LOCUS       DAEOTL010000001       152599 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEOTL010000001 DAEOTL010000000
VERSION     DAEOTL010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 152599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 152599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..152599
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.001"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            160..1440
                     /locus_tag="KRH82_000001"
     CDS             160..1440
                     /locus_tag="KRH82_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBG8653312.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSSISFSLDDTIFKTLISY
                     DIKATNIYNLIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(1703..3094)
                     /locus_tag="KRH82_000002"
     CDS             complement(1703..3094)
                     /locus_tag="KRH82_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBG8653313.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKCP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(3105..4325)
                     /locus_tag="KRH82_000003"
     CDS             complement(3105..4325)
                     /locus_tag="KRH82_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBG8653314.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(4339..5127)
                     /locus_tag="KRH82_000004"
     CDS             complement(4339..5127)
                     /locus_tag="KRH82_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBG8653315.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEEKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(5144..6418)
                     /gene="larA"
                     /locus_tag="KRH82_000005"
     CDS             complement(5144..6418)
                     /gene="larA"
                     /locus_tag="KRH82_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBG8653316.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(6536..7249)
                     /locus_tag="KRH82_000006"
     CDS             complement(6536..7249)
                     /locus_tag="KRH82_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBG8653317.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     DKAKEHMDFISKNYRKNEN"
     gene            7374..8633
                     /locus_tag="KRH82_000007"
     CDS             7374..8633
                     /locus_tag="KRH82_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBG8653318.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTIIQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            8901..9467
                     /locus_tag="KRH82_000008"
     CDS             8901..9467
                     /locus_tag="KRH82_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8653319.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(9668..10873)
                     /locus_tag="KRH82_000009"
     CDS             complement(9668..10873)
                     /locus_tag="KRH82_000009"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBG8653320.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(10976..11082)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(11174..11542)
                     /locus_tag="KRH82_000010"
     CDS             complement(11174..11542)
                     /locus_tag="KRH82_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBG8653321.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(11594..12871)
                     /gene="obgE"
                     /locus_tag="KRH82_000011"
     CDS             complement(11594..12871)
                     /gene="obgE"
                     /locus_tag="KRH82_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBG8653322.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(12982..13272)
                     /gene="rpmA"
                     /locus_tag="KRH82_000012"
     CDS             complement(12982..13272)
                     /gene="rpmA"
                     /locus_tag="KRH82_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBG8653323.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(13286..13603)
                     /locus_tag="KRH82_000013"
     CDS             complement(13286..13603)
                     /locus_tag="KRH82_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBG8653324.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(13618..13929)
                     /gene="rplU"
                     /locus_tag="KRH82_000014"
     CDS             complement(13618..13929)
                     /gene="rplU"
                     /locus_tag="KRH82_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBG8653325.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(14030..15451)
                     /locus_tag="KRH82_000015"
     CDS             complement(14030..15451)
                     /locus_tag="KRH82_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBG8653326.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(15469..16170)
                     /locus_tag="KRH82_000016"
     CDS             complement(15469..16170)
                     /locus_tag="KRH82_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBG8653327.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(16172..18016)
                     /locus_tag="KRH82_000017"
     CDS             complement(16172..18016)
                     /locus_tag="KRH82_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBG8653328.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            18335..19528
                     /locus_tag="KRH82_000018"
     CDS             18335..19528
                     /locus_tag="KRH82_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBG8653329.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(19740..20561)
                     /locus_tag="KRH82_000019"
                     /pseudo
     CDS             complement(19740..20561)
                     /locus_tag="KRH82_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428476.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(20691..21482)
                     /locus_tag="KRH82_000020"
     CDS             complement(20691..21482)
                     /locus_tag="KRH82_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653330.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(21486..21815)
                     /locus_tag="KRH82_000021"
     CDS             complement(21486..21815)
                     /locus_tag="KRH82_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653331.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(22299..22712)
                     /locus_tag="KRH82_000022"
     CDS             complement(22299..22712)
                     /locus_tag="KRH82_000022"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBG8653332.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(22753..23883)
                     /gene="rodA"
                     /locus_tag="KRH82_000023"
     CDS             complement(22753..23883)
                     /gene="rodA"
                     /locus_tag="KRH82_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBG8653333.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(23968..24252)
                     /gene="minE"
                     /locus_tag="KRH82_000024"
     CDS             complement(23968..24252)
                     /gene="minE"
                     /locus_tag="KRH82_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBG8653334.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(24270..25067)
                     /gene="minD"
                     /locus_tag="KRH82_000025"
     CDS             complement(24270..25067)
                     /gene="minD"
                     /locus_tag="KRH82_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBG8653335.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(25091..25774)
                     /locus_tag="KRH82_000026"
     CDS             complement(25091..25774)
                     /locus_tag="KRH82_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBG8653336.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(25872..28850)
                     /locus_tag="KRH82_000027"
     CDS             complement(25872..28850)
                     /locus_tag="KRH82_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBG8653337.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMLTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVVRQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(28862..29350)
                     /gene="mreD"
                     /locus_tag="KRH82_000028"
     CDS             complement(28862..29350)
                     /gene="mreD"
                     /locus_tag="KRH82_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBG8653338.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(29365..30258)
                     /gene="mreC"
                     /locus_tag="KRH82_000029"
     CDS             complement(29365..30258)
                     /gene="mreC"
                     /locus_tag="KRH82_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBG8653339.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(30268..31278)
                     /locus_tag="KRH82_000030"
     CDS             complement(30268..31278)
                     /locus_tag="KRH82_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBG8653340.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(31399..32058)
                     /gene="radC"
                     /locus_tag="KRH82_000031"
     CDS             complement(31399..32058)
                     /gene="radC"
                     /locus_tag="KRH82_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBG8653341.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(32103..32687)
                     /gene="maf"
                     /locus_tag="KRH82_000032"
     CDS             complement(32103..32687)
                     /gene="maf"
                     /locus_tag="KRH82_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBG8653342.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(32863..33834)
                     /locus_tag="KRH82_000033"
     CDS             complement(32863..33834)
                     /locus_tag="KRH82_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBG8653343.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(33850..34425)
                     /gene="rsxA"
                     /locus_tag="KRH82_000034"
     CDS             complement(33850..34425)
                     /gene="rsxA"
                     /locus_tag="KRH82_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBG8653344.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(34440..35033)
                     /locus_tag="KRH82_000035"
     CDS             complement(34440..35033)
                     /locus_tag="KRH82_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBG8653345.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(35046..35615)
                     /locus_tag="KRH82_000036"
     CDS             complement(35046..35615)
                     /locus_tag="KRH82_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBG8653346.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(35615..36592)
                     /locus_tag="KRH82_000037"
     CDS             complement(35615..36592)
                     /locus_tag="KRH82_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBG8653347.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(36615..37952)
                     /gene="rsxC"
                     /locus_tag="KRH82_000038"
     CDS             complement(36615..37952)
                     /gene="rsxC"
                     /locus_tag="KRH82_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBG8653348.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(38168..39112)
                     /locus_tag="KRH82_000039"
     CDS             complement(38168..39112)
                     /locus_tag="KRH82_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653349.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(39223..40497)
                     /locus_tag="KRH82_000040"
     CDS             complement(39223..40497)
                     /locus_tag="KRH82_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBG8653350.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNSTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(40629..41000)
                     /locus_tag="KRH82_000041"
     CDS             complement(40629..41000)
                     /locus_tag="KRH82_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8653351.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(41228..41827)
                     /locus_tag="KRH82_000042"
     CDS             complement(41228..41827)
                     /locus_tag="KRH82_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653352.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(42028..42240)
                     /locus_tag="KRH82_000043"
     CDS             complement(42028..42240)
                     /locus_tag="KRH82_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBG8653353.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(42313..44028)
                     /locus_tag="KRH82_000044"
     CDS             complement(42313..44028)
                     /locus_tag="KRH82_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8653354.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(44028..44582)
                     /locus_tag="KRH82_000045"
     CDS             complement(44028..44582)
                     /locus_tag="KRH82_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBG8653355.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(44575..45177)
                     /locus_tag="KRH82_000046"
     CDS             complement(44575..45177)
                     /locus_tag="KRH82_000046"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBG8653356.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKIFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(45186..47834)
                     /gene="polA"
                     /locus_tag="KRH82_000047"
     CDS             complement(45186..47834)
                     /gene="polA"
                     /locus_tag="KRH82_000047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBG8653357.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFRINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            47986..48073
                     /locus_tag="KRH82_000048"
     tRNA            47986..48073
                     /locus_tag="KRH82_000048"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48020..48022,aa:Leu,seq:caa)
     gene            complement(48260..48703)
                     /locus_tag="KRH82_000049"
     CDS             complement(48260..48703)
                     /locus_tag="KRH82_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653358.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(48706..48903)
                     /locus_tag="KRH82_000050"
     CDS             complement(48706..48903)
                     /locus_tag="KRH82_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653359.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(49095..49961)
                     /locus_tag="KRH82_000051"
     CDS             complement(49095..49961)
                     /locus_tag="KRH82_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8653360.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPN"
     gene            complement(50187..51056)
                     /locus_tag="KRH82_000052"
     CDS             complement(50187..51056)
                     /locus_tag="KRH82_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8653361.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(51562..51783)
                     /locus_tag="KRH82_000053"
     CDS             complement(51562..51783)
                     /locus_tag="KRH82_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653362.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(52284..53264)
                     /locus_tag="KRH82_000054"
     CDS             complement(52284..53264)
                     /locus_tag="KRH82_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653363.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(53428..54300)
                     /locus_tag="KRH82_000055"
     CDS             complement(53428..54300)
                     /locus_tag="KRH82_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8653364.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(54464..55015)
                     /locus_tag="KRH82_000056"
     CDS             complement(54464..55015)
                     /locus_tag="KRH82_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653365.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(55035..55937)
                     /locus_tag="KRH82_000057"
     CDS             complement(55035..55937)
                     /locus_tag="KRH82_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBG8653366.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(55952..58324)
                     /locus_tag="KRH82_000058"
     CDS             complement(55952..58324)
                     /locus_tag="KRH82_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBG8653367.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(58545..59234)
                     /locus_tag="KRH82_000059"
     CDS             complement(58545..59234)
                     /locus_tag="KRH82_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653368.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYIK
                     FIYNLFKSLTNTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(59477..60856)
                     /locus_tag="KRH82_000060"
     CDS             complement(59477..60856)
                     /locus_tag="KRH82_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8653369.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGVLIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEICLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENVNKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(60850..61563)
                     /gene="rgbR"
                     /locus_tag="KRH82_000061"
     CDS             complement(60850..61563)
                     /gene="rgbR"
                     /locus_tag="KRH82_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBG8653370.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(61813..62373)
                     /locus_tag="KRH82_000062"
     CDS             complement(61813..62373)
                     /locus_tag="KRH82_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBG8653371.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(62469..63272)
                     /gene="zupT"
                     /locus_tag="KRH82_000063"
     CDS             complement(62469..63272)
                     /gene="zupT"
                     /locus_tag="KRH82_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBG8653372.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(63423..64586)
                     /locus_tag="KRH82_000064"
     CDS             complement(63423..64586)
                     /locus_tag="KRH82_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8653373.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDVLEIGTALYVQYAVDFLNK"
     gene            complement(64646..65833)
                     /locus_tag="KRH82_000065"
     CDS             complement(64646..65833)
                     /locus_tag="KRH82_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653374.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(66196..67896)
                     /locus_tag="KRH82_000066"
     CDS             complement(66196..67896)
                     /locus_tag="KRH82_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653375.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(68139..68414)
                     /locus_tag="KRH82_000067"
     CDS             complement(68139..68414)
                     /locus_tag="KRH82_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8653376.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(68533..69105)
                     /gene="mobB"
                     /locus_tag="KRH82_000068"
     CDS             complement(68533..69105)
                     /gene="mobB"
                     /locus_tag="KRH82_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBG8653377.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(69089..70270)
                     /locus_tag="KRH82_000069"
     CDS             complement(69089..70270)
                     /locus_tag="KRH82_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBG8653378.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASIG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEHLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(70481..71215)
                     /locus_tag="KRH82_000070"
     CDS             complement(70481..71215)
                     /locus_tag="KRH82_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653379.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            71577..72482
                     /locus_tag="KRH82_000071"
     CDS             71577..72482
                     /locus_tag="KRH82_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8653380.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            complement(72642..73484)
                     /locus_tag="KRH82_000072"
     CDS             complement(72642..73484)
                     /locus_tag="KRH82_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBG8653381.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(73468..74226)
                     /locus_tag="KRH82_000073"
     CDS             complement(73468..74226)
                     /locus_tag="KRH82_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8653382.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            complement(74243..74713)
                     /locus_tag="KRH82_000074"
     CDS             complement(74243..74713)
                     /locus_tag="KRH82_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8653383.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            complement(74713..75456)
                     /locus_tag="KRH82_000075"
     CDS             complement(74713..75456)
                     /locus_tag="KRH82_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBG8653384.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            complement(75460..75873)
                     /locus_tag="KRH82_000076"
     CDS             complement(75460..75873)
                     /locus_tag="KRH82_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8653385.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            complement(75899..76483)
                     /locus_tag="KRH82_000077"
                     /pseudo
     CDS             complement(75899..76483)
                     /locus_tag="KRH82_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(76668..77051)
                     /locus_tag="KRH82_000078"
     CDS             complement(76668..77051)
                     /locus_tag="KRH82_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8653386.1"
                     /translation="MKISKLPEAELKVMRYIWEANDVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNAMVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            complement(77161..77538)
                     /locus_tag="KRH82_000079"
     CDS             complement(77161..77538)
                     /locus_tag="KRH82_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8653387.1"
                     /translation="MKEEILVEKLLRAELIVMEYLWKKDSLVTKKEIVKEMRQVYRWH
                     KSTIKILLKRLVDKGYLARDIIKFQSHYKIIIDNKEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKSISKEKLDALEEYYRNLEE"
     regulatory      77747..77842
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(78059..78235)
                     /locus_tag="KRH82_000080"
     CDS             complement(78059..78235)
                     /locus_tag="KRH82_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653388.1"
                     /translation="MKTLMFILVIAYYITIVIKSITTIVKSITRLLDSISRLKESLHK
                     LRNRPDGNQDDFNE"
     gene            78489..78677
                     /locus_tag="KRH82_000081"
     CDS             78489..78677
                     /locus_tag="KRH82_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653389.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHDYSKK"
     gene            79379..79900
                     /locus_tag="KRH82_000082"
     CDS             79379..79900
                     /locus_tag="KRH82_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBG8653390.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            79876..81462
                     /locus_tag="KRH82_000083"
     CDS             79876..81462
                     /locus_tag="KRH82_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653391.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(81526..82044)
                     /locus_tag="KRH82_000084"
     CDS             complement(81526..82044)
                     /locus_tag="KRH82_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653392.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(82210..82572)
                     /locus_tag="KRH82_000085"
     CDS             complement(82210..82572)
                     /locus_tag="KRH82_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653393.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            complement(82653..83450)
                     /locus_tag="KRH82_000086"
     CDS             complement(82653..83450)
                     /locus_tag="KRH82_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8653394.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSNNYLAEQCEIANRQNVDVAVQIHFNADHTTLNSMGTETIYKTNNGKIY
                     ADRVNTKLATVFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKNINNEGVKQMYKHTIVYDGEVDKILANVLSWGYSPSKVLVCDIKDYV
                     PGQTENLYVVGGGACEKISSITKEKFTMIKGNDRFDTLYKALDFINR"
     gene            complement(83450..83707)
                     /locus_tag="KRH82_000087"
     CDS             complement(83450..83707)
                     /locus_tag="KRH82_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBG8653395.1"
                     /translation="MDSLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            complement(83727..83957)
                     /locus_tag="KRH82_000088"
     CDS             complement(83727..83957)
                     /locus_tag="KRH82_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBG8653396.1"
                     /translation="MNEEVIKEKIKRNEIRINRHSDEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAVQRGIF"
     gene            complement(83992..84174)
                     /locus_tag="KRH82_000089"
     CDS             complement(83992..84174)
                     /locus_tag="KRH82_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653397.1"
                     /translation="MNINNVVVRILAERILNGGLNPLKNRPFELDDVTNTEYRKAVED
                     YIIEHSGVVEGAEPAK"
     gene            complement(84174..84470)
                     /locus_tag="KRH82_000090"
     CDS             complement(84174..84470)
                     /locus_tag="KRH82_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653398.1"
                     /translation="MNVPNRVIYDQTGKIIFETGESCGDVLPHNKITELHYIDIPYGS
                     IDYIKNRIVGINIETKQPILEEIPVYVSEAEKEKQELENQLLLLTNQEIGGGIL"
     gene            complement(84485..86203)
                     /locus_tag="KRH82_000091"
     CDS             complement(84485..86203)
                     /locus_tag="KRH82_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653399.1"
                     /translation="MAIVYEFNYTGAEQSVVLPPGKYKFECFGACGGNYYDFVQCAKG
                     GYTAGSLILKENTTLHVYVGQSGYCKGVNGIETCRSGFNGAGGINTYKSTSDGYYSLA
                     GGGATDIRLIDGNWDNLQSLLSRIIVAGGGGGGSGNSHDSIGHGGGTKGKDGISIANK
                     YFAGGGSQFQGGLTFNSLYNGSFGVSGAGDGISGVGGGGGWYCGAGSFYAEFGGGGSG
                     YILTKNSYKPVNYSPSSKYYFSDINSVVGGNTTKQDGYAKITLLQALPFLTVSSYNST
                     TATFKADHTNPTLLTKIEYFIDDVLKETITTDLTTEKIINYTLEDNALHTLKIVVTDS
                     ANATAEKVVSISKGIAPLPAGSTTDEVTNKWIEIKDTFKSGKTSIINTLALKNIEASL
                     NNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTITQLNTKYKVASGTVTPFKGDDT
                     KIAYPYLTDRVFKPSAWVKISNLDFKPNIFFADFDYYDTEYKNNYKLFLFACCGVATQ
                     RGVDFSSVTSFVRKSSDEYFHANGWLYNNSEGDVYFNNTGVQIPAYSFDSTQRHIYKW
                     YAIKFI"
     gene            complement(86220..87020)
                     /locus_tag="KRH82_000092"
     CDS             complement(86220..87020)
                     /locus_tag="KRH82_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBG8653400.1"
                     /translation="MADEQFYTILTNIGKAKIANAGMLGKPVVLEKIQAGDGGGNYYN
                     PTEDQAALKNKVWEGNINAFDNDENNPNWIIATACIPGSIGGFTVREMGLIDNEGDMI
                     AICKSPETYKPKVGNGAMKDLYLKFIIEVSNVEKVTLVVDPTAIFLTKKDEEKIKTSI
                     TNLDKKITDNNTATNKKIDDAKKELGDKIGDTTQLTTIDKTNIVSALNEVKASVDSIE
                     TTAEKTSYNNATSNLIATNVQGAIDEVVRKIENFNEVNISIQNDMLPI"
     gene            complement(87033..87662)
                     /locus_tag="KRH82_000093"
     CDS             complement(87033..87662)
                     /locus_tag="KRH82_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBG8653401.1"
                     /translation="MITSKKGKEMLLTLSPIYEQSLVMNSIYEAIGSEFDNLELLNKE
                     IELQLFPQTATWGLGFWENRVGLITNLDEDMETRRRKVIAKLQSKYIMTPKRMSMILQ
                     SYTGADIKINENIAPYTFGVELTSTQGFPRSLEDLYKRVNVIKPSHLSVSYKLVSLLK
                     SRTYFAQTTIMSEEITVYPYTSKEVKASVKAKFALAHNMSSETLTVYPR"
     gene            complement(87659..88792)
                     /locus_tag="KRH82_000094"
     CDS             complement(87659..88792)
                     /locus_tag="KRH82_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBG8653402.1"
                     /translation="MERELPIPVFLTEDEDSVHERMLSNFQDVSTLEGDFIYDATRPT
                     AEQIAELKQLGLQNNLKIAFPQTSYGTYLEWLGECKGVFKNQPTKATGVITFTGVQGT
                     IITKGTIVTTIATDEKQSIEFELLETKTIGENETVDIKAESRIVGTIGNVSKGSISVL
                     LGSINGVKSVTNKDFKGGTDIEDEEHFRERVLVAEQEDKLSGASSDYIRWAKEVDGVG
                     YAYVVPEWNGAGTVKVLILDKNRKAATQELIDKVQEYIYPLNISEGENRDGKAPIGAL
                     VTVVTPDTLLINVKASFIFSNSFNEETVLNNLKTKIDKYLDKIDLGGTVSYNAIQAIV
                     GSMMLTDEGIQDFSNLTINDAKENIKLQDQVVGIGEIVNEVVG"
     gene            complement(88801..89259)
                     /locus_tag="KRH82_000095"
     CDS             complement(88801..89259)
                     /locus_tag="KRH82_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBG8653403.1"
                     /translation="MPNLFPQSETFETVELKNNDENELDLKGSFLFDFEKGEFVKNAD
                     GTLKKCDKVQAYKQWCQKAILTPRYKKAAYTNIYGSEIKDLIASNLSQSAKELEITRL
                     IKETILVHPYTKEVGEFSFNWLENSRLVEYEFDVLTIDDENIVIDGNIKR"
     gene            complement(89234..89599)
                     /locus_tag="KRH82_000096"
     CDS             complement(89234..89599)
                     /locus_tag="KRH82_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653404.1"
                     /translation="MTDARFNGIARILKENMNKSVANGTFGMGCELAEITANGLKVNG
                     YKDEIQDYLVLENLTLKEDYFTFSDEALSGEYRHKHKIETPKELKPLRIGDNVLVAVM
                     GAEFVVIGRVVNAKPISSK"
     gene            complement(89592..90554)
                     /locus_tag="KRH82_000097"
     CDS             complement(89592..90554)
                     /locus_tag="KRH82_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdQ"
                     /protein_id="HBG8653405.1"
                     /translation="MKIILNGKYDIANFNEGITLSEAIDGVAYKMDVSLVEPKQLKDI
                     NIKKGDKIILIDIAYESKKEETIFDGVVWETRRSEKSKKLTLSCRERTVYMEESEEQY
                     QFKENTATQRIEYYCKQWNIPYYNLANTGKKLAKVIHKTNILDMIKKDLKETATKGGD
                     LFRVRMDNKLKLFKLGTNANVYKLDSILEDANFTSSFNDAVTSVKVLGKSKDENTKAP
                     IIGTYKKDADKFGTLQKIKQDEKIKNAKEAKKAAEAMFNSGEETISVDCAVDINRIRA
                     GDKVSLKSKEYYVIDVTHTLDSRPKMKLNIGSLEYIRRKFYNND"
     gene            complement(90551..91222)
                     /locus_tag="KRH82_000098"
     CDS             complement(90551..91222)
                     /locus_tag="KRH82_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBG8653406.1"
                     /translation="MVIDIYLKNEKEKIDFHFPVNPQDSLSIKKEKRFETVDIVNLGE
                     FDIKKEGEKIREISFKTFLPNLYDASYCRYSELKNPIEVVAMLEKWVDQAEPLRLIIT
                     GFGYNGLVTISSFSNTQTAGREEDRDIEITFRTYRELKIETLKKDTKSNTKTDLKDNR
                     PNTQTKSKIYTVKASDTLYKIAKNLLGKGSRWPEIYNIPENKKVIGKNPNIIKKGQKL
                     VIPSK"
     gene            complement(91291..92034)
                     /locus_tag="KRH82_000099"
     CDS             complement(91291..92034)
                     /locus_tag="KRH82_000099"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653407.1"
                     /translation="MWQKFKSMNGILKIIIGIIAIILLPITLVLLSIEFLVKAIGSKK
                     KAKIALGCILVFLTTLCTRNVYNVLSIEKEEHIPVKQVSYNDKDKGKSENNIQEQQQK
                     KEESKKLEEQKKNEEKEQNNEPTKFFTDVYLKNKNCVNMTSYEGIKSNLDIFGYKYEV
                     IEPNETTLRQINVYDNQSNDTIQFQFYENDTGEEVVTVMQYNKKDEPDKSVAISDGFH
                     TQPPKFQNHINNTNKEVNSIEEQINFMFN"
     gene            complement(92116..96390)
                     /locus_tag="KRH82_000100"
     CDS             complement(92116..96390)
                     /locus_tag="KRH82_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBG8653408.1"
                     /translation="MREIAKKEMYHIDVVISAKGDGETKSKLSAMEKYMKQTEKRMQT
                     LNRIKVNPAIKATDKASSVVNRVNNNMNKAKKTVTARIKATDNASPVANRASNNVNKA
                     KKTVTARLKATDNASSTVNKVNNKIKEVAKPVPPVIIRGQDESSSIIDKVKAKIQNLK
                     ADTIIKIKSQADEAINTISRTKNKLQEFVSKRYEAAVKIRDEASSALRGLTGKIDSFV
                     SGAISKFARLATTAGALIGGIGVGSAVKGFATFEQSMKNTQAVSGATGKEMEALTAKA
                     RQLGRETSFTAKDAGDAMYYMGMAGWKSEQMIKAIPDVLNLAAAGGTDLALTSDIVTD
                     GLTALGMTANDTTEFVDVMAATITNSNTSVELMGETFKYVGSMGGALGVSMKDLSLAT
                     GLMASASVKGSMAGTSLRGGLVRLIKPPEEAASAIKKYGIELKKNKNGSLDLAGTIGS
                     LREKLGGLKDVEKGVAISSIFGRTAMAGWAAVVNASESDFNKLTTAIAESEGEAKRIA
                     NMKLDTLSGQFEILKSAIDDVRISVGQRLGPMTRGFVEDLIKKMPQIGDAIVGVVEKF
                     VNNFDKIKAGFQVLLPAIGSVIASVMVLKATFAFGGAIKSLSLLASTFGTAKLVAFGL
                     TVGIGAIVIAFAGMTVAISNNKTAMMDLQTRFGSFGEYVTTIMETVGGVIKLTLGNLL
                     IMLGGIGKGIGILLSDKSWDEKASSLKNLFGKTTAEIKTNTKEALSDINGETSNATAL
                     LKKSTSKELQGVTKAFSTAFDQSKNVTEKKSSDIARALTNGLKGLDDQSLTMMRGLND
                     NMAIILSGVTADMKPSDKVNKITKNLDDAFKAGKLSAQEYRSSIQETLNFISKYSADS
                     SNNLKQGMSDAFNAFKEGTNIGGLKDGVTGMLNSLKATGPQALETLKGLGGKASEIFK
                     GVDFNSSIDAQKTKVLQNLNSLGLEGTQAIDTLRTIFSQASSALDTTNLKQGLSNTFN
                     SFKEGFNSGGIKNAINSMLGTINQAGPQMQQALGKMDGKMGQVFANVDFSTPIETQAS
                     KVLENLNNLGIEGPKALETVRSIFAQASSQIQGSASQTAQQANQEVANALTQGNPAVQ
                     QAGQQLGTDLTNGVVNGVQAGVPVVQQKSNELATATQNGVTNAVNSATPQIDNSNLTS
                     GIDTAFNQATATVQQGASSMYNGAKQSFTQLAQIGREAGSSLYNGATTSFNMLATNVR
                     VACSSMYNGARTSFTSLSSSAISAISAMCSSVVSQVSAMSSQIISYWNSVRATVSAPI
                     TASFNVKTTQTTVKRTVNESSGGILGNILDRFADGGVATRTSICGENGAEMVIPLTNT
                     RRSRAIELYEQTGKMLGLGSTPSQKVGNSNIVNNVRQFPLANVLDTDNKEYKEATPNS
                     VNSSNNTINLGGISINVQNSDNKEEMIQELLSQVESGIREALQDIG"
     gene            complement(96409..96561)
                     /locus_tag="KRH82_000101"
     CDS             complement(96409..96561)
                     /locus_tag="KRH82_000101"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653409.1"
                     /translation="MGGRLTVLNNIFVKHHVPPDVYVKKNLMSQRLMKVFTQNEIEQE
                     NKAMKK"
     gene            complement(96567..97058)
                     /locus_tag="KRH82_000102"
     CDS             complement(96567..97058)
                     /locus_tag="KRH82_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653410.1"
                     /translation="MSEIYKRELENEVVEDNDLDEEIEETNEDRLKMKEDEIIAKLLE
                     DSPVPQRTVFLDRLGIPITLKALTEKEISKIRKECTKIVKVQGRREEKLNDDEFTLAL
                     IEKGTVKPNFSNQKLLNAMKVTNAREFIKRKFLAGELSKISDQILELSGFYDEISDDD
                     IKN"
     gene            complement(97142..97555)
                     /locus_tag="KRH82_000103"
     CDS             complement(97142..97555)
                     /locus_tag="KRH82_000103"
                     /inference="COORDINATES: protein motif:HMM:NF020949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653411.1"
                     /translation="MYNDDYIEEASFLNGSDVVILIDGVEELYMEEIKADFEQDEQSI
                     KLLGCQNEISRVGTTKGSFSLNGYKTDSKFAKLGFRSFEIIYNLSNSETLGYESIRLK
                     NCRLKKLPLINSKAGEIVKIEVEGSFRGYDLLNEL"
     gene            complement(97571..98992)
                     /locus_tag="KRH82_000104"
     CDS             complement(97571..98992)
                     /locus_tag="KRH82_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBG8653412.1"
                     /translation="MATGTWNEKEKKEIPGFYNRFKTQAEKSANTGLKGRLAIPVKAN
                     WGEVGKVVTIKNDLRQLKTLFGDDMNYSAYKLGKLALLGNVKELLLYRLVDGKQKKGT
                     LTLKDTTENSAKDVIKLETKYPTARNFNVTIKSNLVDSDKKDFIFFENTKQLFSSSIK
                     GTIDEIVLEINSNLDNEYVIATKVADSDTILANVVNQALEGGNDGCTSITNESYLKAL
                     EEFERYSFDSFVLDGVADEALQETTKAWVAKNKELGKDILLFLGGKTEDNIKQINDKS
                     KSFNDENIVNVGSSAYYENIKYTPSEVAVYIAALSVSKGITGSICNAKTIFEEVEPRL
                     SQSEVKECLKSGTLVLDFDDGDVIIVDDVNTFKKYVDDKNEAMGYISNIMFINTINKD
                     TSLKRKEFVGKIFNDATGQTTVICALKKYFEELMSQGIISEFNVDIDTELQATAKADE
                     FYWKWDAVKVDVMKKIYGTGYLG"
     gene            complement(98994..99197)
                     /locus_tag="KRH82_000105"
     CDS             complement(98994..99197)
                     /locus_tag="KRH82_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653413.1"
                     /translation="MAETINKKTNVSKQEEKYLKNDFLKNSEALGYEKMVVAGALFNC
                     KKEELTKSEFEKLIKDFLEREVK"
     gene            complement(99210..100031)
                     /locus_tag="KRH82_000106"
     CDS             complement(99210..100031)
                     /locus_tag="KRH82_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653414.1"
                     /translation="MRAGIRKALIDNIKELKGCYEPNVPNKDTKKPYMVVVQGQDNDN
                     GETIGFERSIEVWIYEGRTTFKKLDKLTKQVIEILDMNTIVDESENEAFTCIYKGTSE
                     NDIVVEEWDAIARGIRFSVIALEDKEDATSDRWVEALSKYTKDLLEIESYKDNWKKNF
                     IAPCALWRTTNVENKRINYHLIEITKTMKCHVVSKNKDEIVKFLEALETSLIIDKRVR
                     LREDKNMYLTLVSVVEDRESDMFTTGQLTVVFKMIGKIKREGPIMDKIYSNGNLK"
     gene            complement(100032..100442)
                     /locus_tag="KRH82_000107"
     CDS             complement(100032..100442)
                     /locus_tag="KRH82_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653415.1"
                     /translation="MSAFTNAINDINRKKAGMFVLCMSASAMLEGEAKANASWTDRTS
                     HARQSLNAKTLGGGNNFIIRLSHGAEYGGILEEGSKPHVITPKSAQALYWRGASHPVK
                     SVQHPGTKAMPIIKPTIDKNIGKIGNMIFRYWSD"
     gene            complement(100444..100821)
                     /locus_tag="KRH82_000108"
     CDS             complement(100444..100821)
                     /locus_tag="KRH82_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653416.1"
                     /translation="MINIDRRRKDIIRTINMNPTNITITNIKKTEIDGAFEETETEIK
                     CVVRIFNEKTAEKQISSEKQGTFSSIRTYGMLVSDDVVLDVNSRDSLEFECIYGRMKI
                     VNVYPQIVKGELCGYQCSLERID"
     gene            complement(100818..101156)
                     /locus_tag="KRH82_000109"
     CDS             complement(100818..101156)
                     /locus_tag="KRH82_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653417.1"
                     /translation="MTPTSNLIEKLRLLLNDKDKKSFTDEELNLFLEEADCIYCAASQ
                     GWVLKSLQYENTVGEMYEYKVGQETYKSSSIKDLVSVAYQNAEKFKDMCTNKKEKGSF
                     MLGISTEFEI"
     gene            complement(101196..102233)
                     /locus_tag="KRH82_000110"
     CDS             complement(101196..102233)
                     /locus_tag="KRH82_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HBG8653418.1"
                     /translation="MAFKVISQENLLEQKRKETLQEDIPFIVNGEMEYVTKKISNGEM
                     ETLELNKPLGEMMTFSSTSNLKELLRKVVLDVELGREQVQLLYKPIYDSIADSNLPQV
                     MDAKWALQGNCVFLEHIEGEEIKFGTINAENGPVARIQTYATGFEYTKEMKDFNQTFS
                     VEILNKSIGESYNALLNHIHLSPIINFNYKASNKTAFKGETNDPIWLGIWRTLTQAQK
                     DTVIAKRQGNILMASSADQIEIEMALNGGHLLNGSMYPSIKNISTVIYYDGWEVTVGK
                     KTYSYKGVTPGKGYLIRPKRGFKELIKRDLTTEVGNADLSKLVENQIVGHCYRGAFAA
                     VEENVQEISFR"
     gene            complement(102252..102635)
                     /locus_tag="KRH82_000111"
     CDS             complement(102252..102635)
                     /locus_tag="KRH82_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HBG8653419.1"
                     /translation="MAFKGQPTPSTITQITRAKISDGKSVRVILSEGESTKTQQFYLI
                     NGFFGVAMQDGEKGDEVTLQIEQAEYETDNIVTSEAFEAGKLIYWDNTAKKFTTTSAS
                     NRLVGRVTDGKDSNNVIWFILLPQQ"
     gene            complement(102651..103985)
                     /locus_tag="KRH82_000112"
     CDS             complement(102651..103985)
                     /locus_tag="KRH82_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653420.1"
                     /translation="MNVITGEMDSMNALISSIKPSDIPLAKDIDIEALKSIDDDPLEV
                     VVEIPATKSKRGWNYTAKSLKDIVDYTNENTLNGFLGHQKAENISTEFALPVTHWIGA
                     EMKGDKAYFRGLIDADATNLKRWIRTKRIKEVSIFGYPKLKKSAKGEMNVIGYEPLSI
                     DWTPLHRPGMPTSIVGMEMSPNGEQLDGTFEALRIDLREALKAKFSINDNNSYLYIQN
                     IRYDNNTVIYELEQNGLCKLYSIPFTIVENKINLGEEIEVIKKISYEAKGEMKGEENK
                     LEGKELIKNVKGLLQTGEISYSEVIQGIGLTKEIVTGEMEDVKSSLKAEKELREVKKV
                     LGIVGEMDTVEVAKKASKALENEKKEAWNCIVNKVIKDKVSGEIAQTLVKKMLNVEEG
                     SSEEVITGEIENILNDEFVKNTMSNMYKDNPTTTGLLNSSNNGSLTTKKNRI"
     gene            complement(104005..105018)
                     /locus_tag="KRH82_000113"
     CDS             complement(104005..105018)
                     /locus_tag="KRH82_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653421.1"
                     /translation="MAMDKSTSELITVAGEYKKWALEARKKFIDLRLKQDDEIRTMYI
                     NITRNITKEIRKGNLSDFNKVRLKQILKQLTQEIKILNEQLVFNFDEYLNKNVETATS
                     YSKNILINAVETAQITKVTKTMIQKAFYDINIRTVEAYYTRVKDGLFLSDRIWSKCKK
                     YREDMKVILQTAVTEGQDCVKTAKMLDKYVLKGKKTLVDEYPNMIKRIGNRVPQNISY
                     EALRLARTEMTSAYGDGVLASAMINPATIGIQFMLSMAHPHTDICDEICGEDNFGLGK
                     GVYPINEAPVYPFHPHCLCIMLTVVQPLDILVGRLKNWIKNPMNDVPLEMWYQEVYGN
                     LNF"
     gene            complement(105005..106507)
                     /locus_tag="KRH82_000114"
     CDS             complement(105005..106507)
                     /locus_tag="KRH82_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBG8653422.1"
                     /translation="MGIISYVKKLFKRPAGEIMRMSSGNIGVYKLDDSRVDYELAREL
                     YQNKNAKYKLGSSFVRPIVNSTTGFMGVPHFQIEDEEAQYILDEFVLDNTSKMLKTHT
                     DSLKQGDCYIWITREERENPLYPDKKVRLIYNFISPEEVKEIILDPTTKEPIAYILES
                     QNEWTDLGENKRKAKVKQIITAESRFVEVEGDKIEGLEEGETPNVWGFIPIIHFKNEA
                     DETLKYGQSDIEPIEPLLKAYHDVMLHALKGSKMHSTPKLKLKLTDVASFLAHNFGVE
                     DPVKFAKEGGKINLDGHEILFLNKDEEAEFVEVKSAIGDAKELLKLLFYCIVDVSETP
                     EFIFGVHTPSALASVKEQMPIMVNKIRRKREQFTNSWQLLARMVLIMSSNSSGMKYSS
                     YDVTIGWDEVNPRDDKELAETLEKVCSALDKALEGGFISEESTVNFLAQYIDTMSNYI
                     SDDPEIVGEREKIIKTKMLKYRLDDSQGLNDESNEIEKEINKIKDNNGNG"
     gene            complement(106498..107907)
                     /locus_tag="KRH82_000115"
     CDS             complement(106498..107907)
                     /locus_tag="KRH82_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase B"
                     /protein_id="HBG8653423.1"
                     /translation="MDKALLTLLDCYWDNPVWFAEDMLNFKADKWQSDVLMALAQTPK
                     VSIRSGQGVGKTGLESIATVWYLSTRPFPKVVATAPTRQQLYDVLWAEIAKWLSNSKV
                     EKLLEWTKTKVYMKGFEERWWATARTAVKPENMQGFHEDYMLFVVDEASGVADPIMEA
                     ILGTLSGAENKLLLCGNPTRTSGTFYDSHNRDRDLYKTFKVSSLDSPRTSKDNIEMLK
                     RKYHEGSDPWRVRVLGEFPKGESDSLISLEAVETSTIREVNISNDYILNIGADIARYG
                     DDETIIAPRIGGKVFDLLTYSKKDTMETVGNILRAVDKFKNMYHQINRVKIKTDDDGL
                     GAGVTDRLKEVIRHERLKYEVIPIQNGSSAIEKDKYYNKASEMWDNMREELDANLSSF
                     IQNKEAIIQLPNDDKLIKQLSNRKYTVDSKGKIQIESKKEMKKRIGESPDRADAVIYS
                     FAENNNTDLSLLKGGSVWG"
     gene            complement(107900..108601)
                     /locus_tag="KRH82_000116"
     CDS             complement(107900..108601)
                     /locus_tag="KRH82_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653424.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISAKYDISLNTLKSWIKRYNWANE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQKNRVEKLKCEVDNLKKSDTGDDSKIWV
                     EAIQNIAMKRGVNNG"
     gene            complement(108772..109029)
                     /locus_tag="KRH82_000117"
     CDS             complement(108772..109029)
                     /locus_tag="KRH82_000117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653425.1"
                     /translation="MNDYKEKTEPKLNILVQSKVDILCSNSSTMNGVDTSIDIKLSLD
                     NRVIGNLTNEDIKKEISTSFNKCLKEIDKKICSKEVINKLI"
     gene            complement(109076..109273)
                     /locus_tag="KRH82_000118"
     CDS             complement(109076..109273)
                     /locus_tag="KRH82_000118"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653426.1"
                     /translation="MSNLREKIIKELNEFNIKADNDFLEYAVEHIKKFMNEGIADEEL
                     LIRGVVLGASYVVNIENKDLD"
     gene            complement(109724..110212)
                     /locus_tag="KRH82_000119"
     CDS             complement(109724..110212)
                     /locus_tag="KRH82_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653427.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSTVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            complement(110315..111163)
                     /locus_tag="KRH82_000120"
     CDS             complement(110315..111163)
                     /locus_tag="KRH82_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBG8653428.1"
                     /translation="MNENINKEITVLGTLEIEGMKFHNIEGGFGEHKKAMLVKDIAEI
                     HNRESRQINELINKNRKRFKDGKDILDLLGVGLDDTKIKELGFTQQSINSYRGLKNKG
                     LLSGIYILSERGYAKLLKILEDDIAWELYEKLVDGYFSMRKELNNPLLSASKELQAIF
                     MLDKKQEVLETKIENVNEKLENFMDDAPLFNIECESIVKEVKKVATKSLGGHGSKAYK
                     NKSLRGKVYNDIYHQIKREFGVDSYKAIKRCQLNKVLEIVNNYKLPIVFEEEIRLLNS
                     QLSIVS"
     gene            complement(111265..111672)
                     /locus_tag="KRH82_000121"
     CDS             complement(111265..111672)
                     /locus_tag="KRH82_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBG8653429.1"
                     /translation="MKVFLVIDGEPIGKERPRFILATKRTYTPNKTRDYEELIRWLYQ
                     SKVKHYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDNPRVEVILEDVI"
     gene            complement(111810..111995)
                     /locus_tag="KRH82_000122"
     CDS             complement(111810..111995)
                     /locus_tag="KRH82_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653430.1"
                     /translation="MVITEFKVTWQTTREWEKGNVYSSIFTDLEEARAFKKDEENIKE
                     NYNVKLLSRAIVEIEID"
     gene            complement(112026..112232)
                     /locus_tag="KRH82_000123"
     CDS             complement(112026..112232)
                     /locus_tag="KRH82_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653431.1"
                     /translation="MKNTGNKVEINNIRELNDALNKYDIPFGILSDVDRRICDWMATG
                     GNEDDAYIKQQYRYVENFINRFCD"
     gene            complement(112213..112500)
                     /locus_tag="KRH82_000124"
     CDS             complement(112213..112500)
                     /locus_tag="KRH82_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653432.1"
                     /translation="MITTQMYKINNEIYLNNICLEENKEITIWVEKNNTHELIWLKIA
                     NVNGKLAIFVQDIENAVIKEWQGRKEYERVLGQIEDKQVEKGEILYEEYWK"
     gene            complement(112593..112901)
                     /locus_tag="KRH82_000125"
     CDS             complement(112593..112901)
                     /locus_tag="KRH82_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653433.1"
                     /translation="MKINLNDIPEGYKVAVIPILEAIKRAKEDEKELREYLKEIEECK
                     KINISIVRKNGTKIPLTFTNKELNIRLKEEIKLAIKCIKEEATEIKELLIKMESEGNK
                     "
     gene            complement(112904..113065)
                     /locus_tag="KRH82_000126"
     CDS             complement(112904..113065)
                     /locus_tag="KRH82_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653434.1"
                     /translation="MTNKEMCKSNNLDEREVYKKFGKEICGSCINDKVDCESKDCDTT
                     YKNWLEKEI"
     gene            complement(113062..113787)
                     /locus_tag="KRH82_000127"
     CDS             complement(113062..113787)
                     /locus_tag="KRH82_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
                     /protein_id="HBG8653435.1"
                     /translation="MKYVASFSGGKDSAAMLLLILEKKLPLDEIVFIDTGLEFEEIYD
                     IIDGFEKRINFKITRIKAEKTFEEYFYTVNKQGKHKGQIWGFPYTLGAWCNSRLKLAP
                     ANKYFNSIGEHKRYIGIAFDEPNRYKRLEKNCIAPLYEAKMTEKDCLKYLEEKGFYYE
                     IHHRFKRTGCYLCPKQSLDSLRTLRKYYPDLWGSMLKLDKDSPVPFRANGVTVHDLEK
                     RFSNEDIENERQISFFQTEKVSI"
     gene            complement(113796..114791)
                     /locus_tag="KRH82_000128"
     CDS             complement(113796..114791)
                     /locus_tag="KRH82_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBG8653436.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDMDLFFQKKISKVSR
                     DNDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFEDDKFNIQMSKNEINIQETKIVKIAVIVG
                     LSGMNDEYHLKVLDKDAEKEEANSKFVTEFLNATKIKDDKYKTKMFKAFVDSYIAHLY
                     SDMKQGEDVRGMLLYMLREKQKLDINEFADKAIKDDLKDSFKDHIEEKGIESFNIDKK
                     WVEKNLKNRHIKTDTGFEIKGKMDDFEDFMKYGIRHNGNGTVDIVIKNVNFYNEK"
     gene            complement(114803..115012)
                     /locus_tag="KRH82_000129"
     CDS             complement(114803..115012)
                     /locus_tag="KRH82_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653437.1"
                     /translation="MSKYVLRWQIGLSLENRKIHYTYGSKEALRKKAKALAKDENIVL
                     ITIDKVDEVIKNTISEKIIERFKNL"
     gene            complement(115030..115719)
                     /locus_tag="KRH82_000130"
     CDS             complement(115030..115719)
                     /locus_tag="KRH82_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653438.1"
                     /translation="MDLNKIMNDALVELEENGFVEEVVKKQLAETIKRVVNEVFGNWG
                     DFSKKIEKHLSENININLDKLDIQKYNVLVATTVKEKIDMTMKVEAIEHLKRNLDNML
                     VGAEKEYKMSELLEILKMDKYDIDEYEGYEDCITFILDENKYGSGWIEIDKEPNKSKY
                     RCEHSILLRKDGTIASYRYENREISSKDIMSGFDNFGDLLFKIFAHGSKIILDLGNDI
                     EDYDLTNGEDY"
     gene            complement(115833..116009)
                     /locus_tag="KRH82_000131"
     CDS             complement(115833..116009)
                     /locus_tag="KRH82_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653439.1"
                     /translation="MDDRLEIINASVNYIQMICESSNIAIIAERGRVRILDLETKEKY
                     DLLKNKLEEMLEEI"
     gene            complement(116125..116265)
                     /locus_tag="KRH82_000132"
     CDS             complement(116125..116265)
                     /locus_tag="KRH82_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653440.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDIAIKILSRYECEGML
                     EK"
     gene            complement(116234..116614)
                     /locus_tag="KRH82_000133"
     CDS             complement(116234..116614)
                     /locus_tag="KRH82_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653441.1"
                     /translation="MAKIWLDAGTFLEKTIDIEDMFELNLRKVRKANESKKIKLKLNE
                     SKFKKIRKKPTNDTKSKPIKVFNIETGEVRIFKSAKAASKYLKISGDYASCLARENRV
                     TREGWKAEYIQEVSDGISKCGASN"
     gene            complement(116632..116853)
                     /locus_tag="KRH82_000134"
     CDS             complement(116632..116853)
                     /locus_tag="KRH82_000134"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653442.1"
                     /translation="MRFEIGKTYKFDKEKFMEINGVEQHKKYKELWIDDIEGVEFTVE
                     KTFDDGYVCYPNEFWFNFGVVSEWCVEVK"
     gene            complement(116858..117019)
                     /locus_tag="KRH82_000135"
     CDS             complement(116858..117019)
                     /locus_tag="KRH82_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653443.1"
                     /translation="MSRTAICSVCGEFLVESYDDQFTNTKVMDLHGREFVIVICKSCL
                     EELLRKCED"
     gene            complement(117089..117496)
                     /locus_tag="KRH82_000136"
     CDS             complement(117089..117496)
                     /locus_tag="KRH82_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBG8653444.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            complement(117512..117685)
                     /locus_tag="KRH82_000137"
     CDS             complement(117512..117685)
                     /locus_tag="KRH82_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBG8653445.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKVAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            complement(117746..118627)
                     /locus_tag="KRH82_000138"
     CDS             complement(117746..118627)
                     /locus_tag="KRH82_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBG8653446.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDAKLSWQAKGLHSYLISKPDH
                     WKIYVNDLYKRSKNGRDSTANILKELIENGYITRKPCRDSNTNKMLGGYDYEVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQSNKDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEAIANGVKNYKYVKTILNN
                     WIEAGVKTNLELTEYQNEFERKKKNKQDKKQSNSKAVNTPNVSKNKFHNFNETFTQYS
                     PDELDDIIKKSQKVKFK"
     gene            complement(118637..119245)
                     /locus_tag="KRH82_000139"
     CDS             complement(118637..119245)
                     /locus_tag="KRH82_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBG8653447.1"
                     /translation="METNNVYIKLVNIQNTLKAPKNQYNNFRKYNYRSCEDILEGLKP
                     ILKEEKALVILDDNIVQIGNRFYVEATATLIDAETGEKISTKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNILYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            complement(119255..119764)
                     /locus_tag="KRH82_000140"
     CDS             complement(119255..119764)
                     /locus_tag="KRH82_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBG8653448.1"
                     /translation="MSTLYELTTDLLEIEEGLTETTGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKKVKKNTLDRLKSNIKDCMELLGTKKVETIL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNIIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            complement(119842..120159)
                     /locus_tag="KRH82_000141"
     CDS             complement(119842..120159)
                     /locus_tag="KRH82_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653449.1"
                     /translation="MKSLTIVRNAVEQQLNRANLEINKNEELYTKLRKKEKRDVLDEI
                     ELSNALREKSVNERLKIFAESLLKIIDTQIEIKEYEESEDYKIFELISEEIERDRPID
                     IQI"
     gene            complement(120162..120308)
                     /locus_tag="KRH82_000142"
     CDS             complement(120162..120308)
                     /locus_tag="KRH82_000142"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653450.1"
                     /translation="MNVRVLIAYVQFCNDKQIKASFEGLRKYNRDIELVNLYLPSKLK
                     IKGD"
     gene            complement(120309..120752)
                     /locus_tag="KRH82_000143"
     CDS             complement(120309..120752)
                     /locus_tag="KRH82_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653451.1"
                     /translation="MSKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKEIREGVI"
     gene            complement(120782..120979)
                     /locus_tag="KRH82_000144"
     CDS             complement(120782..120979)
                     /locus_tag="KRH82_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653452.1"
                     /translation="MAINDNINKILKDRDLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKIADYLDITLDELVGR"
     gene            121032..121232
                     /locus_tag="KRH82_000145"
     CDS             121032..121232
                     /locus_tag="KRH82_000145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653453.1"
                     /translation="MKVGDIMQFSKDILHTLTLEILKEKYDFKSSSEEELLKHYHEIF
                     LKLSEVNNSFSKGDGLSVFKQM"
     gene            complement(121219..121416)
                     /locus_tag="KRH82_000146"
     CDS             complement(121219..121416)
                     /locus_tag="KRH82_000146"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653454.1"
                     /translation="MKISFESVVNNVNNETELILSKEELQIAKRILNTLNENEQSILS
                     SKDILDFCKEALKYNLVPTFV"
     gene            complement(121476..122267)
                     /locus_tag="KRH82_000147"
     CDS             complement(121476..122267)
                     /locus_tag="KRH82_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBG8653455.1"
                     /translation="MNNLQIFEKLEFGQIRMVEVDKKPYFVATDIAKCLGYANTSKAI
                     NDHCRWVTKSYIPHPQNENKILEVNTIPESDMYRLIVNSKLPNAEKFESWVFDEVLPT
                     IRKTGGYIHTTEDMTDDEIMARALQVAQKTIEKKSREIEEKDKVIQLQQPKVLFADAV
                     ASSDDSILVGELAKLLKQNGIDTGEKRLFAWLRDNGYLIKRKGEDYNTPTQKSVDLKI
                     METKKRAIYNPDGSTKITKTPKVTGKGQIYFINKLKLVNQLSMLS"
     gene            complement(122270..122440)
                     /locus_tag="KRH82_000148"
     CDS             complement(122270..122440)
                     /locus_tag="KRH82_000148"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653456.1"
                     /translation="MEKVRMTVRLVPKLNQYVQNIAKECGKSKNSIIVDACWEFIEKI
                     KKENKFNVESEE"
     gene            122561..122872
                     /locus_tag="KRH82_000149"
     CDS             122561..122872
                     /locus_tag="KRH82_000149"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653457.1"
                     /translation="MTTITVRIYTPLNENLEKISYQTGILKSSLILYAINDIIRNSKV
                     NELQSISYKSDDTVRSTLRIPGVLKELLEKTAKENNLSVNSLINNAVHSFCISHWLIY
                     L"
     gene            complement(122858..122995)
                     /locus_tag="KRH82_000150"
     CDS             complement(122858..122995)
                     /locus_tag="KRH82_000150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix domain-containing protein"
                     /protein_id="HBG8653458.1"
                     /translation="MKHEQTTLRIPEDLYKALIDLSKEIGMPIASIVIIACWLYISKI
                     N"
     gene            complement(123050..123838)
                     /locus_tag="KRH82_000151"
     CDS             complement(123050..123838)
                     /locus_tag="KRH82_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBG8653459.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLKSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MEQELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILVGELAKLLRQNGIDTGQNRLFDWLRNNGYLIKRKGEDYNTPTQKSVDLGVI
                     ETKEGTRVHPDGHTSITKTPKITGKGQIYFINKFKSSKQLSMLS"
     gene            complement(123807..124070)
                     /locus_tag="KRH82_000152"
     CDS             complement(123807..124070)
                     /locus_tag="KRH82_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8653460.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNNNEESNHNQAK"
     gene            124249..124644
                     /locus_tag="KRH82_000153"
     CDS             124249..124644
                     /locus_tag="KRH82_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653461.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            complement(124681..124818)
                     /locus_tag="KRH82_000154"
     CDS             complement(124681..124818)
                     /locus_tag="KRH82_000154"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653462.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            125102..125323
                     /locus_tag="KRH82_000155"
     CDS             125102..125323
                     /locus_tag="KRH82_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653463.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNEDKDLTISILI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            125725..126891
                     /locus_tag="KRH82_000156"
     CDS             125725..126891
                     /locus_tag="KRH82_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8653464.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDACVRTINKKLNLDFNFHCL
                     RHTHATLLLENGANIKYIQQRLGHSQLSTTMDTYSHVTSKMESETVDILEGILQ"
     gene            complement(126801..127185)
                     /locus_tag="KRH82_000157"
                     /pseudo
     CDS             complement(126801..127185)
                     /locus_tag="KRH82_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(127425..128819)
                     /locus_tag="KRH82_000158"
     CDS             complement(127425..128819)
                     /locus_tag="KRH82_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBG8653465.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNIPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKGI
                     FNKGNVIWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            complement(128839..129048)
                     /locus_tag="KRH82_000159"
     CDS             complement(128839..129048)
                     /locus_tag="KRH82_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBG8653466.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            complement(129077..130522)
                     /locus_tag="KRH82_000160"
     CDS             complement(129077..130522)
                     /locus_tag="KRH82_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8653467.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            130632..131426
                     /locus_tag="KRH82_000161"
     CDS             130632..131426
                     /locus_tag="KRH82_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBG8653468.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            131477..132799
                     /locus_tag="KRH82_000162"
     CDS             131477..132799
                     /locus_tag="KRH82_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBG8653469.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(132899..134116)
                     /gene="cdeC"
                     /locus_tag="KRH82_000163"
     CDS             complement(132899..134116)
                     /gene="cdeC"
                     /locus_tag="KRH82_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBG8653470.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(134299..134479)
                     /gene="ssrS"
                     /locus_tag="KRH82_000164"
     ncRNA           complement(134299..134479)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRH82_000164"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(134594..135499)
                     /locus_tag="KRH82_000165"
     CDS             complement(134594..135499)
                     /locus_tag="KRH82_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653471.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            135711..136109
                     /locus_tag="KRH82_000166"
     CDS             135711..136109
                     /locus_tag="KRH82_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653472.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            complement(136232..137248)
                     /gene="ccpA"
                     /locus_tag="KRH82_000167"
     CDS             complement(136232..137248)
                     /gene="ccpA"
                     /locus_tag="KRH82_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBG8653473.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(137501..137701)
                     /locus_tag="KRH82_000168"
     CDS             complement(137501..137701)
                     /locus_tag="KRH82_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653474.1"
                     /translation="MLDRFFGEEGGFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            complement(137735..137914)
                     /locus_tag="KRH82_000169"
     CDS             complement(137735..137914)
                     /locus_tag="KRH82_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653475.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            complement(138096..138302)
                     /locus_tag="KRH82_000170"
     CDS             complement(138096..138302)
                     /locus_tag="KRH82_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653476.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            complement(138350..138775)
                     /locus_tag="KRH82_000171"
     CDS             complement(138350..138775)
                     /locus_tag="KRH82_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653477.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            138947..139174
                     /gene="acpP"
                     /locus_tag="KRH82_000172"
     CDS             138947..139174
                     /gene="acpP"
                     /locus_tag="KRH82_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBG8653478.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            complement(139318..140322)
                     /locus_tag="KRH82_000173"
     CDS             complement(139318..140322)
                     /locus_tag="KRH82_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBG8653479.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(140336..141238)
                     /locus_tag="KRH82_000174"
     CDS             complement(140336..141238)
                     /locus_tag="KRH82_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBG8653480.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            complement(141433..142608)
                     /locus_tag="KRH82_000175"
     CDS             complement(141433..142608)
                     /locus_tag="KRH82_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBG8653481.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            complement(142695..143540)
                     /locus_tag="KRH82_000176"
     CDS             complement(142695..143540)
                     /locus_tag="KRH82_000176"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBG8653482.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            complement(143638..144435)
                     /locus_tag="KRH82_000177"
     CDS             complement(143638..144435)
                     /locus_tag="KRH82_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBG8653483.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            complement(144454..145464)
                     /locus_tag="KRH82_000178"
     CDS             complement(144454..145464)
                     /locus_tag="KRH82_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBG8653484.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            complement(145483..146265)
                     /locus_tag="KRH82_000179"
     CDS             complement(145483..146265)
                     /locus_tag="KRH82_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBG8653485.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            complement(146324..147460)
                     /locus_tag="KRH82_000180"
     CDS             complement(146324..147460)
                     /locus_tag="KRH82_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBG8653486.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            complement(148169..148636)
                     /locus_tag="KRH82_000181"
     CDS             complement(148169..148636)
                     /locus_tag="KRH82_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBG8653487.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            complement(148715..149257)
                     /locus_tag="KRH82_000182"
     CDS             complement(148715..149257)
                     /locus_tag="KRH82_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653488.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            complement(149309..149995)
                     /locus_tag="KRH82_000183"
     CDS             complement(149309..149995)
                     /locus_tag="KRH82_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBG8653489.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            complement(149995..150855)
                     /locus_tag="KRH82_000184"
     CDS             complement(149995..150855)
                     /locus_tag="KRH82_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653490.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            150990..151790
                     /locus_tag="KRH82_000185"
     CDS             150990..151790
                     /locus_tag="KRH82_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBG8653491.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            151815..152384
                     /gene="yfcE"
                     /locus_tag="KRH82_000186"
     CDS             151815..152384
                     /gene="yfcE"
                     /locus_tag="KRH82_000186"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBG8653492.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
BASE COUNT        47788 a        27701 c        16458 g        60652 t
ORIGIN      
        1 attttaataa catttaacca gttttttatg taggtaacat ttctacattt ttataaattt
       61 ttttacgttt tttaatttta taattaaaaa tttaaatttt atacatatta taataaattg
      121 tgatatatat aaaataatta aagataaaag gagtatttta tgaacatact tggattaata
      181 gttgaatata acccatttca taatggacac atatatcatt tatctaaatc tatagaaaaa
      241 acaaatgcaa cacatactgt agcaataatg agtggaaatt ttctacaaag aggcgaacca
      301 gctttatttg ataaatacac tagagcaaaa attgctgtcg aaaatggtgt agacttagtt
      361 atagaattac caactttatt tgcttgtcaa agtgctgaaa ttttttctca tggtgctata
      421 acaattttaa attcactaaa ctgcataaat tctatatgtt ttggtagtga agaaggaaat
      481 acagaaattc tttataatat agctgaaatt ttagcaaatg aaccaaatga atttaagtta
      541 cttttaaaaa aatatttaga tgatggtctg ttatttccaa cagctagagc taatgcactt
      601 tttgattata tacatcaaga caaaaaaaat aattttatac aaaattattc aaaggaacaa
      661 ttatcaaaaa cattaaattc atcaaacaac atactgggta tagaatacat aaaaaacctc
      721 atccatttaa acagtagtat aaaaccattt actatctcca gggtccaatc agaatataat
      781 tccgaagaaa ttgagagtga tatttgttct gctactgcta taagaacttc acttaaagaa
      841 aatacagacc tttttcattt aaaaaatgtt attccagaaa aaacttataa catcctaaat
      901 gaaaaaatag ataatggttt tttacctatg tttgatgact tcttctttga tattttaaaa
      961 acaattatac ttagagatat ggacacttta aaagagtatt ttgaagtaaa tgaaggcata
     1021 gaaaacagaa tctataaaga tatctttaca tctgaatttc tacatgaact acaattagca
     1081 attaaatcca agcgatacac tttaaccaaa atcaaacgaa ctctaaacaa tatattgcta
     1141 ggtattaaaa aaagcgacat gcaacttata aaaaacatag atactatacc ttatataaga
     1201 atacttgctt ttaatgataa aggtagagaa attctaaaag agataaaaaa taaatctgaa
     1261 ataaaaataa taaacaagtt ttcaagtata tcattttcat tagatgatac gatttttaaa
     1321 acactcataa gttatgatat aaaagctaca aatatatata atttaatata ttataaaaac
     1381 aataaagatt tagtaaaagg ccctatggat ttttatactc atccaatata tgtaaagtag
     1441 ttttttaaaa taactatatt tataaaaatc attttattaa ctctttatta tataagatac
     1501 aatagtctta ctttatttat gtacacatgc ttttaggatg acaacatcaa cttaaatatt
     1561 atattacttt ctaaatttaa gtaaatattg ccatcctaaa aattttacaa tttagcttca
     1621 gatttaaaag taaagtttaa aatattatat ttaaatctaa tttaatattt tttgttttgt
     1681 aaatattatt aaattaatat ttctaatata ttttccctgg atttaaaata tttttagggt
     1741 caaaagctaa ctttatattt ttaattaaca tcatataagc atctgaattt gattcatgta
     1801 agtactcttt tttagcatat cctatgccat gttcaccaga aacttgacca ctaagttctc
     1861 tagatttttt atacatatag tcaaaagttt cttttaatct tattttccat gtattatcat
     1921 ccataccatc ttttaaaata tatatgtgta gatttccatc tcctgcatga ccaaaacttt
     1981 ttattcttat ttttaatttg tcttgaagct cgtgagtgta tcttataaac tctgctatct
     2041 tatctcttgg aacaacgaca tcacattcat ccatttgtgt cgtagatgcc tttatagctt
     2101 ctaaaaatgc acctctggct gaccatatag aatcgtttct ttcttgtgta tctgatataa
     2161 atacatctaa tgcaccattt tctaaacata aattagctac tttttcatat tctttttcta
     2221 tatcttcagt gctatttcca tcaaatgtaa gcaaaagata agcatctgat gtattatctg
     2281 gaaacttttt acctaaaaat tcttctgctg ccaatattac atctctttcc ataaattcta
     2341 tagccgttgg tattgatttt gattttatta ttttaggaac agtttctatt gccattgata
     2401 aatctggaaa tggtataagc aaacttatac ttttctttgg taaaggaagc aattttaata
     2461 tagctttagt aactattcct aaagtacctt ctgagcccac taataaatcc tttatactat
     2521 atccagaact atttttaacc acctttccac ctacatttat aatttctcca tttggtagta
     2581 caacttcaag acctcttaca taatcccttg taacgccata ttttactgct ctcataccac
     2641 ctgcattagt gtttatatta cctgcaattg tagcactttt ttcacctggg tcaggtgggt
     2701 aaaataaatc tctatcttga acatattgac ctattgtcat caataaaaca cctggttcta
     2761 ctgtcaatgt taaattttca taatcaactt caagtatttt attcatttta catagattaa
     2821 tcattattcc accatttatg gcaacagcag cacctacaag accagtacct tgacctcttg
     2881 gtgtgactgg tatattattt ttatatgcgt atttcattat tttagatact tgttcagttt
     2941 caagtacatt tactaaaact tcagggcact tctcaatccc tccaagttca tcatgtgaaa
     3001 aatcttcatt tatatcactt ccaactaata cattttcttc tccacaagta tctattaaaa
     3061 aatctatatc ttttttatcg attaatttat acatttctat ccccctattt agctgctgat
     3121 gccatatatt tttgattatt atctttgtta ttttctattt tttcaatcaa tttaggaata
     3181 atatcataaa tatcacctat taaagctaaa tgtgctacat caagtatagg cgctttatca
     3241 tctttattta ttgctactat atagtcagca ccctgcatcc ccgcaacaaa ttgaacagct
     3301 ccagatacac cacaagttat tatcaattta ggttttacag ttctaccact aagacctatt
     3361 tgttttttag catctatcca acctgcttct attacaggtc ttgttcctgc cacttgagcg
     3421 tttaacttat cagctaattt atatatcatc tccatatctt cttgtttttt tattgctcta
     3481 cttgccacaa ctatcacttc agcttcttcc agaccaactt ctttattttt ttcttttaca
     3541 ctcagtacct taattttaga ttttagttct tttttttcta ctttacataa agttatcttt
     3601 cctgtagtat tctctatttt ttctggtgct gaaaatattt tatatcttac agtggcaaat
     3661 tgtggtctat tattaggtgt gtttatatga gccattatat ttccaccaaa tgctggtctt
     3721 atttggtcta aatcagtatt tgattgaata tcaagtattg tacaatctgc tgtaagacct
     3781 gttctaaatc tagcggcaag tcttggagct aatgacctac ctaatgtagt tccaccaact
     3841 aatactatcg ttggttttat tttatctata aagttttcta ttgcttttga atatggttct
     3901 atcctaaaat ctttaaattc atcttcatca tatacaaata cttcatccac cccataagaa
     3961 atcaaattac tgcacttatc ttttatgtct tttcctacaa atacacaata cacaggttgt
     4021 tttatttttg atgccatctc acgagcttta cctataagct cgtacgttac aggatgtata
     4081 tttccattat gatgttcaac atatactgca attcccctcc attcatcttt attaatttgt
     4141 actttactac tctctataaa ttcaaatgcg ccttttggtc cacttttgac acacaacttg
     4201 cacatcttac agccagcact tatttctact atacctgact tttcttctat agccccaaaa
     4261 ggacatattt ctaaaattct ctttaagtca gttattttat cttgatttac aactatcttt
     4321 gacatttatt actccccctt acaccaactt taattcctct aatttattta caagtgcaaa
     4381 acttagttca tctgcatttc ctcttacaat atttttatct gtatttggct ttggaggaaa
     4441 tattcttaca acttgagtag gagaaccatt aagtccatag ttattttcat ctttatcttc
     4501 aaagtcatct aagctatata caggtatttc tctatcttta gtattaagtt ttaatttaaa
     4561 tgaaggtagt cttggttgaa aaatgtcttt ttctacagtt attaaacatg gatattcaat
     4621 ctcacatact tgtaaatcat ttggcatatc tatttcaaca actatacttt catctttaac
     4681 ttcaattaat tttgtaacgt tagtaacatg aggtatatct aaaaattcag ctacttcagg
     4741 tcccacctgt gctgtatcac catcagtagt ttgttttcca caaattatta ggtctacctt
     4801 tcccatcttc ttaatacctt gtgatatggt ataggaagta gccaatacat ctgctcctcc
     4861 aaatctccta tcacttatta atgctccttc atcagctccc atcataaaac tttcttcaat
     4921 taccttcttt gcctgaggag gacccatgct aagtactttt agattcgctt tcttctcttc
     4981 ctttattcta agagctgttt ctaaagcata taggtcatag ggattcattt ttgaatctac
     5041 tccatctctt tttagtactc ctgtagtttc atcaacttct actgaagtcg ttccaggaac
     5101 ttgtttaata catgtcaaaa tttccataaa gtacactcct tttttattta actataactg
     5161 atactccatc aggtataact actactttgc tctccttacc aactatacta ttcgccattt
     5221 ctaaagcttc tttaaagtta aatgcatgtt tcatatgcat tttttttatc atttcaggat
     5281 tacacttatc tgttaccatt atcacagtat atttagataa tattctcgct agtatctgaa
     5341 attcccattg gtctggaatc gtatctactc tatcgacact tctaatttta tctaaaagtt
     5401 gttttggaga atctgcattt gctacatttt cataaaaaga ttgacctcca tgaccatcat
     5461 tacatgctga aatcattatt attactccac cgtctttaca agtagcttca gctgctgtca
     5521 ttcctttaac agattgataa atattttggt ctagtggata tccaccattt gtagttacaa
     5581 caatatcaga ttttatagaa tttacttttg ataactctgt tacaaatcta catcctttag
     5641 tatgtgcttt ttcgacatca ccagcaaagg aagcaattat ttttttatct ttatctatta
     5701 caacattcaa tatgaatgct aattttgcaa ctttagctgc atataccata tcctcatgaa
     5761 taggattatt attcaatttt ccagttcttg aattatcact atctataaag tcactacagt
     5821 gattgtacat tatagtcttt gcagatgcga ttcctggaag tacgcttttt ctgccacctg
     5881 aaaaacctgc aaagaaatga ggttctataa aaccttctgc tatcaaaagt tctgcctcat
     5941 atgctagttt gtttatatat aaatctccac ctgaaggcaa tatccctact ttacacatag
     6001 atttatcatc agtagatata tgcataacta tatcttcatt atctactatt tcttctccca
     6061 ttttataaat tagctcttcc cttgtacttg gcctatgaaa tccagttgcc actataatct
     6121 tcacatcaat ttctggatta acattcctaa tccttcttaa tataattggc atagttattc
     6181 tacttggtac aggtcttgta tggtcacttg taattatgac tacattcttt ttccccttaa
     6241 ccagttcttc cagagaatta gagcctatag gattattcat agattcttca actatctctt
     6301 cttgagtctt atgttctata taattatccg attttgactc caaaacaccg agaaaacgtt
     6361 catcaggtat ttctaaaatc attccttgtt ttgaatacgg tacttttaac tttaccattt
     6421 ttaatctccc attataataa actataaaat tggtatgtgg tcataccagt tttacattta
     6481 tatgatagta ccattatcta ccatttgcaa gaataattta ttttataaca aacttttaat
     6541 tttcattttt tctataattt ttacttataa aatccatatg ttcctttgct ttatcacatg
     6601 caagttctac atcattttct acaactgcat tgtatatagc ttcatgctgt ttaagcaata
     6661 tattttcatt aaaaggttct gcgattattt tttctcttgc atcttctata aatccatcaa
     6721 ataattttga tgctgtcata aaaagacttt gaattaaata atttttactt aatgttgcta
     6781 gtttactgtg aaatttttgg tctaataaca ccagtactcg attattatct tttttattag
     6841 tttctaccct catttcatct attatatgtt tcaattctat aacttcagaa gaagttattc
     6901 tctttgaagc aagttttgca atctcaattt ctaggattat tctaagctct aatatatctt
     6961 caagtgtacc attattaagt ttaaaaatca tagataaagg ttctattaaa gttttttcta
     7021 tatttgtaca tataaaattt ccttcaccct gtctgctttc tatcactccc atagtctcta
     7081 ataccctaat agcttccctt atggaagttc tactcacatt catttgttca gacagttctc
     7141 tttctgatag taatttatcc ccctttttta actctccatt tagtatttta tattgtattt
     7201 gctcaattac ttgttcataa acttttttac tagctatact attaaacatt ttttcctcca
     7261 atatgataat cgttgttgta atatatatct attatatatc ttaagccatt acattcatat
     7321 atttttatta cttttaatat aatatcttat aactcaaatt tacaggtgat attatgaaaa
     7381 aaaataaaat tattgctttt tttgctccat ctatcatagt tggagttcta gttttaggga
     7441 ttatcctata cccaaatgaa gctataaaat ctgcaagaga aggcttttct atatggtcta
     7501 atgttttagt tccatcacta ctaccattta taattggagc aaacttaatt gttgatttaa
     7561 aaatagtgga tattataggg tttatcatca atcccataac tagatttgta tttaatgttt
     7621 caggaaagag cgctttagct tttgctatat ctacagtatc tggttatcca gtaggagtaa
     7681 gtttagcttc tgaatttagg agtaatggac aaatttctaa gtatgaagca caaagacttg
     7741 tgtctttttg ttctacatca ggacctttat tcataatagg ttcggttggt acaggtatgt
     7801 tccaaaattc aaacttaggt tatttaatga ttctctgcca ttatctagga actatattgg
     7861 ttggtctttt ctttagaaat tatggtaatg aaaaccttcc aaagacaaaa ttggatttaa
     7921 aaacaaatat aaaaaatgta atcaacatta gaaattcaag tgggaatggt ttttttgttt
     7981 tatttggaaa tgctgtattt aatggagtaa atacattact tacagttggt ggatttgtaa
     8041 ttgttttttc agtagtattt aaaatactat ctctttttaa tgtaatctca ttaatagcat
     8101 cagttatata tttgcctctt tcatttttag gtgttagtaa agaactctgt caagcatttg
     8161 taagtggtct atttgaaatt actataggat gcaataaagt atctagtata acaagttctc
     8221 cagaaatttt aagagcatct ttagctagtt ttttgatagg atttagtgga ttatccatcc
     8281 tagctcaatg ttgtacattt ctatcaaaaa cggacataga tttaaaatta tacatactaa
     8341 gtaaatttgc gcatggagtt ttagctgcta tctttatatt tatactttat ccaattgcaa
     8401 actctgctgt gttggtttct agctttgctg atacatacaa cgttatatat aataatttaa
     8461 tctggtttta ttaccttagc tattatgata caattattca aattgtagta ataatttatc
     8521 taatctcagc cgtatttatt gcaaaaaaac atatgaaaac tttatctaca aatgggaaac
     8581 taatgcgata taaaaatact tttttcacta agaaattttc acgaaaaaaa taaaactaat
     8641 aaaacttaac taaatacttc cattttttta ttatatttgt cataatttta ataacctttt
     8701 taattagttt aacagcatag ttatttcatc acaatttaat aattttatta gaaatatttt
     8761 tcaaaaaatt ctccttaatc acatatatca cacttgtata agtttactgg gaaatttttc
     8821 cattatataa tatttcattt atattatata ataaataccg acctaaactt accaaatcaa
     8881 actaagagga gtggttgaaa atggcaacaa gacctataga aatagacgaa tataaaaaga
     8941 taatggaact attacatact ggctttactt atagtgaaaa tggcgttgaa aaaagattta
     9001 gaaaaaatcc taaagttgca ttggcactaa tgttagaagc taatttaggt ctaagaatat
     9061 cagatatttt aagattaaag ataggtaatt ttaaaggtaa tatgttggaa ataaatgaaa
     9121 aaaagacggg caaattacag tatagaccag ttaataaaaa tataattgag tccataaatg
     9181 aacatgcaag aaagtataat cttaaatcaa atgactactt agtaaatata aagacaaagg
     9241 ctattcaaaa acagttgagg ataatttgta aatacttaaa tctgtataat ataagtacac
     9301 atagctttag aaagctctat gctactactc aatttgaaaa gagtaacaat aatttagagt
     9361 tggttaaaga acttttaaat cacagctctg tagccactac acagcgatat ataagggtaa
     9421 ctcagcaagc tattaatgaa gctagtgaaa atttctttat tggttaatta taacgtatac
     9481 atttttctat tatcttatta attcaccaga tattaaaaaa gagtgtctca aaatgaactt
     9541 tttagttcat gagacactct ttttttataa aatcaaatat atttttatta tttcaacact
     9601 ggaaaaaagg cttatctctc tattttgaga caccctatta aattttcata attcttgcat
     9661 aaacatatta atctatcttc aataattttt tagctgattc actgtaatta tttcttttta
     9721 caatttccaa aactctatca atctcatgtt ctgactttgc acttacaaaa atcgccaatt
     9781 cttcatcatc tataatatca taactatcta catatttatc taaacattct aaaattccat
     9841 ctttattatt atacccacca aatctaacta ctgcactaca ctcatcttct ataagtccac
     9901 ttaaatccaa tttccctttt gaaaaagact ttatatttga acttctatta tctattatat
     9961 ctataatatc tgcataaaca gcacttcctg ttgcacctct tccagctccc ttacctacaa
    10021 aagaaagttc acctactgaa tcacctacta aaataactac gttgaactca ttatctatct
    10081 ttgaaagcat attattattg tccactaatg ctggtctaac aaatccactt acttctcctg
    10141 attcatactt acttctagca accaatttta tcttacaatt taattttttt gcatattcta
    10201 tatctttttc atctattgaa gttattcctt ctaataataa atctttccaa tatactattt
    10261 ttccataaga taaagtagac aatatagata actttctagc actatcatat cctaaaacat
    10321 ctgcatctgg attaacttct gcaaatccca actcttgtgc ctgttttaaa gcgacatcat
    10381 acggtaaatt ttcatcatac atctttgata atataaaatt acaagtccca tttaaaatag
    10441 cgtttatgct ctttatattg ttgccttcca gtgattctat caatggtttt aaaactggaa
    10501 taccacctgc cacagatgct tcaaacttga tgctaacatt atttaagtta gctaattcta
    10561 taaggtcact acctttttca gccagtaaat ctttattagc tgtcactaca tgtatttttt
    10621 tatttaacgc tcttgttaca taatcaaaag ctggatttaa tcctccaatt acttcaacta
    10681 gtatatcaat atccttgtca aatatatctt ctatatcagt agttatctta tcaaagtact
    10741 tcttatactt gtgtttttct ttatttttaa ctaaaattcc aacaacttct atatctcttt
    10801 ttgaagtatt attttctatt aaatcaatta atccacttcc tactgttcca taccctaata
    10861 ttgctatctt cactgtaaca tacccccatc attttgatta tattaaatta tttatatata
    10921 taaatatacc aataaaaaaa gcttgagtat aaactcaagc catatgacgg gtttatactc
    10981 atctttcagc ataaatgctg caggatttag caccaatgta taattaaata tactggttgc
    11041 cgggcttcac agggccagtc cctctgccac tcttgataag attgctaatt taaatttatg
    11101 tttaatagta taatacaatt tcttccaatt gtcactattt ttttaactta tttccctaaa
    11161 aggatataaa ctattatcta acagctcttt tagttggttt accctttttt gtaacattat
    11221 tatttttagt ctttgctttc gcttgttcat gtcctggaaa aagtatttta ggctcttcaa
    11281 tattcctctt gtaaatagta aatttaaaac caatagcctg cacaaattca gctcttaaag
    11341 cttcacatac tgcattagca gtttctttag tatcaagacc tgcattttct aatatagtaa
    11401 cttttactaa ttctctagtt cttaacatac catctaattg ctctaagaaa ctctctgtaa
    11461 caccttcttt accaatttgt gtagtaggct ttaaagtatt tgccaaagat cttaaatacg
    11521 ccctttgttt tccttttaac atattctcac ctctataatt ctatacttaa attatctata
    11581 atctatattt aaattaattg taaaactcaa attctaattc ataaatttta accacatctc
    11641 catcttctat tcccatttct ctaagtctat caaaaacacc ttgactctcc atagcttttt
    11701 ggaaatattg aagggattcc atatcatcaa aatttacaga atacattatt cttctaagtg
    11761 ctttacctgt aactacatac acaccatctt caatatctat acttaactct tcttcagtac
    11821 caatatcaag ttctggtcta tacatttctt cttctgaaac tagctccaca tcttctactt
    11881 cttttagcat tttagaaaca taggctatta cttcatctat gccttgacga gttgctgctg
    11941 acattttaaa tactgtatat cctctgcctt ctaattcact cttaaacttc tcaaacttac
    12001 tctcatcttc taatatatca aatttatttg caactacaac ttgtggtctc tttgaaagct
    12061 tttcattgta caatttaagc tcatcattta tcttgtcaaa atcttcaata gggtctcttc
    12121 cctctaatcc agatatatct acaatatgta tcaatacctt tgttctctca acatgtctta
    12181 agaactcatg acctaatcct atgccttcag aagcaccctc tataattcca ggtatatctg
    12241 caagtacaaa actatctcca aacttagttt gaacaacacc tagatttggt gtaagtgttg
    12301 taaaatgata gtttgcaatt ttgggtttag ctttagttac aactgataga aatgttgatt
    12361 tacctacatt tggaaatcct aaaagaccaa catctgctat cattttaagt tcaagagtta
    12421 tccatctttc ttctccatct gtaccagatt ttgcaaaagc tggagcttgt cttactgcat
    12481 ttgcaaagtg ttggttacct ttaccaccta taccaccttt tgcaactata gctgtatctc
    12541 cttctttttt taaatctgct aatacaagac ctgtagcctc atctcttatt actgtacctg
    12601 ctggtacttt taatactaaa ttttctccat ttttaccagc tctttttcct ttgcttccgt
    12661 cgccaccatt ttgagcttga tattttttct ggtacttaaa gtccattaga gttctaagcc
    12721 ccaaatcaac ttcaaatatg atgcttgctc cacgaccacc atctccaccg tctggaccac
    12781 cagctggaac gtatttttct cttctaaatg ctaccgaacc atttccacca tttccagcct
    12841 taacaaatat tcttgcctta tctataaaca aattcttcac ctacttaatt aaaaactttt
    12901 aattagcatt accaaaaata ccattataaa ttcatcagta ttataagaaa aaggagtgcc
    12961 tcaacactcc ttttatgtat attactcagc tattgctact ggatatatac taactttttt
    13021 tctcttcttg tcttttcttt cgaatttaac agtaccatca actaatgcaa ataaagtatc
    13081 atcactacct tttccaacat tagttcctgg atgtatttta gttcctcttt gtctaactat
    13141 tatacttcca gcagttacta attgaccatc gaatctctta acacctaatc ttttagatat
    13201 agaatctcta ccatttttag aagaacctac ccctttttta gatgctaata attgtaaatt
    13261 catgtttaac atatggagtc accccctact tttttaaaat ttttatattt tttgggtatt
    13321 cccgtttaat ttctttaacc gctaattgaa agtgatttag taataattgt gcgtctttta
    13381 catgtgtatc tttgactata cactctatat gaccttcttc tcctactact ttttcaaatt
    13441 caatcttctg taatttgtct aaagaattta taactgcaat agcattagat gtaactgcag
    13501 cacatactat atcatagcct atttcagcaa aatcagcatg tccctttaaa caaaaacctt
    13561 gcaacaagaa atcatcatta taataatatt taacttttat cataacttaa ccaataacta
    13621 agcgtttatt ttttctacaa ctatcttagt gtatgattga cgatgtcctt gttttcttct
    13681 gtaatctttt tttgctttat acttgaaaac tataactttc ttagctttac cttgttcaac
    13741 aactttagct tgaacagatg ctccttctac tactggagaa cctaatttta attctccatc
    13801 tttagagcaa gctaatactt cgtttaaagt aacaacatca cctgcgttag cttctaattt
    13861 ttcaacgaat aatacatcac cttcagaaac tttatattgc tttccaccag tctttactat
    13921 agcgtacatt aaatacacct cctcggcctc aaactcgcca gtacaaggta cttcatttga
    13981 agatttaaac ctttactgtg cggcattaca attattaatt ataaaatatt tacattttat
    14041 tgtcaactat tttatcgaaa ataacattgg ttttattgtg ctttaatgta ctatttgcgt
    14101 ttaaagaaat ctttatatta tatttttcac caattttatc aattatatcc atataatatt
    14161 cttttatttg ttcaaaaata aaatcattaa attctaccat tatgtttttg taaacagtat
    14221 gttcacttat tctcataatt tctttttcaa tactatctag tatataatgt acagatttta
    14281 ttgtttgttc accatcacaa catggacaag acattaaata atacttatca atggattctt
    14341 tttctctacg cctagcaact tctactaaac caagttttgt catacctaat acttcagctt
    14401 ttcttttatc tttattaaat tcttcttcta ggatgtgtaa aatctccttt tgatgcttct
    14461 ttttatgcat atcaataaaa tcgattatta ttatcccagc tatgtctcta attctaagct
    14521 gtcttacaat ttcttttgca gcttcaagat tagttttata aacggtttca tcaagtttac
    14581 cagttccaat aaacttaccc gtatttacat ctataaccgt aagagcttct gttttttcaa
    14641 ttattaaata acctccactc tttaaccata cttttttatt taataatttt tctattttag
    14701 attctattct gtataaatca aatacatctc tattttcctc aagacacagt ttatcaacat
    14761 aagtcttatc tatacctctt aaaatagact taagttcaga gtacttatca taactattgg
    14821 taattataga ttcaatatca tcattcacat tatcttttac atatttagtt gcaaaatcta
    14881 aagacttata taataatttc ggacctatac caagtttata ttcttttaaa atgttttcat
    14941 actttaattt caactcttct atatctttct ttatttcatc atgagtgcaa ccttgagcct
    15001 cagtccttat tattaatcct agattttcct tatttactgc cttagtaatt ttttttaatc
    15061 taaatcgttc tttttcatca gtaattttat ttgatattgt agttctatca ttggaaggta
    15121 tatagacaat ataccttcca gaaatactaa tctcagtgtt taattttgcg cctttagttc
    15181 ctatttcttc tttatttatc tgaaccaaaa tatcctgacc agattttata gtacttccct
    15241 tttttaattg taaataagca agtttcttaa atccaatatc tacaaaacaa gcttctattc
    15301 ctggtataac tttttttacg attccacgat atatattgga tacagtcttc ttatttaaat
    15361 tgtcttcaac aaaaagttct gttaatcttt catcttcaag tactgctgtt ttctgggacc
    15421 ctattaggga ctcaataact atctttttca caacttcacc tctcgagctt acataggagt
    15481 cactaattcc ccatcttcta atacatataa atctcttctc aatatatcaa catctaatgg
    15541 gtcaatatca agttcaaaca tctctaatat ctttggtata agtatattag tatttaaatt
    15601 agtttttgag cctgtagcta tagtagcagt aagagtaata tgttcatctt ctaaatttaa
    15661 aacatcaaag gttcttatca taggtcttat atctacttca accatcttac cttttttatt
    15721 cttttttgtt atgattattt ctttattatt cataaagtca attacttttc tttttacaaa
    15781 ctctttcgtc ataggtcttt tcaaatctat attaaacaaa tattctccat agtctatcac
    15841 agaagaaaga gaaggtgttt gtctatcaat ttcttttgct ttgataaaat ctatcccatc
    15901 tggaagttga attgatactt tatttaaaaa ttcctctact gataaatcat cttcttctat
    15961 ttcaatatct acatactcac cttgactttc tgtccctaaa gccaaagcat tgccataact
    16021 cattttaggg tgaggattaa atccttgaga atgtgataag tttatttcag ctcttctaaa
    16081 cgctctttgt aacaatctct gaaggtcaag atgtgatata tatatcatgt cgccttcctt
    16141 tttaaatttt actcttatta tcttactcat attagcaaag cccccttcct atatcatgta
    16201 tatttattcc acaaccattg cagttatgtc tacaatcaga agtgattttt tcttttttag
    16261 cattttcgtc ttctctaatt aagaattttt tactaatacc tacatctata tggtcccaag
    16321 gaaatacctc ttcatagttt ctatttctat gtgcataaaa atctatagaa agattattct
    16381 tttccatagc ttctttccat atatctaaat taaaatgttc tgcccatcca tcaaatttag
    16441 cacctagtct aaatgcatca tatataactt ttcctattct tctatcgcct ctagctacta
    16501 ctgcttccat caaactagtc tttgaatcat gataattgta ttttatattg ttatttctta
    16561 atttatttac taaatgtctc tgcttattaa taacttcttc tgtagtatct tgaccatgcc
    16621 attggaaagg tgtaaatggc tttggtacaa atgtagaagt actcactgta acactaaaac
    16681 ttctctttag ctttcctcca tttacttttc tataaatatc aataacttta taagctaatt
    16741 tagctatacc atctaaatct tcataagtct cagttggtaa accaatcata aaatacaact
    16801 taacactatt ccaccccatc tcaaaagctc tttctgttgc attttccaaa tcttcttctg
    16861 taacaccttt atttataaca tctctaagtc tttgagttcc tgcttctgga gcaaaagtaa
    16921 gtccagattt tcttacttgt tgtattttat cagcaatttc cattgaaaaa ttatctaatc
    16981 taagggatgg aagcgaaatc ccaatattat tagatgcata ttcatctacc aaataatcag
    17041 tcaactctga taacttacta taatcactcg tactaagtga tgataatgat atttcatcat
    17101 atccagtatt cttaactaat ttatctaata tttctttaag tcttttaaca ctcttttctc
    17161 ttattggtct gtatatcata cctgcttgac agaatctaca tcctctagta catcctctaa
    17221 ataattctag tactattcta tcatgaacag tatctatata aggtactatt agtttttctg
    17281 gataatctac agtctcaaca tcttttatta tccttttagt aggattttta gtaatccctt
    17341 ctctattagg agttacactt tgaactgtac catcttcatt gtacttgaca tcataaaaac
    17401 ttggtatgta tactccttct atgctagata ttttatataa aaaatcttct ctagtcgttt
    17461 tatttttctt ccattcttta tactcattta ctacttctaa attaacctct tcaccttcac
    17521 ctaatattac tacatctaca aaatctgcta atggttcgga attataagca caaggaccac
    17581 caaccattat aaatgggtct tccaaagttc tttcttcttt taatattggt atattggcta
    17641 aatctaatat atttaagata ttagtgtatg aaagttcata ttgaagtgta aaagtgacaa
    17701 aatcaaagtt tgttataggc tctcttgact ctaatgcaaa taatggtata cttttttctc
    17761 tcattatatt ttccatatca actgcaggag aatacactct ctcacaaaat acatcttcat
    17821 ccttatttat tacatcatat aatatatgac tccctaagtg actcatacca acttcatata
    17881 aatctggaaa gcaatgtgca tatcttatca attcactatt actagtatct ttatgaattg
    17941 aatttatttc atttccaaga tatctagcag gcttttctac tttttttaag atttttttca
    18001 agtctacttt attcatttat taaaattcct ccaaacaagc tctttatttt tattcttatt
    18061 tataagtaat attatacacg ataaaatatt ttctatcaaa aatataacta aaatattgaa
    18121 tttaaaatac atattattca caaaatagaa tagctaaaaa tatttaagaa tattttctat
    18181 taaattttta ttgaaataca atttttttac aaagtatgat atattataaa cataaaacta
    18241 ttgttttaca tgacttatca tgacatcttt tgtttcattc acctcaaaat ggggtatgtt
    18301 acttatataa tgataaattt taggagggtt aaaaatgagt aaagtttttg aagtaaaaaa
    18361 agatatctac tttactggcg tagtagatga aggtttaaaa gtattcgaca taataatgga
    18421 aactgagttt gggacaactt acaactctta tttaatcaag gacgaaaaaa cggttttatt
    18481 tgacactgta aaggcaaatt ttaaagatga gtttttaagt aatttatcag aggttactga
    18541 tatagctaaa attgactatg ttgtaattca tcacacagaa ccagaccatg caggtagttt
    18601 aaaatactta ttagatataa atcctaatat agaagtttat tgtactaaag ctgccaaact
    18661 atacttagat ggtcaaataa atagaccttt taactgtcat gtaataaaag atggtgaaat
    18721 tttaaatatc ggtaaaagaa atcttagatt tataactgct ccattcttac attgggttga
    18781 tacaatgttt acttacattg aggaggacaa gactctttta acttgtgatg catttggttg
    18841 tcactttgca agtgttgatg cagaggtagt gaatagtgaa gattatctaa aatcagctaa
    18901 acactactat gattgtatag ttaagccatt tgctaaacat gttttaagtg ctgtagataa
    18961 ggtggtagga ctaaacatag aatttgatac tatattgact tctcatggtc caatgcttac
    19021 taaagaccca atggctgctg ttaaaagata tgttgagtgg tctacagaag ctgttaatac
    19081 aactaatcaa aatcaagttt ctatattcta cttatcagct tatagtaata ctttagagat
    19141 ggctaaaaag ataaaagaag gacttgataa agaaggtgca aaggctgaat tatatgattt
    19201 agaagatatg acattaacag aaatgcacga tacattagta gtgtcaaaag taatattact
    19261 aggctctcca actataaaca aaactatggt taaacctatg tgggatttat tctctgttat
    19321 agacccaatg gctaaccaag gcaagatagc aggagtattt ggttcatttg gttggagtgg
    19381 tgaaggtata actatggctg agactttact taaatctatg tcattcaaaa tgcctgtaga
    19441 atctcttaag aaaaaattct tccctagtga agagacatta aaagagtgta tggcatttgg
    19501 tgcagaattt gcaaaattag ttaaatagcc attaatcaca cataatatta tttaaaataa
    19561 atgattttat atttaaaaat aaattaaaaa ggagttgtct caaaattaat ttttctaatc
    19621 taattttaag ttcaactcct tttttatttt ctaaaatgac tgatataatg ataaatgcac
    19681 cctttgtgcg agggtgcatt atttataata tgttctattt gtacactagt atatttgtat
    19741 taattcacat atctagcgta tgctaccatc cctcttccag aattagatgc cgtttcacca
    19801 atttccactt taataattac attattttct ttacactttt ttgataattc tgctgcagaa
    19861 aggttcttac cagtaaaatc taaagaaaat ggcttatcat attcaaaagg atactcatca
    19921 ggtacaccat ctggagctaa tgcaaccata ccatatggtg tattcataaa ccctattaca
    19981 gtaactgtat gctttgatgg gtctaaattt gaatttttgc ttgtaaactt aattgtattt
    20041 attgatgagt tgattaaact acacggaact ccctcataca tttcaatttt tggacgtaga
    20101 ttatttccat aaacttcatc aagtattgcc ccttgttgat ctgctatcat agtgtgattc
    20161 ccaggtccaa ctggcgcaga aggcttagct ggcgtaggtt tcttaacagt tggcgttgga
    20221 ttctgtgtct ttactacttc gccaacagct ggatatgctt tcttgtcaaa tggtaatggg
    20281 tgagtaagac tcttgtatat gatgtctgct cctgctgatt tgttggcatc aatatctaca
    20341 tgatacaaac gtccatcctc aaaacgaata agattccact gatggtcatt tgttgtacta
    20401 tgtacataat aacattcaat tcccatagca tcacataaag ctttcaagct cctacacatt
    20461 ccagaacaag cacctttttt agtaaccaat gtataagcag tattggctcc ctctgctgcg
    20521 ttccagttaa catatgttgt gttgttttta atgtgattat gtatagatac aatccactat
    20581 ggagaaatat aaaagaaaag agtataacaa acaataaaaa ataagatgat tcaaatttta
    20641 ttttgaaaca tcttatttac tctacaaatt aagattattt ggtgaattat ttaattatta
    20701 ttttttatta aagaaatttt aaatcttaat ataaaatacg ctattataca taataatcca
    20761 aatgcaaatg ctactggaat taacatctcc gattcaaaat aaaagaaata ttctaagaaa
    20821 atatctggat ttactatatt cccattcttg tctaaaaaat cttttccatt atatcctaaa
    20881 tgctgtataa aattacttat gttattataa tctgcttccc tctcatatac catattagca
    20941 ttcaatcctg aagaacttaa attagtgttt ccatctttca tatctattac atatagtcta
    21001 agagctttga ctttactata cttatcttta tcaagtattt tttcaagttc taacttatat
    21061 tcaccaatct ttgtcatatc atgtctttct gccaattgct ttatttctcc atcaagttct
    21121 tttcctaaat tatacatatt atgttgtaaa ctattattgt aataccacat aaatccagaa
    21181 attaaaaatg caattatact tatgtaacct aatacttttt taaaccccat tacaattgat
    21241 ttatgcctat ccaatgataa agatagttct tttattatat tacataattc atactgcatt
    21301 tcatcaccat catcaaatct ttcaattgct tttttacatg cttcttcttc atctaatcct
    21361 tctaatttaa attcatttgc agattctata agatggcatc tcatttcctg ttttaattct
    21421 atagtacttt tattgtcaca ttttttatat agtttatcta aatattcatc tattagtttc
    21481 ataaattaat ccacctctcc caaaaattga ttcataacct ttttaataaa tctccattct
    21541 tgtttcttta tttctaaaaa atctttacct tcattagtta aattataata ttttcttctt
    21601 ccacctgaac tttgttcatt gctataataa gatttaatta aatttttaga ttccattctt
    21661 ttaagtgcaa gatacattgt tccttctttt aattcaaact cacttctttc tcttacttgc
    21721 tttgcaattt catatccata acaatctttc ttttctaata tagaaacaat taatatatcg
    21781 atataacctt ttaacacttc tttatttaac tgcattatgt accaccgcct tttcacctac
    21841 tactctataa tgtatagtac ttatatttac tataatatta catagtactc tataatgcaa
    21901 ggtttatatt ctaaaataga ctcaaaaata ataaatagct gtatattaat atttaatcta
    21961 taaatactaa tatacagcta tttatcaaat tttaaaaata aatttttgtt ttattaatgt
    22021 tgtcataaca acatttactt gattgaaata gtattaccta taagtttaaa tatatataat
    22081 aatagacttg attctatttc atattattaa aatagagtaa tagttaaatt ctactactct
    22141 atctataatc tatttcctaa ttatttaatc tcaaatttag ctcttcatca tttaaatctt
    22201 tcataagatt tctacaggta ctaggtttat tccaacagaa agactagggc attaaacact
    22261 tatatatctg tttctttaga ctgtaatatt aatatttttt aaatacgttg acttttgctt
    22321 tttctaactt ctctccatga tagttctcct ctatcaagag cttttataaa tatttctgct
    22381 gaagctagat ttgtagctat tggaacatga taaacatcac aaagtcttat taacgcttgt
    22441 atatctgttt catgagcctg agatgtcaat gggtctctta aaaaaataac taaatctatt
    22501 tcttgtgtta ctattaaaga acctatttgt tggtctccac ctaaaggacc agatgctaat
    22561 ctatttatat ttaattcagt ttcatccatt attctttttc ctgtagttcc agttgcatat
    22621 agtccatact tttttaaaat tgattcataa cctatacaaa atccgaccat agtgtttttc
    22681 atttggtcat gtgctactaa tgctatattc atatatctaa tctcctcaat ttatgtttag
    22741 atgtatttaa atttagaaat ttattttctt tcttctcata cacacattta gtactaatcc
    22801 taagtttgct aaagatgtca ataacgaact tcctccataa cttacaaaag gtaatgttac
    22861 tccagttact ggtattaacg caaccgtcat acctatattt tggattatct ggtaaccaaa
    22921 cattcccata acaccaacca ctatgagggt tccataaaaa tcttttgcat ctcttgcaat
    22981 tgctaaaagc cttaatagga atatcataaa taagattatc aacactgcca ttcctattac
    23041 accaagttct tcacctacaa cagcaaatat aaaatcacta tcttgtacag gtaaaaaatc
    23101 ttcttgattt tgacttccat tgtaaagtcc tttaccagtt acgcctccag aaccaattgc
    23161 aatcagagat tgcataactt gatagtttcc ttttagagtt acatcttctg gatttagaaa
    23221 agcttctatt cttacctttt gatggtctgc catcattaaa tacatcagtg gcattgacac
    23281 taatagtatg attattcctc tttttatcaa ctttgagcta agacctgctg tgaacagcat
    23341 tgcaaatatc atacaacaaa atacaattcc tgttcccaag tctggttgtg caatcaataa
    23401 tccgataaat ggaagagaat aaactacaac aggcataact tcctttaacg tatttaattt
    23461 atcctttttg gattcaagta tctttgcata acttagtaca aatgttaatt tgactatttc
    23521 agatgtctgc aagtcaagtg gtcctaagtt aatccacgac ctagctccac cttttactgt
    23581 cccaattcca ggtaataaaa ctatggctaa caaaataaga cttattatat aaagcgcttt
    23641 ataatacctg cctagaaggt tatagtcaaa aaataatatg actataatca ttcctatccc
    23701 aagtacaaaa gctaatcctt gtttaatcaa ttgattatat gaacctgttg aattagcatg
    23761 tgttgcacta ctaagtataa caagcccaaa aataaagata gctaatactg taactataag
    23821 tttccagtct aactgtttta tcaacttaat tgtcgactta taattaatat tgattttttt
    23881 caaagaatca ccgtctttct atctttaaac atataattaa ataaaagggg catataccaa
    23941 taaggatatc ccccttttaa gcactaatta catacatcta tcttttatat tctttagtgg
    24001 tatattagca actaatgcag atacaggttt gtcatcatgc tcacctctgc atttagacat
    24061 ttttatttca agaccatcat cttctatttc tgcataatta gctattactt tcaaaatgtc
    24121 tgtttttatc atctctaaaa gttgtggtga acaatctact ctatcatgaa ctaaaactag
    24181 ctttaacctc tctttagcaa cagatttact agttttagcc tcgttagaaa aaactctaaa
    24241 taaatctaac acagatgtat cctcctttgc tacttagcca tgctaaacat ttttttaagt
    24301 ctaccaaaga atccatcttc aacttcaaga tcaagtagag gaacttcttc atttagtatc
    24361 ctttttgcga tatttttgta tgcttgacca gcaagtgact tagaatcaag tatagctggc
    24421 tctcctttat ttgttgatat aattatgctt tcatcatcag gaacaagacc taacaaatct
    24481 attgctaata tttctattat atcttgttta tccatcatgt ctccacgctt aaccatatca
    24541 tttctaattc tatttataac taatcttatc tcttttattt catttgcttc taatagacct
    24601 attattctat cagcatctct tactgctgat atttctggat tagtaactac aatagctcta
    24661 tctgctccag ctactgcatt tttaaagcct tgctcaatac ctgctggaca gtctattatt
    24721 atatactcga aagattcttt tagtttctca cacaggtcaa tcatctgctc aactgagaca
    24781 gcatttttat ctctagtttg tgctgctggt aataaatata gattatcaaa tcttttgtct
    24841 tttattagag cttgcttaag cctacaagtt ccttcaacta catctactat gtcataaact
    24901 attcgatttt caagacccat tactacatct aagtttctaa gtccaatatc tgcatccaca
    24961 actactgttt ttttattttc taggcttagc gcagttccta agtttgctgc ggtagtagtt
    25021 tttccaaccc cacctttacc agatgttata actataactt cgctcataat actaccccct
    25081 atttttcttt ctatttgtct aactttgaca aatagctttc gattacaatt cttccattac
    25141 ttacaaaggc tatttctggg ctaatttctg attcactttc ataattttct tcatcatctg
    25201 gagcttctgc aatattatct gctatttgta atattttagg attaagattt ccagcaacaa
    25261 catatgcaaa ttcattgcct tctgcacctg catgtacaaa accttctatt ttacccatta
    25321 caaaaacatt acctcctgct acaaccttag caccagcatt tatatctccc ataacaactg
    25381 tatttgattt tgaaaggact tttgaaccag gtttcatatc attcaatata actacatcac
    25441 cttcaaattc aatattttca ccagatctta gggtattgac atattttgtt ggaaaattac
    25501 tattttcttc aattttttga tcttcaacaa attccacatc aaatctagaa gtaattcctt
    25561 ctttaagttc tagaatctcc atgtcagtta aacaatcact attaatttta ctaattttag
    25621 ccccattaaa aaagccaaca tatgcttcca atttgtttat tattttttcc tgtatttcct
    25681 caaatggagc ttctcttttt atatttacta ttatccctct tttattaccc ttgaactcta
    25741 ctagttcttg actacaaatt tctcttaaag acataacaac ctccagagtg atatatcatt
    25801 tatattcttc aaatacgctt taaacccttt tattttttct atataaagct aaagtttata
    25861 catagattga gctatctatt aatttgtgac tcgaaattta tattttcgtc agaagaattg
    25921 ttaacatcat tcgtcttgtt gtcattttta ctattagttg gctctaatcc catataagtt
    25981 ccaataactt ctctagttgg taaaagtgag aatacacttg aatcaccttg aggaattaca
    26041 catacaacag ctatttctgg gtcatctgct ggagcaaaag caacagtcca cgtaaaagaa
    26101 ccataatctt gtttaaatct atctatttgg tcatctgtta tttttggatt taattctttt
    26161 atagcttttc ttagatatga agaattcacc ttatcagtgt cctctaatct aacttttact
    26221 ccatcttcta attcttcctc taatttcttt ctttcttcgt ctttcaaatc tttattttct
    26281 aatttctttt ttatttcctt ttccttagct aatgaaagct ctttttcttt ttctgctttc
    26341 atcttatcag ctagtttaat cgcatcattt aggttgacat tataagatga catatgactt
    26401 tttaaatatt catactcgtt atctgtaggt attttcccac ttttctcagc tgtaccagtt
    26461 tttgctgcta catctattgg aaaatcagca aaagcactct tcgctgtacc ttgtcttaca
    26521 accaatttca taccttttgt taattctttt aagttatctg gatttttaaa aggtattttt
    26581 tcgactttct tctggtcatt aattttaact gatgaataat cacttgaaac agctctatca
    26641 actacagata attctactaa attacctcca tttgctatag cagctacata tcttgatatt
    26701 tgagctggtg tataagcatt ttcaccttga cctatagcta agttaaatgt atctgcagta
    26761 ctccattttg caaagttaaa ataactaaat actgctaaat ctgctacttc ttcaattcta
    26821 tcttctttaa catccaattt ttttagccta ttcattgttt caactctacc aggagttttc
    26881 ttttctgctg cccagcttac aatctcattg attcttttct catattcttt aggatttttt
    26941 tctctagtta tatcaacaaa atcatttgcc atttctcttt ctaaatttga ctttagaaga
    27001 gcttgtgttg atttcaattt atcttctgtg ctaggaactt tacctgctct ttcttctact
    27061 tcatcttgaa gccctgtatt ttggtcaagc ccaaataatt ttgcatactc aagtatttta
    27121 tttgcattca tatctatacc aatgcttttt ccatctggcc atgttttacc tgtaccaatt
    27181 gttgccatat atatattaca agactcttgt attgctttat ataagtttgt cataccatgg
    27241 tttcctctac catggttcca tacatagtca ccaaaagatt ttttacctaa cattataacc
    27301 ccagggtcat ttatagtaaa gtttggatcc agaccatttt ctaacgctgc cattgaagtt
    27361 agcatcttaa atgaagaacc tggctgaaat tccccttgtg taaccaagtt taaaagtgga
    27421 cttcctgcta gtaagtcatt tggatttttt ggttgaagtg ctttataatc ctctgtagaa
    27481 ataccttttg caaatttatt tgggtcataa ttaggataac ttgatgaagc taatacttct
    27541 ccatttttaa catcaatagc tataagagct gctgactgtg cttttcctgc atatgcacta
    27601 attggtttgt ccccaaattt acttttaaaa gtacctcctt tagaagcaac ttcgattatc
    27661 tgttttaatg cattgtctga aacttcttgt aaatctttat ctagtgtaag atacacagta
    27721 tctcctgatt taggtttttt agattcaatt tctttactga ttctacccaa tgcatcaact
    27781 ttaaccattt tataaccatc agttcctctt aatctacttt cattactctt ttctactcct
    27841 gcaagaccta ccatgtctcc agtttcataa cctttttgaa ggtatgattc tatttgagtg
    27901 gatggcattt ttcctacata tcctaacata tgagaagcta atgacccatt aggataatat
    27961 cttactggtt ctactgctat tgaaacacca acaaggtcca tagcactttc ttcaatttga
    28021 gcaatcgtag tttctcctac atccttagca atagttactg gattatattg agaatatcct
    28081 tttgatttta tcaaatccct tacgaccatt atttttcttg catcttcatc actcaaactt
    28141 ttatcaattt ctaatgcatc actatttctt actttttcaa acgcttcttt ggcactcagt
    28201 ttagtttctt ttatcttata actagccaac caatctctct tatctctttc tgctgtgaac
    28261 atccatttac taactaaaat aggtggataa tatccatttt catttagttt tgcctgtaat
    28321 cttgtcgcat ccaatctttt atcttcttga gataatattc cagctgatat aagtttatcc
    28381 accaagtaat aaaaactttc cttagcatta taatcatttg gaataccatt ttctgattta
    28441 tattccctaa tatctctgtc atatgtataa tagtactttc cattttctac atatatagga
    28501 aactcatcta catattcttc accatttctc tccagcaaat ttataagttt taatgatatt
    28561 tcatttgctc ttgaatgctt atttgcatct ttcttattaa tatcgttacc tgaaacttga
    28621 acagtaaata agtttttatt tcctgccaac agtcttccat atctatcttt tatttctcct
    28681 cttggagctt ctattgccaa ctttttatat gttttattct cagctaactc attgtaatat
    28741 tcatatttaa atgtagtcat atagattatt tttactaaaa tagctaaaaa tatcacgccc
    28801 atgactatct taattatttt tagtctatca acttgtttat tttcttccat gaaatcacca
    28861 actaatcttc tttaagtttt aaaactgctc ttttagataa gcgatatatt actaaaccaa
    28921 ttaaactatt cactattggt gctactagta gaccttttac aaaaagtgtt gatatgttgt
    28981 agctttgata aattatacta gatgtaccta tattgacaat tgaatcaatt aaactgccta
    29041 taaaaattaa aacgaaagta ataatataac tacctttata tagctgatct ctcatgtatc
    29101 caattgcata tgcaataata aacaaaatta atgcatttac accaaaaatt ccaccaacgg
    29161 ttatgtcttt aataagccct attattgctg ctataatccc accttctaat tcatctaaat
    29221 aaagagagat tatggttaca tatataagaa ctaaattaaa gcttatgcca aaaatatcta
    29281 tataatttgt tatactattt tctatagtca taagcacaat ccccaacaga caaagtaaaa
    29341 cttttttcat tgtttttatc ccctttatcc tatatttctt ggttctatga ctacaacgtc
    29401 atttatattc ttaaaatcaa cataaggttt tacaactaca tattttaatg acttatcttt
    29461 atcatcaacc actttttcaa cttcgccaat tggtatacca tctgggaaga atccaagacc
    29521 tgatgttgtt attatatctc cttgaattac attatatgat gagtcaaaca tatatccttg
    29581 caaatatcct ttactattat aactatcttt attatctaaa gtagtatttt gagtaattgt
    29641 acctttagca ttggcatcct ttgctagttt aaagcttaca gatgccttag aatccaatag
    29701 tgaaattgcc ttactataat tgttggaaac ctcataaact atgccaacta atccactacc
    29761 attcataact atactttctt tttttacacc tgaatttttt cctgcaccta tgacaaaact
    29821 ctcataccag tttccatcat ttttaccaac aacacttgct gaaatacttg tcgccttata
    29881 ctcttcttgt acaaagttca gtgtcttttt taactcttct agcgattctg ttttatctag
    29941 tttggcattt aaagctatca tatttttttt aagtttttca ttttcttctt ctaatttttt
    30001 taccttttta gaattatctt taaaatttgc tacatcttta aaaccatttt tgataaaaga
    30061 aaatccatca tttattccct tacctacact tgtaatagca tctgaagcta ctcctaaatt
    30121 tactggacta ccactagaaa atttaccaat tgatataccc acaattccaa ttaaagtgat
    30181 agcaactacg cccgttgcta tcactttaac attaatcctt tttttctcat ttttgttctt
    30241 gtcaaatctc aaggccatca ccaacttcta attcttagta ttcatcatta atactttttc
    30301 aaagatttct tggtcttcaa cagatttacc tgttccaagt gcaacacaat caagaggtgt
    30361 ttctgctatt tgtacagaca taccagtttc ctgtgtaata agcttatcaa gacctctaag
    30421 caaagcgcct cctcctgtta gcattattcc gttttccatt atatctgagg ctaattctgg
    30481 tggagttctt tctagtgtag attttattgc atctactatt gaacttacag gttcttttaa
    30541 tgcttctcta acttctgtag agcatatttc tattgtttta ggtaatcctg agattaaatc
    30601 tctacctctt atttgcatat ttatttcttc atcatcttta aatgtagaac ctatgttaat
    30661 ttttacattt tcagcagttc tttcacctat cataagatta tattcttttt ttacataagc
    30721 cactatagac tcgtcaaatt cgtctccacc tattcttata gatttagcag taacgattcc
    30781 tcctaaagat attacagcta tttctgaagt acctccacca atatcaacta ccatattacc
    30841 ttctggttct tcaactttta atccagcccc tatagccgct gccattggct cttctataag
    30901 gaatgcatct ttagctcctg cttgtcttgc agcctcttct atagctctct tttctacttc
    30961 tgtaactcca aaaggaacac atatagctat tcttggactt acaacacctt ttttatcagc
    31021 cgctttttgt ataaaatagc taatcattga ttgagttatg tcaaaatcag ctattactcc
    31081 atctttcata ggtcttatag ctactatatt tcctggtgtt ctacctatca tttttttggc
    31141 ttcttcacct actgctaata cctctttact atcatctctt attgcgacaa ctgatggttc
    31201 tctaacaaca ataccttgtc cttttatgta aactaatgta tttgcagtcc ctaaatctat
    31261 tcccatatcc tttgtcatct tattaaaact aaaaaaacct tttttttctt tctttttttc
    31321 cttagccatg attttactcc ttcctactat taagaatcat gtttaaaaca ttctcctatt
    31381 attttatcac atataaagtc aaattatcat attttcttta aagctaaagt ataatccatc
    31441 tccaataatt atatggtcta ttatttctat tccaattatt tctccacatt taataagtct
    31501 tgatgtgata tttttatctt ctcttgatgg ttctacactt cctgaagggt gattatgcat
    31561 cactattatc ttacttgcac ttcttcttat agcttcttta aaaacctctc ttggatggac
    31621 taatgacgag cttaaagtcc ctatagatac atctacatca gatattatct cattttttgt
    31681 gtttaaaaga accgctttaa aaacctcttt ttttaaatac cttaggctat ccatataata
    31741 cctctgtata tcccaaggat tccttatttt atactttata ggtttaaaac tagctactct
    31801 agagcctagt tctaaagctg ctttaatttg ggttgatttt gataacccaa ttccatctat
    31861 attacacagc tcctctattg tcatatcttc taaatgtcta ataccctgaa tatctctatt
    31921 tattatatag ttggctaatt caatagcatt tttattcttg ttgccagttc ttaaaagtat
    31981 agccaacaac tcagcatttg ataagctttt tacgcctttg gcaagcatct tttctctggg
    32041 tctttcctct ggtgccattt cttttacctt aatggttgaa ttaaatgact ttttcagata
    32101 aatcacactc cataaaaaag atttatacta aaatattttt ttaataggtc gcctaacctt
    32161 gaaattggaa gaccaactat attaaaataa tctcctctaa tttcttcaac taacaaagct
    32221 ccataaccct gtataccata ggctcctgct ttgtcaaatg actcattagt tttcagataa
    32281 tcctcaatat cctgctctga taacgtttta aatttcacat tgctgattac atagtcaatt
    32341 acctttttat cttcgcacaa gtttattaag ctaatacctg ttatgacttg atgctctctt
    32401 ccagatagtc tttttaacat atctcttgca caagactcat cttttggttt tcctaaaata
    32461 gcattgtcta aaacaacaac tgtatcagct ccaataacaa catcttcatt atgttcagat
    32521 gctacagaca tacttttttc aaaagctaat ctcataacta aatgttttgg tgtttcacct
    32581 tccaatataa tctcatcaat ttcattttta attatatcaa atcttacatt cgtattctct
    32641 agaatttctt tccttcttgg agaggctgat gccaagatta tattcattta ttcacctcat
    32701 ttgtacgtaa tttgtaccta tttagtctat cactatattg taaaaaattc aacagaaatg
    32761 tcgaaccttt tttgttacac tattgttata tttattacca ttagaataaa tatacataaa
    32821 atagaggtat ggaaattatt ccatatcctt attttgtcca tattacaaaa ttttaatagc
    32881 tttctttgga catttttcca tacataaatg gcatcctaca catttatctg catctacctt
    32941 atgtttttct tttaattctc cctctattgc atcaaactta cattgttttt tgcacactgt
    33001 acatccaaca caaagttctt ggtcaatagt aactttcttt ttcttagtta tgtcacctga
    33061 tattactttt gtagggcatt ttgctacaca ttgcatacaa cctacacact tattagggtc
    33121 tatcttagct attttgtctt caaatattat tgcatcaaat ttacaagctt ttacacacat
    33181 tccacagcca atacatccag cagtacattt ttctttaaca gctttaccaa actctttgct
    33241 attacactct acaactactt cttgactttc tggttttgtg attattatac ccttaggaca
    33301 aacttcttta cattttccac aatttacaca cttttcttca tctattactg ctattccatc
    33361 aactatagaa atagcatcaa atttacaagc atctttacat gttccaagac ctaaacatcc
    33421 aaatttacac atcttagcac ctgagtttaa aacatttgct gctctacaat ctgatattcc
    33481 ttcatactca tatttatctt ttgcacttga acaagttcct ttacaaataa cttttgctac
    33541 ttgtttctca cctgcttcag cacttattcc cattatttct ccaacttttg caccaacatc
    33601 tgctccacct acagggcaac cattaactgg tgcattgcct tcaactatcg catttgcaag
    33661 acctccacaa cctggaaatc cacaacctcc acagttggct cctggaagta ctcctagtat
    33721 agcttccact ctctcgtcta cttctacagc aaacttttta gatgcaaaat ctagtactat
    33781 cccgaagatt aagcccataa ttcctaaaac taatacagct gtaagtatca ccattttcac
    33841 ccctcttttt tatagcttta taagtcctgt aaatcctaag aaagctattg acattaaacc
    33901 tgctgatata agcgttatag ggaaaccttt aaatgcttct ggtatatcag ctaattctag
    33961 tctttctctt atacctgcga atattactat tgctaaagta aatccagctc cggctccaaa
    34021 tccgtttatt attgtttcta ctaaattata acttttttga acattaacta gagctatacc
    34081 aagaactgca cagtttgtag ttataagagg taaataaact cctaatgctt gatataaaga
    34141 tggactcatc ttttgaatta ccatttcaac gaactgaact atagaagcta taaccaatat
    34201 aaaagctatt gtttgtaaga atccagttcc agtttttact aataaaatct gtataaaata
    34261 agttataatt gaagctagag ttaaaacgaa tgtaactgca actcccatcc ctactgctgt
    34321 atcaaccttc ttagaaactc ccaagaaagg acatataccc aagaattgag atgttataac
    34381 gttattaaca agaacgatac ttaaaaataa aagtattaaa ttcatttatt acacctccac
    34441 tatgcttttt tacttcttaa tttattaaat cctgcaaata agaatcctaa tgttaagaat
    34501 gcacctggtg gtaatataaa tattaatact ggttggaaag atgctccaaa taatgtcatt
    34561 ccaaataaac taccatttcc aagtaattct cttactgcac ctattattgt aagtgcaaca
    34621 gtaaatccaa gaccttgacc tacaccatca actattgaag gcatagctcc tgttttgaaa
    34681 gcaaaacttt ctgcacgagc taatattaaa cagttaacaa ctattaatgg tatatatata
    34741 ccaagagcct tatcaagagc aggaacatat gcttttaaaa gcatacctac tattgtaaca
    34801 aatgtagcta taactactat aaatataggt attcttatct tatctggtgt aatttttctt
    34861 attaaagata taactaaatt tgcacatatt aaaactgctg ctgttgaaag acccatacca
    34921 attccattta ttgctgaagt tgtaacggct agtgttggac acatacctat aacttgaaca
    34981 aatgttgggt tctcatctat tagcccattt ttaaatactt tagctaaatt cataattaac
    35041 cctccttatt tattaagagc actattgaaa acatctatag cagcatttac tcctgtagta
    35101 actgctgtag atgtaatagt tgcacctgat attgctaata tttgattatc tgctgttgta
    35161 cttccttttg ctacttcaag aggctcagca gtttttcctt tgtattgacc cttaaatgca
    35221 tcatccttag cttttgctcc aagacctgct gtttctgaca tattaccaat gtcaacacct
    35281 gtaacttgac cttcagatga tatacctacc ataacttcaa tttctccacc atatccactt
    35341 ggtttagctt ttaaagtata tccaaccact tcagaaccat ctaaaccttc atacacttca
    35401 gctataagac catctccaag gcctttgtaa gtatcttcct tcatttcttt aaattctttt
    35461 gcttctggaa ggactgcttt tctaagttca ttatttgctt gtatatttct ttgttctatt
    35521 actggagctg taacctgatt agtagctcca agagctaatg cagctattgc acttatagca
    35581 agtaaagtac cacctaatct caccatactg ttcattattt agccacctcc ccaaatactc
    35641 tatttctaac aaacttatct ataagtggag caagacagtt cactaatagt attgagtaag
    35701 atacaccttc tggatatcca ccatacattc ttataacagt tgttataaga ccagctaata
    35761 cagcgtatat tatttgacct tttttagtca taggcgaagt tgtataatcc gtaagcatga
    35821 agaatccacc taacataagt cctccagcaa acagttgata tattgcgaaa gttatattaa
    35881 atccacctaa aaggaatgtt aatataaata cagttgctat gtaaaatact ggtataacat
    35941 aatttattat gcctttatac attaggtata ctccacctaa taataataat attgctgatg
    36001 tctcacctat acatccacca atattcccta tcatcatgtc agcaagacta attccattgc
    36061 tagaaaggtc tgccagtcct gctgctccat ttttcaaaaa gcttaatgga gttgctgtag
    36121 taactgcatc taaattttta cctatccagt taacacctgg ttgagtccaa gcagtcattg
    36181 ctactgggaa tgatgctaat aaaaatgctc ttgcagcaag tgctggattg acaaagttac
    36241 atccaattcc accaaatacc attttaacta ctaatattgc aaatattcct cctactagac
    36301 acatccacca aggaagtgat gctggtacgt taaatgctaa taataatcct gttacaacag
    36361 ctgaaaaatc tcctatagta cttttttgct tcgtaaattt ttgatataaa aattcagtac
    36421 ctactgtacc aagtatacaa aaaaacatag cactcaaagc attaagtcta aagaagtata
    36481 ctcctgctac tgctgctgga aggagtgcta taataacttg tttcattata tatgaagtat
    36541 cttcattact tctcacatga ggagaagatg atactatcaa cttattttcc atcgtttttc
    36601 ccccttaact ttctttattt ctgagcagct tgctttcttc tctttgctcc tatttctctc
    36661 tttgctgatc ttatagattg aagtaatggt cttcttgctg gacaaataaa tgagcaagac
    36721 ccacattcta tacaatccat tgctctatga tattcagctg tgtcatagtc atcttttaaa
    36781 gaatatgcac ttatgaaaag tggttgtaag aatgatggac atacatctgt acatcttcca
    36841 catcttaaac agttttgaat atctggagta cgtgattctt cctcatccaa acataaaatt
    36901 cctgaagaac ctttgttagt cgctatttca gtagtatatt gagctattcc catcataggt
    36961 ccacccatta taaccttacc aatcttctta tcttctttaa atccaccaca ttgttctatt
    37021 atttctgaaa ctaatgttcc aacttttgtt attaggttct ttggctcttt gatgcaacta
    37081 cctgttattg tagtgattct ttcaaccaaa ggcatacctg ttttaataga cttagctatc
    37141 tgtgctgctg tggcaacgtt gtcaacaact gcacctgctg ctattggtaa tccaccagat
    37201 ggaacttctt tgcctgtaca cgcataaata agttgtttct ctgctccttg tggatatttc
    37261 acttgaaggc caacaacttc gatttcgcta tagtctttag ctacattttg aattgcttct
    37321 atagcatctg gtttattcgt ttcaattcct ataaatcctt ttttgacatc taataccttc
    37381 attaatgctc ttaaaccaaa cacaacatct tctggatttt caaccattaa tctgtggtct
    37441 gcagttaagt atggttcaca ttctgcacca tttaatataa ctacttctgc cttgctatct
    37501 ggtggaggag atacttttac atggttaggg aatgtagctc cacccatacc tactattcct
    37561 gcctctttta tgatacctac tatatcttct ttgctcaaat cctctaactg accttttggt
    37621 tgaacactct catgtaattc ttccttaaag tcattttcga taactacaca ttgagctgaa
    37681 cctcctggta cttcatgttg ttcaatagca ataactttac ctgatactga agaatgaacg
    37741 ttacatgaaa caaaaccttg ttgttcacct attttttgcc caaactttac ttcatcacca
    37801 acttcaacaa taggtttagc tggtgcccct atatgttgct gaagaggaat gtaaactatc
    37861 tttggagctt gagctttttc aagtgccttt gtgttagagt actcttttct atatggagga
    37921 tgtatccctc ccttaaaagt taagagtttc attgttttac ccccttatct ataaaaaaac
    37981 attttttctg ccttctataa gtatactata tatattaaaa aatcttaaca attgttaaaa
    38041 aaatatccgt atttttataa tttattttat aaatcaatac ctctatatta agtcaaaccg
    38101 aggaaaagga ttgcttaatt aaacaatcct tttcatatag ctttctaaag tccaaatttt
    38161 ctgtatttta ttttatagaa tttataaaca tagagtactc ctgcatggat gataaaagca
    38221 gacttttact tacactatat ttttcttcat ttgctgcttt tgaagctgta tcaatttttt
    38281 cattcacatt ctttacatac tctattaaat tatctttaaa taaacgcatt tcagaatagt
    38341 caatcttttc agcttctttt gatatatttt gtgatattgc ctttctattt gtcaaaatag
    38401 tattatattt ttccatatct acattatttt cagcattcga ccaaaaactt gattcttctt
    38461 taaagtttgt tattaattta tttaattctt tagatatact ctctatataa gcgtagttac
    38521 ttgtatactc taaagacaac ataggtgcat ctaagtgtga taaaaatgca tctggaaaca
    38581 cctttcttac actgcttatc tgctttctaa catcattttc atcaaaagag gaataggtct
    38641 gtattttttt tactccatcc ttctccataa ctgaaaaagg tatgtcatta ttaactaatg
    38701 atgtctgtat ttttttcaaa tcatcattat tatctattgc agcaacttga atagtataca
    38761 tatcccagcc ttctatagta gctaatttga cttcttctgg ctctttagtg ttatttaccg
    38821 ctttttctgg attagtttct tgtttatcat ctgaattggt ttgtgattta gattttttcc
    38881 ctttttttat tgaatttaat tcatcagata tatctttata agttatatct gatgaattat
    38941 ttagaaatgg tattttagcc gatacatact ccaatatctt gctatctttt atttttgtat
    39001 aagaataata gccaattaga cacaagcaag caatcgttat aacatattta cgtaaatcaa
    39061 tcttatgtct attattatta aatcctctgt atatcgtttt tcttctattc attagtttgt
    39121 ccctcccaaa attatattat taataaagta tatttttaag agtcacaatt tatgaatata
    39181 aataattatt tcttctaatt ttttaataag aaattgtact tactaaacaa atcttcttgc
    39241 accaagtaat actttagacc aatatgaact agttaaatta tctactttaa ccttattagg
    39301 attagtctga gtaccactac aatggataaa tttactattt cctacatata tacctacatg
    39361 attagttgtt ccatcaccat cagtgtcaaa ataaactaaa tctcctggtg cataattccc
    39421 catagaaatt gcacttccaa aattagcctg ttctctagaa actctaggaa tagaaacgcc
    39481 tacagaatgt ttaaaaacat actgtgtaaa tccagaacag tcaaatttat caggccctga
    39541 agctccccat tgatatggta ttccaataag agtatatgca aaatctacga ttgttgaacc
    39601 ttttgctgta gatttatctg aatttccagt aaatgatggc tttgagttac tattagattg
    39661 agaattttgg ttagatgatg aatttggttt ttcttttgta tcctcattag tctcagaaat
    39721 ataactggca ctcacccatc caattgttcc actcgataac tttaccttat accaaccatt
    39781 acttttagct tttaattcaa caacatctcc accatttaat tttcctatta tagaatagct
    39841 tgtcccagga ccacttctta catttaaact cacagcagat gttaccttac cattctttcc
    39901 ttcaattgat tcttcgctag atggtttttt atcagaatta ttagtactat ttgaattact
    39961 agaattgttc gttccaacat cctctgatgt tttagagata tattggctac tagcccatcc
    40021 agtaactcca tttgatagtt ttattttata ccatccattg ctttgttcta gtaactttac
    40081 tacatctcca ttatttgctt taccaactaa tgaatagtta gtacctgcac cacttcttac
    40141 attcagtcta gaactcacat ttactttacc atttccacta atagttgtcc cacttgaagt
    40201 tgaattattt tgacttgatg taccttcaga cgaaccactt gttgatatgt attttgcact
    40261 tccccatcca acaacagaac tcgataccct tactttatac catccattag acttttctaa
    40321 aatctctaca gtttttccct tgtataattt tgctacctta tcgcaatcag aacttggtcc
    40381 acttcttata ttcaaggcac ttgctgttac tgttcccttt tcaagagcac ttgcatttat
    40441 ggagctaaca gatactgcta ctgccccaat tcctaaagct gctatagctt ttttcactac
    40501 tatcactccc cccaacaaat ttttatagtc ataaattcat aacattatta tccattttta
    40561 gtccctacaa tttaatgata acttattttc ttattaattg taaagaaatt ataaacatat
    40621 ccttaaaatt agtgattttt aggaagtatt tcaatccaat aattatctgg gtccgctata
    40681 aaataaattc ccatactttc attttcaaaa catatgcaat ctaaatcttt atgaagtttt
    40741 tttgcctcat caaactcctc aacttctaaa gccagatgaa attcattgtc tcctaaatta
    40801 tatggtctat cccaatctct aagccaagtt aattctaatg tatgactagt aatgccatct
    40861 cctaaataaa ctaatataaa acttccatct tctgcttcct tgcgctttac ctctttaagc
    40921 cctaaagctt ttttataaaa atctaaactt ttttctaaat tagtaacatt gaaattgtta
    40981 tgacaaaaat taaacttcat tttgaaatca ctctccaatt tttatttttt ttatattata
    41041 tcattattat aaatttattt aaatcatatt aagttaaaaa tttgaatgat gatgaccaat
    41101 taccaaatca tggtaaatta tttaaaagaa tatgtcaaaa aaagaataag ctctttcaaa
    41161 tgcataaaaa atttataccc aagttatact taatcatgca aattggcaga acttattctt
    41221 taaaactcta acttttaagt ttttctttaa taatataatt tattactttt tttctaatat
    41281 cttcagcatt ataatcatct tctacttcta tatccaaaag ttttgctatt gacctcatat
    41341 cttctctagt ctttgaccta tagcttgata ttaattcatc ttttattttc tctggttcta
    41401 aaagatattc ttcatctcct cttttgaaaa caacgtattt ttgagcatat gaacttctat
    41461 tgtagtatat atatcttgat atttttctta aaatttgatt atatgaaagt cgcttgttaa
    41521 tatcaagttt taagtactct gaaaaagcaa atagctcttt ttttgattta aataatgctt
    41581 ctttctttat agtccttgat attgaagtta cactttcttg atatgcacac ttttttaaca
    41641 tttttaaata tactctatta agaccaatac tttgattgaa tttttttata ttattattaa
    41701 taatcttatc caagttacct tcaaagtatt tttttgctcc tttttgtgat acataactct
    41761 caagttcttt gtgggccata tcaagtatca ttttttttaa atcctcttta tatcccctag
    41821 attccatgat actccctccc ttagctattt atagtatatt caaaaagctc aagaaatgtg
    41881 agtcattaca aaattttttt actttttatg tatatattaa tttaaaaggg gagataatag
    41941 taatgtaaaa tcaaacatac tcaatctccc ccatttttag acctctatta ctcccccaat
    42001 agaggtcttt ttttagttta tcaatttcta ttcaattccc tttagttcaa atcctaattc
    42061 tgctatcact tcttttaatt tttcaataga tacatcatct ttcatatcta cagatgcaca
    42121 cttattttct aaatctacat ctaaaacttc aataccatct atatcttctg ttaatgcagt
    42181 tttaagatgg tttacacaat gaccacaact cataccttct actaatagtt tcttcttcat
    42241 ttaattacct ccttataccc tataagggta ttctatcata tagtttatac tttttaaata
    42301 gaaattaatc atttaatttg attcattcga ttttatatct aaattagata ttccctcata
    42361 tacatcaaaa tcatttggag taattttacc ttttaatcta ctattactta caatatagtt
    42421 gtttctcaca gctaaactta taaatgttgc attatctttt atatatgtct gtacatcttt
    42481 gtatgctttt tttgtttcaa tttcagacgt agaacttgta agtgcagaca tatatccatt
    42541 taacttatca tcagtatatc cactactcgc tataatacta cttgcatctg gtataattga
    42601 tagtttccat ccaactaatg ctaaatcata atttttagaa ttaagagcat tttccatatc
    42661 cttatctgac agctgattta ctgtactatt tattcctata gcttttaagt tttcatttat
    42721 tatgtttgca gtttttattc tctcactatt atctctgttt actattatct ttaagttcat
    42781 ttcagaaaga cttttcttta cttcctcttt ttctctattt tttttctctt cagcttcttt
    42841 tttgattcta tcttcttctg cttttttagc ttttgcttct tcttctggcg taagcttctt
    42901 tgagttcttt ttagctgatt ttttctgatt ttttacttta ttgtcatttt gatttactga
    42961 gtttacattt gcatattcta ccttagcaag acactctatc gccttatctt tattaaactc
    43021 taaatccttc atttcactat tatagtattt tgattttgaa ttaagtggaa aattaactgg
    43081 agtagcatca tccatataac cttcactaat aattctatct ttatctatag agtgtgcaat
    43141 tgcttttcta aaattaacat ctttgaaaaa aggattatta taattaaata atacacactc
    43201 ataatctctt ccttgatatt ttgttatatt aaactctttt tcttgaaact tacttaaatc
    43261 atttaatgta acattggtta tatcactatc aagagccata accatagatg tccttgcatc
    43321 ttcattaggc accataccta cttttatgtt cttcatggtt tttggaactt cttcatagta
    43381 atctttgttt acagataaaa ccattccttc tctttctgta tatgattcta ttttatattt
    43441 cccatttcct atcatattat tattcttgtc atttacatct tttgaatcta aatgattttg
    43501 agatacaatt ggaaaaatta aactatcaat tgaaaaagca tatctagctt taaattttat
    43561 tgtaaagtct ttatctgatt taatattcac agaagctata tttttagtaa attcattata
    43621 tggactatct gcactttttt gaattaaacc aatagtatag tttacatcat ttgaagtaac
    43681 attttttcca tcatgccact ttgcatcttt tagctttata tctatactca ttccatcctg
    43741 agctatatta tactccttaa ctaattgagg aattacattg tagttctcat ctatagtaaa
    43801 taaactatca taaactaaat tcattatata accaacagac ttatcagtat tagttatagg
    43861 atttatagtt tttggagtta ccattgttaa gtttatatac ttagcatcta tagaactttg
    43921 actttgtaaa cttgaatcac tactactttg ttttgtttta gtattactac aaccagctac
    43981 cataagagtt atagctaaaa cgactgttaa gacttttatt ctcttcatta gttttttcct
    44041 ttcttgccat atatcttatt ataatgttcg taattatttt ttactttttc tacatatttt
    44101 gaagtttgct taaaaggtat atcatgtaga ttttcgccat ctttactata ttcattattt
    44161 tctaaccatt ttttcacatt acctgaacca ccattatatg cagctatcac taaatctaat
    44221 ttaccaaatt ctttgtataa cttacttaaa taccaacagc caagtcttat attagtctct
    44281 gggtcgaaaa tatccacatt ttttaaattt agttcctctg ctccccaatc tctagttatg
    44341 tctaatattt gcattaatcc ttttgcttcc ttttttgaaa cagcagaact attaaactta
    44401 ctttcggctt taataacact gtaaactata ttttcatcta aattaaattc tttcgaatac
    44461 ttttctacat actctgaata ttttttagga tataaaaatt tatgtattac tttgctttcc
    44521 attaatagtg ccccaaataa gattataaaa atagatagaa tcaatacttt cttactattc
    44581 acgccaattc tccttcatgt actcaataaa tttatgtgct ttactttcta attcagttat
    44641 tgttcccgaa ttatctatta tataatcacc atatttggat ttttcttcct gactcatctg
    44701 tgaatttatc ctactaagtg cttcctgctc actgcaatta tctctctttt gtattctact
    44761 aatttgtact tcttgtttac aagtaactac taatagcttg tcaaccatat ctaaaaaacc
    44821 actttctacc aatattgccg catctaacac tactatattt tcgccttttt ttctcaattt
    44881 ttctatttca cttattattt tttctcttat tcgtggatga gtcaagttat ttaattcctt
    44941 aagtttttct tcatcactaa aaactatttt cccaagagct tttctattta gagttccatc
    45001 atcatttttt atactttgcc caaaatggac aaatattttt tccaataaca acttatcctc
    45061 aaatatcttc ctggatataa tatcagcatc cactatagga atgttaagat ttctaaatat
    45121 atttgatagg ctgctttttc cacagcctat tcctcctgta agtcctaata tcaacataaa
    45181 atcacctact ttgtctcata ccaagaacta cctacattta aatctacatc taagtgaaca
    45241 tccatattta cagcattttc catttcttct tttactattt tcttaactat atctatttca
    45301 tcatcaattg cttcaactat caactcgtcg tgaacttgta gtataagttt tgatttcaaa
    45361 ttgttctctt ccaatttttt atgaacattt atcatagcaa tttttattat atctgctgca
    45421 cttccttgta ttggtgcatt cattgcaaat ctctttcctc tatttctttc cataaaattg
    45481 cttgacttta tttctggtat atatcttctt ctgtttaaaa ttgttacagc atatccatcc
    45541 tcactagcct tttctactgt tgtgtccata aactctttta ttttatggta tttagcaaaa
    45601 taactttcga tatattcttt cgcctttgga acaggtatat ttaaatcatc agctagacca
    45661 aagtcacttt taccatatat aataccaaag tttacagctt tagctgcacc tctcaattca
    45721 ctagtaacat cttccatagg aacattaaaa acttgtgaag ctgttttggt atgaatatct
    45781 tcatgatgtt taaatgcttc tatcatattt tcatcctgac tcatatgtgc aagaactctt
    45841 agctctactt gtgagtaatc ggcatcaacc aacttacagt tatcatctgc aataaacact
    45901 tttcttattt ttctacccat ttccattttt ataggtatat tttgaagatt tggttctgta
    45961 gatgaaattc ttcctgtagt cgttatagtt tgattaaatg atgaatgtat tctattactt
    46021 tctggattta ttatatttaa aagtccttca acgtaagtag aatttaactt tactatttgt
    46081 ctatactcag ttatcttatc tattattgga tgcttatctc ttaatttttc taaaacatct
    46141 gcattagttg aatatccagt tttagttttt ttaattattg gaagctctaa tttttcaaat
    46201 aatataacac ccaattgttt tggtgaattt atattgaatg gctctcctga taattcataa
    46261 atttcctttt ctaatgtagc tattatttct ttaaattcaa cactcaattc atccaatata
    46321 cttttgtcta cttttatacc ttcatactcc atatgaccta agacttctac taaaggcatc
    46381 tctacatgat aaaaaagacc atccatactc atatccatta gacttctttc catcatagga
    46441 actgtttctt taactgtgca tattatttga cccatatact ctgctaaatc ctcaaattct
    46501 aaatcctcat agtttttaga tttaacaccc tttcctaata attcttcttt tgatttaacc
    46561 ttttttgata aatacttcat agctattgca ctacaatcat atgaggtaga tgaagttgaa
    46621 tctattaagt actcagctat tgttatatca aaatacatat tttctaagtt tatattatat
    46681 ggttttaaag atatataatc atcttttaaa ttatatccat actttttaat ttcattattt
    46741 gaaaatatac tatctaactt tgacacttca tttgaatcta cataatatat tttttctcca
    46801 tctacactta taaaaatata tattatattt ttttcaagta tattaccttg tcctctaaca
    46861 gtttttaaaa taacttgtcc ttttttgttt acttcatcta taaatttttc tatatctttt
    46921 aattttaata tttctatttt ttcttctacg tgttctgtgt catctgaatc gaccaaatca
    46981 actaatcttg ataagagact tgtaaatcca aagtatctaa atttatctaa aagttcatct
    47041 ttatcataat cgccaaaaat catactatct aaatccactt ctattggcac atctcttata
    47101 attgttgcaa gtcttttact ttgaatagct atttctttgt tttcctctat tttctttttt
    47161 acactacctt taagcttatc tgtattctct attagattct ctatactaga aaactctttt
    47221 ataagcttta tacctgtttt ttcacctatt ccaggtactc caggtatatt atcagacttg
    47281 tctcccataa gaccctttaa atcgataaat tgtgttggag tcatctcgta tttttcaatt
    47341 acagaattaa agttgtattc ttcaacttct ccaactcctt tttttgttat aagagtagtt
    47401 gtattgtctg aagcaagttg aatagcatct ttgtctccag ttactatgta taccttatat
    47461 ccattttctt ctgctttttt agaaacagta cctataatat catctgcctc atagccatct
    47521 atttccaatc tatttattct aaatttatct aaaaggtctt ttaatggctg taattgttct
    47581 gccagttcat ctggcattcc ctttcttcca gccttatact ctttatattc taaatgtcta
    47641 aatgtaggtg cttttctgtc aaatgctaca cttatatgtg ttggtttata tatatctatc
    47701 attttaaata gcattgttgt aaatccatat attgcattgg tctttagccc ttctttatta
    47761 ttcatttctg gaagagcata aaaagctcta tttattattg aatttccatc tattataatt
    47821 aatttttttt ccaaattata tcactcctaa aaattatcta tttttgtaac atatatatta
    47881 tataccaata tactgttatt taatattccc ataataataa tagtatatta aaattaaata
    47941 tgttgcaaac aatatatttt tttgctataa taatatacat gacatgcccg agtggtggaa
    48001 ttggtagacg cagtggactc aaaatccacc ggactaatac tccgtgccgg ttcgagtccg
    48061 gcctcgggca ccattaaaaa ctcctaaagc tatttattca atagattagg agttttttta
    48121 tttttgattt aaattttaag ttattttttg aaattactgt gtctttttaa aatttatata
    48181 attatataaa tttatcttct agcattaatt taaaaactaa tttactttta tataattttc
    48241 tattttatat cataacttat tacaaccttt tatctaattt attgtataca acaacactac
    48301 aaataaattg aaataaaata agcaatccaa gaacaactaa aacccacttg cttattacca
    48361 ttacagaaaa tacactcaat atagaaacaa taaatataag aattacaaga acatagcaca
    48421 tgatttgatt agtgatacgt ccagctttat cacgtaacat aattcttctt tcatcattca
    48481 tctctatcct ttgatttttt atcttttctt cataatctac tgctctttca ggtttactcc
    48541 aatacatata ttgaagaatc atacatacac ctggacctaa agcagctcca gataatcccc
    48601 aaataaaggc ctcaaatgaa aactcagtaa atgtagccaa taaaacaagt aaaattccac
    48661 aaataaaata tataattcca acatataaca tattcttttt catttttact cctcctcata
    48721 aataaatatt tcttcaatac tcatatcaaa gtatctagct atcttaaagg ctaagatgat
    48781 agaaggatta tacctaccat tttctaatga acctatagtt tgtcttgata cttgcaaaat
    48841 agaagcaagt tcttcttgtt ttatgcctct ttcttttctt atttcttcta atctattttt
    48901 cacatctatc cccctttaat atctcaacta cggaaagtct actttccata attatacaac
    48961 tatattccat ttatgtaaag cttactttcc atatttacaa aaaaataaca gactattttc
    49021 agcctgtaat tttagaattt catgttgttt attaatttta atgttattta ttaattccat
    49081 attatttatt aattttaatt tggtttctga attggaatcc aaacttctgt agtataatca
    49141 ggagcattga tatcgccatt gggataaagt tcaatatctg gtaaattagc atacacatac
    49201 ccagaacttg gtaaccactc agtaataatt cttttttgca attcctgtat tgccagagca
    49261 tttggcattg gagaaacaca ttcaaatact gcccatgtgc ctgatggtat taagtattca
    49321 tgagtatctt ctaatacagg cttatctgtt ggagcagcaa tataataatc taaaccctta
    49381 ctatttgtac acacactaac tccaagcaat ccacaaggtt cgttatttat taactctgaa
    49441 agtttatcaa ttgttccatt ttttatgcat ttagcccata acttaggaac tttctcaaaa
    49501 cactcttcta caatcatgtt catactttct tttataccaa caatacgaaa ccctttcttt
    49561 tctacaatac gatattgcat ttctatattt ccttttacat aaatgcttaa tgtcatctta
    49621 ggatatgctt ttaaaacaac accctttgct ctagctgcag atggagaaat gttatgtata
    49681 ttttgaaaag ctctattaaa agatgttggt gaatcgtaac catacttctc agatagttct
    49741 aaaattttga tgttactgtt ctgaagttca aatgcagcct tagtcatacg tcttcgtcta
    49801 atatattcag ataatggtac ttctgcaata tatgaaaaca ttctttgaaa atgaaaggtt
    49861 gaacaacatg caatttttgc tgcttctgca taatccactc cactttcgag attttcttca
    49921 atataagtaa tagcttgatt taatttattt atccattcca tttgatatta cctccaagca
    49981 aattatacag tttaataaaa taatatacct ctctattcat gcacaaaatt gtaagcattt
    50041 aaattcataa gtatttttca atcaatacaa taaatataaa aattgtatta tacaataaaa
    50101 aagttcaata acattatatt ataaaatgtt attgaacttt ttataaaaat taatttaagt
    50161 gtagttaaat taagtattac actatcttat atattacaat atcctactat cttatagtct
    50221 tctggcactt tataatcttt gtctggagta cctaaattcc attttaaatc aaacatagtt
    50281 gcacttatta ttgttgcaaa ataaagcata actataccaa tgtctatttt ttcttcatat
    50341 aaattagtat gaccatcttt tctaacagct aaaactacag tgcctccatc aactataaat
    50401 ctccatggtt gtctatttaa tgtagatgga gctaatcttg catagtgaaa tgcatcaaga
    50461 agtgctcttt cttctaagat ttctatactt gcaacatttc cccattcgtt catataaaca
    50521 acatcttcta cacctagtct agtagacccc ttatctgtta caacttgcat atcagatttt
    50581 gaataatttt gcccagtttt tgtagcattt aatactttag cattacttac attttctcca
    50641 tatccaatag ctataattcc tgttacctct ttatctgaat taattccaag tttttctttt
    50701 accttttttc catcttcaaa agtaacccaa caagaaccaa ttccaagttc tgttacttta
    50761 aagattatac tttctcctat gtaccctgaa ttttcaatgt aattatcttt tatgtcagat
    50821 aatattataa tataacttgg agaatctatc atatttcctt tgtaccctgc tactttatct
    50881 aaattattaa aaacttcact tctattcata attcttacat caacatctat ttctggaact
    50941 agtttcttac aagattctga gtatttctta atttcactaa gatattcttc tttaatatct
    51001 gtgttcttat attctctaac agactttcta tttaatatga ttgttttata atccataatt
    51061 ttatcctccc caaactagta ttgtcttaat tatataccca ttaatatatt attttactca
    51121 tttatttaat aaataaagat tacaattttg taattattat ttattaataa tattccactt
    51181 ttacattaat aatgaccagt tgtgcaaaat ccattgccaa ccaccaaata aaaacatatt
    51241 ataaaggtaa tataaaataa caaacaaatc ttaacaaaaa attaaacttt ttttacacga
    51301 aagaaggctt cccgttgcct tctttatttt tataaaaaaa taagctgttt ctaaaatgat
    51361 ttcacatttt tgaaacagcc aagttattct ataatgacaa ctataatttg aggatgtgag
    51421 ggagagttgt cattataaat ttagggtaat tatattatgt tttaagctag ttctttctat
    51481 atttatataa tacattttat atatgaattt tatatgagat tggtataaat gatatatgaa
    51541 attacatatg tttatattat attaaatttt attattacat tttccacaac aatactcata
    51601 tgtctccaca ttatttggaa tatttacaaa tacaaattct ttacagttct cacaatactt
    51661 taatatagat atagttccac aagtgtaaca ttcaaatatt acacaatcct cattttcctc
    51721 tactatttca aactttttac tatgttcacc acactctggg cacttgtgat tatttacatt
    51781 cataaatact cctccttatt agtatagtta catgtcaaaa acttaattaa tgtattctat
    51841 attacttatt atatattcta taataaatca tattctaata taataaaaca aattaaataa
    51901 aaaaaaacca taaattttaa atttatggat taattcttgt aatgataact ctatttgagg
    51961 atgtgaggga gggttatcat tacaataggg tattatatta tggtttttaa gctagtcttt
    52021 ctacacctca tatgatacat atgctatatg aattttatat gatttttaca taaatatttt
    52081 atgaaattta aattttttag tcattttgaa atttgtaaaa agttctctaa aaatccacag
    52141 catcataaac agccaaaatt taagtaaaac atcataaaaa aatttgtcca ataattttaa
    52201 caagtaatct cacctcatta taattattga cacaaactta aataaacaat ctataaatct
    52261 tctataaatc ttaaactttc cccctattga tacacaattt ctagtttgtc aattttattt
    52321 tgcatttcta agaaaatttc ttcaacagaa ttgttaaata tattgcctaa atagattctt
    52381 ttatcttttt gaaatgaata agattttaca ctaccatcag aagaaatata taaatgactc
    52441 cactctgctc catattttga aaacctctcc tttgtatctt taaacctcat atcttctatt
    52501 tttattgctt tttctctgtc tcctcttact acagtgtgac ccctttttat taaactggtt
    52561 atttttatat cttcttttaa tttaatacgt gtatcatcat tttttgaata tactttccat
    52621 atcactttat gacgataatt atctaattcc tttattaagc ttctatcaat agtaaaacta
    52681 tctttagtta ccacaattaa atcaaaatgg tctaacatat attgaaatat ttctctcata
    52741 cttttatttt ttaaaatatc ctcaccaata acctctataa atctacagcc tttctcatac
    52801 atgcagttca ataaacttgt gatttcagaa aaataatcat ttgtattatt atctccatct
    52861 atttctatag taaagtacaa aggagtaatg tatgatttat ttcctgttat ctcaaataca
    52921 cttgatagtg tctgtatatc atcttcaaac gttaagtata cattctcata aaacataaaa
    52981 aattccataa ctttttcttt catattatgg atatttctat atctattgga taatatattt
    53041 attatatcgt cagtagtatt tttcccatca cattcagcca gtataacaat ttgcttccaa
    53101 cttaagctat ccacatttcc gatacttttt ttatatccat cttcttcatc ataaataggg
    53161 ccaattataa tgttttcttt tggccacaga tgaaccctag ttccatcttt taatttcgga
    53221 tatttatttt ttacagactc ataaaatcta cttgtatcac ccatgattct ttactacccc
    53281 ccatagttta aatattctat gctaaaaata gcactttatt tttattaatt caacaattat
    53341 tcaaaattgg tcattatata tgtttaaatg gatttaacat caaccttatt tatatgttat
    53401 tgatgtttat atatgttata taaaatctta tttctcatac ttcaatgtaa tcttaactat
    53461 ctctggttta caattaagcc taattaaaac ttttgagcct cctaagcctt tatttaaaat
    53521 catagtgcta ttatcttttt catattttcc ccagtcatac ttaggaaaga actctctatt
    53581 tggagataat acacctccaa caaaaggtat tcttattata cctccatgaa catgtcctgc
    53641 taaaaccaaa tctgctcccc attttgcata tttttcaaag aaaaatggtg tatgtgctaa
    53701 aagaatgtta tattcatttt cattaacttt acctagattg tcttctacaa aattgtcact
    53761 tagttctaat tttttgttat tagcaaataa atatggatag cattccaatg gtataattaa
    53821 accatataaa ttaagatggc tattacctct atatattctt acagattcat tttccatatt
    53881 tattattttc tttgaatata gttccttaaa ataatcctta tatagatgtt tatacttttt
    53941 tattaaagat ttttgttcat gatttccaat tatatgatat acttcatatt tttcaaccaa
    54001 attatctatt aaatctaatg caacttgaaa atttttattt tctccatcta ctaaatctcc
    54061 tgttataaat ataacatctg ggtttaatga ttcaatttta tctatcaata ccttattatt
    54121 tttatcaaac accttattat gtaaatcact cacttgaact attttaaagt tatcaaattc
    54181 ctttggaatt tttttgttga aaatagtata ttctgtcgtt tctatatgct gagtttcata
    54241 cttatacaga atatacaata atattaatac taatactgtc attgaaacct ttataatcat
    54301 attctcttcc tctttattct attttgttaa tattattata atgcttttat gtttttttta
    54361 aaacaataac atcatcacat acatataaat cttttcgaca ttataaaaat aagttatcct
    54421 tttctaaaat tttcatttat tttagaaaag gataactata aaattatcta taaacctcta
    54481 tattgtgaaa tatagttttt cctttattta aatttttata tatatgctct aaagttccat
    54541 caaacctaat agaatgtcca gactctaaaa tataagtttt cccatccaca ttaaggtcaa
    54601 gtttaccttc tattacgagt acatactctt ctaaaacatg actatgtgta gatgaaacat
    54661 gagtacagtt ttcctcaagc tcaattataa aaagttcaaa ccttctttga gggctaaaag
    54721 ggtatattgg atataacttc atgttccctt tttgctcaac aataggctct acttcttctt
    54781 tctttataac ctcataggta tttgtatttt catttaatag tgtagtaaaa tttattttaa
    54841 atccagatga aattttccat aaagtagata ctgtcggact tgattcacct ctctcaatct
    54901 gtccaagcat tgctttactg acacctgtca tctttgaagc tttgtctaaa cttatgccca
    54961 tttcttgtct caataacctt aaattttctc ccacattagg aaatttatta tccatgttaa
    55021 aatcctcctg atagctattt gtattctatg atttttactc ctgtaagttc tactatctct
    55081 tttaatttta acatatgatt gttacaaatt tcatcaaatt catatatata atcttcaagc
    55141 cctaatgcct tatatttatc gattccaaat ttatgatatg gaagtaactc catcttgcct
    55201 cctggaacat tttgtttaac aaataatgca gtatttctta tattttcttc actatcattt
    55261 actccataaa taattggcac tcttataacc atagatttat tcaactttga aagcctacat
    55321 atattatcta atataatttt attacttact cctgtatatt ctttatgaat attatcatcc
    55381 atagatttta tatctacaaa tatgtggtct attttctcaa atacatcatt taccttattc
    55441 caatcaaaat atccacaagt ttcaattgca atatttatgc ctttatcata aaaaatatca
    55501 actaattctc ttaaaaaatc aatctgaagt gtaggttcac ctccagaaaa agttatccct
    55561 ccattagatt caaagaaaaa tataaaatct ttttcaactt cctctactat ttcttcaaca
    55621 ctcatttctt cggtcattat acaaatggca tctttaagac ataccttgat acactctcca
    55681 cataaatcac atttattatt tatttgcgtt ctatcaaata gtgaacttat attttgagga
    55741 caaacatcta tacatctatt acaggataca catttatctt tcataacacc taattttact
    55801 atgttactcc aggaatctgg attagaacac cacttacatt ttaatttaca tccttctaaa
    55861 aatatagtag tccttattcc atctccatca tttactgaaa aatgttgtac ttttacaact
    55921 ctaccttttt tactcataat ctacctcata attaaaaatt gctatgtgaa tttctagcta
    55981 ttatagcatc ttgcatttct cttgataaat taacaaattg agtactatat ccagcaaccc
    56041 tcactaataa atctttatat tcttctggat tttcttgcgc ttttaataga gtatcatttg
    56101 atatcgtatt aaattgtaca tggaatcctc ctaaagcaaa atatgattta atcatagatg
    56161 ttagatttct aagtcctctt tcagtttcca ccaaatcttg attcagtctt aaatttagaa
    56221 gtgttccacc agtatgaaca tcatgattta tttttgatgc agatttcatt gctgctagtg
    56281 gacttgttgt atcagtacca acaaatggag aaactccctc tgtcaaaggt tttgtcgctt
    56341 ttcttccaca aggagttgca cctactattt ttccagttgg tacatagttt gatataccca
    56401 taaatgcact attaaattta gagccaaaaa tatccttgta ttttctagtt tcagtataat
    56461 aaaaatcaga aacttcaatt gctaatgaat ctacataatc attatcattt ccatacttag
    56521 gaacatccaa cgcaagtttt cttaattctt cataaccttc ccaatcatta tttagtgctt
    56581 ttgttaattc ttctaacgta gtcaccttat cctcaaatac taattttttt atagctgcca
    56641 atgaatttga aactacacct aaccctatac cagttaatac aggacctata ttatattttg
    56701 ctcctccttt acttaaatca actcccttat ccaaacatcc atctacacaa gtagataaaa
    56761 atggtcttgg taccatttct ttatgaattt gttgagcaac agtagttcct ataacagaac
    56821 tttttacaag atatgctaat tgctttaaaa actcatcctt aagttcttca aaagaagtaa
    56881 attctgtgat attttttgta tctaacccca ttttttctcc agttaatcta ctcttacctt
    56941 cattcatagc atattctaaa gctgctgcaa aattgatatt tacggctgaa gtccactgtc
    57001 ctgtttttct aaaatgagga actacacaac cacagttact ccaatctcta gcatcttctg
    57061 catcatatcc atcttgtaat aacatttgtg cccctgcact atcgctgtgt atagcaggga
    57121 aaccagttcc ttgttttacc aatttagcaa ctgccattac gaaattatct ggtgctcctt
    57181 gactcactct aacacttaat cctggttggt gagtttttac actttctgta gcctttaaac
    57241 acatatatga gatatcattc gttccatcag taccatttct ctttttacca ccaacagtaa
    57301 gattttggaa ttgattatat cctgcaaagt aatttgctgt atttgctgat atagtccata
    57361 cccattctga taacttaatc caaagtgctt ctatcaattc ttgagcttct gattcagtta
    57421 ttttaccttc tctagcatca ttttcataat atggatacat atattggtca aatctaccta
    57481 aatttaatgc caatggattt tctgatagaa taccacctaa ttgaacaaac catacaaatt
    57541 gtattgcttc ataaaaatta gttggagggt ttgctggtac attcatacat atctctgaaa
    57601 tttttataag ttctaacttt ctcttttcat ctgtttcttg cttactcatc tcttttgcaa
    57661 gatttgaata tctttgtgcc aatgtcataa taccctgtgc aactatagaa acagatttgt
    57721 aaaaatctat cttttcaata ttttctgaaa ctgatatatc taattcttta atttttttat
    57781 ctgcatcttc cttaatccct ttatatcctt ttacaaacaa tatatcttga taatctggtg
    57841 ttacttcacc aactgcctgt ctccacttag aatcattatc tattattcct gtatctacta
    57901 atatcttagc tgtatcttct gggattcttg ctaagaaaac ttcttccaaa gattttccct
    57961 tccaatatgg aaatatttct tttcttataa attctatttg ttcttttgat attacatatg
    58021 ggtcttgagt tcttttatca aaagtatcca tttctttgtc tacccattgc caagaaaact
    58081 ctggtgtcaa tatccctgtt cttctaaatt ttcctgctgt acctactatt aattcatttt
    58141 caaagatttt tataggaagt tctttacatg tctccaaaaa agctttagct cttcttatac
    58201 agatagcttc tccctcagtt tttttatgtg attctgtaaa aattctagcc ctttcacaac
    58261 atatcatagg tttagaatta atatattctt gtctaaatgc ttctattcta ttagtttgac
    58321 tcatttaaaa tccccctttg gataatatat actacatttt tgtatgttat aacatacttt
    58381 aattatatta tactgtcctt tagcataaaa tggaagcaaa ataacttatt ttttttcatc
    58441 taccttgaac acctatatat taatactttt tttgttaaat ttataaaatc taaaaaaatt
    58501 ttctatgata tattttctat attgttatag ttatgtctaa tatactaatg atttgaaata
    58561 tcaaatttgt atactagact tagttttaaa accttagttg attgtttaac tttgttaact
    58621 tcaacatgta tatccttcat ataaggaagc tctacaacac ctactccctt attaaagtct
    58681 tcttcaacca tagaaaaaat ttctttctca gttaagttcg tattagtcaa tgatttaaat
    58741 aaattgtata taaatttaat atatttatca ctctcagata acttatcatc ttctggatac
    58801 tctttagcac agagaatatc tattgttact tttccttctt tatcgtcttc agacatagaa
    58861 tagaataaac ttcgaatatt tttttcaggt ggtttttcag caccatttat agatactaca
    58921 aagctaccat ctgattttga gttagtaata ctataaccac tgtctattat agctttcgaa
    58981 aatctttgag ataaatcttt ttttacttct tctctacctt tcgcatcatt aatcttttgt
    59041 gagtaattat taaatagctc gatagattca tcttttttat cttcaacttg ttctttcaat
    59101 gaatctttac taatttgttc tgagctactt aagttcttat cagatacagg agacatacac
    59161 cctaccatca atgctaagct aagatttaaa gccacaatta ttgccactct atttatattc
    59221 ctttttactt tcatacacaa tcctcccatc acactaaccg ctctaaagta ttattcattg
    59281 cactagaata tatttatatt ttctttatat taaagattta ttattcaata catatcacct
    59341 tcctatccaa ttcttataac ttactattag taaaatatta taagctcctt aatacagaaa
    59401 taaggatgtt atcttttgtt attaaaagat aacatcctta tttttttgta tcaatacata
    59461 tgtcccaact ggtaacttaa tcgccccaac tgtcagtatc ttggtccaat ggtatatata
    59521 tatttagtat aaatttatcg atactatttt caaataataa ttctccatta tatttttgta
    59581 aagaagattt aatactctga atacctattc catgtacgaa cttatccatt ttgtttgtta
    59641 acaatatatt tttattaaaa gtaagctgat ttagtttact attttcacat ttaagtacaa
    59701 aaaatgacct tgttatagtt cctttaattc taatatattt attaacattt tcatccacta
    59761 ttttatcaca tgcttctatt gcattatcca aaatattaga aaatatgctt gacacatcta
    59821 taggttttac aaaatttact tttgaaaaat ttatagagca agtaaattta attccttttt
    59881 ttaaacatat ttcactcttt tcgttgatta taatgtctaa tatcatattt cctgtattat
    59941 agatatattt aaatgttttt atttcatctt ttaaattgtt aacatattca ttaatttctt
    60001 tgctattgtt tctaaggttg tctatacaat aaatgtgatt atttatatcg tgatatagtt
    60061 tcttaactcg catatgagat tcttgaatac ttaaataatg cgcatattgc atatctaact
    60121 tattttttat taattcagct tgagatttta atctattctc ttttattatt tctttaaaca
    60181 atagtataag aaatatacta ctagctccta ccaattttgg attaacaaaa ttatcaaaat
    60241 agtatccttc tgaatgtaat gacccaaacc gttctaattt ttttaataca taatttacaa
    60301 gcatattcat tgtattaact aataaggcaa ataataaata tacataattt ctcttatctt
    60361 ggctaattaa ttttatagac tttctaaaaa agctaaatat aagatatata agaataatta
    60421 ttaaattact atatatctga atttttatag attctaagtg aggtactaat aaagattctt
    60481 tagatgaaat aacattacct gtaattgcaa aaaatagtat tctatatata acagcatcca
    60541 aacatttata atatacacta aatagataaa agaaaatgga atacttaata taacccatct
    60601 tataaaaata attatagtat cctccccaag caataaatgc taatatataa aataaatagt
    60661 ttatattact aaagtaattt cctccattaa ataatctact tatctgaatt ataatataaa
    60721 taagaaacaa gacaatatag aatactattt tttcattttt tttactatcc tttttataaa
    60781 ttaaaactcc gttcattata gaaaactgta taaatataga taaaactact aatagctcag
    60841 tcataaagtt tagcatattg tatcaccaag aaattttaaa aatttctcct taacttcttt
    60901 atatctatat ctactaatag gtacctcttc tccactttcc agtattgcag tattaggctt
    60961 tatattttca acatatctta aatttactat aaaactttta tggcatctta taaatttata
    61021 tggatttaat tctttttcta ttttgcctaa actatatttt atatcaaaat tcttgtttat
    61081 tgtgtgtatt agcatatctt ttttttgaac ttctatatat tttatttcat ttaaataaat
    61141 cttatatgta ttagacttat tttttattgt aatatgactt tccttattta tttcaatatc
    61201 tttgatacaa gttagcacat gtttttttag ttcttccaac tctattggct ttagtaaata
    61261 cctataagct cttacctcat aaccttcttg cacataatct attaatgaag ttacaaatat
    61321 tatttccatt tcattgtcta cttctctaat ctttcttgca gtatccattc catttagttt
    61381 ttccattttt atatcaagaa gtaatatatc tatatctttt aaattacttt ccagtaactc
    61441 ttctccagat atatactttt gtatctcata ttctatactt atatctttta atatattctc
    61501 aaggtaatct tctattaaaa gttgtgtttc tttttcatct tcacaaactg ctatcttaat
    61561 cataaaatgc ctccttacat aatttctagt taatacaatt aaaatattta taatatattt
    61621 aaagataatt ttgtatatct gatactttag gataacattt ttaaattatt tttatcaata
    61681 ctcaatccca cacaactatt atttgatatt tcaatttaaa gacagaaatt actataatta
    61741 aaaacagtac ttactgacaa aagaagatgt cttaaaatat taaaaaaata attttaggac
    61801 accttctttt atttatttaa actttttaag ccttaaataa tacattaatc tcctatataa
    61861 ttgtactgca tataaaatca acaatataat ctgtagtaca atagcagtta cagatgctcc
    61921 ataaccacta tataaatttc ttatttcaat attcaataaa tatataaata ttactactaa
    61981 cataaagaat ataaacatat tcataaataa aattgacttt actttatttg ttttatcaga
    62041 atcactatat aatttaggag gtatgtcttt gtattctttc gaccatatat accatgcaga
    62101 tgtacccata aaactaccaa tactcctaaa tacaagattc cagccatttg atttatgttc
    62161 atcaaaataa ttattctcta catcatagta gtaatcaaca gtgtatttta tttttcttgg
    62221 acttccctta tgaaaataaa atattcctcc aaatttattt atcttatata aattatatcc
    62281 tttagcttca atatcttcta accatttctc tatcttatca ggtgaactat accagtcaaa
    62341 tttgaatttt attttctttt ccatagcact cattctccaa aatgatattt ttaaatagct
    62401 taaaaatcta tttaaataat tatatcattt tgatactaat tttaggttac aatcatatat
    62461 ttaaaaagct atttaaatag taataaacta atagccataa cacccattcc tgcaatcaat
    62521 ccataaatag ataaatgatg ttccccgtac tctctagctg atggcaataa ttcatctagt
    62581 gatatgaata ccataattcc tcctacaatt gcaaatacaa ttccaagagt tatatcattt
    62641 aaaaaatttc taagaagtac atatccaata atcgctccta aaggctcaga cataccagat
    62701 aaaaaggaat aataaaaagc tttcttttta tctcctgtgg cataataaac tggtacagat
    62761 acagatatac cttctggtat attgtgtatt gcaattgcaa ttgctatcgg aatagctatt
    62821 gtaacatcat caagagctga tataaatgta gctaatcctt caggaaaatt gtgaattgct
    62881 atagccattg ctgtaaatat acctgttctc aaaagagact tatttttttt gatattcttt
    62941 tcttctatat tctccatttt ctttatttca tgtggatttt cttcttgtgg aattagctta
    63001 tcaataacag caatgatagc catacctata aaaaaagcta ttacagttga ccaacttcct
    63061 aatttctctc ccatagattt tgtcaaagca tcttgtgctt taggaaaaat ttctatcata
    63121 gaaacataaa tcataacacc agcagaaaat cctaaactta tagaaagaaa cttagtattt
    63181 gtttttttag caaaaaatgc tatacaactt cctataccag tagataaacc agccaataat
    63241 gttatcaaaa atgcaaatat tacattattc aaataaatca ccttcttttt aattgatatt
    63301 gattatcatt ttctttatgc tatcatatat attttatata gtcaatattt ataaaaaata
    63361 tacacaataa aaaagcagag atataaactt agtctctgct ttttctttat agtatattaa
    63421 aattatttat ttaagaaatc cactgcatat tgcacgtata aagcagttcc aatttctaga
    63481 acatcttcat ctatattaaa gcatccatga tgatgaggat aacaagcacc ttttgactca
    63541 tttctagctc ctacaaatgc tagtgcacca ggtgctatat tcataaactc agctaaatct
    63601 tctgctcctg ttactttttc aaatagtgtt atacagtctt ctccaaatag cttaattgct
    63661 gcatctgtag ctatctttga acattctttg tcatttataa ctgctggtgt taagtaccca
    63721 tactctaatt cagcatctgc tctatatgct tctgctgtag attttgctat acgttctaaa
    63781 attccaggaa tttgctttct aagctctgga ttaaatagcc ttattgtacc ttctaagata
    63841 gcttcactcg caattacatt aaatctagtt ccagaattta aaactccaac actcacaact
    63901 aatggttcca gaggacttac ttctctacta accatagatt gtagattcat aactattgct
    63961 gaacttgcaa gcactgcatc aacaccttga tgaggaagtg aaccatgacc acctctacct
    64021 tttacagtaa ttttaaagaa atcagcagaa gccattcttg gtccttcttc taccgatatg
    64081 gtcccagatt ctacatcagt ccaaagatgt attccaaaca cactatctac accttccata
    64141 gcaccatctt gaatcatagc tcttgcacct ttaccaactt cttctcctgg ctggaaaaat
    64201 aattttacag ttccattgat actatcctta atatcattta acacttttgc tgcccctaga
    64261 agcattgatg tgtgaccatc atgaccacaa gcatgcataa gtccttcatt tttagatttg
    64321 tattctacat cagtgcattc aacaacttgt agagcatcca tatcacccct aagtgctaca
    64381 gtctttcctg gattagctcc ttttatagtt gcaattacac ctgtacctcc agctgataca
    64441 tatggtatcc ctattttatc aagttcttct ttaactctct ttgatgttct aacttcttcc
    64501 atacttttct caggattttc atgaaattcc cttctaagct taattacata gtctttataa
    64561 ctcttcgtta tttctttaat atccattcca tacctccaag tagtacacat tcttcttatt
    64621 taaaatactt tttatcactc aaatactata ttagatttac aaagatacct gctattacta
    64681 cagaagctat tgtaactgta gtaaatcctc caacaagcat ctttggaagc atcttatcca
    64741 ttaaaaattc tttttcttct ggtgtttcag ccaaagcctt tactgcctct tcagttaata
    64801 tatagtttgg tggaaaacca taaagtgatg taagcgaaac tgaaaaagcc atttctttac
    64861 tttcacctaa aagcttacct actataatag agaatattcc catacctatt acaccaaata
    64921 ttatgattcc tacaagagga actgccattt caacaagcat tgctggtgta gcttttgcta
    64981 accctgcaaa tataaaagcc atcaatgatg tcattaacca tccaaatgaa ccagatttat
    65041 taagtggttt tctatcaact attccaagtt ctgatgctat tacaccaaat attaaacata
    65101 taacatatct tgatacaact tcatttgtaa gatttgtaaa ttgtactgct aaccatgcta
    65161 caaatcctaa tctaagtatt atcatatatg tcgtatcata tttttctggt aagtctggta
    65221 ttatcttaaa tctgcttttt tgttcaggta aatccttaac tttttcttca tctgtattta
    65281 cagttacttt tccacttcta aagtctgata aaagtctttt tccttctttt ttaagcatta
    65341 atgctgtaat aggataaccc gcaaatcctt gtgcaacata catcaaaatt gcaagtactg
    65401 ataaacttgc aagacctttt gctgtagcag catctgccat cattatagat gcaactagcc
    65461 ctccagtaag aggaggtgta gctattactg ctgtatccca tccaaatact actgtcccta
    65521 atgccaaagc acctacacat attcctacta ttcctgccaa ggctattact attgttttcc
    65581 attgacctgc taattcctta atactcatca tagttcccat atgagttatt aacaaaagca
    65641 tacctaattg agctaatggt gttcctaaag cggctaagtc cacaatattt tctgggaaaa
    65701 aagtccaaaa tcctactata aatataattg ctgatacaaa aaccgacgga acaaaagctt
    65761 tagtttttgc tgaaactata tctcctatcg tcagtgatac taaaactaga caaaaagctg
    65821 ttattgcctc catacaaaat cccccctcat aataaatata tttttataaa atgtatgtat
    65881 agttatccat tattttacta cttttgaaaa acatttcaag tcaaaattcg atttttttca
    65941 taaaattcga taaattccat aaattaaagt tagttttcta aattattctt tttgtaaaaa
    66001 cgttatcccg accattggct atttaactct attcttacaa agagaattaa atgtaatttg
    66061 caaaaaataa aacataggat acattttatt cataaaacat cttataaata taaaatgaat
    66121 tgtctttatg aatcttaata tatcctatgt ttgtaagttt aatgtgtatg ttagctatgg
    66181 tgtaaaattt gtatactagt tattgtgtaa cctactatat actccatttt tgtttactag
    66241 ctcttcatga gtacctcttt cttcaattcc tttatccgtc aatactatga tttcatcagc
    66301 attttttata gtagtcaatc tatgtgcaac aactaaattt gttctatctt tacttaattc
    66361 ctctaaagac tcttgaattt ctctttctgt tacattgtct aaagcagatg tagcctcatc
    66421 caatattatt attggaggat tctttaaaaa gattcttgaa attgaaattc tttgtttttg
    66481 cccacctgat aattttacgc ctctttctcc tatataagta tcatatccat ctggcaaagt
    66541 ctctacaaag tcatgtattc tagctttttt agcagcagct atcatttctt catctgtagc
    66601 attagggttc ccacaaagaa tattatctct tatagttcct gtaaataaaa atacatcttg
    66661 ttgaactata cctatatttt ttctcaatga ttttaaacta acatctttta tactctttcc
    66721 atcaattttt atatcaccct tatcaaattc ataaaatctt ggcaatagat tacataatgt
    66781 agtctttcct cctccagaag gtccaactaa tgctatagtc ttaccagctt ttatagataa
    66841 acttaaatta tccaaaactt gagtcttatc ttcatatgtg aaagatatat tttctatctc
    66901 aatgtcacct tttacatttt caagttcaat aggattttta gcttcttttt gatggtcttg
    66961 ttccattatc tctatgaatc ttttaaaacc tgtcatacca ttttgatatt gctctgtaaa
    67021 gtttattaat tttttcatag gttgtataaa catttttaca tatagtatat aagcagcaaa
    67081 atcacccaaa gtaatctttc ctatataagt aaaataacca ccagctatta caactaccca
    67141 ctctaagata tccatgtata aattcatacc agagtaatat tctgccatta ccttataaga
    67201 atcttgtctt gctcttctaa ataatttatt gcttcttaca aacttattta actcttcttt
    67261 ctcagtacaa aaagacttag ttaccttcat acctgctata ctattttcta aagtagcatt
    67321 tacatcacct atagtaactc tactcttcat aaaagcaata ttcatcttat cttttttagc
    67381 tattgcaaac caaattataa acggtaatat agcaaatatt ataagcgtaa gaggaatatt
    67441 tatatctata agtataaaga atgaaccaac caacattact atagaaatga ataaatcttc
    67501 aggcccatga tgtgcaagtt ctgttatatc cattaaatca tttactattc tagacatagt
    67561 tactccagat ttgttattat caaaatacgt atttggaagt ctttgtaagt gtgtaaatac
    67621 ctcatttctc atatcagctt gcatatctac accaataaca tgtccccaat actgcataaa
    67681 atagttaagc cctgcttttg ctataaatat aagtataagt gctactgcaa aaactactaa
    67741 cattcttaag tttttatttg gaacaacgtc atccattata tttctagtta tcataggata
    67801 aactaaatca cataaggaaa atagaaaagc tgctataagg tctagtgtaa aaattttctt
    67861 atatggctta taatatttga caaattgttt tatcataagt attaaatccc tcctttatta
    67921 gtacttctaa aaaataccca taaattagta taacataaca ataactttaa atcttttata
    67981 aacttacaaa gtaataacaa tctttttcat aaaattgaag atttatatca tatagttgta
    68041 tacttgaaac aacataaaaa gagctatatc tctatattta aaattttata aagatacaac
    68101 tctatattta atactaaatt ttttttataa atacaaaact acttcaatgc atttaatatc
    68161 tttttatcta atgctgttgt atttatacct gttatatatc ctgttgcctt tattgtaggt
    68221 atatcataag ttgttggtag tatagtagta gatacgatta aatcagcacc ttcttgtttt
    68281 gttgaacatt cagcaatttt acattgctca acttctgctt gtatattatt ttctttaacc
    68341 aatctttcta ctctgtcaca aactattgtt gatgttgcga ttcctgctcc acaggctact
    68401 aatatttttt tcatatattg tcctcctaca atttctttaa tattttataa ctcaaaataa
    68461 aattgataaa tttcttatat ctttatttat ataaataatt atatcatttt atataagaag
    68521 aacatcttaa aattattctt ttaatatgtt ttttatttca acattgctta tacttaaaat
    68581 ttcatttttt atacaagact ctatgtactt tgatatattt ttataatcat ttaaattaaa
    68641 ctgttcaata ttcaatttat attctatatc actgacaata cctatcaaat cagacttatt
    68701 agataaaata tcctcatact taccttttct agttacttcc aatcttttaa atctataatt
    68761 tttatatcct tctatgataa tcaagtccat atcttcatat aattgaatca ttttatataa
    68821 tggattcttc tcttttagtt cttcaatata tgctactcgt ttatctgata ttatacagac
    68881 ttttctcgcc ccagattttc tatgtttata agtatctttt ccttcctcat ccatatcaaa
    68941 atcatgacag gtatgtttaa taactccaac acgataccct tttttattta attcttttat
    69001 tatgccttca atcaacgtag ttttacctac tcctgaatat gagacaactg acaatatatt
    69061 atacataaaa ttgtgtcctt tcataaaact atctaataac aacatccact aattgatttt
    69121 cttttattgt ctcattcttt ttaatcttaa tcatacaatt acttcttaga gttgcagata
    69181 atctagcttt tgcatctttc ttatcattta gctctacata caatttacct tcacttgtat
    69241 atagttttcc acttacaaat ctatctttat ttgaaagttt attaaattct cctttaaata
    69301 tagcttttat atgatgtgtt cccttcttat atgttaaatg ctcaataaca ggaactatca
    69361 cattatcaaa taccactatt gctgcatgtg gattaccaga aagaccaaat aatagctttt
    69421 ctcccaatgt acctacataa caagctccac caggtttaat gtttatcttc caaaataatt
    69481 ctgttgcccc tatttttttg aatacatctg gaattaaatc tttatctcca acagaaacac
    69541 cacctgtggt aattaaaaaa tctacactct gtaacatatt ctttaccttt ttttctaact
    69601 ccaatatatc atcagaacaa ttgcatattg tatctgcttg tattccaagt tttaataatc
    69661 ttgaatataa ggtatatcta ttactatcgt atattttacc attctctaaa gtctcattta
    69721 tatcttgtag ttctgtacct gtattcaaaa ttccaacttt taaatcatca taaacagtta
    69781 ctttggatat tccaatactt gctaatactc caataccatc atatcctata ttctgatttt
    69841 tattaataat caattgcccc ttttttatat cctcaccctt aaatatgtaa ttatcgtatt
    69901 cctttaattt tatatttaaa gttatcatat cacctataac tgttacatct tcttttttta
    69961 ttacacaatt tgcaccctgt ggtatctttc caccagtcat tatcttcact gcttcatttt
    70021 tatttaatac cctattaaat acatctcctg catacaaagt ccctataacc tttaaatttc
    70081 tattttcaga atttgcatta tatgcataac catcataggg tgacctatca aatggaggac
    70141 tatcaattgt tgaatatata tcttctgcaa ctaccttatt tactgcatct ataagattta
    70201 ctatcttgac cctgtttatt ggtaaaacat ttttttcaat aatttttatg gcatcttcta
    70261 attctatcat tttaaatact ccccaatata ttttttattt aagatatttc tatgtaatat
    70321 attatagatt ataaaagttg gaaatacttt tatcttatat ttaattataa ctaatagtta
    70381 tctataagtg cagttcaaat tttataaatc taataaaaaa actgttccca gctagaaatt
    70441 tccttctatc ttgaaacagc atcatatgct ttagaatatt ttattctaat aaagttcctt
    70501 ttattatttt tacaatttta tcactttcaa tagtttttat agattttatt ttgttatcca
    70561 caatacttat tgtaagtacc tcttttttta atattttgtt atcttctttc aatctataac
    70621 tcttaactac tttactgcct tcatgattat atgctgttaa atcataattc gcatctccta
    70681 caatttcatt tattctggaa tcttcaacac caacatactc tcccaggtca atatgtctaa
    70741 aattttctag tgatacagcc gatttttcat ggtcactttt ttcaatcact atactagatt
    70801 cagcatcaat gactgatata ccttgtgatg aaaaagaatt ggtttcaaca ttgacaactt
    70861 tattttcgtt aatatcaaca tataaagcac ttccatctag ttcatcattt ccagtatatt
    70921 ttggataaac taatgtcata taacttgatg tatttatatc ttgcattgta tttgattctt
    70981 ttaaaacttt aggttttata taataaaatg tattataagg tatacccata ttctttataa
    71041 tgtacttata atctttattc ataatttcat taacatcatt ttgaactttt gtcatagttt
    71101 tttgctgtgt tgctttactt gctacttgat ttttctcttt agtattttct ttatgacatc
    71161 caacaagtat aatacctaaa atagttacac aaactaatga cctttttaac ttcataaatc
    71221 aatcctcctt tcttaaattt tatagtattt atctatatct caatttacag ttatctcttt
    71281 tttcaataat tatatttatt atattataaa ataattatat aatatttatt tgaatttaat
    71341 aagattaaga agctaattgt aatttttctg taataaaaaa cactttaaag ttgaattttg
    71401 aaaattcaat ttacgatatt tttattgtaa gtaccttaca acattatacc aaattattcc
    71461 taaacaatca aaaactccat gaatatttaa aggttttcta ttttaaaaat cacctttgac
    71521 tattaattta tcaaatatgt tataatagtt ttagataatt taaggaggat taaataatgg
    71581 attttaaaca acttgaagta tttgttgctg ttgcaaaaca tcagagtttt tcaaaggctg
    71641 caagagaact ttttttaact caacctactg taagcgcaca catacagaat ttagagagag
    71701 agctagaaac tgttcttata aatagaagca acaaagttat tacactcaca aaatctggtg
    71761 aaattcttta tgaacatgct atatatatat tgaataattg caaacgtgca atttatgata
    71821 taaaagaata ttcaggaaaa atagaaggta tcatagatat agcatgtagt tccatacctg
    71881 aaacttatat tttacctgat tttatgaaga gtttttctat gagttatcca gatgtaaaat
    71941 tttccataag ccattatgat tctcaatatg ctatatcaga aattttaaat gaacgaataa
    72001 gctttggatt agttggttct aaaatcaata atcctcaaat agagtaccta gacttattag
    72061 atgatgaact tgttcttatc actccttcag attttaaaat tgataataaa aataattgta
    72121 tcgatatagg agaattggct tatctaaatt ttattatgag aaaagaaggg tcaggtacaa
    72181 gaaacttaat actaaacaca cttagtaaaa ataactttcc agtaagtaaa ttaaatgtaa
    72241 tcgctcatgt agaatcaaat gaggctatta aggaaatggt tagattaggt cttggagtat
    72301 cctttatatc gtacatttca gctattgatt atctcaatgc aggtaaaata aaatgttata
    72361 aaataaagga tgttgatttt actagaaagt ttttcttcat ttactctaaa aagaaaactt
    72421 tttccccatt agaagataaa tttctaaaca gattatgtga gtatttcgaa attataatat
    72481 aataacttta ataaagtagt gcttaatttt gagtttataa ctaattaata agctaattat
    72541 aactatcaca taaatgctta taaattatta tgaaccatct ttctttttta tttaatttag
    72601 tcaaaaaatc cctcgttcaa atgaacttgg gattttttta tttatactac tccaatagca
    72661 gccaatacta tacaaataat cataactgaa attaatatcg tagttgtctt tacctttttt
    72721 cctaataacc aatacataat accgaatatc atagctggaa gcatacatgg cattatttgg
    72781 tctaagtaag tttgaatagg ctctgcccat tctccactac ctacattaac actaagtttt
    72841 aacattacat tagatgcagt catacctcca attaccataa gccctaacat tgaagctgct
    72901 tccataactt ttgaaactat acttgaacca ctcacatctt taaagaattg agttccatac
    72961 ttaaatcctt tatctagaca tatatagcgt ataataaaat gaggaacatt tattattaaa
    73021 aggaataaaa tcggtcccat tatgttaccc tgagaagcta aagctatacc aaccccagct
    73081 gctataagct ttaatgttcc ccagaaaaat gaatctccta tcccagaaac tggacccatt
    73141 aaacttgatt taacagcatt tatactatta gcatcaaatt ctttattctt tgcattttct
    73201 tcttccatag ctccagatat acctaccaaa agagtactta tatgaggagt aactgacata
    73261 aattctaaat gtctttttaa agccttagat ttcttttctt tatcatcttt atataatcta
    73321 cggattattg gtgccatcat gtatgcatat gctatatttt gcatacgttc gtagttccaa
    73381 gatgaatcta atgtcaatga ccttctaaaa catttccaaa agtctttcct cgttatttta
    73441 ctatctggtg aaattgtctc taacttctta gaactcgttg tcatctacta ttacctcctt
    73501 ctctcctaca aagttaacat atattaaagc tattgctaat ccaaacaatg caactcctgt
    73561 tactgttatg tttaggtaag caaccaatat aaatcctaat aataaaaatg ctactgtttt
    73621 cttattaagc atcattctag ctaacatggc aaaacctatt gctggaatca cgcctgctgc
    73681 aacatccatt ccatgagtta catatgatgg tataaatgaa agtatttttt ctattactgg
    73741 aacacctaat gaaaatccta tacctactat tattgctaat attaatttat ttcctatacc
    73801 aaataataat tgcacacgtt ctacgccttc aatattcccc tcttctgcat aacggtcagc
    73861 aatatgagct ccccatgtaa gtactactgt cattaagaag ttatctataa gcaatactag
    73921 agttgctata ggaactgcaa gtacaactgc tgctgataca tcttgacccg ttaatattac
    73981 aaacgctgtg gcaataatag aaccagacac aaaatcagga ggattacttg ccccaacagg
    74041 aaatgcaccc ataaatacta attctaatgt tgaacctatt actatacctg tatgaagatt
    74101 acctagtgct aaaccaacaa gtggtgcaac aactataggt ctattatgca ttgtagaacc
    74161 tacaaaacta tgcatatatg caaagaatgc aattagagtt atcaaaataa cttgtgtaaa
    74221 ttccattttc atccccctaa aattatatta atttcattac atttgtagca tcatcatcag
    74281 gaactaattg tacaaataca tttacgcctt ctgaatctaa ctctttaatc atctttatat
    74341 catcttttga tacatgcact gctttagata tattttcacg attatcatct gattttgttc
    74401 caccaaggtt tatagattta atagctttta cctctttagc aagtctgtaa acatcttcta
    74461 cagattcaca aagtatcaat aagttgtatt tatcagtaac acctgagtta agtgctttta
    74521 tagaatctgc tatgcttttc attactaact taacattaga tggtttagcc attttaagtc
    74581 ctgccattct taattcatct tttaataagt catcacttgc tatcaatata cagtctgtac
    74641 ttaaaaactt tgtccatgta aatgctactt gtccatgtat aagtctgtgg tctactctta
    74701 ctaatttaat cattataatt cctccctaat ttttttgatt tcatccatga atgtttttac
    74761 gtgttctaca ctaacatccc caaaatcttt gtaattatct ttaaagtaac ttcctattat
    74821 tgccatatct cctaatttaa gctgtttttt tgcattttcc aatgtaactc cagcagctat
    74881 aaccaatggg aagtctccta aatttttacg aaacagttct attttttcca ttgatgtttc
    74941 ttgacctgta gcattttctg taactgctat agcatcacat cttgtcattc ctatttttaa
    75001 atcttcttca acatcatttt ctgataatac tggctgatat ttaaaacgta cgcctccaat
    75061 taaatacgct gggcattttg aacgttgtaa tttaaaaaac tcttctaaag tagcttcatc
    75121 tctaggttta acatgaccta ctacagaatc aacctgtata taactagcat tatattttgt
    75181 tgccagttca aatcccatag tatcaacatt taaacagttt actccatatg gtattgataa
    75241 attagctttt gatacatatt caagtattct ttctaaatca taataattac catagtaatt
    75301 ttctaacatt attccatcta caccattttc ttcaaagatt gtaatctctt ttttagctct
    75361 ttcaaagata tcttctggag tatctccttt taagtgtatc attgctataa ttggtttttt
    75421 acttttaaat actgataata ttcccttttt tttcataaac taaaatacct cttcttcttc
    75481 tttaatttgt aatgtcacgc tttgtatccc tcttctagat tcttccacta attggtctat
    75541 atcttcaact gttaattcat cagaaaacct tgtaagaagt tctaatacca tattcaaatt
    75601 cattccagaa aataacctaa cattatgtag attagttaat cttaacattg ctgtacatac
    75661 acttgctcca tataagtcag ataaaattat atattcacat tctttatctt ctgatattgt
    75721 tttttctaat tctaaagcaa aatctgaagc actttgtcca gggtacaaac catacgaact
    75781 gacacaatct gctaaatctc ctactatcat ttttactgca tttaaaagcc cttttgaaaa
    75841 gtctccatga gatgctaata ttatcttttt catactcatc ctcctactaa attatagatt
    75901 atatttctgc tgatactgca tatttgtact tatcacttct tataaattgc tcattgtaat
    75961 ataagacatc attattttct gtatacaccg attgtcttac tttcaatagt ggcatattac
    76021 ttgcacattt aagatggtca gaatattctt tgtttgaatg ttttacttca aatatatttt
    76081 ctactcgttt aggtaatgtg cttatattat tagatataac ctccattaaa gatttatctt
    76141 ctaattcttc ttttaataaa aacatgtaat ctattctaaa atagtcaact tcaaaaataa
    76201 caggtacttc atctattaat ctaagtcttt taatacatat taccttctct tctagttcaa
    76261 tacttaaagc ttcagctact tgcttatctg ctttttttat taaaacagag attattttgg
    76321 tacttggttt tgcattaata cgatgacaag aattagtaaa actatttcct gcacatgttg
    76381 cttctattct ctctggtatt gttacataag tccctttacc acgtttttta cataatatat
    76441 cttcttttac aagttcatta agtgcatttc tcacagaaat tcttatattt tatttatgtt
    76501 tatttatatt tatttatgtt tttatgagta catttattta caacctatct aaaacaattt
    76561 ctttattcta ttttatttat atttctttat ttgtatttta ttttattaaa ctgtcatggt
    76621 ggcaaaaaag gtggcaaaaa taatttgcca cctaaaataa tctttattta ttctttctct
    76681 tttaaatttt taaaatgttc ttcgagttca attaatttat cttcatccac ttcatcatct
    76741 ttactatgta acgctgatat taaacttgaa attgaattct tatgtatgtt cttcaaaaat
    76801 tcctttgttt caaatcttag atattttttc tcttttacca ttgcattata gtgtgtaagt
    76861 ttacctattt tctctgtact taaaaactcc cttcgctcta acctttttaa aactgtgaat
    76921 gtagttgatt cattccattc gtatttttct tccattgcgg caactaattc cctagacgtt
    76981 aatacatcgt tagcttccca aatatatctc ataactttta attctgcttc tggtaattta
    77041 ctaattttca tagtcacacc cctttatcga attatgtata tgttaaattc tatctcaata
    77101 aagttttcca aacaagagaa tcacactaaa tattaccatc caattttttc catctcgaaa
    77161 ttattcttct aaatttctat aatattcttc taatgcgtct agtttttctt tacttataga
    77221 cttatgtgta gtagtaagag aacgcattat ttttctgctt ttgctagatt ttaacacttt
    77281 tttcttaaaa gcataatatt ctttgttatc tattattatt ttataatgag attgaaactt
    77341 tataatatct ctggccaaat aacctttgtc aactagcctt tttagtagta tttttattgt
    77401 acttttatgc catctataaa cctgtctcat ttcttttaca atttcttttt tagtcactag
    77461 agaatctttt ttccataaat actccattac tattaattct gctcttaata atttttctac
    77521 taatatttct tctttcaact tatgtcactc cttcgattgt tctagttcaa gttaataata
    77581 agagcttttt aagacaaaaa ctataggtaa tttttaccaa atattctact gttttagttt
    77641 gttttcttag aagaaaaata actttcatat ctatagaatt attcaatttt caaactatcc
    77701 tgttgaataa taactaattc tattgtatta ttttagttgt agaataaaac taaatcggca
    77761 aaactagaga aatttagtga cgcaaagcta tagggactaa gatttataaa attcttataa
    77821 attatgccag ccagttgcca aaaagatatt gttctttttg tttttatgaa agttttttag
    77881 gtggctaata atatatatac ttagagataa aataaaatat atttctagca ttcacagttt
    77941 tattttttct taaaatgcga tataataaag atgtaaattc gtatcaaaaa caaaaaaaga
    78001 aactacaatc tattagccta gagcgaagtt tcaaattcaa aataatttaa gtaatgattt
    78061 attcattgaa atcgtcttga ttgccgtcag gacgatttct tagtttatgt aaagattctt
    78121 ttaatctact tatagaatct aataatcttg ttatagactt tactattgtt gtaatagatt
    78181 ttattacaat agtaatgtaa tacgctataa caagtataaa cataagtgtt ttcatatact
    78241 cacccccttt cgttcgaagg tgatttccga aaactttcgc ccttagattg tagcctcttg
    78301 caagatatat tcttgcattt taattataac ataattttac aattatcaaa tatctattct
    78361 ccattttttt atttatacaa tatattctat attgcaataa aaaacattgt tttaaatata
    78421 tatacatagg tatatactaa atatgttaaa cttaattatg gaaaatataa aatgaaagga
    78481 ataaaaatat gactaagact atattatgtg attactgtaa taaaggaata aataaagatg
    78541 ataataagta tattactttt cataagaaaa gtcatatgaa aactaacatt tgtattaatt
    78601 gtgcattaaa tttgatagat aaagataaat taaatgaaaa tattataaat aatcaacatg
    78661 attattcaaa gaaatgaaaa agcactctcc ataatgaaga atgctctata taataatgtt
    78721 tgacttagta aagatgtgtt ggggttacat atttactttt ttattatatc atataacttt
    78781 gtgtatgaaa aagaatttaa atcaatttta aggtgtgttg agtaatattc ttgatagttt
    78841 atatgttgat gaatttcaaa aaaataagca ctcttataaa aagagtactt ttggtatata
    78901 ttcaagcatt tatctaatac aattatagca tgtattatgt tttagtatga taattttcgt
    78961 tcgttttatt attacaactt ctactatagt tttcatactt taacatcaac taaatgaatt
    79021 taattaagat tactagttaa tcgttttttg gttctttcat attctgaaat ctaaaatttt
    79081 attatttgtt tattgttatt atttaacaca tgttggtatt tcaacgattt atcttattgt
    79141 taatattctt attgcttcca aagtatatct aattattttt aagataattt actaattttt
    79201 attttttcaa acatacattc gacaaaaaac agtttttata tggtataatt atattgtata
    79261 atacaaaagg ttaatgaaaa taattaatat taaatgtacc aaaaaaaata gtttttgata
    79321 taatgaatat tataataaat aattatttaa ataaaatatt atataaggat gtgattttat
    79381 ggatttcaaa atcagagagc taattaatga tataacccaa gatattatcc aaacatacaa
    79441 aatccaaatt ccaatagtaa atataaatca agttgttgat gctttaggag gcaaggtaat
    79501 agaagatagt tctttaagtg gatactctga tggatttatt agaaaagttg atgattcatt
    79561 tgaaatagtg gtatctcctt atcaaccaga taccagaaag aattttacca ttgctcatga
    79621 acttggacat ttatttttac acatgggtta tggcattgat gatgaactat ggaatagtca
    79681 agatggaaat cagtatttta gaagtggcaa taccaataag gagtatcaat ccaatgaatt
    79741 tgcagcagcc ttgttgatgc ctaaacatga atataaaaga attatggatg aaaacacagt
    79801 aggtaataag gtcgacactt caaaaattgc agaatacttt aatgtttcct cttatgcagc
    79861 atctaataga gggaaatggt taggatattt acaatggtag atgataaaga atataaaact
    79921 caaaatgtaa ataatgttca taattcagct aaaaacgaaa acgcttttaa tcttaaaaag
    79981 tataaggaaa aacttcaaga aaatattaat actgatattt atgaaaaaga aaaagaacct
    80041 aatcatccag aagtgatttt gttcttttct tttgatatag ctaattcatc attatataaa
    80101 aatataaatt atagcggatg ggctaaggta ttatcacata taattcgtaa gttacaatat
    80161 agagtttatg aaaaccttaa agcacaactt tggagagttc ttggtgatga ggtaattttc
    80221 attatcgtac taaaaaatta tgatgaaatt tataaataca tagatataat ctttgatatt
    80281 ttaacaagca ctgctaaaga tataaaaagt ggtaatatat tctctacact agaaggattt
    80341 tctgaatctg aaaaatactt aatgaaactt caaaatatta tttcattaaa aggagcggcc
    80401 tggattgcta tagtatcaag aaatcctaat tttaatgctt tagaaaataa tgaacaatat
    80461 gaaaatattt ctgctatgta cgatttatcc aataattata aaatatttga gttcttagga
    80521 aatgatattg atgctggttt cagaatatca aagcaaacat gcccagaaag acttgttctt
    80581 agttttgaac tagcttatat attatcaaga aaaactgata ttttatctaa attacatata
    80641 attacatata aaaaattaaa gggtatctgg aaagataaac tataccctat catttggtat
    80701 cataataaag gaaaaaataa tgatatagaa tttgatgata gtttttcttt tgatgaaata
    80761 gaagaaaatg aattggttcg agaatatttt tttaataaaa aaggagaaag taaattacta
    80821 attgattctt ttatgtttaa ttctgtagac aaggctttgg ataaaatact tatagacaga
    80881 aaccttagtg ataagattga aaaaataggt gacgtaattt ctaaaacaaa ccccagttat
    80941 gataaaaata caatagataa agactatata aaagtagatt taatggaatt acactgtgtt
    81001 gcggtttgtt ataataaatc aacttcaaaa atattaattg cgaaaagaag tgataataga
    81061 aataataatg cgagtaaatg ggaatttggt tgtgctaagg caagtctaga aacttcaatt
    81121 ataaatacta ttaaagatga atatgaaaaa gattttaata taaacattga acctattact
    81181 gattgcacaa gaaaagatga ttgccaacct atacctctag caatttatca agttaaaaaa
    81241 agtgatggtt tacacaaagg cattataact ctcgcagaaa taataaatga ttatgatatt
    81301 tctaaatttg aacccacatc aaaacataat gaacttgcat ggataggaga ggatgaactt
    81361 gaagatttta atgaaaacac agtacctgat tttaaagaaa ctttaaaact agcatttaaa
    81421 aaattaaatg aaaatcaatt acaagaatct acaaatatgt aaatagtatt cttctatgat
    81481 ttgattctat cttcatagag gaatactaac caaataaaac attttctaaa tagcattaaa
    81541 aactactaca agtatatata taaacaatat aataccacct aaaataaaag cttctactga
    81601 cttttttaca ttatacattt tcttatcaca gattaaagat aattctttta tttgaacaag
    81661 tgcatcatta atcaagtttt cttcgtcttt aaatgcattt tcaaatgctt ctttgtactg
    81721 ttcattattt aaagatgcta tctctttata ataaaaaata gatttatatt cattttctat
    81781 tttagaattc cttggcttta aaaccataat cgaaaaataa attgaaataa caaatataca
    81841 taatataaca atgtaaaata gcatctctaa acatctgata ttacttatac ttaagtgatt
    81901 cattattttt tccttccctg aaaataaaaa acctataatt gcactattta ataatagtaa
    81961 aaaactagct ttattatctg atttttcaat atagtaatca attctattta ctataaactt
    82021 cgctatgtct atttttttat ccatgatttt actacctcat ttcattaaat tttatattga
    82081 ttcaaaattt tattttctac ttattatcat tgaataaatt attatttgga aataatctta
    82141 ttgaaataat aaaaatatgt gaaagaaagt aataactaac tataattact acttcctaac
    82201 ttaaacattc tatctcttcc aattaaaagt aagatatcgt cctctataag tttcatattc
    82261 tcttataata tccaatattt cctccctaga agttgcaatt aaacttctat caaatagttc
    82321 aatcattcta ttgctatcat tatcagaaac attacaagac tctaatatct cattattaaa
    82381 tattgcaata gcatacccag tacctatttt tatctcattt aattcatgta aattatttgc
    82441 tgctctaaag atatcagctt cagccaatcc acctaaatct tcgcttctat taatcaagtt
    82501 attaagttta atactaaaag ctgctcttac aaatctctca taaaccaatg catccataca
    82561 taaatcctcc attatcacaa taatatattt acattatatt acaataatag agttatcaca
    82621 acaaacaacc acttctagtt gataactttt atctatctat taataaaatc caatgcttta
    82681 taaagtgtat caaatctatc attacctttt atcatagtaa atttttcttt agtaatagaa
    82741 cttatctttt cacatgcgcc acctcctaca acatataaat tttccgtctg acctggtacg
    82801 taatctttta tatcacaaac taaaactttg cttggactat agccccaact aagcacattc
    82861 gcaagtatct tatcaacttc tccatcataa acaattgtat gtttgtacat ctgtttaact
    82921 ccctcattat ttatattttt atttaaaata ccttctgcta ttaacttagc aactatgtct
    82981 ttatgtctaa tataataatc tgtatctgct ttgctatcta cgaagcacac ttctattaat
    83041 atcgctggag cttttgtatg actaagccag taaagccctc tgacatctga ttttgcacct
    83101 ctgtttttaa atacagttgc taatttagta tttaccctat ctgcgtatat tttcccgtta
    83161 ttagttttgt aaattgtctc tgtacccata gaatttaatg ttgtatggtc agcgttaaaa
    83221 tgtatttgta cagctacatc tacattttgc ctattggcaa tttcacattg ttctgctaaa
    83281 tagttattag acttatctac ttttccagta tatacagtag ctccaccttg tttcaaccat
    83341 tttactatta aatcagttag gattctgttt tcttttcctt catctatata cccagttgct
    83401 cctgttcctt ttccacttaa agtgtgtcct ggtactattg ctattttcat tatttatcac
    83461 catccttcaa ctgtttgtaa acttgatttg cccctattgc aactccccaa cataaaattc
    83521 cttgtaaaat tgatgaagga ttaaatccta acatccatat tgaaaatcca attcctatca
    83581 caagcaatat gattggaatg tatttattat ctaactgttt gtatttctta aatccaaatc
    83641 ctaatacatt aagagcaact actaataaaa gcagttgctc tggtataaaa cttattaaac
    83701 tatccatacc ttaacctcct aattaattaa aatattcctc tttgaactgc aaatataaag
    83761 aatcctacaa gtgttgtaat cattgtacca attagccact tcaacatact tgtaagtgag
    83821 tttagattct cacacaatgc ttttaactct gctttagact ctatattcgc tatctttaat
    83881 tcgtctattt catcactgtg tctgtttatt cttatttcat ttcgttttat tttttctttt
    83941 ataacttctt cattcatgta agcctcctaa tttttgatat taaaaaagaa cctattttgc
    84001 aggttctgct ccttctacca ctccactatg ctctataata taatcctcta ctgcttttct
    84061 gtactctgtg ttagttacat catctaactc aaaaggtctg tttttcaaag ggtttaaccc
    84121 tccatttaat attctttctg ctaatattct taccacaaca ttatttatat tcattataaa
    84181 attcctcctc cgatttcttg atttgtcaat aaaagtaatt gattttctaa ctcttgtttt
    84241 tctttttctg cttcacttac atatactggt atttcttcca aaattggctg ttttgtttct
    84301 atatttatac ctacaattct atttttaata taatctatac ttccatatgg aatatcaata
    84361 taatgtaatt cagttatttt attgtgtggt aacacatccc cacaggactc acctgtttca
    84421 aaaattattt tacctgtttg gtcatatatt actctatttg gaacattcat gtttcttctc
    84481 cttcttaaat aaatttaata gcataccatt tataaatatg tctttgagtt gagtcaaagc
    84541 tataagctgg aatttgaaca ccagtattat taaaataaac atctccttcg gaattattat
    84601 agagccagcc attagcatga aaatactcat cactactttt tctaacaaaa gatgtaacac
    84661 ttgaaaaatc aacacctctt tgtgtagcaa caccacaaca agcgaaaagg aaaagtttat
    84721 aattattttt atattcagta tcatagtaat caaaatcagc aaagaaaata ttaggcttaa
    84781 aatctaagtt actaatttta acccaagcgc taggtttaaa aactctatca gttagatatg
    84841 gataagcaat tttagtgtca tcacccttaa aaggagtaac tgtgccactt gcgactttat
    84901 attttgtatt taactgtgtt atggtattat tagcttgtgt tagctgattc atcaaatcct
    84961 gcacactagc gtcagaactg tcaaaacttg tttttatttt ctctgataac tccactagcg
    85021 tgttattcaa acttgcttct atattcttta atgctaaagt atttataata cttgttttgc
    85081 cgcttttgaa tgtatcttta atctctatcc atttgtttgt aacttcatct gttgtagaac
    85141 cagcaggaag aggtgcaatt cctttgctta tacttacaac tttttctgct gtagcattag
    85201 cactgtctgt aacaactatt ttaagtgtgt gtagtgcgtt atcttctaat gtatagttaa
    85261 ttattttctc tgttgttaaa tctgttgtta tagtttcttt tagtacatca tctataaaat
    85321 attctatttt tgtaagcaat gtagggtttg tgtggtcggc tttgaatgtt gctgtagttg
    85381 agttataaga ggatacggtt aaaaaaggta atgcttggag taatgttatt ttagcataac
    85441 catcttgttt cgtagtattt ccacctacaa cgctatttat atcgctaaaa taatatttag
    85501 aagatggact ataatttact ggcttataac tattttttgt tagaatatat ccacttccac
    85561 caccaccaaa ttcagcataa aaactacctg caccacaata ccaaccacca ccgccaccaa
    85621 caccactaat gccatctcca gcaccactta caccaaaaga accattataa agactattaa
    85681 aagttaaacc accttgaaat tgacttccac cgcctgcaaa atatttattt gctatagaaa
    85741 taccatcttt accttttgta ccaccgccat gaccaatact atcatgtgaa tttccgcttc
    85801 caccaccacc gccacctgca acaattatac gagatagcaa actttgtaaa ttatcccagt
    85861 taccatcaat aagtctaata tcagtagctc caccacctgc aagactataa taaccatcag
    85921 aagtactttt ataagtgttt ataccacccg caccattaaa accacttcta caagtctcaa
    85981 taccattaac acctttacaa taaccacttt gcccaacgta aacatgtaat gtagtatttt
    86041 ctttcaatat taaagaacca gcagtatagc caccttttgc acactgtaca aaatcataat
    86101 aattaccacc acaagcacca aaacattcaa acttatattt accaggtggc aacactacac
    86161 tttgttcagc acctgtataa ttaaattcat aaactatagc catttttcac tctcctatct
    86221 taaataggta acatatcatt ttgtatagat atattaacct cattaaaatt ttctattttt
    86281 ctaacaactt catcaatcgc cccttgcaca ttcgtagcaa taagattact tgttgcatta
    86341 ttatagcttg ttttctctgc tgttgtttct atactatcta cactagcttt tacctcattt
    86401 aaggcactaa ctatatttgt tttatctatt gtagtaagtt gtgttgtatc tcctatttta
    86461 tcccctaatt cttttttagc atcatctatt ttcttatttg ttgctgtatt attatcagtt
    86521 atctttttat ctaaattagt tatacttgtt tttatttttt cttcatcttt tttagttaaa
    86581 aatattgcag ttgggtcaac aactaatgtc actttctcca cattagatac ttctatgata
    86641 aatttcaagt ataagtcttt catggctcca ttgccaactt ttggcttgta agtttcgggg
    86701 cttttgcaaa ttgcaatcat atctccttca ttatctataa gacccatttc tctaactgta
    86761 aatccgccta tcgaaccagg gatacatgct gttgcaataa tccagttagg attattctca
    86821 tcattatcaa aagcgtttat attaccttcc caaactttat tttttaaagc tgcttggtct
    86881 tctgttggat tataataatt tcctccacca tctcctgctt gaatcttctc taaaactact
    86941 ggcttaccta acattcctgc attagcaatc ttagctttac ctatatttgt tagtatcgtg
    87001 taaaattgtt catcagccat ttataccacc tcctatcttg gatacactgt taatgtttct
    87061 gaactcatgt tatgagctag tgcaaacttg gctttaacac ttgcttttac ttctttgctt
    87121 gtataaggat atactgttat ttcttcactc ataattgttg tttgtgcaaa ataagttcta
    87181 ctttttaata gagatactaa cttatagctt acagataaat gagaaggttt tataacattt
    87241 actcttttat ataaatcttc taagcttcta ggaaaacctt gagtactggt taattcaaca
    87301 ccaaaagtgt atggagctat gttttcattt atttttatat ctgcacctgt ataagattga
    87361 agtatcatag acatcctttt aggtgtcatg atatatttac tttgaagttt agcaatgact
    87421 tttcttcttc tagtttccat atcttcatct aagttagtaa tcaaccctac tctattttcc
    87481 caaaagccca aaccccacgt tgcagtttga ggaaataatt gtaattctat ttctttattt
    87541 aataattcta gattatcaaa ttcgcttcct atagcttcat atatagagtt cataactaaa
    87601 gattgttcat agataggaga taatgttaga agcatttctt tacctttttt agaagttatc
    87661 atccaaccac ctcgttaact atttccccta ttccgaccac ttggtcttgc aattttatat
    87721 tttcttttgc atcatttata gtaagattag aaaagtcttg tataccttca tctgtcaaca
    87781 tcatagaacc tactatcgct tgtatagcat tgtatgaaac tgttccccct aaatcaatct
    87841 tatctaaata tttatctatc ttagttttta gattgtttaa tactgtttct tcattaaaac
    87901 tgttactaaa tataaaacta gcttttacat taataagtaa tgtgtcaggt gttacaactg
    87961 taactaatgc accgatagga gctttcccat ctctattttc tccttctgat atatttaatg
    88021 gatatatata ttcttgaacc ttgtctatta actcttgtgt tgctgctttt ctatttttat
    88081 ctagtattaa tacttttact gtccccgctc cattccattc gggaactaca taagcatatc
    88141 caactccatc tacttcttta gcccatctta tataatctga actagctcca ctaagtttgt
    88201 cttcttgctc tgctacaagg actctttctc taaaatgttc ttcatcttct atatctgttc
    88261 cacctttgaa atctttatta gtaactgatt taacaccatt aatagaacct agtaaaacgg
    88321 atatactacc tttagacaca ttccctatag ttcctacaat cctactttct gctttaatat
    88381 ctactgtttc attttctcct atagttttgg tttcaagaag ctcaaattct atgctctgtt
    88441 tttcatcagt tgcaatagta gttactatag ttccttttgt aatgatagtt ccttgtacac
    88501 ctgtaaatgt aataactcca gtagccttag ttggttgatt tttaaatact cctttacatt
    88561 caccaagcca ctctaaataa gttccataag aagtctgagg aaatgctatc tttaaattat
    88621 tttgtaatcc tagttgtttt aattcagcta tctgctctgc tgtaggtctt gttgcatcat
    88681 agatgaagtc accttctaat gtagaaacat cttgaaagtt gcttaacatc ctttcatgta
    88741 cagagtcctc atcttctgtt aaaaatactg gtataggtag ctctctttcc atataatcac
    88801 ctaccttttt atattgccat caattactat attttcatca tctattgtta gtacatcaaa
    88861 ttcatactct actaacctgc tattctccaa ccaattaaag ctaaactctc ctacttcttt
    88921 tgtgtaagga tgaaccaaaa tagtttcttt tattaatcta gttatttcaa gctcttttgc
    88981 actttgagat aagttactag ctattaagtc ttttatttca cttccataaa tgtttgtata
    89041 agctgctttt ttgtatctag gtgttaatat agccttttga caccattgtt tgtacgcctg
    89101 caccttatca cattttttta gtgttccatc tgcgttttta acaaattcac ctttttcaaa
    89161 atcaaataaa aaagaaccct ttaggtccaa ttcattttca tcattatttt ttaattctac
    89221 agtttcaaaa gtttcacttt gaggaaatag gtttggcatt tacaaccctc ccaattacta
    89281 caaattcagc tcccataaca gctactagca cattatcgcc tatacgtagt ggcttcaatt
    89341 cctttggagt ttctatttta tgcttatgtc tatattctcc acttaaagct tcatctgaaa
    89401 aagtaaaata atcttctttt aatgttaaat tctctaatac tagatagtcc tgtatttcat
    89461 ctttatagcc atttactttt aatccatttg ctgttatttc tgcaagttca caacccattc
    89521 caaaagtgcc atttgctaca cttttattca tattttcttt caatattcta gcaattccat
    89581 taaatctagc atcagtcatt attataaaat ttcctcctta tatattctaa agaccctata
    89641 ttcagcttca ttttcggtct agaatctagt gtatgagtga catctataac ataatattct
    89701 ttacttttta aacttacttt gtcacctgct cttattctat ttatatctac tgcacaatct
    89761 acacttattg tttcctctcc actattgaac attgcttctg ctgctttctt agcttcttta
    89821 gcatttttta tcttttcatc ttgtttaatc ttttgtagtg ttccaaactt atcagcatct
    89881 tttttatatg tcccaattat aggcgctttt gtattttcgt ctttactctt acctaaaact
    89941 tttacacttg ttactgcatc attaaaacta cttgtaaagt tagcatcttc taatatacta
    90001 tctaatttat atacatttgc attagtacca agcttgaata attttaattt attatccatc
    90061 cttactctaa ataagtctcc accttttgtt gctgtttctt ttaagtcctt ttttatcata
    90121 tctagtatat ttgtcttatg tattacttta gcaagtttct tccctgtatt agctaagttg
    90181 taatagggta tattccattg cttacagtaa tattcaattc tctgtgttgc tgtattttct
    90241 ttaaactgat attgttcctc tgattcttcc atgtaaactg ttctttctct gcaagacaat
    90301 gttagtttct tactcttttc actccttcta gtttcccata caactccatc aaatattgtc
    90361 tcttcttttt tactctcata tgctatatca attagaatta ttttatcacc ttttttaata
    90421 tttatatctt taagttgttt aggttctact aatgatacat ccatcttata tgcaactccg
    90481 tctatagctt ctgaaagagt tattccttca ttgaaatttg caatatcata tttcccgttt
    90541 aatattattt tcatttacta ggtatcacca acttttgacc ttttttaatt atattaggat
    90601 ttttaccaat gacttttttg ttttcgggta tattataaat ctctggccac cttgaaccct
    90661 tacctaaaag atttttagct atcttatata atgtatcact tgctttaaca gtatatattt
    90721 tagatttagt ttgggtatta ggtctattat cttttaaatc tgttttagta ttactttttg
    90781 tatctttttt taatgtctct atcttcagtt ctctgtaagt tctaaatgtt atctcaatgt
    90841 ctctatcttc ttctcttcct gctgtttgag tattgctaaa actagatatt gtgactaatc
    90901 cattgtagcc aaaaccagtt ataataagtc ttaaaggttc ggcttggtct acccattttt
    90961 caagcattgc cactacttcg attggatttt ttaactcgct gtatctgcaa taagaagcgt
    91021 catataagtt aggcagaaat gttttaaatg atatttctct tatcttctcc ccttcttttt
    91081 ttatatcaaa ttcacctaag tttactatat ctacagtttc aaaccttttt tcttttttta
    91141 tagataaaga atcttgtgga tttactggaa aatgaaaatc tattttttct ttttcatttt
    91201 ttagataaat atctattacc aagttatcac ctctttttta caataaaaag ctcctacaaa
    91261 ctgtaagagc tttaaagtat tatacaaata ttaattaaac ataaaattta tttgttcttc
    91321 tatgctatta acttccttat ttgtattatt aatatgattc tgaaattttg gtggttgtgt
    91381 atggaaacca tcacttattg caacagattt gtcgggttca tcttttttat tgtattgcat
    91441 aactgttaca acttcttctc cagtatcatt ttcataaaat tgaaattgaa tggtatcatt
    91501 actttggtta tcatatacat taatctgtct taatgtagtt tcattcggct ctataacttc
    91561 atatttataa ccgaatatat ctaggtttga ctttatacct tcataagatg tcatattaac
    91621 acaattttta ttttttaaat atacatcagt aaaaaacttt gttggttcat tgttttgctc
    91681 tttttcttca ttcttttttt gttcttccaa tttttttgat tcttctttct tttgttgttg
    91741 ttcttgaata ttattctcgg attttccctt atctttatca ttataagaaa cttgcttcac
    91801 aggaatatgc tcttctttct ctatacttag tacattataa acatttctag tacaaagtgt
    91861 tgtcaaaaaa actaatatgc aacctaatgc aattttagct tttttcttac ttccaatagc
    91921 tttaactaaa aactcaatag ataacaaaac caatgttatt ggtaaaagaa ttatagctat
    91981 aattccaata ataattttta aaattccatt catactttta aatttctgcc acataaaatt
    92041 tccccctcat aaatttgcat attttaacaa tattatatca tttatgagga agattttttt
    92101 agcaacaatt cgacattatc caatatcttg taatgcttct cttattccac tttctacttg
    92161 agataatagt tcttgtatca tttcttcttt gttatcacta ttttgaacat ttatagatat
    92221 tccgcctaaa tttatagtat tattagaaga attaacactg tttggtgtag cttctttata
    92281 ttctttatta tctgtatcta aaacatttgc aagaggaaat tgtctaacat tatttacaat
    92341 attagaatta cctacttttt gagaaggagt tgaacctaat cctaacattt tacctgtttg
    92401 ttcatataat tctattgctc tacttcttct agtgtttgta agagggataa ccatttcagc
    92461 tccattctct ccgcagatag aagttcttgt tgctactcca ccatcagcaa aacggtctag
    92521 tatattaccc agtattccac cactactttc atttacggtt cttttaactg ttgtttgagt
    92581 agtcttaaca ttaaaagatg ctgtaattgg tgctgaaact gttgctctta cactattcca
    92641 atagctgata atttgactcg acatggcact aacttggctt actacagaac tacacatagc
    92701 agaaatggca cttatagctg aactgcttaa actcgtaaaa gatgttctag ctccattgta
    92761 catgctacta catgcaactc taacatttgt tgctaacata ttaaaagaag ttgtagcacc
    92821 attataaaga cttgaacctg cttctctacc tatttgtgct agttgtgtaa aactttgttt
    92881 agcaccatta tacatactac tcgccccttg ctgaactgtt gcagtagctt gattgaatgc
    92941 tgtatctata ccacttgtaa gatttgaatt atctatttga ggagttgcac tatttacagc
    93001 atttgttact ccgttttgtg ttgctgtagc aagttcatta cttttttgct gtacaactgg
    93061 cactcctgcc tgtactccat ttactacacc attagtcaaa tctgtaccta attgttgtcc
    93121 tgcttgttgt acagctggat taccttgagt tagagcatta gccacttctt gattcgcttg
    93181 ttgtgccgtt tgagaagctg aaccttgtat ttgacttgaa gcttgagcaa atatacttct
    93241 tacagtttct aaagcttttg gtccttctat tcctagatta ttcaaatttt caagaacttt
    93301 actagcttgt gtttctattg gagtactaaa gtctacatta gcaaatactt gccccatctt
    93361 tccatccatt ttgcctaatg cttgttgcat ttgtggacct gcttggttaa tagttccaag
    93421 catactattt atagcgtttt ttattcctcc actattaaat ccttctttaa aagagttaaa
    93481 tgtattgctt aaaccttgct ttaaatttgt agtatccaaa gcagatgatg cttgtgagaa
    93541 aatagttctt aaagtatcta tagcctgtgt tccttctaat cctaaactat ttaaattctg
    93601 taatacttta gttttctgtg catctataga agaattaaaa tccactcctt tgaaaatctc
    93661 acttgctttt cctcctaaac cttttaaggt ttctaaagct tgtggaccag ttgcttttaa
    93721 agagttcaac attcctgtta ctccgtcttt taatccgcct atatttgtcc cttccttgaa
    93781 ggcattgaaa gcatcactca taccttgttt caaattattt gaagaatctg cactatactt
    93841 gcttataaaa tttaaagtct cttgtatgct acttctgtat tcttgtgcac ttaatttacc
    93901 tgctttgaaa gcatcatcaa gatttttggt gattttatta actttgtcac taggtttcat
    93961 atctgctgtc acaccagata aaattatcgc catattgtca ttcaaacctc tcatcatagt
    94021 aagagattgg tcatctaaac cctttaatcc atttgttaat gctctagcta tatcgctaga
    94081 tttcttctct gttacatttt tagattggtc aaatgctgtt gagaaagctt tagtaacacc
    94141 ttgtaactct tttgaagtag acttttttaa tagagctgtt gcattagaag tttctccatt
    94201 tatatctgat aaagcttctt ttgtatttgt tttaatttct gctgttgttt tgccaaatag
    94261 atttttaagt gatgaagctt tttcatccca gctcttatca gataaaagta ttcctattcc
    94321 ttttccaatt ccacctaaca ttataagcaa gttacctaac gtaagcttta tgactccacc
    94381 aacagtctcc attattgtag taacatactc accaaacgaa ccaaaacgtg tttgtaagtc
    94441 catcatagca gttttattat tagaaatagc aacagtcatt cctgcaaaag ctataacaat
    94501 agcccctatt ccaactgtta atccgaaggc aactaattta gccgtaccaa aagtacttgc
    94561 aagtaaactt aaacttttaa tggctcctcc aaaagcaaat gtggctttaa gtaccataac
    94621 agaggctata acggaaccaa ttgcaggcaa taatacttga aatcctgctt ttattttatc
    94681 gaaattatta acaaactttt ctactactcc aactatagca tcaccgattt gtggcatttt
    94741 cttaattaaa tcttctacaa atcctcttgt cataggtcct agtctttgac ctacacttat
    94801 ccttacatca tcaatagcac tttttaaaat ttcaaattgt cctgataagg tatctaactt
    94861 catattagca attctcttag cttctccttc actttctgca atagctgtag ttaacttatt
    94921 aaagtcactt tcactagcat ttactacagc cgcccaacct gccattgcag tacgaccaaa
    94981 tatagaggat attgcaacac ctttttcaac atcttttaat cctcctaatt tctctctaag
    95041 acttcctatt gttcctgcca agtctaaact tccattttta tttttcttta attctattcc
    95101 atatttttta attgcagatg cggcttcttc tggtggcttt attaatctaa ctagacctcc
    95161 tcttaacgaa gtacctgcca tacttccctt gacacttgca ctagccatta gacctgtcgc
    95221 aagagataaa tctttcatag atactcctaa tgctccgccc atagagccta cgtatttaaa
    95281 tgtttcaccc attaactcaa cacttgtatt tgaattagtt attgttgctg ccatcacatc
    95341 aacaaattca gttgtgtcat ttgcagtcat tcctaatgca gttagtccat cagtcacaat
    95401 gtcactcgtt aacgctaagt ctgttcctcc tgctgctgcc aagttaagaa cgtcaggaat
    95461 tgcttttatc atttgctcgg acttccatcc tgccataccc atgtaataca ttgcgtctcc
    95521 tgcatcttta gctgtaaaac tagtttctct cccaagctgt ctagcttttg cagttaaagc
    95581 ttccatttct tttcctgttg ctccacttac ggcttgtgta ttcttcatac tttgttcaaa
    95641 agtagcaaat ccttttacag cagaacctac accaattcca cctattaaag ctcctgcggt
    95701 agtagccagt ctagcgaatt tactaatagc tccacttaca aaagaatcta tttttcctgt
    95761 aagccctcta agtgctgaac tagcttcatc tctaatctta actgctgctt catatctctt
    95821 actcacaaat tcttgtaatt tatttttagt tcgagaaata gtatttatag cttcatcagc
    95881 ttgtgatttt atttttatga tagtatcagc ttttagattc tgaatcttag cttttacttt
    95941 atctattata gaactagatt catcttgtcc tcgtatgatt acaggaggta caggcttagc
    96001 aacttctttt atcttattat taactttgtt aacagtagaa ctcgcattat ctgtagcttt
    96061 caaccttgct gttactgtct ttttagcttt attaacatta ttgctagctc tattggctac
    96121 tggactcgcg ttatctgtag cttttattct agctgtaaca gttttttttg ctttattcat
    96181 attgttatta actctattta caacacttga agctttatca gtagctttta tagcaggatt
    96241 aacctttatc ctattaagtg tttgcatcct tttttctgtc tgcttcatgt atttttccat
    96301 agcacttagt ttgctttttg tttctccgtc gccttttgca cttatgacaa catcaatatg
    96361 atacatttcc tttttagcta tttccctcac ctacctttct gtagatattt attttttcat
    96421 agctttattc tcttgctcta tttcattttg agtaaatact ttcattaagc gttgagacat
    96481 taaatttttc ttaacataaa catctggggg aacatgatgc ttgacaaaga tgttatttaa
    96541 aacagtcagt cgtcccccca tttttattag ttttttatat catcatcact tatttcatca
    96601 taaaaaccgg ataattctaa tatttggtca cttattttac ttaattctcc agctaagaat
    96661 tttctcttta taaattctct agcatttgtt actttcatag cattaagtaa tttttgatta
    96721 gaaaaattag gttttacagt tcctttttct attaatgcta gagtaaactc atcatcattt
    96781 aatttttctt ctcttcgccc ttggaccttt acaattttag tgcattcttt tcttatttta
    96841 ctaatctctt tttctgttaa tgctttcaaa gtaattggta ttcctaatct atctaaaaac
    96901 acagttctct gaggaactgg tgaatcctcc aatagctttg ctattatttc atcctctttc
    96961 atcttcaatc tatcttcatt tgtttcttct atttcttcat ctaaatcatt atcttctact
    97021 acttcatttt ctaactctct tttatatatc tctgacatac tattcctcca atatttttaa
    97081 ttttaaaaag ctacaaacaa aattaattgt tcatagcttt aaagtacaac attattttgt
    97141 tttaaagttc atttaacaaa tcatatcctc taaaacttcc ctctacttct atttttacaa
    97201 tttcaccagc tttagaattt ataagaggca atttttttaa tctacaattc tttaatctaa
    97261 tactttcata tcctaatgtt tcagaattag ataaattata tattatttca aaagacctaa
    97321 atcctaattt tgcaaatttt gaatctgtct tatatccatt caaggagaat gaacctttag
    97381 tagtaccaac ccttgatatt tcattttgac accctaacag tttaatactt tgctcatctt
    97441 gctcaaaatc agcttttatt tcttccatgt atagctcttc tacaccatca ataagtataa
    97501 ctacatcaga accattcaga aaactggctt cttctatata atcatcatta tacataatct
    97561 ataacctcct ttatcctaag tatccagtac catatatttt tttcatgaca tcaaccttaa
    97621 cagcatccca cttccagtaa aattcatctg ctttggcagt tgcttgaagc tctgtatcta
    97681 tatcaacatt aaattctgat ataatacctt gactcatcaa ttcttcaaaa tatttcttca
    97741 atgcacatat aacagttgtt tgacctgttg catcattaaa tatcttacct acaaactctt
    97801 ttctttttaa tgaagtatct ttatttatag tattaataaa catgatatta gagatatatc
    97861 ccattgcttc gtttttatca tctacatatt ttttaaatgt gttcacatca tcaactataa
    97921 tcacatctcc atcatcaaaa tctaagacca atgtaccact tttcaaacac tctttaactt
    97981 ctgattgact taatcgtggt tctacttctt caaatatagt ttttgcatta catatactac
    98041 ccgttatacc tttacttaca gaaagagcag caatgtaaac agctacttca ctaggtgtat
    98101 attttatatt ttcataataa gctgagcttc caacgttaac tatattttca tcattgaaac
    98161 tttttgattt atcatttatc tgttttatat tatcctctgt ttttccacct agaaaaagta
    98221 gtatatcttt tcctaattct ttatttttag ctacccaagc ttttgtagtt tcctgcaatg
    98281 cttcatcagc cacaccatca agtacaaaag agtcaaaact atatctttca aattcttcta
    98341 gtgcttttag ataagactca ttagtaatag atgtgcaacc atcattccca ccctctaaag
    98401 cttgatttac tacatttgct agaattgtat cgctatcagc tactttagtt gcaattacat
    98461 actcattatc taaatttgag tttatttcta gtactatttc atctatagtg cctttaatac
    98521 ttgaactaaa taactgttta gtattttcaa agaatataaa gtccttttta tctgaatcta
    98581 ctaaattgga ttttattgtt acattaaagt ttctagctgt tggatactta gtttctaact
    98641 taattacatc ttttgcacta ttttctgtag tatcttttag tgttaatgta cccttctttt
    98701 gttttccatc tacaagccta tataataaca gctcttttac atttcctaat aaagctaatt
    98761 tacctaactt atacgctgaa tagttcatat catcaccaaa caaagtttta agctgtctca
    98821 agtcattttt tattgttaca accttgccaa cttctcccca attagcctta actggtattg
    98881 ctaatctacc ctttaatcct gtgtttgcag acttttctgc ttgtgttttg aatctgttat
    98941 aaaagcccgg tatctccttt ttttcttttt cattccatgt accagttgcc attttacttc
    99001 acctctcttt ctaaaaaatc ttttattaat ttctcaaact ctgattttgt aagttcttct
    99061 ttcttacaat taaataaagc acctgcaact accatttttt cgtagccaag tgcttcacta
    99121 ttttttaaga aatcattttt caaatatttt tcttcctgct tacttacatt agtcttttta
    99181 ttaattgttt cagccaaccc ttacacctcc tattttaaat ttccattact ataaatttta
    99241 tccataatag gaccttctct ttttatctta cctatcattt tgaacacaac tgttaattgt
    99301 cctgttgtaa acatgtctga ttccctatcc tcaactacgc taacaagagt taaatacata
    99361 ttcttatcct ctctaagtct tactctttta tctattatta aacttgtttc taatgcttca
    99421 agaaacttaa ctatttcatc cttattttta cttacaacat gacatttcat agttttggta
    99481 atctcaatca aatgataatt tattcttttg ttttcaacat ttgtagttcg ccataatgcg
    99541 catggagcta taaagttttt cttccaatta tctttataac tctcaatttc taataaatct
    99601 tttgtgtact ttgataaagc ttctacccat ctatcgctag ttgcatcttc tttatcttct
    99661 aaagctatta cactaaacct tatacctctt gctatagcat cccattcctc aacaacaata
    99721 tcattttcac ttgtcccttt ataaatgcaa gtgaaagctt cattttcaga ttcatcaact
    99781 atagtattca tgtctaagat ttcaataact tgtttagtta atttatctaa cttcttaaat
    99841 gtagttctac cttcataaat ccatacttct atacttcttt caaaacctat cgtttctcca
    99901 ttgtcattgt cttgcccttg tacaactacc atataaggct ttttagtatc tttgtttggt
    99961 acattaggtt cataacaacc tttcaattct tttatattat ctattaaagc ttttcttatt
   100021 cctgccctca tttaatcact ccaatatcta aaaatcatat tacctatttt gcctatattt
   100081 ttatcaatag ttggttttat aataggcatt gcttttgtac caggatgttg aactgatttt
   100141 acaggatgtg aagcacctct ccagtataaa gcttgagctg attttggagt aataacatgt
   100201 ggttttgaac cttcttcaag tattcctcca tattctgcac catgcgataa tctaataatg
   100261 aaattatttc ctcctccaag agttttagca tttaaacttt gtcttgcatg tgatgttctg
   100321 tctgtccaac ttgcatttgc tttagcttca ccttctagca ttgcacttgc actcatacaa
   100381 agtacaaaca tacctgcttt ttttctattt atatcattta ttgcatttgt gaaagcactc
   100441 attttaatca atcctttcaa gtgaacattg atacccacaa agttctcctt ttacaatttg
   100501 aggatataca ttaactattt tcattctccc atatatgcac tcaaactcca aagaatctct
   100561 actgttaaca tctaagacaa catcatcact tactaacatt ccatatgttc taatagaact
   100621 aaaagtacct tgcttttcac ttgatatttg tttctctgct gtcttttcat taaatattct
   100681 aacaacacat tttatctctg tttcagtttc ttcaaaagct ccatctattt cagttttttt
   100741 aatattagtt atagtaatat tggtagggtt catattaata gttcttatta tgtcttttct
   100801 tcttctatca atatttatca tatttcaaat tctgtgctaa ttcctaacat aaaacttccc
   100861 ttttcttttt tgttagtaca catatccttg aatttctctg cattttgata agctacagat
   100921 actaggtcct ttatactaga gcttttatat gtttcttgac ccactttata ctcatacatt
   100981 tcccctactg tattttcata ttgtaaagat tttaataccc atccttgaga agctgcacag
   101041 taaatacagt ctgcttcttc taaaaacaag tttaattctt catctgtaaa tgatttttta
   101101 tctttatcat ttaataatag tcttaatttt tctattaaat tactagttgg tgtcatatat
   101161 tatcacctca taaaaataac actcttatga gtgttttatc taaaacttat ttcttgtaca
   101221 ttttcttcta ctgctgcaaa agcacctcta taacaatgac ctacaatttg attttctact
   101281 aacttactta aatcagcatt tccaacctct gttgttaaat ctctctttat taactcttta
   101341 aatcctcgct taggtcttat caaatatcct ttgcctggtg taacaccttt gtaagaatat
   101401 gtttttttac caacagtaac ctcccaccca tcataataaa ttactgttga tatatttttt
   101461 atagatggat acatgcttcc gtttaataaa tgtcctccat ttaacgccat ttctatttca
   101521 atttggtcag cactagaagc cattaatata ttaccttgtc tttttgctat aactgtatct
   101581 ttttgtgctt gtgttaatgt tctccaaatt cctagccata ttgggtcatt agtttcacct
   101641 ttaaaagctg tcttattaga agctttataa ttaaaattta ttattgggct tagatgtatg
   101701 tggtttaaca aggcattgta actctcacca attgatttat ttaatatttc aacactaaat
   101761 gtttggttaa aatccttcat ttcttttgta tactcaaaac cagttgcata agtttgtatc
   101821 cttgcaactg gaccattttc tgcatttatt gtaccgaatt taatttcttc accttctata
   101881 tgctctagga atacacagtt accttgtaaa gcccacttag catccataac ttgtggtaaa
   101941 ttagaatctg ctatactgtc atagattggt ttatataata gttgtacttg ctctctgcct
   102001 agttcaacat ctaatacaac ttttcttaat aactctttta aatttgaagt cgagctaaaa
   102061 gtcatcattt caccaagtgg cttatttaac tccaaggttt ccatttctcc atttgatatt
   102121 ttctttgtta catattccat ttcaccattt actataaatg gtatatcttc ttgtaaagtt
   102181 tcttttcttt tttgttccag caaattttcc tgactaatta ctttaaatgc catatattta
   102241 tcactccttt tctattgttg aggtaataat ataaaccaaa ttacattatt actgtctttc
   102301 ccatctgtta ctctaccaac tagcctatta cttgcagatg tagtagtaaa tttcttagct
   102361 gtattatccc aataaatcaa tttccctgcc tcaaaagctt ctgatgtaac aatattatcc
   102421 gtttcgtatt cagcttgctc tatttgcaaa gtaacttcat cgcctttttc tccgtcttgc
   102481 atagcgactc caaagaatcc atttataaga taaaattgtt gtgttttagt gctttcacct
   102541 tctgaaagaa taactcttac agatttccca tcacttattt ttgctcttgt tatctgtgtt
   102601 attgtgcttg gcgttggttg acctttaaat gccatataaa catcactcct ttatattcta
   102661 tttttcttag ttgttaaact tccattattg ctagagttta ataatcctgt tgttgttgga
   102721 ttatctttat acatattaga cattgtattt tttacaaact catcatttaa tatattttct
   102781 atttctcctg ttattacttc ttcacttgag ccttcctcaa catttaacat tttcttaact
   102841 aatgtttgag ctatttcacc tgacacttta tctttaatta ctttattaac tatacagttc
   102901 caagcttcct ttttctcatt ttctaaagct tttgaagcct tttttgccac ttcaactgtg
   102961 tccatctctc ctactattcc aagtactttt ttcacttctc ttaattcttt ttctgctttt
   103021 aatgaacttt ttacatcttc catctctcct gtcacaattt ccttagttaa gcctattcct
   103081 tgtatgacct ctgaatatga tatttcacca gtttgcagta atcctttgac attttttatt
   103141 aactcttttc cttccaattt gttttcctct cctttcattt ctcctttagc ttcatagctt
   103201 attttcttta ttacttcaat ttcttcacct agatttattt tattttcaac tatagtaaat
   103261 ggtatactat aaagcttgca taatccattt tgctccaact catatatgac agtattgtta
   103321 tcatatctta tgttttgtat atagagatat gaattattat cattaataga aaacttagct
   103381 tttaaagctt ctcttaaatc tattcttaaa gcttcaaaag ttccatctaa ctgttcgcca
   103441 ttaggactca tttccatacc tacaatactt gttggcatac ctggtctatg tagaggagtc
   103501 caatcaatag atagtggctc atatcctata acattcattt cgcctttagc actcttttta
   103561 agttttggat aaccaaatat actaacttct tttatccttt tagttctaat ccatcttttt
   103621 aaatttgttg catcagcatc aatcagccct ctgaaataag ctttatcccc tttcatttct
   103681 gcacctatcc aatgcgttac aggtagtgca aattcagttg atatattttc agctttttga
   103741 tgtcctaaaa agccattaag agtattttca ttagtgtaat ctacaatatc tttcaagctt
   103801 ttagcagtat aattccatcc ccttttagat tttgtagctg gtatctcaac aactacctca
   103861 agagggtcat catctataga ttttaaagct tctatgtcta tatctttagc taaaggaata
   103921 tcagaaggtt ttatactaga tattaacgca ttcattgagt ccatttctcc agttattaca
   103981 ttcatttaat caccaccttt caatttaaaa attcaaattt ccatacacct cttgatacca
   104041 catttcaaga ggtacatcat tcataggatt tttaatccaa tttttcaacc ttccaactaa
   104101 tatatctaat ggttgaacta cagtaagcat aatacacaaa caatgagggt ggaatggata
   104161 tacaggagct tcatttatag gataaacacc tttacccaaa ccaaaattat cctctccaca
   104221 tatttcgtca catatatctg tgtgaggatg tgccatggac aacataaact gaatacctat
   104281 ggttgcaggg ttaatcattg cagaagctaa aaccccatca ccataagctg atgtcatttc
   104341 agttcttgcc aatcttaaag cttcataact tatattttga ggtactctat ttcctattct
   104401 ttttatcata tttggatatt catcaactaa agttttctta ccttttaaaa catatttgtc
   104461 taacatctta gctgttttaa cacagtcttg accttctgtt actgctgttt gtaatataac
   104521 tttcatatct tctctgtact tcttacactt agaccaaatt ctatcagata aaaataaacc
   104581 atccttaacc cttgtataat aagcttctac agttcttata ttaatatcat agaaagcttt
   104641 ttgtatcata gttttagtta ctttagttat ttgagctgtc tcaactgcat taattaaaat
   104701 atttttagag taactagtag ctgtttcaac atttttattt aagtattcat caaaattaaa
   104761 tactagttgt tcatttaata tttttatttc ttgtgttaat tgttttagta tctgttttaa
   104821 cctaactttg ttaaagtctg aaagatttcc ttttcttatt tcttttgtaa tatttcttgt
   104881 tatgttaata tacattgttc ttatttcatc atcttgcttg agccttaaat ctataaattt
   104941 ttttctagct tctaatgccc atttcttgta ctcccctgca acagttatta attccgaagt
   105001 acttttatcc attgccatta ttatccttta ttttatttat ttccttctca atttcatttg
   105061 actcatcatt taaaccttga gagtcatcta atctgtattt taacatcttg gtttttatta
   105121 tcttttctct ttctccaact atttcagggt catcacttat ataattgctc attgtatcta
   105181 tatactgtgc taaaaagttt actgttgatt cttcactaat aaatccaccc tctaaagctt
   105241 tatctaatgc actacatact ttttctagtg tttcagctaa ttctttatca tctcgtggat
   105301 ttacttcatc ccaacctata gtcacatcat aagatgaata tttcatacca ctagaattag
   105361 aactcattat taaaaccatt cttgcaagta attgccagct atttgtaaat tgttctcttt
   105421 ttcttcttat cttatttacc ataataggca tttgttcttt tacagaagct aaagcactag
   105481 gtgtatgtac tccaaatata aactcgggtg tttcagatac atctactatg caataaaaaa
   105541 gaagctttaa aagctcctta gcatcaccta tggctgattt tacttctaca aactcagctt
   105601 cttcatcttt gtttaagaat agtatttcat gcccatcaag atttatcttt ccaccttctt
   105661 tggcaaattt aactgggtct tcaacaccaa aattgtgtgc taaaaaactt gcaacatcag
   105721 ttaatttcaa ctttagtttt ggagtagagt gcattttgct accttttaac gcatgtaaca
   105781 taacatcatg ataagctttt aaaagaggtt ctattggttc tatatcactt tgcccatatt
   105841 tcaatgtttc atcagcttca tttttaaaat gtattattgg tataaaaccc catacattag
   105901 gcgtttcccc ttcttctaaa ccttctatct tatcaccttc aacctcaaca aatctacttt
   105961 cagcagttat tatttgtttt accttagcct ttctcttgtt ttctcctaag tcagtccatt
   106021 cattttgact ttctaatata taagctatag gctcttttgt tgtagggtct aatattattt
   106081 ctttcacttc ttcgggtgat atgaagttat atattaatct aactttttta tcgggatata
   106141 aaggattttc tctttcttct ctagttatcc aaatataaca atcaccttgc tttaaactat
   106201 ctgtatgtgt ttttaacatt ttagatgtgt tatctaaaac aaattcatct aatatatatt
   106261 gagcttcttc atcttctatt tgaaaatgag gtacacccat aaaaccagtt gttgaattga
   106321 caatcggtct aacaaaacta gaacctagct tgtacttagc atttttattt tgatacagtt
   106381 ctcttgctaa ctcataatca actctagaat cgtctaattt atatacgcca atgtttccac
   106441 tagacatacg cataatctct cctgcaggtc ttttaaatag cttttttaca taagatatta
   106501 tccccataca ctaccccctt tcagtaaaga taaatcagta ttgttatttt ctgcaaacga
   106561 atatattact gcatcagctc tatcgggtga ttctccaatt ctttttttca tttccttttt
   106621 actttctatt tgtattttcc cttttgaatc tactgtatat tttctatttg atagttgttt
   106681 aataagttta tcatcattag gaagctgtat tatagcttct ttattttgta taaaactact
   106741 taaatttgca tctaattcct ccctcatgtt atcccacatt tcagaagctt tattatagta
   106801 cttatctttt tctatagcac tagaaccatt ttgaataggt ataacttcat atttaagtct
   106861 ttcatgtctt ataacttctt ttaatctatc tgttacacct gcacctaagc catcatcatc
   106921 cgtttttatt tttactctgt taatttgatg atacatattt ttaaatttat caactgctct
   106981 taatatattt cctactgttt ccattgtatc tttttttgaa taagttaata aatcaaatac
   107041 tttcccacct attcttggag ctattatggt ttcatcatca ccatatcttg ctatatccgc
   107101 ccctatattt aatatatagt cattagatat attcacttct cttattgtgc ttgtttcaac
   107161 agcttctaaa gatattaaag aatcactttc accttttgga aactctccaa gtactctgac
   107221 acgccaaggg tcagaacctt catggtactt tctttttagc atttcaatat tatcttttga
   107281 tgttctaggg ctgtctaaag aagatacttt aaatgtttta tataaatctc tgtctctatt
   107341 atggctatcg taaaacgttc cactcgttct agttgggttt ccgcataaaa gaagcttatt
   107401 ttctgcacct gataatgttc ccaatatagc ttccataatg gggtcagcaa ctcccgaagc
   107461 ttcatcaaca acaaataaca tataatcttc atgaaaacct tgcatattct cgggctttac
   107521 tgctgttcta gctgtagccc accatctttc ttcaaagcct ttcatataca cttttgtttt
   107581 agtccactca agtagcttct caaccttgct attacttagc catttagcta tttcagccca
   107641 tagtacgtca tataattgtt gtcgtgttgg agctgtagca actactttcg gaaaaggtct
   107701 agtgcttaaa taccatacag ttgcaatgct ttctaatcca gttttaccta ctccttgacc
   107761 acttctaata gatacttttg gggtttgagc taaagccatc agaacatcag attgccactt
   107821 gtcagcttta aaatttaaca tatcctctgc aaaccaaaca ggattatccc aataacaatc
   107881 taatagtgtc aataaagctt tatccattgt taacaccacg tttcattgca atattttgta
   107941 tagcttcaac ccaaattttt gaatcatctc cagtatcact tttctttagg ttatcaactt
   108001 cacattttaa cttttcaact ctatttttct gctcctctgt agccaaattc caatccttat
   108061 gaatcatttc atcatactgt ttaattaaac ttctaagttc actcatagct ctactctgtg
   108121 cattaagaaa agatgcttgc ctatcccatg caaattgaaa ttcatactct atcttctctc
   108181 cattttctgt actttcatgt ttctttaatt ctttaatcat ttcttccttg tctttaacat
   108241 acattatctt ttgtgctctt attattgctg cgtattggat tgttatctgc tcccaaagaa
   108301 tatcaaattt atcttttata gatatttctt gtattaattc cctagtttct tcaggtagat
   108361 attttgagaa gaaaccaaac ttttcagcat ttttatttcc aggaggacca gtggcatttt
   108421 tattacctat gggtgcacct cttttatttt taggtgcacc cttctttttc tcattagccc
   108481 aattgtatct ttttatccat gactttaaag tatttaaact aatgtcatac tttgctgata
   108541 tttccttttg tttcatacct tttaggtaat cttgttttac tttttctttc acatcttgca
   108601 caccaccacc tcgtttgttt gtcgttttgg gaataaaaaa gaactcttgt tagagtctat
   108661 gtatctaatt aaattacatt gatttattgc aaccttttta ttctggaagt ttagataaag
   108721 aattaattat agaaaaagtt caagaacaac taatttcttc aattgaggaa atcaaatcag
   108781 cttattaatt acttctttgc tacaaatttt tttatcaatt tcttttaaac acttattaaa
   108841 agatgttgat atttcttttt ttatgtcttc attagttaaa ttgccaataa ctctattatc
   108901 taaagaaagt tttatatcaa ttgaagtgtc tactccattc atagtagagc tattagaaca
   108961 taagatatca actttagact ggactaaaat atttaatttt ggttcagttt tttctttata
   109021 atcattcata atttattctc cttttaattt attgtataaa aaaaagacct agaaattaat
   109081 ctaagtcttt attttctata ttaactacat aacttgctcc aagcacaact cctcttatta
   109141 ataactcttc atcagctata ccttcattca taaacttttt aatgtgttca actgcatatt
   109201 ctaaaaaatc attatctgct tttatattaa attcatttag ttcttttatt atcttttctc
   109261 ttaaattact catttatcat actcctgtaa aaaaataaaa gactaagctt accctcactt
   109321 agccttttta aatagggaga tacatatatt atgtcgcaag ttctaagaat cgaacttaga
   109381 ttaaacacca gtacctgcat ggtgagtgag gttaccaagc cccacccgat ttttagactt
   109441 ctgaattaag atacaaaata taaaattttg ccctcaattt ctctactttt agtgtatacg
   109501 ttgattaata tttgaacata gttagaattg aactaacagc gtcctcacgc cctgcctagt
   109561 ctgttcgtag tgactagggc aatcccttat accctagtca aatattaagt tttgagaggg
   109621 aaatctttat ttccacaata ctattatctc atgctttttt aatcaaaaag gggagaaagt
   109681 agggaataaa gtgggaattt ctggggaaaa actggggaat tttctaattt ttaaataatg
   109741 ggagttcatt ttccttaatt cttggataaa gcatatccat aactttatac actaatcttt
   109801 cccttacaca tctacatgtt ttcctatctg agttcatctc taaggatata taaaccatac
   109861 tatttttcat tctactatta taaaacagtt taaaaaaatg ttcttctctt atatctaagc
   109921 atgtaagtgc attttctatt ttcttctttt ctatttcttt atcttttttc agttttttca
   109981 atctagtaat atctctttct ttttttataa tctcattctc aacagttgaa ttaaaagcat
   110041 atgttggact tactttttca tcatatccaa cagccttaca cccaaatatc tcattttctc
   110101 tactttctat atctaattca agattcttaa tttctgcact taaaaattta taatgatgta
   110161 atctaccttc tactttttta aatagttctt ttttattgat attattatcc atacttccac
   110221 actcctgttt atgttataat aatcttggat aaaagtttta tatttttgac aagtggagtg
   110281 tgaaagcact ccttttcctt ttttttgaat aaatttaact tactattgat aattgactat
   110341 ttaaaagtct tatttcttct tcaaacacta taggtaactt ataattgttt acaatctcta
   110401 atactttatt taattgacaa cgctttatag ccttataact atctactcca aactctcgtt
   110461 taatctgatg gtatatatca ttgtatactt tacctcttaa agatttattt ttataagcct
   110521 tacttccatg acctcctagt gattttgttg ctaccttctt aacttctttt acaatacttt
   110581 cacattcaat attgaatagt ggtgcatcat ccataaagtt ctctaatttc tcattaacat
   110641 tctctatttt agtttctaag acttcttgtt tcttatctag cataaatata gcctgtaact
   110701 cctttgatgc acttaaaaga ggattattta gttcttttct catagagaaa tatccatcaa
   110761 ctaacttctc atataattcc caagctatat catcttctaa tatttttaat aattttgcat
   110821 aacctctttc agataatata taaatcccag ataataaccc tttgtttttt aaccctctat
   110881 aagaattaat tgattgttga gtaaatccta attcttttat tttggtatcg tccaaaccga
   110941 cacctaacaa atctaatata tcttttccat ctttaaatct ttttctattc ttatttataa
   111001 gctcattaat ctgtctagat tctctattat gtatctcggc tatatctttt actagcattg
   111061 ctttcttatg ttctccaaat ccaccctcaa tgttatgaaa tttcattccc tcgatttcta
   111121 aagttccaag tactgttatt tctttattta tattttcatt cataatttat ctctcctttg
   111181 tcgtttgata tattctttat ttagcttttt cacattttta tgaaaaacta agggcataat
   111241 ttaacgaacg gatttttccg ttggttagat aacatcttct aatataacct caaccctggg
   111301 attatcgcta taatatttac tagctacaac ctcaacaatc tgtgtatcat ccttataagc
   111361 tatctcattg agtgaatcag ctataatctt aacaacattg tcaatatcgg gttttttact
   111421 aggtcttaac acattatttc ttttctgctc cttaaccttt ttactattac ttttagctat
   111481 agaatagtaa catcttaaag tcatttttat ataaccttca aagtaatgtt taactttaga
   111541 ttgatataac catcttatta gttcctcata atctctagtc ttattaggtg tataggtcct
   111601 tttagtagcc aaaataaacc taggtctttc tttaccaatt ggttctccat ctattacaag
   111661 aaaaactttc attttttcac cttcttagcc tttttcctac attctttaca acaataaaca
   111721 tccttagatt tttccttaag ataaaataat ttgccacacc aactgcatct tatccttttc
   111781 aaagaatcac ttccttttaa ctcacatatt taatctattt caatttcgac tatagctcta
   111841 cttaaaagct tcacattata attttctttt atattttcct catctttttt aaaagctctt
   111901 gcttcttcta agtcagtaaa tatagagctg tatacgttcc ctttttccca ttctcttgtt
   111961 gtctgccaag tcactttaaa ttctgtaata accatattga ctgctccttt tcataatctc
   112021 actccctagt cgcaaaatct atttataaaa ttctctacgt atctatattg ttgtttaata
   112081 taagcatcat cttcattacc accagtagcc atccagtcac atattcttct atctacatca
   112141 cttaatatgc caaatgggat atcatactta tttaaagcat catttaactc tcgtatgttg
   112201 tttatctcaa ctttatttcc agtattcttc atacaatatt tccccttttt caacttgttt
   112261 atcttctatt tgtcctagca ctctttcata ttctttacga ccttgccatt cttttattac
   112321 agcattttca atatcttgta caaatatagc taactttcca tttacattcg ctatttttaa
   112381 ccatataagt tcatgtgtgt tattcttttc tacccatatg gtaatttcct tattttcttc
   112441 caaacatata ttatttagat atatctcatt atttatctta tacatttgag tagtaatcat
   112501 aatcgcacct cttttataag tcaaagtaag tctataacat tctagtttca ttcataaact
   112561 taccttgact acttaaatta tttaaaccta gactatttgt ttccttcact ttccatttta
   112621 attaataatt cctttatttc agtagcttct tcttttatac atttaatagc tagtttaatt
   112681 tcttctttta agcgaatatt taattcttta tttgtaaaag taagcggtat tttagtacca
   112741 ttttttctta caattgatat atttattttt ttacactctt ctatttcctt taaatattct
   112801 cttaattctt tttcatcttc tttcgctctc tttatagcct caagtatagg aataacagct
   112861 actttatatc cttctggaat atcatttaaa tttattttca tttttaaatc tccttttcta
   112921 accaattttt atatgttgta tcacaatctt tgctttcgca atctacctta tcatttatgc
   112981 aactaccaca aatctctttc ccaaatttct tatacacttc tctttcatca agattatttg
   113041 acttgcacat ttctttatta gtcatatgct caccttctct gtttgaaaga aacttatctg
   113101 tctttcattt tctatatctt cattactaaa tcgtttttct aggtcatgta ctgtgacccc
   113161 attagctcta aaaggtacag gactatcttt atctaattta agcatactcc cccacaaatc
   113221 gggataatat tttcttaatg ttctgaggct atctaagctt tgtttagggc ataaatagca
   113281 accagttcgc ttgaatctgt gatgtatctc ataataaaat cctttttctt ctaaatattt
   113341 caaacaatct ttttcagtca tttttgcttc gtaaagtggt gctatacagt ttttttccag
   113401 tcttttatat ctgttaggtt catcaaaggc aattccgata tatcgcttgt gttctccaat
   113461 cgaattgaaa tatttattag caggagcaag ttttaatcga ctattacacc atgctcccaa
   113521 ggtgtatgga aaaccccata tttgcccttt atgcttacct tgtttattaa cagtataaaa
   113581 gtattcttca aaggtttttt ctgctttaat tcttgttatt ttaaagttta ttcttttttc
   113641 aaaaccatct attatgtcat aaatttcttc aaattctagc cctgtatcta taaatacaat
   113701 ttcatcaaga ggtaatttct tttctaatat caaaaggagc attgctgctg aatcttttcc
   113761 tccactaaaa ctagctacat atttcatatg agcacctact tctcattata gaaattaaca
   113821 tttttaataa ctatatctac agttccattc ccattatgtc taataccata cttcataaaa
   113881 tcctcaaaat catccatctt gccttttatc tcaaaacctg tatctgtttt tatatgtcta
   113941 ttttttaaat tcttttcaac ccatttttta tcaatattaa aactttcaat ccctttttct
   114001 tctatatggt ccttaaaact atcttttaaa tcatccttta tcgccttatc agcaaactca
   114061 tttatatcaa gtttttgttt ttctcttagc atataaagta acattcctct tacatcttcg
   114121 ccctgcttca tatcactata taaatgtgct atataagagt ccacaaaagc tttaaacatc
   114181 ttagtcttat acttatcatc ttttatctta gtagcattta agaactctgt aacaaactta
   114241 gaattagctt cttccttttc tgcatcctta tccaatactt ttagatgata ttcgtcattc
   114301 attccactta atccaactat gacggcaatt ttgactatct tagtctcttg tatgttaatt
   114361 tcatttttag acatctgtat attaaattta tcatcttcaa actcaattga atgagtatat
   114421 gacttattgt aatcaagttt taatatagca actttctttt catctttttg agagtataag
   114481 caaattgcta agtcgcaaga ttctaatgta gcattcaatt tcataacatc aaataaataa
   114541 gctgcaatct ctttagagtt atttaaaaat gaactttcat cataaataat ttgttcacaa
   114601 cacttcttaa ttagattgtt actatagtca ttaaatactg ctgttctgat gtcattatct
   114661 cttgatactt tgcttatttt cttttgaaaa aataggtcca tatcttgact aactctacct
   114721 tcaaaatcat ttagtattgg tgtatcgctg ttcttatcta aaacatgtat tataaatttg
   114781 tgtattatca taatttcacc ccttataaat ttttaaagcg ttctataatc ttctcgctta
   114841 tagtattttt tataacttcg tctaccttat ctatagttat tagtactata ttttcatctt
   114901 tagccaatgc ctttgctttc tttcttaaag cttctttact tccatatgta taatgtattt
   114961 ttctattttc taacgataat cctatttgcc atctcaatac atactttgac atttgttcca
   115021 tcccctattt taataatctt ctccatttgt taaatcataa tcttctatat catttcctaa
   115081 atccaaaatt atttttgacc catgagcaaa tattttaaat agcaaatctc caaaattatc
   115141 aaatccactc attatatctt tagatgatat ttctctattc tcgtatctat atgatgcaat
   115201 agttccatct tttctcaaca atatggagtg ttcgcatctg tatttacttt tatttggttc
   115261 tttatcaatt tcaatccatc ccgaaccata tttattttca tcaagaataa atgttatgca
   115321 atcttcatag ccttcatatt catcaatatc atatttatcc atttttaata tttccaacaa
   115381 ttcgctcatt ttatattctt tttcagcacc tacaagcatg ttatctaaat ttctttttaa
   115441 gtgttcaata gcttctacct tcattgtcat atcaatcttt tcttttactg tagttgctac
   115501 gagcacatta tatttttgta tatctaattt atctaaattt atatttatat tttcacttag
   115561 atgtttttca atttttttac taaaatcacc ccaatttcca aaaacctcat tcacaactct
   115621 ttttattgtt tctgccaatt gttttttaac tacttcctct acaaagccat tttcctctaa
   115681 ctctactagt gcatcattca taattttatt taaatccatt atattattcc cctctctatt
   115741 ttcatttttg agagtcacaa aacacttcaa caataattta taccaaaaga cattttgcaa
   115801 ctctctaaac tgtcttaatt agatattttc acttatattt cttctaacat ttcctcgagt
   115861 ttatttttta ataaatcata tttttcttta gtttctaaat ctaatattct aactcttcct
   115921 cgctctgcta taatagctat atttgaactt tcacatatca tctgtatata atttacagaa
   115981 gcatttataa tttctaatct atcatccatt cttatacacc tcttttattg tcgcaatttt
   116041 cacactcttt tagattcaat ctatactcat aaactctacc agctataaaa cttcctatta
   116101 taagcattgt aatagctaat atattcattt ttctaacatc ccctcacact catacctact
   116161 taatattttt atagctatat caatagcttt attaacagaa cactttttct tatttaatat
   116221 cttttcagct aacttaatta cttgctccac atttgctaat accatctgac acctcttgaa
   116281 tatattctgc cttccaacct tctctagtta ctctattttc tctagctaaa caactagcat
   116341 aatctccact aatctttaag tatttacttg cagcctttgc acttttaaat attctaactt
   116401 ctccagtttc aatattaaaa acttttatag gtttactttt tgtatcatta gttggttttt
   116461 tccttatttt tttgaatttc gattcattaa gtttcagctt tattttctta ctttcatttg
   116521 cttttcttac ttttcttaaa ttaagctcaa acatatcttc tatatcaata gttttttcta
   116581 aaaacgttcc tgcatctaac caaattttag ccatatctaa ttcctcctac cttatttaac
   116641 ttcaacacac cattccgaaa ctacaccaaa attaaaccaa aattcatttg gatagcaaac
   116701 atagccatca tcaaaagttt tttcaacagt aaattcaaca ccttcaatat catcaatcca
   116761 aagttcttta tattttttat gttgttctac accattaatt tccataaatt tctctttatc
   116821 aaacttataa gttttaccta tctcaaatct catattgtta gtcctcacat tttcttaata
   116881 attcttctaa gcaactctta catataacaa ttacaaattc tctaccatgt aaatccataa
   116941 cctttgtatt tgtaaactgg tcatcataac tctcaactag aaactcccca caaacactac
   117001 atatagctgt tctactcatt tttatccctc catttttaac ttttaggaag taatattgta
   117061 taattactcc ctagactatt taacttaatt aaaaaggtat atcgtcatca tctattgctt
   117121 gaaaaccttg tgggtctaat cctggtggta catattcttg tttagcatta ttatcatttt
   117181 tactagaaag tagttctaaa gcatttacat taaccttagt aatagatttc cagcaaccat
   117241 tttcatcttt gtaattatat atatttaact ctccaacagc atatataggc ttacctttaa
   117301 caagatattg cactaaattc tctacatgtt ttcctaattg ctcgcattga ataaaatcag
   117361 ttattttatt tccattttta tctttaaacc ttctatctac tgccattgaa aaggttattt
   117421 ttggagtacc tgaatttgga aggtacttca attctgcatc tgcaactaat cttccaacta
   117481 aagttattgt attcatttaa ctagccccct tctatttttc ttcctgttct tctgtatact
   117541 caacaaagta agtataagtt gtcttgctat tttgcttctc tctagcaacc tttactgtat
   117601 atccagcttt cccaagtaat cttaataact ccaatctatc ttgttcattt aaagaaccac
   117661 ttctttgtgc atatattctc gccattttat acctcccctt ttctaggaag caatatattg
   117721 atatttactt cctagaagtt taattttatt taaatttaac cttttggctt ttcttaatta
   117781 tgtcatctag ttcgtcaggt gaatattgag taaatgtttc attgaagtta tgaaacttat
   117841 ttttactcac attaggagta ttcacagctt tactattaga ctgcttctta tcctgtttat
   117901 tctttttctt cctctcaaac tcattttgat actctgtaag ttctaaatta gtttttacac
   117961 ctgcttctat ccaattattt aatattgtct ttacatactt ataattctta actccatttg
   118021 ctattgcttc atcaatagct cttataatta catcagcttc cattccatca tctaagtaac
   118081 tcattaactc tataaagtta ttaggagtaa tcacacctat atatttttca aagtattttt
   118141 ttatgtaggt ggttttgtct ttattggatt gttcattaat aacaatagta gtaatatcat
   118201 tatttacttt aaagtcatta cttactactt ccgtgttttc cggtttccga gaaacccggt
   118261 ttccgggaaa tccggtttcc gggaaatcag tttttcggga ttttaatttt tgtggatttt
   118321 caagtggtat ctcatatact tcgtaatcat accctccaag cattttatta gtattagaat
   118381 ctctacaagg ttttcttgtt atatatccat tttctataag ttcttttaaa atattcgctg
   118441 tagaatctct gccattttta ctccttttat ataagtcatt aacatagatt ttccaatggt
   118501 ctggcttact aatcagatat gaatgtaagc cttttgcttg ccagcttaat tttgcatctt
   118561 ccaaacaagt tttatttaaa actacatatg gattatcttt gtctttgctt actcttataa
   118621 tccccaatac tatcacctac tcttgttttt gcttctctaa aatgctctta tatccattta
   118681 aaactttctc atactcctgc ttagtcaaat ctactgctaa ctttccaaac ttcttatata
   118741 cttcactatc aactctattt ttatcttttt ctatagattc tcctagcgaa tatagtatat
   118801 ttaattcact ctcattaact tctttttttt tctgctcatt tccatgttta tttgttgcat
   118861 cactgtcttt tgtatcatca atacaaaata atccatttaa agcatacttt cttgcataac
   118921 ttgatacact tccagttact tgtgctaaat ccataccttt tttagtttca tcttctctag
   118981 ctaatgcctt tgtagatatt ttttctcctg tttctgcatc tattaaagtt gctgtagctt
   119041 ctacataaaa tctatttcct atctgaacaa tattatcatc caatataacc aatgcttttt
   119101 cttcttttag aataggtttt aaaccttcta aaatatcctc acaactcctg taattgtatt
   119161 ttctgaaatt attgtattgg tttttaggag cttttaaagt attctgtata tttacaagtt
   119221 ttatataaac attattagtt tccatggtcc tcacctactc ttttttagct tttggaattg
   119281 ttagtgtagt tccatattca atcctgcaac cttcaacctc atgacctttt ttaataaagt
   119341 ctttaatgat attcttatct acttttacaa cttgctctac tgttttatat atagcaggta
   119401 tcttttcttc atcttctatg actaagctac ctgctgactt tcttatactt atatttccta
   119461 aaattgtttc tactttttta gtaccaagta attccataca gtcttttata ttgcttttta
   119521 atctatcaag agtattcttc ttaaccttct ttaactcttg taacctctta atctctgaat
   119581 ctatagagtt tatatcactg tcaatgttta atattactga cactattcta gtgtttttat
   119641 tttgtatctc ttgttttatt atttctttta tttcctctag tttttcagct tcatttcctg
   119701 ttgtttctgt taaaccttct tctatttcta ataaatctgt agttaattca tataaagtac
   119761 tcataatttc cctccgtttg tgctataatt agcttatatt ttatattatt ttggaatcga
   119821 gccactccta atggctcttt tctatatctg aatatctata ggtctatctc tttcaatttc
   119881 ttctgaaatt aattcaaata tcttgtaatc ctcgctttct tcatattctt ttatttcaat
   119941 ttgtgtatct ataattttta gtaatgactc agcaaatatt tttaatcttt catttacact
   120001 tttttctctt aaagcattac ttaactctat ttcatctaat acatctcttt tttctttttt
   120061 tctaagtttt gtataaagtt cctcattttt atttatttct aaattagctc tatttagttg
   120121 ttgctctact gcatttctta ctatagttaa acttttcatg attaatcccc cttaattttt
   120181 aatttacttg gtaaatacaa gttaactaac tctatatctc tgttgtattt tctaagacct
   120241 tcaaaacttg cttttatttg cttatcattg caaaactgta cataagctat tagtactctt
   120301 acattcaact aaatcacccc ctctctaatt tctttcattt ctctaagcat ttctttgatg
   120361 ttttttcctt gatttctagt tataaaatca tctaattcat aactagaaac tttagttgcc
   120421 cctatatcaa ctgacttcaa aagcccattt tttattaact catatccaaa tactttatct
   120481 attttcaatc ttttacttgc ttcttcaaca gacataagat aatcgggata acctttactt
   120541 ataacaattg ttagttcttt tggttctaat aattctattt tcgaagtttc atttaagtac
   120601 tttgagattt tatttttata gttgtttaaa ttcatttcta caactttacg gataccttct
   120661 gaaaaacaaa ttgatatatt atctaggtca ttaaaacttt tatcttcttg tttatctaaa
   120721 ttgaaattag atatattgcc caatttactc actccttttc aaaatattct gtatttaatt
   120781 tttatcttcc aactagttca tctaatgtaa tgtctaaata gtcggctatt tttattaatg
   120841 tatctatagt tggattttta ttttctcctc ttaaaattgc atataaattc cctgaatcta
   120901 cacctatttc ttttgctaat ttccatgctt ttaaatctct atcttttaaa attttattta
   120961 tgttgtcatt aattgccatt attttcctcc tttgatatac tatatttgta ggatatatcc
   121021 tatatctttt tatgaaagtt ggtgatatta tgcagttcag taaagatata ttacatactc
   121081 ttactttaga aattcttaag gaaaaatatg attttaaaag ttcttctgaa gaggaacttt
   121141 taaaacatta ccatgaaatc tttttgaaac tttcagaagt caataatagt ttttctaaag
   121201 gcgatggcct cagtgtcttt aaacaaatgt aggtactaaa ttatatttaa gagcttcttt
   121261 gcaaaaatct aaaatatctt ttgaggaaag gatactttgt tcattttcat tcaatgtatt
   121321 aagtatcctt ttagctattt gtaactcttc ttttgataat attaattccg tttcattatt
   121381 tacattgttc actacacttt caaatgaaat tttcatttaa ttacacactc ctttttaaaa
   121441 tattctgtat ttagttttca aagtgctgtt atattttaac ttaacattga taattgattt
   121501 actaatttca atttgttgat aaagtatatt tgacctttgc ctgttacttt tggtgtttta
   121561 gtaatctttg tacttccgtc agggttatat attgctcttt ttttagtttc cattattttt
   121621 aagtcaacac tcttttgagt tggtgtattg taatcttcac ccttacgttt tattaagtaa
   121681 ccattatctc taagccatgc aaataatctt ttctcgcctg tatcaatgcc attttgctta
   121741 agtagttttg caagttctcc aactaatata gaatcatccg aggatgctac tgcatcagca
   121801 aacaatactt ttggttgctg taactgaatt accttatctt tttcttctat ctctctgctt
   121861 ttcttttcta ttgtcttttg agctacttgt aatgctcttg ccattatttc gtcgtctgtc
   121921 atatcttctg ttgtatgtat atatcctcca gttttacgta ttgttggtaa aacttcatca
   121981 aatacccaac tttcaaattt ttctgcattt ggtagtttac tatttacaat caatctatac
   122041 atatcacttt caggtattgt atttacttct aatatcttat tttcattttg cggatgaggt
   122101 atgtaacttt ttgttaccca cctacaatgg tcatttattg ctttacttgt gtttgcatat
   122161 cctaaacatt tagctatatc tgttgcaaca aaatatggtt tcttatcaac ctcaaccatt
   122221 cttatttgac caaattccaa tttttcaaat atctgtagat tattcatatt tattcctcgc
   122281 tttctacatt gaatttattt tcttttttta ttttctcaat aaactcccaa catgcatcca
   122341 caataataga atttttactt tttccacatt ctttggctat attctgtaca tattgattta
   122401 attttgggac gagccttact gtcattctta ctttttccat tcttattcct ccctccttat
   122461 gacacttatt cactgtctat aatcattata ttatgacact attttagtgt caagactttt
   122521 ttaaatattt tttgtataat gtcattaggg aggtgtcaaa atgactacta ttactgtaag
   122581 aatatataca ccattaaatg aaaatttaga aaaaatttct tatcaaacag gcattctcaa
   122641 atcttcgctt attctatacg ctattaatga tattattaga aattcaaaag ttaatgaact
   122701 tcaatcaatc tcgtataaaa gtgatgatac tgttcgttct actcttagga ttcctggtgt
   122761 cctaaaagag ttgctagaga aaacagctaa agaaaataat ttatcagtca attctctaat
   122821 aaataatgct gtgcattcat tttgcatatc tcattggtta atttatcttt gatatataca
   122881 accaacacgc aattattaca atagatgcaa taggcattcc gatttcctta cttaaatcta
   122941 tcaacgcttt gtacaagtct tctggtatac gaagcgttgt ttgctcgtgt ttcaattcaa
   123001 tcacctcttt tgaatattct gtatttagtt ttcaaggtac tgttatgttt taacttaaca
   123061 ttgataattg tttgctactt ttaaatttat taatgaagta tatttgtccc ttaccagtaa
   123121 tcttaggtgt tttagtaata cttgtatgac catctggatg tactcttgta ccttcttttg
   123181 tttctataac tcctaaatct acactttttt gagttggtgt attgtaatcc tcacctttac
   123241 gttttattaa gtaaccatta tttcttaacc agtcaaataa tctattttgt cctgtatcaa
   123301 ttccattttg tctaagcaat tttgctaatt ctccaactag gattgaattg tcagaagacg
   123361 ctaccgaatc agcaaacagt acttttggtt gttgtaactg gattacctta tccttttctt
   123421 gattttctaa ttgtagttgt tctttttctt caacttcgat taataactgt tgcagtgctt
   123481 ctttatatgt agttggtaat ttaggttgtt gttcttttaa ctcttgctcc atttcttcaa
   123541 acttagttac ataaattgct gtaaatataa tccctttttc tcctgtcatt ttattagcta
   123601 ccatatcgca acctttttta gttaataagt agcaaggttg gattttattt tgagtattta
   123661 tataagtact ttctataaag aaatcttgac tcttcaaatt tgatgagtcc tctaaaatct
   123721 tcttgtatcc tcttatatct cttaataaat tatcgtgctt cttttctatt aattctgcta
   123781 cttctctact ttcaactaaa aattgattat tttgcttgat tatggttaga ttcttcatta
   123841 ttattgcccc tttcttcttt tattgctatt ttagcaactt catctgaaaa aaaataatcc
   123901 gcagatacat tatataattt agatatcttt tttatttcac ttgctttaaa ttcgtttttt
   123961 ccttttaatt ttaatctaaa accatatgag ctaagaccta atatatctgc cacatttttt
   124021 tgggtgtgtc tattttcctt catcaatcct tctaatctat ttaagtacat taaatcactt
   124081 cctttttgct attttggcaa cttcatattt atataatatc aagttttgtg attatagtca
   124141 atacttttgt tgctttttta gcaaaaaaaa ttgtaataat taattttgtt gctataatat
   124201 aaataaaagt tgctattttg gaattaatat aaaaaggggt tgtgcaaatt gaataggata
   124261 aaagaattga gagaagaaaa aggcatctcg ctagacaaat taagcgagga tttacatata
   124321 aacaaatcta cactatcaag gatagaaaat ggtttaagag aacctaagaa aagtacaata
   124381 gaagaatatg caaactattt tgatgtgtct acagattatt tattaggaag aactgatgtt
   124441 agaaatagct tatttataaa taaaaacgaa aaagattatg atgctgaaaa ttttaaaaca
   124501 gaaaaggagc ttattgagaa tatgtatctt gacgaagata tgaaagaagt ttttaatata
   124561 tttagcgagc taagcccaga cgcaagagaa aaagcattaa aagttgcaga attattttta
   124621 ctagacgaaa aaaataaaaa atagtttatt tctgaaaatg aatataataa aaaagaggaa
   124681 tcattcctct tttttattga ttttatgtat ttctttcact tttattttat attcattgat
   124741 tttattttta tccaattctt tcaacttttt cattaataag tttaacttta aaatatcata
   124801 atatttcgtc ttattcaaat atatcatccc ctataaaata ttttatttat taattccacg
   124861 aaacatacgt tcttaaaaat agttacaacc acctcttttt caaagcttaa aactataaaa
   124921 taactgtaaa atattattat attttatagc ttctattatt tttgctttat ctagataaag
   124981 ttatttctta actacattct agcacaaatt tccaacaaaa agtgtgcgaa tattgcacat
   125041 ttattacaag aaattacaca aactaacata tataaaatta tctaaaaggt aggttaaata
   125101 tatgttaaaa gagttacgaa aaaagaagaa attaacacaa atagagttag caaaaagagt
   125161 tggttgccac agaagtcaaa tttctaggtt ggaaaataat gaggataaag atttaactat
   125221 ctctattctt attgaattag aaatagcttt aggattggaa gaaaaatatt tagtaaatta
   125281 ttttgctgat gaatatatta aaaaaagaaa attacataaa taattcgaat gtttctatca
   125341 aatactattt ttaatatata atattatttg aggtgaataa attgaactta agttttaata
   125401 aaaagaaaaa atttgaatta agcaaagaat aattggaatt aattgaaaat tggttaggta
   125461 ataaatatgc aggagatatg acgatacctg ctattgttga cttttcttta gaaactgata
   125521 ttgagtatga aaaaatagtt gtttatttgg cagaaaaagt gctggaatca cgtgataaaa
   125581 aacattaaat atgtatctaa ataaaaaaga ctattaatta taaacataaa actttgtttc
   125641 ttatagtctt ttttatttat tttatttaaa ttgatatatg ttattatata attacataaa
   125701 aaagcttttg agaggagaaa ttttatgaaa ggcggcgtaa gaaaacgtgg aaagaagtgg
   125761 tattactact ttgatgcagg tatagtagat ggcaagagaa aaaaggtaga aagagttggt
   125821 ggaaacacta agaaagaagc tgaaaaatcg ctccgtgatg caataaatga atatgaaaac
   125881 gctggtatag tgtttgatga aacaaatatg agtttatcag actatcttaa cttttggtac
   125941 aaagagtatg tacttcttaa ttgcaaatac aatactcagg aaagttatag aaatttaatt
   126001 gaaaatcata tagaacctag acttggtaaa tgtaagctaa aatctataaa tccagctatt
   126061 attcaagaat ttttaaataa taaatcaaaa gagacataca cacaaaacgg agaagaaaaa
   126121 cactacacaa aaggagtttt aaaagcgatt tatgttgtat taaatgctgc tttaaaatct
   126181 gctgtttacc cttacaaact cattaaggaa aatcctgttc aatatgccag tataccaaaa
   126241 aatgttttaa aggtaaaaaa tgagtcagat aacaagacta taacactaga tgagttcaat
   126301 aaaatactag aaatatatcc taaaaataca aatatctata ttcctctact tatagggttt
   126361 catacaggca tgagaaaagg agaaatatta ggtctttgtt gggataatgt tgatttagat
   126421 aataatataa tcaaagttag aaaaaattta ataaagagaa aagtttcaga atttgaatta
   126481 gcatcaccta agacaaaaac atcaataaga gatattaaaa taggtgatac tttgtctaga
   126541 atattaaaag aggaaaaatt gaatcaaaaa aaacaaaaaa ttaaaattgg aaaatggtat
   126601 aaagaaactg agtatgattg ggtttgtaga aaaaaagatg gctcatttgt aaatcataac
   126661 aacattgatg cttgtgtgag aacaattaac aaaaaattaa accttgactt caacttccat
   126721 tgtttaagac atacacatgc tacattatta ttagaaaatg gagctaatat aaaatatata
   126781 caacaaagat taggacatag tcaattatca actactatgg atacatattc acatgttaca
   126841 agtaaaatgg aaagtgaaac agtagatatt ttggagggta ttttacaata atttgccacc
   126901 gaaaaaaaat tatggtggca aacaggtggc aaaacgataa aaaacattct tttttttgct
   126961 caaacactgt tattttgcta ttttatataa aaaagtcgta tttctcacag ttatacgact
   127021 tatattaaat tctttacata agtctccttc agatggaagt ttatctcctg gtttatatat
   127081 gccagatgct atttgttttt ttatgttgtc atatagttgt tgatataaag gaacaaagga
   127141 atttacttct aaatccattt cttttttttg tctcttttca tccattttgc tcacctccct
   127201 atgtaacatt tttataacat tatataacaa gttctttatt acatattata acaagatgaa
   127261 atcgttgtca attttttttt aaataatttt taatttgaca gtattttctt ttattttctc
   127321 tagtgtgaca aattgctatt tttacataaa aataagactg ttgtacaaca gattaaattg
   127381 tttatacaac agcctttatt cacttattac atttatattt ttacttataa atttatatta
   127441 aaaaatgcct tatatccctt atacatttca tatatgtcta ctttagagac aatctcatgt
   127501 ggtgcatgca tatttaaaac tccaacacca cagtctataa cctctgcacc ttgatttgcc
   127561 aatatatggg ctatagttcc gcctcctcct tggtctactt ttccaagttc agcagtttgc
   127621 catattacat ttcctttatt aaaaattccc tttacttctg acataaattc agcattagca
   127681 tcattacatc cactctttcc tcttgaacct gtatacttag ttaaaactac tccatttccc
   127741 atatatgccg aatttctctt ttcatatgct tctccaaaat ttgggtcata tccagcagaa
   127801 acatcagctg ataatacctt actatttgct aaagctcttc ttactttaat atcacaataa
   127861 tctccttcta aagcaatcag ttcagccaca gtattttcaa aaaactttga gtgcatacct
   127921 gtattccctt tagaaccaat ttcttcttta tctacacata atgcaactga agtaaattct
   127981 ggttgttcag tttctagtat agcttttaca gcagcatatg aacataccct atcatcatgc
   128041 ccatatccca acaccataga cctatcaagc cctaaatctc tagccttacc agctggaact
   128101 acttcaattt cagcacttaa taaatcttct tcaactatat tgtatttctc atttaaaatc
   128161 tttaatatat ttgctgttat aggttctttt tcttcatctt ctaaaggaat attcccaatt
   128221 aatatattta aagcttctcc actaattcct tctgatagtt tcttttgcat ttggtctcca
   128281 gccaaatgaa tcaataaatc agttacacaa aatactgggt cactatcttc ttccccaata
   128341 gatatgtcca cttttgttcc atcatttaat ataactatac catgtaaagc aagtggaata
   128401 gccgtccatt ggtatttttt tattccacca taataatgag tcttaaaaaa acctagatta
   128461 ctctcttgat acagtggatt tggttttaaa tctaatcttg gtgaatctat atggcttcct
   128521 ataatcttca tacctttttc tatataattt ttacctatta caaaaagtgc tactgccttc
   128581 tctttattta tgacataaat cttatcacca caacttatgc ttcctttttc catagcttca
   128641 tctattgaaa tatagttatt ttctttagcc aattttataa tttcttttac tgaaagtctt
   128701 tcagtctttg acttacttaa aaactccata taattgcgag aatattgcat aatttgttca
   128761 atagtatttt cttttctttc aaaatcccaa gcattcttaa attcgtactt taagttcata
   128821 ttttcctcct actaagttct aatttttatt gtttttcatg tattgctcat attcttctgg
   128881 tgaaactact ttgacactat ctagtcttga tctaaagtgg gctctaaagt tttctaaata
   128941 ttctttcctt aaaatttctc tttctttgat ttcatcagca gaaaggattc cctctttatt
   129001 tttctttgct aattcattaa tcctatctaa tttcttcttg tcaaacattt tttcctccta
   129061 aaaaacctct atttatttaa taaaataatt tattgctttt tatatctaac ttgtttttat
   129121 attcacaaaa aaactcatct atattatcac ttattataga tattcccttt tctagttctt
   129181 ccatgcttgg acgagctata tttatcctaa agaatctatc atccactaga ttgtcaaaaa
   129241 aataagtccc tggaagcatt gacactcctt tgtttaacat aaaatttgta aatgcttgag
   129301 atgtatatcc tcttggtaat tctaaaaaaa agtttattcc tccacaagat tttctaactt
   129361 ttaatttacc actcaatttg tcattaatca agttttttgc caatttatac ttatcagtat
   129421 atatcttctc tatatgactc aaataattct tccaatcaaa attattcata tagtaataca
   129481 ttgatttttg aattaaacct ggtgttgata tatctgatga atatttagcc cataaaactt
   129541 tttttaacaa ctcatttggc atttctacaa ttcctatcct aagacctggc ataagtattt
   129601 ttgaaaagct ttttatatat actactctat ttttatcatc ataacttcta attgttctat
   129661 tgtcctttga ttcaaaaaca aaatcactta taaaatcatc ttctattata taaaaatcat
   129721 gttcttctgc caattctatc aatttctttt ttttatatgt tgagtaagat attccagttg
   129781 gattttgaaa attaggcata atgtatataa gtcttggttt tattttttcc aactttaatt
   129841 ttaaaatacc tatatcaatt ccatcatcta acataggtat agatattatt tttgcacctc
   129901 tacttttaaa cacttcaatt gctccattgt aagaaggttc ttccataaaa acaacatctg
   129961 aataacttat aagtccttta caaactatat ctataccttg ttgagcacct gatattattt
   130021 gaatattttc cttagtagtt tttatatttc catcacttag atactctacc attttttctc
   130081 ttaattcttc agagccaaga ccttcatcat attcaaatat tgaactacca tctttagata
   130141 atgccatatt tacagcattt ttaaatgaat cgataggaaa catatcatta gatggattcc
   130201 cattgtcaaa atgaattaaa tcttctcttt gcacaataat cttatttttc ctgttatcta
   130261 taccgctttt ataagaattt aaacttgata caaaagtacc actccctata attttatata
   130321 catatccttc attttctaaa agctcgtata ccttaactat agtagtgtta tttacttgta
   130381 aaaaatttga tagttttctt attggaggca atttttcatg ttctactaac tctttattta
   130441 ttatcaattc ttttatatga ttaaatatct gtatatattt agttgatttt ttctcattta
   130501 aatctattct gtatttttcc aaatttatca ccgctcattg tatttatatt ttattgatgc
   130561 ttttatgtat atttgatatt atttagtatg tatatataat accaaaattt ttataaaaag
   130621 gggaaatatt tatgttttac gactatcaca tgcactcaag tttctctaca gacggaaaat
   130681 ctacaatgga agaaatggta aaaaaatcta ttgaactcgg tttggaggaa atttgtttca
   130741 cagaccatgt tgactatgat gtatatgctg atgattcttt ttcaattgtc tatgaagatt
   130801 attttaagag tttagagact cttcaaagca aatataaaga taaaatatca ataaaaaaag
   130861 gaattgaatt tggagttcaa actcaattaa tggatacata caaaaaggaa gcacatcaat
   130921 atccattgga ctttataata tgttctatcc atgctataga tacaatggac ttataccttg
   130981 gtaattattt taaagataaa actcaacatg aagtttatga aaattactat ctttatttat
   131041 ataatattgt taagaattat aaagattact ctgtcttagg tcatttagat ttgattaaaa
   131101 ggtatgcacc ttatgacact attttagatg atagactatt ttctgatata attgaagaaa
   131161 ctcttaaaca agctatttat gatggcaaag gtatcgagat aaatacctct tgttatagat
   131221 ataatcttcc agacctaacc ccatctaagt atatacttca aatgtataaa gacttgggag
   131281 gggaaatcat aaccacaggt tcagattcac atcatataag tcaagttgca tgtgagtttg
   131341 actacatata ttcattacta aaaaatatgg gatttaaata tgtatctaaa tttaataaat
   131401 tgaaaccaga atttataaaa ttataaattt ttacacctcc ttgtgaatat atttaaaaga
   131461 taaggaggtg atttttttga aagtacctta tttagtacta tcaacagtta ttttatttat
   131521 atccaatttt attgtaagaa tatttggttt tttatataaa atattcttat caagagcact
   131581 aggtgaaaca ggtttaggta tctatcatat gatttttaac tttttgatga tttgcttagc
   131641 tgttacaaca acaggtatac ctactgcact tagttgtcta gttgcaaaga gaaaagcttt
   131701 aaacgataga cacaatacta atgctttatt tatatcaact ttatatatat catttttcgt
   131761 agcactaatt atatctatag ttgcatcttt caatagttct tttttatcac ttaaattttt
   131821 aaaagatgct aaattaaatc tatttatact agctgtttgt cctgctatag ttataataac
   131881 tctttcaaac gtactaagag gatattacta tggcataaag aatgtaaaaa tccctgctat
   131941 tggacaaatc attgaacaaa ttggtaaaat attatttgtt tttttacttg ttatgtacat
   132001 aaataataaa tctatgaatt gttatatagc tctattaggt atatcaattg gtgagttgag
   132061 taatattata tttatgctta tttgcttatg gcgagattca tcatttgaca ataggtatat
   132121 tataagcata aaagattttt ataattcttc tatggaaaca ttaaaaatgt ctattcccat
   132181 aacttgtaat agaatgtcaa acatactttt gcaatctata agttctatga tgataccatc
   132241 aagattagca ttatcaggaa tgacttatca acaatcttta agtatgtatg gtattgtcag
   132301 tgggatggta atgcctttta tatttttacc ttttactgtt ggttcagcgc ttattgtaaa
   132361 tttaatacca actatttcac aggaaatggc tctaagaaag cgtaagagtg taattaaaaa
   132421 aatcaaatac tccatacttc ttactttatt tgtaggcata ctatcatcaa tattttttta
   132481 tttctttgga aaagatttat gtatattagt atttaaaaat acacttgcag gagaatatct
   132541 aaaagctatg tttttagttc cactatttat gtccctaaat caaactctat ctggcatttt
   132601 acattcaata agaaaagaat tagcttcaag tataaatact attactggca tgttaattca
   132661 actaatagct ttatatgtat ttcttccaat tccaggactt aatatttatg catacatata
   132721 cacaatgacg atagtatcaa tctttacttg tctattacat actatagtgc tttttaaatc
   132781 actaaaatct atacgctagt tataaaaacg tgaaggctac caatgtaaat tatacacttt
   132841 ggtagccttc cttagatgat ttttatttat aatttaaact gtctatatat ctacctatct
   132901 atctgtggca acttggcttt ccacttccat gattaggtcc acattgcgaa aaatcacata
   132961 ctttagagaa agtatcaaca agtcttggtt ggattggatt tggtgatgct aaaactacta
   133021 tttgttcact tattaatgtg ctaactgttt cttgtaagca aagtactaaa tctatatcat
   133081 ttggtataat taattcatag aaaggttcac aacattcgtt gcattctaat tttaatatag
   133141 attttcctat acaatctaca gttaagttag tttgatattc ttgtcttaaa gtaacagctc
   133201 ttccgtcagc tggcaagcat attggtgctg aaagtgtgtt aaaagtaaat tctacataat
   133261 caactcttct cttacatcca cctcctgctc taactgctgg gaaagctaat gcaacgaact
   133321 ctgtacatcc acatctacct cttagctcta gtactaaatt acgaactgct acagttaatc
   133381 ctctttgttt ataagctact gatttgcctt ttccttgtct acagcactca gagtttcttt
   133441 ctccacaaac tgcaaattca aaagttgttt cacagtttct tcctactata tctcctaatg
   133501 ggtctaaatc gaaatcttct aaagttgtca ttcctgtgtc tataacgatt ccatcattac
   133561 ttaagcatat tttttctata gttacacttg cttgacctgc acttggaact gaaccaaata
   133621 cttctactac ttctgtttca aaagttaatg gctctccatt tggtcctgtt gcatctgtaa
   133681 atgtttggaa ttgcatagta tcaaatattc tattagcctc tattgcaaat ggcactgcat
   133741 ttgatacaga gaagtttctt ggagatatag gattacagca ttctggtcca catttgtttt
   133801 caaaacattc atctgaatcc atttcacatg gttcacaatc acatttacaa ttgtcatggc
   133861 atccacaatt gtcatcacat ggattaggtt tgcatggatt gcatgggtta ggtttacatg
   133921 gattacatgg gttgcatgga ttgcaatcat catggcactc acacttatta tcagtattac
   133981 atccattatg atggtgtgat tttttaaaac ctctcatgtc ttctgaattt atttcatctg
   134041 tatacacttc ttcttcattc attgtagaca ttggctgatt catcattctt cttttatttt
   134101 ttttataatc ttgcattttt cattgccctc cctgtaagcg attcttatta agtctttggc
   134161 tttttgaagc ctaattaata ctatgctttt ataatcttaa ttgttacttg ctttttgaat
   134221 ttatcaataa ttaggcgtat ttagtagaaa aatgcatatt aataaaaaaa gtactactat
   134281 ttgaaatagt agcacttttt ttgtcccgaa acaccggtgg ctaagtaaat tcacacccta
   134341 ggcactccca ggtgggtgac ttgccagtaa cctttaacgt ccaaactaac taggcatgtt
   134401 ataatttacc agacacggtc tcccgtattt catttgtagg ttgaatttaa aaaagcctta
   134461 tcgtatgttt caggatttca tattattatt atataataaa ttttgaattt tttaaagtgg
   134521 ttttatatag taattgagat aatcttattc tatcattact ttttcttcct tttttcttta
   134581 tgtatttagt taattatcgt tttttcttag ctctagtttt agtatttttt tcattataat
   134641 tgtattcgga ttcttgctca ttaatgttgt atagttcctc atcgtatact atatcttcat
   134701 cattttctat attttcatag cctgtgttct tatcttctac taattcatct tcattatcct
   134761 ccatttcacc ttcatctgtt aactcatcat catccaattc tttgtcttca caatctaatt
   134821 cttcgtcttc ataatttaac tcatcattat tgtcttcatc atcattatta ctatcatcac
   134881 ctcttaaaag acttcctaac aatttgagat tattcatact accaagattg tttatatttg
   134941 ccaaagagct caaactaaat ccaccttcac caaagtcatc tggtaaaaat aattctgcaa
   135001 ataaatctat cttctttttc attcctatag ctttttcaac tgaatttttt cttttttctg
   135061 ggaatacatc tataatttcc tttatcatca tattcttttt atcatcacta tccatttttc
   135121 tgaaaaaatc cgtttcatct tctgtatcta ccatatctat attatttaat ttttttattc
   135181 ctctaactaa atctaaaaca ctttctattt ttattagtat ttttctttca tctcttgaca
   135241 tgtatttttt agttcttgtt attatttcca ttcccatttc taaatcttct tcacttaaat
   135301 ccatgagcct taaacctctt tttatatcat ttgcatcaaa ccttaaattg ccatgtgtag
   135361 actgtgaaag tttatcattt gcattttttt tgttttttct aactctatta tttccttttg
   135421 atttattttt atcatcaaat atagagatat taccattact caatgcaatc actccaatca
   135481 aaaatagtaa gttattcaag acaattcccc cttatattat ataattgccc tatattaaag
   135541 tatgtttttc atattttaat gttccatttt taaagctcag tgcatatata ttatctataa
   135601 gaatttttat ttatattata tatcactcac aattcaccac ttcaatatta tttctatata
   135661 taaatagtat gaatataatt caatatatat ttatagaaag gggttttttt atgaaaaaat
   135721 tagatacaga gtcattagaa aaaatggcta aacaaaaaaa tattgacaag gataaaatag
   135781 aaaagatggc tgatagttac aaaggaaaat cagaaaatga acttatggag gaacttataa
   135841 aaataggtaa gaacctagat ggcagagatg aagtagtatc aaaattcaaa gcatttttag
   135901 atgaaaatca acgcaaaaaa ctggataata taatggaaaa aatctcagac gcagaaaacc
   135961 aaagagatac taaaccagct aaaactaaga aggctaaacc tactaaaggt aagtcaaatt
   136021 cacctgcgcc aaaaaataca ccaggtagtc aacaaaaaaa atctaaaagt ttatttaaga
   136081 aaactaaaaa gtctaaccct catgaataga taaaaataaa ctatttaagt aattagataa
   136141 ttatttttag ttaatctatt attaaatttg atattattga cataaaaaat caggtagtgc
   136201 cttaggcact acctgattga ctttaatagt tttatttttt tctttctgtg acactttctc
   136261 tatcaacaat tctataaggt aattctattt tcttattttc aattaattcc ttatttatta
   136321 attttataac cattcttatt gctactgctc ccatatcgta tagaggttga tatactgtag
   136381 taagtttagg tctatacatt ctagctatct taacatcatt aaatcctgca acagatatgt
   136441 cttctggaac cttatatcca gcatcacata tagcatttat agcacctatg gcagcctcat
   136501 cacctgttac aaaagccgca tgaggtatta ttccatcatc taatagttct ttcatactat
   136561 tgtatccact ctcataatca gttccaccat acttaatcaa actcttgtct aattctatat
   136621 tgttatttga aagtgctttc tcataaccag caagtctttc catttctaaa acagtatcat
   136681 ctttactcgt cattataaaa gctatctttt catgaccttt ctttataaga tgctctgtca
   136741 tatcaaaagt agcttcttcg ttgctagtac ttactgtata tatatcataa tttctagcag
   136801 ttttacttat atatgtcgct ggtattccac aattttgtat atagttgata tgttcttgtt
   136861 caactatcca tgaaatcata actatacctt ccacttgttt tgctctcaat agatttatac
   136921 tcttaagttc ttgttcctta tcagagtatg tattcgctaa aagaatatca tagtcataca
   136981 ttttagcaac ctcttctatc ccatttaaca cctcattaac aaaagaatct gaaacttctg
   137041 gaactattac ccctattaat tgactcttct ttgttactaa gcttctagca agtggatttg
   137101 gtatatatcc agtctctttt ataacctcta aaactttttg tttgacttca tcagttacag
   137161 gttttgaatc atttataact ctagatacag tagatattga cactcctgct tgtttagcaa
   137221 catcttttat cgttatattg cctttcatct tcatcctcct tattttacta aatttatcta
   137281 aaactgaacc aaatttttga aggttcctat tttaactaca tttatataag tttttatttt
   137341 accataaaag caagtacatt taaatacatt atattttata ttatacccta tattcaacaa
   137401 atttaataat attcattctt aatttaaatc atattaaaaa ataaaataaa aaaatgctgg
   137461 tataaaatac cagcattttt ttattctaat gatttaagta ttagcagccg caacctactt
   137521 caccatcaaa gaatccacca catgaacaag ttattagcaa taatattaag aaaggtatcc
   137581 atgacattat gtcaatgtct ctccagcaat cttcaaaagc taagaatagg aagaatagta
   137641 ctattatcca ccatcctcct ccaccaaagc ctccttcttc tccaaaaaat ctatctaaca
   137701 taacaaagcc ctcctttttt taataactgt gttcttattc taagcatcca ccacagcagc
   137761 aaagtattaa taaaactatt aggaatggta tccatgccat tatgtcaaat tctgcccagc
   137821 tatctccaaa agctaagaat aggaagaata gtactattat ccaccatcct cctccaccaa
   137881 aacatccttc ttctccaaag aatctatcta acattatacg ttacctcctg ttgatatttt
   137941 gttgagcttt tcgctcctaa catatactat gcatttggtt tccattttgc taatgtattt
   138001 ttactatttt tttaaatttt ttaatttgaa ctaaaaaagg taaaaccata acttgtataa
   138061 gttactggtt ttacctattt aataatcaat attttttagc aacaacaacc atcatcgaag
   138121 ttaaataata acaatactat taatataacc catatccata tattgtcatc gcataataag
   138181 tcttctaaaa tgtctgtgca taatagtaag aatactataa ctattattat caacatttta
   138241 ttcccaaaaa atccttcgca tcctccaaag aaacgttcca tattgtcttc taattttgtc
   138301 ataactaatc ctccttgaat cattaagaga ctaagttttg tctctttaat taaatatatg
   138361 tagtaataga cagataagtt acttctaaaa agtttttatt gattagttta tttatttctt
   138421 tttcaccaag tttattgtat ctatcaactt catccagata atcttttttc tcctctgata
   138481 tagtatagat taaactttct attgatttta ttttgtactc cttatatctt tctatcaaga
   138541 aggatgtttt tgaattttct attcctttct ttacatgcat taaccttgat atgtagtctt
   138601 ctttttcatt agatacataa ctctcctttt cagctacatc ttcaaggatt aaattggtct
   138661 ccattacata atcctctata cgttgcatat ctaaagttat tgaattataa taaaaattta
   138721 ctgctataag taaaaacatt cctactgaag ttagtaatag tcctacatat ttcatagcat
   138781 ttcctcctaa gttatatttg ttatcaataa agtttattca tcaaataata ctttattact
   138841 acatttataa aattttatta ttttttatag attccatatt gaaaaattct tgatattata
   138901 ttaaactaac attaaaatta attaaaactg ctttaggagg cttaaaatgt ttgagaaaat
   138961 aaaagaaata atagcagaac aattaggggt agacaattta gatgagataa ctatggaagc
   139021 atctttaatg gacgacttag aagctgattc attagatgct gttgaaatta taatggccct
   139081 tgaagatgaa tttggaatag aaataccaga cgaggaagct gagaacttta aatgtattgg
   139141 tgatatatgt aaatatatcg aagaaaacaa atagtatcgt tttgtctaca aatataaata
   139201 gtctgtgtaa acttctacat aataaattat attagagttc gcacagacta gattacattt
   139261 atttacaata tataaaatac acgctcttat atttaattta tatactaagt atataaatta
   139321 cttttcttca taaaatgtaa cattctttat tattatatct atagttccat cttgattttg
   139381 ttttacagta tacttcattg ggtcttcaaa atcagttaga ttccctttta tgtcaaaacc
   139441 attatccgtt tttatacttc tttttttaag ctttttctca acccattttt tatctatact
   139501 aaaactttca tcaagacctt tttcttccat atgctcttta aagctatcct ttaactcatc
   139561 atctttaatt gaattatcaa caaagtcatt tatatcaact tcatgttttt ccttcagtgt
   139621 ataatttaat atacttctta catcttcagc ttgctttata tcattactaa gagcattggt
   139681 tatccaattt tcagctgtat ttttaaatac cttggtcttg tacttatcat catctatttt
   139741 tttagcattt aaaaattctg ttacaaactt agattctgac ccttcttttt cagcatcctt
   139801 atctaaaagc cttagatgaa actcatcatt tataccactt agactaatca aagctccttg
   139861 cttttgtctt aaagtctctg ggataccaat ttcatttgaa accatttgaa tattaaattt
   139921 atcatccaca aattcaattg aatgagtgta caacttttta taatctaatt tcagtattgc
   139981 tacactcttt tcatctttaa tagtatataa gcaaattgcc aaatcacaag attctagtgc
   140041 agcattaatt ttcataacat caaacaagta agatgcaatt tctttagaat ttttcaaaaa
   140101 agtactttca tcatatatta tttgttcaca acagttttta attaaattgt cattataatc
   140161 tttaaaaaca ccttttctta aatcctcatc ttttgcaatt ctttttatag ctttctggaa
   140221 aaaaccatcc acttcttgat taactttgcc ttcaaagtca tttaatattg gaacatcact
   140281 atttttgtcc aaaacatgta ttataaattt atgtattatc atatatatca ccccattatc
   140341 ttaatttcga tattaactct ttcatatcct ctggtatatc tgctttaaat ttcaattttt
   140401 cttttgttct tggttgttca aactctaact tatatgcatg aagtgcttgc ctatttatta
   140461 gctcttcatc tacataacca tacaactcat cacctattat tccatgacct atatgagcca
   140521 tatgtactct tatttgatgt gttctaccag tttctaagct tacttctaat acagttgcat
   140581 tttctagtct ttctattact ttatagtgag taacagatga ctgtcctctt tcatctatta
   140641 tcctctttat tgaatcttct gtaggtctat aaattggctc atctatagtt ccctcatttt
   140701 cttttataat tccatcaact actgttatat actttttttc aactttattt tcactcattg
   140761 ctgtagacaa agtatgatgt gcataagcat tttttgctac tataactaac cctgaagtat
   140821 tcatatctaa cctatttaca aatcttattt ttacattttc tttttgatta tctatatagt
   140881 aactaatacc atttgctatt gttttatcat agtggctttt tgttgggtga actaccataa
   140941 acggaggttt attcaccata attatatcaa aatcatcata aattatctgt aaatttaaat
   141001 cttgaggttc aaaatttgct ttttcctcgt ctatttttac ttctattaaa tcaccactat
   141061 acacctttaa acttggtttt ttatatactc catttactaa aacactcttt tccctcttca
   141121 tttttgataa tgacctaact gagaaattta gcttgtccaa taaaacttct tttaaagtca
   141181 tttcttcttc atttgtatac gatataagat tatatctttg attctctttt ttaaacaaac
   141241 ttttacctac tttcttttat atcttcctac tttttatatc ttcaaaatca tgatattata
   141301 tattttacac tatttttgtt taatagataa taattatttt taactataaa aacctgtaag
   141361 aataacaaat agttattctt acaggttaaa ttcataatta aatatttaat ttgtaaatat
   141421 tataatctaa aactatctct taactattaa agtagttccc attccaccgc ctatacaaag
   141481 tgtagcaaga ccagttttag catctcttct cttcatttca tataaaagtg tagtaagtat
   141541 tcttgctcct gagcatccta ttggatgtcc tatagctatt gctccaccat taacattaac
   141601 tttattcata tctatattta agtctcttat tacagctaca gattgggcag caaatgcctc
   141661 attagcttca actaaatcta tatcttcaat agtcatatta gcagcttcta aagctttttt
   141721 agttgctgga actggtccat atcccattat tttagggtca acaccagctg ttccataaga
   141781 aactatagtt gcaagaggct ctattcctag ttcttcagct ttttctttag ccattactac
   141841 tagcatagca gcaccatcat ttattcctga tgcattacca gcagtaactg ttccatcttt
   141901 tttaaatgca ggtcttaact tagcaagttt ctccattgta gtgccaggct taatatattc
   141961 atctttatct actacagtgt caccttttct tccttttata acaacaggaa ctatttcttc
   142021 atcaaatttt ccttcagctt gagctttttc agctttattt tgacttgcaa gagctaattc
   142081 atcttgttct tctctagtta tattccattg ctctgctatg ttttcagcag taatacccat
   142141 gtgatagtta ttaaatatgt ctgataatcc atcttttatc attgaatcaa caaaagcagc
   142201 atcacccatt cttgcaccat atctcgcact tggtactaaa taaggagaca tactcatgtt
   142261 ttcagctcca ccaactaaca ttatatcagc atcacctaat gctataagtt gagatgccat
   142321 tgaaacagat cttaatccag aaccacaaac tatatttata gtcatagctg gtttttctac
   142381 tggtattcct gctcctaatg ctatttgtct tgctatattt tgtccaagac ctgctgtaag
   142441 tactccccct aaaagagatt catctatcat atctggagtt atgttagctc tttttatagc
   142501 ttctttagct gctgttaccc ctaactctac cgctgaaact gatttaaatg ctcctccaaa
   142561 acttcctact gctgttctag ctgcactggc aattactact tctctcatat tcattacccc
   142621 cattaaatta gatttttcat atatccgaaa ttgtttttta aacaatttta tttaaacttt
   142681 taattcccaa attcttattt attataatca tagaatccta tcttagtttt tcttcctaat
   142741 tgattagctc taaccatttt agctaaaagt ggatgaggtc tatatttagt atctccaaat
   142801 tcagtatata aaacgttcat tatagctaaa acaacatcta atccgattaa atcacctaat
   142861 gctagtggtc ccattggatg gtttgctcct aatttcatag cttcatctat ttcttcttta
   142921 cttgcaacac catctgcata tataccaaca gcttcattta tcataggtat aagtattcta
   142981 tttactacaa atccaggaga ttcagataca tctactggta ctttattgat actcttagat
   143041 aattcaaata ctgtatcaaa agtaactttt gatgttaact gaccacttat aacttcaact
   143101 aatttcatca taggaactgg attaaagaaa tgcattccta taactttatc tggtctctta
   143161 gtagaagaag ctatttctgt tatagataat gatgaagtat ttgttgccaa gatagtatct
   143221 tctttacata attcatctag taacttgaaa acatctttct ttatattcat gtcttctaca
   143281 gatgcttcta ttattaaatc catatctttt aaatcttcat aattagtagt tgaactaaca
   143341 tgacttaata tttctgcttt tgtagcttca tccatttttc ccttagtaac taacttagtt
   143401 aaatttttat ctaataaagc taaacattta tctatagcac cttgagttct actctttaaa
   143461 catacatcat gtccacaact tgcaaaagtt tgtacaatac cacttcccat agttccacta
   143521 cctattacag ctaatttcat agttataacc tcctgttatt ttagtattta tattctgtta
   143581 actagattaa aatactattt aatctagtta acagcaaata tatttttaat tagattttta
   143641 cccttttata aagttagctt ctctcttttc aacgaaagct gacattcctt ctttttggtc
   143701 tttagttgaa aaacaaagac caaataaatt agattctata tctattccag tatttatatc
   143761 agtttgagca ccaagttgta ttgcttcttt agagtatcta actgcaagct gagcattttt
   143821 agctattatc ttagctaatt tctcaacttc ttctattaaa atgtctggct caacgactct
   143881 atttactagc cctatttttt cagcttcatc agcttttata acttgacctg taaagattaa
   143941 ttcttttgct tttgccattc caaccaatct tgtaagcctt tgagttcctc catatcctgg
   144001 agttattcca agagttactt ctggctgacc aaatttagct ttagcagatg caattcttat
   144061 atcacatgcc attgcaagtt cacatcctcc acctaaagca aatccgttta cagcagctat
   144121 cactactttt ttactatttt ctatttctcc aaaagctttt gctcctaaga tactaaaatc
   144181 tttagcagct acagcatcta aatctttcat gtatgcaata tctgctccag ctacaaatgc
   144241 ctttccttcc cctgtcaata ttacaacatc aatagtttca tcattattaa tatctacaaa
   144301 tacttcataa agttcttcta aagtctttga atttattgca ttaagggctt taggtctatt
   144361 cattttcact gtacatatat ttccatctac ttcaacagct acattctcat aaactttaac
   144421 atcacttgta ctcataatac cctccccaag aaattagtta gctaaaactt cacctttttc
   144481 ttttgcaaca cttaactgac tgataagttc tggaagcact ttatgaacat ctccaactat
   144541 accaacatca gcatatttaa atattggagc ttctggattt ttatttatag caactataaa
   144601 ctcagcatct tccataccag ctatatgttg tattgctcca gatataccac atgctatata
   144661 aaggtctggt cttacagttt taccagtttg accaacttgt cttgctttat ctaaccaacc
   144721 tgcatctata gtggcacgag aaccagaaac ttctccacct ataatttcag ctaattcata
   144781 aagtatgtct aagttttctt ttccacccat tccacgtcca gcagaaacta atatcttagc
   144841 atcttctatt ttaacttgtt ttttagcttc ttttattact tgtacaactt gaactaattt
   144901 atcagcatca ttaaattcta ccttgaaacg gttaattaca gcttctttag tttcatcagg
   144961 ttcatttttc ttcataaccc ctggtctaac tgtagacatt tgaggtctga aatctttaca
   145021 aactattgtt gccattatat ttccaccaaa ggcaggtctt gtcattaata ataattttgt
   145081 atcttcagct actgcaagac ctgtacagtc agcagtaaga cctgtatgta ttctagcaga
   145141 aactctaggc gctaaatctc tacctattga agttgcacca aataatacaa ctatagggtc
   145201 agctgctttt attgcttcat aagctgcttt tgtatatggt tcagttgtat acactgctaa
   145261 agcttcatca tctactacta ttacctcatc tgcaccatag tgtgctaatg tatctattaa
   145321 accttctacc ttactaccta aaagtaatgc agaaactttt gtatcataat cttttgctat
   145381 ttctgtagcc tttcctagta attctaaaga aacagtttga attacatttt ctctttgttc
   145441 tattactact aaaacgttac ccattcttta tcccccctta aattatatga tatacttctc
   145501 ttttaattta tctatgataa ttccagctga tgttttcgca tcttcattgt atattgtacc
   145561 agctggttta actgattttg taaatgattt aaatacacta gttggagaac ctttaagacc
   145621 taaattagaa gggtcaactt ctatatcttt tacagtccat gtttctacta catcattttc
   145681 gaaagcatca tatattcttc caactttcat gtatcttggt gtgttcatat ctttaagagt
   145741 tgttataagg catggcattt taacttttaa gtcatggcaa caatcttcaa attgtctttt
   145801 tactaataca tattcacctt cagtttttat ttcttcagca tatgttattg atggaagatt
   145861 taaatgttca gctatttgag gtccaacttg tgcagtatct ccatctatcg cctgtcttcc
   145921 agctattata atatcaaaat ctatattttt taatgctcct gctaatgctg atgaagttgc
   145981 ccaagtatca gcacctgcaa atgctctatc tgttaataat atacctctat ctgcacccat
   146041 tgctaaagct tcttttaaag ccatatctgc ttgaggaggt cccattgtta taacagttac
   146101 atgagcaccc atttcttctt ttaattttat agcttcttct aaacctgctt tatcatcagg
   146161 gtttattata cttggtactc catctctaat taaagtacct gtattaggat ctagtttaac
   146221 ttctgttgta tctggaactt gttttataca aacgactata ttcataaatc cttcctccat
   146281 atctatttta atatcgacct attgtgtata ttttaatatt tatctatttt aatagttttc
   146341 ctgaaataac cattctttga acttcactag ttccttcata tatttcagtt atcttagcat
   146401 ctctcatcat tctttctact ggatagtcac gagtgtatcc atatcctcca tgaagttgta
   146461 cagcttttgt agtaacttcc atagctgttt cagctgcaaa taattttgcc attgctgctt
   146521 ctactccata aggttttcct aagtctttat ttatagctgc ttgatataca aggtgtctag
   146581 ccgcttgtac cttaacttcc atatcagcta attggaattg tgtattttgg aattttgata
   146641 atggtctacc aaattgtact ctttctttta catatttaac agtttcatca agagcacctt
   146701 gtgctaaacc taaagcttgt gcagctatac caattctacc accatcaaga gtagacattg
   146761 ctatcttaaa tccttgacct tcttttccaa gtaaattttc tttaggtatt ctgcaatcct
   146821 caaatattaa ttcactcgta gctgaacctc ttatacccat tttcttttct ttaactccaa
   146881 agctaaaccc aggagttcct ttttcaacta taaatgctga tattcctttg ttccccttag
   146941 atttatcagt cattgccatt actacatata tgtcaccagc tattgcgttt gttataaata
   147001 tttttgagcc attaagtatg tattcatccc cgtctaaaac agcagttgtt tgttggccag
   147061 acgcatctgt accagcatta ggctcagtaa gaccaaatgc tcctaatttt tctccacttg
   147121 ctagtggtct taagaatttt tgtttttgtt cttcattacc atattgatat ataggccatg
   147181 agccaagaga tgtatgagct gataatataa ctcctgtagt accacaaact ctagacaatt
   147241 cttcaactgc cattatatat cctacagtgt ctccaccttc tccaccatat tcttttggat
   147301 atggtatacc catcattcct gcttttgcca ttttttccac tgtttcataa ggaaatcttt
   147361 cttcttcatc aagttctgtt gctaaaggtt taacttcatt ttcagcgaag cttacatata
   147421 gctctttaag catctgatat tttttagaat ttaaatccat aatagcctcc tcagtatttt
   147481 ataaatattt tattttcatt tattaattaa aatctcggca acatctataa taaggtattt
   147541 gaatatacgt cgagaaattt ataaccttaa tcaaactacg ctctatattt atatgtgatt
   147601 atactaacca attatgacat taatttaatc ataaattgtt aatttaaaat caactatact
   147661 aaaaaaaaat ctcgcttttt ggaattttgt gaaatttcaa gttagaataa gatttctttc
   147721 acactggtta gagataaaat aatttgttta cgatatttat attagggtat attaaacatt
   147781 aaatattgtc tgtacatctg ttttttagcc atgtacagaa gatttttatc gtataaaaat
   147841 tattttaata gagctaaata atcatatttt tatctgacta ttttttattt ttaaatatct
   147901 tacatctata atagtatcac tcaaaggata atttttcaat aatttctaat tattttttta
   147961 acaatattta ttacattttt tccacttttt tgtcattttt ttattgtttc gaaaaaaaat
   148021 cagaattttt taactttatt ttggattatt agtttaaatt agattttcct cttagattta
   148081 taaatattta cacaaaaaaa ctacctctgt atagattgta tacagaggta gttttttact
   148141 aattcctact atagtttact atattttttt accaattctt acaaacatct acccattttt
   148201 cacacttaga aaacttctcc atttcttcac atgtaagttc tattgcagag ttactactgc
   148261 cacatgcagg aaatactgta tcaaatcttt tcattgaatc atctaaatag acttttatag
   148321 aattttttaa accaaatgga cagactccac caatagcatg tccagtaaac tccaagactt
   148381 cttctggtgt caacatttta gccttacaat taaattcagc cttatacttc ttattatcaa
   148441 tcttagcatc accagctgtc acaattaaaa ttgcatcatc tcctatttta aatgagagtg
   148501 tcttagctat tcttgctgga ataaccccag ctgcttcagc tgcaagttcc acagtagcac
   148561 tagattgttc aaattctaag atactgtctt ccttgccaaa ttgtttaaaa tactctctta
   148621 cattacttat tgacattaaa tacccctcct agtctgaact tttataaatt tcatattatt
   148681 cttaattata tctataattg atttattttt caaattattc cataatatta gcattccatg
   148741 tatcattatt ttttccaact actagataaa gtccttttgc cattggaata ttgacaatat
   148801 attctccttt atactctaca ctcataccag attcattaaa gtacctataa tcaaaattta
   148861 gtccttttgg aattacaaaa tcaacataac cttgattatt tggttttatt ccatatttca
   148921 gagttctttc agttatagaa tttttttcat taaataaatc tacatttaca tatgcagaac
   148981 acttattcat tcccttttta ttttccacac aattttcaaa cttcatttta gcactgttta
   149041 atttataact atatttacta ttattgctta ttttaaatct tacaatagta ccaacatctc
   149101 tacttctcct gctatcaaaa tcaaaaacaa tttcctctaa atgatttatt tcataatctt
   149161 tgacacttac catatctcta tatactaatt tatttatagc tatgaatagt gtaaaaatcc
   149221 ccaaaataaa aaatgaaact tttataaact tcttcatttt tagtctcctt atattttgtg
   149281 ctattgtgct ataatattaa tcaaaatttt aataattaaa cttattcttt tttgaaatct
   149341 taatagaaaa atacattgat attataaaaa ttattattgt taaaaatgtc atactatata
   149401 aatttatata cttagtatta gctatatcag ttacataatt tgaaagatat actcctccaa
   149461 ctttactata attaaaatgc tttacttgat atacaatcat actaatcatc ttcaaaagac
   149521 ttccatatac aaagtaaatt aaaatactta ctataaaacc acaaactttc atttttccat
   149581 atccaaactt aaaaattaaa ggcagtaaaa tcgtcaaaat tgctaaaaat atatttacag
   149641 aaaaaaatac atcatttaaa accatatttc taaagaacac tagtgatgtc aatttactta
   149701 gtaaggacac aattattgtt acagaaatta ttaatcctac acctaataaa tattttgagt
   149761 aaactatatc ttctatacta actggcatac tccttataaa aatccttgaa tcattttcat
   149821 aatcacactc aaacgtattt ataaatatca aataactaac aacaatactt actgtataat
   149881 atgaaattga attaaggaaa aaataaaaca caaaaaatag caatatgtac tttaaattac
   149941 ggataccatc tgaactaatc cctattatta aatcttttct tattaaattg aacatcatct
   150001 cacctcattt acataataat acattagttc ttctatagta ggatttttga ccttatgctt
   150061 atcaatttct atcaataggc tttttacttt caagctatct ccaactttaa caagtgcctc
   150121 attataatat ttatactctt tcacaccaac tatgctttct ttaattgctt ctaactctgc
   150181 tttatttgcc ctaattatct tatattcttg ttctattaat tctttcttaa cagtaaaaat
   150241 ctgatttcct ctatttataa aaacaagata atcggcaatt ttaattaaat tatcagtatt
   150301 atgagtagaa attattacac tactacttcc atttttcaca aaatcttgta agtactgcat
   150361 tatttcagtt cttacaattg ggtctatccc agcagttggt tcatccaaaa tcaataactt
   150421 agcattgtga ctaagtgcac ttgataacat aagcttttca gattgacctt tagataaatt
   150481 ttcaatatgc atattttctt ctatatcaaa cttattaagg tattcatcaa acctttctct
   150541 atcaaaattc ttataaaata aagaaactat ttttctaaat tccttaacct ttaaatgcgg
   150601 ataaaattgt aaagaatcat atacaaaacc aatattgttt ttaaaactta ttggagaatt
   150661 ttcaatagtt tcattacaaa gttcaatttc accttcatct gcatcaataa tccccattat
   150721 aatttttatt aaagtcgttt ttcccgaacc atttggtcct ataatcccaa caatatcccc
   150781 ttcctttaac tctaagttta tattatttaa cttgaatttt cctaattttt ttgtgatatt
   150841 ccttatgcta aacacatctt cacctcttat gcattttttt atacccacct atacatattt
   150901 taacacattc attacaaagg tcatttataa atttataaat taagaattat aaaactatgt
   150961 tataatacaa agtatgaaga ggtgaatata tgaaaagaat tataactata aatacaaacc
   151021 aattaaataa gtcccttgag actaaagaac tcttaactag aaaacttatc aatgctggct
   151081 ttgaagtgta ttcagatatt tatccagaca cagagcttat tatatcaatt ggtggtgatg
   151141 gctctttttt aagaacagtt agagatttcg attttcctga gattcccata atgggaataa
   151201 atacaggtca tctggggttt tttcctgata ttttaccaga taagattgat agctttattg
   151261 aagcttatac aaaaaaagat tatattattc aagaaatgtc acttcttaat gcggaagtat
   151321 atacaactac tagtggttct aatatgcttg ctgtaaatga ggttgttata agaggagaca
   151381 agtctaggac tatacaccta aatttaagcc ttgataataa acatatacaa aattttagtg
   151441 gagatggtat gattatttct acttccacag gttcaacagc ctataactat tctgctggag
   151501 gtagtattgt tgatataaat cttgaactta tgcagattac acctttacat ccgataaata
   151561 ccaatgcata taggtgcttt acatcaagta taatatgttc aaatgaatct gttataaaga
   151621 ttgcaccaga atatagattt gaagattctg tattgattgt cgttgatgga gttgagcaca
   151681 gatttagaca aatcgaaaat ataaaagtta gtatatctga tgcaaaaata aaattactta
   151741 gaatgtcaaa ctatgagttt tggcatagag tatctgaaaa atttttatag actgtactta
   151801 ggaggatttt taatatgaaa ataggaataa tgagtgatac tcatggtagc ttactttact
   151861 ttgaaaaagc gttaaatgta ttatctgatt gtgatgtttt attacatggt ggagatgtct
   151921 tatatcatgg acctagaaat gatattccag aaggatataa tcctaaaaaa tttattgaga
   151981 cattaaataa attagaaaac attgtgattg taaaagggaa ctgtgatgca gatgttgacc
   152041 agatggttat agaacatcct attcagagtc cttatgtcat gagccaattt ggtgaaatta
   152101 gaattatatt gaatcatggt tatatagaat cagaagaaga aattattgac aaagcaaaga
   152161 aaatgggtgg tgacatatta gttttaggac atactcatgt aaaaaagcta tacatggatg
   152221 ataatttaat agtaataaat ccaggaagta cttctatccc aaaagatgga agccattctg
   152281 tcgcaattat agatatcata aaaactgatg atgaggatga gcttgaactt gatataaact
   152341 taattgacat caatactgga aatataataa atatcaatga ttagtaaatt tttaataaaa
   152401 ataaaataag ctttaattta ttaaactcat aataaaaaca agtaaaccat tttatttcta
   152461 tctcaattag aagtttaagt acaatacctt aaacttctaa ttaaatagaa tctggtttac
   152521 ttgttttatt atatgctata ttgaaatata acttagttta cttgtttcta ttatatatta
   152581 tattggagta taatttagt
//
LOCUS       DAEOTL010000002       133729 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEOTL010000002 DAEOTL010000000
VERSION     DAEOTL010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 133729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 133729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..133729
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.002"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            535..675
                     /locus_tag="KRH82_000187"
     CDS             535..675
                     /locus_tag="KRH82_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653493.1"
                     /translation="MSEGKINKEKLMKLGNMLSELKRNNKDKFTNYKSEVEKYENKKR
                     GA"
     gene            complement(686..1024)
                     /locus_tag="KRH82_000188"
     CDS             complement(686..1024)
                     /locus_tag="KRH82_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653494.1"
                     /translation="MNKRLKTLRKELGLNQTQMGNKLFLSQDHISSLETGRRDLTDRI
                     INDICKEFNVNENWLRTGEGDIFQDPTLDMDFDDDIKEMLRMISKLSPEAQKRLYNVA
                     EVFLEEENKK"
     gene            1187..1342
                     /locus_tag="KRH82_000189"
     CDS             1187..1342
                     /locus_tag="KRH82_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653495.1"
                     /translation="MHKKKMNQKELELLGKMFLKIKKIDKQKFGELKGSVKTSLEYEY
                     ILVNKIR"
     gene            complement(1481..1834)
                     /locus_tag="KRH82_000190"
     CDS             complement(1481..1834)
                     /locus_tag="KRH82_000190"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653496.1"
                     /translation="MNIGKKIKFLINNSGLTLTDISAKTKIPTSTLSDIINGKTKNLS
                     IQKAKLICDVFNCSLDYLLDDEVDEKDINKSDYLNKQLIEKYKLLKYEYKEFVLSQID
                     GLLKIQNDTNSEFKK"
     gene            1995..2189
                     /locus_tag="KRH82_000191"
     CDS             1995..2189
                     /locus_tag="KRH82_000191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653497.1"
                     /translation="MFVNWKIEMIKNNITVKEIANILNKDEELVKSIIDGQQELSIID
                     GVKIREIFFPKLSLDYLYLE"
     gene            2234..3040
                     /locus_tag="KRH82_000192"
     CDS             2234..3040
                     /locus_tag="KRH82_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBG8653498.1"
                     /translation="MNNLNIKGRQKFMDLEIPVIEGGFGEDKKCMTDKTIAEMHNMET
                     KNVRARINSNIARFKKEVDYIDLKVAYEISDNLQILKALGYSNMQISKADNIYLLSER
                     GYSKLIKIMDTDLAWEIHDKIMDEYFNMREHLIDSYMIQDSIERAKRWIEEEKERLLL
                     KETIQVQQPKVEYHDKVLNPDKLVTTTDIAKDLGMTAQALNKLLHLNRIIYPERINGR
                     IKCWKPYKNYLWLIPEYADFKITEHDTQLKWTEIGRKWLIEFVENIKKIS"
     gene            3104..3328
                     /locus_tag="KRH82_000193"
     CDS             3104..3328
                     /locus_tag="KRH82_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653499.1"
                     /translation="MIKQILNKRGSLLNLASEYLTEQDYLKFQGWYTHRYSKLDAYDA
                     SINEYLNYKNDKKLITYVFNLKFQEALIEI"
     gene            3352..3888
                     /locus_tag="KRH82_000194"
     CDS             3352..3888
                     /locus_tag="KRH82_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653500.1"
                     /translation="MNYNYVTKIDLKYGNTQFGFEKYSDALDKYRELKEEFKYVPCII
                     KLHSYVAHQDLYVKEIKADGFEKKYLDIKNLIKLFKEHKQNISDELSLCDKKKEEVLH
                     VIEEMNLDTASLSDKIDTIKELKNTLAKRRLVKYELNKYFAFCNTLYEIEEELKKYES
                     KYKQKENQGKSRFKKNKK"
     gene            3897..4037
                     /locus_tag="KRH82_000195"
     CDS             3897..4037
                     /locus_tag="KRH82_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653501.1"
                     /translation="MEEYQFNLIKKLCAERKIHKAWFRNIEKCGCGGKCNKKNCKMLE
                     KL"
     gene            4048..4281
                     /locus_tag="KRH82_000196"
     CDS             4048..4281
                     /locus_tag="KRH82_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653502.1"
                     /translation="MENQTELTEKDIENTLSALNIIKYICIKSKHCKNCPLGYMKNLD
                     EHNCMLYALIDRGLLPCDWNAKKVTRLLDAIVE"
     gene            4305..4727
                     /locus_tag="KRH82_000197"
     CDS             4305..4727
                     /locus_tag="KRH82_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBG8653503.1"
                     /translation="MIHELKILPKYYEAVSNGSKSFEIRFNDRDFKIGDTLKLQEYID
                     GVYTGRSLQREVSYILNDSNYIKNGYIILGLINNTNHYMFKVVRDYKKENYLICRQGK
                     VFIGYILGNFACCKESLEQFTIPLEYIEKISRVEFKPL"
     gene            4920..5462
                     /locus_tag="KRH82_000198"
     CDS             4920..5462
                     /locus_tag="KRH82_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HBG8653504.1"
                     /translation="MSKKDKLSIFISLILRHKPETIGIKLDDYGYADVNELIEKINNT
                     GRNINIEILEQIVKEDNKQRYSFNDDRSKIRANQGHSINVNVELRELEPPKYLYHGTA
                     TRFLDNIKNEGIIKQSRLYVHLSRDIDIAVKVGKRHGTPVILKINTGKMYENGYKFYL
                     SENNVWLCEYIPFKYVEIFE"
     gene            5512..5880
                     /locus_tag="KRH82_000199"
     CDS             5512..5880
                     /locus_tag="KRH82_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653505.1"
                     /translation="MSRCKDCFYFEKNKIEESGICNKKEKEVYKENRKCEFYESKKWK
                     SMNIDEFWIEMERWTNEKVNRYIIYFSEHDSIQIDIVQDINRPNNPTDDEVIEEYVEN
                     NYGYVKYEVIDLGTVENVKL"
     gene            5900..6676
                     /locus_tag="KRH82_000200"
     CDS             5900..6676
                     /locus_tag="KRH82_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653506.1"
                     /translation="MENIELTPRDYFEDIKNRKQKNTNEKLDIIYENSLILLNKYIVT
                     GQKKGAKKLMFLLECIEKERNVIELGIDTFVYKEDIEKYIDDISKNTVKIIELENYER
                     EIPDEIVEIIEKTKDIFDKMYVLFTDYTGKITKEISKERRDKDPILFGVFSDEKSRAI
                     VDRFYYLGDWEDEYCDLTLEKMINDYKKKGRQDILKHIITPKSLDELKKELDSLEKNN
                     DTYKQLANIKPLPTTKNSSVEPPKLNIFKKIKNRVFKNEK"
     gene            6666..7070
                     /locus_tag="KRH82_000201"
     CDS             6666..7070
                     /locus_tag="KRH82_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653507.1"
                     /translation="MKSNVDLTENRDFRAVRGRGINILGIEDAPNRMLNGFSDFGIGR
                     LYGKNLEFEFNKNEVFLTGNANDREEKKFLILCEENKVCVRCGDELKERWDKVSIELC
                     NKCYEMLDVEYKNKKIIRELFFRDRDVNIELL"
     gene            7108..7497
                     /locus_tag="KRH82_000202"
     CDS             7108..7497
                     /locus_tag="KRH82_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653508.1"
                     /translation="MKDVWLYSWDDECFRSDEYESKEEAVEAAKEELKRLGEIKRWVY
                     IGKKEEADIPDIDAKDALECIQNRIDDEYGEYGEDWFENIRAEDILILESRISEVFKK
                     WIDDFKYKPYWFAVRDIEEIELKNVVN"
     gene            7557..7877
                     /locus_tag="KRH82_000203"
     CDS             7557..7877
                     /locus_tag="KRH82_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653509.1"
                     /translation="MFIKGFRCICRHKFSRIKDCYLITTKSQQHTCKIWVCKYCGQIV
                     AGSTPVYHPNMKVNEYCVKCELLACSNNYEGYCNSKDKEIEFKSICLEGNKEILQCKN
                     FDLE"
     gene            7908..8093
                     /locus_tag="KRH82_000204"
     CDS             7908..8093
                     /locus_tag="KRH82_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653510.1"
                     /translation="MKINVHVKTNKIGSDCKLEFEIDDDDLKDMSDEEREGYIDKIAW
                     DYVFENFIDWNWYEVED"
     gene            8148..8549
                     /locus_tag="KRH82_000205"
     CDS             8148..8549
                     /locus_tag="KRH82_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA ligase"
                     /protein_id="HBG8653511.1"
                     /translation="MKELLEVKKIFDSLASTSSRKEKERILEKYKNNRMFVECLQFLL
                     DSNILTGISKNKICKNLNNTGHNELENIYDMLDYLIKNNTGRNIDVKTIQVFASKDEK
                     LKDFIFNLATKSIKLGITYKTVDKIMPGLII"
     gene            8651..9154
                     /locus_tag="KRH82_000206"
     CDS             8651..9154
                     /locus_tag="KRH82_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653512.1"
                     /translation="MTDKIIIASVDGEEMIFRTEMKKLEKGDSLIVSVNGVKRLALFI
                     RYISTCEEYIEDIAFQKVDEILYENTIAKEKERVKKVFKDKCMKNYKPIVNTEIDSYL
                     RECGFNCDGRQFFKSIDNTQILISRDCDKDVLTVSKGLTITKTDITNKNLITVIKIIN
                     NSLLIVR"
     gene            9214..11439
                     /locus_tag="KRH82_000207"
     CDS             9214..11439
                     /locus_tag="KRH82_000207"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBG8653513.1"
                     /translation="MKNVIKRDGRIVPFDEKKIINAIEKSFLSLRNKGKSEVFDRELA
                     TLIAKKIKNKPCEKMHIEDIQDIIEFSLMASKKKDVAKEYITYREKRNIARGRKTYND
                     YMSIVNTESNDITKENANMNADTPAGMMMKFASEATKTFTDHVLLSEEAKEAMMDNYI
                     HIHDKDYYPTKSLTCIQHPLDKIFNNGFRAGHGSSRPTKRIETSSILGCISLETVQNE
                     MHGGQAIPAFDFYNAPSVRKTFIEEIKNIEIKDDIDLSHLYNIEIEDYIIKDLKELDS
                     EKRNVQHAINRTVWRVHQSMESFIHNMNTIHSRGGNQVVFSSINYGTDTSAEGRCIIR
                     EILKSTYEGVGNGETPIFPIQIWKVKEGVNYNPTDRNYDLYELACKVSAKRFFPNFLN
                     LDATFNKHVKWKMCDPNRYIYEVATMGCRTRVFEDLHGEKTSIGRGNLSFTTLNLVKM
                     ALEAKEKYPNNEANRVAEFIFLLDKYSDVVARQLYDRYLFQCTAKAKQFPLLMSGLWK
                     NSENLNPNDDVSEVLKHGTLGVGFIGLAECLIALIGEHHGESEKAQKLGLEIISLLKS
                     KVEKYKKKYNLNYSVLGTPAEGLSGKFTQKDKKIFGEIKNITDKDYYTNSSHVPVWYN
                     CNVEHKAKIEAPYHELEGGGHIFYVELDGDATHNPKAIMKVVDLMKKYNMGYGSVNHT
                     RSRCMNCGFENADSELKECPKCGSNSINIIQRITGYLVGTTDSWNNAKLAELKDRVTH
                     G"
     gene            11432..11929
                     /gene="nrdG"
                     /locus_tag="KRH82_000208"
     CDS             11432..11929
                     /gene="nrdG"
                     /locus_tag="KRH82_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBG8653514.1"
                     /translation="MDKDYIYILDIKHDTIVDGEGFRTSIYCSGCNHMCRGCHNPQSW
                     DIKNGTLTKVLDIYKEIISNKFSDVTFSGGDPLLQLQGFVHLAKLIKKNTNKTIWCYT
                     GFKFEELITDNEKLELLKLIDVLVDGKFEEDKKSLELIFKGSSNQRIIDVQKTLYEKQ
                     IVLYE"
     gene            12130..12537
                     /locus_tag="KRH82_000209"
     CDS             12130..12537
                     /locus_tag="KRH82_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653515.1"
                     /translation="MYFETDIIKNKNTVNKIIKYCGGNTEKLKDWLKEIENKSISSLE
                     ELKEYPLKRNYKFVFSKEEAPNLDKLIKMKLRDNCLEKCEICSLENLLSMLNDEILDL
                     NKEDISYEDNIEWIENCKEELIKLKVGSICIDW"
     gene            12558..12869
                     /locus_tag="KRH82_000210"
                     /pseudo
     CDS             12558..12869
                     /locus_tag="KRH82_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900673.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12960..13310
                     /gene="tnpA"
                     /locus_tag="KRH82_000211"
                     /pseudo
     CDS             12960..13310
                     /gene="tnpA"
                     /locus_tag="KRH82_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003378761.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            13328..14767
                     /locus_tag="KRH82_000212"
     CDS             13328..14767
                     /locus_tag="KRH82_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015978935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBG8653516.1"
                     /translation="MSNYILTLQLKTEKFQEDIICNAFDKYRKVYNSCLSELFKRYNH
                     MIESKEHQANCKYKGKDRNKIFSEINKKYNLTEYSLHKFVKFIGKYYKLHSAITQKIA
                     TRCFNAFNKYIYHQAKRVNYIRYNELTSIEGKQNSTGISYKDGIIKFNKMTIPVIIKN
                     NDNYAQRAIQDKIKYCRILKKEIKGKIKWYVQLVLEGIPPKKTTNQGKIKGQIGLGNV
                     GIDIGTQTIAISSKCDVKLLELAPNVNNIDRQIKLIQRKMDRSKRATNLNKFNDNGTI
                     KQGNRDKWIFSNHYLKLKRLRKELYRKQAEIRKQDHYILINKLLNLGNKFYVETMSYK
                     RLQTRVKDTTINEKTGRINKKKRFGKSLANKAPSMFLTMLDNKLKYNNERLYKIDTAK
                     CRASQYNHFSDEYNKKELKDRWNNGMDIQRDCYSAFLIMNVNEDLKSINRELCVKTYD
                     NFKILHDKEINRLKKLKLNGYKLISSMGI"
     gene            14968..15192
                     /locus_tag="KRH82_000213"
     CDS             14968..15192
                     /locus_tag="KRH82_000213"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653517.1"
                     /translation="MVIYKNKKKDIIRDESMYDYGMSLSSIMKVILNHQEDIEKLKEE
                     EVAEFIKNKLENEHDCDELKIISEVFNEIY"
     gene            15179..15289
                     /locus_tag="KRH82_000214"
     CDS             15179..15289
                     /locus_tag="KRH82_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBG8653518.1"
                     /translation="MKYIKHVDNGVMRAIGIDNYKPLLNIIKEKVNLESN"
     gene            15318..15785
                     /locus_tag="KRH82_000215"
     CDS             15318..15785
                     /locus_tag="KRH82_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653519.1"
                     /translation="MGLDLGFYSVKTKVTDLDIYLNKTRGEKYKELNNDEEEFYKFEE
                     LLDIDISLEDWSVIRMIYKAKWEKGYESYEDEAILITKEDLEDYIIPFLKQKDINSKI
                     YNKDKEYYYKNDKKVTVDDRYTQEFWDLVLKEFQKMLNIIDFEKHSLIIMYWY"
     gene            15821..16201
                     /locus_tag="KRH82_000216"
     CDS             15821..16201
                     /locus_tag="KRH82_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="HBG8653520.1"
                     /translation="MKKMYIAINSDLNMSPGKVGAQVAHAVYDYLYNKILDTVSCSYE
                     TEIIAHELIDLKCDLTSFKNNGDTICILKAKEAQLLKFKEKGYLTIVDRGLTEIPKNS
                     ITCVNLGIFNEDEIPSTIKRLRLY"
     gene            16217..16372
                     /locus_tag="KRH82_000217"
     CDS             16217..16372
                     /locus_tag="KRH82_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653521.1"
                     /translation="MYSKGDVVKVWCYQCERIEFQEFVGYFNSYFDNYKLKKRWKCSK
                     CDVINNF"
     gene            16399..16845
                     /locus_tag="KRH82_000218"
     CDS             16399..16845
                     /locus_tag="KRH82_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653522.1"
                     /translation="MKIKKIILGLDNLENVELGIGDVGGFYLDNIHEIIGGFALSYIG
                     KCKKADYLHIQIHKRVDEIQRLHDYKDITNVKIEYENGSVEDIYVPYKQEGDFLGLDN
                     LYQTSFISKRGYLHIVISKDKTVEEVFNEEFEDDEGVEFSFNMYGI"
     gene            17123..17287
                     /locus_tag="KRH82_000219"
     CDS             17123..17287
                     /locus_tag="KRH82_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653523.1"
                     /translation="MTDKEMEEYIINLIKDKIKEEYGENRLPEILMEKFIKLERKGSV
                     TVDVQDLIEG"
     gene            17331..18584
                     /locus_tag="KRH82_000220"
     CDS             17331..18584
                     /locus_tag="KRH82_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
                     /protein_id="HBG8653524.1"
                     /translation="MEVQGKYNKAKIFTENVDSITIGQIINLCNQKEFKESSIRIMPD
                     CHAGKGCTIGTTMTISDKVVPNLVGVDIGCGMATIPLEKYINNINYTKLDKIIRDYIP
                     HGFKIHNKSREKLLKNLFNIDINNLRCEVNKNRAYMSLGTLGGGNHFIEVDKSEKGQM
                     YLTVHTGSRNLGKQIADYYQDKAIKYCIEKYKKSYDDAKEFLISTLKKDNKEHLINKY
                     LKDLSDRKLNKPHDDLCYLENDLMEDYLHDMSIAQKYAAANRMVIIADILFKYNSLDV
                     NYDHFIRDIKCDVIECIHNYIDMDSKILRKGAISANKDETVIIPVNMRDGIILGKGKG
                     NSEWNYSAPHGAGRILSRGKAKEKISLDEFEESMKEIFTTCVGQSTLDEAPQAYKPIE
                     DILNNIGDTIEIMEVLKPVYNFKSN"
     gene            18624..19025
                     /locus_tag="KRH82_000221"
     CDS             18624..19025
                     /locus_tag="KRH82_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653525.1"
                     /translation="MGMYTEFVCAIELKKDTPKEVINILNNMIEGEDRYDITPPHPFF
                     ECRRWRWLFIMDSYSFSGRSNTMFEYDDIAKTYYLTIRSNLKNYDDEINKFLNWIKPY
                     IQIHCEDDEFLGYSRYEECRNPELIYYNEIQ"
     gene            19052..19285
                     /locus_tag="KRH82_000222"
     CDS             19052..19285
                     /locus_tag="KRH82_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653526.1"
                     /translation="MKFEDNMIKSFREVRVGDIILAGNNKYLIISILNYFGYVNLDTG
                     DCSSGFRSIEELMKQFDKQTRFIQNDRFKLILD"
     gene            19328..19738
                     /locus_tag="KRH82_000223"
     CDS             19328..19738
                     /locus_tag="KRH82_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653527.1"
                     /translation="MCKFCESIIDNTKDILLTSRSRLLEDNTCEIIAEDNCNNCYDGC
                     YEYFKLNGYKIRGNTYVNVDYYKKIRKIIIAPCSESVHINYCPYCGKQVSKDIKDFNC
                     IPEHIVDVRYKNGDVYDYDMEKSVQEVMDNANNN"
     gene            19769..19942
                     /locus_tag="KRH82_000224"
     CDS             19769..19942
                     /locus_tag="KRH82_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653528.1"
                     /translation="MNLWSKIEEPVMRAVSGIVFNIWGNVCFSIYYIEENKQIELEIY
                     DRPYRYEGKKNSC"
     gene            20052..20195
                     /locus_tag="KRH82_000225"
     CDS             20052..20195
                     /locus_tag="KRH82_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653529.1"
                     /translation="MNKGIKNYITAVNYLLDNLEYMMEDDEFNNEKLQKRIDVIRKFE
                     REL"
     gene            20197..20502
                     /locus_tag="KRH82_000226"
     CDS             20197..20502
                     /locus_tag="KRH82_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653530.1"
                     /translation="MGKIKNGEIDTEDYRLFKNIQKEKDRVYSKYINEEYIMEELINY
                     LRLEDKDYTTEILERYARYIDENLDNRCPYCVYNICSEHDNCFDGILENLKEKIKIK"
     gene            20528..20881
                     /locus_tag="KRH82_000227"
     CDS             20528..20881
                     /locus_tag="KRH82_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653531.1"
                     /translation="MKLINGDRCSGKTTTLIKYAYENNALILCYSCGNLNYIIEKAKE
                     LKLDIIIPRVFKTYIESNHKIEYMKTINGNIINDTSNIRLVIDEIDCCLESIIREGID
                     CVTGTIQIENLNNHI"
     gene            20961..21245
                     /locus_tag="KRH82_000228"
     CDS             20961..21245
                     /locus_tag="KRH82_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5052 family protein"
                     /protein_id="HBG8653532.1"
                     /translation="MKKILLIGALGTMLIGMSGCTGIQSSMKDAESDVSGLNRVVNVY
                     SDNGEVLKTYTSKSMRVKDGDGGTITLDFDGKRVIICNAHVVIEENQSNK"
     gene            21257..21424
                     /locus_tag="KRH82_000229"
     CDS             21257..21424
                     /locus_tag="KRH82_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653533.1"
                     /translation="MFKVLKTILIIIWVVDILNFPQFQFLDTTYPINTLAWLLIWILI
                     PSSSIYIDKKE"
     gene            21602..21754
                     /locus_tag="KRH82_000230"
     CDS             21602..21754
                     /locus_tag="KRH82_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653534.1"
                     /translation="MKITISIEEAMDIIKQHYENKGIEIKDLSFNLEKTGMVRNIKFK
                     GEIILK"
     gene            21802..22404
                     /locus_tag="KRH82_000231"
     CDS             21802..22404
                     /locus_tag="KRH82_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653535.1"
                     /translation="MILISSTNRSNARDFHVSDYYRTPITKIKEFLTEFSRYENILNP
                     NIKILDPCAGGDNTNPMSYPTAIQEFLNQDISIDTVDIRDDSRANIKQDYLKFQPKEK
                     YDVIITNPPFNLSLDIINKALNDVREGGFVIMLLRLNYLGGKVRQRLWGNNMPKYIFV
                     HNRRMSFTDDGKTDSIEYAHFVWQKGYNPKFSQLKVLISQ"
     gene            22419..22628
                     /locus_tag="KRH82_000232"
     CDS             22419..22628
                     /locus_tag="KRH82_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653536.1"
                     /translation="MKVKYVVFEWEITSKNDGQKHFINFRDLIKLYGVSSRECIRAKD
                     YYERDGLDLKDIKFLYPRDDGKYKL"
     gene            22683..22928
                     /locus_tag="KRH82_000233"
     CDS             22683..22928
                     /locus_tag="KRH82_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653537.1"
                     /translation="MDIKIDMCLLEMEINRRRCEYAARTGRYPNSLILWEGYYSLLNI
                     QYIEDKTRGYITKFNGMDVIKCNDFLKIELFEKNINN"
     gene            22957..26028
                     /locus_tag="KRH82_000234"
     CDS             22957..26028
                     /locus_tag="KRH82_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019595671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBG8653538.1"
                     /translation="MRYNNYHSHKIYSNIRSLDVITKPQQYIDRAIKLGQNTYFTTEH
                     GYQGNVYEAKTLCDEYKLKMIIGAEFYYVNDINEKDRGNYHLIVIAKNNDGYKQINKA
                     LSLANKNGYYYKPRIDEKILFEIFKPGDVVITTACVAGILKLENREELILKLKNYFKN
                     NFFLEVQSHPHKTQALHNKDVLELSNKYNIDIIHANDSHYIYPEESKYRTKFLKAKGI
                     NYPEEDGFILDYPNSEDIFKRYEKQNVLTKQEVERALKNTLIFDECEEITLINDDIKL
                     PSISKNPNKELKEILNKEWLEKRKNIPKNRWNEYLDAIRYEFDIIEKTHMEDYFIIDY
                     KIVQRAKQEYNGLLTKTGRGSAPSFIITNLLGLTEIDRLNAPVPLFPTRFMSVERILS
                     AKSLPDIDLNAEDAEPFIQATRDLLGEENCAWMISYKPLQDASAFRLWCKANDMKLSE
                     YDEVAKNLDKYTNDVFWKDVIKESKVFVGVVESVSFSPCSMLIYDRPIDEEVGLLKTK
                     DGVCCNIDGYYCDKYKYLKNDYLTVKVWSLIRKICELANISIPTIEELNILLDAKTYD
                     IYKDKLTCTINQVDSDYATNLASKYKISSVAETSAFVASIRPGFASLLDNFINRESYT
                     TNVKELDILLEDSYHYLMYQESIMKYLIWLGIEESESYDIINKIKKKRFKEKELKELH
                     IKLKNNWIKKVGTENNFEDTWQVVNDAASYSFNASHSLSYAYDSLYCAYLKSHYPLEY
                     YTVAFNLYNEDTERTRKLTDEIEYFSIKLENPKFRFSKSEYFFNRDTNSIYKGIESIK
                     FLNSDIGEYLYSLKDNKYDSFLELLIDLQGHINSKQLSILIKLDFFEEFGKSNKLLET
                     YDIYNSIYSKKQFKRDNLPCNINTMRKYSNKETEKIFKEVDTKELCSYLESQIENTDI
                     PTNEKIQAHFEFVGSCNIKDSNSNPRYCLVIDIDTKYSPKVTLYNISSGNIKIFKVSK
                     PIFEDNKIDVYDLVYLKSIKEKAKSKKVDGKWIRSNTETEWWIQEYWKIEN"
     gene            26131..26382
                     /locus_tag="KRH82_000235"
     CDS             26131..26382
                     /locus_tag="KRH82_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653539.1"
                     /translation="MISILIDEQRYYSLLEEKKDLSMRIDELKEENAFLKQENEEYEE
                     ILNEWECVRKEIVATCKKKEILGEKPSELEMVLQKIEDI"
     gene            26382..26702
                     /locus_tag="KRH82_000236"
     CDS             26382..26702
                     /locus_tag="KRH82_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653540.1"
                     /translation="MSVNKIYEKKEYIIIKSKSGYIVYNTNKEFKEGHTHLKSYNAAK
                     TAIDLVIKRRLPKSYSIYFLTSLMRISNDVQYIKHISDIVYIRNNKGLKEKYINSKNI
                     KKNY"
     gene            26777..27898
                     /locus_tag="KRH82_000237"
     CDS             26777..27898
                     /locus_tag="KRH82_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfJ domain-containing protein"
                     /protein_id="HBG8653541.1"
                     /translation="MKSYKEKQFLVFEFENGKNVKYNLATGEYVGKSGRIVKDVCTQL
                     RGYNLHEVINSFEDENYKCFLNFVDERVNRSKSSRAWGRRVERIRNIGSFLNEINNYS
                     EYEQLFSAGLKKIIYPIHCDIKSIPKGLISICRNYSITLSDRLIQGYSKNPNLYNNLL
                     SLELNSIRKTNLISILDSGYDRMIFDRLIDIYKYKPQSLINYIDNLMTYEALNGLEST
                     LNELYDYVVMMSVISDKYEKYPRHFLTTHKIASRNYNRLKTQFEEEVFNKRIDKSLEY
                     SYQDYKFIYPKNTNEIKDEAVQQNNCVSSYIQNVIDGKCHILFMRKKDNPSKSLVTIE
                     VRNGKIVQAKGKYNRDVNEREQEAIDKYNNRIERMKKIC"
     gene            27892..28323
                     /locus_tag="KRH82_000238"
     CDS             27892..28323
                     /locus_tag="KRH82_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653542.1"
                     /translation="MLIERTKIRLMKEIQGFEMLKIGDIFVITSVGNNGAIHFKTDYG
                     IGFMNYSEFEAYFEIVQQKKKYEWGAWSIRGDFSGAYLYRTNGKKVEVRKGNFKASAT
                     CHDSDEFELNKGVELCLARIEVKKANKQVNLVLDKINNKEI"
     gene            28333..28488
                     /locus_tag="KRH82_000239"
     CDS             28333..28488
                     /locus_tag="KRH82_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653543.1"
                     /translation="MICKFKERCENKNRDCDYCCYNPNAYLEDAFEWNGEGRKPTDEE
                     LDDALEE"
     gene            28533..28760
                     /locus_tag="KRH82_000240"
     CDS             28533..28760
                     /locus_tag="KRH82_000240"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653544.1"
                     /translation="MEGIINRPVFDLNTFFTGSAISYGYRGNSKHNALISSITPFQID
                     VAYISGNKVESDIISLHHVLDGQIEIELLKF"
     gene            28786..29346
                     /locus_tag="KRH82_000241"
     CDS             28786..29346
                     /locus_tag="KRH82_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653545.1"
                     /translation="MRWKNILVTGALIVGSTIHVFANTEDVVNNNINKELIADTARNI
                     NLMYKKEWEQYKNTKEYKLEIKRINLEKELEIKIEKLIPMTWKVSYYTSLNCENSRYG
                     AVTATGEKLRYGFVANNHLKFGTKILVDGNLKVVKDRGSNKYFGNSNAIDVFVPRIKG
                     ESDYKYYKRVNNMGRHYKEGYIIVEG"
     gene            29358..30023
                     /locus_tag="KRH82_000242"
     CDS             29358..30023
                     /locus_tag="KRH82_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653546.1"
                     /translation="MKVNGIKIPGIIDVSNVCVYGIKESIISSGYPMQQQIKDMREVN
                     ISEKDLQRACQLGKSKQGSGHDCFSKGIIVQMDLQWSEYMWRQWDRYHHNDYVSSQSK
                     MHRLTKFNIDDMCNKYVVKNTINFLNELIYDYNNFQELKLTASDEVTLRNGENIRATK
                     ETLWKIIISNCPSGLMLTARVTLNYLQIKSMINQRENHKMEEWRILCDFFKTLPKYKE
                     LMM"
     gene            30069..30962
                     /locus_tag="KRH82_000243"
     CDS             30069..30962
                     /locus_tag="KRH82_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653547.1"
                     /translation="MAEKRINYNQVFVSGEVLDILNIARMNQGTGQEAIRFTLKVETA
                     PNESVNVDYFTSMFKSDGSPNQMFLGIETIANEIKTRAEDGKGDIVRCVCSLDNNLYY
                     KDGEKKERFQISGTFCNREKYDDKGNPIDDKGEVVKSIKASQVWRVYTLIENIEEKED
                     DLGKYLEIKGLINKYGKQGCNMTFRIHNEDMIEGFKSLYKIGDVGLLEGTVKSMVVSK
                     SAGFGSRIKKSAFTFLEIEGGDEPLKDGDKIFSDKNYPFTDKNIEAMREKIKEKDEKE
                     KQRDVDKNGKTIEISDDDVPF"
     gene            31002..31559
                     /locus_tag="KRH82_000244"
     CDS             31002..31559
                     /locus_tag="KRH82_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBG8653548.1"
                     /translation="MEVKEKTMNDGFKKVVNEEIKTYISNLYSDRIDGLKESDSQIEI
                     TKALIAFHLDIESIPKDNTNPFFRSKYANLDTILKAVNPLLAKHDLILMQSAEDAGND
                     KVYIKTKLKHSSGEYIESNSAPFKPAKTNDIQARGALETYLRRYAVQSVLALSFEEDD
                     DGNSLTNKSKGKSEEENSTIKKSRV"
     gene            31620..32171
                     /locus_tag="KRH82_000245"
     CDS             31620..32171
                     /locus_tag="KRH82_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653549.1"
                     /translation="MNCKCRFCKKKLNTNDAYKVEHITSGGNKQNRYYCNEQEYRKEQ
                     QDIYFWKQCQLGIDYIMGYTVINNQKNKMLQEIIKGGYTREELYDCIIEKKDEVIELL
                     NYRKDIEEEYPKLCYVFTILKGSIRDITIKNKQMKYEKENERIYKEVEKSEEYYEIIA
                     PKKVIYNKRQSLFDKVKGVYQDE"
     gene            32212..33738
                     /locus_tag="KRH82_000246"
     CDS             32212..33738
                     /locus_tag="KRH82_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653550.1"
                     /translation="MVLGTMLKSLTLFSEYKISESDFIIDKVKFFFSLGRIMSKTHNE
                     LDEISVAKFVSSNKLKSEYERYGGWNSLSSAMEYGKETNIAAYIDDLAKNNLLIALDK
                     RGFNVIKEMEHNGLKFIPFEIFQSMKCREVEEFYEGLISSCSVNSIKNNMKVENLLLT
                     KDDREKLKQKTEAGTPYNIIFEYTEKEIGLSNNEESKYIYSLPILSNRTNGIGKGGGI
                     NIIAGFSGIGKTTLLFFNYILAMIYRGEKIVIFANEQKSQYFKSMLVSFIAYNIFNYH
                     DLDRNKIDNGDFTDFEEDLMEKIEKFLRDRCFAENLKFIYMEEFEISEILRKSKELVT
                     HQGFTGIAVDTFKSEDSSDAHYTGKLIENSKLLDSFGNKYNVITMLSMQLLTAQENKS
                     SYLSAGDLSEAKAVKNVCGLLKLMRKVVNELELDSTNKKFFLKPYKLKYNKLKKTTER
                     EYIQFDAKDLQKEYRLLFLNKSRRGQDGDVILLRFYGKTGRLEEIGRCEKVYRGQLSY
                     "
     gene            33748..34809
                     /locus_tag="KRH82_000247"
     CDS             33748..34809
                     /locus_tag="KRH82_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653551.1"
                     /translation="MEIKDLTNEQVINFMEYLGSDLSPKSNDRQLIFNTCLCHNGDSY
                     KLFYYTESKTFHCYSSCGHIGSLIDLLIHINKYEFKDAINEIKDFFGISNQPMLRKGF
                     RIKKKVEQIHDIKDIQIELLPTPKKPYVYKTFQQVPIEEWENENISFEVLKTYQVYYN
                     LYENQIVIPHFCWHDRARPVGIRVRNLDEDKAKSFGKYIPLWYDNRCYNHRLSLNLYG
                     LNVNKKSIKNSKKVIVFEGEKSVLQMATMYKNNPSVAICGSNFSREQKKILIDLGIEE
                     LIIAFDRQFKVKDDEEYVIWRDKIYKLVQDIKDVVNISVIWDKYNLLGYKDSPSDKGK
                     TIFEKLLKNRINIENFVKQ"
     gene            34914..35186
                     /locus_tag="KRH82_000248"
     CDS             34914..35186
                     /locus_tag="KRH82_000248"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653552.1"
                     /translation="MIKFLIKNVHMGDKLYCINNIGNYKKGEIYTVSDTSFFGLFHKT
                     KGENCLPIECYFIHLPKKEELESNPKSMTKEEIEDELGYKIKIVSK"
     gene            35207..36058
                     /locus_tag="KRH82_000249"
     CDS             35207..36058
                     /locus_tag="KRH82_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653553.1"
                     /translation="MSIFNKKYGRNVKITEEEPPSPPPKQPIYNRDNIQYDKEMERKL
                     LDIDRLKIELEKEKKIEEERKKVERVKENEGKEWAWVEGYKCTDKNMKCKEFQYELNK
                     AYSMDGDDINIWNWGFHLCLDLGDVFQYYAPNLSNRFFKVKALVKKADKYKYGKEYGE
                     VTLLSGSVLRGHKINKIAAKEIIFLEELTFDKLKLHIQNSFPEVNTKSKWYAICKLGE
                     QEYYHRMFMNQMKKIRFSDTFSQLLFDECRNYCEILEILNKAIAYSKENLSKDMIIYL
                     LMKDIRK"
     gene            36082..36525
                     /locus_tag="KRH82_000250"
     CDS             36082..36525
                     /locus_tag="KRH82_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653554.1"
                     /translation="MDKINKIDLIKLKEMNIYDNYQLKKIASKMILHLRYEIMDFCGC
                     GSPEDISFMIKGVLTAIQNKEKNCNLEYTERCYIFEIEFNNVCGIIGSKNDLIQEFIL
                     NALNSYGLLEHGSSIWGSWLSDYGKQILCAFEIVGDCILDVSYLD"
     gene            36552..37211
                     /locus_tag="KRH82_000251"
     CDS             36552..37211
                     /locus_tag="KRH82_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBG8653555.1"
                     /translation="MIKYVMSDLHGMYDKFISMLEQINFNSNDHLYILGDVLDRGDKS
                     LEIIDYIRKYKNITLLKGNHELMFQESYTDVNSSFLWFYNGGKDTFYDLGMKSYEYKE
                     NFYKYIKNLPYLEIIDNFILVHAGLYLPNNYENLSIEQIIELQEEDICVWDRTILNTN
                     KHIKGYTIIIGHTPTQNIKDYEKAEIYKQEGIINIDCGACFDNGKLACLRLDDMKEFY
                     I"
     gene            37222..37749
                     /gene="yyaC"
                     /locus_tag="KRH82_000252"
     CDS             37222..37749
                     /gene="yyaC"
                     /locus_tag="KRH82_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBG8653556.1"
                     /translation="MDILKISYNNLNAISKISEVLRDIVNEDTLIVCIGSDRVLADSL
                     APMIGSILEKSTIRNKIFGVLGDSIHALNLEQKIQAIKNNYPNSNIIAIDACISKISD
                     KGTIIISNKPVKPGLGVDKKLLEVGDYSIVGIIGRNKYDIYDTSDPELILDLADVISK
                     SLISILLEKEERMIV"
     gene            37746..38000
                     /locus_tag="KRH82_000253"
     CDS             37746..38000
                     /locus_tag="KRH82_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653557.1"
                     /translation="MIQEVRQEILLKNGLILYTGDLVEIKYKSDEDVIEHTCKGKIKE
                     AKELFIKLDTSKKYKTSERMIYSWELKEIKKVDDEDEKDN"
     gene            37984..38241
                     /locus_tag="KRH82_000254"
     CDS             37984..38241
                     /locus_tag="KRH82_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653558.1"
                     /translation="MKKIINSKYRALYLFIFFLIFNLIYSLYFGRNTEIGFYSSTSCI
                     EEYILDIITSIGLFFSMMLAGFDVTENFINSLRDYCEKDAK"
     gene            38252..38461
                     /locus_tag="KRH82_000255"
     CDS             38252..38461
                     /locus_tag="KRH82_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653559.1"
                     /translation="MELKDYISKVELNDMPLTLDNQYMLNEISISEYGKIFAVKDTSG
                     RTSYYTEIEFNKLFRGINSILENII"
     gene            38536..39336
                     /locus_tag="KRH82_000256"
     CDS             38536..39336
                     /locus_tag="KRH82_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBG8653560.1"
                     /translation="MEKELYSFSKLNAFHTCPFQYYLTYVKNLNREQNCYGYYGNELH
                     KLLEELQQRKITNQEAIQKYNEVIEYANLMDYNFPTPNSRINYLECILHYIENFVPIE
                     CDKYYIEEYFEFDINGITMRGYIDLYYVIDDKIYVIDYKSSSKFSKKDLPKKSMQLIL
                     YAMYLKEKYPDKVIEYVAFDMCKYMKNEKGVLIDRNKVDSIDDCERAIVKIKYTKELE
                     KQLIDFVIDTVTQIKQLDSNDESVWCKNDDKSNQFFCKTLCSHYEKNC"
     gene            39388..40509
                     /locus_tag="KRH82_000257"
     CDS             39388..40509
                     /locus_tag="KRH82_000257"
                     /inference="COORDINATES: protein motif:HMM:NF013704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBG8653561.1"
                     /translation="MDNISAMDIFENNYFDSCISDFPYDLAFMNKIWDKYENFYEWNM
                     LRAKKLLRIIKPGGYVLIFGHHRTNHRMKCAFEDVGFKIVEEIVWVYGSGFPKNQDIS
                     KLFNKKDLNDLAEKWNGWKTSGLKPAKEIITVFQKPLEGSYIDNIKKYNCGCMNLDTC
                     RIPISKEDIDMLQKKASKNPTNNYSSQINKIYGKFNEDRASQPNELGRFPSNIIFDNI
                     MGTMLDKQSGIRTAGKSNNNALKDKSGVLTPLKRGTLVPRNDVGGASRFFLNIEEELP
                     FMYSPKATKKEKGDYCKHVTVKPKKLIKWLIKLTTPHNGKTIDITSGSGTHGLCCEEL
                     NKEEKYNLSWVNIELLNTKEEPYIDIANKRISDFVNNQI"
     gene            40543..41373
                     /locus_tag="KRH82_000258"
     CDS             40543..41373
                     /locus_tag="KRH82_000258"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HBG8653562.1"
                     /translation="MSIKFQPVIKWSGSKRSQSEEIVNKFPDIIDTYYEPFIGGGSVM
                     FQLLNSNKKVKRYICSDINEDLISLWNAIKSDTESLCLKYEKLWNELNKDEDIERKKK
                     YYYSIRNSYNSTRKPELFLFLSRTCVNGLIRYNSKNEFNTSLHFSRNGINPKKLKEII
                     YQWSKILNDKNVVFLKQSYEKVYPESNDFIYLDPPYANTKGMYQGTIDYEYFWDWIRT
                     LECKLALSFDGKLGSKDKTYDVPKDIYKTHNYLCSGMSNFKKMKQKQAYVYESLYLNY
                     "
     gene            41406..41789
                     /locus_tag="KRH82_000259"
     CDS             41406..41789
                     /locus_tag="KRH82_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653563.1"
                     /translation="MNIPKQVKVGGLFYKIEETEEPILVNNQLCYGLADYGTETIKLS
                     NNLQSQRVKEATFLHELFHCIFRDRCIESEDEEYLVDVLAKGLHQVIIDNPKIFECKK
                     KVNCNPITYPSIPPDKLESIELRGM"
     gene            41789..42361
                     /locus_tag="KRH82_000260"
     CDS             41789..42361
                     /locus_tag="KRH82_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBG8653564.1"
                     /translation="MNKIFVFLGYSGSGKDSIVTEISKQFNIPILISHTTRPPRGQSE
                     IINKTYHFVDNKFFKKEKNNFIEMRKYIVHDGSTWLYGIHKSELENKKYALTIVDACG
                     YKALEKYFMGTKTKLIPFFINTDENILRKRLINRGDNAKEIERRLADDKLKFNDFLNN
                     ESYIAIPNNTNLINAVEQVKIHMKEGIEWY"
     gene            42352..42846
                     /locus_tag="KRH82_000261"
     CDS             42352..42846
                     /locus_tag="KRH82_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBG8653565.1"
                     /translation="MVLALDISMSSTGWAVINRNKKVLKYGKIVTKKDKFKSEDERMC
                     YICNTIQEIITTHNIQIVLVEDQFTSRNSKTILSLRKLLGAIMRTVKLNNIEIEYMYP
                     VSIRKYLMNNGKAKKEEVAAYIRENIIDIGEYIDRTCKAKTSDIYDAIALGIAYLNKL
                     NTNK"
     gene            42870..43376
                     /locus_tag="KRH82_000262"
     CDS             42870..43376
                     /locus_tag="KRH82_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="HBG8653566.1"
                     /translation="MSINVKIKKLNQNAIVPSYAKEGDSGIDLYTLKDTVIPAKSAVA
                     ISTGISLEIPYGYEMQVRPRSGISLKGMFFTRYVTIYDKVQPKKQIRKIFVAHPTVRL
                     GTVDSGYRGEIKIITYNEEDFDILIPKHTKLAQGVFQQVPRAILKVVDELTSSERGNN
                     GFGSTGIR"
     gene            43385..44044
                     /locus_tag="KRH82_000263"
     CDS             43385..44044
                     /locus_tag="KRH82_000263"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653567.1"
                     /translation="MYTIKDVIDVLKSTRNCNLKCNDCILNKSIVTNKIEKTLCWWLE
                     ETRKSLKLSHSNIEFDKQIEILKEVNDIIFECEDKTCNKCIFGEEVSNLYSSCDILEK
                     ICDELSKKTCKLIEKINYYHDYTYEKLYCLENVKTGEKFAVEENQIKRYNILNTNFGG
                     ANMFKYDDYVNLTNSLELPEEIRNKCVRVVMTLENMQDIMIVHKFKTYVVNEKYIEKV
                     S"
     gene            complement(44132..45442)
                     /locus_tag="KRH82_000264"
     CDS             complement(44132..45442)
                     /locus_tag="KRH82_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBG8653568.1"
                     /translation="MDVLNLPDFEVIDTIINEHDMTVIVKPKKEPTICYECGCTEYYK
                     HGKSTRSVKDLNIFDKHVVIEIHSYRYKCKHCNSTFNQKYKSIDERGKITIRLRKQIE
                     KESLKKPFSSIADEYSVSPTTVKRVFEVYMKELEKNIVYTTPIVLSINGLYLKNSVRT
                     IYIDVVHHKILDIQATRNKTDIKAFLNKFPNKKQIEVIIIDMCKHCKEAIYEELPKVK
                     IIIDRFHVLQLITNALEKERKSFKDTLTIKQRKKLLKDKILLSKNREELKDEQIQNMQ
                     TIFNEFPHLKLVYELKEQFRDIYGCQNKEDAFKIYEKWKLSVPKNMKYYQEVIKTVDS
                     WYLEIFNYFGYRTANTSTESVNNLIKYIEKAGKGYRFEIFRAKILFETIATNKPKYNK
                     LTSTKIVNTIKPFSWDDSYNKEKLIEGFGVNIPQLLEVFKSDRF"
     gene            complement(45445..46287)
                     /locus_tag="KRH82_000265"
     CDS             complement(45445..46287)
                     /locus_tag="KRH82_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653569.1"
                     /translation="MKLDFKPTKVPEIEIQDAAGINYLNRIGTKNSDTHYKITKNRVT
                     FRVKKEDIFVKFLDNGKKELNEKYYLYIEYLKETILKEEVESFEIGFEKANIWADKHL
                     SDFEYLNSLIWDIKEKRQSKILEEENVDTLEKAKTVKFPCFSKYSGEYIYDVMQTDLE
                     HCVAYYAGNLNSKEFNFSSVGVNQLNYNPSSERTKSYNCIKYLLDTFYPHISKNLLAY
                     FKDISLDDAKKIIFTSGKYKGKTAYDVYKENRSYLEWYLQNTKKTIYNIRMITAINLI
                     KECE"
     gene            46738..47850
                     /locus_tag="KRH82_000266"
     CDS             46738..47850
                     /locus_tag="KRH82_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8653570.1"
                     /translation="MNAFIRKRNKNYVVYLEFRDDESGKRKQKNMGAFDKKRDANKRL
                     AEVKDSIYKDSFLVPNEITLAGFLLDFLEKYKDNISASTYKSYIAICKNHINPSIGKY
                     RLQELRNIHIQNYIDDLAGNLNPQTIKVHINVLRLAIKRAYRIKLIKENIIDGIESPR
                     IKKFKNEIYDKEHMLKLLEVAKGTNLELPISLAIGLGLRLSEVLGLTWDNIDFDENTI
                     TVNKITSRLDGSVILKEPKTESSVRKIFAPIELMNLLKNYRLEQNKKLLRSIVRNEYN
                     LLFFDRKGNPIAEDVMSKKFRKFLENNDLPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNINTTLNVYSHVLKEMDKEASDRISENLFKAN"
     gene            48427..48804
                     /locus_tag="KRH82_000267"
     CDS             48427..48804
                     /locus_tag="KRH82_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8653571.1"
                     /translation="MYLRKLSKSELIVMKFIWNLDTKVKSYQIINYMKEKYSWSEKTT
                     LKTLSKLSNKRFIYVQETSQCTYYTISIKEDKYHEFISQKIHKLLGCNSIKSLLASLF
                     QEELTDEKITSLEEWVKNWEEEE"
     gene            complement(48945..50206)
                     /locus_tag="KRH82_000268"
                     /pseudo
     CDS             complement(48945..50206)
                     /locus_tag="KRH82_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895108.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
     gene            complement(50361..50687)
                     /locus_tag="KRH82_000269"
     CDS             complement(50361..50687)
                     /locus_tag="KRH82_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8653572.1"
                     /translation="MSMQKIPQAELKVMKFIWNKNDIVTSKEVMEAMELEYNWKATTT
                     LTLLSRLTIKRFLDSERIKRITHYTILITKEEYKIFETKRFLEEVHSNSIESLISSLE
                     DCYKNK"
     gene            complement(50819..51172)
                     /locus_tag="KRH82_000270"
     CDS             complement(50819..51172)
                     /locus_tag="KRH82_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653573.1"
                     /translation="MLEEDEIYNVIGKRIRNYRRKAGYNQNTLAKKAGLFPAYIGQIE
                     RGESKASLRSIFKIANALEIPLEVLFENIIQNENDVETLSSEAYELIDSLTVKEQKAI
                     IRLIKEIIEYRKFEE"
     gene            complement(51503..52441)
                     /locus_tag="KRH82_000271"
     CDS             complement(51503..52441)
                     /locus_tag="KRH82_000271"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012798.1,HMM:NF024886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8653574.1"
                     /translation="MATFEKRSKRIKIEGNINKNNEKLIKGFLQAKKIAGLSEKTIYV
                     YKCDLYTWAKYLHDEMEDLLIEDCTEDDIMEYISFRMEDNHVNRIKVIFSGISSLYDH
                     LRRKRIVTENPVSLIERPKKGLPVVEKHFLNIEQAKELQDKLSKQDDLQLEVYINFAL
                     STAGRVTATSNLRWDNIDFDNRVCENIKEKGGKIVDFYFSEKVKDLLLKLKEVRKKED
                     IVNDYVFLVKYDKEYHKATSNVLRSWAKKAGKLIDIDNLAPHSLRRSFATIAKANNLP
                     LEDISTILNHESTDTTKIYIKEDKGKISKSKDMIGL"
     gene            complement(52476..52787)
                     /locus_tag="KRH82_000272"
     CDS             complement(52476..52787)
                     /locus_tag="KRH82_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653575.1"
                     /translation="MLSKEMVELLSQYGYTAILLMVLMLWLGKYLEKNRQLEQDDRKK
                     ERAYFSREIKEQRTLFGNTIDKFDDKLDKFAEALNTNNSRLERVETDITKIKDKLETR
                     D"
     gene            complement(52788..53039)
                     /locus_tag="KRH82_000273"
     CDS             complement(52788..53039)
                     /locus_tag="KRH82_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBG8653576.1"
                     /translation="MDIMQFIPENLIMLIGGLYILGTFIKESNIKNKYIPFILLVIAM
                     ISSCLFMKELSIEAVFEGILCWGASIGINQIQVQNRKEK"
     gene            complement(53051..53668)
                     /locus_tag="KRH82_000274"
     CDS             complement(53051..53668)
                     /locus_tag="KRH82_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBG8653577.1"
                     /translation="MNILDKSTATLEQVFSYLDTLKNNSNPPHFLCRAIVPIIYKEAE
                     KKGVNPVIAIAQAFVETGYFNFGRVLNPSYCNVCGLKGNKGGGDLDPTAHTRFNFWED
                     GVSAFIDHLALYAGAKGYPKYSELVGKVEYKVNGTTLDPRHFPYLHGEAKTVESLSGK
                     WCPDMNYGQNIINICNKISSMKVENNDVKLEQIKTKVKELNEILG"
     gene            complement(53680..54495)
                     /locus_tag="KRH82_000275"
     CDS             complement(53680..54495)
                     /locus_tag="KRH82_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8653578.1"
                     /translation="MNIKTLTIHAGHNPDNKIGSGAIGNIKESTEARNVLKELLPLAQ
                     KECKVYDCTCNNGTSQSDILNKIIAKCNSYNTDLNVSIHFNSGGGRGVEVLVYNLNDK
                     ETVEIASRICKKITETYHAKGDKDFKNRGVKEKKTLAFLRRTKAKSILVECCFVDTSD
                     TKKYNAKDMAIDIYEGIFNKSVAGKPQDNKVKYAIVYEGDVDKVIAQLMAMNYKTNEV
                     SVCDLKNYVPGHCENLYVIGGASSKIKTSERFTKLQGDDRWATLHKVLDFIGK"
     gene            complement(54576..54746)
                     /locus_tag="KRH82_000276"
     CDS             complement(54576..54746)
                     /locus_tag="KRH82_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653579.1"
                     /translation="MYSILKRMIEQKNYETREELQTKLDVFYAMNRIKESEYTELTNL
                     LNKEDTLVEPII"
     gene            complement(54772..55098)
                     /locus_tag="KRH82_000277"
     CDS             complement(54772..55098)
                     /locus_tag="KRH82_000277"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653580.1"
                     /translation="MDIEKKIEILIEYGFENDLNNIDNYFIADGKKIFTPVIKNGELI
                     KTGEQVYNEWLELQNNPPKSEPSIEEINADKITILIENQKQQDSLLVDNAYRIAMLEL
                     NTNNVL"
     gene            complement(55113..57014)
                     /locus_tag="KRH82_000278"
     CDS             complement(55113..57014)
                     /locus_tag="KRH82_000278"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653581.1"
                     /translation="MIYKDLLKKVNDIENLKEVDNIKCSTDTGEYTIENSKKGYLTNF
                     NVEGKTLIDLWGKTSSDFSLWKATFVDGKINILTENDIRYSNFFTINYTSYKPDTIYT
                     IIVDVDKNTLPSTSGIYIHSLGEENSVFIPNLTNIAIPGGVIGKFKYTFTTISDLNDC
                     NVVLRSVLDNDTLTSGYEISLKITILEGDYTDINIDYSNELLSVGQRDKIEFLSYQYS
                     GINIFNKNADFKDNYILQYLSGEELISEASNHKYTLDYIEIEPDTEYTFYNCSRNICW
                     YDINKSFITASLNERIIGDKDIFYIARSPKNAKYLRVTIIKDLHDNGNKTIITKGNKY
                     DKKTIPYTLRSLPNGIKDEIVYKNDKYYLIKRCEEHTYTDIGNLNLSHVYDNTLQFMG
                     TLTPQAVVDSLDIAYVLCNNLNGKSRNDFNNNDIEGCSTTGSGDIAFKILKSKLTTQD
                     GNGFSEWIKNNPITIIYQLSKPQEIELTSLNLEQYNNQTKFICNTGIVIPDISFESTQ
                     NLGSHIEVIRNNIKNYNVRIDFPFSINFLNGWQPYLGYASSVGNYCTNNNFVTINATI
                     NGGVTTAGTIIGKIPSKYAPRKNIIVIFQTTDGKYYNGIIRTNGEIEIYYNDITYRSW
                     LYLYVNYLI"
     gene            complement(57042..57224)
                     /locus_tag="KRH82_000279"
     CDS             complement(57042..57224)
                     /locus_tag="KRH82_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653582.1"
                     /translation="MNINNIVVRILAERILNGGLNPLKNRPFELDDVTNEDYRKAVED
                     CIIKESGVVERVETTK"
     gene            complement(57224..57517)
                     /locus_tag="KRH82_000280"
     CDS             complement(57224..57517)
                     /locus_tag="KRH82_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653583.1"
                     /translation="MNRANRIICDQTGKILLQTGEATGDILQHDTITELHCIDVEYGS
                     IDYTKNRIIGINIETKQPILEEIPVFITEEEKRIQELENQILLNENEKVGGIL"
     gene            complement(57534..59216)
                     /locus_tag="KRH82_000281"
     CDS             complement(57534..59216)
                     /locus_tag="KRH82_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653584.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWHTDAK
                     GGYSKGEITLKKQTTLYVYVGESGFASSSTSNNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGGATDIRLVGGAWDNEQGLLSRIIVAGGGGGSYSPYTGGAGGGLAGGTGYSANDRHR
                     PGGTQYQGGIGRVSTENGSFGKGCSAKDSTGEGGGGGWFGGAGMNGVGAGGGGSGYVL
                     TKDSYKPTGYTPTSEYYFDNVVMESGGNTAGAYGYALITLLQALPFLTVSSYNSTQAT
                     FKADHTDPTLLTKIEVFIDDVLKETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNA
                     TAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIEASLNNT
                     LVELSEKIKASFDSGDASIEDLTNKLTQANNTIGQLNSKYKVASGSSVVNSCVNKYGF
                     YHGSDYLFLFPGAIQINGLNFVPNIFFTTFELIDSGYFRKFFVFACRGIFTQDFVITA
                     HYHRLETYLKDFKVEGEVLKLNERDVYMDNRGIQLPCQRQGSSFKWQAIKFI"
     gene            complement(59233..59772)
                     /locus_tag="KRH82_000282"
     CDS             complement(59233..59772)
                     /locus_tag="KRH82_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653585.1"
                     /translation="MLNEDVVKKLKNVPNNTNTEIEKVNTNIETAKTELNTKIDQLIA
                     GGSNVASTQTITIDDWVDDTENGFKATVTHGLLTQRIVVNIIDATTKENVVTNFKIID
                     DNSIEIRSETRSELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFVNLEEK
                     VNGGLSNIATSVNELITYC"
     gene            complement(59852..60175)
                     /locus_tag="KRH82_000283"
     CDS             complement(59852..60175)
                     /locus_tag="KRH82_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653586.1"
                     /translation="MIKIDKEKIEKSRQRKELDDLDSSQKTQDNDITDLMLATAEICE
                     MVLSSQQTSTMSLKNIKLNEGGSSMAAIYVGLIERGLKTIDQVPVKYREEVRKMCEAL
                     EISLS"
     gene            complement(60187..65466)
                     /locus_tag="KRH82_000284"
     CDS             complement(60187..65466)
                     /locus_tag="KRH82_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653587.1"
                     /translation="MKKNKLLQRGSLFGNKEFKIEEFNKNFDTFNVKDIFTDMDSGSV
                     FIIKDDLKLYAAGYNVFGNLGLGNKVSPIRYFSKIDIDNVKYVSSSGTHSLLLKNNGD
                     VYSTGLNTDGELGLGDNIDRNTFTKINISNVKQIACGNGYSMLVTNDNELYVCGNNKF
                     GGIGLGNTSTVNTFTKIDNLSVKEIFAGVSCSYILTLNNEVYSTGTNSYGQLGLNDTT
                     NRNIFTKVNLDNVIKISTAQDAVNFLLENGDVYGCGDNSNGQVGVGGGATVTVLTKLS
                     ISNVKNIESGRYHKFYIANNNDIYVTGANPDGRLGDKINCDRSTYTPRKSSISIKNIS
                     KIKCAHAISFILTSNNELYMTGDNSYSFSYLKRYDKFIYGFEKFEDFDIEECNHIESI
                     DNRLLINKNDERVLDIGLENNFVNISLVKANDTSTFIVVNGNELYAAGYNAYGGLGLG
                     HNRHCYEFTRVPLELEEGVTIKDIYLNLGSYFTFILLSDNTLYSTGYNVFGVLGLGDN
                     INRNTFTKVNISSVDKISVGDNHALLKTTTNELFSTGLNNYGQLGLNDATNRNIFTKV
                     STVTYVNEIIAYSNSSYCIDNSRISYAAGYNVFGELSLNDTSSRSVFVKMRYSRYKTD
                     TTVSDVSNIAEIIPFNNGCLIRTTSNNYYVSGRHNYYSTSIKNSVTDDYYSRFGEFVG
                     SKNSNANEVAVLIDEPKLSKVLVSNYNLCLLLDASDGGYKEIKFTGRPSTFGASSQDK
                     NLGLRSLISSSMPYYNHYLGTDNLLYTTSKTRMESKFEIRGRNAGGQRGDSSYYSNSQ
                     KYTLSNAFFAYNSQVIYASGLRIVIKDYFGNIYCSGVNSHGCFGIKKPYDVRHDGFVN
                     ISKQFSKKYIISNIKEIKSDRQALYILLNNSEGYVCGNNAGNKLGTIKARSEFIKVPI
                     DNIKEFIPSNDCLFILTNNNQVYSIGTNDLGQLGLGDNIDRGTFTKVPIDNVKKVITC
                     YKSSYILTYDNELFSTGSNGYGQLGLGDNINRNTFTKVNISGTIKDIFCGRYVFIILL
                     ENDNIISLMGCGNRNYISSNTNSNSLTKINIEGLTDPSTISNLMLEEGKTIITMKNRI
                     FVTGYNSLGGLGVGTSYNNSSGYIEGYKDLAFNSNIKEVALGEYTIFVLLENGDLYSG
                     GNADDGIGFNESGTVVLKKLTSNIKHIYANGKNAYYIDNDNALYVFGSRQLGQINNYS
                     DVVQKTPVRNCLNVKQVYTQHNGLIVQYTNNKLEGKGNAVVGQVGIFNGHEENQIANT
                     SGDNPSDLSFSNEMSIIRNNYGLLVNKKIFLHNDDSINYRIPFGTNAGNYSTSLPFDN
                     IKKMSLSSTHSILILENGDVYGCGSNQFGELAINKSELTTTSEFIKINLTNIIDIACG
                     DNFTYFLKNDGSLFSIGKNSEYQLGIGHNDEVNELQEVLTISNIREIYAYSNYILAIT
                     TEGQLYVQGYNINGILGLNENTKNTIIKLFTKVLENVKYIKSYDDKHIFVIKNDKTLY
                     VTGINKETYKIKDVEIGSMLYTFSQIYIPRDVNDIVDALIKDETLYIISKVDSEKTCL
                     EIKNKSYSSIEIDLQNPNNELTKIEMFINNISSSIIEDLSTGTVTFEINPENLVLGEN
                     KIVFKAHSDIGNNLYINVYIYKKETGATIVKDSTVLIDGNTYNVSSIVDNSQDVVLTL
                     NKGLLEDLNSNNPIYHLVNKLKVQLKINESDTFKDMVKVETRKTENGYKEIYELKDMN
                     IQSAQPKVIVEEGNTNTTIKKPSMLFNLDVETL"
     gene            complement(65477..67555)
                     /locus_tag="KRH82_000285"
     CDS             complement(65477..67555)
                     /locus_tag="KRH82_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBG8653588.1"
                     /translation="MKNYEIKNHTIEVDFSNYRINKRLLDYFIYNENDVKTAYIEAIL
                     KNKDEIIDLSEYDRVLVSITKSDGQKVNGECEVVDAENGVVEIELSRQALASVGINTF
                     QLSLVKDGTLLNTTNLYYRVEEGMINDDDITSTDEYGVLLVIIAQAEEIIKNNKELTK
                     RVEQLEITILGNEEVRDKAEQIRIYNEDIRNIQEEEREFNELTRQNQEANREESIQNM
                     QIQVDDKLTDCQLQLDEMIDAKSEEIDNIVDDKMLDVQAQTDKKFQDLDTRANNTFDL
                     YDKTFEDKLTDNQEQIDYKLDEVNQAISNVEDCIDESTTKLDTKIKEVDDKIVEVNTA
                     KTDMTTTVSNKITEFENRFEELESLDARGELIQARESVDGTVKDTLKDRLTYDFEKVN
                     EKIAEMTSAATNVAFSKSYVESDWVADGEYFKLIVNHNLVTENIFVAILDEATKKSMT
                     NSYTTVDSNTIEIFNESNIDVKVTVVNGNTNKEVIQATINDNITTLDSTYSSIKIDAK
                     FDESLTKINENKSNIATNLEKINLIQSKVGSSELSTVSKNISDAVNELDASVKVLESG
                     GNTNEQLKILKENYNKMSVEILKILFELELDKEATADEAGYWYDTLYDSKNISNLDGL
                     KLNKFKQQLELLSNSGTVLFKNVTVPFLCNKIRYIHDLGSNYSETKTEESYQKGDTEI
                     KINKYSYEVR"
     gene            complement(67567..67722)
                     /locus_tag="KRH82_000286"
     CDS             complement(67567..67722)
                     /locus_tag="KRH82_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653589.1"
                     /translation="MEVNLQKAYTVAFEEIKSLYNELILYKALNMQQQEEIENLKKEL
                     EEQNKEQ"
     gene            complement(67724..69646)
                     /locus_tag="KRH82_000287"
     CDS             complement(67724..69646)
                     /locus_tag="KRH82_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBG8653590.1"
                     /translation="MILDNSPADSWIRITGVIVTYNNTLYQVVDTETNKKYIYWDADN
                     PGTLKVSNVRLPEGNTQFLVVVNDNGKHTEVPINSSIFDISFDGNSRKNTEEQIWGLY
                     ETDEKHNEKFVVIEKDIDGIHQTVLEVQEDASHIKENMSLIDQRAENVNILVKEVTKN
                     FGGSQENITLRENINKAIIKLNADLGTFSSNMSNYFNDNEVTDEEKEKIDIELNLLDT
                     DKASLYTELQKLIDRTTGVDLVAINTSKTALDAASTNLNSIINSVISDSIITPSDRIL
                     AINANAQYNLKINELKNTVDKIYITGMGGSISEEFSQINATAKEIKLEVAKVDGATKT
                     NAAEIKLTKDDITMMVTRNNSGSIVGIKPDKIEFGFNDISNYVEISRSGLTVNQGAIA
                     CDILTTPSGHEPIIRLFGSSRSGFAIDARQSDGSSQASAIRLKYDSNNYFWVGYDTAE
                     IYVDGEEHFIVERDDTFVRCGGATFTFTNGDSLGVGYSFYPERSVTDLGCERYKWRYL
                     YARSTLSESDKKFKENIVYIKDIKNRTRSSITPTPFLDFIRDDFKPATFDYIAEKDRT
                     IADSQIGFIANDFKDSYVGKTFLYDYGEENGLMFSPSGYTTVVATALQEEIQKREELE
                     MIINELNEKINNLGGC"
     gene            complement(69648..71363)
                     /locus_tag="KRH82_000288"
     CDS             complement(69648..71363)
                     /locus_tag="KRH82_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653591.1"
                     /translation="MHFNVNLKQIKSDYTLTIHKMNKSFLGQIPINFLNSIKRELGGV
                     DEIQLTIPKYITDRFLFNKIINPIFEEVKEERLICLNNKEYFVVKNVVTTDDKLKVVT
                     AKSKEVKLGKIDVNIEDYGLQMFTKDEEASIISLNDYLKQETGWKLGYVDDSIAYETD
                     SEGNKREKVRWQESINSNWLDYFNNELKEQFECIADFDTYNNLVNLYHIDSFGDNIQL
                     YLSHDNYIKSLERTTNSDDIVTRLKLEGSEDMDIIGATVTGYDYIENYSYFLDNKEMS
                     EELSRAIKKYQEMNEIREPIWRELIDTKLKKQRERDSKSNEWLHVIETIKAKKDIKKT
                     YDNPEHKDEVNSAKLAVEISELEDKKVILDVQIKHLEEEIAKLDESIKDINILCKRET
                     STDEDGYLIFNEALLDELNEFLYYDTYTNDAFLKVEDLIAEGKRQLSLKCIPTKEWTL
                     DVINFLDRIIDINFRQHWKGDLSLGDIIVLHSKESKEEELVYFTSFTQNLKNGKLDTL
                     ELTLSNKKIKEDDKRTIADYLTKAEHATRTLNSKRHLFIQQQKKRINLPDEYIPKKNI
                     QKELM"
     gene            complement(71695..71850)
                     /locus_tag="KRH82_000289"
     CDS             complement(71695..71850)
                     /locus_tag="KRH82_000289"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653592.1"
                     /translation="MINNIEDCKLLIETEIRMKGIDEKELISQNEILKDLNINEKDLE
                     DIEVNFE"
     gene            72110..72271
                     /locus_tag="KRH82_000290"
     CDS             72110..72271
                     /locus_tag="KRH82_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653593.1"
                     /translation="MEYLVLFLIMIIMITRIINHLTKLIDAILNLKASIRKLKNHQTG
                     GSSDSESNT"
     gene            72633..72812
                     /locus_tag="KRH82_000291"
     CDS             72633..72812
                     /locus_tag="KRH82_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653594.1"
                     /translation="MKYLICLLTIITFLTTIIISLIKLVQNLNRLFKEIDEFKKTLQK
                     IKNHPNGNSGDSSSN"
     gene            complement(73004..74770)
                     /locus_tag="KRH82_000292"
     CDS             complement(73004..74770)
                     /locus_tag="KRH82_000292"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653595.1"
                     /translation="MSDRISLLDKKMKYASGKDKLKYLEEQNALYKEELTLLDQKDKA
                     LNTQKNRLKDRLKKDYKYTFSDDDNLTSYEEKLISLEKELEKLDKQSESDKGSKKSEE
                     RKKKIEEEKKVVEEYLKIAFTEIPKVADAQQEVTNSLIESTRAAEEFKKELKEIAREA
                     ALTSAQKHVTEIQNEIDLIDILMKNAEGDEKLDLIEKKKELLAKQAKEIKDVIKVYED
                     TAKELREGLSKEGFKFSADGKSITNYEQQLAFLKNNKDADKYKEIAENAKKYLDLLLK
                     DLPDANKQIQQNKEEIEDLNKEIQDAYKDQLKEAQSLQEKIRDMYKKELEERLKEIDK
                     ETKAKIDSLKKQQDAYNDSRKEAKYKDDYEEQQDVISDLEKQIAIAERDSSLSGQKKL
                     KDLQKQLKEEQKKLQDLVQDHVDDQVNDMYDKESDRLQEEADKLKEELEKKYSDENLV
                     DLINEAISSGKFVGLDGEVKKLQDAIIEYINKYENGMLAMGSVTKQEWLDKLKEGKET
                     LEDINDILDELDLSKFAMPNYNPSSNSRSRSVSPTSSVNFNSPFFVVQGNVTKDTMKD
                     LEKFGRDLENRVYRKIVENIKS"
     gene            complement(74952..76145)
                     /locus_tag="KRH82_000293"
     CDS             complement(74952..76145)
                     /locus_tag="KRH82_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015395202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBG8653596.1"
                     /translation="MIKAIKVRLYPTKRQEELMFKSAGIARFSYNWGLAFLNKYYEEN
                     NKTLSIGELRKEFTNIRNDEEFSWLKEVSSEIPQQALKDLGESFKKFFRKESSFPRFK
                     KKGKCEVSFFHLNNKFIVKDKYIKLEKIGYVKMKDEGRLPIGNYKKDKIKVLNPRIKF
                     NGRFWYLSLALEVEDKAYTDLKDESIGVDLGIKDLAIVSNIDNPFKNINKSKEVKRLN
                     KKLKRLQKQVSRKYDMLKSGNTFKKGEKFSKTQNIIKIEKQIKIVHKKIADIRLNHIH
                     QTTNTIVKTKPCRVVVEDLNVKGMMKNKHLSKAISEQCFNKFIAILEYKCKWNGIEFV
                     KADRFYPSSKICSCCGTIKKDLRLKDRTYICSNPKCNLVIDRDKNASINLANYKSNHQ
                     HDYLN"
     gene            complement(76138..76746)
                     /locus_tag="KRH82_000294"
     CDS             complement(76138..76746)
                     /locus_tag="KRH82_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
                     /protein_id="HBG8653597.1"
                     /translation="MKRYSIGQFAKKINKTQQTLRNWDKSGKLKPEIVDEKTGYRYYT
                     EKQVKEFYGEVTNKERIVVGYCRVSSAKQKEALERQVENVRTYLISKGYQFKIITDIG
                     SGINYDKKGLNQLIQMILQDEVSKVVLLYKDRLVRFGFELIENICEFKSVDLEVIDNT
                     EKSEEQEIVEDLIQIITVFSCRLQGKRAKKTKDMIKELIDND"
     gene            complement(77239..82026)
                     /locus_tag="KRH82_000295"
     CDS             complement(77239..82026)
                     /locus_tag="KRH82_000295"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653598.1"
                     /translation="MSGIKASASTGEISLNKTAKTLQETAKINVLDKQTGQVRDMMSI
                     LDELAEKWHSVGEDALTKNQKSGIAEAISGKNHINTFFAIMDNWSQTKKFQNDFLNGE
                     VFGSAEKENERFINSAEGKIIKLKESLKQLVTDTISTDMFKTSLDGLSGITGILNGIT
                     KAADKMHISLPLAIGTLSSLFMTIKALGTGKSVPNLLGGLKESFKYPTRSFSKDFQKN
                     IKEFKEVIVGKDGRLKDVTIASKGYALSATAMNKAIKKGVPNLKNTSLETAKLSKHYK
                     ELGISSNQTALANGKISKSYKDLVQKNREISGSNKAIISSNEKLLASSGKVEKATRQA
                     KKSNLLMNSGLANFGKGIASTVGNSLVLTAAFAGISLLTQAMENYANREENAYQARKK
                     NVQASKQQINSYESQKVQLQALAEEYDNLSKKENKSKEDNNRLNELKQQIAKIKPDTV
                     IGTDENGIPILKGQVTDLIAEIDRAINAKERLMSYDKHDNAKTAAKKLNSPSKDVNKT
                     LEERMRESETGKLVKIEEDYTAEVEKNKKRQEKAIEKYNNSTGRARDKARNELMSAKA
                     EEEKIYFKYDEMYRNQVDKIQGYSKEIGDGIFSNIKNKTLYSGLEGNDKSNFAGLESL
                     FDFSEVTPDTLVDTEQAVNKLLTAVRSGKVDVGDLSKTLKDANEEFARTQDIEKYNQT
                     IDKTAKSIAKATNTDANIWENLFGQVNPNGIKDMTSINTLLAKFGKTKLDLANGDKLA
                     MQLQNQFDSIQNILDTTTITGDVKVDANILTDIKNTKEVPSQVKGMIDALLGTGASST
                     DVLKFTMDVLMELQTGDPDITKLQNDLDNKFGKGKFTITPEILLSNDSGQANAEQIIS
                     SLKQRYEELPEEVITVIKANPTATLEEADSVKRIYDKFPKEVKTIIKEEGADEGGRKI
                     LDLTSKYAEVPSELKTKLEADGVGLEKAVEVSEIYKKVPAELKTYFIAEAGEALYNSV
                     NLKDALEHIPDEKITEIYLKQNDGKLGVQDLITSLDKIPLDKDVRINIYKALSDGDID
                     ALGKAIESLPPDKRVEIIAEIEKAKDDIETISSSEIANKIFTIEVKDLASGAIEWIQK
                     KLKEINGDKDKKDPVKEAKESTKKVLKDKPNPKSVAFSRDKEAEKLVDDILNTPPTKQ
                     IELKLKKNEELRNTLNSFKQLEGRNDVKLKLESSGIETEQVKIFADIVKNLPTNSTFT
                     NKFITDNVDSLKNLKDYEAVQKWLMDNPTIAMDYSINLNGLDDFDKMKSIYDGLEDKK
                     DKKVFAEVIIKNPEKAEAFQKLYDNVPEETKSKVVSFAVENADELERATKLYESTPDE
                     QKNQVLNFMLNNEDKLYLIEQLYNDFPESKDIIANLIVNNPDALDEVENLNALDLDKD
                     VKINIIKSLTNGDINSLIAEIEKLPPEKQVEVIAAIEGAIEGIDSVDKKTIKDKWAKL
                     KANNSAALETIRQTENKKLSDKSFTITAHLRTVGTLGGIASQFANNILGGLKSNRKSV
                     QSINSIETTQAIPANLSAQPRTSEPVPISDETPVTKPSLFSRAVSRATSPVKTLTEKF
                     SRITKTPKIALDTKSIDAAVKYSIELLKELENAISKVTVTNSL"
     gene            complement(82611..84236)
                     /locus_tag="KRH82_000296"
     CDS             complement(82611..84236)
                     /locus_tag="KRH82_000296"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBG8653599.1"
                     /translation="MAEEFKIKTSIELDDKKARKQLASLKTSAKENNIKLNVEMNTSS
                     LNNLKQLENTLKQINKLSRETQNGLFGGKGNSNGNINKLTSQYDNFRKKIESTQRQLK
                     KFTQTNILDNKQIGEINKLSGELKRLSNIKLGGLNSKALSDLSNVQSKLANMKIPDMN
                     TKMASQFKTLQNEAGKLANKIETLGKSGYADTSKLQALSNSLKSIQNLNLKNLTSNQI
                     QSEIQKLEQLKNKVKEVENATKNTKLDAKFNMNLSKVISDLNRLRQKCLELGQSTAGI
                     DKLEKELMQLNGMPLGQKVKELDSIKSRLSNMKSNFTGLGTSVKATSGFFSDLYNSMR
                     TYTLGNMIGMSITNGVRNIKTTIVELDSALRDMMKVAPNNFEGTSEQLKNVKNEAISI
                     GKDTARASEDIIQGASKALQTGVKSVSDSLKIAKQSAVFANVGDLDQETADKYLTSVM
                     SAYGGMTKALKPIKDTRVQIKGMSKDYDNLTKFLDLSNYAGNNFAITTGDVGAALQRS
                     ASMLSSAGVSMEDSVALIIGGNESVQNAKLLAC"
     gene            complement(84296..85042)
                     /locus_tag="KRH82_000297"
     CDS             complement(84296..85042)
                     /locus_tag="KRH82_000297"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBG8653600.1"
                     /translation="MFDSEYSFFLILIIGIVIFIFFNFIFKCVKEKEKKEEEEKRTAR
                     IRAEVEEERNRPKDAPLTTRQIISKAVDLSKDAFEGNEGSRDIILTSDNRLVFKARNR
                     SSVLIKKLDDLLQIKLDIQIREKNVMKVISILPTYDKHTMVEKISLKFIFANSTEEIF
                     IIPEYKNITNPIIQYDIDEMERFKLVVENEVEKFKNAKSENNSDIKKDDDDISKISNS
                     LKELQSLKDQEILTEEEFNEKKKVLLEKIK"
     gene            complement(85141..86214)
                     /locus_tag="KRH82_000298"
     CDS             complement(85141..86214)
                     /locus_tag="KRH82_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein/antirepressor Ant"
                     /protein_id="HBG8653601.1"
                     /translation="MGIINRENVNEIMSFEESELSKKFEGMDVEIIELNGELLFELYS
                     TGAALGYTRNNPSGGKRYLQIRRDRIDNVIEKAEIKPLDRSGTKYLTEPQLYDFMLEA
                     KTAKCRPFKKWVTNEVLPTIRKHGAYMTNEALEKAINDPDWTIQLLTELKKERATKEK
                     LRVEQEKNKPKLELANAIESSSSSILIAQLSKILNQNGVDIGQNRLFEWMRNNEYLIR
                     KKRADHNTPTQKSMDLKVLEVSESTGVDKDGNTIVRYTPIVTGKGQIYFLNKILKENS
                     QVLKRFMINNDYIKGVMVEIGKTYAIYDHEYYGFIGILKSVRNEKIRVEEIGDISRSR
                     DIPICMIDYIEEASKEDINKYLK"
     gene            complement(86337..86513)
                     /locus_tag="KRH82_000299"
     CDS             complement(86337..86513)
                     /locus_tag="KRH82_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009244644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653602.1"
                     /translation="MTPRTGRPPSDNPKKNEYRIRMSDDELEILNHCCKELKLTKADV
                     VRLGIKKVYDELEK"
     gene            86816..87265
                     /locus_tag="KRH82_000300"
     CDS             86816..87265
                     /locus_tag="KRH82_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653603.1"
                     /translation="MIGEKLKQLRIKNNLKQSDLARILDVTQGAVGMYENDKRTPSPE
                     LIVKLAEYFNVTTDYLLGHTKTNYSVSANIPGMPSIVCEDNSIYDILDGKKDIKSLKD
                     MNKFLENTDYNNEVKEVLKKYMQLDEMDRKAIERMIDNAYERLKEDN"
     gene            complement(87600..87758)
                     /locus_tag="KRH82_000301"
     CDS             complement(87600..87758)
                     /locus_tag="KRH82_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653604.1"
                     /translation="MSQHKIKPIQATPELSGKDAELFIRQVFSKPSQKEIERNERLLN
                     IITSCRTL"
     gene            complement(88674..89114)
                     /locus_tag="KRH82_000302"
     CDS             complement(88674..89114)
                     /locus_tag="KRH82_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653605.1"
                     /translation="MVFKSLDELVAYTKNKIAASMPEVGKEMKEIMKEEVNKQVYSGY
                     TPVGEWNPNVWGGRTGQLLDAIDVTELSSNSVTSEIQNNGNWVDAFTRNSAFPMERLE
                     KGKVWGVGGYRPQTNIMEESNSKAQERVPKCFKSKMNELGVPVK"
     gene            complement(89115..89573)
                     /locus_tag="KRH82_000303"
     CDS             complement(89115..89573)
                     /locus_tag="KRH82_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653606.1"
                     /translation="MGKIQVDKLIQDEVRAIIPIIDENGKEEYIEVRNPDKETKEEIL
                     NKIWVGMENPDLALSQEDILKMLIDKLTNIELNIEIEDLVDSNISSELETVMYHICQI
                     GNELTASLLMNTDVKLGQMKNEILQDRVLKEIEETEEIEKMNNIKDKVVN"
     gene            complement(89587..90372)
                     /locus_tag="KRH82_000304"
     CDS             complement(89587..90372)
                     /locus_tag="KRH82_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653607.1"
                     /translation="MVFLDDKFLFDNISSESMNIKLVTLGDDEILNEYGLPYEEAIKS
                     DSSFNKNPCYSEDETTIEPITLQFCLCSEHGEAYEWDDYTLENICNWFWQREFKPFIS
                     YDNIEEIYYFKARKIIKRYTKDKKGVLEIEFQPYTNYAYRSFQKVITVKDTREIKLNN
                     VSNVDEEYAPVIDIECLKEGDITIRNSTISDNEEDSLVISGLELNEKITIDNLYYTVL
                     NSTGENRFNIVNRKWIRLRRGVNILKFTGNCKVSIKCKYPIIK"
     gene            complement(90471..91289)
                     /locus_tag="KRH82_000305"
     CDS             complement(90471..91289)
                     /locus_tag="KRH82_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653608.1"
                     /translation="MKRFAVKDAGNVIVKDKVTGEVLFYSQDLNAFNFKLDSESVYAK
                     AKGANTIAFDGAITASLTMEQEVIQMAQLAMLLSSDIDEKTAKVGKRKVLTSDSTKKV
                     TLENIKPVANSISVYSIESDGISIIKKLQFTSSVTGANTEITISTADFNAGDKVAVFY
                     LEEIPKAKVVKIKEESTAPNYVVEAEVMVKTVDGEYMVLYMSVPNAKAQRSIELNLTA
                     ENPSGFNMTLDVLPDENKEYATFTFIGDENLNPARMASMLGVELEDEKDTKPKK"
     gene            complement(91336..92139)
                     /locus_tag="KRH82_000306"
     CDS             complement(91336..92139)
                     /locus_tag="KRH82_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653609.1"
                     /translation="MLENYYITGLPIKLSETLGTVYQPIIEELIKFDMANLEIVNPFL
                     VLEKSYSQLCNEESFELKCKYDAIPILDLMMLTSRKDSSEEIELLSDKIKKSLSILYK
                     TDIKNIEYMNKIKIGILIKFDDKKKNAFISREDFGLVSDLILEMFYIDKKNLFKDEED
                     KWIENTGSEREKQLIAHFKEKERKKREKEAYHLCDYINIVQNIDGYISMDVILKMTYW
                     QLINAYKTKIQFKNYDESLGFAWSFKYQTDMDKMKHWSKEIKIPLSTVK"
     gene            complement(92139..92633)
                     /locus_tag="KRH82_000307"
     CDS             complement(92139..92633)
                     /locus_tag="KRH82_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653610.1"
                     /translation="MAFPNKMISNIGTTLMSNQDFAKFMIYNDESQKDILSMPDVKNP
                     VKELKNKKVFLNRRVEKVLKDADISVFIIMAEYRPCTTGSREIKKTKIEIGVVCHDEC
                     QNTANGLRDVALVCCIVDIITQNEEIAGIGKIKLENVYQMYNLNTDYNGFVITVSSES
                     FGDM"
     gene            complement(92648..93637)
                     /locus_tag="KRH82_000308"
     CDS             complement(92648..93637)
                     /locus_tag="KRH82_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653611.1"
                     /translation="MSYLSDTKKRIGLGCSTPKEKRILQLRLSFKKYLKETPTCIEVP
                     ITDIDEICITEDTKRAIVAINDITNNDKRALDEKNLLVESDLDVDVGCYLFYDNCYWL
                     TIFKEHKEMDTYKHFIIKRCNQFFNYKYKGQMYKIPIAVENLTLYSDGMADNKYTSIS
                     DTKRQLYFGSNPVTKTIDIDTRIMLTGKTVFRVTSINDFEYNGRETGADGLIKAICLQ
                     DALISKDDTINNVAWNDLSENDSVIIPFSKIIGDGFINLGEENEYRIDHSKGVKWLLD
                     KQYRYCNIINQDEKKCVIQANILAKYSGLEVLLLAKDKETNETIDTKKITLRG"
     gene            complement(93639..94268)
                     /locus_tag="KRH82_000309"
     CDS             complement(93639..94268)
                     /locus_tag="KRH82_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653612.1"
                     /translation="MGTPLVKIYKKFLDGINDEEMLLLSNEIIEKMMYSYLEDAIVDF
                     NQCKKDLTIKYVDEKGGEIIPAAQLSYTSNYSNKNAEITLMGKDTKEEYELDKDYTIS
                     FEDEKFIISFVVETTEEIIFKYKYLGEIVSDLDLDEIKILSYGMQIHWLQPKINREEN
                     LKQMLTDSDYNAKSGANMLAKLQAREEQLRTRFNKYQQRYMLKNFEGWN"
     gene            complement(94283..94915)
                     /locus_tag="KRH82_000310"
     CDS             complement(94283..94915)
                     /locus_tag="KRH82_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653613.1"
                     /translation="MARAKKENISKTEVKANTLEKDIKSTLNKKEARLNRLELQRKLK
                     QKKQEIDIEIKNISTWDVDYIDPREKQQIFSLSKVGSKDSTEFIDLDTLYRIVRRSPG
                     FFEEHRLIISDVDSLDVECTPMDIIDFLGLNSLYEYIRNPNEDYLEYFLSDKVDINSF
                     EKILNKNNVELTRRLAERAIDLHKKKKFDSGLKAKLLAKRIGMEDLYLFS"
     gene            complement(94969..95979)
                     /locus_tag="KRH82_000311"
     CDS             complement(94969..95979)
                     /locus_tag="KRH82_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653614.1"
                     /translation="MATAKTLKRIAHELYTDTFREYTDRDGNTITYRDAESAIKNKLK
                     EMMGGEKYNYYKFQENKWGFYNLISELISDDINRLNEEVFSPFCDFENFDLGDKKEFT
                     VENTNLFKVANIADGVNSTRRQRLLNKKVPTTAFKLSVAIYEEAERFITGRINWVVFV
                     NRVSDSYHYDIARRIAKTFEGAYSTINAKFQATGNSDKVLLELIAKVEGATGKKPIIY
                     GTPLALSNLEGVQTDLEKEEKRKYGFIQTFRGGYKVLSLPNAYDENAAEGKEWALDNK
                     AIYVIPDGEKIIKLGTEGDVLVIENTDEKERDDQQIEYFMAQKIHLGVVTAAKFGVYK
                     IQ"
     gene            complement(96067..96564)
                     /locus_tag="KRH82_000312"
     CDS             complement(96067..96564)
                     /locus_tag="KRH82_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653615.1"
                     /translation="MKKDKAIIQTDKVKNPDVLTGKYVVPSEDTNPINLENGAVINIG
                     ELEDTEYGRDTHKIYKVTNDTLDWGIVDDPATMYDERLDERDYEVSPGQICRCRRLKK
                     GDEVTISLLHIADKSIAVKDKLQLKSDSFQFEKLPTADAKTPVAEVLELWNYEGQDSV
                     TIKVL"
     gene            complement(96579..98012)
                     /locus_tag="KRH82_000313"
     CDS             complement(96579..98012)
                     /locus_tag="KRH82_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653616.1"
                     /translation="MKKIKILKLPCNLKHYSDKKKLEELNSNLLPVYIYVMHEGTNPN
                     GTKFYEEAIDKAEPTLKNVPILGYVKINEDGKYDFDGHNVLTQVVQTDEGFILEEYYE
                     ERIIGVIPETNKYEKVEIDGQKYVKCKGYIYKSYSNHAYDIIMDSDEIEISMEIDIND
                     YQLDDSDGFYNIKDYVYHGITCLGSDVKGAMGSNCCLTKFSRKINYKEEISKICSEIY
                     ALEHGEGEKNLPNKNQKLNKNSEGYALAVSNLSTEIRNKLKEYKVETENWYGEKVEVQ
                     AFYYNDLIPEENIAIVEDEINWGYYYGIPYIVNEDAVILDYENKKSYIQTWREKQEGE
                     IVQVFSRQEKLKKEIIEKFTEKQKEISNLKASLEPLQAFKEEKEFELFKSKVDDVAQK
                     FKLAEDEIKDIKIKAYNKEITLDEYKKELGYIFALKTLSNKQSEKENFSINDDKNNTI
                     KIPISNNNDSFSEPEEISFIKKYSDKE"
     gene            complement(98019..98210)
                     /locus_tag="KRH82_000314"
     CDS             complement(98019..98210)
                     /locus_tag="KRH82_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653617.1"
                     /translation="MSKFIYAFSEDDKKLLMEKGYRFICENKLNNKTLYVFENKSKLI
                     NNFSNEEMKRFIFTSKIRF"
     gene            complement(98213..99691)
                     /locus_tag="KRH82_000315"
     CDS             complement(98213..99691)
                     /locus_tag="KRH82_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653618.1"
                     /translation="MGKKNNNKSKSKDNNSTQNQINMLNAQIGKYASVKESTTLATEM
                     YKLRSISRDKLRKALSNPYQISNTDILQDASMILKATSGTYRRVLNLISNMNTFDHIL
                     YPKDISRLKTKEKITKAYMNSASQLEKYNIKFTSAWITEKVLELGEVYLYKIEDNSGM
                     VLQQIPAKFCMITMIENNVMRYAINIKKLTDKNIISFPEEIKNIYKKYKSNLLTREEL
                     IDNTYFQLSDKAVAFNYDLDSVKGVPFFCFIFDDLMELEDMKDLKSTNAVIESIKLIH
                     QKIPFGKNDEPLVDLNLIPIYHNSTKANLPKGTAITTNPLELETHTLSDGKSKINDYV
                     KEAKEFIFDNAGINTALLNSDKINNESILNGIIADSLIPMRIQQMIENWVNFELNKDK
                     KANLFNMKFIGTTHFNKMNLSKQYREDMGYGGSKSLFIASTGFTPLQAINTLQAEKLM
                     GFDEFLIPQQTSHTQSSGRPDKSDIGTDNGNSTQAKGNGEND"
     gene            complement(99708..101456)
                     /locus_tag="KRH82_000316"
     CDS             complement(99708..101456)
                     /locus_tag="KRH82_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653619.1"
                     /translation="MRTKYEKRELSSNDSSRNLLESIGEYWGAFYLANPHRFCMDYFG
                     FNLHLFQQILIYMMMKSDQFVFIASRGLGKSWLLGVFCCVIAVLKPGTCVLIAAKRKK
                     QAKLLITSKILGDLYLKSDTLKREIKSFQVNAQEVSIDFWNGSRIEAVVSNDDARGYR
                     ANVLIVDEYRMVDEGTVNDVLVPFLTNPRQPGYLQNPKYRYMQEENKEIYLSSGWYSQ
                     HWSYKKFMETVKGMLSGEDMFACSIPFTCSLEHGLLTKKRILKEMKKESMSDASFMME
                     YCGVFYNESDDAFFKSSWVNPCRVLESMFYPPSDIEYLENKKKRDKKYHLNKIKGEIR
                     IIGADIALARGVKNDNSIYTLMRMLPNEGTYKRCVVHIEAYNGMEAEKQAIRLKQLFS
                     DFQADYMILDTQGIGTTVWSYIQKANYDSDRDEWYDAYTCFNEDNTVDKSLAKKSLPV
                     VYSMKAYADENHKMAMSLRDVLTNRTLELPISDIEAKEMILEKEMIKADEIDKKAELE
                     AKYIAPYLQTTALVNELINLEYSADGGKIKIKEKSGARKDRYSSLAYTNFLADYLEEK
                     EKRKNRNNQKTVMIYW"
     gene            complement(101446..102345)
                     /locus_tag="KRH82_000317"
     CDS             complement(101446..102345)
                     /locus_tag="KRH82_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653620.1"
                     /translation="MAISKTKCLNCGEEKYTDRYFWKSHSEIFTLNKRLPVCKECFRA
                     RFLLLNGCYNGELVKALKHICFNFDVYFDEKLAKELADKKNKDELIDEYMKIINRNSK
                     YKGKTSLDNLLKEIYTGNNNDKNIVINDEIKLKWGRGFDDYEYKILERKYKEYEEYYE
                     PESLTERKLFEEICIIELEKDKSREKGDMKAFNDLSKLVSSKMQDAEIKPSQKKKAGD
                     SQDDTFGMKMMIYEKNQPVKDRLKEYEDVDGFEAYVNKHMKKPLAVALGLATGKYSIN
                     DGDKDIKFKDDVRDILEGNKNED"
     gene            complement(102476..103675)
                     /locus_tag="KRH82_000318"
     CDS             complement(102476..103675)
                     /locus_tag="KRH82_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653621.1"
                     /translation="MEDILKKKEDESLIDYRIRIRLAKVNKEIDLDWGEIVELLGLEC
                     SPDHCRKVSYGLKEAFDYLNSKVQDNSTQEEIDKINEKILELKKIKVQLSDERSLVNK
                     KIREYSRIDNIIDLFNNKIDDISLHKPFLSDSSYKCYESSNQEAIMLISDIHYGLETI
                     NAFNRYNSEIFKIRIQYLKDKIIEYSKLHKVKRLHVMLLGDLISGYIHNSIRLENREN
                     IVEQIIEVSEILSEFIYELSKEIDKIIVYSIGGNHDRVLPKKDENLDKDNFTLLIDEY
                     IKLRIKNINNVIFQKNIYDNDIIVAKICGNTCFGVHGDKDKMSTAIPKLTSLIKLIPD
                     YIFMAHLHNCKEDNYGESEICVNGSFSGTDSYAKNLRLSSHAMQKLMIFNESGRICTY
                     NINLSKL"
     gene            complement(104312..104929)
                     /locus_tag="KRH82_000319"
     CDS             complement(104312..104929)
                     /locus_tag="KRH82_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653622.1"
                     /translation="MVKYNVHKALAEKKLLEDKIDRCISNFKIVGTKKGSDKNVYETK
                     TSVEDFNVEVSSRYQQIEDLIYNYNALDKAINISNAITNVQIGNKNYTVLEAIKRKNS
                     IELDKSLLRQMVSNYDCMMSEVNRRNEEVQKNTDRMFEEKEKSKDGAELISFYKKQQE
                     WSLVDPLKVREKIEKLRDEIEEFEKEVDFALSTSNALTIIDVDLK"
     gene            complement(104985..105075)
                     /locus_tag="KRH82_000320"
     tRNA            complement(104985..105075)
                     /locus_tag="KRH82_000320"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(105040..105042),aa:Ser,seq:gct)
     gene            complement(105643..105921)
                     /locus_tag="KRH82_000321"
     CDS             complement(105643..105921)
                     /locus_tag="KRH82_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBG8653623.1"
                     /translation="MKKVDFLKEVAEELGVSQIRVREILDVIEKKRNEVLQDGEELTL
                     MGVKYLTKIQKGKEGEITLKDGTKKPWKTEEKRVPKLKIAKSLKDAII"
     gene            complement(106055..107497)
                     /locus_tag="KRH82_000322"
     CDS             complement(106055..107497)
                     /locus_tag="KRH82_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653624.1"
                     /translation="MIYNNNNFYEEIDGKSAQDYIKNLDYSIDNSKDRIKYIEERLGV
                     KHTWFEESNRNYIDTFYNTLTKRNENIITRVKYQEKKQFNDKFWENIFEQTSDSPLDK
                     DGVYYVTIDGEEVVMDYNRFITWCGYNQINPIEYINVKNPFSNSNGTWEYTHHNTSKI
                     KLILNKDDSIYSTSNIAKTLEIMGSYILSVDDKPKETKIRIYNSKELFDRACQEEALL
                     NKIAPANGGNINSNTSNKDGFLEDNSFAFFQLPKNYKKIKDIKVKPKDIKKYPIIKTY
                     SDTYEWYKAKYKELGHKQLSKEELKLKRMVRKNLNALKNDMTDVKNSIERPIIWKAPL
                     ADAGSPEWDYLDMFDKSHVKELLKIQKGNDLQDDLTCIVMDLNNIISKIEFTTVQKDI
                     LNLYRKDKSLEFISNLMNITPQAINNQINKIVNKIIDAYEKNYEENYYYISVCKGKYK
                     KCSRCGKIKLLSRFDKNGKKGYRSNCKNCN"
     gene            complement(107500..107748)
                     /locus_tag="KRH82_000323"
     CDS             complement(107500..107748)
                     /locus_tag="KRH82_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653625.1"
                     /translation="MKEKKIELIYLEDLDESEKTGVHKNRYQILNEEYEQMIDTYTEM
                     SKRSSYDIVNERHKEDFKDELWDYDDTDYDDGLQGKEV"
     gene            complement(107926..108789)
                     /locus_tag="KRH82_000324"
     CDS             complement(107926..108789)
                     /locus_tag="KRH82_000324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653626.1"
                     /translation="MKRGEVLEIGKRKKSFSPEQRAIINNKKELPYHNFKLGGFVFCT
                     YVKNELLFNEVNISKANISRLIYLATYLNYNTGEENLLVRYSQFKEMIPIDRKNMREI
                     LNLKDRAFRNFLADVKKCELLYESNNKFYINPKYFTKGIPNFENKEYTRIYINTSRFL
                     FEHCTPRQHKQLSYIYQLIPYIHFESNILCLNPHETDISKIKKISLYKICQLLNISTI
                     KQDMNKFKKELLRFYIKVEDDKYYFFKYVIVEGNNKNTDYFIINPCVIWKGNNLNLAK
                     KTIDLCFFNCI"
     gene            complement(109061..109333)
                     /locus_tag="KRH82_000325"
     CDS             complement(109061..109333)
                     /locus_tag="KRH82_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653627.1"
                     /translation="MKKSSSFYLEEDIFGEIEKYQNDKNISSRNTALERIILEWKNLQ
                     EENKLLKQCLGNGVYRTNKKTNVTEEKKDIKRENPIIKNIFNNMPD"
     gene            complement(109346..110260)
                     /locus_tag="KRH82_000326"
     CDS             complement(109346..110260)
                     /locus_tag="KRH82_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBG8653628.1"
                     /translation="MEENYQVIGLDIGRGYVKGYSKYNGMVKECLFKSVFGDGRNIDF
                     EKYENPIYIDFESVSYFVGSLAEKESITPIRNSDDSKVSFTMRILVAAALNEIAVADE
                     VKLMMGVPYKSFRKTTLKEVVDTYKGKTFKVKDKIKGGHKEIKISDISIFREGDAALF
                     HTLEGKVNEDKAVGMVSIGFRSTEMSFFEKGFVFNDKLSDTLEAGNQDALTMVQKQLK
                     DRGIIRELNEIDSSNDYDELKKVAYIMASESTAQRISSKWKNIDEMDVYVSGGTALHM
                     TFDNRFKVSKDAQMATAKGLFEVGMEQF"
     gene            complement(110682..110870)
                     /locus_tag="KRH82_000327"
     CDS             complement(110682..110870)
                     /locus_tag="KRH82_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653629.1"
                     /translation="MESGLFVSRILCVVLSFPHFKKIADGFTDEIALYFPHKTNIYLK
                     IFLRFLLLNYILNKENIK"
     gene            111366..111524
                     /locus_tag="KRH82_000328"
     CDS             111366..111524
                     /locus_tag="KRH82_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653630.1"
                     /translation="MRITKGKIKELIELCHQLEKLFVQVFKSLEHILISLCSCIGWLL
                     ILIYIIKH"
     gene            111777..111968
                     /locus_tag="KRH82_000329"
     CDS             111777..111968
                     /locus_tag="KRH82_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653631.1"
                     /translation="MKLEKLIDIRKEKKYSQEDIARMLDISLRNYHRKEKGENQFTVS
                     ELEKICSYLDIESKELLDI"
     gene            complement(112182..112493)
                     /locus_tag="KRH82_000330"
     CDS             complement(112182..112493)
                     /locus_tag="KRH82_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653632.1"
                     /translation="MNRLRELRKEKGYSTQQVGELLGVHYVTIQNYETNRRKIDNETL
                     IKLSNIYNVSIDYILCLTDNRENIQLEEEEKQLLNNYRELDTKSKTIVQEQVNTLKKL
                     L"
     gene            113225..113548
                     /locus_tag="KRH82_000331"
     CDS             113225..113548
                     /locus_tag="KRH82_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653633.1"
                     /translation="MDEKILELLQKMDTSINDIQGEIKWINTRLDSMDGRFDGIENQL
                     SDLKEGQEEIKKKLDLTYNQVARNMEGITEVGEKIDTLKNDMNFVEMATSKNWNEIAK
                     LKSIK"
     gene            113560..113793
                     /locus_tag="KRH82_000332"
     CDS             113560..113793
                     /locus_tag="KRH82_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653634.1"
                     /translation="MDEKTLELLREIQESIKILNDKLDEFDYTQDKIKSNVEGLLECF
                     SRIDFRIEDLENGQTSLYTKLDIVQNETAKSIK"
     gene            113888..114076
                     /locus_tag="KRH82_000333"
     CDS             113888..114076
                     /locus_tag="KRH82_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653635.1"
                     /translation="MYEQRKAKVIFNKGAGNSRGESYTNRVTIPTTWIKHMDITKLDR
                     EVLLTFDGNKIVIEKIDE"
     gene            114306..114500
                     /locus_tag="KRH82_000334"
     CDS             114306..114500
                     /locus_tag="KRH82_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653636.1"
                     /translation="MNLERLKELRLERGYSQQQFATYIGLSTSTYTDKEAGKTKFKVE
                     ELEKILKFLNLDPLELLDLD"
     gene            114652..115365
                     /locus_tag="KRH82_000335"
     CDS             114652..115365
                     /locus_tag="KRH82_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8653637.1"
                     /translation="MLNIYITNLGKYNEGELIGEWAELPVNEEELQEILDRIGINEEY
                     EEYFITDFETDIEGLEISEHSNIEQLNELAMKLERLEEYEIEELKALLERGYIDFYDM
                     LEGDICRLSGNYTFIQLDDRSPLDDENLGRSYIEEICCGDLSCIENIAYYFDIEAFSR
                     DLRFDRDMIIENLYEEDIEYYENMTDIEFAENYIERLGDIEELGQETLERYFNYELYG
                     TDLRYENICIASNYLAIVS"
     gene            115433..115573
                     /locus_tag="KRH82_000336"
     CDS             115433..115573
                     /locus_tag="KRH82_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653638.1"
                     /translation="MKKLIIKIKSLFKKDLDSSYWSTTESIILKCGNSNQLKLLKQSN
                     KL"
     gene            115590..115811
                     /locus_tag="KRH82_000337"
     CDS             115590..115811
                     /locus_tag="KRH82_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653639.1"
                     /translation="MKINSKISNVVWDIKTKELNKQDILFIENFNPTIYHNDVDCYLW
                     SLDEKLPSGVWLENIKFNNEITEAKAIVL"
     gene            115856..116092
                     /locus_tag="KRH82_000338"
     CDS             115856..116092
                     /locus_tag="KRH82_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653640.1"
                     /translation="MINYSKYMTATDLINICDILEGETIGEAGTYNSLSTRLGNLIGL
                     DWALKGEELRQQLIQNINNMMYLDNENKIQYKEF"
     gene            116127..116630
                     /locus_tag="KRH82_000339"
     CDS             116127..116630
                     /locus_tag="KRH82_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653641.1"
                     /translation="MNKIIVFYDIEGYPVFQILVRNVKKYTRQNRIFKLVDSFIKKNI
                     NNINLNDGKIYDSSSWIIFTISKTGHYKLKLNLDIDYDILIKKLDIKKSKRESNSKTE
                     RELFYIGTGWCKRKEIYNLLTRQNQIGYEDYDTLTIDGDVYIRTYNEKCRTILLHSNY
                     QKILKEI"
     gene            116668..117030
                     /locus_tag="KRH82_000340"
     CDS             116668..117030
                     /locus_tag="KRH82_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653642.1"
                     /translation="MNKYLIGCIGNCLRSMKAIKTRFFLIDNNNIEDVTLKLCKGVEH
                     IAPFRYKYGLANYSFGCGLSHYLDTYNLNTVNGLDLNNTHLIMLTLNDLKNIVGCKTV
                     FDIDVEEKLLNYIKSYYR"
     gene            117081..117344
                     /locus_tag="KRH82_000341"
     CDS             117081..117344
                     /locus_tag="KRH82_000341"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653643.1"
                     /translation="MLINKAKGIKTSLETSSLRELKGYIKDLRKALSGYKYKNKIDEI
                     TEYQIDKLCYKIDNTDIFDLKYKEIEKYIDNLILIINFIFMEM"
     gene            117382..117966
                     /locus_tag="KRH82_000342"
     CDS             117382..117966
                     /locus_tag="KRH82_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653644.1"
                     /translation="MNEYILINYTKGKGACDHCGRTIKNIATIKNNVTGEVFHVGLTC
                     VEKIMKLNVTFYKALSREIKKHYKCMEYYSKGLDIETNLNKIVKNNTKYKEGSYAYKS
                     NEQMLEDAIAEVAWSLARMIDSCMRMNKLSKSGLIDIDILNSLFIKYKEYMSKFDENY
                     NKNKYKYKSCYTMKPLKVILDENEDLKELYKSMQ"
     gene            118284..118781
                     /locus_tag="KRH82_000343"
     CDS             118284..118781
                     /locus_tag="KRH82_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653645.1"
                     /translation="MKFKNIAMGMLLGLIIVGVAGATKVKAAELDNFYVETTDRVVEI
                     LEDESVVLYDTKEQVYNFYPVCLGDWNYSFKNKKDLDRAVATYKELSNNISHSKDVYV
                     INKLNNNGNIKVFLSDGSSIVYIKNDNKYYFYPSCMGDWYLTLDSKIDLSNCVGTYFD
                     VEVAI"
     gene            118778..118936
                     /locus_tag="KRH82_000344"
     CDS             118778..118936
                     /locus_tag="KRH82_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653646.1"
                     /translation="MIRYMKDINNISLEDADMLAKEGFCFIIKDGKLRGFKIEKIKIG
                     GYENEKNN"
     gene            119190..119525
                     /locus_tag="KRH82_000345"
     CDS             119190..119525
                     /locus_tag="KRH82_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653647.1"
                     /translation="MIIDYNEEIEENERCIRSFIKELKSSVGEEFTVLEYDNFVQEKY
                     NYLVNKTDSWDFFMEGEVYNYLDCGSYTYSGLGKDYDVDINIVFDVIKINSEEDYKSI
                     IKIKDIELL"
     gene            119632..121077
                     /locus_tag="KRH82_000346"
     CDS             119632..121077
                     /locus_tag="KRH82_000346"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653648.1"
                     /translation="MKEELNIVPFLAESLSINKKCYKLIDKYYNENKLKYSSLAKDNI
                     FYNSRIASEGSIIQEYYFKKSLGILLERDEKKITKIFKVGYTIAYNYIISIQTFKAST
                     FLRKLMLKNKIESFSEDELNGNMLVAISLCGALGKEVDESDEIYIKVIRNLILRNENY
                     KHEKVLSIDRLSKDEQKLISKIELRLKSTYLKEYIPSSYTIGIDGSIGTFNLDALTDL
                     DRNLLGFDYIYDLEELSLISIVGRDILKSKQIQELILCYCNLQKNIEDENSINYEDLF
                     KFIIPAIDIRYLAREYKKAKQFFFNNFDEELKESIEEKDLKLDSIKKENSLLEAENEK
                     LKSELELLQKDKLRLENEIKAQLTSKEELVQLRNFMFNQQQEQEEKVLIDESINLKNI
                     KAIIFGGHPNWILKMKEKLTNFEFISADTINFNVNILNSYEYVFINTNFIGHAMYYKI
                     IENLNEDNKLRYINNINVDRAIEAIKNAIKI"
     gene            121088..121456
                     /locus_tag="KRH82_000347"
     CDS             121088..121456
                     /locus_tag="KRH82_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653649.1"
                     /translation="MIDIDINKRIKEIREDINLSQQKFGEKLGVSRDVISNIENNRVE
                     VKTVFITHMCEVFSVNQVWLETGEGRKFIEQECDIVLGEVFANITVSKNENLNELIIN
                     ISKLNDTYINNLNEIVKGLI"
     gene            121476..121856
                     /locus_tag="KRH82_000348"
     CDS             121476..121856
                     /locus_tag="KRH82_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653650.1"
                     /translation="MSDETISKRIRKIRKNANLSQPDFGGKLGVSKDVISNIEYDRVE
                     PKPLLINHLCSVFNVNKEWLINGTGDMYVSVKEDISSILGEVFYKIASSKDENLKELI
                     INISKLDATYIASLNEIVKRSIQR"
     gene            121862..122209
                     /locus_tag="KRH82_000349"
     CDS             121862..122209
                     /locus_tag="KRH82_000349"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653651.1"
                     /translation="MCDIGKRIKILIENEKIKQVEFANKIKVDPSYISKFLSDKSKVI
                     PSDRLIDDICSTFNVNKEWLKNGDGEMYIENKCNRNISEATDLLMELSIEFQECAINQ
                     IKDLIKLQHSLKK"
     gene            122296..122628
                     /locus_tag="KRH82_000350"
     CDS             122296..122628
                     /locus_tag="KRH82_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653652.1"
                     /translation="MKKYFKEEWNYIADAGYEIDNIESTKIMVNNFEVSIKMSEDFKH
                     KGDIEYTFNIPYDHEIFTKEYNEVLNLEQPCDCDQFCDELSDLRARIEEGIEKYLKDN
                     DKLKEIEY"
     gene            122773..123249
                     /locus_tag="KRH82_000351"
     CDS             122773..123249
                     /locus_tag="KRH82_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653653.1"
                     /translation="MDKKEAKKFLKVVDMNIDKIKEEATKIYKECYLIETTDTIRISI
                     NLKGVVKSTISSWQGYSDDIFNMREIIVYEFSQGEVQIEDLLGELCFLNDYEEFATWC
                     DTESETLNWNSYEKFNKENFDELVERNIEDSLPDFLEELSESIENCKQELKSMIEI"
     gene            complement(123555..123854)
                     /locus_tag="KRH82_000352"
     CDS             complement(123555..123854)
                     /locus_tag="KRH82_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653654.1"
                     /translation="MDVEQSKKVYLSIGKELSKKMTKSELTKFSQEVANYLQYAGLDK
                     NMKIKLFQTILEMVARKKITLSSDSEFTEGILQSDEAEMTTNIGFIIEGLSYHND"
     gene            124240..124641
                     /gene="tnpA"
                     /locus_tag="KRH82_000353"
     CDS             124240..124641
                     /gene="tnpA"
                     /locus_tag="KRH82_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBG8653655.1"
                     /translation="MYKSNENIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIDNQPIRSKKK"
     gene            124638..125801
                     /locus_tag="KRH82_000354"
     CDS             124638..125801
                     /locus_tag="KRH82_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBG8653656.1"
                     /translation="MIKTHRVKLNLTRTQFELIREKQMESANCWNHIVNLSKEYYFEH
                     KQWIKKNDIQKSIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYKTHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            126088..126660
                     /locus_tag="KRH82_000355"
     CDS             126088..126660
                     /locus_tag="KRH82_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBG8653657.1"
                     /translation="MTWNDLKNNDITYIVEYINSKLNDSKSLTKVAIELGVSESSIRK
                     YLTKRGYKRINDEYVFIGDNSMTKVVNNRQQSNNDNRFNMTIEDDNNHNIVIDNQFKN
                     NIISLAKDYDKIQDVLNWFENKEDTNVIEVVQDGIKIDLPSKDAIRTTVRLNKDAWNL
                     FDEFCEKFREFNKSDLMSMALLEYIKKYDK"
     gene            126737..126910
                     /locus_tag="KRH82_000356"
     CDS             126737..126910
                     /locus_tag="KRH82_000356"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653658.1"
                     /translation="MVDKITIDEVLEFIKSKGYIYSQEIRKELDNLCPVSDNEIDKCI
                     EENDDVFRRLASK"
     gene            126907..127275
                     /locus_tag="KRH82_000357"
     CDS             126907..127275
                     /locus_tag="KRH82_000357"
                     /inference="COORDINATES: protein motif:HMM:TIGR01550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBG8653659.1"
                     /translation="MITLEYICKINKKMIERYGGAGIGIRNKNLAISIIDGINQEVFG
                     RVMYPTVEEKISHIVVGIIQGHIFIDANKRTGLATLLILCDKYNIDVNYDKENLAIEI
                     ALNKINESDLSNMLKKWNKK"
     gene            127472..128398
                     /locus_tag="KRH82_000358"
     CDS             127472..128398
                     /locus_tag="KRH82_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653660.1"
                     /translation="MNYNLKNENVLSELLQNEDEKTRIGILKVYKVLIFWFAKEGKLV
                     EEGNDYIVEIVGNDKEKIVKDMNQNKTYNAIMAIIFKINKIFKTLNYDIHFSKPKNLV
                     AEFDLSKYLTQDEVLQVCSKLTNAQDKFIIYAAFCGLIGKDAEDLRSIKIKDIDLEKR
                     LIKLKDTEFKLDKFLFDFTKDTLEQKEYKQYLEQGSNAAEFYLFNSNSEYLIKTKPDA
                     RYGNGLKEMGYSTIRKRLLIINDYLDNKVQLNFTNLKISGIMHQMQLNEKKYTQSGYW
                     TNKSLKEFKEDNNLNFKIQEVLSIYKQKYIKE"
     gene            128403..129971
                     /locus_tag="KRH82_000359"
     CDS             128403..129971
                     /locus_tag="KRH82_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653661.1"
                     /translation="MSKDVKENISNEQKDLNKINLIYHIIYDNDRFKMITRKYFEIFR
                     LKGMSAEEISLKFEEFLYSLISDKFKKINTVNDVKKLRNQENSSSLKLKKRWSDMTLD
                     SLSEDTKSSRKKSSKYLKKELEIVESEYLKNGRIISAGVKNPKELKEQRKDFLDEWKS
                     SSNYNICDYPYLQELSTSKINSAFIHDILMCITEVLKDDYDFDINKIAIKTPPHISPG
                     IFLPFTKGKRYSHLNVKKNENEYMSDDYSAKNLSGKQMNFFYKFSIGQDENIENLKLE
                     LINPDTEKRALPKIYLDKQDLEIIRFVYTYSHMNSFSFYLGDLVKYLGLSDGKKNYIN
                     IKNRLLKLPYYTFYSNQTNDKGELKYEISFNLFSSTTIVNDENNNNRELVKITKSFIE
                     EVERVNTDIMYRNELEKLQLTQSINLAYFLEGRRSFLISCGEDIKNKSFRYDIEDLKF
                     DVHLNKSKTVKQNMEYLELGFNEIKENQFIIKDYKRGNSYFDVYFYEDFEKRKRLINN
                     TILSLPDYMIENKS"
     gene            130445..130711
                     /locus_tag="KRH82_000360"
     CDS             130445..130711
                     /locus_tag="KRH82_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HBG8653662.1"
                     /translation="MSLKYKDKEFVLVEKKNINELDNSNINYIDLKDKQYYVVTQGRR
                     SKRFNNEDVSEIKKDLDNGMSLRKCAEKWNCSTRTIQDIKQNKY"
     gene            130780..131025
                     /locus_tag="KRH82_000361"
     CDS             130780..131025
                     /locus_tag="KRH82_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653663.1"
                     /translation="MKWSEVRNLYPNSFVKLEILESHIQNEKEYIDEVALIKVIPNNK
                     EALKEFNRCKDKEIVYNTKNKEFVIDIIKHIGIRRGL"
     gene            131027..131413
                     /locus_tag="KRH82_000362"
     CDS             131027..131413
                     /locus_tag="KRH82_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012058279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retropepsin-like domain-containing protein"
                     /protein_id="HBG8653664.1"
                     /translation="MKNFKYKNGLLYTDIEILIENKNILVKDTIIDTGASHTIISSSY
                     LEESDIGFNDDDTIVKASGYGGTVQYSVRKLVNKVACGDITLENIKLDFGEIDPEEKV
                     NGLLGLDFLRNANLIIDLVDNLLIKK"
     gene            131443..131706
                     /locus_tag="KRH82_000363"
     CDS             131443..131706
                     /locus_tag="KRH82_000363"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain containing protein"
                     /protein_id="HBG8653665.1"
                     /translation="MSIKYKDKVVFIVDSSEKEKLDKSGIAYETLENENYYVVQQGRR
                     SKRFNDEMQNQIRKELENSTIRAIAKKYKTSTGIIQSIKDFKY"
     gene            131793..132056
                     /locus_tag="KRH82_000364"
     CDS             131793..132056
                     /locus_tag="KRH82_000364"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653666.1"
                     /translation="MSIKYNNEKVFLVSENDKEKLEKAGINFVSLDGNYYVVSQGKKP
                     KKFTDNEIREIKNDLDNGLSIRKCAERWDCSTNVIMKIKQNTY"
     gene            132130..132306
                     /locus_tag="KRH82_000365"
     CDS             132130..132306
                     /locus_tag="KRH82_000365"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653667.1"
                     /translation="MLENLIKEYFLDSFCIENINTDMKNLEIKIDNIYNCLNNTLNEN
                     QRKLLSQFDELLKI"
     gene            132323..133501
                     /locus_tag="KRH82_000366"
     CDS             132323..133501
                     /locus_tag="KRH82_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653668.1"
                     /translation="MQELKPVARISKSKLKDILDIFKTSIRKVEKIDYSACNSCAIKN
                     NPSFDSNKLNEFCSNCPKLKTISEFSYVAEKETELGMIEIVTNESKCMALSKSAIKQY
                     LAYHFIVSNKNYVRKAVSFQNIADICNVSVVTARHNHNVLLQVGLVYSTEIKRGKFDI
                     VIDEEYKNHLKKEDGGKGYLTMSLDTLNHLLSFENVNELKLEIKKLIWADAKGSKLGK
                     RIRFKKDNLISILPEYIKKSNKRIEAFLRSSKTLFDVSNDTIDTKRYETKETISEKYT
                     EPIRIQISKFFDNTGCSLSSNYSKVLSQINLDRYNLFEEDLRSKLDMEKDIIINDLVG
                     LSVQYGVTRVLAALDYMFNKYTFDEEDINYNEIRNPGAFIRTLIVQSINKNGSLAIAI
                     "
BASE COUNT        49331 a        17286 c        18076 g        49036 t
ORIGIN      
        1 aaaaaaaaat actaatgcat caacaagatg ttaatattga aatttatatt ttattttatt
       61 ccttacaatc acttcgattt atagtttttt ctgactttct aattattggt tttaattatt
      121 acttttaatt tttgttttaa attctgaaaa acatttatta tttatacttt aataaattaa
      181 aagataaata atatcgaata tatgttcttg aaatatcgaa caaaaagagt tataataata
      241 atgtgctaaa aataattggt atatatcttg tacacataac aagaacatat gtttgcaaaa
      301 cggttaattg tttatatttc tatctatttt ttatgtctta tattataaag ttaaatataa
      361 aattaagata aatattatta ataataaata gtttgaaaat tgcaaaatat gtcgatggct
      421 ggtaaaaaat ggaagaacta cttggataga atgtatgtta caatgtaatt aattaagtgc
      481 aaaggggaag catttataat aggtatactt tattttttct aagggggaaa atttatgtca
      541 gaaggaaaaa ttaacaaaga aaaattaatg aagctaggta atatgctgtc agaattaaaa
      601 aggaataata aagataaatt tacaaattat aaatctgaag ttgagaaata tgaaaataaa
      661 aaaagaggag cataacatcc tctttttact tcttattttc ttcctctaaa aaaacctcag
      721 ctacattgta taatcttttt tgtgcttctg gacttaattt acttatcatt cttaacattt
      781 ctttaatatc atcatcaaaa tccatatcta aagttgggtc ttgaaatata tccccttctc
      841 ctgttcttaa ccaattttcg tttacattaa attctttgca tatatcattg attattctat
      901 ctgttaaatc tctcctacct gtttctagag aggaaatgtg gtcttgagat agaaataatt
      961 tatttcccat ctgtgtttga ttcagcccta attcttttct taaagttttc aatcttttat
     1021 tcaatattat cacctccctc tttaaaatat attatcatat aaaatatgtc tttgcaataa
     1081 aattgatata aaatatgtca aaaacatatt acctgttgac aatatgctaa tgacataata
     1141 taatttaaat atgaaatgtc aaagacataa aaaggagtga taatatttgc ataaaaaaaa
     1201 gatgaatcaa aaagagcttg agttattagg gaaaatgttt ttaaaaatta aaaaaataga
     1261 taaacagaaa tttggagagt taaaaggttc tgttaaaaca tcacttgaat atgaatatat
     1321 tttagttaat aaaattagat aagtatacat atgtacattg aaaactgaat attcacacaa
     1381 ataaaaagtg caactataaa ttaaaaaatc tataattgca catattattt ttagaggata
     1441 tgatttaatt ttggttaaat aaagtccatt ttataggact ttatttttta aattcactat
     1501 tagtatcatt ttgaattttt aataatccat ctatctggct taatacaaat tctttgtatt
     1561 catatttcaa taatttgtat ttttcaatta attgtttatt tagataatct gatttgttta
     1621 tatctttttc atcaacttca tcatccaata agtaatctaa tgaacaatta aatacatcac
     1681 atataagttt tgctttttga atagaaaggt ttttcgtctt tccatttatt atatcagata
     1741 gtgtagaagt tggaatttta gttttagcag aaatatctgt taatgttaac ccactattat
     1801 ttattaaaaa ttttatcttt tttcctatgt tcatatcaac atcctcctct ataaatttat
     1861 gataacataa tttcgataat ccgtaaagaa atttattaaa aatttaaaaa acatgataaa
     1921 tggattgact tattcggaaa aacggaatat aatataaata tatccgaaaa aacgaataaa
     1981 gaaggtggag atttatgttc gtgaactgga aaatcgaaat gattaaaaat aacataacag
     2041 ttaaagaaat agcaaatatt cttaataaag atgaagaatt ggtgaaaagc attatagacg
     2101 gccaacagga attgtcaata attgatggtg tgaagataag ggaaatattt tttccaaaat
     2161 tatctttaga ttatttatat ttagaataag tagacaataa ttaaaaaaat aaatatgaaa
     2221 ggagatgact agaatgaata atttaaacat caaaggaaga caaaaattta tggatttaga
     2281 aataccagtt atagaaggtg gttttggtga agataaaaaa tgtatgacgg ataagactat
     2341 agccgagatg cataatatgg aaaccaagaa tgtaagagcc agaataaata gtaatatagc
     2401 tagatttaaa aaagaagttg attatattga tttaaaagtt gcttatgaga taagcgacaa
     2461 tttacaaatc ttgaaagcac ttggttatag taatatgcaa atatcaaaag ccgataatat
     2521 ttatctttta tctgaaagag gatattcaaa attaattaaa ataatggata ctgatttagc
     2581 ctgggaaata cacgataaaa taatggatga atacttcaat atgagagaac atcttataga
     2641 tagttatatg attcaagatt ctattgaaag agctaaaaga tggatagaag aagaaaaaga
     2701 aagattatta cttaaagaaa caattcaagt tcaacaacct aaagtagaat atcatgacaa
     2761 agtattaaat cctgacaaat tagttacgac aacagatatt gctaaagatt taggaatgac
     2821 agcacaagca ttaaataaat tactacattt aaacagaatt atatatccgg aaagaataaa
     2881 tggtcgaata aaatgttgga aaccatataa aaattattta tggttgatac ctgaatatgc
     2941 agattttaaa ataacagaac atgatacgca gcttaaatgg actgagatag gtagaaaatg
     3001 gttaatagaa tttgtagaga acattaaaaa aataagttaa atcaagaagt taaaatgtac
     3061 cttgaaaagt agatatttaa aaatataaaa gataggtgat taaatgataa aacaaatact
     3121 aaataaaaga ggtagtctat taaatctagc aagtgagtat ttgacagaac aagactacct
     3181 caagtttcaa ggatggtata cacatagata tagtaaactg gatgcttatg atgcttctat
     3241 aaatgaatat ttaaattata aaaacgacaa aaaattaata acttatgtat ttaatttaaa
     3301 atttcaagaa gctctcatag aaatataata ttactaaaaa tggtgattga aatgaattat
     3361 aattatgtaa ctaaaattga cttgaaatat ggaaatacac aatttggatt tgagaaatat
     3421 agcgatgctt tagataagta cagagaactt aaagaagaat ttaagtatgt tccatgtatt
     3481 ataaaacttc attcatatgt agcacaccaa gatttatatg tgaaagaaat taaagctgat
     3541 ggttttgaaa agaaatattt agatattaaa aatttaataa aattgtttaa agaacataaa
     3601 caaaatatat cagatgaact aagtctttgt gataagaaaa aggaagaagt attacatgta
     3661 atagaagaaa tgaatttaga cacagcttct ttaagtgata agattgatac cattaaagaa
     3721 ttaaaaaaca ctttagctaa gagaaggttg gttaaatatg aactaaataa atactttgcc
     3781 ttttgtaata cattatatga aattgaagaa gagttaaaaa aatatgaatc taaatataaa
     3841 caaaaagaaa atcaaggaaa aagcagattc aaaaaaaata aaaaataggt gattagatgg
     3901 aagaatatca atttaactta ataaaaaagc tttgtgctga aaggaaaata cacaaagctt
     3961 ggtttaggaa tattgaaaaa tgtggttgtg gaggtaaatg taataagaaa aattgtaaga
     4021 tgttagaaaa attataggga ggtacatatg gaaaatcaaa ctgaattaac agaaaaagat
     4081 atagagaaca ctttaagtgc tttaaatatt attaaatata tttgtataaa atctaaacat
     4141 tgcaaaaatt gtcctcttgg atatatgaaa aatcttgatg aacataattg tatgctatat
     4201 gcattaatag acagagggtt gctaccatgt gattggaatg caaagaaagt tacaagattg
     4261 ttagatgcaa tagttgaata aaattaacaa agaggagaag atatatgata catgaactta
     4321 agatattacc taaatattat gaagctgttt caaatggttc taaatcattt gaaataagat
     4381 ttaatgatag agattttaaa ataggagaca ctttaaaatt acaggaatat atagatggtg
     4441 tttatacagg aaggagttta caaagagaag tatcttatat acttaatgat tcaaattata
     4501 ttaaaaatgg gtacataatt ttagggttaa taaataacac aaatcattat atgtttaaag
     4561 ttgtaagaga ttataaaaaa gaaaattatt taatatgtag acaagggaaa gtgttcatag
     4621 ggtatattct tgggaacttt gcttgttgca aggagtcttt agaacaattt actataccat
     4681 tagaatatat agagaaaata agtagagtag aatttaaacc attgtaatta aaatcaagat
     4741 tttaatagaa aaggagtgat taaaaatgaa gaaaaatcca ataagaatta aaaaatgtga
     4801 ctgtggtgga gatatatatg aacttaatac acaattaggt actatgtatc aatgtaaaag
     4861 ctgcggggag atgtatagat agtgctgaaa tattagctaa agaagatgag gtgaagtcaa
     4921 tgagtaaaaa agataagtta tctattttta taagtttaat attaagacat aaaccagaaa
     4981 ctattggaat taaattagat gactatggat atgcagatgt taatgaattg attgaaaaaa
     5041 taaataatac tggtagaaat attaatatag aaatccttga gcaaatagtt aaagaagata
     5101 ataagcaaag gtacagtttt aatgatgata gaagcaagat tagagcaaat caaggacatt
     5161 caattaatgt taatgtggaa ttgagggaat tagaaccacc aaaatatctt tatcatggaa
     5221 cagctactag atttttagac aatattaaaa atgaaggtat tattaaacaa agtagactgt
     5281 atgtacattt atcaagggat atagatattg ctgttaaagt tggtaaaaga catggtacgc
     5341 ctgtaatttt aaaaattaat acaggcaaaa tgtatgaaaa tggttataag ttttacttat
     5401 ctgaaaacaa tgtttggtta tgtgagtata taccatttaa atatgtagag atttttgagt
     5461 agttaaataa aattattcag tgaaataaaa aatgaatgaa ggtgtaatga aatgagcagg
     5521 tgtaaagatt gtttttactt tgaaaaaaac aagatagaag agagtggtat atgcaataag
     5581 aaagaaaaag aagtgtataa agagaataga aaatgtgaat tttatgaaag taaaaaatgg
     5641 aaatcaatga atatagatga attttggatt gaaatggaaa gatggacaaa tgaaaaagta
     5701 aataggtata taatatattt ttctgaacat gacagtattc agattgatat tgtccaagat
     5761 attaatagac ctaataatcc tactgatgat gaagttatag aagaatatgt tgaaaataac
     5821 tacggttatg taaaatatga agttattgat ttaggtactg tagagaacgt taagttgtaa
     5881 aattaggagg gaattaaata tggagaatat agaattaaca cctagagatt attttgaaga
     5941 tattaaaaat agaaagcaaa aaaatacaaa tgaaaagctt gatataatat atgaaaactc
     6001 tttgattctt ttaaacaaat atattgtaac tggtcaaaaa aagggtgcta agaaattaat
     6061 gtttttactt gaatgtattg aaaaagaaag aaatgtaata gagctgggaa tagatacatt
     6121 tgtgtataaa gaagatatag aaaaatatat tgatgatata tctaaaaata cagtaaaaat
     6181 aatagaactt gaaaattatg aaagagaaat accagatgaa atagtagaaa taatagagaa
     6241 aacaaaagat atatttgata aaatgtatgt tttgtttact gattatacag gtaaaattac
     6301 aaaggaaata agcaaagaga gaagagataa agacccaata ctatttggtg ttttttcaga
     6361 tgagaaaagc agagctattg tagatagatt ctattatctt ggagattggg aagatgagta
     6421 ttgtgattta acattagaga aaatgataaa tgattataag aaaaaaggaa gacaagacat
     6481 attaaaacat ataattacac ctaaatcatt agatgagtta aaaaaagaat tagattcttt
     6541 agaaaaaaat aatgatacat ataagcaact tgccaatata aagccattac ctactacaaa
     6601 aaactctagt gtagaaccac ctaaattaaa tatatttaaa aaaataaaaa atagagtatt
     6661 taaaaatgaa aagtaatgtt gatttaacag agaataggga ttttagagct gtaagaggaa
     6721 gaggcatcaa tattttaggt atcgaagatg caccaaatag aatgttgaat ggttttagtg
     6781 attttggaat tggacgtctt tatggtaaaa atttagaatt tgaatttaat aaaaatgaag
     6841 tatttttaac tggaaatgcg aatgatagag aggaaaaaaa gtttcttata ctttgtgaag
     6901 aaaataaggt gtgtgtcaga tgtggagatg aattaaaaga gagatgggat aaagtaagca
     6961 tagaactatg taataaatgt tatgaaatgt tagatgttga gtataaaaat aaaaagataa
     7021 ttagagaatt attttttaga gatagagatg taaatataga gttactttaa gaggtatata
     7081 agaaaaataa gtagaggagg aatttatatg aaagatgttt ggttatatag ttgggatgat
     7141 gaatgtttta gaagtgatga atacgaaagt aaagaagaag ctgtcgaggc agctaaggaa
     7201 gaacttaaga ggctcggaga aattaaacga tgggtttata ttggaaaaaa agaagaagct
     7261 gatattcccg acatagatgc aaaagatgct ttagaatgta ttcaaaatag aattgatgac
     7321 gaatacggag aatatggaga agattggttt gaaaatatac gtgctgaaga catattgata
     7381 ctagagagta gaataagcga agtatttaaa aaatggatag atgactttaa atataaacca
     7441 tattggtttg ctgttagaga tatagaagaa atagaactaa aaaatgttgt taattaaaac
     7501 tagtattttc aatgatgaca acagtatgac aagaataatg agtatataaa ggagtgatgt
     7561 ttattaaagg ttttagatgt atatgcagac ataagttttc aaggataaaa gattgttatt
     7621 tgattacaac aaaaagtcag cagcatactt gtaagatttg ggtgtgtaaa tattgtggac
     7681 aaattgtagc tggttcaact cctgtttatc atcctaatat gaaagtcaat gagtattgtg
     7741 taaagtgtga gcttttagca tgttcaaata attatgaagg atattgtaac tctaaagata
     7801 aagaaattga atttaagtct atttgcttag aaggtaataa agagattttg cagtgtaaaa
     7861 attttgattt ggaataaaat ttagcttaag taggagaatt ttagaatatg aaaataaatg
     7921 tacatgttaa aactaataaa attggttcag actgtaagct ggagtttgaa atagatgatg
     7981 atgatttaaa agatatgtct gatgaagaga gagagggtta tatagataaa attgcatggg
     8041 attatgtttt tgaaaatttt atagattgga attggtatga ggttgaagat taagttaaaa
     8101 catttgtttt aatgtgattt tacctagtag atacaaggag gtttttaatg aaagagcttt
     8161 tagaagtaaa aaaaatattt gatagtttag catctacatc tagtagaaaa gaaaaagaga
     8221 gaatattaga aaaatataaa aataatagaa tgtttgttga atgtttacaa tttctactag
     8281 attcaaatat tctcactgga atatctaaga ataaaatatg taagaattta aataatactg
     8341 gtcataatga attagagaac atatatgata tgcttgacta tttaattaag aataatactg
     8401 gcagaaatat agatgtaaaa acaatacaag tatttgccag taaagatgaa aaattaaaag
     8461 attttatttt taatttagct acaaaatcaa ttaaattagg aataacatat aagactgtag
     8521 acaaaataat gccaggttta attatctaat aaattttgta ttttttacaa aaaactattg
     8581 agaacataga ggttatatga tataataaaa atatattgag aacagagaag ttaaaaaggg
     8641 gggcaatgag atgactgaca aaataataat agcaagtgta gatggagagg aaatgatatt
     8701 tagaactgaa atgaaaaagt tagaaaaagg agatagtctt atagtttctg taaatggtgt
     8761 aaaaagatta gctctattca ttaggtatat aagtacttgt gaagaatata tagaagatat
     8821 agcatttcaa aaagtagatg aaatattata tgaaaacaca attgccaaag aaaaagaaag
     8881 agttaaaaag gtatttaaag ataagtgtat gaaaaattat aaacctattg ttaatacaga
     8941 aatagactct tatttgagag aatgtggttt caattgtgat ggtagacaat ttttcaaaag
     9001 tatagacaat acacaaattt taattagcag ggattgtgat aaagatgttt tgactgtatc
     9061 gaaaggtttg acaataacta aaacagatat aacaaataaa aatttaatta cagttattaa
     9121 aataataaat aatagtctat taatagttag gtaatagaaa taaatattga acttttaata
     9181 agaaaaaaga ttttaaataa aaggagtgat ttaatgaaga atgttattaa aagagatggg
     9241 aggatagttc cctttgatga aaagaaaata ataaatgcaa tagaaaaaag ctttttatca
     9301 ttaaggaaca aaggaaaaag tgaagtattt gatagagaat tagcaacact aatagctaaa
     9361 aaaataaaaa ataaaccatg tgaaaaaatg catatagaag atatacaaga tataatcgaa
     9421 tttagcttaa tggctagtaa aaagaaagat gtcgctaaag aatatataac atacagagag
     9481 aaaagaaata tagcaagagg aagaaaaact tataatgatt atatgtctat tgtaaatact
     9541 gaaagtaatg atataactaa agaaaatgca aatatgaacg cagatactcc agcaggtatg
     9601 atgatgaagt ttgcaagtga agctactaaa acttttactg accatgtact tttatctgaa
     9661 gaagcaaaag aagcaatgat ggataattat atacatatac atgataaaga ctattatcct
     9721 acgaaatcat tgacttgtat ccaacatcct ttagataaaa tttttaataa tggttttaga
     9781 gcgggacatg gctctagtag acctactaaa agaatagaga cttcaagtat attaggatgt
     9841 attagtttag agactgtaca aaatgaaatg catggaggac aggcgatacc agcttttgat
     9901 ttttataatg ctccgagtgt aagaaaaaca tttatagaag aaataaaaaa tatagaaata
     9961 aaggatgata ttgatttatc tcatttatac aatatagaaa tagaggatta tataattaag
    10021 gacttaaaag aattagacag cgaaaaaaga aatgttcaac atgctataaa cagaactgta
    10081 tggagagttc atcaatcaat ggagtcattt atacataata tgaacacaat tcattcaagg
    10141 ggtggaaatc aggtcgtgtt tagttctata aattatggta cagatacttc agcagaaggt
    10201 agatgtataa taagagaaat actaaaatct acttatgaag gagtcggaaa tggagaaaca
    10261 ccaattttcc caattcaaat ctggaaagtg aaagaaggtg tgaactataa tcctactgat
    10321 agaaattatg acttatatga attagcatgt aaagtatcag ctaaaagatt ttttcctaat
    10381 tttttaaatt tagatgcaac cttcaataag catgtaaaat ggaaaatgtg cgacccaaac
    10441 agatatattt atgaagtagc aacaatgggg tgtcgtacaa gggtatttga agatttgcat
    10501 ggagaaaaaa caagtatagg aagaggaaat ctatctttta cgactcttaa tttagtaaaa
    10561 atggcattag aggctaaaga aaaatatcca aataatgaag ctaatagagt tgcagagttt
    10621 atttttcttc ttgataaata ttcagatgta gtagcaagac aattatatga tagatactta
    10681 tttcaatgta ctgctaaagc aaaacagttt ccactattaa tgagtgggtt atggaaaaac
    10741 tcagaaaatt taaatccaaa tgatgatgta agcgaagttt taaagcatgg aacacttggg
    10801 gtaggattta taggtctagc agaatgttta atagctctta taggtgagca tcatggtgaa
    10861 agcgaaaagg cacaaaaatt aggtttagaa atcatatcac ttctaaagtc taaagtagaa
    10921 aaatataaaa agaaatataa cctcaattat tctgtattag gcacacccgc agaaggtctt
    10981 tctggaaaat ttactcaaaa agataaaaaa atatttggag aaataaaaaa tattacagac
    11041 aaagattatt atactaatag ttctcatgtt ccagtttggt ataactgcaa tgttgaacat
    11101 aaagcgaaaa tagaagcacc ttaccatgaa ttagaaggtg gtggccacat attttatgtt
    11161 gaattagatg gggatgcaac acataatcct aaagctataa tgaaagttgt ggatttaatg
    11221 aaaaagtaca atatgggata tggttctgta aatcatacaa gaagtagatg tatgaattgt
    11281 ggttttgaaa acgcagattc agagttaaaa gaatgtccta aatgtggcag caatagtata
    11341 aatattatcc aaagaattac aggttattta gttggaacta cggatagctg gaataatgca
    11401 aaattagctg agttaaagga tagagtcaca catggataaa gactatattt atattttaga
    11461 tataaaacat gacacaattg ttgatggaga agggtttaga acatctattt attgttctgg
    11521 atgtaatcat atgtgtagag gctgccacaa tcctcaatct tgggatataa aaaatggaac
    11581 tttaactaaa gtattagata tttataagga aatcatttca aataaatttt cagatgtaac
    11641 attttcagga ggagacccac ttctacaact gcaaggattt gttcatttag ctaaattaat
    11701 taaaaagaat acaaacaaaa caatatggtg ttatacaggt tttaagtttg aggaactcat
    11761 aacagacaat gaaaagctag aattgttaaa attaatagat gttcttgtgg atggaaaatt
    11821 tgaagaagat aaaaaatctt tagagttgat ttttaaaggt tcgtcaaatc aaaggataat
    11881 tgatgttcaa aaaacattgt atgaaaaaca aatagtatta tatgaataag agaggcttag
    11941 ccctctcttt ggaggtaaat gttatgacca aagaagaatt tattactaaa tttcttaaag
    12001 agcagcagag aagaataaag gttttatatt atgaagttga aaatttcaag atggatagaa
    12061 ggtttaatga gaggaaaaag tctaggagac attaaaatgt ttcttttaat ataaggagga
    12121 agtagctata tgtattttga aacggacatt ataaaaaata agaatactgt aaataaaata
    12181 ataaaatatt gtggtggaaa tactgaaaaa ttgaaagatt ggctaaaaga aatagaaaat
    12241 aaaagtatca gtagtttaga agaattaaaa gaatatccat taaaaagaaa ttataaattt
    12301 gtattttcca aagaagaagc tcctaattta gataagctta taaaaatgaa actaagagat
    12361 aattgtttag aaaaatgtga gatttgtagt ttagaaaatc tcttaagtat gctaaatgat
    12421 gagattttag atttaaataa agaagatatc tcttatgaag ataatattga atggattgaa
    12481 aattgtaaag aagaactaat taaattaaag gtaggaagta tttgcataga ttggtagaaa
    12541 aataaaggag tgatactgtg agattttggt gtgagaattg taataaatac ttcaatgtag
    12601 aagaaacatt acaagaatac tattatttct taaatgaaga tgtaatagta tgtcctagtt
    12661 gcaaaagaga tttaatacct atagctagta aaacggaatt atccttaggt tctgatagtg
    12721 atacaaacca attagcttat gttgaatatg attgtggtga ttatagttta cttagaaagg
    12781 taaatgcaga tattgaagat gtagtaaaac ccataataca ttacataaaa agtttaaata
    12841 aaaatagttt agatttaaat gggattacag aatagtgcgg aaagcccact cctttaggtg
    12901 tgggatggat agcacaaaca gtgtataaaa agtattgaca catacacgta taatgttaat
    12961 actttgtatt ctgccctaga tataaaagaa aaatatttaa tatagaaggt ttagaagata
    13021 gatttaaaac attagttaaa aataagtgta aggaaatgga tatcgaaatt gttgcaatag
    13081 aatgcgataa agaccataca catatgtttt taaatagtct tccgactcta aatccttctg
    13141 atataatgca aaatataaaa ggctatacaa gtaaaatatt aagagaagaa tttattgaat
    13201 tatcaaaaat gcctagttta tggactagaa gctattttgt atctacagca ggaaacgtat
    13261 gtagtgaaac tattaaaaaa tatgtgaaaa accagaaaac aagatactag aaagtgaggt
    13321 gaacactatg tcaaattata tattaacatt gcaattaaaa acagaaaagt ttcaagaaga
    13381 cattatatgt aatgcttttg ataagtatag aaaagtatat aattcatgtt tatcagagct
    13441 atttaaaaga tataaccaca tgatagaatc taaagaacac caagcaaatt gtaaatataa
    13501 gggtaaagat agaaataaaa tatttagtga aattaataag aagtataatt taacagagta
    13561 ttcacttcat aagtttgtta aatttattgg taaatattat aaactacatt ctgctataac
    13621 tcagaagata gctacaagat gttttaatgc ttttaataag tatatctatc atcaagctaa
    13681 acgagttaat tatattagat ataatgaatt aacatcaata gaagggaaac aaaattcaac
    13741 tggtattagt tataaagatg gtattattaa atttaataag atgactattc cagtaataat
    13801 aaagaataat gacaattatg ctcaaagagc gatacaagat aaaataaaat attgtagaat
    13861 acttaaaaaa gaaattaagg gtaaaattaa atggtatgta caattagtct tagaaggaat
    13921 tccacctaaa aaaacaacca atcaaggaaa aataaaagga caaattggtt taggtaatgt
    13981 aggtatagat attggaactc aaactatagc tatatctagt aaatgtgatg ttaagttatt
    14041 ggagttagct cctaatgtta ataatataga taggcaaata aagttaattc aacgtaaaat
    14101 ggatagaagt aaacgtgcaa ctaatcttaa taaattcaat gataatggta ctataaaaca
    14161 aggaaataga gataagtgga tatttagtaa tcactatctt aaattaaaaa gactaagaaa
    14221 agagttatat agaaaacaag ctgaaataag aaaacaagac cactatatat taattaacaa
    14281 attactaaat ttaggcaata agttttatgt tgaaacgatg agttataaaa gacttcaaac
    14341 tagagtcaag gatactacta ttaatgaaaa aactggtaga attaataaaa agaaacgttt
    14401 tggaaaatca ttagcaaata aagcaccatc aatgtttttg actatgttag acaataagtt
    14461 aaaatataat aatgaaagat tatataagat agatactgct aaatgtagag ccagtcaata
    14521 taatcacttt tcagatgagt acaataagaa ggaattaaaa gatagatgga ataatggtat
    14581 ggacattcaa agagattgct attctgcatt tttaataatg aatgttaatg aagatttaaa
    14641 atcaatcaac agagaattgt gtgttaaaac atatgataac tttaaaatat tacatgataa
    14701 agagataaat agattaaaaa aattaaaatt aaatggttat aaattaatat ctagtatggg
    14761 gatataaaaa ctatataggt tgagaaacga gcctaatatt aatgttaatg gtgtcaacag
    14821 atactttgtt aataaaagtc ttagggaata tgattagtga taatatgttg taggttatga
    14881 tttattataa ctgagagtat tgtagaaatt catgtagtac ctaagaaccc cacgccttta
    14941 ggcgtaggag tttcagaata acaatgaatg gtaatatata agaataaaaa gaaggatatt
    15001 ataagagatg agtcgatgta tgattatggg atgtctttgt catctattat gaaggttatc
    15061 ttaaatcatc aagaagatat agaaaagtta aaagaagagg aggtagcaga atttataaaa
    15121 aataaattag aaaatgagca tgattgtgat gaattaaaaa taataagtga ggtatttaat
    15181 gaaatatatt aaacatgtag ataatggagt aatgagagca ataggtattg ataattataa
    15241 acctttatta aacatcataa aagaaaaagt gaatttagaa tctaattaaa acagttttaa
    15301 ttagcgaggt gatacatatg ggattagatt taggttttta ttcagtaaaa acaaaagtta
    15361 cagatttaga tatttattta aataaaacaa gaggtgagaa atataaggaa ttgaataatg
    15421 atgaagaaga gttttataag tttgaagaat tattagatat tgatatatct ttagaagatt
    15481 ggtcagttat tcgtatgata tataaagcca aatgggaaaa aggttatgaa agttatgaag
    15541 atgaagccat acttattaca aaggaagatt tggaagatta tataattcct tttcttaaac
    15601 aaaaagatat aaattctaag atatacaata aggataaaga gtattattat aaaaatgata
    15661 aaaaagtaac agttgatgat aggtatacac aggagttttg ggatttagta ttaaaagaat
    15721 ttcaaaaaat gttaaacata attgattttg aaaaacatag tttaattatt atgtattggt
    15781 attaagataa taattttaat ttatttggag gtttataata atgaaaaaaa tgtacatagc
    15841 aattaattca gacttaaata tgagtccagg caaagttgga gcacaagttg cacatgcagt
    15901 ttatgattat ttgtataaca aaattttaga cactgtttct tgctcttatg aaacagaaat
    15961 aatagcacat gaattaatag atttaaaatg tgatttaacg tcatttaaga ataatgggga
    16021 tacaatatgt atattaaaag ctaaagaggc acaattatta aaatttaaag aaaaaggtta
    16081 tttaactata gtggatagag gattaacaga aattcctaaa aatagcataa catgtgttaa
    16141 cttaggaata tttaatgagg atgaaatacc atctacaatt aaaagattga gattatatta
    16201 aggagaaaga caataaatgt attctaaagg tgatgtagta aaagtatggt gttatcaatg
    16261 tgaaaggata gaatttcaag aatttgtagg atattttaat tcttattttg ataattataa
    16321 attaaagaaa cgatggaaat gctctaagtg tgatgtcatc aataattttt aagagtttaa
    16381 ttaatggagg aatgagttat gaaaataaag aaaataattt taggattaga taacttagag
    16441 aatgtagagt tgggtattgg agatgtagga ggtttttatt tagataatat acatgaaatt
    16501 attggaggat ttgctttgag ttatataggt aaatgcaaga aggcagatta tttacatata
    16561 caaatacata aacgtgttga tgaaattcaa agattgcatg attataagga tattacaaat
    16621 gtaaagatag aatacgaaaa cggaagtgtg gaggatatat atgtacctta taaacaagaa
    16681 ggggatttct tgggtttaga taatctttat caaacttctt ttattagtaa acgaggttat
    16741 ttacatatag ttatctctaa ggataaaaca gtagaagaag tcttcaatga agaatttgag
    16801 gatgatgaag gggtagaatt tagttttaat atgtatggaa tataaaactt aaaatggaag
    16861 gagatgagca aatataatta actcttttaa gaaattaata aagtcaaaat atataaaaaa
    16921 taacgaatca ataaaaccat tagaaagaat ttttgaatat gaaataagaa tcaaagaaaa
    16981 aagaacatat tttaatttag aattattgat ttatgaaaaa agaattaaga taataaaaaa
    17041 aatattttta aaagatatac tatgccatta tcgaagagat atagaacaac tcgtcattta
    17101 tgacctggat aaatatctta atatgacaga taaagaaatg gaggaatata ttataaattt
    17161 aataaaagat aaaataaaag aagagtatgg ggagaataga cttcctgaaa tactaatgga
    17221 aaaatttata aaactcgaaa gaaaaggttc ggtgactgta gacgtacagg atttaataga
    17281 gggataataa ataacaagtt aaaatacagg ttttaaaagg agaataacaa atggaagttc
    17341 aagggaaata taacaaagct aaaatattta cagagaatgt agattcgata acaataggac
    17401 aaataataaa tttatgtaat caaaaggaat ttaaagaatc cagtataaga attatgcctg
    17461 attgtcatgc tggtaaagga tgtacaatag gaacaacaat gactataagt gataaagtag
    17521 taccaaatct ggtaggggtg gatataggtt gtggaatggc tactattcca ttagaaaaat
    17581 atattaataa tataaattat acaaaattag ataagattat aagagattat attcctcatg
    17641 gatttaaaat acataataag tcaagagaaa aactattaaa gaatttattt aatatagaca
    17701 taaataatct tagatgcgag gtgaataaaa atagagcata tatgtcgtta ggaactttag
    17761 gtggaggcaa tcactttata gaagttgata aaagtgaaaa aggtcaaatg tatcttactg
    17821 ttcatacagg ttcaagaaat ttaggaaaac aaatagctga ttattaccaa gacaaagcta
    17881 taaaatattg tattgaaaaa tataaaaagt catatgatga tgcaaaagag tttttaatat
    17941 ctactctaaa aaaagacaat aaagaacatt tgataaataa atatttgaaa gaccttagtg
    18001 atagaaaatt gaataagcca catgatgatt tatgttattt agaaaatgat ttaatggaag
    18061 attatttaca tgatatgagt atagctcaaa aatacgctgc tgcaaataga atggttataa
    18121 ttgcggatat attgtttaaa tataacagcc tagatgtaaa ttatgaccat tttataagag
    18181 atattaaatg tgatgttata gaatgtattc ataactatat agatatggat agtaaaatac
    18241 ttagaaaagg agcaatttct gcaaataaag atgaaacagt aataattcca gtaaacatga
    18301 gagatgggat tatattagga aaaggtaaag gtaattctga gtggaattat tcagcaccac
    18361 atggagcagg aagaatttta tcaagaggaa aagctaaaga aaaaatatct ttagatgaat
    18421 ttgaagaatc tatgaaagaa atatttacaa cttgtgtagg tcaatcaaca ctagatgaag
    18481 caccacaagc atacaaacct atagaggaca tattaaacaa tataggagat actattgaga
    18541 taatggaggt gttaaaacca gtttataatt ttaaaagtaa ttaaaatgaa aaatttaata
    18601 gatgaattta ggaggaaata ctaatgggaa tgtatacaga atttgtatgt gcgattgaat
    18661 taaaaaagga tacgccaaaa gaagttatta atatattaaa taacatgata gaaggagaag
    18721 atagatatga tattacacca cctcacccat tctttgaatg tcgtagatgg agatggttat
    18781 ttataatgga tagttattct ttctcaggta ggagcaatac gatgtttgag tatgacgata
    18841 tagcaaaaac atattattta actattagaa gtaacttaaa aaattatgat gatgaaataa
    18901 ataaattttt aaattggata aaaccatata tacaaataca ttgtgaagac gatgaatttt
    18961 taggatatag tcgatatgaa gaatgtcgta atccagaatt aatttattat aatgaaatac
    19021 aataaaatct taattttaaa tggaggtaca tatgaaattt gaagataaca tgattaaatc
    19081 ttttagagag gttagagttg gagacattat acttgcaggt aataacaagt atttaataat
    19141 atcaatatta aattattttg gatatgtgaa cttagatact ggtgattgta gttctggctt
    19201 tagatcaatt gaagaattaa tgaaacaatt cgataaacaa acacgattta ttcaaaatga
    19261 tagatttaaa ttaatactag attaatataa cataaaattt tatttttata agaaaggtaa
    19321 attgaatatg tgtaagtttt gtgaaagtat aattgataat acaaaagata tacttttaac
    19381 ctcaagaagt agattattag aagacaatac atgtgaaatt atagcagaag ataattgtaa
    19441 taattgttat gatggatgtt atgaatattt caaactaaac ggatataaaa tcaggggaaa
    19501 tacatatgtt aatgtcgact actacaaaaa aattagaaaa ataataattg ctccatgttc
    19561 agaatcagta catataaact attgtccata ttgtggtaaa caagtttcta aagatataaa
    19621 agattttaat tgtattcctg agcatatagt agatgttaga tataaaaatg gtgatgtata
    19681 tgattatgat atggaaaagt ctgtacaaga agtcatggat aatgcaaata ataattaaat
    19741 aaaatgatac ttttaatagg ggataaatat gaatctttgg tctaaaattg aagaaccagt
    19801 gatgagagca gtaagtggaa tagtatttaa tatatgggga aatgtttgtt tttccatata
    19861 ttacatagaa gaaaataaac aaatagagtt agaaatatat gatagacctt atagatatga
    19921 aggtaaaaaa aatagttgtt gagaagttat ttgattacaa gttaataaat gcagattata
    19981 aagaaataca tgatattgtt tctatgatag aaagattttt actagaaaat tattaaaagg
    20041 agatatttaa aatgaataaa ggaattaaaa actatataac agcagtgaat tacttacttg
    20101 ataatttaga gtatatgatg gaggatgacg aatttaataa tgaaaagtta cagaaaagaa
    20161 ttgatgtaat tagaaaattt gaaagagaat tataagatgg gaaaaataaa aaatggagaa
    20221 atagatactg aagattatag gctttttaaa aacattcaaa aagaaaaaga tagagtatat
    20281 agtaagtaca ttaatgaaga atacataatg gaagaactca taaactactt aagattggaa
    20341 gataaagatt atactacaga aatattagaa agatatgcac gatatattga tgaaaattta
    20401 gacaatcgtt gtccatattg tgtatataat atttgtagtg aacatgataa ttgttttgat
    20461 ggaatacttg aaaatttaaa agaaaaaatt aaaataaaat aaatatttta acaggagaaa
    20521 aataattatg aaattaataa atggggatag atgtagtgga aaaactacta cattaataaa
    20581 gtatgcttat gaaaataatg cacttatatt atgttattcg tgtggaaatt tgaactatat
    20641 aattgaaaaa gcaaaggaat tgaaactaga tataattata ccaagagtat ttaaaactta
    20701 tatagagtct aatcataaaa tagaatatat gaaaactata aatggaaata ttatcaacga
    20761 tacttctaat ataagattag ttatagatga aatagattgt tgtttggaat ctattattag
    20821 agaaggtata gattgcgtca ctggaacaat tcaaatagaa aatttaaata atcatatctg
    20881 ataaatttgt ttattacata tcaaaaaatt ctaagtgttc ttatttacaa ttcaattaaa
    20941 actaaaggag tgaaattata ttgaaaaaaa ttttattaat aggtgcatta ggaacaatgt
    21001 taataggaat gtctggatgt acaggaatac aaagctcaat gaaagatgct gaaagtgatg
    21061 tatcaggtct taatagagtt gtaaatgtat attcagataa tggcgaggta ttaaaaacat
    21121 atacaagtaa aagtatgaga gtcaaagatg gagatggtgg cactataaca ctagattttg
    21181 atggtaagag ggtgattata tgtaatgctc atgtagtaat agaagaaaat caatctaaca
    21241 aataaaggag aactaaatgt ttaaagtctt aaaaacaatt cttataataa tttgggtagt
    21301 agatatttta aacttcccac aatttcaatt cttagataca acatatccaa tcaatacctt
    21361 agcatggttg ctaatctgga ttcttatacc atcaagtagt atatatattg ataaaaaaga
    21421 ataaagaagg gagtattagt ttgattttaa atattggtgc aatttttaat ttatggtgta
    21481 tgttagctaa ttatttatgg ggaagtacta gtggaatgat acttaatgga ttttgtctta
    21541 tagcattact attattggat aataacttag attaaaagta ttattttaag gagattaaaa
    21601 gatgaaaata acaatatcaa ttgaagaagc aatggatatt attaaacagc actatgagaa
    21661 taaaggaatt gaaatcaaag acttaagttt taatttagaa aaaactggaa tggttagaaa
    21721 tattaaattt aagggagaaa taatacttaa gtaggagata tttatagttg catcagtaaa
    21781 taaaatatta gacaaataga ggtgatactt ataagtagta caaatagaag taatgctagg
    21841 gattttcatg taagtgatta ttatagaact ccaattacta aaatcaaaga gtttttaact
    21901 gagttcagta gatatgaaaa tatactcaat ccaaatataa aaatattaga cccatgtgca
    21961 ggtggagata atacaaatcc aatgagttat ccaactgcaa ttcaagaatt tttaaatcaa
    22021 gatatttcaa tagatacagt agatataaga gatgattcaa gggcaaatat aaagcaagat
    22081 tatttaaagt ttcagcccaa agaaaaatac gatgtaatta ttactaatcc tccctttaat
    22141 ttaagcttgg atataattaa taaagcttta aatgatgtaa gagaaggtgg tttcgttatt
    22201 atgctgctaa gattaaatta tcttggagga aaagtgagac aaaggctgtg gggaaataat
    22261 atgcctaaat acatatttgt tcacaataga agaatgagtt ttacagatga tggaaagaca
    22321 gatagcatag aatatgctca ttttgtatgg cagaagggat ataatccaaa attttctcag
    22381 ttaaaagtat taataagtca atgaaataga ggtgtaaagt gaaagttaaa tacgttgtat
    22441 ttgaatggga gattacatca aaaaatgatg gccaaaaaca ttttataaat tttagagatt
    22501 taattaaatt atatggagtg tcgtcaagag aatgtataag agcaaaggat tattacgaga
    22561 gagatggttt agaccttaaa gatataaaat ttctatatcc aagggatgat ggaaaatata
    22621 aactataaaa tcatggtttt aaatgattat aaaatgtcag ttttaaaggg ggctaatcat
    22681 atatggatat taagatagat atgtgtttat tagagatgga aataaataga agaagatgtg
    22741 agtatgctgc cagaacagga agatatccta attctcttat tttgtgggaa ggttactata
    22801 gccttcttaa tatccaatat atagaggata aaacaagagg atatattact aaatttaatg
    22861 gcatggatgt tataaaatgt aatgattttt taaaaataga attatttgaa aagaatatta
    22921 ataattaaaa tttgtttttt aagttgaggt gatgagttga gatataataa ttatcatagt
    22981 cataaaattt attcaaatat aaggtcgtta gatgtaatta ctaaaccaca acaatatata
    23041 gatagagcaa taaaactagg tcaaaataca tattttacga cagaacatgg atatcaagga
    23101 aatgtatatg aggcaaaaac tttatgtgat gaatataaat taaaaatgat tattggagca
    23161 gaattttact atgtaaatga tataaatgag aaagatagag gaaattatca tttaatagta
    23221 atcgctaaaa ataatgatgg ttacaagcaa ataaataaag ctttaagttt agctaataaa
    23281 aatggatatt actataaacc aagaatagat gaaaaaatat tatttgagat atttaaacca
    23341 ggggatgtag ttattactac tgcatgtgta gctggaatat taaaacttga gaatagagaa
    23401 gaattaatac taaaactaaa gaattatttt aaaaataatt tctttcttga agtacaatct
    23461 catcctcata aaactcaagc tttgcacaat aaggatgttt tagaattaag caacaaatat
    23521 aatatagata taatacacgc caatgacagt cattatattt atccagaaga atcaaaatat
    23581 agaactaaat ttcttaaagc taaaggtata aattatcctg aagaagacgg ttttatttta
    23641 gattatccaa attcagagga tatatttaaa agatatgaaa aacaaaatgt attaacaaag
    23701 caagaagttg aaagagcatt aaaaaatact ctaatatttg atgagtgtga agaaatcacc
    23761 ttaataaatg atgatataaa attaccatca atatctaaaa atccaaataa agaactgaaa
    23821 gaaatattaa ataaagaatg gttagagaaa agaaaaaata tacctaaaaa tagatggaat
    23881 gaatacttag atgctataag gtatgaattt gatattatag agaaaactca tatggaggat
    23941 tactttatta tagattataa aatagttcaa agagcaaaac aagaatataa tggtcttctt
    24001 actaaaacag ggagaggttc agcaccttca tttataataa ctaatctttt agggcttact
    24061 gaaatagata gattaaatgc tccggtacca ttattcccta ctagatttat gagtgttgaa
    24121 agaatactat cagcaaaatc tttgccagat atagatttaa atgctgaaga tgctgaacca
    24181 tttatacaag caactagaga tttattagga gaagaaaatt gtgcatggat gataagttat
    24241 aagccattac aagatgcttc agcttttagg ctatggtgta aagcaaatga tatgaaacta
    24301 tctgagtatg atgaagtagc taaaaactta gataaataca caaatgatgt tttttggaaa
    24361 gatgtaataa aggaatcaaa ggtatttgta ggagtagtag aaagtgtttc tttctcacca
    24421 tgctctatgc ttatatatga tagaccaatt gatgaagaag taggattatt aaaaactaag
    24481 gatggggtat gttgtaatat agatggatat tattgtgata agtataaata tttaaaaaat
    24541 gattatttaa cagtgaaagt atggtcatta ataagaaaaa tttgtgaatt agcaaatatt
    24601 agtattccta caattgaaga actaaacatc ttattagatg ctaaaaccta tgacatatat
    24661 aaggacaaat taacttgcac tataaatcag gtagattcag actatgctac aaacctggca
    24721 tctaaataca aaatatctag tgtggcggaa acaagtgcat ttgtagctag tatcagacca
    24781 ggatttgcat ctttattaga caattttatt aacagagagt catatacaac taacgttaaa
    24841 gaactagata tattattaga agatagttat cattatctta tgtatcaaga atcaataatg
    24901 aaatatttaa tatggttagg aatagaggaa tctgagagtt atgatattat aaataagatt
    24961 aaaaaaaaga gatttaagga aaaagagttg aaagaattgc atatcaaact aaaaaataac
    25021 tggattaaaa aagtcggaac tgaaaataat tttgaagata catggcaagt tgtaaatgat
    25081 gctgcctcat attcctttaa tgcttcacat agtctttcat atgcatatga cagcttatac
    25141 tgtgcatacc ttaagtcaca ttatccattg gaatattata ctgtagcatt caatttatat
    25201 aatgaagata cagagagaac aagaaaatta acagatgaaa tagagtattt tagtattaaa
    25261 ttagaaaatc ctaaatttag attttcaaaa tctgaatact tctttaatag agacacaaat
    25321 agtatttaca agggcattga atctattaaa tttttaaatt ctgatatagg agagtatcta
    25381 tattctctta aagataataa atatgattca tttttagagc tattaataga tttgcagggg
    25441 catataaact ctaaacaatt atctatactg attaagctag atttctttga ggaatttgga
    25501 aagtccaaca aacttttaga gacttatgat atctataact caatctatag taaaaaacaa
    25561 tttaaaagag ataatttacc atgcaatata aataccatga gaaaatactc taataaagaa
    25621 acagaaaaaa tatttaaaga agttgataca aaagaattat gttcttatct tgaaagtcaa
    25681 attgaaaata cagatatacc aaccaatgaa aaaatacaag ctcattttga gtttgtgggt
    25741 tcatgtaaca taaaagatag caattcaaat ccaagatatt gtttagtaat agatatagat
    25801 actaaatatt ctcctaaagt cacattgtat aatataagtt cagggaatat aaagattttc
    25861 aaagtaagta aacctatttt tgaggataat aaaattgatg tttatgattt agtttattta
    25921 aaatcaatta aagaaaaagc taaaagtaaa aaagtagatg gaaaatggat taggagcaat
    25981 acagaaacag aatggtggat acaagaatat tggaaaatag aaaattaaga atatgacctc
    26041 gtatatgcgt ttctaagact ttacataaga gtctgcttgt gtttatacat tgatttctta
    26101 aaatggcata tacgaagttc gtgaaaggta gtgatttcaa tacttataga tgaacaaaga
    26161 tattatagct tattggaaga aaaaaaagac ctaagtatga gaatcgatga attaaaagag
    26221 gaaaatgctt ttttaaaaca agaaaatgaa gagtatgaag aaattcttaa tgagtgggaa
    26281 tgtgtaagaa aagaaattgt agcaacttgt aaaaaaaaag aaatattagg tgaaaaacca
    26341 agtgaattag aaatggttct tcaaaaaata gaggatatat aatgagtgta aataaaattt
    26401 atgagaaaaa agaatacatt attatcaaat caaaatctgg atatatagtt tataatacaa
    26461 ataaagagtt taaagaaggc cacactcact taaaaagtta taatgctgct aaaacagcta
    26521 tagatttagt tattaagaga aggcttccta aaagttattc tatttatttt cttacaagtt
    26581 tgatgagaat atctaatgat gtacaatata taaaacatat aagcgatatt gtatatataa
    26641 gaaataataa aggactaaaa gaaaaatata taaattctaa aaatattaaa aaaaactatt
    26701 gagaacatag aaggtatatg atatactatg aatataacaa gaacatagaa ggtaaaaagg
    26761 aggtagtgat taatatttga aatcttataa agaaaaacag tttttagtat ttgaatttga
    26821 aaatgggaag aatgtaaagt ataatttggc aacaggagaa tacgttggta aatctggaag
    26881 gattgtaaaa gatgtgtgta ctcaacttag aggatataat ttacatgagg taataaattc
    26941 ttttgaagat gaaaattata agtgtttttt aaattttgta gatgaaagag taaatagaag
    27001 taagagtagc agagcttggg gaaggagggt tgaaagaata agaaatatag gaagtttttt
    27061 aaatgaaata aataattatt ctgagtatga acaattattc tcagcaggat taaaaaaaat
    27121 aatttatccg atacattgtg atattaagag tatacctaaa ggtcttattt ctatctgtag
    27181 gaattatagt attactttga gtgaccgatt gatacaaggg tatagtaaaa acccaaattt
    27241 gtataataat ttattaagtt tagaattgaa ttcaataaga aaaactaatt taatttcaat
    27301 tcttgattct ggttatgata gaatgatatt tgatagatta atagacatat ataaatataa
    27361 acctcaatca cttataaatt atatagataa tctgatgaca tatgaagcat taaatgggct
    27421 tgaaagcact ctaaacgaat tatatgacta tgttgttatg atgagtgtaa taagtgataa
    27481 atatgaaaaa tatccaagac atttcttaac aactcataaa atagcatctc gaaattataa
    27541 tcgtcttaaa actcaatttg aagaagaagt atttaataaa aggatagaca agtcactaga
    27601 atattcatat caagattata aatttatata ccctaaaaat acaaatgaaa ttaaagatga
    27661 agcagtacaa caaaataatt gtgtaagtag ttatattcaa aatgttatag atggaaaatg
    27721 tcatatatta tttatgagaa aaaaggataa tccaagtaaa agtttagtaa caattgaagt
    27781 tagaaatggc aaaatagtcc aagctaaagg taaatataat agagatgtca atgaaagaga
    27841 gcaagaagca attgataaat ataataatag aatagaaagg atgaagaaaa tatgttaata
    27901 gaaagaacta aaataagatt aatgaaagaa atacaaggtt ttgagatgtt aaaaatagga
    27961 gatatatttg ttattacatc tgtgggaaat aatggagcta tacattttaa aacagattat
    28021 ggaataggtt ttatgaacta tagtgaattt gaagcatatt ttgaaattgt tcaacaaaag
    28081 aaaaaatatg aatggggtgc atggtctata agaggagatt tctctggagc atatctatat
    28141 agaacaaatg ggaaaaaagt agaagttaga aaaggaaatt ttaaagcatc agctacttgc
    28201 catgattcag atgagtttga attaaataaa ggtgttgagt tatgtctggc aagaattgaa
    28261 gttaaaaaag caaataaaca ggtgaattta gtattagata aaataaataa taaagaaatt
    28321 taggaggtta gaatgatttg taaatttaaa gaaagatgtg aaaataaaaa tagagattgc
    28381 gattattgtt gttataatcc aaatgcatat ttagaagatg cttttgaatg gaatggagaa
    28441 gggagaaagc caacagacga agagttagat gatgctcttg aagaataaat aagtatttaa
    28501 aattatcatt ttaatataac caggaggtat ttatggaagg gataataaat agacctgtat
    28561 ttgatttaaa tacatttttc actggaagtg caataagtta tggttacaga ggaaatagta
    28621 aacacaacgc attaatatct agtataacac catttcaaat agatgtggcc tatatcagcg
    28681 gaaataaagt agaaagtgat attataagtc ttcatcatgt tttagatgga caaatagaaa
    28741 tagagttatt aaaattttaa gtgaatttaa agaaaagagg tatatatgag gtggaaaaac
    28801 atattagtaa caggagcttt aatagttggt agtacaatac atgtatttgc taatacagaa
    28861 gatgttgtta ataataatat aaataaagaa cttatagcag atacagcaag gaatattaat
    28921 ttaatgtata aaaaagaatg ggagcaatat aaaaatacta aagaatataa actagaaatt
    28981 aaaagaatta atttagaaaa agaattagaa ataaaaatag aaaaactaat tcctatgaca
    29041 tggaaagtaa gttattacac ttctttaaat tgtgagaata gtagatatgg agctgttaca
    29101 gcaacaggag aaaaattaag atatggattt gtagctaata atcatcttaa gtttggaact
    29161 aaaatattag ttgatggaaa tttaaaggta gttaaagata gaggttctaa taaatatttt
    29221 ggaaactcta atgcaataga tgtatttgtg ccaagaataa aaggggagag tgattataaa
    29281 tattataaga gagtaaacaa catgggaaga cattataaag aaggatatat tatagttgaa
    29341 ggttaggagt tgataaattg aaagtaaatg gaataaaaat accaggaatt attgatgtat
    29401 caaatgtgtg tgtttatgga attaaagaaa gtataatttc gagtggttat cctatgcagc
    29461 aacagattaa agatatgaga gaagtaaata tttcagaaaa agatttacaa cgagcatgtc
    29521 aattaggcaa atcaaaacaa ggttcaggcc atgattgctt ctctaaagga attattgttc
    29581 aaatggattt gcaatggtca gaatatatgt ggagacagtg ggatagatat catcataatg
    29641 actatgtatc tagtcaaagt aaaatgcaca gattaaccaa atttaatatt gatgatatgt
    29701 gtaataagta tgttgttaaa aatacaataa atttcctgaa tgaattgatt tacgattata
    29761 ataattttca ggaattaaaa ttaaccgcat ctgatgaagt cactcttaga aatggagaaa
    29821 atattagagc cacaaaggaa actctttgga aaattataat atcaaattgc ccatcaggat
    29881 taatgttaac tgcaagagtt acattaaatt atctacaaat aaaatctatg ataaatcaaa
    29941 gagaaaatca taaaatggaa gaatggagaa ttctgtgtga cttttttaaa acactaccaa
    30001 aatataaaga attaatgatg taatagtttt gttagcaatt aaattttaaa tataaaggag
    30061 aagtgggtat ggcagaaaaa agaataaatt ataatcaagt atttgtatca ggagaagttt
    30121 tagacatttt aaatatagct agaatgaatc aaggaactgg ccaagaagct ataagattta
    30181 ccttaaaggt tgaaacagca ccaaacgaat cagtaaatgt agattacttt acatcaatgt
    30241 ttaagtcaga tggttcacca aatcaaatgt ttttaggaat agagacaata gctaatgaaa
    30301 taaaaactag agcagaagat ggaaaaggtg atattgttag atgtgtttgt tcattagaca
    30361 ataacttata ttataaagat ggtgaaaaga aagagcgatt ccaaatatca ggaacttttt
    30421 gcaatagaga aaaatatgat gacaaaggta atcctattga tgacaaaggc gaagtagtaa
    30481 agtcaataaa agcgagtcag gtctggagag tatatacatt aattgaaaat atagaagaaa
    30541 aagaagatga tttaggtaag tatttagaga ttaagggttt aattaataaa tatggtaagc
    30601 aaggttgtaa tatgacattt agaatacata atgaagatat gatagaagga tttaaaagtt
    30661 tatataaaat aggagatgtt ggccttcttg aaggtacagt aaaatctatg gttgttagta
    30721 aatcagcagg atttggttca agaattaaaa aaagtgcttt tacattttta gaaatagaag
    30781 gtggcgatga acctttgaaa gatggagaca aaatatttag tgataaaaat tatcctttca
    30841 cagataagaa tatagaggca atgagagaaa aaataaaaga aaaagatgaa aaagaaaaac
    30901 aaagagatgt tgataaaaat ggtaagacaa ttgagataag tgatgatgat gtaccatttt
    30961 aaattataaa ttaaataatc tattaaaaag gagagatgtg aatggaagtt aaagaaaaaa
    31021 caatgaatga tggtttcaag aaagtggtaa atgaggaaat aaagacgtat atatcaaatt
    31081 tatattcaga tagaatagac ggattaaaag agagtgatag tcaaattgag ataacaaaag
    31141 cattaatagc ctttcattta gatatagaat cgattccaaa ggataataca aacccatttt
    31201 tcaggtctaa atatgcaaac cttgatacaa ttcttaaagc agtaaatcca ttattagcaa
    31261 aacatgattt aatactaatg caatcagcag aagatgcagg taatgataaa gtatatataa
    31321 aaactaaact aaagcattca tcaggcgaat acatagagtc aaattctgca ccatttaaac
    31381 cagctaaaac taatgatata caagctagag gagcattgga aacttatttg agaagatatg
    31441 cagttcaatc agtattagca ttatcattcg aggaagacga tgatggaaat tctttaacaa
    31501 acaaatcaaa gggtaaatca gaggaagaaa attcaactat taagaaaagt agagtgtaaa
    31561 taaaattgct acctcttaaa tgaggtagca ataaatacat aacataagga ggggaaatct
    31621 tgaattgtaa gtgtaggttt tgtaaaaaga aattaaatac aaatgatgct tataaagtag
    31681 agcatattac atctggggga aataagcaga atagatatta ttgcaatgaa caggaatata
    31741 gaaaagagca acaggatata tatttctgga aacaatgtca acttggaata gattatatta
    31801 tgggatatac agttataaat aatcaaaaaa ataagatgtt acaagagata ataaaaggtg
    31861 gttatacgag agaagaatta tatgattgca tcattgagaa gaaagatgaa gttatagaat
    31921 tacttaacta tagaaaagat atagaagaag aatatcctaa attatgttat gtgtttacaa
    31981 tattgaaagg aagtattaga gatataacaa ttaaaaacaa gcaaatgaaa tatgaaaaag
    32041 aaaatgaaag gatatacaaa gaagtagaga aaagtgaaga atattatgaa ataattgctc
    32101 ctaaaaaagt aatttataat aaaagacaaa gtttatttga caaagtgaaa ggagtgtatc
    32161 aagacgagta gttatgaaaa aataatagag gataggggta ttatagaaac attggtttta
    32221 ggcacaatgt taaaatcatt aactcttttt agtgaatata aaattagcga aagtgacttt
    32281 ataatagata aggtaaaatt ctttttctcg ttaggaagaa taatgtctaa aacacataac
    32341 gagcttgatg aaataagtgt agctaaattt gtatcttcaa ataaactcaa atctgaatat
    32401 gaaagatatg gtggttggaa tagcttatca tctgctatgg agtatggaaa agaaactaat
    32461 atagcagcat atattgatga tttagctaag aataatttac taattgcttt agataaaaga
    32521 ggttttaatg taataaaaga aatggagcat aatgggttaa aatttattcc atttgaaata
    32581 tttcaatcta tgaaatgtag agaagtggaa gaattttatg aggggttaat atcttcatgt
    32641 agtgtaaatt ctataaaaaa taatatgaaa gttgaaaatc ttttacttac taaagatgat
    32701 agagaaaaat taaagcaaaa aactgaagca ggaacacctt ataatattat atttgaatac
    32761 actgaaaaag aaataggatt gagtaataat gaagaatcta agtatatata tagcttacca
    32821 atattatcaa ataggactaa tgggattggt aagggtggtg gtataaatat aatagcaggg
    32881 ttttcaggca taggaaaaac tactttacta ttttttaatt acatattagc tatgatatat
    32941 agaggagaga agatagtcat atttgcgaat gaacaaaaat ctcaatattt taagagtatg
    33001 ttagtatcgt ttatagcata taacatattt aattatcatg atttagatag aaataaaata
    33061 gataatggag attttacaga ctttgaagaa gacttaatgg aaaaaataga aaaattttta
    33121 agagatagat gttttgcaga gaatctaaaa tttatctata tggaagaatt tgaaatatct
    33181 gaaatactaa ggaaaagtaa agaacttgtt acacatcagg gatttactgg aatagcagtg
    33241 gatacattta aatcagaaga ttcgtcagat gcacattata caggaaaatt aattgaaaat
    33301 tctaaattac tcgatagttt tgggaacaaa tataatgtaa taactatgtt atctatgcaa
    33361 ttacttacag ctcaagaaaa taaaagctca tatctttcgg caggagattt gtcagaagcg
    33421 aaagctgtca aaaatgtatg tggtttatta aaacttatga gaaaagtagt aaatgagtta
    33481 gaattagatt ctactaacaa gaaattcttt ttaaaaccat ataaattaaa atataataaa
    33541 ttaaaaaaga ctactgaaag agaatatatc cagtttgatg caaaagattt gcaaaaagaa
    33601 tatagattat tatttttaaa taagtcaaga agaggtcaag atggagatgt aattttacta
    33661 agattttatg gtaagactgg tagattagaa gagataggaa ggtgtgagaa ggtctacaga
    33721 ggacaattgt catactaggt gatgactatg gaaataaagg atttgactaa tgaacaggtg
    33781 ataaatttta tggaatattt aggttcggac ttatctccta aaagcaatga tagacagtta
    33841 atattcaata cttgtttatg tcataatggt gattcataca aattatttta ttatacagaa
    33901 agcaaaacgt ttcattgcta tagttcttgt ggccatatag gtagcttaat agatttatta
    33961 atacacataa ataaatatga gtttaaagat gctattaatg aaataaaaga tttctttggt
    34021 atttcaaatc aaccaatgct aagaaaagga tttagaataa agaaaaaagt agaacagata
    34081 catgatatta aagatataca aatagaatta cttcctaccc ctaaaaagcc atatgtatat
    34141 aaaacttttc agcaagtccc aattgaagag tgggaaaatg aaaacatatc ttttgaagtc
    34201 cttaaaacat atcaagtata ttataatcta tatgaaaatc aaatagtaat tccacatttc
    34261 tgttggcatg atagagctag gcctgttggt attagagtta gaaacttaga tgaagataag
    34321 gctaaaagtt ttggcaaata tattccatta tggtacgaca ataggtgcta taatcataga
    34381 ttaagtctta atctatatgg attaaatgta aataaaaaat ctatcaaaaa ttccaaaaaa
    34441 gttattgtat ttgaaggtga aaaatcggtg ttacaaatgg ctactatgta taaaaataat
    34501 ccctctgtag ctatatgtgg gagtaatttt agtagagagc aaaaaaagat attaatagat
    34561 ttaggtattg aagaattaat catagctttt gatagacaat ttaaagttaa agatgatgaa
    34621 gaatatgtta tatggagaga taagatatat aaattagttc aagatattaa agatgtagtg
    34681 aatataagtg taatatggga taaatataat ttattgggct acaaagatag tcctagcgat
    34741 aaaggaaaga caatatttga aaaactatta aaaaacagaa ttaatataga gaactttgtt
    34801 aaacaataaa aaagtaaaga aattaatttt atgagaaaat ttttattgtt tagggattta
    34861 ttagcagatg ctaaataaaa tatgtgtttt aatatgaatt ggaggtagat tacatgataa
    34921 aatttttaat aaaaaacgta cacatgggag ataaattata ttgtataaat aacataggaa
    34981 attataaaaa aggtgaaatt tatacagtga gtgatactag tttttttgga ctctttcata
    35041 aaactaaagg agaaaattgc ttaccaattg aatgttattt tatacactta ccaaaaaaag
    35101 aagagttaga aagtaatcct aaatcaatga ctaaagaaga aattgaagat gaactaggat
    35161 ataaaattaa aatagtttct aaataataaa gtgaggtgat attatattga gtatcttcaa
    35221 taaaaaatat ggtagaaatg taaaaataac agaagaagaa cctccttctc ctcctcccaa
    35281 acaaccaata tataatagag ataatataca atatgataaa gaaatggaaa gaaaactatt
    35341 agatattgat aggttaaaaa tagaattgga aaaagaaaaa aagatagaag aagaaagaaa
    35401 aaaagtagaa agagtaaagg aaaatgaggg aaaggaatgg gcttgggttg aaggatataa
    35461 atgtacagat aaaaatatga aatgtaagga atttcaatat gaattaaaca aagcctatag
    35521 tatggatggt gatgatatta atatatggaa ttggggattc catttatgtt tagacttggg
    35581 tgacgtattt caatattatg ctccaaattt aagcaataga ttttttaaag taaaagctct
    35641 agtgaaaaaa gccgataaat ataaatatgg taaagaatat ggtgaagtga ctctcctttc
    35701 aggtagtgtt ttacgtggtc ataaaataaa taaaatagct gctaaagaga taatattttt
    35761 agaagaatta acttttgata aattaaaact acatatacaa aatagttttc ctgaagtaaa
    35821 cactaagtct aaatggtatg ccatatgtaa attaggagaa caagaatatt atcatagaat
    35881 gtttatgaat caaatgaaaa agattagatt ttcagataca ttttctcaat tattatttga
    35941 tgaatgtcgt aattattgtg aaatattaga aatcttaaat aaagcaatag catattcaaa
    36001 agaaaattta tctaaagata tgataatata tttgcttatg aaagatataa gaaagtaaca
    36061 tataaaaaga agggagataa tgtggacaaa ataaataaga tagatttgat taagttaaaa
    36121 gaaatgaata tatatgataa ttatcaatta aaaaaaatag caagtaaaat gatattacat
    36181 ctaagatatg aaataatgga cttttgtggt tgtggttctc ctgaagatat atcttttatg
    36241 ataaaaggag tattgactgc catacaaaat aaagaaaaaa attgtaattt agaatacaca
    36301 gaaagatgtt acatatttga aatagaattt aataatgttt gtggaataat tggtagtaaa
    36361 aatgatttga tacaagaatt tatattaaat gctttaaatt catatgggtt attagaacat
    36421 ggtagtagca tttgggggtc atggctatct gattatggta aacaaatatt atgtgctttt
    36481 gaaatagttg gtgactgtat tttagatgtt agctatttag attaaaaagt tagttttaat
    36541 aggaggtggt aattattaaa tatgtaatga gtgacttaca tggtatgtat gataaattta
    36601 tttcaatgtt agagcaaatc aatttcaatt caaatgacca tttgtatatt ttaggagatg
    36661 tattagatag aggggataag tctttagaga ttatagatta tataagaaag tataagaata
    36721 taactcttct aaaaggtaat catgagttaa tgtttcaaga aagttataca gatgtaaata
    36781 gtagttttct ttggttttat aatggaggta aagatacatt ttatgattta ggaatgaagt
    36841 cttatgaata taaagaaaat ttttataaat atattaagaa ccttccatat ttagagataa
    36901 tagataattt tatactagtc catgctggac tataccttcc aaataactat gagaatctca
    36961 gtatagagca aataattgag ttacaagaag aagatatttg tgtgtgggat agaacaatat
    37021 taaatactaa taaacatata aaaggataca caattattat tggtcataca ccaactcaaa
    37081 acattaaaga ttatgaaaag gctgaaatat ataaacagga aggaattata aatatagatt
    37141 gtggagcatg ttttgataat ggtaaattgg cttgtttaag attggatgat atgaaagaat
    37201 tttatattta agaggtgtta tatggacata ttaaaaatca gttacaacaa tctaaatgct
    37261 atatcaaaaa tatcagaagt attaagggat attgtaaatg aggacacttt aatagtatgt
    37321 ataggtagtg atagagtttt agctgactca ttagccccta tgattggcag tatactagaa
    37381 aaatctacta ttagaaataa aatatttgga gtattaggag attcaataca tgctttaaat
    37441 ttagaacaaa aaatacaagc aataaaaaat aattatccaa attcaaatat aatagccatt
    37501 gatgcttgta taagtaaaat ttcagataaa ggaacaatta taattagcaa taaacctgtt
    37561 aaaccaggtt tgggggtaga taagaagtta ctagaagttg gtgattattc aatagttggg
    37621 attataggta gaaataaata tgatatatat gatacttcag accctgaact tatacttgat
    37681 ttagctgatg ttatatcgaa atctttaata tctatattat tagaaaaaga agaaaggatg
    37741 attgtatgat acaggaagtc agacaagaaa tactattaaa aaatggtttg attttatata
    37801 caggtgattt ggtagaaata aaatacaaat cagatgaaga tgtaatagaa catacttgta
    37861 aaggtaaaat taaagaagca aaagaattat ttattaaatt agatacaagt aagaaatata
    37921 aaacttctga aagaatgatt tattcttggg aattaaaaga aataaaaaag gtggatgatg
    37981 aagatgaaaa agataattaa tagtaaatat agagcattat atttatttat attttttcta
    38041 attttcaatt taatatatag tttatatttt ggaaggaaca cggagattgg attttattct
    38101 agtacatctt gcatagaaga atatatactg gatattataa cctctatagg actatttttc
    38161 tcaatgatgt tagctgggtt tgatgttaca gaaaacttta taaacagttt aagggattat
    38221 tgtgaaaaag atgcaaagtg aggtgaataa attggaatta aaggattata taagtaaagt
    38281 agaattaaat gatatgccac taactttaga taatcagtac atgttaaatg aaataagcat
    38341 atctgaatat ggtaaaatat ttgctgtaaa agacacatca ggaagaacat cttattatac
    38401 tgaaatagaa tttaataaac tatttagagg aattaatagc atcctagaga atattatcta
    38461 atatatattt ttaaggaact gagggttgag agctattaat taatagctct ctattttttt
    38521 gaaaggggag agttaatgga aaaggaatta tatagcttta gcaaattaaa tgcatttcac
    38581 acatgtccat ttcagtacta tcttacatat gtaaaaaatt taaatcgaga acaaaattgt
    38641 tatggttatt atggtaatga attacacaaa ttgctagaag aactacagca aagaaaaata
    38701 acaaatcaag aagctattca aaaatataat gaagttatag aatatgcaaa tctaatggat
    38761 tacaactttc ctacaccaaa ttcaagaatt aattatttag aatgtatctt acattatata
    38821 gaaaattttg taccaattga gtgtgataaa tactacatag aagaatactt tgagtttgac
    38881 attaatggaa tcacaatgag gggatacata gatttatatt atgtaataga tgataaaatt
    38941 tatgttatag attacaaatc gagtagtaaa ttttccaaaa aagacctacc taaaaaatca
    39001 atgcagctta tcttatatgc aatgtatctt aaagaaaaat atccagataa agtaattgaa
    39061 tatgtagctt ttgatatgtg caagtatatg aagaatgaaa aaggagtatt aattgataga
    39121 aataaggttg acagtataga tgattgtgaa agagctatag taaaaattaa atatactaaa
    39181 gaactagaga aacaattaat tgattttgtt attgatacag ttactcaaat aaaacagcta
    39241 gattccaacg atgagagtgt ttggtgcaaa aatgatgaca aaagtaatca gtttttttgt
    39301 aaaactctat gttctcatta tgaaaaaaat tgttaaggag tgataactat agaaagattg
    39361 aaaataggaa atggagaatt gatacatatg gacaatatat ccgctatgga tatatttgaa
    39421 aataattatt ttgatagctg tatctcagat ttcccatatg atttagcgtt tatgaataaa
    39481 atatgggata aatatgaaaa tttttatgaa tggaatatgt taagagctaa aaaactatta
    39541 agaataataa aaccaggagg atatgtttta atattcggtc atcatagaac caatcataga
    39601 atgaaatgtg cctttgaaga tgttggattt aaaatagttg aagaaatagt ttgggtatat
    39661 gggagtggtt ttcctaaaaa tcaagatata agtaagctat ttaataaaaa ggatttaaat
    39721 gatttagcag aaaagtggaa tggttggaaa actagcggat taaaaccagc caaggaaata
    39781 attacagtat ttcagaaacc tttagagggt tcatatatag acaatataaa aaaatataac
    39841 tgtggatgta tgaacttaga cacatgtaga atacctatat ccaaagaaga tattgatatg
    39901 ttgcagaaaa aggcgtctaa gaacccaacg aacaattatt caagccaaat aaataaaata
    39961 tatgggaaat ttaatgaaga cagagcatct caaccaaatg aattgggtag atttccaagt
    40021 aatattatat ttgataatat tatgggaaca atgcttgata agcaaagcgg aatcagaact
    40081 gctggaaaat ctaataataa tgcgttaaaa gacaaatcag gagtattaac tcctttaaag
    40141 agaggaactt tagttcccag aaatgacgta ggaggtgcta gtagattttt tttaaacata
    40201 gaagaagagt taccatttat gtattctcct aaagcaacaa aaaaggaaaa aggtgattat
    40261 tgtaaacatg ttacagttaa acctaaaaaa cttattaaat ggcttataaa attaactacc
    40321 cctcataatg gaaaaactat agatataact tctggaagtg gaactcatgg attgtgttgt
    40381 gaggagttaa acaaagagga aaaatataat cttagttggg ttaatattga acttttaaat
    40441 acaaaggaag agccttatat tgatatagca aataaaagga tttctgattt tgtaaataat
    40501 caaatttaaa taaaatttga attttaataa gattggagag tgatgagtat taaatttcaa
    40561 cctgtaataa aatggagtgg aagtaaaaga agtcaatctg aagaaatagt aaacaaattt
    40621 cctgatataa ttgacaccta ttatgaacca tttataggtg gaggaagtgt gatgtttcaa
    40681 ttattaaata gcaataaaaa agtaaaaaga tatatatgta gtgatataaa tgaggattta
    40741 atttctttat ggaacgcaat taaatcagat accgaatcat tatgcttaaa atatgaaaag
    40801 ctgtggaatg aattaaataa agatgaagat atagaaagaa agaaaaagta ttattattca
    40861 ataagaaata gttataatag tacaagaaaa ccagaattat tcttattttt aagtagaaca
    40921 tgtgtaaatg ggctaattag atataactcc aaaaatgaat ttaatacatc tcttcatttt
    40981 tctaggaatg gtataaatcc aaaaaaatta aaagaaataa tatatcaatg gtcaaaaatt
    41041 ttgaatgata agaatgttgt atttttaaaa caaagttacg aaaaggtata tcctgaaagt
    41101 aatgatttta tatatttaga cccaccatat gcaaatacaa aaggaatgta tcaaggaact
    41161 atagattatg agtatttttg ggattggatt agaactttag aatgtaaatt agcattgagt
    41221 tttgatggaa agcttggaag taaagataaa acatatgatg taccaaaaga tatatataaa
    41281 actcataatt atctttgtag tggtatgagt aattttaaaa agatgaaaca aaaacaagca
    41341 tatgtatatg aaagtttata tctaaattat tgatttagat tttaataaga ttggagagtg
    41401 tttaaatgaa tataccaaag caagtaaaag taggaggttt attctataaa atagaagaga
    41461 cagaagaacc tattctagta aataatcaat tatgttatgg attagctgat tatggaactg
    41521 aaacaataaa attatctaat aatttacaat cacaaagagt aaaagaagct acatttttac
    41581 atgagctatt tcattgtata tttagagata gatgcataga gagtgaagat gaggaatatt
    41641 tagtggatgt attagctaaa gggcttcatc aagtaattat agataatcca aaaatatttg
    41701 aatgtaaaaa aaaggtgaat tgtaatccaa tcacttatcc ttcaatcccg cctgataaac
    41761 tagaatctat agaattaaga ggaatgtaat gaataaaata tttgtatttt taggatattc
    41821 aggttcaggt aaagatagta tagtaacaga aatttcaaag caattcaata ttccaattct
    41881 aatatcacat acaacaagac ctcctcgtgg ccaatcagaa atcatcaata aaacatatca
    41941 ttttgtagat aataaatttt ttaagaaaga aaaaaataat tttattgaaa tgagaaaata
    42001 tatagttcat gatggcagca cttggctata tggtatacat aaatctgaat tagaaaataa
    42061 aaaatatgct ttgactatag tagatgcatg tggatataag gcgttagaaa aatattttat
    42121 gggaacaaaa actaagttaa taccattttt tataaataca gatgagaata tattaagaaa
    42181 aagacttatt aataggggtg ataatgctaa agaaatagag agaaggttag cagatgataa
    42241 acttaaattt aatgattttc taaataatga aagttatatt gcaataccaa acaacactaa
    42301 tctaattaat gcagtggagc aagtcaaaat acatatgaaa gaagggattg aatggtatta
    42361 gccctagata tatccatgtc ctcaactgga tgggcagtta taaatagaaa taaaaaggta
    42421 ttaaaatatg gaaaaatagt aactaaaaaa gataaattca agtctgaaga tgagagaatg
    42481 tgctatatct gtaatacaat tcaagagata attacaactc ataatattca aatagtctta
    42541 gttgaagacc aattcacttc aagaaattct aaaacaattc ttagtttaag aaaactctta
    42601 ggagcaataa tgaggactgt aaaattaaat aatatagaga ttgaatatat gtatccagtt
    42661 tctattagaa aatatctcat gaataatggt aaagctaaaa aggaagaagt agctgcatat
    42721 ataagagaaa acattattga tattggagaa tatattgata ggacttgtaa ggctaaaaca
    42781 agtgatatat atgatgctat agcacttggg atagcttatt taaacaaact taatactaat
    42841 aaataatttt aaaaagggag attaaattaa tgagtataaa tgttaaaata aagaaattaa
    42901 atcaaaatgc aatagtgcca tcttatgcaa aagaaggtga tagtggaata gatttatata
    42961 cactaaaaga tacggtgatt ccagctaaat cagcagtagc aatatctaca ggtatatcat
    43021 tagaaattcc atatggatat gaaatgcaag tcagacctag aagtggtata agcttaaaag
    43081 gaatgttttt tacaagatat gtgactatat atgataaagt gcaacctaaa aaacaaatta
    43141 gaaaaatttt tgtagcacat ccaactgtaa gattaggtac agtggattca ggatatagag
    43201 gtgaaattaa aataattaca tataatgaag aggattttga tattttaatt cctaaacata
    43261 ctaaacttgc acaaggagta tttcaacaag ttccaagagc tatattaaaa gtggtagatg
    43321 aattgactag ctctgaaaga ggtaataatg gatttggaag cactggtata agataggagg
    43381 ctatatgtat actattaaag atgtgataga tgtattgaaa tctactagaa actgcaatct
    43441 aaaatgtaat gattgtatat taaataaaag tatagttaca aataaaatag aaaaaacatt
    43501 atgttggtgg ctagaagaaa caagaaaatc tcttaagcta tcacattcaa atattgaatt
    43561 tgataaacaa attgaaatac taaaagaagt gaatgacatt atatttgaat gtgaggacaa
    43621 aacttgcaat aagtgtatat ttggcgaaga agtgagtaat ctatatagtt cttgtgatat
    43681 attagaaaag atatgtgatg aattgagcaa aaaaacatgt aaactaatag aaaaaattaa
    43741 ttattatcat gattatactt atgaaaaatt atattgttta gaaaatgtta aaactggaga
    43801 gaaatttgct gttgaagaaa atcaaataaa gagatataat atcctcaata ctaattttgg
    43861 aggtgctaat atgtttaaat atgatgatta tgttaatttg acaaatagtt tagagttacc
    43921 agaagaaatt agaaataaat gtgttagagt tgtaatgaca ttggaaaata tgcaagatat
    43981 tatgatagta cataagttca agacttatgt tgttaatgaa aaatacattg aaaaagtatc
    44041 ataaaaatga ttaagtcatc tattaattta gatgactttt ttatctgtta ataatataat
    44101 agaagtatta ttgaaaaaat aaaagaacaa attaaaatct atcacttttg aaaacttcaa
    44161 gtaattgtgg aatattaact ccgaatccct ctattaattt ttctttatta tatgaatcat
    44221 cccaactaaa aggcttgatg gtatttacaa ttttagttga ggttaatttg ttatatttag
    44281 gtttattagt tgctattgtt tcaaataata tcttagctct aaaaatttca aatctataac
    44341 cttttccagc tttttcaata tatttaatta aattatttac gctttcagta gaagtatttg
    44401 ctgttctata tccaaaatag ttaaatatct ctaagtacca actatcaact gtttttatca
    44461 cctcttggta atatttcata tttttaggaa ctgacaattt ccatttctca tatattttaa
    44521 aagcatcttc tttattttga catccataaa tatctctaaa ttgttcctta agctcatata
    44581 ctaattttaa atgtggaaat tcattgaata tcgtttgcat attctgtatt tgttcatctt
    44641 ttaattcctc tctatttttt gatagtaaaa ttttatcttt taatagtttt ttgcgttgct
    44701 taattgttaa agtatcttta aaagactttc tttctttttc tagggcattt gtaattaatt
    44761 gtaaaacatg aaatctatct ataataattt ttacctttgg taattcctca taaattgctt
    44821 ctttacaatg tttgcacata tcaattatta tgacttcgat ttgtttttta ttaggaaatt
    44881 tatttaaaaa tgctttgata tcagttttat ttctagttgc ttgaatatca agaattttat
    44941 gatggactac atctatatat atagttctta ctgagttctt aagatatagt ccatttatac
    45001 tcaacactat cggggtagtg taaactatat ttttttcaag ttccttcata taaacttcaa
    45061 acactctttt tactgtggtt ggtgaaacac tatattcatc tgcaatactg gaaaatggtt
    45121 tcttaagaga ttctttttct atctgttttc ttaatctaat agtaatttta cctctttcat
    45181 caatgctttt atatttttga ttgaatgtag aattacaatg tttacattta tatctataac
    45241 tatgtatttc tattactaca tgtttgtcaa aaatatttaa atccttaaca gaacgtgtag
    45301 actttccatg cttataatat tcagtgcaac cacattcata acatatggtg ggttcttttt
    45361 taggtttaac aattacagtc atatcgtgtt catttattat tgtatcaata acttcaaaat
    45421 ctggtaaatt taatacatcc atttttattc acattcttta attagattaa tagctgttat
    45481 cattctaata ttatatatag ttttttttgt attttgtaaa taccattcta aataacttct
    45541 attttcttta taaacatcat atgctgtttt acctttgtat tttccacttg taaaaataat
    45601 tttttttgca tcatcaagac ttatatcttt aaaataagct aataaatttt ttgatatatg
    45661 aggataaaat gtatctaata aatattttat gcaattataa cttttagttc tttctgatga
    45721 tggattgtaa tttaactgat taacaccaac acttgaaaag ttaaattctt tactgtttaa
    45781 atttcctgca taatatgcaa cacaatgctc taaatcagtt tgcattacat catatatata
    45841 ttcacctgag tattttgaga aacaaggaaa tttaacagtt ttagccttct ctagggtgtc
    45901 aacattttct tcttctaata ttttggattg tctcttttct ttaatatccc aaattaatga
    45961 atttaaatat tcaaagtcac ttaagtgctt atcagcccaa atattagctt tttcaaatcc
    46021 tatttcaaaa gattcaactt cttcttttaa aatagtctct tttaaatatt cgatatataa
    46081 gtaatatttt tcattcagtt cttttttacc attatctaaa aatttaacaa atatatcttc
    46141 tttttttact ctaaaagtaa ctctattttt agtaatctta taatgagtat cactattttt
    46201 tgtacctatt ctgtttagat aatttatacc tgctgcatcc tgtatttcaa tttcaggtac
    46261 ttttgttggt ttaaaatcaa gtttcataga tatatcaacc tcctttttat aatttattat
    46321 ataaaatatt ataccacatt taaagttata ttttccacta ttaaagttgt tttatataat
    46381 aaattccaga ttaactcttt actatctaat tatcctaata cttaattaga atttaaaact
    46441 tatcaaaacg aaatgacctt ctaaattcga ttttaaggct ttataaaaat caatgcttat
    46501 aattagtcct attcagaaat ttgattgctt aaaacgcaaa atataaaaaa taaataaatt
    46561 actagtataa gacatagaat tgtgtattct atgtcttatt tctttacaac taagtaattt
    46621 caataattat ataaataaaa gaattaaaaa agtcagttga aagtcagcta aaatgactat
    46681 tttttgcctc ctctgtatgg tataataagt atatgaattt tcataggagg gataaccatg
    46741 aacgctttta taagaaaaag aaataaaaat tatgtagtgt acttagaatt tagagatgat
    46801 gaatcaggaa aaagaaaaca aaaaaatatg ggagcatttg ataaaaaaag agatgctaat
    46861 aaaagattgg ctgaagttaa ggacagtata tataaagata gttttcttgt gccaaatgaa
    46921 atcactctag ctggattttt attagacttt cttgaaaaat ataaagataa tatttcagca
    46981 tctacatata aaagctatat tgctatttgt aaaaatcata ttaatccttc tattggaaaa
    47041 tatcgtcttc aagagttgag aaatattcat atacagaatt atatagatga tttagctggt
    47101 aacttaaacc ctcaaactat taaagtacat ataaatgtat tgagacttgc aataaagaga
    47161 gcttatagaa ttaaattaat aaaagaaaat attatagatg gaatagaaag tccaagaatt
    47221 aaaaaattta aaaatgaaat ttatgataaa gagcatatgc taaaattatt agaagtagct
    47281 aaaggaacta atcttgagct tcctattagt ttggctatag gtctaggatt gagactttca
    47341 gaagttttgg gattaacttg ggataatatt gattttgatg aaaatacaat aacagtaaat
    47401 aagataacta gtagattaga tggttctgtt atacttaaag agccaaagac agaaagctct
    47461 gttagaaaaa tatttgcacc aatagagctt atgaatttac taaaaaatta taggctggag
    47521 cagaataaga agttattgag aagtattgtt agaaatgaat ataacttact attttttgat
    47581 agaaaaggga atccaattgc tgaagatgta atgagtaaga aatttagaaa attcttagag
    47641 aataatgact tgcctcatat tagatttcat gacttaagac attcgcacgt tactttactt
    47701 ataaattcta aagtacctat aaaagttata tctgaaaggg taggacattc aaatattaat
    47761 actactctta atgtatattc tcatgtactt aaagaaatgg acaaagaagc ttctgataga
    47821 atatctgaaa acttatttaa ggctaattaa taattattat caataaatac aaaattaata
    47881 ataaaagcaa aggtataaac ataaagggga atttttacaa agccttagaa tggcatatag
    47941 agcgtcagat tttagaagat attaaaattt tatatttcca atatttatga tataataaac
    48001 atagcaagga ataaatattt gaaaaaagct gtgagtggtg tttccataga aatttcctca
    48061 ctttcttatg aaaggaggtg aaaactatgg aaaatctaat gatgagtatt atagctggtg
    48121 ttatagctag ttatatctac gataaattaa aatgccactc tgagcgacca actaagagtg
    48181 gctgggaact taatattaag ttccataaaa acaaacatta ataactaatt aatggaaaca
    48241 tcactcaaag ttaagtaaaa tatgtttcct tgcttttatt ataccacaaa ttaagaatat
    48301 taaaacaaaa ttttgtaaat acatacttaa ttatcaattt aatcatttgg aaaaaattgg
    48361 atttgattgt atgaaattat tgctgtaata tttaaattaa ataaacaaat gatgggagag
    48421 ataattatgt atttaagaaa attatcaaag tcagaattaa ttgtaatgaa atttatatgg
    48481 aatttagata caaaagtaaa atcatatcaa atcattaatt atatgaaaga aaaatatagt
    48541 tggtcagaaa aaacaacatt aaaaacttta tctaagttat caaataaaag gttcatatat
    48601 gttcaagaaa caagtcaatg tacatactat acaatttcaa ttaaagaaga taagtatcat
    48661 gaatttatat cacaaaaaat acataagctc ttagggtgca attctataaa aagcctttta
    48721 gcatcattgt ttcaagaaga attaacagat gaaaaaataa cttcattgga agaatgggta
    48781 aaaaactggg aagaagagga ataaagataa tatatactat tccttaaaaa tctatttaaa
    48841 gaataattga aattttgatt ttaatataat ttctttaatc aactctaaca tacaaaaata
    48901 agactctttt caatattaac taaagagcct tattttataa ttgattatat tttagttaac
    48961 ttttgtgtat caaaactata ctcatatact tctaatgttt cagaatttac aattagagtt
    49021 cctactgttt taatgctatc ttctttatca gtataagtat cagaaccatc agtgctagat
    49081 tcatcttgtt taacattttt aacactgatt atttcaaact catagtgtgg aaaatctata
    49141 ttttcagctt ttttatatct tgagttacca taattatatg tataacaata ttcatgtgct
    49201 tttgaacctt ttgctttata tatagcatct aaagcttttg agatgtcact tcttttagta
    49261 ttaccagtta acatataatc tggagttaag cattggtcta aaattcattt tttatatcac
    49321 ctattattat tgggaaatta gcactagtaa ctaatgattt gtcattagtt tcatttacta
    49381 aaaatacagg atattctttg tgtattgtag aagataatag tgcatctatt aaattatcag
    49441 aacttacaat acatatttga tttggatgtt ttaattcatc tttataaaaa tgcttaatta
    49501 ttttttcatt agtgtcaagt ctgtcaacac caccaattct agttgctttt gtactgttca
    49561 ctaaagagtc gtttattgat gctgttcctc caatagcata tgtttttacc ccatctgttt
    49621 taaatggtat attctttcca tttgttaata caactggatt tttatattta gcagcaactg
    49681 gagatatact tatagaatca gcctctcctt ggtaagcatt tgtaagatat atttcatcaa
    49741 ccttttttag attgcttatt tcttttgcaa cattataact tgtgtctatt ctgtcttttc
    49801 cttctatcct aataaccttt atttttttgt tttttagtat attttctaca tttttgctta
    49861 tagaattaac tccacctatt aaatagattt ttttaaattt atctaatctt ttaagagtag
    49921 aatttggtat agaattttgt ttagtaagta atattggcga gttagaagct ccagctaaac
    49981 cactagcact caacccatct gcaagacttt tatctgtgtt tataattatt gcttgggtgt
    50041 attttcttct gtctgctatt aaacctgctg tttcatactt atttgctcct tgtattctat
    50101 gagctggagg tctaaatttt agttctttag ctgaaactaa taatgtgcta gacatgacaa
    50161 tagaagatat tatagctaag gttaatgctt ttcttttgaa tttcatattg taaaatcctc
    50221 ccatcctttt atactatgaa tgatagtgta tattatttta gttgtcaact ctctatgtat
    50281 attttattat atatataaga ataaattgta ttaattatat cgttacgaaa actttttgta
    50341 tataataaaa gttcacttct ttatttattc ttataacaat cctctaaaga actaattaag
    50401 ctttctatag aattagaatg tacttcttct aaaaatctct ttgtttcaaa tattttatat
    50461 tcttcttttg taataagtat tgtataatgt gtaattcttt ttatcctctc agaatctaaa
    50521 aaacgtttaa tagtgagtct tgaaagaaga gttagtgtag ttgtcgcctt ccagttatat
    50581 tctaattcca tagcttccat aacttctttt gatgttacta tatcattctt attccatatg
    50641 aatttcataa cttttaattc agcttgtggt attttttgca tggatatgta cattcctttc
    50701 tgcaattaaa atatcaacat atatagacat taaaataata aaatatatgt tataagtata
    50761 tattaacata aagtaaaaga agatgtctca atcttaagac atcttcttta ttaaattttt
    50821 attcttcaaa ttttcgatat tcaattattt cttttatcaa tctaattatc gctttttgtt
    50881 cttttactgt taaactatca attaactcat aagcttcaga cgaaagagtt tcaacatcat
    50941 tttcattttg tataatattt tcaaataaaa cttctaaagg tatctctaat gcatttgcaa
    51001 ttttaaaaat tgaacgaagt gatgctttac tttcacctct ttcaatttga ccaatataag
    51061 caggaaacaa accagccttt tttgctaatg tattttgatt ataccctgct tttcttctat
    51121 aatttcttat tcttttacca attacattat atatttcatc ttcttctaac atttttatca
    51181 ttccttatta gattatatta gtttatttat cttaatgata tgttatacat gtcaaaaata
    51241 tacttatata acatataata ttattaaata tatgttatat aagtatgtat atatttaata
    51301 agaagctatt gtagacaaaa aaataaagcc ctttaaagaa aactcattta agagtaatcc
    51361 ttaaagggct tattatttat ctatctcttt ttcttacctt ttttacgact tttacatgcc
    51421 atgatatcac ttcttttcta ctttatatct atttataaac ctatcatatc tttagactta
    51481 gaaattttgc ctttatatct atttataaac ctatcatatc tttagactta gaaattttgc
    51541 ctttgtcttc ttttatataa atcttagttg tatcagtgga ttcgtgattg aggatagttg
    51601 atatatcttc aagtggtaaa ttattcgctt tagctatagt tgcaaaactt cttcttaatg
    51661 aatggggagc taagttatct atatctatta atttaccagc tttcttagcc caacttctta
    51721 atacattaga tgtagcctta tgatattctt tatcatattt aactaagaaa acataatcat
    51781 ttactatatc ttcttttttt ctaacttctt taagctttag taataaatct tttactttct
    51841 cactaaaata aaaatctact atttttccac ctttttcttt aatattttca catactctat
    51901 tatcaaagtc tatattatcc catcttaaat tacttgtggc tgtaactcta ccagcagttg
    51961 atagagcaaa atttatataa acctctaatt gtaaatcatc ttgttttgat aacttatctt
    52021 gtagctcttt agcctgttct atattcaaga aatgtttttc cacaacaggt aaaccctttt
    52081 taggtctttc gattagagat actggattct ctgtaacaat tctcttcctt ctaagatggt
    52141 catatagaga tgaaatgcct gaaaatatta cttttattct attaacatga ttgtcctcca
    52201 tcctaaatga aatatattcc attatatcgt cttcagtaca atcttcgatt aataaatcct
    52261 ccatttcatc atgcagatat ttagcccaag tatataagtc acatttatat acatatatag
    52321 ttttttcact taaaccagct attttcttag cttgaagaaa tcctttaatt aacttttcat
    52381 tatttttatt tatgttgcct tctatcttaa ttcttttact tcttttttca aatgttgcca
    52441 aatacttcac ttccttataa aaaagactag agaaattaat ctctagtctc taatttatct
    52501 ttaatttttg ttatgtctgt ttcaactctt tcaagtctac tgttattagt atttaatgct
    52561 tcagcaaatt tatctaattt atcatcaaac ttatctattg tattaccaaa taaagttctc
    52621 tgctctttaa tttctcttga aaaataagct ctttcctttt ttctatcatc ttgttctagt
    52681 tgtctatttt tctctaaata ttttccaagc cataacatca ataccattaa aagtatggct
    52741 gtatacccat actgacttaa taattcaacc atttctttag ataacatcta cttttccttt
    52801 ctgttctgta cttgtatttg atttattcct atagatgccc cccaacataa aataccttca
    52861 aaaacagctt ctattgacag ctctttcata aacaaacaac tacttatcat tgctataact
    52921 aacaatataa aaggtatgta tttattttta atattagatt cttttataaa tgttcctaat
    52981 atgtaaagcc cacctattaa cattattaaa ttttcaggta taaattgcat tatatccatg
    53041 tgatttcctc ctatccaaga atctcattta attcttttac tttagttttt atttgctcta
    53101 attttacatc attgttttct accttcattg aacttatctt attacatata tttattatgt
    53161 tttggccata attcatatct ggacaccatt tgcctgataa actttctact gttttagctt
    53221 ctccatgtaa atatggaaaa tgtctagggt ctaatgtagt tccatttact ttatattcaa
    53281 ctttaccaac taattcacta tattttggat atcccttagc tccagcatat aatgctagat
    53341 ggtcaataaa tgctgatact ccatcctccc aaaaattaaa tcttgtatga gctgttgggt
    53401 ctaaatctcc tccaccttta tttcctttaa gaccacacac attgcaataa gaaggattta
    53461 aaactctacc aaaattaaaa tatccagttt ctacaaatgc ttgagcaatt gcaataactg
    53521 gatttacacc ttttttctct gcttctttat atataattgg tactatagct ctgcataaaa
    53581 aatgtggtgg attagagtta ttttttaatg tgtctaaata cgaaaagact tgttctaatg
    53641 tagctgttga tttatctaat atattcaatt cattacctcc tacttgccta taaaatctaa
    53701 cactttatga agtgtagccc atctatcatc gccctgtaac ttagtgaatc tctcgctagt
    53761 tttaatttta ctggatgctc caccaatcac atataggttt tcacaatgtc caggaacata
    53821 atttttcaaa tcacacacag agacttcatt agtcttataa ttcatggcca ttaattgggc
    53881 tataacttta tctacatcac cctcataaac tattgcatat ttcactttgt tatcttgtgg
    53941 tttaccagct acagacttat taaatattcc ttcataaata tctatagcca tatctttagc
    54001 attatatttt ttagtgtcag atgtgtctac aaaacagcac tcaactaaaa ttgactttgc
    54061 cttcgttctt cttaaaaatg ctagagtttt cttttcttta actccacgat ttttaaaatc
    54121 tttatcacct tttgcatgat aagtttcagt tattttttta catattcttg atgctatttc
    54181 aacagtttct ttgtcattta aattataaac taaaacttct actcctcgac caccaccact
    54241 gttgaaatgg atacttacat ttagatcagt attatatgaa ttacatttag ctataatttt
    54301 attcaatata tcactttgag aagttccatt gttacaagta cagtcataaa ctttacattc
    54361 cttttgagct aaaggtaata actcttttag tacatttctt gcttctgtag attcctttat
    54421 atttcctatt gctccagaac ctatcttatt atctggatta tgtcctgcat gaattgttaa
    54481 tgtttttata ttcaaaatta ccactccttt taattaaaag agaattgaaa ttaatcaatc
    54541 ctctaaaatt gacataaaaa aagaaccttt atactttaga taataggttc tactagtgta
    54601 tcttctttat ttaataaatt tgttaactct gtgtattcac tttcctttat cctgttcata
    54661 gcgtaaaata catctaactt agtctgcaat tcttctctag tttcataatt cttttgttca
    54721 atcattcttt ttaaaatact atacatgttg tttcctccat tttttatagt tttataacac
    54781 gttatttgtg ttaagttcta acatagcaat tctataagca ttatctacta ataaactgtc
    54841 ttgttgcttt tgattttcta ttaaaattgt aattttatcc gcatttattt cttctatact
    54901 tggctctgat ttaggtggat tattttgtaa ttctaaccac tcattataaa cctgttctcc
    54961 tgttttaatt agctctccgt tttttatcac tggagtaaat atttttttac catctgcaat
    55021 aaagtaatta tctatattat ttaaatcatt ctcaaatcca tattctatta aaatttctat
    55081 tttcttttct atatccatct tatttttcct ttctaaatta aatagtttac atataaatac
    55141 aaccaactac gataagttat atcattataa tatatctcaa tttctccatt tgtacgaatg
    55201 attccgttat aatactttcc atctgttgtt tgaaatatta ctattatgtt tttacgaggt
    55261 gcatattttg aaggtatctt tccaatgata gtacctgccg ttgtaacacc tccattaata
    55321 gttgcattaa ttgttacaaa gttattattt gtgcaatagt ttccaacaga actagcatat
    55381 ccaagatatg gctgccaccc attaagaaag tttattgaaa atggaaaatc aattctaaca
    55441 ttgtaatttt ttatattatt tctgataact tctatatgac ttcctaaatt ttgtgtactt
    55501 tcaaaactaa tgtctggtat cacaatacct gtgttgcaaa taaatttagt ttgattatta
    55561 tattgttcta aatttagtga tgttaattca atttcttgtg gttttgaaag ttgatagata
    55621 atagttattg gattattttt tatccattca ctaaacccat ttccatcttg tgtagtaagt
    55681 ttacttttta atattttaaa tgctatatca ccactaccag tagttgagca tccctctatg
    55741 tcattattgt taaaatcatt tctacttttt ccatttaaat tattgcataa aacatatgct
    55801 atgtctaaac tatctacaac agcttgagga gttaatgttc ccataaattg cagagtatta
    55861 tcatatacat gtgataaatt aagatttcca atatcagtat aagtatgttc ctcacatctt
    55921 tttattaagt aatatttatc atttttataa actatttcat cttttattcc atttggtaaa
    55981 cttcttaatg tatatggaat tgtcttttta tcatatttat ttcctttagt tataattgtt
    56041 ttattcccat tatcatgtaa atcttttatt atagtaactc ttagatactt tgcattttta
    56101 gggcttctag caatataaaa aatatcttta tctcctatta ttctttcgtt taatgatgct
    56161 gttataaaac ttttatttat atcataccaa caaatatttc tactacaatt ataaaaagta
    56221 tactctgtat ctggttctat ttctatatag tctagggtat atttatgatt actagcttca
    56281 gaaataagtt cctctccact aagatattgt aaaatataat tatctttaaa atcggcattc
    56341 ttattaaaga tattaattcc actatattga taacttaaaa attctatttt atctctttgc
    56401 ccaacactta atagttcatt agagtaatct atattaatat ctgtataatc tccttctaat
    56461 atggtaattt tcaaacttat ttcataacca gatgtaagtg tatcgttatc taaaacactc
    56521 cttaaaacaa cattacaatc atttaagtct gatattgttg taaatgtata tttaaattta
    56581 ccaattactc ctcctggtat agctatattt gtcagattag gaataaatac tgaattttct
    56641 tcgcctaagc tatgaatata tattccactt gtactcggta aagtgttttt atcaacatca
    56701 actatgattg tatatatggt atctggttta tatgaagtgt aattgattgt aaaaaaatta
    56761 gaatatctta tatcattttc tgttagtata tttatttttc catccacaaa agttgctttc
    56821 cataaagaaa aatctgaact agtttttccc cataaatcaa ttaatgtctt tccttctaca
    56881 ttaaaattag ttaaatagcc ctttttacta ttttctatag tatattctcc tgtatcagta
    56941 ctacatttta tattgtcaac ctccttgaga ttttctatat cattgacctt tttaagtaaa
    57001 tctttatata tcaaattaaa acacctctct tcacaaaacc cctattttgt agtttctact
    57061 ctttctacta ctccactttc tttaattata caatcctcta ctgcttttct ataatcctcg
    57121 ttagttacat catctaattc aaaaggtcta ttttttaaag gattcaatcc tccatttaaa
    57181 atcctctctg ctaatattct taccacaata ttatttatat tcattataaa attcctccta
    57241 ctttttcatt ttcatttaat aaaatttgat tttctaactc ttgtattctc ttttcttctt
    57301 ctgttataaa gactggtatt tcttccaaga taggttgttt agtttctatg tttataccaa
    57361 taattctatt tttagtatag tctatacttc catactcaac atcaatacaa tgtaattcag
    57421 ttattgtatc atgttgcaat atatctcctg ttgcttctcc tgtttgcaag agtattttgc
    57481 ctgtttggtc acatataatt ctatttgctc tgttcacttt atcacctcat ttattaaata
    57541 aattttatag cttgccactt aaaagaagaa ccttgtcttt ggcaaggaag ttgtatgcct
    57601 ctattatcca tataaacatc acgttcattt aatttaagaa cttcgccttc aactttaaaa
    57661 tcttttaaat atgtttctaa gcggtgataa tgtgcagtaa ttacaaaatc ctgagtgaaa
    57721 ataccacgac aagcaaaaac aaaaaattta cgaaaataac cgctatcaat taattcaaaa
    57781 gtagtaaaaa atatattagg aacaaaatta agtccgttaa tttgaatggc tccaggaaat
    57841 aggaatagat aatcgcttcc atgataaaac ccatatttat taacacaact attaacaaca
    57901 ctactaccac tagctacttt atatttagaa tttaactgac ctatagtgtt attagcctgt
    57961 gttaatttgt ttgttaaatc ctcgatacta gcatctccac tatcaaaact tgctttaatt
    58021 ttttctgata attcaactaa tgtattattt aaacttgctt ctatattctt taatgctaaa
    58081 gtatttataa tacttgtttt cccaacttta aatcctgcat taacctcaac taattttgtt
    58141 gatatatcat ttaaatttac attttcgggc agtggcatta tattcttact tatacttaaa
    58201 actttttcag cagttgcatt attgctgtct gtaacaacta ttttaagcgt gtgcagtgca
    58261 ttatcttcta atgtatagtt aattgttttc tctgttgtta aatctgttgt tatagtttct
    58321 tttagtacat catctataaa tacttctatc ttagttaata gtgtagggtc tgtgtggtca
    58381 gctttaaatg ttgcttgtgt ggagttataa gaggatacgg ttaaaaaagg taatgcttgt
    58441 agtaatgtta ttagggcata accataagca ccagcagtat ttccaccaga ttccataaca
    58501 acattatcaa aataatattc agatgttggt gtgtagccag taggcttata actatcttta
    58561 gttaatacgt agccacttcc acctccacct gctcccacac cattcattcc tgcaccacca
    58621 aaccagccac ctccaccgcc ttcgccagtt gaatctttag cagaacaccc ttttccaaaa
    58681 cttccgtttt ctgtgcttac acgaccaata ccaccttgat attgagtacc gccgggacga
    58741 tgtctgtcgt tagcactata cccagtacct cctgctaatc ctcctcctgc accaccagta
    58801 taaggagaat atgaaccacc gccaccacct gcgacaatta tacgagatag caaaccttgc
    58861 tcattatccc aagcaccacc aacgagcctt atatcagtag caccaccacc gtacatagaa
    58921 taataagtac ccataacctg ttgatttaaa taacctttac caccgccatt aaaaccactt
    58981 ttagtgttat tactcgtaga tgaagaagca aaaccacttt cgccgacgta aacatataat
    59041 gtagtttgtt tttttaatgt aatttcacct ttagaatatc cgcctttagc atcagtatgc
    59101 caagaagaat tgttgatacc tccagaagaa ccccagcatt caaatttata tttgccaggt
    59161 ttcaatataa cactttgtgg cgaaccatta taaccaaaat tccattcagt ctgcattttc
    59221 tcactctcct ctctaacaat aagttattaa ctcatttaca ctagttgcaa tattagataa
    59281 accaccattt accttttctt ctagattaac aaatctatct tcgattttct tagacgaata
    59341 agtagtcatt tcagatactc tgttatcatc tacagttgca ttaataaaat gagtttctgc
    59401 atttccattt atcacataaa cgtttaattc tgaccttgtt tcacttctaa tttctataga
    59461 attatcatct ataattttaa aatttgtaac tacattttct tttgtagtag catctataat
    59521 atttacaact attctctgtg ttaacaaacc atgtgttaca gttgctttaa atccattttc
    59581 tgtatcatcc acccaatcat caattgttat tgtttgagta gatgccacat ttgaaccacc
    59641 tgcgataagt tggtcaattt tagtattcaa ctctgtttta gcagtttcta tatttgtatt
    59701 aactttttct atttctgtat tagtgttatt aggtacattt tttaattttt ttactacatc
    59761 ttcatttaac aatttatcac cttctttttt atttagagag ctacattagt aactctctat
    59821 tttgaacata aaaaaaagaa ctcttacagt tctatgataa tgaaatctct agtgcttcac
    59881 acatttttct tacttcttct cgatatttaa caggtacttg gtcaattgtt tttaaacctc
    59941 tctctatcaa tcctacataa attgctgcca tactacttcc tccttcattt aattttatat
    60001 tttttaatga catagtagat gtctgttgac tacttaatac catttcgcat atttcagcag
    60061 tcgctaacat taaatctgtt atgtcattat cttgcgtttt ttgacttgaa tctaaatcat
    60121 ctaattcttt tctttgtctt gacttctcaa ttttttcttt atctattttt atcatttaat
    60181 cacctcttaa agtgtttcaa catctaaatt gaataacata gatggttttt ttatagttgt
    60241 attagtgttt ccttcttcta ctattacttt aggttgtgca gattgtatat tcatatcttt
    60301 taactcatat atctccttat atccattctc agtttttctt gtctctactt taaccatatc
    60361 tttaaatgta tctgattcat ttatctttaa ttgtactttt aatttattta ctaaatgata
    60421 aattggattg ttagaattta aatcttctaa cagaccttta ttgagtgtaa gtactacatc
    60481 ttgtgaatta tcaactatac tagatacatt ataagtattc ccatcgatta atacagttga
    60541 atcttttact atagttgctc ctgtttcttt tttataaata taaacattta tatataaatt
    60601 atttccaatg tcagaatgtg ctttaaatac aatcttattt tctccaagaa ctaaattctc
    60661 tggattaatc tcaaacgtga ctgttcctgt agataagtct tctattatac ttgaactaat
    60721 attatttata aacatctcta tttttgtcaa ttcattattt ggattttgca aatctatttc
    60781 aatagatgag tatgacttat tctttatttc caaacaagtt ttctctgaat ctacttttga
    60841 gattatatat aatgtttcat cttttattaa agcatccact atatcattaa catctcttgg
    60901 aatatatatt tgtgagaaag tatataacat agaaccaatc tctacatctt taattttata
    60961 tgtttcctta tttatccctg taacatacaa agtcttatca ttttttataa caaatatatg
    61021 tttatcatca taagatttta tatattttac attttctaat actttagtaa ataatttaat
    61081 aattgtattt tttgtattct cattcagtcc taaaatccca tttatattat atccttgtac
    61141 gtataattga ccttctgtag ttatagccaa tatataatta ctataagcat atatctccct
    61201 tatattagaa atagttaata cttcttgtaa ctcattaacc tcatcattat gccctattcc
    61261 aagttgatat tctgagtttt taccaataga aaacaatgag ccatcatttt ttaagaagta
    61321 agtaaaatta tcaccacaag caatatctat tatatttgtt aagttaattt ttataaattc
    61381 agaagttgtt gttagctcag atttatttat agcaagttcc ccaaattgat ttgaaccaca
    61441 accatagaca tccccatttt ctaatatcaa aattgaatga gttgatgata aagacatctt
    61501 ttttatatta tcaaaaggca atgaagttga gtaatttcca gcatttgtgc caaatggtat
    61561 tctataatta atactatcat cattatgtaa aaatatcttc ttatttacta atagtccata
    61621 attatttctt ataatagaca tttcattaga aaaacttaaa tcactaggat tatcaccaga
    61681 agtgtttgca atctgatttt cttcatgtcc attaaaaata cctacttgac caactacagc
    61741 attacctttt ccttctaatt tattattagt atattgaact ataagaccat tatgctgtgt
    61801 atatacctgt tttacattaa ggcaatttct aacaggtgtt ttttgtacaa catcagaata
    61861 attattgatt tgacccaatt gtctactacc aaacacatat aaggcattat cattatctat
    61921 ataataagca tttttaccat ttgcatatat gtgctttata ttacttgtta atttttttaa
    61981 tactacagta ccagattcat taaaacctat accatcatca gcatttcctc cagaatataa
    62041 atctccattt tcaagtaaaa caaaaatagt gtattctcct agagcaacct cttttatatt
    62101 actattaaac gctaaatcct tatatccttc aatatatcct gatgaattat tatatgaagt
    62161 accaacacct aaacctccta atgagttata tcctgtgaca aatattctat ttttcattgt
    62221 aattatagtt ttgccttctt ccaacattaa atttgatata gttgatgggt ctgttaatcc
    62281 ttcaatattt attttagtta aactgtttga atttgtattt gaacttatgt aatttctatt
    62341 tccacaaccc attaaagaaa ttatattatc attctccaat aatataataa aaacatacct
    62401 tccacaaaat atatccttta ttgttccaga aatatttact ttagtaaaag tatttctatt
    62461 aatattatcc cctaatccta attgaccata gccatttgaa ccagttgaaa ataattcatt
    62521 gtcataggtt agaatgtaag aagatttgta acatgttatt acttttttta cattatcaat
    62581 aggcacctta gtaaaagtac ccctatcaat attatctcct aaacctaatt gccctaagtc
    62641 atttgttcca attgaataga cttgattatt atttgtaaga ataaataaac aatcattcga
    62701 tggaataaat tcttttatat tatctatagg aacttttata aattcagacc gagctttaat
    62761 tgtccctaac ttgttaccag cattattacc acagacatat ccttcgctat tatttaataa
    62821 tatatataaa gcttgtctat cacttttaat ttcttttata tttgatatga tatatttttt
    62881 agaaaattgt tttgatatat ttacaaaacc atcatgtcta acatcataag gtttttttat
    62941 gccaaaacag ccatgagaat ttactccaga acaatatatg ttcccaaaat aatctttaat
    63001 tactatcctt aatccactag catatattac ttgtgaatta tatgcaaaaa aagcatttga
    63061 taatgtgtat ttttgactat tagaataata actactgtct cctctttgcc cacctgcatt
    63121 tctacctctt atttcaaatt tagactccat ccttgtttta cttgttgtat ataaaagatt
    63181 gtctgttcca agataatgat tataataagg catagaagac gatataagac ttcttaaacc
    63241 taaattcttg tcttgggatg aagctccaaa agtcgaaggt cttcctgtga attttatttc
    63301 tttatatcct ccatcactag catctaataa taaacataaa ttatagttag aaaccagaac
    63361 ttttgataat ttaggttcat ctattaaaac tgcgacttca tttgcatttg agtttttact
    63421 tcctacaaac tctccaaacc ttgaataata atcatcagtt acagaatttt taatacttgt
    63481 gctataataa ttatgtctcc cagaaacata gtagttatta gacgtagttc taattaaaca
    63541 tccattatta aaaggaataa tttcagcaat gttagataca tctgatactg ttgtatctgt
    63601 tttatatctt gaatatctca tcttaacaaa aacgctccta cttgaggtat cattaagact
    63661 taattcgcca aaaacattat atcctgctgc ataagatatt ctgctattgt ctatgcaata
    63721 tgaagaattt gaatatgcaa taatttcatt tacataagtt acagtactta ctttagtaaa
    63781 aatatttcta ttagtagcgt cattaagtcc taactgccca taattgttta aaccagttga
    63841 aaataattca ttagtagttg tttttaataa cgcatggtta tctcctacag aaattttgtc
    63901 aacagaagaa atatttactt tagtaaaagt atttctatta atattatccc ctaatcctaa
    63961 cactccaaat acattatatc ctgttgaata taatgtatta tcacttagta atataaacgt
    64021 gaaatatgag cctagattta aatatatatc ttttatagta actccttctt ctaattccaa
    64081 tggcactcta gtaaactcat aacaatgacg attatgacct aaacctaaac ctccataagc
    64141 gttgtatcct gctgcgtata gttcattacc attcacaaca ataaatgtag aggtgtcatt
    64201 tgctttcact aaagagatat tcacaaaatt attttcaagc cctatatcta aaactctttc
    64261 atcattttta tttattaata atctattatc aatagactca atatgattac attcttcaat
    64321 atcaaagtcc tcaaattttt caaatccata tataaattta tcatatcttt ttaaataaga
    64381 aaaactataa ctgttatctc ctgtcatata caattcattg ttgctagtta atataaagct
    64441 tatagcatga gcacatttaa ttttacttat atttttaata ctaatagaag attttctagg
    64501 agtatatgtt gatctatcac aatttatttt atctcctaaa cgcccatctg ggttggctcc
    64561 agttacatat atatcattat tattagctat ataaaattta tgatatctac cactttctat
    64621 attttttaca ttagatatag atagttttgt taagactgtt actgtagctc ctccaccaac
    64681 accaacttgc ccatttgaat tatctccaca accatagaca tccccatttt ctaaaagaaa
    64741 atttacagca tcttgagcag tagaaatctt tattacatta tctaaattta ctttagtaaa
    64801 aatatttcta ttagtagtgt cattaagtcc taactgccca taggaatttg tacctgttga
    64861 atagacttca ttatttaaag ttaatatata tgaacaactg actcctgcaa atatttcttt
    64921 aacactcaaa ttatcaattt tagtaaatgt atttacagta gatgtatttc ctaagcctat
    64981 ccctccaaat ttattattac cacatacata aagctcgttg tcatttgtaa ctaacataga
    65041 atagccattc ccacaagcaa tttgttttac attacttata tttatcttag taaaagtatt
    65101 tctatcaata ttatctccca aacctaactc cccatctgtg tttaagccag tagaatacac
    65161 atctccgtta tttttaagta aaagagaatg agttccagaa gatgaaacat acttaacatt
    65221 gtcaatatct atttttgaaa aatatcttat aggtgatact ttatttccaa gtcctaaatt
    65281 gccaaaaaca ttatatcctg ctgcatataa ctttaaatca tccttaatta taaacacaga
    65341 accagaatcc atatctgtaa atatatcttt aacattaaaa gtatcaaaat ttttattaaa
    65401 ctcttctatt ttaaattctt tgtttccaaa taaagaacct ctttgtaata gtttattctt
    65461 tttcatataa ttccccctat ctcacttcgt aggaatactt gtttattttt atttcagtat
    65521 cacctttttg ataagattct tctgttttag tttcactata gttgcttcct aaatcatgaa
    65581 tatatcttat tttgttgcat aaaaaaggaa ctgttacatt tttaaataat acagttccac
    65641 tatttgaaag taactctaat tgttgcttaa atttattaag ctttaaacca tctaaattac
    65701 ttatgttttt agaatcatat agggtatcat accaataccc agcttcatct gctgtagctt
    65761 ccttatctaa ttctaattca aatagaattt taagtatttc cacagacatt ttattataat
    65821 tttcttttaa tattttcaat tgctcgtttg tatttccacc agattcaaga actttaacac
    65881 tagcatctaa ttcatttacc gcatctgata tatttttaga tactgtactt aattcactcg
    65941 aaccaacttt actttgtatt agatttattt tctctaagtt agtagctata ttacttttat
    66001 tttcatttat cttagttaga ctctcatcaa attttgcatc aattttaata ctagagtaag
    66061 tactatctag tgttgttata ttatcattta ttgtagcttg tataacttct ttatttgtat
    66121 taccatttac aacagttact tttacatcta tgttactttc attaaatatt tctatcgtat
    66181 tagaatctac tgtagtataa gaattagtca tacttttctt agttgcttca tctaatattg
    66241 ctacaaatat attttctgta actaaattat gattaactat aagtttaaaa tattctccat
    66301 cagcaaccca atccgattca acataagatt tactaaaagc tacattagtt gcagcagaag
    66361 tcatttctgc tattttctcg ttaactttct caaagtcata tgttaatcta tcctttaaag
    66421 tatcctttac agttccatca acactttctc tagcttgtat taattcgcct ctagcatcaa
    66481 gactttctaa ttcttcaaac ctattttcaa attcagttat tttattacta acagttgttg
    66541 tcatatcagt tttagcagta tttacttcaa ctattttgtc atctacttct tttatctttg
    66601 tatctaattt tgtagtactt tcatcaatac aatcttctac attagatata gcttgattta
    66661 cttcatcaag tttgtaatca atttgctctt ggttatctgt aagtttatct tcaaatgtct
    66721 tatcatacaa atcaaaagta ttattagctc tagtgtctaa gtcttgaaac ttcttgtctg
    66781 tttgagcttg aacatcaagc attttatcat caactatatt atctatttct tcagacttgg
    66841 catctatcat ttcatctaat tggagttggc aatctgtaag tttatcatca acttgaattt
    66901 gcatattctg aatggattct tcacgatttg cctcttggtt ttgacgtgtt aactcattaa
    66961 actctctttc ttcttcttgt atgtttctta tatcttcatt ataaatccta atctgctctg
    67021 ctttatctct aacttcttca tttccaagta tagttatttc aagctgttca actcttttgg
    67081 tcaactcttt attatttttt ataatctctt ctgcttgggc tattattacc aataatactc
    67141 catattcatc agttgaggtg atatcatcat cattaatcat accctcttca actctataat
    67201 aaagatttgt agtattaagt aaagttccat ctttcacaag ggatagttga aatgtattta
    67261 taccaacaga agccaatgct tgtcggctaa gttctatctc tacaacacca ttttctgcat
    67321 ctacaacttc acattcacca ttaacttttt gtccgtctga ttttgtaata ctaactaaaa
    67381 ctctatcata ttcagataaa tctattattt catctttgtt tttcaatatt gcttcaatat
    67441 aagctgtttt gacatcattt tcattataaa taaaatagtc tagtaatctt ttatttattc
    67501 tataattact aaaatctact tctatggtat gattctttat ttcataattt ttcaaagtat
    67561 cacatcctat tgttctttat tttgttcttc tagttctttt ttcaagttct caatttcttc
    67621 ttgttgttgc atgttgagtg ctttataaag tattagttca ttatataaac tttttatctc
    67681 ttcaaatgct actgtatatg ctttttgtaa atttacttcc atattaacat cctcctaaat
    67741 tattaatttt ctcgtttaat tcattaatta tcatctctaa ttcttctctt ttttgtattt
    67801 cttcttgaag tgcagttgct acaacagttg tataaccaga tgggctaaac attaatccat
    67861 tttcttctcc atagtcatat agaaatgttt ttccaacata actatcttta aaatcattag
    67921 ctataaaccc tatttgacta tctgcaattg tcctatcttt ttctgctata taatcaaatg
    67981 ttgctggttt aaaatcatct cttataaaat ctaaaaatgg tgttggagtg atacttgaac
    68041 gagttctatt cttaatatct tttatgtata ctatattctc tttaaacttt ttatcagatt
    68101 cactcagagt agaacgagca tataaatatc tccatttata acgctcacaa cctaaatcag
    68161 ttacagaacg ctctggataa aatgaatatc ctacacctaa actatctcca tttgtaaatg
    68221 taaaagtagc tccaccacat cttacaaaag tatcatctct ttcaacaata aagtgttctt
    68281 ctccatcaac ataaatctca gcagtatcat atcctaccca aaaataatta ttgctatcat
    68341 attttaatct tattgctgag gcttgactag aaccatctga ttgtcttgca tctattgcaa
    68401 atccagacct gctacttcca aataatctga ttattggttc atgtccagat ggagtagtta
    68461 atatatcaca tgctatagct ccttgattta ctgttagacc actcctgctt atctctacat
    68521 aatttgatat atcattaaat ccaaattcaa ttttatcagg tttaattcct acaattgagc
    68581 cagagttatt cctcgtaacc atcatggtta tatcatcttt agttaattta atttcagcag
    68641 catttgtttt agttgcacca tcaacttttg ctacttctaa ttttatttct ttagctgtag
    68701 catttatctg tgaaaattcc tctgatatac ttccacccat acctgttatg taaattttat
    68761 cgactgtatt tttaagttca tttatcttta agttatattg agcatttgca tttatagcta
    68821 aaattctgtc tgaaggtgta attatactat ctgaaataac tgaattaatt atagagttta
    68881 gattggtact tgctgcatcc aatgctgttt ttgaagtgtt tattgctact aagtctactc
    68941 cagtagttct atcaataagt ttttgtagct ctgtatataa acttgctttg tctgtatcta
    69001 ataaattaag ttcaatatca atcttttctt tttcttcatc tgtaacttca ttatcattaa
    69061 aataattaga catattagaa ctaaatgtac ctaaatctgc atttaactta attatagctt
    69121 tatttatgtt ttctcttaat gttatatttt cttgtgaacc accaaaattt ttagtaactt
    69181 cttttactaa tatatttaca ttttcagctc tttggtctat aagagacata ttttctttta
    69241 tatgagatgc atcttcttgt acttctaaaa ctgtttgatg tattccatct atatcttttt
    69301 caataactac aaacttttca ttatgctttt catcagtctc atataatccc caaatctgtt
    69361 cttctgtatt ttttcttgaa ttaccatcaa atgaaatatc aaaaatagaa gaatttatag
    69421 gaacttctgt gtgttttcca ttgtcattta caactactaa aaattgtgtg tttccctctg
    69481 gtaatcttac attagaaact tttaatgttc ctggattatc agcatcccag tatatatatt
    69541 ttttatttgt ctctgtatct actacttgat aaagtgtatt attgtaggta acaattactc
    69601 cagtaattct aatccatgaa tctgctggtg aattatctaa tatcaattta catcagctcc
    69661 ttttgtatat ttttcttagg aatatattca tctggtaggt taattctttt cttctgttgc
    69721 tgaatgaata aatgtctttt agagtttaat gttctcgttg catgttcagc tttagttaaa
    69781 taatcagcta tagtcctttt gtcatcttct tttatttttt tattacttaa agttaattct
    69841 aaagtatcta attttccatt ttttaaattc tgggtaaaag atgtaaaata tactaattct
    69901 tcttctttag attctttgct atgtaacact ataatatctc ccagacttaa atctcccttc
    69961 caatgctgtc taaaattaat atctataatt ctatctaaga agtttataac atccagagtc
    70021 cattctttag ttggaataca ttttaaactt aattgtctct tgccttctgc tattaaatct
    70081 tcaactttta aaaaagcatc atttgtataa gtatcataat agagaaactc atttaactca
    70141 tccaatagag cctcattaaa tattaaatat ccatcctcat cagtcgaggt ttctctctta
    70201 caaagaatat ttatatcttt tatactttca tctaactttg ctatctcttc ttctaaatgt
    70261 tttatttgaa catctaatat gaccttttta tcttctagtt cacttatttc tactgctaac
    70321 ttagctgaat ttacttcatc tttatgttct ggattatcat aagttttctt tatatccttt
    70381 ttagccttta tagtctctat tacatgtaac cattcattac ttttactatc acgttctctc
    70441 tgtttcttaa gttttgtatc tattagttct ctccaaattg gttctcttat ttcattcatt
    70501 tcctggtatt tctttatagc tctactaagt tcttcactca tttctttatt gtctaagaaa
    70561 taagaataat tctcaatgta atcatatcct gtaactgtag ctcctattat atccatatct
    70621 tcactacctt caagcttcag tctagttact atatcatcac tatttgtagt tctttcaagt
    70681 gattttatgt agttatcatg agataaatat aactgaatgt tatctccaaa actgtctata
    70741 tgatacaaat taactaaatt attataagtg tcaaaatcag ctatacactc aaattgttct
    70801 tttagttcat tattgaaata atctaaccaa ttagaattaa tactctcttg ccatcttact
    70861 ttttctctct tattaccttc actatcagtt tcataagcaa ttgaatcatc cacataacca
    70921 agtttccagc ctgtctcttg ttttaaataa tcattaagag atataataga tgcttcttca
    70981 tctttggtaa acatctgtaa tccatagtcc tcaatattca catcaatttt tcctagttta
    71041 acttctttag atttagctgt tactactttt aatttatcgt ctgtagtcac aacattctta
    71101 actacaaaat attctttatt attaagacaa ataagacgtt cttcttttac ttcttcaaaa
    71161 atgggattta ttattttatt aaataaaaat ctatctgtaa tatattttgg aatggtcagt
    71221 tgtatttcat ctactccacc aagctcacgc tttatagaat ttaaaaagtt gattgggatt
    71281 tgacctaaaa atgatttgtt catcttgtga atggttaatg tgtaatcaga ttttatctgt
    71341 ttaagattca cattaaaatg catattttat caccttcttt gtattagaaa agcccatcaa
    71401 ttaagatgag ctaaaatatt ttattaatct aaatattgca acaagtttaa tagcttgtta
    71461 catatatgat aaagcaaaaa acactcaaac gccaataaga gtggtttcaa aagataaatt
    71521 gattttttaa ttaactttaa ggaaacaatc actctttgta ttaagtagat taaattcctt
    71581 acttttatta tatcataaat acgttttttg taaaacagat tcaataaata aaaaatcact
    71641 attactgata tcaattaata catgttttaa ataggtatat tataaatcat ttcattattc
    71701 aaaattcact tcaatatctt caaggtcttt ttcattaata tttaggtctt tcagaatttc
    71761 gttttgagat attagttctt tttcatctat acctttcatt cttatttctg tctcaataag
    71821 aagcttacaa tcttctatat tatttatcat ttgtaacacc tccttaaata gataccagag
    71881 tatgaaaaaa gccacttgtt taaggtggca tagataagta gtaattcttg tgtaaaattt
    71941 ttaaattttc tgttacctgt attatatctt tattctactc ctgtcgtcaa tataatatta
    72001 aatttaacat tatggaaaaa tatggtataa tatttttaga gactacagtt tagactatta
    72061 gggtgatggc tctttagtta aaatccccag taagaaaggg ggtgagacta tggagtactt
    72121 agttttgttt ttaataatga taattatgat tacaagaata atcaatcatt tgacaaagct
    72181 aatagatgca atcttaaact tgaaagcatc tattaggaaa ctaaagaatc accagactgg
    72241 cgggtctagt gattctgaaa gtaatacata aatctattct ttttattgtt aactttaaga
    72301 actacaccct acagcaaata gtttgtagtc tcttttttat gtccctatga tataaattta
    72361 tatcatttat attactatta tactccaata ttatcaaaat agtcaatgtt gtcattatct
    72421 tcattgaaaa ataaaaaagc tatattatta atagaataac ttcttagaac acaatattct
    72481 tttacaattg tagacaatat aatattaaat ttaacatatt ggtaatttat ggtataatat
    72541 ttttagagac tacataaaaa aaactattag ggtgaatctt catatacata agccttccca
    72601 tgtcaaatca agaggggagg tgatatgata ttatgaaata tctaatttgt ttgttaacga
    72661 taataacatt tcttacaact ataattatta gtttgattaa gttggttcag aatttaaata
    72721 gactctttaa agaaatagat gagtttaaga aaacgttgca aaaaattaag aatcacccga
    72781 acggcaattc aggtgattct tcctctaatt aacacttcgc ttatttatga agagacatcc
    72841 tagcacaaat agttgtagtc tctttttttt atgtctttat gatataaatt tatatcattt
    72901 atattactat tataccatat acatattatt ttttgaaata aaatctggat tttattagag
    72961 aaatctggat ttctacttaa aatcctttgt ttatataaat aatctatgat ttaatatttt
    73021 ctactatttt tctatatact ctattttcta aatctctacc aaatttctct aagtctttca
    73081 tagtatcctt agttacattt ccttgaacaa caaagaatgg tgaattaaag ttgactgatg
    73141 atgttggaga cacacttctt gaacgagaat ttgaagaagg attataatta ggcatagcaa
    73201 atttacttaa atctaattca tctaatatgt cgttaatatc ttctaatgtc tctttacctt
    73261 cttttagctt atcgagccat tcctgcttag tgacagaacc cattgccaac ataccatttt
    73321 catatttatt tatgtattca ataatagcat cttgaagttt cttaacttct ccatcaagac
    73381 ctacaaactt accgcttgaa attgcttcat taattaaatc aactaaattt tcatctgagt
    73441 attttttctc taactcttct tttaatttat ctgcttcttc ttgtagtctg tcagactcct
    73501 tatcatacat atcattgact tggtcgtcca catggtcttg tactaaatcc tgtaatttct
    73561 tctgttcttc ttttaattgt ttttgtaaat ctttaagttt cttctgacca cttaaagaac
    73621 tatctctttc agctattgct atttgtttct ctaaatcact tattacatct tgttgttctt
    73681 cataatcatc tttatatttg gcttcttttc ttgaatcatt gtaagcatct tgttgctttt
    73741 taagagaatc aattttagct ttagtttctt tatctatttc tttaagtctc tcttcaagct
    73801 cttttttata catgtctcta attttttctt gtaggctttg agcttcttta agctggtctt
    73861 tataagcatc ttgaatctct ttatttaaat cttctatttc ttctttattt tgttgaattt
    73921 gtttattagc atcaggtaaa tctttaagaa gtaaatctaa atatttctta gcattttctg
    73981 ctatttcttt gtatttatct gcatctttat tattttttag aaacgctaat tgttgctcat
    74041 aatttgttat gcttttacca tcagcagaaa atttaaaccc ttcttttgat aacccttctc
    74101 ttaactcttt tgcagtatct tcataaactt taataacatc tttaatttcc ttagcttgtt
    74161 tggccaataa ctctttcttc ttttcaatta agtctaactt ttcatcacct tcagcatttt
    74221 tcataagaat gtctattaag tctatttcgt tttgtatttc agtaacatgt ttttgagctg
    74281 aagttaaagc agcttctcta gcaatctctt ttaattcttt tttaaattcc tctgctgctc
    74341 tagttgattc tataagagaa tttgttactt cttgttgagc atctgcaact ttcggtatct
    74401 cagtaaaagc aatctttaaa tattcttcaa caaccttttt ctcttcttct attttcttct
    74461 tacgttcttc actcttttta ctacctttgt cgctctctga ttgcttatct aatttctcta
    74521 attctttttc taatgatatt aatttttctt cataactagt taagttatca tcatctgaaa
    74581 aagtgtactt ataatctttt ttaagtctat cttttagtct attcttttga gtgttaagtg
    74641 ccttatcttt ttggtctaac aatgttagtt cttctttata taaagcgttt tgttcttcaa
    74701 gatatttaag tttatctttt ccacttgcat atttcatttt cttatctaaa agagatattc
    74761 tatctgacat ataaactcta taaattaata taaatacttt ataattttta tagttttatt
    74821 tcctttctca tcctgcccta ttttgaaatt cataagaata tctactctag tttatataac
    74881 agtccaaagg cttaaattcg acctcgtcaa tgtctacata ttagcataat ctttttattt
    74941 gattttctat gctaatttaa gtaatcatgt tggtgattac ttttataatt tgctaaatta
    75001 atacttgcat ttttatccct atcaattaca agattgcact ttggattaga acatatataa
    75061 gtcctatctt ttagccttaa atcctttttg atagttccac aacaagaaca aattttacta
    75121 cttggataaa atctatctgc tttaacaaat tcgattccat tccatttaca tttatattca
    75181 agtatagcta taaatttatt aaaacattgt tctgaaattg ctttagataa gtgtttattt
    75241 ttcatcattc cttttacatt taaatcttca actactaccc tacaaggctt ggttttcact
    75301 attgtattag tagtttgatg tatgtgattt aatctaatat ctgcaatttt tttatgaaca
    75361 atttttatct gtttttcaat ttttatgata ttttgagttt tagaaaactt ttcacccttt
    75421 ttgaatgtat taccactttt caacatatca tattttcttg aaacttgttt ttgaagtctt
    75481 ttaagtttct tatttaatct ctttacttct tttgatttat tgatattttt aaaaggattg
    75541 tctatattgc taactattgc taaatcttta atacctaaat caactccgat actttcatct
    75601 ttaaggtcag tgtaagcttt atcttcgact tctaaagcca aagataggta ccagaacctt
    75661 ccattaaact ttattcttgg atttaaaact tttattttat cctttttata attaccaatc
    75721 ggaagtctgc cctcatcttt cattttcaca taacctattt tctcaagttt gatatattta
    75781 tcttttacaa taaacttatt gtttaaatga aaaaatgaaa cttcacattt accctttttc
    75841 ttaaacctag gaaaacttga ttcttttcta aagaatttct taaatgactc tcctaaatct
    75901 ttaagtgctt gttgtggtat ttctgatgat acttctttta accaactaaa ttcttcatca
    75961 tttcttatat ttgtaaattc ttttcttaat tcacctattg ataaagtctt attgttttct
    76021 tcataatatt tattaagaaa agctaacccc cagttataag aaaatcttgc aataccagca
    76081 cttttaaaca ttaactcttc ttgtcttttg gtaggatata atctaacttt aattgcttta
    76141 atcattatca attaactcct taatcatatc tttagttttc ttagctcttt taccttgaag
    76201 cctacaactg aaaacagtaa ttatttgtat caaatcttct acaatttctt gttcttctga
    76261 tttttcagta ttatctataa cttctaaatc tactgattta aactcacata tattttctat
    76321 aagttcaaat ccaaatctaa caagtctatc tttatataat aaaacaactt tagaaacttc
    76381 atcttgtaaa atcatttgaa ttaattgatt gagacctttt ttatcataat ttataccact
    76441 acctatatca gttattattt taaattggta tccttttgaa attaaataag ttcttacatt
    76501 ttcaacttgt ctttcaagtg cttctttttg ctttgcactt gaaactctac aataacctac
    76561 aactattctt tctttattag taacctctcc ataaaattct ttaacttgct tttctgtgta
    76621 gtatctatag ccagtttttt catctacaat ttcaggtttt aattttccac ttttatccca
    76681 atttcggaga gtttgttgtg tcttattaat ttttttagca aattgaccta tcgagtatct
    76741 tttcatcaag accacctcct aaaaatatat taatatattt ttagaaaaaa gtatatcatt
    76801 tttataaagt atttatatta acttatagag ttttatactt tttaccatac aacgctactt
    76861 gtatgatgct atttcactca cgctaatagc cacttccttt cggaacgtgc aaagactatt
    76921 tcttcatctt cagcattacc tgttaagagc cacccatttc ttccctcaat cgcttagggc
    76981 tttacgacct ctcggtctag tcgtttgacc ttcctatttc taggcttggc gaccaaatct
    77041 ccattgtata agcacttagg atttaaccat atgccatctc tacacttgtt atgatttctc
    77101 cccatcataa aggtttctga ttctatcctt tattgtggta gtagagcttt agggtttact
    77161 ggttttaaag tggtgtccta tgcagatttc tctacatacg cagtatagtt tatattttta
    77221 taagaagatt ataaaatttt ataaactatt tgttactgta actttagata tcgcattttc
    77281 taattctttt agtaactcaa tgctatattt tactgctgca tcaatagatt ttgtatctaa
    77341 tgctatttta ggagttttag ttatacgaga gaatttctcc gtaagagttt tgactggaga
    77401 tgtggctctt gatactgctc ttgagaatag agatggtttt gttacaggag tttcgtcact
    77461 tattggtact ggttctgacg ttctaggttg ggctgataga ttagctggaa ttgcttgtgt
    77521 agtttctata gaatttatgg attgcacact ttttctatta ctctttaatc cacctaatat
    77581 attatttgca aattgagaag caattcctcc tagagtccct actgtacgaa gatgtgctgt
    77641 tattgtaaaa ctcttatcac ttagtttttt attttcagtt tgacgaattg tttctaaagc
    77701 agcagaatta ttcgctttaa gtttagccca cttgtctttt attgtttttt tatcaacact
    77761 atctatgccc tcaatagctc cttcaatagc tgcaattacc tcaacttgtt tttcaggagg
    77821 taatttttct atttcagcaa ttaatgaatt aatatctcca ttagttagtg attttattat
    77881 atttattttt acgtctttgt ctaggtctaa agcatttaaa ttctcaactt catctaatgc
    77941 atctggatta tttactataa gattagctat aatgtctttg ctttcaggga aatcattata
    78001 aagttgttct attaaatata acttatcttc attatttaac ataaaattaa gaacttgatt
    78061 tttttgttca tctggtgttg attcatatag ttttgtagct ctctcaagct catctgcatt
    78121 ttctacagca aagctaacaa ccttactttt tgtttcttct ggaacattat catatagttt
    78181 ttgaaatgct tcagcctttt ctggattttt aattataact tcggcaaata cttttttatc
    78241 ttttttgtct tctaatccat catatataga tttcatttta tcaaaatcat ctaaaccatt
    78301 taaatttatg ctataatcca tagctatagt tggattatcc ataagccatt tttgtacggc
    78361 ttcatagtcc tttagatttt ttaaactatc aacattatca gttataaatt tattagtaaa
    78421 agttgaattt gttggaagat tttttactat atcagcaaaa attttaactt gttcagtctc
    78481 aatacctgat gattctaatt ttaattttac atcatttctt ccttcaagtt gtttaaatga
    78541 atttaaagta tttctaagct cttcattttt ctttaactta agttcaattt gttttgttgg
    78601 aggtgtattt aatatatcat ctacaagctt ttctgcttct ttatcccttg aaaatgcaac
    78661 acttttagga ttcggtttgt cttttaaaac ctttttagta gattctttag cttctttaac
    78721 agggtctttc ttatctttat caccatttat ttcttttaat tttttttgaa tccattcaat
    78781 agcacctgat gctaagtctt taacctctat agtaaaaatt ttatttgcta tttcagaaga
    78841 actaatagtc tcaatatcat ctttagcttt ttctatttcg gcaattattt ctactcgttt
    78901 atctggtggt aaactttcaa tagctttgcc taaagcatct atatctccat cagataaggc
    78961 tttgtatata tttattctta catccttatc taaaggaatt ttatccaatg atgttattaa
    79021 atcctgaacc cctaatttac catcattttg cttcaaatat atttctgtaa ttttctcatc
    79081 aggtatatgt tctaaagcat cttttaaatt aacagaatta tacaaagcct ctcccgcttc
    79141 tgctataaaa tatgttttaa gttccgcagg tactttctta tatatctctg atacttcaac
    79201 agctttttct agtccaactc catcagcttc taatttagtt ttgagttcag aaggtacttc
    79261 ggcatactta gatgttaaat ctaatatttt tctaccacct tcgtctgctc cttcttcttt
    79321 tatgatagtt tttacttctt ttggaaattt atcataaatt ctttttactg aatcagcttc
    79381 ttctaatgtt gcagttggat tagcttttat gactgtgatt acttcttctg gaagctcctc
    79441 atatctttgc tttaaactac ttattatttg ttctgcatta gcttgacctg aatcattact
    79501 taaaagtatt tctggagtta tagtaaactt accttttcca aatttattat ctaaatcatt
    79561 ttgaagttta gttatatctg ggtcaccagt ctgtaattcc attaatacat ccatagtgaa
    79621 ttttaataca tcagtagaac ttgcccctgt tcctaataaa gcatctatca tgcctttaac
    79681 ttgactagga acttctttag tattcttaat gtcagttaat atatttgcat caacttttac
    79741 atctccagtt attgttgttg tatctaatat attctgaata ctatcaaatt gattttggag
    79801 ttgcatcgca agtttatcac catttgctaa atctagtttt gttttaccaa acttagctag
    79861 taatgtattt atagatgtca tatctttaat tccatttgga tttacttgcc caaataaatt
    79921 ttcccatata ttagcatctg tgttagttgc tttagctata ctcttagctg ttttatctat
    79981 tgtttgatta tatttttcta tatcttgtgt tctagcaaat tcttcatttg catccttaag
    80041 agttttagat aaatctccta catcaacttt cccacttcta acagcagtaa gcaatttgtt
    80101 gactgcctgt tctgtgtcta ctagagtatc tggtgtaact tcactaaaat caaataaact
    80161 ttcaagtcca gcaaaattag acttatcatt gccttctaat ccactataaa gcgttttatt
    80221 cttaatgtta gaaaatattc catctcctat ttcttttgaa tacccttgaa ttttatctac
    80281 ttgatttcta tacatttcat catatttgaa atatattttt tcttcttctg ctttagctga
    80341 cattaattca tttctagctt tgtctcttgc tctaccagtt gaattgttat atttctcgat
    80401 tgctttttct tgtctttttt tattcttttc aacttctgct gtataatctt cttctatttt
    80461 tacaagctta ccagtttcac tttctctcat tctttcttct aaagttttat ttacatcttt
    80521 acttggagaa tttaattttt tagcagcagt tttcgcatta tcatgtttat cataggacat
    80581 caatctttct tttgcattga tagctctatc tatttcagca attaaatcag taacctgacc
    80641 ttttaaaata ggtataccat tttcatctgt tcctataact gtatctggtt ttatttttgc
    80701 aatctgttgt tttagttcat ttaatctatt attatcttct ttagacttat tttctttttt
    80761 agataaatta tcatattctt ctgcaagtgc ttgtaattga actttttggc tttcatatga
    80821 attaatttgt tgttttgaag cttgaacatt tttctttcta gcttgatatg cattttcttc
    80881 tctattggca tagttttcca tagcttgagt caatagactt attcctgcaa aggcagcagt
    80941 taatactaaa gaatttccaa cagtagaggc aatacctttg ccaaagtttg caagtccact
    81001 attcattaat aaattgcttt tttttgcctg tctagttgcc ttttcaactt ttccagaaga
    81061 ggctaacaac ttttcattag agctaattat agctttatta gaacctgata tttctctatt
    81121 tttttgtact aaatctttat atgattttga aattttacca ttagccaaag ctgtttgatt
    81181 cgagcttatt cctaattcct tataatgttt agataactta gctgtttcta aggatgtatt
    81241 ttttaaatta ggaacgcctt ttttaatagc tttattcatt gctgtggcag aaagtgcata
    81301 tcctttagat gcaattgtta catcttttaa tctcccatct tttccaacta taacttcttt
    81361 aaactctttt atatttttct gaaagtcttt actaaatgaa cgtgtaggat atttaaaaga
    81421 ttcttttaat ccacctaata aattagggac agatttacca gtacctaatg ctttaattgt
    81481 cataaacaaa gatgataaag tacctattgc taatgggagt gaaatatgca ttttgtcagc
    81541 cgctttagtt ataccattta aaattccagt aataccagat aatccatcta aactagtctt
    81601 aaacatatct gtagatatag tatctgtaac taattgttta agactttctt ttaattttat
    81661 aatcttaccc tctgctgaat ttatgaatct ctcattctct ttttcagcag agccaaaaac
    81721 ttccccattc aaaaaatcat tttgaaattt ctttgtttga gaccaattat ccattattgc
    81781 aaaaaaggta ttgatatggt ttttgcctga aatcgcttca gcaataccac ttttttgatt
    81841 tttagttaaa gcatcttccc caacactatg ccacttttct gccaactcat ctaaaattga
    81901 catcatatct cttacttggc cagtttgctt atctaacaca tttatttttg ctgtttcttg
    81961 taaagttttt gctgttttat tgagtgaaat ttctcctgta gaggcagaag ccttgatacc
    82021 actcatgttt atctttaata ccctctgttt ccagatattt aaaaatggga atagactata
    82081 ccattatctt tcataagata ctcattgata gtcgttgcga cctttcctta tcaattgact
    82141 taggactgtg tctcaggatt atccaatctt taatcttatt accataccat tgtgattagc
    82201 aatgccacat tttgatttct ctaatgcttg gtaattaaag ctttaaggac tttccctgat
    82261 attctgagtt caattatata tcgctatata aaggggctat tttgttaacc aattgttttg
    82321 agtgctgtac ctactttttc caatttgtta tcctacaggc tttttatcct atagttctta
    82381 tacttcttct ttatataagt tcagcatata ttttcatctt cagcactatc tgttaagatg
    82441 gaggacactc gtgggaaaat tatattctat actattttaa acataaaaat agcataggtt
    82501 catttcctat gcgttacggt gattaaaatc ttttaattct ttaatttacc tcggtggtag
    82561 catctcagcc ttcaccgatt ttgccccctc ataatattaa ttatttctaa ttaacacgcc
    82621 aaaagtttag cattttgtac agattcattt cctccaatta tcaaagcaac agagtcttcc
    82681 attgaaacac ctgctgatga taacatactt gcacttcttt gtaatgcagc tcctacatcg
    82741 ccagttgtta ttgcaaaatt attacctgca tagttcgata aatcaagaaa ttttgtaaga
    82801 ttatcataat ctttactcat tcctttgatt tgaactctag tatctttaat tggttttaat
    82861 gcttttgtca ttccaccata agcggacata acactagtta agtacttatc agcagtttct
    82921 tggtctaaat caccaacatt tgcaaaaact gctgattgtt tagctatctt caaactgtct
    82981 gataccgatt ttacaccagt ttgtagagct ttagatgccc cctgaattat atcttctgat
    83041 gctctagccg tatctttccc tattgagatt gcttcatttt ttacattctt taattgctca
    83101 cttgttcctt caaaattatt aggtgctact ttcatcatat ctcttaaagc actatctaat
    83161 tcaacaatag ttgttttaat atttcttaca ccatttgtaa tagacatacc tatcatatta
    83221 cctaaagtat aagttctcat cgaattatat aggtcactaa aaaatccact tgttgctttt
    83281 acactagttc ctaatcctgt gaaattagat ttcatattgc ttaatctact ttttattgaa
    83341 tctaattcct ttactttttg acctagaggc ataccattta attgcattaa ttctttttct
    83401 agtttatcaa ttccagcagt tgattgaccc aattctaaac atttttgtct aagcctattt
    83461 aaatctgaaa ttactttgga aagattcata ttaaacttag catctaattt agtattttta
    83521 gtagcatttt ctacttcttt aactttattt tttaattgtt ctagtttttg tatttctgat
    83581 tgtatttgat tagaagttag atttttaaga ttcaaatttt gaattgactt taatgaattt
    83641 gataaagctt gtagtttaga tgtatctgca tatccagact tacccaatgt ttctatttta
    83701 ttagctaatt ttccagcttc attttgaaga gttttaaatt gagaagccat ttttgtattc
    83761 atatctggta ttttcatatt agccaactta gactgaacat ttgataaatc tgatagagcc
    83821 tttgaattta gaccacctaa tttaatatta gataatcttt tcaattctcc tgataatttg
    83881 ttaatttctc ctatttgctt attgtctaaa atatttgtct gagtaaattt ctttaattgt
    83941 ctttgagtag actctatttt ttttctaaag ttatcgtatt gagaagttaa tttatttata
    84001 ttcccatttg aattaccttt tccgccaaat aatccatttt gggtttctct actaagttta
    84061 ttaatttgtt ttaacgtgtt ctctaattgc tttaaattat ttaatgagga tgtattcatc
    84121 tccacattta actttatatt attttctttt gcagatgtct tcagtgatgc taattgtttc
    84181 ctagcttttt tatcatcaag ttctatactg gtcttaattt taaattcttc tgccattcaa
    84241 ccaactcctt ttttaaagca taaaaaaaga cagttaatat actgtcttaa tatttttatt
    84301 taattttctc taataatact tttttctttt cattaaattc ttcttctgtt aatatctctt
    84361 ggtctttcaa actctgtaat tcttttaatg aatttgaaat ttttgatata tcatcatcat
    84421 ctttttttat atcactgtta ttttctgact tagcattttt aaatttttca acttcattct
    84481 ctacaaccaa tttaaatctc tccatttcat ctatatcata ttggattatt ggattagtaa
    84541 tatttttata ttcagggata atgaaaattt cttcagtgct atttgcaaat ataaatttta
    84601 acgatatttt ttccaccatt gtatgtttgt catatgtagg caaaatggaa ataactttca
    84661 taacattttt ttctcttatc tgtatatcaa gcttaatctg taataaatca tctaattttt
    84721 taatgagtac actgctacga tttcttgctt taaataccaa tctattatct gatgttaata
    84781 ttatatctct acttccttca tttccctcaa aagcatcttt tgacaaatct actgcttttg
    84841 atataatttg tctcgttgtt agtggagcat ctttaggtct atttctctct tcttcaactt
    84901 cagccctaat tcttgctgtt cgtttttcct cttcttcctt tttttctttt tcttttacac
    84961 acttgaaaat aaaattaaag aaaataaata taactatacc aattattaaa attaaaaaaa
    85021 atgaatattc actatcaaac ataatatccc cccctattct gatacattaa ttatatcaag
    85081 tctaaaggaa aatttatact aaaaaaggaa atagaagcca aaacttctat ttccataaca
    85141 tcatttcaaa tatttattaa tatcttcttt actagcttct tctatgtaat ctatcataca
    85201 gattggaatg tctctactcc tagaaatatc tccgatttct tctactctta ttttctcatt
    85261 tcttacactc tttaatattc caataaatcc atagtactca tggtcatata tagcatatgt
    85321 tttgcctatc tcaaccatta caccttttat gtaatcatta tttatcataa atctcttaag
    85381 tacctgacta ttctctttca atattttatt aagaaaatat atttgtcctt ttccagttac
    85441 aataggagtg tatctaacta tcgtattccc atctttatct acaccagtac tctcagaaac
    85501 ctctaatact tttaaatcca ttgacttttg agttggtgta ttatggtcag ctcttttctt
    85561 cctaattaaa tattcattgt ttctcatcca ctcaaataat ctattctgtc ctatatctac
    85621 accattctga tttaatatct tagatagttg agcaattagt attgagcttg atgaactttc
    85681 tatagcatta gctagttcaa gtttaggttt atttttctct tgctctactc ttaatttttc
    85741 tttagtagct ctctctttct ttagctctgt gagtagttgt attgtccaat ctgggtcatt
    85801 gattgccttc tctagtgctt cattagtcat ataagctcca tgtttcctta ttgtgggtaa
    85861 tacttcattt gtcacccatt ttttgaatgg tctacatttt gctgttttag cttctagcat
    85921 aaaatcgtat agttgaggct cagttaaata ttttgtacca ctgcggtcca atggcttaat
    85981 ttcagccttt tcaataacat tatcaattct atctcttctt atttgaagat atctcttacc
    86041 accacttgga ttatttctag tataaccaag tgcagctcca gtagaatata attcaaacaa
    86101 taactctcca tttaattcaa ttatttctac atccatacct tcaaacttct tacttaattc
    86161 agattcctca aaactcatta tttcgtttac attttctcta ttaattattc ccataattaa
    86221 tacctcctta taagttgtat tttttataag gaatggtata taatatcatt agggtgaatt
    86281 atataccata aggggttatt caaacttggt cgggcgaata accccttttc ttatccttat
    86341 ttttctagct catcataaac ttttttgata cccaatctaa ctacatctgc cttagtaagt
    86401 tttaactctt tacagcaatg attaagtatc tcaagttcat catctgacat cctaattcta
    86461 tattcatttt ttttaggatt atcagatgga ggtctccctg ttcttggtgt cattccaaac
    86521 ctcctgactt attggtgata catttattat attattggtg acacaaaaag tcaatatgct
    86581 atttaatttt ttgtaatatg ctcaatatca ccttaattta attatatatc ataaggggct
    86641 attcaaactt gataggggag aatagcccct tttcctatcc ttatttattt ttataacgtt
    86701 tagtatttta taatacttat tgttatattt atattatatt gccaacattt tgttatgtca
    86761 agtatatatt ttataacttt ttgtgttata atatatgtat aggaggtctt agaacatgat
    86821 tggagaaaaa ttaaaacaac ttagaattaa aaataactta aagcaatccg atttggcaag
    86881 aatattagat gtaacacaag gagctgtagg tatgtatgaa aatgataaaa gaactccatc
    86941 tccagaattg atagttaaac tagctgaata ctttaatgtc actacagatt atcttttagg
    87001 tcatacaaaa accaactatt cagtcagtgc aaatatacct ggtatgccat caatcgtatg
    87061 tgaagataat tccatctatg atatacttga tgggaaaaaa gacattaaat ctttaaaaga
    87121 tatgaataaa ttcttagaaa atactgatta caataatgaa gtcaaagaag ttcttaaaaa
    87181 atatatgcaa ctagatgaaa tggatagaaa agctatagag agaatgatag ataatgcata
    87241 tgaacgacta aaagaggata attaatatac acctcttttt tttataccat attagcccaa
    87301 tgttggaatt ttaacatgcg tccacagtgg atgccattta ttatatttct attctccttt
    87361 agtgaagaat tattatatca acaggagtta ttaatttggt atatcctcaa tcctatcaca
    87421 ctcaaagtag tgaccactca aacatcaaaa taagctctta tggtggctaa acaccaaaca
    87481 aaatgttcct ctcaggaaca cttgttgaaa ttccaatact ttcaaccata aaaatcaacc
    87541 tcttatgttc gattctaagc aattaaggta taaacacaag cagtcatttt tacaaaacct
    87601 tagagagtcc tacacgaagt tataatgttt aaaagtcttt catttctttc tatttccttt
    87661 tgacttggtt tactgaatac ttgccttata aataattcag cgtctttacc tgataattca
    87721 ggtgttgcct gaattggttt tattttatgt tgactcatat tgtcacctcc ataattaata
    87781 aaagaaaatt atacttctca aagtcgccaa tagcaacgac tatttattac ttttaataat
    87841 atctagtatt atatgtcttt caatatttcc aagtgtctta tacttgtcat acacatgtca
    87901 tcattgaaat aactacaaca taaatgattc aataaaaaaa acaatccaaa ttgattatct
    87961 ttaatattta ttaatacatc ttgatattta ttctatctcc acacctttaa ggtgtactat
    88021 ggccactcgc cttatctata ttaatataat aataaacgtc ttataaattt tacaatttaa
    88081 tctctaaaac ctatcttata acttatacat tcatcatcta caaaataaat tatatcattg
    88141 aacataaaga agctataatc atttttcttt gcctgattag ccatttttat tatgtctcca
    88201 gtccaaatat catcatcata attatatatt aaatattttg gaatattgac tttattattt
    88261 gtaaaactat ctttttttaa ttcttacttt tctattatct taccacaaga ttccctaaaa
    88321 tgtatattag gataatctaa ttttcttgta acctctaata cttcctcgat gtattcaaat
    88381 ttaaatgtta attaaaacaa ttatacctct ctccttatat caatatgtta tatacaagta
    88441 tatttcacaa tatacttgta tatgtttttg catcaatcaa tgtattagaa cattgagaaa
    88501 caattctaaa ccgcttatct aagcaaatca actaaactac ctatctaggt taaattgctc
    88561 actatatgtt agagcatcac cgctttttaa ttttccactt atgatataca tctactagtg
    88621 gataacatac aacccttaga aaactctata acttaataga cactcgatat tatctatttt
    88681 actggtacgc ctaattcatt cattttagac ttaaaacact taggtactct ctcttgtgct
    88741 ttagaattac tctcttccat tatatttgtt tgaggtctat atccgccaac accccagact
    88801 ttcccctttt ctaatctttc cattggaaat gctgaattac gtgtaaatgc atccacccaa
    88861 tttccattat tttgtatctc tgaagtgaca gaattagaag agagttctgt aacatctata
    88921 gcatctaata attgtcctgt tctacctccc caaacattag gattccattc tccaactgga
    88981 gtataaccag aataaacctg tttatttact tcttccttca taatttcttt catttctttt
    89041 ccaacttctg gcatagatgc agcaatctta ttttttgtat aagcaactag ctcatccaat
    89101 gatttaaata ccatctaatt caccaccttg tctttaatat tattcatttt ttcaatttct
    89161 tcagtttctt caatttcttt taaaaccctg tcttgtaata tctcattctt catctgacct
    89221 aatttaacat cagtgttcat taataaagat gcagttaatt catttcctat ttgacatatg
    89281 tgatacatca cagtttctaa ttcgctagat atattgctat ctactaaatc ttctatttca
    89341 atatttaact ctatattagt caatttatca atcaacattt taagaatatc ttcttgagac
    89401 aatgctaaat caggattctc cataccaacc catattttat ttaatatctc ttctttagtc
    89461 tccttatcag gatttctaac ttctatatat tcctctttac cattctcatc tataattggt
    89521 attatagccc taacttcatc ttgtattaat ttatctactt gtatttttcc catatctatc
    89581 tctcctttat tttattattg gatatttaca tttaatagaa actttacagt ttccagtaaa
    89641 cttcaatata tttacacctc ttcttaacct aatccacttt ctattaacaa tattaaacct
    89701 attctcacca gtactattca aaacagtgta atacaaatta tctattgtta ttttttcatt
    89761 taattctaat ccacttataa ctaaactatc ttcttcatta tcgctgatag tggagtttct
    89821 aattgttata tctccttctt tcaaacattc aatatcaatt actggagcat attcttcatc
    89881 tacattagac acattattta gtttaatttc ccttgtatct ttgacagtta tgactttttg
    89941 aaagcttcta taagcataat ttgtatatgg ttgaaactct atctctaaca cacctttttt
    90001 atcttttgta tatcttttta ttatctttct cgctttgaaa tagtatattt cttctatgtt
    90061 gtcataactg ataaaaggtt taaattctct ctgccaaaac caattacata tgttttctag
    90121 cgtataatca tcccattcat aagcctcccc atgttcgcta cataaacaga attgtagtgt
    90181 tataggttct atagtagttt catcttcact gtaacaagga tttttattaa aactgctatc
    90241 agatttaatt gcttcttcat aaggcaatcc atattcattc agtatttcat catcacctaa
    90301 tgtaactaat ttgatgttca tagattcact tgagatatta tcaaataaaa acttatcatc
    90361 taaaaatacc aatttatcac cttctttcat ttttttaagt tcaaatccga ttaaaaccac
    90421 atttaaacgt aaaaaaataa tccctactca attaagagta gggcatttta ctatttctta
    90481 ggtttagtat ctttttcatc ttctaattca acacctagca ttgaagccat tctagcagga
    90541 ttaagatttt catctcctat aaatgtgaat gtagcatact ctttattttc atctggtaaa
    90601 acatctaatg tcatattaaa tccagatgga ttctcagcag taagatttaa ctctatactt
    90661 ctttgtgctt ttgcatttgg aacactcatg tataaaacca tatattcacc atccacagtt
    90721 ttaaccatta cctcagcttc tacaacgtaa tttggtgcag tagattcttc ttttattttt
    90781 acaacttttg cttttggtat ttcttctaaa tagaatactg ctactttatc tcccgcatta
    90841 aaatcggctg tagatattgt tatttctgta ttagctcctg taactgatga agtgaattgt
    90901 aatttcttaa ttatagatat tccatcactt tctatactat atacagatat gctatttgca
    90961 actggcttta tattttctaa agtaactttc ttagtactat cagatgttaa tacttttctt
    91021 ttcccaacct ttgcagtttt ttcatctata tcagaagata ataacatcgc taattgtgcc
    91081 atttgtatta cttcttgttc cattgttaaa cttgctgtta ttgctccatc aaaagctatt
    91141 gtattcgcac ctttagcttt tgcataaact gattctgaat ccagcttaaa gttaaaagca
    91201 tttaaatcct gtgaataaaa caatacttct cctgttactt tatcttttac tattacatta
    91261 cctgcatctt tcactgcaaa tcttttcata ttataaaatc atcctctcat tttttttgca
    91321 taaaaaatag cactgctatt taacagtgct aagtggtatt tttatctctt tagaccaatg
    91381 cttcatttta tccatatcgg tttgatattt aaatgaccat gcaaagccta aactttcatc
    91441 ataattttta aattgtatct tagtcttata agcattaatc aattgccaat aagtcatttt
    91501 taaaatcaca tccattgata tatatccatc tatattttga actatattta tataatcaca
    91561 taaatggtat gcttcttttt ctcttttctt tctttccttc tctttaaaat gtgcaattaa
    91621 ctgtttttct ctttcagagc cagtattttc aatccactta tcttcctcat ctttaaataa
    91681 attcttttta tcaatataaa acatttctaa aattaaatct gatactagtc caaaatcctc
    91741 tctacttata aaagcatttt tctttttatc atcaaattta attaaaatac caattttaat
    91801 cttattcata tattcaatat ttttaatatc agttttatat aatatagata aagatttttt
    91861 tatcttatca ctaagtaact caatttcttc agaagaatct tttcttgatg ttaacatcat
    91921 caaatctaag ataggtatag catcatattt acatttcaat tcaaatgatt cctcgttaca
    91981 tagctgagaa tagctctttt caagtactaa aaatggatta actatctcta aattagccat
    92041 atcaaattta ataagttctt caataatagg ttgatataca gttcctaatg tttcacttag
    92101 cttaattggt aatcctgtaa tataataatt ttccaacatt acatatcacc aaaactttca
    92161 gatgatacag ttataacaaa tccgttataa tcagtattta aattatacat ttgatataca
    92221 ttttctaact taatcttacc tataccagct atttcctcat tttgagttat aatatcaact
    92281 atacaacata ctaatgcaac atctcttaag ccatttgctg tattttggca ttcatcatga
    92341 caaacaacac caatttctat ctttgttttt ttaatttctc tacttccagt agtacatggt
    92401 ctatactctg ccattattat aaaaactgaa atatctgcat cttttaacac tttttctact
    92461 cttctattta gaaatacttt tttattttta agctctttaa caggattttt tacatcaggc
    92521 atggacaaaa tatctttttg ggattcgtca ttataaatca taaatttagc aaagtcttga
    92581 tttgacatta gagttgttcc tatattactt atcatcttgt tagggaaagc catatagacc
    92641 catatatcta cccccttagt gttatttttt tagtatctat tgtttcatta gtttctttat
    92701 ctttagctaa tagcaatact tctaatccag aatacttagc tagtatattg gcttgtatga
    92761 cacatttttt ttcatcttga ttaattatat tacaatacct atattgcttg tctaagagcc
    92821 atttaactcc tttggaatgg tctattctgt attcattttc ttcacctaga ttaataaatc
    92881 catcccctat aatcttactg aaaggaataa ttacactatc attttcagat aaatcattcc
    92941 aagcaacatt atttattgta tcatcttttg aaatcaatgc atcttgtaaa caaatagctt
    93001 taataagacc atctgctcct gtttctctgc cattatactc aaagtcatta atactagtaa
    93061 ctctaaatac agttttacca gttaacatta ttctagtgtc aatatctata gttttagtga
    93121 caggattact tccaaaataa agttgtcttt ttgtatctga gatagaagta tatttattat
    93181 ctgccatacc atcagagtat aaggttaaat tttcaacagc tatagggatt ttatacatct
    93241 gacctttata tttataatta aaaaactgat tgcatctttt tattatgaaa tgtttgtatg
    93301 tatccatttc tttatgttct ttaaatatag ttaaccaata acaattatca tagaaaagat
    93361 aacaacccac atctacatct aaatcagatt caactaatag atttttttca tctaaagctc
    93421 ttttatcatt attagttata tcattaattg caactatagc tcttttagta tcttctgtta
    93481 tacaaatttc atctatatca gttattggta cttcaataca ggttggtgtt tcttttagat
    93541 atttcttaaa acttaatcta agttgtaata ttcttttttc tttaggagtt gaacaaccaa
    93601 gtccaattct tttttttgta tcacttaagt aactcatgct agttccatcc ttcaaaattt
    93661 tttagcatgt atctttgttg atatttatta aatctagttc tcaattgctc ttctcttgct
    93721 tgaagtttag ccaacatatt agcacctgat ttagcattat aatcagaatc agttagcatc
    93781 tgttttaaat tttcttctct atttatctta ggttgtaacc aatgtatttg cataccatat
    93841 gataatattt taatttcatc taaatctaaa tcagatacta tttctcctaa atatttgtat
    93901 ttgaaaatta tctcttctgt agtttctaca acaaaactta ttataaattt ttcatcttca
    93961 aagcttattg tataatcttt atctaattcg tattcttctt ttgtatcttt tcccatcaaa
    94021 gttatctctg catttttatt actataatta gatgtataac ttaattgagc agcaggaata
    94081 atttctccac ctttttcatc aacatatttt atagtcaaat cttttttaca ttgattaaaa
    94141 tcaactatag catcttctaa ataactgtac atcatttttt ctattatttc atttgatagt
    94201 aataacatct cttcatcatt aataccatcc aaaaactttt tatatatttt tacaagtggt
    94261 gtacccaaat attccaccac ctttaactaa acaagtacaa atcttccatt ccaattcttt
    94321 tagctaatag tttagccttt agcccagaat caaacttttt ctttttatgt aaatctattg
    94381 ccctctcagc taatcttctt gttaactcaa cattattttt atttaatatt ttttcaaaag
    94441 aatttatatc aactttatca gataagaaat attctaaata gtcttcatta ggatttctta
    94501 tatattcata taaactattc aatcctagaa aatctattat gtccattggg gtacattcaa
    94561 catctaaaga atctacatcc gaaattatta atctatgttc ttcaaaaaaa cctggacttc
    94621 ttctcactat tctataaaga gtatctaaat ctataaattc agttgaatct tttgaaccta
    94681 ctttagataa agaaaaaatt tgttgttttt ctcttgggtc aatataatca acatcccatg
    94741 tggatatatt ttttatttct atatctattt cctgtttttt ttgttttagc tttctttgta
    94801 gttctaatcg gtttaatcta gcttcttttt tatttaaagt agactttata tctttttcta
    94861 aagtattagc tttgacttct gttttagaaa tattttcttt tttagctctt gccataataa
    94921 tctccctccc ataaaaaaaa gaaggtggat aaccaccttc taattcaatt attgtatttt
    94981 ataaactcca aatttagcag cagttacaac tcctaaatgt attttttgag ccataaaata
    95041 ttctatttgt tggtcatctc tttctttttc atcagtattt tctatgacca atacatctcc
    95101 ttcagtacca agtttgatta tcttctctcc atcaggtatt acatagatag ccttattatc
    95161 taaagcccac tctttacctt ctgctgcatt ttcatcataa gcatttggta aactaagtac
    95221 tttatatcca cctctaaatg tttgtataaa accatatttt cttttttctt ctttttctaa
    95281 atcagtttga acaccttcta aattacttaa tgcaagtgga gtaccatata taataggctt
    95341 tttaccagta gccccttcta ccttagctat caattccaat aatactttgt ctgaattacc
    95401 tgtagcttga aacttagcat ttattgttga atatgcacct tcaaatgtct tcgctattct
    95461 tctagcaata tcataatgat atgaatctga taccctattc acaaatacaa cccaatttat
    95521 tcttcctgtt ataaatctct ctgcttcttc atatatagca acagataatt taaatgctgt
    95581 tgtaggaact tttttattaa gtaatctttg tcttcttgta ctattaacac catctgctat
    95641 atttgcaact ttaaataaat tagtattttc aacagtaaat tcttttttat ctcctaaatc
    95701 aaagttctca aaatcacaaa acggactaaa tacttcctca tttaatctat taatatcatc
    95761 agatattaat tctgatatta aattataaaa tccccattta ttttcttgga atttataata
    95821 attatatttt tctcctccca tcatttcttt taatttattc tttattgcac tttcagcatc
    95881 tctatatgtt attgtgtttc catctctatc tgtatattct ctaaatgtat ctgtatatag
    95941 ctcatgagct attctcttta aagtttttgc tgttgccatt aatttacaca cttccttttc
    96001 tatttttttg cataaaaaaa taacagttat agactgttat ctcctgtttg ttaattttat
    96061 ttgattttat aaaactttta ttgtaaccga atcttgacct tcatagttcc ataattctaa
    96121 tacttctgct actggagttt tagcatctgc tgtaggcaat ttttcaaact gaaacgaatc
    96181 agattttaat tgtaacttgt cttttactgc aatactttta tctgctatat gtaatagaga
    96241 tatagttacc tcatctcctt tttttagtcg tctacatcta catatctgac caggagaaac
    96301 ttcgtaatct ctttcatcta atctttcatc atacatagtt gctgggtcat caactatacc
    96361 ccaatctaat gtgtcatttg taactttata tattttatgg gtatccctac catactccgt
    96421 gtcttcaagt tctccaatat ttattacagc accattttct aaatttattg gattggtatc
    96481 ctctgatgga acaacatatt tacctgttaa aacatcagga ttttttactt tatctgtttg
    96541 tattattgct ttatctttct tcatgtaaat tcctcctatt attctttatc tgaatatttt
    96601 tttataaaag atatttcttc tggttcacta aaactatcat tattattact tataggtatt
    96661 tttatcgtat tatttttatc atcatttata ctaaaatttt ccttttcgct ttgtttattg
    96721 ctaagagttt ttaatgcaaa tatgtaaccc aattctttct tgtattcatc taatgtaatt
    96781 tccttattat aagcttttat ttttatatct ttaatttcat cttctgctaa tttaaatttt
    96841 tgagctacat catcaacttt agatttaaat aactcaaatt ctttttcttc tttgaatgcc
    96901 tgtaatggct ctaaactggc ttttaaatta gatatttctt tttgcttttc agtaaatttc
    96961 tctattattt ctttttttaa tttttcttgt ctactaaaaa cctgtactat ttctccttct
    97021 tgtttttccc tccaagtttg tatatatgat tttttatttt cataatccaa aatgacagca
    97081 tcttcattaa ctatatatgg aataccatag taataccccc agttaatttc atcttcaact
    97141 atagcaatat tctcttctgg tattaaatca ttataataaa aagcttgtac ttcaactttt
    97201 tcaccatacc aattctcagt ttcgactttg tattctttta acttatttct tatttcagta
    97261 ctaagattac tcactgctaa agcatatcct tcagaatttt tattaagttt ttgattctta
    97321 tttggcaaat tcttttcccc ctctccatgt tctaatgcat aaatttctga gcatattttt
    97381 gatatttctt ctttataatt aatttttctt gaaaatttag ttaaacaaca atttgaaccc
    97441 atagctccct ttacatcaga accaagacat gtaattccat gatatacata gtcttttata
    97501 ttataaaatc catctgaatc atctaattga taatcattta tatctatttc cattgaaatt
    97561 tctatttcat cagaatccat aattatatcg taagcatgat tgctatatga tttatatata
    97621 tatcctttac atttaacata cttctgccca tcaatttcaa ctttttcata tttatttgtt
    97681 tctggtataa cgccaattat tcgttcttca taatattctt ctaatataaa cccttcatct
    97741 gtttgaacta cttgtgttaa aacattatga ccatcaaagt catattttcc atcttcattt
    97801 atttttacat atcctagaat tggaacattt tttaatgttg gttcagcttt atcaatagct
    97861 tcttcataaa atttagttcc atttggattt gtaccttcat gcataacata gatatacact
    97921 ggcaaaagat tactatttag ttcttccaat ttttttttat ctgaataatg ttttaaatta
    97981 caaggtaatt ttaatatttt tatttttttc acctcctttt aaaaacgtat tttgctagta
    98041 aatataaatc ttttcatttc ttcattactg aaattattta ttaattttga tttattttca
    98101 aaaacatata aagtcttatt attcaacttg ttttcacata taaaacgata tcctttttcc
    98161 attaataatt tcttatcatc ttcagaaaaa gcatatataa acttactcat aattaatcat
    98221 tctccccatt tccttttgct tgagtagaat taccattatc tgtccctata tcagatttat
    98281 ctggtctacc actgctttga gtatgagatg tttgttgagg tattaaaaac tcatcaaatc
    98341 ccattaattt ttctgcttgt aaagtgttta tagcttgaag tggagtaaac ccagtacttg
    98401 caataaacaa gcttttactc cctccgtatc ccatatcttc tcgatactgt ttggataaat
    98461 tcattttatt aaagtgagta gttccaataa acttcatatt aaataaattt gccttcttgt
    98521 ctttatttag ttcaaagtta acccaatttt ctatcatttg ttgaatcctc ataggaatta
    98581 agctatctgc aataatacca tttaagatag attcattatt tatcttgtca gagttaagta
    98641 aggctgtatt tattccagcg ttatcaaata taaactcttt tgcttctttt acataatcat
    98701 ttattttaga ttttccatct gaaagagtat gtgtttccaa ctctaaagga tttgtagtta
    98761 ttgctgttcc ttttggtaaa tttgcttttg ttgaattgtg gtatatggga attaaattaa
    98821 ggtctactag tggttcatca tttttgccaa atggtatctt ttgatgtatt aatttaatac
    98881 tttctattac tgcatttgtg ctttttaaat ctttcatatc ttcaagttcc attaaatcgt
    98941 caaatataaa gcaaaaaaat ggaactcctt tcactgaatc taaatcataa ttaaatgcta
    99001 ctgctttatc acttaattga aaatatgtat tatcaattaa ttcttctcgt gtaagtaaat
    99061 tagatttata ttttttatat atgtttttaa tttcttctgg aaaggatatt atgtttttgt
    99121 cagtaagttt ttttatattt atagcgtatc tcattacatt attttctatc attgttatca
    99181 tacaaaattt tgctggtatc tgttgtaaaa ccatccctga attatcttct atcttatata
    99241 aataaacctc tcctaattcc aatacttttt cggttatcca agctgatgta aattttatat
    99301 tatatttttc taattgactc gccgaattca tatatgcttt tgttattttt tcttttgttt
    99361 ttaatctact tatgtctttt gggtataaga tatggtcaaa agtattcata ttagatatta
    99421 aatttaaaac tcttctatat gtaccagatg tagcttttaa tatcatactt gcatcctgaa
    99481 gtatatctgt atttgaaatt tgatatggat tggagagagc ttttcttaat ttgtctctgc
    99541 ttatacttct taacttatac atttctgttg ctaatgttgt ggattctttt actgaggcat
    99601 attttccaat ttgagcattt agcatattga tttgattttg tgtagaattg ttgtctttag
    99661 acttgctttt attattattt tttttgccca cttattcacc tcatctctta ccaataaatc
    99721 ataacagttt tttgattatt tctatttttt cttttctctt tttcttccag ataatctgct
    99781 aagaaattcg tataagccaa actagaatat ctatcttttc ttgctccact tttttccttt
    99841 attttaattt ttcctccatc agcactatat tctaaattta ttaactcatt cactaaagcc
    99901 gttgtttgaa gataaggggc aatatatttt gcttctaatt ctgccttttt atctatttca
    99961 tctgccttta tcatttcttt ttctaatatc atttcttttg cttcaatatc acttatagga
   100021 agttctaagg ttctatttgt aaggacatct cttaaagaca tagccatttt atgattttca
   100081 tcagcgtaag ctttcatgga atatacaaca ggaagtgatt tttttgctag tgacttgtca
   100141 acagtattat cttcattaaa acatgtgtaa gcatcatacc attcatctct atctgaatca
   100201 taatttgctt tctgtatata gctccataca gttgttccta taccttgtgt atctaatatc
   100261 atataatctg cctgaaaatc tgaaaataat tgttttaatc ttattgcttg tttttcagct
   100321 tccataccat tataagcttc tatatggaca acacatcttt tatatgtgcc ttcatttgga
   100381 agcatcctca tcaaagtata aatagaatta tcattcttaa ctcctctggc caaagctata
   100441 tctgcaccaa taatccgtat ttctcctttt atcttattaa gatgatattt cttatctctt
   100501 tttttcttat tttcaagata ctctatatca ctaggaggat aaaacatact ttctaatacc
   100561 ctacatggat tcacccaaga tgacttgaag aaagcatcat ctgattcatt ataaaacact
   100621 ccacaatact ccatcatgaa agaagcatca ctcatactct cttttttcat ttctttaagt
   100681 attctttttt tagttaatag tccatgttct aaagagcaag tgaatggaat actacatgca
   100741 aacatatctt caccactaag catacctttt actgtttcca taaacttttt ataactccaa
   100801 tgctgagaat accagcctga actaagataa atttctttat tctcttcttg catatatcta
   100861 tatttaggat tctgtaaata tcctggttgt cttgggtttg ttaaaaatgg aactaaaaca
   100921 tcattcacag ttccttcatc caccattcta tattcatcaa caataagaac attagctctg
   100981 taacctcttg catcatcatt agatacaaca gcttctattc tacttccatt ccaaaaatct
   101041 atagatactt cttgtgcatt tacttggaaa cttttaattt ctcttttcag agtatctgat
   101101 tttaaatata aatcacctaa aattttactt gtaataagta gttttgcttg tttctttctt
   101161 tttgctgcta ttaaaacaca agtacctggt tttaatacag ctataacaca acaaaacact
   101221 cctagaagcc atgattttcc cagtccacga gaagcaataa atacaaattg gtcagacttc
   101281 atcatcatat aaattaatat ctgttgaaat aaatgtagat taaatccaaa gtaatccata
   101341 cagaatctat gtggatttgc gagataaaaa gcaccccaat actctcctat actctctagt
   101401 agatttcggg atgaatcatt agatgacagc tctctttttt catatttagt cctcattttt
   101461 attaccttct aaaatgtctc ttacatcatc tttaaattta atatctttat cgccatcatt
   101521 tatcgaatac ttacctgtag ctaaacctaa tgcaacagca agtggttttt tcatatgttt
   101581 atttacataa gcttcaaatc catctacatc ttcatattcc tttaacctat cctttacagg
   101641 ttgatttttt tcatatatca tcattttcat tccaaatgta tcatcttgcg aatctccagc
   101701 tttctttttc tgactaggct ttatttcagc atcttgcatt ttacttgata ctaatttaga
   101761 taaatcatta aaagctttca tatctccctt ttctcttgat ttatcttttt ctaattcaat
   101821 aatacaaatc tcttcaaaca attttctttc agttaatgac tctggttcat aatattcttc
   101881 atattcctta tattttcttt ctaagatttt atactcataa tcatcaaaac ctcttcccca
   101941 ttttaattta atttcatcat ttatgactat atttttatca ttattatttc ctgtatatat
   102001 ttctttcaat aaattatcta aagatgtctt tcccttatat tttgaatttc tattaataat
   102061 tttcatatat tcatctatta attcatcttt atttttttta tctgcaagtt ctttagctaa
   102121 tttttcatca aaataaacat caaagttgaa acatatatgt tttagtgcct ttacaagttc
   102181 tccattgtaa cacccattta atagtaaaaa cctagctcta aaacattctt tgcatactgg
   102241 aagtctttta tttaaagtaa atatttcact atgacttttc caaaaatatc tatctgtata
   102301 tttttcttca ccacaattca aacactttgt tttactaatt gccattcata acatcaccac
   102361 cattaaaaaa gaccactaga gaattaaatc tctagtggtt aatagggaga ttcaactcaa
   102421 ttaagagctg aattaaattt acaatataaa cttaactcag ctcttaataa ataacttata
   102481 gcttacttaa atttatattg taagtacata ttctcccact ttcattaaat atcattaatt
   102541 tttgcattgc gtgtgaactt aatcttagat tcttagcata agaatccgtt ccggagaaac
   102601 ttccatttac acatatttca ctttctccat aattatcttc cttacaattg tgtagatgag
   102661 ccataaagat ataatcagga attaatttta taagagaggt cagtttagga attgctgtag
   102721 acattttatc tttgtctcca tgtactccaa aacaagtatt tccacatatt ttagccacta
   102781 ttatgtcatt atcatatata tttttttgaa atataacatt gtttatattt ttaattctta
   102841 gctttatata ttcatctatt aataatgtaa aattatcttt atctaaattt tcatcttttt
   102901 taggaagaac tctatcatgg tttccaccta ttgaataaac aataatttta tcaatttctt
   102961 tagataactc atatataaat tcactaagta tttcagacac ctctataatt tgttcaacta
   103021 tattttctct attttctaat cttatagaat tatgtatgta tccagaaatt aaatctccaa
   103081 gtaacattac atgcagtctc ttaactttat gtaacttact atattcaata attttatctt
   103141 ttaaatattg tattcttatc ttgaatattt ctgaattata tctattaaat gcattaatag
   103201 tctctaatcc ataatgtatg tctgaaatta gcataatagc ctcttgattt gaagattcat
   103261 agcatttgta actagaatca cttagaaatg gcttatgaag tgatatatca tctattttat
   103321 tattaaataa atcaattata ttatctattc ttgaatattc tcttattttc ttatttacta
   103381 atgacctttc atcagataac tgtactttta tctttttcag ctctaatatt ttctcattta
   103441 ttttatcaat ctcttcttga gtagaattat cttgtacttt agaattaaga taatcaaaag
   103501 cctctttcaa cccataagaa accttcctac aatggtctgg agaacattct aaccctaata
   103561 gttcaactat ctctccccaa tccaaatcta tctctttatt aacctttgcc agtcgtattc
   103621 taatcctata gtcaattagt gactcatctt cttttttctt caatatgtct tccatattcg
   103681 atatctccct atttatcaca taaatatcat tatcaatgta ttaagtaaaa aataaatagt
   103741 ccaatattga tttatttaac tattgtttca cttaatctta tagttatatt taaatctgtt
   103801 tttccaatat actggtcaaa aacatcacta gataacactt cattatcgcc attttttgta
   103861 tgctctataa atttataagt accatcttct tgttttatta cttcacattt tctaaaatcg
   103921 ttcctttatt atttttcata tattttctcc tttattttta tgttatctat agctctactg
   103981 ggaatatatt tatttgcaaa ttaggcagcc ttgtagttaa caatagctaa tataagttaa
   104041 cgcatttagc atttatcaag gattttctat aactttttta ttttattttt actattttaa
   104101 taatttaatc ttttatcctt gagattttat atttgaattt ttaactttaa gctttatatc
   104161 tattgttctc ttttatacag tacaatcgtt tcgtttgtat gtacccatca cttttatata
   104221 agtagtttga tttttaaccc aaaatcaact gggaacttat aatttatgtt attcgcctaa
   104281 cctgcaaatt aaaaaatagc ccaattaagg actattttaa atctacatct ataattgtaa
   104341 gtgcatttga tgtactcaat gcaaaatcaa cttctttttc aaattcttct atttcatccc
   104401 ttaatttttc tattttctct cttactttta aagggtctac taaagaccat tcttgttgtt
   104461 ttttataaaa tgaaataagt tctgctccat ctttactttt ttctttttcc tcaaacattc
   104521 tgtctgtatt tttttgcact tcttcatttc tacgatttac ttcagacatc atacaatcat
   104581 agttactaac catttgtctc aacaaggatt tatctaattc tatactattt tttcttttta
   104641 ttgcttctaa aactgtataa tttttattac caatttgaac atttgttata gcattagaga
   104701 tattaattgc tttatctaat gcgttataat tatatattaa atcttctatt tgttggtatc
   104761 tacttgaaac ttctacatta aaatcttcta cacttgtttt tgtttcatat acatttttat
   104821 cagagccttt tttagtacct acaattttaa aattactaat gcatctatct atcttatctt
   104881 ctaataactt cttttctgct aaagctttat gaacattata tttaaccata aaaacatctc
   104941 ccttttaatt aagatattat ttaaaaataa caaacttttt ttattggaag agaggaaggg
   105001 atttgaaccc tcgtatcaaa ttaattgacc taatagttta gcaaactatc ctctttacca
   105061 cttgagtacc tctccatatt tctataaatt acaaacagca agtcgagtat cgctaccttc
   105121 gaccatggtc aagtgctgta ttttaaaact ccgacagctc ggatagcgtg gctgtttttt
   105181 cacactaaag aatctttttt aattgtccac tatttggtag aacatcacca cttttttata
   105241 aataaatcca cataaaaatt acttagttca aaagactatt tgatttattc acaatttctt
   105301 cagtttttta ttagccaggt acaccaacaa actcctctaa ttttaaaaag cagaagtaga
   105361 atctgttacc tcaaattcta cttctttatt cttacacctt taaggcatac tagggcattc
   105421 accgtatcta tttcaagtta tatgttgctc atcaacctcg tgtatatttg ccacgctata
   105481 ttcattttag cagcatcatc atcttatatt tgtaaaatac ctattaccag ccactagagc
   105541 ttctcaaaat gagctatctc tgctaattgt attaattttt agcatattct aggtttgctg
   105601 ccatatgtca ccatatgaaa gggattttaa cccatacact ctctatatga ttgcatcttt
   105661 taaagattta gctattttta attttggaac tcttttttcc tcagttttcc aaggtttttt
   105721 agttccatct ttaagagtta tttctccttc tttacctttt tgtattttag ttaggtattt
   105781 aactcccatc aacgtcaatt cttcaccatc ttgtagtact tcgtttcttt ttttttctat
   105841 cacatcaagt atctctctta ctcttatctg tgatacacct aattcttctg ctacttcttt
   105901 taaaaaatct acttttttca tatcttctta atctcccttt tcttatataa ttttcatttg
   105961 ataatagtaa ggaataattt tattattttt attaacccct tacataagta atatgtttta
   106021 agcgaccctt ttttaaacca cttttcccca ccagctaatt acagttttta caatttgagc
   106081 gatatccctt tttaccattt ttatcaaacc tagatagcaa cttaattttt ccacatctgc
   106141 tacatttttt atattttcct ttacaaacag atatataata ataattttct tcatagtttt
   106201 tctcatatgc atctattatt ttgttcacta ttttatttat ttgattattt attgcttgag
   106261 gagttatatt cattaaattt gaaataaact ctaatgattt atcttttcta tataaattta
   106321 aaatatcttt ttgtactgtg gtaaactcaa ttttagatat aatattattt aaatccataa
   106381 ctatacatgt taaatcatct tgcaaatcat tacccttttg aatctttaaa agctctttaa
   106441 catgtgattt atcaaacata tctaaatagt cccattctgg gcttcctgca tctgctaatg
   106501 gtgctttcca tataattggt ctctctatag aatttttaac atcagtcata tcatttttta
   106561 atgcatttaa atttttccta accattctct taagttttaa ctcttcttta cttaattgtt
   106621 tatgtcctaa ttctttatat ttagctttat accattcata agtatctgag tatgttttta
   106681 taattggata ttttttaata tctttaggtt taacttttat atcttttatt tttttatagt
   106741 ttttaggtaa ttgaaaaaat gcaaaggaat tgtcttctag gaatccatct ttattagaag
   106801 tgtttgaatt tatatttcca ccatttgcag gtgctatttt atttagaagt gcttcttcct
   106861 gacatgctct atcaaataac tcttttgaat tgtatattct tattttagtt tccttaggtt
   106921 tatcatctac tgagagtata tagctcccca ttatttctaa tgtttttgct atattagaag
   106981 tagaatatat actgtcatct ttatttaata tcaacttaat tttcgatgta ttatgatgtg
   107041 tgtactccca tgtaccatta ctattactaa aaggattttt aacatttata tattcgattg
   107101 gattaatttg attatagcca caccaagtaa tgaatctatt ataatccata actacttctt
   107161 ctccatcaat agtaacataa tatacaccat ctttatctaa aggactatct gatgtttgct
   107221 caaatatatt ttcccaaaat ttatcattga attgtttttt ttcttgatat ttcactctag
   107281 taataatatt ctcatttctc tttgtaagag tattataaaa tgtatctata taatttctat
   107341 ttgactcttc aaaccacgtg tgttttaccc ctaatcgttc ctctatgtat ttaattctat
   107401 ctttgctatt gtctatgcta taatctaaat tctttatgta atcttgtgca gatttgccat
   107461 ctatttcttc ataaaaattg ttattattat atatcaatat tatacctcct ttccttgcaa
   107521 tccatcatca taatctgtat catcataatc ccatagttca tccttaaaat cctccttatg
   107581 cctttcattt acaatatcat atgaagacct tttactcatc tctgtgtatg tatctatcat
   107641 ttgttcatat tcctcattta atatttgata cctattttta tgtacgcctg ttttctctga
   107701 ttcatctaaa tcttctaaat atattaattc tatttttttc tctttcatac ttctcctttt
   107761 ctatattata agattttaaa ttaattttct tggtcacatt tctgtgccgt ttttttgcct
   107821 tttggtcaca tttctgtgcc acccctaaat ttaatttttt aactgttttt cctatatttt
   107881 tgttaatttt tacagttcat tacctcttat tcttagacag actttctaaa tacaattaaa
   107941 aaagcataaa tcaattgttt tctttgctaa atttaaatta tttcccttcc atattacaca
   108001 aggatttata atgaaatagt ctgtattttt gttattccct tcaacgatta catatttaaa
   108061 aaaataatat ttatcatctt ctacctttat ataaaatcta agtaattcct ttttaaattt
   108121 gttcatatct tgttttattg tactaatatt taataattga caaattttat ataaactaat
   108181 tttttttatt tttgaaatat ctgtttcatg agggtttaaa cataagatat tactctcgaa
   108241 atgtatatat ggtatgagtt gatatatata acttaattgt ttatgttgtc ttggtgtgca
   108301 atgttcaaaa agaaatctac tagtatttat atatattctt gtatattctt tattttcaaa
   108361 attaggaatt cctttagtaa aatactttgg atttatataa aatttattat tagattcata
   108421 taataactca cattttttta cgtctgctaa aaaatttcta aatgccctat ctttaagatt
   108481 taatatttct ctcatgtttt ttctatctat aggaatcatt tctttaaact gagaatatct
   108541 aaccaataaa ttttcttctc ctgtattata gtttagatat gttgcgagat atattaatct
   108601 acttatatta gctttactta tatttacttc attaaataat aattcatttt taacataagt
   108661 acaaaataca aaacctccta atttaaaatt atggtatggt aattcttttt tattattgat
   108721 aatagccctt tgctctggag aaaaactctt ttttctcttt ccaatttcaa gtacctcacc
   108781 tcttttcatc cctttatgct ccaatatttc tcctgttctt ttgtctgtta caataacatc
   108841 ttttataaat tcattacctc taactataaa tatctacctc ttttcttata aattttattt
   108901 caattacaag ataaaaacca tcttgcaatt gttcttcgca acatgttgct tcataaattt
   108961 tattaccctc tatgttctat ttctattata tcatataccc tctatgttct caatattttt
   109021 tttaatatct acccaaaatt tcttgagtag atattttctt ttaatctggc atattattaa
   109081 atatattctt aataatagga ttttctcttt ttatatcttt tttttcttca gtaacatttg
   109141 tctttttatt tgtcctatat acaccattgc ctaaacattg ttttaataat ttattttctt
   109201 cttgaagatt tttccactct aatattattc tttccaaagc tgtatttcta ctgcttatat
   109261 ttttatcatt ttgatacttt tctatttcac caaatatatc ttcttctaaa taaaagctag
   109321 atgatttttt catataatat cactcctaga attgttccat acctacttca aataatcctt
   109381 tagctgtagc catttgtgca tctttagaaa ctttaaatct attatcgaat gtcatatgta
   109441 atgctgtacc tccacttaca tatacatcca tttcatctat gttcttccat ttagaagata
   109501 ttctttgagc tgtgctttca gaagccataa tgtaagcaac tttcttaagt tcatcataat
   109561 cattagaact atctatctca ttaagctctc ttattattcc tctatctttt agttgcttct
   109621 gaaccattgt taaagcatct tgatttccag cttctaatgt gtctgatagt ttatcattaa
   109681 atacaaaacc tttttcaaag aaagacatct cagtacttct aaaacctatt gaaaccatgc
   109741 caaccgcttt atcttcattt acttttcctt ctaatgtatg aaataatgca gcgtctcctt
   109801 ctctaaaaat tgatatatca gatattttta tttctttatg tccacctttt attttatctt
   109861 ttactttaaa tgttttacct ttatatgtgt ctacaacttc ttttaatgtt gttttcctaa
   109921 atgatttata tggaacgccc atcatcaatt ttacttcatc agctacagct atttcattaa
   109981 gagcagcagc aactaatatt ctcattgtaa aagatacttt agaatcatca gaatttctta
   110041 taggtgttat actttctttt tctgctaatg aaccaacaaa gtaacttaca ctttcaaaat
   110101 ctatgtatat tggattttca tatttctcaa aatctatgtt tcttccatca ccaaatactg
   110161 atttgaataa acattcttta accattccat tgtacttact atatcctttt acgtatcctc
   110221 ttcctatatc taagcctata acttggtaat tttcttccat tttcattcct cctaagtaaa
   110281 tatttgctaa atatattata ccatataaaa acttgataat tacattaaat ttgcacaaaa
   110341 attcaactat aaaatgacat tttttagtta ttagttaaaa ttagcactaa attagaacta
   110401 tatataattt aaatttaaac caacaattta ttattaaaat tttttagtta atatttaaat
   110461 tatatatcaa ctatttccaa accaataaat caatttcttt aactatacta tttatgtttt
   110521 tttagatgtc aattttaatt ttaagtaaaa tattgaaact tattttctta cagacgacat
   110581 tttcattcta atttaataaa tcttcctata tttcaagtta ttttttgtat ttaatatttt
   110641 tatatgtatt agttattttt atgtaatcaa tacatacact tttattttat attttccttg
   110701 ttgagaatgt aatttaagag taaaaatcta agaaatatct ttagataaat atttgtttta
   110761 tgaggaaaat acagagctat ttcgtctgta aatccgtctg caattttttt gaaatgtgga
   110821 aatgaaagga ctacacacaa aatcctactg acaaacaagc cactttccat aaaatacccc
   110881 ctacttcatt tttatttatt ttaatatgta aaatacttta tttactttat ttaattaata
   110941 aaagtattac ttttatctta ttttaaaaat ctatgttttt gtcagtaaaa aaggacataa
   111001 aaattagtat tttatgccat ttttctaaaa cctagtattt tcaacactta caacacctac
   111061 actttctatt ttgtcagtaa aatgtcagtc attataattc ttagactaca aacctgttgt
   111121 aatcactgca tttcaatttt tagttattga tatctatata aaatattatt tgctatagaa
   111181 taaatttttt tattatggat tataaagtct tatatacatc attttagcat taatctgaca
   111241 tcgtcgaata tcaactcaca acctcattgc catatttttc ttgacaaatt tgtcattatt
   111301 gtatataatt taattaagat aagaattaat cttatctata caattcaata ttagggggtg
   111361 acgttatgag aataacaaaa ggcaaaataa aagagctaat cgagttgtgc caccaacttg
   111421 aaaagctctt tgtacaagta tttaaatcac ttgaacatat tttgatttct ttatgttctt
   111481 gtatcggttg gttattaata cttatataca taattaaaca ttaataacca atgcaatata
   111541 cctataaaaa tatatctcta taggtatatt gtaacacacc taatattgaa agtaaacgag
   111601 gtgacgacat gagtcaacat attaaaaaca ctttaaaaat aataaagata ctaggtttat
   111661 tattcttctt atattttgca cttagagcaa tatatattgt ttatctttaa tatctttatt
   111721 gagttgctta atgtataagt aactcttttt tgttataata ttaatgaggt gatagcatga
   111781 aattagaaaa attaattgat ataagaaaag aaaaaaaata ttctcaagag gatattgcta
   111841 gaatgttaga catatcttta agaaattatc acagaaaaga aaaaggagag aatcaattta
   111901 cagtaagtga actagaaaaa atatgtagct atttagatat agaatcaaaa gaactacttg
   111961 acatatagta atataatcta ctcaaggtag tacttaacat taaataaaat aatttaataa
   112021 tataaaatag actagctata atctagtcta ttttattata ataacatatt gtacaagcca
   112081 tttaaatcca ttctaagcac atttcaatgc attcacctta tgtttatacc tttaatcttt
   112141 aaaattaaat ataaaaataa gctagacata tatactctag cttacagtaa tttttttaat
   112201 gtgttgactt gttcttgtac tattgtttta ctcttagtgt ctaactctct ataattattt
   112261 aatagttgtt tttcttcttc ttctagttgt atattttctc tattgtctgt aagacataat
   112321 atataatcta tacttacatt atatatatta gataatttta taagcgtctc attgtcaatt
   112381 tttcttctgt ttgtttcata gttttgtatt gttacataat gtacgcctaa tagttctccc
   112441 acttgttgag ttgaatatcc tttttctttt cttagctctc tcaatctatt cattaaatca
   112501 cctcttaatt ctaaatataa catattataa atttaattac aattgtattc aaaacggtat
   112561 gttttatata tgacattatt taaaacattt tgttttgttt tttatatttt atattgacaa
   112621 tcaaaacatt ttgttttata attaaatcat agcaagggag aacaagaaaa cacaaagcca
   112681 cctctcaaat gaagtaacag gcaaagaacc ttcttaaaac tctagctaat atcttaaagg
   112741 gttctattaa aaaatattaa actactatta aaaaattact acctttaagt tgacctttta
   112801 aatggtgtga atggtgaaag gcacacaaca caaatattac acatagtttt ttcttcattt
   112861 tttaactaca aaaatgaatt agtcatacca gttggtgagg tgttcccaac attaagtaat
   112921 taaataaata aaattaataa aggtttccaa ttaaagccta caaaaaattg aggtatcaac
   112981 ttagttgctt ctataatggc actcaataca atttaatatg acatagcagt tgtgaggtac
   113041 tgcgttataa aaagtactaa agattgagca ttaaaattat agtttgtact gcttgacacc
   113101 tacatggtta taaactatct aatatttact agtataattt aaactattta ttagattatt
   113161 ttagtaagtg ttagaataca acacttaaat tatgatataa taataaaata ggagtgtgaa
   113221 cggcatggat gaaaaaatat tagaattatt acaaaaaatg gatactagta ttaatgatat
   113281 acaaggagaa ataaaatgga ttaatactag actagatagt atggatggtc gttttgatgg
   113341 gattgaaaac caacttagtg atttaaaaga aggacaagaa gaaattaaaa agaaactaga
   113401 cttaacttat aatcaagttg ctagaaatat ggaaggcata acagaagttg gagaaaaaat
   113461 agacacttta aaaaatgaca tgaactttgt agaaatggct acatctaaaa attggaatga
   113521 aatagcaaag ttaaaatcaa ttaaatagga gtagataaaa tggatgagaa aacattagaa
   113581 ttgctacgag aaatacagga aagtattaaa attttaaatg acaagcttga cgaatttgat
   113641 tatacacaag ataaaataaa atctaatgtt gagggacttt tagaatgttt tagtcgtatt
   113701 gattttagaa ttgaagacct agaaaatggt caaacctcat tgtatactaa gcttgatata
   113761 gtgcaaaatg aaacagcaaa atcaattaaa tagcagtaca taaaaagaca cttgaattat
   113821 tgagtgtctt ttctacaagc tcttagtatg gtattattaa acaataatat cattggaggt
   113881 ataacgaatg tatgagcaga gaaaagcaaa agtaatattc aataaaggag ctggtaattc
   113941 taggggagaa tcatatacga atagggttac aattccaact acatggataa aacatatgga
   114001 cataactaaa ctagacaggg aagttttgtt gacttttgat ggtaataaaa tagtaataga
   114061 aaaaatagat gagtagataa aaaatctact caaaaaaata cttgacaact cgtgacgagt
   114121 cgattgtaat taaatcataa aataaaattt tttacaaaat gactagtaac gagtcggtaa
   114181 aaagggagga tataaaatgc taaatatata cataactaat ttagggaaat atgattgaga
   114241 tgccttttat atagttctct aatatggtat tattattcta taataataat gttggagggg
   114301 acaaaatgaa tttagagaga ctaaaagagt taaggttaga aagaggatac agtcaacaac
   114361 aatttgcaac ttatattgga ttgtctactt ctacatatac agataaagaa gcagggaaaa
   114421 caaaattcaa ggttgaagaa ttagagaaaa tattaaaatt tctaaatctt gaccctttgg
   114481 aattgcttga cttagattaa aaagtcaact tttctaaata ataaaaccga aaaatcgttg
   114541 acaatatccg ttttgagatt tataattaaa atatcaaata aaaaatttaa aaaacaaaac
   114601 cgaaaaatcg ttttaaaaaa tcgttttata ataaaaaagg aggatataaa aatgctaaat
   114661 atatacataa ctaatttagg gaaatataac gaaggtgaac taatagggga atgggctgaa
   114721 cttccagtaa acgaggaaga attacaagaa atattagata gaatagggat aaatgaagaa
   114781 tatgaggagt atttcataac agattttgaa acagatatag aagggttaga aataagtgaa
   114841 catagcaata tagagcaact gaatgaatta gcaatgaaac ttgagaggtt agaagaatat
   114901 gagattgaag agttaaaagc tttacttgaa cgtggataca ttgattttta tgacatgctt
   114961 gaaggggata tttgcagatt atcaggtaat tatactttta tacaacttga tgacaggtca
   115021 ccattggatg atgaaaattt aggacgtagt tacatagaag aaatatgttg tggtgattta
   115081 tcttgtatag aaaatattgc ttactacttt gacatagaag cattttcaag agatttacgt
   115141 tttgatagag atatgattat tgaaaattta tacgaagaag atatagaata ttatgaaaat
   115201 atgacagata ttgaatttgc agagaattat attgaacgat taggagatat tgaagagtta
   115261 ggtcaagaaa cacttgaaag atactttaat tatgagctat atggaactga cttacgttat
   115321 gagaatattt gtatagcatc aaattattta gctatagttt cttaaataaa aagttttagg
   115381 gcgttcttta aaaacgccac ttccaataaa aaaattgaaa ggggaataaa tcatgaaaaa
   115441 attaataatt aagataaaat cattgtttaa aaaggattta gatagtagct attggagtac
   115501 tacagaaagt attattttaa aatgtggaaa cagcaatcaa ttaaaattat tgaaacaatc
   115561 taataaatta taaaggggga ttattaaaaa tgaaaataaa tagcaaaata tcaaatgtag
   115621 tatgggacat aaaaacaaaa gagttaaata agcaggatat actttttata gaaaatttca
   115681 acccaacaat atatcataat gatgttgatt gttacctgtg gtcacttgat gaaaaactac
   115741 caagtggtgt atggttggaa aatataaaat ttaataatga aataacagaa gctaaagcta
   115801 ttgttttata aaattcaatt cttaagatag atgtaaaata ttaggagggt taaaaatgat
   115861 aaattattct aaatatatga ctgcaacaga tttaataaat atatgtgaca ttttagaagg
   115921 tgaaacaata ggagaagcag gaacttataa ttccttaagt actagactag gaaacttaat
   115981 cggattagat tgggctttaa aaggagaaga attgagacag caattaatac aaaatattaa
   116041 taatatgatg tatttagata atgaaaataa aattcaatat aaagaatttt aaataaaaaa
   116101 taattaattt ataggaggaa aataaaatga ataaaataat cgtattttat gatatagaag
   116161 ggtatccagt tttccaaata cttgtaagaa atgtaaaaaa atatactaga caaaatagaa
   116221 tatttaaatt ggttgatagt tttattaaaa aaaatataaa taatattaat ttaaatgatg
   116281 ggaaaatata tgatagctct agttggataa tttttactat atcaaaaaca ggacattata
   116341 aattaaaact taatcttgat atagactatg atatattaat taaaaagtta gatatcaaaa
   116401 aaagtaaaag agaaagtaat tctaaaacag agagagaatt attttatata ggaacaggat
   116461 ggtgtaaaag aaaagaaata tacaatttac taactagaca aaatcaaatt ggatacgaag
   116521 attatgatac tttaacaata gatggcgatg tttatataag aacatataat gaaaaatgta
   116581 gaacaatatt acttcatagt aattatcaaa aaatattaaa agagatataa ataaaattca
   116641 acttttaata taaatggagg gtttaaaatg aataagtatt taattggttg cataggtaat
   116701 tgcttaagaa gtatgaaagc aataaaaact agattttttt taatagataa taataacatt
   116761 gaggatgtca cactaaagtt gtgtaaagga gtagagcata tagcaccatt tagatataaa
   116821 tatggattag caaattatag ttttggttgt ggtttatctc attatttaga tacatataat
   116881 ttaaacactg taaatggatt agatttgaat aatacacatt taataatgct tactttaaat
   116941 gatttaaaaa atatagtagg gtgtaaaact gtctttgata tagatgtaga agaaaaacta
   117001 ttaaactata taaagagtta ttacagatga aaatacaagt acttaaaata ttaattttaa
   117061 tataattgga ggggattgaa atgttaataa ataaggctaa aggtattaaa acatcacttg
   117121 aaacaagcag cttaagagaa ctaaaaggat acataaaaga tttaagaaaa gcactatcag
   117181 gatataaata taagaataaa atagatgaaa ttacagaata tcaaatagat aaattgtgtt
   117241 acaaaattga taatacagat atatttgact tgaaatataa agaaatagaa aagtatatag
   117301 ataacttgat tttgataatt aattttatct ttatggaaat gtaattaaaa gaatgatttt
   117361 aatataattg gaggtttaaa catgaatgag tatattttga taaattatac aaaaggtaaa
   117421 ggagcttgtg accactgtgg aagaactata aaaaatatag ctacaataaa aaataatgtt
   117481 acaggagaag tttttcatgt tggattaaca tgtgtagaaa aaataatgaa attgaatgtt
   117541 acattttaca aagcattgtc gagagagata aaaaaacatt acaaatgtat ggagtactac
   117601 agtaagggtt tagatataga gacaaatctt aataaaatag tgaagaataa tactaaatac
   117661 aaagaaggtt cttatgctta taaatctaat gaacaaatgt tagaagatgc aattgcggaa
   117721 gtggcttggt ctttggctcg tatgatagat agttgtatga gaatgaataa acttagtaag
   117781 tctggattga tagatataga tatattaaac agtttgttta tcaagtataa ggaatatatg
   117841 agtaaatttg atgaaaatta caataaaaac aaatataaat ataaaagttg ttatactatg
   117901 aaacctttaa aagtaatatt agatgaaaat gaagatttaa aagaactata taaaagtatg
   117961 caataaatgt atgtaggcga tgaattaatg acaatgaatt ttatatagat gaggattata
   118021 ttttatataa aagagtgtca tatctttaat ataggacatg aagtaataaa agagtttaaa
   118081 attatatttt taataggata tatgagttat caaatcgcta ttattatagc tatattatta
   118141 taattcaaat gataatgata gtgatttgat aaaaggattt taaagattat aaaaatcaaa
   118201 aggtataaat acattaagat aattttcaaa cagcttatag aggcttgtac ggggtcataa
   118261 tcataaacta ggagggtgta aaaatgaaat tcaaaaatat agctatggga atgttattag
   118321 gtttaattat tgttggagtt gcaggagcaa caaaagttaa ggctgccgaa ttagataatt
   118381 tttatgtaga aactaccgac agagttgtag aaatattaga agatgaaagt gtagttttat
   118441 atgatactaa agagcaagtt tataatttct atccagtttg tctaggtgac tggaactata
   118501 gctttaaaaa taaaaaagat ttagatagag cagttgcaac ttacaaagag ctgtcaaaca
   118561 atataagtca ctcaaaggat gtatatgtga ttaataagtt aaataacaat ggaaacatta
   118621 aagtattttt aagtgatgga agttcaattg tatatataaa aaatgataat aaatattatt
   118681 tttatccttc ttgtatgggt gattggtatt taacattaga tagtaaaatt gatttaagta
   118741 attgtgttgg cacttacttt gatgttgagg ttgcaatatg atacgatata tgaaagatat
   118801 aaataatata agtttagaag atgctgatat gttagcaaaa gagggatttt gttttattat
   118861 aaaagatggt aaattaagag gttttaaaat tgaaaaaata aaaatagggg gatatgaaaa
   118921 tgaaaaaaat aactaagaaa gaaatcaaaa aatatgtaag agaagctata agtaataatt
   118981 ttaattggga aatagataga tgcggatttt atataaaaaa tgattcaata aagtttttta
   119041 tttcatataa aggacagggt gcagacgaaa atatatacaa caatacttac gaagaaataa
   119101 tttacattga tgatattata gaagactata aaagaaaaga atataattta aaagatgtag
   119161 attcaatagt gcatgaaaat gtaaataata tgattataga ttacaatgag gaaatagaag
   119221 aaaatgaaag atgtataagg agctttataa aagaactaaa aagttctgta ggtgaagagt
   119281 ttacagtatt agaatatgat aattttgtac aagaaaaata taattatctt gttaataaaa
   119341 ctgactcatg ggattttttt atggaaggtg aagtatataa ttatttagat tgtggaagtt
   119401 atacatattc aggattaggt aaagattatg atgttgatat aaatattgtc tttgatgtaa
   119461 taaaaataaa ttcagaagaa gattataaat ctataataaa aataaaagac attgaattgt
   119521 tataatttac tatatatcta taatatttaa atatgaacta atgatataat taaaattaaa
   119581 agatattaaa tttaatatct tttaatttta attgataagc gaggtttttt aatgaaagaa
   119641 gaattaaata tagtaccatt tttagctgag tctttgtcga taaataaaaa atgctataaa
   119701 ctcatagata aatattataa tgaaaataaa ttaaaatatt caagtttggc caaagataat
   119761 attttttata attcaaggat agcaagtgaa ggaagtataa ttcaagaata ttattttaaa
   119821 aaatctttag gtattctatt agaaagagat gaaaagaaaa taacaaaaat atttaaggtt
   119881 ggttatacaa ttgcttacaa ttatattatt tctatccaaa catttaaagc aagtaccttt
   119941 ttaagaaaac ttatgttaaa aaataaaatt gaaagttttt cagaggatga attaaatggt
   120001 aatatgttag ttgcaatttc tttatgtgga gctttaggga aagaagttga cgaatcagat
   120061 gaaatatata taaaagtaat tagaaatttg attctaagaa atgaaaatta taaacatgaa
   120121 aaagttttat ctatagatag actaagtaaa gatgaacaaa aactcattag taagatagaa
   120181 ttaagattaa aatctacata tttaaaagaa tatattccaa gctcgtatac aattggaatt
   120241 gatgggagta taggaacttt taatttagat gctttaacag atttagacag aaacctttta
   120301 ggatttgatt atatatatga cctggaagaa ttaagtttaa tttcaattgt aggaagagac
   120361 atacttaaat ctaaacaaat acaagaatta attttatgtt actgtaattt acaaaaaaat
   120421 atagaagatg aaaatagcat taattatgag gatttattta aatttataat tcctgctata
   120481 gacataagat atttggcaag agaatataaa aaagctaaac aatttttctt taataatttt
   120541 gatgaagaat taaaagaatc tatagaagaa aaagacctta aattggatag tattaaaaaa
   120601 gaaaattcat tattggaggc agaaaatgaa aagttaaaat cagaactaga attgttgcaa
   120661 aaagataaac ttagattaga aaatgaaatc aaagcacaac ttacatctaa agaagaattg
   120721 gttcaattaa gaaattttat gttcaaccag caacaagagc aagaagagaa agttttaatt
   120781 gatgaaagta taaatttaaa aaatataaaa gcaataatat ttggtggaca tccaaattgg
   120841 attttaaaaa tgaaagaaaa attaactaac tttgaattta tatcagcaga tacaattaat
   120901 tttaatgtaa acatattgaa tagttatgag tatgtattta taaacactaa ttttatagga
   120961 catgctatgt actacaaaat tatagaaaat ttgaacgaag ataacaaact tagatatata
   121021 aataatataa atgtagatag agcaatagaa gctattaaaa atgctattaa aatttaagga
   121081 gcgtattatg attgatatag atataaataa aagaataaaa gaaataaggg aagatataaa
   121141 tttatcacaa caaaaattcg gagaaaagct tggtgtgagt agagatgtta taagtaatat
   121201 agaaaataat agagtagaag ttaaaacagt atttattact catatgtgtg aggtttttag
   121261 tgttaatcaa gtgtggttag aaactggtga ggggaggaag tttattgaac aagaatgtga
   121321 tattgtttta ggagaagttt ttgctaatat aactgtatct aaaaatgaaa atttaaatga
   121381 attgattata aatatttcta aattaaatga tacatatata aataatttaa atgagattgt
   121441 aaaaggtcta atttaaatag tgggaggtat tataattgtc tgatgaaact ataagtaaga
   121501 gaattagaaa gataagaaaa aatgctaatt tatctcagcc agatttcggg ggaaaattag
   121561 gtgtcagcaa agatgttata agtaatatag agtatgatag ggttgaaccc aaacctttac
   121621 ttattaatca tttatgtagt gtatttaatg ttaataagga atggcttata aatggtacag
   121681 gtgatatgta tgtttctgta aaagaagata tttcttcgat tttaggagaa gtgttctata
   121741 agatagctag ttcaaaggat gaaaatttaa aagaactaat aattaacatt tctaaattag
   121801 atgctacata tatagcgtct ttgaatgaga ttgtaaaaag gtcaatacag aggtgatatt
   121861 aatgtgtgat ataggcaaga gaattaaaat cttaatagaa aatgaaaaaa taaaacaagt
   121921 tgagtttgca aacaagataa aagttgaccc atcttatata tctaagtttc tatcagataa
   121981 atctaaagta atacctagcg atagattaat agatgatatt tgtagtacat tcaatgttaa
   122041 taaagaatgg cttaaaaatg gagatggaga aatgtacata gagaataagt gtaataggaa
   122101 tatttcagaa gcgactgact tattaatgga actttcaatt gaatttcaag aatgtgcaat
   122161 taatcaaatt aaagacttaa taaaattgca acattcatta aaaaagtagg agagattaat
   122221 gtctgaaaaa gatgaaatta taagattaaa tttaatagaa ttaagaaaga ttttaaaata
   122281 aaaagagtga tttatatgaa aaagtatttc aaagaagaat ggaactatat tgctgatgca
   122341 ggatatgaaa tagacaacat agaaagtact aaaataatgg taaataattt tgaagtaagc
   122401 ataaaaatga gtgaagattt taaacataaa ggtgacatag aatatacttt taatatccca
   122461 tatgaccatg aaatttttac aaaagagtac aacgaagttt tgaatttaga acaaccttgc
   122521 gattgcgacc aattttgcga tgaactatca gaccttagag caaggattga agaaggcata
   122581 gagaaatatt taaaagacaa tgacaagtta aaagaaatag aatattagat gtaattgaat
   122641 ttattttaaa aaattataaa attgaatata aaaatcataa agctgtattg ttataataca
   122701 gtttttttaa tacaaaaata cagatatatc ttgaataata ttttaaaata ggaggaaatt
   122761 aatatgggta aaatggataa aaaagaagct aaaaaatttt taaaggttgt agatatgaat
   122821 atagataaaa taaaggaaga agctacgaaa atttataaag aatgctactt aatagaaaca
   122881 actgatacta taagaatttc tataaatttg aaaggagttg taaaaagcac aatttcaagt
   122941 tggcaaggct attcagatga tatttttaat atgagagaaa ttattgtcta tgaatttagt
   123001 caaggagaag ttcaaattga agatctttta ggagaacttt gttttttaaa tgattacgaa
   123061 gaatttgcta cttggtgtga cactgaaagc gaaactttga attggaatag ttatgaaaaa
   123121 ttcaacaaag aaaattttga cgaattagtc gagagaaata tagaagatag tttaccagat
   123181 tttttggaag aattgagcga aagtatagaa aattgtaaac aagaattaaa atcaatgatt
   123241 gaaatttaaa tgaaagagta ttattattaa tgtatatagt atctttaaga ttaactacga
   123301 gggatttaaa atatttttta atttatttag aaatgatatt ataataagaa ttttcagatt
   123361 aactacaagg gatttaaatg tcaatttaat ttatagagaa atgatataat ggcaattttt
   123421 tagattaact ataagggatt taaatatcaa tttaatctat atctatatga tataatatca
   123481 cattatttta tattaactat gaggaaataa aaacagtgca ttcagataaa tacactgttt
   123541 ttttaatgct aaaattagtc attatgataa cttaatcctt cgattataaa tcctatattc
   123601 gtcgtcattt ctgcttcatc actttgtaat attccttctg taaattcgct atcgcttgat
   123661 aatgttattt ttttccttgc caccatttcc aaaattgttt gaaatagttt aattttcata
   123721 ttcttatcaa gtccagcata ttgcaaatag tttgctactt cttgcgaaaa tttagttaac
   123781 tctgatttag tcattttttt agataattct tttccaatgc ttagataaac ttttttagat
   123841 tgttcaacat ccattttttt caaccccttt ttagattata attaaattat attttaaaaa
   123901 tgctaatact tcaaatataa atatttttgt ttaagtataa aactgatttc aataattcgg
   123961 attttatatt taatagattg tgttacttaa agttaataaa taaattagaa agatgtatgg
   124021 tactaaaatc tagtaataag ttaaagtata acagcacttt agggttaatt ttgtagtaag
   124081 tatataaagt caatatacta aattacaata aaattgccaa aaagccctct cctttaggtg
   124141 tagggatgaa aggtaaggtc ttaatataaa aaaagttaga ataatgcttg taatctaata
   124201 ccactactga taccctatat ttaggaggtg ttagttttta tgtataaatc taacgaaaat
   124261 atagtttatg attgcaaata tcatattgta ttttgcccta agtatcgtaa acctgtttta
   124321 gttggcgaag ttgaaaagat gttaaaagaa atactaccat ataaagcaga tgaacttgga
   124381 gcagaaataa tagaaatgga aactgataaa gaacatgtgc acttattaat atcttgtgac
   124441 cctcaatatg gaattcataa agtagtaaaa ggtttaaaag gctttagttc gagagtatta
   124501 agagagaact ttccacattt aaagtctagt atgcctagca tgtggactaa tagttatttc
   124561 gtaggaactg ttggctctgt aagtttagaa gtagttaaac aatacataga caatcaacca
   124621 attaggagta agaaaaaatg ataaaaactc atagagtaaa attaaaccta actagaacac
   124681 aatttgaatt aataagggaa aaacaaatgg agagtgctaa ttgttggaat catatagtta
   124741 acttatctaa agaatactat tttgaacata aacaatggat taaaaagaat gatatacaaa
   124801 agtcaatcaa aggtaagtac aatcttcata gtcaaactat tcaagctata tcagataaat
   124861 ttgatgcaaa tagaaagact atatcagaat taagaaaaaa aggtaatact aaagcaaaat
   124921 atccatacaa gactaagaaa ttttatataa taccttttaa agctagtgct attaatagaa
   124981 atgctaaagg caacttaaaa ttatcaatgt caaaaggcag gtatttagaa ttagatttta
   125041 atgttgagaa tataaaaact gctgaaatag tatggcgaaa cggatattat ttatactaca
   125101 cttttgacaa tgaattaaat ggagttgtag ccaaaggcac caataccgta ggtgtagact
   125161 taggggaaat acattcgata gctagtgtaa caaatgaagg tgtagggctt attctatcta
   125221 atagagaagg cagaagtatt aaacaattta gaaataagat gtatgcttat atatctaaaa
   125281 gattaagtaa atgtaaaaaa ggtagtagac aatcaaagaa gttatggaga ttaaaaaata
   125341 agataagaag taaaacagat aatcagttaa tgaatttata tcatcaaaca actagaaagt
   125401 ttatagactt ttgtgtggag cagaaggtat gtgaaatagt tcttggggat ataaaagggg
   125461 ttgaaaaaga tactaagaaa aagaaaagat taaacagagt taatagacag aaaatatctc
   125521 aaatggagta tggtcgaata aaggactata taaaatataa agcaaaagag caaggtattg
   125581 aagttaagtt agttaaagaa aactacactt ctcaaacttg cccaaagtgt tctaaaaaac
   125641 acaaaccaac tggtagaact tatagttgta cttgtggtta taaaactcat agagatatag
   125701 ttggtgcttg gaatatttta aataaaaagc ataaatatgg tttagtagat tttagaataa
   125761 atcataagca accaataaat ttaaaagtat ctaccgtttg agccatgtgt gggcgaataa
   125821 ctttaaggta gtagtggcga agacaccgtc cgaagtagct tggctttgta acacacctct
   125881 gttgtactgt ttaagtataa ataagtgcgt tagccaccaa gaatcccctt gctttaacta
   125941 tggggagtgt gtcaattatt aatagacgta atattgtaaa aaaatgatat agtttagaaa
   126001 gatatgtaga ttaaacgtag aattaaaaga ttaacatagt atgacaatca taatctcgtg
   126061 tagtatactt aaattagagg tgagtatatg acttggaatg atttaaaaaa taatgatata
   126121 acatatatag ttgaatatat taatagtaag ttaaatgata gtaagagttt gactaaagtt
   126181 gctatagagc ttggtgtatc tgaaagtagt ataagaaaat atctcactaa aagaggttat
   126241 aaacgtataa atgatgagta tgtgtttatt ggtgacaata gtatgacaaa ggtagtaaac
   126301 aacagacaac agagtaataa tgataataga tttaatatga caatagaaga tgacaacaat
   126361 cacaacatag taattgacaa ccaatttaaa aataatataa tctctttagc aaaagactat
   126421 gataaaatac aagatgtatt aaactggttt gagaataaag aagatacaaa tgtaatagaa
   126481 gttgtacagg atggtattaa aattgattta ccttcaaaag atgctataag aactacagtt
   126541 aggttgaata aagatgcatg gaacttattt gatgagtttt gtgaaaaatt cagagagttt
   126601 aataagtctg atttgatgag catggcatta ttagaataca taaagaagta tgataaataa
   126661 catttttgta ttgttgtaat cattactatt ttagggtaat ataaatataa ctataatata
   126721 aaatggaggt attattatgg tcgataaaat aacaatagat gaagtacttg aatttataaa
   126781 atcaaaaggt tatatatata gtcaagaaat tagaaaagaa ttagataatc tttgtccggt
   126841 ttctgataat gaaatagata agtgtataga agaaaatgat gatgtattca gaaggttggc
   126901 aagtaaatga ttacacttga atatatatgt aaaattaaca aaaagatgat tgaaagatat
   126961 ggtggagctg gaataggtat tagaaataaa aatcttgcta taagtataat tgatggcata
   127021 aaccaggagg tatttggtag agttatgtat cctacagttg aagaaaaaat atctcatatt
   127081 gtagtaggta ttatacaagg acatatattt atagatgcaa ataaaagaac tggattagct
   127141 acattactaa tactttgtga caaatataat atagatgtga attatgataa agaaaattta
   127201 gctatagaaa tagctttaaa taaaataaat gagtctgatt tgagtaatat gttaaaaaag
   127261 tggaataaaa aataaactca ttaaatgtgt tatttgtgtt atgtaaatat aaatctaaga
   127321 atttatttta atataaataa gaatgacgat aaaatcgtag ttttaattta aataacctca
   127381 ttattttgag gttatttttt tattttctat ttaaaacgga gaaggtaaat gttataatat
   127441 atatataatt aaaaaaagga tgtttgaatt tatgaattat aatttaaaaa atgaaaatgt
   127501 attatcagag ctattacaaa atgaggatga aaaaacaagg attggtatac tcaaagttta
   127561 taaagtgtta atattttggt ttgctaaaga aggaaagctt gttgaggaag gaaatgacta
   127621 tattgttgag atagtaggta atgataaaga aaaaattgta aaagatatga accagaataa
   127681 aacatacaat gccataatgg ctataatttt taaaattaat aagatattta aaactttaaa
   127741 ttacgatatt cacttttcta aaccaaaaaa tttagtcgct gaatttgatt tatcaaaata
   127801 tctaacacaa gatgaagtcc ttcaggtatg tagtaagtta actaatgcac aagataagtt
   127861 tataatttat gcagcttttt gtgggcttat tggtaaagat gctgaagact taaggagtat
   127921 aaaaataaaa gacatagatt tagaaaaaag attaataaag ttaaaggata cagagtttaa
   127981 gctggacaag ttcttatttg attttacaaa agatacatta gaacaaaaag agtataaaca
   128041 atatttagag cagggtagta atgctgctga attttatcta tttaattcta attctgaata
   128101 cttaattaaa actaaaccgg atgctagata tggaaatgga ttaaaagaga tgggatattc
   128161 aacaattcgc aaaagattac ttattattaa tgattattta gataataaag tacagttgaa
   128221 tttcactaat ttaaaaattt ctggtattat gcatcaaatg cagctaaatg aaaaaaaata
   128281 tactcaatct ggatattgga ctaataaaag cttgaaagag tttaaggagg ataacaattt
   128341 aaacttcaaa atacaagaag ttctatctat ttataagcaa aaatatatta aggagtaacc
   128401 ttatgagcaa agatgttaaa gagaacataa gtaatgaaca aaaagattta aataaaataa
   128461 atttaatcta tcatattata tatgataatg atagatttaa aatgataaca agaaaatatt
   128521 ttgaaatttt tagattaaag ggtatgtctg ctgaagaaat aagtttaaaa tttgaagaat
   128581 ttctatattc tcttatttca gataagttta aaaagataaa tacagtaaat gatgttaaaa
   128641 aattaagaaa tcaagagaac tcatcatcat taaaacttaa gaagagatgg tctgatatga
   128701 ctttagattc tctaagtgaa gatactaaat cttcaagaaa aaagagcagt aaatacctaa
   128761 aaaaagaatt agagattgtt gaaagtgagt atttaaaaaa tggaagaatc attagtgctg
   128821 gagtaaaaaa tccaaaagaa ttaaaggagc aaagaaaaga ttttttagat gagtggaagt
   128881 caagctctaa ttataacata tgtgattacc catatttaca agagctaagt actagcaaaa
   128941 taaattccgc atttatacat gatatactaa tgtgtataac agaagtacta aaagatgatt
   129001 atgattttga tattaataaa attgcaatca aaactccacc acatatttca cctggaattt
   129061 ttttaccttt cacaaaaggt aaaagatact ctcacttgaa tgttaaaaaa aatgaaaatg
   129121 aatacatgtc agacgactat agtgctaaga atctttcagg taaacaaatg aattttttct
   129181 ataagttttc aattgggcaa gatgaaaata ttgaaaatct taaactagag ctaataaatc
   129241 ctgatacaga aaaaagggct ttgccaaaaa tatatttaga taaacaagac cttgaaatta
   129301 ttagatttgt ttatacttat agccacatga actcattttc attttattta ggcgatttag
   129361 taaagtactt aggactttca gatggaaaaa agaactatat taatatcaaa aatagactct
   129421 taaaattacc ttattatact ttttattcga atcaaactaa tgataaaggc gaattaaagt
   129481 atgagattag ttttaatttg ttctctagta caacaatagt aaatgatgaa aacaataata
   129541 atagagagtt ggttaaaatc acaaaatctt ttattgaaga agtcgaaaga gttaatacag
   129601 atataatgta tagaaatgaa cttgaaaaat tacaattaac acagtcaatt aatctagctt
   129661 atttcttaga gggtagaagg tcttttctta tatcttgtgg tgaggatata aaaaataaaa
   129721 gttttagata tgacatagaa gatttaaaat ttgatgttca tcttaataaa agtaaaacag
   129781 taaaacaaaa tatggagtat ttagaactag gttttaatga gataaaagaa aatcaattta
   129841 taattaaaga ctataaaaga ggaaattctt attttgatgt ttatttctat gaagattttg
   129901 aaaaaagaaa acgtcttata aataatacta tactttcttt acctgactac atgatagaaa
   129961 ataaatctta aaaatggcca tatattctcc gtacttaaca aaaaatgtcg aatttatttt
   130021 aaataaactt aataaaaaaa gtaaaatgac cgtatattct ccgtacttaa caaaaaatag
   130081 atttttcaaa aaaactaaat gaccgtatat cttccgtact taacaaaaaa tagacctttt
   130141 tttaattatt tccttgtcga aaaatttttt ttgtaacata ttttttactt ttcttagtaa
   130201 tttcaaatct cacgtcttct gaaatcacta tgtctgagct aaatgaccgt atcagctccg
   130261 tacttaacag aagacgttga aaccactcta tttgagctaa atgaccgtat cagctccgta
   130321 cttaacaaat atagacataa atttattttt tgggtaagat aaatctgagt aaaaggaatc
   130381 atcaccaaaa tggctatatc agctccgtac ttctgaaatt attgattttt caaaggagaa
   130441 aattatgagt cttaaatata aagataaaga atttgtactt gtagaaaaaa agaatataaa
   130501 tgaattagat aactctaata taaactatat cgacctaaag gacaagcagt attatgtagt
   130561 tacacaaggt agaagaagta agagatttaa taatgaagat gtaagtgaaa taaaaaaaga
   130621 cttagataat ggtatgagtt taagaaaatg tgctgaaaaa tggaattgta gtacaagaac
   130681 catacaagat ataaaacaaa ataagtacta acgaggtatt atttacattt tacctcatta
   130741 atattataat attcttatac tataaaggag ttgattccta tgaaatggtc agaggttaga
   130801 aatttatatc ctaattcatt tgtaaaatta gaaattttgg aatcacatat acaaaatgaa
   130861 aaggagtata tagatgaagt agctcttata aaggtcattc ctaacaataa agaagcttta
   130921 aaagaattca acagatgtaa agataaagaa attgtatata acaccaagaa taaagaattt
   130981 gtaatagata tcataaaaca tattggtata agaagaggtt tgtagtatga aaaatttcaa
   131041 atataaaaat ggattattat atacagatat agaaatctta attgaaaata aaaatatcct
   131101 tgtaaaagat acaatcattg atactggggc atctcacact ataatatcat cttcttattt
   131161 agaagaatca gatattggat ttaatgatga tgatacaatt gtaaaggctt ctggttatgg
   131221 tggaactgtt caatattcag taaggaaatt agttaataag gttgcttgtg gtgacatcac
   131281 tcttgaaaat ataaaattag attttggaga gattgaccca gaagaaaaag taaatggttt
   131341 attaggatta gattttttaa gaaatgctaa tttgattatt gatttagtag ataatctatt
   131401 gataaaaaaa taaaacatgt ttatataagg agttatcaca atatgagtat taaatataaa
   131461 gataaagtag tctttattgt agatagttcg gagaaagaga agctagataa gtcaggaatt
   131521 gcatatgaaa ctttagaaaa tgaaaattat tatgtagtcc aacagggaag aagaagtaaa
   131581 agatttaatg atgaaatgca aaatcaaatt agaaaagaat tagaaaatag tactattagg
   131641 gcaattgcta aaaaatataa gacaagcaca gggataatac aaagtataaa agattttaaa
   131701 tactaatttt gtttcttcat ttacaacaag aaacaaaatt agtataataa gtttatagga
   131761 atattataac ttttaatacc aaggagcgaa ttatgagtat taaatataat aatgaaaaag
   131821 tatttttggt aagtgaaaat gataaagaaa aattagaaaa agctggtata aactttgtga
   131881 gtttagatgg aaattattat gtggtttctc aaggtaagaa acctaaaaag tttacagata
   131941 atgaaataag agaaattaaa aatgatttag acaatggatt gagcataaga aagtgtgctg
   132001 aaagatggga ctgtagtaca aatgtaatca tgaaaataaa gcaaaacact tactaattgt
   132061 gtttttactt aataaaaaca caattatatg ttataatata cctatgagat tatatagggg
   132121 tgattttaga tgttagaaaa tttgataaaa gaatactttt tagattcctt ttgtattgaa
   132181 aatattaata cagatatgaa gaatttagaa ataaaaatag acaatatata taattgctta
   132241 aataatactt taaatgaaaa tcagaggaaa ctattatctc aatttgatga attacttaaa
   132301 atttagaaaa ggaggattaa atatgcaaga attaaaacca gttgctagaa tatcaaaatc
   132361 aaaattaaaa gatatcttag atatttttaa aacttctata agaaaagtag aaaaaataga
   132421 ttattctgct tgtaattctt gtgcaataaa aaataatcct tcttttgata gtaataaatt
   132481 aaatgaattt tgttcaaatt gtcctaaatt aaaaactata tcagagtttt cttatgttgc
   132541 agaaaaagaa acagaattag gtatgataga gattgtaact aatgaaagta aatgtatggc
   132601 tttaagtaaa agtgctataa aacagtattt agcatatcat tttatagtat ctaataaaaa
   132661 ttatgttaga aaagcagtat ccttccaaaa catagccgat atatgcaatg tttctgttgt
   132721 tacagccaga cataaccata atgtattatt acaagttgga ttagtttatt ccacagaaat
   132781 aaaaagaggt aaattcgata tagtcataga tgaagagtat aaaaatcatc ttaaaaaaga
   132841 agatggtgga aaaggttact tgactatgtc attagatact ttaaatcact tattaagttt
   132901 tgaaaatgta aatgaattaa agcttgaaat taaaaagtta atttgggctg atgctaaagg
   132961 aagtaagtta ggtaaaagaa tacgatttaa aaaagataat cttatctcta tacttccaga
   133021 atacataaag aaatcaaaca agcgtataga agccttttta agaagttcta aaactttatt
   133081 tgatgtaagt aatgacacaa tagatacaaa gcgttatgag acgaaagaaa ctatctcaga
   133141 gaaatataca gaaccaatta gaatacaaat atcgaaattc tttgataata ctggttgttc
   133201 tttgagttct aattatagta aagtgttatc tcagataaat ttagatagat ataatttatt
   133261 tgaagaagat ttaagaagta aattagacat ggaaaaagat attattataa atgacttagt
   133321 tggattgtcg gtgcagtatg gagttactag agttttagca gcattagatt atatgtttaa
   133381 taaatataca tttgatgaag aagatataaa ttataatgaa atacgtaatc ctggtgcatt
   133441 tataagaaca ttgattgttc agagcataaa taaaaatgga agtttagcaa tagcaattta
   133501 atatatggag tagttcaaaa aaaatgattt tggctactcc tattagtgtt tgtattcaaa
   133561 ttataaaata cttaaataga gctataaaga gcgtgaaatc tctattagct ctattttttt
   133621 atgcctattt taatgaaatt atatacacaa tagaaagttt tttatacata ttactaattt
   133681 aattttacaa taataatata tatttattca atttattaag aaacttatt
//
LOCUS       DAEOTL010000003        98036 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEOTL010000003 DAEOTL010000000
VERSION     DAEOTL010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 98036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.003"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            158..541
                     /locus_tag="KRH82_000367"
     CDS             158..541
                     /locus_tag="KRH82_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8653669.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            543..893
                     /locus_tag="KRH82_000368"
     CDS             543..893
                     /locus_tag="KRH82_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653670.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(994..1452)
                     /locus_tag="KRH82_000369"
     CDS             complement(994..1452)
                     /locus_tag="KRH82_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653671.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYISGCGLFWSSYWDILEERFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(1497..2285)
                     /locus_tag="KRH82_000370"
     CDS             complement(1497..2285)
                     /locus_tag="KRH82_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8653672.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTTVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(2424..2861)
                     /locus_tag="KRH82_000371"
     CDS             complement(2424..2861)
                     /locus_tag="KRH82_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HBG8653673.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKNCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            3683..4192
                     /locus_tag="KRH82_000372"
     CDS             3683..4192
                     /locus_tag="KRH82_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653674.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            4590..4796
                     /locus_tag="KRH82_000373"
     CDS             4590..4796
                     /locus_tag="KRH82_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase"
                     /protein_id="HBG8653675.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTKLSLCYLTNGAQK"
     gene            complement(5090..5890)
                     /locus_tag="KRH82_000374"
     CDS             complement(5090..5890)
                     /locus_tag="KRH82_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653676.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(6085..7683)
                     /locus_tag="KRH82_000375"
     CDS             complement(6085..7683)
                     /locus_tag="KRH82_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBG8653677.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            8011..8187
                     /locus_tag="KRH82_000376"
     CDS             8011..8187
                     /locus_tag="KRH82_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653678.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            8361..9491
                     /locus_tag="KRH82_000377"
     CDS             8361..9491
                     /locus_tag="KRH82_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBG8653679.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            9732..10082
                     /locus_tag="KRH82_000378"
     CDS             9732..10082
                     /locus_tag="KRH82_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBG8653680.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            10090..10539
                     /locus_tag="KRH82_000379"
     CDS             10090..10539
                     /locus_tag="KRH82_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBG8653681.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            10641..11216
                     /locus_tag="KRH82_000380"
     CDS             10641..11216
                     /locus_tag="KRH82_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBG8653682.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            11209..12618
                     /locus_tag="KRH82_000381"
     CDS             11209..12618
                     /locus_tag="KRH82_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBG8653683.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            12802..14235
                     /gene="eutA"
                     /locus_tag="KRH82_000382"
     CDS             12802..14235
                     /gene="eutA"
                     /locus_tag="KRH82_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBG8653684.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPVVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDETIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            14253..15617
                     /locus_tag="KRH82_000383"
     CDS             14253..15617
                     /locus_tag="KRH82_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBG8653685.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            15630..16511
                     /gene="eutC"
                     /locus_tag="KRH82_000384"
     CDS             15630..16511
                     /gene="eutC"
                     /locus_tag="KRH82_000384"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBG8653686.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            16531..17184
                     /gene="eutL"
                     /locus_tag="KRH82_000385"
     CDS             16531..17184
                     /gene="eutL"
                     /locus_tag="KRH82_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBG8653687.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            17195..17896
                     /locus_tag="KRH82_000386"
     CDS             17195..17896
                     /locus_tag="KRH82_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBG8653688.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            17899..19368
                     /locus_tag="KRH82_000387"
     CDS             17899..19368
                     /locus_tag="KRH82_000387"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBG8653689.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYKTLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            19464..19751
                     /gene="eutM"
                     /locus_tag="KRH82_000388"
     CDS             19464..19751
                     /gene="eutM"
                     /locus_tag="KRH82_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBG8653690.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            19878..20639
                     /locus_tag="KRH82_000389"
     CDS             19878..20639
                     /locus_tag="KRH82_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBG8653691.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            20652..21281
                     /locus_tag="KRH82_000390"
     CDS             20652..21281
                     /locus_tag="KRH82_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBG8653692.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            21323..22048
                     /locus_tag="KRH82_000391"
     CDS             21323..22048
                     /locus_tag="KRH82_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBG8653693.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            22061..22333
                     /locus_tag="KRH82_000392"
     CDS             22061..22333
                     /locus_tag="KRH82_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBG8653694.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            22326..22877
                     /locus_tag="KRH82_000393"
     CDS             22326..22877
                     /locus_tag="KRH82_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBG8653695.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            22889..23980
                     /gene="eutH"
                     /locus_tag="KRH82_000394"
     CDS             22889..23980
                     /gene="eutH"
                     /locus_tag="KRH82_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBG8653696.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            23982..24455
                     /locus_tag="KRH82_000395"
     CDS             23982..24455
                     /locus_tag="KRH82_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBG8653697.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(24575..24676)
                     /locus_tag="KRH82_000396"
                     /pseudo
     CDS             complement(24575..24676)
                     /locus_tag="KRH82_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            24971..25492
                     /locus_tag="KRH82_000397"
     CDS             24971..25492
                     /locus_tag="KRH82_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8653698.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            25871..27046
                     /locus_tag="KRH82_000398"
     CDS             25871..27046
                     /locus_tag="KRH82_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8653699.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            27080..28618
                     /locus_tag="KRH82_000399"
     CDS             27080..28618
                     /locus_tag="KRH82_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBG8653700.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            28650..29852
                     /locus_tag="KRH82_000400"
     CDS             28650..29852
                     /locus_tag="KRH82_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8653701.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDSHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGEGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(30019..30618)
                     /locus_tag="KRH82_000401"
     CDS             complement(30019..30618)
                     /locus_tag="KRH82_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8653702.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            30788..32146
                     /locus_tag="KRH82_000402"
     CDS             30788..32146
                     /locus_tag="KRH82_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653703.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEKLFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            32139..32771
                     /locus_tag="KRH82_000403"
     CDS             32139..32771
                     /locus_tag="KRH82_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBG8653704.1"
                     /translation="MNNKYIRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDIDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            33100..34257
                     /locus_tag="KRH82_000404"
     CDS             33100..34257
                     /locus_tag="KRH82_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8653705.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(34404..35039)
                     /gene="lexA"
                     /locus_tag="KRH82_000405"
     CDS             complement(34404..35039)
                     /gene="lexA"
                     /locus_tag="KRH82_000405"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBG8653706.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(35143..36270)
                     /locus_tag="KRH82_000406"
     CDS             complement(35143..36270)
                     /locus_tag="KRH82_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8653707.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(36591..37436)
                     /locus_tag="KRH82_000407"
     CDS             complement(36591..37436)
                     /locus_tag="KRH82_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653708.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNINLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(37466..37837)
                     /locus_tag="KRH82_000408"
     CDS             complement(37466..37837)
                     /locus_tag="KRH82_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBG8653709.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(37990..38250)
                     /locus_tag="KRH82_000409"
     CDS             complement(37990..38250)
                     /locus_tag="KRH82_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBG8653710.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(38439..39383)
                     /locus_tag="KRH82_000410"
     CDS             complement(38439..39383)
                     /locus_tag="KRH82_000410"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBG8653711.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(39404..40258)
                     /locus_tag="KRH82_000411"
     CDS             complement(39404..40258)
                     /locus_tag="KRH82_000411"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBG8653712.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(40273..41634)
                     /gene="accC"
                     /locus_tag="KRH82_000412"
     CDS             complement(40273..41634)
                     /gene="accC"
                     /locus_tag="KRH82_000412"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBG8653713.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(41650..42102)
                     /gene="accB"
                     /locus_tag="KRH82_000413"
     CDS             complement(41650..42102)
                     /gene="accB"
                     /locus_tag="KRH82_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBG8653714.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(42372..42818)
                     /locus_tag="KRH82_000414"
     CDS             complement(42372..42818)
                     /locus_tag="KRH82_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653715.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            43093..43371
                     /locus_tag="KRH82_000415"
     CDS             43093..43371
                     /locus_tag="KRH82_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653716.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     VLVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(43500..44246)
                     /locus_tag="KRH82_000416"
     CDS             complement(43500..44246)
                     /locus_tag="KRH82_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653717.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(44375..45019)
                     /gene="trmB"
                     /locus_tag="KRH82_000417"
     CDS             complement(44375..45019)
                     /gene="trmB"
                     /locus_tag="KRH82_000417"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBG8653718.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(45157..45477)
                     /locus_tag="KRH82_000418"
     CDS             complement(45157..45477)
                     /locus_tag="KRH82_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBG8653719.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(45930..46178)
                     /locus_tag="KRH82_000419"
     CDS             complement(45930..46178)
                     /locus_tag="KRH82_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8653720.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVNDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(46209..46670)
                     /locus_tag="KRH82_000420"
     CDS             complement(46209..46670)
                     /locus_tag="KRH82_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBG8653721.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQL"
     gene            complement(46708..47541)
                     /locus_tag="KRH82_000421"
     CDS             complement(46708..47541)
                     /locus_tag="KRH82_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653722.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(47815..48501)
                     /locus_tag="KRH82_000422"
     CDS             complement(47815..48501)
                     /locus_tag="KRH82_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653723.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(48516..50993)
                     /locus_tag="KRH82_000423"
     CDS             complement(48516..50993)
                     /locus_tag="KRH82_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8653724.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRILIESEEEITENL
                     VNKLSKELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSDK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(51212..52615)
                     /locus_tag="KRH82_000424"
     CDS             complement(51212..52615)
                     /locus_tag="KRH82_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8653725.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLKKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIIFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVHKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            53109..53969
                     /locus_tag="KRH82_000425"
     CDS             53109..53969
                     /locus_tag="KRH82_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8653726.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(54208..54765)
                     /locus_tag="KRH82_000426"
     CDS             complement(54208..54765)
                     /locus_tag="KRH82_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8653727.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(54955..55842)
                     /locus_tag="KRH82_000427"
     CDS             complement(54955..55842)
                     /locus_tag="KRH82_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8653728.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            55961..57160
                     /locus_tag="KRH82_000428"
     CDS             55961..57160
                     /locus_tag="KRH82_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBG8653729.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(57354..59909)
                     /locus_tag="KRH82_000429"
     CDS             complement(57354..59909)
                     /locus_tag="KRH82_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8653730.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(59906..60592)
                     /locus_tag="KRH82_000430"
     CDS             complement(59906..60592)
                     /locus_tag="KRH82_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653731.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     IVVNTGGEVL"
     gene            complement(60669..61577)
                     /locus_tag="KRH82_000431"
     CDS             complement(60669..61577)
                     /locus_tag="KRH82_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8653732.1"
                     /translation="MFILAFIICTVVIFIVSTKINQRRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(61579..62250)
                     /locus_tag="KRH82_000432"
     CDS             complement(61579..62250)
                     /locus_tag="KRH82_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8653733.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            62512..63576
                     /locus_tag="KRH82_000433"
     CDS             62512..63576
                     /locus_tag="KRH82_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBG8653734.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            63734..64420
                     /locus_tag="KRH82_000434"
     CDS             63734..64420
                     /locus_tag="KRH82_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8653735.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKVKAFLNHLTVKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            64410..65441
                     /locus_tag="KRH82_000435"
     CDS             64410..65441
                     /locus_tag="KRH82_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8653736.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALTIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTNSNGKIHVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            65523..66188
                     /locus_tag="KRH82_000436"
     CDS             65523..66188
                     /locus_tag="KRH82_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653737.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            66201..68618
                     /locus_tag="KRH82_000437"
     CDS             66201..68618
                     /locus_tag="KRH82_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653738.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(68799..69590)
                     /locus_tag="KRH82_000438"
     CDS             complement(68799..69590)
                     /locus_tag="KRH82_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8653739.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(69623..70210)
                     /locus_tag="KRH82_000439"
     CDS             complement(69623..70210)
                     /locus_tag="KRH82_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8653740.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIYNEKKARLFSESIGIDLECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(70387..71778)
                     /locus_tag="KRH82_000440"
     CDS             complement(70387..71778)
                     /locus_tag="KRH82_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBG8653741.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(71968..73266)
                     /locus_tag="KRH82_000441"
     CDS             complement(71968..73266)
                     /locus_tag="KRH82_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBG8653742.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIQNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(73625..74500)
                     /locus_tag="KRH82_000442"
     CDS             complement(73625..74500)
                     /locus_tag="KRH82_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBG8653743.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(74693..75379)
                     /locus_tag="KRH82_000443"
     CDS             complement(74693..75379)
                     /locus_tag="KRH82_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBG8653744.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(75428..75961)
                     /locus_tag="KRH82_000444"
     CDS             complement(75428..75961)
                     /locus_tag="KRH82_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBG8653745.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(76005..76637)
                     /locus_tag="KRH82_000445"
     CDS             complement(76005..76637)
                     /locus_tag="KRH82_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBG8653746.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLETVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(76727..77806)
                     /locus_tag="KRH82_000446"
     CDS             complement(76727..77806)
                     /locus_tag="KRH82_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBG8653747.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(77939..79285)
                     /gene="pepV"
                     /locus_tag="KRH82_000447"
     CDS             complement(77939..79285)
                     /gene="pepV"
                     /locus_tag="KRH82_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBG8653748.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTIAAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(79354..80634)
                     /locus_tag="KRH82_000448"
     CDS             complement(79354..80634)
                     /locus_tag="KRH82_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBG8653749.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(80761..81021)
                     /gene="hfq"
                     /locus_tag="KRH82_000449"
     CDS             complement(80761..81021)
                     /gene="hfq"
                     /locus_tag="KRH82_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBG8653750.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(81135..82070)
                     /gene="miaA"
                     /locus_tag="KRH82_000450"
     CDS             complement(81135..82070)
                     /gene="miaA"
                     /locus_tag="KRH82_000450"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBG8653751.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(82108..84075)
                     /gene="mutL"
                     /locus_tag="KRH82_000451"
     CDS             complement(82108..84075)
                     /gene="mutL"
                     /locus_tag="KRH82_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBG8653752.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKKSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYSCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(84086..86929)
                     /gene="mutS"
                     /locus_tag="KRH82_000452"
     CDS             complement(84086..86929)
                     /gene="mutS"
                     /locus_tag="KRH82_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBG8653753.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(87090..87824)
                     /locus_tag="KRH82_000453"
     CDS             complement(87090..87824)
                     /locus_tag="KRH82_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653754.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIKVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(87793..88806)
                     /locus_tag="KRH82_000454"
     CDS             complement(87793..88806)
                     /locus_tag="KRH82_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8653755.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(88828..89598)
                     /locus_tag="KRH82_000455"
     CDS             complement(88828..89598)
                     /locus_tag="KRH82_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653756.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(89573..89863)
                     /locus_tag="KRH82_000456"
     CDS             complement(89573..89863)
                     /locus_tag="KRH82_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBG8653757.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(89994..90093)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      90713..90802
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            90855..91031
                     /locus_tag="KRH82_000457"
     CDS             90855..91031
                     /locus_tag="KRH82_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653758.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(91146..91502)
                     /locus_tag="KRH82_000458"
                     /pseudo
     CDS             complement(91146..91502)
                     /locus_tag="KRH82_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            91758..92672
                     /locus_tag="KRH82_000459"
     CDS             91758..92672
                     /locus_tag="KRH82_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HBG8653759.1"
                     /translation="MNKKFRLYQVDSFTKEKFTGNPAGVITNADGLSESQMQKIAREL
                     NNSETAFIFNNLAKNHQENYDVHIRFFTPTNEVPICGHATIAAHYVRAVENQFNNKTV
                     FQKTGAGILPVDIIKKDNDYEIIMTQGKIEVPPPLQQTYQKRLLNAFGILKKDIRTDC
                     PIAISSTGHSKVMIGIKELSTLNSLSPNLYELSKISQEIKCNGHYIFTLHNKETLQVH
                     GRMFAPAIGISEDPVTGNANGPLGAYLVHYKVIPTPNTEFIFEAVQGEAIKRKGKMLV
                     KVIILDNKPVEVKIIGKAVIAFSTNIEI"
     gene            92903..93514
                     /locus_tag="KRH82_000460"
     CDS             92903..93514
                     /locus_tag="KRH82_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBG8653760.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            93812..94150
                     /locus_tag="KRH82_000461"
     CDS             93812..94150
                     /locus_tag="KRH82_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBG8653761.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSNKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(94557..95993)
                     /gene="miaB"
                     /locus_tag="KRH82_000462"
     CDS             complement(94557..95993)
                     /gene="miaB"
                     /locus_tag="KRH82_000462"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBG8653762.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
     gene            complement(96241..97677)
                     /locus_tag="KRH82_000463"
     CDS             complement(96241..97677)
                     /locus_tag="KRH82_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBG8653763.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT        35192 a        14204 c        12929 g        35711 t
ORIGIN      
        1 atatatagaa aatccttata aaaatttaaa ttgtaatgaa taggaagtaa ttaaaaagaa
       61 tttttattga tttttaaaaa tttagttaga aactatatca ttatggtaaa aaatgtatta
      121 taatgtttag aaatattata ataaggagcg attaaacatg aatctatcga agaaaataga
      181 agataaaaga aaagctaaac agagagctga aaaagttaag aaagctaaaa ttgctacagc
      241 tggtgtggta ttaggagctg ttactggtgc agtgagtgga gtacttttgg ctcctaaatc
      301 tggaaaagaa acaagagagg atataaaaga tgcttcacaa caaattgctg aaaagataaa
      361 tatgaaaact gtagacgtaa aaggcaaagt atctgagaag ctagaggata aaaaaggaaa
      421 ctttatagaa tcaaagaaaa aaataaaaaa atatatagat aacaaaaaga gtgttgaaaa
      481 ttctagtgag gaagataaaa taatagatat agttgaacca gttagtgtta ctgaggaata
      541 atatggacaa tacaataacg attaacataa gtataatata tgtattatta gctatacttg
      601 cttgtattgc tttagtttat ttaattattg tacttgttaa actacataag attttaaata
      661 atgttggaac tatgttaaat gaaaatactc aaaatataaa tacaacttta aataatcttc
      721 ctaatgttgt agaaactttt ggagaagtag gagaaaatat gaaagatgta acagaagtag
      781 ttactgaagt tacagcagat tttcttgtta ctaaagacag tgtcaaatca aatatggatg
      841 ttatagttga tatattgact ataattaaaa acatttttct agataaaaaa taataagtta
      901 atataaaata agcctataag atataattta aacgacctta aaatagcatt tataaggtcg
      961 ttttttatta gcttgatttg acactatgtg tttttaataa ttggtaatat tcctctttat
     1021 catttgaaca tatatatcta tgcttgttgt ttcaattaca tccataagaa catctttaca
     1081 ttcaagctca aaatcttcca ttccttctaa atattcatca tcttcatcaa aaaagatata
     1141 agaattatat agccattctt caaatctttc ttcaagtata tcccaatacg aactccaaaa
     1201 taatccacaa cctgatatat aagatgctct actttgattt atataaacct catttagaag
     1261 cttttgtaat ctactgctat aaagaaaatc tgctcttcca ctgcttgata ttaattcatt
     1321 taaatcttct attgacatta attcaacttt accactttta tcataaggag tataattttc
     1381 atcaacccat ttatgtggtt tgttttctct gcatactgtt gctatcaact ctacaacttt
     1441 tgttcttatc atttttttat cctaacttgt ttatttttta taaaataatc atgattttat
     1501 aatttatcta tttcttgtaa tgctaattta acagtttcat atctatcagc accatttatt
     1561 actacatcac cttttacaag tttattagct tctccaccta caacataaac ctttttacct
     1621 aaaccttgct tataactaga cgcctcaatt attaaagaat ctttcaattg ccaatgtaaa
     1681 atctgagcag ccactttatc agcatcacct gtataaacga ttacattttc atacacttta
     1741 ttttcccctc ccccttgaga atttgatata gatttgttta gtataccttc tgctatcaat
     1801 ttagcaactt tatctttatt attaacataa taatctgtat ctgctttact atctacaaaa
     1861 catacttcta ttaatattgc tggtgcaata gtatgattaa gccaataaag acctctaaca
     1921 tcagactttg cacccctatc tttgaatact gtagctaacc tagtattcac tctttctgca
     1981 taggttttgc cattattagt cttatatatt gtttctgtcc ctactgtagt tgaagttgta
     2041 gcatttgaat taaaatgaat ctgaacagcc aaatcagttt cctgtttatt tgctatagca
     2101 cattggtctg ctaaatgatt acttgattca tcaactcttc ctgtataaac agtagctcca
     2161 cctattttaa gccatttaac aattaagtca ttcagtattc ttgtttcttt gctttcgttt
     2221 atatacccaa cagctcctgt accttttcca attaaagtgt gccctggtat tattactact
     2281 ttcaaactaa catctccttt acaattaaat ttaacttcta tttaatatat gcataaccta
     2341 gaattttgtt tctttttata tcttatactt ttattataac ccattttgta aaaatataga
     2401 atattaagta aataatgtta aaattataat tttgtatata agacattact tgattgcaat
     2461 aattttatag catattcatc tattctatat ccagttctat aatatatatg tttaattcca
     2521 gcttgaatta tagccttagt acaatttaag caaggaaagt gagttacata aatagagcaa
     2581 tttttaactg aaataccttc ttttgcacaa taataaaggg cattttgttc agcgtgaatg
     2641 gttctaatac aatgtccatc tctcatttca tgaccaactt cactacaatg cttatctcca
     2701 gaaatactac cattatatcc agtagacact attctgtttt ctgaattgac aattatagct
     2761 cctacataag ctctatcaca agttcctctt tcagctactg tttcgcacag tctcataaaa
     2821 tattcttgcc atgagcatct attttcaagt tttttattca aatcatatac ctccaaaatt
     2881 tatatctaat atataagatt tataccttaa aaataatatt aaaaacaaat ttatacgata
     2941 aataaaattt attaatactg tttttagtct aaattatttc attttaaatt aaagttacaa
     3001 ggaatctaaa attatatata tctttcttcg taatatgaat gttacaatat aaaaaactgt
     3061 ctcaataaaa tagagacagt tttacagtca aagtttataa tacaagttca tatttttctt
     3121 taaattcttt tacagcttcg ggccatgcct tttgttctgt aatacctttt tctttagcta
     3181 ttttaattgc aatctctctt atcattgcag cgccttctaa tattcccatt tttaatctcc
     3241 cttcaaatat ctttttgtat agaatataaa tagtgctaag atttattaca tgctgcatat
     3301 acaatatcta tacaacacat aacttgtaaa ttccttttat tttcatacgt ctttaaccga
     3361 catataatta tattcaataa gttttaaaat tatgaactca attataatta tttttatttt
     3421 tttagaatct aaacactaaa aattgtaggt aaatttgtct tatgccttta taaatatttc
     3481 tacagtttta attactggac atatctattt ttattataaa aagcgcttaa aaatcgagaa
     3541 tatccgcata aaaactatat ataagcaaaa cgattaaagg aaaaagaaga aatttacttg
     3601 aatgttaaaa tgcgttgctt gaagcaatgg gcagttttgc ttataatatc ggtaacaact
     3661 gaaagaaagg tggttagccc taatgttaag cgaaaacatt aaaacaatca ggaagtcaaa
     3721 aggactttca caacaagaac ttgctataaa actgaatgta gtgcgacaaa caatatctaa
     3781 atgggaacaa ggactgtcgg ttcccgattc tgatatgttg atttccatat cagaggtgct
     3841 tgaaacgccc gtaagcactt tacttggaga aactattgtt gagtcggaag ttgataactt
     3901 aaaagtgatt tctgaaaaat tagagattat aaacttgcaa cttgcacaaa gaaaaaacat
     3961 gagaagaaaa atgtttcatt ggttatttat tttattatgt gcagtcatat taatagtttt
     4021 tgtggtctta gggagactaa atagtcctta cttggattgg aattataccg accctgaaac
     4081 cgctgttttt ggagtagctt ttcatgcttt tgagtggcta tttgtcagat tagtaccgat
     4141 tgtccttata ggagcaatta ttggaatctt tttgacacgt aagaaaatat gaagtaactc
     4201 tgctttttat aatacagcaa gcgttcctta aaagcgtcat tctacatggc aatcgaggac
     4261 gactatgtaa tgaagaacct ttttgatttc caactaagcg aagttattga ggacgacagt
     4321 aggcccaaaa ccgcattaag taaagtacag gaagcaagac tgctggactt atactctcat
     4381 gcgtcagatg caggaaatgc gaggtctggt agcatgattt acaacgattt gtacaactat
     4441 tgcgagtaga aatatatgga gataagtatt atctacaaag tcagaaaaga aatgatttga
     4501 taatttaccc atgttataat tattgatgtg aaatcaataa atcaaaattc ctttttggga
     4561 tttaacaata aggaaaaagt gaatgacttt tgcaaggagg tgttaatatc agacaagtaa
     4621 agtcttttgt ttttccagtt atatccttaa tattcttaga ccaaattagc aaagttctta
     4681 taggattatt cttaatggac tttgaaattg atataattgg gaaattttta agattcaatc
     4741 ctgttcaaaa tacaaaatta agtctctgct atctaacaaa cggagcacaa aaataaaaat
     4801 taaatataaa gcacagttaa ttttgattaa aaagttgact gtcttttctt ttgtagaaat
     4861 ttaagcatag gtaataaaga aatgactgca tttaagcatt atgtatataa ttggaggcaa
     4921 taaaaagcca gcaaagccca taaaatagag ctgtgctagc aacatgatga attataagaa
     4981 gataatcaaa aacttacgct ttattttaat ttaaaaaaat gattactgta aagaaatcat
     5041 tttttattat aatcactgat acatcaaata ttctaaataa aatttttatt tatctggaat
     5101 tgtatatttt ttctataata ttaactacag cgtacattgc ccaagcacag atagccaata
     5161 caaatactcc catcattact aaatctaatt taaatacttg agaaccatat actatcaagt
     5221 agcctattcc atatcttgaa actaaaaatt ctccaactat tacacctacc catgccatac
     5281 caatattaat tttagttaaa tttattaaat ttcctgtgtt tgcaggtaat atgagtttaa
     5341 ataatatttg agatttagta gctccaaaac tttttaacat cttaattttt tcttcatcta
     5401 tattcataaa ataattataa gctgaaagta tagtaacaac aacagaaatc gttacagctg
     5461 ttacgacgat tccttctatt ccagcaccta cccaaactat aattatagga gctaaagcag
     5521 tcttaggaag agcatttaaa actaccaaaa atgggtctaa tatttttgat aatttttctg
     5581 accaccaaag agcaattgct accaaaatac ctaatacagt acctataaca agaccaagaa
     5641 cagtttcata tacagatatt ccaatatgtt taaataattg accactaaat gcatattgaa
     5701 taaataaatt gtaaatatca cttggtttgc taaatagaaa tgtatttata acatttaagt
     5761 cagctaaaag ttcccagatt acaataaaac caattaaaat taatagctgg tagaataata
     5821 catttctttt ttctcttttt acacctttaa catagtttat atatccttca gatcttttat
     5881 taagcctcat gtgtatctag ctccttccat aatatgtcga aatacttttg aaaatcagga
     5941 actttacgtg ttttgagagg cgtttttgtt ccatccatgt taagttcaat atcgtaaata
     6001 ttttttatgg tagctggtct tttagatagt attgcaacct tatctgatat gcttattgct
     6061 tctgctatag ctaaaaaagt gcaactaatt gcttaaagaa acagaattat caacttcagc
     6121 acccatataa acaatattaa gatttcctaa actgctatcc caaacgatac tattaataat
     6181 agtagataat aacaatctct tatcatctaa actggcatta tcaacttcat cattaaatct
     6241 cttcaaatta ctaacaataa tatcaatatt aatactgtca ctactaatat tgatgttact
     6301 agattccaaa atattaatct tatcctttaa aatactaatc tcattattta ggctctcaat
     6361 ctgggaaact atataatcag aagcagtact accagtattt tttgcaagct ctataactaa
     6421 atttttaata agtctttcct tatctaaaat ttgattttta agtaaattag tctcagattt
     6481 aaaaatatta aaaacattat cagtcttaat gttattacta ttgaatgcac ttataataga
     6541 ctcttcttta caattcttaa ttttatctat aactaaactt tcaactaatg gaccattaag
     6601 atttttacag ttgcaactat cagacccaag tgttttttta gtaccacaaa tataataata
     6661 ctttaaatcc ttgtcagttt ttttgccttt ataggtaatt ctcatattag aaccacattt
     6721 accacatttt ataagaccag ataaaagagc agtttttcca gttgatatcc ttggagtttt
     6781 atcacgattt ttatctaatt gattttgtac ttcaagccat atttcaggtt ctatgactcc
     6841 atggtgtttt gcaattgctg ctattgagtt agatgtattt ttagcatagg taaggattcc
     6901 acattttcta tctggagtac ctacaacatc cataccacta tttttaaggt aatctaaaat
     6961 ttcatcatta gcttttacat atgctggatt tctaagtatt ctagataaag aactagggtc
     7021 aaatttgcca ccacgaggac cccttattcc attattatag acatatttat ataacttaga
     7081 taaggaccta agttctaaat atttattgta tattagcttt acaatctcca tttgttcatc
     7141 atttacttga agcttataca tacttctttc ttttagattt tcatctaaga atgtgatttt
     7201 ttcactgttg aatccatgag gtgtattgcc tccaagccat ctaccactac gggctaattc
     7261 atacatattg tcttttatac gttctgctat tgtttctctt tctaattgag caaatacact
     7321 tgatataaac atcatagctc ttcccattgg agttgaagta tcaaattgtt ctttgataga
     7381 tataaatgat atgtttagtt catttaattt ttctattaaa gtagagaagt cagatacatt
     7441 tctcgatatc ctatctaatc tataacaaac taggtaacta aatttcttat ctttggcatc
     7501 ctgcatcatt ttcttaaatt gtggtctatc tatattgcta ccactaaatc cctcatcttc
     7561 atatatcaaa aaatctttta caccaataga ctttgcataa tcaatacata attgtatttg
     7621 attttctata gaatcacctt ttccagtaaa tcttgatttt cttgaataaa ttgcagcttt
     7681 caaaattaaa acctcctata agttaggata tatatttgaa actatttatc tacaaccttt
     7741 taagtaaact tattagaatg aatttattaa ttaggtaaat ttatataatt ctacttttta
     7801 taatatatga ctatttattt tatttcttta ctattcaagt tctaaatcaa taataaattt
     7861 tgatatttaa ttgtatcagg acaaatctct aatttcatag attattaata taaaatcata
     7921 ggttagtgtg aaaaagttga aatttaaata ttttaaaaga taattttttt gaactaatag
     7981 gtataacaaa aatttatagg gggattgcat atggaaatca atgttataga aattttccct
     8041 aaagataaag ctaaacttaa taaaatagaa atggataaag ctagttggtt tgtaaatata
     8101 ataagtaaaa aatatcctaa agaagcttta aatgaagcat ttagtacttt agaaaaagaa
     8161 ttaaatataa gtaaagctaa tacataagct ttaattattg attttatata ctattggttt
     8221 tatacactat gacttgacat tatattaatc aaatagtata tttttaaata tagcacaatg
     8281 aagtgttaaa agagcaatgg agctccatag ataaagtcta tggagctttt ttgcgtattt
     8341 aacttaagga ggataggact ttgaataact ttgagattaa aactagaata aaatttggag
     8401 aaggctcact aaaagctttg caagaattaa aaaacaaaaa tgtactaata ataacagacc
     8461 cttttatggt gaaatcaaaa acaatagata aaataacatc taatttaata aactcaacat
     8521 atcaagtttt tgaagaaata gtaccagacc caccaataga agtagtagta gcaggaatag
     8581 aagcatttaa atctataaat ccagacgtaa taatagcatt aggtggtggt tctgcaatag
     8641 atgcagcaaa atctataatg gacttttcta aaaaaatatt aaaaattaac gaagtagagt
     8701 ttatagcaat accaacaaca agtggaacag gttcagaagt aacatcattt gctgtaataa
     8761 cagatagtca aaaaaaatgt aagtatccat tagtgagtga tgatttactt ccagatatgg
     8821 caatactaga cccagagctt gtaaaaactg taccaaattt tataacagca gatacaggga
     8881 tggatgtatt gacacatgct atagaagctt acgtatctac aaattctaat gacttttcag
     8941 atgcactagc tgaaaaagct ataaagttag tatttaaata cttaataaaa gcatataaag
     9001 atggaaatga catagaagct cgagaaaaaa tgcacaatgc atcttgttta gcaggtatgg
     9061 catttaacca agcatcactt ggcataaatc attctattgc acatgtatta ggtggaaaat
     9121 tccatatacc acatggaaga acaaactcta tattacttcc tcatgtaata gaatataatt
     9181 catcaatagt aggatatact aacacaactt actctgctac agctaaaaaa tatgcacaaa
     9241 tagcagaatt agtaggactt gggagtgcta atataagaat atctgttaga aatttagtaa
     9301 atgaaataaa gaaactacaa aaagaaatga atatgccaac taaattgaca caatgcaaat
     9361 taagtttaga agatataact aatgaagaaa gagaaatagc aaaacttgct ataaaagata
     9421 cttgtacatt aactaatcct aaggtaccaa ctgaagatga tataataaac atattaaaga
     9481 acattaaata actacatttt attacatgta aatataatat tatacaaata gggaaaatgt
     9541 ttttaaaaat ataaattata tattgacaaa tataaaacat aaaactataa tgaaagtatc
     9601 acaaaggcgt gatactttag tagaaagcaa tggagcttct taggaatatt aatattattc
     9661 ttatggagct ccttttattt taatcaaata gctttttaat aaactatatt caaagaaagc
     9721 agggaataaa tttgactgaa gaatctaagc aaagagttat tcaagaatat gttcctggaa
     9781 aacaggttac attagcacat atcatagcta accctaatga agacatatat aagaagttag
     9841 gattagtact tgataaaaaa gatgcaatag gaatacttac aataacacca agtgaagcgt
     9901 caataatagc agcagatgtt gctacaaagg cttcaaatgt atctttaggt tttatagata
     9961 gatttagtgg ttcagtagta atatcaggtg atgtaagttc tgtagaatca gcgttaaatg
    10021 atgttttaga agtcttagga aatatgttaa acttctcatc tacaaaaatc acaaggacat
    10081 aataatacaa tgaagaatat aatatttatg ggaaagacag gtagtggtaa aactacctta
    10141 tgtcaaaaac tagaccagtt agaattaaag tataaaaaaa ctcaatcagt ggaactttat
    10201 aataatgcaa tagacactcc tggtgagtat atggaaaata gaaacctata taatgcctta
    10261 ataacaacat cagcagatgc taaaattata gcaatagtgt atgatgccac acaagaagaa
    10321 aattatatag caccaggttt tgccagtatg ttttgcaaag acgtaatagg aattataact
    10381 aaaataaata aagctactga aaacgaagtc aatatagctt atgaaagact atcactagca
    10441 ggagcaagtc aaatctttaa aatagacaca gttgataata ttggacttga aaaattattt
    10501 aaatatctag aaaaatataa aaatatagat gaagtttaag gggaaatatt tttttattca
    10561 aaaatattat taaagtatga taaaataaaa aaatgtataa actattttaa gaagatttaa
    10621 tctttaagcg aggtaggaac atggggaaaa aaatactatt ggttgatgat gaaccactgt
    10681 taaggatgga tacaaaagat atattagaaa gtcatggcta tgaaataata ggcgaagcaa
    10741 gtgatggatt tgaagctgtt gaaatgtgta aaaaacacaa acctgattta gttataatgg
    10801 atatagagat gccaatactt gatggtataa aggcaggcaa aataatatgt aaagaaaatc
    10861 tagctggtgg agtactttta ttaacttcat ttgaagataa agaatacgta gaaaaagcta
    10921 aaagtatagg tgcttatgga tatttagtaa aaacagcaag tgaaaaatca cttatcccaa
    10981 ccatagaaat gtgtttaaat aaggtaaatg aatttgaaaa aatgaaaaaa gatttagaaa
    11041 aagtaaattc taaattgaat gaaagaaaat tagtagaaag agcaaaaggt atacttataa
    11101 gagagtttaa gatttctgag gatgaagcat acactagaat aagaaaatta agtatggata
    11161 aaagaactac aatgatggaa attgccaaaa tgattataat aggatacgat gactaatacg
    11221 ataaaaaaaa tatcaactgc acaaacatac ttaaataata acgaaattga aaaaattata
    11281 gaagtatcaa aatccttaga tttaatggct tctttttatg aagctgatgt ttttatagat
    11341 gtactaagta aatttgatga tgaagcaatt gttgtggcac atggtagacc taaagaaaag
    11401 tcaatgtact gtgaaaatgt tataggtaaa aaggctttaa ttgaaaatga accaggagtt
    11461 ataaagtgct taaaaacagg agaaagagta agagatatta aagctttaac acaggaatat
    11521 aaactggtca aacaaaatat tcagccaata acactagatg acaaagtttt agcagtacta
    11581 atagttgaaa aagatataag tagtgaagtt aagaatgagt ttaatgctag tgaagacgaa
    11641 gaaaataaaa atttacatca gtttataaaa cttatcggaa ataatgactt tttagttgat
    11701 aatttaaatt cagccatatt aatatttgat aaaaatggaa aattaaaaat taaaaatcgt
    11761 attgcaactg agatatacaa aaatcttggg tttggatatg atatacaaga tatgcattac
    11821 aatgatttag atatagaaac caacaccttt gaaaatatat taatggatga aaattatgat
    11881 gagacaaatg aagtttcaat aggtaatatg ttttttaaaa taaagaccat atacatcaaa
    11941 gatgatgaat ttaaggtttg caaaatagta caagatataa gtgatttaaa gagaaaagaa
    12001 gaagaattag ttttgaaaac agtggctata agagaagctc atcatagagt aaaaaataat
    12061 cttcatacag taatatctat aataaaaaaa caaagtagat tatctcaaaa tgatgaagta
    12121 aagcagtgtt tagataacat aataaatagg gtatttgcaa tactttcgac tcattattta
    12181 ctatctaaag aagttgataa taatatatct atacgagaag gtatcaattt attagtgtca
    12241 aatattcaag gtggctattt atttagtaag gatatagata tacgtataac tggtgaagat
    12301 tttaaaatta gtggagaaaa agcaacagca atacttttgg ttataaatga aatactacaa
    12361 aattgttatg accatgcatt ttcggataga gaacatggta ctatacaaat attaataaat
    12421 aaagataacg actatagaaa tattgctatt atagatgatg gaattggatt tgatagtaat
    12481 aatataaata aaaatagctt agggacatat ataatagata gttatataac acagatgtta
    12541 aaaggaaata tagagagaaa aagtagtgag aatggtacag aagtattaat tactatacct
    12601 acacaaatta atatttaaat aataactcat ctacaaagta gtagttttaa ttgagcaaag
    12661 aggcttaagg ttattaatag attaagttaa ttgaatgtat ttataaaaat tataagtata
    12721 tattcaattt aacaggtatt tattataact ttaagcctct ttgcttgttt aagacatact
    12781 taaattttag gaggtgagaa aatgagagaa gagttattaa gtgttggtat tgacattgga
    12841 acaagtacta ctcagttaat tttttctaaa ttaatagtag aaaatactga atcaaatttt
    12901 tcggtaccta gaataagtat agtagacaaa gaaattattt ataaaagcaa agtttatttc
    12961 acccctctta tttcaaataa tgaaataaat ggtcaacaaa taaaagatat agttgaaaat
    13021 gaatataaaa aagcaaatat atctaaagaa gatatacata caggagcagt aataataact
    13081 ggtgaaacag ctagaaaaga aaatgcaaat gatgtacttc atactttgag tggatttgct
    13141 ggggacttcg ttgttgcaac agcaggacct gatttagaaa gtataatatc aggaaaagga
    13201 gctggagctc atatttattc aaaagaacat tcaactacaa ttgtaaatat agacataggt
    13261 gggggaacta gtaacatagc ctcatttaaa aggggagaag taaccgatac tgggtgtttg
    13321 gatataggtg gaaggcttgt aaagatagat aaaataagta aaaaaataac ttatatatca
    13381 cctaaaatag ataaaatcat aaaagataat aatttaaatc ttcaagtagg cacaatggct
    13441 actgtagaaa atacaaagcc agtagtggat ataatggttg acttattaat ggaaagcata
    13501 ggactaaaga aacagacacc tttgtttgat tttataataa ccaataaatc aataagtata
    13561 gatgaaacta ttaaaaatgt ttcattctct ggtggagtag ctgattatat ttactatgat
    13621 ggagaaataa aagattattt tgaatatggt gacttgggaa ttttacttgg gcaagcaata
    13681 aaaaattgtg aataccttaa aaaagtaaat gtagttaaat ctatggaaac aataagagcc
    13741 acagtggttg gagcaggttc tcatactact gaagtaagtg gaagtacaat aacttacact
    13801 agcgaaaagt ttccacttaa gaacttgcca gttttaaaat tatcaattga tgaagaaaca
    13861 ggcacttcaa aacaaatcag tgaagctata aaaaataaac ttaattggtt taaactagaa
    13921 aatgatttac agaaagttgc tatagccatg ataggaaaga aaaatccaac ctttttagat
    13981 atacaagagt atgctaaagg gtttgtagat ggaatgcaac aaatcataga aaatgattta
    14041 ccttttatag taattgttga aaatgatatg gcaaaagtgt taggtcaagc aatatatgca
    14101 ttattaaatt atgaaaaaga aattgtttgt atagacagtg tcaaggttga aaatggagac
    14161 tatatcgaca ttggaaaacc tatagttgaa ggtaaagttt tacctgtggt aataaaaaca
    14221 ttagttttta attaatagaa ggaggtaagt aaatgatttt aaatacaaaa ttatttggac
    14281 gtacttatca gtttaaaggc ttatatgatg taatggctaa agctaatgaa gaaaaatcag
    14341 gagataaatt agcaggtctt gcagcagaat cagctgaaga aagaatagca gcaaaagttg
    14401 ttttatcaca cataaaattg gaggatataa gaaataatcc tgcagtggca tatgaagaag
    14461 atgaagtaac aagaataata caagatgctg taaatgaaaa agtttatgaa gaaataaaaa
    14521 attggacagt ctctgaactt agagaatggc tattggattc aaatactaca agtcttgata
    14581 taagaagaat atcaagagga ttaacttctg aaatgatagc agcagttgca aaattaatgt
    14641 caaatatgga cttagtttat gcagctaaaa agataaaggt tactgctcac tgtaatacaa
    14701 ctataggaga acaaggaaca ttatcagcaa gacttcaacc taatcatcca acagacgacc
    14761 cagatggaat acttgcatca cttcttgaag gtttaacttt tggtatagga gatgcagtac
    14821 ttggattaaa tccagttgat gactctgttg agagtgttac taaagtatta aaaagatttg
    14881 aagaagtaaa acaaaaatat caaataccaa ctcaaacatg tgtattggca cacgttacta
    14941 cacaaatgga agcaataaga aatggtgctc ctgcagattt aatattccaa tctatagcag
    15001 gttctgaaaa aggaaatgaa gcatttggat ttaacggcga cactatagaa gaagctagac
    15061 agttagcctt aaaacacggt acagctacag gacctaacgt tatgtatttt gaaactggac
    15121 aaggttcaga attatcttca gaagcacatc atggaataga ccaagttact atggaagcta
    15181 gatgctatgg atttgctaaa aagtatgaac cattcttagt aaatacagtt gttgggttta
    15241 taggacctga gtacttatat gatgctagag aagttgtaag agcaggactt gaagaccact
    15301 ttatgggtaa actacatggc ttaccaatgg gtgttgatgt ttgttacact aaccatatga
    15361 aggctgacca aaatgatatg gaaaacttag ccatactatt aacaacagca ggatgtacgt
    15421 attttatggg aatacctcat ggagatgatg ttatgcttaa ctatcaaaca acaggatacc
    15481 atgaaacagc atcacttaga gaaatgtttg gactaacagc aataaaagaa tttgatgctt
    15541 ggatggaaaa gatgggattc tctaaagatg gtaagttaac agagttggcg ggagacgcat
    15601 ctgtattatt aggataggag gtatttaata tgaatgagaa ggatttaaaa gcattggtag
    15661 aacaattagt tggacaaatg gttggagaat tagatactaa tgttgtgtct gagactgtta
    15721 aaaaggcaac tgaagttgta gtagacaaca atgcttgtat agatgatata acagaagttg
    15781 atataagaaa gcaattacta gtaaaaaatc ctaaggatgc agaagcttat ttagatatga
    15841 aagcaaaaac acctgcaaga ttaggtatag gaagagctgg tactagatat aaaacagaaa
    15901 cagttttaag atttagagca gaccatgctg ctgcacaaga tgctgtattc tcttatgtag
    15961 atgaagaatt tataaaagaa aataatatgt ttgcagtgga aactttatgt aaagataaag
    16021 atgaatactt aacaagacca gatttgggaa gaaaattttc tccagaaact ataaataata
    16081 taaaatctaa atttggtaca aatcaaaagg ttttaatatt agttggagat gggcttagct
    16141 cagctgcaat agaggcaaat ttaaaagact gtgtgccagc tataaaacag ggtctaaaaa
    16201 tgtatggtat agattcaagt gaaattttat ttgttaaaca ttgtagagtt ggtgctatgg
    16261 accacttagg tgaagaatta ggttgtgaag ttatatgtat gttggttgga gaaagaccag
    16321 gattagttac tgctgaatca atgtcagcat atatagctta taagccatat ataggaatgg
    16381 cagaagcaaa aagaacagtt atatcaaaca ttcacaaagg tggaacaact gcagttgaag
    16441 caggtgctca tatagctgaa cttataaaaa ctatgttaga taaaaaagct tcaggaatag
    16501 accttaaata aagtcgaggg agtgtagaat atgaaaaatg atgtaattcg tcctaatata
    16561 ctaggaatta aaataatttc aaatataagt ccagaaatgg cacaaaaact agaattaaaa
    16621 tcacatcaca aaagcttagg cttaataact gcagactgtg atgatgttac gtatacagct
    16681 cttgacgaag caactaaagc ttcagaagtt gatgttgtat atgcaaaatc aatgtatgca
    16741 ggtgctgcaa atgcttcaac aaaacttgct ggtgaagtat taggaataat agcaggtcca
    16801 agcccagcag aagtaagaag tggtctaaat gcagtagttg attttctaga gtatggagca
    16861 acttttataa gtgcaaatga tgatgattca atagcatact atgctcactg tgtatcaaga
    16921 acaggtacat acctttcaga ggtagcagga ataagagaag gtgaagcatt agcttattta
    16981 gtagcaccac cacttgaagc aatgtatgca ctagatgcag caatgaaagc tgcagatgtt
    17041 aagatgtgtg aattatttgc acctccaact gaaacaaact ttggtggagc attacttaca
    17101 ggttctcaat cggcttgtaa agcagcatgt gatgcatttg cagaagcagt aaaatcagtt
    17161 gcagacaatc caacaggatt ttaaggatag ttagatggat gctataggct taatagaagt
    17221 aataggatat gttgctgcaa tagaagcttc tgatgcttgt ttaaaatctg caaatgttaa
    17281 tattgtaaga gttgataagg ttggagcagg tattgttact ttaacaatat gtggagatgt
    17341 cggtgctgta aaagctgctt tagaagcagg tgaaatagca gcttccagag ttggtacatt
    17401 aagaacatca catattatac cgagaatcca taatgaagta acaaatgctt tattcaaaac
    17461 taaagaacct aaagtctgtg aagtttcaga agataaagaa aaaaactttg agattacatt
    17521 ggaaatagct gataatgtat cgaaaaattt atcagaaaaa gaaaatgtaa ttttagatgt
    17581 caatgaaaac agtggagata ctgaaaattt atatagtgat atagataaaa caaacaaaaa
    17641 aattgaaaca gttgatgata gtttaacaga agctaatgag gaaaaaatag aaaacactaa
    17701 tgataaagaa gtattggaac aagttaaaat agaaaattcc gattttgata gagatgacct
    17761 atcaaagaac agtgtaaaaa aacttaaagc tatggctaag aaattagatt cttcaataac
    17821 ttataaagat ttaaatgttc ttaaaaaaga agaattaata aacttagtta aaaagcttag
    17881 tagaagggat agatagttat gacactttta gataaagatt tagtatctat acaagaagta
    17941 agaactcttg taagaagatc taaagtggct caagagaaac tttctaaaat gagtcaagag
    18001 caaatagata aaatagtaaa agctgttgta gatgcagcat ttaataatgc tactaaattg
    18061 gctaaaatgg caaatgaaga aactggattt ggaaaatggg aagataaagt aattaaaaat
    18121 acttttgcat ctatgggagt ttataaaact ttaaagaaca caaaaactat tggaataatt
    18181 ggtgaagata aagaagccaa tacgatagat atagctacac cagttggagt tgttgcaggt
    18241 cttatacctt caacaaaccc aacatcaaca gtaatataca aaactataat atctctaaaa
    18301 gcaggaaata ctatagtttt ctctccacat ccaaatgcaa aaaactgcat acttgaaaca
    18361 gttaatataa taagtgaggc tgctataaag gctggagctc cagaggattc aatattatgt
    18421 ataactaatc caagtatagt tggaaccaat gaattgatga aacataaaga tacaaactta
    18481 atactagcaa ctggaggaga agcaatggtt agagctgctt actcttcagg aacaccagct
    18541 attggagttg gaccaggaaa tggaccagca tttatagata aatcagcaaa tgttaaatta
    18601 gcaatcaaaa gaataataga ttctaaaact tttgataatg gtgttatatg tgcatcagaa
    18661 caatctatag taatagaaaa atctatggaa gaaactgttt taaaagagct taaaaatcaa
    18721 ggtgcatatg ttttaaatga agaggaaagt gaaagattag caaaattcat attaagagct
    18781 aatggtacta tgaatccaca aatagttggt aaaagtgttg aggtaatagc aaatttagca
    18841 gacttaacaa atgtacctaa aaatacaaaa gttctagttg caagagaaaa taaagttggt
    18901 cacaatgtag cctattcaag agaaaaactt acaccaatac tagcgttcta tgttgaagaa
    18961 aatgtagaag ctattatgaa cagatgtaga gaaatattgt taaatgaagg tgcaggtcat
    19021 acattctcaa tgcatgtaaa tgatgaagaa ttggtaaaaa gatttgccct taatatgcca
    19081 gtatcaagaa tacttgtgaa tactccttca gcacttggag gaataggtgc atcaacaaac
    19141 cttgtaccag cactaacact tggttgtggt gcaataggtg gaagttcaac ttcaaacaat
    19201 ataggaccac ttgatttaat aaatgttaaa agagtagctt atggaatcaa agaaatagaa
    19261 gaacttggaa gagataaatc tcaagttgaa aaatcaatgt ttgactcaat ggataaagaa
    19321 gaattaataa atcttcttgt tcaaaaacta gtcaaagaac tagcataact aaaataaaca
    19381 atgaaactta tggctatcgc tataaatttc taaaaatata aactataaaa aactataaaa
    19441 ttaaattttt ggaggataag attatggcaa gtgcaaacgc attaggaatg atagaaacta
    19501 aaggattagt aggagcaata gaagcagcag atgcaatggt taaagctgca aatgtacaat
    19561 tagtaggaaa agagcaagta ggtggaggat tagttactgt aatggtaaga ggagatgttg
    19621 gagctgttaa agctgctaca gatgcaggag ctgccgctgc cgagagagtt ggagaactaa
    19681 tatcagttca tgttatacca agaccacact ttgaagtaga tgctatatta ccaaaggtat
    19741 cagctgagta atataagaat aattataaaa tttaaatttt gattgaaaaa gaggctatct
    19801 caaaaatgag tcttactaat aaactcaatg tattttgagg tagtcttttt tatacatcta
    19861 ataggagatg tgataaaatg ggtgttttaa cagaaaacga agtaaaaaga aaaattggaa
    19921 aaaacaaaaa taatataact gaattttata tagaaaaagg tcaaataata actccttctg
    19981 caaaatctta tttagctgag agaagtattg agcttaaata tgttgataaa ctttcagatg
    20041 taaacaatga acctaaagaa gttgtaaaag aagtagttaa agagaaaaaa tataaatata
    20101 ctactgtatt tggcgccaaa ttggatgaaa aaccagaaca tatgactcaa ttaaatggaa
    20161 atcttttagt ttttaaagac cataaaagaa taatattgag aggaaaaata gattctcttg
    20221 aatcagaaat actaaaggta cagatacttt gtcaaaaact agatatgcca aagcttgtta
    20281 aggaattgca agaagtatta gactttgtaa gaaatataat gagatgtgaa gttttagatg
    20341 aaaagctagg ggactttaaa cttttaggat taactcctca agaacttaga gaacaatctc
    20401 actatcctaa aaaatacttt ggtataggac atgagttccc aagttatgaa atgggagaag
    20461 tagtagtagc tataaatagt ataagaagta atacacgaga ggttgaactt gcagcctatg
    20521 aagcatttaa gggtgagtat ggaaatgttc acagagaaga tttaataaag gcacttaata
    20581 gattatcgtc agtattttgg ataatgatat ataaggttag aactaataag tataagtagt
    20641 tggaggacat aatggagaat ctattaaatg aaatagtgga agaagtaata actagagtta
    20701 aaaaagaagc atttatagaa gttgaagcat caggaagaca cgttcactta agtagagaag
    20761 atgtcgataa attatttgga gaaggatata ctcttacaaa actaaaagac ctatctcaac
    20821 caggtcaata tgcatgtaag gaaagagtta caataactgg tcctaaagga agtataaaaa
    20881 atgtagttgt acttggacca tgtagaaatg aaactcaggt agaaatatct ttaacagatg
    20941 gttcaactct tggactaaaa gctcctataa aacaaagtgg agacttagaa ggtactttaa
    21001 gtattaaaat atcaacacaa tatggtgaag ttgaacttga taaggggcta atggttgcta
    21061 aaagacatat acacatgact cctaaagatg ctgaaaaatt caatgtatgt gataaagaga
    21121 tagttgaagc taaggtgatg ggtcaaagac ctttaacatt tgatgatgta gtaataagag
    21181 tgagtgacag ttttaaaact tatatgcata tagactatga tgaagccaat gcatgtggtt
    21241 attcaaaagg aactgttgct aaaataataa agaaagcata aatttaacct actatataaa
    21301 ttacctctag ggaggattta atatgaatta tgataacctt gtagatttaa taacggaaga
    21361 aatctataaa aaaataaata gtaatgaaat aaaaatatct aataaaccta aagctgtgat
    21421 tgtatttgaa caagataaca ataaatttaa cttattaaaa gatgaatttg aaatagtaga
    21481 atttgataaa agtataaggg aatgtgaaat agtgatagtt tcaagacttt gtatgagggg
    21541 gctatcgaat atagcacttg gaaattcaac aagtgatgaa gaaagattta tactaaaaat
    21601 gattatgaag ggcaaaaaag tatatgtcct agatgaagga attgaataca aaaaatataa
    21661 ggatactgca ccaaaagcat tatataagaa atttatgtca tttgaagatg aaatatgtaa
    21721 atttggtgta gaaattataa aagacttaaa tgttataact aaaaataagt taaatataaa
    21781 gaaagaacta gaaagtacta gaggttctaa aaaagaagat acaaaagttt tagataaaga
    21841 tgttttaaat ttaaccagtg tcgaaagtgt aaaaatagat aatgaattta gtttagattt
    21901 aaggaataaa aaacttatat cggaagctga cttaagaaaa ccaactataa atggagttaa
    21961 aaacatatta gttaataaaa aaagtataat aacaccatta gctgtagatt ttatgagaat
    22021 acaccatctc aaactaaaga aactgtaagg aggtaatttt atggatatag gaaaagttgt
    22081 aggtaatgtt tgggctacaa gaaaagatga aaaattatgt ggccaaaaac ttttagttgt
    22141 aaaaatttta aaaactaaag acacatacaa ggaaggcttc atggttgcag ccgataatgc
    22201 aggagcagga aatggagact tagttcttat atccaaaggt tcctcagcta gagagtcgat
    22261 tgaaaaatct catgttccag tagatgcaac tatagttgga gtagtcgatt cgtttgaggt
    22321 gtttgatgaa taaaagtata ggagctatag agtttaaaag cattgctaaa ggtatagaag
    22381 tatccaatga aatgataaag aaatcttcag ttgatgtatt gtacttaaaa agtatttgcc
    22441 caggtaaatt tctaataata gtaggtggag aaacttctta tataaatgaa tgtgtagatt
    22501 atggaataaa acttggagaa ggatatattg tagataactt cgtaataaat gcaatttcac
    22561 aagaaatatt agatggattt aaaaataagt atcaaaagct agatagtata gtctctatag
    22621 gcgttgttga aagtagtaaa gtatgcgctg gaataaaaat gcttgataag actttaaaat
    22681 ctggcgactt agtattagta aaacttcaat tatcttttgc tataggtggc aaattagtat
    22741 atatagtagc aggagattta agtagtttag aatatgcatt aaaagaaagt gaaaatgtag
    22801 taagagaaaa agaagtaata tataagactg taataccatc agtagacagt caaataataa
    22861 aaagtctaat aaaataatgg ggggaattat gagtataaac gaaattataa tctatgtaat
    22921 ggtagtcttc atggtacttg gagctataga taaatgtata ggtaacaaat ttggtcttgg
    22981 agaacaattt gaagaaggta taatggcaat ggggtcactt gcagttgcaa tggttggtgt
    23041 tatatgttta gcaccagttc ttgctgatgt attaagacca attgtagtac cagtatttaa
    23101 tatacttgga gctgacccag ctatgtttgc tggaagttta ttagctaatg atatgggtgg
    23161 tgcgccactt gcacttgaac ttgcgaaaga ccctaatgct gggttatttg gtggattaat
    23221 agtaggggct atgatgggac ctacaatagt atttataata ccagttgcgc ttggaataat
    23281 tgaaaaagaa gaccaaaaat tcttagcaac aggaatactt gcaggtataa taacaatacc
    23341 tattggagca ttcgttggtg gattagttgc aggattcgag gtaatgatgg ttcttagaaa
    23401 cttagtgcca ataataatat ttgcagtagt tatagcactt ggattattaa aattcgaaaa
    23461 tgctatgata aaaggattca catactttgg aaaaggtgta gtaatagtta taactttagg
    23521 acttgctgct gccatagttg aagctttaac aggaatagtt gtaatacctg gaatgaaacc
    23581 aatcagtgaa ggtatagaaa tagttggaga tatagcaata gttttagcag gagcattccc
    23641 attagtgttt gttataacaa aggtatttaa taaaccatta atggctttag gaaaagttct
    23701 tggaatgaat gatgtatcag cagcaggcct tgttgcaagt ttagctaact gtataccaat
    23761 gtttggtatg atgaaagata tggacaatag aggaaaaata ataaatgtag cattctctgt
    23821 atcagcagca ttcgtatttg gagaccactt aggatttacg gcaggattta attctaatat
    23881 gataacacca atgatagttg ctaaattagt tggtggcata acagcagtat tgttagctat
    23941 ggttatcgca aataagacac taaagaagga gaatgtataa gatggatata tcaaatatag
    24001 ataaaaattt aattgaaaca ttagtaagac aaataataga agaaaaaata agtggaacta
    24061 aagacacagt agattttgtt agaaataaag acattagtgg aataacttct ataaagttac
    24121 caactgtaaa agttagtgaa tctgatagat tagatacagg gaatccaagt gatgtagttt
    24181 acacaaaaga tttatttaca ttagaggaaa gcccaagatt aggttgtggt atgatggaaa
    24241 tgaaagaaac aacttttgat tggactctaa actatgatga aatagattat gtaatagatg
    24301 gaactttaga tataataata gatggaagaa aggtttctgc ttcttcaggt gaattaatat
    24361 tcataccaaa aggaagtaag atacaatttt ctgtacctga ttatgctaga tttatatatg
    24421 taacatatcc ggcagattgg gcatctcaaa attaataaaa atcaagttaa gttaataata
    24481 atcaaataaa taatttaaaa tacaaactct taaataagca cacatattta aaaaagctat
    24541 gaattaaaat tcatagcttt ttttataaag aatgttatat tttagacgta ttttttctat
    24601 atttactggg agacatatta tattttttat taaataatct aataaagtgc tctacatttg
    24661 gataaccaat actattttac tgataatctt ttccttatca ctaatcttac attttaaaat
    24721 attattttta ctcgtaatat tatcataaga atttgtttct tatttaaaac taattagaat
    24781 tataaagttt attgccatgt tattaataaa ataaatccag ttaaatcgag tgctagttaa
    24841 agtaataaga aacttttaca atggtttcct ttatcgattg aaataaaagt taatatggta
    24901 taatatctaa agagagaatc ttatcaatta gaatatgcat agaaacaagt ggcttaaaag
    24961 gagacgttat atggaagaga tagtaaagaa ggaacaagca agtatgaatg atattttttt
    25021 gtatcttaaa gctaaatcaa actcattata taaatttgta atattatata atgagtttat
    25081 caataaacct aaagattatg gaactgggga acttataaac atggttgaag tacatatgct
    25141 aacagcaatt gaagaaaatc caggaataag tccaactcag ttagctaaaa tatggaacag
    25201 aactaaaggt gcaatatctc aaactatatc taaattggag aaaaagggtt atataactaa
    25261 agaaaagaaa gaaggaaatg caaaaactat attactatat ccaaccacat caggagtaga
    25321 gttaagtaag gcacataaac tatatgacac catagatgtt acaagaacat ttgaatactt
    25381 aatcaaggag tgtacattag aggagataga tagtttttat aaagtaattg atttgtttat
    25441 taatttatta gaagaatctc cgcaggaaaa taatgattct gaaaaagtgt agctgagatt
    25501 gaagttgaat aaagagaaat agatattata gaagtagtac ttaagtacac attatataaa
    25561 aatataatag gtataggatt aaaaagttta gtggtttaaa gtttaaccac taaacttttt
    25621 taatgtctat aatctactat tatttaattt actaaaaata aaaaaactca ttatattaag
    25681 ataaaaatag aaaaataact agaaaaatac tataatatat cagtttaata cagaaaaaag
    25741 ttaaaaaatt tgagaaaaat aaaaatgaaa acgttttata ttgacataga gaaaaagtag
    25801 tgataccatt taaatatagt ttagtagcta aactatattt aaattataat aactatttta
    25861 gggggatgtt atgaatttaa aacaattaag tgaaaaatac gaagaatatg taattcaaat
    25921 gagaagagaa tttcataagt atccagaatt atcttttaaa gaaataagaa caacccaaag
    25981 aataagggaa gaattacaaa aaataggggt cccttttgta tctattgaac caaatatcgt
    26041 aatagctact atacaaggca aaaatgaagg taagacaatt gcaattagag gagatataga
    26101 tgcgcttcca atgcaagaag attcagatgt tgaatacaaa tcagaatatg atggaataat
    26161 gcattcttgt ggacatgatg ctcatggagc tatgttacta ggacttgcac atatgctaaa
    26221 tgatataaga aaagatttaa aaggtagagt attattagtt tttcaagcag ctgaagaagt
    26281 tggtggtgga cacaaggaga taatacagta ctttaaggaa aatggaggac cagatagatt
    26341 aatagctact catgtttggt ccgatattga agctggtaaa atttctgttg aaccaggacc
    26401 tcgtatggct ggtgggtctg gttggagaat agacataaca ggtagaggag gtcatggttc
    26461 tagaccagat caaagcatag atcctataaa gccagcttgt gatatagttt taaaagtatc
    26521 ttctatacca gttaatcata taagtgtact agaacaatgt gttgtacatg catgtgcaat
    26581 acatggagga actacaatag gaaatgttat tccaaacaat gcagaggtaa taggtggata
    26641 tagatatttt actgaagaat caggcaaaaa agtgtttgac attataaagc aaatgagtaa
    26701 tggtgttgga caagtttatg gagtggatgt gaaggttact catactggag gcataggacc
    26761 tgttatcaat gatgaagaag cagttaagat ggctaaagaa atagtttcta atatagatgg
    26821 attggagtta gattcttatg agccaatatg tgcatcagat tgttatggtg aaatattaaa
    26881 agagtattct ggcttttatt gttatctagg ggtaggtaac aaagaaaaag gaataatata
    26941 tgcacaacac catcctaagt acaatataga tgaagataca ttaaagttag gttgcgaatt
    27001 tatggctaaa tatgcagttg aatttttaaa taaaaataat aactaaaata aatcgaattt
    27061 tataaatggg gggatgaaaa tgcaaggtgc attaaaggaa aataagaaaa aaagtggtgg
    27121 aggattttta ggatggattg aaaaagttgg gaataaaatg ccacatcctc tagcattatt
    27181 tacatatatt acgttgatag tagtagcatt atctgcaata gcaagctttt taggtttttc
    27241 agcaacaagt cctgctacag gaaagttaat aaaagttatg aacttaataa gtgcaaaagg
    27301 tttagtacta tttatgcaag agtttgttaa gaacttccaa aacttccctg tgcttggagt
    27361 agttttagtt atggcagttg ccacaggagt ttgtgaaaag acaggatttt tttcaactgc
    27421 cataaaaatg agtttatcaa aagttaaggg gaatgcggtt gtatttataa tagcttttat
    27481 aggagtattt gctaatcaag ctggtgatgc tgcttttgta ttagtaccaa ctcttgcagg
    27541 agcaatattt tatggattaa atagaaatcc attagctggt atattctgtg gatttgcatc
    27601 agttggtggt ggatttgcaa cagctgtaat tcctggggga tgggacgtta cgctaacgcc
    27661 aataactgta tcagctgctc aaactattca acctgcattt gatatgacat tattagctag
    27721 ttattatgca ctatttgtat ctgcgtttat agtagctaca gtatcaacaa tagtaacggt
    27781 taaatttata gaacctaaat taggtaagta tactggtaaa ccagaaggta tagatgataa
    27841 tcaaggtttt gaggtcacaa aagaacaagc aaaagcagca aagttagcag gttttacagt
    27901 tttagcttat gtagcgttat taattgcttt gtgtatacca gctaatagtt ttttaagaag
    27961 tccagaaggt tctttaatat ttggagcacc acttatgtct tgcttacagt tttttatagt
    28021 aatactattc ttcttgccag ggattgtgta tggaatgagg gttggtaaaa tcaagactgt
    28081 aaaagactta aatgatatat tatgtcaatc aatggcagca atggcaccgt ttatcgtact
    28141 tgcaatagtt ataggtcaat tcttaacgct attctcagtg tctaatttag cacaggtact
    28201 agctataaaa ggtggagcat tactcaactc attgccacta ccaccacaag ctataatact
    28261 gctattctta gtactagtag cgtttataaa tatatttgtt ataagcggaa gtacaaaatg
    28321 gatgatattt ggaccagtat ttgttccaat gttaatgcaa ttaaacatac atccagcatt
    28381 tactcagttt gtatatagat taggagattc tgtaaccaat catttatcac cattaaatgc
    28441 attctttata atacttttag caacagtcca aaaatacgat aaaaatgcag gtatgggaac
    28501 tatattctca gctatgatac cttacactat aggttacttt gtagtacttg cagttttagt
    28561 agtagtttgg atgacaatag gtataccagt aggaataggt ggacaagttt ggttataaaa
    28621 catatttaat aattttggga ggaaagaaaa tggaaacaac tgaaataaga tacaattttg
    28681 atgaagtaat agatagaagt ggaacaaact gtcttaaata tgatcttaag agtcaattta
    28741 tgccagaatc tccagaagat gcactaccac tatgggtagc agatatggat tttgcatgtg
    28801 cccctgagat aattaatgca atgcatgaaa gaatagacag aaaaatattt ggatatagct
    28861 ctcaacaaac tgatgattat tatgaagctg tatgtggatg gtttaagaga agatttgatt
    28921 ggaaaataga aaaagagaat atattcttta gcccaggggt tgtgcctgcg ttaggatttt
    28981 tcacacaaat attaacacaa aagggtgatg gtatcataat agaaaagcct gtatactatc
    29041 cttttgaaga taaaataact aacaatgaaa gaaaagtagt taatagtcct ttaaagtttg
    29101 aagatagtca ttattctatg gattatgatg gatttgaaga attagctaaa gatgaaaata
    29161 ataaggtgtt tatattatgt agtcctcata atccagttgg tagagtatgg aaaaaagaag
    29221 agcttagaaa aatagtagac atatgtaaga aatatgattt gtggataata tctgatgaaa
    29281 tacattgtga tattattcgt aaaggtgaaa agcatatacc attagaagta gcatgtcctg
    29341 attataaaga tagaataata acttgtacag ctccaagtaa gagttttaac ttagctggta
    29401 tgcaattatc aaatatagta atcaataata aggaattaca agaaaaatgg atgcttgaaa
    29461 cagattctaa attagctata ttcctaccta atccattcgc aatagttgct actaaagttg
    29521 cttataatga ttgtgaagat tggatgaatc aagtaaatga gtatatagat ggtaatatta
    29581 aatatgtaga agattttgtt aatgagtata tgcctaaagt aaagataata aaatctcaag
    29641 gaacttactt agtttggtta gactttagag ggtatggatt agatgcaaaa cagcttgaat
    29701 atgtaatgct taacaaggcg aaggtattgc tagatgaagg atacatattc ggagaagaag
    29761 gagaaggatt tgaaagaata aatgttgctt cacctagaac aattatagaa gagtgtatga
    29821 atagaataaa gtgtgcattt gaaggattat aatagtaata tctaaataat atatttgtgt
    29881 attttaaaaa aagactatgc taaaaaaata tttcaaagca tagtctttta aagttttatg
    29941 atgagtttaa aaaatttcaa aacgttacta ttcacttaca tgtttatatt agaaataatt
    30001 ccacaatata ctcattttct aaagttgcac ttttatacac cttgcttcac caatatcatg
    30061 tgtaaccaaa atagtagact tattctcatt cttaataata ctataaacat catcacaaac
    30121 taataatcta gtctgataat caagagctga aaaaggttca tctaaaagta gaatatctgg
    30181 atttacagaa agtgttctaa taagcgcaac tctttgtctc atacctccag ataattcttt
    30241 tggatacata cttctaaaat cccataatcc ataagtcttt aaaaggcttt caactctatc
    30301 taaagatttt ttatcttttt tgccttgaat ttccaatcca atagttatat tatccattat
    30361 atttctccat tcaagcaaat tatctttttg aaacatatat ccaatatttc cagtaatctt
    30421 tatatcacca ctagtcggtt ttaaaagatt agtaagaata tttaatattg tagatttacc
    30481 acttccagaa ggaccaagca aagttaatat ttctccttct ttcaagttaa aattgacatc
    30541 ctttaatact tcaagctcgc cttccttagt gtagaagttc atatttatat ttttaacttc
    30601 tactatgttg tcattcatta tgccaccccc tataactttt agctcgtata tattatgtta
    30661 ttaacaatat gacctatttg taccattttt cataaatata atataaatat tttgtttatt
    30721 tacgtatttt cttagtaact tgtacgtata aattatagat aaataaatta taaggtaggg
    30781 gataaatttg agtaacataa taacgaattt aatagagtca atatttacta atccaataac
    30841 tatattgttt ttacttgcaa taactgtgta ttctgttttt aaaataatag aaaataacag
    30901 agtatattca tttgtaagtt caaaattaga cgaaatcaat agagactata agacaagtga
    30961 gttttataaa aaggtaaggg atgactacta tacatatagt aaagaaaatc cttatgcaga
    31021 cgtaaatata acttcattta tagaggaagt tgtatctgat ttaaagcata ataatttgcc
    31081 attgttagaa aaaattagaa gtataaaaaa ttcatcttca ataagtatat tacttggggt
    31141 tttaggtacg tttgttggtc tttctacaat gcttttatgt gttgatacta aagacattat
    31201 aaattcactt ccttcaacta ttagtagtat gcaaactgca tttacaacta gtatatttgg
    31261 agttgtattt tctctaatta taggttactt tactaagata aaagattgtg aacatgtttt
    31321 gatacaaata atgttaaaat ctgaaaattt actaacatct gaaataactc attttaagtc
    31381 agaaagaatg gatttaaaag tagaagaggt aaaaaataca ataaaacaaa taagtaagtc
    31441 tatagaagct attgaaaaat ttgataaaat atctaaagat ttaaatgact ttaatgatga
    31501 atttatcagt ggtatagaag ctttaaaaag ccttttagaa ggttctcaaa gttctattaa
    31561 gacatttgac cagagcgtaa gaaaattaga taaacagttt aatattttaa atataaaatt
    31621 tgtaaagctt tttgataaat atgataatca agataatata aataaagaga ttttatttga
    31681 tataaaagaa tcttcaaaaa atatatacaa tgccactgaa agccaattca aaattagaga
    31741 ttatataaaa aatataaatg caggatttgc tctatatgaa agaagtgctc aagacttatt
    31801 aactaaatta atgacccatg aaaataaaat ctctcaaaat caaaaaatcc ttttagatga
    31861 aaagtttacc ttagatgact caataaaaaa tctctcaagt attattgaaa acttttctaa
    31921 tgacctacaa gttaaactgg atatgatgtt tgaaaattct ttagatattc aagataagtt
    31981 agatgttatg tttaataact cttttatgaa tgatgaagtt cctcttgata gtgaaaaatt
    32041 atttaaggat gatgttaata atgtatttaa tccttttagt gaagaaattt atgagataga
    32101 ggataaagaa ataaaggtca taggtgagga tgagttaaat gaataataaa tatataagaa
    32161 ctgttaacag ggaatttgaa aagagtagct tttggccaac atttacagat ttattatcta
    32221 ctgtattgat ggttgtaatt cttatcttat ttagctcaga aagtatttca ggttctgttg
    32281 aacaagattt agctaagaat gtcaatgctt ctgttgaaga aacttttaaa aaaagtggaa
    32341 tacctgtcaa ggtagataaa tctaatgggc aagtaacttt tggtgaaaaa accatgtttg
    32401 atatagatag tgatgtttta aaaccagagg ctaaagaaat gctaaaaatg tttgttccaa
    32461 agtacataga gactatttat aaagattatg gtgactatat atccaaaata gttatagaag
    32521 gtcatacaga tgatgtggga agttatatat acaacttaga tttatcgcaa agaagagcat
    32581 atagcgttgc taaatttata gtgggagatg aaataggtga ctataaatac aaagataaag
    32641 tgactaagca tattattgca ataggaaggt caaaagctga actcatcaaa aatggtgaca
    32701 atagcgtgaa tagagatgca tctagaagag tagaactaaa atacgaaata aatattaatc
    32761 aaaataaata attaaatttt tataaaaaaa aagaaggcag ttggtgtgag ctttaagcct
    32821 tctttaagga aaaagtttat ttatttttgt tgatacttaa catattatag tttttagaag
    32881 cagtttgcaa tatattaaac gtaaatggtc gtttaaaatg cataactgga tactactgat
    32941 gtaaaatatt tcattttata taatataaaa attatacagt gtcaattttc tatattattg
    33001 tactataatc tattatttaa aatattatgt aaaaaaatat cataaaaacg catatcatgt
    33061 tataattact agagtattat gaatatggag gcgtagtttg tgatagaaat aagtataaaa
    33121 aataaaaaaa attctaaaat taaaactttg atacttttat tgatagtatc tatatcgatt
    33181 tatttaactg gttgtactac atcagataat ggaaataatc aatcaaataa taatgattct
    33241 ttgtctagta gtatatcaag tgataagaat gtaaaaattc attttattga cactggaaat
    33301 agtgatgcaa tattgattca agatggtaaa acttttacat tgatagatgg gggagataat
    33361 gatgatgagg gattaatggt agattaccta aacaatcaag gtgtaaaaga tattaaatat
    33421 cttatagcta cccattctca tgcagaccat ttaggtggac ttgattctgt tgtcaaaaac
    33481 tttaatatag aaaatgtttt tgtatcgaat ggttcagcag aaacaaagag ttatagggac
    33541 tttataaatg ctttagcaaa taagggttta tccccaagtg taccgcttga aaataataag
    33601 ttctatttag aagattctta ttttgaagtt ctaaatacaa atgggggaga tactactaat
    33661 gaacaatctc tagtccttgt atatactaat gggaatgata aagttttatt tacaggtgat
    33721 gctgaagaag gtaccgaaaa agaaatacta cctaagcttg agaaagtaga ccttttaaaa
    33781 gtagctcatc atggttctcg tagtagttca tctcaagagt ttttagataa agtaaatcct
    33841 gaatatgcgg ttcttttagt aggcaagggt aattcatatg gtcatccaca tcaggagaca
    33901 atgaataaat taaaaaaaat gggagtaaaa gtacatagaa gtgatgagtg ttcagatata
    33961 atatttgaat caacaggtga tggagtattt acaagttgta aagatggaag ttataataaa
    34021 ggcgttagag aagatggaaa ctctggaaaa tcaaacagta atacaagtaa aaatgattct
    34081 tttaaaaata aacaaaatac atccaattca gaagaaatag tgtattttac tccaaaaggt
    34141 aagagttatc actctacaaa aaattgtagt gggctttcaa gaagtaaaaa aatattatca
    34201 ggcacaattg cagaaagtaa gaaaaatgac ccatgtgata tatgttatgg aaaataacaa
    34261 aaaaacaacc aatttatcta taaagcttct gaactttaaa tcatttaaaa aataaaataa
    34321 atgcataaaa aaataagcta taatcaatag ataacacatt ttatctatac gaatagctta
    34381 tttttttaag tattttttaa tagctattta ataactctaa atacaccagt tacaatacct
    34441 acaatttcaa cttctgagtc attgagcata attggttcca taaaatcatt ttctggctga
    34501 agtcttatta aatttccttc tttaaaaaac ctcttaaccg tagcagattc accatttata
    34561 agtgcaacta ctatctgaga atttaaggct gtattttttt tgtctactac aacgtaatct
    34621 tcatctaaaa ttcctgcatt aatcatactt tcgcctttta ctcttaatac aaaattgtta
    34681 ctgcccttta ctaaactggc agggaatgga atgtattcct ctatgttttg ttgagctaaa
    34741 atgggttctc cagctgttat ttgacctact aaaggaagct ctattatttc ttgattagct
    34801 ccagaaacat catttacttt actacgttct aaaacttcaa tagctcttgg tttagtaggg
    34861 tcctttctta tgtatcccag tttttcaagt ttatttagat gagagtgcac agttgaagta
    34921 gatcttaacc ctacagcagt acatatttct cttacagcag gtggataacc ttttaatatg
    34981 atttgagact ttataaattc caatatcaag acttgctttt cagttagatc taaatacata
    35041 acatcactca tttccaaaca tattttgttt ttatttccat acactttata tttttaatta
    35101 taacataatc catttatatc tgcaaacatt tgttcctgat ttttaatcgt cctcaatcca
    35161 ttcaaaattc ttgactatat cacgttttac atttttctta tgagctgcat aaagctgagt
    35221 agttgtgaca ttatcatggt caagtaagtt ttgaacatca tatatagaaa atcctgtttg
    35281 gattagagaa gttgcagccg ttgctcttaa tttatgggga ctatatccat tgtctctagt
    35341 agtatcaagt ggaatagatg tatatttttt taccagtgtt cttatagcct ttgctgtaat
    35401 tctcttattt tgaagagaca aaaataaagc atctttttct tcatcattta atagttcatc
    35461 tcttgttctt tcgttttgca aataatcttt tattacatgt tcacaagtat gatttatagg
    35521 cattaaaact tctttcccac gttttctata tattttaaat tcacctcttg aaaaattaaa
    35581 agaggagata ttgagttctc taagctcatt taatctaagc ccgtatgtaa caaataatgc
    35641 tagtatagct ttgtcacgta atttagtttt tctccaatat accttttctt tctctgtaag
    35701 cccttcacct gtttctactg attcaagcat cttagcaact tcatctatct caaggcgctt
    35761 aatagcatct ggctgaggtt taggaagttt tattggattg aatccatcag ttatattatt
    35821 atctatctga gagtttctgt ataagaattt aaatagagta gagatggatg atttttttct
    35881 tgctaaagct ctattgttat tttcaaaaat caatgtgttt ttttctgtat ttttgtaata
    35941 tctactgcaa taatcaccta agaataaatt tatatctctt gattttattg tattaaaatc
    36001 atcttctgta atgtctttta cacaatctgc atttgttaat tctttggttt caatcaaata
    36061 tgaacaaaaa aaattaatat cttctaaata agcaagtcgt gtagaaactg caacagaacc
    36121 ttttaaatat ataaaataat ccttcataaa tacaggaagt ttattttcca aaagtagaca
    36181 tttttctatg agttcatttt ctttgataac aatattatca ggtttatctg atttattatg
    36241 tacttttata attttcttat cattattcaa aattaaacct cctaaaacta aaatataaat
    36301 cttttatatt attttttgat atttatacca agtgagtata aatatttaat ttaatcattt
    36361 tttacatttt taagagatta gcagtgcttt agatgaaatc atcactaact attccctaaa
    36421 tccacattta aagactagtt gaatttaagt actctttttt atttctcaat atatttatag
    36481 aaatatttta aaatatattg agaaattttt tatgctctac taaaatcttt tttatataat
    36541 atttttatat gtttctaacg aaaccaaata ttagtaaaat atgtatttat ttaactaaag
    36601 tttttaaatg ggctgactaa gcttaaaata taggatatta tgagagttac tattgaaaaa
    36661 ataaacccta ttgccataaa gaaacttata aatatgttat acttaactat taaactggat
    36721 atattcaagt tatcaaatcc aaataagtat gtaattgaac ttattacaaa aataactata
    36781 actataaagc tcagaccatt taagctattt tttaaatcag cactactaag tgacatatgt
    36841 gtagatatag aatacattaa aaacataaat ataaaatact tcaatgaata tacactaggt
    36901 gttaacaaca ttattcttat aaaattggaa atatcaccta aaataatgtg tataaaacca
    36961 tttatattta aattattaat catacttaca tataacttta aatttatatt ttgagtcact
    37021 ttcatataac tatctggcag taatatctta aaaattaaaa taatcattat tgttccacct
    37081 ataataggtg caattcctat aaagaaattt cctatacttt gataaagatt atctttttta
    37141 tagctatgac ttacatatcc tagtatacca tcatttttac tttctattgg tctgaaaaac
    37201 ttaactgaat ttattttatg catgaaaatt aaacacatta tcaaatgact caattcatga
    37261 acaaatgttc ctatagctcc agttacaata attccagttt ttccaaaaga tgaaaagata
    37321 aatttattat ttagattttc tgtaatgcta aaaatcaatc caaatacaat aaatattcct
    37381 atgaaacaaa aaatatttat tacacttatt tttaaaattt cgattatata aatcataagt
    37441 taagtcctca tgtaaaagta tttaactact ctacttcata tccattacag cttaaaattt
    37501 tacaagcatt ttctatatcc ttttctttta ctaagatata gtctgtatca tacgtagaaa
    37561 ttgcaaatat gcttattttg ttgtctgcta acaaactact taacttagat aaaattccta
    37621 caagtgaaaa gtctaaagga cctagtatct taagtattct ccactccttt tctgacttga
    37681 catcagaagg aatattatta tttaaacata caacacttaa ttcatcatca gttctagtta
    37741 tagagtaaaa cttctctgta tctatccatg ttggtatttt actgtcatta tttaatctac
    37801 atactgcata ctcttctacc aataatttta atttcataat gtatatttcc tccaatctta
    37861 tttgtttact taagattata cattaaaagt tacataaaat aaaacatata aagtaaaaaa
    37921 ggttcactat agtgtcctat ttctatagcc aacctttaaa acttaattaa attctaataa
    37981 agagatatat tatctaggtt caattataag tttaatggct gttttcttat caccttcgat
    38041 ttctatatca gtaaatgcgg gaatgcaaac taaatccatt ccactaggtg caacaaaacc
    38101 tcttgctatt gcaattgatt ttatcgcttg atttagagct ccagctccta tagcttgtat
    38161 ttctgcaacg cctcgttctc ttagtactcc agccaaggct ccagctacag aattaggatt
    38221 agattttgat gaaactttta gtacctccat ttcaacatct ccttgttaat ttgttaaagt
    38281 atccattacc taaagtacta aatcataatt gccatttact aattacaatc atcatttaaa
    38341 gtatactttt ataaaaatat acttctataa tcgttttaag aaaaccttta ttttttttaa
    38401 ccattttatt atgaaaaaac tacaaatttc tttatattct ataagcattt tccaatattt
    38461 ctaaattttt tatatctttg agctataatt tcctctttat ccatatcttt gtaatgattt
    38521 aatctttcta aaatgtaagc ttttatttct tttgaaacag cttctacatc tttttgtgct
    38581 cctccaagag gttcttttat aatcttatct attattttta aatcatataa atcattactt
    38641 gtaagcttca taacatcaca agcttcttta gctttagatg aatctttaaa tagaatacta
    38701 gaaagccctt ctggagaaat cacagaataa actgaatgtt ctaacataca tacatcattt
    38761 cctactccga tacctaaagc tcctccacta ccaccttcac caattacaaa agtgattact
    38821 ggaacagaaa gtttactcat ttcaagtaag tttcttgcaa tagcttctcc ttgtcctctt
    38881 tcttctgctt ctagaccaca aaaagctcct gatgtatcaa taaacgttat tataggtcta
    38941 ttaaattttt cagcttgttt cataagtctt aatgcttttc tgtatccttc tggatgaggc
    39001 attccaaaat ttctttttat attttctttt gtatctcttc ctttttggtg tccaactata
    39061 gtaacattaa actttcctat ctgaccaatt cctccaacca tagaagggtc atctttaaaa
    39121 agcctatctc catgaagttc taaaaaatta gaacaaatat gttctatgta ttccaatgtc
    39181 gtaggtctct ttatatctct acttagtgtt accttttcat atgctgatag atgtgaaaaa
    39241 gcatcttcct taagcttttc caatttctca ttaagtgaat ttattttatc acttaaatct
    39301 atattatttg ccttagaaat agttattaat tgtttaatat cattttctaa gacttttatt
    39361 ttttcactat tattttcaat caaaacagtt cctcctttat gccctatttc ttgtgcatag
    39421 caagaatttg atataatact tccttcattt ttcttctatc tactatcatg tcaataaaac
    39481 ctttttcaag taaaaactca gaagtttgaa atccttcagg aagtttttga tttattgttt
    39541 gctctattac tcttggacct gcaaaaccta tcaacgtatt tggctcagaa attataatat
    39601 caccaagcat agcaaaacta gcagttactc ctccagtagt agggtcagtt agaactgata
    39661 tatatggcaa tgatttttct tcaagcttag aaagtgcttg agaagtcttt gccatctgca
    39721 taagagatac cataccttct tgcattctag ctcctcctga agcagaacaa ataattatag
    39781 gtaaattatt ttcagcagca tactctattg aataagttat tttttcccca acaatagaac
    39841 ccatacttcc catcataaaa tcaggattca ttacacaaat aactgtttta attccattta
    39901 ttcttccata acctgtgaca acagcttctg actcttttgt tttttcctta taagagtcta
    39961 ctttttcttt gtatttagga aaatttagtg gattttgaaa ttctacatca gaattaaact
    40021 ccataaaagt tcctttatca atcaataaat ttattctttt tcttgctctt aagccataat
    40081 gtcttgaaca ttttggacat acaaatgaat tttcttctat gtcctttcta aatacatgac
    40141 tatcacaacc tttgcaatag gtccaaaatt tatcatctac actattcttt ttaaagttgt
    40201 catctaaaga aatcgtaaca tacttagatt cttttgatga taaaaatttt tttatcataa
    40261 tctatttact ccttataatg tagcaaattc tttcttcata aagacatctt ctataaattt
    40321 ggtatgatga gtatcttctc taaactcctc acttgttaca agtgcctttt gaaattctac
    40381 atttgtatta ataccttcta caataatttc gtctagagct ctatatattc tacttataca
    40441 ttcttctcta gtttcagccc aacatattaa cttacctatc atagaatcat ataaaggtgg
    40501 tatagtatat cctgcatata caaaagtatc aaatctaaca ccaaaacctc caggtaaatt
    40561 taatgattct atcttacctg gtgatggagc aaaattcttt gatgaatctt ctgcatttat
    40621 tctacattca atagcatgac ctctaaaagt aatatcttct tgtttaaaag gaattttatc
    40681 cccattagct atagatattt gaagttttat aaggtcaaga tttgttacca tctctgtaac
    40741 tggatgttca acttgtattc ttgtattcat ctctataaaa taaaagtttt tatctttgtc
    40801 aactataaac tcaatagtac ctgcaccgat ataacctact ccttttacta tatctactgc
    40861 aattttatga agtttttgtc tttcttcatc tgaaaggtat ggacttaaag attcttctat
    40921 tactttttga tttcgccttt gcatagaaca atctctatca cctaaatgta ttgcatttga
    40981 atgtttatct ccaaatactt gtacttctat atgtctagga ttttctataa acttttccat
    41041 atataaatca ctattagaaa atgctgctag agcttctgaa cttgccatat caaaatttga
    41101 aaaaagttct tcttcttttc taacgattct catacctttt ccaccgcctc cacttgaggc
    41161 ttttatcata acaggatatc caatttctct tgcaacttct aaagcttctt ccttagtttt
    41221 caaaacagat tctgaaccag gaacaacagg gatattcaat tccatcatag tttctcttgc
    41281 tctagattta tctcccatca aaatcatttg ttctcttgtt ggacctataa aaataatatt
    41341 attatcttca cattgctttg caaattcagg attctctgat aaaaatccaa agcctggatg
    41401 aatagcatca cactttaatt taagagcaag atagattata ttttctatat tattataact
    41461 cttacttata ttatttggtc ctatacaaat agattcatca gctatatatc tatgaaaaca
    41521 atctttatct atttcagaat agatagcaac agtttttata cctagttctt tacatgttct
    41581 gatgattcta actgctatat cgcctctatt tgcaactagt atttttttta tcaacttaaa
    41641 tacctcctac tacaatggtt ttatcttaaa taaaggttga ttatattcta ctagttcttc
    41701 attactaact aatacttcaa ttatttcacc tttaatttca cttgttatct cattcataag
    41761 cttcattgct tctaatatac ataaagtgtc gccttcttca actacatcgc caactttaac
    41821 aaagctatct gcatctggac ttggagaatc atagaatgtt cccatcaaag gagctactac
    41881 tactgataga ttctcattag atgtgacagg tgtatcgttt acaactggct tttctaaaga
    41941 aagatccact actgattctt gttgtacact taaaacaggt gaacttgtag attgagcttt
    42001 tttagatact tctaatctta aatcgctact ttcaagtttt acatattcta agttagttga
    42061 gtctatggcc tttaataatt ccttaatttc attgatgttc attttgttac ccccttgtat
    42121 tattacctgg tgctaatatt atatcacaaa aaacaaattt ataaaagaaa aagtgctgac
    42181 tagagaatca acacatcaat atatctttta attttaaatt aacaaccagt aacttatatt
    42241 tgttttaatt ttccattatt aatataaatt ataagtataa aatgaataaa attcaatatt
    42301 ttttgcaaaa tacaagagaa tacaaattaa tacctcggga atttttaaga caaataccaa
    42361 tattatgcaa tttagacttc gctttctttc aaattagtat cattttcttt atttttacat
    42421 aggatgtact ttaatttagc tatcaaaaca ttgctatata ggttaaaagt tattagaatt
    42481 gcaggaatta taaagtaaac tctagcacct ataaaaccaa aaactactgt aataagtatt
    42541 aatcttttat ttaaagtaaa aaaaggtata ttaaaaatac ttttgtcgga tgtttctgga
    42601 gtataagaat atataactcc aaaaatcaaa gtaagcatac aaagtggaag tagtgtataa
    42661 cttgaaatta ttcccagaaa tcctatactt tcaaaatatt tgctagcact atttgtataa
    42721 acaaacatgt atccatttaa atatgcgcat atacatgata taatgccaaa agttccccct
    42781 aaggattgag tgtaccaatt aaaaaattta gattccatat acctcacctc ctaaaactgt
    42841 atatataatg atatgcattt aaatagtaaa atatatcttt atatgtttct gaataaaatt
    42901 ttgttaattt cattaattta tgtttaagaa atttgaagta tagtgtagta tatattaatg
    42961 tagatgaagt tttatagtac ttatttcata gtgcttaatc aagttatctt attatggatt
    43021 caaaagttgt ttgtagggtt ttatattttg ttgagctgaa aaatttatta taaatgaagg
    43081 gatgttttcg ctttggtaga tacattagaa tttggtctta aaattttatt ttttatatta
    43141 tcaataattt ggatgggtaa aataatgatt ttaagaactg ataagcaaat agtaatcaat
    43201 cctttgctta ttggtatatc tgcagtcctt gtgatgttgc atacctcaca gagtaacatt
    43261 gaattttttg gattagatgt ccaatatata agaatagttt tgtatataat atattcactg
    43321 ataattttaa taggaatatg ggctactaac agaagaaatg gaatttttta gataatctat
    43381 ttctataaaa tttaaaggtt gctagtaaca aatcactaat attagcgttc tgttactaac
    43441 aacctttatt ttgattatac acttaaattg aaaatagaat gattgaataa gttgacagat
    43501 tattttacat tgacagtaat tagaacttct tgagatgtat ttaaatcatt tttgtcgctt
    43561 agtataactt ttaccactgc ttgacctgtt ttattacctt taattatcat atcttcacat
    43621 gaaagtacgc tcttatcact tacagataca ataaaattta aatcttttgg aaggttatca
    43681 gtaacttccc agtatttata ataactatca attttcttcg taattatttt tctcaaatca
    43741 atactttcac cttttgctat atcaacatta tgatatttag agtccagttt atactgatta
    43801 tcttttgtat caataaaatt taaatcgcaa tttacatcca caccattatg agaaagagaa
    43861 tttactacat cgtcatcaat caaataatta ttggcaagat ttattgaatc catatctttt
    43921 agacttaaag cttccttagg aacctctttt atattattat tccaaaaaat aaaattgtct
    43981 acattttcaa gatatgatat tccttttaaa tttgaaatgc tctcaccagt tgcataaaat
    44041 tctccatcta aagcctttat attgcttata gtcatctcat ctgggtttat atatcttttt
    44101 acaactgctc ttaaatttgc atcaggaaaa atatctttaa gttgattttc gctcaaaacc
    44161 ttatcatttg aatttattgg acttaaagct gctgcagaaa taataaatgg tattaaatta
    44221 gctaaattca tagtaccctc ccacataaat tttttattat aataatttaa tttctatgag
    44281 agggttctgt ttccttgtta tatataccta ctttcgtaca ctttattaat ataaattaaa
    44341 ataaatttct actattaaac ttataaacat attactagtt acgtttttta gcttcacatc
    44401 taaatattcg cataccttgt gacataaatt tgtcttcata ctctgttgta acattatttt
    44461 catactcact atttcctaaa tcaagagaaa tattctttaa tagccaatta tttgcagcaa
    44521 tttcatttaa actaaactcg aataattttt cattatctgt tttaaagtga atttcgccat
    44581 catcttccaa aaccctattg tacatttcta aaaatccaga atgagtgagt cttcttttac
    44641 tccatctatt tttaggccat gggtcacaga aatttatata aattctcgat aattctttag
    44701 cttcaaagta atccaaaata ttgcttacat ctccccataa aaatagtata ttattcaaat
    44761 tagaagcatc tgctttttca acagccttta aaagaacttc ttccttaagt tccatggcaa
    44821 tataatttat gtcagggttc tgcttagcta aagttgttat aaacttacct tttccagtcc
    44881 caaattcaac atgtattgga ttatcatttc taaactttaa attccacttg ccttttaatt
    44941 tgtctatatc gtctcttaaa acatattttg tataacttaa aagcttttca tctgcacctt
    45001 tttttcgtct tcttctcaca ataattctcc ttacatataa aaaattagta aaatacattt
    45061 ttattataca ttatctcacc aaaaaataaa aagaactctc ttaaaataga aatttatttc
    45121 tataaagaga gttctaaact tactaaaaac ttaatcttag tggcaccctg aacaaccaga
    45181 gcatcctcct ccaccttgat ctttcatatt ttcaggaata actctaaatc caaatcctgt
    45241 atcttctatt attatatctc catactgact atattcatca gagctcatta caaattgtaa
    45301 ttctccaact tcataagtta agtcatcttc ttttttctca tctaaagcta atccaaaaga
    45361 aggacctcca caaccaacac ctgcaaagta tactcttata ttattaggtt tatcttgatt
    45421 gtcttttaag atacttttta aagtatcaat agctgtttct ggtaaagtaa ttttcatcaa
    45481 atcattccct ttcaaatatt ttattaaaac aatatctatt atatacccat acaaggtaca
    45541 taatcaatta gtttttgcat attttactaa aacttctacc taatattacc taaggcttta
    45601 aaatatttta tataatattt tattacctta aataaatacc ctatcataaa cttagtaaac
    45661 aaataaaatt attattctaa aaaatataat aattttattt gttgttttaa tattataaca
    45721 catttgataa tgtccaattc atatatgcaa aatttatata ctttaaaata tctaagaaat
    45781 tattcaataa aaaaatacta ttttttaaaa attatcatta ttgataaagc tctactattt
    45841 atatttttta gtgtattcat gtataataag taaaagcaca acggtatata ctgttgtgct
    45901 tttttgtaat taataaacaa tattttggtc tataacaatg aaaaatggct actttccata
    45961 attgatttca tctgacataa gcaaaaaggg tgtccagctg ggtcaatcat aactctccag
    46021 tcatcagtaa attgctcctc tgcgattgta gctccacaat gaattgcata ttgaactgct
    46081 tcttctaaat cattaacagc gaaatccata tgagccattt gttgttgaga ttcaggtttt
    46141 tctggttcta ttatgcccca agcctttgtt ttttgcaata taaagaaaaa attatatatt
    46201 ttaatatttt ataattgttg aaattgtgta ataaattcaa ctggatacat agtgcgtttt
    46261 gaaatttctt ctaaagctaa accttgtttt aaaagtctct ttatgacgct ttccatactt
    46321 tctgaaattt ctataatatt tttatcaaaa tcataaaacc taaaagttct ttgaccccat
    46381 gggtattctt ttatataatg caaaaattca atatttccta ttctatttat cttactttcc
    46441 cattgtttga tgtcattaac ctcaaaatac aactgaaagt tatttgattg ttgatatatt
    46501 ggtaaatcat atccaattat agctttataa ttactttgta atccaaatcc attttcaaat
    46561 gatacatgtt ctcctaaatc taatgtgatt ttttgctcca taacatcttc ataaaacttt
    46621 tttgatttat ttatgtcttt tacaattagc aatactcctc caaatttcat cttatcacta
    46681 tcctttcttt gttataagta ttataactta aaattttgca atttcactgt aaaaatcaga
    46741 catattagct cggtattttt gaggagttat tccacagaca attttaaaat ctttaataaa
    46801 atgtggtata tcatagaatc ctaattcatt acatatagac atcaatgaag ttttattatt
    46861 gtttagaagt tttatagatt tattaatacg taccaaacga gaaaatgact tcatactcaa
    46921 ccctaggtac tgattaaaga gtctgtttaa atgcctagaa ctataaaata cttttttaga
    46981 aatttcttgt gaagatatat ttccagagtt ttgaataatc aactgaattg ccaaaataaa
    47041 ctcatatgag tattcaattt taatattaga aatcaataat tcttccaact ttaaaatcaa
    47101 tttatctata gataaagatt cattaaatat ttttttaatt tctaaatcta atgaagtatt
    47161 aattatagaa aatggaacaa ctttatcaat aagttcactt tgctgtatac ctataagcgg
    47221 gaaaaaacca gcaggttgaa attctataat tagtataaca tcacatctat tagcaatatt
    47281 tcctactgtt tttggtttag tagttggacc aaataataga ctatgtaacc ctgtggcatc
    47341 ataaaaaaac accaaagtta cacttccatg aggaataatc gtgtaattat cagaaattat
    47401 tgtttgattt ggaaacgata tagtaaaatt cgatatccaa tttcttaatt gtatacaagg
    47461 caagagataa acaaaattgt cttcacaaac tataagtgac ctatttttat ttataaaatg
    47521 aatactttct ttttttaaca tatattatat cctgtcctat cgtgaatatt tattaaagta
    47581 agaagaatcc atattatctc tatatatcat taactgcttt taataataga gatagtatga
    47641 atactcatta gatatttaat aaacaaataa aattaaaata atcaataaaa aatatagtac
    47701 ttttatctgt tattttaata ttatagcaca tttatagtat ttaacttata tccactttac
    47761 atatgtctaa tttatatagt taaaaatgct tatctcaaat acaataatta gtccttatac
    47821 aattaaacca tctgaaactg taatagtacg actactactt ttggctgctt ctggtgagtg
    47881 agttaccata attatagttt gtccattgtc tctgtttatt ttattcagta aatctattat
    47941 ttctatccct gttttactat ctaaatttcc agtaggctca tcagcaaata aaatctctgg
    48001 ttttccaatt aaagctcgag ctatagcaac acgttgttgc tgaccaccag ataactctcg
    48061 tggtgtatgt ttacgtctat cagttaaacc aactatatct aagatttcat ctaattgatt
    48121 tttataatct tttaaatttt taccatctaa taacaaagga agcattatat tttcctccac
    48181 atttaaattt ggtattaagt tataaaattg aaacacgaat cctatatttc tacgacgtat
    48241 tatgctcatt ttctcatcat taaaatgtga tatatcagct ccattcatat acacttttcc
    48301 gctcgttgga gtatctaaac cacctaaaat atataaaaga gtacttttac cagaaccaga
    48361 ttgacccatg atagaaacaa attcaccttt cattacttgt aaagatacct cttttaacac
    48421 tcgagttgtt gtatttccaa ttttatattc tttgataata ttttttgctt ctacagctaa
    48481 actattatgt gtaattttca tattaacctc cataattatt caaacttaat ttcttctatc
    48541 agtttcattt tcttcccttt tataataggc actattgaac ctattaaagt tactataatt
    48601 cccaataacc caacaataat aaatgtttta aaatctaaat ctggtttcat tgaaattttt
    48661 ggtcctgcaa ctataaagat agtttgaatc tcaagtatag atatcacaat accaataaca
    48721 gctccaagta aacctgaagt aaacccttca atcaatgtta cttttatatt ttgtttatca
    48781 cttagtccta tagatttata catagctata gaacgtcttt tttgaatata attaatcagt
    48841 agattattaa taatacctac tgtagcaaga agaaaaatga aataggtcat cttattcata
    48901 ggagacaaaa aactacttat agtatttaaa gaatcattat taaattcttc aactgtacga
    48961 ctccaattat atgtatctcc aaataaatat cttatctgaa tcataacagc atctggattg
    49021 actgctgtat atactaaaaa accataatta gttttatcaa aatcattaac tgcataatgt
    49081 gatggtataa cagcttctac atcatttgca cgggatttaa aactacctac tattttataa
    49141 gaaaaatcat acttatcatt agatagagtt attgtatctc ctatagataa gcctactttt
    49201 tttagagtat cttcattcaa aataacagaa cgtttatcat taaaagcttc tattacttgt
    49261 ttttttatct caaaatttgt ataattgatt ccaaacatag agttatatag ttttatatta
    49321 tctgtaccct ctagtcttga taatgttaca ccattaccag aaatctcatt attcataaca
    49381 taaagaggta atattttttt aattccatcc atatgtctaa catcttcaat aaactcttca
    49441 ttcatctttc catctgcaaa accttgtaat tctgcgtcac gaaacacatc tgttatataa
    49501 gttttgacaa agttaccaac aacacttatt gcaataactg cagaaatact tataaatagt
    49561 aaagtgatat tctgtattat atttttgtta tttttcatat ttctagcagc taatttaccc
    49621 tcattcccta aaatattttt ataaacaaac tcaaaaacta tagacatgat atcagtaata
    49681 agaggaatca acacaatagt agctacaatt aatcccagta atgaaaatcc accagctaga
    49741 tacaatgtat tttcagggga tattcttgga agtaaaatag ataaaataaa cattatactt
    49801 cctataaaaa gtatagaacg atttgaaaca ttcttttctt ctactgttcc tagtacaata
    49861 ttttttatcg gcaaatggct agctttttta acaggtatat atgcactaaa tgaagaaacg
    49921 attattgcta ctataacaga tataatcact ccaatgggtg atattactac tggaattgat
    49981 attccttgct cgagagaatt tcctaaccca tgaagcatta aatttaaaac aactacacca
    50041 ataggaatag caattaatcc tcctatactt ccgtataata tactttcaag catcaatata
    50101 cgagttacag ttttttcatt ggcaccaata cttctaaatg ttccaataaa aggaagacgt
    50161 tctaatgtaa taaccttata actgctgtat attataaata tactaagggt taatgcaaaa
    50221 aaacttatta aaaagaaagg cattgtcttt tgtctagcat ctgaaattat cttagtttca
    50281 tttatagtat ttgataccat atatttttca gtagaaagtt ctttggataa tttatttact
    50341 agattttctg taatttcttc ttctgactct ataagaattc ttgtatatcc actgccttta
    50401 tttataattt ttgatagagt ctctttgggt agcagtgcat ttacacctct tgtgttcctc
    50461 aaaaatactg tatcataaga tgcaatatca ctaacttgaa aagtataaga ctttccataa
    50521 atctgcaaag taatagaatc accttttttt attttatatt ttgatgtaaa gcgatttgga
    50581 agaataattt tatcaccaga aaaatcagta atactatcgc cattttctaa tcgtggcttg
    50641 ttgattttat ttagttgact taagtctgct gatataagac taaattcttc atagtatccc
    50701 cctttattat aaatagcaga gctttccaat acaccaacct ttgattttat agcatttaaa
    50761 tcaggtatgt cttctaaatt ggttaatata tctggatttt tactttggac agatatagtc
    50821 gctgtaccat acataccttt tgccattttt ctttgtgcac tttcataaga taatccaatt
    50881 gagaatgaaa caaaaagtaa aactgttgat aaaactatgg acaataacat aactgctgtt
    50941 ctaatttttc gttctttaat atttgtgaaa atatacttta atataatttt caaatttaca
    51001 ccttctttcc ttatctaaga tatttcaatc taatattttt atactttaat ctaaattaaa
    51061 tctctaatag actcctccat acttttatca ttctatttat aatattttta atcaaatcac
    51121 cccttaaata aaaaagattg ataaactact atataaatat aataatctat caaccttaat
    51181 atatttttta tttaacctta attaacctta attaaatagg aaaggtgata taaaatgagc
    51241 tacctaatcc aggtatactt tcaacagata tattccctcc atgaacttca ataatttgct
    51301 tcgttattgc tagtcctaaa ccagttcctt ctattttttg ttttgtattg cttcctctat
    51361 aataacgatt aaacaaattt gatgcttctt ctcttgacat cccttttcca ttatcagata
    51421 taatgatttc aattctttca tttaatgtta tatgtacaca aactttagta tttttatctc
    51481 catatgtaaa agcattgaca ataagattac taaaagctcg ttttaatagt gtacaatcaa
    51541 aatcaaagtt aatattatct atattactct taaattcaac tatatttgat tcatattctg
    51601 gataatttaa aatatcaatg gataattctt tcaaaaatct tactaaatca taattatttt
    51661 tatttaaagg gattattcca ttttttaatt gataggttaa ttttaaatcg tttataagtg
    51721 tatttgtata ttctatgttc tttaacatga ttgaagcata tttatgtact ttttcaggtg
    51781 aataattagt actactatct gtaagaagct ctgcataccc ttttattggt gaaagtggag
    51841 tttttaaatc atgagttata tttgaaatcc actcttctct cataatatca gttttatttt
    51901 gtatctcatc acttttatga atttcttcat ttaaaatatt taaactatta tatatatcag
    51961 caaaaacacc tttaatatta actggaagat agcttcgttt tgaaatatcg ctaacagcag
    52021 atgtaatatt tgatatgcac tttgttaccc agtaaccata agcaattcca gaaaccaaaa
    52081 ttattaaaaa tataatccct atgattgaaa atataattga cttaccacct ataaatttac
    52141 ctccatcaaa aaacatattc actttagata tatttaatgg aaaatatata atataaatat
    52201 agtcattttt attattttta attgtattaa agtatacagt tccattactt gaattatttt
    52261 ggttagctaa tgctaataat tcagaattag aataataatc tttatgctct tttggttcta
    52321 aaaacccata aactctattt ccactagaat ctaaaatttg caaccacaat tgattttctc
    52381 gaagtttttt taatccagac tgttttactt gtggcttatt atctataaat acgatttgtt
    52441 cattaaagtt ttctgtaaat tttttcggcc agtcactacg aataaattcc ccatttggtt
    52501 tctgaatagt aataagtgat aagaaaatac ctattactgt caggattaag caaataaaaa
    52561 tcatgaaaaa aataatgtat gaatgaaata ctgttttata actaggttta tgcatttaat
    52621 caactctttt cttaaacttt tattttgatt gttgcttata taaaatagac aataattatt
    52681 gatatgtaaa aatttattta aaaatacaac tatctacata aattatattt atataattat
    52741 atgttatcaa gctgtctgtt gtatttaata aatcattttg ataacatata aaagtaagat
    52801 aaatttttcc atcaaatacc ttataattat acacaaaatc tctatatacg ttaaacagta
    52861 tagagaaaat tttcatagaa ccatctttat aggggatact ttataaaaga ataaaaaaat
    52921 tataatatat aaaaaacttc ataggagtgt aacaacatca gtaaagatat gaaaacacta
    52981 tataaaaatt caaaaatatt aagaataatg aaatacttga aattgcttat atcaagaaat
    53041 tttatataat ataaactggt caaatatgtt ataatattaa attgtgacaa gttcatggag
    53101 gtgtttatat gaaaaaacaa aagtcgccaa ttttacttga aatgcttgga ctattttttg
    53161 gttgtatatc aatgagtatt ggtataaata tgtttttaaa accacataca attgctcctg
    53221 gaggacttag tggtctatca ttagtactaa acaaggttac aggacttcca gtatcagcta
    53281 tcatgttaat tataggtgtc ccattagtaa tacttgcttt tagaattatg ggtacaaaaa
    53341 attcattaaa aactttattt ggaacagttg tattttcagc tatagttcaa ttaacagacc
    53401 cattatcaaa actaagattt actaatgact tattattgtc ttctattgca ggaggaatcc
    53461 tagttggtat aggtttagga ataatgttta aatcagatgc ttctactgga ggaacagact
    53521 taattgcact catacttagt aagaaattcc caggaataaa agctacaaaa ttcatgtcat
    53581 gcctagatgg aatggttgtt atatcttctg gtatagtaaa tcgtagttta gaaactgctc
    53641 tttactctgg tatagcactt tgtgtattaa taaaaatagc agatatgata atggaaggat
    53701 ttgaccattc aaaagcattt tttattatct ctgatgagcc tgaaagttta agacaagcta
    53761 taactgaaga acttgataga ggtcttacta ttcttgatgg taaaggtgga tacactagag
    53821 aaaataaaga agttctatta gtcgtagttt ctaaaaaaca agaactttat ctaaagagat
    53881 tagttaaaag aactgaccct actgcatttg ttattgttac agatgtacat gaggttcttg
    53941 gagaaggatt taaaaattta gagaactaat aaaaattaat attttaagta tatatactat
    54001 tttaattaaa atacgattta ttcaaaaaga gtgtctcata aactttttag ttcatgagac
    54061 actctttttt gtataaaatc aaatgcattt tcagtatttt aacaataaaa acaggattat
    54121 ctatattttg aggcaaccac tttattgaaa ttttatttag aaaacaatca ttactaaata
    54181 accagcatag atattaaatg attatatcta ttgttttttc aattcatatt gataacaagg
    54241 aacatttttt acagtatttc cagtatgaat ttttttgata tactttcctg tacatttaaa
    54301 tcctaataaa tctaatgatt ttgtagaatt ttggttttct tcataggtta ttgcaattat
    54361 tttatttaag tttagttctc taaatccata ctgtattact ctttttgtta tctcagtagc
    54421 aaaatcatgt ccccaatagc ttggatttat acatatacct atttctgctt ctaatgcttt
    54481 aggatttata ttattaaacc ccatatttcc aataacttta ttgtctcttt tatatactat
    54541 agcaaagtgg ccaattttcc cttttttata tggatttaga aaaaatgatt ttataaactt
    54601 tcttgtatct tctaaagatt tatgctcact aaatggtaaa tgttttacta ctattttatt
    54661 tttataacag tcaaaaaaat cttcaacatc atctaatgat gcaggtctta gtatacaact
    54721 tctagtttct aaggttttca tttgaggata ttcagaatca gacatttcta atcccccttt
    54781 atacattaat ctaaatatac tgttcatatt taaaatacga tattaattat ataaatgttc
    54841 tcaaattaac cttattttta tttttaataa aaactaatta ctatatgaat ctttcaaatt
    54901 tacaaattta tctctatttt tatattaaat tacttgtgaa atatgtattc taaattatat
    54961 attattagat atcatgctta aaaattcttt ggttgctaag gataaagata tatcttttaa
    55021 atggcaataa cctatatttc tcttaggtat tggctctttt atatctaatt taaacaattt
    55081 ctcattttcc aaataatcta tgctaaattc ttctataaca caagacactc caagatttat
    55141 atacgcaaat tctaaaagta attcatgaga acccaattct atatccgggt ttagttttat
    55201 accttttgat aaaaaatatt catttacata aagtcttgaa tttgctttat tttctagcat
    55261 tattaaaggc aatgtgttta attcttccaa tgatattttc ctacctttgt attctatgta
    55321 atcatttgca catacaaata tatcatgtat ttcaatacat tcaacaatat ttagtgtatc
    55381 atcttctatt ggcatgttta taattgctat atctatattc ccatctttga gtaaagatat
    55441 aagttctcta ctcgttctat ttattgtaga tacatgtata tgtggatact tcttatgaaa
    55501 aatttctaaa tattttaaca agaaaaaacg tgcagctgta tctcctactc ctattttcag
    55561 agaaccgtat tctaattttt taaatttatt tattctatct tctcctgatg atattaactt
    55621 taatgcagta gtgacatgtt cacttagaat tttcccctct ggagttaatt ttactccctt
    55681 attgtttcta taaaataata aagtatctaa ttgttcttct aattgcttta ttgactggct
    55741 tacagctggc tgtgacataa acaattcctt agcagcaaga gaaaaactct tattatttac
    55801 aactgcatta aaaaccttat aaagttcaag ttttatattc atatataatt actccttatg
    55861 tcaaatatta gtattattta ttttacttat aattatattt gaattataat atacatggta
    55921 ctaatatgac aatattaatt ctttaggagg attttagata atggatagat tagttggaac
    55981 tgtttcaaga ggggttagag cacctattat aagacaagga gatgacttag ttaaaatagt
    56041 tgttgattct gttttaaatg cgtcaaaaag tgaaaacttt gaagttaggg acaaagatgt
    56101 aattgccgtt acagaagctg ttgtagctag agcacaggga aattatgctc acgttgacaa
    56161 tattgcaaaa gatgtaaaag ataaatttgg agatgatact gttggggtta tattcccaat
    56221 tttaagtaga aatcgttttg ctatatgttt aaaaggaatt gcaaaaggat gtagaaaagt
    56281 cgtattaatg ttaagctacc cttctgatga agttggaaat cacttaataa gtattgatga
    56341 acttgatgat aagggaataa atccttggtc agatgtttta acagaagaaa aatacagaga
    56401 actatttgga tataacaagc atacatttac tggtgtagat tatgttgatt attataagaa
    56461 tttaatcaag gattgtggtg cagaggtaga aatagtattt gcaaacaatc caaaaactat
    56521 tcttaactat acaacaagta ttttaacttg tgatatacat acaagacaaa gaacaaagag
    56581 aattttaaga caaaatggag ctaaaaaagt atattcactt gatgatataa tgacagcaag
    56641 tgtagatggt agtggttaca atgaccagta tggactttta ggttcaaaca aagctacaga
    56701 agaaacagta aaattattcc ctataaattg tgatgaagtt gtaaacaaaa tccaaggtaa
    56761 tataaaagaa ataacaggga aagatgtaga agtaatggtt tatggagatg gagcttttaa
    56821 agaccctgta ggtaaaatat gggaattagc tgacccagta gtatctcctg cttatacaaa
    56881 agggctagag ggaactccaa acgaagtaaa attaaaatac ttagcagata atgattttgc
    56941 tgacttatct ggtgatgagt taaaagaagc aatttcaaaa tacatagttg aaaaagataa
    57001 taaatctgat gatttaacag gaaacatggt ttctcaaggt actactccaa gaagattaac
    57061 agaccttata ggttctttag cagatttaac atctggaagt ggagataagg gtactcctat
    57121 tatttacata caaggatatt tcgataacta tacaaaatag tatgttttaa taagatttaa
    57181 attttttgga ttatatatat taacatgaaa atttattaaa acctcttaat agatatgact
    57241 tttcaagagt tatatctatt aagaggttta tttaatgttc acagataaga tatatttaaa
    57301 taatttaaac aagattgtca gaaagttata taatcttaaa aatttatata actctaattc
    57361 ttatttattt ctgaaataat atcactcttc aaaatttgtc ttactggaat aattacagca
    57421 actatactaa tagtgatatt taaaataatc atacctatgt atagaggtgt atttatttta
    57481 agaattggat ttatatataa gtatacacgt tttaccataa aataaatcat aaattgtcca
    57541 ataacacttc caattaccat tataatactt gcatagaatc catataaaaa accttctctt
    57601 atcatcataa gtaaaaactt attatccgta atacccatag ctcttaaaat tccaaactca
    57661 tgtcttcttg aaaaaattaa gtaacttact gtattgatta tatggaacaa acttattgca
    57721 agaagtacaa atacaatacc atatataaat aagagttttt gatttaagta ggtattattt
    57781 ttttcaatag caatggtata atctgttaca atacatcttt ttacatcact tacaacactt
    57841 tttatgttct cagacaattc ctcactgtta ctatcttctg tcttttttat acttactgaa
    57901 ttataatttt cgatatcaaa gttatttttc atttgcccat tcgtcataac tatatccata
    57961 ccataatcac caatgaaata tatgttattt gccatcacac gttttacagt agcagcaact
    58021 acaaattctt ttgttgtata atcattctta ttttcttctt taaatttaac aatttcatct
    58081 gttggtttca ttgtctttgg cactttaact tttattgtat ctcctggatt tatatcaact
    58141 gcatcataca tcccagttcc atccataggt agtctaacta taaccttatt atttttaacc
    58201 atatcatggg tattaatctc cccatctata atataagaat ttaatccttc taacatacca
    58261 ttgttataac cataaatatt tgtttttaaa agatagccac cttcattttg ctttgtacaa
    58321 ataccatcaa aaaaagtctt tatcctgtaa tctttttcaa gaggtttaaa gaaatttttc
    58381 caaaatagtt gttcttcttt aatttgcata gctccaaata aatatcttac tggatagact
    58441 tttgatattc cctcaacatt gtttaatctt gaaattttat cttttggtat acctacatca
    58501 aaatctgttg tttgcatagt tatttggtag tcagaattta aaccatcatc agctttcatt
    58561 gtaagttcat tgttattttt agtaagctgt atagagtaac tagaacatag aaatataatt
    58621 ccaccaagtg ataatgaaaa caaaattcca ataaacattc cctttttttg agtcatgtat
    58681 ttatgagata atacttttgt catgttagag tgttttacac tttctaatat tctctttttc
    58741 ttattagtaa tcttaaagtt tttcatagat tctatactag agtatttatt caactgatgt
    58801 acaacacgta cagcaattaa aattaacaac aataagataa ataaaaagcc taaataaata
    58861 gatttttcac ttataaaaaa tgctcctgga acaatatcac tactcaaaaa tatatgtgga
    58921 aattgttcat atattgtaga cgctactcca atacctaaga agcaacctat aggaaatcca
    58981 acaataaaaa gtaaaaataa ctctaaaaat agtagaaata aaagttgttt attattagcg
    59041 cctaatactt ctaaaacccc atattgtgat attctctgaa gtattgaaac atggaaaata
    59101 ctatatactg ctgctgcacc aaacactcca acaagcaata taattgcatt tgtatttagt
    59161 tctaaatttt ttaagaactc aaatatatta tatttttcta tattttttgg tggttttact
    59221 ccaaattcaa ctgaaagagg ccagtttata taagtttttt cttttgatat gttgaatttt
    59281 ttcataaatt tataattttg ctttttaata tttttatttt catcatattt tacataaact
    59341 atataagaat ccttttcttt aggctgaaaa taatcgttta caaatccctc cagagcagtt
    59401 tctgggtttg aaagacttga taaaatacca cataacttat agattttacc atctaaattg
    59461 atttctgttc caatttcttt gtttacattt aaattgttta gagaatatgt gtcaagtact
    59521 atctctccat ctttactagg aagagttcct tttaataatt ttctacctgt catatctaaa
    59581 tatgaagaat cagcatttaa aaattctata ataaaaggtt catctatctg atttttaggt
    59641 tttgtaacgc caagtctatc tacagtgtat tcctttgatt ttttattttc tttaatttta
    59701 ttaagttgtt ccttatctac tttatagaaa taatgataat ctccactatc ttcccttatc
    59761 ttttcaattc tacttttgtc tgcactatga actaaagaac caattcccgt caataatgct
    59821 actgatagta ctatgcttaa aactatagat atagattgtt ttttataatg ctttatatat
    59881 tgaattgaaa attttactag agacatcata gtacttcacc accagtattc accacaattc
    59941 catcttcaat atggataatt gagtcgcata cttgtgctat attttcattg tgtgttacca
    60001 taagtatcgt ttgatggaat tttgcactac tttcttttaa taaacatacc acttccattg
    60061 tagttttact atcgagattt cctgttggtt catctgctaa tataagcgca ggtttatttg
    60121 ccaaagctct agcaattgct accctctgtt gttgaccacc agatagttcg cttggaaatt
    60181 ttaaacgctt atcccaaatt cccaatgtct tcatcagcat ttcaatatat tcatggtcta
    60241 tatggtttcc tttatctaat gtaacaggaa gagctatatt atcataagtg tttaatacgg
    60301 gcattaaact gtagttttga aatataaatc ctatatttct tcttctaaac actgtcaaat
    60361 ctttttttcc tattttagat atgttctttc ctttaattat tacatcacct gaagttggat
    60421 tatctaatcc acctataata tttaacaatg tgctttttcc agaaccagaa gttccaacta
    60481 tagcagtaaa tgtatctcgt tcaatttcta tacttactcc atttaaggct tttactttag
    60541 tctcaccttt tccatagtgt tttactaaat tattcgtcac taatatactc atttaatttc
    60601 tcctttcaat acagatatat gttctataaa atattgtaag tgacgataat tacactcatc
    60661 ctacaaaatt agtttaaact cttacaattc tgtaagaaga tactaaaaca acatccactt
    60721 cctagtttag attctactat aatgtttcca ttttcttttt ctaaaattaa tcttgtaaga
    60781 tatagaccaa tccctgtgcc attttggttt tccacatttt tacttctgta aaatctttta
    60841 aaaatatcat ttagttctct actatcaata cctattccct catctttaat agtaatcttc
    60901 gtatatagtt ccatttttat tacagaaata gtaatcgtgc tatctgatgg tgagtatttt
    60961 attgcatttt ctaaaacatt tacaattgct tctatggtcc actttttatt atgaactaat
    61021 tttatgtctg aaaatggttc gagatttatc cttatatttt tagcttctgc tttattaaag
    61081 atagtactga tactttgaat aagagtatct ttaattagta gttcttctac ttcaaattct
    61141 ataactccat cctctaattt agtcatttta aataaggatt gtaacagcca gtcaatctta
    61201 aaagtttcat ttttcatctt ttgtaaaaac tccttcttct gtaatgtgga aatatttata
    61261 ttctccagaa gttcacaata aatggttata tttgaaagtg gagtttttaa ttgatgtgac
    61321 atatttgata ttaaaccttt aatcgcttct ttttctgact ttgactgttc tacctctatt
    61381 tctatcatat ccttaatttt ttttacttgg tgagaaattt ttgacgctct tgtatccttt
    61441 gtatctggat aagtaacttc tttaccttcc aatatttgat ttaacatcaa atttaattca
    61501 tcatatcttc tttgatttat tttagtagat actataaata taacaactgt acatattata
    61561 aaggctaata taaacatatt attctacctc attccataaa taacccattc cataagctgt
    61621 ttttatatat tttggattag atgggtcatc ctctactttt actctaagtc ttcttatatt
    61681 tacagataca atattatcat caacataatt ttcttcgctg tcccaaatat ggtgtaaaat
    61741 ttgttccttt aataatattt gacctttatt ttcaattaga taacttagaa gcttatattc
    61801 tacagagcta agttccaaac attctttatt tttatatact tttagtaact tttggtccaa
    61861 ttttattcca ttggaatata ttactttatt attcgatttt tttcttattg ctactttgac
    61921 tcttgccttt aatacagata aagaaaatgg ttttgtaata taatcatcaa gccctatttc
    61981 taatcctttt acttcatcaa tttctgagtc tcttgcagta agcattataa ttggtatatc
    62041 tgacttttcc cttattattt gacatacatc aaatccatct ccatctggaa gattgcagtc
    62101 taagattata aaatctatat ttttactatt aaatatattt aatccttctt gttttgtata
    62161 agccttaaat acattaaatc catcattctc aaatgcataa aaaagacctt catttaagtt
    62221 tatatcatct tcaataatta ataagttcaa ttttactctc ctttagattt tttagataaa
    62281 taattatttt cttgcattat catactaaaa atattttaat tttatttatt tcactaaaaa
    62341 gattgtattt aaatttgttt tcaaaataaa aacatcataa tcaagcatat agttatatat
    62401 ttcccaattt aattacgctt aaattgaaaa tataacttta ttcttatata attaaattat
    62461 acaacaataa agttatattt tttaaatata tttttactag ggggaataga attgaaaagg
    62521 gttgatgaga gaaatactat gtttgcaaga gcaaattaca aaaaagatag tactgcttat
    62581 aatgactatt ataagaaaaa tcctgacaaa aaagaaattg atgatagtat aagaaataga
    62641 ccaaatttat gtagtgaagg aacaatgact tacaatgagt taaactctcc aatggcaagt
    62701 agtgcattcg attttttatc tgatatcaaa tctttatgcg aaggaaaagt ttctgatact
    62761 aaagtagatg tagatgcaaa gtcaatgaca aaaaaaatta agggtcttgc aaagcagtat
    62821 ggagcttctg tagttggtat aactaaatta aaagactatc atatttatac aaataggggt
    62881 agacatgaag aaaattacgg tgaagaaatt aatctaactc ataagtatgc aattgtattt
    62941 ggatgtgaga tggataaaga aatgataaat agagctccaa tgatatgtga agttatagaa
    63001 acatcaaagt gctatgtgga tgcatctatc gtcggcatga ttttaagtta ctatataaga
    63061 aatttaggat atgatgctag aaatcatatg gatgctaatt atttagtaat gcctgttttt
    63121 atagctcgtg atgctggttt aggagatata ggaagaaatg ctatacttac gaataaagat
    63181 tatggctcta gacttagatt aggtgttgtt actacagata ttcctctttt agaagatgaa
    63241 tatgttgatt ttggactaga agatttttgt aaggtctgta aaaaatgctc ttttaactgc
    63301 ccttctcatt cgctttctaa tgatattaaa attggtgatg atggaaaata taattgggta
    63361 attgaacatg agacatgcta tattaaatgg agatatttag gtacagattg tggtatgtgt
    63421 atatctgctt gcccatttag ccaaaatctc gaaactataa agaatactac ttcatttaag
    63481 ggtaataatg agcttattca aaaagcttta gatgagtata cttcaaaatt tggtaaaaga
    63541 atatttatac ctggaaatcc atcttggttg aaataatttt atttaataaa gaatctgtac
    63601 tagaatttat cataggacag gttctttatt aaatatataa atttttaaat actttttctc
    63661 gtttataaca attcagcaat gtttttagtc tataattgac attataaaat attaaactaa
    63721 aaggagtaac tgtatggaaa aaatattagt agtagaagat gattctatat taaataaaac
    63781 tctatcatat aacctaattg aagatggata tataattact tcaaaattta cagctaaatc
    63841 tgcactgaag tctatttttg aatgtgaatt tgatttaata attttggata ttaatttacc
    63901 agataaaagt gggtttgaat tatgtaatga aataaaggaa aattacaata taccaataat
    63961 ttttttaact gctaatgata tggaatgtga tatgattaaa ggctatgaac ttggagcttt
    64021 ggattatata acaaaaccat ttaatatcaa tatatttaaa cagaaagtta aagctttttt
    64081 aaatcatctt acagtaaaaa caaaacaaga ttactatagg gatggatatc ttgaaattaa
    64141 cttttctgag ttatctgcca atataaatgg aaatcaaatt atatttacac cattagaata
    64201 tcgtacttta aaactgctta ctgaaaatcc taaaagtatt ttaacaagga aagtactttt
    64261 agaaaaactc tgggatatag atgctaactt tgtagatgaa catactttaa catctgttat
    64321 aagtaggatt agaagcaaaa ttgaaaaaga caatcttaag tatatcaaaa cggtatatgg
    64381 tatgggatat atgtggttag gtgaaagaaa tgaattttaa aaaattttct tttagttcta
    64441 tttatttaat aattgctgtt ggtataattt ttacagctat tttatttagt atctcaattt
    64501 atctaataac tgatgattta aaactaattg ctctattatt aatatataca atagtacttt
    64561 gtggatttat agcattaaca atatttttac ttcataaaaa aatagttata ttttgttcta
    64621 aaatatgtca cactttagat agtatgatga atagtgaaga caatattgaa attgaattag
    64681 aagaagaaac tattttatca cgtatcaatc acagattaat tagaatgtat gaagttattc
    64741 aagaaaatcg caatagtatt gctatagaga aagctgattt acaagaacta gtttctgata
    64801 tatctcatca aattaaaact cctattgcaa atttaaaaat gattaatact actctactaa
    64861 atcaaacatt taaaacagaa attcaaaagg attttttaat ggatatggaa aaccaattag
    64921 ataaattaga ttttttaatg caatctatgg taaaaacctc cagactagag acaggtataa
    64981 tcacactatc taaaaagaaa aattcaattt atgaaacaat tgctacagca cttagtggaa
    65041 ttttgtttga tgctgaaaaa aagaatattg aagttacagt tgattgtgac ccaaatttat
    65101 atataattca tgacaagaaa tggacttctg aagctatttt taatatatta gataatgctg
    65161 taaaatacac aaattctaat ggtaagatac atgtagctac agaatgttgg gttatgtata
    65221 caaaaataga tattattgat aatggaaaag gaatatcaga aagtcatcaa gcagaaatct
    65281 ttaaaagatt ttatcgtgaa gaagatgtcc atgacataga aggtattgga ataggtctct
    65341 atctttcaag aaaaattata tctcttcaag gtggctatat taaagttaca tcagatattg
    65401 gaaaagggtc gactttttct attttcttac ctaataaata aatttttaaa tatttcattt
    65461 gtaatgattc tgcaacattt tggttttata ctgtatttac aagatgttaa ggaggtatta
    65521 ttatgagtat tttacaagta attaatttaa agaaatatta tggacaaagt tcaaacatta
    65581 caaaagctct tgatggtgta actctatcta ttgaaaaagg cgaatttatt tctattgtag
    65641 gtacatctgg tagtggcaaa tccacattat taaatatgat gggaggatta gataatccta
    65701 catctggaaa ggttattata aagggtaagg aattatctac tatgactgat gaacagctta
    65761 caatctttag acgcagaaat ataggtttta tatttcaaaa ttataatctt gttcctttac
    65821 ttaatgtata tgaaaatatt atcttaccaa taggattgga tggagagacc atagataagg
    65881 attttataaa tgaaattata aatatgcttt ctcttgaaga aaaattatat gatatgccaa
    65941 gtaatctttc tggtggtcaa cagcaacgtg ttgctatagc tagagcactt gtaacaaaac
    66001 cagctattat actagctgat gaaccaacag gtaaccttga tagtagaact agttcagatg
    66061 tactgagttt acttaaagtg acaagtaaaa aattcaacca aacaattgta atgattacac
    66121 acaataatga aattgcacaa ctaactgata gaattattcg tattgaagat ggaaaaattg
    66181 ttaactagga ggtgtagtat atgtttagaa ataataatcg cacatttata agaaaaatag
    66241 ctttaaatga tttaaaaatt aataaactta aaacatatct ttcaggtatc attataatga
    66301 tttctacatg tttattatta acagtgacct tagtttcata taatgcctct gtagatttag
    66361 ttaatgcatc tccatatcat gctatatata aatctgtaga tgaaaaagca aaaaatatac
    66421 tatataaaga taaaaacttt agtggcgtag gaacttacaa attaattgga agtaataaaa
    66481 agacagattg tattatgtcg attgtttatg cagatgatac agcaattaaa cttatgaatt
    66541 ttcaaccatt gaaaggcaaa ctacctacaa ataaaaatga aattgctatt tcagaaaaat
    66601 atttacagga atttggttta gataaagata ttggagatag cattaaatta aattattatg
    66661 atgatattac gaataaagaa gttcaatgtg attttattat tgttggattt ctagaaaatt
    66721 attatcaaga taatgccaag caatactata cagtcgtttc aaatgattat tttaagaata
    66781 tagcttctac acctttacaa aataaaagta atacttttga cgagtcaaga cctgatactg
    66841 tagatgtatt agttaaacta tcagaagaaa atacagagaa agattcagct tcaattaaga
    66901 cacagttaaa gaaaattggt ttatctttag gtattaagaa atataatata tacttaaatg
    66961 ataactatat tgaatcaaat ttaattgatg gtgagcagat tattacagtt ttagtagttg
    67021 gaatagttgt tcttttttct agcgtttttg ttatatatag tattttttat atttcagttg
    67081 ttaattcagt tcagatgtat gctaagttga aatcgttagg tatgacttct tttcagttaa
    67141 aaaagattat ttctctacaa ggaaatattt tgtcaattat ttttattcca ttaggggtta
    67201 tagcttcttg tataattgct tacataattc aaccattagc atggcaaatg atagctgatt
    67261 tatttataat tttaatttta tcactggtaa tgtttttaac tgttagaatt tctttattta
    67321 aaccagctag aattatttct aaaatatctg ctattgaagc catgcaatat acagaaacta
    67381 aatttagaaa aaaagcaaaa aattttagtt atataaatat aaaaaatcta gcattaaaga
    67441 atatcgagtc aaatagaaaa aaaaatttga ttgcattaat atcgctaagc attagtggag
    67501 ttttatttat ttcaatcgct aatcttgcta attcaataga tttcaaaaaa caactatctc
    67561 aacaatttgt ctataacgaa gattatataa ttagcattaa gagtgataac ttatatgagc
    67621 atattacaga aatccaacaa aataatccac taacagattc tcttaagaat gaaattaaat
    67681 ctattcatgg agtaaaaaaa ttaattgaat ccaaatcaat taaaagtaat attatagaac
    67741 cttacatcaa agatagagac gaaaaacaat ttattactct aattaaaggt attacgcctg
    67801 aactttcaaa atcacttgaa gaatatattg tcagtggaaa aatagactat acacatttag
    67861 attcagatag tttaattata aataaatata gaacaaaata ttatggatta aatttaaaag
    67921 ttggagatac agttacattt aatatcttta gtggaaatga tattattaaa aagaaaatga
    67981 aaattatagg aatcattgac aattccaata caggaggtat gttttttgct tcagacaaaa
    68041 ctttagaatc tctaacacca tataatacaa atttagattt ttctatttta atagataaaa
    68101 agcattctaa agaagttgaa gaaaagttgt taagtataat tcagaaaaat tcaaatttaa
    68161 tgctttattc atatgaagat gattatagaa tgattactag agcatttcaa tatataatta
    68221 tagcttcata catttttgtt ggtttaattt cttgctttgg tatactaaat atgaccaata
    68281 ccctaataaa cagcgtttta attagaaaaa aagagtttgc attacttcaa gccgttggaa
    68341 tgacaagaaa gcaactgcga aatatgcttt atagagaagg tctaaacata agtatcaaag
    68401 ctatatgtac ttcaagtata ctaggttatt ttggttcaaa tctactttgc acttttataa
    68461 aagatgtaat tagattagac tttattaatt ttaaattttc tatatttact attttaattt
    68521 tttcattcgt attaattggt atacaagttt tagtgactga attacttgta agaaatatag
    68581 aaaaaaaatc acttacagaa cgcttacgtt ctcagtaaga atgtatataa aaaatagcca
    68641 ttttttatac aagttttaat atgatttttt aaaagctata gggatagaaa attttgactt
    68701 tacataattt tctatcccta tacttgtttt tattttatac agatacactt acttatatct
    68761 ccgagcaaca tcaccagaga cataaacaag catattcctt attttctaaa tatgtcaatt
    68821 gcatgacttg taacccctac taaatcttca cgttcacaag tagcaaggtg atattttaaa
    68881 tataatgcaa atgcatcatc atccatagag tctactgctt cacgcatata caaagccaaa
    68941 ccatctgatg cgacataatg cagtctagtt acattaaatg cagacatcaa atcatcaatg
    69001 ttttctttac gtacaagctc aaacaaatcc tttggttcag acttagcagc aaatgtctgt
    69061 ggatcaatca aacctttttc aatatattca gatacattaa tatttcctct atggaacccc
    69121 tcgtcaatga gacagccatc agatataaca tatgcagcaa aaaccacacc accaggtttt
    69181 gttacacgaa ttgcctcatg taaagcttgt tgtttatctt ctttgttata aagatgatat
    69241 agtggtccta acagtaacgt aatatcatat ttattatctg ggaaaacaga taaatccata
    69301 gcattaccct gagtaatgct tatattttca tttgattgag tatttttatg gaaaacctct
    69361 atattatgtt cgactaattc cactgcgtca acatcatatc cctgacgtgc cagtgtgtga
    69421 gaataacgac cagttgcagc gccaatttca agcacacaat cacctgattt tatgtactta
    69481 tcaatgtaat gcatagtagt gagaaattcc accattccat gttttaatgc aagtcgacta
    69541 tcttcatcat aagtattata aaagtcaatt aagtattgtt ttgtttccat aatttcacct
    69601 cttctatatt agttaataaa catcaaatag acaaattcca atctggtttt tcttgtctta
    69661 taaaagctgt taatatattt ttcaacattt tttcagcact atatctatct aatgttaatt
    69721 tttttgttgc tgttaagaca gctatgccat gagtataaag aaataaatct aaaaatatta
    69781 cttttgcaca ttccaaatct attccaatgc tttccgaaaa aagtcttgcc tttttttcat
    69841 tgtaaatttc tttataaaaa tcattcgcct ctttcatcat caaatctaaa tcatttataa
    69901 ataacaactt aaataaatac gtttcttctt gagcaaattc aatgtatgaa agcggaagca
    69961 gtaaataagg gcttacactt ttagaattac gataattaac aacatactga ttataatatt
    70021 catatgcaaa agcaagaaat tcatttttta attcattcat gttttcgtaa caagtaaaaa
    70081 ttggtcgagt ggaacactgt aatttacttg caatactcct cgcatttaca gcttcaaatc
    70141 ccacttctct tgtaatatcc aagactgtat tcaaaatcat ttcttttgtt atctttactt
    70201 taggtggcat atatgttcac ctctccatta aatttttata aaacacatat gttatataac
    70261 tatagtaaca tatcaagaaa ttatgtcaag aaaaagcttt gcattttttt gcaattccta
    70321 aaacttataa ataaaacatg agttgcaatt aatctattaa tagataacag caactcagat
    70381 tttcctttaa atactcttct ttttgtctaa tatttcatat acacaatctt ctattgaatt
    70441 aatatctttt tcttttcttt ttttagaatc aattaaaatg aaatacagta taaaacctac
    70501 agcaagtccc catgttccgc ctttagcagc aattacacct cccataagtc caatcaatcc
    70561 cttctcaaca cctgtattac atagctccat tgatagcttt gtacataaat atccttgaac
    70621 taaaagtgtt actgacaatg ctaatggtat aagaggtgta gcaatctgcg caattggata
    70681 aaaacagata aaaattgctg aaacccatac taatgtaccc atgccactaa aaacagactg
    70741 catggcttcc tttccaacct tgtacctttg agcaacactt cctgtaagtg tcgcagctaa
    70801 tggaccgcac attggtatat atggagaaaa gattgccata aaaatatttc ttatcccact
    70861 tataacatta gacctatttg aattgaaatc tatatattca tcttttctat tttcactttc
    70921 agaaagtact aagttttcac ctgttataaa atcaccaaag gcaattatgt atatcataaa
    70981 agccattggt atcccttgta taaataacat tacacttgga aaacctattc caaaaggaga
    71041 tactgtattt atcagatttt taaaatctac tatgtaaact aaattgtcaa aactaaatct
    71101 aggaatttct atttctttac taaatatacc tactattaaa ctcactaaaa tagctgatac
    71161 tacaccatat tctcctaaat gaaataaaaa cttattctta acttttagag tatcaaatct
    71221 ttcagaaaac attacaaaac aagcaaccaa aattcctact gttatagata taggataaga
    71281 atcaaatctc cctttaggat taaactctga tattatagtc gatataccga cacccattag
    71341 tattccacct ttaatagaat ttggtatctt actaactaac tttccagcta caccagttat
    71401 acccattaaa ataaatatta ttcctaaatc tatttgtaaa gctgttaatg cttgtattct
    71461 ttcaatgccc atgctgaact ttaacaaata tgcagttgta agagttatag aagctgtaat
    71521 ccagccaggt acaactgggt ctcccataaa aacatgcaaa cagtataata ttgagttaat
    71581 gatagccata ctccatgcca cttcataggg taatcccaaa atttgtgtac taaggccaat
    71641 tgtgcctaaa cttgtcatac ttgatattat accttgaata gcttctggtt tctcaaatct
    71701 gtaatgtata aatggaattc ttatcttaaa cattccaaat tttatatgag gttgttccct
    71761 tctagcgagt ctttccataa cttcactcca cctttcaata actcttataa gtttacaact
    71821 ttataattgt ttataaatta tcaatgtcat taaaattagt atataacatg caaattatat
    71881 aaacaataaa ttaaatctat aaaattgata gattttgtgc atatatagaa agaccgcttc
    71941 atttttagtt acttaaatca cttaatatta gttatttaaa tcacttgata aaggtttttt
    72001 ataaaattca atagttctat tccatgattc aaactgtcct tttgaatttc cttctacagt
    72061 tccacctgaa gaaaaaatcc ctccactcat actcatacat aaagtctcct ttagaggcat
    72121 aatatatgga attggtaacg gatgacccat attattgtat gttaataatt ctacgttata
    72181 tggataatta ttttcttcaa agatttctaa tgcctttaaa caagcttcat aactattcca
    72241 tatgttatct tcttttccag caatcataag tatatctgct ttggaatttt ctatttttat
    72301 tctagcctct tttctattct ctgctctttt aagacttttc ttataagtac tattaaatcc
    72361 aaatggaata ccttttgata tatttttttt ctgttcttca aagaatatat cattgtctac
    72421 tttgatatat ggaaatggct ctcctttata tgaccatgat gaagtatcat ttccactcat
    72481 caatccatta agagcttgga aacaataaat gtgaggttgt gatactacaa cctttttaat
    72541 ttgttcatat cttgaagcaa gtaaaaaggc caattctcca ccctttgatg tcccatgtac
    72601 aaatatttct ttagtactgg taatttcatt ttcactaatc cactcaaata ctttttcaaa
    72661 atattctaat ggaacctctt ctaatttatc tggtaaccct tctaaagcaa agtatgcaac
    72721 tgttagtaca ttgaatcctc tagatgcaag tggagctgct aaaaggtcta gagcgtctaa
    72781 atttccatca gaaccaccta gcattaaaat tgttttatta ttagaatttt gtttataaaa
    72841 taattttcct ataaactcat cagatatgta ttttgtggta atatcttctg atttaaatat
    72901 tctctttaat tcaacttctt ttctttcaat agaagtttca aatatcatat tcataattat
    72961 tggtttatca atagatatat tttctgcaaa atttttacct tcagttttag atttttccag
    73021 cgaataaatt aaccccatac aattatcagc cttataagta ccttctatag gttcaactaa
    73081 atctaaatct acttctcctt tttcatttga acaaaacact ccataagatg aaaattcttc
    73141 tcccttgcac catggaaatt ccattttcac acttatttta agtttagtat tttgaattaa
    73201 gtccgaaacc ataatcttaa gtctttcatc cacaaatgat tctacattgt atacatttac
    73261 tttcataatc tatttctcct tataataatt atttatgttt tatataaaac agctttatct
    73321 aatgcaacat aaataaattt ttaaattaag acaccatatt gactatttca ttttatcaac
    73381 atattccata tttgtcaaca tattgtcttt tttagtaatt taaaattatg tagtctatat
    73441 gaaatccagt tgatttttgg ctaattaaag ataggaatgc tattaggttt agaatatata
    73501 tattcaaaat aaaaaaccac tcatttaaag aatggttttt aatataaact atttgttatt
    73561 aataaggata tttttttatt taaatttata taatcgaaca tctaatattt aatgtttaat
    73621 aaaattatgc atttgcaaaa gtatatatgg cattaactct tgctacatat aaattctcat
    73681 cactacatcc aatatatcta gcatattttt caatcttttc ttttgcattt tcaacatcat
    73741 tttcatcgct ctccattaac tcatttatat aaatatccat taatgacgct ttatattctc
    73801 ttatatcata gcctaaaaat tcagtcaatc tctcaatttc cttactaaaa tctccatctt
    73861 cttttaccaa aaattcgtat acatcttccc tatatggatt taaagttatt atttgtttta
    73921 ctactttgca ttcgtcagcc ttcccaataa aaccatcttt ataattatta aataaggcat
    73981 tagatttttt tatagattct tcatcaatat aagaatgtac cgcagttata cgattttcta
    74041 taagggcatc tacaacagca taatgaattt taaaacaatc attgtataaa taattgctca
    74101 ttttctttat tgtcgattct atttctaaga agctcgcgtg gccatttttt ttatttttat
    74161 ttggtataat aaaagtttta ttcaaattat taaaaagtct cttaaaatct aaatattttt
    74221 cacaataaac acttttaaag gtatcgatat ctatagttat aattccaaaa cttactatag
    74281 tctcaattcc tttcttaaaa gactcttcta tatatttttc tcctaaactt aaacctctat
    74341 cagatatttg ctttagattt tgaaaactat ttaaacaatc tctctcaaag tttttagata
    74401 tttccaaagc atataattta aagattttcc ttatcttatt ataattattt tttgtatcat
    74461 caaatctgat aatagctcca tttacatcaa aagtaatcat tgagttttaa cctccccatt
    74521 agtttcatca ataaaataaa tttaatataa actttataat cataatatta aacttattta
    74581 tactataatt attaatttga tgataaaagc tattttcctt ctaaataaaa aatttgtcta
    74641 aagtttctaa aaaatttaga caaatcttag gttattactc tttaaattat ttttaaatta
    74701 ttccaaatac gccaaataat attggtataa atatagctgg taacaaattg gctactttta
    74761 tattcgttaa tttaagtaca tttagaccaa gtcctataat taataaactt ccagctgctg
    74821 tcatttctgt gactacagga tcacttaaaa atccatttaa aaatgatgct cccacacata
    74881 taataccttc atacaaaaat acagatattg cagaaaacat tacacctata cctaaagaag
    74941 cagtaaatat aattgaagct attccatcta taacagattt tacaaataaa gtatcatgac
    75001 ttcctgtaag accactttct aatgaaccaa ctactgccat ggctcctata cagaataata
    75061 aactagatga tataaaaccc tctgctatag aatctttttt atttccttta gaaaatttac
    75121 tttgtaaaaa agcacccaac ttatttaccc atttgtcaat atctattaat tctcctatca
    75181 gagcacctac agctacagat attattgtca ctaatgtgtt ttttccttct agtgctcctg
    75241 atataccaat gtacaataca cataaagcaa ttccattcat tatagtatcg cttactcttt
    75301 gaggtaatcc tccttttatt ataagaccta ctatacatcc acctgcaatt gctagactat
    75361 ttgctattac tccaaacatt ttttctcccc tcgattagct aattgaaatt tatcctatta
    75421 ttaaaaccta aacatctata ctttgtattg gatattttaa atattccaaa aattcttcaa
    75481 aaccttttct agatatattt acagttttag tatttatgtt aggatgaaaa tttaagtaat
    75541 cttctttaat tacatcttta tctatgtaaa gctcaacttt tctttctgta tcatttatta
    75601 atgaaaaagg atttacactt ccaggaagaa gtttaagtac attgtatagt ctttcaggtg
    75661 aagcaaacga taatctagaa cttcctatct tatctttaag tgagtttaaa tcaacttgtt
    75721 tttctccttt aactacaata agataatact tatttccttt ggcatttctt aaaaataaat
    75781 ttttacattg acaccccttt gttattccat ctaaaatgac taattgctct gctgtatata
    75841 cagcttcatg ctctactaca tcatattcaa catttaattt atccaaaata tcatatattt
    75901 tagtttcatt catgctagat tcattttcat cttgttcttt tttattattt aaatcactca
    75961 tacttttctc cttaaacact tcatcataat atcattgtga ggtattattc tactatagct
    76021 attgctctta ctggagctcc atcagcatca ttatacttaa atggtgctgc tataaataga
    76081 aatttttctg gaacagtttc taaatttgta agattttcta tgattatttt tcctttttca
    76141 aataaaatat gatgcacttc aaatactgat gtgtcatatc tatccactga tagcatatct
    76201 attcctatgc cttttatatt agtattagct atatagtttg cagcttcttt tgttaatgta
    76261 ggataaccta catagtactg ctttttatcc caaaattttg accaacctga tttaaatatt
    76321 ataaaatcac tattttttat ttcatcttca tattttttta gatattctaa ttctatattc
    76381 tcatttccct tttcaagttc caatacataa gctttcccaa caaaattttc tatatccaac
    76441 ttatctaggg tctcaccttt agtatacata tgtcttggtg aatccatatg agttccattg
    76501 tgagaaaata cactaattaa tgtttcttga taaccatttt cttcaataat agctactttc
    76561 ttgatatctg gtctattagg ctctgcatat acaggcatgt cattatgtgt cacatgagtt
    76621 aaatcaaaaa ccttcatctt tatatacccc ctatgttttt attttctatt atatacctaa
    76681 attcatttta tttctatcag attttattcc attatatacc atactactat atatttttta
    76741 taaacctcaa gggatttacc gaaaaatctt ggaaagaatt atcagtaaat ataacatctt
    76801 cacccaaaaa acgtttatac cttccttctt ctttctttaa agtaattctc tgtttttgtg
    76861 aatgattatt aaaaaccatt atcttaagag gaggtttttt tctattagtc tgcactcttt
    76921 ttaacatgta ttttatgtgc atatcagctt caggaaatga atatccacaa aatattaaaa
    76981 ggtcagtatc tcttaaagtt ttttctgttt cattccaaac attacttaaa aatatgtttg
    77041 acatattctt aaaatatgtt ggtggcacta taataggttc tgttaactca ccacactcta
    77101 aacattttgt ctctgaacta ttttcaataa gcttcatgac accaccttca tgtggtgtaa
    77161 gagttacact attacaaatg gggcaataaa gccaattcaa tgacccatgt atcttatata
    77221 atttgattaa tggttctttt ggttttctcc aatttaactc ctctttaaaa tttgtaaact
    77281 ccacaccata atcaagcata attggcaaat cattcttatc tcttaatcca gtaactgtat
    77341 tgtctatatg tatatcataa tttgcactaa taaaagtagt atcaagaagc aaatcatttt
    77401 ccaaaagatt ttcaactaaa agtttatgat atttattatc tgttctaggt gtattatgaa
    77461 ttgcttcagc cattagtagt attaaatatt gtcttaaaaa acgtatacta tcacttctgt
    77521 tatttagatt ttctagtcca aaatttctaa atgcttcttt tctttgttct gctaagtcta
    77581 aaagacctaa aacttcttca aaggtaggaa aatttgcatt atctatatta tcttttacta
    77641 tatcaatatt gaacatctgt ttaaagaaaa tatacaattc tctattcatt ttggtattat
    77701 aatttgtggg atttagtttt ttaaaatatt cgctaaaaag ttcattttga ataggtagat
    77761 tctctgctgc tgaagctcct gctcctaaaa atattgctat tttcatatag ttcctcctaa
    77821 tataaatatt actcctattt ttatatccat taaatatcca tatcatttat tttatgatac
    77881 aacaataaag ctgtctttta ctagaaaaaa tcctattaca agacagcctt atattatatt
    77941 aaatctttaa taattcgtaa atagaaagag catatatttg agtagctttt ataatatcct
    78001 ctactattaa gtattcatta gcttggtgtt ctgtttctgg ttttcctgga aaaatagctc
    78061 caaatgcaac acaattatct aaagctcttg cgtatgttgc tcctccagat gaaagtggtg
    78121 ttccatcaag accagtttct tcttcatata cttttctaag tgtcttaaca agaagagtat
    78181 cttctggaac atagattgaa tccaagaaat catattcttc ataatttaaa ttgtatttat
    78241 ctgtcatttt ctttaactct tttacaaaat catccttttt gtatgttact ggaatcctta
    78301 catctattcc tgcaaattct ttttcgttat caatagttac tctacctata tttactgtta
    78361 gtttacctga tacatcatcc ttgcaattag gaattatatt gtttccatta gcatcttcac
    78421 caataacttc tgctaaaaac ttaattatat tagaatctat acctatatta ttaagagcta
    78481 tacaaagtct agccactgca tttataccag tatcacttgc tgctgaatgg acactctttc
    78541 caattataca gattttatta ccttcaacag tatattcaaa atttaattta tcaagttctt
    78601 tttttaattt atcagagtat tttccaatat agattgcttt acctggaact gcatttaaag
    78661 cctttccaac tgacaactct atatcacttt tgctatcaca agtcaaatga acttgtaaaa
    78721 gacctttctc tgcatttgtt attgggaatc tagaatctgg agtaaatcca tagtttggta
    78781 tttcttcatt attttcttta tatttattta tacatctcca aagattttct tcatcagccc
    78841 caaaaatgaa tcttatcctc ttattaaagt ctacatttaa atccataaga gctttcactg
    78901 cataaattgc tgctattgta ggtcctttat catcttgtgt tcctcttcca tacaatttac
    78961 catcttctaa aacagcttca aatggagggt aattccagct ttctaaatca ccttctggaa
    79021 ccacatcaac gtgaccaagt atacctatca ttttttcacc ttgtcctatt tctgcatatc
    79081 cataatatcc atctttgtat actgtcttaa atcctaaaga tttacataag tctaagatac
    79141 ctcttaaagc tttatctaca ttttcaccaa atggacaatt ttcagttgct tcagatataa
    79201 cactaggtat ttttacactt tcttgtattg aagaaatcat ttcatcttgt agagaattta
    79261 ctttttcttt aatttgctct ttcatattat cacccttcaa ttttcatcat aatatactaa
    79321 taaatatttt gacctttaaa aaaaaaaata tgcttatttt ttcagttttt ttataaattc
    79381 aatcgctttt aaagtcccca tttttgaatg gtcaaatgta agtccacctt gaaaataaac
    79441 attataagga ggtcttattg gagcatctgc acttaattct atagaagaac cttgtataaa
    79501 tgctcctgct gccattatga cttcactttc gtatccaggc atgtcccaag gaacaggttt
    79561 tacataagaa tcgactggtg cagcttcttg tataccttca caaaaactta ttacttcatc
    79621 agcattatta agtctaatac attgaataat atcacttctt aagtcatcat attttggtaa
    79681 tacatcatat cctaattttt caaaagctct tgagcaaaag atagctccca ttacagcctg
    79741 agatactata taaggcgcca agaaaaaacc ctgaagtaca tttctagttg ttccaaaagt
    79801 aagaccacat tcttttccta ttccaggaga agtcattcta taagatataa gctcaatcaa
    79861 atcttttcta ccagctatat atccacctgt caatgcaagc ccaccaccag gattttttat
    79921 taaagagcca gccataacat ctgctccaac atcagtaggc tctttggtat ctaaaaactc
    79981 accataacaa ttatcaacca ttactatagc ttctggttta acagacttta ttacttctat
    80041 agcttctttt atatcactaa ttgaaagtga ttttctccaa gaatatcctt ttgacctttg
    80101 tatcataacg agtttagttc tatcatttat tttgttttta attccttcta aatctaagtt
    80161 tccatcctct aaaaaatcta catcatcata tgtaacacca tactctttca atgaaccttt
    80221 ttcttctctt atgcctataa ctccctctaa agtatcatat ggtctaccag taacagataa
    80281 aatttcatct cctggtctaa ctataccttg tatacataaa gtaagtgcat gtgtaccatt
    80341 tacaattatt ggtcttacaa gagcatcttc tgtattaaat actttagaat aaatttcctc
    80401 tattttttca cgaccaatat cattatatcc atatcctgta gtccagttaa agtgcatatc
    80461 acttagttta gattcttgca tagcttttaa aactttatat tgattatatt ctcttatttc
    80521 ttttatttct tcaaacttat cttttatttc ttccattatt tcttgcgata gtttaaaagt
    80581 atcatcatct attccatagt agtcttttaa taattctttt gtctcattaa gcattttatc
    80641 acctgtctct ttattatttt atttaaacat gtaaaggaga ctattttact aaaacaaata
    80701 aattatagtt tataagttag tataagtctc ctctcaatca tcttaaatta aattaattat
    80761 ctatctgttg ttattattat tgttgttttg gttttgattt gttagattaa tatactttcc
    80821 aggttgtata gttgatacag catgtttata aatcatgttt tgttgtctat tatccccttc
    80881 tattaatatt atataactat caaacccctt tacaagccct ttaacttgca ctccattaac
    80941 taaatatata gtaacaggta tcctttcttt ccttgcatta tttaaaaaca aatcttgtaa
    81001 atttaaaact gtatttttca ttagatttgt accctcccaa gattaaattg aacttctaaa
    81061 atattcctac cttatattct atataagtta tgacaaattt tcaatattaa gttgtatact
    81121 taaaaattta tatattattt tatagaatct ttaatatata agattatttc attttttaat
    81181 tcgtctatat tttcatattg gtctaaatca aaccattttg ctgttttata tcttttaaac
    81241 catgttatct gacgttttgc ataccttcta gaatctcttt taattatttc aatagcttct
    81301 tcgtatgtat attctccatc cagatacttt aatatctctt tataacctat accttgcatt
    81361 gatatcatat cttttttaaa tcccatactt aaaagttttt ttacctcttc aaccaatcca
    81421 tttttaagca taatatcaac tctcatattt attctttgat acaaatgttc tctatctcta
    81481 tttagaacta ttattattgg ttgatattct tcattaaatt ttaaatcact tgaaaaatca
    81541 ttcattttct taccacttag acaaacttca agagctctta tgaccctttt agtattgttt
    81601 ttatggattc tattagcaga ttcttcatca agttctttta acttattatg catgtaatct
    81661 attccctttt cagcaagctg tttttgaagt tcttctctta attcattatt ggcatcagat
    81721 tgtgcaaaat ccatattata tattaaagag tttaaataaa gtcctgtgcc tccagttact
    81781 aaaacacatt tttccttttc atttatttca tgtatatatt tttttgctct ttgttgaaac
    81841 tctgaaactg aaaatggata gtcaggctta acttcatcta taaggtaatg cttcactcct
    81901 tgcatctctt cctctgtaac ttttgcactt ccaatatcca tatattcata tatttgcata
    81961 gaatcagctg aaattatctc tgcattcata tcttttgcta attttattga caaatctgtt
    82021 tttccaacag cagttggacc tgtaagtatt ataagtggta tttttttcat aacattcctt
    82081 tccatatatt ttaaatatcc aaatatttta cataattctt ttaaacattt tttctatttc
    82141 tgtcttagat atttcgacca ttataggtct tccatgagga catgtaaatg gattctcaca
    82201 cttttctagc tgttccaata aactttttat ttcaatatcg tatattttat catttgcttt
    82261 tatagcagac ctacatgcca tagatgcaaa tctctctcct tttaaatcat aattacttgt
    82321 aatttcttct atattatcaa ttatttgaag tataaatttc tcagtttcag gtactccaaa
    82381 tatagtagga acacatctta ccattatatg attattgcca aaaatttcta gctcaaaacc
    82441 aaatttcata aataactcca agttattttc aatttgaagc atatctacat ttgatacttc
    82501 aataaccact gggtctaaaa gtatttgcat atttatatct tgtctataga acttctccat
    82561 atatctttca tatagtattc tttcatgtgc agcatgttgg tccaacaaat acatagaatc
    82621 gtctttgctc aaaattatat aagtattaaa tacaactcca attacagaat atccgtataa
    82681 agaaaacttg cgttttgaac tacacgagta ttcttcttca ctgtccttaa tactatctcc
    82741 taagtaataa tttccttcat ttttaattcc atcaacttga aactcttctt gtatattatc
    82801 atttgcacta tcttcactta gataattaat gttttttaca tcatcttcta cacttgcatt
    82861 taggacttca cttactgatt gaaattcatt tattggtttt tcacttgata aagtaacaac
    82921 ttcaatgact tcatccttac ctttagtaat attactcttt ttaggagtag attctaataa
    82981 atcattattt cttaatttat aatctgtact tttttctcta ctgttaatag cgattctagg
    83041 ttgtgttttt ttatcactat aagtagcata ctttccaata agatttgagt gtattaattt
    83101 aacctttaaa aaatctctaa gttctatata cacttcttgt tctttttcaa atttaatttc
    83161 aagtttattg gggtgtatat ttacatctat acatgatggg tctacttcta tatttaagaa
    83221 gcacactgca tgtttaccta ttggaattat agacttataa ctttctgtta ttgcatctat
    83281 gattatttta ctttttacaa atcttttatt tatatagata tgttgtaagt ttttatttga
    83341 acggtatata ttgttattac ctatatatcc attcatttta aagtgattgc acttaaactc
    83401 tacatctatt atattttccg ttatttcttt tccatatata cttctaatag tgtttacaag
    83461 ttttccatcc cctggagtat ttagcatctg tttattgtta tttgtatatt taaattgaat
    83521 gtttggatta cctattgcaa gtttatttat caaatcactt atgtttatag tttctgcatg
    83581 agtagatttt aaaaatttct gtcttgctgg tgtattaaag aaaatatctt ttataatgat
    83641 ggtagttcca ttagtagaac ctattggttc tttcgatatt atttttccac cttcaacata
    83701 tattttagtt cctattattt catctttagt tttagtcgtc atttctaatt ttgatacagc
    83761 tgaaatagat gccaatgctt ctcctctaaa accaagagag tataaatcat acaaatcatc
    83821 aattttttta attttactag tagcatgtct caaaaatgat ttttcaactt cacttgaagg
    83881 tattcctatt ccattatctg taatcttaat tagacttttt cctccatcaa ttatatctat
    83941 ggaaatttta tttgcacctg catcaatgga gttttcaata agttctttta ctacagaaga
    84001 aggtctttct acaacttcac ctgctgctat cttatttata gtcaaatcat ctaggatgtt
    84061 aattatattt ttcattttta cacctctaag attttatttc ttttgctttt ctttgaagat
    84121 tataaagaga gtttatagca tctaatggag tcatatttaa aatatccaga tttaaaattt
    84181 cttctgatag tatatctcta tttacactat caaaagagat ttgagttaag gctacttctt
    84241 ttacagaatc ctcttgatta attttctctt tatcatcatt ttgcttcatt aaagcaactt
    84301 catcatttaa tgctttaaat ttagaattta atttatcata atcctttttt atatgtttgt
    84361 aatcttttac tataagttca tgttctattt ttagagattc atatttattc ttaaaattac
    84421 tttgatttac cttaactaat tcttcgtcca aattactatt aattatatta ttgttttctt
    84481 tatctccatt tattgcaaca ctgttgtaaa catgattttt ttccaagtct ttaagtatat
    84541 attttgctct ttctatgact tcgtctggta atttagctaa tttagcaaca tatattccat
    84601 aactcttgtc tgctccctga ggaattattt ttcttaaaaa tattattcct tccccatctt
    84661 ctttgactgc tattgaataa tttttaacct ctttaaactc ttcttctaaa tcagtaagtt
    84721 catgataatg tgttgcaaat aatgtcttac atctaatatt tttttgaata tattccacta
    84781 ttgaccatgc taaacttata ccatcatagg tactagttcc acgacctatt tcatctaata
    84841 taactaaact tctctctgtt gcatttttta atataaggga tacttcgttc atctctacca
    84901 taaaagtaga ttgaccttga gataaatcgt cactagctcc aactcttgta aatattctat
    84961 ctaatattgg aatatcagca gactctgctg gtacaaatga gcctatatgt gccataagag
    85021 ctattatagc agtttgcctc atatatgttg atttacctga catattagga ccagttatta
    85081 tgttaataat gttttctcca cgatttaaat aagtatcatt tggaacgaaa ttttcctctc
    85141 ctactatatt ttcgacaaca ggatgtctac catttcttat atcaagttta ttattttcat
    85201 ttattgctgg ttttacgtag ttatttatat gtgcaactgt tgcaagggac acaaaaacat
    85261 ctatattagc tatagtctta gccacttttt gtattctatc tatgttttta tatattgtat
    85321 ctcttatctc tacaaatatc tcgtattcta aagatttaat cttttcctct gcatgtagta
    85381 tcttttcttc tatttccttt aattctggag ttatatatct ttctgcatta ctaagtgttt
    85441 gctttcttat atatgtctca tctagctttg cctgtttaaa gttagctttt gttatttcta
    85501 tataatatcc aaaaacttta ttaaagccta tttttaatga tttaactcct gttttttctc
    85561 tttccctgtt ttctatttcc tttacaagaa aggctccatt cttagaaatc tctcttagtt
    85621 ccttaagttc atcactaaaa tctgatttaa ttatgtttcc atcttttatg gttatcgtag
    85681 gttcttctag aatagcttca tctattaaat tgtatatatc atctaattta tccatttctg
    85741 aaacatactc ttttaggatt tttgcatttg ataaatttat agtatctttt aaattaggta
    85801 acttttctat cgaatttttt aagtgaatta actcttttgg tgttactctc tcaaatgcta
    85861 tctttccaca tattctttct atatcgtata tatttttaag tatatcattt aggtcttctc
    85921 ttaatataaa gtcatctttt atttcttcta ttacatctaa tctattttca attttagatt
    85981 tatttatcaa aggttcttct acatattttc ttaaaagtct acctcccatt gctgtagaag
    86041 ttttatcaag tacgtgtaat aatgaacctt ttttcttatt ccctcttata gtttgagtaa
    86101 gttctaaatt agttctagta aacatatcta aaaccatata ttctgatgaa ttgtatatat
    86161 ttatattatt aatgttagat gttatttgtt tttgagtatt gtatatataa ttcagaagaa
    86221 ttgataagct tgactttatt agacctttat catcaaactt tagtttttgt agataaacat
    86281 ctggaaaata ttcttttaat atatttatat ccaaatagtt atcactaaaa ctttcattta
    86341 tgtatatatt acttacagta gctatatctc taagcttttc tataaagtct aaatcattta
    86401 taattatttc agttggatgg atttttgcaa tttcttcaat taccttatct tcatttaaac
    86461 atgttgcatt agtttctcct gtacttatat caacataagt tagacctata ttagtaccat
    86521 ccttatacaa agataataaa taattattct ttttattttc aagtaaattt ccatctaaaa
    86581 ctgtaccagg agtgatgacc cttataacct ctcttctaac aattcctttt gctgtagatg
    86641 ggtcttccat ttgttcacct attgctactt tatatccatt ttcaactaat tttgatatat
    86701 atgaattggc tgagtggaaa ggaacaccac acataggagc acgttcttct aaaccacaag
    86761 cttttcctgt caatgctatt tcaagagctt ttgaagctac taatgcatct tcaaaaaaca
    86821 tttcataaaa atctccaagt ctaaaaaaca gtatacagtc tttatatcta ttttttactt
    86881 caagatactg tttcatcata ggagttaatt tattcatatc tatttgcatt atcaaacctc
    86941 cttcttttct aattaaatat tatatcatag tagatgatta ttattaacac aatatataaa
    87001 attttgacat ataactaaaa acaatccaaa atgtatactc acattttgga ttgctaagtt
    87061 taatgcttat taaataaaaa tatttttttt tacaataaag atattatttc ttttttaagt
    87121 ttaatgatat tttcaaggtt atcttcattt aactttctac tatctataac aaattctttc
    87181 tttactattg atggtttttt tgaaataaca taaattctgt ttgatagcat tatagcttcg
    87241 tcaatatcat gagttataag aagtattgtt gaatttactt ttttcttaac atctaaaagc
    87301 catttttgca tggatgtttt agttaatgaa tcaagtgccc caaaaggctc atctaaaagc
    87361 attatgtcat tagaatttat aaaagttctc aagaagttag ccctctgtct cattcctcca
    87421 gaaagttctg aaggatattt atcttcatat ccgcttaatc caaacacctc aaaataaggt
    87481 tttaccattg acctagcttt actctttttt tcttttttta aaattagtgg tagtgacaca
    87541 ttatctatta tagttttata tggcaagagt aaatcttttt gatacatata actatactta
    87601 ccatttatat tcactttgcc actatcataa tctgtaagtt tagttataat attaaaaata
    87661 gtactttttc cacatccact tggccctaat atagaaacaa actcaccttc ataaacatca
    87721 atacttatat cttttaaaac tttaatatct ttataagttt ttgatacatt ttctatagat
    87781 acttttactt ttttattgtg gtaaaaattc atttgtgtaa gcatcacttg ccttcatatc
    87841 cttatctatt aatttatatt cttttaagaa tgatgtatag ttgttccata cactatcttt
    87901 catttctccc catcgtggtg catcatcttt gtacttgctt gctaaatatt cttgactctt
    87961 taaagctagt ttttcatcta cttcaggtgc atgttttact aaaatttttg ctgattcttc
    88021 tggatttttt attgcatatt cataaccttt tgttgtagct tttaagaatt ttttagcaag
    88081 ctctggatta tctttaagta cagtttcatt agaaattata agtggtgtat aataatccaa
    88141 tctctcatct aaatctttta ctggtataaa gtttaagtca tatccaatta aatcagcttt
    88201 aactgcatcc caaccttcaa atatccatgc aaaatctaca gttttcatag ctgcaaagaa
    88261 atcatcttga ccagtattaa ctatctttaa cttattaaaa tcagctccat ttttcttcat
    88321 aactgcttta aaaacagctt cttctgatgg agagccccaa ccaccataag tttttccttc
    88381 aaaatcttta gctgttgtta tattcttttc ttttggtgat gcaaacccag aagtattatg
    88441 ttgtataaca gttgctacag cttttattgg aagtggatct tcactagtct ttgcataagt
    88501 aacttgttct tgatagctta taccaaagtc agcttttcct gttgctacta aagtttctgc
    88561 tccactttca ggtggttgta ctatttcaac atccaaacct tcttctttat agtaaccctt
    88621 atcaagtgct acaaataatc cagtatgatt tgtatttggt gtccaatcaa gcaccatagt
    88681 tactttttta gaagaagtat ctttatcatt gtttttgtct ttattgttat ttgaagaaca
    88741 tccagttatt gttgccaatg taaaaacact tactaaacct aatattccta actttttaaa
    88801 attcataatt gcctccctca aataccttta atctattaat ctatgtctta taacaacttt
    88861 ttttacagcc tgtacaattc ctacaaacat taaactaaat ataactacta atatagtaga
    88921 tgcaaatact ttatcaagtg catatgcact ttttgaccta agcatataaa caccaagtcc
    88981 tttcgttcca cctagccatt ctgcaacagt tgctgccatt acagcatacg ttgcagatat
    89041 tttaagtcca gaaaaaaatt tatccattgc cataggaaat ttaaggtgaa tgaatgtatt
    89101 aactttattt gagtccatag tcttaaataa atttaaataa tctttatcaa tattctcaat
    89161 gccatctaca aaacttatta atataggaaa aaaacaagta agcattacca tcaatacttt
    89221 tggcattgtt ccaaatccaa accatatcat aaagagtggt gctataatta ttgtaggtat
    89281 catctgtgta accaacataa taggataaag acattttttt attattgata caaaatccat
    89341 caatattcca attaccaatg atattataat tgcgactata aaaccaagta ttgcttctcc
    89401 tatagtaacc acagcatgca tggataaatt ttgataatct ttaaaaaaca cattaattat
    89461 atctactggt gtgggtagta tatactgagg aacttctaaa actcctacca tagattgcca
    89521 aagaataagt ataaacaaaa atgttgctat tggatatata ctatctttga ctttatctat
    89581 gatttctaag tttttcatct atagtcagac ctccagcttt ttcatctact ctagctactg
    89641 ttatgactct ttcacatcca agattaaaag ggattttatg tacctttttt aataattcaa
    89701 aaacttcatc aaaatcacct tcaacagtag tgctcattgc tcctatttca catttaagac
    89761 cacttttttc aatttcagca atacaagcat ctactacttt atacatctct tcttcacctt
    89821 tgtaaggtct tagtggcatt actgctatgt ctgcgattac catttaaatc actcctttaa
    89881 aaataattaa tacctactag gtatattttg ttttttatta aaaaatttta ttactaaaaa
    89941 gatattatat ttaaataaaa gaaaagtctt atccaaaata ggataagact tatttttatc
    90001 ttaactggtc tccctacact ggcattatcc aaacaggttc aaagggtcga gataaaatct
    90061 cctctcagca cattagctcc ccgaaatata ttatatcttt tctacttgat tatactacac
    90121 ttatcatatt ttaacaaatt ttttatttat attagatatt ttatccgttc aaaaatatct
    90181 aatataaatt gtacattatt acaccaaata aattatctta aaatgctaat ttatcaacat
    90241 cttccaaaac tagattaact gaattttcta gtttttattt tgctatttca agcatatttg
    90301 gatgtatatc aattccatac aaatattgtg ctaaatttct gttttcactc atctaatttg
    90361 caatcgttac agattacaga ttagaaatag cttttagact ctacttatct ttatctacaa
    90421 aaaatccttc aataaattca gtaataatat tcagtaatct aaaaataaac ctctatctag
    90481 atttttaaga tacaagcctt ttaataagta ccttttgtga taatataaaa attactcgtc
    90541 attatcatca aaatcctcag caaccaacat tttagataag aatcaaactc tataatataa
    90601 ttattttatc caatttattt ttgagaaata aaatattttt ttaattttta aattttttaa
    90661 tatgcacctt gaaaaaagaa acgttttcct atattatggt aatagtagaa taaaactaaa
    90721 taggcaaaac tagagaaatt tagtgacgca aagctatagg gactaagact tatgaaatga
    90781 gttatgtcag ccagttgcca aagagatatt ttctttttgt ttttatgaat gttttttagg
    90841 gggatatatg atatatgttt atggataaaa tggatagatg tacacatata ctaactgcat
    90901 atatatgcag ttcacgcgat tactgcaatt ttatagatac acaattaaat gattttatac
    90961 tagaatatgg agagaatgtg gtagaatctt gtttgcatca agtgatggta ttggtaagca
    91021 gatataatta aagaaatttt attttctaga aaaccctttt tagttttatc tacgttttat
    91081 aattcattaa agaactaatt aaaataagct tcattatata tttttcatga agtaaacagt
    91141 tgagtttatc tcatatactg tttaccccaa ttacataatt ctaataatat agattccaat
    91201 gatttaccac gtttagtaga caaatattca acttttggag gaatagttgg ataagaaatc
    91261 ctcttaataa gtcaatctct ttcaaaatac tttaattctt gtgacagtat cttatgactt
    91321 atatgaacaa cttctttttt taattgactg taacgtattg gctcttgttt taaaatatgc
    91381 cataaaataa ttgccctcca tttacttcct atcacagtca tggtaaaacc aattgaacaa
    91441 ttaaaatctt tttgtctttc ttcaatattt ggaaattctt caaaattatt atctatatcc
    91501 atctcaatcc tatctttcaa aatagtaagt atctaactaa aaagtgcatt cttgtttagc
    91561 gtactaattc gtaatataat cttgattgta gtatagagcc ttacataata ctactttttt
    91621 agatgtatat gtttaaattt taatatagac ataggttatt ttattaattt tatttaaaca
    91681 gataataata aataataatt tatctcaagt tttctatgta gataaactaa tctaatgttt
    91741 agaaaggatt atataatatg aataaaaaat ttcgtcttta tcaagttgac tcatttacaa
    91801 aggaaaaatt tacaggtaat ccagctggtg taattacaaa tgctgatggc ttatctgaat
    91861 cacaaatgca aaaaatagca agagaattaa ataattcaga aactgctttt attttcaata
    91921 acttggctaa aaatcatcaa gaaaattatg atgtacatat cagatttttt acaccaacta
    91981 atgaggttcc tatatgtggt catgctacta ttgctgccca ttatgttaga gcagtagaaa
    92041 accaattcaa taacaaaaca gtatttcaaa aaactggtgc tggaatatta ccagttgata
    92101 ttataaaaaa agataatgat tatgaaataa ttatgacaca aggaaaaatt gaagtacctc
    92161 caccattaca acaaacctat caaaaaagat tacttaatgc atttggtatt ttaaagaaag
    92221 atattcgtac agattgtcct attgccatat catctacagg acattcaaaa gttatgattg
    92281 gaataaagga attatcaaca ttaaatagtt tatctccaaa tttatatgaa ttatcgaaaa
    92341 taagtcaaga aataaaatgt aatggacatt atatttttac attacataat aaagaaactc
    92401 tacaagttca tggaagaatg tttgctcctg caattggtat ttcagaagac cctgttacag
    92461 gaaatgctaa tggaccctta ggtgcgtacc ttgtacatta taaagtaata cctacaccca
    92521 acacagagtt tatatttgaa gcagttcaag gagaagcaat aaaacgcaaa ggcaagatgt
    92581 tagtaaaagt aattatttta gataataagc cagttgaagt aaaaataatt ggaaaagctg
    92641 taattgcatt ctcaacaaac atagaaatct aattatagat tccttctaag taaatttttg
    92701 aactttttaa tactaattta ataacaaact aatttatata caatcaaatt aattttttta
    92761 ttatttgtta atatatattt atcattatat tatataataa tatagatagt tactatatct
    92821 tataattaga taaatcataa ttatatatta ttgttaaaac tcaattatat aatttttaat
    92881 aatattattt taggaggtaa aaatgataaa cgatattaaa aataaattca aaaattacaa
    92941 accatatata aatggataca agaatatgaa gagagcatct gttttaattc caatagtaga
    93001 aataaataac acacactata tattatttga agttcgctca aaaaatttga agcatcaacc
    93061 tagcgaaatt tcttttccag gtggtaaaat agaatcaggt gagactccat atgaagctgt
    93121 tattagagaa acttgtgagg aacttggaac ttttagtgac aatatagaag taatatcaag
    93181 tcttgacctc cttataacac cagtaaagtt tatcatacat ccatacttag gatatataaa
    93241 aaatattaat aatttaaata taaacaagga tgaagttgac catacttttt tggttcctat
    93301 aaaatatctt ttagagaatc ctccaaatac ttatagtaat actgtaaaag tttttccaga
    93361 tgaaaatcta ccatatggtt caattccaaa ccaaaaagat tataaatttg aaagtggaag
    93421 ttatcctatt ctgttttata aatataaaga ttatgtaatt tggggaatga cagcaaaaat
    93481 actagaaaac tttttaaatt ttttatcaga ataacactca taataaatca tcaaaacttt
    93541 tacataagaa atttataaaa gtttctaaat ttaacaattc taaaatatca ataactatat
    93601 tttgtagcac ttttttattt tattattgtt tgaatatttg atggttttca atgcaatttc
    93661 aacataaata ctatgtatta gtgtatactg ttgatgaatt aaagtatgat aatctattta
    93721 ataaagtatg aagtaaatga ttttaatgtg tctttatggt aaaattacta ataagtaata
    93781 aaattaatta aaatatatgg aggtgcttat aatgtttgct gtaggatttg ttgttataat
    93841 tgcacttgcc tttttcattt taagtgtact attatttaat ggaaaagcca gtatgctact
    93901 agcaggttat aactctatga gtaataaaga aaaagcacga tacgataaaa aaaaattatg
    93961 tagaagttct agcattgtta cttttattgt ctctataatg ctatttatta tggcgttttt
    94021 gggatataga atagagagtg gtcaaatgga cgaaaaaaaa atggttccct tttctataat
    94081 atttataata gtcatacttt ccagtgtatt ttttaatatc ctctactcta acaaaaaatg
    94141 taaaaaataa atagttgtaa gttgagcagt taattataaa agattgactg ctttttcatg
    94201 tatattgact actcttatta aatattttaa catttaaaaa tctatgtaaa aataatgaat
    94261 atagtacaaa cttctaataa tgattttacc tttgtggtta cagtccacta tatataattt
    94321 aatatgataa cagggaatta ctaatgacaa ctaagtaaac ttttataaaa tataataaaa
    94381 caaaaataga tgtacaatga aattatatct tatatcaaat ttatttttat taatagcaaa
    94441 aacttacatt agtataacat atgacaaatt cgcttaaaat aaaaattttt aatataattt
    94501 gttctatagt acatctattt tgattagttt gcataatttt attattttgt acaatattaa
    94561 ttatttacta atatcccatt taatgaaaaa gttctaggtt cagtaatttt gaccataact
    94621 aatttaccaa ttaaatcatc atttccacct tcgaaattta cgagtttatt ttgtctagtt
    94681 ctaccagcaa acttattttc attattttta cttcttcctt caactagaac ttcaactatt
    94741 ctatctttat atccatcatt tatttctgca gaaatcctat ttacagcttc taacacccta
    94801 ttaaatctat catgctttat atcttctggt atttgatttt ccattttagc agcaggagtt
    94861 ccctgtcttt tagaataaat aaatgtaaaa gctgaatcat atctaacttt ttcaaccaca
    94921 tctaaagtgt ccaataaatc ttcttctgtt tctcctggga aaccaatcat taagtctgta
    94981 gaaaaagcaa tacctggaac ttccttttta gctttttcta ttatttctaa ataatattcc
    95041 tttgtataat gtctattcat ttttttcaaa aggctactgc ttccacattg tattggtaga
    95101 tgtaaaaact cacacacctt atcacaatct ctaattgcgt atattacttc atcagatata
    95161 tcttttggat gagatgtcat aaatcgaacc ctttcaattc cttctatatc attcactttt
    95221 cttaaaagtt ctgagaatga aactggattt tcaagtgtct taccataaga atctacattt
    95281 tgtccaagta aagtgatttc tttcgttcca tttgcaacaa gctcttttat ctcgttaatt
    95341 atatcttcag gagttctact tctttctctt cctcttgtgt atgggactat acaatatgtg
    95401 cagaaattat tgcatccata cattatattt acaaatgctt ttaattcaaa ttttctatta
    95461 cttctaagac cttctattac ttctccatca acatcccata catccactaa cattttgtca
    95521 gaatttattg attctgtaag taattgcgga aatttatata gattatgtgt tccaaatata
    95581 aggtctacat gtttatattt ttttcttaat tcctctacaa catgtggttg ttgcatcata
    95641 catccacata cagctatttt catatctgga ttttttcctt ttagatgttt taattgtcct
    95701 aagttaccat atacttttag ctctgcattt tctctaactg cacaggtgtt atatattatt
    95761 aaatcacttt cttcaaccat cattgacatt tggtatccca tctcttctaa cattgaacat
    95821 aatttttctg aatcatgttc attcatttga cacccgaagg tttgagtaaa cacgagtttt
    95881 ctctttccag ttctgttgaa gtattcttca ttttgtctgt gtatttgttc tatatattta
    95941 tcttgttctt gtattttctc tataggtatt gttacttgtt ttcttttgct cacgtctatt
    96001 cctcctagtt aatttcttat attacacata accttaatta tatcaaataa gaaaaatctt
    96061 ttaaagatat tattattttt ctagttgtgt tttaatagta aatctaatga tttatatata
    96121 ctatatttct aaaatataaa atcatataat tattataata ataaaaagat gttttaaatt
    96181 aaaacttaaa acacctttcc ttaaataaaa tatatgattt actattaaat acaattacat
    96241 ctattcattt tcaattaaat aacaatcatt taatattaaa tattgacctt cctcaaccgt
    96301 tatatatctt cttcctgaaa aagtatcatt agtaactatt ccctctgcat tacctaagct
    96361 atcatttcta acttcataat atgcatcaga agaatttgac attataatat attctccagc
    96421 aggaatttct aatccaattt tatacatacc atttccaaac ttaccattct tggccttctg
    96481 ggctttagca tactttgcta atgtcattgt tgaatcctca attttaatat attgaccatt
    96541 ctttaaggtg atatatctag tcccactaaa aatatcattt gaaagtatac tatcagcatt
    96601 acctgtacta tcacttgtaa cttcataata agaagcataa cttcctgagt ttgaagttat
    96661 taagtattca cctgctgaga tatcttttcc aaccttatac attccatctt ttatagtctt
    96721 tgtagtaggt ttaacatttt ttacaacccc agtattaata tctccaattc catttgttat
    96781 atttaaacac tgttgtacta tatttgaatc tatatatcct atagaagtta tcttcttagc
    96841 attttttaaa atgcttttat tgctaccatc attaactaaa accattggac catgttttga
    96901 taaagaagat cctacaagtg catttgttaa ttcataagct ccagctatat aaaactctct
    96961 agcatcctta taaaacttat ttattattgc tttattagtt tcaaaacgag tactcccccc
    97021 tagtctagta gatttagtat tgtttactaa agtggtactc attgaagctg ttcctcctat
    97081 tacataagac tttaaaccac tagttgaaaa aggtatactt tgtccattag taagaattat
    97141 tggtgcttta tctcttgctg ctacagatgc aatacttata gcatctgctt ctcctttata
    97201 tgcattggtt agcataacag tattgacttt ttttattgaa tttatttctt ttgcaacatt
    97261 ataacttgtt tttattctgt catttccctt aattcttaca actttcattt tcttagattt
    97321 taatgaattt tcgacagatg tactaataga atatgttcct ccaattatat aaacttttga
    97381 tacatttttt aatcttgcag atgtctcagt tggtatagta tttttttcag ttaatagtat
    97441 aggggcattt aaagctcctg ctagtccact tgcacttaat ccatctgcaa tagagttact
    97501 agtattaatt aatatagcag ttttatatgc atttttatct gctattttac ctgcgatttc
    97561 atacttattt tttccttgta ttttttctac agatgatatt gcatctacta attgaatatt
    97621 tgcaaataca aaagaaatac ttaaagtcaa tgttaatatt cttttataga atttcataat
    97681 aaaattgtcc ccctcataat aaatttttaa tatataaata catattctta aattagttat
    97741 gtacttaaca aacttatgta aaattgcaaa ttatattaag catattacaa ataaatatta
    97801 atacaattat tcatttagct ataattgtat ttacatttat attaaaaatc aactagattt
    97861 gtataaatac ttataattat atttttattc ttaatatttt ttttattatg ttattttaat
    97921 agatttattt ttctttttta agcatagaga tgtatttttc catatattct atttctatta
    97981 tagtttcgct tatttaattc accaaaaatt tcacttaata ttagaatttt aaatct
//
LOCUS       DAEOTL010000004        94786 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEOTL010000004 DAEOTL010000000
VERSION     DAEOTL010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 94786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94786
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.004"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            177..1067
                     /locus_tag="KRH82_000464"
     CDS             177..1067
                     /locus_tag="KRH82_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBG8653764.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            1285..2571
                     /locus_tag="KRH82_000465"
     CDS             1285..2571
                     /locus_tag="KRH82_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBG8653765.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTKKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(2660..3103)
                     /locus_tag="KRH82_000466"
     CDS             complement(2660..3103)
                     /locus_tag="KRH82_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBG8653766.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(3127..3921)
                     /locus_tag="KRH82_000467"
     CDS             complement(3127..3921)
                     /locus_tag="KRH82_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBG8653767.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(4487..4963)
                     /locus_tag="KRH82_000468"
     CDS             complement(4487..4963)
                     /locus_tag="KRH82_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBG8653768.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(5064..6233)
                     /locus_tag="KRH82_000469"
     CDS             complement(5064..6233)
                     /locus_tag="KRH82_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8653769.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            6396..7259
                     /locus_tag="KRH82_000470"
     CDS             6396..7259
                     /locus_tag="KRH82_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBG8653770.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            7330..7923
                     /locus_tag="KRH82_000471"
     CDS             7330..7923
                     /locus_tag="KRH82_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBG8653771.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(8174..8809)
                     /locus_tag="KRH82_000472"
     CDS             complement(8174..8809)
                     /locus_tag="KRH82_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBG8653772.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(8889..9620)
                     /locus_tag="KRH82_000473"
     CDS             complement(8889..9620)
                     /locus_tag="KRH82_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBG8653773.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
     gene            9951..12140
                     /locus_tag="KRH82_000474"
     CDS             9951..12140
                     /locus_tag="KRH82_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBG8653774.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
     gene            12551..14479
                     /locus_tag="KRH82_000475"
     CDS             12551..14479
                     /locus_tag="KRH82_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBG8653775.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            14466..14813
                     /locus_tag="KRH82_000476"
     CDS             14466..14813
                     /locus_tag="KRH82_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBG8653776.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(15055..16974)
                     /locus_tag="KRH82_000477"
     CDS             complement(15055..16974)
                     /locus_tag="KRH82_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBG8653777.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(17000..17806)
                     /locus_tag="KRH82_000478"
     CDS             complement(17000..17806)
                     /locus_tag="KRH82_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBG8653778.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            complement(17865..19313)
                     /gene="ddlR"
                     /locus_tag="KRH82_000479"
     CDS             complement(17865..19313)
                     /gene="ddlR"
                     /locus_tag="KRH82_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBG8653779.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIATIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            complement(19337..20236)
                     /locus_tag="KRH82_000480"
     CDS             complement(19337..20236)
                     /locus_tag="KRH82_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBG8653780.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            20494..21750
                     /locus_tag="KRH82_000481"
     CDS             20494..21750
                     /locus_tag="KRH82_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBG8653781.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            21808..22587
                     /locus_tag="KRH82_000482"
     CDS             21808..22587
                     /locus_tag="KRH82_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8653782.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(22691..23275)
                     /locus_tag="KRH82_000483"
     CDS             complement(22691..23275)
                     /locus_tag="KRH82_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBG8653783.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(23475..24905)
                     /locus_tag="KRH82_000484"
     CDS             complement(23475..24905)
                     /locus_tag="KRH82_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8653784.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            25223..26167
                     /locus_tag="KRH82_000485"
     CDS             25223..26167
                     /locus_tag="KRH82_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBG8653785.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKICYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            complement(26438..27373)
                     /locus_tag="KRH82_000486"
     CDS             complement(26438..27373)
                     /locus_tag="KRH82_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBG8653786.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMVETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(27492..28085)
                     /locus_tag="KRH82_000487"
     CDS             complement(27492..28085)
                     /locus_tag="KRH82_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBG8653787.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            28192..28620
                     /locus_tag="KRH82_000488"
     CDS             28192..28620
                     /locus_tag="KRH82_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBG8653788.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            28687..29355
                     /locus_tag="KRH82_000489"
     CDS             28687..29355
                     /locus_tag="KRH82_000489"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBG8653789.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVENIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(29473..30828)
                     /locus_tag="KRH82_000490"
     CDS             complement(29473..30828)
                     /locus_tag="KRH82_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8653790.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFVICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLAFLKKNFSTLDSNLNKV
                     A"
     gene            complement(31737..32081)
                     /locus_tag="KRH82_000491"
     CDS             complement(31737..32081)
                     /locus_tag="KRH82_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653791.1"
                     /translation="MNNNKFVAPNNVTLVERCYRYIKDRECSFSPNTIRNRKNMIKNQ
                     IEVFFKDMKLIDITPSILQSYINNIYNEHMLNSTKNQVDFIKLVLKESYRLKEISENI
                     CDFVTTPIKKIV"
     gene            32114..32260
                     /locus_tag="KRH82_000492"
     CDS             32114..32260
                     /locus_tag="KRH82_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653792.1"
                     /translation="MVFETFDKAIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            complement(33013..33258)
                     /locus_tag="KRH82_000493"
     CDS             complement(33013..33258)
                     /locus_tag="KRH82_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653793.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIISFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIIFANCIMFSNILLEIFLIYICRKFRKI"
     gene            33883..33987
                     /locus_tag="KRH82_000494"
     CDS             33883..33987
                     /locus_tag="KRH82_000494"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBG8653794.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     repeat_region   34517..35336
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=34517..34545
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(35727..37460)
                     /locus_tag="KRH82_000495"
     CDS             complement(35727..37460)
                     /locus_tag="KRH82_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8653795.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     gene            complement(37700..38545)
                     /locus_tag="KRH82_000496"
     CDS             complement(37700..38545)
                     /locus_tag="KRH82_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8653796.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            complement(38576..40810)
                     /locus_tag="KRH82_000497"
     CDS             complement(38576..40810)
                     /locus_tag="KRH82_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8653797.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQHIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSKKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            41594..42403
                     /locus_tag="KRH82_000498"
     CDS             41594..42403
                     /locus_tag="KRH82_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8653798.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            42548..42787
                     /locus_tag="KRH82_000499"
     CDS             42548..42787
                     /locus_tag="KRH82_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653799.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(42974..43150)
                     /locus_tag="KRH82_000500"
     CDS             complement(42974..43150)
                     /locus_tag="KRH82_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653800.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(43204..43300)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(43655..44329)
                     /locus_tag="KRH82_000501"
     CDS             complement(43655..44329)
                     /locus_tag="KRH82_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBG8653801.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(44549..45103)
                     /locus_tag="KRH82_000502"
     CDS             complement(44549..45103)
                     /locus_tag="KRH82_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBG8653802.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILDK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(45181..45546)
                     /locus_tag="KRH82_000503"
     CDS             complement(45181..45546)
                     /locus_tag="KRH82_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653803.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            46011..46796
                     /locus_tag="KRH82_000504"
     CDS             46011..46796
                     /locus_tag="KRH82_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8653804.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKEHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(46893..47717)
                     /gene="pdaA"
                     /locus_tag="KRH82_000505"
     CDS             complement(46893..47717)
                     /gene="pdaA"
                     /locus_tag="KRH82_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBG8653805.1"
                     /translation="MKKDSLKKYIMIGAFALVLFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            47938..51057
                     /locus_tag="KRH82_000506"
     CDS             47938..51057
                     /locus_tag="KRH82_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBG8653806.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIHTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     NFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKGGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            51075..51674
                     /locus_tag="KRH82_000507"
     CDS             51075..51674
                     /locus_tag="KRH82_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBG8653807.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(51916..54045)
                     /locus_tag="KRH82_000508"
     CDS             complement(51916..54045)
                     /locus_tag="KRH82_000508"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBG8653808.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYDKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            54311..54559
                     /locus_tag="KRH82_000509"
     CDS             54311..54559
                     /locus_tag="KRH82_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653809.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            54725..56116
                     /locus_tag="KRH82_000510"
     CDS             54725..56116
                     /locus_tag="KRH82_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBG8653810.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            56227..57696
                     /locus_tag="KRH82_000511"
     CDS             56227..57696
                     /locus_tag="KRH82_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBG8653811.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVVINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            57761..58354
                     /locus_tag="KRH82_000512"
     CDS             57761..58354
                     /locus_tag="KRH82_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBG8653812.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            58536..59882
                     /locus_tag="KRH82_000513"
     CDS             58536..59882
                     /locus_tag="KRH82_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBG8653813.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            60064..60435
                     /locus_tag="KRH82_000514"
     CDS             60064..60435
                     /locus_tag="KRH82_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBG8653814.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            60428..61117
                     /locus_tag="KRH82_000515"
     CDS             60428..61117
                     /locus_tag="KRH82_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBG8653815.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            61637..62503
                     /locus_tag="KRH82_000516"
     CDS             61637..62503
                     /locus_tag="KRH82_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8653816.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            62745..63554
                     /locus_tag="KRH82_000517"
     CDS             62745..63554
                     /locus_tag="KRH82_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653817.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            63698..64762
                     /locus_tag="KRH82_000518"
     CDS             63698..64762
                     /locus_tag="KRH82_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBG8653818.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSIKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            64790..65509
                     /locus_tag="KRH82_000519"
     CDS             64790..65509
                     /locus_tag="KRH82_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8653819.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            65533..66117
                     /locus_tag="KRH82_000520"
     CDS             65533..66117
                     /locus_tag="KRH82_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBG8653820.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            66119..67468
                     /gene="pabB"
                     /locus_tag="KRH82_000521"
     CDS             66119..67468
                     /gene="pabB"
                     /locus_tag="KRH82_000521"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBG8653821.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTSIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            67458..68201
                     /locus_tag="KRH82_000522"
     CDS             67458..68201
                     /locus_tag="KRH82_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV family protein"
                     /protein_id="HBG8653822.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYTKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDVPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            68235..68936
                     /locus_tag="KRH82_000523"
     CDS             68235..68936
                     /locus_tag="KRH82_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653823.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVEIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRNIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            68962..69534
                     /gene="folE"
                     /locus_tag="KRH82_000524"
     CDS             68962..69534
                     /gene="folE"
                     /locus_tag="KRH82_000524"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBG8653824.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            69598..70389
                     /gene="folP"
                     /locus_tag="KRH82_000525"
     CDS             69598..70389
                     /gene="folP"
                     /locus_tag="KRH82_000525"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBG8653825.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSYGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            70400..70765
                     /gene="folB"
                     /locus_tag="KRH82_000526"
     CDS             70400..70765
                     /gene="folB"
                     /locus_tag="KRH82_000526"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBG8653826.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVRVRVRKPEA
                     PVNGIYDYFGVEIRRARDE"
     gene            70758..71264
                     /gene="folK"
                     /locus_tag="KRH82_000527"
     CDS             70758..71264
                     /gene="folK"
                     /locus_tag="KRH82_000527"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBG8653827.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEKLIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            71245..72030
                     /gene="aroF"
                     /locus_tag="KRH82_000528"
     CDS             71245..72030
                     /gene="aroF"
                     /locus_tag="KRH82_000528"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBG8653828.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            72285..74075
                     /locus_tag="KRH82_000529"
     CDS             72285..74075
                     /locus_tag="KRH82_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBG8653829.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            74093..75259
                     /gene="rpoD"
                     /locus_tag="KRH82_000530"
     CDS             74093..75259
                     /gene="rpoD"
                     /locus_tag="KRH82_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBG8653830.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            75424..76113
                     /locus_tag="KRH82_000531"
     CDS             75424..76113
                     /locus_tag="KRH82_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBG8653831.1"
                     /translation="MKLTDRLLKIASLASDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            76127..77224
                     /locus_tag="KRH82_000532"
     CDS             76127..77224
                     /locus_tag="KRH82_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBG8653832.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            77287..77859
                     /locus_tag="KRH82_000533"
     CDS             77287..77859
                     /locus_tag="KRH82_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBG8653833.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKMGIRDYLKRLNI"
     gene            complement(77919..78386)
                     /locus_tag="KRH82_000534"
     CDS             complement(77919..78386)
                     /locus_tag="KRH82_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBG8653834.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(78772..79248)
                     /locus_tag="KRH82_000535"
     CDS             complement(78772..79248)
                     /locus_tag="KRH82_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBG8653835.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(79368..80459)
                     /locus_tag="KRH82_000536"
     CDS             complement(79368..80459)
                     /locus_tag="KRH82_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBG8653836.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFMPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKKFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKLEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(80452..80841)
                     /locus_tag="KRH82_000537"
     CDS             complement(80452..80841)
                     /locus_tag="KRH82_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8653837.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            81033..81479
                     /locus_tag="KRH82_000538"
     CDS             81033..81479
                     /locus_tag="KRH82_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653838.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            81743..82468
                     /locus_tag="KRH82_000539"
     CDS             81743..82468
                     /locus_tag="KRH82_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8653839.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            82455..83699
                     /locus_tag="KRH82_000540"
     CDS             82455..83699
                     /locus_tag="KRH82_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8653840.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFTSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            83779..84456
                     /locus_tag="KRH82_000541"
     CDS             83779..84456
                     /locus_tag="KRH82_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653841.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            84457..87018
                     /locus_tag="KRH82_000542"
     CDS             84457..87018
                     /locus_tag="KRH82_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653842.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEHKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            87239..88513
                     /locus_tag="KRH82_000543"
     CDS             87239..88513
                     /locus_tag="KRH82_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8653843.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSINDK"
     gene            complement(88674..91715)
                     /locus_tag="KRH82_000544"
     CDS             complement(88674..91715)
                     /locus_tag="KRH82_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBG8653844.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNVFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            91922..92221
                     /locus_tag="KRH82_000545"
     CDS             91922..92221
                     /locus_tag="KRH82_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBG8653845.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            complement(92459..94687)
                     /locus_tag="KRH82_000546"
     CDS             complement(92459..94687)
                     /locus_tag="KRH82_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBG8653846.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNNTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
BASE COUNT        36204 a        10945 c        14644 g        32993 t
ORIGIN      
        1 taacttttta gctataatta ttattgttat taattgaaaa gatttattag ttacttgaca
       61 tagtttacac ttttaattat agtataaatt ggaatattta gataattatt atttaatgta
      121 taagctaagt ttttaattaa tatggcttta tacatttata tagaaaagag gtacgtatga
      181 gtagcacaat caaatcaaat cgaataaaag gtataatgtt tataatagca tcagcgcttg
      241 gctttgcaat gatgtctgca ttcgtaaagc tagctggaga tttaccaagt tttcaaaaag
      301 tgttctttag aaatctggta tcagctataa tagctttttg gcttatcata aaacataaag
      361 gaagtctaac tggtaaaaaa gaaaatttaa aagtactttt atataggtca atatttggaa
      421 ctctaggagt tatatttaac tactatgcaa ttgacaagtt gatgctttca gatgctaata
      481 tgctaaataa aatgagtccc ttccttgtag taatattttg tgcaattgct ctaaaagaaa
      541 aaataaatgt aaagcagata ggagctatta taattgcatt tataggagct ttattcataa
      601 taaaaccaac atttagtgta gaagtaattc catatcttgg gggaattgca ggagctgtat
      661 ttgcagcaat ggcatatact tgtttaagag ttcttggaga tagagaagat tactatacaa
      721 ttgtattttt cttttcagtt ttttcattag ttactgtagg gccaattgct tttgcagtat
      781 atgaaccaat gacccttatg caacttatat atctattact aggtggagta tttgcaagtc
      841 taggtcaatt tggaataact ctagcatata aatatgcacc tgctaaggaa atctctatat
      901 ttgactatag taatataatc ttttcagcaa ttttaagtat attcttattc aatgtctatc
      961 cagatatgtt aagtgttgtt ggatatttaa tagtattttc ggcagcattt tatatgtttt
     1021 tatacaataa gaagttagat aaattagaca aagaaaagaa gaagtaaact agataaaagt
     1081 gtttttataa tttgtattga atatttaagt ctttgtatta aaattaaaga aaatttaatt
     1141 aaaaatgttt ggtatattaa cttataacag cagttaaaat tgaaaaatta taactgctgt
     1201 ttcttttatt aaaaatatcc aaatgtctgt aaaaatagac tataatagag tagtataaat
     1261 aatataaagg ggataaatta aagtatggaa aaagtgaaag ttgctgtgat tggagcaggt
     1321 aatagaggaa cgtatgcata tgctccatat atttatgaaa attctgatgt atgtgaaata
     1381 gttgctgtag cagaacctaa aaaaggaaga cgagaactat ttacaaaaaa atataaccta
     1441 gatagtaaaa atgtatttga aactttagaa gactttttta aacatgacaa gatggcagat
     1501 gcagtaataa tagctacaaa tgatgataga cattatgatg tagcaaaact agctcttgaa
     1561 aaaggttatc atgtactatt agaaaagcca atgtctaata gtttagatgg tttggtacat
     1621 atagatgact tgtgtgataa gtataaagat aagattttta tgatttgcca tgtactgaga
     1681 tattctccat tttataataa attaaaagaa attgtagaaa gcaaaaaatt aggagagcta
     1741 gttagtatac aatataatga aaatatagga tattggcatt ttgcacatag ctttactaga
     1801 gggaattgga gaaatagcaa tgaaaccagt cctttaattt tagcaaagag ttgtcatgac
     1861 atggatattt tgttatattt agtaggaagt agatgcaaaa aaatatctgc atttggaagc
     1921 ttaaagcatc ttaataacca aaatgctagt ggagagatgg cacaaaattg tcttcagtgt
     1981 ttagttgaaa aaaaatgtcc atattcagca aagagaattt atttagaaaa agatagaagt
     2041 ataaatagag ctgttcacat aaatccaact gaagagaatc tattaaatat acttaagaca
     2101 agtccatatg gaagatgtgt ttacagatgt gataataatg ttgtagacaa tatggtaaat
     2161 atactacagt ttgaaaatgg agtgacggct acttttaatt tatgtgcatt tactaaagaa
     2221 aatggaagaa ctataaagtt aatgtttagc catggtgaag ttggtgggga tttaaataaa
     2281 aatgagataa gaattaaaga atttggaaaa aacgaagaaa tagttatgaa tccatcaaat
     2341 caacagaata tggtagagga atatgataga aatcttatag ctgaatttat taaattagtt
     2401 tcaaataaag aactagaaaa gggtagagta gcagcaaaag aagctataca aagtcatgta
     2461 atggcatttg cagcagaata ttctagggtc agtgatgaag tagtgtatat agaagaattt
     2521 tttgatagtg ctaagcaaat gactaaggag atagaagaaa ctatatttta attaataaaa
     2581 atttattaaa taaaataaag atagattaaa taatagaaat acgaaaatat gtgttctatt
     2641 aaggaatcta tcttttttat taaggttttt tcttatccct atcaaaaaaa tccatacatt
     2701 ctgataaaag ataagaaagt aaagcgaata agatttctgt acttaaagga atcgttactg
     2761 aatccataaa ggtatcaatt atgttcatag ctagaaaagt tagtataaaa tcaattataa
     2821 attcgcaaag tttatatatt gagtatggta atttgtttac atatctgaat atatctaaaa
     2881 tagtagtgca tagaaaatca attggagtgg ttatacaaaa atatattaaa aagaaaatta
     2941 atacagctcc aagagattta tattcaaatc ctaagaatga taagaagcca attcctataa
     3001 ccgtgaaaat acaaaaagtt ataccaaaaa aaacagcaaa aaataaaaat acagaaataa
     3061 attcgcctaa aggaatcctt cttttattac ttatcttaat caactcctta atttatgata
     3121 tgaaatttat ataaataata acattcttaa aaattcataa tagtcctctg tttcaaatag
     3181 tactgtttga gaatctattt ttttcatatt tggataaaaa gaggccttaa aagctttata
     3241 atgttctcta aattttattt ctatcttaaa tttatctggc aattttatta agtgcctaga
     3301 taaatctcca gataaagctt ttttgacacc tttttcaatt ttttttagtg caaggtttgg
     3361 atggattgaa attgaaccat ttccaattcc ttttgacaca ggaacagtga ctatatttgg
     3421 atttagtttt tttgcactct cacaaagcat ttcatctcca cttaaaaatg ctacaggaac
     3481 attataatat gcagcaatat aagcatttat agtaaattca gatgctattt catcatttat
     3541 tttaaaatag tcataatcaa tatccatagt atgagaaagt ggattaccat tacaagtagc
     3601 tccagagtga tagccggtga atatacatgc atcaaagctt tcatcaattc ctgccatcat
     3661 aactagtggg tctttggtcc atcctctaag tattttgacg ttttcaggta aaatatttgg
     3721 attaatattt ctaccactgt catgtgcatc tttaacaagt atttcatgta caccagattg
     3781 agtagctcca tcacatgctg ctgttatctc tttactcatt tgtgttctat agtgttgcga
     3841 aaattcacat tcaagttttg tttcatccca atttacaata ccacaagtac cttctatatc
     3901 agcacttaaa tacaatttca taatatatac ccccttatgt ttattattga tgataataac
     3961 agataacaga aaatacataa tcaataaagg gcataaaaat attatgtctt actattaact
     4021 attattaaat ctgtaactga aaaataacta aattggtata aaaaaatata acactatgtg
     4081 tcatttattt atatagtttt ttatatttga tgtttatata aaattgtaac atataagtgg
     4141 ttacatttac tagtttaaca tagttaaaat agttaggtat tatttttaag ttaaattgat
     4201 tattataaaa tcgcagaata aaagaaaaat ttaatttatt aaaatgcatg aaatgttttt
     4261 tcctcaacat aatgctaaat taaactcaaa aagaaataat agaaaaatct tatgtagctt
     4321 agaaagaatg tgaatgattt aagggaaaaa tagaaattta ttatataata ttaggttgta
     4381 ttatataata cagcctaata ttatatgtat atgtgacata aaatcttggt aagtgtaaat
     4441 aaaataaatg tggaaaacaa gttaatgaaa tcaagaaaaa agtaatttaa aattcaattt
     4501 catcttccca attaaattct cctgattttt ctacactctt aggccagtga ctacaccatt
     4561 taggaacgga cggattttca accctatcaa cgcttggagt atatggcttt aagtcaataa
     4621 caggactatt atcattagca tcaatatatg gtatttttat tatgccattt tcatggtcga
     4681 tattgataat ttgtacagca gtcaatgcta ttggattggg tcttataggt gaccttgttg
     4741 caaatattcc tataacgtct ggtccacttt tataaggttt tggggtttct aaaatacttc
     4801 ttagttcagg attatcaaac ccatcagccc accaaaatac atttaaatga ctgaaatcgt
     4861 cgagttcatt taatgcaggt acatactttt tgtctaattt aataaagacc tcttcgcctt
     4921 gaatacatat tttacctata ggatttatta atatttcttt cataatatta cctccaacta
     4981 tttaatttat catttgtaat tttagggtat aacatgacat catgtgaggg tcaatataaa
     5041 ataataaata aaaatattaa tagttagaat gataatacat tttttacatg gagcatgaca
     5101 ccagtaataa ggcaatcttc gtcaatatca aaagtagagg tatgcaaagg ggaagtaatg
     5161 tttttttcac gatttgcaca accaaggtgg taaaaagctc cttcacagtg tcttagaaaa
     5221 tacgaaaagt cttcagcccc aagagtgggc gagtctttaa ggataatatt ttcttcacca
     5281 aacaattcta cagcattttg tttgacgtaa tctactagat ggtttgaatt gataagagct
     5341 ggataacctt cctcaatttc aacagaaata cttcctccaa atgttttaca agtaaaatcg
     5401 caaatttctc taattcgttt ttttgaaaac tctctagttt caggagtcaa ggttctcaaa
     5461 gtacccctta taaccacttt gtcacaaact atattttctt tgattccacc ttcaatcttt
     5521 cctagagaaa taaccacaga atcagttgga tttgtgtttc gactaacgat tgtctgtaga
     5581 gctgtaataa tatgagcaga tataacaata gcatcaatac cttgatgtgg ataagctcca
     5641 tgacattttg aaccatgtac agttaattga agtgtatcgg tggaagcatt tagagtgttg
     5701 tattttaatt caattagatt tttgttgata ttgggattta catgaagtcc aaatatatat
     5761 tttacatttg ggttttcaag acatccatct tctatcataa gttgagcccc accaatagtt
     5821 tcctcggcag gttgaaaaaa gaattttaca tttacattta agtaatcctt taatttaaat
     5881 agtatattac aagtacccag taaaatagca gtgtgtgcat catgaccaca tgcatgcatt
     5941 ttgccaatat taatagattt ataagaataa ttaagttctt ctgttatagg taaggcatct
     6001 atatcagctc ttatagcaac tgtttcaaag tttggactca cgttaatgta tgcagttatc
     6061 cctgtatgat tcttatattc aatataattt atacctattt catttaagta tttaataatt
     6121 tttttcttag tttgaaattc ttctaatcca agttctggag tcttatgtaa atctcttctt
     6181 atatttataa cccaatcatt tatctcatga caaagagttt ttatattaag cataaaacac
     6241 atcctaacta tattaaaaat ttatttttct tcattaatta tattatttta tgtaaatcat
     6301 tattatgtat caagtacaaa taaaatatct tataattata ttagagatat ttagtatgga
     6361 gaagaatata tcattttata agaagaggtg tttaaatgtt aggaataatt gcgccatctg
     6421 ggccattaag aaatacaagt ttggaggaaa taaagtttaa tttagaaagt tatggttacg
     6481 aagttaagtt ttctgaaagt tgtagtttaa attataaagg ttatttagct ggtaatgatg
     6541 atattagagc aagggatata gaagatatgt ttttagataa agatgtagat ataattatgt
     6601 gcttaagagg aggttatgga acaacaagaa tattggataa aataaattat gatataataa
     6661 agcaaaatcc aaaaccattt ataggttttt ctgatataac aggtttaaat ttagctttct
     6721 ataaaaattg tggtctttta ccatatcatg gaataatggc agcaaatgta ggtaaatggg
     6781 ataaatttac ctataaatca ttggtaaatg ctttagaatt taaagatgaa ttatatttag
     6841 aaaatccaaa agaagaaaag atttatactg tatgtgaagg taaagcagag ggaataataa
     6901 tgggaggaaa tttatcctta ataattgcca caatgggaac aaaatatgaa atagatgcaa
     6961 aagataaaat tttgtttatt gaggaaattg gagaacctca atataaattg gatagaatgt
     7021 taacacaact atattcttca ggaaaacttg aggaatgtaa tggtataatt tttggagatt
     7081 ttaaggattg tattgaagaa aatgatttga tggaattact aatagaattt gcaaataagg
     7141 tcaataaacc ttctatatat aatcttcagt caggacattg tatcccaatg ataactattc
     7201 ctttgggcag aatgtgcgaa ttagatgcta cagaaaaaat cgttaaatta aaaaaatagt
     7261 gtgtatataa atataataga aatatggtat aatcttatac aagtaaaaat ttagctagga
     7321 ggatgaaaaa tgtctgatga tagaataata gactttaacg aactaaagaa caaagttaaa
     7381 gattctgatg tagataaatt tgagcaatac atatataact tatatttttc tgttatggat
     7441 ggaaagatgt ctatggctga gttttcaaga aaaatattcg attatatgag agataacaac
     7501 atatctcaag aaaaatttat gaaaatacaa aagcaattta tggagagata tggtatggac
     7561 actgaagaag tagaaaaaca acttagaaac tttggaatcg acccttctac agcaggtttt
     7621 atgagtaata atacttccag caaagtatct acagaagatt tagagtcatt taagaagagt
     7681 gcaggatttt atgagaaata tggagaaaaa atccaaccaa agagttgtat aacaacattt
     7741 ataaaaaatg acttaaatga tattaatgta ataatcgacc aagaaaagat aatgctttgt
     7801 agtgatagaa aaataaatct tatggattca gaactaaatg agtttttatt agaatataag
     7861 aatatgttta ataaaaaaat aaaggtagta atgtgcgaaa ctacgaataa gtatgattat
     7921 taaaaaatga atttaaatac tgaagtagta tcaattaatt gtactactta aaaataaaaa
     7981 tcgcaattta ttattcctta taaatttgta taaggaatat ctaaactgcg attttttata
     8041 ttgtgaagat tagtaataat agatagtgtt ttaaattgta atcttctcac taaaactgtg
     8101 tttttctatt agaaatttta ttaaaaataa atatctgata attgtattat atgggatgta
     8161 aagtattaga agcttaacga atctctttta atacattaac tccattttga atcatactgt
     8221 tgaaaaatac taagtttaaa atctcagcag ggtgaacgtt aggaatatca taagtatcta
     8281 ctaaattcat aggtacaact atattttttt caatattatg ttgattaaaa tatgatttta
     8341 gagttattgc aaattgatat atacatatat ctgtgcaatc gccaactata attatattat
     8401 ctatattatc aaaatccaaa ttttctaatg caaaaaaacc attagtagaa tttttaggaa
     8461 gaatttgtag gttttctatc gacttaagtt catcaaccaa ttcactttct acatcatttt
     8521 ccaaacagtg aacaggataa ctcaaaagtt ctattgattt aggagtatga gaatcagtaa
     8581 atgctattac tctatttaat ttgtttgata ttttttttgt aaacatttca attggcttta
     8641 ttaaagactc tactctagga gagtataatg caccttgtct tgcaaagcca ttattaacat
     8701 caattataaa taaagcagtt ttactcaaat cataattttc tattttttct attggtagat
     8761 tatctaaatt actctttaaa gcttcaagtt catttaataa gttatccata gttatacctc
     8821 caagataaat ttaataaaat tgtacatatt aattatataa aagtcaagga gtacaaacta
     8881 ttgtataatt agctgtattg ttttgagtgt aaaagatttg aagcaatatc tggatagtta
     8941 gtaaaaatac catctacatt gagttttaga cagtgtagta tatcatcctc ttcatttaca
     9001 gtatatacat tgacaccaag tagatttttg tgacaaagtt caattagaga ttcatttact
     9061 aaaactagag gtggatgaag gtaactatta cccagaaatt tagcaaaatt gactacattg
     9121 tttataggta aataacacaa taatcctgtt tttatactag ggtctaattt atgaaagttt
     9181 tttaagctat tgctgttgaa actagatata agaactctat ttttcatatt atactttaaa
     9241 ataagctcta aaacgtcttt ttctatattg ggatagttta ttttgtcagt ttttagttct
     9301 atatttaaaa taaggtctgt aggtgaaatt agaattaata cttcttctaa agttggaatt
     9361 ttacattctt tattgctttg atatccttca aaagatgagt ttagagtttt taattttctt
     9421 aaagtaaagt cttttacaaa accatgtcca ttaaaagttc tatcaacctt ttcatcatga
     9481 ataactacaa tttttccatc cttagttctg tggacatcaa gttctattcc atatatatcc
     9541 atatccaaac attttttaaa agctagaata gtattttctg gatactttcc actaaacccc
     9601 ctatgagcat aaatattcat ttatatggtt ccctcctata agtataactt atcttataaa
     9661 aatttaatta atataatata tcatattcca aaaggtattg ttatatatta gttaaataac
     9721 tatttgtaat ttatatatta tataaatgta gaaaaataaa atcatatatg tgttataata
     9781 tattttaaac attgtaaata ttacgaattt agtagtcata ataagtgtaa ttttatgcaa
     9841 gctcatgttt ttagagcttg catatgtatt attaatatat ttatatattg tgaaaataaa
     9901 attccaaaag aattttttct atagacttag tagtaagggg gaattttgat atgtatgaag
     9961 ttaatttaga acgagctatg aattattgga tggatttgtt agatgattat acgaatatag
    10021 caaaaattcc aaatgatttt ttttataaag attgttctga tgaagtagta gatgaggttt
    10081 ttaagatgaa tattgagaaa catgaaaggt taattcaata ttctaaagtg aacaatatta
    10141 gcatagactc tatcatagaa actatatatg gccttatact tcaaaagtat atatatgaag
    10201 atgatgtagt ttttggtaaa acaatgaata taattccaat aagagtaaga gttagacaaa
    10261 gtgaaaaatt tatagatgtt gtaaggaagc taaaaaggca gtggagcagg tctttagagt
    10321 atggatacta tttgttatca gatatagaga ataaaaatca tctaaatact aagcttataa
    10381 acacaatatt tatagctaaa agttttgatt tatcatatga ttatgacata gaaaaaaaag
    10441 gatatgattt atctgtaata gtatatacta agagggcact taaaataaaa ataaagtata
    10501 aaccatctat atataaaaga gaaactatta gaagaatttt aaatcaattt gattatataa
    10561 tagagcaaat aatagaagat aatgatattt taatagaaga tttagaattt gtatgtaagg
    10621 aagaagaaaa agtattattg gaagacttta ataataatca atatgaagta ccctatgata
    10681 aaagttatgt tgatttattt agggagcaag ttaaggtaac acctagtaat atagctgcta
    10741 gggatgaaaa tagaaagtta acatataaag aattggatga agtaactgat aaacttgcag
    10801 gttatttaaa tcatatagga gtggaaagtg aagacatagt agctgtaatg ttaccaagag
    10861 atattaacat aattattaca gcaataggga ttatgaaatc agggggagca ttttttccaa
    10921 tagacacaag taatccagaa gaaagattga attaccttct tgaagatagt aatgcaaaag
    10981 tagtgataac tacagatgaa ctcaaaagta aggttgtaaa tgagaatacc atagtactcg
    11041 atataaatga tgaagaaatg tttaagcttg gatatgaatt aactgaaaaa ataacatcat
    11101 caaattgtgc atatacgata tctacttcag ggtcaactgg taggccaaag accatagcta
    11161 tagaacataa gagtttagta aatatgtgtt attatagcgt aaaatctata agcgctacag
    11221 aaaatgatat atgtggtata tacttaagtt tcagttttga tgctgtaatg aaacaactat
    11281 tcccttattt gcttgtaggt gcatcaatag atattatgcc tgaagaagct aaatttgatg
    11341 aatatacagt aaatgaatac tgtgaggaaa atgacataac tatactagca ttgccaacag
    11401 catttgcaag gttatttata caaaattgca ataataattc acttagagtt gtacagactg
    11461 gaggagaaag attaaaagga tatagaaagc gtaattatga actatataat gagtatggac
    11521 caaccgaatt tactgttgta tcgacttctt ttcatgtgga cagagaatat ggaaaaatac
    11581 caataggaaa acctatattt aatacttatg catatgtatt agataaaaag aacaaactat
    11641 gtccaattgg agcaccagga gagctatgtc tatcaggcat tcaaatatca agaggatatt
    11701 taaataaaaa agggctaaca gagcaagtat ttgtagagaa tccttacaaa acttgtgaac
    11761 ataataagtt aatgtataga actggtgatt tagtaagatg gttagatgat ggaaatttag
    11821 attatattgg aaggatggac aatcaagtaa aaattgatga gtttaggata gagctatatg
    11881 agattgaaaa tataataaat aatattacag aaattaaaag tgttgtttgt atatcgagaa
    11941 caaatgatga tggagatatg tatatatgtg catattatgt aattgatgag gaagatagtg
    12001 gtaagataaa tgaaagaact attagagaat atttaaatga gcatctacct ccatatatga
    12061 ttccaacaat aataatgagg atagataaga taccagttac accaatcgga aaagtaaata
    12121 aaagagcatt accagaataa ttttttatta tgataggtgt cataaagtga tttcagacat
    12181 ttctttatga cacttatttt tataaaagaa tcaatttgca taaaaacaag aattttctgt
    12241 atatatttac tatggtgaaa atttatttat aagaatgatt attgtatttt ttatactttt
    12301 ccgtgtttta aagcattttt tttacaaaat taattttaca ttaaaaaatt tttttatttt
    12361 atatcttaat agtttttagt agaattgaaa aataaaaaga aaattagcat aaaaatatct
    12421 aaaagtagaa attaataata tagggttaaa ttttagtagt tttgactcgc tatttgtaaa
    12481 ataataaaaa gttaagtttt atatgtatat atgttataat atatacaaat tgaaaagggg
    12541 tgaaaatttt atgaacaaaa aattacctaa gggtgcttat ggtgaggtta gtggaaaaga
    12601 ttacgttcca tatatcacag ataagtccag aaccggtgga aatgtagctg tactgattat
    12661 cggtattatt ttagctgcca tttttgccgc atctacaact tactctggaa tgaaagccgg
    12721 tcttacagtt gccgcaggta ttccaggagc tataataggt tctgcttttg ttggagcatt
    12781 tgctcgttca aagggtattc ttggtaaaaa cttaatccaa ggtatgtcaa gtggtggaga
    12841 atctgttgca agtggattta ttttcgtatt accagcagtt atattaattg gaagccaaat
    12901 tacattctta gaaggcttag ctgttggagt tggtggagtt ttatttggta taggaattgc
    12961 tgctatagtt cacaactatc taatagttga agaacatggt aaacttatgt acccagaatc
    13021 aatggctata tctgagacac ttgttgcttc agaggctggt ggagattcaa ttaagtacat
    13081 gggaattgga tttgtaataa gtggatttat tactgtatta actggttcat tcttaaatgt
    13141 agcaaacaat gtaatgagtc ttgtaggaag caaattctac aaatggaaat ttgatattga
    13201 agtaaatcct ctacttttag gaattggatt tatagtaggg cttgaagttt ctttaacaat
    13261 gtttgcagga agtattttat caaactttgg tatagcacct ttaataggat actttacaga
    13321 tatggctaaa gatggagcta tggtatggaa taatcctgca atgcctctta accaaatgga
    13381 tgttggagca atatctagta gttatgtaaa atatataggt gctggtatga tgctttgtgg
    13441 aggtattatt ggtgcaataa aacttatacc aactataatc gcttctataa aagaaacact
    13501 taaagctaaa tcaagtgctg gagaaggaga agaaggttca tctatacaaa tgatactttt
    13561 attaggtgga gtagttattg gatttttagc agcattctta atttctggta acattgttat
    13621 ggcaattatt ggagctatca tatctctttt attatcttta ttatttgtca tagtagctgg
    13681 tcgtttaaca ggaacaatcg gaacatcaaa tcttccagtt tctggtatga ctatagcttc
    13741 tctagttatt gtaacattag tgtttgttat aatgggatgg actgatttag aagctaataa
    13801 atcattactt ttatttggtt catttatagt tgttgctatt gctatagctg gaggttatac
    13861 tcaatctcaa aaagtaactt atattattgg tggtagcaaa aacgaaatgc aacgttactt
    13921 tacaattgca agtatagttg gtgttatagt tgttgtagga gtaattttat tactttctga
    13981 ccaacttaga gcaactggtg ataatgtaca atttgcatta ccacaagcaa acttaatgtc
    14041 aacattaact tctggtatta tgtcaggtag tttaccttgg gttatgatta ttgttggagt
    14101 atttatggca atcgttctat atgcattaaa tttaccaata atgactatag ctataggatt
    14161 ctatttacca attgcaacaa cttctataat attagttgga gcattaattc gtttatttgt
    14221 tgaattagta tctaaaactg aaaaagaaaa agaagttaaa gtttctaatg gtataagttt
    14281 atcttctggt cttgttgctg gtggttctat cattggttta ataggtataa tattacaagt
    14341 aactggagtt gtaactccaa aggtaccaag tggatttgct gcaacaaatt caatggcaat
    14401 tgctttatta gtagttttag ttgtgcttac agcattacct attgttttat ctaaagtaaa
    14461 aaataatgag caagagtaat gatgttttag atattgtatt taaaattact gatggacttg
    14521 aatatgaagt agctgaaaat agtgttgtta ctatacttga aaaacaggac cataaaattc
    14581 aaaagttttt tagaaagtta aaagctagaa tacctaaata caaaaaaata gaactagatg
    14641 aatattcaag ttttgttttt ttacaaattg atggtcaaag gactgttaga gaaataggca
    14701 agaacctaga agctaaatat ggagaagaat ctcatccact ttatgaaagg ttgttagtat
    14761 ttttaaatca tattgaagtt aattgtcact atattgaaag actggatata tagatataat
    14821 aagaattatt atagatatat tagagcatat aaattagaag gtaattatga aagaggctgt
    14881 ctcaaaatag agataagcct cttttgtatt gttgaaatga tgaaaatata tttgatttct
    14941 cataaaaaag agtgtctcat aaaactaaaa agttcatttt gagacacttc ctttaaaata
    15001 tttataaatt acagatttaa agcaaaactt attaaactta agattatttt aatatcactt
    15061 attattagct atttcatcag ctagattatt taaatattcc catctttcat atttgtattc
    15121 aagttctttt tctagtttag atttctcatc taaaatttct tggagtttag taaaatcagt
    15181 tgaaaatttt gcagtacttt catcaagtgt tgcaatttta gattcgagtt tttctatatc
    15241 agagtcaata ttttcaaact ccctttgttc attatatgag aacttaagct ttttatcatt
    15301 tttaggtttt tcttttttta gggtagtaga gtcatctttt ttaactgatt cccttttaga
    15361 ttcttcaaat tcaattcctt gaatctctct ataaataaga taatcactgt aattacctgt
    15421 atagatatga atttttccat taccttcata tgcaaatatt ttattacaaa ttctatctaa
    15481 gaaatatcta tcatgtgata ctgtaactac tacaccttta aattcgtcta ggtattcttc
    15541 taatatttta agcgtttcaa tatctaaatc atttgtaggt tcatctaaaa gaagcacatt
    15601 aggagctgtc ataaggattt taagaagatg tagtcttctt ctttcaccac cagataattt
    15661 acctatcaaa gtatattgca tagtaccatt gaaaaggaat ctttcacaca tttgagaagc
    15721 tgtaatccta gtaccatctg aagtttctat atagtcacta gcttctttta catagtctat
    15781 agccctcata tcaatattca tatgagagtc gtcttgagaa aaacaaccta ttttaaccgt
    15841 ttctccaatt gaaatatatc cactatcagg ctctatttct ccattaagta tatttataag
    15901 ggtagattta cccataccat ttttgcctat tataccaatt ctatctgtac gagttaaagt
    15961 gtattctaaa ttatctataa cagtattttc ttcaaatgat ttagatatat tgtgtatttc
    16021 tattatttta tttccaagtc tacttgatgc aacagatata tcaagatttt catcaggttt
    16081 aaaagaatct ctatttataa gttcatcaaa tctttgtaaa cgagcttttt gtttagtgct
    16141 acgagcctga gctcctcgtc ttacccacgc aagctctgtt cttattaaat tttgtctttt
    16201 atcttcaata cttgcttcta gcgaaagtct ttccattttc ttttccaaaa atattgaata
    16261 attcccatca taactgaata atctaccctt gtccagttca ataattctat ttgtaacacg
    16321 gtctaaaaag tatctatcat gagttatcat aagcaatgaa ccttttctgg aattaagata
    16381 ttcctcaagc caatctatag tatcattgtc tagatggttt gtaggctcat ctagtatcaa
    16441 aaactcacaa ggtgtaataa gggctgatgc cagagagact ctctttcttt gcccaccaga
    16501 aagttctgct attttttgat taaagtcatt tataccaagc tttgtaagta ctgacttagc
    16561 ttcactttct aaatcccaaa gatttaaggc atctattttt tcgtgtactg ataataattt
    16621 tttatttaat tcctctgtaa agtttgaatt aagtttttct aggatttctt gatattcacc
    16681 aagtagcttt aattcttcag aagttccatt aaatacttgt tcaagtacag ttgaattttc
    16741 attgtaagtt ggattttgag gtagatattc tatcctaata ccattagttt ttgttatatt
    16801 accagtttca ctttcttcaa ctcctgcaat aattttgagt aaggtagatt taccagtgcc
    16861 atttacacca ataagtccta ttttttcccc ttcatttatt ccaagagata tattttctag
    16921 taattttttt tcagaatagc ttttacttat attttccaat gtcattaaat tcatataatt
    16981 cacctttatt tctaatctat tatttttcaa aatgttgata atctgggttt ttccaatagc
    17041 caccccaact ccaacctctg cttacaaaag cattataaca atcatcacct ttttttatca
    17101 ttccaaattt tgtgctagac ctatcagcat aaactgtact tactttaggt gtaacatcat
    17161 ttccagaaac ttgaggattc tgtaatgggt ttatatctat agcacgtcct ttaccatgat
    17221 ttgaaactac atttgtacca gctatagttc tataacaaaa tgatgaggta ttattatcag
    17281 acatagattt ttcatctaca gcatcatagt catctattaa cttaattttt tcaattggat
    17341 attttttttc gtataattcc ttaaaaatat ccactacttc tggagctagt tcactgttta
    17401 ctatcatttc tccttgatga gttttttcat caaatccata atatgtaagt tttaaataag
    17461 atagactatc aaagcttata ggttcatcag taggcataga tttaccaatc attttatttt
    17521 ttatattatc tggtattgaa gaatatgaaa aagtaggctt gatattatta tcttcctgct
    17581 ttttggtaga gctttgatta tttttagaat catctgttgt attattttta ttttgcatag
    17641 tttcttgact ctttatatta ccttttttgt tgggattaga gaacagtatc tcatatatag
    17701 ataataaagc aagaaataat acagttatta caatcgttaa ttttaattta ttaatttttc
    17761 ttcgttttga ctttttactc atattatccc ccagtattag attcatataa actatatata
    17821 ttatacctca taaaaataaa ctaggctaac aatatttagt taacctagaa catttcattt
    17881 atagtttctc caattatttt tattccaatt tcaatgtctt caaaagacaa cctagaaaat
    17941 ccgagtctta aagtatcaaa accagagtta tctgtaaaaa ataagtctcc aggcataaat
    18001 ataacatttt tttcataaca tttttctaat aaaactctag tatctatatt ttttagtttt
    18061 ataaatatat gcaaaccacc atcacccaag atatattctg tttttatata tttttttata
    18121 catttatatg caaagttaaa tttgtctcca tagaatttac gtattttttt aatgtatttt
    18181 tcaaaacctc cattacttaa ataatcaaat aaaattcctt ggtctaaaaa ggatacatgt
    18241 atgtttctgc acctttttac actttctagc ttattgatta cttttttatc tgcaaatatc
    18301 catccaattc tcattccagg aaataaaatc tttgaaaaac taccaatata tacgacccca
    18361 ttattcatat tatctaggga acagatagga aatatatgag aactattgta gagtaattct
    18421 tcattaaatc catcttctat agttgctata ttgtattttt tcataagatt atagaatttg
    18481 tacctatttt caggagtcat tacaattcct gtaggattgt gataagaggg tgtaatgtat
    18541 gcaaacttta ttttattttt atacttaact aaattgtctt ctagcatatt gaagtccaaa
    18601 ccatcttcat ttatatctac acctaagata ttgaggttat gagatttcat aatttttata
    18661 gcagtattat gagtaggatt ttcacatatt atgtagtctt tttcttgggt aaaagatgac
    18721 ataataatat caaagccttc tgtgaatcca tttgttatta gtatatcttt attacttata
    18781 tcagcaccct tgtttgtcat atattctagt aaatagtcaa taagtggctt ataaccttgt
    18841 gcatatccat agttgagtaa tttatgtcct tctagtgaaa ttctatttaa aaaggatttt
    18901 tttaattctt ccatgtcgaa taaatctcca tctggagaaa tacttttaaa ggaaatcagg
    18961 tcagagctcc aaggaatttc actttttata atgtccaatt cattggcttt tttagagtat
    19021 gtattctcta aacaatccca gtttaatgac catgtagtat ttgaagactt attctttgat
    19081 ttaacaaatg taccttttcc tgaaatagag tagattaatc cttctgattt taattcttca
    19141 taagttaaaa ctacagaatt tcggctaact tgtaaaagct gactaagctc ccttgtagaa
    19201 gggagcttac tattgtctgg aattagtcct tttgatatca tatcacttat ataattttta
    19261 agttgtatat aaattggttc attatcattt aattttagat ttgaaaatat caaattacca
    19321 cctcaaatta tttcatctaa tttaaagagt attctataag tttatctaat agttcactgt
    19381 acttaatacc tctagcagca gcacttctag gaattaaact agtttgagtc attccaggaa
    19441 gagtatttag ttcaagaaca tatggaatac cttcacttat aatcatatca actcttacat
    19501 atgctttgca attaaaaatt ttccaacaag tctcagaaat ttcgtttact cttttttgaa
    19561 gttcttcatc taagtaaaca acttcttcct ttgcaccttt ttcaactgag tatttagctt
    19621 cataatcaaa gaatcctgaa tcagatttta tagatattgt agggaatact tctccattta
    19681 atatgaatga agtatattct ccacctggta tatatttttc aatcattaca aattcatcaa
    19741 cttccagacc ttttctaact gcttcttcaa cttcatcctt agaatgaata aagaatgtgg
    19801 ctacacttga acctcctgag tttggtttta taaatactgg ataacctata ttatctattt
    19861 catcatagtc tatttcatca actgatttta ctaaaaccca tggagcagta ggtaggtttg
    19921 aatctctaag cattttttta gttatatttt tatccataca catcccactg caaagaggtc
    19981 cacatccaga gtatggtata tccatagtct caagtattga ttgtatacat ccatcttcac
    20041 caaattttcc atgtaaagca agtattgcaa aatctatatc ttctggtatc tttgtaaata
    20101 tatctttttt atcatctatt attactttta caacttcata tttattttta tcaaggttat
    20161 tatatatctc ttttcctgaa tttaaagaaa cttctctctc tgatgatatt ccacccatta
    20221 taactgctat tttcatatta tacactccta ttttaatttt tattatttta aagtaaactt
    20281 tttatttaca tacttaatta tatgaattaa cagttgagga tgaaagtacc actatatacg
    20341 aagtttatat tatgtgtggt tttagaataa taatctagtt taaagatatg tttaaatgat
    20401 tttttaactt tatttatgtt attatttttg ctaaaattat tgttatgaac ttaagactag
    20461 tcttaatggc tataaatcaa ggagtgataa attttgaaag ctgaaataat aagtgtagga
    20521 acagaaatat tattgggaga tatagtaaat acaaattctc aatttttagc taaagaactt
    20581 gcatcattgg gaatagaagt ataccatcag agtactgttg gagataacaa acaaagactt
    20641 ttagaatgtt ttgatgaaag cttaaagaga agtgattttg taattactac aggtggtctt
    20701 gggccaactg gtgatgatat gacaaaagaa actgctgcag aatactttgg tcagaaatta
    20761 gaactacata aaccttcact agaggttttg gaatctttct ttgttaaaac agggaaaaaa
    20821 atggccgaaa ataatatgaa acaagtgtac tttccaaaag atgctatagt actaaaaaat
    20881 aataatggta cagctccagg ggcaatttta aaaaaagatg gtaaatttat aatagtattg
    20941 cctggacctc caagagaaat gaaagctatg tttaatgaga gtgtcaaacc ttacttacaa
    21001 caattcacaa atgaaatgct agtatctaag actttaagat tatatggaat aggtgagtca
    21061 aatctagaat tagaaattct cgatataatt aatgagcaga ctaatccaac agttgcttta
    21121 tatgcaaaag aattagaagt tacaataaga ataactgcaa aggctgaaaa tgaaagagaa
    21181 gcttttaaat taataaaacc agtagaagaa aaaataaaaa gtagagttgg taaatatgta
    21241 tatactgaag gagatatttc catatctgaa ggggagactg ctttagaaga tgctgtttct
    21301 aagctacttg tagaaaaaaa tctaacaata gcagtggctg aatcttgtac tggaggtttg
    21361 gtttcttcat ctcttataaa ctatccaggt atatcctctg tatttcttga aggttgtgta
    21421 acatattcta atgattctaa aatgaaaaga ttaggagtaa aaagagaaac tttggaagag
    21481 tttggagcag taagtgagca aacagctata gaaatggctg agggcgttgc taaaggactt
    21541 aaagctaata taggtatatc tacaactgga gtagctggac ctggtggagg aaccaaagag
    21601 aagcctgtgg gactggttta tactgcaata tatataaatg gaaaaacaat agtaaagaaa
    21661 aatatattta atggggatag aagaaagata agattaagag ctactagaga tttgcttaat
    21721 gagttgagaa tacaattaga aaagctttaa gttattttga ttaaagtatt agtaaaatat
    21781 aaaattgttt ttggaggctt ttaatttatg ataaaacata tattttgtga tttagatgga
    21841 actctatatg aaaatggaac cataacaaaa gaagatatag tagcaattga agaaatagaa
    21901 aaaaagggag tacagtttaa tgttgctaca ggtagaattt ttaaacaagc acataatatt
    21961 atcaaagata gtttagatat gaatggatat tatgtatgtg aaaatggttc atttatatat
    22021 gataaagatt ataatgtaat ttttaaaaga acgatagatg ataatttagt aaaaaaagtc
    22081 attgatagat ttgagtcaag tgatgcacaa ctttatttta aatataaggg tgatgtaatt
    22141 gtgggtagtg ataccactgc ttttagacat tattctagtg actttatagt tgacccagat
    22201 tttgaaaaaa gaagtagttt tgataatctt ataggaaata taggcgtatg ttctgaaaat
    22261 ttggaagagt tatccagaat agaactttat ctaaaaagtg agtttagtga agtcttagaa
    22321 atatattttt ctggaacata tactttaaat atagttccta aaagtgtgtc aaaaagagga
    22381 agtatagagc atgtaataaa aacgttaaat gtaagtccag atgaagttgc tactattggg
    22441 gattctccaa atgatatttg catgttagaa ggatttaaat atagttttgc aatgtctaag
    22501 gcaagggaag atgtaaagca aagtgcaaat tatgtagtag atagtgtaaa aagtgccata
    22561 gatgttataa tggagataaa tagttagtat aaaaaatgac tgtcctagag aagtataaaa
    22621 ttatattcta tagagcagtc attttaatta tattcaatta taagtttata taagtttaaa
    22681 aattcttaag ttaaccgcaa tttgctatat gatatgattt tattgtatta gataaaatag
    22741 agtcaagtat ataatttatg acactattac aagtataagc tgaaaatttt aaatcattca
    22801 tataatcagt tttctttttg taatcactat aaagtttagt aaaaaacttc tcaaaactac
    22861 tatttatagt accacattta attttagata aatcaacatc ttttgcaaat gctccaagtt
    22921 ctctttcata agtaacatgt ttatttaagc tatgcttaaa ctcccaacgt tcactgtgag
    22981 ctacacagaa aaaatcacat aaaaaatgac atatgactcc tagttcctga ctaagtctac
    23041 ttactgaaaa gtatttagaa agactatcta tattaagact gcatagatag tttattttag
    23101 aaacaatcat attaaatgac tcatctaaat aatgtttttt taatttatat ttagaaaaag
    23161 catcaggctt tatattgcca tatataaaat ttttttcgct tataaagaat gttttatttt
    23221 catctatatt atcaagtatt gattttgcca taataaaatg ggtattcatt aacatattta
    23281 cacctcgtat agtttattag acttattaaa tatattatta tgatatgata tttatgataa
    23341 aagtttaatg gtaaatatat gaaactaagt caacagtatt tatttaaata atttcaacca
    23401 tattcataat aacagtaaat ggccaaattt acaatatgta aatagtgtta agtttttatt
    23461 tatcaaattt aaaattaagt attagtatac tttctaatta acctattggc tttagactgt
    23521 gagatttcaa ggtgtttggc tactttataa gaactaccaa atttttcata agcatccaaa
    23581 attatatttt tttcatactc tttaattaaa gtgtcaaaat ttttattttt ataattagta
    23641 gattttgagt cagatataat aaccttatta atttgggata tatgtgtttt atttccatta
    23701 ttggtaatat gtatattttt tgtaagaatg tttggtaagt catctattgt tatatgatta
    23761 tctgtacaag taagcaagat tttttgaatt atattttgta attctcttat attgcctggg
    23821 aatctataat ttgcaatagc atccatagct tctttagaaa tagttttatt tagattgaag
    23881 tcacttgagt acctattaaa ataatatttt ataatttcca ctagattatc ccttctttct
    23941 ctaagaggag gcaattttat ttctataaca tttaatctat agtataaatc ttctctaaac
    24001 tttttttctt ttacttttga aactaaatca acatttgtag cagatataat tcttatatcg
    24061 acctttttat tttttaagct cccaactgga gtaaaagttc tatcctgtat taattgcaaa
    24121 aattttgcct gtagattttg tggtatatct cctatttcat ctaaaaaaag agttcctcca
    24181 ttagctaatt ctacgagccc aactttacct ttagtacttg cacctgtaaa agcacctgaa
    24241 gtatatccaa aaagttcaga ttcaagaagt tgtggagata tagttgcaca atttattgtt
    24301 ataaatgggc cattagatct attgctgttg tggtgtatat atctagcaag tgagcttttt
    24361 cctgttccag attcacccaa taaaagtaca cttacatccg ttttagaaac atgatttact
    24421 gtgtttatga ttggtctcat aactattccg tccataatta cagtatcctc aattctaagt
    24481 gcagttctgt atagtgtttc tacttcagat ttatattttt ttacttgctt ttttgtgtct
    24541 tcaagtttat tttttatatt attaagttca gttatatctc tacaattttc aacagtaaat
    24601 tctaagtttc cattttcatc aaatataggg gtagcagtta tgataagctt tttccctgtt
    24661 tgagtatctt gttccagtga aaatttagtc tttgttttta atacaattgg tatggggctt
    24721 tttgttgaat atccagagtc ttctaaaaaa gaaacatttt ttcctaaaat atcttctttt
    24781 tttagaccat aattttcttc aaatgcttta ttacaatata ttattattcc tttatcatca
    24841 gaaacacata tttcatcatg ggaagcttct aatatttttt gataaaattc caaatctaaa
    24901 ttcattttta tattttcctc ctaaattttt aatgatatat taaaataggt ttaattgatt
    24961 aatatactta aaatttgata tttatatata agtttcagtc tattttaact ttaaataagt
    25021 tatatataac tcattttaca attaaaataa gtctaaatca acttaaagta agtgaaaaat
    25081 aaatataaaa aaattgaaaa tttattagta ttattggaaa gactagggtt ttagagtcga
    25141 tatatattga tttaagatgg catagttttt gcttaaaaag aagagtgtaa attgactaaa
    25201 taaaaataga agggaattta aaatgggaga aaaaagtaaa gggtatgtat ttatagcaat
    25261 agcagggtta ttatgggcta cacttggatt atttggaaag tttttaatgg gaaatggact
    25321 gacatcagaa caagtagcat ttacaagatt gttttttgga tttatagttt taggcgtata
    25381 ttcatctata aggacaccac aaatcttaaa gataagcaaa aaaggaatta tatattcagt
    25441 aataataggt attatatgtc aggcaatgtt taatttatgt tattttaaag caattgacat
    25501 tgcgggtgta tcaattgcag cagttttact atatacatca ccactgtttt tagcaatatt
    25561 ttcaaaaata tgttataaag aaaatattac tagaagcaaa ttattttcac ttattctttg
    25621 ttttattggt gcaattatgg cagtgactgg tggacgtttg gattttcaag gtttaaacgc
    25681 ttttggactt ttacttgggg tattatcagc aatagcatat gcacttatgc caactattag
    25741 taaaaatgct ttaaaggaat tttcaagttc aacaatatta gtatacagtt tcttatttgg
    25801 agctatattt atgattcctt cttcaagacc ttgggaaatc ttaaattatg ctaaggattt
    25861 agatgtttta tcttgtatgc taatgttagg cattgttcca gctgcacttg catatatttt
    25921 ttatgcagca ggtatatcta aaggtgtaga gttgtcagtt gcaggtgttg tggcatcagt
    25981 agaattagtt ggttcagtaa taattggttg cactatatta ggagaaagtt tttccttagg
    26041 gaagttattt ggagtgatgt tgatgttaat atctgcagta gtagcactta atctttctta
    26101 tgatgaaata agaatatttt ataagtccaa caagttaaag cagattgaaa aaactgaaag
    26161 tatttagaat tatatactta aaaaggattt attggtatac attttagagt ccaacaaaaa
    26221 ttataccaaa ttatatttgg tattaaaaaa taactattta taaattttat agaataaagt
    26281 ggacagtaca aataaaatat aagtagatac agtttagact atctattttt tattatatat
    26341 tgtataaatg tacaaattaa tattttgttt tgtaaatact aaataactat agaaaggact
    26401 atatttatat aaccatttct atagttatta ttttgtatta aacaaactta cagccctgat
    26461 aagaatttct agcctttaaa gtatcatcaa tttgatttaa aatttcccat ttttttaggc
    26521 tccatatagg acctactagt tcatccctct taccatcacc agtgagtcta tggattatca
    26581 tagtttcagg aagtatttct aattggtcac agacaagatt gatatattca tcttgttcca
    26641 taagagttaa cataccattt tgtaacatct tttccatagg agtatctttt ataacatgca
    26701 atagatggat ttttataccg tctacaccca ttttaccaac tgcctttgct gtttccacca
    26761 tcatattata atcttcacca ggaagaccat ttataatgtg tacgacaacc tttatatttt
    26821 tagactttag tttttcaaca ccttcaacaa atgttttata atcatgacct ctatttataa
    26881 ttttagatgt agaatcatga attgtttgaa gtccaagttc aacccataaa ttggttcttt
    26941 tatttagttc agataagtat tctacaacat catctggcaa acagtcaggt cttgtggata
    27001 ttgaaagacc tatgacatct tcaagttcta atatagtctc atatttttct tttaaaactt
    27061 caagaggagc atacgtattt gtataggctt gaaagtagcc aatatacttt gcatgaggcc
    27121 atttttttaa catcatttct tttatattat aaaattgact gataagatta tctttagggt
    27181 ttccagcaaa atcacctgag ccttctttgc tacaataggt acatccgcca taaccaagac
    27241 ttccatcaat gtttgggcaa gtaaatcctg catttataga taccttaaaa actttttctc
    27301 caaaagtatt tctaagatag taattccaag tatgatatct tttattatca aaagcatatt
    27361 taaatttatc caaaaaatca cctatttcta ataaaattgt acgctgagct tgtacaaaaa
    27421 acatattacc acaaatagat aacttaaaca aattctattt taagtaatat aaaaatacag
    27481 cgagaaaata attaatattt tctcgctgta tttccagaga aaaatagaac tagtccaaat
    27541 aatattatga aaaaagacat tatcgatact ataaatctag ataaaaaaag tggagataat
    27601 ataaggcata taccaaatag aatcttaact atattccaag ttgtaaattt agaataagga
    27661 ttattcttac tatttacaag tgctactagt tgattaaaga ttaaataaaa tcctaaaaat
    27721 aatgaaaata tgctttgtat tttttgagga aatacaaaaa gtaatataca tgcaattatt
    27781 agaacccatt ggatattaat agagggttta atttcttctt tagtagcata tctttttaac
    27841 tcattaatat tttttaaatt taaatatgca aagaataaaa gtgcaatacc aaaagtccaa
    27901 gaaattaatt ttatacctaa tgtcttaaat gtaaggcata ataatcctaa tataatgagt
    27961 aatactccca ttaacataaa tttaatagca ttttcttttt tattaaagtt attaaaatcg
    28021 atattaaaat ttgtgtacat aaaatcacct ccaaaatcga tagaacaatt ataacagaaa
    28081 ttcatatcca aataaagcct agtgtataaa aattaaacta tacttagtaa ttaattaata
    28141 ggttgtatca taaacttcta ttaatagaat tatatagaag gaggtttgtc catgacaaaa
    28201 ttatgggcaa taatatttgc attattagca ggtggttcta cagctcttga agcttttata
    28261 aatggagagc taggaaaaag tacaacagca ttagtggcca cctttataag cttaactgta
    28321 ggagcaatat tttttttggc aagtataata gttacaggtg acttaaagtg tctagtatct
    28381 ataaatggtt ttaattataa gttgttatta ggaggagtat ttggaggtct aataatatat
    28441 tttacagtaa aggcaattcc aaatttagga gtatcaaata cacttatatt aactcttgta
    28501 tcccaagttt tagttggatt ttttattgat agcgtaattt tgggacaaga aacaatgcat
    28561 ttatacaaat acataggggt tatactttta atattaggga cattctttat agtgaattaa
    28621 caatttaata taatttgcta tgcaactcaa aaatttggta taattatgtt aataaaacaa
    28681 agttagatga aagaggtgtt aaaattggct gatgaaaaat ttgtaatgtc atttagtggt
    28741 ggtaaggata gtatattagc attaaatcga atgttgaaaa aaggatataa gcctgtggca
    28801 ctcttgacaa ctataagtga agaacatgga aagtcatgga cacataattt agaatataat
    28861 atgcttaagc aagtaagtag caacatagga ttacctttat tagttgctga gtgtggcgta
    28921 gaaggatatg aagagagctt tgagagggct ttaataaaag ctaaaaacat gggagcaacg
    28981 atatgtgcat atggagatat agatatagaa agtcatagaa aatgggatac tgatagatgt
    29041 gaagcagttg gtatgaaagt agatttacca ttatggcaag agagtagaga ggatttagta
    29101 tatgaattta tagacagtgg attttgtagt gttgtaacaa aagtaaactt aaagcactta
    29161 ggagaggaat ttttaggaaa aaaattaact agagaacttg tggagaatat aaaaaatgct
    29221 ggtgcagacc catgtggaga acatggagag tatcatacat ttgtcgtaga tggtccaata
    29281 tttaaaaaac ctgtagaata tgaagtaaaa ggaactttaa taaaagatgg ctatggatat
    29341 ttagaaataa aataattaca taaataaaat acctattata taatcctaat ttttgcaaag
    29401 gtctaatatt tgtaagattg tataataggt attttttatt tagatatttt catatattgt
    29461 cactcttatc atctaagcaa ccttatttag attagagtct aatgtagaaa aattcttttt
    29521 tagaaaagct aatgataaaa taagacatat aaactcagaa acaatagtag tcatccatat
    29581 tccttgtcca ccaaatatta gtatcattga aattagactt aaaacaacta ttacaagccc
    29641 tctaccaaga gatataacag tagaaattga tggtttttct actgatacaa agaatccaga
    29701 aattattaca ttaattccta ccaataagaa agatatagag aatattttaa atacacgaac
    29761 tccttcattg aatagcattg tttcttctgg atgtataaat aaagagacta ttggtcctga
    29821 aaaagccata caaattacaa atacagcaac tgatgctatt attgtggctt ttatccccat
    29881 ttttaataat ttttttacat tatctatatt tcctgcacca taataaaagc tagtaagtgg
    29941 ttgcatacct tgagttatac ccatcatagt cataagtact aatgtattta tataatttat
    30001 gacactataa taaataagag cattttctcc aatatattta gtaagactta agttaaaaag
    30061 taaaacaact ataccacaac ttaattcagt agttgaatca ggaaaaccta taaatacaat
    30121 ttttctaagt gtcttaaaat caattctaaa ttttgaaaaa ttcaaagtag agttttttct
    30181 taaaaaatgt attaagaaga aaatagtaga aaagacttga gacaaaccag ttgcaatacc
    30241 agcacctttt acaccccatc caaattcaat tacaaacaag taatcaagta tgatgtttgt
    30301 aagagcagat attattacac caacagtagc taatattgga aagccatcag tttttattat
    30361 aacttctaaa gaataagaca ctataaagaa tccgttaaaa aatattatta ttcctaaata
    30421 atctttaacc ataccaattg tagattctgt agctcctaaa aatagtgcta atctatctaa
    30481 attaaaaaaa gttatagcta atataattat tgataatata attattgata ctaagttaaa
    30541 tgaaaagact tcgttagcag atttaatatc ttttttcccc agatagattg caattatggt
    30601 agatgcacca gttgaaaata atagagaaac tgcaaatata aaattaataa aaggcattga
    30661 tatattgaca gcagctaaag ctaattctcc aactccttta cttacaaata ttccatcaac
    30721 cattgtatat agtgagaaaa cccacattgc aactacagat ggtgctaggt atttaaaaaa
    30781 tcttttacct agactcatgt tttcgtttat agatattttt gtatccattt attatcactc
    30841 cctgtaaatc tattataaaa ttacgaaact attaattaat aattttattt ctaatataaa
    30901 tgataaacta tggtataata ccaatgtcaa caacaaatag tatataatta taaattttat
    30961 taaataatag tgattttaag ggtcttataa atatatctta tttatatatt actgacattt
    31021 aactgacaaa taggaaaaag gtactttaag tgacatttaa ctgacaaatg gaaaaaaagc
    31081 actttgagtg acatttaatt gacataaaac tgaacattat ttgaatagta ttttgcttat
    31141 attttcagat gtttctttat ccatttcatc taataagtga gaatatcgaa tatttattca
    31201 tagctatttt tatatctgca tgtactaata ttttataaat agcttttatg ttagtacctg
    31261 aaagtaatat caaagttgca tttgcatgta ttaattcatg tacttttata tctctaggat
    31321 tattatctct taatagtttt ttaaaatgaa caacaaaagt tggttgaact cacgggttga
    31381 atcttttatc taagcatatc aaatcaaatt catttttcaa tataccctgt aatttcaact
    31441 tattttgttt taatttttcc cctttaagca aacttataag ttcatcagga acaaataatc
    31501 ttcttttgaa tctaggggtt ttagggcctt tgaagattat tttattgtat acataaacta
    31561 atgtttgatt tacatgtgag attttttatc aaggtctaca tctgaccata taagtgatac
    31621 agcttcacca aaacgtaatc caagagttag catcaaaaaa attggtatac ctataggagt
    31681 attttttgat ttttctaata ataattgagc tttttgtttt gtataaagct tagaagttaa
    31741 actatttttt tgattggggt tgtaacaaaa tcacaaatat tttctgatat ttcttttaat
    31801 ctataagatt ctttcaatac taattttata aaatcgactt ggttttttgt tgaatttaac
    31861 atgtgctcat tgtatatgtt atttatataa gactgtaaaa tagaaggtgt tatatctatt
    31921 aatttcatat ctttaaagaa aacttcaatt tgatttttaa tcatattttt tctatttcta
    31981 atagtattag gagaaaaact acattctcta tcttttatat atctgtaaca tctttctaca
    32041 agtgttacat tatttggagc aacaaactta ttattgttta tagtgggcta ttggaaaatc
    32101 gaataataat aacttggtat tcgaaacttt tgataaagca atagaactat atccaaatgc
    32161 aaaacctatt tttcatagtg atataggatt tagattagat gatgaaagtt ttgaagagta
    32221 tttaggaaga gtatttagaa agagatgcaa agggatataa gattgtaaat aaaaatggat
    32281 tttttagtga atttgatttt tataaagcag taaatatatg tttaaatatc tcagtagaag
    32341 atgcgataaa atcatataat atattagtta aatcattagt aatgttagat aaaagattag
    32401 gtaaaaggcg attaaaaaat atatatgaag atatagaaaa agagaataat ttagtaaaga
    32461 aattttataa tataagagtt gaatcagaaa atatgatttt aaagaaaaat gcataaaaaa
    32521 tacaactaat acagaaataa ataaagtaaa gttccatgga aaactgagaa atttaaaaag
    32581 agtgtatata ttgaaatgta gtaatttcaa tatatacact cttttttatt ttgaactaat
    32641 tcctaaacgt caatttagag agtaattgaa ttttaagttt agttaaaatg aaagttattt
    32701 ttactaaata ttatctttgt tgtatagttt tatttataat ataaaaaaag taactctatg
    32761 ctaggattta tgactagaat tagaataaaa gttctagctt ataatatttc attttttata
    32821 agtaaagtta tgagcaaaga tgaatctata gcaaaaatta aagagttaat atttggatga
    32881 cttatccata aactaaccct taggggtgat ttgttttact aaaatcaatt tactttatat
    32941 gggaattaaa ctttaactag cacaatagac taaataatca tgaagtattc gattcgaaat
    33001 acgttgacta tattagattt ttctaaattt tctacaaata tatattaaaa atatttctaa
    33061 taatatattc gagaacataa tacaattggc aaatattata tatgaactct cactttcaaa
    33121 tagctgatat tgccaattag accttaataa ttcatcaata tactcaacga ataatctgga
    33181 taatacaaaa gaaataatta cagcaaatat acctataatt accattttaa tactaatctt
    33241 tatttttttt tgattcattt attctccacc atctctcttt actttgtttc tacaatataa
    33301 caattatgac cttatgattt tataatattt tatttataat tttgtcattt ttgtattttc
    33361 tttacttgtt catatcatta ttatatacaa ttttcgcaca gatttaaaag tattataatc
    33421 cacttgtagc taagaaaaga actctaaata attagtgttc ttttcttatc aacttacgaa
    33481 ccagttggca acatgaaata tttcaacgac acgtcgctta agcgaagtaa attttttatt
    33541 tattatcgtt acatagcatt tgtaattagt tttataattt agttaaaaac tttgagatgt
    33601 gtctttagat tatctaaagt attttttaat attttagatg tatcaatttt atttttctct
    33661 aaaaagtgta ctaatctgta ttttctttgc ttttctaagt gcattaaatg aagaaatata
    33721 tattataaaa tatatatttc ttaatggtgt tagatataca tatattatac aagagttggt
    33781 cgttgccttg acaatgctcc tatggaagga ttttggggaa ttttaaaggt agaaatgtac
    33841 tatttaagga aatttgatac atatgaataa ttagttaaag caatagatga ttatatatac
    33901 tactataata attttagata tcaaaataga ttaaattcta tgtctccatt tgaatttagg
    33961 aaatatttaa gtacagagag agcataattt attttaagta tctctaaaaa aattaaatat
    34021 ctagggtttt atttgacgtg ctctttttta gatagtaaac tttaaaatat agatattaat
    34081 tatatgaata taataaaaag agtactaatg agttacacta gtactttata actattttta
    34141 catgttttaa ctgtataaaa cagcgggtat agttcacaca ggcaggagtg actttagttt
    34201 tgaactaaaa atcaagttca aaaagaataa acattagtat ttgaacttca ctctacgtct
    34261 aaatagattg tagttcttct tgcttttatt ataccacaaa ttggtataga tattcaaaaa
    34321 taatatattt atgatataat aaaaatgtaa atagttttgc agtgagcgat atttgttaca
    34381 aagtagagct taacgcttga aatataaggt gttgagggta tatgataagc tttatcattt
    34441 gcactactca tggttcactg caaatttaag agagttgcat atgtgtaagt attgaaaatg
    34501 cccagtttat tttggggttt tatattaact aagtggtatg taaattgaaa atctagttaa
    34561 aaactgcatc aaagtattga tgttttatat taactaagtg gtatgtaaat cagcaagagt
    34621 cgcaacaaca ttaacaactt cgggagcgtt ttatattaac taagtggtat gtaaatttgt
    34681 attattactt tttatcagaa taatcaaaag atagttttat attaactaag tggtatgtaa
    34741 atgcagaaga aacaggtttc aaaacgataa aaaaataatg ttttatatta actaagtggt
    34801 atgtaaatag agagaagggc tattctctct aggcttatcc ttacaagttt tatattaact
    34861 aagtggtatg taaataaacc aatctttttt ccttgaatct tttaaaagtt ccgttttata
    34921 ttaactaagt ggtatgtaaa tgattttaga acttcatcca caaacgagct ttctacagtt
    34981 ttatattaac taagtggtat gtaaatatag tccttttcta aatttagaat caagttttgg
    35041 agtgttttat attaactaag tggtatgtaa atagagtaaa acaatagtac aagaacaaat
    35101 aaatacatgt tttatattaa ctaagtggta tgtaaatact ttttcacgac atttttttat
    35161 aaaaggaggt attagtttta tattaactaa gtggtatgta aataaaatta tagacagaat
    35221 gataaatgta tttgatgctt gttttatatt aactaagtgg tatgtaaatt aactttataa
    35281 aacccagtaa ttgcaacact tttatagttt tatattaact aagtggtatg taaatagtat
    35341 aatgttgaaa agttagagag tacaatcaag gaattttaca ttaactaaaa tgtatagaat
    35401 aaaacatgta tttatactta aattctgtac ctatataaaa aagtgaactc tgtcaacaaa
    35461 gcactttttt atatagataa attatcattt tgttttaaga tagaagatac taatgctaaa
    35521 tgtttatcat tagtatctgt atgtacataa aagtttaatt ttttatataa atttgctctt
    35581 tagaaaaatg agcagtatca ataaatatat tgtctaaatt ttttctagga actagttgac
    35641 tagctataag attagcttca attctttgat tgttagacta tgaaattaaa tttaaaggtt
    35701 cattcttggt cgtataaata gctttattat tcgtatgtac tataacaatt tttgccatct
    35761 gcttttgata gataaagagc tttatcagct ttagaaaata aatctttata taatttagtt
    35821 gaatcatcag tgaaggcaat accaatactt aatgttattt tatgattgtc ctttactttt
    35881 attttacttg catcatttaa aatatcatta gtaattttta ttattaaatc ctttgttaat
    35941 gattttataa atattgtaaa ttcatctcca ccaattcgag caactatgtc tttatcatgt
    36001 gtgttatgta atagtatttt tgatacagca actaaaactt catttccctc taaatgccca
    36061 aaagtatcat ttacagtttt aaaatcatca atatcaataa ctaatagagc atcattattt
    36121 ttggaatcag aactacatag atactcttca ataagatttt gtgatactct ttgattatat
    36181 aattgtgtta gtgggtcacg ttgagcctga ttaattaagc tttctaattt agatttatct
    36241 tcagttatgt cttttaaaac gcctattgtt ttgatagggt tatggtcact atcatatata
    36301 actgaacatt gaacacgaat ccatctccat tcatttttag ttaatgaatt tacttgtctt
    36361 atctcaattg tttcacgaag atttccatga agtacttcta gtagttttcc aatatcatca
    36421 aggtgaataa ttttaccaga ttctaatagt ttggagtaat tttttgtttc aaaattttct
    36481 aattcaattt ttttgtcaat ttctacacgt tgatatttta taagggtatc gttttcaata
    36541 tcatactcaa acatgatatc tgtaatattt tgcaaagcaa tacgatatcg ctctctttct
    36601 aattttagtt cagattctat gttttttagt tgggttatgt cagtaataat actattaatt
    36661 tttactatgc catcactatt taacgatttc attccagaat ctaataccca cattaatgtt
    36721 ccatcttttt ttcggattct atattcagat gaatatgtag gtccttttgc aaaacatcgt
    36781 tcacaatctt ctagtgcttt aggtaagtct ggtggatata cagcacccac tgctgaacca
    36841 ccactcattt ccatgaactc atcatatgtg tatcctaata ttttgggcaa tccctcattg
    36901 acatagaaaa atgagtatgt actatcatca ttgctacctt ttaagccacc attgatatta
    36961 tttgtaatca tttcaataac ttctgttttt tcttttagta atctttgcaa ataatcataa
    37021 ctttgagttc caattttagt gggaaagtat tcatcaagtt gcatttcacc ataagggttt
    37081 gatatgtgca tgtgctttat taataatttt cctctatcct caattatctc aaatgtacaa
    37141 cgttgattta cctctaaaat catttgagca ttttctttag ttcgaacagt atatcttcct
    37201 aataccatac atctattctc atcttcactt acagtttcaa atatatcatt atttatatca
    37261 caagaaggaa tttcatcttg acctgcataa aaataatttt ttatttcatt aaaagaagtg
    37321 agaaattcct gttctcctgg tccaatccat gtaacatttt cacaaaggta ttttaatact
    37381 tcatcaatat cccgatttat ataaaaactt gttataatat gttttgctaa tttgggtgct
    37441 ttttttagga gtatgctcat gatattcctc ctttcttttt gctattatat tttaattata
    37501 ttatacatca atatatttaa attaaaagct ttgttaaact atgatatctt tgtcaaataa
    37561 gttaatttta acaaaaaaga actgaaacaa tatatgcttc agtacttaat gtcaatatct
    37621 tgtatagata catatttata aactaatgta caagtttaaa aaaagaaaga taattttaat
    37681 ttattttaaa ataacaatat taataatcat ttttatcaaa ttttttcttg tttttctcct
    37741 tgtttttata cattttttta tccaattcaa ctattgtcaa ttttaaattt ctttttactg
    37801 tatcaacacc ataactaaat gaaagatact tatacttaga gaatactttt aaaaaatttt
    37861 ctcttaaggc ttctagctgt gaataaacat aatttttgtc aacatcacta gagaatataa
    37921 caataaattc atctcctcct aatcttataa tagaagtaga atttattaat tctttattta
    37981 aaagtgaaac aaaatcacat aaaatcttgt ctcctacatt atgaccttca tagtcattta
    38041 tcattttgaa attatctaag tcaattagta caatataatc tcctataaat atgtcaaatc
    38101 tatcatttaa atattttcta ttatatgctc cagttaatgg gtcagtaatt gagtagtgaa
    38161 gatttctctt attttcttca tagagttttg ttatatcatt ggccatagta attatgtagg
    38221 ttttttcatc aacatctact ttatattcta aaacattcca atagcttgta gtatcttttt
    38281 taaactctaa aatccaattt gaaattttat cataaggata atttttttcc caatctaatt
    38341 gaatattgtg agaatccgta aaaaatttag caatattatc agggagtttc ttagctattt
    38401 ctatattagt cattccaagt ggattatctt gcatataact tttaattaaa ttttttaaat
    38461 tatcatttat aaatataatt ctgtagttag aatctcttat aattagaaat cctggaaaag
    38521 ttcttaaaaa aatttcttta aacatattaa tttctccaaa ataaaatact ttgtactaga
    38581 tttttgttaa attttttatt ttatttacat ctacatacat accctgggca atcgaccttc
    38641 catcaattgc agaaaggtta cattgtgtat acataactgt gacaatttga ccatctcgtt
    38701 ttatgaatct atataaaaat ggttcaattt tatttgtgtc aatcatatcc aaactttttt
    38761 tataaacaaa gtctaaatca tctggatgaa caattgctct taaatttccg cccatctcac
    38821 caaaaaactg ttcttttgta taacctataa tatcaaacat ttcttcattc atataagtaa
    38881 taatcatatc accaaataaa tcgtagcgaa ttatacctac aggcaacatt gaataaaatt
    38941 gtgataaaat attactttca tcaagatgtg tatttgtcat tttaggtatt gaatatgatt
    39001 caaattcatt tatatagcca gcagttttaa ttaaatccaa atgtaatttt gctaagagta
    39061 atttattttc tgaaattata caatttgcac taaagtagaa attgctatat ttttgatgtt
    39121 cagaagcttc atctgataaa acggcttctc cactaattaa taatgaatct gattcagtat
    39181 tatgtggggt tatacttttg taaagaatag aaaatttttt acctttaata tgtttttcaa
    39241 aatgttctat tactttagga aaagatgtaa tttcagtttt gttgtaaaaa tcaaaccatt
    39301 gaatgtcttc agtgacatta gctcttagtt ttttcatatc ttgcataata aaaaatccat
    39361 caaatatctt ctctattaaa gattttccta tatcagaata ttttataaac attttctttg
    39421 aattattctc tttagatagt aatttttcaa attctttgca ctccatgggt tttgcataat
    39481 aataaccttg ggcgatatcg caatttatac ttttaataaa ttctacatgt tgttctgttt
    39541 caacaccttc acatactgta agcatcccaa gagctcttgc aatgtttatt atagagtaca
    39601 aaatggttgt atttttaaaa tcatttaaat tatgagataa aaatatccta tcaattttga
    39661 ttatatcaaa aggtagattt tgcaacatac caaaagatga atatccagaa ccaaaatcgt
    39721 ccattgatac agaaaaacca taagaacgaa gttcagctag ttgttgaata attgtatttg
    39781 tattttctat taatatattt tctgttattt caatgctaaa atttgatgta gagacgctgt
    39841 acttttcagt aatacctttt agcatacttg gaaaattagg gttaaaaaaa tgaagacgag
    39901 aaaagttaca acaaattgga acaaaaacat cattgttatc aatccatctt cttatatttt
    39961 tacagttctc ttcaaataaa tgcaaatcta attccgttat cagaccaaac tgttcaaata
    40021 aaggaataaa tttatctgga gtaagaagtc ctttaatagg gtgtctccat cttgcaagtg
    40081 cctcacatcc aactatagta ttatttttta tattataaag tggttggtaa aatacttcaa
    40141 tttgtttagt ttgtagaaca tgtgatattt ctgataagaa ctccttatca ttttctaatt
    40201 tattgtaaaa actattatct ttaaaatcaa atagaatgta tctatttttg ccttcacttt
    40261 tagccttttt taaagcacta tatacttggt tgaaaagcat caaagtagtc atgtttggtt
    40321 caccattcca gatagtgctg ccgatactaa atgtaacatt ggagtatatt tctttttcat
    40381 taggaagttt tatttttaat tctcgggcgc tctctataat agttgcaccc atattattta
    40441 actctttatt tgatacattt ggaagtacaa ttaaaaaacc ttctcctttt aaataagcga
    40501 ctattccctt tgattctgga ataaagtgca ataggttttg agttagagta attaataaat
    40561 tttctccgac tagatatcca tatatatcat taaataattt aaagttatcg atatttaata
    40621 acatgattcc tatatgtata tttttcgaaa tacagtcatc aatatgttgg tacataaatt
    40681 ctctgtttgg tattttagaa aaaaaatcta tttcatttaa ggtttttaat ttaaaatttc
    40741 tactatctaa ttccttagat aatacttcta cctttttatt taacattttt atataattat
    40801 gattttgcat ggtattcctc cataagatac tttaaatttt gatgacaact gtatttatgc
    40861 tagaagtatt taaatgttaa tttgtaaata atttaaatgc taaattttaa ataagtattt
    40921 aaaatgaata tacattaagt tacttgctcc aatgctacaa atacaaatat tttttagttt
    40981 agtaataata ttagataaaa ttagttaatg cttaaattct agtatattga aagatttcct
    41041 ttttgaatgc aattatatca tattttttca taaatagata gattgtgagc tgtatagtta
    41101 gtaaggtaga gtttttttat aattaatttt aagtttaatg atttttcaaa ggcataatta
    41161 ttttattcat aattaacttt ttatacataa tttaatacca tattaataat tttgcataat
    41221 taattttagt tattaaaatt aagtttattc ttgtattttt tgttaaagac tataataaat
    41281 attcatttac taaatttata aactattaat ctatagaaat cagttttaat atgaaaaata
    41341 ttacatagag atggatataa tagctgtaaa cataaaacta tataaaacta aaatatattt
    41401 ataaaaaagt tgaagttata aatactatac ctaatattac aatataaaaa tattttaata
    41461 attaattatt aggatgttta ttttcctatc cttgttttaa ggattttttt agtatattct
    41521 aatactatag tattatagag taataatgtt gatttaaaat aaaaataaga tttcggagga
    41581 gtttattata taaatgaaag attactataa aataggagag atatctaaaa tatatggaat
    41641 aggtagagat tcattaatgt attatgaaga aataggcatt ctaagaccag ttagagatat
    41701 aaatggatat agaatgtata atatatcaga tatatggaaa ttaaatttaa taaaagaatt
    41761 tagaagcttg aactttccaa tgaagaaaat aaaagaatac ctagatgaca gaagtataga
    41821 gtctacgaaa aatattttaa atgaagaact cgatttaatt gataaaaaaa tagctgaatt
    41881 tataagccat aaggaaaata ttataaaaag attgagttca attgaaagtg taattcaaaa
    41941 tacaaaaata gatgagatag aggttgtata tatagaaaaa agaaaagctt tagaattaaa
    42001 tgctgatata aagagggatg aagacttcga ttttttaatt caaaaacttc agaaagaata
    42061 tgaagataga tttaatatac ttggaaataa caatattggt tctgcctttt ctactgaagc
    42121 aattaataaa ggtatattta atgagtttaa atctgtattt tgttttctgg aaagtaatga
    42181 gaaagtatat aatatagttt ttgatgaagg atattatgta actttaaatt atactgggag
    42241 taattctaat aataagatgt atatggagaa ggtgtttaaa tttatagaag aaaacaatta
    42301 taagataatt gctgacccta tagaaatcta caagatagat atacatgaga ctggaattgt
    42361 agaggagttt gtaacggaaa ttcaagttcc tataactaaa tagctatatt tcaatggatt
    42421 agatggtaaa tagaatgaaa aaatgttgat ttgccaccga tttgtcactg tgttataaaa
    42481 tcggtagcaa attatatttt aaattataag atagcatgaa aaaataattg tttagggggt
    42541 tataaatgtg aaatgttcta attgtggaag tgtaaatatt gaaaagggaa ttttaacaac
    42601 tggtggcata tatgctgaaa ctattggatt aaaatataga ggagatggaa aattagataa
    42661 agttataaat aaaacttttc cagtacaatc tactatatat tcagatttat gtttagattg
    42721 tggagaaata gttagaacct atataaagga taatactgat aggaattggt gtaaagataa
    42781 gaaatagaat aatttttgaa gtatattaat atttgaagtt gaattttatt aaagatacaa
    42841 gtgaaaaagt ataaatggga agaaattgtt gtatggaaga aactttgcat ataggggaga
    42901 ttagtttttt aatataataa catttttaaa tgtagataaa actaaaaagg gttctctaga
    42961 aaacaatttc tatttaatta tacttactta ccaataccat cacttgatgt aaacaagatt
    43021 ctactacatt ttctccgtac tctagtataa aatcatctag ctgtgtatct ataaaatcac
    43081 aataatcata taaactacta atataagcag ttaacatgtg tgtacattta tccatttcat
    43141 ctctaaacat atatattact atccccctaa aaaactttca taaaacaaaa agaacaatat
    43201 ctttttggca actggctgac ataactcata gtttatttta taagcgttag tccctatagc
    43261 tttgcgtcac taaatttctc tagttttgcc gatttagttt tattctacaa ctaaaataat
    43321 acactaggat aagttattgt tcaacatact tgtcagaaaa ttgaaatatt taacaatatc
    43381 ttaacaatat gaaatctatt tttcactcaa gaaacaaact atatgtatag aatgtttaat
    43441 aaaaattata tttagttttg tattgaagtt tttatattaa aaagtttagt tcacaagggt
    43501 tacttggcta gataatagat gaacaaaaat atcttgaaaa aatatatatg aatggcaaaa
    43561 aacaagggat gaattttata tagactcatc ccgtaattat ttatatattg accttgatta
    43621 aatatattat tatttttaag cttcaatttt tatattatat ttctaaagtt tctataagag
    43681 gattatcgct aaataatttt aataaatttg tttttttata tcctttaggt aacttagtat
    43741 atataactac ttctaaccaa tccccatcaa ggcgtttaat attcatgttt ataatttcaa
    43801 tattagattt tttaaattta ccttcaatat attctatgga atcagtgctg ttagaaattt
    43861 taagagaaac ttgctctgct gtagggagtt tcatccattt cctatctcta tgaagtgtta
    43921 tctgtacaat aacaataatg atacttgaaa caataccaac taagtataat ccagagccaa
    43981 tggcaagacc tgtaccggct gttgcccata taccagcagc tgtagtaaga ccacttactg
    44041 attgatttct aataaatatt aatccagcac ctaaaaaacc tataccactg acaacttgtg
    44101 ctgcaacgcg ggctgggtct agaccaatac ctggagtacc cactatatca ttaaatccat
    44161 acttggaaac aatgattata agtgctgaag ctaatgccac tataaaatga gtgcgtattc
    44221 cagcttcttt tagtctattc tttctctcat atccaattaa agccccacag aaaccagcag
    44281 taatgattct tgctatatat tcaaattgaa tcaatatatg atggttcatt tatctagcac
    44341 ccccttctat ataatattat atatactata atactacatt ttttatgtga atatagtaaa
    44401 gtttaaaatt tatataatag ttatatatga atataaaatg tataaacgta tattatgtat
    44461 ataaaaatga tagaaagcat ctaattttaa atgattaaag agcaagctta aataaatcaa
    44521 acttgctctt ttaacatagt gtatgttttt atttgtgata gttagataaa aatttatctg
    44581 tgttttttac atctgcaaaa ctgttctgta gtgatgccat gaatacttga tgtacagtat
    44641 ttgcattaat ttctatatta ttccaagata aattcttcgt tgtacatgca tcgcttatta
    44701 gagttatgtc gtatcgaagt ttctttgctg ttcttacact tgtatcaata cacatatggc
    44761 tcatcattcc acagattact agattagtaa tatttttttt atcaaggata ctttgcaaat
    44821 ctgtttcaaa gaaactatct ggtgtgtgtt taattataat ttcttcatta tctagtggaa
    44881 aaacaatttt atttatttct gaaccatgag tattaggaag aaaaaaagaa gctgttttat
    44941 ctgttgatat atgctgtata tgaataactg gtaaattgtt ttttctaaaa aacagtagta
    45001 tttttttagc attttcagca gtttcttctg attgaaataa ttcacatttt ccatttttaa
    45061 aataatcatt ttgaatatca atcaatatta aagctataga catgattata cctcctattt
    45121 atttttatta taatactatt gtaaaaaatg taaattactt actttttggt atgtatagga
    45181 ttacttattg tagcaaattc ctttattatc tagaatttct tgttgaccat gttcaagcat
    45241 atattcgatt cctatttctt gcattatttc cactgctttt aacatttttt taccacgatt
    45301 agtaagaaaa tattcaacat gtaatggata tccagcagaa cttattttat caataatccc
    45361 aaaatcacgt aactctttta attgttgaat caacattttt tgatttattc cataaatatt
    45421 atgttgcaat tcagaaaatg ttttattaga ttgtcttaat tcaaatataa ggatagtttt
    45481 ccattttcct ttgattatgt catgtacaat ttcaagagga catgtatatt cagctcttat
    45541 tttcatagca tatcaccccc agtaaaatga taataaatta tatcacttgt cttgtgatat
    45601 gacaaatata tatgaactgt atataaattt tatgttttat taagttctaa atttcttcta
    45661 ttgtagttca tatttagtac ataaataatt agtaagatat aagtaaataa atatataaca
    45721 tgactataga aatttaactt taaaataact tatgataatt tagaggagga atatatatga
    45781 atatatcaag aaaagctatg aaaataatag aattagcaca aaaaattgca aataagaggg
    45841 ggatttcagt agaagaagct tggagtgaag cagtaacaga atataaaaat aaatacgaac
    45901 atattgcata gatatttaaa aatttagaat atttggtaga atataatgat tttaaatgat
    45961 actataaatt ataaggtata tcattattaa catagaagga ggatatctgc ttgattgtaa
    46021 aaatagataa tactttagaa aaagaatttt ggcaatatgt atcacatgaa gaaagtctaa
    46081 atttattcat aattggatac gttgagaatt atggatttag ctctcaatat caagatatat
    46141 ggtctcaggt agaagatgga aatataacct ctataatatt aaaaaataag tcaacactta
    46201 taatttatag ttttaaaaat aattttaata taggagaaat gaagaatcat ataaaagatt
    46261 tagatgtaga aagcataagt ggaaaaaaat gtgtaataga tagactaata agtaaataca
    46321 aagattttta tgaaaaacta gataataaat tttgtgtatt aaaagaaata aaagaaatag
    46381 atttttccaa catgaaggag tataaaatag aaaatgctca ggaaaaagat attgatgaaa
    46441 taggaaaact tttaaatagg tcagactata aagtaagtaa aaattacata gaagaaagga
    46501 aagaacattt aaaagaggga aatgtaagag catattttat tagaaatgat gatactatga
    46561 ttagcactgt gtcaactggt atggaaacta gttttttggc aatggtggtc tctgtaagta
    46621 cagataaaag atatagggga aaaggacttg caagttatat ggtttacaat ttgagtaaag
    46681 aattattgtt ggaaggaaaa gttccatgtc ttttttataa taatgatgta gcaggtaaaa
    46741 tatatcataa tataggatac aaagagataa atgaatggac aattcttttt aaatagctat
    46801 aaaaaataaa aaactctatc gagaattaaa gtatttataa ataactatat ttttactata
    46861 attcatgata gagttttttt aaatttatga tactattttt tattatttaa ataatcaagt
    46921 gttttaagtt tataaccttc tttttcccaa tgtgtaagaa cctcatctaa tatctcagta
    46981 tttgttgatg aatttggatg cagtaaaact attgcaccag gatgagttct tgaataaatt
    47041 ttgtttttgg caaattcatg agtaggttgt ttcttttcat accaatctac ataagcaaaa
    47101 ctccaaaata ttgatttata tcctaaatct tgtgtatatt ttaaagattg ttcgctaaat
    47161 ttacccattg gaggtctaaa atacttaggc atttcttttc cagtaacatc tttgtatgct
    47221 ttttctacac ttgtaatttc ttctttgaat ttttcaaaat ctgtaatacc tgccattgat
    47281 ggatggcttt ttgaatgatt acaaactaaa tgtccttctt tttccatacg ctttattaac
    47341 tctggattgc tttttatata actttcaact acgaaaaatt gagctttagc attgtgtttt
    47401 ttaagcgtat ctaataattt tggagtgttt ccactttcat atccagcatc aaatgataga
    47461 tatataactt tttcattggg atttcctaca taataagctc cgtatttttt aaaaaaatca
    47521 gcttctttta taggtgatgg ctgtttacca tcctccctag ggttaaaata ccaatcatat
    47581 tcatgtgtgt cgagtgttgg actagaaatt tgagtttttg ttttatctaa tgatttaaaa
    47641 tttatactag caattccaaa aagtactaga gcaaatgctc ctatcataat gtattttttt
    47701 aggctatctt ttttcacaat ttcacctctt atttaaaatt taaaatatat ttcttataat
    47761 atagtttgaa tatttatagt taaaaatatt cacatataca aataataaat gaaagaagtt
    47821 tactgtaaga tataaagttg atattaatta tcttaaataa agtgtatata aatgataaaa
    47881 tataaagaga aatgattgta aataagttag gctggtttaa cttgaaggga tataaaaatg
    47941 gataatataa taagtgtatt gaatgatgtt gtttttttag atatagaagt tagtggatta
    48001 gattgtttaa attcagaaat tttagaagtt ggagctgtca aggttaaaga ctggaaaata
    48061 catacctatg aatcattaat aaaaaacaaa tttgaggtac ctatagaagt attctcagta
    48121 tgtaaaaatt tagataaaaa tgatttagaa atagctaatg aaatagaact ggtggaagat
    48181 agacttgtaa attttgtaga agatagtttc attatatgtc atgatttaag tctgaaaaaa
    48241 aagttttttg agtatcatat gccaaagtta aaaaacaaat ttattgattt aattgaatta
    48301 gcagttattt tagaaccata tcataaagat tatagcttag aatacttaaa aaatacttta
    48361 acaaattgta attctaaagt ggaaaataga gctttatcag atgctattga tataataaat
    48421 atagtaaatt gccttttagt aaaatttaat aactatgaaa aaactacttt ggagccattg
    48481 agttttaaaa taaattcata tcttaaaaaa tttaatcttc caacatggga atggagcaaa
    48541 tttttagaag aggcaaatta tgatttatca aataatataa atataaaaaa agaatataat
    48601 atatttgact caaaagaaga aaagaagaag gaaagagaaa ccttaaaaat tttaaatgaa
    48661 gaagaaaaaa attatgaaga attattaaaa tacaaaacta tttgggagaa taaagaagga
    48721 tttacatatg aatatagacc tggtcaatat gagcttacta aaacaataag agagttgttt
    48781 agaaatagcg aagatgaaga aaaaattgca tgtatagagg caccaactgg tataggtaaa
    48841 agtgtaggat atttattgcc tgcaatatta gaggctagaa ttaataaaaa aagattatta
    48901 atttctactg acacaaagga attgcagata caattaataa ataaagatat tccaaatgtg
    48961 ttagattctt tgggtctaaa tggaaaagta agttacggat atataaaggg aaaaaataac
    49021 tatatttgta tagatagact ggaagcatat atagatgatt atgagtctca aaaccctact
    49081 aaaggagaaa ttttatcttt aatatttttg aagagattag ttgaaggtgg caagtatgga
    49141 gatatagaag aaataaatta tttagtgttt gacaacttca aggaaataag tactcactta
    49201 agaaatgtaa gttgtgaccc aaatatgtgc agacctaaaa aatgcaaaaa agattgttta
    49261 tataaaaaca gaatagaaga attaaaagaa gaacatataa cagtagtaaa tcattcacta
    49321 ttagctaaat ggccgtataa ggatgaaaaa cctttagaaa atataatagt agatgaagca
    49381 cataatttga ctgaaaaagg atatgatttc ttttcaagca ttataaattc aaagtcttta
    49441 aggtatttat tacaagaaat ttatccttac gagtttattc aaaatagtag ctttatatat
    49501 aaaaaatata gtagaaatat gagaaaaata aaggcttttg ataaatttta taatgtatta
    49561 aaaattggaa gagaagataa acaaaaaatt gctagaagca taaatctcat tattgaagag
    49621 atagattcaa tattaaattt tggtaattgt aatgaatata ataatgtaag taattataat
    49681 ttaagatggg aactgaattt gcaaatagat gaaattgtgg gaaaactaaa aaagggtggt
    49741 atagatactg aaataagtta tagagcctat agtgaaaaga taaagttgag ttgtgagaaa
    49801 ataataaaaa atttagtttc aataataata ataatttata ggaatattga tgatgatagt
    49861 atagataaag aagcagatat atataaattt ggaaaggcaa agacaagaga tttagaggat
    49921 ataaagatta tatttgaaat ctttttagag tatgatgaaa aggatgatta tgcaaggata
    49981 gttgaaattg ataagaatta taatgacttt gaatttcgag tagtgccatt aaaaatagca
    50041 gatttatttg aagaaaatat tttatctcaa ttagaaaaag gaatattttt atcagcaact
    50101 ttgagtttat ctgaaagtat gtcttatttt aaaaatacat taggaataga cagagttaag
    50161 aatgtggaaa agattataga accaattttt gattataaaa atagagtctc tgtagttgga
    50221 ttttctgata tttgtgagta cagaaattct gaatttccaa atgagatgag taaaattata
    50281 tctaatatat caaagattac agaaggtcat acattagctc tttttaatag taaagataga
    50341 caagaaaaaa cttatgaaat attgaaaaaa tacttacata gttttaactt agaaatttat
    50401 gctgataaaa agggcattag acaccttaat gatttaaata gaaaatgtgt agtacttggc
    50461 tcaaaaggat gttttgaagg cgtagacatt ccaggggatg gtttggtttg tgtaacttta
    50521 gacaagcttc cgaatctaaa tccaaaagac cctttgtatt ttactataat gaagaagtat
    50581 ggtatagact actatactat aaattatcct caaatgacca taaaggtaaa gcaagctatg
    50641 gggagaattt taagaagcaa atatgactat ggatgttttg tgatttttga tgtaggaact
    50701 aatataagtg ttttaaagag attagagaaa gatttacacg attgtaaaat ttcaaaggtt
    50761 aatagcaatg agttttatac ttatataagg cgacatttaa ataaatctag aagtttaata
    50821 ctaaaatctg ttatatttga tactataaaa gcgttgaatg ttgatgctaa aatggataac
    50881 aatgatgttg ataaggatat tataaaaaaa gatataaatg aaaatataag acaaagagct
    50941 gtaaaaggag aagtgtacca tattgatatt ataaaaaaag atatgaaagt aaaatatttt
    51001 gatagaaact atcttataaa tttagatata tttatgagag aagaagataa aaattaagag
    51061 tgggagtgat atatttggca aaacaaaagt tttatgctgt gaaaaaaggt aaaaatatag
    51121 gtgtatataa tacatgggat gagtgcaaaa aacaagtaaa tggattctca ggagctgaat
    51181 ataagagttt ttctactttt caagaagcta aagaatatat tgatgggtca gaaaaattga
    51241 gttttcaaga agataaggag tttatagaag catatgtaga tggaagttat gaacattcag
    51301 taaaaatgta tggttcgggt gttgtgattt taaaaaataa tgaagttata aaaacttata
    51361 gtgaaaaagg aaaagagaaa actttagtaa gtatgagaaa tgtagctgga gagatagagg
    51421 cttctaaaat tgcaatgcag tactgtattg acaataatgt tcaaaacttg attttatact
    51481 ttgactatga agggattgaa aagtggtgta ctggagtttg gaaaacaaat aaagaaggaa
    51541 ctatagcata taaaaatttc tatgacagta ttaagaataa gcttaatgta aaatttacaa
    51601 aggttaaagc tcattctgga aataagtata atgaggaagc tgataaatta gctaaaaaag
    51661 ctattggtgt ataataaaaa aatatttata cataattaca tggtataaga gtatatctaa
    51721 attcctactt tataattaaa caacttgtaa ttaaacaact tataattaaa taaattttga
    51781 ttaaaaaagc agattgtatt atgaaaaaat aagtatctaa tttataaaca attaataata
    51841 gtattaatta gatacaactt atttaatata ataaaatctg ctttttatat aactataaaa
    51901 ttttcctaca ttctattaga attgcccata aataccttca agttcttctt ttaatacttc
    51961 agggtcattt ataccaatag acatggttct agccagtata tttgcttggt cataagttga
    52021 tgtccatgag aatacaccac ctagacaatt tctaagaaca tattgagttt ttaagaatat
    52081 tgataaagca tcatcatatg acattgcaaa atctccatcc ttaactaaat atggaacttg
    52141 agcagtatta tcaaatctat attcatatcc atttttattt atataatccc ttctaagctc
    52201 atcataagtt cttgttatag tagcacctaa tcttccataa aatggtatac caagaaggat
    52261 tttttcagaa ggcattccag cattctcaag atttcttacc attgcatcaa cactatatcc
    52321 tggcaaagat aagtctgaat caaaaagatt tgcttgatgt tttctaccat ttgggcctgt
    52381 ttcacctgct gtaaaatcat aactcataag attaaaataa tctattatag gagctatttt
    52441 atctatttca gcacttgaat ttatatatcc tctatctcct gttccagcta cactaagcca
    52501 tttatcatct cctataacat ctcttatggc agttagtaag agtgtaaagt tttctctatc
    52561 ttgaggtctt gatgttattc cagatgcact acttccagga tattcccagt ctatatctat
    52621 tccatctaaa gcatattcat ttatcatctg attgacctgt cttgcaaaat tatatctaga
    52681 tgtaggtgtt aatgctgcat cagagaatcc ttcagctccc caacctccaa tagctacaat
    52741 tacttttaag ctaggttttt cacctttaag agcaagtaat tgatttaaaa atctaggata
    52801 aggaataaac aaatttccag actggtctat ctcagcaaaa gcaaatataa ctgcatctaa
    52861 tagttgagca tctacattag ttggatttcc aagaacatat tctgctacaa ttggatttat
    52921 atctggacag tttgcatttt caactattgg attgtatggg tctgttattt gtggtctaac
    52981 taattttttt gaatctttta aagttttcat agctattttt ttagtatttt tttcgctagt
    53041 ataatcgtag tttttataat tatgtttata gaaatcttca taactactat cttctttatc
    53101 atagctagaa tttattttgt cgcaagattc atctttatca tagttaaaat tcatttcatc
    53161 acaagactta tctttaaact tatcttgttt ggagttgtga actttgttag tatttttagt
    53221 atgttttttc tcatggttgc aatcatcttt aatatcagtc ttgtgttctt gtttacaatc
    53281 aagagctttg ttcaggtagt catgatgttc atgttcacag ttacattcat tttcaatgtt
    53341 tttagtatgt tcttttttcc agctacaagt attatcaatt ttcttgctca cttcttcatc
    53401 attataatta tctggtacaa aacataagta ccagtccata catgaatatt tcttattaca
    53461 actgttaact ctatttttta attccttata gtttttagga taaggtaaaa tcactggcat
    53521 tccaggaaac cagtttgcag gagtaactat attatctcta tcactagtct gaagtgcatc
    53581 tactattcta agtatttctg gaatatttct tcctgtagtt agtggataat aaagaatcgt
    53641 tcttagaatt tgattattat ctataataaa tacagagcga acagttgatg tatcactcat
    53701 tggttttgat atcatgccgt ataacttggc aattctcata tctctatctt ctataatagg
    53761 aaatggaatt tctacacctg taagtaaaga aatattatac atccaagcta aatgtgaact
    53821 gttactatca acacttagac caattagttc tgtatttctt tttttaaatt cgtcataata
    53881 tttagcaaaa cataaaaatt ctgtagtaca aactggtgta aaatcaccag gatgtgaaaa
    53941 taaaacaatc caattaccct tatagtcaga gagtctaata ggaccatttg ttgtattggc
    54001 tttaaaatca ggagcctttg accctaaact tggcaaattt ggcatgtaaa tcacccctca
    54061 ataaattatc atttatttta ttctattaat taatacatat tagtgttact attttattaa
    54121 aagttaagta atccttatgt caaaaaaaga tatttattaa aaagatttaa tattttccta
    54181 atataaatga caatagtaat tgctattttt ttactaattt ggtatagtaa tggataaggg
    54241 gtagtgtcaa ttttagtgat tatacgaggt gagtggattg aaaaaaattc taagaatttt
    54301 agttatctcc atgatgatat gttttgcaat gacttttgca ttagtgttaa taaattcagt
    54361 tatgggagta catataggat tggattatta ctttttgatg ggaagtgtgc ttacagtttg
    54421 tttaacaatt ggaattgttt tatgcaatgc tagaaaaata tttgatagca aagctataca
    54481 caagacaaga acgaaaactg tcagtaataa taaaaaacaa aagagtcatt ctagggatat
    54541 aaaaagaaag atatcataat ttatgtaaag gaaatattta tgtataaaat aatgattgat
    54601 aggtaaaata aaaacacgat ttaacttgtg tttttatttt ttttcaagaa ttatgatata
    54661 ataaccaata agaaatttag tttaccataa aatataaaga ttattaaatg gagagggaac
    54721 tataatgaat tttagagatt tatttgagaa ggctgtagat tttattgatg aaaaaaggaa
    54781 atctatagtt gcgatttcat tatcaacatt aggtgtaatt gctttgataa tagtattttt
    54841 cttaagtagt aacgagttta gtgtaggaaa tgaagctaat gagttgttaa agattataga
    54901 gaaaagacag tattctatag ctgttgatta ctacacaagt atagaaaaaa agttttctga
    54961 ttcaaaaatg gaaaggttta ataagtctgt ttctaaaaaa ataaataaat tgctattaaa
    55021 tagtggtgat aaatatttag atggagacat aagtcaagaa agttttattg gattaataaa
    55081 taccgtgaaa gaattaaaca aaataagtat agatgtggat gacttattag ctcaagctga
    55141 tagagttaga gaaatgtata aagaagaaaa tactacttat gatattgcca ttaactacat
    55201 aagtactgtt tcaatattaa atggtatggg tagtaaccta gatgtataca aacagaatat
    55261 agaaacaatc aaagagtcta gagatgttta tgactcagca gtaaaagacc aaaaagcata
    55321 taagtattat gaagctattg aaaagtataa taaagtatta aaagaagatg aaaagtatta
    55381 cagtatggct caaaatggga aagaacaatg tattgaagaa atgtatgatt actatataag
    55441 tagagctgaa gaggcaaata cttctggaga ttatgaaaga gcattacaat atattgagta
    55501 tttaaaagac gattattcag atgatgaaaa ggtacagagt ttagaaaaaa aatataaaaa
    55561 gaatttatca ttgtatactt taacatctga tgacattata aatgtaatag ctaaaaaaag
    55621 tggcaaagac aaggcaaatc tatctataaa ttcacttcca caaatgataa aaaataataa
    55681 atactattat gctgaagtat atgagtatga taaattaata aatgaagttt tggtaagtgc
    55741 aaaaactaaa gatttatatt catataaaga tggtaaaaaa gattacaaag tagattatgg
    55801 tgatggatac tttagaatat tagaagatgg aagttatcaa tttggcatta caaaagataa
    55861 agctaagttt gtgttaacta atactctcga tgaaaaagaa aataagtata aaaagattga
    55921 gatattagat atagagaaag cagatagata tgtaaaaagt aaaaagagtt tagaagaatt
    55981 gtttggaaaa tataaaaata tttattatta tgctgtagta aataaaggct tatttagagg
    56041 caaagaagtt tatgctatta atatttacaa tgaaaaaata tatgccatat cagaaaatgg
    56101 actaaatgaa tattaataat attaaattaa tatataatta aaaagttttt ggggttttaa
    56161 ggcgcattat gtagtaatat aataataggg atatataaat aattttattg taaggagaag
    56221 tatgggatga gtaatgtgaa caaaaagcta gttatagcta ttggagctgt agcattagta
    56281 gtaataattt ttataggcat aatgtgcatg caatttaaag gggagaaaat agcaaaaaac
    56341 acatatgtta atggagtaaa tattggaaaa ttaactaaat cacaagcaaa acaggaatta
    56401 gctaaaaaat acaaattaga gaatgttgat tttaattaca atgataaaag ttggaaagta
    56461 aagagcaaag atttaaattt atctactgac ctggataaaa cagtagaaaa cgcatataat
    56521 ttaaatagaa agagtgcttt ctttggcaat ctatcaaaaa ctatttcagc aaattttggc
    56581 aaaaaaagca acttagtagt tgtgataaat tatgataaaa ataaattaaa agcagaaatg
    56641 gaaaagatag ctaaagaaat agatgtagat gtaaaagatg ctacacttga tataagtggt
    56701 gaaaaagtca aggttatacc agattctgat ggtcttaaaa tggatatttc taagagtatg
    56761 gagaattttg ataatcaaac taaaaaaggt aactataaaa atgagttagt agtaaaagct
    56821 actccagcaa aagtaaaaaa agagcaactt gctaatatag atacaaattt aggtacgtat
    56881 tcaacaacat ttaaaacttc tcaaataaat agaagtataa acataaaatt agcaacagat
    56941 aatataagta atgtattact tatgccagga gaaactttct catttaataa acatacaggg
    57001 aaaagaagta aggaaaatgg atataaaagt gcacctgtaa taatggaagg tgagatggaa
    57061 gaagattatg gtggaggagt ttgtcaagtt tcatctacgt tatacaattc tgtgttatac
    57121 gcaggtttag aaattgttaa tgtaaaaaat catactatac cgtcaagtta tgttccaaaa
    57181 ggaagagatg caactgttgc agatagtgga atagatttct tatttaaaaa taatctaaag
    57241 catccagttt acataaaaaa ttacgtttca ggaaatcaaa ttgtttgcaa tatatatgga
    57301 agtgcagaag ataaacaaaa tataacaata tcaacaaaat tagatggcgt ttcacaaact
    57361 acaatgaaaa gagttaatga ccctacaatg cctaaaggta aagaaaaagt agacaaaagt
    57421 ggaagaaatg catattctgt atcaacatat agaacattta atgatgcaaa tggtaaaaaa
    57481 attaaaactg aaaaaatagc taattcatat tatcctaaga aggaaggtat tatattagtt
    57541 gggactatgg aaccaaaacc agaggaaaaa ccaaatacag acgaaaataa gaataatcaa
    57601 aatacaaaca atcaaaatcc aaataatcaa caaaaaccag aaacaccacc aactgataat
    57661 aagcctaatg agacacaacc acaaccgcaa gcttaaagtt ctcaagaata ggatttatgt
    57721 agagtaataa aaaatataaa tctaaatagg agggattact ttgaatttaa ataatataac
    57781 gaattacgtt caaagtattt gcgagaatat ttctaatgtc ttggatgtag atgttacttt
    57841 agttacaaaa gatttaacta ggatagcagg tacaggaata ttcagaggta aaataggaga
    57901 gacaatatca gagaagtcag tgtactctct tgttttaaaa gatgggaaat cctatgttat
    57961 aaataaagaa atagaagaga actgtaataa atgtgcaaat agagaaaatt gtaaagagtt
    58021 agctgatata tgtactcccg ttaaaatggg agagcatata cttggaatct tgggtatagc
    58081 tgcgtttaat gaagaacaaa aagaaaagat actttcaaaa gataaggagt taactgcttt
    58141 tgtaaggagt atgtctgatt taatatcttt taaactagat gaactttata aacaagaagt
    58201 taagactata gatgaccttg agagggaagc tatagaaaat gccataaaga aatatggaag
    58261 taatacagaa ggtatgaaaa aagtagctga ggcattaaat ataggtatag ctacactcta
    58321 tagaaaagta aaaaaattca acattaaaag ttaatagtat tgaaaaagag gtaacctttt
    58381 tatgaaaaga agaggattac cttttttatt atgagaatgg tggaaaaata tgtatagttt
    58441 tgacttgaca tattaaatat gttatcttaa atatatattt tagagtggag gtgagtatta
    58501 ttttagttaa agatataaaa caagacatag aaagcatgcc tagaaaaatt ttagatatat
    58561 ctttgataga agataataaa agtgatttga ctttttttaa tatagaagaa gaagacggtg
    58621 atgaaacatt aaaagcatta aaacagagtt atgtgactac aaattataaa gaagaaactc
    58681 tattaaactt gcaaggagct ttaaattcaa agtcagatac aacgtctaag gagttaaaat
    58741 tagaatcata taaaagatat aacaatgcat tggatttagc atataaaaat tatataacta
    58801 gtgccattaa tatggttaat aaagctctgg agataaatcc taaagacatt gatatactaa
    58861 atcttagagg tcttttaaaa ttattaaaat gtgattttgc taaatcattt gagagttttt
    58921 atactgcttt atgttatgaa aataatcata tatctagaaa atatgtaaat ctaatttcat
    58981 ctgaagattt taaaactttt ttaggaagat acaatcattc tataagattt ataaatgaag
    59041 aattaaatta tgagtcaata catattttag agaacataat tgaagaagaa cctgaactaa
    59101 tagagccata tgtaatttta tctttgttat atgataaact aggtaatgta aaaaagagag
    59161 aaggatattt agacaaactt aaagagctag ataaagataa tcctgtattt gaaaaaaatg
    59221 aagaagaaaa agaagataca agtaaaaagg aagaaataaa aaaagtaaaa agaaagaaaa
    59281 gtattttgcc atatattata gttggctgtg ttttaatagg tatggggata tatttgattc
    59341 aaagcaaaaa gagaatagaa aacttgaata accaaataag tagtaaagag gaaaagttaa
    59401 gtgaaactga taaaaagtta ggagaaacga gtaaaaaatt agaaaaaacg aataaggaat
    59461 taaatgaggt taaaaataaa gaaccagaaa gagagataac tgtagctgat gaggaagatt
    59521 tatattatca agctctaaat ttaaagaaaa acaaagaata tgaaaaagcc atagataatt
    59581 ttaaaagtgt agtttcttct ggtaaaacta aaaaatatat ttctgagtca atatatcaat
    59641 tagcaataac aaataaatta ttaggaaata aggatgaagc tataaaatat tacaaaaaat
    59701 atataaatac ttatactaaa aatgaccagt attatgatga ttcatattac gagttgggta
    59761 tgctttatta tgataatggc gatttaaaaa atgcacaaca gactttttat agtttgagaa
    59821 gtgaagttcc agacagtatg tataacaatt caaaaataaa agaaatttta agtgaaaaat
    59881 aggtttatat agttaagttt tttgaaacaa ccaagtatgt attttattaa attaaaataa
    59941 aaataaattt aaaaagagat tgtgtcaaat tataactttc tattttaaag aaagatattt
    60001 gcttgttgat aaaactacaa atatatgatt tgaagcaatc tctttaattt ttggaggtgg
    60061 aaaatgaaag ttttcaatca attagtaata attttatcta tctgggtaat aggagagtat
    60121 ataagttcct ttatacaagg aattatactt attcctggga gtatagttgg tatgctatta
    60181 ttatttctac tactacaatt taaagtttta gacttgagta gtatagaaaa tgtaagtgga
    60241 tttttcctcg ataatatggc tatatttttt attccagcag gtgtatcact tataaagtca
    60301 ttagacctaa taagggaaaa tgtattagtg cttttattag tcatatgttt aagtacacta
    60361 atagtaatgt atactactgg aattattgtg gagaaaatga taaaaaagaa ggaagaagga
    60421 caaaaaaatg tataatgtat tacagacacc agtatttggt ataatagtaa caatagtttt
    60481 tttcaattta ggaagataca ttcaacgaaa aacaagtaat cctatatgta accctttatt
    60541 aattgcaatc gtaggaataa tattgttttt aagcatatct aaaatccctt atgagaatta
    60601 caagatagga gctgatagtc taaatttctt tttaggtcct gtcacagtag tacttgcagt
    60661 tccactttat aaacaatttg aattatttaa aaagcatatg tttgagatta ttgtaggaat
    60721 aggttgtggt atagtgattt cttttgtatc tgtattgata attggcaaaa tagctaattc
    60781 agatgtaagt ataataaatt cactaattcc aaaatctata acaacaccaa tgggaatatc
    60841 tttagcaaat tctttaaatg gtatagaatc aataacagtt gtagccataa tttttacagg
    60901 tatttttggt ggtatggttg cttctacagt attcaaactg gggaatataa atcatccagt
    60961 tgctaaagga attgctcttg gaacatctgc acatgcttta ggaactacaa aggcttttga
    61021 acttggagaa atagaaggag ctatgagtgg tgtttctatt ggagtctctg gtacaattac
    61081 agtaatacta attccaatta taatgaattt tatataaaaa ataaaattaa gacgagtacc
    61141 ttgaatactt aaaacaaaat aaaataaaaa aaatttaaaa taaaaactga acgaaaaaaa
    61201 tgcaaataat gaaataaaaa aatcatgtac tgaaattata aaaagaaaaa tttcatttag
    61261 gaattaatta taaagagaca attactaaac ttgaatttgc taaaataaaa taaattactg
    61321 cgaaaataga tatttagaaa aaaatactat aaatttacta tattgcaagt taaataataa
    61381 gcagtatcat attatgctag aaaaagtttc atttaaggca taaatgagat gatttgaacg
    61441 tttttaaaga ttagaatata aaagattgca ctagacatat atgaaaaaga taatataata
    61501 gatgatgtaa tagatgacag ttcaagaaat tataaaaaaa atttatttga aatattatct
    61561 attacatcag gaataatata tgtaagagta agcttttaaa attctaaaga tttagaaaga
    61621 ttgaagggag aaagaaatga gtgaagttaa gaatacccta caaaaacatc cagttttaag
    61681 atattcaaca atgctatttg ggatgttgat gacatctata ggaataaatg ggttcttaag
    61741 accagcacat ctacttagtg gaggtgctac aggtatagca acatctataa actatttgac
    61801 aaatataaat gtaggtttat taacattttt aatcaatatt ccaatattta tcttagggtt
    61861 catatacctt gaaaaagagt tttgtatttc aagtttggta aatatgattg tattttcatt
    61921 attattagga gcaactcagg aaataagtaa tattatacct atacatgata tattgcttca
    61981 aagtgtatat ggtggtatat tatctggttt aggagtcgga gttgtattta gaactaggtc
    62041 ttctcaaggt ggtacagata taatagctgc aatactaaaa attaagaaga atatagaaat
    62101 gaaagacact gctttagcaa taaatggctt gatagtactt acaggaagtt ttttatttgg
    62161 gttggattta gcattataca ctcttatagg tctatttcta aatgcgtatt caatgagttt
    62221 tattaaagat gcaatgaatt accaaaaatc tgttatggta atgtcaaatg aagtcgattt
    62281 aatagcagaa gatataatga agagtttagt tagaggtgta acttttttag atgcagaagg
    62341 tgcatacact catcaaaaaa agaagattat atatacaata gtttcatcaa atgagatacc
    62401 aaagataaaa gatatagctt tgaagtatga taaaaaggcc tttatatctg taaatgatgt
    62461 tacagaagta aagggaagag ggtttaaagc aaaagattta tagaaaattt tacaagctgg
    62521 gagtttataa tgtaaatttg tatattatat ctctcagctt atttaaattt agtatacgaa
    62581 aataaaggtt ttattaatga tttgtgtatc actttaaaag atatcatttt aaaattaaaa
    62641 ttgaaaaaat tacttaatat gtagaaaaca tgaccactat taggatataa taaatttaat
    62701 agatttagta aaatatctag gaataacgtt ggaggaatgg cattatgaat ttatctaaag
    62761 aatatgttaa tttgtatgat aattatttga aatatataaa tgaagtaaac aaagagatta
    62821 gaagtataaa gaacatgaag aaacgtgttt taaaaagggg cgattttgct ccagaaaatg
    62881 aagtattaga attggaagga aaaacaatac gcgatataga tgatgtcgat acaaaaaaac
    62941 caaaaaataa aatctataaa ttttcaaatg gggatgtata tgtagggaaa ttcttagagg
    63001 gaaagatgga ggggaaaggc tcatatactt tttttgtaga tgaaggaaca gttatggagt
    63061 acataggaga atttaaagaa gataaaaaaa atggaaaagg aaactttata ttttcaaatg
    63121 gaaatgaata tataggttat tttgaggaag atatgatgag cggtattgga aatatgttat
    63181 atagtagtaa agatgaatat attggaactt ggaaaaacgg aaaaaaagat ggaaaaggta
    63241 tttataagtg gagtgatgga tgtatatatg caggtgaatt taaaggtgga aagatggaag
    63301 ggtacggtat ttgctataat agtaaagggg aagtacttta tgaaggagaa tggaagaata
    63361 atttgattca tggtaaggga acttatatat gggaaaaagg taaaaagtat ataggtgaat
    63421 ttatgcatgg taaaaaacat gggcaaggaa ctttttatct aaataatgaa ttggtttatg
    63481 aagggacttg gaaatttgat aagccatcta tatttgatag aacattagat gaaatatttt
    63541 ccttgagact gtagctttat ctaattagta gataaagctt ttttctaata cttactgtaa
    63601 ataggtatga atgatattga ttagtataca ctatcaatat taacttaata aatgcaatat
    63661 taaaaaattt tgattgattt taagaaggag agatatattg aagagattaa ttgctttagt
    63721 gttagtagta cttattgttt tattttatag tcctgaatta ttaaaagaag gatatgattt
    63781 aaaagaaaag ttttttcaaa gtgaaatatg gaatgaattt ttagacaaaa taaatataaa
    63841 tgataattct aagaaagata aaaaagaaaa aagtcaaaat ttacaatcaa ataatactga
    63901 aggggagaac ttaggagagt cagatataaa gaattttgaa aaaataagct taggagataa
    63961 tttaagctat gttttatcaa gtattggtaa acctggtaga attgatatta gtgaatatgg
    64021 ttttgattgg tacgtatata atcaatatgg aaaagaattt gcaatggttg gacttgaaaa
    64081 tgatgaagta gtagcacttt atagtaattc tattaattca tgtgaaaatc aagatataaa
    64141 actaaatcaa gatagacaaa cagtgagaac taagattaca ccattaaaat ataagagaaa
    64201 aggaaatacc agatatataa taaactcaga aaatcaatat gatataataa gtaaggaagg
    64261 taagtatatt acaattttct acgatattca tgaagaaaat agagtctgtt catatttaat
    64321 aattgataaa agcactgaag atgagtttaa aaatttatat ccagatgata gcgaagaact
    64381 taaaaaatgt tttgaacttg aagttataga ccttgtaaat agtgttagaa atcaaagagg
    64441 gttaaactca ttgagataca gtgaacaggc aactttgagt tcaataaaac atagtgaaga
    64501 tatgagagat aataattttt ttgaccatgt aaataagaag aatgaaactc catttgacag
    64561 aatgaaaaga gaaggtatag tatatacttc agctggagaa aacatagcag caggacagat
    64621 taatgcaata tatgcgcatg aagcttggat gaactctgaa ggacatagaa aaaatatttt
    64681 ggggaactat aataatattg gagttggagt aatatttgga ggaagctata aaacatatta
    64741 cactcaaaat ttttataaat aactaaaata tttgaaagga agttaaaaaa tgacatcatg
    64801 gaaaaaaaag acagtatata agtgcttaat agcagtagtc ttgttttgtg gaatagtgtt
    64861 aatatctaat tttagtaaag tttctgcttt gatgatggat actaatggaa atgttttgat
    64921 taaacatggt tcaagggaaa aaaagctaat agcaattacc tttgatgatg gtcctcatcc
    64981 taaagaaact agtcaagttt tagatgtatt aaagaaatac aatgtaaaag ctactttttt
    65041 tatagctgga aaacatgcaa aatggtataa agaaccatta gtaagagcaa gtaaagaagg
    65101 tcacgagata ggaaatcata ctttcaatca tcctgatata agtaatttaa gttctagtca
    65161 gatagaagag gagattgtta agtgtgaaga cattttgaaa gaagtaactg gaaaaaaacc
    65221 gacattattt agaccaccat ttggaagtta tagagaaaaa gaattaatag aaattgcaaa
    65281 aaagcatgac tataaagttg ttttatggac aggtgtagat gtgaaagatt ggaaaaatcc
    65341 aggagctaat agcattgcag ataaaataat taataaagta caaaatggag atataatact
    65401 tttgcatgat tatgcaacta atgatacagt tgaagcttta gatatgttta ttccaaaaat
    65461 gattgaaaaa ggttttaaat ttgtaacagt ttctgagttg ataaaataat ttttaggggg
    65521 gagatttaca gtatgattct tatgatagac aattatgatt cttttgtata caacctagtc
    65581 caatatatag aagaattagg ggaaacagtt gtagtaaaaa gaaataatga aatcaaaata
    65641 agtgacattg aagaactaaa tccagaggta attgtgttat ctccaggacc gtgttctcca
    65701 aaagaagctg gtatttgcat agatattgtt gagcatttta aggggaaaaa acctatacta
    65761 ggaatttgtt taggtcacca aactattgga catgtttttg gaggagatat tataaaagca
    65821 caacagcctg tgcatggaaa agtatatagt atcaaccata ctaataaagg agtttttagg
    65881 ggacttaaaa atcctttaaa tgtcactagg tatcattcac taatagttga ctccaataca
    65941 gttccaaaag aattagaaat tacagcaatt actgataaag gggaaataat ggggattagg
    66001 cataagaaat atttaataga aggagtacag tttcatccag aagctatttt gtcagagtat
    66061 ggtcatgaaa tgcttaaaaa ttttataaca gaagctagag aaagggtaca tatgtaatat
    66121 gataagagag ataaatacta aattaaattc ttttgagata tttactattt ttagaaatga
    66181 acatgacagt tttatattag acagtgctat ggataaagaa aaattgggaa gatattcttt
    66241 tataagtagc caaccattta aggtattaaa gtataaagat actgatgaaa atcctttaga
    66301 agttttaaaa gaagaactac ataagtatag ggttgtaaat gatactaatc ttccatttgt
    66361 aggaggtgct gtgggatatt tatcttatga tttaggtaat tacatagaaa atttacctag
    66421 aactgctgta gatgatattg agatgcctga tatgtatttt ggattttata atcatgtaat
    66481 agttatagac catcttgtgc aaaaaactta tatagctact ccaaacatag atatcgaatt
    66541 agaagaaaag ataatagatg atatagaaca aagaatatta aaagaagaga aaaaaggtat
    66601 agatagcata tgttatgaag aaaaagaagt aacatctata agacttaaat ctaattttac
    66661 aaaggaagaa tttaaaaatg cagttcaaag tgttagagag tacataagac aaggagatat
    66721 atatcaagct aatttaacac aaaggttcag tggagaaaca gaacttacaa gctttgaatt
    66781 gtatagggac ttaagaagat ttagcccagc accatttggg gcattcttaa actttgaaga
    66841 tgcacatata ttatcaaatt ctccagaaag atttataaga tgtgttaata agagaataga
    66901 aactagacca ataaaaggta ctcgtccaag agggaaagat aaagaagaag atttaagact
    66961 tcaacaagaa cttagaaata gtgaaaaaga tagagctgaa ctacttatga tagtagattt
    67021 agaaagaaat gatattggga gaatatctaa aactggaagt gttaaagttc cagagctatt
    67081 tgtaattgaa ccatatgcaa atgtaaatca cttagtttcc acagttgtag gtgagttaaa
    67141 agatgataaa gatgctactg atgtaataaa agcaactttt ccaggggggt ctataacagg
    67201 agcacctaag attagagcaa tggaaattat agacgaatta gagccaacgc aaagaaatgt
    67261 atatactggt tcaataggtt atataggttt taatggtgat atggatttta atatagcaat
    67321 tagaacaata atcaaaaatg acaaaaaagt ctactttcaa gttggaggag gaatgacttg
    67381 ggattctgac ccagatgaag aatatcaaga aacacttgat aaagctaaat ccataatgaa
    67441 ggctttgagg ggatattatg aagaataatg taggttttga tagtagttta agtaaatttg
    67501 gaattggttt gtttgaaact attagagtta aaaatggaat agcagtagat ttagatatcc
    67561 atatagaaag aatgctaagc tcaataaatt gtttggattt agatataaac tatacaaaag
    67621 atttcttgat aaatgaaatt gttacatata taaaaaaaga aaatgtcatt aataaagcac
    67681 ttagaattac tgtttttgat gaaggttata atatatctat tagggatgtt ccatataatc
    67741 aagagacgta tgagaagggg tttaaattag ctatatctcc aatagttagg gggaatagtt
    67801 taattcatag acataagact actaattatt ttgaaaacat atataccaaa aatatcgcaa
    67861 ataagactgg ttataatgat ggtatatttt taaattcaga aggtgtaata ttagaatgtt
    67921 ctatgagcaa tattttcttt ataaaaggag aaagagtgta cactcctagt gatagattac
    67981 cgatattaaa tggaataata aaaaaaagga ttatagagat ttgtgacgaa ttacatatag
    68041 agttgataga aaatgaaatt aatatatcag aaattagtag ttttgatttt gtttttgtca
    68101 caaatagtct tatgggcgct ataaaggtta cagaaattga caaaataaaa tttaataaag
    68161 aaaatgttgt ttttgataaa atagtgaagt tattagaata aattaaaata ttaacaattt
    68221 gttggagaca aaagatgata ggttgtattt atgaagtata caatgaagag ataactaaaa
    68281 taatagaaaa ccaaaacact ttggctgtat atttagtggg ttctagtaaa gacgtagatt
    68341 ttactcttta tgatgtagag ataaacgata ttgatgtgtt cgtttttgta aaagaagggg
    68401 aaaaacaaga gagaatactg tttaaaaaaa agggaataga atttgatgta aattactttt
    68461 caaaagatgg tgtaaaaaaa ttattatcaa atagggaata tttctttgtg aaagaaatga
    68521 aagatgctaa agtactgttt gatagggaga atatatcaca tattataaaa gatataagta
    68581 gaaatattta cttagaagga cccagtaaaa tgtcattaga ggaaaagtct tttataaagc
    68641 aagatattgg agcaaaaata tcgaatttaa aaaataaaga aaaatttgat gtttttgaat
    68701 atcatttttt gacgaattta tatttaaaag atataataat tgggtacttt aatataaatg
    68761 ataaatgggt accaaaagac aaaaaattgc taaaagtttt aaaaaaagaa aataatgagc
    68821 tttttgaact agtgtcaaaa gtaagtgaaa attatgacta tcaaagactt ttagatgttt
    68881 ataattatat ttttaaagaa attgagacaa aagaggttat aaaactaatc ttctagtcac
    68941 aaatcaatgg ggggagttta aatgaataaa gttgataaag aaaagataca acatgcagta
    69001 agagaaatac tagaggcaat tggggaagac ccagatagag aaggtctaat cgaaactcca
    69061 aatagagttg ctaggatgta tgaagagata ttctctggtc ttagtgaaga accaagagac
    69121 catttaaaag ttctttttgc agatgaaaaa catgaagagt tagtattggt aaaagatatt
    69181 ccattttatt catgttgtga gcatcatcta gttcctttct ttggaaaagc tcatattgct
    69241 tatttaccaa aaggaggaag acttacaggg ctttctaaac ttgctagagt aatagataca
    69301 ttggcaaaaa gaccacaatt acaagaaaga atcactaaaa atgctgcaga tataataatg
    69361 gaagaattac aaccttatgg tgtcttagta gtagtagaag ctgaacatat gtgcatgaca
    69421 atgagaggcg taaaaaaacc aggttcaaaa actgttacat cagcagtgag aggaatattt
    69481 gaaaaggaca ttgcgtctag agccgaggct atgagtttga ttactatgaa gtagcaattt
    69541 attatagata taatcattta ttgagataaa atttaattta agggagtgtc attaattgtg
    69601 tttgattatg gtaaaagaac ttatataatg ggaatattaa atgtaactcc agatagtttt
    69661 tctgatggag gagattttaa taacttggac atagcaatac aacatgcaaa agatatggtt
    69721 gaccaaggtg cagatataat agacctagga ggagagtcta cacgcccagg tcatagctat
    69781 gtagactcag acgaagagct aagaagagta atccctgtaa taaaaaaact taaacaggaa
    69841 ttggatatac caatatcaat agacacttat aaggcagatg ttgcagaaga agcattaaaa
    69901 ttaggtgtca ctatggtaaa tgatgtttgg ggccttagaa aagataaaaa tatggcttct
    69961 gtaataggaa aatatgatgc agaagtgtgt ataatgcata atcaagatgg gacaaactat
    70021 gacaaagata taatggagtc aataaaagac ttttttaagg taagtataga aatggcaatg
    70081 agttatggtg taaaaaaaga aaaaatagta cttgacccag gtgtaggatt tggcaaggat
    70141 tttgaacaaa atattgaagt attgagaaga ttaaatgaat taaaagattt agggtatcct
    70201 attttgcttg ggacatccag aaaatcagta ataggaaaag tacttccagt tgagcctaaa
    70261 aaaagattag aaggtacaat agctactact gttcttggta taagagatgg cgtagatata
    70321 gttagagtac atgatgttta tgaaaattta atggcagcta gaatgactga tgcaatatat
    70381 agaaagtagg tataatataa tggataaaat attacttagt aatctaggat tctatggata
    70441 tcatggtgtt cttaaagaag aaaattttct aggtcagaaa ttctttgtcg acatggaact
    70501 ttatattgat tcaagagaag caggtcttag tgacgatata aataaatctg taagctatgc
    70561 cgaggtttac aatgttgtta aagatattac tgaaaataaa caatttaatc ttttggaggc
    70621 tttagcggaa aatattgctg aagaagtctt gaataaattt atacttataa atggagttag
    70681 ggtcagagtt agaaagcctg aggctcctgt aaatggtatt tatgactatt ttggtgttga
    70741 gataaggaga gcaagagatg aataaggctt atttgggaat aggtactaac atgggtgata
    70801 gatttgataa tttatcaaga gcatgtgaac ttttgaaaaa tagtgattct atatataaag
    70861 taaaagaatc aagcttatac gaaacaaaac catggggata tacagaacaa gcagattttc
    70921 taaatatgtg tgtagaaata gaaacagagt ttgaacctta tgagttgtta gaatattgtc
    70981 aagaaataga gagagaacta cacagagaga gaatagttca ttggggacca agaactatag
    71041 atgtagacgt actatttttt aatgatgtag tttccactga tgaaagacta acaatacctc
    71101 atccaaggat tcaagataga gctttcgttt tgataccact tatggattta aatgaaaaac
    71161 ttataataaa tgaaaaaaca ataaaagaac atttaaacct cctatctgct gaagaaagag
    71221 aagaagtaaa ggagcttgta ggttatgaaa gaaaacctat ttaataataa ttcaaagata
    71281 gagataaata caaataacaa aaagataact gtaaaaaaag ataaacttat aatagctgga
    71341 ccatgtgcaa tagagagtta tgagcaactt ttggagactg ctaaatttgt aaaaagtcag
    71401 ggagcaaata ttttaagagg tggagcatac aagccaagaa catctccaaa ttcatttcaa
    71461 ggattaaaaa aagaaggtct tgaaatatta aaagcggtta aagacgaagt tggtatggct
    71521 gttattacag aacttatgga tgtaagagat atggacgaac tgtatagtat aagtgatata
    71581 attcaaattg ggtcaagaaa tatgcaaaac tttactcttt taagtgaagt gggaaaacaa
    71641 aataaacctg ttatgttaaa aagaggaata gcatccacaa ttactgaatg gataggtgct
    71701 tctgaatata tagcaataga aggaaatagt aatattataa tgtgtgagag aggtataaga
    71761 acgtataatg attatactag aaatacatta gatttagctg cggtacccat tattcaaaag
    71821 gaaacaggtc ttcctgttgt ggtagaccca agccatgcca ctggagttag atatttggta
    71881 aaacctatgt cactggcatc ttttgcatgt ggagcagatg gaataatggt agaagtacat
    71941 cctgacccag aaaatgcttt gtcagatggt gctcaatctc tttgctttaa tgaatttgaa
    72001 gatttaatga aatcaattaa taattattaa aagaggcaag agcctctttt ttattcgtaa
    72061 tcgttgctga ggtaaattta taagttataa tttgatagtt agattattta atataaataa
    72121 agatttaata ttgatagaat taatataaaa aataaaaatt ttttgattaa taagaaggat
    72181 atcaataaaa aaagtcgaat tgtgtatatt gagtgattga caaatttaga atatagtgta
    72241 gaatagaaat gttaacacaa aaaattacac cagaaggtga taatatgaat gatataaaag
    72301 acattattga agaaataaaa gctagatgcg atatagcaag tataatatct gaatatatga
    72361 atataaaaca atctggagct aattacaaag gattatgtcc atttcatggc gaaaagacac
    72421 cttcttttta tataaataca tcaaaacaga tttataagtg ttttggttgt ggtgaaggtg
    72481 gagacgtaat aaattttgtc atgaaaatgg aaaatttgga ttttatggat gctgtaaaaa
    72541 ttttagcaaa taaatgcggt atagaaatta atactaacat gaatgaagaa actaggatta
    72601 aaatagaaaa atctaagaaa tttcaagata ttcatacgga agcagctaga ttttatcttt
    72661 caaacttatt gggaagcaaa aatcttgggt atgaatattt aagaataaga ggactagatg
    72721 ataaaattat taagaaattt ggtttaggat tttctttgga ttcatggaat tcacttatga
    72781 atactctaat cagtaaagga tataaaaaac aagacttatt ggagtgcggt ctaattgcaa
    72841 aaaatagaga tggaactaat tgctatgata aatttagaaa tagagttatg tttcctatat
    72901 tcgattatag aggaaatata ataggatttg ggggaagagt attagacgat tctttgccaa
    72961 aatacttaaa ttctccagac acattaattt ttaataaaaa acagaactta tacggattaa
    73021 attttgctag aaaaaattta gaaagtaaaa ctatagtctt agttgaagga tatatggatt
    73081 taatttcact ttatcagtat ggtataaaaa atgtagtagc aacccttgga acagccttga
    73141 ctgaacaaca aggcatttta ataaagagat atgcggacac tgctattata tcttatgatt
    73201 ctgatgaagc aggaataaaa gcgactttaa gagctataga tatacttact aaattaggta
    73261 tcaatgtaaa agtgttagac ttaaaagatg ctaaagaccc agatgaattt gtaagaaaat
    73321 acggacttag tgattataaa aaagctatgg atgtttctac tcactacata aaatataaaa
    73381 tagatcatct taaaaaagaa tttaacattc aaaaagatga agaacgagtg aagttcgcaa
    73441 aagaagcttc taaaattata aaacaattga caagtcctgt tgaaattgat ttttatacaa
    73501 agtatttaag caatcaaata gatattaatg tcgagtctat aaagagagaa gtttatggta
    73561 aaaattacaa taagccatat aataacaaaa atcaaaagaa aatagaagaa aaagtaattg
    73621 aaaaagtcga agtcagacaa gacggaaaac aattagttga agaaactcta ataaaaataa
    73681 tgttagaaga caaaaaaatt agagaaatag cgttacttaa agtagaagaa agtgattttt
    73741 tattgaaaga aagtaaagaa attttaaatt acatgattaa aaatcaagaa ttggacaaaa
    73801 taactattga caaattgaaa agtttaaaca tatccgaaga atacttaaaa gaattaaatt
    73861 caatttcttt gaatagtata aacttagaga acacaaaaga aatagaagga ataataacaa
    73921 atatcagaaa aaactcatta gaagagcaaa ttaatagctt gttgagagaa caacaagaat
    73981 tagaaaataa taatgatatg aaagaggtag atggtagagt tatggaaatt gctttaaaaa
    74041 tagttgagat aaataaaatt ttaaagagct tgtagagaaa ggaggtttga gtgtggaaaa
    74101 taaatcgaat aaaaaagagt taaaaaaggt tactgctaag acattaatag aaaaaggaaa
    74161 aaagcaaggt tctctgacac ttgcagagat aatggaagct ttttcggaga ctgaacttga
    74221 taaggatcaa gtagaaaatc tttatgagac tttaggaaat ttgggaatag aaataacaga
    74281 aacaaaaaac tataaagctg atatagattt ttcggttgct gatgacgatt taagtatagg
    74341 ccacttagat gaagatgcag aggcaatttc acatgatgac tcttctgcaa tagaaataga
    74401 aactgtggat ttatctttac caaaagggat aagtatagat gaccctgtaa gaatgtactt
    74461 aaaagaaata ggaaaaattc ctctacttaa accacatgaa gaagtagaat ttgctagaag
    74521 gatgcacgaa ggtgatgaga tagcaaaaca aaggttagtt gaagcaaact taagactagt
    74581 tgtaagtata gcaaaaagat atgtaggaag aggtatgctt ttcttggatt taatacaaga
    74641 gggaaattta ggtcttataa aagcagtcga aaaatttgac tatacaaaag gatataagtt
    74701 tagtacttat gcaacatggt ggataagaca agctataaca cgtgctattg cagaccaagc
    74761 tagaactata agaataccag ttcatatggt agagactata aataagctaa taagagtatc
    74821 aagacaacta cttcaagaac ttggaagaga tccaaaacca gaagaaattg caaaagaaat
    74881 ggaaatgaca gaagataaag taagagaaat aatgaaaata gctcaagacc ctgtgtcttt
    74941 agaaacacca ataggagaag aagaagatag ccatttaggt gactttattc cagatgatga
    75001 tgctccagcc ccagcagagg cagcagcata ttctttatta aaagaacaaa tagaagatgt
    75061 acttggttca ttaaatgata gagaacaaaa agtattaaag cttagatttg gtcttgagga
    75121 tggtagagcc agaactcttg aggaagttgg aaaagagttt gatgtaacta gagagagaat
    75181 aagacagata gaagcaaaag cactaagaaa actaagacat ccaagtagat caaaaaaact
    75241 tagagattat ttagactaaa aagatacatc attgatgttt ttgtgataaa tgccatgaga
    75301 taagtgatat ctcatggcta ttttgtagta aagatttaat tttatttttg tagttatttc
    75361 agtctaatat ctataacttg gattaaatcc tataaataaa gggaattgaa aggagaatta
    75421 tatttgaaat taacagatag attattgaaa atagcatcat tagcgtcaga tggtaaaaaa
    75481 atagctgata tagggacgga ccacggatac ataccagtat atttgttaaa agagggaaaa
    75541 gtaccatttg cagtgctagc ggatgttaat aaaggacctc ttgacaatgc acataaagaa
    75601 gtcatacaga acaatctttt agataaagtt gatttacgat tgggttctgg tatagagata
    75661 cttgaaatag gggaagtaga agaagtgata attgctggta tgggtggaat cttgataagt
    75721 gagcttctcg aagctaaaaa agaagtagca cataatgtag aaaaattaat attacagcca
    75781 atgcaagcac aagaagaact tagatattac cttttaaaca acggatatga aattttagaa
    75841 gaagttttag tgagagaaga ttttagaata tatgagataa ttgttgccaa atatacaggt
    75901 aaaaatacta taatagaaga tgagatatat tatgaggttg gaataaagct tttagaaaac
    75961 aaagattctc tttttaatga ttttatagaa aaaaagataa agacatatag ttctatagtt
    76021 aataaattag aagggaaaaa tggggaagct atagataaga agagaaagga aagcgaagtt
    76081 gcaataaaaa aacttgaaaa tttaataaaa taaataggag gtatatatgc tattaaagag
    76141 tctaactaga aaaattgaaa aaaagtatcc tctaaactta gcagaggatt gggataatgt
    76201 aggtcttata gttggagatt ttgatatgga tgtaaaaaag gtattggtat ctttagaagc
    76261 taatgaagat gttattgatg aagctatatc caaaaatata gatttaattg tgacacatca
    76321 tccttttata tttgggaaaa ttaataaaat taatagtgga gatttaaaag gcagacttat
    76381 ccaaaaactt attaaaaatg atatatcact ttattctatg catacgaatt ttgatatagc
    76441 atttgatggt ctaaatgact attttatgga aattatggaa tttggtaatt caaaggtttt
    76501 agatataact aaaagcgaaa atttgtataa attagcagta tacgttccac ataactattc
    76561 agatgaactt agaaaggttt taagtaattc aggagcaggt catataggga attatagtga
    76621 ttgtacgttt tcaacagaag gtgaaggaca atttaagcca ttagaaggct ctaatccgtt
    76681 tcttggaagt gtaaatgata tagaaactgt aaatgaagtt aaaattgaaa ctgtagtacc
    76741 acagaagctt ttaggtgggg taataagttc tatgttagat gcacatcctt atgaagaagt
    76801 tgcatatgat ttgtacaagt tagaaaataa aggtgagata tttggactag gtagaataag
    76861 taaacttgat aaaagtatga cattagaaag tctttcaagg aaaataaaag agaaattaaa
    76921 tatgaaacac ataagagtag ttggaaacct tagtacagac ataacgaaag tagccgttgt
    76981 aacaggagct ggttcagaat ttgtaaaaaa agctaagaga caaggtgcag aagtactaat
    77041 tacgggtgat gtaaagtatc atgaggcaca agatgcactt gatattggaa tgtgtatagt
    77101 ggattgtggt cattttgata cagaagatat attcaaaaat gttatgaaga gatttttaga
    77161 tgaatttagt gaaattgaag taataaagag taatgtatat ttgaatccat ttagtactat
    77221 ttagcagtgt ttgataataa aaatactata taaaaaataa atttgagttt aattaggggg
    77281 ataatgatga aagtagcagt aatttttcat agtgtttgtg ggagtacata tttattagct
    77341 agagaatata aagaagcgct tgaagaaatg aatatcgagg tagatatatt tagagtaagt
    77401 gacgaagttg caaaaacact tcctcaatat tatttgataa attccaaaga atacaaagac
    77461 gaatttgaaa gtataaatgt aattaaatct ggaaaagaaa tattagatta tgatgctata
    77521 tttatgggtt caccaacata ttatggaaat gtatctggac caatgaagat gtttatggat
    77581 agtttttctg atatttgggt aggtgctcct ttgagtggta aaatatttgg ttgttttgct
    77641 acagcaggtt cacaacatgg aggaggagaa ttagctttgc aagctatgaa tatatttgcc
    77701 caacatatgg gaatgactct tttgtcagtt ccatgttcag taagaggagg ttatccagcg
    77761 tatggaatac ttcatatagc aggagataat tctgatataa gaccaaatga tgatgccaag
    77821 atgggtataa gagattatct aaaaagactt aacatataag aatatcatat aaaaatacct
    77881 aaaagcgact gtatatactt ttaggtattt ttacttaatt ataaacgtga agctttacca
    77941 gaaatatggt caatttctat tttaacaaca gttgttaagt tcatatcctt ctctatgtac
    78001 ttcatgcctt cttcaaagaa tcctttagaa tattttttta ttatttctac aagagcattt
    78061 ttcttttctt cattttctac agtgcaagct tttccaaaaa ctatagcact agaataagta
    78121 gtactaaatt tatctggaat aacactttca ttagcaacta ctaaaaaaga aactttgttg
    78181 tttttcgata tattatctaa cttatgccca tttcttgcac aatgaaagta aatagaatca
    78241 ttaaagtata cataatttac agcaactcca taaggataac cattttcaga tatagtggaa
    78301 aaagtaccaa attcaccatt ttttaatact tcaacagtat cttcttttgt catttctctt
    78361 tttttcaatc tcatttcttt aaacataata tcatcctttc taattttgat gcttaaatta
    78421 aattttagca catttataaa gattatgcta tgttttttac aaattttaag aaaaaaatat
    78481 agtttaagat aaaaggtagt gaaagagaag ctatttggag gtttatttat gatattattg
    78541 ttagagtagt ataaacaata ctaataaatt taatagctgg tttcttgtta tttaaggtag
    78601 taagcatgtc tataagaagg ggaagttatc gagggtagaa gttgttattt ataacgatat
    78661 tataaagaaa atattattat ataaaataat aaatagtaaa gaggtatcaa gttgaatata
    78721 atacttaata cctcttcaaa attaagttat aaaagtgttg tgggaattgt cctatacatg
    78781 gtaaggagat aataaagaat gtatctttaa agtctcaact aaacagcaaa atttatccaa
    78841 caaacataca ataaatgctt ctttgtatct aggtggctta acagtaagtg gccacatgtg
    78901 ttttaaaatt atgtccgttt ctttttcatt tatttgaaaa aataaagttg cattttttaa
    78961 tgcttctcta gggtgagtaa atccatgtaa tccttttcta tcacctttgt aatgccaatc
    79021 ataaagaaaa aagtcgtgta gtaaagctcc tctaataaca ctttgaatat caacacttaa
    79081 gtgcaatttt ttacataata gataactata atatgctact gacaaactat gttcaagaca
    79141 tgaaacattg ccatgatgag gaaatgttct cataagttga actttttcag aagaaagtat
    79201 ctcagaagca cattcattaa aatatttgat ttcagctttt gacaacatta tgaaaatctc
    79261 cattcttagt aatatataaa tactatactt caacgataat atgaaatatt tcttatccta
    79321 caaaatataa tacccaataa tacaagtaag atacctttta tggtatttta aagtaagaga
    79381 gattttatta ggctaaacaa tgaaaaaatt aaaagtaaag ctatagcaat atatagtatt
    79441 tttccaagag gattgccaaa atttatagtc catccaatac caaacctttt attaaccatt
    79501 aatgatgggt catttggatt attatacatg atgcctgcta tccaatactt ctcatcttct
    79561 tctggagaat aagatgagtt gaattttaaa tttggggaat taatatatgt tgctattaaa
    79621 taaattataa ctaaaagcgt tgtaatattc atagcagttg atagttttgt ttttattgat
    79681 aaaagagtag taaaaaactg tgttgtcatt ataatcatca atattaaaaa caaataacca
    79741 attttattta aatatttaat gttttcaact ctactttctt caattctatt tgtatctatc
    79801 ttaatccttg actttatgga tccaatggaa gttatatata ataaaaccat taaacaaaag
    79861 tcagtaccga ttaatttaaa tacattaaga aatgatttat ctataaaaac atcaggagac
    79921 ccatttatgt tccaatgagt ggcaattgag tctggcaatt gattataatt aaatgctata
    79981 aaaatactca ttcccaaagt aaatagtatc ggtattaaat agattatttt aaattttttt
    80041 attattttat ttttcttatt tataaaatcc atatctacta ttaattttga atctatatct
    80101 atatgaccta atttagcata aatttctaat ttaagcttct tagctttttt atgtgtatga
    80161 atatatagta tactttcata taataaaaaa cctataatac caataaaata ggaaagttcc
    80221 aatttattaa atgtaaaaac cagaataaaa actaatataa agtctataat aaaacctaaa
    80281 gataatagtt ttttaaattt tttatctaac tttataaagt aattataatt tttatgctct
    80341 tggtctatag aaactccata gatgtgtttt ttacctacaa aatagggcat aaaataaaat
    80401 gtagcataca tcaaaattag aactggaaat attgtaaata gacattcaat cttactcata
    80461 atatttcacc tcatacttgt caaataaact tgaacttagt gacaaaaatt cttctttact
    80521 aatacctgat aaataagatt ttgccaccaa taattccaag tcaagtttat ttttttgacg
    80581 agttgtatta tctattttca ttggtagttg agctacaata gcaccttttc ttctatcaat
    80641 atttaagaat ccctcttctt ttaattcatt gtaggatttg ttcactgtat gtaaatttac
    80701 accaatattt tcagccatac ttcttacaga tggaagtgat tcatttattt tcaattctcc
    80761 tgaagctata gccttagtta tttcttcttt aatttgtaca taaatagatt tatcactatt
    80821 aaaatctaaa tttaaaacca taaaaaacct ccattatgct ttataaatga aaacgattgt
    80881 tatatacata gtataacata aaaaataata acaaacacaa aatataagtt tatattttgt
    80941 aaaaattgta atttaaaaaa taacataatt tttattaaaa taatacagat actatttata
    81001 gatagaaata aaaattagaa aggagaaaaa atatgttaac atatttaatg aaaagacaaa
    81061 tgcataaaaa agatgatgga atgagtaaac caatgatgat tacaggagct gtaattacag
    81121 gtgtaggagc atatgctgta tataaaatgg taaaaagcca taaatctaat tctcaaatgg
    81181 tcaatacaaa ttattatgga aatagcgatt atgatgatta taaatatgac gaatttgatt
    81241 atgactgtga ttgtagagac acaaaacaag attatgaata tgaagaatta aaaaaaaaag
    81301 taaaagaatt taattcaaga agaataaatt gtgaaaattg tccacatgtt tctcaagaag
    81361 aaatgatgca atatgtaaat agtgttaaag atgtaaagga agagattgat ttacatgaag
    81421 atgctaaaaa agataatatt tacaaagaag atgaatacaa aaaatatgaa gaagaataag
    81481 taatattttg tataactgaa caaatagtaa tgtcaaatta tttaatatct agttttaata
    81541 tgtaagttgt aacttaactt gaaagaatca gtatcattct ttagatagtt aagtaacaac
    81601 ttacatttta tttttataaa ttttaatagt tctttgtgac tattttgtaa ttttagaaat
    81661 attttagtat ccatggtaat tgtgtataat aaaacttgta tagatagata gtatgaaatt
    81721 aagcagatag tttaaaatta aaatgaaaag aaaggaaata gttatgttaa agttgttgat
    81781 agttgaagat gacagtacta tatcttttgg aataaagtat gctttagaac aagaaggatt
    81841 tagtatagat atatcaaagg atttatctag tggaaaagaa atgatttctt ctaatgaata
    81901 tagcatgata ctgttggatg ttacattgcc agatggaact ggttatgagc tttgtcaata
    81961 tataagagga ttctctcagg ttcctataat attcttgact gcttgtgatg aagaagtaaa
    82021 tattgtaatg ggtctcgata taggtggaga tgattatata acaaaacctt ttagaattag
    82081 agaattaata tccagaataa aagctgtttt aagaagaaaa ggtaatactt cagaagaaaa
    82141 taagaaaata cttaaatttg gagatttaag tatatataca ttagaagcta gagtatataa
    82201 aaatgataaa gaaatatttc tgacatcagt tgaatataaa cttcttttaa ttcttataca
    82261 gaataaaaat actgttttaa gtagaactca aatattggaa aaactttggg atgtaactta
    82321 tgattttgta aacgacaata ctctaactgt ttatataaaa aggcttagag aaaaaatagg
    82381 tgatgattta tgtgaaccaa tctacataga aactgtaagg gggattggtt ataaatggat
    82441 aggaagtgaa aatagtgttt ctatataatc cagaagtgaa gaagttttta agtaagtatg
    82501 ttactttgat gtttattgtt atcataatat ctattggatt tagcataatc aacgtgtcct
    82561 taactaaaga gatggttgta agaaataatc aggctataat aggaacttta tcaagcaagt
    82621 atccaaactt ggaaagtcag atagtagaca taataactca agggaagtct atggagaaca
    82681 tagattatgg tcagaaaata ttaattaagt ataattatga taaatctatt aggataaact
    82741 ctgagcctat tatttctaaa ttagttttag agactatcaa aataaatata atattagtat
    82801 gtataatatt tattttgata tttgtgttgg ttgttagata ttttacgtca atttacaatg
    82861 atttatcaga tatgactaag tatgtttact atagttcaga gggtaagcca tttgatatga
    82921 aaaacaagaa tcaagaaggg cagataggtc ttctaaaaac tgaactctta aagatgacaa
    82981 caattcttaa tgaaaaggtt gaacttttaa aaagagaaaa gatattttta aacaatacaa
    83041 tttccgatat atcacatcaa ttaaaaactc ctatgacttc tttaataatg ttgaatgatt
    83101 tattatataa tgatgtacca tacgaagtaa aaatcgattt tttaaataag ataaaaaatc
    83161 aattaaatag aatggattgg ttgattaaaa gcatgcttaa attatcaaag gtagaagcaa
    83221 aagtgataaa ttttaaaaaa gataaggtaa aatttagtga actcatacat agagcaatgc
    83281 tatctatgaa aatacctatg gagattaaaa atcaaaaact gactatagag ggaaatgata
    83341 atgtatctta tattggtgat attgattggt ccgtggaagc attagtgaat ataatcaaaa
    83401 attgtgtaga acatactcct gaatttggaa atataattat aacctataaa gaaaatccat
    83461 tattttctga actaataata aaagatgagg gtgaaggtat agataaaaaa gatataccac
    83521 atgtatttaa acgattctat agaggaagaa gtagttcaaa agaagatagt gtaggaatag
    83581 gtcttgcaat gtcaaaatct ataatagaaa gccaaaatgg cgatatatat gtaaacagcg
    83641 aaaaaggtaa gggtacagaa tttcatataa tatttcataa aatgtatgat agtgactaat
    83701 ctgtaatatt taattcactt tatagtaata gccaaaacct aatatatgaa gtatagaata
    83761 taaatattgg aggtagttat ggaaatttta agagtagaaa atctaactaa aagttatggt
    83821 aaaaatgaaa caaaagttga tgctataaaa aatgtaagtt tatcagttga aaaaggaacg
    83881 tttatagcaa taacaggtcc aagtggaagt ggtaaaagta ccttattaca tttattagga
    83941 ggagttgaca gaccaactag tggtaaggtt tatataaatg atgttgatat atataattta
    84001 aaaactaagg atttggcgat atttagaaga agaaatatag gtcttatata tcaattttac
    84061 aacttaattc cagtcttaaa tgtgaaggaa aatatattgc ttccagcaga gcttgacaat
    84121 agagatattg atagagaata ttttgatgat ttaatgaaaa cattaggtct aattgataga
    84181 gaaaagcacc ttccaaacca attatcagga ggtcaacaac agagaacctc tataggacgt
    84241 gcattaatta atagaccttc tataatatta gcagatgagc caacaggtaa tttagatagt
    84301 aaaaattcaa aggaaatatt agaattgtta aaattgtcag taaaaaaata caaccagaca
    84361 ctaataatga taactcatga caaaaatatg gcacttcaag ctgatagaat tataagcata
    84421 gaagatggaa tcataaaaag tgatgaggtg atgtagatga atttatatac atcactaact
    84481 attagatact taaaacaaaa taaaagaaga accattgtaa ccataattgg tataatactt
    84541 tcaacagctt taatttgtgg tataggaaat atatttgaaa gttttatgga ttatcaaatg
    84601 agagaaacta taaagaatga tggaagtttc catgttacat tttatgatgt aaatagaaaa
    84661 aatgtggaat atgtaacgaa atcagctgaa atagaaaaac atgcatttac caaacaactt
    84721 ggatattcta aattagaaaa tagtgaaaat gctatattaa gtataaagca atatgataaa
    84781 aatgcaataa acggatataa agtttctata aaagaaggta gatttccagc taaggaagga
    84841 gaaattgttt taagtgaaag tattattaat cttatagatg ataagttaaa aataggagat
    84901 aagataactt taaaagtagg ggatatgttt gactcaagca agaaaaagat tgatagtatg
    84961 acatttcatg aaggtgatta tatagcaaat gaaaaagata gaacttttaa agttgttggt
    85021 ataattgaaa aacctgggtt tgaacgttat aatggaattg caacagctat agcctacttt
    85081 aatcctatga ataattacaa tgatacaatt aatgtatcag tagcagtaag aaatcctaaa
    85141 gatgtgtata agataagtaa taaaataagt aaaaatatat attcaaataa agataaagaa
    85201 gcagtttccg atatgataaa atacaatgaa catttattga ggttacaagg tgctagtaag
    85261 tattcaaata taaatagctc tataaagtct ataattatag cagtaactat tttagtaatc
    85321 atatgtacaa ttgctacagt gtacaattcc tttagtattt ctataaatga acgaaaaaaa
    85381 cagtttggga tattaaattc tataggtgct acatctagtc aaattaaaag attagttttt
    85441 atagaaggta ttataattag tttaattggt ataccaatag gactaatatc tggaacagta
    85501 gctatagacc tattgtttaa aattataaat aagtatttta ctgaatcggt tgttactaag
    85561 atgagtttgc agatagtgta taatccaata ataattattg ttagtataat aatagttttg
    85621 cttacaatct ttatatcaat tctactacct gcaatatcgg cttctaatat ttctcccctt
    85681 aatgtgatta aaaatactgg agagcataaa gtgggcaaaa tcaaaagctc aagacttatt
    85741 aaaatgattt ttaaaactga aggagtactt gcatataaaa atattaggag aaatagaaaa
    85801 aaatttataa taactctttt ttctttaatg gtaagtataa taatatttat atcttttagt
    85861 ggctttacat tacttttact aagaggtgaa gaaattagaa attctcaaag aaaatatgat
    85921 ttgtatttaa ctgcaaagaa cacagctagg tctgtagagg atactataag tgaactagaa
    85981 gatattgatg ggataaaaaa ctttgaattg gcaacaggac aatatgtgtc tataagagta
    86041 agtgaaaata aaataaataa atccaaggaa gatttaatca ggaaatatta tcaaaaatat
    86101 aagattggag atagttatga atatgatttc agtaataatg aattaatttt tccaggagat
    86161 tttgcagtaa aaaacaaaat aaataactta gtacagggct cttttaataa agagagagca
    86221 attgaagaaa atggtgttat attagttaga aaaagtgcat ttgaagaaaa tgggaagaaa
    86281 ggtgtagtag aacttaccaa ctataaagta ggagatacag taaattgtga atatcttgat
    86341 gaaaatgcct taagtaaaaa agtaaaggtc aagattcttg ctataactga tgaagaacgt
    86401 ctaggtcttg gttatcaaaa tatggggtta caatttataa cttatgatga agttgctaaa
    86461 aatttaaatt taaaattaag taaaagcctt atatttattg attcaggagg aagcattaag
    86521 actaagaagg aaatagaagc tttggcaaat aaaaataatt ttaactttta tgatgaaagt
    86581 gcaagcaatg aaagtgaaaa acaagattta aaggttatta aaatatttgt atatggtttt
    86641 atagtagtga tatctttagt gagtgttaca aatattctaa atacagtaag tacaagtata
    86701 aatctaagaa aaagagaact tgcagtaata caatctatag gggttactcc taaaggattt
    86761 aggaaaatga tatatttaga aagttttata tatggtatac tgtcattgtt gtttggaata
    86821 ccaattagta ttggtataat tctaattatg aataaactta tttcaggtgt aattgaattt
    86881 tctccgatta taccgtggac agccatagtt atctgtatag taagtgtttt tataataact
    86941 tttatagcag ggtatatacc aatgagtaaa ttaaataaag aaaatataat agataatata
    87001 agaagagaaa gtatatagat ataaaaataa ttcttaacta tataaaatat tattaaaatc
    87061 atttaagtgg tataaaatat tattatatca cttaaatgat tttttattta tataagaaat
    87121 ctaataataa attactagag gtatttaact atttagaaag aattggtatt atataaagta
    87181 agagaatata taataagaaa gaatatttga ttttattgga aaacaaaaga aaaagaaggt
    87241 gattactatt tctcatataa ctgcgaagaa tatgtataaa agtttagagg aaagaataaa
    87301 caagtttcca caaggtgctc caccatctga tacattatac aaaatactaa atgtactata
    87361 tacagaacaa gaggcgaagt tagttgctca gcttccaata aagcctttca gagtaaaaac
    87421 agcagctaaa atttggagtg taagtgaaag tgaagcatat agagtattgg ataaacttgc
    87481 tagtaaggct ctgatactag atatagaaga taataaaggg aagaaatata taatgcctcc
    87541 tccaatggct ggtttttttg agtttgccat gatgagaacg agacacgata tagaccaaaa
    87601 acttttggca gagctttact atcaatatat gaatgtagaa gaagatttta tcaaagattt
    87661 attttattca acagaaacga agcttggaag agtatacgtt caagaggaag ttttaactaa
    87721 tgataatgag gttagtattt tagattatga aagggctact catataattg atgaatcaac
    87781 tcatataggt ataagtatgt gttactgtag acatagaatg caacatgttg gaaaagcttg
    87841 tgatgctccc atggatatat gtatgacgtt tgacaatgta gcaaattctt taataaataa
    87901 taaatttgca agacgtgtgg ataaaataga atgtaaagaa ctacttcatc aagcatatga
    87961 acataactta gttcaatgtg gagaaaatgt taggaaaggg gttacgttta tatgtaattg
    88021 ctgtggatgt tgctgtgaag caatggtagc agctaaaaga tttggaaatc ttcatccagt
    88081 acagacaaca agttttatac caaatataaa ccatgaaaat tgtgtaaagt gtggtaaatg
    88141 tataactgca tgtccaatag atgcgataag caaggttaag gaagatggta aagaatatat
    88201 aaaaattgat gaggatagat gtctaggttg tggagtttgt gttagaaatt gccataaaaa
    88261 tagcattatg ttattaaaga gagatgaaaa aataataact ccagcaaatt cagtacatag
    88321 agcagttctt atggcaattg aaaaagggca gttacaaaat ttaatttttg ataataatgc
    88381 tctggctagt catagagcta tgggagctat actgtcagct atattaaagc ttgaaccagc
    88441 taaaaagatt ttagccagta aacaattaaa gtcagtatat ttagataaat tgttaagtat
    88501 taatgataaa tagaaactaa cttaaaaaag gcaaagtttt agacttatct atatcttaat
    88561 aaacttatca tttaatattt aaatttaatt tttacacata taaaacttat aacttaaata
    88621 aaaaaaggct atattcaatt aatattactt gaatacagcc ttttttagtt atgttaagct
    88681 atttctttta tttgcttaaa tgagttttca tttccatttc caccaatttg tgttacagat
    88741 ttaaatctca tagttttaaa tagttctttt tgattataat ctagtgagtt tcctactagc
    88801 attacaggag atttagtttt tccagccaaa actccaacag ataatccgtc tattaaatca
    88861 tcttgtttat tcattccatt tttagcaaca tataaattgt ctatcttaga atccttgtaa
    88921 aattctttta ttacttttgc attagtttca tttctagtgc tacctgatat tctctgtgga
    88981 ttttgaagtt tactttctat atttttagaa actgtatatt ctccaccgat tacataagat
    89041 ttatcaatct ttttgttttt aaatacgtta tttatttcag ttatattact attttcatta
    89101 gtaagtatta taggcatatc attttgagct gatacagctc caatgcttac tgcatcggct
    89161 aatccttttt cgccattaac tactgaaatc tttgatatat tgctaatatt gttcaattct
    89221 ttagcaatgt tcatagaagt ttgatatcta tcacttcctg aaattctaga tacagagata
    89281 ttgtttgatt ttatagtatc taaagatttt tcatttatag aagcttctcc accaactaca
    89341 tatacatttt taacttttaa tctctttaat tcagccaaag ttttttcatt tatttgagag
    89401 cttccagtca ataatatagg agcgtttttc ttgtatgcaa atggtgttgc agccaaagca
    89461 tctgcaattg ctgaatcgtt tattaaaact gcattttcag cattttccca acctgcttga
    89521 cttatcttaa tagaagtttc atatctatca gttcctgtaa gtgcacttgc atttacttca
    89581 tcttgatatg taacctcaaa tctagcattt ggacttccta agaaaacaat tacgcctcct
    89641 tttggcaatc taactctatt gttctttgta actaaagaat agtttacagg aacaccttta
    89701 tcatcataaa cagcaaaagc tgaattttga ggaagattaa cttctatttt tttatttgcg
    89761 atatcgtcac caatcttata ccattttgca taaccattgg attctagttc acaagtaaaa
    89821 gatttttctg ctggcaaatt agttatagaa tcttcactaa catacgttag tgttccaaaa
    89881 gataaatact ctgtaccatt ttctttatga agtttaatgt cggataaatc acgacctatt
    89941 acaccaggta tttctataaa agcatttgag ttattctcat ccattatttt agtgttaact
    90001 atataacctg gagtttcatc agaaagacta aaacttgctt ttacagagcc aaacatatag
    90061 ctttgagaag tatatttttc atccactaga tagtaacctt tgccacttct ttttttccac
    90121 acttctttga cactatttga tatattgttg tcatctactt tttgagctac atagtataaa
    90181 cttgctgtct gacctaatcc agggacatca tcataagagc tcatatttaa atatgtgata
    90241 ttattttttt cttttacaaa ttttaaacaa ctattacctt tttcagatac aaatctatct
    90301 tgacctatgt atacgtattt atcttcaggt ccattttcta tataaggaga agatactgtt
    90361 aaagtaccat tatcattaac atctactttt atcatatttg aagaagcata aagaccacta
    90421 ttttctttta aagagcttgg cattttaact tgttgtggct tactaaatgt tttatcaggt
    90481 tttatttctt taattttacc tttttctttt aatgcagata gtaagatttc ttgtccaatt
    90541 atttcattaa gttgactact tccaccagaa gaaagaactg caactgccat attttcatct
    90601 ggaagaacta taagattact gtggaataat aaagaatctc caccttttgt aagagctttt
    90661 aaattatact gattaaatgg ataagtgttg acacaatccc accctaaacc atatccaagt
    90721 atagagtctt ctccttcagg ccatagacca tttaaatatt ctttgttttc catagctttt
    90781 actgaagcag gagaaagaat accatttgaa tttttcataa atgtttgtgc aaatgtacat
    90841 agattttctg cacttgaata taaaccacct gcacctatag cattaaggtt atcttgtgga
    90901 actgcatctt cccaataagg tacgtatgct tttgctagtt ttgaactatc aaagctattt
    90961 tctgtagttt ttgtattttg taagttaagt ggattattta tgtatttatc aagaaaatta
    91021 gtaaatgaca taccagatac tctttctact aaaatttcag ctaaagtaaa tccatcatta
    91081 caataaacgg aaaaagctcc tggtttagct tttaatcttt gtttttgtaa ttcttttaag
    91141 aaattatcat gaccataaga atcattgtct gctaataaaa tagtgttttt aaaactactt
    91201 cccatcaacc ctgatgaatg atttaataac attcttggag tgatttcctt gtatctatca
    91261 tcagccattt taaattcagg tatatacttt acaacaggag tatctaaatt taattttcca
    91321 tcatcaacca acttcataac agctgttgta gtaaacattt tactgataga tgcgatacta
    91381 tacatattat ccttatttaa gtttttgtta tcctgtttgc tgtaaactcc accattacca
    91441 gaaatctcaa ttttgccatt atcaatcaaa gcatattgag cacttacagc accatacttt
    91501 gatagcaaag tttggatttt ctctttagca agagctttag tttttgtgta agattccgcg
    91561 tttttactat aatcatgtaa ttctatatca gaactttgat atttttcgga attatctttt
    91621 gtattatcag caaaagtaat atttggagca gcagtaaata acatactcaa tactaatgta
    91681 ctagataata atttagagag cctttgctta aacatattac attacctctt tcccttttta
    91741 ataatttata attagcataa cattcttaat tattttaatc aacagattat tatcaataaa
    91801 aaaagctttt ataagtatag ctttttatat aacagagaaa aatataaaaa taatatttgt
    91861 tgttgtataa agaataaagg gtataggtaa tatataaata aaatggagga attttagaca
    91921 tatgtataag aatataaata agaagcaact taaagaaatg atgaaaaatg aaaaggatgt
    91981 tttattatta gatgtaagaa ctaaagatga atttaaggaa tataaaatag aaaatgctat
    92041 aaatatatct ttacaagagt taatcaataa tatagatgaa atttacgatt ataaagataa
    92101 gaaagtagta gtttattgca gaagtggtca tagaagtgtt actgcatgta atttgttagc
    92161 tgaagaaggt tttgagcatt tatataattt aaattcagga ataattgatt atatgagtta
    92221 aataatgtaa gttatacatt aaatactatg tatagctctg cttattaagt aggaatatat
    92281 ctaaatattt ataagataaa tttaggaaag aacgaatttt ttcgtttttt tctatgacag
    92341 tttttgtagt aaatattagt ttttaagttg gaaaaaggta gtagcttttt agctactacc
    92401 ttttaatatg aacttagaat attattaaaa aaatatattt aaagacagaa ttaatttttt
    92461 aatgaccagt taaattacta tcgccaaatt tatcattaaa tggttttata actctattta
    92521 taggtccttt tagaagtaca tttaaacaaa tagacagaat cataaatagt aatagaacta
    92581 gtatatcttt agttagattt ggagcatata taccaccaac tgcttccctt gtagcaccta
    92641 ttgcataggt aaatggcatt atagggttta ttctttggaa gaatgtaggt gtaacttgta
    92701 tagggaatgt accaccagaa gaaccaatct gaacgactaa tagtactatt gcaattgctt
    92761 ttcctacatt tccaaataca gaaactaaag aatacactat aaagttaaat accatactag
    92821 taaacataag cagaactatc aataaaattg gatgttttgc tgttactcct aacaataata
    92881 tatctccagt tcctattata aaaccttgga caagagctat acttaaaaaa gtaaggcctc
    92941 ttccaaagta aatttcataa ggtttatagt ttccatgtac agatgtagac aatagtgctg
    93001 aaataagtaa tataccaacc catgtagaaa gaacactata aaatggtgtc attgcagaac
    93061 cataattttc aattggatat aatttctctg ttttcacctc aacaggttct tttaagaaat
    93121 tagactttgt caatatatca ctttcaagca agctgactaa ttttttcata tcttcaccat
    93181 tactaatttt gcttaaagta tcaatcaaat catccaacat tccttttgct aaaggaagtc
    93241 tttctcttat caatgatata ctttcctgtg catttcctga aagttttaga gaagtagtaa
    93301 gtatttcttc aacctttgga agttttgctt ctgccttatc taaaacagta attatatcat
    93361 ttgctacttt tatactgttt gcaaatatac tatttatagg ttttgatatt tttgagtcaa
    93421 aattatttaa aatatttaaa ttaattcttc caataccatt tgatagactt aaaacattat
    93481 tcaaagcact tatagatggt tgttgtccag atataacttt gtttttaata tcatttaatg
    93541 ttgatataga tgaatctatt ttattgctag agtcttcaag attatctatg acatcatcca
    93601 atctattatt tgatgtaagt tggtttaatt tagttaaaaa atccaccaaa gtattattta
    93661 aagattgcaa attagaaagt ttttctgata aattatctat caacttaggt acatcttcac
    93721 tgccactatt tactgcatca attaaattta atgtaagaga agaagcagaa gatgaaaggt
    93781 caaccattaa atttaagtca gacttaataa gaggagaaag ttcgtctaaa ttatcatttg
    93841 tatcctctaa gaattttttt aagtcacttg ataacagttt tgtatcattc agagtttttt
    93901 taattgtagg taaatcagat ttaatatctt taactgtatc agataatttt gaagtagcat
    93961 cagaagctaa atcaacagtc ttatttatat ggtcaaatct cttttgaagg tcaataaggg
    94021 aattttcaac ttttgtcaat tttggaagac tgtgttcaat tcctgcacca actccgtttg
    94081 atataccaag aacgatttca ctaactgttt ttactatagt ctgattaacc tgtagttgta
    94141 ttgtagaagc acctttatct gtaatctttg gtgcaactgc atttattttt tcattaacag
    94201 tatagataat ttcccctttt ttaacatcat ctgtaattaa agatgtcaaa tcttttgtaa
    94261 aattttttgg aatcttaagt gatgcataat aagtaccttt tttaacacct tcaagagccg
    94321 ttttttcatc tacaaactgc caacctaaac tcttgttatc tttgagttgt tcaattaatt
    94381 ggtctcctac attaatcttt tgtcctgcta tttcatttcc tttatcttca tttgttactg
    94441 ctacaagcat attagcagtg cttccataag ggtcccaaga tgcctttata ttgaaccaag
    94501 catacagaga tggtaaaaaa gcaagaccta aaactattac aagtacggca taattgccac
    94561 gtatatcttt taggtcactt ttaaaaattt ctaatatatt ttttaaaccc tttgaaggtc
    94621 ttaaattctt gatattattc cagtttaaaa tttcttttaa actattagtt tttttcaaat
    94681 gtctcacctc ctaaaatatt ttgataaaga aaaaagttag atttataatc aattttaaat
    94741 tatattactt tttacacaaa tagtaaagtt aaaattttgt cttaat
//
LOCUS       DAEOTL010000005        93346 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEOTL010000005 DAEOTL010000000
VERSION     DAEOTL010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 93346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93346
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.005"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..1778
                     /locus_tag="KRH82_000547"
     CDS             <1..1778
                     /locus_tag="KRH82_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8653847.1"
                     /translation="GFSSTGFYVGFLLLIILVVGMYVAYTGLIKRETSKALHAVINFV
                     VVFVLSASFIAYAPDYIKKINEFSSDISTASLDLGTKIMLPNSDSEGKDSVDLIRDSL
                     FSIQVQQPWLLLQFGNSNAEEIGTDRVEALVSASPEDEDGKTREEVVKTEIEDNDNNN
                     LMIPQVVNRLGMVFFLLFFNLGITIFVFLLTGMMLFSQILFIIFAMFLPISFLLSMIP
                     SYESMAKQAIVRVFNTIMTRAGITLIITVAFSISSMFYNISTDYPFFMVAFLQIVCFA
                     GIYMKLGDLMSMFSLNAGDSQSMGRRIFRRPYLFMRHRARRMEHRIARAVSAGGISGG
                     VAGAVAGSAVAGKRSERKNTASKENRGNTTSSMGQRAGSKVGAVLDTKNKVKDKANAV
                     KENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQEQQSRQTGRLEKQEQHKKSIAVK
                     RMELQKAQEARHRKTDGSATTGATRPHERPATASTVPKTSVEKMQEIKRPATAPTSKA
                     SEPVKTNVIKERPLSSGASDMKATQSAQPVHRQNVEKVVSQETRQNYTKDRRTKVQQT
                     QTVQKNQQTTEKNRNIVTKKGQKKK"
     gene            1781..2788
                     /locus_tag="KRH82_000548"
     CDS             1781..2788
                     /locus_tag="KRH82_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBG8653848.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFLGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVHVLLAIIQVESGGTAEDVMQSSESLGLLPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSVGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVAHFDNATAQAIM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNKMYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     E"
     gene            2804..3706
                     /locus_tag="KRH82_000549"
     CDS             2804..3706
                     /locus_tag="KRH82_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653849.1"
                     /translation="MFKKNKKSTENVKEKKVRTVKVGTHKKTVIALWVVLIESVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIEARTQAING
                     YLTKELQDLNVDTIRTDIPTSSTITDVIVWSIEQSGTDTFSATYEVDQQIEEGEQTTA
                     VKATYTVKVHVDDDGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKDSNWKIIG"
     gene            complement(3905..4241)
                     /locus_tag="KRH82_000550"
                     /pseudo
     CDS             complement(3905..4241)
                     /locus_tag="KRH82_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4191..4400
                     /locus_tag="KRH82_000551"
     CDS             4191..4400
                     /locus_tag="KRH82_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653850.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSHPNETDLIELKNAISK"
     gene            4493..7156
                     /gene="mgtA"
                     /locus_tag="KRH82_000552"
     CDS             4493..7156
                     /gene="mgtA"
                     /locus_tag="KRH82_000552"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBG8653851.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARHSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGISTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            7172..7675
                     /locus_tag="KRH82_000553"
     CDS             7172..7675
                     /locus_tag="KRH82_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8653852.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            7813..8490
                     /locus_tag="KRH82_000554"
     CDS             7813..8490
                     /locus_tag="KRH82_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBG8653853.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            8737..9048
                     /locus_tag="KRH82_000555"
     CDS             8737..9048
                     /locus_tag="KRH82_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBG8653854.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            9214..11979
                     /gene="mgtA"
                     /locus_tag="KRH82_000556"
     CDS             9214..11979
                     /gene="mgtA"
                     /locus_tag="KRH82_000556"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBG8653855.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            11992..12159
                     /locus_tag="KRH82_000557"
     CDS             11992..12159
                     /locus_tag="KRH82_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653856.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            13210..13509
                     /locus_tag="KRH82_000558"
     CDS             13210..13509
                     /locus_tag="KRH82_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653857.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFVVGYQIPPFTVSVSAKRGRSLFALATFAGKGVRL"
     gene            13506..13922
                     /locus_tag="KRH82_000559"
     CDS             13506..13922
                     /locus_tag="KRH82_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8653858.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGVMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            13927..14166
                     /locus_tag="KRH82_000560"
     CDS             13927..14166
                     /locus_tag="KRH82_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8653859.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            14485..14628
                     /locus_tag="KRH82_000561"
     CDS             14485..14628
                     /locus_tag="KRH82_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653860.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            14691..16466
                     /locus_tag="KRH82_000562"
     CDS             14691..16466
                     /locus_tag="KRH82_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008689640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBG8653861.1"
                     /translation="MQEVEVIKAKNVLSRQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSQYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKPQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGDGSTIVQT"
     gene            16435..16743
                     /locus_tag="KRH82_000563"
     CDS             16435..16743
                     /locus_tag="KRH82_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009537682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase"
                     /protein_id="HBG8653862.1"
                     /translation="METVALLSKLDVDKHIDVEIKLDEFDLTSAESKATYAQIKEYVL
                     EKFGLKVSTLYIAQIKKKCGIEMREHYNKSKKDNQAIPQCTPEKEEAIMDALRHFKMI
                     "
     gene            16762..17043
                     /locus_tag="KRH82_000564"
     CDS             16762..17043
                     /locus_tag="KRH82_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653863.1"
                     /translation="MRWILKIILFPISLLLSILTAFLSFLLGIGTAILYLLMMFCIFG
                     AIASFLQKEVTIGIEALIIGFLVSPYGMPMVGATVIAVLQGVNERIRLV"
     gene            17184..18107
                     /locus_tag="KRH82_000565"
     CDS             17184..18107
                     /locus_tag="KRH82_000565"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653864.1"
                     /translation="MSSYNFNYIIPDNFNRRTFQYLQQKNSNLATTFARCTYEYEDVG
                     LAYYAGLKTGDNWNKHALDFTIEGNQNDIEILQQLNSDLKDAIDKALKPSVSGLIIRH
                     IYYLPSEESTLDLPQSNVARLNADISTAEGVLKDLIQVSERLCSNSLYSDISLENSIN
                     DYFRDALSFMGYNEVKDQTRHGVSISEKDAGEVDLLLTKSGKEIAIFEGLKLDSVNSK
                     YIDEHIKKAIDNYNALGTATFVVAYVNVVNYDRFWEKYYEHISNYAHNMECKSAMKEL
                     THPNAATRIAYEVLSKDGYDFPVYFMTIKIA"
     gene            18253..19269
                     /locus_tag="KRH82_000566"
     CDS             18253..19269
                     /locus_tag="KRH82_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653865.1"
                     /translation="MSMYLFDEQPIVANKTLAREIGLNEALILQQINYWIEINKKSGK
                     NYHDGKYWTYNSIRAWQENDFDYMSFDTVKRTFSKLEKAGYLLVGNYNKDPRDKTKWY
                     TINNDKLEELYVDMELKKQKIQTEALKKSMPNTLGQNAPMDKGKINQCNNADCTNAQV
                     QNALMQRDNLHQPLPENTTNNTTNNSADISIHPSIKEKNQLFSENMKGRRIDISYKNI
                     YQNCLEELRHQTGYYEHMSIGNKIVAEEFDEILKILADVMVLDDESFITINQTKISVQ
                     VVKERFRELNSGHLEYLVGVLRENEYKIRNIRAFVLTAAYNAPTGIDAYYSALVSYDM
                     RGGY"
     gene            19271..19756
                     /locus_tag="KRH82_000567"
     CDS             19271..19756
                     /locus_tag="KRH82_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBG8653866.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILDLLKKLMKEAEKLGGLEK
                     LVNVNGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALSESEKKAEMKESIHKNIEKFKEIAKNSISKDKIKNKQKEQS
                     L"
     gene            19753..21534
                     /locus_tag="KRH82_000568"
     CDS             19753..21534
                     /locus_tag="KRH82_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBG8653867.1"
                     /translation="MIDKILKEIKGLFKVQDKAKFLKQNIPYLAFFYVGNIFSHHVRA
                     YTGGDVIDKIFQGILELNIMSFLPSLHPTDILIGIGVAALIKFIVYTKGKNAKKFRQG
                     KEYGSARWGTRKDIEPYMDEKFQNNILLTQTERLTMNGRPANPKYARNKNVLVIGGSG
                     SGKTRFYVKPNLMQMHSSYCVTDPKGTIVLECGKMLEDNGYEIKILNTINFKKSMKYN
                     PFAYLRSEKDILKLVQTIIANTKGEGEKAGEDFWIKAEKLYYTALIGYIFYEAPREEK
                     NFATLLDMIDASEVREDDETYMNPIDRLFEALEKREPTHFAVKQYKKYKLAAGKTAKS
                     ILISCGARLAPFDIQELRDLMKEDELELDTLGDRKAALFVIISDTDDTFNFVVSIMYS
                     QLFNLLCDKADDVYGGRLSVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQA
                     QSQLKAIYKDNADTIVGNCDSTLFLGGKEKTTLKELSETLGKETIDLYNTSETRSNQK
                     SFGLNYQKTGKELMSQDEITVMDGGKCIFQLRGVRPFLSDKYDITKHKNYKLLEDYDK
                     RNLFDIESYIKRKGKVKMNRHTVITRL"
     gene            21698..22564
                     /locus_tag="KRH82_000569"
     CDS             21698..22564
                     /locus_tag="KRH82_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009731661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8653868.1"
                     /translation="MNIIKSFNSTIDYLETVLDDEIDEKKVTRISGYSYSMFSRLFSI
                     LTEMTLSEYLRSRRLTEAAIILRDTDEKIIDVAFKFGYESSDSFGTAFKNFHGFTPSE
                     VRNGKPFKLVSRVQLALSVRGGRSMNIRIQKKKAFTVAGVNQQNINSSICASLWQKLF
                     SKVSHEEMLNLGTGEAVGVCHDILSLDNHDVLDSNTINYMAGYIVTDVDKARSMGLDI
                     LEIGETEYAVVELTGSVPECIHNGWKYAMEVFFPEHGYVHSGKPDFEYYYEGDMYSKD
                     YKMELWIPVCKS"
     gene            22778..23089
                     /locus_tag="KRH82_000570"
     CDS             22778..23089
                     /locus_tag="KRH82_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBG8653869.1"
                     /translation="MKQEMININANLLAEPTFSKFEKEGEKVEVANFTLVKKYGKGKE
                     YINCAAYGEKAEIAKAFEKGDLIHIFGYFKKREKEGKTYKNFVVKSYNKIEKKEKNEE
                     E"
     gene            23093..23308
                     /locus_tag="KRH82_000571"
     CDS             23093..23308
                     /locus_tag="KRH82_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HBG8653870.1"
                     /translation="MEFFGQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            23328..24191
                     /locus_tag="KRH82_000572"
     CDS             23328..24191
                     /locus_tag="KRH82_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653871.1"
                     /translation="MFGIFDKIEEFFKELLLGGIQANLESMFLDINDKVGAVATDVGK
                     TPMGWNGQVFSFIKSINDSVIIPIAGLIITAVLCIELINMVMQKNNMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFEFSMAVFDVAQHMVNKAAGVINTSATVSGDQIVAMMDTLKEKG
                     LGELVMILFETSLIKVAIQVISVVIMLVVYGRMFEIYVYSSVSAIPFATMGNKEWGQI
                     GTNYIKGLFALGLQGLFLMVCLGIYAVLVKTIQITDIHTSTMTILGYAVLLGLMMLKS
                     GTLAKSVLNAH"
     gene            24211..24474
                     /locus_tag="KRH82_000573"
     CDS             24211..24474
                     /locus_tag="KRH82_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653872.1"
                     /translation="MNKRKTVFTAVVIGAGIMAVIDRIRFHNKVDELEERTEDIGRCH
                     NDFCLMQQRYNRSTDEQIVSIQEEIGSVYEHIEELSKEKEDGR"
     gene            24478..24867
                     /locus_tag="KRH82_000574"
     CDS             24478..24867
                     /locus_tag="KRH82_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HBG8653873.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLIGIPIYLFMR
                     KVVPNDIAVIFLIVSTLPIFFITLFEKDGLTFEKYFKYIYLHKFYQPQKRVRKEVYLE
                     RQKKDSAAKVRTKQKEVKKSKTGLKAK"
     gene            24779..27208
                     /locus_tag="KRH82_000575"
     CDS             24779..27208
                     /locus_tag="KRH82_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8653874.1"
                     /translation="MKDKRKIQQLKLEQNKKKLRSQRQDLKQNKGKSKKDKGGLLDLI
                     FRKEPKRYTVEDTIPYLRLLKSGICQIDEKHFNKSIAFEDINYQLALEEDRDLIFNQF
                     ANFLNSFDPSISIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIAKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERMEIDILSSLKSMGVRAESLNGEERLKILHD
                     VLNPNKTFEFSYKDLKKKESTKTYIAPDEFNFTPSRYFKFGKFIGAASHFQILASELS
                     DRMLAEFLDIDDNINISFHIKAIEQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVTIIFMNFARTIQKLDNTISQISSIANKH
                     NCKLKRLDHSQEQGLISVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSVNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILTTDDDVIICDPEG
                     EYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYEKYFENPLPENMPILQNLYDMLKGQEEKVGKKLATEMEIY
                     VTGSLNVFNHQSNVDLNKQLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISQPQLKYVTNSNAGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            27213..29312
                     /locus_tag="KRH82_000576"
     CDS             27213..29312
                     /locus_tag="KRH82_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8653875.1"
                     /translation="MGKKLKRDFKERQRARIEKETLQSSGSIESEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKTSKIISDSEPVRGISKRNTRYRSSETGSVSREEIGKADYATEV
                     NDGIIDRYDNDFRGSEYFESTYDVEDNLHHKAEDTKGFLKNQKAQKKNYKRKNYSDKL
                     YTRKKDTEAKAEKADNKQGGKEAILDREKKNKLSKEQETIFKNKASKVSALSGLAKGS
                     ETVRDYLSHGSDENQGVEAGEKTADTSSKLIHGIKNYSDKKRAQKGYDLINKDYKIRK
                     RKSKLEFRDVKEELKKTEEYQKANNFKRFQKRKQMKDSIKRQNKSRLRDRIKEGLIGS
                     LKGSKEIILRKTKGLMIIFIGLIILGTFFINFAGTGMTGFMNSTSIVLTTSYLSKPNV
                     LTEINQQFSSMEQGLQDELESVEENHPGYDEYIVNKEEDIGHNTHELLSYITSRCGEV
                     KNISEVNRILDELFKSMYRVDYKEEIEIRYKTVAETYTDEDGNEYTESHEEPYEYKKL
                     IVTLYKREMDSVVREVFQNYPDNVKHYEALLASLGNMSDFFGSGSNDYSEIINNPNFG
                     NPGIAFNEETVKRLFSEAERHIGKRYVFGANGPSNFDCSSFVCWSFTRSGIKNMPRTT
                     AWRIYTDYCNPVSTGEAKAGDIIFFKNTYNSGSPISHVGIYAGNGMMIHAGDPIQYTS
                     INSPYWREHFYGFGRPR"
     gene            29324..29557
                     /locus_tag="KRH82_000577"
     CDS             29324..29557
                     /locus_tag="KRH82_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8653876.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIAI
                     CRKNNITIYDLMAKVNREKSEMKKENGNEKNEE"
     gene            29538..31106
                     /locus_tag="KRH82_000578"
     CDS             29538..31106
                     /locus_tag="KRH82_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HBG8653877.1"
                     /translation="MKKMKNKKAAGVILGAVLLIVGVVISLFAGSKIVFAQGGLFTTL
                     VNPIEAVAQIEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPIIPDDMKFIDDFL
                     FYEIKGDGKDEIIRKVAKVEVKDKETQTENESSKSEQSSQSNASKKENKGTQTELSKD
                     NISKMEKESKELQEKLDKLNQEIKDKDKLSDKQKDKIKDLEDKIDKLKGKLEKSKADK
                     DLSTDMKKEMDKLTDKIKELEKKANEVGRAPVTHNPTVAPINPISGIKQGTGNVSPQA
                     SINSSGKGSASQESKGANTKNIDSDKSKEKEKEVRYPNKLTPKQPANNGSQDSSLDGS
                     SKNVNTNKGIASAPSKARGAVTENKDNANKDYPIHHNDSKDNKEMDKYSADARQFVTF
                     TTKNGKTFHLIINHDENSENVMLLTEVSEDDLLNMVEKKAPEKEVVKEEPQKEELKPV
                     KKEESSNTGIYLILILVVAGALGAGYYFKVIKKKEDKELEGFEEEDDDFFSEAEESEN
                     ESDETEDKEDDEVE"
     gene            31203..32909
                     /locus_tag="KRH82_000579"
                     /pseudo
     CDS             31203..32909
                     /locus_tag="KRH82_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
     gene            32994..33179
                     /locus_tag="KRH82_000580"
     CDS             32994..33179
                     /locus_tag="KRH82_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBG8653878.1"
                     /translation="MSEAFMNNAKVMSKGQVTIPKKIREILEIENGDYVTFVVTEGKI
                     QIVNSKTFIEKNIQGRK"
     gene            33213..34259
                     /locus_tag="KRH82_000581"
     CDS             33213..34259
                     /locus_tag="KRH82_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HBG8653879.1"
                     /translation="MNKEKNSLQNINIEKNNNSFEEIVMIVENAKDRAYRRVNEELIL
                     MYQEVGKYISEKTKEASYGSGFVDNVAEFFSINYPDLKGFNRRGLYRMKQFYELYKDD
                     GKVSTLLTQLSWSNHLKIMSGAKSREEREFYINLAIKENLTHRELVRQMDSGYYERCM
                     LSNEGNMPAIQRAKQETHNLFMDSYVLEFLDAPKIGNERDFQKSILENLKNFVLEIGK
                     DFSFIGNEYRVQVGNHDYYIDLLFYHRGLSCLVAFELKIGEFKPEYVGKMNLYLEALD
                     REVKKQAENPSVGVILCASKDDEVVEFALSRSLSPTMVSEYRLKLIDKELLQRKLKEY
                     TGIAEQEIERYDEK"
     gene            34369..35175
                     /locus_tag="KRH82_000582"
                     /pseudo
     CDS             34369..35175
                     /locus_tag="KRH82_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861366.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            35289..44276
                     /locus_tag="KRH82_000583"
                     /pseudo
     CDS             35289..44276
                     /locus_tag="KRH82_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906446.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            44331..44990
                     /locus_tag="KRH82_000584"
     CDS             44331..44990
                     /locus_tag="KRH82_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBG8653880.1"
                     /translation="MNYKEIRNTLEQMANESHEDFAKALISFEKGINDKEALDKLYQE
                     YMENDSMSLLNDEFDYLIEELRENGQIKDTAAIEKEDNDLVNIVGNIVGEVDVVEREN
                     KNGEVFKVVNFSVASKDDDGSKTYTNCSAYGDKVEIPKDFKQGDFVKLFGQLRTSIDD
                     NGKEYSNVRILSSKLLKAKEQMKNQEEKKESVLGAIKKYKAEEKAKPTEKKEALKETE
                     R"
     gene            45120..45338
                     /locus_tag="KRH82_000585"
     CDS             45120..45338
                     /locus_tag="KRH82_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653881.1"
                     /translation="MKFNYNGLWKVLIDKNMKKKDLIDRTGISPTTISKMVRGEAVSL
                     SVIGKICEELGTDIGDLIHIEKGIEEDK"
     gene            45339..47516
                     /locus_tag="KRH82_000586"
     CDS             45339..47516
                     /locus_tag="KRH82_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBG8653882.1"
                     /translation="MQSTYNALEYNKLISFIWSVADDCLRDVYVRGKYRDVILPMTVI
                     RRFDSIIEPEKANIMKVKEMAEKQGWDVAKTLDTAVGLPFYNTSNFCLKDLKHETNRQ
                     NLKKNFEEYLNGFSENVKEILQKFDFNNQLTKMTDAGILGSVIEKFTSSELNLSPYDE
                     KNSNGEIIKKGLDNHAMGTLFEEIIRKFNEENNEEAGEHFTPRDVIELMADITMYPIM
                     DKIKDGTYSIYDGACGTLGMGTVAEERLKDFAKENGKEVSIHLIGQEVNPETYAISKA
                     DLLIKGGDTDSNNVHYGSTLSEDKTSGQHFDFMLSNPPYGKSWKMDLAILGIGEDKDL
                     KKNIIDKRFVRNYKEQNDFRMIPDVSDGQLLFLLNNISKMKETELGSRIVEVHNGSAL
                     FTGDAGNGASNARRFMIEEDLIEAIIQLPENMFYNTGITTYIWVLSNRKEERRKGKIQ
                     LINANGIKTSLRKNMGKKNCEFSEADRRFILNEYLKFEENEYSKIFSNEEFGYFKVTV
                     ERPLRQAVLCNYENINEVEKELEKIGATTGKIDKKLIAESFVKGTAGSIKELEKKENI
                     KAYLEVLREMESSEKYLDYEAFEKAFNKNLKNKNIKGASFSKLVSTGLLANMIIRDEE
                     AEVQTDSKGNLIVDPELRDTESIPMTFVGGIDEFIRQEVLPYHEDAFVDESKTQIGYE
                     INFTKYFYKAKKLENVEDIVCRIKELEKRSDGMMETVLEGLYE"
     gene            47509..48870
                     /locus_tag="KRH82_000587"
     CDS             47509..48870
                     /locus_tag="KRH82_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBG8653883.1"
                     /translation="MNKYERYRDTGLIWINKVPKKWNLQKINAVFDERREKVSDKDYE
                     ALSVTKNGIFKQLDNVAKTIDGDNRKKVKINDFVINSRSDRKGSSGLSRFDGSVSLIN
                     TVLKIKKEYPRYMHYLLKSVPFQEEFYRNGKGIVADLWSTNFQSMKSIILPIPPIEEQ
                     VQIANYLDWKINEINRLIQIEKEKIKELETLRFNAISEFVLRGIGTQNYKKSSINWLD
                     EIPSHWNEVSIRWCVNIIRGNSTFTKDDLQNRGKYVGLQYGKVYKTEIIDSEFDFYVS
                     DKFYKPAQVVNRNDIIIVSTSETVEDLGHTSFYDRDDIGLIGGEQILLKPSNNINSKY
                     LFYLSKIFRMQLQLCATGIKVYRFKISDLKQIYVPLPPMKEQEKIVSNIELKLEQIDE
                     RVKNNYAFIKELELLKQSLISEVVTGKIDVRNIDISEYEKVTIIEDEIEEFDEVGGEE
                     DGN"
     gene            48860..51778
                     /locus_tag="KRH82_000588"
     CDS             48860..51778
                     /locus_tag="KRH82_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004027190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBG8653884.1"
                     /translation="MGIRDTKMEAELENNIIEYLTREQKYGAYQYITPDEMKLSYNRK
                     YAFDEIRLLTFIKESQPGEFDILRLDTEDGKDKFFKQLDVSIKQKGIVAVLKNGIKCY
                     PSSGTIIFYHALDPKRPSSYDEFRENIFTVTNQLTYSDKNRGLELDLAIFVNGLPIVT
                     MELKSRASSNGWTYKDAEEQYKNDRDPKETIFSFKRCIAHLAVDENFISFTTRLDGKN
                     TRFMPFNKGTIDGGSGNPINPDGTMTDYLWKNFLDKEILTSLIRDFAYISVDKVKKSE
                     TLIFPRYHQYRVVTRLVDDVQKNGVGNRYLIQHSAGSGKSNSITWLAYRLVEVDYNNQ
                     KAFDSVIVVTDRLNLDKQINDNIRKFIDEKSVVGHANSSTDLKNLLVDGKKIIITTVQ
                     KFPYLLEKIGTDLKGKNFAIIIDEAHSSQSGRAAASLNMAVSGSLSNDDEFEIEDKLN
                     EFIEARKMPENASFFAFTATPKAKTIQMFGNVFDLYSMKQAIEEGFILDVLKNYTHYE
                     NYYKIYKTIEDNPNFDKKKAQKKIRNFVEGQEFPIREKAEVMVNHFLTNTVNKINGKA
                     KAMIITQSILRAIEYYYIVSELLNNSNTGYEALVAFSGEKEYKGKVVTEASLNGFSDK
                     ETPEKFKQDKYKFLIVADKYQTGYDEPLLHTMYVDKVLNDVKAVQTLSRLNRSAKYKI
                     DTCVIDFANEPEHILEAFQPYYKETKLEGETDPNKLNNLLSMLDSKYIYEEDEVDRLV
                     DLFLKNSPRSFIDSIVDKSVERYKVLSEEEQVEFKSGVKSFIRTYNFLASILPIGQVD
                     WEKKVIFFEQLIHRLPTPEGEDLSEGILESVDLESYRLEKKNTIDIILEDEDGIVEGL
                     GISAGKKNEVELDSLENIVSTFNDIFGNIDWQDKDNVARQIKELPEMVMKNEKFKNAL
                     KNSDIENIKREYHSALKEVFRIIMVDNMELFGQWTNNSNFSKWLNDTIFDEIMKKNKR
                     "
     gene            51793..53067
                     /locus_tag="KRH82_000589"
     CDS             51793..53067
                     /locus_tag="KRH82_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653885.1"
                     /translation="MGSISGVTRRDIIDLFKNGITEDNWLTEETIYYPYYGRFDIVDF
                     LKRLYKLDTWKSGDSRLKNAEQEITMHTRNGDYPDDWIFADERFHLLDGEDSVLLGFL
                     CEVFHPEVRDENKEWKKYLERINSLLREDGYELIASSRLSGRDVFTWRVYIKKPDMYI
                     PFSERNKSLIVGRKINFKLPNAVRHQLFKVMDEYDEIFYLTDETNWNYTKYSSDYVLE
                     DINKFYVPKHYVDSNLAEIKKFKDFQEGTSPFVIFDVIESFNRHTTNSEGFENEINSI
                     FNLNNINVELRRGEIHSSTNKTLSLDPSVKINEIGIEELIRAAEDLYRKGKYSYAVEK
                     IWDAFERIKTYYYPELDKKKSANKIIDELSNGNDSIKSMFQAEFKYLTDIGNSYRIRH
                     HEKNKIDITEDLHYEYFYKRCLALISVLVKKI"
     gene            53085..55622
                     /locus_tag="KRH82_000590"
     CDS             53085..55622
                     /locus_tag="KRH82_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004027226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBG8653886.1"
                     /translation="MVDFKKKVALKSKAKVTNPIDLYNTLDRKSIAGPLRPVQEYVLN
                     EWYENRRNERDLIVKLHTGEGKTLIGLLILQSSINIGEGPCIYVCPNIYLVRQVCAEA
                     NKFGIPFCEIEQNNVLPNEFLSGEKILITHAHKIFNGKSIFGIGNKCVNAGTIILDDS
                     HACIDVLKDAFTITIGKKEKENVYNKILTLFSEDLIEQGEGSFLDIKSGEYETFMTVP
                     YWAWINKKSEILKILSDESASDEIKFAWPLMKDKIIEYSCFISGNKIEITPYNVSVEQ
                     FRTFSSAKRRILMSATTQEDIFFVKGLDFSTNAVANPIKYPKSRWSGEKMVLMPSLID
                     EECDRDLVATQFAALTNAPFGVVAIVPNTKRAVYYENIGANFPKNNKELFEVIDDLRK
                     GKFSNTVVINNRYDGIDLPDESCRVLVIDSLPYLNSYFDKYEEKCCPNSEIINKKIAQ
                     KIEQGIGRAVRGEKDYCAIIVIGSDIEKFMRGILTRKYFSSQTQKQIEIGFEVAKMAK
                     EEILQDDPSMKQIFSLIKQILNRDEGWKEYYASEMNEIEDGVLDTSIYERYAAETKLE
                     KLFSDGEYEKASEETQKFIDKFIHDDLERGWYLEQKARYTFMYSQEESAHLQKVAFQK
                     NSQLLKPNSGIIYDKVSFLNENRLIRFRKYISKFNDFDEFSLHLNEVLNNFSFGIDAD
                     KFESALKSIGEMLGYISQRPDQEIRKGPDNLWCASNKKYAIFECKSEVDENRGAIKKS
                     EAGQFNNHCGWFKTEYDEYVDVLRVIVIPTKKLARDADFTDEVFVMRKNGVKKLKDNI
                     KNFMKEIKKYEIESITDTKLQKYFDMYNLNIDNLIGNYVEEIYHLEK"
     gene            complement(55639..56970)
                     /locus_tag="KRH82_000591"
     CDS             complement(55639..56970)
                     /locus_tag="KRH82_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBG8653887.1"
                     /translation="MAITKIHPIKSTLNLAIAYITNEEKTDEKILISTNNCFTSTAHT
                     QFLKTREDNNVKGTVLARHLIQSFLPGEATPEMAHKVGMELCKKILKDQYEFVLTTHI
                     DKGHIHNHIIFNNVNMITGKCYQSNKRSYHKIRYQSDKLCKENKLSVIDEFYETYKKK
                     YKTNGKSWYENEQFKKGTSWKSRLQFDIDRTIKQSKDWDEFLKKMAAIDYEIKYGKHI
                     AFKHKDKERFTRAKTIGDDYTEDKLKERITKNANQKTYTVKKRVGNIIDIANNEKVKS
                     SKGYEYWATKHNLQVATNMVVLMREKGFKSISQLDDFIKESADKRQNLQDEIKILDSK
                     ISALSSTMEQVHTVKIYRQIYQGYKKEPSDKGFFDEHKAEITLYQNALSDLKKSYSKL
                     PNSKDILAALDSLHEKKNTLMQEYSSTKSDMKELYQIRKNYEKYMGKEMER"
     gene            complement(56971..57330)
                     /gene="mobC"
                     /locus_tag="KRH82_000592"
     CDS             complement(56971..57330)
                     /gene="mobC"
                     /locus_tag="KRH82_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBG8653888.1"
                     /translation="MANRVRNVQLKINLTEEEKAFFEKKMKMAKCKTMSLFLRKLVSE
                     SDIYVVDLQPFREIQGLLFRYASSVNQIAKRVNSTGVIYSDDIKDMKSQIEGLSKEIW
                     QIHSLLLNRTTDKGDEV"
     gene            57664..58821
                     /locus_tag="KRH82_000593"
     CDS             57664..58821
                     /locus_tag="KRH82_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBG8653889.1"
                     /translation="MKKIVSRGACLLLTLCLSLSTVGCKKSNESNKIKEGQSISSEEA
                     GMSTNEKDKNETFKPSDYTLKTKKEYVYEYLGLKFKLSDKFKKYMDDKKIAMLDDQSP
                     IDKELKYAFLTFNKMTEEQKNAVINKKGDGYEKWKNGLKRIGTIGIFEKNTSEEKISK
                     ITKCDTHTKIGVSSDGKYDCYLSTNSGSESNLLDEFKKTEIQIIDKKERPKNGFVLSE
                     KTDLENTEAFNKESVKDLRKLSTKDINGKDFTSKDFDKYDLTMVNVFATWCTACVKEI
                     PDLVEVQNEMKSKGVNMVGVVTDTVDDNGENKEAIEKSKLIQKKTKASYPFLMPDKTN
                     FNGRLNGIQAMPETFFVDRNGNIVGDTYSGAKSAKEWKQVIEKELAKIKNK"
     gene            58843..58995
                     /locus_tag="KRH82_000594"
     CDS             58843..58995
                     /locus_tag="KRH82_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653890.1"
                     /translation="MVNKFLKSRTLSLVIVFISMAMTYYGHSHGEARVVLEKAIRICM
                     ECVGIG"
     gene            58988..59878
                     /locus_tag="KRH82_000595"
     CDS             58988..59878
                     /locus_tag="KRH82_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8653891.1"
                     /translation="MDRIKKIINGSTKKDKYKIRDRFRHLFQSVWFLVTNSYFEGFKT
                     GKIYGGDLKEVCVPGMNCYSCPGAKGSCPIGSLQAVIGNSNYKFSYYIVGFMFLIGAL
                     IGRFVCGWLCPFGLIQDLLHKIPFFKKIETFKLDKHLRKLKYIILIVFVIILPLFLVD
                     ILGQGSPYFCKLICPVGMLEGGIPLVLLNKSMRGAIGFLYYWKGVILILTLLLSIVIY
                     RPFCKYVCPLGAIYSVFNPISVFRYRLDEEKCISCGRCKKVCQMNIDPVENCNHLECI
                     RCGRCKNACPVDAISCGIKK"
     gene            59932..61209
                     /locus_tag="KRH82_000596"
     CDS             59932..61209
                     /locus_tag="KRH82_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653892.1"
                     /translation="MIKNAIAYITRKKNRTFIIFVILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDKFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNKSENNKIANKILMYSGSLESTDLALNKLKELKIDESKYSIEKDSNVFEES
                     LESVSGIKHIIKIMTYSIMLGGMVVLLLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMLNITTLGE
                     SYLILISIIVLSVVFASSLILIKKPKEILSKIS"
     gene            61219..61875
                     /locus_tag="KRH82_000597"
     CDS             61219..61875
                     /locus_tag="KRH82_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8653893.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLFAGLDKPQTGKILFKNEDIEKKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADAADIILELSGKKLKKVNKMNLEVE
                     "
     gene            61875..63251
                     /locus_tag="KRH82_000598"
     CDS             61875..63251
                     /locus_tag="KRH82_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8653894.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFFMEINRQVNPGTPRGGGNVKGEDIKKISQTDSVDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSSKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     VQELYENTLITDVHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFVGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTAGKLGNNILNKVTGDIAKQIARQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFIIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            63349..64002
                     /locus_tag="KRH82_000599"
     CDS             63349..64002
                     /locus_tag="KRH82_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8653895.1"
                     /translation="MKILIVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSAI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKVRIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELDVLKCLLD
                     NDGQVLTRMQIIDYVWKDSEEIPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLEIK"
     gene            64007..65329
                     /locus_tag="KRH82_000600"
     CDS             64007..65329
                     /locus_tag="KRH82_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8653896.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLVFFIFPKTYLETRKEE
                     IHNKANEISSNMNGKEIKYIEQTLDLYSKSSEIKAFIKEKKNNNNEIQIKDNIDANLE
                     SNSNSLIIEEREIKLNDGKKTYLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIIS
                     LIYAKLIKNNIQEIKIVTDKMMKLDKKMRLKVSSNDEVGELKQQINDLYSTLLRTIDD
                     LEFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECI
                     EIVDSLTKNISQILSVHSIENLNNDEEYLKINDTIEDILKKYEILANQKKITVNNYIL
                     DENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKI
                     FDVKFDLNKENSNGLGLYIVSNILNNYNIEYKALQDEEFFIFKIKIFS"
     gene            65853..66263
                     /locus_tag="KRH82_000601"
     CDS             65853..66263
                     /locus_tag="KRH82_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004634151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8653897.1"
                     /translation="MAKEYYLYIRGQKVKVSEDIYIVYWREKEHEKYLEQVDRKNHLL
                     FFSALDHDGHFTDNIVDESVDVEKIVETQMMIEAVRSAITRLNAEERDIIERLYFNDE
                     TVRSVAKLKSITHPALIKRRNKILEKLKKFIEEL"
     gene            66752..66904
                     /locus_tag="KRH82_000602"
     CDS             66752..66904
                     /locus_tag="KRH82_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653898.1"
                     /translation="MDNDWNGLADLIANLITKYAGVLDLENLPNPTPVKNTEDKNKFD
                     IAKSTD"
     gene            67005..68681
                     /locus_tag="KRH82_000603"
     CDS             67005..68681
                     /locus_tag="KRH82_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBG8653899.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIDGYSLEAQKSRMKAFALYNDYEIV
                     GEYEDAGKSGKSIEGRVQFTRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDFGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRVQTMEGRIQKAKEGKWNG
                     GFAPYGYQLIDGKLIINEEEAIAIRTIFDQYVNTSIGANGLSKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYRQVEQDDYLVAEGIHEAI
                     IPDELWQAAQVKLKAQAKKYEHVNKGKNMRTHLLSGIVKCPICGAGMFGNKSIKYKKD
                     GTKYKDFYYYGCKHRLMNRGHKCTYNKQIREELLDDAVAEVIIKLVSNPKFASMMQEK
                     INMKVDTSAIENEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKNDLDDRLYR
                     MYDKIEELESQLIEAKAKKETIEVEKLTGDNIYKVLIYFDKLYKVMNDVERRQLIEAL
                     ISEIQIYEEKQPNGQWLKSITFKLPIIDKDLNISLDNDKQVETVAKIIKQ"
     gene            complement(69159..69797)
                     /locus_tag="KRH82_000604"
     CDS             complement(69159..69797)
                     /locus_tag="KRH82_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653900.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIDVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(70207..70383)
                     /locus_tag="KRH82_000605"
     CDS             complement(70207..70383)
                     /locus_tag="KRH82_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653901.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(70437..70533)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            71329..71730
                     /locus_tag="KRH82_000606"
     CDS             71329..71730
                     /locus_tag="KRH82_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBG8653902.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     gene            71727..72794
                     /gene="rsgA"
                     /locus_tag="KRH82_000607"
     CDS             71727..72794
                     /gene="rsgA"
                     /locus_tag="KRH82_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBG8653903.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVHRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            73330..74028
                     /locus_tag="KRH82_000608"
     CDS             73330..74028
                     /locus_tag="KRH82_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653904.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINENMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYAKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            74206..75096
                     /locus_tag="KRH82_000609"
     CDS             74206..75096
                     /locus_tag="KRH82_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653905.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMNSLFILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(75497..76453)
                     /locus_tag="KRH82_000610"
     CDS             complement(75497..76453)
                     /locus_tag="KRH82_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8653906.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            77156..78151
                     /locus_tag="KRH82_000611"
     CDS             77156..78151
                     /locus_tag="KRH82_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8653907.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIVPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKISVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            78129..78992
                     /locus_tag="KRH82_000612"
     CDS             78129..78992
                     /locus_tag="KRH82_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBG8653908.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            78989..79783
                     /locus_tag="KRH82_000613"
     CDS             78989..79783
                     /locus_tag="KRH82_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBG8653909.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            80068..81447
                     /locus_tag="KRH82_000614"
     CDS             80068..81447
                     /locus_tag="KRH82_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8653910.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTISGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVETFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            81895..82608
                     /locus_tag="KRH82_000615"
     CDS             81895..82608
                     /locus_tag="KRH82_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8653911.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAKNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(82880..84418)
                     /locus_tag="KRH82_000616"
     CDS             complement(82880..84418)
                     /locus_tag="KRH82_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBG8653912.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENGQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            85300..85755
                     /locus_tag="KRH82_000617"
     CDS             85300..85755
                     /locus_tag="KRH82_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBG8653913.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSNLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            85804..86388
                     /locus_tag="KRH82_000618"
     CDS             85804..86388
                     /locus_tag="KRH82_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBG8653914.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(86393..86716)
                     /locus_tag="KRH82_000619"
     CDS             complement(86393..86716)
                     /locus_tag="KRH82_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653915.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            86868..87386
                     /locus_tag="KRH82_000620"
     CDS             86868..87386
                     /locus_tag="KRH82_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8653916.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(87562..88230)
                     /locus_tag="KRH82_000621"
     CDS             complement(87562..88230)
                     /locus_tag="KRH82_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653917.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            88345..89760
                     /locus_tag="KRH82_000622"
     CDS             88345..89760
                     /locus_tag="KRH82_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8653918.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKEFSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            89983..90441
                     /locus_tag="KRH82_000623"
     CDS             89983..90441
                     /locus_tag="KRH82_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8653919.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            90438..91022
                     /gene="clpP"
                     /locus_tag="KRH82_000624"
     CDS             90438..91022
                     /gene="clpP"
                     /locus_tag="KRH82_000624"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBG8653920.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            91334..92410
                     /locus_tag="KRH82_000625"
     CDS             91334..92410
                     /locus_tag="KRH82_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8653921.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            92477..>93346
                     /gene="bclA3"
                     /locus_tag="KRH82_000626"
     CDS             92477..>93346
                     /gene="bclA3"
                     /locus_tag="KRH82_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBG8653922.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGA"
BASE COUNT        34220 a        12224 c        18116 g        28786 t
ORIGIN      
        1 acggcttttc ttctacgggc ttctatgttg gtttcctgct tcttattatc ttagtggtgg
       61 gaatgtatgt tgcctatacg ggactgataa aacgggaaac cagcaaggca cttcacgctg
      121 ttatcaactt tgtggtggtg ttcgtgttgt ccgcttcgtt tattgcctac gctcccgact
      181 acatcaagaa gataaatgaa ttttcatcag acatcagtac cgcttcgctt gatttgggaa
      241 caaaaatcat gctccccaac tctgacagcg agggcaagga cagcgtagac ttgatacggg
      301 acagcctatt ttctattcaa gtacaacagc cgtggctact cttacagttt ggaaacagca
      361 acgcagagga aatcgggaca gaccgtgtcg aagctctcgt atcggcaagt ccagaggacg
      421 aggacggaaa gaccagagaa gaagtcgtga aaacagaaat cgaggacaac gacaacaaca
      481 atctgatgat accgcaggtg gtaaaccgtt taggtatggt gttcttcctc ttgttcttta
      541 atcttggtat tacgatattt gtattcttgc ttacgggtat gatgttgttc agccagatac
      601 tttttattat cttcgctatg tttttaccta tcagctttct actttccatg ataccgagct
      661 atgaaagcat ggcaaagcag gcaatcgtga gggtatttaa taccataatg acacgggcag
      721 gaataacgct cattataacg gttgcgttta gcatttccag tatgttttat aacatatcca
      781 cggactatcc gtttttcatg gtggcgttct tgcagatagt atgtttcgct ggtatctata
      841 tgaagctggg cgacttaatg agtatgtttt ctctcaacgc tggcgacagt caaagcatgg
      901 gacgcaggat attccgcaga ccgtatctgt tcatgcgaca tcgggctagg cgtatggaac
      961 accgtattgc aagggctgta agtgctggcg gtatttcggg cggtgtggct ggtgcggtag
     1021 ctggaagtgc cgttgctggc aagagatccg aaagaaaaaa tacggcttct aaagaaaatc
     1081 ggggcaatac cacttccagt atgggacagc gtgcaggctc aaaggtgggt gctgtcttag
     1141 atacgaaaaa taaagtgaaa gacaaggcaa acgctgtcaa agagaatatc aaggatatgc
     1201 ccacacagac cgcttatgcg gtgtattccg caaaggaaaa ggcaaagtcc agcgtgtctg
     1261 atttcaagcg tggtatggtg caggaacagc agtccagaca gacgggacgc ttggaaaagc
     1321 aggaacagca taagaaaagt atcgctgtca agcgtatgga gcttcaaaag gcacaagaag
     1381 caaggcatag aaaaacggac ggatcagcga caacgggagc tacccgtccc catgagcgac
     1441 cagccacagc ttcaaccgtt ccaaagacga gtgttgaaaa aatgcaggaa atcaaacgcc
     1501 ctgccacagc tccgacttct aaagcaagtg agccagtcaa gacaaatgtt atcaaagagc
     1561 gtccgttatc ttctggtgct tctgatatga aagcgaccca gtcggcacag ccagtacata
     1621 ggcagaatgt agaaaaagtg gtatcgcagg aaacacgcca gaattacacc aaagaccgca
     1681 ggacaaaggt tcagcagacc caaaccgtcc aaaagaacca gcagaccaca gagaaaaacc
     1741 gtaacattgt aacgaagaaa ggacagaaga aaaaatgaaa ctgaaactga aacatatcgc
     1801 tatcattggc agtctgtttc ctatcctctt ttctctggtg ctttttttgg gtgtcttgat
     1861 tagtgcggac agcgacgacg agaacagcaa tttttcttct ggcattacgg gtatgaactt
     1921 atccgcagaa gtcttgaaac atcagcctat ggtagaaaag tacgccagag aaaatggcat
     1981 ttccgagtac gtccatgtgt tgctggctat cattcaagta gaaagtggcg gtacggcaga
     2041 agatgttatg cagagttcgg aaagtctggg actactgccc aactctttag atacggaaag
     2101 ctcaatcaag caggggtgta agtattttgc gtccctgctt tcttcctgca aaaatcaagg
     2161 tatcgacgat ttgaatgtag cgatacaatc ctataactat ggcggtggct atgtaggata
     2221 tgtggcaggc aaaggaaaga aacacacctt taaccttgca gagagcttcg cacgtgagaa
     2281 atcggttgga aagaaagtaa cctacaccaa cccgatagct gttgcgaaga acgggggctg
     2341 gcggtatggc tatggaaata tgttctatgt ggaattagtc aatcaatatc tgaccgtggc
     2401 acactttgat aatgcgacgg cacaagcgat tatgaatgaa gcgttgaaat atcaaggctg
     2461 gaagtatgtg tatggtggta gtaacccgaa cacttccttt gattgtagcg gacttgtgca
     2521 atggtgctat ggaaaagctg gtatctcctt accgagaacg gcacaagccc agtatgacgc
     2581 aacccaacat cttcctcttt cgcaggcaaa ggctggggac ttggtgtttt tccattccac
     2641 ctataacgct ggaagttatg taacacacgt cggcatttat gtaggaaata acaaaatgta
     2701 ccatgcaggc gacccgatag gatatgcaga cctaagtagt agttactggc aacagcactt
     2761 aatcggtgca ggacgagtaa aagaatagaa aggacttgaa aatatgttta agaagaataa
     2821 gaaatcgaca gaaaatgtca aagaaaaaaa ggtgcgtact gtcaaggtag gcacacataa
     2881 gaaaaccgtg attgcgttgt gggtagtgct tatcgaaagc gtgagctttg gggtgtataa
     2941 gaattttacg gctatcgacc agcatacgac ccatgaaaaa gaagtgatag agcttcgctt
     3001 gcaggacacc aacgggatag aaaatttcgt gaagaacttt gcaaagtctt attatacatg
     3061 gagtaacagc aaagaagcta tcgaagcaag gacgcaggca atcaacggtt atctgacaaa
     3121 ggaattgcag gacttgaatg tggataccat tagaaccgat attccgacca gctccacaat
     3181 tacagatgtg attgtatgga gcattgaaca gtctggaacg gacacttttt ctgctaccta
     3241 cgaagtagat cagcagatag aagaggggga acagacaaca gcggttaagg caacctatac
     3301 cgtaaaagtt catgtggacg atgacgggaa tatggtaatt attcagaacc ctacccttgc
     3361 accagcaatc gagaaatcag actatgaacc aaagacacca gaagcagacg caagtgtaga
     3421 cgctgatacc ataaatgacg ctactgcatt tctggaaact ttctttaagc tatacccaac
     3481 agccacagaa aaggagcttg cttactatgt gtctggaaat gtgcttgagt ctatcggcag
     3541 ggactacctc tattctgaat tggtaaaccc tatctttacg gttgatgggg acaatgtgaa
     3601 agtcaaggtt gccgtgaaat tcattgataa tcagacaaag gcaacacagg tatcgcagtt
     3661 tgaattagtg ctacataagg atagcaactg gaagattata ggataattat tgaaagcgtg
     3721 catttcttta ggaatttgca cgcttttgtt aagagcatta ttctttatat ttatgaaaga
     3781 catcttaaac aaagtattaa tggcttcgca aaattttttt cttaatatat ttggattaga
     3841 aaaagcgcat cttaattgta gacttactat acatatgaat tatgccagtc aacgtattta
     3901 aaatttatgt tgttttattt tgttgtaaat cgcaagaata gataagagta atcaatggtg
     3961 aaggggaatt attaaaaata ctattggttt cttctgtccc gttccaattt gcgcattgta
     4021 ttttttcata aattacagag tggtcaatta tgtagttcag atattccata caaactaatt
     4081 gtattgtttt tacactcgtt ttccatactg ccacttttgt cattctatca ctcataatac
     4141 aaatattatt atgagcaact tttctaagta gttatttgga aatttgatac atggtcaagg
     4201 tgaaaaccaa gaagaagttt gtcagcactc atatgtgtca aggggaaatg cctatttatg
     4261 tgcgagagcg ctatgagaaa atgcttgccg tatccatccg tgctccaaat ttagaaggaa
     4321 tggttgaaaa ctttgataag gatttatctc accctaacga gacggatttg atcgagctga
     4381 aaaatgccat atcaaagtaa attgcaagaa aaaagcaaga atataaatat agaattttca
     4441 gagcactgtg ttaaaatgtt attacttata cttataaagg aggggatgtt tcgtgtcaaa
     4501 agcaacacta tttgatagtc gtatcaaaaa atacgcatac tgtagaacat cagaaattta
     4561 tcgagacatt ggctcatctc cggatggttt atccattgag caaatcggtt caatgcggga
     4621 gaaatacgga gcgaacagct tcaatgggcg gaaaaatgat acgacgatgc aacggttgag
     4681 acgggcattt attaacccgt ttcatgtgat tctttttgtt ctgggcattg tttctcttgt
     4741 tacggatgtt ttcgtagcat ccaattttgc gagaaatgct actaccgcca ttatcatctt
     4801 ttccatgatc gtaattagtg gcgtaattcg tctgattcag gagctgcgag caaagagcgc
     4861 tgctgctcag cttgatcgcc tagttcatga aagcgtcaca gtgaggcgtg atggaaagtt
     4921 aatagagatt cctggcgaag aattagtggt aggggatatt gtactattct ctgcaggtga
     4981 tcgtgttccg gcggatatca gattgacgaa gattacggat ctctttatct ctcaggctgc
     5041 gattactggt gagagcgcca tcattgaaaa gagctgccga aaactcagtt acggagagca
     5101 ggatacactg actcagcttg aaaacctcgc ttttatggca accacagtca tcagtggaaa
     5161 aggggaaggc attgtactgg cagtaggcaa agataccctg tatggaggat ttaccaaacc
     5221 ggattctgat gataaaaatt cctttaaaaa aggagccgat tccatcgcct gggtgatgat
     5281 acgttttatg gcgatattag ttcccattgt atttatatta ctggggatta ctgatggaaa
     5341 atggatggaa tcctttgctt tcgccctgtc agttgctgta ggtctgatgc cggaaatgct
     5401 tcctatggtt attacagcct gccttgccaa aggaagtctt gctatgagca aaaagcagac
     5461 cattatcaag gatattaatg ccatgcagag ctttggtagc atggatgtgc tttgtatgga
     5521 taaaacagga acacttacca atgaaagcat cctgctggaa tattatatgg atatttttgg
     5581 aaatgaaaat gcagaggttc ttgatcttgc ttatctgaat agctgctatc attctggtgt
     5641 ctgcaatacc attgataatg ctattcttgc ctgcaatacc atgccagggc gggaagccca
     5701 ttacgcaaat cttctgacaa aattccaaaa agctgatgaa attccctttg actatgctcg
     5761 taagtttgtc agtacacttg tacaggatag caatgggaat agtcagctta ttatgaaagg
     5821 tgatattgaa catatattct cacgctgcaa ccatgtagaa tatcgtggaa aacttctccc
     5881 catggggcag gatgcgagac atagtgtatc ttctgtagta ggtgaaatgt tacaggacgg
     5941 aatgaaggtc attgcggtgg cacgaaaaaa tgtgggagcg caaaagaaaa taactcctga
     6001 tgacgaatgg ggcatgactc tagttggcta tctatccttc tttgatgcac caaagcagac
     6061 agcaaaggag tctgtaactg cactcaaaag attaaaagtg atccctaaga ttctgacagg
     6121 ggaccaggca gcgattgctg tgtctgtttg ccgccgggtg ggtatttcta cagagcgtat
     6181 cttaactggt actcaactgg atgaaatgac agactgtgaa cttaaaaagg ctgtggaaca
     6241 tactcatgtt tttgcagagc ttactccggg acataaggtg cgtcttgtct ctgctatgca
     6301 ggataatggt cattccgtgg gatttcttgg tgatggagtc aacgacattc cggcactgaa
     6361 tgaagcaaat gtgggaatct ctgtagatac ggcagtggac gcagcaaaag atgctgccga
     6421 tgtggttttg ctgcaaaagg acttgaatgt tttggagcaa ggtgtaatgg aggggcgaaa
     6481 aacttttacc aatatgctga aatatattaa aatcaccgct agctctaact ttggaaatat
     6541 tttttccatc atttgtgcca gtgccttttt accgttcctg cctatgactt caattcagat
     6601 tctgcttttg aatctgctgt atgatacgtt gtgtattgtg cttccttggg acaatgtaga
     6661 tgaggaagag atgctgtccc caagagactg gtccggcaaa acactgagac agtttatgct
     6721 gtctttcgga ccgatcagtt ctctgtttga tattgtcacc ttcctatttt tgtattattt
     6781 cctatgtccg atgctatgtg gaggggcaac ctatctgcag cttacagatc cttccctgca
     6841 acttcagtat gtagcactgt ttcagacggg atggtttttg gaatctatgt ggacacaggt
     6901 tttgatttta cattttctgc gaacttccaa gattcctttt ttccagagca gggcatctgc
     6961 accggtcatt tctataactc tagtggggat tattgctttt acttccctta catttgtcgg
     7021 cggtgcgtcg ttgtttggac tgacgaaatt acctctttgg tatttcgtat ttttactgct
     7081 ggtggtatct ctctatatgc tgctgaattc agtagccaaa tatttttata agaaaaaata
     7141 tcaagagttg atttaagagg aggcattcat gatgaaaaag aatattagtt atattccgat
     7201 ggattcggct cttgaaatct ggctattaga aaaactacta agagatccac cggacagtga
     7261 ttgtgcgaag gatttacttt ctggtattca ggagatgatt cgtggagagg tatcttcgtt
     7321 attgttagga gcatcagaag aaagcgattg gccagtgggt actctgtcag atagaatcct
     7381 ggcaggggat ctggaaattt atccaagagg cagaaaagta ctgataaaag gttctgaagt
     7441 caacctgact ccaaaggaat ttgatatttt gtactttctt gtccagaaca aaggtgaagt
     7501 ttttacaaag gaacagattt atcgtgccgt atgggaggaa gattatattc tggataacag
     7561 caacattatg gcttttatcc ggaagttgcg aaaaaagatt gaacctgctc cggattgtcc
     7621 cacatatatt ttgaccatct ggggtattgg atacaaattt aatgatcaga tatgacaaag
     7681 acggactaag accattttcg gtttcagtcc gtctattttc ttaccaaatc gcaagaaaat
     7741 cgcaagactt tagccatagg attgtatttg gattttttat atactgttag tagttaaagg
     7801 gaggtgtttc atatgtttta cacagatttt attttgagaa ttgccctctc cttaacactt
     7861 ggatttctta ttggattaga acggcaattg actggtcatc ctgcaggtat tcgtatcaat
     7921 gtgttaatct gcatgggtac aagtttcttt accttgtttc ctatgctcta cggttcggat
     7981 caggtattcc gtgtcggaag cagtattata tccggtgttg gttttttatg cagtggtgtt
     8041 attttcaagg acagagggac agtacgtgga atgaataccg ctgccacctt atggtgtact
     8101 gcagcgattg gaattcttgc aagtacggga atgtatgcaa tggcgatcac cgccgctact
     8161 attttaattg gttccaacct gattctacgt ccctttgcaa gaaagtttca cccaattact
     8221 tccagtgatg aatctgaaaa gcagtatcgt atttcggtta catgtcagga aaaggcagag
     8281 caggatatac gcttattgct gattaacagc aattcctgta agacgctctt tttgaacaat
     8341 ctggaaagcg gtgatgtggt tggtgacaag gttgagattg tcgcagaata ctgttctgtc
     8401 ggaaaatcca aaaacaatat tttagaagga atcgttgggc aggtattggt aattccggaa
     8461 gtgattagtg ctggttggga ggtgttgtga gtgaggagag aaatcgaaga tttgaaacga
     8521 gcaattcttt ttgctttcta ccctgtattt acaatcttat gtagctattt gggttggaat
     8581 ttctttgaac aaagaatggt aatctttaag atatggtatc aggtgagtat tgtgatctgg
     8641 tttattcttg ctgttactat tattgtgctc ttcattaaac ttctgaagct gacaaaacta
     8701 agaaacaggt ttaagcattg aaaggaggaa caaacgatgg attttacatg tatctttttt
     8761 ggaattttat ttactcttgc aggcttttgg ttggcctttg gaaaaggata tcgtcatctt
     8821 tccctgtgga aaaatatgcc gcaggaggag aaagataaaa ttaatattgt cccgctttgt
     8881 cgtaatgttg gagaaatgat tgcgttaaat gggattatat tcttaatgaa aggatttttg
     8941 ccgggatttt caaaccactg gtttgtattt gcaataatcg catggctgat tgttgccggc
     9001 tttgatgtct ggtatatcga aaaaagtgtc cgctatcgca accaataatc cacattgagg
     9061 tttcacatag atattttttt aagattgtga ggtgaaagac atggactctg atgtcagtcc
     9121 acgaaggcag agaatattat atgagaattt ggagattccg tgtcgctcat ataatattcc
     9181 ttgcccctat gaaaattcaa ggaggtaaga ccaatgaaca aaaaagaaaa tcgtatggct
     9241 attcgtcaga ctgtagaaaa agcagtcatc cgtgacgaac agaaccgccg cattcaattt
     9301 gcggcaacca atcctattaa agaagtttta aaaaaacttc ataccacact tcgtggctta
     9361 gaagtagatg aagtatccgt aagtcgtgct aaatatggta ccaataaagt cactcatgaa
     9421 aaaaagaaat ctctggcaaa acgactggtt ggcgcattta tcaatccatt taccgccatt
     9481 ttattttgtc tggctttagt atccacaatt acagatatga tttttccgta tttttctctg
     9541 tttggcagtg tgccagagga ctttgattcc ctgactgttg taatcatttt aacaatggta
     9601 ttcatttccg gtacgcttcg ttttgtacag gaatccagaa gcggaaatgc agcagagaaa
     9661 ttgttagcca tgattacgac cacttgtaca gttactcgta gaaactatga aaaaaaagaa
     9721 cttcctatgg atgatttggt ggtgggagat attgtgcatc tttctgctgg agatatgatt
     9781 ccggcggatg ttcgtatttt ggatgcgaag gatttgtttg tcagtcaggc aagtcttact
     9841 ggtgagagtg aacctattga aaaaacaccc aatgtaagtg ctcagaaaga aagcgtgact
     9901 gattacacaa acattgcttt tatggggagt aatgtaattt ctggtagcgc aacagctgtt
     9961 gttgtttgtg ttggcgatca tactctgttt ggctctatgg cgtccgcagt tgctggagaa
    10021 gcggttgaaa caagctttac caagggtgtc aatgccgttt cttgggtatt gattcgtttt
    10081 atgctcatta tggttccgct ggtattcttt gtcaatggta tcaccaaggg cgattggttg
    10141 gcggccttct tattcggcgt ttctattgct gttggtttga caccagaaat gttgccgatg
    10201 attgtaacaa cctgtcttgc gaaaggcgct gtttccatga gcaagaagca gacaattgtt
    10261 aaaaacctca attccattca gaacttcggt gctattgata ttctctgtac tgacaagact
    10321 ggcacgctga cccaggataa ggttgtgctg gaataccatc tgaatgtaaa tggcgaggac
    10381 gatacgcgag tactgcgtca cgcttacctc aatagttact tccagactgg ctataaaaac
    10441 ctgatggatt tggcaattat ccataagact gaggaagagg aagccgcaga ttcgcgtctc
    10501 attgacctgt ctgaaaacta tgtgaaagta gatgagattc cttttgactt cacacgtcgt
    10561 cgtctgacta cagtggtaca ggataataag ggtaagaccc agatggtaac aaaaggtgct
    10621 gtggaagaaa tgctctctat ttgtgcgttt gcagagtgta atggaggagt gcagcctctg
    10681 actgatgacg ttcgttacag aattctggag acagtggaca atcttaacga taagggattc
    10741 cgcgtactag ctattgcaca gaagagtaat ccttccccaa tcggcgcatt tggtgttaaa
    10801 gatgagtgtg atatggtact gattggatat ctggcattcc ttgatcctcc aaaagaatct
    10861 actgcggatg ctattaaagc tctgaaagac catggtgtta taaccaaaat tttgacaggt
    10921 gacaacgaca aagtgactcg aactatctgc aagcaggtgg gattagaggt tcgcaatatg
    10981 cttctcggtt ctgatttgga acaaatgggc gatgcagagc ttgcaagagt ggcagagtct
    11041 acagatgtat ttgcaaagct aacccctgat cagaaagccc gtgtggtttc tgttctccgt
    11101 gaaaatggtc atacggtcgg tttcatgggt gacggtatta atgatgctgc agctatgaaa
    11161 gccgccgata ttggtatttc ggtggatacc gccgtggacg tggcaaaaga atctgctgac
    11221 attattctat tggaaaaaga tctgatggtt ttggaacagg gtattattga gggacgaaag
    11281 acatatgcca acatgatcaa gtacattaaa atgactgctt catccaactt cggcaatatg
    11341 ttctcagtgc ttgctgcatc tgctttgtta cctttcttac caatgatgag tgttcatctt
    11401 atatttctaa acttaattta tgatttatcc tgtactgcaa ttccttggga taatgtggat
    11461 gaggagttta ttaccaaacc tcgtaaatgg gacgcttcta gtgttggaag ttttatgatc
    11521 tggattggac caaccagttc tatctttgat tttacaacct atatttttat gtactttgta
    11581 ttttgtccat tgttcgtatc gaatggtgta ttatttaatg atttgcctgc tcatttcagc
    11641 ggtgcagaac tggcaatgct tcaggcacag tatatcggga tgttccaagc agggtggttc
    11701 gtggaatcta tgtggagcca gacattagtc attcacatga ttcgtactcc aaagctgcct
    11761 tttgttcaga gtcgtgcatc agctccggtg actttgctaa caatgactgg aattatagtt
    11821 ctgaccatta ttccgtttac tgtgtttgga actatgcttg gatttgttgc attgcctgca
    11881 gcatactttg cttatctgat tccatgtatt ctgctgtata tgactttggc aacaagttta
    11941 aaaaaagcct atgtccgtca tttcggagaa ctgctttaag gaggtggaat gatgaactgg
    12001 aaagaacttt ggatgaccct ttttggaact accgaatggc ttggtcttaa tatcggcttt
    12061 tgggtggcta tggcagttgt gttgctgatt gttattgtaa tgaatgtagt gttttggtcc
    12121 atgaaaccaa aaaaagacac aaaagagtct tataaataag atatcagtat gaatgaatca
    12181 ggggagatgc acagtttttt attgtggaat ctccctatca tatcaaggcg cattcaattg
    12241 tggcaattta gtagtaaagt atgtgttttt tatcattgaa ttacctataa atgctgtata
    12301 taagtggata attgtaattt cgatataaaa attatggtac ttaaaagaaa tttcgttttt
    12361 tattgtttgt ttacgcgtct ataacgaaat cgtgaaataa tattcaaagg tagattttat
    12421 tatggaatgt atgtctgtag aagaagcttc gataaaatga ggagatctct gaaagaagga
    12481 taaaaaaatt atgtaatgga aacagaatcc caaatctatt gtaacaacaa ttacaggtaa
    12541 tgaatggtta cgtagattga taattcctat tcaaattatt atctatctta tattgagtgg
    12601 tgttttgtaa ttacattttt atacaaaaag aatatgttga acgcacaatg ataaatattt
    12661 tgtattcccc aactaataga ataaagtttt tgcttggaaa gtatgttata taggcattat
    12721 ggtttgtaat gatcacgttg acagattata ccgctatata tgaagtcaaa gaacttaaat
    12781 catttacaag tgagataatc tatctaagtc taaaaaactg gatttctcaa tctattgtca
    12841 atgagtccat tacttattat ttgtgttttg caaagaaatg ttttctactc tagtttactt
    12901 tttagttact aaatatcggg aattggtttt gttggactat attgatctga aagtatacaa
    12961 aatattattc cgtggtctgc tgtaacccct ataagtttat tagatgcaca aggattgcta
    13021 ccttaatatt tcaattctac tttgttattt tgcaagactg attataaata catactgctt
    13081 tagagggttt agtttagttc tttttgaact tttgaataag acgacggtta tatagccgcc
    13141 gttttatttt tgcctaacgt tggacaaatt actggatggt cttgttttat cggctctagg
    13201 ggtagccgta tgaaacactt acatattcaa caactttcga ccatcggtag ttcattaaaa
    13261 aaacatttaa attctacaga acataatgct cctatatgtg gttttttaca gcatataaca
    13321 ggaataattt gtttagcaca agatcagtac gtctgtattg cccttgtgct tttttactgc
    13381 ataaaacttt ttcaaaaaat ttttgtggtt gggtatcaga tcccaccttt cacggtgagt
    13441 gttagtgcga aaagaggtag aagtcttttc gctttagcaa ctttcgctgg aaagggggtg
    13501 agattatgaa accatcttct ttcgagggcg ctatcagact tcaatttgat tgtctggctc
    13561 gcaaggttgt aggacgaact gtaaagaact atgaccgaga gcttggcaga cgtgcaagac
    13621 gtgaaacgcc gttctgtgat ttatctgaaa tggagttaaa ccagatcggt gtcatggacg
    13681 agtattgcgt tgagtttacg tcatttgatg tatttggttc agaagtccat atctatgatg
    13741 aacgcttatg tgaagctatc aaagaattaa cagaaagccg acgtaacatt ctgcttatgt
    13801 cctactttct tgaaatgacc gacgctgaaa ttgcagaggt tatggaaatg gaacgatttt
    13861 ccgtatgtag aaacaggctg cacacattaa agcttattaa ggatatgtac gaggaggaat
    13921 aaaaacatga tgaagtctac aaaaaagtgt ccatcattct cgaccatcag ctctgcagct
    13981 gacggtaacg aggtggcaat tgaaaagatt ttgaaccatt atgacgctta catatcaaaa
    14041 gccagcctac gcccgttcta tgacgaacac gggaatatgt atatcgtgct tgatatggaa
    14101 ctgaaaggca ggatacgggc agcgttgatt aaagtaatct tagggtttga agtcaaagtg
    14161 aagtaaatat aacagagagt atctaccacc tcattttaac tcttttccgt tctttgacaa
    14221 gtgaatacag taatcagata cgtttgatat acgacgagcc agcggactgg aacgccacga
    14281 ccactgaaag ggggaaagca gcgagcgatt atgccagtga accgcaagcg atctttggaa
    14341 aggttgctgc catgactcgt atatctgaat aatgatacac ccgtatgaca cggttcaccc
    14401 atcagaatgg gaatggtgaa agtccagtgg agctgccgaa gccgtctgat tacttccata
    14461 aataaaaaag caaggagggt tttaatgaat aatataatta ggtatagtat gcaaattgct
    14521 atgttaaaac aactgcttgc ccgtaaactg atttctgaaa aagaatacac tcttgtaaaa
    14581 caaaggctga tgaaagacta taaggtgctt tctgacataa ctgcttgaat tgtgtttttt
    14641 aaagtagtac aataacaata tgaaaggaac acaaaataag gaggtgtact atgcaggaag
    14701 ttgaagtaat aaaagcaaaa aatgttttgt caagacaagc ccgtggaaaa gccattgagc
    14761 gtttgcgtgt agctgcatat tgccgtgtaa gtacagatag cgaagatcag ttaaacagtt
    14821 ataaatcaca agttcagtat tatactgaca tgattaagaa aaacaaggaa tgggtgttag
    14881 ctgacattta tgctgatgaa gcaattacgg ggacacaagt aacaaaacga gaagattttc
    14941 agcgtatgat aaatgactgt atgaatggtg aaattgacat ggtatttaca aaatccatat
    15001 caagatttgc cagaaatact ttagacacat tgaaatatgt tcgtatgcta aaagagagaa
    15061 atatcgccgt ttattttgaa gatgaaaaaa tcaatacact tacaatggat ggagagttat
    15121 tgcttgttgt tcttagttct gttgcacagc aggaagtcga gaacatttca gccaatgtaa
    15181 aaaaagggtt gaaaatgaaa atgaagcgcg gcgagctggt aggttttcaa ggttgtattg
    15241 gatatgatta tcacccagag gataagacaa taactgtaaa tcaagaagaa gcagagattg
    15301 tcagatatat tttcaaccgt tatgttgatg gtgctggtgg ttctgttatt ggacaggagc
    15361 ttgaaagtct aggttataaa acgaagtatg ggagttccac atgggcacca tctacggtta
    15421 ttggaattat taagaatgag aaatacaagg gtgatatact cttaggcaaa acttttactg
    15481 ttgatccgat ttccaaacgt cgccttgaaa acatgggtga agaagataaa ttttatatga
    15541 aagatcacca tgagccgatt attagtgaag aagtttttga aaaagcacag gaaattctta
    15601 atcggagaaa taagaaccga acaacggtag gcagcggtaa gcgtgagaag tatagcagga
    15661 aatacgcatt tagctgtatg ctagaatgtg gcttttgtgg tggtacttta acaagacgta
    15721 attggcacag tggctcacaa tacagtaagg ttatatggca atgtgtaacg gctacgaaga
    15781 aaggaaagaa attttgtaaa catagcaaag gtattccaga aacagctatt gaagaagcat
    15841 ttgtagaaag ttatcgttta ttatgtgatg ataataaaga tgttctggaa gaatttttgc
    15901 agagaatgga cgatactctt agtagtagtg tggtgtcaaa acaacttgca aaagcggaaa
    15961 aggagataga cgcattagag aagaaaaaaa gtaaacttgt ggatatgcgt ctggaagaaa
    16021 ttattgataa ggaaacctac gaaagtaaat atgctgattt agtaagtaaa caagaacagc
    16081 ttgttgaaga aagacaaaag ttacaagaaa cttctgataa tgagaaagac ataaaaaaac
    16141 gtttgaaaga gtttaagaaa actctggaac agaatgaggt tcttgataaa tttgaccgct
    16201 atgtgtttga aagcattgtt gaaaaagtaa ttgtaggtgg acttgatgaa aacggaaatg
    16261 ttgaccctgc acagttgacc tttgtttata aaacaggctt gaagaatagc gtagatggtg
    16321 ctaaatttaa accacaaagg aaaaatgcaa gaggacggca taggactaat gaattgtgtt
    16381 cacatgacag caacgaggtt gataaaatgt gttccgatag tagtaacgac acatgtggag
    16441 acggtagcac tattgtccaa acttgatgtc gataagcata ttgatgttga aattaagctg
    16501 gatgagtttg atttgacaag tgcagagagt aaagcaacat acgctcaaat caaggagtat
    16561 gtattagaaa aatttgggct aaaagtttct acactctata ttgcacaaat taaaaagaaa
    16621 tgtgggattg aaatgagaga gcattataat aaatctaaaa aagataatca ggctatccca
    16681 cagtgtacgc ctgaaaaaga agaagctatc atggatgctt taagacattt taaaatgatt
    16741 tagtataaat ggagggtatt tatgagatgg atattaaaaa taatcttatt tccaattagc
    16801 ttgttgttaa gtattctcac tgcatttctt tcatttttac ttggaatagg aacagcaata
    16861 ctttacttgc tgatgatgtt ttgtatattc ggagcaatag catcttttct acaaaaagaa
    16921 gttaccatcg gcatagaagc attgattatt ggatttttag ttagcccata cggaatgccg
    16981 atggtgggag caactgttat agcagttttg caaggagtaa atgagagaat aaggttagtt
    17041 taaattaaag tattgataaa tttgaatttg ccgtagcaat tataagtcat ttggtaaaaa
    17101 ataaggtaat aaaaataggt gatggaattg tactattctt ggcgaattaa tagatgtatc
    17161 aaaaaataaa ggagtaatct aaaatgagtt catataattt taattatata ataccagata
    17221 attttaatag gaggactttt caatatttac aacagaaaaa tagtaacctt gcaacaacat
    17281 ttgctagatg cacatatgag tatgaagatg ttggattagc ctattatgct ggattaaaaa
    17341 caggggataa ttggaacaag catgctttag attttactat tgagggtaat caaaatgata
    17401 ttgagatact gcaacaatta aatagtgatt taaaagatgc tattgataaa gctttaaaac
    17461 caagtgtttc agggcttata ataagacata tttattattt accttctgaa gaaagtacat
    17521 tagatttacc acagtctaat gtagctagat taaatgcgga tatttcaaca gcagaaggag
    17581 ttttaaaaga tttaatccag gtaagcgaac gactatgttc aaattcatta tactcagata
    17641 taagtcttga aaatagtata aacgattatt ttcgtgatgc actttctttt atggggtata
    17701 acgaggttaa agatcaaacg cgacatggag tttcaatttc tgaaaaagac gctggagagg
    17761 tcgatttgtt acttacaaaa agtggtaaag aaatagctat ttttgagggg ctaaaactgg
    17821 atagtgttaa ttcaaaatat attgatgaac atataaagaa agctatagat aattataatg
    17881 cgttaggtac tgctactttt gttgtggcat atgttaatgt agtaaactat gatagatttt
    17941 gggagaagta ctatgagcat atttccaatt atgcacataa tatggaatgt aaatcagcca
    18001 tgaaagagtt aacacaccct aatgctgcaa ctagaatagc atatgaagta ttatcgaagg
    18061 atggatatga ttttccagtt tattttatga caataaaaat agcttagtct tataaatggt
    18121 aattagtcga tgagctatta gtaagattca ttcttgtttg caaaataaaa aatttcataa
    18181 aatcggttac aaaaggcggt agagaaaaag ctatcgtctt tttatttgaa taaaaaaaga
    18241 aaggagtgtt tgatgagtat gtatttattt gatgaacaac ctatagttgc gaataaaact
    18301 cttgctagag aaataggatt aaacgaagca ctcatactac agcagattaa ttattggata
    18361 gaaataaata aaaaatcagg aaagaattat catgatggta aatactggac atataattca
    18421 attcgagcat ggcaagaaaa tgattttgac tatatgagct ttgatacagt aaaaagaact
    18481 ttttcaaagt tagaaaaagc aggttatctt ttggttggta attataataa agatccaaga
    18541 gataaaacaa aatggtatac aattaataat gataagcttg aagaattgta tgtggatatg
    18601 gaattaaaaa aacaaaaaat acaaacagag gcattaaaaa aatctatgcc caatacatta
    18661 gggcaaaatg caccaatgga taagggcaaa atcaaccaat gcaataatgc agactgcact
    18721 aatgcacagg ttcaaaatgc actaatgcaa agggataatt tgcaccaacc attaccagag
    18781 aatacaacaa ataatactac aaataattca gcagatattt ccatccatcc ttccatcaaa
    18841 gaaaagaatc aattattttc agagaatatg aagggaagga ggatagatat aagctataaa
    18901 aatatatatc aaaattgttt agaagaattg cgacaccaaa caggatatta tgaacatatg
    18961 agcattggga ataagattgt ggctgaagag tttgatgaaa tattaaagat actggcagac
    19021 gtaatggtat tagatgatga atctttcatt actatcaacc aaacaaagat atctgtacaa
    19081 gtagtaaagg aaagatttag ggaacttaat tcagggcatt tagagtactt agtaggagta
    19141 ttaagagaaa atgaatacaa gattagaaat ataagagctt ttgtcctgac cgccgcttat
    19201 aatgcaccaa ctggaataga tgcctattat tcggctcttg taagctatga tatgagagga
    19261 ggatattgat gtgatcaatg aagaaatagc aagaaagacc ttaaatatgg aagttagagc
    19321 tgccaaagta acaggaaagt taattctgga cttattaaag aaactgatga aagaagcaga
    19381 aaaacttgga ggacttgaaa aactggttaa tgttaacgga aatgaagtaa agctaaaaga
    19441 tatggttaaa aagggacagc ttgaagaaat cccagtggaa gaagctgaac ttaaagaact
    19501 taaaaaagag ttgaatagat acggtgttaa attttcagtg atgaaagata aagagacagg
    19561 taaatactct gtattctttc aagccaaaga tatgaaagtg atggataaag cttttaagca
    19621 cgctctttca gaatcagaaa agaaagcaga aatgaaagaa tctattcaca aaaatattga
    19681 gaaatttaag gagatagcta aaaactctat ttcaaaagat aaaatcaaaa ataaacaaaa
    19741 ggagcaaagc ctatgataga taagatacta aaagagatca aaggcttatt taaggtgcaa
    19801 gataaggcaa agtttctaaa gcagaacatt ccctatcttg catttttcta tgttggtaat
    19861 atcttctctc atcatgtaag agcatatact ggtggcgatg tgatagacaa aatctttcaa
    19921 ggaatactag agcttaatat tatgagtttt cttccaagtc ttcatccaac tgacattcta
    19981 ataggcatag gagtagctgc tttaatcaaa tttatcgtat ataccaaagg gaaaaatgcg
    20041 aaaaagttta ggcagggtaa agagtatggc tcggcaagat ggggaactag aaaagatatt
    20101 gagccgtaca tggatgaaaa gtttcaaaac aatatcctgc ttacgcaaac agaacgatta
    20161 accatgaacg gcagacctgc taatccaaag tatgcaagaa ataaaaatgt gcttgtaata
    20221 ggaggttcag gaagcggaaa aactcgattt tatgtaaaac cgaacttaat gcaaatgcac
    20281 agtagctatt gcgtaacaga tccaaaagga acgatagtcc ttgagtgtgg taagatgctt
    20341 gaagataatg gatatgagat aaaaattcta aataccataa acttcaaaaa gtctatgaag
    20401 tataatccat ttgcttatct tagaagtgaa aaagacatac tcaaattggt gcaaacaatc
    20461 attgcaaata ctaaaggaga gggagaaaaa gcgggtgagg atttttggat caaagccgaa
    20521 aaactctact atacagctct gattggatat atcttctatg aagctccaag ggaagaaaag
    20581 aactttgcaa cactccttga tatgatagat gcttcagaag ttagagaaga tgatgaaacc
    20641 tatatgaatc caatagatag actctttgaa gccttagaaa aaagagagcc tacgcacttt
    20701 gcggtgaagc aatataaaaa atataaactt gctgccggaa aaacagcaaa atctattctc
    20761 atttcttgcg gtgcaaggct tgctccattt gatattcaag aattgagaga tttgatgaaa
    20821 gaagatgaac tggaacttga tactcttgga gatagaaagg cagcactctt tgtcattatc
    20881 tccgataccg atgatacctt taactttgta gtgtctatta tgtattcgca gttatttaat
    20941 ctcttatgtg ataaggcgga tgatgtatat ggcggacgat tatctgtcca tgtgaggtgt
    21001 ctacttgatg agttcgctaa tatcggctta attcctaagt ttgagaagtt aattgcaaca
    21061 atccgttcaa gagagatttc agcaagtata atacttcaag cacaatctca gttaaaagca
    21121 atctacaaag ataatgcaga taccattgta ggtaattgtg atagcacctt gtttcttggt
    21181 gggaaggaaa agactacatt aaaagagctt tctgaaacac ttggaaagga aacgatagac
    21241 ctttacaata cttcggaaac aagaagcaat caaaagagct ttggattgaa ttatcaaaag
    21301 acaggaaagg agctaatgag ccaagatgag ataacagtaa tggacggtgg aaaatgtata
    21361 tttcagctta gaggtgttcg acctttttta tcagataaat acgatattac aaagcataag
    21421 aattacaagc tccttgagga ctatgacaag aggaatttgt ttgatataga gagctacatt
    21481 aagcgtaaag ggaaagtgaa aatgaataga catactgtaa ttacaagatt gtaacattct
    21541 ccttatcact atatgtagat gtataaattt ggtataatgt tgtttaaata aatgatattt
    21601 tatgtatgaa acctataata tttgtactaa tactgtgggg taggaaaaga aaacttccta
    21661 tatactaaaa tcaatcgaaa gaaaggagga aattagaatg aatattatca agtcatttaa
    21721 cagtacaatt gattatcttg aaacagttct tgatgatgaa attgatgaaa agaaagtaac
    21781 tagaatatct ggatattctt attcgatgtt cagtcgcttg ttttctattc taactgaaat
    21841 gacactttca gaatatttaa gaagcagaag attaacggaa gctgcgatta tattaagaga
    21901 tacagatgaa aaaattattg atgttgcatt caaatttgga tatgagtcat cagattcgtt
    21961 tgggactgct tttaagaatt ttcatggatt tactccttct gaggtaagaa atggaaaacc
    22021 ctttaaatta gtttccaggg tgcaattagc attaagtgta agaggaggaa gaagtatgaa
    22081 tattaggatt caaaagaaaa aagcatttac agttgcaggt gtaaatcaac aaaacatcaa
    22141 ttcatcaata tgtgcaagcc tatggcaaaa actattttca aaggtatctc atgaagaaat
    22201 gttaaactta gggaccggag aagctgtagg agtatgccat gatatattaa gtcttgataa
    22261 tcatgatgtt ttagatagca acacgataaa ttatatggca ggatatattg ttacagatgt
    22321 agataaggca agaagtatgg gattagatat tttagaaatt ggagaaacag agtatgcggt
    22381 tgtagagtta acaggtagtg ttccagagtg tattcataat ggttggaagt atgcgatgga
    22441 agtattcttt cccgagcatg gatatgttca ttcaggaaag ccggactttg aatattatta
    22501 tgaaggagat atgtatagta aagactacaa aatggaactt tggattccag tatgtaaatc
    22561 ttaacaaatt tcagtctata gttttaaaac aaaatatata aaatacaagg tgatagaaag
    22621 taaaagctat tgcctttttt atgtaaaaat ttaaggagat agaatgataa ggataagaag
    22681 tcctacttaa atgaaaataa aatagtaaga gtataagcga ttggcaaagt atgaagtccg
    22741 gtcgcttttt ttatttaaaa gaaaaggaga aattttaatg aagcaagaaa tgattaatat
    22801 taatgccaac ttgttggcag aaccgacttt ctcaaaattt gaaaaagagg gagaaaaagt
    22861 ggaagttgca aacttcacgc ttgtaaaaaa gtacggaaaa ggcaaggagt acattaactg
    22921 tgcagcttat ggagaaaagg cagaaatagc aaaagccttt gaaaaaggtg atttaatcca
    22981 tatctttggc tactttaaga agcgtgaaaa agagggaaag acttacaaga actttgttgt
    23041 gaagtcatat aacaagattg aaaagaaaga aaaaaacgag gaggaataaa tcatggaatt
    23101 ttttggacaa gcagtcaatg tattaaagat tttagtaatg gcagtaggtg caggacttgg
    23161 agcgtggggt gttatcaatc ttatggaagg atatggtaat gacaatcccg gagcaaagtc
    23221 tcaggggatt aagcagttaa tggctggagg tggaattgtc cttattggat taaagctgat
    23281 tccacttctt gcaaatgtac tcagataaga agaaaaggag aaactaaatg tttggtatat
    23341 tcgacaaaat agaggagttt ttcaaagagc ttctattagg cggtatccaa gcaaatcttg
    23401 agtctatgtt tcttgatatc aacgataaag ttggtgcggt tgcaacagat gtagggaaaa
    23461 cgcctatggg atggaatgga caagtattta gctttattaa aagtattaac gattctgtaa
    23521 ttattcccat agctggtcta atcattacgg cagtcctttg tatcgagctt atcaacatgg
    23581 taatgcaaaa gaacaatatg cacgatacgg atacctttga atttttcaag tacatcataa
    23641 agatgtggat tgccgtatgg ttagtatctc atgcctttga gttttcaatg gcggtctttg
    23701 atgtggcaca acatatggta aataaggcgg caggggtgat aaacacctct gccaccgttt
    23761 ccggagatca gatagtggca atgatggata ccttaaaaga aaagggactt ggagaacttg
    23821 tcatgattct ctttgaaacc tctctcatca aggttgctat acaggtaatc tctgttgtaa
    23881 tcatgcttgt ggtttacgga agaatgtttg agatttatgt ttactcatcg gtttctgcaa
    23941 taccgtttgc cacaatggga aacaaagaat ggggacaaat cggaacaaat tacatcaagg
    24001 gactatttgc acttggacta caaggactct ttttaatggt ttgtcttgga atatacgcag
    24061 tattagttaa gacaatacag ataacagata tacacacaag taccatgacg atacttggat
    24121 atgcggtttt gctggggtta atgatgctaa agagcggaac actggccaaa agcgtattaa
    24181 atgcacacta aaaaagaaag gaaagatagt atgaacaaaa gaaaaacagt atttacagca
    24241 gtagtaatcg gagcaggcat tatggcggta attgacagaa tcagatttca taacaaagtg
    24301 gacgaattgg aagaaagaac agaggacatc ggtcgttgcc ataatgattt ttgcttaatg
    24361 cagcaaagat ataacagaag tacagatgaa cagattgtaa gtattcagga agaaatcggc
    24421 tccgtatatg agcatataga agaactttca aaggaaaaag aagatgggag gtaagttatg
    24481 gcatatgtac ctatccctaa agacttaaag aaggtaaaaa caaaggtggc atttaacctg
    24541 acgaaaagac agcttatcgg ttttacgatt gcaggactta ttggaatacc aatctattta
    24601 tttatgcgaa aggtagttcc aaatgatata gcagtcatat ttctcattgt gtccacactc
    24661 cctatatttt tcatcactct ttttgaaaag gacggactga catttgaaaa atattttaaa
    24721 tatatttacc ttcataagtt ttatcagcca caaaaaagag tgagaaagga ggtttatctt
    24781 gaaagacaaa agaaagattc agcagctaaa gttagaacaa aacaaaaaga agttaagaag
    24841 tcaaagacag gacttaaagc aaaataaggg aaaatctaaa aaagataaag gcgggctact
    24901 tgaccttatc tttaggaaag aaccaaaaag atatactgtt gaagatacca ttccctatct
    24961 tagactctta aaaagcggga tatgtcagat tgatgagaag cattttaata agagtatcgc
    25021 ttttgaggat ataaactatc agcttgcatt agaagaagat agggatttga tttttaatca
    25081 gtttgcaaac tttcttaact cctttgatcc aagtatcagc atagagtttt cgtatatcaa
    25141 tcagcttggc agaaatgaag aaatgaaatc ggcaattcaa ataccggata aaggagatgg
    25201 ctttgacgat atacgccttg agtttcgaga aatgttgaaa agtcagattg ccaagggaaa
    25261 taacggactg aaaaaatcaa aatatgtaac ttttacagta gaagcggata atttagaaca
    25321 ggcaacatca aaactggaaa gaatggagat agatatatta tcaagcctta aaagtatggg
    25381 agtaagagca gaaagcctta acggagagga aaggctaaag atacttcacg atgttttaaa
    25441 tccgaataag acctttgaat tttcatataa ggacttaaag aaaaaggaaa gtacaaagac
    25501 atatattgct ccagatgaat ttaactttac accgtcaagg tattttaagt ttggaaagtt
    25561 tatcggagca gcaagtcatt ttcaaattct tgcaagtgag ctttcagacc gtatgcttgc
    25621 cgagtttttg gatatagatg ataacatcaa tatctctttt catataaagg caattgagca
    25681 atcagaagcc atcaagatgg taaaaagaaa aaataccgat attgataaga tgaagattga
    25741 ggaaaacaaa aaggctgtaa ggtcaggcta tgatatggac attcttccaa gtgatttaat
    25801 tacctatgga gaagatgtaa aaagcctttt aaaagatttg cagacaaggg acgagagaat
    25861 gtttgttgta accattatct ttatgaactt tgcaaggaca attcaaaagc tggataatac
    25921 catttctcaa atcagctcta ttgcgaataa acataattgt aagttaaaaa gacttgacca
    25981 ctcacaggaa cagggcttaa tcagtgtact tccacttggt gtaaataaga ttgaaattga
    26041 cagaggacta acctcatcat ctacggcagt atttatgcct tttaccacag aggagctttt
    26101 cataaactcg gtaaacagtt tgtactatgg actaaatgcc ctaagtcata acctgatcat
    26161 ggcagataga aagaaactga aaaacccgaa cggtctaatc cttggaactc cgggaagtgg
    26221 taaatccttt agtgcaaaaa gagaaatggc aaatgctatt cttacaaccg atgacgatgt
    26281 gattatctgt gatccggaag gcgagtacgg aaaccttgtg cgtcagttta aaggagaagt
    26341 tataaaggtc agcagtaagt caaaggacta tcttaatcct ttagatataa atatgaacta
    26401 tggagatggg gacgcaccac tgaaagataa ggcgaacttc attatgtcta tgcttgagct
    26461 tgtcgttggt ggtagtggtc taacagcaga agaaaagtcg gttatagata gatgccttcc
    26521 taaaatttat gaaaagtatt ttgaaaatcc cttacctgag aatatgccta ttcttcaaaa
    26581 cctgtatgat atgttaaaag gacaggaaga aaaagtcgga aaaaaactgg caacggaaat
    26641 ggagatttat gtaacaggat ctcttaatgt atttaaccat cagtccaatg tggacttaaa
    26701 taagcagctt ctttgttttg acattaagga gttaggctcg cagcttaaaa aaatcggaat
    26761 gcttgttatt caggatcagg tgtggaacaa ggtatcgcaa aacagaggaa ataaggctac
    26821 aaggtactat atagacgagt ttcacctatt gttaaaagac gagcagacag cttcctattc
    26881 cgtagagatt tggaaaagat ttcgtaagtg gggaggaatt ccgacaggca ttacacagaa
    26941 tgtcaaagac ttacttatga gtaaggaaat tgaaaatatc tttgataata cggactttgt
    27001 gctaatgctt aatcaggctt caggtgatag agaaatttta gcaaggaaac ttaaaatctc
    27061 acagccgcag ttaaaatatg taaccaattc caatgcagga gaaggacttt tgttctttgg
    27121 aaacaccatt gttcctttcc ttgataagtt cccgaaagac acaatacttt atcagaaaat
    27181 gacaaccaag cctgaagaag tgaggtaggc ttatgggaaa gaaactgaaa agggatttta
    27241 aggaaaggca aagagcaaga attgaaaagg aaacactgca aagtagtggc agcatagagt
    27301 ctgaagaaag taagctaaag cataatgatg attacagagg gaaaattgtc catgacaaag
    27361 acagatttca agataaggtg catgaaaaaa caagcaaaat aatttctgac agtgaaccgg
    27421 ttcgagggat ttccaaaaga aatacaagat atagaagttc tgaaacagga agtgtaagtc
    27481 gggaagaaat cggaaaagct gattatgcta ctgaggttaa tgacggaatc atagatagat
    27541 atgacaatga ctttagaggc agcgaatatt ttgagtcaac ctatgatgta gaggataatc
    27601 ttcatcataa agccgaagat acaaaaggct ttttaaaaaa tcaaaaagct caaaagaaaa
    27661 attataagag aaaaaactat tccgataagc tctataccag aaaaaaggac acagaggcca
    27721 aagcggaaaa ggcagacaat aaacaaggcg gaaaagaagc tatccttgat agagaaaaga
    27781 aaaacaagct ttctaaagaa caggaaacaa ttttcaagaa taaggcatct aaagtatctg
    27841 ctttatcagg cttagcaaaa ggaagtgaaa ccgtaagaga ttacttatct catggaagcg
    27901 atgaaaatca aggggtagag gcaggcgaaa agacagccga tacaagctca aaactcattc
    27961 atggcattaa gaactattcg gataagaaaa gagcccaaaa aggatatgac cttataaata
    28021 aggactataa aatcagaaag cgaaaatcca aattagagtt tcgagatgtc aaagaggaac
    28081 tgaaaaagac ggaggaatat caaaaagcaa ataactttaa gcgatttcaa aagcgaaagc
    28141 agatgaaaga ttccattaag aggcagaata agtcaaggct tagagatcgc attaaggaag
    28201 ggcttatcgg cagtcttaag ggttcaaagg aaattatatt aagaaaaacg aaaggactta
    28261 tgattatttt tataggtctt attattttgg gaactttctt cattaacttt gcagggacag
    28321 gaatgacagg ttttatgaac tctacaagta tagttcttac aacaagttat ttatcaaagc
    28381 ccaatgttct cacagaaatt aaccaacaat tttctagtat ggagcaagga ttacaagatg
    28441 agcttgaaag tgttgaagaa aatcatcccg gctatgatga gtatattgtt aataaagagg
    28501 aagatattgg tcataatacc catgaacttt tatcatacat tacttcgaga tgtggagagg
    28561 ttaaaaacat atcagaagtg aatagaattt tagatgagtt atttaagtcg atgtatcgtg
    28621 tagattacaa agaagaaatt gagataagat ataaaaccgt agctgaaaca tatactgatg
    28681 aggatggaaa cgaatatacc gaaagccatg aagaacctta cgagtacaag aaactcattg
    28741 taactcttta taaaagagaa atggatagtg ttgttcgaga agtatttcaa aattatccag
    28801 ataatgtgaa acattatgaa gcattacttg caagccttgg taatatgagt gacttttttg
    28861 gaagtggaag taatgattat tctgaaataa tcaacaatcc taattttggc aatccgggaa
    28921 tagctttcaa tgaagaaaca gttaaacgac ttttctcaga agcagaaaga catataggaa
    28981 agaggtatgt ttttggtgca aatgggccgt caaattttga ctgctcttca tttgtgtgtt
    29041 ggagttttac tcgttcaggt attaaaaata tgccaagaac aacggcttgg agaatttata
    29101 cggattactg taatcctgta agtacaggtg aagcaaaggc aggagatata atattcttta
    29161 aaaataccta taatagtgga agccctattt ctcatgtagg tatatatgcc ggaaatggga
    29221 tgatgataca tgcaggggat ccaattcaat atacttctat taactcacca tattggagag
    29281 aacattttta tgggtttgga agaccaagat aggaggatac aatttgaaaa aagaactgac
    29341 agcagtaaaa aatagaataa agaaattgaa agataaaaag gctctgattg atgaagaatt
    29401 ggagcctttg ttcattcgtg aagaagaact tgaaaacgaa gaaattattg ccatttgcag
    29461 aaagaataac attacaattt atgatcttat ggcaaaagta aatagagaaa aatcagaaat
    29521 gaaaaaggag aacggaaatg aaaaaaatga agaataaaaa ggctgcggga gtaattcttg
    29581 gagcagtgct tttgatagtg ggagtagtaa tctctttatt tgcaggtagt aagattgtat
    29641 ttgcacaggg agggttgttt acgacacttg taaatccgat agaagccgtt gctcaaatag
    29701 aagtagaagt taatgttaag tatatttttg aagatgaaaa agtctttaag gaggaaaaga
    29761 ttaaggctga aaaggggcag cttcttgaca gtggagatct tccaataatt cctgatgata
    29821 tgaaatttat agatgatttt ctattttatg aaataaaggg agacgggaaa gatgaaatta
    29881 tccgtaaagt agcaaaggtt gaggttaagg ataaggaaac gcaaacagaa aatgaaagct
    29941 caaaatctga gcaaagctcc caatcaaatg cttcaaagaa agaaaataag ggaactcaga
    30001 cagaactgag caaagataat atttccaaaa tggaaaaaga atccaaggaa cttcaggaaa
    30061 aacttgataa gttaaatcag gaaattaagg acaaggataa actaagcgat aagcaaaagg
    30121 acaaaatcaa agaccttgag gataaaatag ataagctgaa gggaaaactt gaaaagagca
    30181 aagccgataa ggacttatcg acagatatga aaaaagagat ggacaagcta actgataaga
    30241 ttaaggaact tgagaaaaaa gctaatgagg tcggtagagc tcctgttacg cataatccta
    30301 ctgtagcacc aatcaatcct atttccggga ttaaacaagg aacaggaaat gtatcaccac
    30361 aagcgtctat aaatagcagt ggcaaaggtt ctgcttcgca ggaaagtaaa ggagcaaata
    30421 caaaaaatat agatagtgat aaatcaaagg aaaaagaaaa ggaagttcgt tatccaaata
    30481 agttgacacc aaaacagcct gctaataacg gtagtcagga ttcttcattg gatggttcaa
    30541 gtaagaatgt aaataccaat aaggggattg cttcagctcc ttcaaaggca agaggagccg
    30601 ttacggaaaa taaagataat gcaaacaaag attatcctat tcaccataat gacagtaaag
    30661 ataataaaga aatggataaa tattccgctg atgcaagaca gtttgttact tttacaacta
    30721 aaaatggtaa gacttttcat ttaatcatta accatgatga gaatagcgag aatgtcatgc
    30781 ttctaactga agtatctgaa gatgatctct taaatatggt agaaaagaaa gcaccggaga
    30841 aagaggttgt taaagaagaa ccacaaaaag aagagcttaa accagttaaa aaagaagaga
    30901 gcagcaatac aggaatctac ttaattctca ttcttgtagt agcaggagca ttaggtgcag
    30961 gatattattt caaggtcatt aagaagaaag aagataagga gcttgaaggc tttgaggagg
    31021 aagatgatga tttcttttca gaggcagaag aaagtgaaaa tgaatcagat gaaacagaag
    31081 ataaagaaga tgatgaggta gagtaagttt gcacctaaaa ctatacaata tttggtgcaa
    31141 aacacagggc gggagagtaa aatctttcgc ccttttatat tgaaaacagg aggaaaaaaa
    31201 gtatgaaact tgtaattgct gaaaagccaa gtgtagcaat ctctattgca aaagtgatag
    31261 gagcaacaaa gaagaaagac ggatattatg agggaaacgg atacaaggta agctggtgtg
    31321 taggacactt gattcagatg gcaaatcctg aaagctatga tgaaaagtac gccaagtgga
    31381 atatggagga tttaccgatt atcccaagag aatataagta tgagattgca aagtccacaa
    31441 agaagcaatt tgcgattctt aaaaagctga tgaacgataa ggaaatagat attgtgataa
    31501 atgcctgcga cgcagggcgt gaaggagaag ccatcttcag gcttgtatat aatcaggcaa
    31561 attgtaaaaa gaagatgaaa cgcctttgga tttcctctat ggaagatagt gcaattagag
    31621 atggttttga taacctaaaa gatggaagtt tttatgataa tctctttgaa tcatcacaag
    31681 caagggcgat tgcggattgg attgttggaa tgaatttaag taggttgtat tcgtgcctat
    31741 ataagcaaaa ttacagtgtt ggaagagtgc agacgcctac tcttgccatg attgtaaaaa
    31801 gagatgatga gatagcaaat ttcaagaaag aaaaatatta tacagtggaa ctttctatga
    31861 atggatttac acttgcaaca gacagaattg atgatgaagt ggtagctgag cagctcttaa
    31921 atttggtagg agataagata gaaatcactg atgtcattca gaaagaaaag ataacaaaac
    31981 ctgacttacc atttgacctt acaacacttc aaagagagtg caacaaatat tttggatata
    32041 gtgcaaagca gacacttgat tatgcacaga gcctatacga gaaaaaactg attacctatc
    32101 caagaacaga tagcagatga ttaacggaag atatgattac aagtacaatc aacaacatta
    32161 ttggaaagta tgattttgat acagctcgta tcaagacagt atttaatact aaaaaggtta
    32221 cagatcatca tgcaattata ccgacagcaa gcagtatgaa tgaggactta tcttcacttc
    32281 cggaaagtga attaaaagta tatgaacttg tcttaaataa gctgcatgca agtgtaggtt
    32341 atccgctaat tgagaataca acaaaaatta tagccaaatt tgatggattt gaatttacaa
    32401 gcagtggcaa ggtgattgtt gatgaaggct ttaccaaaaa cttaaaagaa tatacaaaaa
    32461 agaaaaatga agatacagtg cttccgtatg taaagattgg tgatagtctt gatattaagg
    32521 ataaagagat aaaagaaaaa tgcacatcac cggctaaaca ttttactgaa gatcttctac
    32581 taaaggctat ggagcttgca ggaaatgacg cactggaaaa aggtgtagaa gttgagcgaa
    32641 aaggacttgg aactcctgca acaagagcag gcataattga aaatttaatt ttcaaaggtt
    32701 ttattgaaag agataaaaag aatcttattg ccacacataa aggaatcagt cttgtaacga
    32761 ttgtagaaga tacttttaaa tcagcagaaa caaccgcaaa gtgggaaatg gagttatcgg
    32821 atattgcaca gggaaaatct tcaaaggaaa attttttaga agcgattgaa aatgagataa
    32881 aaaaagtggt ttcaacttat agcaagtaag atgatactaa tttcaaagtg gaaaaaaagc
    32941 cctaaaaatg ctataatatt ttgtaggaaa agtaggaaat atggaggtgc tttatgtcgg
    33001 aagcatttat gaataatgca aaggttatgt caaaaggaca agttactatt ccaaagaaaa
    33061 tcagagaaat tttagaaatt gagaatggag attatgtaac ttttgttgta actgaaggga
    33121 aaatacaaat tgttaattca aaaactttta tagagaaaaa tatacagggc aggaaataaa
    33181 ttatatatgt cagatgcaga taggaggaat ttatgaataa agaaaagaat tctttgcaaa
    33241 atataaacat agaaaaaaac aacaattcat ttgaagaaat tgttatgatt gtagaaaatg
    33301 caaaggatcg tgcatataga agagttaatg aagagctaat attaatgtat caagaggttg
    33361 ggaaatatat tagtgaaaaa acaaaggaag catcttatgg ttcaggattc gtggataatg
    33421 tagctgaatt tttttctatt aactatcctg atttaaaagg atttaatcgc agagggcttt
    33481 acagaatgaa gcaattttac gaactgtaca aagatgacgg aaaagtgtca acgctgttga
    33541 cacaattaag ttggtctaat catttaaaaa taatgtcagg agctaaaagt agagaagaga
    33601 gagaatttta tattaactta gcaattaagg aaaatttgac tcatcgagag cttgtaagac
    33661 agatggatag tggatactat gaacgctgta tgctttcaaa tgagggaaat atgcctgcaa
    33721 tacaaagagc gaaacaggaa acacataatt tgtttatgga tagctatgta ttagaatttc
    33781 ttgatgctcc taaaattgga aatgaaagag actttcagaa gtcaattctt gaaaatttga
    33841 agaattttgt tttagaaatt ggaaaagatt tttcttttat aggtaatgag tatagagtgc
    33901 aggttggaaa tcatgactac tatattgatt tattatttta ccatagaggt ttatcctgct
    33961 tggttgcttt tgaacttaaa atcggagaat ttaagccgga atatgttggt aaaatgaacc
    34021 tatatctaga agctttagat agagaagtta agaaacaagc ggaaaaccca agtgttggag
    34081 ttattctttg tgcatcgaaa gacgatgaag tagttgagtt tgcattaagc agaagccttt
    34141 cgccaacaat ggtatctgaa tatagattaa aattgataga taaagaacta ttacaaagaa
    34201 agttaaaaga gtatacagga attgcagagc aggagataga aagatatgat gaaaaataga
    34261 taaatataac tttgtgctca aaaaatgagt gaagtagtcc atgtggaaac aataataaaa
    34321 taaaagtgtt tcaatttagt aatatactat gaaaggagat gaaaagaaat gcgtacaggt
    34381 aatgaattta acggtgttga ggatacttta tatatacctt tagctgccag aatatatgta
    34441 tctgaaaaat tcccacattt tttctatgat gaaaaggctc tatctttgaa atcgcagatt
    34501 ccaacaggcg gtatagataa caatagtacg gaatattttt atatggctag tgtttgtaga
    34561 caacagacca tagatatgaa aattaaaaaa ttccttgatg aaaataaaaa gggaaatgtg
    34621 gtattcttag gatcaggttt agagacttca tataatcgca taggaaatca aattgtaaat
    34681 ttctatcaag tagatcttcc ggatgtaata gaagtgcgaa aaagagtgct tggaaatgct
    34741 aaaaatgagc aacttatatc aggagatatg tttgacctta actggattaa ataaatagat
    34801 acttcattgc cgacactcat ttctgtagca ggtgtatatc agtattttaa cgaatataaa
    34861 attatagata tgattaaaaa aatgaaagct caatttccta atggagaatt gatatttgac
    34921 gcaacaaact ctaaaggttt ggagcttgct aataaatatg tgaagaaaac gggaaataaa
    34981 aatgcacaaa tgtattttag tgttgataat cctaaagatt tagcagataa gacaaaaaca
    35041 atactattgg aagttgatgg attttttcat ggagcattga aggattgtca gggattaaaa
    35101 ctaatgacga ggatatatat gtattttgca gataagttgc atcgaacagt ggttatacat
    35161 ttgaagttta attaaattct attcaattgg tttttattac ttgtattcaa cgtataatat
    35221 atagaatcaa aaggtgatta gagtaaaatc taaccgcctt ttttgtttgt aaaaaagaag
    35281 gaggaaatat gcgaataaat gattttcata acgttttgga gcttgtaaaa caggatattc
    35341 tgcaaagtga agcagaatac ctgaagctct taaaggttgt cggaaacaat cagagatacg
    35401 actttagaag tcagttaagt atctatgata gaaatcctga agcgacagcc tgtgccaagt
    35461 ttgattattg gagggagcga tttaaccgta ctgttgtacg agggcaaaag ggtatcccca
    35521 ttttagagga ctacggcaca tataaaaaag tggactatat ctttgatata gagtagacag
    35581 tttcaagaaa cagagatgtc aatgaagtaa atctttggag atttgataaa gaagtccata
    35641 gagatgtctt aaaggaaatg ataaaagctg agggatatga agaaagcgaa agtaccttag
    35701 aaaatatctt ttctttaagc agactttatg gcgatgaaaa gatagacagt cttatgaatg
    35761 agcttagaat agctgatgaa gatagaatat cctttacgaa gtttgtgagg gattcagtaa
    35821 gttatgcggt agcttcaagg tttaagttag attatccgat gaataataag cttctaaagg
    35881 aaagctttac aatgcttgat agtatttccc ttatgagctt aggtgaaact gtatcggata
    35941 ttagcggaaa gattattgat gcaatcattc aaaaaagcaa aaaactggag cttcaaaaag
    36001 aagttttaag aggaaaagaa gcagaatata ataaaataaa agaagaatta gaggaggtag
    36061 aagaaaatgt acttcgacga gatgatcagg aaagaattag tgaaaacgag cgaattttcc
    36121 gaaatgaaga gtacggacga gataatagag aaaatcaagg agaatacgct gaatcagtta
    36181 gaggaagaga tggactttat gagggaatat ccgaatccca catacgcagt gatgaggctg
    36241 gagtttcttt caaacagcga ggagcagagt cacttcgaga tgttattgga tctatacaag
    36301 gagaagaagc tgaccaaata cctaatggat attcagaaac aggcgataga gtttatgaga
    36361 gcagagaagc cgaaactgat gatggcttgg aagatagagg acgagaacca tccgcagtac
    36421 aaagcgatga tttcagccct caaagaaatg acaatcaggg aagtagtgga aatctaaaag
    36481 agaatacgga taaagagata agagaagctg acagggcttc tttttcttta cctgaaaaca
    36541 gttcaggaca aattaaattt acgatacctc ttacacaaaa tgatattgat agtattcttg
    36601 taaacggtgg aaaccacgag ggtggcagac ttcctatcat tgctgaattt tccaaaggaa
    36661 aaacagtaga cgaattagga gaatacctta aagatacctt caaaggcgga aacggtttac
    36721 ttcttaatga agcagaagta tcttcctggt attcggataa aggcattcat ttagcttatg
    36781 gaacttcagc aagagaagat atgacgcaaa ttttaagctg gaatgatgct gcaagaagaa
    36841 taaatgagct tttgggaaat ggagagtttg ccacaaatgt agagctatta gaagcacagg
    36901 actatgaaag agatagagtt tcagagtcgc tatggtatct atatcacgat ttaagcgaag
    36961 aaggaagagc acagggctat tttgacttta tagaaagagg tggtggcttt ccgaaagaaa
    37021 caagacagtt atcggaagct cttaaaaatc ccgactatct gaaagatgtt atttctgaat
    37081 acagtcgctt tttgaaagga tataaagaaa acaaagatgt actaaggttt cactatcaca
    37141 aagtagacag cctttataag aacttacagg agcttgcact tccgagaaag gaatacactt
    37201 ctaaccttac tgaacttcca caggtacatg gctttattac agaagatgaa gtccttgcta
    37261 cgatttcaag aggaagcggc ttcgatcaag gaaaagagag gattacaaaa tattttaaag
    37321 aaagccacac tttgcaggaa aaagcgaatt tcctaaaaga tgagtatgga atcggaggtc
    37381 attctcatgc tgtttcaggg gcaaagggaa gtgatgaatg gcacgatgca aaggggctta
    37441 aattacagaa gaatcattgt aacgatgttt ttcttacatg gtcaaatgta gcaaagcata
    37501 tagatgagct tatttctaaa aatctttatc ttaaagaaaa taaaattgaa agtaaggcag
    37561 aaatagaaga acaaaaagag ccaagttatt actctaaaga cgatccatat aatctaatga
    37621 ctgatgaaat gcttgagcga gtgcctgagc tttatgcaca agaggatgta gctttagcgg
    37681 ataaacaggt tcatgcagca tacattattc catttagaag taactggact tggtatatga
    37741 cagagtacga tagagaaagt aaagatgctt ttgggcttgt tttaggtatt gaaccggaat
    37801 ggggatattt taatcttgag gagctaaagg aactaaatgc ccagaggctt gttttagaag
    37861 attttccaaa gacctttaga gaacttaaaa acagtgaact taaaaagcag atggatgagc
    37921 aggagcttca tcaagtattt aatggagagc taagttttga ggagaataat acagagcttg
    37981 aattacctga agaagtagaa gaaagcatac aagcagaatc ttttcaggct accttatttg
    38041 attatctaaa ggaaagagaa gaagtagagc ttaatgaaaa agaggacagc ctttcagatg
    38101 agtttgcggt taaagaaggc gatactgtct attttaatca tgaggtgtac aaagtaagag
    38161 agatttttaa aaatcaaatc actggaagaa atgatttgtg gcttgatcct gtaagacaag
    38221 gtaatcatca aataccgatt gtaggcttta cagataatga ggatttatta agacaaataa
    38281 gtcttgaaag acctgaattt atcatcggtg atgaagtgaa gtacaaggga aaagactata
    38341 ccattacaag atttgatgat atgggaaata acctaaagac agtaacagtc aaggatgata
    38401 ccgaatatct tggtggtatg attacaggct ccgatgtaat tccttatcgc caagaaagtg
    38461 agcttgataa aatctttgaa aatctgacct atgaaaaaga tgagctttac aacattgcag
    38521 taagaataga tgagatagcc tatgattttg atccttatga ctatgcggat tccgtaggaa
    38581 cagaatcaga ggaaaggctg aataatatca accaaatcta tggtgattta caagcgggaa
    38641 atatttcagc gtatataagt ggtctgaatg agatgattga agaagatgtt gaagatgcgg
    38701 aaagtatcaa gcaagtctta actaaattgg aagaaaaaaa gattgatatt cagcctaaac
    38761 aagaagtatt aaacttcaag attacagaag aaacgcttcc tcaaaggtta tctccaagtg
    38821 agaggttaaa taataacctt gaagcaatat ctatgcttaa cagagtggaa agcggagaac
    38881 gagagcttga tattacagct caggaagttt tagcgaaata tgtaggctgg ggaggacttt
    38941 ccgatgtctt tgatgaaagt aaggatggac agtggaaaga ggcaagagct ttcttaaagg
    39001 aaaatctatc gtcatcagaa tatgaagctg caagagaatc aaccctaacg agcttttaca
    39061 caccaaaaac tgtcatagac ggaatatata agacgctttc cagtatggga tttaaacagg
    39121 gaaatatcct tgaaccatca atgggtattg ggaactttat aggcaatata cctgatgaaa
    39181 tgagtaagtc aaagttttat ggcatagagc ttgattcggt aagcggtcgt attggaaaac
    39241 tgctgtatcc ggaaagtgaa gtacaggtaa agggactgga agaaacggga ttctccaata
    39301 atttctttga tgttgcaatc ggaaatgttc catttggaga gtacaaggta aatgacagag
    39361 aatataaccg caataacttt cttatccacg attatttctt tgccaagtcc atagataaag
    39421 taagaaacgg cggtgttatc gcctttatta catcttcagg aacaatggat aaaaaagacg
    39481 aaagtgtaag aaggtatctt gcagcaagag ctgaattttt aggggcaatc agacttccaa
    39541 acgatacctt taagggtgtt gccggcacag aagtaacttc ggatattatc ttcctaaaga
    39601 aaagagatag cgtattggag cgagatgaag attggataca ccttgcggaa gatgaaaacg
    39661 ggcttatata taacaaatac tttgtcgatc attcggagca ggtacttggt tctatgcgtg
    39721 aagtaagcgg aagatttggg aaaactctaa cttgtgaacc gatagcttat ttagggcaag
    39781 agaataacat ggcttcatta aaggatcgta tcgagattgc aggagaaaga atttcaaaag
    39841 atgccaagta tgaagaaata gagcttttag atgatgaaat agcctctatc cctgcaaccg
    39901 atgatgtaaa gaacttctcg tataccttaa ttgatgatga agtctattac agagaaaact
    39961 cactctttat caaaaaggaa gtatcagaca agaataaaga aaaaatcaag gattacctaa
    40021 aactgaatgc tgtcttaaaa gatgtgattt acaagcagaa ggaagatttt agtgaggaag
    40081 aaattaaggc ttcacaggaa aaactaaatg aagtatatga caacttttca aagaagcatg
    40141 gttttgtaaa taatttaagt aataccagag cattgaaaga ggatagtaac tttccgcttg
    40201 tttcctccat agaaatcctt gatgaagaag aaaatttcaa ggcaaaggga gatattttct
    40261 caaaaagaac cattacaaaa gcgaaagtca tagaccatgt ggatacttct ttagaagctc
    40321 ttgttttatc ggtatctgaa aaaggttatg tggactttga ctatatggga agtcttatag
    40381 gaaaggacag accgacttta attgaggagc ttcgagggga aatctaccta aatattagag
    40441 aagagcaaaa cttttataga ccactttcct ttaacttgga ggatggcgat ttaccttttt
    40501 cctgtgcaaa tggcagcaat tcctataaat atggctatgt aacaaaggat gaatacctaa
    40561 gtgggaatat cagggataag attgctatag tcgatagtta tctatcaaaa ttaagacaaa
    40621 cggaaagaga actacctcat cttggctatg aagaagatgg aaaagaaaaa gagctgataa
    40681 gctatgaaat gaaccgttta gaatatcaaa aagcagagct tatcaaagtt cttccaaagg
    40741 aattagaagc aagtgaaatc aatgtaaggc ttggtgcaac ttggataccg attaaagata
    40801 ttgagaaatt tctctttgaa actctaaaaa ctccggggta tgcaagatgg gatattaagg
    40861 ttaaattttc aaaccttaca agcgagtgga atatagaagg aaaaagcaaa gatagaggaa
    40921 atgaccttgc tgaaatgacc tatggtacaa gtagagtcag tgcctataag ctcattgaag
    40981 atgctttaaa ccttaaagaa acaaagatat ttgaccagat tgtaaatccg gatggttcaa
    41041 agacttcagt tttaaataaa aaagaaacca tgcttgcagg acaaaagcaa gagctattaa
    41101 aagaagaatt taaaaactgg atatttaacg atcaggaaag aagaaaccgc cttgtaaaac
    41161 tgtataatga gcgttttaac tccatccgaa acagagaata tgatggaagt aacctttcat
    41221 ttgagggaat gaatacaaag attgatttaa gacctcatca aagaaatgct atagcaagaa
    41281 gcctttatgg aggaaataca ttgcttgccc atgtagtagg cagtggaaag acctttgaga
    41341 tggtcgcttc tgcaatggaa agtaaaaggc ttggaatgtg cagtaagtcc ctgtttgttg
    41401 tacccaatca cttaacaggg caaatcggtc gtgagtttat gcagctatat ccgtcggcta
    41461 atattatagt agctgataaa aaagactttg aaccgaaaag cagaaagcga tttatcggta
    41521 agattgcaac gggggaatac gatgcggttg ttatcggaca tacgcagttt gaaaaaatcc
    41581 ctatgagtaa ggaatatcag gagaagcaca tccaagatca gattgatgaa atcgtaaact
    41641 atgtagaaga atacaagcat gatagaaacc aaaactttac ggtaaaacag cttgaaaaga
    41701 caaagaaaaa actagaaaca aggcttgaga aattaaatga tgattttaag aaagacgatg
    41761 tgattacctt tgaggaatta ggagttgata agctctttgt tgacgaggca cataattaca
    41821 agaaccttta tctctatacc aaaatgagaa atgttgcagg tatcggacag tcagaagcct
    41881 ttaagtcttc tgatatgttt atgaagtgcc gttacatgga tgaaatgaca ggaggaaaag
    41941 gcattgtatt tgccacagga acgcctgtaa gtaactctat gacggagctt tataccatgc
    42001 aaaggtatct tcagtatgag agcctaaaga aaaatcactt ggagcatttt gattcttggg
    42061 cttccacttt tggagaaaca caaagctcct ttgaattatc gcctgaaggt acaggatata
    42121 gggtgaaaac aagattttca aagttctata acttgcctga gcttatgagt atgtttaagg
    42181 aagttgctga tattcagact gcggatatgc ttaaccttcc tacacctgaa gctaactatg
    42241 aagttattaa aacggagcct tctgaagaac aaaaggaaat tctaaagagc ctttctgaaa
    42301 gagcagatga tgtcagaaat agagttgtag agcctgatga agataatatg cttaaaatta
    42361 ccaatgacgg taagaaactt gccttagatc agcgtttgat aaatccccta cttcctgata
    42421 atcccgaaag taaagtaaat gtgtgcgtga aaaatgtatt tgctatttgg gataagacaa
    42481 aagagagtag atcaacacag ctactttttt ctgatatgtc tactccaaaa ggagatggag
    42541 aatttaacat ctatgatgac attagagaaa aacttgtagc aatgggcata ccgaaagaag
    42601 aaattgcctt tattcacgaa gctaattccg ataagcaaaa agatgaactc tttgcaaagg
    42661 taagaaaagg cgaagttcgt atcttaatgg gttcaactca aaagatggga gccggaacga
    42721 atgtgcaaaa taagctgatt gcacttcatg atttggatgt accttggcgt cctgccgatt
    42781 tggagcaacg ctctggaaga attgttcgtc aaggtaatga aaacaatgaa gtaaatatct
    42841 atcgttatat tacagagaat acctttgatg cctacctctg gcagacgata gagaacaagc
    42901 aaaagttcat ttctcagatt atgacaagta agacgcctgt tcgtgtggca gaagatgtag
    42961 acgagagctc gcttaattat gctgagatga aagcactggc tactggcgat ccgaaaatta
    43021 aggaaaagat ggacttggat aatgaagtta ccaaacttaa aatgcttgaa gcaaactata
    43081 agtccaatgg ctatagatta gaggataaga tagctaaaac ctatcctgaa gaaatagcca
    43141 ggactgaaaa gctaatagaa gcagttaaga aagatataac caatgttgaa ccacaaggaa
    43201 ctggagaaaa taagtttatt tcgatcacta ttggtggtga aaaaatctta gataaaaagc
    43261 ttgctggcga aaaacttctt gaagctatta agacagttaa aatcaatgaa agtaaggtga
    43321 ttggtcagta tcgaggtatg gatttagaag tgagttataa cttctttaca aatgagcata
    43381 actttagctt aaatggtgct acaaagcata caggtaaact cggtacaagt gcagatggta
    43441 attttacgag acttgataat gcaatcgaga atatgccaga aaaactaaat agacttgaag
    43501 aaaagcttat agctactaaa gagcaatttg aaaacgccaa agaggaatta aaaaagcctt
    43561 ttgaaaaggc agacgagcta aagactaaag tgcttagatt agcagaatta aataagcttc
    43621 ttgatatggg agaagtagac gaaaaagaaa atcctaatcc acttcttgaa gatgtaaaac
    43681 gagctattgt agatttctgt aagagtgaat atgaggacaa tagttatacc tatgaaaact
    43741 tcaataatct atttcctgac cttgctcata ttggaattgc ctatacaact acaccagatg
    43801 aaaagcatga gatacagtat gaaattagct tagaagattt cacatctact caatatatca
    43861 atggtgagcc tattaccaag attgactatc taaaagacct tggaagtgaa gaaaaagcat
    43921 tagagttttt aaaacaagaa atggaatatg gagactttgg cgagtttgta tccattaatg
    43981 ataatgacct taaaaaagct ctaggacttg aaagagacga ttatggtaat atctatgatc
    44041 cacttgcaaa agacttggat aatgatggtg taccagatag atatgataat gactttagag
    44101 atagtgatta ctttgaaaca acctatgatg tagaagataa tcttcatgta aaatctgaaa
    44161 gcacagaaaa ggtatcggag aaaccatcaa tcttaagaca gattaagtca tatcagtctg
    44221 aagaaaaaca aactgaagca agagaaaata aatcaaaaga acatgatgaa cgttaagggg
    44281 cttatatcaa gctccttttc gctttttagt agaaaatatg gaggtgtatg atgaactaca
    44341 aagaaatcag aaacacatta gaacaaatgg caaatgaaag ccatgaagac tttgcaaagg
    44401 cacttataag ctttgaaaaa ggtataaatg acaaggaagc attggataag ctatatcaag
    44461 agtatatgga aaatgatagt atgagcctac ttaatgatga gtttgattac ttgattgagg
    44521 agcttagaga aaatggacag attaaagata ctgcagcaat cgaaaaagaa gataatgacc
    44581 ttgtaaacat tgttggaaat atcgtaggtg aagtagatgt tgtagaaaga gaaaataaga
    44641 atggcgaagt ctttaaagta gttaatttct ctgttgcatc taaagatgat gatggaagca
    44701 agacgtacac aaactgctcg gcttatggag ataaagtaga aattccaaag gactttaaac
    44761 aaggcgattt cgtaaaacta tttggtcagc ttagaacttc tattgatgat aatggcaagg
    44821 aatatagcaa tgttagaatc ctatcttcaa agctcttaaa agcaaaagaa cagatgaaga
    44881 accaggaaga aaagaaagaa tctgttcttg gagcgattaa gaaatataag gctgaagaga
    44941 aggctaagcc aacagagaaa aaagaagctt taaaagaaac tgaaagataa gatgtgtcgg
    45001 tgtggtcttc ggactgcacc gattattttt tttgtctttt tgtgtatagc aacagtttgt
    45061 tatttgtgat ataatttatg tataaaaaat ccaagtttat ggaataagga gaaataataa
    45121 tgaaatttaa ctacaatggt ctttggaaag tattgataga taagaatatg aagaaaaaag
    45181 atttaattga tagaacaggt atatctccaa cgacaatatc taagatggtt agaggagaag
    45241 cagtctcgtt atctgtaata ggaaaaattt gtgaagagct tggaacagat attggagatt
    45301 taattcatat tgaaaaaggt atcgaggagg ataaataaat gcaaagtaca tataatgcac
    45361 ttgaatataa taagttaatt agttttattt ggtctgtagc agatgattgc cttagagatg
    45421 tttatgtaag aggaaagtat agagatgtaa tccttccgat gactgtaata agacgattcg
    45481 attctatcat tgagccagaa aaagcaaata taatgaaagt taaggaaatg gcggagaaac
    45541 aaggctggga tgttgcaaaa acattagata cagcagtggg gttgccattt tataatacat
    45601 ctaatttttg cttaaaagac ttgaagcatg agactaacag acagaatttg aaaaagaatt
    45661 tcgaagaata tttaaatggc ttttcagaga atgtaaaaga gattcttcaa aagtttgatt
    45721 ttaataacca gctaactaag atgactgatg ctggtatttt gggctctgta atcgaaaaat
    45781 ttacatcaag tgaattgaat ttaagtcctt atgatgagaa aaactcgaac ggtgaaataa
    45841 tcaaaaaagg cttagataat catgctatgg gaacactgtt tgaagagatt attagaaaat
    45901 ttaatgaaga aaataatgaa gaagcgggag aacacttcac gcctcgtgat gtaattgagt
    45961 tgatggcgga tattactatg tatcctataa tggataagat taaggatggg acttactcaa
    46021 tctatgatgg tgcatgtggt actcttggta tgggaactgt agcagaggaa agattgaaag
    46081 acttcgcaaa agaaaacgga aaagaagtat ctatccattt aattggacaa gaagtcaatc
    46141 ctgaaacata cgcaatttct aaggcggatt tgcttattaa aggtggagat acagactcaa
    46201 ataatgttca ttatggttca actctatctg aagacaagac atctggtcag cattttgatt
    46261 ttatgctatc caatcctcca tatggcaaat cgtggaaaat ggatttagca attttgggaa
    46321 ttggagaaga caaggattta aagaaaaata taattgataa gcgatttgtt agaaattata
    46381 aggaacaaaa tgattttaga atgattcctg atgtaagtga tgggcaattg cttttcttat
    46441 tgaacaatat ttcgaagatg aaagaaactg aattaggctc acgcattgtt gaagttcata
    46501 atggttcggc tctttttact ggtgatgcag gaaatggtgc aagtaatgct agaagattta
    46561 tgattgaaga agatctcata gaagctatta tccagttacc agaaaatatg ttttataaca
    46621 caggaataac tacttatata tgggtgttgt ctaataggaa agaagaaaga agaaaaggca
    46681 aaatccaatt aattaatgct aatggtataa aaacatcatt aagaaaaaat atgggaaaga
    46741 aaaactgtga gttctctgag gctgatagaa gattcattct aaatgaatat ctaaagtttg
    46801 aagaaaatga gtattccaaa atattttcta atgaggaatt tggatatttt aaagttactg
    46861 ttgaacgtcc attaagacaa gcagttttat gcaattatga aaatataaat gaagtagaga
    46921 aagaacttga aaaaattgga gcaactacag gaaaaataga taaaaagctg attgctgaaa
    46981 gttttgtaaa aggaactgct ggttctatca aagagcttga aaagaaagaa aatataaaag
    47041 catatttaga agtacttaga gaaatggaaa gttctgaaaa gtatttagat tatgaggctt
    47101 ttgaaaaagc ttttaataag aatttgaaaa acaaaaatat aaaaggtgct agttttagta
    47161 aacttgtatc tacgggacta ttagcaaata tgattattag agatgaggaa gctgaagtgc
    47221 aaactgattc caaaggtaat ttaattgtag atcctgaatt aagagacacg gaaagcatcc
    47281 ctatgacatt tgtaggtgga attgatgagt ttataaggca agaggtctta ccttatcatg
    47341 aagatgcctt tgttgatgaa agtaagacgc agataggata tgaaattaac tttactaagt
    47401 acttttacaa agccaagaaa cttgaaaatg tggaggatat tgtttgtcgc attaaggaat
    47461 tagaaaaaag gtcagacgga atgatggaaa ctgtattgga gggtctctat gaataagtat
    47521 gagagatata gagatactgg gctaatatgg ataaataaag ttcctaaaaa atggaatcta
    47581 caaaaaatta atgcagtttt tgatgagaga agagaaaaag tatcagataa agattatgaa
    47641 gcactttctg ttacaaaaaa tggaatattt aagcaactag ataatgtagc taaaacaata
    47701 gacggtgaca atagaaaaaa agtgaaaatt aatgattttg ttataaatag caggtctgat
    47761 aggaaaggat catcaggatt aagcagattt gatgggtctg tttctttaat aaatactgtt
    47821 ttaaagataa agaaagagta tccacgatat atgcactatt tgttgaaatc tgttccgttc
    47881 caagaagaat tttatagaaa tggaaagggt attgtagcag atttatggag tacaaacttt
    47941 cagtcaatga aaagtattat tttaccaata cctccaattg aagaacaagt tcaaattgca
    48001 aactatcttg attggaaaat caatgagata aataggttaa ttcaaataga aaaggagaag
    48061 ataaaagagt tagaaacatt aagatttaat gctatttccg aatttgtatt aagaggaatt
    48121 ggtacgcaga attataaaaa gagtagtata aactggctag atgaaatccc aagtcattgg
    48181 aatgaggtat caattagatg gtgtgtaaat attattagag gtaattcaac ctttacaaaa
    48241 gatgatttgc agaatagagg aaaatatgtt ggattacaat atggaaaagt ttataaaacc
    48301 gagataatag attcagagtt tgatttttat gttagtgata aattttataa acctgctcaa
    48361 gttgtaaata ggaatgacat tatcatagtg tccacttcag agacagtgga agacttagga
    48421 catacatcat tttacgatag agatgatatt ggacttattg gtggagaaca aatattatta
    48481 aaaccatcaa acaatattaa ttctaaatat ctcttctatt tatctaaaat tttccgaatg
    48541 cagttgcaat tatgtgctac aggaataaag gtttacagat ttaaaattag cgatttgaaa
    48601 caaatatatg tacctttgcc accaatgaaa gaacaagaaa aaatagtttc aaatatagaa
    48661 ttaaagctgg aacaaataga tgaaagagtg aagaataatt atgcttttat taaggagtta
    48721 gagttactta aacagtcact aatatcagaa gttgtaacag gtaaaattga tgttagaaat
    48781 attgatattt ctgaatatga aaaagtaact attatagagg atgaaataga agaatttgat
    48841 gaagtaggtg gtgaagaaga tgggaattag agatacaaag atggaagccg aacttgaaaa
    48901 taatatcatt gagtatctta cgagagagca aaagtatggt gcttatcagt atattactcc
    48961 agatgaaatg aaactttcat ataatcgaaa gtatgccttt gatgaaatac gattactaac
    49021 attcataaag gaatcacaac caggagaatt cgatatactt agattagata cagaagacgg
    49081 aaaggataag ttttttaaac agcttgatgt atctataaag caaaagggaa ttgtggctgt
    49141 tttaaaaaat ggaataaaat gttatccgtc ttccggaaca attatctttt atcacgcttt
    49201 ggatcccaaa agaccgagtt cgtatgatga atttagggag aatattttta cagttacgaa
    49261 tcaactgaca tattctgata aaaatagagg tttagagctt gatttagcta tttttgtaaa
    49321 tggtctgcct attgtaacaa tggaacttaa gagtagagct tccagtaatg gttggacata
    49381 taaagatgct gaggaacaat ataagaatga tagagatcca aaggaaacga tatttagctt
    49441 taagaggtgc attgcacatc ttgccgtaga tgaaaatttt atctcattta caacaagatt
    49501 agatggtaaa aatacaagat ttatgccatt taataaaggc accattgatg gtggctctgg
    49561 caatcctatt aatccagatg gaacaatgac ggattattta tggaaaaact ttttagacaa
    49621 agaaatttta acaagcttaa ttagggattt tgcttatatt tcagtagata aagttaagaa
    49681 aagcgagaca ttaattttcc ctagatatca tcaatatagg gttgtaacta ggcttgtaga
    49741 tgatgtacag aaaaatggag ttggaaatag atacctaatt cagcatagtg caggtagtgg
    49801 taagagtaat tctataacat ggcttgcgta tcgcttagtt gaggtggatt ataataacca
    49861 aaaggcgttt gattcggtaa tagttgttac ggataggttg aatttagata aacagataaa
    49921 tgacaatatc aggaagttta tagatgagaa gagcgttgta ggtcatgcta attcttcaac
    49981 agatttgaag aacctactag ttgatggcaa gaaaatcatt attactacag tacagaaatt
    50041 cccttatttg cttgaaaaaa taggtactga tttaaagggt aagaattttg ctattattat
    50101 tgacgaagct cactcttctc aaagtggtcg tgcagcagct tcattaaata tggcggtatc
    50161 aggaagtctg agtaacgatg atgaatttga aattgaagat aaactgaacg aatttattga
    50221 agctagaaag atgcctgaaa atgctagttt ctttgcattt actgctacac ctaaagcgaa
    50281 aacaattcaa atgtttggaa atgtatttga cctgtattct atgaaacaag ctattgaaga
    50341 agggtttatt cttgatgtac taaagaatta tacacattat gaaaactact ataagattta
    50401 taaaactata gaggataatc caaactttga taaaaagaag gctcaaaaga aaattagaaa
    50461 ttttgttgaa ggacaggaat ttccaataag agaaaaagct gaggttatgg taaatcattt
    50521 ccttacaaat acagtaaata agatcaatgg taaagctaaa gctatgatta taactcaaag
    50581 tattttaaga gctattgagt attattacat agttagtgaa ttattaaata actctaatac
    50641 agggtatgaa gctttagttg cattttctgg ggagaaggaa tacaagggaa aagtagtgac
    50701 agaagccagc ttgaatggtt tttccgataa agagacacca gaaaaattta agcaagataa
    50761 atacaagttc ttaattgttg ctgacaaata tcaaactgga tatgatgaac cacttctaca
    50821 tactatgtat gtagataaag ttttgaatga tgttaaagca gtacaaacat tgtcgagact
    50881 aaatagaagt gcaaaatata agatcgatac ttgtgtaatt gattttgcta atgagccaga
    50941 acatatacta gaagcattcc aaccatacta caaggaaaca aaattggaag gagaaacaga
    51001 tcctaataaa ttaaacaatt tgctttctat gcttgatagt aagtatatat atgaagaaga
    51061 tgaggttgat aggcttgttg atttattctt aaagaatagt cctagaagtt ttatagacag
    51121 cattgtcgat aaatctgtag aaagatataa agttttaagt gaggaagaac aagtagagtt
    51181 caagagtgga gtcaaatcct ttataaggac atataatttc ttggcttcca ttttacctat
    51241 tggacaagtt gattgggaaa agaaagttat tttctttgaa cagttgattc atagattgcc
    51301 tacaccagaa ggtgaggatt tatctgaggg aattctagaa tcagtggatc ttgaaagcta
    51361 taggctggaa aagaaaaata caatagatat tatcctagaa gatgaggatg gcattgttga
    51421 aggtcttggt attagtgctg gtaaaaagaa tgaagttgaa ttagattctt tggaaaatat
    51481 tgtctctact ttcaatgaca tttttggaaa tattgattgg caagacaaag acaatgttgc
    51541 aagacaaatt aaagagttgc cagagatggt aatgaagaac gaaaagttca aaaatgctct
    51601 aaaaaattca gatattgaaa atatcaagag ggaatatcac tcagcactga aagaagtttt
    51661 cagaattata atggtcgata acatggaact ttttgggcaa tggacaaata attcgaactt
    51721 tagtaaatgg ctaaacgata cgatttttga tgagattatg aagaaaaata aaaggtaaag
    51781 gtggcgatta atttgggtag tatatcagga gttactagaa gagatattat tgatttgttt
    51841 aaaaacggaa taacagaaga taattggcta acagaagaaa ctatatatta cccttattat
    51901 ggtcgctttg atatcgtaga ttttctcaaa agattgtata agctagatac ttggaaaagt
    51961 ggagattcta gactaaaaaa tgcagagcaa gaaattacga tgcatacacg taatggcgat
    52021 tatccagatg attggatttt tgctgatgaa aggtttcact tacttgatgg tgaagatagt
    52081 gttttattgg gctttctctg tgaagttttt caccctgaag taagagatga aaataaagaa
    52141 tggaagaaat atttagaaag aataaatagt ctgttacgtg aagatggata cgaactaatt
    52201 gcttctagta ggctttctgg gagagatgtc ttcacctgga gagtatatat taagaagcca
    52261 gatatgtata ttcctttttc tgaaagaaat aagtcattga tagtaggtag aaaaataaat
    52321 tttaaacttc ctaatgcagt gagacatcag ctttttaagg tgatggatga gtatgatgaa
    52381 atattttact taactgatga aaccaattgg aattatacaa aatatagtag tgattatgtt
    52441 ttagaagata ttaataaatt ttatgtacca aaacattatg ttgatagtaa tcttgctgaa
    52501 ataaaaaagt ttaaggattt tcaagaaggc acttctccat tcgtaatttt tgatgtcatt
    52561 gaaagcttta ataggcatac tacaaattca gaaggatttg aaaatgaaat taattctatt
    52621 tttaatttga ataatattaa tgtagaactt agaagaggtg agatacattc ttctactaat
    52681 aagacattat cattagatcc ttctgtaaaa attaatgaaa taggcataga agagttaatt
    52741 agagctgcag aagatttata tagaaaaggt aaatactcgt atgctgttga aaagatttgg
    52801 gatgcttttg aaaggattaa aacgtactat tatcctgaat tagataaaaa gaaatcagca
    52861 aataagataa ttgatgaact aagtaatggg aatgacagca ttaaaagtat gtttcaagct
    52921 gaatttaaat atttaacaga tattggtaat tcgtatcgca taagacatca tgaaaaaaac
    52981 aaaatagata ttaccgaaga tttacactat gaatattttt ataagaggtg tttagcttta
    53041 atatcagttt tagtaaaaaa aatataataa acgtgaggta aaagatggtt gatttcaaaa
    53101 agaaggttgc tttaaaaagt aaagcgaaag ttacaaatcc aattgattta tataatactc
    53161 ttgatagaaa gagtattgct gggccgcttc gacctgttca agaatatgtt ttaaatgaat
    53221 ggtacgagaa tagaagaaat gaaagagatt taattgttaa acttcatacg ggcgaaggga
    53281 aaaccttgat aggtttgcta atattacaat catcaattaa cataggtgaa ggaccatgta
    53341 tatatgtttg ccctaatata tatttggtac gacaagtgtg tgctgaagct aataaatttg
    53401 gtattccctt ttgtgagata gaacaaaata atgttttacc aaatgaattt ttatcgggtg
    53461 agaaaatttt aataacacat gcacataaaa tatttaatgg aaagtcaatt tttggaatag
    53521 gaaataaatg tgttaatgca ggaacgatta ttctggatga ttctcatgct tgtatagatg
    53581 tattaaaaga tgcatttact attactatcg ggaaaaaaga aaaagagaat gtatataaca
    53641 agatattaac attattttca gaagatttaa tagagcaggg ggagggaagt ttcttagata
    53701 tcaaatctgg tgaatatgaa acattcatga ctgttccata ttgggcatgg attaataaaa
    53761 aatcagaaat tctaaaaata ctttcagatg agtcagcaag tgatgaaatc aaatttgctt
    53821 ggccgctaat gaaagataaa ataatagagt attcatgttt tatatctggt aataaaattg
    53881 aaataactcc atataatgtt agtgtagagc aatttcgaac attttcatca gcgaaacgaa
    53941 gaatattaat gtctgcaaca acacaagaag atatattttt tgtaaaaggg cttgatttct
    54001 ctactaatgc tgttgcaaat ccaattaaat atccaaaatc acgatggtct ggagaaaaaa
    54061 tggttttaat gccgtcgttg atagatgaag aatgtgatag agatttagtt gccacacaat
    54121 ttgctgcact gacgaatgca ccttttggtg ttgtagcaat cgtaccgaat acaaaaaggg
    54181 cagtatatta tgaaaatatt ggggcaaatt tccccaaaaa taataaagaa ttattcgaag
    54241 ttattgatga cttgagaaag ggaaaattta gtaatactgt agttataaat aacaggtatg
    54301 atggtattga tttacctgat gaaagttgta gagttttggt aatagattcg ttgccttatt
    54361 tgaatagcta ttttgataaa tacgaagaga aatgctgccc aaatagtgaa ataataaata
    54421 aaaaaattgc tcaaaaaata gagcaaggta taggtagagc ggttcgtggt gaaaaagatt
    54481 attgtgcaat tatcgtaatt ggttcagata ttgaaaaatt tatgcgaggt attttaacga
    54541 gaaaatattt ttcgtctcaa acacaaaaac aaattgaaat tggttttgaa gttgctaaaa
    54601 tggcaaaaga agagattttg caggatgatc cttcaatgaa acaaatattt tctttgataa
    54661 agcaaatatt aaatagagat gagggttgga aagaatatta tgctagcgaa atgaatgaaa
    54721 tcgaagatgg ggttttagat acttcgattt atgaaagata tgctgcagag actaaattag
    54781 aaaaactatt ttctgatgga gaatatgaaa aagcatctga agaaacgcag aagtttattg
    54841 ataagtttat acatgatgac ttagagagag gttggtatct agaacagaag gcaagataca
    54901 ctttcatgta ctctcaagaa gaatcagctc atttacaaaa agttgcattc caaaaaaact
    54961 ctcaattgtt aaaacctaac agtggaataa tttatgataa agtttcattt ttaaatgaga
    55021 atcgactaat tagatttaga aaatatatta gtaaatttaa cgatttcgat gagtttagtc
    55081 tacatttaaa cgaagtgtta aataactttt catttggaat agatgccgat aaatttgaat
    55141 ctgcattaaa aagcatagga gaaatgctag gatacattag tcaacgtcca gatcaagaga
    55201 taagaaaagg accagataac ttgtggtgtg cctcaaataa aaaatatgcg atttttgaat
    55261 gtaaaagtga agtagatgaa aatcgtggtg caataaaaaa atctgaggct gggcaattta
    55321 ataatcattg tggttggttt aaaacggaat atgatgaata tgttgatgta ttgcgtgtta
    55381 ttgtcattcc tacaaaaaaa cttgcccgtg atgcagattt tacagatgaa gtttttgtta
    55441 tgaggaagaa tggggtgaag aagttaaaag ataacattaa aaactttatg aaagagataa
    55501 agaaatatga aatcgaatca attactgata caaaattgca aaaatacttt gatatgtaca
    55561 atcttaatat cgataatctt attggtaatt atgttgaaga gatttatcat ctagaaaagt
    55621 aaagagaggt agttttactt atctctccat ctccttaccc atatatttct cataattttt
    55681 tctgatttga taaagttctt tcatatcgga ttttgtagaa gaatattctt gcataagggt
    55741 attctttttt tcgtgtagtg aatccaacgc tgctaaaata tccttagaat ttggaagttt
    55801 agaataagat tttttgaggt ctgaaagggc gttctggtac aaggtaatct cagctttatg
    55861 ctcgtcaaaa aatcccttat cagatggctc tttcttatat ccctgataga tttggcgata
    55921 aattttgaca gtatgaacct gctccatagt tgaagataga gcagaaatct tgctatctaa
    55981 gatcttgatt tcatcttgca gattttgcct tttatcagca ctttccttaa taaaatcatc
    56041 aagctgagaa atggacttaa agcctttttc acgcattaaa accaccatat tggtagctac
    56101 ttgaaggttg tgtttagtag cccaatattc atatcccttg cttgatttga ccttttcatt
    56161 attagcaata tcaatgatat ttcctacacg ctttttgaca gtataggttt tttgattagc
    56221 attctttgta atacgctctt ttaatttatc ttcagtataa tcatctccaa tagtctttgc
    56281 tcttgtaaat ctttctttgt ccttatgctt aaaggcaata tgttttccgt acttgatttc
    56341 atagtcaatg gcagccattt tctttagaaa ttcatcccaa tctttagact gtttaatagt
    56401 tctatcaata tcgaattgaa gcctactttt ccaagaagta cctttcttaa attgttcatt
    56461 ttcataccaa gacttcccat tagttttata ttttttctta taagtttcgt agaattcgtc
    56521 aataacagag agcttatttt ctttgcagag cttatcgctt tgatacctaa ttttatgata
    56581 gcttcttttg ttggattgat agcacttgcc agtaatcata ttcacattat tgaagatgat
    56641 atggttatga atatgacctt tatcgatgtg agtagtaagc acaaattcat actgatcctt
    56701 aagtattttc ttacataatt ccataccaac tttatgtgcc atttctggtg ttgcttcgcc
    56761 tggtaaaaaa gattgaatga ggtgtcttgc aagtacagtt cctttcacat tattatcttc
    56821 tctagtcttt aaaaactgag tatgagcagt agaagtaaag caattatttg tgcttattaa
    56881 aatcttctca tcagtttttt cttcgttagt aatgtaagca atagcaaggt taagtgttga
    56941 ctttattgga tgtatctttg taattgccat ttatacttca tctcctttat ctgtagttct
    57001 attaagcagt agtgaatgaa tttgccatat ctcttttgat aaaccttcaa tctgagattt
    57061 catatccttg atgtcatcgc tataaataac gccagttgaa ttgacacgct tagcgatttg
    57121 attaacacta cttgcatatc tgaaaagtag tccttgtatt tctctgaatg gttgtaaatc
    57181 tacaacataa atatctgact ctgatacaag ctttcttaaa aaaaggctca tggttttgca
    57241 cttagccatc ttcattttct tttcaaaaaa tgctttttct tcttctgtta agttgatttt
    57301 gagttgaaca tttctaactc tatttgccat attgattact tcctttcata aaatttctgg
    57361 ggttttaggg tatgccctaa caagttaaaa ttgataaaaa aagaagcagt tccacgaggg
    57421 gctgcttcat caatttttcg taagtgggta cacacttact gtgcttgctc atatactaat
    57481 cgatcatata ctaatcgtgt aagaacaact ttaagcataa tatttatatt attataccat
    57541 agtttggaaa aataaaaaat tatatttcat caacgtttca taaaaggtgt gtagaatatt
    57601 attgaaagta gttataaact gctattgtgt aaaaataaag gaggaataaa ggaggaaaaa
    57661 tttatgaaaa aaatagtatc aagaggagca tgcctattac ttacgttatg tttgagctta
    57721 agtacagttg ggtgtaaaaa aagtaatgaa agcaataaaa ttaaagaagg acaatctata
    57781 agttctgaag aggcaggtat gtcaactaat gagaaggata aaaatgaaac atttaagcca
    57841 tcagattata ctttaaaaac aaaaaaagaa tatgtttatg aatatttagg tcttaaattt
    57901 aaactttcag acaaatttaa aaagtatatg gatgataaaa agatagcgat gttagatgat
    57961 caaagtccta tagataagga actaaagtat gcttttttaa cttttaataa aatgaccgaa
    58021 gagcaaaaaa atgcagttat taataaaaag ggagatggtt atgaaaaatg gaagaatggg
    58081 cttaaaagaa ttggaactat tggtatattc gaaaaaaata catcagaaga aaaaatatct
    58141 aaaattacaa aatgtgatac ccatactaaa ataggagttt caagtgatgg aaaatacgat
    58201 tgctatttaa gcacaaatag cggatctgaa agtaatcttc tggatgaatt taaaaaaact
    58261 gagattcaaa ttatagataa aaaagaacgt cctaaaaatg gttttgtgct atcagaaaaa
    58321 actgatttag aaaatacaga agcatttaac aaagaatccg ttaaagattt acgtaaacta
    58381 tcaacaaagg acataaatgg caaggatttt acaagtaaag attttgataa gtatgatctt
    58441 actatggtaa acgtatttgc aacttggtgt acagcttgtg taaaagagat tcctgattta
    58501 gttgaggttc agaatgaaat gaaaagtaaa ggtgttaata tggttggtgt tgttacagat
    58561 actgttgatg ataacggtga aaacaaggaa gcaattgaaa agtcaaaatt aatacagaaa
    58621 aaaacaaagg cttcatatcc tttcttaatg ccagacaaga caaactttaa tggtagattg
    58681 aatggtatac aggctatgcc agagactttc tttgttgata ggaatggaaa cattgtaggt
    58741 gatacttatt ctggggcaaa gagtgcaaag gaatggaagc aggtaattga aaaagaatta
    58801 gcaaaaataa aaaataagta aatgtaaagc ggtgaatggt atatggttaa taagttttta
    58861 aaaagccgta ccttatcttt agtaattgtc tttattagta tggctatgac ttactatgga
    58921 catagtcatg gagaggctag agttgtattg gagaaggcga taagaatttg catggagtgt
    58981 gttggaattg gatagaatta aaaaaattat aaacggtagt acaaaaaaag ataaatataa
    59041 aataagagat cgttttagac atctatttca atccgtttgg tttttagtta ctaattctta
    59101 ttttgaaggg tttaagacag gtaaaatcta tggtggggac ctgaaggaag tttgtgttcc
    59161 gggtatgaat tgttattcgt gcccgggggc aaaaggttct tgtcctatag gatcgctaca
    59221 ggcagtgatt ggaaattcga actataagtt tagctattat atagttggct ttatgttctt
    59281 gataggtgca cttataggaa gatttgtctg cgggtggcta tgtccatttg gattaattca
    59341 agatttatta cacaaaattc cattttttaa aaaaattgag acatttaagc ttgataagca
    59401 tttgagaaaa ttgaaatata taatattgat tgtatttgta ataatacttc ctctattttt
    59461 agttgatatt ttagggcaag ggtctccata tttttgtaag cttatttgtc cagttggtat
    59521 gcttgaggga ggaataccac ttgtattatt gaataaaagt atgagaggag ctataggttt
    59581 tttgtactat tggaagggag taattttaat acttacttta ttactttcaa tagtaatata
    59641 tagacctttc tgtaagtatg tctgtcctct gggggctatt tattcagttt ttaacccgat
    59701 ttcagtattc aggtatagac tagacgaaga aaagtgcatt agttgcggta gatgtaaaaa
    59761 agtttgccaa atgaatatag atccagttga aaattgtaat catctagaat gtatcagatg
    59821 tggacgatgt aaaaatgctt gtcctgtgga tgcaattagt tgtggaataa aaaaatagag
    59881 aggagcttat tagaaaagtg ataaaaaaat agagaggagc ttattagaaa agtgataaaa
    59941 aacgcaatag catatattac aagaaaaaaa aatagaacat ttattatttt tgttatttta
    60001 acaatagttc tttcttgttt gtattcttgt ttaacaataa tgaaatcaag caatgaaata
    60061 gaaaaggctt tatatgaaag ttctaattct tcaatatcaa taacaaaaaa agatggtaaa
    60121 tattttaatg ttaatcaatt taaggatatt gaaaaattaa aagaaattga agaaaaaata
    60181 attcaatatg atggattagc aaaactaaaa gatgctaaag tagttagcgg agaacaaaga
    60241 ataaatagag aagatttatc tgacaaattt aagaatgttg tttcactcga agctacaaat
    60301 aatactaaaa gaaacatttt atttagtagt ggagtattta caattaaaga aggtaaaaat
    60361 atagaagaaa atgataagaa ttcaattatt gttcatgaag aatttgctaa acaaaacaat
    60421 ctaaaattag gtgatgaagt tgatcttgaa ttactagata ttgaaaaaag tggaaaaata
    60481 aaaagtcata aatttaaaat tataggaatt ttttctggta aaaaacagga aacatataca
    60541 ggactatctt ctgattttag tgaaaatatg gtttttgtag attattcaac aagccaagag
    60601 atattaaata aatcagaaaa taataaaatt gcaaataaaa ttttaatgta ttctggtagt
    60661 ttagaatcca cagatttagc cttaaacaaa ttgaaagagc ttaaaattga tgagtcaaag
    60721 tattccattg aaaaagattc taatgtgttt gaagagtctt tagagtcagt gagtggaata
    60781 aaacatataa taaaaataat gacttattct attatgttag gggggatggt tgttctttta
    60841 ttaatcttga ttctatggtt aagagaaaga atttatgaaa taggtatatt tttatctatt
    60901 ggaacatcta agatacaaat tataatgcaa tttatattcg agttaatatt catatcgata
    60961 ccaagtataa tatcttcctt atttttagga aatgtattac taaaagtaat tgtagatgga
    61021 ttcattaact cagaggactc aatgatttcc ggtggaagtt taataaataa tagtagtttt
    61081 atgttaaata taacaacact tggagaaagt tatttaatat taataagtat tattgtttta
    61141 tcagttgtat ttgcttcttc attaatatta atcaagaagc ctaaagaaat attatcaaaa
    61201 ataagttagg agaaaataat ggatatatta gaaataaaga atgtagcata tagttatgca
    61261 aattctaaag aaaaagtttt atcaggagta aatcaaaaat ttgaacttgg gaagttttat
    61321 gcgatagtag gaaagtcagg aacaggaaaa tctacacttc tttccttatt tgctggactt
    61381 gataaacctc aaacaggaaa aatattgttt aagaatgaag atatagaaaa gaaaggatat
    61441 agtaatcata gaaaaaataa tatatcttta gtatttcaaa actataattt aatagattat
    61501 ttatcaccaa ttgaaaatat tagattagta aataaatcag cagatgaaag tatcttgttt
    61561 gaactaggtt tagataaaaa acaaataaaa agaaatgtta tgaaattatc tggtggacag
    61621 caacaaagag tagctattgc tagagcattg gtatcagatg ctccaataat actagctgat
    61681 gagcctactg gtaatctaga cagtgttact gctggagaaa taattaatat attaaagaca
    61741 ttagctaaag atagaaataa atgtgtaata gttgtaacac atagtaagga agtagcagat
    61801 gcggcagaca ttattttaga actaagtggt aaaaagttga aaaaagtaaa taaaatgaat
    61861 ttggaggttg aataatgata aaaaatgcat ttgcttatgt aactagaaaa agcttaaaat
    61921 cattaattat tatattagtt attttatcta tgtcaacttt aagtctcatt agtttatcta
    61981 ttaaagatgc tacggacaga gcttcaaaag aaacatttgc taatataaca aatagctttt
    62041 ttatggagat aaatagacaa gtaaatccag gaacacctag aggtggggga aatgtaaaag
    62101 gtgaagatat taaaaagata tctcaaacag atagtgtaga ctcctatgta aaaagaataa
    62161 acagtgttgc agatttagtt gattatgata ttattgaaac tcaagagact cttgcgaatc
    62221 aatcacctga aagagcgaag aattttaaaa gaacagttat gttaactggg gttaacgact
    62281 catcaaaaga aacaaaattt gtatcagaag catataaatt agtagaagga aagcatttag
    62341 aaaatgaaga taaaaataaa atcttaatgc ataaagattt agctgaaaaa aataatctta
    62401 aagttggaga taagataaaa ataaaatcta atttatttga cgctgataat gagaaaggtg
    62461 cagatgaaac agtagaagta gaaattaaag gtctattcga tgggcataat agcggtggag
    62521 taagtgcagt acaagaacta tacgaaaata cattaatcac tgatgttcat acagctgcta
    62581 aagtttatgg taatacagaa gatacagctg tataccaaga tgcaacattc tttgtaaaag
    62641 gtgataagaa tcttgatagt gtaataaaag atcttgggaa attagatata aattggagag
    62701 aatataattt gattaaaagt tcatcaaatt accctgcatt acaacaatct atatcaggta
    62761 tctactcaat ttcaaataaa ttatttgttg gctcattaat atttgcagga gttgtagttt
    62821 cattattact attcttatgg atgaatgcta gaaagaaaga aatagcagta ttactatcat
    62881 taggtatatc aaaattagaa atttttggtc aattcctaat tgagatggta tttatatcaa
    62941 tccccgcatt cgttggttct tattttttag ctcaatatac agctggcaag cttgggaata
    63001 atatattgaa taaggttact ggtgatatag ctaaacaaat agctagacaa tctgcatcta
    63061 gccaattagg tggtggggca gaagctgaag gctttaataa gacattatca agtttagata
    63121 taaatgtatt acctaaattc ataatttatg tagttatatt tatgagttta gtacttcttg
    63181 tatcattgat tatttcttca ttcaatatat taagaaggaa cccaaaagaa ttattaattg
    63241 acaataatta aaagttttgg tgctttctag caccgaaagt tttttgactt ttaaatatca
    63301 aataatattc tgtataatat aagtgtatag gcttaagtgg aggtatatat gaaaatatta
    63361 attgttgaag atgataatat gataagagag ggaataagtg aatatctttc agaatttgga
    63421 tatactgtta ttcaagctaa agatggaaga gaagctttgt caaaatttaa tagcgctata
    63481 aatttggtta tcttagacat tcagatacct tttataaatg gtttagaagt gttgaaagaa
    63541 attagaaaga aaagcaattt accaattcta atcttgactg catttagtga tgaagaatat
    63601 aaaattgatg catttactaa tttagtagat ggatatgtag aaaagccatt ttcattgccg
    63661 gtcttaaagg ttagaataga ttctttaatt aagaagaatt atggacattt agagaagttt
    63721 gaatataagg atctatcggt taactttaat agctatacag ctaaaataaa tggtgaagaa
    63781 atagatgtaa atgcaaagga actagatgta ttaaaatgtt tattggataa tgatggacaa
    63841 gtgttaacaa gaatgcaaat tattgattat gtatggaaag atagcgaaga aattccttac
    63901 gatcgagtaa tagatgtata tataaaagaa cttagaaaaa aattacaatt agactgtata
    63961 actactataa gaaatgtagg gtataaattg gagataaaat gagaaaatga aaaaattaaa
    64021 gatatttccc aaaatgttca tacaaatatt ttctgttctt ggaataataa ttatattagt
    64081 tcattcatta gtttttttta tttttcctaa aacatatttg gagaccagaa aagaagagat
    64141 tcataataag gcaaatgaaa tttccagtaa tatgaatgga aaagaaataa aatatataga
    64201 acaaactttg gatctttatt ctaagagtag tgaaataaag gcatttataa aagaaaaaaa
    64261 aaataataat aatgaaatac aaatcaaaga taatatagat gctaatttag aaagcaatag
    64321 taattctttg ataattgaag aaagagaaat aaagcttaat gatggtaaaa aaacatatct
    64381 acaatttgtt tctacagctg atatgcaaaa agatgcaaaa gatttaagtc ttaaattttt
    64441 accatattct ttattaatat caattttatt ttctgctatt atttctttaa tttatgcaaa
    64501 attaataaaa aataatatac aagaaataaa aattgttact gataaaatga tgaaacttga
    64561 taaaaaaatg cgtttaaaag ttagctctaa tgatgaagtt ggagaattaa aacaacaaat
    64621 taatgatttg tattctactt tattaagaac aattgacgat ttggaattta aaaataaaga
    64681 aattttaaaa ttagaaaagt taaaatatga cttttttaaa ggtgcatccc atgaacttaa
    64741 aactcctctt gctagtctta aaataatact ggaaaacatg aaatacaata ttggaaaata
    64801 taaagaaaga gatatttata ttaatgaatg cattgaaatc gttgatagtt taacaaaaaa
    64861 tatttctcaa atattatcag ttcattctat agaaaatttg aataatgatg aagaatattt
    64921 gaaaataaat gatacaatag aagacatatt aaaaaagtat gaaatattag caaatcaaaa
    64981 gaaaataact gtcaataatt atatattaga tgagaatgtt tatataggaa aaacagcttt
    65041 aaagattatt ctatctaatt tgattagtaa tgcggtaaaa tatactgatg taaatggggt
    65101 aattaatatt gggatagtta atgattggtt atatatagag aattcatacg gtaacaataa
    65161 aatttcgaat atggataaaa tatttgatgt taaatttgat ttaaataagg aaaatagtaa
    65221 tggattaggt ttatatattg taagtaatat tctgaataat tacaatatag aatataaagc
    65281 attgcaggat gaagaatttt ttatctttaa aattaaaata ttttcttaaa taagatataa
    65341 ttttgcaata gttattgaaa aatagagact tattattagc catggaagta aagacttttt
    65401 tcttattgaa agtgaacaga gaataattga tacaagaaat cgggatttga acacgctaat
    65461 aaaaatattg ttagtaaaac tatatgagtt agtcttttcg gatgcagaga ttgtttaaat
    65521 atttgataga atagaaactt aaaaagttta ataaaactca attatataag tagtagatga
    65581 atatgatggt tatttagatt attgataaaa tggaggaaat aaatatggaa gcatctaaac
    65641 gtttaatgtt agaaatattt agaattcaat atattcctct tttttataat atgtatagta
    65701 gatgattgtt tcaggtgcga attgaaacaa tcaagttcat ataaagaaat atttttattc
    65761 tttcatttca gaggacttct tatgccaaga tgcagaagtc ctcctttttt atctgaaaaa
    65821 caagcagata aaaaagagat ggaggaaact ttatggcaaa agagtattat ctttatatca
    65881 gaggacaaaa ggtaaaagtc agtgaagata tatatatagt ctactggcga gaaaaagaac
    65941 acgagaagta tttagagcag gtggacagga aaaaccactt gctctttttt tcagcattgg
    66001 atcatgacgg acactttaca gataatattg ttgatgaaag tgttgatgta gaaaagattg
    66061 ttgaaacaca gatgatgatt gaagcagtaa gaagtgctat aacaaggctc aatgcagaag
    66121 aaagagatat tattgaacgc ttgtatttca atgatgaaac tgttcgttca gtagcaaagc
    66181 tcaaaagtat tacacatccg gctttaatca aaagaagaaa caaaattctt gaaaagctga
    66241 aaaaatttat cgaagaactt taaaacttcg gtaaccaaag ggggcaaatt ttccttatgt
    66301 aaagtgaagg ggagtttgac ctcctttact ttcttgagta ggagatacgc ctgcttatgg
    66361 caaataggaa aatgtaaaga aaacagtccc tttcaaatat tgctctttga caactgaata
    66421 gaccaaggta ggactttatc tacttactga gagttatgac ctacgccaag acttttctgc
    66481 tgatgaaaat cggttcaaat gaataccgtc ataatgccga ggttagaaga aaatgagcga
    66541 tagataggaa tacataaaag ataagcgtgg cagcttattt cgatgatgta agtggtgata
    66601 atgatacttc aatagtttaa gctgcctcgt ctgaaacaag gggcggaggt gagattccta
    66661 tgtagcagcc aatgcaccta ccaatgtcat aaaacttagt aagaaaaata atatttggtt
    66721 ataaagaatt taaagtggag gaggtgtatt agtggataat gactggaatg gattggctga
    66781 tttgatagca aatctgatta caaaatatgc tggagtttta gatttagaga atcttccaaa
    66841 tcctactcca gtaaaaaata cagaggataa gaataaattt gatatagcta aaagcacgga
    66901 ttgagaaaga gaaataaaag tgctataata tacttgagat taaagtccaa acctttattg
    66961 gtaaaaatat ataaatatat aataaggata ttgaggttaa tgctatgtca aaagaaaaaa
    67021 taaaagtata tctctataca agagtatcta catccataca gatagatggt tattctttag
    67081 aggcacaaaa atcaagaatg aaggcttttg ctctctataa tgattatgag attgttggtg
    67141 aatacgaaga tgcaggtaag tctggaaaat ctatagaagg tagagttcag tttactcgta
    67201 tgatggaaga tataaaatcc ggaaaggatg gagtgtcttt cgttcttgta tttaaactat
    67261 cgagatttgc aagaaatgct gctgatgtac tttcgacttt acaaataatg caagattttg
    67321 gagtaaatct tatttgcgtt gaagatggaa ttgattcatc taaagatgcg ggtaaattga
    67381 tgatttctgt tttatcggca gtggctgaaa tagaaagaga aaacattcgt gtccaaacaa
    67441 tggaaggtcg cattcaaaag gcaaaagagg gtaaatggaa tggtggattt gctccgtatg
    67501 gttatcaact tattgatggg aaattgataa taaatgagga agaagcaatt gcaataagaa
    67561 ctatttttga tcaatatgta aatacaagta ttggagctaa tggtctttct aaatatttag
    67621 aaaatcatgg tataaggaaa ataccaagac aaaatgggaa aaatccattg tttgacgcag
    67681 gtcttataag aaaaatatta aagaatcctg tgtataacgg gaaaatagca tttggaagaa
    67741 gaactttaga aaaagttcat ggtacaagga atgaatacag acaagtagag caggacgatt
    67801 atttagtagc agaaggcatt catgaagcaa taatcccaga tgaattgtgg caggctgcac
    67861 aagttaaact gaaagcacaa gctaaaaagt atgaacatgt aaataagggc aagaacatga
    67921 ggacacattt attatcagga atagtaaagt gtccaatatg tggagctgga atgtttggga
    67981 acaaatctat aaaatataaa aaagatggga cgaagtataa agacttctat tactatggtt
    68041 gtaagcatag acttatgaat agaggacata aatgcaccta taacaaacaa attagagaag
    68101 aattgttaga cgatgctgtt gctgaggtaa taatcaagtt agtaagcaac cctaaatttg
    68161 cgtctatgat gcaagaaaaa attaacatga aggtcgatac atctgctatt gaaaatgaga
    68221 tagataatta ccaaaaagag ctgagaaaaa gtcattctac aaagtttaag ctaattgaag
    68281 aaatagataa tttagatgtt gaggataaac actataagag aaggaagaat gatttagatg
    68341 atagacttta tcgtatgtat gataaaattg aggaattaga aagtcagtta atagaagcta
    68401 aagcaaaaaa agaaacgata gaggttgaga aacttactgg tgataacata tataaagtat
    68461 tgatttattt tgacaagctt tataaagtca tgaacgatgt tgaacgcagg cagttaatag
    68521 aagcactcat ttcagaaatt caaatttatg aagaaaagca gcctaatgga caatggctaa
    68581 aatccattac ttttaagcta ccgatcattg ataaggatct aaatataagt ttggacaatg
    68641 ataagcaagt tgaaactgta gctaagataa tcaaacaata gtaatgttta tatagattat
    68701 atactaataa tatattgtat ttgccaccga tttgccactg taaagcgatt ttggtggcaa
    68761 atttagtcta caatgttatc aaaaatctct aaagttttat ttttaattct ataaaactta
    68821 ttataattgt aattttaaaa gaaatcgtca atctacagta gccagatttt atacaactca
    68881 tttttttcat agaataattt acataatcta tagttgaata ttatttaata tttttatatt
    68941 ataattcatt agcaaatata ggcattacaa atgttgataa acatgtgaaa gcacatatcc
    69001 acttataatt attttttttt aaaccataaa atcacctctt catttgttgt atgtttttat
    69061 aacaaatgag gaggtgattt ccaaacaatt taaaaggttt ttgtatattg actaaaattt
    69121 atttttatta tttataattc ttaataatac atatgtacct actgattcca tattaaactg
    69181 tataattttt gttcatcttt ttttataatt aaaactacat agttttcata atttctctta
    69241 tatatatact tatcatcttt tttaacttct aacttatatt ttttaaaatc ttcttcaatt
    69301 ttatttttat tacttttatt aatgttaaca gaatctcttt taaatttatc aatatatttt
    69361 tctatttcat taatattatc tttgcttaca actataccac cttttaaatt aaaaactttt
    69421 ttgaaatttt tttcagaaaa tccttgaata aaataacttt gtccatctcc attaatacta
    69481 tcttgagtat caaatacttc aatttctttg ttaggtattg gtatatcaaa attccaagat
    69541 tcctttagca ttgaaatatt agctgttttt cctaaaaaaa gattatatag gatacttcct
    69601 aataacaaaa catctattaa tagtagtgtg attaatacaa tttttctctt tttcattttt
    69661 cgttcacaac cttttgaaaa aacatgattt aattcatcat ttgaaggcat gtcttcaaga
    69721 ataatttttg ttgtgatagg aatgctttct tgaaacatat catttgtaat atcaaaatct
    69781 tttctttgat tactcaatat ccatttcttc taatatttct tttgattttt tctagtacat
    69841 tgaatactct tatatacatt ctcctctttt aaaattaaaa gttataaaag aataagttat
    69901 ataaaaaatt attatatttt ttaatatagc ttatttgcaa atttataatt ttgttaatct
    69961 aatccttcaa actaaaaaat catttatgtt tgcagaattt cattttaaga gatgtttatt
    70021 ttcacataga taagagaatt taagttctca tatttattat ttgatacaaa tttacatctt
    70081 tattatatgt attttaaata aaaaataaaa ttatgaatac tagaaatcta tcttaattag
    70141 ctttctaaca taaggctatt taaagtagat aaaactaaaa agggttctct agaaaaccaa
    70201 atctatttaa ttatacttac ttactaatac catcacttga tgcaaacaag attctaccac
    70261 attttctccg tactctagta taaaatcatc tagttgtgta tctataaaat cacaataatc
    70321 atatgaacta ccaatataag cagtcaacat atgtgtacat ctatccattt tatctctaaa
    70381 catatatatt attatccccc taaaaaactt tcataaaaac aaaaagaata tctctttttg
    70441 gcaactggct gacataactc atagtttatt ttataagcgt tagtccctat agctttgcgt
    70501 cactaaattt ctctagtttt gccgatttag ttttattcta caattacaat aatacaatag
    70561 aattgcttat tattcaatat acttatttga aaattaaata aatttacaaa tatgaacgtt
    70621 attttatatc aaaaaaatag actatgcatg tagaatatat ggaaaaactt gattgtaggt
    70681 tttgtatgaa aagacagttg ttattaattt aagtgagata aattgagcaa caggcataaa
    70741 atgagaaaac aaataatagc agttaatttt tattattaat actaggtgaa cattaaattt
    70801 taaaatacca ctagatttta tagaataaga aaatgagaca aacataaata tatgaatata
    70861 ttaaattata cttgaacata cttatatttt atgataaaat ttcaataata attattagtg
    70921 aaggagtgtc ttgcctgatg tcagagttat atataatggt aaccaacaaa taaatagttg
    70981 gagacgcata tgggtcctgt ttaatcagaa tttttaagtg tatttttgat acatttgatt
    71041 gttgtgtctt actctgcctt tatagataac taacattaga caacaaataa taatattaca
    71101 tattactttg ttaaattgtg gtgtagtggg ctttaatctg ctacactttt attaatttta
    71161 cacagtatta ttttgaatat aattatgttg aaatagaaga tactaaattt tctagtccac
    71221 aggggttttc tgtttttgtg taggtaaata tgtataccac ataaaaaggc agatataaat
    71281 acctgtggac tttttttgta gaaaatacaa gatacggagg aaataaaaat gaattataaa
    71341 aatagaaaac gagcttatta tcaggaaaat tcctgtatgg ataactttat ttgcaaaaat
    71401 tgtggttgtc ttgtagttcc tgaaggagct ggtacacaac atagaaatca ttgtccacat
    71461 tgtttacata gtcttcatgt agatatcatt cctggtgacc gtgctgcaga ttgtgatgct
    71521 aatatggaac ctattggagt gtgggtgaga aaaaatggtg agtgggcaat tattcatcgt
    71581 tgtacacgct gtggacatct tagttctaat cgtattgcag ctgatgataa ttcagtgaaa
    71641 ttaatgtcaa ttgcattaaa accactggca cagccccctt tcccactaga aagaatcatt
    71701 gaaaagttgg aaaaggagga aacagaatga atggtatgaa acaaatcaat ttacaagact
    71761 atggtctaaa tagaaatttt attactcaaa gtatggaata tcatgattta taccttgctc
    71821 ggattatctc gcaggaaaag aacttttatc aagctgtatg tgtaaatggt gtactgtttg
    71881 cagaggtttc aggaaagctg cgttttgagg ctactataca atctgatttt cccacagttg
    71941 gtgatttcgt tatgttggat cgttgcaata ataaaaatgg taatgctatt attcatcatg
    72001 tgcttcatag aaaaagcttg tttgtgcgta aggctgctgg aaaggtaaat gaggagcagg
    72061 tggttgcagc taatattgac attgtttttt tgtgcatgtc actgaataag gattttaaca
    72121 ttcatagatt ggagaggtat ctgtctttaa catgggaaag tggagctatc ccagtagtag
    72181 tacttactaa atcagactta tgtgacaatg tgcatcgtaa attacaagta gttaattcta
    72241 tagccttggg tgtagatgta gttgttacct catctataga gccagatggt tataaacaga
    72301 tttctaagta tattaaacca ggctgtactg ttgccttact tggttcttca ggagttggaa
    72361 aatcttcatt aattaattgt ctgatgggtg gagaattttt aaatacaaag gaaattcgca
    72421 tagatgatga taaaggaaga catgccacga ctagacgaga gctattttta atttcaggtg
    72481 gtggtattgt tattgacaca ccaggtatga gagagttggg aatgtgggat gtttcagaag
    72541 gtttagataa aagttttgca gatatagaag cttatttcgg aaaatgtcat tttcgtaatt
    72601 gtactcacac ctcagaacca ggctgtgcta tctgggaagc tattgctcat caagaacttt
    72661 cgcctaaaag atgggaatcc tatcgtaggc ttaaaactga agcagtattt gcagacaata
    72721 aaagcgaata cttagcaaaa aaagaaaaga aatttaaaaa tatctcaaaa ataaataaga
    72781 agattagaag ataagtgtag tttttttgtt cattctatga gtctatatac tattaatata
    72841 ttaaatttgc catcaatttg ttactttaat gtgattttga tggcaaattt ggtttgtggt
    72901 attatttaaa gcaatttatt aattttttta ataaagtttg attttttata tgatgatata
    72961 tacatgtgat aatgtataca tatttgttac gataggcttc tttataaaga ggtcttatgt
    73021 aagataagaa aaggcatatt tatactaata cataatagag tatatgctta tgtatgatag
    73081 agatgtttct taagagcaaa actgcaatat tgctaattta taaagtaaaa atatatgaat
    73141 tataaaatac aaataatata tttataaaaa ttattgtttt aatttataat aaaaattttt
    73201 tgttgaaaat aatgctcgaa cctataaaac tattaactaa tatttgtaaa tgtatacttt
    73261 tgatgataaa atataattaa gttaagttgg tttctataaa cataaattta ttttagggag
    73321 gtgaaataaa tgaaaatatc tagtcaatat agaagtcaat attcatttag atatgaaagt
    73381 aatataaata atacaagaat aaatgaaaat atggttaaga aaaatgaaac tgtaggaaaa
    73441 gacacttatt tatctaatat tatgaaacaa aagcaagaac ttaatgatag aattagagat
    73501 ttaaaatata gacaagaggt ttatgctaaa aaaataaatg acgcaattaa gaacttatgt
    73561 aaatcagaaa taagagaaac aactaataac ttttctaata tagaaatagg tattaaaaat
    73621 agcattatag aagataaaaa taaaagtaca atgttagatg aaaattcaac ttatctaaat
    73681 acaaatgatg aaaaagaatc tttaatcact aaagagtcta atgaaaaaat tgaagaagaa
    73741 atattaaatg atgaaaaatt agaagagtta gaacaaaaaa aggattataa agaggattcc
    73801 aataaaaaag agaaagtatc tgaggactta tctttagtag gtaaaactcg tgaagagctt
    73861 gaaaatatgc ttaaaaattt tataaattta acacaagaag aaataatgaa acttgagtcg
    73921 agaatagaaa agttagataa agatgctgaa gaatacaaac aaaattcaaa gactaatata
    73981 tttgataaaa cagatgaaca aaaaaaacat ataaatgtac tgatttaaac aatatgtttt
    74041 aaaaaaataa gtttattata taatgaaaat ataaaggtac aatttcaata cacttctatt
    74101 aaaccaataa tttatgaatc agatttaatt tcaatttact aataaccata tatttatgag
    74161 ttaataattt tatgttttaa aaagaattaa ataaggggga gtagtatgaa gaagaatata
    74221 ttaactacta tgattaccat gattattata ttgatgatga gtatgacagt aatggcagag
    74281 ccatatcaag aagatgaaac atctagcttg aaaaaacaga gtgcaaatga acgtaatcag
    74341 actaatatag gcacaatgga tggcagagtg caaacaaatg caataagtaa aggtgctaat
    74401 tatgacccta aatatcctct taaaggaatg ttaacacaac ttggtcttaa tacaacaggt
    74461 aaagagggat gggatttact ctatggagga aatcccaatg gagttgagct tcgagcagat
    74521 ggtaaatatt attatataaa taaaggtatg gaagggctag gattttatgc ggcagcattg
    74581 tcaggtggct catatcagag aataggcttt ggaaaacttg accctataga agtaatagcc
    74641 gatggaaatt ggatttctta caaacaagct caagatacac ttacagtaat caggaatttt
    74701 ttaaatagtt ttgactggag aaatgcatct gagatggaaa gagctaatag agctgcaaaa
    74761 ttggtaaccg aagcaaaata tgcagactct aaatattgta atatagtcta tggtaatctg
    74821 gttgataaac gtggtgtatg tggaagtttt gcaagtagct ttcatttatt aacaaggtta
    74881 atgggaatga attcactatt tatattaaat ccgtcattaa atcatgcttg gaactatata
    74941 caaattgatg ggaaatggta taggtttgat gggtctgaaa tatcagcttt tggtggatca
    75001 ttagactttg attaccgtaa attaaaggat gcaacaagag agatgactac ttactatgat
    75061 gctaaggcat tgtctatatt aggatttaat caataaaaat aggggaggct tcttatagag
    75121 ccttttttta ttgatttgaa atttaataag gaattttata tgaaaattta atcaataaaa
    75181 gcaaaaaagg ctctttataa agcctttcta agtgtttttt taagtaaaat tttttatatc
    75241 aacatcagtt ttaatcaaaa catataacat tttggactta cttttaaaaa taaaattatt
    75301 aaaatataat attaatcatg ttaataatgt ttttagttta ttatattcta taatagtggt
    75361 catgttgact attgtagttt tattaagaat agttggttta tataaatata tgcaaagata
    75421 gcttgttgtt tactttactt attagtatat aggacaagat actctaataa atttgcctat
    75481 tttaatatct tttgtactaa aaccaactaa agtttccttt attatttcgt tttgaataat
    75541 acaaagcata atccgattgt ttgtataaag actggaaagt atcagagtta ttttctaatt
    75601 tagatatacc tatagaacaa gaattactct ctaggcataa ttctaaaacc ttctttgcct
    75661 tattttcaac attctctttt gattgattac tatattcaaa aacagcaaat tcatctccac
    75721 caagtcttcc aataatagca tcatttacga atactttagt caaaatattt gaaaaatgta
    75781 ttagtatttc atctcctcga acatgaccaa agatatcatt tacctgttta aaattatcta
    75841 aatcaaagat gtaaaagtat ccatgtgaaa cagttttaag catttctttt atgtgtactt
    75901 caaaaaaatg tctattgtat agtccagtca taaggtcttt ttctgatttt agtttaaatt
    75961 catttgccat tgctagtgct tcttgtgctt tttcagttat tgttttaggg taatactcat
    76021 ctttcatttg gtcaaagttt ggaatagaat ggtgaacatg gataagttta atcatatcat
    76081 ctgtaactct gtataccata gtaaatcgag tatccatttc tacatagata tctttttcta
    76141 ggtaatcttt ttctattacc caaagagtac catatactat aaaagcttcg tctgtaactt
    76201 tggtacatga ataccactca tctataatct caaagtctat ttgctctgat tctgtttggt
    76261 ctttttcaag acctataata aattcttcta atgtttcgta aaattcatgt tttcctgttc
    76321 caattaatgc aaggttgtca tctaataagg aaataataaa tttaaggttt tcttcttctg
    76381 gatttaaaat ataaatatgc caaatttttt ttgataaatc tcttaattgt ttttgtattg
    76441 tattattttc catagattac ccccttaaga tttacagttt atattttaat gtattataag
    76501 ttgaactctt attacaatat tattataata tagaactaaa gaaattacat cctgtatagg
    76561 taaaagtata tcttttacaa taaaaatatt acagtaaaat aaccagtttt aatatacgta
    76621 ttatattttt aatttataaa cgaatattat aaatgaaatt taaattcaac cctgaagaaa
    76681 taagctaaat gtattagtat ataaatccat acttgaacat aaataacctt tatgatatga
    76741 tatcaataat aatattatga gaggagtgcc ttgatgtcgg agttatataa tggtaaccaa
    76801 caattaaata gttggagaca catatattct gtataatcag aaattttaag tgtattttta
    76861 atacatttaa tttttgtgtc ttattctgcc tttatagata actgacatat gacaacaaat
    76921 agtatttaaa atatatatta ctttgttaaa ttatggtgta gtaggcttta atctgctaca
    76981 cttttattaa ttttgtatag tattattttg ataactattt tgaaatagag agtattaatt
    77041 tttctagtcc acaggagttt tctgtttttg tgctgttaaa tataagcaca gaaaaaggca
    77101 gatatatacc tgtggacttt ttttatataa attatgaaat atggaggtag ttaaaatgag
    77161 tataattgaa cttaatgaac tgactaaatc ttatagaaga tttgagaaaa aggcaggatt
    77221 tatggggagt gtaaagtctt tatttaatag gaaatataca gaaaaaacag ctatatcgtc
    77281 atttgattta aagatagaag aaggagaatt tgttggatta ataggtcaaa atggagctgg
    77341 caaaactact cttattaaga tgttaactgg tattattgta ccgtcttctg gagaaatatc
    77401 tgttatgggt tattacccta acaaattaga aaataatttt aaaaaacaat atgctgttgt
    77461 tatgggccaa aaaagtcaac tattctttga attgacacca gcagatacgt ttcttttatt
    77521 taaagaatta tatgatatat ctaatgaaga atataaaaaa aacttggatt actttatcga
    77581 attatttgag gtatctgact atttaaatgt tcaagttagg acgctttctt taggagaaag
    77641 aatgaaaatg gaactaatag tagcccttct acataatcca aaaatattat ttttggatga
    77701 accaactata ggcttagatg ctatagccca aaaacaaatt aggtatttcc taaaagaagt
    77761 aaatgaaaca aaaggaacta ctattatact tacttctcat tacatggaag atattaagag
    77821 tctctgtagt agaagtattg ttgtagaaaa tagccgtaaa atatatgatg gttctacaga
    77881 gaaactattt aatcattttc aaaaatataa aaaaataaca gttagttttt ccaatgaaac
    77941 taacattgta tttccaaaag attgtaaagt tgttgaacaa acaaatcata agatatcagt
    78001 aattgtgcca aaagaaagag gaaatgaaac gattaaatgg atttttgata aatatgatgt
    78061 taaagatgta atgattgaag aagaagatat aggtagtatt gtagagagaa tatataagaa
    78121 aggaagtgat gagtattatg agcaactata atgaagcaag ttcaaattat tcaatgtttt
    78181 ataaatttaa acagagtatt agaaggtatt atgaagtagc caaaattaat tttaaagtgc
    78241 aacttatctg gagatttgat gtggtggtta atatggtgtt tacgattgta aaaattttat
    78301 ttgcttatat tttatggaaa gcaatttttg gtgaaaataa aatagtctct ggttttacat
    78361 ttaactctat gttatcttac tatataataa gctcattttt agcaggtatt gatatgtcaa
    78421 agagtaccag tgaagagata tgtaatcgtg taaaattggg caccttttca aagtacatga
    78481 ttattccaat taatgttcaa aattatttta ttgctaaaaa ttttggaatg acatgttttt
    78541 attttgtatt taatatgatt tctgcatttg tatggatttt tatatttaaa atagattttg
    78601 cctttacatc aaatccagtt caaatattaa tttcaatttt gatgattttt ctagggttta
    78661 tttttatgat gaaactccac ttctttattg ggattttgtc atttaaattt cttgagatta
    78721 gtttttttag aatgataatt gaaaatattg ttgaatttat tacaggaaca atgataccac
    78781 ttgtactctt accagaaact atagtaacag ttatgaaggt atttccattt tattatacaa
    78841 catatttgcc atctatgtta ctaataggta gaaacagcaa tgaggcaata caaggattaa
    78901 ttattctagc attatgggtt ttattttttt ctgtagtaaa taaagttatg tataaaagaa
    78961 tgagaacatt atttgatggg gtgggtatat gatgaaaaaa aatttgaaaa taatatttat
    79021 gttattaaaa atgaaattat caaagatgat ggtatttaga tttgattttt ttggagcatt
    79081 ttttgtagat agttcattat ttatattaca acttctaatg tttaatagta tatattctca
    79141 tgtagactca atagggggat ggcaacaagg agagatgtta atatttatag gaactttctc
    79201 attaataaat gcgataaata tgacgatttt cttttttggt atttatgata ttccacgaaa
    79261 aatccaagaa ggagaattag actactatat tacaaaacca ttagatccac tatttaggtt
    79321 aacatttgaa aatattaata ttggttcatc accattaatt ctagcaagta tacttattgt
    79381 tttatatgga atatctgagt taaactcaga gataacttta gttatgataa taatatatat
    79441 tttcatggtg ttattgatga cattactttt ttatgatgta tgtatcatac ttagaacagt
    79501 ttcatttttt gttatatcat cttctgcgat aatgagatta gaagataatt tattgccaat
    79561 gaatatgaaa attcctggtg taatatatga aggtgttttt aaagtattat tctatttaat
    79621 cttaccatat ggaattatgt cgacaattcc gactcaaatt ttggctggga caataacaat
    79681 taatggatta atatactcaa ttttaattgt atttttgttt acattgttta tgtggagatt
    79741 ttggaagtta ggtatgagac attataaaag tgcaagtagt taataaatta gtaaaaataa
    79801 acaatgtata actatatata aatacgtttc atatgacact aaactatgtg aacaagtatt
    79861 tgcgctaaag gcactgaaag ctataaaatt attaaagtaa gaatttaaaa gtttctttag
    79921 tagaaatata attgtgtaaa aaagcaagat taattaaaac tatatccaaa taattagata
    79981 taattcttat gcagaaagga ggtctgtaaa tgtctaattg tttggaatat attttaaaaa
    80041 taattaatgt acagaaaaat aaacaaaatg agtgatgtat attattcaga aaatcatgaa
    80101 caagataatc tttatgagca agataattta ctggcacaaa gatttaattt atttactcta
    80161 ttgaagtttg catttcctac tatttttatg atgattttta tggggttgta tacaatcgta
    80221 gatactatat ttgtatcaag atttattaat acaaatgctc tatcagcaat taatattgta
    80281 tgtccaatta ttaatcttat agttggaatt ggaactatgc ttgccactgg aggaagtgct
    80341 attgtagcac gtaagatggg aaatggtgat attgagggag caaataaagc tttttcttta
    80401 atcgtattat caggagttgt aattggggta ataattactg gtataggtat tgtatttatg
    80461 gattatatca ttatatggtt aggagcaagt gaagttttaa ttaaatattg tcgttcatat
    80521 ctttttatta tcttggtttt tgcttctgca aatatactac aagtattatt tcaatgttta
    80581 tttgtaacag ctggaaagcc tcaatttgga ttatggctag tgttaggtgc tgggtgtgct
    80641 aatataattc ttgactatgt gttcattgtt ctgttacaaa tgggtattag tggagcagca
    80701 cttgcaactg gagtaggata cctaattcct accatttcag gtatggtttt cttttcaaaa
    80761 aataaagggt tacttaaatt ttgtatacct agactagata aaagaatatt atttgaagct
    80821 tgttttaatg gttcatctga aatggtgggt caactatcaa cagcagttac tactttttta
    80881 tttaatgcta tgatgatgaa attaattggt gaagatgggg ttgcagctat tacaataatt
    80941 atttattctc aatttctttt aacttcgctt tatataggtt tctcaatggg tgttgcacca
    81001 ataataagtt ataactatgg aagtgaaaat aatacgcagt taaatcatgt ttttaagatt
    81061 tgtatattat ttatttcagt agcatcttta ttggtattta tcttttctat atcatgttca
    81121 ccaatcattg tagagacttt ttctcaaaga ggaagccgag tttatgaaat tgcaaggtcc
    81181 ggattttata tattttcttt tagttttatt ttttgtggat ataatatttt tacctcatct
    81241 atgtttacag cattatcaaa tggaaaggtg tctgcaatat tatcttttct acgtacattt
    81301 ggatttataa ctataggttt attgatattg ccaaatatat taaatataaa tgggatatgg
    81361 ttagcagtac caagtgctga gattttaacc ttatttttaa ctgttttttg tatatttaag
    81421 tataagaata gatataaata tatgtagata ttaaataaat agcttagata gatattttat
    81481 gttttaataa gtaattcaat tagtggtaga tatatactat tgaaaattaa agttataatt
    81541 gatataaaga attaataaaa ataacatata aaagtttaaa agggagttga acttaaagtt
    81601 tgattagaaa aagtcaattt taagacaact ccttttattt tactattgta ttaatctgta
    81661 tctgtaagtg tattagtcta atattataaa ctttggatga aattaatttt ctataggttt
    81721 taatgtatca tacactttat tttaaagaaa cttatcttaa ttttcatagt gattgaattt
    81781 gtctattaga gatgttacta ttagtaatgt aaaagcaaga gtagtgaata taaaaaacaa
    81841 gatagtgata ctgcaagatt agaatataat aaatttttat ggagagattt caatatggat
    81901 acatgtttta ataaaaaaat attacttgtt gatgatgaaa aggatatagt agatttaatt
    81961 gaagaagtac tcataaatga tggttttaaa aacattatta aagcttataa tggtctagat
    82021 gctatttcgc tgtgtaagat agcatgtcca gatgttgtca ttcttgatat aatgttacca
    82081 gatatagatg gtatagaagt gtgtaaaaaa attcgagagt tttcatactg ttctattctt
    82141 tttttatcat caaaaaatga tgatattgac aaaatactag gtcttagtag tgggggagat
    82201 gactatataa caaagccatt cagtccaaga gaaattgctt ttcgagttaa agcgcaatta
    82261 cgtagacaac agtatcaaag cattgtacca tcagatagtg aagttattaa aataggagat
    82321 attactattg atatagaagg aaaccgtgta tataaagata gaaatgagat tgagttaact
    82381 ggaagggagt atcatctttt aagctacatg gctaaaaatg taaataaaat tataggaaaa
    82441 gaaagactct atgaacaagt atggggagta tatagtagta tttgtgacaa tacaattatg
    82501 gtgcatatac gacatataag agaaaaaatt gaagataacc cctcaaatcc taaaatactt
    82561 ataacagtta aaggactagg atataaactt gtgaatagaa tcgattagaa tagattttaa
    82621 tattaatgaa gatatctcaa gttgaatttt tagttaatga ggcattcttt tatgggtgaa
    82681 atcaaatgta ttttcgttat ctcaacaatg aagaagaggt ctatctctat tttgagatag
    82741 cctcattaag tttatatcct ggtaatgtac tttatgttct aataaaattt ttttagttta
    82801 tttgcagtga aacattaact agaacattaa aatttgcatt gaaataccaa ttaaataata
    82861 ttgtatattg tgtataaact tatactaatt gtttttctat attaaatact ttatcaatcc
    82921 aacctttata aaatttttct tcatgggaaa ctaggattat acttcctcta aactgtttca
    82981 aagcattttg taaagcatcc tttgtctctg catcaaagtg attggttggt tcatccagaa
    83041 taagaaaatt acaaggagat aacatcatac aacataattt aaccttagat tgttcaccac
    83101 cacttaaagt agatacactc cttgaaacat gctcttcctt cacaccacat ctggctagat
    83161 gacgtctaat ctcttttgta tttaattttg gatatttatc tgctactatt tgaagtgggg
    83221 ttttatcagg attttcccat tttaaatctt gctcataata accaatttta acttgttctg
    83281 aaaactggaa atctccagat atacgaggaa tatcttttac taatgtcttt aacaaggtag
    83341 atttaccgat tccattaaaa ccagttataa ctattttttg acctccatca acagaaaaat
    83401 ttaattttgg aagtaaagaa tagtagtatc caacttcaag atttgttata gtaagagcat
    83461 tttgagccga tatttcaatt tctgaaaatt gaatatttgg ttttcctgta aaactaggag
    83521 gagctattct ttctatttta tccaattgtt tttgtcttcc tcttgcaatt tttgaattta
    83581 ctccagcttt atttttacgt ataaatgttt cttctttttc tattttcttt tgttgtgctt
    83641 gataccttct aatataatct tctcttaaat gtgatttttg tttaaggaac tctgaatatt
    83701 ttccatgata tttcttaatc atgccaaatt ctatatcaag aatacctgta gaaatttttt
    83761 ctaaaaagtc aaaatcgtgg gaaactacaa taaatgcccc attaaatgta tttaaataat
    83821 ttgagagcca ttcaacatgt tctttatcta aaaagtttgt tggttcgtct aataatagaa
    83881 catcatggtt agaaagtagt aattttgcta aaattacctt tgccctttga ccaccactaa
    83941 gctctccaac aacacgattc attcctattg aatctaatcc aagaccattt gctattttat
    84001 ttatttcatt atctatagaa tagaaattat ttgctattag ttgttcctga taatctgatg
    84061 ctttgattag atattgccca ttttcagata tagcactttt ttgatagagt agattcattt
    84121 ccttttctat tttataaagt tcctcaaatg cagtgtgtaa atagagtgat attgttgtat
    84181 ctctattgat ttctgcatat tggtctaaat ggcctatatt gatattaggt tgccacttga
    84241 tttctcctga atctggaaca acttctccca ataaaatttt aattaatgta cttttacctg
    84301 taccattttg gccaactaca cctatatgtt cacctttgaa taaatcaaag ttagctttct
    84361 catacagtga tttatccata aaacattgtg ataaattagt tacttttaat aaactcataa
    84421 ttcaaactcc ttttctttta ttaaaaaatt tatggaaata aaaaaagcag aggaatggca
    84481 ttgtaaaatg ccgacctctg cttttggaaa aacaaaaggt catagacaag cattgttgtc
    84541 tatgaccaga aaatctatat tatctatcgg caaataggta attttaaata agcatagcca
    84601 aaaaactata ctaaacctat atttgccgat gaagatagaa agctttaagc tttcagatta
    84661 acctctacac aacgcttcat cgtatacatt tgtgtagagt taagttttct aacaagttta
    84721 actaattcta tataaatcat aattattcac atcctaatct tagtattaat tctagtttat
    84781 ctatatttaa attgtacttt tgtactttgt ggattatctt atttatttaa aatacgtttt
    84841 attaattata gcttaagtta tgttatcata atacttagtt atagtcaata agaaagttat
    84901 atttactatt attatattaa tttagtaaat ctatcattac aaagttattt gaagactcgc
    84961 tatcaataaa attttatagt ctataagaaa attaagatta tgagttttat aattttgata
    85021 tagggatact attttcataa atattacaac atgtagaagt atatgtctag tattgttgaa
    85081 ttttcaatga tatattaagg ttctaatata ttatacaaaa taaaaacatt aattcaactt
    85141 aaataatttt aagtattata tgtgttttga ttaaagaaaa ctaaaatttt aaggaaaaat
    85201 aacatatttg tattaaattt tattgaaatg attaaattta tttacttaat gtaaattatt
    85261 agctaaaatt gtattaaata attaaggagg tgagtagctc tggatgaaat agatttaaaa
    85321 ataattaatt ctctaaaaaa gaatagtagg gcttcaacct ctgaaataag cagacaaatt
    85381 aatttatcag taccagcagt ctcagagcgt ataaggaaaa ttgagcagtc aaatttaatt
    85441 caaaagtaca ctattcaaat taatcgggaa aaaacaaaat ataagctttt ggcttttata
    85501 tttatcaata ctgatttatc taaaagtatg aaagaattta agaaaactat attggaatat
    85561 gatactgtat tagaatgtca tcatatttca ggagagtatg attacttaat aaaagtatta
    85621 gcagaagata caagtaatct tgaagagttt atatcagtga ctttgaagga aattgggggg
    85681 attcaaaaag ctaatacaac cattgtttta tctacaatta aagaagaatt taatacaata
    85741 aaagatattt tttaaataat ttactagtaa agtgttaatt atattttagg aggaaaatag
    85801 aatatgaaag ttttagtttt tttagcaaaa ggttttgaaa ctatggaatt tagtgtattt
    85861 gtagatgtta tgggatgggc tcgtaacgat tatgggcatg atattgatgt agtgacttgt
    85921 ggatttaaaa aacaagttat gagcacattt aatatacaag tattagttga taagacgata
    85981 gaagaagtat gtgttgatga ttatgatgct ctagctattc ctggaggatt tgaagaattt
    86041 ggattttatg atgaagcata tgattcatct tttttaaatc taataaggga gtttaattca
    86101 aaagaaaaaa taatcgcttc tatttgtgtg gcagcattgc cagttggaaa aagtggtgtt
    86161 ttaaaaaatc gtaaagctac tacatatcat ttgaaaaatg gtaaaagaca aagacagtta
    86221 agtgagtttg atgtaaatgt agttaatgaa ccaattgttg tagataaaaa tattataacc
    86281 tcatattgtc cagaaacagc tccacatgta gcttttaagc ttttagaaat gttgacatct
    86341 aaagaacaaa tggatgaagt taaattagca atgggattta aactgtaatg gtttatagat
    86401 tttctaagta atcagaaccc cagtcacaca tggaatctaa aattggaatg atactctttc
    86461 caaaatcaga tagcgagtat tctacttttg gaggaacaac aggataaacc actcttataa
    86521 ttaaaccatc tgattctaat tcacgtaatt gttgagttaa catcttaggc gttgctttag
    86581 gaattaattt ttttaattca ttgaacctca atatagtgtc tttaagatgc caaagtataa
    86641 gtgtcttata tttaccacca atcaatgcaa gtgttgcttc tattgggcaa ctgtaattat
    86701 ctaaacattt tttcattttt gggctccttt atttatttta aagtatcttt ttaggtacta
    86761 tattacaaaa aagtgcatta ttgtaatata gtaccatagt gataaaatta tagcataggt
    86821 taaataaatc atcaacttag cctaataaaa caataggggg taaataaatg aatttcgttg
    86881 aacttgcaaa aaaaagatat tcttgccgta attatcaaga tagaaaggtt gaaaaagaaa
    86941 aacttgagaa ggttttagat gttgcaagaa tagctccaac tggtggtaat cgtcaacctc
    87001 aaagattgat tgttattcag gaaaaagaag gtataaataa actttctaag gctgccaata
    87061 tatatgatgc gccattagca attcttgtat gtggagataa agacaaagtt tggacaagac
    87121 cttttgatgg gaaacaactt acagatattg acacaagtat agttacagac catatgatgt
    87181 tacaggcaac tgaacttgga ttggcaagtg tttgggtgtg ctattttaat ccagatataa
    87241 ttagagaaga gtttagtttg ccagataatc tagaaccaat aaatatatta ttgatgggat
    87301 atgaatctaa gataccagag agcccagaga gacatgaaaa aactcgtgtt cctttaagtg
    87361 aaattgtttc ttatgaaact ctttaattat aaaattaagt tattcatagg ataaatgtaa
    87421 taaagtgttt attataaaca aaattcaaaa taaataatat ctacatataa ttaattttag
    87481 tgaagtatat ctagtttaac tagaatgtat acttcactaa tttatttatt caaaatattt
    87541 atgaggattt taatatatta actaaaatat atcaattgaa ttaactttca aatctggaaa
    87601 agcacttgaa atatagtgtt ttatatcatt taaatggtct tgaatttgct tttctgatat
    87661 tttatcaggt ccatatacaa aatacataat atttttagta tcttttgtta tagctgttcg
    87721 attatcaggg ccattaagaa tactagataa tataccaata ttatctgata aaaataaatc
    87781 atcttttgtt aaaatatgtt ctttaccacc tataccataa aaatgttcac ttccatttgc
    87841 taattctatt ttcaaaggta attccatttt atcaaggtca tgacctgctg ttagaagaag
    87901 atttttcaat tctgctaaaa acattgactc aattgttaca cctacatctg ggataccttt
    87961 tgattttaat agaatagatt ctaattgaag caatacaggg taagttttct tgaatttttt
    88021 ataatacttt atataacttg aaacaggctc tgttttaatt ttttctttac gattgtattc
    88081 tgggtgttgt tctataatat ttttaattgt agagttttta agaactaaaa aattttcttt
    88141 attaggtttt gaatgtgtaa tatttataac cataactcca aatttaatat tgggataaat
    88201 ttctttaact ttatgtgata tttctaacat aatatagact cctttttatt ttatatttta
    88261 tgatataatc ttagcaaatt aaaagtggat tttgtagttc catttttata gtaattttat
    88321 agaaccactt ttggaggtat tagaatgtgg attacgatta atagaaatag taatatatca
    88381 ttatcaagac aaatttattg tgagataaaa gatatgattc tggatggaag cttaaagttt
    88441 gagcaaaaac tgccatcatc taggacttta tcaaaagaac tatctgtatc tcgtaataca
    88501 gttttagatg catataatca attaattgca gaaggatatt tggaaacaag gaatggatat
    88561 ggaacaattg tagctaaagg aatatcaggg cataaagttg attttaagtt aaatgatact
    88621 tttagagatg aaaaagattt acatactaat aaacaaaaaa attatataga ttttcgttca
    88681 ggagttccag aattaaaact atttccacgc aaagaatttt caaagctata taaacaaata
    88741 ctgtatgatt tatcagattc ggatttcaga tatggaagta cagctggtgt atgggtttta
    88801 agagtggaaa tatctaagta tttatttcgt actagaggaa ttagatgtaa tcccaaaaac
    88861 attatgattg tttctggttc aacacaaggt ttatctttaa tttcacagct tttatacaaa
    88921 agtaataaaa aggttgctgt agaagaccct attcataaag gcttattaaa ggttatttca
    88981 tctattggat attcagttgt tggaattaaa gtagatgata agggaatgaa taccaactta
    89041 ataaaatcaa taaaagggat ttcttttgtt tatactacac cttctcatca atacccatta
    89101 ggagggattt tacctattca aagaagacta gagcttatta aatgtgcaac agagaatgat
    89161 tactatataa ttgaagatga ttatgatagt gaatttagat atgagggtca accaattagt
    89221 tctctttatg aacttagccc aaataaagta atttacatag gttcttttag taaaatatta
    89281 tctccagcta ttcgtgttgg atttatgtta ttaccagaca atattttaga aagctataaa
    89341 accttaaaaa tgtactctga tgttcataca gaaacaatat tgcaacatgt attagctgaa
    89401 tttattggaa atggaggttt agagaagtac atatttagaa tgaagaagtt gtacaataga
    89461 aaacgtaagt acctcataaa agttttaaac acggaattta aaaatgaatt taaaataaaa
    89521 ggtgaagcag cagggcttca tatagttgct catttctata atgttaaatt tacggaaagt
    89581 ttaattcata aaatttttga agcaggtata aaagtttatc ctatacaaca atatgcaatt
    89641 gagaatatat tagaatatga ccatgaaatt atactaggtt atgctcatct tagttttgat
    89701 gaaattgaaa aaggtgtaaa aatactcagc aaaataatac atatgaatca aggtacatag
    89761 ataaaacata tagcaatcta catataatag atgtaattaa gtttaaactt taaaagaaat
    89821 atatattaat atttttgtat aaaaatacct gatatttttt tatcgatact ttattgctat
    89881 acactaaatt aagatagcaa tttatattaa gaaaaaactt tttgcatagg ttataatact
    89941 taaaaggaga ggatagagtt gaaaacaaat acagatgtta ttatggagat aattgattat
    90001 atagaagaaa atcttacaga aaatctaaat ttagataaaa tagcttatat tgctaattat
    90061 tcaaaatacc atttacacag aatgtttaca aatgttgtag gatgtactat ccatcaatac
    90121 atacagagga ggagacttac tgaagcagct agacaactta tatttacaga caaatatatt
    90181 atagacatag ctattacagt aggatattct acacatcaat cttttacact agcatttaga
    90241 aatttatata aagaatctcc acaagtatat agaaataaag atgaatttta tcctattcaa
    90301 cagagatttg ttttaaatct aaatcatcaa attcaaagcg aaaaatgtat ttcttatgca
    90361 aatatgaatt ataaacaaag aagagatgaa atcaattctt atctgaactt taatattaat
    90421 tgtgaggtga aagtagcatg agtttagtgc cacatgtaat tgaacaaaca ggtcaagggg
    90481 aaaggtctta tgatatatat tcaaaattat taaaagatag aattatattt ataggagaag
    90541 aaattaatga tgctattgca agtttagtag tagctcaatt actgttttta gaatcagaag
    90601 acccagattc agatataatt atatatataa atagccctgg tggctctgct acatcaggat
    90661 ttgctatata tgatactatg aattatgtca gatgtgatgt atcgactatt tgtattggta
    90721 tggctgcaag catgagtgct tttttacttg caggaggaac acatggaaaa agatgtgctt
    90781 tacccaattc agagattatg attcatcagc caatgggagg agctaaaggt caagcaactg
    90841 atgtaaaaat agctgtagat aatatattga aaataaaaga acgattagat aaaattcttt
    90901 ctgaaaatac aggtaaatca atagaagata ttaggagaga tacagataga gataatttta
    90961 tgactgcact agaggctaaa gagtacgggc tgattgatta tataatgaat aggaatgaat
    91021 aaagtatcaa agtatcatat taaaatgtct gttttacaag tatatatata atattaaata
    91081 agagtgtctc aaaatgaact ttttaattta tgggacactc ttttttgtat gaaattaaat
    91141 atggttttat catttcaaca attattacca aatttcaagt ttaataaatt ctactataaa
    91201 aaatacataa aagataaggt tctttagtaa ctttctgtcg tcaaaagttt ttataaattt
    91261 aataacaaaa caagagaaaa taccatatat tacttatgtc tgcaatatat agaagacaaa
    91321 ggagttgtac attatgatta caataagttt gtgcatgatt gttaagaatg aggaagaagt
    91381 tataggcaga tgcttagaat gtgtaaagga tatagtagac gaaattataa ttgtagatac
    91441 cggttctaca gattccacaa aagaaatagt ctcaaaatat acagacatgg tgtacgattt
    91501 cgaatggata gatgatttct ctgctgcaag aaatttttca ttttctaaag cttctaaaga
    91561 ctatactatg tggcttgatg cagatgacat aattttagaa gctgatagag aaaaattatt
    91621 aaagattaaa gaaagcttgg atacttccat tgatattgtt atggcaaaat acaatgtatc
    91681 ctttgatgaa aatggtaacc caactctctc gtattataga gaacgattgt ttaaaagaag
    91741 ttctaatcat aaatgggttg accctattca tgaagtagta cctctttttg gagaggtatt
    91801 ttattctgac attgcaatat ctcataaaaa gcttcataga caggaccctc taagaaatct
    91861 tagaattttt gaaaaaatga tttcagaagg aaaaacattg gagccaagac accaattcta
    91921 ttattctaga gagttgtact ataatgctag gtataaagaa gcaatagaag gttttactaa
    91981 gtttttagac tcatcaagag gatggattga ggattgtatc agtgcttgca gagatttagc
    92041 cacatgttat tacttaatta atgatgaaaa aagtgcatta tattcattgt ttagaagttt
    92101 cgaatttgat gagccaagag cagaaatttg ttgtgacata ggaaagcata tgtttgatag
    92161 acaaaaatat aaagaagcca ttttttggta taaggtagca ttaacaagag ataagaatga
    92221 tactaatgga ggttttaagt caaatgattg ttatggatat ataccatcta tacaattaag
    92281 tgtctgttat gacaggttag gagaatcaga taaagctatt tattatcatg aaaaaacaaa
    92341 agaaatcaaa cctaacgata gtgctgtttt gcacaatgaa aattatttta gtaaatttaa
    92401 aaatagttga taggtcacaa tcatactaaa tttgacatat tatatataga gcttaaaagc
    92461 tcaaatatat caggaggtgc ttttaataat gagtagaaat aaatattttg gaccatttga
    92521 tgataatgat tacaacaatg gctatgataa atatgatgat tgtaacaatg gtcgtgatga
    92581 ttataatagc tgtgattgcc atcattgctg tccaccatca tgtgtaggtc caacaggccc
    92641 aatgggtcca agaggtagaa ccggcccaac aggtccaacg ggtccaacag gtccaggagt
    92701 aggggcaaca ggcccaacag gaccaaccgg tccgactggc ccaacaggaa atacagggaa
    92761 tacaggagca acaggattaa gaggtccaac aggagcaaca ggggcaacag gcccaacagg
    92821 agcgacagga gctatagggt ttggagtaac aggtccaaca ggcccaacag gagcgacagg
    92881 agcaacagga gcagatggag taacaggtcc aacaggtcca acgggagcaa caggagcaga
    92941 tggaataaca ggtccaacag gagcaacagg ggcaacagga tttggagtaa caggtccaac
    93001 aggcccaaca ggagcaacag gagtaggagt aacaggagca acaggattaa taggtccaac
    93061 aggagcaaca ggaacacctg gagcaacagg tccaacaggg gcaataggag caacaggaat
    93121 aggaataaca ggtccaacag gagcaacagg agcaacaggg gcagatggag caacaggagt
    93181 aacaggccca acaggcccaa caggggcaac aggagcagat ggagtaacag gcccaacagg
    93241 agcaacagga gcaacaggaa taggaataac aggcccaaca ggtccaacag gagcaacagg
    93301 aataggaata acaggggcaa caggattaat aggtccaaca ggggca
//
LOCUS       DAEOTL010000006        87562 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEOTL010000006 DAEOTL010000000
VERSION     DAEOTL010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 87562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87562
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.006"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            95..970
                     /locus_tag="KRH82_000627"
     CDS             95..970
                     /locus_tag="KRH82_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HBG8653923.1"
                     /translation="MNVYEKGNGVILERVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            988..2478
                     /gene="cls"
                     /locus_tag="KRH82_000628"
     CDS             988..2478
                     /gene="cls"
                     /locus_tag="KRH82_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBG8653924.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            2671..2955
                     /locus_tag="KRH82_000629"
     CDS             2671..2955
                     /locus_tag="KRH82_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBG8653925.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            2988..4616
                     /gene="groL"
                     /locus_tag="KRH82_000630"
     CDS             2988..4616
                     /gene="groL"
                     /locus_tag="KRH82_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBG8653926.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            4878..5618
                     /gene="larB"
                     /locus_tag="KRH82_000631"
     CDS             4878..5618
                     /gene="larB"
                     /locus_tag="KRH82_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBG8653927.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEVSK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            5702..6436
                     /gene="larC"
                     /locus_tag="KRH82_000632"
     CDS             5702..6436
                     /gene="larC"
                     /locus_tag="KRH82_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBG8653928.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKFKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            6466..6885
                     /locus_tag="KRH82_000633"
     CDS             6466..6885
                     /locus_tag="KRH82_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBG8653929.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      6945..7046
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            7267..8802
                     /gene="guaA"
                     /locus_tag="KRH82_000634"
     CDS             7267..8802
                     /gene="guaA"
                     /locus_tag="KRH82_000634"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBG8653930.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            9341..10771
                     /locus_tag="KRH82_000635"
     CDS             9341..10771
                     /locus_tag="KRH82_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8653931.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVSIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(10919..11794)
                     /locus_tag="KRH82_000636"
     CDS             complement(10919..11794)
                     /locus_tag="KRH82_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8653932.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETALFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISHLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSKQALSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLLHKKLRLIELDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            11914..12477
                     /locus_tag="KRH82_000637"
     CDS             11914..12477
                     /locus_tag="KRH82_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBG8653933.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVIAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            12474..13040
                     /locus_tag="KRH82_000638"
     CDS             12474..13040
                     /locus_tag="KRH82_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBG8653934.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKM
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(13169..13405)
                     /locus_tag="KRH82_000639"
     CDS             complement(13169..13405)
                     /locus_tag="KRH82_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8653935.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(13715..17143)
                     /gene="uvrA"
                     /locus_tag="KRH82_000640"
     CDS             complement(13715..17143)
                     /gene="uvrA"
                     /locus_tag="KRH82_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBG8653936.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSIGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKIIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSKC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            17462..19696
                     /locus_tag="KRH82_000641"
     CDS             17462..19696
                     /locus_tag="KRH82_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8653937.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTVSYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGKGTIEIINSKGKPLFIGKNTELIKDLSHKYKSSGDEP
                     WAQKMLEDFKNDKSGNITITSSKGVQCLLTYHPITRGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENLEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            19952..21982
                     /locus_tag="KRH82_000642"
     CDS             19952..21982
                     /locus_tag="KRH82_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8653938.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            21979..22431
                     /locus_tag="KRH82_000643"
     CDS             21979..22431
                     /locus_tag="KRH82_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8653939.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            22433..23488
                     /locus_tag="KRH82_000644"
     CDS             22433..23488
                     /locus_tag="KRH82_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBG8653940.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            23555..23863
                     /locus_tag="KRH82_000645"
     CDS             23555..23863
                     /locus_tag="KRH82_000645"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBG8653941.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            23967..25232
                     /locus_tag="KRH82_000646"
     CDS             23967..25232
                     /locus_tag="KRH82_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBG8653942.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            25320..26036
                     /locus_tag="KRH82_000647"
     CDS             25320..26036
                     /locus_tag="KRH82_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBG8653943.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(26231..26524)
                     /locus_tag="KRH82_000648"
     CDS             complement(26231..26524)
                     /locus_tag="KRH82_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBG8653944.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(26530..26745)
                     /locus_tag="KRH82_000649"
                     /pseudo
     CDS             complement(26530..26745)
                     /locus_tag="KRH82_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(27157..27669)
                     /locus_tag="KRH82_000650"
     CDS             complement(27157..27669)
                     /locus_tag="KRH82_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8653945.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            28119..28595
                     /gene="purE"
                     /locus_tag="KRH82_000651"
     CDS             28119..28595
                     /gene="purE"
                     /locus_tag="KRH82_000651"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBG8653946.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            28601..29299
                     /locus_tag="KRH82_000652"
     CDS             28601..29299
                     /locus_tag="KRH82_000652"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBG8653947.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            29311..30678
                     /gene="purF"
                     /locus_tag="KRH82_000653"
     CDS             29311..30678
                     /gene="purF"
                     /locus_tag="KRH82_000653"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBG8653948.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            30672..31748
                     /locus_tag="KRH82_000654"
     CDS             30672..31748
                     /locus_tag="KRH82_000654"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBG8653949.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            31742..32335
                     /locus_tag="KRH82_000655"
     CDS             31742..32335
                     /locus_tag="KRH82_000655"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBG8653950.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKIKLQGRRVFINE"
     gene            32328..33860
                     /gene="purH"
                     /locus_tag="KRH82_000656"
     CDS             32328..33860
                     /gene="purH"
                     /locus_tag="KRH82_000656"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBG8653951.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            33871..35121
                     /gene="purD"
                     /locus_tag="KRH82_000657"
     CDS             33871..35121
                     /gene="purD"
                     /locus_tag="KRH82_000657"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBG8653952.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            35146..38952
                     /locus_tag="KRH82_000658"
     CDS             35146..38952
                     /locus_tag="KRH82_000658"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBG8653953.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            39158..40030
                     /gene="rfbD"
                     /locus_tag="KRH82_000659"
     CDS             39158..40030
                     /gene="rfbD"
                     /locus_tag="KRH82_000659"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBG8653954.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            40139..41008
                     /gene="rfbA"
                     /locus_tag="KRH82_000660"
     CDS             40139..41008
                     /gene="rfbA"
                     /locus_tag="KRH82_000660"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBG8653955.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGINITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            41057..41614
                     /gene="rfbC"
                     /locus_tag="KRH82_000661"
     CDS             41057..41614
                     /gene="rfbC"
                     /locus_tag="KRH82_000661"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBG8653956.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            41652..42635
                     /gene="rfbB"
                     /locus_tag="KRH82_000662"
     CDS             41652..42635
                     /gene="rfbB"
                     /locus_tag="KRH82_000662"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBG8653957.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVNSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKVILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            42665..43333
                     /locus_tag="KRH82_000663"
     CDS             42665..43333
                     /locus_tag="KRH82_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBG8653958.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            43342..43770
                     /locus_tag="KRH82_000664"
     CDS             43342..43770
                     /locus_tag="KRH82_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBG8653959.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            43794..44108
                     /locus_tag="KRH82_000665"
     CDS             43794..44108
                     /locus_tag="KRH82_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBG8653960.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            44260..44535
                     /gene="flgM"
                     /locus_tag="KRH82_000666"
     CDS             44260..44535
                     /gene="flgM"
                     /locus_tag="KRH82_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBG8653961.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            44540..44956
                     /locus_tag="KRH82_000667"
     CDS             44540..44956
                     /locus_tag="KRH82_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBG8653962.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKKTTTYNSYGNIRK"
     gene            44974..46284
                     /gene="flgK"
                     /locus_tag="KRH82_000668"
     CDS             44974..46284
                     /gene="flgK"
                     /locus_tag="KRH82_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBG8653963.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            46303..47235
                     /gene="flgL"
                     /locus_tag="KRH82_000669"
     CDS             46303..47235
                     /gene="flgL"
                     /locus_tag="KRH82_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBG8653964.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            47251..47643
                     /locus_tag="KRH82_000670"
     CDS             47251..47643
                     /locus_tag="KRH82_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBG8653965.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            47637..47849
                     /gene="csrA"
                     /locus_tag="KRH82_000671"
     CDS             47637..47849
                     /gene="csrA"
                     /locus_tag="KRH82_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBG8653966.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            47871..48266
                     /gene="fliS"
                     /locus_tag="KRH82_000672"
     CDS             47871..48266
                     /gene="fliS"
                     /locus_tag="KRH82_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBG8653967.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            48266..48622
                     /gene="fliS"
                     /locus_tag="KRH82_000673"
     CDS             48266..48622
                     /gene="fliS"
                     /locus_tag="KRH82_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBG8653968.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            48643..50166
                     /gene="fliD"
                     /locus_tag="KRH82_000674"
     CDS             48643..50166
                     /gene="fliD"
                     /locus_tag="KRH82_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBG8653969.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            50169..50504
                     /gene="fliT"
                     /locus_tag="KRH82_000675"
     CDS             50169..50504
                     /gene="fliT"
                     /locus_tag="KRH82_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBG8653970.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            50606..51478
                     /locus_tag="KRH82_000676"
     CDS             50606..51478
                     /locus_tag="KRH82_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBG8653971.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            51571..53712
                     /locus_tag="KRH82_000677"
     CDS             51571..53712
                     /locus_tag="KRH82_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBG8653972.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            53736..55613
                     /locus_tag="KRH82_000678"
     CDS             53736..55613
                     /locus_tag="KRH82_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBG8653973.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            55606..57720
                     /locus_tag="KRH82_000679"
     CDS             55606..57720
                     /locus_tag="KRH82_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBG8653974.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            57729..58724
                     /locus_tag="KRH82_000680"
     CDS             57729..58724
                     /locus_tag="KRH82_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBG8653975.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            58816..60048
                     /locus_tag="KRH82_000681"
     CDS             58816..60048
                     /locus_tag="KRH82_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBG8653976.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            60068..61012
                     /locus_tag="KRH82_000682"
     CDS             60068..61012
                     /locus_tag="KRH82_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBG8653977.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            61106..61513
                     /locus_tag="KRH82_000683"
     CDS             61106..61513
                     /locus_tag="KRH82_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBG8653978.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            61600..62691
                     /locus_tag="KRH82_000684"
     CDS             61600..62691
                     /locus_tag="KRH82_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBG8653979.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      63000..63090
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            63500..63817
                     /gene="flgB"
                     /locus_tag="KRH82_000685"
     CDS             63500..63817
                     /gene="flgB"
                     /locus_tag="KRH82_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBG8653980.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMTTLQYNALISFANGKIAMTKSII
                     SGR"
     gene            63825..64229
                     /gene="flgC"
                     /locus_tag="KRH82_000686"
     CDS             63825..64229
                     /gene="flgC"
                     /locus_tag="KRH82_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBG8653981.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKKVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            64239..64553
                     /gene="fliE"
                     /locus_tag="KRH82_000687"
     CDS             64239..64553
                     /gene="fliE"
                     /locus_tag="KRH82_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBG8653982.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNKEEKKNFEDVIIDTID
                     KVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNKV
                     QI"
     gene            64578..66128
                     /gene="fliF"
                     /locus_tag="KRH82_000688"
     CDS             64578..66128
                     /gene="fliF"
                     /locus_tag="KRH82_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBG8653983.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTSGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVNENNQPINSGISVDKNKASEQALNKQLEKSILEILEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            66141..67211
                     /gene="fliG"
                     /locus_tag="KRH82_000689"
     CDS             66141..67211
                     /gene="fliG"
                     /locus_tag="KRH82_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBG8653984.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSMSGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAAEALREEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            67204..67935
                     /locus_tag="KRH82_000690"
     CDS             67204..67935
                     /locus_tag="KRH82_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBG8653985.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYNEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            67939..69258
                     /gene="fliI"
                     /locus_tag="KRH82_000691"
     CDS             67939..69258
                     /gene="fliI"
                     /locus_tag="KRH82_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBG8653986.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVYATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRGIFE"
     gene            69290..69736
                     /gene="fliJ"
                     /locus_tag="KRH82_000692"
     CDS             69290..69736
                     /gene="fliJ"
                     /locus_tag="KRH82_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBG8653987.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSIGKNNDSVQNQKITINYLLALNNSIMDLSEKLDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            69764..70969
                     /locus_tag="KRH82_000693"
     CDS             69764..70969
                     /locus_tag="KRH82_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBG8653988.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNDKFEDNLYKTTDHKKV
                     KDRRETSKQNVSSDRPENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            70987..71595
                     /locus_tag="KRH82_000694"
     CDS             70987..71595
                     /locus_tag="KRH82_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBG8653989.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            71622..72605
                     /locus_tag="KRH82_000695"
     CDS             71622..72605
                     /locus_tag="KRH82_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBG8653990.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            72618..72821
                     /locus_tag="KRH82_000696"
     CDS             72618..72821
                     /locus_tag="KRH82_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBG8653991.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            72821..73639
                     /locus_tag="KRH82_000697"
     CDS             72821..73639
                     /locus_tag="KRH82_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBG8653992.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            73629..74324
                     /locus_tag="KRH82_000698"
     CDS             73629..74324
                     /locus_tag="KRH82_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBG8653993.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            74336..74779
                     /locus_tag="KRH82_000699"
     CDS             74336..74779
                     /locus_tag="KRH82_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBG8653994.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            74794..75168
                     /locus_tag="KRH82_000700"
     CDS             74794..75168
                     /locus_tag="KRH82_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBG8653995.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEVLKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            75169..75834
                     /gene="fliP"
                     /locus_tag="KRH82_000701"
     CDS             75169..75834
                     /gene="fliP"
                     /locus_tag="KRH82_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBG8653996.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            75847..76116
                     /gene="fliQ"
                     /locus_tag="KRH82_000702"
     CDS             75847..76116
                     /gene="fliQ"
                     /locus_tag="KRH82_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBG8653997.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            76128..77942
                     /locus_tag="KRH82_000703"
     CDS             76128..77942
                     /locus_tag="KRH82_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBG8653998.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYSVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFNMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            77951..80026
                     /gene="flhA"
                     /locus_tag="KRH82_000704"
     CDS             77951..80026
                     /gene="flhA"
                     /locus_tag="KRH82_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBG8653999.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            80001..81017
                     /gene="flhF"
                     /locus_tag="KRH82_000705"
     CDS             80001..81017
                     /gene="flhF"
                     /locus_tag="KRH82_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBG8654000.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDAM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            81014..81892
                     /locus_tag="KRH82_000706"
     CDS             81014..81892
                     /locus_tag="KRH82_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBG8654001.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNVISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            81906..82607
                     /locus_tag="KRH82_000707"
     CDS             81906..82607
                     /locus_tag="KRH82_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBG8654002.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            82623..83045
                     /locus_tag="KRH82_000708"
     CDS             82623..83045
                     /locus_tag="KRH82_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBG8654003.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            83030..83215
                     /locus_tag="KRH82_000709"
     CDS             83030..83215
                     /locus_tag="KRH82_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBG8654004.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            83256..84029
                     /gene="flgG"
                     /locus_tag="KRH82_000710"
     CDS             83256..84029
                     /gene="flgG"
                     /locus_tag="KRH82_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBG8654005.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            84050..84811
                     /gene="flgG"
                     /locus_tag="KRH82_000711"
     CDS             84050..84811
                     /gene="flgG"
                     /locus_tag="KRH82_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBG8654006.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGKDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            84834..85715
                     /locus_tag="KRH82_000712"
     CDS             84834..85715
                     /locus_tag="KRH82_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBG8654007.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDIGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            85718..86092
                     /locus_tag="KRH82_000713"
     CDS             85718..86092
                     /locus_tag="KRH82_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBG8654008.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            86124..87527
                     /locus_tag="KRH82_000714"
     CDS             86124..87527
                     /locus_tag="KRH82_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBG8654009.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISSGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDEAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFERYNQLIRLINRGMYKEAIQGFKLITEQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
BASE COUNT        35084 a         9249 c        15871 g        27358 t
ORIGIN      
        1 tctttgtgtt aaaataagta aaatgcacat attagagcta agtttttaag taaataaaca
       61 aaatgaaaat ataaatatta aggagatttg gtatatgaat gtttatgaaa aaggtaatgg
      121 agttatacta gaaagagtaa cagattttga cccagtacat atatttgagt gtggtcaatg
      181 ttttagatgg cacaaacaag aagatggctc atacactgga gttgcaaagg ggagaatatt
      241 aaatgtcaaa aaagagaatg ataaaatata tttaaataat actaatttaa aggagtttaa
      301 cagcatttgg tataattact ttgatttagg aactgattat acagaaataa agaataagct
      361 aaaaaatatg gatgaatatt taaataaggc tactgaattt ggatggggaa taagaatatt
      421 aagacaagat ggatgggaaa tgcttatatc atttataatt tcctctaata ataggattcc
      481 tatgatacaa agagcgatag aaaatttatc aagaaagttt ggtaagtata taggtgaata
      541 tgaaggtaat gaatactatg cattcccaac accagaagaa ctaaataagg cctcacaaga
      601 ggaaataaga gcatgtcaaa caggttttag agataagtac ataaaaagta ctacacaggc
      661 agttatagag aataatgatg aggtatctga atatacaaat ttaagtacag aggattgtag
      721 aaaagagctt ttaaaattta atggagtagg accaaaagta tgtgattgta ttgcattatt
      781 tggtatgcaa aaatatgatt cttttccagt tgatgtttgg gttaagagag ttatgcaaga
      841 attttatata gatgaagaca tgagtttacc taaaatgaga acttatggaa tcgataaatt
      901 taaagaaatg tctggatttg ctcaacagta cttattttac tatgcaagag aactcggtat
      961 aggaaaataa attaaggggg agaaattatg ggagtaatag gaacaatatt tctgttctat
     1021 ttaattatat catatctagc tggagccata atttctgtga ttatattact tgaaaataga
     1081 gaccctgcaa aaacaatgtc ttggctattg atgtttatta tatttccagg tgtaggttta
     1141 atgatatatg ctatttcagg tagaaatatt agaaaaagaa aattatttaa gactcaaaaa
     1201 ctagctaata atataaaaga aaagaaacta tttgatacat tagaaaagat aacagaaata
     1261 gttgaattag aaaaagaatc tataaaacaa aataagcttt taagagatga agaggatggt
     1321 agttatagaa aaagggtaat aaatatgttg ttaaagactg gtatgtttcc ctttactaaa
     1381 aataataaag tggatgtatt tgtagatgga aatgaaaagt ttaaaagact tatagaagat
     1441 ataagagaag ctaaagacca tattcattta gagtacttta tcatcaaaga tagtgaaata
     1501 ggtagggtgt taaaagaaga acttataaaa aaggctaaag aaggcattaa gataagaatt
     1561 ttatatgatg atgtaggatg ctggagattt tggtttaata gaaaattttt ccgagaaatg
     1621 agggaagtag gtatagaaat tgcagcattt ttacctacaa aatttcctat aataggaggg
     1681 aaattaaact atagaaatca cagaaaaatt gttgttattg atggaataat tggatataca
     1741 ggtggaataa atataggaga tgaatattta ggcaaaaatg ataagtttgg atattggaga
     1801 gatactcata ttaggattaa gggtatttct gtatacatgc ttcaaatgac atttctgatt
     1861 gattggtatt atacaacaaa agaagtatta gtgactaaaa attatttccc aagtgtaggg
     1921 aatgttggtg aaagtatgat acaagttgtt gcgagtggtc cagacagtga ctgggaagat
     1981 attcattatg cttatttttc tgcaatatgt caggctagaa aaaatgttta tatagaaact
     2041 ccatatttta ttccagatga aagtctacta aaagctataa agagtgctgc tcttagtgga
     2101 gttgatgtga gaataatatt tcctaaaatt gcagaccaca agatagtaaa tatagcatct
     2161 tattcatatt ttgaagaaat attaagagca ggtggtaaag tttatttata taataaagga
     2221 tttatacatt ctaaagtcgt aataatagat gataaaattg cttctgcagg tacagctaat
     2281 atggatttaa gaagttttat gcttaacttt gaggtaaatg catttatcta tgatgaagaa
     2341 gttattaggg taatgacaga tgatttcttt gaggatttaa gtcactgtga agaacttaat
     2401 ttggaggtat ttaagaatag aaatatcata caaaaaatca aagaatctgt agcaagatta
     2461 ttttcaccaa tattataaaa aattattaaa aaaggtattg aaaattatgt gtgattggta
     2521 tattataata attgttagca ctctattaga tagagtgata ataaataaaa agtatatata
     2581 taaatctaca tatataagta gtattaattt aaaaataact aaaaacatag gcgaactagt
     2641 ctatacttaa tattttagga ggcgttaata atgaaaataa gaccattagc tgacagagta
     2701 gtaattaaaa aagtagaagc agaagaaaaa actgcaagtg gaatagtttt accaggagca
     2761 gctaaagagc aacctcaaat agctgaagtt gtagaagttg gaccaggtgg aatagttgaa
     2821 gggaaagaaa taaaaatgga attgacagtg ggagataagg ttatattcca aaaatattct
     2881 ggaacagaag ttaagataga aggacaagaa tacacaatac taagacagag tgatgtatta
     2941 gctgttattg aataaatata gaataaattt attaggaggg gtttaaaatg gctaaagaaa
     3001 ttaaattttc agaggaaaca agaagagctt tagaagctgg tgtaaataaa ttagcagata
     3061 cagtaaaagt aacattagga cctaaaggaa gaaatgttat attagataaa aaatttggtt
     3121 ctccacttat aactaatgat ggagtaacta tagcaaaaga gatagaacta gaagatagat
     3181 ttgaaaatat gggtgctcaa ttagttaaag aagtagcaac taaaactaat gatgtagctg
     3241 gagatggtac tacaactgct acagttttag cacaagctat aataagagaa ggtttaaaga
     3301 atgtaacagc aggggctaac ccaatacttt taagaaaagg aatacaaaaa gcagtaacag
     3361 tagcagtaga agaattaaaa aatcaatcaa gaatagtaga aacacaagag gctatatctc
     3421 aagttgcttc tatatctgct ggtgatgaag aagttggaaa attaatagca gaagctatgg
     3481 aaatagtagg taaagatgga gttataactg ttgaagagtc tcaaactatg aatactgaat
     3541 tagatgctgt tgaaggtatg cagtttgata gaggatttgt ttctgcatat atggttacag
     3601 atgtagataa aatggaagca gttttaaatg acccatatat attaattact gataaaaaaa
     3661 tatctaacat acaagaatta ttaccagttc ttgaacaaat agttcaacaa ggtaaaaagt
     3721 tattgataat agctgaagat gtagaaggtg aagcattatc tacattagta gtaaataaat
     3781 taagaggaac atttgatgta gtagcagtta aagctccagg ctttggagat agaagaaaag
     3841 aaatgcttca agatatagca atacttacag gtgctcaagt aatatcagaa gaattaggtt
     3901 atgatttaaa agaagctgat ttatctatgc taggtagagc ttcatctgtt aaggtaacta
     3961 aagaaagtac tacaatagta gatggttctg gagataaaaa agctatagaa gatagagtaa
     4021 ctcaaattaa acatcaagta gagcaaacta cttcagattt tgatagagag aaattaatgg
     4081 aaagattagc taaacttgct ggaggagtag ctgttgtaaa agttggagct gctacagaag
     4141 tagagttaaa agaaagaaag ttaagaatag aagatgctct taatgcaact agagcagctg
     4201 tagaagaagg aatagtagct ggtggaggaa ctgcttttgt tagtgttata ccagcaatag
     4261 gaacactaat tgagagttta gaaggagaag ttaaactagg tgctcaaata gttaaaaaag
     4321 cgttagaaga gccattaaga caaatagcta taaatgctgg tcttgaaggt gctgtaattg
     4381 tgcaaaatgt tgttaattct gaagcagaaa ctggatttga cgcattgaat gaaaaatatg
     4441 taaatatgat agaagctggt atagttgacc caactaaagt tagtagaagt gctttacaaa
     4501 atgctgcatc aatagcaagt actttcttaa ctactgaagc tgctgttgct gaccttcctg
     4561 aaaaagaaga tgcaggaatg ccaggaatgg gtggcggaat gcctggtatg atgtaattta
     4621 aaaaatttaa aatataaatt ttaatataaa gaactatttc gacttagatt ttaaactcta
     4681 agttgaaata gttcttttgt atatatctaa tttttgtata tctataaatt caatacacat
     4741 atttagataa tcagtatcta gtttgtaata atattttaga gtagtattgt tattttttag
     4801 gttatgattt tagatatata ttaattaagg tataattgtt gatagagaat aaatcaaatt
     4861 taaaaggatg cgataatatg gacttaagaa aattgcttga agaagttaaa aatgaaaata
     4921 ttgatataga ttttgcgtta gaaaagttaa aagatttacc ttatgaagac cttggatatg
     4981 caaatataga ccatcataga gaattaagaa atgggtatcc ggaagttatt tattgtgaag
     5041 gtaagagtga tgagcatatt ttagggatta ttgataaaat gaatcaaaaa agttctaaca
     5101 tattggggac aaggtgcaga aaagaaactt ttctgaaaat taaagaaatc tataatcatg
     5161 ctgagtatga agaggtgtct aaaattctta agattcaaaa tcatgatata gagaatatag
     5221 gaaaaggtaa aattgtgatt gctacagggg gaacttctga tataccagta gcagacgaag
     5281 cttatcatac agctaagttt ttaggtaatg atgttgatag aatatatgat gttggagtgg
     5341 caggtataca taggctttta aataaaagac ataaaataga tagtgctaga gtaatagtag
     5401 ccgttgcagg tatggaaggt gctcttgcaa gtgtaattgg tggactggtt gatgttccag
     5461 taatagctgt tccaacttct gttggatatg gagcaaattt tggaggatta gcagcattac
     5521 tagctatgtt aaatagctgt gcatctggaa tatctgttgt aaatattgat aatggatttg
     5581 gagcaggata tttagcatca atgataaata aactgtaaat acattgatat aaattaaaca
     5641 aaactatata ataaaattta atttctatta tatttttact attaaaattg aggagacata
     5701 tatgagtgaa aaaatacttt attttgatat aataagcggt atatcagggg atatgaccct
     5761 tgcaagttta ttaaatttag gtgtgcctaa ggaaattttt ttggaggaaa ttcataaact
     5821 aagaatgagc gatgaattta atataaacat cagctcgaaa actgaaaatg gaatagtagg
     5881 tacaaaagta gaagtaatta caaaagaaaa acatacgcat agaaatttag tggatatatt
     5941 tgaggttata gataaaagca ctctaaacga aaatgtaaaa tttaaagcaa aaaaaatatt
     6001 tatggtaatt ggagaagcag aagcaaaagt tcatggaact acaatagaca agatacattt
     6061 tcatgaggta ggggctatag attcaattgt agatatagta ggagcttcta tattagttga
     6121 cttactttgt gtagataaag tttgtgctag tacagtgtct gttggttcag gatttgtaaa
     6181 atgtgaacat ggaattatac ctatacctgc acctgcaact atagaaattt taaaaggtgt
     6241 gccaattaaa ttaaataatg taaatggaga atgtacaact ccaacaggag ctgcaatcat
     6301 aaaagtcttg tgtgatgagt ttgtagatga gcttgaattt tctccaaagc aaattggata
     6361 tggtataggt cataagaagt ttgaagtacc aaatatactc agaactgtat taggtgaaaa
     6421 aaaaaagaag aattaattta tgaaattagt gcaaacattg atgatatgtc ttcagaaatc
     6481 tattcttatt tgtatgaaaa aatattagat gagaaagcat tagatattta tacagagagc
     6541 atttatatga agaagaatag accagcaaca aaagtatcaa ttttatgtaa tgaatcagat
     6601 ttagaaaaat ttattaaaat attactttta gaaactagta cttttggagt gagatataat
     6661 gcatataata gagaaattct agagagaaaa tttgtaaaat tagatacaaa atatggagtg
     6721 gttacagtaa aactagggta ttataaagga aaactagtca aggctactcc agaatataat
     6781 gaatgtaaaa ctatagcaaa aaatgaagat attcctataa aaaaagtgtt tgctgatata
     6841 aattttagaa taaaagaaga atttagtgaa aacttattga cataagtaat aaattttgat
     6901 aaattaatat tcagccttat taaataaaag taaacagaaa aaaatatata aaatataaac
     6961 tcactcgtat atgctcagaa atatggtctg agagtctcta ccaagatacc gtaaatatct
     7021 tgactatgag tgaaattatt ataccaaaag acctagttaa gtaaatgtgt aggctgagtt
     7081 aaactcccta tgtgttggct ataagataaa ggtattttgg aagcctgtat agtaatttca
     7141 cttttgctag aaattatgga agttactata caggtttttt gtgtaaaaag atttaatata
     7201 atttagactg tattgtgtta aaataaatat ataaaaacta tattatacaa ggagagatgt
     7261 aaatttatga aacatgaatt agtacttgta atagattttg gaggacaata taatcagttg
     7321 atagctagaa gagttagaga aaacaacgta tattgtgaaa tacttccatg tactgcaagc
     7381 atagaaagaa taaaagaaaa aaatcctaaa gggataatat ttacaggcgg tccaaatagt
     7441 gcgtatttag aagattctcc aacaatatca aaagaaatat ttgaactagg agtaccaata
     7501 cttggaatat gctatggtat tcaaataatg tctcatgtat tgggtggagt tgtaagaaaa
     7561 ggtaataaac aagaaaaaga atatggaaaa acagctataa cttatggaaa atcatcatta
     7621 tttgaaggaa taactacaaa tagtgtatgg atgagtcata cagatttaat agaaaaagtt
     7681 ccagaaggat ttactatagt tgcaaatact aatgattgtc cagtagcagc tatggaaaat
     7741 gtagaacgaa acctatatgg agttcaattc catccagagg tagaacactg tttggaaggg
     7801 gacaagatac ttacaaactt cttatataat atttgtaaag taaaaggtga ctggactaca
     7861 gattcattca tagaagataa aataaaagaa ttaaaagaaa aaataggcga taaaaaagct
     7921 ttatgtgctt taagtggagg agttgattct tctgttgctg cagttcttat tcataaagca
     7981 attggggaca acttaacttg tatatttgtt gaccatggtt tacttagaaa aaatgaagga
     8041 aatgatgtag aaagaatatt tagagagaaa tttgatataa atttaataag agttaatgca
     8101 gaagatagat tcttatctaa attaaaagga gtttctgaac cagaagctaa gagaaaaata
     8161 ataggtgaag aatttataag agtatttgaa gaagaatcaa ataaattagg aaaaatggat
     8221 ttcttagtac aaggaacaat ctatccagat gttatagaaa gtggacatgg aaatgctgct
     8281 actataaagt ctcatcataa tgttggtgga atcccagaag atgtagactt ccaagaaatt
     8341 gtagaaccat taagagagtt atttaaggat gaagttagaa aaataggatt agagcttggt
     8401 atagaagaag gattaatatt tagacatcct ttcccaggac caggtctagg aataagagtt
     8461 ataggtgatg taactaaaga aaaatgtgat atattaagag aagctgatgc tgtttatatg
     8521 gacgagctta gaaaagcagg tttatacaga gaaatatggc aagcttttgc aacattacca
     8581 gatgttaaga ctgttggagt tatgggtgat gaaagaacat atgcttattt agttggttta
     8641 agagcagtta cttcttctga tggaatgact tctgactggt ataagatgcc ttatgatgta
     8701 ttagaaagaa tttctaatag aataataaat gaagttgatg gagtaaatag agtagtttat
     8761 gatataactt ctaagcctcc tggaactatt gaatgggaat aaaatataga atgccaaaaa
     8821 tccacataaa tacaggattt gaggtctatc ttacttctat gttatactgg tttgatacta
     8881 tcaatatttg ccagtatctt atggattaat aagtaaaaaa catcctgctg aatgataaat
     8941 tcagcggggt gtttttattt tgttttagaa ctcctttgct ctgaaactcg aagtatttaa
     9001 cactgatgat tttgttatct tttagttcct tttgtgtcat gctctgaaag acaaattgat
     9061 acaataaaaa agtaatttct taatcattga tggagatatg tatttatgtt actcttgatg
     9121 gtaatttgag taatattgtt catagctttt tatattcact taattagaaa accatttggt
     9181 ataatcataa ataaacttga tgatataata gaaaagattt atacttatta gaagtatata
     9241 aaagtatttt atgtctatga aatgtatgtc tataaaacat atagatgact tttgtatatt
     9301 aatgtatgaa tattgatatt atagaagaat tgagttgtca atgatactaa atcaaatatt
     9361 tatagaagct ggagggatta tgagaaataa aataattata ggaattactt tttcacttgt
     9421 attactaatg tctggatgtg cttcaaaaca aaccgcagaa ataaacgtat tagcaactac
     9481 tgatttacat ggagttatac cttatgagtt aacttcttat gtaaaagaag aaagaaaaaa
     9541 agataaaaat ctaactttag tagatgcagg agattttttt gatagtggag aagtgtttgg
     9601 ttctagcatg gatagttatt ttagtgctag atataaagat ggtgataata acactgaaag
     9661 ttatattgag acgcctattt caaaagatat gaaagaggta ggttatgatg ttgcagttct
     9721 tgggaatcat gaatttatat ccaacaataa attttatcta gataatatga tatctgattt
     9781 tgagaagcaa aaaataaata ttttatcggc aaatacgtat aaaaaaaatg gagacagtta
     9841 tacaaaacca tacataataa aaaatattaa tacacctgaa ggaaacgtaa aactaggaat
     9901 tttagggctt actataaaag aagttggtga gaggaaacag tggaaagatg gaaaacttgt
     9961 tgactctaag tctttagaac taaaagacca agagggctac aatggtgaat tgtatatgaa
    10021 tgatttagta gaagatgcta aaaagtgggt tagtataatg gaaaaagaga agcctgacat
    10081 tatagttgct gtggcacata caggtgagaa acctaagaaa cctagaaacc caggaaatag
    10141 aatacaagac ttagctcaac aagttgatgg aattgatgct atagttgcag gtcataatca
    10201 tgttcaaatt gagcaacatg attataaaaa taaatcagga gaaaatgtta tagttactga
    10261 gccaggaaag catggagaat gtatttctaa gattaatttt aaattagaaa aaaacaatga
    10321 taaatggaat atagttgaca aatctagtaa attaattaaa tttgaaaaaa atcaagaaag
    10381 tgataaattt ggagaattta tttcttcaat taataaagta agtaaagata agaaagaaat
    10441 aagattatca gaagtaaaga ctcctgaatg ggataaaata tatgttttta aatctggaac
    10501 atctgcagat gatatatata aaacgatagg atataaatgg agaaatatat catctccaaa
    10561 gggtgatgac atggtgcaga ttgttgtaat gaataataat aagcctgtta gctatgtata
    10621 tggtgaagct gaagttatgc caattaatat aaaatgtgat gaatcagagt ataaagataa
    10681 tgttgtaact atttatccta ataaaaatga taaatttaaa attgaaaaag gtaaacaaga
    10741 atatagtatt aatttaaaac atatacaata gaaactttta tcttatttaa gtttagattg
    10801 tacttaaaat aaagtgtgta ttattttaaa aattgatgat aattaaaatc acaacattaa
    10861 ggaatagtac acacttttta tgctaaaaaa tagaatgtta aaaaattaaa cctttaaatt
    10921 aaagtacatt gcttatatta tccaatatta ttttcaaagg ttgtgtaata tttttatctt
    10981 tatgtaatat tgctaacatt ttattttcca tatctatccc atctaattca atcaatcgca
    11041 attttttatg taagagtgaa tctaataata aattttctgg caaaatggtt atacctaacc
    11101 ctgcttctgc agctttaata agtgcaaaag aattaacact ttcccaaaca ggataagctt
    11161 tttggtttga aagagataat acactgtcca aagtatcgcg aatggcactt ccttgctcac
    11221 gtaacaataa cggaaacgtg cataactgtc gtagagataa ggcttgttta gataaaggaa
    11281 aagttggagc acatgcaaca cataacttat aggaacctaa taaaattgta cggaatgccc
    11341 cctgtggttc tataccttcc caaaagcata tatcagcttc tccacttttt aaaatatcca
    11401 tagctgaatt agcactttcg acacgtacat tcactttaag agatgggaat gaatttttta
    11461 gtcgacttaa aattggtgga agtaaaaaag aggcaattgt aatgctagaa acaatgttta
    11521 taggtgtaca ttcctctaaa tgactgattc ttttgtctaa attacgacaa gcagttaaga
    11581 tactacgtgc ttcttctaaa agagaaatgc cacagcgagt aagacatacc cctcgtggta
    11641 gtctgtcaaa taatgctgtt tcagcttgtt gttcaagttc agctatagca tgagatacag
    11701 cagattgtgt gatatgtaat ttttttgcag cacctgtaaa agtgcctgtt tgttcaattg
    11761 cttctaaaat ctctaaatat cgtatgttta tcataataaa tatcctcact agacatgaat
    11821 aaaattgatt aattccatta aattctatca ttttacagat tgcaaagcaa caggtatact
    11881 gaataatatg aagtgaaaag aaggaggaat attttgaatc aaagcagaaa aacatatttt
    11941 tggcttttaa ttattaactt gtttattagc acattcactt ttggtggagg gtatgtagtt
    12001 gtacctatga ttagacgtta ttttgtaaat caaaagcaat tctttacaga agatgatttg
    12061 atgagcatgg cagcagttgc acaatcaact cctggagcta ttgcaattaa tttatctgct
    12121 ttggcaggtt atcgagtagc tggtacttta ggggttgtca ttagttgtat agcagctata
    12181 atacctccgc tcgttattct tggattagta tcagcatttt acaccacttt tatatctaat
    12241 gccattgtaa ttgcagtatt aaaaggaatg caagctggtg ttgctgcact aattgtggat
    12301 ttgattattg acatgtgctc tatgatatta aaacaacgtt ctctattttt atcagctatg
    12361 atacctattg ctttctttgc aaactttgtg atgagtataa atgtaatttt tatattatct
    12421 gtttgctgtt ttgtatgtgt aatgcaagtt ttctacaaga agagggaaaa taaatgaata
    12481 caatttggaa tttatttttt atatttttaa aaataggctt gtttagtatt ggtggtggtt
    12541 atgcaatcat acctttaatc caagagaaag tagtaaatca aactggatgg ataagtgaga
    12601 aaatgtttac agatattata actatttcac aaatgacacc agggccactg gctgttaata
    12661 cttctacttt tgttggactt caaattggag ggttttgggg agcagttgca gccactttag
    12721 gttgtgtatt atgtggtgta gtaatatctc tatttttata taattttttt caaaagcatc
    12781 agaactctac ttatatattt gaaatattaa atggtctaaa atcagcttca ttaggtttaa
    12841 ttatctcagc tgcggctaca attataatcc ttgcattatt tgggacgaat aaagtgtact
    12901 tcaattctat atttgagatg ctaaactgga ctgcactaat aatctttttt gttacactac
    12961 tgatagtacg taagtggaaa attaatccta ttgtgattat aataataagt ggtatactgg
    13021 gaatattttt ttatttataa gtttttgcta agtaaaggat atctattttt ttatatctta
    13081 aatccaaata gccaataaag taaggctatt tggattttta ataaattctg aaaagataat
    13141 cagaaaccca tataacattt aaattatatc actggttttc tacaaaccaa tcataagctt
    13201 cttggcaaaa tttctcacta tctatatagt aactattatg aacattatta atttcaacaa
    13261 gtttcttttt acattttagt gaattataat agctatcaaa atattgggtt ttaaaatatc
    13321 tatcatgaag tgttttaaag acaagagtag gtatgttgac tccatctttt atcttactat
    13381 cttctgcaat aaagcattct aacattgtat taattatctt tgtactattt ttccaaatat
    13441 gaggattttt cttttcaaat attttataaa attcattatc atagacttca ttataacctt
    13501 tatatttagg tggttttact gttatgtgaa aattaggaag aaacttaaag aaaaaatata
    13561 ataattttta tgttctgttt tatatattat tcatatttta tcacagataa tatactaaag
    13621 ttaatttttt tattgtacaa ctattataat aattcttcta taatataaga cattctataa
    13681 ttttatattt aagttcatgt gtatttaatt gtttttatat aaaatgtcca gtaatactat
    13741 ttggatttat ttttatttca tcaggagttc cagaagcaac aatttcccct ccatttattc
    13801 cactgtctgg acctatatcg ataatccaat cagaagcacg tataacctct gtattgtgtt
    13861 caataattaa aagtgaatgc tgttcattta caagttttct aaaagtaatt aacaaatttt
    13921 ctatatcttt aaaatgaagt ccagtagtag gctcatccaa tatgtacagc attcgttttt
    13981 tagtttttgt ccctaattct tttgctaatt ttatcctttg agattctcct ccacttaatc
    14041 ctaatgtatt ttgtccaagc tttagatatc caagtcccac ttcatctaat aaggagagtt
    14101 ttctatatat atcagagcaa tcgctaaaaa atgtttttgc ttctgctact tccatgtcaa
    14161 gtatatctgc aattgtcttt cccttgtatt gtatagacag tatttctttt tgatatctct
    14221 taccttgaca tttactacaa gttacccatt ggtctgccat atattgcaga ataatttttg
    14281 ttttacctaa tccttgacag tttgggcatt gccccttttt gctattaaag ctaaaatagc
    14341 tttcatccaa taatttttgt tttgcttgtg gagtttcagc aaatagagaa cgaatttcat
    14401 caaaaatatt gatatatgta gcaggtgtag aacggctaga ttttccaata ggtgtttggt
    14461 ccattaagat aaaatcatca atagcatcaa atccagtaaa ttcagtataa tttttatctg
    14521 ggatagattt ttgtttcaat ttttcttcta gagcaggaag taaactgtga aatacaagag
    14581 agctcttacc agaaccacta acacctgtaa tagagcacat acagtttaag ggaatttcta
    14641 catcaatatt ttttaagtta tttgcatggc atccttttaa gcttaaccat ttacttggga
    14701 taattttatt ttgtgaacct gttttattgt atgtacttaa atatttacct gttatagagt
    14761 ttggattttt tataatttct tgggttgtac cttctgcaat aatgaacccc ccttttgtac
    14821 cagcacttgg gcctacatca ataatataat cagcagacag tattgtatct ttatcgtgtt
    14881 ccacaactat aacagtatta cccttatctc ttagctcttc tatcattttg atgattaaat
    14941 tatggtctct tgggtgtaaa ccaatagatg gttcatctaa aatgtaggtt aagcctacta
    15001 attcacttcc tagctgactt gataatcgta ctctctgcag ttctcctcca gataaagttg
    15061 gagctgttct atctgttgat atatagctaa gacctacctt taatagataa ctaactcgaa
    15121 tttttaattc tgttaagata tcatttacca aagagagctc atttttttga agttgatttg
    15181 gtaattcaca caaccaattc cataactgtt ctatcgtcat ttttgttagt tcagggaagc
    15241 gataaccttt gattgtagtg aatctagcct caatgcacag caattcgcca ccacatgtat
    15301 tgcaaggaat tttgttcata tattgatgca aggtattatt ttcagaacta gattctctaa
    15361 aaagtctttg aatgtggttg attgctcctg aagcaggtct tctaatcttt gattctcgtc
    15421 cctttgattc aaagctaaat tcatatatct tatcgtctgt accatataag attgcatcta
    15481 taaaatctct tggtaattca ttccaaggta tatctaggtc tatattttta tcttttgcta
    15541 ttgcatataa ttcacctacc atccaattac catttggctt tttccccctc aattttccaa
    15601 aatagtaagt ggctccatct aatattgaaa tagttgggtc ttttacaatc aattgaggat
    15661 taacttgata ggtaaaacct aatccattac aatcgtgaca agctccagta tgggagttag
    15721 cattgaaggt tgaagtattt atcttagaaa aaatagtttg acaatgtgga caataatttt
    15781 ttgtattatt ctttttttct aatggaattt tgcaatatgg acagtaactt tttccgattg
    15841 atacaaataa cattcttaaa taatcccaaa tgcttgtaag agtaccaaca gtagagcgag
    15901 gattttggct tccttttttc tgttcgatag ctatagtagg ggttaatccc tgaagtaaat
    15961 caaattccgg tttttgaagc tgttctgaaa gttttgctcc attacttaga ttttcaaaat
    16021 aacgtctttt tccttcttca taaatcgtat cgaaagctaa agaagatttt ccactaccac
    16081 ttacacctgt aataacagtt atttgatttt ttggaattgt aacctcaaca tcctttaaat
    16141 tgttttgcct tcctcctttt aaatagatag agcttttatt atgacaaagt gaatttttaa
    16201 ttgatttatt tattgatttt gtaaatttga atttcttttc gagttcaaga ggattgccta
    16261 attcttttat ttccgaaatg cctaatattt ttaactgaga aaagattgat ttcaaataat
    16321 cttcaggcag tttttctatt aacaaattaa ggtcttctat ttttatattt ccgattgata
    16381 atatttctgc catttcatct aataaatttt tttctgctct tgttaattga ttgtattttt
    16441 tggaacttaa ttctgtccat aaatcccatg gaagcaattc taaaccaatc atattattaa
    16501 agtcatgtag aagattaccc tttacagaat gccaaccttt ccaattttta ttatatccaa
    16561 agtcatctgg atgagcatgt ccttgccgac atcttatcca ggcttctgaa ccagttaaaa
    16621 aaccatctgt ttttccgaca tcatgagtgt caaaattaat ttgaaaataa tttttttgta
    16681 tgtcatctat ttgtgcatct attcttatcc atctctttgt tagagtatca tagtattcta
    16741 caagccagtg gtcttcataa gtaagctcac tttcaaaata attagcaaaa cctgctctca
    16801 ttctagcctc aaaacctcga tatcttagga gcgatacaag aagtaaagaa taatctctgc
    16861 acattccaac aagcctttgt tttgggtttc ttggaatagt tagtgggtta gaatttattt
    16921 caaatattct ttttaacatt tgaggaattg tacgaagcaa ttcctcatca gattgttgtt
    16981 tattaaagga tataccatat aattttcctt ggtctccatg aattactagg ctttgaacca
    17041 cttttaataa ctcaattgga gtctttggta aatcttgata tttattttca aattttttag
    17101 gatttgtgat gatactttga tttttatagt tatttatttt catttatatt tcacctctct
    17161 aaatggatga tataccctga catggtgtca tatgcaagga caatttagat tttttggcca
    17221 aaatttaaaa ataaataaaa aatgatacag tgataaattg taatacaaat atagtttcaa
    17281 attgcatata atataattat ttaataaaac cattatctat tgaatgttaa tgaaatgtta
    17341 agatggcatt cttgaatatt aagaaataga atactataat atagtgtgaa ggatttttag
    17401 taaaaaaatt tgtaagtgtt aatatacatt aaaaaatagg tttataattt ggaggaaaaa
    17461 aatgaaatta tcaaggtata agaaaaatag tttagttctg tctataattt tatgttcact
    17521 tattatttca atccttgtaa ttactgtttt taataccgta aaactacaca atatatctaa
    17581 taaacaatct aaaaactatt taaatgatgt atctacacag attgtaatga atgttgattc
    17641 taaaatcaaa tttattttat ccgacttaag aataatggca gattttatta agcaatatga
    17701 aggtgatagt cgatatgagt atttatctaa aagaaagact agttataagt attatgatgt
    17761 tggaataata gatttagaag gtaaagctga gtttttaagt ggaaaaaagt ttgacttaaa
    17821 gaatactgtt tcctataaaa aaggaattga aggtaaagaa tactcagaag taatagagtc
    17881 aatgggtttt gttctttata gtgtacctat atttaatgat aatcatgaag tatctagtat
    17941 tttaataggt gtatccaata aagaaagtat gaatgagatt cttaatatag ataactttaa
    18001 tggaaaagga actattgaaa ttattaatag taagggaaaa cctcttttca taggaaaaaa
    18061 tactgaatta ataaaggacc ttagccataa atataagagt tctggagatg aaccttgggc
    18121 acaaaagatg cttgaggatt ttaaaaatga taaatcaggg aatattacaa taacctcatc
    18181 aaaaggtgta caatgcttat taacttatca tccaattaca agaggtttaa atgattggca
    18241 ttttcttctc atagtacctg aagatgctgt acttggtgaa cttaataaat taaactcttt
    18301 tacaataaca atgacattta taattacatg tattattgga attataacat taattttata
    18361 tattataaga agaaaatatg taaatcaaat agaaaatatt gcatatttag atagtataac
    18421 aaatggtata aattcaacta agtttagtat gctagtcaaa cctttaattt cagaatcacc
    18481 tgatagtact tatatgatga tagcaatgaa tataaaagat tttaagctaa taaatgattg
    18541 tttcggtagt gaaaagggaa atatgacact aaaacatctt tacaatattt tgtataaaaa
    18601 cattgatgaa aatgaagagt ttgtgtgccg tcatgatgca gaccttttct atttgcttat
    18661 taagaataga ccagtgttag aagccctgga gttattatat aaaatagaag ctgacacaaa
    18721 ttattttaat aaaaataggg aaaatccata ctttttaaga ctatcagtag gtatttacac
    18781 aattgaaaat cataatgaag atttaattac aatacaagac catgcaaata cagcaagaaa
    18841 aagctttaat aaaactcatc aaagtgattt ttctttttat agtgatatag aaagaaaacg
    18901 attaatatct gaaaaggaaa tttcaaattt aatggaaaaa gcccttgaaa ataaagaatt
    18961 ttttatgtgc ttacaaccta aaattgatat aaaaagtgga aaaattagtg gagcagagtc
    19021 tcttgtgcgt tggaaaaatt cagaaaaggg cataatttat ccaagtgatt ttattcctct
    19081 tttcgaaaaa agtggattta tatgtaagtt agatttatat atactagaag aaacatgcaa
    19141 attgatttct aagtggataa aagaaggtaa agaagtgttg agaatttctg ttaatgtatc
    19201 acgtcaacat ctgaatgata aattgttttt agaaaaatat aagcatatat gcaataaata
    19261 caatgtacca acatgtctga tagatttaga acttactgaa tctattttct tagaaaatct
    19321 agaagctata gatataatag aggatattca ttctaatgga tttaaatgtt ctatagacga
    19381 ttttggattt gggtactcat cattagggat attaaaggat tttaaagttg atataattaa
    19441 gttagaccgt tcattctttg ttagcaaaaa taatatagac cgtggtaagg tagttattaa
    19501 gtctattatt gaacttagca aaaggctagg tatgaaagta actgctgaag gaattgaaga
    19561 attagaacaa gttgagttcc taaaaaatgt gggatgtgat tatattcaag gttatgtttt
    19621 ttcaaaacca ttattaattt ctgactttga aaattttgca tatgaaaata ataaaattaa
    19681 aaatatccat tattaaatgt acaagataaa aaatttaggc aagttatata attaaaaata
    19741 taacttgcct tttttattta tatatttaat aaaaatatat ttgcagattt tgtaaaaata
    19801 attttcaaat gttgtaagtt gtggctaaag ctttattgta ttattctgaa tatagaaaga
    19861 tagttactgt cttagataaa aactgaaaca tacataataa tataaaattt gctatattaa
    19921 taactctaat tattttggaa ggagggaaaa tatgataagt gggagaatgt tactcatcat
    19981 gaattttcta aaaggaaaaa ataagacaag ttacaaggat attagcaaac aacttagtat
    20041 agaagaaaga aaagttagat atgatataaa taatttaaat attgttttgc gttcattaaa
    20101 caagtcagta atacaaaaga tgaacaaagg tgtgttaatt attcctgatg acttccaagt
    20161 agtatgtata aataataacg aatatgtatt ttccttaact gagcgagtat ctattatgaa
    20221 aattatatca atgtttaaaa tagataatct aaacttagaa aaattaagta aagaatttca
    20281 ggtttctaga agttcaatta aaaatgacct taatgttttg tcaagtgaat tagaaagaaa
    20341 ccaaataact attacttatg ataaatcttt taaaataagt ggagaagaag acattatata
    20401 taagcaaaga ttgaacatat taaaatcgta ttcttatctt tttggtaagg aaaaatctga
    20461 tttaagtgta tttgagaagt atttagtgaa tgtaattgaa aaaatattca aagggattta
    20521 tttgattgat atatataatt ggtctatgaa tttattattg caaatgggat ggactttaaa
    20581 tgatgaatct tttacatggt atgtgtcgaa cattttcctt tttacatggt atatacattc
    20641 agatgaaaaa catcctttag aatctgcttc attaagtgag ccgtgttttg aaaataagtt
    20701 tgaccaagaa tttgaaacaa ttattcaaaa aaagttgact aaggaacaaa tttttctgtt
    20761 aaagagtttt gtatttttta caaataaata tgcaagttta aacgaggata tggatttgat
    20821 tagtacagaa attatagttc aagacctaat ttacaatatg tcagaaatat tagagattag
    20881 ctttaaagaa gatatgattc tttataaagg attactcaat catattgctc cattgataga
    20941 gagaatcaag cagaatatac agatttatga ggaattactt catgtaatac cagataaata
    21001 tcaatatgta cttgaagcta ctaaggtttc tattcaaaaa aacagagttt taagtcaaat
    21061 aaagaatgaa aatgaaacaa tacttttggc aatacatttt ttaggaagta tacatagaaa
    21121 tgagaggaat aactacaaaa atatattgtt agtttgtgga tttggatatg gtgtaattgc
    21181 tatgttaaag gatagtttag taaatgatta ccagataaat atagtagaga gtattccatc
    21241 atataagtta caagattata aagaatggga aagtattgac ttcattataa caacatcaaa
    21301 gatagtaata gacttgccta aaacaattat tgagataaat ccatttttac aagaagagga
    21361 ttatttgaag tttgaagaaa aagggataaa aagaaagaac gtcttaacta attatatgtc
    21421 aataaaaaaa aggttggact ttttagaaga agatgcccaa aaaagagtat taagtattat
    21481 atgtcaagaa cttggataca gtgatgagag aatattattt agacaactta atttaagtga
    21541 tttaataggg attgatacca taaggataat tgatggagat atgaaatggg aagatgctgt
    21601 aaaatttagt tcaaacatac ttgctaattg tgattttgta tcagcacaat atgctgagaa
    21661 tattatagat attttaaaaa atgtgggttt ttatgctgta aaagataacg aatttgcttt
    21721 actacatggc aatgatagtt cattagtcaa agtaagttcg ataagtttat taatatgtaa
    21781 agaagcagtt agttttggag ataaaaaggt taaaatcata ttttgcctag caagcagaga
    21841 taaaaaagag caaattcctg caataattaa tctaactaaa atggtttata agactaattt
    21901 tattgctatg ttagaaagtg caaagacaaa agaagaagca gaagttttaa ttcataaata
    21961 tgagaaggag gtcactgtat gaataaatta gttaatgtaa aatgttcatt taaaatacat
    22021 gttaattcaa aagaagaagc cattatatcg ttagttgatg tagtgtcaaa agaaggatat
    22081 ttaatagata aaaatcaatt tttaaaagat gttttaaaga gagaagaaac attgtcgact
    22141 tatattggac atggtatagg tcttcctcat agtcaaagtg taggtgttaa aaactcttgt
    22201 attacaatag gaaagcttga tactcctatt gaatggacag aagaaggaga aaaagtggat
    22261 ttaatatttt tgatatcagt aacaaaagac aatgaaaata atcttcattt aaagatttta
    22321 tcaaaattag cacgtttatt gatgcatgaa agttttagaa atcaaattag atgttcagat
    22381 gaacaaactg tttataatct tataaaagaa aaaatagagg aggaagatta aaatgagaat
    22441 tttaaagttt ttgcaaaaac atcttatgac agcaacatct tatatgattc catttgtggt
    22501 tgcaggagga atattatttg ctttatcagt aactttaagt ggacaagctg ctgttcctga
    22561 aacaggctgg ttggctaaac tgaatcaaat tggagctgct ggcttggctt tattcattcc
    22621 tatattaggt ggatatatag catttagtat ggcagataaa ccaggattag ctccaggtat
    22681 gataggtgca tatttagcaa aagaagtaaa tgcaggtttt ataggtggta tcatagcagg
    22741 atttatagca ggatttgttg ttttacaatt aaagaaaatt aaattagctc ctacaatgag
    22801 aactttaggt tctatattta tttatccttt agttggtaca ttgattacag gtggtataat
    22861 tgtattttta attggagaac ctatagcttc ttttatgaca tggatgacaa actggttaaa
    22921 tggaatgtct ggtgtttcta aaattccttt aggtggaatc ttaggaggaa tgatagcctc
    22981 agatatgggt ggccctataa ataaggttgc tgctactttt gcccaaactc aagttgacac
    23041 acttccatat ttaatgggtg gagttggcgt tgcaatttgt atacctccaa ttggtttagg
    23101 attagctaca ttattgtttc caaaaaaatt tagcaaggaa gaaagagatt caggtaaagc
    23161 ttcactatta atgggatgtg ttggaattac agaaggagct attccatttg caacatcaga
    23221 tccagttaga gtaatacctt gtattatggc tgggtcgatt gtaggaaata ttatggcttt
    23281 tttattagga tgtttaaatc atgcaccctg gggaggtctg atagtgttac ctgtagttga
    23341 caataggttg gggtatattg catcagtatt aactggagca gtagttgttg cggtattaat
    23401 gaaattagta aaaaaagacg tgaaagaaga tgaagaaatt gaagaagatt tagatgaatc
    23461 aattgaatta atatttgaag aattataaat ataaatggaa ggaatttgta taaaaaagta
    23521 aatataaaac tataaattta aaggagataa gaatatgaaa attgtagcag taacatcttg
    23581 tcctagtgga gtagcacata cttacatgtc ggctgaatca cttgaattat cagccaaaaa
    23641 atttggtata gaaataaagg ttgagactca aggaagctct ggaatagata atgaattgtc
    23701 acttaaagat attgatgaag caacttgtgt aatattgact aatgatgttg agattagaaa
    23761 tatggaacgt tttaaaggaa agaaggtagt aagaatgagt gtatctgaga taattaagaa
    23821 atctgatgca ttaattaaga aaataaaaga tacttttcaa taaaaattga tttattttac
    23881 atataactca aagatgtttt taaagaaatt tttattaaaa gcatctttga aaatatctta
    23941 aaaatagaat aaaaggagat atagtcatga aaaagttacc aataaagact gtcgtgcaaa
    24001 gattactaaa cttacaagaa gaggggaaaa gtgcaactct tttaggaatt ggtcctatgt
    24061 caccaaactt gttacaagca agttttgaac tagcaaaaga tgatgatttt cctttaatgt
    24121 ttatcgcaag tagaaatcaa gtagatgcag atgaactagg tggcggttat gtaaatggtt
    24181 ggaatcagga aacttttaca aaagatatta agaaggttgc cgacaaagtt ggatttgatg
    24241 gtttatatta tttatgtaga gaccatggtg ggccatggca aagagataaa gagagaaatg
    24301 accatttgcc tgttgatgaa gcaatggagt taggaaaaaa atcttattta gcggacattg
    24361 aagcaggttt tgacctattg atgattgacc ctacaaaaga cccatttgaa attggaaaag
    24421 taattccact agatgtagta ctagaaagaa ctgtagaatt aattgagtat tgtgaaaacg
    24481 agagaaaaag acttaatcta ccagacatag gttatgaggt tggtacagag gaaaccaatg
    24541 gaggtctgac ttcaactgag acgtatgaaa catttataac tagactaaag gttgaactcg
    24601 ataatagagg tttgccaatg ccaacattta tagttggtca aactggtact ttaactagaa
    24661 agacagaaca agtaggaact tttaatttta gaaatgctta tgatttagct caaatggcta
    24721 agaaatatgg agttggttta aaagagcata atggcgatta cttagatgat gtaactttat
    24781 tagaacatat accatctcaa attattgcta caaatgtagc tcctcaatat ggtactgaag
    24841 aaactagggc atatttaaaa ttagcagaag ttgagtgtaa attagaaaaa gagggtttag
    24901 ttgagaaaac ttctaatatc agacatgttc ttcttgttaa tgcaattgaa tgtggacgtt
    24961 ggagaaaatg ggtagtagga gaacaaaaaa atctaactac tgaagagata tttaaggatg
    25021 aagttttatc taatgaaata ctagatattg caggacatta tacatttaat aatgatgatg
    25081 ttaaaaaaga aatagaagtg ctttatgata atttaagtaa gaataatatt gatggtcaaa
    25141 gatttgttgt agaccatatt aaacgtcctt tgcgtgatta tgcagaatgc tataacttaa
    25201 aaggtgttac tacgaggatt ttaaataaat aataggactt atagtggtga gtattgttat
    25261 actaggtatt tatagttata attatactta ccactattaa atttaggagg actaatattt
    25321 tgattaattt aatttttgat gtagatgata ctttatataa tcaattaacg cctttttaca
    25381 ctgcatataa taaagtgttt tcttcaataa aggatatttc tattgaagat ttatatatga
    25441 gtagtagaaa gtatagtgat gaggtatttc atatgactga aaatggagaa atgccaatca
    25501 aagaaatgca tatttatagg ataatgaaag cttttgagga gttgggaaat tctattacag
    25561 aaaaagatgc acaaagtttt caagatgagt atatatatca acaatcacaa attacactaa
    25621 taccagaagt tgagaggatt ttaaattttt ctaaagaaag aaatattaat ctaggaatta
    25681 taactaatgg cccatcaaac catcaaagaa tgaagttaaa gcagttaaat attgaaaact
    25741 gggttgataa aagtaatatt tttatttcta gtgaggttgg attttctaag ccagatacta
    25801 atatttttag agtagctgag aatgttatga atttagatag agaaaataca tattatgtgg
    25861 gtgattctta tagaaatgat gtattaggtg ctaaaaaagc tggttggaag agtatatggt
    25921 tgaaccatag aggacatgag gtagaagagt tgttttataa acctgatttt gtaattttgg
    25981 aacataagga tttgatatct ttatttataa aaatatgtag ttataaaaat atgtagtaaa
    26041 aaaatgttaa taatagaatt gtataaaata attaataata actatataaa attatatgtt
    26101 tagattgtga gcaatctatt ttatgttaaa aatagattat ttagaagaag gggaaatctt
    26161 aaaaaaattt gaatatcccc tttttattat ttaattaaaa tgaaatagtt agaaatatat
    26221 tttatttagt ttagtcaata acattttggg attctttata actacatgtt aactgttgaa
    26281 taggtttatc atatggttta acccatcctt tattaatact taattctgta agtgctgtgt
    26341 gaccttctac catttgagtt aatgaagctg aatatatagc tcttaattca ggtgtactac
    26401 ttgtcaatgc agaattaaga tacatattgg cagatgcttt agcagatgaa agcatactta
    26461 acattattac tttatcgtct atataagtat tgttcttaat tagattttct atcatatttc
    26521 tcatgttatc tatacctcct cagaaattag tatttcattt tcaactataa attgttgtat
    26581 agctttaatt cttcattctg ttgctaatat actagattct gattgtcttt ttaggtcttc
    26641 atctgatatt aacatattta ttgctctttg cataagtaat ccgtcagact ccatttttat
    26701 aattgctgct aaagatattt tttcagtttc tgaaagtatt ctcatttaat catctcctat
    26761 attgtaattt atgctttaat agtatgtctt tcttttcaag gaaataacca ttacactttt
    26821 ttacagtatt ttatattctc tttatatcaa aatttagtcg acctaattaa tataattttg
    26881 taggatattt atcattaaat atctataaaa taaattattt gaatattcat aaagcaaaat
    26941 ttatttgtat gtacttcttc aagagtcaat atgagttttt tcaaaaaatt aatttttatg
    27001 ataatcatta agggctatat ttttcttaaa gttgtgatta tcattattaa tttaccttag
    27061 aggttaatta ggtgtttaat caaagttaat gcctttagaa tacaaatgta ttctaaaggc
    27121 atttttacta tgtattttca tttatattac taaacattat ctatttttat atacatttct
    27181 atgtatttta ttttcatcaa atcggtctat aaactcattt ttttcttcac tatatccaat
    27241 agatataagt gcataaggaa ctaattttaa tggtaagtct aaagtttgtc taactttatt
    27301 taccacttta tttttaggaa atactcctgc ccaacaagca gctagacctt gattagtaac
    27361 ttctaataat aaattttgtg tgcaagcacc taaatcttgt atccatttac caggttttaa
    27421 gaatttatct ctatttccaa gcactactat acataatggt gcaaattcta tatgctttgc
    27481 tctatgctgt gactttgaga gctgtttcag cagttcctta tcatctacta taataaattc
    27541 ccaaggttga gcattttttg atgaaggtgc ttgcatagct gattttagta tttcagttat
    27601 tttatcttct tctatatttt tatctatata tgttcttatt gaacgtctat tttttataac
    27661 ttctaacata cagattctcc tttaaataaa attatttcta tttatataat atcattactt
    27721 taaattttag ctattactta tataaagaat aaactttgtg ttggttttat ctaagtaaaa
    27781 gtaacattca gaactaaaaa acaagactat aaatccaaag tattaattaa aaaagaagta
    27841 ataaaaaata atatacaaga tttaaaaaag agtattgggc ttaaaattta attagaaaac
    27901 caattttgag ataatctgtt ttttatttta acaaaaaaac ataaataaag ttcgatacgt
    27961 agcgaatgaa aaaattacaa gaaatatttt ttttaaaaaa tttcaaaaaa gagttgataa
    28021 tatatgtata ttaatataaa atttaaggtg tataattcgt ataataatac gaatgatttg
    28081 tagtgtaaaa taacttataa acggagaggg gaagtctaat gaaagtagca gtagttatgg
    28141 gttcaaaatc agattatcca aaattagaag aagggataaa actgcttgaa aaatatggaa
    28201 tagaagttgt agcaagagca ttatcagctc atagaacacc agaacaactt tcaatattcc
    28261 taaaagaaat agaagatgat actgatgtaa taatagcagc agcaggaaaa gcagcacact
    28321 taccaggtgt aatagcttca caaacattaa ttcctgtaat aggattacct attaaatcat
    28381 caactatgga tggactagac tcacttttat caatagttca aatgccaaaa ggaatcccag
    28441 ttgcaacagt tacaatagac ttaggtttaa acgcagcttt attggcatta caaataatga
    28501 ctttaaaata cccaaaatta aaagaggatt tgaaatcata tagagaagag atggcacaaa
    28561 aggtgttaga agacgacaag aatttaaggg ggtagcagaa atgttattat atgaaggaaa
    28621 agcaaaacaa gtatattcta cagataatga aaatgaatat gttgtttatt ataaagatga
    28681 tgcaacagca tttaatggag aaaaaaaagc agaaatatct tcaaaaggta tactaaataa
    28741 taagatatca acaataatct ttgaaatgtt aaaagaaaat aatataaata ctcactttat
    28801 aaaaagttta tcagatagag aaatgttagt taaaaaagta gagattttac cattagaagt
    28861 aatagtaaga aatattgctg ctggttctat ctgtaaaaga gttggtcttg aagaaggtgt
    28921 agttttcgat gagccaattt ttgaaataag ctacaaaaat gatgcttatg gggacccaat
    28981 gctaaatgat gattatgcag tggcaatgaa gttagcaact agagaagagt taaaattctt
    29041 aagagaagaa actttaaaaa taaatgagtt actaaaagca tttttcttaa aattaaacct
    29101 aaagttagtt gactttaaaa tagaatttgg taaggattct gaaggaaata taatattggc
    29161 agatgaagta tcaccagaca cttgtagact ttgggatgta aatacaaatg aaaagttaga
    29221 taaggacaga tttagaaaag accttggaga ccttgtagaa ggttatacag aagtactttc
    29281 aagaatgaat aataaatagg aggcaaatgt atgtgtggag ttttagggat ttactctaat
    29341 aaagatgtaa ctaaagaact atattattct ttatattcta tgcaacacag ggggcaagaa
    29401 agctgtggtt tagctctttt agatgatgga gaaattaagt acaaaaaaga tatgggatta
    29461 gttggagatg tttttaagga aaatgaatta tctaagttaa aaggaaatat agggattgga
    29521 catgttagat attcaacagc tggaggaagt catgtttcta attgtcaacc tttagttgga
    29581 agttgtagaa aaagacaatt agccatagct cataatggaa atctagttaa tgcaaattat
    29641 ttaaaagata tgctagaaga agatggatat atgttccaaa ctaattcaga tacagaagtg
    29701 attttatata tacttgctag atattacaaa ggggatatag tagaaagttt aaaagtgaca
    29761 atggattata taaaaggtgc atatgctctt gtaataatga gtcaagaaga attggttgca
    29821 gttagagacc cacatggatt cagacctctt gtacttggta aaaagggtga tgaatatata
    29881 tttgcatcag aaaattgtgc aatagatata cttggcggag aagttataag agatgtagag
    29941 ccaggagaga taatagtagt caaagatgga gaactaaaat catattttta ttcagaaaat
    30001 tataaaccag ttaagaaaag ttgtatattt gaacacatat actttgcaag aaatgatgca
    30061 actatagaca atgtaaatgc atatgaattt agaattaaat gtggtgagag attagctcag
    30121 aatgaaactg taaaggcaga tatggtagtt ccagttccag attcaggttg gccaggagct
    30181 attggttatg caaatgctag tggattaaaa ataagtgaag gcttagttaa aaatagatat
    30241 gtaggaagaa catttataaa acctacacaa gaagaaagag aaatagcagt aaaaataaaa
    30301 ttaaatcctc tttcaacaat aataaaagga aaatctataa ttttagtaga cgactcaatt
    30361 gtaagaggaa ctacatctaa acaattagta aaatctttaa gagaagcagg agcaaaagaa
    30421 attcatctta gaataacttc tcctccagta gcttactctt gttactatgg aatagatact
    30481 ccaaatcgct ctaaattaat tgcatcaagt aacaacgtag aagaaatgag agaatatatt
    30541 ggatgtgata gtttaaaatt cctagatata gaaggaatgt tagatgcaac agaacataag
    30601 tctactttct gtaaagcttg ttttgatgga gaatacccag ttaagaaaat tgataaggag
    30661 gaactacttt catgttaaca tataaagaat caggtgtaga tatagatgaa ggaaatagag
    30721 cagtagacct tataaaaggt aaaataaaag gaacttatga tggaaatgta gttggagatt
    30781 taggtaactt cagtggatta tacagtttaa aagattttgt aggtatgaaa gaaccagttt
    30841 tgcttgcatc tacagatggt gttgggacta agttaaaaat agctcagatg atggacaagc
    30901 atgatactgt tggaatagat ttagttgcaa tgtgcgtgaa tgatttaatt tgtcaaggag
    30961 caaaaccatt attcttcctt gactatatag ctcttgggaa attagtgcct gagcatatag
    31021 aaaaaatagt tggtggaatt gcagatggtt gcaaaatgtc tggttgtgca ctaattggtg
    31081 gagaaactgc tgaaatgcct ggaatgtatg gagaagatga ctatgattta gcaggatttt
    31141 ctgtgggaat agcagacaaa gaaaagattg tttctggaaa caatgttaaa tcaggagatg
    31201 tattggttgg tatatcttca agtggagtac acagcaatgg attttctttt ataagaaaga
    31261 tatttttaga aacttacaat tataaaatgg aacaatatgt tgaagaacta ggaatgacag
    31321 ttggagaagc acttttaaca ccaactaaaa tatatgttaa attagcttta gatgtattag
    31381 ctaaacatga cataaaagct atagctcaca taactggtgg agggcttata gaaaatataa
    31441 caagagttat acctaaaggg ttaggactag atatcaataa aaaatcttgg gagaagcctc
    31501 ctatatttaa aatgatagaa ggttttaatg ctgttgatga gagagaactt cataagagtt
    31561 ttaacatggg tattgggcta gttttaatag tagataaaga aaatgctgat gatgttgtaa
    31621 actttataaa taatagagaa aatgacaatg ctgattatgt agataaaaaa tatagtgaat
    31681 tattagaaga taaagcttat ataattggtg aagtagtaga tagtcatgaa ggtgtagaat
    31741 tatgctaaat ataggagttt taatatctgg tgggggaaca aatttacaag cagttataga
    31801 tggtactgag tctggagaaa taaaaggtca ggttaaagta gttatctcaa gtaagcaagg
    31861 tgcttatggg ctagagagag ctaaaaatca taacataaaa gcaatttgtg aaactgatga
    31921 agacaagata atagaaattc ttaaggaaaa taaaatagat ttagtagttt tggctggtta
    31981 tttaaaaata atcagcccaa agctggttaa tgagtttaga aacaaaatga taaacataca
    32041 tccatcatta attccttcat tttgtggagc tggattctat ggagaaaaag ttcatcaagg
    32101 tgttatagat tacggagcta aagtaactgg tgctacagtt cattttgttg atgaaggtgc
    32161 tgatactgga ccaatcataa tgcaagatgt agttaaggta aatcaagatg atgatgcaaa
    32221 gacacttgca aaaagagtgt tagaagttga acataggatt ttaaaagaaa gtataagtct
    32281 tttttgtgaa aataaaataa aacttcaagg taggagagtg tttataaatg agtaagagag
    32341 ctttaataag tgtaactgac aagactggtg tagtggaatt tgctaaagag ttaaataaat
    32401 tagattatga aattatatct acaggaaata catttaaaac attaaaagaa aatggtgtta
    32461 atgtaatgca agttgaagat gttacaaatt ttccagaaat attagatgga agagtaaaaa
    32521 cattaaatcc atatatacat ggtggtatac tttataaaag agataaagaa tctcatgtag
    32581 aaactgtaaa tgaacacaaa atacattcaa tagatttagt agctgtaaat ctatatgatt
    32641 ttgaaggaac tttaaaagct ggaaaaagtc atgatgaaat aattgaaaat atagatattg
    32701 gtggaccatc tatgatacgt tctgctgcca aaaactataa ggatgtaata gtagtagtag
    32761 atataaaaga ttatgattct ataatagaaa aattaaaaac agatacaatg acattagaag
    32821 acagaaaaaa attatcatat aaagctttct caactacagg aagatatgat gcgttaatat
    32881 ctagttattt tgctggagaa gttggagata cgtatcctga catattaaat ttaactttcc
    32941 aaaaagaaca aactttaaga tatggagaaa atccacatca aaatggtttc ttatattcac
    33001 agtcaaatgc aaaaaatcca atcttaaatt atgagcaatt aggcggtaaa gaactttctt
    33061 ttaacaactt aaatgattta catggatgtt tagaagtaat gagagaattt aaagatagtg
    33121 aagaagtagt ttcagtagct ataaaacatg ctaattcatg tggggtaggg ttaggaaaag
    33181 atgcttttga agcatataca aaatgttatg aagcggataa ggtttcaata tttggaggaa
    33241 tagtaggaat aacttctact atagataaag ctacagcaga gaaattaaat gaaatattct
    33301 tagaaatagt agtagcatat gattttgaac cagaagcttt agagatactt aaacaaaaga
    33361 aaaatctaag aatattaaaa ttagctaaaa tagaaaatag tttacaacca tatgaaatga
    33421 aatatttaga tggaaaatta ttgatacaag atagaaacaa tatattagca gaaaaaagtg
    33481 aaaatgtaac aaaggaaaaa ccaacagatg cacaacttaa ggacatggaa tttggtatga
    33541 gagtagtaaa aaatatgaaa tcaaatgcaa ttgcaatagt aaaaaatgga caaactctag
    33601 ctttaggttg tggacaaaca tcaagaattt gggcattaaa aaatgctctt gaaaataaca
    33661 aagataaaga ttttacagga gctgttttag cgtcagacgc atttttccca tttgatgatt
    33721 gtgtaacatt agctcatgaa tatggaatat cagcagtagt tcaaccaggt ggctctataa
    33781 aagataaaga ttcaatagaa gcttgtgaca agtatgatat ggttatggta tttacaggaa
    33841 taagacactt caaacactaa ggaggatatt atgaagatat tggttgtagg cggtggcgga
    33901 agagagcatg ctatatgctg gaaactaagc aaagaaaaaa atgtagaaaa aatttattgt
    33961 gcaccaggta atgcaggaat tgcaaacgta gcagaatgtg taaatatagg tgatactaat
    34021 atagaagaac ttttaaaatt tgccaaagaa aatgaaatag gtctgacaat agtaggacca
    34081 gaagtaccac tagttatggg aatagtagat gagtttgaaa aagaaggatt aagagtattt
    34141 ggacctaata aaaaatgtgc tcaacttgaa ggaagtaaag ctttttcaaa agaatttatg
    34201 ataaaacata acatacctac tgcaaaatat aaagaatata caaacttaga agaagctata
    34261 tcagaaatag atagttttgg atatccagta gtaataaaag cggacggatt agctgctgga
    34321 aaaggtgttg taatacctga aaatagagaa gatgctatag caactttaaa agaaatgatg
    34381 tcagataaga agtttggagc tgctggagat aaaatagtaa ttgaagagtt tttaaaagga
    34441 atagaaactt caattctagc atttgtagat aatgatacaa tagttcctat ggcaagtgca
    34501 aaagaccata aaaaagtaaa caactatgag caaggtccaa acactggggg aatgggaact
    34561 ttttcaccta gtgaaatata tacagaagaa ttagcaaata aagtaaaaga gacagtatta
    34621 gaaaaaactt tagaaggctt caaaaaagat ggacttaatt ttaaaggtat tttatttgtt
    34681 ggtcttatga taactgaaga tggagaaaaa gtacttgaat ataatgtaag atttggagac
    34741 cctgagacac aatctgtttt atttagatta gaaacagatt tacatgagat aatggaagct
    34801 atactagata ataagttaaa agatatagaa ataaactata gtgatgatga agctgtgtgt
    34861 gttatgctta catcaggagg gtatccagac agttatgaaa aagggaaaat tataactggt
    34921 cttgaaaact tggatgatga tatagtagta ttccatagtg gcactaagat gtttgatggt
    34981 aatttggtta ccaatggagg aagagtaatt ggtataactg caaagtcaac tacagttaag
    35041 gatgcagcag aaaaagttta tgaaaacata aagaagataa actttgaagg aatgcactat
    35101 agaacagaca taggaagata atttttctaa aatggaggat aaggtatgtt gaatactgaa
    35161 aataaagact caatggttag aagagtatta gttgaaaaaa gagaaggttt tgaccttgag
    35221 gctaaagctt taaaaaaaga cttagtagaa agtttacaca tagataatat agaaaattta
    35281 agaatattaa atagatatga tgtagaagga atatcagaag aagtttatga aaatgcagca
    35341 aagacaatat tctctgaacc aaatttagat gtagtatatt atgaagaaat accaaaatta
    35401 aatgatgaaa gagtatttgc aatagaattt cttcctggtc aatacgacca aagaggtgat
    35461 tgggcagctc aatgtgtaca aattgtaaat caagggataa gacctgctat taatacagca
    35521 aaagtttata tattatcagg caaaataact gatgaagagt tttctaaaat aaaagattac
    35581 tgtataaatc cagtagatag tagagaagca tctttagaaa aaccagaaac gttaaaaatg
    35641 gaaactgaaa taccaacaac agttgaagta ttagatggat ttatagattt agatgaaaat
    35701 ggattaaaaa catttgtaag tgaaaaagga ttagcaatga ctttaggaga cttacaacac
    35761 gttcaaaaat actttaaaga tacagaaaag agaaatccaa ctataacaga aataaaagta
    35821 ttagatactt attggtctga tcattgtaga catactactt ttatgactga aatagaaaat
    35881 gtaaagatag aagatggtaa gtttaatgat atagtaaaag aagcgtatca aatgtatctt
    35941 aactcaagag acaatgtata tgtgaacaga cataaagata tatgtttaat ggatatagcc
    36001 actgttgcag taaaagaatt aaagaaaaat gggaaattaa atgacctaga tgaaagtgaa
    36061 gaaataaatg catgtagtat aaacgtagat gttgaagttg atggtaagat ggaaaaatat
    36121 ctagtaatgt ttaaaaatga aactcacaac catccaactg aaatagaacc atttggtgga
    36181 gcagctactt gtttaggagg agctataaga gacccattat caggaagaag ttatgtttat
    36241 caagcaatgc gtgttacagg aagtgctgac ccaagaacga ctttagaaga tactttacct
    36301 ggaaaactta tgcaaagaaa aataactaca gaagctgctc atggatatag ttcatatggt
    36361 aaccaaatag gtcttacaac tgggcaagtt gcagaagtat atgatgaaaa ctttgttgca
    36421 aagagaatgg aaataggtgc agttatagca gcagcaccaa aagagaatgt agtaagagaa
    36481 agacctgaag caggagatgt aatcgttctt cttggaggaa aaacaggaag agatggctgt
    36541 ggaggagcaa ctggttcatc taaagaacat agtgaagagt caatcttaac ttgtagtgca
    36601 gaagttcaaa aaggagatgc tcctaacgaa agaaaaatac aaagattctt tagaaataaa
    36661 gaagttgctc aaatgataaa aagatgtaat gattttggag caggtggagt ttgtgttgct
    36721 ataggagaga ttgctgatag cttagatata aacttagact tagttcctaa aaaatatgat
    36781 ggacttgatg gaactgagct tgcaatttca gagtcacaag agcgtatggc agtagccata
    36841 aaaaaagaaa ataaagataa atttatacaa ttagcagtag aagaaaactt agaagctaca
    36901 catgtagcta cagtaacaga tacaggatat ttaagaatgt tctggaatgg aaaagcaatt
    36961 gtagatataa atagagagtt tttagataca aacggagtaa aacaaactac tgatgttcat
    37021 gttactaaag tagatgaaga aaatacattc tttagctcta atgaaatagt aaaagatgtt
    37081 aagtgtgcaa gtatgaaaga caagtttaca aaagtactat ctgaccttaa tgtttgttct
    37141 caaaaaggat tagtagagat gtttgataat acaattggtg gtaatacagt ccttatgcca
    37201 tttggaggaa agtatcaagc gactccaaca caaggtatgg ttgctaagat accagtactt
    37261 ggaggagaaa ctaatacttc tacaataatg acttatggat acaatccaaa ggtaggaaaa
    37321 tggagcccat tccatggtgc cttatatgca gtagtagaat ctgtgtgtaa attggttgct
    37381 attggaggaa attatagtac aacaagactt acattccaag agtattttga aaaacttggt
    37441 aacaatccag aaaaatgggg taaaccattc tcagcacttt taggagcatt ttatgcacaa
    37501 agtaaatttg agatacctgc tataggtgga aaagacagta tgtctggtac atttaaagat
    37561 attgaagttc caccaacatt agtttcattt gctgttgaca cagtagatgc gaagaaagta
    37621 gtatctccag aatttaaaaa agcagactca aaagtagtaa tgttatgtgt aaacaaggca
    37681 gaaaatgatg ttgtagattt tgaggaatta aagagaaact tagataaagt aagagaactt
    37741 atacatggaa ataaagtttt atcaacatat gcattaggat ttgcaggtgt aggtgaagca
    37801 ataagtaaaa tggcttttgg taataaaata ggatttaagt ttagtgaaga ggctgaaaaa
    37861 gcatttacag atgataaatt atttgaggct agttatggaa atatagtact tgaattagca
    37921 aatgatgatt taagtatgtt agaaggatac aattatgttg tgcttggaag tacagttaaa
    37981 gaagctagta tatttatcaa aggtgaagaa cttgcattag atgaattata taaagcacat
    38041 tgtagtactt tagagcctat attcccaact aaaacagaag aagtaaaatc aaagatagaa
    38101 actataagtt atatatcaca aggagaagct aaaaaatcat cattaagtat agctactcca
    38161 agagtattta taccagcatt ccctggaaca aactgtgaat atgactctgc aagagcattt
    38221 gaaagagcag gagctaatgc aagtataaga gtatttaaga atttaactta taaagacata
    38281 gaagattcta tagatacaat agtaaacgaa ataaaatctt ctcaaataat aatgttacca
    38341 ggtggattta gtgctggtga tgagccagat ggttctggta aatttatagc tactgtattt
    38401 agaaatccta gagtgcaaga agctataaat gaatttttaa ctcaaaaaga tggactaatg
    38461 ttaggtatct gtaatggatt ccaagtatta attaaattag ggttagttcc atatggagaa
    38521 ataagagttc caagtgaaag tgctccaaca cttacttaca ataatattgg tcgccatcaa
    38581 gctaagattg ctagaactag aatttcatct aataaatctc cttggttagc tcaaactaat
    38641 gttggagata ttcataatat agcaatttct catggagaag gtaagtttgt tgccagtgaa
    38701 gatgttatga gagaattaat tgctaatgga caagtagcaa ctcaatatgt tgactttaat
    38761 aatgaagcta cttatgatat tgagtttaat ccaaatggtt cattctatgc tgttgaaggt
    38821 ataactagtg ctgatggtag agtgtttggt aaaatgggac attctgaaag aattggtgag
    38881 gaagtatata agaatattat aggtgaaaaa gaccaaaaga tatttgaatc tggagttaaa
    38941 tattttagat aaagctttga tgtttaattg atagctagaa tatataattt agatatttag
    39001 atttaaagag atgtaataat atgatgataa tcatttaata ttacatctct tttttattta
    39061 tctaagaaat aataagttca acctaagtta aaatacaagc tgtgttataa ttaattatta
    39121 agtaaaattg aatatttatt ggagggcaac ataattaatg aaaatattaa taacagggtc
    39181 taatggtcaa ttaggaaaag aattggttaa ccaattagaa gcaattaatc aaagtataaa
    39241 ccaaccaaaa tatgttatat tagctacaac aagaagtgat ttggatatat ccaatcagac
    39301 taatgtagat aattttattt tgcataataa acctgatgta gttgtaaact gtgcagcata
    39361 tacaaaggtt gatgcatgtg aagataatat cgaaattgca tacaaaataa atgctttagg
    39421 agtgagaaat ctagcaatag catcagaaaa agttaatgct aagcttattc acatatcaac
    39481 tgactatgta ttcaatggtt tttctaaata tccatatagg gaagacaata aaactgaacc
    39541 caattctgta tatggaaaaa gtaaacttat gggagaaaaa tttgttgaac aattctcaca
    39601 taagtacttt atattgagaa cagcatggtt atatggtaat gggaataatt ttgtaaagac
    39661 catgataaaa ctttctttag aaaataaaga ggttaatgtg gttaatgacc agtttggaac
    39721 tccaacaagt acagtagact tagcaaaaat tataataaga atcatggaaa cagaacatta
    39781 tggagtttat catgctacat gtgaaggtga gtgtagttgg tatgattttg ccaaaaagat
    39841 atttaaacta aaaaatatag atataaaagt aaatccaatt aagagtaacg aatttaaatg
    39901 taaggctcca agaccactat attctgtatt agataatttt atgttgaagt taattggttt
    39961 aaattctttt agaaagtggg aagaatccat tgaagaatat ttagaaagat atgatataaa
    40021 tgaaaagtaa atgtattatt ttgagaaaag aaaataagat attataaaaa atataaatat
    40081 ttcttttatt tatccgataa tcataatatg acaaaaacaa atttaaggat ggaaaaagat
    40141 gaaaggaatt attttagcag gagggtctgg tacaagacta tatcctataa caaaatgtat
    40201 atcaaaacaa acacttccaa tatacgataa accaatgata tattacccta tgtcggttct
    40261 tatgttggca gggatacaag atatattaat aatatctaca ccaagagata taaaagcatt
    40321 tgaagaatta tttggagatg gaagttcact agggattaac ataacatatg caattcagga
    40381 gaaagcaaat ggaattgcag aagcgtttat aataggagaa gaatttatag gaaatgacag
    40441 agtgtctctt gtattagggg ataatatatt ttatggatat ggatttagtg aaaggttgga
    40501 gaatgcagtt aaaagaaaag gagcaactat atttgggtat catgtaagta atccaaattc
    40561 gtttggagtt gtagaatttg ataaggattt taatgtattg tcaatagaag aaaaacctac
    40621 agttcctaaa tctaattatg ctataccagg attatatttt tatgataatg atgttgtaga
    40681 gatagcaaag ctagttgaac cgtcagatag aggtgaatta gaaataacct ctataaacag
    40741 tgaatatcta aaacgaggaa aactaaaagt ggaacttcta ggaagaggta tggcttggct
    40801 tgatactggt acacataaag gtctattaga tgcttctaat tatgttgaag tggttcaaac
    40861 aagacaggga ttgtatatag catgtttaga agagattgca tatacaaaag gatatataag
    40921 tagagaacaa ttaatgaaac tagccaagcc actgataaaa actgaatatg gtcaatatct
    40981 attaaaattg gctagtgaag atatgtaata tggtagataa aatttattat aaattttatt
    41041 aagggagttt attataatgg gaaaaatcaa tgttataaag actaaaatag aaggattata
    41101 tatagtcgaa ccaaatgtat tttatgatga aagaggatat tttatggaaa gctataataa
    41161 aaaggatttt atagagcagg gtcttgatat gtgttttatt caagataatg agtctagctc
    41221 aagaaaaggc gttttaagag gaatgcattt tcaggttaaa tatcctcaag gaaaattagt
    41281 cagagttaca gagggagaag ttttcgatgt tgcagttgat ttaaggaaag attcacaaac
    41341 atttgggaaa tgggaaggtg taatattgtc tgataagaat aaaaaacaat tttatattcc
    41401 agaagggttt gcacatggat ttttagtttt atcagaaaaa gcagtattta gttacaaatg
    41461 tacaaattat tattacccag aatttgagaa tggttttata tggaatgata agcaaatatc
    41521 tattgagtgg cctttaaaag gaattgaaga aatattttta tcagaaaagg acaaaaaaca
    41581 aaaaagtttt aaagatattt gtacaagacg ttaataaaaa tttattagaa ttaacattta
    41641 ggagaaaaaa tatgaaaaaa atactgataa ctggaggagc aggatttatt gggagtaatt
    41701 ttatacatta tatgcttaac aagtatgtag attattttat tgttaaccta gacttgttga
    41761 cttatgctgg taatttagag acattaatag aaatacaaga caattccaat tataaatttg
    41821 ttaaaggaga tatttcaaat agggagcagg tgtataagct atttgaagaa gaaaggtttg
    41881 atatagttgt taactttgcc gctgaatctc atgtagatag gtcagttgag aatcctgatt
    41941 tatttattaa aacaaacatt ataggaacac aagtactttt agatgcatct ataaaatatg
    42001 gagttaaaag gtatcatcaa atatctacag acgaagtgta tggtgattta ccaattgata
    42061 gaaaggattt attctttaca gaacaatctt ctatcaatcc aagttctcca tattcagctt
    42121 ctaaagcatc agcagattta ttggtaaatt cttattatag aacatatgga ttgttaacaa
    42181 ctatatctag gtgttccaac aattatgggc catatcattt tcctgaaaaa ttgattcctc
    42241 ttatgatttt aaatgctttg gaaaacaaac aattgccagt atatgggaat ggggaaaatg
    42301 taagagattg gttacatgta tatgaccatt gtactgctat agacttaata atacataaag
    42361 gaaatatagg ggagatttac aatataggag gtcataatga aagaagtaat ctagaagtag
    42421 taaaagtgat attaaatctt ttaggtaaat ctgaagagtt aatatcctat gtaaatgata
    42481 gacctggtca tgatttaaga tatgctattg atgcaactaa aatagagaat gagttaggtt
    42541 ggaaggcaaa atatgacttt gatttgggta taaaagaaac tgttaagtgg tatatagaaa
    42601 atgaatcttg gtggaaagct gttttatcag tataacttta aaatttagaa aggggcgttt
    42661 tatattgaat gagataagtt cactaattaa tatattagca ttgactcaat tatctggtag
    42721 taatactaca aatcaatgta attgtacata taataattca tctggatttg atatgattat
    42781 gatgaccttg ttaaaagcat tatcacaaaa taatcaacat acttctaata gctacaattt
    42841 attgtctaat tctgagaatt tatttaatga acttgataat gtagtaaata ataccactag
    42901 tagatttata gatgttgata caaaagataa aaatgtaaag ttgagaattg aaaatgctgt
    42961 agatcaagca tcaaaaaaat ataacgtaga ttcaaatctt ataaaagcaa taattaaagt
    43021 tgaatcagat tttaatccaa ataccgtttc ttctgctggt gctaagggtc ttatgcaact
    43081 tatgccagaa aactgcagag acttaggagt tacagaccct tttaatatag aacagaatat
    43141 agatgctgga actagacata ttaaggaata cattgatatg tttggaggga gcatagaaat
    43201 gggattgatg gcatataatg gtggtcctgg aagaatgaaa agtagaggag tagaatcaat
    43261 ctctgacctg tataaaatgc caaaagaaac acaaaattat attcctaagg ttatgaaata
    43321 ttatagaggg taggctttat tatgggaata aatatagata agctaaacat aagtccaagt
    43381 ataaatatgg aggttaaaaa actaaaagag agtaataaat tttctgacaa attaaactct
    43441 ttaaaacaat cttcttcatt ggaagatata aaacgaaatt tggaaagtgt aaaaaaggca
    43501 ggagaaaggc ttgtacttac tcaaaactat ggcgatatta gtatatataa aaatgcagta
    43561 aaagaatacc taaaatctgt tgtagataat atgtattcac ttgataaaaa tagtagcttt
    43621 tgggagcatc agtattataa gaatgtaaag attgttgata gtaaacttga ggatatgact
    43681 agtaagttaa ttagtgaaga aaaagaaaac atagatattg tttctactgt tgacatgata
    43741 caaggcttat tgatagatat gtatagataa ggttatacaa ggagaaaaat tttatgaata
    43801 gcaaaaaaga ggatatatat gaattgaatt ttgggcaatt aatagaagaa aaatctggtg
    43861 ttatagaaga aaatcaaaat gtttttaatg caaaagtaaa tgtagctgtt tctataggaa
    43921 atacaacaga aacaataaaa aatatattag atttaaaaga aggctctata ataaaattaa
    43981 gtaagaatgt ggatgaaaaa ttagatatat atgcaaacga tagattgttt gcttatggag
    44041 aaagcattat tacaaatgag aggttatctg taagattatc taaaatagaa gatccagatg
    44101 taaattagca ttttaaatag tatcccttta ggctattctg tatgagttta gctaagggga
    44161 tatttttata aaaaatttaa aatatgtgtg aattatataa atatttttat tttatgagcg
    44221 ataactaaat tataagtatg taattttgga ggtgaaacta tggatattaa aaatgtaagt
    44281 tcaaacattg tagtgaataa ttatttaaag aatacatctg gtataaaaaa agtggaagag
    44341 gttaaaaaaa ttaataaaac agacaagata gagttatcta aatttgcaaa ggaaatggca
    44401 agtgtgtcaa atatgagtga tgagaatatt agaaataaaa aagtcgatga aataaaaaat
    44461 gcattagaaa atggaactta caaaataaaa ccaaaagaaa ttgcgaaaaa aatgatagag
    44521 gatatgcgag gataaagtca tgattacaga cttaaaagtt ataatatatg aagaaaaaaa
    44581 tataattagt aagatgatgg aattattaaa agaacaattt gattatatag ttgaaaaaga
    44641 cttagaaaat ttaaatatgt taaatcctaa actagaagat attagcaggg agcttgcatc
    44701 catagaaata aagagaagac aactttttgg tgatgatatt tcaatgagtg aagttgttga
    44761 aaatagtaat gatggatact taaaagaaat atatacagac ttgaaacaca ttcttgcttt
    44821 agctaaaaat caacaagaat caaatgattc tctaataaag aaagaactta tttttacgaa
    44881 aaaaatgatt aatttcataa aaccagctga taagaaaact acaacttata attcttatgg
    44941 aaatattaga aaataaatat taggaggaga aatatggcag gattattttc cattttaaat
    45001 acagctaatt caggaatgaa tgcgcaccaa aaagcaatac agacaatttc tcataatata
    45061 agtaatctag atacagacgg ttattctagg caaaggaccg agtttgccac aaatagtcca
    45121 atgtatatgc ctagtttgag taattcaatt gcaagaggac aattagggac tggagtacat
    45181 gtaacggatg taacaagagc tagaaatagt ttttatgatt accaatttag ggcagaagct
    45241 cataagtatg gtaagacagt ttcaaaatat gattattaca atactataga aactatacta
    45301 aatgaaccat cagactatgg aatatctgca ggtatagatg atttttttaa aggatgggag
    45361 tcattatcaa aggatataaa tagtgacagt aaaaaaagtc tagtggtaga aaacgcatct
    45421 aatttagcaa ctttaataag tgaaagttat aagaagcttg ataagttaaa agaagatata
    45481 gattctaata tagacactga gataaaacaa ataaatgaca tgttaaaaag tcttgaagat
    45541 ttaaataaat ctattgatat tatatctggt tctggctcta caccaaatga tttacttgat
    45601 gaaagagata gaattttaga taacttgagt tttaaactag actttgaaaa tagtgatgtt
    45661 aaaaatatgc ttgcagatgg taaattagaa cttaatgaat taaaaaatcc agatggaact
    45721 tggaaaacag gtatatcagg gaccttacaa ggcttgtttg aaatgcatgg taagattgat
    45781 acatataaaa gcgatttaaa agatgtatct gatggattag ctaaacagat aaatgatgtt
    45841 tataatacgt ctgcaggaat aacagtaaca gattttttta taacttcaaa tgtagatggt
    45901 gaagatatta taaagataaa tccagctata aagagtaacc caaatgaatt aaagcttact
    45961 gctgatgaag cttcaaaaat tgctaagtta aaggatgaaa aaatagatat tggggtggct
    46021 ggtggaaaag taagtacaat aagtgaccac tataaagcct ttgcagaatc aatcggttta
    46081 gattctcaaa aagtaaatca agatgaagca aatcaacgta aaattataaa taatattgat
    46141 aactcaagaa tgagtgtttc aggtgtatct ttggatgaag aaatgacaga gcttataaaa
    46201 atacaacgtt catatcaagc tagtgcaaaa gttatgtcaa cagctgtgca actactggat
    46261 gttgtaataa atggaataat ttaatagaag ggggaattta taatgagagt cagtacaggt
    46321 atgatgtcta gcagctatct aaactcacta caagataatc tacaaagatt ggataaggtt
    46381 aatagacaag ttaatacaac aaaagaaata aacaagctat cagataatcc atataaagca
    46441 ataaagatat taaactcaaa aagtgaaata aagactatgg agacttatgt tgagaattgt
    46501 aaagatacag ggaattggtt agaaactact gatactgcat tagatcagct tggaaaatta
    46561 ttatcagaca taaagaaaac tttggtggca agtggtgatg gtgcatactc agatgatgaa
    46621 ttaaagactc ttagtaatga aactaatgaa aaaatgaaag aaattgcaaa tgctttaaat
    46681 gcaacacatg aagggaagta catattttca ggttcaaata cgggggtacc acctgttgaa
    46741 tgtatagata atgctgatgg ttcagtgagt ttaaagttta attctagtct aaatcttaat
    46801 aaattaaatg actctttgag tatggatata gctcaaggaa taagtgtaga ttataacgtt
    46861 aaattgagta gccttggatt tgacccaaca aaaactgacc catttgaaga gttaaataac
    46921 atatcaaaaa aattagcaaa tccagatgct gatgctataa aagagcttac aacaacttgt
    46981 ttgggcgata tggaacaact aatagaaaat acagtaaatg ttaggtctat atatgggaca
    47041 aaagcaaata cagtagaggc tatgaaggaa aaaaacgatg atagtttgat acagttaaag
    47101 gatattttgt cacaaaatga agaaatagat tatggtgaaa aacttgttca attaaaggca
    47161 gcagagttaa cttatcaagc ttcactacaa acaggaggaa agttatttaa tgtatctata
    47221 ttagattaca tataataaaa taacgcagat atgatgaagg ttacattaaa aaaaggtata
    47281 ttaggttttg aaaatttaaa agaatatgag cttttagata tagaagataa tgattattta
    47341 aaagaattta attctactga agaagaaggt ataggatttg ttgttgtatc tccatttgag
    47401 attatcaatg aatatgaaat agttttaaat caggaaacaa tagaaaaact agaagtgaaa
    47461 tctccaaagg atgttgtatt atttaatata attactcttg gtcagacatt tgaagaatca
    47521 actgtgaaca tgaaagctcc tatagtgata aatataaaaa ctaattttgg aatgcaaata
    47581 attttacagg atgataaata ttcaataagg catccattat tgagaggtga taatggatgc
    47641 tagtaatttc aagaaaaaaa gatgaagcag tacttatagg agaaagcata gaagtaaaaa
    47701 ttgtaggagt agatggaaac aatgtaaaac tagctatatc agcgcctaac aatataagta
    47761 tattaagaaa agaaatatac gaaaaagtaa agagtgagaa tataaaagct acaaataaaa
    47821 atataaaaat tttaaagtca ttaaaataat aagcttggag gaagtaatat atgtatggag
    47881 aaaatcctta taattcttat aaacaaaatg ctgtttttat ggcatcaaag gaacaattgt
    47941 tacttatgct tgttgatgga gcagtaaaat ataccaaaat agccaaaaca gctatcttag
    48001 ataaaaatac acaaaaagcg catagagagc ttataagagt tcaggatata tttacagaac
    48061 taatggttac attagaccaa aatgcaggtc aatgggcaaa ggatatgtac agagtttatg
    48121 attttgtaag atatgaactt tcaagagcta atattagaaa agacattcaa ataatagata
    48181 atgtgttgcc tgtaatagaa caaattaaag atacttggca tgaagctgat aaaaaaagta
    48241 aagaagaaag aagtaggtac aaataatgga attaaattta gctgaattag ataagttatc
    48301 aaaagaggaa ttactattga tgcttgtaga tggaacagta aaatatacca atatatccaa
    48361 agaagctctt ttaaataacg actatttgaa agcacataat gaacttgtaa gagttcaaaa
    48421 tatatttaca gaactaatga ctacattaga ccaagatgca ggtcaatggg caaaggatat
    48481 gtataaagtt tatgaattta taaaatctga attagcaata gctgatgaaa ataaagatat
    48541 taaaataatt gatgatatat tgccaatagt aaaacaaatt agagatacat ggcatgaagt
    48601 ttacaatcaa ctaaaaatat aattggatgg agggataaag gtatgtcaag tataagtcct
    48661 ataagagtta caggtctttc aggaaatttt gatatggaag gcataatcga agctagtatg
    48721 attagagaca aggaaaaagt tgataaagca aaacaagaac aacaaatcgt taaatggaag
    48781 caagaaatat atagaaatgt tatacaagaa tcaaaagatc tttatgataa atatctaagc
    48841 gtaaattctc ctaatagtat agtaagtgaa aaagcatact cttctacaag aataaccagt
    48901 tctgatgaaa gtattatagt agcaaaaggc tcagctggtg cagaaaaaat aaattatcaa
    48961 tttgcagttt ctcaaatggc tgaaccagca aaatttacta ttaaattaaa ttcaagtgaa
    49021 cctattgttc aacagtttcc tccaaatgct agtggagcga gttctttaac tataggagat
    49081 gtaaatatac caatatctga acaagatact acaagtacta ttgtaagtaa gataaactcc
    49141 ctttgcgcag ataatgatat aaaggcttct tatagtgaga tgacaggtga attgattatt
    49201 tcaagaaaac agactggttc gtcatcagac attaatttaa gagtaattgg aaatgacaat
    49261 ttagctcagc aaattgctaa tgataatggt atcacattta taaatgatgc tggtggaaac
    49321 aaagtggcaa atgtatatgg aaagaatcta gaagctgatg taactgatga acatggaaga
    49381 gtaactcata taagtaaaga acaaaattca tttaatatag ataatattga ctataatgta
    49441 aattcaaaag gaactgcaaa gttgacttct gtcactgata ctgaagaagc tgttaaaaat
    49501 atgcaagcat ttgtggatga ttataataaa ctgatggaca aggtctatgg tttagttact
    49561 actaaaaaac caaaagatta tccgcctctt acagatgccc aaaaagaaga tatgacaact
    49621 gaagaaatag aaaaatggga aaagaaagct aaagaaggta tacttagaaa tgatgatgag
    49681 ttaagaggtt ttgttgaaga tattcaatct gcattttttg gagatggaaa aaatattatt
    49741 gcattaagaa aactaggtat caatgaaagt gaaaattaca ataaaaaagg tcaaatatca
    49801 tttaatgcag atactttttc aaaggctctt atagatgata gtgataaggt atacaaaaca
    49861 ctagcaggtt attcttcgaa ttatgatgat aagggaatgt ttgaaaagct aaaagatatt
    49921 gtatatgaat attctggaag ttcaacttct aaacttccta aaaaagcagg tatagaaaaa
    49981 actgcttctg ctagtgaaaa tgtatattca aaacaaattg cagagcaaga aagaaatata
    50041 agcaggttag ttgaaaaaat gaatgataaa gagaaaagac tttatgctaa atattcagcc
    50101 ttagaatctt tgttgaatca gtattcttcc caaatgaatt atttctcaca agcacagggt
    50161 aattaattat ggataaatta aaagaaaaat taaatttata taaagatata tctttacaaa
    50221 ttataaattt gattgaaaag gaagaatata taaagataag tattaagtta ggtgaaagac
    50281 aagagattat aaatagtgta agtgaaattg atagaaatga ttttatacag ctttataata
    50341 gaatggaatt aattgaaatt gatagcagga taagagatat tttacaagga caattattag
    50401 aagtaaaaaa agaattacat gagtataagc ttactaaaca agtgaacaca atgtattata
    50461 acttaaatag agaaaaagta aatattttta ataaaaaagt ataaagttat gtaccatctt
    50521 gtccgattat ataaatgaag aattaataaa aaagattaaa agtagaaatg acaaggatgt
    50581 caactatact aaggagggta aaataatgag agttaataca aatgtaagtg ctttgatagc
    50641 aaataaccaa atgggaagaa acgtaaatgc acaaagtaag tctatggaga agctatcttc
    50701 tggtgttaga attaagagag ctgctgacga tgctgctggg cttgctatat ctgagaaaat
    50761 gagagctcaa ataaaaggtt tagaccaagc aggaagaaac gttcaagatg gtatatctgt
    50821 tgtacaaaca gcagaaggtg cattagaaga aactggtaac atactacaaa gaatgagaac
    50881 tttatcagta caatcttcaa atgaaactaa tactgctgaa gaaagacaaa agatagctga
    50941 tgagttacta caattaaaag atgaagttga aagaatatca agctcaattg agtttaatgg
    51001 taagaaatta cttgatggaa gttctacaga aataagatta caagttggag caaactttgg
    51061 aacaaatgtt gcaggaacat ctaacaacaa caatgaaata aaagttgctc tagtaaatac
    51121 ttcaagtata atgagtaaag caggtataac aagttctaca atagcaagct taaatgcaga
    51181 tggaacttct ggaacaaatg cagctaaaca aatggtatct agcttagatg tagctcttaa
    51241 agaattaaat acatcaagag caaaattagg ggcacaacaa aatagactag aatcaactca
    51301 aaacaactta aataatacta tagaaaatgt tacagcagct gaatcaagaa taagagatac
    51361 agatgttgct tcagaaatgg ttaacttatc taaaatgaat atattagttc aagcatcaca
    51421 gtcaatgctt gctcaagcta atcaacaacc acaaggagtt ttacaattat taggataaaa
    51481 taattttgta tattggatat agaagaaagg gtaaggcttt gctttactcc tttctttttt
    51541 tacaaatata cttttgaaag gaaaatttat atgttactta gtatagttat gattgttaaa
    51601 aatgaagaaa aaatacttga aaaaacttta aaatcattaa ccacattaag aaattctata
    51661 gaaagtgaac ttataatagt cgatacaggt tctacagatg atactataaa aatatctaag
    51721 aagtacacgg aaaaagtgta ttttcataat tggaataatg atttttctag tatgagaaat
    51781 atatcaatat cctatgctaa aggtgaatgg ttacttatat tagatgcaga tgaaatacta
    51841 attgattctt caactattgt aaaatttttt aaagatggtc ttgataaaaa atttaattct
    51901 gcttcaatac aattaaaaaa tctttactca tatgataaaa aattatatgg atattgttcg
    51961 gtgcttagac tttttaaaaa cgttgatttt agataccatg gtaaagtaca tgaacaacca
    52021 atatacaaaa accctatatt taataatgtt gctgattttg aacattatgg atatttgttt
    52081 gaagatgaag aaataagatt aaataaggtg aaaagaaatg aaaaactatt atttcaagag
    52141 ttaaaagaga atgataattc tccatataca aactatcaat tagggaaaaa ttttattata
    52201 ttaggaaaat atcaggaggc tttatactat cttgagaaat cttatgaatt atattctaaa
    52261 ctagaattgg cacctggtta cttgataaca agccttgtaa aaacatattt atatttagga
    52321 aaacataaga agtgtgaaag attgtgctta aagtatatta agaaagacat gaataatatt
    52381 gatatatatt attatattgc acaagcacaa gtagatttag gaaagtatga aaatagtata
    52441 gattcgtata agagatatat ttacttgtta gataattatg aaataagtac acaagcaaat
    52501 agtttatttt cagacactga tactgtaggg cttagagatg aggctattat tacactgata
    52561 aagatttatt ataagcttga aaaatatgag tttgtaattt cagagtataa taacattgaa
    52621 gatgtggaaa agaaaaagaa tgtgtacttt agcttattta tgtcactata taaattgaat
    52681 agatttgaag atataaaaaa ttattataaa gaagtttcaa attctaaaat tgaaaaaaat
    52741 agtttttata gaaatataga agaagttata aataatatta aagaggatga aaaagagtat
    52801 gtatataaaa tcctttgtga cattgaaggt aattatggca ttttaaatca aataaggata
    52861 aataaatgtg tatctataga taaatgtaaa gaaatactca atgaagaaaa ggaaataatt
    52921 tatgcatata ttataaaaat agcttttgaa gagaagattg atttactaga tattttttat
    52981 gaaatggaat atgtatggat agagaaatat ctaaaatatc ttttagcatt agaaagaagt
    53041 tttaatttag tactatataa gtacataatt agtcgtccaa atacatcaga tatggaaaag
    53101 ataagagtat ataaagctat atctaaagta gttttagaaa gtataagctt aagtgatgaa
    53161 aaatataagg agatttttta tctttatata atgtattctt ataagtacat aagatacata
    53221 tatagcaatt taagtgattt tgaattaata aaatttgttt gtaatgattt agataagttc
    53281 actatagaat ttaagcatct acttgatatt aaaaataaag taaataatgc taatgaaaaa
    53341 ttagagtata tacatagtat gaggaaatta ctaaatgagt atccttttta taataaaata
    53401 ataaaaatac ttataggtga attagaagaa aatataaaag aaagtgaaga atttaaggat
    53461 ttaaaagata gttttattat tagtatagaa aatatgattg aaactggcaa aataaatgat
    53521 gcgaaattat tggtagatga ctattcaaaa acatttgtgg atgatataaa gattttaaat
    53581 ataaagggaa ttttatacat gtttgaaaat aagcttgata aagctgattt tatgttaaaa
    53641 aaggcattat cattagatgt agaaaatgaa gatactatat ataatataga atacttaaaa
    53701 agtttaagat aagtcaaaaa taggagaatt gaagaatgaa tataccaata gtggttaatg
    53761 aaaaatctaa agacataata aaagattggc aatatacatg tacaaatgaa gatataaaat
    53821 ttacaagcat aataatattg acatataatc aaatagaata tactaaatta tgtattgaaa
    53881 gtattaggaa atttacccca aagaataaat atgaaataat aataattgat aataactctt
    53941 ctgatggaac agttgagtgg ttaaagggac aatctgatat aaaatctgtg tataataaca
    54001 aaaacttagg atttccaaaa ggatgcaatc aaggtattga gttagctact ggtgaaaaca
    54061 tattgttgtt aaataatgat gtaatagtta ctccaaattg gctctataat ttgaataaag
    54121 ctttatggtc tcaagataat ataggtgctg taggacctat tacgaatgca tgttcatatt
    54181 atcagcaaat tgatgttgat tataagtcaa ttgaggacat gtttatattt gcacacaaaa
    54241 taaataaatc taatattaac ctatggaaat atagattgaa gttagttgga ttttgcatgt
    54301 taataaaaaa aactgttctg gataatgtag gggttttaga tgaattattc acacctggaa
    54361 attttgaaga tgatgattta tcttttagga tgatagagtc aggatataag ttattattat
    54421 gccaggatac ttttatacac cattttggaa gtgtgtcttt taaagaaaat cgtaataaat
    54481 atacagatat aatgtatatt aatagaagaa aatttgaaac taagtgggga tttaatccag
    54541 aatatagtgg aatgataaga acagatttga tttctaaaat agatgatagt ttggaggcaa
    54601 atattaatgt tttagaaata ggatgcggta taggggctac tcttttagaa ataaaaaata
    54661 tatataaaaa tgcatcaata tatggaatag aaattagtga gtcagcaggt aaacttgcaa
    54721 agtatagtgc agatgtactt atagcaaata tagaaaaagt aaaattggat tataaaaaag
    54781 atttttttga ttatataata ttgggagatg tacttgaaca tttgattgac ccatggaaga
    54841 tagtcaatga attgaaacaa tatctaaaga aggatggtta tctggtatct agtataccaa
    54901 atattatgca tgtttctgtt ttaagaaatc ttgtgttagg taattttaca tatgaagatt
    54961 caggaatttt ggacaagact catttaaggt tttttacatt aaatgagata acaaaaatgt
    55021 ttaatgatag taattacata attaatagta ttacagctac tagtatgcca ctttcggaaa
    55081 ttgataatag cttcattgat acaatatgta aggaaagctg taaagaaatg agacaacagt
    55141 acgaatctta tcaatatata gtaaaagcct ctaaaatcct agatactaaa agatattcta
    55201 gtattagtat gattaattta aaatacgctt taatgagaat tgataatgaa ttagatgtag
    55261 atagtaattt aagttatata tttgataatt ataatataac tgaaccatgt tttgttgatg
    55321 atattgaata tctaattgat acatttgtga taaataaagc aactctatta aatagattag
    55381 gagttgaggc atttaacaga ggtctaggag attttagtat aaacatgttt atgacagtat
    55441 tagagatgga tagagatgat attgactcaa tatataatat aacaagtgta ttatgtgaat
    55501 tagaagaatt tgatactgct tataatttaa ttaaaaatag tagcgaaaaa gtacagagtg
    55561 aaagtgatat acaagagata ctttgtttta ttgaggggaa gaaatatgaa taatgataag
    55621 atatgtttta taacctgtgt aaatgatgaa aggctttatg aagaatgtct tgtatatata
    55681 aatagcctag acattcctaa aaactttagt atagaaacag tagctttaag aggagccgat
    55741 tctattgcct ctgcttataa taaagctatg agagaaacag attctaagta taaggtatac
    55801 ttacatcaag atacttttat aattaataaa aatttcatac atgatatttt agagatattt
    55861 aaaaaaaata cagatgtcgg aatgattggt gtagctggag taaaagatat gcctgtgaat
    55921 ggaatttggt gggattctga taaaaaagca gggaaagtat atgatagtca tacaggtaaa
    55981 atggatattt atgaatttag taactttgaa gaatgtttta atgaagttat ggctatagat
    56041 ggattaatta tgattactca atatgatgta ttttggagag aggataagtt tgatgggtgg
    56101 catttttatg atttgtcaca gagtatggag tttagacaaa ataaatacaa agttattgta
    56161 ccaaaacaaa ataagccttg gtgtatgcat gattctggag tagtaaatat aaataatgga
    56221 tatgatgaat ataggataaa atttgtaaaa gagtacataa atcttgattt atatagagaa
    56281 aatttttatg aatttgataa gaagaaagca agtaccatac ttaagagtaa taagcatgta
    56341 atggattgta tgaaagagga gcttacagaa caattaagat taaagaatta caaggatgtt
    56401 ttaggtattg tttctaaaat tgctcatttt tctgttttta atcatactgg tttgtattct
    56461 tgtgaagaat gtgagagagc attgctagaa tgtgcaaata atttaccaga aatagaaaat
    56521 acgaaattat ttacaaaaaa agatttaaaa agaagaaaag tattacatgt tttaagtgaa
    56581 ggatattcaa caggaggtca tacaagacta gttaaaaatt ggattgaaat tgacaaagac
    56641 tctgttcatt cagttgtaac tacatggcaa tcagatacac tgccagactg gttattaaaa
    56701 gcaataaatg atagtggtgg cgaagttata tctttggatt taatttcaga tgattattta
    56761 aaaagagctg tagctttgag gaaaatagct tatgactggg ctgatatagt tattttatat
    56821 gttcatatgt gggatacaat acctgttgtt gcttttggag ttgatgggaa aatacctatt
    56881 ttacatgtta atcactatga tagtactttt tggttaggga caagtattgc agatattgtc
    56941 attgatttta gcgaaactag tcaattaatt acattagata aaagaggcat agataaatct
    57001 gaaatattac caatgccatt aaaagaaaaa gaagtatttt caaaatctga agttagaaaa
    57061 cgatataatt tagaggatga tgtgacaata atattgacta ttgctagtga aagaaaatac
    57121 aatagtgtaa atgatattaa ttactttaaa attgctaaaa cattgattga aaatacagat
    57181 aatacaatta ttattgttgt aggagttgat acagagaatc tctattggaa aactttaagt
    57241 aatgttacag ataatagagt tatatgtttt ggaacaacag caaatataga tgatttttat
    57301 aagatttcgg atatatacct agagtctttc atggtaggaa gtcatacttc aaaattagat
    57361 gcaattttat atgatttaat tcctgttaag tttaaaaatg aagtttcacc aatttttaca
    57421 aatatgtgga attttataga taagtttgat tataagaata taaaagaggt tatagacatg
    57481 ataagaaggt acaatactag tgaatttgac agggataaga taaaagcaaa acaatcggaa
    57541 ataaaacatt ttgttataga taaacattgt attgaaataa aaaactatat agacaaaata
    57601 tataatgaag ttaatcatca taaagttaag tatgatttat ataaaaatga tgaaatcgag
    57661 gactatcagc tttttgtagc attatatggc tatatggtaa aaaataaaaa catgtcatag
    57721 gtggtaaaat gaacaatatt catatcaata aatttgaaaa aagctgtgaa aaaaactggg
    57781 attattttgt agaaaataaa tctataaatg gtacatttct gcaaactaga aatttcctta
    57841 attatcatga ggagggaaaa ttcactgacc actcattaat aatatgtaaa ggtgaagaaa
    57901 tactagcagt cgtacctgca tgtgaaactt atgaagatgg tgaaagaata tttttttctc
    57961 atttagggag tacttttggt ggcattataa taagaagtgg ttttaatgat attaggcatg
    58021 taaatgccat tacaaataag ttagaaatat atttacagga acaaaatttc gataaagtat
    58081 atttaaaaaa tacatcaaga atattttgta aagaggatac ttcattacta gaatattttt
    58141 tatttaagaa taattacatg ttttatgatg aattaagtat gtttttagaa ttaagtaagt
    58201 ataaagaaga tatattagcc aattttaaat acagtaaaag aagagatttt aaatattctt
    58261 tgaagaataa tcttaccttt aaaagactgt atagtgatga agatatagtt tgttttttta
    58321 atttactttc taattgttta gatagtaaag gagctaaagt aatacattca gtagaagaac
    58381 ttttggagtt taaaaataat agattaaaag atattgtaga attttatgca gtatatattg
    58441 atgacattat gatttgtggg agcatggtat ttaactttca agaaagagtt tatcatactc
    58501 aatatctagc atcaaattcg acatataata aatattatcc aatgatattt ttatactata
    58561 atctaataaa agatgcttta gagagaaatt ttaagtatct ttcttttgga attagcactc
    58621 taaatagagg caaatactta gatgagggtt tagctacatt taaagaaggt tttggttcaa
    58681 gtgcaatttg taacagaaca tactataaaa atataaataa gtgagaatca tgttttatag
    58741 agtttttaga gtatagtaaa tatctagtac tataatatta cataaaaata attagtttat
    58801 aaagaaggtt tgtatatgaa aagattaatg attttaggct caattaagta ttttgagaat
    58861 attgttatgt cagctaaaag agagggaata tacacaattg tttgtgataa tagaattgat
    58921 actcctgcga aaaagatttg tgatgaagca atagatgttg atgtatttga ttttgataaa
    58981 ataaagaata tagctataga taaaaagata gatggaattt taactggatt tacagattct
    59041 ttaatgaagc catatgttta tattgcaaat gaactaaatt tgccatgtgt gatttcttgc
    59101 aatcaacttg aatctgtaac taataaggct gttatgaaaa attattttaa aaataatgga
    59161 atacctacaa ctgattattg tattattgaa agtttgaaag atttagaaaa aatacaagga
    59221 ttaaattttc cacttgtaat aaaacctgtt gatggttatg gttcaagagg tgtatatttt
    59281 gtatcaaaca tagaagaatt aatagaaaaa tttgaatatt ctaaggaagc ctcgcaagat
    59341 ggacaagtaa taattgagga attttatgaa agtgaggaaa tacaaggact agcttgggtt
    59401 cataatggag agtcacatgt attttatatt ggagatagag agcttgtaaa tatacataca
    59461 ggaagagctg gaaaaccaga tagattaatt tatccatcaa agtattgttt tcaatatgaa
    59521 gaagaaataa aatccatata tcaaaatata acgcaggctt ttggcataaa aaatggacct
    59581 ctttatgtac aaatgttagt gggagcatat ggaataaagg tatctgaagt aatgccaaga
    59641 ttacctggag gttgtgacta tatggctatt tctcaaataa cagatttaga cataggaagt
    59701 ttatttgcaa actttagtgt gaataatgaa gtaaattttg atgaaataaa gaaatataat
    59761 atgcatctat caaaatgtgt atatgcatta ccaatataca taagacctgg cacaataaaa
    59821 aagataaata atatagataa aatagaaaac ttagattatg tcactcaatt tctattacta
    59881 gtaaaagaag gagatacaat aggattatat gaagatgaga gacaggattg tggaagagtt
    59941 tatggagtag caaataatgt atttgatgca aatataaaga agaaatgtat tcatgaaatg
    60001 atagaaatac ttgatgaaaa taatgaaaat atgatagaaa atttttaaat aagggagtat
    60061 gatagatatg aagctaataa ctcatgaaca aattatgtca ttaaacattt ctcagaaaca
    60121 aggatacgag tggataaaag aatccttttt aacaaaaaaa gattgtcaat taccaccaaa
    60181 aataagcatg gtagaagaag ggcatgtatt ttacaatgta atgccgtccc taaatcataa
    60241 tcataagatt ggtggaataa aaatggttac aagattgcca gggagaaatc caagtttaaa
    60301 ttcagagata tttctatata atatggaaga tgctaaatta aaggctattt tagatggcaa
    60361 ttatattaca gcttttagga ctgctgctgt tgctgccttg gctatcgata catttgctaa
    60421 aaaagatttt aatactattg ctattatggg tttaggtgta actgcttctg ctataatgaa
    60481 tatgctttca tatactctta aagataaaaa tataaatata aagttactta aatataaaga
    60541 ccaagcagag tcgtttgtaa aaaagtatga aaaaaatgaa caatttagtt ttgaaatatg
    60601 tgacacacat gaagaactta ttgtagattc agatgtagtt atttctactg tgacatatac
    60661 agatgaatat ttatcagaat ttaaatggtt taaaaaaggt gctttattat tacctgtaca
    60721 tgttatggga tttggaaatg ttgattatct atttgataaa gtatatttgg atgattataa
    60781 tcatttgaaa catctagaaa atatagatag atataaatat tcttgtgaat tttatgatgt
    60841 tttaagtaaa caagctaaag gaagagaaaa tgatgatgag agaataatat cttacaatat
    60901 aggtttgtca atacatgata tattatttgc aaataaaatt tacgaattgt gtgaaacact
    60961 aagctgtgaa gaaatagaat taaaagaacc aaaagaaaaa tattggatat agtttatttc
    61021 attcatattt acaatagttt attgtaaata tgaatatgaa gtaatatatt gttagaaaat
    61081 tagcatgaat aggatagata aatttatgga taaatataat ttaattaggt tcgtatctat
    61141 tggaaacgaa tatataggaa atttagttgc attagaatca aataaagcaa taccttttga
    61201 tataaagaga gtttattaca tatatgatgt accaaacaat gtaaagagag gatttcatgc
    61261 acacaaaaac ttggaacaag tactagtttg cctaaatgga agtgtgaaga taaaatgtta
    61321 tgatggtgta aaagagacta tatttaattt acataaaaat gatgttggat tatatatagg
    61381 aacgggagtg tggcatgaga tgtttgattt tgatgaaaaa actgttttaa tttctatagc
    61441 atctgaacat tataatgaag aagattatat tagagactat aaagaatttt taaagtattt
    61501 aaataatatg tagttattat acagttagtg atgtattttc ttaattaaat aaatttaaga
    61561 tagccacata gagaatagat agattaggat gtgaatttat tgttggttaa atttaataat
    61621 ttattaaaac agttccaaac ccataaagaa gaatatgaac agaagattaa ggatgtaatg
    61681 gaaagtggat attatatcct tggaaatgaa gtaaagcatt ttgaagaaga atttgctaac
    61741 tatgtaggta gcaaatattg tgttggttta gccagtggtt tagatgcact gataattgct
    61801 tttagagcat taggaataag cgaaggtgat gaagtaatcg tgcaatcaaa tacatatatt
    61861 gctagtgtta tgggaatcag tataaatgga gcaacaccag tatttgtaga accaaatgaa
    61921 tattataata tagattcatc taagatagaa gaaaagataa atagcaaaac aaaagctata
    61981 ttagtagtgc atttatatgg tcaagcaagt aatatgaaag atatacaaga attatgtgat
    62041 aagtataact tgtatttaat tgaagattgt gctcaatctc atggagctaa atatgatgga
    62101 aaaatgacag gaacatttgg tgatataggt tgttttagtt tttatccaag taaaaatttg
    62161 ggtgcatttg gagatgcagg agctatagta actagtaatg aggaaatagc tgataaagtg
    62221 aaaattctta gaaactatgg ctcagaaaag cgatattata ataaatttgt cggatataat
    62281 tcaagattgg acgaaattca ggcaggttta ttaagagtaa aacttaaata tctaaatgaa
    62341 attgaaattg aaaaatcaaa aatcgtagat agatatctta atgaaattaa taatcccaaa
    62401 gtcatacttc caaagataga aaataattgt actcatgtat ggcatttatt tgttttacaa
    62461 gttgaaaaac gagatacatt tatggaatac ttaaagaaaa atggtataga gtctataata
    62521 cattatccga taccaccaca tctatctgaa gcatatgctt atttgggata taaaaagggg
    62581 agttttaata tagctgagaa ctattcagat aaagttgtta gtataccttt atttatcggt
    62641 atggaagatg aagaagttag ttatataatt aaaattataa atgaatatta aactactcat
    62701 aataatatca aaaataaatt ttttatatat catttattta agtttcgtta attgacattt
    62761 ttaaatattg atatattgta caaataaaat tgaaatatat ggaaaaatat agaattaaga
    62821 tgagatttgt cttatatttt tataaattaa aaatattttc aaagagttta ttataaaatt
    62881 ctagagtata gtgtttataa tatttgtaat tattggtaac taaatataaa atataaaata
    62941 tttgattata aacaaaaaag atatttaaaa aatttgttat ttattgtata cttaagttaa
    63001 aactaaatag gcaaatctag agaaatctag tgacgcaaag ctatagggac taaggtttat
    63061 atacatgaac tatgtcagcc agttgccaaa aagagtccta ggtgtattgt atacctaaga
    63121 aaagtctaga atgactgcct ttttggcagt cattttgtta tgaaaaaatc actttatttc
    63181 agtagaaaat acctataatt aacatacttt accaaattat aacataaaat aaagaaaaat
    63241 tatcttaaaa agttactatt ttacaaaaaa gagcaacttt tcgaagaaat atttaaatac
    63301 atattaaaat ttttttatat tttcatggga cttcattgaa aaaatattag ttttcttact
    63361 aaaatgatac attattgtat taatgtaatg gaaatgcgat taatttaaat gaataaagaa
    63421 gtcatttttt gtaatatagc aacttcattt ttttattaat aagcaaaata aataaaatat
    63481 attttgagga ggagtgagtg tgaatacata tgacattata aaaatgggat tagatgcaac
    63541 taatttaaga agtcagacaa tagcaaataa tatagcaaat ataaatactg aaggatataa
    63601 gagacattat gtaacttttg aagaaacatt aaatgatgct atgcccaaaa tagaagaaaa
    63661 aacagataat tctaaaggat taagagtgga tggcaataat gtagatatag aagaagaaaa
    63721 agtaaaccaa gcaatgacaa cattacaata taatgctttg ataagttttg caaatggaaa
    63781 aatagcaatg actaaatcaa taataagtgg gaggtaatta aaaggtgagt gtgttcagtg
    63841 gaatgagaat atctgctagt ggattaacag cagaaagctt gaaaatggat atcatatcgt
    63901 ccaatgtagc taatataaat gccacaagag gtccaaatgg agaagcatat aggagaaaag
    63961 ttgtttcatt tgaagaaaac tatgataata aattaggtat gctaggagta aaagttacat
    64021 ctgttgaaga tgataaatca cctcttaaaa aagtatatga cccatctcat ccagatgcaa
    64081 agccaaatgg atatgtagaa tatccaaatg taaatatatt ggtagaaatg acagatttaa
    64141 taacagcttc acgagcatat gattctaacg tagatacatt gaatgctcag aagtctatga
    64201 tatcaaaagc tttggaaata ggaaagtagg gataaattat gccaattaca caaattaaca
    64261 atttaatgca aggtgcaaag ttagataatt tgattggaga aacaaaacca ttaactctta
    64321 ataaagaaga aaaaaagaat tttgaagatg taataataga tactatagat aaagttaatt
    64381 ttcaacaagt gacagcagat gatatgaaag aaaaatttat aaaaggcgaa gatgtttcta
    64441 tgcatgaagt tatgttaata ggtcaagaag cacagctatc tatgcaatat ttaatagaag
    64501 ttagaaataa gattcatgat gcatatcaag aaatgaataa ggtacaaatt tagccttttg
    64561 aacaggagta ataatcaatg atagccagtt ttaaaaataa gattaaagag caagttgcta
    64621 aatctaggac aaagataagt tctctaaaaa agggaactaa aatagcatta ggtatagggg
    64681 ttattgctat atgtttagcg ctagtattta cagcaatatc tgcgagcaaa aataagtatg
    64741 cagtcttatt ttcagaacta gatgttcaag atgctgcaga tatatcagca gaattagagt
    64801 ctaaaaagat agatactaag gtaaagggaa gtacgattta tgtacctaga acagaagttg
    64861 ataagttaag gctggagtta gcaccaagtc ttacaagtgg ttctaaagga tttgcactaa
    64921 tggatgatag ttcatcaata ggacttactg atgaagagtt tcagattaag aagcaaagaa
    64981 tgatacaagg tgaaatagaa aaaacaataa agagttttcc acaagtggaa gacactagag
    65041 tacatataac atttggagag tcatcagtat ttgagaagga ggctgttcca gggagtgcag
    65101 cagtttattt gatgctaaaa ccagggacga ctttagaaaa aaaccaaata aagtctgtta
    65161 tggcacttat atcaggaagc gttacaaata taccagagaa aaatgttcag gttattgata
    65221 acaaaatgaa tttattatct gaaggtattt tggaggatga aaatgttaat gaaaataatc
    65281 aaccaataaa tagtggcatt agtgttgata aaaataaggc atctgaacaa gcattgaata
    65341 aacaactaga aaagtctatt ttagaaatac tagaaccaat atttggtaag ggaaaggtga
    65401 aagctacagt aaatgctgat ttaagttttg atacagctga aaaaactgag ataaaaattg
    65461 accctgataa agttgcaata aaagagacaa ggtcgaaaaa ttcatctaaa tctgctacaa
    65521 ataatgttca aggtgtagat gctaacatga ataaccaagg aaataacaat ggtactaata
    65581 cagaagatag tttagatgag agttttgagt atgaaacagg taagattgaa actcatacta
    65641 tagttgcgcc tggagaactt aatagattga cagcttctgt tgcaatagat ggaaaaatag
    65701 ctaaaggtgt tcaagctgat gtagaggata ttgttaataa tgctataggt atggatggag
    65761 cgaggggaga tactcttagc gttgtttcaa tggtatttga cccagaaggt aagaaagagg
    65821 ctaaacaaga gctggaagag attaaaaaag aaggatttaa aaagaacata ataaaagcag
    65881 ttattggagt agtggcagta gtagcaattg gagctattgg atacttgata tataagaaaa
    65941 gaagtgaacg agaagatatg gattatgaag atgaagatta tatttctaaa tctgattctg
    66001 ttgatagaaa agataatcct ctattaggag atgacccaga actgacatta gaggaagctg
    66061 ttaaaatgta tgcagaagaa aagccagacc aagtaacaga gataataaaa acttggttaa
    66121 atgagtaagg gggatagaaa gtgtccacgg aaattacaaa tgttaatgcg tttgacttaa
    66181 gtgatataaa tgagagtgat aagaaagaga agatagaagg tgagggttta aaaaaagctg
    66241 ctgtattatt aatgacatta ggaccaaatg tttctagtga tataataaaa agcttgcctg
    66301 ataaacaagt tcaaaaaata ggtttggaaa ttgcaaatat ttcttcaata gcttcaaaag
    66361 aaagaagaga aatcttaaaa gagtttgtag aaataaatag ggcaaaagat tatgttatag
    66421 aaggtgggct tgaatatgca agagagttgt taagcaatgc tttaggaaat gccaaagcaa
    66481 acaaattact tgaaggtata tcaataaata caagcacaaa gccttttaaa catattataa
    66541 aactagatgt aaagaaaata ttagaaatac ttaggaatga aagtgcacaa actatagccg
    66601 ttttacttgc acatatggag ccagaaaatg gagcagaagt tttatcatac ttagattttg
    66661 atttacaaaa tgaagtagct atgaggataa gctcaatggg ttcaatatct ccagaagtaa
    66721 taaaagtaat tgaaagttca ttagaagata aattacactc aatgagtggt gatgatttta
    66781 aggattatgg aggagtgtct accttagttc aaatattgat taattctgat agaaaaacag
    66841 aaaagaatat tttgggaact attgaagaac aagacccgga tttagcagct caaattaaat
    66901 ctcatatatt tgtctttgaa gatattgtca agttagatga tataagtata caaaaagtgt
    66961 taaaagaagt gactatgaaa gatttagtat atgccttaaa aggtgtggat gatgagattt
    67021 cagatgctat atatagaaat caatcttcta gggcagcaga ggcacttaga gaagaaatgg
    67081 aaatggttgg tgtcataaaa gttacacagg ttgaggctgc tcaacaaaag atagcaaata
    67141 tagtaagaaa acttgaaaga gaaggtgcca taactattgt aaggaatttt ggtggtgact
    67201 ttgttgaata ataagattat taaaagtaaa aaagcattat ataaaggagt gctagattta
    67261 accataatag ataaagttag agtgggagaa tcaaatgtaa ataaagaaaa tgattgtaga
    67321 tttagggatg aggtaataaa agaagctata gaatctgctg agataaaaaa gaatgagata
    67381 ttagaagaag caaaaatgaa tgcacaaaat atagaaaagc aagcatatga aaaagggtat
    67441 agtcaaggtc aaaaaaatgg atatgaagat ggatataaag agtcatataa tgaatatacc
    67501 caaaaagcta aagatgaagc agattttata aaaaatcagg cagacttaat actattacaa
    67561 gctaatgaga agatgactga gtacataaaa gaaaaaaata aagagattgt aagacttgct
    67621 attaatatgg ctagttctgt tctaaaaaag catttcgaag atgaagaatc tatgagtgat
    67681 ttgttaaagc aaattattca agattatgaa ggaagtagtt catttatagt aagatgtaat
    67741 tctttctata aagataatat agagaaagag tttgaattat tcaaagaaga aacatcacta
    67801 aaatcaagtg tatttgttat tgcagatgat agtatagata aaggcaatgc tatcatccaa
    67861 aaggaaaatg gaagaataat agttggtatc gattgtgcta tggaaaaact aaaagaagaa
    67921 ttgcttggtg aataaagtat gtataaaact gatatatcta tagattttga caaaataaat
    67981 aagaaaatag aaaatttaga actcactata tcagaaggta gagtcaaaaa gataatagga
    68041 cttactgtag aagttgaagg aataaaagct tttgttggag agttatgtgt tatatacaat
    68101 caagtcaata aaccagtgaa ttgtgaagta gtgggtttta aagataaaga agtcatatta
    68161 atggcgttgg gagagttaac attgatagct cctggttgta aagttatttc taaggggata
    68221 cctttaagtg ttatgtgtag cgataattta ctaggcaaag tacttgatgg tcttggaaat
    68281 cctatagata actcagatgc tgttttagga gatagataca acttgaacaa tgaacctcct
    68341 gatccaatga agagaaaaaa gatacgaaat ataatggaaa caggtgtaag agcaatagat
    68401 gcatttacta cttgtggtga aggacagaga atagggatat ttgcaggaag tggagtaggt
    68461 aaaagtacga ctctaggtat gattgctagg aatgcaaaag cagatgtaaa tgtaattgcc
    68521 cttattggag aaagaggaag agaagtatta gattttattg ataaagattt aggtgaagag
    68581 ggaatgaaaa aatctgttgt tgtatatgca acatcagata aagctccttt ggttaggcta
    68641 aaaggtgctc ttactgctac tgcaatagca gagtatttta gagaccaggg caaaaaagta
    68701 atacttatga tggactcggt aactagattt gctatggcac aaagagaagt tggtgtagca
    68761 ataggagagc caccagctca aaaaggatat acaccatctg tgtttgctat tttaccaaaa
    68821 cttatggaga gaacagggac atcagataaa ggttctataa ctgcatttta tacagtatta
    68881 gttgatggag atgactttaa tgagccaata gcagatacaa caagagggat acttgatggt
    68941 catatagttt tatctagaga cttggcaaat aagaatcatt atccttctat agatgtattg
    69001 aacagtttaa gcagacttat gaatgagatt gcttcaaaag aagacataaa aatagcatct
    69061 tttgcgagag atatgcttgc tgagtataga gaagcagaag atttgataaa tataggtgca
    69121 tatgcttcag gtacaaacaa aaaaatagat gaagcaatct actatcatga gcatattatt
    69181 aattttttaa aacaaggaat aaatgaaaag agctctttta atgaaactat aagtagttta
    69241 agaggaatct ttgaataaac aatttaaaaa aatatttgaa taggttgtga tggaattgga
    69301 taaaaatttt aagtttagat tacagaaagt tttagactta aaaataaaag atgaagaaga
    69361 gataaaaatg gaatttgcta agattcaaca aaaaaaaata gatatagaaa ctaatttaga
    69421 aaacttagaa agtaattaca gcaaatattc tataggtaaa aataatgata gtgttcaaaa
    69481 tcaaaaaata actattaact atttgctagc tttaaacaac tctataatgg atttatcaga
    69541 aaaactggat aagtcgacaa atgaacttga aaaagctaga aaacagctta taagcaaaca
    69601 gatagagaga aagtcattag aaaaattaaa agaaaaaaaa tatggacagt attataaaga
    69661 agaacagtta aaagaacaaa gcactaatga tgagtttgca agcatgagtt atttgagaaa
    69721 tagacaagtt ctataaaata gtaggaagtg aggatattat tgtatgaaga tacaagcaga
    69781 ttcttataat attattaaag atattgggaa tagaaaaaac tcatctaaga ataaaaatat
    69841 aaaaaatgat aaatttgaag ataatctata taagacaaca gaccataaaa aggttaaaga
    69901 tagaagagaa acaagtaagc aaaatgttag ctcagataga ccggaaaata gtgataatga
    69961 gtgtcattta gatgaagata aaagtaatca cttagaagat gaaaatacat atgaaaaaga
    70021 ttgtagtaat aataatgaag ctttgcagca attactgaat cttttaaaag agaattataa
    70081 aaaagataaa gatataaaca ctatattgaa taatataaaa aaactaagta tatcagatga
    70141 attaaaacaa gaacttaagc ttaataaaaa tatattaaat aagattgcaa atcaaaattc
    70201 agagctaaat aaagctaata taaataactc taatgatata gaaaatttag acatagttaa
    70261 attaagagaa cttttggagg ataatgctaa taaagatatt gaagtaatta ctaaaactac
    70321 agaaaatgat actaaaaata tagatttgta tagttttgat agcaatagaa tggataatct
    70381 taactcaaat aaacagaaag atgatagctc tgatattttg gaaaaactag caggggtaaa
    70441 tggaaataag agtgggaatt ttggacaagt aataaataaa aatgttgata tgaataaaat
    70501 taaaaatgat aatgtcaatt taaaacagat agaatcaaat gtaatggatg actctataaa
    70561 agctattaag catatgaaaa caaatgatat acaagaattg acaattaaat taagaccaaa
    70621 agaattagga gatatgaata tacaattgtt aaaagatggt gaaagtatga gagctgttgt
    70681 gactgttttc aataaagatg tctttgactc tataaataaa aacatagcag atttaaagca
    70741 acatcttgaa cttactaatg taaatataaa agatgtatca gtgcaaatgc acagcgataa
    70801 tacaaataca tctgatacct ttgataaagc atttgaacaa cagaatagac aaaataacca
    70861 agaaaacatg agtaagaaga atacaaatga taagcataat aatgtagtca tagaagatga
    70921 cattaaagaa aatactattg atgatgatag agtagattta ctagcttagt aagggggaag
    70981 tattgcatgt acggaatagc aacggctttg gcaggaactc agggaaacta taggtcaaat
    71041 aacttaagcc aacttgaaag aaatattaat gatattgcca ataaacaagt tagaagcaaa
    71101 ggaaatcaga cagtaacaga caatgggact ccaattatag gacaaggtga tgatgctgat
    71161 aaagacttgt ttatgaagat acttgtggca cagatgggta atcaagaccc aatgaatccg
    71221 caagacccaa cagaatatgt gtcacaatta gcacagtttg caactttaga aaagatgtca
    71281 gctatgaatg agaagctaga tgtactttta gccttaagta attccactct aataaactct
    71341 gctttaagta tggcaacatc attaattggt aaagaagtag aagtatctgg ggaagagaaa
    71401 gaagatgaaa acattgtagg agtagtaaag tccacatata taaaagatgg ggaagtacac
    71461 ttagaattag aagtagatgg aagtgacaaa actgtaggtg ttaaatatga aaaattactt
    71521 aaaataggag aggtagatga aaattcagga gaagaaaatg attcttcaga acacgaatct
    71581 ccagaagaag cataatatta aatgagaaaa gaggtaaatt catgataaaa gcaatgtatt
    71641 caggtgtaag tggaatgaaa gcaaatcaaa caaaattaga tgtaataggt aacaatgtag
    71701 ccaacgctgg aactacttct tttaagaaaa gttcagctag aataacagat tcattttatc
    71761 aaactgtact atatgcaagt gctccaacag ctgcattagg aggaacaaac ttaggacaag
    71821 taggtgtagg tagtaagata tcaagtataa ataaagatat ggtacaagga aatgtacaac
    71881 caactaatag accatctgat ttaatgatag atggagatgg atatcttcca gtagtaagac
    71941 aaggaacagt tatgtatacg agagatggtt cttttaattt agatacagga tttaaagcag
    72001 ctgatggtgc tttgaagaat attaaaggtg gaagacttgt aaatggtgat ggatatatgt
    72061 tacaaggtat gatttatgat ggggaatata aagctgatac tggagaattt gttaaaaagg
    72121 gtgatgctaa aggaaaagag cctattgtaa taccacttca aagtataagt cctaaggatg
    72181 gaacagttca aaatgtacta gagtataata tatcaaagga tggaacagta gaatttttat
    72241 tgagtgatgg tcaaagaact caatttgtct atgatatacc tgatggtgct aaggtaggag
    72301 atacacctgc tggaatagat aaattaaaag gtacaataca aaaagtgcaa acatatgcat
    72361 tccaaaatcc agcaggacta gatgcagaag gaggaaactt gtttaaacca tcagcaaact
    72421 caggagaccc acaaatagca ggagctacag gcacaataat acaaggggca atagaagctt
    72481 ccaatgtaga tatagcagaa gaatttacag aaatgataat agcaagtagg tctttccaag
    72541 caaacagtaa aataatatcg acatcagacg agatacttca agaaataata aatcttaaga
    72601 gatagtaggt acatattatg ataagagtaa cggatttaaa cggaagaaaa tacatattaa
    72661 attcagacct tatagtgagg attgattctg taccagaaag taggattctc cttacaacag
    72721 gagaaaaaaa ccttgtaaaa gagtcggtag atgagatagt agataaagta ataaagtata
    72781 aaagaaaaat aaatgtaggt tatattagga gcgaaaaata atgaaaaaaa cagattcact
    72841 gacatttatt ggactaatag tatctacagt attagtttta gttggtgccg caaaaggaag
    72901 tagttcaggg ttaaagaatt tttttgatgt ttcatcaata ttaatcacag tgcttggttc
    72961 atttggagct ctaatgatta catttactat agatgatata aaacttataa aaaatgcatt
    73021 acaatactca tttaagacaa tgagtgtatc aaagttagat ttactagaac aatttaaaac
    73081 actttctaaa aaagctagaa aagaaggtct tttatcaata gagagtgatg taatgggaat
    73141 agaagatcca tttatgaaga aagggttaga gctgtgtatt gatggattgg aaatcaatga
    73201 gataaggtcc atcttagaac tagagataga ttctgttgaa gatacaaata acagatactc
    73261 taaactattt aaaacttggg gaacctttgc acctgctttt gggatgttgg gaacactaat
    73321 aggtttaata caaatgttag ctgaccttac atctccagat ttaatagcat ctggcatggg
    73381 aaaggcatta attacaacgt tttatggttc tttacttgcc aatatcgctt tgaacccaat
    73441 tgcatataat atagatgaga agactgaaaa agaaatttat gtaaaggaaa tgatgttgga
    73501 aggtataata agcatacaat ctggggagag cagtatagta gttgaggaac gtttagccac
    73561 atacctttca aacaatgaga agttagaaat tatgaaatcc aataaaaata cagaaagagc
    73621 aatgagcaat ggcgcgtaaa aaaaataaga aaaaggatga gataaatcca gatgcatggc
    73681 tggctactta tgcagatact ataacactga ttcttacatt tttcgtatta ttgtatgcaa
    73741 catcagttgt agatatggaa aaatttaaaa acatagcaga tgcgttaaaa ggtcagtttt
    73801 ctgggacaag tatatttagt acgggttcaa gtacaagtga gaaatctcca atagacagtg
    73861 ttttagtgga taaaaatgat aaatcaaatt tagaacagga tttaaaagat aaagttaata
    73921 attctaactt acaaaatagt gtaacagtca aagatgatag tagagggatt ttactagagt
    73981 tagatgattc aattttattt gactctggga tttctgagtt aaaagtagat agtaaagcta
    74041 ctcttaataa agtatatgac atgataaaga tgatgaaaaa taagatagtt atagaaggcc
    74101 atactgataa tgtacctgta aaatcaagta cacatgaatc caattgggat ttatcttcta
    74161 gtagagcagt aagtgttgta agatactttg tagaagaaaa gggcatggac cctagactat
    74221 tttcggcaac aggatgtgga gagtatcaac ctttggtttc aaatgaaaca gcaaagggaa
    74281 gggctgagaa tagaagagtt aatatactta taactattga ctaggaggaa gaggtttgtt
    74341 caaaaataaa aaaattatta taattatttt gatactgatt attttctcag cgggagcagg
    74401 tttttttata ttaggagaag gtggaaataa acaagttgac aagattgcag gtttgtttat
    74461 tccaacagga aaaggtaaag atgaagtaaa gaccgaaaat cttgacttag aagagatggt
    74521 attaaagtta gctgatgaag gtgtaagata tttaaaagta tcaataactg tatcttatga
    74581 ttcttcatat aaagatatag aaaaaaatac gcctttaatt agggataata ttataaattg
    74641 ttttatggca aaaagggcag atgattttac tgctgataat ttaaagaaca taaaagaaga
    74701 aattaaaaat acattaaata tacaactagg tgaaaatgta attcaaaata tatatttcac
    74761 aaatatagta gtgcaataaa aggatggtaa gacatgatac tttatttact aaaaatatta
    74821 atatgtatcc caataatttt aatattgata gtcttatctt taaaaattag ccaaggaact
    74881 ttattaaaaa aatataatga taaatatgta aaaatactag atattgtaaa tataagtaaa
    74941 aacaatagca taataatttt aaaaataggt gaagaaggat gcattatggc atcttcttct
    75001 tctagcatga gtaaaataaa agatttgacc aaagaagaag tattaaaaat agaaaacgac
    75061 attaaagaaa gaaattttaa aattcaagat tttaaaatgg aaagaattaa aaagaaatat
    75121 gatttcagta gatatattgg aaaatttaca aaaaaggaag ataagtaaat ggaactatta
    75181 tcaaaattac ctttggctga tgtaccatat acaagttcaa tgcaattgtt tttatttcta
    75241 actgcattaa tgtttttacc atttgtaatg ttcatgatga caagctttgt cagaatagtt
    75301 ataagtttat catttttgaa atcagcatta ggagcacagc aagcaattcc aagtcaaatt
    75361 ttggtaggac ttgcaatagt attgacaata tttataatga gaccagtatt aaatgagata
    75421 aacgaaaagg cattacaacc atatatgaaa gaagaagtta ctatggaaga agctatgaag
    75481 gaagcagaag gacctattaa agagttttta ttaacacaaa ccagacagac agatttagat
    75541 ttatttgtag aacaggctgg tttaaaagaa aagaaattaa ctcgtgaaaa tataccacta
    75601 tctgttgtag ttccagcatt tgctataagc gaactaaaaa ctgcttttca aataggtttt
    75661 ttaatatata taccattttt gataatagac cttgttgtgg caagtgtttt gatgtctatg
    75721 ggtatgttta tgttgcctcc agtcatgata tcattaccat ttaagttatt attatttgta
    75781 atggtggatg gatggaactt gatagtaaaa acattgatat tgggatttgg ataggagaaa
    75841 aatagtatga gtgaatttat gataatgagt gttcttaaaa atggcatgtt tacaggagct
    75901 atgattgcag ctccagtact cattgtttct cttgtagttg ggcttttaat aagtgtgttt
    75961 caagctacaa ctcaaatcca ggagcaaaca ttgacttttg taccaaaact aatagctatt
    76021 cttttagtag tagctatcgg tggaagctgg atgttacata ctcttattag ttttacttct
    76081 gagatattca atatgatatc tcttataact aaataagtag gatacatatg atttttgtat
    76141 ttattagaat agtagcattc tttggaacac taagaatact atttccagct ggtacacctg
    76201 ctttatttaa gtcactcttt gcaatcatta tatcaatatt gatttcaagt actatgcaaa
    76261 ttgaatatgc aacaaatata gacaacattg tattgtttac cttatatagt gtaaatgaga
    76321 ccataactgg gattatgctt ggatatataa ccaacctatg tttttatagt atcagaatgg
    76381 cgggttctat gatggaccaa cagatgggat tatcaatgat taatatgttt gacccaaatt
    76441 caatgactca gacaacttta attgataatc ttatgaactg gacagcactt atgatatttt
    76501 ttaacatgga tggtcatcat gttttaatta gaggtataag gtatagtttt gagttaattc
    76561 caataggaaa accatttgta gataataaca tagattatat aataaacata tttgtgcagt
    76621 gctttttaac tggattcaaa atagcaatac ctattgtact ttgtctgctt atggcagatt
    76681 ttattttagg gcttatatca agaagtgtac ctcaattaaa tgtaatgata gttggtatgc
    76741 cattaaaaat attggttggt attgcattat ttatcatatc aataccttta attgtcaatc
    76801 aaataagtca tttattaagt caaataccaa agatgtatga gggaactttt gcactagctc
    76861 ctatgttttt tatgggttca gcagataaaa cagaagaagc tactccaaag aaaaagggag
    76921 aacaaagaaa gaaaggtaat atagcaaaga gtagagaatt acccgttgca atgactctac
    76981 ttgcattcac cttattagta cctacattat tttcatatgt agtagataca cttaaatctt
    77041 cgcttaatta ttttttgagt ctagattttt atatgaacat aaattattca aacctagaga
    77101 aattagttat agcaggatta atggattttt ttaagatatt tttaccaata gctattccct
    77161 ttttagtttt aggcataata gcaaacctat ttcaggtggg aatactgttt actggtgaaa
    77221 ctttaaaacc aaatttatca aaattaaatc caattagtgg attcaaaaac atgttttcta
    77281 tgagaagttt gtcaacctta ataaaggata cagcgattat atctattttg gcttacatag
    77341 gatatacatt cttccaagat aattatttag atatattaaa gttaggtaac atatacctac
    77401 caactttaat gtacacagtt aaagacttag tatattcaat attgagtaag atttgtgtag
    77461 ctatgatagc tatagcagtt gcagattatg tttatcaaag atacagtcat aaaaagcaac
    77521 tgagaatgac aaaacaagaa gttaaagatg aatataaaaa ctcagaagga gacccagaag
    77581 taaaagctaa gataaaacaa aaacaaagac aaatttcgtc tcaaaggaca atgcaagcag
    77641 taccaagtgc tactgtaata gtaaccaatc caacccactt atctatagca gtgagatatg
    77701 aaaaagggaa agaccaagct ccagtagtgg tggcaaaagg tgcagattat ttagctttta
    77761 aaataaggga aattgcaaag ggaaatgaca tacctataat agaaaataaa cctattgcta
    77821 ggttgttata taagcaagta gaaatagacc aagaaattcc agaggacatg tatcaagctt
    77881 ttgcagagat attagtagca gtatataaaa tcaaaaatag atacaaagtc cccaaaaggt
    77941 aggataagta atgaataagt ttaatttaaa ggaaaatatg gacgtaatag tggcatttgg
    78001 tgttgtaggg attgttctta tgatgatagt gccgttacct acatttatat tagatatttt
    78061 actggcaatt aacataagtt tatctgtgct aattttacta atgacactat ttacaacaaa
    78121 tgtacttgat ttatctatat ttccaacagt gttacttgtg acaacactat ttagattggg
    78181 attaaatctt tcatcaacta gattgatttt aacacaggga tatgcaggtg aagttataga
    78241 ggcatttgga agttttgttg taggtggaaa ttacgtagta ggaataatta tattcttaat
    78301 tatattaatt gttcaatttg ttgttataac caatggttct ggaagagtat ctgaagtaac
    78361 agctagattt acgttagatg ccatgccagg taagcagatg agtatagatg cagatttaaa
    78421 tgcaggagtt atagatgaca aaactgctag aaaaagaaga aaagagcttc agcaagaagc
    78481 agatttttat ggctctatgg atggagcaaa taagtttgta aagggagatg ccatagcagg
    78541 tcttatagta acagcaataa acataatagg tggaattgta ataggagctg taatgctgaa
    78601 tatgactctt atgggtgcag cacagacata tgtaagactt actatagggg atggtcttgt
    78661 aagccagata cctgctctat taatatctac atcagcaggt ataatcgtaa caagagcttc
    78721 tactgatgaa aactttggtg gattagtagg taaacagtta acagcaatac caaaagcagt
    78781 aatgatgact ggctgtgttc taatcgtact tggtatgatg cctggattac ctaaaccagc
    78841 atttttttca ctaggtatag gtgctatagc agcaggttac tttttaggaa gagaaaagaa
    78901 agatacttta gaagacttgg agtttgaaaa acctgatatg gtaaatccag ataaaaatga
    78961 agtagaagat gtaacaaact taataaatgt agaatcaata gaagtagaaa ttggatatgg
    79021 tttaatatct ttagctgatg aatcagcagg aggagattta cttcagagaa tagcatcaat
    79081 aagaagacaa tgtgcaatag acatgggtat agtcgtacaa cctataagaa taagagataa
    79141 tttacagtta aatccaaacc aatacaatat aaaaataaaa gggaatgtag ttggtgggta
    79201 tgagataatg cctaatatgg ttttatgtat ggatcctatg aatcaaggat ttagtatatt
    79261 tggaataaag acaattgagc ctacttttgg aatagaggca ctttggatag aaagtgacaa
    79321 ggtagaagat gcagagctaa agggttatac agttgtagat tcatccacaa tacttataac
    79381 tcacttacta gatataataa aatcaaatgc acacgaatta ctgggaagac aagaagttaa
    79441 gactattata gatgcagcaa gagaaaatta tagtgctgta gtagatgaat tgataccaga
    79501 tttaatgaca cttggtgaaa ttcaaaaagt acttaaaaat ctgttaagag aaaaagtaaa
    79561 tataaaggat agagttacaa tacttgagac acttgcagac cagtctagaa atacaaaaga
    79621 tatagagctt cttactgaat atgtaagaat agctttggct agaagtattt gtaataattt
    79681 agttgatgaa gataaggcaa ttgtagtggc tacattgtct ccagaaactg aagaattggt
    79741 atctaataat ttacaaaggt ctgtaaatgg aacttatcca gcagttgacc cagaaaatac
    79801 aaataaaata tttgagagta tacaagaagt aatgaacaat gtatatttca atcataatat
    79861 accagtaata gtagtatcac caaagataag agctccattt agaaaattag ttgaaattgt
    79921 atatcctaat ttgactgtat tatcattaaa tgaaatacct aacgatatta aaatcaaagc
    79981 agaaggtgtg gtgagcatat atgatgacga aaaagtatac agctaacaca attcaagatg
    80041 ctatgaatct agccaaaatg gaattgggtg acaatattac attaatagat aaaaaagagg
    80101 taagaaaatc tggaataaga ggcatttttt caaagaaaga tattgaattg actattggat
    80161 gggaaaagaa agataattta gaacaaaaag atttaaaacg agagatagaa caactaaagt
    80221 caattataaa taatatgggg tttgataata aaaatgataa tgatatagat aaaatatgca
    80281 agaatttact aaacttagat ttaaatcaag aaattgtaga atttataaaa gctgatttac
    80341 aagaaatgaa gttcaatgga attgatacaa gtaaaaattt agtagaaagt ctaaagaaaa
    80401 agattaaaat agaaaatcaa gcaataaatg gtaaaattgc tttagttgga ccaccaggag
    80461 taggtaaaac gactacaata gcaaagttgg ctgccaaatt agtttttgag gaaaataaaa
    80521 aagtaggagt aataactata gatacataca ggattggtgc tgtagaacag ttaaagatat
    80581 atactgatat aatgaatatt ccttttaaag gggtaataag ccctgatgag atggaattgg
    80641 cacttgatgc gatgaaagat tgtgatgttg tattaataga tacaacaggt agaggctata
    80701 aaaactctat gcaaatatta gaaatcaaaa atcttataga taaagctgaa actgataata
    80761 tacatttagt tttgaactgt acaacaagag aaagtgatac aaaagcaatt atagattcat
    80821 atagaaatgt gaattttaaa agcttaataa ttacaaagtt agatgaaaca ataacatatg
    80881 gctcaatatt taacataatg aattatgcac aaaaaccaat atcatatatt acaacaggac
    80941 aaaatgttcc tgatgatatt ataaaaccta atgaagataa gattataaga ttactattag
    81001 gagttgaaag tatatgatag accaagctca aattttgaga aaaatggcaa tggaaaaaag
    81061 aggttctgat gagattatag tagagaatga gaatatgcct aagataatta caatagcttc
    81121 tggtaaaggc ggcgttggaa agagtaatct cgctacaaat ttgtctatat gcttaaccaa
    81181 acttgataaa aaagttctta tattagatgc agatatagga atgtctaata tagatataat
    81241 aatgggggta aatgtaaaag ggactataat tgatgtaatt aatggcgaaa aaaatataga
    81301 agatataatt tcacagacta agtatggtgt aaatgtaata tctggaggtt ctgcccttaa
    81361 tcatatagaa gactttacag aagctcaaag aaataagttt atacatagca tagaacagat
    81421 tcacaatgtg gattttataa taattgatac aggagctggt atgagcaaaa gcctattgtc
    81481 atttatatac tgtagtactg aatttttctt aataacaact ccagaaccga catcattgac
    81541 tgacgcatat agtttattaa aagctataag taattttggc ataaagaaaa gtgcaaatat
    81601 aataatcaat agggtaattg atttagaaga agcgaaatct acatacaaaa gaataaaaat
    81661 ggttgtggac aaatttctaa accttaatct ggaattgtat ggatatataa tagatgacaa
    81721 aaaagtaagt ttatgtgtaa aaaaacagat accattcatt ttagaatatc ctacaagtat
    81781 tgcatcaaaa tgtattatag ccatagcaaa gagaatggta agtcagtcaa gagaagatat
    81841 tgttgataat aaaagttttc taagaaagat gtttagtata tttaaaagct aaggaggcgt
    81901 agttaatgaa tagagaagaa ttaataaaag agaatatgcc tcttgtaaag agtatagcaa
    81961 gaaaattttt tataccaggg aaaggttttg aatatcaaga cttagtaaat agtggagtca
    82021 ttggattgat tgatgcaata aataaatttg atgctgaaaa aggggcaaag ttttctagtt
    82081 actcttatat aaaaataaaa tctgctatat tagatgaaat tagaaatcaa agtccaattt
    82141 ctaaacataa tctaactaaa gtaaataagt ataatagagt ggtagaaaag ttgcaatcta
    82201 aattattaag agagccaact tcatatgaaa ttgcaaaaga attaaaggtt tcagaaaaag
    82261 aacttcatga tatcgaaagt aatatagata tgttaaatat tgtatcatta aactatgtaa
    82321 tctttgaaga tacaaatgaa actgtacaag atgtaataag tgatagagaa gaggaagctc
    82381 cagaaaatat aatagaagaa gaagaaaagt tagagattct atccaaagca attagtaatt
    82441 taaatgaaag agaaaaatta atactttcac tgtactatta tgaagattta aatctaaagg
    82501 agatagggaa agtgctaggt gtttcagaat caagagtttc acaactccac agaaaatcaa
    82561 taagaaactt aagaaacaag ataaaagaac ttaaatattc tatatagatg gtgattgata
    82621 agatgataca aattatatta atagtagtgt ctattttaat aatagtaact atagttataa
    82681 atttacataa ggaatcaaaa aataaagata acagatactt tgataaaata tttgagcaag
    82741 aatatgaagc aaatgataga ttaataattg cagaaaaaag aagattcttt ttagacaaag
    82801 tacttgctga aataagaagt aataatcata taaaagttta tgaaaattat aacctaataa
    82861 aggctaatga agaaagaaag gaaaacatat ttatagaatc aaaaaaggaa gtaagacaag
    82921 aaaatgagtt atctcttaaa gtgaaacatc ttataagttc aggttatgat gatgtggaaa
    82981 tatgtaagat gctagatatt ggaaaggggg aactgtcatt aataaggagt tgttacaaaa
    83041 tataaggata ttattatgtg ataaaaaagt attcttagga ataggtattg gtatattaat
    83101 atcaacttta tgtataatgc tttttagtaa taatgatatg agtaaggcag agatagaaaa
    83161 aaaggccaga gcgttaggca tgaaatatac aagtgagatg aaagtcttag aatagatgat
    83221 actgtttaga catttacaaa aaaggaggtc ataatgtgat aagaggatta tatacagcag
    83281 tttctgctat gataactaat caacaaaagc aaaatgttgt tgtcaataac ctagctaata
    83341 tggatacaaa tggatataaa agtaaacaac ttttgactaa aagttttgat gaattaaagt
    83401 tggaaggtta caataactac gcaaatggaa ctaaacaaaa gcagattata ggcgatataa
    83461 gtccaggtat ttctatggat gaaactatca caaattttaa tcaaggacct ataaaaacta
    83521 ctgataataa aatggatgta gctattcaag gtaagggatt ttttctagtt agtgatgcag
    83581 ctggaaatca attttacact agaaatggga acttcagaac agacaatcaa ggtgacctta
    83641 taacaagtga agggtattat gtacttggga cgaatactgc tactggtgct gtaggtcata
    83701 taaatgtagg aaatcaaaaa tttgaagtgg caaaagataa tacaatatca ctagacggaa
    83761 atgctatgta taaatttaat attgtagatt ttaataacta caataactta aaaaaagaag
    83821 gagataactt atattctgga ggaggagcta tgaaagtaaa taatgcactt acaatacaaa
    83881 gtgcgataga gtcctctaat gtagatatgg tatctgaaat taataatatg atgacaatat
    83941 caagagaata tgaggcaaat caaaagataa ttcaggctat ggattctaaa ttagcaaaaa
    84001 tagcaagtga gattggttca gtaagatagg taataggagg tgaattttta tgtacacaat
    84061 gttttatact agtaaaacag ctttatcagc aaatcaaagt aaactagata taatatctaa
    84121 caatatagca aattctgatt caacaggata taaaaaaata aatatggaat attctgattt
    84181 agtggatgaa gtactaaata gaccatcata ccctacaaat ggtaaagata tatcgactgg
    84241 aacaggagct aaggcaacag ctcccatgag aaattatgaa caaggtgcat tggctcctac
    84301 agatagtaag agtaatttgg cgatagatgg agaaggattc tttagagtga taagaaaaga
    84361 tggtacatat gcatatacaa gaaatggtgg atttaatgta gatgctttag gtaagattgt
    84421 agatgataat ggaaatatat tagatgtcca atttgatgca ggatataact ataataatac
    84481 aaatatagat agtacaaacc tgacagtttc aagaaatgga gagctattcg tagataataa
    84541 aaaaatagga aaaatcaact tatatcaacc tataggaact caaaatttta tatctgaagg
    84601 agatagttta ttcgtcgcaa ctgatgcagc acagattaaa caagttgaga aagtcgatat
    84661 agttcaaggc tatagagaga ggtcaaatgt ttctttacaa gaagaatttg ttgacttaat
    84721 agccactcaa agagcatttc aaatgaactc aaagggaata aagacagcag atgaaatgtg
    84781 gcaaatagcg aataatttaa gagctaaata attatgtaag gtgaggaata ttcatgaatg
    84841 atatgaaaga gtacgatttt ggcaaacctc agagttattc aagagaaaat ttaacttgtt
    84901 taaatttttt attagctgaa ttttgtaaaa aatataaaaa ctatataatt tatgaactta
    84961 agtgtaattc tagtatggtt gttgatagta tagaccaagt aaattatcag acttttttag
    85021 atagagtaac ttcttcgtgc gtagtagtac aaaatgcaat ggaacctgtt atgaaaaact
    85081 tttcttttag aatagataga agtgtagctg atatgtggat tgatataact tctggaggaa
    85141 ctggagttgt aaaggataat gatagagagc ttacagaact tgataaaaaa gtgcttttac
    85201 accttatgga tgatttagta agaaatatgc acttatttga gggttttgaa aatatacaag
    85261 tattggatac acatacacat attaatttac cacaattatg ttctccaact gcaccagtat
    85321 gcgttgtaga tttaaaagtg ctaaatgata atgagtatat tggaagtgtt tctctttgtt
    85381 ttccatacaa tggtttagaa gctctgttag aaagtatatc tgttatagaa ttttttgata
    85441 atgatatagg agatgattca gaggaattta ccaaaaaaat atataatagt gtatctaata
    85501 tagaattatc ggttattgca gagataggaa aagtatcaat taatgttgaa gacttactta
    85561 aactagaagt tggagatgta atagtaacaa ataaaaaaat aaatgattat atagatatat
    85621 ttgtagaaaa ttcaaaatca tatacagcaa caccaggatt tatatcaagt aaaaaaggtg
    85681 taaaaataaa tgatgctgtt ggaaaagagg tgtagttatg gacaatagta atcttatttc
    85741 agatgaagaa gcaaagatgc tattaaatga taaagttgaa agtgaagttg atggagatga
    85801 tgagttagcc ttagatgtgt ctgaagttaa tcgaaataat atacaaagga tacttgacct
    85861 taagttagaa ttatctgtgg ttataggaag aactaagatg actctaagag atattttaaa
    85921 cctacataaa ggttctctta ttgaactgga tactttagca gaccaagatg tggaaatact
    85981 aatagataat aaagtgttgg cttatggaaa agtagtggtg gtagatttaa attttggtgt
    86041 aaagataaca agtatagtaa gtgaagaaga tatggtaaaa tctcttgttt agagataaca
    86101 tcaattaata cttaaggcat gaggtggtac ttattttaaa cttaaatgat ataaaaaaag
    86161 atatattaaa actcaataaa aaagactcat gttctctata taatgaatct attaataata
    86221 taaataataa ttgtatatcg agtggattga aatttttaaa acaagcaaga gatttaaacc
    86281 cagatgatgt tgatatatta aatctcacag gtcttgtaaa tttactaaaa tgtaattttg
    86341 atgaggctgt agaaagtttc tataagagtt cactttgtga aaaaactgct ctgtgtgaaa
    86401 agtatataaa catgcttaca tctgaggagt ttttaatttt ctttgaaagg tacaatcaac
    86461 tcataaggtt aataaacaga ggaatgtata aagaagctat acaagggttt aaacttataa
    86521 ctgagcaata ctgtgattta atagaacctt atgaattgct tgccttactg tatgacaagg
    86581 aagaagaata tataaaattt gatgaatgtt tagaagtatt gaagattatt gataaggaaa
    86641 attatttatt aaatcaagaa aataacacat tagatatgta taatagtgct aatatacaaa
    86701 ctaaaagtaa tataaaagta gatgattata agaatgagtt cttacataaa agtagtagta
    86761 accataaaat taatgattat aatgatgtaa ctaaagaaaa gagttcaagc aaaaaccaga
    86821 aaagttcaga ttctaataag aaaaaaagta ttaaaaaaaa taaataccta tatatagcca
    86881 taatattagg aatattatta gtaggacaaa gtatatatag ttcttataag atgaataatt
    86941 taactgataa aatatctaaa aataatgaaa ccaaaaatga agagtcaata gattctaact
    87001 tgactaagaa agaaaataat atagaagaaa atgaagatat gagtaaggct tctaatataa
    87061 ataagagtaa taaaaacatt aataaagagg atgatgtaaa atctaaaaaa aatactgtag
    87121 aaaatgaaga tgataaagat tctgacttat ttacagagga tgaattgatg tctaaggcga
    87181 atactttaaa atcagaaaag aaaactaaat cttctataca actatataag aaagttgcag
    87241 atataggtga aaataaaggg aatacatctg aagcaactta tcaagttgct attctaagtg
    87301 aaaagttaaa agactataaa actgctgaag aatattataa aatgtatgta gaaaattact
    87361 cagaaaaaga tgcttatttt gatgaatctt attataattt aggtatgatg tactataaca
    87421 atggtgattt aaaaaattct aaattgacat taaagaagtt ggttaataag gtaccaaata
    87481 gtatgtataa taattcaaaa gtaaaagaaa ttttaaaaga agaatagtta aattagataa
    87541 gaaaaataaa ttattttatt tt
//
LOCUS       DAEOTL010000007        83878 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEOTL010000007 DAEOTL010000000
VERSION     DAEOTL010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 83878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83878
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.007"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(120..1721)
                     /locus_tag="KRH82_000715"
     CDS             complement(120..1721)
                     /locus_tag="KRH82_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBG8654010.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDDILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1832..2509)
                     /locus_tag="KRH82_000716"
     CDS             complement(1832..2509)
                     /locus_tag="KRH82_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654011.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2522..3217)
                     /locus_tag="KRH82_000717"
     CDS             complement(2522..3217)
                     /locus_tag="KRH82_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBG8654012.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3269..4468)
                     /locus_tag="KRH82_000718"
     CDS             complement(3269..4468)
                     /locus_tag="KRH82_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBG8654013.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVEGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4729..6774)
                     /locus_tag="KRH82_000719"
     CDS             complement(4729..6774)
                     /locus_tag="KRH82_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654014.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFYNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQELEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7184..7993)
                     /locus_tag="KRH82_000720"
     CDS             complement(7184..7993)
                     /locus_tag="KRH82_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654015.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8077..8610)
                     /locus_tag="KRH82_000721"
     CDS             complement(8077..8610)
                     /locus_tag="KRH82_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBG8654016.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8760..10109)
                     /locus_tag="KRH82_000722"
     CDS             complement(8760..10109)
                     /locus_tag="KRH82_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBG8654017.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGADLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10121..11503)
                     /locus_tag="KRH82_000723"
     CDS             complement(10121..11503)
                     /locus_tag="KRH82_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBG8654018.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFVVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11747..12961
                     /locus_tag="KRH82_000724"
     CDS             11747..12961
                     /locus_tag="KRH82_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBG8654019.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13138..15051
                     /locus_tag="KRH82_000725"
     CDS             13138..15051
                     /locus_tag="KRH82_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654020.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGIFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15322..16296
                     /locus_tag="KRH82_000726"
     CDS             15322..16296
                     /locus_tag="KRH82_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBG8654021.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16317..16592
                     /locus_tag="KRH82_000727"
     CDS             16317..16592
                     /locus_tag="KRH82_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBG8654022.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16605..17768
                     /locus_tag="KRH82_000728"
     CDS             16605..17768
                     /locus_tag="KRH82_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBG8654023.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18106..20385
                     /locus_tag="KRH82_000729"
     CDS             18106..20385
                     /locus_tag="KRH82_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8654024.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20480..21820)
                     /locus_tag="KRH82_000730"
     CDS             complement(20480..21820)
                     /locus_tag="KRH82_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8654025.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFYLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(21832..22614)
                     /locus_tag="KRH82_000731"
     CDS             complement(21832..22614)
                     /locus_tag="KRH82_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654026.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22629..23651)
                     /locus_tag="KRH82_000732"
     CDS             complement(22629..23651)
                     /locus_tag="KRH82_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBG8654027.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGKGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23657..24670)
                     /locus_tag="KRH82_000733"
     CDS             complement(23657..24670)
                     /locus_tag="KRH82_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBG8654028.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24798..25736)
                     /locus_tag="KRH82_000734"
     CDS             complement(24798..25736)
                     /locus_tag="KRH82_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8654029.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAVPFFSQSYNPIGKELLLESVKNELTK"
     gene            26006..26470
                     /locus_tag="KRH82_000735"
     CDS             26006..26470
                     /locus_tag="KRH82_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654030.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26582..26899)
                     /locus_tag="KRH82_000736"
     CDS             complement(26582..26899)
                     /locus_tag="KRH82_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8654031.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(26912..27643)
                     /gene="chbG"
                     /locus_tag="KRH82_000737"
     CDS             complement(26912..27643)
                     /gene="chbG"
                     /locus_tag="KRH82_000737"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBG8654032.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKPVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27669..28979)
                     /locus_tag="KRH82_000738"
     CDS             complement(27669..28979)
                     /locus_tag="KRH82_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBG8654033.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCTNPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29056..30369)
                     /locus_tag="KRH82_000739"
     CDS             complement(29056..30369)
                     /locus_tag="KRH82_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8654034.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30391..30702)
                     /locus_tag="KRH82_000740"
     CDS             complement(30391..30702)
                     /locus_tag="KRH82_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654035.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(30902..31606)
                     /locus_tag="KRH82_000741"
     CDS             complement(30902..31606)
                     /locus_tag="KRH82_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654036.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31697..33058)
                     /locus_tag="KRH82_000742"
     CDS             complement(31697..33058)
                     /locus_tag="KRH82_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8654037.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33557..34711
                     /locus_tag="KRH82_000743"
     CDS             33557..34711
                     /locus_tag="KRH82_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8654038.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(34793..36511)
                     /locus_tag="KRH82_000744"
     CDS             complement(34793..36511)
                     /locus_tag="KRH82_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBG8654039.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLTSESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(36516..37505)
                     /locus_tag="KRH82_000745"
     CDS             complement(36516..37505)
                     /locus_tag="KRH82_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8654040.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(37601..38650)
                     /locus_tag="KRH82_000746"
     CDS             complement(37601..38650)
                     /locus_tag="KRH82_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8654041.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(38927..39595)
                     /locus_tag="KRH82_000747"
     CDS             complement(38927..39595)
                     /locus_tag="KRH82_000747"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBG8654042.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(39601..40974)
                     /locus_tag="KRH82_000748"
     CDS             complement(39601..40974)
                     /locus_tag="KRH82_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBG8654043.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(40971..42749)
                     /locus_tag="KRH82_000749"
     CDS             complement(40971..42749)
                     /locus_tag="KRH82_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBG8654044.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(42866..43189)
                     /locus_tag="KRH82_000750"
     CDS             complement(42866..43189)
                     /locus_tag="KRH82_000750"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBG8654045.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(43176..44153)
                     /locus_tag="KRH82_000751"
     CDS             complement(43176..44153)
                     /locus_tag="KRH82_000751"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBG8654046.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYFDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(44168..44731)
                     /locus_tag="KRH82_000752"
     CDS             complement(44168..44731)
                     /locus_tag="KRH82_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBG8654047.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(44783..45274)
                     /locus_tag="KRH82_000753"
     CDS             complement(44783..45274)
                     /locus_tag="KRH82_000753"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBG8654048.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(45277..47202)
                     /locus_tag="KRH82_000754"
     CDS             complement(45277..47202)
                     /locus_tag="KRH82_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBG8654049.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(47204..47515)
                     /locus_tag="KRH82_000755"
     CDS             complement(47204..47515)
                     /locus_tag="KRH82_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654050.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(48145..48420)
                     /locus_tag="KRH82_000756"
     CDS             complement(48145..48420)
                     /locus_tag="KRH82_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBG8654051.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(48535..49944)
                     /locus_tag="KRH82_000757"
     CDS             complement(48535..49944)
                     /locus_tag="KRH82_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBG8654052.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(50315..50977)
                     /locus_tag="KRH82_000758"
     CDS             complement(50315..50977)
                     /locus_tag="KRH82_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBG8654053.1"
                     /translation="MIDISIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(51231..53450)
                     /locus_tag="KRH82_000759"
     CDS             complement(51231..53450)
                     /locus_tag="KRH82_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8654054.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNNGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LYEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIKMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRTYGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(53726..56380)
                     /gene="adhE"
                     /locus_tag="KRH82_000760"
                     /gene_synonym="adhC"
     CDS             complement(53726..56380)
                     /gene="adhE"
                     /locus_tag="KRH82_000760"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBG8654055.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            56884..57084
                     /locus_tag="KRH82_000761"
     CDS             56884..57084
                     /locus_tag="KRH82_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654056.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(57291..57881)
                     /locus_tag="KRH82_000762"
     CDS             complement(57291..57881)
                     /locus_tag="KRH82_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBG8654057.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(57884..58759)
                     /gene="dpsA"
                     /locus_tag="KRH82_000763"
     CDS             complement(57884..58759)
                     /gene="dpsA"
                     /locus_tag="KRH82_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBG8654058.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYTLDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(58835..60226)
                     /locus_tag="KRH82_000764"
     CDS             complement(58835..60226)
                     /locus_tag="KRH82_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBG8654059.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENLLSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(60230..61366)
                     /locus_tag="KRH82_000765"
     CDS             complement(60230..61366)
                     /locus_tag="KRH82_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBG8654060.1"
                     /translation="MKEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEETKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(61398..61943)
                     /locus_tag="KRH82_000766"
     CDS             complement(61398..61943)
                     /locus_tag="KRH82_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBG8654061.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            62267..63046
                     /locus_tag="KRH82_000767"
     CDS             62267..63046
                     /locus_tag="KRH82_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654062.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            complement(63501..63929)
                     /locus_tag="KRH82_000768"
     CDS             complement(63501..63929)
                     /locus_tag="KRH82_000768"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBG8654063.1"
                     /translation="MIKKLNNKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   64118..64732
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=64184..64212
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(64916..65182)
                     /gene="cas2"
                     /locus_tag="KRH82_000769"
     CDS             complement(64916..65182)
                     /gene="cas2"
                     /locus_tag="KRH82_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBG8654064.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     gene            complement(65185..66165)
                     /gene="cas1b"
                     /locus_tag="KRH82_000770"
     CDS             complement(65185..66165)
                     /gene="cas1b"
                     /locus_tag="KRH82_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBG8654065.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIVDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            complement(66168..66719)
                     /gene="cas4"
                     /locus_tag="KRH82_000771"
                     /pseudo
     CDS             complement(66168..66719)
                     /gene="cas4"
                     /locus_tag="KRH82_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
     gene            complement(66734..69055)
                     /locus_tag="KRH82_000772"
     CDS             complement(66734..69055)
                     /locus_tag="KRH82_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBG8654066.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTERLSKVYLQSVEKRIDKNHKYYNLYIMLKGILHRLDHSASAHEVVECNNVIN
                     IGEQTENYLMKEFGSLREAQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIVGVGESNDTFLGLLHSTAIDYLEESNQENSSEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QSGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIHENKHTKQIFGKGVLISNEIDQFI"
     gene            complement(69066..69767)
                     /gene="cas5b"
                     /locus_tag="KRH82_000773"
     CDS             complement(69066..69767)
                     /gene="cas5b"
                     /locus_tag="KRH82_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBG8654067.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKVLN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            complement(69769..70683)
                     /gene="cas7i"
                     /locus_tag="KRH82_000774"
     CDS             complement(69769..70683)
                     /gene="cas7i"
                     /locus_tag="KRH82_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBG8654068.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRADGNMYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGDIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            complement(70685..72562)
                     /gene="cas8a1"
                     /locus_tag="KRH82_000775"
     CDS             complement(70685..72562)
                     /gene="cas8a1"
                     /locus_tag="KRH82_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBG8654069.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNLIKEKLDSMSKIKSYDEFDSLESLVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIAKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQEYVSSICDVCKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTSINELFERNNSLKAQKSESSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHLTNNILRNKVKNDMESNNKSNISGIDCFRVVQLRVLINSYKKG
                     VYKMDSKNLEKNDEKLKIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            complement(72568..73305)
                     /gene="cas6"
                     /locus_tag="KRH82_000776"
     CDS             complement(72568..73305)
                     /gene="cas6"
                     /locus_tag="KRH82_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBG8654070.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KAYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            complement(73383..74300)
                     /locus_tag="KRH82_000777"
     CDS             complement(73383..74300)
                     /locus_tag="KRH82_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBG8654071.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILSEIEKMKKIY"
     gene            complement(74579..76495)
                     /locus_tag="KRH82_000778"
     CDS             complement(74579..76495)
                     /locus_tag="KRH82_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654072.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKEDVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(76495..77241)
                     /locus_tag="KRH82_000779"
     CDS             complement(76495..77241)
                     /locus_tag="KRH82_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654073.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     YIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(77345..78196)
                     /locus_tag="KRH82_000780"
     CDS             complement(77345..78196)
                     /locus_tag="KRH82_000780"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBG8654074.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQV
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(78444..79448)
                     /locus_tag="KRH82_000781"
     CDS             complement(78444..79448)
                     /locus_tag="KRH82_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654075.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            complement(79458..80150)
                     /locus_tag="KRH82_000782"
     CDS             complement(79458..80150)
                     /locus_tag="KRH82_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654076.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(80464..81423)
                     /locus_tag="KRH82_000783"
     CDS             complement(80464..81423)
                     /locus_tag="KRH82_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8654077.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLIANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            complement(81456..82334)
                     /locus_tag="KRH82_000784"
     CDS             complement(81456..82334)
                     /locus_tag="KRH82_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654078.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKIKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(82327..83109)
                     /locus_tag="KRH82_000785"
     CDS             complement(82327..83109)
                     /locus_tag="KRH82_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654079.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(83110..83739)
                     /locus_tag="KRH82_000786"
     CDS             complement(83110..83739)
                     /locus_tag="KRH82_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654080.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTKNTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
BASE COUNT        27911 a        14463 c         9402 g        32102 t
ORIGIN      
        1 aataaatatt aatactataa ataaaaacga agcatgattt ttatttaaat aaatctcaaa
       61 cttcgtcttt acttacttag atatttattt actttctaaa tcctattatt tttaaaacct
      121 tatcttttca atacttcacc acatttattc tcagtaatct ctccattttc taacgcaatt
      181 tttccattta caattacata ttcaacacca ttggctagta attgtggctt tgaaaaatca
      241 atatcttctg acctaggata actatagtta tccatgtcaa taactgctat atcagctatc
      301 aacccttctt taagaatacc tctatttttt attttaaatt gcctagctgg taatgaagta
      361 actcttctta caatctcttc caatctaaca ccagactttc tgtacatatt gaagaaaatt
      421 ggaaaagctc ctcttctttg tagttcaaac catgacatat ccccacccac actaaacaaa
      481 caatctgaac caaccataac aaatggatta tcaattattt tatcatcatg tagtttatct
      541 gggaaatcag ctctatacat tcctcctaaa caaaagataa gttcttcgtc tccatctaaa
      601 agtaaatcga gtaataactt gtcttcatct attccttttt gtgtagctat ttcacgtatt
      661 gatttctttt ccatattaat atctttagtg tttagaagta ttatactccc cctatctcca
      721 agtataaatg cttcttttaa tataagtgtt cttccctctt catttctaag agcatccatt
      781 accccatcta tacctaattc aaatagacta gatgatattg ccataataaa ttgaattact
      841 ctttttttct tcatacaatg cccagaactt cttggtactg tgtcaaccat tatttcaaca
      901 ccattatacc tagcctttaa tatatcatca aatgcttcta tttcaactgg acttaagtga
      961 gatacttgaa ccctagcacc acttttttgc ccaacctcta tggcttcttt tactgcatta
     1021 tatcttccta tgtaatctct aatatgagat gtatatatac catcatactc tttaatctgc
     1081 cttgcaatat caacaagttc atcaatatca gcatacttac ttggtatata tgccaatcca
     1141 gtagatattc caaaagcacc acttttcatt ccatcattta ttatatctgt aatttcattt
     1201 ttttcctttt ctgtaggagg tctatcctta gaacctccca taacactcca tcttatagtc
     1261 ccatgcccca acaagaatcc catattaaca gaaataccac ttttagatat aaggtcacaa
     1321 tattctgtaa aattattcca acatttattt ttatctataa gatacttttt ttcttcttca
     1381 agtaatagac catttttata catatattca tacacatttt cagaagaata tggtgttata
     1441 gaatgtccac aattaccatt tatagttgtt gtaactcctt gttttagaaa cttttcaaat
     1501 ttaccatcta gtattgctac tatttcttca tgaacatgag ggtcaataaa tccaggtgtt
     1561 ataacttttc cacaacaatc aatctcttta tttgtattgc tatttatctt agaatctatt
     1621 tttgctatta agttgtcttt aattgctata tctccataaa aaccaggatt acctgtacca
     1681 tctattataa atccattttt taagattaaa tcatatatca aaatattccc tccttaaaaa
     1741 ccaattttta aataatctta atgtaatttt tatatttgaa aatcaaatta ttatatttca
     1801 tatttgaaaa ttcactatta tttcattgta attagtcact aagcttatct ttatacatag
     1861 ctcttgcaat taatatagta ccaaatacac atataagaac tactagagac tgtggtatta
     1921 taccttgctt tgataatata atagtcaata cagatattac aattgctact agacctaatt
     1981 ttttatcttg taaaaatact tgtccaaaaa ctgacccaaa tagagctggt aaaattaagt
     2041 ttaatttttc tactacttca gctggaattt tagataatac gcttcctcct aaaattaccc
     2101 ctatagttag tatacttata ttcactaaaa tagatacagc tattcctatt gtagatatta
     2161 tcgagccttc ttctgtacct gattcaactt ctgctgcctt ttgagctgct attgaacatg
     2221 gtagcctcat attagatata ttaccagaaa gaaaactcat ataagttcct gggataccta
     2281 agattggtga ataagaaact ggttctatta tgtaatttgg agcactcata ctgacaattg
     2341 ccattgtact tgctaataat gctgatattg gaggcataat accaaatcca aagctcaaaa
     2401 ttattccagg aactaatgct gctataatac ccaaagatag tgttagtctt ccatacctta
     2461 tcataaaagg taaatattct tcattgtata tagattttac tttactcata aaactccccc
     2521 cttatattac tgaagctatt atcattccgc taaacattga tattgtaagc ccccactctc
     2581 ttaaccattt tatatttttc ttcttttcaa gcatacacaa tattaccatt atagccattc
     2641 cacttataca tgcaattgtt ccattatcaa aacgcaacac cctatcagca tttagatatg
     2701 caaatgaacc caacattgct cctagagata ttattggtat aaatgatttc ttgccactag
     2761 atataacatt ggttatctta tctagtttat gtccaaatag taatgtgaat attatccatc
     2821 ctaaagaacc taatatcata gtccaaactg catttgtaaa tgcaagtttt gtcatttcag
     2881 gagaacctaa agttatacct aatgcatctg ttccaaatcc ggctgacatt gattcaaaaa
     2941 ttacagaacc tataaatgat aatctcatcc atgctatagg cccacccata gttactataa
     3001 gcgataccat tccagcaaat atagtcattg aaggcccaat agctgaaata gcactactct
     3061 taacagctga ctttatttgt ttatctgtta ttcccattgt tttaccaact ttgcaagatt
     3121 ttatagcaaa tataagggat tgtaccacta ctattgatac tgctactgta ctcgctatcc
     3181 acaaaagtgg atgattagct aattttaaat aatccattta taaaacctcc ctataaatcc
     3241 tcaaatttta ttaatatttc taatatatct atttccaaac ctgttttagt actctaagta
     3301 tatttccacc tagtaccttc tctatttcct catcactata tccatgcttt actaaatatc
     3361 taacaatgtt ttttgaagtt tctgttgggt tctcaagacc ttctacatat tctactttgg
     3421 gatgttcttt tgttcctgtt atttttttta tatcaaattt agcagctagt actgagtgta
     3481 attttacatg gtcgccatat actgtatctg gtccaaaagc tacatggtct attcctacta
     3541 aatttttaat atactcaaaa tgttccataa atgactctat tgaatgttct ttattcttct
     3601 ctgttattgt agtatgaggt gctgcttcta cacctataac ccctcctttt ttagcacatg
     3661 ctattaatac ttcatctgga gttagtctct ttgtgttcca taaacttctt gccccaacat
     3721 ggcttaatat tattgggtcc ttgctatatt ctattacatc aagtgtagtt tgaactccaa
     3781 cgtgagagca atctattgcc attccaattt tattcattct ttcaacagct tttttcccaa
     3841 aatttgtaag acctccatct ttctcttctt ttagtcctga acctaatgca ttggattcgc
     3901 tgtatgttat acccattaac cttataccaa atccatacag tatatctatt ctgtcaagtt
     3961 cattttctat tggtgctgca ccttctaatg ttggtatcaa tgctacttta ccttcacttt
     4021 tagctctgta tatatcttct actttttcac actttatgac aaaatcttga tgagctaaat
     4081 cacatagtct catgcctaaa tctattaata tatcatccca tttccaccct gaatttgatg
     4141 ttatcgtaca tacaccatcc attaaattat caaatatagc atcataatat cctcttgata
     4201 atgcttcata agcgcatctt tgtttacctt ccctattata ttcaaatata tctctttcta
     4261 ggtgttctgg aaataatact ggatgttcat gtaatgatat aaatattttt tcatccacta
     4321 tacttttaac cttcgcttct tgaatatcat ctaattcaat aaggtactct ttaactcttt
     4381 tatctccttt acacatctca atagatgaaa tatcttttcc tttttctaaa taactatagg
     4441 cttcatatcc tttgtaagct gacttcataa caacatcctc caagttctac aattttttat
     4501 atttttccta tgtagcaatt gatgtgccaa aatataaatt ttaattgtat aataaatctt
     4561 gcaaaaaata aaaacagtag taaggttgat atttactact gttttattaa aaataatctt
     4621 cttagattat ttattcaata tttttgaatt atcttaatct taaagataat tttatttatt
     4681 tctatccatt atagggattt ttttagggtg ttttgccttt ttagtcccct atatcactcc
     4741 cttaattttt acatatgata taaagttctt tccttcatca gttataaaac taccttgttt
     4801 ttttactcca gataaaagta aaccatggct ctttaactta tctattcttt ttctaatttg
     4861 gtctacactt aaaactatat ctttttcttt taaaatctct tgcagtttat ttcttcctaa
     4921 taatatattt ttattattcc aagtttctat actggtcaat atacatatac tttcctcaaa
     4981 gaaattagat tgtttgaaat ctaagataat tgaatcgaaa ttttcattaa ctaaagtatt
     5041 gtttttttca aatctaaatt gttctggcaa atgctcgtaa tctactctat cttcctcaac
     5101 tatagtatca atataataaa ttaaattttt aagctctctt acatttcctg gccattcata
     5161 caatgttaaa gcttgcattg attcctctgt aaaacatttg ttgctattta tttcatctaa
     5221 aaaatactta cttataagag gtatatcttc cttacgttct ctaagtctag gtatctctat
     5281 atgtaataca ttaatcctat aatacaaatc ttctctaaag gaaccttctt taattttttt
     5341 ctttaaatct ttatttgttg cagctataat tctaacatct attggtataa ttttacttcc
     5401 gcccattctc ataacttctt tttcctgtaa tactcttagc aatctctgct gtacatctaa
     5461 agatatatca cctatctcat ctaaaaaaat tgttcctgtg tgtgctcttt caaatatacc
     5521 cattttccca ccttttattg ctcctgtaaa acttccttca tcatagccaa aaagttcact
     5581 ttcaataagt gtatctgaca aagaagatag attaactgca acaaatggct tgttttttct
     5641 tagagattca ttatgtattg cctgggcaaa tatttctttt cctgttccat tttctccaag
     5701 tatcaacaca gaaaagtctg tagttgctat ttttcttgca atattaattt tttcttttat
     5761 tattttactc tcacctacaa cactctcaaa tgtatacttt gatacaaaac cttttgactg
     5821 aagtttattt tgaatcttgt cctcaagctc ttgaattgca cttatatttt taatgcttat
     5881 aatactcttt attcgttcat tattttcata aacatttact ttattaatta tcagtttttt
     5941 gttatttaaa tttactactt catcattaac ttcatcttct tgaaaaaata tttttttgac
     6001 aaccttatca ctaaataagt ccataaagtt attagatata atttcatttt ggtctattcc
     6061 aactagatta gaaaatactt tgttgcaata tataaatttt cctaatttat caacagaagc
     6121 aataccttca tctataatct ccaaaaaact cttcatggtt ttattcatag ttgtataata
     6181 cctatatcca cttactgtat cttcattgta tttttcctta ataatatgta atttatctat
     6241 agatatattt agttttgtaa agatttctat aactgtattt atatcaatta ccttatcacc
     6301 tatgtcaatt atttgcttta tgttttgtgg tatgctgttt ctgcttcctg taataattcc
     6361 aatctcacat ttagacttat cacaacctgg ataatatggt attagattaa tatgaattaa
     6421 tcctagtttt ctaattatct tggcagtttc atctgctgac tctttataag catctataac
     6481 cataacatca gaatcatttt ctatacttat tatctgattt atattttcaa tatttatagt
     6541 acgatgtact attacaatag gtatattttt atcaatatta ttatgtatat attcctttat
     6601 atcattgtct gaacatacta caagctcata gcttgacagt tcaatattta tcctatttac
     6661 atataccaag ttatctatat tataaaattc tccaaatata ttttccaatt gttttgatat
     6721 atctatattt attttgtcat cagttgatac aaataaaata ttatgttttt tcatagtccc
     6781 acctcctgtt taacgagtat agaaagtaat aatttggtct attgtagcac tttttaaaaa
     6841 agttttaaat cttaaaaatc aaattttgta ccatttacta ttattttcca taataaaata
     6901 atgtaagcta tttttttcac atataattta atttctaaaa cggttagttt gacattattg
     6961 gaatataaac aaaaatttaa tataaattcg ttaatatatt aatacatttt taagaatgat
     7021 aaggaataaa ttataacaaa ttttaggaat atataataat agggtctcag aacttagtta
     7081 caagttctaa aaccctattt gtttagtgta aaaaacatca taaaatttag cttaaatctt
     7141 ttcacataat attactcttt ttctaagtga taataaaata tatctattcc tctaaaaact
     7201 gtaaaaattc ctgattaaat agtttaagct catcatagaa tatagcatga ccactatact
     7261 caaaagtata taaaattgaa tcttctattt tttcattcat aaaaactgca aattcatacg
     7321 gacatatttc atctaatttc ccatgaaata taccagtagg cactcttaca cattttaaat
     7381 cattaaataa ttcttcatct cttaaagata cagcagttcc aatagtgcca atacctgatg
     7441 cactaaaacc aatatcatta aaccatcttc taaagctttc tggtggattt gatgcaaata
     7501 ctttttctcc aaaatcggtt accatttctg gtctatcagt acaggcttgt gctatcaatt
     7561 tatttacatc ttcacgtgtc ataccatatg gaaattctgg aggtctttgt acaaatgatg
     7621 gtgcagcagc tgcagctaat accaattttg acactccata tccattaaat aaactcatat
     7681 acctaagtac gattgctcct cccattgaaa aaccaacaag ggtaaagtct tttaatccaa
     7741 tagcatgtac caccttataa atatcgtctg ctaattggct ataagtatat cctcctgatg
     7801 ttgcatcaga tttaccaaaa cctcttaaat caattgaaac tgttctatat ccgagttttg
     7861 gcaatatatt tgtttgatat tcaaatatct tatgtcctaa gggccaacca tgtataaaaa
     7921 gtacagtttt tttagcactc ggattcaaat catatactgc tatgtttata tcattcacat
     7981 atacataata catatcaaca gcaactccct tcaagaaaat gtatgatggt tattttatat
     8041 atatgaataa aatgatgaat aactaaattt tcaaatttat ttacaatact tctctattgc
     8101 cttttcaaat aaacttacat gaagtttttc atctaggatt attctattta atatagcttt
     8161 tatataaggg tcttcaataa gacttatatc tttataataa ttattaatag ccacatgctc
     8221 caaatgcaaa tctagtttta atctgttaca aatagaattt ccataacata caaaaccacc
     8281 attccaatat gcaccacaag aacttgtaga acctctatat acaggatttc cacccaataa
     8341 tcttatagtc tttgctaata tctccatatg taacatttct gttatagata tatttatcca
     8401 catttcactt aactctctat gcgtttcatc taaatcaaaa ttatggtata gatattgatt
     8461 tacactcgta aattcacttg atactccggc atagtcatcc atcaataatt ctgcatagta
     8521 cttatttgga cctaaaactt ttatctctgg atatggctca tcacttgaat atccatttcg
     8581 cttgtgcatg tcataatgtg catcactcat aatatctcct cctttaaatt taatgtatga
     8641 tattaattgt atgcatcacg actttttcat ataacttaga taataaaatc tacttaaata
     8701 ataaaaagcc atattaatta aaattaacat gaccttttat ccacaaaatt actttttaat
     8761 tattcatctt ttccagctac tgatagctct ttaataacaa ctgaaggcga acctatacta
     8821 ctcattggaa attctaaatc tgctcctata gcttcaatat cttttaacag gtcaaaatag
     8881 tttcctgcta ctgtaatttg ctctactgga aatacttttt ttccttcttt gatataaaag
     8941 cctttggcag ctaaagaaaa gtctcctgtt actgaatttg cacctgaatg aagtcctgca
     9001 aagctagtaa ccatcaatcc ttcatctata tcctttataa tttcatctaa agatttatct
     9061 cctttctcta tataaaaatt agttggatat atgcttatag gtgatgaata tgaagatttt
     9121 attccatttc ctgtagtctt tacacctgcc ttattagccg tttttaagtt atgaagtaaa
     9181 gttataagct ttccatttaa aacaacttct tttttaaatg tagctactcc ttcatcatca
     9241 aaaggagtag atgccatacc attttctaaa agtgggtcat caactattgt aactatagga
     9301 gatgctatca tgtctccttc tctatttttc aataaagata atcctttttg agctgaatct
     9361 gcattaaata tcccagaaaa tgtgctaagc aaagatacca tagcttcatt aagcaatata
     9421 gttttatatt tacctgatgg aatactctta ccacctactt tagataaagc attatcaaca
     9481 ccaagttttg ctatctcaca aggttttatt tcttcaatag aatttgctat attatatcct
     9541 attccatcat atttttgtcc attgtcttct atgataggaa ctacaaaccc tataagcata
     9601 ttagttttat tacttaaatt aagaccttta gtattagata taccattact tgatacagaa
     9661 taagatatag tacatttaga taaatttacc accttatctg aataagcttt agtctctctt
     9721 tccatttcta aagctaaatc aatcaactta tctgcctcta aattttctag ctctttagaa
     9781 taagtcttta catcattata gtgcttatct ccttcatata taaattgtac atcttcattt
     9841 tcaatagtgt ttactccatc ttttacattt tttatcaaca tatcaacagc tttatcatct
     9901 aaaatttctg tataagaata acctatcttt ccatttacct tacctctaaa agataaacca
     9961 aaagatttat caagattgta tttctcaact tctccttcat atatatttat acttaaattt
    10021 tctcctgtat aataatatat ttcacactct tcaaaacctt cacttagagc ctttttaaat
    10081 aatatatctt taaaattttt aagttccaca attatccctc ctatcttcca cctacagtaa
    10141 tttcttttac ccttatcata ggttggccta cattagttgg tatacttcct gatgatgagc
    10201 cacacatccc ctgagcttgt tttacgttat tcccaaccat atctatattc ataagtatat
    10261 cgctaccttt tccaattaaa ctagcacctc taactggctc ttgtatttct ccatttttta
    10321 ttaagtaacc ttctgaaact acaaaattaa actctcctgt tacaggattt acagaaccac
    10381 cacccatttt tttagcataa agtccatctg gtattgactt tataatatct tctggtttat
    10441 cctctccagc agcaatataa gtgttagtca tccttgaagt tggtgcaaat ttgtagttct
    10501 gtctacgaga acttcctgta ggattcattc ccattcgtct accattaagt ttatctatca
    10561 tataagactt caaaattcca ttttcaatca gtatattctt ttgagttgga tttccttcat
    10621 catctatatt catagaaccc cagtagtttg gtattgtacc atcatctata gctgtaatct
    10681 ttgtggaagc aatctgttga cctaatttat ctgcaaatac agagttcccc tttgcaactg
    10741 atgtagcttc caaagaatgt ccacaagctt catgaaatat tactccacca aatccattat
    10801 ctattgctac catcatatta cctgcaggac aatttttagc atgcaacata gtatgcgcta
    10861 ctctagctga ttcttttgca taatattctg ggtctatttc ttcaaatatt tcaaaccctt
    10921 tacaacctcc aggaccttca aatccagttt gattttcatt acccttagat gcaattgaac
    10981 ttatccctag tctagttctt attcttctat cctcaacata tataccttca gtgtttgcaa
    11041 ttaatatttt ttggtcttta tccaaataac taacacttac ttgagatata tcattactaa
    11101 attcttttgc actcttatat gcaaccttca taacacttac tttatcttta tttcctattg
    11161 aatttggata aatttttata ttatgtatgt tatttatttt aatactgtca tttaatatta
    11221 cactttttcc atcttccaat ttacctaaag caacagcagc tttgtatgct acatccaaca
    11281 gactatttaa tgaattgtca cttgtataag catatatact tttcaatcct ttaaatattc
    11341 ttattcctat accataattt cttccaccta ttgcattttc tactttatta tctattaaac
    11401 taatagaatt atttatagtg tcttcttcaa aaatctcagc aaaatctcct ccagtaatta
    11461 gacatttttc taatacctta gaagctatat tttttgaaag cataaattta cctcctactt
    11521 taaattttta attaactttt attcaatctt tttacttgtt aacaaacatt atatactata
    11581 ttacttaaaa taaggtaatt atgaatatat tatacatatg ttttatacta aaatgttatc
    11641 acattttatc tatacatacc catataacta gataattaaa atgtataata ttatttgcta
    11701 tagaaaataa tacactcata cataataaat tttaggagtg aagtatatga atcaagaata
    11761 tgtaaaagga aatcctattt ttactaatat taataaagtt ccaagacaat ttccatacct
    11821 tactgatgat attgatactg atgttataat tgttggtggt ggcgtaactg gatgtatttg
    11881 tgcttactat ctagctaaaa acaatataaa gtctgtcatt cttgaaaaag gaaggattgc
    11941 acatggaagc actagcgtga caacttctct attacagtat gaattagatg acaatttgat
    12001 agatttaaca gaggttatga ctctaaaaga tgctctaaaa gcatacaacc tttgtacttc
    12061 agcacttgaa gaattagata catttataga gctatatgga aataagtgtg attatgccaa
    12121 aagagatact ctactttata ctgccaacaa acttgaagtt aaggctatca aagaagaata
    12181 taacttaaga aaagaaaatg gatttgatgt tgaatatatt gatgaatcca caaacccttt
    12241 tagctttgat ttaaaatcag gattgatagc aaagaatgga ggacgagaat tagacccata
    12301 taaatatagt caccatttga ttgatgtaag tttaaaaaat ggtcttcaag tatatgaaaa
    12361 tacagaagta aaaaaagtag atttatcaaa tgataaggtt actgctgaag tatcgtatgg
    12421 atacaaagtt catggtaaaa aattaattgt agctacaggg tacaatacaa gtttatttac
    12481 aaaaagaaat tttgcaacta agtcaaatac ttttaatata gcaacgaaac cacttaaaaa
    12541 catagcttct tggaaaaaca acattttaat tagagataac tgtgacccat ataattatct
    12601 aagaactact aaagacaatc gattaattat aggtggtgaa gatgtaagtt ttgatgatat
    12661 agaaaatgaa actttagcca atgaaaagta tgatatttta gaacaaagat tgaaaagtat
    12721 gtttaaggat ataaaagaca ttgaagttga atataaatat tgtggttgtt ttgcttcaac
    12781 tttagataat ttaggtttta ttggtccaga taataaaaat aacaatctat ggtattgctt
    12841 aggttatgga gcaaatggta tactctttgc aatattagga ggtataatgt taagtgaatt
    12901 atatcttggc aaacaaaata aaaatatgaa attatttaaa gtagatagat ttgataaata
    12961 gatattatat attaaaagac tgtaaaaaga tgaaacttta taattctaaa agttaacttt
    13021 gatacagtct tttataatgt tccttttaaa aatactttat ttataattaa atataaagta
    13081 aaatgttaaa atataactaa taaaatttag tcataagata atatttaagt ttatttgatg
    13141 aaatatggag gaattattat gaaggaaata ctcgttattg ctcccactaa aggaacctat
    13201 gaaaaatcaa ttcacatagt taaaaaaaac aaatatacaa atattgatgt tgtatttggc
    13261 aatctaaaag aaggtatacc tcttgctgaa aaaagtatta atcatggtac tagaattatc
    13321 ataagccgag gtggaactta caatatgtta aaagctactt acaatatacc tatagttgaa
    13381 attaaagtag atgcttatga tattataaaa agttacaaag aggtaaaaaa ttccaacgaa
    13441 ccatttggaa taattggatt taataatgtc atctacggtt tcgatattat agaagaaata
    13501 ttgaataaga aaataactat gattgaaatt gaaaaagaag aagaaattta tgatgctata
    13561 gaaaagtaca gaaagaaagg tataaacaca tatataggag ataccactgt tgcacatatt
    13621 gttaagagac ttaattgtaa gggaatatta atcgaatcta gagaagaaaa catacttaga
    13681 gccattcaac aagcagaaca aatactcgaa gcaaccaagg atgaacaaaa aagaagatta
    13741 cagatagaag ctatgacaga ttttgtacat gatggaataa taacagttga taaaaatttt
    13801 aaaataacat tatttaataa gagtgctgaa aaaatatttg gtataaaaaa agaaaatgca
    13861 ctttatcata atgttgtaga tgttatccca aacacagttc ttccacaagt agttgagact
    13921 atggaacctc aaattggtga aatacaaaat atagggagta caaaaattat tacaaataga
    13981 gttccaatca ttgttgatgg tcagattcaa ggagctgttt caacatttca agatagcaag
    14041 gagataagtt cttttgaaca tacaataaga aggagcttat taagcaaagg tctatctgct
    14101 aaatacactt ttgatgatat aattcatgct agtgaaaaga caaaagattg tatagaactt
    14161 gcaaaaaaat atgcttgtta tgatactcct atgattatta ctggagaatc tggagttggt
    14221 aaagaactat tttgtcaaag tatacataac tatagtaagc gtaaaaatgc accttttgtt
    14281 gctgtaaatt gtgctgccat acctccatct ctaatagaga gtgagttttt tggttatgag
    14341 gaaggttcat ttacaggtgc tagaaaaaaa ggtaaagcag gtatattcga actagcacat
    14401 gaaggtacaa tcttcctaga tgaaataagt gaaatccctc ttgaacttca aggtcgatta
    14461 ttgagagtat tgcaggaaaa acaagttatg agaattggtg gtgataaagt tattcctata
    14521 gatgtaaaaa ttatctgtgc ttcaaataaa gacttaaaaa atatgatgcg caatggttta
    14581 tttagacaag atctttattt tagaataaat atactaacat tatatcttcc ttcattaaaa
    14641 gaaagaaaag aagatattat aaaattatca gaatttttta tacataaata ttcaagcaaa
    14701 tacaataaaa cacccttaat tatcactcca aatattaaaa aggcacttct tgaacgagaa
    14761 tatgaaggta atataaggga attggaaggt atgatggaaa gggctgttat tgtggaatca
    14821 tttgactcga ttttattaga aaaggttagc aatgaatata caaataatat agttgataaa
    14881 gataatagtg attttgaatg cagtaattta gatttaaaaa ctttagaaaa aaaatatatc
    14941 tataaaattt ataacgaaaa taatagaaat actacaaaaa cctgtgaaat tctaaagata
    15001 actcgctcca ctctatggcg taagttaaaa gaaatagaag atgatgttta aaaataatac
    15061 atatctatat atatcaaaac gttttatgtt taattttaat acataagacg tttatttgtt
    15121 ttcaataaaa aatacaatta tatgataaaa agaatctttg taagtgaaat tctcgtcaat
    15181 cgtactttta attataagta atctacagca tttcaatcga ttattaaaaa taatcatgat
    15241 aactaaagat acaaactcta tatattggca tattaattgc ttttataata cctatataaa
    15301 aatgaaaggg agtgatacta gatgcacatc ttaaaatcag tgaaaaagat accaggagga
    15361 cttatggtct gtcccttgtt attgggagca ctatttaata cagtatgtcc acaagctctt
    15421 gaaattggag gattcacaac atccttattt aaaactggtg caatgagtat acttgctcta
    15481 ttttgtctat gcaatggagc tcaaatcaat atcagacaag ctggtaaacc attgactaaa
    15541 ggtatagtac ttacagcaac aaaatttata attggtgcag tattaggtat tattgttagt
    15601 aaatttattg gacctaaagg tataattggt attacacctc ttgccatagt tgctaccatg
    15661 actaattcaa atggaggtct atttgctgct cttgcaggtg aatatggaga ctccacagat
    15721 gttggagcaa tatctatctt atctctaaat gatggtcctt tttttacaat gcttgctttt
    15781 ggagtaactg gacttgcaaa tgtacctata gtagcactat ttgcagcact tataccaata
    15841 ctacttggat ttatacttgg taaccttgat gaagatatac gagaatttct tgcacctggt
    15901 acaacattat taattccttt cttcgctttt cctttaggag cagcattaaa ctttaatcaa
    15961 attataactg ctggactacc tggagttgta cttggtttag gagttactat aataacaggt
    16021 atgggtgggt actttgtaat gaaacttata cgtgcagaac atccagcagt aggtgcagct
    16081 acaggtacaa cagccggaaa tgcagctggt actcctgaag ctttagcagc tatagaccct
    16141 actctagcta caatagcagc tgtttcaaca gtacaggttg ctgctgctat tattgttaca
    16201 gcaatatgtt gtccaatgtt agtttcctat ctagataaaa gagaaaaaaa gaaaaaatct
    16261 atttttaaaa caaataaaaa tattgaagta aattaatact taaggaggta aaattaatga
    16321 atgcaattat tcatgcaaat gaaaaagata atctagttac atgtgtcaga cctttagtta
    16381 aaggtgaaaa agtttcaatt gatggaaagt cttacatagt aaatgataat atacctgtct
    16441 ttcataagat ggctacagaa gatgtaaaaa aaggtgatgt tgtatacaaa tacggtgaaa
    16501 tcataggaat tgcaacagtt gacataaaaa ctggtgacta tgttcatgta cataacattg
    16561 aaagtacacg tggtcgtgga gataaaaaat aggaggaagt taaaatgaaa ttaatgggtt
    16621 atttaagaga aaatggtcag tttggtattc gtaatcatgt tttaattatt ccaacatctg
    16681 tatgttcaag tgagacagct acaagaatag catcacttgt gcctggagca atagcaatcc
    16741 ctcatcaaca tggatgttgt caaattggtt ctgatataga gcttacagca aagacattaa
    16801 taggatttgg aaaaaatcct aatgttgccg cagttttagt agttggtctt ggatgtgatg
    16861 gtattcaagc aaaagaatta gcatctgaaa tagctacaac aggaaaaaag gtagattacg
    16921 ttgttataca ggaatgtggc ggaacattaa aaacagtttc taagggagct gaaatagtaa
    16981 gtaaaatggc tcgtgaagtg tcaaaagaag taagagttga atttggtatg agtgaaatta
    17041 cattagcact tgaatgtggt ggttctgacc caacaagtgg aatagcttca aacccttcaa
    17101 taggcgttgc atcaaacctt cttgtagatg aaggtggaag tagcatacta agtgaaacta
    17161 cagaagtaat tggtgcagaa catttgttgg ctacccgttt tgaagatgaa gaaatgaaag
    17221 ataagtttct taaatttgta agtgatgtag aaaaaagagc aattgctatg ggagaagatt
    17281 tacgtagtgg tcaacctact ccaggcaata aaactggtgg actttcaaca attgaagaaa
    17341 agtcacttgg gtgtatgtat aaggcaggca ataagccatt caaaggtgct cttgaatatg
    17401 ctgatattgt acctcctgat aaaaaaggat tatattttat ggatactcca ggtcaagata
    17461 tagattctat cactggtatg gtagcaggtg gtgcacaaat tgtaatcttt tcaactggta
    17521 gaggtactcc aacaggaagc cctatttcac cagttattaa aatcactggg aatagtgata
    17581 catacaacaa aatgccagac aatatcgata taaatgcagg tagaattata acagatggtg
    17641 ctaaaatagc agatataggt caagaaatat ttaatgaaat aatagaagtc tgtaatggta
    17701 aacataccaa agctgaaagt cttggtcata gagaatttgg catttacaga atttcatcta
    17761 cattttagat tgtaacaaaa tatcttttat aaatataata cttatgtaga tacataagct
    17821 aaaagttctt tctaatacta taaaaatttt ctatactgaa aaggaactgt atcaaaatta
    17881 ttttgaaaac agttcctttt tttaacctct tttactcaaa atattataaa ataagattta
    17941 aacaataaac gtatcttgat taatctctaa gaagacataa ataaagctaa atgtaaagtg
    18001 ggataaataa aatttaatat ctttgtatga aaagatattt ggtataatat gtctgagaga
    18061 attcttattt gtaaacaaat aaaggatgga ggatgaaaca aaagaatgaa ctttgaaaac
    18121 acaaaaaata aaaaaataat agctacttta ctattgacac tccttttaat cgtgtcatta
    18181 acatgtgtca cttttattat gaatctaaat aaagtaacac ataatgaaac agaacgatat
    18241 cttgtagaag tttcacaagg tatttccact acaattaatg tgaaatgtaa aagtatattt
    18301 aggacactat attctatggg agatacttat tttgagatta atgatagtga aaaagaagtc
    18361 aatagatact tatcaaaaaa attaaaatta tttgaatttg attggttagg tattatagat
    18421 tctaatggaa attttgtaag tgcccttaaa gatacaggta atgttaaagg acaagacttt
    18481 tatagaaaag cccttcaagg caaagaaaca attactcctg ttaaatcaca atctggtaca
    18541 tatggaattt tatattctgt accactatac aatggcgata aaattgttgg agctgttgct
    18601 gcttggaata ctattgatac tatgagaaat ttattaagtg tagaaagctt tcatggtgaa
    18661 ggattttccc aaattatcga ccaagatgga aattttattg taagttcagc aaacaaaaat
    18721 gctccaaaaa atgtggtaaa tttttttgac atgattaaac accaaggaaa acaggttgat
    18781 aaaaataaac ttgaagaaat gaaaataaac ttaaaaaaga acaaaactgg ttctatgtat
    18841 tatacattaa atgatggtat ttctaaggca atgcactatc ttccattaca agaagaaaac
    18901 ttatacctcc tttcaattgt tccaacaaaa acagcaagtg cacagtttga tttacttcta
    18961 aaaaaagcaa tcttcatcaa tattttaatt gttatactat ttttattgct tattatattg
    19021 attatgttta taaatcaaaa gaacagggca caacttataa aaatcgccta tgtagactct
    19081 gtaactaaag gttacagtaa agcacgtttt gatattgaag ctaaaaaaat tatacagtca
    19141 tcttcatcag aaagctattc attggtatct ataaatattc agaaattcaa acttattaat
    19201 gattcttttg gtagtgaagc aggagataaa acattaaagt acatacatga tgtcattagt
    19261 aattatctag aaccaggaga attgctttgt cgagtttcta atgaccagtt taatgtactt
    19321 attaaaacta ttcctcaaaa agaaattctt aagtacatag aaaatatcac caatgatatt
    19381 aatagtttca ataaaaatga agaatgtaaa tattttatag ctctatctat aggtgtatat
    19441 aaaattgatg acccaaatct acctttagtt tcaattcaag accgtgcaaa tgttgcacga
    19501 aaaaataata aaggaaacat tggaaatcat ccactttata catgtgtttt ttatagtgat
    19561 ttagagcgtt taaaaatgat taaagaaaaa gaaatggaaa atagaatgga ggaagcatta
    19621 aataataacg aatttatagt atatcttcag cctaaaatca gcctaaaaga taatactatt
    19681 gtaggtgcag aagcattagt aagatggcaa gacccaaata aaggccttat accaccagac
    19741 gagtttattc ctttctttga aaaaaatggt tttattacaa aactcgacca ctatgttttt
    19801 gaaaaagtat gtagtatgat aagaaaatgg atagataatg gagaaactcc aatacctgtt
    19861 tcagttaatt tttcacgtgc taatttaaat aatatagatt ttttagaaaa atacagaatg
    19921 cttcgtaata aatacaacat tcctgcaaag ctcttagaaa ttgaattaac tgaaacactt
    19981 gtatttgaaa atctccaaaa attaattaat ataatagacc aaatccatga agaaggtttt
    20041 caatgttcac tagatgactt tggaagtgga tactcttcac tcaatatgtt aaaagaaata
    20101 aaagttgaca cattaaaact tgaccgtgct ttttttagct cacctaatgc agataatatt
    20161 gctgaaaatc atgtaataga atctatagtt aatttggcaa aaaaattaaa tatgaatagt
    20221 atatcagaag gtgttgaaac aatcttgcaa atggattatc ttaaaaaaat taattgtgat
    20281 atgatacaag gatatgtttt ttcaaaacct ctacctcaag aaatatttga gaaaatgact
    20341 tttggaaaaa aactagaaga aaccagtatg gatagttccg tttaaataaa ataaaaaact
    20401 tgtctctata aaataatttt aatcatttta taaagacaag tctttttatt ttccaattta
    20461 attttatttt ctaaatttct tacactcggc ttgttttaaa ttcccttttt aagaataata
    20521 atacgattat catagcaata aaatctgcaa ctggctgtgc caaccaaaca ccatctaaat
    20581 taaattgaat tggaagtaca atgattaatg gtataaataa aataaattgt cttaaaagag
    20641 ttaaaaacat tgaatgttta actttactta tacactgaaa atacacaggt cctacaatag
    20701 aaatccccat tataggcaat gtaattagat ttaggcttat acctcttact gctatatcca
    20761 tcaaatctga atctttatta aatataccta caaatacttc tgggaaaact tgtactacta
    20821 aaaatccaaa tgacaatatg acaactgaca ctatgataga taatattaaa gttttctttg
    20881 cacgctcata ttgttttgca ccataattgt atgatattat agtttgcata ccttgattca
    20941 atccaaacac aggcatcata aacatcaata aaatagatgt aagtgctgtc atagctccaa
    21001 tagctaaatc tccaccataa acctttagag aattatttgt aaacatgtga gttatactta
    21061 tagctacttc catagcaaaa ggtgtcattc ctattgcaaa taccttcttt actatatctt
    21121 tattcaattt taagttacat ttttttagtt ttaaattgga cttccctctt ataaaataat
    21181 gtattaccca aaagaatact actatttgac agagtactgt tgctatagct gctcctttta
    21241 tacctaaatt aaatacaaat ataaatatag ggtccaatat caggtttaat acacatccta
    21301 caatcattgt ccttgctgct aattttggat taccttctgc cctaattgca ttattaagat
    21361 aaaatgcaac taaattaaat atacttccaa ccaatatgac actcatatag tcttttgcat
    21421 aaaatattga atctttactt gcacccaaaa taaaaagtat atcttctaag aaaactaatc
    21481 ctaatatagt tataattaaa gagataatta tagataatgt caaagcatta cctaatatct
    21541 tctctgcttc ttctctattt ctttcaccta actttataga caatcttgtg ctagcaccta
    21601 ctgataccaa cattccaaaa gctattatta gagtaaatac tggcatagtt acaccaagac
    21661 ctgcaatagc tatagagcca ataccttcca tagaaccaat aaaagctcta tctactacat
    21721 tataaagtga agttaccatc attgctatta ttgcaggtat cgaataccta aataataaaa
    21781 tccatatttt ttcatgtctt aatgcttctt gattctccat gttgtcacca tttacaccat
    21841 gtcataagtt atacaaattg gtttatttgt tcttgggtct gttgctattt ctgcatcaat
    21901 attaaataat tcttttagat tatccttcgt cataacatca tatgcatcac cttcacaaac
    21961 tattttacct ttcttaatac ctatcatgtg gtcagcaaat cttgctgcat tattaagttc
    22021 atgtattacc atgacaatag ttcttccttg ttttttattt agttcatcta ataattttag
    22081 tatctccaat tgatgtgcca aatctaaata tgttgtaggc tcatccagta ataatatatc
    22141 agtttcttgt gccaaagcca tagctatcca tgccctttgt ctttgtcctc ctgataaatc
    22201 ttccatattt ctatccttaa attctgcaat tccagtaact tctaaactcc aatttacaat
    22261 ctctctgtct tctttactag aattaccaaa tccactttta tgaggaaatc ttccataaga
    22321 aattaattct gaaacggtaa gaccactagg agcttgaggg ctttgtggaa gtacagccat
    22381 atcctttgct atttctttag acttcttttt gtagatgtcc tctccattta tatatatttt
    22441 cccactatta gggctaataa ttctacctat agttttaagt attgtcgatt ttccacaacc
    22501 attagcccct atgatggtag ttatttttcc ttttggtata tttaaattta aattttttat
    22561 aatatctgtg tttccatatg atacatttag attcttagta tttatacagt tcataacaac
    22621 accctttcct aatcatttac caacattaaa taaataaagt acggcactcc tattatagaa
    22681 actactatac ctactggtat ttctataggt gctagaagat ttcttgatat agtatctgct
    22741 attaaaagta ataatgttcc tatcaatgct gatactggta ttaatctttt atgctttggt
    22801 cctattattt ttctacctat atgtggagct attaaaccta aaaatgaaat actacctgct
    22861 actgctgtcg atacaccaga taaaattact gcatatatta taagtcttct tctttgtttt
    22921 tctacatcta caccaagact tatagatact tcatcaccca aatttaaaac atctatatat
    22981 ttagatttat aaatagttat acccataaaa atcactataa atggaagcac agctattaca
    23041 tatttccaac tggttcccca aatgcttcct gatgtccatg ccataaccct attaaattct
    23101 tgtgttgtaa atttcaattg gaatatcgtc aaaattgaag taaaagctat gtttacacct
    23161 ataccaataa gtagtaatct tgacgaattt ataccacctt tccatgcaag agaatatata
    23221 agaaatgctc caaataaagc tcctataagt gcaacaatag gcattgtaaa tacagtcaag
    23281 ttactcatac cttcatatac attaccattc ataagatata tataaactac tacaaacaat
    23341 gcagcacctg aatttattcc caaaattcca gaatcagcta aatcattctt tgtaactcct
    23401 tgaagtatta cacctgctgt tgataatgca gaaccaacca aaagtgctat tactattctt
    23461 ggtaatctta atttaaatat tgcaatttca tgattacgct gacccttccc taaaaaagtc
    23521 tttataacat ccattggttc tatagaaaat gagcccatat ttaaactcaa taaaaaagtg
    23581 ataaaaataa gcaccattaa aattgatata acaagtaatg ttttagaatt tatttttata
    23641 atatttttca tagtacctat ttctccccct ttctaacaag gtatataaat attggcactc
    23701 ctataagtgc tgttatagaa cctactggtg tctcatatgg aggatttatc atcctactta
    23761 atatatctgt atatacaagc aatacagctc ctaatactaa agagctcggt attatatact
    23821 tataatctga acctactatt cctttagcta tttgaggaac tataagacct ataaaaataa
    23881 tattaccaga cactgacaca gatgctccag tcattaatat tacaagtact atacatataa
    23941 atctaacaaa gttagttttt tgtcctaatc ctattgccac ttcttctcca agacttaata
    24001 tagttattct tggagccata ataatagcta aaataaatcc aataccacca gctacaaata
    24061 gcaattttat accttcccac ttcactccta caagccctcc tgatatccag aaacttaatt
    24121 gttgagatag gttaaaatac atagatattg ctgatgccaa agaaattagc aatgtaccaa
    24181 gagcgactcc tgcaagagct aattttacat tattaactct tcctcttgat ttagaactta
    24241 taaaatatat aaataatcca cttatacttg ctccaataaa tgcaaacatc attacactaa
    24301 aacttccatg tataagttga ggaagttttt tttgaagtac cagtgatatc gaaattgcga
    24361 atgtagctcc ttgtgtaatt cctataacag atggttcagc tataggattt ctcgttattc
    24421 cttgcattat tgccccagaa actgctaaaa accctccaac aagtgcagct gctattgccc
    24481 ttggaagtct aacatccttt actattctca tatttattcc atcttccatt tttatcaaac
    24541 tatctataac agttgataga ttcatatctt ttgccccaat agttatggat aatacaattc
    24601 caaatacaag tacaactata cttactaata tcaacaaata agttatattt tttttactca
    24661 gcttagtcaa ttatcctacc tccttttccc ttttaatcgt cagtataata tcatctatta
    24721 agtattttaa ttttaagatt tattaaaaat aggtgtgaaa aatgaatatc attatctcac
    24781 acctactaag ttaagaatta ctttgttaat tcatttttaa ctgattctaa taataactct
    24841 tttccaattg gattgtatga ttgactgaaa aatggaacag catcaagtat tgttacatta
    24901 ccatctttta ctgctcttat ttgagcccag atagcactat tttctaaatc ttttttatct
    24961 gcttctgtag caattacaac tatatggtct gcatctatat ctgttaaacc ttccatactt
    25021 accattggta gtgttattcc atcctgtttt ggcatattct taggtctagc taatttcata
    25081 tcatcattga ttagagtacc tattccacca tcactaaata ccataaattg acctgaactt
    25141 gccaacactg gtaaataagt tttttctcca ttcttttcta taacttcctt acctaacttt
    25201 gtagcttttt catcatactt ctgtagccaa cttttagctt cttcttcttt gtcaaataac
    25261 tttgaaacat cagttaactt gcttctccag tcatttgcat aatctttcat cataactaca
    25321 ggagctattt cttttaattg gtcatatatt ttttcttgtc tttgactcat tattattaaa
    25381 tcaggattta cttctaatat agcttccata tccatagtat ccatcattga gtgcccaact
    25441 atctttacac ctttaagctc ttctcttatg taacttggta atttatcagt ttcatatgag
    25501 tctacatttg ctgttgcaac aggcttataa cctgctaata atagttcttc actacttcct
    25561 gatatatcaa ctattttttt aggatttgat ggtatcttaa cctctccttt aacagattgt
    25621 acaactcttg tctctgattt atctttatcc tctgtattct tatctgaaca tgctgtaaca
    25681 agtactaatg tagttataat agatataaat attgcaagtg attttatttt tttcatgatt
    25741 acttctccta cttgtttatt atacttacat gatattgatt atcataagca catatttatt
    25801 atagcatttt tctattttta gtcaatatta ttttgtaaaa ggataaaaat tcctaattaa
    25861 tcttaattat atatagctta gataaggttt tcttatatta aacagtattt ttttaaagaa
    25921 ttggacacaa atacaatgac ttttcagtta aacaatgata aaatgcaatt tatagataat
    25981 gaatttagta aggaggattc aaaacatggt acatttagta tattgtgata atgcaggaaa
    26041 aaaaggagaa aaggtcttag ataaaatctt ggctggaaca aaaacaatgg ttattagagg
    26101 tgctgctggt agaaaaatac cacatagtag agtatttgaa gatgagttac tttattttat
    26161 ggaaaaagga actgcaaaaa tatctgcaaa agccactgtt aaaaaggtag aaaactatgt
    26221 taaattaaca gaagatgaaa tttctaaaat tttaaatgaa aatcaaccaa aattaaattt
    26281 atctgaaaag caaaaagttc gttggcataa aaaatgttta tgcttagttg aatttgaaaa
    26341 tgttgaagaa ataacacctc ttgattttga ccatcaagga aatatggatg attggcttat
    26401 tgttgaaaaa attgaagatg tagttgttgg tactagtata ccttacaatt atgagaagtc
    26461 taaattctaa agtatcaata acataatact atattgctaa actctactta aataaaaaaa
    26521 gagtgcattt aataattata aaaattattt ttatacactc ttttttaata ataaatttaa
    26581 attacttact ttctaatctt tcatatacat ctataaattc ttctgctaat tgttgaaaat
    26641 tcatagctgt cattaaatgg tcttgtgcat gaataagtat aacacttatt tcagttttat
    26701 taccattagc ttcattttgt atcaattctg tttggaattt atgagcttta tgaattgatt
    26761 ctttcgactt ttcaatacat tctctagctt tatctatatt cccgctcttt gcttctttta
    26821 ttgcttcaaa tgctagccct ttcgcatcac ctgcaaatcc aattattcca aaagatatct
    26881 ctatcatctt ctcatccatt tattcgacct cctaaatatc tctatagctt gatatgacta
    26941 atccattctt ttctaaaaat tctttgactt ttttagatgt aagtatcttg tgctctttcg
    27001 ttctatcaat agcataagat gtagaattta aaatataatc atctaaaaaa gctgggtgag
    27061 acataatatc cactacatca tacttcatta tttcgtctat attttttata aaatattctt
    27121 cacttacatt ttccttataa aaactatcta ttaaaggaac tactttagaa tactctaaat
    27181 tatattcaaa tccacctctt atcggaagat tatacttggt tacaatcttc tctattactg
    27241 gctttaaact tactaaagta tggatatgat ggtgactatc taaatgagat atatctattc
    27301 caagcccttt taccctatct atttgagcac aaagttctct ataaatctca tcacaatcca
    27361 ttttttcaat aatttcgtct gtaatcctcc taataaaaaa accgtcttta tcaacaatag
    27421 tttttaagtt agataataat ggtctaccac aacttaaagt catatgaact ccacaattta
    27481 aagttttatt ttctttaagt aagcctactc catgttctac cccaggcata tttgccatca
    27541 tagaagtaga cctaactata ccattattat gagctgaaat tattccatag ttcacagctt
    27601 cacaatatcc aaaatcatct gcatttatta taattttagt cataccataa cctactttct
    27661 atagacaact atctattaaa tctaggaaga taatctttat gagcttccaa catttcgtct
    27721 aatatagttt ttgctaagtc atcagatgga atcaatgggt ttgtacaaag tgccaaaaga
    27781 gcagattcat aatcgccata tacagctgct ttagctgcca atacttcaaa tgatttgatt
    27841 tgacttacta atccatgcac agaatctggt aaatatccta tacttattgg ttttggacca
    27901 ttttttgtta ttacactact tacttctact gcttgttcat ctttaaaatc tcttatagaa
    27961 cccttgttta atgtattaac tacttggata tcttttttgt cattgtatat agaacttatt
    28021 aaattacaag cagcatcact atagtaagcc cctcctcttt tttcaagttg aggtggtttt
    28081 acatctaatt tttcatcctt atataattca aataattgtt cttccaattc tttaactact
    28141 tgacctctag cttttccctc tttaaactct ctcaactcat cctcaagcat ttctttagtt
    28201 ttatagtagt atctatgata tggacaaggt attgcaccca aagattttac aaattcagca
    28261 ttaaaatcaa ttgcctttat attttgcata cttatatctg ctttgacaaa tttatcaatt
    28321 gcttcttttg taacatcttc tccatctaaa gatacattta gaccataaac catatgatta
    28381 agacctgcaa aatccatact tattctgtca ctttctacat taaatagttt ggcaacatca
    28441 ttttttaaat gaattggcac gttgcataga cctatatatc ttctaaaatt agtatatttg
    28501 aatacagcct ctgttattat tcctgttgga tttgtaaaat tcaccatcca tgcatttgga
    28561 cataattctt ccacatcttt tattatatca aatataactg gtattgtgcg aagggcttta
    28621 aataaacctc cagcaccatt agtttcctgc cccataactc catgagataa aggaatagtt
    28681 tcatctttta ttctcgcatc taaaagacct actctaagtt gtgttgtcac aaagtctgca
    28741 tctcttagag cttctcttct atctaaagta agatttattt tcatatctac tccagctttt
    28801 tttaccatcc tcttagctag atttccaact atctctaatt tttcttttcc agcttctata
    28861 tctacaagcc ataattcctt tacaggtaac tcttcatatc tatttataaa accctctaca
    28921 agctcaggag tataacttga acctcctcca attgtaacta tttttagtcc ctttttcatc
    28981 tcattatacc atccttacct ataatttaat atactctaca aaaccctata catttattta
    29041 ccgaaataaa actacctagt tgttaatttt caatttatta gcttccattt tttcagacgc
    29101 tatgacaaat ggaatatata ttaatattga taatattaaa ttaaatagtg ctaaagctcc
    29161 accagtccag tcacctgtag ccattgctcc acctaatata ggaggtgtta cccaaggtat
    29221 tttaggtaaa attactggtg ctactaatcc aaaatctatt gctaagtatg atacagcact
    29281 acatattact ggtgcaagta caaatggaat cataaatata ggatttaaaa ctattggaag
    29341 tccaaatatc aatggttctc ctatgttaaa tattgcaggt ggaccaccta atactatcat
    29401 ctctttacgt cttcttccag ctattaataa agctactatt aatcccaata ccattccaga
    29461 accacctaaa tacacaaatg catcaaagaa tgcacctgca agtacatggt atccttccgt
    29521 tgctcctgct tgagccaagg cagcattttc tccacctaat ttcataagta tagtttctgt
    29581 aaaaggaagt gctatatttg caccatgaag tccaacagtc caaagtatat gaattataaa
    29641 tgcaataagc attgtagaac ctagactatc agctacattt gatagtggtg ctcctaaata
    29701 agtatttaaa atatctgtta agaaacttcc attagaaagc atttttataa atattcctat
    29761 tacagtaaat atcattatag ttaacattcc tggtattaac tttgcaaatg atcttgaaac
    29821 tgctggtgga actccatctg gcatttttat agttaatttc tttaccttag ataatcttac
    29881 aaatatctca gttgataata atcctattaa tatagaagag aataaagctg ctgtacctaa
    29941 gtaggtttgt tgtatcattc cccatccttc aactactgta gttcctccct caggaactat
    30001 tttaccaatt tgtggagcca ttataaaaaa gatagataaa gctataagcc cagattgtaa
    30061 cccatcactc tcataagatt ttgctagaaa ataagcaaca cctattacta agaatactgc
    30121 cattgtacct attgctcccc accaaaggtc gcctccaaat gtggtccagt tttctccaaa
    30181 tatacttgcc atcaaatttt tgtatgcttc caatggtaag ttatttatca atgttcccaa
    30241 tgcacctacc atagttatag gtatcattac tataaatgca tctcttactg ctactaagtg
    30301 cctttgagct cctattttag cagctacagg cactatatat ttatccataa atgacatgaa
    30361 tttttccatt ttacatcctc cagtacaact ttattttgaa ctatttaact ctacagctct
    30421 atctaacaca gcttttccat tacatcttcc ataatccatc atatttataa cttctactgg
    30481 aatattatat ggttttgcca tttcagttgc ttttcctaat acatatctaa cttgaggccc
    30541 taaaagtaag acatcacaat tttctatttc attttttaag ttcacttctg atatagccca
    30601 tatttttgct tctataccgt tttcctttgc tgcatcctcc atttttgtaa ctaataaact
    30661 agttgacatt cctgctgaac aagctaacat tatttttatc attttttccc ctccaaatta
    30721 gattcattaa atatttttta agtcataagt tttttaaact atacatttaa aatatgcttt
    30781 tctattaatt ttttcttaat gtatatatct tatttttaaa tgtatataca tttaattctt
    30841 gatattatta tataccaaat gtatatacat ttcaagaaaa ctttttcatt ttatttaaat
    30901 tttattcgac aacagcattc aaagttaatg tatatccata gtgatatgtg tgtgagtact
    30961 caaaaatctc actattttgt aacttacaaa tttggcttat atataaaagt ggctctggtt
    31021 cttctaattt tagattatcc atacactctt cattcgatat tacagcttgt acttctctct
    31081 ctgacatggc tatcttgtat ccacacactt cttcaacaaa attataaaga gaattttcac
    31141 aatgagtctt atttaaattt ggaaataact taactggcat ataagtaatc atatatgaaa
    31201 ctcttgcatc attggctaat cttactcttt ttatttccca aacattttct tctaaactta
    31261 tattcaactt acttgataaa ttttcatctg cctgaactat ttcaagagat accaatatat
    31321 tagatacttt atagccttta ctttccatct ctttagtaaa tccacttaca gacgatatat
    31381 tatcatatat attatttgca ataactatac tacctacacc tctttgtcta gttatatagc
    31441 cttctttaac tagattatta agtgcagacc ttacagtcat tctagttaca ttaaattctt
    31501 cactcagctg tttttcagaa gggattaaat ccccttcttt caaactgtct gaatttatta
    31561 actctctaac atgattttct ataactttat aaattggctc tttcatttaa ttcactcctt
    31621 attaaatctt ttatataata agataatttt atatacaaac aaagaaaatg tctatacatt
    31681 taagataatt taaattttat tcagaaatct tgtacaactt tccgagtttt aataaagata
    31741 taaatagact tatcattaat atacctttta atatacttga taaggttata ctccaccata
    31801 caccatttag acccaacatt tctggtctag atataaagta agccaatggt actcttgcac
    31861 cagtcagtat agtaattata atagaaggta tataggttct ccctaatcct ttgaaagctc
    31921 ctgttgttat tatttctaaa cacataaaaa attgagaata gcctaatatt ttaagataaa
    31981 ctgctccttt ttctattgcc tcactttcat ctataaaaat agaaaatata ctctctcctg
    32041 caaacactaa tactaaagta gttattatac caagtacaga agatacagtt atagctattt
    32101 tgcaaccttt atttattcta gaatacttct tggcaccata attttgtcca acaaaactgc
    32161 ctaatgcaac tgatagccct tcagccgtca tccaggaaat tgcttctatt tgtgagccta
    32221 ctttttgtac tgcaacagcc acaggccccc atgatgctac tattactcct aatagcattg
    32281 agaatactgt aaacatacca ctttgtattg ctataggtaa tcccaattta tacagaactt
    32341 tataatattt agtctctatt tctttaaata gtcttaattt aaaatattct tctttacttt
    32401 taactattat atatataaaa catgtagtaa ctactatctg agcaaataca gttgcaatag
    32461 cagctcctgc aacaccaagt tttggagcaa atccccatcc aaaaattaat atagggtcaa
    32521 gtataatatt agttattaat cctactgtat taatacgaaa aggagtttta ctatttccaa
    32581 gaccattgaa aattgcagta aatactggat taataaaata aaataccata cctagagcta
    32641 ctattatcaa atactgtcta gacatggtta taacttctaa gtctcctaat ctaaaaaaac
    32701 ctatcaattg tttattaagt actattaaag aaattgtata tattattgct agtataatat
    32761 ttatttctat tgctgacttc atatatgatt tagtagtgct tatattattt gcaccaatac
    32821 tttgtgctac ttttatctct ccacctactt ttgaaatcat aataaatgcc attgcaagcc
    32881 atggaaaaaa accagctgtt ccaactgcag ctactgcttt acttccggct ttaccaaccc
    32941 atatcatatc tatcatgtta taccccatct gtataaatga agtccccatt attggaagtg
    33001 atagcttaag taatttttct gtaattcttc cttctgttaa attaagtctg tctttcattt
    33061 tccacctctt ttatattaaa tttatttgct tatatagcta gattaatcat tttatttgat
    33121 tgagttcact atccttcaat ttatattatc atatctcagg attgcatctc aatcatactt
    33181 atgtttaaga tacagtattt tacctatcta tgataaaatt aatacttatg aatataaatc
    33241 tagccatttc atcaatacat attctaaccc ttaacttaac ttcaattaag tatacatatc
    33301 gtaaccaatt agaatatttt atacggtatc ttccattaat aaacaaccaa tatcaatgat
    33361 ttatatataa ttttatttat acataaaata gtatactata ataataaaaa aactatattt
    33421 gaatgcttta agcatgttta ctaattgtaa tttccacaca aatttgataa tatatgaata
    33481 tattatggtg aaatttatag atatatatta attatgggga gattgtggga ggttcttttc
    33541 acaagacatt taagctatga aaataaataa aaaattcaat agagttgata tgcaggtttc
    33601 aatacttact gcaattattg taataatatc ttcctcatgt gtatattttt ttaattatac
    33661 actaacttat aagagcatga tatactcttt aagtgagagg tcaaaacata tctatgaata
    33721 tgtagaaaga aatattgata aaaatacctt tactgaaatt aattctaaag aagaccaatc
    33781 aaaaaagtct tataaaagtt ctaaaatcct tttagaatct gtaaaaaata ctactggagt
    33841 catgtatcta tatactgcta aaaaaacaaa agatggatca ctagtatatg ttgttgatgg
    33901 tttaaattca tctaggagtg attttagaaa tgctggtgat ttgatagaaa aagagatttg
    33961 gggagacctt aacaaagcat tagataatca tatattgtta cctaaaaaga ttaaatcaac
    34021 atcttgggga tacatattta tatcgtattt tcctattcac aatgatgttg gtaaggttgt
    34081 tggagtaata ggaattgaat ttgaagcaaa acatcaatac aatacattta aatttataag
    34141 tatagttaca ccaataatag cattattaac ttgtctaata tcagcattga ttgcagtgat
    34201 tctatttaaa agaatatcta atcctacata tactgatttt gctaatacag attatttaac
    34261 aggcctaaaa aatagaaatg cttttgaaat agatatgaat aacttaaaca attcaaatct
    34321 aaagaatcta atatctatca tatcaataga tttagacggt ttaaaaaaga ttaatgataa
    34381 atttggccat cagacaggag acttatatat taagcaagca agtaaaatta tacaatatgt
    34441 aataaataaa aaatatatag tttatcgtat tggaggtgat gaatacataa ttattctaaa
    34501 aaatttatct cacaaagaaa taaataatat tataaataat attaatttaa aaatagttga
    34561 agaaaactca actaatgaat taaaattatc aatgtctatt ggatatgcta tttttgatga
    34621 aaaagtagat gtttctttat ttgatacata tcgtcgtgca gattctcaaa tgtatgataa
    34681 caaaaggaaa attaataaac aatatcaata ataaatttaa aaagtctatt ctttaaataa
    34741 taaatcacaa gaatagactt ttttaaattt gtgtttttat aagataaatt atttaattaa
    34801 agtttgttct tttttctaaa cgattcttta taaattcata tattactttc actaatatat
    34861 ttgtgactaa tattaacaca gctagtgctg ctgcctgtgc agtactcccc ttatcatcta
    34921 gttgtacaat tgatattgca gctacttttg aacttgcagt atatataaaa actaatgctg
    34981 atattgtcac catggagttt aggaaaaagt acataaagtt ctctaaaact gctggcaaac
    35041 aaagtggtat agttacgttc ttaagaattg atgcgctgtt tattcccatt gatttagcta
    35101 ccatatctaa ttctttatct actttcttaa tagcagtagt agctgttata aatgctactg
    35161 aaaagaaatg aactatatta catataacca ttataagtaa tgttccatat aatccattaa
    35221 acaaattctt aatgtatatt gtatccataa aattaaactc taatttatta aaaaataata
    35281 cataagctat acctaaaact aatcctggca atgccatagg caatgtactt aaaaaatacc
    35341 caaatgattt taaatatgga gctttttctg ttttttcatt caaatatgca aataagaaaa
    35401 caaagctcgt ccctagaata gctgtaaata gtgacatttt tattgaattt ataaatggtt
    35461 taatcccatc aatactgttt ttcatagaaa aatgttccag tgtcagtctt aaatcatatg
    35521 gccaaactga tattaatgaa gataagatta cagttaacat tacagctatt ataccaaatg
    35581 caataattcc tacaacccct cctaaaatac tatctcttaa cttattagtt ttaaccttat
    35641 atggaattga ctttgaagtt atatatgaat tttgattttt ttcaattttt ttagttacta
    35701 taaacgatat tattgcaggt attaaaagta atattgatac agttgctccc attggcatat
    35761 tctgttgccc tataatttgc ttatatacat ctattgataa tacattaaac tctcctccta
    35821 tcacctttgg agctccaaaa tctgtaaaac ataatgtaaa cgatacgaat gcagaactta
    35881 ttaaagagta ttttatactt gggattgtta tgcttataaa ttctcttatc ttgcttatcc
    35941 ccatagtatt actagcttca tatagtctat aatcggttga acttagagat atataaagta
    36001 tttgaaagga ttgaggaaat acatatataa tttgtgccaa tattattccc actgctccat
    36061 atattggaac atgcactcca agtaaattag ttaccaaacc ttgatttcca aataaatata
    36121 ctagacctat tgcatgcatc attgttggag caaacatagg aaacatagct aatgatttaa
    36181 aaaaaccttt aaatttaatc tttgttctag ttaatgcata tgcatatact aatgcaagtg
    36241 ttagtgatat tacagttgat ataactgata caaatactgt attttttaga gaatttaata
    36301 gagattcaga agtcaagtat tcttgaaagt tttgtaatcc tacaaagact ccatctttat
    36361 ctaaaaaagc ctgtacaaat agatatatta taggtgctaa taaaaatatt actaaagaca
    36421 taactaatac tgtaagcata cattttttta tatctaaatt catttttgat ttaagactta
    36481 tacttttaga acttatagca ttattattca tacacttatg ctcctttaac ttttggatac
    36541 tttaaatagt atttttcgtc tatacttatt tttacaaggt caccttctac taaatttaaa
    36601 ttaacccact cttttataga aacatcactt attatgaaat tttcatttaa tttatctttt
    36661 atttcaactc tcaataaatt ccctctaaac tctatatttg atattatccc ttggtagttt
    36721 tcttttgtcg atttctctat ttgaacatat tctggtctta cagttaatat agaatctcca
    36781 ttatcaaaac agtttgtatc tcctataaat tgagctgtaa ataggttttg aggattttgg
    36841 tatatttctt ctggagtccc tatttgcatt atatctcctc catttagaat agctatttta
    36901 tctgccatag ttatagcttc ttcttggtca tgtgttacca ttattgtcgt tatattaagt
    36961 tctttttgta atcttttaat gtccattcta agcttgtgtc taacctttgc atctaatgca
    37021 gacattggtt catctaaaag taaaaacttt ggttcaagag ctaatgctct tgctattgca
    37081 atcctctgtt gttgtccacc tgataatgct ttagggtatt tatgagcttc attagtcaat
    37141 ccaactgttt caagtacttc cttaacttta ttatctattt tttcttttga aacttttctc
    37201 tcttttagtg gaaaagctat attgttataa gcagtcatat tcggaaataa tgcatatgat
    37261 tgaaatacta taccaaaacc tctctttgat ggctctaaat ttgtaatatc tttatcctgg
    37321 agaattatag ttccactatt tacatcttca agacctgcta ttattctaag taatgtagtt
    37381 ttaccacatc cactaggtcc gagtaaacat agaaattccc cttcttcaat atccaaacta
    37441 atattattta aaaccttttt ttggtcataa cttttaaaca cattatttat ttttaagtaa
    37501 ctcatatctt atctctcctt atatagttat ttttttattt taaattttat atcctacttt
    37561 ttcttctaaa attctttcat ctaaattatt aatttaaact ttacttactt tcagattttg
    37621 aaccgtattt tgattcccaa gttttaagta ctgtacttct gtttttggca gcagagttta
    37681 aatcaacttc ttttataagc tgttcaaatg gttgtttaga ataacctttt ggaactggat
    37741 tatctgtctt tatggaagta actgctactt catgtgcata tctatccata gctgaatcac
    37801 ttattgccca atctaaaaat agctttgctt ctttttttat attatctttt ttaactaagg
    37861 catttgcttc taagtcccaa cctgaacctt cctttggaaa tacaacctct ataggttctc
    37921 cactagataa ttgttgtgta gctctatatc caagtgtaat acctattgga tactctccag
    37981 agccagctaa cttcgcaggt tttgaacctg agtgtgtata tgtggctata tttttatgta
    38041 atttatccat gtaattgtaa gcatcttttt cacccatcat ttgaataagc cctgatactg
    38101 taagataccc cgttccagat gatgctggat ttggcattgt tataagtcct ttatattctg
    38161 gttttattaa atcttcataa ctttttggaa tatctatacc tagtttctta agttccttat
    38221 aattaactac tattgctgtc tctgggacac tcattcctac ccaagacaca tcatcttcag
    38281 tatctttaaa ttttttatca actttatcat aatttttagg cttatatgct tcaagtgcac
    38341 catctttttt tagctctatc atgttcattg ctgataatcc ccatataata tctgcttgtg
    38401 gattatcttt ttctgctaat agttttgaag ctattacacc atgagaatcc ataactatct
    38461 ctacatctat attgggatac tcttctctaa aaccttccat ataataagct atctgctctt
    38521 cctctagtgc tgcatatatt gtaagtttat tatttccttt tccttgagta gtttgtggtg
    38581 ttgttgatat gcaacttgtc ataaatgtaa tcactacaat gcacagacaa gtaaatataa
    38641 attctttcat atcttccccc tttgtgtttt ttcctttttt tatttgtttt ttattgtttt
    38701 tgcttatgtt tatataatac acctaatttg ttaatataaa gttaagtgta aattaacagt
    38761 tcgttaattt ttagaaattt ttgttaaata tattattttt agttaaatac agtctgtttt
    38821 taaacaatat attaattttt atagtatcta cattttaatt taaacataaa aaataagtct
    38881 aacctctata aagtagaatg ttagacttat ttttataagt atttaattat acaaccaaat
    38941 catttttttt cttttcttca agtgcttttt taagcaccat atccttaacc ttcataagtc
    39001 tagtagtact tgctctctca ttttcttcaa gcttcatagc tatatactta atagtctcaa
    39061 tgtaatttgg tatcattaca ttttcaagag cattaacacg tctacgtgtc ttttctatct
    39121 cttgtgcaag aagctgtgca cttttttcac tttctgcaag tcttaaaagt ggttgcatag
    39181 catctgagaa agcttccata gcagaatcta attcacctga tgtaaaagca agaccataag
    39241 gataaatatc actttgattg ttttcagttt taaagtcaaa cacaggaaca tcaacactca
    39301 ttatatttct cgtagaaaca tctactgaaa ctgattgctt tggcatcata agtgctgaac
    39361 ccagatactc ctgactcata actgctcttg cgattataaa gtttttataa gcagtatcaa
    39421 gagcattttc tgcttcttca cgcaatcgct tattttctct tacaatctca agaaattgtt
    39481 tcataagttc atcaagttta tctttaagaa gcttatgacc tcttgtagca gttttaagga
    39541 gtttcttaag tctagtcatt tccatacgtg ttggatttat atttaatcta gccacagata
    39601 tcactcctta ggcatatatt tttcaaaata ttcatcacgg atacgtttaa gttcactttt
    39661 tggtaacata ctaagaagct tccatccgat ttctaatgtc tgctcaatag ttctatcagt
    39721 tctaaatcct tgtgaaacat attctttctc aaattcatct gcaaacttag catacattaa
    39781 atcaatctca gaaagtgcag attcaccaag tatagccata agttcttttg catccttacc
    39841 tcttgaataa gctgcaaaaa gctggttcat tgtatctgca tggtcttcac gagtcttacc
    39901 tttaccaata cctttatctt ttagacgaga aagtgatggt aaaacatcta taggaggctg
    39961 tatatctttt ttataaagtt cacggctaag tataatttgc ccttctgtaa tgtatcctgt
    40021 aaggtcagga attggatgtg tcttatcatc ctcaggcatt gtaagtattg gaatcatagt
    40081 tatagaccct tcatgccctt tcatttttcc tgctctttca tacatagtag caaggtcagt
    40141 ataaagatat cctggatatc cacgacgtcc tggaacttct tttttagctg ctgaaacttc
    40201 acgcaatgcc tctgcatagt ttgtaatatc cgttattata acaagtacat gcatatcttg
    40261 ctcgaaagca aggtattctg ctgctgtaag tgccattcta ggtgtagata cacgctctac
    40321 agctgggtca tttgcaaggt ttacaaacac tacagaacgg tcgattgcac cagttgcttt
    40381 aaaatcgctt ataaaaaatt cagcatcttc aaaagttata ccaactgcag caaatacaac
    40441 ggcgaactta gaatcagttc cacgtacttt tgcctgtctt gcaatctgaa ctgcaagatt
    40501 ggcatgtggc aaaccagacc ctgagaatat aggaagtttt tgccctctaa ccaatgtatt
    40561 aagtccatct atagcagaga ctccagtttg tataaactcg gccggataat cacgtgctgc
    40621 tggatttatt ggagctccat ttatatcaag tcttttatct ggtataattt ctggacctcc
    40681 atcaataggt ctacccattc cactaaaaac acgacctaat atatctggtg aaactccaaa
    40741 gtcaagactc tttcctaaaa aacgaacttt actttcagca aggtttatac ctgttgagct
    40801 ttcgaaaagc tgaacaagtg cagtatctcc atttacctct agaactttgc aacggcgaat
    40861 ttctccattt gaaagttcaa tttctccaag ttcatcaaat tttacacctt ctacgccgtt
    40921 tattaacata agaggaccgg ctacctcttg tattgactta tattccttta tcatagttct
    40981 tcagcccccc tctttttaat aaggtctgca agctcgttgt ctatttcatc ttcaattgaa
    41041 tcgtaagctg catctatatc gccttcttct acatacttag cacgaccaat cttttcaaga
    41101 actgaaagct tgataatatc gtttatagta acattttgct tgatagcatc ttgtgctgac
    41161 ttatagaatt ttaatataag tcccatcatt ctatattgtt tatgaagtga tgtataagta
    41221 tcaacttcat ggaaagagtt ttgatgaagg aagtcttctc ttatagaacg agtaacctct
    41281 agtatcaatc tatctccatc tgaaagtgaa tcaacaccaa ccaattgaac tatttcttga
    41341 agttcagatt caacttgtaa aagtttcata gcttgagctc tttgagctga gaaattatca
    41401 tttacatttt tatctgccca tacatcaact ttttcctgat agagtgaata actagtcaac
    41461 cagttaattg ctgggaaatg acgtttatat gctaaagatg catcaagacc ccagaatact
    41521 tttactatac gaagagttgc ttggctgaca ggttctgatg tatcaccacc aggaggagaa
    41581 actgcaccaa ttgctgtaag tgttccttct ctttcatcca tacctagaca atttaccttt
    41641 cctgctctct catagaattg agcaagacgt gaacctaagt atgcaggata accttcttca
    41701 ccaggcatct cctctaaacg accactcatc tctctaagag cctcagccca tcttgatgta
    41761 gagtctgcca taagtgcaac actatatccc atatctctaa aatattcagc tattgtaata
    41821 ccagtgtata tagaagcttc acgtgcagca accggcatat ctgatgtatt tgctataagc
    41881 acagttcttt gcataagtga ctcgcctgtt cttgggtctt ttaattcagg aaattcaaga
    41941 agaacatctg tcatttcatt tccacgctcg ccacagccta tatatacaac tatatctgca
    42001 tctgcccatt tagcaagctg atgctgtgta acagtttttc cacttccaaa aggtcccggt
    42061 atagctgcta ccccaccttt tgtgattggg aaaaatgtat ctataactct ttgacctgta
    42121 acaagaagtg aatctggtgt tttcttttct ctatatggtc tttcttttct aactggccat
    42181 ttttgcatca tagttacagg tatatcatta cctttttcat ctgtaataac acaaactgta
    42241 tcttcaacag taaattcacc agaatatatt tcttttatag tacccttaac tccataagga
    42301 accataattt tacattctac tactgctgtt tcttgaacgc caccaattat atctcctgct
    42361 acaaccttat caccaacaga ttttttaggt ttaaattccc acttagttgt tctatcaagt
    42421 gaagatactt caacaccttt agttatatta gtacctgaaa tatcatacat tttttcaagt
    42481 ggacgttgaa taccatcata aatagttgaa ataagacctg gtccaagttc aacactcata
    42541 ggcattccaa gagaaactac ttcttcccct ggtcctagac cggaagtttc ctcataaacc
    42601 tgtatagaag ctttatctcc atgcatttct ataatctcgc ctataagatg tttatctgaa
    42661 actcttacga cgtcaaacat attcgcatct ctcatgccct ccgctacaac aagcggtcct
    42721 gacaccttta caattgtgcc tgttttcata ttctctcacc tgcaatcata tactttatca
    42781 aaatttaaat attccctcct atattttatt agcacatata tttagcacca ataaaatttg
    42841 agattgtctt ttattcaact ttcatctatt ctttaaataa tatatctgca cctatagcac
    42901 gtttactaga ttctcttact tcattcatac ctaatcccat acttcctcca atacctggaa
    42961 taactataat ggcaggaagt tggtaatctt tgtattttgc tattgattct tttgcaagca
    43021 atgatgcctg ttctgtaata taaattatcg catattcatc ttcaaccaac ttatgtatac
    43081 tttttttaat ttcgtcacta tcataggctg ggaagatatc tattccaaga gctaaaaatc
    43141 ccatgatgct atctttatct ccaactactc ctaccttata cataagcatc ccttagcctt
    43201 tcttttatag tatctgcgtc tatattatta agcttactag tcaaaataat tctaattgtt
    43261 tttatctctg attctttagc atataaatat gcaattagtg gttctaatgt aagaggctta
    43321 aattttgctc ctctaacata ttccataaga tagtcatcac aaagtttttc aaagacagta
    43381 aaaccactat ccatgccatt tttacagaca tcaaagtaag aagtagattt aaaacatgat
    43441 gctggagtat ctgaggaaaa agcttctaag aatttttcct tatcaagtga gccacctgaa
    43501 acaaacacat tcataaacat atcaaaatct ttcttcatat ttttgactct tataaaactc
    43561 tttagatttg ttaaatcaca aactttcata acataatcta ttacaaattt gttttggctt
    43621 tctttagcag tttctttcat actggtaaag gttgctttat ctagaacaat atcaaccatc
    43681 tggccatttt gtgtcttatt ataaacatca aatgcctcta atatagctga tgacattatc
    43741 ttaggtaaat cactaaaact acgatttgct aaagattctc taagcttaat aagaggaatt
    43801 gtacctccat caattaaata tttctcacca tctacaccag aaatttcttc tttaatcagc
    43861 acttttaaat tgtgatagtc atttttataa agaaatacat caacaaattt ttcttcagga
    43921 gctagacttt taagaatttc atatgtcttt gataattctt gagtcaaaat attctcaaaa
    43981 ttatgtatat tattatttga tgtatcagca taacctgcct cagctataat tcttaaagag
    44041 tcttcagggc ttttggcttc tgccatttga ataaacattt gtctgttaag aagctgtttt
    44101 tcaagcactc ttattcgtgc aacggcatag ggataagttt tttcttctgc cattttttaa
    44161 cccctcctta attaaacaaa atttctgctg caatttgttc aatatattca tgctctactg
    44221 caattatggc ttcaaatgaa taattgtact caatgtcacc ttttttaact atgaaacctc
    44281 cagtaatatc tctagtttca tcagacactt taatgccttt ttttgatagc acatctttta
    44341 atgttttttt atctttttta gataatacta tctctgaatc atctgtacaa tttgattttt
    44401 caatcatgtt tagtataatc tcttcatatt cattatcttt aagatttaaa agtttgtttt
    44461 tagcttctaa aattacctct tctaaaatct cttgtttttt tgataatatt tgctttttag
    44521 cctccatata agctcctgat atttccttag aagccgcttt ttctgcttct gcctctgcaa
    44581 gctttgtata ggaagccatt tccttttcag ctttttcatt agctgaattt acttttaaat
    44641 ctgcttcact tttagcttta tccaatattt cttgtgcttc ttgtttggca tcagctataa
    44701 ttctgtcaat cattttttgt tcattaccca taggagtgct tcctcctttt catttttttt
    44761 acttatgaat tataatttat aattaaccaa ttgcaattcc attgtaagct aagaaagaaa
    44821 caagtagtcc taaaagagca tatgtttcaa ctattgctgc aaatgttata gctttaccaa
    44881 gttcttcagg tctttttgca actattccaa ctcctgctgc tgctgcttta ccttgtgcta
    44941 tacctgatac taaaccaact aaaccaattg gaagtcctgc cataagaagt tgtaaacctt
    45001 gagctgatgt tggtattgca tctccaccaa taatccctgc ttttgataaa ataaggaaag
    45061 ctatgataaa tccatacaga ccttgtgtac caggaagaag ttgtaaaact agaagttgac
    45121 cgaatttact agggtcttct gttacaacac ctgctgcggc ttgacctgct attgaagtac
    45181 ctttagcaga acccatacct gcaaataatg ctgctatagc agctcctgat attgccaaaa
    45241 attgaccatt tcctaacgcg tttaaaaatt ccatatttac atctcctttt tattaatgct
    45301 tgtatatttt gttttatact taaacggaac aaaaggaact cctccgcctt cataaaactt
    45361 attgaaaaat tctacatact gtaacctact tgtatgaaca tatgcaccta gtgcatttat
    45421 aagaaggttt attgtgtgtc ctacaacacc aattacaact gcaagtatcg gaccagctat
    45481 agctcctaaa aggttgataa cttgtgctat aactcctgtt gttaaacaaa gcgccataat
    45541 tcttgtataa gataatatat cagcaaaata acttgttata ccatagagac ttgaaaatcc
    45601 tttaaaaagc ttaacaggaa tacctttaaa gcttcttcct tgagtaagta caagacctat
    45661 agcacctata attgctaaat attttcctac ttctgaaaat acacctatgt cccctgcaac
    45721 aaaaggtatt ataagtagac atacacctgt tatacacaaa taccaaaaac ctatgtcaaa
    45781 gattgcatct attacctttc cacttcttat taatgtatat gcttttattc ccaaacctac
    45841 atatatatgg ataataccga acagtaacga cattcccata agtgtcataa catcctctaa
    45901 aggattaatt aatgctttta taggaattaa atcccccaaa atacccccga atataagacc
    45961 ccatacagta gttgaaactc cacagatacc aataagttta attaaatttc cttcaccttt
    46021 ttgtatcttt aatttatata caacaaatcc acaaactact gcaattatta acccatatgc
    46081 ggcgtcactt agcatcattc caaagaatac aacaaagaag aaagttaaaa ttgtatttgg
    46141 gtcaatatct tttgtacttg gatagctgta catgttagtt acactttcaa aaggtgttac
    46201 taatttattg ttttcaagca gaattgggaa gccttcttct ttacttcctt cttcagtctg
    46261 aacacaacaa tcaaactttt ctgtaatttc tttaattaat tcatctgccc ttttgcttgg
    46321 taaccaacca ttaagacaga atgttgtttt tgttttgaca agtctctcta taatcttttt
    46381 ttggtctctt tctatagtgt aaaaatcata taggttttca agcatgtgta tactatctgc
    46441 atgtctttta atttcctctg ttttgtcctt agaaacgttt tcctgtctaa ttatcatttc
    46501 attgtatttc ttgatagctt gtaacggtgt accttcttca tttggtaatg aaaccactga
    46561 aaaattaaat tcttttaaaa cttctaaaac atcatcaaaa gtttctttta aagtaattaa
    46621 ataaacatag ttcattaact tgtcagaatt gacaatccca ataacacttt ctggtatttc
    46681 atcttctaat tttactctta aagcatcaat gtttgcgctt atgggcacag ttccaagtat
    46741 agtttttgta tacttagttt ccatattttc aataggaata tcaaagttca cccatggttc
    46801 taacatactt ttattgttgt taagtaagtt tatgttagac cttattgtac ctatctcctt
    46861 gtgcaaattg tttaactcca gagcttcagc ataaacttgc ccttcttttt cactatcaat
    46921 tttgttaaac tctctttttg gtgcaagtag ggattttttt tgtttcacta gtgaagaaac
    46981 aatattaatt gcttggttta catgagacat tttctgctct agcattataa cttcagattc
    47041 ttcactatct tttacaagat aattttttaa ttcctcctcc tcagtaagaa aggcactatc
    47101 atcaatctga acaaacccac ggttcataag tagctttaaa atctggcttt tttgagcttc
    47161 taagccaaca atagatattt tgttcatatt aactattgcc atattatctc actacctttc
    47221 caataaccgc ttcaatagcc ttactttttc tttcttcagc agttttttca attttcagac
    47281 attcactttt agcattagct aagattttat caacctctgc tctactgtcg gtgactgcct
    47341 tctcaataag agtttcttcc ataagctttg cttgtttttt tacatcagca aatatgcttt
    47401 cacatttgtt tacagcatca gctctgatag actctgcatc agtaacagct tttactttga
    47461 tactgtctgc tgtctgctct gcctcaacaa tgctttttat tatttcaaaa gccatccaaa
    47521 tcacctctct taccttttta ctatgtatat aaccaattag atttttttat tctaattaga
    47581 ttactacctc attgttaaag tataaacagc atttttatat aataattaat atttttcaac
    47641 gtttatttct taataaaaca tattttagaa tagtacttgc ctagatttac atcctttttt
    47701 gacttacttt tagactatga catgagtatg gtttttaaat accattattt tcaataatta
    47761 taatttaaag cgatatagtt tgtcaatagc gttattttgt tttaaaatta acgttatgtc
    47821 gacattttaa atttttattt tatttttttt ataattttaa tttaatttat tacatataaa
    47881 agttttttat attctttttc aacctctaac cattgaagtt tattgttttt tttgaatttt
    47941 tagaaatatc tcgcactatt ttatctaact tttataaatc atcaagctat atcgattttt
    48001 gtcaccttat ttttaatcta atttttttat atctagttag aaataaatca atatttttaa
    48061 agattgataa aacttacacc tagttctaat agttttattt taaggcaatg tattaatctt
    48121 aagtagataa tatcattagt tactctatat attcgacaac attataaaaa aatcctcgta
    48181 ccaatcactc caatcttcaa taggatatgc tgctcctcca tttacacttt tcagtagatt
    48241 ggatgtatat tcttctccca tagaaaaaag ttcccctact gtcatatcat aacctctaga
    48301 tgtaacaacc ttacaaaatg aatccataac atcacgttgt tctcttgttt ttataagttc
    48361 ctttctaaat tcatcatcat tcttagcttc ttctaaaatt ttagttaatt tttcattcat
    48421 tatgtatttc tccttttaag tagtctttct gtaaacttca ataagcttta tataaaaagg
    48481 aagccatcct aaataaacta agatgacttc gcttaactgt tagcaacaca tttactagta
    48541 taaaataatt ggtgtacctg gttctatatt ttcatatatt ttctttgcct tagaaaaagg
    48601 tgtatttaca catccatgtg aacctgaaga cttatatata cttccaccaa aagaatttct
    48661 ccaagtagca tcatgaatgc ctatgttccc attaaatgga agccaataac ttacaggtga
    48721 actgtaacct tgaccagtta atgaaacatt tctagcctta taattaagag gatatatacc
    48781 tgatggtgta gcaaatcctc tagctaaatc acctgttaca acgtctgttg atacaagcat
    48841 ttctccattt ttaaagaacc acatatgttg gccagaaaga ctaatctcta catatgtatt
    48901 tccaatatca tctttattac gagatacagc tttttgtatg taaataggtt ctcttgtaac
    48961 atttttacca gcttttacaa catcaactaa tgcttcagct tctttctttt tatctatcaa
    49021 ccaaccataa attccacctg aaattgtaat atctttacct gtggcagttt taaatggtct
    49081 tgagtcacca aaagtactgt attttttact taaacctctt gtatattcta ccatagcatc
    49141 attatcaaaa gttatgtcat aattcttttc tgagtctact tttaaccatt tattaatttc
    49201 agaaccatct aaagtttcct tacggtcact aaaatcatat gtaacgacta caccaacata
    49261 cttatctaat gtcttaatag cttgtttcaa cttttctgaa tcctttgtgt tgtttggtgc
    49321 ttcataaact ttactttcat ccagagaaat agaagtattc ccagaattaa ttgagttttg
    49381 tactaactta taaaaatcat cttttttcac tttgtttcca agtacctctg gtactataac
    49441 ataagcgttt ttagtgctat catacttagg ataagcactc ttaggttcta caacattttt
    49501 actatcaaaa caagataaag cattaaacct tttttctagt aaatctttat tatatgaaag
    49561 agttatcata ttattatact ctttagattt aaatattcca ccaatccatc caatagcgct
    49621 ctgactatct tttatctttt gaactttatc atctggtgta aattttaaat caatatcttt
    49681 tgcttttatt tgttctttct tattgtttct ttcctctaag tttaaagtat aggaattagt
    49741 actagatgct aacaaatcat ttacttgctc aactgttttt cctgaagcct ttacgccatt
    49801 aatagtcgtt ccaaagtaaa aatgatttct aaaaaagatt gccattccta tataagctac
    49861 aaacaaaaca cctactacta tagctatctt aaattttaga tttttttgtc cactttcttg
    49921 ttttacctct tttccatcaa tcataattaa atccttcctt acattgtaat tacctatgta
    49981 ccttattggt ttttaaacaa aaccatgtat gccttatttt atatacccaa attactgtat
    50041 cattatttat atttttaaat atatagttat ttctataaaa ccattttatc ttttagataa
    50101 aatgattatt ataaatcccc cctttcaaaa tcccttaaac acaatctctg ctatattaat
    50161 atattaccat acttttaata atcgtgggac tatctatcta tttttgtaac actaaactac
    50221 tattttaaaa aagaaactaa ttttgtgtta gtttctttat cttaacttat ttttatattg
    50281 aattttagct taacataacg ttgttatata gattctattt aattatttta gtttctatat
    50341 cttttccatc tgcatattct ttaagtaatt ccttagcata tccaaaatat tcttcaatat
    50401 cagattcttg actaaaagaa aatatacaaa ttaatatttc atttgcatct tctgttatca
    50461 ttgctctttc agaatcacta gttggactcc caaatttacc cactgaatca gacaatatag
    50521 gaagattttc tatatttatt aattctttcc caataccctt atactgttct ccttcatctc
    50581 ctacagtaaa acatactggt gaatgtaatt tgcttacatt atatgtacct actggatata
    50641 atgattttat tgatattaaa ttgtttattt ctactatatt atttattgta taaagaccct
    50701 tcccttgaat aattcttcta accaatgctt ctgaagatgt tctatatcta cttggatttt
    50761 ttccaagctc tttataagca tttcttgcat ctttaatttt atctagtttc gtaatgtctt
    50821 caacttttag actttgattt atagtatcac aaaactcatt tatttcatta attaattttt
    50881 ctgagctttt atttactgct acttttgctt gaatgcaacc cagcttagca ttaggccatc
    50941 tttccttaag tttgtcatca atacttatat ctatcatact taaacaactc ctatacacta
    51001 aatttttatt aaagttttta tcatctatac attatagtac tattcttttg ttaataacat
    51061 gtttattagc aaaataaatt tatttttaat ataattttta taaaatacaa ttattttttg
    51121 ctttatatta gacaatacat tgataaaata aaaaaacact aattatttag caatgattta
    51181 ttaaaatcaa gcattcataa tagtgcttta tataaaaatc aaattttgtt ttaaagtaaa
    51241 tctaaaaaat tcttagctgg cattggtcgt gcaaaataaa atccttgaac taaatcacat
    51301 ccaaattgtt tcattaactc agcttgttct ttactctcaa caccttctat aattacaact
    51361 aaatctaggg attttgctag agacactatt gattttgcta tattgcgact tctctcatca
    51421 tgttcaatgc caccaagaaa agacttatct agcttcaata tatcaattgg catatctctt
    51481 aaacaactaa tagaagaata tcctgtacca aagtcatcca tagaaataga aaatccatac
    51541 gtcctcaact catttaaaac attctttaaa atatttaact cattaatagc cacagtttct
    51601 gttatctcta tttcaatgaa atctgaactt aaattataca tttttattgt tttattgata
    51661 aattttacaa tatctggttg atacaactcg accctagata aatttactga aactggaact
    51721 atctttttac cttgcttttt ccattcatat aaatcattgc aaaccctttc aaatacaaat
    51781 ctcccaattt ttaaaatcaa cttacttttc tctgctattg gaataaatac tgcgggactt
    51841 ataaaaccat gttctggatg attccatctt attagtgctt cactccctat catttctcca
    51901 gttacaagtg aaaacttagg ttgataatac acttcaaatt gattttttac caatgctatt
    51961 tttatatcat ctaaaatcat tgattcctca ctaagcttat tcctaacatc ttcattataa
    52021 atagcataat ttatattttt acctttagca acagacctag ccatatttgc tttatttaca
    52081 gccttttgaa tatctacttc accttcttca acaaaataaa tacccacaca cagagaaatt
    52141 tcaaagacta tactcaaatt actttcaata ttacttcgta tattatcaag ttttcttata
    52201 attttatttc ttccattttt ataatcacag aaaattgcaa aataatcact tgaaagtcgt
    52261 gcatatacct caccttctgt taattcttct tttaaagctt ttgctattgt aattaataaa
    52321 ttgtcaccaa attcatatcc aaaagtatca ttaatcatct taaagttatt aatatcaaaa
    52381 tatactataa tataatttaa agatggttta tctaaaagat acttactaca ttctctataa
    52441 aatttatttt gatttcctat atatgtaact ttatcttcat aagccaaact taatatttct
    52501 ttttcattag atttttttat ataaattata taaaaaataa ttgcaataaa tattaataca
    52561 atagataaca ctgcatatac agctctgttg attatttgtt ttgaattact aaatacaaca
    52621 gtttctggaa ttgaaaaaat taaattccag tcttttatat aattattttc actattccca
    52681 ttatccatag tggcatatcc taaatatctt ctttcttcca acatatttaa tacagttgca
    52741 cctgttttat tttcttgcaa ttcttttttt aatctattta cttcttgaat atcattatcc
    52801 tgttttaaca atttataaat attttttgat aggctatccc cttgtggatg aaggataatt
    52861 gtaccattat tttttacaac ataagatata ctattatttt cataaaaaga tatattaata
    52921 agtttcatca gagtattgat attgtaagta caatataaaa ctccaactac tttatcatta
    52981 tttaataatg gtactgaaat agcaatcttc tttatagact tatttacttc atcaacatat
    53041 ggacttgaaa catacttctt acctttaatt gagtttttga aaaattctct atctttcact
    53101 gaaaacttat cacctttggt attttcagca ttaccattta tatcaactat tgccatagtg
    53161 taaaattttt gattttccat ttcatctaaa agatttttca ttttttcctc attaggtata
    53221 tctggatttg aagcataata gttagaaaaa atatttaaaa catctaaatc tttttcaatt
    53281 tgtctttgtg ctagttgaga gccttgtact gcaacttctt ttatatgtat ttttgcctct
    53341 gacataagaa gatgttttgt atcttctata tagatatacc ccattgtcaa aaataatgat
    53401 gttaaaaaaa gaattgtaat taatgtaaaa cttttatttc tccctgtcat tcgactcctc
    53461 ccctaattag tcaatacttc atatagataa tatatccttt ttataccaat tcatcattta
    53521 tattgtatat aactattctt aaatgttaca cataaaatca acataataac cataaaaaca
    53581 ttcttttatt attataataa cactatttaa ttgaatttta aattaaagaa taaaaactat
    53641 ccattttctc aaacaaaaaa actcttatac aataaaactt tgttttatgt ataagagttt
    53701 ttattttatc tattttatag caaacttatc ttccataata tgaatttaaa tacatatctt
    53761 ttatttcatt cataagtgga tatcttggat ttgctcctgt acattggtca tcaaatgctt
    53821 gaattaccat ttcatctatt gaatccataa acttagattc ttcaacgcca aactctttta
    53881 tagatttagg aataccaact ttaagtttta aatcttcaat agctaccaat aaactttgga
    53941 atttctcttc atcagaattt ccttttaatc ctaaaaatga agctatttca gcatatctct
    54001 ttaatgcttc tggatattta tattgagaga atgctcccat tttctttggt gcatctgaag
    54061 aattaaattt cataacttct gttatcaaaa gagcatttgc aacaccatgt ggtacatggt
    54121 ggaaagcacc taatttatga gccatagagt gacaaacacc caaaaatgca tttgcaaaag
    54181 ccatacctgc cattgtagaa gcatttgcca ttttttctct agcttctggg tcttttgcac
    54241 cattatcata tgcacgtgga agatattcaa atatactctt aatagcttgt aacgctaatc
    54301 catttgtata atcggttgca agcatagata catatgcttc taatgcatga gttaaagcat
    54361 ctataccaga agcagatgtt aagctttttg gcatattcat catcatatca gaatcaacta
    54421 tagccatatt tggcatcagt tcataatctg ctaatggata ttttactcct gtatcttggt
    54481 cagttataac agcaaatggt gttacttctg aaccagtacc tgctgatgtt ggtatagcta
    54541 caaaattagc tttttcaccc attttaggga atgtatatac cctttttctt atatccataa
    54601 atctcatagc taggtcttgg aaatctacat ctggatgctc atacaatgtc cacattattt
    54661 ttcctgcatc cattgcactt cctccaccta tagatattat tacatctgga ttaaattctc
    54721 tcatagcttt agcgcctatc ttagcacatt ccaaagttgg gtctggttct acttcaaaga
    54781 atgtagtgtg cttaatattc atttcatcta ataaatcagt aactgcttta gtatatccat
    54841 tattgtaaag gaatgtatct gttacaataa aagctctctt cttattcatt acatctttaa
    54901 gttcttttaa tgctactcct aaacaacctt ttttgaaata aactttttct ggtgctctaa
    54961 accaaagcat attttctctc ctctcagcta ctgttttaat attaagtaaa tgcttaactc
    55021 ctacattttc agatactgaa tttccacccc aagacccaca tcctaaagta agagaaggag
    55081 ctagtttaaa attatataag tcccctatac caccttgaga agaaggagta ttaattaaaa
    55141 ttctacaagt tttcatggct gaagtaaact tatcaagttt ttctctttga tttacatcat
    55201 caatatataa tgaagatgta tgcccaaatc caccatcttc tactaatttt tctgcttttc
    55261 taactgcatc atcaaaatca cttgccttgt acattgcaag tactggtgaa agtttctcat
    55321 gagcaaaagc ttcttctatt tcaactgatt ctacttcacc tattaaaacc ttagtatcta
    55381 ctgggacttc aaagcctgca agttttgcta tagtacaagc tgtttgccca actattttag
    55441 aatttaatcc tccatttact aaaattatat ttcttatttt ttctgtttca tctttatcta
    55501 ataaataagc accacgctct ttaaattctt ttttgacttc attgtatata ttttctaata
    55561 ctataaccga ttgttcagaa gcacatatca taccattgtc aaaagtctta gatacaagaa
    55621 ttgagtttac agcagttttt atatctgcac tatcatcaat tattgctgga gtattacctg
    55681 caccaactcc aatagctggt tttccagatg aatacgctga tttaaccatt ccaggacctc
    55741 ctgtagcaag ggtcaaatcc acttctttca taacagttgt agttaattct aaagatggct
    55801 catctatcca tcctattata ccttcaggag ctccagctaa aacagcagcc tcaagaacaa
    55861 cttttgcagc ctctatagta gaattttttg ctcttggatg tggagagaaa attattccat
    55921 ttctagtttt taaagctaaa agtgctttaa agatagcagt agaagttgga ttagttgtag
    55981 gtacaactgc tgcaataaca cctattggct cagcaatttt agtcatacca aatgcttcgt
    56041 ctttctctat aacaccacaa gttttagttt ctttatatgc attatatata tactctgagg
    56101 cataatgatt ctttataacc ttatcttcag caattcccat accagtttct ttttgtgcca
    56161 ttatagctag aggaactctt tgcttattag ctgccaaaga tgctgctaaa aaaattttat
    56221 ctacctgctc ttgactatat gtagcaaata ttttttgagc ttctctgatt tttgctagtt
    56281 ttttaactaa gctttcaacg ttatttacag tatctaaacc aactgacata acttcatttt
    56341 cttttttatt ttctattatt acttgttctt tatgagccat tttaacaacc tcctgagata
    56401 gttttttatt tatcatgtta atttattaac attatagcat ttactttttc tattttcaag
    56461 ttattttttt aacattttat tttttatcta atataacacc atttctacta ataatatcta
    56521 gctttacaaa tacttaattt aactagatat cactttattt tttacgcaaa tcactaatga
    56581 aatcatctaa aaacttaagg ataacgttat ttttttaacg tttatatttt tgtatttttt
    56641 acaaataaaa ctttataaaa agaattttta atatgatact ctatcaagtt taaaaataaa
    56701 aatacttgaa aatgaaaata aaaacttaat taacaagtta aagtaaatat agttaaatgt
    56761 acaaacattt acaacatata gtataattaa aaaaatatat attcatgatt tttatatact
    56821 atgaaataaa atatatttaa tattatatag ataaatttga agtttataag aaggaggata
    56881 agcatgaaaa aattaaaaac aattagcatt ttttctttga ttataagtgt aattttaacg
    56941 attggaggta ttggaatagt aacttattat gtagataatt tgtttattag aggactatcg
    57001 gtatttgttt taattatgtc ctcttctttt gtatcaacaa cagttagatt gatatttgaa
    57061 gagtcaaaac gatataaatt ctaatttaaa aattggatta agtaaataat tttaatatac
    57121 caaaaattac ggagattagc tcaaaataga ctttttagtc catgaggcat ttttttgtat
    57181 gaaattaaat atattttcat catttcaaca agaaaaagag gcttctctct attttgagac
    57241 agcctctttg ctagtattgt atctaataca taatattata agaaccaatt ctattgatgt
    57301 ggacttttta taacaggctg tagctgtttg ttctctagag caagttctat agttggaatt
    57361 attagctcag tatgtgcaat catagaatta ggctttgctt tgcaattatc ttgaccaaaa
    57421 ggtacaaaat atatattttt agaattaagg agaatgccaa tatttttgaa attaaagctt
    57481 agagcatcat tcgttgatat tgatattact agtggtttat cattacgaag atgacctttt
    57541 gctgccatta atactggtga atctgtaata ccatttgcta attttgcagc agtatttcca
    57601 gtacaaggag ctattattat aatatcagca attcctttag gtccaaatgg ctctgcctct
    57661 tcaatcgtaa ctataggttt atttcctgta agttcatatg cttttttcat aaactcttca
    57721 gaatttccaa atctacaatc gatattttgt gatacatctg aaaatatagt gtgtacatta
    57781 gctccttctt taaccaaatt ctctaactct ataaatattt tatcataagt acaaaacgaa
    57841 ccagtaaatc ctactccaat tgtaagtcct tcaagtctca tttctaatcc cttctttcat
    57901 ttataatatt ttctatagcg ttaacaagaa tttcaccaga tgtctttggt gaatatttac
    57961 caggaagccc aaggcaaaga gtcgcattaa tccctgcttc tttaacaaca gaataatcta
    58021 ctcctccagg agaagaagct atatctataa tagttacttc ttgtgatact ttttctaacc
    58081 tttctttcgt taaaatacac tctggtatgg tgttaaaaat ataatcaaat tgtaaaagtt
    58141 tttcatcaag ttgacttaaa gaaatactgg aatatccaaa tgcattagcc gtacttcttg
    58201 catcattatt tcttgcgcca acacatacat ttgcatccaa agtgtataat ttttttgcaa
    58261 gtatttgtgc acatcttcca taacctaata ctaaacagtt actttgatgt atattgatta
    58321 tacttctttt aatagcttct gctatagccc cttcagctgt agcaactgca tttaaaatag
    58381 caacatcatt cattttcata aaatcataaa tctgaataga gtgttgctcg caaaatttac
    58441 aaactttagt tggtatgtta cctccaaata atatttgatt aggagataaa ttaattagca
    58501 agttatcaat agtagcatca agacaatcat ccgtattttc aatattaact tgattctttg
    58561 taaatggaat tggacataaa ataatggaac ttttggatag tgcttcagct agtgaagttg
    58621 attttccaac gattccattt ataatttcat ttgatatccc ataagtgact acagaatacc
    58681 ctttattaat tagttttttt accatgtaca cttgtcgcag gtctccccca ataacagtta
    58741 tatcgtattg atttgacata ttgtaagcct cctttactat atacaatatg tttttatcaa
    58801 tacattggtt cactaaaatt actaaatatt atacttataa catttttaat aatgctaatc
    58861 tatctatctt ttcagaagag gtatatggaa atgaatttaa aaagataatt ttctttggga
    58921 tttcattttt cattagatta tctttcattt taatcaacaa atctttcttc gtaattttgt
    58981 ctatagttat tacaaataat acaatttgat ttcctcttat agtgtctgag tacggcaata
    59041 caattgcatc ttcaatttga ggaatttttt taacttcatt ttcaatctta gtagaactaa
    59101 ctttaaatcc tccaatattt aaaatgtcat cacttcttcc ttcaaatatt aagtatccat
    59161 cattatcata atatccaata tcattgacag aataaggttt ggttgcatta tatactgcat
    59221 attctgtatt cacaaaaatt tttccttctc taatatatat atctattcct ggaaatggtc
    59281 tgcctacact tagaggtttt tcaattagtt catcatagca taaatatgta atataattta
    59341 attcacttgc cccatagtat aaaataattt cagactttgg catatatttt tttagatttc
    59401 ttgcagtatc ttcaaataat aattgagacc ctgtaaaaat acttacaact ttgagtactg
    59461 gttcttttaa gtgtttaacc aaaagttgaa gttttgtagg tataaggtat atgttagtta
    59521 cattatattg ttttattgtc cttatccatg atttacaatt aagacctgaa cttattacaa
    59581 tactacctcc ttcatataat actgacatta tagaatttag attccctgta aaactaagtg
    59641 ttccattaac aaacaagatt gattccccag agatattaaa aataccattt tgtataggaa
    59701 aaaatccagc ccaactctca tatgttctat ataatacctt tggaacactt gtagaacctg
    59761 aagataaagc tcccatacaa atacttttat ctaaataatt tataagcttc ttatattgat
    59821 acatatatat attaaattta ggattaaaaa tagaaaaatt aacttttttt gctacttcat
    59881 tattgttatc atcatataaa tcaataacgt ccatagattc atcagatata atgattgaaa
    59941 tattattttt taataaaata tcatctaata cttttttaga aagattataa tgacaaataa
    60001 taggaatatt ttttgaataa ttaatagcaa aaaaactaat caactgaaac attatatttt
    60061 tagaatatat taaaattggg atattttcac ctaaagaaat ttgttttcct agttcctcac
    60121 tataactcaa tagattttca taagtatatt tttctccatc tataattaaa aaatttttat
    60181 ttttatgcct ctcttttttt attcttaaaa gttcataata gttcataatc tacacccttt
    60241 caagcagtaa agctgaacct agaccaccag ctgcagctat agagcaaatt ccatatctac
    60301 ccttagtctc ttctaatgct tttaaaagat gtaatgcaat aattgcacct gaagcaccat
    60361 atggatgtcc atacgctaaa gctccaccaa atatattata tctatctatt aactctggat
    60421 actttctttg aaacaacaca tctataactg caaatgcttc attaaattca acagcagata
    60481 catctaaata attaaggctt tctatctcta aaagtttatc cattgcttgt atcgctgatg
    60541 ttggacttaa ggttgcatct gttcctatcg tgcatgtgtt aataattttt gctttaggct
    60601 tcttttttac atgttctaaa tacttcttag aacatattat aataaatgaa gctccatcat
    60661 taataagaca tgaatttgct gcatttgtaa tagtttcttt tcctaaaatt gatggcatcc
    60721 tatctaataa cctttgactc atcttatcac gtataccttc atcataggta ctattattta
    60781 taggagatat aatatcttca agtatttttt cctctcttgc ttcttttgct cttttatgac
    60841 tttcctttac ccaaaaatcc aagtctgctt tctcaatttg atataactct gctactcttt
    60901 ccgcaccttc gagcatacta ttttggctat tatcatcagg agaaaattga gcaactgtat
    60961 aatttggatt atttgtatta tatcgcttat cattcttatg atatgtgcgc attggttgta
    61021 gagaactact ttcaaaacca cctgcaataa ttaaatcaca ctgaccagat ttaacctttg
    61081 aaaaagctat gtctatactc atcatagcag aagcacactg catatccaca gtaaaagcag
    61141 gtacttcatt tgacactcct gctgttaaag tcattaatct agctatattc cctcctgtcc
    61201 caactgcatt tccacatata atctcatcaa ttttgtcaat ttcatacttt ttaattaaat
    61261 cttttaaaac acttgctcct agtaattcag gttgaacaaa ttgaaaaatt ccatttttta
    61321 gacctatatg acttctcaat cctcctaata taaaaacttc cttcatacat tacacccttc
    61381 cttatattat agatttatca tagatttctt ctgagtacat tgttcagttt agtgcctaaa
    61441 aaagatgcaa taactgactt tattgtatct ccaattaaaa atggtactac tgctgcaaaa
    61501 agtgctgctt ctactgtcat ttgattaaaa tagcacataa atactgttcc cataaaatat
    61561 ataataggca ttccaacaaa aattgttatt agtatatatc tcttaatatc attgtttcgt
    61621 ccttttaata aactaataat tagtgctgca aacaaaaacc caaaataaaa accacctgtt
    61681 gggcttaaca actttccaat accagatgta cctccaccaa atactggaat cccaattaaa
    61741 cctatcatta tatatacacc aactgtacta aatgcttgtc ttggtgttaa aatcaaagct
    61801 attaaattta tcattattgt ttgtgctgtt actcctgctg gagtaaatgg caatggtata
    61861 tatatgtaag atgatataca caataatgct acacatattg acattttagt taaatcttga
    61921 atatttactt tagtattttt catttttata attcccttca tatgtcttat ttcatttagt
    61981 ttatatgtac atatacaaag cttctattaa agctttgttt tagtataaaa taaagacgtt
    62041 tttttgtcaa ctattataag tatttaggtt tacatttaat ttataagtaa actttatact
    62101 gttactttat actttaatag tcatttataa aactttgctt aaaaacagct ctatttagac
    62161 tatacttgta aattataata tgatatattt ttatataaga ttttatttta tataaaaaat
    62221 agtaacaaat agtttataca caagatattt aaaaggaagt gatgatatga aagttaatga
    62281 aaataatata aataatatag atgaagagtt agatgaactt agtaggaaag tttacttaga
    62341 gtcaccagat ttttggataa gtatttctga caaaataata gataaagtat ttgatgaaat
    62401 gttattattt tttgcagtta aatataacta tttcaatata gtatgctttg ctattgaaaa
    62461 caattatctg gatttaaaca tgccttcaaa aaacaaaaaa tacactaata taatggagca
    62521 tttgttagat acatcaaaac agaatgaaga taaaaaaatt tataattatc ttctaagctt
    62581 aaataaaggt aataacctag atgaaagacc aattttagat gaattaaact gtaatattag
    62641 tagtgatact tttgaaaaaa aagatatata tcttccaaag tacttatgtc caagttgtaa
    62701 ttctaatata tttgatacag gttataaagt atcaaatgac ataacatata aattttcttc
    62761 taaagaagct gaacctattg aaatgtgtag tgaagtttct tctatcagat gttgtaattg
    62821 tgatgaatta ttagaagata ttacacttga taaactatat aacctatgca aaattcaaaa
    62881 ctgtaataat tgtggttcta atttaactaa ggtaggaatt attgcaaaga aaaaaatgaa
    62941 ctttgatgag aatactgaaa aatttaaaga tgtctcaaca tcttactgtt gtggaaattg
    63001 tgactctgaa ataaacttat ctcaaagaga acattttaag atttaaatat ttataggcta
    63061 aagtaataag attacattat tagatactgt ataagttttt taaatctgta aaaataaata
    63121 cacttatacg aattaaaatt gctatgaaac tagttcttga tgaactaatt tcacggcaat
    63181 tttctataat ctaataatta ttaaatttta acaaaccttt attagcattc cataattatt
    63241 taaaattctt tcaaataccc tatagtttat aggtgaaagt atctttaata ttatatcaaa
    63301 cttattatct ttaaatagta aatttgttaa atctgaaata caccatacaa ttttattttc
    63361 ctcttttgta gctatatcaa ttctgattaa cttacatcta taataaatat ctttatcttc
    63421 atatagtcta ttttaaaaat tactcttaaa aaatcaaatg gcaaataaat taattatcct
    63481 tttaatagaa tgtaatcata ttatttacta tattccatta tgtactcttt aaatcctgaa
    63541 tcttcattta cttgttcttt tactatatta aaaccttttt tattataaaa cacaactgct
    63601 tttttattat ctttatatac tgctaagctt agacttttat attttttagt tgcataatct
    63661 aaaagtttac ctccgatacc tagattttgg tatttgggct ttataaataa agctcctata
    63721 aagcttttat ctattatgct tataaatcct tttatttcat ctccatcatc atatacaaat
    63781 gtatctgata taggtatata ttcgttttta acagtattat agttattttg ccagtattct
    63841 ttacttataa agtcatgtgc tttgattgta cttttttccc atatttccat gattttattt
    63901 atgtctttat tgtttaattt ctttatcata aattttattt cacctcattt ttgtattgat
    63961 tttataatgt ttataggtaa gtgtatttta tttagatatg atttagttaa tataaggtgg
    64021 atgttttagt atatgctatt gttgattcta caattttata tactgcttta ttaatataaa
    64081 ataagtttct aaatactcgt tgatattgct aatattctac ttatctaccc ttagttgata
    64141 taaaacctga cactgtgcct tgtgtgagtc ttttctttat cctatttaca taccacttag
    64201 ttaatataaa acgttgttag ataaatcata tgctttagtt gctttagatt tacataccac
    64261 ttagttaata taaaacactt cgaaattgca gttttcagca tgttattgcg caatttacat
    64321 accacttagt taatataaaa caaattcgag gtcttgattt tgaagttttt ggttatgcat
    64381 ttacatacca cttagttaat ataaaacggt ttctaccaat caaatcacgc ataattatag
    64441 aatttacata ccacttagtt aatataaaac aatcattttg tatgattgtt ccattttttt
    64501 tgaaaacatt tacataccac ttagttaata taaaacctct gtgactccat atttttttgc
    64561 aatatataat tcatttacat accacttagt taatataaaa ccatttgtaa atctttatga
    64621 ttatgtaata tattcataat ttacatacca cttagttaat ataaaacttt ttgaatgttg
    64681 aagattttgt taatgcaggg aaaatttaca taccacttag ttaatataaa accccaaaat
    64741 aggtataatt gaatacattg aaaatacttc aatcaagcaa ttataattca ataaaaacat
    64801 caaaatttgc agtgagcgag cagtagtgca attgataaca gttatcatac accttcaatc
    64861 ccttatattc caactgttaa cacctatttt agcataaata tcgctcactg caaacctata
    64921 taaacatttc atcagaatac ttatcaatcc cataacattt ctttttaatt gaattaggat
    64981 tttttatctc ataaacatag attgaatcct cgctattatc aataatattt tctatttcag
    65041 aaatacattt atgtaacttt ccttcagtaa tattgccttc aaaaacagaa ttttgcgtcc
    65101 aagtcaaata ttttctaagt atccttctaa ttctatttaa cgaccttgct tcaacaatat
    65161 cataagtaac aataacaaac atacttacca ccacaccttt aaaactttgt acctttcatc
    65221 atttataaaa tgtttaatta atttataaca ctctaacctt ataaacattc tatatgaaac
    65281 ttttctattt agatttctat gttttatagt tgtctgcatc ttattttcaa attcttgcaa
    65341 aaatttcttc tttccttttt cacttaaata acaaattttg tcttgatatt caaaatcatt
    65401 cttattaatt cttttattat taatcaggct aaaaattatt gtgtcaacta taattggctt
    65461 aaaaatttct gcaatatcta aacttaaaga aaatctcttt gttgatggtt catgtaaaaa
    65521 gcttattgta gggtcaagtt gtgtcttata tatctcactt aaaacattcg tatacattat
    65581 gctatttcca aaagacataa gagcatttac tgggtctttg ggaggtcttt tttctctttt
    65641 ataaaattca aaatcatctt ttaatatttg attaaatgat ttatagtatg tttttcttat
    65701 tctgccttct ttacccataa gttctgatat ttctttgaca tcattcaaat catttagttc
    65761 atcctttata gtatcaatta aactttcatc aactttgtaa tatctcatat ttcttaaaat
    65821 atggtatgat gcactttcca caaaggattt tgctaagtat aatctttcat ttttatctaa
    65881 atagcaggct gattgacata ctaaactgaa tcctgataca tttttcttcc ttggataata
    65941 tgtacctgaa taatatccat agtaattgta gaaatgaagc atcaccccat atttacttat
    66001 gtaatttata agttttgtgt ttaaatctac ttctccatat atatgaatat catcaacttg
    66061 ttctactggt aatatttttt tctcaccttc taaattgtaa tagtaaatcg tattttcttt
    66121 cctttttata tccccattac ttataatata atagtcttta tacattgtta ctcctccttc
    66181 acaaaacaaa attcataata agcacatttt gtacaataat gttttttctc aattttggga
    66241 ggagataact acatatttat ttcatttata tttataagtg tgttttcaat aattctttct
    66301 ttttcttctg tcaatatcaa ttcttcttgt ttcttttcct taacataatt tatagttcct
    66361 tttttctcta tacccatact attctttaaa tagtataagt aatagtataa ctgcatttca
    66421 tctgcttctt tcatctttga acttattttt acttctttta catactcatc ctttattata
    66481 tctagcttca agatatcatc aatcaatatt tctttatttt tcattctttt atatgaatct
    66541 tcatgtacta tcttcccaga caatactcta ctactatttt gttccatggt tattccttta
    66601 gaaaatagcc atagttttct tttacataca taataataat ttatttttac accttgaact
    66661 tttaatactt ctaaatctat tggcacaaaa tcaccttctt tagtaaattt tagccacatt
    66721 gttaatataa aaatcaaata aattggtcta tttcattact tataagcaca cctttaccaa
    66781 atatctgttt tgtgtgctta ttttcgtgta tatcatattt atataaaagt atttttaaat
    66841 cttcaagacc tttcacctgt atgtcaatta cattttgttt agctttatat attggtaaat
    66901 ttacagtttt tttaattatc tctcttcttg ctttttttct cttagacttt attttattta
    66961 tcaattgtct atcatcatta ctatatgcat ttataagctc ttgtcccaac tcttcataat
    67021 ctttgattaa agtttcttca attttattat atatatcctc tggaattact gtatatcctt
    67081 caatatttct aagtatattt tgtgcatctt tagaacctaa actatatggc gttatagtat
    67141 ctaaaatatt taaagcactg gtaaatctct tttcaaaagc tgtaccttct agactttctt
    67201 tagagtatag tatcttaacc atttctacct tatatttttc tttcatcttc acacattctt
    67261 ttccatttat aaaagttttc agtagctcaa gtcctttttc tacaatatcc ttatcataaa
    67321 tactacctat tcctgtagct ttttctgtat atataaatat atttgggcta ttttcttcat
    67381 actcacgact tctataacat ctaccaaatc gttgaaatag actgtcaagt gttgaatttt
    67441 ctgtatgaag ctcatcaaaa tcaatatcaa gggatgcttc cactaattgt gtagtaatcc
    67501 aaataccatt actatcacta tctgcaaatt cttttatata tttttctaat tttgctctat
    67561 cttcttgtat atacatagaa tgtaaaagat ttaagttgac atctattcct tttggtttaa
    67621 ctatttcttc tattaactca tatttttcta cagcactttt aactgtattt actattacaa
    67681 gaactttttt attcattcca ctttgtatta ttttacctaa gttttcatct attgaatttt
    67741 ctacaataga cacacagtgt cttatttttt ctgtgttaca tgtcaagtca gctaagttac
    67801 tattcattac acctcttttt tttaattcat ctatatatat ggttggcata gtagctgtca
    67861 ttatcataaa tctgccacct atcttatgta tcatttctat accttttacc aatacagctg
    67921 ctatttctgg tgaatatgct tgtatctcat ctattactac ttttgaatat gctaatgttg
    67981 agtacacttt ttcatagcct ctatacaaaa aaggaaattt aaatatttgg tctattgtgg
    68041 aaaatgtcag tttacaagat aataactttg ctaaatctac aatctcactt gaattttctt
    68101 gattactttc ttctagataa tctattgctg ttgaatgtaa caaacctaag aatgtatcat
    68161 ttgattctcc aactccaact atattttttg ctctatcaaa taatgcattt atacttactc
    68221 ttaatggaag tgtaaaaaat gccttgtctt tatctatcca aattaaggca gtttctgttt
    68281 ttcccattcc tgtagatgca atcagtatta tattcttatt tctattagat ttagcaaatg
    68341 attgagcctc tctcaaacta ccaaactctt tcattaaata attttctgtc tgttctccta
    68401 tatttataac attattgcat tccacaactt catgagcaga agcactatgg tctagtctat
    68461 gtagtattcc ttttaacata atatataaat tatagtactt atgattttta tctattcttt
    68521 tttctacact ttgtagatat actttactca atctttctgt ttttattgga tatctaactt
    68581 taaattcatg ctgtagttca taaactttat ttattaaatc ttcatctaat attttttgta
    68641 ttaaattttt aaaatcttta tctataaaga tatctctttc atgatgatat acaataactt
    68701 gatttaatac tgctctaagt tctttatttt ttttcctgtc tatataacta taatcaataa
    68761 atgcaggaga aagataatta tggcctacat tattttctaa atgagttact attttaggtt
    68821 catttatttt agtatccatt ctgcttttta ttaactcttg aaacggtgaa aatgcctttc
    68881 caatatcatg aaattctata acaaagtcaa gtaattgcca aaatatctcc tcttctagaa
    68941 aatctaagct atttatattt tttccataac tttctcttaa tacattcatt tgttttaaaa
    69001 gttcatcagt atgctctcta agtgtttcca ctggattaga tttagcatat aacatactct
    69061 ccctcctaat ttatattatt aaaatataat aaatctcctt cattatctaa taatatatct
    69121 ccaattgata tagtatttcc atcctcaaca taataactat ctaccttatt ccaaaccctt
    69181 tttttatctt ccacagcatt attatcatag taattattga gcctataact tataccatct
    69241 atatctgtat cttgtaaact tgtttttggt atatatatag gcattcttat attacattct
    69301 gataacttat aattttcata atcatctaat tgtatatcct catctacttc aaatttattg
    69361 acttctacaa atctaatatc attaattctt actaaatctt cttttctacc taatgataaa
    69421 tgctcgtcat aatttaataa actatcatat atttcttcca ataaatcaaa atccccacct
    69481 atatgaatta tcaaatttac attcaatagc atatgactat tcattggcat agatgtaata
    69541 ctatcttttt tataaaaata cgttgtctgg taattattaa atatactttc atatgttccc
    69601 tgtacactta tattaaacgg tatatattct gtagcattta atactttgtg aattaatcca
    69661 tttattgtag aatatggagg cagtggatat gtctctgtaa tcttcatagc aaatggtttt
    69721 ttatagcatg cagtttcttg aaataaatct aatttcaaaa ccttcatatt aattcacccc
    69781 ataatattcc tttacttctt taactagttg tccaaaaaat ttatctacac ttaaaaaatt
    69841 atcttcaaac aatcccttaa attcttcttt atttataaat accccatcta ccattccaac
    69901 ataggtaaat tcttttaaat cttttcctaa aaaagtacct tgaattactt cttctatagc
    69961 ttgcttattt attttaaatc catttttatc tccttttaat ttaattctac ccaagaaaaa
    70021 tggatttgct atttcatata ctcctcctac tacaaataga ggagataagt tttcttgtct
    70081 acctctaata tttctattca atacttttat tatttctaaa aattctacta ctcttctaca
    70141 tttctcttta ttatcaagtt ctatatctcc atccttacct attttagata aatctatagt
    70201 aaccgtatat gtatagtaac ttaaatgttg ctctatgttg gcaagattag ggtgttctcc
    70261 tattctatct gcaaatcctt tattatttaa aaaatccata tcacttctat atggctcaag
    70321 agaaatcgca ttacttaatc ttacagtagc ttctctagtc aaagaacctc cttttttatc
    70381 tttctcatct tttttatttg ttttcatata tccaaataaa tccatttctt ctgattctct
    70441 tatacttata ttatctttaa attgaatagt acctttttct ttatcgacaa cctgtaaatt
    70501 ccaattaaac aattctgctg ctaatcgtac tatgtcatat cttaaacact ggcgagatgc
    70561 aaatgtatac atatttccat cagctctact taattttttt aattctgata tattgcctat
    70621 cccttcacca tagtttaaac tttgagcctg tgctattact gtaaatgtta atcctctttt
    70681 catcttattt ttcctccttt tcgtttggta gtttatcttt tccttcatat tttccagaaa
    70741 ttaatccaga tataaaagca tgacctatag attcaaagtc taaatctttt tcaatttcta
    70801 tatctaaaat aaatgctgga atctgttttt cagctgacat aaaaactctt ataattgtat
    70861 ccataaaatc acttttattt ccgactttaa ctgaatttaa aagtttatag cttactccat
    70921 ctattttatt tttagaattt ttattaacaa aatagtcatg tatatcacaa cctaaataat
    70981 aaattatttt cagcttttca tcattcttct ccaaattttt actatccatt ttatataccc
    71041 cctttttgta gctatttatt aatactctta attggactac tctaaaacaa tctattcctg
    71101 atatatttga tttgttgttg ctttccatat catttttaac tttatttctt aaaatgttat
    71161 tagttagatg cttcaagtcc ctatttttca agagtaaatc tagtacattt gatttaagct
    71221 tgtaatcata gatactttgt atttttttat ttgcatactt gtctgtaaaa aattttgcta
    71281 aataagttgg aatattaaaa taatttattt tacatttttt agaatctata cttgctttaa
    71341 attccacaaa aagtatatta cgaagttgcc attcactttt taatgtattt tcttctacta
    71401 tactttttat aagctgatta aaaggatttt catctttgga atctgaagac tcactttttt
    71461 gagcttttaa actattattt ctttcaaaaa gctcatttat agaagtatcc atgttaacaa
    71521 ataaataaaa ctcattttct tcattaatta aataattctt tcttgtataa gtagcccctg
    71581 ctggagtaca gaacaatatt agcttacaaa catcacatat tgatgataca tactcctgat
    71641 tccaaaacat attcctagca ttattggtgc ttactccaag tggagcaaaa ttactttctg
    71701 agtattcatc taatattccc ttatataaac cacacatttc acatacttct aaactatcca
    71761 tatactcttt tatatcttct atgcttttat ttttctttat aaagttttta tttatttcct
    71821 tcataatttt ttctatagta tttatactag acttactaac ttttttttca tttatatcct
    71881 tagctatact atttaatcta tcatttaaat agtttttcaa cttatcatag tcattctctt
    71941 ctaataaatc ttctaactct ccaaaatata taatttgtct taaataatca ttaaacatta
    72001 cctgttttaa tccatctaaa tctaatttcg ccttagcaac attaaaaaaa ctaacttgtc
    72061 caaaataatt atcttgaact acatatttat aaagatttgc tgtaagcctg tcatttattg
    72121 attttatttt aaatatatct atagtctcat ctactaaaga ttctaaacta tcaaattcat
    72181 cataactttt tatcttagac atactatcta gcttctcttt tatcaggtta aatttttctt
    72241 catcaaattt tttaatctta tcattttgtt gtttcacact atctttaatt ttcttaattc
    72301 catctttgat tctatcaggc ttagatttaa taaaatttat actataatca atattttttt
    72361 taattctttt tgatacatca tattcatcca taaagtaatt aaaataatac tcatgaaagt
    72421 tttcaagaaa taagctatca aattcgatat aatcttccat aataaatatt tcagcttgtt
    72481 tatctgcttt ctttattata tttaaaaatc caactatacc catattaaaa aaccaatctc
    72541 ctctataaac tcttaacttc atttatctca cctccattct aaaatatcta catctccaaa
    72601 tccctgagca cgtctaaaac caattcctag attgtagata agatttaaat catcaatatc
    72661 acctttcaat ataaatttac ctttgtaacc attaatatat tgatactctt tacctgttat
    72721 ttttttaaat tctcttaaac tctctttaac tactaccttt ttgagaccta tattttcaaa
    72781 ttctaacttt ctttttaatc cattccccct ataattttta accacttcat tagttatata
    72841 gtttagttct tctatgtatc tatcatcagt tatctccaag aattttcctt ctttagactt
    72901 tacacagatt ggagacaatg cattaaatag taccctttct tctgttacct tcttttctct
    72961 tgataaatcg attctaattc ttgtaagttc ataggcttta tataaacatt ttttagaagt
    73021 cattaaccca ttgtatatat gaaaacccaa ttctaaatct ggagtactta tatttaatat
    73081 tactttatct tctataataa aattgtcacc ttcaatacta tactttttta tataaaccga
    73141 aaatgtaaaa tttttagttt ttttattatt cttttcttta taatagtaca tgtttttata
    73201 gtaatcttca ttagattttc ttattgcttc ttttataata ctcataaaga gcgaattata
    73261 agatattggt atacaacctg tactaaattc aattttcatt ttcataatat cacctctctc
    73321 aattaatata ttaacactag accgtgaagt atattggtcc aagtataaat tatttgaaaa
    73381 aatcagtaaa tttttttcat tttttcaatc tctgacaata tatcatttct aagtctatct
    73441 ggttctacaa cctcaacata agctcccata cttaaaatcc aactttttat ctcctcataa
    73501 cctctcattt tagctttaaa cattatagat ttatcatcat attctatgat ttgttgatta
    73561 ttaacccaaa ctttctcctt tataattgtt gaaaatggat gactaatttt tataacaaca
    73621 ttaatttctt ctcccttata aattcctata ctatttttac tatattcatc ccaactaaaa
    73681 cttttatcta cattatattt ttcttctaaa accttataat ctttaatcct acataattta
    73741 aagtctataa acttaaatct tttttcacaa aaagctacca tataagtatc tgatttataa
    73801 ttaaataaac catatggatg aacaattctt tcactatttc ctgaatttaa tgaataatat
    73861 tctatccaaa atttgtgttt tgtggtatat gctctaatta tttcattaca cttatttttt
    73921 tcagactcat aatcacaatt acgttgtgct tgaactgtaa aataatccat atatgtatcg
    73981 cttttttctc ctgtatttaa tactgctttt attttttcta caatattatt aaattcattt
    74041 ttgtaaatat cattattata ctctaactgt gaatttatca tatctagaat tgaaacttca
    74101 ctatctaata atttaattaa tgatatgcta ttacatttat ctatttcata accaccataa
    74161 atcccaggtg ttgaatttat aaatatacct gcttgctcta aatacatctt gtaacttttt
    74221 atttgccttt cacttacttc caactcttct gataattctt tgcatttcat tttgcctctg
    74281 ctttgaatta atatcatcat tctaagtgta ttagctaatt tactaatgag taaccccccc
    74341 taataacatt aattgatatt tttattattt atttctacac atatgtacat ataacctctt
    74401 tatattttat ataagtagaa tttttttata attttgacat ttaccatatt atattttata
    74461 tttgtacaaa attttaatag ttaatacaat aaaaaatatt actgaaaaaa taaacatcta
    74521 taattccagt aatattaatt aattttaaac cctttttatt atcatttaat aatagtaact
    74581 aaaaattgac taaatttaac cttatctctt ttaaataatt atttcttaca attaaaaaat
    74641 aaactatttg aaccaagaac aagcttccca ttaccaaaac agctgatgat gctacttcta
    74701 tatcaaaaga atttttcagt gcagtaagtg caaatattga atgtataaca gccactacat
    74761 aaggaaacaa aaatactatt ccaatctcaa ttgttgaagc ttttttaatc tcattatatg
    74821 tcatacccaa tttatttaac tgttcatact ttttcttatc aacttggcaa tccatataaa
    74881 atttattata taaaaaacta cttgtagtaa caaagaaaat taaacctata aatattgcta
    74941 aaaatataaa tgtagaatac attaatttcc cagttcctat cattaattct ttagagaaaa
    75001 acaaatatgg ttgcatccct gactcattat taaatttatt ttcaaattct ctgcatatct
    75061 ctatagtttt acttgaatcc tctacttcaa atgcggtaaa tctatccact ataaattttg
    75121 attctatact atcataaaaa ttatccttta ccacatacat atttttgtaa tatgctggca
    75181 taacacattc ttccacttgt tttgccacct ttaaacctct attccctaca ataatatttt
    75241 ctttgacgtt attatttcct ggtaaacttg atgataataa tgatatacat tcattatctt
    75301 caaaacttat aggcttaacc cctatagttt ctgtaatttc taagtactta gattctttca
    75361 taattctgac attaaaatca cttttcttgg gaaatacagt tttaaattca ccattagtcc
    75421 ttgtatagtc tacatcctct ttttttagat tattttctat aaacatcatt ctttccttgt
    75481 ctttttcttt gctatcaggc tttttagggt cattatgcaa tgtcattgtt gaataatata
    75541 ttgtgttagg atatattaaa ttaatttgac gctctacatc tttccaaaag gaataaactg
    75601 tacctatagc agtaaatgct actgcagaag ttatagttat caagaaaaat attctagcat
    75661 tatcctttac cttataaatc aagttcgaaa tccaaagcat atttgtattt tttctataaa
    75721 atctcttgtt taattttagc ttcttcataa aaaatacact aaattgagaa aagaacaagt
    75781 aagttgctac tatagtaagg gatgtaactg gaactaagcg cagatatgtt gtatattggt
    75841 cggttgaggt aatagcatta taatacgcta ttataaacaa acaaatactt aatatagcaa
    75901 gcattagtga tgttttaggc tctggttttg gagtttttgt acctttaagt aacttcaaca
    75961 cctgattttc tttaactata aaagaagtaa atattgatgt taatacagct aaaatcataa
    76021 aatagattaa agtagacaat atcgcattaa atggtatata gaattttaat ggtgataatt
    76081 ctaaaaaagt agacataacc actaaaaata tctttgcaaa gattaagcct attattattc
    76141 caattacaga agatactata tttattatca tattttctat aaagattaat ttcattactt
    76201 ggcgctttga tatacctgta atataaagta ttccaaattc tttatatcta cttttaagaa
    76261 acacactaac tgaataaaac acaaagaaga ataagaatag atatgcaatt atcttactca
    76321 tcttgagacc ttcttttaaa taatcaggaa attgagatac atctaaatct ggatgacttg
    76381 taaacataat aaaagaaaat agcagtgaag atgatataac aatacttgct aagtatccta
    76441 aatacgcttt aatatttctt gaaatattgt taatagcaaa ctgttttata ttcattagtt
    76501 atcgcctccc aataatgtaa gtacatccat tatctcttga taaaactgct ctctactact
    76561 acccttatat atttcattat atatataccc atcttttatg aataagattc tactacagta
    76621 gctcgctgct aatgggtcat gagttaccat catagtagta actttatttt ctttatttat
    76681 cttttgaaat agctccatta caacctttga tgactttgaa tctaaattac ctgttggttc
    76741 atctgctaaa agtattgatg gattgttaat caatgctcta gcaatagcag tcctctgagc
    76801 ttgaccacct gatacttcaa aagttctttt tcctaataaa tcttttatac ctaatattgt
    76861 agatacttca ttcaatctct catcttgctc ttttacactg accttatcta atgtcaatgg
    76921 caatactata ttttctccta tagttaatgt atccaataaa ttaaaatcct gaaatacaaa
    76981 acctaactct cttcttctaa ataatgcaag ttcctcacct cttaacaata aaggattctt
    77041 gccctttaat tccatagttc ctgtagttgg cttgtcaata gtagaaatca tatttaaaag
    77101 agtagttttt ccactaccag atggacccat aattcctaca aattctccat cttctatact
    77161 aaaatttatg tcatttaatg cgttgaaaat tattttttta ccatatactt tacttaaatt
    77221 atttacagtt aaaattttca ttatttaact atccttccta atttaatttt tgaaataaca
    77281 tatatataat tgttaattat aatttatctt agtttaattt ttatagataa taaatctatt
    77341 ttttctatac actaattatg ttagtaaaag ctaatactgc aagtactaca cccatgatta
    77401 ttctgtatac agcaaacact ctcattggtt ttttctttaa aaaattcacg aatttttcca
    77461 taactattat tgatacaata aaagctacta taaacccaac taccaaagca atccacaatg
    77521 ttggtgtcat tattgaataa tcaaattcaa ataaatcttt tcctgaagaa gccaccatag
    77581 ctggtactgc taaaaagaaa gaaaactcag ctgctgtagg agaattaagt cctgctatcc
    77641 atccacccat aatagtagat gcactccttg acatacctgg ccatgcagac aaaacttgta
    77701 atgtcccaac ctttaaaact tgtattggag taattttatc tatattatct gtggaatgat
    77761 tcttttttct aaacaaagtt tctactacta ataataaaat cccacccact ataaatccta
    77821 taattacaga ttgtaaatta aacaatgatt ttatattatc gtaaaataga actcctataa
    77881 tcgcaaatgg tatacaacct ataattacat tcattccaaa tctaaaacca atctttcctt
    77941 cttttccgcc agtaaatata aatttaaaaa attctataac gctatctttt atctttttcc
    78001 aataaagtac tactactgct aatatagccc caagttgtat tacaacctca aacatttcag
    78061 caaattgccc cttaaaatct attaaattac caaccaaaat catatgacct gtagatgaaa
    78121 ctggaataaa ttctgtaagc ccctctacta tagctattat gactgatttc aatataaaaa
    78181 taacatctaa actcatcaat aaacatcctt ccttttttac aaaatttctt tttttatgtt
    78241 atttctctta tgttatttct tatattaatt gtaatttaga ttagaaaatt taactatctg
    78301 caaacattac acaaacctta catctatgta aggtttgcaa ataaactctc ttaaattttg
    78361 attatttaac tatgaatatt tcatttaata aattgtataa taaaaaagta caattaacta
    78421 aaaaccctat tgtaacagat aatttacacc tttattaaac tatttacatc tttattaaag
    78481 tagattgaaa cttctgtacc ttttcctact tctgatttta tacttacttt atgacctaaa
    78541 tcatcacata ccttttttac tagataaaga cccatacctg tagattctcc aaacttacga
    78601 ccattttctc ctgtaaaaaa tgggtcaaat acccttttta aatctttaga aacaattcca
    78661 attccttcat ctattatact taaaattaca tatttattat tttcttcaga ttttatagtt
    78721 aggtagttac tataatcttt agaatatttc actccatttg taattaattg acctattata
    78781 aatttcatcc attttacatc tgtataaaca taagtaaatt tgtctacttg aatcttagga
    78841 atcattccac tttttataaa taaccttttt tcttcattta caatactaga tacaatttca
    78901 tttaatttgg ctttttcaac tataaagtct ttctgaaaat tatctgccct tgcaaaatgc
    78961 atagccatat ctaacccttt atttaatcta tctatttctt ttcttatatt ttcagttact
    79021 tcttctccct cataatcttg aagctgaagg cttataactg atattggtgt tttcatctga
    79081 tgaatccatt ggttgatgaa agttaaatgt tcactatgta tctttttatg ctcttgtatc
    79141 attgattgat acaatttatg ttgttgtttt aaaataactg atatatttct ccccaagaat
    79201 gagcttccta aatacaaaaa tgactcctcc aaagaatgta ctcctttttc aaacagatta
    79261 tatacttctc tatttttata atacttatat attaaaaaac ataacaatat aaaagaacta
    79321 aataaaagaa tatataaact ctctccaaaa ctaataaact tcataagatt acagtaaata
    79381 attgtcataa ctatgcctat ataatatata aaaatataac ctttataatc ttttaaaaat
    79441 aacttcatac tttctcctta ccaattctta tttaatttat atcctaaccc tcggacagtc
    79501 tgaacagcat tatctatacc taattcctca aatcttttcc ttatcctgct aacatttaca
    79561 tttaaagtat tttcctctac aaactcaata tcatcccata tcttttctaa aagataatct
    79621 ctacttacta cttttgggta tctcttgata agacattcaa tcagtatacc ttctttttta
    79681 gttataatta gattctcacc atttaattct agttctaacc tttctggata aaactttaat
    79741 ccatctagct ccactattct ttcgtctatt ttaggtgaat attcaccata tacccttctt
    79801 atatgactct ttatttttgc cattactaca tcatagtaaa aaggttttgt tatataatca
    79861 tctgctccac tttctaaagc tctaatttgg tctacattac catctctagc tgatataaaa
    79921 attataggta aattcgactg ttgcctaata catctacacc agtagaaacc atcaaattta
    79981 ggtaaattta catctaatag aactaagtgt ggcttaaaac tttcaaatgt aatcattata
    80041 tcatcaaagt tttcttcaac aatcacttca aatccatatt tctcaatata atctttaagt
    80101 aatgtactta ttgatatatc atcttccaca atatatactt tataactcat ataattcctc
    80161 ctaatatacc tatttactca ttatataaca gtccaatttt aatatattat aatcttttta
    80221 caatatataa atttaatcat attactaact tcacaattac tgacttcata agtataacca
    80281 tattattaga catcttaata aaactctata aaaaagtatc tttttatgat taattaatca
    80341 ttattatcaa ctaatcattc taaaataaat tgaaattact aattcaaaat agaaaaagtt
    80401 accttaataa ggtaacttaa acttttatta tatttcttac ttagtattat tttatcatag
    80461 tttctactta gcattataga ttaattcttt tatgttcact tttttctctt gtaacttatt
    80521 ttttattaag aagtcttgtg tatcttcaag cgaagatatg tctttatctg ttatatctaa
    80581 actaaaatca taccaagcat ataattcttt agtttcttca agacttaaat caacttcttt
    80641 agctactttt tccatagctt catcaaaatt attatttaca tattctaaag tttccttttc
    80701 aaccttcata aatctttcaa ctatttctgg atgtttctct gcaaagtctg tgctaacagc
    80761 agttactatt ataccatcta ctaaaccttc accatttgct ataagtttac tacctgactt
    80821 catagcttta agagctgctg gaccagcaat caatgcagca tctacgctgc catcagaaag
    80881 agctgctgat gcctctggaa tacccatatt aacaaattcc acatcatcca tacttaatcc
    80941 ttctttatca agtgctgaaa tcaatacctg atgtaatata gtcccttttg ggcctgccac
    81001 cttcttacct actaaatctg ctgctgattt tattgaatta ttattagtca aaatcataaa
    81061 tccttttggt gacctgctat aagtgtttaa tatctttaac tctactccat tagatgcagc
    81121 tattaaagct gatgtaccac ctagtgcatg taagaagtct atttctccag cagctaaagc
    81181 ttgtgtttgc tctggacctg tagtaatttc gtggaagtta acttttatat tatccttttt
    81241 aaattccttt ccaaataaat catcctgttt ctgaattata gaaggaacat ttaatggtga
    81301 ttttacataa gttaaattta tttctgaaag tttttctcca ttattttttt tagcacatcc
    81361 agctaaagat gctgttgcaa gtgttaatat cgttatacct atcaatagct tttttaattt
    81421 catttacttt actccttaaa atattattaa tttctttaaa tgcctttatt tgatttcatt
    81481 gtcattaaaa tatctttttt taatttaata tagtaatctg aagttaaatc tctattataa
    81541 ccatcttcta tattaaattc ttttattttt ctttcgtctg tgaaaacaac tattttcttg
    81601 cctatcttta acgcttcatc aatatcatga gttacaaata tcacgccttt attagttgac
    81661 ttatgtattc ttataacttc attttgcata tcaatccttg taaaataatc taatgccgaa
    81721 aaaggctcgt ccataagcaa catatctgga ttgaaagaaa gagctctagc tatgcttact
    81781 ctctgtgcca tacctcctga caattcattt ggataagagt ttttaaattt ctgcaagttc
    81841 atcatcttaa gatatttttc tacatcaata ttacttttcc tattatattt atttgatttg
    81901 ttcaaattat catttgtttc taagcttcta aaattatcat ttataatttt actgctaatt
    81961 cttttattgt gtttaaattt tctaagcacc ttgtttaaaa tagtattttt tctttgatta
    82021 tgaaaagcta tattttcact tacgtttaac caaggcatta atctgctctc ctgaaaaaca
    82081 aaaccaacat taggtctata ctctttatta tcattaataa acctaatttc accactattt
    82141 ataccttcaa gtgatgcaat tgctctaagc aaggtagtct ttccacaacc actttcacct
    82201 aaaattactg ttatatggtt tctatctatg tttaaagaga tatcactaag aactacatgt
    82261 tcttcattgt caactttata acttttatat aaatttctaa ttatatatcc agagtcacat
    82321 actaaattat tcatatgctt ccaccatctt tcccttactt accttcttca caataatcga
    82381 aaatatgtaa tctgtaatta ttcctaaaag tccaattacg attataccta caataacaac
    82441 atctgttcta gacatttctt ttccatcaga tatcaagtat ccaagaccag atgaagctgc
    82501 tacaagttct gccccaataa ttgctctaaa gctatatcca agagctaact ttaacccaac
    82561 agcaatatca agaatggcat ttggtattat tattttaaat attatctgaa gctttgaaaa
    82621 ctcaaatact ctacccactt caatcagttt tgagtcacaa tttttaatcc ctttcaatgt
    82681 gcttgtaaag attgggaaaa aggatgctaa aactataatt ataatttttg attcctctcc
    82741 tataccaaac cataatataa gcattggtat taaagcaagg ggaggtgtat tccttaaaaa
    82801 atttattaga gatttaaagt attcatatac tccactataa attccaaaga atatccctaa
    82861 aggcacacct atagcagtac ttattgcaaa acctatcaaa actcttttca tacttgcata
    82921 tacattaata aatattgaac catcacttat catatttaaa aatgtactat ataccttttc
    82981 gggtgatggt aatatataat cactccaaat accaagataa tttgtaattt tccataataa
    83041 aagaattata aaaaatatca gaacactctt tactagcctt aaaaacttat tattaaattt
    83101 attgaccatt tacaaaccat ctccattatt acaaccatct ttacaataaa acatttctac
    83161 tatgtcatac ttatcttcaa agccatttct tattttttgt atttcactta atatttcgtc
    83221 ttcacttgat acttcaagaa ctttttcaaa agtatctttg aaatatccta atggaattgg
    83281 tgattcatct atttttccaa gtgattttac accttcttgt tcagcaaact ctttccatgt
    83341 ataaaacata gcattaccct tatccttaaa cttttcactt gcaaagtctc ttaattgtgt
    83401 acatggacag gttactacca acatatcatc tttacttttt atatatttat cgtataaaac
    83461 cctacaagtc cttactaata ttggttctat cataggtact tcaaaatcat ttatcaaatt
    83521 atttcttttt aaaagactta tactttctgg acatctacaa tccaacattg tatttttagt
    83581 cttttttgta tactctttgt actgcttttt tacatattct aactgtggtt cacattctgc
    83641 tattatgtac ccctttttta tcaaatttgc tttaataagg tgaaactttt ctccatacat
    83701 tctttctgcc actggattta ttagaagata tttattcata acgcctccta ttatttaata
    83761 ttgaatatta ttatcaatta atagtttaaa tgagcactta aattttgtca atatattaat
    83821 tttttcttaa taaaacaatt tttatctaca ttttttaata ttttaaatga aatattaa
//
LOCUS       DAEOTL010000008        80700 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEOTL010000008 DAEOTL010000000
VERSION     DAEOTL010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 80700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.008"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            54..923
                     /gene="rsmA"
                     /locus_tag="KRH82_000787"
     CDS             54..923
                     /gene="rsmA"
                     /locus_tag="KRH82_000787"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBG8654081.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            989..2251
                     /locus_tag="KRH82_000788"
     CDS             989..2251
                     /locus_tag="KRH82_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654082.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEGSEE
                     EYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSSDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            2402..3517
                     /locus_tag="KRH82_000789"
     CDS             2402..3517
                     /locus_tag="KRH82_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBG8654083.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIIAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            3703..4599
                     /locus_tag="KRH82_000790"
     CDS             3703..4599
                     /locus_tag="KRH82_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBG8654084.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            4669..5466
                     /locus_tag="KRH82_000791"
     CDS             4669..5466
                     /locus_tag="KRH82_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654085.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(5521..6873)
                     /locus_tag="KRH82_000792"
     CDS             complement(5521..6873)
                     /locus_tag="KRH82_000792"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBG8654086.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            7092..7970
                     /gene="purR"
                     /locus_tag="KRH82_000793"
     CDS             7092..7970
                     /gene="purR"
                     /locus_tag="KRH82_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBG8654087.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            8126..8404
                     /gene="spoVG"
                     /locus_tag="KRH82_000794"
     CDS             8126..8404
                     /gene="spoVG"
                     /locus_tag="KRH82_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBG8654088.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            8617..9996
                     /gene="glmU"
                     /locus_tag="KRH82_000795"
     CDS             8617..9996
                     /gene="glmU"
                     /locus_tag="KRH82_000795"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBG8654089.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            10091..11041
                     /locus_tag="KRH82_000796"
     CDS             10091..11041
                     /locus_tag="KRH82_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBG8654090.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      11885..11970
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            12132..12653
                     /locus_tag="KRH82_000797"
     CDS             12132..12653
                     /locus_tag="KRH82_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBG8654091.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGEYKLIKVG
                     SKLVLQIGTNTEGVTLTEAQSAKLLSDIGEKKIYTSATTNSLGDPLTSNTKIDNKVLY
                     IVLIDNTVMDTTK"
     gene            12805..14481
                     /locus_tag="KRH82_000798"
     CDS             12805..14481
                     /locus_tag="KRH82_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBG8654092.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            14493..15701
                     /locus_tag="KRH82_000799"
     CDS             14493..15701
                     /locus_tag="KRH82_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBG8654093.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            15716..17428
                     /locus_tag="KRH82_000800"
     CDS             15716..17428
                     /locus_tag="KRH82_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBG8654094.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            17421..18329
                     /gene="pilO"
                     /locus_tag="KRH82_000801"
     CDS             17421..18329
                     /gene="pilO"
                     /locus_tag="KRH82_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBG8654095.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            18356..18922
                     /locus_tag="KRH82_000802"
     CDS             18356..18922
                     /locus_tag="KRH82_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBG8654096.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            18959..19486
                     /locus_tag="KRH82_000803"
     CDS             18959..19486
                     /locus_tag="KRH82_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBG8654097.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            19507..21045
                     /locus_tag="KRH82_000804"
     CDS             19507..21045
                     /locus_tag="KRH82_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654098.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            21145..22227
                     /locus_tag="KRH82_000805"
     CDS             21145..22227
                     /locus_tag="KRH82_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBG8654099.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            22208..22990
                     /locus_tag="KRH82_000806"
     CDS             22208..22990
                     /locus_tag="KRH82_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBG8654100.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILSGKQLLELYFSMVI"
     gene            23092..23742
                     /locus_tag="KRH82_000807"
     CDS             23092..23742
                     /locus_tag="KRH82_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBG8654101.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLAFFNI
                     AQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKVFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            23756..24316
                     /locus_tag="KRH82_000808"
     CDS             23756..24316
                     /locus_tag="KRH82_000808"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBG8654102.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            24333..27719
                     /gene="mfd"
                     /locus_tag="KRH82_000809"
     CDS             24333..27719
                     /gene="mfd"
                     /locus_tag="KRH82_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBG8654103.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            27750..28745
                     /locus_tag="KRH82_000810"
     CDS             27750..28745
                     /locus_tag="KRH82_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBG8654104.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            28869..29408
                     /gene="spoVT"
                     /locus_tag="KRH82_000811"
     CDS             28869..29408
                     /gene="spoVT"
                     /locus_tag="KRH82_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBG8654105.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            29528..31141
                     /locus_tag="KRH82_000812"
     CDS             29528..31141
                     /locus_tag="KRH82_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBG8654106.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            31248..32696
                     /gene="mazG"
                     /locus_tag="KRH82_000813"
     CDS             31248..32696
                     /gene="mazG"
                     /locus_tag="KRH82_000813"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBG8654107.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            32785..33063
                     /locus_tag="KRH82_000814"
     CDS             32785..33063
                     /locus_tag="KRH82_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBG8654108.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            33135..33377
                     /locus_tag="KRH82_000815"
     CDS             33135..33377
                     /locus_tag="KRH82_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBG8654109.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            33439..33693
                     /locus_tag="KRH82_000816"
     CDS             33439..33693
                     /locus_tag="KRH82_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBG8654110.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            33694..34227
                     /locus_tag="KRH82_000817"
     CDS             33694..34227
                     /locus_tag="KRH82_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654111.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            34233..34517
                     /locus_tag="KRH82_000818"
     CDS             34233..34517
                     /locus_tag="KRH82_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBG8654112.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            34630..35550
                     /locus_tag="KRH82_000819"
     CDS             34630..35550
                     /locus_tag="KRH82_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBG8654113.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            35640..38012
                     /gene="spoIIE"
                     /locus_tag="KRH82_000820"
     CDS             35640..38012
                     /gene="spoIIE"
                     /locus_tag="KRH82_000820"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBG8654114.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            38363..40255
                     /gene="pepF"
                     /locus_tag="KRH82_000821"
     CDS             38363..40255
                     /gene="pepF"
                     /locus_tag="KRH82_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBG8654115.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            40369..41334
                     /gene="galU"
                     /locus_tag="KRH82_000822"
     CDS             40369..41334
                     /gene="galU"
                     /locus_tag="KRH82_000822"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBG8654116.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNESRELEIQK"
     gene            41834..43438
                     /gene="rho"
                     /locus_tag="KRH82_000823"
     CDS             41834..43438
                     /gene="rho"
                     /locus_tag="KRH82_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBG8654117.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            43591..43791
                     /gene="rpmE"
                     /locus_tag="KRH82_000824"
     CDS             43591..43791
                     /gene="rpmE"
                     /locus_tag="KRH82_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBG8654118.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            43936..44829
                     /locus_tag="KRH82_000825"
     CDS             43936..44829
                     /locus_tag="KRH82_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBG8654119.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            44847..45695
                     /gene="prmC"
                     /locus_tag="KRH82_000826"
     CDS             44847..45695
                     /gene="prmC"
                     /locus_tag="KRH82_000826"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBG8654120.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            45739..46803
                     /gene="prfA"
                     /locus_tag="KRH82_000827"
     CDS             45739..46803
                     /gene="prfA"
                     /locus_tag="KRH82_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBG8654121.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            46932..47612
                     /locus_tag="KRH82_000828"
     CDS             46932..47612
                     /locus_tag="KRH82_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBG8654122.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            47641..48681
                     /locus_tag="KRH82_000829"
     CDS             47641..48681
                     /locus_tag="KRH82_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBG8654123.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            48698..49147
                     /locus_tag="KRH82_000830"
     CDS             48698..49147
                     /locus_tag="KRH82_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBG8654124.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            49164..49616
                     /gene="rpiB"
                     /locus_tag="KRH82_000831"
     CDS             49164..49616
                     /gene="rpiB"
                     /locus_tag="KRH82_000831"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBG8654125.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            49652..50281
                     /gene="upp"
                     /locus_tag="KRH82_000832"
     CDS             49652..50281
                     /gene="upp"
                     /locus_tag="KRH82_000832"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBG8654126.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            50582..51397
                     /locus_tag="KRH82_000833"
     CDS             50582..51397
                     /locus_tag="KRH82_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBG8654127.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPFTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            51623..52060
                     /locus_tag="KRH82_000834"
     CDS             51623..52060
                     /locus_tag="KRH82_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBG8654128.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            52245..52472
                     /locus_tag="KRH82_000835"
     CDS             52245..52472
                     /locus_tag="KRH82_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBG8654129.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            52477..52863
                     /locus_tag="KRH82_000836"
     CDS             52477..52863
                     /locus_tag="KRH82_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBG8654130.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            52866..53570
                     /gene="atpB"
                     /locus_tag="KRH82_000837"
     CDS             52866..53570
                     /gene="atpB"
                     /locus_tag="KRH82_000837"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBG8654131.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            53639..53899
                     /gene="atpE"
                     /locus_tag="KRH82_000838"
     CDS             53639..53899
                     /gene="atpE"
                     /locus_tag="KRH82_000838"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBG8654132.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            54022..54519
                     /gene="atpF"
                     /locus_tag="KRH82_000839"
     CDS             54022..54519
                     /gene="atpF"
                     /locus_tag="KRH82_000839"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBG8654133.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            54516..55061
                     /locus_tag="KRH82_000840"
     CDS             54516..55061
                     /locus_tag="KRH82_000840"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBG8654134.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            55078..56580
                     /locus_tag="KRH82_000841"
     CDS             55078..56580
                     /locus_tag="KRH82_000841"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBG8654135.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            56608..57486
                     /gene="atpG"
                     /locus_tag="KRH82_000842"
     CDS             56608..57486
                     /gene="atpG"
                     /locus_tag="KRH82_000842"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBG8654136.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            57499..58893
                     /gene="atpD"
                     /locus_tag="KRH82_000843"
     CDS             57499..58893
                     /gene="atpD"
                     /locus_tag="KRH82_000843"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBG8654137.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            58896..59156
                     /gene="atpC"
                     /locus_tag="KRH82_000844"
     CDS             58896..59156
                     /gene="atpC"
                     /locus_tag="KRH82_000844"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBG8654138.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            59619..59999
                     /locus_tag="KRH82_000845"
     CDS             59619..59999
                     /locus_tag="KRH82_000845"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBG8654139.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            60014..60475
                     /locus_tag="KRH82_000846"
     CDS             60014..60475
                     /locus_tag="KRH82_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBG8654140.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            60496..61086
                     /locus_tag="KRH82_000847"
     CDS             60496..61086
                     /locus_tag="KRH82_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654141.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            61101..62258
                     /gene="alr"
                     /locus_tag="KRH82_000848"
     CDS             61101..62258
                     /gene="alr"
                     /locus_tag="KRH82_000848"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBG8654142.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            62291..62578
                     /locus_tag="KRH82_000849"
     CDS             62291..62578
                     /locus_tag="KRH82_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBG8654143.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            62547..62930
                     /locus_tag="KRH82_000850"
     CDS             62547..62930
                     /locus_tag="KRH82_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBG8654144.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            63101..63928
                     /locus_tag="KRH82_000851"
     CDS             63101..63928
                     /locus_tag="KRH82_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBG8654145.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            63921..64862
                     /locus_tag="KRH82_000852"
     CDS             63921..64862
                     /locus_tag="KRH82_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBG8654146.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIVKTVKEAIIAKRM"
     gene            65285..66379
                     /locus_tag="KRH82_000853"
     CDS             65285..66379
                     /locus_tag="KRH82_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654147.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            66605..67021
                     /locus_tag="KRH82_000854"
     CDS             66605..67021
                     /locus_tag="KRH82_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654148.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(67203..67772)
                     /locus_tag="KRH82_000855"
     CDS             complement(67203..67772)
                     /locus_tag="KRH82_000855"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBG8654149.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            67926..69083
                     /locus_tag="KRH82_000856"
     CDS             67926..69083
                     /locus_tag="KRH82_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBG8654150.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGASKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKIVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            69248..69603
                     /locus_tag="KRH82_000857"
                     /pseudo
     CDS             69248..69603
                     /locus_tag="KRH82_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(69985..70737)
                     /locus_tag="KRH82_000858"
     CDS             complement(69985..70737)
                     /locus_tag="KRH82_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBG8654151.1"
                     /translation="MEKKSPIIKNIVDSFRIIDVINEKGSIGIAKISEILSIPKTSVF
                     RIVKTLEEIHVIKQLENSDYTLDYRLLSYAKGTSQENKLISVAEPYLQKISKETGESV
                     NLGIRYQNEVIIVKSIEGEFYQLQTTLIPVSPLYCSGMGKLFLSQESEEFLQDYFNNL
                     EKRTVNTITEYNEFLLAKKRILELNLSIDNEEYEYGLSCYAVPIFDCNNDLICAISIT
                     GPSNRLMHKGEEYLIKVLKEQANNLQTEFSKL"
     gene            70987..71904
                     /locus_tag="KRH82_000859"
     CDS             70987..71904
                     /locus_tag="KRH82_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBG8654152.1"
                     /translation="MKVSIIGAGAVGATTAFTLAKTSFVDEIAIVDIDQNRAKGNALD
                     ILHGLSLMHETRIVSGDYDCAINSDVIVITVGVPEKVGESRLVPLQKNVKILQDIIPK
                     ITSTSPNGLLLVVSNPVDIISYFSQKISGWEAKRVIGLGTTLDSARLNYLIARDLKIS
                     QTDIQGLVIGEHGDSQVVAWSQTSVKGTPFLDYVKSNNISLQEDYCNNLAQEVKDTAF
                     DVWDMKGPNCYCVALAIERVIKAIARNEHAILPVSQPADSEMYISQPHIIGRDGVQRR
                     VILSYDTQELNAFDTSYQSLQDIVKQIEI"
     gene            71923..72603
                     /locus_tag="KRH82_000860"
     CDS             71923..72603
                     /locus_tag="KRH82_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HBG8654153.1"
                     /translation="MNISQTKGFFKFLILTLLGIVFLLIPFRFENGMDTILFHYLKLF
                     ISENHAVIQTIVVLLVCLSATLSLIDQLLPNTILRKQRLLKKLFSTTPFYVFNRIMGV
                     IIAMLCYLQIGPKFIISIDTGGAMLDLGTQLSVLVPLMLLFQTLILEFGAMEFLGQLI
                     GFIAKPLFKLSEICAVNIISAWVGPGNAAIIGTKELFEKGYFTVKESAVIGSQFSISS
                     IGWVVLVC"
     gene            72616..73254
                     /locus_tag="KRH82_000861"
     CDS             72616..73254
                     /locus_tag="KRH82_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HBG8654154.1"
                     /translation="MDHFALIFLGITLIGIILAFINVRIPPISNYPDTYVDGSTTSKI
                     VSSTQGTRLQRAIIQSSMRANQVTLKNFTSKIDNMSFYVLWLTPIIIFWGALALIVSL
                     YTPLLTWVSYPIELVLKLANISEPAITASAIMSGFADNYLPVILGKGLESIESKTIIT
                     MMSILQLIFMSEIATLLQSCKVVKSFKDIIIIFLQRTIIALPFVIIFTKLIL"
     gene            complement(73842..74996)
                     /gene="nagA"
                     /locus_tag="KRH82_000862"
     CDS             complement(73842..74996)
                     /gene="nagA"
                     /locus_tag="KRH82_000862"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBG8654155.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNVTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKNPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICMYKVNK"
     gene            complement(75079..75804)
                     /locus_tag="KRH82_000863"
     CDS             complement(75079..75804)
                     /locus_tag="KRH82_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654156.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            76071..77000
                     /gene="pfkB"
                     /locus_tag="KRH82_000864"
     CDS             76071..77000
                     /gene="pfkB"
                     /locus_tag="KRH82_000864"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBG8654157.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLVEIDKYQDLVEVKKLS"
     gene            complement(77129..78046)
                     /locus_tag="KRH82_000865"
     CDS             complement(77129..78046)
                     /locus_tag="KRH82_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBG8654158.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGNIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            78517..79686
                     /locus_tag="KRH82_000866"
     CDS             78517..79686
                     /locus_tag="KRH82_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBG8654159.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            79735..80586
                     /locus_tag="KRH82_000867"
     CDS             79735..80586
                     /locus_tag="KRH82_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBG8654160.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
BASE COUNT        31913 a         8886 c        14600 g        25301 t
ORIGIN      
        1 ataagtataa ttaataaaat taaatatcaa aataagttaa aaaggagtaa ataatggata
       61 gactatcttc acataatgca acaaaggaag tagtacaaaa atataatttt aaattttcaa
      121 agtctttagg tcaaaatttc ttgatagata gtaatataat tgataaaatc ttatctggag
      181 ctagaatcac aagaggagat aatatcatag aagtaggacc tggtatagga actcttactc
      241 gtgagatggg taaaatagca gaaaaagtag tggctataga aatcgataga aatctaattc
      301 ctatattgaa agataccttg tcagatttag ataatacaga ggttgtaaat caagatatac
      361 taaaagtaga catacaggaa ttagtaaaag ataaattaaa tggtgggcca gttaagcttg
      421 tagcaaatct tccatattat ataactactc caatagttat gaaattttta gaggaagaca
      481 tacctgtaac agacatagta gtcatggttc aaaaagaagt tgcagataga atgaatgcta
      541 ttccgggtac taaagattat ggggcattat ctatagctgt tcaatactat tgtgatacag
      601 agattgtggc aaaagctcca agacatatgt ttataccaca accaaatgta gattccacag
      661 ttataggttt acatgtaaga gataaaagaa aatatgatgt tcataatgaa gacatatttt
      721 ttaaaacagt aaaagcatcc tttggacaaa gaagaaaaac tcttcttaat tcgttgggag
      781 gtcttggttt tcttaataaa gatgaaataa gagaagtatt aaaagaagct aatatagacg
      841 aaaaaagaag gggtgaaact cttagtatag aagagttttc agttctttca aatataataa
      901 atacaaaagt atcttctaaa tagaaggtac tttttttaat tttgttaaca tatattgttt
      961 agagaaactg tgttaagggg ggattgcagt gggttctaaa agaaagttta aaagagacta
     1021 tataatacta gaagctaaag acataaactt tagatacaaa gaacgagtac tgccaaaagc
     1081 ttttgcaaaa gttgaagtaa atgatgaaaa agcaattatt gcattatatg tagaaaatct
     1141 aaaatatgtt aaagatgggt ataaagcagt agcaataaaa gatgaccatg gattaataga
     1201 cttaggaaat ataattttaa atgaacaagg aagaggtgaa tttgttttag atttagaaga
     1261 ttatgatgat gagataaaag gtattgcatt attgtatgaa agaaatatac ctttaattgg
     1321 atttaaagga aataagcttg aaaattatga ggacatatta tttcaagagg tagaggaaga
     1381 agaatatgaa gaatatgaag agttggaaga agaagacgaa gagatagagg ataatgagga
     1441 aagtgataga gacgaaggta gtgaagaaga atatattata gaagaatatg atgaagatga
     1501 gtatgaagac tattgggaag atgatgaaga tattgaagaa ggagagttaa aagcaagaac
     1561 ggaagtagaa gattctagtg atgaggaaat agaagagttc aataattata aggaaataga
     1621 aaattataat agggttaaag tacaggaaga atatatagac atagaatatg atgaagaaga
     1681 agaggaagaa gaagtttttg aagtaaatag agaagaagat aggtttgttt cctcaaaacc
     1741 tactaaatca aagaaagttc aaaaagatca gaataatatt gaaaaaataa aaagagctaa
     1801 tggagtaagt caaggagaga gtggaaataa acaaaccagt acattactta tgccaagaca
     1861 aataaaaaaa ggtttgaaat tatttaaaga agtaaaacct tttgtaacag attatataga
     1921 taagacaaga tggtggaaaa tagagataaa tcctacaaca ctgtgtggat atacaatgcc
     1981 ttatttagga tatttaaacg tattgaatta cactatgtat agtgatgcag ttttacattc
     2041 atataaatac agacactatt tatttggagt tcagtatgat gaatataata agagaaaaca
     2101 ttatatttat gctatcccag gaaatagaaa tgaacagcca gacaatggaa gcacaggatt
     2161 tttaagatat caagcttgtg ataatagaac aaatagttta ggatattggc tatgttttat
     2221 agattctaga caaagaaata tagttaggta aaaataataa aaatgaaaaa atttagactc
     2281 aattcttatt ttactgaaaa aattaatgaa atgtagtaca aaactttaaa aactattgat
     2341 aatatttaaa tattacacta caatatatct tgaaatacct attatattat ggaggaaaat
     2401 tatgataaac gagcaaagaa ttttaaatga gtttcttgaa ttagtacaga tagatagttt
     2461 atctttaaaa gaggggaatg ttgctaaagt attagttaaa aaattagaag aaataggttg
     2521 ttcagtagta atagacaatg ctggtgaaaa agcaaatgga gaaactggta atataatagc
     2581 tacattaaaa ggaaataaag aaggaaagaa aatattattt agttcacata tggatacagt
     2641 aactccaggt ataggggtaa aacctatagt ggatgaagca aatggaataa taaaaagtga
     2701 tggtactaca atattaggtt ctgatgataa agcaggtata gcagctatat tagaaggctt
     2761 aagatatata aatgaaaata atatagaaca tactgatata caagttgtat tctctatatg
     2821 tgaggaatgt ggattagttg gagctaaaaa tttagactat ggaaaaatag attctgaata
     2881 tgcatttata ttagatagtg gtggttctcc aggtgaaata atagtaaaag ctcctgcaca
     2941 agatgtaata aatgttaaga tattaggaaa gactgctcat gcaggtcttg aacctgaagc
     3001 tggaataagt gctataatgg tagctgccag agcaatagaa aatatgaatt tacttagaat
     3061 agacgaagaa acaactgcta acataggaat tataaacggt ggaacagcta caaatatagt
     3121 aacaggagaa gttaatataa ttgcagaagc cagaagtcta aaagaaaaca aattagatgt
     3181 tcaaactaaa cacatggtag agacttttga aaaagctgca aaagattttg gagctcaaat
     3241 tgagatagat gtcaatagag catacacacc aatagatgtt agtgaggatt ctgaaataat
     3301 aaaacttgca aagaaggctt tttcaaactt aggtatagaa ggtcatactg aatctacagg
     3361 aggaggtagt gatacaaata tattaagtaa gaatggtatc gaagctataa ctttaggaat
     3421 tggtatgaaa aatgctcata cactaagtga acatatagct ataaaagact tatatgattc
     3481 tgctaaaatg gtagtggaga taataaagga agcataaatt taaataatag tgtataatat
     3541 atatatcgcc tagcttaagc taggtgattt ttcattttat agaagattga taatctctat
     3601 tgaaagcaaa gagtatacat ttgcatataa gagagtgttt aatttatgtt caaatgtagg
     3661 ttcttaataa tatttagatt gtttcataag ggaggaataa atatggaaac aaggtatgaa
     3721 gaagcaaata aaataacaat acaatcaata ctttggaata tagtattaac aataattaag
     3781 gttatagctg gtgttattgg taattctagc gctatgattg cggatggatt acattcagca
     3841 tcagatatta taagttctat aggagtacta ataggcaatt atgtatcttc tagacctgga
     3901 gatagagagc ataattatgg tcatgagaaa gcagagacat tagtatcatt tgtgttatca
     3961 atattgctta ttttcgtttc tataacaata ggtatagagg caattaaatc tttatttaac
     4021 ttagatgcat taagtgttcc atcaatatta ccattagtag tatcagttat ttcaatcctg
     4081 ataaaagagt atcaatatag aataacaata aaagttgcta aaaagataaa ttcaccagcc
     4141 ctaaaagctg atgcttggca tcataggtca gatgctttat cttcagtagc tgcttttata
     4201 ggtataggtg gttctatttt agggtttaaa ccattagacc caattgcgtc agttgtagtg
     4261 gctatatttg tagctaaagt aggaattagt atacttataa gttctgttaa tgaattgatg
     4321 gatgtttcag ttgatgaaga agagataaaa gaattaaaat ttattgtagc agatacagaa
     4381 ggtgttaaaa atcttggtga tataaagact agaaaacatg gagctatggc atatgtagat
     4441 ttgactatat gtgtggatga aaatttgaca gttaagcaag gtcatgatat tgctaccaag
     4501 cttgaaaaac atataataaa acatatggaa tttgtaaaag gcataacagt tcacgttgaa
     4561 ccatgtacta attgccaagg aaataagtgt aataattaat taaaacttaa aaaaaagtat
     4621 aaaaagttat ataattgttt tatgattata aactctaggg gtggttaaat gagcaagaaa
     4681 agaaaactaa agaaaaaagc tgcaatatta ataggagtag ttgttttctt tataatatac
     4741 tttatatcct ttagaatagg aataaacatg gaaaaggata aaagtgaagt gccaaagaag
     4801 gtagaaaaag aagaagaaga taataggtct ttaaggactc aaataaaaga gaagaagaag
     4861 gtttatatat cagataaaaa tatagaaaac ataaaaattg aagaagatat gtgggatgaa
     4921 ataaagttat ttttctcaga ttttaagaaa gtaagaaata ctacttcttc ttacgaagca
     4981 gtttatgaag gttattctga tgatggagtt aaattttcta ctgaccttaa cttttttaga
     5041 gtatatactg taaataaaga agaatattat aaagtaccag ttagttctaa ggatgctttt
     5101 aagaaacttt tagatgagag tatatatact tcgtttgacc ttttaagtca ttataaagat
     5161 tggaaagagg ttactataac tcatggaaaa gaaattaaaa aagttcatag atggaaattt
     5221 gatgatttag cacataagat gatttcaaag agggttgtag gaaaagttca acctgagaaa
     5281 agtaaggaaa gaagtgacta taattttact ataaatataa aaggtgataa ttttgatgta
     5341 aaagttgata caatgggaaa agattatgta aaagttactt ctaagaaaaa tgtatcttac
     5401 tatgaggttc atacaagttt atttgattac cttaaaaatg agatatttga aattggaaag
     5461 aaataagact ttaagaaggc tatcaaatta gatatttgat agcctaaatt attttatata
     5521 ttatttttca accaacaagt ctgcaacctt ataaattgga ccagcaccag cagttattac
     5581 taaatcatta tccttaacat tttcacgtaa gtattttact atatcttcaa attcttttat
     5641 atagatggca tctacattgt tttgatataa tttctcaacc aagtccttag aatgtatatc
     5701 tcctgggtct ttttccctag cagcatatat atctgttatg ataactttat cagcagcata
     5761 gaatgcctct gaaaattcac ctaaaagaga ttttgttcta gtataagtat gtggctggaa
     5821 gatacaccat aaagttgatt tttttaattt tttggcagca gctaaagttg cttttaactc
     5881 agttggatga tgtgcataat catctactac taaagcattc ttatagtacc ctttagtttc
     5941 aaatcttctt ccgacacctt tataaatttt tatatttttt cttatagtct ctaagtcaat
     6001 accagaaaca agagctgcca ttatggcaga agaagcattg tatatgttat gaagaccata
     6061 tacagaaagt tcaaattctc ctaaatctct tccttcatat tctattctaa atattccatg
     6121 accactattg tcaaagtgaa tatcttttat tacagcatca ttgtcagaat ctctgccgta
     6181 ttttataata gtagctttaa catcatacaa tatgtcatca atattttcat catcgccatt
     6241 tattatgaaa tagccttctg ggggtaataa ttttccaaat ttgttaaaag aagccttgat
     6301 ttcatctatt ccagagaaat aatcaagatg gtcttcttca acatttaaaa ctatagatat
     6361 ctttgggtta aaattaagga aactatctac atattcacat gcttcagtta taaagtggtt
     6421 ggaattacct atcttaacat taccacctat catacttaag ttaccaccaa ctagtatagt
     6481 tgggtctaag tctgcatatt caaagattgt agataacata gatgttgtag aagtttttcc
     6541 atgtgttcca gaaactgcta tagaattttt atattccctc atgatttggc ctaaaaaagt
     6601 tgctctgttc attaccaatt tatttttttc tttagcagcc acaagttctt cattgtctgg
     6661 atgaactgct gctgtataaa caaccatatt tacatcatct gatatattat cttttttctg
     6721 accaatataa atagttgccc cttggtccct aagtttgtct aataggtatg attcgtttga
     6781 atccgaacct gaaacttgat aacctttatt gatacatatt tcagctaatg cactcatgct
     6841 gataccgcca attcctataa agtgtatatt cataataaaa ccacctttct ttttaattaa
     6901 gtcctacaat atgaactatt tctgtggtat aataatataa tgttcaatat tttataatta
     6961 atatgcatat aatattatat gtattttatt tttgaatata ataaaacata agtaatatta
     7021 taccacaata agaattgtta tgcattagtt agtttaacgt tatataaagg tacttgtagg
     7081 aggaaataat aatgaaattt aaaagaacag agagaattgg agcaatagtt aaaatactgt
     7141 ctgataatcc aaataaaata tatactttaa gttattttac aaatcaattt aatgcagcaa
     7201 aatcaacaat aagtgaagat ttattagttg taaaaaatgt atttgagaag ctacatttag
     7261 gtaaagttat aactatttca ggagcagcag gaggagtaaa atatatacct aaaacttcta
     7321 tagcagaaaa tgcagagttc ttaatggaat tatgcgagag aatatgtgac aagtctagaa
     7381 tactatctgg tggtttttta tacttgattg acctaattta cgaccctaca atagctgcta
     7441 agataggaaa gatattcgca tcaaatattg agtatgtaga tgcagattat gttgtgacaa
     7501 tggaaacaaa aggtatacct atggcactta tgactgcaaa agctatgaat ttacctctag
     7561 ttataataag aaaagatata aaggtatcag aaggtcctac acttagcatg acatatgtga
     7621 gtggaaacag ttctaaagtt gaaagtatga gtttgccaag aaaagctctt aaaccagata
     7681 gtaaagttat aattatagat gatttcatga ggggtggagg tactataaaa ggaatggtag
     7741 accttatgaa tgaatttggt gcagaggtta taggtactgg agtattcata tctacaacga
     7801 atccttcaga aaaaatggta aaagattata tttcattgat tcaattggat gttaatggag
     7861 ataaaatagt agtagaacca aacttaaaga cttttaaaga tgaatataga aatgaagatt
     7921 tagacgaaga agaagattca gaatttgaat ttgagataga tgaagattaa taaaaaaaat
     7981 atttagaaaa atatgtaaaa ataaaaagag gatatcccta gttgttcata gaattattta
     8041 aaaaacagtt tatattaatt tattccagcg ataataattt taatataaat taatttctgt
     8101 caaaatcaaa gggggatatt ttggtatgaa gataactgac gtaagagtaa gaaaattaac
     8161 agaagaaggt aagatgaaat gtatagtttc aataactttc gataatttgt ttgtagtgca
     8221 tgatataaaa gttatagaag gccataatgg gctatttata gcaatgccta gcagaaaagt
     8281 aggcgaagga aatttcagag atatagctca tccaataaat gcagaaatga gacaagtttt
     8341 agaagatgca gttttacaag cgtatcatga agcattagtt caatgggaag tagctgctga
     8401 ataataataa atatataaaa tggagagagc ccgaacattt aggctctttt taaatgtaga
     8461 atttctatta aaatatgtac tttttagtaa aaaagtgcta tattattagt gataatgtat
     8521 atgttgtata caaattgtta gataaatgta ttataatgta tattgattaa gagaataata
     8581 cgaataaaat taaattagat tgaatggagt gtatcaatga actttaaagc tataatcctt
     8641 gctgctggca aaggaacaag aatgaagtct aaatacccaa aagttataca taaagtatgt
     8701 ggaaaagaaa tggttaacca tattatagat gtttcaaaaa aatcaggggt aaaagatact
     8761 gtcgtgattt taggacatga agctgatgta gttaaagaaa agcttgcaga agaaattata
     8821 atagccatgc aaacagaaca acttgggaca ggacatgctg taaagatggc taaagaatat
     8881 attaatgatg aagatacaat agttgtactt tgtggagata ctccacttat aaaagaagag
     8941 acactaaaga gactatttga atatcatata gaaaataaat atcatgctac agttcttaca
     9001 acaagagttg gaaatccaac aggttatggt agaataataa gagataagaa gggtgacctt
     9061 cttaaaatag tggaacaaaa agatgcaaat tcagaagaaa agatgataag tgagataaac
     9121 tctggaattt attgttttaa tggaaagagt cttagagaag cactagattt gctaaataat
     9181 aacaattcac aaggtgaata ttatttaact gatactgcta aaataatgag agataaagga
     9241 ttaaaagttg gtgcatttgc aggttcaact attgaagaac ttatgggcgt taactcaaga
     9301 gtagaattat caaaggcaga agaaattatg agacgaagaa taaatgaatc tcatatggta
     9361 aatggagtaa ctataataga cactaactct acctatatag aatctgatgt tatgataggc
     9421 aatgatacta taatatatcc aggtgttatg ttacaaggaa aaacaaggat aggttcagat
     9481 tgtataattg gaatgaattc atctataaca aattcagaaa taggtgatgg tacagaaata
     9541 aaaaattcaa ctataattga tagtaaggtt ggagaaaatt ctactgttgg gccatatgca
     9601 tacttaagac caaagagtga cttaggaaat aatgtaaaaa taggcgattt tgtagaagta
     9661 aaaaatgcta ttatagaaga tggctcaaaa gcatctcacc tttcttatat aggagatgca
     9721 catgtcggta aaaatgtaaa tattggatgt ggagtagtat ttgtaaacta tgatggtaaa
     9781 aataaattta aatcaatagt aaaagacaat gcgtttatag gttcaaattc taatttagtt
     9841 gcaccagtag ttgtagaaga aaaaggatat atagcaacag gttcaacaat aacacatgat
     9901 gtcccagatg gtgctttggc aatagcaaga gaaagacaag ttatcaaaga aggatgggta
     9961 gaaaaaaaga atcaaaaaga cgaccaaagt aagtaattat gtagtttatt attttggcta
    10021 aaaaatttag ctcgaaatta ttataaatta tattcattag tattttaaaa ttttcaggag
    10081 ggttacataa atgaatacta gcggaagcga gattaaaatt attgcaggta attcatcgaa
    10141 agagttagca caaaaaatag ctgactatat aggtgtatca gtactagatt gtgaagtagg
    10201 tacatttagt gatggtgaaa tatgtgtaaa catgaatgag acagtaagag gttgtgatgt
    10261 gtttgtagtg caatctacta acagcccagt aaatgataac ttaatggagt tattaatctt
    10321 aattgatgcg ttaaagagag catcagcagg tagaataaca gcagttattc cttactatgg
    10381 atatgcaaga caagacagaa aggctaaggc aagagatcca atcactgcta aattagttgc
    10441 aaatttaata actgctgctg gagcagatag agtattaaca atggatttac atgcagctca
    10501 aatacaagga tattttgata taccattaga ccacttacta ggtggaacaa tattagcaaa
    10561 ttattttaat gaaaagaaaa tagaagattt agtagtagta tctcctgact taggaagtgt
    10621 tactagatca agaaaatttg ctaatacttt aaatggagaa gttccaatag ctataataga
    10681 taaaagaaga ccgaaagcta atgtatgcga agttatgaac ttaataggtg atgttaaagg
    10741 taaaaatgtt atactattag acgatatgat agatacagca ggaacaatag ttaatgctgc
    10801 aaatgcactt aaagagtttg gagcaaaaga tgtttatgct tgttgtactc atggtgtgtt
    10861 atcaggtcca gctattgaaa gaattgctaa ttcagaaata agtgagttaa tagttcttga
    10921 tactatacaa cttcctgaag agaaaagaat agataagata aagataaaaa cagtagctcc
    10981 tttatttgga gatgctataa gaatgatatt ctctaatgaa tcagtaagta aattattcta
    11041 atttattgta tttatgagag ttgtttaaaa ggatataaac cttttgagca actctttttt
    11101 gattttataa ttatggaatg ttattttttt cttgttagaa aggtatatat tattgtaaaa
    11161 agagattata gtttaaaatt atgtatattt aagtaaaata aacttaataa agggcatatt
    11221 attcaaaata ttatgaatat aaaaaatatt acaaaaaagt attgaaaaaa ttcagattat
    11281 gtagtattat gtaaatataa ataaagaaag aaagaggtgt ttccaatggg aaggttagaa
    11341 gatgaacccc taataattaa atgattcagt cacaatctaa agtgaatata aaaatctatt
    11401 gaaagtttat ttataagaat tgaaaatagt atctattcta tctttagtgt ttgtgagagg
    11461 gttctggatt atataagatt actgtaaaga agtaattttg cacaataagc atatctgtaa
    11521 atgaagagtt tcgtttatat aatgattgtg gctgaatcat aactataata gatagaatgt
    11581 ttataataga tgattttata aaatactata ttgtaatagc ttttagcttt caaataaata
    11641 ttagcaaagg atggaaatga caatgataaa actaaatgat aatttataaa tatctcctta
    11701 cgatatataa taattgtagg gagatgtttc ttttttttgt agagtataat ttttctagaa
    11761 attctgtttc aatatgtaaa aagttggtat atataaatag tataaacagt gttgctaaaa
    11821 tatggtagat attatataat ataaatggat atgtatatac attatgagtt atataatttg
    11881 aatttaataa aatagaaacg ttgatttatg ttctgtaatg tgggcacctt ggagcatatt
    11941 gagttagtgg tgcaaccggc tatgaaattg tatttattta taaatactat tattttcata
    12001 gcttttttta tttaaaaaat ggttatatgt tagaaataaa tttggttagt acgtttaaat
    12061 aattttactt agatttttaa ccagatatat tataagtaag tattaattaa aaaatttaag
    12121 ggggaataaa aatgaagtta aaaaagaata aaaaaggttt cactttagtg gaattattgg
    12181 tagtaattgc aattataggt atattagcag tagtggcagt tccagcttta tttagtaata
    12241 taaacaaggc taaggtagca agtgttgagt ctgattatag ttcagttaag agtgctgcat
    12301 tatcttatta ttcagatact aataagatac cagttacacc agatggtcaa actggtttaa
    12361 gtgttttaga aacttatatg gagtctcttc ctgataaagc tgatataggt ggagaatata
    12421 aattgattaa agttggtagt aaattggtat tacagatagg tacaaatact gagggagtta
    12481 ccttaacaga agcacaatca gcaaaattat tgagtgatat aggtgaaaaa aaaatatata
    12541 caagcgctac aacaaatagt ttgggagatc cattaacaag taatacaaaa atagataata
    12601 aagttctata tatagtactt atagataata ctgtgatgga cacaacaaaa tagttaaaac
    12661 aatattttta taaagaatat tgtaaattta atgaaaaata taatataaaa gacaggaaga
    12721 aaatcttcct gtttttttat actattttct ttaatgttca attatgaatg atgatataat
    12781 tgagatagta aaggagtgaa acctgtggct aaaaaagtta gaataggaga caaactggtc
    12841 gaaaaaggat atataacaga agaacagctt aaatgggcac tatcagaaca aaaaaacagt
    12901 ggaaaaagac taggagaatt tctagtacaa gaagggctta tagatagtaa cttactaata
    12961 agtgtattaa aagaactctt ggatatagaa agtatatttt tagaagggac agaaatagac
    13021 actttagcta caaaaatggt tccagaaaat atatgcaaaa gatatactgt atttccattt
    13081 aaaattgatg gaaataaaat atgtctagcc atgtcagacc cacaagatag agaagcagtt
    13141 caagatgtaa ggcgtatgtc tggtaaagac gtagagatat ttatatcaag tacagaagat
    13201 ataaacaaag caataggtca tgcttatgca cattcagaaa taaataaggc aatgactgag
    13261 tacaacaaaa atagaactgg tggagtaaga gaaacagtaa tacttgaaga agatgtaaat
    13321 gctgctccaa tagtacgatt agtaaataac atactagaaa atgctgttag aatggaagca
    13381 agtgatatac atatagaaca aagtgaaaat tacatgcgtg ttaggtttag gatagatgga
    13441 atgttaagag aatatatgag gatgaactca gcaccatata aggcagtaat cagccgtatc
    13501 aagataatgt cagatataaa tatatctgaa aagagaatac cacaggatgg tagaatctat
    13561 ttaaaagtag ataataaacc catagatttt agggtttcta caatgccaac taacagggat
    13621 gaaaagatag ctatgagagt tcttgataag agtaatttta tggttagtaa agaagtacta
    13681 ggaatagacg aacatggctc taagatatat gatgaattga taaacactcc ttatggtctt
    13741 atattggttg ttggccctac tggaagtggg aaaaccacta cattgtattc aatgttaaat
    13801 caactaaata cagaaaatag aaatctatta acaatagaag accctataga gtatgaatta
    13861 cctggtgtaa atcaatctca aataaatgaa aaggcagggc ttactttcgc cagcggactt
    13921 agagctttta tgcgtcaaga cccagatata ataatggttg gagagataag agatactgag
    13981 acagcagaaa tagcaattag agcttctctt acaggacatt tagttttaag tacattacat
    14041 gcaaatacag cagttggagc aatttcacgt cttttagata tggatgtgga aagtttttta
    14101 ataacttcat ctgttttagg tgtaatatct caaagactta cacgaaaaat atgtgagcat
    14161 tgtaaggttt catatgaagc agatattgga gaaaaaaagg ctcttggtat tgatgtaaat
    14221 gaatcagtaa ctatttatag aggaaaaggt tgtgaaaggt gtaataatac tggatataaa
    14281 ggacgtctag gtatatttga aatgcttgaa attactccag aaataaaaga gttaatagat
    14341 tcatctgcaa atcaaagaga aattttaaag atggctagaa aacaaggtat ggttagctta
    14401 aaagaggata tagttaaaaa agttttaaat ggaaagacaa cagtagaaga aatgattaga
    14461 ataattttga tgactgatta aaggatgata ttatgaaaag ttttaaatac acagtaataa
    14521 aagaggacgg aaaaaagcaa actgatgtga ttgaagccaa cgattttaat gaagctagaa
    14581 atcttcttag aaagagaaat cttagagtta ttgaaatcaa agaaagcaaa aataaaaata
    14641 taagattatc tagtagaaag agaaaaaaag acttgggagc tgaccagata agccactttt
    14701 gcagacagtt tgctattata gtatcttctg gtataaatag tatttctgga ttagaaacat
    14761 tagctagaag gtcaaccaac attacattaa gagaagaaat taatcgtata gtggcagaaa
    14821 taaaagtagg ttctactatt gcagattcaa tgctttcatc aaaatcaaag tttccaaagt
    14881 tactcggtgc tatggtagct acaggtgaag ctacaggtaa attagatgaa gtattaaaaa
    14941 gtatggcttc attttatgca agtgaacaca gggttaaaca aaagcttaga aatgctgcaa
    15001 catatccatt aatagttttg atttcttcat ttataatgat ttttatattt acaacattta
    15061 tggtacctaa gatgattaat tcaattacaa cagtaggagc aactcttcca cttataacaa
    15121 gaattgttat ggggtttggt atgtttatga agaagttttg gataatagta ctcttagtta
    15181 ttatattatt tatctatcag tttaaaaaat atctaaaaac gtcagttgga agggctcata
    15241 aagatagagt tataaataag atacctgttt taggaaaagg aataaattgt atggtagcta
    15301 cacgattttc aagagcattg tatctatttg tatcaacagg atacccatta gttcaagggc
    15361 ttgattatat tatagatagt gtaaataaca ccatggcaga gaagatttta gcatcagcta
    15421 aagatggaat aacaagagga gaaggcttag cagaaaattt agagagatat acgtattttg
    15481 actctgtgtt ggtacagatg atagctatag gggagcagac aggggaatta gagaatataa
    15541 gtagacagat ggcagaattt tatgagtatg aatccgagat ttatttaaat aggatggcct
    15601 caatgataga gcctgtttta ataattgcag ttggtattat agttgcgata ctggttgtat
    15661 caatatttat gccaatgctt agtatatatg atgccatgta ggagggaaag gacaaatgaa
    15721 caaggtttat gtatcatatt atggcgattc tatttccata gttgagggca gatataaaca
    15781 cgataaggat aagttttatg taaaaaattt taatgtgttt tcaatagagg atattgcaca
    15841 agatttttct aaggaaaagt atgctctatt gagatacgca ttagaaaatg ttaagttaaa
    15901 atcaagacat gtagtttttt gtttaaatac aagagatgta attttaaaac cccaaaaact
    15961 tcctaatatg gacaaaaagg atttagatgg atttatgaag ctagagatgg acgaaatgat
    16021 ggctttggag tcagatgaat atgtattttc gtatgaagta tctagtgaaa cacctgataa
    16081 ttcagatggc gatgaatcaa gcttaaatct tatcattgga gctatacaaa aggaagaggt
    16141 aaatgcaatt gtagagataa tgcatgaatt tgatttagta ttagatagaa tagatacatt
    16201 atcaacagct tacttaagaa tgcttaaaaa tttagactac aatgatataa tggtaaccaa
    16261 tataagtgac aatagcacaa ttataaatat atataagaaa gatactttat ttattagtga
    16321 taatatacct ataaagataa ctgctaaaga tatggacatg caattattaa atgtagtaga
    16381 agaatcaaaa ggtcttatga attactattc gtcaagaaac tttggtaagg ttacggatac
    16441 tatattaata ttaggaaaaa gatattccaa taaattaatt tatgaaactt ttagctctgc
    16501 attttcaagc tatgtttctc aaggccttac tgagataatg gatatatctg atatgataac
    16561 tggagatata gatgaagatg atataaattc aattgtagag cttttaggaa gtatgataga
    16621 acctaaaggg aaaagagatt ttgaaaatat aaacttttta ccaatggata tacttagaaa
    16681 acagataaaa gctaaacaaa tgaaaaacat actgaaaatt gctccaatag ttattttgat
    16741 tcttgctata ccttatttat gcttaatttt ttcaaataat ttagcaaata aggaacttga
    16801 aaatgttaat ggtgaaataa gaaatattga atctgcatat tatcagattg gaaatataga
    16861 aaaaatgata cagagtaaaa gcgaagaaat aaaggtatat gatatgttaa ttgggaaaaa
    16921 ggtaaagtgg gaaaatttat tggatgatat agataaaaat actccaagta aagttgaact
    16981 aacaagttta tcaacaactt atcaaaatct tggaactaat aataaagctg ataattcaaa
    17041 aagtaataag actacaacag ataaatcaag taacaatgaa acaaaatcaa gtacgaaaag
    17101 tgatagtaat ggagataaaa cagataatga tttaaatgaa gataagacta caaatgtgtc
    17161 agaagcatta actggaaata gtgagactaa tagtaataac acggataaag atgataaaac
    17221 tccattgtat gataagatac caaatgttat aaatatagaa ggaaatgcta aagattcctc
    17281 ttatgtaggt caatttttat ataaattaaa gggattatac tatttcaagg atgttaaatt
    17341 acatagcata aaaagtaatg cagaagattc taactataca tttagtatga cattatacct
    17401 gaaagaaggt gtattaacta atgaataaag atatatttaa aaaagatata aaagatatat
    17461 ttaaaatgga agttagtcta aaagggattc ttataaaggt tataatttta ttagctattt
    17521 tatcatatgg ttattttgga ctttaccctc aatatcagaa atatattgct acaaaaaatt
    17581 ctgtaaaaca ggctactgaa aaattaaata tatataaaga gaaaactgca cttatgccaa
    17641 aatatgaaaa acaacttgaa gaagttgaaa gtgaattaaa agaaaaaagc aaaaatcttt
    17701 tatatgatat gcaagatggt ctttttttaa taggtttaga taaaaaaatg aaggcttata
    17761 atattgactt aaccagttat gacgttggaa atgttaaaga atacgaacat ttttatggta
    17821 tatcaacaac aataagtgtt agaggtgatt atagaaatgt caaaaaatta atggcttatt
    17881 tagaagaaca aaaaaatgtt actcaaatac tagattatac aatgacttca tatatagaac
    17941 cagaaaaaga agaggaagaa acaacaaaca ataaggattt aattaaaaat gtgaacataa
    18001 ataaagatac aaaaatatac tgggtggaag gcgaaaataa gtggcattta tataaggatt
    18061 gtccattgat aaaagaggga gagattataa aaaatgacaa acttttagat aggtctacta
    18121 attatctatg taatacttgt gtacttagag ctgcaacaga aaaagaagca aaaaaagaag
    18181 tcgtagctcc aaaggcagaa ggtgtagtag atgctacatt taaatttata atgtacacta
    18241 aagagaatac tacaatgata cttgatacag ataatccatc ttcatggagg ccaggaaaat
    18301 ataatccatt taagtctagt gcgaaataaa gctaagtaag ctttaaagat aggtgatgag
    18361 tttgtacaaa aataatgaaa aaggtcttac tttattagaa gtaataatag ctgtttttat
    18421 actgacaata gttttaagta tttcttataa agtgttcaat ggtataacat cagcagtaaa
    18481 aaagcaacag attattacag atgctcaagt aaatattaat ctaattaata agtatctaaa
    18541 tagagatttg gaaaactgta aagaactaac taaaactggt tcaggtaata attatgaata
    18601 caatatagag atgccagata atgttgtaaa atatgaagtt tctatagaaa ctaaaaaaaa
    18661 tacagaggta tattctgtaa cgagaatcca aaacaataca attgatacag aaaatgaagt
    18721 tagagaagaa ataatctata atcaaccact agttcaaaac aataaagaaa tgaaggaaac
    18781 accatttaaa atagaaaagc aaactggtaa atctatttat actgtaagta tatactataa
    18841 tgaatcagtg caagaaagtc ataaaaatag caatttaaat aacaaaactt atacatttga
    18901 tgttatgtca agaatagggt aataagaatt tattaaaaaa taagtaggtt gataaaatat
    18961 gagtaaaaag aatagtgaaa gaggattttc cttaattgaa gtgttagtag ctatggctat
    19021 tatgggaatt gtactatttg cattttttaa tattatcaat actaataaca aagcaaacac
    19081 taaaaatgac acagatataa cttccttaaa ctatgttcaa agtgaaatag aaaatctaag
    19141 agaaaagata aaaagtggag aatttgattt tgatagttta gataaactag aagatggaac
    19201 tgtcgtatat gaaaaattaa tagataaatc aaaaaaagtt gtatatgata aagttcttag
    19261 tgaaggtgat gtgagcttat atgatactcc atatgaaaag attacaacaa taaaagatga
    19321 agatggtaat ttaatcgaca aaggaaatat tacaaataag ataaagacta ttgtagaaga
    19381 taaaagtggt cagatatata aaatagctgt aactgggaaa agcatgaatg actattcaag
    19441 taaaaaagag gttaaaattg taactgaaat atttaaagat aaataatttt acttgggggt
    19501 gagattttga ggaagtggaa taaatttaaa agtgaaagag gggcagcttt agttttagtt
    19561 ttggttgtag tagcattgct ttctattgtt ggattgatat tttcaaatca gatagctaat
    19621 agaataaaat ctacaaagac tactaatgaa ggtatacaag caaagtattt agcagagaca
    19681 tgtgtggaaa atagtattga taaagcatat gaaaaattgt atgatgagct tgagaaaatg
    19741 gataatgagt ttaaaagtga aaatcaagaa aaatccatat ctaggtcaaa attaagaaat
    19801 atatcagatg aagattttaa taatcaagat gaggaaaata ttgaagcaga aagacttgga
    19861 tatatgaata atataaattt ctatttaaat aaagcttctt cagacttgga aaaagctagt
    19921 atggaattga aaaagctata tgatttagat atgttggact atagagacat tgaatatgta
    19981 gatgcaaata ttatttcaca tagagattct atcttagaaa tttgcaagaa ttatacttct
    20041 ggagatatta gtaaaataaa tgaatatatt ctgaaagaag atatagactc aactacattg
    20101 attgaggcaa agttagtgaa taatgatatt cttttaaaaa tgtttttaga agaaaataaa
    20161 attgaaaatg aacatttaaa ttcagccttt tcacatactt ataaggcatt agataacatt
    20221 tctttggcga tgcaaaatat gattgagtat agacatacgt ttcatataga tgagccaaaa
    20281 gtagaagtat ctaatgggat tccagactct caacaatatt atgaactaat acaaaatcct
    20341 ataataaata gtatggagta tagctggaat agtaaatggg atacattaga aaacctattg
    20401 gaaattttac caaatcaaac tcaaggattt aattctttaa gagttcattt gagaaataat
    20461 gtaagaaaat ttgagaagtt aagcgataat atatctagtg gtaaaaaaaa tacagcaaaa
    20521 aatttcttaa agtataaaga gttattgtat gaaatatcag accaatgtaa tcaactaaaa
    20581 agtatgtctt atgagaaaat acctgttaaa tatgataaca tggctttgat aacaactttt
    20641 gactatatac aaaatgagct tttagcagag ataaaatgca gattaaaaga attaaaacca
    20701 caagaaattg ataaaacaga aggtattact ataaaaatac ctttttataa ggctgactac
    20761 gacatgacaa aagaaggatg gcctaaatta aaagaaaatg gttcaggggc ggagttaagc
    20821 ttaatggtaa ctggtgataa aaatggaata aaagaagtag aagttacaga tggtaaaaaa
    20881 aatattattg gtttaggtgt tgaagaaaat tcaaattcaa agtataaggt tgacgccatt
    20941 gtaaacttta atctaaatat agatacaaat gtagttggaa attatgatat aaaagataaa
    21001 attttgatta atcatgatat aagttcatac aaaaaagtaa actaaatata agaagcaact
    21061 tagtataaat aaataataaa ataattttat tatttactac taaaaaaata agtaaactaa
    21121 tagaagatat ggagagtaaa tattatgtat atttatgatt tattagagca aggtataaga
    21181 ctaaacgcat cagatataca cataacagtt ggaacaaatc ctgtagctag agtaaaaggt
    21241 ggatttgtaa aactaagtga acaaatattg acatcagaag taacaatgca aatggcaaaa
    21301 gacatagcag gggaatctat gtttaaagta atagaagaac atggagaagc tgatttttca
    21361 gcttctctaa aaacaggaga aagatttagg gtaaatgcat ataggcaaaa aggaaattac
    21421 gcaatagcaa taaggactat aacagcagaa attccaacat ttgaaaaatt aggccttcca
    21481 gagagtataa aatcttttac tgaaaagcat aaaggattag ttttagttac aggtccaaca
    21541 ggaagtggta aaagtacaac acttgcaagt atgataaata taataaatga aaaacaacaa
    21601 aaacatataa ttacacttga agacccgata gaatatgtac atcaccataa acaaagttta
    21661 gtaaatcaaa gagaagtagg aactgataca gaaagttttc attcagccct tagagctatt
    21721 ttgcgtcagg acccagatgt aatactaata ggagagatga gagaccctga aactgtttca
    21781 atagcattaa cagcagcaga aacaggtcat ttagtatttt caacactaca tacagtgggg
    21841 gcagctaaga caattgatag aatagtagac atgtttcaac catcccaaca gcaacaaata
    21901 aaaacacagt tatctacagt ttgtgaaggt gtggtatcac agcagttact tcctacagca
    21961 gatgggaaag gcagaatagc agcaattgaa ttgatgtttg ctactccagc aataaaaaac
    22021 ctgataaggg aaggcaaaac atatcaaatt ccaaacatga tacaaactgg agttaaagta
    22081 ggtatgaaaa ctatggacca agatttaatg gaactttata aaaatggaaa gattacaaaa
    22141 gatatggcac ttagtaggtg tactgaccaa gagtttatga caagaatgat aggtggagta
    22201 aactacaatg gatattataa tcgttaatct atatgtattt atagtgggta tagtgtttgg
    22261 aagtttcttt aacgtctgta tttttaggat tccagaaggt atatctattt ctagaccacc
    22321 ttctcattgt atgagttgta atactagact aaagccaata gacttaatac cagtgctaag
    22381 ctatttaatg agtggcagaa agtgtagata ttgttatgag aaaatttcta gtagatatgc
    22441 tatagtggaa ttaattacag gacttttatt tttaacagta tttatgttat atggaatatc
    22501 tacatcaact atttattatt tggttcttgt gtctttactg attataatta catttataga
    22561 tattgaccac tttataatac cagataaaat attggttttt ggagctatat tttctatgat
    22621 ttttaacctt ttatttaaag aaattccagt taaggattca attctaggtg tttttatttg
    22681 tggaggaagt gtctggatta tagttctttt gattgaattt gtaataaaaa aagagtgtat
    22741 gggtggagga gatatcaaac tatttgcaat gctaggactt tacatgggtg ttaaaaatgg
    22801 tcttttgaca gccttactaa gcgtttatgt aggagcagtc tatggaatct gtgtaataat
    22861 tataagtaga ataaaaggaa aggaatataa ttctgttata ccatatggac cttttatatc
    22921 tattggagca ttaataacaa tcttatctgg aaagcaatta cttgaacttt atttttctat
    22981 ggttatatag atgatagtca agttaaataa agttttaatt taaaaaaatg aattaaagta
    23041 tttaataagg acaatattat tattaaccct attactaaag tgctacaaac tatggagtat
    23101 ataataataa tttccttatt ttttgcacat ttgataaata aatctctatg tgttttttgt
    23161 gatagagaaa agaaaaattt atataatacg ttttttattt acataataac tgtagtttta
    23221 tctgtattaa tatatctaaa atttgggatt agtgtagaat gtgtacaata tatggtttta
    23281 attccatttt taataattat atccattgta gattactaca caatatatgt atatgatata
    23341 acaatagtta gtggtataat agttcaaggt ataatttttt tggccttttt caatatagct
    23401 caatttgatt atataaatca tatatttgga ctattgatag gctttattat accttatatt
    23461 attgctaaac taacaaaagg attaggctat ggagatgtag gtctctatag cttatgttgc
    23521 tttgcattgg gaaataatta tgggttttat gtgatagttt tatcatttat tttagcgttt
    23581 ttgtttttta ttattttata cataactaaa gtatttaaag atgtagatat aagaaagcaa
    23641 attcctttta caccttttat ttccttgtca acaattttaa taatatttac agagtataat
    23701 atatttaatt tttattataa tttgttatac aaatttatat aacaggaggt aagaaatgta
    23761 cgtagtagta gggttaggta atccaggaaa gaagtatgag aagactagac ataacgttgg
    23821 atttgatgtt atagatattc ttgctaaaga atacaatatt agtgttacta aaataaagca
    23881 taaagctttg attggtgaag ggagagtagg tactgaaaaa gtattattag ttaaaccaca
    23941 aacttatatg aatttaagtg gagaaacatt aatagatata tataaatatt ataaggttga
    24001 tttaagtaat atagtagtag tatatgatga tatagattta gaagttggaa agatacgtat
    24061 aagaaaaaaa ggaagtggag gaactcataa tggcatgaaa tctataacta agtgcctagg
    24121 ttcaaatgac tttccaagag tgagagtagg tgtatctaaa ccagaagctg gtcaagactt
    24181 agcagacttt gtactttcta gatttagaaa agaagaatct gataacataa atgaagcatt
    24241 agaaaaagcg gcagatgcta ttgactcaat aataagagaa aatatagata tgtctatgaa
    24301 caaatataat ggatagtgag agggagattt aaatgaatga tgttttttta tatcctttgc
    24361 aaaattcaaa agagtataaa gatataataa actgtataaa aaatacaaaa ggctcattat
    24421 tggttaatgg acttttacca gtacaaaaac ctcatatatc gtattctata tttaatgatt
    24481 tatcacgaca aatgattttt ataacgagta gtgatttaga agcaaagaaa gtatacgaag
    24541 atttaagttt ttatatggaa gataaagttg aatatttagg ttttcaagat atttattttt
    24601 atcacttgga tgcaaaggac agaaacgaag aagcaaagaa attaaaagta ttgttaaaac
    24661 tagcaaataa agaaaaaatc attttagtaa cttctattga agcagtttta agaaaataca
    24721 taccaaaaca agttttgctc gatagtgtat ctcattataa ggtgggagat agcttagact
    24781 tagaaaagtt aactgagaaa ttagtttcat tgggatatga aagagtttca aaaatagagg
    24841 ggtttggtca atttagtata agaggtggaa ttattgatgt attttcactt gaatatacaa
    24901 atccaattcg tatggaatta tttgatgatg agatagattc catacgaact tttgatgtat
    24961 attcacaaaa atcaattgat aaattgcaac aattctctat aactccatct agggaattta
    25021 tttatcccga aaaaactaca gatgcattag ttaaattaaa aaaagaaaca actaaaaata
    25081 ctgatgaagg tacatttcaa aatatagatt atatatcaag taagacttat tttgaaggtg
    25141 tagagaacta tatagattat atttatccag aagaaaacaa aagtatattt acttatttag
    25201 cagatgatgc aatagtattt atcaatgata taacgagact taaagaaaga tgcgaaaatt
    25261 atataaatga gtttagagaa aattataaat taaatcttga aagaggtctg gctattaaaa
    25321 accaaggtaa attgttatat cactatacag atttagagta cttagtaaaa gacaagtctg
    25381 tggtattaaa ctcattattg ccaaagtcta taaataactt ttctataaaa tctataataa
    25441 attttgaaag tagagaagtt cctacattta atggaaaggt agatttgctt gtagaagaat
    25501 taaatcggct gaaatataat ggatacaaaa taattttagc aacaaataca ttagaaagag
    25561 caaataaatt aggaaaagat ttattggaca aaggcttaga aacgaccatt tctaaagata
    25621 gagatattga aattaaatct tcacaagtta taattgtacc tgcacacata aacagtggtt
    25681 ttcagtataa atctataaag tttgttgtta taacagataa cgaaatgata ggtgtttata
    25741 aaagagcgtc taagactagc aataaaaaag ttaaaaaggg aaagaaaata gaatcctttt
    25801 tagatttaag tgttggagac tatgtagtcc atgaaaatag tggtgtaggt agatacacag
    25861 ggattgaaca aattacagtc aatgctatta aaaaagatta tatgaaaata gtatatcaag
    25921 gtggagataa tctatatgtg ccaatagacc agatggacaa agtacaaaaa tatattggtg
    25981 cagaagtaga aaaagttaag ttaaataagc ttggaacaaa tgagtggacg aaagcaaaag
    26041 caaaagttaa aaaagaaatt gaagatatga caaaagactt gattgagctt tatgcaaaac
    26101 gtgaaaaaat acaagggtat aagttttcaa aagatacacc ttggcaggca gagtttgaat
    26161 cgttgtttcc atatcaagaa acagaagacc aattaaaggc tatagaagaa actaaaaaag
    26221 atatggaatc aagtaaggta atggataggc tagtatgtgg agatgttggt tatggaaaaa
    26281 cagaggtagc tattagaagt atttttaaag cttgtatgga ccaaaaacaa gttgctgtat
    26341 tggttccaac aacaatattg gcccaacaac attataatac attcaaagag aggtttgaaa
    26401 attatccttt gagagtagaa gttttaagta ggtttaaaac accaaaacaa caaaaacaga
    26461 ttattgaaga tgctaaaaaa ggattagtag atattttaat tggaacacat agaataatat
    26521 ccaaagatat aaatttacca aacttaggtc ttgtagtcat tgatgaagaa caaagatttg
    26581 gagtaaaaca taaagaagct ttaaagaaaa ttaaatctac agtagatgta cttacacttt
    26641 cagcaactcc tataccaaga acattacata tgtctttaag tggaataaga gacatgagtg
    26701 ttatagaaga acctccacaa gaaagacatc ctgtaataac atatgttaca gagagtaagg
    26761 aaagcgtaat tcaagatgag atagagagag aattaagtag aggtggacag gtattttttg
    26821 tatacaatag agttgaacac attgaagaaa tggcaagtat gattcaaaaa ctcgtaccag
    26881 atgctagagt ggctgttgca catggaagaa tgacttctaa atcattagaa aatataatcc
    26941 taggattttt aaataaagat tatgatgtac tagtctgtac tacaataatt gaaactggta
    27001 tggacatatc aaatgcaaat acaatgatta tatatgatgc agataaaatg ggattggctc
    27061 aactttacca attgagaggt agggttggaa gaagttcaag acaaggatat gcatatcttt
    27121 tgtatgaaaa agataaaact ttaagtgaga tagcggagaa gagattaaaa gctatcagag
    27181 aatttacaga gtttggttct ggttttaaaa tagcaatgag agaccttgaa ataagaggag
    27241 caggaaatat tttaggttct caacaacatg gtcatatggc agttataggt tatgatttgt
    27301 acgttaaaat gcttaatgat gcaattaaaa aagtcaaagg tgaacctatt gtggaggaaa
    27361 ttgatgttga aatagattta agtgtaaatg catacattcc agataattat atcaaagatg
    27421 agttgattaa aattgaaatg tataagaaaa tagcttctat tgaaaacaaa gaagacatgt
    27481 tggatataca agaagaactt gaggatagat tctctgatat acctaaacca gtccagacac
    27541 ttcttacaat agcttatata aaatcgttat gtaagatatt aaaaatagaa aagataagac
    27601 aattaaaaga tgaaatatta ttagttccaa taacaaagta tagaactaaa cagaaaatag
    27661 gttataatat agttacagaa ttagaagaat tattagaaaa gatgtgcaag gtaaaataac
    27721 ttgtaaattt aagaagggat gttttaaatt tgaaaaaagt aataacattg gtaatagcta
    27781 tgattttggt agtatctgtg actgcttgca gttctagtaa aggagaaact gtggcaacag
    27841 ttgaaggtac aaagatatca tcagatgaat ttaaaaaaac tatagctctt tataaagatt
    27901 ctatggaaca aacttatgga aaagatatat gggataagga agttgaaaag ggtgtaaaat
    27961 acaaggacaa gtttaaagat ttaattcttg accaacttat aactacagaa gtaatatatt
    28021 ctcaagctaa aaaagataac ttacttccta aaaaagagga tgttgaaaaa agttttaaag
    28081 aattaaaaga cgctatgggt aaagatgaaa aatataaaga acaacttaag aaattaggta
    28141 tagatgatga gtttttaaga gaccaacaag agaaagattt agcaatgcaa aactatcaaa
    28201 gtaactttgc taaaaagact aaaatatcag atgaagaaat gaaaaaatac tatgatacac
    28261 ataaagatga atttaaaaaa gatgaggtag aagcttctca tattttattg aaaacagtag
    28321 atgataataa caagccactt tcagataagg aaaaagctga agctaagaaa aaggctgaag
    28381 aggctcttaa agaagttaaa tcaggtgagg attttgcaaa agtagcaaaa aaatattcac
    28441 aagatacttc agcaagtgat ggtggtaaat taggattctt ttcaaggggt caaatggttg
    28501 ctgaatttga agatgctgct ttttctatga aaaagggtga agtatctgat ttagttgaaa
    28561 ctcaatatgg ataccacata attaaagtga cagacagaat aaatgagcaa acatcatttg
    28621 aagatgctaa agaaactata aaagaccaac tgttgaaaaa taaatatcaa gaacaaatag
    28681 aaaaattaac taaagaagct aaggtagaaa aagatgaaaa agtaataaat aaaatcacaa
    28741 tctaagactt aaaaaaagag taatatgctt aaaaaagcta tatctggata agatatagct
    28801 ttttttgtat atttttctta acaatggtaa aaataaactt aaagtaattt atggagggat
    28861 taaaaaatat gaaagcaaca ggtatagtta gaagaataga tgatcttgga agggtagtta
    28921 tcccaaaaga gataagaaag acattaagaa ttagagaagg agacccttta gagatattca
    28981 cagcaaaaga tggagaagtc atacttaaaa aatactctcc aataggtgaa ttaaatgaat
    29041 tttcgcaaga atatgctgaa acattagctg aagtactagg atatggagtg ttgataacag
    29101 acttagattc tataatagct gtgtctaagc ttcctaaaaa agattataaa gaaaaaagta
    29161 taagtgatga gttagaagca ataataagtg aaagaacagt aaaatattca aaagataaaa
    29221 acattttacc attattcaag gaagaccaaa aagaatatac tagtcaagtt atcatgccta
    29281 taattagtgc atctggtgac tgtataggtt caattgtagt tgtttcaaag gataaagata
    29341 caattgcaga aagtgaagaa aaatctttaa aaattgctgc taacttttta ggaaaacaag
    29401 ttcaataatt ttatcataaa gaccttttac atgaaggtct tttgaagttt ttgtgtaaaa
    29461 tattgaatat agcattaaaa atatggtata ttaaagtttg ttatataaac agtatggagg
    29521 ttatgttatg aacaataaca aaaataaaga ctcctttcta aaaggagccc ttatacttgg
    29581 gctagcaggt gtaatcgtaa aaataatggg tggatttttt aggattcccc ttggaaacat
    29641 gattggttca gaaggaatgg gatactatca ggctgcttat cctgtgtata ctctattttt
    29701 aacattagct actgctggat ttccaacagc tgtggcaaaa ttggtttcgg aaaaagttgc
    29761 aattggaaat tttaaaggtg caaataagat atttaaggta tcacatacag ttttattcat
    29821 taccggtata atatcatttt gtatattatt ttttggagcc gactacatag taacaaacgt
    29881 aatgaaaaat ccaggtgcgt tatactctat gaaagccatt gctccagcat tactatttgt
    29941 tcctgcaatg tctgcatata gaggatattt tcaagggaga caagatatga ctaagattgc
    30001 tgtgtctcaa gttgcagagc aattttttag agttgtatta ggtcttactt tggcctactt
    30061 gcttatgaag agtctaggtc agacttttgg tgcagcaggt gctatatcag gggctacaat
    30121 aggttcaata gcatctatgc tttatttggt gtttgcttat atgctaggga gaaaagagcg
    30181 tagagcagag atagatgcaa gccaaagatt taaagatgaa agagtgtctt atatttttaa
    30241 aaagctttta actgttgcca ttcctataac aataggagca tcagtaatgc cacttgtaaa
    30301 tatgatagat aatgttattg taataagaag acttatggaa gcaggcttta catacaaagt
    30361 ggcaaattca atgtttggtc aattaacagg tatggcaatg gccacaataa atttaccagc
    30421 agtcataaca actgcaatga gtatgagctt agttccagca atttctaaag catatgcatt
    30481 aggaaataag tcaaaagcta gaaaagatac taagagtgca gttaaggtaa ctttacttat
    30541 agtattgcct tgtgcgtttg gtatggcttc tttagcaata ccaataatgg gtcttttatt
    30601 tccacatgaa ccatcttctg taggaactat tttgtttact cttactccat gtgtattatt
    30661 tttaggatta atacagacat tgactggtat aattcaggga atgggaaaac caatagtacc
    30721 tgtaattgct ttatgtgttg gtatgctatg taaaattgta ataagttata ctttaacagg
    30781 tataccagat attaatgtac tgggttcagc atttggtaca gttacagcat actttgtggc
    30841 agccatgatt aacttactat atgttaaaaa acacatgaat gtaaactttt ctaaaaaaga
    30901 atttataata aagccattta taacagttat gacaatgttt ataatggtta agttgagtta
    30961 tggtgcttta gttggattct taggaaacag catatctaca ataattgcaa tatgtgttgg
    31021 tggaattgta tatgtagtag taatacttgg aataggtgga attaaaaaag aagagattct
    31081 aactatgcca aaaggtgata aattatataa attgttaaaa aaagttaaac ttataagata
    31141 atataggaat atatatgcaa ataaaggaaa tactatacaa atagtaaatc tccttatttg
    31201 tataataata taaaaataaa gtgaaatttg ctaataggag tgatgttatg ggtaagataa
    31261 gtattgtagg tcttggacca ggagactatt ctcttataag ccaaggtgtg ttagaatctt
    31321 taataaatag ccctaaagtt ttttttagaa cagagaaaca tccaataatt gataaactta
    31381 aagaaactat acaatacact tctttagact acttttatga aaaagaggaa aattttgata
    31441 atgtttattt gaaaatatct gaatttatca tagaagaatc agcaaagggt gacctagtgt
    31501 atgctgttcc tggtcatcca agagttgcag agaagactgt aagtataata gagagattag
    31561 ccaatgaaaa gcacatagca gtagaaatat tgccttctat gagctttgta gacgctatgt
    31621 ttaactattt ggctatagac ccatctgagg gatttaaact ggtagatgct tttgaaatag
    31681 aaaattcata tatagacttg gatacaagca tgataataac tcaggtatat gataaattta
    31741 tagcatctaa tgtaaagtta aaacttatgg aacattatga ctataatcaa gaagtatgta
    31801 tagtaaatgg agcaggtgtc aaagatttag aaagtaaaaa gtttataaag ctttgtgaat
    31861 tagacagaaa tgaaaacttt tttgactatt taactagctt atatataccc aaaagttcta
    31921 aaaagatgta taatacagta catgacttag aaataatagt taatacactt agaagtccat
    31981 ctggatgtga atgggataaa aaacaaacac atcaatcatt aaaaaattct gttatagagg
    32041 aagcatatga actttgtaat gcaattgata ataatgatat agatgaaatg gtagaagagt
    32101 taggtgatgt tcttttacag gttatattcc attgtcagat aggaaatgag gagggctact
    32161 ttgatttaaa agaagtagta aatggcatat gtaaaaaatt aattcataga catcctcata
    32221 tatttagtgg tgcaaaatta gatatgtcta agtttgagaa aacttgggaa gaattaaaga
    32281 aagaagagaa aggcgaaagt actataacag atggccttag aaggatacca aaacatttac
    32341 cagctcttat gaaggctagt aaagttcaac ataaagcagc acttgtcggc tttgattggg
    32401 acaatgtaga agatgtattt aaaaaaattg aagaagaata tcaggaatta cttgacgaac
    32461 acagggtcgg gaatataaaa tacataaagg aagagctagg cgatttatta ttttcgatag
    32521 taaatctagc tagattttta gacatagact caggagaagc cttgaactgt actacagaaa
    32581 aattcataaa tagatttgac tttatagaaa aaagtgcaat gaacttgaat aaaaaattag
    32641 aagacatgac acttgaagag atggatgagt tttggaatca ggctaaaaaa caataaaatt
    32701 gtggaaggaa atttgtcaaa aatctagaac ttttatcaca aagatagaag tctatattat
    32761 aaacattttt aggaggtaaa tatcgtgaat aaagctgaat tagtatcaaa gatggcagaa
    32821 aaaagtggat taacaaagaa ggaagcagaa gctgcgttaa acgcatttat gagttctgtt
    32881 caagatgcac tagtaaataa tgaaaaagtt caattagttg gatttggaac atttgagaca
    32941 agagaaagag ctgctagaca aggaagaaat ccaagagatc cagagcaagt tatagatata
    33001 ccagcttcta aagcaccagt tttcaaagct ggaaaaggat taaaggatat aataaatgga
    33061 taattagaaa tcttgtgaaa aagtgtggat aaatttgcca cactttttct atagaaccaa
    33121 ggaaggtgat aattatgaga ttagataaat ttttaaaagt atctaggatt ataaaaagaa
    33181 gaactgttgc taaagatgca tgtgataaag ggattgtcac tataaatgga aaagttgcta
    33241 aatcttcttc agaggtgaat attggagata cattagaaat acaatttgga gagaagaaga
    33301 tgaagtttaa gataaatgaa gtaaaagagc atgtattaaa aaatgatgca aaagaaatgt
    33361 acgaaatttt agaataaaat taatagtcct ctagtatatt aatagtagta ttattgaaat
    33421 atttactggg gggatattat ggaacagaac ataactttga aagatagatc aaagctggtt
    33481 atttcgggag tcgagcacat atactctttt aatgacaaaa gagtagagct caaaacttct
    33541 gtaggcgaga tggtaattga aggcgaaaac ctagatatga gcaagctaag tatagacgaa
    33601 aatataatta gcatagatgg aactataaat tctatggtat atgcaaagcc taaaaagcca
    33661 caagagagtt tcttgaaaaa ggtatttaga tagatgatac cttttactca agatgtaagc
    33721 attttttatg ctactattta tggtggaata ctcatagggg tgttgtttga tttttataga
    33781 gggctaagag ggaattttaa attcatcaat tattttgcta taatctttga tgtattgttt
    33841 tggtttctag ctacggttat aatattcgta acaataaacc ttacagaatt ttttgattta
    33901 agatattatc attttgtggc tttgtttatt ggttttattt tatactataa caccataagt
    33961 aaaattgttt tatcaattat caataaaata attcgttttg tgagaaattc ttttaaaaaa
    34021 gttacacatt acatagtcag ttttttaaat aatttgtatt acgttataat ctattcacta
    34081 cacctactat ttgatattat attttatata ccaaacatat ttatagcaac aagaaaaagt
    34141 ataaaaagaa aatcaaataa aaaattaaag aacaagaaaa aatcaaaacc taagaagaaa
    34201 aaaaataaaa ctaaaaaaag ggtgtaggaa aaatgaactt aagaaaaaaa ttttcaggac
    34261 agattattgt tatcagttta tttttaggaa tatcaatttt tagtatgatg acaggatttg
    34321 tatttgagta tacaaaagct aaggaatata aaaaagaaat agcaagtcta aataaacaat
    34381 taaaaaagac tgaaatacaa ataaacagct taaagaaaga tgaaaaatca tatgaaggag
    34441 acttagagga tatagcaaga aaaagattga atatggtaaa accaaatgaa acagtttatg
    34501 tagacataaa tcgttgatta aaacttgcta ataagtttac agatgtattg attttaaaat
    34561 ttaagattta ataaaaaagt cattcagtta aggatggctt tttgttttta ttgaggaggg
    34621 aatttcataa tgaaagtagg agctatagat attgggacaa actcaatgag attattgata
    34681 gcagattata gagatgggaa ttttataaac agaaaaaaat ttgttaatac aactagaatt
    34741 ggttatggtg tggatagtaa aggatatata aaagaagatg ctatcaaaag aaatataaaa
    34801 gcattaaaag aattttctga taagtgtaat gatgaaaagt gtgaaaaaat ttattgtatg
    34861 gggacatctg ctcttagaga cagtaaaaat ggagattact ttgttaaatt agctaaagaa
    34921 gaaactggaa tagatgttga tatagttacg ggaatagaag aatcaaattt gggctttaag
    34981 ggtgttttag aaggaataca aggtgatgat actattattg ttatagatat tggaggaggt
    35041 tcaacagaat ttattgtagg tgattcagaa ggaattatat ttaataaaag tgagaatgta
    35101 ggtgctctta ggatgacaga gaggtttttg aagcacgata ttattgaaga tgaagagttt
    35161 gaagctatga gttcatttat atatggtgag attgataaaa cgttaaatca tataaaagac
    35221 agaggattaa aaactcttat aggtatagga ggtacgatta catcattatc agcaatgaat
    35281 caagaattag agatttactc tatggaaaaa atacataata gtaaaataca caaaaaagaa
    35341 atagaagaaa ttctacaaaa attaataaag atgacattaa gtgataaaaa gaacttaaaa
    35401 gggctacaag aaaaacgtgc ggatattata actgctggtg taaaaatatt gaatataata
    35461 atggaaaaat tagaaataga agaaataacc gtaagtgaat acgataattt ggaaggctta
    35521 atatgtcaaa agtcaaaaaa aatgtattaa tattttttga tttttaaaac cgattatgac
    35581 aaaaaaaatt actcctcttt gttacaattc ttaatataaa caaaagagga ggttttttta
    35641 tgcaaagaag tgtagcagtt gtgaagaata agactgtaaa accaaatgtc ataaaattaa
    35701 taagcggata tattgatttt actacggcgg cattcgctgt gatgggattt ttacttagta
    35761 ggtctattat agtagactct gtagctcctt taggaattgc cttttttata tgtgcatcaa
    35821 agattgataa gtacaagata cctgtattca tatcaacatt attaggaata ttgttatcat
    35881 ctaatgattt tggaaatgta gcaaaatatg ctgtgtgcct tacaatattt atggctatga
    35941 ataaaaaatt aaaattatca gattcaattg ctaaggttgc atttataggt gcaataatac
    36001 tacttccaat ctccatggga caagctttct tttcaaatag gtatgtatat ggtcttctta
    36061 tagcaggagt agaagcaata ataatgttta tatctatata tgtgttttct tatgggatag
    36121 gtttaatggc caatgtcaac aataggatgt ctgtacggac agaagaagcc atatcaataa
    36181 gtttactgct aacctttagc ataatgggaa taggagatat atctctgttt ggaatatcaa
    36241 taaggaccat tttatcgacc gtattgatat tgctgacctc aatagtaggt ggagctacca
    36301 tgggagcatc tagtggtgta attattggtg tagcatccat tttaaataat atgacatcag
    36361 ctgtttatat ggggatatat tctttttcag gattaataag tggagcattt aataaaataa
    36421 ataaatattt ctgtatacta ggatatattc taagttggac aataatatac ctatatactt
    36481 ctggtattac ttctaatatg atgcaattaa gagatatact attaggttgt ttgatagtac
    36541 tagtattgcc agagcgatta tttaataaga ttgaaaaatt aataaaaagt aatgtggctt
    36601 caaatgaaat cgtatacgat tatattatga gaagcaaaaa cctaactaat agcagattga
    36661 acagtattta taaaacttat gatgaccttg cagatacatt tgataagata agagaaaaag
    36721 acaaagtgct agaccaaaga gacatagcta atgtaataga tatgattcat aatgatgaat
    36781 gtaaaagttg tagtatgaga agaatgtgct gggagtcaag atttaatcat acatacacta
    36841 tgatatataa cattcttgaa aaaattgagg agaaagggga gttaagtcta aacgatatac
    36901 ctaaaaattt tagaaaggaa tgtatgaaac cagagtcaat agtgaaaata tcaaatcact
    36961 attacaaaat gtttgtatta gattatgatt ggagtgtgaa gttttcagaa agtagaaagt
    37021 taatagcaaa tcagataaga agtatttcaa aatccattaa atccttatct caagatttag
    37081 aaggcgacat aatgctagat atagaaaagg aaaaaaatat atatgaacag ttagaaagat
    37141 atgatataac agttgataaa gtaagttact taacaaaaag taacagtgag tttgaaatat
    37201 caatagaaaa gaaaacttgc catgatggat gtatgtgtga agataaaatt gtaaatataa
    37261 tttcagacct agtaggtgaa aatatgtctg ttagaaaaat aggatgtcac tgtttaggag
    37321 gtaaatgcaa ggcaacattc gttaaatctc aaaaatataa ggctgttaca gaagtttcag
    37381 caatgtcaag ggatgggcat atcctttgtg gagacaatta cacatacatg gagataaatg
    37441 atggtaaata catgatggct ataagtgatg gtatgggaaa gggtaaaaaa gcatatgaag
    37501 aatcttctgc cactattgat atactggaaa aaatgataga tgcaaaaatt aaagatgaga
    37561 tagtcattga tactataaac aatatgttgt tgttaaaatc ttcagaagag atgttttcaa
    37621 ctctggattt gggaatttta gatttaaaac gaggttgttt agaaactata aagatgggag
    37681 cgtgttctac ttatataaaa agagaggatg gagaagttga cttaatatca tcatcatcat
    37741 tacctgtggg tatattatca gatgtaaaaa ttgatagaaa aaatgtaaaa gttaaggaag
    37801 gagactatgt tataatggtt tctgatggaa ttgtagatgc aggaagaaat aacaatttag
    37861 gagacaattg gttaatatac ttcttaaaga atatagagac tacaaatcca aaggaaattt
    37921 caaatttaat attggataga gcattagagt tacaagcgtt acaaatcgaa gatgacatga
    37981 ctgttttagt tacgaaaata tgtacaaaat aaggtttaca agattatgtg tataagatgt
    38041 ggataacttg tgtataatat gttaatagac ttttgaaaaa agtatagtta ttaacaaaaa
    38101 taacatataa atcaacaaaa tttgttgata agtatggcag aaatgttaat aaaatgtaaa
    38161 aaaagaaaaa acaaaagcta ttatcaaaag agattcatgt tgaaataact aaatttctaa
    38221 gtaaagaaaa cctgtgaata tgttgattat tatgtggata actattaatt cgatatttat
    38281 ttatatagta tgaataattg aataatatat ctaaaaaaag ccatcctatt attaagtaaa
    38341 cttattgaaa ggatggcttt ttatgaatag aaaattgtgc aaagcaataa tacctttatt
    38401 tatttctatt ttttgcatgt taataataag tataaaagct gaccaaggat atcaaaagaa
    38461 taatgacaga gcaattactg tcatgaataa taatgatact gaagatgatg ctgaaaaaaa
    38521 acaagaaata gactatgaaa aaacatgttg gaatttgcaa tctttgttta aaagtgatga
    38581 ccaatggaaa aaagaactta agagttttga taaagatact aaagagttga aaaattacat
    38641 aggtaaagta acaaaatcgc caacacattt gtcttttgcc ttgaacatta aagaaaaact
    38701 tgatataaga ctaaataaac tttctgccta tgtaaaatta aaacaagata ctaataaaaa
    38761 ttcgtataag tacttagata tgaatgatag tatgagtaaa tcctatggga attatatggg
    38821 gatttgttca gatttagagt tagaaatact aaaattatca aacaaagatt acaagaaaat
    38881 tatttcaaat aaaaatataa ataggaaata tggtgcatat ttaagagata taagaaggaa
    38941 taaagtacat tatttggatg ataaatcaga agatattcta agcaaagtat cttcaataag
    39001 tagtcttcca agccaagtat atgaattatt tagaaatatg gatagaaaaa ctaatttgac
    39061 accagctcaa tatgcgagtg aattagagtc atcagataga gaaaatagaa aaaaagctta
    39121 tcaagatgaa cttataactt acaatgataa tataaataca attgcaggtt taattactgg
    39181 tcaagttaaa aagaatattt tttattctca ggaaagaggt tatgagtctt ctttagaaat
    39241 gtacctggaa tctgataatg tagatgaaaa agtatacaat aatttgataa ggactgtaaa
    39301 tagtaatatg gacagtctac acaaatatat agatttaaga aaaaaagtat taaaattaga
    39361 taaggttcat tcatatgata tgtttgtgcc tatggttaag gctgttgaca ataatattaa
    39421 ttatgaaaag gcacaaagta tagtatattc agcgttgtca cctttaggaa aagaatacaa
    39481 tgatgtagta tataaagctt tcaatgaaaa atggatagat gtttattcac atgaaaataa
    39541 agtaagtggt ggatactgct tatctgttta tgaaaatcat ccatatatac ttttaaatta
    39601 taataattca ttaggttcag tttcgacctt atcacatgag cttggacatg ctgtatatga
    39661 atatttaagt tctaagaatc agaattattt taattcaaat ccgtctatat ttactcacga
    39721 agttgcatct acaacgaatg aagcattact ttacgagatg cttataaaag aagctaaagg
    39781 caatgatgaa aaagcttatt atataacaca gtatttagac ttgataaaag atactcttta
    39841 tacacaaact atgtatgctg aatttgaaaa aactatacac gagttagtag aaaaaggaaa
    39901 aagtgtaaac gcattagtat taaatgatgt ttggggacaa cttcttaaaa aatattatgg
    39961 acaaagctat gaattagacc aattatctaa ggtcggatgg gctagaatcc cacattttta
    40021 taatagtttc tatgtctata aatatgctac aggttgtagt gcaggagtaa gttttgccca
    40081 agacatccta aagaatggtt cagataacta tatgagcttt cttaaaaagg gaagttcaga
    40141 ttatccaata aacttgttaa aatcaagtgg cataaattta actaatacaa aacccataga
    40201 aaatacaatc aaaaaatttg atagtttagt agcagaactt gaaaagctat tataaacatt
    40261 attgtaatcc acatggtaaa tatatcgaat taatgataaa atatactaaa agtttaaagt
    40321 cctatcaaga taggactttt tatttattaa ttagtgggag atgattctat gcaagttaaa
    40381 gttaaaaagg ctgtaatacc agcagcaggt ttaggaacta gatttttgcc agctacaaag
    40441 gcacaaccaa aagagatgtt accaatagtt gataagccaa ctctacaata cataatagaa
    40501 gaagctgtgg cctcaggaat agaggaaata ctaataataa caggtagaaa taaaaaatct
    40561 attgaagacc actttgataa atctgtagaa ttggaacttg atttagagaa aaaaggtaag
    40621 aaagaattgt tggaggtagt acaaaacata tctaacatga ttaacataca ttatataaga
    40681 caaaaagagc caaaagggtt gggagatgca atttattgtg cgaggcattt tataggtgat
    40741 gagccgtttg cagtaatgtt aggggatgat attgtagata atgatgtacc ttgtctaaaa
    40801 caactaacag atgcatatga ggaatataga actacaatat tgggtgttca aaaggtaaat
    40861 caagaagata ctaataaata tgggataata gaagcaaaaa atatagaagg tagagtttac
    40921 aaggtaaaag acatggtaga aaagccagag tcaggaaaag ctccttcaaa tattgctatt
    40981 ttaggtagat atataataac tcctgaaatc tttgatattc ttaaggattt accaccaggt
    41041 aaaggtggag aggtacaact tacagatgct ttaaaaatat tatctaagaa agaagctatg
    41101 tatgcataca attttgaagg caagagatat gatgttgggg acaagctagg atttttagaa
    41161 gctactgttg actttgctct aaagaaagaa gaccttaagg aagattttat aaaatatttg
    41221 aaacatgtat gtagtgaatt tgataaaaat aacaatgtgt tatacaataa tacagatgaa
    41281 aaaatagatt taattgaagt caatgaatct agagaacttg aaattcaaaa ataattaatg
    41341 aaaggtgatg tatggtggca aaatcaagtc agaaaagaat taatagaata atagctgttg
    41401 ggattgtggg aatcctcgta ataacgagta taacagctgt tttgagtatg attgcaacta
    41461 tgtaataaga taaatgacag cagttgatat acataaatat aaaaaccata tataacttga
    41521 tgtagtcaaa aacttacaat attttagtta tatatggttt ttagaattta taaatgtaaa
    41581 aaaaaatttt tataatagtt gcatatttta aaggaaaata ttattataag atataaatat
    41641 agtgataaat ttataaaaac gtgctaagat tggacttgaa atacagtaat atagtaggta
    41701 ataatgtttt aaattttatt tattgaccat aatatataaa taatgatatt attagactta
    41761 actgtttaaa taaaactttt ctttttcatg ccttcaattt ccaaaataag tatgtatata
    41821 aatgaatata tagatgagga ggattttttt gattttagat gataaagtat tagaaggatt
    41881 aggtagtaag accttagttg agctacgaga gatagctaaa gaattaaaaa taaaatcaat
    41941 tactacatat aagaaaaatg agttaattga gattataaat tccaaaagta aaaatgagga
    42001 aaaagtaaac gaagagacta aagaaaaaaa tgaagatatt aaagaagaca taaagaatag
    42061 aaaagaaaat atagagcgtg aaagtataga aaaagaagtt gaatataaga gccctaccaa
    42121 atcatacaac aagaaagaaa tagataccca aaatatttcc caaaaccaag aacatagaaa
    42181 tcaaagaaat gactataata agacaacgag tgtaaatgat agcaataagt catcaaatat
    42241 atctaataga atggtcagaa ataataataa aaactattat atgcctaaac aagttgatga
    42301 atctaagata gtagatgaat ttaacacatc aaaagaggat gaagtagtag gtgtacttga
    42361 aattctgcca gatggatttg gttttttaag aggttcaaat tatttgtcta ctgaaggaga
    42421 tgtttacgtt tcaccatctc aaataagaag atttaatatg aaaacaggag acaagattaa
    42481 gggaataact agacatccaa aaagtggaga gaaatttaga gcacttttat atgttcaaaa
    42541 aataaatgat gaaaaccctg acacagctat acaaagaaat gcgtttgaga cattaacacc
    42601 aatatttcca gaagaacgac ttacactgga aactaataga aatgaaatag ctacaagaat
    42661 tatagattta atttcaccta taggaaaagg acaaagagga ttgatagtag cacctccaaa
    42721 agctgggaaa acagttcttt taaaaagcgt tgcaaatagc atagctaaaa atcatccaaa
    42781 tgttgaactt atagtactcc ttatagatga aagaccagag gaagttactg atatgaaaga
    42841 atctattgaa ggagacgtta tatattccac ttttgaccaa gtatcaagtc atcatgtcaa
    42901 ggttgcagag atggtgttaa atagagctca aagattagtt gaacatggta aagatgtagt
    42961 aattttacta gatagtataa ctagattggc aagggcatat aaccttacaa tatctcctac
    43021 aggtagaact ttatctggag gtattgaccc tggtgcactt catggaccta aaaagttctt
    43081 tggtgcagca aggaatatta gacagggtgg ttctttgaca atattaggaa cagcattggt
    43141 tgaaactggt tctaggatgg atgatgtaat atttgaggaa tttaaaggta caggaaatat
    43201 ggagttacat ttagatagaa aattagcaga aaaaagaata ttccctgcaa tagatattta
    43261 caagtctggt acaagaagag atgatttatt gcttgatgat gaagaaaaga ctgctctttg
    43321 gagattaaga agagaaatga gtaataattc agtaatggaa attacagata aagtcattga
    43381 acttataaag agaactaagg acaataaaga gtttgtaaaa tcaataaaga atttgtaaaa
    43441 tcaataatac aaatgcaaat atggattata taaactaata gaaaaatcac ttgaatggca
    43501 taataagttg tgctataata atgtagttga taatgtaaaa agaaagttaa tataattaat
    43561 ttttttaaat aaagagaaga ggtgactata atgcaaaagg aaatacaacc aaaatacaat
    43621 ccagttgaag tgcgttgtgc ttgtgggaac acatttgttg ctggttcaac taaggacgaa
    43681 ataaaagttg aaatatgttc agagtgccat ccattctata caggaaaaca aaagaacata
    43741 gaaaaaggtg gaagaatcga caaattcaag aaaagattca aaatggacta atttttataa
    43801 aagtggagtt ggaggaagcc aactcctatt ttattacaaa aaaacattca tattctactt
    43861 taaattgtct ttttgtatta taataataaa tatgtaaaat tgagtattct aaatacaata
    43921 aaatgaggtg agtggatggc aaaacaagct gtaggtgggc aagctgttat tgaaggtgta
    43981 atgatgcagt caaaagacaa aagagcggta gctgttagaa aaagtgacgg agaaatagca
    44041 ctaaaagaag atagaataaa aagttgggta agagataaga atatagataa gatacctttt
    44101 gttagaggtt cttttgttat gatagataca atgattcaag gcataaaaag tttaaacttt
    44161 tcttcagagt tttttatgga agaagctgaa gaggataaat ttgatttatt tataaagaaa
    44221 atttttaaag ataaggcaaa tgatataatt ataatatttt cattggtcat agcaatgtta
    44281 ctttctgctg gattattcat ttttatacct acattggtag gaggagcttt ttctaaagta
    44341 atgcctaatg attttatgct taatttaata gaaggaatca taaggatagc tatattattt
    44401 gcatatatag tattgatttc acgaagtaag gatatagaaa gagtctttca atatcatgga
    44461 gcagaacata aatctatata ttgctatgaa aatgatttag aacttacagt agagaatgct
    44521 agaaaattta aaagattaca tcctagatgt ggtacaaatt tcctatttat agttatggct
    44581 gtatcaataa tattgtttgc attttttggt tggccaaatc caattcttag aatatttatg
    44641 agaattatat gtgtgcctat agtagcaggt ttatcttatg aggtaattag agttcttggg
    44701 aaatatgata atggatttac taaaattatt gcatatccag gaatgatgtt gcaatatttt
    44761 acaacaaaag agcctgatga tgagcaatta gaggttgctt tggaagcatt gaaagcagta
    44821 gtagattaga gaaaaggata tttgttatga cgataaaaga tataattatt aaatattcag
    44881 ataaactaaa agatataagt gatactccaa gattagatac agagttattg ttacaaaaaa
    44941 cattgggtgt tgatagatta tatattcact taaatctgaa taaagagcta actgaagaac
    45001 aaaaaacaaa atttatgggt tttgcagaag aaagattaaa tggaagacca atagcatata
    45061 tagttgaaaa tagggagttt atgggattag atttttttgt taaggaaggc gtattgattc
    45121 caagaccaga tacagaaact ttagtagaag aaataattga aatatgtaga gaaaaaaaag
    45181 atgtaagtat attagatata ggaactggtt ctggagctat tacaataagt ttagcaaagt
    45241 acattgaaaa ttctaaaatc atgtcttttg atatatcaga gacagcatta gaaatagcta
    45301 aaaaaaatgc tattataaat gaagttggtg aaaaaataaa gtatattaat tctgatttat
    45361 ttacagcaat aagtgatagt aacataaaat tcgatatcat agtttcaaat ccaccatata
    45421 ttaaaaaaca agatatagaa actctgcaca aacaagttaa agattatgaa ccatataatg
    45481 ctcttgaagg tggagaagat ggattagact tttatagaag aataacagaa caaggtaaga
    45541 aatatttaaa taagtgtgga atattagcat atgaagttgg tcataatcaa gctgaagatg
    45601 taataaatat tatgaaaagt aatggatata aaaaaatata tacaaagaag gatattcaag
    45661 gcattgatag agttgttata ggttacaata tatgatataa tcaacaattg atatgttaca
    45721 tttaatcgag gtgaaagtat gttaaaaaaa ttagaggtat tggaagatac atataaagac
    45781 ttaagtgaaa aaataggtga tccggatgta ataaatgatc aaaaagtttg gcagaaatat
    45841 ataaaagaac atgctgactt ggaacctatt gttatgaaat acagagagta taaaagcgtt
    45901 ttagatagta taaaagaatc aaaagaaatt ttacaagaag agtcagatga agaattaaga
    45961 gaattagcta aaatggagtt agctgagatg gaagaaaaag tagcacctct ggaggaagaa
    46021 ataaaaatac tattattgcc taaagaccct aatgatgata agaacgttat agttgaaatt
    46081 agaggtggag ctggaggaga tgaagcagct ctatttgcgg gtgatttatt tagaatgtac
    46141 tcaaggtatg ctgaaagaag aagatggaaa atagaattat tgagtgcaag tgatactgga
    46201 gttggtggat ataaagaagt atcttttatg ataaaaggta aaggtgctta ttcaagatta
    46261 aagtatgaat ctggagttca tagagttcaa agaataccat caactgaatc tggtggaaga
    46321 atacacacat caacttctac tgttgcagta ttaccagaag ttgaagatgt agaggttgaa
    46381 ataaatccaa atgatttaag aatagatgtt ttccgttctt caggtaatgg aggacaaagt
    46441 gtcaatacta ctgactctgc tgttagggta acacatatac ctacaggtga agtagtatct
    46501 tgtcaagatg gaaaatcaca attaaaaaat aaagagcaag ctttaaaaat attaaaagct
    46561 agactttacg ataaagcatt ggcagaacaa cacaaagata tagcagcaga aagaaaaagc
    46621 caagtcggaa caggagacag gtcagaaaga ataagaacat ataatttccc tcaaggtaga
    46681 ataagtgacc atagaataaa tttaacttta tataagttag atgcattctt agatggagat
    46741 atagatgaaa tgatagatgc tttaattact gttgaccaaa cagaaaaaat gactgcaata
    46801 taagtaatgt tttaaagaag ctgtttcttc ctagaaatta ttttctattt tgaaacagct
    46861 attttgcatt ttaggtcatg ttatcatatt ctattgtata taattgttat atacaagtat
    46921 aggagggtta tatgatacta aaagtaacaa taattgggct tttggcaggt gttataggga
    46981 caggattagg aggagtaata tcagccattt ttaaaagaga ggtcgataaa tatctaagtt
    47041 tttttatggg attatctggt ggaataatgt tggctgtagt ggtgtttgat ttaatgaaag
    47101 aatccatgga caaaatgggg ataatcaata cagttatatt tacgtttgtt ggagctctca
    47161 taactatgta cataaaaaca aaattagatg tgtctggaaa tatggcatct ggatatctta
    47221 tattcataag tatattacta cataatttac cagaaggact agccattggt tcttctttta
    47281 tgtcaactga aagtttaggt attacacttg ctatagttat aggtctacat aatataccag
    47341 aagggttagc tatggcatta ggcttagttt gcaataaaat gaaactaagt aaagttattt
    47401 tgtttactgt aatagctgga ttacctatgg gtctaggaag ttttttaggt gtttattttg
    47461 gaggagtatt tacttctctt ataggagtat ttcttgctac agcaggaggt actatgatgt
    47521 atgttgtatt ggaagaaatt tttccacatt caaaaagtgt gtattgtata attggtttct
    47581 tgttaggtac aatgattgta aattatatat aaaattaaaa tgaaagcagg catacaaaag
    47641 atgaaaacta ttataagtaa tattgatata aataatattg attatgagga aataaaaata
    47701 caagcaaaac ttcttagaga aggtaaaaca gttatttttc caactgagac agtatatggg
    47761 ttgggtgcaa atgcattaga tgaaaatgca gtaaagaaga tttatgaagc taaaggaaga
    47821 cctagtgaca atccattgat agtccatata tatgaaaaag aagaagtata tgacttagcc
    47881 aaagatataa gtgataaagc taaacttgtt atagaaaagc tttggccagg acctataaca
    47941 attatattaa ataaaaaaga tataattcca tacaaaacta gtggagggct tgatacagtt
    48001 gcaataagga tgccttctaa tgttattgcc agggcaataa taaaagaagc tggtatacct
    48061 attgcagctc cttctgcaaa tatctcaggt cgcccatctc caacaaaagc aaaacatgta
    48121 tatgaagaga tgaatggaag agtggatgga atagttttag gaggagacag taattttgga
    48181 ttggagtcaa ctgtattgga tttaacagaa gagactccta tgatactgag accaggaagt
    48241 ataactaaag aagttttaga ggaacttctt ggagaagtaa agcttgaccc atcattaagt
    48301 aaaaaagaag ataatcaaaa agctaaagct cctggaatga aatataaaca ttattctcca
    48361 aatgcagatg tatatataat atctggaaaa agagaaaatg tagcaacaaa gattaatgat
    48421 atgataaaat ctaatagaga caaaggtcta aagacaggtg taatgtgtat tagtagaaac
    48481 cgagagtttt atgatggaga agtaatcgat ttaggaaact ctcttgaaga agttgcaagt
    48541 aatctgtttg atgctcttat agaaatggac aaaaagggtg ttgatgtcat atattcagaa
    48601 gagttcccta agactggagt tggacaagca attatgaata gactactgaa gtcagcagga
    48661 tacaaagtga taaaggctta agagggagtt gtaaaatatg aatatactta ttgtgtgtac
    48721 aggtaatact tgtagaagtc ctatggctga ggctatacta aggaaagcaa ttaaagaatc
    48781 tggaagaagt attgaagaat attctatatc atcagcaggt atatctacag caaatggaat
    48841 gggtgcttct gaaaattcta tagaagtact aaaagaaatc ggtatagact tatcaaatca
    48901 tagaagtaaa gtaattacta aaaaattaat tgatgaatca gatataatac taacaatgac
    48961 taaatctcat aaagaaattt tagtacaagc agttccaaaa tgcaaagaaa aagtgtatac
    49021 ttttaaaggg tttgcaaata aaaatgagga agatatatct gacccatttg gtggaaattt
    49081 ggatatttat agaagcacta tgagagaaat aatgtattct gtcaacgaaa tagtaaaaaa
    49141 aatatgaaac ggaggataaa caaatgaaga taggattagg ctgtgaccat ggaggatata
    49201 atttaaaaaa agaaataata agctatttag aaagtaaagg tatagaatgt gtagattacg
    49261 gaactaataa tgctacagat tctgttgatt atcctgttta tggagaaata gttgcaaatt
    49321 cagttataaa taaagaagta gattatggaa tattatgttg tggtacaggg ataggaatat
    49381 ctttagctgc taataaggtt cctgggataa gatgtgcagt tgtatcagat gtattttctg
    49441 caaaaatgtc aaaagcacat aatgatgcaa atatgttatc attaggcgaa agagttttag
    49501 gaaaaggtct agcacttgag atagttgaag catggattaa tacggatttt gaaggtgata
    49561 gacatgctag aagagtaaac atgattaaat caatagaaga aaaacataat aaataataaa
    49621 aattacagtt ttatcaggag gaattatcaa aatgagcaaa gtggtagaga caaaccatcc
    49681 attaatacaa cataaattaa ctttaatgag agataaaaat actggttcta aagactttag
    49741 agagctttta actgaaattg caatgttaat ggggtatgaa ataacaaaag atataccatt
    49801 aaaagatgta gaaatagaaa ctcctattca aaaaacatca tctaaagtag ttgcaggtaa
    49861 aaaattagca ataattccaa ttttaagagc aggtcttgga atggtagatg gattagtgag
    49921 cttaatgcca gcagcaaaag ttggacatgt aggactatat agagacccag aaacattaaa
    49981 accagttgaa tattattgta agcttcctca agacatagga gaaagagata taatagtagt
    50041 tgaccctatg cttgcaacag ggggttctgc tgtagcagct atagatttac ttaagtctaa
    50101 aggagctaaa agtataaaat tagctaattt agtagctgca ccagaaggta tagcagaagt
    50161 gcaaaaatat catgatgatg ttgatatata tgttgcatca gttgacgaaa gattaaatga
    50221 acatggatat ataattcctg gtcttggtga tgctggagat agattgtttg gaactaaata
    50281 aaaataaata actataaata tttattaggg actttcttat atagtgtata taattttatg
    50341 taagaaggtt cttttttata tattttttct caaaatagga attattgaat tgataaattt
    50401 ctcgaattga gaataaaaag tttttaccaa ttaaaaaaga ttgcttattt tacaaggttt
    50461 tatagaatag tagtctattt taatgtggca tgttagttgc ttacgattaa gattataggt
    50521 attaagtgta ttagttaaat tgagaattga atattaataa tattattggg agtggtaata
    50581 catgaagaat tgtatagtag taagaggggc tggagattta gcaacagcag ttattcataa
    50641 attacacaac agtggtttta aagtagttgc gttagaaata gaagagccat tagctataag
    50701 aaggcaaatt tctttttgtg aggctgttta tgaaaaaaaa gtaactgttg aaggtgtaga
    50761 atgtatattt tgcaatactg aaaaagaaat agaagaagtt ttatctcaac ataaagtagc
    50821 cttgattata gacccaaaag gagaaaaatt atctaaatta aatccaatcg ttttggttga
    50881 tggaatactc gctaagaaaa acttaggtac aactaaagat atggcaccat ttacaatagc
    50941 tttaggtcct ggattttgtg caggagaaga tgtagatgtt gttatagaga caatgagagg
    51001 tcataatcta ggaagaataa taactaatgg tagagcagaa aaaaatacag gagtaccagg
    51061 agcaataaaa ggtttttcta aagagagagt tatgcattca cagtatgatg gcataatgga
    51121 aaatgtatgt aagataggtg atatagttga aaagggagac ctactttgct atattaataa
    51181 ttatgaaaaa aaacatgaag ttagagcaac aatatctgga gtccttagag gtttattaaa
    51241 ggatggagca aaggtaaaca aaaatttaaa aatactagac atagacccta gaaaagaaga
    51301 agttaagaat gcttttacaa tatcagataa agctagatgt atagctggag gggttttaga
    51361 agccatacta aacaatggga tttatcccca aaattaattt atattagata aagctattaa
    51421 tattttatta agatgatata ataaatttaa tagattaaag agagcatatg acgggtattt
    51481 aaaatttaaa tggtaaaaat gctctttttt tattggacat tcaattaaca tgtgtatata
    51541 atataaaaat aagtatttat ttaggttgaa atctaataaa tatataatac cagtacataa
    51601 gcaaagagga gaaaagtaaa ttatgagacc atcatgggat gaatacttca tggaaattgc
    51661 agaagtagtg aaaaagcgtt caacttgtat tagaagacaa gtaggagctg taattgtaag
    51721 agacaaacaa atattaacaa ctggatataa tggttctccg agaaatcttg aacactgtga
    51781 aaatattgga tgtaagaggc aggaattaaa tattccctca ggagaaaggc atgaattatg
    51841 cagagcatta catgctgaac aaaatgcgat aatacaagct gctcataatg gtattagtgt
    51901 agatggggca actttgtatg ttactacaag accttgtgtt ttgtgtgcaa aaatgtgcat
    51961 aaatgcaggt atattgaaaa ttgtttatga aggtgattat ccagatgata tgtctacaga
    52021 attattaaaa gaagcaggaa tagaactcat aaaattttag tggataaaat ttataagaca
    52081 ataaatgtca aattatgaca ctgaaataca atgatatcaa atgattaaaa gaaagtattt
    52141 gaaaaatcat cagattagta gtaagatata ttttataatt aaataaattt atgagataga
    52201 ttaattacat gttatttatt ttataataat gagggatact atttatgagt aaaagaaata
    52261 cacatacaga aattgcaaag ttgtttagtt taataagtca aataggattg atgattgtaa
    52321 tatcaatatt aggatgtact ttcttaggaa aatttttaga tagtaaattg aatactactc
    52381 cagttctgac aataatattt ttattgttgg gtgttggagg tgcttttagt ggtgtttata
    52441 aaactctaat agtatataca cgaaggaagt gatatattgg atataaaatt acttaaccag
    52501 gtaaggtcag taacaaaagg tatagtaata tttgatgtag ttttaattgt gctaatgttg
    52561 ataacatcaa cattaagtaa accagtatta ttaggactta tatttggctc tataatagct
    52621 atgttaaatt ttagattatt ggcgatatca ctggaaaaat cagtgacatt tcctgctggg
    52681 aaggcacaag cttatgcatc agcacaatat gctgttagat tatttataat ggcagttgtt
    52741 ctaattgcat cagctacagt accacattta aatataatcg gaacagcatt gggattattg
    52801 agcacaaagt ttgtcatatt atcaaaaaac tttataaata aattaaagag gaaggaggca
    52861 taagtatgaa tcaagcgcat tattatctca taggaaactt taagattagt gaaacaatac
    52921 tagtaagttg gggaataatg gcctttttag cgatagcatc ttattttttg actagaaact
    52981 taaaaaaagt tccaactagt aaagttcaaa tattcttaga atttgcagta ggtggtcttg
    53041 ctaaaatggt tacagatgtt atgggtaaaa atacagtaaa aagaatgcca tatatgatac
    53101 catacatagg aagcttgttt ttatttttcg catgttcaaa tttaagccca ttacttggat
    53161 taaggtcacc aacaaccgac ttagacacaa ctgctgcatg ggcaatgatt acatttttta
    53221 tgatttattt tgcaggagtt aaatttaagg ggttatcata ctttaaagaa ttggctcaac
    53281 cacttgccat aatgttacca atcaatatta taggtgagtt agctagacca atatcattaa
    53341 gtttccgtcc atttgggaat attttaggtg gaacaataat aatgggtctg ttttatcaac
    53401 ttttaggttt tatatctagt ttaataccag gattatcaat accaattgga gaaatattaa
    53461 taccagtccc attacacttg tactttgact tatttgcagg attgttacaa gcatatatat
    53521 ttataatgtt aacaatggta tttatatcaa gtgcaggaga gttagattaa gaaatcaact
    53581 tatattaaga taaaaataaa ataatttaaa aaattaaagt tttaaggagg aaataattat
    53641 ggaaacagca atagtagcgg cagcatcagc aataggagca gggatagcag ttgcaacagg
    53701 tataggtgca ggtataggtc aaggtatagc agcagctaaa gctgcagaag cagtaggaaa
    53761 ccagccagaa gctaaaggtg atataacatc aactttatta ctaggagttg ctatagcaga
    53821 gtcttcagca atatatggtt tggttatatc aataatactt ctattcgtaa atccattctt
    53881 taaatactta ggaatgtaga tttagtcctt aaatattttg agataggttt ataggtaaat
    53941 catctcaaac ttataatcat gagatgaact ttatcatctc gtgattataa gtagttatga
    54001 tttatggaaa ggaggataat tatggaaaaa gcactagtag gtataacgtg ggaatttgtg
    54061 ttccaaattg ttaatacttt tataatattt ttacttctga gaaagctttt attcaagcca
    54121 gtattaaata taattgaatc aagagaaaat gatattaaaa gtgatttggc agaaggcgaa
    54181 aaagcaaaaa atgaaggttt agctctgaaa aaagaatatg agtcaaaaat caattttgcc
    54241 aaagatgaag gtcaagaaat cataaaacaa gcaactataa gagcagagca gaaatcagat
    54301 gatatagtaa atactgcaaa gaaagatgct cttgatataa aagaaaaagc aaacaaagat
    54361 atagaacaag aaagacaaaa ggttataaat gaaatcaaaa atgatatatc taacatagca
    54421 ctacttgcag catctaaagt tattgaaaaa gatttagata aatctaaaca tgaagaattg
    54481 atagaaaact ttataaaaga ggtaggggaa gctaaatgat aaatgtaata gcaaatagat
    54541 atgcagaagc cctatttcaa ttaggagaag aagaaaattc aactgatgtc ttattcaaag
    54601 aactagaaaa agtagtagat atgatgacta aagttagtaa agatttctac aaagttttaa
    54661 aatcaccatt agtttcaaaa tcagaaaaga aaaacttggt agaaattatt tttagtaaag
    54721 aagtaagttc taacataaaa aactttttaa aagttttagt agataaagat agaatatcat
    54781 atttagaaga tatcgaatta gcttataaag aattattaaa taagaaaaac aatgtaattg
    54841 atggagtagc aataagtgct attccaatga gtgaaacaga tattaaagaa cttgaagtca
    54901 aactttcaaa taaatacaac aaaaatgtta ctatagaaaa tgttgttgac aagactatac
    54961 tagggggagt tctagttaga attggaaatg aacaaataga tggcactgtg aaaactcgtc
    55021 ttgataagat gaaagaaaag ctatctgaag taatatctta agaatggcgg tgaacccatg
    55081 aacttaaaac ctgaagaaat aagttctata attaaacagc aaataaaaaa ttatgagaat
    55141 aaagttgagt tgacagatac aggtagtgtt ttaacagttg gggatggtat agcgagtgta
    55201 tatggattag aaaaagctat gtctggtgag ttgctagagt tcccaggtga aatatatggt
    55261 atggcactta acttggaaga agaagtagtt ggagctgtta tccttggaga tgacagtgaa
    55321 ataaaagaag gcgatatagt taagagaact ggaagaatag ttgaagttcc agttggagaa
    55381 gctttaatag gtagagttgt aaactcacta ggtcagccaa tagatggaaa aggacctata
    55441 gcgtacacaa aaactagacc agttgaatct gaggcacctg gtataataga tagaaggtct
    55501 gtttatgaac cattacaaac aggaatcaaa tcaatagatt caatgatacc aattggtaga
    55561 ggtcaaagag agttaataat aggtgacaga caaactggta aaacatctat agttattgac
    55621 actatactaa atcaaaaagg aaaagatgtt atctgtatat atgtagcaat tggacaaaaa
    55681 cgttctacta tagctcaatt agttagctct ttagaaaaag gtggagcttt ggattataca
    55741 atagtagttt cagcaacagc atctgaatca gcaccacttc aatatatagc accatatgct
    55801 ggagcagcta tgggtgaaga atttatgtac aatgggaaac atgtacttat agtgtatgat
    55861 gatttaagta aacaagctgt tgcatataga gaaatgtcat tgttacttag aagaccacca
    55921 ggacgtgagg catatcctgg agatgtattc tatttacatt caagattact tgaaagagca
    55981 gctaagttat ctgatgaatt gggtggaggt tcaatgactg ccttgcctat aatagaaact
    56041 caagctggtg acgtttctgc atatatacca acaaatgtta tatctataac agatggtcaa
    56101 atatacttac aaccagagtt attctattca ggtgtaagac cagcagttga ccctggtata
    56161 tcagtatcaa gggttggtgg ttctgcgcaa attaaagcaa tgaaaaaagt tgcaggaaca
    56221 ttaaaacttg catattcaca atatagagaa cttgcagcat tctcacagtt tggttctgac
    56281 ttagatgaag atactaaaaa gagacttgct caaggtgaaa gaatcgttga gatattaaaa
    56341 caaggtgagc atcaaccaat aaaagttgaa aatcaagtta tgataatata tgctgttata
    56401 aataatcatt tagaggatat tccgatagat aatatagcta gatttgaatc agaattgtat
    56461 gcatttgtag ataataatta tccggaaata tcaagaaaaa tattaggtgg agaagacttc
    56521 actcatgatt taacagatgc aataaatgaa tttaaagaaa agtttgttgt tgaagtataa
    56581 tcctttttaa aaaaggaggt aaattaattg gcaggagctg gaatcaaagc aatcaaaaca
    56641 cgtatgggaa ctgttgaaag tacaaagcaa ataactaaag caatggaatt agttgcatct
    56701 tctaagctta gaaaagcaaa agaaaaggct gaagattcaa gagaatattt taatacttta
    56761 tacaatacag taaaagatat tgcccaaaca acacgtggaa ttagaaatga atttttaaaa
    56821 gaaagagaag taaaaaataa atgctatgta gtagtagctg gagacagagg acttgcaggt
    56881 ggatacaatt ctaatgtatt aaaggaatct gtctctcata tgaaaggtaa aaaggaaaca
    56941 gtgattactg ttggaaagaa agcacatgaa tttttttcta aaagaaacta caatatagca
    57001 aaagatataa atagtgttga agcttgtgga tatgaagatg cgacagaaat ttcacaaact
    57061 attattgacc tgtataaaaa aggtgaagta gatgaagttt atattgctta tacaaaattt
    57121 aaatctgctt tatcacaaga agttgaaatt ttgaaattgc ttccattagt ctttgaaaaa
    57181 gatacagacg aacaaggaat ggcagtaaaa gaagaaaaac aaaatagatc aaaagtacaa
    57241 tatataccat cagcagaagc agttttaagt tatattgtac ctcagtttat atcaggtaca
    57301 gtatatggtg gaattttgga atcttttgca tcagagcaag gtgctagaag aactgcaatg
    57361 gaatcagcca cagacaatgc gaatgaaatg ctatctaatt tagagttaag ttataacaga
    57421 gcaagacagt cagctgtaac tcaagaaata acagagatag ttggtggagt tgaagctcta
    57481 aaatagggag gttaggaaat ggcaaatgta ggtaaagtag tacagattgt aggagctgta
    57541 ctagatgtta agtttgatag tgaacaaagc ctacctaact tattaaatgc gttagtaata
    57601 aagttaggag ataaagaaat agttgcagaa gttgctcaac atataggtga tgatactgta
    57661 agatgtatag ctatgagtgc aacagacgga cttgtaagag gtatggaagt tgtagataca
    57721 ggagggccaa taagtgttcc tgttggagat gaaactttag gtagaatatt caatgttctt
    57781 ggaaaaccag ttgatgggaa accagctcca aaatctgcac ctaaattacc tatacataga
    57841 ccagcaccgg cgtatgatga actagaaact acagcagaga tactagaaac tggtattaag
    57901 gtagttgact tactagctcc atatctaaaa ggtggaaaaa taggtctatt tggaggagca
    57961 ggagtaggaa agacagttct aatacaagag cttataaaca atattgctaa gcaacatggt
    58021 ggtatttctg tattttcagg agtaggagaa agaacaagag aaggtaacga cctttatggc
    58081 gaaatgagtg agtctggagt tataaataaa acagctctag tatttggtca aatgaatgaa
    58141 ccacctggag cgagaatgag agttgcttta actggactta caatggcaga acattttaga
    58201 gatgagcaag gacaagacgt tttacttttc gttgataata tattccgttt cacacaagct
    58261 ggttcagaag tttcagcact tctaggacgt atgccatcag ctgttggtta tcagccaaca
    58321 ttagctactg aaatgggtgc acttcaagag agaataacat caactaagaa aggttcaata
    58381 acatctgttc aagcagtata tgtaccagca gatgacttaa ctgacccagc accagctaca
    58441 acattctctc acttagatgc aaaaacagtt ttatcaagac aaatatcatc actgggtata
    58501 tatccagcag ttgaccctct tgaatctaca tcaaggattc ttgaccctag tatagtagga
    58561 aaagaacatt atgaagtagc tagaggtgtg caatcaatac ttcaaagata taaagaactt
    58621 caagatataa ttgctatact tggtatggat gaattatctg atgaagataa gttaatagtt
    58681 gcacgtgcta gaaagataca aagattctta tctcaatcat tcacagttgc tgagcaattt
    58741 acaggaaatc caggtcaata tgttcctgtt aaagagactg taagaggatt taaagaaatt
    58801 cttgaaggga aacatgatga cttaccagag tcagcattct tatttgtagg aacaatagaa
    58861 gacgctgtta gaaaagcgaa gggaagtatg tagtcatggc cagtgaattt tcattgaaag
    58921 ttgtaactcc aagtaatact ttttatgatg gagatgttga aatgatagta gttagaacta
    58981 caaaaggaga caaaggggtg ttgaaaggtc atataccatt tgtttcaggt atacctgtag
    59041 gaactttaaa gataaaaaaa gagggaagtt ttaaagaggc gaaaatagca gaaggattca
    59101 ttaatgtaac tcaagataaa actgtcatat tgacagaatc tgctgagtgg atttaataaa
    59161 ttaatttaga gtataaaaag tcattttgac caaaaaaaac ttttgggtaa aatggctttt
    59221 ttgcgttttg gtgttaataa aataacgata aaattgtaag tttttagtga taataaattc
    59281 acaaaatgtt taaatttact gccaaattat gttgtaatta ataagataaa gaagatttag
    59341 atagctttta tgtaagtgaa aaagtcttca tataagaaat acatataaaa tttttataaa
    59401 atttaaaaaa tttgcttagt tgtgtagtat aataaataat ataatagatt tgtatataat
    59461 attcattaca aataatttta aaagttacag ttttattata atgattatta aattaagata
    59521 agtaacataa actaaataat aatgtgtatt atcgatagta aatttataaa ttcattatta
    59581 attattgaaa gaagtattat aaattttctg gaggaacaat gaatatattt gatattggcg
    59641 tagatataat tgaaattgat agaataagaa aggctgtaga caaaaataat aggtttttgg
    59701 agaagatatt tacagataga gaaatagagt attttaattc taagaatttt aaagcagaaa
    59761 gtatagcagg taatttcgca gccaaggaag ctataagtaa atctataggt acaggaatta
    59821 gagtgtttaa ttttaaagat atagaagttc tcagaaatga aatgggaaaa ccaatagtaa
    59881 aaacttataa taatctagca aaaatgtgca tagattataa tgttttagaa ataaaagttt
    59941 caatatcaca ttcaaaagat tatgctatag caaatgcgat aaccataatt aaggactaag
    60001 gagtgattac attatgatgg ataaaacagc aaaagaaata atgacaacag atgtaatagt
    60061 agcaaaacaa gatgatagta tagcagatgt agctaatatg ctaattgcag aaaaaatagg
    60121 aggtctgcca gttgtagatt cagagaatag agttgttgga ataatttctg aaacagatat
    60181 tcttaaaaaa gaaaaatata tagaagcacc tctctatata aatctattac aaggattgat
    60241 tttcttagat gacttaaaaa aagttgaaaa agatataaaa caagtagctg cttataaggt
    60301 tggagaactt atgtctaaag atataataaa ggttcatgaa gatgataagt ttgatgatgt
    60361 ggctaatgta atgattaaaa aatcaataaa cagagttcct gtagtagatg atgacaacaa
    60421 acttaaaggt ataatttgta gatatgatat aataaaagct ttatacaatg aataaactga
    60481 agtaggaggt gtgatgtgag aaaaaagtgg accatagtat gtattatgtt cttggcactg
    60541 gttataattg taataggatg ccaaaaacga cagtccacaa aagaagaagt atacaaagat
    60601 tttcaaaagc agatttctga tatgaattat tacagttgta aagctgaagt agaagtagtt
    60661 ggaaataaaa gtccacacaa ttatgtttta attcatactt ataaaaaaac cgataactat
    60721 aaattagaag taatttcccc aaaacattta aaagggaaaa gtatagaata tcaaggtgat
    60781 aaaatattag ttaaaaatcc aaagattagt gatgtagtgg agttacctaa tacaggaaaa
    60841 aataatcaat atctttttgt aggagacttt ataaaaaact atcttcaaaa tgaggagatg
    60901 aaagtaaagt tatcgaaagg acatttggtt ttagagactt ttattcctgg ggataataaa
    60961 tattttaaca agcaagtatt atatgtaaat gctgacacaa aaaatcctga aaaaatggaa
    61021 gtgttagata aagagggagt gccaagattt acagtaaaat acaaagattt tgaatacaga
    61081 aactaagggg gactaaagac atgcaaaaaa taacagtgcc tacatgggca gagataaatc
    61141 tagataactt aagatttaac ttaaataata ttaaaaattt attagaagaa gatattaaga
    61201 tttgtggagt aataaaagct gatgcatatg gacatggtgc agtagaagtt gcaaaattgc
    61261 tagaaaaaga aaaagtagat tacttagcag tagcaagaac tgctgaagga attgaactta
    61321 gacaaaatgg cataacactt cctattttga acttgggata tactccagac gaagcttttg
    61381 aagattctat aaaaaataaa ataactatga cagtttattc tttagaaaca gcacaaaaga
    61441 taaatgaaat tgcaaaatct ttaggagaaa aagcctgtgt tcatgttaaa atagactcag
    61501 ggatgactag aataggtttc caacctaatg aggagtcagt acaggaaata atagaattaa
    61561 ataaattaga atatatagat ttagaaggta tgtttactca ttttgctaca gctgatgaag
    61621 taagtaaaga gtacacttat aaacaagcta ataattataa atttatgtct gataaattag
    61681 atgaggctgg tgtaaaaata gctataaaac atgtatcaaa cagtgcagct attatggatt
    61741 gccctgattt aagattaaat atggtaagag caggaataat attatatggt cattatccat
    61801 ctgatgatgt atttaaagat agattagaat taagaccagc catgaaatta aaatcaaaaa
    61861 tcggacatat aaaacaagtt gaaccaggtg taggaataag ttatggacta aaatacacaa
    61921 ctacaggtaa agaaacaata gctacagttc caataggata cgcagatgga tttactagaa
    61981 tccaaaaaaa tccaaaggtt cttattaagg gagaagtgtt tgatgtagtt ggtagaatat
    62041 gtatggatca aataatggtt agaattgaca aagatataga cataaaagtt ggagatgagg
    62101 ttatactatt tggagaaggc gaagttacag ctgagcgtat agctaaagac ttaggaacta
    62161 taaactatga agtgttatgt atgatatcaa gaagagttga ccgtgtttat atggaaaata
    62221 atgagcttgt acaaataaac agttatttgc taaaataaaa ccatgatatt ataatctggg
    62281 aggcgatttt gtgtacgata agagtaaaga aaaaatagaa gttactttac ctgactctct
    62341 gatttctgaa gttgatagta tagttcagat ggagaacagt aacagagaag attttgcaaa
    62401 agctgctttt cagttctata taactcagaa aaagaaaatt catattaaag aatctatgaa
    62461 aacgggttat agagaaatgg gtcaaattaa tctgtcacta gctgaattag gtatgacagt
    62521 tgaagaagta tcttctgatg ataaaaatga agggaagatt gcccaaggtg agtactaatt
    62581 gtgaaataaa gcgtggtgat ttatattacg ctgatttaag tccagttgtt ggttcagagc
    62641 agggaggcgt tagacctgtt ctgataatac aaaatgatgt aggtaataaa tatagtccta
    62701 cagttatagt atcagctata acatctcaga ttaataaagc caaattacct actcatgtag
    62761 agataagttc caatgaatat gggcttaata aagactcagt aattctttta gagcaaatta
    62821 gaactatcga taaaaagaga ctgagggaaa aaattggttg tctagatgaa aatatgatga
    62881 taaaagtaga tgatggactt caaataagtt taggattgtt tactttttaa agagggattt
    62941 gtcttttatt agacaatccc ttttttcttt taaatatctc ttaaggttta attttaatgt
    63001 actatgttaa taaaattaaa aataacgcaa aaaaatagca taaaagtgat ataataatat
    63061 ggaattgata taaaattacg aactcaaggg aggtaattgc atgagagacc ataaaggatt
    63121 aaatgagatt gcgcgtatca taagaagaga tatagtttca atgatacata gagccaaatc
    63181 tggacatcca ggagggtcat tatcagtagt tgaaatactt actgcgttat actttgatga
    63241 aatgaatgtg gattcttcaa atcctaaaat ggaggataga gatagatttg tattatcaaa
    63301 aggacatgct gcaccagcat tatatgctac attggctgaa aaaggctatt ttgataagga
    63361 agaactgaat ggattaagga agataggaag gatgttacaa ggtcatccag acatgaaagg
    63421 cacgccaggt gtggaaatat ctacgggttc tttaggtcaa ggtttttcag ttgcatgtgg
    63481 tatggctatg gcatcaaagt tggataatgc tccgtggaat gtgtatactt tgcttggtga
    63541 tggtgaggtt caagaaggaa ttgtttggga agctgctatg agtgctgcac attataaact
    63601 tgataattta attgcttttt tagataataa tggacttcaa atagatggag atatagaaag
    63661 cgtaatgagt ttaggttcaa tagttgataa atttaaagct tttggttgga atgtaattga
    63721 gatagatgga catgattttg accaaatatt tgcggctctt gatatagcta aatcaacagt
    63781 taaaaaacct acaatgatag ttgcaaaaac tataaaaggc aaaggaatat cttttatgga
    63841 aaatcaagca ggatggcatg ggacagctcc aagtgatgag gagctagaaa aagccttgct
    63901 tgaattagga ggtgctgaca atgagtaaaa tggcgacgag agaagcatat ggtaaagcat
    63961 tagtaaaatt aggtcaaata aatgacaatg ttgtagtatt agatgcagat ttatcaaagt
    64021 ctacaaaaac acatgatttt tacaagtcat ttccagatag attttttaat atgggtatag
    64081 ctgaacaaaa tttaataggc gctgcttgtg gattatcaac tgctggtaaa ataccttttg
    64141 caagtacttt tgctatgttt gctacgggaa gggcttttga gattataaga aattcagttt
    64201 gttatccaaa gctaaatgta aaaatatgtg ctactcatgc aggtcttact gttggagagg
    64261 atggagcatc tcatgaaagt gtggaagata ttgctataat gagagctata ccaaatatga
    64321 cagttcttgt tccagctgat ggagttgaaa cagaaaaaat tatttttgaa atagctaagt
    64381 ataatggacc tgtttatgtt agattaggga gaagttcagt accagtttta tttgatgaag
    64441 attataaatt tgaaatagga aaaggtacag tcttaagaga aggaaaggat gtatcaatta
    64501 tagcttgtgg aattatggta aatgaagctc tattagcaca agaaaagttg caagaagaag
    64561 gtataagtgc tagagttata aacatgtcct cgataaaacc tatagacaaa gatttaatat
    64621 tagaatcagc aaaagaaacg aatgctattg taactgtaga agaacatagc ataattgggg
    64681 gattaggttc tgctgtaagt gaggtagtag gagagtcttg tccaaccatt gtaaagaaag
    64741 ttggaattaa agatacattt ggagaatctg gtactccaaa tgaattgtta aaaaaatatg
    64801 aattaacttg tgatgacata gtaaagactg ttaaagaagc tattattgca aaaagaatgt
    64861 aagagatata aattattcat gtttgttaat aatataatat atttaaaaga gaggtataaa
    64921 gtgttatatt aatttatatc tctctttttt ttatatgata tcaatatatc aaaaatgtaa
    64981 taaaatattc aaatttttac aaaaatagag aaaatattca aatatatatt gactattcag
    65041 aaaaatatga ctaatatata atttatagag aaactaattt tatatataat gactacttag
    65101 ataaaagaat ctaaaaaaat tatgagagga ggagtagggt ataaaatcag attataagtt
    65161 ttaagttatt atactaaaaa gctataaaac agttatcatg tattttatgt taaaggaaat
    65221 tgtaggtagt ttatcgaatt gtttaatcag aagaaaaaat ttcacatggg gaggtaactg
    65281 agatatgtca gaaaaagtaa atgttaaaac agtcatcagt ttcgcaggtg cgtatgtagc
    65341 aacagtaatc ggttctggat ttgcaacagg acaggaaata atgcaattct tctcttttta
    65401 tggttttgca ggtattattg gtgggataat ttcaatggta ttattctcat ggatgggtgc
    65461 ttcagttatg tcaaaaggta aagagcttca acttaaagaa cctatcaaaa tttatcgtgt
    65521 ttattgtggt aagtatttag gaatattctt tgaatggttt ggacctttat tcttatttgg
    65581 tgttttcgta gtaatgattt caggagcagg agcaacttta actgaatact atggattaaa
    65641 tccatttgta ggtagagtag gtatggcagt agtagcatta ttaactgttt cactaggtct
    65701 tgataaatta tcaaagatac taggtggaat agggcctata ataataatct ttacactttt
    65761 agttggtggt ataagtttag ctaaaaacat aggtaatata ggagaagctg cacaagttct
    65821 tagcactgta aagatagcta aaccagttcc aaatgcctat ctatctggtg taatatatac
    65881 tacttataac acaattgttg ttatggcatt cttaactgga ttaggagcaa gtgctgctaa
    65941 caaaaaagaa gctatttgtg gtggtatatt aggtggagta gcacttatgg ctgcagctat
    66001 aatgatgcac ttagctattc tttctgatat aggaaactta tattcaaaag caataccatc
    66061 attattctta gcagataaga tttcaccagt aattggagtt ttattctcaa taattcttat
    66121 attaggtata tatacaacag ctgtaccttt attatggtca gtaactaata gatttgtaga
    66181 tgataaacat cctaagttta aattaataac tttaatagca gctatattag gtcttatagg
    66241 tggcttccta ccatttgata agctggttgg tattttatat ccatatactg gatatatggg
    66301 cgtcataata ctggtttgtg ttctttatag acagattaca aaaacatctg gatatcaaga
    66361 aggaatcagt gacaaataag tattttttaa tattgtaaac tcaagagcta tatgaaaaca
    66421 atgaaaatgt tttcatatag ctctttttat tttttagctc gtttattatg aaatagaaaa
    66481 aacatgtttt ttagttacat tacatatatt tataattatg tataaatata tactaatcaa
    66541 taatttagag tctaagataa gtttataaat catatattta gaatatatgg gaggagtgat
    66601 aagattgaat gtaaagttta atattaaagg tataatttat ggagttatag ctcttgtatt
    66661 cgttataggg ggatttatat tcataccaag tatgtttgta gagaaatcta aacccataga
    66721 ttatacagta ttacaaagaa attcaatacc agaaaagata ttagatgtga tggataagta
    66781 tacaaatgaa gaaagagcat tagcggctaa aatcgataac aaaatataca ttatagtgac
    66841 tagaggaaat aataaatatg gtatagaaat ggacaaaata gaaagtgtgg ttgaggaagg
    66901 aaaggatgtt ttgagagtca agataaagta taaagataag gaagattctt ttccatacat
    66961 agttgttgaa acaaatatga gtgaacttcc agatagaata gaattaaatg cgacgaaata
    67021 agaaggtatt ttataattaa ataactgcat attgtacaat aaagtcatgg tttttattaa
    67081 tgtaagtaaa ttgtgtatgg ttcttattgt tgtaaaagcc atgacttaaa atgcttataa
    67141 agtaagatat taacagtagt atttattact acattaaatg gggtctggaa atacttaata
    67201 ttctaactat ttggagtgat aattctagtt tcagtaacta tgtagtctaa ttgtgcatca
    67261 tgagtttctt ttggaataga atcgaatatc tggaagtcaa atgctatgcc gatagttata
    67321 gcatcttttc ttaagttttc taaaaatcta tcataaaatc ctccaccata tcctaatcta
    67381 tagcaatgta tatcatatgc tacagctggt acaattacaa catctaaggc cttaatatca
    67441 attgtaggtg atttttcgtt aggttctctt attccatatg ctccaattct caatccctct
    67501 tttaaatctg ttatttgagt agggattaat gtatgatttt cttttattgt gatgggactt
    67561 gatactattt tctttagaga caaaagtttt ttgattaaat tatctgtttg aacttcattg
    67621 ttaaaattta gataaagcat tatattagtt gcatttctta tatcttccat ttgaagtaat
    67681 ttttcagtta ttaaatttga attactaagt acaaagtttg cactcttatt ttttcttgat
    67741 tcaataactt tttttctaaa ttcttttttc ataaaataat tcctccctta atatgttata
    67801 atgtgtacag caattgtatt taatataaat tttagtataa tttattgtaa taaagcaata
    67861 tatttgggta aatgtaataa aaataacagc tagtcatata ataataatag tttatgtaaa
    67921 aggagatgta tcttgtgatt tcaaagaaga aagctatttt tttaggggtg attttagtaa
    67981 ttataacagc tatggttaca tcagcatttc agttgacatt ggggaataaa gttgtaatat
    68041 cgaaagaact ctatgaagac tataaaaaat atgataagtt gttaggacta gaatctatca
    68101 taaaacaaga tttttataaa aaagtatcag atactgattt ggtaaatgga gcatcaaaag
    68161 gtctatttct aggaacaaat gataagtatt ctggttatta tactaaagat gaaatggaga
    68221 atctaattaa tgatagtgaa ggttcttatg ttggtgtagg tatgtatata ggggcatcaa
    68281 aagatggtgg cttagtagta gttcccatga aagattctcc agcagagaaa gcaggtgtaa
    68341 aatcagggga taaattagta aaagtcaatg gaaaatctgt ctcatataaa aattcagatg
    68401 aagctgttcg tatgatgaag ggtaaaaaag ggaaaatagt tgaactgact atattaagag
    68461 aagataaaca attgaacttt aaagtaaaaa cagaccagat aattgagaag agtatagaaa
    68521 gtaaagtaat tgataatgat ttaggatata tagaaattac ccaatttata tcaagtacat
    68581 atactgactt tgataaagct ttaaaagaat taaaagcaaa aaatatcaag ggattagtaa
    68641 tagaccttag aaataatcct ggtggaatgc tagatatatg taaagaagtt gctgatgagt
    68701 taattggtga aggaactata gtatatacaa aagataataa gggaaatact gagtacttga
    68761 aatctgataa agaaaaattg ggacttccaa tagtagtgtt aactaatgga gaaagtgctt
    68821 ctgctgctga aatattaaca gctgcaatcg ttgataataa agaaggtatt tctgtaggga
    68881 ctacaacttt tggtaaaggg ttggtacaat cagttgtaag attgaaggat ggaacaggat
    68941 acaagctaac tactgctcaa tattttacac ctaatgggga ttatatcaat gaaaaaggta
    69001 taaagcctac tattgaagag aaagatgaaa ataaacagtt agatgtagca actaagtggc
    69061 ttagagaaca gattgataaa taaaatttaa tttttataaa tttatattgt aaaataaaga
    69121 accttaataa aaggagtgtc tcaaaattaa ctttttaggg tctttaaaat aaagtgtgta
    69181 ttcttctaaa aagtagtgat aattgaaata ttaaatatca ctatataaag gaaggtgcac
    69241 actttttatg cttaataaaa acaaaatatt aaaaaactta ttgaagaata tgatgttaaa
    69301 acaactacag atattcaaga tatgcgaaaa gatttatttg caagtacaat tcatcaaatg
    69361 ttagaagtat agcttgatga ccatttaggt tatgatagat atgacaataa gaataaaaat
    69421 actaaaaact ctagaaaggg atatagaaat aaaaatatta aatcagattt tggagaaata
    69481 actttaaata ttccaagaga ccgaaatgga gattttgaat taaaggtaat tagaaattat
    69541 gaaaatgata tatctcattc tctaatagat aaaattactg atagagttat acctttagct
    69601 catttaagta tttattttga agaaaaaatt taaaatctaa gttaataaag aaatatttca
    69661 aaaaaattaa gaaattttct taaaggagta ataatttttg caaaaataaa aaaacatcaa
    69721 agtaaggcta tgatttttaa aggcatagcc ttactttgat gtttaattat tacttaaaga
    69781 ataaattttt atttgtagtg aaaactccgt agattctatt aacatgtata cagcaggttt
    69841 ttgctttaat ttatttagag tcacgcaata tctatatcat gggtaccacc atagttgtat
    69901 aggaagttat ttcaccgaat ccttttctta ctttatcgta tattatattg ttgtattatt
    69961 cttaacatta gtctaaagta ctttctataa tttactaaat tcagtttgca agttattggc
    70021 ttgttcttta aggactttaa ttaaatattc ttctcctttg tgcattaatc gattgctagg
    70081 accagtaata ctaatagcac atattaaatc attattgcaa tcaaaaatag gaactgcata
    70141 acaagacaat ccatattcat actcttcatt gtctattgat aaatttagtt ccagtattct
    70201 ttttttagct aacagaaact cgttatactc tgtgattgta tttacagtac gcttttctaa
    70261 gttattaaag taatcttgaa gaaattcttc ggattcttga cttaggaata atttccccat
    70321 tcctgaacaa tacaaaggac taacaggtat aagggttgtt tgtaattgat aaaactctcc
    70381 ttctattgat tttacaataa taacttcatt ttgataacgg atacctagat ttacggattc
    70441 tccagtttct ttgctgattt tttgcaaata gggttctgct acagaaatta atttattttc
    70501 ttggcttgtt cccttcgcat aagataataa acgataatca agagtatagt cgctgttttc
    70561 taattgcttt ataacatgaa tctcttcaag tgttttaact atacgaaaga cactagtctt
    70621 aggaatagat aatatttctg aaattttagc aatacctata cttccttttt cattaataac
    70681 atcaattatt ctaaaactat caactatgtt cttgataata ggactcttct tctccataat
    70741 tgcccaccac ctttctttta aattctaagt ctaattagtt aaaatggcaa gacgtatttt
    70801 caaacttcat atatgtaaag ctcactaatt attagtattt tttcactaat tttagttgtt
    70861 tctttataaa aaagagataa aaacaaaaaa actttgttat ttattattaa aggtattgac
    70921 tatatgattt tataatagta ttataatttt ggaacgtgtt ccgaaattat aaaagggggt
    70981 aataaaatga aagttagtat tattggtgca ggtgctgtag gtgctacaac tgcttttaca
    71041 cttgctaaaa caagttttgt agatgaaatt gcaattgttg atattgatca aaaccgtgca
    71101 aaaggaaatg cattagatat tcttcatgga ttatctttaa tgcatgaaac aagaattgtt
    71161 tcaggtgatt atgattgtgc aattaactct gatgttattg taattactgt aggagtacct
    71221 gaaaaagttg gcgaatcacg tttggttcca ttacaaaaaa atgtaaagat acttcaggat
    71281 attataccaa agatcacaag tacgagtcct aacggattat tattggttgt aagtaaccca
    71341 gtcgacatca taagttactt ttctcaaaaa atttcagggt gggaagcaaa acgtgttatt
    71401 ggtttaggta caacccttga ttccgctcgt ttaaattatt taatcgctcg tgatttaaaa
    71461 atttcacaaa ctgatattca aggtttagta attggtgaac atggtgactc tcaagttgtt
    71521 gcttggagtc aaacaagtgt taaaggaaca cctttcttgg attatgttaa atctaataac
    71581 atctcgttac aagaagatta ctgtaataat ttggctcaag aagttaaaga tactgcgttt
    71641 gatgtatggg atatgaaagg accaaattgt tactgtgttg ccttggcaat tgagcgtgta
    71701 attaaagcaa tcgctcgtaa tgagcatgca attttaccag ttagtcagcc agctgattca
    71761 gaaatgtata tcagccagcc tcatataatt ggacgtgatg gtgtacaaag aagagttatc
    71821 ttatcttatg atactcaaga gttaaatgca tttgatacgt cttatcaatc attgcaagat
    71881 attgttaaac aaattgaaat ttaattaagg gagaaggatt tcatgaatat tagtcaaaca
    71941 aagggtttct ttaagttcct tatcttaact ttactaggta ttgtattttt attgattcca
    72001 tttcggttcg aaaatggcat ggatacaata ttatttcact atctaaaatt atttatttca
    72061 gaaaatcatg ctgttattca aacaattgta gtcttgttgg tttgtcttag tgcaacctta
    72121 tctcttatag atcaattgtt accaaatacg attttacgta aacaaagatt acttaagaaa
    72181 ctgttctcaa cgacaccttt ctatgtattt aatagaatca tgggtgtaat tattgctatg
    72241 ctttgttatt tacaaatagg tcctaaattc atcatttcaa tcgatactgg tggcgcaatg
    72301 cttgatttag gaacacaact ttctgtactt gtaccattga tgctactatt tcaaacactt
    72361 attttagagt ttggtgctat ggagttttta ggacaattga tagggtttat tgcaaaacca
    72421 ttatttaaac tttcagaaat ttgtgctgtg aatataatca gtgcctgggt tggtcctggt
    72481 aatgctgcaa ttattggtac taaagaactt tttgaaaagg gatactttac agtaaaggaa
    72541 tccgctgtta tcggaagtca gttttccatc tcaagtattg gttgggttgt actggtttgt
    72601 taagttttag acacaatgga tcattttgct ttaatattct taggaataac tctgataggt
    72661 ataatcttag ctttcataaa tgtaagaatc ccacctattt ctaattatcc tgatacttat
    72721 gttgatggtt caacaacttc taaaattgtc tctagcacac aagggacacg actgcaacgt
    72781 gctattatac aatcaagtat gcgtgcaaac caagttactt taaaaaattt tacaagtaag
    72841 attgataata tgagcttcta tgttttatgg ctaacaccta ttattatttt ctggggggca
    72901 ttagcactta ttgtttcatt gtatactcct ctattaactt gggtatctta tccaatagaa
    72961 ttagtattga agttagcaaa tatctctgaa ccagcaatta ctgctagcgc aattatgtca
    73021 ggatttgcgg ataactattt accagttatc ttgggcaaag gattagaatc cattgaaagc
    73081 aaaacaatca ttactatgat gagcatccta cagcttatct ttatgtcaga aatcgcaaca
    73141 ttacttcagt catgtaaagt tgtaaaaagt tttaaagata ttattattat atttttacaa
    73201 agaactatta tcgccctacc atttgtaatt atatttacaa agcttattct ataagattta
    73261 aaggttttaa agtgcttgaa tgattattct ttaatagtct ttcttttcat aatttagatt
    73321 gatgaacatt ccttgaaata tcttttgtat aagggagttt gctaaaatat attgttaatt
    73381 ttttaatatt tatttaattt cttatttaaa gaaattttga agtcatcact tcaaatagtt
    73441 atattgaata ttctatttat ttttgtgatt ttcaaactat cattatgtaa agcattatat
    73501 agccaacctg gatatctaat tgaatttgtt aaaaattaaa tttataaaga taaaatatgt
    73561 gaattatatt aaaaatatac ataagtagaa gatatagggt tggtaattct aatattacaa
    73621 gccctatttt atattattta tggagtcttt aaaataaagt gtgtattctt ctaaaaagta
    73681 gtgataattg aaatattaaa tatcactata taaaggaagg ttcctacttt tagtttatga
    73741 ggcactcttt ttgtatgaaa tcaaatgtat tttcatcatt ttaacaatga aaaagaggct
    73801 tatctctatt tttaggaagc ctctataact ttatattgaa tctatttatt aactttgtac
    73861 atacatatac cacttatata agtttcgtat atattaaagt ccttatctgt tactataaaa
    73921 tctgcctcca taccttgatg tatggagcca caaacattat caatattaca acttaaagca
    73981 gggatatatg tagccatttt tattgcatct tctaaagtgg ctatgttcca atcaactata
    74041 tttctcacag ccttgtccat agttaataca cttccagcta aactcccact atttaatctt
    74101 gcaacactat tttttacatt tacattaaac ttaccaagag tatattttcc atcctccata
    74161 gcaccagctc tcatacaatc tgtaattaaa gctatgttat tactagactt agcatccatc
    74221 attattttaa cagctattgg gcttacatga tgaccatcac aaattaattc agcataagta
    74281 tcttttagta ccatagcagc cccaaccatt ccaggttctc tatgatttaa aggactcatc
    74341 ccattatatg tatgtacaaa cactttagca cctgaattaa cgacttgttt aacttgctca
    74401 aatgtagctg aactatgacc aagagaaact gatatattat ttttagttgc atatcttgtt
    74461 aattctattg aacctttacg ttctggagca attgctattt ttcttattaa atttttcgat
    74521 tttttttgcc ataattttaa tatattgatg tcagggtttt taaaatattt ttcattttga
    74581 gcgcccttat atttttctgt aaaaaatgga ccttctaaat aaatcccttg tatttttgca
    74641 ccctcaactc gattgaagct attgcttata ttttctacag aatcacttag tgtatctaca
    74701 gaatcagtta aagttgtagg taggaaagat gttactccat attttaataa gccttttgaa
    74761 attgtgttta ttgcttcaaa tgtattgtcc atgacatctg cacctaaaag accgtgaatg
    74821 tgagtatcaa ctaagccagg agcaatatat ttacctgaaa aatctataac attatcagta
    74881 acattaggtc tttcttgttg aaattcaccg aatttgccat taattatact aaggtaacct
    74941 ttttctttga ttccatgttt cataaaaaat ttatctgcat aaataaaact tttcaaaata
    75001 acctccttat aattatacta tcattgtggc attgacgctt ataatatcat tctgttttct
    75061 tgaaagttat ttaacttact atcttacatg tcttactcta tatacaaatt tatcgcttct
    75121 agcgacactc aaagtaaatt caataactat attgtcatca ttatatgtgg tacgaagtaa
    75181 tttcagacaa ggtgaatctc ctggtacttc caataactta gcttccttat cagagattat
    75241 tccagctgaa aattcttcat cagcaacttt aataatctcg ccataatctt ctctaaatat
    75301 ttcatataaa ggtttttgtt cgattttttc ttttgtcaat cctataaatt ctttcatagg
    75361 aagatatgtt ctttcaagca tcataggaag gtcatcagca agtcttaaac gcattatttt
    75421 tatcattttt tcaccaggag ttatacctaa tttttcagag aaatactttg tactttctac
    75481 tacctcaaat gataatacct ttgtacctgg cttttttcct tgtgttctca tataatctgt
    75541 aaagctataa ctttccatta agttttgaga attttgactt agtgcagcaa caaaagttcc
    75601 ttttccatgt cttttgtata tatatcccat atgctctaac tcagccatag ctagtctaac
    75661 tgtggttcta cttactccat attcatcaca aatttttctt tcggaaagca ttctatcgtt
    75721 tggttccatc tcattttcaa tcttagttct taatatctca acaagctggt catatattgg
    75781 tcttttatca tttcttttta tcataaaaat atagtccttt ctaagtggtt attaccacaa
    75841 tttgattata gaatatagaa ttatttatgt caatgaataa agtttaatca aaattcaata
    75901 agtaaggcta ttaatttatt ataaaattat ggtacattga caaaacaagt aaaataattt
    75961 atattcaaat tggtaataac cactttggat atattatatg aggtattttt tattttacag
    76021 attaatttat tgtttagaaa agtaaaaatt aataatgagg agaatctagt atgattacag
    76081 taataacatt caacccatct atagatagaa tgtatagagt gaataatata aacataggtg
    76141 aggtgcaaag ggtagtaagt aagaatgcaa ctgctggagg taaaggatta aacgtagcta
    76201 aggtatgtaa aattttaaaa gaaaatcctt tagctatggg atttctaggc ggatttaatg
    76261 gagaatttat aaaaaatgaa cttagaaaac tagatataca aaataaattt acaaaaatag
    76321 agcaggaaac tagaaattgc ttaaacataa ttgaggacaa taaagttagt acagaatttt
    76381 tagaaaaagg accaatagta gaaaaaagcg atttagagag atttgaaaat gatatagagg
    76441 aagtactaaa aaatactaaa atactggtag cttctggtag ttattgtgag aatatgccga
    76501 tagactatta tgaaaagata ggaaatatat gtagagcaaa taatataaag tttatattag
    76561 atacatcagg agaagcatta aaaatagctt taaaatcaaa accatattta ataaagccaa
    76621 atatagatga aataagacat ttattaggaa tgaatataga atcaagagaa gaaattatct
    76681 tgtcaggaaa aaaacttatt gaaatgggtg cagagaatgt atgtatatct ttaggaaaag
    76741 atggtatggt gtatttaaac gaagataatg tatatgatgt aaaagtacca gttgtaaagt
    76801 gtataaatac tgtaggtagt ggagatagca cagtggctgg atttagtgta ggtattttaa
    76861 ggggttataa aatagaaaat ttacttaaat ttgcaaatgc ttgtggtata agtaatgctt
    76921 taaatatgga aactggattt gtagatttgg tagaaattga taaatatcaa gatttagttg
    76981 aagtaaaaaa gttaagttaa atacatttaa tgggaatata ataaatttaa tgttgttgta
    77041 atagatttta attttaatat aaaagatata gtcttatata aaaataggtt agaaaaattc
    77101 atttttaacc tatttttata ataaatatct attttactga atttataatt ttctctagta
    77161 atctttgagc cttgatacac tcttctccat taatagctgg ttttatatta ttttctatac
    77221 aatcaataaa atgatttgat atatcctcaa aacccttttg ttttaatatg tttacccatg
    77281 caccactttg ctttaaagtt aggtttccac cttcttctat ttccagtaca ttaagattct
    77341 taactctttg aatattaccc tttgaaagaa tttcaacttg ttctaacttt gttccagaat
    77401 ctctatgcat agaggtgttt atagagaaat ttttaccttt aagtttatga cttacaaata
    77461 taagattctt attgtctgtt aaaaataaat cctctccact aatttcaaca tcttcatttg
    77521 ctaaccataa agcagtgtca ataacatgta tatagtcatc tataagagta ctgtcgaatt
    77581 taacatttct taaggaattt aatccatgtt tacatatatt gatagataca atttctgtag
    77641 cattattttt aatttctttg tacataggac agaatctacg gttgaatcca accattaaat
    77701 ttaagttttt tttcgtactt aattcgataa gttcttctcc ttgacttact gttgaagcaa
    77761 gaggtttgtc tacatataca tgaacaccta aatttaataa tatttttata atttcgtagt
    77821 gtgtttctgt agagctatgt agaaaaatac aatcacattt tttagctagg gattcaatag
    77881 aatcgaatgg catgattcta taatcactac agactttttc ccttttaact ttatttggag
    77941 taaaagctcc tacaaactca aatctctcag acttagttaa tataggtaaa tatgcctttt
    78001 gagctatgga gccaagacct atcattccca tttttatatt tttcataata ctttctccta
    78061 aggtttttat atttacagaa ttgattataa ttcagacaca taaatttgta aactttgtat
    78121 taaaaaataa atttaaagct tatataagta aattagcgaa ataagaaata ttgataaagt
    78181 aattttgtag gatatccata aaattgattg atataaatat tttatgtatt gacaaaaaat
    78241 tcaaattaat ttatatttgg attagtggta attaccactt tggtctgaac aagtttttat
    78301 cgtaaaataa aaatactaaa gtatatagag tatgatttta ttaaattttt aaagataaac
    78361 tataaaatta attaaaatct atagtgtata ttttatagtg agtttaagta gtactaaaaa
    78421 atctaagcaa aaaattataa aagagtatat ttttttatag tttaaagtgg ttataacctc
    78481 attaccaaat gtaaacgtta caagtatgaa aggagaatga aaatgtttaa attagaagaa
    78541 caaaaactaa aagatttagg tgcaataata acaactaatg aaataaaaca acagcctgaa
    78601 ttatggttag aaacttatga aatatataaa tctaacaaag aaaaattaag tagattcata
    78661 gatacaataa gtaataatca tgggcagttt agagttatat ttacaggtgc tggaacttca
    78721 gcttatatag gaaattcaat acttccttac cttaaaaata aaaatgacat aagaaaatac
    78781 atatttgaag caatacctac tacggatata gtttcaaacc catatgatta cttaaaaaaa
    78841 gatataccaa cattattaat ttcatttgca agaagtggaa atagtcctga aagtttggct
    78901 gctttaaatt tagggaataa gattgtagat aatttttatc atttagctat aacttgtaat
    78961 ccagaaggag aactggctaa gatgactaaa aacgacgaaa ataattactt gttattaatg
    79021 ccatcaaaat caaatgatga aggctttgcc atgacaggaa gtttttcgtg tatgatgtta
    79081 tctgctatgt taatattcga tagtttagaa gatgatgtag aaaagtcata tataaatgca
    79141 ataattgaaa tgggaagaaa tgttatagat agaaaagatg aaatacatga gttaataaat
    79201 aaagattttg atagagttgt atatttaggt tcaggaggat taggtggttt gacacaagaa
    79261 gcacaactaa aacttttaga acttacagcc ggaaaaatat ctacagtgta tgattctcct
    79321 atggggttta gacacggacc aaaatcattt attgatgaaa atacacttgt atttgaattt
    79381 gtatctaact gtttatatac aagaaaatat gatttagatg ttttagagga gataaaaagg
    79441 gataaaattg ctaaattcac ttgtgcagtg tcagtagaaa atgaaaataa cttctcagga
    79501 acaaagtttg agtttaaaga aaagtataat aaattaccag atgtgtatct tgcaatgcca
    79561 tacatattgt ttgcacaaac tatagcattg tttgtatcgg taaaggttgg aaataagcca
    79621 gatactccat cagctacagg aacagtaaat cgagtagtaa aaggtgtaac aatatatgaa
    79681 tattaaaaga taagattaaa atattataac taaataattt gggagggtat caatgtggca
    79741 ttagtaacaa caacatcaat gcttaaaaag gcacaagatg aagggtatgc agtaggagca
    79801 tttaatgtag aaaatatgga aatggtaatt gctgttatag aagctgctga ggagttaaat
    79861 tctccagtaa tattacaaac tactccatct actgtaaaat atgcaggtct tgattattat
    79921 ctagcaaatg caaaggttgc tgcagaaaga gtaaatatac ctgtagcaat gcatctggac
    79981 catggttcaa gttttgacct tgcaatgaaa gctttaagaa gtggatatac atcaataatg
    80041 atagatggtt ctcatgaaag ctttgaaaat aatatatcta tatctaaatc agtagtaaaa
    80101 gcatgtagtc cttctcttat accagtggaa gcagaacttg ggaaagttgg tggaaaagaa
    80161 gatgatttag atggcgggaa tagtaatgat tatacaaatc caaaagaggc aaaagagttt
    80221 gtcgatagaa caggaatatc ttcattggct attgctatag gtactgcaca tggattgtat
    80281 aagggtgaac ctaaaataga tttagatagg ttatcagaaa ttaaaaatgt agtttcaata
    80341 cctttagtat tgcatggagg ttcaggaata catgatgata ttataaaaga agctataaaa
    80401 agaggtattg caaaagttaa ctatgcaact gaattaagaa ttgcatatag taaaggggtt
    80461 aaaaaagttt tagatgaaga ttctgaggtt atagacccta aaaagtatgg attagcaggg
    80521 cttcaatcag taaaggattt tgtgaaagaa aagattaaag tgtgtgggtc tgtaaataga
    80581 gtataaaaat aaaatatcct aaatttattt tagataagtt taggatattt gttatatgaa
    80641 aaatttatat taattatatg taaatggtgt atttttttca tttaattgat gaaaaatatc
//
LOCUS       DAEOTL010000009        70631 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEOTL010000009 DAEOTL010000000
VERSION     DAEOTL010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70631
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.009"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(382..1374)
                     /locus_tag="KRH82_000868"
     CDS             complement(382..1374)
                     /locus_tag="KRH82_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8654161.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(1383..2441)
                     /locus_tag="KRH82_000869"
     CDS             complement(1383..2441)
                     /locus_tag="KRH82_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBG8654162.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            2566..4029
                     /locus_tag="KRH82_000870"
     CDS             2566..4029
                     /locus_tag="KRH82_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBG8654163.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            4131..4928
                     /locus_tag="KRH82_000871"
     CDS             4131..4928
                     /locus_tag="KRH82_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8654164.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            4941..7043
                     /locus_tag="KRH82_000872"
     CDS             4941..7043
                     /locus_tag="KRH82_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBG8654165.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            7111..7590
                     /gene="rlmH"
                     /locus_tag="KRH82_000873"
     CDS             7111..7590
                     /gene="rlmH"
                     /locus_tag="KRH82_000873"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBG8654166.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            7739..8050
                     /locus_tag="KRH82_000874"
     CDS             7739..8050
                     /locus_tag="KRH82_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654167.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            8098..8364
                     /locus_tag="KRH82_000875"
     CDS             8098..8364
                     /locus_tag="KRH82_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8654168.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNF"
     gene            8628..9329
                     /locus_tag="KRH82_000876"
     CDS             8628..9329
                     /locus_tag="KRH82_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654169.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLFKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNENSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            9553..10854
                     /locus_tag="KRH82_000877"
     CDS             9553..10854
                     /locus_tag="KRH82_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8654170.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            10991..12085
                     /locus_tag="KRH82_000878"
     CDS             10991..12085
                     /locus_tag="KRH82_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBG8654171.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFLKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            12087..13220
                     /locus_tag="KRH82_000879"
     CDS             12087..13220
                     /locus_tag="KRH82_000879"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBG8654172.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            13238..14347
                     /locus_tag="KRH82_000880"
     CDS             13238..14347
                     /locus_tag="KRH82_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBG8654173.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            14397..15152
                     /locus_tag="KRH82_000881"
     CDS             14397..15152
                     /locus_tag="KRH82_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBG8654174.1"
                     /translation="MERINMNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGV
                     LSKNYSTVEVAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFT
                     GVATSRALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMG
                     GSSIKFFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKV
                     IPHVYTSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            15157..16149
                     /locus_tag="KRH82_000882"
     CDS             15157..16149
                     /locus_tag="KRH82_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBG8654175.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(16337..17218)
                     /locus_tag="KRH82_000883"
     CDS             complement(16337..17218)
                     /locus_tag="KRH82_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8654176.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            17492..18880
                     /locus_tag="KRH82_000884"
     CDS             17492..18880
                     /locus_tag="KRH82_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654177.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFTPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            18908..19861
                     /locus_tag="KRH82_000885"
     CDS             18908..19861
                     /locus_tag="KRH82_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBG8654178.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEVIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            19921..20145
                     /locus_tag="KRH82_000886"
     CDS             19921..20145
                     /locus_tag="KRH82_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654179.1"
                     /translation="MNEKPSFKQIEVILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            20138..20650
                     /locus_tag="KRH82_000887"
     CDS             20138..20650
                     /locus_tag="KRH82_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBG8654180.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTVMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            20682..21536
                     /locus_tag="KRH82_000888"
     CDS             20682..21536
                     /locus_tag="KRH82_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBG8654181.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENVESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            22070..22864
                     /locus_tag="KRH82_000889"
     CDS             22070..22864
                     /locus_tag="KRH82_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8654182.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            22968..23792
                     /locus_tag="KRH82_000890"
     CDS             22968..23792
                     /locus_tag="KRH82_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8654183.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPDKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIVAIVLVAINPGNALYKRFSKNTTQIL"
     gene            24423..26510
                     /locus_tag="KRH82_000891"
     CDS             24423..26510
                     /locus_tag="KRH82_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8654184.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPKLEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLIEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            26525..26812
                     /locus_tag="KRH82_000892"
     CDS             26525..26812
                     /locus_tag="KRH82_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654185.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            26839..28110
                     /locus_tag="KRH82_000893"
     CDS             26839..28110
                     /locus_tag="KRH82_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBG8654186.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            28168..28767
                     /locus_tag="KRH82_000894"
     CDS             28168..28767
                     /locus_tag="KRH82_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBG8654187.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            28772..29677
                     /gene="dapA"
                     /locus_tag="KRH82_000895"
     CDS             28772..29677
                     /gene="dapA"
                     /locus_tag="KRH82_000895"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBG8654188.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            29783..30415
                     /locus_tag="KRH82_000896"
     CDS             29783..30415
                     /locus_tag="KRH82_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBG8654189.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNIRKI"
     gene            30893..33400
                     /locus_tag="KRH82_000897"
     CDS             30893..33400
                     /locus_tag="KRH82_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8654190.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            33742..35904
                     /locus_tag="KRH82_000898"
     CDS             33742..35904
                     /locus_tag="KRH82_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBG8654191.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYGDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISNIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIALDKIISNSSFNKIIKGEH"
     gene            35909..36526
                     /locus_tag="KRH82_000899"
     CDS             35909..36526
                     /locus_tag="KRH82_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654192.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            36715..37059
                     /locus_tag="KRH82_000900"
     CDS             36715..37059
                     /locus_tag="KRH82_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBG8654193.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            37629..38495
                     /locus_tag="KRH82_000901"
     CDS             37629..38495
                     /locus_tag="KRH82_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBG8654194.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSSELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            38608..39012
                     /locus_tag="KRH82_000902"
     CDS             38608..39012
                     /locus_tag="KRH82_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBG8654195.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            39179..39628
                     /locus_tag="KRH82_000903"
     CDS             39179..39628
                     /locus_tag="KRH82_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654196.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(39784..40161)
                     /locus_tag="KRH82_000904"
     CDS             complement(39784..40161)
                     /locus_tag="KRH82_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8654197.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            40423..41340
                     /locus_tag="KRH82_000905"
     CDS             40423..41340
                     /locus_tag="KRH82_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBG8654198.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWATCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNVTLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            41824..43242
                     /locus_tag="KRH82_000906"
     CDS             41824..43242
                     /locus_tag="KRH82_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBG8654199.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            43318..44130
                     /locus_tag="KRH82_000907"
     CDS             43318..44130
                     /locus_tag="KRH82_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8654200.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            44553..45170
                     /locus_tag="KRH82_000908"
     CDS             44553..45170
                     /locus_tag="KRH82_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBG8654201.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGVKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(45327..45779)
                     /locus_tag="KRH82_000909"
     CDS             complement(45327..45779)
                     /locus_tag="KRH82_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBG8654202.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            46227..47585
                     /locus_tag="KRH82_000910"
     CDS             46227..47585
                     /locus_tag="KRH82_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8654203.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDGEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRVL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            47858..48238
                     /locus_tag="KRH82_000911"
     CDS             47858..48238
                     /locus_tag="KRH82_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8654204.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            48363..48563
                     /locus_tag="KRH82_000912"
     CDS             48363..48563
                     /locus_tag="KRH82_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654205.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            48759..49487
                     /locus_tag="KRH82_000913"
     CDS             48759..49487
                     /locus_tag="KRH82_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8654206.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            49509..50426
                     /locus_tag="KRH82_000914"
     CDS             49509..50426
                     /locus_tag="KRH82_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBG8654207.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            50568..51752
                     /locus_tag="KRH82_000915"
     CDS             50568..51752
                     /locus_tag="KRH82_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBG8654208.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            51859..52047
                     /locus_tag="KRH82_000916"
     CDS             51859..52047
                     /locus_tag="KRH82_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBG8654209.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            52196..52846
                     /locus_tag="KRH82_000917"
     CDS             52196..52846
                     /locus_tag="KRH82_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBG8654210.1"
                     /translation="MKKNYEIILFDLDGTLTDPKEGITKSIQYSLNSFGIEEDLDNLE
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            52949..53887
                     /locus_tag="KRH82_000918"
     CDS             52949..53887
                     /locus_tag="KRH82_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBG8654211.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            53913..54764
                     /locus_tag="KRH82_000919"
     CDS             53913..54764
                     /locus_tag="KRH82_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8654212.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(55049..55783)
                     /locus_tag="KRH82_000920"
     CDS             complement(55049..55783)
                     /locus_tag="KRH82_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBG8654213.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            55908..56624
                     /locus_tag="KRH82_000921"
     CDS             55908..56624
                     /locus_tag="KRH82_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBG8654214.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDNDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            56758..57450
                     /locus_tag="KRH82_000922"
     CDS             56758..57450
                     /locus_tag="KRH82_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654215.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            57440..58621
                     /locus_tag="KRH82_000923"
     CDS             57440..58621
                     /locus_tag="KRH82_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBG8654216.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSIISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTMFEVQLPIIQS
                     A"
     gene            58903..59358
                     /locus_tag="KRH82_000924"
     CDS             58903..59358
                     /locus_tag="KRH82_000924"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBG8654217.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            59348..60073
                     /locus_tag="KRH82_000925"
     CDS             59348..60073
                     /locus_tag="KRH82_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBG8654218.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            60045..62426
                     /locus_tag="KRH82_000926"
     CDS             60045..62426
                     /locus_tag="KRH82_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBG8654219.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKNRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(62631..63860)
                     /locus_tag="KRH82_000927"
     CDS             complement(62631..63860)
                     /locus_tag="KRH82_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBG8654220.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            64461..65375
                     /locus_tag="KRH82_000928"
     CDS             64461..65375
                     /locus_tag="KRH82_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654221.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            65399..66034
                     /locus_tag="KRH82_000929"
     CDS             65399..66034
                     /locus_tag="KRH82_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBG8654222.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAEGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            66410..67126
                     /gene="pyrF"
                     /locus_tag="KRH82_000930"
     CDS             66410..67126
                     /gene="pyrF"
                     /locus_tag="KRH82_000930"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBG8654223.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVRAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVREIENA"
     gene            67152..68195
                     /gene="carA"
                     /locus_tag="KRH82_000931"
     CDS             67152..68195
                     /gene="carA"
                     /locus_tag="KRH82_000931"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBG8654224.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGIKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            68248..>70631
                     /gene="carB"
                     /locus_tag="KRH82_000932"
     CDS             68248..>70631
                     /gene="carB"
                     /locus_tag="KRH82_000932"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HBG8654225.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQN"
BASE COUNT        27750 a         7545 c        12359 g        22977 t
ORIGIN      
        1 aaagtacata aattcaaatt aatataattt tctatgttac aggatacttt taagtatctt
       61 tttttaattt catttttatt gtattaaaaa tgaaattaaa catacaacaa aattttgaat
      121 tacttgcaat gtgatagttt taaatataaa atttagaatc attctagcat agtattatgt
      181 aatatagcaa atttaattta tagtatcaat aaatatagac tactaagaat gtaaatgatt
      241 tgttagatta agatacatta gatatgtaaa tagaaaaata aaaagtatgt tttaatttat
      301 gtgatataag ttttaaacag agaagcaagt ttgctcttac ctctctattt aaaaataaaa
      361 aaatgttttt taagggctat tttatttaaa tctttcccat ctcaaatcat ctccagtaaa
      421 ttctaaaatc ctaaacttat ctaatattct agagagagtt ctttgagtgt aagtatttcc
      481 tatttgagat ggtgttaagt tggttgaaat aatgattttt ttaccagcaa caagtcttgt
      541 atttacaata ttgaagattt ctccactagt aaaagaatta ttaagttcag ttccaaggtc
      601 atctattatt aataaatcac aatcaaacaa gtttttataa ttatcttcac ttatttgatt
      661 atttgtgtct cttctaaatt tataatcttc aagaatatct aaaattctaa aagaagtttg
      721 atagattaca acattgcctt tatctaacaa ttcctttgca atacaattgc acatataggt
      781 ctttcctagt ccagtagaac cataaaacag tagattttca ctattatcct tcttaaaatc
      841 atgaacaaaa ttttcgcaga tacttaaatt atttagcata ttttctctag gagatatttc
      901 accatcagag cctttcttag gagaaaatat attcaagtta aaattcgaaa aattttcctg
      961 acttaaaatc ctatctaaat tagacatttt ataagcttca tttacaattt cttgtttgag
     1021 gcaagaacat ttttctccat taggtaaaaa tcctttatct ttacaagaaa tacattgaaa
     1081 ctttatttcc aagtaatcaa gaggtatgtt actttcagct aaaagtcttt ctttctttac
     1141 ttttaaagac tctatattct ctttagtctt ctttacaatt tcatctttag atttgggatt
     1201 taaaagtact atcttagcta aactgagacc tattttagaa atttcatcat ctatagattt
     1261 tatctccggg attctattat atacctcatt ttttctatgt tctaataaga gttcattatc
     1321 atctcttctc ttagcatatt tagcaagtat ttttcttatt ttatcctcat tcatttaatc
     1381 acctacttaa acttttcttt ttgacttttt ttaataatct catcgagctc atcagaggta
     1441 tactgagtga atgtttcgtt gaaattatga aacttagttt ttttgtaagt attgttgttt
     1501 tgagtagtat taatctgctt cttattaata ttctccttaa ctatacgttc ttcctctttt
     1561 tgctttaaat catttaaatt ttttatattt ttttcattcc aatttttaat tataccattt
     1621 atataagata tacttgggtt tgaaatattc ttagacttag aacatgcatt tattatcaaa
     1681 tctatatcca tattaaattt atcaaaccag gtgtccataa gttctttttc tgattttgat
     1741 ggttgtcttg aaaatcccaa ttcattgaaa atcgttttat ataaaatata tcgttcactt
     1801 cttaccaaaa agctttcttc aacatctttt ggtgtatata aatttgaatc ataccaattt
     1861 ctaataatgc cttcaatgta tttaacgggc tttgatgtac cagttttatc tttgacgtat
     1921 tcatatgcgc aaagtatcat atcggggctc atattgtatt tattcattat atccataata
     1981 ctcatctttt cacttgggtc gagatatcgc ccaactattt tatttataga attaaacatt
     2041 tttctaatac ttggattttc agaagtagat acaactttat ctgtattaga ttttatagat
     2101 gaattattgc ttaatatatt ctcaatatag aaatttttta aatctaaaaa ttctattgaa
     2161 taattaaaat tatcatattc tccattgtca tgtattttta taatcttctt ttcttcccag
     2221 aatttccaag cagataacac atcagacaat ggtatattta ggtttttggc tattgaatta
     2281 ttgtcgaact taggattaga agtaatatca catgcttgtc tatatcctaa aagataaact
     2341 tttacgtata acccgtccgc cattggcata aatatatcta taaagatatt gggaatagtg
     2401 atttcaccta aatctatttc attgctttct ttaaaaaaca ttttatcacc tcagattaaa
     2461 ttatatcatt ttttatatta tatttgtctg taaacaaata aaaggtcaca agattagcat
     2521 gtaaatattt tctaaaagta ttcattttga aaaggaggag atattttggt tataaaattc
     2581 aaccaaaaag taagaagaac attatcagta gcgattctat ttatggtatt aataataggt
     2641 tgctttatag aaaaggatga cagtttagaa acatacaaag aaaaaactaa ttcaaaaata
     2701 aatcagtata atatggatgt tatatttgat gatgagacta agaggttaat gtgcaatcag
     2761 aatgttgact acataaataa tacaaaatca aacatagata aaatatattt ccatatatat
     2821 ccgaatgctt tttccaagaa agattttgct ccttttgaaa aaagtgaaat gacaagggct
     2881 tatcctaatg gatttaacga aggatatata gatataaaga atatattaaa taataatagt
     2941 aaaatggagt ataaaattaa aggagacaaa aatgacatat tagaaataga attagggaaa
     3001 gagttaaaac caaatgaaag aatgtcatta gatataaaat ataacgtaaa aataccaaat
     3061 tcaattggaa gatttggata tggagaaaat actataaatg ttactaattg gtttcctata
     3121 gcttgtgtaa atgatgaaag gggatggaat ttaaagagtt atgaaactat tggcgaccca
     3181 ttttatagtg agactagcga ttttcatgtg aaactattga ttccaaataa atataaaatt
     3241 gctcatacag gaaaacttat tgatgataaa catgataata agaaaatgct atatgaaata
     3301 gaagctgaaa acgttagaga ttttgcattt atactaagta gcaaatttga tgtaaacaaa
     3361 gtagattcaa agggagtagc tatcaataca tataatttaa ataaaaagct ttctaaaaaa
     3421 gcaactgaag tggcaaaaga ttcaataaat atatttagtg aattatttgg aaagtatcct
     3481 tacaaagaat tttctgttgt agcaagtgac ttttttatag gggggatgga ataccctatg
     3541 cttgttatga tagaccaaag tttatataat gaaaaaaatg aatttttact agaatatgtt
     3601 attgcccatg agacagccca tcaatggtgg tattctgctg ttggaaatga tgaaataagt
     3661 gaaccctggt tagatgaagc acttactgaa tattctacaa tagtttattt tgaacaaaag
     3721 tatggtaaag atatggcaaa caagcttata aaaactatgg agatacagac aaaaagttat
     3781 ttgagcgaaa atatatttaa gccagcaaat gagtataaaa attctactga atacagcttg
     3841 aatgtttata caaaaggcgc aatagcattt aatgaaataa gaaaagaagt tggagataaa
     3901 gtattctttg agactttaaa tgagtactat aataaatata agcataaaaa tgctaatgga
     3961 agagcttttg tggaactatg gaatagtaaa ggtgtagata taaataagat tataagtgaa
     4021 tgtaagtaaa cagtgaatgt aagtaaattt tgtgcagagt attaaatttt atttaatact
     4081 ctgttttttt ggtataatat aatttataag gcagaaaaag aggtgaagga atgctaaagt
     4141 attgttcagt agggagtggt agtagtggta attgccacta tatagggtat aaaaatacta
     4201 atatactagt agatgcagga ttaagtggca agagaataac tacaggtctt aaagacattg
     4261 gtgtagatgc agataaatta aaaggaatat ttataacaca tgagcatgtt gaccatataa
     4321 aaggagcagg tatattatca agaaagtttg atataccagt atttgctaat ataaaaacat
     4381 ggtgttctat gaaggacaaa ttaggtgaca tcaaagataa aaatatgaaa gtatttgaaa
     4441 atgataaaac ctactcatta ggtgatatca tagtaagacc tttttcaata gaacatgatg
     4501 cgtctgaccc agttggatat aatttttata cagagagtga tgaaaaaatg tctatagcta
     4561 ctgatatagg atgtataact caaaatataa aaaaacatct atataaatct aaattagtag
     4621 tattggaatc aaattatgac cctaatatgc ttatgatggg ttcatataca tatgctttaa
     4681 agaaaagagt aatgtcaagt actggtcatt tatccaatga agatgcagct aatttctgcg
     4741 ttgaacttat taatgaaggt acagaatcta tattattagc acatttaagt aaagaaaata
     4801 attttcctga gttagcgtat gagacttcaa aaggagtatt agcatcaaat gatatagtag
     4861 ttggacaaga tgtaaaacta gatgtactat cacgaaatga tgtttctaat gtttatgaga
     4921 tgaagtagag gtgaataact ttgctaaaga gaaattttga aaatgttgag gataataaaa
     4981 ttttatactc tataaagcag ggtatgattt tagcgatacc tgctattatg actggttcaa
     5041 ctgctcttgt aattttgaat cttccaataa aggcttatca agaatattta tcaggcttgt
     5101 ttaatggaga ggttacaaat attcttaact ttataaatga ttctacttta ggaattattt
     5161 cattaataat attattaaca ataagctata gttatggaaa aatatatggg agcaagtata
     5221 cagtacttgt tcctatagtt gcaatgtgct cttttttagt attttcacat ggtaatgagc
     5281 ttaattctta tatagaaata tttaaaacaa agtggttatt tacatctata attgtttcta
     5341 tgacatcttc tgtattgttt gtaaaactta cagaatcttt tgttacaagt gtaaagtttc
     5401 atacagaagg ggctgatgca gactttaata tggtagtttc ggctatagtt cctttcataa
     5461 tagtagtatt tttgttttct atttttagag tgataatgat aagtctaatt ggcagttcaa
     5521 actttcaaga tatattttat aatttatttt caaatgtttt taataaaatg ggaacaaacc
     5581 ttatgagtgc tctgttgttt atttttttaa tgcactttat gtggtttttt gggattcatg
     5641 gtagtaatgt attagatacc gtcgcaaaaa atttatttga aaatagtatg gcaattaaca
     5701 taaatttagt taataataat caattaccaa cagaaatttt tactaagacc ttttttgata
     5761 caatggtttt attgggagga tgtggctctt tactatgttt agtaattgca atttttctta
     5821 gtgaaaaacg tataaatgta agaaagttag ctaaaattgc ttcaatacca gctcttttta
     5881 atatcaatga gatgctagtt ttcgggatac caattgtttt taactatatt atgtttgtac
     5941 cttttgtaat tactcctata atcttaacca ttacaagtta tgtggctatg tctacaggta
     6001 ttgtaccatg tacagtttca gctgtagaat ggacctcacc tatattttta agtggatata
     6061 tgtctacagg ttcaataaga ggtagtttgt tgcaagtatt taatttatgt gttggtgtta
     6121 tgatttatat tccgtttata aaaatgtcgc aaaatagata tacatatatg tttaaaaata
     6181 atatagaaaa tttaacaaac ttattaaaaa ggtatgaatt aacaggtgaa cagcctaatc
     6241 ttctaaacca taatggtaaa ataggttcaa tttcaaaaat gttggcatca gacttgaagt
     6301 ttgctatgaa aagaggagaa atagagcttt tttatcaacc acaagtcaat tataatggaa
     6361 atgttgtggg agcagaggga ttacttagat ggaaacattc aataggaggg ttcatttatc
     6421 caccactagt tataattttg gctaaagaag aagggttctt agatgagctt ggagagtata
     6481 ttattaataa agcatgtatt gatttaaaga agagtgaaaa gctattgaga aatcctgtta
     6541 agttctctgt aaatatatct ccagaccaac ttgatgaccc taagttacca gagcaaataa
     6601 aaaatatcat tagtagtaat gatataaatc ctaatatgtt aggtatagaa ataacagagc
     6661 aaattgcatt atcaggttca caaataatta ttgaacgtat caatgcgata cataacttgg
     6721 gaataaagtt aattatggat gattttggga tggggcatag ctctcttata tatcttcaaa
     6781 ataataactt tgatatagtt aaattggatg gttcattagt taaagagata cttacaaata
     6841 aaagaagtag tgaaattata atgactattg taaatctttc aaaaaattta gattttgata
     6901 tagttgttga gtatgttgaa aatatagacc aaagggataa gttatatggt ttaggatgtg
     6961 aaatatatca aggatattat tatagcaaag caataccttt tgaagagttt gtagaatatg
     7021 caaatcaaga aagagagata taattttata agagcttgta aattctagta atgcatagat
     7081 ttgtaataaa attaagttta ggagaaatat atgaatataa gtatagtagt agtaggtaaa
     7141 attaaagaaa aatatttaaa attaggtatt gatgagttca agaaaaggct ttctaagtat
     7201 tgtaagttag aaattataga gttggatgat gaaaaagctc cagagaattt gagtgttaag
     7261 gaaatggaaa ttataaaaga caaagaagga aagaaaattt tagggaagat aaagcataat
     7321 agttatgtta tagccttggc tattgatggg aagggtttat cctctgaaga acttgctaag
     7381 actatgagtg atttagcagt tagaggtaat agtagtctct gttttataat aggaggttct
     7441 ctagggcttt ctgatgaggt tttaggaagg gctgattata ggttatcttt ttctaggatg
     7501 acttttcctc atcagatgat gagattgata ttgttagaac agatttatag ggcttatagg
     7561 ataaataatg gagaaccgta tcataaataa atgatacggt ttttgttagt ttgcaactta
     7621 ataatattaa aataacaaaa aagtattgaa agtatattgc atttaaggta gaattaaata
     7681 aaatattata acattataat gtttatatgg ttgttaataa aaatttggag gaaaatatat
     7741 gataaaaata atgttggcct gttcagcagg aatgtctaca agtttattag ttactaaaat
     7801 ggaaagtgca gctaaagaaa atggtataga gtcgcaaatt tgggcaatac cagaatcaac
     7861 tatacaaaat gaaatagaaa aatgtgatgt attattacta ggaccacaag ttagatatgt
     7921 attacctaag gctcaagaaa ttgctaagcc atataatata ccagtagaag ttataaatat
     7981 gatgcactat ggaacagtta atggagaagc tgttttaaat agagcgatag aacttaacaa
     8041 cactaagtaa tataaattat aatgtatttt taatatataa attgggagaa tcaaaggatg
     8101 gatgaaaaga ttatagaaat atcttttaat ataataggtt atgcaggtga aggtaaagga
     8161 ttagcttttg aagcaataaa agaggctaag aatggaaata tagaaaaagc aaaagaatta
     8221 ttaaaagagt ctagggaagt tataaataaa gcacatagat atcaaacaga attaatacaa
     8281 aacgaagcta gtggaaacag gactgaaata agtgtcatac ttatacatgc acaggaccac
     8341 ctaatgaatg gcatgaattt ttaacagtta gctgaggaaa tcgttgattt acatttgaaa
     8401 ttacaagata aataaaaatt aaagagaata aattaagaga gttcttaaaa gatacattat
     8461 gtgtagcaca ctaattgtta gattattgat tcaatattta gtgagtaata cattaggatt
     8521 attttgagga ctctttttat atttagttta aagttaataa atatttatta ttaataatat
     8581 aagattatat gttataatat tataacatat aatttaagag gtgaatcatg ttaagaaatc
     8641 aaccattata tatacaagtt gtagatatat taaagcaaaa aatattaaat aacgaatata
     8701 aaattgatga aaatattcca acagaaaggg agttagagca agagtttgga gtcagtaaaa
     8761 ttactattag aaaagctatt gagatattag aatcagaagg atatgtagag aaaaaaagtg
     8821 gaaaagggac aaaagtaata agtaatagcc tttttaataa gctatcaaaa gcagagtctt
     8881 tttcaagtat acttttatct aaaggtcata agttatttaa ggagactatt tcaattgaaa
     8941 aaataataaa tgatacaaat tcacaagtat ttagtatatt tggagaaaaa tgtagcaaga
     9001 ttactagaat gtattattta gatagtaagc catatatatt ttttactcat tatattcctt
     9061 ttgatgaaaa tctaactgtt gaaagtttta ataatgaaaa ttctttatat atgtacttat
     9121 ataggagaaa tataaatata actagatttg aagatgaatt ttttatagaa gaatcagaac
     9181 tagaggtatc aaaggcttta aatctagcta aagacatatt attaggaaga aaaagaaaga
     9241 cctatgatga gaatgataat atagttgagc tatcatttgc aagatataat acagaagtac
     9301 aaaactatgt aattaaatac gaaatataat aagaatcctg agtttattga aatgataata
     9361 tgctcaggat ttttgtttag ttgtaaaaat aaaaaatatt ataacattat aatgtttaca
     9421 accaaacatt ataatgttat aatattttta ataaacaagt gatattatca attacataaa
     9481 aattagttta tgttatgaaa tcgttattgc attataaata aaggataata tcaataatac
     9541 agggggataa ctatggaaaa attcgcaagt tttttagagc gcaagattat gcctgtagca
     9601 gcgaagataa gtaatcagag acatatgaga gctgtaagag caggtataat agcaacatta
     9661 ccactaacaa tagtggggtc atttttcaca atattattaa acatacctat tgatgcttat
     9721 atggatttta tagctccatt taaagcaata ttagatatac catttagata tactgtagga
     9781 tttttatctc tatatgctac ttttgggata gcatcatcac ttgctaaaag ctacgattta
     9841 gatacaacag gtgttggtat gcttgcagtt atggcatttt tagtttctac aatagttcca
     9901 actcaagtag ttgaaccagt aggtggagtt atagaagctg gtagatggat ggatatggca
     9961 aaacttaatt cgccatcatt atttggagct atcgtaacat cattaattac agttgaaata
    10021 tatcgtttta tgaaggaaaa gaatattaca attaagatgc cagcaggagt tccagtagag
    10081 gtttcaaatt catttactgc attattaccg acagcagtaa ttttaatgtt attctgggta
    10141 ataagacata ttttaggatt tgatataagt gttgcactaa gcgctatgtt atcaccttta
    10201 aaaggattct tatcaggaaa tagtttaggt ggtgggttac tgacagtatt cctaataact
    10261 ttattctggg tacttggaat acatggtcca gctataatgg ggccagtaat aagacctata
    10321 tgggacatgt ctatagcaga aaatataact gcattcacag aaggagtatc agctcatgca
    10381 atgccaaaca tatttacaga acaattttta cagtggtatg tatggatagg gggagcaggg
    10441 gctactcttg cattagttgt aatgtttatg ttttctaagt cacaatatct aaaaagttta
    10501 ggtagattag gatttttacc agggttattc aacataaatg aacctataat atttggagca
    10561 ccaatagtta tgaatccaat actagggata ccatttataa ttggacctat aataatgaca
    10621 attctatcat atgttcttac tattacaggg gttataccta tgatggtagc aagattacca
    10681 tttgcaatgc cagcaccaat agcagcagta atgagtacta actggagtat actagcaggt
    10741 atcttagtat taatcaactt tgtgatatca tttgctgttt attatccatt cttcaaagtt
    10801 tttgaaaaac aacaattaca aagagaacaa gaagaaatga gtgaaaattt ataaaaatac
    10861 atagatatag aggttttgta ctatataaaa tatagaaaaa acttataagt tattaagggt
    10921 aaaggtagga ggaatgacct ttgcctttaa ttttatatat tttaaataat gtaatttgag
    10981 gaggagaaag atggaaagaa gattaggaat atcagtatat ccagagcata gtaacatgga
    11041 agatgataag gcatatataa aaatggcttc aaaatacgga tttaaaagaa tatttatgtg
    11101 catgctttca attacaagac ctaaggaaga agttaaaaaa cattttaaag aaattataac
    11161 ctatgcaaga gaattaggat ttgaagtaat ccttgatata gctccaaaca tatttgatat
    11221 attacaaata tcttatgatg atttaacatt ctttagtgag ttaaatgcta gtggaataag
    11281 gcttgactat ggatatgatg gaagtaaaga agctatgatt tctttcaatc catatgattt
    11341 aaaagtggaa ctaaatatga gtaatgatgt agcatacttg gataatataa ttacttacaa
    11401 gccaaatgta aataatatat atggttgtca caatttttat cctcaaaggg gtacaggctt
    11461 gccatatgat ttttttgtaa gatgttcaaa tagatttaaa aagtatggaa taagaactgc
    11521 tgcttttgtt aattcaaaat atgcaacaat cggaccttgg aatataaatg atggattgtg
    11581 tacgcttgaa atgcatagaa acttagatat tgctacagca actaagcact tattcgcaac
    11641 aggattgatt gatgatgtaa ttgtagggaa tgcatatgca agtgaagatg aattaaaaag
    11701 aatgtctgaa gtaaataaat atcaagttgt atttaatgta gtaactgagg aaaaaacttc
    11761 tgaagtagaa aagacaataa tggcaaatga gcaacacttt agaagagggg atataaccaa
    11821 ccaagtagca aggtctacag aagtaagaaa aaaatatgct aaagaaaatt tccttaagca
    11881 tgataatacg accatcttta aaagaggaga tgtagtgatt ggtaatgatg actttggaaa
    11941 gtataaaggg gaattacagt tgatacttca agattgtgca gatgaaagaa aaaataaggt
    12001 aggtagaata aaggaagacg aaataatgct tttagacttt attgaacctt ggagtaaatt
    12061 taaacttatt ttagagggag agtaaagtga agatagacat attaataaaa ggtggaaaaa
    12121 cagtagataa aagtataatt gatatagcta tattagacga taaaataata gaagtaaaaa
    12181 atcagataga tgattctaag tatcaggcaa atcaaattat aaacctagat ggagaaaaat
    12241 ttattagtgc tggttggata gatatacata cgcactgcta cgaaagacta gacctttata
    12301 aggattatcc agatgaggtt ggaataaaaa gcggtgttac tactgtagta gatgcaggaa
    12361 caacaggagc tttagatata ggtaaatttt atgaagatac taaaaaatat aaaacaaatg
    12421 tatatgcttt aataaatatt gctaagcagg gaataacatc tcaagatgaa ctttcaagta
    12481 tgatgaatat tgatgaatat gaacttaaaa gagcagttaa aaaatacaaa gattttgttg
    12541 ttggaatcaa agctagaatg agtaaaagtg ttgtaatttc aaatgatgtt gaacctttaa
    12601 aagtagctaa aagaataaaa aatgaactta atctacctat gatggttcac tttgggagtt
    12661 ctcctccaac gatagaggat atatttgact atatggaaaa aggagatata ttaacccata
    12721 tatataatgg aaagccaaat ggaatactta gaggcaatga ggttaaaaaa gaaatcatag
    12781 aagctagaga aagaggtata atccttgatg taggtcatgg aaccgaaagt tttagtatgg
    12841 atattgcaat gaaatctaag gatgcaggaa tttttccaga cactataagt acagatatat
    12901 atattaaaaa tagaataaat ggtccagtgt ataatctatc tacaacaatg gaaaagttta
    12961 tatatatggg ctattcactt gaagatataa tagataaagt tactaaaaat gcagcagatg
    13021 caataagttt aaaaaataaa ggtttaataa aagaaggata tgatgctgat ttaactatat
    13081 ttgatgtggt taatgaagaa aaagaacttc aagattcttt gaataagtca gtaatcacaa
    13141 gtacgtctat aaagccaaga gcagtagtag tcaatggaga atatttaaat ataggtaagt
    13201 ctataggaga gaatgagtag aagggagaaa ctattgtatg agtagtatat ttgaaaaata
    13261 ctctgtaaga cgtgttataa atgcttcagg caaaatgact atactaggag tatcaacagt
    13321 agataaggaa gttattgaag caataggtga agggtgtaaa aatttcttta taatagaaga
    13381 acttataaat aaaacaggtg aatatatagc aaatttatta gggtgtgaaa gtgcactaat
    13441 agtttctagt gcatctgctg ggattgcaca gagtgtggga gcaatgatag caaaagatga
    13501 tatgagtcta gtttacaatg taaataatcc taagaaacaa gttaaaaggg aaataataat
    13561 tccaaaggga cataatgttg attatggagt tccagtagaa gtaatgataa gacttggagg
    13621 aggagaagtt gttgaggccg gttatgctaa tatgtgtaac aaggaacata taataagaga
    13681 gataaatgaa aatacagcag caattatgta tattaaatct catcattgtg ttcaaaagag
    13741 tatgctaagt gtattagatg cagtacaagt tgctaaagaa tataatttac ctttgatagt
    13801 agatgcagca gcagaagaag atttaaatgt atattatgaa ttgggagcag acctagtgat
    13861 atacagtggt gctaaggcta tagagggtcc tagctcaggg ttagtaatag gtaagaaaaa
    13921 atacatagat aatgtaaagc ttcaatcaaa gggtatagga agagctatga aaataggaaa
    13981 agaaaatatt gtaggtctaa catgtgcaat tgagagatat ataagtaatg ataaagtaac
    14041 tttaaaagaa atggaggaca agctaaatcc atttatagac aagataaata ctataaaggg
    14101 agtgagtgct agtataacta gggattcagc aggtagagaa atacttcgtg gagaaattga
    14161 ctttaatgaa gatataataa ataagtcaac acaacaaatt ataaatgaac ttagaagtgg
    14221 agagatagct atatacacta gagactataa ggctaatgaa ggcaagattg agattgatat
    14281 aagaagtgta actggaagtg atttagatac tatttataat aggataaaaa atatagtaga
    14341 aagttagagt gtagagtaag tgacattata atgatttaat aaattaaatt ttaccaatgg
    14401 agaggataaa tatgaattgt ataccacaat attataaaaa tagagtttgt ttaaatgttc
    14461 ttgcaggaag cataaaaaat gctaaagaag tatatgatgc ttgtgacggg catgtattga
    14521 taggagtact atcaaagaat tacagcactg tagaagtagc tattgaagat atgaaaaaat
    14581 actcaaagga aatagataat gcaatatctg tggggcttgg agctggagac ccaaatcagt
    14641 caaatatggt atctcagatt tctaaagaac ttcagccaca acatataaat caagtgttta
    14701 caggtgtggc tacgtctaga gcattgcttg gtcaaaatga tagtataata aatggattag
    14761 tttctccaac tggtaaacca ggatttgtaa aaatatccac aggtccatta agttcaaaag
    14821 aaaaagatgg tatagttcct atagaaacag caatagctat gatgaaagat atgggaggaa
    14881 gctcaattaa gttttttcca atgggagggc ttaaaacaaa ggatgaatat atagaagttg
    14941 caaaagcttg tgcaaagcat aatttttatt tagaaccaac aggaggtata gacttagata
    15001 acttcaaaga gatagttcaa attgcacttg atgctggtgt agaaaaagtt atacctcatg
    15061 tttatacatc aataattgat aaagaaacag gtgaaacgaa agtggaagat ataggagtac
    15121 tttataaaat aatgaaagaa ttattgggat agatttatga atatattagc ttttggtgaa
    15181 ataatgatga gactttcagt acctgactac aagttcttaa cacaaaccaa tgaactaaat
    15241 tatataatta caggcacggg attaaatata ttatctggac ttaaaaactt tggatacaat
    15301 acctatatgt tgacaaagtt gcctaataat aatgtaggta aagcatcaag tgcaaatata
    15361 agaaagcttg gagtaaaaga tgactttatc acgtatggag ggaatcatat aggagtgtat
    15421 tttcttgaaa atgggtatgg agaaagacct tctgaagtga cttatttgaa taggttaaat
    15481 agttcatttt gtgagagtaa attacaagat tatgatattg ataaatgttt agaagaaatg
    15541 gatatagtcc atatttgtgg tattgctatg caacttacag attcagttaa agagattgct
    15601 ttagaactag ctagaaaatc ttatgaaaag gggataaaag tattctttga ttttaatttt
    15661 agacaatcat taaatccaga aaggacttat gatgatttag taaatgatta taagaaaata
    15721 ctaccatatt gtcatgggct atttgctagt tatagagata taaataagat acttaatata
    15781 gatagtctaa atataaaatc tagttcagaa ttgattaaaa aagagtatga tatagatatt
    15841 gtagctggaa ctatgagaag atttgatgat atgaataata gatttataaa gggatatata
    15901 tcaaatgatg atggttattt tgaaagtagg gagtataagt tagaaatata tgacagagtt
    15961 ggtgctgggg atggatatgt ggcaggaatt atatattcat atttggaaaa tatgaagagt
    16021 gaagatatag ttgagtttgg ggttgctagt tcggtgttag ctcatacaac ttatggggat
    16081 aattctttag taagcacagg tcatgtactt agactgatga acaatgaaaa aatagatata
    16141 ttgagataat acatttgtat ataataaaat ttttatcttt tttagacaca tttttgactt
    16201 gcttatattt gttaaacaga gttattttta acgattataa atattaaatt agaagttaaa
    16261 taataaaata gtagaaaata gcattaacta tagaaaaaat ggttaatgct atttttatcg
    16321 ttaatattga ttaattttat attatagaaa tgaacttttc taatgctgga tttgtatttt
    16381 ttttattcca tacaactaca acttcaattc tattttctac ttcttttata ggtactattg
    16441 caatatcacg ttctatcatt gtatctgtaa cacaaaatga aggtaaaatg gatattccca
    16501 tgttagaaga taccaatgat tcaatagtat taagattatt tgaacgttgt accacattag
    16561 gtacaaaccc tgcttcacga tatctattct gtatcataga tttttgtcca tactcatccc
    16621 ctgtttcctt tacaaaaata aatttatcat gttgtaattc aattaaatcg atagaatcct
    16681 cattgtaaag tggatgacca ggaggtaaaa gagctaccaa agaatatctt tctacagttt
    16741 tatattcaaa atcttttaat ggttgatttt ctggattaat aacaaaagcg aggtccatag
    16801 aattattttt tactaagttt aaaagttcgg ttatttcatt agtacaaata tccatagata
    16861 tattagggta tgtattagaa aattctttta aatattgttg aagtttgttt ttttcatatc
    16921 ctattaaggt tccaatgctc aaagttccaa aaaaaccatg tgcaaattgt tgtgtttttg
    16981 caatagcatc attgatattt tttattatag tacgtgcctc agataaaaaa acttttccag
    17041 ctggtgttag ttcaacatga cgtttacttc ttgtaaatag agttacattt atttgttctt
    17101 ctaaagcttt tatttgctgt gtaacagcag tttgagaaat ataaaatttt tctgctgttt
    17161 tggtaaaact tagattttct gctacagata taaaatattc taattgttta gtattcaaat
    17221 aatcacccct atttaaactt gattgtttgt aaaccttatt tatctataat taaagcttat
    17281 tatagtataa gaaaatttac ttttaaagaa tattagaaaa tatttgtata aaaatatatg
    17341 ttttaagtat atctttacat tagattttat aaatttatta ataagaataa cttatatatt
    17401 ccaatgaaaa cgatattgga tttaagtaag tttgtctcat aaaatgaaag tatatcaatt
    17461 gataatactt taaaataaga agggagaaaa aatggaagat aaattttatg caaaaggcaa
    17521 cggaaataac ggatatatta aaaatcttga agtttgttcc tttaataact tagatggaac
    17581 ttgtggaatg tttcaaatgg ctctgtacaa aagagatgaa aaatactatt tatatggatg
    17641 ctgttttgga ggaaataaaa aaaatggagt aatgattagc gatattacag acccttataa
    17701 tccacaattt ataaaacatt ttcaaatgtt agaccctaaa gagtatccta caacaacaac
    17761 tcccaaaatt caaatagcag atgatttaat gatagtagca atgagttgtg gaagtggacc
    17821 aggagcactt gttgaccaag ctaaattagc aaatattaag tgtgaagcag gaattagaat
    17881 atacagttta aaagaagacc ctttaaatcc taagttttta ggatattggg attgtggctt
    17941 aaagcatgta atgggtgttc atagattcat gtacaatggt ggaagatatg tacatttatc
    18001 aagtgattgt gttggctttg aaggtctgat ttatagggtc atagatataa taaatcctac
    18061 taatccagtg gaaataggta aatggtggag accagaccaa tatgcagatg gatatccaaa
    18121 tagaactttt gatgcaggag cacctcattg cccagaattt atggataaag gatggcttca
    18181 tggacctcca tttgtaagag acggaaaagc atattgtggt tatggaggag ctggtttagt
    18241 tgtattagat gttgaagatt taacaagacc aagatgctta ggtgaattgc catttacgcc
    18301 tgcattttct agtagacttg caggtgcaag aactcataca gcattaccat tgccaggaag
    18361 agatttagtc gttgttcaaa atgagggaga aagattccag ttctttaaac cagataacat
    18421 tacagatgtt caagctatga ataatataca tatggttgat gttagtgacc caacaaaacc
    18481 aacattaatt gctcaatttc catatcctga agttccaaaa gatttccctt atcctaactt
    18541 taatgttgca ggattaggaa aaccagggcc atttggtcca cataatcttc atgaaccaat
    18601 ggataataag ccatggttag agcaaagagg agatagagta tattgctgtt atttccatgc
    18661 agggctaagg gtttatgatg tatcagaccc atattatatc aaagagctag catattttat
    18721 accaccaaat ccaaataaaa caccagaaga atcttatttc ccaggattcc caggaccacg
    18781 cttggcagta acagaagatc ttatcgttga tgatagaggc tacatcatca tagatgcttt
    18841 agatgatgga ttctatatat taaaaatgaa agaagattaa ataaatacta aagagggaga
    18901 gttgaaaatg aaaatactag gtatttcttt tggaacaaaa aatggaaata atgacacaat
    18961 gtgtaaagtt gcacttaaag gtgccaaaga agcaggggct gaagtagaat ttattcaaat
    19021 gtcatctatt aacattaaac attgtactgg atgttgtgcg tgtgttaaaa ctttattatc
    19081 tgggaaaggt agtatgtgtg tattaaaaga tgattttgaa tggttgcttg acaaaatgaa
    19141 agatgcagat ggtatagtag tttcagaccc tatttttgaa gaaggggcat caggattatt
    19201 ccatactata atggaccgtt ttggacccag agcagataga ggaaataaca ttataggaac
    19261 aaaagttgca gaagttatag gaggaaaaat tccagattca agaatgctta atgataaagt
    19321 aatatcattt atgggaatag gaggttctga ctggggtaca agagttcaat gtgaacatgc
    19381 tatgctagct ctcataccaa tgtggaaagt tatagataat gcttggttcc catgggcaaa
    19441 ggaattagta atggatgata caaggcttgt tcaagttcat caaattggtt taaatatagt
    19501 tgaagcagca aaagattttg aaaaagcttc atatcaagga gaagaaggtg tatgtccaca
    19561 ttgccacaat agattattct accttgagcc aggtactaaa aaggcaattt gtgctctatg
    19621 tggtatagtt ggagagttag atactataag tggaaaaact atatttagtt ttccagaaga
    19681 gcaattaggt catgctcatg atactttacc aggtaagttt atacatggtg atgatattaa
    19741 gaaaatggaa ggtcattatg cagaagttcg taaaacacaa gaatttaaag aaagaaaaac
    19801 atcttataat tttatagagc cattaactaa agaaaagcaa gctggagttt cattaggata
    19861 ataattaaaa tactaagact cttttttaag ggatgttaga tgttatagga ggcttattgt
    19921 atgaatgaaa agccaagttt taaacaaatt gaagttattt tagcagttat ttttttggta
    19981 cttacatatt acaaggttag attaactcca gcatttattg ttatatttat accactatat
    20041 ttaagttatt ttgcagtatc tatgattgta aatcaaatag caattaagct attggagata
    20101 aggcaagcta gggaagctac taattacaat ataggaaatg gatagaaaga aaaaagaaat
    20161 attaacactg tctatgggga ttgctttact acctccttta tgggcagtat tagcacctta
    20221 tataggaata aaaactggag ctgtagcact aatctgtgca ggattatatg taactaatgg
    20281 taataaacaa aaagatggat taaaaataat gtttggtttt tggtgtggag atttatgggc
    20341 agtgttagcc attttaatta tgggatatat gaatttcaat caaaacctag aattattttt
    20401 aacacttagc atattaggtt tttttgcagt tgtaattgca tccttatttg aaaaaataat
    20461 tttcctacca tcatggcttt gtggttgggc tataggtcta actgttatga caggtgaaaa
    20521 tattattaat ttacaagata tttgtattca aattgctgta gctatggcag taggagtatg
    20581 gtacgtgggt gcaggtgtag atttgtttac aatatatatt ttgagtaaag ataggaaaaa
    20641 gggaaattga aagcatgtga atatactttg attataggag aatggctatg ggttttgaat
    20701 ttaaaataat gagaagttta atatatgtag gacttgccaa ggaagaatat agacctaagc
    20761 taatggactg gttatatcgt caccatattc cagatagtat tagcactttt ggaccatatt
    20821 gtactaaata tgccttttat caagcatatc ctacaccaaa tgaaggtgag cgttttggtg
    20881 cacgtaagat gcaactaaca gaacattatt ggcttgtaga tgaacatatg cctgagatgg
    20941 caaatagaat tatgacagaa tatatgccta tggatgttct acgttggcaa gggtgtatac
    21001 cagatgtaga aaataaaagg gttcatgaaa atgtagaaag tggagatgca ggacgtgcag
    21061 taggtggaga taatggatgt ccaccattta tatttgcctt tgttccaata aactgggaag
    21121 aagactttag aggaaaagga cgtactgtac aagatggacc aaactatcgt tggcaattta
    21181 tgattaagta tccagatggt atctctaaag aagaaggaga aaaatggttc tatgatgagg
    21241 tagtgccata ctttacaaac tgttgctatg ttaatcgttt tgtcagtagt aaaataatga
    21301 ttaattatgg agcaactgct tttgaccgtg tatcagaact atggtttgaa ggggaagaag
    21361 aatggtataa agctgtggtt gaagagacaa agtcgtttat taaaaaacca gaatgggcac
    21421 aagaagagga gttcccatat ttaaaaccac aattcaatat cgcatcagta ttcttaggtg
    21481 atatagcaac tatggatgca tactcacagt atcgtggata tataccaatg agataaaaat
    21541 tatagtttgt gataagtaga ggaggcattt actcttactg gtagaagaag acttattgta
    21601 tccttaaaag taggtgaata tatagtttta tatttaaatt tatataaaac taagactaat
    21661 aaatatgaaa caatagaatt agaataattt gataatattt gttaaaagag catttagaat
    21721 gtgtttaaag attaagatat tccttttatg gtagcagata gttgaaataa taaaactgtt
    21781 atcatgaaag gaatattttt atgtatagga aatttttaaa aataaaagtt aaatatgttt
    21841 aagaacatct taaagtgaaa gaatcattgt tagaaatatg tagacaatat agtctttata
    21901 acgtatcata ttaacaagtt tacacttgga ttatgaaata aaaagagtaa ttccaaaggt
    21961 tgtaaatact atgctgactt tgatacttca aagtttaggt gattttgtaa ttgttaatag
    22021 aaatacgttt aatgagcata aagaatttat ctaataatag gagaatataa tgtatacaat
    22081 tggacaagta tctaaatttt taggaatatc tagagataca ctaaaatttt atgaggacaa
    22141 aggattagta aatcctaaga aaaatgatga aaatggatat agaatatata atcaggttga
    22201 tatctatgat attgcaacaa taaactttta tagagaaatt gatatagaaa ttaaaaagat
    22261 tcaagaaata agaaaaagta agagtataaa caatttagaa ctcttactag aagagaagga
    22321 acaaatcata ctaaaagaga tagaatataa aaagcttctc ttaaaaaagg ttcagttagt
    22381 caaagaagat tgtgacaaaa taaaaacata ttttggaaaa tacacaataa aagaaatgaa
    22441 gcctttggaa gtaaaaggta aaataaaaca tgttactaac tatgaggaat atgaagccct
    22501 aaaagagaat acaaacaact taaaaaaagc agttacatta actgatttaa gaagagtaat
    22561 aaattttaat gaagaaggta taatagaaga aaaatttata attgtaaggg aagtagatga
    22621 ctacaacaaa atcatagaag gtgaagttct atctcatccc aattgtattt atactattat
    22681 tgaagatggc agatggtcaa ctggaggaga aaatattgat aataaagtgg aagacagatt
    22741 aagagaaata gcaatagaaa atgaatgtga attacttgga atagtctatg ttaatatatt
    22801 gcttactact tatgaagaag ggattgagcg tatattttta gagatttatg cacctataaa
    22861 ataatataaa agcattgacc tgggacttac tcataggttt aaactcatga tataagcagt
    22921 tataacttat atagcaatta aatattaatt tgaaatgagg attacttatg agaacagaga
    22981 aatcattaaa aaggcctata gccagtttta ttattctaac aaatataatt tttttaccac
    23041 tttttttatt ggtagtagtg actataatgt taaaacttcc aacagtgata tctgacattg
    23101 cgttgtgtat atcagcgtgg tcatccactt ttgcatttat gatattattt aaaaaaattt
    23161 atccagataa gaaattttta gtacacgtaa aagatagatt tagaaataaa cttaaatttt
    23221 caacagtatc tataataatt agtatacaag tcctaatagc tgtagtagtt atatttatat
    23281 tagcatctaa aaatcatgga ataatgccta actttacagt ttcatcatgg ggagcattta
    23341 tatatttatt tttaaaaaat ttatttgcag gatcattagg tgaggaatta ggttggagag
    23401 gatttgttca aaatcatctt cagaaaagac attctccttt aaaagcatcc ataatagtag
    23461 gtttttggtg ggggatgtgg catttaccaa tatggtttac aacaggattc aaaggacttg
    23521 atttaataaa atatattata ttttttatga ttgcaattat atcaatcagt attataatga
    23581 caacttttta taatctaaat aaaactttga taatacctat tgtaatacat caactattta
    23641 attttttaat agggataatt aatggagatt taatagagct tataaattac tatgcaatgt
    23701 tatatttaat agttgcaatt gtattggtag ctataaatcc aggaaatgcc ttatataaaa
    23761 gattttctaa aaacacaaca caaatacttt aataatataa gtgagaatca tatcacaaat
    23821 gagagaaata attctcctta ttaattaatt ttaattaata aatattacaa tagatttatc
    23881 tggaatggaa ggtatgcaga gtgtatttca ttagatgaaa cacttaaaag aatgaaatag
    23941 ataagtatca acttattata tgagagaaac tttaactttc ttggtttaaa atattaaaat
    24001 tataaggaac atttattatt aaatacttta tttatatgaa ttaattgaag aaaaaggata
    24061 ttaaactaca agttaaaaaa taaatttaat atattagaat tataaataag gcacattaat
    24121 tttattttaa attaatgtgc cttttattta tggtaattta tgcataatta gtatcgtttt
    24181 gattctttaa ataaattttt cttggtttct tcacataagg aacttttttt aatttataaa
    24241 atctacagtt atattatagt atctatttta gagaagttta atttttgtat caatctaaaa
    24301 caaaagttat acttaaatga aattgaaaac gataaaattc tcaaataaaa taagtattgt
    24361 ggaggtgatg aaagaatcca atgataatat gaagactaat cttaataaga aagtaggggt
    24421 taatggtagt ggacaaagaa attgtatcaa ttctccagat tttattaaat agcacattga
    24481 ttacaactaa tggattacaa gaggagtcta attcatcaaa gagacaaatt acttatagaa
    24541 taaataaaat caatgacatg cttaaagtaa aaaatgtacc acttatatgt ttaagagctg
    24601 ataaagatat tatcgttaga aaagaaacaa aaaaagcaat taaagaaatt ttagaaaaaa
    24661 actattctaa gaatacttat tattttagta agacagaaag acttttatat atgtatttaa
    24721 tgctttttat taacatggag gatatttcaa ttaatcattt tataaattct ataaaagtaa
    24781 gtaggtctac tgtaaatctt gatttcaagg atttgatacc aaagcttgaa aagaagaaca
    24841 ttaaagttaa gaacaatcgt ataaatggat attacatagt tggcaatgag atggaaatta
    24901 ggagagtgct tattaaaaat attatagaaa ctttgtctaa tgagaaaagt tcaagggtat
    24961 ttgatatttt tattaaagaa tataatttag atagttttga agaggctaaa aaaattatat
    25021 taaagctaat aaaaaaatat gaaattactt ttgttgaaga tagattaata gaatttatat
    25081 atatatttat ctttctaaag gcaaggatgt attcaactag aatagttact caggaaaatg
    25141 tagatattcc taatatttca gttatgagtt caatgaagga gtataaattt gctaaggaat
    25201 tattagaagt atatgggagt gaagataaaa taaagcctca caatataatg tatattagtg
    25261 cttggatttt aggtatatca gtaggaaatt atgaagaaga tacagaagat aaggatgtaa
    25321 tttcaaaaat tgtaaataaa atgatgacaa agtttggata tttaagtgga gtttactata
    25381 taagccaaga aaaaatattt aaacaattat attctcattt tagacctgcc tactatagac
    25441 ttttatttaa attacctatc tataatccga tttgtgaaaa agtaaaagaa gaatataaat
    25501 tagtttatag aattgtaagt aatgcaatga aagagttttg cggattattt ggagaagaaa
    25561 ttcaggaaga agagttagca tatcttacaa tgcactttgc aacacttttt tcaaataaaa
    25621 aagaatttga tggttttaga aaaagaatag cattaatagt ttgttcaaat ggcgttggta
    25681 gttcagctat tttacatgca gaacttacaa acttatttcc tgacttacac tttataccaa
    25741 tgtcggaatc agttggatta gaaaatataa gtgaacctgt agatattgta tttactacta
    25801 attataacgc agagggttta aaaacagatg taccagtaat taaagtaagc cctgttatga
    25861 ccacaaaaga aaaatataag attacacgtg aagtgtatat tcaattaggt gatatttttt
    25921 taagacaacc taaaatagat gaggttatgg atataataaa aaaatatgca aatgtaacct
    25981 ctgaaagtat tctttcaagt gagctattag cttattttac acagatagag aattttacat
    26041 ctaaggaagg agaggggcct atgctaagtg agattactaa tgaaacacta gtaaaaataa
    26101 aggtaaaagc taagaattgg gaggaagcta ttagacagtc agcttctgta ttagttgaaa
    26161 ataacaaagt aactgaaggg tatgtagatg ctatgattaa ctcagcaaaa gcatctggac
    26221 catacatagt aattacaaaa catgttgcac ttccacatgc tagaccagaa gctgggtcaa
    26281 aagagattgc aataggcatt gctactttag atagtcctat tgagtttggg aataacgaaa
    26341 acgaccctgt aaaatatgta ttttgtctaa gtgcaataga caataatagc catttacgtg
    26401 ctatgtctga gctagttgaa ctattggaag aagatgagtt ttttaaggtt ttagatagtg
    26461 ctaaagaagc taaagaaatt attgatttta taaaaacaca cgaattataa aggaggattt
    26521 aattatgtat aaaattttaa tcgcatgtag agcaggagtt ggctcaagtt taatgttaaa
    26581 aataaagact caacaaatta ttaaggaaaa taactttcca attgaagtag agcatggttc
    26641 attggattca ctaaatggat tcaatggaga tgctgtagaa acattaattg atgttgctga
    26701 agaattaaaa aataaaaatt tgaagtttga tataattggg attcacaata ttgttgaccg
    26761 taatgaaata aagacagcac tagaaaaatt ccttgcttca aaagagggat aaatttaaga
    26821 tgataaggag gaatatttat ggagtttatt attagtttgc tgagtacacc tgctgttttg
    26881 cttggcgtag ttgcatgtat aggattgatt cttcaaaaga aatcagctgt tgaagtattt
    26941 acaggctctt caaaaacact tatcggtttt ttgatatttg gtattggtgc ctctgctatg
    27001 acaggagcac ttcaaaattt caataaactg ttccaacatg gctttggaat tactggtgtt
    27061 atagcttcac cagaagcagc tacagcactt gcacaaggta catatggttt tgcagtttca
    27121 tgtacattaa ttcttggatt catattaaat ttagtatttg cacgtattac aaagtttaag
    27181 aatattttct ttacaacagg tcatagtttg ttcttttctt gtgtattagt tttaattatg
    27241 aaagcacatg gatttgataa tacaatcact attttaatag gtggaactat cttagggttt
    27301 atgtctgctg cactacctca attctgtcaa ccatttatgc gtgaattaac aggtggcgac
    27361 gaacaagcta ttggtcactt taacatgatt ggttatggtt tatcaggtta tattgggcgt
    27421 ttattttcaa aacataaaga tgatacaaca gagactatag aatttcctaa gtggttatca
    27481 atattcagag acttcttaat gggtctatcc atagttatgt taatcttatt ttatattgca
    27541 acattaaaag ctggtcaagc atttactcaa gaaattgctg gttcaacaca ttggttggtt
    27601 tttccgctta tagaggcatt tacatttgtg gcaggtatgt caatattgat gtcaggtgtt
    27661 cgtatgttct tagctgaaat aactgcagca tttgtaatca tttcagaaaa gtatattcca
    27721 ggttcacgtc ctgcgctaga tgttccaacc gtatttccat atgcaccaaa tgcagttatt
    27781 attgggttta tatcagcata tgctgctggt ctattagcaa ttgctattat ggcatcattt
    27841 cctagtatat ttcctgtagt aattattcca gctgctcaca tatgtttctt ctcaggaggt
    27901 acagctgcaa tatttggcaa tacttcagga ggatggagag gggctattgc tgggtcattt
    27961 gttgtggggt tattacttgc atttttgcca gttatactat atccagttta tgggactctt
    28021 ggtatagaag gagcaacttt ccctaatatt gattacaacg tagttggttc gatattacat
    28081 aatattttac aatttataaa acctatttaa actaaattat ataaaagtat agtcatagtt
    28141 actatgattt caaggaggat acatcttatg gaaaatacat tatctgaatt tttagataat
    28201 atatctaatg aattgtcaga atttattgcc tcaatagatg agacatctat aaataaagca
    28261 tgcgaattaa ttcttgaagc tgaaaaaaat cacggacgtg tacatgtgac tggtattggc
    28321 aaaccaggac atgtatcggg atatatttca tcattgcttt catctactgg aacgtcagca
    28381 tatatattgc atggtacaga agcagtacat gggtcaagtg gtcaagtagt tgaaggagat
    28441 gttgttattg caatatcaaa tagtggtgaa actcaagagt taaaagcaac tcttaagact
    28501 ctaaaagtaa atggagcaaa gataattggt gtaagtggta atgagagttc atttttaaaa
    28561 aatatttctg atatattcct gtttgcaggt gttaagcagg aaggagattg tctcaataaa
    28621 gctcctcgtg cttcaatttt agctgaaaca ataatattac aatcattaag tgttgtatta
    28681 caatatgcta aaggtcttaa tacacagcag tatttgaagt ggcatccagc aggaagtctt
    28741 ggaaagtcta ttagagaggg gatataattt tatgaaatat aaagggatta tatgtgcaat
    28801 gataacacca tttgatgaaa atcaaaatat taattcacaa gcaacatgtc aattaattga
    28861 ttatttgatt gaaaagggaa tttatggatt atttattttg ggcactaatg gtgaatgtca
    28921 tgtattaaca gatgatgaaa aagttgaatt tgcaaagatt gttattaatc atacaaataa
    28981 tcgtgtacct gtttttgttg gaacaggggg taattcaact cgtgaagttg tagatttatc
    29041 taagagaatg gaagcgattg gagcaagtgc attatctatt attacaccat actttgttac
    29101 accaacacaa caggaattaa tcttacatta caaaactatt gctaattcag ttaatttacc
    29161 tattataatg tataatatgc caggtaagac tggaattaat attgaaccag agtcagtacg
    29221 tgaattatca aagataaaga atattgttgg aattaaggat agtagtggta aacttgacaa
    29281 catgaaagct tatattgaag caacgaagaa tgagaatttt agtgtgtttt caggctcaga
    29341 ttcacttatt ctggatagtc taaaagctgg tagtcaagga gctgttgcag caacaacaaa
    29401 cttcctcaca gagattggta tctctatcta tgaaaacttt atgaaagggg atttggaaga
    29461 agctcaaaaa gctcaaagta gtatagaaga acttcgacgt atactgaaac ttggaacaat
    29521 tccatctgtt atgaagaaaa ctattgtctt gaatggaatt aatgttggaa ctgcacgact
    29581 tcctgtaact gaaccaactg gggaagtact tgaagaaatt aaacgagtag ttgaaaatta
    29641 taggacaata cttaataaaa gtagtgagaa tagataatat aaatagggaa attacactgg
    29701 tatataatta atatatatat tataaaacat gactaaaatt aatgaataag taaagtggtt
    29761 tgatgagtat agaggtgata atatgaaaaa gatgaatata accaaaagaa tgtcagaatg
    29821 tggggctctt gcaattgtaa gagaagaaaa tcttaaccgt gcatgtgaaa ttgctgaagg
    29881 atgtataaaa ggtggtataa cagttataga aatgagttat accctaaata atgctggaga
    29941 aataattcaa gggcttaata aaaagtatgg tgaaacactt tgtgtgggag caggaacagt
    30001 tttggatagt gaaacagctc gtcatgctat attacatgga gctcaattta ttattgcacc
    30061 aaattataat gaaggtgtag cgaagatttg caatagatat cagattcctt atgctccagg
    30121 atgtacatca ttgactgagg cagtagacgc actaagttta ggagcaactt ttataaaagc
    30181 tttcccaata tcagatttct atggacctaa actagtaaag gtatttaaga caccaatacc
    30241 tgatatgcca gttttagcaa gtggagggat taatattgaa aacctacata tatggttaga
    30301 aaatggagtt gatgtatgtg gatttggtgg tttattaact aaaggttctg ttgaagatat
    30361 tgctaaaaat gctaaaaaga ttcgtgaaat cattaaaaat ataagaaaaa tttaacatag
    30421 ggctgtatca tagtatctta taattactat gatacagcct ttttaatatt attcaaattt
    30481 aaaacagttt acatttctat tatattacat ataatttcag taattttatc ttaatttttc
    30541 tatctggaaa aaaatgattt aaaacttaag ttatgatata atttcattaa aagaaggcga
    30601 tttttagtaa atatgagaaa ataatgtgtt tttaggggaa aagttaaata cagatttaag
    30661 tgaacaagaa tcgataatta agatattaaa tggtgaatag ggcatcaaaa aaattactaa
    30721 attaaaagtt ttagagggag aatcttagca agtgtgtgtg aaaattcaat ttcaaacaaa
    30781 aaataattgt aaatgaaatc aatttataca cgttgaagat tcacttttat cattatatta
    30841 aaaagcagag tgaattaaaa gtgagtctaa agataggagg ataattaaaa caatgaaaga
    30901 agacattagg ttacatcgaa tgtgtaaaaa agaacaagca acaaagaatg aagttatatc
    30961 agaggatatt ctaaaatcta tgagtattgg ggtcagtaaa cattttttag atgattcatt
    31021 tacaataata tggggaaata catcattcta tcaattatta ggatatacag aagaagaatt
    31081 tttagttaaa ttttctagtt taaaagatta ttatgaacag aatctttatc attttgaatc
    31141 tatgaaaaat cattttttag aggcttatca tcatggcgaa aagagtatag aatatcaaat
    31201 ttgcatttca gcaaataatg gagaccctgt ttgggtaata atgactggta tattaattga
    31261 atcacaagat aatgagaaat caatggtcta tatattgtat tcaaaaatta atgagttaaa
    31321 aataaagcaa gaagaactat ctgatatgga aaaagagagt acagagaatt ttaaatggat
    31381 gatgtcagag tatgctggga atgtttatat tagcgatatg gatacatatg aattactata
    31441 cttaaataag cactcatgca atactttaca ggcatcagca aatgaactta ttggaagaaa
    31501 atgttatgag gtaattcaag gtagaacttc gccatgtccg ttttgtacaa attcgtattt
    31561 aaaaaaagat gacatatatg aatgggaatt ttataataaa aaactgaaac gaacatttat
    31621 aattaaagac cgtatgttga attggcaagg gcgaagagtt cgtattgaat tatcttatga
    31681 tatgtatagt gctgaatata aattagcaaa aaaagatcag gaaagagaat caattttgaa
    31741 aactattcca gcaggaatgg ttagattaga tgcaagagat tatcttacta tactttggtg
    31801 taatgatata tttttgaata tgattgaata tacaaaggaa cagtttgcag aggaacttaa
    31861 taatcaatgt ggatatttat tttctgaaga ttataaacgt agtaagaaac tggcacaaga
    31921 tttgaaggag tctggggata atgttgtatt tgaagcaaaa atatatacac gttcaaggga
    31981 agaacgtata tggactgtta cattgtgtta tatcagtggg gaagacagtt gggatggaat
    32041 accatctttt tatagtatag gtattgacat aacaaaggaa agaaaacaga ttgagaaatt
    32101 acagcatata tcagagaaag atgcattaac aggaatttat aatcgtgctg agactgaaag
    32161 gcagattaag aaatattttg aaaaaaattt aaatgttatg ggtgcactgt ttatgattga
    32221 tacagataat tttaaacaga ttaatgatac agaagggcat atgattggag atatagtact
    32281 tactgagatg gcatcaggta tgaaaaaaat aatgcgtgac agtgatgttg ttggaagaat
    32341 aggtggagat gagtttacaa tttttatgaa gaatatttcc tcagttaaag atgcagaaaa
    32401 gaaagcagaa gaactattgt atatgttccg tcatctattt cagaaagaaa aaagttttct
    32461 aaaagtaact tgtagcatag gaatagctat atatccaaag gatggtacta cattcaagga
    32521 aatatatgca agagctgata aagccctgta tcaagcaaaa aatatgggaa aaaataatta
    32581 tgtaatctac aaccaagatt attttaaaga attagaagaa tttgattgtt cttctcttgg
    32641 tacagttatt gattcagaaa aacaatacgc tgaatatcct gataatctta cacgttatat
    32701 attccgtatg ctttatcaga ctgatgatat agaccaggcg attaatatga tacttgaggt
    32761 tgttgggaaa cagtttgatg taagtcgtgt ttatattttt gaaaatacag aagatggtag
    32821 atatacttct aatacttatg aatggtgtaa tgaaggaatc tcttctcaaa tggcttattt
    32881 gcaaaacagc aattatcaag actatgagga ttatgaaaag ctttttgagg atgaattagt
    32941 tttttattgt cgagatatcc atacattaag tcctaaacta gaagaattgt tttctagtca
    33001 aggtatccac tctacacttc aatgtgcata taaagaagat agagttttca gtggatttgt
    33061 tggatttgat gaatgcacag gactacgtct atggtcacaa gaggaaataa gtacattatc
    33121 attgatttct caaattatat caatgttttt acaacgtaaa aaaaataata aacttaatca
    33181 acagattcaa caataccaga atattttaga taatattgac cagtgtattt gtgtgattaa
    33241 taaagaaaat aattttttat tatatgtaaa taaaaaattt aaaaatacat attctaaatt
    33301 ccaaattgga caaccttatt atcttgattc tatagatatt cataagatat ccattatatg
    33361 gaataaaaaa gaagcatacc tatgtactag cacgatttaa tggtaaagta aagtttatat
    33421 tggacttaaa ttaaatttcg ttttaaataa gatattattt tagttgctta ctgaaaagac
    33481 tagaatctat attaatgaat tatactaatt ttataccact attaaaatat tgtttgctaa
    33541 aaataaaaaa tagccttaaa acagttgatt ataaaaaatt aactgcttta aggctatttt
    33601 tatctttgtg acgaaataga cacttgccat ttagaatgtg acaatatagt agttgtttag
    33661 aaaaggcaca aagcattata ctttaactaa agtaaaatgt attttgcttt tagaataaaa
    33721 acaattagga gggagctata attgaaaaag ataatatatg tattatttac aattgaacta
    33781 ttaatagtat ctttattagg tctaaatata gttaaagata atgaaattaa taatatttta
    33841 tataacgata caacaagtat atctgtaatg tttaaagatt ataaaaagtt aaataaaaat
    33901 tatagtaagt ggattaaaga tattgcagat gaaaataatg tgactatatc aaagtatgtt
    33961 tttaataata atgaaaaatt atctatatat acgactgata caagtttgaa taacaatata
    34021 aagttaaaat caggaaaatt tcctaatact aattcaaatg aatttattag taatataaac
    34081 actaataata gtaatcaagt aggtaaattc tcaactatga gtaaagacat atcaatttta
    34141 attagggatt ttggtaaaat aagtgaagtt ggagaatcag gaatcttgta tatttcaact
    34201 caaaatgaag atacaataaa taaaatatta agagaactaa atgtagacag aagtattttt
    34261 gtagcaagat tacatgatag atatgttaac tcaaatttat acttaaatcc ttcaataatt
    34321 agagatttaa tactaattat cctttgtttc ttggctacaa taatacatta ttcaattagt
    34381 gtgagtagag aggcttctat tttaagatta aatggatact ctaagctaga tataattgct
    34441 agagttataa aaaatatact tagaattatg attttatcat ctgtcacagc attattaata
    34501 tatataatct atattttaaa attaaatata ggtgttagag catgcttata ctttgctatg
    34561 ttttcgatta tatgtatttt gataaatatt ttgatatcta tattaatagt tggttttaat
    34621 agtagaagtt ctaaatatgt gctatctcta aatggaaaaa aatcttatgg ttttgtaaat
    34681 ataatgcatt tcacattgaa aattgtattt gtatcatttc ttatattatc cataaataac
    34741 tgtattttaa attataatat gctacaaact cagttaggaa atctatctga gtgggataaa
    34801 gcaaaaaatg tttataatct tactcttaaa gatacaggcg aacaatcttt aggaaaggaa
    34861 gaagtaatta aaaatgccaa gattaaaggt ttctataaaa atttggtaga agaaaaagat
    34921 gctttcttaa tagattcaac taattttgaa aaacttgaag atggaagtta catgtatgaa
    34981 ataaattcaa agggtaaaaa cccagaagta agtcaatatg gtaaaaatat aaaaataaat
    35041 aaaaactatc ttaaagttaa ccctatttac tcaaatggca aagaaatatt taatctaatc
    35101 gattatggcg ataagactat aaatttatta gttcctaaaa agttacaagt acatgaaaat
    35161 gagattaaaa aagagtttag agaattattt tattttgaaa aaatagaagt agaaaatatg
    35221 tacaataaag agttaaatag agagttaaat aaaacaaaga agtcagattt aaatgttaat
    35281 ataatatatg tagataataa tcaaagctat tttacttata actcccttgt tatggatgac
    35341 aataggaatc tcattgatga cccaatagca atagttgaca tagataatat tgatgattct
    35401 ttttatcttt cttatatatc tagatgtgta tattttaatt ctaagaaatt agatgccctt
    35461 gcagatataa gtaacattat tgaagctcaa ggtgtagaag cgcatatcca aagtttacat
    35521 gctgtttata atgagtatgg tttagaaata aataaactag aaaaatattt gaatagtgaa
    35581 atttttacta taataataat agcaatatca aacttaatga ttacctacaa tatagtagct
    35641 agctactatg aaagaaataa atataagtta tatattaaaa aaatatttgg ttattcaact
    35701 acagctagaa gtatgttgtt aatagtttca ttaatattaa caaacattat tccaataggc
    35761 attatatcaa caagagtaga tttaagtaat aatattatct tatttggact tctaatatta
    35821 gttatagaag taattgtatc tattgcatta gacaagatta tctcaaatag ttcatttaat
    35881 aaaattataa aaggagaaca ttaaaaagat gatttcatta ataaatatat ctaaaaaatt
    35941 taaagataaa tctataatag acaaatttaa cctggaaatt tctaagggcg agtttgtagc
    36001 gataacagga aatagtggtt caggtaagac aactttactt aatataatgg gattattaga
    36061 aaaacctaat tctggtgata ttataataaa taatataaaa aatccaaata gtaaacagat
    36121 aagaatttta caaagggatt tttatggcta tctatttcaa aattatgctt taattgagaa
    36181 tgaaaatgtt gaaaataact tgaaaattgc tttaaagtat caaaaaaata tcaaccataa
    36241 tgaaaaaata aattacgcac ttgagtctgt aggtcttaga aaatacaata aaaaaaagat
    36301 atacgaattg agtggaggag aacaacaaag ggtagcatta gcaagagtaa tattaaaaga
    36361 atgtgaagta atatttgcag atgaacctac aggtaattta gataaaaaaa atagagacat
    36421 agtatttgat atacttaaaa gtctaaataa gaatggtaaa actatcgtat ttgtaactca
    36481 tgatttagag ttatcggagc aggcagatag agttataaaa ttgtaataat atcaactata
    36541 ataaatataa gaaagagatt acagctaaat caagtttaat aataatacga atagaattta
    36601 aacattaagt aaattagtag tttgtaaata taagtataat atgatatcat aaaggctcaa
    36661 aagaaatttt atataataag aaatctaaaa ataacaaatg gaggacatat aaagatggaa
    36721 aatttaccaa attgcccgaa atgtaattca gaatatactt atgaagatgg aactctttta
    36781 gtttgtccag aatgctctca tgagtgggca ttaggattgg gagctgaaga agattcaaat
    36841 attatcaaag atgtaaatgg aaatgtatta aatgatggag attctgttac agtaattaga
    36901 gaccttaaag taaaaggaag ttcatcatct ataaagattg gaacaaaagt gaaaaatatc
    36961 cgtttaatcc atgactcatc agatggacat gatatagaat gtaagataga tggttttgga
    37021 gctatgaagc taaagtcttc tgttgttaaa aaagcgtaat attataaata agctgtagtg
    37081 tttattgttt ttcagtacag tataaaacca taagaatcta ttaagtaata aaagtttgtt
    37141 tatttatctt tatattttct tatggtttta ttaaatataa attttattga acaccaaaat
    37201 attctctcct ctacaaataa gccaatctta tttaaactaa tatactttgt actatttata
    37261 ctgaaattgt aaatttaaat gctatgttat ttaggtttgt atagttaatt tatatatttc
    37321 tgattttata aattgtattt attattatat cttgattcta aaatcattaa aaatttcaac
    37381 ttctataaag atttacaatt tatcaaatac attatgagta tataaacaat ttattattac
    37441 agtgctacat ttaaaataag tcttagtata aaggtattgt tacaagtata aagaaactta
    37501 tgtatgctat tggaataaat aataccttaa attataatta agaataagaa ctgttaaata
    37561 agggacttga ttatcattta gttatagata atataatatt aaaaataaag tttaagagga
    37621 gaaaaaatat gatagatata cataaaaata tatatgataa taagttattt gaggagctaa
    37681 agattgactg taagaagtgc tttggacttt gctgtgtagc tctttatttt tctgcttcag
    37741 atggatttcc tatcgataag gaatcaggaa aaccctgtat taatttacaa ccagatttta
    37801 aatgttctgt acataatagt cttatgaagc gaggttttaa agggtgtact gcatatgatt
    37861 gttttggttc aggtcaaaaa gtagcacaag taacatataa ggggatagac tggatgcaat
    37921 catcagaact aacaaatcaa atgtctgaag tgtttttaat tatgagacaa ttacatgaaa
    37981 tgttatggta tcttaaagaa gcatctgtat taaatatatc agatacaatc aaatcaaaaa
    38041 ttgatttaat aattgaagaa actgaaaaga taactaatat gggcccagaa cagataatta
    38101 atttggatat catatcacat agaacaaagg ttaatttatt attatcacaa gcgagtgagt
    38161 ctgtgatggg aaaggttaaa tcatttatca agacttctac tcttaaaaac atgaaaaaat
    38221 taagtaaaaa tatagattta ataggagcag accttagaaa aataaatcta ataggagcag
    38281 atttaagagg tagatttcta atagcagcaa atttaagaaa tacagatttg agtggggcaa
    38341 atttaatagg agcagactta agagattgtg atattagagg tgctaatctt gaaaatagta
    38401 tatttttaac acaattacaa gtaaatactg caaaaggaga ttctagtacg aagttaccag
    38461 cttcactaat acgccctaaa tactgggaaa aataattaaa ttaatacata attttacaaa
    38521 atatgaactt ttttgacttt aattcatatt atacattaga gattctttac aagaatttct
    38581 taatataata tagggagaga tataaaaatg agttatcaaa attataaatg tgaaagagat
    38641 tatgtgtatg atgattataa atacaataag tgcaacaagt gctataatga ttatgaggaa
    38701 atgacacatg ttcatgaata ttcagaaagt gttaagttag cagaagaatg tgaggataga
    38761 cataaccacc gtgcagcagg ggttactggt gaagctatac caataaatgg aggtacaaat
    38821 catgttcata aaataaatga taatgtagat ttccttgacc atttccataa gatatgtgtt
    38881 acaacagggc cagcaattag aatacctgga actgataaac acattcactt aatatgtgga
    38941 gaaactactg ttaatgatgg tcattgtcat aaattccttt ttactactca aatagaagca
    39001 cctttagtat aagctgatgt gaattattgt agtgaatttg ctagattata gtataataat
    39061 atataataga taatatttaa acttaatgag gactatgata tttaaccttc gtagtccttt
    39121 ctaagttttg tataaaaaag tgttatgcaa ttaaaagtga tatagggagg aaatttttat
    39181 gaaatctgga ataattcttg aaatgaaaca aataaattca acagaatatg acgaaatgtt
    39241 gcaagtctgg gaatcatcag taagagcaac gcatgatttt ttaacagaaa aagatattga
    39301 atctttgata ccattagttg aaattggact taaagaagta gaaaatatag tttgtataaa
    39361 agataatgat ataataaagg gctttatagg aatagataaa gataaaattg agatgctctt
    39421 tatagaagat aaatatagag gaaatggtat tggtaaaaaa ttaataaaat atgctataga
    39481 taaatacaat gtaaaatatg ttgatgtaaa tgagcagaat aaaaaagctg taggatttta
    39541 tattcactta ggatttaaag tgtttgatag gtctgaaata gatggacaag gtaacccatt
    39601 tccaatacta catatgaaat taatttaaag ttatacttct cacttattcg caaaaatatt
    39661 tacttaaatt tttatacaaa taaaagtcgt gacagtttta ggacacgact tttttactac
    39721 actattaaat tgaaatttat ctgttctata ttatgattat tagatgtagt ttttttattt
    39781 taactatgta cttaaatacc aagtataccc atacctatca agtacttcag cagcgccatc
    39841 attttgatgt ggtggtgggt gtggtaaaaa ttcttgtaca agtgtaccac cttcggcaag
    39901 ttttacagat atttcttcta tcgcttctcg agatggtaga acaacacaaa tcgccatgcc
    39961 agaaattaca acaggcttgt ctgtatccgc acccattata caaccttcgt attttgtgaa
    40021 agtaacactt gcgtgcataa taggattgtt tggattgctg tctaatcgcg caaatatagt
    40081 ttttcctcct ccgaaagcct cagcataaaa attaaatgct ttttcacaag taccattaaa
    40141 tattaaatat ggagttagca tgaccaatat atcctccttg atatagaata atttatagtt
    40201 gcacctgata atctaaatta tgatttagta aattgtatca tagggaaaac ttgaagtata
    40261 taatttttta ttattatatt atacaaattt attaatttaa aaaaatgtta tatgtacgga
    40321 aggtttacag gataaaatat aataaaaaga ttaaggtgac attataaaaa atgtatattg
    40381 acattgacgc tacgtaattg tatatacttt gtcttaaagg agatggtaaa tatgaatatt
    40441 atagaaattc gctcagataa aatatacaag aagataatgg atgcaccaat aaacaaaaaa
    40501 gaagatatat acagatatga attgatgaag ccttttgaat ttaagtggaa gtgtatgaat
    40561 gttccaatag ttgctagaca gaaaggtgga tatgatgtaa ttatagcaag tgaaatgtta
    40621 ggggttttat cgcctaagga tattgatgaa aagcaaaaaa agaatataaa tgtgttatct
    40681 gctgataaaa tttgggccac ttgtaaagaa accatagaaa actctataaa tgcttttata
    40741 aaagaagggt atgatttaaa cattaaggac tataaatatt caatattatt ggcgaatcca
    40801 aatagtcctt atacaatatt aagtgatgga tactggggtg atggtgggat tcctggatat
    40861 atatttctat cattggttcc taatgaatat actatcaata gattaccagt attaatagca
    40921 catgaatgta atcacaatat tagatttcag tttatagagt ggaataataa tgtaacatta
    40981 gaagaaatga tgataaatga aggtcttgca gaaaattttg caacatggat gtttggagag
    41041 gaaatgttag gaccttgggt cagtagaaca gatatcgaaa cattaaatac ttatataaag
    41101 ccaataataa aaagtgcttt aaaagaaact ggatttcaaa atataacatc ttatctttat
    41161 ggtgatgata tagctaaaat gcaaggatat tttccagtag ggttgcctta ttgtgcagga
    41221 tatgcttgtg gatattatat gattaagtat tatttagaaa agacaaataa atcaataatc
    41281 gaagcgactt tattgcctta tagtgagata atcgaagcag taaaagagtt ttgggaataa
    41341 attttataaa ttgcataatt tgaaataaat tatgcaatta ttttattttt aagaaaaaat
    41401 aaattgacaa taatttataa gaaatataca ataatatata taaagaaata tttcaatatt
    41461 taaaagtttt aagatttcat atctagagta cctaacatta catgttagtt tcttgttact
    41521 tatctaatta ctttatattt cgtagttata tataaaatta ctataaaaaa tgaaatatat
    41581 taaacaatca actaaaaaat gaaatattaa taaaaaaaaa ttcaaattat aaatattaaa
    41641 tgaatataat taaaacaaat atataaattt aagtataaca ctcacatttt aatgtattgt
    41701 gaaatttttg ttgaacttta tgtaccataa cttataaaat ttatgtcatg ttatatttga
    41761 ataagtaata aaattgtaga tgtaaattaa tctacaaaat ttatatgaaa tggagttgat
    41821 gctatgacag aattaatgat tataagtggg ttagtactat tgatttgtat aacttctagc
    41881 aaggtattgt ataaatttgg agtaccaata ttattgattt ttatcttact agggatgtta
    41941 tttgggtctg atgggatggt aggaatctat tttgataact atgaactgac aaaacaatta
    42001 tgttctattg gactaatatt tataatgttt tttggagggt ttggaacaaa ctggaatatg
    42061 gctaaacctg ttgctatacc ttctatatta atgtcttcac tgggtgtaat aattacggct
    42121 ggcgttacag gtatgttttg ccacatggta ataggaacta gtttacttga aggtttatta
    42181 attggggcaa ttgcagcttc aacagatgct gcatctgtgt ttgctgtgtt gcgttctcaa
    42241 aaactaaact taaagggttc acttgcatca ttattagaag ttgaaagtgg aagtaatgac
    42301 ccaatagcgt atatgttgac actaattctt ttgacattga tgaataattc tggggtagaa
    42361 cttattgcac caatggtaat aaaacaaata gcttttgggt tagctatagg atttatacta
    42421 gcaaaattat ctgtttatat tttaagacat tcaaacttcg agatagaagg attttatact
    42481 atatttataa cagctattgc aatactttct tatgcattta gcgagtatct tggaggaaat
    42541 ggatatttaa gtgtttacat ttcaggtatt attataggaa atagtaggat acctcttaaa
    42601 aaaagtttgg ttcatttctt tgatggaatt tcatggatta tgcaaataat gttattcttt
    42661 atgttaggat tgttatcttt cccttctaag ttaccaaatg tatttggtat agcaatggcc
    42721 atatctatat tcatgatagt tattgcaaga ccattagcaa catttatagt tctagcaaaa
    42781 tttaaattct caaataaaga aaaattattc atatcgtggg taggtcttag aggtgcggct
    42841 tcagtagttt ttgcaattta tgctgttact caaggagtag ccatagagaa tgacatattc
    42901 catataatat tttttatagc gttgctttca gtaggaatac aaggttcatt gataccaact
    42961 gtagccagaa agttggattt agttgatgat aatacacctg tattaaaaac atttaatgat
    43021 tatgatggag aaattagctc taaacttatc gaagtaaatg ttgatgaggg taataaatgg
    43081 gctaataaga gtataataga ttctaatata ccagacgata tattaatagt tatgataaaa
    43141 agaaaggaac aggttttaat acctaaaggt tcaaccatta taaaaacagg ggatattttg
    43201 gtattgagtg gagatagaat tgaagaatta atacaattat aatttatttt gtattgactt
    43261 taacctaagg ggaaagttta aacttaaatt aatcaaatct aatgcgcagg tgatgagatg
    43321 ttttctatag gaatgttttc taaaataaat aaaataacta caaagacatt aaggtattat
    43381 gaagatatag ggttgttaaa accagaatat gtagatgaat ttacaaaata taggtattat
    43441 acaacagagc aattacctaa attacatcag ataataactt taaaacaaat gggtttatca
    43501 ttagctgaga taaaaaaagc tgtagaaaat cctgaagaag ttgaaaatat tttaatgaat
    43561 aaagaaaaag aaatgttgga tgtaattaaa agtgaagaat ataaaataat taaactacgt
    43621 aattacctta tgaatttgaa aggagaagtc aatatgaatg atgtaattat taagtcttta
    43681 ccaaaagtta aagttgcttc tatgagaaaa gtgttaaagg ggtatgatga actttttaat
    43741 ctatttccaa atgtaatggc tgaagaaatg atgaaaacag ggtgtacatg tgcagttcct
    43801 gattattgtt ttaatatata tcatgatggt gaatatagag agactgatat ggatgttgaa
    43861 atgtgtcaag ctataaatga tttaaaggaa gatacggata tattaaaatt taaagaatta
    43921 gatgcagttg aaaatgcagt ttgtatatta cacaatggtc catattcaac attaggaaaa
    43981 acttacgcag atgcatttaa atggatagag gacaataaat ataaagtggt tggaaatcct
    44041 agagaatctt atatagatgg tatatggaat aaagagagtg aagaagactg gttgacagaa
    44101 gttcagatac cagtgaaacg catgttataa tatgtctaca aagtataaat aagaataaaa
    44161 aaggtggtgt ctcaaagtaa acattttagt ttatgagaca ctctttttca tatgaaatca
    44221 agtatatttt tataattacg attatgaaaa aaggcttatc tatattttta gacagcctct
    44281 tattttttta ttataatagt tttctaaaga tgctctattt ataaattttt attaaagact
    44341 ttataaataa ttgtatttaa tatacaaaat atatataaat attgatgttt tatatataaa
    44401 gttgtatatt tttttaagga tataaagtaa aaaaatatac aatatcaaga aaaaaagata
    44461 ttgggtattt aaagtaatac tttatttaat tttaagtaaa tcgggtatct acatatatag
    44521 atactaattt caaagaatag gagggtgttt atatggaaat attcgcaata ggacattcaa
    44581 attatccata tgataagctt attaatatga taaaaaaata tgacataaat tgtgtagttg
    44641 acattagaga aactccatat tctaaatata atattcaata caataaagag gcatttaacg
    44701 aatctcttag aaattccgga tttttatata tatacatggg aaaagaattt ggagttaaaa
    44761 gaactaataa agatgtatat acgcaagaag gttatgcaga ttttgagaaa gtagcaaaag
    44821 aagatatttt tttaaacgga atagaaagat taaaaaaggg ttgtcaaatg ggttatagga
    44881 tagttttatt aggagctatg caagaaccta taagatgtca tagaagtatc ttggtgggaa
    44941 aagtattaaa taaagaaggt tttgatgtaa aatatataat gcatgaagga aatttggcat
    45001 atcaggaaga tatagaggaa tcattattgg ataagtattt tagtgataga aagcaactga
    45061 gtattgacaa tttattaggg agtgcattaa cgagagaaga aatgatacaa gaaggttata
    45121 agctagctaa taaagaaata ggatatagaa ctgagaaact aggtaaataa aaatatacaa
    45181 gtagataaaa tacagtactt atcttaagta aaataatatt atgaatttat aatagctagg
    45241 catgatgtgc caattaaaaa tattctagtt atttaataat atcattaaat ttagggtatt
    45301 ttttaatagc acatcatgtt gcagttttaa aaaataaaat ctctaatatt gccataatca
    45361 actgttctat taagagtagg atgactagat ataaatctaa ctgtaatttt tgaatttaac
    45421 aaacaaggat ttgaaattaa aaatactcta tctccattga caatagaagt aatagctact
    45481 ggcaaaatat ctacaaatgt atcatatctg tttttagcaa tttgataagg ataatttcct
    45541 acaaaaacaa atagatttaa atcatatata ttatcagtaa accaagccca ttgaccataa
    45601 actttgtcga tattcattgt gcctaaacca agtgtatcaa agtatgttgc tatagttaaa
    45661 taaatatttt ccatgttttc taaatatgaa acagtatatc ttctgaaacg tatgggtgct
    45721 gtggaagaaa taggataaac catatttaca tttagattat ttgcatttaa attaaccaaa
    45781 gtatcacatc ctaaaattag tctataaaat acaatattta aatggatgcg attttgttac
    45841 atctaaagtg taatatttta tatattgaaa aagtggtaaa agtttggatg attaaataat
    45901 attataaaaa atatataaaa tgtacttatt gttattgcta cacgatagtg atacaatatt
    45961 aacgaaatat agctactttt aataataacg gaaaatattt atattaaatt aataaatatt
    46021 ttaaatgtgg tatccataaa aaataataaa cataagataa ttataaagat atactgtgtt
    46081 caaatgatat taaacaagat ttatattatt tgaaagcagt atattataat gcgaacaata
    46141 caattctaaa ctttgcattg tcaatttaca gttcgataaa ctaattaaaa attaaattta
    46201 tataaagagg gaaaagagga atagggatgt ttataaggaa aaatgttata aagttagcaa
    46261 ttcctataat gatagagcag acgtttgtca tgcttttagg agtatttaat acaatgatgg
    46321 caggtcatat tggggaagaa gctgtatctg cagttggaat ggttgattca ataaacaata
    46381 tatttatatc tgtatttgct gcactatctg ttggagctac tgttgttgta gctcaacaaa
    46441 taggaaaaaa agatggtgaa aaggtgaatg aaactattaa gcaggctcta gtgtctggag
    46501 taatattatc ctttacaata acaatattga tgtgggtttt tagaactggt gtaattaatt
    46561 tattttatgg ttccgcagaa gaattggtaa aatcaaatgc aaaattatac atagagttta
    46621 cattatttac gtatccattt attgcgacac aacaaatagc aaatggtatt ttaagagggt
    46681 gtggagatgt aaagaaacct atgtatgtga ctatgtttat gaatatagta aatgtaacat
    46741 taggatatat acttatatat ggtattgatt taaatcctct aggaataaat ttgcaaacac
    46801 catcctatgg cataacaggt gcagctatat ctattgctat agctagaata attggatgta
    46861 tagtaattat aagagtttta tttaaaggaa acgaatttat atctatgggt aaaatatttc
    46921 catttaagat tgatgttgaa actcaaaagt ctatatttaa tataggaata ccagctggag
    46981 ttgaacaact actttttaat gcaggtaaat tgattgttca agtatttata gttactatgg
    47041 gaacatcagc aattgcatcc aatgcaatag gaatgtcaat tgcatccata ataaatgtaa
    47101 ttgggaatgc tttagctttg tctgctacaa ccttggtggg acagtatata ggacgtggag
    47161 atattaaagg agctaagagt actttattat atttaactaa atttgcaaca atttgtttat
    47221 ttatagtagg agctatattt ataccaattg caccttggat ttcaagtatg tatactcaaa
    47281 atgctagtgt aattgacatc tcaacacaat taattcgaag tgattgttta gctatggtaa
    47341 tatggcctat atcctttgta ttatcagcag ggctaaaggg agccggtgat actagatata
    47401 caatgatgac tgcagtaata ggtatgtgga tttttagaat ttttacaggt tacgtattgg
    47461 gggttgtatt agaatttgga gtgttaggaa tttggatagg tatgtatact gattggcttg
    47521 ttagagggac tttatattgt ttaagattaa gaggaacaaa gtggctaaaa cacaaagttg
    47581 catagaatat atgaaatcac ttttagatgg ataactctat ttagaagtga ttttttatgt
    47641 agttattatc ataattataa gtatgatata taaggtgatt aaattacata aataaaggct
    47701 ataatagtat ggatattata aattatatat tgagcagaat tacataattt ggcgataaat
    47761 attagaaata tatatctata gaaaataata tatatgggta tattattaaa tataaaaaat
    47821 attaggtatt tatttaataa taaaggtggg tattgttatg ataaataaaa taggaaaaat
    47881 aactctctat gtaaataatc aagaggatgc aaagttattt tggacagaaa aattgaactt
    47941 tgtagtaact tatgaaaagg aaatgggtcc aaatatgaaa tgggtggaag tagcaccaag
    48001 taaaaatgaa tttacaacat ttgtgttgta tgataaaaat ctaatgatga agcaaaacaa
    48061 agagataaat gtatctcatc catcaataat tttaagtaca agagatatta atggaactta
    48121 tgaacaaatg gcaaataacg aggttgaggt tggggaatta atggagatgc catatggaag
    48181 gatgttttct tttaaagacc aagatggaaa tgattatttg gttagagagg ataaataatt
    48241 ttacaaagta ttaaatttac tcaatatctg atataattag agacaataat tattataaac
    48301 tagtctagga ttagaattat ataattaaaa attaagtgta aattttgagt agaggtgata
    48361 aaatgtttaa gaaaatggca gtactaaaag atatagcaac taaaataggt cgtaaaaaag
    48421 cgtatgaact attagaaatg gttgaaggta atgatgcctt tgtagctgag gtaaagataa
    48481 aaaagaatgg aatagaatct aaaaaagaag aaattatgtt aaaagataat caaaaaataa
    48541 tattagagta tatagaaggt taaattttaa atacatataa gttgatatac taaatttctg
    48601 agatgagttt acataaaact catctttttt acttttcaat aactttgttt tattatttaa
    48661 tatacatttt atctccttag agttgctgat atataaaaat tactgatata ataaaagaat
    48721 ggatattaat gtaatatttt atagaaaaga ggggtattat gcttgaaata aaaaatcttt
    48781 cctttaatgt tgagtctaac aatgaggaac taggaataat aaatgatgtt agcctttcat
    48841 ttgagagggg aaaacttatt gttatcacag gtccaaatgg tggaggaaaa tctacaattg
    48901 ctaagcttat tatgggaatt gaaaaagcta cgagtggtca gataatttta gatggagaag
    48961 atataacaaa tcttagtatt acagaaagag caaaaaaagg aataggatac gcatttcaac
    49021 aaccaccaag aataaaaggt atgacagttg aaaatttact tacacttgct catggaaaac
    49081 cattgtctac tgatgtatgt tgccaatacc ttacagatgt tggattgtgt tcaaaagact
    49141 atttaaatcg tgaagttgat aactctcttt ctggagggga aatgaaaaga attgagatag
    49201 caactctttt tgctagagat ttaaaggttt ctatatttga tgaacctgaa gcagggatag
    49261 acctttggag ctttggaaaa ctcaatgaaa gttttaagaa aatacatgaa gagtctaatc
    49321 agactataat cataatttct caccaagaaa gaatattaga gttagctgat gaaataattg
    49381 ttctacaaga tggttcagta aaaagccatg gaacaaaaga ggctatatta cctgaaatca
    49441 tgtgtcaagt taattcaagt tgtgaattaa tgaaagacat gaattaatta gaaaggaagg
    49501 caaattaaat gaacaaaata gatttaaatc ttttagaaaa agttgctgaa cttcgtggaa
    49561 ctccattagg agcatacaat atacgtaaaa atgggcaagg agtagagaga cattcaactg
    49621 aaaatgtaac tataattcct aaaactgata aacctggaat agatattata gtaaagccaa
    49681 atacaaaagg agaaaatgta catataccag taatagtaac agaggctggt gtacaggata
    49741 tggtatataa tgattttgaa attggagaaa atgcagatgt tgttataatt gctgggtgtg
    49801 gtatacataa ctgtggttgt gatgatagtg aacataatgg tatacataga tttttcttac
    49861 gtaaaggagc tcgcctaaaa tatgtagaaa aacattatgg tgaaggtgat ggagaaggaa
    49921 agagaatttt aaatccagtt actattgtca atatggatga ggattcatat tgtgaaatgg
    49981 aaacaattca aattaagggt gtagattcaa ctaaaagaga aatggatgca aacctaggta
    50041 aaggagctaa aatagttgta tttgagaaat tattaactca tggtaatcaa gttgcagaat
    50101 ctaatatgaa ggttatctta gagggtgaaa actcttctgc tcaagtagtt tctcgtacag
    50161 ttgggcaaga taattctaag caaaagttta atccttgtgt tattggggat tccctttgtt
    50221 ctgcacatgt tcaatgtgat tcaataatta tgggaaattc tcaaattagt gctatacctg
    50281 aaattgctgc aaatcatcca gatgctcttt tagtacatga agcagctatt ggaaagattg
    50341 caggagacca aatactaaag atgatgacat taggtcttac tgaagaagaa gccgagcaac
    50401 aaatacttaa ttgcttctta aagtaaatta aagattttat ttaatttaat ataattaata
    50461 tagtataata tagtgaataa gtctaaaata tttttatttt taggcttatt ttctttatgt
    50521 aagaaaagct attagagaaa ttatattgta attaggatgt ggaataaatg aaaaatttac
    50581 ttataagaaa tgggacaata atatctccaa cagatggtat caaatttgaa aaaagagata
    50641 tcttggtttt acatgggaaa atatatgcta ttggattgaa ccttaaagag aaaataagaa
    50701 aagaaaaatt acttacaaat aaagagttcg agataataaa tgccgataat atgtatattt
    50761 ccccaggatt tatagatgtt cacacccatt gttataagag aaaattacct acaggtatgg
    50821 attctgattc aattggaatt gaaaaaggtt ctacagttat atttgatgca ggtacagctg
    50881 gtccctcaaa ctactatgat tttaaaaaaa agtatatgga tgagtgtaaa acagaagtat
    50941 attctttttt aaatgttaca aatgagggac taaatatatt gaatgaatca acttctttag
    51001 atgttataaa ttttgacaag gttgagtcaa ttgtagaaaa aaatatagaa aagataaagg
    51061 gtataaaagt aaaagcgagt aaatttcaat ctaatgaaag tggtatagat ataattaaga
    51121 aatcaaagca agttgctaaa aaattaaatt tacccttagt ggtatatata ggagagtatc
    51181 catcatatat agatgaagta atgaatattt tgggaaaagg agatgtggtt acaccggtat
    51241 atggaaatag tacaaatgga atccttaaag aatctggcac attaagaaaa tcagtaataa
    51301 atgcaaagaa tagaggagta ttgtttgatg tatgtcatgg agtggaccaa tttgatttta
    51361 aagtttttaa aaaagcaata aagcaaggtt tagagcctga cctaataagt actgatatgc
    51421 atataaaaaa catgaaagac gtaaactatt ctcttttaaa tgttataaat aaaattatgg
    51481 aacttgggat atccctagaa aagtgtatag aaaaagtaac tgaataccca acaaagattt
    51541 tcgatttaca tggaaataaa ggcagaataa agattggtgg agaaggtgat tttacaatat
    51601 ttacaatgga ggagtgtaat gatattataa aagactacaa taataatgaa cttgttttaa
    51661 ataaaaaatt aagattgcaa tatactgtaa aatcatggat gaaaagcagt gaagtttata
    51721 gacatggata cgaaaatact ataataaact aaacaatagt gataaaataa taaatatatg
    51781 tttaaattgg tatatattgg ataaatatct aaggaaacaa caattaaaaa ataataattt
    51841 taggggaggt attttagtat gaaagcattt gttgataagg atgtatgtgt agcttgtgga
    51901 gcatgtatag gaacatgtcc agacgttttt agtatgagcg atgaagggca ttcagtagca
    51961 attgaaggag aaataccagc agatttacaa gatttatgta aagaagccga agaaggatgt
    52021 ccagtttcag ctataacagt taaatagagc tgtttaaatt tatttttaaa ataaatatat
    52081 aagatttaat tggtacttaa gctatagtat tagaaacttc tattactata gctttttaaa
    52141 atagataaac ttaatatata agatattact ttttataaat atggaggact gaaatatgaa
    52201 gaaaaattat gaaataatat tgtttgattt agatggaaca cttacagacc ctaaagaagg
    52261 aataacaaag tctatccagt attctttaaa tagctttggc atagaagaag atttggacaa
    52321 cttagaacaa tttataggac cgccattaca tgatactttt aaggaatatt ataaatttga
    52381 ggataaaaaa gctaaagaag ctgttgaaaa gtatagagaa tattttgctg ataaagggat
    52441 atttgaaaat aaaatttatg agaatatgaa agagatatta gaaatgctct ataaaaatgg
    52501 taaaatatta ttagtagcaa cttctaagcc aacagttttt gcagaaacta tacttagata
    52561 ttttgatata gatagatatt ttaaatatat agcaggtagc aatcttgatg gtacaagagt
    52621 gaataaaaat gaagttatac aatatgtact agacctatgt aatgtaaaag ataaagataa
    52681 agttattatg gttggagata gaaagtatga cataattgga gctaaaaaga taggtataga
    52741 ttctattgga gtattgtatg ggtatggttc ttttgaagag attagtgaaa gtgaacctac
    52801 ttatattgtc gaaaatgtag agtctataaa agatattttg ttataaatat cttttataga
    52861 caaaaatatt acaaaatggt gtcgcatatt taaaaatatg atattatagt taaggaagtc
    52921 atttaaaaaa gaggaggatg cacttaaaat gaaatctatt ttaattatgg gtggaagcga
    52981 cttcataggt tctgcacttg ctaagcgctt gattaaatgt gggtatcaaa ttgatatact
    53041 tacaaatggt aaaaaggaaa tagattataa tggttttaaa gaacatctaa tttgtgatag
    53101 aaaagttcga aaagatatgg aaaacattat cacaggaaga aaatatgatt acatatatga
    53161 tatgacagca tatacaaaag aagatgtaag taatctgatt gattttataa gcatggataa
    53221 cttaaaaaag tatatagtat tgtcagcagg agcagtatat aaagatagtg gaagaaatat
    53281 aaaagaagaa aatgagaaag gtgaaaatga aaactgggga aaatatgggt taaataaaaa
    53341 agaggctgaa gattttatta taaatagccc tataccatat ataattatta gaccaactta
    53401 catatatggt gaaaataata atttatatag agagtattat ttctttgaaa aaatagaaaa
    53461 aaatgaaaag ataccagtac caaaaggaaa acaagttagt aatcaattta tatatattgg
    53521 ggatttggta aaggtattgg aaagcataat gaaaaatcct catgtaagag aggcctataa
    53581 tgtgacaaat ccacagttaa tttcttggga tgaccttata tatacatgtg gagaaattat
    53641 tggcaaagaa cctataataa aatatgtaga tatggaaaaa gtagagttta gagaaagaac
    53701 gtatttccca tttagaaata tagactttaa tcttgatata aataagctta ttgaacatgg
    53761 gctttatata ccaaacgtgt tactaaaaga aggtcttaca gcaacatata aatggttttc
    53821 agcaaataag ccaaaaatgc atgacagaaa aatgaacaaa gttgagtctg taatgcaaat
    53881 agtttaaaaa aataaataag taggtagata ttttgaactc aaaaattaag tattttttaa
    53941 aattttttat cttaatattt attttgattt ttatatactc agttgcgata gagccgagtc
    54001 tattaattgt gaaaaaatat aatataagtg aaaatggagc attgataaaa aatgatacaa
    54061 ttgagagtaa atctgaaagt gtaaaagtag ttcaaatttc agatactcaa ataggtagtt
    54121 tttattcaac taagaatctc aaaaaagtag ctaataagat taacactttg aatccagata
    54181 taatagtatt tactggtgat ttaattgatt actccaataa aaatccaagt gtagatgaaa
    54241 ttacaactat tttatcaagt atgaatgcta ggttgggaaa attttcagta tttggcaatc
    54301 atgattatat gtataaactt cctaggtatt ataggcagat tatgaaaaat tccaacttca
    54361 atcttttagt aaatgaaaat aaaaaaataa aattaaaaga tgataaatat attaatatat
    54421 taggtgttga tgaaatatta aatggaaatc ctaatataaa atatctggag agtcaaatag
    54481 ataataaaag ttttaattta ttgttagcac atgaaccaga tttagtagat atgcttagta
    54541 aagatacaat gaatttagtt ctatctgggc atagtcatgg tggtcaaata agattaccta
    54601 ttaagggagc attagttact cctccatatg gaaggaaata tactaaaggg ttttatgata
    54661 taaatggaaa tcatttatat gtgagttcgg gtcttggaag tacaaagtta ccatttagat
    54721 tttttaatat accagagata atagaattta atattataat ctaacataaa atatttagaa
    54781 aatataattt tgctttttat aatatgtaga tgtatatact gtaaaaatgg attaaaccag
    54841 tagattgaat gaattaatag attaaattaa tatataaaat atttaagtta taattaatgt
    54901 attagacaaa ataaatacta ttaagaacta ttaaaatata gattaaagat aataacatat
    54961 aataaataaa aaagtaagat tgtgtagatt atataaagat tatttacaat taatacaatc
    55021 ttgctttttt atttaaaaat tttaattatt atttaaaatt ttttatcttc tctttatccc
    55081 atataaacaa tttctcagaa ttatttaaag caccaaatac atttctttta aaatcaggca
    55141 tctctttatt taaattagca ataagatttt ttatgtactc tctcctagta tgaccatttg
    55201 cagggcaggg atttgtgata ataggatagt tagaatcttt tgaaattttc ttagtcatat
    55261 actcttctat gtaaaccata ggtcttataa ctgttaaatc ctgtctgtct aggtatgtct
    55321 ttggggaaaa acaatttact ctaccctcat aaaacataga cattaaaaat gtctcaattg
    55381 catcatcttt atgatgacca agagctactt tattacatcc aagtttttta gcattatcgt
    55441 tcaaagcacc tcttcttaaa ttagcacata atgcacaagg attcttttct tgtcttatat
    55501 caaatacaat ttcttttatg tcagtttgaa attcataaaa aggaacattt atttctttac
    55561 acaatttatc tagtggagaa ttatcaacac ctccagtatt taatgttatg gctatcaatt
    55621 caaagttttg tggagaaaat ctttgataac ttttaagtat atgaagtaaa gttaaactat
    55681 cttttccacc agaaagtcca accgcaattt tatcattttc ttgtatcata tcaaaatctt
    55741 gtatagcctt acgagcttta cttagaagtt tttgtataga cattttatca ccatccttta
    55801 aaaatattaa atttaagatt tatttaagat ttacttataa aatacttaag tcttatactc
    55861 taaaattaac attatagcaa acataacaaa aaggagaaga tttaattatg aaaaaattta
    55921 aattaatagg agccattatt ttagtagtat ttataagtgt atttatatct aaagatagat
    55981 tacttaagaa agataacgat ccaatagtag ctgctcaaca tgattcagaa caagatgttg
    56041 aggcaaattc tcaaaataaa aatcactcaa atagtatatc aaatatatta ttggtaaaca
    56101 agacaaatgg aattagcaaa aactatactc ctgaaaatat tactaaggta aacatacctt
    56161 ttgttgaaga agcaacagag gaagaaaaac aaatggcagg agaacctgca aaggcagttg
    56221 aagatttagt taagcaagct aattcagaag gaatacagtt tttagggtct tcagcataca
    56281 gatcttatga tactcaactg gatacttata caagaagggt aaaatctcag ggacgagaaa
    56341 aggcagatgc atatgtagca aagcctggtt acagtgagca ccaaactgga ctttgtattg
    56401 atttaacaaa tccagaaaga tggtttgttg gaagtacaaa agaagctaaa tggttggcag
    56461 aaaatgctca caagtttgga tttataataa gatatcctga aggtaaagaa gatataacag
    56521 gtacagcata tgaaccatgg catattagat atgttggtaa ggatgctgcc gaggaaattt
    56581 attcaaaagg attaacttta gaagaatatt tacaaaataa ataatataaa tgtgtaaata
    56641 atttgtatta tattggaaat ttagaaatta ataaatttat agattacact aactaaaata
    56701 tagtataatt ttatatgaat aaagctatat acaaagatta agttaggatg tgtaaaaatg
    56761 aataatacag ttcttgttgt ggatgatgaa aaggaaataa gagaccttat agagatatat
    56821 cttttaaata gtggatataa tgtaattaaa gctgaagatg gaaaagaggc tctagatatt
    56881 ttaaaaaagg aaaatattca tttaatgata ttggatataa tgatgcctaa aatggatggg
    56941 atagaagttt gtagaaaagt tagagaaagt ttgaatatac caatacttat gttaagtgca
    57001 aaatcagaag acatggataa aatacaaggg ataatgactg gtgcagatga ctatttgaca
    57061 aaaccattta acccacttga acttactgtg agagtgaagt cgctgattag aagagcatat
    57121 tattttagtg gtgctaataa tgaagataaa gatgtcataa aggttggagt agtaattata
    57181 gataaggaaa aacatagtgt aacagtggct ggaaatgaaa taattttgac atcaagagaa
    57241 tttgatatat tatatttact agcaaataat aaaggcagag tatatagtac agaagaaata
    57301 tttgaaaagg tatggaaaga gaaatattac caatctaata atactgtaat ggttcatatg
    57361 agcagaataa gagataaaat tgaaaaatat acagatggag aaaaaataat tcatactgta
    57421 tggggagtag gatataaaat tgaaaaataa aagtttatta aatcatatgt ttcgacccat
    57481 attagatctt ataataagct gtgctttaac ttcaatgctt attttaacaa gtatgtatat
    57541 aataaaatca ttatatgtca atagtgatat gtctgtagtt aatcaacttg tatatcaagc
    57601 aagagatttc agaagtctta tagggtatga tttattttat ccatttttat ttacaatcac
    57661 atcattagca atttattcca ttatatcgta caagagaaat aagcaaattg tagattttat
    57721 aagaaagact aatagaaaaa atcaaaaatt agaaatcatt aaaagtgctg taaatttaat
    57781 ggatgaaggt aacttagaaa aaagtataga tattgagtat gatttagata tattaaagga
    57841 taaagaaaag gatgatattg atgaactagc acataaaatc aataatatag tccatcaact
    57901 tagaaatata actattgaag agagacaagc tcagcagaca aaaacagatt taataacaaa
    57961 tgtgtcacat gacttaagaa cacctttgac atccataatg ggttatttag gagtgataga
    58021 agaaggtaag tataaagatg aagttcagat gatgtattat gttgatattg catatgaaaa
    58081 atcgaaaaat ttaaatgttc ttataaatga tttgtttgaa ttgactaaaa tgcaaaataa
    58141 tacaataaaa ttaaacaaaa tagaaataaa tttagtagag ttattaagtc aagtagtatc
    58201 tcaatttgaa atttatttta aacaagaatt tatggttagt agaattaatt ttaatgaaga
    58261 aaaattaatt gtaaaagctg atccaaataa attggtaaga gcatttgaaa atcttataac
    58321 taatgctgtg aaatatggaa aagatgggca ttatgtagat atagtcacag agaaaaagga
    58381 agatatggcg gttgtaaaag tgataaatta tggggaacca attccagtgt tagatttacc
    58441 aaatatattt gatagatttt atagagttga aaaatcgaga aatagaaatg ttggaggttc
    58501 tggattgggt cttgcgatta caaaaaatat tgtaaattta catgatggag aaattactgt
    58561 ttcaagcgat aaatatcaaa ctatgtttga agtacaactg ccaataatac aatcagctta
    58621 gttataaaat aaaagtacga ttatgtgata taaatattat aacaataaag tgtttacaaa
    58681 aataaaaaag taatatataa tttaagtcag tttaataaga tacttatcaa gagttagggg
    58741 agagagttag ctcagtgatc ctataccaac cttttatcag gtggtcctgc taacaacgat
    58801 gagatgactt gaaataatat actcttctta tcaataatag ataggaagag ttttttttag
    58861 aattaatgta acaaatttta aagtataatg gaggattaaa taatggaaaa agtagaaagt
    58921 tttaagctag accatacaaa agtaaaagct ccttttgtaa gaaagtgtag tgtacttgat
    58981 ggagtaaagg gagataaagt aactaaattt gacttgagat ttttacagcc aaatgtagaa
    59041 agttttggaa ctgctgctat gcacggttta gagcatcttt tagctactta tttaagagat
    59101 acattagatg gtgtaataga cttatctcca atgggatgta gaacaggatt ttatttaata
    59161 ctatggggag atgtagatgc caaaacagtt aagattggtt tagaagaagc attaaaaaaa
    59221 gttcttgaat cagataaaat gccagcagct acagctatag aatgtggaaa ctacagagac
    59281 ttatctttat ttggggcaaa ggaatatgca aaagatgttt tagataaagg attttcttta
    59341 aatatatatg gagaataatt taattggaag agaagatata agcataaatc aaagtgaagt
    59401 tttaagatat ttacaataca gaggtcaaga gatagataaa gaccttaaat atactattga
    59461 tgaatgtgta gctataacta aaaataaaat aaatcctaga tatttatcta ggatttatcc
    59521 tattaaaata aataaagata atgttgtaga attagaggga acaaatttaa cattagagag
    59581 taaagatgta tatgaacttt taaaagaatg taatgagtgt gtaattatgg cagctactat
    59641 agggatagat atagaaaaag aaataagacg acactcttat tcaaatttaa caaaaggact
    59701 aataattgat tcatgtggaa caacagcaat agaagaagtg tgtgacattg ttcaaaataa
    59761 tttagaaaag gtttttttaa agcaagataa atttataact atgcgatata gcccaggata
    59821 tggagattta ccaatagaaa aaaatataga tatattaaac gttttgaatg ctcaaaaaca
    59881 aataggtcta acaattactt ctaatggaat tatgataccg agaaagtcag tagtggctat
    59941 tataggtatt tctaatacaa gaataaataa atctaagaaa gaaaagtcgt gtgaaaattg
    60001 taaaaactat agaaactgta catatagaaa aggagcgaac tcttgtggaa ataagacaat
    60061 atctgaaaaa taatatatta atatttgatg gtgcaatggg aacaatgctt caacaaaaag
    60121 ggttaaagtt aggtgaaaat ccagaagtat ttggtcttca aaatccagat aaacttatag
    60181 aaatacatac agcatactta gaggcaggtt cgaatgtaat tcttacaaat acttttggat
    60241 gtaatgaact aaaattagat agtaagtata ctgtagaaga agtgattgac aatgctgttt
    60301 tggtggctag aaaagctata gaaaatgtag ataatactaa accaagatat gtagctttag
    60361 atattggtcc tataggagaa atgctagagc ctatgggtac tttaagtttt gataaagcat
    60421 atgaaatatt taaaagacaa gtactacaag gcgttaaatc tggagttgat gtaatagtaa
    60481 tagagactat gatggattta tatgaagcta aagtagctgt attagcagca aaagaaaact
    60541 ctgatttacc tattttctgt actatgacat ttgatgaagg tggaagaagt tttactggat
    60601 gtatgccaga atgtatggtg gctactatag aaggtctagg tgtagatgca ataggagtta
    60661 attgttcatt aggacctaaa caacttttac caatagttga aaaaatagca tcaagagcta
    60721 cagtccctgt tatggttcaa gcaaatgcag gtcttccaaa tatagttgat ggagaggcta
    60781 tatatgatgt tgatgcaaaa gaattttttg aaggggttaa aaagttcgtt gaagttggtg
    60841 ctactataat aggtggatgt tgtggtacga atccaagttt tataaaagaa atatctgaga
    60901 atataaattc tgttacaaag ggatgtatcg agaaaattga taaatgtgta gtctgttcac
    60961 catcaaaatt tgtggaagta caatcgccta cagttgttgg agaaagattg aatcccacag
    61021 gtagaaaatc tctacaagaa gcattaaaaa atgaaaatgt tgattatgct ataaatttag
    61081 gtttagaaca agtaaatgct ggagcacaaa tacttggagt aaatgttggt cttccagaga
    61141 ttgatgaaaa aaaactaatg ccaaaattaa taagagagat tcaagcagta gtagatacac
    61201 ctttacaagt tgattcttcc aatgtagagg ccttagagca aggacttaga tattataatg
    61261 gtagaacaat agtaaactct gtaaatggca aagaggagtc tttagaaagt atattaccaa
    61321 tagttaaaaa gtatggttca tgtgtggttg gacttacact tgatgaaaag gggataccta
    61381 aaaaggctga agaaagattt gaaatagcaa aaaggatagt taatagagca gtttcttatg
    61441 ggataaaacc aaaagatata tttatagact gtttatcatt aactgtttca gcacaacaag
    61501 aagaagcaat agaaactata aaagctataa caatggtaaa gacactagga gtaaaaacta
    61561 tattaggtgt ttcaaatatt tcatttggtc ttccaaatag gaaagcactt aatgcttctt
    61621 ttctaacatt agctttaggg gcagggcttg atttagcaat tataaatcca aatgaatata
    61681 gtatgatgga agctatcaat tcttttaaaa tattaaataa cacagataaa ggatgtataa
    61741 actatataaa tcaatatagc aatataaata attcaaaaaa gtcggattca tctacaaaga
    61801 ttgataaaga tttgcccttg gatattttag ttgaaagagg attaaaagat gaagcaaaaa
    61861 atgtaacact gaatctttta aaagagaagg atgaaaatta tatattagat gagattttaa
    61921 ttcctgctct tgataaagta ggaaaaagat atgatagtgg agatatattt ttaccacaat
    61981 tgattcaatc agcagaaacg gtaaaagttt cattaaatac aataaaggaa actttattaa
    62041 gtaaaagtag caataatgta tccaaaggaa aaataatagt tgctacagta aaaggtgata
    62101 tccatgatat tgggaaaaat atagtaaaaa taatgctaga aaattatgga tatgaggtta
    62161 tagatttagg taaggatgtc cctattgaag aagtagtgga agttgctaaa aatagaaata
    62221 taaaattagt aggattaagt gcacttatga ctacgactgt tcaaagtatg aaagatacaa
    62281 ttcaggcact gagagataat gagataaatg caaaggtatt tgtaggaggt gcagttttga
    62341 cagaagaata cgctgaagaa atgggtgctg attattattc aaaggatgca aagtctgctg
    62401 ttgaaatagc aaagttaaat ttttagcata taaattaaaa taaaggtttt actaaatagg
    62461 atattttata tataatataa atataagttt tagatactta tgtttaaaac aataggaatt
    62521 aatctataat aatgagatta attaatataa aaaatattta tcatcaacat taaaaagggc
    62581 tgggaagtct ggtataactt ccatcagccc tttttagtta aaatcatatg ttaaaaagcc
    62641 caattaccat ttttaaaaat ctgtatttgc tttccatcat aagtctcacc aataatatcc
    62701 atatcagcag aaccaatcat aaaatctaca tgtgttaaac tatcatttac accatgttca
    62761 tccaattctt catcttttaa attgtttcca ccttccagac aagtcttata agcagaacca
    62821 attgcaaagt ggcaagaagc attttcatca tatagagtat tataaaaaat tatatccgta
    62881 ttggatattg gcgagttgta tggaacaaga gcaacttctc ctaaataatg agagccttca
    62941 tccgtttcaa taagtttttc tagtgtatct agtccctttt cagcagagaa atctattatt
    63001 ttaccatctt taaatgttaa gaagaaattg tcaattatgt ttccaccata aacaagaggt
    63061 tttgtactat aaacagttcc atttacttta aacttatgtg gcattccaaa aatctcttca
    63121 gttggaatat tcggattaaa acttattcca ttagggtctt tggatgctcc acttagccaa
    63181 acatgaccct ttggcaagtc tagagtcaaa tcagtttttg aggatttata ttttaaagtt
    63241 ttaaagttat ttttatttag aaagtccatt ttagatttaa gattttcatt atgttcttcc
    63301 catgctttta tagggtcctg accatctact cttgaacatt taaatatagc atcccacagt
    63361 ttttctattg ctttatcttc tgataaattt ggaaacactt tttttgccca atcttttgtt
    63421 ggcacagaga ctatactcca tttacattta tcagttagag tgtaagaacg ccattctttt
    63481 aaagcttttc cagatgcctt ctgaaaattt gcaactcttt cagggtcaac atcttttaat
    63541 aaatctggat tttgggcata gactgataaa aatgccccac cttcttttgc tatatctaca
    63601 tattgttctg ctgtccattt ggggaactca tgaaatgctt catctggagc atataagtat
    63661 ttaataagag tactttcttc atcagaccac tctatataaa catttttagc accacattta
    63721 tatgcttctt taagtgcatt tcttgcaaaa tcagcacatt ctattggtga ctttataagt
    63781 agaatttgac ctggctgtat gttaactcca acttttattg ctaattcagc gtatttttct
    63841 aaatttctat ttaaattcat atttatcctc ctatattttt aatattgaat aacttataaa
    63901 gtattataac attacttatg tttttaatat tgaacaactt ataaaatatt ataactttac
    63961 ttagattttg ggtcatattc aaaatattta tactttatag attgagaaat aaaaaaaata
    64021 ttttaattaa aacaaattat gaggataaca aacttattta agcagtatgt tttttgttga
    64081 taataatatt aaagtagaaa taaaaatact tttttagtga aaagctatac aagaataccg
    64141 aaaaaaactt ataatataat aatgagatag atatttataa atgaaaaaaa atttttctgg
    64201 caaagcttaa ttaaaaaggt aatagctagt gttgttattt aaattagcat agaaaatcaa
    64261 ataaaaaaat tatgctaatg tatagacatt gataaggtag aatttaagcc ttttgaatgc
    64321 tatattaaac tagagtagat attcttatga atttcaaaat agggcaggag gaaaaaggaa
    64381 ataaaactat aaaaaatata aagtatttat ataaatttat agagtttata cgtcagaaga
    64441 tttcagttag gagggcataa atggagcttt atgaagccat tttttataga aaatctgtaa
    64501 gaaatttttc cagtaagaag ataaaaaagc cattgatgga agaaataaaa agaagttgta
    64561 aaaatttaga atacttaaat gaagatttaa atattaaagc acatgttgtt gatagaggtc
    64621 atataataca ttttttgatg ggtaaggaat gtaaagtaaa ggcacctcat tatatagtag
    64681 ttacatcaga caaaggtgag gactatttac agaatatagg atttgctaca gaaggtgtag
    64741 ttttgcgcct tacaacattg ggaatagcta cttgctggtt ggaaggaaac ttaaagagag
    64801 aagatatctt ggaatttgta gatattggga ataagaattt tgaagaagat gaggaagatg
    64861 atttagatta tctagctgga ataaaaacag aagaagatga tgaaaacaaa atagaaaatc
    64921 cttatataat aatagcattt ggatatccag caaaaaatga agagttgttt aggacgagat
    64981 atgctagacc tgatagaaag ccagtaaaag atatgataaa taagataaat aggaatagaa
    65041 agtggaaaga tatcttagaa ttgacaagaa gagctccatc tgtaaaaaat tctcaaccgt
    65101 ggtatttcca taaggatgaa cgaggtcttc atttatttga aaagagacct aagaaacact
    65161 gtgaagatat gaataaggtt agcttaggtg tagccttaag acattttgat atagcttgta
    65221 taaaaaataa aatagatgtt tcatatgaaa aacttcctat aaggaataaa ataggaaaat
    65281 catattttat aactgtagtc gagcatgtga aaccagaaga agaaacccaa gaagaaaatg
    65341 taactctaga aaaagaagaa tcgcaagatg aataaaattt tggaagggga tattggatat
    65401 gtataagtgt ggaaaatgta atcttagagg ctgttctaat ggaaatatgg ataaattaat
    65461 gaagatatgt ccaactagag aaattgaact acaacaaaaa gcaaagcaac tttatgaaga
    65521 agaagagaat agaaaaatag cttataatgc tggattagtt gaagcagagg ggtattgtca
    65581 atatactaga ctaaaagaga ttatagagtt tgctaaaaag tgtggttata aaaagattgg
    65641 catagcattt tgtattggac taaaaagaga aatgcaaaca gtgcaaaaaa tatttgaaca
    65701 tcatgggttt gaagtatttt ctgttatatg taaaaatggg gcaatgccta agagtacaat
    65761 tggactagaa gcatctcaaa caatatcaaa gtgttcagat gaggtaatgt gcaatccaat
    65821 aggacaagct ttatttttaa atgaagctaa ggttgacctt aatgtaattc ttggattatg
    65881 tgttggtcac gatactttag ccatgaaata tatggaagct cctataacaa ctttagttgt
    65941 caaagataga gtaactgggc ataatccagt tgctgcaata tataatgcag aatcatattt
    66001 tgagaaaaaa ttgtttgata aagatgaaga ataattcaaa gacttattga cataaaaagc
    66061 aattagtggt ttaattataa aaaagataaa actttaaatt atcctataga tacataaagt
    66121 tatataaata aagaaaaata ttacagctaa attccttaaa gtagtccaga gagactaaag
    66181 ggttatagat aatgttagta tataacctct agtaaatctt ctagaggttt ttgatgagta
    66241 taaaataaaa atttaaatat aataaagtct tttaaactag tccagagaga ctgggaaaga
    66301 tatctcatag ctaatgaata gagttatgta tagataaaat ccttatgcct cttttggtgt
    66361 gaggattttt ttatgattat ttaggcttta ttaaaaagga gatgtaaaaa tgataaatgg
    66421 taaagaaaaa ttgatagttg caattgatac tgacgaattt gataaagcta aagaactaat
    66481 agacagatta gaagatagtg tagacatatt taaggtaggg ctagagcaat acgttgccac
    66541 aaaaggtaaa acaatagatt atcttaaaga aaaagggaaa aaaatatttt tagaccttaa
    66601 attccatgat ataccaaata ctatgaaaag tgcagtgaga gctgcagtga gagataatgt
    66661 ttggttaatg acaatacatg tatcagatat ggaaggaatg agacaatgtg cactaattgc
    66721 tagggaagaa gcagaaagat taaatataga aaagccatta gtagttggag taacagtttt
    66781 aacttcatta agcaaccaag atttacagga cataggatgt aatatgacaa cagaagagtt
    66841 agctataaag agagctaaac tggcaaaaga atcaggaata gatggggttg tttgttcagc
    66901 gcaagaagta gataaaatag tagaagcatg tggaactgat tttataacag tttgcccagg
    66961 aataagacct aaatcagcag aggttggaga ccaaaaaaga gttgtaactc catcagatgc
    67021 aataaaaaaa ggtgctcatt atttagttgt tggaagacct ataacaaaag cagaaaatcc
    67081 aagagaatca gctattaata ttgtaagaga aatagaaaat gcttagataa aatatttggg
    67141 aggtagctta tatgaagggg aaattaattt tagaagatgg aacagtattt gaaggaaaag
    67201 catttggata tctaaaggaa gctattggag aagttgtatt taatacttca atggctgggt
    67261 atggagaact attgacagat gcaacttatt atggacaaat agttactatg acttatccac
    67321 ttataggaaa ctatggaata aatttagaag atgttgaatc aaataaggtg caagtaaaag
    67381 gacttattgt aagagaaaaa agtgataacc caaataattt tagatgtgaa atggatatag
    67441 acacatatct aaagcaaaat aaggtaatag gacttgaagg aatagataca agagcattaa
    67501 ctaaaattat tagaaacaat ggaactaaga gaggaattat aactttagaa aatgtatcat
    67561 tacaagatgt tcagtctaaa ttagaagagc attgtaacaa agattcagta aaaaatgtta
    67621 caagaaaaga aattgaaaat ataaaaggta ctggagctaa agttgtagtt atagactttg
    67681 gtattaaaaa tagtgtacta gagtctctta aagcttgtaa ctgtgatata actatagtac
    67741 cagcaatgac tacagtagaa gaaattttaa atataaatcc tgacttaatc ttattatcta
    67801 atggcccagg aaatccagag gatataaatg atatagttga aaatataaaa aaattaatag
    67861 gcaaaaagcc attgacagga ataggtttag gacatcaaat tttagcattg gcattaggag
    67921 gaaagacttc aaagcttgta tttggacata gaggaggtaa tcacccagtt aaatgcttag
    67981 aaactggaaa ggtatttata acttctcaaa atcatggata taatgtttca gaaatgccag
    68041 aaaatacaga agtaactcac ataaatttaa atgacaatac tatagaagga atgagacata
    68101 aggaattacc aatatatagt gttcaataca ttccagaata cacaacaaaa gaagatttag
    68161 attgtatatt taataaattc ttagcattaa tatagattta gtattattta cagatagtaa
    68221 aaaccattta gataaggaga aaaatttatg cctaaattag atagtataaa gaaaacttta
    68281 gtattagggt caggaccaat aataataggt caagctgcag agtttgacta ttcaggaaca
    68341 caagcttgcc agtctttgaa agaggaagga attgaagttg tattaataaa tagtaatcca
    68401 gccactataa tgactgataa agaagtggca gataaaatat atatagaacc attaacaata
    68461 gaatttatag aaaaaataat agaaaaagaa agaccagaca gtttacttgc aggtatgggt
    68521 ggacaaacag ggctaaatct agcagttgaa ctttatgaaa aaggcatact agataaatat
    68581 ggagtaaaga taataggtac ttcagtagaa tctatcaaaa aaggtgaaga tagagatata
    68641 tttagagaag taatgaaaga aataaatcag cctgtaatag ttagtgatat agttacagat
    68701 ttacaagcag gtcttgatta tgcacttaca attggttatc cagtagttgt aagaccagca
    68761 tacacactag gtggaactgg tgggggtata gctgataatg aggaagaatt aagagaaata
    68821 ctttcacatg gtctacaatt aagtcctgtt ggacaagtat taattgaaaa gagtataaaa
    68881 ggttggaaag aaatagaata tgaggtaata agagattcaa agggaaattg tatagttgta
    68941 tgtaacatgg aaaatataga cccagtcgga gttcatacag gagacagtat agttgttgct
    69001 ccaactcaaa ctttaagtaa caaagaatgt gcaatgctta aaaaagcatc tttagatata
    69061 ttaaatgcag tagaagttca aggtggttgt aacgttcaat ttgcacttaa tccacatagt
    69121 tttgaatatg cagttataga gataaatcca agagttagta gatcatcagc tttagcatca
    69181 aaagctacag gatatccaat agctaaagtt tcgtcaaaaa tagctttagg ttatacttta
    69241 gatgagatag aaaatgcagt aactaaaaaa acttatgctt gttttgaacc aactatagat
    69301 tatgtggtgg caaaaatacc aaaatggcct tttgataaat ttaaaaaagc aaatagaaaa
    69361 ttaggaacta agatgatggc aactggtgaa attatgagta taggaagtaa ttttgaggct
    69421 gctattctta aagggataag atcacttgaa acaggaaaat attcattagt tcacacacca
    69481 tctgaggaga gaagcataga ggaattaaag aaaagagttg tagtacctga tgatgagaga
    69541 ctatttgatt tagctgaaat gataagaaga ggctataaag tagaaatgat agaacaaatt
    69601 acaggtatag ataaatggtt tataaataaa tttaaatgga tagtagagca agaagaaaaa
    69661 ttaaaagtta tgaaaattga agatttaact aaagactatc ttcttgaatt aaagaaaaag
    69721 ggattctctg ataaaggtat atctgaccta atgaagataa gtccagaaaa attatatgaa
    69781 ttgagaagtc tatacaatat aaaaccagca tataaaatgg ttgatacttg tgcaggtgag
    69841 atagatgcta tatctcctta ctattattca acttatgagc aatatgatga ggtagttgtt
    69901 agtgataaga aaaaggtgat agtattaggt tctggtccaa taagaatagg tcaaggtata
    69961 gaatttgact attgttcagt tcactgtgta aaatctttaa gaaaaatgga catagaaact
    70021 ataatcataa acaataaccc tgaaactgta agtacagact ttgatacatc agataagctg
    70081 tattttgaac cattaacaga agaagaagtt ttaagtataa tagaaaaaga aaagccagaa
    70141 ggtgtaatac tacagtttgg tggacaaaca gctataaaat tggctaagtt tttacatgaa
    70201 aaaaatatac ctatactggg aacagatttt gatgatatag atgcagcaga agatagagaa
    70261 aaatttgatg atttactaga gagactagat ataaatagac caaaaggaaa gggtgtatgg
    70321 tcacttaacg aaggtattga agttgctaat gagttaggtt atccagtatt agttagacca
    70381 tcttatgtac ttggtggtca aggtatggaa ataacttata acgaagaaaa attatctcaa
    70441 tacctacaag atgcatttga tagagaccat aaaaatccag tacttataga taaatatcta
    70501 actggtagag aaatagaagt agatgctata tgtgataagg aagatatatt gatacctggt
    70561 ataatggaac atttagaaag agctggagtt cactctggag atagtacaac aatgtatcca
    70621 agtcaaaata t
//
LOCUS       DAEOTL010000010        69738 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEOTL010000010 DAEOTL010000000
VERSION     DAEOTL010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.010"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            150..1058
                     /locus_tag="KRH82_000933"
     CDS             150..1058
                     /locus_tag="KRH82_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBG8654226.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            1063..3432
                     /locus_tag="KRH82_000934"
     CDS             1063..3432
                     /locus_tag="KRH82_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBG8654227.1"
                     /translation="MSRGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            3757..4560
                     /gene="proC"
                     /locus_tag="KRH82_000935"
     CDS             3757..4560
                     /gene="proC"
                     /locus_tag="KRH82_000935"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBG8654228.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            5158..7914
                     /locus_tag="KRH82_000936"
     CDS             5158..7914
                     /locus_tag="KRH82_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654229.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYENSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            8046..8525
                     /locus_tag="KRH82_000937"
     CDS             8046..8525
                     /locus_tag="KRH82_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654230.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            8541..8963
                     /locus_tag="KRH82_000938"
     CDS             8541..8963
                     /locus_tag="KRH82_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBG8654231.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            9003..9794
                     /locus_tag="KRH82_000939"
     CDS             9003..9794
                     /locus_tag="KRH82_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8654232.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            9787..10587
                     /locus_tag="KRH82_000940"
     CDS             9787..10587
                     /locus_tag="KRH82_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBG8654233.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            10635..11690
                     /locus_tag="KRH82_000941"
     CDS             10635..11690
                     /locus_tag="KRH82_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBG8654234.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(11869..13815)
                     /gene="feoB"
                     /locus_tag="KRH82_000942"
     CDS             complement(11869..13815)
                     /gene="feoB"
                     /locus_tag="KRH82_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBG8654235.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(13833..14051)
                     /locus_tag="KRH82_000943"
     CDS             complement(13833..14051)
                     /locus_tag="KRH82_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBG8654236.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            14257..14766
                     /locus_tag="KRH82_000944"
     CDS             14257..14766
                     /locus_tag="KRH82_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBG8654237.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            14844..15005
                     /locus_tag="KRH82_000945"
     CDS             14844..15005
                     /locus_tag="KRH82_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBG8654238.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            15156..15821
                     /locus_tag="KRH82_000946"
     CDS             15156..15821
                     /locus_tag="KRH82_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBG8654239.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            15887..17671
                     /gene="pepF"
                     /locus_tag="KRH82_000947"
     CDS             15887..17671
                     /gene="pepF"
                     /locus_tag="KRH82_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBG8654240.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KIIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            17923..18756
                     /locus_tag="KRH82_000948"
     CDS             17923..18756
                     /locus_tag="KRH82_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8654241.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCGSNSGDSGDSSKVSVSGSTSI
                     GPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSAGLK
                     ETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREEGSG
                     TRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSLKIN
                     DVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFIKVN
                     Q"
     regulatory      18989..19072
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            19652..20329
                     /locus_tag="KRH82_000949"
     CDS             19652..20329
                     /locus_tag="KRH82_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654242.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     gene            20401..22416
                     /locus_tag="KRH82_000950"
     CDS             20401..22416
                     /locus_tag="KRH82_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBG8654243.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILFPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFEAYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            22466..23146
                     /locus_tag="KRH82_000951"
     CDS             22466..23146
                     /locus_tag="KRH82_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654244.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            23663..24109
                     /locus_tag="KRH82_000952"
     CDS             23663..24109
                     /locus_tag="KRH82_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654245.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            24490..25407
                     /gene="pstC"
                     /locus_tag="KRH82_000953"
     CDS             24490..25407
                     /gene="pstC"
                     /locus_tag="KRH82_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBG8654246.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            25409..26233
                     /gene="pstA"
                     /locus_tag="KRH82_000954"
     CDS             25409..26233
                     /gene="pstA"
                     /locus_tag="KRH82_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBG8654247.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            26252..27016
                     /gene="pstB"
                     /locus_tag="KRH82_000955"
     CDS             26252..27016
                     /gene="pstB"
                     /locus_tag="KRH82_000955"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBG8654248.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            27044..27697
                     /gene="phoU"
                     /locus_tag="KRH82_000956"
     CDS             27044..27697
                     /gene="phoU"
                     /locus_tag="KRH82_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBG8654249.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            27855..28724
                     /locus_tag="KRH82_000957"
     CDS             27855..28724
                     /locus_tag="KRH82_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBG8654250.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            28811..30247
                     /locus_tag="KRH82_000958"
     CDS             28811..30247
                     /locus_tag="KRH82_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBG8654251.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            30295..31122
                     /locus_tag="KRH82_000959"
     CDS             30295..31122
                     /locus_tag="KRH82_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8654252.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(31269..31880)
                     /locus_tag="KRH82_000960"
     CDS             complement(31269..31880)
                     /locus_tag="KRH82_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8654253.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(31972..32961)
                     /locus_tag="KRH82_000961"
     CDS             complement(31972..32961)
                     /locus_tag="KRH82_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBG8654254.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(33028..33891)
                     /locus_tag="KRH82_000962"
     CDS             complement(33028..33891)
                     /locus_tag="KRH82_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBG8654255.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(33997..34593)
                     /locus_tag="KRH82_000963"
     CDS             complement(33997..34593)
                     /locus_tag="KRH82_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBG8654256.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAM
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(34633..35436)
                     /locus_tag="KRH82_000964"
     CDS             complement(34633..35436)
                     /locus_tag="KRH82_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBG8654257.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(35472..35912)
                     /locus_tag="KRH82_000965"
     CDS             complement(35472..35912)
                     /locus_tag="KRH82_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBG8654258.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(35925..38027)
                     /locus_tag="KRH82_000966"
     CDS             complement(35925..38027)
                     /locus_tag="KRH82_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBG8654259.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEDNEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(38240..39943)
                     /locus_tag="KRH82_000967"
     CDS             complement(38240..39943)
                     /locus_tag="KRH82_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBG8654260.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(39969..40928)
                     /locus_tag="KRH82_000968"
     CDS             complement(39969..40928)
                     /locus_tag="KRH82_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8654261.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(41064..41582)
                     /locus_tag="KRH82_000969"
     CDS             complement(41064..41582)
                     /locus_tag="KRH82_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBG8654262.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMSLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(41625..42110)
                     /locus_tag="KRH82_000970"
     CDS             complement(41625..42110)
                     /locus_tag="KRH82_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBG8654263.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(42107..42724)
                     /locus_tag="KRH82_000971"
     CDS             complement(42107..42724)
                     /locus_tag="KRH82_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBG8654264.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(42789..43151)
                     /locus_tag="KRH82_000972"
     CDS             complement(42789..43151)
                     /locus_tag="KRH82_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBG8654265.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVNNVLK"
     gene            complement(43895..44392)
                     /locus_tag="KRH82_000973"
     CDS             complement(43895..44392)
                     /locus_tag="KRH82_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBG8654266.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFEFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(44567..45478)
                     /locus_tag="KRH82_000974"
     CDS             complement(44567..45478)
                     /locus_tag="KRH82_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBG8654267.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            46448..47299
                     /locus_tag="KRH82_000975"
     CDS             46448..47299
                     /locus_tag="KRH82_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBG8654268.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            47303..47773
                     /locus_tag="KRH82_000976"
     CDS             47303..47773
                     /locus_tag="KRH82_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654269.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            47786..49096
                     /locus_tag="KRH82_000977"
     CDS             47786..49096
                     /locus_tag="KRH82_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8654270.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            49308..50054
                     /locus_tag="KRH82_000978"
     CDS             49308..50054
                     /locus_tag="KRH82_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8654271.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     ECSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            50416..51957
                     /locus_tag="KRH82_000979"
     CDS             50416..51957
                     /locus_tag="KRH82_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBG8654272.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            51992..53098
                     /locus_tag="KRH82_000980"
     CDS             51992..53098
                     /locus_tag="KRH82_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBG8654273.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGEKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGIVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(53476..54762)
                     /locus_tag="KRH82_000981"
     CDS             complement(53476..54762)
                     /locus_tag="KRH82_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8654274.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(54885..57983)
                     /locus_tag="KRH82_000982"
     CDS             complement(54885..57983)
                     /locus_tag="KRH82_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBG8654275.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKYLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            58687..58839
                     /locus_tag="KRH82_000983"
     CDS             58687..58839
                     /locus_tag="KRH82_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654276.1"
                     /translation="MKIFSFLLFVVGICFCIAGFMGHSSAFSGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(59131..59835)
                     /locus_tag="KRH82_000984"
     CDS             complement(59131..59835)
                     /locus_tag="KRH82_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654277.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(59826..61433)
                     /locus_tag="KRH82_000985"
     CDS             complement(59826..61433)
                     /locus_tag="KRH82_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBG8654278.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(61687..62865)
                     /locus_tag="KRH82_000986"
     CDS             complement(61687..62865)
                     /locus_tag="KRH82_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654279.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(63091..63585)
                     /locus_tag="KRH82_000987"
     CDS             complement(63091..63585)
                     /locus_tag="KRH82_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBG8654280.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(63586..64347)
                     /locus_tag="KRH82_000988"
     CDS             complement(63586..64347)
                     /locus_tag="KRH82_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBG8654281.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            65049..67883
                     /locus_tag="KRH82_000989"
     CDS             65049..67883
                     /locus_tag="KRH82_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654282.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISSKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDLTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            67926..69170
                     /locus_tag="KRH82_000990"
     CDS             67926..69170
                     /locus_tag="KRH82_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBG8654283.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
BASE COUNT        25219 a         9814 c        10001 g        24704 t
ORIGIN      
        1 ttttttaata ttactaaaaa tatatagaca aaataataac aaatatagta ttatgtaatt
       61 gtagaaatgc ttttcatagg tatattctat gaagatgaat tgcataaaaa tgaaaaaatg
      121 gaatggatat tatttagggg tgaaaaatca tgaatccatt agttataaac ttacaaaaat
      181 gtagcataca tgatggacca gggataagaa gtacagtatt ttttaaaggg tgtccacttg
      241 aatgtgtttg gtgtcataat ccagagagtc aaacatatac aaaacaagtt ttgtataatg
      301 aagaaagatg ttcaaaatgt gaagcatgta taaatatatg ccctcataag gcaatttaca
      361 aaggtgaaac aaaaatatgc ttagaccaag ataagtgtga gttttgtgaa acttgcttag
      421 actattgtgt aaacaatgca agagagattg ttggtcaaga gtattctgta agagatttgg
      481 ttaaagagat agagaaggat agaattttct atgaagaatc aggtggtgga gtaactctat
      541 caggtggaga agtaatggct caagatatgg acttcatttg tggagtaata aacatgtgca
      601 aatcaaaggg aatccatgta gcaattgata catgtggcta tgcaaagtca gaaaattatg
      661 aaagagttgc taaatgtgca gatttgtttt tatatgatat taagcttatt gatgaagata
      721 agcacataaa atttacagga aaatcaaatg acttaatact gaaaaatgtt aagattttaa
      781 gtgaattagg ggctaacata aatataagaa taccattaat tgtaggagta aatgtagatg
      841 atgaaaattt agaggttaaa aaaatgatag agtttttaaa gcctttgaat atacaagcag
      901 taagtcttct tccatatcat aatattggta aacacaagta tgataaaatt tataaaaagt
      961 atgaaggaga agaactacaa agaccatcag aagaaaaatt agaggaaata aaaagactgt
     1021 ttgaagcaag taatttcaat actaagattg gagggtaata aaatgtcaag aggaactttt
     1081 gagagaacta aaaaattaag agaagaaagt attaatgcag aaccacacat atctattgaa
     1141 agagcagtac ttatgacaga agcttataaa aaatatgagg gaagtgtaga gattcctgta
     1201 cttcgtgctt tatcatttaa gcattatatt gagaatagaa ctcttagcat aaatgatgga
     1261 gaattaatag taggtgaaaa aggtgattct cctaatggag caccaacata tccagaaatt
     1321 tgttgtcata caatggaaga tttagaagta atgcacaata gagatataat aaattttagc
     1381 gtatcagaag aagctagaaa aatacataaa gaagaaataa ttcctttttg gaaaaagaga
     1441 caaacaagag ataagataat aaatgcaatg acacctgagt ggttagcagc atatgaagca
     1501 ggtatgttta cagagtttat ggaacaaaga gctccaggac atacagtttg tggagataca
     1561 atatataaaa aaggattttt agatttaaag aaagacatag aagcaagatt aaaagagcta
     1621 gattttctta atgatttaga tgcatataat aaaaaagcag atttagaagc tatggcaata
     1681 gcttgtgatg caatggttat attaggtaaa agatatgctg agaaagcaag acaaatggca
     1741 gaagaagaaa cagatgaagc taagaaaaaa gatttattac taattgctga aacttgtgat
     1801 gttgtaccag ctcacaaacc agaaacttat catcaagcta tacaaatgta ttggtttgtt
     1861 catatagggg ttactactga acttaatata tgggatgctt ttactccagg aagacttgac
     1921 caacatctaa atcctttcta tgaaagagat gtagaaaatg gaatactaga tagagataga
     1981 gcacaagaat tacttgaatg tttatgggtt aaatttaaca atcagccagc accaccaaaa
     2041 gttggtataa cattaaaaga aagtagcaca tatacagatt ttgcaaatat aaacactggt
     2101 ggaataaatc cagatggtca agatggtgtt aatgaagtta gttatataat acttgatgtt
     2161 atggatgaaa tgaaattgat acaacctagt tcaaatgttc aaataagtaa aaagactcct
     2221 caaaaattct taaagagagc ttgtgaaata tcaagaaaag gatggggtca accagcattt
     2281 tataatactg aagcaatagt tcaagagctt atggaagctg gaaaaactat agaagatgca
     2341 agacttggcg gaaccagtgg ttgtgttgaa actggatgtt ttggtaaaga agcatatgtt
     2401 ctaactggat atatgaacat tccaaaaata cttgaattaa cattaaataa tggatatgac
     2461 ccaattagta aaaaacaaat aggtattgaa actggagacc ctagaaattt ccaatcttat
     2521 gaggaactat ttgaagcatt taaaaagcaa ttacattata tgattgacat aaaaatagaa
     2581 ggaaatgctg tgatagaaaa tatatgtgca aaacacatgc cttgtccact tatgtctaca
     2641 atagttgatg attgtataga aaaaggcaag gattaccaaa gaggtggagc aagatacaac
     2701 actagatata tacaaggtgt tggtatagga actataacag atagtttaac agcaataaaa
     2761 tataatgtat ttgataagaa aaaattcgat atggatacat tgcttaaagc acttgatgct
     2821 aattttgaag gatatgaagc tatacttaat ttagtttcaa ataagactcc taaatatgga
     2881 aatgatgatg attatgctga tgaaataatg caagagatat tcaatgcata ttacaatgag
     2941 gtaactggta gaccaactgt ttgtggtgga gaatacagag tagatatgtt accaacaact
     3001 tgtcatatat actttggaga aattatggga gcaagtccaa atggtagact ttgtgcaaaa
     3061 ccagtttcag agggaatttc acctgaaaaa ggtggagata ctaatggacc tacagcagtt
     3121 ataaaatctt gtgctaagat ggaccacata aaaactggtg gaacattatt aaatcaaaga
     3181 tttgcaccat cagtagttca aggagaaaaa gggttagata atatggctaa tctagtaaga
     3241 gcatacttta atatggatgg tcatcatata caatttaatg tatttgataa aaatgtactg
     3301 ttagaggctc aaaagaatcc tcaggattat aaagacttaa tagttagagt tgcaggatat
     3361 agtgaccatt tcaataattt aagtagaaca ctacaagatg agataatagg aagaactgag
     3421 caaacattct aggtttgctt gtaaataaaa cttcttacta tataaaatcg taactgatat
     3481 aataaagtat aaatggtttg attccatttt taaaatttta gattaattat gagctaactt
     3541 tctaaatagg aagttagctc gttaagttta atgaaaaaat cgttaaattt atatttagta
     3601 aatcatacac atattagtaa gtaatacata caaaagaata atttattata gttataataa
     3661 ggttatattt tataaaaata agataatttt aagcagttaa aataaagtca atttagctac
     3721 tttaaaataa aactaataga aaaaaggaga tttgatatga aaactttagg atttattggt
     3781 tcagggaata tgggaagtgc aatgataggt ggcatagtac agtcaggatt agtaaaggca
     3841 gaagatataa ctgtatcaga tttaagccaa gttgccttag ataaagtaaa agaagaattt
     3901 ggagtaaata ctacaactga ttcaaaggta gctgttacaa attctgatgt ggtaatagta
     3961 gcacttaaac ctaatatatg cgaaaaggct ttaactccac ttaaagaatt aatagatgca
     4021 aataaaataa tagtatctat agcagcaggt aaaactatag aaagtctgga aagttttata
     4081 ggttcagata aaaaaatagt aagagtaatg cctaatactc cagcccttgt tggcgaagga
     4141 atgtcagctc tttgtaaaaa tagtaatgta acagatgaag agttaaatat gattaaggct
     4201 ctgtttgaat cttttggtga ggcagaaata gtatcagaat atttaatgga tacagttaca
     4261 ggtattagtg gttcttctcc tgcatatgta tttatgttta tagaagctat ggcagatgca
     4321 gcagtattag ctggaatgcc aagacaacaa gcttataaat ttgcatctca agcagtaatg
     4381 gggtcagcta agatggttct tgaaactgga aaacatccag gtgaattaaa agatatggtt
     4441 tgttctccag caggaactac tatagaagct gttaaggtat tagaagaaga aggctttaga
     4501 gcagcagtta taaaatctat tgttgcttgt atagataagt ctaaagatat gagcaaataa
     4561 cagatgtaat taagtttact atatggtttc ttgaattgtt tttttagtgc ttatttatat
     4621 ctatacataa atgtatttgg tataagtaaa ataagagtaa tttactataa aaaggaattt
     4681 aatgattgag tgagaattta ttacttaaat attaataatt aaatagatat atttttaact
     4741 atatttgaga tatatcattg tgaaaaaata aaatttataa gtattattgt gaggttataa
     4801 gtagatttat ttaaaaataa atttatttat agccttttta aatttgaaat aatattcata
     4861 aggtaataaa agttacaaat attttcttcg ctaataagtt ttaaaatacc tataatgttt
     4921 tactttttat tataataaat acaataaata tattcttata taaattctat gtcagatata
     4981 tggaaagata agaaccttga gattatgtta aaaaatctag attttatact tataaaaagt
     5041 ttgattttac aaccttacaa aagagaatca agataggaat ataattatct ttttcataaa
     5101 tatataaatg atatactaat attatagtat tattgatatt tgtattggag gttgaacatg
     5161 agggatgaaa ttttaagttt tgtaaatgaa tgtgtattat ttaacaactt tgatgaactt
     5221 aaaaaagaaa gtggcataat aacagaagat atagtaaaaa agtttaattt aagtagaact
     5281 caatcaagta gattattaaa tgatttagta aaatctgata atcttataaa gataaacagt
     5341 agacctgtta tttttttacc taaaaataaa ataaatgatg tagtaggacc tacaaaaaaa
     5401 agtatttatg aaaatttaga tgaacttaaa aatgagtgta aattattaaa gcaagagact
     5461 gtgtttaata gtatcatagg atatgagaat agcttaaaag aagtaatcga acaaataaaa
     5521 accgctgtac tttatccaaa tggcggactt acaataatgc tgacaggtga aagtggagta
     5581 ggaaaaactt ttttagccaa gataatatac aaatatagtg taagcagtaa tgtattagaa
     5641 aaaaattctc catacaatgt gttaaactgt gcgcagtatt ataataattt ggagttattg
     5701 tctagtctat tatttgggca tgtaaaagga gcatatactg gagcaaatga atctagagca
     5761 ggtctaatag aacaatcaga tggtggtgtt ttatttttag atgaagtaca tagattaaat
     5821 agtgaaggtc aggaaaagtt atttacattt atggatacag gtacgttttc taggattgga
     5881 gagaatggag taattagaaa agctagggta agattaatat ttgctacaac agaaagtcta
     5941 tctgaatttt tacaaacctt tttaagaaga atacccataa atatttatgt tcccaatata
     6001 gaagaaagag ggactattga aaaaagaaag attgtagaac attttattta tgaagaaagt
     6061 aaggtacttg gtttgcctat agagataact caaattacat taaatgcgat tttaaagata
     6121 aaattcaagg ggaatatagg tgaatgtaaa aatgtaataa aatatgcatg tggacgagct
     6181 tatgcaaaaa atcaaagaag aaatggaaat atttttgtta ctcttcaaga ccttcctaga
     6241 aatctttata tagaaaatgt agatatattt caattccaaa gtggtaaaag caaaagcatt
     6301 atcttttctc ctaaacaatt tagtattgaa atgtcaaatg gaagaaataa aagaaatata
     6361 atctatcaaa gtttcataaa atgtttagat tactttgata gactagaaaa aaatgaaata
     6421 acaaaggaaa aatttagtaa aaagagttct aatctaatga ttagactaat ggacaattta
     6481 gtcttttcaa ataatgatga aaataataac gtacttatgg agcttataat atcgataatg
     6541 caggatatat ttagaaattt agaagttaat aacaatataa aatatgatgg gaataatgta
     6601 ttggcatttt cgtcttatct ttatttgaag gacgaatctt atcaattgtc tgatgagtat
     6661 aaagctttag aaaataaatt actaatatat ttaaaaaaag agagttacaa agaatactct
     6721 ataataagta aaatatcaac attaataacg aatagattgg atatgtatct taataatgta
     6781 gatacaatca taatgattat atttattaaa tcaacaatta taagaatgaa atttaatcaa
     6841 gttaatgcga ctattatagc acatggatat gctactgcca gtagtatggc gaatgtatgt
     6901 aatcggatgt tgggtaaaaa tatatttaca gctattgata tgcctataga tgctactatt
     6961 gctgatgtat caaaacaaat gtctagatac ctagagggag ataggataaa gaatggttta
     7021 attgtgttat ttgatatggg ctctcttaat cttatatatg aagatttaaa gaataagata
     7081 aatagcccaa tgttatttat agaccaaata tccactattt ctgcactaga agtaggaaat
     7141 ttattaatgc aaggtaaaaa cattgaagag attgcagaaa ttatggatga agaaactaaa
     7201 cctaatatac aattgtatta tcctcaaaaa aataaagaat atgctataat atcatcttgt
     7261 tttacaggga taggtactgc tataaaaatc caacatctac tttccgaaag tttaattgga
     7321 atagttgatg tcaaaataat accttatgat tatgatagtc ttgtttctat gggagataaa
     7381 gaaccagttt ttgaaatgta tgatgtgatg gctatagtag gaactgccaa tccaaatgtg
     7441 aatggggtag attttatatt attagaggat ataatatcag gaaaaggaga agatgatgtt
     7501 tttagaatat ttagcagagt agtagaaaat gaaaaaataa agaacataaa tgattctatt
     7561 gtaaagaatt tttcattaat tagagtaata gatagtctaa ctattttaga ttcaaaaaag
     7621 ataatagaga gaatagaaga aggaattaat gctatagaaa atattcaaaa gaaaaaactt
     7681 tcaaatgata aaaagatttc tttatatgtt cacttaagtt gtatgattga aagattagtt
     7741 agacaaactg aaattgaaga gtatactgat atggatttgt taatcaaaaa ccatcatagt
     7801 gaagtaaaac taataaaaaa tgcatttagt gtgctagaaa agagttatag tgtgcaaata
     7861 ccaatttcag agataggata tatttataat attatctatg gtctaccaca gtaaaataca
     7921 agattacaaa ataagtgaat gaaatttaaa aaagtatgcc agtatttggc atactttttg
     7981 cttttataga taaatgagag tataaacaat aaaaatttta atgtatgatg gaggatttgg
     8041 ggaaaatggt atctttgatg agaattgatg acagattgat acatggtcag gttgcatatg
     8101 gatgggcaac atcactaggt ataaatgtaa tactagttgc aaatgatgaa gcaaaaaatg
     8161 accaaatgaa agctatgtca ctgaacttag cgaaacctag caatgtaact ttatatataa
     8221 ggggggtaga ggaatctgga gaaatagtag aaaaatttgc ttcttcaaag aaaagcaatg
     8281 tattagtgtt agtaaaaaat accaaagatg ctttagttgt agctaaaaat tcaggaggag
     8341 tattaaaaga aataaatgta ggaggattaa gatatgagga agggaagaag aaacttacag
     8401 atttagttgc tgttgatgat gatgatataa ataactttaa acaaataggt gatttaggga
     8461 ttgatataga atttagaatg ttacctagag acaaaaagaa acaactatca gatttaataa
     8521 aataatttag gagaaagaga atgaaaaaat ttctaattgc aacacatgga gaattgtcca
     8581 gagagcttgt tgacacaagt aaattaataa ttggttcatt aactaatatt gagtattttt
     8641 gtatgacaac ggataaatca gcagatgatg ctgagaaaga aattagaagt atattatcaa
     8701 ataataaaga tagtgaagaa tttgttgtct taacagatgt ttttggtgga agtgtggcaa
     8761 acatatgtac aaacttactt ttacaagggt tcaaatttga attattgaca ggagtaaatt
     8821 taccaatgct tttatctata cttttattag ttgaggagga tacaaaacta atagttaaat
     8881 caggattaga ggaagcaaaa aatggaattg tttatgtaaa tgagttatta gaaaatcaaa
     8941 acaaaatcaa aaatgtaatg taatttaatg taaattaaac taagttaaaa tggaggttca
     9001 atatgttagt acaagctact atgttagcta ttatagcagg agttggtata ctagatgggc
     9061 gtatatttgg tcaatctatg cttgataggc caatagttac aggtatgtta gtaggattag
     9121 ttttaggaga cataaaatca ggaattatga ttggtgcaca gcttgaatta atttggatgg
     9181 gaattgcagg aataggtgca gctactcctc cagatgtagt aacaggaggc gtattaggta
     9241 cagcttttgc tatattatca ggtaatggtg cagaagttgc tttagcagta gcagtaccag
     9301 tagcagtctt agcacaatct cttggagtat tagttagaat aataaattcg tacttttctc
     9361 aaaaggcagt tttctatgct aaacaagctg attttaagaa agttaccata atgatgtggt
     9421 tgccagtaat attattcttt ttaagtacat cagttccaac ctttttagca attatgattg
     9481 gtgctgataa agttacagca ttgataaatg caatacctaa agttatatta gacggactgg
     9541 gtgttgcagg aacattgttg ccagcagtag gttttgcatt gcttatggat atgttacttt
     9601 caaaaaagat gtctgtattt ttctttatag ggtttttgtt agcatcttat ggtggattag
     9661 atataactgc tatagcttta tttggagtat gtgtagcatt tgtactaaac ttttatatca
     9721 ataacaaaga aaataatcaa aatcctcaat tagcaatcaa tactttaacg gaaggagaga
     9781 ttgactttga ataaattaac aaaaaaagaa ttaagaagta tgttttggcg ttcatttgct
     9841 cttcaaggtg catttaatta cgaaagaatg caaaacttag gttactgtta ttcaatgtta
     9901 cctgcaataa agaagctata caataagaaa gaaaatcaag caaaagcaat agaaaggcat
     9961 ttggagattt ttaatacaac gacagtagta gttcctgcta tattaggtat aacagcagct
    10021 atggaagaag agaatgctaa taatccagaa tttgatgaaa gttcaattag tgctgttaaa
    10081 acagctctta tgggacctct tgcaggaatt ggtgattcat tattctgggg aacatttagg
    10141 attatagcag caggagtagg agtatcactt gcaaaagaag gtaatatctt tggaccacta
    10201 ttattcttac tattatacaa tataccagca tttgccctta gaatatttgg acttaagtat
    10261 ggttatcaag taggggtaaa ttctcttgaa agaatacaaa gagagggact tatggagaaa
    10321 ataatgtcta tggctacaac tgttggttta ttcgttgtag gaggaatggt tgcaactatg
    10381 ttgagtataa ctactcctct gaaattcaac ttaaatggtg cagaagtaat tttacaagat
    10441 atactagata aaataatacc taatatgtta cctttaacct ttgcatttgt aatatactac
    10501 atgttaaaga gaaaggtaag tgtaacaaaa ttaactatag gcactatagt aacaggaatc
    10561 gctttacatg ctataggttt gttatagaaa ttaattataa tttattgaat atatagataa
    10621 ggaaggtgta taaaatgaca atacaagatt atatgttaga aacaccagtt agaatgagag
    10681 aaattatatc taatgcagat agcttattta atgaagttaa gagaacaaat ctaaaaaaga
    10741 ttataataac aggttcaggt actagctatc actcaggagt gcaagtgcaa ccatatttac
    10801 aaaatttatt agatatagat gttgtgaaaa tgtatccatt tatgataact gaagatacat
    10861 tcaagtttga taatgaaaat accctagtag taggtgtatc tcaaggtggg agtagttatt
    10921 ctacatacaa cgctatgaag ttagctgaag ataagggctg taaaatagca tctatggcag
    10981 gttgtaagaa tgctttaata gatgagattt ctgattatat attaacagta aattgtggtg
    11041 aagaaaaatc tggagctaaa acaaaaggat attattgtac aaagttaaac ttaatgttat
    11101 taggtcttca aatagctaga gaaaaaggta taatatctag tgaaaagtac aatgaggaaa
    11161 taaataagat attagacgca attaatagat ttgaagcagt gtataagctc tctaaacaat
    11221 ggattgaaag aaacaaagaa aagttagtta attctaaaga aataagaata ataggtcact
    11281 ctgatatata tggagataca ttagaagcag cattaaaatt attggaaaca atgagaatac
    11341 ctgtaactgg gtatgagttt gaagagttta tacatggtat atataatgct ataaatagtg
    11401 attctactat atttatacta gatacaggaa aagaacctag agtaactaag atgattgatg
    11461 tactttctgg ttggacggaa aatgtatttg ctataggtag agatgttaca gaaaatgata
    11521 aaaatttaaa gattgatatc acagataatc cttactatca aacatttaat tttatagtac
    11581 ctatacaact aatatgtggg gaaataccta cattaagagg tgtagaccca agtgttccaa
    11641 aagatactag gttccacatg aagttaggta gcaagaaact gaataagtaa caaaaaaaga
    11701 ggttgtctca aaatagagat aagcctcttt tttactagat aagctctttt ttactgttga
    11761 aatgatgaaa atatatttga ttttctataa aaaagagtgc ctcatgaact aaaaagttaa
    11821 ttttgagaca cccactttta tcttatttta aactaaaata tttatatatt agtgtgcatt
    11881 atttttttta ttgctgtctt ccttacttga gcaagaatta gcacttggac atccagaaca
    11941 aatagaacat ccactacaga catttccgtt ttttgtagac ttgaatttat taaacagaat
    12001 aaagagtgca aggactataa ttattccacc tatcaaagct tctattattg aattacccat
    12061 aaatagtact ccacctatac ttttaactat aaaagccatt atccatgcta gtataaattg
    12121 atatgcaaat gatgtaaaca tcattttatt gccatattct tttttcatag ttgcaagtgc
    12181 agctatacat ggagtatata aagcagtaaa tatcaagaat gtatatgcag taactccatt
    12241 aaatattgtt ggtaagacaa cagttagatt accatatagt atatttaaag agtttactac
    12301 gatttctttt gctccaagac cacttaaaat agcaactgaa gttctccaat catcaaaacc
    12361 aagaggtttg aatataggag atataatatg acctagagta gccaagaagc ttacatttat
    12421 atcttctgta tatccaaaaa cattgaatga agaaagtccc caaattacga ctgacattgc
    12481 aaacatgaca gtaacaactc ttatcaagaa accttttgat ttattccaag tatttttaat
    12541 aagtgcatct atagtaggga ttctatattc tggtaattct aatataaatg gttcagcctc
    12601 tgttttaaag gctgttttat ttaagaataa tgcaactaca attgccataa ctatacccac
    12661 caaatacagt gatgtagtta ctaaagcagc attatgtgga aagaatatag ctacaaatag
    12721 tgcatatata ggtagctttg ctccacaagt cataagtggt gcaataagag ctgtaactct
    12781 tctatctttt tcgctttcca atgttctagt tgccattata gctggagaag aacatcccat
    12841 acccataact ataggtataa aagctttacc agatagacca acctttctca taactttatc
    12901 cattaaaaat gctgttcttg acatatatcc actatcttca aacaacgata taccaaagaa
    12961 taatgtaaat attaaaggga agaatggtaa agtaccacca acacctccaa ttattccatc
    13021 aactataagt gatttaaacc atgggctaga gttagataac atatcactaa caggtgcaga
    13081 aatataagcc tctataagac tagcaaatcc ctcttgtagt ggacctccga cccagtcaaa
    13141 ggtaaattta aataagagga acaatacacc aataaatatc ggatatgcta atataggatt
    13201 caagactata ttgtctatct tatcactgat agatttcttt tgtgtatatg tagtttttgt
    13261 acatcttgat aaaatggatt ctaatttttt atatgtttct gtttcacttc caaagttttt
    13321 ctgatatata aaagcttttt gcgtagctcc cttaatctct tcttctatcc tatcaacacc
    13381 atttttcttt tttgctataa ttggaacaac aattactcca agttcttcac ttaatttttt
    13441 ggcatctata ttaactcctt tagattctgc aatgtctaac atattaagca atataactat
    13501 aggcttgtta aattgcataa gttgagttgt taagtaaagg tttcttgata aattagaagc
    13561 atcaactaca tttactatta catcaacatc ttcattttct aaatatgatt tagaaacctt
    13621 ttcttcattt gagaaagtat ccattgcata tataccaggt aaatcgacaa cctttatctc
    13681 ttttccaaga aatccttctt ttttttctat agtaacacca ggccagttac ctacatattg
    13741 atttgaacct gtaagtagat taaaaacagt agttttaccg acatttgggt ttcctaataa
    13801 tgctacatta atcacgggta gctcctcctc tattattgta aagaaatatt tttagcatca
    13861 gattttctaa tcgcaaggtc aaagcctcta aatctaatta taattgggtc tccaagtggg
    13921 gcaacctttt taacttctat ttcagtacta tttatacatc caagtgcaag caatctttta
    13981 gataatttaa tatctccatc tatactatta ataaatcctt tttctcctat ttttaaatcg
    14041 taaacagtca ttattaacac ctcctaatga aattcattat cattaaaatt gtaacaagta
    14101 tgatacaaaa agtcaagatt tatagaggta attgcacatt gaaataacta atatttattc
    14161 taaatagatt aaaaatattt tagtctaaat taggtgtttt tatatatttt gtattataat
    14221 gtaagatgat agataaaatt tggaggagtt aacttaatga aaactagaaa aatgacattt
    14281 ttaggtctta tgatagggta tagtttagct ttatatgtat tagagacata tataccaaat
    14341 cctcttatag ttatatttcc aggggcaaaa ttgggtttga gcaatattat aactttaatt
    14401 tcattaatgt tgttaggtgt caaagatact gttataattg ttactatcag ggtaattttg
    14461 tcatcaatat ttgcaggccc tttatcatat ctactattta gtataggagg agcttatctg
    14521 agtcttttat ttatgtattt agcgagtaaa ataaaagatt tatcactaat agggataagc
    14581 attataggtg caatagggca taatataggt caattaatag ttgcaagttt aatcatagaa
    14641 aatatacttg ctatagggta cttaccattt atgttaatgg catcattagt aactggtatg
    14701 tttgtaggct tagtatccag gtatacaata cctaaattaa agcattttta tagtaagttt
    14761 tattgacata atattgacaa aatataatat tgtttgataa aatgtatata aaaatataca
    14821 aatttgtaat agtggtgatt attatggcga acaatgaatt agaagcgtta aaaaatgaga
    14881 ttgaagcagt tagggaagag ataaatacat acatagaata tccagaaata tttcaagaag
    14941 agttagtaga atcaagtaag aaaatagata tattaataaa taaatacatg tacctaagca
    15001 aatagcccac agttgtgggt ttttttgtat caaaaattaa cagatggcta tattttacat
    15061 atattaataa taatattaag atataaaata gtatttctga tgtgtaaatt atctgtagga
    15121 cataagttgt aattaagtca ggagggtttt atattatgat tgatatagga agtaaggaga
    15181 tagcaataag gttactatta gcactaataa taggaggaat aataggctta gagagagaaa
    15241 aaataagaca gtttgcagga tttaggacac atatactaat tgcaataggt tcttgtattg
    15301 tttcaataac ttcgattcaa ttattctttg attataattt gtatacaaat gctgacccag
    15361 caagaatgcc tgctcaagta ttatctggaa ttggtttttt aggtgcagga gcaattttaa
    15421 aaaataaagg tggagtaaaa gggcttacta cagctgctgg gatgtgggca actgcatgta
    15481 ttggtatagc agttggatat ggttattatg aattggcaat tctaggtgga ttatttgtaa
    15541 tgatagcatt atttgtgctt aggataatca atacgttttt atttagccaa gaaaagaatg
    15601 tgttgatatt aaaattaagc aatttggact ctataccttt tttatatgat aaatttgaaa
    15661 aaaatcaact tatcgtaaga aatatggaaa tagaatgtcg taatgaagaa tactggaagg
    15721 ttaatttttt tgtatcttat gctaagagaa tacacttaca cgacgttatg aaagaaataa
    15781 atatgataga aggagtaata aatgtagatt atttggacta aaatatatac aatatatttt
    15841 gtaaagtgaa taaaatataa aacaaattaa aatagaggtg tatgatatgg gaactgatag
    15901 aagtacaata gaagaaaagt acaaatggaa gatagataag atgtactcca gtaaagagga
    15961 aattgaaaaa gacataagta aagtaaaaaa tcttatccaa gaagtaaaag aatataaagg
    16021 gaagctttct gagagtaagg agaacttata taaagtatta aatatctctg aaaatgcatc
    16081 taggattgtt caaaatttat atgtatatac tcatatgaaa caacatgaag atactagaat
    16141 taatgataat caaggaagag ccactaagac agaaatgtta tctactgatt taggtgtggc
    16201 tacttcttat atagttccag aaatactggc gatagaagag aataagttaa gtgaatactt
    16261 aaaagatgag aagctatcct tttatgcaaa atatataaag gatatattga gagataaacc
    16321 acatactttg agtgaacgag aggaagaaat acttgcagct acatcagaat tatcgacaat
    16381 tccagaaaat gtatacgata tgttagcata tgcagatatg gaatttcctg agatagaaga
    16441 tgaggagggg aataaggtta agctttctca ttcaaactac tctttattta taaaaagtaa
    16501 gaatagtaga gttagaaaag acgcttttga aggtgaattt tcaacatatg agaaatataa
    16561 aaatacattt gcctcaacgc tttatggtgg aataaaatca gagatatttt acgcaaaaac
    16621 tagaaagtat aattcagcaa tagaagcgtc tttattttca gatgatgtaa gtttagatgt
    16681 ttacaataat cttatatcag ctatagataa aagtattcct aatctaaata aatatgttga
    16741 gcttaaaaag aaatttttag gattgaatga aatacacatg tatgatttgt atgttccttt
    16801 gacagataaa tttgacatgg atataccata tgataaagca caggatatca tattagaggc
    16861 acttaaacct ttaggagaag aatacttgaa gatcataaaa agtgcttttg atgaagggtg
    16921 gattgatgta tatgataatg aaggtaaaaa aggaggagct tattcttggg gaagttatga
    16981 ttcacatcct tatatattaa tgagctataa aaatgacctt aattctctat tcactttaat
    17041 tcatgaatta gggcactctg ttcacagtca ttattcaaga acaagtcaac catttttata
    17101 ttcggactat aagatattcg ttgcagaagt tgcatctaca ttaaatgaat tacttcttat
    17161 aaattattta ttagaaaatt ctaagtctaa ggatgaaact atatacttat taaattatta
    17221 tttagaacaa tttagaacta cagttcatag acaaactatg tttgctgaat ttgaaaaaat
    17281 tgtacatcaa agggtagaga gtggagaacc acttactgct gatgaattta ctaatatata
    17341 ctacaaatta aatgaaaagt attatggaaa atctgcaata gtagataaac aaataggaat
    17401 agaatgggcg agaatacctc atttttattc aaacttctat gtatataagt atgccacagg
    17461 gttttctgct gcaagtgctt taagtcaaca gatactttca gaaggaagta ctgcagtaga
    17521 tagatatata aacttcttaa aaagtggagg gtcagaatac ccactagaac aattaaaatc
    17581 tgctggtgta gatatgacga aaaaagaatc tatagaggaa gccttaaatg tatttgctga
    17641 attagttaat aaactagaaa aagaattata ggatgtgata ggttgatagc ttcaatgaag
    17701 acttctgata atatgagttg tattatgttt atatctgcct aaagtaactt taaaaagtta
    17761 atctaattaa gaataaatca tataaaatta agtttttaca tgtatttaac aatatttaca
    17821 tttacttaac cctgctctaa tattcattta acaaagaatc tgtattatta aaatatagaa
    17881 aaatgacaac aaaaaattaa aatataagcg ggggtaagta aaatgtttaa aaagaaaata
    17941 ggcgttcttt tagctagtac aatgttagtt ggagctttag cagtaggatg tggctctaac
    18001 tcaggagatt caggagattc aagcaaagtt tctgtttcag gttcaacttc aataggtcct
    18061 cttatggaaa ctatcggaga aaagtttcaa gaaaaaaatc aaggtgttag tgtagaagta
    18121 caacagattg gttcttctgg aggtataaaa aatgctatag aaggaacatc tgaaatagga
    18181 atgagttcaa gagatttaaa agatgaagaa aaaagtgctg gattaaagga aactaaaata
    18241 gcaatagatg gtatagcatt gataactaat actgcaaact cagtaaaaaa tctgacaatg
    18301 gaccaagtta aaggtatata tacaggaaag attactaact ggaaagaagt aggaggaaat
    18361 gatgcaccaa tagtaatagt atcaagagaa gaaggttcag gaactagaga tggattccaa
    18421 gaaattgtag ggtttgattc agaagaacta actaaagatg cacaaataag tgatggttca
    18481 ggaaatataa aaactacagt tgaaggaaat gaaaatgcta taggatatat atcatttgga
    18541 tatgttgatg agaaagtaaa tagtttaaaa ataaatgatg ttgaagcaac tgatgcaaat
    18601 gtaatagcta ataaatatcc aatatcaaga ccatttatat tagttaataa agaagatggt
    18661 ttgtcagaaa aaggtaaagc tttaatagat tatatattaa gtgatgaagg acaagcactt
    18721 gtttcagaaa aaggatttat taaagttaat caataacaag agttataata taaagtaaac
    18781 atataatacc ctgtgagata agctcataaa aatgatgctt taacttgcag ggtattgtct
    18841 attattgaat gtagaaatat aaatatcttt agataaaata ggtattttag tatcttatct
    18901 ctaagaatat ggaaatattg acaaaataat attacaatgt tagaataaaa aagaaattta
    18961 tgaaaatata taaaagattt ttaataaaaa tattttagaa actgagaagt atatcttatt
    19021 attgggcatc tagagatata tggagttagt ggtgcaaccg gctatgaata taatttttat
    19081 attgcatagt ctttttttgt tttaaaatta acaaatatgt tgcaaaattt gaaaatagga
    19141 gtattagtcg ttaagatttt tattgatagg taaaattttg gcttttaaag tagccatttg
    19201 ttggaaaagg gaaatttttt taaaagaata atagtattat aataagaaaa taaagttttt
    19261 ataaacattg agatgcagaa tataaacctt ttgtaacaat atatttacca aaataataca
    19321 atttatttta tattataacc atataaatca tataaatcaa tactcaaact agccaataga
    19381 caagtttcta gaaaaataat aaatttatac gtgaaaatga ctttaagctc cattctccaa
    19441 caatcggaga ctttaattag tatttaataa tgaatcttaa tgtttaatac aatattcaag
    19501 aattattcaa aaatacttaa gtattatagt ctagtttgta aagatattat aaaataataa
    19561 taccagttat atatgaaaat aaaacattat aatttgtaat aactataaaa cttggaatta
    19621 taattaaaat acctttgaat ggagtggtgt aatgtataat ttactggttg tagatgatga
    19681 tgttgatatt ttaaacataa atcaaattta tttttctaat ataggtttta atgtatatac
    19741 atcagagact gctaaagatg ctatggatat agtagagagt atagttttag actgtataat
    19801 tttggatatt tcattgccag atatagatgg atataaaatg tgcaatgata taaaagaaaa
    19861 ggttaacata cctataatat ttttatctaa ttatgagcat gaagaagaaa aagttcgggg
    19921 atttttagct gggggggatg attatataac aaaaccctat agtttaaaag aacttgaact
    19981 tagaatatat gctcgtatga ggcagtacaa aaatattaca tcagttccta atgtgttaaa
    20041 gttttcagcg ttagtaataa atgtaaattc aagaaaagta acttttgatg gagaaagtat
    20101 agatttaact actatggaat ttgaaatatt attgtttcta gctgaaaaca aagaacaagt
    20161 attttcgaag atagagatat ataaccaagt ttggaaaatg cctgatattg gagatcaaca
    20221 tacagtgcag gttcatattg cacagatgag aaaaaaaatt aattctttaa gcagggagca
    20281 tcaatacatt caaaccgtat ggggaaaagg atataagttt gtaccataag tgagatactg
    20341 taattaataa atagttcttg ttttatttaa tactactatg aaagagatgt ggttgataca
    20401 atgaaaaagt ataatatact aaaaggaact ctcattgtat tgatagtctc tctgttggca
    20461 ataacaggat taaatcttct gtataaatat gataataaat atacatataa gtctattaga
    20521 gcaagtaatg gaattttaac tatagataat gatactttca ctaaaggtaa acttgtcttt
    20581 ttgatagatg actgggagtt ttataatcat aaaatattta aaccgaatga ttttacagag
    20641 caagatataa aaccagaata tgtttttata ggtcaatatc cagatttttc tatgagaaag
    20701 gggactcagt caccatatgg gaatgctact tatcgtatga gaataaaaaa tgaaggcaag
    20761 gataagctac taagtttaga gcttcctgag attttttccg caagtgaagt atggataaat
    20821 ggagaaatgg tttctaaatt aggagatgta ggaacagaaa aatatagacc caaaattaaa
    20881 aattcagtag taagttttat tgcaaagaaa aatacagaaa ttataatcaa tgtatcgaat
    20941 ttttcacatt attatagtgg tttgtattat ccgcctgcat taggagaaac aaaggacata
    21001 agtaatatga tgttttatcg attacttttt tatagtataa tttgcttcac aacttttgca
    21061 atagctatat tttcattgtc tgtatggttt ctttcaaaca aaagtaaaat ttacttatat
    21121 tttggatgta tgtgtgtttt ctttgccatc catgtatcct atccctttgt acatttgtta
    21181 ggactgcctt tggtaagctt tacatatgcg gttgaagatt tgtcatattt tatggtagtt
    21241 ttatgtatta tttgtataaa tggaagtata tccaaaatag aagaaaataa agtgtacaga
    21301 tttttaattt taccattagg aattacaatg agtatcatat ctatagtgat accaattatt
    21361 ctttttccat atgatatgta ctttgtcaac atatatggga agttaataga catatataaa
    21421 tatattgtat ttatatatat attaatgtct tcgctggttt caatatataa aaagacatgc
    21481 tctgagcata taagttctta tattttagtt tcagtaaaca ctgtttttgg aattagcata
    21541 ttatttgatg cagttacgag taatagattt gagcctatat ttacagggtg gcaaacagaa
    21601 tattgtgggt ttgtaattgt tattttattt tctgttatga tgataaacag gaatagaata
    21661 ataataaaag agaatgaaaa acttacaagg aatcttgaac atgaagttga agtgagaact
    21721 aatgaactta caacattgtt aaatgaacgt aaaagattct tggcagatgt agcacatgat
    21781 ttaaaggcac ctgtttcggc tatacaagca tttatagatt tgataaaggt tggtaatatt
    21841 catgtagatg aagagacaag aacctatctt tatgctataa atcaaaagtc aaatgaagta
    21901 caaaatagag tacgtagttt gcaagaattt acatcacaag ataaaagcat tggtattagt
    21961 gaaaaaatat gtctgaataa ttttattaaa gagatatatg aaaataattt gccagataca
    22021 caagcatgtg gtgtaaactt tgaagcttac gtattggaga aaaaaatata tgcaaagata
    22081 aataaagaga tgcttacaag agcatttgag aatttaattt ataatgcttt gacctttact
    22141 ccatttgatg gaaagataat tttatcaatg gataaagaag atggatttgc aattattaaa
    22201 atttctgata atggaaaagg tatacctcca gaaaatatac caaaggtatt tgacagattc
    22261 tttacagaaa gagacaataa tgagccaaaa gggcaagggt tagggctata tattgtcaaa
    22321 tccattataa gagagcatgg tggagaaatc tttgtagatt cagaactagg aaaaggaact
    22381 gtttttacaa taaaattaag tctatgtttt ttataataat agcttattta atataaaaga
    22441 ataatgatat ttgggagtga ttataatgca aactaagata ttgataatag atggagacaa
    22501 ggataattgc cagaagctaa aaggatttct ggaggaaaaa ggaataagta tagatttagc
    22561 atataattgt gaagaagcta ttggaaaaat atttagcaat aaatatgatt taatattttt
    22621 agaaataatt ctaagtgatg gtgatggatg gactctttgt aaaaaaatta gaaatgtaac
    22681 tacttgtcca attgtttata tgacttatat aaatgaagac caaagcattt taaatgcttt
    22741 aaattctggt ggagacgatt acttaataaa gcctctaaat ttagaaatat tatacgcaaa
    22801 agtaaaagct attttaagaa gaatgaactc atatgtaaat aataatgaaa ataatacaaa
    22861 attagaggaa tataatagaa ctagtggagt aataaagtta gaagataaaa taataaaatt
    22921 gactccaaca gaaaataagt tgttaaactt ttttatagag aatcctgaaa agactttgac
    22981 tactaaagag atatatgaac atgtatggat gaatgaatac ttagaggata actatagtgt
    23041 ggtagttgca gtgaatggat taagaaagaa aatagagaaa gattataaaa atcctcagaa
    23101 aattataaca ataagaggag caggatatta ttttaataaa gaataataaa tatattaata
    23161 tcattaataa ttgttataaa tgtgaaatac taacgatatc taaactaaat tattataaaa
    23221 tagctgactg taatttaatt gataaagcct attcttctag actttgccaa ttaaattaca
    23281 gtcagtttta ttatataaaa aaatgcgtaa cagaactatt attttataga ttatatttga
    23341 aaagataaat aaattgtata tctaaatcta tatattattt tttaccttta atatatatta
    23401 aataataaaa tagttaaata ataagattaa gaatttctta ataaatccag aagatgcttt
    23461 cgattatata atattttata tttttatatt attaattata tgtgttgcaa ttgctgcacc
    23521 tactttttct ggtgagtatc agacacaatc agatagcatc cttcgttgta cgaaacatgg
    23581 acatattcgt ctagcgttta ctaaaatatt agctctattt tctatattta taataatgtt
    23641 tgttatatgt atttctatcc atttggcaat ttctgattta gcttttggta ctgaatgttt
    23701 gaaaacctca tttcaaatgt tgttttctgt aattagtcta gtaaatataa atttactaca
    23761 agcacagatt cttatagcta ttggtggtct aatttcaata cttgcaatgg ttagtttaac
    23821 attattttta tctgcaaaat gtaaggattc tcttacttct atgctgattg ctttttctat
    23881 ttgcttaatt cctatgggaa taggtgttag ttggattgga tacctattac caccaggggg
    23941 aattggtttt aagattagtt tattatatca aatgacatca tttaatttct tacacttagg
    24001 aggtatgagt ttttggacac cacacattat actgtttttc tcagtgatag aaatacctat
    24061 ttttatattt ttggctattc gtacctattg caaacatcaa gtatcgtaac aatttgatgg
    24121 aaataatagt gatataaact agaggataca ataattatat atgtagtata aaagttaaat
    24181 ttagttaaca aatcttaata gcagatatag gtaataaatt atacataaac tgtattatta
    24241 tctatatctg ctattttaat atagagaaac aacagtatat tgtaaagtaa atgtcaaata
    24301 tagttttaaa agtaaaatta atgttaaaaa gtaaatataa ttttacactt gcttaactta
    24361 atcctaatat agatttaact taaaaaaagt agaataaaag tataggaaat ttgatgaaga
    24421 cgaattataa aaaattaaat tttgaataca gaacgaaaat cgataagtat attttaatgg
    24481 gagggtatta tgatagtaaa atctagatta gtaggtttag aaaaaaatga caataatggc
    24541 aataagacaa aatacgtaat tgaaaaagta gcaaaaaata tttttctact tagtgcttta
    24601 gtagcagttg caagtttact tttgataata ggattcgtat tttataaagg attaagacca
    24661 tttatatttg aaggatattc atttatagac tttttaactg gtgcagattg ggttccttct
    24721 gccaataaat ttggaatatc atctatgata gtagcatcaa tatttgcaac acttggagca
    24781 cttgtgatag gagtacctgt tggtatatta acctctgtat ttatagcaga agtagcacct
    24841 aaaagattag caaaaataat gtcaccagca gttgaacttt tagcaggtat accttcagta
    24901 ttatatggtg tatttggtct tgcagtgata gttccaacta tacaaagtat atttaatctt
    24961 ccaaaaggtc aaagtttgtt agcaatagta atagtattag cagtaatgat gttaccaaca
    25021 ataatatctg tatcagaaac agcaataaga gcagtaccaa aagcatacaa agaaggttca
    25081 ttagcacttg gtgcatcaaa aatagaaaca atattcaaag ttgtattacc tgctgcaaaa
    25141 tctggagtat tagccgcagt agtgttagga gtaggaagag ctttaggtga aacaatggca
    25201 gtaatacttg ttgcaggcaa ctcaccagtt atgccaactg caataacaga tagtgtaaga
    25261 ccacttacaa ctaatatagc acttgaaatg ggatacgcat ttggtacaca tcaagaaatg
    25321 ctatttgcaa ctggagtagt attgtttaca tttatattaa ttttaaactt agttttaaat
    25381 aaactttcaa ataaggcggt aaattaagat gagaaagttc aaagagaatc tattgaagtc
    25441 attagtatat ctatcagcac tatttacaat agtatcatta gtagttatag tgggatttat
    25501 atttataaag ggaattggca acatgaattt taatttctta tttagcaatt attcagcatc
    25561 aggtgatggt ggtatacttc caatgataat tacaacatta tatacagtag tggtttctat
    25621 agttgtagca actcctatag gaatattggc tgctatatat ttacaagaat atgctaaaaa
    25681 aggaaaagca gttacagcta taagatttgc aactgaaagt ttatcaggga taccatctat
    25741 agtatatgga ttatttggag gaattttctt tgtagttaca ttaaaaatgg gatattccat
    25801 agttgcaggt tcacttacag ttgcaataat aatattacca gtaataattc gtacaacaga
    25861 agaagcttta aaaacagttc ctcaagctta tagagaatca tcattggcat taggagctac
    25921 aaaatttcaa actttatata aggtagtact tccaagtgca ataccaggaa ttttatctgg
    25981 agtaatctta tcagttggtc gtataattgg agaatcagct gcaatattac ttacagcagg
    26041 tactgtagcc aagatgccag gtggaatatt tgatagtgca agaacattaa ctgtacactc
    26101 atacttactg actaaagaga gtggagatat agcaacagca gccagtatag gaattgtttt
    26161 aatagtaatt gtattagcac taaacatgct agcaagattt gttgctaaga aattaaataa
    26221 agctaattat taaatttaag aggtgtgaat aatggaatta atcgataaga taaaaatgag
    26281 tgtaaaagat ttggatttat tttatggtga taagcaagca ttaaagaaaa taaatatgga
    26341 tataaaagag aataaggtta ctgctttaat aggtccatct ggatgcggaa aatcaacttt
    26401 tataagaacg ttaaatagaa tgaatgactt aatcgaagat gtaacaatta aaggaaacat
    26461 ttctgttgat ggagaggaca tatatacctc agatgatgtt ataaatcttc gtactaaagt
    26521 aggaatggta tttcaaaagc caaatccatt tcctatgagt atatatgata atgtggcata
    26581 tggtcctcgt acacatggac taagagataa gaagcaatta gataaaattg tagaagaaag
    26641 cttaaaaggt gcagctattt gggatgaggt taaagacagg cttaaatcat ctgcactagg
    26701 actttctggt ggtcaacaac agcgtatatg tatagcaaga gcaattgcta tgagaccaga
    26761 agttattctt atggatgaac ctacatctgc tttagaccca atttcaacat taaaagtaga
    26821 ggaacttata gaggatttaa aaaaagacta cacaatagtc atagttacac ataatatgca
    26881 acaagctgct cgtatatcag atgaaacagc ttttttctta aatggagagg ttatagaatt
    26941 tagcgataca aaaactatgt ttaccactcc tgtagataaa agaacagaag actatataac
    27001 aggtagattt ggttaaaata tataactata aaggagttag acaatggtca ataatagttt
    27061 agatataagt attgatactt taaaagaaca aacagtgctt atgatggaaa aatgtgaaga
    27121 agcaatagaa aagtctgtga cttgtatgat agagaaggat ttagagggtg caagaaaagt
    27181 agtagaagat gatgaagaaa taaataaatt aagagaagaa ataagagata agagtataga
    27241 gctaatagta ttaaagcaac caatggcaag ggacttaaga tttatttatt cattaggtaa
    27301 tatatctata gagctggaaa gaataggaga ttatgcagca aatatagcta gagaaatgtt
    27361 gaagataggt ggagaggctt atataaaaga gctaatagat attcctaaga tggcaaaaga
    27421 atgtaagtct atgatgtctc agactagaga agctttaatc ttatttgatg caagtatagc
    27481 ttatgatgtt ggaactaaag atgatattgt agatggattg tatgaacaag tacaaattga
    27541 ttgtttaaaa ataatgcatg aaaactcaaa taccatagac caaggtgtaa aacttctact
    27601 tataggaaga taccttgaaa gaattggaga ccatataaca aatgtatgtg agaagataat
    27661 ttttgcaatt gagggtaaaa tggttgagat aggataaaaa actgctttaa agcagttttt
    27721 ttattgtcta aattaagaaa gaattgataa aaaaatatga ttaatgggta aatttaaaaa
    27781 attgtgatat actaggaaca tattaaatat gaggatgcgt attttatata aggtgctttt
    27841 taggaggtgg aactttgaaa cttcaaaaga tgggtatgag gactataaaa acaggaatta
    27901 gtgtcacttt atgtatgatt cttggtgact atttagtaga gaatatgttt tattctctgg
    27961 tagcatgtat aatttctgtt caagatacag taaaaggttc tttaaagacg ggaatcaata
    28021 gagtggaagg tactatttta ggtggtataa taggattcat atttgcaatc attaaagctg
    28081 gagacccatt tttatgtggt ctaggagtaa tgtgctcaat atatttatgc aatctgttta
    28141 aaataaagtc agtagtagtt gcctgtgtaa cctttctggc tatacatcta ggtgtaggaa
    28201 atagtgaccc tgtgtattat tctttacata gggtgttaga tacatctgtg ggtgttttgt
    28261 ttggagtact tgttaattat tatgttgcta gaccaaatta tctaaatagt gttatagatg
    28321 agtttaaaaa gatagaagaa ctttcaatgt tgcttattga agataaaatt cttagaaaag
    28381 aaaatttaaa tgtagagaaa tttgaagaag aagtagaaaa attagaagaa atatattcaa
    28441 aacttattga tgagttggat tatagtttga gtgaaactaa tatagaaaaa attgagaatg
    28501 ccttaaggat atgtagagaa atacattttc atatgcagtc tatagagtta cttgaaaata
    28561 aactttattt gaaagagcat acatataaat accttaagaa aacatataat gtggataagc
    28621 tagactggaa tatagatgaa gaaaaaagcc ctgtattcaa ctatcatcta atgaaaataa
    28681 tgattgaaat agagttgttg agaaagctaa ataaatcata ttaataatag tagttaaata
    28741 ataaataaaa aatagtatct ttgtaaatat taaacatata taagtttaat ttatggaggt
    28801 actatttttt atgaatacta gaaatgacaa ttctaaaata ctagaaatat ataaaatgaa
    28861 gctttttggc gaacttgtaa aagcagtgtg gaatgatgat atagaggata ttgaaaactt
    28921 acctaataaa attttaaatg aagatttaaa ggataattta aataattatt ttagtggaaa
    28981 atttgataaa gatactatgg taaatttaat tagggtaact atgggattgg atgtgacaga
    29041 agatacagat aaaaatttaa aagagtcact acatgaagct gtaaatttag atgaagtcaa
    29101 aagaccaata atatctgtaa tatcagatgc ttgcaaatat tgtgatgaaa ataataagga
    29161 agatgagtca tgtaagataa gaagtaagca tattaattgt aatgaggaag atgtatgtag
    29221 tgcttgtggt gattgtgtat caagatgtaa gttgggtgca atttcagata aaatagaatt
    29281 tataccaatg ataaaattgt taaaagatat aaagagccct gtatatgcaa tagttgcacc
    29341 agcttttgta ggacagtttg ggaaagatgt aagccctggt aaattaagaa ctgcattaaa
    29401 aaagatagga tttgaagata tgatagaagt tgctttggca gcagatatgc ttactgcaaa
    29461 agaagcatat gattattatg agcatatgaa aaaggacgaa gaaggatgct ttataactag
    29521 ttgttgctgt cctatttggg ttagtttgat acaaaatagt tttcctcaga tattggaaaa
    29581 tgtatcacca tccgtttctc ctatgattgc ttgtgggaga gctgtaaaaa ttttaaatcc
    29641 agatgctaaa gttgtattca taggtccttg tatggcaaaa aagaaagagg caatgttaga
    29701 agatataaaa gatgcagttg attttgtgct tacatttaaa gagttgcaag aaatatttga
    29761 tgcattagag ttaaatccag caataatgga tgagagtaat agagtagagg cgtccctttc
    29821 aggtagagtt tatgctagaa caggaggtgt aagtaaagca gttaagttat cagttagaag
    29881 aattgacaaa aatataaaat ttgaagaaaa ggcatttgaa ggaacaaaag agtgcatgga
    29941 cggtctaaag aaagttctaa ataaagaaat agaagctaca tttatagaag gaatggggtg
    30001 tgtaggaggc tgtgtaggag gtccgaagcg tattttaagt gtggaagaag gtactaagaa
    30061 tgttgatgaa tatagtgaaa gtacgaatat ggaaactcca tttgataatt taaatgtatt
    30121 acaattttta acttctttgg gaatcaaaag agtagaatct ttaggagaaa aagaagaaga
    30181 aaaggttaaa aaaatattta gtagagatat aaaaagtaat aagaaagaga ataaatataa
    30241 aaaataactt tttaagtctt aaacttatgc ttttataaaa gggagatatg ggggatgaaa
    30301 attaaagata ataaggctgt ttttcatgta tttataagga tatttattat agctgtttta
    30361 attttaactg gaacattatt ggaggaaaaa attaataatg ttccagttga aaatataagt
    30421 tcaaaaggtg aaaatacact ggaactgctt tctcaaagta atactttagg agaaatcata
    30481 tacaaagcat ctcaagaaga aacaaaaggt ccaggggcta cttctgaaaa agtagcatac
    30541 ataacaatag atgatggtcc atcaaaatat acaaatgcac tacttgatat tttaaaagaa
    30601 aatgatgtca aagcgacatt tttcatgctt aatcagaata tgaaaaacca caaggaagaa
    30661 gtaaggagag tcttggaaga agaaaactca ataggttttc atagtgtaag tcatgatata
    30721 cataagttat ataaaagccc agaagtaaca gttggggaat ttaatacatg caataatact
    30781 ctacaagaaa taactggtca gagttcaaaa ttaataagat taccatacgg aagtaaacca
    30841 tatatgccag aaggttcata taataaactt atggcaaatg attatttaat ttgggactgg
    30901 aatttggata cacaggattg gaagtcttct acaagtcaga tagtaagtaa tatattatat
    30961 tatggaagaa aaagagatga attagtagta ttaattcatg agaaagagca aagtttaaat
    31021 gctttaaata atattataag aatcttaaaa gagagaggat atacaatatt gccaattaca
    31081 gaaaatataa cacctaaaaa tttctggcaa gaaaacttat aataaattta aatatagtaa
    31141 aagataaagt aaattattta taaaataaat catttataaa atataattta tactttgaaa
    31201 ataaaataaa ctatcttcca aacattttat tatatgctta aaagatagtt ttgtgtcttt
    31261 aaaataaatt aaattgtata tattccttca cataactttt gtatattact aggtggttgc
    31321 catttaccat cttttttagt atatgtaatc atagttgtaa cttccttagt tggtttctta
    31381 ttgtaaaggt ctataatcat ttttgtcata tcatcttgaa cttctttttc ttttttatcg
    31441 taattctttt catcagttac ataagatttt actaaagtgt tcgcttcact cattacttta
    31501 ctagtatcta aagctttact tacaactttc aaagttatct tatccttact agaagattcc
    31561 actgttactg tcttttcaac accttgaatt aatttaacaa ttgtttcgta tatcttttca
    31621 gcattttctt taccataaag aggtgtcaat tgagcaatca ttgaaacctt gtccttgctg
    31681 ttataagttt gaatctgttt atattcagct tctgttaatg catcagaaat tcctttttca
    31741 tcatacttat acatttctaa tgcagctaaa ttagcttcaa aattcgactt tactttttct
    31801 tctgcattag aacaccctat agttagaact aaaactagag ccataatcgt agataatatt
    31861 aactttttta ccattttcat acaaacatcc tccctcaatt aaaataataa aaaatttatt
    31921 tatcaacatt ataacataaa tttgtctaac tatagaatta ttttgaatat tttaccactt
    31981 ccagtctatt ccaataccgt tttcttttgc tttatcgtat attctttttg ctgttacgac
    32041 atcttgtaca cctatcccaa cagttttaaa tacaattatc tcatcatcat cttctcttcc
    32101 aggaatagtt ccgtttataa cattccctaa atcaccacta aaatcatctt tacttatctt
    32161 accttctttt aatggaatta atatatctcc tgactcagat aaaactgcat ctgttgattc
    32221 aaaaaatatc ttagacgctc tagttaaaca gtttgggcac aactcttgca tatctggcat
    32281 atatgaacct actgcactta ttaaagctcc ttttttcact aagtttccat taagtactgg
    32341 ttgttttgat ggagtagcta aaactatcac atctgcgtta tctatggctt catcagatga
    32401 ttcaactgca actattttag tattatattt acttaatttt aagttcattt cttctgcaaa
    32461 tttttctcta ctttccttgt ttctactaaa aactcttacc tcatccaaat ttctagcttc
    32521 tatcatggct tcaagttgtg gctcaccttg tcctcctaga cctatcaaag ctccaatctt
    32581 agaatctttt ttagccaata cgtctatagc tgctccagag gctgctccag tacgaatctg
    32641 agttacataa gtaccatcca atactgcact aacttctcca gtttctccat ctaataatag
    32701 tactgttgct ggaattactg gtttgccttt ttgagcattt ttaggaaata cagatacaat
    32761 ttttattccc ccacagccta attcttctac gtatcctggc ataaataaca tactagcatc
    32821 ttgacttgga acagatatat tggttctcaa aggatttaca ctctttcctt cacaataaat
    32881 tctaaaagct tccttatcag cttcaattgc atctctcatt gtaaatactt tttttatgtc
    32941 gtcttttttt aaaagtagca tttttatacc cccaatttta ataagtctct atgctaaata
    33001 ttatagcata acatttaatt taatcttcta tttcaaatca aataaatcta catactctgg
    33061 ttttagcata gaacttatca acgctttatt tattgaaaat tctggtattc ctgctgcata
    33121 tggagttata tcatataaat caaaatatac aactagattc tcatcttgca agtaaaagtt
    33181 ttgattctct tttatacctt taaaattata tattccgata ttttcttcat cctttttttc
    33241 aagttcagct atttgtcttt taatttcttc atctataact tctttatatt tagtattatc
    33301 cttaaacaag tccattaatt ctaaaaattt tccagttctc atatccacat tatatgctat
    33361 atcttgataa aatccatgtg ctccaccact ataagtgtaa tatctcactt ttatactaag
    33421 agcagaatca gtattctttt taagttcaaa gtctacattt gcaacaaact tatttttctc
    33481 gtcaggatta tccttaagat actgctttgc ttctttatat gatttattat aaaattcaaa
    33541 tatgtcattt tttatcttat catttgtaga cctttcaaca attttatttg aatttgttat
    33601 tacaggcatg tttatagtac tttctaaata ctcatcattt ttcactattg ttttacttcc
    33661 tattgtactt actgataaag tttgtttact atttgtatta ccctttggta atgactggtt
    33721 actcataaca gtcactgctt ccttattact atttaaatta attgaagcat ctttccttaa
    33781 attattatat ttatagtcat gtttaattgc caaaacagcc attatagtca atgttaaaac
    33841 aaatacatat cttaaaactt tagcttttgt atcgacttta aaaaatttca tattatcatt
    33901 ttcctcctaa atataaatct ctcttattat atttggagtt tctagggttt tttatccata
    33961 taatttaata aaagattaat ttttatttat aaaaaattaa tctttttgtt ttaaaatatt
    34021 aatatgtctt atcaaacagt ttgaaatttc accaagaggt aattgtaaca taacagaacc
    34081 tctatcaaaa gctaccattg gcattccata tactatacaa gaattttcat cctgtccaat
    34141 tgtaaatgaa ccattttctt tcatttttaa aagtccactt gctccatcat aacccatacc
    34201 tgtaagtatt attcctattg aatttttacc tgctacttct gctactgaat caaacaaaac
    34261 gtctactgat ggacagtgac cacttattct ttctcctttt tcacaagtta cataatatcc
    34321 ttgtttatcc gtacacaatt tcatctggta acccccaggt gcaattaaca catttccttg
    34381 ttctactcta tcattattct tagcttctct tacattcata atacactgtt tgtcaagccg
    34441 ttgtgcatac atataagtaa acatagctgg catatgttga actacaacaa tccctggtgt
    34501 tgattttggt aggtctttta taatttcaag tattgcctct gtaccaccta cagatgcgcc
    34561 tatagcaata accatattat taaaacgttc cacattaccg cctccaaaaa atcatatatc
    34621 aaaaatacct ttttatcgtt tatatatagc aggttttaca tatttgtatt tagtactact
    34681 tctgttgatt acttctgcat gtcctacaaa caaaaaacta tcttttttgg tagcattata
    34741 aaatttattt ataagttctt ctcttgtttt taaatcaaaa taaatcataa catttctaca
    34801 aaaaatcaaa tcaaaatgtt gatatgagaa atcattcatt aaattaaacg gcttaaaaat
    34861 tacacttttt ctaatcttat cacaaatttt aaatgtacca tccttgttgt ctataaaata
    34921 cttcttcttc cataactcag gaacattgtt aacatttgat tctatgtata tacctctttt
    34981 agctttttca agtgagttag ttgaaatatc tgtggctatg attttaatgt tccacaactc
    35041 tttattatat ccaaaataat catccaaagt catagctatt gaatacgctt cttctccact
    35101 agaacatcct gcactccata tatttatgtt tcttatttta ttattttctt cccaaaaagg
    35161 aagtatacta ttctgtataa actcaaaatg ttgaggttct ctcataaaaa atgtgtggtt
    35221 agtactcaat ctatttatta ggtttatagc ttcatttcct gtcttatctt taaataatag
    35281 attcatatat tgactaaaag aactaagttt tttctctatc attgtattgt ataagcgacc
    35341 ttcaattaac gctctttttt tacttaaatc aataccatat tcttttttta catggtttac
    35401 aagaactata aattcttcat ctgtgagttt tatcatgcaa aaacttcctc ctgctaattt
    35461 atcagaacta actatatgct attaatcaaa aactttcgaa tatctaaaat taatatagaa
    35521 ttatcttcaa ctttcgcaat ctcttttata tctttattaa tattagtgtt gttagaatta
    35581 gtcgtctcta gtaaatttag attttctata tgaataacat caacaacttt atctacaata
    35641 attccaactt gatactcatc aacctttgta attattatac aagttctctc attataatca
    35701 gctttaggaa gattgtactt tatatgcata ttaataactg gtattattct tcctctcaaa
    35761 ttaataactc cacttatata tgttggaaga catggtacat acgttattga ttgaaatctt
    35821 atggtttcaa tcacattttc taattctatt ccataaataa catcattgac ataaaatgtt
    35881 aatacttgtt taataatttc atctttagcc atactttaaa tcccctaata tatttctata
    35941 atgctatctg catctataat taaacttata cttccatccc caagtattgt acatcccgat
    36001 aaacccttat tttttatatt aaatcggtta aaataaactg gaaatggttt cacaacaact
    36061 tgctgattac ctattatttc atcaacaaaa atgcatactg ctttatgctc attttcaata
    36121 attatcatat taccattcat cagattggtt acttttgttt gaatattata tattttatgt
    36181 aaccttataa tgggaataca tgctccatat attgtaatta actctgtctt atttccttct
    36241 gtaattattt gatttaagtc tgtaagttta aatgttcttc ttatggatga tattggtaaa
    36301 gtaaatagtg aatctccaac tttaaacttc ataccctcta ctatagaaag agttaatggt
    36361 atttttatag taaaggttgt cccctcatcc tgtttacttt ttacttcaat tgaacctcca
    36421 actttttcaa tacttttacg aacaatgtcc atgcctactc ctcttccaga aaattcagtt
    36481 atagattctt ttgtagaaaa gcctggagtc ataatcaaag aattgacctc gtcatcagta
    36541 tactcattac tttgatgttt aagaagacct tgttccttag cttttgccaa aatcttatct
    36601 ctcataatgc ctctaccatc atctgaaata cttatcacag cttctccgcc tagattttca
    36661 gcagataaaa ctatctttcc cacttcttct ttacctttcg ctatacgctc ctcaataggc
    36721 tctattgcat ggtccatagc atttcttata aggtgcataa agggttctgc taaattatca
    36781 attacactct tatctacctc tgtctctgct cctatagtta ttaactctac atttttatct
    36841 aattttttat tcatatctcg tacaattcta tgcatttttt gaaatacacc agcaatttga
    36901 atcatacgca tagacattac tatatcttgc aattcatctg taagcttgtg taattgtctt
    36961 gttgccttat tgaaattatc tatatcaaca cctgtagaat ttacgctatt tacaaccatt
    37021 gattccataa ttacaatttc tccaactata ttttgaagta agtccaattt ttctaaattt
    37081 acactcataa tactctgctt acttattggt aaatgttcat tgtcttcact tagactatct
    37141 ttttccatat cagttttttc atttaaaaca tcttcttgta tctcatcttc tgtatagtta
    37201 ttttgataac ttttacttac tttattatta tcttttaatt tattttctac tgcatcattg
    37261 tttgatgtat ttttcatttc tatttctttt ttactaatat ttatgtattc ttttacatag
    37321 agattatctt ctatagtttt ataaactatt gccttatcct ctttagctac aaattgtata
    37381 taaaacccat aacttttaat atactctgta gactctgcat ttgtttctac atcttttgga
    37441 taaaaatcta taaattcaca gtaatctcta agttcaaata caagcatgaa agctctcaca
    37501 ttttccatca tgcaaccttg ttcaaagatt atttttacta catcagagtc ttctttgtat
    37561 tcaaaatttg aatctattac ttctttttcg tctttacttt ctaaatttgc attatccttt
    37621 gatttcatag aacttgataa ttccaaagta ctcacatact cttcaattcc ttcaataaaa
    37681 ttagagtaat cagaagatat acaacctctt gattgtaact catctatatc tcttcttata
    37741 aaatctaatg attgaaagac taaatcaaat aataggtcat tgtctaaaac ttctatttta
    37801 ccttcacgta tagcataaaa caagtcttct acactatgtg ctaaagcaga tatattgtct
    37861 aaccccatca tagatgctga accttttatc gtatgcatta ttctaaaagt ttcattaatg
    37921 ttgttatgag taaatacttt ctctttttct atttgaatca taatttcatc taattgttcg
    37981 agtaataaac ttgtctcaaa tataaacata tctaacattt gtctcatact cggttcaata
    38041 taattcacat ttatcaccta cgacctacaa ataattttct attatatatg catctcataa
    38101 tttaaatcct tgatgattct cttatctcac tatatgtacc tcataattta aatacacaat
    38161 cattctctta tttcaatata tatacatctc ataatttaaa tacacgataa ttctcttact
    38221 tcaatattca cctcataatt taaacccatg atgattctct tacttcactt tcctttagat
    38281 gaaatttttc tactaattct tttaaaattt gagcttgagc agacatctct tctgaagctg
    38341 ctgcactttc ctctgctgtt gctgagttca tttggactac tatggaaatt tgctctattc
    38401 cagataaaat ctgtgtaatt gctacttctt gactatgtac agccgaagaa ataccattaa
    38461 tataattagt agttttttct acaccattta ctaccaagtc caatgcattt gcagtctctt
    38521 tagcaattct gacaccattt tctactgttt taatagcttc ttctatgaga atagctgtat
    38581 tttgagctgc ttttgcactt ttaccagcca aagacctaac ttcatctgct acaactgcaa
    38641 atcctctacc atattgacct gctcttgctg cttcaacagc tgcatttaat gcaagaatat
    38701 tagtttggaa tgctatctca tctattgttt tgattatttt tgatatttca ctcgattttt
    38761 cacttatttc acccattgat gtcatcatat catccataca tctacttccg aaaccaactt
    38821 gtgatgcaga ttggtcagat acctcacatg caagactagc actatctgca cacttcttaa
    38881 ttccatctga tatctcatta atcgtggaag ctaattcttc tactgaacta gcttgttcag
    38941 tagcaccctg tgaaagagct tgtgcacctg ctgcaacttg ttctgaagca cttgcaactt
    39001 gctctgctga taaatttatt tcagaaaaat caccattaaa agagtttatt atactttcta
    39061 aagatatttt aattgattta aaatcaccta taaattcttg gtctatctct actcttaaat
    39121 ctccttttgc aatactagtt aatgtactgt ctataaggtc tatgtaattt aaaagcatac
    39181 tttgcatctt tttgacagaa ctcactaata gccctatttc agatttactt tcttcaacgt
    39241 ctatacttgt tcttaagtcc ccagatgcaa ttcttgaaaa gtgtttttct actttattaa
    39301 taggaatcac tatttttaat tttattactg tatattctat tattgtcaat attattaaaa
    39361 gggaaagtat aaatattgtt cttaatatta gactttgtaa ttcttttttt acttctacaa
    39421 ttttggaatt tgaacgggta actatatcct cttgaaattc atttattaaa gaatccattt
    39481 tctcttggga gtttatatag tcactaccaa aaattatact ttgagcttta ctcttatcat
    39541 tactttcgac tgcctttatt gcactttgtt ctgttggtac taaagaatct gatatttctt
    39601 ttgcttctaa gattttattt gactcgctct ttgtaagacc aattttttct aatttgttta
    39661 aagctgattc tcttgttttt ccgtataatt ctttttcata aatatcttta ttcttttttt
    39721 ctcctgtaaa tacatatctt cttaatacat cacttatctc tctagttgta tcttttatat
    39781 actgactttg agtcctcaaa ttattcatat cattaatact tttttctact ttttcaaatg
    39841 ctttataaga tgaaatagaa gaaaaaatcc ctgctagaac agccaatact ataataatca
    39901 acaatacaat tgctaattta gaaagcttta cttctctttt catatctgta ctccttcata
    39961 aagtaagttt atatcttttt taatcctttc attgtactca ctacgctaca atcttttcct
    40021 aagtttttac cctcatacat tgctttatct gctaaggata tgttttcttc taatgatata
    40081 tttgagttta cttctactac tcctaatgta atagtgcact ttattttatg ttctttatag
    40141 ttgaaatcaa actcctttat ctctttacgg attctttctg aaagtatctt agcaccttct
    40201 attggagtat ttgtgagcat tatcaaaaac tcttctccac cccatcttga tacagtatca
    40261 atttgtctac aattcttttt tattatactt gatattactg ttaacacgaa atcccctgct
    40321 tcatgcccat aagtatcatt gataacctta aagtcatcaa tatcaccaag gataagggat
    40381 attgatgttt cactatattt attaattctt ctttgctcca taagctgatt aattatatgt
    40441 cgcctattgt aaagacctgt aagataatct cttacaacga gtctattcaa tttttcaaga
    40501 gaagattcca gttcattatt tatctttttt aatttatctt gagatttctt tacttcaaga
    40561 tgagctataa cacgagcttt taattctgtc atactaaaag gtttcaccat atagtcaatt
    40621 gctcctacac caaatccttt tactatgtct gtatctgtat tttttgaagt tataaaaatt
    40681 ataggtatat ctgctgtacg agcattagat tttacttcct tacaaaactc aaaaccagag
    40741 ttatctggta aaattatatc aagcaaaata atgtctggta taaattcttc aataaattct
    40801 tttgcctcta ttgcattaaa tgctttttta accttaaaat tatcttttgt aagtgtttta
    40861 tctattaagt cacacatcag aacactatca tcaacgacta aaattgttcc ctgttgctta
    40921 tttttcatat acaaacctct cttaaacata atatattcaa attttaatga tttaaaattt
    40981 ttatacttaa taattatacc actatattct taaatgttct catcacaatc tttttataat
    41041 aacactccaa ctacatccct atattacatg atagtgcaat caaacccatt gattaattca
    41101 tctattaaaa cttcatcttt atctgtcaaa agtttctcta aatctagtaa agtaattatt
    41161 ttaccttcta attctccaac tccacttaca aaataatccg aatattctat agtaactctt
    41221 ggtggaggtg atattttact tttttctaag cttactatat catcaactct atcaaccaca
    41281 aatccaacta ccaagtcctt tatttcagtt actactatat acatgcaatt tgtagtcatt
    41341 aattcatctt ttttaagtct caaactcata tctattatcg gaatgatttt tcctcttaga
    41401 tttattatgc ctttagaata tgtaggtagt tctggaataa atataatttc ttgatttcca
    41461 gtaatttcta ttaccttttc aagttcaacc ccaaaatctt gctcatctac tttaaacttt
    41521 agatacttaa ttccttcatc aattagtcca taatctaaat atgggtcatc tggaaatctc
    41581 atttaatacc tccctcctaa aatacacttt ctatgaaata tatattataa tttcttctta
    41641 cctttattta ttgaatctac aagtaattca cccgtctcag tgtaaaaacg tattgttcta
    41701 ccataattca tacctgtgtc ctcagctaat attggaatat ttaatcctaa aagagttttt
    41761 tttactgcct caacattcct atgtcctata cttgcaatta ctgaattgct acttcctaaa
    41821 aacatctgag cacctccagc aatttttgct tttatatata ttctatttgc acctatattc
    41881 tccatagatt taatgagctc atttattcct gtgtcagcaa atttacactt attttcaatg
    41941 ttaatagcat ctttactata tggcaacata acgtgtaaca ttccaccaat tccagctact
    42001 ttatctatca aacatactcc tacacaagaa ccaagtgcat aagtaactaa aacatttggt
    42061 ctataggcta tcttcatatc tgcaatgttc actactatct ctctattcat acttctaatc
    42121 ccaacctcac gagtatttct ctaagtgagc tcatttctgg aatcatcaaa atgtgactag
    42181 taaaataatt atcactcatt ttaaatttat tttctataaa taagactttg tcaccaacat
    42241 ctgaaaatct tatcataggc acatttagaa cagctccaac catatcaata catatatctg
    42301 gaattgaaac acttatagtc atgtttaaca tagatgcaat agcatttaca tatgaacttg
    42361 ccataatatt tcctatttcc ttaattgctg aaatttcaat tgcctcaatc tcatctaaaa
    42421 aagcttcttc tttattaaaa agagaactta gcataagttg agttattgat tcatccaaca
    42481 aaaacataaa cattccattg atatcacctt tcatatcgag taaaatacat actactttgt
    42541 tttctggacc accaagcaaa tttgtcgctt cattatattc aagtatcttg accataggta
    42601 ttaatacttc tacattgcta tttatcatgg atgcaagtgc agtaattgca ttcccagagc
    42661 ctatattacc aatttctcta agagcatcta tatgaacatc atcaagttct aaataattta
    42721 taatataaac ccctcccttt attattgcat ttatttactt ttcattgtat tagtgtatat
    42781 ttacactttt attttaaaac attatttaca actttaacta atgtttctgt tttgaagggc
    42841 ttcactataa aatctaacgc tccaagtttt atggcttcta caatcatatt ctcttgtcct
    42901 attgcagagc acattacaac cttagcactt gaatccaact tttttatttc tcttagcacc
    42961 tctaaaccat ctttttttgg cattgtaata tcaagcaaca tcaaatcagg cttttcatat
    43021 ttaaatatat tacacgcttc ttctccatca tttgcttcta ttaaattatt atagccactt
    43081 ttactcagag cttctttaat tatcattctc ataaaaatag catcatctac tatcaaaatt
    43141 ttattttcca taaaactaac tcctccatat gtacaacaat aaacgctttt atcttcagtt
    43201 attgtctata ctatctgact atttttcgct acacaataaa tacatttcat tgataaataa
    43261 aagtaattat ttatgccata ttatacttaa ttctcttaac ataatttgtc aacaaaaaaa
    43321 cttatatatc tattgtaata tatgtttggc gttttgacga gttattaaaa atataattgt
    43381 ataaaacata aaaagttatc aaaagtaatt aaattataat aaaacaactt tatacctttt
    43441 ttatgtttgt ataaaaaaaa ttttcagatt cattaaaatc atttctgtag attcatatag
    43501 gatttgactt tctcaatatc taatagatag ttgtttattt acttaattat atttctctat
    43561 atgtattatc gattaaatta gatttagctt tatacattat tttttatatt tttcaaattg
    43621 tatacccata aatccagaag tattctaatg tgtttataat actttttttc atattttaaa
    43681 ctaaataaca aatcattata tttacaagta tcatttatca ataaacaata ttaaatgaag
    43741 aatatgtctg aagattcaaa gtgatactga tactattaat tactaaaaaa gcagtaaatc
    43801 ttttacagat ttactgctta tagttataaa taataaaact atctataata aatgtactat
    43861 actcaatact tcattcaata tagtaataac aaatctactt tattcctata taaatatgaa
    43921 cttcttgttt ctttgtatca aaagtattac attgatactc ttcaaaatca cttatataag
    43981 tcctatcaaa atccatttgc caaaactcaa accaaaaatc tcctacttct ttttgacctc
    44041 ctactataac aaactttgca tacttacctg ctggtataac tttactaata atactttctc
    44101 caacagtatt attagtgttt aattcttcta aattcttctc tttatcagaa ttactattta
    44161 cttcacaaca tgcaacaaag ctatacggac ttgtaaaatc accctggtaa tctgtatata
    44221 gacctattgt cttgtcattc tttttaccct ttatagcatt atatatccct ttgcccataa
    44281 attttttcca caattcacct atatcattta ccgcttgtcc atctttattt gtagtctcct
    44341 tcgatattcc tataactatt ttctcattta tctctactat ttcataattc atactttata
    44401 cctcactttg tttttattaa tatattttat tttgaactaa ttcaattata atttataata
    44461 tacgacacct ttatgtcata tttttaatat aattaaactc agtgagatat tatatactaa
    44521 atgcaagata ttatatattt aataaaatct ttaatctagc attatattat aatgaataaa
    44581 ttttagacaa ctcccttagt ctagttatta cattatccct aacatcttta ggttcaagta
    44641 cttcaacatt gtcaccaaac gataaaatat atccataaat ccattcacca ataggaaatt
    44701 ctgtaattac atcatatgta tcatcttcat ttttagttat taaatcctta ttaaaatcat
    44761 caaatactct aaaaagcatc ttttctttaa acctcaattt caacgttata gtattttcct
    44821 taattacttt agaatcattc aaacatactt cttctattat ctttcttgaa aacacttcat
    44881 cctttataga taaattcctt atcctactaa ttctaaatat cctaaaatca tcttttagtt
    44941 tacaaaatcc atacaagtac caagtcttac tcttatacat aagcttcagt ggttcgacag
    45001 ttctgtttgt ctggcttgac aaactattta cataattaaa atttatagta ttacgcctta
    45061 aaatagcttc ttttattttt gtaaatttat catcttcatt aaaattactt ccccattcag
    45121 taaagtctat ttcaatccag tttgaaaaat tctgctctcc aaatattgag ccaattttat
    45181 ttactactga atttatttct ggatacttag tcgcctgtaa tgttttcagt gcaactatta
    45241 aactctcttt atcttttttt gacaatatag ccttgtctat agaatattct tctattaaag
    45301 atatccctcc tcctttgcct ttcgtcatat atactggtac tcccgacata gacagagttt
    45361 ctatatctct atatatggtt cttgtagaaa cttcaaacct atctgccaac tctttagctg
    45421 ttactaattt tttatttaat agaattacta ttatttctgt taatctattt attttcattc
    45481 attaccacct actaaaatta ttaaatttat ttaatctaaa ttaatcatac taatttttaa
    45541 ataaacaaaa tcttagaatc ttatctaaat tattcttaca tgattttatt tactttctat
    45601 tatctttctc actttggata ttatcatctt aatttattta ttactatatc aatttactta
    45661 ttatcatctc atttgttatc gtcttactta atttacttat tgctatatca attccactta
    45721 ttatcatctt atttaactta cttatttcta tatcaattca cttattatta cctcacttgt
    45781 tatcatctta cttaatttac ttatttctat atcaatttac ttattatcat ctcatttgtt
    45841 atcgtcttac ttaatttact tattgctatg tcaattcatt tattattatc tcacttgtta
    45901 tcgtcttact taatttactt atttctatat caattcactt attatcatct taattcattt
    45961 gattattatc atttacttta ttcaatttct atatcaaaaa ttagtatttg tacttaatac
    46021 ttaaaattaa tttaaagtct ttacatatta tttatttttt attgtaatat tcatttccat
    46081 actttactaa gctacttcca ctcatttatt ttaaaatttc aatttactat ttctcaattc
    46141 tatattatta tttttcaatt ttatattact aattttaaag ctttttagct attattccta
    46201 caatatttaa acaatttttt cataataaag ctatattaca atatattcaa aatatgtaat
    46261 attttagata tttttcgttg acaatgttaa atttttgttt tatccttaat taaggacatg
    46321 ttattgacat ttctgaaact tatttgaaat agttttttca ttttatttag gaaaacgtat
    46381 tatacttaag aaaacgtatt ttctcatttc agataagtaa aatatttatt cttttgagga
    46441 ggaaatcatg gaaattaata aaaaacattt tattcaagta tttttaactt gcttaatctt
    46501 ggtagtaata tgtgaattta tagggcaaag aactatagct attggaaaag cctctatagt
    46561 actgttccct atgctttatg cagttataat tggacttata ataacaccag atttattagg
    46621 taaaaaaatt aaagcgctta aaaaagtggt tggagaaaaa gaaataaata ttgctggtga
    46681 agttgttgga attgcactag taatgcttgg tataaaatat ggtactacag ttggaccaaa
    46741 cattgacaaa ataattcaag ctggaccagc gtttatcgct caagaatttg gtcatatact
    46801 tgcaccaatc gttgcattac ctcttgcatt aatgtttgga atgaaaagag aagctgttgg
    46861 agctactgca agtataagtc gtgaaccttc tttaggagtt atatcagaaa aatatgggat
    46921 aaactcacca gaaggtagtg gtgtacttgg tacatattta atgggaacag ttcttggtac
    46981 tatatacttt agtgtactag gttcaatatc tatttatagt ggtcttcacc catatgcttt
    47041 gggaatggcc tgtggtgttg gtagtggaag tatgatgaca gcagctgctg gttcattatc
    47101 taccatggta ccacctgaaa tggcagatac aatacttgcc tatgctgcaa caagcaatat
    47161 gatgtctagt ataacaggaa ttatattctt agtttttgtg tccttaccat ttactaattt
    47221 tatgtataag attttagaac caaaattttc gagaaataaa aaaactaaag aaattaaatc
    47281 tacagaagga gagtgctaat aaatgtttgc taatttaaat ttaaagaaaa gttcatatca
    47341 attattggtt atgtctgtta ttggagttat aattcttata ggacaaagaa ttagcgttgg
    47401 tacatctata gttacagctc ttcctggtat ggtgatgcta atattagctg ctatggcagc
    47461 tatgattata aaagatttat ttcctaaatc aatctttcca gcttttggat ttgcaactat
    47521 aatcggcctt ttacttagta tgccatatag tccaacatct gaagtattct taactaacac
    47581 taataatatt aactttatgg ctataactac tccactacta gcttttgcag gaatttctgt
    47641 tggaaacaaa atagaagctt taaaagaaat gtcatggaaa atagttataa tttcacttat
    47701 tgtatttaca actatattct ttgcatgtgc gagtatagct catatagttt taagtattca
    47761 aggtaaaata taggaggaat ttattatgaa taaagaacaa ttaaaatctc tagtaataaa
    47821 aactatagat gaaaatagag aaaaaatatt aaaaataggt caaggaatat acaaaaatcc
    47881 agaatatgga tataaagaat ttaaaactac agaagctgtt tcaaactttt ttgagcaaga
    47941 attaaattta tctgtagaaa aaaatatagc agttacagga tgcaaagcag atgcaaattc
    48001 tagcaagaaa ggtcctcata tatctatact tggagaattg gatggtatct catgtaaaga
    48061 acataaagat gctaatgaaa taggtgcttc tcatacttgt ggacataata ttcagatagc
    48121 tggaatgtta ggtgctgctg ttggtttagt aaaaagtggc gttttagaac atttagatgg
    48181 taaagtatct tttatggcta ctcctgctga agagtttatt gagttggaat acagagagca
    48241 attaaaaaaa gaaggaaaaa taacttattt tggtggaaaa caagaattaa taaaaagagg
    48301 ttattttgat gatatagaca tatctatgat gtttcatgct tctgatttag gagaagataa
    48361 ggctctagtt ggtcctgaga gtaatggatt tgttggaaaa aaggttaaat ttataggtaa
    48421 agaatctcat gctggttctg ctccacatga tggaataaat gctttaaatg cagcaatgct
    48481 tgctataaac aacgtgaatg cacttagaga aacttttaaa gagtctgaaa gagttagatt
    48541 ccaccctatc atcacaaaag gtggagatat agtaaatgtt gttcctgctg atgttcatat
    48601 ggaatcatat gttagagcta gaactataaa tggtatgatt gatgctaatg aaagaataaa
    48661 taaggctttg atggctggtg gaatggcagt tggagctgat gttgagataa ctgaaattcc
    48721 tggatatctt ccaatattac gatacaaaag tcttgataat ttatttaaaa acaatcttga
    48781 agatttaggt ctaaaaggaa aagttattga tggtggagat tttacaggct cttttgattt
    48841 tggagatgtg tctcatataa tgcctactct tcaccctatg attggtggtg taaaaggagc
    48901 tcttcataca agagattttg aaatagttga tgaagattta gcttacataa ttcctgctaa
    48961 agcaatggca cttacagttg tagaccttct ttttgataat gctaaggatg ctaaagatat
    49021 attagatacc tttactccag ttatgactaa agaagaatat ctaacattct tagaaaaaca
    49081 cgataaaact ttataagtct atttttataa tagggtggta tctactgtaa aagttatacc
    49141 actctttgtt tttgtaacag tatacttctt ttcttttagt ttttagatta aactaaaata
    49201 tattatcctc cttaaaactt ttagagctac gttgaaatat cagtagaact atgctatatt
    49261 ctttctaatt aatataaatt tctattctaa ttcaaggtgg tgaaaaaatg tttaatgcag
    49321 gaaatcgaat tataaataca tggttgtacc ctattcaaga tggctttgtc ttgattgata
    49381 ctggatatga aaatggtttt aaacatttca aaaaacgaat ttctaaattc aacataaaaa
    49441 tcaaagatat tcgatacata tttctaactc atgctcatga tgaccatgtt ggttttctaa
    49501 atcagattct agacgaatct cctaatacaa agattgttat gcatgataaa gctttagaaa
    49561 ttctatataa aggtcaaaac tcttttattg gtggttgtac cagccgtact gcctttctct
    49621 tttgccaaat tatgaaacta tttggaaaag gtgagcatag tttttctcca cttaaacaag
    49681 aatttgaaaa aaggtgtatt cttgtgtctg acaagaatcg taaagaaatt gaaaaagaac
    49741 taaatggaaa aattatagat acaccaggac atactgctga ttcaatttca ctactaattg
    49801 atgaaggtgt tttattttgt ggagattctg caatgaatgg atttccaagt actcacaaaa
    49861 ttaccatatt tgcagaaagc aaactagaat ttattcaatc ttggaaaaca atcatcaata
    49921 caaaacctaa aatgatttat cctggacatg gaaaaccatt tgaatgcagt aaattagaac
    49981 aaaatctaat ctatgtaaat aaaataaatt tatatcctct acataattca aaagatattc
    50041 acagattttt gtagaaaata caaagtaaat ttctttgatt aattaaaaaa tctaacactt
    50101 tactacgcta cttattttaa taacttaatc ttccactagc ttttcataaa attttgtttt
    50161 aaaattaatt ttaaagtgca tatgttattt aaatacatta gataaaattc gtcattaatc
    50221 tacttaaagc atatttaact aacaccactc aaccagaaaa ttcagaaaac tgcattgaca
    50281 caggaaaaag tttattttat acttttttta ggacatattg tggacacgtc ttaaatcgac
    50341 aagcagaatt tatattgtaa gattaaccac aatacttatt ttttaattat atttttaaac
    50401 attagggagg atattatgaa tgataacgta gttaagaaga aaaacttttt tgacaggaca
    50461 ttaaacagaa tagaaactgt tggtaataaa ctaccagacc cagttacaat atttttaggg
    50521 ttatgtgtac ttttacttat actatctagt ctagttggtt ctatgggtat atcagtagtt
    50581 catcctggta ctggagaaac tataaccgct gtaaatttat tgactgtaga acagcttcaa
    50641 attcttttag gaaacatagt cagcaatttc caagggtttg ctcctttggg tctagttcta
    50701 gtaactatga taggtgctgg tgtatgtgac aaaacaggac ttatgacagc aacaatcaaa
    50761 gcatcagtaa gcaagattcc tgaaacaaga gtaactcttg ttgtaatgac tataggtatg
    50821 cttgccaata tagcttcaga tgcaggtaca atattatttc caccattagc tgcacttgta
    50881 tatcttggtg ttggtagaca tccacttata ggtttatttt ctggatatgc agcagtctgt
    50941 ctaggatttg ccgcaaacat tatgataagt gtcaatgata tacttgctgc aagttttaca
    51001 gttccagcag ctcaaatgat tgattctgga tttcaagcca atgcaacaat gaacttattt
    51061 tttatgatag catcaacttt tgttctaata cttttggcaa catgggtaac agaaaaaatt
    51121 gtagctccta gatttggtaa atatgaagga aatgcagaac tagatgttga tggaagtctt
    51181 agtgatgtag aaaagaaagg gcttaaaaaa gctggtataa gtatattaat atatgtggct
    51241 attatagtag ctcttagtgt aatcggtaaa aaaccattct tagctgaccc agaaacagga
    51301 gatttactat caaacaatgc tcctcttatg aaaggtatgg tacctataat agcactagca
    51361 tttttcatac ctggtgttgt atacggaaaa actataggta aaataaagaa ggataaggat
    51421 gtagtctcta taatggctag tgcaatgagt gatatgggtg gatatataat actagcattt
    51481 gctgcttcac aatttttgca attattcaca aatagtaatt taggtctgat actagctgta
    51541 aagggcggag aatttttaaa atcagcagga ataaatggac ctttattgtt gataggattt
    51601 attatattat catgttttat aaatttattt ataggtagtg catctgcaaa gtgggctatt
    51661 cttgcaccta tatttgtacc aatgtttatg atggttggat acaatccagc acttactcag
    51721 atggcttatc gtataggtga ttgtataaca aatccactta gcccattatt tccgtacttc
    51781 cctattatac tagcattcac aagaaaatac gataaagatg ctggtatggg tactgtaatt
    51841 gctaatatga taccatactc tatatcattc ttaatagtgt ggactatact actaatattg
    51901 tttatggtat ttaatattcc actaggacct ggaatacttc cttcatatag catgtaattt
    51961 atttaaatct ttctaaaagg agaaataatt tatgttagat aaaaatagac ttataaataa
    52021 ttttatggat atggttagaa ttgatagccc atctaatcaa gaattagaaa tgtctaagtg
    52081 gttggtaaac tacttaaaag aaagaaatat agacgccatt atagatgatg caggtgaaaa
    52141 atatggtggc aatacaggta atgtcattgc ctatataaaa ggtgaagaag gaagtagacc
    52201 actttgttta tgtgcacaca tggaccaagt tcaaccttgt ttaggtgtaa aaccaatact
    52261 agatggtaat gtagttagaa gtgatggaac tactacactt ggtgcagatg ataaagctgg
    52321 aatagctgct atacttgaag ctttagaaca tgttattaca gaaaaaatac cacatagaga
    52381 tatttatctt tgttttacaa tctgtgagga agctggtatg catggtgtca aaaactttaa
    52441 tcctgacaac ttgccttgta aagatatggt gattttagat tctggtggag ctattggttc
    52501 gatagcatac aaagctcctg ctcaacaatc tataaaaatc tcttttcatg gaaagaaagc
    52561 acatgctggt atagaacctg aaaaagggtt aaatgctata ttagtagcct ctcatgcaat
    52621 aagcaacatg cacataggca gaatagattc attgactact tcaaatatag gtaaaataga
    52681 aggtggtgga gctacaaaca tagtaactga taaggttaca ttgactgctg aaattaggtc
    52741 tcatatacct gaaactttag agtatgagct taatcatatg gaaaaatgtt gtaaggatgc
    52801 tgcatctaaa tttaatacta cttatacttt tgaacataat atgtcttacc ctagttttga
    52861 acttagtaga gatagtcacg ttttcaagtt aagtgaagaa gcaataagac aagttggtat
    52921 tgttccaaat ccaatggtaa ttggtggtgg aagtgacgca aatatattag ctaatcttgg
    52981 atataattgt gctatattaa gtctaggtat gtatgatgta cacacagtta atgaatatgt
    53041 aaatatagac gaattatatg atactgccaa aatagtttat catatgatta aattataaat
    53101 atcataatag aactctttaa attataaaaa taaaaaccta tgtatcttca actttataag
    53161 ttatatatta gagttgtttt acataggttt tagtatttta tataataatt tgttttaaca
    53221 tttttcataa taagctttga tattttatat agtaatttgt tctaacattt ttcataataa
    53281 gcttcaatat tttgcataat aatttattct agcattttta ataataggct ctagtatttt
    53341 atattaataa tttattctag tattttacat aattatttgt tctaattttt ttcataataa
    53401 gctttaatac tttatatagt aatttgttgt agaattttat acaatataat gatttataca
    53461 gttttataaa atatcttaaa acagtatttc agtaatattt tttggtcttc ctccaccaat
    53521 actagtctct tttgcacata ttcgacctaa acctgcattt actattttat ttaatatacg
    53581 tcttgcactt ctttcactta catttagata ctctgctaac tcttttgaat cataaatctt
    53641 actttttcta ttctcattta tagcaataat ttttgcaact gactcacaac tcattccagt
    53701 ctttttagat atttcgatta ccttttcatc agatagcatc aaagaataat ttaattcatt
    53761 ttcggaagct aaaggtcctc ttatgttttc atcttcatct accaaatata taccaatttc
    53821 ttttgaatct atggagtgtc ttaatgcttt atgtgcatta ttttcagcct gatacgcagt
    53881 tactccagta ccaattccta tactaagaga aaagcccatg tcttttatct ctctctttag
    53941 attgaatagc ttatcataat tatactcatt atcagctacc cctttatgaa caaatacaac
    54001 ataatcattt cttccaagta aaaataagga accttgaatg cttcttacat agtttactac
    54061 aagcttatcc atatctgatt tttttatcat gtcagaataa tagttatcta tcttctcttt
    54121 ataatctatt aaactcaata tttcaacagc aatttgagaa aatcttgcct tacttagagc
    54181 atattcactc tttaccttgt cataactttc tttgattaat tgtatagtag cttgtaaacg
    54241 aaatacagga tagcctcttt cttttaattc attatatact gcaccaaaac cagttaacat
    54301 tatatccgtc ttattttctt caaataattt tatatgccat tctacaagtt cagactctcc
    54361 tacttccaaa gaaaatggat tacaaaatac actcgttgct ttaatatcaa attctttaag
    54421 tgcatcttcc acaacatatc tatcaactac atctatactg aatttatcta attttatatt
    54481 tgcacttttt attgcccaaa atgccttcat tatactcgtc ccacttctcg gtacaaatga
    54541 atgtggctta cttatctcat acttagattt tataaattca taaactgcac atcctgtaaa
    54601 tataatagca tcacattcgt cttcacattt agaaataact tctattgtat ctactacttt
    54661 ttctcttaca tatattttag tctttaaatc actgtctatc tgttttaaat catcctttat
    54721 cttaaaccca gagtctgaag gacctataat acccactatc ataaacttcg ctcctaatcc
    54781 ataaatatta tactttttaa aaattatatc ctcactattt tctacttcta tttaattatt
    54841 ttgaactact ccatcctatc tgcatttaga atggaataat tagcttattt ttgataaagt
    54901 aacttctcaa aatcagcact tggaataggc ttacaataat aataaccttg aattaccaca
    54961 caatctaaac tcactaaaaa ttcagcttgt tcttttgtct ctacaccttc tgccactaca
    55021 tccatatcta aatcttttgc catggctata gtgtgcttta aaactatttt ttctctgtct
    55081 gtgattcctt cctcattaaa gaaaccacaa tctatcttta atgtatcaat attaatattt
    55141 tttaacatat ttaatgaaga atatgctgaa ccaaagtcat ccatatttaa aacaatacca
    55201 tccattctaa ggtcggctat tatcttagta aataatttta tatttttaat aaataaactt
    55261 tctgtaagct ctaattctaa aaaagatttt ggtatactat atttatttat taaacttaaa
    55321 acaatttctt taaaatgtgg attatgcaaa tgtaatcttg atacatttac agagatagga
    55381 actggctctt cacctaaatc tatccatttt ctaatcaaag aacatacttg ttcccataca
    55441 tacatatcta atctgataat aaacccattc ttctcaaata gtgaaataaa tttaattgga
    55501 ggtattatac ctttttctgg atgaacccat ctaaccaatg cttctgcacc aacaatttta
    55561 tttgcattaa gattatactt aggttgtaaa tatacatgga attgcccatt ttcaagtgcg
    55621 tattccattt ccctttccat ctgtttttct tcaagtgcat catttcttat agtatcatca
    55681 taaaatatat agttattgat actttgtttc tttacttttt tgtgagcata tcctgccatt
    55741 tcacacgcat ttgtaattgg aatatgatta tccaaaattc tataaacccc aaaacatggt
    55801 actaacatat attcaaattt ttttctattt aagctatttt taatcttata aattacctta
    55861 tgaatatctc tatcagagta actctcataa aaaatgcaaa atacatctgc atacatacga
    55921 caacatatac cattagaacc aatgtttttt tgaatcaact ctgcaacata tattaaagct
    55981 ttatctcctc ctctaactcc ataaatgtca ttaattacct tgaacttatc tatatccatc
    56041 attataattg cataacgctt gtcaggatat cttttaagca ttaaacttat ttgttcacaa
    56101 aaactttcat aattgtatag tcctgttaat gtatcttttt ggtttttatg tagttgcata
    56161 agataatcta tattttttat agcaactaaa atatgtgttt gtttctcacc taacttattt
    56221 ttactactaa tctttaacat ataaattaat gcccaatagt actttttatc tattcctaaa
    56281 cgtctatact caaaatttag ttctaaatcg tcttgcttgc tattattaag actatcaaga
    56341 gattttagaa ggtggttatc attaaataat attatatcat caggatgaat taaatatttt
    56401 tttatgtatg aaaaagtttt ttcaagattt tcctttatag gaaaactaaa aatattgctc
    56461 tctgattgat aaattggagt aattaaattc gtatcaatgc aaatagataa aattatatca
    56521 tatgtattat aagctaattt ttcataagct ttagaatacc cttttatcat taaatcatca
    56581 aaataaacct tatcaactaa ctctttatgt ttaaataaaa tattattcgt cgaatcagct
    56641 aagtcactaa ttactttcat ttcattattt ctaagtttgt tcttattata atacctcttc
    56701 ttatcttggt acattctctc atcagcaact ttaattagct tatgtatatc aatattatcg
    56761 tcactccaaa tactgcccac tgctacacta tatatcatct catccttaaa ttcttcactt
    56821 aaccaactca ctaattcttc aaatagttgt tttgatatat cttcacataa tacaacaaac
    56881 tcatctcctc caatacggta aacattataa gaatgaaagt atttttttat tattacacat
    56941 gctgacacaa tagcagaatc gccattagca tgtccaaagt tatcattaat atcttttaac
    57001 ccatttatat ctacaaatac aactcctatg gatttaactt ttcctttttg aaaattatct
    57061 atatacttaa tatatttatt tctattatat gcaccagtca agaagtcata gtagctcata
    57121 taatttaatt tattttctac ttttcttttt ttcatctcag ttaataaaaa ataagatagg
    57181 gatgtcaaaa gagaggtatc tccaacagct ttatgtggat tatcaactcc aataaaccct
    57241 actactttat catcttgttt tagtgaagat gtcattaaac tttcaatttt ttgaggtttt
    57301 aaaatttcat attctattgg ctgttcttct tttatatttt ctatatcatc aattattaca
    57361 aaaccttttt gttcgaataa taaaaaccaa ttctttaatt cattaatatc aagatttgtt
    57421 agtgcctgtt tttgttcatc aacaccttca ttgcaccatt catatgtatt agttactttt
    57481 gttctatctt ctgatacttc aaaaacatat gctctatcag ctttatgaaa tttaccaata
    57541 ttggttaata caagatttac agcatcagaa aaattagatt ctgttataag atgtttaata
    57601 catccaacta ataactcctt tatctctaat ttttctgcta ttgacttact tatatcttcc
    57661 ttttctgtaa tatcaagagc tatttctaat cgtgcatgtt tgccctccca tttaattaac
    57721 ttgtccttta atataaaatg tctatttgtt cgagtattcg tattttccca tatgtaatat
    57781 tcatcttctt ttaaaataga gtttgtacaa aattcgcagg gagaatcttt cccctgtaat
    57841 gctttataac attttaaatg ggatatatca ttaagtccca ttgccttttt cccaatttca
    57901 ttaatatata aaagttcata tgtatctaaa gaagaaacat atacaatttc atccaactca
    57961 tctattaaat ttattacatc catttatata tatctccttt tattcatttt ccagattgaa
    58021 tttttaaagc ttttaaaatt ttgctatata tttggcaatg atattatact tctttatgtt
    58081 ttaaaatagt accttaatga ggttctattt tttagtaaat agaattatta ttgtgtcaat
    58141 cgtacaatag agttttgtaa tacttaattt aatatattta taattaacta tcttattatg
    58201 tatttacaat taattctcat ataaatgaca aatctccacc tcaattaagt attccaatca
    58261 tatatgagga taatacttca ttcatttaaa aatataaaac tattatatat taaaatttct
    58321 tcaataataa attatttaga ttgttacttt gatatattat ataatatcac aaaggctgat
    58381 ataaaaagac aaaaagggca atttttttat atcaaaaaaa atgttaaatt gatattatcc
    58441 atatagatgc tatatttaac aattctactt acttccctta cacttattag catatagtta
    58501 ttaagagttt gttgcaaaac aacacttagc acactttaaa aagtgtggtc taataagtaa
    58561 tcaacgaaga agacataata aagcataaaa tatgatatac ttttccacgt catcaaaact
    58621 gaggatttta ttattaatat atgataaaat atgcttaata aattaaattt taatgggaga
    58681 atagttatga aaatatttag tttcttgttg tttgtagtgg gaatatgttt ttgtattgct
    58741 ggatttatgg ggcattcctc agctttttct ggtgcaacat tgagtttttt tgcaactaca
    58801 atgatagctg taagacaagt caaaactaag aaaaaatgaa ataggcaaat cctaacttta
    58861 caagttaata ttacataagt aattagtcta aaattagata ctttttctat tacagaaata
    58921 catcatccac tttgtattct cttaaaaaaa taaaatagct atgtaaattc aagattagat
    58981 agactaactc tctatccatt tcattgtaaa atatacatag ctatttgtat tcgatttaaa
    59041 atacttagat tttcttacat aacaaataat ttctatctga ttattactca tattcattta
    59101 gtaatcactc agcaactaat catttagtat ctattcatcc gccatacggt aacctacccc
    59161 aacctcagtc aaaatatatt ctggctgagc aggattcttt tcaattttcc ttcttatact
    59221 tgccataaaa actctaagcg actgattctc actttcatag taatttcccc aaactttatc
    59281 tattataaac ttatgggtta agactcttcc tgaatactta gacatcaact caataatctt
    59341 atattcgatt ggagttaaat gtatttcttc accattaatt gacacaatat gattttcata
    59401 atctatcttt aggtttttaa cttcaaaaga ctttggagca tcattattta tattatcctg
    59461 ttgagcttta tttctaagag ccacacgtac tctagccaaa agctctgtta cactaaaagg
    59521 tttagttaaa taatcgtctg ctcctccatc taaagcttcc accttatccc tctcatgctc
    59581 tctcgctgaa acaacaatta ttttattagt ctttgcacat gccctaactc gtcctattac
    59641 ctcaatccca tcaatatctg gtagtcctaa atccaaaatt atcaaatctg ggtcaagaga
    59701 atgtataagt gatatagctg ttcctccatt atctgtctct acacacctat aattttgagt
    59761 ttcaagagat acttttataa atttacaaat tggcttatca tcttctacaa ttagaactaa
    59821 tggctttatt tccacttgtc tttcccctcc tcatcataca taggtatgct aaatctaaat
    59881 gtagctcctc cagaaggatt attaaaggcg acaatttctc caccatgagc ttctactata
    59941 gatttacata tctccaatcc aagaccaata cctcttcttt caagatttct agacttattc
    60001 ttagtataaa acctattaaa aatattcccg atatcttcat ttggtattcc ttttccatta
    60061 tctgcaactt caaatagtac ttgatttgac tcttttttta cagttagttc tatcttagaa
    60121 tttttaggtg tatgccttat agcattatca attagattta ctaacacttg ttctattaat
    60181 aatacatcca catgaacgat tattatctca tctggaatat ttgtttttat gtctctacta
    60241 ttggcaaact ttttgactct taatatagat tcagctatta tttcatcaac aacctctggt
    60301 cgtttttcaa tatccaattt tccttcatct attctggtca tactaagtat attctcaaca
    60361 gaatgagtta gccaactcgt atcttcatat atatttttca ataattctac tctagtttct
    60421 ttatctatca catcatcatt ttcaagtatt gttgaagatg aacccaatat acttgtaagt
    60481 ggagttctta aatcatgaga aattgaccta agcaagtttc ctcttaatct ctctctctct
    60541 gcctcaagat ttgctttttt atttttctca aataaatttt ctctatcaat tgccaacgca
    60601 acctgtgttg aaactgcttc taatagtatc ttttcatttt ctgtaataat atctatctta
    60661 aaacacgcaa cacctataac accaagaaca tttgattctt gaccttttat agggaaataa
    60721 tatgcactgc tgtttttaca atattttgtc ccaattccaa ctggattacc tgtcctaaaa
    60781 gcttctttta tagcttcctt ttctaatact gaatggaata tattctcact tccatcattg
    60841 ttacaaatat aaatacttgg cttacctaga ttattattct catctgcaat agtcactatt
    60901 acagttctat ttaatatatt tactaaatta gacccacaaa attcaataat ttgattttta
    60961 ttttttgctt taagcaacgt tttgttattc tcatagagca atcttatcat tttttctctc
    61021 ttatgagaaa gtctcacttc tctttttatc ctagaagtta aagtacttgt tataattgct
    61081 gccattagca taatacaaaa ggtcatagga taatcttttc tataagctaa aaaagtatat
    61141 aatggatgcg taaagaaaaa attaaatgat agcactccta ttactgaaga aagtattcca
    61201 aaaaaatatc cataggttat acttgtagca aatagtacac ctaatatgta tactagtata
    61261 atattagatt cattaaaacc taccttttca aaaactactg atattccagt agcaattgtc
    61321 ataaccaata tagtttttat gaagtcctta ataattatct ttttactgag atagccatct
    61381 tcatcataat catactcttt taagtcttca tgttgtagtc gttccttttt catttactac
    61441 aattcctcct tattgttact gtttaaattg gctctatttt atataataca attttatcat
    61501 aataaattca atcaatacat ttaattaatg tacttaaatt actaaaaggt gctgtcttaa
    61561 aatgaaaata aatctctatt tcaaaacagc acctatatat ttaaattact aatttagttt
    61621 ttacatactt aaatcaatag ttttattcaa tttcataaat tataatactt caattataaa
    61681 acatttctat ccaacaagca taaatataaa gtgggcacat atacctgcac ataaaccacc
    61741 tatagtatgc gaaagtatcg ctttaccagc caatggtctt gcatctaaag catccatcat
    61801 acctatgtgt gtacttaaat atccactcca acacataccc attgctgtga atactgctat
    61861 atcattagga gttatagcgc ctgattttat aaactctggt actaaagata ttgctgctcc
    61921 aacagctcct aatgcagtta cagggaatgc tattgcctct ggtgatgtga atccaaataa
    61981 tggttctatt atgaagctaa tcttatcacc aatagcaggt aataatttta taccttcata
    62041 tgcagctcct gtgtaaacag cttgacctgt agcagggtct gtagatggtc caaaagttaa
    62101 taacataact aatgtacaaa ctactaaaac tcctggtatt atagccatac ccatttcaac
    62161 acctaactta ccaccttcaa gtatagcatc caatgttctt tggaatacat taccatctct
    62221 tatttctcta aactcttcaa gttttgcacc tttatcattt atttgctttt cagtatcatt
    62281 tttagggtca taattataat actttttagt aaaagtcaac ataattctaa cactaataat
    62341 actacctatt attgccgcaa cattacctat tatagctggt agtacatatt ctttaccttg
    62401 agctatcata aaagttgtta caataagtcc cataccaaag gctgttccta aattacataa
    62461 agcaggtact tgatacttct taaaatattg tgtaaatgtt ttgtctttag caaatggtat
    62521 aatagctgga ttatcagata aatatgttgc aactactcct gctatactag caccaggtaa
    62581 gccccatata ggtctcataa gacccttaaa tatcttatta actaaagata ttactccaaa
    62641 ctctgaaagc aatgcactaa gtgcacctgc aagaactgcc atagccatta ttaaaaatac
    62701 tgtgtctaat aaaagcgcat gtgctgtact cattattact ttaaacatca ttcctgcacc
    62761 catgatgctt cctacatatc caaatcctac cgccaatagt acaataaata cgaaggtttc
    62821 catacttact gccttgactc ttctcttatc cgacagcttt tccatcttga aatcttcccc
    62881 cttttaattt taaattaagg ttcctaacat tggtacaaat tttttggtac aaactgagtt
    62941 ctaaaactta cactcgtaat gcaagttgtc agttttttga aataaaaaaa aattacgttt
    63001 atagaataag aatatcctct ttaatttgga tactcttatt ctattttatg ttattatatt
    63061 atcatccttt tgtttaaaag tcaatttttt ctatttttgt tgtttaattt tatttatact
    63121 ctttttatat ttttcatttt cttttatctt tgtaagtact ccatataagt tgacttttct
    63181 aaatacagta gttataaata ccaatcctaa tgcaattgaa cttgcacacg ataatgtact
    63241 caccccatat tctacagctt ttatataatt attggtcaaa acagaataca tagtattata
    63301 tattccataa cctggtacta atattattaa acagcaaaca cttaatgtag ttgctggagt
    63361 catataaatt cttgcacata actcacagta tatcgcaaaa caaactgtag ctataaaaaa
    63421 acataagttt tctgttactc ccatatttaa aagaaattta tacgaaaacc aagctatact
    63481 tccacctatt cctgctagta ttaagttttt tcctttcata ttaaatagca ctccaaagct
    63541 taaggcagta aaaaaagctg ctattacttc tataaacaaa tgcacttata tcccccctaa
    63601 cttgaagtac aatccaagta ccaagaacat tcctactgct atagatacac ctacaaaaaa
    63661 tacttctgct aattttgcaa gaccagaaat caactgtcca tctaacaaat ctcttaatgc
    63721 attagtcaaa gcaagcccgg gaactaagag cattattgct cctgctatta aatggtctaa
    63781 cgtctttatg aatccgagct ttaaaattaa aattgaacaa gaagctataa taactgctcc
    63841 aattgcattt acaaaaaagt cattaaggga agatttactt aaatacataa taacaaactt
    63901 agtcagaatc ccaacagtaa atgcagctat aaattcttcc acatttcctc caaataatat
    63961 cgaaaaagtt gctgctgcaa tacctgcaaa aaatattgtt attaaatccg agtaatagtt
    64021 atcttcactt atttcatcta aaattttctc acataattca atatctaaat tatttatact
    64081 tattgctctt gataatgagt taacttcatg aaccaagttt aggtctactc ttcttgagct
    64141 tattctttta attgctgaat gtaatttccc atctacaaat acagatgcca ttacagctgt
    64201 tggagttgca aatacatcta cgtggtctat tccaaaagat tgacatattc tagctatcgt
    64261 ttcttcaact ctataggttt ctcctccact ttgcaacata gctttacctg catttgagga
    64321 aaagtttaaa attctatcta tatccacaaa acatatctcc cattctttta tagtattatt
    64381 catattttaa tacaagatat tatttattta aactatttta aataattcat atccaatatt
    64441 tacattttat gaaaaaactt gttttttatg cttgtcaaaa tcaaatttta agcttgttta
    64501 caccataaaa tggctgaatt aatatttgac aaacactttc aaccatttat ataaccttct
    64561 aaattgtata actttttact acaaataaaa ttatatctct tttaattctt tctcttgagt
    64621 atttagctta tagtaacttt atatttatat atgtacaata taaaacatta tttttatgat
    64681 acaaaatata atttgtaaat gtatatatgt attaactgtg tatatataaa ttattcttga
    64741 ccttatcagt tttttcatat atcttcatct ataccaacca tatattaata aatgatatta
    64801 catagactta agtatattaa aaaacttaaa tttagttatt taacaacata atactctaat
    64861 ttaatctata aaaatccata cttaatataa tgcaactctt attttaacac catctattac
    64921 acaaaacaac atattaaaaa gtaaaataca aaatatccac tataaacctt attttaatac
    64981 cgaatatata ttataatata tttaatgtag cttaaatata gtttaaacat aaagaaagga
    65041 aacggtatat gctaagaaaa gataaagttc tattatctct acataaatta tgtgaaaata
    65101 tgactttaaa agaccttcaa tcagataaaa caggattcac tacaatagaa attgctaacc
    65161 attcatctct tgatagaagt aataccagta aagaattaaa taacctatac aatgaaaaaa
    65221 aagttctgaa aatatctagt aagccaattt tatttctaca tgctagtatt atagaaaatt
    65281 taattggccg tactttgaac agtgatgaat tttctataaa taattgtaat gagctactta
    65341 aatcaagtaa aaatgactca gaagatattt tttcaacatt acttggacat gattctagtc
    65401 ttaaactacc tatagaaaaa gctaaatctg ctatactcta tcctccaaaa ggtcttaata
    65461 cgttactcat aggacctact ggtgttggaa aaagtacatt tgccgaaaca atgtacaaat
    65521 atgctgtaga aagtaaaatc ttttcttctg aaagcaaatt cgtagtattt aactgtgctg
    65581 aatatgcaga aaatgctaac ttattattaa gtaatttatt tggttatgtc aaaggttctt
    65641 ttactggtgc taataaggat aaattcggca tagttgcaca ggctgatgga ggcatattat
    65701 tcttagatga aatacacaga ttaccaccag aaggtcaaga gatgcttttt cttttgatgg
    65761 acaaaggcat atacagacga ttaggagaat ctgacattgt gcacaaagct aatgtcttta
    65821 ttgtgtgtgc cacaacagaa gatatacatt cttctctgct tgggactttt ttaagaagaa
    65881 tccctgttac aatcaaccta cctgctttac aggataggtc tttaaaagaa agattatctc
    65941 ttattaaata cttctttatt atagaatcaa aatacaccaa tgcaactata aaagttcaca
    66001 aagatgtaat taaatcatta ctcctttatg attgttttgg taatataggt cagcttaaat
    66061 ctgacataca acttatgagt gcaagagcct tcttaaatta caaaactgga cttaaggata
    66121 atatagaaat agatttatcc cttgttcctg attacatcta tattggtctt ttaaaattga
    66181 atgaaaatcg tagtaatcta aataaattat cagaacttga ttatatgctt ttttatgaat
    66241 ttaatggtaa taacttagaa gttgaatata caaaagaact atctaaatac aatatagata
    66301 catcaaacaa tggatttaaa tactctacag agattcctta tctggaaaat gatataagga
    66361 gtatgtttat aaattacatg gaaaagtact ctacaaaatt actttcgata tcttcagtaa
    66421 ctcattctga ttatacaagt aatgagattt ttaaagtaat caatccaaag atttactatg
    66481 ctgttgaaca ttctttaaaa gaggctgaaa aaatatcgag aaacaaatac acaaaacaaa
    66541 cttatattgc tctttcaatg catataagtg cacttataga aaatataaat caagacacat
    66601 ataatcctaa gtacaattta tataatgata aaattttctt agataaagat ttaaatatag
    66661 ctaaaatagt tttaagtata attgaaaatg acttacaaac atctttacct aaagatgaag
    66721 taaaatttat atccatgttt ctaaatagca tgtatcttga accaaacaat caatctgaaa
    66781 gtataggagt cataatactt gctcatggaa attcaacagc aagcagtatg tgtgatgtag
    66841 caaattcatt gcttggtaca aaccattgta atgcaattga catgcctctt gatgtaaaag
    66901 taagtaccat acttgataaa actatagagt tggtaaaaga atgtgacgaa ggtaagggtg
    66961 tacttctttt aacagatatg ggctctctta tagcttttgg agaacttatt tcagaaaaaa
    67021 caaaaatcaa aactcgctca attgaaatgg tatctactcc aatagtttta gaagcagtaa
    67081 gaaaaagtac actaccagaa atgactttgg atgaattagc taattcctta agctctttaa
    67141 atccatatat tggacgagca gcaatcgatt taacagaaat aaactatcct gaaaagtcaa
    67201 gagagtatgt aataataact acttgtataa caggatatgg ttcagctatg aaagtagcag
    67261 actttataaa ttcttcactt aaaaatatta gtaaatacaa tattaattta gttcctcata
    67321 atatagaaag ttttaaaatg tataagaata aatttagtaa tactaaaatt ctggcagttg
    67381 ttggaagtgt agattttaat gtagccaaca ccccttttat acacatagag gaactactaa
    67441 atggatatgg cctagatatg ctaaacaaaa taatagaagg tacattcaat gccaatagta
    67501 ttacaaatat aaaagaaaca aatctatcat acaacagttt aataataaac tttatgaccc
    67561 aaaacttaga gcttttggac tctgttaaat tgttcaacta tgtcaattct tccttattta
    67621 caataataga attaatagat gaaaacttaa agagcaaatt taagctagga tatatactac
    67681 attgctcttt tatgatagaa agatgtttta aaaatacaac ttttccatat aataacatta
    67741 ctgaattaat tagtaaaaat catgaactat atagtttaat acgtgaagcc tttaagccaa
    67801 cagaagctta ttttaatatt ttgataccag acgaagaaat tgcttatata atagacatga
    67861 ttaatgagta tctaaataaa taaaatttat agcacttatt ttgtgcatat taattaatat
    67921 atgaaatgga ggacgagatt ttgaaaggaa aaataaaaca gttaacaata cttgcattaa
    67981 tttttatatt tataactcct gtatttgcat ttgcagatac tccaccagta ccaaattctt
    68041 caagagcagc actacttata gaccaggaaa ctaaaagaat attatttgaa aaaaacattg
    68101 atgaaaaaat gccattagcg agtttaagta aaatgatgac ctttttattg gcaatagaag
    68161 cagttgataa aaatcaagtt aaagagactg atatggtgaa aatagacaag tctacagctt
    68221 cagtaggagg ttctacttgt aaacttaaag atggtgatga aatatctcta ggagagctta
    68281 tgcagggtct aatgctagta tctggaaatg atgctgctat agccatagct aaacatattg
    68341 gtaaaactga aaagaatttt gtaaatatga tgaacaagaa agcagaagaa ataggaatga
    68401 ttgatacgta ttattttaat ccaaatgggc ttcctatata tactgaccca gaacataaag
    68461 aacctcctat tgaaaatatg tcaactgctc acgatatagt tacacttgga aagtatatgt
    68521 acgaccatta tgaaaatcaa gttacaagaa taaccactat gcaagtatat aatgatacta
    68581 aaaaggattt tacacattat aacacaaatc ctctgcttgt ttcagtacct ggtgttgatg
    68641 gaataaagac aggatataca gataatgctg gatattgcct tgcattttct atgatggtac
    68701 ctaaagatgc taaaaacgaa agaaatcata gattgatagg tgttgtactt ggtgatggta
    68761 acaagaaaaa tagaatttct tcttctgcta ctttattgaa atatggtaaa gataatttcc
    68821 attctaaaaa gatagcacat aagggtgata ttatagagac tccttgtgtt gatggtattg
    68881 atgattttaa gataacagtt aaggttgata aagatttgta tggtgttgtt tcagataacg
    68941 agaatatcaa tcctaaggta gtgtttaaaa atatgaatta tcctatccat aagggagata
    69001 ttgttggtgt tgcaaagtat tataatgact ctggtaaatt tgttggaagt gttgatgtaa
    69061 aaagtgaaag taatatagga tgtattcctt tgaaggataa gattaagatt aaggttgcta
    69121 agataaataa aaaacttgag attaaaaatt ctgtttgttt taaagcatag taaagcatat
    69181 tattaaaagg gtatgttaaa tttataaaga ctccactttg tggagttttt ttgtttttta
    69241 caaaaaatta aaatagtggc aacaattgag gatgtgaggg agagttgcca ctattttgta
    69301 tagggtatta tattatgttt ttaagctagt tttactatct tctatgttta tataataagc
    69361 cttgtatatg aatttaattg ataattaata tgaaaattat gtgaagtttt taattgatgt
    69421 aaagtaatag attctattta gacacttaaa attataataa aacatcttaa tttttatatt
    69481 tatactaatt aattctagta taaatactta ttaaatacct ttattcaaac attatttcag
    69541 atttatacta ttcttatatg ttaaaaggct gtagaaaaat tattttaaaa atcctacagc
    69601 caatactagt atcatcaaga aaatttacat cttattaaac taatttttat tcatatttca
    69661 ttatttattt taatatatta aataaacttg atagcccaga agatattttt cctattgttg
    69721 atattggatc tgacgcat
//
LOCUS       DAEOTL010000011        69213 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEOTL010000011 DAEOTL010000000
VERSION     DAEOTL010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69213
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.011"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            221..466
                     /locus_tag="KRH82_000991"
     CDS             221..466
                     /locus_tag="KRH82_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBG8654284.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            501..1226
                     /locus_tag="KRH82_000992"
     CDS             501..1226
                     /locus_tag="KRH82_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBG8654285.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGMIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            1248..2561
                     /locus_tag="KRH82_000993"
     CDS             1248..2561
                     /locus_tag="KRH82_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8654286.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            2767..3306
                     /locus_tag="KRH82_000994"
     CDS             2767..3306
                     /locus_tag="KRH82_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654287.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            3395..5380
                     /locus_tag="KRH82_000995"
     CDS             3395..5380
                     /locus_tag="KRH82_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBG8654288.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            5604..6572
                     /gene="spoIIIAA"
                     /locus_tag="KRH82_000996"
     CDS             5604..6572
                     /gene="spoIIIAA"
                     /locus_tag="KRH82_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBG8654289.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGSYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            6562..7083
                     /locus_tag="KRH82_000997"
     CDS             6562..7083
                     /locus_tag="KRH82_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBG8654290.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            7100..7297
                     /gene="spoIIIAC"
                     /locus_tag="KRH82_000998"
     CDS             7100..7297
                     /gene="spoIIIAC"
                     /locus_tag="KRH82_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBG8654291.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            7313..7699
                     /gene="spoIIIAD"
                     /locus_tag="KRH82_000999"
     CDS             7313..7699
                     /gene="spoIIIAD"
                     /locus_tag="KRH82_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBG8654292.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            7784..8989
                     /gene="spoIIIAE"
                     /locus_tag="KRH82_001000"
     CDS             7784..8989
                     /gene="spoIIIAE"
                     /locus_tag="KRH82_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBG8654293.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            9049..9666
                     /locus_tag="KRH82_001001"
     CDS             9049..9666
                     /locus_tag="KRH82_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBG8654294.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            9678..10232
                     /locus_tag="KRH82_001002"
     CDS             9678..10232
                     /locus_tag="KRH82_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBG8654295.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            10259..10948
                     /locus_tag="KRH82_001003"
     CDS             10259..10948
                     /locus_tag="KRH82_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBG8654296.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            11058..11420
                     /locus_tag="KRH82_001004"
     CDS             11058..11420
                     /locus_tag="KRH82_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBG8654297.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            11505..12011
                     /gene="nusB"
                     /locus_tag="KRH82_001005"
     CDS             11505..12011
                     /gene="nusB"
                     /locus_tag="KRH82_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBG8654298.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            11995..13065
                     /locus_tag="KRH82_001006"
     CDS             11995..13065
                     /locus_tag="KRH82_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBG8654299.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVILNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            13062..14267
                     /locus_tag="KRH82_001007"
     CDS             13062..14267
                     /locus_tag="KRH82_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBG8654300.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKVKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            14269..14484
                     /gene="xseB"
                     /locus_tag="KRH82_001008"
     CDS             14269..14484
                     /gene="xseB"
                     /locus_tag="KRH82_001008"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBG8654301.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            14487..15374
                     /locus_tag="KRH82_001009"
     CDS             14487..15374
                     /locus_tag="KRH82_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBG8654302.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            15404..15841
                     /locus_tag="KRH82_001010"
     CDS             15404..15841
                     /locus_tag="KRH82_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBG8654303.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            15875..17740
                     /locus_tag="KRH82_001011"
     CDS             15875..17740
                     /locus_tag="KRH82_001011"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBG8654304.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDDGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            17873..18685
                     /locus_tag="KRH82_001012"
     CDS             17873..18685
                     /locus_tag="KRH82_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBG8654305.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            18705..20384
                     /gene="recN"
                     /locus_tag="KRH82_001013"
     CDS             18705..20384
                     /gene="recN"
                     /locus_tag="KRH82_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBG8654306.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKKVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            20599..21465
                     /locus_tag="KRH82_001014"
     CDS             20599..21465
                     /locus_tag="KRH82_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654307.1"
                     /translation="MNKKDTMHLIFIIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKYGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKFTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKAYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(21558..22049)
                     /locus_tag="KRH82_001015"
     CDS             complement(21558..22049)
                     /locus_tag="KRH82_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654308.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(22110..22550)
                     /locus_tag="KRH82_001016"
     CDS             complement(22110..22550)
                     /locus_tag="KRH82_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654309.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            22711..23769
                     /locus_tag="KRH82_001017"
     CDS             22711..23769
                     /locus_tag="KRH82_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBG8654310.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFAI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            23911..24735
                     /gene="spo0A"
                     /locus_tag="KRH82_001018"
     CDS             23911..24735
                     /gene="spo0A"
                     /locus_tag="KRH82_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBG8654311.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            25148..26269
                     /locus_tag="KRH82_001019"
     CDS             25148..26269
                     /locus_tag="KRH82_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654312.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            26287..27162
                     /locus_tag="KRH82_001020"
     CDS             26287..27162
                     /locus_tag="KRH82_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBG8654313.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            27186..27878
                     /locus_tag="KRH82_001021"
     CDS             27186..27878
                     /locus_tag="KRH82_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8654314.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            27886..28710
                     /locus_tag="KRH82_001022"
     CDS             27886..28710
                     /locus_tag="KRH82_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBG8654315.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            28715..29782
                     /locus_tag="KRH82_001023"
     CDS             28715..29782
                     /locus_tag="KRH82_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBG8654316.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            29784..30320
                     /locus_tag="KRH82_001024"
     CDS             29784..30320
                     /locus_tag="KRH82_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBG8654317.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            30388..30993
                     /locus_tag="KRH82_001025"
     CDS             30388..30993
                     /locus_tag="KRH82_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBG8654318.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVIGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            31005..31919
                     /locus_tag="KRH82_001026"
     CDS             31005..31919
                     /locus_tag="KRH82_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8654319.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICANNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            31961..33133
                     /locus_tag="KRH82_001027"
     CDS             31961..33133
                     /locus_tag="KRH82_001027"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBG8654320.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            33180..33992
                     /locus_tag="KRH82_001028"
     CDS             33180..33992
                     /locus_tag="KRH82_001028"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBG8654321.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            34196..35521
                     /locus_tag="KRH82_001029"
     CDS             34196..35521
                     /locus_tag="KRH82_001029"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBG8654322.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            35724..36803
                     /gene="mltG"
                     /locus_tag="KRH82_001030"
     CDS             35724..36803
                     /gene="mltG"
                     /locus_tag="KRH82_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBG8654323.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            36975..37649
                     /locus_tag="KRH82_001031"
     CDS             36975..37649
                     /locus_tag="KRH82_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBG8654324.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            37636..38883
                     /locus_tag="KRH82_001032"
     CDS             37636..38883
                     /locus_tag="KRH82_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBG8654325.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            38955..40619
                     /locus_tag="KRH82_001033"
     CDS             38955..40619
                     /locus_tag="KRH82_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBG8654326.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQILIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRTGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(40716..40988)
                     /locus_tag="KRH82_001034"
     CDS             complement(40716..40988)
                     /locus_tag="KRH82_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8654327.1"
                     /translation="MSLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPREREIVQ
                     LRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(41023..42540)
                     /locus_tag="KRH82_001035"
     CDS             complement(41023..42540)
                     /locus_tag="KRH82_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBG8654328.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLNTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(42665..43486)
                     /locus_tag="KRH82_001036"
     CDS             complement(42665..43486)
                     /locus_tag="KRH82_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBG8654329.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            43677..45104
                     /locus_tag="KRH82_001037"
     CDS             43677..45104
                     /locus_tag="KRH82_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HBG8654330.1"
                     /translation="MKIKKLLIIGLSLSIFIASCPISANALDKIESIKGADKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIPNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKIVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTVAKNNAIVLVDNDSNKSV
                     LKSTIKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     repeat_region   45695..45922
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=45695..45723
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            complement(45964..46182)
                     /locus_tag="KRH82_001038"
     CDS             complement(45964..46182)
                     /locus_tag="KRH82_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654331.1"
                     /translation="MLKKLRKERGMTQNELAEKANYSRAYISDLENKRYKNINISTII
                     DLSLALEIDFLELCRYYCEEELRKRKLM"
     gene            46939..47115
                     /locus_tag="KRH82_001039"
     CDS             46939..47115
                     /locus_tag="KRH82_001039"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654332.1"
                     /translation="MDEMGKNKIITINLEDEIKSLDLDIFIKYIEIFKKKDNDSFLKT
                     LDYMKYSIKKNKAL"
     gene            complement(47121..47441)
                     /locus_tag="KRH82_001040"
     CDS             complement(47121..47441)
                     /locus_tag="KRH82_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002589185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654333.1"
                     /translation="MGLEKINELRKERGLTSEQLSKLSGVPKGTLDKILTGVTKDPKL
                     ETLKSIARVLDCTLDDFDDKPNLNKLDDINNKEIKEFAQLFLEVDDETKEYVIGLMKK
                     TLKK"
     gene            47632..47823
                     /locus_tag="KRH82_001041"
     CDS             47632..47823
                     /locus_tag="KRH82_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006774187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8654334.1"
                     /translation="MARNDLNRKKLASKLGVSPKTLSNKLKGNTEFTWKEVKQIRDIV
                     APNKTLEELFRHEKESVNN"
     gene            47944..48111
                     /locus_tag="KRH82_001042"
     CDS             47944..48111
                     /locus_tag="KRH82_001042"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654335.1"
                     /translation="MDGVRHRIKMVSNMYQLDGKPSINTVKNLVSPICWGKMTGVGLL
                     GVIQTDTKIKS"
     gene            48125..48555
                     /locus_tag="KRH82_001043"
                     /pseudo
     CDS             48125..48555
                     /locus_tag="KRH82_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904215.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            48561..49376
                     /locus_tag="KRH82_001044"
     CDS             48561..49376
                     /locus_tag="KRH82_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBG8654336.1"
                     /translation="MNNLQVIERNNKRVLTTQQLADVYETDVRNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EESYFNKKKDTLITNQLSPELQMFKQIFDTVAKQEIEQKQIKQEITETKQEIQSIKDV
                     VTLNTTDWREETRRLLVSMSQNLGGNEYINTLRKESYEFLCKRFNVDLKRRLNNRRRK
                     MAEEGVCKSRREKFNYLDVIQEQNYLIEGYVIVIKDMALKYGISSDLSKNCNN"
     gene            49396..49647
                     /locus_tag="KRH82_001045"
     CDS             49396..49647
                     /locus_tag="KRH82_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654337.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDEEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWKEFDEVAKEVAINIAMKKAETVES"
     gene            49762..49923
                     /locus_tag="KRH82_001046"
     CDS             49762..49923
                     /locus_tag="KRH82_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654338.1"
                     /translation="MLSLDISKKNVMTLKKDGKFLADIVFKDIKTGKKISVGTLNKKS
                     AGQSNQHNK"
     gene            50126..50368
                     /locus_tag="KRH82_001047"
     CDS             50126..50368
                     /locus_tag="KRH82_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654339.1"
                     /translation="METARLIAIGQIKQAEKEISRLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASTEFREFMIIQEELERDRPIDVQL"
     gene            50499..50816
                     /locus_tag="KRH82_001048"
     CDS             50499..50816
                     /locus_tag="KRH82_001048"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654340.1"
                     /translation="MNVVKGCNKQLHVTLNSTCLQDNNLSWQAKGLHLYLMTKAENET
                     IYLEDLKNKSSNGRDSTANILNELIEKGYVSREIRRDALTGKVLGGYEYKIYEESLKN
                     IEK"
     gene            50825..51760
                     /locus_tag="KRH82_001049"
     CDS             50825..51760
                     /locus_tag="KRH82_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBG8654341.1"
                     /translation="MNFDNETYFHINFEDPFTRVPNAILDNKNLTYSAIGVVTQMLRF
                     QKSGSHKIYAKSLISYRKDSKSRISSALNELINEGFVIRSKIRNDKGQIKGYRYDIFD
                     TPQIKIEEKEDVKSQPCFNIPNTVNPEIGKPGSEKTGDSKTEIQFFGNIKENSIKENN
                     NTIITINKEQEESAYIKKYYETYIGLITPNNFIELAGYLDDGMEVDVIIRAIDEATSN
                     GVKNYRYIKTILNNWIESGVKTNLDLTEYQNEYEKKKRKSNSLGGVKNDKQGKRNSQT
                     KSTEFDFNSKETRINDNELERARQALRDIGVEPRY"
     gene            51696..52433
                     /locus_tag="KRH82_001050"
     CDS             51696..52433
                     /locus_tag="KRH82_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012721384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8654342.1"
                     /translation="MTTNLKEQDRHLETLELNQDTEYKCLKCKDRLFIETDEGFKECK
                     CRKLRIAENILKNSGVSEEFRKLKFDNFNYQVDSSVAKAFTKAIEYSNYFEQIREIRR
                     NSIIFMGQVGSGKTHLSLAIANSLMNRSISVIYMPYRDSMTLIKQNIMDEETYRREVG
                     KYKSAKVLLIDDLYKGNITNSDINIMFEIINYRYLNKMPLIVSTEKNFDELLEIDEAI
                     GSRLIEMSKNYLIELKGKRLNYRIYGG"
     gene            52438..53091
                     /locus_tag="KRH82_001051"
     CDS             52438..53091
                     /locus_tag="KRH82_001051"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8654343.1"
                     /translation="MDKNKMLKTLVRKAQSGDELAFNDILNVLDKEIKINASIYAKYL
                     EGIFEKDDLIAEAQAGLWKSIMNYKIEIEYVSAYFQKVIKNNILRLVNKSKTKKFTNE
                     ILVLNKNVDSNEYTELIEFIQDEGLLVDEVIIEKERAEEIEAEKKLQMKIVKRKIRYI
                     PQPQKEIIRMYLKEYDTEKISKKINKSYNAIYSSKYRAVQNLKEMCLPEISKYNITI"
     gene            53169..54086
                     /locus_tag="KRH82_001052"
     CDS             53169..54086
                     /locus_tag="KRH82_001052"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654344.1"
                     /translation="MITAFKTKEEREKEVLEKALNSFSGIQKDRARIYLTENKVNDRL
                     FLSNLLVKYKFEIRDNLKDMERIRDEIREYKSYLKQELGNKTKIKEYINYLEGLLDSC
                     ESLICAYGNALIPLFDSINKEFTKKEICQLIGANEKILDEYYEFMKKHSKEEMSKDFN
                     FIYELIFVHHGEYRWRKGRYKDFVDCPDWEMPLFNALWSHMDNFIENNKEIQESMHSV
                     FDEVFGDISYFMNGDGTMEKSVQEINIKELISNYRDYGNSTVVFQLKKKSIIDITINY
                     KLKRQRGDVLIYKVFDSEDNELGEVHKII"
     gene            54129..54608
                     /locus_tag="KRH82_001053"
     CDS             54129..54608
                     /locus_tag="KRH82_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8654345.1"
                     /translation="MDKESIKEIVRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHIN
                     LALSEAKEVNYLEEDLSDFEDEELYILSIKKSKTRTIIMIAHIDSALKTLKLRQERLQ
                     SYEKYRALELYYFDEKTYEEIAEILNCGVVTSRRWVNEMITELGIYLFGVDGLKSIV"
     gene            54756..54959
                     /locus_tag="KRH82_001054"
     CDS             54756..54959
                     /locus_tag="KRH82_001054"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654346.1"
                     /translation="MNMINLREKIIKELNEFNIKADNVFLEYAVKHIENFMNEGIDDE
                     ELLIRGVVLGASYVVNIENKDLD"
     gene            54994..55240
                     /locus_tag="KRH82_001055"
                     /pseudo
     CDS             54994..55240
                     /locus_tag="KRH82_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424164.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            55447..55659
                     /locus_tag="KRH82_001056"
     CDS             55447..55659
                     /locus_tag="KRH82_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654347.1"
                     /translation="MKCPNCGSENIEQGISTVSESGFVIYRTGLEYNTRFSTKVSKTY
                     SDLCLDCGEIVRTYIKGETDRNWCKD"
     gene            56181..57200
                     /locus_tag="KRH82_001057"
     CDS             56181..57200
                     /locus_tag="KRH82_001057"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654348.1"
                     /translation="MSIKVKVWAKLPYIIKLEEEKDYEFSFLFDDFDLFKLNMRFNDE
                     NDFLIYNNEYPGNVCQHIELEVIYKYVDYTKYKTTKCINSNDNYFEVEVPLDKTTEIF
                     GCMNKRLNEILNFLREKSNMFWIDEFNLTHINYHSENEVRFNFYSPNVNPSSVVTSFI
                     EHTDYYMISKNFKTNNVGEDTFKNFDSNKIKMKVFNEYIDKAEKALYEYNYENFIIYC
                     SISVESFIIQYIDEIANQDDIIYKQLEKTNSNYINLYYNVLLKYLTGKSLIEVDKKAC
                     THLTRLYRLRNSLMHKGIIDSKSLEKAGIMKLDFNECNKILDSAKTSFKLVKSITVKP
                     KNDIN"
     gene            57282..57707
                     /locus_tag="KRH82_001058"
     CDS             57282..57707
                     /locus_tag="KRH82_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8654349.1"
                     /translation="MAKYEYWITEEGLIKIEGWARDGLTDEQIAFNIGINVKTLYDWK
                     KKYSNICNALKKGKEVIDRQVENALLKRALGYEYDEITYEEGQETKRVTKQVVPDTTA
                     QIFWLKNRKPAEWRDKRDIEHSGNLGDITIKVGDEEYGN"
     gene            57697..58938
                     /locus_tag="KRH82_001059"
     CDS             57697..58938
                     /locus_tag="KRH82_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018306325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBG8654350.1"
                     /translation="MAINLEINPDVFNPIYLKHQLNNNNRYQIYFGGSSSGKSFSLAQ
                     RTVLDVFKGNRNYLIVRNVQSTLKRSCLNEITKAINNFKLNEYFQVNKTNMIITCKLN
                     NKQILFCGLDDVEKVKSITPIDGVITDIWVEEATETDYKAVKQLDKRLRGKSKVVKRL
                     TLSFNPILKDHWLYTEYFDIWEDDKQYVEKDNVSILKTTYKDNKFLAEDDIKALENES
                     DKYYYEVYTLGNWGVLGAVIFKNWRVEDFSDIESTFDNFRHGIDWGFADDPFAYVKSH
                     YDRMRRKLYICDEIEAVGLLNREAAPLVSKKANGDLVICDNASPKDVAEFSDLRINAV
                     SARKGAGSIEYGIKFLQGLEIIIHPRCQNFKNEINKYKYKEDKNGNILPIAVDKDNHL
                     IDALRYSLENDMEYGGISFLK"
     gene            58943..60382
                     /locus_tag="KRH82_001060"
     CDS             58943..60382
                     /locus_tag="KRH82_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBG8654351.1"
                     /translation="MLNIYISETDLIKAQLKKESTFNLAKVIEHYILKHRPEKYQEGE
                     AYYYGNANIKNKRRYYILDGAKVDDFTKVNNKAVNNYHKLLVDQKVGYSVGKPIVFNA
                     DDNNFTKLLNELLGEEFDDTITELYLNASNKGIEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDNKRQNEVVAFIRFYFIEDIDGNKIKRVEYYTENEVIYFIEKGNSFVQELLYDEYG
                     KLTEIQEGHFRVNNKEQGWGKVPFIPFKNNEKSVSDLTFYKSLIDIYDNNISTLADNL
                     DEVQEAMYILKEYGGTDLVEFANNIRYYKAIKVGANGGVDKLEINIPVEAKKELLNRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDE
                     LERLKKQEDTQKEYDDLIPNNQDGVIDEI"
     gene            60372..61769
                     /locus_tag="KRH82_001061"
     CDS             60372..61769
                     /locus_tag="KRH82_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBG8654352.1"
                     /translation="MKYKDYWRKRFEQLEEVQNNKSVKYYLELEKQYKLAMNSIEKDI
                     LSWYNRFTESEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKIISKPWATDGLNFSERIWGKHRLALVNALHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFSDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGITAPPFHCRCRTTTAPFFSDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKYVKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNNYIEGRSY
                     LTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGEKTLTNKF
                     KIHYSKTGTHIVPAL"
     gene            61784..61984
                     /locus_tag="KRH82_001062"
     CDS             61784..61984
                     /locus_tag="KRH82_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654353.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            62050..62613
                     /locus_tag="KRH82_001063"
     CDS             62050..62613
                     /locus_tag="KRH82_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBG8654354.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYANI
                     ETQLNTANEAIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            62625..63524
                     /locus_tag="KRH82_001064"
     CDS             62625..63524
                     /locus_tag="KRH82_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBG8654355.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            63524..63757
                     /locus_tag="KRH82_001065"
     CDS             63524..63757
                     /locus_tag="KRH82_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654356.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            63767..64168
                     /locus_tag="KRH82_001066"
     CDS             63767..64168
                     /locus_tag="KRH82_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654357.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            64162..64509
                     /locus_tag="KRH82_001067"
     CDS             64162..64509
                     /locus_tag="KRH82_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654358.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELFKDKA"
     gene            64509..64799
                     /locus_tag="KRH82_001068"
     CDS             64509..64799
                     /locus_tag="KRH82_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBG8654359.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYALTQWGI"
     gene            64909..65715
                     /locus_tag="KRH82_001069"
     CDS             64909..65715
                     /locus_tag="KRH82_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654360.1"
                     /translation="MAKFLDITGKKFGRLRVIKFSKEIKSGKRNRKYWLCKCDCGNFK
                     EIRTDSLTSGLVQSCGCLKKEQDKLNLTDKYQFKKKYKVQNKRLYSIWKGIISRCTDK
                     NNKRYNRYGERNIIVCDEWFCYDNFANWALSNGYSEKLTIDRINNEGNYESSNCRWVD
                     IKTQCRNRSTNILVKHEEKEITLIELSEKTGISYSCLRSRYSKGLVGNKLIEKVKIIE
                     ESRAKLSIEDVKEIRKKYSDGYTIKQLSEIYPVTYSSISNIVHRRTWKNI"
     gene            66064..66501
                     /locus_tag="KRH82_001070"
     CDS             66064..66501
                     /locus_tag="KRH82_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654361.1"
                     /translation="MLNNIIDGISIKLDKTFGESYTIYSEDVEQGINEPCFFICPLNP
                     SKTSYPNGRTLKKNSFDVHYFPRSKDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNDTEKMNDVELFGGLKRGDNFE"
     gene            66494..66670
                     /locus_tag="KRH82_001071"
     CDS             66494..66670
                     /locus_tag="KRH82_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654362.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINNFMKGVS"
     gene            66671..67981
                     /locus_tag="KRH82_001072"
     CDS             66671..67981
                     /locus_tag="KRH82_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBG8654363.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEIFTVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATAKYSGTRGNDLKVIVTTNIDDNTKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDTTLEASAGLVFTGGTNGESVTGAEYQAFLDKIESYSFNALGSLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKVKDTGLLESSLVYWTTGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            67998..68468
                     /locus_tag="KRH82_001073"
     CDS             67998..68468
                     /locus_tag="KRH82_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBG8654364.1"
                     /translation="MFQQIKARDTISASKAECYVTIEGKRYNFMQAINLEAKMEKNKS
                     EVPILGSTTKGNKSTGSKYTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SSAGRQTIILKDCNMDSGIIVKFDADGEYLDEDMDFTCEDWELVEKFNIINGME"
     gene            68539..68979
                     /locus_tag="KRH82_001074"
     CDS             68539..68979
                     /locus_tag="KRH82_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBG8654365.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYIASDRFLDEEGKPVEWELKVLSSE
                     EDEVLRRNCTKRVKVIGNNGKPTGQFTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTTFEDKVEEAKN"
BASE COUNT        28152 a         6973 c        12472 g        21616 t
ORIGIN      
        1 ggtttttaaa ataggattag ataggtaata ggttaagtta gaataaccca ttacctattt
       61 ttatttgtaa gaaaagtgta catagaatta gaagtaaaaa atacaactaa taaaactatt
      121 gaaaatacta gataaataat aaataaaaat aattatagat tttggcatac atattgctaa
      181 ttatagagat aagacgacaa aataattggg aggtttaatg atgaaataca aaacaacagg
      241 gacttgtgct acagaaattg aatttgaagt aaaagaaaat aaagttacaa atgtaaactt
      301 tataggtgga tgtgatggaa atttaaaagg gctaaaagta ttagttgaag gcatgaatat
      361 agaagatgta atacaaaagt taaaaggaat agagtgtaaa acaaagccaa catcttgccc
      421 agaccaactg tctctagcat tggaaaatta tatgaatata aagtaataca taaaacaatc
      481 gattagttag gagtttaatt atgaaaccaa taatagggat tttaggaaat ttaataataa
      541 tggaaaatgg tatgtttcca ggtcttgaaa ggtcatatgt aaataatgat tatataaatg
      601 cagtgctaaa aggtggcggt agtccagtaa taattcctgt aaatacagat aaagaagtta
      661 taaaaaaaca gattgaaatg gttgatggag tcttaatatc tgggggatgg gatatcaatc
      721 ctcaactgta tggagaagaa acaagagaag aaacgacatt tatatatcca gaagtggatg
      781 aatttgattt aattgcaata agtatagcat tagaacttaa aaagcctata ttaggtgtat
      841 gtaggggact acaaatttta aatgtaagtt taggaggaac tttatatcaa gataataatc
      901 ttatagaagg aagttatata aaacatacac aatcttctaa aagacatgta gctactcata
      961 aagttgatgt taaagaagga agtattttag agggaatttt aggaaaacaa ttacttacaa
     1021 atagttatca tcatcaaagt gtcaatcagc ttggaaaagg attaaaagcc atagcatact
     1081 caaaagatgg tatgatagaa gctattgaga aagaggatga aaattttgta gtaggagtac
     1141 agtggcatcc agaaatgatg gtagattact gtgataaaat ggaaaaacta tttaaatatt
     1201 ttataaatat ttgttcgaat ttataatata ccttgggggg attgaacatg aacgaaaaga
     1261 acaaaatggg attaataagt attatacttt taggtattaa tgcagtagta ggagctggag
     1321 tttttctatt accaggagat gcaatgaaat catttggtgt agcaagtata tttgtatata
     1381 tatttgatat gttgttagtt ttatctatgg cattctgttt tgctgaggtt gcaggtaaat
     1441 tcaataaaaa tggtgctgcc tatgtatata caaaagaagc ttttggagat ttttgtggtt
     1501 ttgaagtagg tcttatgaaa tgggtaatag gatgtatttc ttggggagct ttaatagtag
     1561 gttttcctac atcattatca gcagtatggg ctccagcagg tgaaccacat atacaaaaaa
     1621 ttataattgt agccatgata gttgggctta caattataaa cttattaggt gtatctctat
     1681 caaaaattgt acaaaatgtt ataactgtag gtaaactaat tccattaata ctatttatag
     1741 gaataggtat attttttata aaaggagtta attttacttc ttcaacaatg gtacctccag
     1801 gagctggagc aacagagttt ggagcagcag cacttttaat gttttattca tttacaggat
     1861 ttgaatctat agcagttgca gcagaagata tggagaatcc acaaaaaaat ataccaatag
     1921 caattataag tgtaatagta attgcatcaa taatatatat attaaatcaa gttgtatgtg
     1981 ttggtatact aggagattca ttatctagta catctacacc agtggcagat gctgcaagaa
     2041 tatgctttgg aaatatggga gctggattgg ttacctttgg aacattggtt tctgttggtg
     2101 gaatttgtat gtgtggtgct tttgtaaatc caagaagttg tgtagcttta gctgatgata
     2161 aaatgttacc gagaatattt gcaagaaaag ataaaaaagg tacaccatat gtagcgataa
     2221 tagctactat gttaatcact ataccaatag ctctatctgg aagttttgct gaattagcag
     2281 caataagtgc agttgctaga ttcatacaat acataccaac atctttatcc gtattagtgt
     2341 ttagaaagaa aagaccagaa ttagtaggta cttttaaaac tccttttgga gcagtgattc
     2401 ctctaattgc tgtatgtgtt ggaacatggt tattattcca agcatctatg catcaattaa
     2461 ttatgggatt aggagctttg gcaattggag taccattata ctttataatg aagtcttata
     2521 atagaaaagt ctatggtgaa aatttaaaga aaatagttta attatgttat aacagtttat
     2581 tgagttaaag ttagacattg gcagaaaatt aaatacaaat aagtatctat aaggctatat
     2641 taaaatatta ttaatttttt attttaatat agccttaaat tgttatcaat aagtgaaaaa
     2701 tattgtaaca atagaagaac aatagtatta tgtttataga caaaaaactt attaggaggt
     2761 aaatttatgc caacaataac attaaaaaat ggtgtagacg tacttattag agaaggagta
     2821 agggaagatg ctcaaagcat tatagatttt tataatgaag tgggtggaga aactcatttt
     2881 ctgtcatttg gaaaggatga atataaaata tctttggagg aacaagaaaa tgctatagaa
     2941 tcagcaaaag catctgataa ttctgttaaa ctgattgcat ttatagatgg tgaaatagtt
     3001 gggattgcaa cgattgattc taatcaaaaa gcaaaaggaa agcatgttgg agtattagga
     3061 attgttgtaa aagaaaaata ttggggaatt ggattgggta aaaggcttat gttagacctt
     3121 atagaatggt gtaaatcaaa tggaataacc aagaagataa ctcttgtcac taatgaagaa
     3181 aattataatg ctataggatt atacaaaaaa gttggatttg aagtagaaag catactaaag
     3241 aaagaatgtt attataatgg tgtttatact gatttaatag gaatgtcact tttattggga
     3301 atataattag tgtacatttt atctcgaaaa aagtatatta agtatggtat aattaaaaaa
     3361 gaatataact taatataatt ttggaggacg aattatgaaa aatctgtgta aaatatcaga
     3421 tgattattta aacagcaagc ttaagtattt aaagttatta tcaaaacaat atccaagtat
     3481 atcaaaagca agtacagaaa taataaattt agaggctata ttaaatcttc caaagggaac
     3541 agagcatttt ataacagatg tacatggtga atatgaacca tttgtacatg tattaaaaaa
     3601 tggttctggt gtaataaaga gaaaaataga agaattgttt tcaaatacaa taagagacag
     3661 cgaaaaaaaa atgttagcaa ctcttgtata ttatcctgaa caaaagttag acctaataat
     3721 taagcaagag gaaaatatag atgattttta tagaataaat atttatagac ttatagaact
     3781 ttgtaaatat gcttctagca aatatactag gtctaaagtt agaaaactgt taccagaaaa
     3841 ttttaaatac ataatagaag aacttttgca tgagcatgtt aaaagtgaac ataaagaaga
     3901 gtactataaa agtatagttg aaacaatagt tgacatagga atagctaagg agtttataat
     3961 tgctatttct acagttatac aaaaattggt tgtagataga cttcatgtaa taggagatat
     4021 ttatgataga ggtccaagac cagatataat tgtcgataag cttattgaac atcattgtgt
     4081 agatattcaa tggggaaatc atgatatatt gtggatgggt gcagcctcag gtgaaaaaac
     4141 ttgtatagca aatgcactga ggatatcagc tagatatgcg aatttagaca ttgtagaaga
     4201 catatatgga ataaatctgt tgcctttggc cacttttgct atagaaatgt ataaagatga
     4261 cccttgtaaa gaatttattc caaaggttaa tgaccaaagt gtaacaacaa cagaaaagtc
     4321 tttaatggca aaaatgcaca aagcaataag tataattcaa tttaagcttg aaggtgaggt
     4381 tataagacga agacctgaat ttgaaatgga acatagactc ttgcttaata tgataaacta
     4441 tgatgaaggt acgattaatt taaaaggtaa aacatataaa ttaaaagata cttatttacc
     4501 tacaatagac aaaaaagacc catataaatt aactatggaa gaaagaaatg ttattgataa
     4561 attagtatct tcatttagag gtagtgaaaa attacaaaaa catgtttcat ttttgttttc
     4621 taaaggaagt atatatttaa aggctaactc aaatttactg attcatggat gtgtaccgtt
     4681 aaatgaagat ggaagcttta tgtctatgaa tataatggga aaagagtata aaggtaaggc
     4741 tcttatggat aagatggagt ctctagcaag agaaggattt ttctttaaag ataaggcaga
     4801 agaaaaactg tatggcatgg atattatgtg gtatttatgg actgggaaat gttcatcatt
     4861 atttggtaaa gatgatatga ctacatttga aagatacttt atagctgaaa aagagactca
     4921 taaagaaaat aagaacccat attttaaact tagagaaaat gagatggctt gtaaaagatt
     4981 atttgaagaa tttgatttag aacttgatga atctcatata ataaatggtc atgttcctgt
     5041 ggagagtaaa aatggagaga gcccaataaa agctaatggt aaaattctcg ttatagatgg
     5101 tggtttttct agggcttacc aaaaaactac tggtatagct ggatacactt tgatatacaa
     5161 ttctagaact ttgcaattag tatcgcatga accatttaat tctgctgaag aagccattgc
     5221 aaatgaaagt gatatcttat cgacaactgt tgtagtagag cataaggcaa agagaaaaat
     5281 ggtgagagat actgatgaag gagtaaagat acaagaggaa atagaagatt taaaactact
     5341 tttaatggcg tataagaaag ggctaataaa agaaatgtag atgttataga ggcacttcat
     5401 gattgaagtg tctttttgtt aatacttatt aaatatatta taaagattaa taatagtagt
     5461 ttatattata cttactaagt gaatccaaga taaatgggtt cacttttttt atttataaac
     5521 attattaaaa aaatatagat gttttggtta tattccttgt cctttataaa tagaattata
     5581 taaacaaagg aggaggacaa gagatgaata aactttctga tgaaataata aactctcttt
     5641 ctacaactat aagagaaaag gtagaaaaag tctcaaacaa taatctgaac atagaagaaa
     5701 ttaggttacg ctcacaaaaa ccattgatac taaatgcaaa ctctaaagat tatttttaca
     5761 atcaaaaaac tatgacactt gatttaaatc aacaaaactc atatgtagta acaagagaag
     5821 atgtagagca aacttttcaa ataatatgta aatattcaat acattcattt atggatgaca
     5881 taaaaaaagg attcataact ttgagaggag gtcatagagt agggttagtt ggaaaagcaa
     5941 tagtagaaga tggacaagtc aaaaatataa agcatatatc atctttaaat ataagggtat
     6001 caagggaaat tattggatgc tcggataaga ttttaagtca tatcataaag ggaaaaaatc
     6061 agattaataa tactttgata atatcaccac ctcaatgtgg aaaaacaact ttaataagag
     6121 atatagtaag aaatttaagt aatggtaatg aagattatgg atttaaaggt ttaaaagtgg
     6181 ctttagtaga tgagcgtaat gagatagcag gatcttatct aggtgttcca caaatggatg
     6241 tgggaataag gactgatata atagaaactt gcccaaaaga cttgggtatt acaatgcttt
     6301 taaggtctat gtcaccaaat gttattgtga cagatgaaat tggaagtgaa aaagaaataa
     6361 aggcattata cacagcatta aatggaggta taggattaat aactactgtg catggagatt
     6421 caatagagga tatacaaaat agaaaagaat taaatagact tctggataaa gagttattta
     6481 aaaaggttat aattctttct gcaaaaagag gagcaggaac aattgaaaaa atttatgatt
     6541 tagaagaaaa gagatggtat tttgcaaatt aaaataatta ttatagcttt cttgatagga
     6601 agtagttatt tgataggtga acaaatatac aaaacttata ctcgtagaca taaacaatta
     6661 aacgatttaa taagagtttt agaaattttg aggatggatt tatcttttgg actttataca
     6721 ttagaagaaa tctttaatag gataggtgga aataaagagt tttgtttttg gaaatttttc
     6781 tatcaaatat cagaaggact tcacaatgaa caaagtaaaa ctttggaaat aataatatca
     6841 gaaaatattg atgtattaag taaagaaact tatctaggca ataaagaaat tgaggaactg
     6901 aaaaatctaa tacttacttt agggaaaagc gatatagagt cacaacaaag aatgatagat
     6961 ttatctatag aaaatttgaa aaaacaaacc tatgagacaa aggaagatat aaacaaaaaa
     7021 ggcgtattgt ataaaaaatt agtgacattc ataggtatag gtatatgtat tatattgatt
     7081 taatatgggg aggtttatta tggaaatatc attgatatta aaggttgcag gtgtcggtat
     7141 tctaatatca gtattgaata tgatattgga aaaaacagat agaaaagatt gggcaggtct
     7201 tactacatta gcaggtgtaa taatcgtatt gggtatggta ataacagaaa taagtgactt
     7261 gtttaatact gtaagaacaa tgtttcaact ttactaaaga ggagggagta atttggaaat
     7321 aatgcaatta ataggaattg caatcatttc aactacactc tgtttagtaa ttaaaaaaga
     7381 tagaccagag atagcaaatt tcatagctat aataactgga gtaataatac tattgtcagt
     7441 tatgtttaag ctaaatttta tagtagatag tatacaagat ttggctaaca aggctaacat
     7501 cccgactatg tatatatcat taataataaa attaattggg atagcatact taatggaatt
     7561 tgcgatacaa ctttgtaaag attgtgggga aggaaacatt gcttcaaaac tagaatttgg
     7621 aggtaaaata atagttatgt caatgtcttt ccctatactt ttgtccattg tagaaatggt
     7681 ggtgaatata attccataga tgtgtatctt ggaatgaata taagtatatt agagagcttt
     7741 cgttgtattg aggtttatag agtgaagaga ggcatggttg cttatgaaaa aaagattttt
     7801 accaatgatt ataggttttt tatttacttt cttttttgta aatatctttg ctattatgat
     7861 atttgctaat gaagtaccaa gtagtgaaga taaagaatat ggtgaaacaa aaaatagcat
     7921 agataagtat atagatggtc aattagacaa gctagatata aatgagattc aagactatat
     7981 aaataaagaa atagttatta atgatgttaa tttaaaatca tttgtaaaag atttaattag
     8041 tggagaaaaa aatatcttag atttattcaa taaagatgga ttgaagatat tgatgtttga
     8101 tgaatttaaa gcaagtttaa aggtagtagc agtaattttg gtactggctc tgctatcatc
     8161 tattttaaag agtctggaaa actctttttc atcaggtgca gtaagtcaaa tagcaacata
     8221 tataatattt atcacaatgg tatcacttac acttattggt tttaaagatg tattacagat
     8281 ttgctatgat gcaatagacc atactgtagg tcttatgcaa gttataatgc caatattaat
     8341 aacattttta cttttaattg gattcccaat aacgtcgact actttgaatc ctatcttcat
     8401 aggaggagta acatttataa atgtattttt taaaaatttt ctatttgtat ctattactgt
     8461 tgcatttgga attttaataa taaacaattt atcaaaaaat ataaggctaa agagattttt
     8521 ctcctttgta aaacaaataa attatgtttc tattggagct atgtttactg tttacttagg
     8581 tcttgtatcc atacaaggac tgtatgtaac cagttttgat aaattcagtg tgaagactgc
     8641 taaatttgct ataggtaatt ttattcctgt tgtaggtgga tttgtatctg actctgtgga
     8701 tattttatta tcttcatctc agcttataaa aaatatattt ggaggaatag ggcttatctt
     8761 acttgttgga atttgcttac ttccagtaat aaaaatttta tcagtaatag tagtgtacaa
     8821 attagcagca ataattgtag aacctgttgg agaggatgga atatctaatt ttttaaatga
     8881 agtggcaaat ttaatgataa taatgctagc atcagtaatt gctataacag taatgttctt
     8941 tgtaactgta gctatcttga cctcgataag tgtcgtaagt caagggtaat ttatatatca
     9001 gtgaaaaata attacattta atctaatatt tttagagagg aggatgctat gttagagggc
     9061 ataaaggcat ggatagttag tgttttgata ggagcattta tagtaaatat agtagatatg
     9121 attttaccaa gttctaagat aaaaccttat gtcaacctag ttttaaactt tatgtttgta
     9181 tttattgtaa taactccagt agtaggattt ttttcaaaag atatgagttt agaagataga
     9241 atattaaaat ctatgggaaa ctacaacaag cagtatgtag atagtacaaa tgctttggca
     9301 aaagagactg gaaataatag tctatccaag ggatatgagg atgggttaaa agaagtactt
     9361 aaattaaaac ttgatgaata tggttatgat ttagaagata tagagcttaa tggggcaaat
     9421 ataaataata taaaaataaa agaaaagaat aatagtgcaa aaagtaataa cagttccaat
     9481 gaagaaaata aaaataatag tactaaaaga gaggaagaaa acataaactc taatgacaaa
     9541 gaaaattcta aacaagtctt caaaaaaggt acagagtatg ggttgaacct aaatgaagaa
     9601 aaattaaaaa acgacttaat aaaggtgctg gatgtttcta tagaagatat acaaattgat
     9661 aaataggagt tgggagaatg ttgaaaaact taaatgacaa agataagaga aaggtatatt
     9721 cactaataac tatagcagga atatgtgtgg tttcattagt attattatct tgttttccta
     9781 gtagcaaaag cgataaacaa gttggaaaaa cagagactaa taaaaatgct gaaaagcaag
     9841 tcactaaaga acaagaaaaa gatgatttag agtcaaaatt aacagcaata ctatctaaaa
     9901 ttgatggtgc aggagacgtt gatgtaatgg ttacatttga atcaagtgaa gaaatacaac
     9961 ctgcttttaa ttcaaataat acaacagaaa caacagagga aaaagatgca caaggtggag
    10021 aaagaacagt tacgacttct agtgaaaata aaacaatgat aacttcaaat tcaagtgacc
    10081 ctgtagttat aaaaactaca gagccaaaga taaagggagt gatagtggta gcaagtggag
    10141 caagtgaccc aagtgttaaa gagacacttt atagtgcagt acaaacatca ttacaagtag
    10201 ctggtcatca agtagaaata tattctaaat aaatacatat aaccgggggg ataaatgaat
    10261 gaagtttaat tataagggaa gaggatttgt aataataact ttaactgcaa tgttagtggt
    10321 agtaggaaca gtgaattatc aattaagtaa gaaatcttta ttagaaacat caaaagagtt
    10381 taaggcatat gaagaagcac agttacaaaa aaatactgat gagagtgata gtagtaagac
    10441 agaggattct agtaatatag ataaacaaga tggtaaggaa agtgctgata ttgatatagt
    10501 tgatagcaaa gctagtaaag taaaagaaaa ggcaactgag acaagtaagg aaataaaagc
    10561 tcaattatca tcagagaaaa atatgaaaaa ggcatcttat attttagata tgaaaatgaa
    10621 tagagaaaaa caaagaaatg agttagttca agatttaaat gaaatgataa ataatccatc
    10681 tacaacagaa gaatctagaa aagaagcttc taatatgaaa ttaaatatag ttaaaattca
    10741 agaaaaagaa cttcaaatag aaaacctttt gagtacaaaa gggtatgaag aagcgttagt
    10801 ttatataagc gataacaaag ttaatgtagt tgtaaatgaa gctaaattag aaaagaaaga
    10861 tgcagcaaaa atatttgatt tagttgcaga acaagccaat gtgaagtatg aaaatattaa
    10921 acttacaaat aataatagta ataagtaaag tataaacctc agaattaact gaggttattt
    10981 tcttgcaaag tagacttgta tttggtatta ttatacttat aaaaatagtt ccttaaaatc
    11041 aggaggtaag ttttaatatg gaagataata aatttggaca agtaaaaata tctaatgatg
    11101 taatagctac aatagctggt ttagcagcat tagaagttga aggcatagaa actacagcaa
    11161 cattaacaga taagttgtta aaaaataatg gagtaaaaat acaaatcgaa gaagaggatg
    11221 ttaatttaga tgtaatggtt acgataaagt atggaatgtc aataccagat acagctttta
    11281 aagttcaaga aaatgtaaaa aatactgttg agacaatgac aggactgaag gtttctcaag
    11341 taaatataca cattcaagga atcagcttta agaaggataa agttgataaa gaagaagcaa
    11401 aagcaactaa gaaaaattaa tattagccct ctgaaaagtc agagggtttt ttgctggtaa
    11461 ttgattttat atggataatt aaacttaaag gagaattttg attgatgaaa aaagataggg
    11521 cacaaaagag tacaacaaga gaatatataa tgaaacttat ataccaaata aatattaata
    11581 aagaagattt tgaaacttta gaagataaag tagataattt tttaaaagat aattcagaac
    11641 atattataaa tagatataaa gaacttgcac ttcaatactc aaaaaataca aatttaaagt
    11701 tagaagatac tgaaattgaa gatgttatag acaaaaaata tataaataca gtatgcaaag
    11761 cattgaaaga aaatcatgac aaaatagatg agttaataaa taagcatgct aaaaactgga
    11821 cagtagatag aatgccaaag gtagatgttt ctatacttag attgtctgtg tgtgaaatac
    11881 tttatctaga cactcctaat aaagtatcaa taaatgaagc agtagaactt gcaaaaatat
    11941 attgtgatga taagtctcct aaatttataa atggtatatt gggaagtgtt gttgatgaaa
    12001 ttgggaaata atataataat tggaattgat actagctgct atactacttc tatagcagct
    12061 atctctttag ataagaaagt tatattaaat gaaaaaataa tgttagaagt aagggataat
    12121 tcaaaaggtt taaggcaaag tgaagctgta tttcaacata tcaataattt agggattctt
    12181 agtgatagga taaaatcttt taaagataag tttaatgtag aaggagtttg ctcatcaaaa
    12241 aaaccgagac ctgttgaaaa ctcatatatg cctgtattca atgtaggtca taattttgga
    12301 aaattattgt ctagtatata tggttgtagg ttttatgaga ctactcatca agagaatcat
    12361 attgaagcaa gtttattaaa tagtaaatta aaaaataata ataaatttat ttctgttcat
    12421 atgtctggtg gtactacaga gatactttta acaagcaaac aagatagtca tcacaatgta
    12481 tgtgatacta atttaggtaa aattgccaaa ataagtatta aaaaagatga taaaagtaag
    12541 ttatacaata attttggata taatatagat ataattggag gaagtaaaga tattagcttt
    12601 ggtcaactta tagatagagt aggaattaag cttggatata aatttccttc aggaaagtat
    12661 ttggatgaaa atgctttaaa ttgtaatctt aaaatagaaa gtggtctgaa aacttctgta
    12721 agagatgggt atatgaattt atcaggatta gaaaatcagg taaataagat tataaatgat
    12781 aatggagata atactaatca aaaagaatat atatctaaat tggtattaga ttcagtagtt
    12841 agaaatatgt ttaaatcttt agtgtattta tgtgaaactt ataatgtaaa tgaagtagta
    12901 tttgctggtg gagtttctgc aagtaagtat attcttagag aattaagcat gaagttaaga
    12961 aaaaagcata tagaagctta ttttacagaa ccacaatatt caactgataa tgctgtcggg
    13021 tgtgctataa taggattgaa taacttttta ggagaaagag tatgaaacta agagctttag
    13081 atataagtga agcaaactca tatattaaaa gaattttaat aaacgaccca atactttcta
    13141 atcttaaagt taaaggagaa atttctaatt ttaaggttca tagtagtggg aatgtatatt
    13201 tatcacttaa agatgaaaca tcaaagttaa actgtgtaat ttttaaaagt aattttaatc
    13261 gcaatttaaa attagataat ggtgtaaaaa ttatagctaa tggatatata tcagtctatg
    13321 aaagagatgg tgcgtatcaa ttatacatta atgaaattga aatagaggga ataggaaatt
    13381 tacacataga gtttaataga ttaaaggaaa aacttaataa agaaggatta tttgacccta
    13441 aatacaagat acctatacct aaaatgccaa actcaattgg cgttataaca tctccaacag
    13501 gtgctgttat aagagatata ataaatgtaa taaaaagaag atatccgaaa gttaatataa
    13561 agctttatcc agtaacggtt caaggagata aatcagctga agaaatctgt gaagcaatta
    13621 gatttttcaa tcatatgaag aatgttgata cacttatagt tggtagaggt gggggttcaa
    13681 tagaagaact ttggtctttt aatgatgaaa tggtagcaag agaggttttt aattctcaaa
    13741 ttccgataat atcagcagtt gggcatgaaa cggattttac tatttgtgac tttgtgtctg
    13801 atatgagagc cccaacgcca tcagcagcag ctgagattgc tactccatca ttggatgata
    13861 taaactataa acttggaaac ataaaaagta ggatgagtaa gtctcttaca aatcaaatag
    13921 agctagacca atataggtta gaaacagtat ttaataagat aaataactat ttagattcgt
    13981 acacaataaa agataaagtt atacaattag acaaaatata tgataaaata atttttggaa
    14041 tagaaaataa tttaaaatta gaagatgaaa aattagtaaa aattggagca ttactccata
    14101 atttaagtcc attagctact atggatagag gttatagtat aactcaaaaa aatggaaaag
    14161 taataaatag tataaaagga ttaaaagtaa aggatagtat agatatagta ttaaaagatg
    14221 gaaatttaga atgtatgata gataaaattg aaaataaaga gggatagtat gaatttaacc
    14281 tacgaagaag cttataaaag attagaaagt attttaagtg aattagaatc taaaaatgct
    14341 agcttggatg aatctttaag cctatatgaa gaaggtataa gcctttataa acattgtaat
    14401 aagcttttag atgatgctaa attgaaaata agtaaattta atcaattggg aatagaagaa
    14461 gactttaaaa tagaggagga ataaaattgg aatttaaaca atgtctaaaa gaaaaagcaa
    14521 gttttgtaga aaaagtactt aaagaatata tgcctaaaga agaagggtat caaaaaactg
    14581 ttattgaagc tatgaactat agcttaagtg ctggaggtaa aagattaaga ccaatactta
    14641 cattggaggc ttgtaaaata gttggaggta atgaagatga agctattcct tttgctattg
    14701 caattgaaat gatacataca tattcactaa tacatgatga tttgccagct cttgacaatg
    14761 atgatttaag aagaggaaga ccaacaaatc ataaagtata tggagaagct atggggattt
    14821 tagcaggaga tgctttgtta aactatgctt ttgaagtaat gcttgcaggc tcaatcaata
    14881 aagaaaatcc agaaaagtat ctaaaagcta taaatgaaat tgccaaaggt gctggtatat
    14941 atggaatgat aggtggtcaa gtagtagatg tagaaagcga aaataaacaa attgaaaaag
    15001 aaaaattaga ttatatacat atgaataaaa ctgctgcaat gatggtaggc tgtatgagag
    15061 caggagctac tataggtgga gcaaattctg aacaaatgga agaaataact aaatatgcaa
    15121 aaaatatcgg attatcattc cagatagtag atgatatact agacatagta ggagatgaag
    15181 ctaagttagg taaaaaggtt ggaagtgata tagaaaatca taaatcaaca tacccatctc
    15241 ttttaggttt agataaatct aaagaaattg cacataattt gattgatgaa gcaaagaaaa
    15301 gtatagaaaa attatctgat gatgtagatt ttttaaaggg attggctgaa tatataatag
    15361 atagagaata ctaaaatata cagctaaaat cgaggaggga aaaatggatt ttttttcgga
    15421 gatttttaac aatggggctt tgggaataag tctgattgct tgtttcttag cacaatttat
    15481 aaaaatattt actggtaagg aaaaaagaat tgagttatca agaatactta tttcaggagg
    15541 tatgcctagt tcccatagtt cttttgttac aagtttagct acagtggtag gtattgaaaa
    15601 agggtttaat tctactgatt ttgctataat taccgtgctt gccttaatta taatgtatga
    15661 tgcagcaggt gttagacggg ctgttggtaa acaagctact atattaaatc aaatggtggc
    15721 agatatacag catggaaagc atatagagca gaagaaatta aaagaattaa taggtcatac
    15781 accactagaa gtttggtttg gagctttact tggaatagta acagctttaa tattgatgta
    15841 aattgaaaat ttacagaata aaggtgagga taatatgtat aaatatttag ataaagtaaa
    15901 ttctccaaag gatataaaaa atatgagtat agaagaaatg gatttacttg caaaggatat
    15961 aagaaagttc ttagtaaaat ctgtttcaaa gacaggagga cacttagctt ctaatctagg
    16021 agtggttgag ttaacattag cacttcataa agtatttgat agccctaaag ataagattgt
    16081 atgggatgta gggcatcaat cttatgttca taaaatagtt actggaagaa aagattgttt
    16141 tgtatctttg agacagttta atggactaag tggttttcca aaggagaatg aaagtcctca
    16201 tgatattttt gatacaggac atagcagtac atctatttct atagctacag gtattgcctg
    16261 tgctagggat ataaaaaaag aaaactatag tgttatatct gtgataggag atggttctat
    16321 aacaggaggt atggcacttg aagctttaaa tcaattagga tatatagata ccaatatgat
    16381 agtaatcctt aatgataatg agatgtccat agataaaaat gttggaggaa tgtctaaata
    16441 tctgtcaagt attataagaa actcaacagt tgagaaaatg acagatgaag ttgataaaat
    16501 tttaaatgtt acacaaacag gtgaaatttt atctaagact gcacatagat ttaaagataa
    16561 actaatgtat agcttttctc ctcaggactg ttcatttttt gattcattag gtataagata
    16621 ttatggacct atagatggcc ataatactaa agaactaata gatatattga gaaaagctaa
    16681 acacaaaaaa gggcctgttc ttttacatgt aattacgaaa aaaggaaaag ggtacagatt
    16741 tgcagaagaa caacctgata aatatcatgg agtatcaaag tttgatataa agacaggtgt
    16801 tacatctgca aaagttaagt ctatgtcaat tagtgttgga gaaaaacttg ttgatatggc
    16861 taatagtaat gaaaatatag tagcaataac agctgcaatg ccatctggta cagggctaaa
    16921 cctgtttgaa agtgcatatc caaaaagata ttatgatgtt ggtatagctg aacaacatgc
    16981 aacaggattt gcagcaggtc ttgcaaaaaa tggtatgaaa ccttactttg ctgtgtactc
    17041 atcatttttg caaagggcat atgaccaagt tattcatgat gtatgcataa caaaaaagcc
    17101 agttactttt cttatagata gagctggatt agttggaaat gatggagaaa ctcatcatgg
    17161 tatgtttgat ttaagttact taaattctat tccaaatatt gtagtaatgg ctccaaaaga
    17221 cacaagagag atggagctta tgatggattt gtcattaaaa ttagattgtc cactagcaat
    17281 tagataccca agaggaagta gttattacct agataaggga gagtatggag agattgtact
    17341 gggtaaatat gaggtattag atgacggtca agatacagtc atactttgta ttggaagtat
    17401 ggtaaaacat gctttagagg ctaaagaaat attatcaaga gaaggaataa atccgacaat
    17461 agttaatgct agattcttaa agccaattga tgaaggtatg ttaaaagcat tattaaaaaa
    17521 tcataaaaat gtagttacta tagaggataa tattgtaact ggaggatttg gaagtagaat
    17581 aaataagttt attatagata atgaatataa cgtaaatata cttaatatag caataccaga
    17641 agaatttgta aaacatggca atatagatga attatatgat tttgtaggat tatcgccaaa
    17701 aagtattgct gataagataa ggaaattagt tattgagtaa aagtctaatg tagatattgt
    17761 aaattaaaat ttatataaaa tatagaattt atcaattaga ataaatatca agtgtgttac
    17821 ttcaagctac tttagttatc attaaagtag cttttaacag aaaggtaatt gtatgaaaaa
    17881 aagaatagat ttattattag tagaacaagg gtactttgaa agtagagaaa gagccaaaaa
    17941 agcaataatg gctggattgg tttttgttga taatcaaagg tgtgataagg ctggtacaga
    18001 agtaaaagaa gattgtagta tagaagtaaa aggaaatcca ataccatatg tcagtagagg
    18061 tggtttaaaa cttgaaaaag caatgaaaaa ctttgatttg actattgatg gaaaggtatg
    18121 tatggatata ggggcatcca caggtggttt tacagattgt atgctcaaaa atggagcaat
    18181 aaaagtattt tctatagatg ttggttatgg tcaacttgca tggaaattga gacaagatga
    18241 tagggttgtg tgtatggaaa gaaccaatat aagaaatgtg acaatagaag atacaaagca
    18301 gtttgctgat tttgcgtcaa ttgatgtgtc ttttatatcg ttaaagttag tacttccaaa
    18361 ggcaaaggag ttagtacgtc atgatgggga agttgtcgct ttaattaaac ctcaatttga
    18421 agcaggaaga gaaaaagtag gtaaaaaagg agtagttaga gaaaaatcta cacatataga
    18481 agttataaaa atgatttctg atttctcagt cgaaaatgga tttgagattt tagggttaga
    18541 tttttctcct attaaaggtc ctgaaggtaa tatagaatat ctaattcatt tgagaaatgg
    18601 aaatgaagga tatgaatttg atggtgagac atacaataac aaaatagtag aagttgttga
    18661 agcttctcat aatttagaca aataggttaa aagggggctt agatttgatc ctcgaattat
    18721 atatgaaaaa ttgtgcctta gttgaagaac taaggttgaa tattgataaa aacttaaata
    18781 tacttacagg tgaaactggt tcaggaaaat ctataataat agatgcactt ggactttgtt
    18841 taggtgataa atatgatagg tcttttttaa gaaaaggaac agataaggga cttgttgagg
    18901 ctgtattttt ttcagacaat agatatctta aaaaaatatt agaagaaaat gatataagta
    18961 tggaagatga taatttattg gtaataacta ggttgatata ctcagatggt aagagtactg
    19021 ctagagtaaa tggaaggact gttaaagtgt ctcttcttaa agaaattgca tctacactta
    19081 tagatataca tggtcaacat caaaatcaag ctttgtttaa taaagatact catttaaaat
    19141 ttctagacct ttttggagaa aatgaattgg aagagtttaa aattgcttat aaaaaggtgt
    19201 accataagta tagtgaagta aaaaaagctt taaattgctt gacagaaaat aaagatgaga
    19261 tgcaaattca acgagaaata gatttattaa gatttcaaat aaatgaaatt gaagctgcaa
    19321 atctaaataa gaatgaatat gaagatttat taaaacaaag agaagtttat agaaatagtg
    19381 aaaagatata taataatcta aattcgagtt atagcaagtt acataatggt gagtataatg
    19441 ttattgacct aataggtctt gcatctaagg aacttaatga catatctaaa tatgacagtg
    19501 ttttaagtga atatagtgat actgtagaaa gaatcatgta tgagttacaa gacatatctg
    19561 gtgagataag aaattacaaa gataatatag actttgaacc ttatgagcta gagcagattg
    19621 agcttagaat cgacgagatt aataacttaa gaagaaaata tggagacagt atagatgata
    19681 tatttgagta ttatggaaaa attaaagata gattagatga aatattaaac agagatgaaa
    19741 gagttgaaca gttaagaagc aaactgatga atatagaaga agatttaaaa ataaaagcca
    19801 gtaaattgac taaagcaaga atagaagtag caactacttt agaaaaaata cttcttgatg
    19861 aattaaaaag cttaaatatg aaaaatgtaa tgttcaaggt taattttgaa aaaggtccat
    19921 ttactttaga tggagtagat gatattgaat ttatgatatc ttttaactta ggagaagata
    19981 ttaagcctat atataaagtt gcatcaggtg gtgagatgtc cagatttatg ttagcgttta
    20041 aaaccatatt ggctgatata gatgatattg atacattagt gtttgacgag atagatactg
    20101 gaataagtgg gatagcagca cagatagttg gtgagaaatt gagtgatata gcaaagaaaa
    20161 aacagataat atgtataact catttacctc aaattgctgc aaatgcagac actcattatt
    20221 gtatagagaa agatacttca aataatagga cgtttaccaa tgttagtaag ttaaatgaat
    20281 ctcaacgaaa aaatgaaatt gccagactta tagcaggtaa taatataaca gaaaaaacta
    20341 ttgaacatgc aagtgaaatc attgaattgg ctaaaaaatg ttagtgaaaa acaagcattt
    20401 taataggtgt aaagaatttt tatagaaatg ctttacacct attttttata atgaaattat
    20461 tttaaaatat ctagtgccta tattgaagaa aagtaggttt gaaaatggaa taaaatttgt
    20521 ataactttgt aactttgaaa tttctaaatg cttaagtata atattattta ttaaggtagt
    20581 agtgagggga ggcataaaat gaataaaaaa gatactatgc acttaatttt tataattgta
    20641 atttttattt tattatggta tattgtggta gcagtaagtg agattaataa aaatattgaa
    20701 agttgtagta acaaattaga ttatttgtca caagagctta tgagtactaa gtcggatatt
    20761 agtaatacta taaatgaaga aatgtcaaaa agttatataa caaaaagtat tgacttaaaa
    20821 gtaaaaaaaa tcgagaaaaa agaatgtatt attgatgtag atgttcaatt aagtaaactt
    20881 ggaaaaaatg gaaaagtatt ttttatgtat aaagaagata gtgataaatg gaatgaaact
    20941 gagatgacaa aatatggaga attatcatat gcatgtgaaa taaagataaa tacaggaagt
    21001 gaatatgact ataaagtagt tacaagtgga gctatatctg aaagttctga tgtgcaaaaa
    21061 tttactaaat ctgattatat gcctgaacaa cccatattta attctgggat aagagataat
    21121 agagaatact ttattgaaat agtagaaaat agtaatcttt tcaatcatga gagtgaaaag
    21181 tcaaaaaata aagcttacga taatattaga ttagaaaaag tagatattat tgtaaatgaa
    21241 ggaaaaaaag acactatata caaagccaaa ttagctgaag gcttagatga tggcaaaact
    21301 aataattcaa atagaaatca agtgaattat gaagtaagtt ttcctaaaag ggatattgat
    21361 gacataattt atattaaagc taaacttaca tacaataatg gagtagaata tacaaaggat
    21421 ataactgaag atataactat gggattacaa gatttagaaa aataaataca tatttaaata
    21481 aatattcaaa tagatttgtt caataaaata gagtataaat aaaactgtag tagttttact
    21541 tatactctat taaaaaatta taattttaat tccatatatc tagccccttc aattggatta
    21601 taagtataag gttctatatc ataaaaacca aacttttcat ataatccttg tgcacttttc
    21661 atgcttggaa gagtatctaa tctcatgtgt gtatatccaa attttttagc ttcttcaatg
    21721 atttcttcca atagtatttt tcctattttt aatcctctaa attgatttct tacatataat
    21781 ctttttaatt cacatatttt accttcaagt ttttttaaag caacacaacc tgccaaattt
    21841 tcatcaacaa atgccaatat caatgagcct gaaggttttt tatattttcc tggaagtgtt
    21901 tttaattcat tattaaagtc ttgaaaacat aagtctatat ttagagaatt tgaatattca
    21961 gtaaatagaa gttttacatt ttcaaggttt tctaaatctt tttcttcaac aaattgtaaa
    22021 gttatatttt gagccatttt atccgccatt atatacacat gtttatataa tgacttcacc
    22081 tccttgatat atgtatattt ttcttaatat caattagatt ttaataccat tactttttca
    22141 ccaccatagt caagctctcc attaaactca aatccaaaat ctttataaag cttaatagcc
    22201 attttattgt cttcgaatat actaagatat agttcatcac agttatattc atttttaaga
    22261 tgatttacaa gaaaatctaa tgatgctttt ccatatcctt taccttgata ttttgaatca
    22321 atcataaatc tatcaagcca aactctatca tcttctaaac gaccatacat agcaaatcct
    22381 attaaagaat tttcatcata tattccaaca ggtacccaag ctgttataaa tttagattca
    22441 gcaatagaaa gtgcattgct ttctatataa tctaactgac ttttatctac agacaaacta
    22501 actaaatcat gccaattatt tatgtctgca attcttacat ttaatttcaa gatattaccg
    22561 cccttcaaac tttttgttac aatctaatac tatcatatta tgtattaaaa atcacttatt
    22621 aagattttaa ataaactttt taaatgaata aattctcagg aaaaaggaat tataaataca
    22681 taataataca gcataggagt agatggatat atgaacaaaa taaataaaaa tttcaaaaat
    22741 atttggataa tattaggagc tgtatcgatt tttaccatgg ttataatttt taataaaaat
    22801 tgtaatgtta ataaagagac tcaaatagaa gcttttgcaa ttaagaatca tgataaaaaa
    22861 tttgtatatc ctatgggaaa tataattgga gtaaaagcaa atacagatgg tgtattggtc
    22921 ttaggatatg aggaagagga tgtagactat attggaggca tacaaatcgg tgataatata
    22981 gtaaaaatag ataataaaag gataaaaaat agtcaagatg tatcagagat tttgaataag
    23041 attaaaaaaa gtaaagttga agtgactttt gagagaaaaa ataagtataa aacagaagta
    23101 atagagacta aaaaagaaaa tggcaagtat aaacttggat tatgggtaag agataaaata
    23161 tctggaattg gaactatgac tttttacgac cctagtatgg aaaagttcaa agcaatcggt
    23221 catgccataa aagattcgga tactaatgaa ctattaaaga taaagcaagg atatatatat
    23281 aagccagaac aattaaaaat agtaaaagct agtaatgaaa aagtaggtaa aataaaagga
    23341 gattttaatg acagcaattt aatgggtaat ttctcaaata attcagagct aggtataagt
    23401 ggtaatatta cagaaaacca taataaagag tttaatgtag caaataaaga aaagcaatta
    23461 atagaagttg gaaggccgca agatgtaaaa ataggagatg cagtaattct ttttgaggat
    23521 aaaaacaaaa atataacaag ctatgatata aaaatagaaa gtatagtata tgataaagga
    23581 aattatagag atatggtaat aaaagtagta gatgacaagt tattggaata cacaggaggt
    23641 atcgtacagg ggatgagtgg agctccaata atacaaaata ataaaattat tggtgcaata
    23701 actcatgttt ttagagataa tccgaaaaaa ggatatggta tttttataga tgaaatgata
    23761 aaattgtagg tgaggcatta aaaaatttta ttattttatc aattatctag gaggaatata
    23821 attttggagt gtcgaatatg ctttagagta gataattagg aagcaattgt gtaaaaagtt
    23881 tagttttctg taataagaag atgtttttta atggggggat ttttagtgga aaaaatcaaa
    23941 atagttttag cagatgacaa taaggatttt tgtcaggtat taaaagagta tttgtctaat
    24001 gaagatgata tcgatatatt aggcatagct aaggatggaa ttgaagcatt agacttagta
    24061 aaaaagacac aaccggactt attaatacta gatgtaataa tgccacatct agatggatta
    24121 ggtgtaattg aaaaattgaa tactatggat atacctaaaa tgccaaaaat aatagtacta
    24181 tcagcagtag gtcaagataa gataactcaa agcgcaataa atctaggagc agattactac
    24241 atagtaaagc catttgattt tgttgtgttt ataaacagaa ttagagagct agtttctaat
    24301 agagttacac aagttgagcc aaaacctaga ccagttcaag agactcaaat gactagaagt
    24361 gattttgtta agaatgtagg aaatatagag acagaaatca caaatataat acatgaaata
    24421 ggagtaccag ctcatataaa aggatattta tatttaagag aagcaataaa aatggttatt
    24481 gataatgttg agcttttagg tgcagtaaca aaagagttat atccaagtat agctaaaaaa
    24541 ttcaatacaa caccaagtag agttgaaaga gcaataagac atgcaataga ggttgcatgg
    24601 agtagaggaa aagttgacac aataaatcaa ttatttggat atacggtaca caatactaaa
    24661 ggaaaaccaa ctaattcaga atttatagca atgattgctg ataaattaag actagaacat
    24721 agtatggtta aataaacaag acataaaaag taaggctttt taattaaggc attggctata
    24781 aatgcgtatt acaagcagcg aaacggtata accactaggg ttataccgtt tcgctatttt
    24841 aataaatata aaaattttct ttattatttg cttactatat caatataata attttattat
    24901 actatggata tagtatgtgt ctttacaagt tgtaaactga cagtggttta ttttttaata
    24961 taaatattga ctttgatgca ggtaaacttt gtatttttaa gcgtattatg gaatatgtta
    25021 aataaaaaaa tgatgaaata tagtattgta aatgccaaag atgcaaaaca aacttaaaac
    25081 atttatttta ttgttaagta atgctataat ataatgtgat tttaataatg atagtggagg
    25141 tttaaatatg agagtcgagg cccctataaa agtagatcga aaaaccaaaa aacttgctaa
    25201 aagagttgaa agtggggaaa tagcagttat aaatcatata gacatagatg aagttgctgc
    25261 aaactcttta gtagaagcta aaataaaact tgtcataaat gcggctcctt ctataagtgg
    25321 taggtatccc aataaaggtc cagggatatt aactgaaaat aatatactaa taattgataa
    25381 tgttggagaa gagttatttg aagaattaaa agaaggagaa actatagaag ttgtagatgg
    25441 aaagatatat agaaaaggaa aatttttagg tgcaggagaa gttttagaca agtatgaggt
    25501 ttcacaccaa ataaaggctg cctatgagaa tttagctgta gaattggata gatttataga
    25561 taatactata gattatgcta aaaaagaaaa aggatttata cttggagaag tagaaattcc
    25621 aaaagtgaaa actaattatg ctaataaaca tgtattgata gttgtaagag gtcaggacta
    25681 caaagaagat ttaagtacta tgctttctta tatagaagag gtaaagccag tattggttgg
    25741 tgttgatgga ggagcagacg ctttaattga gtttggatat actccagatg tgattgtagg
    25801 tgatatggat agtgtaagtg atgaagcttt aaaaaaggct agtgaaatag tagtacatgc
    25861 ttatacagat ggaagagcac caggtcttaa gagggttgag gaattaggct tagatgcagt
    25921 tgtatttcct gcgccaggaa ctagtgaaga tatagctatg cttatcgcct atgagtataa
    25981 ggctgagtta atagtagcag ttggtacaca ttcaaatatg attgattttc ttgaaaaagg
    26041 aagaaaaggt atggcaagta cttttttagt tagactaaaa ataggttcaa agcttataga
    26101 tgctaaaggc gttaatttgt tatacagaag taaattaaaa ataaagtaca tatgggcatt
    26161 aatagcaaca gcattatttc ctgtgttggt agttgcatca ttgtcaccag gagttcaaca
    26221 gttcatacaa ctaatgcaat taaagtttag agtattatta cagatgtaaa ttttaggagg
    26281 ataaatatgc atattaatat gaaatattat atagtcacta taggggctat atttatagct
    26341 ttgggtatag gcatgttagt aggatttaat ttaaataata atcaacaatt aagtgaacaa
    26401 caagcaaata taataaatga tttggatgat aagtttgata tcttaaaaga aaaaaatgat
    26461 aaacttgaca gtgacttagc aagtgtaaat agagattatg aagaggcagt taattttata
    26521 aataaaaatg tagataagat tttagctggt tcgctgaatg gtaaaagtat aggaataata
    26581 tctgctaatg aaaatgacga ttatacaaaa aatatagaag acataataaa taaatctaat
    26641 ggaagcattg catttaatat aatattaaaa gaaaacataa caaatccaga aaagttaaag
    26701 gaaatgtcaa ctaaactagg tacagatgta aaaaatgcaa atgatgcagt taattatata
    26761 attgacactc ttaaaaagga agatgcaagt gacattttaa catatcttca agaactagat
    26821 gtaataaagt ttaattttat tggagataca tatctaaaat atgattccgt tgtaatagct
    26881 ggtggaaatg atgcaaaaga cagtacaaaa cagtttgaaa aaatagaaaa atttgtagtt
    26941 tcaaaactta aatcagagaa taaatattta gtagaagttc aaaatacagg agttaaaact
    27001 tcttatgtag aactatattc taaaaacaaa gttgcaacta tagacaatat tgatgaaggt
    27061 ataggaagta tatctctagc gattcttcta caacaaggta atatagttgg taattttggt
    27121 agattggata ctgcaacttc attgttgcca tctattaaat agaaataatt ttaaggagag
    27181 aaaaaatgga ttcttatata agtataataa taccagctta taatgaagaa agtagaataa
    27241 aatatacatt agaaagcata ttggacatta agcaaataaa tgaaataata gttgtggatg
    27301 atggttcaat tgacaatact gctaaggttg tatctgagct agaaaatgaa aagattaaat
    27361 tttttaagtt agataaaaat agaggtaaag gatatgcttt aaattatggt atcaaattag
    27421 caatgaaaaa tgcagatatt ataggttttc tggatggaga tttaggaagt tctgctaaag
    27481 aagttgaaaa attaatagta cctatattaa atggtgaggc agatgttaca atagccaagt
    27541 ttcctcctgc aaagagaaaa ggaggtttgg gatttgtaaa aggtttagct aaaaattctg
    27601 tgtttgagat gactggtgtt gagttagatg caactttgtc aggtcaaaga atatttaaaa
    27661 gagaagtttt agaaaagttt gatgaaatac cttttggata tggagtagaa gttggaatga
    27721 ccattgatat attaaagtat ggatttaaaa ttaaagaagt attagtaaat atgactcata
    27781 atgaaacagg aagaaattta aaaggtttta ttcatagagg gaaacagtat tatcacataa
    27841 aaaaggtttt aggacaaaaa aagaaagaat ggaggtaata tcttagtgaa agattatata
    27901 ctttatacca ttttattatt aactggatta tttggaacct atgctgtaat tccactattt
    27961 aaaaatttat tgataaatgg aaatgtactt agaccaaact ataaaaaaga tatgatacca
    28021 gtaagtatgg gaattgtatt tttgcctatg attgtaatca atggaataat acttgctttc
    28081 tttactacag aatttaagga tttagcgtat atatttatgt ttatgtttgg tatgatatcc
    28141 atgttttttg cagggatact agatgatgtc attggaaata gagatgtaag tggtttaaag
    28201 gggcatttta aaagtttatt taaaggaagt cttacaacag gaggttttaa agctttattt
    28261 ggtggatttg tagggcttat agtttctgtt gctatatcaa aagacataat tgatataata
    28321 gtaaatacac taataatagc tctatcaact aatttaatga atcttttgga tttaagacca
    28381 ggaagggcaa taaaagcata tttattcata atggtaatta tatttttaac attgacagga
    28441 tttgttcaag ttcttccatt acttatagta ccaaatgtac ttgcatactt taattatgat
    28501 ttaaaagcaa gggctatgat gggagatact ggttcaaacg tccttggaat atctattgga
    28561 atgctcattt cttttgggta tccatttaac attagattag gatggttaat atttgtagtt
    28621 attatgcata tattcactga gaaatactca ttaactaaga taatagaaaa aaataaacta
    28681 ttaaatttta tagataaatt gggaaggtag tattatgata agcaaaagag tggggattgt
    28741 tgaatcaata gtaagtcaaa ctgaaactct agatgatata agagtaaata taaatggaga
    28801 aatacaaagg gcatataatt atcccaaaat atctggaact ataaatatag gtgacgaagt
    28861 ggttttaaat acaacagcag tagaactgag cttaggtaca ggtggatacc attttgtaat
    28921 aactaattta aataatatag aatctacttt aactgaaggt ggacatataa tgaaacttag
    28981 atatacgcct cttcaaataa aagtggattc tgttgaggaa caagaaagta tttatcatga
    29041 taaatttgcg aattttaaag gattagaagg tctttctgtt gtagtaggga ctcttcatag
    29101 tatgttaact ccatttgcag cttcatttaa aagaaataat ccaaataaaa aattagtgta
    29161 tataatgact gatggagcat ctcttccaat ttatttaagt aaaaatgtgg atactttaaa
    29221 agaaaaaaaa ttaatagata gtacaataac tataggaaat gcgtttggtg gagattatga
    29281 atgtataaat atatatactg cattaattac agcaaaagaa atactaaaag cggatgcagt
    29341 atttgtcagt atgggacctg gaattgctgg gacaggaaca aaatatggat ttacagggat
    29401 tgaacaaggc tctattcttg atgccgtaaa aaaacttgaa ggaagagcaa ttgcaattcc
    29461 aagaattagt tttgctgaca aacgagaaag acatcaaggt atttcacatc atagtatgac
    29521 tgtatttaaa gaaattgtaa atgtaaatgt agacatacca ataactatat atgatgatga
    29581 aaaattgaac tttataaaag agcaaatcaa tttaaatggt ttagacaaaa agcataatat
    29641 aatttatata gataataata aaacgaaaga ggatttagac tattttaatc taaaagtaaa
    29701 gagtatggga agaaattatg aacaagatga ggcatttttc aaagctgcaa gcacagcagc
    29761 atattactta atggaggttt aagatggtat tagaagaaaa aactattagt agtgataggg
    29821 tttatacagg taaagtaatt actttaaagg ttgatactgt tgaaattcca gggcaaggat
    29881 atcaaaaaag ggagttagta gaagttggtg gagcagtagg aatagttgca atcacagatg
    29941 ataataaagt tgtgttagtt aagcaattta gaaaacctat agaaaagcca atctttgaaa
    30001 ttccagctgg taaactagaa aaaaatgaaa gtccaaaaga atgtgctgaa agagaattaa
    30061 aagaagaaac tgggtatagt gcaaaaaata ttaagctaat acataaattt ttcacttcag
    30121 caggtttttc taatgagata atgtttgtat atttagcaac aggtcttact ccaggagaga
    30181 ataatttaga tgcagatgag tttttagatg tctatgaaat tgagcttgaa gaagcatata
    30241 acatggtatt aaaaaatgac gttgaagatg caaaaacatc tattggatta ttattagtaa
    30301 aagatatgtt taaaaattaa tatttataaa atgaataacc ctttgtccta aagcatacta
    30361 ttttataaag gacaaggggg aattaaattg agaagaacat atagaaaaaa tgattttaga
    30421 gaattaaata gacaaataat tattatagga ttgttgttta tgatgtctat tgttattggg
    30481 tcttacataa ataaaatatt gccaggttct agtaacaata tattaaacaa tataaatcct
    30541 gctgtagagt attataatct aaatataagc ataaaagata cagtgataca aaatttaaaa
    30601 tcagatgcaa tctttatggg ctcaatagct ctattaagtc tatttgtagt aacaattcca
    30661 gcagtgttgg tagcttttgt attaaaaggg atgtcaattg gttatacaat aaatagctgt
    30721 atattggcat taaaatttaa aagtataaaa atgattttaa taatattatt taaaaatttg
    30781 attattattc catgtgcaat catattagca ttaattagtt taagttattt taaagaaatg
    30841 gtttatgaat ttaaaaagaa aaatagaaaa aatatgcaat ttttaattaa gaggtatata
    30901 ctaaatatta taattataat agcactatca ttggggttgc aattaatatt aaatactgca
    30961 agtattggta ttattaagtt cctagctaaa taaaggagtt tataatggat attatagagg
    31021 gatatataga ttacataaaa gataaaaaaa aattatcaga gaatacagtg gcatcatact
    31081 ttatggatat aaaaaaatat atggaatata taaatcaaaa aagcattaaa ctagtagata
    31141 tagtagaaaa tgatattata agttacttaa taaagttgga aaaagataat gtatcaatag
    31201 ctacaatagc gaggatgata tcctctataa aatcttttca tgattattta tttttaaatc
    31261 atatatgtgc aaataatcct gcaaaggata taaaaaaacc taaaataaaa aaagaaaata
    31321 taaatatact tacagaagaa gaaattgaaa gactattaaa ttttccaaag ttaacaacgc
    31381 ctaaattgat tagggacaag gctatttttg aagtattata tggtactggt ataaaagtat
    31441 ctgaattagt agagatgaat atagaggata ttgacctaga tattgattat atatattgta
    31501 attcatgttg taaaaatcaa agagtgatac cactttgtga tattacaaaa ctttacttag
    31561 aaaagtatct aaaagaagca agacctaaaa tggctgtaga aggtgaaaaa tcattattcg
    31621 taagttcatt aggtcaaagg tttacacgac aaggtctttg gaaagtcata aaaaaatatt
    31681 ctaatctagc caatatagat aaaaatataa atcctacaat gcttagacat tcatttgcta
    31741 ttcatttgtt aaatgaaggt gctaacattg ctgttgtaag taaaatttta ggaaatgtta
    31801 atttatctag tttgcaagta tatttaaatc atatagataa aaacgtgaga agagaaataa
    31861 aggagaaaca tcctagaaat gatgttgatg tagaattaca aaaagcagaa gctaaataga
    31921 ctatatagca aattttataa tttagaagga gcatatttat atgagcagag taatttggat
    31981 tgtaattgat agtgttggga taggagcatt gcctgatgct gaaaaatttg gtgatagtaa
    32041 ggatgtaagt acccttggaa atatatttaa ggaatatcca gatattcaga ttcctaatat
    32101 gagaaattta ggtataggaa acatagatgg tatagatttt tttgaaagta taaaagaacc
    32161 aataggttgt tttggaaagt gtaaggaaat gtctcaggga aaagatacta ctacaggtca
    32221 ttgggaaatg actggtataa tagttgacaa accatttaag acatttgaac atggattctc
    32281 taaggagata atagaagagt ttgagaaaaa aactggaaga aaagtagtag gaaataaacc
    32341 agcttcagga actgtaataa tagatgagta tggagagcat caaataaaaa ctggagatgt
    32401 aatagtatat acatcagctg atagtgtatt tcagattgct gctaatgaag aagtaattcc
    32461 cctagaagaa ctctataata tgtgcaaaat cgctagggaa ataatgatgg gggataatgc
    32521 agtagctaga gtaattgcta gaccattcat aggtaagaaa aaaggtgagt ttgtgaggac
    32581 ttcaaataga agagattatt cactagaccc atttgaacca acagttcttg ataatataaa
    32641 agaatcagga cttgatgttt tagcagttgg aaaaatagaa gatattttta atggaaaagg
    32701 aattacagat gctatccaca ctaaaagcaa tatggatgga gtggatgaaa ctttaaatta
    32761 tatgaaacaa gataataaag gtctaatata ttcaaatctc gttgattttg attctaaata
    32821 tggtcatagg agagacccag aaggatataa gaaagctctt gaagagtttg atagtagact
    32881 tcctgaaata atggctaata tgagagaaga tgatatttta ataatcaatg cagaccatgg
    32941 aaatgaccca acatataaag gtacagacca tacaagagaa tatatacctg ttatgattta
    33001 tggcaataag attaaaaaag gttttaattt aggagtaaaa gatacttttg ctgatattgg
    33061 agcaactgtt gcagatatac taaatgtaaa gttgcctaaa catgggtcaa gctttaaaga
    33121 agatttattt taaactataa aatgataaaa acttagctta ataggatgga gagattggaa
    33181 tgtttgaaaa gatagcacaa agtagtaaat ttataaattc taaaagtaat ataaaaccta
    33241 agattggttt gatattaggt tctggactag gtgatttagc aaatgatata gaagaccctg
    33301 tcacaattaa atatagtgaa attccaaact tccctgtatc aacagtagca ggacatgctg
    33361 gacaacttgt aattggaaaa cttgaaggaa aagaagttat tgctatgcaa ggtagatttc
    33421 attactatga aggatattct cagaaagaag ctacttttcc agtaagggtt atgaaagaat
    33481 taggagtcga gattcttata gtaactaacg ctgctggagg cgtaaataaa gaatttaaag
    33541 caggagattt gatgcttata agagaccata taaactttag tggaagtaat ccattagtag
    33601 gaaaaaatga tgacagattt ggtgctagat ttccagatat gtcagatgca tattcttcta
    33661 aatatgtaga tgtagttaaa aactgcgcta aagaatgtaa tatagatgtc aaagaaggcg
    33721 tttatatgtt ttttagtggt ccaaactatg aaacaccagc agaagtgaga atggcacaaa
    33781 ttttgggagc tgatgctgta ggtatgtcta ctgttccaga agtcatagtg gcttctcact
    33841 ctaatatagg agttattggt atatcttgta taacaaatat ggctgctggc atcttaaatc
    33901 aaccactaag tcatgaggaa gtaatagaaa ctactcaaaa agttaaatca gaatttatga
    33961 atttagttaa aacaacggtt aaaaatttat aagttaaagc ttattataga ttttttgagg
    34021 aagtttataa taaaatagtt aatgtttaat ttgaaaagaa ttaataaaaa gctgtcttga
    34081 tatagaaagt tatttctaat aaaggacagt ttttttataa tactacaaca tttgaaagtg
    34141 ttttaaagtt taatatttat ttaaattatt ataggttaga atggagattt caattatgag
    34201 aatgtatgat attataaaaa aaaagagaga taacctagag cttagtaaaa aagagataaa
    34261 ctactttata gaaaactatt caaagggaga tatacctgac tatcaagctt ctgcactatt
    34321 aatgtcgatt tacttaaata agatgaataa acaggaaact gtacatctta cagaagcaat
    34381 gatgaactct ggagacatga taaacctatc tgagatagat ggaataaagg tagataagca
    34441 tagtactggt ggtgttggag ataagactac catagctctt atacctttgg ttgcttcatg
    34501 tggagcacca gttgcaaaga tgtcaggtag aggtcttggt catactggtg gtactattga
    34561 taaattggag tctataccag gtttttcgac agaaatggag ataagtaaat ttattgattc
    34621 tgtaaataag tctaaaatag cagtttgtgg tcaaagtgca aaggtagcaa ttgcagataa
    34681 gaaaatatat gctcttagag atgttacagc aactgttgat aatatatcat tgatatcatc
    34741 aagtgtaatg tctaaaaagt tagcttcagg agctgatgca attgtgctag atgtaaaaac
    34801 tggtgatgga gcatttatga agacattaga agagtctttt gagttagcta aatctatggt
    34861 tgatataggt actggtatga atagagatac aatagggatt gtaacagata tggatgaacc
    34921 tttaggtttt gcagtgggaa actctttaga agttatagag gcaattgaga cattaaaagg
    34981 aaatggacct aaagaccttg ttgagctatg cgaagtatta ggagcatata tgttggtttt
    35041 atcaaaggta gcacatgatt ttgaagatgg tgttgaaaaa ataagagaat caataaaatc
    35101 tggtactgct atacaaaaac tcaaagagtt tatagagaat caaggtggta ataaagatgt
    35161 agtagatgat tattctttat tcaaaaaatc aaagtataaa tatccagtta aatcaactaa
    35221 atcaggttat ataagcaaaa ttaaagctga agatgttggt gtatcggcta tgattcttgg
    35281 agcaggtaga gaaactaaag atgatatttt agatttatca gcagggataa ttttagaaaa
    35341 gaaagtagga gattatgtaa atgaaggtga agttttagct tacatgtatt ataatgatga
    35401 acaaaagctt tcattggcaa agggaagatt tattgattcc tactctattg tagattcaaa
    35461 aatagaaaaa aataaattaa tatatggtat tgtaactaaa gaagagatta aaaagtttta
    35521 gaaaagtgat tataaaaggc ctaacatgtc aaaaataatg ttaggttttt tattttttga
    35581 taaactataa attataccaa aaatatatat tttaaaacat tttttacaat ataaataagt
    35641 ttattctaca agatgattga aaattaaagt atctagtttt ataatagaaa atggataaat
    35701 atacataagg agtagattat attatgaact ttaaagaaaa tagattgaaa atagcagtat
    35761 taataattgt tattttgatt atcttagcag gtatatttgt gtttatacaa ataggtcctt
    35821 atgataaaaa taacaaaaaa gatgtaatta tcgacgttcc aagtggagca tctgttggaa
    35881 aaatatctga catattatat gaaaataaat taataaagaa tgaactatta tttaaacttt
    35941 tggtaaaggt tagcaataaa gctccgtcta taaaatcagg aacatactta cttaatcaat
    36001 cgtattcaaa caatgatata ataagtcttt tagtttcagg taaaatatat caggatggta
    36061 taaaagtgac tattccagag ggagctacat ctaaagaaat tatagcaatg ttagtaagta
    36121 aaaatttagg agataaagct acttttgaaa atttaataaa aaaacctcaa gaattttatg
    36181 ataaatttcc atatttgaag gaagatggaa taacctcttt agaagggttc ttgtatccag
    36241 aaacttatta ttttaattca aagaaacaat cagaagaaga tattttaagc gaaatgttaa
    36301 aagtatttga cagtaaatac acggacaagt ttaaaaagaa acaaaaagaa ttaaatatga
    36361 ctcttcaaga agtaatggaa atggcatcaa taattgagaa agaagctgtt cttgacaaag
    36421 acagacctat aatagcaagt gtgttttata atagacttaa ggtaggtatg cctcttcaat
    36481 cagatgctac aatacaatat atatttgaag agagaaagaa aattgtaaca tatgatgatt
    36541 taaaaattga ttcaccatat aatagttata aaaataaggg attacctcct acaccaatat
    36601 caaatcctgg tataaaatct attgaagcag cattatatcc agagaaaaca gactatttat
    36661 attttgtagc taagattgat ggtggaaata attatagtac aaactatcaa gaccatttaa
    36721 aatacgttaa agaatataaa gaagcaaggg ataaacaatc aaaagataca aaagcaacaa
    36781 ataaagaaaa tacaaaaaaa taaaccatga ttataaaaag tctaacaggg taagaataat
    36841 gttgggcttt tttattgaaa attgttattc ttagatttat aataaagaaa gtgtaaatat
    36901 atataacaat atgaatttaa aaaataataa attaatataa aacttgaata tttattattt
    36961 tagggagtgt ttttatgagt aatatagtta atgatttggt tgaagattat ataagagtga
    37021 cattaaaaga aaaagaagga tttttaaaag atttagaaat ttatgcagag gaaaatagtg
    37081 ttcctataat acataaagaa gtttcagatt tattaaaagt cttgttaaag gttcaaaaac
    37141 caaagagaat tttagaagta ggatgtgcaa ttggttattc ttctattttt tttgcaacta
    37201 ttataggaaa agatgcagat ataataactg ttgagagaaa tgaaaaaatg atagaaaaag
    37261 caaaagaaaa cataaaatta gctggatttg acaataacat aactatacta gaaggagatg
    37321 cagaagaaaa acttagtcaa gtccaaggtg aatttgacct tatatttata gatgcagcca
    37381 aaggtcaata taagctattt tttgatttag ttatagataa attaaaagat gggggacttt
    37441 tagtatctga taatattttg tataaaggta tggttgctca tgatgatttt gttgtaagaa
    37501 gaaaaaagac tatagttaaa agaatgagaa attatttaga ttatatatgt aattgtgact
    37561 atttaagcac atcattggta ccaataggtg atggtgtagc actaagttat aaagaaagta
    37621 aaagaggtga tgtagatgga attaaataaa gtagaacttt tagctccagc aggtgatttg
    37681 gagagattga aaatagctat aacatatgga gcagatgccg tttatatagg tggagaaatt
    37741 tttggaatga ggtctgcagc gaagaatttt agtaaggaag atatggcaga gggagtagct
    37801 tttgcacatg aaagaggcaa gaaagtattc gtaacagtaa atataatacc tcataatgaa
    37861 gattttctac aattagaaga ctatttgttg gaactagaag agataggaat agatgcagtt
    37921 ataatagctg acccaggagt gcttagtgtc attaaaaaag taattccgaa tatggaaata
    37981 catttaagta cacaagcaaa tacaaccaat tatctaagtg caaacttctg gtacgagcat
    38041 ggaataaaaa gagttgtagt ggcaagagaa ttatcttttg atgaaatatc tgagataaga
    38101 gcaaaaacac ctttagatat ggatatagaa gcgtttatgc atggtgctat gtgtatttct
    38161 tattctggca gatgtttaat aagcaactat atgactggaa gagatgcaaa caaaggttct
    38221 tgtgctcaat cttgtagatg gcaatatcat ttggtggaag aaaaaagacc tggtgagtat
    38281 tttccaatat acgaagatga aaggggtaca ttcttcttta actcaaaaga tttatgtatg
    38341 atagagtata taccagagtt aatcaaatct ggtataacaa gtttaaaaat agaaggtaga
    38401 atgaagactg catactatgt agctactgtt gtaagagcat acagaatggc aatagatgaa
    38461 ttttacagag acccagaaaa ctggaagttc aatccaatgt ggatggaaga actaaaaaaa
    38521 ggtagtcata gacattttac atcaggtttt tacttgaata aaccaacaac agaagaccaa
    38581 aattatcaat cagcatcata tgttagaaac tatgatttta taggtatagt tagagaaaca
    38641 gaagatgaag atggtcttat tgttgttgag caaagaaata aaatgtgtgt tggtgatgaa
    38701 atagaagtta tgggaccata taaagaaact atgtttacta aaattgaaga aatgtacaat
    38761 gaagaaggag aagctataga atcagctcct catcctagac aaatagtgaa gttaaaacta
    38821 tcagtaaaag ttggtaaaga ttatatgctt agaaaagtta tagaagaaaa ggttgaagaa
    38881 taataaaaaa ttgataaaaa tagtattagc cccttagaaa ttgtcaataa tgaaattatc
    38941 taaggggtga tttcatgtca aaaaagaaga ctccattttt gaaaaaagtg ggaaagagaa
    39001 gctggtgtat atttactata attttaataa tttatagtgt tttaatttat aggctagttg
    39061 atatacaagt attaaaaggt gataaataca aacaaagtgt tgaatcacaa agcgttgaga
    39121 aagtcgagtt aaatagtgga agaggaataa tctatgatag aaacaacaag aagcttacag
    39181 atacaagtaa atctcagata ttaattgttg aaaaagaaaa attaaataat aactataaaa
    39241 ttttggaact tattaagaaa gctactaaga tgaatgattt agatatatat aaagctgtac
    39301 aagagcaatt gacacgccct ataatacaga ttcagactaa aaatatcgat aagagtatga
    39361 aaaaagaact tgagaaaaat ggaataatgg tagaagaaaa aactatgagg tacgcaaaag
    39421 atggtttatt atcacataca ataggatata taaaagaaga tgataaatca ggtcaatcag
    39481 gaattgaaaa gagtatggat agtgtactta gaaattcaaa tgaaaagtat ataagtgctt
    39541 ttaaagctgg agatgcagga aatgaaaaat ctctaaacat actaaaggga agtgtaaaaa
    39601 ctgttgataa taaggataaa gatagacatc taaaaactac tattgattat aacattcaaa
    39661 aaaaattaga acaaatacta aataaagaag aaaatcctac agcagcaata atctcggaag
    39721 catctacagg tgaaattctt gcaatgtgct ctagacctaa ttttgaccaa aatgacatat
    39781 caaaaagttt aaaaggaaaa aatggagaat ttgaaaatag agttataaaa gcgacatatc
    39841 caccagggtc tgtatttaag atggtagttt tattttctgc acttgaaaat ggtgttatag
    39901 atgagaacta tacttacaac tgtacaggta agactaaagt tgggaatact aatgaaatac
    39961 tgcgatgtaa taaaagagat ggtcatggtt ttcaaaactt aagacaagct ttttctaatt
    40021 catgcaatcc tgcattttta gatatagcta tgaaacttgg aaaagaaaag atactcaaat
    40081 ctgctgaaaa attacattta tttgaaaagg ttgatattgg tcttgatgaa gaaaaaatta
    40141 gagaagctcc aaaaaacata tcaataagaa atttagctat aggtcaagaa aatatagaat
    40201 ttacaccact tcaaataaat caaatgactc aaataatagc taataatgga acattcaaac
    40261 cactatactt atataaaagt cttgtggaca ataatatgaa tacaataaaa acttataagt
    40321 cttcaaaaaa agaagaactt atttctcctt atgtgtgtac acaagttaaa gaatatatga
    40381 agtctgtatc taggactggt acagctaaag acctaaaaga tattgaaggt ggttgtggag
    40441 ttaaaactgg tacagctcaa agtagtttaa ataaaaaagc tatagaccac ggatggataa
    40501 caggatttta tcctgaagaa agacctaagt atgtaataac tgtgttagta gaaggaactc
    40561 aaaaaggaaa taaatctgca acacctatat ttaaggaaat atgtgaaagt ataaaataaa
    40621 ttatgtacta taaaatttaa ggatatatcg taactttgat tttagataga aaattttgtc
    40681 taatgatgta cgatatatcc ttttaaaata tagtattaac tttcttgaac aagctctttt
    40741 tctagttttt taagagcttt tttttcgatt ctagatacat atgaccttga tatatcgagt
    40801 ttttgtgcaa tttctctttg tgtcttatag ccataaggag ttaacccata tcttaactgg
    40861 acaatttctc tttctctagg agtaagaatt ttgtttagtt gttcgtaaag ttttccaact
    40921 tgaactttta gttcaacttc atcaagaaca tagttagcct ctgtaccaag tatatctaaa
    40981 agacttattt cattacatac tactctttat atgttattgg tattactggt cttcatgtaa
    41041 tttcaaatgg accattaatt caaaagaatc tagtttttgt tctttagact tataataaac
    41101 tgctttatca attacagatt ttagaagttt attttttcca agggaatctg aatcatggta
    41161 aagtgataac acagttttaa tatcttctat tattttagaa ttgtcttttt taacagtatt
    41221 caatctattt tttactgtct taattgaatc tttaatttct tcagttcttg aacttatatt
    41281 gttggacctt tcaataaatg tatcttcatc atatattcct cgttctagta aatcatataa
    41341 cttatttttt tgcttgccta attcttttaa ttcagtttct aagcccttta agactcgttt
    41401 ttgaaattct atattactat ctttattatt tttatctaag tctatatcag atgcttttaa
    41461 ttgatatttt tttacagtgt cttccaaaga ttttaaaatg gcagcttcaa taaattcaaa
    41521 tcgagaactt ttattgcaac caggatgata acaaattata tagtcatggt ctgcatatgg
    41581 tctatatact aatggtctac cacaattttt gcaaatcact attcctgcaa gtggattttt
    41641 tatttgatta ccatagctga catgaccatt ttttttgagt atattttgag cttttttcca
    41701 tgttatttca cttattaaag gttcatgctt tccttttgcc tcaatccatt catctttagg
    41761 tcttagttta actgttttta ttttatttgg atttttagat tttttgtagt cctttttttg
    41821 ccactgaatg tagccacaat ataccttatt ttttattata tttgtaattg cagaattgta
    41881 ccaattagca cctgtagcag ttttaatgcc taagttattt aggtattttg atattttact
    41941 acaacccata tcttcattaa tatataagtc aaagatagtc ctaactacat cagcatcttt
    42001 atttggtaca agtattcttt cttttctacc agttgttaca gcatcatatc caaatggagc
    42061 agaggttcct atgaaattcc cttcttcaac tgattttatt ctacctcttt gcatccttct
    42121 tgatataagt tttaattctt ttcttgccat aaatgcttca aattctgaat actcctcatc
    42181 aaattcatct gttaggtcgt atgtttttct aggtgtgata attttggtct tactttcttt
    42241 gaatgtttct aatatgatac cttggtcttt catgtctcca cgaccaagtc tgtctaagtc
    42301 cattactaag actgcatcat atttattttc ttcaacttct tttagaagtt caagcatttt
    42361 gggtctatgt attatacttt caccagaaac taattcttct tttatctcaa ttacatctaa
    42421 gttttgttct ttggctagtt ttagtagggt tgatttatgt ctacttaaag tttcaaattc
    42481 gccttgtttt tctgcctctt catcagcacg ggattttctt aagtatatgg caacactcat
    42541 aataagtaat cacactcctt atgcactatt atatagtaaa tcaatagagt ttaaaatata
    42601 gaaaataagc atgtcaaaag ttaatttaac tttcaacata cttattttct ataatattaa
    42661 tgccttataa tcctttaata tcatttagat tagtttttgc atattcatta tctgggttaa
    42721 gttcaagcgc cttattgtaa gattctctag ctttattaaa ttctgattta ctcataaaaa
    42781 taacacctct taaattgtaa gcatcactag cgtctatttt ataagcttca ttatttttat
    42841 ctagatattc taagtattta tcaattgact ttaaagcctc atcatatcgt tgtaactcta
    42901 tataaatata tgattgtgta taatatgcaa gtggattttt atcatcaatt tctatagctt
    42961 ttttgatatc aatagcagct ttattataat ccttatcttc atctttttct gtttctgacc
    43021 tagcgatttt gacataatta gagctaagag ctcttttaaa gtctttatgc cataataatt
    43081 tatattcatt atcttcgatt ataaaatatc tatcaaaatt tgcagtatct tctttatttt
    43141 cagtgatata ctttatagta tcagtttctt ttattttaac aagatttgtg tactctttat
    43201 tagaatattt gtatttctct actttatttt cttcaccaag tttataatct tttagggttt
    43261 gaagtttaaa taaagtatct tgatattctt caaatttttc tagactgaca ctttccttac
    43321 tgtctttact taataaatta tatgctactt cgtagtcttt gatttctata ctatcaaggt
    43381 actttttagc tacttctgta gcactttctt ttggagcaca tccaaccatt gatatcataa
    43441 ttaaaaatga tactaatatt gctgttattt ttttactgat tatcataata taatccccct
    43501 tatattgtct ctcattaatt ttattttatc accatattct accaaagtca ttaatttaag
    43561 agtgatattt ttcattaata ttatattaag taataataac tttttaaatt tatggtaaaa
    43621 ttttcctgaa aagtattata taatttaggt gaaaatattt aagagaagga gatattatga
    43681 aaattaaaaa attattaata atagggttat ctttatctat atttattgct agttgcccta
    43741 tatctgcaaa tgctcttgat aaaattgaat caattaaagg tgcagataaa tacgaaactg
    43801 ctggtataat tgcagacaaa caaaactata ctacagctat attaattaat gcagacagta
    43861 caatggctga tggattaagt gcaagtggac ttgcaggagc tataaacgct ccaattcttt
    43921 tgactaagaa aaataacata ccaaatgcta cacttaaaag attagaaaag gcaaaaaaag
    43981 tatatataat tggaggagaa aactctattg ataaatatac tgaaactgtt ctaaaaggca
    44041 aaggaataga gattaaaaga cttcaaggta gtgatagaat taagacaagc tataatgtcg
    44101 caaaagaaat aaactcaatt aacaaagtaa ataaagtcat attgactaat gcatttaaag
    44161 gagagcctga tgcaatgagt gctgcacctg tagcagttag agataaagca gctatagtat
    44221 taactgatgg aaaaagtgtt ccatttaata caactggtgt agaaagttat gtaataggtg
    44281 gtacttcatc aatgaatgac aaaatagtta aggatactaa ttcaactaga ttaggtggga
    44341 cagatagata tgatactaac aaaaagataa taaataaatt ttatagtgga gtaaaagaat
    44401 tttatatagc aagtggtact gatttagtgt atgctcttgt tggttctact gttgctaaaa
    44461 ataatgctat tgtgttagtt gataatgata gtaataaaag tgtattgaaa agtacaatta
    44521 aattaactgc tataggaaat ttgagtgata gtatattaca gcagtgttta aatgtaacaa
    44581 aaaatatagg agattctaat actggaagag aatatacagt agaagatgct gctaatgcag
    44641 tgaaaaaact attaggtgtg aagaaatttt attacgaacc taattattca gaagatgaag
    44701 atttaatatt tctactagat aaaaattttg atttttcagg aaaagagtac tatgtatttg
    44761 cttacattaa acagggtgca gagggtgatg ttagatactg tgtagctaaa aatgatatga
    44821 gcaaagttta tacatatgat gttaatggta atatgaaagt atgtaatcca gatgattata
    44881 aaaataaagg aagtataaca gaggaacaag caaaacagat agcattaaaa gaatgtgcta
    44941 agagacataa agtcagtatc aataacttag tagttgatat gatagatttt agagatgata
    45001 tatatagtgg taatgtctat gctgttaaaa tcaattcaaa aaatagtaat ggtacttttg
    45061 gttggttttt tatagatata gaaactggga aagtttataa ttaaaattag aacttttaaa
    45121 caagtgtttt taattatata atttaccata atatgttata atatttttag caagaagatt
    45181 taacttacaa tctatagagt ggagttcatg tacaaaagat tatcctccca acgattcgaa
    45241 gggaggtgag ttcatggata actttttgtt taatgtttta gctagtttaa cagctagtgt
    45301 ggtagtttac ttaatcagta aactattcaa aaaagcaaaa agccactctc gcacaaagag
    45361 tgacttacga gttgaattta aatttatatt taaatccaaa aaataaactc tgtttatgat
    45421 gaactccact ctaacgcaaa atagattgta gttcttcttg cttttattat atcacaaatt
    45481 agtacagata ttcaaaaata atattttttt tgatataata aaaatgtaga gattttgcag
    45541 tgagcgatat ttttgataaa atagggctta acagttgaga tatgaggcat tgagggtatg
    45601 tgataaatct tatcaattgc actactcatg gttcactgca aatttgagag agttgtatat
    45661 gtgtagatat tgaaaatact tagtttattt tgaggtttta tattaactat gtggtatgta
    45721 aataccttaa aatcgtcaga tatataacct ttttctttat gttttatatt aactatgtgg
    45781 tatgtaaatt ttatattaat aaaatcattt acatttaaac tcaacagttt tatattaact
    45841 atatggtatg taaatgacca agatacttga aaaaatatcg ctgactattt tgagttttat
    45901 attaactatg tggacaagaa tagagtagtt tgaactactc tattttttat ttaaaagtat
    45961 attttacatt aattttcttt ttcttaattc ttcttcacaa taatatcgac acaattctaa
    46021 aaaatctatt tctaaagcaa gtgataaatc tatgattgta gaaatattaa tatttttgta
    46081 tctcttattt tccaaatcag aaatatatgc tctactataa ttcgcttttt ctgctaattc
    46141 gttttgagtc atacctcttt cttttcttag tttttttagc atatataaaa tctcctttta
    46201 ttaaatttta tataagataa tatttgtaga attataaaat atatgatgtt attagcgtca
    46261 ttattttatg gaaatttatg gtagaattag ttaagaatat taagaaaatt tattttgaag
    46321 gtctataaat accgaccaaa taatttgtaa attatatgta aaaataatgc aaaaaattgt
    46381 aagaaaaaaa tcaaaaataa aatgatttat ttttagaaaa tcatgtttag tcatttttag
    46441 cgttatataa cattaatgtt tattaacgag tattaaatag tactagttta tttaaaatca
    46501 aaactaaaat gaagaggtgt agagtttttt tgtgggttgc aggaattttt ggaagtctat
    46561 ataatatatt tacaaagtaa ttcttagaaa ttttaaatag agtatttact ggaataaatt
    46621 taccagagtt ataaattaag gggattttca tacctatttc tacgaacata agttcttaaa
    46681 atcttaatat ttcttaattt tagataaaaa taggagatat aaaacgttta aagaatacaa
    46741 gagaataaag aataaatata taaggagatg cttcaaatga aaatataaat aatgtactaa
    46801 atttatacaa ataaggaaat aatatatagt gtatttaaaa ataaaaagac tggtggtgtt
    46861 taatattagg tgtatttaaa taattattta caatattagg ggtaatataa aatatttatg
    46921 agttggagga atgtagcaat ggatgaaatg ggaaaaaata aaataattac tataaatttg
    46981 gaagacgaaa ttaaaagttt agatttagat atatttataa agtatataga aatttttaag
    47041 aaaaaagaca atgatagttt tttaaaaact ttagattata tgaaatattc aattaaaaaa
    47101 aataaagcac tttaagtgct ttattttttt agtgtttttt tcatcaatcc aatgacatat
    47161 tcttttgttt catcatcaac ttctagaaat aactgagcaa attctttgat ttctttatta
    47221 ttaatatcat caagtttatt cagattaggt ttgtcatcaa aatcatctaa tgtgcaatct
    47281 aatactctag caattgattt caaagtctcg agttttggat ctttcgtaac accagtcaat
    47341 attttgtcaa gtgtaccttt tggaacacca gataatttag acaactgctc agatgtaaga
    47401 cctctttctt ttctcaattc attaattttt tcaagcccca taaaaagatt actcctttct
    47461 agataataat aatatataat atttccattg tcaataataa tatttccatt aacggaaaaa
    47521 ataattctaa aaaaaggttg aatatatccg ttgaaggtga tatagtaaaa gagtaatatc
    47581 catcaacgga aaaggaaggt gagagaattg tacagagagc tactaggtga gatggcaaga
    47641 aatgatttga atagaaaaaa attagcatca aaattaggtg tatctccaaa aacactttct
    47701 aacaaactta aaggtaacac agagttcaca tggaaagagg tgaagcaaat tagagatata
    47761 gttgcaccta acaaaacatt agaagagctt tttagacatg aaaaagaaag tgtaaataat
    47821 taggaggaag atgttatgaa agaattatca aatgtaacaa ccaatgaaga acttggagtt
    47881 aaagttaaat taagtatgaa gatggaagta taggaattaa tgtagaagat acagctatag
    47941 ggtttggatg gtgtcagaca cagaataaaa atggtaagca atatgtatca attagatggg
    48001 aaaccatcaa taaatactgt aaagaattta gtttccccaa tttgttgggg aaagatgact
    48061 ggagtaggtt tattaggtgt cattcaaacc gacaccaaaa taaaaagcta gggaggaaga
    48121 aattatgagt aataatctac aaatatttaa aaataatgat tttggagaaa taagaacagt
    48181 tgaaattgat ggtaaactat attttgtagc cacagatatt gctagatgtt taggttataa
    48241 agatacaact aatgcaatta aacaacattg taagtgggtg gtgaaacacc acataccaca
    48301 tccacaaagt aaaactaaga ccttggaagt aaatgtaata ccagcaggtg atatgtatag
    48361 attaattaca aatagcgaat taccaagcgc tgaaaaattt gagcgttggg tatttgatga
    48421 agttctacca tcaataagaa aaacaggtta aagtacatag aaacaaaaaa tatacaatta
    48481 atgtttttct cgaatctaag tactgaatat ctttttgaaa ttgaagatga agttaaagaa
    48541 aaatataggg ggtaacaaac atgaataact tacaagtaat agaaagaaat aacaaaagag
    48601 ttttaactac acagcaacta gcagatgtat atgaaacaga tgtaagaaat ataagcaaca
    48661 attttaacaa taacaaagat agatttattg aaggtaaaca ttatttttta ttacaaggtg
    48721 atgatttaaa gaattttaaa ggtattcata cagaatatga aaacctaaaa tttacttcaa
    48781 aaatgtatct ttggactgaa agaggagcaa atagacactg caaaatattg gatactgaca
    48841 aagcttggga gcagtttgat aacttagaag agtcttactt taacaaaaag aaagatacct
    48901 taattacaaa tcaattaagt ccagaattgc aaatgtttaa acaaatattt gatactgtag
    48961 caaaacaaga aatagagcaa aagcaaataa aacaagagat aacagaaact aaacaagaaa
    49021 tacaaagcat aaaagatgta gttacattga atacaactga ttggagagaa gaaacaagaa
    49081 gattattagt atcaatgtcg caaaacttag gtggaaatga atatataaat actcttagaa
    49141 aagaaagtta tgaatttctt tgtaaaagat ttaatgttga cttgaagcga agattaaata
    49201 atagaagaag aaaaatggca gaagaaggtg tatgcaagtc tagaagggaa aaatttaatt
    49261 atctggatgt tatacaagaa caaaattatt taatagaagg ttatgtaatt gtaataaagg
    49321 atatggcttt aaaatatgga atatcaagtg atttaagcaa aaattgcaat aattaaataa
    49381 gtataagaca agtttatgag ctcatatttt ataacaaggg gtgatgttat gaaaatacta
    49441 caacaattta aaccatacaa atatgatgaa gagaaaaaca tagaatatga tgaaaaaatt
    49501 atagctaatc aaaacacaga agtttatata gtatatccac gtatatctga tgaagagaat
    49561 aggagaagat ggaaagagtt tgatgaagta gccaaagaag tagctattaa tatagcaatg
    49621 aagaaagctg agacagtaga aagttaagaa agtagagaag ttgctaatac ttagcacttt
    49681 ctcaaagaag aaaattggac aactattttt aaacaactag gaataaataa gcgatagtat
    49741 gtttgaaaga aggtgatgaa attgcttagt cttgatatta gtaagaaaaa tgtgatgact
    49801 cttaaaaaag atggtaagtt tttagcagat atagtattta aggacattaa aactggtaaa
    49861 aaaatatcag ttggaacatt aaataaaaaa agtgctggtc aaagtaacca acacaataaa
    49921 taaaaaaatc caaatagagt ataacacaaa aagggggaga tttaaaatag gaaatctaac
    49981 attttaaaag atttaaatat gtcataatga tagcaattta gaatgaatta actttaggtt
    50041 atgctgctaa agaaaggagg tgtaacaatt attaacttta gaagattctt agaactgtaa
    50101 ttatgataaa ttaggaggga tttaaatgga aacagctaga ttgatagcaa taggtcaaat
    50161 taaacaggct gaaaaagaaa taagtagatt acaaggtaca aaaaataata gtagtttaat
    50221 gtggtgggaa gccgtgaaat ttgctagcca aaatatatta gagggtcttg aacatgatat
    50281 tgagttagaa gcatcaactg aatttaggga gtttatgata atacaagaag aacttgaaag
    50341 agatagacca atagatgtcc agctataaga aaagagccta tgccaaggct caattcagta
    50401 aaacaataaa ttatatttat taaattatat atcaaaacaa taatattatg caaataaaaa
    50461 attagattat acatatagta gaaagtttag gtgatattgt gaatgttgta aaagggtgta
    50521 ataaacaatt gcatgtaaca ttaaatagca cttgtttgca agataataat ctaagttggc
    50581 aagctaaggg tcttcattta tatttaatga ctaaggcaga aaatgaaaca atatacttag
    50641 aagatttaaa aaataaaagt agcaatggta gagattcaac agcaaatatt ttaaatgaac
    50701 ttatagaaaa aggttatgta agtagagaga taagaagaga tgccttaaca ggtaaagtac
    50761 ttggggggta tgagtacaaa atatatgaag agtcacttaa aaatattgaa aagtaggtga
    50821 tatattgaac tttgataacg aaacatattt tcatataaat tttgaagacc cttttacaag
    50881 ggttccaaat gcgatattag ataataaaaa tctaacttat tcagctatag gggtagtgac
    50941 acaaatgtta agatttcaaa agtcagggag ccacaaaata tatgcaaaat cattaattag
    51001 ttatagaaaa gatagtaaat caaggataag cagtgcttta aatgagctta taaatgaagg
    51061 atttgtaata agaagtaaaa taagaaatga taagggtcaa ataaaaggat atagatatga
    51121 tatatttgat acccctcaaa ttaaaataga agaaaaagaa gatgttaaaa gtcaaccgtg
    51181 tttcaatata ccgaatacgg ttaatcccga aatcggaaaa ccaggaagcg aaaaaaccgg
    51241 cgacagtaaa actgaaatcc agtttttcgg caacataaaa gaaaatagta taaaagaaaa
    51301 taataatact attattacta ttaataagga gcaagaagaa agcgcatata taaaaaaata
    51361 ttatgaaact tatataggtt taattacacc taataatttt atagagctag caggttattt
    51421 agatgatgga atggaggttg atgtaattat aagagctatt gatgaagcaa catcaaatgg
    51481 agttaaaaat tatagataca taaagactat attaaataac tggatagaat ccggtgtgaa
    51541 gacaaattta gatttaacag agtatcagaa tgaatatgaa aagaaaaaaa gaaaaagtaa
    51601 tagtttggga ggagtaaaaa atgacaaaca aggaaaaaga aattctcaaa caaagagtac
    51661 agaatttgat tttaacagta aagaaacaag aatcaatgac aacgaacttg aaagagcaag
    51721 acaggcactt agagacattg gagttgaacc aagatactga atataaatgt ttaaaatgta
    51781 aggatagact tttcatagaa accgatgaag gttttaaaga atgtaaatgt aggaaactta
    51841 ggatagcaga aaatatttta aaaaatagtg gagtaagtga agaatttagg aaattaaagt
    51901 ttgataattt taattaccaa gtggattctt cagtagcaaa agcatttact aaagctattg
    51961 agtactcaaa ttattttgaa caaataagag agattagaag aaattcaatt atatttatgg
    52021 gacaagtagg aagtggtaaa actcatttat cactagcaat agctaatagt ctaatgaata
    52081 ggtctataag tgttatttat atgccttata gagattctat gacattaata aagcaaaata
    52141 taatggatga agaaacttat agaagagaag ttggaaagta taaatcagct aaggttttat
    52201 taattgatga tttatataaa ggcaatataa caaatagtga cataaatata atgtttgaaa
    52261 taattaatta tagatattta aataaaatgc cattgattgt atcaacagaa aaaaattttg
    52321 atgagcttct cgaaatagat gaagctattg gaagtagatt aattgaaatg agtaaaaatt
    52381 atttgattga attaaagggc aaaagattga attatagaat ttatggggga taaaaatatg
    52441 gataaaaata aaatgctgaa aacgttagtt agaaaggctc aaagtggaga tgaattagct
    52501 tttaatgata tactaaatgt tcttgataaa gagataaaaa ttaatgcatc tatttatgca
    52561 aaatatttag aaggtatttt tgaaaaggat gatttaatag cagaagcaca agcaggatta
    52621 tggaaatcta taatgaatta taaaattgaa atagaatatg tgagtgctta ttttcaaaaa
    52681 gttataaaaa ataacatact tagattagta aataaaagta aaacaaaaaa gtttacaaat
    52741 gagattttag ttttaaataa aaatgtagat tctaatgaat atacagaact tatagagttt
    52801 atacaagatg aaggcttatt ggtagatgaa gttataattg agaaggaaag agcagaagaa
    52861 atagaagctg agaaaaaatt acaaatgaaa atagtgaaaa gaaaaattag atatattcct
    52921 cagccacaaa aggaaattat aagaatgtat ctaaaagaat atgacacaga aaaaatatca
    52981 aaaaaaataa ataaatctta taacgcaata tatagtagta aatatagagc agtacaaaat
    53041 cttaaagaaa tgtgtttacc agaaataagt aagtataata taactatata atacctagta
    53101 taaaaataaa ataggatata caaatattgt atatcctatt aaaaaatgat tattttggag
    53161 gaattaatat gataactgcg tttaaaacaa aagaagaaag agaaaaagaa gtattggaaa
    53221 aagcattaaa ttctttttct ggaattcaaa aggatagagc aagaatttat cttactgaga
    53281 ataaggttaa tgatagatta tttttaagta atttattagt gaaatacaag tttgaaataa
    53341 gagataactt aaaggatatg gaaagaataa gagatgaaat acgagaatat aaatcgtatt
    53401 taaagcaaga gcttggtaat aagactaaga taaaagagta tataaactat ttagaaggtt
    53461 tacttgatag ttgtgaatct cttatatgtg cctatggaaa tgctttaata ccattatttg
    53521 atagtataaa taaagaattt actaaaaaag aaatatgtca attgattgga gctaatgaaa
    53581 agatattaga tgaatactat gaatttatga aaaaacattc taaagaagaa atgagcaaag
    53641 attttaattt tatatatgaa ttaatctttg ttcatcatgg agaatataga tggagaaaag
    53701 gaagatataa agattttgtt gattgtccag attgggaaat gccactattt aatgctttat
    53761 ggagtcatat ggataatttt atagaaaata ataaagaaat acaagaaagt atgcattctg
    53821 tatttgatga agtatttgga gatatatctt actttatgaa tggtgatggt acaatggaaa
    53881 aatcagtaca agaaataaat ataaaagaat taataagtaa ttatagagat tatggaaata
    53941 gcactgtagt atttcagttg aagaaaaaat caattataga tataacaata aattacaagc
    54001 tcaaaagaca aagaggtgat gttttaatct ataaagtctt tgatagtgaa gataatgaac
    54061 ttggagaggt acataagatt atataagctt aatatgaaat ttaaagataa ataaaaggag
    54121 ctgtttaagt ggataaagaa agtataaaag aaattgtaag agaattgaga aaagaagaaa
    54181 gagaagatag aaaaaaagga gtcttatata atactagatt attaatgaaa cattataatg
    54241 attttaaaag acatataaac ttagcattaa gtgaagctaa agaagtaaat tatttagaag
    54301 aagatttgtc tgattttgaa gatgaagagt tgtatatttt aagtattaaa aaaagtaaaa
    54361 caagaactat tattatgata gctcatatag attcagcatt aaaaacatta aagttaagac
    54421 aagagagatt acaatcatat gaaaaatata gagcattaga gctttactat tttgatgaaa
    54481 aaacttatga agaaatagca gaaatattaa actgtggagt agttacatca agacgttggg
    54541 ttaatgagat gataacagag cttggtatat atttatttgg tgtagatggt ctaaaatcaa
    54601 ttgtttgata aatatatgat aaaaagatga tattttaatg atattttaat cctgttataa
    54661 tggtagtatg aaacaagtgt ataatatact ccttaaaaaa gactaagtac ccctaactta
    54721 gtctttttta tatttacaac aaaggagaat aaaaaatgaa catgattaat ttaagagaaa
    54781 agataataaa agaactaaat gaatttaata taaaagcaga taatgttttt ttagaatatg
    54841 cagttaaaca tattgaaaat tttatgaatg aaggtataga tgatgaagag ttattaataa
    54901 gaggtgttgt gcttggagct agttatgtag ttaatataga aaataaagac ttagattaat
    54961 ttctaggtct tttacatttt ataggttaag tttgtggtaa aatgtactaa atgaattagg
    55021 ggtgataact atgaagaaaa atatcttagg agtattgcta ccattattaa caatgattat
    55081 aatatttttt ctatcatttg aaaatacaat aactaataat ttaggattaa gtgagatgga
    55141 tataaaagga atccttattt caggtgtagt attgtatata ccagtttcat ttttagttaa
    55201 tggtataata tgtgctaaaa aacaaataaa ttggaaaatt ccagctttaa tatcactttt
    55261 aggttcagtt gttataatga tgtatctaag atttgatagt actgaaatgg cattgtattt
    55321 atcatattat tctatgtctt attgtattgg atattggata actagtgtaa tgaagaaata
    55381 aaattaaaag attactttta tatattatgg taatatgaaa gaaagtaatt attagggggt
    55441 ataaatatga aatgtcctaa ttgtggtagc gaaaatatag aacaaggtat ttctacagtt
    55501 agtgaatcag gattcgttat atatagaact ggtttagaat acaatacaag attttccact
    55561 aaggtatcta aaacatattc tgacttatgc ttagattgtg gtgaaatagt tagaacttat
    55621 ataaagggtg agactgacag gaattggtgt aaagattaga aataaaaata cataagattt
    55681 agactatctt tatagatggt cttttttatg caataaatta aaaagataat gataaatatg
    55741 ttataggtta aggttttgaa cttgtgaaac agagtaacag aacttaatag gaattagctt
    55801 tattctttat tatatggtat aatgtaaaat agagataagg aagtggttag tataggaata
    55861 ttaaaaagtg ctgaattagt tagaaagata gcacaaagaa ttgctagaga aaaaggaata
    55921 agagagcaag aagcatgaaa tgatgctgtt acagagtaca agcaaaaaca tatatactta
    55981 gtctagagaa tcatctttat agatggtctt tttttataca ataaattaaa gaagagcatt
    56041 atttagaatt attttgtagt tgtcgaacga ttgttgaagg atattgacct ttaaagttga
    56101 agcttatact ttggagggga taatgcagaa taaattaatg agagtgaata atagataggt
    56161 gtatttagga gggataaaaa ttgagcatta aagttaaagt atgggctaaa ttaccatata
    56221 ttataaaact agaagaagag aaagattatg aatttagttt tctatttgat gattttgatt
    56281 tatttaagct taatatgagg tttaatgatg aaaatgattt tttaatttat aataatgaat
    56341 atcctggtaa tgtgtgtcag catatagaat tagaagtaat ttataaatat gttgattata
    56401 caaaatataa aactacaaaa tgtattaata gtaatgacaa ttattttgaa gtagaggtgc
    56461 cattagataa aactacagag atttttggat gcatgaataa aagacttaat gaaatattaa
    56521 attttttaag agagaagtct aatatgtttt ggattgatga atttaatctt acacatataa
    56581 attatcattc tgagaatgag gtacgtttta acttttattc tccgaatgta aatccaagtt
    56641 ctgttgtaac tagttttata gaacatacag attactatat gatttctaaa aacttcaaaa
    56701 caaataatgt tggtgaagat acctttaaaa actttgattc taataagata aaaatgaagg
    56761 tttttaatga atatatagac aaagcagaga aagcactgta tgaatataat tatgaaaatt
    56821 ttataatata ttgtagtata tcagttgaat catttattat tcaatatata gatgaaatag
    56881 ctaatcaaga cgatattatt tataaacaac ttgaaaaaac aaactctaat tatataaatt
    56941 tgtattataa tgtgttatta aaatatctaa caggcaaaag ccttatagaa gttgataaaa
    57001 aagcatgtac acatttaaca agactttata gattaagaaa ttcattaatg cataagggaa
    57061 ttatagatag taaatcatta gaaaaagcag gtataatgaa acttgatttt aatgagtgta
    57121 ataaaatttt agattcagca aagacaagtt ttaaattagt aaagagtata acagttaaac
    57181 ctaagaatga tattaattaa taaaaataat aattactgga aaagaactca ataaataggg
    57241 ttcttttttt attcccaaaa cgacaaaaac gaggtggtgg tgtggcaaaa tatgaatact
    57301 ggataacaga agaaggatta attaagattg aaggatgggc aagagatggg cttacagatg
    57361 aacaaatagc atttaatatt ggaataaatg tcaaaacact atatgactgg aaaaagaagt
    57421 atagtaatat ttgtaatgcc ttaaaaaagg gaaaagaagt aattgacagg caggttgaaa
    57481 atgccctatt aaaaagagca ttaggttatg aatatgatga gataacatat gaagaaggtc
    57541 aagaaactaa aagagtaact aaacaagtag taccagatac tacagcacag atattctggt
    57601 tgaaaaatag aaaaccagcg gaatggaggg ataaaagaga tattgaacat agtggtaatc
    57661 taggagatat tacaataaag gtaggcgatg aggaatatgg caattaattt agaaattaat
    57721 ccagatgtat ttaatccaat atatttgaag catcaactta ataataacaa taggtatcag
    57781 atttactttg gtggttcatc ctcgggtaaa tctttttctt tagctcaaag aacagtatta
    57841 gatgtattta aggggaatag gaattattta attgttagaa atgttcaaag cactctaaag
    57901 aggtcctgtt taaatgagat aacaaaggct attaataatt ttaagttaaa tgagtatttt
    57961 caagtaaata aaaccaatat gataataact tgtaagctaa ataataaaca gatattattt
    58021 tgtggcttag atgatgttga gaaagttaaa tcaataactc caatagatgg tgtaataact
    58081 gatatatggg tagaagaagc aacagagaca gattataaag ccgtcaaaca acttgataag
    58141 agacttagag gaaagtctaa agtagtaaaa agactaacat taagcttcaa tccaatactt
    58201 aaagaccatt ggctatatac agagtatttt gatatatggg aagatgataa acagtatgta
    58261 gaaaaagata atgtaagtat tctaaaaact acatataaag ataataaatt cttggcagaa
    58321 gatgatataa aagctttaga aaatgaaagt gataaatatt attatgaagt ttacactctt
    58381 ggaaattggg gtgtacttgg tgctgtcata tttaagaatt ggagagttga ggatttctca
    58441 gatattgaaa gtacatttga taactttagg catggaattg attggggatt tgctgatgac
    58501 ccatttgcat atgtaaaatc acactatgat aggatgagaa gaaaattata tatatgtgat
    58561 gaaatagaag cagttggatt attaaataga gaagctgcac ctttggttag taaaaaagcg
    58621 aatggagatt tagttatctg tgataatgca agtccaaaag atgtagctga atttagtgac
    58681 ttaagaatca atgcagtttc agcaagaaaa ggagctggtt ctattgaata tggtattaaa
    58741 tttttacaag ggcttgaaat tataatacat ccaagatgcc aaaacttcaa aaatgagata
    58801 aataaatata aatataaaga ggataagaat ggaaatatct tacctattgc agtagataaa
    58861 gataaccatt taatagatgc actgagatat agcttagaaa atgatatgga gtatggagga
    58921 ataagcttct taaagtaagg aggtgttaaa tatttatata agtgaaacag atttaataaa
    58981 agctcagcta aaaaaagaga gtacttttaa tctggcgaaa gttatagagc attatatttt
    59041 aaagcataga ccagaaaagt atcaagaagg agaagcatac tattatggta atgctaatat
    59101 aaaaaataaa agaagatatt atattttaga tggtgctaag gttgatgatt ttactaaagt
    59161 taataataaa gcagttaata attatcataa gcttttagtt gaccaaaagg taggctacag
    59221 tgttggaaaa ccaatagtat ttaatgcaga tgataataat tttactaagc ttttaaatga
    59281 attattagga gaagaatttg atgatacaat aacagaactc tatctcaatg caagcaataa
    59341 gggaatagaa tggttacatc catatattaa tagaaaagga gagtttaaat atgtaataat
    59401 accagcagaa gaagctattc ctatttggga taacaagagg caaaatgaag tagttgcctt
    59461 tattagattt tactttattg aggatataga tggaaataag ataaaaagag ttgaatacta
    59521 tacagaaaat gaagtaattt actttattga aaaaggaaat agttttgttc aagaactttt
    59581 atatgatgaa tatggaaaat taacagagat acaagagggt cattttagag taaataacaa
    59641 agagcaagga tggggtaaag ttccatttat accatttaaa aacaatgaga aaagcgtatc
    59701 tgatttaact ttttacaagt ctttaattga tatatatgat aataacattt ctactcttgc
    59761 agataaccta gatgaagtac aagaagctat gtacatacta aaagagtatg gaggtactga
    59821 tttagtagaa tttgcaaata acataagata ttataaagcc attaaagtag gagctaatgg
    59881 aggggtagat aagctggaga taaatatacc agttgaagct aaaaaggagc ttcttaatag
    59941 attggaaaag aatataatta tctttggtca aggagttaat ccagaatctc aaaacacagg
    60001 tgacaaatcg ggtgtagcac ttaaattttt atattcacta cttgacttaa aatgttctaa
    60061 gactgaaaag aagtttaaaa aagcaattag agagctttta tggtttgtgt gtgagtattt
    60121 aaagataagt ggtagtaaga gctatgatta taaaacagtt caaattactt ttaatcactc
    60181 tatgataata aatgaagctg aaaagataga tatggcagct aaatcaactg gaattgtatc
    60241 agatgaaact attgtttcca atcatccttg ggttgaggat gttaatgacg aacttgagag
    60301 acttaaaaaa caggaagata ctcaaaaaga gtatgatgat ttaattccta ataatcaaga
    60361 tggtgttata gatgaaatat aaagattatt ggagaaagag atttgaacaa ttagaagaag
    60421 ttcaaaataa caaaagtgta aaatattatc ttgaattaga aaagcaatat aaactagcta
    60481 tgaatagtat agaaaaagat atattatcat ggtacaacag atttactgaa agtgaaggca
    60541 tatctttatt ggaagctaag aaactactaa atacaagaga actagaagag tttaaatgga
    60601 gcgttgaaga atatattaaa tatggtaaag aaaatgctat aaatcaaaag tggatgaaag
    60661 agttagaaaa tgctagtgca agagttcata taacaagact tgaagcttta aagttacaaa
    60721 tacagcaaca agtagaagtt ttatatggaa atgaacttga tggtattgat aaactaatga
    60781 gagatattta tacaagtgga tattatcata cagcttttaa tgttcaacaa ggagtaaacg
    60841 ttggttggag tttaatgagt cttgatacta atagaataaa taaaattatc tctaaaccat
    60901 gggcaacaga tggattaaac tttagtgaaa gaatttgggg taagcataga cttgctttag
    60961 taaatgcatt acatactaag ctaactcaat caattattag aggtgaaaat ccaaagaacc
    61021 tagtaaatga cttttctaag aggtttaatg tatctaaatc acaagctaag aatttaataa
    61081 tgactgaatc agctttcttt gcatcagcaa gtagaaaaga ttgttttagt gatttagatg
    61141 tagagaaata tgagattatt gctacattag atttaagaac ttcaaatata tgcagagagt
    61201 tagatggaaa agtatttgat atgaaagatt atcaagttgg aataacagct ccaccatttc
    61261 attgtcgttg taggacaaca acagctcctt tttttagtga tgaagaaggc tatagagcag
    61321 caagaggaga agatggaaaa acatattatg taccatctag tatgaagtat aatgagtggt
    61381 atgagaagta tgttaaacat aatagtatct tagaaataaa aaatagtgct ataatagata
    61441 gcataaaaga agatattaaa aatggtaaat ataatttaaa tattcatgat gggaaacaag
    61501 gaaaacattt aaaagagcat aataattata tagaaggaag aagctattta actataacaa
    61561 aagaagaagc tcaagaactt gtgaataagc atgctggcaa tggaatcata aaatttaatc
    61621 gaagtggaga atgggataaa aaagaactta tagaagttga taagaatata ggggtcaatg
    61681 ttaataatat tacgggtgaa aaaactctta caaataagtt taagatacat tattccaaaa
    61741 ctggaacaca tatagtacca gctttataag gaggaaaaat aaaatgaaat tatgggaata
    61801 tgtagggaaa aatgttcaaa taacttgtgt agataagcaa ataataagag gaaagtgtga
    61861 tggatataca caagctttag ataatgaacc agaaatagca agtatatcaa tagctaggga
    61921 tggttatgga attgaagttt atgaaaatga aatagaatct atcgaaaata taaataagga
    61981 atgactaagc atgtacttaa aaataagtag atgcttttat tttgtaaaaa atgaaaggag
    62041 aaatttaaaa tggattggtt aaaagaattg ctagaaggaa taaaagtaga ggataacaaa
    62101 attgatgtag cttctcttca aaaatctata gaaaagaaaa taaaggagac tacagttact
    62161 caagaagatt atgcaaatat tgaaacacaa cttaatacag ctaatgaagc tattaaaaag
    62221 tttgaaggag gtatgacaaa agaagatgta gagaatctaa aaacaactta tgaaactgat
    62281 aagaaaactt tggaagaaac ctacaaaaaa gaaattgaag aaaaagattt taattactgg
    62341 ttaggtgatg cttttaaatc tgttaaatgt agagatgaaa tagcattaaa agctcattta
    62401 gatatagaag cactaagaaa tagtaaagat agacaaaaag cttttgaaga gcaaataaac
    62461 cctttgaaac aggataaaga ttatttgttt aatgcaacac tagaaggtga agagcctaaa
    62521 atagatacta taacaccagg gcaagagcct aagataaatg attttggttt taattttact
    62581 ggggtaagac ctcatgaaaa taataataaa taggaggaaa taaaatggca gcactaaatt
    62641 atgcaaaaga atattcaaat gttttagcac aagcatatcc ttatacttta aacttcgggg
    62701 atttgtatgc aacaccaaat aatggaagat atagatggac tggttctaaa acaatagaaa
    62761 taccaactat atctacaact ggaagagtag attcaaacag agatacaata gcagtagctc
    62821 aaagaaacta tgataatgct tgggaaccta aggtattaac taatcaaagg aaatggtcaa
    62881 cattggttca tccagcagat ataaaccaaa ctaattatgt ggcttcaata ggcaatataa
    62941 caaaagtata taatgaggaa caaaagtttc cagagatgga tgcttactgt atatctaaaa
    63001 tatatgctga ttggaccgca ttaggtaata cagcagatac aactgttctt acaacaacaa
    63061 acgtattaga agtatttgat aagttaatgg aaaaaatgac agaagctaga gtacctgaaa
    63121 atggaagaat attgtatgtt actccagtag taaatacact tatcaaaaat gcaaaagaga
    63181 tacaaagaac agtaaatata aaggatgcag gaacttctct taatcgtcaa acaactgata
    63241 ttgacacagt taaaataatt aaagtaccat ctaatctaat gaaaactgca tatgatttta
    63301 caactggatg gaaagtagga gcaggagcta aacaaatctt tatgtcctta gttcacccaa
    63361 gtgcaataat tacacctgtt tcttatcagt tctctaagtt agacgaacca acagcagtta
    63421 cagagggaaa atacttctac tttgaagaaa gttttgagga tgtatttata ttaaataaaa
    63481 aagctgatgc aatacaattt gttgttgaag gagctggagc ataatggcac aagtaaggaa
    63541 attaaataga atattaacta tagaagaatg taaaatagat gatttcttag agatgggata
    63601 tgatttgata gatgaaactg gtaaggcagt aaagtatggc aagtcattaa atgtaaaaga
    63661 tttaatagct gaaaataata ttttaaggtc aaaagttgag tctttagaag aagaaaataa
    63721 gcagcttaaa gagaaaaata aacttactaa aaagtaggtg aaaattatgg aaaataatat
    63781 aattgatgaa atagaaaaaa gacttgaaag ttttggatat atattaaaag atggagataa
    63841 gtggttaata ggttttgtaa gagaaaaaat agaaaatatt attaaactag attgtaatat
    63901 aaaaactatg ccaattgaat tgaaagaaat tgaagttgat atgatagttg gagagttctt
    63961 atttaccaag aaaaatatgg gtcaattaga tatagaaagc attaactttg aagctgtaga
    64021 aaagtctata tcagaaggtg atacaaaggt agattttgct ataggaagtg gttctcaaac
    64081 accagaacaa cgctttgata gcttaatagc ttatcttact acttatggta agaataagat
    64141 attaaccttt aggtgcttaa gatggtaagt aaaactagaa aagcaataga aatgttatat
    64201 agagataaat gtactatagt tgagtatcag ccaattaaag accctgtaac aaaacgaact
    64261 aacaataaag aagtgattgt attagaaaat caaccatgta aactttcata taaaaatata
    64321 gtttctgcta cagaagggaa attagctaag ctagagcaaa ctattaaact ctttatatct
    64381 ccagatatag aaattaaagc aggttcaaaa cttattataa atgataaaga gtatgtaaga
    64441 agtggagaat cagctatata tccaaatcat caagaaataa tacttgagct atttaaggat
    64501 aaagcataat ggctagatgg ggcagtgttg attttagaga gtttaaaaga gtttgtaaaa
    64561 agatggagaa gcttacaaag attgatttag ataagttttg caaggatgca gcaagagaat
    64621 tagcagcacg attacttggg aaagtaatta gaagaacacc agttgataca ggattcttaa
    64681 gacaaggatg gaatggagtg gcttacgcta ggtcgcttcc tgtgtataaa caaggaaata
    64741 attatattat agaggttgtt aatccgactg aatatgcctt aacacaatgg ggcatataaa
    64801 acccagcaaa atcggtaaac gctaagtata atagtgttac attataaagt aggtagaata
    64861 tggacataga ataactcttg atttataatg tataaaagag gtgattttat ggcaaaattt
    64921 ttagatatta caggaaaaaa atttggaagg ctaagagtca ttaaattttc taaagagata
    64981 aaaagtggta aaagaaatag aaaatattgg ttatgtaagt gtgattgtgg aaatttcaaa
    65041 gaaataagaa ctgactcttt aactagtggc ttagtacaat cttgtggatg tttaaaaaaa
    65101 gaacaagata aattaaattt aacagacaaa taccaattta aaaagaaata taaggttcaa
    65161 aataaaagac tttacagtat atggaagggt ataatatcta gatgtacaga taaaaataat
    65221 aaaagataca atagatatgg tgaaaggaat ataattgtgt gtgatgaatg gttttgctat
    65281 gataattttg caaattgggc attgagtaat ggatattcag agaaacttac aattgataga
    65341 ataaataatg aaggaaatta tgaatcaagc aattgtagat gggtggatat aaagacacaa
    65401 tgtagaaata ggtcaacaaa tatattagta aagcatgaag aaaaagaaat tacattgata
    65461 gagctttctg aaaaaacagg tatttcatat tcttgcttaa gaagtagata ttctaaggga
    65521 ttagtaggaa ataagcttat agaaaaagtt aagattattg aagaaagcag agctaagtta
    65581 tctattgagg atgtaaaaga aattagaaaa aagtattctg atggatatac aataaaacaa
    65641 ctaagtgaaa tatatcctgt aacatattca tctatatcaa atatagtcca tagaagaaca
    65701 tggaaaaata tttaattaat tatatatgcc aataccgagg aaaacctata gattgcgaat
    65761 aggctatagg tttccgtaga gcgtagagag tgaataaata taatctctcc aagagtgctg
    65821 ggcaactaaa taaagtttat tttgttgatg atgtacgccg aacttatagg aaactataag
    65881 agctagagga taaaaagcct ttaggataac aaaatgcata tgttgagttt gggcatagaa
    65941 ctaaaagtgg taagggatgg gttaaaggac aacatttctt aacaatttca gagatggaac
    66001 tacaaagcca aattgataag attatagaga aaaagttatt aatattactt aaaggagtat
    66061 ttgatgctta ataatataat tgatggaata tctattaaat tagataaaac atttggagag
    66121 agttatacaa tttatagtga agatgtggag caaggtataa atgaaccttg tttttttatt
    66181 tgccctctaa atccaagtaa gacatcttat ccaaatggta gaacactaaa aaagaactct
    66241 tttgatgtac attattttcc tcgttcaaaa gataagagtt ttgaaataaa tgaggtagct
    66301 gagatgctac ttgaggaatt agagtatata gaaattgatg gagatttagt tagaggcaca
    66361 aatatgaatt ttgaaattat agataatgtt cttcatttct tcgttgatta taactacttc
    66421 actataaaaa gtaatgatac agaaaaaatg aatgatgttg aattatttgg tggtttgaag
    66481 agaggtgata attttgaata aaacattaag caaagaagat gactacaagt ttactaagga
    66541 gcaaatagtt aattctaaga agtatgtaaa tagaaaagac ttattaaatg caattttaaa
    66601 agaaaatgag ttatattcct tctcagaagt agaggaaata ataaataatt ttatgaaagg
    66661 agtgagttag atggctttag gtggaggaac atttgtaaca caaaataagg tcctacctgg
    66721 tgcatatata aattttgtaa gtgctacaag ggcaaccagt tcattatcgg atagaggtat
    66781 tgttgcaatg cctttagagt tagattgggg catagatgaa gaaattttca cagtaaccag
    66841 tgatgatttt gagaagtatt caactaagta ttttggatat gattatactc atgagaagct
    66901 gaaaggtttg agagatttat tcaaaaatat aaggttggga tatttttata aattgaataa
    66961 aggtgttaaa gctagttgca gtattgctac agctaagtac tcaggtacta gaggtaatga
    67021 tttaaaagtt atagttacaa caaacattga tgataacact aagtttgatg ttgtaacact
    67081 tttggataat aagaaagtag atacccaaat agcaaaagtt attacagact tacaggacaa
    67141 tgactatatt acttggaaga aggatacaac actagaagca agtgcagggc ttgtatttac
    67201 tggtggaact aatggcgaat cagtcacagg agcagagtat caagctttct tggataaaat
    67261 agaaagctac tcatttaatg cactaggcag tttggctaca acagcagaaa ttaaaagttt
    67321 atttgtagag tttactaaaa gaatgagaga taaagtagga gctaagtttc aaactgtact
    67381 atataaaaag aatgatgcag attacgaagg tgtagtatct gtagaaaata aagttaaaga
    67441 tactgggtta ttagaatcta gtttagttta ttggactact ggagctatag caggatgcga
    67501 tataaataaa tctaatacta ataaaaagta tgatggtgag tttgatgttg atgtaaatta
    67561 cacacaaata caacttgaag aagcactaaa gagtggtaaa tttatatttc ataaagttgg
    67621 tgatgaagtt catgtgttag aggacataaa tacttttgta tcatttacag atgataaaaa
    67681 tgacgatttt tcaagtaacc aaagtgttag agtacttgac caaattgcta atgatattgc
    67741 aactttattt aatgaaaagt atttaggtaa agttccgaat gataaggcag gaagaataag
    67801 tttctggaat gatgttgtta aacaccataa agaattagag aatataaggg caatagaaga
    67861 ttttaaaact gatgatgtta gtgtagagct tggaaatgat aagaaaactg tcatagtatc
    67921 tgatgctgtt aaggttataa atgctatgag taagctttat atgactgttt cagttagtta
    67981 agagaggagt gtgatatatg tttcagcaaa taaaagcaag agatacaata agtgcatcta
    68041 aggcagaatg ctatgttact atcgagggta aaagatataa ttttatgcaa gctattaact
    68101 tagaagctaa gatggaaaaa aataaaagtg aagttcctat cttaggtagc actacaaaag
    68161 ggaataaaag tactggaagc aaatacacag gaagtgcaac atttcactac aatacttcta
    68221 tatttagaga gcttctttat aggtacaaag agactggtga agatatttat tttgatatac
    68281 aggtaacaaa tgaagaccca acgagttcag ctggacgtca aactataata cttaaggatt
    68341 gcaacatgga cagtggaatt atagttaaat ttgatgcaga tggtgagtat cttgatgaag
    68401 atatggactt tacatgcgag gattgggaat tggttgaaaa gttcaatata ataaatggaa
    68461 tggaataaaa cacacattta taaattatag atgtgttttt ttatataaaa aattaaaata
    68521 aaaggagatt aggataatat gagtaattta agtgcttttt taagtcaaaa tgcaataaag
    68581 gttgataatg taaaatatat agcaagtgat agatttttag acgaagaagg aaagccagtt
    68641 gaatgggaat taaaagtttt atcttctgag gaagatgaag tattaagaag aaattgtacc
    68701 aaaagagtaa aagtgattgg caataacggg aagccaacag gtcaattcac aagtgaaatt
    68761 gattataaca gttatgtagc tgaattatgt gtagcatcta cagtatttcc agatttaaag
    68821 gatgccgaac tccaaaatag ttatggagtg atgggagaag ctcagttatt aaagacaatg
    68881 cttacagcag gtgagtatgt caactataca gtaaaagtta atgaggttaa tggatttgat
    68941 acaacatttg aagataaagt agaagaagca aaaaactaat taggggcggc gattttgatg
    69001 ctagtatcac gcattattgt atccaaaaat taaagtggaa accaggtgat tatatgggat
    69061 tagagattaa tgagagagca ttagcagccg cctcaatact tattaagata gaggatgaag
    69121 aggaagcaat gaaagaagct gaaagagaga gaaagagggg tagaagaaga tagcaaaata
    69181 aaaaaataaa tatagaatag gtaaaatatg taa
//
LOCUS       DAEOTL010000012        60244 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEOTL010000012 DAEOTL010000000
VERSION     DAEOTL010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60244
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.012"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            107..781
                     /locus_tag="KRH82_001075"
     CDS             107..781
                     /locus_tag="KRH82_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654366.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            769..1929
                     /locus_tag="KRH82_001076"
     CDS             769..1929
                     /locus_tag="KRH82_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8654367.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            2146..2673
                     /locus_tag="KRH82_001077"
     CDS             2146..2673
                     /locus_tag="KRH82_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBG8654368.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            2959..3627
                     /locus_tag="KRH82_001078"
     CDS             2959..3627
                     /locus_tag="KRH82_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654369.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            3630..6098
                     /locus_tag="KRH82_001079"
     CDS             3630..6098
                     /locus_tag="KRH82_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654370.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKITKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIGLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(6338..7762)
                     /locus_tag="KRH82_001080"
     CDS             complement(6338..7762)
                     /locus_tag="KRH82_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654371.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNNINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(7781..8473)
                     /locus_tag="KRH82_001081"
     CDS             complement(7781..8473)
                     /locus_tag="KRH82_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654372.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(8525..9304)
                     /locus_tag="KRH82_001082"
     CDS             complement(8525..9304)
                     /locus_tag="KRH82_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBG8654373.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(9301..10071)
                     /locus_tag="KRH82_001083"
     CDS             complement(9301..10071)
                     /locus_tag="KRH82_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBG8654374.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(10068..10772)
                     /locus_tag="KRH82_001084"
     CDS             complement(10068..10772)
                     /locus_tag="KRH82_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBG8654375.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(11027..11539)
                     /locus_tag="KRH82_001085"
     CDS             complement(11027..11539)
                     /locus_tag="KRH82_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654376.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGYVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            11865..12122
                     /locus_tag="KRH82_001086"
     CDS             11865..12122
                     /locus_tag="KRH82_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654377.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            12265..12891
                     /locus_tag="KRH82_001087"
     CDS             12265..12891
                     /locus_tag="KRH82_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBG8654378.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(13137..13916)
                     /locus_tag="KRH82_001088"
     CDS             complement(13137..13916)
                     /locus_tag="KRH82_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBG8654379.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVVEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(13984..14445)
                     /locus_tag="KRH82_001089"
     CDS             complement(13984..14445)
                     /locus_tag="KRH82_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8654380.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(14421..15098)
                     /locus_tag="KRH82_001090"
     CDS             complement(14421..15098)
                     /locus_tag="KRH82_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8654381.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSKV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            15331..15717
                     /locus_tag="KRH82_001091"
     CDS             15331..15717
                     /locus_tag="KRH82_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8654382.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYTPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVAKESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            15720..17519
                     /locus_tag="KRH82_001092"
     CDS             15720..17519
                     /locus_tag="KRH82_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBG8654383.1"
                     /translation="MYAPFFIRFLLSTLTLSILIAVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDEEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNSSSASKITLSILNDKKIYNP"
     gene            complement(17872..19959)
                     /locus_tag="KRH82_001093"
     CDS             complement(17872..19959)
                     /locus_tag="KRH82_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBG8654384.1"
                     /translation="MIKVVYMRKNKKTRKMIIFGFLMCLLIVIIVFLAKFILDGLNKN
                     KPDEVFKQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHDISIKI
                     NDIKKNKNNDKVINYDSKMDTLAGEISFSNEVLLTRDRQKNYKIKWQSNVIFPELEED
                     NTVRVSKLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVE
                     QIEKKLNASWVKENSMVPIKTIEKIKENTDGTVKEEDKELQESLLSIPGVKISNTEVR
                     VYPFGEKTGHLTGYVQNVNADILKEKEGKRYNDNSIIGKIGLENLLEDRIRGIDGYEI
                     IIADRYGDKKETLVTEPKVDGEDVKLTIDSKLQSKLYDQMKNDKGCAVVMNPKTGEVL
                     SLVSSPSYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITT
                     GKINPNENFGHSSLSWQKDSSWGSYKVTTLKDYGNTANMKNALIYSDNIYFAKAALKI
                     GEDVLAKELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHT
                     ASIYSAFVNDGDMIKPHLEFKKAEFWKKGVFSKEAVKIIRDDLLQVVESPDGTGHSAM
                     IKGISIAGKTGTAEIKASKDDVTGTELGWFNAFTVDENSDKQYIVIAMIEDVKSRGGS
                     HYVIPIVKSVFED"
     gene            20320..20898
                     /locus_tag="KRH82_001094"
     CDS             20320..20898
                     /locus_tag="KRH82_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBG8654385.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKYYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFVEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQINIIKDMVILYE"
     gene            20891..21550
                     /locus_tag="KRH82_001095"
     CDS             20891..21550
                     /locus_tag="KRH82_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBG8654386.1"
                     /translation="MNKQKFHKINLQNWERYTHFYYFSKMTNVGFNLTIEIDITNLLK
                     ETKKRNIKFYPAYLYTITTCLNRYRELKIAYDEDELGYWNTLTPLYAIFHDDNKTFSS
                     IWTEYDENFSIFYENYLADVKEYGKNHGFLAKPNPPRNCYTVSCLPWISFKSFTVHNH
                     GLENYFFPTIEAGKYYQKDEKILLPLSITVHHATTDGYHVSCFIDYIQKMCFNTKIWL
                     H"
     gene            complement(21761..23635)
                     /locus_tag="KRH82_001096"
     CDS             complement(21761..23635)
                     /locus_tag="KRH82_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8654387.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMIKDRETINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(23640..25304)
                     /locus_tag="KRH82_001097"
     CDS             complement(23640..25304)
                     /locus_tag="KRH82_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBG8654388.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            complement(25318..26139)
                     /locus_tag="KRH82_001098"
     CDS             complement(25318..26139)
                     /locus_tag="KRH82_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8654389.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(26238..27002)
                     /locus_tag="KRH82_001099"
     CDS             complement(26238..27002)
                     /locus_tag="KRH82_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8654390.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(26999..27748)
                     /locus_tag="KRH82_001100"
     CDS             complement(26999..27748)
                     /locus_tag="KRH82_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8654391.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(28252..28857)
                     /locus_tag="KRH82_001101"
     CDS             complement(28252..28857)
                     /locus_tag="KRH82_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8654392.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            29036..29674
                     /locus_tag="KRH82_001102"
     CDS             29036..29674
                     /locus_tag="KRH82_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654393.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVIGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            29812..30474
                     /locus_tag="KRH82_001103"
     CDS             29812..30474
                     /locus_tag="KRH82_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654394.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            30474..31655
                     /locus_tag="KRH82_001104"
     CDS             30474..31655
                     /locus_tag="KRH82_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654395.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTLWSKNFFYFLVISFGI
                     ISTMATVVYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGAKFIIKFY
                     T"
     gene            complement(31836..34496)
                     /locus_tag="KRH82_001105"
     CDS             complement(31836..34496)
                     /locus_tag="KRH82_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654396.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKISASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(34493..35176)
                     /locus_tag="KRH82_001106"
     CDS             complement(34493..35176)
                     /locus_tag="KRH82_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654397.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTYGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(35520..36473)
                     /gene="blaCDD"
                     /locus_tag="KRH82_001107"
     CDS             complement(35520..36473)
                     /gene="blaCDD"
                     /locus_tag="KRH82_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBG8654398.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKCVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(37015..39129)
                     /locus_tag="KRH82_001108"
     CDS             complement(37015..39129)
                     /locus_tag="KRH82_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8654399.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMVEKKTLEWSDVYPFIYIHATYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(39387..40247)
                     /locus_tag="KRH82_001109"
     CDS             complement(39387..40247)
                     /locus_tag="KRH82_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654400.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(40858..41482)
                     /locus_tag="KRH82_001110"
                     /pseudo
     CDS             complement(40858..41482)
                     /locus_tag="KRH82_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860815.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
     gene            complement(41502..42116)
                     /locus_tag="KRH82_001111"
     CDS             complement(41502..42116)
                     /locus_tag="KRH82_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBG8654401.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDIERYERIREISAEMIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAVIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGTFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFEACRTDTWTVIFD"
     gene            complement(42184..42546)
                     /locus_tag="KRH82_001112"
     CDS             complement(42184..42546)
                     /locus_tag="KRH82_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8654402.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(42844..43308)
                     /locus_tag="KRH82_001113"
     CDS             complement(42844..43308)
                     /locus_tag="KRH82_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBG8654403.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(43572..44993)
                     /gene="nhaC"
                     /locus_tag="KRH82_001114"
     CDS             complement(43572..44993)
                     /gene="nhaC"
                     /locus_tag="KRH82_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBG8654404.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(45023..46087)
                     /locus_tag="KRH82_001115"
     CDS             complement(45023..46087)
                     /locus_tag="KRH82_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBG8654405.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFNNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(46072..47481)
                     /locus_tag="KRH82_001116"
     CDS             complement(46072..47481)
                     /locus_tag="KRH82_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBG8654406.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(47481..49685)
                     /locus_tag="KRH82_001117"
     CDS             complement(47481..49685)
                     /locus_tag="KRH82_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBG8654407.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(49679..50053)
                     /locus_tag="KRH82_001118"
     CDS             complement(49679..50053)
                     /locus_tag="KRH82_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBG8654408.1"
                     /translation="MKKREDDFEVRRKHLQELSEDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(50131..51561)
                     /locus_tag="KRH82_001119"
     CDS             complement(50131..51561)
                     /locus_tag="KRH82_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBG8654409.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKAIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(51554..51862)
                     /locus_tag="KRH82_001120"
     CDS             complement(51554..51862)
                     /locus_tag="KRH82_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBG8654410.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKVNPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(52006..53073)
                     /locus_tag="KRH82_001121"
     CDS             complement(52006..53073)
                     /locus_tag="KRH82_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBG8654411.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMVEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(53329..54702)
                     /locus_tag="KRH82_001122"
     CDS             complement(53329..54702)
                     /locus_tag="KRH82_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654412.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRKNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(55245..57203)
                     /locus_tag="KRH82_001123"
     CDS             complement(55245..57203)
                     /locus_tag="KRH82_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HBG8654413.1"
                     /translation="MKRAYYSSSVNEFIVKDIFTIFGEITCNDQFAADDLQKNTWKKE
                     IGILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPRHAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQKDQRIRMMKENILETYCCNEFNIGKYI
                     KKICTTYNRSSFNSDTWINSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKTHNRKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGIRKSEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKRKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFESLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSENVSTFVKAVLDVDKVAAKELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQNKIDATNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNNHFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFIIFVPI
                     GDESDITMQPNFYNGVYEYLKEIGIEEL"
     gene            complement(57396..58586)
                     /locus_tag="KRH82_001124"
     CDS             complement(57396..58586)
                     /locus_tag="KRH82_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HBG8654414.1"
                     /translation="MDKNKYKIETLMNHVGENLDGDYGAVNPPIYQSSIFARSTYEDI
                     EAYFEGSKDGYLYSRTKNPTNDILEAKLSALANAEASITFGSGMGAISSAILHFVKNG
                     DHIIASNNLYNPTMNFITKELKEKGNIENTIVEGDRIEDFENAIKQNTTLIYLECPST
                     SVFKMQDIKAIVALAKTHNIKTVIDNTWATPLYQRCIEMGIDLEVHSLSKYLNGHSDV
                     VGGCIIGSKKDIEEIRGSELALYGAKLAPFEAFLVIRGLRTLHARLSVHTKNAKEVVE
                     FLDNHSAVTKVYHPLSKYFNQKELAKKQLLNYTALLSFEIDAKDVNDVKKFVNKLDLF
                     KIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLINDLNDA
                     LSIL"
     gene            complement(58686..60152)
                     /locus_tag="KRH82_001125"
     CDS             complement(58686..60152)
                     /locus_tag="KRH82_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBG8654415.1"
                     /translation="MKRKVTIQKQAISIVLFMAVLFCGLLLPMINNKPEYSLPIESIM
                     FISASIISLFIVVTTNKTWEEVFESGLDGVKGALPGLIILLVIGPLIAGFIMSGLMPM
                     LVYYGVKLINPRFVYATALILSALFSSFTGTSWGSAATIGVVMMGVGNAIGANNAIIA
                     GAIVGGAYFGDKMSPLSDTTNIAAIASKVNLYDHVASMLWTTGPATIIALVIYIACGF
                     IFPATNTNLNSPEITRLLADLSGMFNFNIILFIPLLIVLVGSAMKKPAIPVMTIAAFL
                     SLAFAVIFQGFSLADVLIGLNSGFSLDMVTWHEYAKPIEGQAYILGFFQKGGFWELGK
                     LLPISTSILFVVGVLGSIDAMPATVNVIFGWVKSRTAIICSSLLTGIAMIAMTANGIA
                     CSFVTAGIFGDKYDENNIDRRVLSRTTEDTGTLLEVLFPWTPAAIFFTQTLGVNVGEY
                     ALWSIVNWGTPIIAVILAVTGIGTYKNSKDKKQSNKVS"
BASE COUNT        20236 a        10312 c         7250 g        22446 t
ORIGIN      
        1 tttaatgatt aagttttgaa atataactaa aaatttgata atttattgag atttttatac
       61 taaaatatac atactataca aacttaattt agaagggagc attcttatga acaataaaat
      121 actcgtcgta gatgatgagg aaggtataat aacactctta aaagattact ttgaaatgaa
      181 tggttatgag gtttacactg ctcaaagtgg aaaagacgca ttaaaaaaaa tatccaaaaa
      241 tccagatatc attctacttg atataaacat gcctgaaata gatggaattg aagtttgtaa
      301 tagaattaga gattatgtat catgccctat tctatttctt acagctagaa ttgaaaacac
      361 tgacaagata aatggttttc gtgctggtgc tgatgattat attgtaaaac cttttgattt
      421 agacgaactt ggagctagag tatctgccca tttaagacgt gaacaaagga agtcaaatca
      481 aactaaaatt aaattttata atgatttaac aatagattac gaaaaaaggt taatttgtat
      541 atataataat cagatttcac tttcaaaaaa ggaatttgat atagtagagc ttctctctat
      601 gaatcctgga caagtatttg ataaagaaaa aatatatgat agagtctggg gatacaatag
      661 caatggaaat agtgatgtta taatggaaca cattagaaaa atacgaatca aactatcaaa
      721 acatactctt gaaaattata tagaaacagt ctggggagtt ggttataaat ggataaaata
      781 aataatatgt cattaaaaaa agctttcttt gttcttactt tatcttcact aattatagca
      841 tcagtactta ctactttcgc atacatttta cttaataatc tatataattc tatacaagat
      901 aagtatttaa aaacacctat aaatacaggt attataacca tagttcaaaa caatgtgaac
      961 caatttagtg attatgataa aacattactt aatataatca acatactcca gcttgtactt
     1021 ccacttatat tttttatagg acttttatta ttagctgata taatttttta caaggtaaaa
     1081 ttaaaaacac ccatagaaat actcaataaa ggtgcaatgg aaatatccaa caacaattta
     1141 gacttttgct tagaatataa taataatgat gaattaggta atctatgtaa tgcttttgaa
     1201 aaaatgaggt ctgaactaaa taaaaacaac ataaagatgt ggactatgat taatgataga
     1261 aaacaactta atgctgcttt ttctcatgat ttaagaaatc ccctaacagt tctaaaaggt
     1321 tactcaaact atttaacaaa atacatacca acaggtaagc ttagtgatga gaagatttta
     1381 tcaaccacac aacttatgtc tgagcatatt aacagaattg aatactatgt agaaaatatg
     1441 agtaatgctc aacgattaga agatttagtt gtttcaaaat ctatgtcgaa tataaacaag
     1501 tttatagaaa acttagatga aaatatatct atcattgcta aacaagaagg aaaatctttt
     1561 acacttaaaa atcaaataaa taatataaat ctattttttg atgaaaatat cattcttaga
     1621 gtcgtcgaaa atataatatc gaatgctttt agatatgcta gaaataatgt atccatactt
     1681 atatatcttg aacaagaact ccttaccttt gtaattgaag atgatggtat aggatttagt
     1741 aaggaatctc taaaattagc tttaagacct ttctatagag ataagacttt aaatgacagc
     1801 aatgcacact ttggtatggg tctttatatc tcaaaaatat tatgtgaaaa acatggtggc
     1861 tctatttcta ttgaaaataa ttctactaac agtgctaaaa ttactgctaa attctcaaca
     1921 agaaattaaa atgattttgt aagctttcac tgctattata taaaatttgt tagtttagaa
     1981 tttataaaat gtatttcaat ttacaaccaa tatatatact attttgtaga agttgtaaga
     2041 gttgcttcaa ttataatatt ttggcaaaag gcatttgaaa caataataga aatatatatt
     2101 taaatatgta gaatagtatg aaattagaat tttggaggtg attatattaa aagttttgct
     2161 aataatatta cattctctcg tattgtgttt gcattgctaa tgcttagttc tacattctgt
     2221 tcactgcctt tctggatatg ttatttttgg tgtggaatta gtgatatact tgatggtctt
     2281 attgcccgaa agttgagaca acaaagtgga ataggtgcaa agttagatag tattgctgat
     2341 ttcatttttg cggttacaat tttggttact gtcggaaaaa atattgctct tcccatgtat
     2401 ctatggtggt gtattgttgc aatagcattg ttacggttga ttagttacag tattggtttt
     2461 tttaagtatc gcacattttc atcgcttcat actttgatga ataaaatcac tggaatttct
     2521 atctttgcgt ttccattact ctatatttgc tttggtcttg atgttgcagg aattatgata
     2581 tgtatcgtgg cttttctttc ttcttttgaa gaaatagcaa ttatgataaa atcaaaagaa
     2641 ttaaatcgtg atataaaaag tatatttatg tgacaactta gaatttgtga caaaaataat
     2701 ttatataata atgaggaagt aaaacataaa aaattatcca caagtttatg tgtaaaatag
     2761 ttttaaagca atagagttgt attgtaaagc ctttagtgca taaattacat tttaaattaa
     2821 aaatgatact gaaactgctt atcagcactg cgaattatcc gcaaatagtg aagacttttt
     2881 agatttaagc taaaagttgg gaaaaaattg agttttaaaa cttacactct tcttatatag
     2941 aaaaggagag tgttttttat gattataaaa gcaaaacaat tatcaaaaat atatggttct
     3001 aataacaata aagttatcgc acttaataat gtaaatttag aaataaactc aggtgaattt
     3061 gtttctgtaa ttggaccttc tggaagtgga aaaagcacac ttttacatat tttaagtgga
     3121 ttagataatc ctacctctgg acaagtgtta cttgatgata aagatatata taaacacact
     3181 gaaaaagaac tatctgcact tagaagaaaa tcctttggat tcgtctttca acaatttaat
     3241 cttttacctg ttcttacagc atctgaaaat atttcaatgc ctgtacttct agataaaaaa
     3301 caacctgata aaggctattt aaatgaaatt tcatcattac ttggaattgc agatagactc
     3361 aatcatcttc cccatgaact ttcaggcggt cagcaacaaa gagttgcaat tgctagagca
     3421 cttattgcaa aaccagatat aatatttgct gatgagccta caggaaactt ggacagtaaa
     3481 agtggcagtg aagttatgaa tcttcttata aaaacttcaa aacagtttgg aaagacttta
     3541 gtggtaatta ctcatgatga tagaattgca aaacttgctg atagaaaaat ttcaattatt
     3601 gatggtgttc ttatggaggt gaaatagaaa tgaagaatta cctttcactt tcaataaaag
     3661 aattaaaaag ccagaaactt atgactacat tcatcattat agcaatagta ctatcaacta
     3721 ttatgacaac tgtggttgga cagtcaattg gtatcctaca aaatttaaga attgaacaag
     3781 cccgttcttt taatggtgat agacatgtat cctttcacca actcactaaa aatcaagttg
     3841 atgacataaa gaaagatgat agagtttatc aagctggtac ttcaataact attggcagta
     3901 gtaaaataaa ggattctggt atctctgtac ttgtaaaaga gtatgataaa acaggacttt
     3961 ctaactaccc caaattaatg aaattaaaat ctggacattt gcctaaagat aaaaacgaaa
     4021 tagccttaga tgaaaacaca ctaaagctta tgggtataaa accaagacta ggagtgacta
     4081 tacctatgaa tttagatatt tcacttttaa atgataccat accaccatat aattacacag
     4141 ctaactttaa attgagtggc attttagagg atgattatac aggatatgta agtggtatag
     4201 taaatggtat tgtaggtaaa ggtacatcag aaaatctatt acctaagaga tatattttat
     4261 cctctttgga ttttaaaata aaacagcaag aaaagtttca agaaatagta aatcaattag
     4321 ctaaaaaaat aaatctttct cacaattcaa ttcaatataa ttggatttac ttaaatgctc
     4381 ttaagataca gtttgaaaaa gatgaaaata gttctaatag tgatggtata tctatgatta
     4441 tattggtatc tttatttgtt gccttattgg ttttactggc ctctggactt gtaatctata
     4501 atattttaaa aatctctgtt acaaagaaaa ttaaagagta tggatgttta agagcaatag
     4561 gagctgaacc aaaccagata tataagatag ttattttaca aatcttaatt ttatgtactg
     4621 ttgccatacc tattggagct gtaattggaa ttatatcttc taaaggcata actggaatgg
     4681 tcactaatat cttaaatcca gatatacttc tagcaaatga taataaagaa attactgagc
     4741 ttatacataa aaatacaaca gcatatatgt tcccattagt attaagcact aatgtatctt
     4801 tgattttttc atttatttca gcattaccat cagcaatata tgcttcacat gtctctccca
     4861 aaattgctat ggttggtagt accaccaaaa tcaaaagaaa aattaaaaga gaaaaaacaa
     4921 taaaaaactt tgaaagacat ctagcatggc taaacttaaa aagaaataaa ggaagaacta
     4981 taataactat actatcatta tttatgagta taacagtatt cgttgcactg agtgagttct
     5041 ctaatgtatt agatgtatct aggtcagtaa gtaatttaaa agaaggagat ttttccttaa
     5101 caaatgaaat atctggtttt gataaatcaa cactagataa aataactaaa atgaaaaacg
     5161 tcaatcgcac ttcctttata aagtactctg aatacaaaca gggggaaata gatacagata
     5221 taaattttga aaatagtggt gagatgttaa aaatcattgg aattgatgag caaactttaa
     5281 aagacttaat gccttctatt acagattcta tactagaaga ctttaaaaat ggttctatct
     5341 gttttataaa aaatccgatt gctatttcta caccaggtgt aaaaactaga catacaaatt
     5401 taaaacctaa agatagtatc acaatcaaca aaaaacaact agatatatat agtacagtag
     5461 ataaaatgtt ctttttacaa ggtaatggct ggataaatgg tgttgatgtt attgtatatg
     5521 attctgttta taacaccttg acaaataaaa acaaattcaa ccagataaat atttatgcta
     5581 aagataaatc aaaattagaa caaataggat tgtctatcga acagatttgt gaaaataatc
     5641 ctggctctca ttggatatca tatattgaat cagataaaca acttaaagag agttttaaac
     5701 aaatagaatt tctagcatgg gcagttatat tatttgtggg attgattggt actttaaaca
     5761 tcattaacac aactcataca aatataaata ctaggactaa tgagattgga gttaaaagag
     5821 ctattggtat gagtaatagt agcttatata aaatgttttt atgggaaggt gtttattatg
     5881 gaatttttgc tgctatattt ggttcaattg ctgggtatgc cagtgctatt attataaaca
     5941 tggcaactat agaaaagctt gatttcacta atataccaat tacttcaatt ttacaagcta
     6001 ctattatttc tgtacttgca tgtattatag ctactcttat tccgttaaga aaagttaaaa
     6061 agatgaatat aattgactgt atagatatca atttataact attttacaga taataatata
     6121 aattaaatta tcaatgactg tctctatttt ctttcaaatc taactaataa atctttttaa
     6181 ctataatata agctttaaaa aaggcctgtc tcaaaataga gataagcctt ttttcattgt
     6241 cgaaataatg aaaatatatt taacttcaca aaaaaagagt gcctcacgaa ttaaaaattt
     6301 cgctttgaga cactcccctt taatttaaaa tatatagtta aatgctatgc caaaatttca
     6361 cacatgctcc acctgatttt gaattttcta ttttaacaga acctccaagc tgttccacta
     6421 attgtttgac aatgtaaagc ccaagaccag aatgtccacc ttttgtctgc ctagcttcat
     6481 ctcctcgata aaatttatca agagcctttt ttaaatcttt agagctaaac cctctaccag
     6541 aatcacaaat ctcataagaa atacaatttt tttcatcctt tacagtaata ctaatattac
     6601 cacctgatgg agtgtattgc agactgttgg atatgatatt atcaaaaatt cgtgtcaacc
     6661 tatccacgtc gatttgaatt ggggattgta tattcccctg cattttcaat ataagttcaa
     6721 cttccttttg atgagcctgt aattcatagt cttgcacctt ttgcctcaaa aattcaggta
     6781 aatttatagg aacaagattt aattgtatat ttgacttttc taagtcagac gtatattgca
     6841 tcttttggac aagagcagca cttttttctg tattttctct tatcactgta agatacctat
     6901 gaagtttttc attgtcatct gtattattac caataagtgc atctgtatat cccaaaataa
     6961 tagaaagagg agattttaaa tcatgtgcta gagcttccac catttcaaca cgttcctgct
     7021 ccatcttcca ctgtgcagat aaagagcctt ttaattcgtc tttcatttca gaaaaggcac
     7081 tacaaagttt accgagttca ttatctgaat aatagtcgat ttcaaaatca aggtcctttt
     7141 cttttatctt cttggacgca tcaatcaata gatgtaatgg ttgattgata ttctttacaa
     7201 agcgcttaga aagccatcta gtaaaaccca cgatatatag aaatggagaa aacagagcca
     7261 ttataataac tgcaaataca aatctccctc taatatttgc aaaggtgatt ttcacttggt
     7321 agaatagaat aacagcaccc tcaatctttc cattatcccc tttgattgga acagtatgga
     7381 tataaccacc tttacgaaca gttttattga tattattatt aaataattct tcttttgttt
     7441 taaatagttt tttggggtta gtaccatata aaatattgcc attattatcc acaacttgat
     7501 atagcatatc atccccacga atcgttcttt ttaaaccttc ttcattcgat tgtgataaca
     7561 aagctatgtt tttttcattg atgtattttt caattctagg aacttgtcgc tcataatagt
     7621 ttggtggata gatatcctta tttaaggaat gaatatacaa atagagagca aatacataag
     7681 taatcactgt ggcaactata ctggctatta taataaaaat aaaagtatgt ctaaattggg
     7741 taataaggga ttgatttttc atttaataac ctctctctct ttacatttta ttccacttat
     7801 acccaatacc ccaaactgtg gaaatatatt ctttttctgg tgtcacagca gaaaacttag
     7861 ctcgtatttt ttttactcgt tcaacaacag ttgaggaatc accttcagaa tcacaccccc
     7921 atactttttc atagatttgt tctcttgaga aaacttgtcc tgcatggagt gctagtaatt
     7981 caacaatatc atactctatt tttgttaaat caatattctt accatcaatt ttaattgcac
     8041 gttccttcat atataagcat aacttcccaa aatacaaagt agatctcttg ttctcttcat
     8101 tgatatactg tgaacgcttt tccctacgca gattagcttc aatccttgcc ataagttcac
     8161 gcagtccaaa tggctttgtt acataatcat cccctccaaa ggtcaaccct ttgattttgt
     8221 cggtttctga ttgctttgca cttaaaaata taattgggca taaaacatca tctctaattg
     8281 cctgacatac ctcaaatcca ttcattttag gcatcataat atccagtata ataaggtcag
     8341 gctcctgttt tgataactct atacctgcct gaccatcata agctatcaac acttcatgtc
     8401 cttttgcctt caattcatcc tcaagtagca ttactaggtc catttcatca tcaataatca
     8461 atattttact caatataaca ccacctttct cttatgggaa ggtcagtatt aaaacaatat
     8521 tcgtctactc ataacttttc cttccctccc acattttaaa ccaaataacg cctcctatca
     8581 agaatataat caaacctatt gctactacta taagctctat actagctgtt tgcatcactt
     8641 tagagtaaaa tgcctcagtt gaaatagttc cagcttcttt aataaaataa attcctggaa
     8701 gcatacctag ttttactggc catgtccatg gaacaaatgc ccatactttt tcaccaacgc
     8761 tagttaatcc aagtattgct gccatcaaaa ttccaccaat actaatacca atagatgcac
     8821 ccatacccca tgcaaaactc acccaaagat gaatagctaa tagtggaagt gtcccaatca
     8881 ccacaagtcc tgctgctgac aggaataacc atattgttgc tccagatggc actgcaatac
     8941 tcattcctat gcaaagtatc aacgtagcaa taaatgtgca tatagttagg caaaacagaa
     9001 gaaaaagaaa ttttcccaga tataatctga cacgagaaat acctacacat aaaaaaccat
     9061 taaaatttcc agcaagctct tcctcctgca ctataaatcc tgctaaaata cctactccaa
     9121 taggaatgat gaatacagtc catactgtaa aaaatccttc aaaagcaaat tcttgtgtac
     9181 ttccagattt agttgtgaga taaaaaacca cacataatga aaaaataata ggcatacaaa
     9241 gagtaagcca ctggacagct gtcctctttg ctcgaagcca ttctgatgat aatagtttta
     9301 tcatttgtca tccctcctat tgaaccaagc tgcagtaagt gctgttaata ctataaacac
     9361 aaccaaagaa acaacaatcc caataggaat cactgaagta ttcaaaagtg ggtctccagc
     9421 ttctaatata gtaccgttag gatgtatgtt gatgattggg cataccattc taactgccca
     9481 actccaaggt actgcaatcc aaaatggttt tgtcgcagca agaacaccaa atatcatacc
     9541 taaagctcca actcccatac ttaggaacat acctttccat gtagctagcc atagctgaag
     9601 tggaagtata gcaagagaaa caacccagca tacaatactt gcccctataa tctgtccaaa
     9661 aggaactgga ccagctttca atattaaacc agttataatt gttacgacta ttaaaactag
     9721 cgttgaaata aaactgtaga ctgccatagc tataacttta ttaatccaaa gtgtcatagg
     9781 agacacattg tgtgtacgta aagcacgata atttccagct tttttttcct ggaaagctac
     9841 caaagtagcg aacaatgcaa atccaatagg cagaaataaa aatgaccacc agttaaaaat
     9901 taatgctaaa agattttgcc acgcccaaga agttgtttga gataatggat tttgcatgag
     9961 tgttgattgc attataaatg catatgctgc aaaagacact gggaaaaaaa caataagttt
    10021 acccataaat gttcttttat actttaaaag ttctgattgt aaagcattca tctgttttgt
    10081 cctcctttaa gaataacatc tgtaaaaaat tcttctagat tttcattagg gtcaggcatt
    10141 ccttgaaata atagtcgtcc tccatttata attcctatat tatctacaac ttgagcaacc
    10201 tctgatagaa tatggctaga aagaattaca gttatacctt ttttgggaaa agaagcaatc
    10261 aattcacgca attcttgaat gccaaagggg tcaagaccat tggttggttc atctagtatt
    10321 aacaactctg ggtcactcaa aagtgcaata gctattccta acctttgttt catacccata
    10381 gaaaattgtg aagctctctt tttacctgta tttttcaaat ttactatttc caacacttca
    10441 taaattttat ctttaggtat tcccaatatt tttgtatgta ctaacaaatt ttcctctgct
    10501 gtaaggtttc catacaatgc aggggattct attaaagaac ctatttttgc aagagattct
    10561 cgtttccaag gctttctatc aaaaataata cgaccatttg ttgggcgaag aagaccaaca
    10621 agcattttaa gtgttgtgga ctttcctgct ccatttggtc ctaaaagtcc atatatacta
    10681 tttcgttcaa tttgtagaga aacattgtta actgccattt gttctccata tctttttgat
    10741 aagttttttg tttcaagaat taaatctttc atattaattt ctcccttctt gtaatacctt
    10801 aaatctgtta ctaagagaat actaacatga aaaaataaca attctataac acctactaat
    10861 tttaataaaa tttaaaataa aaaatagagt taccaatttt attttggcaa ctctatttaa
    10921 gtttatgttt tacagttata ttagatttaa gcttagtttc attatcacac taacttcaaa
    10981 tttactctat aatccttaaa tcaaacacta atttattaat caaacactaa tctattaatt
    11041 tatatttctt tagacatcta atatagtttg ctactaaata ataattattt atatcatatt
    11101 tatctaatcc tttaaaagaa gttatttcat cattaagctc atcactacct tctacaaaaa
    11161 cataacctgt ttcaaattcc atacctacaa taatcttaca gccactataa atttcctctt
    11221 gagtatcgta caattttttt gcatttcctt catttggaat tgtaaataca ataggtttta
    11281 attctttatc actggaaatc ttttgtgaaa aaggcttgtt taacttaata ttattgataa
    11341 ctacatgttt aaattcctct gaagtttctt ctactattac atattttcgc tttaaaaact
    11401 ctattatttc taaaacagac ttagaattta cttttaaaat acttttatat ttttcatata
    11461 aagatttcca ctgttcaatt ttttcctgtg gtatttcttg gatatgtgta cttatttttt
    11521 cttgagatat ttttttcaat taaactctcc tttcaatact taaatattct tatgaatctc
    11581 acatgactaa agttacaagg tttctactta atagaatttt gcatacttaa atatgtctta
    11641 ttaattctct acaggatatc tccgtagttc ctacaattct tacataagtt acttatttta
    11701 aattgttatt agttagattc taaaaattat ttattttatc actaatataa tactcttaaa
    11761 aactttacaa atcaatttaa atttgctacc ttttatttat aacaacttat agtacatttc
    11821 tcctatgctt ttcaatatat tacttttaaa aggaggtttt ccttatgatt ttaaatagag
    11881 ctgagctttt ccgaggatat tctttaaata gatttaacga gatatgcaat atattatcag
    11941 taaataaaat taaatataag tataaagtga aaaataatgc ttactctaaa aaaccttttt
    12001 ttaatgaaat aacacttggc aatttaggtc aaaaggaaga tttctcttat gagtacttaa
    12061 tttatgttca taaagacgat tatgaacagg cagagtctct aataaattct aagttgcgat
    12121 agattattta taaaacatga cattctgttg tcatgtttta tatgttatta tactttcaaa
    12181 tatgctacta tattttcaaa attgtgtgct ttaaaactag ctttttatag taatttaaag
    12241 cttaaaacta aggagactcg ttatatgaaa ataaatataa aatcaaagtt aagtgaattt
    12301 attaaacaga acaatctttt tgatgacagc agaataatat cctaccttcc taatataaca
    12361 atagaaacag acaaaataaa aactataatg attaatgagg ttgtcccaac taacaccaat
    12421 gacgattttt atagtgtaga taaagatgct gattatttaa aaactactat tcctttattt
    12481 gacagtgcag gaataaaagt atctaacata aatgatatcc tagatatggg tatctatata
    12541 actaatgcag taaaacttcc taaatcagaa tatacaataa ctcgtgatac aattaaatta
    12601 catatgccta ttttagaaga agaaattaaa ttatttaaaa acctagaggt agtaatgtta
    12661 atgggagatg ttgcaaaaaa atcttttaat atgattacta aaaagcatat aaaaaagaat
    12721 gtcatccctt ccatttcaac atataaactt cgtaataatg aactttatta tgataattta
    12781 agagtatttc catcatatat tatgactggt ggaaacatac tgattgaaaa atcaaaattt
    12841 gaaatggcat cagaagatat aaaaaaaatg ttcgagatta taaacggttg atattacaaa
    12901 ataataaaaa ctaatataaa ataaaagtgc atcaaaaact tctatttatg aggcactttt
    12961 attttatatt agtgtaacta tatactatta acataattta ttatttatat tgttcttttt
    13021 aatctctatt ccatttagtc taggtaacat tactctttac aagattactt tatatttctt
    13081 ttatatctct aacgttttta tttaataaaa caattattaa tacaagtcaa atatatctat
    13141 ttatctaaaa atatatcttt tacagtaata tctggatggt gatacttctt cctattcgtt
    13201 aaaaaagatt tttttacatt aatagcctct tttggacacc agtgaaaaca agctaggcat
    13261 ctttcacact cattacccca ctttggcttt ttatcaacta tacttatatt ctctacagga
    13321 caaacccttt tacatgtccc acatccatta catttatttt ctgcaaaaaa tttagtagtt
    13381 gcaatttgca tattcttacc tactaaacga agtacaacac tatctatatg tgactttaaa
    13441 ttgttttttc cttctatatt tccaatctcc aagttattga tacattttgc aatctcaact
    13501 accctattag tctgattttt caatctttct tcttcaacat ctggaggtgt tatcaaagca
    13561 tttccaggca tattgattaa aaaaccagca gataattttt tccccctttt tttaagtaac
    13621 ttatctatag taaataaact atgtccagct accccattac aagtggcaat ggcatatata
    13681 tgagtattaa tattaaaatt taatttctct acaaaagact ttactatatc aggaacatca
    13741 gcaaaataaa caggaaaaac aattaccaat atatcttcat ttatgtctat attattttct
    13801 tttctatgta tagctaaggg tataacttct ttacttccat ttaacgtttc ttttaaaata
    13861 tttgaaacta ctagcgaatt tcctgttcca gaaaaataat aaatcttact attcattctt
    13921 atccctcttt ctatatttct acatcatcaa tagttaaaaa gtctcttaaa ataggattta
    13981 tatttacttt ccaattctat ccaaaatatc agtaaacaaa ggcaattctt catcagagat
    14041 agatttaaat gtctctgttg catatatact tgcaatttca tttaatggtt cttctaattc
    14101 tctacctaaa tctgttagga atatttgaaa cttacgtcta tctttaacat ctactttacg
    14161 gacaattaat cccttatttt tcataacatc taagattctt gtcgtattag atttatcctt
    14221 acatgatttt tcacataaat ctatctgaga aattccatct tgctcccata gaaaccttaa
    14281 taacgcataa tggtcagttg ttatatcata tccattttgt ttaaacatct tttttaaatc
    14341 atcttttact tttaacgaag tacttactaa cttagttgta gcttcatata gtttctcaaa
    14401 atctttcatt ttacctccat ttaaataatc ccttgctcct cccatctatc aattattccc
    14461 ttatattgct caatatcttt aaaagccatt ggctttaaaa cagcatttat agcaataaaa
    14521 ttatagattt gagaaagcac aggtggattt ttcttttcct ctatgcaata aataaatttt
    14581 ttagatacct tttgtatctt tgattctact ttttcagtta taggattttg attaaatcca
    14641 gtttttatag ataaactacc acaaacataa cctcccgaat ctaagaccat ggattttata
    14701 aaagaaattg cttttgaacc acgtgcattt tcatatgtag taactgctat acatggctta
    14761 cgatacaata atctttcaag catcatatgt gctctatctg taaacacctt gaaaagtcca
    14821 gttacactac ttccataagt tgggctacca aatataacac catcactctt agtaattata
    14881 tcatgaatat actctacttt atcattttga ttgatacact tgcccatttt ataacaattt
    14941 aaacaaccaa tacaatatga tggatttacc ttacttaaat caaaataatt aatttttaca
    15001 tctggtatta atctttctat atctttatac aagtaagtta aaacttttga tgtagctcca
    15061 ttttttctag ggcttccatt tataactgta attatcattt ctatatctcc tttttagttg
    15121 ttatatcaac aataagtata tcaactatat ttttagctgt caatataaac catttattta
    15181 aagctatact tacacagctt aaataaaagt tttatttaac tacatgtgct tatttaatca
    15241 actataaatg aattattttt aataattgac aaactaaatt aatgataata tactttatgt
    15301 attacaaatg taagtagaag gaggtatagt atgaaaaagt taccacatat ttcagaagca
    15361 gaatatcaag ttatgaaaat tatttggaaa tatactccta tcagcactac tgaagtaatt
    15421 gaaaagttgg tagaaacaag tacatggagt cctaaaacaa ttcaaacaat gttattgaga
    15481 ttagttaaaa aaggagcttt aacatatgaa aaaaatagca gagtattcgt ttatactcca
    15541 cttgttaaag aagaagaata cgtagctaaa gaaagtagtt cttttttaaa tcgtttttat
    15601 aatggtactc ttaattctat ggtactaaac tttttagaaa atgataaact atctgaagat
    15661 gatattgagg aactgagaga aatcttaaat aaaaggacga ctaaggggga taaataaata
    15721 tgtatgcccc attctttata cgatttttac tcagtacatt aaccttatca atattaattg
    15781 ctgtaatttt acttgccaaa aaagtattta aaaaacatat ttctgcaaag taccaataca
    15841 atattggatt tatattgctt ataatgttaa taattccatt tgtccctctt aaatatatta
    15901 atcttggaaa tgtatttaac tatttatata cttttaatca acttggaagc agtactaata
    15961 ggacttctat gataaaaaat agtccaaatt ctataattaa taactcaaat gcattaaacg
    16021 atttttcagt atccctaaac caagttaatt ttgatagttt aaatatttta ttactaatat
    16081 catggataat tggaatttta atcatgatag ctattactat tcattgcaac attaaaataa
    16141 aaaatatgaa aaaatcaata caaattttaa gagatgagga gatagtattt atatttgaaa
    16201 agtgtaaaaa agatattggt ataaataagg attttatact atgcaaatca cctattataa
    16261 atacacctat tacatttgga tactttaaac cacacattat attaccagat aagtctatat
    16321 ctaaattatc tttaaaagat ataaaatata tcttacttca tgaattacaa cactttaaaa
    16381 ataaagatat actgataaat tatataatgt gcttccttca aatattatat tggtttaatc
    16441 ctcttgtatg gtatgcattt aaagaaatgc gtatagaccg tgaaattgca tgtgatattt
    16501 cagttttaaa aaagcttgat aaagatagtc atatagaata tggacaaact ctaataaact
    16561 ttgtggataa tatttcaaga ccatcaaatc ttacacttac atcagatatt ggtgggtcaa
    16621 aaaaacaaat aaaaaagcga ctattgaaga taatggattt tcataatgaa tcaaatacgt
    16681 taaaattcaa aagcatttta atttttacat tgatagcttt aattgtattt ggaaatattc
    16741 ccaaactatc tattatggca gatatcaacg aaaaatatag acctacaaat gaacaaactg
    16801 tgtacgagga cttaagtcag tattttaaag gttttgatgg aagttttgtt atgtatgatt
    16861 taaaatccaa gcaatatcat atttacaata aagaaaaaag taaaacaaga atttctccaa
    16921 attctactta taagatttat agtgccttat tgggattgga aaatgggata ataacaagaa
    16981 ataattcaca tatcccttgg gatggaaagc atcattctaa tagttcttgg aatgaagacc
    17041 aagacttatt ttctgctatg gaaaactccg taaactggta ctttcagact ctagataaaa
    17101 aaacagggct aaaaaacata caaacttatc ttaggcaaat tggatatggc aattatgatg
    17161 tttcaggtgg tatctcaaac ttttggctag aatcttcatt aaaaatatca cctattgaac
    17221 aggtagaatt acttgaaagt ttttatacaa ataagtttaa atttgaagat aaaaatatag
    17281 aaacagtaaa agattcattg ttaatatcaa aaaaggatgg ggtatcactt tttggtaaaa
    17341 caggcactgc taatataaat ggaaaagatg taaatggttg gtttataggt tatgtggaaa
    17401 aaaatgaaaa tacttatttc tttgctacaa atattcaaag caaagattat tctaatagta
    17461 gttcagcatc taagataaca ttatccatat taaatgacaa aaaaatctat aatccttaat
    17521 atatttactg tacattctaa aaaattcaca taattttcat attaattatc aattaaattc
    17581 atatacaagg cttattatat aaacatagaa gatagtaaaa ctagcttaaa aacataatat
    17641 aataccctat acaaatagtg gcaactctcc ctcacatcct caattgttgc cactatttaa
    17701 ttttttgtat gaagttaaat atattttcat catttcaaca ataaaaaaga ggtctatctc
    17761 tattttgaaa caacctcttt aattatttta gagtttacta agaagtctaa aaacaattta
    17821 tctaaaatat tattctcaac tgagtaagat taatttccaa attgagtaaa tttaatcttc
    17881 aaacactgat ttaacaatag gaataacata atgacttccc ccacgactct ttacatcttc
    17941 aatcatagca attactatat attgtttatc actattttca tctacagtaa aagcattaaa
    18001 ccatccaagt tctgtccctg taacatcatc ttttgatgct ttaatttctg ctgtaccagt
    18061 tttcccagca atgctaattc ctttaatcat agcactatga cctgtaccat cagggctttc
    18121 aacaacttga agtaagtcat cacgaataat ttttacagcc tctttagaaa acacaccttt
    18181 cttccaaaat tcagcctttt taaattcaag atggggtttt atcatgtctc catcatttac
    18241 aaaagctgaa tatattgatg ccgtatgtac tggatttaca agaagcttac cttgtccata
    18301 gccagtatct gctaattgta tttcagtctc aaatttattg tcagtgccaa attttgaaga
    18361 agacaatcca aattcaaatg gcatactttc atcaaatcca agcttcagca actcttttgc
    18421 taatacatct tcacctattt ttaaggctgc cttagcaaaa taaatattgt cagaataaat
    18481 caaagcattt ttcatatttg cagtatttcc ataatctttt aacgtggtta ccttataact
    18541 tccccaacta gaatcttttt gccaacttag actgctgtgt ccaaagtttt catttggatt
    18601 aatctttcct gttgttatac caataccagc agtaactggt ttaaaagaag acccaggaca
    18661 taatcgtgct ttaaatctat tgtacattgg tttattttca tttttattga gttcattcca
    18721 tctatcttct gacattccca atataaactc atttggattg tacgacggac tacttacaag
    18781 tgataaaacc tctcctgttt taggattcat aactactgca caacctttat catttttcat
    18841 ttggtcatat agtttactct gtagttttga atctatagtt agctttacat cttctccatc
    18901 tacctttggc tcagttacta aagtttcttt cttgtcacca tatctatcag ctattataat
    18961 ctcatatcca tcaataccac gtattctatc ttccagtaaa ttttctaaac caatcttacc
    19021 aattatacta ttatcgttgt acctcttacc ctctttttcc tttagtatat ctgcatttac
    19081 attttgaaca taaccagtta aatgaccggt tttttcacca aatggatata ctctaacctc
    19141 tgtattagat attttaactc caggaatact aagaagtgac tcttgtagtt ccttatcttc
    19201 ttcttttaca gtaccatctg tattttcttt tattttttca atagttttta taggtaccat
    19261 tgaattttct tttacccaag atgcatttaa tttcttttca atttgttcaa ctgatacatt
    19321 caataaagta gataattttt ttaagtcttc tatattatca ctcatttttc caggaactaa
    19381 tcctatcata gatgcaagac cttgaccagc aatcattaca ccgttcctat ccaggatacg
    19441 tcctctctta cctttcagct ttgataccct tacagtatta tcttcttcaa gttctggaaa
    19501 tatgacgttt gactgccatt ttattttata atttttctgt ctatctctag ttaatagtac
    19561 ttcatttgaa aatgaaattt cacctgctaa agtatccatc ttagaatcat agtttattac
    19621 tttatcatta tttttatttt ttttaatatc attaatctta atacttatat cgtgtgcatc
    19681 aattccttca tagatttttt tatttcttaa aacaaaatct tcttttttat tttcagactt
    19741 gctcttttca tctaataaat catacatttt ctcatattgt tttttatttg caaaagacat
    19801 atactgctta aacacttcat ctggtttgtt tttattgagt ccatctagta tgaattttgc
    19861 taaaaaaaca ataataacta taagcagaca cattagaaaa ccaaaaatta tcatttttct
    19921 tgttttttta ttttttctca tataaaccac ctttatcatt taatatatta catacgtaag
    19981 ctttaaggtt aaaatactct tatagacata actaatctat gtttttatta tgtttttaag
    20041 tatctcataa aaatatgtaa gcagtataat tgatagtaac ttatatatta cacatgtaag
    20101 ttttaaaagt caataatatt atcattattt aattattttt tacatcaact taaaaataaa
    20161 tcagttccat tatattcttt tgtattcttc aactatttta taaattaacc ttattctatt
    20221 gtaattattt tatagtatat aactttaact tgacaaaacg acacaagtgt ctcataatta
    20281 aaagtgacac ttatgtcgtt aaaaaggagg ttaaaacata tgccaacaaa aggagaacaa
    20341 actaaacaat ttatcattga tacatcaata atgctatttt ctgaaaaagg atatagtaat
    20401 gtgacaatga aagatatatg tgaagcatgt aatttaagcc gtggtggcct atatagacac
    20461 tttaattcac caaaagaaat ttttatcagt atattaaaca ctcataaata ctactctcaa
    20521 aatttgttgg ataaaggtat caaggaaaat atatcagcta agcatatgct agaatatttt
    20581 ttccaacaac aaaaggctga cataaatggc aaatattgtg gatttgattt tgcaatacac
    20641 gaatttgctt ttgtagaaaa agaccaacgt gattatatga ataaaagata cagttcagct
    20701 atcacaatgc tttcaaattt aatcgattat ggacaatcta aaagtgaatt taaaaaatgt
    20761 gattctaaat cagttgcaat acacataatg ttcttatttg atagcatgaa aacatctgct
    20821 tccattttga aacttacaaa taaagacatt gataatcaaa taaatattat aaaggacatg
    20881 gtgattttat atgaataaac aaaaattcca taaaattaat ttacaaaact gggaacgata
    20941 tacacatttt tactactttt caaaaatgac aaatgtaggg tttaatttga ctatagaaat
    21001 agatattact aatttgctta aggaaacgaa aaaaagaaat attaaatttt atccagcgta
    21061 tttatataca ataactactt gcttaaatcg atatagagaa ctaaaaatcg catatgatga
    21121 agatgaactc ggatattgga acacgttaac gccactttat gcgatttttc atgatgataa
    21181 taagactttc tcatcaatat ggacagaata tgatgaaaat ttctcaatat tctatgaaaa
    21241 ttatttagct gatgttaaag aatatggaaa aaatcatggt tttctagcaa aaccaaatcc
    21301 gccaagaaac tgctatactg tttcctgcct tccatggatt agctttaaga gttttactgt
    21361 acataatcat ggtcttgaaa attatttttt ccctacaatt gaagcaggta aatactatca
    21421 aaaagatgaa aaaatacttc ttcctctttc tataacagtg catcacgcaa ctactgatgg
    21481 ataccatgta agttgtttta ttgattacat acaaaaaatg tgctttaata ctaagatatg
    21541 gctacactaa aaatttatac aatataaaaa gaactgtcgc atgagcaaat taaatttgct
    21601 atgagaaagc tcttttttac ttacaatagt taatatgaga tgaattattt cttatacttt
    21661 gaacttacca atagttaata tgaaatgaat tatttctcat actttaaaaa gattgaatta
    21721 ctcttgataa tcttcttttg tagtcattac atatcaccta ctactcaaca catattcttt
    21781 gacctatttt tacatccttg tttatatcca aaatatttac cttcttacca tctggaaaca
    21841 ataccattgt taaagtagac tttcctaatt cgtgtattct ctttaaatca acattaacaa
    21901 gaacgtctcc ctgtttaacc atatctcctt gtttaacagc aacatcaaag ccatctccat
    21961 ttaatgcaac tgtatcaatt ccaacatgaa ttaatacttc tccattagtt cctttaatcc
    22021 caaatgcatg tccacttgaa aatactgttt ctaatttacc tgaaatagga gaaacaattt
    22081 ttccatctat aatatcaata gcaaaaccat cacctaacat ttttttagaa aatgtttcat
    22141 ctggtacatt ttctaatgca acaattttcc ccttagctgg agacacaaag ttttcattat
    22201 tttcattaaa cactaattct tcgtcttcat cttcatttat agcttcttta ggcactccaa
    22261 ataaacatgt tacaataaag cagaatgcaa ccacaaatat tgatactaat aagtatgtga
    22321 ttaaattata tccatcatag atatacatta aataagaagg taaaactgct aatccatatg
    22381 aattagattg aatatgtaaa attgataata ttgctgctcc taaacctgaa gatgcacaca
    22441 taataatcaa aggctttaaa ttatatcgaa gctgaatccc aaataaaaca ggctcactta
    22501 taccaaaaag ttgagatagc attgctccaa ctgcagtttg tttaacttga ttatttttag
    22561 attttttcat aaatgctaga catgttccaa tattcgcaaa tccatacatt gcacaaagag
    22621 taataagggc attaaatcct gtatttgcta atagtgatgt ttcaatcatt acataagtat
    22681 gatgtaagcc agtaataaca gctaatggat atgtaaatcc aataataaat cctccaattc
    22741 ctaaaggcaa atcaatcaat aagctgatga tatcaaccat ttttaattct attgtatgca
    22801 ttatagggcc tacacctaat aaaataacta acattgttat tagcataaca aagaatggtg
    22861 tgaaaataag gtctaataca ttaggcatat gtttacggaa ccatttttca agattagctc
    22921 caataaatgc tgtaacaata gctgttaaaa cacttccttg acaacctaca ataggaataa
    22981 atccaaatgc cataattgct tcaatttcat ttgatgggtc agcaacagaa tatgcattag
    23041 gaagtattgg ggaaactaac ataagtccaa taacaagtcc aataacaggt gttcctccaa
    23101 atactttaaa tgctgaccat acaataattg ctggtaaaaa agcaaatgct gtttctgtaa
    23161 gaaccgaaac aagtgtctga atatacaatg gaatatttgc agaagacatt ccaaataatc
    23221 caagtacatt atcattaaac aaacaaccct ttaatcccaa gaataatcct gttgctgcaa
    23281 taactggaat aataggaaca aatatatctg ctagagttct cataactttc ttaaatccag
    23341 tttcattatt tttaactaat tcatcttgtt ctttttttga taaagttttt aatcccattt
    23401 tttcaacttc tgcataaact ttattaacta ttcctgttcc taaaataatt tgatactgtc
    23461 cagaagtaaa gaaaacacct ttaacctcat tgaccttttc cactttctta tcattaatag
    23521 tttccctatc tttaatcatc acccttagtc ttgttgcaca atgtgtaata gaaataatat
    23581 tatcttcacc aataatttta ataagctcat ttgctatttt attatattta ttcatttttc
    23641 tacctcgctt tcaataatac tgcatgaaat ggtttcaaac acactgtttt atttaataga
    23701 tttatatcat ctaaattttg gaatacaata tcatattttt cttctactct tatttctaca
    23761 ggtttatcag aaaaattata ataacaatca ataactacca aatctaattg ccttctatac
    23821 gcaataacat cttcactttc tatatcaata ggttctattg aaccataaat caaacaatca
    23881 gaatactcac tatcttgtct caactttatc atctttttat aaaattctaa aatactctct
    23941 gaattgttaa tctgactctg tgcattaata tctttataat tttcaataac ctttaaccat
    24001 ggtgttgtat ctgaaaaacc tgcattttct ttatctgccc atggaaatgg cgttcttgca
    24061 ttatctcggc ttcttaaatt cacaaattct aacgcttctt cttctgagta accttcatct
    24121 attgaacgat agtattggtc aatgctagat aaatcattaa aatcatttat ggtatctctt
    24181 ttaaaatttg tcattcctaa ttcctgcccc tgataaataa atggggttcc tcttaaaaag
    24241 aaatacattg ctcccaacat ttttactgca tcatcattcc tttcgtattg caaaagatac
    24301 tttgttgtag ctcttggttg gtcatgattt tcaataaaat tagctgccca tccatgttcc
    24361 tgaacataca tttgactatc taaaatgcat tttcttaaat ctggaattgt ccatgaaatt
    24421 cttttaaacc actcactacc agaagcaaca tctaagtcag catgtttaaa gtcaaagacc
    24481 attgaaaaga aaccatcttc tccaataaaa tcacctaact ggtcatagct aatacctgct
    24541 gcttcagcaa cagtcataca atcatatttt ttaaacgtat tttcttttaa ttcataaagc
    24601 attttttcta ttccaggctg atttctaact gtttttgtac atttaacaag accatcaaca
    24661 ccatcacttt ctaaactttg aaaacttaaa ttctttttga tgaatgtaat agcatcaact
    24721 ctaaatcctg ccactcccat ttgagaccag gtattaatca tttggtaaag ttcacttctt
    24781 aatattggat tttcccaatt aaggtcaggt tgttttttac caaaagaatg aaaataatat
    24841 tcgtctctat tctctacctt ttcccaaaca cttccaccaa aaacagacct ccagttattt
    24901 ggtaaatcgt ttcctttttt aaaaatataa taatcatgat aaggactttc tggatttttt
    24961 aatgcttctt gaaaccaagg atgttcatca cttgtatggt taagaactaa atctaatata
    25021 attttgattc ctctatcttt actttcttta attaactctt ttaaatcttc catacttcca
    25081 aattcacttg caatatccaa ataatcacta atatcatacc cattatcgtc cataggtgat
    25141 ttaaaaattg gacataacca caatgatgta atacctaaat cttttaaata atctaaacga
    25201 gaaataattc cctgtaaatc tccaattcca tcattattac tatcttgaaa gcttcttgga
    25261 taaatttgat aaacgatttc tttttgccac catttctttt ccataaatta ctccttttta
    25321 tatgatattt cttcttttta attctttata aattccatta tcgaatatgt cctcacatat
    25381 agatgtcgct atatctttaa gttgttgatg actatttttc attgcaattg taacgtctga
    25441 tgcttgaaac atgacaatgt cattttgacc atcaccaaaa catatggttt ctttttgagt
    25501 tactcctaat ctttcttgta atctcttaat tgctttgccc ttatgaaaat ctttttgaat
    25561 aatttcataa tactgactag aaatatctct ctgtgctaat tccattttat cttgtagtat
    25621 atctttcact tcgtcaaata ccttttcatt tgaccataaa caaattttat gtatatcttg
    25681 tgacttatac tcttcaatgt tattttcata tgttattttt tcttggatat gttgtttatt
    25741 tatacaagaa ttagttcctt tcaactgatt cattgtttca aatatttctt tggctttttg
    25801 attcatgaaa actttttcct gactctcaat cgaaaaagca acttccctct tttttaataa
    25861 acaaacaact tcctttatca atctttgatt aaaagattga ttataaagta attcaccatg
    25921 atattgaatg taattacctc ctcctgcaat atatccatca actcctaatg ataaaacatc
    25981 atcttgtatt gtacccatac ttcttccagt acaaataaca acactacaat gattcttttg
    26041 acataaacgt atagcatgct ttgcagattc tgggattcca tatacctcat ctctaagcgt
    26101 accatctata tcaagtatta ataatttgta caatttcatc ttcctttctt actatcaaaa
    26161 tcataatagc attcaaaaaa aaagatatca atattttgat atcttttaaa aaatatgttc
    26221 atttttagca caaattttca ttttcgggga atatgttcac tttctaaata catcttgtat
    26281 ttaatataaa gcagttcaat taaaataaaa taaggtgttg ttacatcgta gtccagttgt
    26341 ttatctacag aaatagatat agattgaata tacaggtttt catcacataa tcttgctaaa
    26401 ggattactta tcatttttgt aatagaaacc atataaattc ctttcattct catttcttta
    26461 gcaaaatcaa taattgtaga tgcatctcca ttcaatgaaa taaagaaaat catatcatct
    26521 gtttttataa aatgattaag tgcctgaatc atatcataac cataaacatc atatataatt
    26581 ttccctgttg gtaagaaaat ccttttcatc tctttagcaa ctctttcctg agaataacct
    26641 tctccaaaga cgattatacg atttgccttt ttcattcttt caaacataat cgaacaatcc
    26701 ttcttctcta tatcatctat caccttatta taacaatcca ttaattggtg tttactttga
    26761 tttttatatt ctacttctgt ttcatttaag cgtataataa ctcttaattc actatatcca
    26821 ggtaattgta gtttttgagc aaaacgagaa agtgcacttg tagatatatg gtatttgtct
    26881 gcaaattcat ctatagaaag tttaatacaa tcttctttat gattaagaat acactcacag
    26941 atatacttat catttgctgt aaatgaatta taatatttat tgaaaagtcc ttcaattttc
    27001 attcttttct ccttctatac tctatgtaat tcatatgaag caaatctaat agagcataaa
    27061 atgctcctac gacttcataa gatatagctt gtaatgtatc aagtttttga gtttcaacat
    27121 acagattata ctcacaaagt gttgcaattg tattattatc aagcctagtt aaagaaatcg
    27181 tatgtatatg attgttgata aattttgcaa tttcaattcc tgcttttgtt tctccagata
    27241 aagaaataat aataaataaa tcactttttt gaaatgattc tctcataaat tcaatttcac
    27301 ctatatcaaa taagtcaata acacatttac ctactgaaag aaatattctc tttatttctt
    27361 gagctaaact tttctgttca ttacctgtcc cataaatata aattgtttct gcatcatata
    27421 ttattttaca aatatcttga aatgatattt tttgtaattc attcattaat agtcgataat
    27481 tctcgcaaac atcatgaaaa ttattatcat tattaacaaa ttctagttga ttatttttaa
    27541 gtaaatactt taaatcagag aatgaatcta atccaatttt tctacaaagc cttaataaag
    27601 tagctctaga aacattacat tcatttgcaa ttttttcaca cgaaaaatta cggtattctc
    27661 tttgacaaat caatatttgt ttaataataa ttttatcatt ttcatttaaa ttatcataat
    27721 tttggttaac taacgattct aatctcattt tttccactcc ctaaatatta ttttaatata
    27781 cattagttgc tttttctagg gaagagtttt aaataataag gataaaataa tcatttgatt
    27841 ttatttttat taaaataaaa ataacctgct aaaagcaggc accaaaaagt acttatcctt
    27901 tcgaacatgt actttagata ttgctttctt cggaagcttc atctcttcat actctaaaat
    27961 agagtttttt ctaactcaaa agtattttcc atggtagaaa ttactttaat tcatctgcca
    28021 tttatttttt atcttattta ataattacta ctacttgaat atttacttct ttaagtaaat
    28081 ttcatagtta acaaagctaa aactattatt atagatgtta aaatacaaaa ttgtaagtat
    28141 tgttataaat atgcttacag ctacaaatat acatgatata ttaaaaagaa gctgtaaatt
    28201 attatcatac atacaagcaa ctacgcctct attaatccat gttaattttt attatttaat
    28261 acaaggagtt ccatgagaca tacatatcca ttcatatttt aaattatcca attctcttat
    28321 agatttcatc atctttttat aatcccaatt ccatggatta ggataaggaa ctatatttcc
    28381 attcttattt ttgactaaat cacctgcaaa taatacatct tcaaaaatca tgcagacatg
    28441 ccctggagta tgaccaggag tatggataat ttttatattc ccaatctgca tattctctcc
    28501 ataaggttca acatccttaa tgagccttct ggaaattgcc tttccaataa acttcttaaa
    28561 cccaggtcta tccttctctc ctataataaa aggtatatcc tctacatgag cccatacttt
    28621 tgctcctgtt ttttctttca ataatttaat attagatata tggtcaacat catgatgagt
    28681 taataaaata tgcttaatat ctgtaagttt aataccaagt gtttttaatt ctttaattat
    28741 atttttcccc ataaaaggaa gacctgtgtc tataagaata atttctttat caaacacaat
    28801 aaaacaattt gagccacgag tactatctaa cattaataca ttttctttta tcttcataaa
    28861 taaattcccc ttatttggta ttttacctat ataattaatt aataaagtta taaatagtta
    28921 taatacttga tattaatttt attttttatt aaagtatact ataggtatac aagtattata
    28981 tttacataag tataccatca gtatactttt ttatcaatag aaaggaataa tttatatgtc
    29041 agaattatca aaaagagata aagaaaaaat acaaagagaa aatgagatta ttgataaggc
    29101 agaaaaatta ttttgtctta atggatttga taatacaact atgaatgaat tagcaaaaga
    29161 agttgaatat actaaacgca ccatatacaa gtacttttca tgtaaagaag atttattctt
    29221 tgctgttgtc ttaagaggat ataaaagact ttgggataat gttaaaatag aaagtgcaaa
    29281 aggcaaaaca gggtttgaaa aaataaaact ttcatacttt gcttttcata aattttactc
    29341 tgtagaacct tctctattat gccttatggg aatgattggt attgtaaact ctgaaaaatc
    29401 ggatactgat atgctgttta aagaaaagtt tttttctttt aataaattta tgtttgatga
    29461 aatacaagga atgtttgaaa ttggaaaaaa tgatagaagt attaggcatg atattgaaat
    29521 acctactctt atgtattcat caatatttac acttacagga ttttttaatt tactatctgt
    29581 aataggaaaa tcatacctga acaactttaa tatagatgag gaaaaattta ttgaaacaac
    29641 tcttgctctt ttaatagatt caattaaagc ataaacctaa gtttataaat taaagtttat
    29701 atacttaaat ttaaatgata attttttcta tctctaatat aaaaaatatt aaacataaaa
    29761 ctaataactt agttaatgga ataactaaat tactgaaagg attaaaagta aatggctaaa
    29821 atacttcttt tagaagatga tgatacaatt acatttggaa taaaaacttc ccttgaaaag
    29881 aaaaatcaca ctgtatgttg ttataatacg attgctgaag ctaaaaaaaa ttttgataaa
    29941 actattgatt taattctgct tgatttaaat ctacctgatg gtattggata cgagttttgc
    30001 caatatgtta aaagtataga agatactcca gtgatatttt tgacagtccg tgatgatgaa
    30061 aaagacatta tacgtggatt agatatgggt gcagatgact atgtggttaa accgtttttg
    30121 ctctcagtac ttcaatccag aattaatgca gttcttagaa gaactcattc aaatactaac
    30181 aatactatta catgtgaaaa tataagcttg aataaggttg aagtcaaagc atatttagat
    30241 aatgttgaag tacctttgac agcaggagaa tataaacttc ttctaagtct tatggaaaat
    30301 aaaaatagag ctatgactcg tacaaagtta ctagaaatgc tctgggatgt agatggtaat
    30361 ttcgtaaatg ataacactct tactgttaca ataaaacgtc ttagagaaaa attaaaaaat
    30421 ccaccttgta taaaaacatt aagaggcata ggatatagaa tggaggacaa ctagtgaaaa
    30481 ctccaagaaa tatcaacagt acagttgttt ttataatatt ctgcttaatt gtaacttttt
    30541 tattgagtgt aattctaaca actataactt cttttaatga atacaatgta ctgtctaagg
    30601 ctcttggtgc atcatatgag tacaatccta agtctacaga aagtatacta aaatcactga
    30661 aaaattctag tgataaggat tttaaaacag gaaatgaaat tttatcaaaa catggatatt
    30721 ctaaaagtac actttggagt aaaaactttt tttattttct agtgatatcg tttggtataa
    30781 tttcaacaat ggctacagtt gtatatataa tcaaacatag aacaaataag caaaaactga
    30841 gtagaataaa caatcttact caatacttag aagaagtgaa tttaggaaaa gagtctgtac
    30901 ttttacgatg tgaagatgaa ttttctcacc ttgaagatga gatatataaa acagttgggg
    30961 aacttcgttg ttcaaaagaa tttgctttaa aagaaagaca aactctttca gataatcttg
    31021 cagatattgc tcatcaactt aagactccaa ttacttctat gtcacttatg gcacaattac
    31081 tttcagaaaa ttgtccagat gaagaaatag attatattaa caggcttaca aatcaaatct
    31141 caagacttga gagactagtt tcatctttac ttacattatc aaaattggat gcaagtactt
    31201 taatatttga aagcaaactt atagatgtac attctcttct tacttatgca attgagccta
    31261 tagaaggttc tttaagagaa aaacatcaga catttactat cgaggcttct ccttcggtag
    31321 aatttgaaat cgatattaat tggactttag aagctctttt aaatattctt aaaaattgta
    31381 gtgagcatat agaagatggt ggatatatag ttgcttatta tagtcaaaat cctctatatg
    31441 ttgagattat catagaagat aatggtaagg ggtttgctca ggaagaactt ccatatattt
    31501 ttaatagatt ttatcgtggt aaaaatgcta gtaaggacag tattggtata gggcttgctc
    31561 tatcaaagtc tattatagaa cgtcaaaatg gtactctaca tgcagaaaat tgccataatg
    31621 gtggtgcaaa attcataatt aaattttaca cataaaatgc tggattatag gtaaaatacc
    31681 tataatccag ctatatctat attctatgtt atctattgtt ttagtaatat acttctattt
    31741 acatttaagg ttttattaaa caaacaaatt aactatccct atacttgtaa gtagtcttaa
    31801 atcgaaacct ttaaataagt tcaaatagat tttgtttata ttgtttcatt ttttatagat
    31861 tctactatat tttcattctt caactgcttg tatcctgtca tatatgatgc tattacaata
    31921 aaaagtatca atatagtaaa acctattatt gtagatatag gtgcaaatgg taaatactct
    31981 ataaaatata tttcatttat acgtagaaaa gcatacacta ttcctatttg cacaggaata
    32041 ctaagtagta atggtgtaat tcctaagaat aaaccttcca aaataagcat cttttttatg
    32101 ccttctggag ataatccaac agaacgcaac atagcaaact cttgtcgtct acttctaata
    32161 tttcctgaca ctgtagcaag tacatttgat aatccaatca tagccaataa acctgtaata
    32221 aagcctacta ttaaattcat ggtctttatt ccactagcct tttgtttttc actttctaaa
    32281 acatcctcaa tactataatc tcctgaacca tagtctttat tataaatgga ctctaatttt
    32341 tctcttactc taggaatgtc ctcacgatta tttactttaa atactcctat cagcctattt
    32401 gaacgtaacc tacttacttc atcataattt ttagatattt cctgcaccat agacattggc
    32461 actatttgca ttaatgtata ttttgaacta gtatctacta ttttaggaag tgtgcttgta
    32521 atagctccca ctttcatgtt gtaagtataa tcccctttat cttcgtcata tactttttca
    32581 tttaatttaa tgttatctcc tattgaaaga tttaaataat ctatatatac tttatttcta
    32641 cgtgtactac gattaatatc ttcctcctta ttatatacaa ttgaggttgg attttttgta
    32701 tcataaaata actttgggtc tacagaaatt tgcctacaat attctgtaaa actcttatca
    32761 tcaagcccaa ttatatttga aattatacga aacttgccat cacgttctat aggagagtat
    32821 tttttagatg aaactatact tttaaatcct ccatttttcg caagttcttt tgatgcatct
    32881 ttttcagtca gccaagtgga agcagatatt ttttgataat atagtgaact ttttacacct
    32941 tctgtattat ctaatttttc aatgaaagca gactctacag gttcactatt ttccaaataa
    33001 actgctatat ctctttggtc cttataatta tcacttccat aaacagcttt tgctccttct
    33061 tgatttgcaa ttatatgcaa aaaacatgta agtaataaaa aagataatgt taaagatatt
    33121 gttgcagtac gataagattt tttacgagca cgtagtgcgt ttgatgcaag ttctccttct
    33181 attccaaata tctttcctaa tgaatattta tgcgactttt tgattttaac actatctcct
    33241 tgtcgtattg cttctatagg agatatcttt gatacttttc gtgctggtat aagtgcagaa
    33301 atccagactg ttactattgt aagtaaaact gctggcagaa aagcaggaat accataagta
    33361 aataccactt ctggaacatc agtatgataa ttaactgaat taacataaac tataagccta
    33421 ttacacaata accatcctaa aaataaacct attggtaatg gtataattgt cagtaaaaat
    33481 ccttcaaaca ctacagacct tttaatttgt tttggtgatg caccaacact agataatatc
    33541 cctaactgag taagtctagc atttgcagac agtgaaaacg cgttgtaaat caccattaca
    33601 aacacggcta ctgtaaaaat tgctattgta agatacataa taggagttga aaattttgat
    33661 atactactca tagatgcttt ctgttctggt gaaaagacta acatctttaa aagataatta
    33721 ctattgtatt taagattgta ttttccatat tcattagtct tccaccccaa tgatttagca
    33781 agttttggaa gttccttata cgtgtctctt atatttttaa atcgcaagta cacagttata
    33841 ctatcattag gttttatact tgttttatca agatatccaa gagctgtata tgcaggtatt
    33901 actgatgaag tagaaacatc tacctttcct actattgtca atgtagtctc tgaaattttt
    33961 ttaaaacttt cccctttcga ttttggggct atgggttcaa gaggctttcc atttaggatt
    34021 ctatctccta ttgggagagt aattttatca ccaattttta cacttggatt attctcaaaa
    34081 tattgttttg ataatgcaat ttcattagca ttatttggtc gacgaccctc tattatagta
    34141 tccttttctg gcatagaatc ccaatactct gatgtagcat ttctataaat tatataatct
    34201 cttttctcat cattaatttt gcctacatac cattgtcctt ttaccattac atcatcaact
    34261 gaagaaaaat tttcaattaa tggtaagtca cttccataag tatagtcaaa caattcacca
    34321 tgccagttac cttctttctc aattgaaagt cttataaaat ctgtccacat ggtatacaac
    34381 agtccacaca aagaagacat catggttgta gtaagtaata tagctaacat tatagctata
    34441 ctactacgtt tattgcgtcg tacaaagtct aaggtgtatt cttgaagaat attcatttct
    34501 tcaccacctt ttcagagaca atcactccat cttccatagt tacaatacga tttgcctcta
    34561 gtgctatttt ctcatcatga gtaataagaa gtattgtctg attaaatcgt ttatttgata
    34621 agtttaacaa atctacaatt tcttctgaat tttttctatc gagattacca gttggctcat
    34681 ctgctaataa aatagctggt ctataaatta aacttctagc tatagatacc ctttgttgtt
    34741 gtccacctga aagttgactt ggaagatggt ttaatctatc agataatccc aatatagata
    34801 caatctcaga gaatctatcc tcatccacct ttcttttatc aagtaacatg ggtaataata
    34861 tattttttct aacatcaaga gtaggtataa gattataaaa ttgataaata agacctactt
    34921 ttctacgtct aaaaactgca agagcttctt cctttaaact tgatatttct gtatcttcaa
    34981 cataaatctt tccatatgta ggtctatcta ctcccccaag cagatgtagc aatgtagatt
    35041 tgccagaacc agatgctcct acaatggata caaaatcacc tttttgaact gataaattta
    35101 cattattaag ggctgtcact ctggtttgat ttgaaccata tatttttgtg agattttcac
    35161 attttaatat ttccatatac aatcatctcc tttatggtta aattttagca acctaaaatg
    35221 acattatagt gacatgaata caaatataaa ttactattaa aaatattgtt tagtttttgc
    35281 acattattta aaattataat ataaaacaaa aactatgcaa tatattttat ttatactttt
    35341 aatatattac atagtcttta aaaggtatta actttaaatc tataggtatt caatttaata
    35401 atcaatagca agtattttat gtactaaagg agttttgctc tatatagact caatttagta
    35461 aaattattta ataaatatta cagactatag gtaaataata tttacaaata aaattaagtt
    35521 tattccctta cactataata tttcttaatt atattaattg caatttcctt tacctttggc
    35581 cctgtaattt ctttattgga atcatctgat ttaatagcaa aataataggt gtcaccttca
    35641 cgctctagca taccaacaaa ccatgcatcc acacatttat ttttttcatc aaatcctgtt
    35701 ccagtttttc catatacatt tatgttttta tcatttacat ctattttcat aatatctctt
    35761 aaaatattaa tatgctcttt tttaaagttt gtatctccct caaatatttt tgccattgtt
    35821 tgcacttgtt cttttggaga tatttgtaat gaagattcta accaaaatcc atttaaatgt
    35881 ccctttccat tttttaaatc tccttcccat tcgctaatat cgcaattccc atactttaaa
    35941 tcatctaaaa tgttttggac agatttagca tcaactttat ctatcaattt tttgtagtac
    36001 caaacacaag actccttaaa tgcctcttct aaactaagat ttttattcca atttttattt
    36061 ggatactctg taccatcata tcccataact gattcttttg agtttattac ccctttttct
    36121 aaaccaatta aagttgaaac tattttaaaa gtagaacatg gtgaccttct tgtttcaatt
    36181 aattctttgt tatatatatt atattcttta tttttagtat tataaaaaat agctcctcca
    36241 ctaatacctt caaaacaatc actatagtca accatattaa ttttttcttt tttgttttta
    36301 ttattgtttt caattttgga tttatttaat tcagacttat ttaattcaga ttttatataa
    36361 ttcttatcag ttttttgatt tatatcgtta tgttttttcc ctacataata cattaccata
    36421 actacaccaa ccaataagat agctatccaa ataaaattct tttttctttt cataatttat
    36481 atcatctccc atatttaaat ttataaccta ctattaaaat agtagacatt atttgtaata
    36541 tactccaatc taggttctac ttataagaaa caagactaaa tgaatagctg tatctcttat
    36601 attttcttca cctagtacaa ttatgttgat taaacctatt gcgaagataa ttaagtaact
    36661 attaataaca tcctgtcctc cttttaattt gtgatataat aattgattcc acatttaaaa
    36721 cttactattg taatatttaa atattacaat agtaagtttt aaatgtcaag ttagtttggg
    36781 aaagttattt taattgtata attgttatta catttataaa atatggcatg tttaaaatta
    36841 ttttgctatt gggaggatta agataagcag tattataaaa gctataaatt ataaaattta
    36901 atatataatt tatagctttt acttttacaa atattgtttt tattgattta ttaatgaatt
    36961 ttattgacag gttatattta tataagtaaa cacttacata attaagtata taatctacat
    37021 atctataagt tgagtcaatt cacaagtata tgtcaactta agtttatgca tagctcgtgt
    37081 acaggcaata tataacaaac tgcggtcata atcactataa tatgttttat tatttactga
    37141 aggtacaata acttcatcaa actctaaacc ttttgacatt ttaatagaag ttatggatac
    37201 tccttttgta aagctagaac tttcagaaga tattaagtga acactatatt cttctcttaa
    37261 cgcatcatat acagctttag cgtcattatc tgtctttaat ataataccaa gagtcgcatt
    37321 atcactcttt ttaaattctt caatttctat ttttatctta tttatttcat cttgctcgtt
    37381 attacatttt aataaagctg gttcttcacc atgtcgttca ataggctcta atgaagatat
    37441 gtcttgaatc tttttggcga aattaataat ctcaaaagta gaacggtaac tcttgttcaa
    37501 cataactaat tccccatcat tatatagctg tttcatatca tctaatgtat gagtatgatt
    37561 aggattaacc aattgtccaa aatctccaag aatagtcttt ttacacttaa aaagtaagtt
    37621 tattacagca tattgaatag gtgtataatc ctgcatttca tcaataacaa tatgccttat
    37681 aatcttatct tcttgtatac cttcatatgt agcatgaata tatataaatg ggtatacatc
    37741 tgaccattca agtgttttct tttctaccat cacaaacatg tttgatatat tcatttgttt
    37801 aaagaaatcc ttatatagtg taagagtatt ttttattgtc aacattccat tcaaactttt
    37861 aagtatactt tttacctttg gtaaatcttc ttccataata ttatctgatt caaatttata
    37921 atgaatgtct tcagctacct tctctaatct cttcttaact ggatatctat tatatgcctc
    37981 aaatctactc tgtatccagt cacttttagc tgtaaaactt ccaaaagtgt agtcttttgg
    38041 aataaaaatc ttatttggca tttgttttat ataatcatca ataagtttta caaaatcaag
    38101 tgtagattta aaacgcactc tttcagacca tttagcatca tttatttcta atgggtcttt
    38161 ctcactttca aaattaataa ctctatctaa ttgtacctct gctatatttt caaaacttaa
    38221 ttcacataat ggctcttctc caagctcagg aaggacattg gaaatatagt ctccaaagac
    38281 tttattaggt gataggataa ttacattatt tgctgatatt ttatctttaa atcgataaag
    38341 aagaaaagca attctgtgta atgctataga tgttttccca gaaccagcta ccccttgaat
    38401 aatcagtgta tcagctttat catttctaat aatttgattt tgttcctttt gtattgttga
    38461 aatgattgac ttcatttttt catctgaagt gtgactaagt tctttttgaa gaatatcatc
    38521 ttgtatatta atggaacttt ctagtgcata ttctaatttt ccatttttaa ttttaaattg
    38581 tcgttttctt gttatttctc catccaccca tcctattgga gcatcatatc cagcttttcc
    38641 gatttcataa tcataaaaca tactggcaat tggagaacgc cagtcaagta ttataagctc
    38701 atcttcataa tcaaatgcaa atctaccaat ataatactta gattcatcat ccatatcttt
    38761 cagcctaaaa tctattctag caaagtatgg agaatctttg attttattaa tcttatctcg
    38821 aacttttacc ataaaagccc catagttatc tatttgtttt agtccttgtt cattttgaaa
    38881 catttcatgt gggtctattt caccacgatt ttttaccata tacattttag cgtccatata
    38941 atccttatca agcttgtcaa caagattttc agctttctta aaagcattgt ctagcttgtt
    39001 atttatctct attagatgtg caatctcatc tggaaaaaaa gttaataact ctgcatcata
    39061 ttcacacata ttatgtttag aattagatgc aataatatcg caatttacta cttgtttatt
    39121 ttcagacatt taaatcctcc tttgttaatt aagtacttac actgaatcat tatacttaat
    39181 tgtgttttgg agtttttaat cattcttgct atttaactta aatgttagct ttttagcttt
    39241 aaagttcctt ttttaaaaaa ctaaatcttt ctatatttat taccataagt acacttacaa
    39301 gcaaaataca ttaaaagcag aaatgctctt atatataaaa taattcaaac aaaaaatatg
    39361 tggtaaactt ttcatttaat ctacaattaa ttttgtctat tatctctttc ttctacacaa
    39421 ggaagaataa atttttgagt aggatatcca aattccacaa gcaattctgc ttctgcaaag
    39481 cccaacttct ttatcatatc tctatgtcct gtatcagctt tgtcaccctc tcgaaaggta
    39541 gtaattgaaa tatctgtatc tatcaagaaa tcttcaataa ctttcttcaa aaacacttgt
    39601 gcaatgtctg aattacgata ctgtggatgt attccaaaaa aatcaatact tctagtttct
    39661 ctattaaaca ccatatttgc aatagcgaca ttattaagtt ttaatattaa agctctttct
    39721 tctaaaatat actgttctaa ttgatatata tattcttcct cttgcaaatt tggaaatcca
    39781 tctatgacta atctcactaa attcatccat aatggtatgt cagacatact tgcaagttta
    39841 atttcttttt ccaactctag tacattcttt gaaaataggt tatctttttt caaaacaaat
    39901 cttagctgca aaggataaaa ttcttgttct ttcctatatt tatttggaga ttttttatac
    39961 atagctttaa atatagaagt gaatgcctgt tgactttcat atccagctat caatgcaatt
    40021 tcaataattg gtttctttga aaataccaat aattttgctg cttctgtcaa ctttctccgc
    40081 tttatgtaat catgcattgt tagaccaaca gaagttgtga aagttctatg caggtgatat
    40141 tttgagtaat gaacagcatt agcaactata tctaaatcca gcttttctga taaatgctcc
    40201 tctatatagt caatagcagt tatgacatta attactttgt aagacattgc agcttccctc
    40261 cttttatcca tgcaacatta tattaattat aacttagtta tatttaatga atcttaggtc
    40321 agtttacaag gaactacacg cagaccacga aacggggctg cttacaacaa ataaaagcta
    40381 aacatcaagc acagggaaag cgcgaggtgt tcagactgtt ttgttgtctg gaatttccaa
    40441 aggggctttc cccttggcaa acgactttac ttgcaaagtg tagtgtgtta tacgctctgt
    40501 tggcgttgcc gtaaaaatgc cgttgccgtc agggaaggca agggcatttg aagcggcagg
    40561 aaaacaggac tgtgattgca tagcgtgaag ccacaagcgc agggcgggtt tcagcagcat
    40621 acatgtgtat atgaaagctc ccgtccctca tcctacgctc caacttgtag ccacactcac
    40681 gaaaaagcag acggattttc ctctcaaaat tgaaataggc gggaagccat tttagggctt
    40741 tcccatcttg attgcccgtc agcaaaatca gacggtgctg tcaacggtgg cacatgaaat
    40801 gcgccgttca tcttgaccat tgactggctt ggctgacttt gctattttct atgattgtta
    40861 gttgcttgat acagatagtt gccttatcaa atccaatggt gtggtaaaag atattacagc
    40921 gcttactcta tcgccagaac cccattttac cagtccaaaa tcaacatttg cacgataggc
    40981 acattgcata tatactatcc ccaatataaa gcagttcatt gttttgacat tttgtcagtt
    41041 ccatgtattt caataatggt actgcttttg gcttatgctc tagagtgtca ttggagcata
    41101 ctacagtatt aaagtatggt gctatgtcaa agctcagaaa atcgtttcta aattcttcat
    41161 gagttttgga tgtaacaatt ccaatgccaa tatttaattt tatgagttca gtaagcattt
    41221 cctttatttc tttgaacaca agaactgtat tcttatactt ttccatattc ctatcccaca
    41281 ttgatagagc aattgttata tcttcgattt tcaaataacg taaagcgtcc tcgcctgtta
    41341 ttcctaaagc aaaagacaat tctttgatag gaattatctt tctattgatt tgttttatcg
    41401 tgtcttgtag agagtgtaaa atggcgtatt cagtatcaat caatgtgccg tctacatcaa
    41461 agacgatttc tttgtaatcc attaatttct ccttaattaa cctaatcgaa aatcactgtc
    41521 caagtgtctg tacgacatgc ttcaaagcac attttaatct gttcttctgt atttttttct
    41581 gtggcgagtt caggaagttc attttcggag aaataagaaa actccgtagt ttctatattt
    41641 tctttgaatg tacccccgat aacggtacaa agaacaaata ttttgcatac tccgtaagca
    41701 tatataggta aattgtgttt cgcacggtct tgaattgcaa taatcctgtc ggcggttata
    41761 tctaatccag cttcttcttt gacctcttta atagtatttt ccttgactga taaatttact
    41821 tcaacccaac cacccggaag cgaccacttc cctgtatttt ctttaacaag aagtattttt
    41881 ccattttcaa aaataacggc tctggtatca agttttggag tttggtatcc gctttcattg
    41941 caaaaaagat ttcttacttt ttctgttgat atgtcagttt tatatgctat catttcggcg
    42001 gaaatttctc gtattctctc atatcgctct atgtcgtata tatctttccc ataagttatt
    42061 ccggcttgag caatgctttg caattctatc gcccattcca accatttttc gttcataaaa
    42121 ttacctccag ttttccgaag aatatattat aattagttac ttagtagtaa aatatatttt
    42181 taactaatcc tgctttgtat gttgaacata ttctataatt gtaccatctg gatgtctcaa
    42241 tgtcatatta tatcctgtag gaactttttt cttatctctt actacaactg ctccattatc
    42301 caatagataa cttctccatt catcaacaga atcaaccata aaagtagatt ttgtttctat
    42361 aaatggttta agagcatcat cagaaccaga taatagtaaa acatttccta tttgcgctaa
    42421 ttctaaccca acttctttat aagaaaaacg caaagaacat ttttctttta aaagattctc
    42481 ataaaaaggt atggcttttt ctatatcttg aatataaaaa cgtgttaata tatcatatat
    42541 tttcatattt tccccctata tatctatata gtatcacttc taaattatac cactctacaa
    42601 attatataac aataaattaa gcatagcctt ttgagcatct taagtagacc ttaacaatat
    42661 attggggtta cattagaata ataaattaaa tctaaattac actaagttag ttataaattg
    42721 attatctaca gttacattag aatacataaa ttaaatcacc ttgatattat ttaggataaa
    42781 atttatgtag tagcagtaaa tgttcttcta attatcaact aacaaacgat aatctttaac
    42841 tttctatata atgggtaaca tcattttcgt aagatattca ctagctggac gattgatatc
    42901 atttaaatac tggtaatata tatcgccatg aagtttatat ccattgctat ttgcccatga
    42961 aaataagtct tctaaagtag ggtcttgtaa ttcataaggt cctaaatcaa ttgcagttat
    43021 tattttctgt gcaggaacaa tcctttgtag aatctcattt ttcccatcta tataagtggc
    43081 tacaggaaac cctacttcaa catccaattt tgctaaatcc atgttatgaa aacatacaat
    43141 cggtgctcct gaagataaaa ttcctctctc ctccagatat ttagaaattt tttcaaaact
    43201 ttgttttgaa aactctgaaa actctaccat aaagtcaatt gtttttcgta ttgccaaaaa
    43261 acagtactca gattgttcag ctattgttat attggatatt ctagtcattt tattcctcca
    43321 ttactttatt ttcatttcta atctttttat accaaattat acgaaaattc actgtgtaac
    43381 taattatttc atatgaatat aaaacataac ctccttccat ttcttatatc gaaagtatag
    43441 caaaaacaat ctcatcattc ttgtcacaca gtgctcttat aatcagaaca tacttaaaag
    43501 acttgcctaa tttttaggca agtctaaaag aaatcttttt ctataaaaaa tttatacaaa
    43561 caattaaaat atcaaacatc aaaatttaaa caagtttcag gttcatcttc tattcttgct
    43621 attttaaact tacatgcaat taatactaaa gatactattg gatttataat atttaataaa
    43681 gcgtatggac catatgttag tgcagataca cctaatgttg ctgttatata cgccccgcat
    43741 gtattccatg gtactaatgg agaagttaaa gttccactat cttctaaagc tctcgacaac
    43801 atcttaggat gtatacctct ctttttatat tccttattat acattcttcc tggtataact
    43861 atagatagat attgttcacc tgctattata ttggtaattg tacaagttac catagtacat
    43921 aatactgttc caaatacacc ctttgctaat cttagtaaag aagacgctac tacttcaagc
    43981 atacctgttt tttctaaaat acctccaaga gataaagcgc atattgttaa ggatacagtg
    44041 gacatcatat tcataatccc acctttagat aataaagcat ctacctcttg tatttgtgtt
    44101 gacgaaacat atccattttg tgctgcatct aatatcgtat tcatagattc tccttgaaaa
    44161 actactgcaa acaatactcc caatacagca cctactataa gccctggtat agcaggaact
    44221 ttaaatacaa ctaatccaat tactattgct ggagctaata ataatactgg tgataaagta
    44281 ttaaatgtag aatctaatgt agacctaatt aattctattt gttttatatc tagtgcttga
    44341 cctgaatact tcattccaat tacaccataa attactaaac aaattaataa tgatggtata
    44401 gtcgaatata gcatatattt tatatgtgta aacaaatctg ttcctgccat tgctggagct
    44461 aagttagtcg tttcagataa aggtgatagt ttatctccaa agtaagctcc agatattata
    44521 gaacctacga ttaatccaat tggcatacct aaactttgac caatgcctaa aagagctact
    44581 cctactgtac ccattgtgct ccaagatgaa cctgtcgcaa gagatactat tgcacagact
    44641 aatgttgatg ctactaaaaa aatatttggt gataaaattt ttagtcccca gtaaatcata
    44701 catggaacta ctccacttac tatccaagtt cctataagta cgcctattat aattatgatt
    44761 aagattgctt gcattgccat ctttatacta ttaaacatac ttaattctaa ctctttccat
    44821 ttaaatccaa gtctatatac agccacaagt cctgctactg ctgctgctcc tattagtggt
    44881 acatgaggtg atgaaccata cactaatact cctagactta aaaataatat caaacaagta
    44941 attggtatca ttgcatcaaa cagacttgct tttctacatt ctcgctcttt cataaaatag
    45001 tttcctccta attatttaaa cactacacta taattttttt tgaaacatat ttgctcgtac
    45061 tagatgacat gataccccca taagttaata aaaattctaa attgtcacct aatttataat
    45121 catattttgt gttacttaca tctagtatca tgtggtctga acttgcccct aatattttta
    45181 tatcagtgtc tattggaatt aaagagtcaa tatttatatc ttgtttacct atagctatga
    45241 ttgccctttt taagattccc ttatcttcat aaacaggttt atttctaaag gcatcaactc
    45301 ctatttctcc aataggaact gatggttttt ctttacattc aactacttgg catattaatt
    45361 taaatgcatc ttgatatgtt ccatttatat tttcaccgta tgccgtttct ctaccaagta
    45421 gaatggactc gcctattctc aaattagtaa taccttctgg catattatta tttatcaaca
    45481 gatgaatcga acttgaatta cctccagata ctatttctag atttattcca aatttttctt
    45541 ccattctttt tgctatactt accagtctgc ctatattttc cctagatggt ataatagctc
    45601 cataacaggt taagtttgta gctataccaa ttatttcaat attttttaat cttactatct
    45661 ctcttacatt attaaaaaag tcttcttcat aaaagtatcc ttctcgtaaa tcgcctaagt
    45721 caaacataag aactatctta tgaataatat ttttactttc acataattca tttaatttct
    45781 ttattgttcc taattctgag ttaaaactaa tatcgcaata attgataact tcttctaatt
    45841 cacttaacat tgggattcta atcaatatct taggtagatt tatatcttgt aaatttttta
    45901 agttttgtat tcttgaatct gctatatggt ctattccttc actacatatt tcttctacta
    45961 tttctttttg tgcacaaaat gatttagtaa caaaagatat cttaatattt ctttcatgac
    46021 acatctgcga aattaatttt gcattatgct ttaacttttc tatatctatt tctaacctag
    46081 gatacataat ctttcctcct caaaattcaa actttttaac aggagcttaa gagatgcttc
    46141 ttcatatttt ttagataaaa cacccataga tgccataata tagtcattat ctattaatat
    46201 ctttgttttt tcctttggaa atagtaattc attattttta ttgtatttga gcatattatc
    46261 taatatttca attctactag ggagcctagt aagtgctccc cctgtaccaa ctatatatct
    46321 tacttctgtt aaatctttcc cttctgcaat tttgactttt ccagttgttc catagatatt
    46381 tcttattttt cctgaatgtc ttagcatagc tttaacaaca gcttcttttg tcaacctctc
    46441 aacaaataat atttcttctt ttgattttgg tattggagga taattctcta ttactgcatc
    46501 aatatctata gatagttcac tttgtaagtt ttctttacct ataacttcta ctatattctt
    46561 catatttaca tatacaccta aatccccctc aacacttctc tttgcagtag gttcaggatt
    46621 aaccaaaatt ttattaatat agtcacttcc atctgtaaca gaatgtacat cagtagttgc
    46681 tccacctaca tccagagtta ataaatctcc aatattttta tataaaagtt tagaagcttc
    46741 cattacagct cctggggttg gagtaatatt ttcattaacc atttctttaa tgtatttcat
    46801 tcctggtgct gtagttatgt gttcttcaaa tacactttga atgattcttc ttgtaggttc
    46861 tatattcaat aaatctattt tagggtatac attttcagtt atataaagct tataattagt
    46921 atcttcaaat attaacctta tttcctcttg attttcaaca ttaccagcat atataactgg
    46981 tatgcctaga ttcatagaag ctatcatttc tgcattataa atagctgtat ctctttctcc
    47041 ataatcgact ccaccagcta ttaaaattat gtttgggttt atttctttta ttttatttaa
    47101 atcagttctt ttaattctac ctgatgttat ttgacgaata acagctccag cccctaaagc
    47161 tgcttcttta gctgctttta ctgtcatatc atagactaat ccatgaacag tcatttttaa
    47221 tccaccagct gcactagaag ttgcaaacat atcattatac tctatatcat ctacagataa
    47281 tttattagct aaatctttaa tagcacctga taagccattt cttacatcgc caccttcaaa
    47341 cactgttgtt ggagcttgac cttgacccaa aaatatagga ttgttagtat taatatcgtg
    47401 gaaagcgttt accactgtag tagtacttcc aatttcagct accaacacat ctatttttaa
    47461 agaaactttg ctattttcca ttatttatta ctcatttctc ttcttttttc aactaagaaa
    47521 gtggctacat gtatgccttt gctgtttctt ccaaatccag catctatgcc ttgttcaaca
    47581 gctatttcag gtgttacttg tgttcctcca cacgcaatca ttactttatc tcttatacct
    47641 ttttctacac aataatcgtg taattttttc atgtttttat agtgaatatc atcatgactt
    47701 attattgtag atgcaagtat tgcatctgca ttcagttcaa tcgctgcatc taccaatttt
    47761 tctacaggta cagaagtccc tagatagtgg cattctatgc catatttttc aatacctcca
    47821 tgttttatat ctattatttc tcttaaacca actgaatgtt catcttctcc aaccgtagct
    47881 gaaactattt tcataggttt ttcttctata tctgctctta tttcttcatc agttagtacc
    47941 ttaggttctt ctggtattac taaattgttt aaatctatat caaacggaac tcttcctttc
    48001 acttctattc tagtcccttc agattcatgc ataacttctc tacttatgac ctcaatttct
    48061 tgtaagttca tttttttgac aaattccaaa gctgcaaact ctgctgttct tttatcagta
    48121 ggaagcatca ttgttatcat tacaattcca tctgcacacc attccatttc aggcttaatt
    48181 ttagttccat ttctgtactc atatgattct tttagtctat tttctacatt atcaaaatcg
    48241 tcaagctcat caatatatat tattttgtct ggattttcaa atgtacatcc atctattaac
    48301 attgatggat tatctatagc attttcatca tattgagcta cattattgta tccaaagtga
    48361 gcagttacag gtgctaaata atcttcttct ctttcataaa cagtaccttc accaactcca
    48421 ccttttattt ttctagatat tccatcacca tttctttctg gataatttcc agaatcaaca
    48481 aaaaatcctt gttccacaga ttcaaaatat ccaccaactt cagatatttc ttccatatat
    48541 aatacagctc tttctttaag ttctcttgct ttgtctctta attcaccgac atctttaagt
    48601 tctatcatat ccataagccc atccatacca actaaagctt gctttgctgt atcacatgct
    48661 tctatattgt atatatgcca aggtacattt ctaccttcat caggtgttat agttgattgt
    48721 atgtcagctc tagttaatac tgatgttaat aagtttaata catgagtaac tgttgcttct
    48781 ctagttgatg attccatata tttagtattc atttgagctc tcatcttata atcactaaat
    48841 aactctctaa gtgcaacagc gtaaggtaag tctattttta aacatggtgc tggaggtgct
    48901 gttggtggaa ctgttgataa gcatatatta cttttatcta tacctatttt ttctgagaat
    48961 atagagttta aagcgtgttg aaccataagt tcaggcatta ccttccatgc ttctctagca
    49021 gtagcattag cattatgtgc tccatcaatt tgagctatat tggcaaaagc cattattttc
    49081 tttgcctcac aagcatctac aaaagacctt accatgttta tattcctata cagaacatta
    49141 tattgtgggt cttgatgtgc tccattgact ccttcctcag caaacattac tgctacttca
    49201 ggaccagcaa caccacttac atatgaatgg taattaatag gtctaccaac ttcttcttct
    49261 ataaaatcaa gagccttcct ttgagctctt acttgttttc ttgttattgg aactccacct
    49321 ataccttgtg gagttccttc tataagccca tcaaaatgtg attgtccagc agttctgata
    49381 accattagat ggtcagctcc atgatgagct gccattctca ttcttcttat atcatcctca
    49441 aatctaccag aagctatttc agtagtaata actggacttg gttgagggtc tatattattg
    49501 aaatacttag atgatggtag ccctacactc ttctttaaag gttttgtaca gtctttatat
    49561 ttaaaaggtc ccatttcaag attttccaag tgttctctcc aaacccaacc tcttcgtttt
    49621 ggtttatatt tatccaaatc ttttaatata tagtctatat ccaatttttt attttccttt
    49681 aacatgattc taccccttct ctaaataaac atgtaacttc atcccaatat tcacccttaa
    49741 ctaataacaa acctgcttct ctaaccgtta tatttttaga tttagccaat ttataaacta
    49801 catgccctgc tcctttacct ataagacctc tttccataac cccttctaaa ataggtttta
    49861 cttcaagaga agaaaatccc attctcaaca agacagacct ttctattgat ggtgttgtat
    49921 tctttttacc aagttctatc attggttcta ctatctgggt agctaaactc caaaaccttt
    49981 cttttaactc atcctcactc agttcttgaa gatgttttct tctaacttca aaatcatcct
    50041 ctcttttttt catgaacatt cctccattcg tattgattta atcgaatttt ctgaattttt
    50101 attttatatt aaattaaaaa acaataatta ctataaatta tttaatacat caacaacaaa
    50161 atctcttgaa ctttttactt cttccattaa aaattctata tctcgattac ttagcttatc
    50221 aatattatca atgtgattat tagatataca attttttata aatgactttc ttattttatt
    50281 catatcaata tcaacacatt tcaataattc tggtctttct ggtaatatta agtttactcc
    50341 tgcaatttct tctcttggat ttccaaattt tatatctatt ccattttctc ttgcaaaggt
    50401 aagttgtgga catatatgtt tacctgcacc cgtatattct gtttcttgta ccactatagc
    50461 tttatcctca tctagctctt gagctaaaga gaatgctgct gctaaagatg tatttcctgc
    50521 tggacctctt tctatacctt ctagctgtgc caataattca gttgtataaa aaacttctcc
    50581 ttgttttact aatacatatc tatccatata tctaagtggt ctagctgcag acctaggtac
    50641 atctgaccta tcaggccatg tacagtatgg tatcccaaaa cctgtatgtc ctgttgtaaa
    50701 tgatttttta ttaaattgat tatcactagc catgtgtaat ccttttaaat ctacacttgc
    50761 tcctactact ttagtattaa tagaaccagc ttttatcaat cctcttgcag ttccagtaag
    50821 attaccacca cctgcatttg tacaaacaac tatatcaggg tcttttttat acttttctct
    50881 aaattggata gctaactcat aacctaaagt ttctacacct gcaattccaa atggtgaata
    50941 taatgatgcg ttaaaatagc ctgtttcttc taataaaact aagaacgtat aaaataactc
    51001 tggtccaaca gttaactgaa caacttctgc tccatatgcc tcacattttc gcgctttttc
    51061 tatgatttca ggttgaccta caccattaga atcataacat tcttgaacta ttatacattt
    51121 taatccctgc attgccgctt gtgatgctac agctgcacca taattaccac tagtagctgc
    51181 tattacacct ttatatccca tttgtttggc atgatatact gcagtagctg ctcttcttgc
    51241 tttaaaacta ccagatgcat tcattgcttc atcttttaca aatattctag ctcctttacc
    51301 ttctttagca cattttctag ctaatttagt caaattttta agctctatta aaggagtatt
    51361 tccaacagca tactgtgatt gaattgcttc aatatcttgt aatgtatatc ctgtttcact
    51421 catcattttc tcataatcaa accctattcc ctcttgttca aaagaagaat aatccaatcc
    51481 gattgcattt ttcattattt cgttatttct tcccataaca gcttgataac tcatatcttt
    51541 cattgatgtt gaattattca ttatatacac ctccaaataa tatttcttta gcttggattc
    51601 ctatttggag taactctggt atacatttac cataatcatg agtataatat ggatttactt
    51661 taagtaaatt accttttaca agtctacctg taattgtttt aacttctact aagtcgccta
    51721 tagaagcatc actttgtata aaacctttaa cccacatttc taaggatact ttcttagtat
    51781 cctctggaac ttgtggagct ctttcttctg gagtcaatac tatattgtgt ataataaccc
    51841 aatcattaat tttagcatcc attttttcat ccccttatta attgactatt gccttactaa
    51901 ttaatttact gttattttaa attaaacatt attttaccaa ttagctaact gttatcttac
    51961 taattagcta gttgctatct tactaattag ttagctgtta tcttactaat tagcctttga
    52021 ttcttcttcc aattcaactt ctatctgatt tcttatatct cccattattg ctctaggtac
    52081 tggtatatcc aacatagttt taagacctgg tctagcattt attattaatg gaatagagtt
    52141 tactatcatt gcataagtac ctactcctcc aggtatttca ggatttattt gtaaatcaat
    52201 gtttggtata ccttttattg atacatagtc tcctgtttta ataccttctg cttctggtat
    52261 tatctgttgt ggatgctcca tttcaattaa aacttctcca tttacatatc catatccaca
    52321 ttgtctacaa ccagcaacat ttccagccaa tgcctctccg tacttagatt ttctatctac
    52381 tgtagtcatt attggctctt ttgtttgttc tatcttatct aatttccaac ctaatccatc
    52441 agctatcata tttattgatt ctacaaaacc tacatgacct gctatagtct tatcttctac
    52501 accttttata aattcttccc ttgttactcc aacaccttgt tccaccataa cagactttcc
    52561 aaatggagat aaatcattta ctctcttagc ttttatacta gtaacttctt cacaagtacc
    52621 tgaaagtgcc aatactagta aatctaatac aaatcctgga tttattcctg ttccaagtat
    52681 acttactcca ttttcctttg caacttcatc cattttttta gctaaatctg catcatcagc
    52741 ttgtggatat gccatttgtt ctgctgttga tataacattt atttttctat ttaataagaa
    52801 aattatttta tcaaaagcct ttttagtaaa tgaatcagtt gctaacaaaa caacatctac
    52861 acttttttct ctaaaaactt cttcataatt tttattgata ataacttctg gtctttctcc
    52921 tctttcaatt cctaaaacat catacatact tttccctgaa gtacttctac tacaaacaga
    52981 tactatttct ataccttctt tctttagaat catattagcc atacctattc ccatagctcc
    53041 aaatccccat attcctactc ttacttttct catatataca ccctcctaaa aatttatata
    53101 ttctcaataa ttagttaaag cataaatcgt gccaacttta aaattaaagt aaatatttat
    53161 tggaacgttg aaactataat tattttatta tgtattttca taaataaaaa ataatatttc
    53221 ttatgagaaa taaaaaaaag agcaaaatat tttgctcttt tataataatt ttgctcctct
    53281 attttgcttt tttattttac tttgattttg tttttttatc ttgcttattt ataatatttt
    53341 gatattatat ttttttattt tatactgtaa attttgccta ttcataccta aaattgatgc
    53401 agctttagtt atattgtaag atgccttttc taatgattca tatatatact tttcttctat
    53461 ctcactgata atcttactaa gtgttttgtc ctccaaatcg tttaaagaat aattgttact
    53521 ctctttattc tctttaagat tgtaatagtc gtttagatta atcatacttg tttctatttg
    53581 tacctcatct tccatcatac tcatagtaca ataaattatg ttttctagct ctcttatgtt
    53641 accttgccaa tcgtaatttt ttaaaatttt aatagcttca tctgaaattc ctaccacttt
    53701 tttatttaac tttttattat actttgaaat aaattttttg cacaatagag gtatgtcctc
    53761 ttttctatct ctaagaggag gaatttttat atgaattatg ttaagcctat aatataaatc
    53821 ttttcgcatt ttatgctcgt ttaaaattac ctttggactt tcatttgtcg ttgcaataat
    53881 tcttacatct ataggtatat ccttagttcc tccaaccctt cttacataac cttcttgtaa
    53941 aacccttaat agtttagcct gtaacataat aggcatggaa tttatctcat ccaataacaa
    54001 tgtccctttg ttagcttgtt caaataagcc tggcctatct attgctcctg taaatcctcc
    54061 cttgctagtt ccaaaaagaa taccttcgaa tagtgattcc ggcaaagctg cacaattttg
    54121 tgctataaat ggatagtttt tcctattact tccatagtga atggactggc taaataactc
    54181 tttacccgtt ccagtttcac cgtatataaa tactgaagca tcagacttgc aagctttctt
    54241 agatttagct attgcttctt taatcaaatt actttcccct aaaatatcat caaattcata
    54301 accctttttt tgtctactac taactttatt gactaaattt tttttataat ttctgtttag
    54361 taaattttct atcgttgtca tattctttga tatttcaagt gcccctacaa actcgccttt
    54421 aatatcaatt ggtattgtag tattaattgc tgttatctct tttccatttt tatccagata
    54481 tttttgaata ttgtctttga taacttccct tttttccaaa acttctaata gtgtactcct
    54541 gtttattttc attttgttga ctatatcaaa aaatgaattg gttaaaatat catgtctgtt
    54601 cattttttcc attttttgta cagaattatt gtagattata gttttcccgt ctttattaac
    54661 aaaatgtacc ccttcatcaa tattttccaa tatttcattc attattttaa aaaatatctc
    54721 ttggttcaac tatatcaccc cagtacctaa atatataaaa acccaaaaaa ttaataaaat
    54781 gttgctattg tatttatctt atcatatatt gatgatattt tttatgtaca ttatattaat
    54841 atatttttaa gtatatttaa aattttattt atatatcttt cattatggtt atatacaata
    54901 tttgaattgt cattaaatat accaatagtt ttatatatta ttgattttat taaaaaaaga
    54961 gatatacaaa ctaataagtt gtaatctctt ttaaactcta aattagaatt actctaatat
    55021 ataacttaca atataatcca atgtcctgtt tatagtaaaa accacattta aattttagat
    55081 tggatgaaaa ttattaagat tatttataaa ctcaaattgt tactctcctt tttcttatta
    55141 tcttttgaat gtattcttta gttaaaaagt tttactttct catatattat aaaggaagat
    55201 aattttttac aaataatcca cttaatagca tccttacttt aaacctaaag ttcctctatt
    55261 ccaatttctt ttaagtattc atacacacca ttataaaaat ttggctgcat tgtaatatca
    55321 ctctcatcac ctattgggac aaatataata aagccttgcc ttgcccttgt aagaagaact
    55381 ctatatgcat tttttaagta tagtatatta tcttctttat tgatgttctg ccatttagtt
    55441 ccattgaagt tatagtattc aaaatggtta ttcttaaatc ttaagttccc atcccaacag
    55501 acaattgtcc agtctagctc taaaccttgg atatcaaact ctgttgcagt ttcttctaaa
    55561 aaatatgaag ctcgtacatc atccttacca ttaagaaacc agtttgtagc atcaatttta
    55621 ttttgtaccc acactccata ctttcgaagc cgtttagctc cagaacttgc agtcattcca
    55681 taacgctgtg aaccttttga tttatctctc acccactttt tagctaattc caaatcccta
    55741 gtaacacata tagggtaatc ttttttaaat tgattatata attcctttgc agcaacttta
    55801 tctacatcca aaacagcttt aacaaaggtt gatacatttt cacttctaaa agaacgtaac
    55861 gatacagata agtgcaaatc atcaattatt ctataattaa caccttctgt taactcatca
    55921 aaagaattac ctttagaata ttcttcatca ataattttat ttgatatgta aacatcccaa
    55981 tcagaataat tatttcttag tgattcaaac caacctgata ttccatctga ctcaccttta
    56041 tttatctctt gacctccacc aatcaaacaa acaatagtcg cccatcctat atgacgattt
    56101 aaaatactaa taagaaattc aggctctgac atattaaagt ctaatacgcc tttttttctt
    56161 ttcataaagt tagtcaaatt aggttcatcc cacgcacgtt gtgcttcatc aaaaattgtg
    56221 actctttcaa taggtggtgt atcaacagat atagcttcat ctctaaaatg atgaattatc
    56281 tgaataaatt ctttcgcttt tcgaatcgct tcagattttc gtattccatt tctggttaca
    56341 tcatcacgag ctagtgcttc ttgtaaaaca tcaactaatg gaccatttcc agaaaggaag
    56401 actgcatgtt cattttcatc tactttttgt cgctcaatgg caatattaag gccagcaagt
    56461 gttttacctg ctcctggaac tcctgtgata aaacatattg attttctgtt atgagtctta
    56521 ctatagtcta taattttatt tatagcttta gttgtttgat ttaaattttt agcacttgca
    56581 tcatttcttg aaatatcttc aacattatgg cccatatata aagcttgtgc agcttcaata
    56641 attgttggag ttggcatgta taacgagttt atccaagtgt ctgaattaaa tgaacttcta
    56701 ttatatgtag tacaaatctt ctttatgtat tttcctatat taaactcatt acaacaataa
    56761 gtttctaaaa tattttcctt catcattctt attctttggt ctttttgagg ggcttttgta
    56821 caaataagta ttggtactaa aagtttatca tgactttctt tgtgaaaaca attaaggtca
    56881 agggcatagt ctgtaacttg ttcaattgca tgcctaggat aagtgtcttc atcaacttta
    56941 aattcaagga gaaaaacaat gcccttgtaa attaacacat tgtcaattct actgcctatt
    57001 cgtggtattg tatactcaaa taataagtgt ccatctttga aagttgagag ctctcttttt
    57061 aatattccaa tttccttttt ccatgtattc ttttgtaagt catcagccgc aaattgatca
    57121 ttacacgtta tctcaccaaa tatagtaaaa atatctttga ctataaattc atttacacta
    57181 cttgaataat atgctctttt catacatctt ccccctttat atctaatatt cattttatag
    57241 cctacatcta tactacaatc taaaacttga ctcctatact ttataaatac actacataga
    57301 tatgtttatg tatggtactt tgataataat ttttctttgc taagtacatt ataaactatt
    57361 taattaatat gttttttcca tatatgctta ttatattata aaatggatag cgcatcattt
    57421 aaatcattga ttaaatcttc actattttca agacctaaac ttattctaat tgtgtatggt
    57481 gacacattta atgccttggc ttgttctaaa gtcatttcat ttaatatagc tatatttgga
    57541 gcaaatacta aactttcatg gcctccccaa ctcactccta ttttaaataa atctaattta
    57601 tttacaaatt ttttaacatc atttacatcc tttgcgtcta tttcaaaact taataacgca
    57661 gtataattaa gcaactgttt ctttgctagt tctttttgat taaaatattt agataatgga
    57721 tgatatacct tagtaactgc tgaatgatta tctaaaaatt caactacttc cttagcattt
    57781 ttggtatgta ctgataatct agcgtgtaaa gttctcaaac ctcttataac taaaaatgct
    57841 tcaaatggtg ctaattttgc accatataaa gctaattcac tccctcttat ttcttctata
    57901 tcttttttac ttccaataat acatccacct accacatctg aatgtccatt taaatattta
    57961 gataaagaat gaacttctaa atcaattccc atctcaatac atctttgata taatggtgta
    58021 gcccaagtat tatctattac tgtttttata ttgtgtgttt ttgctagtgc tacaattgcc
    58081 tttatatctt gcattttaaa tactgatgtt gatggacact ctaggtatat taaagttgta
    58141 ttttgtttta tagcattttc aaaatcttct attctatcac cttcaactat tgtattttct
    58201 atatttcctt tctccttcaa ttcctttgtt ataaagttca ttgtaggatt gtataaatta
    58261 tttgaagcta ttatatggtc accatttttt acaaaatgaa gtatagcact tgatatagca
    58321 cccattcctg aaccaaaggt tatacttgct tcagcattag ctaatgcaga taactttgct
    58381 tctaaaatat cattagtagg atttttagtt cttgaataaa gatatccatc ttttgaacct
    58441 tcaaaatatg cttctatatc ttcatatgta cttcttgcga atattgatga ttgatatata
    58501 ggtgggttta cagctccata atcgccatcc aaattttctc ctacatgatt cattaatgtc
    58561 tctatcttat atttattttt atccatgttc taaatctcct tatgaaatat ttttatatat
    58621 gaaaaataca tttaacatag cttatttttt ataagctatg ttaggtaata aagttaaaat
    58681 attcattatg atactttatt agattgtttt ttatcctttg aatttttata tgtacctatc
    58741 cctgtaactg ctaagattac tgctataatt ggagttcccc agttcactat agaccaaagt
    58801 gcgtattctc caacattaac tcctagtgtc tgagtgaaaa atattgctgc tggtgtccaa
    58861 ggaaataaaa cttctaacaa tgtacctgta tcttctgtag ttcttgatag taccctacga
    58921 tctatattat tctcatcgta tttatctcca aatatacctg ctgttacaaa actacatgct
    58981 ataccatttg cagtcattgc tatcattgct attcctgtta ataatgaaga acatattata
    59041 gccgttctag acttaaccca cccaaatatc acatttaccg ttgctggcat agcatcaata
    59101 cttccaagta ctccaacaac aaataatata gatgttgata ttggcaataa tttacctaat
    59161 tcccagaagc cacctttttg gaaaaaacct aatatataag cttgtccttc tataggtttt
    59221 gcatattcat gccaagttac catatctagt gagaatccac tgttaagtcc tataagaaca
    59281 tctgccaaag aaaaaccttg aaagattact gcaaatgcaa gtgataaaaa tgctgctatt
    59341 gtcattactg gtattgcagg ttttttcatt gctgaaccta ctaatactat taaaagaggt
    59401 ataaataaaa ttatattgaa attgaacatt cctgataaat ctgccaataa tctagttatt
    59461 tctggactat ttaaatttgt atttgttgct gggaatataa acccacaagc aatatatata
    59521 actaaagcta ttatagttgc tggacctgtt gtccataaca tagatgcaac atggtcatat
    59581 aaattaactt ttgacgctat tgcagctata tttgttgtat ctgatagggg tgacatttta
    59641 tcaccaaagt aagctccacc tactatagca cctgctataa tagcattgtt tgctcctatt
    59701 gcattaccta cccccatcat tacaactcct atagttgctg ctgatcccca ggaagttcct
    59761 gtaaatgaag aaaacaatgc tgacaatatt aatgctgtag catatacaaa tcttggattt
    59821 atcaatttaa ctccataata tactaacata ggcattaatc cactcataat aaatcctgca
    59881 ataagtggac ctattactaa taatattatt aatcctggta aagctccttt tacaccatct
    59941 aatccacttt caaatacttc ttcccacgtt ttatttgttg taaccactat aaatagcgat
    60001 attattgatg ctgaaataaa cattattgac tctattggca aactatattc cggcttattg
    60061 ttaatcattg gaagtaatag cccacaaaat aaaactgcca taaacaaaac tatagatata
    60121 gcctgctttt gaattgtaac ttttctcttc atttattatt tcctcccact tttatttact
    60181 cattaattca atttttaata acgttttccc ttatctaaca ataaaattta ctatcttata
    60241 ttta
//
LOCUS       DAEOTL010000013        58899 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEOTL010000013 DAEOTL010000000
VERSION     DAEOTL010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58899
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.013"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            155..1231
                     /locus_tag="KRH82_001126"
     CDS             155..1231
                     /locus_tag="KRH82_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8654416.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1348..2190)
                     /locus_tag="KRH82_001127"
     CDS             complement(1348..2190)
                     /locus_tag="KRH82_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBG8654417.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2374..2946
                     /locus_tag="KRH82_001128"
     CDS             2374..2946
                     /locus_tag="KRH82_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654418.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSKNEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3109..3381)
                     /locus_tag="KRH82_001129"
     CDS             complement(3109..3381)
                     /locus_tag="KRH82_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654419.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3508..4380)
                     /locus_tag="KRH82_001130"
     CDS             complement(3508..4380)
                     /locus_tag="KRH82_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8654420.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4676..7783)
                     /locus_tag="KRH82_001131"
     CDS             complement(4676..7783)
                     /locus_tag="KRH82_001131"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBG8654421.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7876..8108)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8283..8810)
                     /locus_tag="KRH82_001132"
     CDS             complement(8283..8810)
                     /locus_tag="KRH82_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBG8654422.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8845..9630)
                     /locus_tag="KRH82_001133"
     CDS             complement(8845..9630)
                     /locus_tag="KRH82_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBG8654423.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYERAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9640..9897)
                     /locus_tag="KRH82_001134"
     CDS             complement(9640..9897)
                     /locus_tag="KRH82_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBG8654424.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9916..10374)
                     /locus_tag="KRH82_001135"
     CDS             complement(9916..10374)
                     /locus_tag="KRH82_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBG8654425.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     TKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10414..11118)
                     /locus_tag="KRH82_001136"
     CDS             complement(10414..11118)
                     /locus_tag="KRH82_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBG8654426.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11128..11763)
                     /locus_tag="KRH82_001137"
     CDS             complement(11128..11763)
                     /locus_tag="KRH82_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654427.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVNTLVLKNEKVDAK
                     IHVKGSIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12144..13184
                     /locus_tag="KRH82_001138"
     CDS             12144..13184
                     /locus_tag="KRH82_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8654428.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13647..15002)
                     /locus_tag="KRH82_001139"
     CDS             complement(13647..15002)
                     /locus_tag="KRH82_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBG8654429.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDSVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15028..15297)
                     /locus_tag="KRH82_001140"
     CDS             complement(15028..15297)
                     /locus_tag="KRH82_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBG8654430.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(15587..17557)
                     /locus_tag="KRH82_001141"
     CDS             complement(15587..17557)
                     /locus_tag="KRH82_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654431.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENNNNENDNSD
                     EKQPNTPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLS
                     SKSVFGTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIF
                     LFCILTPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(17740..19215)
                     /gene="spoIVA"
                     /locus_tag="KRH82_001142"
     CDS             complement(17740..19215)
                     /gene="spoIVA"
                     /locus_tag="KRH82_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBG8654432.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(19387..20682)
                     /locus_tag="KRH82_001143"
     CDS             complement(19387..20682)
                     /locus_tag="KRH82_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8654433.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSAINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPVASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENTTKVS"
     gene            complement(20866..22275)
                     /locus_tag="KRH82_001144"
     CDS             complement(20866..22275)
                     /locus_tag="KRH82_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8654434.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(22327..23466)
                     /locus_tag="KRH82_001145"
     CDS             complement(22327..23466)
                     /locus_tag="KRH82_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8654435.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            23785..24435
                     /locus_tag="KRH82_001146"
     CDS             23785..24435
                     /locus_tag="KRH82_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654436.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(24592..25611)
                     /locus_tag="KRH82_001147"
     CDS             complement(24592..25611)
                     /locus_tag="KRH82_001147"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBG8654437.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVSEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(25642..26256)
                     /gene="plsY"
                     /locus_tag="KRH82_001148"
     CDS             complement(25642..26256)
                     /gene="plsY"
                     /locus_tag="KRH82_001148"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBG8654438.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(26291..27610)
                     /gene="der"
                     /locus_tag="KRH82_001149"
     CDS             complement(26291..27610)
                     /gene="der"
                     /locus_tag="KRH82_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBG8654439.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(27644..28972)
                     /locus_tag="KRH82_001150"
     CDS             complement(27644..28972)
                     /locus_tag="KRH82_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBG8654440.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(29210..29410)
                     /locus_tag="KRH82_001151"
     CDS             complement(29210..29410)
                     /locus_tag="KRH82_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654441.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(29412..30344)
                     /locus_tag="KRH82_001152"
     CDS             complement(29412..30344)
                     /locus_tag="KRH82_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBG8654442.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(30389..31321)
                     /locus_tag="KRH82_001153"
     CDS             complement(30389..31321)
                     /locus_tag="KRH82_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBG8654443.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(31376..32665)
                     /locus_tag="KRH82_001154"
     CDS             complement(31376..32665)
                     /locus_tag="KRH82_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8654444.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(32694..33386)
                     /locus_tag="KRH82_001155"
     CDS             complement(32694..33386)
                     /locus_tag="KRH82_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654445.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(33401..34162)
                     /gene="pgeF"
                     /locus_tag="KRH82_001156"
     CDS             complement(33401..34162)
                     /gene="pgeF"
                     /locus_tag="KRH82_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBG8654446.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(34159..34620)
                     /gene="nrdR"
                     /locus_tag="KRH82_001157"
     CDS             complement(34159..34620)
                     /gene="nrdR"
                     /locus_tag="KRH82_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBG8654447.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(34642..34905)
                     /locus_tag="KRH82_001158"
     CDS             complement(34642..34905)
                     /locus_tag="KRH82_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBG8654448.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(35009..35782)
                     /gene="sigG"
                     /locus_tag="KRH82_001159"
     CDS             complement(35009..35782)
                     /gene="sigG"
                     /locus_tag="KRH82_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBG8654449.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(35874..36596)
                     /gene="sigE"
                     /locus_tag="KRH82_001160"
     CDS             complement(35874..36596)
                     /gene="sigE"
                     /locus_tag="KRH82_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBG8654450.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(36621..37493)
                     /locus_tag="KRH82_001161"
     CDS             complement(36621..37493)
                     /locus_tag="KRH82_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBG8654451.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(37783..39057)
                     /locus_tag="KRH82_001162"
     CDS             complement(37783..39057)
                     /locus_tag="KRH82_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBG8654452.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(39341..40498)
                     /gene="ftsZ"
                     /locus_tag="KRH82_001163"
     CDS             complement(39341..40498)
                     /gene="ftsZ"
                     /locus_tag="KRH82_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBG8654453.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(40688..41041)
                     /locus_tag="KRH82_001164"
     CDS             complement(40688..41041)
                     /locus_tag="KRH82_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBG8654454.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(41140..41814)
                     /locus_tag="KRH82_001165"
     CDS             complement(41140..41814)
                     /locus_tag="KRH82_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBG8654455.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTITGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(41819..42517)
                     /locus_tag="KRH82_001166"
     CDS             complement(41819..42517)
                     /locus_tag="KRH82_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBG8654456.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKDIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(42540..43280)
                     /locus_tag="KRH82_001167"
     CDS             complement(42540..43280)
                     /locus_tag="KRH82_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBG8654457.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(43550..44776)
                     /gene="murG"
                     /locus_tag="KRH82_001168"
     CDS             complement(43550..44776)
                     /gene="murG"
                     /locus_tag="KRH82_001168"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBG8654458.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(44794..45924)
                     /gene="spoVE"
                     /locus_tag="KRH82_001169"
     CDS             complement(44794..45924)
                     /gene="spoVE"
                     /locus_tag="KRH82_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBG8654459.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(45976..47331)
                     /locus_tag="KRH82_001170"
     CDS             complement(45976..47331)
                     /locus_tag="KRH82_001170"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBG8654460.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(47350..48318)
                     /locus_tag="KRH82_001171"
     CDS             complement(47350..48318)
                     /locus_tag="KRH82_001171"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBG8654461.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(48359..49732)
                     /locus_tag="KRH82_001172"
     CDS             complement(48359..49732)
                     /locus_tag="KRH82_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBG8654462.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHAYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(49899..51878)
                     /locus_tag="KRH82_001173"
     CDS             complement(49899..51878)
                     /locus_tag="KRH82_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBG8654463.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(51890..52237)
                     /locus_tag="KRH82_001174"
     CDS             complement(51890..52237)
                     /locus_tag="KRH82_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654464.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(52723..53658)
                     /gene="rsmH"
                     /locus_tag="KRH82_001175"
     CDS             complement(52723..53658)
                     /gene="rsmH"
                     /locus_tag="KRH82_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBG8654465.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(53688..54434)
                     /locus_tag="KRH82_001176"
     CDS             complement(53688..54434)
                     /locus_tag="KRH82_001176"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBG8654466.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(54828..56114)
                     /locus_tag="KRH82_001177"
     CDS             complement(54828..56114)
                     /locus_tag="KRH82_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBG8654467.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDRLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(56129..57394)
                     /locus_tag="KRH82_001178"
     CDS             complement(56129..57394)
                     /locus_tag="KRH82_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBG8654468.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            57710..58807
                     /gene="ychF"
                     /locus_tag="KRH82_001179"
     CDS             57710..58807
                     /gene="ychF"
                     /locus_tag="KRH82_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBG8654469.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        18464 a        10668 c         6339 g        23428 t
ORIGIN      
        1 tttacttccg tatttaatgc aaaagtagag attaaactta atataaaaaa tatataacaa
       61 atttttttta tatttctaga agaaaagtat actctttttt gtttaataat gctaaaattg
      121 atttgtattg aattttgatt aggaggaaat tattatgaaa gctcaaagat taaatgctgt
      181 acttgaacaa atgaaaaaag atgatatttc tcaaatgtta gtaagtgacc ctacttctat
      241 attttatctt acaggagtac taatccatcc aggcgaaaga ctattagcat tatacttaaa
      301 tttaaatggc aataataaat tatttataaa tgaattattc ccagtttcag aagatttagg
      361 tgttgaaatg gtttggttta atgatactca aaatccagta gaaataataa ctgaacatat
      421 agacaaaaat gctactatgg gtgttgataa aaactggcca gctagattct tattaaactt
      481 aatagaatta ggtggaggaa gtaagtttgt aaattcatct tatataatag atactttaag
      541 aatgtgtaaa gatgaagaag aaaaagagtt aatgagaata gcttcaaaat taaatgacaa
      601 ggctatggaa caacttaaag ctactgtttc tggtgaactt acagaaaaac aacttgttgg
      661 taaattatct aaaatatatg aagacctagg tactgatgga ttttcatttg accctattat
      721 aggttttgga cctaatggag ctaatccaca tggtgaacct ggaaatgcac ttgtgaaacc
      781 aggagatgca ataatcttag atataggttg tataaaagat aactattgtg ctgatatgac
      841 aagaactgta ttctataaag aaatacctga aaaaggtaga gaaatatttg aaatagttct
      901 tgaagctaat aagagagctg aagctattgt aaaaccaggt gttagattct gtgatataga
      961 tgctgctgct cgtgactaca taactgaaaa gggatatgga cagtacttca ctcatagaac
     1021 tggtcactct ataggacttg aagttcatga taaaggagat gtatcttcta taaatacaga
     1081 tactgtacaa ccaggaatga tattctctat agagccaggt atatatttac caggtgagtt
     1141 cggagttaga atagaagatt tagtacttgt tactgaagat ggttgtgaga tattaaacaa
     1201 acatgacaaa gaaatatgtg tagttggtta attctaaaat caatttgata aaattaaaaa
     1261 gccatataaa aatgttttaa acatttttat atggctttaa tttctcaatc tatgatttat
     1321 ttcaatccat tatttatatt gcagtattta tattgcagtt attaagattg caccctttga
     1381 agtatatgtc cccatcactg aaccaatttc acagattaca acatctttgt attttacatc
     1441 cttttccata acctccctca ccttttgagc tttttctggg caattagcat gtcctataaa
     1501 taaaaccttt tcttctttat ctttaatttt tgactctact aaagtaatca gctttttcaa
     1561 actgtttcct tcacctcttg ccttatctat aggagttaca acgccatctg caacttgtat
     1621 tatcgcctta aaattcaagg tatttataat ttttcctgct attggattta ttctaccacc
     1681 cttaatagca ttttctaaag tttcaagtgt tccaaaaaat ggaggattat ctttatattt
     1741 atttattatt gaaacaatct cttcaatttc ttttccttct tttattaata ttgctgcttt
     1801 taacactaat tgtcctattc caattgaccc actaagtgaa tctataacct caactttctt
     1861 gttatttcct tccttttcaa acatatcttt tgctaaaagt gcactattat aagtcccaga
     1921 taatcctgaa cttatattaa tcactaatac actttcttcc tgacaatggt atgcttctaa
     1981 aaatttatca ggagaaggac atgatgtttt tggtagtact ttactctcac tcatttttct
     2041 atagaaagtt tcattatcta tttcctttcc agatatataa ctttcttctc caaaagatac
     2101 atttaaacca acaacttcta tgttgtattt ttctattata tcatcaggta agtcacatgc
     2161 actgtccact atcaatttta ttttatccat attaacctca ctataagata ttattttatt
     2221 tattcagtcg gtcgtacgac cgatttaatt attattttat atattgaatg aaaaaaagtc
     2281 aatagatata gattctcgct ttattgacaa taaatatcca taagcttata atgttattaa
     2341 tttgttataa atatacatgg aaaggtaggt tttatgaaaa caaataatat gaaacaggct
     2401 attttatcat ctgcaaccaa tttaatagcc aaaaatggag ttcaaaatac tagccttgct
     2461 gatattgcaa aagatgtaaa tataagtaaa ggtactttgt attatcacta cgcatctaaa
     2521 gatgatatta tatatgatat tgcggatact catttagaag ttataactag tgctatacta
     2581 aactgtgtaa aaaatgtcaa atcaaaaaat tctcaaatag aaatggttaa cttaatctta
     2641 gagaaaatat ctactataga aagtcgtggt agggtacata tgtatcttat ttgtgaggca
     2701 attacttcaa ataatgattt aaaggaaaga ataagattaa aatatattga atggagaact
     2761 actcttaaat ctgaaattgt tgaatcacta gaaaaatata atagtagcaa aaatgaacag
     2821 gatgctgaat cattttcttt tttgctcatg tcaatagttg atggtttagt tgtccaaagt
     2881 ttattaaaaa cagaaaaaat accttatgaa aatatagctt cttttttagt taatcattgg
     2941 atttaaactt aatacttaga taattaataa aagtgaacta tttaagttat ctactttaac
     3001 agttcacttt cttatttatt ctcaataatt tttacttaaa acattcaatt tttatttaaa
     3061 ccttcatgga atcacaaaat aaaaatctct tataaattta aaatgttttt atttatgttc
     3121 atgtgtatgc ccatctgaat gttcatgacc atgtgtatgt gtatgttcgt ggctatgctc
     3181 atgagtacct gaaaaaccat catcatgatt atggtcgtga cctacaccat ttacatgctc
     3241 atgttcatgc ccatgactgt gagaatgttg atgtgaatgt tcatggttat ctcctccaca
     3301 gcatccttct cctccagtcc cacaacaccc acttgtatgt ggattatgat gatttcttac
     3361 tacaaatctt tctcttaaca taattcttat acctcctagt atattattga gtacttcatg
     3421 taccccatta actacagtat acatctaact aggtataatc tcaatacata tggcattttt
     3481 taacatatat aattaacata tataatctta aagaaattta tccttaaaac ctccaccttt
     3541 tacttcttca acgttattga cagaaataaa agcttcacta tccatatcat aaattaaatc
     3601 tttaaattta cctatttcat ttgcagatat tatgcaataa atcatctttt tcttattttg
     3661 tgtatatgca ccttctgcct ccaaaaaagt gactcctcta cccattttat tcattatcac
     3721 tttggatatt tcatcatatt tatttgatat taaaagtata gatttttttc tatcaaagca
     3781 atcttttcct atatccatag taaaagaaat tatatacatt gtaattaaag tgtacatcac
     3841 caatttagct ccaaataaaa aagctcctgc acatactaca aaaaaattaa taaataaaaa
     3901 tgtatttttc ataggtatat catactttct tttcattatg gctgctatta tatcaagtcc
     3961 tccagcagta gctcttgctt taaaagttaa ccccatacct ataccagtta atgcaccacc
     4021 ataaatacac tgtagcatag tatcatctat tgggaaatat ttagcaatat cttgtgttag
     4081 ccccagtgct agagaaaata gtaacatatt gacaaaactt attagcaaaa atttattatc
     4141 aaaatacttt ctagctataa taaatattgg tatgttcatc aagaaacttg atattccctg
     4201 atttatacca aataatttgt ataatataac acaaattcca gctactcctc cacttaataa
     4261 cttggctggt gctagatata aatttattcc taaggttgat agaatcatac ccaatataat
     4321 aagacaatat tgtaaaaata tgttattatc aatacttagc tttttacttt caccatacat
     4381 caaaacgcac ccctttgcat aataaataaa ccaccctgca gaacacacga taaatttaca
     4441 aataaattta tcagaagtag cttactaaaa atattattca tcctcactta aacgtttatt
     4501 cattaatatt ctatcacatg acataaataa tttatatgat ttatatagat ttatttattg
     4561 taaattttgg aatattaaaa tattttattg aatagataat tatattacat aaaaaatccc
     4621 tatagaaatc tataaactaa tttctatagg gattttggtt aactaactat tctctttatt
     4681 tttttataac ttttatacct gtcatatggt catttaagtt ttgttcctct aaagatttat
     4741 catctactct gtttatttct aaagctaaag tttcagactt gatatattca ttaaaatggt
     4801 caacagcctt agcaatttca tcatcaccac agtattctat tactatatta tctaatactt
     4861 caaagttatt agattttctt aattgctgta ctttagatat aaattctcta gcataacctt
     4921 cattaatcaa ctcttcagtt agcttagtat ctagtataac aaaaagattg ttttcaacag
     4981 atacattaaa tccttcctta gcagttatac ctattaatac taaatcctta ttaaattcaa
     5041 aagcttcacc atctaaatca actgttaaag tctcaccttt ttcaagttta ttagcagttt
     5101 catgagcatt taatttactt aatgctccaa cgaataaatt catcttagaa cctaataatg
     5161 gccctgcttc cttaaagttt ggttttaaac taaagttcat atactcatct aaatccttag
     5221 caaatattac ctctttaaca ttaagctctt cttttattaa atcaactaca tcacttattg
     5281 tatcttcaaa cttaccatct actaacactt tttgtaatgg ttgacgaact tttattcttt
     5341 ctacttctct tgaagctcta cctaaagtaa ctaagttttt agctaaatcc attttttctt
     5401 ctaatttagt atctactaac tcttcattac atttaggata ttcagctaaa tgaacagata
     5461 cttctcctgt taagtttcta tacatttctt ctgacatata tggtgcaaat ggagctatag
     5521 ctctacaaag accatgtaac aattcataag ttgtattgta cactgctttt ttatcttctg
     5581 ttaattcagt tgcccagaat cttcttcttg aacgtcttat ataccagtta gataaatcat
     5641 catttataaa atcttgtatc attcttaaag ttttatttaa ctcaaatata gctaaatttt
     5701 cttctacatc tttcattaaa ttattgaact tagataatat ccatctatca agttctggtc
     5761 tatctttata ttctacaaaa aattcagttg gatttatatc atctgtgttt gcatataaag
     5821 taaagaagtt atatacattc ttcatagtac ctataaattt actttggatt tcttttaatc
     5881 catccatatc aaatttagtt ggagtccatg gtggagaaac atatagtaaa taccatctta
     5941 atgcatctgc tccatattgg tcaaataatt ccattggatt tactgtattt cctcttgatt
     6001 tactcatttt cttaccatct ttatcaagta caaggtctgg aactaaaaca ctcttatatg
     6061 gtgcttttcc taatacaaat gttgatactg caagtaatga gtagaaccaa cctctagtct
     6121 ggtctatacc ttctgatata tagtcagctg ggaacaattg gtcaaagttt tccttatttt
     6181 caaatggata gtggtgttga gcaaatggca tagccccact atcaaaccaa cagtctataa
     6241 cctctgttac tcttgtcatt ggttttccac atttttcaca ttttaagtgt atatcatcta
     6301 catatggtct atgaagttca actgtttctg gatttacatc ttctatagct ttttcagcta
     6361 attcagctct tgaaccaact gaatctgtat gaccacattc acatctccat ataggaagtg
     6421 gagttcccca atatctagtt cttgatattg cccagtcatt tagattttct aaccagtttc
     6481 caaatctctt ctctcctaca aaacttggga accattttac accattatta ttttctatta
     6541 atttatcttt aagtttagtc atctctatat accagcttgg ttttgcatag tatactaatg
     6601 gagtttgaca tctccagcag tgtggataat tatgaactac tttttctttg ctatataatt
     6661 tattttcaga agctagccat tttattattt caacatctag cccatcttcc attacaaatc
     6721 taccttccca aggagtagat gtaaatttac cagtttcatc tactggttga ataactggta
     6781 aatcatatct tttacctgtg ttgtagtcat cttcaccaaa tgctggtgct gtatgaacta
     6841 taccagttcc atcttcagta gttacataat ctcctactgt aataaaaaat gcttttttgt
     6901 caacttctac aaaaggcatt aattgttcat attctaaacc ttctaggtct ttacctttca
     6961 tttcttctaa aacttcataa tcttcaccta gtactttatc agctaaaggt ttagatacat
     7021 aatatacctc atcacctttt ttaactttta aataatctac atcagcattt actgttaatg
     7081 aaacgtttga tggtaaagtc catggagttg ttgtccatgc taagaagtat tcatcagcat
     7141 cttttttctt aaatttagct ataactgtat tagtttttac ttctttatat ccttgtgcaa
     7201 cctcatgact agcaagacca gttccacatc ttgggcaata aggaagtatt ttatgtcctt
     7261 catatatata tccttctttg ttgaatttgt ttagtatcca ccatacagac tctatatagt
     7321 tattatctaa agttatatat ggattatcta aatcaacttc ataagccatt ctctcagtca
     7381 ttattctcca ttgtttttca aatgagaaaa ctgactctct acatttttgg ttaaattcag
     7441 ctattccata ttcttctatt tgttgcttgc tagtaagacc taactctttc tctacttgta
     7501 tttcaactgg taatccatgt gtatcccaac cagcttttct ctttacttga taaccagaca
     7561 ttgttttata tctacaaact gaatctttaa gcgttctaga taaaacatgg tgtactccag
     7621 gatttccatt agctgttgga ggtccttcat agaatacgaa acttgggtca tctttccctt
     7681 tttctaaagt tttttcaagt atatttatgt ctttccaata atcaaaaact tgtgcttctg
     7741 cttgttttac agaactgtct accaatggct taaatttcgc catgtaaatc accctttcct
     7801 actaaatatt ataattccaa aattttttat tctttcacat aaatttaaat actaaaaaac
     7861 tcgccccctt taaaccaaag ggacgagtta taaatcgcgt taccacccta attctatatg
     7921 taaactaaat actagctaca tataacactc taatagtata acggtactaa ccggcacagc
     7981 ttagtagaat ttaatcgttc agcctgcagc tcaagagtga tttttatctt tataaattca
     8041 ttggttctca gcatacccaa ttctctgtaa aattatctaa agataaatgt ctctatcaac
     8101 gcttttaaaa atttatctgt gtttatatga aattctataa caaataattt gaatagtcaa
     8161 tatatttttg aaaaatataa taatttctat ttttcttaca tttttatcct atttttaatc
     8221 tttgttatag atttctcaaa ctcacacaat tattctacat aaaaaataaa caaattacaa
     8281 gcttattcta aagttgtagc agcttcatca ttactataat tatacactgt tgttccttca
     8341 aatgcgttta cacatttttc atctacatca taaaaaatct catcaacact tcttatttca
     8401 tcttctaaca gtgatttaaa tttatttcta aatatcttaa attctttgac taaagcatca
     8461 tactcttttc ttatctctat aacacggtta ttagcttgtt ctataatttg tctagctttt
     8521 aaatcagctt cttcaacaat tatcttagcc tttttattag ccgcactaca agtgtcttct
     8581 gctgcacttt gagcagttat taaagtggct tttagtgttt cttcaatatt ttcatacttg
     8641 tttacttggt cttgatataa ccctaatttt tctttaagag ctgtattttc cctacataga
     8701 gattcataat cttccttgat gatatctaaa aattcatcaa cctcttcatc tctataccct
     8761 cttaaacctt ttttaaactc tttattttct atctcaattg gagttagcat tacatttcct
     8821 cccagctata atttaaatta gtccttatac aattaatctt gcttgaactt ttatttttcc
     8881 ttttttagta atatctccta tttgtgttac cttagctctt cctttgcctc taatagaaat
     8941 caaatcatca ttttttacta ttttagaagt tgaagttatc ttttcataat tgacatggac
     9001 tttttctcca tttatgtatt ttgcactatc ttgtctagat atattgtaaa taccacttat
     9061 cacacaatct aacctatctg aagatactgt aaatgatact tctttatatt ttgaagaact
     9121 attaacaata ttttctctgg aaatttcctt tacaattaca ttatttcttg aaaccttttc
     9181 taagtttaca attataaaat cgcaaatatc actacttaca actacttgac aaaagctatc
     9241 atgtataatt atatctccaa ttttttctct ttttatacct agacccagta ttgaccctaa
     9301 gtaatcttta tgagatatat ttttaaattt gaaattccct tctatttgta aaaatctaag
     9361 agtatcttct atatcttcat attccatgta aaatggataa ataaatacag tgcttctttc
     9421 agctcgttca taacctccat ccacactgta ttttatttca tttgtagaat ttaatattgc
     9481 tacagcattt ttcacttcat atggattaag aaactccgta gacttaacat catagttttt
     9541 tatacaacta ttagccttgt ctatcacttt aaacatttta tttttcaagt ctatatcctt
     9601 tatgtgattt gttagtttta atttatccat cctatcacct tagaatataa ccaatactaa
     9661 ttgtcttagg aacatcaata atactattgc aattaaagga gaaaaatcta taggtccatt
     9721 tgtatattta tacattatag accttattgg cccttctatt ggctctgtaa gattttccaa
     9781 aatatcaaaa attttacttt gtcttccatt tggaaaccaa gtcatcaagc tttttataac
     9841 tatcatccat gctattatat ctaaaagata ataaagtgca attcttattg ttcccatata
     9901 ttaaccgcct ttttactatt tattttgcca agggaagaat gctttacttt ctaattcttt
     9961 tttcatattt gcatctatat ccacattatt aggagctagt ataaatattg atttagaaac
    10021 cttttgtata cttccatcta agacataaac tgccccattc ataaagttaa atatagattt
    10081 acgaacttca gaattagtca atccttccaa attcactata actgcccttc tttgttttag
    10141 atggtctgct atagttgcag cttcatcata aaccttaggt tcaactatta caactttcat
    10201 ttggctagtt gtatgtaaat ttacaatttt atttgctttt gtagtactaa agccactgtt
    10261 catttcttct tcttgaacta tatcgtccat gccactttca tattcatctt caatgtaatc
    10321 ttcttcttca tcaactatcc aattcttaaa tttagatatt attccatttg acattattaa
    10381 cttcctcctt aaaatttatt caaatttgag taattatttt ttattgtagt ttctttctcc
    10441 aaagattgat gttccaactc taacaatggt agccccttcc tctatagcaa tttcataatc
    10501 gtgactcatt cccattgaca aaacatccat ccctacatta gggatgttta gttcttttat
    10561 ttgttttgat aaatctttaa gacctttaaa tacacctctt atctcatctt catcttctat
    10621 aaaaggtgcc attgtcatta gaccctttat ttttatattt ttatattttt ctgacacttc
    10681 tttgacaaag tctacaactt cttctctatc aagtccatgc ttagactctt ctttagatat
    10741 attcacttgt actaagcaat ctatttctct gtttatttgt tctgcacgtt tttgaatttc
    10801 ttcgcataat gcaattctat ctaaagagtg tatcatacaa actttatcga ttatgtactt
    10861 aactttattg gtttgcaaag ttcctatcag gtgccagttt aatttatcac ctataatatc
    10921 atactttcta gctaattctt ggggtttatt ttcaccaaca gaagtgattc cttccctcat
    10981 tgcctcattg actaagtcta catcaacagt ctttgtgact gccaaaaggg taatctcttt
    11041 gctgtctcta tctacttttt ttgcagcttt atcaattttg tttcttatct cagacaaatt
    11101 atctttaata gaacccatta ttatcaccta ctttatcctt atatttgtgt ttatactgtt
    11161 aggtcttaaa attattttgt catatagatt aacacttgta actccattta tgtcattttt
    11221 ataataatcc acaaatacag aagattcatt ctcataagtt attccttcta atatgacaaa
    11281 ttttacactt tgtgattgtt catcaattac atatacacca cgtttattgt cttttgtttt
    11341 tatagaagtt ttaggtattt ttaaacattc catctgatta tatattatat caaattcttc
    11401 gacacttgta tcctgatttg caacaatttg gttacttatt tttaatttta ccattatttt
    11461 attattattt tcatatattt tgtaaacttt tgcatctaat ttttgctcat gatattcaat
    11521 tattacattt tgattttttt caaagttatt agaatcttct ttactgatgt atgtagatag
    11581 ataattactc tggtcattgg catctttttc tatacttcct tttacatgaa tctttgcatc
    11641 aactttttca ttttttaaca ccaacgtatt tacatttttg ctaattatca ttactaatat
    11701 attaaatact aaatatataa gaataccaag tatcactaat ctggtatatt ttaccttttt
    11761 caaagactct ccccctataa aattactttc attataagta cttcttctaa aaaatgttta
    11821 ttcctttttt ataagctaat attttacgtt ctaataatta ttttttccat attaaattta
    11881 ttttttatca atcttcctat acaagactgc attatttata tataattgta ttataaagta
    11941 taagtttaat ttacatttta tacgttaagc ttactttata tgtttttata gttattttta
    12001 tttttagata caatataaaa ccaattaaga tttaaaataa cttttgttat gttgacattt
    12061 atttaggtaa tcatttacga atcaggataa cgttatcata acaaaagttt atgtcctaaa
    12121 aaaaatacaa ggaggatttt cttatgtcag aaattttatt aggaacaggt ttacttttat
    12181 tggttctatg ttgtttcaca atttttagtt acaaggcccc atatggtatg aaggctatgg
    12241 gagctctagc aaacgctgca tgtgctactt tcttagtaga ggcattcaac ctttctttac
    12301 ttggtgatgt tttaggtatg gaatttttta gaagtgttgg agctgctaat ggtagtcttg
    12361 gtggagttgc tgctgctata cttgtgcctt tagccttagg tgtatctcca gtttatgcag
    12421 ttttaatagg attatcttgt ttagattttt ctatattatc tggattcgtt gctggatact
    12481 ttgtttcttt cttaattaag tttatagaga aaaaagtgcc acctggagtg gatttagtgg
    12541 ttgtaattct tctatgtgca ccactatctc gtcttatagc atcaaatgta gacccattag
    12601 ttaatagtac actactacaa attggacaag ttttgataga agctaccaac attagcccta
    12661 taataatggg aattatacta ggaggtctaa taacagtagt tggaacgtct ccacttagtt
    12721 caatggctct tacatctata attggtctta ctggtcttcc tatggcaata ggagcattag
    12781 gtgcttttgg ttcagctttt atgaactcaa cactatttgc aaaattgaaa ttaggttcta
    12841 aaaaagatat tatatctgtt gctattgaac cattaaccca atcagacata atttcagcta
    12901 atccaatacc tatatattct actaatttct ttggaggagc cttttctggt atcattgtag
    12961 ccttgatggg tcttgtaaac atgacaccag gtacagctac acctgtggct ggttttgcta
    13021 taatgtttgc ttataatcca gttcaacaag ttcttataac agctggttta tgtgctttat
    13081 tcaatgtaat tgcaggattt ttaggttcaa aaatattcag tacctttaaa gttcttactg
    13141 ctggtgaaat acgtggtact gatgtagaag aagaaattgc ttaaaaaaca ataagattta
    13201 taaatttata tctcaagtag tagagtttta tattgtaggc aattttatta attgcaaacg
    13261 ttttattttt tatttatgtt tatgattatt atgtgtgttg aatatttaga taaattttta
    13321 tttattattt ttatttagat ttttgtttag ttttttattt ggttgatata ttaggaataa
    13381 aaattagtat agtttattac tagttagata gcataacttt ttagatacat aaaaaatttt
    13441 atattaatta gatattatta aaataaaagc gatacatgaa tttttaaatg tccatgtatc
    13501 gctttatttt tgccataatc ttaacaacta atttttaaag tttattatct taacaaagtt
    13561 cattatctta tataatattt aaatgcatag acttctttaa tttaaccatc taaatattta
    13621 attaaatatt attatatgta atataactaa tttttaaatg aatgtatagg agctggaatc
    13681 cttcctcctc tttgagtaaa taattcagat gaatttgtat ttataggcat tactggtgct
    13741 cgtcctaaaa gtcctccaaa ttctaccata tcacctacat cacatcctgg ggctggtata
    13801 attctaacgg ctgtagtctt attattaatc atacctattg ctgcctcatc agctatcatg
    13861 gctccaagcg tacctgctgt agtatttcct ggcacagcta tcatatcaag acctacagaa
    13921 caaatagcag tcattgcttc aagcttatct atacttaaag cacctttaat aacagaatca
    13981 atcatacctg catcttcaga tactggtata aacgctccac taagtcctcc aacatgtgaa
    14041 catgccatta ctccaccttt tttaacagca tcatttaaaa gtgctaatgc tgctgtagtc
    14101 ccatgagtac caacaacttc aagacccatt tcctctaata tatttgctac tgaatcacca
    14161 atagcaggtg taggagctag tgataagtct attatcccaa atggaacatc caatctacta
    14221 gaagcttcct ttgccacaag ttgtccaact cttgtaattt taaatgcagt ctttttaact
    14281 gtttctgaaa caacatcaaa aggctctccc tttactttct ctaaagctct cttaacaaca
    14341 ccagggccac ttacaccaac atttataatt ctatcagcct caccaacacc atggaaagct
    14401 cctgccataa atggattatc ttctactgca ttacaaaata ctactaattt tgcacaacca
    14461 aaaccttttg catcttttgt taattctgca gtttctttta tgatttctcc catttctttc
    14521 actgcatcca tatttatacc acatcttgta gaacctacat ttactgaagc acatacttta
    14581 ttagtacttg ctagagcttt tggaattgac ttaattagta tcttatcacc ttttgtatat
    14641 cccttttgaa ctaatgctga gaatccacca ataaaatcta tacctaaatc ctctgcagcc
    14701 ttatccaatg tctgtgcaaa ctttacatag tcattttcat ctgttgcacc tgcaataatg
    14761 gaaattggag ttactgatac ccttttattt acaattggga taccaaattc acgctctata
    14821 tcttttccaa ccttcaccaa atctttagca gaactcataa tcttattgta tattttttct
    14881 ctagctttat ctccatcagg gtctatacaa tctaataaag aaatccccat agttatagtt
    14941 cttatatcca actgttcttc atctatcatc tttattgttt caagtatatt tcctacattc
    15001 actattatca cctcccctta ctgtctacta cagattatgc attgaattaa atatttcttc
    15061 tcgctgaatt tttacatcca ctgataattt cttacctctt tcaaccaagt cctcaaccgt
    15121 tttctcaaaa gaatttaatg atttctctaa atcaactatc ataatcatag taaaataatc
    15181 ctgtaatatt ttttgtgata tatctactat gttgatattt tgcttgtata attcatcact
    15241 aattcctgcc actatacctg gtttatcctt tccaattact gttaaaattg ctttcataat
    15301 aatatcctcc cttatttttt tataaatctt atatttttac aaattgaact atgtgttaac
    15361 atatatttca tttatttgtt agtaaaccac tttttatgta tatatttaat atattttaat
    15421 acctatacat tcatttgtca attttttttc aatattctat tatttttata ctatttagaa
    15481 aattcatata ttatatatgt tttctcaaca acaaatacag ttttcataat aatgaaaggt
    15541 attacttagc aatctcatga ttttctaaat aatacctttc taaaaattat ttttttaatt
    15601 ttatgaattt aattatactt tttctagtat caggatttac aattaatata gaaccaatca
    15661 taattggtgt tagtatacaa aataaaaaaa taatatcttt ttttagatta tattctttag
    15721 attctaattt ataattatta tttattattc catcataatc acttatattt gacttatttt
    15781 tatttgtatc ttgatttttg ttagaaatac tttccctata aggaaaagaa tgttcattgg
    15841 taccaaatac tgattttgag cttaaatcat aattatcatc attttctgta attgaatttt
    15901 tattgtaaaa tcctttttct ttatcagaat tattttcttt attaccatct ttaggtatat
    15961 catgaggatt tttattttca ttgctatcag tacttgattc tacatcatct ttaggagtat
    16021 ttggttgttt ctcatcagaa ttatcatttt cattattatt attttcatta ttattatttt
    16081 cattattatt gttttgattg ttattactat cattattttc atttccatta ttcccatctt
    16141 gattgttatc atcctcatct ctatccgggt cgtctctacc tcctcctcca cggtcaccat
    16201 caatatcatc attttcccgt tcatcatctg gtgtctcttg gttgtctccg cctcccatta
    16261 taaatcctgg tttaaaaact atatttgaat acccttcttt taatcctcct acaactttta
    16321 ctctaaaaca acgcaactta aaatcttcaa aaaaaagtat agcttgatct ctaatatcct
    16381 cctgttcttc agatatccaa ttgattccat cgcttgaata ttcaacaaaa accttacttg
    16441 cactatacgg catatcataa aataaaacag ctacatatcc attttttgta ttttgaaatt
    16501 ccagttccaa attgtctatt ggttttttct ctataacaga tacattcaaa ataggaacta
    16561 catcatcatt tattataatt ttttctttat ttaacatttc tgttttaaac tttcctgtta
    16621 tattaaaatt ttctcccttt tccaactttt cataataatc agtaaaatcc cattctacat
    16681 ctatatcaag tcgattacca ctagatgttt ctaataccat atatttggga aattttatat
    16741 tttctatttt atcatcttta cttactttta tttcatcact aaatacacca attcccctat
    16801 gacaacattt cacaatatca tagccagaat cttcagctat agagggtata agctcattat
    16861 aatcatcaat tatataaact ttcttacttt ctgatataat tgattgtgcc aacttattat
    16921 tatctcttag taacccactt tcattgttgc tactatatgc ttttattgaa gtttcttcta
    16981 tctcaacatc acctttagaa taaacaccta tagcatgttc tccattcact tcaatatcct
    17041 tatttagtat tctaatatca ttttcagtat aaattcctat tgcatctttt ccatttgcct
    17101 ttattttttc aacagattcg taggatgatt taatatgtaa gtctcctcct tcttcaacgt
    17161 ataaggctgt cccatcagta gcaattatgt tgtttatacc aatacttata cttccaccat
    17221 tttctatatg tattactcct tcttttcctc cttcacctat tatattcaat tcattatcat
    17281 caataataaa tctcccatga ttttttatca atattttata tttgttggta tctattgtaa
    17341 aattactgtc ataaggaata taaaatctaa actcttcatc tattaccata tcacaagaaa
    17401 gagtataaac tatttcttct ttattatttt tattttcttg aacccacctt tcaaaatctt
    17461 caagacaatt ttcctcttgt ccaaaaactt tatgtggaaa acttataaaa cacaaaacta
    17521 ttatactcat aaaaataaat atctcatact ttttcatctt acactcctag aaatttttag
    17581 ctttgaaaca atcctgtcga aacatatact tcacccacta taatttttcc acaattatca
    17641 attattgtca atttatataa gtatctttat taattgttat aaataaaaag ctacttacta
    17701 aagcaaacag acgtttcact ttaataagta gctatatttt tataacaaaa tagttataat
    17761 attagaactt ccttcattta caattttttg taaagtcttt tgcattttaa ctcttatctc
    17821 ttctggcata gtatataatt tactttgtaa ttgctctttt actaagtcat gtagtgattt
    17881 accaaacata tttgattccc ataaatctgc tggttgctct tcaaatactt ccataagata
    17941 ttttatcatc tcttcacctt gattttgatt tccaactatt ggagaaacct ctgtagatat
    18001 atctgctttt ataatatgaa gtgatggtgc attggctttt aacttgatac catattgttt
    18061 tccttgtttc attatttctg gttcttccag actaagttct tctaaggaag gagctactac
    18121 tccatatcct tttatcttgg catctattaa agcactttct attttatcat actcattttt
    18181 aactttagat agtctagtta tcagactaag cagttgataa tctccttcaa ttttaaatcc
    18241 acttttttct tcaaggacat tatagaataa atcttgcttt gtctgtaaat caatatttat
    18301 aacaccttct cctagctcta cattatcaac acctgtatct tccaaaaact ctaactcaga
    18361 aaatccttgt ataatacctt ctatatccct tattttacct atatctataa tactttgttt
    18421 taatgttgtt attatgctac tttttatcca atgatttctt tcaagacctt caacccattt
    18481 tggtaagttg attcttattt ctgtaagtgg aaaatcatat aatacagctt ccataacctc
    18541 ctctatatct tcttcttcca tttcaaccac attcattgga agaactggaa cttcatactt
    18601 ttcttccaat tcacttctaa gcatactcgt ttcctcactt tttggactta acgtatttaa
    18661 aaccactgca aatggttttt taagattttt caattcttgt ataactctct cttctggttc
    18721 tacatagctt tttctgtcaa ttccagtaac tgaaccatct gtcaagacaa ctatccctat
    18781 tgtagaatgg tcttttataa cttttttagt tcctatctct gctgcctttt caaatgtcat
    18841 agcttcttgt gaccaaggag tggatactaa tctttgtttt ccaccttcct catgccctaa
    18901 agctccttca actatgtatc caacacaatc taccattctt acttttaaag atactgtgtc
    18961 ttttattttt atttctacac catctgctgg tacaaatttt ggttctactg tcattatcgt
    19021 tttacctgaa ccactttggg gtatctcatc tcttgttcta tcctttttaa attcattgtc
    19081 tatattaggt ataaccaact tttccataaa ttttcttata aaagttgatt ttcctgttct
    19141 tacaggtcca actactccaa tatatatatc cccctgagtc cttttggata tatcttcgta
    19201 tatgttatta ttcatattat tcctcctata catctaatct tattaaatta tatttagagt
    19261 taagggttaa tattcttaaa atagaaaaat aaagaccagc aatattaatt taatttacat
    19321 atagaaattt gtaaatttca atgtaaatta aattaatatt gctggtccaa atagtagtgt
    19381 attatattaa ctgactttag tagtattttc atttgaatta ttattcatct caataagttc
    19441 tttacgtctt tcttttgtca tgttcatcca tataaatgta aacaccaatc caattatggc
    19501 tactatagta agaactatga agtagtacct atatccagtt acacccggaa atgcatccaa
    19561 tatcttccct gctgctaaag gacaaagtac ttctggaaga tatcctaatg tagcaactat
    19621 tcctatagca gttcctgata ttgataatga ataattacct tcttcaagta acgaatagtg
    19681 taaaccttga attgcataca tagatacata tattgcaaca catccaatca atagtatata
    19741 aatcatagat gattttgttg gtgtaaatat tacacctaaa agacctgcaa tcataagtat
    19801 aaatccataa gatataatct ttgatgaacc aactttatct ccaagtaatc cagaagcagc
    19861 tgatgctact ggtctacaat actgagctaa tattgagatt gcagatgcaa acaccacagt
    19921 agctccaaat gcttcagttg aataaggcgt aaaataataa aatgacatat tagctgaata
    19981 tgaacaaaac attattattg ttattatcca tgtatgaggc atttttatta ctgcaaaaaa
    20041 ggcttcttta tcaaattttg ctgatacctc tttttcatta tcctttaatt tgaaaaatac
    20101 taatactcca actattacat ttattgccga gtataatact ataatagctg taagaccaga
    20161 tttatcactt acttttgatg aaatataccc aaatagtatc aatactagag atagatgaat
    20221 tgcattggta attccacgac cactttccat aaatccaaaa gcttttcctt gttcattttc
    20281 agatgctaac attctaacag cttttacaag agctggccaa aaagtaagta ttgttgttat
    20341 tccccataag gcatggatta aaaacacaac aatatatgga ggataaagtg ttaatacaag
    20401 accagatatt cctgtaataa ttaaagaacc tgaaagcaat tttctggctg aaatacggtc
    20461 tgctaaaaaa ccaccaaaaa ggtatgatac cattgcaagt agaccataaa tacttcctaa
    20521 gcttcccatt tgtgtatttg taagattaaa tgcttgtgca aaagtatcat aataataatt
    20581 ctttaaatat ggtaaagcat atataaatgc tcctgctaca aagagtatta tcaagacttt
    20641 gaaatttttc caaatgcttg gtttatttac ttcaactgac atacttcctc cttatgtaaa
    20701 tacctgtaaa ttttcatgat aattaattat tgcttattgt attgtttatt caatatttcg
    20761 gaatatttat taatatatta ggttaatcta tcaataattt atggtgagtt atgagctaaa
    20821 agtaaactct tttagctcac cataataatt atatttttat ttatactaac gtccagagtt
    20881 attagatatc tttttttcat agttcttcca tagcattaaa cctgttatta taacaaaaag
    20941 acctcctcct atcatttcaa tctcatagat tatattatct tttaaagtct ccataactgg
    21001 tgccgttgag aaaagtatgc caactacagt tactacaagt accattctgg caatattgat
    21061 acaaactgaa tcactttttg caattgaata tggtctttct tcatttggtc ttgtctttct
    21121 aagtctaata taagatgtaa aaagcaagac atatggaaat aatgctgtta atgctgtcat
    21181 agtaacaaga acattgtata tattatctac tgatggtaat aagtttgttc ctacaagaag
    21241 tagactcact attatagcct gaactattac tgcatttgat ggtatattgt atttatttgt
    21301 aacagtcaat tgcttaggaa atacaccttc tcttacattt ccaaaaagca tctttactgg
    21361 acctgctata taaagtatta atgctcctag tactgataaa gttattccaa atgctactat
    21421 tcttataaac caacttccta tacctaaatc ttgtgcaact ttagctaatg catctagtat
    21481 ccctgtagat gctgcaattt tatctggagg aagtatcatt gttattgcta ctgaacctaa
    21541 gatatagatt cctcctatta aaacagccac agttaatata gctttaggaa agtttttctt
    21601 agcattatcc atttcggtta tgaaattagc agtcgtttca gctcctgata atgcaaatat
    21661 tatagcagat atagaaacta atgaattggc atctattttt ggtattatat tttggattgt
    21721 atatatcgat gctgatggag cttttttgag aataactaca gacataaatg ccatcactat
    21781 aagtaatata gcaggaattg tagaacctaa tgctcctgta ttcgtaaaaa attttccaaa
    21841 tgccatccca cgagtactta ctaaggacaa cagccaaaat attatgagtg aaagtgctaa
    21901 aataaacatc ttattgtttg ataaatctgg atttccaagc atatatgcaa tatttatcgc
    21961 taaaaaagtc aagaaagaag aataccaaaa tatctttgat gtccaattta gccatgacac
    22021 cataaatccc cacttctctc cataagcttg tttaacccat tctccaagtc caccatcttt
    22081 tggatatgtt gcagccaact ctgcacatat aagtgatgca ggaacaaaga atataaaagc
    22141 aaacaataac caaactggta tagaaccaag acccaatcca aaactagagg cagtagattt
    22201 agctatccat ctaatcccaa atagtgctga tatattcata aatactaaat cccaaaatcc
    22261 aattttcttt ttcactgtaa ttcctccaat ttcaaattta ttcagactca tacacaatgt
    22321 attgacttaa atatcaagta taagttcttc aacacttctt ggataattag ttataattgt
    22381 agcaccattc ttacctacta ttgctgtatc tgagtgtcta aatcctccaa ctccaggtat
    22441 atatatccct ggctccatag aaaataccat tccttcttct aatattaatt cattgtcaaa
    22501 tcttaaatat ggctcttcat gttctgataa acctaaacca tgaccaattc tatgatttga
    22561 atataactct agaccatact ttgcaacaac agctcttgct gcttcatcca ccattcttgc
    22621 tggtatacca gcttttattg tatctaatcc agcttgttga gcctctactg caatcttaaa
    22681 cacttctttt tgtctttctg ttggtttgcc tataataaaa gttctttcat tttctgctct
    22741 atagttttca taccaaacct gtctactatg tattactata tctcctcttt gaagtattct
    22801 agtattggaa tctaaatgag gttgtgctgt tctatcaatc cctgaacaag tccagtttgc
    22861 aaatcctata tatgtatcag gataattttc agaaacatat tttagtaaag cattatcccc
    22921 tgcaacgtca aactccaatt cactcatccc aactctaaca ttttctaaag acccttttat
    22981 tcctatatca gataggtaac ctgctatctt caaaaattct atttcttttg catcttttac
    23041 atatctcatt tcaaatattt tacttccaac atctttgata gcaaatgact tatcagttat
    23101 atactctgaa aagcttgcag atactatatc tttttctatt ccaacagttg ttcctttagg
    23161 gtatttattt aaaattatat ctaagtaatg tttatgtgat attccatgtt ctttcatttc
    23221 tggtatttca taatacacat atacattatc aacttttgca acttctttag catgtaattc
    23281 ttctaatcca ggtactatta attctatttt atcttgagtt actactgtta caattggtct
    23341 agaataagtt attgctttaa atccactaat ataaaattga ttgtctggtt caaatattaa
    23401 agcaatttca atgctttttt cattcatgta ctttctcaat ctttctagtc tcatattatt
    23461 tgacataatg cacctctttc ttaatattca gataatttat tcaatacaac aaggatgaat
    23521 atattatttt aaaattctta atatttttag tacttgtcgt atttgtatgt aaattaattt
    23581 tatttgtgat tattttatca taatcatgat tattttgtca atcatgattt tattttaaaa
    23641 aattttttat attctagtga ttttaaatta tctaaaatat aacgagtata cattgtattt
    23701 tgtaatatta ttcttgattt atggtaagtt taatgataaa atcacgatta tataaactat
    23761 attgattatt tgtaggtgaa taaaatgaca aataaagaat tacaaaagaa aaggatattg
    23821 atgtatttca tagaagctgc tcaaaatatt atggaaaacg aaggtataga aaatattaca
    23881 cttcgtaagg ttgcagatat ggctggctat aatagttcaa ctctatataa atactttaaa
    23941 aatttagacc atttaatatc atttgcatct ataaaatatt ttaaagatta taacttgaat
    24001 atttcaagat gtatagaaaa tgtcaatgat gaatataaga aatatataat tatgtggaaa
    24061 ttattttgta agcattcttt tgataatgct caagcttttt accaggtatt ttttaacttg
    24121 tctagtgatg aacttagcta tataacaaaa caatattatg atatgtttcc agaagattta
    24181 ggtattcatg atagtgacat atctttaatg attacaggag aaagtataaa ggaaagaaat
    24241 aagatactat taaacaacct tgtagatact ggatatatac cagctaaaga tttagacata
    24301 atcaatgata taattatttc tttttatcaa aatctattat tcttaaaaaa gaacacagga
    24361 aaaaattctg atgatgatga attaactatg aaaatgattt cttctattga atacataata
    24421 aaacatgcta aataaaatta aaatatggct gtctcaaaat agagataagc cttttttatt
    24481 gttgaaataa taaaaatata tttaatttca tataaaaaag agtgcctcgt aaactaaaaa
    24541 gttcattttg agacacccct aaaataaatt tattatttat tatacaatag tttatatatc
    24601 atcacctaaa actacttctt ccatttcatg ctttttactt ctcatcatta gttctattcc
    24661 aacttcttta ggatttgaac ctttctttat tacagaatat atagcattag ttataggcat
    24721 atctatatct aatttttcag aaacatcatg tgctacttca gtagcagtta tgccttctac
    24781 aaccatcttt acttctttta aagtatcttc taaactcata cctttaccta tgagtatacc
    24841 agctcttcta tttctactat gcatacttgt acaagtaact attaaatctc caatacctga
    24901 aagacctgca aaggtagaca tattagctcc catagcaatt ccaagtctgc tcatttcact
    24961 aatacctctt gtcataaggg cagcttttgc attatcacca taccctaatc cgtcacatat
    25021 cccagctcca aatgctataa tattttttaa tgctcctcca agttctactc caactatgtc
    25081 tggattcgta taaactctaa gtttagggct cataaataaa tcttgtatca tctgtgctat
    25141 ttttaaatct ttagaagcaa ctactacggt agtaggaata tcccttgcta cttcttcagc
    25201 atgagatggc ccagatagta ttacatatgg attttgtggt aattcttctt cacagacttg
    25261 agataatcta agcccagtcc ctttttcaag acctttagct acattaacaa taacttgtcc
    25321 ttcttttata aatggtttta ttttttggca agtacttctt acagcctgtg atggaactgc
    25381 taaaactatc accttacaat cttttatagt tttttctata tcagtactta tagttatatt
    25441 atttggaaat aatactcctg gtaaatagtc tgtattttct ttagttctgt ttattttttt
    25501 agcttgttcc tcttttcgag tccacatgct cacatcatta cctttttttg caagccctaa
    25561 agctaatgca cttccccagc ttccagtacc taatacacat actttctcca tgtttaacac
    25621 cacctgagta taatatattt actattcttt cttttgacca atttttctct ctgtcccatt
    25681 taataatcgc tttatatttg ctctgtgatt atatattact gatgcagtta agaacagagc
    25741 tactattaaa ccagctttat tttttaccat aatcataaat attggtgaac atcctattcc
    25801 tacaacagaa cccaatgaaa catactttgt tatagctacc accaatataa atactgctag
    25861 acacattagt gttattactg gatttacagc tagcattgcc cctagtgaag ttgcaacacc
    25921 tttgcctcct ctaaatccta aaaccgctgg ccaattatga cctgctacaa cacatataac
    25981 tgccagatat ccagctaaaa gagtatctat tccaaccaat cttgctgcaa attctgatat
    26041 taaaacagcc attacacctt taagaacatc acctaaaaat gtcattgctc ctgctctttt
    26101 tccaagtgtc ctaagtacat ttgtcgaacc tgcattacca gaaccttgag tccttatatc
    26161 aaccccagca attcgctttg caactatgta tgaggtagat atatttccta aaagatatgc
    26221 aactacagca ataattatat aactaaatat ctccactgaa tttcccccct ttagttatat
    26281 tttaagatat ttatttttta tttttttgtc tatactcaaa ctttatggaa gttccttcaa
    26341 atccaaaatt ttctcttatc ttattctcaa ggtatctttg atatgagaag tgagttaaat
    26401 ccttatcatt tataaacaat gtaattttag gaggtctaat gtcagtttga gtcccatagt
    26461 aaatttttaa tcttctacct ttgtcagatg gtggttgatt taacattaca gcttctccaa
    26521 ttacttcatt cagtgctgaa gttgatattc tcttagaatg ttcatttgac acatattcaa
    26581 ctgtatctag tatcttgttc attctttgat tagtttttgc agaaacaaat acgattggag
    26641 catacatcat aaatggaaat ttttctttta tatcttttgt gtaattactc atagtcttat
    26701 tatctttctc tattaaatcc catttattga ttacaaatat gcatcctttt ccttcatcat
    26761 gtgctatacc tgcaaccttt gtatcttgtt ctgttacacc ttctaatgca tctattacta
    26821 tcaatactac atctgctcta tctacagcac tcatagctct tattacactg tatttttcta
    26881 ttgtctcata tattttactt tttcttctaa gccctgctgt atctattaga agaaatttct
    26941 gtccattttt ttcaaaataa gtatcaattg cgtctctagt agttcctgca attggactta
    27001 caattactct ttcttctcca agtatcttat tgagtataga actttttcct gcatttggtt
    27061 tacctgttat agctactctt attatatctt cttcatactc tgtatctaat cctgctggaa
    27121 aattttcaac tatctcatct aataaatctc caaatcccat actattggct cctgaaactg
    27181 caaaaggcgt tccaaatccc aactcataaa aatcgtatat attatcaaat tgactttgac
    27241 tatcaatctt attaaccact aagattactg gtttttttgt ctttctaagc aattgtgcaa
    27301 tttctttatc agcagctgtt attccagctt taccatcaac tataaaaagt attacatgtg
    27361 acatgtccat tgcaagcatg gcttgatttc tcatttgaga taatattata tcttcgctat
    27421 caggttcaat tcctcctgta tccactaatg taaaatattt atctaaccat tctacttcag
    27481 caaatattct atctcttgta actccaggtg tattttcaac tattgatatc ctttttcctg
    27541 caaatttatt aaatattgta gacttaccaa cgtttggtct cccaactaca gctacaactg
    27601 gcctacttat actcatttta tttctccttc catcttttgt tttctatttt aaaattttat
    27661 ccacaaaatc ttttccttca ttcaaacaag ggataatttt tattctcata agttcttcta
    27721 attgatttaa ttcaatatta tctaagaaaa tttcttcatc tgcttttagc atacttcttg
    27781 ttatataaag agcttctcct aattctttat cttcaagttg ttcttttaaa tccttagctg
    27841 ttaaaagacc tgatacagtt attgtctctc caaaaaactt gtttttgatt tcatatacat
    27901 ttacttgaag atttttaaac ttgtccatca tagcatctgc catactctgt ataaattcat
    27961 atgcagaatg accagtagct attgatactt tcttctctct ttttagaata ttctcaggca
    28021 atatatttag atactcttca atctctgttt ttaacttacg tatcatacct acaccatctt
    28081 caaactgtaa aaaaccttca tattcttcat atccaggcaa ttcactatta gatagtatat
    28141 aaaattcatc tgataaaaat gcaaatcgag tacctaattt ttcaagatat ttctgttgta
    28201 tttgatgtat ttgctctata gttttacttg cgctcttatc attaaatata tttaattcta
    28261 ctagattttc tctatgcttt gtaatcccaa ctggaactat cgcaacactg tttacatatg
    28321 gataaagttg agctagttct tttattgttc tatccaattc ctttccatca tttatacctg
    28381 gacataaaac aatttgacag ttcatttcta tatgagcatc tgccaatctc ttcattatac
    28441 catataattt tcctgcaaat ttattgctta tcattttttg tcttaactct ggattagttg
    28501 tatgcacaga tatatttata ggacttattc tatattttat aatattattt atatcttctt
    28561 cactcatatt tgtaagtgtg acaaaatttc cttgtaaaaa agataatctc gaatcatcat
    28621 ctttaaaata aagagtttct ctcatacctt ctggcaattg gtctataaaa caaaacatac
    28681 acttatttct acagctttta gcttggtcaa ttatcggatt tgtaaattca acacccaaat
    28741 cttcatcata gtctttttct atctcgtata tgtagacttc gccatctttt ttttgtattt
    28801 ctacatctaa atattcatca cttagtaaga atctatactc tattatatca tgtattggct
    28861 gttcattcac agatataagt aaatctccta cctctatacc catttcttct gcaatactat
    28921 ctttataaac cttacttata atattattta ctttttttac atttacttcc aatattttca
    28981 ccactctttt gtattcatca atgcttatta taatgtattt taatatgcaa tttatttatt
    29041 tgttatattt tatgatagca tttttaagca tttcatgtca taataacaca ttttaattct
    29101 aatagtcaat ataagtaaat agctataaaa tagattagaa caaataatat tcaaatttaa
    29161 gtttcttaaa aatttgaata ttatttgttc ttaaaaaaat tttataaatt taatgtttta
    29221 ctatgattaa cgtcccattt gtcatatcat gaaccattcc acctacacac tttgacatca
    29281 acaatgcctt attttgtaag tctttctcat catttgcata aaatattgga caacctccac
    29341 catttttcat attcttatcc aacgtaacta tagctagtgt atattcattt aaacctatat
    29401 ccattcccat cttatgcact tcctttcttt cctattttat aattttttag tgataagttt
    29461 tttcctttag aacttgaaag tattgggcat gactttacgg cttccattac tttttccaca
    29521 ttcttatcta ctggtaaata agcaatcatt atactttcat cctctttatt ccttctaggt
    29581 aatggtacga atgaaggttc tccataatct ccatataaac ctaaccttga atatatattg
    29641 tatactattg cctgtctttg acctgagtca aataatatcc ctgcattagc ataatcttta
    29701 tttttaggaa ttatttgtat tcctacacct ctattaatat atacttctct atcacttttt
    29761 agacctatat ttgttattcc ctttaaatct cctaccttca atatagactc atctacaaaa
    29821 ctaatctcag caggcattac atcagctatg tctccaatac tttttctagt aagaagtttt
    29881 tttaatataa aggctaacac taatccacaa attgaactta ttaccaaact cattccttca
    29941 cttattttcg tttctgcaag tattacataa tacaatccta ttgttaaaaa agatgtaact
    30001 atacacatat aatttcttac ttcataggtt ctagctatct cttctatgaa tgcagctcct
    30061 ctctttacaa gttgaacttc ctctaagttt tgcaatgtat ttcttctatt tgctctcact
    30121 tgtctaaatt gctctgctgc tagggataaa aaagttatag atgtataaga acgatttata
    30181 agagctggaa ccaataatgc tcctaatgaa gaagcgacga atgctaatat aagttgagat
    30241 agtaaaacat ttggttgcgt tggatactgt ttttggtcta aattcaacat tataattcta
    30301 gatgttatac caataataac agcaacaaaa aatactctat ccattaaatc actcctaaaa
    30361 tatttaattt gaaattttac atgtaaatct acaaagtctt tctagaaaaa tcactctgct
    30421 ttccttttga tgtttctatg ataggtgtac ttttcactac atctatcatg acatctatat
    30481 ctttgagtat tggcatatat ggtataacca cagtactttt ttctaaattg gtcttagata
    30541 tagcaacaat atcaacctca tctacatctc tatctatccc catatgaata aatagattat
    30601 gtattatagc ttgtctttgc cctatatcat ttactattcc aaatgcacct aaatctcttg
    30661 gtataacttc tatagccaga cattcatttc tatacttttc tcttgtactt tctagaccta
    30721 tgttagttat tattacacca tttaccatta aaataggtcc ttcaaaactt atttttgcag
    30781 gaactatatc tgctatatct gctatactgt tccttcttaa aaatcttcta aaaatcaaac
    30841 caacaatagc tcctgacaca atagctaaga ttgtgcaata aaaaaagcta aggccatact
    30901 ttcttgcaaa aacgatataa actatcgaag ataccagtgc agaaaaaaga cttatataac
    30961 ttctagattc atacgtagat gctatttctt caacgtaagc gtctcctttt ggtactaatt
    31021 cttcattatc gatattcttt agtgttattc tttcttgttc tgcaagacct tgaaactgtt
    31081 gtattgctac tgcaaaaaat gtcaaggctg caaactcctt atctataagt gcaggtaatg
    31141 ctatagcacc taacgaagct gaaagcccag atataattat ctgttctaaa taatcttgtg
    31201 gtcttgatgg gtattgtttg tctgtaactc ttaaaactaa tcctctacat aatattccta
    31261 caactaatgc aactataaaa gagtgtctaa ataaatttgc attcaataaa ctttcttcca
    31321 ttttctcagc tccttctctt atatagtttg tgcaaaaaac aaaaaaaatt cccttctatt
    31381 taaggaaatt tttttgtaat attgtaacta taaattcgct accaatgcca agttcacttt
    31441 ttacttttat acatccattt agtgatttga ctatatgctt tgttatagcc aatcctaaac
    31501 ccgttcctcc tacatcccta cttcttgctt tatctaccct ataaaatcgt tcaaatatgc
    31561 gttctacatc ttcttttggt atccctacac cattgtctat aactttaatt acgatttttt
    31621 cttcatcttt taacactaca acttgtacaa tcccattatc ttgggtatac tttatagcat
    31681 tatcaactag gtttaagaac acttgcttta tatagtcttt attggatagt atacttattg
    31741 atttatcatc acatttatat aaaacttcta tatttttttc actagctgaa tgttgagtta
    31801 tttcatatac ctctttaaat acatcatata ctacaacatt ttccataaga agagtatctt
    31861 tattttctac aaatgataac agcaatatat catcaatcaa cctttttaat ctatctgatt
    31921 cgctttctat tatttctaag aatctatttc tagtattcac atctatattt tcatttgact
    31981 ttagtgtttc aacaaaccca cttatagatg taagtggtgt tttaagttca tgacttacat
    32041 ttgcaacaaa atcacttctc atattttcaa gtttaacttt tttagtaata tcttctatat
    32101 ttactatcga acctattatt acgttgttag tattctgaag ataaactggg tctactttta
    32161 tcttatatac gatatcatct ttagtagtaa tattagcagt ttcattatct ttagaaccaa
    32221 taaattgaag tatttgtttt aatatttctt cttcttttat tacaacatta atattatgac
    32281 cttcaactaa ttgatttggt tcactcttta tcatttcttt tgcttcatca tttatcagaa
    32341 gtatatttcc atttacatct atagctaaaa ttccatgaga tatactcttt aatatagacc
    32401 ttagctgtaa atgtttatac tgtacttctt ctaaggtttt atccatattc tttatcatat
    32461 gattaaaatt tctagctaat tcgccaagtt ctcctttggc tgatatgtta agcctagcat
    32521 gatattcatt attacttact ttttttgaga cgtatataaa ctcttttaaa tatttcctta
    32581 atgttattgt gtatcttaca gctaatataa caatggctat ggacaacata acaataaaaa
    32641 aatatatact atttaaatct tccacaagat aacactccta aaatataacc tttttaatct
    32701 attttgtatc ctacacctct tatagtctct atatattttt ccgatttatc ttcatcttct
    32761 attttttttc ttaaatatct tatatgaaca tctactgttc tagtttctcc atagtattca
    32821 tacccccata ttttatccaa aagataattt cttgaaagta cttttccttt attttgaatt
    32881 aataatttta acaattcaaa ttccttaaga gttaactcta tcttttcaga gcctttggta
    32941 acttcatgtt ttgataaatc tagttttaaa ttacctgtag taagtatatt gttttcttca
    33001 cctaagctag tcaaattata tctccttaaa acagaactaa tcctagctaa caactctttt
    33061 atactaaatg gcttagttat atagtcatca gcacctattt caagcccttc aaccttgtca
    33121 ttttccatat ttttagcagt aagcattata acaggaatat tttttaagtc cttatcactt
    33181 cttatttttc tcaaaacttc tattccactt atatttggta acatccaatc taaaagtatt
    33241 aaatctggtt taatttcctt agcctttata aatccgtcaa atccatcata tgaataacta
    33301 acttcgtaat ttgacacctc caaattgaat tttaatagct caactatatg catttcatcg
    33361 tctataacaa gcactttagt attcattaaa aagctcctct ctattttatc tgtagtaccg
    33421 ttcctattcg ttctgatgcc ttattatgtt ttctataaga gtggaattta tctgctctac
    33481 aactagtgca taaatttaaa tttattatat tttctttttt aactccacta catctaagca
    33541 tatactcatt aattttccat aaatctaaat agtaacttcc ctcttttatt atatagaact
    33601 tttcatcatt atttgtaaga attgtgttaa atttttctac taaatcttca gacacttcat
    33661 aacaacatgg tccaattgat ggtccaatta tacatactaa atcttcagga actgttttat
    33721 agcattcaga cattaatttt attgttttat gacctatatt actaaaagtc cctctccaac
    33781 ctgcatgagc cagtcctatg gctttatttt tagcatctat aattgatata ggtacacagt
    33841 ctgctgtaaa cagtaaaagt ggtacttttt ccaagtttgt tataagtgca tctccatctc
    33901 ttcttttccc tatagtatct ttattgacta tattaactat atctgaatgt atttgagaat
    33961 tactagttag attttcaaat gtcaaatcac attctttaca tacttttaac atatcttctc
    34021 tattttttgc atctatattc ttacatgtta taactagatt tacagaattt aatttttcat
    34081 caagttcttc acaattacca cttaaattaa catactcttt aatatcttgt acatttttta
    34141 tatttatata atctttcatc atttgtctcc tttttctatc agtatacttt taagttcatt
    34201 tacaaaagta tttatatctt taaattgtct atacacagaa gcaaatctta cataggcaac
    34261 ctcatctaac tctttcaatt tatccattac catctcaccg atttttttgg tttcaatttc
    34321 ttctataaaa catttattta tttcattttc aatatgtaca acaatacttt caatctcgtc
    34381 aatagaaaca ggtctttttt cacatgcttt taacaatcca tattttatct tttctctatc
    34441 aaaatattct ctactattat cctttttaat gaccattaaa ggagttgttt ctattttctc
    34501 atacgtagta aatctctttt tacatgattc acactcacgt cttcttctga tagattttaa
    34561 atctgtatgt ctagaatcta ttacctttga ttctttataa ttacaataag gacattgcat
    34621 ctatattcct cctttgttta actatatctc aaactcatct aagcttaatt ctgaacctat
    34681 atttactatt attgtatcac aacctatttt aagtatatca ttccaaaata taacttcttc
    34741 atcccctcct cttgaaaaaa aacttctact tccatctcca aaaatggtaa atgagactac
    34801 cttaccttcg tgaatatcca tgtctatgtc tattataaac cccatccttt ttccattttt
    34861 tacatttata atttcttttt ccattatatc agaaactcta atcatattgt actcaccctt
    34921 tctttaaaaa taaatatgta tcgaagtaaa aaaaaatgac ctatataggt catttaaatt
    34981 aaaataatgt ttacagtcca tggattactt atacatattt tctcatattc tttaaagcat
    35041 ttttttcaat tcttgatact tgtgcttgag atataccgat ttcatcagca acttctatct
    35101 gagttcttcc tttgtaaaac cttaaatcta ataccaactt ttctctacta tttaatttct
    35161 taatagcttc tttaagtgat atttcttgca accaattttc atcagtatct tttttatctt
    35221 gaacctgatc cataacgaat attgcatctc cattgtcttg atatactggg tcaaacagag
    35281 atattgggtc ttgtatggca tcaagtgcca ttacaactga ttctacttct aattctaatt
    35341 cctttgctat ttctgatact gtaggttctt tagaatttgt tctaattaat ctttctctaa
    35401 cttgtagtgc cttatatgct atatctttta atgacctact tactctaatt gggttattgt
    35461 ctcttagata ccttctaatt tctcctataa tcataggaac agcataagtt gaaaacctta
    35521 cattttggct taaatcaaag ttatctatag cttttataag accaatacaa cctatttgaa
    35581 ataaatcgtc tatattttct cctctgttgt taaacttttt tattacactc aagactaatc
    35641 ttaaattccc tcttacaaac tgttgtctgg cttcttcatc accatttttt atttgtaata
    35701 aaagttcctt catttgctta tttttaagaa ctggaagttc tgatgtatta acaccacata
    35761 tttcaacctt attaacttgc atatattttc agtcctctct caaaagtatt catctattga
    35821 aattatttac atttccaatt tttttatact ttttaagaag aattaattta tcattataca
    35881 aattttttca tttctttttg caaccttgag attattttct tttcaagtct agatatgtag
    35941 gactgtgata ttccaagcat tccagcaact tctttttgtg ttttttcaat acctttatca
    36001 ataagaccaa atcttaattc cataatttgc ttttctctgt cacttaatct gtcaagtgcc
    36061 ataaccaaca aatctctatc tatttcttct tcaattattt tgtatatttc atcattttct
    36121 gtacccaata catcagataa taaaagttcg tttccatcta aatctatatt taaaggttca
    36181 tcaaatgata cttctgtttt ctttttatta ttttttctta agtacattaa tatttcattt
    36241 tctatacatc tcgaagcata agttgccaat tttatatttt tattcagttt aaaagtatta
    36301 actgctttta tcaaacctat agttcctatt gaaatcaaat cttctacatc tatacctgta
    36361 ttttcaaatt ttctcgatat gtagactact aatctaagat ttctttctat taaaattgac
    36421 tttacacttt catccgtttc tagcttttgt aaaagctcca tttcttcttc tggtttcaat
    36481 ggaggaggaa gtatatttgc ccctcccata tagtatattc cctttggctt tattattttt
    36541 aatttaatac ctaacatagt aataaagctt attattcttt ctttcaatcg taacattcct
    36601 tgtccccctt aaattttcac ctaaaatcca ggcaatatat ttggattcat tattgctcca
    36661 tattctctat cattaaaatt tgaaatacca agtattatat ttcctatctt ttgctcatct
    36721 acttctatat agtcagcttt taagcctatt attatgcttg tcttattact tccagcatgt
    36781 ttataaggta ttattctaac tctacctgaa gttttatcat ctaaacttcc tataatttct
    36841 tgtgctttct tcatatctat atcttcataa ttaatattta atagtttttc tggaataaat
    36901 ccttctaaca cactagactt aactattatt acatcacttt gacttattgg gtcttttaac
    36961 aaattaccac tatctactaa agccttacag caaaaacttt tttctagtaa gtttatattt
    37021 atagtctttg taagctcctt aatgtactta agcattttca aatctttata aatgtatttt
    37081 aataattcac aactcacata agtacatgca attaagaaag atatttttaa gtgacttatt
    37141 cctgtaaaat aaattataaa ataagtgctt ccagaaataa aaatgtttac tagataaaaa
    37201 actaacgcta catgaacata atcttttttg ctcttacttc taaatgaaat taaagttatt
    37261 atactcatga ttattatttt aaatggtaca gtaaatagta tattcattga tggatacaaa
    37321 taagcaacag aataggcacc tcctaaacta gcccccaata acttattttt tttaggatta
    37381 tatcttttag taagaataga agtacaactt ataataatat aatttattac taggttttct
    37441 ataacatagt actcaatata caccatgtat ccccccttaa aacctttaaa catattataa
    37501 gatagtatgt acaaaatttt atgtcacttt tgatggtcga atccaaaaca aattctattt
    37561 aaaaagaaca atgatatatg tcttatactt tatgtcgtca aaagatattt ttttaatacc
    37621 aaacaaatag acttttttgt agaatccaat atatctaggt agaagttatt cgctctactt
    37681 ttggtatatt tacaaaaaaa gactacataa tttaataata tatcaagtaa atcttttact
    37741 tatataaaat caaattatat agtctgtaaa ttcaaatata aattattgtg ctagtaatcc
    37801 atttgcatat tttgcagatt catttagtgc ttgttctgga gttatgtctc cagctatcat
    37861 catttgaagt tgtttccata aatattcata tatctctact ccatgaggtc caactgtcaa
    37921 tggtctatac atatgtttat ctcttgtcac catttcttca aatcttgggt ctccttggta
    37981 tttttcacct ttagcaactg gagctctagg tatttctttg tggaaagctt ccattgattc
    38041 tttgcttagc atatactcaa gaagtttaaa tccaagttct ttatttttac atgctgacat
    38101 taatgttaaa tcatctactg aagcaaaact tccaactgtc ttatcttcta atgatgttac
    38161 atatccccag tttaaatccg ggaatgattt atcaaaagta cttgtagcag cagaggatag
    38221 cattatagta aatgcagctt ttcctggtcc aaatacactt tcaatcattt cattactatc
    38281 ttttgataaa gcatcttctg gaatatactt tttcatatca tttataaagt ttgcagcttt
    38341 caagccttct gcattattaa atttaactga ttttaaatca tcattatata tatctccacc
    38401 agcttgccat aaatacggat accagttcca gtttaagctt ccaaatactt tagaacccca
    38461 accttgtgca agaccccact ggtcgatttt tccatctcca tcagtatctt ttgttgcttt
    38521 ttcacagatt cttttaaaat catcccatgt ttttggaggt ttttctccta atttttctag
    38581 tatatcttta ttgtagtaca atacgcctgg attagcagct tctataggta aaccataaat
    38641 accacccatc atttttgcat catctaagta tagataatta tctgaagttc ctgatttttc
    38701 taaataaggt gttaaatctt ctaccgcacc catttctata aattgaggaa acatctctgc
    38761 atacatgtat cctatatctg gaccttcacc tgcacttatt gctgttgcat atttttctgc
    38821 gtagttatcc catggtacta tctgaaattc aatttcacag ttattttctt tttcaaattt
    38881 ttcaaatatc ggcttccatg catctgcatc atggtctgtt aatggtgcag accatacaac
    38941 taatttttct ttaccctctt tgcctttaga atcttctttt tttgaacatc ctgcaagaat
    39001 tgatactgat agaatcccta ccataactaa agaaagaacc ttttttagtt taatcatgct
    39061 taatcccctt tcagacttta atttgtcttt ttcctcaaat gtttacattt aattcagatt
    39121 taatattaac aaataagatt actcttgtct aatcataaaa aactatacta actcctataa
    39181 ctatattttt tttctatacc tattagattt aattcatact aaaaacttac tttttaaatt
    39241 ttatcaatat ttaaaaatat ttttaagtct agccacaaac taactatcta aattgaacaa
    39301 aataaaaaga agtctattga cttctttata agcttacata ttatcttctt cttcttagga
    39361 atgtaggtat ctccatgctc tcatcatcat cttcttcaat tatacttgcc tttttaggag
    39421 gctctatttt ttcctcagca attacttctt cttcaatttc ttttacagct tgttttactg
    39481 ttgtatttaa tgaagaacgt atgcttgatt taggtttagt atctaaatct aaggcaccat
    39541 tttgtaatcc ttcaaatcct gtcgcgatta ctgtaatcat tatttcatca cctaaatctt
    39601 cttttataga agctccaaat ataacatttg cttctgggtc acaggattcc ataactaaag
    39661 ttgatgcctc attaacttca aataatccta agttaggacc acctgtaaca ttaagaagta
    39721 ctcctttagc tccttgtatt gatgtttcta gaagtggaga ttgaatagct tgtcttgcag
    39781 catcaattgc tctagtttca ccactagcac tacctatacc catatgagca agtcccttgt
    39841 ctttcattat agtagtaaca tctgcaaagt ccaagtttat taacccttca actgctataa
    39901 ggtctgaaat tgattgtata ccttgtttta atacatcatc tgcaactgca aaagcatcta
    39961 acattgatgt atttttttgt actatctgta aaagtctatc atttggtatc gttataagag
    40021 tatctacttt tgatttaagt tctgctattc caccttcagc gttcttcatt cttatcttac
    40081 cttcaaatgc aaaaggtttg gtaactacac ctactgtaag tatccccatt tcttttgcca
    40141 agcctgcaac cactggagca gctcctgtac cagtaccacc gcccattccg gctgttacaa
    40201 agaccatatc agctccttga agtaacttta ctatttcatc tttactctcc tcagcagctc
    40261 tttttcctac ttctggattt gctcctgctc caagtcctct agttagtttt tctcctattt
    40321 gaactttata ttcagctttt gatgtatata aagcttgttt atctgtattt actgatataa
    40381 attcaacgcc ttttagttga gcttctacca ttctattgac agcattgttt ccaccgccac
    40441 ctacacctat tactttaatt tgtgcacatt cttctaattc tacgtcaaag tttagcatca
    40501 taaaccccct tctctcatga ttcaaagtta tcgtatgtat taattatatc attttcttct
    40561 tttattttgt taacctttaa gtaacatatt ccacaaaaac gtaaattttc ctttttaaat
    40621 ttcttactta tattgtcaaa tattactctt taagtataaa ataatttacg tatatattaa
    40681 atgctcttta atttttacgt tttttattca taatattact aataatatat cgtctaatta
    40741 tagataagtt attaaacaat ctcataccaa aaactaatac agcaacatag taaagagaaa
    40801 ctcctaactt ttctcctata taagtcaata atatagccaa tatagcatta cctatgaaac
    40861 cagtaataaa aattacatta tcatagttat cttcaaaatt ggattttatc gctccaaaaa
    40921 tagaatccat tattgcaaga atagctactg acatatatat ggaataatcc atagaatatg
    40981 taaatggaat atagtaacct actactacac caaatgctaa tcctcctaaa acccataaca
    41041 taaatcttca cctctttatt ttactttgaa acacaactac attacaatcc tttttattaa
    41101 ttttttttac tttttcttta tttttttgta tttttcgttt tattttgcaa ataaattcac
    41161 tttatttcca ttattttcct gaacttttat attaattcca tatatatcct taagagattt
    41221 agcatatgat tctggagagt ttatagctgc actcaataaa tctatatctc ctatagcttt
    41281 tattataaat ggttgtccat atgtagtatc atttactgta atagtagctc ctgaacattt
    41341 tatcttactt gttgctagta ctctttctcc atttatagaa attgctcttg ctccagcctt
    41401 ttttaaatca tttaaaactc tcaaaatatc tatatcatgt ataatcaaat cgtttggatt
    41461 ctgtccgtct tttaattctc tctcactatc cctcatagta atagttatgc ctggccctgt
    41521 aatagttgaa taaccactta attctttaac ttcttcaagc tctttttgca taagtgtttg
    41581 gatagattca tttccattct tttttgcttc tttatattca ttcaaagttt ttttgttctt
    41641 tttaagagtt tcttttaagt tttttatttc tttttttgta ttttctacct cactttcaat
    41701 actttcagtt tgacctaatg ttatgtatac tctatttggg tctagtgatt ttatataagt
    41761 tgatatgaaa acacctaata tgaatgctcc taatataact attttctttt tcatactatt
    41821 atttcccctc tgctttgttt atatcactat gaccatttat ttctatattg tcttctttgg
    41881 tcacttttac tttggcatta taatatgttt ctatttccca gacaatacca tactttatat
    41941 taagtgccga agccaatgta tcagaatcac caattgcttt tattataatt ggttctttta
    42001 tgacagtgtc attcatataa agcttgtctt cttttaaata catatatgta ttagaaacta
    42061 ttctctggtc gtttatagat atggcacttg cttgtgctga atttaactta tttatcattg
    42121 acaataataa atcataatta tatagtatac tatcattttt atcagagttt cctaagtctt
    42181 ttgtagaatt tatctcaatt tttatgcctg ttccttcaac atctgtatat ccagctaatg
    42241 tttcatattt ttctatttct gacttaagta tgtcttgttc tccttcatta tttttgcctc
    42301 tataagtctc tatatctttc ttcacactat taacttctga ttgtagattc tctttttctt
    42361 tttttaaaga tttaagttct tctgtaagtt gctctcctct tttaaaagtt gtcatccctc
    42421 tattttctat attaataatt ttaagttgta aactaacaag aacacccaat acaatacttc
    42481 ctatgattat acttttattt ataaatcttt ttttcaatat atcacttcct tacaattgtc
    42541 tatccttctg gactatacac tgccaacttt ccatagttaa gatttatagt ccctccatta
    42601 gtatttttat tttgcaggtc aatcagaatt ttacttaccc tagatatatt ataatctaag
    42661 ttatcatcat tagaaagtaa gatttttata ttacttcttg taagcatttc tatattgctt
    42721 tcttttttta agtttacata atttattttt ctataaattc cttcttcttt taaataattt
    42781 aaagttttaa atacattctc cttagtttta taatttttaa attttataga tttattatca
    42841 tcaatgctat aatctacatc tactatcaag tcttttttac tttcattaga acctcttagt
    42901 tcttccaata aatttccttt tttatctata taacaataat tatcttcatc ttttaatact
    42961 gcaaatattt ctttttcttt taagcttata attatcttat tgggaagttt tctttttatt
    43021 tccacatttt ctatatatgg attttttata agtttatttt tcatatcttt aaaattgtat
    43081 gcaaaaatat tttcatttag atttacattt agttctttca ttatatttga tttggtcacc
    43141 ctcttatttc caattacatc tattttcttt acatcaaata aatcactttt tacaattata
    43201 catatacaaa aagataacat aagtataaaa actaaaacta tcatgacatt attcgtattt
    43261 aactttcttc tttttttcaa atataatcaa cccctttggt taataaatac acctttagag
    43321 cttgtttttc ctacaaaaaa attataatat ttaaagtcaa atttttgcat tttattacat
    43381 aacatccaaa taaggtatta aattttataa ataaatcaat atttcatcaa aatagacata
    43441 gcatactaca tactatttat atatttaaat ctgtatacat acaaataaac ccctaattta
    43501 taataattta gaaaatctaa tatattataa attaggggta aatatttact tatcttttct
    43561 ttattcctat taccttagct tgaccttcta tacttggagt cgtttctttt tttatttctt
    43621 ttacttcctt aataactttt tctttttttg tttttttaga agttgacttt tgtgttgaat
    43681 tgtatacttt cattatctca tcatatataa ggtctatggc ttcaggctta cctatagttt
    43741 tacttgcatt tgccatatca accaaaagtt ctctatctcc taaaagttta aatactgctg
    43801 tatttaggct ctctggagtt agattttttt ctaaaatagc aattcctgcc ccttgttttt
    43861 ctatactctt ggcattatac tcttgatgat tttcagcagt ataagcttta ggtattatta
    43921 tagatggctt tccaagagcc gttatctcag ctaatgaaat tgctcctgcg ctacctataa
    43981 ccaaatcact tgctgcaagt gcatttgcca tatcttctaa gtaaggcaca actttttggt
    44041 atggtttaag atttatatcg ctaatacttc ccataaattc atcataatag cttttgcctg
    44101 tagcaaatat aaaagctata tcttcattta ccatattctt tattacaagt ctcattgcat
    44161 catttatttt tcttgaacct ccactaccac catagcaaag taccattctt ttttcgtcac
    44221 ttattgatag attctttctt gcaatatttt ttcttgataa taaaatttct tttctaactg
    44281 gatttcctgt aaaaactaat ttatcttctg ctgcctctgg aaatctttta tgcgaatctt
    44341 caaaacttgt aagtaccttt gtaactgttt tagataaaat cttattagtt acaccaggaa
    44401 aagaattttg ctcatgtatt atggctggta ttttccccat agatgcatta aataaaacag
    44461 gtccactaac atatccacca gttcctataa ctatatctgg tttaaatttc ttaacaatct
    44521 ttcttgattg ctccaaacct ttaaaaagct taaaaactct ttttacatta tcgaaatcta
    44581 tttttcgctt aaaaccttga actgttacag tctttaattc aaatccatac ttaggaacta
    44641 tttctgactc tattcccttt tccgtcccaa caaaaattat ctcagcgtct ggatgctcat
    44701 ctcttatttt gtttgcaata gctatagctg gatacacgtg ccctccagtt ccaccgcctg
    44761 ataataaaac tttcatcaaa tcatcatctc ctgttaatta attttgacat gctttgagat
    44821 gtttaacact attcctacag ctcccataaa gatggtgagt gaagttcctc cataacttat
    44881 aaatggtagt gctacacctg tagctggcat tgatgatgtc gcaactgcta tatttaaagc
    44941 tgcttgtatt ccaatttgtg cacctatacc tataacaacc atacaagcaa atacattaga
    45001 agtcttcaaa gctattctta cacatctgta gactaaaact acaaatagca taataactat
    45061 tatacaacca atcaatccta actcttctcc tattatagca aatataaagt cattttgtgg
    45121 ctctggtata taaaaatact tttgtttact ctttcctaag cctagaccaa acaatccacc
    45181 tgaacctagt gcatatagac cttgtattac ctgatacccc ttaccaagag ggtcttgaaa
    45241 agggtctaaa aatgatgtaa cacgactaag tctatagggt tcagcaatta ctaatgcagc
    45301 aaataaagca gccccactcc ctatcatagc aaatacaatt ttcatatcca ttccagcaac
    45361 aaatatcatt acaaaagtaa ctagaattac agtacctgct gttgacaaat ttggctgaag
    45421 tattatcaac gcaaaaaata tccctggaac tacgagaagt ggtacaacac cttttgtcaa
    45481 agattttatt ttatcataat ttttttcaat taattttgca gttaatatta ttgtagcaaa
    45541 ctttgcgatt tctgcaggtt gaaatgttaa agctcctatt cccaaccatc tttttgctcc
    45601 gtttgcttct atccctaaag gggtcaaaac taacaataat aatactactg ctatagctcc
    45661 aattgctgta gcatttttct tccaaaaact ataatctatt cttgatgtaa taatcataac
    45721 tataaatcca agtacagcat atattacatt cttttttaga aaatagtacg catcattgtg
    45781 tttaaatgaa gattgtataa aacttgcact aaacaccata actattccta caaatactaa
    45841 aagcatagta gtgtaaaaca ctactccatc aaattcagtc ttcatcctta tgtcaatttg
    45901 ttttttcaaa ttttctttag gcatccaact aatctacctc cattcttcca tttaagtaag
    45961 tttagaggta agagattatt ttaaattgtt tacattatct ttgaagtctt ttcctcttac
    46021 ttcaaaactt tcatacatat cccaacttgc acaagctggt gaaagaagca ctatatctcc
    46081 actttttgaa atttcataag aagtcttaac tgcttcttcc atatctttta ctatatgtat
    46141 gtcattaaat cctttatttt tagcacaatt ttctatattt gatgcagttt ctcctaataa
    46201 gaccaatgat ttaacatatg actttgcagt ttcaagaagt tcatcaaaat tacttccctt
    46261 atccatcccc cctgctataa gtattatagg tctatcataa gactgtatag cttttatagt
    46321 ggaatctgga ttagttccct ttgaatcatt tacatatatt acattgtcta aatttcttac
    46381 aaactcttgt ctgtgttcca ctcctttaaa tgtcataagt acgtccttta taacttctaa
    46441 atcaattttg cagacatatg ctattgctat agctgccata caattttcta agttatgacc
    46501 tccaggtaaa cttacatcat ctttatttag aaatttgatt ttatcatcta tatctattat
    46561 tatgtcatta ttttctaaat atactcctcc atttactttt ttagttcttg aaaagtaaat
    46621 tactttggca ttgcatttat cagctaaaga ttttactatc tcatcatcat agtttaatac
    46681 acagaaatcc tcaacagttt ggttcataaa tatatttgcc tttgcttcta tgtatttttc
    46741 catagtatgg tgtctattta aatggtcctc tgtaatattt aatattgcgc ttactttagg
    46801 tctaaattca tctatactct caagctgaaa actgcttagt tcagttacta acacagactc
    46861 ttcacttgaa gtttctatag tatctattac aggatttcct atattaccaa ctacatatgt
    46921 atctcgtttt gctcttgaaa aaatttctcc taccaaacta gttgtagttg tctttccatt
    46981 tgtacctgta atccctataa aaattggatt attcgatagt ttaaaagcta attctacctc
    47041 accaattata tacttgcctg aattttttaa tttcaatatg aatggtaggt ctagtggtac
    47101 acctggagac actacaacca tatctatatc atctacatct tctgggtgat gtcctaatat
    47161 gtattttatg tcatttatag atttcaattc atcaagtata tttctcaatt tattttcatc
    47221 ttttatgtca tttacgatta tacttgcacc caatttatct aaatgtttaa ttgtagatat
    47281 accagttttt gcaagtccta ctaataaaac tttttttcct tttaagtcca tttttcattc
    47341 cccctagccc taaaatactg ctattatact tatccaagct aaaacaactg ttataatcca
    47401 aaaaataaat acaactcttg tttctggcca accacactgt tcaaagtggt ggtgtattgg
    47461 agccatctta aagaatctct ttcttgttgc cttaaaatat ccaacttgaa tcaaaactga
    47521 tagagcctcc gcaaaataaa ttcctccaat tataggtatt ataagcactg agttagttag
    47581 aactgaaaat gctacaactg cacctcctaa tgccattgaa cctgtgtcgc ccataaacac
    47641 tctagccgga tatgaattaa atcctaagaa acctaaacat gctccaacag ttgctgctgc
    47701 taaaactgcg acttctgtat ttccagcaat agaacttgca aatagcataa agaatacaga
    47761 aactattaat gttactcctg atgctaatcc atctaatcca tcagtcaagt ttacagcatt
    47821 tactattgct acgattataa acatcattat tggtatatat aatattccaa catttatcac
    47881 aaaatctgta aatggtatca taagttgtga agcacttgat gatgatgtat actgataaaa
    47941 agcaacataa aaagataatg caacttgaag gattattttt tgatatgctt ttagtccaag
    48001 tgatcttttt agctttattt ttataaaatc atctaaaaag ccaataaaac caaaacctgc
    48061 aatacatata agacctactg ccatatcatg actaactttt actcttgtaa gtccagttat
    48121 tagaattgca acaatcatta taattccacc catagtaggt gttccgtttt tagctagatg
    48181 tgtttggggt ccatcatctc taactgtctg accaaattta aattttctaa gcattggtat
    48241 aaatattggt cctattataa ttactattaa aaacgcaatc aatgcggtgt acgtaagctc
    48301 tgttattcct aacatcataa aactcctctc ccttgtcaat taactcatta gtttaagctt
    48361 atttatttag atattcgact attttttcta atctcatgcc tcttgagcct tttactaaaa
    48421 tagtgtctcc tgtttttact aattcattta acttgttaaa cacatcttct ctattctcaa
    48481 agtgatatat attggctgaa ttgaatccta attgttttgc ttcttctcca ataaacactg
    48541 aattttcacc tatagttatt ataatatcag tattattcat agatgatttt ccaactaatc
    48601 tatgaccata ctctgaaatt tcacccattt ctagtatatc tccaagtatc gctacccttc
    48661 tacctttata tcttccaagt atctttaaag cagcatccat agaatctgga ctagcattat
    48721 atgaatcatt aattattgtt aatttttcat tttttattat gtctaatctc atttttgtcc
    48781 ctttaaaatt ttttaaacct ttttttatat aatctaaaga aatatttaga cacaaaccaa
    48841 ctaatatagc agacattgca ttatatatat tatgttctcc tattgttggt ataaatattt
    48901 cctctttttt cccatttatt acacatataa atgttaaact atcctcttcc atagtataac
    48961 tttcacaata aacatcattg tttttattaa agccaaatgt ttttaactta tatgcatgtt
    49021 ctttttcttt taatgtagat aaaaacttat catctccatt tacaattaaa gtatttgttt
    49081 catcaaagtt tgaagtaatc tccatctttg ctttcaaaat accctcttgt gaacctagtt
    49141 tttctacatg tgataatcct atattcgata tgactgcaat tttaggattt actatatcca
    49201 ctaaatattt tatttcattg aatccagaca tacccatctc tattacagca cactcatgtt
    49261 ctttatttag attaaataaa gtcaatggaa ctccaaaatg attatttaag tttttttcat
    49321 tttttagtat atttaacttt gcagatatgg cagagtaaat catatctcta gtagtagttt
    49381 ttcccacact acctgtaaca cctataaatg gaatatcaaa tttttcttta tagtattttg
    49441 aaatatctcc tagagccaaa gatgtatctt ttacctctat taaatttata tccgaacttt
    49501 ctaattttat tccattactt tcatttttta taaaagtttt acatccacta tcatatgcag
    49561 acttcataaa tgtatgccca tctaaatttt ctccaactat ggctacaaat gcattttggg
    49621 catttgcctc cctgctatct ataactatat cacttacaca gtcattataa tctccatata
    49681 ttaacttccc attagttgca agtactaact cttttattgt taagcactcc attattaaac
    49741 tcctccttta aaaccttagc tatattctct tagcaacaaa aggcaatgta taccgttata
    49801 tatacattgc ctacgataac tcttaacttt ataattatat actatatttc tgtttttttg
    49861 aagatgttta tgggtatatg ttaattatct gttacttttt agttttcaaa atatagggtt
    49921 atacttgagt cttcattaac ttttactcca ggttttggga atatatcctt tacctttgta
    49981 tcttctggaa gttctatatc tgcatctaag tctggtttta acttcgcatc ctccaatgcc
    50041 tttacagcat ctcctatttt tagatttctt acatctggca ctttaacttg cttcttttca
    50101 tactcagctt tttcttcttc tttatatact ggtttaactc ccaaatattt taaagagtca
    50161 ttcattattt ctttcactat tggtcctgct gtagtactac caaatgcact tactcctgtt
    50221 ggttcgtcaa caatagcaag aactactatt tgtgggtcat cacaaggtgc gattccaaca
    50281 aatgaacata tatactttcc tggagcatac ttaccatcta taactttttg agctgtacct
    50341 gttttaccac caagtctata acctggtata tacgctatct ttcctccacc ttcagttaca
    50401 actgattctg caatttctaa cattttttta gatgtttctt tagatataac acttcttact
    50461 ttttttggtt ttactgtttc agttatattt cctttattgt cagtataaga ttttaccact
    50521 cttggttgca ttaaatctcc accattagct attgatgata tagctgttat aagttgtatt
    50581 ggagttactg atatagattg accaaatgat attgtagcca attcaactgg tcctacattt
    50641 ttttcgttat acagtattcc cttagcttct cctggtaaat ctatacctgt cttatccata
    50701 agaccaaatg attctatata atcatacatt tttccaacac ctaatctgct tcctaactca
    50761 acaaatactg ggttgcaaga gttttgtact gcttgtttaa attcttgtgt tccatgaggt
    50821 ctgtaatgtc tccaacattt aatctttctt cctccaacag ttacactacc tgtacatgtg
    50881 aatttttctc catctttaat tactccttct tcaagagcac tggaagatgt aataagctta
    50941 aatgtagaac ctggttcata tgtatcactt actgctggat ttctccacat ttgataatag
    51001 ccttttattt tatctttatc attatatttt tcaagttctt cttgataata tggatatatt
    51061 ggcgttcttg aatcattagg gtcataatct ggttttgatg ctaaagcaag tatatcacct
    51121 gttttagggt tcatagctat tgcagtaact ttttttgcat tatttaactc ataagctttc
    51181 tgtactgctt tttcagtata gtgttgaatt acttcatcta tagacaacac aagaccatta
    51241 ccttgtacag gctcataata tttttccatt ccttgtggta tttctcttcc tgaagcatca
    51301 gtacttacta taagttttcc aggctttcct tttaactttt tatcatattg catttctaca
    51361 ccagatatac ctgttgcatc tgaagaagta tgtcctaaca catatggtgc aaaattccca
    51421 tatgggtaat atctttgatt atcttctgcc acccatattc cacttaattt agcatctctt
    51481 atttgacttg ccttatcatc atctatccat ctttttactt ttacaagagc catatttttt
    51541 ttgcttatta aagcgtaaat atctttataa tcttcatcca aaatctcagc taccttttcg
    51601 gctgcttctt ttttatcttc tacttccaca ggtttacacc aaacagtata cttagttaca
    51661 cttactgcta actctttcat atttctatca tatatagttc ctcttttggg ttctattggt
    51721 atatctcttg tttgttgttc tagtgctttt gtactcaacc aatttccctt cataagttgt
    51781 agatacccag tcctaataac aaggcaaaaa aacaatgcac atgctagaat aagaacgagt
    51841 accagccttt tcttacttat cctctttact tttctcaaat ctattccccc tagttatcca
    51901 catctatata ctttatttgt ccatcttttg gatagtccat attgagcaat tccttagcct
    51961 ttagctcaat ttcttttatt gatgtttttt cagtttcttt tgcctttagt tcctctaata
    52021 ctatctcttt ttttcttaaa tctttttgta aataatagat atcgtacttc atttccgaga
    52081 tttttgaata accacataga ttcaatatta ttactgaaaa agttgcaatc agtaaaatgc
    52141 atttagctcc tatttttttc ttatttctct ttttataatt attctttttt ttatttttat
    52201 attcatttag attatgtatt ttataatttt ttttcaaatt ctcaccccga tagtatatag
    52261 tttaaatttt cctctatact atatttgtta ttaatcatat ttcttcctct aaaatttcat
    52321 cgctaaatta atacactatt acacaatcta attgtatttt tttctataca caacaaaaac
    52381 ctataaattc acttatactt ttatatgaat ctataggtta gatattaatt tctatttatt
    52441 tttatcactt ctagtatttt tagataattt cttccataaa tataatatgt aactaactat
    52501 ctactctctg attcctaagt tctccattat attacttaat accatctata tctatatttt
    52561 tatatctaaa ttttcattat atatctcaat aacaaagaac atttcttata gtgttaattg
    52621 ttttttaatt gctttaccag tgcaacaaaa tatataatac tttttaatta attataataa
    52681 tcttatttta tatataagat tattctttag ccttataact acttatattt tttctgctac
    52741 tcttagctta gcacttcttg aacgtggatt tacttctatt tcttcctcac taggtaatat
    52801 aggttttcta gttattattt tcacctcaga ttctttatca cattggcata taggtaaatg
    52861 ctgtggacat atacaatctg atgctaaatg cttaaatgca tttttcacta ttctatcttc
    52921 taatgaatgg aatgttatta tacatattct tccaccttca ttcattatag aagaagcatc
    52981 atttatcatc tttgtaatta ctccaagttc attatttact tctattcgta ttgcctgaaa
    53041 agttctttta gctgggtgag gtccatctat tctagctttc ttagggatag cttttttaat
    53101 tacatctact aattctcctg tagtttctat tggtttgttt gctctttctt caactataaa
    53161 tttagctata cgcttagccc agttatcttc tccataatct tttattatct tagttaattc
    53221 atcttctgta taagtattta caacatcata tgcagaaaac tcacacctaa catccattct
    53281 catatcaagt ggtgcatctt gcatataaga aaatcctcta tcagcttcat caagttgatg
    53341 agatgaaact cctaaatcag ctaatacacc atcaattttg taaactccta ttttttctaa
    53401 ttcctctttt atattttcaa aattactgtg aacaaacttc actctacttt catattcact
    53461 caatctctct tttgctgtgc ttatagcatt tttatcttgg tcaaacccta taaataatcc
    53521 cttatctgac agttttttta ctatttcttt agaatgtcct gctcctccca tagtacagtc
    53581 aacatacacg ccatctggct ttatatttaa attctctata cactcattta aaagaactga
    53641 tacatgatga aattccatag ttacctccct taaattcact ttttaaacta ttcttcacta
    53701 atattatttt tatttttctt tgataaataa acatgtgcaa ttatgccacc aataactcca
    53761 attagactta taacttgtgc cattctaagt ggtcctaaca ttaaactatc tgttcttaat
    53821 ccctctataa aaaatcttcc tattgaatat aaagttatat aagtaactat aacttgacct
    53881 tcatattttt tattttttct aaatagtaat aaaactataa atattccaaa atcccatata
    53941 gactcatata aaaaagttgg atgtaccttt actccatcaa ccattattcc ccaaggtaaa
    54001 ttggtagcac ctccatgtgc ttctccatta ataaaatttc cccatcttcc aatagcttgt
    54061 gctaaaggca ttccaagtat aactgtatca gccattttta agaagttaat atttttaatc
    54121 ttagtgtata tataaccagc taatattcca ccaattaacc ctccatgtat agcaagtcca
    54181 ccacctctaa aattaaaaat ttgagacata ttttgagcat agtaactcca attaaataca
    54241 acataataga ttcttgcaca gattagtcca actggaattg ctattatagc tatatttaat
    54301 acatcatctt ctttaattcc cactcttttt gcttctttta ttgctattaa agttcctaaa
    54361 atcattccac atgccataag tattccatac cacatgatgt ctatgccaaa cagtgtaaat
    54421 gctactctat ccataacgtc acctctttgt attaattgaa aatatttcca aagcaatatg
    54481 ctataattac aattaattgt aattatacta aattatgata acacattaat gttaattcta
    54541 caaaaaatat taaaatttat tctacaactc cctacactat attatatcta attactataa
    54601 aattttttaa actgaatctc tcatgactaa agttacaagt gtacatagat attttttaat
    54661 caaaaagatt gatgcatata tacatcaacc tcttctaatt cttatctata gctcttaaat
    54721 ttttacctca atttatataa atatatttta taaatttgtt ttaccaaaat aaacatttaa
    54781 aaacataaac taatacttaa ttagttattc ttattatgat taagtttcta tttaggctct
    54841 acaatagaaa taacacaata ctcttcttta aaatgctctt ttaatctttc ttcaacttcc
    54901 tcaaaagtaa tatctttaat aacatctaaa tactccaata gatttatatc cttaaaaaca
    54961 taagatataa aactattacc tataaagttt atagaatcaa agcacttaat aaatgaccct
    55021 atttttttct ttttagttct ctcaaactct tcttttgata atccttcttt ttttgatttt
    55081 tctatataat caagaattat ttcttttact tttttaggct ctttagaatc tccagctatt
    55141 atgctaaaag cataatccac ttgagacgaa aatccagctc caaaattttc atttattaaa
    55201 ccttgcatat acaaatcttc ataaagctta cttccttttt taaataacat ccctacaagt
    55261 atatcagtta caatctcttt acgtaaaagt tctttccctt ttaaaccaac attactatct
    55321 ttaaaaccta tgttgaacat aggcatagat atagggaatt tttctataac ctctttttct
    55381 tttacacctt ctggttcttc tggataaaat ctttctatac tcttagagag tctgtctact
    55441 ttgtaattgt ttgacttttt agttacatct ataacttttt ctacatctaa gtcaccaaca
    55501 acaaataaag ccatatttcc tggattatag aaagtattat aacatttata tagctcttcc
    55561 ttagttatct tatatatact atcaacagta cctgctatat caattctagc aggataattt
    55621 acatacattg ccttcaagca attaaagtat acattccaat cagggtcatc attgtacatt
    55681 tttatctctt gtgctattat acctttttcc ttttcaacat tttcatctgt aaaataaggt
    55741 gtttgaacat agtcaattag atgttctaaa ctctcataaa aattttcagt agcagaaaat
    55801 aagtaggctg tcattgtaaa attagtaaat gcatttgcat ttactcctaa ttttgaaaat
    55861 ttatcaaatg catctcctcc atcaggttgc tcaaacatct tatgctctag aaaatgtgca
    55921 ataccttcat tcactctaat tttcttatct tctccaattg gtacaaattc taagtcattt
    55981 gaaccataat tagtagctaa aatagcatac tttttcataa aacccctttt aggcataaaa
    56041 tatacatcta atccattttg caatttctca taataaactt cttctttcaa tatatcatta
    56101 actatttttt ccatagacat ctcctccatt aatttctcaa gaagtataca gtatcaagct
    56161 ctatattttt tatagcttca actatatctt tttttgtaac cttttctata ctagatatta
    56221 tgtcttgtac ttcagaattt gtctttgcca tagattgaga gaaaacaaaa tcagacatac
    56281 cacctatatt atcagttata gatttcatag aattaactaa agcaagttta ctgttttcta
    56341 attcttcatc agatatatca cctgctttta cactttctac ttgttttttt atcaattcta
    56401 cagctttatc ataatcttta gtttctatac cagatgatat aaacatgata cttttatact
    56461 tctctattga agagaatata tagtaacata aactttcttt ttctcttaca ttaacaaata
    56521 atttagagtg tggaccacca cctaagacat tgctcccaac tactaaagca taatatttat
    56581 ctatgtctgc ataatccaca tttgctctat aacccataac taacttacct tgagttattt
    56641 ccatttgttc atctataact tttacctcat ccacattttt tataaaatct gctcttggta
    56701 tatttataat ttcttctctt tcaaatttta gatttttact tattatatct acaactttat
    56761 cttcatcaaa attaccttct acaactatat ctataggtga tgttttaagt atgtttttat
    56821 aatgttcata taactctctt gaagttatac tatctatttc atcttcataa ccaaattcac
    56881 ttacactata tctctctcct ttacacatag cctcaataca tttatcttgc gcatattcct
    56941 ttttatcatt tattattgat tgtatctttt ctcttaaatt ctctttttca atatttaaat
    57001 attcttcttt aaacccacca tctacaacaa gcgtattatt tattacttca ttaaaaaatt
    57061 ctactacttc ttcaaatata ctctcatcta aatacttttc acttatgtta attactttaa
    57121 aactcaatac ttgacgttct ccacgtttta cagcatcagc tcccatagat gaaccatata
    57181 aatcatctaa tttattggat attgctctag cactaggata tttagcgctt ccacttgcta
    57241 ttattgatgg tattagagca ttttttgtag tttctttttc atccaatagt ctctgaacat
    57301 ataaacttat aagattcgat ttaaactttt ctgtttttat caaagtaaga ttaatattat
    57361 tacctaaatt tattattttt ttagtattaa ccatatgtac ctcctatttt tatttaaaca
    57421 tcaattttaa aattgaaatt tatttatttt ttaattacat atactcacat ataaaaacct
    57481 tctatttaat tatatccttt ttattatttt ctaaaagcaa tatttttatt taaattaaat
    57541 acaaatatta tttaaatcaa tatgctttaa agtctagttt acaagcttga tatatatgat
    57601 gtataatcaa tatgtatgtc tataattaaa acaattttgc aatcctatag attgattgtt
    57661 taaagttata taaagaatat aaaaaagaat aagagagagg acgattaata tgaaattagg
    57721 catagttggt ttaccaaatg taggtaaaag cacactattt aacgcaataa ctcaagcagg
    57781 tgcagaatct gcaaattacc ctttttgtac aatagaccca aatgtgggag ttgtatctgt
    57841 tccagatgaa agattaaaca aactacaaga attatataat tctgaaaaaa tagttcctac
    57901 tgctatagaa ttttgtgata tagcaggttt agttagagga gcttctaaag gagaaggttt
    57961 aggaaataaa ttcttatcac atataagaga agttgatgca atagttcatg ttgttagatg
    58021 ttttgaggat gaaaatgttg tacatgtaga tggttctgta gacccacttc gtgatataga
    58081 aactataaac ttagaattaa ttttctcaga tatagagatt cttgaaagaa gaattaataa
    58141 aactcaaaaa gctgctaagg ctgataaaac tttaggttct gaacttgatt tattaaaatc
    58201 aataatgtct actttagaag aaagtaagtg tgtaagaact atggaattta cagaagatga
    58261 acaaacattc gtaaattcat tggatttact tacatctaag cctgtaatat atgcttcaaa
    58321 tgtatcagaa gatgatttag ctgataatgg agaaaataat aaatatgttc aacaagttaa
    58381 agcatttgca gaaacagaag atgccgaagt tgttgtagta tgtgcacaaa tagaagcaga
    58441 aatttctgaa cttgattctg ctgaagaaaa gaaagagttt ttagaaacat taggtcttga
    58501 acaatcaggg cttgataagc ttataaaatc ttcttatgct ttacttggtt taatttcatt
    58561 cttaactgct ggtccaaaag aagttagagc atggactata aaagttggaa gtaaagctcc
    58621 tcaggcagga ggaaaaatac attctgatat agaaagagga tttatcagag cagaaacaat
    58681 agcctttaat gatttggttg agcatggtac tatggctgct gctaaagaaa aagggttggt
    58741 taaattagaa ggtaaagaat acatagttaa agatggagat gtaatattat ttagatttaa
    58801 tgtttaaaat gattaatcgt atacactttg actattatat ataataacta aaaaactaag
    58861 attataataa tacaatatta tcttataata attatatag
//
LOCUS       DAEOTL010000014        58853 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEOTL010000014 DAEOTL010000000
VERSION     DAEOTL010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58853
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.014"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            69..413
                     /locus_tag="KRH82_001180"
     CDS             69..413
                     /locus_tag="KRH82_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBG8654470.1"
                     /translation="MEIKRYEGTGRMSRTVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(572..2668)
                     /locus_tag="KRH82_001181"
     CDS             complement(572..2668)
                     /locus_tag="KRH82_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBG8654471.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPLIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPFEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTVITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(2681..3841)
                     /locus_tag="KRH82_001182"
     CDS             complement(2681..3841)
                     /locus_tag="KRH82_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBG8654472.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSNFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(3860..4927)
                     /locus_tag="KRH82_001183"
     CDS             complement(3860..4927)
                     /locus_tag="KRH82_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBG8654473.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            5279..5845
                     /locus_tag="KRH82_001184"
     CDS             5279..5845
                     /locus_tag="KRH82_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654474.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(6064..7050)
                     /locus_tag="KRH82_001185"
     CDS             complement(6064..7050)
                     /locus_tag="KRH82_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBG8654475.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(7080..7775)
                     /gene="pxpB"
                     /locus_tag="KRH82_001186"
     CDS             complement(7080..7775)
                     /gene="pxpB"
                     /locus_tag="KRH82_001186"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBG8654476.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(7795..9015)
                     /locus_tag="KRH82_001187"
     CDS             complement(7795..9015)
                     /locus_tag="KRH82_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBG8654477.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(9044..9835)
                     /locus_tag="KRH82_001188"
     CDS             complement(9044..9835)
                     /locus_tag="KRH82_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBG8654478.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            10423..11052
                     /locus_tag="KRH82_001189"
     CDS             10423..11052
                     /locus_tag="KRH82_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654479.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(11166..12680)
                     /gene="glpK"
                     /locus_tag="KRH82_001190"
     CDS             complement(11166..12680)
                     /gene="glpK"
                     /locus_tag="KRH82_001190"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBG8654480.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            12924..13466
                     /locus_tag="KRH82_001191"
     CDS             12924..13466
                     /locus_tag="KRH82_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654481.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSYISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            13480..15972
                     /locus_tag="KRH82_001192"
     CDS             13480..15972
                     /locus_tag="KRH82_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8654482.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            16393..16791
                     /locus_tag="KRH82_001193"
     CDS             16393..16791
                     /locus_tag="KRH82_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8654483.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMMILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(17008..17217)
                     /locus_tag="KRH82_001194"
     CDS             complement(17008..17217)
                     /locus_tag="KRH82_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654484.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(17249..17458)
                     /locus_tag="KRH82_001195"
     CDS             complement(17249..17458)
                     /locus_tag="KRH82_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654485.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            17757..18176
                     /locus_tag="KRH82_001196"
     CDS             17757..18176
                     /locus_tag="KRH82_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654486.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            18404..18859
                     /locus_tag="KRH82_001197"
     CDS             18404..18859
                     /locus_tag="KRH82_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654487.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(19015..19827)
                     /locus_tag="KRH82_001198"
     CDS             complement(19015..19827)
                     /locus_tag="KRH82_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBG8654488.1"
                     /translation="MAEQKYYTLLTKAGKASIANATALGKKVDLVKLQLGDGGGSEYS
                     PTEEQTSLKEVVWEGNISNVKIDDDNSNWIVIETVIPGSIGGFMIREVGIFDSENKLI
                     AISKYPETYKPTADSGSVKDLIIRIILVVSNTSSVNLKVDPTVILATLKDIQELDKKI
                     DTTKITLTSGIETTKIELNTKIDNTKTDVTSKIGDTTLLNTTDKTSLVNAVNEVKEGL
                     DSIETTAEKTSYDNTVSKLAATNVQGAIDELCTSVNTARISLINDIKDMLPI"
     gene            complement(19829..20446)
                     /locus_tag="KRH82_001199"
     CDS             complement(19829..20446)
                     /locus_tag="KRH82_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBG8654489.1"
                     /translation="MKLIDKLPSFYKNYMVEAIQDSYDSELSSLKENIDDTINQMFVN
                     TSTWGLDMWESILCIQNNEDLNYETRRSNIKAKMRSLGTTKLKVIKNICEAYTKTDVE
                     VTVLSNEFIFILEFIVNNCSYNSIVELDKVLENVKPCHLEHKFKMILLNKNELFCGTA
                     INTGETVTVYPWTPSNIEIFGEITISTGNDRSMEKVILYPKQEAI"
     gene            complement(20446..21495)
                     /locus_tag="KRH82_001200"
     CDS             complement(20446..21495)
                     /locus_tag="KRH82_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBG8654490.1"
                     /translation="MYSNQTYETIKNRTLKNINLDVYKGEGSFLNDMVSGNTFELSKM
                     YVELSNIYKMAFIEDTYNQLLDKRVNEFGVYRKLGTEATGEVEFIGENGVEISNGTII
                     SYKDLSFVVIKDIVIGGEEGNISPVEALEIGTRYNLPSDCEFKVNDNIFGIEKITNIN
                     KFSGGTEIETDEELRERFFRVQKNQATSGNKAHYEEWALEVDGVYNAKVYPRWNGAGT
                     VKVLLFGQNNQAVEEEIITKCREHIEEEMPIGATLTVTTPIPLNITISASMELESGYT
                     LDMVKNSFIENINQYFRSITGEIVYTKIMGILISTSGVHDLSNLLVNNSTDNITIEDD
                     KIPSVTTLDFSEVEV"
     gene            complement(21488..21919)
                     /locus_tag="KRH82_001201"
     CDS             complement(21488..21919)
                     /locus_tag="KRH82_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBG8654491.1"
                     /translation="MSNTIFPFIGVPEDYEIPKKEELGLFREVAWNFEKDEPIVENGD
                     FKIIEKNEAIKVWVYKCIKTNKNEHEIYSNDYGTELTDLIGQKYSKGLTESEASRYIK
                     EALLMNPYILQVDVVNTNFKKDILGAYIKISTIYGEVEINV"
     gene            complement(21919..22245)
                     /locus_tag="KRH82_001202"
     CDS             complement(21919..22245)
                     /locus_tag="KRH82_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBG8654492.1"
                     /translation="MANSINEFIGIIRKEGKYYNKPSFFVGKIINKLPDLKVSMNNIV
                     LDKDNLLIDNWLFDRATKSFIITQSNNHTHELNESLTNQLDKGDTVIMFKVGEKFAII
                     SKLVSL"
     gene            complement(22259..23776)
                     /locus_tag="KRH82_001203"
     CDS             complement(22259..23776)
                     /locus_tag="KRH82_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8654493.1"
                     /translation="MIINRSKDSSSVNINFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFADNKLAIGNIPKTNVKYTKMFISVNGYDTIMSAYTEASKTTKKKYMIEANLDKFN
                     IIEKGTVTLNIIFEEGFNLINTTFSESMENVKNKVLLVDQYGNKISEKVNNSLFKEVN
                     VIMQKVIQQQENSTTDIENEFKGIERTCSLKGYGDTSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGDYQIELELNFQNIMDEKSVGQDEQKEEISDLSGNGALNGREVKAEFT
                     AYYPSNDPMEGGLYQKMDGKKLVPSNNTCAAPEVLKFKTQIQVKGTGTNIDGKTYTVT
                     DRGGAIKVVNGIYKIDILMSSKKECYNFGRRKGTIIIGDGTGYTNSTGKVKELISIAK
                     GKKGCKYVWGASGPNTFDCSGFTQWCYKKIGINIPRVSRAQGSVGKQVEKKSLQPGDL
                     VFFSSKGPKGTIDHVGILIGNNEFIHSPHTGDVVKISSLKGSYYSKNYVGARRFL"
     gene            complement(24045..24467)
                     /locus_tag="KRH82_001204"
     CDS             complement(24045..24467)
                     /locus_tag="KRH82_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654494.1"
                     /translation="MEMWLRQAEDRFRFPVIPPSISINGKSTINSSNILKVGEIATFG
                     GVALKSINISSFFPNKEYSFCNYKGFPSPYDCVNKIQRWMNEGLILRFTVTETNINME
                     VIIEGFSYEERDGTRDVYFSLDLREYKRLQILRANPKK"
     gene            complement(24467..26797)
                     /locus_tag="KRH82_001205"
     CDS             complement(24467..26797)
                     /locus_tag="KRH82_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654495.1"
                     /translation="MGNVREEGINMYITDNYTPKMNQIISVTEALKRVTVSVSPSVNT
                     MANSIKSSMASASSSINSINSSIKKMTSSIKSLSNSIEKMNGSMNNSGSSNKDFSEGL
                     ETLGRSAENARSKLVRLSQVANSKKGRDTHKNVKAKNNESKNNKSDKPEKIKTVQDIV
                     KRVKTQTVDTSKKIVTGKLPELKNKVFNSNLVMGVKGNNIVQNTLNILNKIKNSKWIS
                     SISVKDLAKNVLIGTLSKLKQFAGRMWTGAISIKDKASSILGGIKDKISDITNGFSIG
                     GAVKKGVDLVGKGQNQKAVLTNVVQRTTGVKDKIEAKSEANNYYNDVIKDIALKSPFD
                     PSEVISMSTKAMTISGGKIDKSKDITQAMVNVRALNMETSSDQDVSAAFVSASKGNMD
                     ALNTLVGENYKTLDDALEGIKEKQNGLANEMAGTIPGLLSSASTYIDMGLNSMIEPFD
                     SILEGGLKKINSFLEKVPSGIGGFSQKVADVMNGKKIAENKQNPIETQVATALGHVPQ
                     SIGNTSQMLVQNIDFTALTNSLLPVVNLVNVLLDSINNKSPVAQGIISIFGTVVTTVF
                     QLIGPVVEAVSPIIMRIFTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIE
                     PILGAFFNILDKVCKIVKDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAG
                     TKAGDSGKAYSSKKGNNAFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNIN
                     IAKLADTIVIREEADIEKITSKLVASIQVAQLGGVL"
     gene            complement(26797..26964)
                     /locus_tag="KRH82_001206"
     CDS             complement(26797..26964)
                     /locus_tag="KRH82_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654496.1"
                     /translation="MYYYWKKKGIRPSLFYTMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGI"
     gene            complement(26991..27437)
                     /locus_tag="KRH82_001207"
     CDS             complement(26991..27437)
                     /locus_tag="KRH82_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBG8654497.1"
                     /translation="MNENGLSKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(27551..27979)
                     /locus_tag="KRH82_001208"
     CDS             complement(27551..27979)
                     /locus_tag="KRH82_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBG8654498.1"
                     /translation="MANMEARNVMSGTWGELWLDGDKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(27993..29057)
                     /locus_tag="KRH82_001209"
     CDS             complement(27993..29057)
                     /locus_tag="KRH82_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBG8654499.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESKVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIINNDIKKVIIDDYIGRVPNSYDNKCILI
                     VAIKEYLEELEKEELIEVGSLVDIDIEAQKQYLKSKNIDISNMKEQEIREANTGSKVF
                     LKAKIKMLDAMEDIDLSIEI"
     gene            complement(29062..29505)
                     /locus_tag="KRH82_001210"
     CDS             complement(29062..29505)
                     /locus_tag="KRH82_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654500.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(29754..30194)
                     /locus_tag="KRH82_001211"
     CDS             complement(29754..30194)
                     /locus_tag="KRH82_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654501.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(30299..30496)
                     /locus_tag="KRH82_001212"
     CDS             complement(30299..30496)
                     /locus_tag="KRH82_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654502.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            30665..30985
                     /locus_tag="KRH82_001213"
     CDS             30665..30985
                     /locus_tag="KRH82_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBG8654503.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            31067..31573
                     /locus_tag="KRH82_001214"
     CDS             31067..31573
                     /locus_tag="KRH82_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654504.1"
                     /translation="MNNLDKLFELASQEEIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            32274..33029
                     /locus_tag="KRH82_001215"
     CDS             32274..33029
                     /locus_tag="KRH82_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBG8654505.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(33172..33600)
                     /locus_tag="KRH82_001216"
     CDS             complement(33172..33600)
                     /locus_tag="KRH82_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBG8654506.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(34021..34221)
                     /locus_tag="KRH82_001217"
     CDS             complement(34021..34221)
                     /locus_tag="KRH82_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBG8654507.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(34404..35573)
                     /locus_tag="KRH82_001218"
     CDS             complement(34404..35573)
                     /locus_tag="KRH82_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBG8654508.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            35809..36630
                     /locus_tag="KRH82_001219"
     CDS             35809..36630
                     /locus_tag="KRH82_001219"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBG8654509.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIHIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(36706..38094)
                     /locus_tag="KRH82_001220"
     CDS             complement(36706..38094)
                     /locus_tag="KRH82_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBG8654510.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(38229..38987)
                     /locus_tag="KRH82_001221"
     CDS             complement(38229..38987)
                     /locus_tag="KRH82_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBG8654511.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVGYLQVIAIAFPLLSGVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     ASIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLICGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(38989..39705)
                     /locus_tag="KRH82_001222"
     CDS             complement(38989..39705)
                     /locus_tag="KRH82_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBG8654512.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(39707..40414)
                     /locus_tag="KRH82_001223"
     CDS             complement(39707..40414)
                     /locus_tag="KRH82_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBG8654513.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEKLFMKVVAENRKRGE"
     gene            complement(40530..41066)
                     /locus_tag="KRH82_001224"
     CDS             complement(40530..41066)
                     /locus_tag="KRH82_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8654514.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(41168..42238)
                     /locus_tag="KRH82_001225"
     CDS             complement(41168..42238)
                     /locus_tag="KRH82_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBG8654515.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHDEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(42231..43313)
                     /locus_tag="KRH82_001226"
     CDS             complement(42231..43313)
                     /locus_tag="KRH82_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBG8654516.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDLNKDINEDSYNNDYYNREEESIKETDEYN
                     DDSINFEAIYKDLEDIENKKGEDKHE"
     gene            complement(43300..43632)
                     /locus_tag="KRH82_001227"
     CDS             complement(43300..43632)
                     /locus_tag="KRH82_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBG8654517.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            43831..44952
                     /locus_tag="KRH82_001228"
     CDS             43831..44952
                     /locus_tag="KRH82_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBG8654518.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(45080..46978)
                     /locus_tag="KRH82_001229"
     CDS             complement(45080..46978)
                     /locus_tag="KRH82_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBG8654519.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            47293..48069
                     /locus_tag="KRH82_001230"
     CDS             47293..48069
                     /locus_tag="KRH82_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBG8654520.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(48161..48913)
                     /gene="xth"
                     /locus_tag="KRH82_001231"
     CDS             complement(48161..48913)
                     /gene="xth"
                     /locus_tag="KRH82_001231"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBG8654521.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(49074..50024)
                     /gene="galT"
                     /locus_tag="KRH82_001232"
     CDS             complement(49074..50024)
                     /gene="galT"
                     /locus_tag="KRH82_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBG8654522.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            50409..51605
                     /locus_tag="KRH82_001233"
     CDS             50409..51605
                     /locus_tag="KRH82_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8654523.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(51940..52392)
                     /locus_tag="KRH82_001234"
     CDS             complement(51940..52392)
                     /locus_tag="KRH82_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8654524.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(52704..54149)
                     /locus_tag="KRH82_001235"
     CDS             complement(52704..54149)
                     /locus_tag="KRH82_001235"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBG8654525.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWTQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIINDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(54293..55201)
                     /locus_tag="KRH82_001236"
     CDS             complement(54293..55201)
                     /locus_tag="KRH82_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8654526.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            55458..56282
                     /locus_tag="KRH82_001237"
     CDS             55458..56282
                     /locus_tag="KRH82_001237"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBG8654527.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            56322..56852
                     /gene="lepB"
                     /locus_tag="KRH82_001238"
     CDS             56322..56852
                     /gene="lepB"
                     /locus_tag="KRH82_001238"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBG8654528.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDENEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(56934..58715)
                     /locus_tag="KRH82_001239"
     CDS             complement(56934..58715)
                     /locus_tag="KRH82_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBG8654529.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
BASE COUNT        19527 a         9653 c         6741 g        22932 t
ORIGIN      
        1 gtatagactt tttttaattt attatttaga tttttaatag attttttaac tatggaggta
       61 tttaaaatat ggaaataaag agatatgaag gaactggaag aatgagtaga actgtagttc
      121 ataacaatac agtttattta tgtggacaaa ctcatgctga aggaggagta attgaacaaa
      181 caactgaagt tttagctaaa atagaagatt tattaaacaa atatggttca gataagcaac
      241 atttgctatc tgttactatt tatttaagag atatgaaaga ctttgaagct atgaactctg
      301 tttgggatgc ttgggttgaa aaagggtttg aacctgctag agcttgtgtt gaagctagac
      361 ttgctagaga gcatttgtta gttgaaatga gcgttgttgc agctacaaaa taatcaattt
      421 agcttatagg aggctatctc aaaacagaga gataagcctc tttttcattg ttgaaatgat
      481 gaaaatatat ttgatttcgt ataaaagaaa gtgtctcacg aactaaaaaa ttcattttga
      541 gacacctcct cactatttaa tctatataaa tttacttatt ctctattggc aatatcaatt
      601 tagatggata tttacctcca tggtaaatcg tattctttgc ttctatatat tcaatactat
      661 tatatccctc tgtcgtgttg ctattttgga aaataaagtt tttagcacta gatgttatat
      721 ctagtctaat tttatgacca actttaaacg tgtttgatat ttttgaagtt ataaccgtaa
      781 acttataaat ctctccttct tccataaact ctgacttata aaaactattt ctaaatctag
      841 cactaagtat accatcagct aatttaattg aatttccatc taaatccacg tccataattt
      901 ttataaccca gtcagtatct ttggcagaac ttgatgcaaa aaactctaac tttatatcac
      961 ctgttacagt aaattcttca ctaaaagcat ctgatgtata acacaacata tcacttcttt
     1021 tttctaaatc tttgtagtta tttggaactc caacttcatt ctctgacata tcaattagtt
     1081 gtactgatgg gtcttttgga ttatatatat aactatcata cttttcttct aaatcattat
     1141 caaatactaa tctaccattt cctaaagatg tgttagcatt tccatcactt attagataca
     1201 tacttttatc tatcttattt attattggcc aattttcttc tgtcttccac ttattagaac
     1261 ctacagagta atactctact ggagcagtcg tatctatgtt attttctata ccttttaagt
     1321 atttatcaaa ccataataga taattataat ccaaatcata tcttaatgaa ctatttccta
     1381 aagaaatacc atttatatct cttaaagtat ttgaattatg catccatgga cctagaatag
     1441 cctttctctt tcctttttca tagtccttta taacatctaa ggcctctgta gttcccatac
     1501 tattatcatc ataccaccca gatacaacca atgcaggtac atttatttta tctttttgta
     1561 aatgccaatc catcaaatcc caatactcat ctttttctac tctctttaac cattcttcca
     1621 gaaattcaat tctatatcca agagcttcaa aaggtatatt ttctattggt cgtatgttta
     1681 aaacatcatc ccaatcatct cttaccattt tgcttctatc aactttattt cttgatacca
     1741 taaatgccca tgcaagcata ccagatacaa aagctcctcc ttttcttggt atatcaataa
     1801 aagggcttcc tgatgttact atactaacta aagctttaag atgcttattg cctgaagatg
     1861 cagctgccca ttggacataa ccaagatatg atgctccaag cattccaact attccacttg
     1921 accattcctg tgatactatc caatttatgg tactatctcc atcttccctc tcatgaatca
     1981 aaggttccca cttaccttct gattcatttc ttcccctaac atcttgtatt acaacagcat
     2041 atcctctttg tacatattta taatatattt ctttatcatt ttcttttcca tatggagttc
     2101 tcataagaat tgtcggtgct tttttggtag aatctacaaa atcagggaga tatacatctg
     2161 tagaaagttt tataccatct ttcatatcaa tcatataatt tccaccaaat cttatagaat
     2221 atatctcttc atttttatga gttttttccc attcttttaa tacagtatac tcttcatatc
     2281 catccataat taatatagta caagtttctc tggataaaca gataaaacct actattttat
     2341 tatctacaat aattatatct agtgggaact ttttgtttct ttgaacccat atatattcat
     2401 taagtttaga atgcgtttct cctaagttat ttataactgt gtctttatct gtgtttacta
     2461 agcttttagt atatacatca aagttattaa ataaagactt taaatctatt tttgtaagat
     2521 ttaaatagta tgtattttct tctttgctta ttggttttaa actttctatt ttatttgtaa
     2581 aaggattcaa cttttcaatt aataaatctc catcaaagat tacatttcca ctgtatagtc
     2641 cagatatgta taatttaaat tttatcaatt aaactccccc ctataatcct agagacatct
     2701 ttattgcata tgccactgat atacctgcat aatttcctaa tactccacca attactccca
     2761 ttacgactgc tacacttaca agcgaattcc actttgcaga agcagctact aaagctgaag
     2821 taggaccatc agcaattgct cctactatag aaagtattac atattgatac tttatcttta
     2881 aaagtctagt tatgcctaaa tggaaaacaa atgaagcaaa aattatgcta aaacagtaaa
     2941 gtgttatagt aaaatttgaa cctaaaaact cttttatatc tactgaaaaa cctattgtac
     3001 ataaaaagaa taatgcaaca aataatccta aatctaaatt tccctttagt ttctttactg
     3061 gctttaattg agcaattata attgaaattg ttgtaactaa aagtattctt gctgcactac
     3121 taaaacttga attgaaatat ccagcaagta ttgttgaaac ttctgtaaca acaaaaccta
     3181 tagccaacat ccaagctata tctttaatac tccattcttt tgactccata aattcttcat
     3241 tttgacaatc ttctaattct gattcttcta catgatatgg ccaaagtttt ttaaacttct
     3301 ttgaattttt taatattgct ggtagagcaa acataaatat caatgttggt actccaatta
     3361 catagtctgc tgcatttgct gctgcaagag tttgtctact tacattaaga cctgttccaa
     3421 tagctgtaag attagcactt ccaccagtgt atgtacctac aaacattcca gcaaccttcc
     3481 aaccttctga tattttttct gcaaatacta atccaaataa aaatgccatg atacttacag
     3541 ttaatacagc tacaaaaatt gcaattaaag gttctcttga taattttgtc atttctttta
     3601 agtcaacact catcaacatt atagtcatag aaactggaat agcatatgtt gaaatagttc
     3661 catataactc agtacttact ggaactactt ttaagtttga aagtattatt cccattatga
     3721 ttattgtaag tgctggtcct aagcttttaa tggctttgta tctttgtaag taaaaaccca
     3781 atgcaatcat tgatgtcatt acagcaagta tactacctgg atttgaaaaa agtgtattca
     3841 tatttaacct ccaaatttat cataagttta cttctattcc taaacctggt ttattgacaa
     3901 gattcataat atctccatcc attacaaatc ctccagatat accttctaat tcttcacaaa
     3961 acataaaact atcaaggtca gcttctgtta tgttcttttt agatgctatt aaatttgctg
     4021 ctgctgttat accaattctc gtttccagca tacatcctaa catacaattt actccacttg
     4081 cctcagctat gttgttgatt tttatagcag gatatattcc acttgatttc atcagcttaa
     4141 tattaaatgt atcaactgca ttctttttta tagccttaat tgcatctatt ggtgaatgta
     4201 atgattcatc tatcataatt tttgtgttac ttttatttct tatgtaagca gtaccatcta
     4261 aatcccaatg tggaagtgct tgttcaattg catcaacatt aaattcttct aactttttga
     4321 tagtatttat actgctattt acgttccatc cttgatttgc atcaattcta attcttatac
     4381 tctctccaac ggcttctcta attaacttta cagcttcaat atcgtcttca ggatttatac
     4441 ctgctttaag cttcaatatc ctaaaacctt cttttactct ttctaaagct tctactgcca
     4501 ttttttctgg cttatctata cttatagtaa tatccgtttg gactttacta tcaaatcctc
     4561 caagaacttt ataaaggggt gcattcataa tttttccttt aatatcatat aaagctatgt
     4621 caatagctgc ttttgcagaa gtattaccta taataattcc atccatgatg gtatgtatgg
     4681 tttcaatatc tagtgggtct ttgcctatta actctttttt aaacataagt aatactgaaa
     4741 gaacattatc caaaacttca cctgtaactg ctgcaagagg tgctgcttcg ccaaatccac
     4801 aatacccttc atcagtttca atttttaaaa ttacactttc tccatattca attactccaa
     4861 atgaaactac tacaggtttt tttaatttaa ttctaagctt ttcaaatttg atatctgtta
     4921 tcttcatatt accctcctta ttttttgaag ttataattca atttttaaaa ttttatactt
     4981 taaattatat tattacttca atatatatgt caagataatt tactgaaaat ttactctttt
     5041 ccaaaatata atgtgataat cttaattcaa ttaatactct tctattaaat ttttttatta
     5101 ttattttctt tgtattaatt taacaataat tcattttcat agacttttat ttggatttaa
     5161 ttaaatttta attgtcaaaa tctactatgt attcttattg ccactacttc tatgttgtgc
     5221 tataattact ttgttttaag cgaatatttt atattaattt tattatttgg aggttcttat
     5281 gctaggtgaa aagatgagaa atataagaaa aagcaagaaa aaaacattaa gtgatgtttc
     5341 caaattgaca gatttatcta taagttatat ctctcaaata gaaagagatg ctattgaacc
     5401 atccttgtct tcattgagaa aaatcgctga agttttagac actcctttat atatgtttat
     5461 ggatgacaat aatactgatg atttagtcat tagaaaagaa gatagagtta tgatgaaatt
     5521 tccaaagagt gaaatgtttt acgagatagt atctccaatg cctacaactg agtttacacc
     5581 ttcaatttta tttgtagagt ttgaacttaa accagaaagt gaggatgcca aagattatat
     5641 atatcatgca tcagaagaaa ttatggtggt aacgagtggt gtggttgata tttgtatggg
     5701 tgaaaaggta gttagattaa atccaggtga ctcaacattt ataaaagcta atgtaccaca
     5761 taaaatcatc aatccaagta aagatacaat agctcgtgga tatggagtta tatcacctcc
     5821 aatttggcca ataaaatcta aataaactca atatgacaca cctacttttt gtagataata
     5881 taatagattt aaatattgct tttattttaa atttgaagta tttatttaaa tttaaaatat
     5941 ttactcaaac taaaaaaata gctatttgac taatctaaac catcttaatt atggtaaata
     6001 gtaaatagct atttgtaagt tatattataa attataataa aaattgtatt tgttaaaatt
     6061 aaattaaact gctatatcat ttaatacttt tgcctttaca actcttatat ttttcatact
     6121 cttgtagata tcttgaatct tatcttcttg ctctctcaat agtctatgtg cttcatatat
     6181 atctacaagt tcaaatttta ctacatcatt tggctttgct tgtgctaact tatacaaatc
     6241 tacacttata acgttcccta tcttagtata gccaccacta gtctgtctat ctgataacat
     6301 tataatcggt tttccatgac caggtacttg tatagctcca taagaaatac catcagatat
     6361 aatatctgct ccattaaggt gctttatact ctctccatct agtctacaac ccattctatc
     6421 tatttcattc gtaactttgt atttatttga taaaaatttc tctacttcac cgttagaaaa
     6481 agcatcaaat tgaggacctt ttacaattct tagtacgatt tctgaactat aagttggaat
     6541 atattttgaa cttaattttt tatttattgt aaaatctttt tcctgaataa aagtatttat
     6601 ataatctcct tttttaagtg ctctaccttc aaatccacca attttagctc ttgtataagt
     6661 tgacttactt cccattgcaa gtggaacatc tattccacca gctattgaca cataggctct
     6721 agcacctgat ttcacacctc taaatgataa tacatcacct ggatttattt gatatgacct
     6781 ccagttttga atttcttttc catttatttt agcccctaaa tctcccccag ttactgctat
     6841 ttgcgtatat tcatcaaagg taattgtagg acctaacatt aaaacttcta aagaagcctc
     6901 atcttcagaa tttcctacta atatatttcc tactctatgt gcatactcat ccattgctcc
     6961 acatccagat acaccatatt gaccatagcc aactctgcct ctgtcttgta ttaatgtttg
     7021 gaaacctcct aattcaactt tgaatcccat atataccact ccctgtacta taacgatatt
     7081 taaatactta agttattttt ttcgatttct ataaattcat ctaatgttat tggaacaaat
     7141 tttataaaat ctccagctct aagcaaaatc tgttcttctc tattttcatc atataatttt
     7201 aaaggtgtcc taccaattat ttgccatcca cccggactat caataggata tacaccagtc
     7261 tgggaacctg ctattccaac actcccacca taaattttag tccttggcac ttctaatcta
     7321 ggtgtagcta ttctttcatc cataccacct agatatggaa atccaggagt aaaccctagc
     7381 atatatatca agtactctct acttgtgtgt atttttataa cttcatctac agtgagatta
     7441 ttgtagcttg caacgttttt aatatctata ccaaaaacct catcataaca tactggaatc
     7501 tcatgtattt taggttttgg taatactata ctttccaaat tatcttctat tttttttaaa
     7561 ttctcaatca aactatcaaa atctatttct aatggattat aacttatcat aagtgaccta
     7621 tatgttggta ccatttctgt tacaatacct ttaagattcg atatttctat tgctctcata
     7681 aatgaaatta cttttttgtt tatatcttct gatatctcat ttccaaattc agcaaccact
     7741 gccttatccc ctgatatcaa gtatctagtt tccataaatg tcacctcttc taagttaagc
     7801 aaataaagca cctaggctgc taagagaagt tattcctgta tatgcagata ttaaaactac
     7861 tattaatcca aatattaaaa gccatgtagg atgcttgtaa tctccaacaa tatcttttct
     7921 tttagatgct ataagcataa ttcctaatgt gattggaagt atcaatccat ttaaagctcc
     7981 tgctaaaatt aataaagtag ctggttttcc tataaatgcc attataagtg ttgatattgc
     8041 tataaatgct attataaaat atttttcata tttatctata aaaggattta gtgtctttaa
     8101 gaaagaaact gatgtataag cagctcctat aactgatgta attgcagcag accataatac
     8161 aagtccaaag aatttatatc ctattgctcc tgcactaaat ttaaaagctg aagcagctgg
     8221 attttctggg tcaagttgaa gaccttttga aaccactgcc agtattgcta aaaataaaag
     8281 aactctcatc attgtggcaa ctaatatacc caaaagagaa gatttagtta tttcttttat
     8341 attttcttct cctgttattc caccgtctat taatctatgt cctccagcaa aagttatata
     8401 acctccaaca cttcctccaa gtagagttat tattgggaat atcagtcctt ttggattttc
     8461 tggttttacc attcttgata ctgcctctcc aacaggagga tgatttgata ttgctacata
     8521 tccaactata attatcattc ctaatgctaa aaatttagtt atcttatcga ctagagaatt
     8581 tgaatttttt gacataaata caaatatggc tattaatcca cttaatacag ttcctaatgt
     8641 catattcata ttaaacatta cattcatacc aagtgcagct ccaccaacat ttcctatatt
     8701 aaaagctaat cctccaagag ctactaaaaa agctactaaa taacctaatc ctggtattat
     8761 tttatttgct atatcctgac ctctaagtcc tgatacacca attactctcc atacatttac
     8821 ttgagcccct ataaaaagga ttgttgtaat taaaattaca aatgaaaaat tcggtccaaa
     8881 atcttgggta aattgtgcag tctgagttaa aaaccctggt ccaattgctg atgttgccat
     8941 tataaatgca gcccctataa gtgctccaac atctttttta tttttagttt tatctgtaat
     9001 attttttgta ctcatatttt atctccccct catgttatca gtcttatact atgttctctg
     9061 acgaacaaac ttctatgttt tctaatggac aaacttctat actttctaat tcaaaacgct
     9121 ttcttatttc tttgacaaac tctattgctt ttggattgtc cccatgtaca catatagaat
     9181 ctgctttgat atgtataact tcacctgtta aagtttctac agttccttct tttaccatcc
     9241 taacaaccct atctattgca tgttttgtat catgtataac tgctccttct acacttcttg
     9301 gaaccaaaaa accattatta tcataagctc tatctgcaaa tacttcattt gcaaacctaa
     9361 gtccaatttc tttagcagaa tttatcattt cactattata tagccccaac agtataatat
     9421 ctttatcgac ttcatatata gcttcacaaa tccccatagc taactcttta tctttagctg
     9481 ccatattgta taatgctcca tgtggtttta catgttgtat attacatcca tttgaacttg
     9541 caaatgccat taaagcaccc aattgatatt ttgtataatc tttagcttcc tgctttgtta
     9601 ttttcatctc acgtcttcca aatcctatta aatctaggaa acctggatgt gcgcctattt
     9661 tcactccatt ttttttagct agctgtactg ttttttccat atgactaggg tcacctgcat
     9721 gaaacccaca agctatattg gctgatgaaa tatattttaa aacttcttca tctaaaccaa
     9781 tcttatacgt tccaaaactt tctcctaaat cactatttaa atctacttta tacaatttat
     9841 gacccctcct cgctaacatt ttgatagaat aagtagtttt aatttttaaa ttttgtttat
     9901 tttatatatt gcatgaaata ttttatcact tgtattcaat tttatttttg caactattct
     9961 attgcattta attaatataa ttttaccatt taaggaatat ttttgcaatt attttaattg
    10021 aacattcatt tgtatttctt tttcaaaaaa tctttttacc attttttagt taataattaa
    10081 ttattttcac ttaaaataag ggccttaacc ttcattttta aagtattttt catttttaat
    10141 cactttatat gcaagacaga atcatttttc ttcattcatt tgtttctttc atctatataa
    10201 ttatcattct ttgtaagtaa aatatcttta tatttttata attaattctt tatatagttt
    10261 taagtataat aaaatcatgt atactaaatg catgttaaaa tattatttta aaacatgcac
    10321 aatatttgta catattgtag acatataaac ctataaatta tacaatagta ttgttaagat
    10381 tatatatttt tttaacataa attttgtatt gggggaaaaa caatggataa aaactatacg
    10441 atgccaatat accaaaaaat agcgttggat attgcaaata aaatatacac gggtgaaata
    10501 caagaggatt cagtactatt tggacgctct gttttggctg gtaaatacaa tgtatctcca
    10561 gaaacgataa gaagagctgt caaaatttta gaggacattg gcgttgttaa aagcataaag
    10621 ggtaaaggtg ttattgtact atctccagac aaagcttctt cttttataaa aaaatataga
    10681 gatattacaa atatatcatc atataaatca acactttata atttaataga tactaaatct
    10741 aatttagaaa atgaaatatt agatactata aataaaattt tagactattc taacagactt
    10801 gaaataatca atcctttagt gcccgttcag ttcaccataa attctaattg caaatatatt
    10861 ggtcaaacag ctgcacaaac taaattttgg caaaatacag gtgctacaat agttgcaatt
    10921 aaaagaggtg aagaacttat aatatctcct ggaccatata ttgaattttt agaaggagac
    10981 attctcttag tagttggtga ccaacacatt tacaattcta taccaatgtt tttatatgaa
    11041 aacgaaaaat aaattatata atttagtgtg attatataaa aatgcaagat taacaacaaa
    11101 aaaagagctt catattttac ataaagctct ttttaaattc aaataaattt aactttgatt
    11161 aatttttaaa tatccaattc atcttctttt tcccagctta aagctctcga tacagctttt
    11221 ttccatcctt tatataattt acatctcttc tcttcactca tatttggatt aaactctttt
    11281 tctactgacc actttgaagt aatttcattt cttccaatat agaatccaac agacaaccct
    11341 gctaaataag cagctcctaa agctgtagtt tctactattt tgggtctatc tatatctaca
    11401 tttaatatat ctgattgaaa ttgcattaaa aaattattat tacttgctcc accatcaact
    11461 tttaatgatt ttagttttaa ttttgaatcg ttttgcattg cttctaaaac atcctttgtc
    11521 tgataagcaa ttgattccaa tgtggctctt actatatgtt ctttttttgc tcctcttgta
    11581 agtcctaaaa ttgaacccct agcatacata tcccaatatg gagctccaag acctgtaaat
    11641 gctggcacta catatacacc attagtatcc tctaccctat ttgcatacat ttcactatct
    11701 tttgcagatt caattatctt taattcatct ctaagccatt gaacagatgc tcctccaata
    11761 aatatacttc cttctaatgc atatgttact tttccatcaa ctccccaagc aattgttgta
    11821 agtaacccat gcttagattt aactatgtta ctgcctgtat tcataagcaa gaaacaaccc
    11881 gttccataag tattttttgc agtaccttct tcaacacaat tttgaccaaa taatgctgct
    11941 tgttggtctc cagcacatcc cgcaataggt attttagctc ctgataacat gcgctcatct
    12001 gtatgaccat aaacatagct agaaggtttt actaatggca acatgcttat tggtatgtcc
    12061 aattctcgta atatatcctc atcccattct aaatcattta tattgtacat cattgttcta
    12121 gatgcatttg agtaatctgt tacatgtact tttccacgag ttaaattcca tattaaccat
    12181 gtatctatag ttccaaataa taactctcct tgttctgctt tttccctagc tccttctaca
    12241 ttatctaata tccattttac ttttgttgct gaaaagtatg catctattaa aagacctgtt
    12301 ttttctttta ttgattcttc caatccttta tttttaagtt catcacatat ttctgacgtt
    12361 ctcctacact gccatactat tgcgttataa ataggtttac cagtatacct actccaaaca
    12421 accgtagtct ctctttgatt agttatccct attgaagcaa tttcttctgg tcttatacct
    12481 gctgtttcta taacttctct cattacccca ctttgtgacc cccatatttc cataggatca
    12541 tgctctaccc atccagcttt tggataaatt tgattgaact ctttttgtgc aattttcact
    12601 atttcgcctt ttttattaaa tagtatagct cttgaactgg ttgttccttg gtctaatgcc
    12661 attacatact tcttttccat caccatattc tccttatcat ataatattta atttattaaa
    12721 aagaaaaatt taatatcaca tatttcaata aataatcata cttaagtaca aatttaatat
    12781 aatagatatt tagtaagaag acacttattt tctatcatat ctatataata atattataca
    12841 ttatagctta catattgatt aataaatttt aaaggagtat aataaacagt gttcataata
    12901 attttaataa aagaggtggt aatatgccaa agattttaga aaatgtaaaa gaagatatat
    12961 taaaagtgtc tcgggatatg attttagaag aagattactc gtatattagc ataaggaaaa
    13021 tagctcaaag gtgtggtata agtgcaggta cagtgtataa ttactttaat tcaaaacaag
    13081 aaataataga atatatcaca aaatctgaat gggatttatt gataaggcga attgaatact
    13141 ccaataaaaa cactgaagat tacataaaaa aactaaacat tatttttact gaaataagaa
    13201 attttataaa caaagttcat aatatccaat acaatgactt tttaaacact tttgaaacag
    13261 agagattttt tgaaatgaaa aaacacaaag acgactttca tgaacagctt tcaaataaag
    13321 tatatgaagc tttagaaaaa gaaagttttt ttaataatga caaattagta tgcaatatca
    13381 taataaaaat gtttttttca tattcaacat atcttcatat agaatttgaa gatttaaaac
    13441 cctatattga aaaattaata cattaaggtg gtgtttacct tgaatcataa tactagtatt
    13501 aagaacaagg acagtaatcc aaaaatattt ttagtactta cactttatct attaggtata
    13561 tttatgggag ctattgatac tggaatagta tcaccagcaa gaacgattat acaaaatagc
    13621 cttggagtaa atgaaaaaac gggaatttgg atgattacca tatacacatt aacatacgct
    13681 tctgtaattc ctatctctgg aaaattagca gataaaatag gaagaaaata tgtgtatcta
    13741 gttagtatat ttctatttgg tagtggttca ttaatatgtg gattatcatc actattttcc
    13801 aatttctata ttttattaat tggtcgtgtt attcaagcaa ttggtggtgg tggaatcatg
    13861 ccaattgcta cagcagaatt tggaactacc ttcccagaaa ataaaagagg catggcttta
    13921 ggtttagttg gggcaacata tggtattgcc aatattttag gttcaagcat tggtagcaca
    13981 attctaagta tctttggaac tcaaaattgg aagtggctat tttttgtaaa tcttccaatt
    14041 tgtttaatca tacttattgg tggagttttc tgtattaaaa acaataagtc tgaatctaaa
    14101 gaaaaaatag ataagcttgg tacattgatg ttgatatgta taatcgtatc actattatat
    14161 ggtcttatga atatagactt ttttaatttt aaaaattcta tacaagatat atcagtttat
    14221 ccatacttat tgacatttat tgtacttata cctattttca tatttattga aaatagagct
    14281 aaagacccta ttttaagctt tgaatatttt ttaaatccga gaatattgat agtacttatt
    14341 ttatctttaa ttgttggtat tggaatgatg ggtatggtat tcgttccaca gtatgctgaa
    14401 aatgcattaa agataaatgc tggttctggg ggatattttg tagctatatt gggattattt
    14461 gcaggtattg ctgctccttt aagcggaaga cttattgaca aatttggggc aaaaaaaata
    14521 ctattactag gattttctgt atctatgata ggttctcttt acctagtttt aattgctcta
    14581 aaaaccaata ctgtatttag tgtatgtgta agtttaatat ttatgggatt aggaatggga
    14641 tttactatgg gaactcctct aaactatatg atgttatcaa atacaagatt agaagaatct
    14701 aattcagcac ttgcaacatt atccttgata cgctcaattg gtacttcaat ttctccagct
    14761 ataatgattg gatttatagc acatgcagga ttatctgtgc aagataatat tatggactta
    14821 gttggaaagc cctcaactcc taaaatagtt caacttgaag aacttgaaaa catgatagat
    14881 gacttaaaat cagaccctga aatggcaaaa aatttaaaaa atgtctctat cccaaatatg
    14941 aatgatactt caaatataaa tatggacatg acaggtggca aacttccaaa atccttactt
    15001 aataaagttc agtcagcaga tacaaccaac attaccaata taacaaaaga aatatcaaca
    15061 acaatgtttg atgaaaaagt tccatctata attactaaaa tacagaaaaa tgtacaaaaa
    15121 ggaatagatg gaacacaaag tggaataaac ggtattgaag atggtgaaaa taaactaaat
    15181 agtggtatta aaggagttca aactggtatt gacaatatgg taaaagctag agctggtatt
    15241 aatcaaggaa tagatggtgt aaaaaaaggt attgctggtg ttgacaaagg tataaaaggt
    15301 atggaacaag gtcttgaaaa acaagatgag gccatcaagg aacttacaac tgcttataat
    15361 aaaataccta ctacagaaaa aactcctact gataacgaaa ataactcaaa tgaacaaaac
    15421 cagagtaata ccagtaattc tgaatcagat gacactaaga atgattctac agaaaataag
    15481 aataacaatt ccagcgagaa taaaccaaat gtaaatgaac aaaaagaaag tttaaatgct
    15541 caaatacagc aactaaaaaa gacaagagat gacttaaata caaagttaca aaaaaataaa
    15601 actcaaaaga acgaattaag taaaaaacta agatcaatgg aatctcaaaa gaaagagcta
    15661 caaagcaagt taaataattc tataagccaa aagaaagaca tggaaaaaag ccttgataca
    15721 atgcaacagc aaaaaaaatc actccaagca gttttagcaa agacacaaga ggtaaaaact
    15781 gaaataccaa aggcttttga taaatcaaaa ttggattata taaattccat agaaaataat
    15841 agaacaaaaa tagaaaatac actacaatct actctaaact caggatttaa acagatgtat
    15901 ataacagtat tctgtgtaaa tctactagca tttataatat tattgttcta taaagaaaat
    15961 aaaactagat aaaagagtgt tatagtatta tattgtaaat ttatcttatt cttaaatatt
    16021 ttattctaaa gaataaattc ataaaatttt tgtaattgat taatataaat tacaatataa
    16081 tactattttt ctcttaatct ttttctcttt tacagacaat caaaaagcaa tcttagttta
    16141 tcgaaataaa tttatacaat ctattcatac acccctttac atttttataa caattaaacc
    16201 tattgttata tatacaaatc aaaataaacc atatattttc aactataata tgttaaaatc
    16261 atattatgag catattaatt taagcaaaat gtcatttaga ctttaattta gtagttttat
    16321 attataaatt tatatatttt taattttaaa tgtcatttag acattactca taaaaagaaa
    16381 ggagtgtatt ttgtggatac tttaggaaaa agaattgctt atttgagaaa ctccaaaaaa
    16441 cttactcagc gcaaacttat ggatatttta aaatttgaaa acttaggcaa gtatgaaaca
    16501 ggagatagaa aacctaattg tgatatacta atgtcaatag ctgattattt taatgttacg
    16561 actgactggc ttctctatgg taaagagaag gtaaatgtca atagtagtgt aaaagaagat
    16621 aaagaagatt acttacatgt tactaatgat gaaatgatga tattaaatct atacagacaa
    16681 ctaaacgaac gtgataaaat aaaaatagaa ggaatacttg aacttaagat atctgaatat
    16741 aaagacttaa aaaagcattc ctctaataat aatgaagata aaatggttta aacatacata
    16801 atttgatacg attttacatc atctattaac cttctttttt tgtagtatat tactaaaata
    16861 tggatattgg attatttaaa aacaagtata gtctaatttc aagcacattt ataatattta
    16921 gattatctta tccatatttt agtttaagta ctttgaaaaa tataatacat ctctatgtat
    16981 aacttagatt cctaagaaat gcattactca tgtttttaat tcttccaaca tctttctata
    17041 cacaattgta catccttcat aattcccctc tttaagaagg attgaacatg tactagaata
    17101 tttagttaaa gtatttaatc tttccatatt taagcttttt atattactga gtgctgtaat
    17161 aaaatcatca attgctctac aacactctat aaccccatct gaatccaatt tacacacaag
    17221 aatattcacc tactttatat actatttatt aatcatcttc tgaatattct atattaagta
    17281 attgataaat tgatgattta tattttttac ctgttcttct tccatttaaa atagctgaca
    17341 aatagttttc attaacacct attttcttcg ctaattccct ttgagtcata tttaattcaa
    17401 taagtctttg cttgacttgc actcccaaaa aaggtatcca tttttttcga gcatccattt
    17461 atcaacttcc tttctaagtg atttatattt acttttatat tattttagct tacacacccc
    17521 ctctatttag tatatatttt taatatgtac acatattaag tatataaatt tatttaatac
    17581 taaataagat tttttgatta ctttgtgcta aaattaggat gtaaattcgt atcattaagt
    17641 taattataaa gtcattttga ccttaagtca atggttttta tgtcattttg acctttaatt
    17701 tgaaactatt tacatcttaa aaagtctttt tgacattaat tgaatggaga gtgtttatgg
    17761 atactttagg agaaagaatt gtttatttga gaaaagcaaa aaaccttaaa caatatgaac
    17821 tagaagaaat gttgggctgt gacaacttaa gtaaatttga gagaaacatt agaaaaccaa
    17881 attatgaaat attaaaatct atagctgaga tatttaatgt ttcagtagac tggctattaa
    17941 atggagataa tctatcacat aaatcagatt taatttgcga ttcctcctca aactatccac
    18001 ttaatagcat aaactctaat gaaataaaac ttttaaacaa ctttagaaag ttaaatgatt
    18061 atgataaagc caaaatagaa ggtatgattg aattaaaact tcatgaatat gaaaaagaga
    18121 aggatttagg aaaaattgag tataacaaaa ataaagatga gaaaatagat aaataatttt
    18181 tatgttgctt ttgatacgat tttacatcat ttctttgttc taatattttt atttcattta
    18241 ttttcttttt tataatttta tgataaaata attagtatat tttgctttac ttgaatgtaa
    18301 ttatttatac aaaagtcaaa cataatataa atgtagtaaa tttttagttt caagtaatat
    18361 ctcgttatta taactaaata tttattaaaa ttaggaggat aaaatgggct taagagacaa
    18421 attcgcgcaa tcatttgcta gatcaaaaac tatgagtggc cctgagaaaa aggctaatga
    18481 aataatgggt aaattgcttc ttaagaaagc tatattacct atcgttttaa tgttcgtgat
    18541 aataatcgct ggagctatgc ttaaaatcaa ttcttgggtt acacttggca taaatttagt
    18601 tattgctgtt ggtgctttct tctacataag aaattctagt aaaaagtatc agaactttaa
    18661 accttatgtt ggcaatttga ttagtttaga gaaaaaaggt aaaaaagagt acgttgctat
    18721 tataaaacaa ggtaagttac cagttaagtt acaaatagct tatggtggtg aagaccttga
    18781 acatgttaag aaaaatcaaa tggttcaaat aagttataat ccagatgcta aaatagctat
    18841 tttggttaat agacaataat ttaataaaaa aaaagagttg tcttaaaatt gatttttcac
    18901 aatcaagttt aagctcaact ccttttttaa tttttatatg ttatttttat tactttttta
    18961 ttaatatctc taagttataa aattccagtc tatacaatat tccatttttt atttttatat
    19021 tggtaacata tcttttatat cattaatcaa actaattcta gcagtattta cactagtaca
    19081 taactcatct atagctcctt gaacatttgt agcagcaagt ttacttactg tattatcata
    19141 acttgttttc tctgctgttg tttctatgct atcaagacct tcttttacct cattgactgc
    19201 atttacaaga cttgttttat cagttgtatt gagtagagtt gtatctccta ttttactagt
    19261 gacatctgtc ttagtattat ctattttagt atttaactct attttagtag tttctatacc
    19321 acttgttaat gttattttag ttgtatctat ttttttatct aactcttgta tatcttttaa
    19381 agttgccaag atgacagttg ggtcaacttt taaatttaca cttgaagtat tagaaactac
    19441 caatataatt cttataatta aatcttttac acttccagaa tcagcagttg gtttataagt
    19501 ttctggatat ttagatatag ctataagctt attttctgaa tcaaatatac caacttctct
    19561 tatcataaaa ccgccaatac tacctggtat tacagtttct ataactatcc agttagagtt
    19621 gtcatcatct atttttacat tacttatatt gccttcccag acaacttctt taagagatgt
    19681 ttgttcttct gtaggactat actcacttcc tccaccatct ccaagttgta gtttaactaa
    19741 atctactttt ttaccaagag cagttgcatt tgcaatagat gctttacctg ctttagttaa
    19801 aagtgtatag tatttttgtt ctgccaattt atatcgcctc ctgtttagga tataagatta
    19861 ctttttccat acttctatca tttcctgtag aaatggttat ctctccaaat atctctatat
    19921 ttgatggtgt ccacggatat acagtaacag tttctcctgt atttatagca gttccacaaa
    19981 atagttcatt tttatttaac aaaatcattt taaatttatg ttccagatga catggcttta
    20041 cattttctaa tactttatcc aactctacaa tagaattata actacaatta ttaactataa
    20101 actctaatat aaatataaat tcattgctga gtactgttac ttcaacatca gtctttgtat
    20161 aagcttcaca aatgtttttt ataaccttca atttagttgt tcctaaactt ctcattttag
    20221 cctttatatt gcttcttcta gtctcataat ttaaatcttc attattttga atacacaata
    20281 tactttccca catatcaaga ccccatgtgg atgtattgac aaacatttga tttatagtat
    20341 catctatatt ttcttttaat gaagataatt cactatcata agaatcttgt attgcttcaa
    20401 ccatataatt tttataaaat gatggtagtt tatcaattaa tttcattaaa cctccacctc
    20461 actaaaatct aaagttgtaa cactaggtat tttatcatct tcaatagtta tattgtctgt
    20521 tgagttattg acaagtaaat tgcttaaatc atggactcca gaagtactta ttagaatccc
    20581 catgattttc gtgtatacaa tttctcctgt tatacttcta aaatattgat ttatattttc
    20641 tataaaacta ttttttacca tatctaaggt atatccactt tctagctcca tagatgcact
    20701 tatagttata tttagtggga ttggagtagt tactgttagt gtagctccta ttggcatttc
    20761 ttcctcaata tgttctctac acttagttat tatttcttct tcaaccgctt gattattttg
    20821 tccaaacaat aaaaccttaa ctgtccctgc tccattccat cttggatata cttttgcatt
    20881 atatacacca tcaacttcta aagcccattc ttcataatgt gctttattcc cacttgttgc
    20941 ttgatttttt tgtactctaa aaaacctttc tctcagttct tcatcagttt caatttctgt
    21001 accacctgaa aatttattta tatttgttat cttttcaatt ccaaatatat tatcatttac
    21061 cttaaattca caatcagatg gtaaattata tctagttcca atttctagtg cttcgactgg
    21121 acttatattt ccttcttcac caccaatgac aatatccttt attaccacaa atgataaatc
    21181 tttataggat ataattgttc catttgatat ttcaacacca ttttcaccta taaattctac
    21241 ttctccagta gcctcagtac ccaattttct atatacacca aattcattca ctctcttatc
    21301 taataattga ttataagtgt cttcaataaa agccatttta tatatgttag aaagttcaac
    21361 atacattttt gaaagttcaa aggtatttcc agaaaccata tcatttagaa aagaaccttc
    21421 tcctttatac acatctaaat ttatattttt aagggttcta ttttttattg tttcataagt
    21481 ttgattacta tacatttatt tccacctccc catagatagt ggatattttt atatatgcac
    21541 ctaatatatc ttttttaaaa ttagtattta ctacatctac ttgtaaaata tatggattca
    21601 taagcaaagc ttcttttata tatcgagatg cttcactttc tgtaagacct ttactatatt
    21661 tttgacctat taaatcagtc aactctgttc cataatcatt tgagtaaatc tcatgttcat
    21721 ttttatttgt ttttatacac ttatataccc aaacttttat agcttcattt ttttcaataa
    21781 tcttaaaatc tccattttct actattggtt catctttttc aaagttccat gctacttcac
    21841 gaaataaccc taattcctct tttttaggaa tttcatagtc ctctggaaca cctataaaag
    21901 gaaatattgt gttagacatt ataaactcac caacttactt attattgcaa atttttctcc
    21961 tactttaaac ataataactg tgtcaccttt atctagttga ttagtgagag attcatttaa
    22021 ttcatgagta tggttattag actgtgttat tataaagctt tttgttgctc tatcaaacaa
    22081 ccaattatct ataagtaaat tgtctttatc taaaactata ttattcattg atacttttaa
    22141 atctggcaat ttatttatta tttttccaac aaaaaaggaa ggcttattat aatatttccc
    22201 ttccttcctt attattccta taaattcatt tattgaatta gccactatac cacctctctt
    22261 ataaaaatct tcttgctcct acataattct tagaataata gcttcctttt agactagata
    22321 ttttaaccac atcaccagta tgtggagaat gtataaattc attgttccca attaatatac
    22381 caacatgatc tatagttcct ttaggtcctt ttgaggaaaa gaaaactaaa tctcctggtt
    22441 gcaaactttt cttttctact tgctttccta cacttccttg tgctctggat actctaggaa
    22501 tattaattcc tattttttta taacaccact gagtaaaccc actgcaatca aaagtatttg
    22561 gtccacttgc tccccacaca tatttacatc cttttttacc cttagctatg ctaattaatt
    22621 cttttacctt tcctgtggaa tttgtatatc ctgttccatc tccaataatt atagtacctt
    22681 ttcttcttcc aaaattataa cattcttttt tactagacat taatatatct attttataaa
    22741 taccattaac taccttaata gctcctcccc tatctgttac tgtatatgtt tttccatcta
    22801 tatttgtacc agtgcctttt acttgtattt gtgttttaaa cttaagcact tcaggagcag
    22861 cacaagtatt gttagatggt acaagctttt tgccatccat cttttgatat aagccacctt
    22921 ccattggatc atttgatgga taatatgctg taaattctgc ttttacttct cttccattta
    22981 atgctccatt accacttaaa tctgaaattt cttctttttg ttcatcttgc cctacagatt
    23041 tttcatccat tatattttga aaattgagtt ctaattcaat ctgataatct ccattttgcc
    23101 atgtatgttt atctgtatct atatagaata atcctaccaa ttttgtatac gaatctttta
    23161 cctttacacc tctaccagtt atacaacttg tatctccata tccttttaga gaacacgttc
    23221 tttcaattcc tttaaactcg ttttctatgt ctgttgtact attttcctgt tgttgtatga
    23281 ctttctgcat tatcacattt acttctttaa ataaagaatt attaactttc tcactaattt
    23341 tatttccata ttggtcaact aataatactt tattctttac attttccata ctttcagaaa
    23401 aagtcgtatt gataagatta aatccttctt caaagatgat atttaatgta acagttcctt
    23461 tctcaataat attaaattta tcaagattag cctctatcat atactttttc tttgtagttt
    23521 tgcttgcttc tgtgtaagca ctcattatag tatcatatcc gtttacagat ataaacattt
    23581 tagtatattt tacattagtc tttggtatgt ttccaattgc aagtttgtta tctgcaaata
    23641 cttgctttgc aatatcctct actaacttat ccttaaaatt ataggacact tcactttgta
    23701 aaagtaaaaa tcccatatcc ttggctgtaa aattaatatt aacactgctt gaatctttag
    23761 atctgttaat tatcatccct ctaaaaagtt ctttttcatc tacataaaag caaactgtgc
    23821 ttgctattgg aatatcaatt tgttgaaaat taatatcaga agctgactgt actatagaaa
    23881 attctaatgt tcttgaagga gacttataat ctccagacca agaaactgaa tctactatat
    23941 tacttatatc atagatattt ccgtttttta tgtgtaccca aatctttata ataaaaaatc
    24001 acctaccttt ttctctgatt ttgagtaatt ttttataaat tgtactactt tttagggttt
    24061 gcccttagta tttgaagtct cttatattct cttaaatcta gtgaaaagta cacatctctt
    24121 gtaccatctc tttcttcata actaaaacct tctattatca cttccatatt tatatttgtt
    24181 tctgtaactg taaatctcaa tattaaacct tcattcatcc atctttgaat tttatttaca
    24241 caatcataag gggatggaaa tcctttataa ttacaaaaag aatattcttt atttgggaaa
    24301 aaactagata tattaatact tttaagagct acgcctccaa aagttgctat ttctccaact
    24361 ttaagtatat ttgatgaatt tatagttgat tttccattta tacttattga tggtggtata
    24421 actggaaatc taaatctatc ttcagcttgt ctaagccaca tttccattat aagacacccc
    24481 ctaactgtgc cacttggata cttgcaacta attttgatgt tatcttttct atatcagctt
    24541 cttctctaat cactattgta tcagctaact tagctatgtt tatatttcca ccattttttc
    24601 tgcttctata ttgatttgct tcttgtttag ttaaaaccat ttcaccttca tgaagtctgg
    24661 tttgatagtc attataagga acatagttca atccaaatgc attattacct ttcttacttg
    24721 aataagcttt accagaatca ccagcctttg ttccagcata tggattatct ttgtaatttt
    24781 ttttactctt ttccactaga tttaaaactg ttcctgtgat gcttccattt tttatcttat
    24841 taatcatagt ttgccaccat ttgcatatat ctttaactat tttacatact ttatctaata
    24901 tgttaaaaaa agctcccaat attggctcta taattttcca tccagtttcc aacagaggtc
    24961 ctaaggtctc ccatacagtt ttccaaataa cacccagtgt ctctataaaa ttgtttattt
    25021 gaggtgcgta ttctcccaaa aaggtaaaaa ttctcataat aattggacta acagcttcta
    25081 caacaggtcc aatcagttga aaaactgttg ttactacagt cccaaatata cttattatac
    25141 cttgtgctac tggtgatttg ttatttatac tatctaataa tacattaact agatttacta
    25201 caggaagtaa tgaatttgtt aatgcagtaa aatcaatatt ttgaacaagc atctgacttg
    25261 tattacctat tgattgtggt acatgtccta atgctgtagc tacctgagtt tcaattggat
    25321 tttgtttatt ttcagcaatt tttttcccat tcattacatc tgcaactttt tgagaaaaac
    25381 cacctattcc gcttggcact ttttccaaaa atgaatttat tttttttaat ccaccttcta
    25441 atatgctgtc aaaaggttca atcatactgt ttaaccccat atcaatatac gtggatgcac
    25501 tagataataa gcctggaatg gtaccagcca tttcattagc taatccattt tgcttctctt
    25561 ttatcccctc aagtgcatca tcaagtgttt tataattttc tccaactaaa gtattaagag
    25621 catccatatt accttttgat gcacttacaa aagctgctga tacatcttga tcactactag
    25681 tttccatatt taaagctctg acatttacca tagcctgagt tatatctttc gatttatcaa
    25741 tcttacctcc actaatcgtc attgccttag tactcattga aataacttca ctaggatcaa
    25801 aagggctttt tagtgctata tcttttatta catcattata ataattatta gcttcagatt
    25861 tagcttcaat cttatcctta actcctgtag ttctttgaac aacattagtt aaaacagctt
    25921 tttgattttg accttttcct actaaatcta cacctttttt tacagctcct cctattgaaa
    25981 atccattagt aatatcagat attttatctt ttattcctcc tagtatacta ctagctttat
    26041 cttttattga aatagctcca gtccacattc ttccagcaaa ttgttttaat tttgatagtg
    26101 ttcctattaa aacattttta gctaaatctt taactgaaat agaactaatc catttactat
    26161 ttttaatttt atttaatata tttaaagtgt tttgaacaat attatttcct ttaacaccca
    26221 ttactaaatt gctattaaaa actttatttt taagttcagg taatttacca gtaactattt
    26281 ttttagaagt atctactgtc tgagttttaa ctcgcttaac aatatcttgt acagttttta
    26341 ttttttcagg tttatcgctt ttattatttt tagattcatt attttttgct tttacatttt
    26401 tatgtgtatc tcttcctttt ttactatttg ctacttgtga taatctaact aacttacttc
    26461 tagcattttc tgcacttctt ccaagagttt ctaagccttc actaaaatct ttatttgatg
    26521 aacctgaatt attcatactt ccattcattt tttctataga attacttaaa ctttttatac
    26581 tactagtcat tttttttatt gaagaattta tactatttat actactactt gcactagcca
    26641 tagaactctt aatactatta gccattgtat ttactgaagg agaaacagat acagtaactc
    26701 ttttaagggc ttccgttact gatataattt gattcatctt tggagtgtaa ttatctgtaa
    26761 tatacatatt tataccttct tctcttacat ttcccactat ataccacctc ctgtcaaagg
    26821 acaaactcca tatccatgct tcattttttc aacttcttct tcaatttcta aggcgaaaaa
    26881 agcttcaata agctttaatt cgcctttatc cattgtataa aaaagggacg gtcttatacc
    26941 ttttttcttc caataatagt acattatcgt agtcttggta tccgtcccta ttagtttttt
    27001 acctcttcta ttactgcatt tttaccataa cccatcacat cttgaaggat tctatataag
    27061 ttagtaattt cacctggtaa taatagtttt cttgccaatt cttttggtgt tggagcctta
    27121 aatttatcca ttagctcctt atttttaaat aaaagctttc catccaaatc acaaacacct
    27181 tctataattg taagcatctg catctctggt aagtctatat ccgttttcat attttcatca
    27241 attttaagac aagtattttg tatctcttca tctttactta ttgttaaagc tctacacatt
    27301 actttaaatt cctgcccaaa tatagttgat aatctcttaa gttcaactat agtacttggt
    27361 ctttctaagt tttctgtatc tgcatttaaa agtaaatcta ctatgtttat attttttgat
    27421 aatccatttt cattcattat tatttgctcc tttatcaatc aaattcaatc aactaacttt
    27481 tttacttatt aactacctga atttattaag tatatatcta ctaaatatca gtataaaacc
    27541 aaatataaaa ctaaattatg tcaagaaaat catactcagt aaatgtgaaa ggagcttcta
    27601 tctctccctt tactccaacc tcccaatcag ctaaagttaa atcatcaaat gctatatttt
    27661 ttactgctat tctttctgct ccataagaat ctgggtcatt taatttagat atagcaacaa
    27721 atctaggttc agaacctctc tttatctttt ctccaattaa cttgtgcatt cttgaactaa
    27781 catggtatag agttattgaa ccttttcctt tatatcccat atactttgta tcagtaccca
    27841 tttgacctgc tattataata tcctcttttg taaattccat ctttgcttga aacttcttta
    27901 cttctgctac tttatctcca tcaagccaaa gttctcccca agtaccactc attacatttc
    27961 tagcttccat atttgccata ttaataatcc tcctatatct ctattgataa atctatatct
    28021 tccatagcat ctaacatctt tatttttgct tttaagaata cttttgaacc tgtatttgct
    28081 tctcttattt cttgttcttt catattagat atatctatat ttttagattt caaatactgt
    28141 ttttgggctt ctatgtctat atctacaagt gaaccaactt ctattaattc ttccttttct
    28201 aattcttcta agtattcctt tattgccact attagtatgc atttattatc ataactatta
    28261 ggaactctac ctatatagtc atctattatt actttcttaa tgtcattatt tataatatct
    28321 aaagtgtcaa ctatttttat tttctggaac atttctcctt tttctgctgt taattcagtt
    28381 aaagaattta ctcctctagc aattcttata gctcctgctt ctttaataag tataagctct
    28441 cctttattaa cctttgattc tgcatcaact ttcgtcatct taggtatatc gactacatca
    28501 ctaagtttag tataagttac tgattgactt aaaggtgtac ctgctataag tccagccacc
    28561 ctacttgtaa actcatcaac actgtatttc ttttctccaa ctaacacatc ttctgtagta
    28621 aaattaatta tcccttcatg atttcctaca acttttccta atacagcttt aaccttaacc
    28681 ttatctatat ctctaagttt aattatccaa ttttttatag cagtcttatc agcttctact
    28741 gcttttggca tacatagata attaaattcc ttagtctcta aaaaatctaa tgcagtttga
    28801 atatctgctt ctccttctat tacataaact aataatttat ttggagtgtt aacatttccc
    28861 atcaaggcta aatttatata ttctttattt tcagcagata aatcaactgg tatatcctct
    28921 ttttcatgta tttcattaag acctagtgcc ttagcatctt taagcaccat tgcaattatt
    28981 cctctagctg aacgttcttt aacagttgta gctagctcct taaatgatat gttgatactt
    29041 ggtaatccta tagccatact atcactctcc taaatttaaa ttgatttctt ccatattttc
    29101 atatactaca tcttcttcat atacactatc cagatagttt agtgtaagtg taaagttcaa
    29161 tacataaatt gactcttctt ttttaatact ttgttctagc tttgttatat ttaattttct
    29221 gtctgttacc tttatatttc tgttaaatag cttatttaat tcatctgaaa cttcatacat
    29281 tctaatactc tttgactgtg gttttggtaa gtattttata gagataacaa tatctttgtt
    29341 attcgtattt aacattacag gtgtacaaat aactgatagt atacttacaa aaaaacaaga
    29401 cccttcagag ccttgcacac tttcatcatc aataaaaata ctttcagtaa agtttttttt
    29461 gagaatctca ataattgttt ctaatatttc cttgtattta agcaaataat caccacacta
    29521 tcactaaata ttcttgctta atctgataat cttactataa atgatataag tcatttttaa
    29581 atatatatct catttattcc tgtcaagtat cttctatatt tttaggtaat attattcttt
    29641 tcaatctatc acctccttca atatggattt ctttcacaat aacattatct cacatatttt
    29701 attgcctatt gttgcaatgg tgtatataaa gtgttgtaaa attgtcctat tttttataat
    29761 atctcactca atttaaatat catctttttc tttaaattgt agcaagatgt tctatctaag
    29821 tgtagtttca tagaaatata tgtcatattg ttttttgtct tactattata aaaaagatta
    29881 aaaaattcca tttctatatc atttagacac gttagagcat tttctatctt ctctttttct
    29941 atttctatat cttctttttc catttttaat tttcttaatc tttcctctct ttttaacacc
    30001 tcattttcca cagaagagct tatgttatat gtgttactag tcttttctgt atataccatt
    30061 gctccacatc cagagtattc attctcacat ctttttatgt ccaagttaat attctttatc
    30121 tttatatcca aatacttata attatgtaat cttttatctg tttctttaaa taatatatct
    30181 tttttgtttt ccatagtact tccccttttt tatatactta ttattagcct caaatttaca
    30241 ataatctctt tagtgcacag ttttttacta atctcatagc tttcaagaac atattgttct
    30301 ataactgtat aaaaaaaact tcttctatat tttgttctaa aatactggaa atcttcttag
    30361 ccataagaag tccaggattt tttatgcctc tttctatttg agatatataa tcatttgtaa
    30421 ttccagcctt tctggcaagt tgaatttgtg tcataccttt gcattttcta taatatttca
    30481 agttattttt aaacattgtt ttatacctcc attactatta agaatatttt gttcttcttc
    30541 acttagatta tatagaatta tttgttcttt atcaatagat tttagaaaaa aatattcttt
    30601 tatattttat tagttttatt ttttagaaca atttgttata atctatacat aaggtggtgt
    30661 tataatgttt gccaaaagat taagagaact tagaaaggaa tttggattga ctcaaagaga
    30721 acttggagaa aaagtaggcg tttcccaaag agtcttaggc tactatgaaa cagaaaacag
    30781 atttcctgat gaacacattt taaataaatt ggctgatgta tttaatgtat cagttgatta
    30841 ccttcttgga agaaccttag ttaaggaaaa tattgataca gtagctgcac atagaaaaaa
    30901 tccacatgaa gagttacctg aagaagcaca agaacaactt aatgattata tagaattttt
    30961 actaaataaa tataaaaaaa aataaaccat atgatgagca gtctattttt ctgctctttt
    31021 aatataattt aaaggcaaac atacattcta ttttaggggg atttttatga ataatttgga
    31081 taagcttttt gaattagctt ctcaagaaga gataataatt cattatacca cttatattgc
    31141 aggtgattta gaaggactat atataaacaa acatggtatt aaaattatat cattactcag
    31201 taatttaaaa caaaactcaa aaaaattgac atccatctta gctgaagaac ttggacatca
    31261 tttcactagc cttggatact atgtatcctc ttataacgat tattatacaa aaattattat
    31321 agataagtgc gaaaataaag ccttaaaatg ggcttgtgag ttcttaatta ctgaagaaga
    31381 tataataaac ataattaact ctggcatcac ttgcgtttat gaaatggcag acatacttaa
    31441 tgtggatatt actttctttc aaaaaagatt agaattttta tcattaaaaa aacagtcttt
    31501 acaacttgga aataataaat atttaatatt aactaatttg ccgtatttct acatatttga
    31561 tccaatttca taataaaaat agtagtaatt ttaactggct taacagtaaa atctatatat
    31621 ttattttaac aaattttggt ttctataaat tcaatattaa tatataataa tgatatcata
    31681 ttatttaaaa ttctaaaaac aaatatatgc ttttgttaag aaaggttgtt tgatgaatgt
    31741 ataaagaaaa gttgtttgat aattatttta agttcttagc actattattt tggccaatta
    31801 tgtggtataa gtggatagta atttcaaatg gtactcttga aaatatgtta tttaccatat
    31861 atgcaatcgt cgcaattgtt ttcatcattt tatattcggt gtttatgata aaatataaag
    31921 acattacaca aatagatttc ttttacagga taagtactct acttgctttt atatttacac
    31981 tttttagctt tttaatatac ccaaagagtt tatttttctt gtatttaaag attattttta
    32041 ctggaatata cctttattat tcaatagtaa aaactcttaa atttaaagat gacgaaggtg
    32101 tagtgggtat tatgagctca cttttattaa ttgtaataac tttgttctac taaatttaat
    32161 tctatttgac ttaatatggc tttaaatatt agacatctac attattttct gatattattt
    32221 aagatggtag tcttatatta ataatgaaat acactatgaa ggagttaact attatggaaa
    32281 aaaaagtttt agcaacagtt ggagaaaaag agataactaa tattgatatt gaaaatgcat
    32341 taaaatcatt agacccttat caagctatgc aatttaaaac tgaagaagga aaaaaacact
    32401 tattaaatga tttagtgaat caagaattat tcttcttaga tgctaaagaa gaaaaattag
    32461 atgaagaaga aatatttaaa ttagaaatga aaaagataga agaaaatgta ttaaagcaat
    32521 ttgccataaa taaagtttta tctagtgtta atgtaacaga agatgaaaaa gtaaaattct
    32581 ttgaagctaa taagagctct ttctctaaac cagaaagtgc aactgctaaa catatattag
    32641 tagatagtga tgaaaaagct aaagaaatac ttgctcaaat aaaatcagaa gaaatatctt
    32701 ttgaagatgc agctcttaaa cattcttctt gcccatctaa agatatgggt ggtgatttag
    32761 gaacattcgg tagaggacaa atggttcctg aatttgaaga agctgtgttc tctatggcta
    32821 aaggtgaagt aagtgaacca gttaaaactc aatttggata ccatataata aaattagaag
    32881 accttcaaga aagtacagag tctacatttg atgaagttaa ggctgaagtt gaaaaaagtt
    32941 tattatatca aaaacaaaat gaagtttatg gaaataagat aaatgctctt aatgctaagt
    33001 acggaaacct tgtaaaatac aacgattaat cataaggtca catataaaaa agctgtcttt
    33061 tcacaatatt tattagaaaa gacagctttt tatattaaag tttaaatatt cagtttcata
    33121 ttatcattct tttattgtaa agaactcagc ttaaaagttt aaataagatt tttaattatc
    33181 attagctaaa tttttatatc cacgtattat ctcataacag taacctatta catctcttct
    33241 ttttattatc ccaataaatg tgtcttggtc atctataaca ggaatgaaat tttgatttaa
    33301 agattttata actaaatctt caatatctgc gttgatggaa acaggagaat tatccatttt
    33361 tctatttata tctgtcactg gaacatcttc caatcccttt aagtccagat ttaaatcatt
    33421 ttttaatgtc cataaaaaat caccttctgt tatagttcca acatatttac catccttact
    33481 tattattgga attgcagagt atttgtgata ttccattttt tctagggctt gccttatagt
    33541 gtagtcttca tatatatatg ctacttcact ttttggtgtt agaaagaata atatgttcat
    33601 tacactaccc accgttactg aaaacttata aatattactc aatatttata atgttacttt
    33661 tttgcagtaa ctttctcctt tcttattttc taagtattct taatactata cgctgtaaca
    33721 agcgtttttc ctttgctcat tttaatctta ttatgcttta ttaatatttt tatatggtct
    33781 atcagtatca cttattctct ttttagaaaa tttactaaaa attaattgac ttaaacttag
    33841 ccataataat tttactctac actattaatt ttaacatatt tatctcatta ttaatgattt
    33901 tattttaata attttaattt attttgctat taattttatt tacaaaaact gaaaaaaccg
    33961 ctaaatgatt agcggcttat ctctcatatt actagaacac taatatatat gaatttttaa
    34021 ttataatcta actacgttag cagcttgagg acctttagct ccatctacta cttcgaactc
    34081 aacgctttgt ccttcttcta atgttttgta tccatctcca gttatagctg agaaatgtac
    34141 gaaaacatct ccttcacctt ctacagatat gaatccaaat cctttttcgt tgttaaacca
    34201 tttaactaca ccagttttca ttaataaatc ctcctaaaaa aacacaaata tttagctact
    34261 cttttctgta accttattac tactctatca tatatagcta tgtttgtcaa ttattattat
    34321 ttttatacat taataatcaa tttttttact ttataatttt aaatgattat tatcttttac
    34381 actttatttt tctttataat tttttaataa tttattttta ttatatggaa tcttatggac
    34441 ttatcactcc aacctaaatc ccatggcacc aacattctat cagtattatg acaagttacc
    34501 aaaggatacc ctcttgagtc taatcctgtc actgtcgaaa catgtgttat tctgcctttc
    34561 ttctcataac caacaaaatc ccctggacgt aaattataag cttctttgta tacttcttca
    34621 taggaacctt tagcaattaa tgaacctctt ccactataca gtgcataatt tttaaaagct
    34681 tgtgcattta cccatgcttt tgtacctgct ctctcgctat aattccaaat tgagttcttt
    34741 ttgaaccttc cactttcaaa cattatctgt gatgcaaagt ttgcacaatc tccaccttct
    34801 ggattataat ccctatagtt tggattaaat ttcataccat gttcttcatc agctgcggct
    34861 ccacagtatt tatgtgcata atctatagcc tttttttgtt catctgtaag ctgtaactct
    34921 acaccatctt gttgaccaat ataatttctt atatcatcag attttatatt ttctaaattt
    34981 aaagagtctg caaaagggtc tgtataccac tctttagtta tgacatattg attatctata
    35041 atttttacat ttagataatg atatgtacct attctaaagg cattttcttt gtccttttga
    35101 ttttcatatg aatacttata ttcagtcgat actgaacaga ttataccata gaggtctttt
    35161 tctttttctt ttattttttt aatcttaacc cttgtcttta tgtctttaaa ttttacacct
    35221 tgcttactag accagttttc taaatacttc atctttttta cttcattttc ataagcccac
    35281 agaccaaatt ttttatccgt ctcataaaga ccttttaaaa tgttttcatt tttctctaat
    35341 atcgccttat ttctgtagtc aaataagttt tcaagcaata gtttatattg gtcttttaca
    35401 tcatcacctt caacatttgc agattccatg actttttctt ccatattttt catacttaaa
    35461 tcattgatta aaaatacacc tgctgtagta gctaaagaca aaaatacaaa tgccattata
    35521 cctttgatgt acttattctt atttttcagt attttcaaag ctacacctcc caaatagtac
    35581 accttacaaa tcaaattaca aagaatattc tgtcacatat agtaattttc atatttaata
    35641 attctctatt ttattatgtc caatattaaa aattaattgt atcaatacac tgtttttttt
    35701 acaatttttt attttataat ctactttttt ctttttttta tagtaatata tatgtatata
    35761 aatattttgg tatcattata attaatacat actaatggag ggttttttat gcaaaaaaaa
    35821 gtcgcagcaa ttaatgactt atctggaata ggaaaatgct cattatcggt tgctatacct
    35881 atactttcag cattaaaggt tcaatgttgt ccatttccaa cggccatact ttcaagtcaa
    35941 actggttatc ctgaatttac tttcttagac tttactgatg aaatggtaaa atattcaaat
    36001 gtttggaaaa atttaaaagt caattttgat agtatatata gtggtttttt gggttcaaag
    36061 catcaaattg agatagtggc taattttata aacgattatc ccaatgcttt tatcgtagtt
    36121 gaccctgtga tgggtgataa tggagttatg tatccaatat tcacagaaga aatgagacag
    36181 gaaattaaag aattagttaa acattcagat ttaactactc ctaacttaac agaggcttgt
    36241 ttcttgactg gaaatgatta tactaaaagc gattataata gagatgagct tatacatatt
    36301 gcaaaatctg tatctgattt gggacctagc aaagtcgtta ttactggtat attagaagat
    36361 gataatatat taaatttggc ttacgataga gataatgacc atgtattctt tacatcagtc
    36421 aaatataata attgttctta cagtggaact ggagatatat tcacatctat actttgtggt
    36481 atgttagtaa ataaacatga tttgggagta gcggttaata ctgcaacaga ttttatatat
    36541 aaaactataa attacacatc tcaatttgat actgatagaa atgatggagt tatgtttgaa
    36601 aactttttat cagatttaac taatatataa aatcaaaaaa actatccatt ttataaatac
    36661 ctataaatca taaaatttag gtatttacaa aatggatatt atttactaaa ctattggtat
    36721 ttcaattgtt accatagcac caccagtttt cacagaattt tcaatacata aagtcccatt
    36781 atgtttttgt acaatattat ttacaatata gagtcccatt ccataatgag atttagaatt
    36841 tctactcaaa tctcctgtat aaaactgttc tgtagctttt gacaaatctg ctttagaaaa
    36901 accacttcca caatctgtaa ctacaaattt taagtattta ttacatactg atacacttat
    36961 gtatagttta ctctggcttg gtgaataatc tatagcattt gaaattatat tcataatagc
    37021 tctgaataac agttctctat ctatagttat atttttaggc aaattatctt gtttataaaa
    37081 ctccacatct aagtttttag tactagctaa tgcttctatt tgcactaaga catcttttat
    37141 aaactcactc atactgattg cttctttatt taatatatag ccattctctg tttttgatat
    37201 atctattaaa gtattaatat atttttctat ttgagtgaca ccctttgaga tatattccat
    37261 gtattctaat aactcaggat tttcatttat ttcaattaat aagtcagtat ttccatgtat
    37321 aattgttagt ggtgttttta tatcatgtgc cagtgcagat atctgttcct ttctattttc
    37381 ttctagcatc cattgttttt ctaaagaatc ttttaacgcc aacttcattt tatccataga
    37441 aaaaaggaca ttattaattt cataaatttt actagattct acaacaaaat ctaaatcctg
    37501 ttgttctatt ttttctgtag tattttttaa aagctccatt tcaatattaa atttcttgcc
    37561 aaatactttt gataatataa caatttcaat aaaaaatatt atactaaaaa taatcatacc
    37621 caatgtctct ggttttggta aatatgctct taaaattgga gaactatact ctgatactat
    37681 tttgtatttt attataaaaa cttcatcttt cttaaaaaac tttatataac tttctgaata
    37741 tgcatgcctt tcttcaatat ctctcattaa attccatact tcttttgatt cttttttatt
    37801 aaaggtacct gaaattaaat tcccatctaa agtataaacc ccatactcat atatacttgg
    37861 aattatatct tcagttactt tttcacttga aataatctgt tctttatatt tattgaattg
    37921 tttttctgca taattagctg gtaaaattac acctgatgat aataatacag aaaatgataa
    37981 cattaaaagg agtacaattg aaattgtcat aataaagaat aaagataaat attttataaa
    38041 aatagttctt aacttttcaa cttttttgtt gttagatttt ttacctccaa gcatttgtac
    38101 cctgtcctcc aatagtttaa ttaattcata attaatacct agccagtttt ttatttgatt
    38161 attttatatc tttttattgc taagttatat tttaacataa taatataaat aaacagtcaa
    38221 tttttactct attcttctga ttttttacct tcccatttag aaaaccaaat acataaaatt
    38281 acaaatgcta aaattgttac aaaaccacaa attaaacctg ttgattgata tgcttttatt
    38341 gattcaacct ttatatattc aaccgtttta gaacttgaaa aagacgacca aatagttata
    38401 aatctaacac cccatgcaca aggaaaatac tgccaaatac cagaacccaa tccagttaat
    38461 aataatgctg aaagtaacat ttcaactata cctactccaa ttgatgctcc ttttccgaac
    38521 cttaaactta agaataaatg taatatgtat tcaaataaat tacacccaat taaaattaga
    38581 attgaaatca tataaaagct tgatgtaaag taagccttag atataccaaa tttaaaacct
    38641 aatacagaca ctaatgttgc tacaaaacca agacatacta agattatata tttacttata
    38701 agagtaagat attttggatt agatgttgtt aacatatgtt tataattccc tgcataatat
    38761 tcttgttcaa caaacattga acacacaaca cctgacaata aaggaaaagc tattgctata
    38821 acttgtaaat atcctactat ctttagtata ttatcagctc ctgaaacctt ataataccat
    38881 aaaaacaatc ccatccccat taaagcaatg caaatgtgca ttagtattat aaaatttctc
    38941 tttaatttta ttaaatcaga acaaaatatt cttattaact gtctcatatt acttcacctc
    39001 tctattattg aaccaaaccc ttgtagctaa agcaaataat acaaataaaa caatagatat
    39061 taatactcct ggcaaaataa cagcattatt taaaaattca cttccctctg gtacaggaag
    39121 accatttggc agaatatgca atacaacagc cattaatctt gaaggaatcg aatatggaaa
    39181 catataccac atttctgtag ttgagaaaac agcaactcca acaatagtga agaacatatt
    39241 tattagaact gtaacaaata taccaaattt tgaagctaaa aacatacaaa gaggaatctg
    39301 ccacataaat agtaaaataa ttaatatagt tgcaatgata ttttgaccta ttgaaatagt
    39361 ttctttatag attatcccaa caaaaactac acctattgca gaaataattg atgctataaa
    39421 acaacaaata atacagtaaa tcatttttcc agtccaaacg tctttcattt caattggcaa
    39481 gggtaaaata ccacgatatt tacttttttc atcttttaat actattaaag aagatattaa
    39541 tgttaatgct cctggaagaa atgtcgtata ccaccagttg aaagcagcat tttgccctcc
    39601 acctagtcca cacaaaagta tacaaaacac tggaactatc catatcaact tcattccaaa
    39661 agttcctttc atcttttgaa attccactct aataaatctt tccatattac tcccctctct
    39721 ttctattttc agctacaact ttcataaaaa gtttttctaa gttttgttct tttgatactt
    39781 ctccttgata acccattact ccattagaaa ttattcctat ttcatctaca acttgttcaa
    39841 cttcagacaa gatatggctt gataaaataa ctgtaattcc ttgttttgga aaagaacgaa
    39901 tcaattctct aagttcttca ataccaatag ggtcaagacc atttgtaggc tcatctaaga
    39961 ttaaaagttt tgggtgattt aataatgcaa tagcaatacc aaggcgttgc ttcatgccta
    40021 gagagaattg acctgaacgc tttttaaagg tatctcttaa atctacagtc tctaaaactt
    40081 cttcaatgcg agagtcagga agaccaagta aagtagtatg aacttttaaa ttttctcgtg
    40141 ctgttaaatt ctcatatata gcaggagact caataagaga accaatattt gataaatcct
    40201 ttctagtcca tctatgtccc tcaaacatta tttttcctga agttggattt aaaatcccag
    40261 ttatcatttt taataaagta gatttcccag ctccatttgg tcctaataat ccatatatag
    40321 aattagattt aattgctagt gaaatgttat caactgccat ctgctcctta aattttttag
    40381 aaactccttt tacctgcaaa atataattac tcataatttt catcctttct tttgtcaaac
    40441 ttatttacaa gaatcattct aaatcataaa tataaggatt ttataagaat taaaaaacaa
    40501 aaaaagatgt gttaaaaaca catctttttt tatcttaatt ctattaattt tccattgtag
    40561 tatatctcta cttcttcaat ccaaatgcta ttatcttctt cttggatgac atttttaata
    40621 atattattta tagtatatat tatattttgt tcattcaaat aatcatcttt ccaagaaact
    40681 ctactttttt tatctggttc tatcaagttt attttaacaa gattatcttt ttccttaact
    40741 tctacttcca tgtctaaacc attaaaatac tcatttgata atgtatctaa gattaatcgc
    40801 agtttatcct taagtgaact ttcttcatca atctgtaagt actttactat tttctcatcc
    40861 tttgaaatta tctctatagg tattttagta gtttttttag aattaatcat tttactagtt
    40921 gtttcttctt ttgcatcttc atccttcttt acaactgctg attctttaga atcaactagc
    40981 tcaactgcac tgatgctata atccatacat gccgtactca ataaagtagt agcaattatt
    41041 aaaaaactta ctgctatttt attcataagt atccctctcc taattctctt tcgatactta
    41101 ttataccata gtatagatta tatttttata cttttaaatc aatttataaa ttattatagt
    41161 aaattattta caattctaag ctatttgaat ttatttttat agtatattct ttctctaaat
    41221 tcgacagatt tttattcaaa agccctttta tttccctcgt atttctatac ttgttgctat
    41281 gttcttcatc atgttcatag tcatatgaat cattgtcata ttcttcatca ttattaaatt
    41341 cttcaattgc ttcttttgac tttatatcac aattaaattt atacttattt actggtatat
    41401 caagtcttac cttagaattt ggaacttcta tgtccaggaa cttagcaatt ggcatatcag
    41461 agtacaagta aaattcactt tcataatttg aatttctacc tattttctct tttatattta
    41521 cattttcagg tatatactct tctatattat tgataaatac atcttcattc tctgaagata
    41581 tatacaatga ctctgattct atgtttacat ttttaacgcc taaaattgat tttgttgaca
    41641 agtgaagatt gttattagat attaagttta ggttttctaa tctatttact ttgttctctg
    41701 ttatagctct actaaaacct ccataagaag ttttatatgt tatagtattt gaagctacat
    41761 tatcgtatac aaataagtgt gagcttatac ttgatgcatt tatgtctaca ttatttggta
    41821 catatattat aatttctcta taatcatgtg aaaacatact atttatagat gtatttaata
    41881 attggtcgaa atttttaatc tttttaattt tattttcata ttttctttca ccttttacaa
    41941 ctaaagtctt atcttttaaa gttacattgt atttgtaaaa ctcattattt cctcttgttg
    42001 ttacacgcac atcttcactt gaacttttct ttattgtaac gtttatattg tcaacagcta
    42061 tatctaactt gtcaatattt actttttctt gataaagttt attttctttt ttaaattcag
    42121 cttccttttc taaaccaaag tttattaggc ttggcataac taaaatccct gaccatgttg
    42181 tccctattat acctattacc aataaaactg cagcaaatat agcaagtttt ttattcatgt
    42241 ttatcttctc ctttcttatt ttctatatct tcaaggtcct tatatatcgc ctcaaaattt
    42301 atactatcat cattatattc atcagtttct tttatgcttt cttcttctct attgtagtaa
    42361 tcattattat atgaatcttc attaatgtct ttattcaaat cttcattaat gtctttattc
    42421 aaatcttcat catttaaagt agcttttttt cttttttcca tcttttcatt tgcctttata
    42481 taaatatttt ttctctttat ccaatgtata taattattta gtaattgttt acctagtttt
    42541 atggcaaata ataaaatttg ccatgcaagt atctcaagcc ctacaaatgc tatggttgcg
    42601 aaaatacaaa acatcataac atctggaacc attgctataa atttaatcac aaatggaatt
    42661 aatataacaa aagcaattaa tgagcatact aatgcaatag tagcagatac aatagcacat
    42721 acaaacgcaa atgctggaac aattagaaat aaagataaca ctactaataa cccctttata
    42781 acttgtctgg ataatcctcc tacgccttct tctatacttg gtgtaagttt atcatttata
    42841 ttttcttttg atttattgta cttttcctta gcttcatctt tcaagataga gtaatccttt
    42901 tttacatttg atttaaatct actaaattta ccatttaata tgtctgtatt cattattttt
    42961 ccatctatat tttcttttga tttactatac ttttcttttg cttcatcttt taagatagag
    43021 taaccttttt tcatatctga tttaaattta ctaaacttat cattcaaaac atctgtattt
    43081 attatttttt cctcttcaat atttttttct ttagtttgta agataagttc ttttgctata
    43141 gattttggtg agccaagtga tgctattatc tccatatcac tctttccctc tataagacca
    43201 tctacgaaat actcttcata atctctcaat atatcattaa cttcgctctc agaaaaatct
    43261 ttttttagat aatcctttaa aatttcaaga aactcagttt tattcaagtt cattacctcc
    43321 ctcatcttca cttattaaaa tctcaacagc ctttacaaat tctctccact cttccatcag
    43381 attggataaa ttctcttttc ctagtgaagt tattctatag tattttctag caggaccttc
    43441 attagattct agtatatatg tttcgaaata caaatctttt gtaagtcttc ttagaatagg
    43501 atatattgtt ccttcattta catctattac tttagagatg ttatgtacta tctcatatcc
    43561 atacatatct ttcttagata tgagagcaag tacacaaatt tctaaaacac cctttctaaa
    43621 ttgtgtgttc atatactcca tcctttcttt aaatacacag tattgtgttt tacaaggtac
    43681 tatgttaaaa cttcttatat cctcataata acacagtact atgttctgca caatagttat
    43741 ttttaaatat tcttgttgat taaatccttc tataaatgta taatactcta atcagatata
    43801 ttttatgaaa gtggtgataa attggctaaa atgaaagatg ataaaacaat attaatccta
    43861 actgctcaat ttggtgctgg acatataagt gctgcaaaag cagtcaaaga atgtattatt
    43921 gaaaaatata gtaactataa tgttgttata caaaacttta taaatgcaag tattcccatg
    43981 atgaataagc ctatggtaaa actttatgaa aacaatacaa aatatactcc tggattatat
    44041 aattactatt attactttaa gaaatcgttt gattcaagac atgatttatc tcataaatta
    44101 tatacaccta aactttctga gtatattgct gatataaatc cagatttgat tatctctaca
    44161 tttccactag ctgctgcttg tgtaaataac tttaagataa aaaatcctga tataaatata
    44221 cctacactta cagttataac agatgttgta gatagtatgg aatgggtttt tgaaaataca
    44281 gatttgtatt ttgttccttc tcctgaaata aaaaatagat tttttcagaa aggaataaat
    44341 cctgactcca taaaggttac tggagttcct gttgataaga gatttcaaat tgaaagtaaa
    44401 gaactatgtt gtgataaata tagactatta cttctaggtg gaggaagagg tctatttgat
    44461 atagatgagg attttatgca ttggatagat gaatttattg aagaacatag taattctata
    44521 gaaattacaa tagttactgg taaaaacaaa aaattatatg acaatctaac tcataaaaaa
    44581 cctctaaaaa atattaaagt acttggattt gtaaacgaca tgtataatct aataagagaa
    44641 tgtgacctaa tgctaactaa gcctggagga gcaactatat ttgaagctat tcaatcacaa
    44701 actccagtac tcgtaaaaat gccaaaagtt ggacaagaaa ttgaaaacgc taaatttata
    44761 atagataagg gtcttggcat gatttatagt gatgacctag accttaaaaa catattttat
    44821 aaattagtat caaatgaatt tgattctata ataaacttta tgaaaaaaaa tttaaaagaa
    44881 tttaaaacag tcattcatcc agagaaaatt gctgattata tatcagaatt aatagataat
    44941 cattacagtt aaattgtact attaaaaaat ttcaaacata aaattaaagg caatcaagta
    45001 tgcttttaca cttgagaatt tactcatagt gtttaataat acttgattgc ctttatcata
    45061 tcaaaatcaa attgttatat tagtatatat ttttcttgta ctgcatatac agttgttgta
    45121 tttcttccat acttctcttt aattctattt gtaaatctga agcagtctgg taatccttat
    45181 tttctatagc ttctctcact ctagtgaata gtgattctct agttaaagta tccttcataa
    45241 tattgaactt taaatccgat attgagttcc aaactacctc atcaagcgca tccatatttt
    45301 cttttgtgtg tatcttgaca atacttctta ttttttgaat cccagcctct attattctag
    45361 tttttaattt cttttgccac ttatctatag ctccaatctt aaatgattct attatactat
    45421 cagtaaatac atcaccttgt tttaaagatt ttaattttga agcatatatt tctaagtttt
    45481 tcatattttc ataaactgta gctggtggta ttccaaatct tgcatttctt tcttccaaac
    45541 tataatgttc aaatacatca ttttcatctc tatatgctct atctttttct aaatagaaac
    45601 tttcttcacc tacattttta gataactctt tttcaagttc ttttgtacta agaccactct
    45661 tagctgctgc ttttatacca tccaacattg tttgataaca tcctgctatt actaaatacg
    45721 tgttagatag agggcttggt gaccttaatt caaatcttac agtctttgga tttttcatat
    45781 ctcttattaa tccaacaagc actgacctat ttcttgatgg aatctcataa ctatgcccta
    45841 aagatgtaac tatgcataca ggagcttcaa atccaggaac taatctatta aatccatcat
    45901 tagaagctgt tacaattggg tttaatactt cataattgta aagaagtccc ataagagccc
    45961 catatcctag ttcacttaga taatcttctt ttaaatcttt tggagcaaat agatttttta
    46021 tacttccatc ctttaacttc gcacttactc ctacatgtgt atgtccacca cttcctgcta
    46081 ctccatgaat tggttttgct ttaaatgtaa cttctagtcc atgtgatgta aatacatcct
    46141 ctataacatc tcttactaat aattcattgt ctgctgcttg taatggtgta gaaaacttcc
    46201 aagaaacctc taattgctcc atagcatggt ttgttcttcc atctatacta atagaacttt
    46261 gtattcctcc gacctctttg tgagccattt cagggtttac acctagcttt tgaagtataa
    46321 ttaaactttt ctctaaacaa gttcttataa taccatgagt tcttttccag tattgctctt
    46381 ttaggctttg tgatacatat aatttctcta agtcagcttt atcctcagga gtattaaccc
    46441 agaactcaag ttctgtagct gctgttaaca ttatttcctc tatatcatct actgaatcta
    46501 ttcctatgtt atttattaca tgtggatatt ctctaaatat ttcatacatt gactttttaa
    46561 agtacttatc tgctttttga agtactcctc tagaacatac ttttttatta tcatgtatta
    46621 aaaatgcagg tatctttaat gttccaacag gtagacctac ttcttcgtct atatattcca
    46681 tattgtaatc tacataccaa tgacaacttt tatctggcat taaatctact ttcgcattat
    46741 ttaatgtagc tatattataa agctcaacac ttgaaccatc agtctgtata gctgattcca
    46801 aaaatttatc tatatcctcc aaaaataatt ctacaggaat cttttcatct gttgcatttc
    46861 ctcctaaatc aacccccatt aaggaaacaa atcttatatt tttattgctt tttaggattt
    46921 ctcttaattc ttcattagtg tgtttatctt tctctattac gtataataga ctatccattt
    46981 ttccactctc ccataatttt tatgtatatt ttattttgtt aaatacaaga taaatttcat
    47041 tttccttaca tttatgaatt tttcttgcaa attattcgtg ttttattcgt gtttttattt
    47101 atattattat atatcaagta taaaaagttc gcaatatttt ttattggaaa aaatattata
    47161 catacaatag tttaacattt ttacaaatat ggggtatact aaaataaaag tatttttatt
    47221 tgaaaattta attttattta taatataatc tatagtaaaa gaaataataa aaaaatttag
    47281 gagataaact ttatggaata cataattttc gatttggaat ttaaccaagg atttgataaa
    47341 aaactcaata aaactgtatc caatgaaaag tgtccttttg aaattataca aataggagca
    47401 attaaattgg attctaaatt caatataata gatacgttta atagctatgt aaaacctaca
    47461 atttataaag acatacatcc ctttattagt cgtatgacta atattaaaaa ttctgatttt
    47521 aatgattcgc ctactttccc tgaggtctac aacaatttta taaaatttat atcatcacaa
    47581 gaccctatat tatgtgtttg gggagctgga gatttaaagg aattatacag gaatatcaac
    47641 tatcacaagc taccatcaaa ttccttacct aaatcttata ttaatataca acaacatgca
    47701 tctaaatatt tcaataatcc agcaggaaaa agcattggcc tacaaaatgc tatttctata
    47761 ttagaacttg atgaaaaaat gtcttatcac aatgctttaa atgatgcata ttatactgct
    47821 aaagttttta ttaagatata caatccaagt atagtcccag atatatatct ttatacgagt
    47881 ataaaaccta aaactataag atattctaat aaaaaaagag ttgattatga taagttattt
    47941 gatgaattta ggaaaatttt aaatcgtgaa ttaactaaag acgagaaaaa aatcattaac
    48001 ttagcttata atatggggaa aacaaatcaa tttacattag aaaatgttaa gcaaagaaaa
    48061 aacaaataga gtttatttag ataaaaaata ggcatgtaga ttaaaaaact agttaacttt
    48121 aaatttatat ctacagccca atttttatca taattaattt ttattttatc tctaattcaa
    48181 ctggacaatg gtctgaacct aatatttcag tgtgtatatc cgcacttact aatctatctt
    48241 ctaatttttt ggatgcacaa aaataatcta ttctccaccc tgcattattt tttcttgcat
    48301 taaatctata tgaccaccaa ctataaacac cttctttatc aggattaaaa tatctatatg
    48361 tgtctataaa cccactgtct aataatttag aaaacttctc tctttcttct ttagtaaaac
    48421 ctgcattttt catattattt ttaggatttt ttaaatctat ttctttatgt gcaacgttca
    48481 tatctccaca cacaattaca ggcttatgat tatctagttt ggttaaataa tctataaagt
    48541 cgtcttccca tctagttcta tattctagtc tctttaattc agattgagaa tttggcgtat
    48601 atactgtaac aaagtaaaaa tcttcaaact ctagagttat cactctaccc tctttatcat
    48661 gttcttctat atttattcca tacattactt ttaaaggctc tttttttgta aatatagcag
    48721 tacctgaata accctttctc tcagcataat tccaatattg aaaatatcct ggtaaatcta
    48781 actctatttg cccttcttgc aatttagttt cttgtaaaca aaatatatct gcatctactt
    48841 ctttgaaaaa gtctaaaaat cctttcccaa cacaagctct tattccatta acattccatg
    48901 atataaattt catacttata ctcctcatct aaacattgac acactcccca tagctaaaga
    48961 tgggggcttt tcaacaattt tattgtaaat tcttaattca cttttatttt aacaatgcta
    49021 tactataatt tcatctaaaa ttactattta cttaatacct aaaaatatat gttttaatca
    49081 atttttaact tttttgttaa atcttcaggg ctcattgaag aaacatacat atttgttcca
    49141 agttcaaatc ctccaaaatt atattttctt gggattatgt gcatatgaac attaaaatac
    49201 gattttgttt caatctttgt tggatgagtg tgaatacata aattaaatgg catatatcca
    49261 ttgatattgt ataacttctt aaacaacttt tcaaatattg tagaaagctc ctgtatatta
    49321 ttatcattta actcaccaaa ctctatttta tctttaaata ttattcttac ttctccacta
    49381 tacttggttg catatggtat aagtaccaaa aaagcttctc cattataaac aactcttcta
    49441 tctaaactta tttcattttc tattaaatca tcatacaaag agcttttatt gctgtcataa
    49501 tactcctttg aaaccaacag ttcattcgta atttcaggtg gaataaaaga catagacaat
    49561 atttgtgcat gtggatgcat caaagatgct cctgcctttc tcaagaagtt tttgaagata
    49621 ctaacatact ctactttatc atctttcgac aaatctctaa atctatttct atacataaaa
    49681 aaaacatctt caaattcttt ttgactcatg ttataaaaac tacgattatg tttatcgctc
    49741 tctatcatta cttcatgaac accatataca tctcttgcca tatcatcaat tataggaaat
    49801 ttattgtaga cagattttac aagccatcct tcttcactat ctatttcaaa taatgcatca
    49861 gttgcatgag cttcatttcc tttgcaaaat gggcattctt catcatattc attagtttct
    49921 tcatcttcat ttgggatatc tgctgtatct aaaggtcttt ttaacctatc tgtagcaaat
    49981 ataacaacat cattggtaat tggatctatt cttaattctt tcataattaa cacctcttag
    50041 ttaatagcct ttaatataat tatatgatat ttatcgtatc tgttaaataa atttataata
    50101 ttttttataa ttttgcatat ttattattat atattttgtc tatagctgaa agattataac
    50161 taaaaaatca ctatcagtat atcagaatat tatcttacta taaattaatt tatgaataca
    50221 taatttagtg gcataaacat gggtatttta ctataatttg ttaaaagttt attttaaagc
    50281 tatattaatt ttttttgatg atttttaccc ataagtatgt tattattatc ttgtaaagat
    50341 gtcttgtatt caaacataca atttacataa tacaatatac gtatttaaat taaatagggg
    50401 gtattaaaat gaattattca aacagagtta gtgcaatgca agcctctcca atcagaaaac
    50461 ttgttccatt tgcacaagca gcaaaagata aaggaatcaa agtatatcac ttaaacatag
    50521 gacaaccaga cataaaaact cctaaaggat tttttgatgc tgttaaaaac tttgatagcg
    50581 aagtcttaga atatgctaca tcagaaggta ttccagaatt attagaagca cttcaaaatt
    50641 actataaaac ttacgatatg aattttgaaa aagatgaatt attagtaact aatggtggta
    50701 gtgaagcttt acttttcact atgatggcag tttgtgaccc aggagataat ctattagttc
    50761 cagaaccatt ctatacaaac tacaatggat ttggtcaatc tgtaaacgta gaagttaatg
    50821 ctgttacaac aaaggcagaa aacggtttcc accttccatc taaagaagaa atattgtcta
    50881 aagtagatga taaaactaag gctataattc tttctaaccc aggaaatcca actggtgcaa
    50941 tttatacaaa agaagaactt aatatcctag ctgaaatagc taaagaaaaa gatttatgga
    51001 taatagcaga tgaagtttat agagaatttg tttatgatgg gcttgagtat acaagctgtg
    51061 gtaacttaga gggtgtacag gatagagtta taataataga cagtgtttct aagagataca
    51121 gtgcttgtgg tgctagaatt ggttctatcg cttgcaaaaa taaaggtctt atcgctcaaa
    51181 tccttaaatt atgtcaagga agactttgtg ttcctacatt agagcaaata ggagctgttg
    51241 agttatacaa aactcctgtt tcttacttca aagaagttaa tgaagagtac aaaaaaagaa
    51301 gagatgtatt atacaatgaa ttaatgaagg ttgaaggtgt tatatgtaaa aaaccaactg
    51361 gtgctttcta tatagttgct aaattaccag ttgaaaatgc agaagatttc acaatttgga
    51421 tgttaaaaga atttaacaaa gataatgaaa cagttatggt ttgccctgct gaaggattct
    51481 atgctactcc aggtttagga cgtgatgaaa taagattagc ttacatctta aatgaaaaag
    51541 accttcatag agctgctaca ttattaaaag aaggtttaga gcaatatgta gctttacaaa
    51601 aataattttt taaacttaat ttatataaat ttaatgatat aaaatgtccc cttttcagat
    51661 attatttgaa aaggggacat ttcttaatta atatattaat taagacttag acctgactat
    51721 ttttcatttt ctttatatag tgttggccag taatctttat tcactttaat taaagcatct
    51781 aaaacttgtc ttgccttagt tagagaaatt ataaaaaagt acatcaagaa aatttaagat
    51841 gtacttttta gattgtattt agacttataa ttatatagtt aaatgaataa caaagaatta
    51901 atcttagtac cattaaatac aaaaattttt atattttttc tatctaaatt cttctttgtt
    51961 taatatatat tgaagagtat ttattgcttc taaatatttt tttctgtctt cttcagttaa
    52021 tttagaaagt ttttctccta aaccatcact taatttatcc ataaaatcag ttgctatctt
    52081 atctccctct tcagtaatgt caattagata ttttcttcta tcaactaaat ctcttttcct
    52141 tgttacatac ttcttatcag ttaaatcatc aaccatacta gttaaactgc ctttttctat
    52201 atttaactta gagcataaat cagtcatact tattactcca taatttttta tgaaaactaa
    52261 tgctcttaat tgtgttttat ttacattata atctggtgca aattttttta ggtcttctaa
    52321 gtacaggcta gaataaatct taggaaatgt ttttactaaa aaacttatgg tatcttttac
    52381 tatatagttc atataatcac ctcggttgtt ttaaaattta ttaaattatc taaataactt
    52441 tatttcagtt tacattaaaa atattgcaag tacaatagtt tttgctgaat gtttaaattt
    52501 aattagtaat cttatcattt ttttattttt atttatatta ttcctaatta aatattattt
    52561 atatagctat tttattaaat tcatggtata gtaagtaaag aagaactctt cacagcggtg
    52621 gagagaagac gctagcccat taaaatggct atcttattta taaataagat agccgttttt
    52681 aattatattt tatctgtaca attctatact cttaggtcta catctacttt tcctaagtct
    52741 tccttataat cttttatagc aggttctaca acttcattta caaattctac aacttgttct
    52801 ggagctctac ctataaagtt ttttgggtcc attatagata gtatttcttc cttgctcatt
    52861 ttaaatgaat catcatttat tataagttca attaagttat tatccttgcc ttcatgcttt
    52921 actctatagg cagctttcat agaatattct cttattattt catgtaattc ctgtctatct
    52981 ccacctcttt ttacagcttc cataagtatt gtttctgtag ccataaaagg aagttcttca
    53041 tttacacgtc tatttatcat attttcatat actactaaac catcagttac atttatccct
    53101 atttcaagta tagcatctgc tgccataaat gcttgaggta ttgccaatct cttattggct
    53161 gagtcatcta atgttctctc taaccattga gtggcttgta ccattgcagg gcttatagat
    53221 tcagagatta tatacttaga taaagatgct attctctcac ttctcattgg attcctctta
    53281 taagccattg ctgatgaacc tatttgattt ttttcaaatg gctcttctaa ttcttttaaa
    53341 ctttgtaaaa gtcttatatc attagtcatc ttatgcatac tttgagctat ccctgatagt
    53401 atgcttatta cttgataatc taactttcta gtatatgtct gtccacttac tgcataggaa
    53461 gaatggtatc ccatcttttt acaaattttc ttatctaact cttttacttt ttcgtggtct
    53521 ccttcaaata agcttaaaaa acttgcttga gtaccagtag tacctttaac tcctcttaac
    53581 ttcatgttgt ctattctata gtttaaatct tccaaatcaa gaattaaatc ttgagtccat
    53641 aaacaagctc tttttcctac tgttgtaagt tgagcagctt ggaagtgtgt aaatccaaga
    53701 gctggcatat ctttgtactt aagtgcaaat tcttttaaat tgtttattaa atttacaagc
    53761 tttactctta gaagttttaa agcttcattc atttgtataa catctgtatt atctccaaca
    53821 tatgcagatg ttgctcctaa atgtattatt cctttggctt tttcacattg taaaccataa
    53881 gcttttacgt gagacattac atcatgtctt acttcttttt ctatttttct agcttcatca
    53941 aaatttatat tatctatatt agctcttagt tcatctaatt gttcttcagt tatattgatt
    54001 cctaactcat gttcaccttc tgcaagtgca acccataacc ttctccatgt agagaattta
    54061 aattgtggag aaaatatata actcatgtcc ttgctacaat atctgtctgt aagtggattt
    54121 gagtaagtag tatatttatt atctatcatt atattagcac cttccttaaa tcttttgtcg
    54181 tgtgattact gtgtacacat tagtacataa ataattatat ataattttac gaactataac
    54241 aagacttttt tattttttgt tcacatttat atatagtatt ttttatttat tactattttt
    54301 tatttatatc caaattatct ttttcaatta agtaatccac tatttcacta tcaacaaaat
    54361 ttaatacata cttatatcta attgcatagt atttatcact ccatccaagc tgatttttta
    54421 catcactttc atctgcccca agccttaaac ttattgctgc aaatgaatgt ctaaaatctc
    54481 ttgctgaata ttgagaaagt ccagctaaat ctaatgcttt tttgactata agtctgacat
    54541 ttctatctgt tatagaatta ctcttttgag ttgtaaaaat aaaatcatca ctaggtatta
    54601 ttacctctgg aagcccagaa taattcctgt aatcttctaa aagtttaaaa aagtatggat
    54661 gtaatttaac tactctttct tttcttccct tacctaacct tacatatgag ttatcgtttt
    54721 catctaccat aaggtctttc cactttaagc taactaattc atttaataaa cacccagtag
    54781 taactagaca gactattatt actctatctc ttatatttaa ttttggtagg atacctataa
    54841 gtttatttat ttcttgtata cttagaacat catcttttgt ttttattctt gttactgtgg
    54901 gtttttctac atatctaaat ggatttatat ctatgtatcc ttcttttttt aagaagttat
    54961 aaaaactatg taaataacta tatatctttt cacaagttga tttcgcatat ttagtctgta
    55021 tatagtctac aaaattttta caatcttctt tcgtagcata aatcaattct ttccctttta
    55081 aaaattcttt aaacagtata acctttgata aataatcgtg tttcgtgttt ggatttaatt
    55141 ttgtagaaaa aacattaaaa gtttcatact cataatcatc tagtattttt gtactataca
    55201 taataactcc tttccttttc ataaaataaa atagctatac ttttactata ccatatattt
    55261 ccccctcaaa tatacccctt attcaataga taacttttaa gtttattttg ttatattatg
    55321 aaggttttat gaaaatatca atcttccatt gtgcactaca cagtactatg gtattataag
    55381 ttagtaaaag gtggcatttt tttattaatc tatgaataaa atatgctact ataaatttgt
    55441 attggaggta ttttgatttg gaaacattta gtttgcttga aatttttaag gcagtcattt
    55501 tgggcatagt tcagggaata acagaatggc taccagtaag tagtacaggg catatgatat
    55561 tagttgatga gtttataaaa ttgaattttt caaatacatt tataagtaca tttttagttg
    55621 taattcaatt tggttcaata ttagctgtac ttgttatatt ttttagaaaa ttaaatcctt
    55681 ttgatagcgc aaagaatatt aagcagaaaa aagaaacagt ccgtttatgg cttaaggtta
    55741 taattgcagt tataccatct ggagttattg gaatactgtt tgaagatgat atagatagat
    55801 tattctttaa ttcaacagta gttgctattg ctcttattgt atatggtata ataatgatag
    55861 ggcttgaaaa gagaaataaa aaacctaagt ataaagattt ttctcaagtt acatataaat
    55921 tagctctttg tataggatta ttccagtgtc tagctcttat accaggtaca tctaggtctg
    55981 gttctactat aataggtgca gtattacttg gtacttctag atatgtagca gcagagtttt
    56041 cattcttctt agccatccct acaatgcttg gagctagtgc attaaaactt ctaaaagctg
    56101 gatttggatt tactggattt gaatggctta ttttaggtgt tggttctgta gtagcatttg
    56161 ttgtttcaat tgtagttatt aaatttttta tggactatat caaaaaacat gacttcaaag
    56221 tatttggtta ttatagaata gtcttgggta tagtggttct tgcttatttc tttctattat
    56281 aatgtattct aatttaataa caaatgataa ggagaaaagt tatgagtgtt aaaaaagaaa
    56341 tatttgattg gattaagtca atagctatgg ctattgtact tgcatttgta attctacaat
    56401 ttataagacc ttctattgta agtggagaat caatgtatcc tactttagat gataaagatt
    56461 atctgatttt aaataggata tcatacaagg ttggtaaacc tgaaaaaggc gatattgtag
    56521 tttttaaaac caatttagtt gatggagaaa caggaaagaa aaaagactta ataaaaagag
    56581 ttatagctac tgaaggtgac agaataaaaa tatcaaattc taaagtgtat gtaaatggaa
    56641 aattattaaa tgaaccatat atacacaata actatacttc tggagatata gatactgttg
    56701 ttccaaaagg taaactattt gcaatgggag ataatagaga aaatagtaat gatagtagat
    56761 tccctgatgt aggtatggtt gatgaaaatg aagttcttgg taaggttatg gtgagactat
    56821 tacctcttga taatattggg aaagtagact aaaaaataag agactgaatt ggtaaagttt
    56881 attttacaaa tctcagtctc tttttatttt cttaaattac aaatattttt ttactaaata
    56941 tcttttgatt ctgtaataag tcttattata tcacttgctt cttcattaaa agttgttact
    57001 atacttaggt agtctgttgc tctactcata gctaaataaa ccttatttaa atctcctaca
    57061 aagtcattta cttgataatc ttgttcaata tcatttatag tttgattata taacatctct
    57121 aattcacata ctattaccgc tttatactct aaattcttta ttgcatatat atttgctatt
    57181 gtagttccta ccttcttact tatatttgtc aaattatctt ctgcacatat ataaggaatt
    57241 tttgcctctt ccaatgcttt ttttaacata tattgaaagt aaatggtttt tccacttttt
    57301 aatttcttct tattgtaagg gtaaacgata gcaacttcag aataatcaag acctttttta
    57361 cttattaaat actcaatttc ccagattaca gaacttattt ggtcatcaag gtcacttact
    57421 tttattatat caacagactt atttccacct ctaagtgctt tagtataaaa gaaagtacta
    57481 aattctgtat ttggtcttaa ttcgtttata tatgagttag aattatttga aaatttattt
    57541 gtaaaatcta caatctcttt agcttgtcta taatttttac ttaagataat cttatcatca
    57601 aattctatac cattatataa ttttttaaat atattcaatc tattagagat attcaaggag
    57661 ttacaagaac atacattaaa tatgaatttt gttttatata aaaactccct tataaaatct
    57721 atttcatact ctaaaaagct ttctgcttca tcaataaaaa tagccttgaa catattttta
    57781 ttttttataa tgttctgtgc ttgttttaca agattattaa aggtcttttc gtaatcattt
    57841 tttaacatat tataatctac aattaaattg aattttttag ctagtttaaa tataaaagaa
    57901 ctaaatgtgt gaacttctaa attgttatta tctttgtata ataactctat cctttctcga
    57961 agctcattgc acaattgttt tgtatgtgta aatatgacta atttatgatg tggatatact
    58021 tttgctaatt ttatagccct agaaagcata attgctgttt tgcctatacc agaaccacct
    58081 tcaataagtg tattcccata tttaatagaa acaacatctt taatttgaac gtcttccatc
    58141 atagttgctg tatacttata gtcatcattg tagaatgaaa tttttttaaa tttttcattt
    58201 agatgaagtt tatcatttat tatatagtat tctgaacata tatctagtaa aaataaattt
    58261 aagtttattt catcattctc atcattaaga tattcctcca gcgaaccctt attcattata
    58321 tcttgaagct tatttttatc tattatatta ttattaacaa attcttcaaa ttcatatgtt
    58381 tcctcaactt caacgtatgg cataatgtaa acgtagttat aacttatatt tctattcttt
    58441 tgtcccattt ttagtttcaa aagttcatat tcctcattca taacttcaag taactcttct
    58501 tctaaaataa aaaatatatc ttctgttgta tccataaatt ttataaataa aattcttcca
    58561 tctttaacat acaacaaatc ggtatttatt cctttaaaag gagtaacttt tggcactact
    58621 ttaacgtcct cattgatatt ttcgtaaaat attttctcga actccttcaa ttttagggcg
    58681 tctaactgag aatttatatt tatgtattgg ctcacttaca ttacctcctt ctgttatact
    58741 taattatacc attttgaact atatttttat atatactttt tataggcaaa tttagtaaat
    58801 aaattcaaaa taaatacaaa taaatacaaa actgctaaaa taattttgca ata
//
LOCUS       DAEOTL010000015        55378 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEOTL010000015 DAEOTL010000000
VERSION     DAEOTL010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 55378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55378
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.015"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            983..1822
                     /locus_tag="KRH82_001240"
     CDS             983..1822
                     /locus_tag="KRH82_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBG8654530.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            1819..3000
                     /locus_tag="KRH82_001241"
     CDS             1819..3000
                     /locus_tag="KRH82_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654531.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            3304..4206
                     /gene="ptb"
                     /locus_tag="KRH82_001242"
     CDS             3304..4206
                     /gene="ptb"
                     /locus_tag="KRH82_001242"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBG8654532.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            4228..5307
                     /gene="buk"
                     /locus_tag="KRH82_001243"
     CDS             4228..5307
                     /gene="buk"
                     /locus_tag="KRH82_001243"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBG8654533.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            5297..5974
                     /locus_tag="KRH82_001244"
     CDS             5297..5974
                     /locus_tag="KRH82_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8654534.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6017..6232
                     /locus_tag="KRH82_001245"
     CDS             6017..6232
                     /locus_tag="KRH82_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8654535.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            6261..7340
                     /locus_tag="KRH82_001246"
     CDS             6261..7340
                     /locus_tag="KRH82_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBG8654536.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            7340..8092
                     /locus_tag="KRH82_001247"
     CDS             7340..8092
                     /locus_tag="KRH82_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBG8654537.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            8093..8650
                     /locus_tag="KRH82_001248"
     CDS             8093..8650
                     /locus_tag="KRH82_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBG8654538.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            8820..10166
                     /locus_tag="KRH82_001249"
     CDS             8820..10166
                     /locus_tag="KRH82_001249"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBG8654539.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSLPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATDLANLIQEKLS"
     gene            10433..12265
                     /gene="glmS"
                     /locus_tag="KRH82_001250"
     CDS             10433..12265
                     /gene="glmS"
                     /locus_tag="KRH82_001250"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBG8654540.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            12717..14012
                     /locus_tag="KRH82_001251"
     CDS             12717..14012
                     /locus_tag="KRH82_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBG8654541.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVRRGGHIKGAVDFSANWLSVYLDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            14468..15205
                     /locus_tag="KRH82_001252"
     CDS             14468..15205
                     /locus_tag="KRH82_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBG8654542.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            15226..16479
                     /gene="murA"
                     /locus_tag="KRH82_001253"
     CDS             15226..16479
                     /gene="murA"
                     /locus_tag="KRH82_001253"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBG8654543.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            16566..17630
                     /gene="spoIID"
                     /locus_tag="KRH82_001254"
     CDS             16566..17630
                     /gene="spoIID"
                     /locus_tag="KRH82_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBG8654544.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            17696..18364
                     /locus_tag="KRH82_001255"
     CDS             17696..18364
                     /locus_tag="KRH82_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBG8654545.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            18462..18722
                     /gene="spoIIID"
                     /locus_tag="KRH82_001256"
     CDS             18462..18722
                     /gene="spoIIID"
                     /locus_tag="KRH82_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBG8654546.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKENKKM"
     gene            18919..19938
                     /locus_tag="KRH82_001257"
     CDS             18919..19938
                     /locus_tag="KRH82_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBG8654547.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            19954..20382
                     /gene="fabZ"
                     /locus_tag="KRH82_001258"
     CDS             19954..20382
                     /gene="fabZ"
                     /locus_tag="KRH82_001258"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBG8654548.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(20493..21002)
                     /gene="yyaC"
                     /locus_tag="KRH82_001259"
     CDS             complement(20493..21002)
                     /gene="yyaC"
                     /locus_tag="KRH82_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBG8654549.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      21191..21294
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            21431..22624
                     /locus_tag="KRH82_001260"
     CDS             21431..22624
                     /locus_tag="KRH82_001260"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBG8654550.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            22940..24037
                     /locus_tag="KRH82_001261"
     CDS             22940..24037
                     /locus_tag="KRH82_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654551.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            24301..26520
                     /locus_tag="KRH82_001262"
     CDS             24301..26520
                     /locus_tag="KRH82_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBG8654552.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDT
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEILKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVEKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            26523..27305
                     /locus_tag="KRH82_001263"
     CDS             26523..27305
                     /locus_tag="KRH82_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBG8654553.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            27637..29550
                     /locus_tag="KRH82_001264"
     CDS             27637..29550
                     /locus_tag="KRH82_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8654554.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            29691..29999
                     /locus_tag="KRH82_001265"
     CDS             29691..29999
                     /locus_tag="KRH82_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8654555.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30022..30348
                     /locus_tag="KRH82_001266"
     CDS             30022..30348
                     /locus_tag="KRH82_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654556.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            30387..31721
                     /gene="celB"
                     /locus_tag="KRH82_001267"
     CDS             30387..31721
                     /gene="celB"
                     /locus_tag="KRH82_001267"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBG8654557.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            31732..32250
                     /locus_tag="KRH82_001268"
     CDS             31732..32250
                     /locus_tag="KRH82_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBG8654558.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            32346..33305
                     /locus_tag="KRH82_001269"
     CDS             32346..33305
                     /locus_tag="KRH82_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBG8654559.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            33354..34406
                     /locus_tag="KRH82_001270"
     CDS             33354..34406
                     /locus_tag="KRH82_001270"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBG8654560.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            34409..35083
                     /locus_tag="KRH82_001271"
     CDS             34409..35083
                     /locus_tag="KRH82_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBG8654561.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNSIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            35636..36187
                     /gene="raiA"
                     /locus_tag="KRH82_001272"
     CDS             35636..36187
                     /gene="raiA"
                     /locus_tag="KRH82_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBG8654562.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            36319..38994
                     /gene="secA"
                     /locus_tag="KRH82_001273"
     CDS             36319..38994
                     /gene="secA"
                     /locus_tag="KRH82_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBG8654563.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39009..40116
                     /gene="prfB"
                     /locus_tag="KRH82_001274"
     CDS             join(39009..39083,39085..40116)
                     /gene="prfB"
                     /locus_tag="KRH82_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBG8654564.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            40260..42401
                     /locus_tag="KRH82_001275"
     CDS             40260..42401
                     /locus_tag="KRH82_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBG8654565.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            42549..43715
                     /locus_tag="KRH82_001276"
     CDS             42549..43715
                     /locus_tag="KRH82_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8654566.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      43775..43892
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44017..44622
                     /locus_tag="KRH82_001277"
     CDS             44017..44622
                     /locus_tag="KRH82_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBG8654567.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            44951..45991
                     /locus_tag="KRH82_001278"
     CDS             44951..45991
                     /locus_tag="KRH82_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBG8654568.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            46130..46582
                     /gene="tsaE"
                     /locus_tag="KRH82_001279"
     CDS             46130..46582
                     /gene="tsaE"
                     /locus_tag="KRH82_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBG8654569.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            46582..47298
                     /gene="tsaB"
                     /locus_tag="KRH82_001280"
     CDS             46582..47298
                     /gene="tsaB"
                     /locus_tag="KRH82_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBG8654570.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVDFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            47288..47764
                     /gene="rimI"
                     /locus_tag="KRH82_001281"
     CDS             47288..47764
                     /gene="rimI"
                     /locus_tag="KRH82_001281"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBG8654571.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            47770..48786
                     /gene="tsaD"
                     /locus_tag="KRH82_001282"
     CDS             47770..48786
                     /gene="tsaD"
                     /locus_tag="KRH82_001282"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBG8654572.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49083..51791
                     /gene="hpdB"
                     /locus_tag="KRH82_001283"
     CDS             49083..51791
                     /gene="hpdB"
                     /locus_tag="KRH82_001283"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBG8654573.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEIKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            51795..52052
                     /gene="hpdC"
                     /locus_tag="KRH82_001284"
     CDS             51795..52052
                     /gene="hpdC"
                     /locus_tag="KRH82_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBG8654574.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52045..52995
                     /gene="hpdA"
                     /locus_tag="KRH82_001285"
     CDS             52045..52995
                     /gene="hpdA"
                     /locus_tag="KRH82_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBG8654575.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNVHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWTQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            53310..54272
                     /locus_tag="KRH82_001286"
     CDS             53310..54272
                     /locus_tag="KRH82_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8654576.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(54371..55351)
                     /locus_tag="KRH82_001287"
     CDS             complement(54371..55351)
                     /locus_tag="KRH82_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8654577.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFDLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILIFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22322 a         5850 c        10430 g        16776 t
ORIGIN      
        1 taagaaaagt ttactataaa ttatagtaaa cttttatatt gtttaaaaag acacaggaaa
       61 catgtatatt acctgtgtct ttttatttat aaactttaaa ctatgtaaaa attacagtat
      121 attctaatag agttacagta tattcattaa tattgtaaac atacggaggg taatgtataa
      181 tagtctacaa gatgtttatg aaggcatcag ttaaatataa taaatataac taattagtaa
      241 gagttatata cattatattg tatactttat ggtatttata tattgaaata acttatgaag
      301 ttatttataa agagattcat gagcatattt ttgtctaaac aataagtata agaaattata
      361 aaaaattaga gactatagtg aatttacaat ttaatgtaat atttataagt tatactaaat
      421 aaattattat actgtgaaat ggatatataa ctttaggtat tgtgtattat tttcactgta
      481 ggagattata tctagttata cataataagt tttaatgata gtttatagta agatattaaa
      541 ataaatttat ctaatctaga tatgaaataa gttattactt taatataaaa atgaatctaa
      601 tggaataata ttgatgataa gtaatattta gattttgtat ttgtttatag ttaataagtg
      661 gattatagaa tttataataa ttaatatata ttaaacaaag atatattaag atattttaga
      721 acacaaaact gcattaaggc gcgagtacta ttttgtattc gcgccttgat ggtttgagtt
      781 atttgagtaa aaactaactt taataagaaa tctgtattta ttaagttgat atttttaatg
      841 tatttagaga ttatttaaca atctccaaat ataaaactag aattatttac ataaaagtta
      901 aatagtttgt atagagttag atttatatag tataatactt agtgtaaata attaagaagt
      961 tatcaaacag gaggataaaa ctgtgttaga tataaattct tttttaaatg gattttttaa
     1021 tataatatta agaatgagta tatatgattt aattgacata tctatagtag cgtatatttt
     1081 ttacaaaata tttatgttta taaaagatac aagagcagaa caagtgttta aaggtataat
     1141 atttctttta ttagcaactc aacttagtaa cacctttaaa ttgcataccg tttattggat
     1201 atctcttaaa gctttagatt atggagttat agctgctctt ataatttttc aaccagaatt
     1261 tagagcagga cttgaacata taggaagagc aaagtttaat ttatttggaa agaatgtaaa
     1321 tacttctgaa gaaactctca atagaaatat agaagaaatt gtagaagctt tatattcact
     1381 ttctagacaa aaaataggag ctcttatcat aatggagaga gaaactagaa taagtgatat
     1441 aataaataca ggaactatta ttgatgctga aatttctagg caactattaa taaatatatt
     1501 tataccaaat acaccattac acgatggagc tgttgtaatt agagattcta aggtaaaagc
     1561 agctgcatgt tttttgccat tgacagaaag taaggattta agtaaagatt tgggtactag
     1621 acatagagca ggaatagggg taagtgaggt gtctgactgt ataactttga ttgtatcaga
     1681 ggaaacaggt ggcgtatcaa ttgctaaagc aggtaagtta tatagagata tttctagaga
     1741 aagaatgatg aatatattac gtagtaattt aaaaacaaat acagaaacaa gaagtttttt
     1801 caaaggtggt atatttaaat gataaataga ctaaaaaata ataccaaaat aaaaataata
     1861 tcatttttaa gtgcaattgc attatggatg tatgttatgg ctgtagttga ccctgaagaa
     1921 actaaagggt ttgaagatat acctgtatct ataagtaata tgagtgattt aaaggataaa
     1981 aatcttgtta tatatccaga cgaaaaatta acagcagatg tatatataaa aggtagttta
     2041 tcaaaggtac aaagtgttaa aaaagaagat atacatgtat atggaaccat tgaagaccca
     2101 atacaaggac agaaggaagt atatttaaaa gcaaatattc ctcaaggtgt tactctagaa
     2161 tttaagcatg atgttttagt agtaaatctt gaaaaaaaca taaaagaaaa aagagatata
     2221 aaggtagaag taagtggaaa ttcaaaaaga aatataaata aaattgaact tagtaaggaa
     2281 tttgtcgatg tatcaggtcc aagaactcta gttaaagaag tcaaaagtgt aagagctaat
     2341 ctagatgttg gtaatgagac agatgatttt tctaaaaaat tgcaattaat accattaaat
     2401 agtgatggaa ctaaggttga aggagtaaca ttaagttcat cctttgtgac tgcaaagata
     2461 gaactattga aggaaaaaat tgtcccaata agagtaagtc taaatgataa taaagataat
     2521 gatgtactga aaaactataa attaagtaag gaacaagtta caataaaagg aaagaaagaa
     2581 gatatagaca aaataagtta tattaagaca aaacctattg acttagctga tttggctaat
     2641 ggtgaagaaa aagaagttag cttagaaatt ccagagggta taactcttga ggatagctct
     2701 ataacaatta aattaaatga tacaaaacaa ttgagtgcag aatttttata taatgcggga
     2761 gatattgaat taagaaatat cccaacaaat atggataatc caaatgtaat ttctgatgta
     2821 gatataaaag ttgttgtaga gtcaacggag gatttgagta agttaaataa aaaagatatt
     2881 tcattatata ttgatttatc acaaggccct gaggaagata gtaaatataa aataaaatat
     2941 gaaacaacat atcaatttaa aaaaataaat atagaaccta atattgttga agtggaatga
     3001 acaaatattt cgaatattta gttgttacaa gatgcgacaa aaaaacctat aaaattaagt
     3061 ttgttaattt tatgtttttg ttgcatcttg tttattttag ttatattata aaataaggac
     3121 aatgagatat ttgttaaatc taaaaagcgc tagatatatg aaaaaagact gataaataga
     3181 tttaaataaa tattttgaat taaatatttc aattatctct aggaaaacgt tgctgaacga
     3241 gttataattt aattgagata taaaaagttc tatttcaaaa aattcaagat gaggtggaaa
     3301 tgcatgagaa gttttgaaga agtaattaag tttgcaaaag aaagaggacc taaaactata
     3361 tcagtagcat gttgccaaga taaagaagtt ttaatggcag ttgaaatggc tagaaaagaa
     3421 aaaatagcaa atgccatttt agtaggagat atagaaaaga ctaaagaaat tgcaaaaagc
     3481 atagacatgg atatcgaaaa ttatgaactg atagatataa aagatttagc agaagcatct
     3541 ctaaaatctg ttgaattagt ttcacaagga aaagccgaca tggtaatgaa aggcttagta
     3601 gacacatcaa taatactaaa agcagtttta aataaagaag taggtcttag aactggaaat
     3661 gtattaagtc acgtagcagt atttgatgta gagggatatg atagattatt tttcgtaact
     3721 gacgcagcta tgaacttagc tcctgataca aatactaaaa agcaaatcat agaaaatgct
     3781 tgcacagtag cacattcatt agatataagt gaaccaaaag ttgctgcaat atgcgcaaaa
     3841 gaaaaagtaa atccaaaaat gaaagataca gttgaagcta aagaactaga agaaatgtat
     3901 gaaagaggag aaatcaaagg ttgtatggtt ggtggacctt ttgcaattga taatgcagta
     3961 tctttagaag cagctaaaca taaaggtata aatcatcctg tagcaggaag agctgatata
     4021 ttattagccc cagatattga aggtggtaac atattatata aagctttggt attcttctca
     4081 aaatcaaaaa atgcaggagt tatagttggg gctaaagcac caataatatt aacttctaga
     4141 gcagacagtg aagaaactaa actaaactca atagctttag gtgttttaat ggcagcaaag
     4201 gcataatttt aagggggaaa taggcaaatg agcaaaatat ttaaaatctt aacaataaat
     4261 cctggttcga catcaactaa aatagctgta tttgataatg aggatttagt atttgaaaaa
     4321 actttaagac attcttcaga agaaatagga aaatatgaga aggtgtctga ccaatttgaa
     4381 tttcgtaaac aagtaataga agaagctcta aaagaaggtg gagtaaaaac atctgaatta
     4441 gatgctgtag taggtagagg aggacttctt aaacctataa aaggtggtac ttattcagta
     4501 agtgctgcta tgattgaaga tttaaaagtg ggagttttag gagaacacgc ttcaaaccta
     4561 ggtggaataa tagcaaaaca aataggtgaa gaagtaaatg ttccttcata catagtagac
     4621 cctgttgttg tagatgaatt agaagatgtt gctagaattt ctggtatgcc tgaaataagt
     4681 agagcaagtg tagtacatgc tttaaatcaa aaggcaatag caagaagata tgctagagaa
     4741 ataaacaaga aatatgaaga tataaatctt atagttgcac acatgggtgg aggagtttct
     4801 gttggagctc ataaaaatgg taaaatagta gatgttgcaa acgcattaga tggagaagga
     4861 cctttctctc cagaaagaag tggtggacta ccagtaggtg cattagtaaa aatgtgcttt
     4921 agtggaaaat atactcaaga tgaaattaaa aagaaaataa aaggtaatgg cggactagtt
     4981 gcatacttaa acactaatga tgctagagaa gttgaagaaa gaattgaagc tggtgatgaa
     5041 aaagctaaat tagtatatga agctatggca tatcaaatct ctaaagaaat aggagctagt
     5101 gctgcagttc ttaagggaga tgtaaaagca atattattaa ctggtggaat cgcatattca
     5161 aaaatgttta cagaaatgat tgcagataga gttaaattta tagcagatgt aaaagtttat
     5221 ccaggtgaag atgaaatgat tgcattagct caaggtggac ttagagtttt aactggtgaa
     5281 gaagaggctc aagtttatga taactaatga taaaagaata agaatcataa ctggtcacta
     5341 tggaagtggt aaaagtgaat ttgcgatgaa ctatgttgtt aagttaagag atatggtttc
     5401 tggcaaagtt gctatagccg atttagatgt ggtaaatgta tactttagaa ctagagaaaa
     5461 gaaagagtta atgaaatcct taggtataca accaatagat agctcaatta atgctccaac
     5521 attagattta ccagcagtat cagcagaggt aatgtctcct atggtagacc attcatacaa
     5581 ttctgttata gatttaggtg gagataatgt aggtgctagg gttataggaa gatttagtca
     5641 tttgttaaaa gaaggcgatt atgatatgct ttttgtaata aatgcaaata gggagaaaac
     5701 tcaaacttct gaagaagtta tccaatatat aaaagaaata gaaaaatctt ctaaattaaa
     5761 ggtaacaggt ctaattaata atactcatct tattaggttt actactattg atgatgtttt
     5821 aagaggtcag aaagttgcaa aagaagtttc tgaaaaatgt aatataccga taagatatgt
     5881 tgcatgttta gaaaatcttg ttgaacagtt accaaaagat ttagaaggag aaatttttcc
     5941 tataaaatta tatatgagag aagactggat gtagtttgag ctcaaatata tagaaagttt
     6001 aaggaggctt aggtaaatgg ctaaaggaaa agtatctttt aatcaagaac gttgtaaagg
     6061 ttgtggattg tgtgttgaag catgtccagt aaaaatcata caattagact caaatgtaat
     6121 aaacaaaaaa gggtataacc cagcaactgt ttttgaaatg gaaaaatgca taggatgtgc
     6181 aagttgtgca actatgtgtc cagatgtagt tataacagta gaaagagatt aatttaatta
     6241 atatttaagg gggaatttta atggctaaga tacttatgaa aggtaacgaa gcatttggaa
     6301 aagcagctat agaagctggt tgcaaatatt tcttcggtta cccaataact ccacaaagtg
     6361 aattaccaga atatttatca agagagttac ctaaaatagg tggagcgttc gttcaagctg
     6421 aatcagaagt ttctgcgata aacatggttt atggtggagc aggtgcagga gcaagagtta
     6481 tgacttcttc atcttcacca ggagttgctt taaagcaaga aggtataaca tatgcagtag
     6541 gagcagaagt tccttgtgtt gtacttaatg taatgagagg tggtccagga cttggaagta
     6601 tacaaccttc acaagctgac tactttatgt ctacaagagg tggaggaaat ggagactaca
     6661 gaactccagt attcgcacca gctacagttc aagaagctgt tgatatgata atggaagctt
     6721 ttgacgttgc agattattac agatcaccag ttatggtagt tgcagatggt atgataggtc
     6781 aaatgatgga gccagttgaa tttagagctc ctgagaagaa aagagaattg cctcctaaag
     6841 attgggcaac tgttggaact aaaggaaaaa gaaaacctaa tgtaataaac tctctatact
     6901 tagagccaga agtactagaa gaccattgtt ggcatttaca agaaaaattt gatgcaatgg
     6961 aaaagaatga agtacaatac gaaatgtaca aaacagaaga tgctgaattt gtatttgcag
     7021 cttatggaac tacttcaaga gtagtaaaaa gcgcaattga tatattaaga gaagaaggaa
     7081 taaaagcagg tcttataaga cctaaagtat tatggccatt cccattcgaa gcattcaacc
     7141 aaattcctaa tgctagaaac atattgactg ttgaaatgag tatgggacaa atggtggaag
     7201 atgttaaaat ggcagtagaa ggtaaattac cagtttactt ccatggaaga ccaggaggaa
     7261 tgactccaac accagcagaa atagttgaaa aagctaaaaa aattattgcc ggagaattgg
     7321 ttgcaggagg tgctagataa tggctgttgt atttaagaaa actgaaggat tacaagatac
     7381 tcaaactcac tactgtccag gatgtacaca tggtataatc catagattag ttggtgaagt
     7441 attagaagaa ctaggagtat taggtgatgc tgtaggtgtt gttccagttg gatgttcagt
     7501 tttaggatat aaatatttta actgtgacac tcaagaagct gctcatggta gagcgccagc
     7561 tgctgctaca ggaataaaaa gagttcatcc tgaaaataca gtattcactt atcaaggtga
     7621 tggagactta gcttcaattg gtactgctga aatagttcat gcagctgcta gaggagaaaa
     7681 aataactact atatttgtaa acaatacaac ttatggtatg actggtggac aaatggctcc
     7741 aactacatta gttggacaaa gagctactac tgctcaatca ggaagaaatg ctgaaactca
     7801 aggttatcca ataagagtaa gtgaaatgtt agctacatta acaggagctg tatttgtaga
     7861 aagagtagca gttgatactc cagctcatgt tagacaagct aaaaaagcta taaagaaagc
     7921 attccaagtt caacaagcag gattaggatt tggaatagta gaagtattat ctacttgtcc
     7981 tacaaactgg ggactagctc caaacgatgc tttacaatgg ttaagagaca acatgatacc
     8041 atactatcca ttaggaaatt tcaaaaatgt tgaagttgag gaggtgaagt aaatgtctac
     8101 agctagagta atatgtgcag gcttcggagg ccaaggtgtt atgtctatgg gacaattact
     8161 tacttatgca ggaatgctag aaggaaaaga agtttcttgg ttaccatctt atggaccaga
     8221 aatgcgtgga ggtacagcaa actgtgcagt aactgtatct aatgagccag ttggttctcc
     8281 acttataaca gatgatgcaa ctgcagctat attattaaat ataccagcat ttgaaaaatt
     8341 caaagatgat gttattcctg gtggaaaaat aatagtaaat agttctttaa taaaagaaaa
     8401 agttgataga acagatgtag atgtttatta tataccagca aatgaattag cagctgaatt
     8461 aggaaatgat aaagttgcta acatgataat gttaggcgct tacttaaaag tatctgatac
     8521 tgtagatata gaatctgtac tagaagcatt caaaaaagtt ttcggaccta gaaaagaaaa
     8581 attcgttcca ttaaacagag aagctttaca aaaaggtatg gatgctacat gttctaaagc
     8641 aactaactaa taaagaaaaa gatgtcaaaa aaaagacaat agaattattt ctattgtctt
     8701 ttttgctgat aagtattaaa atatttttat gactgaaatt aagcctataa tgatatttta
     8761 tgaactataa aaatataata caaattacaa gcttttcaat tatgaaagga gaatctttag
     8821 tgagaaagta ttttggaaca gatggagtta gaggagtagc aaatacagaa ctaacatgtg
     8881 atttagcata taaacttggt agagctggtg gatttgtctt agctcaagga gaccacagag
     8941 taaaagtagt agtaggtaag gatactagaa tatcaggtga tatgttggaa gcatctttaa
     9001 tagcaggact tatgtctgtt ggatgtgatg ttattactgt tggaataata ccaacacctg
     9061 cagtggcata tttaactaga aaatatggtg ctgattgtgg tgtggttata tctgcatctc
     9121 acaatcctgt tgaatataat ggaatcaaat tctttaataa gaatggatat aaattagatg
     9181 atgaaattga attgaaaata gaagaatata tagacgatat agacaaaatt gattgtcttc
     9241 caattggtga aaatgtagga agaaaattac atgaacattg tgcacaaaga gactatgtag
     9301 actacctaaa atcaataata agcactgact ttaagggatt aaaagtagtt ttggactgtg
     9361 ctaatggtgc gtcatataaa gtggcaccaa tagtgtttga tgaactagga gcaagtgtaa
     9421 tttcaataaa tagtttacca gatggaaata atataaacta taaatgtggc tctacacatc
     9481 cagaacaact tcaaagggct gttttggaac ataatgctga cttaggtctt gcatatgatg
     9541 gagatgctga tagattaatt gcagtaaatg aaaagggtca aattgttgat ggagaccata
     9601 taatgatatt gagtgcctta aatttaaaga aaaataataa attggcacaa gatactttgg
     9661 tagttacagt tatgagtaat atagggttga caatagctgc taaggaaaat ggaataaatt
     9721 tatctactac agcagttgga gacagatatg ttttagaaga tatggttaaa aatggatata
     9781 atcttggtgg agagcaatct ggacatatga tatttttaga ttacaacact actggagatg
     9841 gagtgcttag ttctctaata cttgcaaata taattttgca agaaaagaaa cctttatcag
     9901 aaattgcatc aataatgagc caatacccac aagtattagt aaatgcaaca ataaaaaatg
     9961 aaaataagaa caaatatatg gaatatccag aaataaaaac tgagatagaa agaatagaat
    10021 ctattttaga cggaaatggt agagttttga taagaccatc aggaactgag ccattagtta
    10081 gagttatgtt agagggtaaa gaggaaggtc aaataaaaga attagcaaca gacttagcta
    10141 atcttataca agaaaaatta tcgtaattta aagggtattc tcagatacaa atactgagga
    10201 cacctttcta agcgccagaa cttagttata gacataatta ttgagtaata taggaactaa
    10261 gttgacgagg tcagagttaa tcgaattgtc ggcggatgct ctgcggtgtg tttaccatcg
    10321 aaagacttct ttaaataata ggagcaatcc tatggacaaa gggaagccaa agtaaactta
    10381 tatgacctaa ctcttaaaat atataaataa tatttttagg aggacacaaa taatgtgtgg
    10441 aatagttgga tatttaggaa gtagaaaggc agcagaagtt atagtagaag ggctttctaa
    10501 gctagagtac agaggttatg actcagcagg agtagcagtt aatagttcta atgaaaaaga
    10561 acttaatatt agaaagttta aaggtagact ttctgtactt gcagaagact tagaaaagaa
    10621 tcctattgat ggaaatttag gtatagggca tacgagatgg gcaactcatg gagaaccatc
    10681 tgatgtaaac tcacatcctc attttaatca agccaaaaca atagcagttg ttcataatgg
    10741 gataatagaa aactatatgg aaataaaaga agaattaatt tctgaaggtg ttaagtttga
    10801 atctcaaaca gatacagagg taatagcaca tttagtagat aaatactatg agggtaattt
    10861 attagatgct gtatacaaaa ctatatcaaa attaagagga gcttatgcat taggtgttat
    10921 atgtaaagaa catggaaatg aattagttgc agtaagaaaa gatagtcctc ttgtagttgg
    10981 tgttggtgaa ggtgaaaact ttatagcatc agatatacct gcattattaa aatatactag
    11041 agatgtttat ttcttagaaa atggagaagt agttcatcta aaagacgaaa atgtaaccgt
    11101 ttatgactct aatagaaatc ttgttgaaaa agaagtattt catgtaactt gggatgtaga
    11161 agctgcgtct aaaggtggat atgactactt tatgtcaaaa gaaattcatg agcaaccaac
    11221 aggagttaga gaaactttag aaagaagact tgatgataat ggaaatataa ttctagacag
    11281 tataaatatt tctaaagaag acttagaaaa aataaataaa gtttatatag tggcttgtgg
    11341 aacagcatat aatgctggat tacttggtaa gtatgccata gaaaaatttg taaatatacc
    11401 agtaataact gatatagcat cagaatttag atatagcgac ccatttgtag atgaaaattc
    11461 attagtaata ttagttagtc aatctggtga gacagcagat actctagcag tattaagaga
    11521 ttcaaaggct aaaggagcaa gaatactttc aataactaac gttgtaggtt catctatagc
    11581 aagagaatca gatgatgtat tctatacttg ggcaggacct gaagtagcag ttgcatcaac
    11641 taaggcatat actactcaaa taacttcttt atacatgata gctttagact ttgctatcaa
    11701 aaaaggaaca ataactagag aattttatga tagtatgatt tctaagatga aagaaatacc
    11761 atcaaaaata caagaaatac tagacaatga agaatatata aaagaagttg ctaaaacagt
    11821 tgttagttct gaacatgcat tctatttagg aagaggtata gactatagct tagcaatgga
    11881 aggttcattg aaattaaaag agatttcata tatacatgca gaagcttttg cagcaggaga
    11941 gctaaagcat ggaacaatag ctttaataga aaaaggaact cctgtaattg ccatagctac
    12001 tcaagaaaag ttatttgaaa aaatggtttc taatatggaa gaagtaagag caagaggagc
    12061 ttatgtagta gcaatagctc aaagccataa taaggatgtt gagaaagctg ctgataaaat
    12121 aatctatata ccaaattcag atgatatttt atcaccaata ttagcagttg taccaatgca
    12181 attacttgct tatcatgtct ctgtactaag aggatgcgat gtagataagc caagaaatct
    12241 agctaaatca gtaacagttg aataaaaaca gattaaaaat taaatagata atatttattg
    12301 aaaagaactc atcctgttat ttgtatttta taggatgagt tttttagata aatattaaat
    12361 ttgttttgtt tttgctataa taaattttat aaaaagattg atattaaatc atctgtaaaa
    12421 tgataaatat atagaccata ccaggtatag ggaacgataa atatagttca tataaaatat
    12481 agtgagtact taataaacat atagtcaata tcagataaaa aaaataatag cttatgagaa
    12541 aaattaaaat acaaggtatt agtaaccttg tgataagata aagtgagtag tttaaaataa
    12601 gaatataagg aactatttat aaaagaatat aatgaagcta atagagtata agaaaattac
    12661 tttattttag taaaataatt tcaaataaaa atttttttaa attgggagta taaattatga
    12721 caaatgattt taaaaaagaa aagaaagaag attattttgt taatcttaag gcaatatcta
    12781 ctgaagtttt acaagaaaaa gtgcaagata acgcttgggt tatagttgat actcgcttaa
    12841 atgatgctta taatggctgg aagttagatg gagtaagaag aggtggacat ataaaaggag
    12901 cagtagattt ttctgctaat tggttaagtg tatacttaga tagaaaagat gaagtgttag
    12961 aacaagcatt gaaaactaaa agaattgatt tagataaaaa tatagtattg tatgatgcaa
    13021 atggaaaaga tgctttggtt gtagcagatt atttatctaa aaaaggatat aaatatctat
    13081 ataaatatga tattaaacaa tgggcagacg acgaaaatct tccaatggaa agatataaaa
    13141 attatcaaat gatagttcct gcttttataa taaaagatat attagatgga aaaattcctg
    13201 agacatttga agattcaaag aatataaaaa tgattgaagc gagttgggga gaagaatcgt
    13261 atacaaaagg gcatatacct acaagtgttc atgtaaatac tgatattata gaacctcctc
    13321 caacatggat gcttgataat gatgataact taactaagtt tgctttagac tatggattaa
    13381 caaaggatga tactgtaata gtttcaagta gtacacctat ggcatcttat agactagctg
    13441 ttatattgag atatatagga gtaaaagatg taagagtttt gaatggtgga acaaactcat
    13501 ggttatcagc aggatatgaa ttagaattta ttagtaatcc aaaacattca tgtactaatt
    13561 ttggagcaga tataccagtt aactcacaat tagttgttac tacatctgaa ttaagacaaa
    13621 aactaaaaga aaaaaataag tttatactag tagataaccg tacttgggat gaacatatag
    13681 gaaaagtatc tggatataca tattatgata aaaaagggcg tataccagga gctttatatg
    13741 gacattcagg tagtgatagt gtttcactag aagaatatcg taatattgat aatacaatga
    13801 gaaataaata tgagatttta gaaatgtggg acaaggaaaa tatagatgtg aataaacagc
    13861 ttatatttat gtgtggaagt ggatggcgtg ctgctgaagt attaacatat gcaaatgtca
    13921 taggagtgga aaatacctcc ctttatagtg atggatggat gggctggagt cttgataatt
    13981 caaatttaat tgaagtggga gaacacaaat aaagtttttg aaagtacaat agagttgttt
    14041 aaaacaaagg tgtttttgat ttattaggaa gagtgtgtaa attgtgtatt gggaagtgta
    14101 cttaggtatg ttcatttgga gctatggaaa ttgataaaaa agtattatct gtttattttg
    14161 ttggtaaaat atgaatagat tatagattat agattataga ttatagatta tagatttaag
    14221 tatagactaa gtaatttata ttacagaaga gaatatataa gaattaatgc aagatgtatt
    14281 tgatacatat aagaaattgg caagtccagg agaaggatag agaaaattga gattgaagag
    14341 tttgaaagag attattagat gaaaaataca aaaatgtata aaaatacata ttgagaaagt
    14401 atatctctct taaatttgtt aataattcta ttatacagaa aaacatattt aagggggatt
    14461 ttttactatg aaaaaagtaa aattagctat aagctttttt atattaatga ttataggaat
    14521 gacaatatct tatgcagata caagtataaa tactagatac aatagattaa gtaaagctct
    14581 tgaaatatca gaagcaaatt ttaaatttta taatgttaaa attaattctg ttataaatca
    14641 taatttatca aataaagaat ttcataatat ttttatagaa ataattaaca atctaaagtt
    14701 ggataaaaaa ggaataaatt ggaatcaaaa agggtctggc gataaaatac aattatgtgc
    14761 tactataaaa ggtagcgata aagaaatttc tataaaagga ataaataaaa ataacaaaga
    14821 aagttacata gtagttgaca tattggataa caaagtatat aaacataaag aggttattta
    14881 tagtaacgta gaaaatgtgt taaataaata ttcatctcaa gtagatgtgt ctgcttgtat
    14941 tgttggagaa tacacaaaaa ggttacaaaa caacaaatat gatgatattt tacaaaaaat
    15001 attatataat atgagtgcta agcaaataga tgaagttaaa gacgtaaact ttttatctat
    15061 aacagcatat agtaaagtat taaatgatta tgaattagaa tatttagggg aaaaaattaa
    15121 tttaaatata ggaattaaat ataatgagga tgacggaaaa acactcatat atattgccac
    15181 accaattata aaattagatt attaattatg aggagatcaa aaaatatggc taagataata
    15241 gtaaaaaaga gtaatccact taaaggtagt gttaaaatag atggtgcaaa aaatgcagtt
    15301 ttaccaataa tagcagcgac tttattagca aacggaaaat caacattaaa tggagtacca
    15361 aatttaagag atgttcatgt tatatcagat ttattaagac atgtaggagc agaagttgaa
    15421 tataaagaaa atacacttac tgttgatgca agcaatataa aaacttgtga agctccatat
    15481 gagcttgtaa gaaagatgag agcttctttt ttggttatgg gaccattgct tgctagattt
    15541 aatagtacga aaatttctat gccaggagga tgtgctatag gaacaagacc tatagattta
    15601 catttaaaag gatttaaagc cttaggtgca aagatagaaa tggaccatgg ttttgttgaa
    15661 gcagcaacag aaaagttagt aggaaataaa ttatatttag atttcccatc tgttggagca
    15721 actgaaaaca taatgatggc agcttcttta gcagaaggga ctacaataat agagaatgca
    15781 gcagaagagc cagaaatagt agatttagca aacttcttga acgaaatggg agcagatgtt
    15841 aaaggtgcag gtactaatac tataaaaata aaaggtgtta aagagttaaa aggagcagaa
    15901 cataatgtaa ttccagacag aatagaagca gcaacttata tggttgcagc agctatgaca
    15961 aaaggtgata taactgttga aaatgtttta atggagcatt taaaaccagt tgtagctaaa
    16021 ttaagagaag ctggttgtga aataacagaa atggacaatt ctgtaagagt tgtaggtcca
    16081 aaagtattaa aaccaataga tataaaaact ttaccacatc caggatttcc tacagatgtt
    16141 caagcacaat ttatggctat gcttactgta gccaatggaa ctggtgtagt tatagaaact
    16201 gtttttgaaa atagatttat gcatgttgct gaatttaata gaatgggtgc taatataaaa
    16261 atagatggaa gaagtgcggt tgttaatggt gtagatgagc tacacggtgc agcagtaaac
    16321 gctactgatt taagagcagg ggcagccctt attttatgcg gtcttatagc agaaggagaa
    16381 actcaaatag gagaaatata ccatatccaa agaggttatg ttgatataga taagaagata
    16441 acagcactag gtggtcaaat cgaaatagta gaagattaat aattggttta tagaagaaag
    16501 ttataaatta atagggttgt tcatatactt aaatacaagg ttttaaaagc taaggaggag
    16561 agtatatgaa gaacccattg gttgttttgt taggatttgt gacttgctct gtgttagttc
    16621 catcacttat aactttagtt tcttataaaa atgtagaatt aactgaaaaa ccagagagcc
    16681 cagtatctat aaacaaaact attaaaaaaa gtgatattga agacaaaggt aataaagaag
    16741 aaaaaaatac agtgaactat gaaactgtaa ataaaaaagc accaattatc aatgtatata
    16801 atcatataac agggaaaacc gaaaagatgg acatggagaa ctatttatgt ggagtactag
    16861 ctggtgagat gtcttcagag tttgatatag aagctttaaa agctcaatct gtagcagcta
    16921 gaacatatgt agtatataaa caggaacatg gtaaatctag taaacataaa aatgcagtag
    16981 tatgtactga ttataaacat tgtcaagaat ataagagtta tgatactctt aaaaaattaa
    17041 atggtgaaga atggattaag aataaatatt ccaaaatcca agaagcagtt agaggaacta
    17101 aaggtcaaat aataacttat aatgataagg cgatacttcc tctttatttt tctacatctt
    17161 caggaaaaac agaaaatagt gaagaagtat tttctgcaaa atatccttat ttaaagtctg
    17221 tggaaagtcc ttatgataag tattccccta aatttgcgtc aacacttaaa ataagtaaca
    17281 cagattttgt taaaagtctt agaagggcat atagcactat tgtgatagat gtaaataatt
    17341 taagtaaaca agtttcaata actaaaagaa gtgatgccgg aactgtagaa aaaataaaat
    17401 taggaaataa agaattgact ggaaaagaca ttagaactgt ttttaaattg aactctgcaa
    17461 actttgacat aaaatttgga gaaggataca tagatttcgt ggtaaaagga tatggtcatg
    17521 gtgttggtat gagccagtgg ggagcagaag gaatggcaga agagggctat aaatattatg
    17581 atatattatc acattactac acagatacaa aaataaaaga tatatactaa taattgtata
    17641 aaatgccaaa aacacgtcaa taatccaaat gtagaaatat atttggaggt gcaaaatgaa
    17701 gaaaaagctg ttagaaaaag atggttttta tttatctttg tttgtatgtg tttgtttatt
    17761 agcagtaggt ggagtttggt ttacaaataa taatgtagat aaattggctt ctaataaagg
    17821 aattatggaa aatgctaata aagatagtga agaggaaata catttaattg aaaaagacaa
    17881 gaaagatgct atccctactg caacggattc aaaacaaaac ttagaaaaag ctaagtcaaa
    17941 agaggaaaat aaatcgagta caacaaaatt aaattacatt ggagataaag taataagagg
    18001 atattcagaa aaagagccta gttattctaa aacacttgat gtttgggaaa ctcataaagg
    18061 tgtagatatt agttgtacta aaggcaaaga agtaaaatct ctattaaacg gaatagtagt
    18121 agatgtattt gatgatgaag aatatggaca atcagtcaaa ataaaaagtg acaataacat
    18181 tgtagtagta tattcaaatc tagataaaaa tgttagtgtt aagaaagaac agaaggtaac
    18241 agaaggacaa tctctaggta ctgtaggtag tacttctcaa atagaaagtg aagaaggtat
    18301 acatgtgcat ttagaggcgt atagtggaga aaaatctata gacccaatga gtctaattaa
    18361 gtaatagtat aacaagttta atcatatttg gttaagcttg ttatattttt tggtgttttt
    18421 acatatatat cattaaagct attatgtgag gggggtaatc tttgagatct catatagagg
    18481 aaagggccat agtggtagca aaatatatac ttgaaaaaaa cactacagta agacaaaccg
    18541 ccaagacatt tggagtaagt aaaagtacaa ttcataagga tgttacagaa agattgaagg
    18601 aaataaatcc atcccttgcc aaagaagtta aaaatgtgct ggacaaaaat aaatcagaga
    18661 gacatattag agggggatta gcaacgaaat taaaatatga gaaggaaaat aaaaaaatgt
    18721 aggttaaaaa cctacttttt ttattgaatt aaattataaa aagaaatata ttaagtaatt
    18781 ataaatagca aaataataat actctcaaaa gatttatttt ctcttgatta aagcgagatt
    18841 tttgtatatg ctttattata ggagtattaa aataggctta taatataatc taatattata
    18901 aataaaggag ttgaaaaaat ggctggagct gatataggca tagatttagg tactgcaaat
    18961 gtgcttgttt atgttagtgg taagggaatc gttttagaag aaccatctgt tgtggcgata
    19021 gacaaaagaa cagattctgt tttagctgtg ggagaagaag ctaaaaagat gatagggaga
    19081 acaccaggta atatagtcgc tataagacct ttaagagatg gtgtaatttc agattatgat
    19141 gtaactgaga agatgttaaa atcttttata gataagatag ttgataaaaa gggatttgga
    19201 agatttttta tgccaagaat tatggtatgt gtaccaacag gtgtcacaga agtggaaaaa
    19261 agagcagtag aagatgctac gagacaagct ggagctagag aagtatatat catagaagaa
    19321 ccaatagcag ctgccatagg agctggtgta gacatatcac agcctaatgg taatatgatt
    19381 atagatattg gtggaggtac tgtagatata gctgtaatat ctctaggagg agctgttgta
    19441 agtgaatcta taaaggttgg tggagataga tttgatgatg ctatagttaa atatatgaaa
    19501 aaacaacaca atcttcttat aggagaaaga acagcagaga aaatcaagtt tgaaataggt
    19561 tctgcattta agagagaaga agaaaaatat atgaagataa caggaagaaa tttaattaca
    19621 ggacttccta gttctataac tataaattca acagaaatgt tggaagcact tagagaatgt
    19681 gttgagcaaa tagtagttgc tactcatgct gttttggaaa aaacgcctcc tgagttagca
    19741 gcagatatag gagatgtcgg tataataatg actggaggag gttcattatt atatggatta
    19801 gataaaataa tagaacagag gacaggaata actgttacaa tagcagatga accattatct
    19861 tgtgttgcaa aaggtacagg aatagcttta ggttcaatag acttacttga aactggtggg
    19921 tctttcaaaa gaaaataatt aggagagttt agaatgttaa atatagatga aataaaaaaa
    19981 ttaataccac atagatatcc atttttatta gtagacaaga ttacagagct agaagttggg
    20041 aaaagagctg ttggtataaa gaatgtaaca gttaatgagc catttttcca aggtcacttt
    20101 ccagaatatc ctttgatgcc aggagtacta atagtagaag ctctagcaca agtatgtgga
    20161 gtggcaatga tgtctgtaga ggaaaacaaa ggaaaactag gtgtatttgc aggtatagat
    20221 aaagttagaa tcaagagaga agtaagacca ggagatacat taactatgga agttgaaatg
    20281 acaactctta gaaaaaatat agctaaggca gatgctaagg catatgtagg tgaagaactt
    20341 gtctgtaaag gtgaattaat gtttgcttta gtagaaaaat aaaaacttga aatataaaag
    20401 taaaaaggta gataatttgg agtatttaat cagatactct aaaatatcta cctttttata
    20461 taaagaattt tatcatttag tttatattta gattaggtgg atactaataa agccaaggct
    20521 attgtttcag ctaaatctaa tataaagcta aggcgtatat tattaaatga aagtttatta
    20581 ttttcatcaa ttttatctac aattcctact atagaataat ttcctatttg aggtagtttt
    20641 ttaccaacac cttttccggg caggataggt ccttctctaa tctgtatatt acctatgtta
    20701 ctctgcgacc ccaagcaagc atctatagcc aagaagttac cttgtatatg tgtatttttt
    20761 atagtatcta aagactcata tatatttaag gcgtgaatag ggttatctag tgtaccgtaa
    20821 acggggtatt taaagttact gttcttaagt attgttccaa ctaaagggcc taaagtatca
    20881 cctatagccc tgtctgttcc tatgcaaaca acaatcgtat tttcattaat tatagttttt
    20941 agaactgaac ttagcatctg tataacatca tcatcgctgt agtttacttt agctaaatac
    21001 aataggaaca cccccttcaa aaaaatatat gaataaaaag cattaaaaag acctaacttt
    21061 aaatttcaga tagatagaaa attttatttg tcttacaaaa aaaggaatag aaaaaatatg
    21121 actaaaaata ttgacaaaat tttaaaaaaa tagtaagcta gtaaagtaaa acaaaactta
    21181 aatcttgatt accttatcaa gagaggctga gggataggcc ctgtgaagcc cagcaaccac
    21241 ccaaatggga aaaggtgcta attcctacaa gacaaaagtc ttgaaagatg aggtcagtta
    21301 attagtatgt aattacgatt attaacctct tcttataaag gagaggtttt tttattttga
    21361 gtaaatttct aaaattaaaa ataaggtaaa acctataata aaaattaaga ataaataagg
    21421 gggaataaaa atggcaagac atttatttac gtcagaatca gttacagaag gacatcctga
    21481 taagatatgt gaccaaatat cagattcaat attagatgca ttattagaaa aagacccaca
    21541 atctagagta gcttgtgaaa ctacagttac tactggttta gttttagtag caggagaaat
    21601 aagtacatct gcttatgtag acattcctaa attagtaaga gaaacagtaa gagaaattgg
    21661 atatacaaga gcaaaatatg gatttgattg tgatacttgc gcagttataa cttctattga
    21721 tgaacaatct ggagatatag ctatgggagt tgatgaaggt ctagaaagta agactggaga
    21781 agagatagaa gaagaaatag aaaaagttgg agctggagac caaggtataa tgtttggatt
    21841 tgcatgtaat gagactccag aattaatgcc acttccgata tctttggcac ataaattatc
    21901 aagaagactt acagaagtta gaaaaacagg tttagttgat tatttaagac cagatggaaa
    21961 aactcaagtt actgttgaat atgaaggaag taaagctgta agagtacata cagttcttat
    22021 atcagctcaa cattgtgaaa cagtatcaaa tgataaaata agagaagatt taattaatca
    22081 tgttattaag gaagttatac cagcagaatt acttgatgaa gagactaaaa tttatataaa
    22141 tccaacagga agattcgtta taggaggacc acaaggagat acaggtctta caggaagaaa
    22201 aataataata gatacttatg gtggatattc tagacatggt ggaggagctt tctcaggaaa
    22261 agaccctaca aaagttgata gatctgctgc ttatgcagct agatatgttg caaaaaatat
    22321 tgttgcggct ggtcttgcag acaaatgtga gatagaactt gcatatgcta taggtatagc
    22381 tagaccatta tctatattta tagatacttt tgggacaggc aaggtttcag aagaaaaact
    22441 tgttgaatta gtaaataaac actttgattt aagaccggga gcgataataa gagacttaga
    22501 tttaagaaag cctctttata aaaaggttgc tgcttatggt cactttggta gaactgatat
    22561 agatttacct tgggaaagaa ctgacaaggt tgagcagtta agaaaagatg ctttaggtga
    22621 ataattttta actaaaaagc tgttagaatg taattttatg attactttct aacagctttt
    22681 ttattatgag ttaaatattt ttaataaatg ttaatttatc atcatataat gaataaacag
    22741 tatttaatct ggtcaataca ttttatataa tactctacta aatttataca tattatggga
    22801 tatatgttaa aggatggtta agaatgtgtt aactaatgtt aaataattaa aaatatattg
    22861 aaatatcaca ataatgagtc taatataatc ttaataaact tacactttaa aaataatttt
    22921 aattgggggg gagtagtgta tgtcaggcaa agtaaatatt aaaacggtta taagttttgc
    22981 tggagcttat gttgctactg taataggttc tggatttgca actggtcaag aaatactgca
    23041 attttttacg ttttatggat atgcgggtat tataggtgga ataatctcta tggtactatt
    23101 ttcatggttt ggagcagaag ttatagataa gggaagagaa ttgaaactta aggagccaat
    23161 aaaaatttat caagtatatt gtggaaaata tcttggaaca ttttttgaat ggtttggtcc
    23221 attgttttta tttggaacat tagtaataat gattgcagga gcaggagcta cattatcaga
    23281 gtactatgga ttaaatccat atgtaggtag gattggtatg gcaatcgttt ccctaataac
    23341 tgtttcatta ggtttgacaa ggctttctaa aatactaggt aatataggac ctataataat
    23401 aatatttaca cttttagtag gagcaattag tttatttagc aatattgatg ctttatcaaa
    23461 tgctggaaat atggttgata gtttaaatat taaaactgct acatcaaatg gatatttctc
    23521 gggagtactt tatacttgtt acaatgtaat aatagtaata acattcttga caggaatggg
    23581 agcttctgca gtaaataaga aagatgctgt atggggtggt atagtaggtg gagtagcact
    23641 tatggcagca gctataatga tgaatttggc attactttca gacataggaa atatatacac
    23701 aaaagagata ccagcacttt acttagctga taagatatct ccaataatag gtattttatt
    23761 ctcagtagta cttttactag gaatatacac tacagctgta ccattgttat ggtcagtaac
    23821 aaaccgattt gtagaagatg accaccctaa gtttaaaatt ataacaatag tggtaagtat
    23881 attagcttgt ataggaggtt tactgccatt tgataagtta gtaggtacac tatatccata
    23941 tacaggttac atgggaattt taattttact atgtatgctt tatagaagaa ttactaaaac
    24001 tgaggggtac aaggagaata aatctgaaat aagttagtac tgtaatatac ttatgaaatt
    24061 taatttatac tctaaatata gagtaattaa aataaaatag ctatttaaat atggtacctg
    24121 tatttcatgg taccatattt tatggatgca gatttttttt gtttctgata aaatgtataa
    24181 tagttggaaa ttacgttaag tataaaaata taaaactttt ctacgattat catagtttta
    24241 atatataaaa ttatactaac atttaaatgg agcgattatt agtattttta ggagataaaa
    24301 atggaaaaat tagaaggaat gataagtgaa atagtcttta aaaacgaaga taatggttat
    24361 acaatagctc acctggtaaa tgaaaatgat gaaattgtgg ttgtaggatg tatgcctact
    24421 ttggcaattg gagaaagcat agaagttgaa ggaaagtggg taaatcataa gatttatggg
    24481 actcaatttg aagtgaatag ttttatgcca gtaacaccat catccttaga aggaatttat
    24541 gtttacttat cttctggaat gatacatggt attggtgaaa aaatggcaaa aagaataatt
    24601 gatacgtttg gtgtagatac gttagaggtg atacaaaatt caccagaaaa actacaagaa
    24661 gtagaaggta tagggagtaa aaaagtaaaa caaatagtaa aaagttatga agaagacaga
    24721 gaattgagaa atataataat acagctatct ccttttggaa taacaccaaa ttactgccta
    24781 aaaatatata aaaaatataa aagcagtgca atagaagtta taaataaaaa cccataccaa
    24841 cttgctgaag atataagagg aattggattt aaagtagctg atagtatagc aagtaaaatt
    24901 ggtatagata aaaactctaa agatagaatt tgtcagggaa tcttatacac tttaaataaa
    24961 tctttaagta atgggcatac atatttacca gagcatgttc taatacaaga ttcggaaaaa
    25021 ttgttggagc taaatggaga aatactaaaa gagtgtgtaa tgatgctagt ttataatcaa
    25081 aaaatacata tagagaaagt aaacaatgaa aatcttatat accttatgcc atactattta
    25141 gctgaaaatg gagtatgtag tcaaatagta aaattatcac agtatgaatt tgaagactta
    25201 aaaatagata tagataacga gattaatgtt ttagaagaag ataagaaaat taagttagca
    25261 gaaaaacaaa ttttagcagt caaagaatct gttaatagtg gagtattaat tataactggt
    25321 ggaccaggaa ctggtaaaac aactaccatt aatgctatca tagatatatt tgaaaataat
    25381 ggtaaaagtg tgactttggc agctccaacg ggaagagcag caaagagaat gagtgaaact
    25441 tctaataaag aagcaaaaac tatacatagg ttgctagaaa tgggattttc aacagatgat
    25501 gatttaactt tttttaagga tgaagaagac ccaataaatt cagatgtaat aattgttgat
    25561 gaggtatcaa tggtagacat tatcttaatg tacaatttac ttagagctat aaagttagga
    25621 acaagagtaa ttttagttgg agatagtgac caattacctt ctgtaggtgc tggaaatgta
    25681 cttaaggata tgattaattc taatattata aatgtagtta aattaaatga aatatttaga
    25741 caagcgcaag aaagtatgat aattgtaaat gcccataaga taaacaatgg agaaccactt
    25801 tatctaaata caaaaggtaa agatttcttt tttataagaa aatcaactaa tgaagaaatt
    25861 ttaaatgaaa taataggatt ggttaatgaa agattaccta aattttataa agttgagaaa
    25921 ttaaaagata tacaagtttt atcttcaatg agaaaaggtg aattgggagt tactaatctc
    25981 aatatagagt tacagaagta tcttaacaaa aaagaaaaat ttaaagttga agaaagtttt
    26041 tctaaaagat tatttagagt tggcgataag gtaatgcaag taaaaaataa ttatacaaaa
    26101 aaatgggaaa cagaagacca aaaagaaagt ggagaaggta tctataatgg agatatagga
    26161 tatgtttatc acatagataa agataagaaa actatttata tattatttga ccagactaaa
    26221 attgtatcat acctctatga tgaattagat gaaattgacc atagtttttg tacaacaata
    26281 cataaaagcc agggaagtga atttccagtt gtagtattgc caatagcgtg ggctcctcct
    26341 atgttactta gccgtaattt attatataca gcagtaacaa gagcaaaaaa attagttgta
    26401 ttagttggag atgtgaaata tcttgaatat atgataaaaa ataatagagt taatcaaagg
    26461 tattcaaatt taggatataa gctaaataaa tttaaacaag aagggttgtt gatagaataa
    26521 atatgaaaat atgcaatgat aattttatta agaattttaa aaatatgatt aataaatgtt
    26581 tggattttat atatcctgag aatataagtt gcataatttg tgataaatcc ataaagaaaa
    26641 caaatactta ttcaatatgt aaaagttgtt ttaaagaaat gaattttata caagatggtt
    26701 gcatgaagtg tggaaaacca ataatacgtc attcaattga aaaagaattt attgaagagt
    26761 gtagttattg ttttaataaa gacttttatt ttgataaatc aatatcttgt attgaataca
    26821 atgatgtgac aaaaaagatg gtgttagggc tgaagtataa ccaaaaaacc tttatggcta
    26881 agtatatagc tcaaataatg aaagaaaaat tatatttaga aaacataaaa tttgattata
    26941 tattatttgt tccacttcat aaaaaaaggc taaataaaag aggttttaat caggcacaaa
    27001 aaatagcatt taatttaagt aaaatagtaa atattccatt attagattgc ataagtagaa
    27061 aaaaatatac aagaatgcta tataaattga ataagaaaga acgaaaagaa gaattaaaaa
    27121 atgtatttgt tgttaaagaa aatgttaaat taataaataa taaaaatata cttttaatag
    27181 atgatatatt tactactggt ctaacaacaa acgaaatttc taaactttta aagttatcag
    27241 gtgctaataa ggtttttgta ttgactctac ttacaaaagc aaatgataat tatattatgg
    27301 aataatctta tatattgaca attttagttt aaaatattaa aatgaataag tgatatttag
    27361 gtctgtggtt gaaagtccaa gccagtcgca ggcaaaggga tccacgtaag ttaacactaa
    27421 aaattgggtt aatgatcatg gtgcggctta gaagtaagac ctaccgataa taaaatcgag
    27481 agagagtagt agtgcggcga acccaagcga accctccagt aggcgagtgt ggggtcaaaa
    27541 accaggtcag ctaaatatca tattaaaaga gagctagcat acctttatgt atagctcttt
    27601 tttatatata ataaatttag gttgagtcat aaagaggtga tatgtttgaa taaaagacaa
    27661 gaaaatttat taacaacatt gctattaaaa gaagagttta taaatgttaa taagattgcc
    27721 aatgattttg agtgttcaga aaggacaata agaaatgatt gcaaatatat tgatgaatgg
    27781 ttatctactt tttgtaatgc ttatatcaaa agaaaaccta atattgggat taaatttagt
    27841 ggagatggaa cagacaaaat actggtaaat cagaagttgc gaggtgaagt taaaagagta
    27901 aatagtgagc ttcataagca agttgagata ttaaatttac tactttgtaa taataaaaaa
    27961 gttactttaa atgatttatc taataagttg tacataaata aaaatattgt cagagaagaa
    28021 ataagtaaat tatcagtagc attaaataat tataatttaa atatctcgac taaaaaaggc
    28081 agtggtatat atattgaagg ggatgagaaa gacataagaa taatgttagt atcattctta
    28141 tttaaatata tagataaata cagattaaac atagatgaaa tagagtactt ccatatagta
    28201 gatataataa ttgtaaaaaa cataatgctt actatagagg aggatatgga tataagactt
    28261 acagatatat cattcaagca attgatgcta tttttgctta taaatataat acgaataagg
    28321 ctgggaaatt ctttaaaagt atcaaatact aagaaagagc ttaagctaaa aatgcttata
    28381 ttggatatag aagatgaatt gaaatctaat ttatccatag tattaaatta tgaagaaaaa
    28441 ttgtttatag aatctttaat attgggtatg aacaaacaaa taaatagtaa taatattaag
    28501 aaatctttat atctaaatga agaattagca agttatacaa aaaaaattat aaatttagta
    28561 tcagaagaat caggaataaa ttttaataat gatatattac tttatgaaca attaatatgt
    28621 catttgaatg ttacaatgca tcaaatgaaa agcaatgttt acttagaaaa tccactttta
    28681 gataacataa aaactaaatt ttgtttttta tttacagtaa tatcaagttc aatagaaatt
    28741 gaattaaaag gaaaacaaat aacggaagat gaaattggtt atcttacact tcactttcaa
    28801 acctctctag aaagaaaata cagcaaaagg gaatcaaata aaaaggcaag tattgtatgt
    28861 ccatttagtt ttggagtaag tatgctatta aaagtaaaga tagaaaagag atttgataac
    28921 ataaaaatta ttgaaacatt aagagaggaa gatttaaaaa gagataactt taataagact
    28981 atagatttta taattgcatt tcaagagtat gaaaatatcc aaaaaccaat ttttataaca
    29041 acaccattat ttactgatga ggatgagaat aaacttaaag agttcacaaa caaaataaaa
    29101 gaaaaagaca cttcatataa acttatgaac agattaatga tgtctgatta tttaataaga
    29161 gagttagaac atgatgatat ttatgaagct ataacatatt taactaattt attaattgaa
    29221 aaacattatg cagaaaaaga gtatttacaa tctattataa caagagaaaa gtcatatcca
    29281 accaatgttg gaaaaggaat attattccct catggagaca tgaaatatat aaaacaatct
    29341 gttttatgtt ttgcaaggtt aaaaacacca ataaaaatta gaaatggaaa ggatataaag
    29401 attatacttt tgttagcata taaaaaagat gatgatagaa aagtatttag agaattattt
    29461 aaagaaatat ctaatttaac agaggatgaa aatatgctag atattctaag taaatgtgac
    29521 attgaaaagg taaaagatat tcttatataa aattcatagt gaactatgga taagcacaaa
    29581 attttccatg tgatggaaaa agttgtgcat gtttttttgt ttttataaga tattatatgt
    29641 ttgtaaggta taaataatct aaaagtagag aagcaactta ggaggaaaaa atggaagaaa
    29701 tagttttaaa gattataatt catgctggaa atgcaaaatc tatgctttat gaggcacttg
    29761 actatgcaaa ggaaaacgat tttaaaaaag cagatgaatt aattgaaaat gcaaatgaag
    29821 aaattttaaa agcacataaa gtacaaactg aacttataca aaaggaagct gggggagata
    29881 aatcagatat atctatttta ttgattcact ctcaagacca tttaatgact tgtatgagtg
    29941 agagaaacct tataaaagaa atgattatgt taagaaaaga aattcaaaaa ctaaaataaa
    30001 aaattaaggg ggatttaaaa aatgaaaaga aaagtatatt tattttgtag ctttggtatg
    30061 tcaacaagtt tacttgcaga taaaatgcag aaggtagcag atgaacacaa tttaccaata
    30121 gaagtagagg catttccgat agcagaaatt gacaaaatag ttgaagaaaa aaatccagat
    30181 tgtatattat taggaccaca agttaaatac atgctaaagg agttaaaacc aaagtttgaa
    30241 gctcaaggaa aacttataga tataatcaat gaagttgatt atggaactat gaatggggaa
    30301 aaagtattaa aacttgctat aaagctaata aaatctaaac aagcgtagaa ttatagtaaa
    30361 aaataatagg aaatgagggt ggatagatga atagattgga aagaatactt atgccattgg
    30421 ctgaaaaaat aggtaaaaat aaattattaa ttgcaattag agatggtttt ttagtatcat
    30481 caccattatt aataataggt tcattatttt tattagtagc aaattttcct ataaaaggat
    30541 ggaatgaatt tgtaggtcaa atttttggtc cagattgggc tgtaaaattg caacaaccaa
    30601 ctgtagcaac atttgaagta atgactctac ttgcagtttt agggattgga tattcttatg
    30661 caaagcaaat agatgtagac ccaatagcat cagcagcagt tgcaatagtt gcctttttta
    30721 taataacacc atttgtaata ccatatacac cagaaggaac agaatcagtt tacatggtaa
    30781 caggtatacc actaggttgg atgggttcta agggaatgtt tgtaggtatg ataacagcaa
    30841 taacctctgt aaaattattt gctgcagttg taaaaaaagg atggacattg aaaatgccag
    30901 atggagttcc tccaactgta tcaaaatcat ttgcagcatt aataccaagt gcaatagtta
    30961 tggtagtttt ctttttagtt aagatagctt ttgaagctac accatatgga agtatacatg
    31021 aatttatatt taagttttta caaatgccat tattaaaatt aggaaatagt ttaggtgcta
    31081 tggcaatcgc ttatatattc ttacatttat tctggttctt tggaataaat ggaagtagtg
    31141 ttgttggggc tgtgtataat ccaatattaa aaattctatc agctgaaaac ttagctgctt
    31201 ttcaagctgg ttcaaaaata ccaaacataa taacaggtca attccaagat atgtttgcga
    31261 catttggtgg agcaggtagt acactatcat tagtcatagc tatgttatta atatgtaaaa
    31321 gtaaacgtat aaagtcaatg ggaaaactat caattttacc aggaatattt ggtataaatg
    31381 agccattgat atttggtcta ccaataatgc ttaacccaat actattgata ccatttgcaa
    31441 tagttccaac aataaatata ataatagctt acttctgtat gtcagcagga ttagtgcctc
    31501 ttacaaatgg agttcagtta ccgtggacaa ctccaattat attctctggt tttttaacaa
    31561 caggatggca aggtgcagtc ttacaattag tacttcttat actaggaata tttatgtata
    31621 taccatttat aaaaatgcta gataagcaat acttgagaga agaaaatgaa actgttgaag
    31681 aggaagatga tgatatatct tttgatgatt tagtattata ggaggaagat tatgaagaaa
    31741 atagttatga tattggacca aatacaagct ggagctggag gaaaagagaa aagtaatata
    31801 cctcctgctg gaaaatcaag cccattagga ccaggtgtaa tgatggagca atttttaaat
    31861 gaatctaagg taatagctac cttattttgt ggggatgaat tttttgtaaa taatcaagaa
    31921 gaagtaacga gtaagatgat agctatggta aaaaaattaa accctgatgt agtaatctgt
    31981 ggaccaagct ttaattacga aaacttttct aagatgtcag caatactgtc taaaaatata
    32041 aatgataaaa cagatatacc agcttttgca gctatgtcag aagaaaatat agatgtgata
    32101 aacgaatata aaaatgacat atgtatagtt aagactccaa aaaaaggtgg aattggtctt
    32161 aatgattcgt taaataacat atgtaaattg gcaaaagcaa tagcaaataa agaagatata
    32221 actttgatga aagaagaatt ttgttattaa taagagtatt aattattagc aagtttaaat
    32281 attatactat ttataataag catacattag taaaatctat ataatttaag gaggggaatt
    32341 ttaacatgtg gggaatgata gcgacatgga gaatggccct agaaggaata actgaggcat
    32401 cagaacattt agaaaaaggc atggaagcag gtgatgctgt agagcttgct gtaagaagag
    32461 ttgaagacta tccattctat aaatcggttg gatatggtgg acttccaaat gaaaattgtg
    32521 aggtagaact tgacgctgca tttatggatg gtaacacatt agatattggc gcagttgctg
    32581 gtataagaga ttattctaat cctgtcagca tagctaggaa gttaagttat gagaaggtaa
    32641 ataatttttt agttggaata ggtgctgaag attatgctca taaaaatgga tttgaaagaa
    32701 aaaatatgtt gactgataga gcgaagttac attataaaaa gagaaaaaaa gagactttag
    32761 acaaaggatt aagcccatat gctggtcatg atactgttgg tatgatatct ttagacaaaa
    32821 ctggaaaaat gtgtgcagct acatcaacaa gtggattgtt tatgaagaaa agaggtagaa
    32881 taggagattc tgcactatct ggttcaggat tctatgttga tagtagtata ggaggagcta
    32941 cagctactgg tttgggagaa gatttaatga agggatgtat atcttatgag atagttagac
    33001 ttatgaaaga agggaagcat ccacaagaag catgtgatat tgcagtaaat gaacttgata
    33061 aacagcttat caaaagaaga ggaaaagctg gtgatttatc attagttgcc atgaataata
    33121 aaggtgaatg gggagtagct acaaatatag ctgattttac tttttcagta gtaactaaag
    33181 aagaatctcc tactgtatat atttcaaata gagtagatgg aaagactata cataaggtta
    33241 tatcaaatga gtggatggaa gcatatgagg ctagaataaa agcaccaata gaagtaagtg
    33301 agtaaagtag tggttacata attaaaatag agttttataa taaggagatt tttatgaata
    33361 tcataagtaa taaaatagat gagttaaaag aagatttatt aagtgatatt atagatattg
    33421 taaaaatacc tagtgtcaaa ggggagtcag aaaatggctt cccttttggc gaaaaagtag
    33481 gggaggcact taataaagca ttagaaatat cagaaaaatt gggatttaag gttagaaact
    33541 tggataatta tattggttat gcagagcatg gagatagtga tgattatgtt tgtgtaattg
    33601 gacatgtaga tgttgtacat gaaggagatg gttggaagca tcagccttat aagggagaag
    33661 aaactaatgg aagaatttat ggacgaggag tactagacaa taaaggacct ataatgtctg
    33721 ccttatatgg attatatgct attaaagaat taaacttaaa attagataag agagttagaa
    33781 taatatttgg tacaaatgaa gaaagtggat ttgaagatat accatattat ttagaaaaag
    33841 aaaaagcacc tattatggga tttacaccag attgtaagta tcctgttgta tatggtgaaa
    33901 aaggcatggc aaagattaga ataaaaagta aaatcaatta tgaagaagat gtatacctag
    33961 gttttataga aaatatgtct gaaaatgtgc ttgttacata taaagagctg aatatagaaa
    34021 atagtgatac tatattagat ataaaggtaa aatacgattt tagttataaa ttgaaagatg
    34081 tattagatga aataaaagct agttttccaa atagtatcga tatagaggta atttctaatt
    34141 ttaatcctgt atattttgat aaagagagta atcttgttaa aaagcttcag ctagcttatg
    34201 aaagggttac atcattagat ggaactccag taacaactaa tggaggtacg tatgcaaaag
    34261 taatgccaaa tatagttccg tttggacctt catttccagg acaaaaagga atagctcata
    34321 atcctgatga atacatggat atagaagata taatattaaa tgcaaagata tttgcaaatg
    34381 caatatatga attagcaaag gagtagttat gttagaaata ataggaatgt cagtagaaga
    34441 cgctaaaatt atagaagatt gtggtgcaga tagaatagag ttagttagtg ctttaactga
    34501 aggtggattg acaccaagtt ttggtcttat agaaagtgtt gttaacagtg taaagatacc
    34561 tgtgaacgtg atgataagac atcatgcgaa aagttttgta tacagtaaag aagatataag
    34621 tataatgcaa aaagatataa gtgtggttaa agagattggt gctaatggag ttgtatttgg
    34681 tgtattggat aaaaacaata gtatagatga gaaaaatcta aatgttttat tgaaatgttg
    34741 tgataatctt gatgttacat ttcatagagc aatagatgaa tcaaatacaa tagatagtgt
    34801 taaaattttg aaggattatg ataaaattac gaatatatta acatcaggag ggaaaggaag
    34861 tatagttgat aacatacaaa tgataaagaa tatgatgctt agttctaatc acataaaaat
    34921 tcttttaggt ggaggtctta attttaataa tatagaaaag ataaaggaat tgactaaggc
    34981 aagtaatttt cattttggta cagcgattag aataaataac agtccttttg aagatataga
    35041 tagacaaaag cttaaacaac tcgtaaatat aatttcaaga tagtatatga atataaaata
    35101 cttagtttaa ataaagagag taagttaatt ataatttggg tatatgaatg ttaataggta
    35161 ttaaatatga aattattgtt gagtatgctt tataactttt aagtagtttt aaatataaat
    35221 aatgaaagaa aagatagatt atggaggttt tagagggttt atatttatta aaaaattata
    35281 aaggtatatt ggcatataat acacataatt tcctaaaatt accatcttat gacatgaatt
    35341 cacatattaa taaacaatta atggagattt ttgtggatag aaataggagt aaaaatagct
    35401 ttaaataaac aaaaacaaga gttattaaca gttttatcca cattatccac aggtgtttgt
    35461 aataatatta atccacataa gtatcaatgt aactaaaaat gataaataat tctatcaatt
    35521 gaatagaaaa aatcataaaa gtaaataata aaaagaggat tatgagagtt cgtgtagaat
    35581 atattattaa agtataaatt ttcttatact ggcataattg aagggagatg tatttatgaa
    35641 cataattata tctggaaaac aaatcgaatt aactgatgca ataaaaaata aaatcgaaac
    35701 taaactaagt aagttagata attacattca tccagacact gatgtaaaag ttacagtaag
    35761 tgcgagaaaa gcaagacaaa aaatagaagt aacaatagct actgtaaatg gtcctataat
    35821 tagagcagaa gatatgcagg aaaatttata cacagctata gatgttgtat atgataaatt
    35881 aagtaaacaa ttaaaaaaat ataaaaagag attacaagat aaacataaag acaacaagag
    35941 tataagattc caagatgcag agataaatct agctgatgaa caagaggatt atggggatga
    36001 aaatcaagaa ttagtaattc aaagacgtaa gaaatttagt gttaagccaa tgagtgaaga
    36061 agaagctgta ttacagatgg aattaatagg acatgatttt tatatgttca agaacataga
    36121 ttcagatgaa atagcagtag tttataagcg taataatggt ggatatggta taatagaaca
    36181 tgaataaagc aatttagatt taatcatatt agctatcgat aaataaatta tcgatagctt
    36241 tttaaattaa tattaaaagt atagttttta tggtaaaatg aataatagta caataaagaa
    36301 cgaggagaga tgtaaaatat gagctttatg gataatttat tcaacatggc agataaaaaa
    36361 gaattaaaaa agttcaataa aactgttgat ataatagatt cattagaacc taaatttgaa
    36421 tctatggcag actcggaact taaaaatatg acaaatatat ttaaagaaag attagcaaat
    36481 ggtgaaagta tagatgatat acttccagaa gcttttgcag tagttagaga agtttctaag
    36541 agagtgttag gacttagaca ctacagagtt caaatgattg gaggtatagt actacatcaa
    36601 ggaagaatag cagaaatgaa aacaggtgaa ggtaaaactt tggttgcaac tgctcctgtt
    36661 tatttgaatg cgcttactgg aaaaggtgta catgttgtaa cagtaaatga ttaccttgca
    36721 aaacgtgata gagaccaaat ggcaaaaatc tatgagtttt taggaatgag tgtaggcgtt
    36781 attatacacg gtcaaaatcc aaaagttaga aaagaacaat atgattgtga tataacttat
    36841 ggtacaaata atgaatatgg atttgactat ctaaaggaca atatggtaat acacaaagag
    36901 caaagagttc aaagaggatt aaattatgct atagtggatg aggttgactc tatactaata
    36961 gatgaggcta gaacaccact tatcatatct ggacctggag acaaatcaac tcacttatat
    37021 tcagatgcaa acacatttgt tttaacctta aaaccagatg attatgaatt agaagaaaaa
    37081 gataaggctg tatctctaac agcatcgggt atacaaaaag cagaagtgta ttttaatgtt
    37141 gataatataa cagatatatc tcatacagaa ttataccatc atataaatca agctttaaga
    37201 gcacatgtaa taatgaagaa agatgttgat tatgttgcta aagatggaga aatagtaata
    37261 gtagatgagt tcacaggtag acttatgttt ggtagaagat attcagaagg tttacatcaa
    37321 gcaatagagg ctaaagaagg tcttaaaata caaagagaat ctaaaacact agctactgta
    37381 acattccaaa attactttag aatgtacaaa aaactttctg ggatgactgg tacagcaaaa
    37441 acagaagaag aagagtttaa agcaatctac aaaatggatg ttttccaagt acctactaat
    37501 aagcttatga taagggaaga cttaccagac tgtgtataca aaagtgaaat aggtaaattt
    37561 aatgctgtag cacaagaaat aattgaaagg cacaaagtca atcaaccaat acttgtaggt
    37621 acagtatcaa tagaaaaatc agaattatta tcacaaatac taaagaaaaa gggcataaag
    37681 cacgaggtat taaatgctaa gcatcatgat aaagaggcag aaataatagc acaagctggt
    37741 agacttggag ctgttacaat agctactaat atggctggtc gtggtacaga tatagttcta
    37801 ggtggaaatc cagacttttt aactaagaga gaaatgagaa gaaatggatt taaagaagaa
    37861 atagtaaata gagtagatac tccaatagaa ggtatacctg taaaaggtaa tgaaattcta
    37921 tttgaagcta gagaagagta tgaaaaacta tttgaaaagt ttaagcaaca aacacaagaa
    37981 gaacaaaaac aagttgtaga agcaggtgga cttgctataa taggtacaga aagacacgaa
    38041 tctcgaagaa tagataacca gttgagaggt cgtgctggac gtcaaggtga cccagggagt
    38101 tcaagattct atataggtct tgatgatgac cttatgagat tgtttggtag tgatagaata
    38161 tctggtattg tagataaaat aggtcttgaa gaagacatgc cgatagaaca tagaatatta
    38221 tctaagtcta ttgaaggagc acaaaagaaa gtcgaaggta aaaactttgg aataagaaag
    38281 catgtacttc aatatgatga tgttatgaat aaacaaagag aaataatata tgcagagaga
    38341 aaacgtgtat tagaaggtga agatttacaa gaacaaatac aatcaatgac tcattctata
    38401 atagaagaag cagttactct ttatacacaa gataaaggat ttgatgaaga aggattcaaa
    38461 gaacatatgt ataatctgtt cttgccaaaa ggtagcatag aaataccaga aatagaaaaa
    38521 cttaatccag ttgaaataac agaaaaagtt tatgaaatag ctatgaagat atatacttca
    38581 aaagaagaac aagttggcta tgagagaatg agagaagttg agagagtaat cttacttcaa
    38641 gctgttgata accattggat agaccatata gatgctatgg accaattacg ccaaggtatt
    38701 ggtcttcgtg ctgtaggtca gcaagaccca gttattgctt ataaaatgga aggttttgat
    38761 atgtttgatg aaatgaataa acatatcaaa gaagatactg taagatattt atttaatata
    38821 acaatagaaa ctccagtgga aagaaaagca gttgtagatg ttgaaaatct atcttctcca
    38881 tcagatggaa cacttccaac aagtaaaact gttaaaaaag atgaaaaggt tggaagaaat
    38941 gacttatgcc cttgtggaag tggtaaaaaa tataaaaact gttgtggaag ataatctcgg
    39001 aggattaaat gttaaagtta caagagtata gacatagtat ggagcagatg gcttcaaatt
    39061 tagaagaatt gagggtttct ctttgacata gcttcattga tgaaaaatat acaaattaat
    39121 gaagaaaaga tgaatcaaca agatttttgg aatgataatg aagtcgctca aagagtactt
    39181 caagaaaata aatctttaaa agagacatta gaagaatatg aaagcttaaa aagcttatta
    39241 gaagatatag aagtattaat tgaaataggt ttagaagaag atgatgattc tgtagaaaga
    39301 gatatagaaa agtccataga atcaatggaa gaaaaattat ctgaaatgaa aataaagact
    39361 cttctaaatg gagagtatga taaaaataat gctatattat ctataaatgc tggtactggt
    39421 ggcttagatg ctcaagattg ggctcaaatg cttttgagaa tgtatataag atggtcagaa
    39481 agtaagggtt ataaagttaa gcttttagat ataatatcag accctgaagc agggataaag
    39541 acagctacaa ttcttgtaga aggaacaaat gcttatgggt atttaaagag tgaaaaagga
    39601 gttcatagat tagtgagaat atctccattt gacccatcag gaaaaagaca tacttcattt
    39661 gcatctatag atgtaacacc agagttagat gaaaatatag aagtagaaat taatccatca
    39721 gatttaaaga tagacacata tagagcttct ggagctggag ggcaacatgt aaatacgact
    39781 gattcagcag ttagaataac acatatccct actggtgtag tagttcagtg ccaaaatgaa
    39841 aggtctcagc atctaaataa ggacagagct atgagacttt taatggcgaa attgatagaa
    39901 ttaaaagagt tagagcaaaa ggaaaaaata gaagatatac aaggcaaata ctcacaaata
    39961 acttggggta gtcaaattag gtcatatgtt tttcaaccat ataaattggt taaagaccat
    40021 agaacaaatg ctgagtttgg caatgtagat agtgtaatga atggaaatat agacttgttt
    40081 attaatgaat acttaaaaat gaataaaata gtttaataaa tatgcactgt aattaagata
    40141 tatgtataag aaggttagtg cttaatatgc acttacagca cttaggctga ggacgataac
    40201 cctcagcctt cgttctgttt tgttatactt atgaaaaact aacattagga gtgaataaat
    40261 tggatataaa tcaaatctta aaaaaagagt ttaatcttag agatgaacaa ataaataata
    40321 cattaaaact tattgatgaa ggaaatacaa taccatttat agctagatat agaaaagaaa
    40381 tgactggcga aatgagtgat gttacactaa gagaatttta tgaaaaatta atgtatttga
    40441 gaaatcttca aagtagaaaa gatgatgtag ttagactaat agatgaacaa gggaaattaa
    40501 cagatgaaat aacacaaaat atagaaaaag caaaaacatt acaagaagta gaagatatat
    40561 atgctccata caaacaaaag aaaagaacga gagcaacaat agcaaaagaa aaaggattag
    40621 aaaatttagc attgtcaata ctagagaata atttagataa tatagaaata gaggcaaaga
    40681 attatcttga tgaagagaaa gaagttcttt ctattgaaga tgctctaaaa ggtgctagag
    40741 atataattgc agaactagtc tcagatgatg ctaagattag aaagtatata agagaattag
    40801 ctttaagaga aggtatgata gttagcaaaa gtgctactga tgagaaatcg gtttatgata
    40861 tgtattatga ttatagcgaa gcagtaaaaa gtatggctcc acatagagtt ttggcaataa
    40921 acagaggaga aaaagaaagc ttcctaaagg ttaagttgga aataaataat gataaagttt
    40981 taaattacat aataaacgaa tatgtaaatg ataaaaattt caaaaataaa gaagaaatcg
    41041 taagttcaat agaagattct tataaaagat taattttccc atcaatagaa agagaaataa
    41101 gaaatcattt aacagaaata gctcaagaaa gagctataag tgtatttgga aagaatgtta
    41161 aaagtttatt gcttcaacca ccagttaaag acaaagtagt tatgggattt gaccctgcat
    41221 ttagaactgg atgtaaaata gctgtagtag ataaaaatgg taaactacta gattatacaa
    41281 cagtatatcc aacagaccct caaaatgatg tagagggagc aaagaaagtt ttaaaaggat
    41341 tgattgaaaa atacgatata gatataattt caattggaaa tggtactgca tctagagaat
    41401 cagaaacttt tgtatcagaa atgataaaag aaatagatag cgaagtgcag tatgtgatag
    41461 ttagtgaagc aggagcatct gtttattcag catctgaact tgcaaatgag gaacatccag
    41521 atataaatgt atcaataaga ggagctatat ctatagctag aagattacaa gacccattag
    41581 cagagcttgt aaaaatagac cctaaaagta ttggtgttgg tcaatatcag catgatttaa
    41641 acaaaaagag attagaagaa gtactagatg gagttgttga agattctgta aatagtgttg
    41701 gagtagattt aaatactgca tcatactccc tactagaaca tgttgcagga ataagtaaag
    41761 ctatagcaaa aaatataata gcatatagag aagaaaatgg agattttacg tcaagagcac
    41821 aattgaaaaa agtaaaaaga ctaggacctc aagcatttac tcaatgtgct ggatttatga
    41881 gaatcttaga gggtaaaaat ccactagata atacaggtgt gcatcctgaa agttatgata
    41941 tatgtaaaaa aatgattgag ataattggat attctttaga tgatgtaaag aataagaata
    42001 taggtgaaat agatgaaaaa ataaaagaaa ttggcttgag ggaattaagt gaaaaactgg
    42061 aagtaggaca agttacatta aaagatatca tagctgaaat caaaaaacca ggaagagacc
    42121 caagagaaga aggtataaaa cctatactta gaactgatgt cttaaaaatt gaagatatac
    42181 aagagggtat gactttaaaa ggtacaataa gaaatgttgt agactttggt gcatttgtag
    42241 atattggaat aaaaaatgac ggattagttc ataaatcaga aatgagtaat agttttgtga
    42301 aagaccctat gagtattgtt acagtaggtg atatagtaga tgtaaaagtc attggaattg
    42361 acttaaacaa aaaaagagtt gccttatcaa tgaaaaaata gataagttta tgtatggtta
    42421 taatacttag attctatatt tgtaaataag attactcgag tgtataaatg ttaaaaattt
    42481 gtaaaagtat atagtaagaa aatatattaa aataagaacg atagtcttga aaatcaggag
    42541 gaaaatgaat gatttttata aaaaatggta aaataaatac cataacaaat gggataattc
    42601 atggagatat acttatagat gaaggaaaaa taatagaaat tggagaagat ttgatagctc
    42661 ctttagatgt agaggtaata gatgctagta ataaacttgt gtttcctgga tttatagatg
    42721 ctcatactca cttaggttta tgggaagatg gtatagggtt tgaaggagca gatggaaatg
    42781 aagagactga cccaataaca ccacaattaa atcctataga tggaattaat ccaatggata
    42841 gaacttttaa agaagctttt gaaggtggaa taacttctgt ttgtacaacc cctggaagtg
    42901 caaatgttat gggtggtcaa tgtatagcta taaagacatg tggaaaaaga attgataaaa
    42961 tggtaataaa aaatccagtt gcatctaaaa ttgcttttgg agaaaatcca aagagctgtt
    43021 atggtcagga tgataaatct cctcaaacta gaatggctat agctgcttta cttagagaaa
    43081 acctaaaaaa agcagaagaa tatttagagg atattgatat gtatgagagt catgatgatg
    43141 aagactgtga aaaacctgaa tatgatataa aaatggaaag tttaatacca gttttaagaa
    43201 gagaaattcc ttttaaggca catgctcata gagcagatga tatgtttaca gcaataagaa
    43261 ttgcaaaaga atttaattta aagcttacat tagaccattg tacagaaggt catcttattg
    43321 tagatgaatt agtggaagaa gggtttcctg taatagtagg gccatctttg tcagaaaggt
    43381 ctaaatttga gcttagaaat ttgacattta atacagcagg aatactttca aatgcaggtc
    43441 ttgatgtatg tataatgaca gaccatccag taataccagt tcaatatctt ccaatatgtg
    43501 caggtattgc agtaaaacat ggtatgaaag aagaaaaagc aatagaatca attacgataa
    43561 atccagctaa gactttagga atagaagata gagtaggctc tatagaagtt ggtaaagatg
    43621 cagacctagt aatttgggat aattctccac tagagattca aagtaatgta ctttacacta
    43681 taataaatgg caaagtagtg tatgagaaaa aataacttga caattattaa aaaattaact
    43741 aatataagag tgtaaggaaa attaaaaaat caaagaagat cttcggggca gggtgaaatt
    43801 ccctaccggc ggtatagccc gcgaactact taagtggttg atttggtgag attccaaagc
    43861 cgacagtaaa gtctggatga gagaagatat ttatggaaga taaataagtt tattttagtt
    43921 tgtttaaact atatccataa aaactcgaag atagggtctt cgagtttttt gtttttccta
    43981 aaaaatataa acatattgat tagggggaaa ataattatgc aaaacacagc aaaaagaggc
    44041 aatatgattt caacaagaac tttagtagta atgtcaattt tatctgcaat atcttattta
    44101 ttaatgttta ttcaagcacc aataccaggt atatttccag atttcttaaa aattgactta
    44161 tcagatattc cagcaatatt cggaggaatg tctctaggac cattagttgg atttggaata
    44221 gttgtagtaa aaaatgtgtt acaagcaata acagcaacaa caactggagg aataggagaa
    44281 tttgcgaata tattaattgg tggttcttat gtaatgatac tttgttattc atataagaga
    44341 agtggagatt taaaaggtgt actgattggt tttgtattag gaacaatatc tatgactata
    44401 attggttcat tagtaaatta ttttgtaatg ttgccacttt atggtcaact tatgggacta
    44461 gatgctataa taggtttagg ttcagctata aatcctcaag ttcatgattt attcactttt
    44521 gtaatttgga tgatagctcc atttaatgtg ctgaaggctg ttataatatc tttagtaaca
    44581 ttgccacttt ataaaaaaat gggaaatata ataaagaaat aattagacaa gaaaatataa
    44641 aattaaatgt attgaatagc cataatttat ttataacttc agtcctatat tgtgattgat
    44701 atattaaata tattatggct ttattaattt atcaaaaaat gtatataaaa taagaaatat
    44761 ttagacaaat ttaaatttta aaataaagga agaattaaaa cgattaacta ttaaaatatg
    44821 aaaaaggtat ctacaatata cagagcgaat ttataataaa caaaaaataa agttattatt
    44881 aaaaaactat aaagattaat aatcaaactt ttaataataa ctaatttaat aatgataggg
    44941 gtgtatattc atgcatttat ctaaaaaaat aaaaaaatta tttttagatg ataaagggta
    45001 ttattttaat agtaattgga aagatattca tattggtatt tatgatacaa aattaggaga
    45061 ttctttaaag tatatcacta atgaatatat tgaaaatatg gaaagggtaa aatacgatta
    45121 tcgtgaatta aaaaatatag aaaatcaaac tgatggtatg tgtattttag caataaggca
    45181 gaattacaag gcattagagt atgtaaaaaa tcaaaccgaa gaattatgtt tagaagcaat
    45241 aaagtataat tataaagcac ttgaatatgt aaaagaacaa acagaatact tgtgtcttga
    45301 agctataaaa aaagattgta atgcacttaa gtatgtacga aataaaacag aagggcttat
    45361 tataaaagca ataagtcatt cttccaatat agatgttgta agtatactaa aggctttaga
    45421 gactcaaaca agaaggatat gtttagaagc aattaaaaaa gatggcaggt gtcttgcata
    45481 cgttagagaa cagagtgaag aattatgtat agaggccatt aagcaaaatt ataaagcatt
    45541 aaaatatgta aaaaatcaaa cggaaaaaat gtgtatagaa tccgtaagac aaaatggtat
    45601 ggcattacaa tatgtaaata aacaaactga taaaatatgt atagaagctg tcaaacaaga
    45661 tggaagaagt atacaatttg tcaacaataa gacagaagaa atatgtataa atgctataag
    45721 atatttaaat aaaaaatata atattaaaga tgtactaagt tacatagata agtatacaga
    45781 agatatatgt atagagattg taagacaaaa tggaaaaatg cttatgtata taaaaaatca
    45841 aacagaaaaa atgtgtattg aagcagtaaa agagaactat aagtctctta agtatgtaaa
    45901 agagcaatct gagagaatat gtaaagaagc attgaagcaa aaccataaag caaaagagta
    45961 tgtaaaaatt gctattgatg attgtatata aggtgtagat acagccatca atagtgaaag
    46021 ataaaaaaag ataaagacaa gtactttata ataatctagg cttatactat aattaattaa
    46081 gcagtgatat aaattcacat gacgattata tcaaaatgga gatgaattga tggcaaaaat
    46141 atatttagaa aatgaaaata aaactagaga aataggatat aaattaggta aacttttaaa
    46201 agaaggcagt gttatctgtt tagtaggaga tttaggagct ggtaaaacta caatgacaca
    46261 aagtttggca gattcattag ggatagaaga ttatataaca agtcctactt ttactataat
    46321 aaatgaatat gaaggaaaaa tacctttgta tcattttgat gtttatagaa taggtagtag
    46381 tgacgaaatg tatgatattg gttatgatga atatgtaaat tcaaatggaa tctgtataat
    46441 agaatgggct aatctaatag aagatatact tccaaaagaa tatttgaata tagaattgag
    46501 atataaagat gaaggaagag aaatgatatt aactccaaaa ggagagtttt ataaagagat
    46561 agttgaggag ttgattaaat aatgaaaata ctaggtatgg atacgtcttc tatggcagca
    46621 agtgtagcag ttgttgaaga tgataactta atatgtgagt ttacagtaaa caacaaaaaa
    46681 actcattcac aaaagcttat gccaatgata gaaaatatgt tgagtatgag tgatttaagt
    46741 ataaaagata tggatttatt agctgtatgt ataggtccag gttcgtttac aggacttaga
    46801 ataggtatgg ctacagtaaa agctatggcc catgtaaata atataccaat aatagcagta
    46861 aattctttgg aatctctagc aaataacata aatttctgtg atagaaagat atgttgtata
    46921 ttagatgcgc agaaaaatca agtttattca gctaaataca agtttgaaaa tggagagatg
    46981 atagaattag atggtgttga tgttgtagat tttgatgctt tagtagatga aattgtatca
    47041 actaatgaag aatttataat agttggagaa gctgtataca aatataaaga caagttagag
    47101 aatataaaaa atataaaaat accttcacca gctaataatg tatctaacgc aggaagctta
    47161 tgctctttag cattaaataa atataataaa aatatagatg tacatacttg ttatacgata
    47221 aatcctatgt atatcagaaa atctcaagct gaagtacaat atgatgaaaa aatgaagagg
    47281 ctaaataatg gaagataata caaaactaat agtagatgat ataaaaatag aagaaatgac
    47341 tacagaagat atagatgaag tttttgaagt agaaaaaaat tgttttgaag attattggtc
    47401 aaaagagtct tttagaaaag agttgtctaa tgaagtagca aggtatatag tagctaagtt
    47461 aaatggaaaa attgtcggat atgtgggaat ttggcttata cttgatgaag ggcatataaa
    47521 taatgtggct gttcatagtg actatagagg gaaaaaaata ggggacaagt tgataaaagg
    47581 catagttgat ttatgtaaag ataataatat tgcatctatg acattagaag ttagagcatc
    47641 aaataaaata gcacaaaatt tatatagaaa atatggattt aaaatgggtg gaataagaaa
    47701 agaatactac agtgataata aagaagatgc aattataatg tggaaccaat taaaagaggt
    47761 gtagagttta tgagtgatat aataacatta gctatagaga gtagttgtga cgaaacagct
    47821 gcatcagttt taaaaaatgg tagagaaata ctttcaaaca taatctctac tcaaatcgag
    47881 acacataaaa aatttggtgg tgtagttcca gaagtggcct caagaaaaca tgtggaaaat
    47941 attgatatag ttgttcaaga agctttagac aaagcaaata taggttttaa tgatatagac
    48001 catatcgcag ttacatatgg acctgggcta gtaggtgctt tattggttgg tctatcttat
    48061 gctaaagcac ttgcatatac tttgaatatt ccacttgtag gagtaaatca tatagaaggg
    48121 catctaagtg caaactatat agagcataag gatttaaaac ctccttttat aacattaata
    48181 gtatctggag gtcatactca cttggttgaa gtaaaagatt atggcaagta tgaaatttta
    48241 ggaaaaacaa gagatgatgc atctggagaa gcatttgata agatttcaag agcgatgaat
    48301 ttaggctatc caggaggtcc tattattgat aatctggcca agaatggaaa taaacatgct
    48361 atagaatttc caagagccta tttagaagaa gatagctatg attttagttt tagtggatta
    48421 aaatcttctg tattaaatta tctaaatgga aaaagaatga aaaatgaaga aatagtagtt
    48481 gaagatgtag cagcatcttt ccaagaggct gtagtagagg ttttatctac taaagcacta
    48541 aaagcagtaa aagacaaagg atacaatatc ataactcttt ctggtggggt tgcttctaat
    48601 tcggggctta gagctaaaat aacagagctt gctaaagaca atggtattac tgttaagtat
    48661 cctcctctaa ttttatgcac agataatgca gctatgatag ggtgtgcagg atattataat
    48721 tttataaatg ggaaaacgca tgatatgagt ttaaatgcag ttccaaattt aaagataaat
    48781 cagtagagtt agatgaattt gtaaatataa aagtattgtt tcaaaaaagt aagtagaagt
    48841 gaaattaaat ataataaaaa taaatatagt atatattaaa acttgaagta aaactattta
    48901 taatctttat attccaatga attgcaacaa attttaggat atacagattg tctttggctt
    48961 agatttgctt caagtttatt tttttctata gaaagattat tttaaaaagt gggtaatata
    49021 cccttttttt tcattcttaa aaagttttat actaattata gaaagattaa ggaggggaag
    49081 aaatgagtca aagtaaagaa gacaaaataa gaagtatttt ggaagcaaaa aatattaaat
    49141 caaattttca aaataaagaa aatttaagtg aatttaatga aaaaaaagca agtaaaagag
    49201 cagaagactt attagatgta tattataata cattatctac tgctgatatg gaatttccat
    49261 attggtataa tagagaatat agaaaatcag atggtgatat accagtagtt agaagagcta
    49321 aagctcttaa agctgctttt tcacatatga caccaaatat aatacctggt gagaaaatag
    49381 taatgcaaaa gacacgccat tatagaggtt cttttccaat gccatgggta agtgaaagtt
    49441 tctttgttgc tcaaggagaa caaatgagag aagaggcaaa gaaattagcc agtaacacag
    49501 ctgatgaact tacaaaattt gggtctggtg gaggaaatgt tactgaaagt tttggaaatg
    49561 tcgtttcaat agctggtaaa ttcggaatga gaaaagaaga agtacctgta cttgtaaaaa
    49621 tggcaaagga atgggttgga aagtctgttg aagatttagg ttttcactat gaaaaaatga
    49681 tgccagatta tgatttaaaa gaaaacctaa tgagtacact tatatgcatg tttgattcgg
    49741 ggtatacact tcctcaaggt agagaagtta taaattattt ttatccttta aattatggat
    49801 tagatggaat tatagaaatg gcaaaagaat gtaaaaaggc agttgcagga aatgcatctg
    49861 gagatgggct tattggtatg gaccgtctat atttttatga ggctgttatt caagttattg
    49921 aaggattaca aacttggatt ttaaattatg caaaacatgc aaaatattta gaaagtatag
    49981 agacagattt agaagctaaa aaagaatact cagatttagt ggagatatta gaacatattg
    50041 cacataaaca acctcgtaca tttagggaag ctcttcagtt gacttataca attcatatag
    50101 catcagtaaa tgaggatgct atatctggta tgtctatagg acgttttggt caaattttat
    50161 atccttggta tgaacaagat atagaaaaag gactaattac aaaagaagag gttatcgaat
    50221 tattagagct ttatagaata aaaatcactt gtattgactg ttttgcttca gcgggggtaa
    50281 atggaggagt actatcaggt aatacattta atactttatc tataggtgga ttaaaagaag
    50341 atggttctac aggagctaat gaactagaag agttattatt agaagcaagt atgagatgta
    50401 gaactcctca acctagttta actatgctat atgatgaaaa gcttccagaa gatttcttaa
    50461 tgaaagctgc tgaatgtaca aagcttggtt ctggttatcc agcatgggta aacaactcaa
    50521 atggaacaac atttatgatg aaacaatttg ctgatgaagg tatgactgtt gaagaagcaa
    50581 gagcatttgc attaggtgga tgtttggaaa cgtctccagg gtgttggaaa cagttaactt
    50641 taaacggaaa aacgtactct attgcaggtg gagcaggtca atctgctggc tctggagttc
    50701 actttatagc taatccaaaa attttagaac ttgttcttat gaatggtaaa gactatcgta
    50761 tgaatataca agtatttgag cctcataata agccattaga tacttatgaa gaagtcatag
    50821 aagtatttaa agattattat aaacaagcaa taaatgtttt agaaagagca aataacattg
    50881 agttagatat atggagaaaa tttgatactt ctataataaa ttcactacta aagccagact
    50941 gtttagacaa aggtcaacat ataggaaata tgggatatcg ttataatgca acattaaacg
    51001 tagaaacttg tggtactgtt actatggtca attcatttgc agcgcttaag aaacttgtat
    51061 atgatgacaa agcatttaca atagaggaaa ttaaggatgc catattaaat aattttggat
    51121 ttaaagatgc attagaagta ggaaattatt ctatggcaga ccaagtaaaa gtagataaga
    51181 ctggtaaata tgatgctatt tataaggcct gtcttgatgc acctaaatat ggaaataatg
    51241 atttgtatgc agataatatt cttaaaaact atgaggtatg gttatcaaaa gtatgtgaag
    51301 aagcacaatc tttatatgct aagaagatgt acccttgcca aatatctgtt tctacacatg
    51361 ggccacaggg agctgctacc ttggctactc cagatggtag actaagtgga acaacatatt
    51421 cagatggttc agtctctgca tatgcaggaa cagataaaaa tggagtatat gcattatttg
    51481 aatctgcaac tatttgggac caagcagtag ttcaaaattc tcagatgaat ttaaaacttc
    51541 atccaactac tataaaagga caacaaggaa ctaaaaaatt attagattta acaagaagtt
    51601 atttaagaaa aggtgggttc catattcaat ataatgttgt agattcagaa accttaaaag
    51661 atgcacaaaa aaatcctgac aattatcgtc aattaatggt acgtgttgct gggtttactc
    51721 aatattggtg tgaattaggt aaaccaatac aagatgaagt aattgctaga acagagtatg
    51781 aaggggtgta aaatatgaga aagcatagtg attgtatgaa tttttgtgca gtagatgcaa
    51841 ccaaaggaat ttgtagatta tcaaaacaaa tgattaattt agatgatgca gcatgtccag
    51901 agataaaagt aatgccaaaa tgtaaaaatt gtaaaaattt tgttgaagct aatgatgaag
    51961 gtataggcaa atgtgttggc ctagagaaag aagattgggt atattcaaca ttgaatgcaa
    52021 ttacttgtga aggacatgtg tttaatgagt agtcaaaagc aattagaagg catgattttc
    52081 gatgtacaaa gcttttcagt tcatgatggt ccaggttgta gaacaactgt atttttaaat
    52141 ggatgtccac tgagttgtaa atggtgtgca aatccagaaa gttggactgt aagaccacat
    52201 atgatgttta gtgaattatc ttgtcaatat gaaaatggat gtactgtatg tcatggtaag
    52261 tgtaaaaatg gtgcattgag ctttaatctt gataataagc cagttataga ttggaacatc
    52321 tgtaaggact gtgaaagttt tgaatgcgtc aactcatgtt attataatgc gtttaaatta
    52381 tgtgcaaaac cttacactgt agatgaactt gtgcaggtaa ttaaacgtga ttctaacaat
    52441 tggagaagta atggaggagt aacatttagt ggaggtgagc cactacttca gcatgaattt
    52501 ttacatgaag tattattaaa gtgtcatgag gtaaatgtac acactgccat tgaaacgagt
    52561 gcatgtgtat caaatgaagt ttttaataaa atatttaacg atattgattt tgcatttatt
    52621 gatataaagc atatggatag agaaaaacac aaagaacaaa caggtgtgta taatgattta
    52681 atattagaaa atatatcaaa ccttgcaaat tctgattgga atggaagatt agtacttaga
    52741 gtaccagtta tctctgggtt taatgatagt gatgaaaata taagtgatat tatatctttt
    52801 atgcacaaaa ataatttggt agaaattaat ctattaccat ttcacagatt aggagaatca
    52861 aaatggactc aattaggcaa ggaatatgag tattctgata agggtgatgt tgatgaaggt
    52921 catcttgaag aattacaaga tatatttttg gataatggta tagcttgtta tgttggtcat
    52981 gagacagctt tctaaaatta aatacaagtt ttaattaaaa aaggatgtta cactaaaagc
    53041 tagagttaca tcctttttta tgtggttttt atgtagaaat aattaagtaa agttttatat
    53101 gttttatata ttgtttatat tgctttatgt ccataaatat tgctttaaat atactttata
    53161 tattttttat agtttaaatt acagttagag aatatattac gtttacttta ttgaagcaga
    53221 agttttgtgg taaaatacta ctatgaaaaa atttaataga atatatttta gaaacaacta
    53281 aaaataatag ttaggaggaa gacatctata tgaacaaatc atggagcaac ttgattatta
    53341 agaataaaga cagaaaagta cgttcagggt ggattattat agctgttatg gctacctttt
    53401 acatacttca gtattattta agcatgatac ttgtggaaat aataagaaaa atcctggttg
    53461 ctacaggtga cattaattta aaaacaaact atttttcaga atatgctaat tggttaaatg
    53521 atgttgggtt acagattgta tttcaaattc taacagattc acttatgatt attattccta
    53581 taattgtatg gagatttatt atgaaaaatc ctattagtga aatgggatta cattcttata
    53641 gaattaagaa aaaagaagga tatgtaggaa tgttattagg aatatttaat tgtacagtaa
    53701 tctttattat aacaataaca attggtggtg gtcatgttac ttcatgggta ccaaaaattt
    53761 cacctttaac agtttcttgg atactggtct ttattttagt tgcttttgca gaagaaattt
    53821 taaatcgtgg tttttttatg gcagttttac gaagatgtaa aaatatttat tttataatga
    53881 ttgttccatc tgttattttt gggttgattc atatatggaa tcctgatgtt acttttttgt
    53941 ctgtaattaa tattataatt attgggattc ttttttcata tatgtttata aagtcgtcga
    54001 atatatggat gtgtataggt tatcatttta catggaatgt atttcagggg attatatatg
    54061 gtatgcctgt aagtggactt caggttccag ggattataac tacacaaatc actcatggta
    54121 atctattaaa tggagggatg tttggtattg aaggtggaat tttgactact tttgttaatc
    54181 tacttagctt tatatttgta tggtattact atagagattc taagtatgat tttgttagtg
    54241 ataaagtaaa tgtgaccaat atcaagaatt agttgattat aataaatttt aataatatct
    54301 tctaagctta aagtattctg taggattgtt ggaaatttgc aaaaatataa aaataacttg
    54361 gatattctat ttactccaag ttatttttat attcttttgt aaatagaaat ggaacataaa
    54421 aaattaaaac aaccatagat actattagta tatcatggta agtgatagtt gattctttag
    54481 aatttgtgat aagaaaagca ctattattta aaacatgaat tatagcacaa aaccagatat
    54541 tcttagtttt tatataaaga tatcctaaaa atattgaaat tccaactata tgtattgaac
    54601 gtaatattat tcctaatatt ggcgcttcag gtgtatataa tgtaaatatt agtggtaagt
    54661 gccacaagct ccaacacata cctaatatta taactcctaa ctttttacca aatttatcaa
    54721 aaaaaatatt ctgtaaaaaa cctctccagg catattcttc actaaaaaaa atataaatag
    54781 tagttaatga tgttattgga gtaaatataa attttatgat accactataa ttaggttgag
    54841 ccccttgtag tattagtata aatgatgttg gaacaattac agaaatcata aagtaaataa
    54901 ttaataaaga acctagttta atatttttta caggatataa atttttttta tttgatgaat
    54961 atattataat tgataagcta cttataaaaa ttaatattag gtttataatt ataaattcat
    55021 tattatttat tagatttaat aacttaagaa caattaataa tgaataaata agaaaaaata
    55081 atatgattag tgaataaaat tcatacatat cattatttaa tccttcagta taaaactttg
    55141 caatagcaac tgaagataga ggtaatatca tcatgaatga tgcaaagttt tctggatcaa
    55201 taaatttatt ataatataac agtaaaccta atgaataagt taaatcaaag tttataaaga
    55261 aaaagataat aatttgtatt ttttttcttt ttatttcatt tttaataaat actgggttta
    55321 gaatatttat ccatattaat tttaagttca ttaatttaat actcctttac aatataga
//
LOCUS       DAEOTL010000016        52645 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.016, whole genome shotgun sequence.
ACCESSION   DAEOTL010000016 DAEOTL010000000
VERSION     DAEOTL010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.016"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            52..768
                     /locus_tag="KRH82_001288"
     CDS             52..768
                     /locus_tag="KRH82_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654578.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMLGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            865..1128
                     /locus_tag="KRH82_001289"
     CDS             865..1128
                     /locus_tag="KRH82_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654579.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            1100..1555
                     /gene="def"
                     /locus_tag="KRH82_001290"
     CDS             1100..1555
                     /gene="def"
                     /locus_tag="KRH82_001290"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBG8654580.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            1607..2068
                     /locus_tag="KRH82_001291"
     CDS             1607..2068
                     /locus_tag="KRH82_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBG8654581.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            2118..3020
                     /locus_tag="KRH82_001292"
     CDS             2118..3020
                     /locus_tag="KRH82_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8654582.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            3390..4202
                     /locus_tag="KRH82_001293"
     CDS             3390..4202
                     /locus_tag="KRH82_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8654583.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            5249..6010
                     /locus_tag="KRH82_001294"
     CDS             5249..6010
                     /locus_tag="KRH82_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBG8654584.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLARILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            6075..6857
                     /locus_tag="KRH82_001295"
     CDS             6075..6857
                     /locus_tag="KRH82_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBG8654585.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKGKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            7124..7543
                     /locus_tag="KRH82_001296"
     CDS             7124..7543
                     /locus_tag="KRH82_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBG8654586.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(7646..7912)
                     /locus_tag="KRH82_001297"
     CDS             complement(7646..7912)
                     /locus_tag="KRH82_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBG8654587.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            8139..8840
                     /locus_tag="KRH82_001298"
     CDS             8139..8840
                     /locus_tag="KRH82_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654588.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            8922..9530
                     /locus_tag="KRH82_001299"
     CDS             8922..9530
                     /locus_tag="KRH82_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBG8654589.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            9838..10302
                     /locus_tag="KRH82_001300"
     CDS             9838..10302
                     /locus_tag="KRH82_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 domain-containing lipoprotein"
                     /protein_id="HBG8654590.1"
                     /translation="MKKLVISLISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNACLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNIWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            10939..11955
                     /gene="gap"
                     /locus_tag="KRH82_001301"
     CDS             10939..11955
                     /gene="gap"
                     /locus_tag="KRH82_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBG8654591.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            12350..13519
                     /locus_tag="KRH82_001302"
     CDS             12350..13519
                     /locus_tag="KRH82_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654592.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            13900..18153
                     /locus_tag="KRH82_001303"
     CDS             13900..18153
                     /locus_tag="KRH82_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBG8654593.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATEEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            18302..18796
                     /locus_tag="KRH82_001304"
     CDS             18302..18796
                     /locus_tag="KRH82_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBG8654594.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            18912..19289
                     /locus_tag="KRH82_001305"
     CDS             18912..19289
                     /locus_tag="KRH82_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBG8654595.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            19495..19935
                     /locus_tag="KRH82_001306"
     CDS             19495..19935
                     /locus_tag="KRH82_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBG8654596.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            20577..21884
                     /locus_tag="KRH82_001307"
     CDS             20577..21884
                     /locus_tag="KRH82_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654597.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEVFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    21970..22232
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            22358..23161
                     /locus_tag="KRH82_001308"
     CDS             22358..23161
                     /locus_tag="KRH82_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8654598.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPNNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            23199..23810
                     /locus_tag="KRH82_001309"
     CDS             23199..23810
                     /locus_tag="KRH82_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBG8654599.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            23842..24513
                     /locus_tag="KRH82_001310"
     CDS             23842..24513
                     /locus_tag="KRH82_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBG8654600.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            24812..25174
                     /locus_tag="KRH82_001311"
     CDS             24812..25174
                     /locus_tag="KRH82_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBG8654601.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            25610..26311
                     /locus_tag="KRH82_001312"
     CDS             25610..26311
                     /locus_tag="KRH82_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBG8654602.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            26582..27400
                     /gene="larE"
                     /locus_tag="KRH82_001313"
     CDS             26582..27400
                     /gene="larE"
                     /locus_tag="KRH82_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBG8654603.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            27455..28603
                     /locus_tag="KRH82_001314"
     CDS             27455..28603
                     /locus_tag="KRH82_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBG8654604.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            28747..30135
                     /locus_tag="KRH82_001315"
     CDS             28747..30135
                     /locus_tag="KRH82_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8654605.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            30164..30862
                     /locus_tag="KRH82_001316"
     CDS             30164..30862
                     /locus_tag="KRH82_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654606.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            30865..32298
                     /locus_tag="KRH82_001317"
     CDS             30865..32298
                     /locus_tag="KRH82_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654607.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            32320..33057
                     /gene="truA"
                     /locus_tag="KRH82_001318"
     CDS             32320..33057
                     /gene="truA"
                     /locus_tag="KRH82_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBG8654608.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    33168..33375
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33628..34827
                     /locus_tag="KRH82_001319"
     CDS             33628..34827
                     /locus_tag="KRH82_001319"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBG8654609.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWNIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            35074..36120
                     /locus_tag="KRH82_001320"
                     /pseudo
     CDS             35074..36120
                     /locus_tag="KRH82_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
     gene            36228..37391
                     /locus_tag="KRH82_001321"
     CDS             36228..37391
                     /locus_tag="KRH82_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8654610.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAQAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNHSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(37480..37860)
                     /locus_tag="KRH82_001322"
     CDS             complement(37480..37860)
                     /locus_tag="KRH82_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBG8654611.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(37863..38522)
                     /locus_tag="KRH82_001323"
     CDS             complement(37863..38522)
                     /locus_tag="KRH82_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBG8654612.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(38628..39602)
                     /locus_tag="KRH82_001324"
     CDS             complement(38628..39602)
                     /locus_tag="KRH82_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBG8654613.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGVLVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(39642..39989)
                     /locus_tag="KRH82_001325"
     CDS             complement(39642..39989)
                     /locus_tag="KRH82_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654614.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(40207..41163)
                     /locus_tag="KRH82_001326"
     CDS             complement(40207..41163)
                     /locus_tag="KRH82_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBG8654615.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            41606..41974
                     /locus_tag="KRH82_001327"
     CDS             41606..41974
                     /locus_tag="KRH82_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBG8654616.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            42399..42644
                     /locus_tag="KRH82_001328"
     CDS             42399..42644
                     /locus_tag="KRH82_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654617.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
     gene            42743..43006
                     /locus_tag="KRH82_001329"
     CDS             42743..43006
                     /locus_tag="KRH82_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBG8654618.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(43291..44238)
                     /locus_tag="KRH82_001330"
     CDS             complement(43291..44238)
                     /locus_tag="KRH82_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBG8654619.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(44241..45872)
                     /locus_tag="KRH82_001331"
     CDS             complement(44241..45872)
                     /locus_tag="KRH82_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBG8654620.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGTLFYPNLKVMEE"
     gene            46002..46919
                     /locus_tag="KRH82_001332"
     CDS             46002..46919
                     /locus_tag="KRH82_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8654621.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(46976..47557)
                     /locus_tag="KRH82_001333"
     CDS             complement(46976..47557)
                     /locus_tag="KRH82_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8654622.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(47597..48163)
                     /locus_tag="KRH82_001334"
     CDS             complement(47597..48163)
                     /locus_tag="KRH82_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8654623.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            complement(48599..49459)
                     /locus_tag="KRH82_001335"
     CDS             complement(48599..49459)
                     /locus_tag="KRH82_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8654624.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            49608..50498
                     /locus_tag="KRH82_001336"
     CDS             49608..50498
                     /locus_tag="KRH82_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8654625.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLIPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPPNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            50716..52470
                     /locus_tag="KRH82_001337"
     CDS             50716..52470
                     /locus_tag="KRH82_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBG8654626.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKAIRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKNYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT        20816 a         5598 c         8575 g        17656 t
ORIGIN      
        1 aacttattat tttatttgta gcagttggaa aaaggtaggt ggagtaaaac tatgataaag
       61 attataaatg cgtttaaaca agagtttgaa caaattaaga gagatgctat gctttttata
      121 gtatgtgttt ctccaatatt atgtggagta tttataaaat ttggaatacc attaatacag
      181 aatatatcac ttaacaagtt ttattatcaa ttaaatttag agccgtattt cttgatgttt
      241 gatttacttt tagcttttat tacacctttt atgttctttt ttgcttctac aatggtcata
      301 ttgggagaaa ttgatgacag catttcaaga tatttaatag taactccgct tggtaaaact
      361 ggttatctta tttcacgatt tggaatacca ggtatcttag catttattat tactatgatt
      421 ctacttatct ttttttctct aactaaaatt tctttcttgt taaacttatc aatttcttta
      481 ttagttttat tacaaggaat tattatatca atattagtga tttctttatc atcaaataaa
      541 ctagaaggaa tggtaattac gaaattctca ggtgttttta tgctgggtat tttagcacca
      601 ttttttattt taaataaagc acaatatatt ctgttcttct taccaacttt ttggatatcg
      661 aaggcattta aggaagataa ttatatctat atgtttattt caattgttat atcattaata
      721 tggattttat tattatttaa aaagtttagt aaaaaaatag ttaaataaga aaatttaata
      781 tataaatgta aggttgactt gacagtaatg ttgaaaaatg ttacatttaa gatgtaaagt
      841 taaccttaca tgaatggagc aaatatgaaa aataaaataa agatattaag agaaaaatta
      901 ggattgacac aagaacaact agggagatta gttggaacat ctagacaggc tataaatgct
      961 atagaaactg gtaaaaatga accttcaata tggttggcat atgatatttc aagaattttt
     1021 aatgaaccaa ttgaaagtgt atttttattt gaagaaagtg aaagaaaatc aagagcacag
     1081 ataagtaggg gagaatatta tggctataag aaagataaga acatttgatg atgaaatttt
     1141 aagaaaaaag agtaagtatg tagaaaacgt agataataag ataagagaaa tattaaatga
     1201 catggcagag accatgtaca atactccaaa tggaggagga ttagctgcat gccaagtagg
     1261 agtattaaag cgattagttg ttatagattt aggagaagga cttattaagc ttgttaatcc
     1321 tgaaattatt aaacaagaag gggaacaaat tgttgttgaa ggatgtttaa gttttcctga
     1381 agtatggggt aaattaaaaa gaccaaaaaa agttacagta caagctctaa acgaatacgg
     1441 tgagaaaata gaaattaaag gttcaggttt tatggcaaaa tgtctttgtc atgagataga
     1501 ccatttaaat ggtatagttt ttacagataa aattattgaa catgtaaaat tgtaagatag
     1561 attggttatt gaatttataa aatattttat agtaaggagt taaattatga gattatggca
     1621 taaggattta attgatgtat tacctaaaaa tcaattagta agtcaatgga gagagctact
     1681 tgctataaaa ggttctatag ataaaaaagg tactccaaac catctattag tgaataaagt
     1741 attgaattat agtatagatg aatttaaatt ttatacaaaa attgtacatg atgaaatgtt
     1801 aaaaagaaat tataaaccta atgaacttaa atatacaagt atattaaaat ggaaaaatag
     1861 aaattttgca aatgatatat ctaatgaaca tagtttaaat ttagaaaatt tatatgatga
     1921 ttggcataat aaaatgtatt taaagcaatg cttatataat ttagaagaaa aagcaacatg
     1981 tggaggaata ccaataaatg aatggaatat attactttgt aaatatagta aagattatga
     2041 attgtggtct ggaaatatca tgttttaatt actatagatt aacattatag tattattgta
     2101 tataaagagg tgattatttg tataataaaa taaaatatat tccaataaat tgtgaaatag
     2161 cttgtaataa attaaaaagg agtatgccat ataaatggga tttaaatatt tatcgtggat
     2221 gtgagcatgg atgtaaatat tgttatgcta tttactctca taagtacatc aactccaata
     2281 attattttga agagatttat gtaaaaacaa atatagtaga aaaacttgag agacaactta
     2341 aaagcagtaa atggaagaaa gaagtaatca atataggagg agttacagat agttatcaac
     2401 caatagaagc tgactataaa attatgccag aaatattaaa cctgctgata aaatacaaga
     2461 caccagctat tatttctaca aagtcagatt taattttaag agattacgat ttaattgata
     2521 agctatctag gattacatat atcaatgtag catctacaat taccacagta aatgaagata
     2581 cacaaaggct tattgagcca aatggtgtgg attcaatgag acgatttaaa atgttaaaag
     2641 aatttagaaa aactaacgca tcagttggtc tacatattat gccaattata ccatatatta
     2701 cagatgattt tgataatata aattcgctat ttagacatgc aaaagaatgt aatgtacatt
     2761 atgttttacc tgggacttta tacttaaggg gtataactag aggtgttttt tttgactttg
     2821 ttaaaaaaga gtttcctgaa ttatttgata aattatcaat actatatagt gcaggttcac
     2881 ttaataggga gtataaaaat caattgtata aaatggttaa tgaacttaga tataagtatt
     2941 ctctatcaag cagttactct aaaataatga aggaaaagtt aaaaaactca ggagatgtac
     3001 agatatcttt ttttgattag ttttatataa aaaaaatttt tttactatga tgattaaaat
     3061 ttattaaaat taaaatttat tgacaaatat aaaatttaaa tatataatta attcataaaa
     3121 taaaaatatg aaaggatgat gttgttcggt gatatttgat atcataaaat cgttgatata
     3181 agtattgctg gaaaagagtg aataaaatca aatttaataa gcaaacaaag taaagctata
     3241 gttttattgt tgtgcttaaa aatatttggt tctattttac tcttatttaa actcatcttt
     3301 ttgaagttaa accacagagt aaactctgtg gtttttttat tttaaaaata aattttaagg
     3361 agtggtatgt tttgttaaac aaattatgta tgtatttaga aagaccagag ctttataaac
     3421 aaagtgaaat taatttttgg gatgatgagt atatttcaaa gcaattatta aaagcacact
     3481 tagacactaa ttttgaagga gcaagtagaa attttaactt tatcgaggat tctgtaaatt
     3541 ggatagttac agttgcaaat ccagctaatt atcctaaatt acttgattta ggttgtggtc
     3601 caggtttata tgcagagaaa tttgcacaaa aaggttataa ggtaactgga attgatttct
     3661 caaaacgttc tattaactat gcacaaaata gaaataagga gactaattta aacataaatt
     3721 acttgtttca aagttattta aatatgaact ataatgagga atttgatttg gctaccttaa
     3781 tttattgtga ttatggagct ttgtcaactg aaaatagaag gttattaatg gaaaaaattt
     3841 atgatagttt aaaacctgga ggaaaattaa tattagatgt atttacaata aataaataca
     3901 ataattttga ggaaattaaa tattgggaaa taaatgaaga tggaggattt tggagtaatg
     3961 aaaaatatat gtgtctacaa gataattgta aatacaatga ttataataca ttagaacaaa
     4021 ctcttgtaat aaccgaaaaa gatgaaaatg tattttatgt ttggaatcac tatttttcaa
     4081 aagaaagttt cttattagaa gttgaaaata ttggatttaa gtctgttgag ttttttagta
     4141 atgttaaggg tgaagcatat tctgacgata gtatgactat gggattagtt ttacaaaaat
     4201 aataattttt ttaaaatgaa taaataaaaa cttgaaacct ttaacaataa aataacataa
     4261 taaaagctta catattgaaa aatggaaact tttatgttat ttttagtaca ttacaaattt
     4321 gcttatataa aaatcaatac ttgaattatt atttttatgt gaaatttatc tatagtatat
     4381 ttttataaac aagtaatgtt attaaaatta agtatatagt taaaagtgta tagcaaaaag
     4441 gctgttatat taatgttaga ggttcaggga aaatatataa agcaaagtat ttacagataa
     4501 tgtagattgc acagctataa gttagataat agaattatgt aatcaagaat ttacaacaaa
     4561 gtataagata aggataatgc taaattgcca tacaggtgct agatgtgtaa atggatttaa
     4621 ttaatactat tgataaagtg caacaagcac ataaaccaat tgatgagatt attaaaacta
     4681 taagagatat agttgacata attaaaatat tggaacctat ttataatttt aaatcaaatc
     4741 aataatgatt aagattaaaa taatattaag gcatcaatgt tataagagta caatataagg
     4801 agtactatat agtactcctt acttatacat attaggcaat aggaaatttt tcatagttaa
     4861 attttcaaat attttttagg gaactttata attgagaatt aagggtatag tatgtgatga
     4921 acttactaaa tttataatta ggttatataa tggaataatc atcaatagtt ttactttagg
     4981 gaaaatatat gcttaaggaa gtatagctta ctaatattat taaaatgtat atttaaaatg
     5041 ataaaaaaag aattagacaa gtatttagta aattgactat gcaaaattct atcaagcagg
     5101 aacactatga ctttagtcat gggaggttca gtaggtaact tgttgaatta agtttatatt
     5161 atttaaataa actacttaat ttagataata taaaaagtca gaattttaag aatagagcta
     5221 tataatctta gctattagga gaagtactat gataggaata tattttagtg gaacaggaaa
     5281 ttcaagatac tgtgtagaaa aatttttaca agaatatgat ataacagcaa attcttattc
     5341 tattgaagat aatgaacttt tacagcacat caataatcat gagaatatta tttttagtta
     5401 tccggtgcaa tatagtaatg tgccaaaaat attgaaagat tttataataa atcattcaac
     5461 tttgtggaat ggtaaacgtg tttttattat tgcaactatg gctctattta gtggagatgg
     5521 ctctggtgtg ttagctagaa tattaaaaaa atacggtgct ataactgttg gtggattaca
     5581 tgtgaagatg ccagatagta taggagatga aaaggtatta aaacattctt tagagtataa
     5641 tagaaagctt gtaataaaag cagaaaagaa agtaactaag gctgctaaaa aactgaaaca
     5701 tgggtcacca ccaaaagaag ggttgggttt tttgagtcat attgtagggt tatttggaca
     5761 acgattgtat tttatcaata aaacaaatat gtatacagat aaactaaaaa ttaatactga
     5821 ggaatgtatt gtatgtggta aatgcgttaa tttatgtcca atgaagaatc tagtaattaa
     5881 aaattgtatg attgttgcaa atgggcaatg tacaatgtgt tatcgttgtg taaataattg
     5941 tgccaaaaaa gcaattacat tgttaggtaa aaaagttgtt gaacagagta atattaagaa
     6001 atatatgtaa gaaatttaaa gttttattga atgtaaattg atgtatattt tatgttagaa
     6061 agagaggtta aataatggaa tactacatag ttgattcatt tgcaactaaa ctatttaaag
     6121 gaaatcctgc tggagtttgt gttcttgaca gaagaatacc tttagagtta atgcagaaaa
     6181 tagcagaaga aaacaattta ccagaaacag catttgtagt taaaggtaaa ggaaattatg
     6241 aattacgatg gtttactcct aaagcagaaa ttgatttatg tggtcatgca actttagcag
     6301 cagcttatgt aatatcaaat tttattgatg ttaatgtaaa aaggatagat ttctttactc
     6361 aaagtggaaa gcttgaagtt acacgaaatg gaaatctata tgaaatgata tttccagaaa
     6421 taatgcctat tgaaatagag ttatcaccac aacaagctaa tttgataggc tgtgtaccaa
     6481 gtgctgttta ttcttcaaga gatttaatct tattgctaaa cagtgaacaa gaagttataa
     6541 attataaacc taattacgca caattgcgta aattgacaga ctggttaggt ataataatca
     6601 cagcacaagg aagtaataca gattttgtat caagatattt ttgtccagaa ttagattcag
     6661 aagaccctgt tactggttca tcacattgta atcttattcc atattggtct gaaaagttgg
     6721 gaaaacacaa aatggtagct gctcaacttt ctaatcgtgg tggtataatt cagtgtgaag
     6781 tgttgaagga taatactgta aaaatttctg gtgaagcagt cttgtttatg cagggaacaa
     6841 taaagattga tatttaaata agtataataa ctaatttatt atgaaaaata attaattttc
     6901 ttagtgttaa caataataaa gtagagttaa aaaacttgat ttcacttaaa tcaatatgat
     6961 agatgttgat actaagattg acaagcatga ttaaaaaaga taatatttaa tctataaaga
     7021 taaaaacaca gtctggttgg tagtccagac gcagcaatag ctgtcagtaa cctgcctcct
     7081 tggttgtccg ttctttagaa agtaatttaa ggaggaacta gcaatggaca aaattagtgg
     7141 aaaattaaca gtcttatttg aagaaccatt ttgggtaggt atatttgaaa gacaagatgg
     7201 taaaaaatat gaagcatgta gggtagtttt tggagcagaa cctaaagaag tagaagtgta
     7261 tgaatttata cttgaaagat ttttctcatt agattttggt agcattaaat tagaaaaaaa
     7321 tgtgaccaaa gacaacattg gatacaaaag aatgcagaga aaagtaaaaa aggaacaaga
     7381 aaaagaaact atagggacta aggctcaaaa tgctcttaag cttcaatatg aagaaagaaa
     7441 acaggataga aaaaacctag ctaaaaatag aaaagaagaa gaaaaagaaa gactatttaa
     7501 tttgaaacaa gaaaagagaa aagctaaaca taagggtcat taattttaat taaatatctt
     7561 tttaataatt gctagaaaaa ggtgtataaa atttttaatt ttatacacct taatttattg
     7621 aaaagaataa ggttttatat ttcaattact ttaaaatata aaaatatact aataaaaatt
     7681 gtaaaaatag tataaatggt ataccaaatg taaatttaat gtgtttagtt ttatgtctaa
     7741 aagaatacat tccaattata gaacctatac tacctccaat tactgctata gacataagag
     7801 tagcttcttt tattctccat tcgtttctaa ttgctctttt cttatctatg tacattgaaa
     7861 agaaagcaat agaattaatc actataaaat atattagaat aaaatttttc acagtcttgc
     7921 ctccataaaa atatattata cattataaaa caagatattt gttttggaaa gttaaatttg
     7981 taattagtac atataaaata tttgataaga ataaatataa tattaattgg aaaatttaaa
     8041 aaaattaaac aattagcaaa tagggggtat atttataaga cacaaagtga taaaatctat
     8101 ttagaaaata atgtaaaata acaggaggat aaagcaaaat gaaatttata gtagaaaaag
     8161 aagtttttga taaattagaa aatgtatgct ttggtgtagt agttgcaaaa ggaatagata
     8221 atactaaaga aatagaaaga ataagcaacc ttttagatat aagtatagat agagtagaag
     8281 attacttcaa agataaaaaa gtaaaggaat cagaagaaat tataccatat agagaggcat
     8341 ttagaagtct aggcatgaac ccaaataaat ttatgagttc gatagaagca atgacaacaa
     8401 gggttgctaa gaataagaaa cttcctcata taaatcctat tgtagattta ggaaactcta
     8461 tttctttaaa atatttactt ccaatgggcg ctcatgatat ggattttaga aatgatgatg
     8521 tatatgttag attttctaaa aaaggggata aatttgtacc atttggagaa actgatgttg
     8581 aattaatgga agaaggagaa ttaatttatt cagttggaga catggtaaaa actagaagat
     8641 ggatatggag acaaggagag gaaggaaaaa ttactaatag ctcaaaaaat atattttttc
     8701 ctatagatgg ttttactgat gctaatttag ataaggtaat gagtgcaaga gaagaattag
     8761 caaaattgtt aaaggaaata tttaattgtg aaattaaagt aggttttgta gataaagata
     8821 atcctgaaat ggaaatataa taagttgttg aatacttgtt aagatattat atttacttaa
     8881 taatgttaaa aaggtattaa aaaagaaagg tcgtagtaaa tttgaaaaaa actataataa
     8941 agaatgtaaa tccaatgatt gaaaataagt ttataggact ttttgaaata gagtataaaa
     9001 acaaattaga tgaagataag gtttggatgg tagcatcaag aaaaagtagt gagcaattaa
     9061 aaaatattta tttgaagaat gaagaagata gtgtagatgc agttgtaata gttgggcttc
     9121 ataaaagtag taaaaaatta attttaataa gacaatttag agtacctatt aatggatata
     9181 tatacgagtt accagcaggt cttgttgatg aaggagagtc tatagatatt tccgttgaaa
     9241 gagaacttag agaagaaaca ggacttactc ttttagaaat taaaaaaaat aaaagtattg
     9301 ataaagttta tttatctcct ggaatgagtg atgaatctgt tgcctttgtt tattgtatat
     9361 gtgatggtga tataacagat gaatttttag aaccagatga agagattgaa gcgcttttaa
     9421 tttcgcaaga agatgcaaaa gagattttac aaagtaatca taagatagac acaaaagcat
     9481 ttttgatttt acaaatgttt gtgagtttag gagctaaatt atttgaatag atatatagaa
     9541 aagtaaaata ataaagttta ttttacttgt ataaattata atctcttttt ttatacaata
     9601 aagtataatt ttgtgtattt ttaaataagt gacttgactc ttaaattttc ataatatgtt
     9661 ataaaccaat ttaagatact acaataatta aaattccaaa attatttaac atatttgcaa
     9721 ttaaaatgag aaaaggtaaa ggctgaatga ttgaaaaatt tgatgtaaaa tagtagatta
     9781 gtttaatact atagtttgta gggttaaaaa ttagaaattg taagggagat aaattctatg
     9841 aaaaaattag ttattagttt aattagtatc attagtgtgg ttagcttgac agcttgtaaa
     9901 aaaagcaatg aaagtaaata taataattta aacaacaaag aatcaggaca aacaaccatt
     9961 gaaatggact tagataaaaa ttatgatact tcagacccat ttgttaatgc atgtttgttt
    10021 tgtgtgtcta atgatataga tgttttagac acagagattt cttttaaaat ggatggagat
    10081 agtggtattg tggaaataaa ggacaataaa acagatgaaa ctttatggag taatatatgg
    10141 catggaagcg ttgataatga tacattcgca atttctcttt ctaatataca aaaagagaaa
    10201 gagtatgcta tatgctttac tggaattaaa ataaatcatg cagttgtaaa ggttactttt
    10261 gaaagcaatt tagttaagga gaaagaaaaa ccctcaaaat aaattccaga ttgtctataa
    10321 cttgatattc agtacataaa agcagttgat atttatgatt gactgctttt tcttatcaaa
    10381 aaggataggt tgtgcatttt tacttgaaat agtttatgca catcaaaagt tggtgagcat
    10441 gatattggaa atggtaagca tgaaatcttg ataacacaag gaaataaatt taagttttca
    10501 attaagtata tttccataat ttagttaaca ataagctaat tattatttat attttgatat
    10561 ataaataata attgtagcaa attttaaaaa atcatatatt ttttgaacta aataaaaatt
    10621 tatttttatt attttaaatt agaggagatt cttgaagata tattattttt aaaaataagt
    10681 atagtttaaa aattcaaaaa aaagatggca aaatatgtcc caagggacat tgagtaaaat
    10741 aaatgatttc agcttcttta cactaaaaag tacatactaa atgaggggta aaataaagaa
    10801 aaatgatata ctaattgtct tttgataata aaaaaacatg gaatttgatt atttaatcaa
    10861 gaaaaagtat tgaacaaatg atttatttag tgtacaataa tcatgtaaaa acatagtaat
    10921 ggagggagac atttcataat gaaaattaag gtaggaatga acggatttgg aagaatagga
    10981 agagctgtat taagaatagc tcaagaagaa ttaggagata atatagaaat tgtagccata
    11041 aatgcaagag caacaacaga atctttggca catttattta catatgattc atgctatgga
    11101 acttttagag gtgaagtaga ggcaaaggat gaagacactc tagtagtaaa ctctaaagag
    11161 ataaaaatat taagatataa tgacccagaa gaattacctt ggaaagaatt gggggttgat
    11221 atagtaatag aatcaacagg attatttaca caaagagaaa aggcagaaaa acatattaaa
    11281 gcaggagcaa aaaaagtaat tataacagct ccaggaaaaa atgaagatat aactatagtt
    11341 atcggagtta atgagaaaga atatgataat gaaaagcaca atataatttc aaatgcatct
    11401 tgtactacaa attgtctagc tccttttgct aaagtattgg acgaaaaatt tggtatagta
    11461 aaagggttaa tgactacagt acattcatat actaacgatc aaagaatatt agataaaagc
    11521 cataaagatt tgagaagagc aagagcagcg gctgaatcta taatacctac cactacagga
    11581 gcagcaaaag ctgtgtcaag agtactacca caattagaag gaaaattaaa tggtttttca
    11641 cttagagtac caacaccaac agtttcactt gttgatttag tgtgcgaact taaagaaaac
    11701 gttacatctg agcaagttaa ctctgtgtta aaagatgctg ctgaaggaga attaaaaggt
    11761 gttttaggat attgtgacaa gccacttgtt tctatagatt ataaaggaga ttcaagatca
    11821 tctattatag acgctctatc cacaatggtt atagaagaca atatggttaa ggtagtttct
    11881 tggtatgata atgaatgggg atattcttca agaactgttg acttagtaaa atatgtagct
    11941 gaaaaattaa aataatatat atttcttaaa gcaaatttta aaaaaatttt ttaaaaaaaa
    12001 tatataaaac taaaaaaaaa gattatgaaa aatattgaag gaaaaatttt ttcataatct
    12061 tttttctttc atgcaaaaag atacaagtta caacttatat ttgcatatta ggtcgttaga
    12121 gaagtatata tatatttagt aaggaatcat actttttata aaatgaaaga taagatgtcg
    12181 aaaacttgca taaatctgaa aaatttttat tattaaaata ctgatttcca ttttaaaaat
    12241 gataaaaaaa tgacaaataa agttgcaaat agtaatactt ataagtataa ttaaaaaaga
    12301 gaaaaggttt tgttaaactt tataacaaaa aaagaaggga tgattcaaaa tggagaagtt
    12361 aacagacagg agacaggtta aggcagtaag catggaaacc ttcattttcc taatattact
    12421 agtagttggt tttgggtatg ttggtagtat tatgggagca ggaatgatgt tcaaagtaat
    12481 aatgagtaca gcacatgctt tactattgga gacagttttc ttaattatgg ctatggcagt
    12541 tcttgcaggc gcattaagcg cactactttc agagtttgga gtaatagcgt taattaataa
    12601 aattttcgct gtatttatga agcctttata tggactacct ggtgctagta tagcaggagc
    12661 tataacaact tatttatcag ataatccagc tattatacct tttgctaaag ataaaacatt
    12721 cacacagtat tttaaacaat accaagttcc agcattatgt aacttaggaa cagcctttgg
    12781 tatgggactt atcttaacaa catttatgat ttctcaaggt acagaatatg tacttccagc
    12841 attaattggt aatttaggtg caattatagg tagtgtcata agtgttagaa taatgttgac
    12901 atttactaag aagttttata aatacaatcc ggaagaagat aaagcaacag gaacattaga
    12961 gaaaaaggat gaatttagag aaatcagaga aggaaatgta tttcaaagag ctttagatgc
    13021 aattcttgaa ggtggtaaaa tgggggtaga tatgggaatg gctataattc ctggagtcct
    13081 agtagtatgt acattggtga tgttattaac ttttggacca tctacagacc ctgttacagg
    13141 tcaagaagtt tatacaggag ctgcatatga aggaataaaa ttacttccag ttattggaga
    13201 taaacttgga tttatattag aaccattatt tggatttaca tcaccagagg caatagcatt
    13261 ccctataact tcattgggag ctgttggtgc agcaatgtct ctagttccag agtttataaa
    13321 gtcaggagct ataactccta atgatatagc agtatttaca gctatgggta tgtgttggag
    13381 tggatattta agtacacata ttggtatgat ggatgcatta aatgctagac agttggcagg
    13441 taaagctatt ctttctcata caataggtgg tttatgtgca ggagcagctg ctcactttat
    13501 atttacactc gtaggataaa tgtaatcagc taagataaaa aataatatac aaaaaaatgg
    13561 ttgttgatat gtaataagaa tttacatatc aacaaccatt tttttctgac taaagataat
    13621 ttataataca taaacattaa gtggatatta gagttaagtt atatttatgt aaaaagtaac
    13681 aaaaatctgt agaaatttat gacaaaattt agtacactaa ctatatgttc ttatttaaaa
    13741 tttaaggtta gaattaggaa ttacctagta gagtaagctt tgattaataa aagaatcata
    13801 aaataaaaat attagtcata aagattataa ataacttact taaaataaag ccatagaact
    13861 tacaaaaatt aaaaaagcat ataaatatgg aggggtacaa tggatgaatt atttcatata
    13921 ggaattgatg taggttctac aacggtgaag gttgtggtac ttaataatag taataatata
    13981 gttcataaag aatatagaag acattattct gatgtaaaaa aatcagttaa agaagtacta
    14041 aatggtatat atgaaaaatt gggagatata aatactacca ttataataac tggttcaggt
    14101 ggaattggaa tatcaaaaaa attaggtgta aaatttgttc aggaagttat atctagtaca
    14161 aaatcaatag agtattttca tcctgagact gatgttgtca tagaacttgg gggtgaagat
    14221 gcaaagataa catatctaag tggaggaata gaccaaagaa tgaatggaat atgtgcaggt
    14281 ggcactggag cattcataga ccagatggca tcacttttaa agacagatgc cagtggatta
    14341 aatgaacttg ctaaagggta taatgttata tatcccatag cttcaagatg tggtgttttt
    14401 gctaaaacag atattcaacc tcttataaat gatggagcca atcagactga tatagcaatg
    14461 agtattttca atgcagttgt cgtacaaact gtgagtgtcc tttcttgtgg aagaaaaata
    14521 gaaggaaatg ttgcgttttt gggtggtcca ttgtactttt tatctgaact tagagaagca
    14581 tttaaaagag tattggattt aaaagatgaa aacataatct tcccagaaaa tgcacaactt
    14641 tatattgcta ttggcgcagg attattatca gtagatgaag ataatataca actaaaatct
    14701 ctaatagaaa aattggatag cataaagaat attgaagatg gagaagtaaa tttattagaa
    14761 cctttattta aagataaaaa tgagtatgaa gaattttcaa gaagacatga aaaagaaaaa
    14821 ataaattatg tggacataaa ttcaataaaa agtaattgtt atttaggaat tgatgcaggc
    14881 tcaactacaa ctaaagcagc acttattgat gaggatggaa gacttgtata ttcttattat
    14941 aatagcaatg aaggaaatcc attaaaaaca accattaaag ttataaatga agtatatgat
    15001 atattaccaa aaaatattaa aatattgagt tcaactgtaa ctggatatgg agaaggtctt
    15061 attaaaaaag ctcttaaaat cgataacgga gagatagaga ctatagcaca ttacaaagct
    15121 gctaaatttt tcaataaaga tgtagatttt atacttgata ttggtggtca agatatgaag
    15181 tgcctaaaaa taaaagatgg agtaattgat aatataatat taaatgaggc ttgttcatca
    15241 ggttgtggct catttttaga gacatttgca agttctttat ctatgacaat agaagaattt
    15301 gcacacgaag gtatttattc tcaaaatcct gtagatttag gttcaagatg tactgtattt
    15361 atgaattcta gagtaaaaca agctcaaaaa gaaggtgcaa gtgttggaga tatatcagca
    15421 gggctatctt attcagtaat aaaaaatgct ttatttaaag taataaagat tagagattta
    15481 aatgagattg gtaataatat tgttgtacaa ggtggaacct tttataatga tttggtgctt
    15541 agaagctttg aaaaactaat tggaaaaaat gtaattagac ctaatatttc aggaattatg
    15601 ggagcttttg gttcagcact tatagctaaa gaaaaatatg aaagtggata caaaacatcc
    15661 ttgttatcta aggaagagtt gaataatatc aagctagaag caagtgtaac tagatgtaaa
    15721 ggttgttcaa atcattgtct tcttacaata aataaatttt ctgataatga aatttttatt
    15781 tcaggtaata gatgtgagaa gggtgaagct atttatggtg ataaaaaaat aggattagaa
    15841 aagaaaaaac caataaattt atttaagtac aaatacaata gaatttttag atataaacca
    15901 ttggaaaaag aagaagcaaa aaatggggaa atagggatac caagagtatt aaatatgtat
    15961 gaagattatc cattttggtt tacttttttc aatgctatgg gctttagagt tgtactttca
    16021 gataggtcat caaaacagtt atatgaaact ggtataacta gtattgcatc tgaaacagtt
    16081 tgttatccag gaaaattagt tcatggacat atagaaaatt taattgcaaa aggtataaaa
    16141 aatatatttt atccaagtgt aacaaatgaa aataaagagg attcaaatgc agataattat
    16201 tataattgtc ctgttgtaat atcatattct gaagtaataa aaaacaatgt agaaaatata
    16261 agaaataaga acataaatta tataaatcca tttataagtc taaatgataa ggaaaaattg
    16321 aagaaaagac tatatgatga attatcaaga catttttctg atataaaaat aactaaagaa
    16381 gaagttaatc atgcagttga taaagctact gaggaacaga atttatttaa aatggagata
    16441 caagcagcag gtgaaagagc acttaaagaa ataaaagaaa gaaatatgaa ggggattgtg
    16501 ttatgtggaa gaccatatca tatagaccca gaaataaatc atggaatgcc agagcttata
    16561 aattcattag atatggcagt gcttactgaa gactctatat gtcatttagc caatgtacaa
    16621 agaccactta gagttgtaga ccaatgggta tatcattcaa gattgtataa agcagctagt
    16681 tttgtgagag ataaaaacta tttggaactt gttcaactta attcatttgg ctgtggatta
    16741 gatgcagtaa ctacagacca ggttcaagaa atacttaatg aaaaatcgaa gatatatact
    16801 attataaaga ttgacgaagg caacaattta ggagcagcta agataaggat gaggtcctta
    16861 aaagcagcta tgtttgagag agaaagcaaa aatatagatg taaaaaatat aaaggtaaac
    16921 aggatacagt atgctaaaaa taatcagata acgaacaaac atactatatt agcaccacaa
    16981 atgtctccaa tacatttcca attccttgaa aaagctgtta acttaagtgg ttataatata
    17041 gaaattctaa aagatactga tagtagtgta attgaagaag ggttaagata tgtaaataat
    17101 gatgcatgtt atccagctat aatagttgta ggtcagctaa taacagcatt aaaatctggc
    17161 aaatatgatt taaataacac ttctgttact ataactcaga ctggtggagg ttgtagagct
    17221 acaaattata ttggattctt aagaaaggct atatatgatg ctggatttaa agatgttcct
    17281 gtcattgcac ttagtgtaaa tggaatagaa gatagtggta taatggataa tatatcacta
    17341 aaattaatca atagactctt tatgtctgtt gtttatggtg atttgctgat gaaagtacta
    17401 tatagagtaa gaccatatga aaaagttact ggaagtgcaa atgctctata tgaaaaatgg
    17461 gttgatatat gcaaatcttc tcttgttaaa gcaaaaattt ctgtatttac tagaaatata
    17521 aaagatatag taaaagaatt tgataattta gagatactag atatcaaaaa accaaaagta
    17581 ggtttggttg gagaaatatt ggtgaaattc catccaattg caaataataa tttagtagat
    17641 atattagagc gagaaggtgc tgaagcagtc gtgccagacc ttacaaattt cttcttaagt
    17701 tgtgccttta atactatata caaacacact catttagaag gaagtagaaa gagtagaatg
    17761 ataggagagg catttatata cataactgga atatatcaaa gagtatataa aaaagcactt
    17821 gataagagtg agagatttta tgctccagcc aatataaaaa atgttgctaa aagtacagaa
    17881 ccagtagtgt cattaggtaa tcaaactgga gaaggttggc ttttaacagg tgaaatggtt
    17941 gaattattaa atgaaggtgt agaaaacatt atttgtatgc aaccttttgg atgtttacct
    18001 aatcacataa ttggtaaggg ttctataaaa gaattaaaga ggttgtataa aaatgcaaat
    18061 ataataccta ttgattatga cccttctgca agtgaggtaa atcaacttaa caggataaaa
    18121 cttatgcttt ctaaggcttt taaaaatata taagatttat attttgatat gttaaaagtt
    18181 aatgaattta aaaatatact ctatattaag tatctataaa aaagagttat cctatttttt
    18241 agggtaactc tttattagtt aaaaaattat atgtatactg atattaaagg ggggaagtaa
    18301 tatgagttta gtatatgatg tttataaatc aaaattagga aatttgtaca tattaagtga
    18361 agatggtttt atagttagta tatacatagg agatgaaaaa tttaataatt taaaaaatga
    18421 atgtattaaa aaaggaattg atataaagag aagtaaggaa gatttaaagg aagcaataag
    18481 ccagatagat gattacttta atggaaaaag aaaagtcttt aatttaaata ttcgtattga
    18541 agggactgaa tttcaaaaat cagtttatag ggaaatgtta aaaatacctt atggagaaac
    18601 attgtgttat tcagatatag caagaaatat aaacaatcca aaatcagtaa gagcaatagg
    18661 acaagcaagt aaaagtaata aaattccaat aataatacct tgtcatagag tagttggcaa
    18721 aaaagatatt ggtggatata tggggaatca ttctgatttg aaagagatac tattaaattt
    18781 agaaagacag agttaactta gaaagaaatg tttttattgt taatatttga tataataata
    18841 gtaaaaagaa gtatttttta caaaaataat aaggaattta ttttaattta caaaaatgag
    18901 gggggatttt aatgtgtgat aaagttatag catcaaaata tcatgagaag ggatttaatt
    18961 gtgcagaatc agttataaaa gcatataatg aggaatttaa tacagatata ccagtttgtt
    19021 taggaagtgg actgggttca gggtgtgggg ttgctagttt atgtggtgca gtaaatgcat
    19081 caaatataat aattggatat gtaaaaggca gaaaccacga agatgaaagt actaaagcta
    19141 aagtatatgc taaagattta actacaacag taagaaaaga gtatggttca gagttatgta
    19201 tagacctaaa aaaagattta gttgcttgta gagaaataat ggatttcgca tatgatagtc
    19261 taaaggaaac tttaaaaaaa gaattataag aaaataagct atcaaatata aattatttga
    19321 tagcttattt ttatagccga tactaaataa atcaaatata ttttagaatt attatttgta
    19381 aataaacagc aaataatttt aggcttttta tttaatatag tttttattta tatttatttt
    19441 tgaatatgtt atactttgtt taaataaata tttgtaatga gggagatgag aagattgaag
    19501 aatctcaatt tacttattaa taaattatat tcaaaaaatc ataatgaagc atataaaact
    19561 tttttattct tagaaaatga aagtttaaaa tcaaatatta catattgttt ttttgactca
    19621 ttcctagaaa tgattgataa cgaaaactca tatattcgaa caaggggatt gttattaatc
    19681 tctgcaaatg ctcagtggga tattgataat aaaattgaaa taaatataga tagtatacta
    19741 agtcatatcg tagataaaaa accttctgta tcaagaatgt ttattaaatc catacctaat
    19801 attacaaagt ataaagaaaa tcttattaat cgcataaaaa tggaattaag taatgcagat
    19861 ataagtattt ataataataa tatgaaacca ttagtagaaa aggatataaa cgatacatta
    19921 tctaatatta gttaaatatt aatatagaaa ttgaatatta tctagttaca attatttata
    19981 actaagataa taaaacaaca atggtgctaa tttatatgta taaattaatt atgaaaaatt
    20041 tatataagta aaatatatta acataaaggt aaaattttgt atactaaaag ggaatattta
    20101 cagtttaatg gcagttttaa aataataaat taaagctgtc atttttattt aaaaattttt
    20161 agaaaaagta caatagtgtt aatgtgtgaa ttagataagg tgtatataat agtttagatg
    20221 atatgatata aaatatgttg taaattaaat gttttctttg acaatatata cacaaggatg
    20281 ataatatcta tatgaataaa agatagtgtg taatttgata atatgtaatt ataacattat
    20341 gatataatta caataaagta tgtaataatc tgtagaaatt tcaagctagt tatctaagtc
    20401 ggataactaa atctaaacgg aatacataat gtattaaata aatgatgata ctaaaatgat
    20461 actattttta tagaaattta ttgaggtata taattaatga aaataatata ttaaattata
    20521 taaattaaat tatataatat attgagtttt acataaaagc aaaggtggga ataaaaatga
    20581 aagaaattgc tgatgctata acatcagagt atttaagcta tggtatcaat gaagatatta
    20641 gtatctatga aggtagattt tgcatatatt tagataaaaa atatagatgt aatgggaaaa
    20701 tttattataa aatgacacct ccaatatcta taagttttaa agcagacata ggttgtgttg
    20761 aagagataga caatgaagat gacaatttag ctttagatta tgataatgct attcttgaag
    20821 ttcatggata taaaattatt tctataacaa taaatacttt aagtgaattt agtgtagaag
    20881 gttatatcaa tgatgactgc ataaaatcta agaactccta tgttgaatat gtagatttta
    20941 atataataaa cttagataaa atacctggaa aactcattaa atacaatgat aaggtatacg
    21001 caggtagaat tgaatttgat ataaatgatt atgttgtaac tatagacaag cgatatgatt
    21061 atagaaaaga attaaaatca gaattaaagt ctaaatctgg agcaataata actcatatag
    21121 gtaggattag aagaaaagat ggtagaattt ttagaacaaa taatacaata aatcttttag
    21181 ataggatatc aacagctttg agttttatgt gtggaagata tgtagggttt tgtttggcca
    21241 aagggtatag aagtggtaat gaagtttata gaatatggaa tgaaaatcaa atatctcctt
    21301 ttagatatgt accaacatgg tcagatacac tttcaaatta tcataatatg gaaaaatata
    21361 taagccttat gtgtaaaaag ctagaagatt tttattatgg ttctgctata aagagtgttg
    21421 ttgattggta catagaatct cttggaagtg ctaccatgga aaacaatata atatctgtac
    21481 aaattgcact tgaaactttg tcatatgtaa ttctagtgga acaaaataag atacttacag
    21541 atgaagtatt tgactgtaat ttggcatcta aaaatataag actcttactt gatacatgta
    21601 agataccata tggtaaacat gaattaaata tatttgataa tataataaaa aataaatttg
    21661 atgatggagt ggatttagtt atttatttaa gaaatagcat agttcatcca agtagaaaga
    21721 ctcatagagc tgtgttagag gttgaagata tttggaatat aatttcaata ggaacgagat
    21781 atattgaact tgttttactc tttattttag gttatagagg agaatattca aacagattag
    21841 tagaaagatg ttatggtgaa gtggaagttg taccttggaa ctagattttt atatttattt
    21901 taaaatatat attgacatat attgccttat gctataaaat caatatcata ataataattc
    21961 agaataacat taaatgctaa gaaaagaaat agtaaaagta gttaatctta aacagagagt
    22021 ttccgattgg tgagaggagc aatagatttt actttgaaca catctttgag caggactctg
    22081 aaagagtaga aatactttat taggagattt ccggaatcct tgcacccgtt atagtgctag
    22141 agtataataa ttttattgta cttaaagagg ttagtgtcgt gaggcattaa tgaacagagg
    22201 tggaaccacg agagttaact cccgtcctct agcagaagct agaggcggga gttttttaat
    22261 ataatttttt aagcgcgcag agaattatat tgcaatagat acacttttta aaaaataatc
    22321 aaaatatttt aaaaattaaa agacgaggga gaatattatg aaaaatatat taaaaaaagt
    22381 aggaatattt acaattatgt taggtttatt aggtggagtt gtaggttgtt caaaaccaaa
    22441 taatgaaaaa gataaggatg cttcaaagga atctaaaaaa gaagtagttg tagggtttga
    22501 taatacgttt gtaccaatgg gatttttaga tgaaaaggga gatacagtag gatttgacgt
    22561 agacttagct aaagaaacat ttaaaagact tggaatggaa gttaagtttc agcctataga
    22621 ttggtcaatg aaggaaactg aattaaatga ttcaaaaact gtagatgtat tatggaatgg
    22681 atattctata acagacgaaa gaaagaaaat agtatcatat acagaaccat atttacaaaa
    22741 taaacagata atagttactc taagtgactc aaaaataaat tcaaaagctg atttaaaaga
    22801 taaagaagtt ggaacacaac aaggttcaac agcacttgat gcagtggaaa aggataaaga
    22861 ttttatgaat agtttaaaag gtggagcacc agttctttat gatacttatg ataaagcact
    22921 tagagattta gagataggta gaactagtgc agttgttggt gatgaagttt taattagata
    22981 ctatatggga caaaagggtg aagacaaata caaggtatta aaagacgatt ttggattaga
    23041 agattatgtt gtagcaactt ctaaagaaaa tccagaactt tgtgagaaaa taaatgaaac
    23101 attaaaagaa atgaaaaaag atggaacttt tgacaaaatt tatgataagt ggtttaaata
    23161 gaagataagt tagcagttaa gaagggggca ctaaaggcat gttacaaggt ttagagatag
    23221 ttatagcaat gttttgtata acattgatag tatcaattcc attggggatt ggagttgcat
    23281 ttttaagatt atcaaagaat aaattagtaa gtggtattac acaatgttat atattgataa
    23341 tgagaggtac acctttactt ttgcaaatga tagtcatatt ttacggatta cctcttttag
    23401 gaattgtatt tgacagattt acagctggag tagtagcttt cttcttaaat tatgcagcat
    23461 attttgcaga aatatttaga ggtggaatac agtcaatcga tagaggacaa tatgaagctt
    23521 caaaagtact aggatttgat aagtttacta tgtataagag agtaatcttt ccacaagttt
    23581 ttaaaagaat actagcacct atttcaaatg aagtaatcac attagtaaaa gatacatctt
    23641 tagtatatat attaggatta aatgatattt taagaatatc tcaaatagca atgaacaggg
    23701 aagcaagtct gttaccatta tttgaggcag gagcgatata tcttatattt gtagctatac
    23761 ttactaaggg atttgaatta cttgaaaaaa aatattctta ttatagataa agttacaata
    23821 ttataggagg aggtttttta tatgttgaaa atcaaaaact taaataaatc atttaaaaaa
    23881 aatagagtac ttaaagatat ttcttttgag ttagaagaag gtcagattgg agttttactt
    23941 ggtaagtctg gtgcaggaaa gaccacaata ttaaggtgta taaatggtct tgaagaattt
    24001 gatagtggag agattataat agataatgag gtaataaaaa ataagagaga tatggcaaaa
    24061 atacgaggaa aaataggtat ggtttttcaa aatttcaact tatttcctca tatgacagtc
    24121 cttgaaaata taattgaatc cccagttaat gtttttaaag ttcctagaaa agaggctgaa
    24181 gagagggcta gagaactttt aagattagtt gatttagaag ataaattaaa ttcttatcca
    24241 tttgaattgt caggaggaca gcaacagaga gttgctatag ctaggtcatg tgcattgatg
    24301 ccaaaagtcc tttgttttga tgaacctact tctgcacttg atattgatac tattcaaaga
    24361 gtagtcaata taatgaacag acttaaagac aaaggtatga caatattaat aattacacat
    24421 gatgttgtct tctcaaataa tgttgcagat aaaattataa gtataaaaga tggtatagta
    24481 gaaaatgttc aaataaaaga aaaaattgtt tagagtttta taaatataaa ctagggtaga
    24541 attttataat ataaataaag ggcaagtaaa atcaaatata ctatgccctt ttgttatctc
    24601 aaaatttaat cttatatttt atgtttaagt tacattataa tttataataa aaataaaagg
    24661 actatttaaa tatataatgt gaataaatgt ttaataattt gaaatatgat aattttttat
    24721 gttgaaagct tataatgatt atgatataaa ttggttatag tatacaattt atgggtataa
    24781 cagtaaaaaa ttagaaagga atttttataa aatgattaaa ttatatggat atacaaaatg
    24841 ctctactgtt aaaaaagcta aaaattggct taaggaaaat aatttagaat ttgaagatat
    24901 agatatggtt caaaatcctc ctagtaaaga ggagttaaaa tcaatttata agactagtgg
    24961 atatgatata aagaaatttt ttaatacaag tggtatgaaa tatagagaat tgggtcttaa
    25021 agatattgta aaaactgaat ctgatgataa acttttagaa atattggtaa gtgatggtat
    25081 gcttattaaa agaccattac ttttggatgg taaaaatgta ttattgggct ttaaagaaga
    25141 tgtatggaaa agtactttgc taaaagaaga ttagaaagag ataggtgtgt tgattaaaat
    25201 tattaattaa tacacctata aatttatgta ttaaatctaa tttttataaa tattaattag
    25261 caaattcaaa tcaaaaaaat tcatatcagc aaacatatta cttcttatta caaattatat
    25321 catatgtttt atattaaaat attataatat tacaacgaat tgttacaaaa ttacttatta
    25381 ttaaccatga acatttgttt tgtgctatca tatttatata aggtaattat cataaaaaat
    25441 atcttgttca tacagtttta tatagaaaaa agaaatgaag cttttcttta tataagtata
    25501 ttttgtaaat tgcctctata tttatagttt aaataatagt ggtattaaaa atctgacaac
    25561 aaaaataaaa ctttcaaaaa attaaatcta aaaagaatag gagataaata tgagtattga
    25621 agatttatat gattttgaat gtgttccttt gaacaatgag attgatattg atgttttatt
    25681 tgaaaagatg atagaagatg gaaaagaaaa agaatataca ccaattatag tcattgatga
    25741 aaaagtaggg ctattaagaa aaaatataga tatgattact aaagagtatg gttctcttga
    25801 aaactataga gagtattgtt taacaaaata taatgaaatt gatgtaaatc aattttttga
    25861 ttttaggaag agtgagattt cagaattatt aaaggagcta attgatttag aagatgattt
    25921 ttatgattat aaacatttta gaccaattat gaatatagat atatttcatg aatataacaa
    25981 agtttacata gctaaaattc caacaattaa accatatgaa gtatttgcat acatacctat
    26041 tggcggattt aatgattgtc ctagagatga agaacatata gctattgcaa aatattggta
    26101 tgaaaagcat ggaatctttc caatcgcaat tggatgtgat acagttcaat attctgtaaa
    26161 aaatttaact aaagatggta aaaaatttga tgacttatgt attgaattag tattttattg
    26221 tgaggatatt attatacaag ggtatgaaac cttaaaggct cttaaggatg tattaaaacg
    26281 ctctacaata gtgctttttt ggtgggattg atattctatc atttagatag tattaaattg
    26341 ttagtcacca agaatccact tgctttagtt atggggagtg tgtcaaacta ggtttttata
    26401 cacagtgtag catagtaata tgtttaaatt acaaaggtta aaaaaatact ttaatatttt
    26461 taatattata attaatagat ttaaaggtaa ttataattta taaaataaat actttatatg
    26521 ttataatcat taagaatgta aaaaaataat atatagtttt atagttcata tttttccaga
    26581 tatggaggta aattttgtga aggaaaaaga aaaattagat aaattaaaaa aaatgttact
    26641 tgaattaggc agtgttgtag ttgcttattc tggtggagta gatagtaatt ttttgcttaa
    26701 ggttgcaaaa gatacattag gtgaaaatgt tatagctgtg actattcatg caatgatgca
    26761 ttcaagtagg gaaattgaag aggctaaaca atatactcaa aattttggtg ttaaacatat
    26821 catattaaat atagaaaact ttgatttaaa agaatttaaa gaaaatggtg ttgatagatg
    26881 ttatcattgt aaaaaatata tattctctaa aataaaagag gtagcaaaag aacataatat
    26941 aaagtacata gtagatggaa caaatataga tgatttagga gactatagac ctgggcttaa
    27001 ggcattgagt gaattaggag taattagtcc attaaaagat agtagtttaa aaaaagaaga
    27061 aattaggtcg ctttcaaaaa cattaggatt aaatactttt aataaaccat catttgcatg
    27121 tcttgcgagt aggatacctt atggagttga aataacagat gaaaatttaa gaatagtaga
    27181 aaagagtgaa gaatatctat ccaatttagg tttttctcaa tttagagtga gaatgcatgg
    27241 agatatagct agaatagaag ttggacagga agaactaggt aaattttttg aaaataacaa
    27301 ttttaataaa gttgatacta aattaaaaat atttggcttt aaatatgtta cactagatat
    27361 gtcaggatat aaaatgggaa gtatgaattt aaatgtgtag attattttaa aaataaataa
    27421 gttttatagt taatataagg aaacaggagg ttttatgaaa aattatacgt taatatcgcc
    27481 atgttttttt ggaatggaaa aaatgctggc tagagagatt actaatttag gatatgaaat
    27541 aataaaaaca gaagatggaa gaataacata taaaactgat gagtttggaa tagcaaagtc
    27601 aaacatgtgg ttgagatgtg ctgaaagagt acatcttaaa attgctgaat ttgaggcaaa
    27661 aagctttgat gaattatttg aaaatacaaa aagaataaac tggtctagat atatacctta
    27721 tggagctcaa tttcctatat caaaagcttc ctctataaaa tcaaaattat acagtacacc
    27781 agatgtacaa gccatagtaa aaaaggctat agtagaaagc ttaaagaaaa gttatttgga
    27841 ggatggtttg cttaaagaag ataaggagaa ataccctatt tttgtattta tacacaaaga
    27901 caaagtaacc atttctatag atacaacagg agatgctttg cataagagag gatatagaga
    27961 aaaggcaaat aaagctccaa taagagagac tttagctgct gggcttattt atttaactcc
    28021 ctggaaagca ggtagagttt tagtagaccc tatgtgtggt tctggtacta tattgattga
    28081 agctgctatg attggtataa atatggcacc tggcttaaat agagagttta tatcagaaaa
    28141 gtggagaact cttgataaga aaatatggtg ggatgtaaga aaagatgctt ttaataagat
    28201 agataatgaa tctaaattta agatttatgg atatgatata gatgaagaat ctatagatat
    28261 agctagagaa aatgctgaaa tagcaggtgt agatgaatat atagagttta atgtaggaga
    28321 tgcaactcaa tttaaaagtg aagatgagtt tggatttata atcactaatc ctccttacgg
    28381 agaaagatta gaagataaag acagtgttaa acagttgtat aaggagcttg gttatgcatt
    28441 tagaaaatta aaaaattggt cgtattattt gataacttct tatgaagact ttgaatatga
    28501 gtttgggcaa aaagcagata aaaaaagaaa attgtataat ggtatgttaa aaactaactt
    28561 tttccaatat ccgggtccta agcctcctag aaataataaa taagttttac atgatttatt
    28621 tgtaaaatat aaaattttat taaaataagt aaaacattat gatgccttga aacgtctaat
    28681 tattgtgagg agatttttgt gaacaaattt aaagatttaa agatttatag gattaggagg
    28741 agttaaatga aagtgttaaa gcttattact gtagtagccc tgatgatgtt atttgttact
    28801 ggatgtaata taaaaactga atctccagaa caattagcga agatacctga ctatgatgat
    28861 acaaaaaaag tattgtatga tggtattgac cagttactaa aaccagattc atctatgata
    28921 ttgccttcta atacaaaaga agtaggaaaa ataaataagg tagatttaaa cagcgatgga
    28981 attgatgaat tagtagtatt tgaacaaaaa gaagatttaa gtaataatgt gagtcaggta
    29041 gggtttgtaa ccttgagtta caatggagaa aaatacgtac ttggagacca ttttttagaa
    29101 aatggcgaat caatagaata tgctaatttt tatgatttgg actcagatgg atataaggaa
    29161 gttatcttat tggttaaatc caaagacaaa acgaatatgc atatatataa agtagtagat
    29221 aatgaaataa caaaaatata tgacttggat gcatcatggc ttcaaaataa agaagatttt
    29281 aatgacatga aagtaaaaat tggatatata gatggagatg acaagttaga catattgatg
    29341 cttcatttga ataataagac taatgaaatg tttgcaagtg ttgcaaattt tgatgggaaa
    29401 atgaaaatca aagattctgt taagtttgaa aatgtaaaaa acttaagtga attatatata
    29461 acattaggta atgttgcttc atctgttgga aattcttctg cagctataaa aggtattgta
    29521 cttgatattc ctatattgaa agataataac tatattacgc agatacttta tatgaaagat
    29581 gggaaaatta acaaagcttt tagtgattat gataaaacta ttactaaatc ttattatata
    29641 cctgtagatg atattgacaa agataagatt atagaaatac ctatagttgc aggcagtaca
    29701 ggtaataata aaaatactta tagttctaaa tcatctgcaa ctataagttg gtatagatgg
    29761 aatggaaaag aaggtgctga ctcaagttta atatttacaa gtcagatata ttataattat
    29821 aaatataatt ttaaattatt tattccaaat aatttatttg ataaaatact tgttgaacag
    29881 gaatttgttg gagaaaaagc agtatttaaa ttttactatt ttgactattc agaccgtaag
    29941 aatttattta atatagtagt agagagtaaa aataaacttg aagatagaaa aaatacaggt
    30001 actcaaaatt ctattgtact tcaagagagc gatgaatata ctttcttact agttgtaaac
    30061 aatgcaaatg aaatggataa gctagatatg actatagacg cattaaaaga atatttctca
    30121 ttaatatatg gttaatatta tactcaattg gaggttttat tttatgaagg aaaagatact
    30181 tatactagaa gatgaaattg gtattagaag ttttgttagt ataaacttaa aaagggaagg
    30241 ctatgaaata gttgaggcag gtactggaag agaagctata gaaaaaatga caacagaaaa
    30301 ggatattaca atagctcttt tagatgtaat gcttccagat ataagtggta tagaagtatg
    30361 taaatttata agggagaatt ttgaccaagt aggtataata atgcttactg ctaaagctca
    30421 agaagatgat aaaatagaag gatttatctc aggagcagat gattacatca taaaaccatt
    30481 tagtataaaa gagcttttag tcagagtttc tgctcttctt agaagagtag caaaggatga
    30541 ttcaagtgtt aagtcgagtg agatagtttc tccaccattt atacttgata tagacaaaag
    30601 aaaattattt aaaaatggaa aggaaattga gcttacacca actgaatttt caatagtgaa
    30661 atatctaata tcaaatgcta agcagtcgtt aagtagagac cagatattag acgaagtatg
    30721 gggaactaac tatttatatg attttaaaat agtagatgta aatataagaa ggataagaaa
    30781 taaaatagaa gatgacccat caaaaccaaa atatatacaa actatttggg gttatggata
    30841 ctgttttaga aaggaagaat aatagtgtta cattttgaag gtctgagaaa aaaagtaata
    30901 aaaaactatt ttataataat tattataatg gttactctgt ttgaaggatt gttcatgttt
    30961 tacatacaaa actactatta tgattctgtc aaacagctac ttgaatctga aataaaatat
    31021 gctgatgaat ataatgctat tacaatggaa actacaagtt ttgagaaaaa agtaaaaaat
    31081 atatttgata aacaaccctt aactaaaaat tcagaatttg gaatttcaat aatagataaa
    31141 gataaaaata ttatattaga ccaatatggt tttaaaagta aagaaaaagc aaactatgaa
    31201 gatgttaaca atgcattaaa agatataaaa actaaaaatt taacacctta tacttataga
    31261 ataccagata caggagagca tgttatgagt atctccttac cacttaaggt aaataatata
    31321 atagaaggtg ttgttagata tacagtatca ttagatgcta ttgataatgc aatattaaag
    31381 caagctacat ggcttatatt agcaggaata tttatactta ttatagctat actaataagt
    31441 cttaaatttg ctgagactct tataaaacca ttacgagagc taaagaaatt tgcaaatgaa
    31501 ttggctgtag gaaattataa tataaaatta gaaaagatga agattgtaga tgatgaaatt
    31561 ggtgatttag cacagacatt tgaacacatg gcacatgaga ttgacaaaag tgaaaaatta
    31621 aaagaggaat ttatatcatc tgtatctcat gaactaagga ctcctcttac atctataaag
    31681 gggtggagtg aaaccttagg ttatgaaagt ataacaagag aagaactaga cttaggttta
    31741 ggcattatac aagatgaaac agaaagactt ataaaactag ttgaagaatt attagacttt
    31801 tcaaggcttt cttcagacag gataaaactt catgttgata tagttgatgt tgaaggttta
    31861 attgtaggtg ttgtaaatca acttaaagtt aaagcagctg aaaaagatat atcactttta
    31921 tttgaatttg aaaatgaatt tatagagaac attcaaggag ataaaaatag attaagacag
    31981 gttctcataa atttaataca aaattcattt aaatttacga gtcaaggtgg ttacataaaa
    32041 gttgtagctt ctcaagatga agagataaca accatatcag tagaggataa tggttcaggt
    32101 atagaaaagc aaaatttaaa taaagtgtta gataaatttt tccaagaaga ttataataag
    32161 gctggtagtg gattaggact agcaattagt aatgaaattg taaaacttca tggtggaaga
    32221 atgaaaatag aaagtgaaaa gaatgttgga acaaaaataa cttttaatat aaaaaataaa
    32281 tttgctaaac aagcataaat tcttagaaag aggattaaga tgagaaacat aaaaatgata
    32341 gtagcatacg atggttcaag atataaagga tatcaaaaat taggtgacaa taatatgact
    32401 attcaagaaa aacttgaaaa tgttttaagt aaaatgacta atgaaacagt ggagataata
    32461 ggttctggaa gaactgatat gggagctcat gcaagaggac aagtggtaaa ttttagaact
    32521 aattgtatgg attctttgga taaaattcaa aaatatttat atgaatattt accagaagat
    32581 atagttgtaa aaactgttga agaagttgat gaaagatttc attcaagata caatgtaaag
    32641 tcaaagactt atatgtataa aattgacaat aataagtatc ataatccttt tataagaaaa
    32701 tatgctactc atgtaagtaa aaaattagat ttagatagaa tgagaaaagc aagtgagtat
    32761 ttagtaggag aacatgattt tactagtttt gcttcttcta aatctaagaa aaaatcaaat
    32821 gtaagagaaa tttattctat aaatataaaa gaagatgata atgttataga aatatatgta
    32881 gaaggaaatg gatttttgta taacatggta aggataatag taggtgcttt gatagatgtt
    32941 ggtctaaaaa gaagagctcc acaagatatt aagtatatgc ttgaatcaaa agatagatgt
    33001 caatcatcag atactgcacc agctaaagga ctatgtcttt ggaaagtaac atattaatca
    33061 attatataaa actctcttta aaataaaaat aaaataaatt atatagttga cataaatgga
    33121 aaaataaact attatatatt ttataagaga gatataaaac tttatattta aatcctgtga
    33181 gaaagagagt aacttctatg tgttttatag agagctgagg atggtggaag cttggcaaat
    33241 aagtattagt gaaaagaact ttggaggata ctaattgaat ttagtatgtt agtaggtaat
    33301 ctcgccttaa gagaaagagt ggataagttt atcttatcaa ttagagtggt aacgcggata
    33361 tatttcgtct cttggttttt ccaagaggcg ttttttaata tatttaatta ttagtgttta
    33421 tctggtatgt tgaacattta ctaattgatt agctaagttt atcaataaga gtggtaccgc
    33481 ggatatttcg cctcttagta ttttaaaata ctaaggggtt tttttagtat taaaatgatt
    33541 ttatgtgagt ctaaattctc agagtcattc aatattaaga atttctataa aataaaaatt
    33601 ataatttaag attgggagga attaaaaatg aaggaaaaag tagtattagc atattcagga
    33661 ggacttgaca catcaatcat aataccttgg ttaaaggaaa attatgaaga tatagatgtt
    33721 atagctgttt gtggaaatgt aggtcaggaa gataaaatgg aagatgtata tgaaaaagct
    33781 ttacaaagtg gagcatcaaa ggcatatgtg gatgatataa gtgaagaatt tgtaactgaa
    33841 actatattta aagccgtaaa agcagaggct aaatatgaag gaaaatactt attaggaact
    33901 tctttagcaa gacctataat agctaaaaaa ttagttgaag ttgctcataa agaaggtgca
    33961 aaatatatat gccatggatg tacaggaaaa ggtaatgacc aagttagatt tgaagctaca
    34021 attgcagctc ttgacccgac tataaaagtt attgcacctt ggagaatttg gaatataaaa
    34081 tcaagagaag atgctataga ctatgctgaa aaacataata taaaggtaac agcaactaaa
    34141 gctaaaatat attcagtaga tgctaacctt tggcatgttt caacagaagg tggagatata
    34201 gagcacctag aaaatgaaca taaaaaagat gtttataaac aatgtgtaga cccagaagat
    34261 gcatgtgatg tagctgaata tgtagaagtt tactttgaaa aaggtgtacc taaaaaggta
    34321 aatggcgaag aattatctcc agttgcactg attcataagt taaatgagtt gggttgtaaa
    34381 catggaattg gtgttataga tatagttgag aatagacttg ttggtatgaa atcaagaggt
    34441 atatatgaga ctccaggagg aacaatcctt tatgaagcac ataatatttt agaaagtgct
    34501 actttagaca aagatacatt acatttcaaa caaatggtat cttataaata cggagaactt
    34561 atttacaatg gactatggta ttgtaaatta agagaatcta tagatgcatt tatggaacaa
    34621 actcaagata atgttacagg aacagtaaaa gttaaacttt acaaaggaaa tataaaacct
    34681 gctggaatat ttactgaaaa tgctctttat gatgaaggaa tatcttcttt tggaaatagt
    34741 gaactttatg accacaaaga tgcagaagga tttattaatt tattcacttt accattaaaa
    34801 atcagagcta tgaaagctgg aaaataataa aataaattat ttaagagtgt ataaaaacta
    34861 tttttaggtt tttatatgct ctttttttat ttgaatttat taaattatac agtaaatagt
    34921 ataaaaaaat atattatagt tccaaatggc ttaataatgt gaaaatataa gacctaaaat
    34981 ataaatttta taaatacaat agttattgac tctctcattg taagagggtt tatactgaat
    35041 ctaatgaaaa tttatagtga ggagatagat tatatgagaa aaataattga aattaaacat
    35101 cattcacatg attatgagtg tatgtggaat ggtatagaag atttatatat aaataaaacc
    35161 ggtgaatgcc ttccaaacga ttttttcttt ttactgtcag gttttggttc attttgttat
    35221 atgaaaacaa ataaagctga tttgaaaaga atggtagctt tgggagatgg aaggacaaaa
    35281 cagatgtata aatttttagc accaattgtt ggatttgaat acaaacatca tgagtttaaa
    35341 aagtatgagc aagcattaaa gaaagcaaaa tctgaaattg atgatggata tccagttatt
    35401 ttaggagctt tagatatgta ttatctacca tattataaga agctatatca taaagaacac
    35461 attccttttc attatatatt aatggtagga tatgatgatg aaggaatata tctgtatgat
    35521 tgtggtagaa cagaattatt acatctttct tatgataaat tacgtgaaag catgaattga
    35581 aattcccctg gattaagcaa agaaaatact atttgcacaa taagaatgaa tacttcaaag
    35641 aataaatata acattgctag agaagctatt gctataaagc gtgatatgtt tttaaatcca
    35701 cctaaaggat ttttgggata taaaggtttt gaaaagttta ttaaagagtt gccacagtgg
    35761 aacactgaat tggataaaga tgattatgat aagattttga ccaatatggt tatgtttttt
    35821 ggaacagtac caacaattcc aaatgcaatc aaaggaatta aagaaccaga tactgttcaa
    35881 tttaaaggtg gatttgataa aatgagtaga atgctcaaca gtattgggga ggaatacaaa
    35941 aacgactctt ttatacaagt agctgatatt tttgataaaa ctgctattat aattgagaaa
    36001 atatccaata ttataataga ttacttaact caaacatgtg atgatacagg acaacttccg
    36061 ttattgttct ctgaggtctt agagcatatg aaaacaggat atttaatctt ggatgtataa
    36121 aaaatatatt gttgacccta acattacgta atagtgtaat atgaaaatat agcttgaata
    36181 tattagtagg tattgatggc tgtaaaatta aaatttgagg tgtggatatg agaacagtga
    36241 aacaagtttc tgatttaact ggaataagtg tgagggcatt acattattat gatgaaatag
    36301 gtcttttaaa accaaataaa attacagatg caggatatag actttatgat gatgaatcta
    36361 ttaaaactct tcaacaaatt ttatttttta aggagattga tattccttta agagaggtta
    36421 aggaaataat gtcaagccaa tattttgata aggttgaagc tctaaaaaat caaaaaaaat
    36481 tacttatttt aaaacgaaag agactggatg aattgataga gcttataaat caaactctaa
    36541 gaggagaagg aaatattgat tttaaagagt ttgatatgag cgagtatttt gatgttttag
    36601 aagaatttaa aagagagcat aggaataagg taattaaaat ttatggtagt gtagaaaaat
    36661 acaatgaata tatagaaaga gttaagtcta atgaagagaa aattgctaaa atggctataa
    36721 aacaatatgg aactattgag aagtttgccc aagctataaa aacaaatttt agcagtgata
    36781 tattgaattt aggagaaaaa tttgatagat ataaaaatga ttgtttaaaa gaaaaacatc
    36841 caaaattaaa agaattatat agaaagcttg tagaagattt aagtaggaat cattcttcaa
    36901 cagaccttca agaaatagca aaagagataa cagatatatc taaaaaagat tatgaaattt
    36961 tctctatgga tactggtgat gacaactggt attatatggt tcaaaattat ctagtaaatc
    37021 ctatgtggat agaagaagta gataaaaagt atggaagtgg agcaggtaag tttattggac
    37081 aagtactaaa gacttatcta agagatagaa aaccaaagat aaatacattg tatgaaaaac
    37141 ttgtagaaga tttgagtaga gattgttctt caagggaagt tcaaagcatt gttgaagaaa
    37201 tagacaatga aatgaaaaga agtaatgaat tttataaaat agacaatggt gaaagatact
    37261 ttgattatat gtcagagctt tatttacaag attctaacta tataaaagta actgataaga
    37321 attatggtga tggtgcatct aagtttattg gagaagcttt taagatttat tttgataata
    37381 ataattgttg aaaatttgga agtaaaaaat atgtaagttt tataaaagca caaaaataag
    37441 gatgtagatt agctccatct atatccttat ttaaagttat taaaatatat agtttacatc
    37501 aaacttaaca ctttcaataa tatttcccaa atatgttttt atactttcaa cttcttctaa
    37561 agattttaat ttattttcag tataaattgc tttgtccaga atattaaacc ttaatcctat
    37621 ttcatcaaag tactcatgat ttaaaacttt gtaccaatgg tttttttctt tattccaact
    37681 cgtagatatt gaatcagctt ctttttgagc tttttcccaa tcttcatttt ctatagattt
    37741 ttctaaaaca gatatattgt ctttatatcc ttctgtaaaa tcatatagtt tattgttaac
    37801 gtaaaatcca aataatacaa ataagatagt ccatagtata acaaatgttg tagatttcaa
    37861 tattaatcac cctttttatt ttgaataaat attttgtcat tttcatctaa aacacaaata
    37921 agaacatctt taaaagtttc tatgtgatta gattttaaaa tacccattaa ccagttagta
    37981 tctttttgag ctatgtctag atttttattt attattctac catccagtat aagtgggata
    38041 ggtaaatgat taaaagctct tggaggagta ctattgtagc ttgatgctgg tacaacactt
    38101 agattaccat cagtctccaa aatagcatat tgtacatctt ttaggttaaa gtatccttga
    38161 atcctaagtt gttctaataa ttcatctata ctaattcttt cttttttaag ctctttatat
    38221 acaatttttc ctttatctat taatacagaa ggtttacctg ataaaaatga acttaatttt
    38281 ctgcttttta atgataagaa tgaaattaga gtctgcatga ttacaagtcc agatattgct
    38341 gcaacaccat ttatgattgg tatattatta ttttccattg ggacagatgc aacttctgca
    38401 attaatagtg ttataactaa atcaaaacag ttcatttcag ctatttcacc ttttcccatg
    38461 actctaagtg caattagcac tgttatgtat aatataatac ttcttattaa tactactgtc
    38521 atatctatca attactcctt taaaaaatat ttacacttag ttagtatatc ctatataaaa
    38581 aatttaattc aaagtataaa aaaccttaaa taattggatt caactattta aggttttttt
    38641 gataatttta atattaaatt ttttatggat tttctgttac ttttatttat tttaataaca
    38701 gattcaacaa aactcttttt atctcctaat tttaagataa aatcaggata ttcttcaaat
    38761 tcattgagtt ttattaattt gaaagaagaa gatagatttt taaagttaat aattttagag
    38821 ttattcacta atacacttct ttttttaaaa taaatttctt ttttacttat atttagtata
    38881 gttaatattt gtttaagata tattattata tcttctggag ttctatcaaa tttgagttca
    38941 aaattttcat cttcaaagta gggaatataa tataaaggtg ttttgagagc aggtaattta
    39001 ttatataatt cttcaagaat atcgatattt ttaggggagt taaagaaaaa gcatttacac
    39061 acattcatta aatccacagc atctgaaagt gagttatgtt taatatctcc ttctacagaa
    39121 aaaatttttt tcatattcag taaagatatt tgcttagata agattctatt attgtatgta
    39181 atatgttgag atataaaagg ttgaatgtca atcatcatat taaataactc taagcattta
    39241 cctgtatatt tatatactct aaatgaagtt agaaggccag ttatatcaaa atcaccccaa
    39301 ttatatattg taacatcatc aaatttacaa aaccatttat aaaaatcatc cataacatat
    39361 aaaagattag gagcattatt gatatctagt tggttcaatt tggttaaatt tttacattta
    39421 tttgaaagta ttttattgta ttttggctta actaaagagt aataattatc tattgtatta
    39481 aattcgttat caactaaaac tccaccaata gaaattaatt ccgcaccatt atattctttt
    39541 ggtttatttt tattatcatc tagtatatta aattcaaagt ctataaataa cttgtatttc
    39601 ataaatctaa agcacatcct caggtaaatt atttattgag cctaagcatc ataagaatca
    39661 atagatataa tgactctaaa catcaaaggt tcattacaac ttttatttat ttcataattt
    39721 aattcaaata aatcttttaa gatataattt ataagtattc tttcccaacc catttttaaa
    39781 ttaactttag agtctattaa tatattttct atctttttaa atatttctat atttgctggt
    39841 attatactga gctcaatatt acttttaaac gggttagact gtaaatctgt tataagtata
    39901 ttttttaatt cctctgtaag ttcagaaatt aaactatcac ctatgtattt ttttatgatt
    39961 tcctctctaa tttcttttaa atttagcaat attagtacct gctacttaca tagtagcttt
    40021 tcctttcctt ttaatactat tattcatttt tgaatcttat ttagatatat tttaagatta
    40081 aaagtcttta gctatataat tttttaccca tttttaactt atattaacat attacaggct
    40141 tatatctcca ccctgcttac attgaggatg gagtatattg cctattttga taaaaatgat
    40201 aggttgttat ttgcctattc ctttttctga taatttttct aacatatctt tggtcatttt
    40261 atctaaatca taactaaact taaagttcca ttcttttact gcactactac tgtctagaga
    40321 gttaggccaa gaatcagcta tactttgtct tacagggtct acatcatatt ctatcacaaa
    40381 atcaggaata tattttttta tagaatcagc tatttcttca ggagaaaagc tcatagcagt
    40441 aatattaaaa gcatttctat ggatgagttt atcagctgga gcttcgatta aatccactat
    40501 tgattgaagt gcatcaggca tatacatcat atccattttt gtaccttctg ctatataaga
    40561 tttatatctc ttatttttta atgcctcata atatatatca actgcataat ctgtagttcc
    40621 tccaccagga ggcgtaacat aagaaataag acctggaaat ctaacacctc tagtgtctac
    40681 tccaaatttt gagtgataat aatcacatag taattctcca gaaactttag tcacaccata
    40741 catagtatta ggtctttgta atgtatcttg aggagtcata ttttttggag aattttcacc
    40801 aaaagcagca attgaactag gtgtaaaaaa tttacaatcc aattctttgg ctatttcaag
    40861 accatttatt aatccattca tatttaagtt ccaagcttct agaggtttac tttcagcaac
    40921 tgcagaaagt aaagatgcta gatgaattat agtatctaca tcatattttt ttgcaatttc
    40981 aaaaaaacga ttcttatctg taacatctaa tatctcaaat ataccagatt cacatactgg
    41041 attaccttct tttactctcc ttgaactagc gattacattt tgttctccat actcatttct
    41101 aagctttatt gttaattctg aacctatttg tcctaatgca cctgttataa gtattttttt
    41161 caatttcaca acctcctaag ggtttaattt atgtagtact acttattttt attttagcaa
    41221 atcttttgtt taaatacaaa gaattaaaga taataatata cgacttaatt gaatgaagtg
    41281 cagtaagtgc ctaaaaattt aaagctaata tataatggtc tattgtataa caataaaaga
    41341 gtagattaaa ttattatata tagattgtgt gactaagtca cagaaaatag agttaattta
    41401 atatataata aaagcatatc aagtaaagct ttaaattaaa gtaactttat ataaaaagta
    41461 atataaattg ataaaattat aaatttattt atagtgaata taggttggat tttatagata
    41521 caaaaatagt atatatgata tgtagaccat tagcatgttt aaagtagcaa aacatataaa
    41581 ataaaatttg aaaggaagta taaaaatgac aagaccatca atatatcata gccaaggata
    41641 cacttgtgca gaggcattaa taaagtctta taatgaggaa cacaacacag atataccaat
    41701 ctcaatagga agtggtatgg gggttggaat gaatgttgga agtgtttgtg gagctgtaaa
    41761 tgctgctgtt gttataatag ggtatttaaa tgggcgaaat agtaatttag atgaaaatat
    41821 agcaaggaag tattcaagag agctattgaa tagagtaaga aataaataca gctcagaaat
    41881 atgtgtatct cttaaaaaaa ataaagtaac ttgtgaagaa ataataaatt tcacatatga
    41941 tgctctaaat gatatgctaa aaaatcaaaa ataattctaa gaaacaagta ttttacattc
    42001 gatagaatac ttgttttttt atgatatttt taataagtat tagtttatta taatttttaa
    42061 atcaatttta ttatatttta attgaaacaa tctactttga aaattactaa ctgacaaaag
    42121 aatatgatta tagtatagaa aaaatgtaaa ttatttaata ttaagtgaga gtatatgttt
    42181 acctatataa aatcgtataa attaatggct aaatttataa attataaaga aatatatagg
    42241 aaaacaaaag aattaattag tataatataa agttaaaaag ttaaaattta tataatttat
    42301 ttataaagta aagaaaaaat agaaatttgt aataaaataa aaagtttatg acataatatg
    42361 gtataattag taaaaatata gagattggag gaattgcttt gtttatagat gaagaattag
    42421 aaggttatat attaacatgt aaaatatctg aagactttaa aaatatacct gaatatagtg
    42481 atgaagagtt ttatgttaca gtctataaag atgaaagttc tgactctggg tactatgctt
    42541 tattagaaaa taaagaagaa agagttgtat gggatggaga agttgttgcc aataatattt
    42601 ttaataacct ttggattgta gtaaataagg ttaaaactgg ataatagtct aattatatag
    42661 tatttgtaat attttaaatg aatttttaca tatttgagat gagtaaataa caaagattat
    42721 tcgatactgg aggagtaatt caatggaata tagttatagt aagatgaact taaaaaaagg
    42781 ggatattgta gaggtaaatt tagagaaaca agccaatgta atattgttag accatataaa
    42841 ttatgtgaaa tttaaaaatc aaagaaatta tgattactat ggtggatttg caaagaaaaa
    42901 tccatgtaga atgagagttc ctaatactgg aacatggtat ctagtagtaa atcaagatgg
    42961 aaatagtgga atagtaaact tttcaatcaa tacaattcaa aattaatttt agaatattgg
    43021 atattcttac tttttgtact ttttatatag ttaaaataaa attaataagc aattattata
    43081 aaataatgtg ggtgcctcaa aatgaatttt ataattcacg agacactctt ttttatatga
    43141 actcaaatat actttatcat ttcaacaatg aaaaagaggc gtatctgtgt tttgagatag
    43201 cctcatttat catatatcat atatagaatt ttaattattc ttaactaaaa ttttttccat
    43261 aggttatctg tacaattaaa atatttattg ttagcataca gctccacctg taaggtgtaa
    43321 aagagcctct agtatctctt cttttctttc caaaacttca tctgataaaa gcatttctat
    43381 aaatttatca gcaccgattc tatcgatagt tattccaaaa cgttcacctg tgttaccctg
    43441 ttctctaaat aaaagaattg ctttttcaat taaagtcata agttcctctt ttgaaaataa
    43501 tctatcaatc tgtgttccag gacgaactga ttttccccat ttccctccta tatagacttt
    43561 ataaccagat tctttttctt caatactatc aaaattacaa ctttctatac acttaccaca
    43621 gttattacat agattactat ctatttcaag tttaccttta tctgttaatt tagctgcttt
    43681 aacaggacag acctctacaa cagcacattt tttacaacca acacaaagct ctgaatcata
    43741 gtcaggtaca cgttgaccaa caattccaag atcatttagg tcaggtttaa tacagttatt
    43801 agggcatcca ccaacaccaa ttttgaactt atgaggtagt tttacatcat accaattttt
    43861 gtaaaattct tcgtgtattt cagcagcaag tgcctgtgta tcagctagac catgaacaca
    43921 aacagtacct ttacaagcca caacaggacg aacccttgat ccagttccac ctgttattag
    43981 attttcgcta gcaataaatt cacttagagc ttcaatatct tcaaatttta caccaggtaa
    44041 ttctactgtt agtctagtag taaatgctaa ctgaccgttt ccgaattttt cagcagcttc
    44101 tgcaattttt tttgcttgtg atgcatttat tacaccattt acagttatta tacgtgctgc
    44161 aaaatgttct ccatccctgc ttggtagaaa acctctacct tttacttcct ttttttgttc
    44221 tgctgtaaca ttactcatat ttactcctcc attaccttaa gatttggata aaatagtgtt
    44281 ccaccttcaa gaactttcgt atttgtatag ccaaagcgtc ttaagcgatt ttgcgccata
    44341 tagctatttt tacctttagc acatataaga agaatttttt catccttagc aaggccttca
    44401 atttctccat taatttcacc aacaggaata taacgtaaac taggaataga aggagctttt
    44461 gaaacatcaa gtttagtcca actgtcaaaa tcctcaattt cgtcaagtaa aacactatca
    44521 agttctccat taagtttatt ttgtaaaaca tttactgcca ctacaaaagg gtgaatagct
    44581 gttgaaaaag gtggtgcata tgcaaggtcc atactttcta atgaataaag gtcagcgcct
    44641 aaagttattg cagtagcagc gatatctact attttatcaa ccgctccagg tcccataact
    44701 tgaacaccta ataattttct agtatttttt tcagcaacca ttcttataat aaaattagat
    44761 gcacctggat aataatgagc tttatcatca gtagctatgg ttacagagca aacattataa
    44821 ccttcttttt cagctatttc tttacttaga cctgtttttc ctgcattgag ctcaggtaat
    44881 tttactactg ttgttccaag aacaccattg taagttttag attttccaga tatattttgt
    44941 gcgcaaattc taccctcatg atttgcagat gaccccatag gtgaccatgt aggtttattt
    45001 gttaaagaat tttttacaaa agcacagtct ccaactacgt atatatcttt gtcatttgta
    45061 agcatatatt catctgcaat aattgtatta ttaggggcaa attctaaacc tgtgtctttt
    45121 agaaaacctg tgttaggacg gattccaact gacataacca ctaaatctgt tttaatagct
    45181 ctatttttag tacgaagttt ttcaacttta ttttcacctt caatacctac aacctggtca
    45241 cctgtaaaaa tcattatgcc tttatcagcc atatgatttt caacgtattc agcaaaatca
    45301 gtatcaaatc caggcataac atgttcagcc atatcaacaa cacttacacg tatacccatt
    45361 gcagaaagat tttcagcaat ttcaagacca atgaaacctc caccaataac aacagctctc
    45421 ttaataccgt tttcaataga atctcttagt tttatagcat catttggagt acgcataaag
    45481 aatactccag gtaaatctat tccaggtatt ggtggtttta ttgggtctgc ccctgtagca
    45541 attacaagtt tgtcatagct tagattttct ttttctcctg ttgaaagcgt tttcaaagtt
    45601 acttgttttg catttctatc aatagatgta acttcaactc cacaacgaac ttctgctcct
    45661 gttagtttag aaaaactttc aggtgtattt acgattaaag atgatttatc ttcaattatc
    45721 ttaccaacgt aatatggaag accacaacct gcataagaaa tatcatcacc tttatttagt
    45781 attgtaacag agcaattatc acccatttca cgttttattt ttgcagcagt ttttgttcca
    45841 gcagcaactc cacctataat taatactttc acaatatatc acactccaat ctactttata
    45901 actctataat aaaattatac ttcttgacaa tatatttgta aaatactaaa atattaataa
    45961 aatcataagc atttactaat gtttgctaag gttgtgataa tatgacaatt cgtagtcttg
    46021 aaatctttgt taaggttgct gaatgtggta aaatgagtga agtagcaaga aatatgtata
    46081 ttacccagtc atcagttagc caagctattt cagaaataga aaaagagtat ggtgttaagc
    46141 tatttgatag aatttcaaaa aaattatatt taactgaggc agggaaaaaa cttcttggat
    46201 atgggaggca tcttttagct gtaaatgaag aaatgaatga ttgtatgaag cattgtgcaa
    46261 aaaatatccg tataagagtt ggggcaacag taactgttgg tacatgtgta ataagtccaa
    46321 taatgttaga attatacaag gtaaatcctc ttatagaacc tgaagtattt gtagaagata
    46381 caagactgat tgcaaaaaaa ttacttaata gtgaattaga tattgcgatt gtagaaggaa
    46441 aaattaagca cccagatatt gttacaaaaa gcattattaa tgataatctt gtacttatat
    46501 gttcacacaa gcatgagttc tacaaaagag actctataaa agtttcagaa ctttcaaatc
    46561 aaccattaat tatgcgtgaa ttaggaagtg gtacaagagc acaattagaa aagcaattaa
    46621 aagaattaaa aatcccaatg aatattagat ggtcatgtta taactctgaa gctatattaa
    46681 gagcagttgt agataatttt ggcattgcag ttatatccga attacttatt gaggattatt
    46741 taaaaaagca tcttttgtgg gcttgtgata ttgaaggtat taatttacat aggacatttg
    46801 atattgcata tcatagaagc aagtttttta cagaaaatat ttcagcattt tttgatattt
    46861 cagtagaata tgggaaaaaa caagcgagaa agaagagtag aagtgtaaac agtttataat
    46921 atatctaaat aaaaataaga gtatataaat atactcttat ttttatttag atatattagc
    46981 ctatattaac gccaaaattt ttacacaatc ctgcaagtcc atcctcaaat ccagaaccta
    47041 aagcattaaa tttccactct ccattatgtc tatatagttc tgccacaact attgctgttt
    47101 ctatgctaaa atcttcaccc aattcatatt taataagttc ctcattagtt tcttcattat
    47161 atattcttat atatgaattt tcaacttgtc cgaaattttg tcttcttgta attgcttcgt
    47221 ttatagtaac actaaatgat attttagcaa tattttgagg tattttagat aagtctacat
    47281 ttatttgttc atcatcacca tcaccaacac ctgttctatt atcacccata tattcaacag
    47341 ctccagaagc gtgttttaaa ttattataga atataaagtc tccatcattc gttacttttc
    47401 catcagttcc agttaaaaat gcagaggcat ctaaatcgaa atcaaagcca ccatcatatt
    47461 tattaatatc ccatcctagt cctactatta ctttttttag accagggtta ctttttgtta
    47521 aacttacttt ttgtcctttt gctaaagtta tacccattta aaccaactcc tcattataaa
    47581 ttttttattg taattattac ttatatgtat taattaattc acgaagctct tcattttgac
    47641 caattcctaa agcattaaat ttccattctt catttctacg ataaatttct cctgccaaaa
    47701 ctgttacttt accagaaaag tcttcttgaa gattatattt aaataattct tgcttggaat
    47761 ttgaatcaat taatcttata aaagagttgt tcatttgacc aaaatcctgg tctctttttt
    47821 tagctttgta tatagaaact ccaaaaacta ttttatgtac atattcaggt atgtcttcta
    47881 aattaacaat tatttgttca tcatcacctt caccttttcc agttaagtta tctccagtgt
    47941 gtataatagc tttagaaggg tgtttaagat ttccaaaata aaccaagtca cctctaacat
    48001 tcattttatc ttggttagtc aatgctattg caaatgcatc taggtcataa ttttttttac
    48061 ccaatttatt catatcccat cctaagccta ctactagatt ttttacagga ttattatctt
    48121 ttactaagct aactctttgt cctttttgta aactaacact cattttaagt tctccttttt
    48181 atatttttag ttttattgat ggtatcaagt ataagaacca tattagctat attatatacg
    48241 tatttaggct aagttggcta tatttataaa ttatttatta tataactaca tgaatatttt
    48301 ataatttaaa catattgaca ttatatgctt taaattattt tgtagtttta taatatttaa
    48361 atttgtattt gattgttata aagtaaagta agtaataaag ttagactcaa taattctaaa
    48421 atttctaagc atactatcta aatgagaacg gatttggaaa tacttgtata aaacaataat
    48481 tgatacattt aatttttatc ttaaaaacaa caattataat atataaatag caagtataat
    48541 ataacatata aaaagttgaa tttgtatatg ttaattatac ttgctattta tttgttagtt
    48601 attctatttt tttaaatcca ttacctaaag cttcatgtat atctgtaatt ataataaaag
    48661 cattagggtc gacatttttt actaattttt tcaattcgac aacttctttc ttttcaacta
    48721 ctactaaaag tacattttta ttttctccag tatatgcacc ttctcctttt agaatagttg
    48781 cacctctatc taaatcttcc attatttttt tacttatatc ttttgaaagg tcagatataa
    48841 tagtgaatga tttggaataa ttaaatcctt caataagcaa gtcactaact tttactaaaa
    48901 tgtataaagc cacagttgaa taaagtgcaa tttcaacctg tctatttact atacctgata
    48961 aaacaactac aacgcagtct acaataccca ttaaaacagg tatactaaat gtaggaaaat
    49021 atttatttag taggagtgcc attaaatcag ttccacctgt agagccattt attctaaaaa
    49081 taagtccttg accaactccc attaaaatag aaccagatat aattgcaaga tacatatcat
    49141 ttgttatatc taatgtagcc atatttgcag taagcttaag tgctatggta agaaaaatta
    49201 ttcctaaaac cgttttaaaa caatcttttt ttgaaagtat tttgtaagca aatatgaata
    49261 atggaacatt taaaagtaaa ttgacaatcc aaagttctac accgaataat gaatttaaaa
    49321 caactccaag tcctgttata ccaccagcag cgattgcatg tggattaaaa aataagttaa
    49381 gagaaatggc cattaatata cagcctacaa ttaatattaa aatttctgaa aaagttattc
    49441 tatctttttt caataacatc actccttata tatagattat aatatatatt atatagtttt
    49501 tccaattttt aataaaagaa ataaaaatat attataaaaa caatttgatt ggaattttca
    49561 gaaaattaat gctataatta aaagtaaatt taaagggagg ttataaaatg gctaaattaa
    49621 ctctagaaca tataaaagga aatacatatt atattccact ccctacaata gtaggtgtat
    49681 acgtagatgg taaagatgca attttaattg acagtggaaa taataaggat acagctagac
    49741 aagttttaag attattagaa gaacataatt taattcctaa attaataata aacactcatt
    49801 caaatgcaga ccatatagga ggaaatgcat atttgaagaa tcaaacaaaa tgcaagattg
    49861 ctacgactaa aattgaagga tattttacag aaaatccaat attagaatca gcatttttat
    49921 atggtggcta tccaagtaaa gcactgaaga ataaattttt attagcaaag gaaagtgaag
    49981 ttgattatat tatacctcca aatggcaaaa ttgtagatac agaacttgaa gcgatttctc
    50041 ttccaggtca ttattttgaa atgattggtg ttagaactcc agataatgtt ttgtttgttg
    50101 cagatagtct tacaccagag aatataatta ctaaatatca ttttttcttc ctactggata
    50161 tagattcaca gtttaagaca ctagaaaaat tgagaatgtt agaggctgat ttctttgttc
    50221 caagtcactc tgtcaaaact acagatataa aaagtttgat taatattaat aagaagaaga
    50281 tggaagaaat aatagataat attaaaaagg tttgttatga gccagttatg attgatgaag
    50341 ttattgaaaa aatgtgtgat ttgtacaatg tcaagcttga tgctaatcaa tatgtgttgg
    50401 ttggaagtac aatacgttct tatataactt atttatatga gaataatatg gttgaatata
    50461 tatttgatgg tggtaagatg atgataaaag ctgtgtaaat agtaataatt ttcaaattat
    50521 atgatgaaat tgttttagta tgactgttat ttgaaaagta atataaaaaa atttatataa
    50581 ataagctaag atgattgata taaagttact gataatttta aggtaatata tacgttacta
    50641 taatattatg ttattatttg taaataaggg gataatttat aagcaaatta aagaccttaa
    50701 tttacaggag gaatagtgta tattatgaat aaaaaattca aaaaattcag taaaaaacta
    50761 agtatattaa ttttagtttt gactatgttt ctttttaata atttaactgc aaatgcacag
    50821 attaaagaag attcaataat aggaattgat agatatgaaa cagcaggact tatagcagat
    50881 agacaaactt atgatactgt aatattagtt aatggagata aaaatttatc tgatgggctt
    50941 tcatcaagtg gattagctgg agctattaac gcaccaatac ttttgactaa aaaaagtgaa
    51001 ataccaaaag ctactttaaa tagactagat aataagagtt taaatgttgt aaaaaaagta
    51061 tatataattg gtggttataa tactattgaa aattcagtag aaaaagatat aaaaagaaaa
    51121 ggtattcaag tggaaagaat aaatggtaac aatagaattg aaactagtta taatgtagct
    51181 aaaaaaataa atgaagtaag tagtgtaaaa gaggtaatgc ttacaaatgg atttgtagga
    51241 gaggctgatg ctatgagtat agcacctgta gttgcaaaaa ataaaggagc tataatactt
    51301 acagatggga aatcagttcc atttaagact gaaggtttaa atgtttacgc tataggtggc
    51361 aaatctgcga taaatgagga tttagtaaat gaaactaaag caattagaat cggaggaaat
    51421 gatagatttg agaccaataa aaaggtaatg gaaaagtttt ataatggagc tacagatttt
    51481 tatataacaa atggatatca attagtagat gcactaacat tatctccttt agccaaagaa
    51541 aaaccaatcg ttttagttgc tgatggaagt aataaaggta ttttaaaagg agctaaaagt
    51601 ataacaaaag ttggaggtat tgatgccaat atatataaac agtgtttaga tatgattaaa
    51661 tataataata tggatatgac tccaaatatt ttaaaacact taacttcagt tgaaggaaat
    51721 gaagtttctg aaatacttat agaatcagat aatttaggtg tggttgttga aaagacgaat
    51781 accaataaat ttgagtttga ttacgtaagt gtaactaatg aaaaaaattg tactttttct
    51841 gtatataaag aaaattcttc taataatata aaaaatggaa agctagttgt aagtgctaag
    51901 aaaaaaatag ataagaaaga tagtgatttg caagatatga atggcgacaa tatgataaat
    51961 gcaaataaag ataggatggt aaatgtgata aaaattggag ttcccgataa aatgtattct
    52021 aattttaaag tagatgttga aagtggttca gtagaacttt ataatattaa aggaggagct
    52081 actgttgatg tcaatgacgg gattgctaac attgttgata acaatgtaac aaatcctttc
    52141 aatataaata ctaatagtgg gatttcaggt gtaacagctg aaactatatc atctgaaata
    52201 aaatttagag caaacaatgg aattgtaaat gtaacagcta cgaatataaa tggcaatata
    52261 agtttatttg gaagcgataa taaaggtacc tttgatggaa tatttaaatt aaatctgaaa
    52321 aaagaaccat caaatttaca cttgaagtta attggaaatg ggataaataa attgccagaa
    52381 ggttggtcta aaaattatat tttaggaaat ggacaaccaa ttattgaagt taaaaataat
    52441 ggcataaata atatatcaat tggagaataa aaacatatga aaataaagtt tatatagttt
    52501 taaaaattat agaattttaa aatatttata tatattcttt aaataaaaaa ttatttttta
    52561 agtgataatt aagtatttat caataaggct atggttgtaa aaatcatagc cttattttta
    52621 tattataaat aaattagagt attta
//
LOCUS       DAEOTL010000017        52594 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEOTL010000017 DAEOTL010000000
VERSION     DAEOTL010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 52594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.017"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            518..1513
                     /gene="ilvC"
                     /locus_tag="KRH82_001338"
     CDS             518..1513
                     /gene="ilvC"
                     /locus_tag="KRH82_001338"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBG8654627.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            1566..3254
                     /gene="ilvB"
                     /locus_tag="KRH82_001339"
     CDS             1566..3254
                     /gene="ilvB"
                     /locus_tag="KRH82_001339"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBG8654628.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVASMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            3464..4141
                     /locus_tag="KRH82_001340"
     CDS             3464..4141
                     /locus_tag="KRH82_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBG8654629.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            4315..6351
                     /locus_tag="KRH82_001341"
     CDS             4315..6351
                     /locus_tag="KRH82_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBG8654630.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDENYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGIFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(6542..7108)
                     /locus_tag="KRH82_001342"
     CDS             complement(6542..7108)
                     /locus_tag="KRH82_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8654631.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            7396..8331
                     /locus_tag="KRH82_001343"
     CDS             7396..8331
                     /locus_tag="KRH82_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654632.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINHEI
                     KKYGRRFKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGNGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            8797..10011
                     /locus_tag="KRH82_001344"
     CDS             8797..10011
                     /locus_tag="KRH82_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654633.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(10430..10951)
                     /locus_tag="KRH82_001345"
     CDS             complement(10430..10951)
                     /locus_tag="KRH82_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654634.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYNKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            11307..12104
                     /locus_tag="KRH82_001346"
     CDS             11307..12104
                     /locus_tag="KRH82_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBG8654635.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            12214..12804
                     /locus_tag="KRH82_001347"
     CDS             12214..12804
                     /locus_tag="KRH82_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBG8654636.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNKIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            12870..14567
                     /locus_tag="KRH82_001348"
     CDS             12870..14567
                     /locus_tag="KRH82_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBG8654637.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            14781..15620
                     /locus_tag="KRH82_001349"
     CDS             14781..15620
                     /locus_tag="KRH82_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBG8654638.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            16137..17993
                     /locus_tag="KRH82_001350"
     CDS             16137..17993
                     /locus_tag="KRH82_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBG8654639.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    18076..18316
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    18382..18617
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18702..19919
                     /locus_tag="KRH82_001351"
     CDS             18702..19919
                     /locus_tag="KRH82_001351"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBG8654640.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            20036..20518
                     /gene="cdeM"
                     /locus_tag="KRH82_001352"
     CDS             20036..20518
                     /gene="cdeM"
                     /locus_tag="KRH82_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBG8654641.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            20783..22048
                     /gene="hisD"
                     /locus_tag="KRH82_001353"
     CDS             20783..22048
                     /gene="hisD"
                     /locus_tag="KRH82_001353"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBG8654642.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(22251..23003)
                     /locus_tag="KRH82_001354"
     CDS             complement(22251..23003)
                     /locus_tag="KRH82_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654643.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFNY"
     gene            complement(23121..23390)
                     /locus_tag="KRH82_001355"
     CDS             complement(23121..23390)
                     /locus_tag="KRH82_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654644.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            23865..24959
                     /locus_tag="KRH82_001356"
     CDS             23865..24959
                     /locus_tag="KRH82_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBG8654645.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKREKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVES
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            24961..25911
                     /locus_tag="KRH82_001357"
     CDS             24961..25911
                     /locus_tag="KRH82_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBG8654646.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRAKHG"
     gene            25904..27088
                     /locus_tag="KRH82_001358"
     CDS             25904..27088
                     /locus_tag="KRH82_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654647.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISNYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRITKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGNVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIIAPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            27101..28597
                     /locus_tag="KRH82_001359"
     CDS             27101..28597
                     /locus_tag="KRH82_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBG8654648.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSTSIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            28620..29570
                     /locus_tag="KRH82_001360"
     CDS             28620..29570
                     /locus_tag="KRH82_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654649.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMFLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLVSFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            29591..30553
                     /locus_tag="KRH82_001361"
     CDS             29591..30553
                     /locus_tag="KRH82_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBG8654650.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIAKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            30925..31557
                     /locus_tag="KRH82_001362"
     CDS             30925..31557
                     /locus_tag="KRH82_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8654651.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            31968..32060
                     /gene="kdpF"
                     /locus_tag="KRH82_001363"
     CDS             31968..32060
                     /gene="kdpF"
                     /locus_tag="KRH82_001363"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBG8654652.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            32101..33783
                     /gene="kdpA"
                     /locus_tag="KRH82_001364"
     CDS             32101..33783
                     /gene="kdpA"
                     /locus_tag="KRH82_001364"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBG8654653.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            33808..35865
                     /gene="kdpB"
                     /locus_tag="KRH82_001365"
     CDS             33808..35865
                     /gene="kdpB"
                     /locus_tag="KRH82_001365"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBG8654654.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            35884..36510
                     /locus_tag="KRH82_001366"
     CDS             35884..36510
                     /locus_tag="KRH82_001366"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBG8654655.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            36747..37655
                     /gene="cysK"
                     /locus_tag="KRH82_001367"
     CDS             36747..37655
                     /gene="cysK"
                     /locus_tag="KRH82_001367"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBG8654656.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            37682..38272
                     /gene="cysE"
                     /locus_tag="KRH82_001368"
     CDS             37682..38272
                     /gene="cysE"
                     /locus_tag="KRH82_001368"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBG8654657.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            38432..38620
                     /locus_tag="KRH82_001369"
     CDS             38432..38620
                     /locus_tag="KRH82_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBG8654658.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(38674..39543)
                     /locus_tag="KRH82_001370"
     CDS             complement(38674..39543)
                     /locus_tag="KRH82_001370"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBG8654659.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(39740..40984)
                     /locus_tag="KRH82_001371"
     CDS             complement(39740..40984)
                     /locus_tag="KRH82_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654660.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLGEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKSRLAKINIKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            41275..41586
                     /locus_tag="KRH82_001372"
     CDS             41275..41586
                     /locus_tag="KRH82_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBG8654661.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKKIEQL
                     T"
     regulatory      41679..41771
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41871..42665
                     /gene="thiD"
                     /locus_tag="KRH82_001373"
     CDS             41871..42665
                     /gene="thiD"
                     /locus_tag="KRH82_001373"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBG8654662.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            42689..43477
                     /gene="thiM"
                     /locus_tag="KRH82_001374"
     CDS             42689..43477
                     /gene="thiM"
                     /locus_tag="KRH82_001374"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBG8654663.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVKGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            43500..44132
                     /gene="thiE"
                     /locus_tag="KRH82_001375"
     CDS             43500..44132
                     /gene="thiE"
                     /locus_tag="KRH82_001375"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBG8654664.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            44271..44573
                     /locus_tag="KRH82_001376"
     CDS             44271..44573
                     /locus_tag="KRH82_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654665.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(44639..45388)
                     /locus_tag="KRH82_001377"
     CDS             complement(44639..45388)
                     /locus_tag="KRH82_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654666.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPFILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(45382..46344)
                     /locus_tag="KRH82_001378"
     CDS             complement(45382..46344)
                     /locus_tag="KRH82_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654667.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVKMFGKDLVDNSSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(46348..46806)
                     /locus_tag="KRH82_001379"
     CDS             complement(46348..46806)
                     /locus_tag="KRH82_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBG8654668.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            47162..47518
                     /locus_tag="KRH82_001380"
     CDS             47162..47518
                     /locus_tag="KRH82_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654669.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            47590..48306
                     /locus_tag="KRH82_001381"
     CDS             47590..48306
                     /locus_tag="KRH82_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654670.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            48299..49123
                     /locus_tag="KRH82_001382"
     CDS             48299..49123
                     /locus_tag="KRH82_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654671.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            49135..50334
                     /locus_tag="KRH82_001383"
     CDS             49135..50334
                     /locus_tag="KRH82_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654672.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            50343..51155
                     /locus_tag="KRH82_001384"
     CDS             50343..51155
                     /locus_tag="KRH82_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654673.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            51166..52434
                     /locus_tag="KRH82_001385"
     CDS             51166..52434
                     /locus_tag="KRH82_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654674.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPDISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGVVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
BASE COUNT        20572 a         5487 c         9088 g        17447 t
ORIGIN      
        1 taaaatagcc gtccaataag aacggctgga aatagaaaag gaacgtcatg ttaggcgttc
       61 catagtctat aggttattca attttttctt gtttcaatac tgatgtgttg taccatatct
      121 ttgcatatct aggaaaactt gcgtatcaag gctcattcgt tagtagtaaa taagtagtaa
      181 attgatgtgt ttgtttcctt gaaaatgctg atagatactg tattttagcg gataatcaga
      241 tttttattgt gtttttaaaa taaaaaacta aagataaata ttaaataaga aaaatcttag
      301 attaaaatat aagtgtcatt gaatttatta gtttatcaca gttaataaat ttattagttt
      361 gttgtagcta ataaaaactg aaaattctaa aattataatt gtaagattat ataaatttag
      421 aatttaaatc tgttgaataa tattaaaaca atgataatga gtatgaattt ctaataaaaa
      481 taaatatcat aaaaataaga aaaagtattg ggaggaaatg aaaatggcaa gaatgtatta
      541 tgaaaaagat gtggatttag aggttttaaa aaataaaaag gttgcagttt taggttatgg
      601 aagtcaagga catgcacatg cacaaaatct tagagataac ggtgtacatg taatgatagg
      661 tctttatgac ggaagtaaat cagcacaaaa agcaaaagaa gatggatttg aagttaagag
      721 tgtagcagaa gctacaaaag aaagtgattt gacaatgatg ttaatgcctg atgaaaaaca
      781 aaagaaagtt tatgaagaga gtgtaaagga taacttaaaa gaaggtcaga cattagcttt
      841 tgctcatgga ttcaatatac attataatca agtacaacca ccagaatttg ttgatgttgt
      901 aatggtagct cctaaaggac ctggtcactt agttagaaat gtatttacaa agggaagtgg
      961 agttcctgca ctatttgcag tatatcaaga ctacactaaa aaagctacag agacagtttt
     1021 agcatatgca aaagggatag gagcaacaag agcaggtgtt ttagaaacta cttttaaaga
     1081 agaaacagaa acagatttat ttggagaaca atcagtactt tgtggtggaa taagtgaact
     1141 tataaaattg ggatataaaa cgcttgtaga tgcaggttat caaaaagaag tagcatattt
     1201 tgaatgttta catgaaatga aactaatagt cgaccttata tatgaaggtg gatttgaaag
     1261 aatgagatat agtataagtg acacagcaga atatggagat tatgtatctg gtaaaagagt
     1321 aataactgat gctgcaaaac aaggtatgca aaatgtttta gaggatatac aaaatggaaa
     1381 atttgcaaaa gcgtggatta aagaaaatga agaaggacgt gaaaacttcc taaaaactag
     1441 agaagaagaa tataatacag aaattgccga agttggtaga aatctaagaa gtatgatgtc
     1501 attcttaaaa taaatatata ttaaatggat tagtttgagg gaaagagtgg tgtatagtag
     1561 tgcgtatgaa tggagcaaag gtaattttag aatgtttaaa gaaagaggga atagacacaa
     1621 tatttggata tcctggtgga gccgtgatac ctctttatga tgctctatac gattattcag
     1681 atgattttaa acatataagg acatcccatg aacaaggttt agttcatgct gcagatgggt
     1741 acgcaagaag tactaataca gtaggagttt gttttacaac atctggtcca ggagcaacaa
     1801 atgccataac tggaatagca acagctttta tggattcttc acctatggtt gtaatttcag
     1861 ggcaggtgcc aactagttta ttaggaaaag attcttttca agaaattgac ataactggag
     1921 caacattatc tatgacaaaa cataattatt tagttagaaa cactaaagaa ttagttccta
     1981 caataaaaga agcttttaga gttgcaaatt caggtagaaa aggacctgta cttgtagatg
     2041 ttccaaaaga tttattttta gcagaaatgg attttagtgg tgaggactat gatttatgtc
     2101 aaatagatga ttatatggat tataagagtg attttgatct agatgatgaa actaatatta
     2161 agcttttaaa tgaagcaata gatatcataa aagaatctaa aaagcctgta atatatgcag
     2221 gtggaggtgt taaatcttca gacagtgagg aaattcttga aaaatttgca actaagatag
     2281 atacacccgt actaaataca cttatggggc ttggaaatat agatagaaag aatgaactat
     2341 ctcttggaat ggttggaatg catggaagta gagaaagtaa tttagcactt tctaattcag
     2401 atttagtgat agcgataggt gcgagattta gtgatagagt gataagtaaa agttctgaat
     2461 ttgctaaaaa tgcaaaaata atacacatag acatagaccc atctgaaata agtaaaaata
     2521 tagaatctaa tgtatctttg gttggagatg taaagctagt ccttagttta ttaattgaaa
     2581 gggttgaaag taagaataat agcaattgga aagaagagat aaagacattt agaaagagtg
     2641 agggtgtaca aacatatgaa tttcatccac aaaatatact taaaaaaata aatgaaaaat
     2701 atgaaacatt aaagaaaccc actgtggtag taactgatgt cggtcaacat caaatgtggg
     2761 ctgctaagta ctggaatttt aaaggtaata aaagttttat aacatcagca gggttaggaa
     2821 ctatgggatt tggtttaggt gcagctattg gaactaaagt tggtaatgta gataaaaatg
     2881 tagttttagt cactggtgat ggaagtttta gaatgaactg taatgaacta gctacagttg
     2941 caaattataa tgtacctatg cttattttac tactcaataa tagaacatta ggaatggtaa
     3001 ggcaatggca aaagttattt tccaatcaaa gatactctca aactgacatt aatgaaaatg
     3061 tggattatgt taaactcgta aatgcatata atattgatgg atataaggta gccagtatgg
     3121 aagaattagg aaaggcgcta gatatgatag attttaataa acctgtattt ttgcaatgtg
     3181 atatagataa ggattatgat gtttatccta ttgtagcacc taatgatgca ttggaaaatt
     3241 tgatatgtaa ctaaaactta tactgaatat tgataaaatt ttttattaaa tttttattgg
     3301 tattcagttt tgttgtttag agatagattg gcatttttta ttttttcaaa taaatcaatg
     3361 actatataat tgagaactta ttaaatttta attatacaat ttggaatagt attacaactt
     3421 aagtaaataa taattttgaa taataattta cggaggtatt catatgttta aacacgataa
     3481 agcattatta aaagaagtaa aagtagaaag accaaatcct caatatgctg ttttaatgca
     3541 agaacagttg ggtggtgcaa atggagagtt aaaagcagct atgcaatact tgtcccaaag
     3601 ttttagaata aaagaccctc aaataaaaga tttatttctt gatatagcag cagaagagct
     3661 tagccatatg gaaatggtag cacaaactat aaatttatta aatggacatg atgttgatta
     3721 taattcagtt aatacaggcg aaatagaaac acatgtatta actggtctat caccagtctt
     3781 aataaactca tcaggagctc cttggactgc taattacgtt acagttacag gggatttagt
     3841 agctgactta ctttcaaata tagcttctga acaaagagct aaggtagttt atgagtactt
     3901 gtatagacaa atagatgata aatatgtaaa agaaacaata gatttcttac ttaatagaga
     3961 agaagcacat aatgctctat ttagagatgc tttaaataaa gttaaagata caggttcaaa
     4021 tagagatttt ggagttacag aagattctaa attatatttc gatttgtcta ctccagggcc
     4081 aaatcacgat actaagatag atattaatcc tccttctttt gaaaaacctt taaaaaaata
     4141 atttgatatt ttttatgttg ttttgtttta gtagttataa aaattattta ctagaagaat
     4201 taattatatg aaaaattaaa tatgtatagt taaaaatggg tatacactta ttataagtgt
     4261 atatctattt gtttattgca aaacatataa taaaataaca aatgaggtgg tattttggac
     4321 agtaatagaa aacctaataa tctaataaat gaaaaatctc catatctttt acagcatgct
     4381 tataatccta taaactggta tagttggaat gatgaggctt ttaaaaaagc aaaagaagag
     4441 gataaaccaa tatttttaag tgtaggatat tcaacatgtc attggtgcca tgttatggaa
     4501 aaagaatctt ttgaagatga agaagttgct gaaataatga atagaaactt tgtggcaata
     4561 aaagtagata aagaggaaag acctgatgta gatagcgtgt atatgacagt ttgccaagct
     4621 atgacaggta gtggtggatg gccaatgacc ataataatga caccagataa aaaacctttt
     4681 tttgcgggaa catatttccc aaaatattca aggtataata gacctggagt tatagattta
     4741 ttagagaatg tatctgaaaa atggaataca agcagggata tattaataaa atctggagat
     4801 gaaataatag aagctcttaa ggatgatttt ggtgtaaaaa atactgaggg tgatttatca
     4861 aaagagatgt tgagttcatc agttagagta tttaaggcta tttatgatga aaattatggt
     4921 ggttttggta atgctcctaa atttccaagt cctcagaatc ttatgttttt aatgaaatat
     4981 tatagtatag aaaaagataa agatgtgtta aaaatggtgg aaaaaacttt agatggaatg
     5041 tatagaggag gcctgtttga tcatattgga tttgggtttt caagatactc tactgataaa
     5101 aagtggttgg ctcctcattt tgaaaaaatg ctatatgata atgctatgct tactatagct
     5161 tttttagatg cgtataaaat aacaaagaaa gagttatata aagaaattgc tataaaaact
     5221 atagattatg tagttagaga gatgaaggat aaagaaggtg ggttttattc agcacaggat
     5281 gctgatagtg aaggtgaaga aggtaaattt tatacattta atcctcttga gataattgaa
     5341 gttttgggtg aagaagatgg aattttcttt aataattatt ttgatataac tagtagtgga
     5401 aattttgaag gcaaaagtat tcctaatctt ataaaaaata aagaatatga aagacataat
     5461 gaaaagatag ctgaccttag taaaaaggta tttgaatata gaaaagaaag aacatctttg
     5521 cataaagatg acaagatact tacatcatgg aatgcattga tgatagttgc tttaacaaag
     5581 gcatatagta ctttaaaaaa tgacatatat ttagagtatt caaataagtg tcttaacttt
     5641 ataaataata atcttgtaaa tgagtcaggt agattattag ctagatatag agatggaagt
     5701 tccgactatt tagcatattt agatgattat gcttttttaa tctgggcgta tatagagctt
     5761 tatgagtcaa catttaatat gaaatattta gaaaaggctt taaatttgaa tgaaagctgt
     5821 atcaaccttt tttgggatta tgaaaaaagt ggattttata tatatggtaa agatagtgaa
     5881 aatttaatag caagaccaaa agatttgtat gatggagcta ttccatcagg aaattctgtt
     5941 caattataca atcttataag acttgcgaaa attactggag ataatagact tgaagaaatg
     6001 tcatataaac aattaaaact gtatgtggat aatgtaaaga gttctccaac tggctacagc
     6061 ttttatatgc tttcattgat gtttgaactt tattctacta aggaaattat atgtattttt
     6121 aaggaagatt ctgatttaat tgcatttaaa gaattgataa gtgaaaattt tataccaaat
     6181 gcaacttttt tagcaaagaa atacaatgaa gaaaacacta ttataggttt tttaaataac
     6241 tatatattga aggatgataa gactagttat tacgtgtgtc aaagtaatag ttgtagtcaa
     6301 ccaattaatg atttacaaaa attaaaagat atgattttag gagtagaata atcataatag
     6361 cgaaaaagga gatgctttaa aataaaagtc taatcatctc ctttttttgt acaaaaaaca
     6421 gaaaaagagt tcctaagaac acctaatcta tgtaatgatt gttttgttaa aaaataaaaa
     6481 tgacattata gttatataaa atattgtact acaaaaaagt agtattatag atgcgatagt
     6541 attaatcgtt tttatttact ctctttcttc tttttgcaaa ttcttcaagt gcttcagatt
     6601 taattttatc tatttcttca tattccataa aattagcatc ttcttcaaag ccatcttgtt
     6661 cttcaccatt aaaacgatac atttttttta gtaaactcca taaggtctct aattcatctt
     6721 tggtaaattc gtgaaataca tctgccataa agtttattcc agtcctacta catgtcacca
     6781 taaccttttt tcctaagtct gtaactttaa cattaattgc tctcttatca tgaggacttg
     6841 gaattacatc aacatatcca tttttttcaa gattagcaac tagtctattt atattttgtt
     6901 tacttgtacc catttttctt gcaatattat ttaatgttgt ttcttcctct ggtaaatgaa
     6961 gaattgataa aatagtcata tactgtcttg aagtaagtat accaaaatat ttatctcctt
     7021 ctatttgtat tttgtttgta agggtaaaaa gagttgcata tgtttgattc attaaaaaga
     7081 gctcttttag ttcatttgaa taatccatga aatatatctc ctttattttt agatgttgtt
     7141 ttgtcgaaaa cagaatatca tgaattaatt ctaatgtcaa tatggtgtca aaatatatta
     7201 aagtgttact tttttatgta actattaatt aattaaatta ttgtataatt ttatgtaaaa
     7261 acttctatgt accaatgata acttctatga ggaattaata attcttaaat tttttagaaa
     7321 gattttgact tgaaaatact tgtaatataa tatataaatt aatatactga ataaaatcaa
     7381 tctggaggga taattatgaa gtgtacaaac tttactttca aaggagagga aggtttagat
     7441 atatatacat ataaatggga agatgaaaat ataaaaaaac caaaggcagt tatccaaatt
     7501 gcacatggaa tggctgaaac tgcacaaagg tatgagactt ttgccaaggt acttactaaa
     7561 aatggttata tagtatatat caatgaccat agaggtcatg gaaaaactgc aaagataata
     7621 gaaaatgttg gacatttagc tgaaaaagaa ggatttagat gtcttgtaga ggacatgtat
     7681 actttaacaa atattataaa gaaagaaaat gaagatttgc caatttatct atttggacac
     7741 agcatgggtt catttgcaag tcaaagatat ataatggatt acagtaataa tttatctgga
     7801 cttatactat gtggttcaaa tggaaagcaa ggaatcattc taaatcttgc tcatctgata
     7861 atcaatcatg agattaaaaa gtatggaaga cgttttaaaa gtaataaaat aaataatttg
     7921 atatttggcg gcgaaataat aagaagaaat gaaaagacta agtttgactg gttaagtaga
     7981 gataaagaac aagttgaaaa atatataaat gacccatttt gtggagtagt gtgtagttgt
     8041 ggcttttttt atgatttagt tcaagggtta aaagaaattg aggataaaga aaacttaaaa
     8101 aaagtgccac ttgatatacc tatttacata atatctggag ataaagaccc cataggaaaa
     8161 aatggtaacg gagtcttaag actaagggat agatatataa aattaggagt aaaagatgta
     8221 acttgcaaac tttacaaaga tggaaggcat gaattgttga atgaaataaa tagagaagaa
     8281 gtttttgagg atataatttg ttggttaaat aataaaatag aaatattgta ataaaaaaaa
     8341 tataatgata tatttacttt aaatttattt atatataata tttgaaaagt ggattatgta
     8401 tatgcaaagt agaaaagaga gagcctagaa gtgatttttc gctacaatgc catttattga
     8461 ataggtgggt gttattataa ataaattatt aacactcagt attattatca ttgtatatgg
     8521 aatttatttt atttaaaatt ccttgaaagt ttaaatatag taagttgtag taaagagaaa
     8581 atctaaatat ttaaatgcta tttaatgtga atctattaat taggttatac ttaaacttaa
     8641 ttaatagatt ttatatttca agctaatgag atagggtttt agattaaaat ataaccaatg
     8701 gttaaattac agacattttg ttaactttcc ctcgatttac tagtaaatat ttttttaata
     8761 tacttaaatt acaacagatg tactagggag gtatatatgc aaattaaaat aggtaaagtc
     8821 atacagcgtc ttagaaaaga acgaaattta actcaagaac aattagcaaa gtttataggt
     8881 gtgtcaacac cagcagtatc taagtgggag agtggaaatt cttacccaga tatagaatta
     8941 ttgcctttat tagcagactt ttttaatgtg tctattgata agcttttaaa ttacaagatt
     9001 gatttaagtg aagaagaagt aatgaaaatt tataaagaat tagaatcagg ctttgctaga
     9061 attgaaattg atttatcaac agaagaacca aaagaagaat ttagacaaga cttagaatct
     9121 gtaaaaaagc tttccaatat gtatatagag aagtatccta aaagctattt attgaagcta
     9181 aggatatgtt cgctgtatca gatgtattca tataaatttg gtaagagtga acttaatgac
     9241 agagtaaaag aaacaacgaa tattcttgaa gatatagtga gaaatacaga tgatatccaa
     9301 ataaaagaaa cagctcttat tatattatca aacgcatatt gtatgttgga ggattatgaa
     9361 aaggcagagt tgtatttaaa tatgatacat aagtcaatag gggatacaag tgttaattta
     9421 gctatgatat atttaaagca aaatagactt gaagaagcag aaatattgct tcaaaataaa
     9481 ttgtttagta atgtatttaa tataagcatg gattgtaagg gaataattaa tgtatacaaa
     9541 aatcaataca aggaattaaa gaaaaaattg gagaatagaa attttaataa aaatgcaatt
     9601 gagagagaaa tggagtatat aaaaaataag ttgctggggt atgcaaatct ttctttagaa
     9661 ataaaaaaaa tgctcagtga agataaaggt gcatttttta gtatgtatat ggattatatg
     9721 gaattatctc taattttttt attttttaac atgaaagaag aagcaaaaaa agccttatat
     9781 agtctaaaag aaatattaga aaaatatcct atacatgaaa atttggatgt aagtcaaatg
     9841 agattttttg ataaggtaga gtctaaaaat ttatatactt ttaatatata tacaaacttg
     9901 ttaattgtac ttaatgatga tagttataat gagcttagag aagaaccaat ttttaaggat
     9961 gtaattgaaa agattttaga tatggaaaaa atgttgaaaa ataaagaata agtaaaaatt
    10021 taatatagga cttaaagatt aatcaaatta aaagaaagtg tttcaaaata aaaatttgaa
    10081 tcaccttttt tgtctgtctt aaacagttat ttagaaaaat agaggtttca aaatagaaat
    10141 ctgaattatc tgtattatta cacaaaaata gaaacctaaa tttataaaaa tagaataaag
    10201 tttgttatat aaaatgtaat tttgtctata aaatctcacc tgttttctaa ctttaagcgt
    10261 gaaaaagaga atgtatcatg aattttttag ttcatgatgc atccttcttt gtatgaaatc
    10321 caatatatct ttattattta aacaatggaa aagagtctta tttctatttt gagacatctc
    10381 ttttatttaa ttatgaagtt ttatacagtt caataaatag gaattatatt tagaaactca
    10441 tgacattatt tcttagatag tgattaaatt tatcatattc cattttagat aacttttctg
    10501 ggtaagacat tacaatcagg ttatgcccat taaatttttc atggtatggt ggatgaatgt
    10561 gttcataatt atttgtctta tattttactc tttcatagaa cgccttgcga taaattgaaa
    10621 tctcatcaat tggaaggtca atttctaaaa taatagtttt tcctttctta tttaaaagct
    10681 ctaacgctct ttgtccatat ctattattgc gcatttctgg aaaaatgcag aaatgttcta
    10741 catagataaa gtcatctgtt tcccaacata aaattatgcc gacaaactgg tttttattat
    10801 aaattaaatt gaattgatat tctttatttt tcaaaatttc ttcttgcaaa gaagattttc
    10861 tttgttcatg aaatgggaaa ctaattttat ataattccat agccttgtaa tataatttat
    10921 tttcactggt tcttaaccgt tcaaatttca ctttactcct cctaatcacg aaaattccaa
    10981 tttatttatg agttcatttt accatagtca gtatttgcat acaatgtgtt ttaagttgag
    11041 tgtcatttct ttcttttatt tatgtttata tctcatagac taagagataa ttacttaaga
    11101 cataactaaa aactattata ttaagctttg ataatctaaa aacagtatat ttatggactt
    11161 ttctaggtct aaaagtaatc ttaataattt tagaagttac aaaaaagtta cataaatttg
    11221 gaaagctata atatacatat ataatataag gttaaaactg taatgaataa tattaattta
    11281 aaatttgaac atggaaggag attattatgg agaaaagaga aaagaggata ataatatcat
    11341 ctttattaag tgtatcaatt ttaatgggtt tggtaagtat atattctata ttaaataaag
    11401 aagacataat tttaactgtt aagggtcaag agcaaaaagt atcttccttt aagaaaacag
    11461 ttgaggaact tttggatgaa cagggtgtaa agtataattc tgaagataag attaatccaa
    11521 gtttagatac agaactaaaa gatgatatga aaataaaagt tgttaaggta actaaaagta
    11581 aaaaagaaga gattgaaaaa attccatttg atacaaagca tgtaaatgat agtaatttgt
    11641 taaaaggaaa atctaaagtt tatcaagaag gtcaagaagg agaaaaaaaa ctagtctata
    11701 atttaactta ccatgatgga aagttagtca aaaaagtctt atcaaaagaa gtaatatcta
    11761 aggagccaac tacaaaaatt ataaaatatg gaactaaaga aaaagtacta atagcatcaa
    11821 gaggagcaaa tataagagga ggcaaacata tgaaagtggt tgccactgca tatgcaggag
    11881 atacaataac atctactggt acaactccaa gatggggtgt tattgcagtt gacccacgtg
    11941 taataccata tggaacaaaa gtatatatac ctaaactggg tatgactttt gtagcagaag
    12001 attgtggagg tgcaattaaa ggtaatagaa tagacatttt tatgaacagt gaaggaaaag
    12061 cttcaaattg gggaaggaaa agtatagata tatatctaca ttaaattagt gaatagaata
    12121 actttacttg aaggacaaaa aagtataaaa tatgaattaa ctaaactgtt agattattct
    12181 taaaacataa aaatatatct aaggggggat aagatgaaaa tagtctgctt aggagacagt
    12241 ttaacgtatg gatttggggt atcacgaagt aattcatgga caaacattgt aaataaagag
    12301 actcgattag aaatagtaaa taagggtata aatggtgata caacaagtgg tatgttagct
    12361 aggtttaatg aagatgttgt aaaaaactct cctgatatag tttttataat gggtggcacc
    12421 aatgatttta ttgctggtgc gggaaataaa attattaatt ctaatataat ggctatggtg
    12481 catcagtcat attcaaaaaa tattatacct ataataggta taccattaaa accagatatt
    12541 ccaaatgtta gggaagattg gagttgtttt actgatttta atatagtatc tcaaaactta
    12601 gaatcatata gttattggat aaaaaaattt tgtatgacat ttaatactaa tttcgtagat
    12661 ttttattcag aatataataa aaatatggaa ctagaaggat ataaaaaatt atattttgat
    12721 gggttacatc caaccaaaga gggtcataga ataatggcag acatttttat taattcaatt
    12781 aataagtata tagaagagtt atagattaca ttaaaatgct tgtttatgcg tcagttgcaa
    12841 taaatacata cagtagagag gggtttatta tggattatac taaaacttat gaagagtgga
    12901 taaagggttc atattttgat gaagatacaa agctagagtt ggagaatata aaaaataatg
    12961 aaaaagaaat agaggataga ttctataagg atttagaatt tgggactgcg ggtcttagag
    13021 gaataattga agcaggaacg aatagaataa ataagtacac agttagaaga gctacttttg
    13081 gattggcaaa ctatatatta gaaaacacaa caaaagaaga aacaagtaga ggagtagtaa
    13141 tagctcatga taatagacac aagtctagac aattctgtat agaatctgca aatactttgg
    13201 cagcatgtgg tataaaagca tatatatttg atagtttgag aactactcca gaattatctt
    13261 ttgctgttag aagcttaaat gcaatcgctg gtatagtcat aacagcaagc cataatcctc
    13321 cagaatataa tggatataag gtatactggg aagatggagc acaagttatg ccagagattg
    13381 caaatgcaat aacagagaaa gtaaatagta tacatgatta tagtacaata ccaaccttaa
    13441 cggaagctaa taaaaatttg gtagttttgt tggacgaatc acaagatact aaatttatag
    13501 aagcagtaaa aagccaaatt ataagaaaag atttagttaa aaatgtaggt aaaagcttta
    13561 agatagttta tacacctctt tgtggaacag ggaatgttcc aataagaaga gcattgaaag
    13621 aagttggttt tgaaaatata attgtagttc cagaagaaga aaatccagac ccaaattttg
    13681 cagggcttga ttatccaaat ccagaagaga aaaaagcttt aaatagaggt atattactcg
    13741 caaaagaaaa aggagcagac cttgtaatag caactgaccc agattgtgat agagtaggtg
    13801 tagcagtaaa aactactaca ggtgagtatg ctttacttac aggaaatcaa attggtggta
    13861 tgctgacaca ttatataata gaaggattaa aagaaaataa taaattaaaa gaaaatccta
    13921 caataataaa aaccatagtt acatcagaat ttggagcaga tatagctaaa gcaaataatg
    13981 ttgatgtatt aaatgttctt acaggtttta aatttattgg tgaaaaaata aaattatttg
    14041 aacaaaataa aaatagaagt tatgtatttg gatatgaaga aagttatggt tacttagttg
    14101 ggactcatgc tagagataaa gatggtgtag tttcttcatt gttaatatct gaaatggcag
    14161 cattttacta ttcaaaaggt atgagtttat atgatggttt aatagaactt tataaaaagt
    14221 atggattttt caaagaacag actatatctt tgactttaaa aggtatagaa ggtgtagaaa
    14281 agataaaaga aataatatct tattttagag aaaatcaaat tgattatata aatagtatta
    14341 aagtagttga taaaaaagat tataaaaatg gtatagataa tcttcctaaa tctgatgttt
    14401 taaaatactt tttggaagat gaatcttggg tagctataag accatctgga acagaaccaa
    14461 aacttaaatt ttacatagct gtaaaaggag ctagtgatat tgaagcagat aaaaagattc
    14521 aaggtttgaa aaagtatata gatgacatgg tcgaaaaatt aaaataaaat attattattt
    14581 tataagataa ttttgtaata atatttattt agctgaaaat tataatttac tttcattgag
    14641 tagaatatgg aaatgttagt agaattgtta ttttcagctt ttatttgtgt tatttttact
    14701 taaataatta tattatagaa tgaatctgag tataattaat attgtataat gaaattaatt
    14761 tgatagaaaa ggggatattt atgtttggta tagataagaa attgattgaa tatataattg
    14821 caaaatccaa ttacagtgaa ttaagttcaa agtcagcaga agtatctttc ttcttaatgt
    14881 tgtccatatt tcctttttta atatttacaa taagttctat agcttatata ccgattcttc
    14941 atttaaataa gtatatagct ttgtttagaa atatgatgcc agaaggtgct tttgctgtgt
    15001 tatcttcaat catagtttct gcaatagaca atagaaacct gaaattttta gcagtcagtt
    15061 ttgtacttac tatgtggaca ttttcaagag cagtaaaagc tcttattaaa ggaatgaata
    15121 gagcctataa agttaaagaa actaggtctt tttttaaaat tttatctata tcatttttat
    15181 ttacaataat gcttttggtc cttatttttt tatctatgat atttttagtt tacggggaaa
    15241 aaataggtta ttttattttt aatcttgtag gattggatga gatatttata aaaatatggg
    15301 atattctaag atacactgta ggtataataa caataatagt gatatttaca cttttatata
    15361 aatacactcc aaataaaaag ttaactatta aagaatctgc gccaggtgct atttttgcta
    15421 cttttgcttg gtttttagta tcatttttat attcttatta tacaaattac tatgctaact
    15481 atgaagtaat ctatggaagt atagctgaaa taattgtact tatgacctgg atgtatttta
    15541 gtagttggtc tatcgttatt ggctatgagg taaattcaag attgtatttt agaaagataa
    15601 gacatgaaat gttaaagtaa agtatttaaa ataaaagaga gtatttagta ttataaatgt
    15661 aattgaatta ataaagaaat attgacattt aagttaaaaa gtctagaatt tttctgggct
    15721 ttttttattt ttagtataac ttgacaaatt ttatttaatg ggatagtttt aatttataat
    15781 catctttaaa aagatgacta ttgataagta agagataaaa ttggtaagta tcaaaaaata
    15841 tactaaataa aaattatagt cctaatgagt taatttctgt attttcaaat aatgcagtat
    15901 ttagtcatgt gtttttatat gtgcctgtat ttctaattac caatatatta gaataagcta
    15961 ctgtaattag atttagaaaa aagcgacata aataattata aacaaataat aaattacata
    16021 aaattaaatt tattcacaag tatatcttat aaaatatgtt ataattaata gaaaattgtc
    16081 atataattaa ttaagtagta ttattataaa taacattgaa aggtagtggt tagaatatgg
    16141 atacccataa taaatatgta aattttataa aaaatatacc tgtacctttt ttatattgta
    16201 gaattgtaaa gagacaagaa gatatagaat atcgagtaga atatataagt aagggtatgg
    16261 gcaaagtatt acaattagaa gaaggtattt gtgataaaaa tatactagat gtattgcctg
    16321 tatttaagtc taaaaaatat ttcaaagagt tgttctcaaa tgaagtggat tgtataaaaa
    16381 ggtacattcc gacacttaaa aactggataa atataaaaaa acagataata ggggattcat
    16441 acataatttt gtattttggt aaaattgtat ttgattatag acagataatc gattcctttg
    16501 ataaaaagga aaaagtagct tatattaaag acgaagaagg catatatata gattgcagtg
    16561 aaaatttaat accaatatta aataacaaca ttaaaacaac gaaagatatc tttggtaaaa
    16621 atgatataga agtatgggga gagaatacag gaaaattatt tagagatgat tatagagaag
    16681 gagtatctag taaaaaaaga tttttacaaa atctttttga atatgaagaa acatttttta
    16741 tggttgaaaa atattttttg tatgatgaag acgaactttt aggtactata gggatagtag
    16801 acaatataat atatagtggt tacagtaata gaaattataa ctcaaaagat ttaatgaaga
    16861 tgatagaaca ctcaattcca gagaatatgt tttataaaga tgtgtatgga aattatattg
    16921 gatttaattc aggttttttg aatttagctt gtatgaataa agaagaatta ttagggaaga
    16981 atagttataa aatatcagaa gaagaagctt taatagataa gatatttgaa agtgataagg
    17041 gtgtagttga aaataaaaaa gtagttacat ttgagttaaa tataagtatg aatgatgaaa
    17101 acaagtgcat tgagattaca aaaaggccgt tttttgatag ctatggaagt gttattggaa
    17161 taattggaac agcaagggat ataagtagaa gaaaaagatt agaagaggaa atggataaaa
    17221 ctaggatgga attttttgca aatttatccc atgaacttag aacgcctata aacttaatat
    17281 catcttcatt acaagtgata gaaaaaaaag aagcagattt aatagaatca aatgatactt
    17341 taaaaagaaa tttaggtata ataaaacaaa atggaaatag aatactgagg ttagtaaata
    17401 atgttataga ttttacaaaa atgcaatcag gatatttaga ttttaaacca gaagaatctg
    17461 atataattgc atttatagag gagatatgta tgtctgtagc tgattttgca agccaaaata
    17521 atatacaact tacatttgat acagaaatag aagaattttc aatgttattt gattcagaaa
    17581 aattggaaag aataatatta aatttacttt ctaatggaat taagtacaat aagaaagatg
    17641 gaaaaataaa tatattttta tatgtgaaag ataatgtatt taatatgaaa atatctgata
    17701 gtggtatagg tataccaaaa gaaaaaatag ataaaatatt taataggttt gaacagattg
    17761 acaatgaact ttcttacaga gttaaaggaa gtggtattgg actttcatta gtgaaatctt
    17821 tggttgagtt gcatgaggga agtatatctt taaaaagtca acttggtatt ggaagtgaat
    17881 ttatagtttc attgcctgtt agaagtaaaa ataatattga aaaatataat cataaaagag
    17941 aaatcagcaa tgaactaagt aaaaaattag aaatagagtt ttcggattta taagtttaaa
    18001 tataaaaaat aaaattttaa aaaagtattg acaattgatt tagaagggtt taaaataaat
    18061 tacaacataa taaataaaaa ggcgatgaat aggaagagta aatctaattc gattaccaga
    18121 gagaagagtc cgttggctgg aagacttttt aaattagagg gattgaaaac tacctaggag
    18181 ctactttctg aagtcatctg cattagtaga ttttagtaag aatagtcgtt agctgcgtta
    18241 aagtgtaaag tgagttttca tgacatatga aaactaaatt aggtggaacc gcgggaataa
    18301 tactctcgtc cttatgttat aaggatgaga gttttttgtt atttaaaaat ataaacagta
    18361 atcataataa ttatagaaaa tataaaagca atgaatagga agagtaaatt taattcgact
    18421 atcagagagg aaagttcaca ggctgaaaga ctttctaagt ttgagaaatt gaaaactacc
    18481 taggagctgt ggtctgaagt tactttaaaa agttttagta agactaaccg ttaactgcgt
    18541 taaagtgtaa agtggatttt atcaataaat gataaaatca aattgggtgg aaccgcgagt
    18601 atagactcgt ccctttatat agggatgagt ctatttttat tgcaataaaa gattgaaaat
    18661 aaaaaaaaat cggaaaatta taaatttagg aggaaaataa aatggagaat aaagtgaaaa
    18721 ttggagtact aggatatgga gttgtaggaa gtggacttat agatataata gataataata
    18781 aagaaaaaag aaatatagaa atagttggaa ttttagttaa taatttggaa aaacataagg
    18841 ataaaaaata ttctaatata ataactaata atatagatga tatatttaat aaagatatag
    18901 atatacttgt tgaagtcatg ggtggtttag aaccatcatt atcttatata aaaaaagcat
    18961 taaacaataa aattcatgtt gttacagcaa ataaagattt gttagctgaa tgtggagatg
    19021 agcttgcaaa attagcaagt gaaaataaag taagtattaa atttgaagct tcagttgcag
    19081 gaggtatacc agtattaaaa ccaataatag aatcactaga aggaaataat atagatagta
    19141 taaatgcaat tttaaatgga actactaatt ttatattatc taaaatgtat gatgagaatc
    19201 tatcttatga tatggcatta agacaagcac aagaattagg ttttgctgaa gcaaatccag
    19261 agtcagatgt attagggtat gatgctgcta gaaaactatc aatattatca actctagctt
    19321 atgacaatag agtatattgg aaagatgtgt atttagaagg aattacagat atagatgaaa
    19381 aagatattga atatgcaaaa aaattaaatt gtaaaataaa attgattggt caaagtaagt
    19441 atgaaaatga taaagtaagt gcttttgtta gacctgtttt agtagaaaaa gataatatcc
    19501 ttgctagaat agacaatgag ttcaatgctg tcatagtgaa tggagattca gtaggagaag
    19561 tttcttttgt aggtaaagga gctggaagtt tagcaacagg aagtgcggtt tattcagatg
    19621 ttatagatat aatagataat agagtttcaa gtatagattc ttttactaaa gataaaatac
    19681 aagttaataa aatagttaga gaaaagtgtg gagcacttct tagatttaaa aaatgtaata
    19741 aagatgaaat tctaaatata gttgagaatt gtttagtaaa attcgatatt ttaaatgatg
    19801 atgatgaact tgctattatg gtttatgctg attctgaata tgaaataaac aacagtttat
    19861 gtctaataaa agataaagga tactgcgaaa aaatgaataa aatgttgaaa ataagttaaa
    19921 aaagaaaaaa tataagttta tatgtaacat attttgacga ttttaatact atatagtatg
    19981 agatgaaaca aaacatctca taaaaaaatt aaaattaaag ggagagatat gttatatgga
    20041 aaataaaaaa tgttattcag aagattggta tgaaagagga gaatctacag ctaaatggtt
    20101 ccaaaatgat agagaagaat atgaaagaga agcatatgat gaagatagag aaagaagagg
    20161 ttcaaactgt ggatgttcag attcaggaga aaatagacct agaaactgtg aaagatttag
    20221 aagagaagct gagataagag aaagagaagc aagagaagca ttctgtgaat cttcagagaa
    20281 aaagaaagag gcattagcat atgaatgtga agctagaaaa ttatgggaag aagcagaaaa
    20341 atactgggat gaatattcaa aatacaacta taaaggaatc gaatatttag cagaagctgc
    20401 tagattattt gatgaaggta tggaatgtga agctagaaga aatggaaata atggaggaaa
    20461 caataataat tgttgccata aatgccataa atgtaattgt aactgctgta gaaaataaaa
    20521 aaattaattg acaaatcaat agttaaaata tatcatatta tgtataataa agagaaaatt
    20581 cagaaaaaaa taatgattag aagaaatata agtatattta ttagacaaat agtgctcagt
    20641 tagtgaggtg agtacaatat gattaaactc ccatcctcta gcttttgata gagggtggga
    20701 gtttttattt atttatatat cttaaatgag gataatattg taaaataaat gagtatgaga
    20761 ttgtaaaatt aggaggtaaa aaatgaaaag tattaaaaca tcaagtatga aagaaaaggt
    20821 agatgaaaag atattaagag agcaagtaag ttctataata gaagatataa gaaataataa
    20881 ggatgttgca cttaaaaaat ataatgagaa gtttgataga aatacaagag atgaatttag
    20941 aattactaag gaagaaataa aggaagctta taagcatgta gatgacgaat ttataaataa
    21001 cttaaagatt gctgccaaaa atataagaga atttgctaaa gctcaaaaac taagttttga
    21061 aaaccctttt gaaaaagaaa tttatccagg tgtaatctta ggtcaaacta atattccaat
    21121 agagtcatgt cttgcatatg ttccaggagg tcagtatcca ttgttttcaa cagctcttat
    21181 gcttataata cctgcaaaag tagcaggagt aaaaagaata gtggcatgtt caccaactat
    21241 gaaaaatact gaaaagataa atcctaagac attggtagct atggatatag caggtgctga
    21301 tgaaatatat gcaactggag gagttcaagc tatagcagca tttacatatg gaacagaaaa
    21361 gattaatcca gttgacataa ttgtaggacc aggaaataag tttgtaactg aagctaaaag
    21421 acaatgttat ggacaagtag ggattgattt tgtcgctggg ccaagtgaag ttcttataat
    21481 agcggatgaa acttcaaatc cagtttatat tgcagctgat ttattagcac aatgtgagca
    21541 tgatttaaat gcaagaggaa tattattgac aaatagcttg gaagtagcac aaaaagttga
    21601 aaaaaatata gaaagtatgc taaaagattt gccaacaaag gacatagcat atagttcatg
    21661 ggaaaataat ggagagataa tattggttga tgatatggaa gaagccatta aaataagtaa
    21721 tttttatgca ccagaacatt tagaagttgc agtaaatgag tataatgata tttgtgatag
    21781 attaactaac tatggttctt tatttattgg aaatctttct gctgaggtat ttggcgacta
    21841 tgtttcaggt accaatcata cattaccaac acttaaagca tcaagatata ctggtggtgt
    21901 ttgggttgga acttttatca aaacttgtac aaagcagata tttaatgaaa aagctataca
    21961 atcattagca cctgtagctg aaaagctggc aaaagaagag ggattatatg cacatgcaaa
    22021 ggctgctgag gttaggttta aaaagtagta aaaaatttta ttttggcagt cgagatttag
    22081 tgttagactg agataaggaa aacgctgaga acccgaataa atactatatt ttgtgggcct
    22141 cggcgtttct tttatatctg tatataatag gataatacta cctgtgtgtt taaatactaa
    22201 cttaatattt cttttctaaa taatgtttat gaaatagtta atatttttag ttaatagttg
    22261 aaaaaaactt ttgctaactg tgcaaattca tctgcatttg tcaatatagc agggtgtcct
    22321 ccctgactaa aaatgtgaat acttgctttt gaaataaaag ttgccatttg tttgtactct
    22381 tcttcaagat tatgacgaca catttcgtct tccttacttc ctgtaaataa aattggcatt
    22441 tctaatttac acaattcttt atgaaacaaa gggcgtttct cgtttgcaca ttgcaataga
    22501 gcttttgtat caagattaac aacattctcc caatcttttc catgacacca ttcatagaat
    22561 tttcgtgctt gaatatcttg ctttgatttt tcccttccag tgattagatt atctatgaag
    22621 ttatcattaa gagtacgtcc atcaaagcta tctgctataa ttgcttcaac taaatcggga
    22681 cgttctaatc cagtattaac agctgcccat gctcctccac ttgttccaat taagccaact
    22741 ttaccacaat tcaaatgttc aatcagtgct attgtctgta aggcttcatc atgccatatg
    22801 tcaggagaaa attgagaaac tctatccgac tgtccattac ctaaaaaatc aattaagata
    22861 catctaaaat tttctgcata taatggcaca agtgctttaa acatattaga agaaccagta
    22921 ttaccatgca ggaaaattat cggtttacct tgtccatatt ctttataaaa acaagaatta
    22981 ccttgatact gaaaatatga catatatttt cctccttttt atttgataag ttaattataa
    23041 caatataggt atgaatgaaa aacctcatgt tctttcttag aataaaaatg tgccacgcat
    23101 aaaacgtgac acatttctaa ttataaattt tgctgtttaa gtattctttg tatgcttttc
    23161 tctgtcaaaa agtatttctc tgataactgc ttgatactca ttccattttg gaaatttata
    23221 cagatttgag aattacgaga agctaagact tgtttggtgt ttgtgttttc accccaatgc
    23281 tttttgtgct cttgcttttt gggaatataa atcactttac catctatata ttcttgcact
    23341 tgctcaatca gttctttagg cagtaagtca atcgaatttt gatagctcat tttgcacctc
    23401 ctaaataatt attctttagg attagcaaag gctactgcca ctcacaatta aaaataaaat
    23461 tttttattat gtacaatagc ctttgctatg cacaagttcc aattcccata aactaaatac
    23521 tcctttctgg tttgaaaaat tcatctgaac attgatttcg cttttaagat agagttcaat
    23581 gacaaattta catttttatt atatatattc agatagataa ttgcaactgt ctttgtatga
    23641 ggatatttta ttatagtcaa tactataata tgtatttata tcatcaaact aatatgaaca
    23701 gttgaaagga atatgaacaa taaaacttag tcaggaagaa taattatgaa gcagataata
    23761 gagaaatttg attttaaagt tttattgaaa atttattgac aaatttaact tgtaaatatt
    23821 atactaaact taataaataa agtttataaa gtaaggtgtt gtctatgaaa aatatagttg
    23881 gaaaaccgca aacgataaaa aaagtaaatg aagatttaat aaaaaacatt ataaaaaatg
    23941 aaggtcctat aacaaaacca gaaatttcaa gcattactga attgagttta gctacagtta
    24001 ataagattgt agagcaatta gctttgaaaa atgaagttaa agtaagtgga ctaagtgaat
    24061 ctactggagg aagaagagct caattatttg aaataaatgc aaacttagaa cacataatag
    24121 ctttatatta ttatagaaat tgttgtatag gggtagttgc caatttatta ggtgaaataa
    24181 tttatcaaga agaatttaat ataagaatgg atacgtatga aaacgttaac caagatactt
    24241 tttttgttat agatactcta ataaaaaggg aaaaaggaaa caatataagg gctattggaa
    24301 ttggtgtccc aggagttgta aaaaaaggtg tagttaaaaa tataccaact ataaaaagtt
    24361 gggaaggtat aaatttagaa aatttaataa agagtaaata caatactaaa gtgtttatag
    24421 aaaatgatac aaatattact actattggga tttatcaaaa acagtataaa gacaaatata
    24481 aaaatatggc tcttatgtat ttagaagatg gtattggttc aggtatagtt ataaatggtg
    24541 aattgtattt aggttctaca aattttgctg gagaattaag ttatctaaat atagaatttg
    24601 gtaagtataa ctctaacaac ttaaatcttg aagattatat tatgagttta agaaaaagat
    24661 atttagaaag taaagataat aaatttaaga aagaaatttt atctataata tcaaacttta
    24721 taaggactct tgtatgtgtc ctaaatccac aagctatgat tatacagtgt agtatattaa
    24781 ccaagagtga catggagttt atagaaaaag atgtaagcaa taatgttgga gaagaaaatt
    24841 ttcctaaatt aataaaagta gagtcattga gagaaggaag tataaatgga gtaattagta
    24901 tgtgtttaaa agaaactgac tatcaatatt ccttatctaa taaaaaagga ggatattaat
    24961 gtgaaatatt tggtttcaat agatggaggg ggaacaaaaa ctaaattttg tgtaagtgac
    25021 ttagatggaa acatacttaa agaacatacc actggttcaa ctaattataa gtcagttgga
    25081 attaaaaaaa catatgaaaa tattaataat ggatttaaaa aaatattaaa agatttatat
    25141 atcgattatg acgatattga gtacactgta tttggtatat ctggttgtga ttctcctaat
    25201 gattataaga ttataatgga tgaaatatta aaaattggga ttaacaaaga aaaaatatat
    25261 ctggcaaatg atgcagtttt agctttttat gcacaagctg attcccctgg tttagtaatt
    25321 gtggctggga caggttcaat tatactggga attaaagaag atggagaaat atatagagtt
    25381 ggtggatggg ggtataattt tagtgatttg ggttctggat atgatatagg gagaaaatta
    25441 ttaaagaaag tattgcttta ttgtgatgaa tgtcatgagt atagtgattt atttagttgt
    25501 gtcttggatt tctttggagc aaatagtttt gaacaacttg catatatgat tactgatata
    25561 aatgataatg ttgaaatagc aaacttagct tcattagtga ttgattgtgc cgaacaaggt
    25621 gataaattgg ctattgaaat attaagagaa tcatcaactg aactatctaa attagctcaa
    25681 gtaatattga gaaaaatatc taatccaatg aaaatggata aaagcgaaat aaatatagtt
    25741 ttgtctggtg gtacattaaa taaaactgta tatgctcaaa tgttaatgaa taatttaaaa
    25801 acagaaaata cagataaaaa tttaaaattt atatctcaag aaaatcagcc agtatatggg
    25861 gggataagac ttgctatggc attagctaat aggagggcca agcatggata gaaaaaaggt
    25921 aatagtacaa atttttactg gaggttttaa ggctaaagaa ataaagttta atgatataaa
    25981 atgtaaacta ctagaattat tggactgtat tgatatagaa aaggttatca tgggatggag
    26041 tgtagatgaa gaattatatg tagaaactaa aaaactatta aataaatata atgttgaact
    26101 atatctttgg ttgccatgtt tttctgaaat aggattactt gaaaaaagta atttactaat
    26161 tgattatatg gggaaggaag tcaagggcta tgctttacaa gaggatgaaa attttgagtt
    26221 ttattgccca aataataagg aaaatataaa aaatataaag aaaatatata gtacttattt
    26281 tagtgatatt aaatttgatg gaattttttt agataaaata aggtatggtt ctttttcgaa
    26341 taaactaaat ggtgttttta attgtttttg taaagattgt ttaaatatat atgaaaaaaa
    26401 taatattgat aaagagtcgt taatgagaga aatgaataat gtgtctaagg gagttataga
    26461 taatgaagat actccatttg gtataacaga atacattaat ggaaaataca aatttaaaaa
    26521 taaaatatgg gaagattttt ttgaaacaaa aaatcaaaat atatacaagg cattattaga
    26581 gataagtaat tattttaaaa gtaagggatt gaaaataggt atagatactt tttctccttt
    26641 tatttcttac tttacaggtc aagatttaga aaaattacaa gaagtagcag attttataaa
    26701 accaatgatg tatagaatta caaaagctcc agctggttta ccatttgaat ttgaaaggtt
    26761 tattgatgaa tccatacata agaataaaga gattggaaaa agaaatttct tagatatttt
    26821 aggaattaag gagtatgaag gaaatgtata ccctatagaa tttgtactag aggaaatcga
    26881 ttttatgaca agaaatctta ataaagatat atatgtagga gttgaaataa ataaaaagga
    26941 aattatagct cctgttacac ctaagtacat aagtgaaaat atttcaaata taaataagac
    27001 aacagtaaaa ggatatgttt tatcttggga tttgttatca gcaccaaaag aaaatattga
    27061 tgaaattata aaatggtttc ggaattagtg aggtgatata gtgagtaaga tattggaaat
    27121 gcaacaaata tataaaagtt ttggaaaggt agatgtttta aaagggataa attttgagtt
    27181 agaaaaggga gaagtaagag ctcttttggg agctaatgga gcaggaaaat ctacacttat
    27241 taaaatttta ggaggagttc attcccaaac taaaggtaaa gtaattttga ctggtaatga
    27301 aataatgttt aaaaatccac atcattctaa agaaaatggt attagtataa tttatcaaga
    27361 attaagcttg ataccaacgc ttacagtact tgaaaatatt tttcttggta gagaaatttt
    27421 aaaaggaagt gtgtttttaa acaagaaaga catgcttgag gaatatatga aaatttgtga
    27481 ggattttgat tttaatatag acccacatat agtagtttct aatttaagtg tagcaaacca
    27541 acaaatggtt gagataatga aagctgtttc atgtaattct gaaattatca taatggatga
    27601 acctacaaca tcacttacta ataatgaaaa agatgggcta tttaaaataa taagtagact
    27661 aaagtctaaa ggtaaaacaa tagtctatat ttctcacata ttagaggaag tttttaaagt
    27721 atgtgatagt acaagtataa tgaaaaatgg aattatgatt ggaacttatg atgtagagga
    27781 tttaactaaa ttaaagataa ctcaacttat gacaggaaat gataatcaca aacttattga
    27841 gaagaaggat tatacatttg caaaatatga agagccacca gtactagaag taaagaatat
    27901 aagctggtct aacaaaataa aaaatgtttc atttaaagtt tatagaggcg aagttgtagg
    27961 tcttgcaggt cttgtaggtt caagaagaac tgaaattata aatttgatat ttggtataga
    28021 taataaagat agtggagaca tttttatcaa tggtaaaaaa gtagacataa cttctcctaa
    28081 ggttgctata aaaaacaaaa taggattgat tcctgaagat agaaaaaatc taggattaat
    28141 tttagaacaa gctatataca caaactcatc atcagtacaa attgataaat tcaagaaatt
    28201 cttgtttata gatagaaata aagaaattga gttttctaaa aaaggtgtta aggaattagg
    28261 aataaaagtt agtgatgtaa agcaagaagt aaaagagctt agtggtggaa atcaacaaaa
    28321 agtagtagtt tctaagtggt tagagaaaga tttagattta ataatatatg atgagccaac
    28381 aaagggaata gatattgctg caaaagaaga tattttcaat acaatcaaag aattttcaag
    28441 taaaggaata ggagtaatat ttatatcttc tgatttagaa gaagtaataa gagtaagtga
    28501 tagaatttta gtaactagag aaggttctat tgtagatgat ttaaaaaatg agaatataca
    28561 ggttcaagat ataatgaaca gtatatttaa tgtataaaaa atgaaaatgg aggactgaga
    28621 tgaagaaagc ttttgagaag ttaaatttaa gagattatgg agtattatta ggttttttag
    28681 ctttatgtat agctataagt attgcaactc catcattttt aggtaaacaa aatatactta
    28741 atcttttacg acaatcttct ataattggaa taatttcagc aggtatgact tttgttataa
    28801 tatctggaaa ctttgatata tcagttggag cagtagcagc tcttgcaggt gctataacaa
    28861 tgaaatttgc gactggtgga actaatttgt ttgcatccat gttcttaggt gtagcgattt
    28921 gtgcagtaat aggattaatc aatggtatag tagttgcaaa gataaatgta ccatcattaa
    28981 tagccactat ggctatggtc actattgtaa gaggattgct gttgatgctt acaggaggat
    29041 atccaattac tgaaaatata ccaatacttg attacattgg aaatggatat ttgtttaata
    29101 taccaatacc agtagtaatt ttctttatag tggtgttagt ttcgtttatt gtacttaata
    29161 aaactaagtt tggtagatat gtttattctg taggagggaa tcaagaagca agtaaactta
    29221 atggtataaa tgtagattct cacaaagtga aagtgtttat tattaatgct gtacttgcag
    29281 gaatagctgg aatcgtacta acaggaagac ttgggactgc aactgcgatt gcaggtgaag
    29341 gatatgatat ggatgcaatt gcatctgtag taataggagg tacatcagtg gcaggaggtt
    29401 ctggttctgt acttaaaact gttataggag tattacttat gagtgttata aacaacagtt
    29461 ttaatcttct tggaatagat gtatatttcc agtacatatt taaaggatta ataattttag
    29521 cagcagttgg atttgattct tatagcaaga aaaaacttgc ttcaagataa aaaataaggg
    29581 ggattttttt atgaaaaaat taatgaaaca tttagcattg ttgctatcac ttgttatgat
    29641 atttggttta gttggttgtt caaatggtgg tgacaaagaa aaaaatggag aaaagaaaat
    29701 agcagtatta ctaccgggtt caacaggtta ctttgtagca actaaacaag gtatagatgc
    29761 aaaatctaaa gaattaggtg taagcgtgga atatgcagat gctcaatggg atgctagtaa
    29821 acaattatca caagctgaag attttatggc taaaggggta gacatgattg cattatgtgg
    29881 agttgattct gctgtaagtg agagaatagc taaagctgct aatgattcag acgttcctat
    29941 agtagcattt acaaattcta taggaagtaa cccaactgga gaatttaaag gtttagttac
    30001 atatatagga caaaatgagg aagaaacagg agcattaact ggaaaaattg ctaaaaactt
    30061 attaggagaa actggtggga aagctgtatt aatagaagga gtaccaggaa ctactccaca
    30121 agtattaaga aaaaaaggtc ttgaaaaaga attaaaagat agtaatatag aaatagttta
    30181 taatcaaact tcaaattggg agaaagagca agctttaaaa gtaacagaag atttaattca
    30241 aaagaaaact gattttaatg ttataatatg tcaagatgat aattctgcta caggtgcagg
    30301 tcaagcttta aaagatgctg gtcttaagga taaagttaaa gtcataggtt tgggtggaag
    30361 taaagatgga ttaaaagcta taactgatgg gttaatagat ggtacaactt atatgtctgc
    30421 tgtagaagaa ggtggattag tcatagaaaa ggcatctaaa ttccttaaag gtgaaaaaat
    30481 agaacctgtt acacaaatta aacaagttga agttaacaaa gataatattt cagagttcaa
    30541 gggtgaatgg taaattgtca tagataataa ataagatttt tagagttact ttagaaacta
    30601 tataaagtaa ctcttttttt aatttaattt agtgataaat tattgaatag tatttctaaa
    30661 caaataaaaa attaatataa acaaagactt aattatacta aattataagt aaaactaata
    30721 taaacttatg gaaaaaagga aaacgtctaa agtattggaa ttactatagt gtaggtgtgg
    30781 tattaaaaaa acataaaaaa acataaaaaa attgttgaaa aaaatataga aattttgtat
    30841 aattaaagat ttgaaaagtg cggtatacaa agccaattct tttgtatata atatatataa
    30901 attcagaaaa aggaagggat atgtatggcc aggcggttat ttttagaaag gattggactt
    30961 atatttttag gttcagcaat attagcattt ggagtttata atttttatta tttaaacaac
    31021 ataacagaag gtggagtgtt aggtatttta ctactgttaa aaaatttatt caatatacaa
    31081 ccagcaatag caaatgttgt aatagatggt ttactacttt tagtaggata taaatttttc
    31141 ggtaaaaaat tccttatata ttcaatagta gcttctataa ctttttcagt gttatatgac
    31201 ttatttgaag ctataggacc tctagtacca caatcacaaa atatgctttt atcaactatt
    31261 ttggcaggtg taactgttgg aactggtgta ggtatagtag taaaagcagg ttgtgcatca
    31321 ggaggagacg atgctttagc attagtaatt tctaagacta catctttgaa catagggcaa
    31381 gtttatttag caacagatgt tattgtattg ttgttatcat tattttatct atcagcgttt
    31441 gatatctttt attctttgat tgctgttaca attagtggca aggtaattga ttttatttat
    31501 tatcatggta aaagtttgga tatggatata agtaatgata tagttccaga atgttaatat
    31561 aaattaaata actttagatt ttattagggg tggcagattt gccacctttt ttgtgtctaa
    31621 atctttatag aaagtataat cccatctagg tttttgtaaa tctcaaatat agaattatgt
    31681 tggaatgact gggaatacga ttgctagatg tgcattttaa aaaccaaatt ttatatttat
    31741 gaaatactaa tcattaatgg atgtttctta atcctatctt tatacctaaa atgataagat
    31801 aaatgaagta gcaatacaaa actaaaattt gtaaaagaga ttaaattaaa tggaggagct
    31861 aaaatgttgg atatagttat gatagcattg ttattcatag gatttgtttc catgaagtta
    31921 cttgctgatt ggtgtgggaa acaaactgaa aaaaaataat gtaatgtatg gagggattac
    31981 ctatgtggtt tctggcagtt gtaattataa tgttaataat atatttggta tatgcgctta
    32041 ttaatcctga aaaattttaa acagtataag gctaataagt aagttgaatt ggggggaaca
    32101 atttttatgg tgcagatagt aatagtgtta gcgattttta tgattttagt aatacctatg
    32161 ggcaagtatt tatatcatat agctactaat caaaaaacat ttggagatag actatttgat
    32221 aaagtggaca attttatata taaggtatgt agtatagata agaaaaaaga aatgaactgg
    32281 aaacagtatg cattagcttt attatttaca aatgcagtta tggtatttat aggatatatc
    32341 atacttagaa ctcaaagtat gcatattttt aatccaagtg gaattaaaag tatggaacaa
    32401 ggactatcat ttaatacaat aataagtttt atgacaaata caaatcttca acattattca
    32461 ggtgaatcag gactttcata ctttagtcag atgacagtga taatatatat gatgtttaca
    32521 tcagctgcaa caggatatgc ggctgctatg gcatttgtaa gaggtctagt cggtaaaaag
    32581 aaaacattgg gaaattttta tgtagattta attaggataa caacaagagt acttttacca
    32641 ggagctttaa ttattgggct tatattagtt acacaaggag taccacaaac ttttgctggg
    32701 acagaaacag tgactactat agaaggaaag cttcaagata tagctagagg tcctgtggca
    32761 gctcttgaat caataaaaca tttaggaaca aatggtggtg gattctttgg ttcaaattca
    32821 tcacacccat ttgaaaatcc aacaataata tcaaatatag tagaaatatt atctatgatg
    32881 atattaccag gagcttgtgt tgttgcattt ggtcacatga taaagaataa aaaacaaggt
    32941 tgggttgtgt ttggcgcaat gtcaatcata tttttaatag gtctagtagt gtgctttaaa
    33001 gcagaaagtg caggaaaccc tattttatca caattagggc ttaatcaaag tatgggaagt
    33061 atggaaggta aggaagttag atttggtata gcacaatcat cattattcac aacagtgact
    33121 acttccttta cgacaggtac agttaataat atgcatgata cactgactcc tttaggagga
    33181 ttagtaccac ttttaaatat gatgctaaat gtagtatttg gtggtaaagg cgtaggtctg
    33241 atgaatatgt tgatgtacgc tataatagca gtattcttat gtggattaat ggtaggaaga
    33301 acaccagagt ttttaactaa gaaaatcgaa ggaaaagaaa tgaagcttat tgctttactt
    33361 attatattac atccactttt aatactaatg ttctctggtc tttcagtagc aataccagca
    33421 ggacttgaag gaatttcaaa tcctggattc catggattat cacaggtatt gtatgagttt
    33481 gcatcttcag cagctaataa tggttcagga tttgaaggtt taggagataa cactatgttt
    33541 tggaatataa caacaggtat agttatgttc tttggaagat atgtgtctat tatagtacta
    33601 ctagcaatat caagtttgtt agcatctaaa aaagctgtaa atgaaagtat aggaacactt
    33661 agaacggata attttacatt tacaatagtt ctagtacttg ttgttttaat tgttggtgct
    33721 ttaacatttt tcccagcctt agcgcttgga cctatttcgg agcatctagt gttgtggcac
    33781 taaaaaattg ggagggagta aagttttatg gaaactaaaa aaacaaagtt tattacaaaa
    33841 gatattttca aaacttccat tatagaagct tttaaaaaat taaatcctaa atatatgatg
    33901 aaaaatccag ttatgtttgt tgtagaaatt ggatttatag taacattgat acttacaata
    33961 gtacctagtt tgtttggtga tgaaggcaat aacttaagag cttataatgg gattgtaaca
    34021 ataatcttat ttataacagt cctttttgca aattttgctg aagctgtagc tgagggaaga
    34081 ggtaaagctc aagcagatac acttaagaaa actagaaaag atacagtagc aagggttata
    34141 gatacgttag gaaatgaaaa aatgataagt gcaagtgagc taaaacttgg tgatattgtt
    34201 ttagtaaatg ctggagaagt tattccaaat gatggagaag ttatagaggg catagcttct
    34261 gtagatgagt cagcaataac tggagaatct gcacctgtca tgagagaatc aggtggagat
    34321 ttcgcatctg ttacaggtgg tactacagtt gtaagtgact ggttaaagat aagaataaca
    34381 acaaaaccag gagaatcgtt cttagataaa atgatagctc ttgtagaagg tgcttcaaga
    34441 caaaaaacgc caaatgagat tgctttaaat actttgttag tagggttaac acttatattt
    34501 atggttgttt taatatctct ttatccaatg gcaaactatg caggtgtaaa gattccaatt
    34561 tctactatga tagctctttt ggtatgttta ataccaacta ctataggtgg attgttgtca
    34621 gctattggta ttgcaggtat ggatagagta actagattta atgtaattgc aatgtcagga
    34681 aaagcagtag aagcttgtgg agacgttgat actatgattt tggataagac aggtacgatt
    34741 acttatggga atagacttgc atcagaattt atagcagttg gaaatgcaga ttcaaaagat
    34801 ttaataaatt attctgttat gtgttcatta aaagatgata caccagaagg aaaatctata
    34861 gttgatttag gtatgaaatt aggttcaaca ggtaagacaa aagaggcaga ggaagctgag
    34921 tttgtagaat tttctgcaca aactagaatg agtggtatta acttagctga tggtagagct
    34981 ataagaaaag gtgcttatga tagcataata aaaagagtaa aagaatctgg tggtacagtg
    35041 ccagaagatt tagaagaaaa tgtaaatcga gtagctaaac taggaggaac acctttagta
    35101 gtgtgtgtag ataatgagat atatggaatt atctacttaa aagatacagt aaaatcaggg
    35161 cttgtagaaa gatttgctag acttcgagag ataggaataa agacaataat gtgtacaggg
    35221 gataatccct tgacagcagc tacaattgca agagaagctg gagtagatgg atttattgca
    35281 gaatgtaaac cagaagataa aatagatgca ataaaaaaag aacaattaga gggtaaaata
    35341 gttgcaatga caggtgatgg aacaaatgat gctcctgcac ttgctcaggc agatgtaggt
    35401 cttgcaatga atagtggtac aacatctgca aaagaagcag caaatatggt agatttagat
    35461 tcagacccaa ctaagatatt ggaagttgtt gaaataggaa aacagctttt aataactcgt
    35521 ggggctttga caacatttag tatagcaaat gatgttgcaa aatattttgc gattatacca
    35581 gctatattta ctcttgcaat acctcaaatg gagatattaa atgtaatgaa actttctacg
    35641 tcatttagtg cgatattatc agctttaata tttaatgcta taattatccc atgtttaata
    35701 cctcttgcaa tgaagggagt aaaatataga cctatgaaat cacaagctat gttaatgaga
    35761 aatatgctta tatttggtct tggtggagtt atagtaccat ttttaggaat aaaattaatt
    35821 gatttattga ttacaccttt agtaatggtt cttaatttag gttaataaat ggaggatata
    35881 aaaatgaaaa cattaaagcc agcattactt gtaagtattg tattgttagt tgtttgtgga
    35941 cttgtatatc cacttgtttt gacaggtgta agtcaagttg catttaaaga taaagccaat
    36001 ggaagtatga tagaagtaaa tggtgtaaaa gtaggttcag aacttattgg tcaaagcttt
    36061 acagatgcga gattctttaa gggaagagta tcatcagtaa actataatac ttatacaaaa
    36121 gaagatttag taccagataa agatggaaat acatcttatg gaggtgtatc atcagggtct
    36181 tttaattatg gagctacaaa tccagaactt catgatagag tacaaaaaga tatagaaaag
    36241 tttttaaagg ataatccaac tgtcaaaaga gaggatatac caacagattt acttacagca
    36301 tcaggttcag gacttgaccc taatataagt ccagcctctg caaaaattca gataccagct
    36361 atagcaaaag cgtctggaat atcagaaagt aaattacaaa aaattgtaga tgataatact
    36421 tccaaaaaac tttttggagt tttaggtgaa gatagagtta atgtattaaa agttaatgta
    36481 gaggtcgcaa aaatattagg tcttatatag tattttgtgg aattttagca acaaaatatt
    36541 actcaagatt taatttaaag gttaaatttt aaagagtgaa aatcgataat gattttcact
    36601 tttttatttg aatattacta atatttggaa taaagtgatt gtaagtataa aatccaaaaa
    36661 aaggttgcat tatcaaaatg ataatactat aatatattta tcgttatcaa tttgataata
    36721 gatttggaca tataggagga aatagtatgt tatataataa cgcattagag ttgataggaa
    36781 acacacctgt agtaaggctg aataatttag gctgtactaa tgggtgttct aacatatatg
    36841 taaaattaga aaaagtaaat ccagcaggaa gtataaaaga tagagctgtt tatgaaatgt
    36901 tagagggctt agagcaaaga ggagaattaa aaaagggaga tgtactagtt gaagcaacta
    36961 gtggaaatac tggtattgca ttatctatga taggaaaatt aaaaggatat gaagtagtaa
    37021 tcgtaatgcc cgaaacaatg agcgttgaga gaagagattt aatgaaggct tatggagcaa
    37081 atttggtgct tacagatggt aaagctggaa tggcaggttc catagaaaaa gcaaatgaac
    37141 ttttaaaaga aaatccaaac tataaaagct taaaacaatt tgaaaataaa gataatccaa
    37201 atgcacatta taaaacaaca gcagttgaaa ttatgaatga tgtcaaagat ttagatatat
    37261 tcgtatgtgg agttggaaca ggtggtactt taataggaac tgcaagatat ttaaaagaac
    37321 aaaatccaaa tataagagta attgcacttg aaccaaaaaa atctccagct atatcagaaa
    37381 acaagactgg acctcataaa atacaaggaa taggtgctaa ctttgttcct gaaaattatg
    37441 attctagtgt agttgatgaa gtaatattag tagatgatga agatgcattt gatacagtta
    37501 aattacttgc agcaaaagag ggaattttag tagggatatc ttctggagca aatatatttg
    37561 gtgctataga gatggcaaaa aagtatccag ataaaaagat agttacagta gctccagatg
    37621 gagttgataa gtatatgtct atgggaatat tttaataatt ttatttgagg gagtgaatac
    37681 tttgtttaag aaaataaata aagatattga atatataatg aagaatgatc cagcagctag
    37741 gtctaagata gaagtttttt tactttatcc atcagttcat gcaatgataa tgcataggat
    37801 ggctcatgct ctttataaga agaagaagct ttttacagca agattaatat cccagatatc
    37861 cagatttatg actggcatag aaatacatcc tggtgctaaa atgggggaag gtatattgat
    37921 agaccatgga atgggtgttg taattggaga gacagcggaa gtaggtaata gggtgacaat
    37981 atatcaagga gctactttag gagctacagg aaaagatact ggaaagagac atccaactgt
    38041 tggtgatgat gtattaattg gtgctggaac aaaaatacta ggacctttaa atataggttc
    38101 aaattcaaaa attggtgcaa attctgttgt tgttaaggat gtacctaatg gtgcaacagt
    38161 tgttggtata ccagcaaaaa tagtaaaaat aagaaaccta gaacctgtaa aaaagaataa
    38221 aaaagaagtg tcctatgagt atgatgaatt agataatgta tattatatat aggatttata
    38281 taactataaa ataaacttta taaaaattat tttaaaaggt atttttttca aatttgagga
    38341 cataataaaa aagaactgaa tgttacagtt ttggttcatc aatctttgat aaataagatt
    38401 ttaaatttgt agcgtctagg aggattttat tatgaaagca aatgttaatc aagatacttg
    38461 tataggttgt ggattatgtc catcaatatg tccagaagta tttgatatga aggatgatgg
    38521 gaaatcacat gttatagttg atgaagtacc aagtgatgct gaagaatcag cagcagaagc
    38581 tagagaaagc tgtccagttg atgcaataga tgtgcattaa taaaataaat gcctataaaa
    38641 attgaatttt caatttttat aggcatttgt cttttattca gttagtattt caacacctgt
    38701 ttctgtaact aaaaccatac attcccattg agcagataat ttaccatctt ttgtataaat
    38761 agtccaatta ttttcttcat caacaaaaat ttcgtgagtt ccttcattta ccataggttc
    38821 tattgtgaat atcatcccag gaaccaatag catctcagtc ccttttttag atacataact
    38881 tacaaaaggg tcttcatgaa agcttaatcc aactccatga ccacctattt ctctaacaac
    38941 agagtatcca tttttctttg cataagagtt gatagcatca cctatatctc ctaaaaatcc
    39001 ccatggtttg gcaacttcaa gacctttttg gacacattcc tttgtaactt gaactaattt
    39061 ttttgcattt tcattaacat tacctatcat aaacattctt gaagcatctg aatagtatcc
    39121 attaaaaata gtagaaacat ctacatttat aatatctcca tcttttaaga taatgtcctt
    39181 acttggaata ccatgacaaa cttcattatt tactgatgta catacacttt taggaaatcc
    39241 attatagtct agtggagcag ggatagctcc attttgtagt gtaaagtcat gaaccaactt
    39301 atttatatct tctgtagaca ttccaatttc gattttatct gaaatataat ccaaaatttt
    39361 tgtgtttatt acagcacttt tttttatttc ctcaatttga ctttcatttt ttataatatc
    39421 atgagttggt acaatatgac ctaacttagc aaatgaatct attttattat ccatatccat
    39481 atgacatttt ttatattttt tagtacttcc acaccaacag ctatcatttc tatttaactt
    39541 cataactttt catccttctt ttattattta tttaaattat gggttacata aactatttta
    39601 aaacataacc attataaata ttataacata aatactaaga aatcctttat agatagtgat
    39661 ttattcaaag tataaattat tatatggtta ttgttgatga aaagaggata gttaaatgta
    39721 ttattggata ttagcgcact taatagttta gttcaagttt ttcaagaaaa tcatatgtta
    39781 gaggacaatt ttcctttaaa gtattttttg aatcttcatc aagataataa tgtacaaatg
    39841 attctgcaaa aaattcttct ataaacttgc ttatatatgc atgtgcaact tgcttagggt
    39901 cataaagctt atatctttcc tgagcaaata cttccataaa ttcttcagaa tttgattttt
    39961 tatttaaaac atttttatct atagcatgtg cagtttcatg taattctaaa ttttttgatg
    40021 aatgtacatt tgcatagcta ggattactat aacctatttt agccactata gaattatttc
    40081 tatatatacc aggtacatct ttccaagtct tgcctgatct tacccaacat ggaggtaatt
    40141 gatattttaa atcactaaat tctggttcat cagttagatt tgaatttatt aattttattt
    40201 ttatatcctt ttctttaagt gtctgtaaat atttaatatt tatttttgca agtctgcttt
    40261 tcatattttc aacttcatct ttatcataat tcaagtcatc aggaagtata agcatttgtt
    40321 caattatatc tatactactg tcttttatat tttcagattc ttcatcaaat ttatattgaa
    40381 gagtattatt ttcatagata gttatatttg tattattttc tatagaataa gagtgaatat
    40441 cctctaaatc taaaatattc atttgttgta aaatatgttt tgtttcgcca ctccatacta
    40501 ctaaagaaag tgaattaaaa ttaattagtg gattttcttt tgcttttata tcattgctta
    40561 tatctacatc aaatacatat tcaattgagt cttctatgtt aagactatct gtattctttt
    40621 taatatataa atacgcttgt tttaagtcta tataaatctc acctaaagat tcgtcataaa
    40681 attctgataa attattagta aagagttctt cacttaaaag ttcattttta tcagttatac
    40741 tttcaattaa aatattaatt tcttttatca tatcgtaaat acttattttt ctatttgctt
    40801 tttcactaga tacattgcat ggcgcaagag caatgcaata aaaatctttt tcttttttat
    40861 aaaaggcttt aagtgatttt gataaaagtg taaagtctac acctatctgt aagttgacct
    40921 taagtgagtc attttgtaat aattcagtat tatttctttt agctgtattt aaattgtttt
    40981 ccataatcat tgcccccttt ttattagggt atcataattt ttttatatgt gtcaatttgt
    41041 ttttttgaaa attataattt ttttgaaaat tttatttttt ataatttgtg aattttttat
    41101 tatagaaata aatatgttat tattatgtca aaatttagca ttagattcat gtagagtatg
    41161 ttttatacat atattataat taattctttg aagattgcat attcaaaata cacaccattt
    41221 tttttaattc tataatataa tatttatata tttaatgtta ggatgtgatt taaggtgtat
    41281 tttacatata ttataagatg taaagatgat tctctataca ctggatatac cagtaatata
    41341 gttagaagaa tgaatgaaca taagttagga attaattcaa aatacacaag agcaaaggga
    41401 tttgaaaaac tagaagttta ttttgtgacc aacacaaaaa gcaatgctat gaagttagaa
    41461 tactatataa aaaaattaac tagaaataaa aaattgtcta taataaaaaa cccaagtata
    41521 cttataaatt taattgataa taaagaagat tatattattg gtaagaaaat agaacaatta
    41581 acataaatat ttatagtaac attataatgg gtgcatatgg tgtaaaaact tgacaataaa
    41641 tactattgta atataatgaa gttataaata tagtaaatta aaatagctag gggagccaag
    41701 agctgagagg tataccgacc cttacacctg atctggataa taccagcgta ggaaagctta
    41761 gtaaaaattc aagtatgtat tatttgtgat atatgctatt tctaagctat acctattgta
    41821 ggtatagctt ttttaattaa gttatttaaa ttaaacttta ggaggcaaca atgagtaatt
    41881 ataaaatacc aacacttaca atagccggct ctgattcatc tggaggagct gggattcagg
    41941 ctgatttgaa aacgtttagt gcaattggta cttatggtat gagtgtaata acagctataa
    42001 cagcacagaa tactaaagga gtttttgctg tagaggattt aaataagaaa ataataaaaa
    42061 aacaaataga ggcagtcttt gaagatatac ctccaagagc tgtaaaaata ggaatggttt
    42121 caagtcctga gattatactt gaaatagttg agaatctaaa gaaatacaat ccaaaatatt
    42181 tggttgtgga cccagtaatg atatctaaaa gtggatatta tctattaaag ccagaggcaa
    42241 aagaaaactt aattaagtat ttgataccac ttgcatacat aattacacca aatataccag
    42301 aggcagaaga aataacagga ataaaaatac ataatgtaga tgatatgaag agagtaggag
    42361 aagaaatact acaacttgga cctaaatttg tacttatgaa aggaggtcat ttagatggag
    42421 aagcagtgga tattttagtt ggtaaaaata tatttaaagt ttataaaagt gaaagaattg
    42481 ataaaaaaaa tacacatgga acagggtgca cattatcttc tgcaataaca tcttatctag
    42541 cattaggata tgaaataaca gaagcagtaa atctaagtaa aatctatata acagaagcaa
    42601 taaaaagaag ttttgatata ggtcatggag taggaccagt acatcatttt tataaatttg
    42661 agtaataaaa aaatattgga ggtaaaatat gtataattta attaaagatg taaaaaaatt
    42721 aaatccattg gtaattcatt atactaataa tgtaactata aatgattgtg ctaatgtaac
    42781 tttagctgta ggagcaagtc ctcttatgag tttttcatat gaggaagtag aagaaatggt
    42841 aagtgtagca aactctgtag taataaatat aggaactatg aactcaaata tgttggattt
    42901 attcctatta gctggaaaag cagcaaataa gtacaataaa cctgttgttt tggacccagt
    42961 tggagtattt gcaagcaaag cgagagcaga acttacaagt agacttttaa atgaagtcaa
    43021 atttagtgtt gttaaaggga atgtatcaga aataaagttt ataggtggct ttaatgtaaa
    43081 gggtaaaggt gtagattcat ttgatgaaga agaagattct actgagataa taagaaagat
    43141 tgctgaaaag cttgaatgtg tagttgtagc aactggaaaa atagatataa taactaatgg
    43201 taaaggtaca tataaaataa acaatggaac tgataaatta aaaggaatta caggaactgg
    43261 atgtatgact gctagcttga ttgcaagttt tatggctgtt actgagaata tattagaagc
    43321 agcaacaatg ggtgttctta caatgtcttt aagtggggaa ttagctaatt taaataatcc
    43381 accaataggt acatttaaag aaaatcttat gaatgctatt tatcaaatgg atatagatac
    43441 tttaagtaaa aattctaata ttgaattttt aaattaataa agagtaaggg agacttaaaa
    43501 tgattgataa agaatcttta aaaaaatgtt taaagttgta tttagtaact gactctgaaa
    43561 tgcttaaagg tagagacttt tataaatgtc ttgaagatgc aatatcttct ggaataacaa
    43621 ctgtacaact tagagaaaaa aatgcttctg gaagagagtt tttaagaaaa gctatgaaac
    43681 ttagagaaat aactaaaaga tatggtgtta agtttataat aaatgataga gtggatatag
    43741 cacttatttg tgatgcagat ggagtacatg taggacagag tgacattgat gttagagagg
    43801 ttagaaagct tataggaaac aataaaattc taggagtatc agcaagaact ttagaagaag
    43861 ctatttgtgc aaaaaatgat ggcgcagact atttaggtgt agggtctata ttcacaacat
    43921 ctactaaatt agatgcaaaa tcagcttcgt ttgaaactgt taaagaaatt aaagaaaaag
    43981 tagacatgcc atttgtacta attggaggta taaatttaga caatatagat aaacttaaat
    44041 gtttagaaag tgacgggtat gctataatat cagctatatt aaaagctgaa gatatctcta
    44101 aagaagtgga aaagtggaca ttaaaaatat aaaattggct ctggtagtga aaaaaatgga
    44161 aaaatttgat ataatctaag agtaaaattt aagcaattat aaatgataaa cttttctaca
    44221 tatacttttt aatcaagata tatgtagatt tggttaaaaa ggagctataa atgattagga
    44281 tattgttagt gtgtgttgga ggcatgtctt ctaccctatt ggtaaataaa atggagaagg
    44341 atgcaaaaaa aagaaatata gactgtaaaa tatgggcagt tggagaagga gatataaaat
    44401 cggagcttga taactttgat attttacttc ttggaccaca acttagattt atgcttgatg
    44461 acgtaaagtc tatagttgga gatagagctc cagtatctat aatagatatg gtaaactatg
    44521 gcacttgtaa tggtcatgct gtgttaaatt cggttttaga aatattaaaa taaataataa
    44581 aagtggattc tatataatag agtccatttt tattatttgt tattaatagg cttaaaactt
    44641 agcttaccat ttcttttttt aatctccaca tagcaagtga aaaacttgaa cagcacaata
    44701 ttaaaaatag taggataaaa ggcagtatat ctccaataag aatagtctca ccaaatatta
    44761 agctacgtaa agcgttaata acatgggtaa atggattgag catcactgct acttttaatc
    44821 ctccagataa actttctata gggaaaagag ctgaacttaa aaagaaaata ggaagtacaa
    44881 ttgcagtcat aattgtttca taaactattt catttggcaa taataaactt atagaataag
    44941 ctagacttga taaaaagaag gctgtcataa atatcagtac tatcataagt aggattccac
    45001 caatgccaga ttctatcctt actgagaaga atatacttac tatacacaaa atagttactt
    45061 ctatgaaaga aactaagata gcttctaata attgaccaag gacgattgaa tacctgctga
    45121 taggtgcaat taagactcta tagaaacttc cactgttctt cattataaag tttataatac
    45181 caccactact acaagaagaa aacacaacca gtacaatgat acctggtagt ataaaagcag
    45241 tataattatt gatatttata ttattcatag tttggtttgc aatagaacta taaagcacaa
    45301 gccaaagaaa aggttgtaat atagtaacta caaatgagat tggattttta aaacgccact
    45361 tcatactacg ccataagata tttaacattc ccattcctcc tttaagcttt ttttagaact
    45421 tgtaagtgct aaaaatacat cttcgagact tggctctaca atttctattg catcaaattc
    45481 tatatcatgt tctaaaagcc atttatttat taaagtaaaa gcagttctac tatcgtttac
    45541 acttataaaa attgaatttt ctcgtacgct cataaacttt actaaaccag tacttttaat
    45601 tgaatcttta tattttttta tatcttcagt attatgaaaa gttatacgta gtatattttg
    45661 tctaatgtaa ctacgtaaac ttgatggtgt tccttgtgct aaatcctttc cattcttcat
    45721 aatacaaata ttatcactca attgttcagc ttcttcaaga taatgagtag ttagaaatat
    45781 agttgtgcca tactcatctc taatttttaa taacatatcc cacatagatt ttcttgaatc
    45841 gacatccata ccaacagttg gttcatctaa aaataggatt ttaggagatg ataccatatt
    45901 catagctatg tccaatctac gttttacacc ccctgaatat gatgaagtag gatattttaa
    45961 gtaactagat aagtcaaact tatcaattaa agagtctatt ctttgttttg caatctgtgg
    46021 ttctacttta tacattttac tttgaaatac catattttcc ataagggata aatgttcatc
    46081 aatagagatt tgctgtgcta cacaagcaat ttgagtacgt atccaagaag aattatctac
    46141 taaatctttt ccaaacattt ttacatttcc agatgtaggt ttgtaaaagg tagtcaaaat
    46201 atttataaga gaagatttac cagcaccatt aggaccaagt aaagaaaaaa tttctccagc
    46261 atttacatta aagcttagac catttaaagc tttcacacca tttttatatt cttttactaa
    46321 attgtctatt tcaatcgcta acatatatta ttcctcctct ttaagtggaa atattatctc
    46381 tgtaatatag ttatctgggt ttccttttat caacatacct ggtcctttaa taaatacttc
    46441 tctccaagga gtttgtattt ttatattatt ttcatgaata tatttaaata tcatttcata
    46501 cgtttttggc aaattactat aagagcctgt gtgagtaaaa aataaagctt ttgttttagg
    46561 aaattctttt gtagttatac ccatacgatt tggagtttca gcagttggaa cacataattc
    46621 catttctgca acaccagttt tttggtcaac atcatagtag caaaagaatg gtgcaccgtt
    46681 agactttcct tttatagctt taaatacatt tggaaaatac tttgttgcct cagtcatagg
    46741 tccattataa cgcatggtag ccactgtgac tgattcgata tttttgattt caattttgca
    46801 attcatttgt ttacctccta atgtgtgttc atattcttac tagattttta agcattaata
    46861 catataagat tttgattagt tgaaaacata taatcttatc tcgtttgctt gttttcaagt
    46921 ctaacataac ataaaatata tatcctctca tttgatgctc cattttgtaa agttattatt
    46981 taagctttac tttagatttt ttagcaaatt aaaataaagc aatttataaa ataagtattt
    47041 acaaattaag tgtattaatc gtataataca cttaatagga tactagataa agtctgaaat
    47101 aaaggcgtat ttttttaaag taagtgtact atcgtattaa tacactagaa taggaggaat
    47161 catgaatttt gaattagata atacaactcc catttatttg caaatagtaa agtatataaa
    47221 gagacaaata gtaacaggag agttgaaacc aggagagaca ataccatcaa gaagagaaat
    47281 ggcacttaat ctaaaagtaa acttaaatac agttcaaaga gcatataagg agatgggtga
    47341 tatgaatata ataaatactt ttaaaaatta tcaaagcagt gtaacagttg atgaaaatat
    47401 attaaaaaat ttaaaattag agcttataaa tgaatcacta tctgttttta tagaagatat
    47461 gaaagcaata aatgttagca aagaagaagt tttaaaaata atagaagata agtattagtt
    47521 ttttaacaaa tagaaaactt agtttagaaa gtttatttat aagcatattg gatgtggagg
    47581 atagtaaata tgatagaaat aaagaatgtc agcaaaacat ataaaaggat gcaagggctt
    47641 aaaataagaa agatagaagc tttaaaaaat gtaagtttta atatagaaaa gggaaaaata
    47701 actgcattac ttggtataaa tggtgttggt aaatcaacca tgttaaaagc aatagcagga
    47761 cttataaaca ttgatagtgg agaaattcgt atagatggag aaaaaataaa tgaaaaagta
    47821 tacaataaat tggcttttgt tccagatgta caatctcact ttagcaatac aacaataaaa
    47881 gaaacatttg aatttatgga aattttttat tcaaagtgga ataaagaaaa atcaaaagaa
    47941 atgatggaca tatttaaatt ggatgaagat gaaataattg ataacttgtc aaaaggaaac
    48001 attgcaagag taaaattaat acttggattt tgccaagacc cagagtacat acttcttgat
    48061 gaaccattta caggaattga tttgtttaag agggaagagt ttataggagt aatagcgcaa
    48121 tatatggagg aaaatcaagc cattatcata actactcatg agatagtaga gatagaaagt
    48181 ttagttgatg aggttgtaat tcttgatgaa gggcagatta taacttcatt taatgcagaa
    48241 gaattaagag aaagagaagg taaatctata ttagataaga tgagggaggt atataagaat
    48301 gaataaactt ctatatctaa taaatgtaga tttgagaaga agcaataagt tttatatagc
    48361 ttatatatca tttttttcat taattacact tagtttaaat ttattcgaaa ttaataaatt
    48421 taaaaattct aaatttatta tgaacttagc aatagaagat tttggaggta tattttatgg
    48481 actagggata cttagtaatc ttggttttat ccaaagtata ttgttctttg ggatattggg
    48541 actttttata tactatattt ttatgtggaa aagagagttc ttttcaaata atcaaagtat
    48601 ttatacactt atgatgttac ctcaaaataa gtttaagatt tgtatatcta aatcaatagc
    48661 cttgataaca atgatatatg gttttttgat aagtcagaca gcaacattat ttatatgtaa
    48721 atatatattt aatttcattt ttagaaatat gcctataatc aatatgaact ttgccaaaga
    48781 tttatattat ttaaacttga agagtatacc aattgatttt atctctttta tggctattta
    48841 tgtattttta ctacttatag ctatttctat tgtaaattgc tgtatattat ttatcttttc
    48901 ctatataaat aaattttatg taattttaat cactttgctg attatagcag gcttatattt
    48961 ttcaacaata tatataaata taatcacttt atttagaaaa tattataatc ttataggatt
    49021 tcaatttaac aatttagtag cagggttatt aagtttttta attataatgt ttattctaaa
    49081 tggaatatct tatttgctaa ttaaaaagaa agtatctctt taaggagggg tggtatgaaa
    49141 ttaaaatcta aaatatctat atttattata tttttgactt tagcaatata ttttagtata
    49201 ggtttattaa ataatgaaga taatttaaag ataaaaacta taaaaggtga ctctaatgaa
    49261 ttagaccata taaacataaa ttttggatat gctttgaatg gatatataaa ttcatattat
    49321 acaataaatg gaagtaacaa aaccaaaaag actgaattaa taaaactaca aaaggatagt
    49381 aagaacacaa ataatttaat tgatgtatct agtggttcag atttaattgc tcatgttgga
    49441 tttgaaatga atgaggagtc aaaagatata aactttgtga tagatgagaa aaaagaagat
    49501 ttagaaaaag gtgtatttcc atcagaaggt agtgataaag aaattgaata tgaaaaatta
    49561 gatatgaata attttacaag gacaagatat aaagtagata aaagtacaga tgattattat
    49621 gcaaagatac tagcatcaaa aagatataaa aaatacttat atgtatctgt actttatgct
    49681 acaagtgatt catcagaaaa taacaaagaa tattcaagta ctatagatat aataaaaatt
    49741 aatccagaaa ataaaaaaat caagactata aaaagtataa atttaagtaa ttatttttcc
    49801 gaaaaatacc aaaacataga gaacataggt gtaagttatg ctagcaaata tgaggataag
    49861 atgtatattt tagtaaatgt actaaataca aacataggtg ataatagtaa ttctaaattt
    49921 catttacttg agtataatct tgaagaaaat aaggaaagca taatggaatt aaaaactgat
    49981 agcaaaatgg ctttagcaaa agcaaagtta gaagctaata aattatatat ggtaatgtcg
    50041 aatgattatg ataatagttc aattacagag ttaaatttac ttacctataa tatattagat
    50101 aaaagcttag atgaagataa atatgtttta gataatagag aaaaaagagg aattagaagt
    50161 attgaaattg attcaaataa aatcgttgca tatacatcaa ggctaaactc tatattatct
    50221 tgggatgata aatttatgct atatataata aataaaaatt ctaaggaaat tgtatatgaa
    50281 ggagaattac aatttaacag ttcaaatagt atgttagaat ttgaaataaa gtaggtgagt
    50341 tgatgaaaga tttaataaga ttattcgaat ttgaattaaa aagaaatata aagaattata
    50401 tatttataat aatttgttgt tgttcttttg taattttaaa catagtaaaa aatttaaatg
    50461 actataatta cataatagaa aatgcagtta aaagtgaaca gttaacaaaa atcggaaata
    50521 cgatagaaac ggtaaatgtt acaggtttct caagctttag aaatataatg ggttctacag
    50581 aatcgtggtt tatgtttggt ataattgcat gtatttgcta tgcttttttt atttggtata
    50641 gagactttaa tggtagaagt aaatctatat atacacttat aatgctacct aaaaatagaa
    50701 tcaatattta tatatctaaa ttattaaata tattatttct agtgtatagc tatacagtag
    50761 tacttacaat atctttgttt attgcaagta agttgttgcc tagacatatg cttggtaatg
    50821 tcacaaacta tggttttgta caagaaacaa tatatgagtt aaaaatgtta cttccatata
    50881 gctttgaaat actatttgta gagtatatat ttttattgat aggatttgta tctgtagtat
    50941 ttacatcaat tcttataaat aaatctattt ataaagtaag cactttaata agttttctat
    51001 ttttagttat agaaatttta gtgtttataa tttctataga atttattata ccttacgaat
    51061 acagtgatgt atttactgtt ctatattcaa gtataaacat atttgtatgt agtcttatat
    51121 ctaataaact tttgaagcaa aagattgact tttaggaggg atattatgaa agcaaaaaat
    51181 ataggaaaat atacaatatg ttttataata gtatgttttt taatgattac tatgacctta
    51241 atattgagtt attttaataa ggataaacta tctgtaaaaa ctttaaaagg caatgtaaaa
    51301 gatataggga gagtaagtgt agtatataca cctgatataa gcaaattttc ttatgaggag
    51361 gtaattataa gtaaaaatgg agtaagaaat aatacaaacc caaaatcaag aattagaaat
    51421 gattatttaa atattgacaa aaaatacagt gactttgtta atgataaagg aaaagaattt
    51481 atatataaag atgatttgaa tataggagaa gcgtatacct ctgttaagtc tgatttagta
    51541 caaggaatga atgctttaaa tgattgtata aaggtttcaa ataaaaattt aaaaagtggg
    51601 gtagaagaaa attttgatat taatttaaat aagtctgatt ttaaagaaaa tagttggaaa
    51661 accttattta acaaaatata taaaggtaat ttatatatgg taattagtga aactaatatt
    51721 tcaggttcta aagtcaataa tatttgtata ttaaagatag atataaaaaa taagtcttat
    51781 aaattattaa atagatttaa tttaggatta cagaatggag aacaacaaaa tatcaatgaa
    51841 attaaatttt ctattggaag taaattatac ttagaaatag taaataataa aagtaaaaat
    51901 ggatatattg aaggacatga tagttactct aactttatta tatatgatat agaagataac
    51961 acttttaata taagtaataa atttatggat aatctaaaca aagaaaagaa tgcaaatcca
    52021 aaggagattg gcttattaag taaaactaag ctagattata tggtaaaaaa taataaattg
    52081 aatcttatag ttacggatat gagtaattcc ataactaatc ttgtttatga tattaattct
    52141 aatgagatta aattagaaga ttatgagata cttgatttaa aagtagatta taatgaagca
    52201 tcatctggag ttaggaaagt taagctactg gatgataaga tatattctat ttcaggtatt
    52261 aagaacagta tatcaggaga attaaaagga tttaaagggg ttgttgatgt agtcggaact
    52321 aagccagtaa aatttcaagt atttgatatg aaacttaaaa agaatattta tgaagctgag
    52381 ctaataaatg gagatataag tttacaagaa aagttatttt ttgttgcaaa ttaagtgtta
    52441 gaattaattt tagaacttta aacttttata tgtatcacag ataagtataa gtaagggagt
    52501 gtctcaaaat aaacttttta gctcatgaga cacttttttt atatgaaatc aaatatattt
    52561 tcattgttta gatttatttt gataatgaaa aaaa
//
LOCUS       DAEOTL010000018        50090 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEOTL010000018 DAEOTL010000000
VERSION     DAEOTL010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50090
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.018"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            6..82
                     /locus_tag="KRH82_001386"
     tRNA            6..82
                     /locus_tag="KRH82_001386"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:40..42,aa:Arg,seq:acg)
     gene            95..170
                     /locus_tag="KRH82_001387"
     tRNA            95..170
                     /locus_tag="KRH82_001387"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:128..130,aa:Val,seq:tac)
     gene            246..659
                     /locus_tag="KRH82_001388"
     CDS             246..659
                     /locus_tag="KRH82_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654675.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            968..4399
                     /locus_tag="KRH82_001389"
     CDS             968..4399
                     /locus_tag="KRH82_001389"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBG8654676.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLEDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            4641..6569
                     /locus_tag="KRH82_001390"
     CDS             4641..6569
                     /locus_tag="KRH82_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBG8654677.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGALSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            7022..7486
                     /locus_tag="KRH82_001391"
     CDS             7022..7486
                     /locus_tag="KRH82_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBG8654678.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            7493..7987
                     /locus_tag="KRH82_001392"
     CDS             7493..7987
                     /locus_tag="KRH82_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBG8654679.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            8003..9028
                     /locus_tag="KRH82_001393"
     CDS             8003..9028
                     /locus_tag="KRH82_001393"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBG8654680.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            9015..11462
                     /locus_tag="KRH82_001394"
     CDS             9015..11462
                     /locus_tag="KRH82_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBG8654681.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            11642..13015
                     /gene="radA"
                     /locus_tag="KRH82_001395"
     CDS             11642..13015
                     /gene="radA"
                     /locus_tag="KRH82_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBG8654682.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            13018..14088
                     /gene="disA"
                     /locus_tag="KRH82_001396"
     CDS             13018..14088
                     /gene="disA"
                     /locus_tag="KRH82_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBG8654683.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            14177..15271
                     /locus_tag="KRH82_001397"
     CDS             14177..15271
                     /locus_tag="KRH82_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBG8654684.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            15400..17577
                     /locus_tag="KRH82_001398"
     CDS             15400..17577
                     /locus_tag="KRH82_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654685.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(17763..18608)
                     /locus_tag="KRH82_001399"
     CDS             complement(17763..18608)
                     /locus_tag="KRH82_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8654686.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            18825..19991
                     /locus_tag="KRH82_001400"
     CDS             18825..19991
                     /locus_tag="KRH82_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBG8654687.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            20013..21659
                     /locus_tag="KRH82_001401"
     CDS             20013..21659
                     /locus_tag="KRH82_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBG8654688.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            21756..23129
                     /locus_tag="KRH82_001402"
     CDS             21756..23129
                     /locus_tag="KRH82_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8654689.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNHIG
                     VIFASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LDELNTK"
     gene            23574..24527
                     /locus_tag="KRH82_001403"
     CDS             23574..24527
                     /locus_tag="KRH82_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBG8654690.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            24565..25527
                     /locus_tag="KRH82_001404"
     CDS             24565..25527
                     /locus_tag="KRH82_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBG8654691.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            25552..26538
                     /locus_tag="KRH82_001405"
     CDS             25552..26538
                     /locus_tag="KRH82_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBG8654692.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            26551..27597
                     /locus_tag="KRH82_001406"
     CDS             26551..27597
                     /locus_tag="KRH82_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBG8654693.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            27764..29494
                     /gene="lpdA"
                     /locus_tag="KRH82_001407"
     CDS             27764..29494
                     /gene="lpdA"
                     /locus_tag="KRH82_001407"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBG8654694.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEKLVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            29912..32860
                     /locus_tag="KRH82_001408"
     CDS             29912..32860
                     /locus_tag="KRH82_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654695.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            32838..33302
                     /locus_tag="KRH82_001409"
     CDS             32838..33302
                     /locus_tag="KRH82_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8654696.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            33415..33717
                     /locus_tag="KRH82_001410"
     CDS             33415..33717
                     /locus_tag="KRH82_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8654697.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            33779..35143
                     /locus_tag="KRH82_001411"
     CDS             33779..35143
                     /locus_tag="KRH82_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBG8654698.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            35178..35651
                     /locus_tag="KRH82_001412"
     CDS             35178..35651
                     /locus_tag="KRH82_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654699.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGKLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            35823..36473
                     /locus_tag="KRH82_001413"
     CDS             35823..36473
                     /locus_tag="KRH82_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBG8654700.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            36647..37579
                     /locus_tag="KRH82_001414"
     CDS             36647..37579
                     /locus_tag="KRH82_001414"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBG8654701.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            37853..38566
                     /gene="ispD"
                     /locus_tag="KRH82_001415"
     CDS             37853..38566
                     /gene="ispD"
                     /locus_tag="KRH82_001415"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBG8654702.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDKNCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            38563..39048
                     /locus_tag="KRH82_001416"
     CDS             38563..39048
                     /locus_tag="KRH82_001416"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBG8654703.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    39143..39351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            39415..41130
                     /locus_tag="KRH82_001417"
     CDS             39415..41130
                     /locus_tag="KRH82_001417"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBG8654704.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            41252..42697
                     /locus_tag="KRH82_001418"
     CDS             41252..42697
                     /locus_tag="KRH82_001418"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBG8654705.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            43135..44616
                     /locus_tag="KRH82_001419"
     CDS             43135..44616
                     /locus_tag="KRH82_001419"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBG8654706.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            44837..44992
                     /locus_tag="KRH82_001420"
     CDS             44837..44992
                     /locus_tag="KRH82_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654707.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            45137..46534
                     /locus_tag="KRH82_001421"
     CDS             45137..46534
                     /locus_tag="KRH82_001421"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBG8654708.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            46519..46932
                     /locus_tag="KRH82_001422"
     CDS             46519..46932
                     /locus_tag="KRH82_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBG8654709.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            47038..47796
                     /locus_tag="KRH82_001423"
     CDS             47038..47796
                     /locus_tag="KRH82_001423"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBG8654710.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLREVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            47809..48546
                     /gene="rlmB"
                     /locus_tag="KRH82_001424"
     CDS             47809..48546
                     /gene="rlmB"
                     /locus_tag="KRH82_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBG8654711.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            48549..49076
                     /locus_tag="KRH82_001425"
     CDS             48549..49076
                     /locus_tag="KRH82_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBG8654712.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            49141..49788
                     /gene="sigH"
                     /locus_tag="KRH82_001426"
     CDS             49141..49788
                     /gene="sigH"
                     /locus_tag="KRH82_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBG8654713.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            49862..>50090
                     /gene="tuf"
                     /locus_tag="KRH82_001427"
     CDS             49862..>50090
                     /gene="tuf"
                     /locus_tag="KRH82_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBG8654714.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNR"
BASE COUNT        20610 a         5209 c         9389 g        14882 t
ORIGIN      
        1 aaaatgcgct catagctcaa ctggatagag tgtctgacta cgaatcagaa ggttaggggt
       61 tcgagtccct ttgggcgcac catatgaata gcgagggatt atagctcagc tgggagagca
      121 cctgccttac aagcaggggg tcacaggttc gagccctgtt aatcccacca gtgcaaacct
      181 ctagtaaaac tactagaggt tttatttttg attgaaaaag tttttatatt taggaggtaa
      241 aaaatttgta tatagtaata ggaaatgaaa tagttgatag tgaagaactt aaaataatta
      301 tagataaaaa tagtgaattt aaagttgaaa aagatttaag taaaagcaca aaaagagaag
      361 atgtaatagc atatcagtta agtatagatt taaattacct agattctctt ataaatgagc
      421 aatgtaattt agccagtcta tctgatgaag agaaatttga tgaatatatg actttgtctg
      481 atgaacttgc actggattta gaagagttaa tgccaaaata tacaataata aatgctagag
      541 catataaatt agacgaggta tatggaattg taaaaataat actagctgta gcgtatgcag
      601 atttagggca cttaaaactt tctgatgtag taaagaggct atctagacaa gtagattagg
      661 atatgaatat gaactatatt aaaaaaatgt ataaaatctt acgtaaagat gaaaataatt
      721 atgtaaacat agaaaaaaac agtataaaat caagtcaatt gtagaaattt tcacataaat
      781 tcatctgaaa ttctataaaa aatgccttaa ttttaatgag gtaaatcgag tttacacagt
      841 ctaaaaatta cttatattta taaatttatc ttattaatta aggaactttc ttaaacatct
      901 tcaaaaataa agtattttag tctataatct ttaatattac acaaacaata aaggagaaga
      961 atagagtatg cttaaaaagt ttaataaaat actagtggct aatagaggcg aaatagctat
     1021 aagaatattt agagcctgtt cagaattggg gataaaaagt gttggtatat acagtaagga
     1081 agataagtat ggattgttta gaacaaaagc ggatgaatca tatttgatag gagaaggtaa
     1141 agggccaata gatgcatatt tagatatgga tggaataata gacctagcaa agagaaaaaa
     1201 agttgatgct atacatccag gatatggttt tctagcggag aatgcagaat ttgctcgtaa
     1261 atgtgaagag aatggaatta cttttatagg accatcatct aaggtaatga atatgatggg
     1321 ggataagatt aactctaaaa aaatcgcaaa agaagttaat gttcaaacta taccaggagt
     1381 agaaaaagca ataagaagta ctgaagaagc aaaggaagtt gcaaacaaaa taggatatcc
     1441 tgttatgata aaagcatcta atggcggtgg tggtagaggt atgagaattg tacatcgcga
     1501 agaagactta gagcttgaat atgaaactgc ttgtagtgaa tcaagaaaag cttttggaga
     1561 agatattata tttatagaaa aatatatagc tgatccaaaa catatagaag ttcaaatatt
     1621 aggtgataat tatggaaata tagttcactt atatgaaaga gattgttcag ttcaaagaag
     1681 acatcaaaaa ataatagaat atgcaccagc tttttcatta gaagataaag taagaaaaga
     1741 gatatgtgaa gatgcagtta agttatcaaa acatgtgggt tattctaatg cgggaacatt
     1801 agaattttta gtagatgcaa atggtgggca ttattttata gagatgaaca caagagtaca
     1861 ggttgaacat actgtaacag agatggttac aggaatagat atagttcaaa gtcaaatact
     1921 aatagcccaa ggttacagct tagatagtga agaaattaat ataaaatcac aagatgatgt
     1981 ggaaataaga ggttactcta tccaatgtag aataactaca gaagacccta agaataaatt
     2041 catgcctgat acaggtaaaa ttcaagttta tagaactggt tcaggatttg gtataagact
     2101 agatggagga aatggattta caggggcaaa cataagtcct cactatgata gtttattggt
     2161 taagacaata tcttgggata gaacattcca aggagcaata aataaaacta taagatctat
     2221 aaaagaactt agagttagag gtgttaaaac taatgtagga ttcctagtta atgttttaaa
     2281 taatcctata ttctcaaatg gtaaatgtag tactaagttt atagatgaaa atccagattt
     2341 atttgaaata acagaaagta aagacagagg aacaaaatta cttcaattta taggagatgt
     2401 aattgtaaat gataatgctt gtaaagaaaa accattattt gatgcattac atgacccaag
     2461 aatggataag gatggttcaa aatcggaagg aagtaaaata cttttcgata agttaggtaa
     2521 atctgcatat atagaaaaga taaaaaatga taagaaatta ctattaacag atacaacaat
     2581 gagagatgca catcaatcat tattagcaac aagaataaga acatatgact tattaaaagc
     2641 tgctaagcca acagaaaaat atcaaaagga tttattctca cttgaaatgt ggggaggagc
     2701 tacttatgat gttgcatata gatttttaaa agaatctcct tggcgtagat tacaaaagct
     2761 aagagaagaa ataccaagca taatgttcca aatgttgctt agagcatcaa atggagttgg
     2821 atataaaaac tatccagata atgtaataga agaatttaca aaagaatctg ctagacaagg
     2881 tatagatgta tttagaatat ttgattcatt aaactgggtt gaaaatatga aaccatctat
     2941 taatacagct ttagaaactg gaaaaattgt tgaagcaact atgtgttata caggtgatat
     3001 actagataag actaaaacta aatacaatct agaatattat attaaaatgg cacaagaatt
     3061 agaaagcttg ggagcagaca taatagcaat aaaagatatg tcaggtcttc ttaaaccata
     3121 ttcagcttac acactagtta aagagttaaa gaaaaatgta aaagcaccaa tacatttaca
     3181 cactcatgat acaagtggaa atggtgtagc aacttgttta atggcgtcag aagctggagt
     3241 agacataatt gatgctgcat tagaatctat ggcaggactt acaagtcagc catcacttaa
     3301 tgctatagta gaggcactta agaatacaga gagagataca ggaatagatt tatttggata
     3361 tgatgagtta ggaaaatatt ataaggattt aagaaaagtt tataataaat ttgaaagtga
     3421 tttaactaat tcttgtgcag aaatatataa ttttgaaata ccaggaggcc aatatacaaa
     3481 cttaaaacct caagctgata gtttaggatt agttaataga tttgatgaag ttaaagaaaa
     3541 atataaagaa gctaatgaag ttgtaggaga tataataaaa gtaactccat cttcaaaagt
     3601 tgtaggagac ttagctatct ttatgactaa aaataaatta gataaagaca atataataga
     3661 agaaggtaaa aatttatcat tcccagattc tgttgtggat tactgtaaag gtatgattgg
     3721 tcaaccagaa ggtggaatac caaaagattt acaagaggta gttctaaaag gtgaagaagc
     3781 tataacagta agaccaggtt cattattacc agcagaagat tttgatgaaa tagctaaata
     3841 tctaaatgaa aagtatgata taaatgctaa tataagaaat gttataagtt atgctttata
     3901 tccaaaagta tatgaagatt atatcaaaca tctacaacat tataatgata tatctaaact
     3961 tgaaagtgat gtattcttct atggattaaa taaaaatgaa gaatgtgaag tagaaataga
     4021 agaaggtaag gtattaacaa taagattagt tgaaattggt gaagttaagg aaaatggatt
     4081 tagaactata ggatttgagt taaatggaat ggttagagaa gtagaaataa aagataagaa
     4141 tttctctgga aaaattaata atgttgaaaa agctgatatg aatgaccctc ttcaaattgg
     4201 agcaagcata ccaggaaaag ttataaaaat aatggttaaa gaagaagatg aagtaaaagc
     4261 aaatcaacca ttaatcgtta tagaggctat gaagatggaa actataatag ttgctaagac
     4321 tgatggagta attaagtcaa tcaaagtaaa agaagatgat atggttgaag ataaacaatt
     4381 attaatgata atgaagtaat ttaattaaaa taaattaaaa agcactctga aatgtttaat
     4441 aaaaaatgtt ttagagtgtt tttatttatt ttaattaaat atttgttaaa aaaaagagga
     4501 caattacctc cagatgtaga aataaagcta gtaaggaaaa tgttatctaa aaattctaaa
     4561 tatagtaaat attttccata atatttctta ggaaataaca gcaaagataa aatacataaa
     4621 tttaaaaggt gggtgcttat atgaaggttt atgatagtaa aatgttgaga aatgtagcgg
     4681 tattaggaca tagcggatgt ggaaaaacaa atctaatcga aactatagct tacacagcaa
     4741 acactaataa gatacctaaa ttaacagaca aggtaaatat gacttatagc atgggattaa
     4801 tacctataga gtataatgat tataagttta acttattgga taccccagga tattttgact
     4861 ttagcggaga cgttgtgtca tctcttagag caagtgatgc agcaataata gtaatagatg
     4921 caacagcgcc tattcaagtt ggtacagaga aatcattaga actaactgag agtattccta
     4981 agataatgtt tataaataaa atagataatg aaaaggcaag atacaaagat gcaatagcaa
     5041 tgttaagaga aaaatacaat aataagatag ttcctatgat aagtcctata tacaaagata
     5101 aaaactttgt aaagttacat aatgtttttg aaaacataga tgatttagaa ggtgaattta
     5161 aggaacaagc tatgagtgtt aaagaagcat taatggaact tatagcagaa actgatgacc
     5221 aaatattaga taaatatttt aatggagaag aactaactac agaagagata caaaaaggta
     5281 ttattatagg tatacaaaga ggtgatatta tacctgtaat atgtggttca actataaata
     5341 atataggcac aaaggaaata ttagatacaa tatcaagtta tttagaacct atctttacag
     5401 aggaaagcaa accatttagg ggattagtat ttaaaactat ggttgaccca tttgttggaa
     5461 agatgtcata tataaaaatt actgagggtg cactttctaa ggataaagat gtttttaata
     5521 taaataaaaa tgtaaaagaa aaaatagcta atatatatac attgagaaat agtgaattag
     5581 tagaaataga aaaagctaaa gctggtgata tagtagttat aactaaagtt aattctctaa
     5641 aaacaggaga cactatatct gcagataaag atgcagaagc tttagaaaag atagattttc
     5701 ctaaaccaca aatatattat gcagtaactc ctaagaataa aggtgatgaa gaaaaagtag
     5761 catctgtatt aaataaacta gtagaagagg accctacatt acattggtat agaaatacag
     5821 agacaaaaca agcactttta ggaggtcaag gagaacttca tataaaaaca attaaaaata
     5881 aaatgaaaga taagtttggt gttgatgttg aattgaatga ccttaaagtt ccttatagag
     5941 aaactataaa aggaacagct gatgtacaag gaaaacataa aaagcaatca ggtggtcatg
     6001 gtcaatatgg agacgtaaaa ataagatttg aaagatgtga atctgatttt gaatttacag
     6061 aagaaatatt tggtggttct gtaccaaaac aatatatacc agcagttgaa aaaggtttaa
     6121 aagactctat gcaaaaaggt atattagcag gatatcctgt tacaaacata aaagctacgc
     6181 tttatgatgg ttcataccat gatgtagact cttctgaaat ggcctttaag atggcagcaa
     6241 gtgcagcctt taaaaaaggt atggaagaag cacacccaat actactagaa cctataatga
     6301 aacttaagat aactgttcca gaagaatata tgggagatgt catgggtgat ataaataaga
     6361 gaagaggaaa aatatttgga atggaaccag atgacaaagg gaaacaaata atatttgcag
     6421 aagctccaca agcagagaca tttaaatatg caatagattt aagagcaatg acacaaggta
     6481 gaggatactt tgaaatggaa ttagagagat atggagaggt tccatcacag tttgcagaaa
     6541 aaataattgg gttagctact gcaaagtaat gaacaaaata aatagaaaaa taattaatat
     6601 atattattaa aaatattttt agggttttaa ctaggtatag gtttatgtta ggtaaactta
     6661 tacctagttt ttatacattt ttgatgaata aaaaaatata taatactttc ttaaatattt
     6721 taataaaaag aaagtatttt tttattatta tttttacaaa tgtttagtaa taaagatgag
     6781 aaggtatatt taaaatataa agtatttaaa gttctgaaat ctaatcatga agcaaaaaat
     6841 tagcatttgg ttatcaataa atataataaa taaaaactca taattaatga aagaataaat
     6901 tcatatctaa atttctataa aaaatttaaa tttatacaat ttagggcttt aaaaatttaa
     6961 ataataggtg taaaataata gtcaaagaaa gtcaaaaata aaaaggtgtg tggtgatatt
     7021 aatggcaact atgacagata taattgaaaa atttattaaa gatttgatgg aagaagataa
     7081 tagcatacaa attcaaagaa atgaactagc aaacttgttt agttgtgcac catcacaaat
     7141 aaattatgtc ttaacaacaa gatttacaat agatagagga tattacattg aaagtaaaaa
     7201 aggtggcgga ggatatgttc aaatagaaaa aatacgaaaa agtaaagatg ggcatattag
     7261 agaactacta aatgaaaaaa taggaagtca gatatcctat aaaaaagcaa aagaattatt
     7321 agaaggttta aaagagtcgg atttgattaa cgaaagagaa ttaaaattaa tattatatgc
     7381 aatagatgat aaatcattgt gtatgccaat atatgaatta aaagagaagg taagatctaa
     7441 tattttaaag aatataataa taggattatt tagtatagag gagtgataat ttatgctatg
     7501 tcaaaaatgc aataagaata aagcatctgt atattataat aagatagtca atggagaaaa
     7561 aacagagatg tatttatgta gtgagtgtgc aaaagagaat acagaaatga attttaactt
     7621 agatatgcct ttttcaatga tggatatatt ttctaattta ggttttcaac ctaaaaaaga
     7681 acttgaggaa aagctagttt gtcctaaatg caatacaaca tatagtgagt ttaagaataa
     7741 tgggagattt ggatgtagtg aatgttataa tgcatttagt agtcaagtaa atccaatgct
     7801 tcaaaatata catgggcata tagaacatac aggaaaagca cctaaaaaat ctttttataa
     7861 gataagtgta gaaaatgaga ttaaagaact aaaagaagat ttagatagag ctataaaaaa
     7921 tgaagagtat gaattagcag ctcaatttag agataaaatt aaatatttaa aaggttctat
     7981 tgactaagat tggagtgata ttatgaaaga gaacatagtc atgaaatcaa gagttaggct
     8041 agctagaaat ttaaataact atccatttcc aaataaatta gataaagaat gtgccatgga
     8101 aataatagaa aaagtaaaaa atgcgtttat taattctaac ttagaacaaa aagaagaatt
     8161 tgatttctat aaaattgaag atttagacca atctaaaaaa atgcttatgg ttgaagaaca
     8221 tataataagc ccagatttag cagaaaatga taaaagtgca gttatagtaa aaaaagataa
     8281 aactataagc ataatgataa atgaagaaga ccatataagg atacaaacta tatgtgatga
     8341 tttaaactta gaatatgcat atagtgtagc aaatgaaata gatgatttgt tagaatcaag
     8401 tttagaatat gcctttaaca caaagctagg ttatctaaca tcttgtccaa ctaatacagg
     8461 aacaggaatg agagcttctg taatgatgca tttaccagca ttaagtcaac taggctatat
     8521 ggatgaactt tataaaattt catcacaaat aggtatagca attagaggga tatatggaga
     8581 acgaacagaa gcattgggaa atatatatca aatatctaat caacttacac ttggaagaac
     8641 agagtctaat attatagaaa atgtaagtgg acttacaaaa gatgcaattt caaaagaaat
     8701 aaaagctaga gaaatattgc aaaaaaaatt aggtataaaa ctagaagata aaatatttag
     8761 atcgataggg acacttgaaa attcaagagt aatgagtagc gcagaggcaa tgagccatct
     8821 atcaaatata aaaatgggaa tagaaatgaa ctatatagat aaactagatt taagggctat
     8881 agaacaactt atgataggta tacaaccagc gcatcagtca ataatgtata agagtgatga
     8941 tgttgagaat agagatataa atagagcaac atatattaga gaaactttgg aaaaattaag
     9001 aggagggatg aattgtgaac ttcaatagat ttacacaaag agctaaaaag gcaattgatt
     9061 tagcgtttga atctgctaaa agtctaggac acaatattgt cggaagtgaa catatacttt
     9121 taggtctttt aagagaagaa gaaggtatag ctgctaaagt tctaagtaaa gttggattta
     9181 cagaagctta tttagaaggc aaaatagttg atatggaagg taagggagaa gaaatctcag
     9241 aagatatagt attaagtcca aggagtaaac aaatacttga attatcagga atgtttgcaa
     9301 ataaattaaa aacaaattat attgggactg agcatatatt attagcaatt attcaagaag
     9361 gtgaaggaat agctaataag attttaaatt atgctggagt aaatgatagg actttagccc
     9421 aattaacaat tgatatgatg ggtattagtg ataaaaatca atacaaagca gaaaatagtt
     9481 acacgggcaa ccagaatcaa gcagaatcta aagtacttga taagtatgga agaaatctta
     9541 cactatatgc aaaacagaat aaaatagacc ctgtaatagg tagagaaaaa gaaatacaaa
     9601 gagtaataca aatattaagt agaagaacta aaaacaatcc agtgttgata ggagacccag
     9661 gtgtagggaa aacagccata gctgaaggtc tggctacaaa tatagcctta ggaaatgttc
     9721 cagaaacact aaaaaacaaa actttatact ctttagagat gggttcatta ttggctggag
     9781 ctaagtatag aggagaattt gaagaaagaa ttaaagaagt tgtagatgaa gttgttaaaa
     9841 atggaaacat aatcttattt atagatgaga tgcacacaat aataggggct gggtctactg
     9901 gagaaggctc tatagatgct tcaaatatat taaagccagc cttagcaaga ggagaaatac
     9961 aagttatagg tgcaactaca attgatgaat atagaaagca tgttgaaaaa gattctgctc
    10021 tagaaagaag attccaacca gttatggtag atgaaccaac taaagaggac tcaataaaaa
    10081 tattagaagg attaagagat aaatatgaag ctcatcataa agttaaaata actgatgatg
    10141 ctataaaggc agctgtagaa ttatcaacta gatatatatc agacagatat ctgccagata
    10201 aagctataga cttgattgat gaagctgcat caaaagtaag attaaaagaa aatacacctc
    10261 cttcagaaat aaaaaaatta gaactagaaa tagaaaatat agataaagaa aaagaagaag
    10321 cagtaagatg tcaagacttt gagaaagcag ccaaaataag agatgaacaa ggtctactta
    10381 aaaaacaatt agaagatgtt agagaaagat ggaacaagtc atctaaacat tcagatttag
    10441 ttgatggaga agttattgct gaagtagtgg gcttatggac aggaatacca gttaataaaa
    10501 ttcttgaaga agaggctgat agacttttga gacttgagga aatactgcac aatagagtta
    10561 taggtcaaga acaagcagta aaatctattt caaaggcaat cagaaggtca agagcaggtc
    10621 ttaaagaccc taatagacca attggttcat ttttattttt aggtccaaca ggagtaggta
    10681 aaacagaatt atctaaggca ttagcagaag tgcaatttgg agatgaaaat caaataatta
    10741 gaatagatat gtctgaatat atggaaaaac atgctgtgtc aagaatgata ggttcacctc
    10801 caggttatgt aggtcatgat gaaggtggtc aattaactga aaaagtaaga agaaatccat
    10861 attcagttat cttatttgat gagatagaaa aagctcatcc agatgtattt aatattctgt
    10921 tacaaattct agatgatggt agactaactg attcaaaagg aagaactgta gattttaaga
    10981 atactattgt aataatgaca tcaaatgttg gagcatctac aattggtaga caaaaaactt
    11041 taggatttag tatagctaaa ggagacgaag aagaaaaatc tcaatatgaa aaaatgaaag
    11101 aaaatataat gggtgaatta aaacaaagat tcagaccaga gtttttaaac agaatagatg
    11161 atataattgt tttccactca ctaaatgaaa atcatatatc aaaaatagta cttttaatgg
    11221 cagcgaaact acaagagaga ttaaaagaaa tggatataaa attagaaatg agtgatgagg
    11281 ctgttaaatt aatttctaaa tctggatttg acttagaata tggagcaaga cctcttaaaa
    11341 gagctttaca aaaagagttg gaagatgagc tatctgaagc aatcttaaaa ggtaatgtga
    11401 aaaagggaag taatgtagta gcaaaagtca aagatgaaaa aatagttttt gaaactaaat
    11461 aatttaatag agttgcattt taaaatattg caaatataag ttttataatc taaacaaaat
    11521 tttaagggca atgaatctat aataattcat tgtccttaat tattttattt aatctttaca
    11581 tattgtcttt cagatatgct aaaattatag tatagaataa aaaattaagg atgataaaag
    11641 tatggcaaaa ataaaaacaa aatatgtatg tcaatcttgc ggatatgaaa cagctaaatg
    11701 gcttggtaaa tgtccagaat gtacaaaatg gaatacattt gtagaagaaa tagaccaaaa
    11761 aagcaccaaa aaagaggtct ttataataga taaatcttca tctaaaccag tcagtataaa
    11821 ctcaatagag agtaaagaag aagagcggtt tacaacagat ataaatgaat tagatagagt
    11881 gcttggagga ggtatagtta aaggctcttt agtgcttgtt ggtggtgacc ctggtatagg
    11941 taaatcaaca cttttaatcc aagtatctag taatgttgcc aatttaggaa aaactgtttt
    12001 atatataact ggagaagaat cagaatctca aataaaaatg agagctaaaa gattaggtat
    12061 taactcagaa aatttatata tatttgctga aaataattta agtataattg aatcttattt
    12121 agaaagtgta aatccagaat taataattct agactcaatt caaactgtct tcagtccaga
    12181 aatatcctcg gcaccaggaa ctgtcagcca aattaaagaa ggtacttcaa aattcatgaa
    12241 aatttctaaa aaaatgggaa tttcaacgtt catagttggg catgttacaa aagaaggttc
    12301 actagcagga ccaaaattat tagagcatat ggttgatact gttctatatt ttgaaggaga
    12361 aagatataat acttatagat tagtaagagc tgttaaaaat cgatttggtt caactaatga
    12421 acttggagtg tttgaaatga gggatttagg attagtagaa cttgataatc catctaaaat
    12481 tttaatctct gaaaaaccaa aagatgtagc aggttcagta ataatatcta ctgtagaagg
    12541 tacgagacca atgttacttg aattgcaagc attagtttct cctacaagtt ttggtatacc
    12601 aaaaagaaca tctacaggag tcgattacaa tagagtaggt atgttattag cagtattaga
    12661 aaaacgtgtt ggtttgcaaa tacaaaatca agatgtctat ataaacatag ttggaggaat
    12721 aaagataaat gaaccctcaa ttgatttagg gatagccatt tctgtagcat ctagttttag
    12781 aaatataccg atagatgaag atatagctgt tacaggagaa gtgggactta caggagaagt
    12841 tagagcagta agctttatag aaaagagaat agctgagtgt aaaaaacttg gatttaaaaa
    12901 gatagtagtt cctagaagta attatgatgt tgtaaaagag accaaaggca tagaaatatg
    12961 gccagtagat aacttaagac aagctataaa tatagtactt gggaggaatc aataaatatg
    13021 gagaattttc tagataataa aaatatgcta tatgcattaa aaatgatatc tcctggaact
    13081 ccacttagat taggtctaaa caatgtacta agagctaaga ctggtggatt aattgtaatt
    13141 gcaacaaacg aagatgtaat gaaaatagta gatggaggat ttgctataaa tgcagaatat
    13201 tcaccatcat atctatatga attagctaaa atggatggag ctatagtttt aagtggtgat
    13261 gtaaagaaaa tattatttgc taatgcacaa cttatacctg actattttat agaaacatca
    13321 gagacaggaa caagacatag aacagcagaa agagtagcaa aacaaactgg tgctatagtc
    13381 ataggaattt cacaaagaag aaatgttata acagtttata gaggaaatga gaagtatgta
    13441 gtcgaagata tatctaagat atttactaag gcaaatcagg ctatacaaac tctggaaaaa
    13501 tataagacag tattggacca agctgtaaca aatttaaatg ccttagagtt taatgatttg
    13561 gtaactattt atgatgttgc attagtcatg caaaagatgg aaatggtaat gagagttaca
    13621 agtataattg aaaaatatgt gatagaattg ggtgatgaag gaactttagt aagtatgcaa
    13681 ttagaagaat taatgggtac aaccagaata gaccagaaat taatattcaa agattataat
    13741 aaagaaaaca cagaaataaa agaacttatg aaaaaggtca aaaatttaaa ttcagaagaa
    13801 ctaatagaat tggtcaatat ggcaaaacta ttagggtata gtggtttttc agaaagtatg
    13861 gatatgccta taaaaacaag aggttatagg attcttagca aaatacatag actaccaaca
    13921 gcaataatag aaaacttagt aaattatttt gaaaactttc aacaaatttt agatgcatct
    13981 attgaagaat tagatgaggt tgaaggaata ggtgaaataa gagcaacata tataaaaaat
    14041 ggactcataa aaatgaaaca attagtctta ttagatagac acatatgatg aattttaaat
    14101 gaattttact acttttttct tgaatataat atacactttg gtctataata gataagtata
    14161 actagggggt gaagcattga taaggaaagt aacaagaata ttgtttattt tacttggatt
    14221 tacaataggt ataacaacct atttaacatt aatgaaagat tttgaaatat taacatttgg
    14281 aaaagaaaca tatggttata tcgcagctgt agtagcaggt ataataatag ccattttagg
    14341 atatcttata gaaccatggg ttgtaaataa agtaaaagaa attgctaaaa tagtggataa
    14401 agaattgtca aaatatcctc agactgatat attgttaggg tctatgggtc ttatagtagg
    14461 atttgttatt gcgtatttat taagtggatt agtaaataga ataccaatag taggtggaat
    14521 actatcctta ctattatatt tattcctagg atatcttgga atgaaagttg cgcttaaaag
    14581 taaaaatgat ttatttaata ttggaaaact aggaagatta gcaaatccta ttaaggataa
    14641 agataaggat aaagaaaata aaaaagaagt aaaagccatt cctccaaaag tattggatac
    14701 aagtgtaata attgatggaa gaatagctga tatttgtaag actgggttta tagaaggaaa
    14761 acttattatt cctgcttttg ttttggagga actaagacat attgcagatt cttcagatga
    14821 tttaaaaaga gtaagaggta gaagaggtct ggatatatta aatataattc agaaagaatt
    14881 aaatatagaa gttgaaataa gtgagagaga ctttgatgat atagcagaag ttgatagtaa
    14941 attattaaag cttgctcagg ttttaaatgg aaaagttgtt acaaatgatt ataacttaaa
    15001 taaagttgct caattccaag gtgttgaagt attaaatata aatgagttag ctaatgctat
    15061 aaaaccagtt gctataccag gtgaagatat ggttgttcaa gtggttaaag aaggaaaaga
    15121 ggctcaacaa ggtgttgcat atctagatga tggaactatg atagttgttg atggaggaag
    15181 aaaatatatg aatgagacta taaaagtact cgttacttct gttcttcaaa ctcctgcagg
    15241 tagaatgata tttgcaaaac ctaaaaatta atatgttcaa agaaacctat aatttgggct
    15301 gtttatttta aatagatggt ccaaatttat ttatttataa cgataatgtt taatgtattc
    15361 ttaaagatgg ggatttaaat cagaaagcag ggagaattta tgagaaaaaa gattatatct
    15421 ttcttagcaa catttatcat aatattaaca tcagcaagtc agtatagttt tgcagatgat
    15481 atatcaacac gtggaaaagt aatatttata gatatgaata gaactagtat gagtaatatg
    15541 ttaagaataa aatcattaag agaagaacta gacaatagag ggtatattgg cttgatgaat
    15601 ataagaggcg ataaaggaag tgatgataga aggtcatatg ctagtatggg tgctggtggt
    15661 agagctaatg tggctaatga agaagatatt aattttgaaa gctcgagtaa ggatagaaat
    15721 atagtttttg aatcagctac aggaaaaagt gcaaaaggta taaataattt aactataaat
    15781 aagtctataa atgaaaattt aaactttgga gagtatggtt ctgtattagg gtcattagga
    15841 caaagtttat ctgataatgg attaaaagca tctgtattgg gtaattcaga tataattgaa
    15901 aatggtcaac ttataaaaaa tagaaactta tgtctaactg caatggatga atatggaaga
    15961 atacctaatg gaaatgtaga tactataaat aaaaaagact tatctatgcc ttatggaata
    16021 tcaactgatt atgataaatt gattgtagag actaaagaag cttacaaaaa taatgatgtg
    16081 atttttgtgg agcttggaga cacatataga ttagatttat ataaaccaaa tttaaatgaa
    16141 aaaacatatg agagtatgaa agataacata gaaaaaaata tagatatata tttaaaaaat
    16201 atattttcta tggttgaaga aaatgacact gtctacatag caagtgcatt tccaagtgat
    16261 ttagattata aaaataaaag aagactttcg ccaataataa aattaaatgg agaagggaaa
    16321 ggtatattat catcttcaac tactagaaga gaaggtattg taacaaattt agatgttggg
    16381 gttgaaatat tagacaactt taatataaaa aatcaaaata tggttggaag aaaatatgaa
    16441 cttattaaca gagatgataa taaagaattt ttgatggatg aatatcaaaa gatagtatct
    16501 atttcaagca taaggtctac aatactgaat ggttttgtaa gtatagtttt cttgtcatgg
    16561 atagttgcta tgattgcaat tttatttaga aagcatatat caaaaaatta taaagaaaca
    16621 acatttttta tattaaagga acttttaaaa ataggaatag taatgccact gtcatttatg
    16681 ataacaccaa taatgaattt caaaacacca ttagcaatat ctttaggaat aattataata
    16741 acacttacta tatatcttat aagtaaagtt ttaataaaga acgatttaaa aaacatgctg
    16801 ttttttactg gattaaccat agtaattatg gttattgatg ctgggtttgg ctcatattta
    16861 atgaaaagca atgttatgag ttatgattgt ataattggag ctagatatta tggagtagga
    16921 aatgagtatc aaggtgtggc aatcggtagt gcaatattta catttgcaat tttacttaca
    16981 tataaaaata taccaaagtg gtctataata gttttttctt tggttatctt aattacaagt
    17041 gcatctccaa ttatgggagc aaatgttgga agtgctattt ctgaatgtgt tgcattttta
    17101 ctatttatac tattgatata taatgtaaag atagatttca aaaaaatcgt attattaggt
    17161 atagcagtag tatttgtatt aggagttttt gtagcaatag atatgatttt gggaagtaat
    17221 tcacatttag gtatgtttgt aaaagaaatt tactttaatg gaccaggaga aataatacaa
    17281 acatttagta gaaagataga gatgaattta aagctagctc aaaccagtgc atgggtaaat
    17341 atactgttaa ctggaatagg tgtaatttta gttcttatga ttaatcagat tagatacttt
    17401 aagcaactga tggatgagta tccaattgta tttaaaggat ttatagcatc aatagcagga
    17461 tgtttagtaa ctcttttagt gaatgactct gggattgtgt catcagctac agcctttatt
    17521 tatgtaattg tacctatgat aacattaagt ataaatctta cagcattaaa agaataagta
    17581 ctgtatgaat aatatgtaaa tattaataca ttaatttaac ttctttattt acaaaataaa
    17641 gaagaaagtt tataaaaaat aaattataat aaaaaagagt ttatctcaaa attgattatt
    17701 ctaatcaaat tttaagataa acttttttta ttataaagat aaataacata taacctcata
    17761 ttttaggtag atttttttct tatatgttta ggagtgcatt taaatttttc cttaaaaatt
    17821 ctgtaaaata attttgtatt agtaaatcca tgagcttcta atatactgca taaggtatca
    17881 tttgtgttaa ttaaatcttt ataaatatga gaaatacgca catcatttaa atactctaag
    17941 taagtttgtc ccatatactg tttaaatttt ctacaaaaat attctggttg taagtgtgct
    18001 accttagcga ttttgttaat agaaataggc attttgtaat taatctttgt atattctaaa
    18061 actggttcaa attttgacaa atcaagtact gtttttttca tatttttatt acctacagat
    18121 attttaaagt ttgtatataa ttcaaataaa agttcaaata ataagcttgt aaagagcaga
    18181 ttagctgcag gaggagaact aagtttaatt tctctcatgt tttctaatat aagtttaact
    18241 ttacttgaat tttttttata gttattgtca ttggcattaa ccttaaagtc aaaatagcaa
    18301 tttttaaaat cagggatata tttgtttaga aaagacaatg gtacttgcaa taatatagag
    18361 gtattttgat aaatacatct agttgagtga ataattccag aattaatgaa catacactca
    18421 ttagctttta aattataagt gtaaccctcc atgttaattt gtaaatcacc agaagttata
    18481 taaattattt ctaatgagtt atgccaatga tttgctacat aactaccact atcatcaaat
    18541 agtttgaaat taacatctaa attatcaata ggttcaatta tttcatgtga aaaattattt
    18601 ctgttcataa taatatcctc cttataattt taaattataa atagtaaatt tataatgttc
    18661 aatattaaaa agataatata gactaataaa ttagataata aacatactta agaaaacgga
    18721 taaaatcaaa tataataact gtatattaaa ataacttaaa aaaattattt tattataagt
    18781 gcaaaatata cctatttaaa taagataaga ggggaggatt ttatgtgtat ataaaaggtg
    18841 taaatttagg aggttggtta gttttagaaa aatggatgac ctcaagttta tttgaaggca
    18901 cagaagctga agatgaatac tatttaccaa gacagctttc aagagaggca tatgaatcta
    18961 gaattaagac tcatcgtagt gaatacatca cagagagaga ttttgcaacg attaaatcta
    19021 tgggatttaa ttcagttcgt ataccagtac catactttat ttttggagat tgtgaaccat
    19081 tcataggatg tgttaaagaa cttgataaag catttgcttg ggcagataag tatgggctta
    19141 gtatattgat agacttacat acagttccag gaagccaaaa tggatttgat aatggaggaa
    19201 tatcaggtat atgtagctgg tcacaaaatc cagaatatgt agcgtttaca ttaaatgtat
    19261 tagaaagact tgcaaaacgt tatgggatga ggcatgaatt gtatggaatc caaattttaa
    19321 atgagcctat aacagaaaga atgtggaaca taatgaatgt tccaaatcgg tttaaggctg
    19381 tagataagga gatggcaagg gggagtaaac ctaattcatt agagttttta cgtgattttt
    19441 atataaaagc atataaggta atgcgtcctt atatgagaga ggaaaacgtt atagtatttc
    19501 atgatgcatt tgaattaaaa gcatggaaag actttatgag agaggaagaa tttaaaaatg
    19561 ttgttctaga tacacaccaa tatttgatgt tagctgaagc agatggatgt gaacaaagta
    19621 ttgatagcta tctcaaatat attagagaaa attatgctaa agatatttta caaatgcaaa
    19681 aatattttcc tgttatatgt ggggagtgga gcttatttaa ttcatatgct tgtggtatag
    19741 atacaaatgg aggtcaatca cctctaaatg ggattgaatc aaatatagat aaattatcaa
    19801 aagacgataa aagagaatta tataggaaga tagcaaaagc acagcttgat gcatggagaa
    19861 atggaagtgg tcactactat tggaattata agttattact agatacagtt aatgaagaag
    19921 gttggatagg atgggatagt tgggacctag gcaaatgtgt agctcaagaa tggtatccta
    19981 tagaatatta aactaaaatt ggaggaaaag atatgattaa aaaccctata cttccaggtt
    20041 ttaatccaga tccttgtatt tgtagaaagg gagatgatta ttatcttgta gtttcatctt
    20101 ttgaatggtt tccaggtata cctgtttatc actctaaaga cttaaaaaat tgggagttat
    20161 atactcatat tttgacagat gaaacaaaaa tagatttgaa gaagcttcct tcatctaaag
    20221 gaatttgggc accttgtttg acttattgtg aagaagaaga tttattttac atagtttatg
    20281 gaattatgaa ctctatgaat gcaagatatt ttgatgttga taattattta attacatcaa
    20341 aagatataaa gggagagtgg agtgaaccag tatatctaca ctcatcaggt tttgatgcgt
    20401 ctatttttca tgatgatgat ggtaaaaagt ggattgcatc attagactgg gagactagag
    20461 aaggatatga aaaacctggt gttatatgtt tagtggaata ctgtacaaaa aagaaagaaa
    20521 tagtaggata tccaaagaga atatggtcag ggggaactga tagaggttgt attgaagcac
    20581 cacatataac aaagcgtgga gattactatt atataatgtg tgcagaaggt ggaactggat
    20641 atggtcatag tgtaactatg ggaagggcta aaaatatatg gggaccttat gaaaaagatt
    20701 caatgaatcc aattgtaact tcaattccag gcgattttta tgaaagacat gaccctgacc
    20761 atctaaagcc taaatactat aatccagaat caaaacttca aaaatctggt catggaagct
    20821 atatagaaac aacatcaggt gaagtatatt tagttcatct aacatctaga ccatttgtac
    20881 cagagttaag gtgtacttta ggtagagaaa cagctattca aaaaatgaaa tggacaaagg
    20941 ataattggct tcgaatggaa gatgaaagta atttggcaaa agaatacgta tcagaaagta
    21001 aactagaaga acatttagtt tcatctatac caagttttga tgactttgat tcaaatgaat
    21061 taggtttaca gtactatgct cctaggattt caccattatc atttgcagat gttaagtcta
    21121 gaccaggata tgtaaggatt agaggacaag aatcaagaac atcattaaat aaagtgagca
    21181 tattggcaag aaaattaact tcagtatatg caagaataac cactaagatg gagttttacc
    21241 cagaggtaca tcagcatagt gcgggtttga taatgtatta tgataatatg aattatataa
    21301 atttaagaaa gtattatagt gaaacattgg gtcaaagtgc actatcaata atacatcttg
    21361 aaaatggaga gaaaacggaa tttttaaata ctaggatacc aataaaagat ataccaatat
    21421 atcttcgtct gtatgtacaa ggtcgtaagt catattttga atggagttat gatgaaaaaa
    21481 actaccagag aataggaaag gtatttgata caactaagtt ttcagatgag tactgtaaat
    21541 atggagaatt tacaggtacg tttataggat taacttgtgc agatcgtgta aagcataaac
    21601 actatgctga ttttgatttt tttgaatata tagtagatga atcaaaagat gtcgattaat
    21661 aaaatcatta ctaaaatttt cagagcaaag gtaaatctta tgctctgaaa taagaaacat
    21721 tagaaggcaa atcttacaaa aaggagtatg gtattatgaa tacagaagtt aatgttaaag
    21781 caactacgat tagatatgaa aagatttcat tttttgaaag aatttcttat ggttgtgggg
    21841 atttggggtg caatatcata tactcagcta tgtcagcatt tttgctgttt tattatacta
    21901 attatgcaga tgttagtgca gcagctgtag gtagtattat gcttgtatct aggatactgg
    21961 atgggtttag tgacttaaca atgggaatta tagtggatag aactaaatcc aaatacggta
    22021 aggctaggcc ttggattttg agaatggcga ttccttttgc tatagcagca gtattattat
    22081 tttctgttcc atcaaatctt ggtatcactt ctaaattaat ttatattttt attacatata
    22141 acttagtttc tactgttatt tatacagcaa tcaatgtacc ctatgcaact ctaaattcac
    22201 ttataactca aaaccagtat gaaagaggag tattaagtat atttagaatg atattagcca
    22261 cttgtggtac cttactaata aatggactta cactacctct agttgaatac tttggaaata
    22321 atttatcagc atggactaaa acattctttg tatttggaat agcatctata atggtatttt
    22381 ttataacatt tactggaacc aaggaaagag taaaagcagt taagcaagat aggaatgaag
    22441 taataccatt taaaataggt attaaatctt tatttagaaa taagtactgg atacaaataa
    22501 cattatgttt agtttgcata tttattgtat ttgcgataaa tggtggttca tccgtatatt
    22561 atgcaaagtt tattttggga gatgaaaaat tatttggtcc tataaatatg gtttcaaata
    22621 tatcccaaat tatagctatg tttatggttg ctccttttat aaaaaaattt ggaaaaagaa
    22681 atgtattaat agtaggttca ataatattaa tatcgtcaaa tgttatgttt ataatagttg
    22741 gacaaaatca tataggagta atatttgcaa gtgctataaa gggaatagga agtgctggaa
    22801 tagcatcaac aatgtttgct attgtttcag atactattga atatggagaa tggaagactg
    22861 gatatagaac tgaggggctt ataaatagtg catctagttt tgggtttaaa gtgggaaatg
    22921 gattaggttc agcaatatta ggtgcagtat tatcaattgg tggttatgta ggaacatcag
    22981 ctactcaaag tgatttagct atagtatcaa taaaagtatg ttttatatac ctacctatat
    23041 ttataacaat attacaaatt atcataatgt ctttttataa gcttgataaa gaatatagta
    23101 ctatacttga tgaattaaat actaaataat gaaaaagttt cttataaagt cttaagttta
    23161 attaaggtct attgtaaatg ttccctataa aaactattat atatttatga ttattgaaga
    23221 atttttagag aagcgaataa taaaaatata agaagacttt aaatgatgaa atggttggtt
    23281 ttttagaaat gatttaataa gttattgtta tttaaagcat tataagtgga caattaattt
    23341 ttaatttatg gagatgatat ttaacaatta gaagtaatat ataatatgca ctaagaagca
    23401 atttttcaac tatttatgaa ggtggtggta caagaaaagt atcacctttt ttttgttata
    23461 caaaaaaaca gttgactttt tatatgaacc ccttctataa tgttactgaa attaagtaaa
    23521 atgattgaac aaatgtaaag ataattgaaa agcttgattt tggaggaaag caaatgaaaa
    23581 aaattggaga cttaagatta atgatgaagt gttgttcact ttattacgaa gataatttga
    23641 atcaacagga aatagcaaat caattgggaa tatcaagacc aacaatatca agaatattaa
    23701 aagaagcttt tgaacaagga atagtaaaaa tacagatagt tgatgttttg aaaaatgatt
    23761 accaaaaaat agagagaagt ttggagagaa aatataaatt aaaagaagta atagtagtag
    23821 atgataaaca ggatgcacta acacaaaaac aagaactagc aagagctgta tctgaatatt
    23881 taactagagt agtaaaggaa aatgatataa taggtgtttc aataggaaca acactaaaag
    23941 aaataccaag atatgtggaa aaaagtaact gtaaaaatgt tacatttata cctctattag
    24001 gagggattgg agacaatgaa atagatattc atgcaaatca aatagcagta agtttagcga
    24061 gggcttttgg aggtgatttt aaattattac atgctccagc tgttatgtct gacttgtcta
    24121 caaaagagaa actttgcaaa gacgaaaaaa ttaaagaagt actagattta atagataaaa
    24181 caactatagc aattgtgggt ataggaaatc ctatgagttt aaactcaaca ataatggctt
    24241 ctggatacat gaatgaagca gatatagaag atttaaaaaa atacaactca ataggtgcaa
    24301 tttgtttaca agcctttgat aaagaaggaa aaacttctat acttgaattt aatcaaagag
    24361 tattaggagt gaaactggaa gatttaaaaa agataaaaag aacaataggt gtcgcttcag
    24421 gagatgaaaa aatagaggca ataaaggcat cattaaaagc gaaatttata aatagtttag
    24481 caattaatca cagtttagca cttaaattat tagaagattg tgactaatag aaagatagat
    24541 aaaagttaac aggagggaat gtatatgtca atatcaaaag aaacattgct tgaaatgtat
    24601 aagagaatga atcaggctag aaaatttgaa gagaaagtta gttggttttt tgcaagaggt
    24661 atggttcatg gaacaactca cttatctgta ggtcaagaag cgtcaagtgt ggcggctgta
    24721 atggctttag aaaaaggaga tttagtatca ttaactcata gaggacatag tcaatttata
    24781 ggaatgggaa tagacctaaa taaaatgatg gctgaactta tgggtaaaga aactggattt
    24841 tgtaagggaa aaggaggctc aatgcatata gcagatattg agtcaggtaa cttaggagca
    24901 aatggagttg taggtggagg tcttacaata gctccaggag ctgcacttac acaacagtat
    24961 aaaaaaacag gcaaaatagt tttatgtagt tttggtgatg gagcatcaaa tgaaggtact
    25021 tttcatgaag gaataaattt atcttcaata tggaaattgc caataatatt ttactgtgag
    25081 aataatttat acggtatgtc aacaagcata aaacgtcata tgaatataga aagtattgcc
    25141 actagagcag cttcttatgg aatagaagga atatcaatag atggatataa cccaatagaa
    25201 gtatacgaaa cagtacaaaa agctgctgag aagtgtagaa gaggagaagg acctgtatta
    25261 attgaaagta gaacttatag atggttaggt cattcaaaat cagatgcaaa tgtatataga
    25321 acaaaagaag aaatagaatc atggaaagca aaagacccta ttgaattttt aaaaaattat
    25381 cttatagaaa ataatctatc taatgaagat gaattagata agattcaaga atttgcaaag
    25441 caatcaatag aagatgcagt agagtttgct caaaatagcc caaatccaaa aatagagtct
    25501 ttattagagg atgtatatgc agactaagaa tggtaaagga ggaaaataaa aatgagtaca
    25561 agggaattaa catatgcaca agcaataaag gaagcaatgt cagaagaaat gagaagagat
    25621 gaaaatgtaa tatttatggg agaagatata ggaatatatg gaggagcatt tggtgtatca
    25681 gttggtatga tagatgaatt tggaccagaa agagtaaggg atactcctat atcagaagca
    25741 gctatagcag gagcggcagc aggtgcagca gcaactggtt taagacctat tatggaagta
    25801 atgtttatgg actttgtaac aatttctatg gatgcaattg taaatcaagc ggcaaaaatg
    25861 agatatatgt ttggaggaaa agcacaagtt ccaatggttg ttagatgtcc aggaggttct
    25921 ggaactggtt cagcagagca acattcacaa agtttagaag cttggttttg tcatgtacca
    25981 ggagtaaaag tagttgcacc ttctacacca gcagatgcta agggattgtt gaaagcagct
    26041 ataagagata ataatccagt catatttgtt gagaataaat tgttatacag aaaaaaaggt
    26101 tttgtgccag aagatgatta tgtaattgaa attggaaagg cagatattaa aagagagggt
    26161 actgatgtta cagtaattac ttatggaaga atgttacaaa gtgttgaaga agcagcagag
    26221 actctatcaa aagaaaatat aaatgttgaa attatagatt taagaacttt atatccatta
    26281 gataaagaga ctatagtaaa gagtgtatgt aaaactggga gagttttaat ttgccatgaa
    26341 gcagctaaga ctggtgggct aggtggagaa atatcagccc tgataacaga aagtgaatca
    26401 tttgattatt tagatgctcc agtaaaaaga atttgtggaa aagatgtgcc aataccatat
    26461 aatccagagt tagaaaaagc agttgtccca agagttgatg aaatagaaga agcaataaaa
    26521 tctttaattg ttagataagg agggatagat atggtggcaa ataaaataaa agccacacca
    26581 gcagctagaa gtcaggcaag aaaagacaat ataaaattag ataggctgat tggaagtgga
    26641 gaaaatggaa ggattcattt agtagatgtg ttaaattatt taaaagataa taaagcaaat
    26701 actactcctt tagctagaag aatagcagaa gatttaaata tagatttaga aactattgta
    26761 ggtactggat ataatggaaa gataagaaag tgtgatgtgg aaaaattaac tggaaaagaa
    26821 actattgtat caactaatac atctaaatct agtgagaaaa aagagctgaa aattgaaaat
    26881 gaaaattcaa gaatgtttaa cacagtagaa ggaatatttg aaaagccaaa tccaatgaga
    26941 gctactgtag caaaacgaat gtcagaaagt tattttagtg ctcctgtatt tacattcaat
    27001 atagaagtag atgctacaga attgaaggta cttagagcaa agttaatcga cacagtaaaa
    27061 gaatcaactg gagtaaaatt aactatgaca gatttaatag taatggcagt atctaaaata
    27121 cttccaaatc atcaagcctt aaattcagca tggacagatg agggtatatt tagatataaa
    27181 gatgtaaata tagctattgc agttggttta gatgaaggct tatatgttcc ggtagtaaaa
    27241 aatgcaaaca aaaagtcttt aaaagaaata gcaaaagaaa gcaaagaact tgcggaaaaa
    27301 gtaaagacag ggaaacttat gccagcagac caagaaggta atacatttac aataagtaat
    27361 gttggaatgt atggtataac tacatttaca cctataataa atatgccttc aagtgcaatc
    27421 ttaggggtag gtgctacaca agataagttt gttccagtaa atggagaggc taaaataaaa
    27481 cctataatga acttatcatt aacatcagac catagagtaa tagatggaac agtagctgca
    27541 aaattcttaa aagatttaaa agaattgtta gaaaatcctt tatcaatgct tgtataggtt
    27601 ttgatatttt gttactgata taaatagttt gaatagatta tattattata attgtttcag
    27661 taaatttaaa gcttttatat attaagaatt atttttaaca gtaactatat gtgaatatga
    27721 tttgcttaat taaaatataa gaaaataaat aggaggagag cctatgtcag tagaagtaat
    27781 aatgccaaaa gcaggagtag ccatggaaga aggtactata gtatcttggc taaagcaaga
    27841 aggcgaagaa gtaaagattg gagaacctat actagaaata acaacagata aagttaatat
    27901 ggagatagag tcagaaggag aaggtacact tgctgtaatc atacataaag aggaaggtga
    27961 agtattacca gtatttacag taataggtgt aatagcagaa aaaggggaaa atcaagagga
    28021 agtaaaagct aaatatttat ctggaaatgt ttcaaaagaa gatacagtta aagagaatca
    28081 aaatatagaa gttaaagaag aaaaaataaa caaaaaagag tgtaatcatg attatgatgt
    28141 agtggtaata ggaggaggac ctgggggata tttatcagca ttaaaagcag ctcttttagg
    28201 tggaagagtt gctttagttg aagaaaatat actaggaggt acttgcttaa atagaggttg
    28261 tatccctaca aagacttata taaaaacagc agaaatatta gaagaaattg accaattatc
    28321 aaagagaggt gtaaaagtaa ctgtagataa agaacaggac attaagaagg ccataaaata
    28381 taaaaataga gtagttaaaa aacttacagc tggtgttggc ggattattaa aaagtagaga
    28441 tgtagatgtg tttaatctta aagctagtgt taaagaagag cataaagtaa ttttatcaga
    28501 tggaaaagtt ttagatacag aaaatataat aattgctaca ggttccaaag taaggatatt
    28561 acctataaaa ggaatagaat caaatttaat aataactagt acagaagcat tagatttgga
    28621 aacagtgcca gaaaaattag taataattgg tggtggagtg attggttgtg aatttgcaga
    28681 gatattcaat tcaagaggtt ctaaagtaac tatagtagaa atggaagata gagtaatccc
    28741 aagaatggat aaagagttaa gcgaatcttt aaaatattct cttagtaaaa aaggtataaa
    28801 tgtattaact aaaaagaaag tttctgaatt taaagaagaa ggaaataaca tattagtgtg
    28861 cattgaaggt gaagagccaa taaaagcaga tttatgtcta tatgctatag gaagagaagc
    28921 taatctttct ggcatagagg acttagatat taaaatagat aaaggttcaa tagttgtaaa
    28981 tagtaaaatg gaaacaagta taccaagcat atatgcagta ggtgatgtta ctggaggtgt
    29041 aatgttagct catgctgctt ttaaaatggg agaggtagca gcttcaaatg ctctaggtgt
    29101 gaataaagaa gttgacttag gtgcattacc tagttgtgtt tatacaattc cagaagtagc
    29161 atcagttggt attacagaag aggatgctag aaaaaaatat aatgtaaaag ttggtaagtt
    29221 taattttgct ggaaatggaa gagctttagc ttctggtcaa gaacaaggat atgtaaaagt
    29281 agtagcagat gctaaatatg gagaaatttt aggtatacat atgtttggat gtggtgtagc
    29341 agaacttata aatcatgcag catcatttaa agcgttagag atacctactg atgaagcaag
    29401 tgagttgata tttggtcatc catgtacttc agaagcttta atggaagctt tggcagatgt
    29461 aaatggagaa tgtttacact tacctaaaaa ataaatctaa acataaatta ttaatttaag
    29521 tctattatta atattaattt atatcataaa attttaaaac acttacttag ccatacccct
    29581 tattatgcaa ataatttatt tgcataataa ggggtatttt ttatggaaaa atatagaata
    29641 tagaatcctt gtagtttttg ttgtacaaaa aagatagtaa tataaaataa cattatcatt
    29701 ttagaatgat ttcaattgta attaggaaaa gtgatttttt tgtttttaaa aaaagtatta
    29761 tttgtaaaat ataaaaaaaa ttttcttaat atttgaataa aagaatagct taatttaaat
    29821 gttattactt tataaaaaaa taataagtac aaaaaaaaca atatatggca tataagttgc
    29881 tatataaata ataaggaggg aacaattata aatgaggcaa agaataaaaa acttaattga
    29941 aaatgaagat aagaaaaatc ctttaacaga tgaagcgatt tcaagtaggt taaatattcg
    30001 aagagaagat gttacctttt tgagaaatga gttaaaaata gaagattcaa gacaaagaag
    30061 aaaagttgtt ttaattaaag ctataaaaga tattttaaaa gaagaaaaaa ctataaataa
    30121 aaatgatata acaagaagat taaacagcat tgggtttaca gtatcaagat ttacagtcat
    30181 acaatactta aaagagattc aagattctgg tgacctaaaa cttgataaag agagtgatga
    30241 taaaaaagaa gaaataatca ataatagaga aaataaagat atagcatttg ataaactcat
    30301 aggtagtagt ggtagcttaa gtacaattat aaaactagcc aaagcagcaa ttctttatcc
    30361 acctcatggt cttcatacta ttattatggg gccaactggt gttggaaaga gtgagttagc
    30421 agagtgtatg tataaatttg cagtagaatc atccagattc cctaagaatg caccatttat
    30481 agtttttaat gcagcagatt attcagagaa tccacagctt ttgctatcac agttatttgg
    30541 acacgttaaa ggtgctttta caggagctga tgagaacaaa gaaggattag tatcaaaggc
    30601 agatggagga atattgttta tagatgaaat acatagatta cctcatgaag gtcaagaaat
    30661 actatttcaa ctgattgata aaggtatggt cagaaagtta ggagaaacaa gactaacaca
    30721 taaaatagat gtaatgatta tttcagcaac ttctgagcca atagattctc atttacttaa
    30781 tacatttaaa agacgtatac ctgtaacaat tgaaatacca gaattagttg caagaccatt
    30841 aaatgagagg tttgacatta taaataattt cttcttaata gaagctcaaa gaatgggagc
    30901 aaacatacat ataaagtcag atgtattaaa agctcttatg ctttacgatt gtataggtaa
    30961 tgtaggtcaa cttagaagtg atattcaagt agcttgtgct aggggactat taaaccaact
    31021 tacaaacaaa ctaaaagaag taaatataag catatcagat gtacctggat atgtaaaaca
    31081 aggtcttata aaaatcagaa attgtagagg aaaaatagaa aattatgtag atggggattt
    31141 aattatagac tcaaatcttc aaggtgagat agaaaagaaa aatgaagata tatatacttt
    31201 tccagatgaa atatacaaac ttactgaaag aagacatatt gatttattgg aacaaggttt
    31261 agattttgat gttataaata gaatcattgg aggagaatta gaaagttgca ttcaaaaata
    31321 cataaaacaa gttaaaaaag tttctattag taacaatctt ccagatataa gtccaattgt
    31381 tggaaaatat atcgtagagc taacttatga agtaatcaaa atagcatcac aatacctaag
    31441 ttcactagaa ccgaatctac atttatgttt agcagttcac ctaaaagcag cttttgagag
    31501 attaaaagaa ggaaaagtaa tatcaaatgc tcatttgaaa gaaataatag gaaattatcc
    31561 actagaatat tctgtagcag aaaaggtagc tcaatattta aaggaaagat ataacataaa
    31621 cttaccaaaa gaagaaatag gtataatagc aatatatttt aaaatgagta gtagaagaga
    31681 tatgtctgaa caaaaaaaga taggtgtact tcttatggct cacggaagag tagcatcttc
    31741 tgtatgtgag gttacaaata aactattagg aattaatcac gcaaggtatt tagatatgcc
    31801 atttgagaag aaaccggaag aaatgattga agaagctact acaataataa aagatattga
    31861 tgaaggtaga ggtgtgatta tattagtaga tatgggttca ctttcatatt ttggagatat
    31921 tatttctgga aagactggaa ttaatataag gacaatatct agatttgata cattgctttc
    31981 tatagaggtt atacgaagag cagttttacc agatttaaca atagacgaga tagttgatga
    32041 agttaaaggt atagagccac aagtaaaaga aaaggttagt aaatgtaata atacaaaagt
    32101 agattttaga aaacctataa ttttaacatt atgtattact ggattagggg gagcttgtaa
    32161 gataaaaaaa atcctagagg aaaatattaa aagtataact gaaaaggttg atatagaacc
    32221 tataggtatg attgaatatc caagtcttga tttagagata aaacaaataa gcaatgataa
    32281 aaatgtaatc gccatagttg gaacaattga ccctcagata gcaaatatcc ctttttttag
    32341 tctagtagac ataaatgata aagcaaagtt aaatcaaata aataacctaa ttgatacaaa
    32401 tcaaattggt gaaacaaata aaaaatatga attatcagat ttaatacata aagaagatat
    32461 atttgtggat ttacaggtta aatcaaaaga agaagttcta aaatatatga gtaaaaaact
    32521 tagagagaaa ggttatgtga caaaaaattt ctataaaaaa gtagtggaaa gagataactt
    32581 atttccaact gaattatcag atgaaatagc aatacctcac acagatggaa tagatgtaat
    32641 taggccagct ataagtatag ccatcttaaa gaagcctatt gtgtggagta aaagtaaagt
    32701 aaaaataata cttttattag ctgtagacca aaagtgtttt aatccattaa gcactctact
    32761 ctcatttata gaaacagatg aatttaagaa gataaaaaac attaaagata gagattttat
    32821 tagggagatg atattagatg gagtcaatga aaataattag tagcaattta atttttaaaa
    32881 atattgaagt gtctaacaat gaagatgcat taaagttttt gggacaacgt ttgtttgacg
    32941 aacagtatgt aaaagaaagc tacatacaag ctgttgtagc aagagaaaaa aagtatgcta
    33001 cagggttacc aacagaaata tacggagtgg caataccaca tacagatata gtacatgtaa
    33061 atgagccagg aatagcaatt ggaatactga ataaacctgt aaaatttata atgatgggta
    33121 cagacgatac tgaaattgat gtaaaagttg tatttatgtt agcagtgaaa gagccacaag
    33181 aacaattgca actattagaa aaacttatga ctatatttca agataagaat atactaaata
    33241 atattgttga cttaagtgaa gaaagtgtga gtgatttatt aaactctaaa ttgaaaaatt
    33301 aaacatgtaa agtatattaa aaatgtaaaa ttaaacatgc aaagtatgtt aaaaaatata
    33361 aaaagattat taaagatttc taactataga tatctttaaa ataaaataat ttcaatgggg
    33421 gtgactaatg tggctaaaaa gatattagtt gcatgtggaa caggagtatg tacttcaaca
    33481 attgctataa acaaattaaa gaaagcactt caagacattg gtaaattgga tatggttaat
    33541 attacacaat gtaaagtagt agaagttgca tcaaaagcac ctgattatga tttaataatt
    33601 tgtactacac aagtatctag tagtataaaa acaccagtga taaatggatt acctttttta
    33661 actggtgtcg gaatggataa attaatcaat gatgtattag aagagttaga attataatta
    33721 aaaaaattaa ggaacatggt ctctaaaatc ataagtttta gagacttaaa attaaataat
    33781 ggagggtctt tatatggaga tattaaattt cattgttggt ctaggtgcac aagtaatgat
    33841 gccaataata atatgtattt ttggtttgat attaggtaca aaactaggaa aatctttaag
    33901 agctggttta actgtgggag ttgggtttat aggtcttaac actattatag ctttgctaac
    33961 agataattta ggtccagcta cacaacaaat ggttaagaat ttagggctaa gtttatcaat
    34021 aatagatgta ggatggccag cagcatcagc tatagctttt gcatcaacag taggggcttt
    34081 aattattcca ataggtcttg tggtaaatat agttatgcta attaccaata ctactcaaac
    34141 tgttgatgta gacatatggg attactggca ttttgctttt acaggagctt tagtggcagg
    34201 ggctactcaa agtgtaatgt ggggagtatt tgcagcagta gcaaatatgg taattgtatt
    34261 ggtaatggca gatttaactg ctccaggtat agaggaatat ttaggtatgc caggtatatc
    34321 tcttcctcat ggatttacac aggcatttgt tccaattgct atagtagtaa ataaattatt
    34381 agacttaata ccaggcataa ataagattga gataaatgct gatacattgc agaaaaaatt
    34441 tggattattt ggagaacctt taataatggg gtctgtaata ggtgtaataa ttggtattgc
    34501 tgcgaaatat gatataaaag gaatattaca attaggtgta actatgggag ctgtattaat
    34561 attaattcca aagatggcag cattattaat ggaaggatta ttaccagtat cagaagctgc
    34621 acaggaattt attgagaaga gatttaaaaa cagaggcaag atttatatag gcttagattc
    34681 agcagtagga ataggtcatc ctgttacatt atcagttgca ctagtgttgg ttcctttgac
    34741 tatacttata gcagctatat tgccaggaaa taaagtttta ccatttgcag atttagcagt
    34801 aattccattt gcacttgtat taatcgtacc aattacaaag ggaaatgtgt ttagaacatt
    34861 aataatagga ataattataa ttacttctgg attattaatc gcaactaact tagctccatt
    34921 atttacccaa atggctttaa atgctagttt taaaatgcct gaaggagcaa ctatgatttc
    34981 aagtatttgt gatggtgcga atccattaag ttgggtattt gtaaaagtta tgaactataa
    35041 agttattgga ggagtagttt ttggagttat agctttagga atggctattt acaataggaa
    35101 tagaataata aatgaaaata aaaagctatc tatagaagaa taaggttaaa acaattttat
    35161 taaggagtgt ataggttatg aaaaaatata aatatgattc taaaagatac ttactcagtg
    35221 ttacaatacc aggatttttt atgattttaa tattgattta tgcactgttt aataactata
    35281 caaattttaa tttgaatata tatagtttgt taataattgt ctgtacttat ggtatattca
    35341 atacttttat atcatcaagt aatcctaaaa aaattattat tgatagcaaa tgtatacatt
    35401 ttacctcatt tatgactaca cataagtatg aaattaaaga tatagaaaag ataagaataa
    35461 gagaatttta taataaaaaa atttatctaa aaattaatga tggaaaactt ttcaaaggta
    35521 ggtattggat aagaacaaat atgtttaata atagtatagc attatatagc tatttcattg
    35581 agttggaaga gtgcttatat ccagattcac taaaatttag aaataaaaaa tttgagaata
    35641 agaacatata aaaataaaaa attgaattga agcctagctt aatctttttt gataagatat
    35701 aagtttgaac tttatactaa atttttagaa ttttcaatca agacaataac ataatagcta
    35761 agcaattaga acacaactaa gatgtataag gcatgtatat gatgaatggg aggatttaat
    35821 taatgttatt agagaaatta agaaaagaag tattacaagc atctttagac cttttaaact
    35881 ataatttagt gacattaaca ggaggaaatg taagtgggag agatgaacaa actggctata
    35941 tagcaatcac cccaagtgga atggattata gaaatcttac accaagtgat attgttatag
    36001 tagatgtaga tggaaatatt atagatggaa aatggaaagc atcagtggat ttatcagacc
    36061 acttgtatat atataagcat agagaagaca taaatagtat aattcataca cattctacat
    36121 actcaagttg ttttgctatt ttaaatgaac ctatagaatg tgcaagtaca actcttgcaa
    36181 atgaagtagg gggttcagta ccagttgcaa aattttcgcc accaacatct aaaaagatgg
    36241 gaaaatgtgt tattgaagca attggtgaca aaagagcatg tcttttagca aatcatggcg
    36301 taattgcagt tggtccatct gtaggacatg ctcttacagc cgctgtaatg ttagaagatt
    36361 cagcaaaagt atattactta gcaaaatcaa ttggcacacc agtgctactg cctgatgaag
    36421 aaattcaaag agcgagagat gtatttttta atgtctatgg tcaggataaa taaattagat
    36481 aaaattttaa aagtaatatg aaaatataga tattcaatga tattaaggag atttataatg
    36541 atataataag tttaatagtt aagaagtaaa atatgaaatg taatagtata taaattcatt
    36601 taagactaaa aagaataaga taaaataaaa aggagtctgt atttctatgt attacttatt
    36661 aaacaaaagc acaaatcctt actttaattt ggcattagaa gaatatctat ttttaaatga
    36721 taaatataat gatgatatta taatcatatg gagaaatgaa gaatccattt ttataggtaa
    36781 aaatcaaaat ccatatcagg aagtatatca tgatgttatt gaaaagggag aaattcctat
    36841 tttaagaaga atatctggag gaggaactgt ttatcatgac ttaggtaata tcaatatgtc
    36901 attcatacaa aaagataggc aacttcatga gatagatttt ttggagcata ctaagtttat
    36961 gcaaaagatg ctttcaacct taggactaga tgtatctata actgaaagaa aagatttatt
    37021 tttaaatggg aaaaaaattt caggctctgc acagtctata aaaagaaaaa attctcttta
    37081 tcatggaact cttctttacg attcagattt aaataaatta actaaatatt taaattcaaa
    37141 taaagcaact gaatcaaatg caactaaatc tgtttcaagt aaagttacaa atattaagtt
    37201 tttactcgaa aaagatataa attacttttt agattattgt gttgaatatt taaaatctaa
    37261 tataaagaat ataaaagaac ttgaattgga tgaagaagat attaaaagtg tatacaatat
    37321 aggagaagat aaatataaaa agatagagtg gacatatggt aaaacgccga aatttcaagt
    37381 agtgctacca tttaataatg aaagtaaaat aaatatacat gttaacagat ggaaagtatc
    37441 aaaatttttt atttcttatg atgataatgt aattaatatg gacaagttgt tagatttgaa
    37501 tttctttaaa gaagaaataa aagagagtat tttagaaaat tatccacatt acatagattt
    37561 aatcaattta atattttaat ataaaacctc taatttgata aaattgtctt atatcaaact
    37621 agaggttttt aatattcttg catattaaca accattacaa aattgtaaaa ttaaaaacaa
    37681 cactattgaa aaatcaatat atattgtaat aaatatatgt gtttttcatt agcaaataga
    37741 cattaactat ttatacaact gaaaatttaa tatataatta atcagatggt taaaataaaa
    37801 atattaaaag ttttaataaa tgatggttaa aaataaaata cgaggtgata ccatgtatag
    37861 tgttataatt gttgcagcgg gaagcggaag gagaatgaac ttagatataa acaaacagtt
    37921 cataaaatta agagaaaaag aaattattgc tcatacaatt caagtttttt atgaaaatat
    37981 aaatatagat gaaatagtgg tatgtataaa aaaagaagaa gaagattttt ttaaagaaaa
    38041 tataataaat aagtataact ttaaaaatat aaaaatagca tatggcggaa aagaaagaca
    38101 ggactcaata tataatggtt taaaaaaatt agataaaaat tgtgatatag tacttatcca
    38161 tgatggagca agaccatttg tcgaccatag aataatcaat gaatctataa aggtagctaa
    38221 agaaaaaaag gctgtggttg taggtgttcc agtaagtgat actataaaga tagtgtcaga
    38281 tggaacagta caagaaactc cagaaagaaa tttgctgtgg gcagcacaaa cccctcaaac
    38341 ctttgaatat aatctcataa tagatgctta tgaacaagca tataagaaca attattatgg
    38401 tactgatgat tcaatgttgg tagaaaatat aggtcaaagt gtcactatgg taatgggttc
    38461 ttatgaaaac ataaaaataa ctagtccaga agatttaaat atagcagaac aaatattaaa
    38521 tatggaaaaa agagatgaag ttaacagtag aaggagaatt atatgagaat aggattagga
    38581 tatgatgtac acaaattaac agaggataga aaacttataa tcggtggtgt agagatacca
    38641 cacgataaag gtttgttggg tcattctgat gctgatgtat tgatacatgc aataatggat
    38701 tctattttag gtgctctagc attaggagat atagggaagc atttcccaga tacagatgaa
    38761 gaatataagg gagcagatag tatgaaatta ttagaacatg tgtataatct aataacaagt
    38821 aaaggatata aaattggtaa tatagacagt actataattg ctcaaagccc taagatggct
    38881 ccatatattg agagtatgag aagtaatata tcaaaagttt taaacacaga cattgataat
    38941 ataaacataa aggcaacaac agaagaaggt cttggtttta caggagcaaa acagggaata
    39001 gcttcacaaa gtatttgttt attattgttg acaagtcaga ataattaata tattattagt
    39061 aataagttta atggatatca agtaataggc ctatatagaa tatctataat gtatgaattt
    39121 aagtgaaatt aatataaata taaaattagc tatgataaag aaatagtaaa atgatgaaat
    39181 cttcacagag agaaaacggt ggtgagagtt ttcaagagga agtctttgaa cctgtctttt
    39241 agcttaaagg tataaaaatc tttacggtag gaaccgttat attcccaaaa gagagctatt
    39301 catatagcta actagagtgg taccgcggaa attaaacctt tcgtctctat acttgtatag
    39361 agatgagagg ttttttatat tttcaggaag ttaatattca ggaggaatct attaatgaaa
    39421 atgtcaaaaa tgtttatgcc gacattaaaa gaaatcccag cagatgctga gattacaagc
    39481 catcaattaa tggttaggtc aggcatgata aaaaaaatga cttcaggtgt ttataaccaa
    39541 ttaccaatgg ggttaagagt gttcaaaaaa attgaacaaa taattagaga agaattaaat
    39601 aaaaaagatt gtcaagaaat actttgtgca gccttacttc cttctgaatt atggaaagag
    39661 tctggaaggt ggactgctat gggtgaagaa atgtttagac taaaagacag aacagaaaga
    39721 gagtactgtc ttgggccaac acatgaagaa gcattcactg atataataag acaagaaatt
    39781 acttcatata aacaattgcc actgaacttg taccaaatac aagtaaaata tagagacgag
    39841 agaagaccaa gatttggtgt tatgagaact aagactttta caatgaagga tgcctatagt
    39901 tttgatgtag atgataaagg tttagataag tcatatcaag atatgtttga tgcatatgta
    39961 agtatatttg atagatgtgg attggagaat agccctgtac aggcagattc aggagctata
    40021 ggaggttcta catcagccga atttatggtt aagtcagaag ttggtgaaga tgaagttgta
    40081 ttttgtagtg gatgtgatta tgcagccaat gtagaaagag cagaatcttg taatctagca
    40141 tcacaaaaag aagaaatgaa agaattagaa gaggttcata caccaggagc agctacaata
    40201 aaagagttag aagaattttt aaaaacttct ccagataagt ttgctaaaac tttagtatat
    40261 gaggcagatg gaaaaacagt tgtagtcgtt gtaagaggag atagagaagt taatgaaatc
    40321 aaagtatcta atgccatagg ttctgttata gaatttgctc ttgctacaga tgatgtagtg
    40381 agaaaagtaa ctaatgcaga agtaggattt gcaggtccaa taggtataaa tgctgactat
    40441 gtatttatag ataaagaaat tgttgaacaa agaaacatag ttgttggggc taataaaact
    40501 gagtaccata taaaaaatgc taactatgga agagattttg aaggaatagt tggagacttt
    40561 agaaatgttc aagaaggcga caagtgtata gtatgtggta agccacttga aatagctaga
    40621 ggtgttgaag taggacatat atttaaacta ggaactaagt actcagaatc tatgaatgca
    40681 aacttcatag acaaagatgg aaaatcaaag cctatagtaa tgggatgtta tggaataggt
    40741 gttgaaagaa cagcagcagc tataattgaa caacataatg atgagaaagg tataatatgg
    40801 cctttgtcag tagctccata ccatgttgtg atagttccag caaatatgaa aaatgaagaa
    40861 caaatatcaa tagctgaaaa tatatataat gatttgcaag ctatgggtgt agaagtttta
    40921 ttagatgaca gagatgaaag aataggtgtc aaattcaatg attcagaatt aataggaata
    40981 cctatgagga ttacagtagg taaaaatatt aatgaaggga aagtagaatt taaacttaga
    41041 cataaagaag ataaagagat aattgacata gaagaaataa atgaaaaagt aaaggcagag
    41101 tttatcagga ataatgttag gttaggataa taacttaaat aagatattgt atagataatc
    41161 aaagttgtac tttatagaca ccattttatc tatatataag gatataaaat ggtgtttttt
    41221 tataaaacaa ataaatgagg aggtaattga aatggcaaaa aatgaaaaac aatttgttga
    41281 agaaataaca aagatggaag atgattttcc acaatggtac acagatgtaa taactaagac
    41341 tgacttagtt gattatgcac cagtaaaagg ttttatggtt gtaaagccat atggatatgc
    41401 attatgggaa aagatgcaag aatttatgga taaaaaattt aaagaaactg gacataaaaa
    41461 ctgttatttt ccattattaa taccagagag tttattaaac aaagaagcag aacacgttga
    41521 aggttttgct ccagaagttg catgggtaac acatggagga aataaaaaat tagaagaaag
    41581 attatgtgta agacctactt cagagactat aatatgtaca atgtatgcga aatggttaaa
    41641 atcatataga gaattaccat atctttataa tcaatggtgc tcagttgtta gatgggaaaa
    41701 atcaactaga cctttcttaa gaacatctga gtttttatgg caagaaggtc atacgttaca
    41761 tgaaacagca gaagaagcac aagaagaaac aatacaacaa ttagaagtat ataaagcgct
    41821 atgtgaagaa ttacttgcaa tgccagttgt agctggtcaa aaaagtgaaa gtgagaaatt
    41881 tgcaggtggt gaaagaacat atactataga agctatgatg catgatggta aagcattaca
    41941 atcaggtaca agtcacttcc taggtcaaca ctttactaag gcttttgata ttacttttgc
    42001 agatagggaa ggaaatttag ctaatccata ccatacatct tggggagcat ctacaagact
    42061 tataggtgga cttataatga ctcatagtga taacagaggt ttagtattac caccaagagt
    42121 agctccaatt caagttgtta tagttcctat agctgctaaa aaaggaaatg taatggagac
    42181 tgttgataaa atatatgctg atttaaaagc taagggagta gctgtagaag ttgatgatag
    42241 agataactat acaactggat ggaaatttaa tgagtgggaa atgaaaggtg ttccagtaag
    42301 agttgaaatt ggaccaaaag atatagaaaa taatcaagct atggtattta gaagagatac
    42361 tttagaaaag gattctatgc ctttagaagg attagctgat gctatatgtg atttatttga
    42421 tgttatacac aatgatatgt ttgaaaaagc aagaaaacat agagaagaca atacatctat
    42481 agttgaaaat atggatgagt ttagaaaagc tttagaagaa aagccaggat tcataaagac
    42541 tatgtggtgt ggagatgcag aatgtgaagc taagattaag gaagaaacag gagcaactat
    42601 aagatgctta ccttttgaac aagaaaactt aggtcacaag tgtgtgtact gtggaaaaga
    42661 agcagatagt atggtagtaa tggcaaaagc ttactaaaat acatttaaat aaaaactggg
    42721 gtagaaagta tttaatactt tatcccagtt ttttgttttt tatgagtaat aaaatgtatt
    42781 tgtaactatg tcataagata agtcatagat acttatatta aaaagaatat aatagagaac
    42841 tatttttaat aattacatat taatgaaagc aaaatatttt gttatataga ttttcaataa
    42901 agcaaacaat aaatataaat gaatattagt aaggagtgct tttaattttt agaaaataaa
    42961 tgacttaaaa gaaagattta tgaaattaaa actaggattt tctgatataa taaacatgtg
    43021 tatttttaaa taaaaaggat attattatta gatttgatta aaaataaact tgcaaaacaa
    43081 tgtactagtt taatattata gttatattga ataaaatatc aggaggaagt aaaaatgaat
    43141 gtaagagtaa ggtttgcacc aagtccaaca ggatttgtac atataggtag tttgagaact
    43201 gctttatata actatttatt tgcaaaaaaa atgggcggag aatatatatt aagagtggaa
    43261 gatacagacc aaagtagatt agtagaaggt gctatagaga atatgcttaa tgctatgaaa
    43321 tgggctggtg tcaaccatag tgaaggtgtt atattagatg atagtggaaa agtagtacaa
    43381 aaaggagaat atggtccata tattcaatct caaagattag atatatacca agaatatata
    43441 aagcaacttt tagatagtgg aaaagcttac tactgtttct gtacaaaaga aagactggat
    43501 gaagtaagag atgctcaaag agcagcagga gaaacagcta aatatgatgg tcattgtaag
    43561 aatctttcta aagaagaagt agaagcgaat ataaaagcag gaataccata tgttataaga
    43621 ttaagattgc cagagaatca tacaattaag tttacagact tagttagagg agatatggaa
    43681 tttaatacta atgacttaga tgaccaagta ttaatgaaaa cagatggatt tccaacttat
    43741 cattttgcag tagttgttga tgactatttg atgaaaatta cacatgttat aagaggagaa
    43801 gaatgggtat catctactcc aaaacatgtt tatttatatg aagcttttgg atgggaagca
    43861 cctgtatttg tgcatttacc aaatatactt aataaagaaa agaaaaaatt aagtaaaaga
    43921 caaggtgatg tagctgttga agactttaag aaaaaaggat atttaccaga gggattagta
    43981 aactatgtag cattagttgg ttggtctcct gaagataatc aagaattgtt tacaatggag
    44041 gaattagaaa aagcgttctc tgtagaaaga gtatctaaaa gtggtggagt atttgatact
    44101 gaaaaattaa attgggttaa tcagcactat ataaaagatg gtgatgatgc ttatctaaca
    44161 gacttagcaa taccattttt aatagaagat ggatttataa cagaagaaga agctactaat
    44221 aaatatgatt tcttaaagag tatgatatca gtacttaaag agaaattaca atatgtaaaa
    44281 gaagttactg aacatgcaag tatatttttt ggagataaaa tagaggtaga aactgaagag
    44341 ggaagagagt tcttaagatt agaacatata cctactttaa tagatgcttt gagagaaaaa
    44401 atagaaaaaa cagaggtatt aaatgctgag tttgttcaag ctatgcttaa agaaatacaa
    44461 aaagagtaca aaataaaagg gaaaaattta tttatgggct caagaataat tttgacaggg
    44521 caaatgcatg gtccagattt accaaaagta atggaagttt taggaaaaga aacttgctta
    44581 aatagaatag cttatgtaaa aaataatata ttatagtcat aaaagtccgc taatttagaa
    44641 gcggactttt tttgtgttag tatttggtga aaatatctgc ttaagaaaat gaaggtattt
    44701 aaggtaataa atttaatata taaaaagcaa agcaaaaata taaataaaat atgaataata
    44761 aactaataaa atattaagca tagaagaagg gaatctatta ttttagtttg atttaattat
    44821 taagggggta attactatgt atagtaatat tgatgatgtt aaaaaggaat taaaggagct
    44881 atgcttagaa tatgttacaa ttttagaaaa attaaaagat gaaaaaatga ttacagaaga
    44941 aacttttgaa aagtgctctt ctcaaaaaaa aatattttta gaagaacaat agaggatggt
    45001 aatagtatta ttattatgta gtttgaaaga tagtacgaaa aatgatagta atactattat
    45061 ttattgcaat tttcaactat aatataatat ataatgttaa gaagataatt tataaaaata
    45121 cagtgaggtg atgagtgtga aagtttataa tacattgact agaacaaaag aagaatttgt
    45181 tccattagaa gaaggaaagg taaaaatgta tgtgtgtggt ccaacagttt ataactatat
    45241 acacataggt aatgcaagac catttataat atttgatact ctaagaaggt atttagagta
    45301 tagaggatat gatgtaactt atgtacaaaa ctttacagat gttgatgata agattataaa
    45361 tagaagtcat gaggagggaa tatctcctga agaagttgcg gctaagtata taaaagaata
    45421 ttttgtagac tgtgatgggc taggaataaa aagagctact gttcatcctc aggttacaga
    45481 taatatacaa cagattatag agtttataaa agagttggaa gataagggat atgcatatgc
    45541 agtaaatggt gatgtatatt ttgatacaaa taagtttgaa ggttatggaa aactttcagg
    45601 tcaaaaacaa gaagatttag aggcaggggc tagaattgag gttaatgacc aaaaaagaca
    45661 tcctatggac tttgttcttt ggaaggcaaa aaaagaaggt gagccaggat gggatagccc
    45721 ttggggagaa ggtagaccag gatggcatat agaatgttct gttatgtcta agagatattt
    45781 aggtgaaaca attgatatac atgcaggtgg gcaagattta acattcccac atcatgaaaa
    45841 tgaaatagct caaagtgaag ctagaagtgg aaaaacattc tcaaaatact ggatgcataa
    45901 tggatatata aatataaatg atgaaaagat gagtaaatca aaaggtaatt tctttacagt
    45961 aagagatata tcaaaattat atgatttaga gatagtaaga tttttcatgt tatcagcaca
    46021 ttatagaaat ccagtaaact ttagtgatga gatgttaaat caagctaaag caggtcttga
    46081 aagactatat aatactaaag aaaaattaga atttacgcta agtaatttag tagaatctcc
    46141 gttaacagaa aaagaagtag agcttgttaa agaattagat gactttagac aaaaattcat
    46201 agatgctatg gatgatgatg ttaatacagc agacgcagta agtgtaatat ttgaattagc
    46261 taagttaata aattctaatg tagatgaaaa ttcttctttg gagtttgcta aaaaatgctt
    46321 agatgaattt aatgaactta caggagtatt aaatattgta aataagaaaa aggatactgt
    46381 attagataaa gacattgaag aattgataca aaaaagaact gatgcaaaga aaaataaaga
    46441 gtttcaatta gctgatgata ttagacaaca attactagat atgggaattg tattagaaga
    46501 cacaagacaa ggtgttaagt ggaaaaggat ataaaaatgg aaaaaactga attagttact
    46561 atgtcaccat tagttttagc atacttaggt gatacagtgt atgagacata tataagagaa
    46621 tatttaatta gacagaatac acaaagaaaa gttaatgatt tgcataaact agctataaag
    46681 tatgtaaaag ctaaagctca ggcaactata attcatgaaa ttgaaattga gttaactgaa
    46741 gaagagagta aaatttataa aaggggaaga aatcaaaagt caaatacttc tcctaagaat
    46801 gcagatatta tagactacaa acatgcaact gggtttgagg cattagttgg atatttgtat
    46861 ttaaataatg aaatagagag acttcaatat attatcaata aaggaatcaa aattattgaa
    46921 agagatatgt aaatattaaa gagtgttgtc ttaataataa gtaataaggc aacacttttt
    46981 ttataactaa tgtataataa atatatagaa attagtaatg agaaaggata aaaagttatg
    47041 aaagtaaaat taatatcaca tacacctgaa ccagaaaaag taatagctat ggcagctaag
    47101 ctatgttatt caccagttgg gacagacgaa atagaaaaag acttaacaga tgaaagtata
    47161 gagaaatttt taaatatgtt attaagtata ggtcatgggt caatattaga acatgcttca
    47221 tttacatttt caatagaagg tatttcaagg gcatgttcac atcaaattgt tagacatcgt
    47281 atagctagtt tttcacaaca aagtcaaaga tatgttaaat tagaacaatt tgagtacata
    47341 attcctccag aaatagaaaa aatagaaaag gcaaaagagt tatttataga ctccatgaaa
    47401 aaagaccaag agaattatga taagttagtt gaaatattgt ttgaaaatca ttataatgac
    47461 ctaataaaaa acggtaaaaa tgagaaaaca gctaaaagac aagctgagaa gaaagcaata
    47521 gaagatgcta gatacgtatt tccaaatgca tgtgaaacaa aaatggtatt tactataaat
    47581 gctagaagtt tgtttaattt ctttgaacat agatgctgtg aaagagcaca gtgggaaata
    47641 agaaatttag ctgtggagat gttaagagag gttaaaaagg ttgctcctat attatttaaa
    47701 aagactggtc caagttgtgt aaatggaagt tgtccagaag gaactatgac ttgtggagat
    47761 atagttcaag ttagagaaaa atttaaggcc ttgtaggagg tgaataattt ggcgagtata
    47821 gaaggaagaa atccggtaat agaagcaata aaaagcgaca gagaaataga taaaatatta
    47881 attgcaaatt cagctaaaga aggttcaatt aagaaaataa taggaatggc taaagataag
    47941 aatataatta ttcagtatgt tgataaacat aagctagatg aagtaagtac aagtcattca
    48001 catcaaggtg taatagctta tgcaagtgag tataagtatt atgaattaga tgagctaata
    48061 gatttagcaa agaataaaga tgaagaccca tttttcatta tattagatga gataacagac
    48121 ccacataatt tgggttcaat aataaggaca gcagatgcag taggagcaca tggagttatc
    48181 attccaaaaa gaaggtctgt acacataact cctgtagttg ccaaagcatc tgctggagca
    48241 gtagaatata tgccagtttg caaggtaacc aatatagtta atacaataaa aagactcaaa
    48301 gaagaagggc tgtggattgc tgcagctgat atggatggag aaacttttta taaacaaaat
    48361 cttactggtc ctcttggtgt agtaattgga agtgaaggtt ttggaatatc tagattggtt
    48421 aaacaaaact gtgactttat agtaaaaatg ccaatgatag gtaatgttac atctttaaat
    48481 gcatctgtag caggtggaat acttttatat gagatattca gacaaagact ggataaaagt
    48541 aaataggcat gaaaaaaaat ataaatcatt acttaataat agatggctac aatattataa
    48601 atgcgtggga caatttgaaa gaactggcta aagaggactt agaagattct cgagaaaagc
    48661 ttattgatga cattatagaa ttttctgagt ttatgggtta taagactata atagtttttg
    48721 atgcttataa tgttaaaaat tctcgagaaa aagttgaaaa aagaaaacac ataacaatag
    48781 tttatacaag agaacaccaa acagcagata gttatataga gaaatttata acttctttat
    48841 caaagtatga tgatgtaaaa gtagccacta atgactatgc agaacagcaa atgattttag
    48901 gaaaaggtgc tactagaatg tctgcaagag aattaaagtt agagttagat cgttccaaga
    48961 ataaaatgaa ggaaaaaaat atcggtttga ggaaaaaaat tcagcgaaat tggttggagg
    49021 aaaggttaga taaagaaaca ttgtcgaaac ttgagaacat tcgtagaaag cgttgaaatt
    49081 actaggttct ttagactata atatacctat aaatttgttt tatatatggg ggagatttac
    49141 atgttggtag caaaagaaaa aagttatgag ttagtggaca attgtcagca ggatgagtat
    49201 aacattgtat taagagcaag tgaaggggat aaaatagcac tagagtacat tattactaaa
    49261 tacagaaatt ttgtaaaggc aaaagcaaag tcatattttt taattggagc agataaagaa
    49321 gatataatac aagaaggaat gataggcctt tataaggcag ttagagattt tgatggaagt
    49381 aagaccaatt catttaaatg ttttgcggag atatgtataa caagacaaat aataactgct
    49441 ataaaaactg caacaagaca aaaacatata cctttaaatt catatgtttc tttgaataaa
    49501 ccaatatatg atgaagagtc agacagaaca cttttagata ttatagctac aagtatagta
    49561 acagatccag aagagcttat aattagtaaa gaagagttaa aaaatataga atcaaaaatg
    49621 aacgaattgt taagtgactt ggaattagaa gtactagaat tatatttaaa tggaaagtca
    49681 taccagttta tagcggacaa gcttaaaaga gatgtaaagt caatagataa cgctttacaa
    49741 agggttaaga gaaaattaga aaaacatctt gaaaacagaa atgattaata gtaaaatact
    49801 taccataagc ttattgtgag caaaattaat ttatatcgaa agataaggga ggaaattcaa
    49861 aatggctaaa gctaaatacg aaagaacaaa acctcatgtt aatataggga caataggaca
    49921 cgtagaccac ggtaaaacta cattaacagc agcaataaca aaaacattat atgacagata
    49981 tcaattagga gaagcagtag atttcgcaaa catagataaa gctccagaag aaagagaaag
    50041 aggaatcaca atatcaacag cacacgttga gtatgaaaca ccaaatagac
//
LOCUS       DAEOTL010000019        49430 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEOTL010000019 DAEOTL010000000
VERSION     DAEOTL010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.019"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..234
                     /locus_tag="KRH82_001428"
     CDS             <1..234
                     /locus_tag="KRH82_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654715.1"
                     /translation="PDVNIDIDGDGKPDVNIDIDGDGKPDINIDTDESLDSNVGQNVQ
                     TGDQSNIMLDLALMFISLFFLIKNLTNKYLRRK"
     gene            996..1958
                     /locus_tag="KRH82_001429"
     CDS             996..1958
                     /locus_tag="KRH82_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBG8654716.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            2037..2666
                     /locus_tag="KRH82_001430"
     CDS             2037..2666
                     /locus_tag="KRH82_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBG8654717.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLRVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            3500..3913
                     /locus_tag="KRH82_001431"
     CDS             3500..3913
                     /locus_tag="KRH82_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654718.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLISVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            3981..4397
                     /locus_tag="KRH82_001432"
     CDS             3981..4397
                     /locus_tag="KRH82_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654719.1"
                     /translation="MSKSETGVRSKLILELIVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            4398..4610
                     /locus_tag="KRH82_001433"
     CDS             4398..4610
                     /locus_tag="KRH82_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654720.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            4996..5166
                     /locus_tag="KRH82_001434"
     CDS             4996..5166
                     /locus_tag="KRH82_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654721.1"
                     /translation="MSALLYGVCNKPISVSIVINMQEFKIGVSMAYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            5709..6587
                     /locus_tag="KRH82_001435"
     CDS             5709..6587
                     /locus_tag="KRH82_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBG8654722.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILKAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVETLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKAAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            6623..8518
                     /locus_tag="KRH82_001436"
     CDS             6623..8518
                     /locus_tag="KRH82_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8654723.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            8787..10694
                     /locus_tag="KRH82_001437"
     CDS             8787..10694
                     /locus_tag="KRH82_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8654724.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQKEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDELMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSQFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            10684..11133
                     /locus_tag="KRH82_001438"
     CDS             10684..11133
                     /locus_tag="KRH82_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8654725.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            11233..12120
                     /locus_tag="KRH82_001439"
     CDS             11233..12120
                     /locus_tag="KRH82_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8654726.1"
                     /translation="MAIYLEMPKLIHEFPFRTLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            12525..13973
                     /locus_tag="KRH82_001440"
     CDS             12525..13973
                     /locus_tag="KRH82_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBG8654727.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIIHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            13999..16389
                     /locus_tag="KRH82_001441"
     CDS             13999..16389
                     /locus_tag="KRH82_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBG8654728.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            16391..17062
                     /gene="pgmB"
                     /locus_tag="KRH82_001442"
     CDS             16391..17062
                     /gene="pgmB"
                     /locus_tag="KRH82_001442"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBG8654729.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKYDHIVEDTSLLNYNTLLQAWSK
                     KINLD"
     gene            17101..18504
                     /locus_tag="KRH82_001443"
     CDS             17101..18504
                     /locus_tag="KRH82_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8654730.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTIIGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKEGIGKLRKCVK"
     gene            19418..20077
                     /locus_tag="KRH82_001444"
     CDS             19418..20077
                     /locus_tag="KRH82_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003410138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654731.1"
                     /translation="MIIEVSNLSKVVDLLNTELTILRNIDLYIEEGEFVSIMGASGSG
                     KSSLISILSGLDKNYTGNVKVCGENLSKLTDDELAEYRNRKIGIVFQSFNLITSMSVE
                     ENIKLPLIFSDNKDYKIVDKMIKKVGLTSKTKNNIKQLSGGEKQRVAISRALVCSPNI
                     LFADEPTGSLDSTNSHAIMKLFKNINNEYGTTIVMVTHDIQMAEYSDRIISIKDGTII
                     K"
     gene            20089..22590
                     /locus_tag="KRH82_001445"
     CDS             20089..22590
                     /locus_tag="KRH82_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654732.1"
                     /translation="MIFHEVYKIYSKNSLKNNKLLKISCIISIVFATAILLFTRVLTD
                     TYSSEVKRNMAITNGGDIKIQNIEYNKYYFTSEQIDKLEELKGKESIDFQLGSSMNTN
                     ILSNGMIESTELTVVNNIKMQNTYLKLRNENDIVLSQKTANKLNVNIGDKVFLKLHSS
                     VYDDTYFKVSDIIPKRFSLSTAQKEAEVGQEVVGESYVYLPNETKYNVAYINIINKEN
                     VKNIKNEIKNVFKNHFEVRTTDELEQSIIKRISMQLDSINLIGAISLLSTGICLCSTF
                     IVFILNRINDFSTFKALGIKKRSLSFLVFTELMSITIKGIIIGIILGIPITIFYINLQ
                     HINLFNISILSIIKNIFISIVIIIIETSIFSLIPISFVKKIHYEGINRDNSMLSSYKF
                     NFIPDIILVIFLTSISFTIYVKSFLGIFFILGLILLDLLVYSLIYALLKMVCLIKKII
                     KGKYSITFIYLNNDCKTNAFSSSLLTITIIFVLLLFMISEITFAMFSNYEVDNSIKNS
                     IVYQTTLEGKLITDKKLIENDIDYFQYYPIKIDSIESVNNISVNDYIEKIPYENRKDV
                     MNDLNDLSVDLFNTKQTILKSDLEYGNWFKENDKENSIIINNYLHRYLIDYKLGDTVK
                     LRINGKKIDFKVIGFLSPKSLNKGVDLGYININENISPKTLDLSKNQPVIYFFKEKLD
                     NTLLSKLLHNDKYANLEDYNDFAYSMKTYVDDQKSLLLNIIFAVSLSSILLILTSQII
                     IFIRRVLDYQIMYRVGMSKRKLIKIGLLEMIIVSIIQSTLIAIFYELFRFLLISLLQR
                     AYNINYLLILIEFLVVLSINCFIFILAQRNIKLDL"
     gene            23104..23946
                     /locus_tag="KRH82_001446"
     CDS             23104..23946
                     /locus_tag="KRH82_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8654733.1"
                     /translation="MIINKILNNNVIITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            24091..26019
                     /locus_tag="KRH82_001447"
     CDS             24091..26019
                     /locus_tag="KRH82_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8654734.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISVGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            26080..27507
                     /gene="ascB"
                     /locus_tag="KRH82_001448"
     CDS             26080..27507
                     /gene="ascB"
                     /locus_tag="KRH82_001448"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBG8654735.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFISA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYIREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            27918..28694
                     /locus_tag="KRH82_001449"
     CDS             27918..28694
                     /locus_tag="KRH82_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8654736.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAIALTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IVKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            28710..29075
                     /locus_tag="KRH82_001450"
     CDS             28710..29075
                     /locus_tag="KRH82_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8654737.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(29242..29991)
                     /locus_tag="KRH82_001451"
     CDS             complement(29242..29991)
                     /locus_tag="KRH82_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBG8654738.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            30469..30894
                     /locus_tag="KRH82_001452"
     CDS             30469..30894
                     /locus_tag="KRH82_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654739.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIG
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            30926..32113
                     /locus_tag="KRH82_001453"
     CDS             30926..32113
                     /locus_tag="KRH82_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBG8654740.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCINAFKDSDVDVIMSVGRSTNIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            32305..32709
                     /locus_tag="KRH82_001454"
     CDS             32305..32709
                     /locus_tag="KRH82_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBG8654741.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNYIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKGDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            33355..34215
                     /locus_tag="KRH82_001455"
     CDS             33355..34215
                     /locus_tag="KRH82_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8654742.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            34205..36076
                     /locus_tag="KRH82_001456"
     CDS             34205..36076
                     /locus_tag="KRH82_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8654743.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            36096..37550
                     /locus_tag="KRH82_001457"
     CDS             36096..37550
                     /locus_tag="KRH82_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBG8654744.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            38575..39783
                     /locus_tag="KRH82_001458"
     CDS             38575..39783
                     /locus_tag="KRH82_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654745.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIIPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            39814..41193
                     /locus_tag="KRH82_001459"
     CDS             39814..41193
                     /locus_tag="KRH82_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8654746.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            41299..42489
                     /locus_tag="KRH82_001460"
     CDS             41299..42489
                     /locus_tag="KRH82_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8654747.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(42617..43945)
                     /locus_tag="KRH82_001461"
     CDS             complement(42617..43945)
                     /locus_tag="KRH82_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654748.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIKIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(44563..45777)
                     /locus_tag="KRH82_001462"
     CDS             complement(44563..45777)
                     /locus_tag="KRH82_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBG8654749.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYEI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASYTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            46203..46919
                     /locus_tag="KRH82_001463"
     CDS             46203..46919
                     /locus_tag="KRH82_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBG8654750.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            47054..47680
                     /locus_tag="KRH82_001464"
     CDS             47054..47680
                     /locus_tag="KRH82_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBG8654751.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(47880..49424)
                     /locus_tag="KRH82_001465"
     CDS             complement(47880..49424)
                     /locus_tag="KRH82_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8654752.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
BASE COUNT        19289 a         5209 c         8251 g        16681 t
ORIGIN      
        1 ccggatgtaa atatagatat agatggagat ggaaagccgg atgtaaatat agatatagat
       61 ggagatggaa aaccggatat aaatatagat acagatgaaa gtttagatag taatgtaggt
      121 caaaatgtac aaacaggaga tcaaagcaat ataatgctag atttagcatt aatgttcatt
      181 agcttgtttt ttttaattaa aaatctaaca aataaatact taagacgtaa ataacattta
      241 ttgtgtacat atttatttta ttattttatt ggataaacta tagtgactat aaatagattt
      301 gtgtaaataa aaatctattt atagtcattt ttgtatttaa cttaaaagct ttgaaataat
      361 tttcatatag aaaagagaat tttttattaa aagagattaa tggaattgat atcattaatt
      421 caattttagt agttatgttt agaagatgat tttaatctat gtatagttgt ttttgttaga
      481 ataataattt gtaaatacaa gccaaacact caatattatg ttgagtatgg aaatatgatt
      541 gtatattctt cagataaaaa tttgaatttg aagtgataat tggtactaat ttatggaggt
      601 tatgttaaaa aatcatagat tctattaggt gattttttca gttttataaa aaacaatacc
      661 catctgatat aaaaatagat tttttaaaat taatatcttt tatactatta aaccattaaa
      721 gatgatagtc tttcctcata atatatttat ggaagaaaga agatttagac ttattgtaat
      781 aatattcaag ggaggtagct gaaaatatat caactaaaat ggatatacta ctatgtaatt
      841 taatggataa cttaactata gaaaaagact atctataaat atttgaaata aatcttagta
      901 taaattatta gcagtttact aatgtttttt tgtaaaaaat caatcaaaaa gttatataat
      961 aactttatat aacaaataga aagaggtgaa actacatggc taaaattgac aatatgatgt
     1021 ctatactgtg gatgttaaac tctgacaaaa aaattacagc aaaacagata gctgaaaaat
     1081 tagaaataaa tataagaaca gtgtaccgat atattgatgt actttctgcg agtggagtac
     1141 ctataatttc agatacaggt cataatggtg ggtatagcct tttaaataat tttactaaag
     1201 cacctctttt ttttgatata gaagagcaaa aatctctact tcatgcagca ctatttgcta
     1261 aaaaagaagg atacttctta gacgaagcat tagataaatc gatattaaag ttaaaaatgt
     1321 attcaaatca aaaacaagaa gatattttaa caaaccactt aagagccctt gaagtaataa
     1381 aaccaattgg gaaagtgtct atagaatcag tacttaaaaa attggagaat agtatattaa
     1441 aggagctatc tgtagaaatc aactatcatg caggtcgtaa agcaaaatca aaatatagaa
     1501 ttataaatcc atatggaatt gttcactgga ataataattg gtacgtagtt gcattttgta
     1561 atatgagaaa tgaggtacgt agtttcagag tggataggat tagtgaaatc atagaaacat
     1621 caaatacatt taacagaccg acagaatttt cagcaagtga attttttata aaaggaatta
     1681 tacctgaaat aaaagatgaa caaaatataa ttcaattagt tgtagaaggg agtatagatt
     1741 ctttagatag tttaagccaa cattggtttt tagggcacta cttgaaagaa agaacaccta
     1801 ataaaataat atttatgctt gaagaggaag taatatgcaa gtacatacca aatatacttt
     1861 taccttatag aaagacaata caagtaattg aaccactaag ccttaggaag aaaataattg
     1921 aagatttact agaattaatt gattattatc aaatttaata gcttaactga ctgaatatgt
     1981 cagttaagtt attttataat tagatatata aattaattac ataaggagta aaaaagatga
     2041 aaaatagaaa agtatatatg tatgtatttg atactatgtc agattgggaa gtggcatatt
     2101 taactgctga attaaataca ggaagatatt ttaaaaaagg attaaaacca ctaaaagtaa
     2161 ttactgtagg aattgataaa aatcctatta taacaatggg tgggttaaga gttttacctg
     2221 aaattacagt tgatgagttt aatatggaaa gtaaggattt attaattttg ccagggggaa
     2281 atacttggtt atccatgaat catgagataa tattagaaaa agttaaagaa gctttaatac
     2341 aagattctat agttgcagcc atatgtggag ctacattagg cctagctaaa aaagggctat
     2401 tagattttag aaatcataca agtaatgact tagagtttct taaaatggta ataccaaatt
     2461 actctggaga aaaatattat aaaacggaat ctgtagttag tgatgaaaat ttagttacgg
     2521 cttcaggaat tgctccgttg gaatttacgt ttcaagtatt gaaactttta gatgtttttg
     2581 aatcagaagc attaaattca tggctaaatc tttacaaaac tcatgactca aaatattttt
     2641 ttgaattaat gaattgtaac aaataaattt aaaacttatt tttcaattta atatggtata
     2701 gcactgtgat ataaagaaca aaaaattaca atctggtgga atagagtagt ggtttctaat
     2761 atagatttct ttttggtgaa tttaaatttt atttaaattt aaattctaaa ccactttcta
     2821 tatagccaac agaaaagtgt taaaaaatta tcatatatat aattactact tatagtaaca
     2881 caaatagagc taataactcc tataataaaa tttatcatta gttacatata gaataaacct
     2941 cagttttgat tactgtagga actaggatta tatgaagcta ccactcatag atttcagttt
     3001 tttctgttgt atcatagcat agaatagtaa atttatctga aactttattt taaatttaga
     3061 atttgcatat agataaatta tgggcattat tctgatgatt cgtctccaat aattaaaaaa
     3121 agaatgataa aatacttgaa aatactagtc tttattgact agtgcttttt tatttcagtg
     3181 ataaaatata ccaattatac ttcagttaca ggaaatgatg tttttgaggg tacattggga
     3241 ggcatttagg ttgtataatt ataagtttca atgttatatg ctcattagaa taatagttag
     3301 taaatgatat gattgagatg atagatgaaa taaactaatt tagtactgta ttgtaatgtt
     3361 tattataaaa tcttttataa aatatattta tgaagatatt attgaatatt ttcaatattc
     3421 tattgcaatt tatttggaaa agttatatat ttataacata aggtgttata aatatataac
     3481 ttttaagggg tgattttata tgtctaaatc agagcttggt gttaaaacaa atcttgtttc
     3541 agagttactt atgatatcct atttttttat agactcatta ttaaaaaagt ttatttttaa
     3601 agagggaaat ctttgtatta cttttataat tttattcgct ttttgggcat gtgacttcat
     3661 gtataataaa aaatataatg atttagttga cgaggcgtca aaacttatgt tattaaaggt
     3721 tgatcatatt gcatcaaaaa taatgttata ttctattttg ctaatatctg ttttcttttc
     3781 agcaaattat acaagaggtt tggatatatc aaatttggat ataggtgtaa ttctcttagc
     3841 tattttattt atacaatctt tatctaaatt aattttgtat atacattttg atagaaaggg
     3901 aatatgcaac taagtgataa tattgataaa aacgaaaatt aaagagtata gagaatataa
     3961 tttttaagga gtgattttat atgtctaaat cagaaactgg tgtaagatca aagcttatcc
     4021 tggagttgat tgtaataact tattttttta tagctgtatt agccactaag tatattttta
     4081 aaggtccaag cactgcttct cttccagggt tgagttggtt aatagttttt ggatgttatt
     4141 caatttataa taaaaaatat aatgatttag ttgatgaatc atctgaattt atactatcaa
     4201 aggttaataa gattgcaata aaaataatga tatattctat agtaataata tctattttct
     4261 ttgcaacacc ttatacaagt aatataaata tatcaaacct agatacaggt ataatcctca
     4321 ttgcagtttt atttatacag tctttatcta aattagtgtt gtatatatac tttgataaaa
     4381 gggggatatg taactaagtg gcaatattga tgaaaacaaa aattaaagaa tacagagaaa
     4441 aactccttat gacgcaaaat gaacttgcta aattggttgg ggtaagacgt gagactattg
     4501 tacacttaga aaatgggaaa tataatcctt ctttgaagtt agctatggat atcgctaaag
     4561 tattcgatac tacagtagaa aatttgtttg aatttattga agaagaatag tggaaagttt
     4621 ataaacattt ataagatgga taatgaaata tagttattta attattaagt ttattaaaaa
     4681 tatttatata atatatgatt aaggtcagat tataattgtt ttaagataaa atgtaataaa
     4741 atttaatgga gaaattttat aggtagataa attttaatat ttataagatt atgttaagga
     4801 aacacttaaa aattagatta aaattgtggg tatttaaatc aactaaaaga tattgactat
     4861 ttagtcaata tcttttttta ttaaaaagga atataaagaa gttaggctaa aaattgggat
     4921 aaatatgatt tatatagcat catttaatta aaaggagcta tattagtatt cattcataca
     4981 attggataat atacaatgtc agccttgctt tatggtgttt gtaataaacc tatttcagtt
     5041 tctattgtaa ttaatatgca agaatttaag ataggagtat ctatggctta tggtgtatta
     5101 gtaattggta tatgctatat agcattagga ataattttta aattagatag aaaaagattt
     5161 acataagata acaaaggcta atttataaat tggtgcttag aaaaccaaat cactttatta
     5221 gctagagatg aatttggagg gtgtcacttt ggtgttttat gcaaagttta tggaagtaaa
     5281 acattagata atcgtgagta agatttctat aaatcgtata tactattgga atccaagaaa
     5341 aggtattggc caaatagcta atatcttttt aatttttttg actctaatat agcattaact
     5401 attgcatgag tatctttaaa tttatagtta atgtatctta attgtttatt ataaaatcta
     5461 ggaaggctaa agcataaaac acttaaaaag agaagatgta catgagaaat ataattaact
     5521 atgatgcaga cttctaaaaa ttatttagtg aaaaggaact tagagtgtat aataaaagtt
     5581 ccttttcact aaggaaaacg attgttattt tctgagcttc attaccctga tattatttaa
     5641 atataaacaa caacaaaatt aacaagaagc aaattcaacc taaaatttaa aatatcggga
     5701 ggtacaatat gttaataaat atgaaggaaa tgctaaaagt ggcacaagaa aatcaatttg
     5761 ctgtaccagc atttaatata ggaagtgggc aaatacttaa agcagtagta cagagtgcta
     5821 acgaaaaaaa tgcaccagta atacttgcaa tacacccaaa tgagctaagt tttctaggag
     5881 atagctttgt agctagttgc atagaagaag caaataagag taaagtacct atggtaatac
     5941 acttagatca tggggaaaat aaagaacaaa tattaaaggc aataagatgt ggatttacat
     6001 cagtaatgat tgatggctca catttaccat atgaagagaa tgtagctata tctagggaaa
     6061 tagtagaaat agcaaaagga ttaaatgtgt ccgtagaagg agaacttgga acaataggaa
     6121 caacaggaac atcaagtgaa ggtggtactg atgaaataat atatacagat tcaaaattag
     6181 ctaaggattt tgttgaaaaa acaggagtag aaacactagc tattgcaatt ggtacagcac
     6241 atggtatata tccaaaaggt tttaaaccag agcttaaact agatttatta aaagaaataa
     6301 gagaagtagt agatatacct ttagttcttc atggtggttc atcaaatcca gatgaagaaa
     6361 tagcacaagc agttaaacta ggagtttgta aaataaatat ttcgagtgat gttaagtcgg
     6421 catattataa gaagtgcaga gaactattag aacaaaaccc aagcttatat gagccagata
     6481 ctatatatcc accatgtata aaagctgcaa gagaagttat agagtttaaa atgaatctat
     6541 tcaatgctat agataagtta aagtgctttt ataaaaataa aaattaatta tgaggtaaca
     6601 aattaaaagg aggggagaat ttatgatagg taaaatacta cgaagcgatt gtattgtact
     6661 agataaacaa ttacaaacaa aaaaagatgt aattaattat atggcaaatc atttgtacca
     6721 tggaaattat ataaataata aagaaaagtt tatagctgat attaataaac gtgaaaaaga
     6781 atcatcaact aatatgggta atttaatagc tatacctcat gctaagtcaa atgtagtaaa
     6841 tcaacctgta atgatgtatt taagaacaga tagagagatt acagataatg atggtcaaaa
     6901 acttaggtca ttttttatga tagcagttcc agaatcaggt tcagatgaac atcttaagat
     6961 tatatctaaa ctagctacat atctaatgga agaaaatttt cttaagcatc tactaagtgc
     7021 agaaactcca tacgaaatat taagtatatt taataataaa gctgcagaat caggagattt
     7081 tagtaataat caaaataaag gtcttatagt tgggataaca ggatgtccaa caggtatagc
     7141 tcatactttt atggcaaaaa aagcattaga ggaagcaggt caagaacttg gatatgaagt
     7201 taaaatagaa actcatggag ctataggtgt agaaaataag ttgactaaag aagatataaa
     7261 aagagctgaa tacgtaataa tagcttgtga taaagaagtt caactgagta gatttatagg
     7321 aaagaaagtg ctacaaaaga aagtagtaga tgctaagaat gtttcattag ctaaaaattt
     7381 aattataaac gctgaaaatg gaatggctaa agaaattaaa ccaggtggaa agactttaga
     7441 agattcaaaa gaaatgcttc aagggtcaga gaaaaagggt gtttataagc acttaatgag
     7501 tggtgtatct gaaatgattc catttgtagt gataggtgga attggtatag ccatagcttt
     7561 tatgtttggt atatttgcat cagacccaac tcatgaaaca tacaacccta tagctggatt
     7621 ctttggacaa cttggaggcg attcagcatt taagttattt ataccgatac ttgctggttt
     7681 tatagctaaa tcaatagcag gaagacaagg atttgctcct gctatgatag ctggttttat
     7741 ggcagttatt ggaggttcag gttttatagg tggtatggta gctggttttg caacaggata
     7801 tatagcttta ggagtaatga agataacaga aaatttacca gatgtattaa aaggagtaaa
     7861 tgctgtattg atatgtccac ttttgattgc atttacgagt ggagctataa tgttctttgt
     7921 agttaatacg ccagcatcat ggttaaatga agctttacaa tcttggttac aaagtatgtc
     7981 tggaactaat aaagtattat taggtgcaat attagcaggg atgatggcat cagatatggg
     8041 aggacctatt aataaaacag cttcagcttt tggattggct atgttttcaa gtaatatatt
     8101 tgaaccatca gcagcattaa tggtaggagg aatggtacct ccattagcaa tatcattagc
     8161 tatgttaata ttcaaaaata agtttactaa agaagaaaga aagtcatctc taccaactgc
     8221 tataatgggg gcatctttca taacagaagg cgcaataccg tttgcagctg cagacccatt
     8281 aagaatgatt ccagcaaata taattggttc ttgtataggt ggggcaatat gtatgagttt
     8341 agatataact ttaatggcac cacatggggg aatatttgta ataccatttg catgtagtgc
     8401 accagttgca tatatagctt gtatattgat tggtacagta ataacagcat tgattatagg
     8461 ggtaacaaag cctactataa ggagtgaaaa tagtgaagtt gaattacttg gtgcttaaat
     8521 tataaataat agtaaaaata attaatggaa taacaacaag tatatagaat aataataagg
     8581 atatttagaa tcagttaact acttctaaat atccttaatt tttattttga aattatatta
     8641 tcttattata tcaatttagt aaggtgtatc ataaattctt ttatgataca gaagtatctt
     8701 agtaatttta catagttagt aaatatgtta aaatagtact taatataaac atagaaatat
     8761 ataaacatag gtagggaggg ctaagtatgc ttgtgtcgag gcaaattgaa tttcttaaat
     8821 tgatactaaa cgaaaataaa tatagaccta taaaatactt taaagataaa ttaaatgtat
     8881 ctgataaaac tttacaaaaa gatttgaaga tgattgagaa atatttagaa acttttaata
     8941 taaaaattga tataaaaaga ggctatggaa tattaataga agatttagca aagaagaaca
     9001 tagacttaat taatagttta aatatacaat cgaaggaaaa taaatcttta tcagtagagc
     9061 agagaagaat ggagatttta aagtatttat tgctaaattc aaataatata acttcaataa
     9121 atcagttagc agataaatat tatgtaagta aaacttctat agtaaatgat tttaaatata
     9181 tagaggcatg gataaaagaa tacaatttaa aacttaataa aactttagaa ggaactaaga
     9241 ttataggtaa agaagtggat ataaggaaat cgattgccaa aatgatggat gatttattag
     9301 atgaaaatta tgaacaacat gatatatctg agttaacaag attagattct gctacattta
     9361 gtgcattgat aaatttattt gatattgatt ctattatatt tgtagaaact ataattacag
     9421 aattagaata caatttagga tatactataa atcagcccta ctatataaat ttaattaccc
     9481 atatacttat atgtttaaag agaatcgaag aaggtaatca aatagaatct cagaaagaaa
     9541 gagaaatttc tgtagataat ttggacgagt tagtatataa aaatgtcact acacttatag
     9601 ataaaataga aaatagatac agagtaaaaa taacgaaaga tgaacttatg tacatatata
     9661 tttttttggt atcatctgga tttagtagcg aaaataatag tagttacaat gatgaatcag
     9721 atagattaag tgaaagtgaa aaagtttcat ctataatgat agagaatatg tcacaatttt
     9781 taaatataaa tctcaaaaat gatgacttac tacaaaaaag tctagcatct catgtaaggc
     9841 ctatgttaaa cagattaaga tatgatatcc aaataaaaaa cccgttgtta ggagagatac
     9901 aagagcgatt ttcagatgtg ctgggattat gtatgatgac tataaatatt atgacagagt
     9961 atgataatct gaagaatatt agtatagatg aagtttcata tcttgccaca tattttcaag
    10021 cggcaataga aagaaatatg agtagtaaaa gagtaatagt agtttgtcat acaggatatg
    10081 gaacatctca gctccttgca gccagattaa aaagagaatt tcctgaatgg actatagttg
    10141 atatagttcc tatgcatcag ttgagtaagc gaaatttaga tgatgtagac tttgtaatat
    10201 ctactgtaaa cttagatttg aaagataaat tacatatagt tgtatcagta ctattaatgg
    10261 aaaatgatat taataatata aaaaatgctt tactttctaa acctaaaaaa agtatgaact
    10321 tagatacaaa cttattagga atgtatttag aagataatat atattttaat tttgatgtag
    10381 ctcagatgga aagtttaata ggtgtgaatt tagggagtaa atatgaatct atttcattag
    10441 gaaaagattt aaatatatat atacataagc aaagtaaatt aaataaaggg ataatgaata
    10501 tcaataatgt tactagaact attgatattt atttagaaat tagtaatcaa agttttttaa
    10561 agaatatttt aatggaaata tcaaatttat ataggcaaaa gaactatata aactatataa
    10621 tagattgcaa gagcaaagag gatattaaaa tattatttaa gaataatcta ttggagaaaa
    10681 caaatggaaa ttagagaaat attaacagaa gaaagcatta ttttagattt gaaatcaact
    10741 acaaaagaag gcataataca ggaattagta gataaattat acgatacagg aagtataact
    10801 ttaaaaagta agtttataaa ggcattaaaa catagagaaa aaataggctc tactagtata
    10861 ggttatcaaa tggccatgcc acatggaaaa acaaaatatg taaagaaggc atctgtagta
    10921 ataggtaaat ctaaaaaagg tgtagattgg ccaagtatag atggcttacc tgtaaaagta
    10981 ataattatgt ttgctatgcc acaatctgga ggcaatgaag atatgatatt aatatctaaa
    11041 atagcttaca ttttaggtgg taaaaatata ggtgaaagac ttttaaatgc acatacaaaa
    11101 aaagaaatat tagatatatt ttatgaagtg taggtattgt ataaattata aatttgaggt
    11161 ttttaaaata aaatgtgtat tcttttaaat agtataaatt aatttttaga cactagagag
    11221 gagaggatat atatggcaat atatttagaa atgcctaaat taatacatga atttcctttt
    11281 cgtactctat caaatgaagg agaagtatta acaacaccac actggcataa ggaaatagaa
    11341 atattactta taacagaagg tgtagtaaat ctatttataa atgacaagcc tatgcaatta
    11401 aaaaaaggcg agatagtgat aataaaagga ggagatattc attatatact gccatcaccg
    11461 ggaagtgaaa gattagtatt tcaatttgat atatcttttt ttaatgattt aattttatta
    11521 aatgaggaga aagaaagctt aattaattta ttcagtagta taaaaaaatg tagtagagat
    11581 tggtcagcaa aaataagaaa gtcagttttc gatatattga tagatatcta caatgaagac
    11641 ctatacaaaa tagaaggata tagttatgca ataaaaggta aaatgtataa tttaattcct
    11701 atattatata gacagattcc tagagaaatt gaagaaaata cagtagaata tgaaataaac
    11761 tctaaagaga tattagagag attgaacaat atattcaaat atgtagaaaa aaattataaa
    11821 caacctataa aattagaaga tgtgtcttat gaagtaggat ttagtgtata ttattttact
    11881 aaatttttca aaaaaaatac aggaaaaaca tttataactt ttttaaatga atatagatta
    11941 gaaaaagcaa agtggatatt acttaataac aatatatcca ttgtagattt ggttgaagaa
    12001 gttggttttg gaagtacaaa aactttttac agagtattta aagaaaaaat tggagtctct
    12061 ccattagaat ttaaaaaaag atataatagc ttggaaaaaa aagggagtgt ctcaaaatga
    12121 acttagttca tgaggcactt tcttttatat gaaatcaaat atattttcag tatttcaaca
    12181 atgaaaattc cattcattta taaagtctaa attttagttc tcaatacaac ctctatttcg
    12241 aaataaatcc ttttatatat ataaatatac agcaatatat gagaataaga taacaataat
    12301 gaggatataa aaatgtattt gctatatata taattatata catagatatc taatattgat
    12361 atttaatatg aaagtattga aaatagacaa tattaattat agtgagtaaa aaatataatt
    12421 ggatttttaa attgaattat ttaaaaggta tagtatgaaa aaaatcttat aactaaatat
    12481 gagatagaaa ttataaaact ttatattgtg aaagaggtag atgcatgaaa ttagggaaag
    12541 attttttatg gggaggggca atttcagcca atcaaagtga agggttttat ttagatggag
    12601 gaaaaggttt atctcagttt gataaactcc cattaaatga taagagatta aaagatgtat
    12661 gtttagatga ggataatatt ttaaatgaaa ataatcaata ctatccaagt catataggga
    12721 ttaaattttg tgaaaattac aaagaagata tagcaatgtt agcagaaata ggttttaaat
    12781 gttttagatt ttctatatct tggtcaagaa tattcccaac aggagaagaa agtgaaccaa
    12841 atgaaaaggg attacaactt tatgataata taataaaaga attaaaaaaa tataatatag
    12901 agccattaat aacgataagc cactttgata taccttattc tctagttgaa aaatattctg
    12961 ggtgggctga tagaagagtg gttaatttat atgtaaaata tgctgaaatt ttgatgaaaa
    13021 gatataaaga tgatgtcaaa tactggattc cttttaacga aatgaatatg ataatacata
    13081 ttccatatat aggtgctggg ttaactttta tagctgatga aaatcaactt cagaaaaaat
    13141 atcaagcagc acaccatcaa ttattagcta atgcaaaaac tatagaaata ggaaggtata
    13201 taaataaaga atttaagttt gggtgtatgt tagctgctgg aaaaacatat ccatacacat
    13261 gtaaaccaga agatgtattt gcaactttag agcatgaaag gcataatttg tttttttctg
    13321 atgttcaagt taggggtgtg tatccaagct ttatgaatta ttatttaaaa tcaaatcaaa
    13381 taaaattaat aataaaagag gaagatttat caacacttaa ggataatact gtagattttg
    13441 tatcttttag ctattattct agtgcttgta gttcagctag agctgaaggt ttagaaaaat
    13501 caaaggcaaa cggaccagaa accataaaaa atccatatct tccaaaatca aatagtgtat
    13561 ggcaaaacga ccctgtaggg ttaagaataa ctatgaatca gttatatgaa aggtatcagt
    13621 tacctttatt tatagtagaa aatggactgg gtactcaaga tattgtaaat gaagatggaa
    13681 aaataattga tgattatcgt atagattaca tgaaagaaca tattaaaaat atgattcttg
    13741 gagtaaatga agatggaata gagcttatag gatatcttat gtggggatgt atagatgtaa
    13801 ccagtgtaag tgaaggaaag atgacaaaac gatatggcat aattcatgtt gattctgatg
    13861 actatggaag aggctcattt aaaagaacta aaaaacaaag tgctttttgg tataaaaaag
    13921 taatagaaac agatggagaa attttattta atgatatgga aactcatgca taattcattt
    13981 taagaaagga gtgttattat gagtttaata tttactacta aggaccaact tatagagcaa
    14041 gggtttagta aggatacaat aaaatccaat gaaacgctgt ttacactagc gaatggacat
    14101 ttaggagtta gagggaatat tgaagagtct gattttaata atgagtatgt agataatatg
    14161 ggtacatatg taaatggatt ttatgaagaa tctccaatta catatggaga aagcgcttat
    14221 ggctatgcaa aacaaaatca gactatctgt aagttaccta atgctcatat agtaaatttc
    14281 tctattgaag gagattattt tgatttatca aaaggtatta caagtgaaca ttctaggata
    14341 ctagatttaa atgaagggat tcttaaacgt tcatttatat gggaaaactc ttgtggtaga
    14401 aaagttaaag tatctataga aagattagta tcacaagata tagaagaatt aatgatgatt
    14461 tcatatacaa taacaccatt gaattttaat ggaaaaataa aatttaaaaa taaaatggaa
    14521 aatagtatgg agaagtttaa ttgtgaaaaa gtagatgacc caagagtggc atctataaat
    14581 aagaagcaat ttaaaattaa tgtaaaaaaa tataacaata agtattttat gaatttagtt
    14641 acagaaagaa gtagattagg gttatggtgt gggtttgatt catatattac ttgtggaaat
    14701 attacaaatg agacctataa tgtttcagat gaatgtattg agcgagaaat agaagtctat
    14761 gccaaaaaag atgaaaggtt aaatttagaa attgttgtag gctatagtag agtatattct
    14821 gatttaaatc taaatgaaga acgtttaaaa tcattagaat gtctggagtc gttaaaatgt
    14881 ttagaatcag aagcacattt aaaatcatta gaattggttt taagagaagc atgtaatatt
    14941 ggatttgata aagtcaaaaa tattcagaga aagaaaatga atgagttttg gacaacctct
    15001 gatgtagaga ttgaaggcga taaaactctt caactgggga taaaaaccaa tttatttcat
    15061 atttatcaat cagcaggaag agatggaaag actaatatat cagcaaaagg tcttacaggt
    15121 gatggctatg aggggcatta tttctgggat acagaaatgt atatattacc attttttata
    15181 tatactcaac catccattgc tagagcttta ttagattata gatactcaat cttagatgca
    15241 tcaagagaaa gagctagaga acttggaata aataaaggtt gcttatattc atggagaact
    15301 ataaatggta atgaatgcag tgcatattat ccagcaggaa cagcacagtt tcatataaat
    15361 gcagatatag cttatggtat tagaacgtat tttgaagcaa ctaatgatga agaatttatg
    15421 atgcaaaatg gcttagaaat tcttatagaa acagcaagat tttgggttga atttggagat
    15481 tatatagaat caaaaaataa taaattctgt ataaatggag taacaggacc agatgaatat
    15541 acagcaatag taaacaataa ttactacact aatttaatgg ctaagtataa tttaatatat
    15601 gcagtacaga tggtagataa atttaagcat aatttatttt caaatgaagt atttagaaaa
    15661 gttaaattac aagaatatga agtgaaaaac tggataaatg ccgctcaaaa tatgtattta
    15721 ccatatgatg aagagaagaa aataagcaaa caagacgatt catttttaga aaaatcagta
    15781 tgggatttta aaaatacacc aaaagaaaaa tatccattac ttcttcatta tcatccatta
    15841 acaatatata gatatcaagt aaataaacaa gcagatactg tactttcagc gttgcttttc
    15901 cctgatgagt ttagcttaga acaaaagaag agagattttg aatactatga aaaaataact
    15961 actcatgatt catctttgtc aaggtcaata tttggaatga tggcaagtga aattggaaat
    16021 catgaaaaag cttataacta ttttatggac acagcattaa tggatattaa taacctacaa
    16081 aaaaatacaa gtgatggaat acatgctgct aatatgggtg gaacatggat gagtttagta
    16141 tatggatttg caggaatgaa aataaaaaat gataaattaa gttttgaacc aaggatacct
    16201 aaacactgga aaaatattaa atttaatata ttatttagag ataatttagt ttctgtaaat
    16261 atagaagaat ataaatctta ttataagtta atcaaaggta gaaatataac catattacat
    16321 gataataaag aaataaaatt atcaaagaac ataatagaag ttaataattg ttttaaaggg
    16381 agtaattaat atgaaagcag tcttatttga tcttgatgga gttataacag atactgctaa
    16441 gtatcatttt gaagcttggc atgagatagc aaaatcgcta gatatagaaa tagatgaaac
    16501 ttttaatgaa aaattaaaag gcataagcag ggaagaatca ttagataaaa tattgttatc
    16561 tgctaataaa gtagatagtt atactaaaga ggaaaagtta aaggtgtgtg aagaaaaaaa
    16621 taacatttat ataaagttaa taaactcatt aacatataaa gatatattac cagggataaa
    16681 tgagcttata aaagaactta aaaaaaataa tgtgaaattg ggaatagcat ctgctagtaa
    16741 gaatgcacct aggatattag aatctttggg aataaaagat gaatttgatt gtatagtaaa
    16801 tccatcttta ttaaaaaggg gaaaaccata tcctgatatt tttattgaag ggagcaagat
    16861 tctaaattta aaacaatatg attgtgtagg aatagaagat tcttattcag gtattaaagc
    16921 tataaatgct gctaatatga catcaattgg tgtggggaaa aaagaagtac taggaaaata
    16981 tgaccatatt gtagaagata ctagcttatt aaattacaat acactattac aagcttggag
    17041 taaaaagatt aatttggatt aaaattatat taaaaattat tttaaaagag aggataaggt
    17101 atgaagaata aatatgaaga agtagctcaa ttgataattg atggacttgg aggaaaggat
    17161 aatataattg acttaactca ttgtatgaca cgattaaggt tcatcttaaa agatgaaaag
    17221 aaagtcaatg cagataaatt aaaatctata gataaggtag ttggagtaaa ctcaacttca
    17281 actcaatatc aggtcataat aggtaatgag gtaggtgttg tatttaatgc aataataaat
    17341 aaggggataa ataccacagg agatattaaa agcgatataa aaaataaaaa taaaaaaaat
    17401 agtattttaa ataatataat agatacaata attggttgta tgacacctat gataccagcc
    17461 cttacagcat ctgggatgat aaaagttata ttatctcttt gcaccacttt taattggcta
    17521 tcatcaaatt caagtacata tagagtatta gatataatag gagatgtagc attttacttt
    17581 atgcctataa tacttgcaat aaatgcagct aaaaaattta atgttaatac atcaatagca
    17641 gttatagtag taggtgtgtt tttacatcca aatttctctg catgggtatc aagtggggac
    17701 cctatatcat ttataggagt accaattcaa ggtgttatat atgcagcatc tgttatccct
    17761 gcacttttaa cagtatggat gatgtcatat atagaaaaat tcattgataa attaacacct
    17821 agcatgttaa aaacaatttt aaatccaact ttagtattat taataagtgc gccaatagca
    17881 ttaatagtaa ttggaccaat aggaaatttc ttaggagagg gattagctag tataataaat
    17941 ttactacaag gaaggttagg atttataatg gtttgtttat tagcagctgc aatgccattt
    18001 atcgttatga cagggatgca tcatgcattg actcctatat tcatatcagc atttgcaact
    18061 acaggacaag aatcgctaat attaatatct caagtttgtg ctaatttagc gcaaggtggc
    18121 gcgacattag ctgtagcatt aagaagcaaa gatagtaaga tgaaacagtt agcatcagct
    18181 gcatggatat cagctattat gggtataact gaaccagctc tttatggagt tacattgaaa
    18241 cttaaaaaac ctgctatgtt agcatctata ggagcaggaa tcgcagggtt atttgcagga
    18301 attactcatg tgactttata tgttccacaa aatagtataa tggcagtact tggattatca
    18361 ggggaaaagg ggatttcaaa tatagtaaat ggacttatag ttatatttat agcattggtt
    18421 gctccattta ttatgacata tgtttttgga gttgaaaaaa atgttaagga aggtataggt
    18481 aaattaagga agtgtgttaa atagtatgag ataaaaaaat tcatgataaa tatttataat
    18541 aaaagtgatt aacctataaa acttagtaaa taatagttat ataataatta agataaactc
    18601 aatttaaaac tttaaaaaat acgattctta aatagtcaaa ctttagtaaa atatataaaa
    18661 atatgttttg ttaaggtttg gcatattttt tattttggag aagaaatttg atacctatat
    18721 tcctactaca ggaagatggt ctcttgggtg tactatagga tttataatgt ataaaattgt
    18781 acatgtaaaa gttattagtc cattaggatg gtgattaata aataatatga ttaatagaat
    18841 agtttagcct tgtattgtaa tgtttattaa agaatcattt tatgccataa gttataagca
    18901 ttttttatgt ggagagttct ataaaatgta ataaaaaagt agttttataa tagtatctgt
    18961 aattcttaaa tatttatcat gaaatttttt ataaattata cttataagat gatatcaagt
    19021 attcgcaata ttctgttgaa atttatttga aagagtcata tatttataac ataaagtgtt
    19081 ataaatatat aaattttggg gagagattct gtatatctaa gctaaaactt agtattaaat
    19141 taaatcccac ttccgaatta ttgatgatat tatatttttt agatttatca ttgaaaaagt
    19201 ttatttttta taattttact aacttttggt caagcaatct tatgtataat aagaaatata
    19261 atgacctatt aagatttgta cagttttaga aaatatatca ttctcaaaaa agcttgcttg
    19321 tataagtttc tctaatattt tgtgtcctat atactctgtt ttaattaata atcaatctta
    19381 aaagttttgt atgaaaggaa ataatggtat gaaaaaaatg ataattgaag tttcaaactt
    19441 atctaaagtt gtagacttgt taaacacaga acttactata ctaaggaata tagatttata
    19501 catagaagaa ggagaatttg tttctataat gggtgctagt ggtagtggga aaagctctct
    19561 aataagtata ttaagtggtc ttgataaaaa ctatactgga aacgtgaaag tttgtggtga
    19621 gaatttatcg aaattaactg atgatgaact tgctgaatat agaaatagaa agatagggat
    19681 tgtatttcaa tcatttaact taattacatc aatgtctgtt gaagaaaata taaaattgcc
    19741 attgattttt tctgataata aagattataa aatagtagat aagatgatta aaaaggttgg
    19801 gttgacatca aaaacaaaaa ataatattaa acaattatca ggtggtgaga agcaaagagt
    19861 tgctatttca agagctctag tttgttctcc aaatatactc tttgctgatg aaccaactgg
    19921 atcattagat agtactaata gtcatgctat aatgaaattg tttaagaata taaacaatga
    19981 atatggtact acaatagtaa tggttactca tgatattcaa atggcagaat atagtgatag
    20041 gattataagt attaaagatg gaactattat aaaataggtg gtgatacatt gatatttcat
    20101 gaagtttata aaatatatag taagaatagt ttgaagaata ataaattatt aaaaatctct
    20161 tgtataatat ctattgtatt tgccacagca atattacttt ttacaagagt gttaacggat
    20221 acatattcaa gtgaagttaa gagaaatatg gctataacaa atggtggaga tataaaaata
    20281 caaaatatag aatataataa atactacttt acaagtgaac aaatagataa gttagaagaa
    20341 ttaaaaggta aagaatctat tgattttcag ttgggaagta gtatgaatac aaatatattg
    20401 tcaaatggta tgattgaaag tactgaattg actgtagtaa ataatataaa aatgcaaaat
    20461 acatatttaa aattaagaaa tgaaaatgat atagttttat cccaaaaaac agctaataaa
    20521 ttaaatgtaa atataggaga taaagtgttt ttaaaactac attcttcagt ttatgatgat
    20581 acatatttta aagttagtga tataatacca aaaaggtttt cattaagtac agctcaaaaa
    20641 gaagcagagg ttggccaaga ggtagttgga gaaagttatg tatatttgcc taatgaaact
    20701 aaatataatg tagcttatat aaatataata aacaaagaaa atgtgaaaaa tattaaaaat
    20761 gaaataaaaa atgtatttaa aaaccatttt gaagttagaa caactgatga actagaacag
    20821 tcaataataa agagaatatc tatgcaatta gattcaataa atttaattgg agctatttca
    20881 ttattaagca ctggaatttg tctatgttct acatttattg tatttatttt aaatcgaata
    20941 aatgattttt caacttttaa ggctttagga attaaaaaaa gaagtttatc ttttctagta
    21001 tttactgaac ttatgtcaat tactataaag gggattataa taggtattat tttggggatt
    21061 cctataacta tattctatat taacttacaa catattaatc tatttaatat ttctattttg
    21121 agtattatca aaaatatttt catttcaata gttattataa taattgaaac atcaatattc
    21181 tcattaattc ctataagttt tgttaaaaaa atacattatg aaggaataaa tagagataat
    21241 agtatgttgt cttcatataa atttaacttt attccagata taattcttgt aatattttta
    21301 acaagtattt cttttacaat atatgtgaag tcctttctag gtattttttt tattttagga
    21361 ttaatactac tagatttatt ggtatacagt ttgatatatg cattattaaa aatggtatgt
    21421 ttaattaaaa aaattattaa gggaaaatac tcgattactt ttatatatct taataatgat
    21481 tgtaaaacca atgcttttag ctctagtcta ttaacaataa caataatatt tgttttgttg
    21541 ttgtttatga tatctgaaat aacctttgct atgtttagca attatgaagt tgataatagt
    21601 ataaaaaatt caattgtata tcaaacaact ttagaaggaa aattaattac agataaaaaa
    21661 cttatcgaaa atgatataga ttattttcaa tattatccaa ttaaaataga tagtatagag
    21721 tcagtaaata atatttctgt taatgattat attgaaaaaa ttccatatga gaatagaaaa
    21781 gatgtaatga atgatttaaa tgacttaagt gttgatttat tcaatactaa acagacaata
    21841 ttaaaaagtg atttagagta tggaaactgg ttcaaagaaa atgataaaga aaatagtata
    21901 attataaata attatcttca tagatactta atagattata aactaggcga tactgtaaag
    21961 ttaagaatta atggaaagaa gatagacttt aaagtaatag gatttttaag tccaaaatca
    22021 ttgaacaaag gtgtagattt aggatatata aatataaatg aaaatatttc acctaaaacc
    22081 cttgatttat ctaaaaatca accagtaata tattttttta aagaaaagtt agataacact
    22141 ttacttagta aattattaca taatgataaa tatgctaatt tagaagacta taatgatttt
    22201 gcttattcta tgaaaacata tgttgatgat caaaagtcat tacttttgaa tattatattt
    22261 gctgtgtcat tgtcaagtat acttctaata ctaacatctc aaataattat ttttataagg
    22321 agagtactag attatcaaat tatgtataga gtaggaatga gtaaacgaaa attgataaaa
    22381 ataggtttat tagaaatgat aattgtatca attatccaaa gtactcttat agcaattttt
    22441 tatgaactat ttagattctt actaatttca ttgttgcaga gagcttataa tattaattat
    22501 ttattgattt taatagaatt tttagtagta ttgtctataa attgttttat atttatattg
    22561 gctcaaagaa atattaaatt agacttataa attttttatt gagacaaatc tagtatagat
    22621 tttaagtcaa atgaagaggt taataattga atttataaat cgaaaaacaa cctattgtga
    22681 gagcttaaat tactatagaa ggtcgttttt tattacagaa ataaataaga gatagagaat
    22741 agtttagagg tgagaaagaa aatataattt aaaacatata acaacatata atcttctaat
    22801 agataaagga tttaatgttg ttgattttaa aaattataat aaaactatta aaaatggact
    22861 ctattaaatt aatattaata agaataatta ttataactga caaaaagcaa cacaaaagat
    22921 tgatgaagta tatggaaata aaaagttgac aaaatatgtc tgatgtttta tcatattaat
    22981 tggaattagg tagtaattgt ttaaggacaa gctaagctta ttcattaata atagcagtat
    23041 cctaggaagg agtatgccca ttattatgga taagcttttt ttatgcttaa aaggaggata
    23101 atcatgataa ttaataagat attaaacaat aatgttataa tcacattaga tgataatgat
    23161 gaagaagtta tcgttatggg taaaggaatt ggttatcaaa aatcaaaagg caatctaata
    23221 gataaaacta aagtaaataa agtatttaga atatcaaata aagaaatatc aaacaaacta
    23281 caagaattac tcaataatat tcctatagaa cacatgaaat tatcaagtga aattatagaa
    23341 tacgcacaaa taaagttaaa caagaagcta aatgaaagta tttacatatc cttaagtgac
    23401 catacatatt ctgcaattca aagaatgaaa gaaggaataa atgtaaaaaa tgcaatcctt
    23461 tgggaaatta aaagatttta taaagaagag tttgaaattg gaatgaaagc actagatatt
    23521 attgaaaaca aaacaggtat aaaattacca gaagatgagg ctggatttat agcctttcat
    23581 atagtgaatg ctcagttaag tgaaggtcat actttggcat ctgatattac gaagttaata
    23641 caagaagtac ttagcatagt taggtatcat tttaggatag aatttcatga agaatcagtg
    23701 ttttattata gatttataat gcatttaaag ttttttgcgc aaagattgct tttagatagt
    23761 gcacatgaag gtgagacaga caaagaatta ctaagcatta ttaaatctaa atataataaa
    23821 gagtttgaat gtgtagttaa aattaaaaat ttcattaaaa aacaatataa ctacatatta
    23881 acagatgatg aacttatata tttaacaata catttagcta aagtagttaa agactcaaat
    23941 atgtaagtga aataattttt cagcagtata ttaagaatga ttgaaaggag tgatactaac
    24001 aaaattatat ttatggttgg atggtaacat tgagttggcc aaaccttcaa atttcaaaaa
    24061 attaatttaa acgaaatatg gaggagaaaa atgggaaaat acaaacaatt agcacaagag
    24121 atagtaaaca atgttggtgg aaaagaaaat attagtggat tagtacactg tattacaaga
    24181 ttacgtttta ctttaaaaga tgaaagtata gcaaatgaca atgtattaaa aaacatggaa
    24241 ggtattgtta ctgtaatgaa aagtggagga caatatcaag tagttatagg aaatcatgtt
    24301 gaagctgtct ataaagatgt agttgaaata attggtttag atgattcaag tacaagttca
    24361 gaaactaaaa aatcaggtaa tatactagat aaaggtatag atataatatc aggaattttt
    24421 cagccagtgt taggaataat ggcagcttgt ggtatgttga aaggatttaa tgcattattt
    24481 gtagcaatgg gattatatag tgatgtatct ggtggttata tggtaataaa tgcagcggga
    24541 gatgcattat ttacattcct tcctttgttc ttaggatata cttcagctaa gaagtttgga
    24601 ttaaaaccaa tgttgggatt agcactagga gctgcagtat gttatcctgc tatacaaggt
    24661 agcagtatat cagtaggagc agatgtgatg tacactttat ttaaaggaac aatgtttgca
    24721 tcaccagtat atattgattt ttttggacta ccaattgtat caattgatta tactggaaca
    24781 gtcgtaccaa ttatatttat agtgtatttt gcttctaggt gtgaaaaatt atttaataag
    24841 tgtgttccag atttagttaa gtttttcttt gtgccaatgc ttacattatt aataacagtg
    24901 cctgttgcac ttatagttat aggtcctata gcaacatttg gttctacact tatttcacaa
    24961 attgtaattt caataagaga ttttagtcca ctattggcag gtgctatagt aggatttact
    25021 tggcaaattc ttgttatttt tggtatgcac tggggattta ttcctgtata tataaacaat
    25081 gttatgactt taggatatga taatgttatg atgccattct ttgcctgtac atttgcaagt
    25141 tcggcagttg tgttggcaat atttttcaag actaaagata aaaaactaaa agagatggca
    25201 ataccaaact ttatatctgg tatatttgga gttacagagc cagcaattta tggaatatta
    25261 ttgcctttaa agaaaccatt tataataagt tgtattgcta gtggtattgg aggcgctttc
    25321 tatggattct ttaatcttag aaaatttata actggaggaa tgggaatatt tgaacttcca
    25381 gcaatgattg aaccagatgg gggaatgggt aacttaatag tagctctttc tggtatagct
    25441 atatcaatgg tcgtagcttt tgtattaact atgattttat ataaagatga gaaagtagaa
    25501 gagtctaaaa aagtaagaaa taagggtaaa gaagaaataa aagaagtcaa gtctactaaa
    25561 ttagaaagag aaatagtaac aagtcctata aaaggtgaag tattaaaatt aagtgatata
    25621 gaggatgcag catttgcatc tggtgtacta ggtcaagggg tggcaataat acctagtgat
    25681 ggaaaagtag ttgctccagt agatggggta gttacaacct tatttcctag tctacatgct
    25741 atagggattc tttctgatac aggtgttgaa gtgcttattc atattggatt aaatactatt
    25801 caattagagg gaagaggttt tgaggcatgt ataaaacaag gtgatagaat tacaaaaggt
    25861 caaactatat taaactttga tgttgatgca ataaaagagt tggggtatag tactgtaact
    25921 ccaattgtta ttacaaattc atcacaattt ttagatgtag tagaaacaga aagtaaaaat
    25981 attgaattag aagacaatct aattacagtc ttattttagt aaagattgag gtattagcat
    26041 aatctagtgc tttggttata attttaggag gctttgacta tgagttttaa gaatgatttt
    26101 ttatggggag gagctactgc ggccaatcaa tgtgaaggtg gatacaatga agacgaaaga
    26161 ggattggcaa atgtagatgt atgtccaaca ggaaaagata gaacagcagt tattacaggg
    26221 aaactaaaaa tgtttgattt tgatgatgag cattattatc cagctaaaac tggtattgat
    26281 atgtatcata attataaaga agatataaag ttatttgctg aaatgggatt taaagtatat
    26341 agaatgagca ttgcatggag tcgaatattt ccaaaaggtg atgaagaaac accaaatgaa
    26401 aagggacttc aattttatga aaatatattt aaggagtgta aaaaatataa aatagagcct
    26461 ttagtcacta ttacacactt tgattgtcca atgcatttag ttaaaaagta tggtgcatgg
    26521 cgtaatcgaa aaatgatagg tttctatgag aaattatgca atgttatctt tagaagatat
    26581 aaaggattag tgaagtactg gctaactttc aatgaaataa atatgatttt acatgctcca
    26641 tttatgggtg ctggtatttg ctttgaagaa ggtgaagatg ttgaaaagat aaaatatcaa
    26701 gctgcccatc atgagcttgt agctagtgca attgcaacta aaatagcaca tgaagttgat
    26761 tcaaataact taattggatg tatgtttgca gctggaagtg tatatcctta tagttgtaat
    26821 cctaatgatg tatgggaagc tacaaagtta gatagagaaa attacttctt tgtggatgta
    26881 caatctaaag gtaaatatcc taactatgcg ttaaagtata tggagcaaaa aggtattaca
    26941 ccagaaatgg aacctggtga tattgaatta ttgaataaat atacagtaga ttttatttca
    27001 ttttcatatt acaatagccg ttgtgttaga accgatgaaa atgcagatga tatggctgaa
    27061 ggaaacatat ttatatctgc taaaaatcca tatctttcat acagtcaatg gggatggcca
    27121 attgacccat taggtttgag aattacacta aatcatgtat atgatagata tgaaaagcca
    27181 ctatttattg tagaaaatgg attaggtgct aaagatatag ctgatgaaaa tggttatgta
    27241 gaagatgatt acagaattga ttatataaga gaacatataa aagctatgca tgatgcagtt
    27301 tctatagatg gggtcgattt attaggttat actacatggg cacctattga tttagtaagt
    27361 gctggtacag gtgaaatgga aaagcgttat ggatttatat atgtagatag agacaatagt
    27421 ggtaatggaa gtctaagaag aatgaaaaag aaaagttttg aatggtataa gaaagtaatt
    27481 gcttcaaatg gtgaagattt atattagaca agaaatctat gttaaataag aaatttgtat
    27541 taaataagaa gagtataaaa attaataata agtataattt ttaacttttt taactataga
    27601 aaatcaatat agaattattt tacattgtat tgatgcaata gtatgattca caaataaaat
    27661 tttagaaaat aaaattgtta agaagtatgg gaagtaagtg caatttactt tgtaataaaa
    27721 gatgaaaaag gcaagcttag gttttaagct tgtctttttt attatgtata aactatgata
    27781 ttttaaaatt ctatgaaaaa tttatttaat agagaaatta aaaatttaat ggtaatcaaa
    27841 ttctttacca atgaatataa aaaatgtcta cgtgttataa tagtttaaac taataaacga
    27901 aaggtagatg aatgaatatg aaataccaac atataataga agttgacaaa gaactttgca
    27961 ttggatgtgg gctttgtaaa aatgattgtc cagtaaacaa tataattata gaaaataaaa
    28021 agtcagtaat taaaaaacaa gattgtctaa tgtgtggaca ttgtgcagca atatgtccca
    28081 caaaagctat tgccttgaca ggatttgatg aacctcctat agaacttaca aataagccaa
    28141 agctagattc agatgaatta ctaatggcaa ttaaatctag aagaagtata cgtaaattta
    28201 aagataaaga agtttcttca gaaattgtaa agcaaattat tgaggcaggt aggtataccc
    28261 ctagtgctaa aaattcacaa gatgtatcat atattgtttt agacaataaa aagtcaattt
    28321 atgaaaacga agcagtgaaa ttttttagaa aaataaaacc tattgcaaat atagctatta
    28381 aatattcaaa agaagttgag attgacgata actttttctt taagcatgct cctattgcaa
    28441 taatgataat tacaaaagat aagattagtg gttcacttgc agcatcaaat atggcattaa
    28501 tggcagagtc ttatggccta ggtgttttat ttagtggata tttttcagat gtagcaaata
    28561 attcgccaaa gttaaaaaag cttttaggtc taaaacgcag taatcatgtt cttacaacat
    28621 tagtaattgg atacccagat gttaaatata gacgtactgc acagaaagaa gtagcaactg
    28681 ttagatactt ataagagagg gtggatttta tggaaaaaga atgtcaacaa agaatgcaag
    28741 aaataacgtc taaatttaaa gaatgtcgca aagctatctc tgctatgggt gatgagacta
    28801 gacaattgat tttaattgct ctcttagaga gtgattttaa tggtatacga gtgggagaaa
    28861 tcacaaaaaa aacacatctt tctcgtcctg ctgtatctca tcatcttaag atattaaaag
    28921 aagcagagat tgttaatttg cgtagagaag gaacgaaaaa ttattattat cttgattcaa
    28981 aaaaatcaca atggaagtca ctaacagagc taataaatct tatatttgtt ggaatacaac
    29041 atattagtga aaatgatata agaaaaggtg attaaattat acttgattta atacaaaaaa
    29101 gattgattta ggaactaaaa agttcacttt gagacactat cttttgaact atacccatct
    29161 taggagacag ttaaaatatg taaaactgta taaaacaatg ggtatagttc attttataat
    29221 ggtttaaata ttaagaatat attattctaa atagtatctt tctctgtttt gagttttatt
    29281 tttatactca atagcttcag tggggcaacc acaaatacat gccatacaat gagtacagtt
    29341 atttttccaa actggttttt tgttttttaa attaatatta tttaaaggac atagctctac
    29401 acattttcca cagccaatgc atttatcagt ataatgaaat cctttggcac taataattgt
    29461 cttataaaaa actgtattta ttataccact tttaattgta cctcctaagc cactaggagt
    29521 aatagtttca aattcatttt cattgcgtat atcagaaata atcctatata tttgtttatc
    29581 tgcttcttta atcatttgtt ttgatgtttc tttgtctgtt gtagaaaata aagctatata
    29641 attctctggc attttaattt ctgccatacc ttttaattgc cattccttat atttacatag
    29701 tttttgaata tagtttatgg attttgctgt atctccacca caagtcatta caaagtaaac
    29761 tctgttgctt cctagaaatt ttgtttcttt tataaaatcc gtaaccacta ttggcaatct
    29821 ccatgcataa gtaggacata caaatatgaa tggtttatct gctgatatta attcatctgt
    29881 tttttcctct tttataagtt gatttagtga tatcagttca tcatttaatt cttgtgcaat
    29941 tttacgagcc acatatcggc tattaccagt tccgctaaaa tataaaatca taataatatc
    30001 tccctaacta ttttttattt taactcttaa ttttttattt attatagtaa tttattgata
    30061 tattctattc aaatgtatgt aaaatttagt agttaagaaa attataacac attagtaatt
    30121 tttatactta ttggtaaaga atttgattac cattaaattt agcaacaaga catcaactgg
    30181 acttgtatat gagaagggat aataatttgc ttatgaaaga ttataaatat aaaggttatt
    30241 ttaaaggtgt agaaatattt gataatgtaa atgaccttaa cttaaatact ttaacaacag
    30301 ttagtagatt tgtgcttgtt tttttgttta cgataactta aggaaatatg ttacctgaat
    30361 aataaattta tataataaaa gtatataaat atatatatga atgttaagat tagttgatag
    30421 aatttaaata ataaatccaa tattataaac ataggaggta tgaaaaatat gattaatgag
    30481 aatttaaaaa gtctaagaaa aatcaaccag tatacacaag aagaattagc tgaaaaactt
    30541 aatgtttcta gacaatcaat agcaaaatgg gaaagtggag aatctattcc tgatataggt
    30601 agttgcatta aacttgcaaa attgtacaat gtcaaactag atgacttagt taatcattca
    30661 gaagaaaaaa caggtattat agtacctcct aaaggaaagt ttttctttgg agcagttgta
    30721 gttggtgaac gtggtcagat tgtcattcca aaagaagcaa gagaagtatt taatataaat
    30781 gcaggagata aattattggt acttggagat gaggaaagag gattaggaat tgttcatcaa
    30841 cgtgatttga taaattttat aggtcatgtg ggagtagtac gtaaagaaga atgatttaaa
    30901 aaaattataa aaggaggtat gaaatatgag taaaatagta ttttttagca ttcctgcata
    30961 tggtcatact aatcctacta ttgaagtagt tcgtgaatta gtggatagag gaaatgaggt
    31021 attgtattat tcttttaatg aatttaaaga taaaattgaa ggtgctggag caaaatttat
    31081 ttgttgtgat aaataccttc cagaattact ccctggagat gagaaaaaaa ttggtaagga
    31141 ttttcctgga ttaattgaga tgatagtaga tactactatt tctttagatg aaaaagtttg
    31201 tagagaactt aaagatttta atccagattg cattgtatca gattcattaa gtttttgggg
    31261 aaagttattt gcacaaaaac ttaatattcc atatgtatgc tctacaacaa cttttgcatt
    31321 taataaacat acagcaaagt tgatgaaaca aaactttata gaaattatac gtatgatttt
    31381 tggtgtaaga cgcattaata aaaaaataaa gcttttacaa agaaaagggt atgaagtaaa
    31441 aaattttatt tctatagttt ctaatgataa tgatacggat accattgtat atacatcaaa
    31501 agaatttcaa ccaatggtag aaaccttctc tagtaagtat tcatttgtag gtccatcagt
    31561 atcaaagttg attattgaac ctaaagagag aaaaagaaag ctaatatata tttcgcttgg
    31621 tacaattaat aataaaaatg ttagctttta taaaaactgt ataaatgcat ttaaagattc
    31681 tgatgttgat gtgattatgt ctgttggtag aagtactaat attaaaagtt taggaaatat
    31741 accaaataat tttgaggtta aaaatagtgt tgaacagatt gctatacttc aaaaaactga
    31801 tgtgtttgtt actcattctg ggatgaatag tgttaatgaa agtttatatt atggagtacc
    31861 tatggtatta tttcctcaac attcggagca gagaatggta gctaagagag ttgttcattt
    31921 gggagcagga attatgttaa aagaggataa gtcagaaagt attaaaaaag cagtatttca
    31981 agttataaat gacaatgaat ataaagaaaa tgcaactaaa ctatcaaaaa gcttttataa
    32041 tgcaggaggc tcaaaaaaag cagcagatgt aatattacag attatatgta atagtagaca
    32101 agttgacata taatagattt gttaaaaata tatatacata catgtaattt aatcaaagta
    32161 ctgacagtgg ggtcttttaa cctaccagtt ggggcatata tattgatgct aaatatgagg
    32221 gatgttatat tttaataaaa aagataacat ccttttttta gtgcattata tcgagtttta
    32281 aataataaat gaaggaggat taatatgaaa aaatataaag ttatttttat agtattaatt
    32341 ataggtatta taagtgtaac agggtttgtt gtatataaaa actacattaa accatggaaa
    32401 gatgctgaaa catatattga taagtatatg gtaaagcaag atatttcaaa agataatata
    32461 aaaagtatta caaaagaaaa agccaagaag gcaagttacg aaggaatact atacaaagtg
    32521 tattacaaag gtgaccctcg atatgagtat caatattttt atagtgataa ttattatgct
    32581 ctatatgtaa ataaagtaat gttacaaatt tatgatatgg aaaataataa taaactttta
    32641 agaagtaatg aggaattaaa aagtgtaaag tatccaccaa tatatcttaa atataagcca
    32701 gataaatgat ttatgacaaa atagaatgat ttttattaaa atttatttaa aaatatcact
    32761 agagtgttta aataaaacta aatttaagta tttatatatt agtatatctt actagtgttt
    32821 aaataaaact aaatttaagt atttatatat tagtatatct tactagcatt taaatgaaac
    32881 taaatttgaa gctttaccta ttaatatatc ttaatagtga ttaaataaaa ctaaacttaa
    32941 gactttatat gttaatatat cttaagaatt tatttgttaa catacagttc attatattta
    33001 aaagcattac tatgataatt cataatagta aaatagataa tggttcagac aatattataa
    33061 atattagtga cggtaaaata gtatcaattt agtatataaa ccttgtcaga taatcgcata
    33121 acagagcttg tagttataga aaaaaaaaat atctaggaaa ccgttgacag atttatatgg
    33181 atagtataac atatagaata tgaaattaaa caaaaaagaa ttttaattat ggcgacgtag
    33241 tcataatttt gagtatgtta ctgattagca ggcagaactc aagtatatat gtgaaaaata
    33301 gagggatact ctatacatat atgcttgagt tctttttatt gaagggagga atatatgaaa
    33361 ataattcaga ttttaaataa taatgtagcc ttagtaaaaa gaggtaaaaa tgaaattatt
    33421 gtatttgtta aaggaattgg ctttaaaaaa agagtgggac aagtaataaa tgaaaatgaa
    33481 atagagagaa catatatact agattcatac gatatgctag aacactttag ttatctacta
    33541 caaaactcag actccaataa tatagttctt attaatgaaa taattgaata tggtgagaaa
    33601 gctttaaata taaagtcaag tgattatcta agcttaacct tactagacca tttagagttt
    33661 ttacttaaaa gatgtgaaaa gaatcaattt ataaaaagtc ctttggtatg gaatgttaaa
    33721 agattttatc caaagcattt tgaaattgga atgcatgcac taaaattaat tggtgatagt
    33781 aagggaatta atcttcctga tgatgaggca gtatcaatag cacttcattt tgtaaatatg
    33841 gaggtaaata aagagtctca tgatagtaca attgtagagt tgagaacttt agcagatata
    33901 gtttctataa taaaatatca ttttaatgta gagctagatg aaacttcaac aaattatatg
    33961 agatttacta ctcatctaca gtactttatc caaagaatta tgtcggatga agcttcaata
    34021 gatgaagata attctataga tttatataaa caagtaagtc aactttatcc aaagtcattt
    34081 ggaagtgttc aaaagataag aaaatatata aaatcacaat ttaatgtcga tatatctata
    34141 agtgaagaaa cttatttaat gttgcatata aatagggtga ctcaaagact ggaggcaaaa
    34201 tcagatgaaa tataaagatt taaatgaaaa tataataaaa cttatagggg gaaaagaaaa
    34261 tataaagtcg gtagcgcatt gtgttactcg tttaagattt actttaaatg ataggagtat
    34321 cgctcaaaca gaagaaatta aaaaattaaa aggagtaatt gatgtagttt ctaatgatgt
    34381 tgcttatcaa attataatag gtactcatgt tgtagatgta tataacgagt ttatgtctat
    34441 gataggttta agttcaagtg aatcaagtat aaaaagtgaa agaaaaaagg gaattagagg
    34501 tatcaaaggt atatttaatt ccatctttgt ggtagtctca gagactatga cttcagtaat
    34561 tgaagtacta cttgcagctg gtatacttgc aagtatatta gcacttttaa atatgtctgg
    34621 catacttcag agtgacagtc ctacatatca aatattagat acattaagaa gtgctacatt
    34681 tcacttctta ccagtattaa ttgcaatagc atcagcaaaa agacttaatg taaatcccta
    34741 tatagcagta gtgttagcag ttacgttatt atcttcatca atagatggtg tagaaggatt
    34801 aagtttattt ggtataaatt tacaggctac aacttatgca aacagtttta ttccaatact
    34861 tttaggagta tgggcaatgg gaattataat tgaaggtttg aaaaaaatat tacctaaagc
    34921 actacactat tttttagttc cagtattatc tttaataata actctatcag ttacattaac
    34981 tgtatttgga cctattggta tgtggattgg tgatggatta aactatgcat gtatgttttt
    35041 aattgataca ttgggtaatt ggagtgttgt tgcactgtat gcagctttac aaccactctt
    35101 aatagttttt ggtgcagcaa actttactat gcctatatct ttaaattctg tgacaacatt
    35161 ggggtatgac ccaattttta tgggcgctgc aacaatatct gatattgcag tttgtggtgc
    35221 aatgtttgga tatttcttaa aaactaggaa taaagaacaa aaacaactat ttggtacagt
    35281 aagttttagt gcacttatgg gagttacaga accttcagtg tttggtgtgt ttatgaaata
    35341 tagaagacca tttgtagcag taatgatagg tggaggtata ggtggtttaa tagcaggttt
    35401 agctcaagtt aaaacatatg gaatggtttg gggattagct gcattaccaa catatcttgt
    35461 tggaggagaa gtatctaact ttacatttat gataataagt gtagtagtat catttgtagc
    35521 agcaacagca gcttcctatt tactaggaat accttcagat gaaaaagaag aagttaaggg
    35581 tgataatgaa aaagaattag aactaataat caacgagaac aattcaagaa ctattagtat
    35641 tggaaatgtt gcaaaaggtc aggtaattgc acttggggaa gttaatgaca aagcattttc
    35701 atctggagca ttaggtaaag gggttggagt tatacctagt gaatcaaaat caactgttat
    35761 atctcctgta gatggaacta taactatagt atttccaact aaacatgcat atggtatagt
    35821 gactgatgaa ggattagaaa tattaattca tattgggata gatactgtaa acttagatgg
    35881 aaaattcttt gaaagtcttg taacacaaaa tcaaagggtt aaaaaaggag atgctttagc
    35941 agtatttgaa tctgataaaa ttatagagga aggctttgat tctactataa taactgtagt
    36001 tacaaatact agcgattatt tagatgtaat ctcatcaaat gatgaatcag aagaattatt
    36061 aactgtaata gtataaattt taggagggaa aattcatgaa tattaaagat acatttttct
    36121 ggggaggaag tattgcagcc catcaatgtg aaggttcatg ggatagtgat aacaaaggac
    36181 ctgcaattat ggattttgta actaagggct cttatgaaac gccaagagta attactgata
    36241 aaatagaaga aaaattggat tatccatctc ataatggaat agatttttat aatagatata
    36301 aagaagatat agctttattt aaagaaatgg gatttagtgc attaagaata tctatagatt
    36361 ggtcaagaat ttttccaaat ggagatgatg aaaatcctaa tgaattaggg attaaatact
    36421 atgaaggtct gatagataca ttaatagaaa ataatataga acctattgta acactatatc
    36481 attttgaatt acctatgaat ttagtacata aatatggttc atggaataac agaaaactta
    36541 tagatttgta tttaaagtac agtgagactg taataagaag atttgatgat aaggtaaagt
    36601 actgggttac atttaatgag atgaaccata ttgaccctca aacagagcac tcggatattt
    36661 ttacttatat gatagcaggt attaagtata gtgaaataga aaataaggtt caaacattgg
    36721 caaatgtagg gtataatatg actttggcgg gtgtaaaggt tgcaaagttg gctagagaaa
    36781 tcaatcccaa caataaagtt ggatgtgtat ttggactaaa tccaatttat ccatacaatt
    36841 gtaatcctag taatgtgtta aatgcatttt tagataatga ccgtgattat tatcaaattg
    36901 atgcaatgtg caatgggaag tttccacaat ataaattaaa agaatatgaa aaaaataata
    36961 taactattga agtgactgat gaagacaaaa aagcatttaa agaaggtaag ttagatttta
    37021 taggacttaa ttattatttt tcaagtgtat ctactccaaa agaaaattta tcaggtgata
    37081 aatctttatt tggtgggatt caaaatccat atttggaaca aagtaagtgg ggatgggcaa
    37141 tagaccctat aggtttaaga tttaccttga actatattta cagaaagtat caattaccta
    37201 tcttaattac agaaaatggt ttaggggcat atgataaaat cgaagaagat ggaactataa
    37261 atgatgatta tagaattgaa tatttaagta agcatctatc tcaaatgaag tctgcaattg
    37321 aagaggataa tgttgaatgt tttggatatt tgatgtgggg accaattgat ttagtcagtg
    37381 caactacagg tcagatgagt aagagatatg gatttatata tgttgactta gatgatgaag
    37441 gcaaaggaag ttttaagaga tataagaaaa aatcatttga ttggtacaaa gaagtaataa
    37501 aatctaatgg agaagtttta gatttttcta cggatatagt agtagggtag gaataagata
    37561 aatagaagtt aggaactaat gttaattagt gtctagtaaa gcatttaaaa tagagtatag
    37621 ggtctttaaa gtaaagtgtg tattcttctt aaaagtaatg gcaactaaaa ttactataaa
    37681 aaggagaata cacatttttt atgtttatac ttaagtaaat atttagacat attcatagta
    37741 taatttactc attatataaa aatagtatga tttactcact atataacttt ataaattttc
    37801 tggaaaaatg tcagaatata ttgacaaaga aaagatttaa aattataatc tatattaaga
    37861 atagtttgac aatataaaaa caagtatttt tataaatagt gaaattattt ttattgtaaa
    37921 tttaagaata atttaggact actataaaga taaaggtata gatgtcatta tatgataaat
    37981 catacttgta tagaaagaat tttaaagtat ggcttatcat tgatttaata taataaataa
    38041 tttttgtttc tagtaatagt tcctaggaat aagatatcta aattcgttta gaaatagtct
    38101 aatttacaaa ggaggggatg cactaataga taaaatttct atataaagaa gacttaaagt
    38161 gaagtatatt ctgataatat tggtttaatg ggtatattat tatttcgttt tagatatttt
    38221 aagaataatt taagacgttt ataaaaatgt attctatatc taatatttaa ataaatataa
    38281 gtcttccaac atgtatacta atatagagag tagttgaagt acaattctaa ctcgtaaaat
    38341 tatgtagaaa gtaaaaatca aaaagaaatc tagtaagttg ataactatag ttaatattta
    38401 gagagttaac tctagttata tttatttaga tattttagga ataatttagg acgtatataa
    38461 tatcatcaaa aaatatcaag ctataccata tgtagttaag aataactgca taatatacat
    38521 tttataatta ttgttttatt gataaaaaat tattatattt aggaggaaac aacaatggaa
    38581 aatttttgga atccacttac ttgctttact gtatgtgtaa tgatttatgc ttttagtgag
    38641 tttttatcta agaaaacaaa aggtgcaatt tcaacattgt tatttgtatg tattatattt
    38701 ttactaggat tttggacaaa tattttacca aaagacatta caggagcatc agggatatta
    38761 gctgcaatga gcaactttgg tatagcttta ttaataacta acttaggaac acttataaat
    38821 cttgaagact tatgtcatga atggaaaacg gttgtaattg cattagtagg tattgtagga
    38881 ataggggttg gctgtttaac agtgggtagt atgttatttg gtagagagta tgctttaata
    38941 gcagcacctc caatagcggg ttctactgtt gctggtatta tcgtaacaac tgttgcagaa
    39001 gctgcaaata gacctgaact tgctgcattt gtaattctag tattatcatt tcaaaagttc
    39061 tttggcattc cgataactac atattgtata aataaagaat taaaatttaa aagagataac
    39121 ggggattttt tgaaagatga gtcaaaaagt aattttaaac ttccaagtat gagaattttt
    39181 aaagaagatt taggtaaaaa atcatctact ttagtatatc ttgcaaagct ttcatttgtt
    39241 gctatgattg gtaattttgt aggattggct actttaatac caggatttac ccctgcaaac
    39301 tattatttaa atcccaacat agcatgtttg ttagtagggt tgatttttac acgaataggt
    39361 tttttagaaa aaggaatttt agataaatct caatctaatg gaattataat gtttggttgt
    39421 atgttgatgt tacctggagg acttgctaag gtaactccaa cagcattgtt tgggatgatt
    39481 attccaacta taggaatact tgttgtaggc tctgtattta taatactatt tactgcaatt
    39541 gtaggaaaac tattgggata ttctccaaga atgtcagctg caattggtgt aacttgtatg
    39601 ctagcttatc ctgcaacaca gataatttcc aatgaaggta ttgatgctat ggaaggaact
    39661 gaagaagaaa aacaaagggc aacagattat ttattaccaa agatgattat aggaggattt
    39721 gttactgtaa ccattgcatc agtggcattt gctagtataa taggtccaat tatatttggt
    39781 tgatagtaaa tagatttata ggaggaatag aaaatgatag gaagtatatc tataaatgag
    39841 atagataaaa aaagattcaa acttgatgat ttaagtaaga aaatatggga aaatccagaa
    39901 aaagcattta aagaatttaa agcatgtgaa aatacagcaa actttctaag aagtgaagga
    39961 tttgatgtgg aagtaggtgt aggaggttta gccacggcta ttagagctag ttttggttca
    40021 ggtaaaccag ttataggttt tatgggagaa tttgatgcat tacctggttt aaatcaaaaa
    40081 gtttcaacaa aacaagaagc atttgaattg ggtgcatatg gtcatggatg tgggcataat
    40141 ttattatgta cagcacatgt aggggcagta gtagggctta aaagagagat gatagaaaat
    40201 aacttaagtg ggactatagt attttatgca tgtccaggag aagaacaatt aacaggtaaa
    40261 ggatttatgg ctagaggtgg agcgtttgaa gggttagact tagctataaa ttttcatcca
    40321 aataaaatta gtgaagctac aattggtact tcaacagctg ttaactctgt aaagtttcac
    40381 tttaagggaa agactgcaca tgcaggctca gaccctcaaa atggaagaag tgcactagat
    40441 gctgtggaac ttactaatgt gggagctaat tatttgagag aacatgttac ttctgatgta
    40501 aggattcatt atacaattac agatggagga gtagcaccca acatagttcc tgataaagca
    40561 tcagtatggt attatacaag agctttaagt agagaagctg tagaaagtac atatgaaaga
    40621 cttgtaaagg tagcaaaagg agctgcaatg atgactgaaa ctgaagttga agtagaattt
    40681 ttaggaggat gttataatac tttaaacaat catgttttag caaatcttgt atcagaatgt
    40741 atgaatgaga ttaaacaaga gccttggact cgagaggaat tggattttgc agctgaatta
    40801 gatagacaaa gcccacaaca atataaggct atgataagta aatataattt gccagaagga
    40861 actcatctat attatggtgg aggaaatgtt acaaacttta atagttatgg ctctactgat
    40921 attggagatg taatgcatat agttccgaca gcatactttt ttacagggtg tacgaatcta
    40981 ggtgcaccag gtcatagctg gcagtttaca tcttgtgcag gaagttctat aggagaaaaa
    41041 ggtatgatat atgcatcaaa aattatggct atgtttggag ctaaaatatt aaataatcca
    41101 gagatagcta aaaaggcaaa agaagaattt gataaatcta tgaatggtaa aacatataaa
    41161 tgtcctattc cagatgatat tccaactcct taaaaagaca tgaagtttaa tatataaaat
    41221 tataattttt atatcagcat catttcatta ctaaaagaaa gtgagatttt gctgactatc
    41281 tgattaggag gaaggaatat gaaaaatttt tttaaagaag cgcagtcaat agaaggggaa
    41341 attattagat ggagaaggta tttacatgaa aatcccgaaa ttggttgcaa tctaccgaaa
    41401 acagtaacct ttgttaccag tactttagaa aaaatgggat attctccgaa attgacgtct
    41461 aataatggaa tagtagctgt tttagacagt gaaaatggtg gaaagacctt attattaagg
    41521 gcagatatgg atgcacttcc tattatggag gagacggatt taccttttaa aagtaagaat
    41581 aaagatgcat ctcatagttg tggacacgat aatcacacag caatgctctt aggagcagct
    41641 aaaatactta tggataataa gcacttactt aaaggtagag taaagtttgt atttgaacca
    41701 gatgaagaga ctaccagagg tgcaaaatca atgattgatg atggtatatt agaaaatcct
    41761 caggtcgatg cagctatggc atttcacagt atggtgggta aatttcttaa cacaggtcaa
    41821 gtagcttatt cacgtggtcc agctatggca tctgcggata tatttgaaat aacagtagaa
    41881 ggaaaagcaa ctcatggagc aagccctgaa tttggagtgg acccaataaa cataatgtcg
    41941 catatacaaa tagcattaaa cactatactt tcaagagaaa aacctcagaa agaacctgta
    42001 gttttaacta ttggtatgtt taatgcagga aacgtaccaa atgctatacc aaataaagca
    42061 tctatgtcag gaactttaag aacatttgac caatttgtta gagaaaaatt aaaaaataga
    42121 attattgaaa tatctacagg aatagctaaa tcatttggag gaaatgctaa agtggaattt
    42181 aaaatgggga ctcctgcagt tataaatgat ttggatgtag gagatgagat tgtatcttat
    42241 gttaaagaag ttataggaaa tgaaaatgta atagactttc catctgcaat gggttcagaa
    42301 gatttttcag agattttact aagggttcca ggagtatttt tatggattgg aatgggaagt
    42361 attagtcagg gatataattt tggtatgcat aatcctaaag caatttttaa tgaagaggga
    42421 ttagtttatg gttcagcttt atttgctcat tgtgcagtaa aatggttaga aaataatttt
    42481 agtagataat aacataaaat attattaaat atcataaaag gtatatctta aaaagatgca
    42541 aagatatacc ttttagaaag tcatatataa ttttacttaa tattagatga taaaatattt
    42601 ttatgcattt tggattttaa tatttatttt ctgatataaa taatttgtat accctttcag
    42661 gtctaccttt tgttgagttt tgtttttcat ataatatagt agcgtttcca gactttaaga
    42721 gactacttag aaatctatta gcagttctaa ctgttacatt taaacatgaa gataattcct
    42781 taggagtaac ttcatctctt tgtagaattt cagtaacaga tataatcttt tgaatagtaa
    42841 gagtagacaa tttagaactt ttggcaattg tatttatatg tggagttact ttatttgaaa
    42901 cagtaagtaa cttatcacac agtaaaggtc ctattgtctc ataattttcg ttaactaaga
    42961 aactgtaatt taaaggattt attttagatt ccttattagc acttatggca ctagacatag
    43021 cttgctttat atcattacca attccatatc caacacatac tttaatattt gtactatttt
    43081 caatagattc ttttatataa catgcagtaa aatttttagt taatgattta atcgtttcac
    43141 atttagtgaa aattttaaaa gaattactat ttttttcaat tataaaatcg gttaatttat
    43201 cttttttaat actatttaat attttataaa cttggtctag agtagagtca tcataatttg
    43261 tatctttaac tgttatatat attacacttg gttgatttcc cttcattcta tgtaaatgaa
    43321 tatcttttat taagttatta aaagtatttt ttaataaatc tatatcaggg tatatgaaat
    43381 gaaagtttac tcctgcattt tgtaacatag gaacaatact actaaaacga gtagtagaaa
    43441 aatcgatttt cccttcattc catagattaa tatgtttttt tgcaatcttt ttttcaagtt
    43501 ttgctatgtc agataaactc attttagatg cattttcatc aatactatcc attaagtctc
    43561 caaatgtgcc atttgataaa taatatgata tatcttttgg attatctgcc cagtctgtta
    43621 agtcaaagta tgctctggaa aaatctaatg tattatattt aaagataagc tttagaaaca
    43681 tatcatagta actttgtaag tcagtaccaa aatcaactag aggttttttt atagttccag
    43741 ccttttttgt aatagctttt ttggggatag ggccactaac tgcaaatcca tcaaacctat
    43801 cttctatttc taaatataaa tctccaacat gagaaaaatc tctatagata tatattttaa
    43861 tttctgcatt aatatttaac ttttttatag aattatctac aaactctttt aaaaattcgg
    43921 ttgttatgac tgctattttc atcatagatt acttcctttt caattattat aattatttta
    43981 tattaaatat tacattaatc tattgttcta gttaaaatcg tatttcaatt aaattcaatt
    44041 aaaataaata actctttata aaaagcaatt atttaggtag aggaatattt gctaacttta
    44101 atagtctttg ttaactttaa ttttatttaa gttattatag tcttactaat tttataattg
    44161 tagacttaac tactttatgt tcttttattg tttatgtagt tgatttagaa gttattttaa
    44221 ccatttattt taattgaagt tgtttgattt ttaaatcctt tgtgtaatct ttgtttttct
    44281 agccatgata aaagtatttc tatttgtatc actatatata ataatatcat gacaaaatat
    44341 ttattgtcta actaattata atctatccaa aatgaaaatg ggtgtgagat attattacaa
    44401 caaattgtat tagtattaaa aagattaaaa aattaaaaaa ctaaacagtt aaataattaa
    44461 acgattaagt gactgtcata taacaattta taattttatt taacagccac ttaggtattt
    44521 aagagcgata gaattgagtg tatatcaaat tataataatt tcctagtaaa taattgaaaa
    44581 ataaggtagt ccatttttat atttgatatc tggtttacct tgaataagtg gatatagata
    44641 atttagggct tcatcagtta tataattaca ttcttcattt atccactctt taggaaaata
    44701 ttttgtcttg ttagctattt tagaaatatc agtatgacta acttcatact tataaggatt
    44761 attgcatgtt ctattaatga tagccataac tcctgtatat ccttttttag atagttctat
    44821 cccatatgca ccaacttcag ctgcttgttt taaatcagta tatgaagcta aatgcatagc
    44881 acatctttgt attacaccaa gttctaaggt ttttactctt gttgtaattg atgatgatac
    44941 tataagattc tttagatagt tgcttactcc acctaattgg gaatgaccaa atttatcatg
    45001 agcagaagtt ttttgttcgc atataaagtt gccgtattta tcccttatac cttctgatgc
    45061 aactatataa gccttatttt tttctttaaa tatttttcta acatcttcta taaacttatc
    45121 ttcatagaaa tcaatttctg gaaggtatat taaatcaaca agtggagtat cattaagtct
    45181 agctagtgaa gaagaagctg ctaaccatcc agtatctcta cccatagttt ctactataaa
    45241 tataccatta tttttgtata tagaaaaatc taagtatgtt tccattatta gtgtagaaat
    45301 aagctttgca gcagaaccaa atccaggaca gttgtcagtt cctaataaat cattatctat
    45361 tgttttagga atacctataa attttatttt acaagtagtg tttttgcagt attgagaaaa
    45421 tttcatcact gtgtccatag aatcatttcc gcctatataa aataatgtat ctatttcata
    45481 ttcatctagt atatttataa ccctatcata atcataagaa tttattttat aatcagccag
    45541 tttgtatcta caagaaccaa gaccagacga aggtgtttgc tttaaattta atacattatc
    45601 tttgtttaag gagtctgaat ctattatatt tttgtttaat ataccttcaa tcccattgat
    45661 accaaaatat actttatcaa agtatttagt ttctaaattt ttttcataaa taccaactgc
    45721 agaagcattg ataacagctg tagggcctcc agattgggca ataatacagt ttctcatttt
    45781 acatctccct ttcattaata ttgttatgaa tggtactttt tatcgagtaa atttatattt
    45841 atagtctgat tatatattaa atgaactagc tatatcaatt gagttagtat agacaataaa
    45901 tgccataaga atgtggtaaa aaactaactt tttatataca attaatgtct ataatttacc
    45961 acaatataaa ggtactttta aggagtagtc aaagtgttgt gaaaaaaaat atatcagtgt
    46021 aatattaatt tacaaagcaa aataagttca cagttaacaa aagcagaata agttcataaa
    46081 agaaatatat acagcaataa aagtaatgct aaataaaagt aatactggat taaaaaatat
    46141 taaaaaaata tcaaaaacta atatttaata ctaattaaag taaaatatgg aggtatacaa
    46201 atatgaaaca cataaaaata gcagcaggat tagcacatgt aaattacggt catatatcag
    46261 ccgtagttaa agaagcaatg gatgcaggtg tagactacgt acattcagat gcagcagata
    46321 tgcatgactt aaaaaatatg caacttatgg gtggtcatca aataatagaa gcaataagac
    46381 cagtgacaga taaaccaata gaatgccata tatacacaag agattgtgat agattattta
    46441 tagaaaaaat agcagcagca ggatgtaact tgttgataat accagcagaa cattttttag
    46501 gtgctcctct tgcatacata ataaattact gtagagaatt tggtatgaaa gtaggattaa
    46561 caattggatg ttacacacca ttatgttttg ttgatgaagc tatatatgat atagatagat
    46621 tgcaaatagt cgttcatggt gttgatgaaa ctgatggaaa agataactgg ggatggagaa
    46681 agagtgctgt tgatttagta aaaagagcta gaaaaatgat agacgaaaag aatcctaagt
    46741 gtgaattagc aatagatggt ggactaagag cagacaatat ggagccatta atagaatgta
    46801 atccagacgt tgtaatatta tcttcagcaa tattcaagga taaagatggt ataacagcag
    46861 gtgttaagaa ttgtagaaaa gctatagatg aagcagctac aaagtttggt ttagaataag
    46921 ataataaact atgataaaag agatgctttc ttaatgtttt aaggaagcat taattttatg
    46981 aaaaactaca ggaagctaga ctaatttaat tgatttttta tactgaaaca atataatcat
    47041 aggaggttat taaatgaaaa aagaaatgat aaaagattat ttactgataa caatatcagc
    47101 atttttaatg gcattagcag ttaatttttt ctttgcagaa catacattag ctccaggagg
    47161 gataacagga ttatcagtcg tacttagcac attcttatca atgcctgttg agaatatatc
    47221 attaggaata tctatgccac ttttagtaat gggattatta tttttaggga aaggttttgg
    47281 aataaaaaca ttatatataa ctcttatggg cccattattc ttaaaagtaa taccacaaac
    47341 tcacataact gacaatctat tagtagcagg agtgataggt gggttattgg taggaactgc
    47401 tatagggata gcaataataa ggggctgtag tactggtgga actgatttag ttgcaatgct
    47461 tattaataag gtaattaagt ttctgaagtt gccagttata ttatttatgc tagatggatt
    47521 tataatagta gcgtctggaa taataagtaa gaattttatg atatctatat attcattgat
    47581 atctttatta ctcataataa aaacaatagg atttgtaact acaaagtttg gtaagaatac
    47641 tgaagaaatt aataatataa ataatgcttg tgctcaataa aaataataaa atttacttta
    47701 aatataaaag tttaaaaaat ataaaagctt aaataaaaag attaaatata aaaaatgaag
    47761 gtgtctcaaa atgaattttt tagttcatga ggcacttttt ctatgaaatc aaatatattt
    47821 ttatcatttg gacaatgaaa aataggttta tctctatgtt gagacaagcc tatttttgtt
    47881 tatttataag ataatatttt atttttttca gaatatagtt tttttataat tgtactaagt
    47941 ctagaaatat cattcttact taaaagagca tttatattta tcagttcagc attatgttca
    48001 aagtctacag gagcagtagt tagtattaag tccacatcat caaagttcgt aaatgaaata
    48061 gaagatagag gtatagattt aactatatta atctgattaa attcaaaact taacttttgg
    48121 actaataaat tagatacacc atcactacag tgacatatta aaatagtatt taggggagat
    48181 ttgcttctat ctattgctga tattaaatat aaagcaagat atcctatttc gtcatcattg
    48241 acttcataat tcatcaactg tttgataaca gtattagact ctttagcagc cttataagta
    48301 taaggaaatg ttctctttat atcatttaat atgggatttg taatagtaaa cccatagttt
    48361 attctgtgta gaactgattt aaggtgatta gcaagagact ttattaatat taaatcatcc
    48421 tttaagttta agtttagtat acttccccaa tgaacagcta ttgcttcaga tagattatac
    48481 tctgtaattt cttcattttt aagaggttca agagtagtag ttttctttat tgatttaagt
    48541 aatccttcta tatgaagaag gatataacag acctcttcat caataaattc tacgtcaaaa
    48601 gcttcactta ggttagcaca taaaattttt gatttttcaa agtattcatg ttctaataat
    48661 tctctaaaaa aaccttcaga taagttaata tatcttttaa ttgaaattct tttaatacat
    48721 atagctatat gtattaagaa gtttatataa tactcatcac taaggttact tttttctact
    48781 tgtaaggtgt gtagagtgat ttgagataat ttctcaaaat catagttaaa tagttcctta
    48841 aatatttttg ttgatggggt atctttacat tcattagatt tcgagaataa tatttcttta
    48901 agttcagtat aacttttatt aaccgtagca agttcaaaaa ttgcttttcg aatatctttc
    48961 tcttttccct ctaaatatac tccattattg gtttttctaa ctagagtcac tttaaagttt
    49021 tgcaaaaaat tttgaataac taccaagtct ttatgcacag tagctctact aacatgtagt
    49081 tcattgcaaa tatcacgaat cctaaactta gaatttttaa taaataattt acttagaata
    49141 tacctttttc tatcttcagg agagtatgca tatatacaat ttgatttatc attgatatct
    49201 ctaataactt taagttttat atcttcatta cctagaataa taacccctga accagttttt
    49261 ttatctaggg ataaattaaa ctctaaaagc cattcatcta aaataacaag gtcattacga
    49321 atagttttat tactaacttt taattcttcg gcaatagtat ctacagtaat atagtctgag
    49381 ctgttgagta ataattcagc aatatctaat aatcttttgt tcaatgcaaa
//
LOCUS       DAEOTL010000020        49013 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEOTL010000020 DAEOTL010000000
VERSION     DAEOTL010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49013
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.020"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(43..555)
                     /locus_tag="KRH82_001466"
     CDS             complement(43..555)
                     /locus_tag="KRH82_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654753.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            1108..1992
                     /locus_tag="KRH82_001467"
     CDS             1108..1992
                     /locus_tag="KRH82_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBG8654754.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNNKLIYSNMIDK
                     KTQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVP
                     YNLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNK
                     DAKFSTKDVEKFINFFSAIPAKDTDDTIKISEQIKNEWKKRKISFKNNKNISIINGFL
                     RYPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKMSE
                     GEIELPDPIIMENDKLMK"
     gene            complement(2305..3084)
                     /gene="hisJ"
                     /locus_tag="KRH82_001468"
     CDS             complement(2305..3084)
                     /gene="hisJ"
                     /locus_tag="KRH82_001468"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBG8654755.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(3654..4004)
                     /locus_tag="KRH82_001469"
     CDS             complement(3654..4004)
                     /locus_tag="KRH82_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBG8654756.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(4020..4436)
                     /locus_tag="KRH82_001470"
     CDS             complement(4020..4436)
                     /locus_tag="KRH82_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBG8654757.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(4455..4646)
                     /locus_tag="KRH82_001471"
     CDS             complement(4455..4646)
                     /locus_tag="KRH82_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBG8654758.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(4797..5612)
                     /locus_tag="KRH82_001472"
     CDS             complement(4797..5612)
                     /locus_tag="KRH82_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBG8654759.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(5659..6597)
                     /locus_tag="KRH82_001473"
     CDS             complement(5659..6597)
                     /locus_tag="KRH82_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8654760.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGRIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVMISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(6594..7466)
                     /locus_tag="KRH82_001474"
     CDS             complement(6594..7466)
                     /locus_tag="KRH82_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8654761.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(7491..9419)
                     /locus_tag="KRH82_001475"
     CDS             complement(7491..9419)
                     /locus_tag="KRH82_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBG8654762.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(9531..9908)
                     /gene="gcvH"
                     /locus_tag="KRH82_001476"
     CDS             complement(9531..9908)
                     /gene="gcvH"
                     /locus_tag="KRH82_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBG8654763.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(9995..12121)
                     /gene="cdhC"
                     /locus_tag="KRH82_001477"
     CDS             complement(9995..12121)
                     /gene="cdhC"
                     /locus_tag="KRH82_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBG8654764.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(12178..12984)
                     /locus_tag="KRH82_001478"
     CDS             complement(12178..12984)
                     /locus_tag="KRH82_001478"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBG8654765.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(13034..14401)
                     /locus_tag="KRH82_001479"
     CDS             complement(13034..14401)
                     /locus_tag="KRH82_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBG8654766.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASEAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(14432..15376)
                     /locus_tag="KRH82_001480"
     CDS             complement(14432..15376)
                     /locus_tag="KRH82_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBG8654767.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(15396..16166)
                     /locus_tag="KRH82_001481"
     CDS             complement(15396..16166)
                     /locus_tag="KRH82_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8654768.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(16222..17607)
                     /gene="lpdA"
                     /locus_tag="KRH82_001482"
     CDS             complement(16222..17607)
                     /gene="lpdA"
                     /locus_tag="KRH82_001482"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBG8654769.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(17651..18532)
                     /locus_tag="KRH82_001483"
     CDS             complement(17651..18532)
                     /locus_tag="KRH82_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBG8654770.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(18568..19242)
                     /locus_tag="KRH82_001484"
     CDS             complement(18568..19242)
                     /locus_tag="KRH82_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBG8654771.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(19279..20151)
                     /locus_tag="KRH82_001485"
     CDS             complement(19279..20151)
                     /locus_tag="KRH82_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBG8654772.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(20243..20875)
                     /locus_tag="KRH82_001486"
     CDS             complement(20243..20875)
                     /locus_tag="KRH82_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBG8654773.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(20980..22656)
                     /locus_tag="KRH82_001487"
     CDS             complement(20980..22656)
                     /locus_tag="KRH82_001487"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBG8654774.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(22905..23684)
                     /locus_tag="KRH82_001488"
     CDS             complement(22905..23684)
                     /locus_tag="KRH82_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8654775.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASLGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(23994..25913)
                     /gene="cooS"
                     /locus_tag="KRH82_001489"
     CDS             complement(23994..25913)
                     /gene="cooS"
                     /locus_tag="KRH82_001489"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBG8654776.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(26520..27431)
                     /locus_tag="KRH82_001490"
     CDS             complement(26520..27431)
                     /locus_tag="KRH82_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBG8654777.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(27547..28125)
                     /locus_tag="KRH82_001491"
     CDS             complement(27547..28125)
                     /locus_tag="KRH82_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBG8654778.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            28351..29274
                     /locus_tag="KRH82_001492"
     CDS             28351..29274
                     /locus_tag="KRH82_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8654779.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQGSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(29446..30588)
                     /locus_tag="KRH82_001493"
     CDS             complement(29446..30588)
                     /locus_tag="KRH82_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBG8654780.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMDEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(30606..32360)
                     /locus_tag="KRH82_001494"
     CDS             complement(30606..32360)
                     /locus_tag="KRH82_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBG8654781.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKQSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            32496..32702
                     /locus_tag="KRH82_001495"
     CDS             32496..32702
                     /locus_tag="KRH82_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654782.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(32707..33630)
                     /locus_tag="KRH82_001496"
     CDS             complement(32707..33630)
                     /locus_tag="KRH82_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654783.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKTIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIVDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(33884..35584)
                     /locus_tag="KRH82_001497"
     CDS             complement(33884..35584)
                     /locus_tag="KRH82_001497"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBG8654784.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(35996..36409)
                     /locus_tag="KRH82_001498"
     CDS             complement(35996..36409)
                     /locus_tag="KRH82_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBG8654785.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(36475..38853)
                     /locus_tag="KRH82_001499"
     CDS             complement(36475..38853)
                     /locus_tag="KRH82_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBG8654786.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            39172..40623
                     /locus_tag="KRH82_001500"
     CDS             39172..40623
                     /locus_tag="KRH82_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBG8654787.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(40827..43340)
                     /locus_tag="KRH82_001501"
     CDS             complement(40827..43340)
                     /locus_tag="KRH82_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBG8654788.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGDINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNNYGVANTVLQALYENTDIDNIMSSQDVKKIRIAVI
                     ENSDTRLKELDEYCKMNLMSPELVYCKTNDEQLEALKSGKADVLLNVSMNPLEGVRTV
                     AKFSSKPFYFITPKGSTNLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETDYIKETEKLKVGVLLNKPPFQNIDKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLENMTKKREIDIVAGMIYDYEYSREHNIVMSRPFLSTQYTMMINNKLNENSLDGK
                     RVALAKGINYYGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRKEYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLLGDKVLIDV
                     AKVLDESFAKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(43563..44384)
                     /locus_tag="KRH82_001502"
     CDS             complement(43563..44384)
                     /locus_tag="KRH82_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8654789.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(44902..45378)
                     /locus_tag="KRH82_001503"
     CDS             complement(44902..45378)
                     /locus_tag="KRH82_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBG8654790.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(45412..45990)
                     /locus_tag="KRH82_001504"
     CDS             complement(45412..45990)
                     /locus_tag="KRH82_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBG8654791.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(46094..48694)
                     /locus_tag="KRH82_001505"
     CDS             complement(46094..48694)
                     /locus_tag="KRH82_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBG8654792.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLDTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTNKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
BASE COUNT        15043 a         9347 c         5462 g        19161 t
ORIGIN      
        1 aacacaatta ccttttcatt caatcaaagt aatctttaag cattattttt caagctcatc
       61 aaagtaatta tatacgataa cctcacctgt ctctttatct gtagtcttta taatgccctt
      121 agctccattt acctcttctt ttgtaaattc atcatctagc acaactttga atttatcttc
      181 ctttccataa ccttgttgaa attcatctct caaaattgca tttttttctg cttttggctt
      241 caactcaaat tcaattccag atttcatttc atcaaaataa tttaatacta caacctcatt
      301 attcatttta ttagttgtct ttataatccc tttagctcca tttacttctt cttttgtaaa
      361 ttcatcatcc aatgttatat taaatttgtc ttcttttcca tattcctctt gaaaatccct
      421 cttcatttca ttgtatttag tttcaaactc tttactcttg tttaattcca tagctgatac
      481 atttgtcaat gatgctccaa ttgccattac tgttaatgcc attactatac cacttttaaa
      541 tttttttact ttcatatctt acctcctaaa ttaaatgttc tcaatgaaat tatataaaga
      601 aaatcctaag ttttacagtt tcattcttgt aactaaaatt actattatgt aaccaaactt
      661 tttgcttcaa ctattcctta aaagttgctt ttttgaggaa tagttgaagt taaataatta
      721 gattttatct atatttatag atttaaaatc aaatttatcc atataaataa atacttattt
      781 ttgcaaaata aaaattttta attactccaa tccttcttat ttacttaaaa tcctatgata
      841 agaaatttaa aagtctttac cttctttaac aataatttat ttacttttaa catacaaaat
      901 atagagagta tatcaaaatc attttactga atattctaaa aataagtacc ccctattagt
      961 atatatattt acatattaaa aaaaagtttt aaataaagtt atatttttta caacagtttt
     1021 gtaattaaaa acatattgaa ggtaaattta aaggtactat atactataaa tatgtcgaca
     1081 caataaattt aaaaaggaga actaaatatg aaaaaaagat taataataat gatattgtct
     1141 gttgtcttag tactatcaag tatacttacg atatttgcat attcaaatat taaatataat
     1201 aataataata aattgatata ttctaatatg atagataaaa aaactcaaaa tagtgtaaag
     1261 gaaatcctaa aagaaaataa aattaatgaa aaagacatag atacatttat taaagcagtc
     1321 aacaattata ataaattgca agttaaaata cttcaaaata atataaatat atctaaatct
     1381 ggatattctt caatcaatgc aaaacaagtt ccatataacc tagaaaaatt gcaagataat
     1441 tgggtgaaaa aattccctga ttatatggat gtaaattgta gaataactgc ttttagactt
     1501 tttaaagatt ttataaattc aaataagaaa tttactggag actctattga cttgaatgtc
     1561 gacttggaca ctataatgaa taataaagat gctaaattta gcaccaaaga tgtagaaaaa
     1621 tttatcaact tcttttctgc aataccagct aaagatacag atgatacaat caaaatttca
     1681 gaacaaataa aaaatgaatg gaaaaaaaga aaaatatctt ttaaaaataa taaaaatata
     1741 tctattataa atggatttct tcgttatcca gaaactaaaa acgtatttat aggtcataca
     1801 ggcatatgca ttaaaactaa aaatggcatt ctatttttag aaaaatatgg tgttacatca
     1861 ccttatcaag ttactaaatt taaaaataaa gaagatgtaa aaaattatat gtttaataga
     1921 ttgaagatgt cagaaggtga aattgaatta cctgacccta taataatgga aaacgataaa
     1981 cttatgaaat aataacttta aacgcaaaat agtatttata attactaagt caatataata
     2041 gagaaggtct atagatttgt gtaaatacaa gcttatctac aatcttatat aagaatgttt
     2101 atataaataa gatagattaa tcctaagtcc tattattcta ttgaatttta ttattatttt
     2161 atttagattc tattgttatt ttacttagaa cttattatta ttttatttaa gttctattac
     2221 tattttcaat catataaatt tacaaaagac tgtacataaa tttattttat acaaacttat
     2281 ctacagtctt ttgtgtgaat atatctaaat aatatcgtat ttatttattt cctctgcaca
     2341 gtgagaatca gaacctaaaa ctaatggaat atcgtatttt tttaccaact ctaataagta
     2401 tccatctata taaggctctt tgcagtactc ttttctattt ccagaaacat tataatcaag
     2461 ttcataacct ttttctttaa ttaactttat taactcttca agaattgtat ttcctttata
     2521 atcgtatgga aatacctgat taaactttct aactaaattt aaatgaccta ttctttttgg
     2581 tttatgtata cctaaatctg aatttacagc ttttatcaat gtttcataat acttattata
     2641 aacagcttca atacttccta atttgtcgat taaattttga aactcctcta cactgtaatc
     2701 tacacaataa taatcatcat caatcttaat tatatgtact gataaaagag aatcctctaa
     2761 ttcctttcca tatttattta aattctcctt tatcccttct tcgtatcctt ctataaaatc
     2821 cacttccgac ccaacattta tcttgatttt accctcatac ttttctttca acttcttgac
     2881 atcattaaaa tactttggta aatcttcaat actcatacaa ctatcatttt caggagcagg
     2941 gtctctaaat ccatttgcat acggaaaatg ttctgtaaat gtcatttctg ttattccaac
     3001 atccattgct ctttgtacat atttttcaaa atcatcctta cttccatgag gacaataagg
     3061 tgaatgtata tgaccatctt tcataaataa ttcactcctt ttttaaagaa aaaatctaat
     3121 ataaatgcat aaatctttta acttcaaaat aatattttta atcatgctaa tttttattat
     3181 atctaatatt agagtaattt taaactgcct tttaagtatc ttatcattag tactattttc
     3241 aacttaacat taatattatt ttttaactta acattaatat tattttttaa cttaacatta
     3301 atactatctt taaatagtaa tactcaatat ataattactt aacataaaat aactcaaatt
     3361 gcttgatgag gcttttgcag tatttaaaga atatataatt atttaacatt aaataatcca
     3421 atcttgtaat aaaatttact cattaaagta tattacagaa aatacctcaa aataaacttt
     3481 ttagttcatg agatactctt ttttacatga aattagatat atttttatca tttcaacaat
     3541 gaaagggagg cttatatcca tctttagaca accccttaga taaaattttt aataattaaa
     3601 catcacaaaa tataaaaatc gcttatatca aacgtataag cgattaatta tatttacata
     3661 tgttttttag cctctaacaa cattttatta gcttcttcca tatactctat agccttttca
     3721 atactctttg ctgtttcttc ttttccaata gctctagcct tttcaaccca ctctctaaat
     3781 ccttcttcat gagtttcatt gtgatttatc caatgtacta aaagtatttt taaagttttt
     3841 tcatccttag actctgatga ttcctcatga ctatgttcgt ggtcgtggtc gtgagcatgg
     3901 tcatgtggat gttcatgaca tatatctcca tgagtatgtt cgtggcagtg gtcatggtca
     3961 tgatgtccat gatgatatct tacaatctct ttatcaaaaa tcattagtta ttccccctgt
     4021 tattttatat taaactcttt ttttataagg tttacagaat cttttacaag tagtgctaat
     4081 ggtttacctt ctaatccaac taactccaca ttttctggca taataggtaa aagtatctta
     4141 agtgcctcac tgtctgcaat agcttcactt atattacaag taacttctcc catcatagaa
     4201 ttaggtatta ttacagaaat aggtgcaact attatatttg cttttttagc tgatactact
     4261 atagcatttt cccctgtagc tcctttatta gcatgagctt tcatcataga actagttgct
     4321 atagaattag tccctagtgc ataaatttct acatatgtag gtaactcttc tctcaaagaa
     4381 gaaactatct gggctccaat acctccaccc attccatcta tcactgctat tatcatatga
     4441 aattccccta ttaattaatt ttcttgtatt attatcttat ggtccatcaa tcttatttct
     4501 ttaattatcc catctattat cttttgctct cctaataaat ccgttaaata aatctttcca
     4561 tcacaagggt ctatattaac cacattttcc ataacctttt ctaactcatt attactttta
     4621 caaatgaaag ctgatgattc acacatataa atctcctcct aatatgattt ttattaaaaa
     4681 tcaaaaaaag attcccttag gtatttcaat aaaccaaaga aaccttcatg atttcagttt
     4741 ttgtatatta ttatacctta agtatatcac tttaatttat gtaaagtcaa ttaaagttaa
     4801 cgctttttat tatactcttc attcttgtat ttttcatata gttctttaac taattgcttc
     4861 tcataatcag tcaaatctcc ctccacaaac tcaacattaa attgttcagc taatcccttt
     4921 actatgtttt tctgtagaat atctatgtct atttttctgc caatttcatt ttctattcca
     4981 cttgcttttt tagctgtaaa tttcatagct ctttctttca attctggcgt cttagttttt
     5041 attaatttaa acaatttttc tacatcaaaa tccagtatta ttgaaccatg ttgtaataaa
     5101 acaccatctt ttctgctttg agcacttcca attaccttct tattattaat agtaacttca
     5161 tatgatgcat gtgcattaaa acatgcagct gataaatttt ccctacttat tctctcgcct
     5221 ctatttaaat tatctgtttc tataccactt agattcaatc ctttaactag accttcactt
     5281 atatatctat aagataggtt gatgctctta tcgattaaag gattatcttc tcctataatt
     5341 atactatagg ttagctcatt atcatgtaat acagctcttc cacctgtaat tcttctagta
     5401 tagtctatat tcatacatct acacttatct aaatctatct catcttccaa tttctgaaaa
     5461 tatcctatac tcaaacaagc tggttcccat gtataaaatc taagagttgg cttattatgt
     5521 cctttcttat atgcagtaaa tatagcttcg tcaattgcca tattcattgc tccttcatat
     5581 gatttattat gtataactct ccactgattc atgattatta cgcccccatt tttagtataa
     5641 atatatccta gaaatcctct atagatttat ttctcttatt gctaaatcta tctcactttg
     5701 atttaaaggt cttgaatagt tgtatatagt acttcctggt ctttcattat agtatggtct
     5761 attacaatcc ttacaacctc ttatttcaaa aggatagcct ttgtttatgt cttttaaaat
     5821 atcattgtca agctttatac tatttaagta tccattttta aacttaaaat actcttttgg
     5881 ataaccttta tttatcatat aagacattaa ctgtaccctt ctataacttt ctatgcttgg
     5941 ttgacttatc ttttccattt tagttcctct aactggagta aatgcaaata aactaatcat
     6001 tacatcattt tcctttaaat aagtatataa attgtatata tcttcatgac tttcacccat
     6061 accaactatt atatgtgtac ttattttatt gggatatgat tttgacattt cagttataaa
     6121 ttttaacttt tcatcatagt tatttccttt tattttttca tatagttctt tatttgctgc
     6181 atctattgct attcctattt tatcaactcc tactgaaaaa aacttcttta tctgttcatc
     6241 attttctaat tttgcagata gtgaaattgg catgtctatc ctaccactta tatagtttat
     6301 aaagtctaaa acagagttat gtgcttcttc acttgccatt gattgaatac atattctctt
     6361 tatatttttt cctttataag cttttaaagc atctaatatt tcttcttttg aaaactctgg
     6421 ccaaattact cttgataatt tatcttttct agtactactt tctattgatt gagaacaaaa
     6481 actgcattta tttatgcatt tttctccaat cattatatat gctgtggtag gaggtatatc
     6541 gctttttttg tttaatatcc caagttctat tgctgtccca actgatagtc taatcataaa
     6601 acgcaacact ccttacactc atttattgtc atattcattt ctatagcctt attctttgca
     6661 gaccttgatg gtaatactat tctattgact ccacacatta tagataattg gtctagctct
     6721 tttctataca ctcctcttgg tctcatacaa cctagattaa tttcagtatc tggtaaatta
     6781 attctagctt cacataaaat atctgctacc ccttctaact caggaggttc tacattttca
     6841 tactcagttc cttttgttgg aataaggact ataaatgtaa gcttattagg aggatttttt
     6901 tgtaggtatt ctataatttc atattcaccc tttatttgtc ctccttttaa accaatacat
     6961 atatgtggtg ctacttctgt atgttcttgt attgtattat agacttcaat ataatcttct
     7021 ttactctttt tcatcttata aacttctctt attgtctcat catcaaacac taaatcaaaa
     7081 gaaactatat ctaaatactt acacaactct acaatgctat ctttatccat aagacctaaa
     7141 tgagcattca atctatatcc ttgctctttt aagtttttaa tggtattaat atgagtattt
     7201 atagggacat ctccctcata actacaaccg ccactcaata gaaagctagt tatattcctt
     7261 gattgtactt tttcctcata ttcttctatt ggcaccatat tgtttaagta gtgaccgttg
     7321 caatgggcac atttcaaact acattgattg cttgtagtac taagagctag tgtctggtta
     7381 ggataagcaa actctatttt atttccaaaa ttctttaatt taatatcaaa tgctattttc
     7441 attttttcag atagattctt attcatagtt tattccttct taagtacatt ttactcttct
     7501 agtaatttct ttgctgttgg gaactgctct atattcgtat gtggtaagaa acatgcagaa
     7561 ataaattcat ccatataact tggatataca ctaagttcaa cataagttat ttgattacct
     7621 atttcttcaa gtttattttt tgcatcttta cttataagag ctaagtaaga accaacaagt
     7681 gaactattcc ctatataagt aaatttttct ctatcgatat caggaagtaa ccctataatt
     7741 attgagtttt ctatgtctag gttgtttcct ataccacctg ctatataaac cctatctaat
     7801 atactaaaat ccatacctaa actatctaca agagtgtatg cgcctgaata tatagctcct
     7861 ttagctctga tgaaattatc tatatcaact tcattgacta ctatatcatt ttctaaatca
     7921 aattcttctt taaatgctaa tacatactct cctatctcat gctcattaaa tctaactctc
     7981 ttattatcta aatccctgta tattttacct cttctatcta ttacaccttt agtaatcatt
     8041 tgacagatta aatcaattat accagaacca catataccaa ctggtgcaca ttcatcaata
     8101 atctttaatg ttggctctaa agtatcttta tcaataatta ctttctctat tgctcctgct
     8161 gatgctctca ttccacagct tatccctcca ccttcaaaag caggtcctgc tgaacatgca
     8221 cagctcatca tataatcttt atttccaaat acaatctctc cattagttcc taaatctata
     8281 aataaaacat tttcttcact tgaccatatc cctgctgata atactcctgc tgttatatct
     8341 cctcctacat aacttgcaac agatggagct aagtacacat atgcactgtc atttacaaaa
     8401 agaccaacat tttcacccat aagttttgga gattttaaaa atggtggtat gtaaggttct
     8461 tgtcttaaga agtctgtata cacacccaag aataaacttg tcatagttgt attcccggca
     8521 gccactaatg taactacatc ttccttatct attccatttc tttcatatat tgtttttaat
     8581 agtggattta tagtttcctc aactatagct ttatgaagtg tctctaatcc atttttctta
     8641 gttgaatata taattctatt tataacatct gctccatatt ttatctgtgc atttccagaa
     8701 gatgctttat ctactacctc ttttgagtat aggtctacta aacaaacaac tactgaagtt
     8761 gtaccaatat ctattgcaac tccgtataag gaattttctt tatttccttg ttctatattt
     8821 atgattgtaa gtttcttttg tttttgaaca tatgttattg taaccttaaa atcactcttt
     8881 ctaaatacag ttggcatttt tctaagtata tccaatctaa aatctatttc attatatcct
     8941 aggttatttc taacatatct ttccaatcta tctacatcac ttatattatc atctaaattt
     9001 ggttcttcca tttctatgta tttctttttt atatttgttt taaattgaag gttatgttct
     9061 tcaattattt ttttagctct ttcaaaaatt tccctatcct cttttttatt actaccttct
     9121 atcttcatac catgcataga agatgatact ttagaaggaa cttcaatttc tatatctgat
     9181 attacctttg tacaacaagc tagtatataa ccttgctccc actcatcatc tgttatatgt
     9241 cttgtttttt ctgtatcaac ttttccattc aataatttta ctttacactt cccacaagac
     9301 acgtttccat tacaaggagc atctatgaat atatctgcat ttcttgcaac ctctagtaat
     9361 atatccccct cattacaata aacctcttta ttgtttggtg taaaacttac ttttatcatg
     9421 ttatccctcc caatttgttc tatatatgat aaaaggaaag tatagctaaa tttgcgtgca
     9481 ctcaaatttt actatacttt ccccaattat aataatatct taatctttaa ttattctaat
     9541 ccagcctcgt attctttatc acttaataac gtatcaagtt cagccacatc agctagtttt
     9601 acttttaata tccagttttc atatgggtct tcatttatac attctggctc atcttctaat
     9661 ttttcattaa cttccaatac ctcaccatta acaggagata ttaaatcaga agctacttta
     9721 gaagactcaa ctactccaaa atctactccc ttagttacag tatcttctac ttctggtgtt
     9781 tcaacaaaca atatttctcc taattgatct tgagcatagt ctgttatacc tatatataca
     9841 acatctccat caattacttt tacccactca tgatctttag agtattttaa ttctggtaat
     9901 aatttcattt cgatagaccc ccaatattat attattgatt aaattactta aatcatatta
     9961 atattatatc atattatttt aaattttcca tcaattacat tacactttcc atagctaatg
    10021 ctggatgacc tttttcttct aagaaagcta atactccttc agaatcgtca gctatagttt
    10081 catcacaaac catatcacag aagttttcta ttccagtcat ttctttaact gtagcattta
    10141 atttatcagc tacataatct tttaattctt ttggcatcca aactattctt tctggtccac
    10201 cttctgcata agcgaatttt ttagaagata tgaaatgtct tccgtgtccc ataaatcctg
    10261 gagtttgaac tcctccacct gtcatagaag caagttctcc gaaagtcata ccaactggag
    10321 taacacttgc aaattctctg ttaactacaa caaatccatt tgcttctggc attataccac
    10381 agatacattc gaagcatcca caagaagtca ttgggtcttc tagtatagag tataatgtaa
    10441 cagattcaac tgcaccttga gatatttggt ttacagtttc atttactgaa ttccatacac
    10501 ctgttctatc atctaagcac tcgccttttt ctattggttg acaaggacct gttgggtcta
    10561 gttctttagt agccttagca tctaaccagc taactgctcc acaaagacca agtctttcag
    10621 gagtaacaac acaaacgtga gctggtgcaa atgattgaca taagttacaa gaatagaaag
    10681 tgtcaacact ttcatcaact aatgaagcta atctttcatc tctagcattg tacttagcta
    10741 ttgcttcacc ttttaattca gaaacttttt cagcatctgt aattatagtt atttcacact
    10801 tatcaactac tgattcaaat tcatctaaca tcttagcata taaaacttct cctatatgct
    10861 caagtctaaa tcctttatca aatgcatctt tagagattct tacccaagcc atatctcttt
    10921 gtccaacgtg cattacacct tctatatagt ttaagaagta gtggaaacgt ctttcaagaa
    10981 ctggctcgaa atcttcttgc atatttttac cagctatttt aactattaca gcaagtggta
    11041 atcttaatac accatctgca tcaacttcat ctatatttgg tcctattatt tctatcttat
    11101 ggtcttcaac ttctgttgct tctttcttaa caacaagctc ccaagcttca gttctgtttc
    11161 caccaaactc agcaaacata tcgctctttc taattctctc accttcaaat gctgctgcaa
    11221 atgaaactgg gataggtatt tcagtaactt ttatttttat tcctctagct tctaatgaag
    11281 tagctactat cttatcgtaa tctttttgag ttaataggtt cattggaact tcaagaactg
    11341 tttggtcagt tataactggg aatcctaaag ctattgctcc agcacctgca gatacaacta
    11401 attcacttaa tggtccaaat gcattaacaa atgcaggaac tctattagct gtgtactcta
    11461 ataatccgtt taaatcacca ggagttaatc caccgaatat taatgctgct cttactgcaa
    11521 cagatacaac gtgtataaca gaagttacat catatcctag aggtataact cttagctcaa
    11581 gacccatttt tactccagct tctatagctt ggtctataac tttaccaact aagaaagtta
    11641 gtaaaccttt agattggtaa tcttttataa cttttgctgc tgattctgca tctggacact
    11701 caccaagaac aactgcaaca ccaggtatat ctcctgtaac taatggtaca ccaagtgatc
    11761 tgattatagg gtcagttata tgacctgcac atggctcact atatggagca tccatagttg
    11821 aatattttaa tgcttcaatt acttctgctg ctaaagctgt agctaaacca gcattaaaag
    11881 catgttctag taaatgagtt ctatttatta aagattttac tacttctaaa gcaccttcta
    11941 agtcccctaa agtgttcatc ttttgtcctg ttgcagcata tatacaaggt aatgaatatg
    12001 ctgtatcagg gaaagcaact ttatgctctt ttccattctt ttctatagct tcagctaaca
    12061 tagcttgagc cgcacctaaa gcttgttctg accctgtaaa gattatatta tatagattca
    12121 ttctatttcc ccctttaata tttacaccta ttttttatta actataccct aaaaacccta
    12181 gaaagcaaat ccaccttcat ttaactctaa gaaagagtct gcatataaag atgccccgtt
    12241 gattatgtca caagatttta cagttttcat taattctggg tcacatggat tcattatagc
    12301 tgaactaaat ccattagcca ttgccattgc taagaatgca ctatctaaaa caggtctaac
    12361 atgcttagga catccattag atacgttaga taatcctcct gtagttaaaa gtcccatctc
    12421 agtcatcatt tttatagctt ctaaaacttc tacttgtttt tcttgcatac cttttataac
    12481 taagcataat gggtcaaata gtatatcagt tggctccatt cctaacatta agcctttttc
    12541 taatatttct tggcagtaag ccatacgctc atcattatct cttgggatac cttcttttgc
    12601 acataaacct ataaccattg cttcgtattc agctgctata tctattaaat caaatcttga
    12661 accagcatca gcagagttta ttattggttt tgcattagtt ctatcataaa cttttagtcc
    12721 agcttcgata gcttttttat tagctgtatc taatgctata ggaacattgt tgaactcaga
    12781 ttgaagtaat ttgattcccc atgtcattat ttcttcgcca tctctttcgg caggtcctat
    12841 attaaaatct atatagtgtg ctcctgcttc taattgctct tttgctcttt ttaagattgg
    12901 agctgggtct ctttctgcta atgcttttct tattgaaggt gatatacaat gtattctctc
    12961 acctataatc ataaattttt ccatttataa tgtccccctt taaatttaat attaatagtt
    13021 agttaatatt ttattagttt gtttggcatg ctttttcttg gtatcctttt aagaacttag
    13081 gtaattccat agattcctct ggtcctataa ctacattcca tcctggtaag ttatcttcta
    13141 tatcaccttt aagtactgca acttttcctg gaatgataag gtctttacaa ttagttactt
    13201 cttctacctt actttcttta atgaaagcag agattgagtt tccaccaaat ttaccagcag
    13261 cccaagatgt aagaactgaa tatccacctg catctggtat tactaaccat actggaactt
    13321 ttgatctttc tatatcccca gcaactatga agtaagttaa tgcaaagtca acagtaacta
    13381 atactggaga attttcatct gggttgttga ttggataaat ctttggttca actctcattg
    13441 gtctttgtgg gtcagtgtat atgttttgtc ttagtgcaaa taatggtaat gccttagcat
    13501 aactaatatc atctattact attatagaac cgtattttat agtgaatatt gatgataaag
    13561 caacttccat catagggttt gaattagata atctatttgc aaatactatt gaaggatatc
    13621 caaatgttct atcttgctct tttaaagctg ttcttctaac ttgtatagca ttagtgtaag
    13681 tatcttttat gttttctcct gttacatcta atactaattc tttatatcca gcggcttgaa
    13741 ttaattcaac tgtttcatat aattcttcta agctaccagc ttttacacct aatggtaaac
    13801 ttgctccttt aactacttct atcatatctt tgtagttctc tttagttgct ccatatacca
    13861 ttggtctagc atcttttaat acttcaacag cttctttaac tacttgtgca tcatcacaag
    13921 ctaaaatata agctacttct aatccactgc cttttatttt atctattaat tttaaatacg
    13981 catctttatc tccacaatac tctaaaacag ccatttcaac tttcatttgt tcaccaattc
    14041 ttacatagtc aacttttttc atgttagcta ttttagcatc tactgcttca tcactcatac
    14101 aagtacagaa tgaaactgca tatctatttc tacttactaa tgttttttca tgtctaaata
    14161 atactgtttc tccacctagt tcatactcag atgcaccagc accaactttt aaagctttca
    14221 ttaaaggtgc agtagcctct gataattttg ctatagcgtc atcagacata tgtgggcatt
    14281 tacctacttc tacagcttct gaagcaacct tcatagagaa agccatacaa gttgggaatc
    14341 cacaatcctt acagtttttc tttggtgtta atttaaatat atctaaagct tttaatgcca
    14401 ttattttttc cccctaacct taacaattta attaagctaa tgcgttaacc aattctttta
    14461 tagtttctat tgattttgga tgacgaagta taactgcgtt tgaaccacct actaaaacac
    14521 ttgctgcagt tgaaacttcc attgctatag ttctttcttc tggacaaccc caatctggct
    14581 catcttctat tggagctata gcttctttaa catgacctac ttcaaaagct actggtgtta
    14641 tgataggcat ttgtaatgtc ttatcatttt gaccaaatgc tgcaagtcta attctatcca
    14701 tagtagatgc aacgtactca tatccataac caactgctga acatccaaca ttcataacta
    14761 tattttcacc tttaacgcct agttgagtta acaatacgtt taattgttta gctaggttta
    14821 tatcaacaga agattcagct cctactttat gtgcataagc cataccagct gatgctccta
    14881 ctcctttgta gttatcttct actgctgaca taaataagca gttatgtcca tccaatgttt
    14941 gagctaattt ttcaaataat ttaccatctt tttcatgatt tcctgaacca gctacaacta
    15001 aaggtaattt tattgcttca attactgcct tagctacatc agcacattca tcaactgact
    15061 tatctaatcc atttgggtca gaaccatcaa attttaaaca aataaaatct gcttgtgtat
    15121 tagcttcaac atatttagcc cactctactg gacaattagc tacatctttg tataattcct
    15181 tatatgaatc agtccagctt tcaggataaa cgtctgatat ttgtatccct atttttggag
    15241 aattacctac ttctccatca aaactataaa aaggtaatac attttcccca cctaatttaa
    15301 ttgctttttc ccctattcct acttcaactt ctgatatttt tccagaatat ttttgagtag
    15361 acattttaaa tgccatattt ttttccccct taagcctatt ttaattctaa tttagcaaaa
    15421 atttctttca tagccacttt agattttgaa tcttcaggta aattaactaa aggaatacct
    15481 gtagaatcat attcatatat caattcatcc ataggtacaa caccgattag ctctaggtta
    15541 tgcttttcaa tttcttcttt aacaccatca ttcataactc catttggaac tttatttaca
    15601 atcaaaagta ttcttccaac acttaacttt agttcctcag ctaaatctct tattctagca
    15661 acagcttgta tgctacgtct tgagcaatca ctaaccaata aaagtgtatc aacatgtcta
    15721 gtgacttttc tacttagatg ttccatacca gcttcgttgt ccatgactaa gtatttgtaa
    15781 tgaccagata ttttgtttac ttgttctcta agtatcccat ttacaaaaca gtaacatcct
    15841 tcaccttctg acctacccat tactaataag tcatatcctt cgccttcttc gattatagaa
    15901 tttaatctaa attgaagata ttgtgccttt gtcataccac cagggaatgc attgcctaac
    15961 ttttctcttt gatttacttc ttctcttatt tctcctattg ttgcttcaac ttcgatacct
    16021 aatacttcat ttatgttagc attggcatca gcatctacaa ctaatactgg tccctttttg
    16081 tccttaacca aataatcaat caaaagccct gtgagacttg ttttaccagt tccacctttt
    16141 cctgcaacag ctatattgta tcccatttta agacttcccc cttaaatcta gccacagagc
    16201 cttatgtact ctgtctgtct attataattt aggtacagaa tgaacacatt ctccatgtac
    16261 atcatgaagt gcttccatta gcccttcaga taaacttgga tgtggatgta ttgcatcccc
    16321 tacttgttct actgttaatc ctagatgaac agcaagtgac aactctgtca ataaatctgt
    16381 agcatgaggt cctactactg ctgcacctat tatcttatca gtttctttgt cagctataac
    16441 ttttacaaat ccttggaaat gtcctatagc ttgtgctttt ccaagacctc taaaatcaaa
    16501 ttgacctaca ttgtattcta caccttcagc ttcaagttgc ttttcagtct taccaacacc
    16561 agcaacttca ggttcagtat aaacacatct tggaattgct ctataatcta ctaccttagt
    16621 cttacctaaa gcattttcaa ctgctacgat accttcttta gaagcaacat gtgctaggaa
    16681 aggagtatct attatatcgc ctattgcgta tataccttct acattagttt caagatgttc
    16741 attaactact acttttcctc tttccatttc aattcctata tcttctactc cagaattgtc
    16801 aaggttaggt cttctaccaa cacatactaa tgcatattgt gcttctataa cctttccatt
    16861 agaaagagtt gcaacagcct taccatcaac tacttcacaa gtttgtactc caatacctgt
    16921 aataacctta attttatctt tcttaaattg tctaagtagt tgtttagcta catctttgtc
    16981 ttcatttaat agtatttggt caaccatctc aactatagtt acttctgttc ctaaggctct
    17041 aaagaactgc cctatctcac atcctataac tccaccacct actattaaca tagactcagg
    17101 tatctcttca agtccaagaa cttcatcact agttattaca acttttccat catatgggaa
    17161 cattcttggt acaactggaa cagaaccatt tgctagtatt atcttatctg cttttatagt
    17221 ttctactgtt ccatcatctt tagttacttc tatagtgttt ttatcaatta attttccaaa
    17281 accattaact aagtttactc ctcttttttc aaataagaac tctataccac ttattaattg
    17341 gtttacaact ttattttttc tttccattat ggcagtgaag tttggcttaa ctgtaccatc
    17401 tatttctata ccaaaatcct ttgcttcttt tacagtattc aatactcctg aagaggcaag
    17461 aagtgcttta gttggtatac atcctgcatt taagcaagtt cctccaactc ttcttttttc
    17521 aacaactgtt acatctgcac caagcataga agcttttata gctgctacat atcctcctgg
    17581 tccaccacct actactacta tcttcatctt taattccccc aaacctaata taatctacaa
    17641 tcttgcaata ctataaacct gcggcatcca gtatagcagg tatattctct tctgccccaa
    17701 ttgccattat atgaacacca tcacataaat cttcttcttt taattgtttg ataagttccc
    17761 ctgccatttt tattccttca cttacccagt tttcttttcc agctgctctt aatctttcga
    17821 tttgttcatc tggaacaaat attcctggta catttgcagt cataaattta gccattcctg
    17881 gtgattttaa aggtactatt cctgctaata ccttgcaatc catatccctt gttaattctc
    17941 taaactttct cattgtattt atgtcataaa gtgcttgtgt ttggaaaaat ttagcccctg
    18001 cttttatttt ctttttcatt tttaataatt gaacttctat tggagaatat tctggagtta
    18061 ctgatgctcc tagataaaaa tctggagaac cttttaactt attaccagcc atgtccgtac
    18121 ctgccattaa agtctcagca gtttgaagta tccccacaga atctaaatca aacactccct
    18181 tagcttgtgg atggtctcct acgctagtat ggtctcctgt tagtgccaac agattgttta
    18241 tcccaaatac acctgctgac aacatttctc cttgtatagc tattctattt ctatctctcc
    18301 ctgttatttg aataactggc tctaatccag catcttttaa taatttacat gtagcaagag
    18361 aagttgctct cataactgcc gattgaaagt ctgttacatt tgctgcatga actcttccaa
    18421 ctaacggctt tgcacattct attaaatgtg aaaggtcagt cccttttgga ggagccattt
    18481 cagtagtaac tgcaaatttt ccactttcta atgtttctct taataagctc atctctaatc
    18541 ccccttttaa ccttctaaaa aaaactttta tgaatttgct gctgcttctt tctttttctt
    18601 tgcacttaaa cttcttggat tattttgctt agaatagtct tttggtggtc ttatttctgc
    18661 taagttatct aattgtccta tagcttctag tctttcatat atctttatcc aagcacaatc
    18721 attctctgag tttacttcac acttaccatt tttagctcca ccacaagccc cattcataag
    18781 acctttagca cacatagtta ctggacatat cccacctgtc caaccaagtt cacagtctcc
    18841 acaagcctta caggcttctt catattctcc aactctttgt acttccccta taaacaaagt
    18901 attgttggct ggataaactg gcttatcttt taaattctta actattgtct gtgtaccatc
    18961 tccacatgct aaagataaaa ctgcatcagc ttccttagtc tcttctttta gagcctttaa
    19021 atccttttta gactttaaaa ggttacaagc agggtcaagc attacatatc ctaagatttt
    19081 tttgccttca ccttcaagag tttccttcat ttttaaaact tcttcttccc caccactttt
    19141 acaagttgct gcacattgat tacaaccaac taaaaccagc ttgtcaaaat cttttaagta
    19201 ccctagcact tcttctaatg gtttattttc agaaattatc atatctactt cccccctaaa
    19261 ccttccacat atatatatct atttattgtt ttgtaattta caagccttaa ctacatgttt
    19321 tgcaagtata gatgttgtaa ctgaaccaac ccccgctgga actggagtta tcattgatac
    19381 tttgtctaaa actgcatttg tatcaacatc tccacataaa tttccttctt catcaacatt
    19441 tataccaacg tctataacta ccgctccatc tttaacaaaa ctttcatcaa ccatcttagc
    19501 tctaccaata gctgctatta gcacgtctgc ctctgctgct acacctgata gatttttagt
    19561 ttttgaatga catattgtaa cagttgcgtg ttcacttaat aaaagcattg atactggctt
    19621 tccaactacc attgatcttc cgagaactgt taccttactt ccttttaaat caacattata
    19681 gtgttttaat atctcaacta ctgctgtagg tgtacatggt ggaaatccac ttttatcccc
    19741 ttccattacc ttagcagagt ttattggact aaaacaatct acgtcttttt ccggtgcaat
    19801 aacatatttt ataacttctt catttaagtg ttttggaaga ggtctaaaac ataatatacc
    19861 attaacattt ttgtcatcat taactctctt taatacatca atatattcct cttgtgttat
    19921 atcctcagct aactctaaca cttctgttgt tatacctatg ttttgacatc tctttagtgc
    19981 tcctctttca taagataaat catcacttct tgccccaact ctaactattg ttagtttagg
    20041 atttatacct tctttaacta gtaaatcgac ttcttttatt aattcttcac taattttatc
    20101 agctacaggt tttcctttta taatttgtcc tttagttgac attccttcca tacattcaca
    20161 actcccctac aagcaaactt aaattaattt attctatata ccacatatta ataacatagt
    20221 atctactttc gtcatttaaa aattattttc caagagcttt ttcaactttg gcataaactt
    20281 catcacaaat ttttacacca tcttcaacta acttatctac ttctgttttt accttattaa
    20341 catattcttt atcttgtata gaatttatat ttataactac atttaattgt ccaccaagta
    20401 tagcagctct taaacactga actcctacac caacatcact tatagcaagt cttgaacctt
    20461 tatcaactaa atcttcatgt aacttaatag cttcatagca aactcttact atgtttaatg
    20521 gtacttcaca agcaactttt aatgcctttt ccattgtttc tgcttttatt cttttttctt
    20581 cttctgtttc tttaggaagc ccgtaagctt ttgataatgg taagaaacat tctgcatcat
    20641 catctatcat ttttaataaa tctttttcta actttcctgc cttacttaat atctctttta
    20701 cactttcttc atactcagca tacttcttct tccctattgt aaggttacat accatactac
    20761 ctaaagccat acctattgca cctactagtg cagcagctcc cccaccacct ggtactgctt
    20821 ctttggaaga tagtacttct acaaaatcaa cacaagtttt atctgctatt ttcatgataa
    20881 tcctccttga aaggatgtag gaaaatatct caaattgttc gagatatttt acgaactatt
    20941 ttaagatatc tcctactctt tatttataaa ttaatttcct tagaataatc cagctattac
    21001 tccattttca tcaacatcta ttttttctgc tgctggaact tttggtaatc ctggcatctt
    21061 cattatttct ccagtaagtg caactataaa tccagctcct gctgaaattg ttgcttgtct
    21121 tacagttatt ctaaatcctg ttggtctacc taatttagtt tggtcatcag ttaaagaata
    21181 ttgagtctta gccatacata ctggaacttt agtaaatcca agtttttcta agttagctat
    21241 ttccttatca gcttcaggag tataatctac accatctgct ccataaatct tagtagctat
    21301 agcatttatc ttgtctttta tagataaatc atcttcatag cagaatctaa agttattttc
    21361 ttcttcatcc aataatctta aaacttcttt agctactgca attccacctt ctccaccttt
    21421 tgcccatact tcagaaagag caacattaac acctaattcc ttacacttgt cttcaacaag
    21481 tttaagttca gcttcagtat caagtgggaa tctgttgatt gcaacaactg ctggtaatcc
    21541 atatacttga gttatgtttt caacatgttt taataagttt ggaagtcctt tttcaagagc
    21601 ttctaggttt tcgttattta agtctgcttt agcaactcca ccattgtatt ttaatgctct
    21661 tacagtagca actattataa cagcatctgg ttttaagttt gccattctac attttatatc
    21721 taagaatttt tctgctccaa ggtcagcacc gaaaccagcc tcagttatta cataatctgc
    21781 aaagtgcata gccattcttg tagctataac agagttacat ccatgagcta tatttgcgaa
    21841 tggtccaccg tgtacaaatg atggtgttcc ttcaagagtt tgaactaggt ttggttttaa
    21901 agcatctttt aataatgcag ccatagcacc attagctttt aattgtctag ctgttacagg
    21961 ttcaccttcg tagctgtatc caactattat gtttcctaat ctttctttta aatcagatat
    22021 atcacttgcc aaacagaacg ctgccattat ttcagaagca acagttatat cgaatccatc
    22081 ttgtctaact gctccatcac cttttttacc cataccatca acgatatttc taagttgtct
    22141 atcgttcatg tctacacatc ttctccaagt tattttctta gggtctattc taagtgcatt
    22201 tccttggtga atatggttat caagcatagc agctaaaaga ttgttagcag ctcctatagc
    22261 gtgaaaatct cctgtgaagt gtaagtttat atcttccata ggaacaactt gtgcatatcc
    22321 cccaccagct gctccacctt taacaccaaa tactggtcct agagatggtt ctcttaaagc
    22381 aactaataca tttttgtcta gtttagcaaa tgcatcagca acacctatag tagtagtagt
    22441 ttttccttca cctgctggag ttgggtttat agctgtagtt agtattaact tagctttttt
    22501 accagtctct ctttttagta gattgtagtc aacttttgct ttgtatttac cataaagttc
    22561 tacatcatct tcacctagtc ctaatttttt tgcaacctct ctaatatctt gaggcttagc
    22621 ttcttgagct atttcaatgt cagatttaaa tcccataact gaatctcctc ccacaaccta
    22681 aatagattta aaatataatt tttgtaaaaa ttgtattaat atgtaaaaat tatattttat
    22741 aagataatta tacatgtaaa attacttaaa aactagctac taagctatta aaatattcaa
    22801 acttaatagc tagttattta tctaattact tacttattac ctatctattg cctatgtcta
    22861 acctttaacc aacttaaaat cccaaatcaa aatttctatc tattttattt atccttaagt
    22921 gacattaatt tatcttttat tgctttaatc tgttctttcg ttgtttcact agaatcatat
    22981 ggagattgat tggctctatc agaatcaata acatcttggt tataataaat aaatcctaaa
    23041 gattctccat cttctaagtt ttggattata aattcttcat cttccttatt tctaatttta
    23101 tttcctacta caaatacttt atttacacct atatcatgtc caagtttctt aacttttcta
    23161 taagtctgta gacttctctc tcctggttct acaactacta taaaagcatc tacaccttgg
    23221 gctgttcctc ttcctaagtg ttcaattcct gcttccatat ccataacgac tacatcttta
    23281 ttttgtagta ttaaatgtga gcagagtctc ttcaaaagaa catgctctgg acatacacat
    23341 ccagtaccac cagaatctac ggttcccaat gtaagtaatc ttactccatt gtattcttta
    23401 cagaaatttt cagggatatc gtctacttta ggattcatct taaacatttt tccaaatgaa
    23461 cctaaagaag cagctgttct atctgaaact aattttttca tttctgatat aggtactatt
    23521 gattcatata cttcttttgg aaaacctagt gctaaagcta aattagcatc agggtcggca
    23581 tcaacagcaa caactctgta tccgtcttca gcaaacatcc tagagagcat tgaagaaaaa
    23641 gtcgttttac ctactccacc tttacctgtt attgctatct tcataatccc taccaccttt
    23701 tattactatt tgctttttag tagttaattt tacagttaaa tattttttat actctatatt
    23761 tttatacact aaaaataaac tacagctagt ccttacagga accaattaaa tttaccctac
    23821 tagcttttca aagcagcatg tatagtttta ttattcttta atattgttta tattttattt
    23881 attcagtata ttcattatat tttgatgttc tttactttaa tatttgactt tattcaactt
    23941 tactcaacca gaaacttctt ataaaaacgt ttattctata acttcactat tttttaagct
    24001 tcagcctttt ctgccatttt ttcttcaact aatgcttcaa agtgaacacg ttttttctct
    24061 atatcttcta ttattgtagc tgctaactct tttggatttg tatttacagt aaatgtagct
    24121 ccaactttat cttttaattc actagttaat atatccactg ctcttgaaga accagctatt
    24181 ggaggcatta ttcctaaata agtgtctata ccagaagcta caacatagca tcctatagca
    24241 actgcttttt ctgacatcca ctctggagct atacctacaa ctggaaggtc acacatatcc
    24301 atatctaagt aattagctgc tgctccaacc aaatctagta tacgacttat atcaacacaa
    24361 gaacccatat gtagtactgg tgggattcct actaatttac agacagttgc aagaccttta
    24421 cctgcatatt tttcagccgc atcagattcc attaaaccaa acttagctgc tgctgaagct
    24481 ccacaacctg tagtaactac tattatgtcg tttttgatta attctttcat tattgttacg
    24541 tgagcctcat ttgaaactcc tttagcattg ttacatccaa ctacaccagc tgctcctctt
    24601 aatactccag cttttagaca gtctgttaat ggcttaactg ttcctgctgg gtctatatga
    24661 gagtttacaa ctctgtctaa ttgatttact actgcttcta cactataccc aactgttgcg
    24721 cctgatttta attcaggtat aagtactttt gatttatctc tatttttaaa gtttaaaata
    24781 gcttctttaa ctattgcttt agcatcatca agtgcttgtt cttctctaaa ttcaatataa
    24841 gttgaacctg ttatcttagc ttttggagaa gttgttacaa atttagtatg gtaacaatct
    24901 gcaactctag ctaatgcagg gaatatacat tgaacgtcaa ctattacagc ttcaactgct
    24961 ccagttatta ttgcaagttc ttgttgatgg aagtctcctg ctatttttac accatgtctc
    25021 attgtaatct cattacctgt acaacacata cctgctaagt ttattccatc agcaccaact
    25081 tctttagcta aagctactaa gtctggctct tctgatgcta aaactatcat ttctgataat
    25141 gctggctcat gtccatgtaa tattatgtta actttatttt cttctaatac tgctaaattc
    25201 gcctctgttc ttcttggcac tggagttcca aataagatat cgcttagacg agtacctatc
    25261 atagaaccac cccaaccatc agccatagaa gttctaagac tcatgtgtat taaactatct
    25321 atatcaccag tacatcctat atgagtagag tgcattattg ttgcaatttc tctatctata
    25381 gctcttggct ctatagcgta ttctttccat attttttgtc ttggttctgg tgcatttttt
    25441 ataaatctta atgtcccaaa aggttttcca aattccatta atgcaatttc tgccacttca
    25501 tgtgctacat catagatatc tctaccttct gtctctacat cccattcttt agctaaagta
    25561 attaacttag cttcgtctct tattttatag tttccatttg gatcagctaa tgctaatgta
    25621 tgtgctatat ctctagcatg gtctgaatgg gcagctgtcc caccagcaac cattcttgca
    25681 aagtttctac ctactatagt atgctcatct gctccacata acccccttgg agtcttaggg
    25741 cttattctac atggtcccat tccacatatt ctacagcaaa caccttgaag accaaaacca
    25801 cattgtgcct taaagccttc ttttctatca tacattgttt ctacgccttc ttctctagct
    25861 ttagctatca tcttctggct gtttaaatca attgttaaca ttttttcatc catattccta
    25921 tccccttttt ttgattttta aaatccccca ggtgactgac ttcatgtcat aaaataataa
    25981 aataaatgct ttctaagttg attatatact aattttcagt gctttgcttt agatttaaat
    26041 atttttttaa caaaattaga taatacataa aaattttatt ttctacactt aatttaagtt
    26101 gattttatcg cttgtttttg gctatttgtt aatatctaaa cctacttttt tgatacttca
    26161 gtttaattaa attatgtttt gattttttta aatcaaattt gaaatttttc tagtcatttt
    26221 tatattattg cagattgttt gtgtatttat tatctttcac tactgtttgg acttattaca
    26281 gatttttact ccctaaactt aattagtaaa aatttcttag aatagcattt tttggactaa
    26341 tttttttgaa tttttttatt tttcctactt taatattaat tatagcttca aattgaacat
    26401 ttgtatatat tcatttgaag ctataattat tttttatata aaactttttt aatacagcat
    26461 taatttagac attttgacta ttttttctac tttaattcat ttatttcaag cgatttatcc
    26521 tatttcatat ttttagctac aatagcccca tatgcaatag aatataattt agattcatgt
    26581 gaatcagctc ttgacactaa aactatagga gcttttgcac ccataattat acctgctgat
    26641 ttagagtctg ccatatatgt aaaggctttc cctattccat taccaacctc tattgttgga
    26701 accaatatga tatctacatc tccagatact tcacttttaa acccttttat ctcactagct
    26761 tcttttgaaa cagctaaatc aaaagccaga ggaccttcta caattacatt ttcaccaaat
    26821 tctccttctt tacaagcttt tgctaacata tctgcatcta cagttgcttg catcttagga
    26881 tttactttct ctttagctgc caaacatgca acttttacag tttccattcc taaagctttt
    26941 gcagctttta tagaattttt taatatcttt gccttttgtt cataatcagg agctatattc
    27001 atacctccat ctgtagttat aagtaattta tggtattttt ctaactcata taccataaca
    27061 tgacttaata aactatcagt tctaagacca tagtctttat ttaacacttc ttttaatatg
    27121 acagatgtat ctaataatcc tttcattaca aagtcggctt ctttacttga tactaattta
    27181 actgctattt ctgcacactc tttgatatca tccttatcca ctattttgat accacttaaa
    27241 tcaaatccta tttcttttga tatttctctt attttgcctt catttccaac caatatagga
    27301 gtaattatat ttctttctac agcatccttt attgccatta aaacttcttt atcatgagct
    27361 gctgctacag agagtacaat tttctctcct cccttaagtt gttctaaaat atcatctaat
    27421 ttttttatca aaagtaaccc ctcccttata tatatttaac taaataatac catatttgct
    27481 ataccttttc tcaatttatt ttttatgtta taaagaattt atataactaa aagacagttt
    27541 aatattttat tctgggattt catcaataac tcttaaaagc tttgcaggaa caccacctac
    27601 aatagtattt tctgcaacat tttttgttac aactgctcca gcagcgataa ttgcattatc
    27661 tccaatagta actcctggaa ctacagttac attagcacca atccatacat tttttcctat
    27721 tgtgattgga gaaggataag ttgtaccacg tttctctggt gcaataccat ggttaagtgt
    27781 agccaatacc acattatgcc caatttgcgt attatctcca atctcaatcc ccccctggtc
    27841 ttgaaaatgg caactgctat ttataaaaac attttttcct attgtgatgt tttttccaca
    27901 atctgtataa aatggtggaa acataaaaaa tgattcatct accttttttc caattaactc
    27961 agaaaataaa ctacggactt cttctggttc atgataagaa gaatttaact tacttgtgat
    28021 tttcattgcc tcattactca acttaaccat aaattcatgt atttctgatt tactagaaac
    28081 aggttttctt tgattgatat gtgttaaaaa ttcattgata ttcattttat acatcctttc
    28141 aatatgtgct ttaatttatt tgtacattct aaataatatt ttaataaaaa ttaatttaat
    28201 ttatttttat taaaatatca ttgcttcttt tagtgtaata tacaattata tctatatcaa
    28261 atatctatat taaatactta actatactta aaaagcattt aaattgatat aattatataa
    28321 taaataagtt aatattgagg agggataatt atggaaataa gagtattaag atatttttta
    28381 gcaattgcaa gagaagaaag tatatctggt gcggcaacct ttttacatat aacacaacca
    28441 acactttcta gacaaattat ggaacttgaa gaagagttgg gagttaaatt attggttcga
    28501 ggaaatagaa aaatcacctt aacaaatgaa ggtaggcttt tacataaaag agcagaagaa
    28561 attatatcat tagttgataa ggttgaatta gaatttgaca atcccaatga gattattagt
    28621 ggtgatatat atataggaag tggtgaaact gaagctatgc gacttatagc gagaactgcc
    28681 catcattttc atcaaaaata ccccaatgta agatatcacc tttttagtgg gaatgctgat
    28741 gatgtgactg aaaaattaga caagggactg cttgattttg gtattttaat tgaacccgca
    28801 aatatacaga agtatgatta tgcacaaatt cctgctactg atgtatgggg tttactaatg
    28861 cgtaaagata gtgcccttgc atcacaaagc acaataaatc caaaagattt atgcaatata
    28921 cctcttatta tttcaagaca gacacttgtt gataaagcaa tttctaaatg gcttcaaggc
    28981 agtaatgaaa aactaaacat tattgcaaca tacaatttag tttataatgc ttctcttttg
    29041 gtagaagaag gtctgggcta cgctctgtgt ttagatagac tcgtcaatac tacagaaaac
    29101 agtaatcttt gttttagacc tctatctcct cctttagaag ctaaattaaa tattatatgg
    29161 aaaaaacatc aaatattttc aaaggcagca gaaaaatttt tacttcaaat acaaaaagat
    29221 ttttcttcta tcatgttgga tacatctaag ttggatacac ccaaagaaaa ataaatcata
    29281 ataaaaagtg agagtgtctc aaaatgaact ttgcactgta taaggcactc ttttttatac
    29341 aaagtaaaat atatgttcat catttcagca ctaaaaaaga ggcttatctc tattttgaga
    29401 tagccccact taaccaataa aattaaatac aacttaacaa tatccttact tatttattcc
    29461 aagttctctt agacaagcaa tagtaatttc atcttgtgga tttaattcat aagctctttc
    29521 tatatagtaa gttgcatcat caatatcacc attatttaaa taagccattc ctaaattgca
    29581 aagtatttct gggtcttcct ttatcttagc cgcttgttca aaatactcta ttgctttatc
    29641 taaattattc ttataagcct cacaaagccc caattccact atagtatcca cttgattagg
    29701 ctttattatc aatatcttct caagatacat cttagcctgc tctatttcgt ccataccctt
    29761 atatccaagt gctatcataa acagcaagtt ccaccaatcc atatgttctt cttctaatgg
    29821 aagtaacttc tctaatcctt ccttaaactt accttggaat acaagtgtat atccttcttc
    29881 atattgaact ttaaagtcca tcttgcccag attctcttgt acctcagcta ctaaatcagc
    29941 atctaaccct agccttaacg cttcttccca agtcagctta gtctttaaat attgaccttg
    30001 attataataa tggtagccta agtgataata acctaatgca aaattctcat caacatcaat
    30061 taccttttca agcttagcca tggcttcaag taagaatgca ttcattgcct tatcatccat
    30121 atctttttga tactgtttag ctatctcttg gcaaacaatc gcatagttat acattgcatc
    30181 taaatcatct ggatacattg ttataaatgc ttttatatat attaaagaat ctgtatgttc
    30241 accaatctca aagtattttc tcgacatata tcccatatac gatttcaaat ccaaatcaat
    30301 atcttttgat aaagcattta aaaacttctc atactctgca ttgtttttaa acttactatc
    30361 tattccaatt atatatatca ttgcatctgc tatagacatt gaatttaact tatcttgagc
    30421 agtcttttct tttatccctt ttactaatac ctcatttttt ataggtacat ctaatccacc
    30481 ttttggcact tcatagcttt ttaatttaaa ctctccacca tgttttatag ttataaaagc
    30541 taattcttct gcttttttta gcaaatattt ttctatctta aaatccattt tatcctccta
    30601 aatacttaaa tctctacttt atgagtttta gatttctcaa atattttttt atcatcatac
    30661 tcaaataaga ctacattttc tacttctctt atttctgtat ttatatcatt ttttaaatcc
    30721 acaacattaa atctaaatgg ctcaaaatga acatatttta ttatatgttt agctggttta
    30781 tcaacaaaac taggtaaata tgttgataag ttatcattat cttgtaaaaa tacatggcat
    30841 ctattcttaa aatcatccac atctagctta ttaaaaaact gtggtatatt tgatgtttta
    30901 cccagtgata tatagtcata ttttaatata tcgttgaata catcattatc tatgttgatt
    30961 ttttcattat agaaatccat caatatttta tataactgat tctttccttg tgccaaatca
    31021 aagtagccat tttcatcaaa atacttggca aaaacctcaa agaatttaaa agggctttgt
    31081 ttataaaatc tgcctataat atatctcata gataacacaa agtttttaga attgtagtat
    31141 ctctccagta tatcttctat atcctttagc ttcaaagttt cttcatagct tatataatta
    31201 ttgtataaaa actcatatgg agcataatcc ttatatttaa aaccatgctc atctgcaact
    31261 tttctcatac ctgtcccttt aatcatcttt aaaaagccta attgcagatg ctctatacct
    31321 agattaaata catcattaaa agaattttca aagctcttat aatcttcata aggcagtcct
    31381 gcaattaagt ctaagtgctg atgtatattt ctataagatg ctacagtttg tacaacatga
    31441 gacaactttt taaaatcatc ccttctgcct actgcatcaa gtgttttttc attcgttgac
    31501 tgaaccccta tttcaaattg aaaaagacct tctttacaat cagccaaaaa ctcaagcatc
    31561 ttatcatcta tcaaatacgc tgtaacttca aaatgataag ttgtatatcc attatcattt
    31621 ttcataagga aatccatgat ttccatagcc acttttctat ttgcattgaa tgtcctatct
    31681 ataaacttta tctgtgatac tcttgcatct attaaagctt ttaaatcact ctttatcctg
    31741 tctaaactaa aataccttag acctggaata gtagatgata aacagtactg gcagttaaaa
    31801 gggcaacctc ttgatgattc ataatacact attctatttt catattcttt tggattcaag
    31861 ttttcataag gactaggaat ctcatccaaa tcttgaagta attccatagg cttattcact
    31921 attatctcat tgccttgtct atatacaagt ccatttacat catttatttc catctttcct
    31981 tgcaagtgaa gtactaagtc tctaaaaatt aattctccct ctccataaag tatataatcc
    32041 acaaaatcat actttttcat tgcctcataa ctatcataac tcacttccgg tccgcccaaa
    32101 gctattttag tattaggtct aatttttttt agattatcac aaagtttaac tatatctccc
    32161 acattccaga tatatgttga gaataatatt atatcatatt catttttata tatatccttt
    32221 aaaatatagt ccaaatcgtt gtttatcgtg tattctttca tattaacttc tatcaaatct
    32281 cttacaaatt cttttagata tcttatagcc aaatttgtat gaataaactt ggaatttaat
    32341 gttgttaata aaattttcaa atatttctca cctcttttta agattatact gtctttttgt
    32401 accccttata ggttaaaata gtatatgtaa agtctaaata atatctatat aattaattta
    32461 ttaatttcaa gtaatgtgag gaaaggaagt tttttatgga attaattgaa aaagtatcta
    32521 tcaactcttt atcaaaaaga gatttactac ttattataaa gtctcttgaa tacactaatg
    32581 aaaatactca aattagtgat ttcattgacc ttaggaataa tatagtaaag gaattatgtt
    32641 ttttaactga cactaaggaa aaagattttt tagattatct agaaaaaaat agcacactct
    32701 aataacctaa acctttttaa actttaatat ataaatacct gatttagaat ttatttttat
    32761 gcttaatata ttatcattaa aggttttcga cataactgtt atttgattaa atatagggtc
    32821 tactatagta ttaccttctt caagtcttat aagacttctt gggtctatgc ttttattata
    32881 tgccttaact ccaattttat attttctcaa tttaacaaca tattcggaca tagaaaaaat
    32941 aaaatctata ttatcttcat ttaatttact atcttcaccc aaaatggata atatagattt
    33001 ttttatgcta ttaattcctt cattttctac agttctatct tccatatata catcatatag
    33061 aacatttaaa acatttaata aaatactttc ttcatcataa tcttcagatt tcaaatcaat
    33121 gtacttatca attaattgta ttgctttaat ccttgccatc tgaaatttta caacatctga
    33181 tttgtctaat tctatagaaa atcctattgt cttgtcttta atactctgta gtaattcgac
    33241 atactctatt ttactattat ttataagatt gtgcataatg gaattataca ctacagaacc
    33301 taataaataa tcaaataaaa gttcttcttt tttaaaataa ataacatact tttttattag
    33361 tttaataacc tcatcttcac ttttttgaat attagtattt gataaaatta gtggtaataa
    33421 aatatttaaa aaattgatat ttcctatttt ttctccataa aatctatagt aaataagttc
    33481 atctctcagt ctattttcgt ctatatacac acatctttgc gttttatcat ctattaagga
    33541 ttttgtattt attatagtta aatctttaag agccctactt gcactactaa aagaagatgt
    33601 gtagactttt tttagtaatt cgtcattcat aaatatatcc tttctgaaaa attgaatgta
    33661 aataaattgt tattaaaaaa aaagagacag cccgtttaag aagctgtcat atataggggg
    33721 atagtagtgt acaaaaatca ttgtaatcta ctatctatat attattatac gatactactt
    33781 ttttatatgt aaagcatcag ttttcgacat ccctatattt tacagttata caaattgcgt
    33841 actaagttca attttattct ttttatttca acattttatc atgctacatt ctttcaggag
    33901 cgtgcattcc caacaatttc agagaatttt ctaaagtttg ttttgttgct aaaactaatg
    33961 caagtcttgc ttttcttatt tccaaatttt ctactaaaat tggattgtca tgataaaatt
    34021 tattaaacgc ttgagctaaa tctagcataa atctagtcac tatatgtggc tcatttttct
    34081 ttagagcaag taaaatattc ttattgaatg attctataac tctaagaact tctgcactat
    34141 cttcatcagc taatagacta taatctatat cagaagtcac ttctacttct gcttttctta
    34201 aaactgcaca gcatctagca tgtgtatact gaacatatgg tccagtctca ccatcaaaac
    34261 taagcgttct ttcccaagag aaggtatagt ctttaattct actattagat aactcttgga
    34321 atactactgc cccaacacct acttgcttag atatttcatc cacattttta gcatttgggt
    34381 ttttagctag tataatttcc ttagttttat ctatagcttg atttaaagca tcttctaaaa
    34441 atactactct tccttttcta gtcgacatag taccttcttc aagtgcaacc ataccaaatc
    34501 caacatgaat taaatctttt gcccaatcat atcccataag ctcaattacc ttaaaccatt
    34561 gttggaaatg taagttttgt tgagaaccaa ctacatatat acacttgtca aaatcataag
    34621 tttcttttct atatattgca gcagctaaat ctcttgtcat atataacgtt gaaccatcat
    34681 tcttagtaat aagtgctggt ggcattttat actcttctaa atcaacaatt cttgctcctt
    34741 tagactcttt taaaagattt ttctcttcta atagttcgat aactctgttc attttatcag
    34801 aataaaaact ctctcctgct aaagaatcaa attctatatc taaaagttta taaactctgt
    34861 taaactcttt taaactctca tttctaaacc attgccataa ttcttgtgct tcttcgtcac
    34921 cattttctaa tttattaaac catgctcttg cttcatcttc catttctggg tgttgttcag
    34981 cttcatcatg gaatcttacg tataatttta gcaattctgg aattggatta gactctacta
    35041 cttctttttc tccccacttt ttaaaggcca ctattaactt accaaactga gttccatagt
    35101 cacctaaatg atttattctt atagtcttgt atccttgcga atcatatatc ttatataaag
    35161 cattacctat aactgtagtt cttatgtgcc ctatatggaa aggttttgct atatttggag
    35221 aagaatattc aactattaca gttttatctt ttccaaaatc actatgtccg taattttctt
    35281 tttcgtctaa aactttttta attacagttt ctgctaattg agatttattt acaaagaaat
    35341 ttacatatcc gcctaattgt attacttttg ttatctctcc acttggttct atactttccg
    35401 ccaattcact tgctatcatg tttggagctt ttctaaacac tttggctaat ttaaagcatg
    35461 gaaaagcata gtcccccata tccttatttg gtggaacttc tataagtgcc tctatctctt
    35521 ctttcgataa atcttctatt ttttctttaa ggcaatttga tattgccacc ttaaaatctt
    35581 gcattctgtt gctcctctct acattgttcc tggtttatat tgtgcttatc tctttatgtt
    35641 aaatcaaatt tcgtgttttt tcaagtattt cattacagtg taaaacactt tagtaattat
    35701 gttttctgta tatattaaaa atactataat tgcagttttt aatcacacta ttattgattt
    35761 tttataagac ttttttctat tttattgttt cttgtactat ccagttgact ttatatactt
    35821 tttttaatct tttatctatt ttcatacgtc aatgctaatt ttatatactt ttcttttaat
    35881 cttttattaa ttttcataca tcaatgttaa ctttatatac gtttttttaa tcttttatct
    35941 attttcatac atcaatgtca gctttatata ctttttttac tcttttatct attttctata
    36001 aatctttttc actcttaact tttattcctt cttcttctaa tagccttgct gttatacctt
    36061 tccctggtat ctttttacct gaaaaactac catcatatat tagattacat ccacaagagg
    36121 ggctaccctc ttttagtatt gcttcgctac atacatataa atttgctatt tttagagttt
    36181 cattagcccc tcttacaaag ttttctgtta catccttatt atctttagta attacttttc
    36241 catcaactat ctcagcaggt ggtcttggtg tagatagacc acctaactgc tctgggcata
    36301 caagtgtaaa ttctttgcct tttaaatatt ccttgacttt ttcattatca ttattatcgc
    36361 cactatattt acaatttatt cctattaaac atgcagatac caatatcata aaaatgtgct
    36421 cctatacaaa ttatatatat tctcatacaa attactaatg tattcttata caaattattt
    36481 taatttaaca attgttactc ctgctccacc ttctccatat tgaccacctc tttgtgattt
    36541 tacatgtcta tttcttctta aaatgtcttg tagccctgct tttaatactc ctgtacctat
    36601 tccatgtatt actgttacag actctaaacc tgccacatat gcatcatcaa gatacttttc
    36661 tacttccatt atagcttctt ctaggtttaa ccctctaagg tcaacttcat tttttacact
    36721 accagatttt gaccttataa tgtttctcgt tgatttagtt acatttgttg aaacatcttt
    36781 gcgtgttttt tgtaaagact taaaaggtag agtcatcttc attataccaa tttgcactac
    36841 tgcttctttt ctctttttat ctactgaaac tacactacca ttttgattta aagttattac
    36901 cttaacttct tcacctggct ttaagtcttt tatctcctta tttgatacct ttggaactat
    36961 catacttttt actgttggct gaagacttcc catagagctg gtcaattctt ttctaagttc
    37021 ttctatctta cgattctttt cttttgaagc tctttcttgt tcaagacttc taagttcttt
    37081 tattataata tctacttctt ctttagcttg tcttataatt gaaaatgctt ctgatttagc
    37141 tttttcaatc atcttatctc tttgactgac caatttttca agcttttcgt catactctac
    37201 tttcagtttt tcaatctctt cttttaatct ttcagcttct tctctatctt ctactgcttt
    37261 gattctattc ttttcaacat tctgtaacac atcttctaaa gctatgtttt ctgtatttat
    37321 atattcttta gcacgtgaaa tcacataatc acttagccca agttttctag aaatctcaaa
    37381 cgcatttgat tttccgggaa cacctataag taacttatat gttgggctta aagtttctat
    37441 atcaaattca actgctgcat tttctacacc tggtttagta agagcataat ttttaagctc
    37501 actatagtga gtggtagcta tacatttagc tcctacagaa tttatatctt ctaatactgc
    37561 tattgcaagg gcagctcctt caacagggtc tgttcccgct cctaactcgt caaatataac
    37621 taaagagtct gctgttacgt tttgtaatat agatactata ttcgtcatat gagatgaaaa
    37681 tgttgataga ctctgttcaa tactctgctc atctcctata tctgcaaata cattatcata
    37741 tacacacata ctacttccat aatcagcagg tatatgaagt ccactttgtg tcataagtgc
    37801 aaatagacct acagttttta ttgtaacagt cttaccacct gtgtttggac ctgttatcac
    37861 caatgtatgg aagtctcttc ctaaataaat tgtatttgct actaccttct ttttatccag
    37921 cagtggatgt cttccatttt ttatgtttaa atatttatcc tcatttaaag ttggttctat
    37981 tcctctcatc tgtatagaaa gttttccctt tgaaaatgca aagtccaatc ttccaagtat
    38041 ctcttgatta gaaattaagt cttcactaac ttctccaacc atagcagaaa gctctgataa
    38101 aattctttct atttcttctt gctcacctag ttttaactgt ctcaattcat tgttcatctc
    38161 tactatagtc attggctcta taaaaagtgt cgcaccagaa gatgactggt catgcactat
    38221 accagctact tgcgacctat attcagattt tacaggtact acaaatctat cacctcttag
    38281 agaaattatt gcatcttgta agtacttttg ataagtagtt gaacttatta ttgaatttaa
    38341 ttttgaccta atggattgat ttttttgggc tattcttctt ctgatatctc taagtgtact
    38401 tgaagcattg tcagatattt ctacttcact aattatagca ttgtatatct ggtcttctat
    38461 gtccttgtat acatatagag aatttgatag agattgtatt attggataat taaaatcttc
    38521 ttcatcacta ctagataagc tatttcttaa tcttctagcc actcttaagg tatctgctat
    38581 cataatcaga cttcctgggt caagagaagc acctatataa gctctcttta ccttatcttc
    38641 tatatcatga ataccttcca accctactga acctctcttt ataataattg attgagcttc
    38701 actagtttct tctagcatag atttcacttc tacaaaatca gtatttggta ctaaattttc
    38761 tatatatttt agacctaaag aagatgaggc tttcttcttt aacaaatcta ttattttatt
    38821 gtattctaga actcttaacg atttctcatt cattttctat attcaccatc ctcgatattt
    38881 taactttttt atttaatttt aaaaatgtat gttttcaagc atttccaata aaaactgcaa
    38941 gttttatttc tttttcattt ctaaaattat tatatttttt ctcttttaga tatattttac
    39001 acatattttg tattatacta tgtatgtagc tatctatata ttatacataa acatgcttta
    39061 tttgtaatat aatctgttaa aaaatcttct ttaatatttt taaaggagtt tattttagct
    39121 tataaaaaaa aatagctact tatatagata aattaaggag gaacatgagt catgggaaac
    39181 gtattagaag gattaaaacc agaaagtgtt tttaaaaact ttgagaaaat atctcaaatt
    39241 cctagaggtt ctggaaatga aaaaggcata agtgattttt tacttagctt tggtaaaaat
    39301 ttaggtcttg aaactattca ggatgaaagc ttaaacataa taataagaaa gcctgctaca
    39361 aaaggatatg aaaattgtcc aggtgtagtt cttcaaggac atatggatat ggtttgcgaa
    39421 aaagaaaaga atgttgaaca tgattttctt aaagacccta taaaattaag aattgatggt
    39481 gacatgatat atgctactgg aactactcta ggagctgaca atggtatagc tgttgctatg
    39541 ggtatggcta tattagaaga taatacttta gagcatcctg cactagaagt tttagttact
    39601 gttaatgaag aagatggtat gaatggtgca gatgcactag accctagctt aattaaaggt
    39661 caatatatcc taaatatgga ctccgaggag gaaggatact tattagttag ctgtgctggt
    39721 ggtaaaactt gtgttgttag tttacctgtt gaatacaaaa aagttgaagg tgacaaacaa
    39781 ggattattag ttgaggttac tggactatta ggtggacact ctggtatgga aattgtttta
    39841 caaagagcaa atgctaacaa agcaatagct agagtattaa gtgtattgaa tgttgattat
    39901 gaattagctt ctgttgatgg tggtactaag cacaatgcta tacctcgtga agctaaatgt
    39961 gtaatagctg ttaataaagc tgatgttgaa tctgctaaaa aacaaataaa tgacatttta
    40021 actgcattta aacatgagtt tactacttct gaccctggca tgacttactc agtagctgaa
    40081 acttctgtag acaaagttct tactaaagat tgcaaagaaa aagttgttca aatgtcttgc
    40141 ttaactcctc atggagttca atcagtaagt cttgatatag aaggattagt tgaaagttct
    40201 actaacttcg ctataattga aactaaagaa tctactattg aatttttaac ttctgttaga
    40261 agttctgtta tgtctattag agatgaaatc gctgatagaa taagactttt ggctcaagct
    40321 ttaggtgcta attacgacct tatagctcaa tacccagctt gggaatttaa aaaaggctca
    40381 aaattagaaa aaatatgcag tgaaacttat gagaaattaa ctggtaaagt tcctactgtt
    40441 atggctctac atgctggtct tgagtgtgga ttattacttg ataaacttcc tcatgctgaa
    40501 gctatctcta taggaccaga tatgtttgat gttcatactc caaatgaaca tgttagtatc
    40561 ccttctgtag ctaatgtttg ggattatgtt attgaaatat taaaatctat gaaccaatat
    40621 taaatttaag ttttgattct aagtagattt taattttaag taatctatat aaaattaact
    40681 ctgtaaatta atactactgt tagtataata tttactttca atattaactt atagaaataa
    40741 agcctaatga tagataataa catgtatcat taggctttat tgtaatttaa atattattaa
    40801 gctttattct gttttaaaat taattcttat actattttaa atctatttct tccttgtctc
    40861 ttagaatcat aaagagcatt atctgctatt tgatacagtt catcatactc ttgaccaggc
    40921 tttgctataa ctacccccat actaatagat aaactttctc catttggcaa cttaatgaga
    40981 tgaatatgat tgtatacatc attacattta ttaataagtt cttccttatt tattatatca
    41041 ttgatataaa cactaaattc atctccaccc aaacgaccta ctatatcatt ttttgcaaaa
    41101 ctttcatcaa gtacctttgc aacatcaata agtactttat ctcctaacaa gtgaccataa
    41161 gtatcattaa tcgacttaaa ataatcaata tctataatca ataaagcacc atttttttca
    41221 gttgataaat tcaacaaatt ttgtgcagtt aattttctaa tatatgctgc attataaata
    41281 ttggttaaac tatccctttg agccttatct aacaatctat tcttttcctc tttttcagaa
    41341 tcaatattac atattttccc gattacatac attggtattt ttctatcatt ataaattatt
    41401 tttgaagtaa ctctaatcca atgaaaagta tcatcaagca taatagaata catttcagtt
    41461 gttccatttt cttgtgattt tattacatca aaaaactttt tattatattc tttccttatt
    41521 ttatctcttt cattttctat attgccattt tcactttcct tatcattttt atccaaacca
    41581 taataagtct caataccctt ttctggcata gaaattatca atttatcttg cttataatca
    41641 tactcaaaaa agtattcact tgtcatttca tacaactgag tatgtttttt gagttctaaa
    41701 gatatcttct cgttcatact tgtacgagta tgcaaaccaa atgccataaa tccaataata
    41761 caaattaata aactggctac aataaaaata gtctcaattg gattctgttg cataatataa
    41821 agcaacgaga agtcttgtct atatgtagta ttttggtaga caattgattg cattttttct
    41881 gatgaaatac ttataatagc tttattaaat atattcaata attcttgttt atctttttta
    41941 attataccaa aacaaatact ctttgcttta taagtttgag gaactagacg cacattttta
    42001 tacttaggtt gattcatata gtactgcata gaataacctt cgccataagt gtaatctgca
    42061 tagcctttat taacagcttc tatacactct tctaaattat cataccaaac tatattctct
    42121 tcaaactgac cataataatt aatacctttg gctagagcta cacgttttcc atctaaacta
    42181 ttctcattta atttattatt aatcatcata gtatattgag tagaaagaaa aggccgagac
    42241 ataactatat tatgttcacg agagtattca taatcataaa tcattcctgc tacaatatca
    42301 atttcacgct ttttagtcat gttttctaaa tcttcttgag attttacagg cacaagttca
    42361 aattctaagc ctgttttatc acatatatga tttaacaaat caattgatat acctcttaat
    42421 tcacctgtat ctttatctat attttgaaat ggtggtttgt ttaaaagtac tcctactttt
    42481 aatttttctg tctctttaat gtaatcagtt tcttcatcag ataaaaacat ttgattgttc
    42541 tctggtgtaa agtatttttc atataaagta gttgaaaaat atgggtcttt ctgttcaata
    42601 ttattaattg ctgagttaag cttttgagtt aaatttgtac tacctttagg agtaatgaaa
    42661 taaaatggtt ttgatgaaaa ttttgctaca gtacgtacac cttctagtgg gttcatactc
    42721 acattaagaa gtacatctgc tttaccactc tttagtgctt ctagttgctc atcatttgtt
    42781 ttacaatata ccaattcagg tgacataaga ttcatcttac aatactcatc taactcttta
    42841 agcctagtat cagaattttc tattacagca atacggattt ttttcacatc ttgtgaactc
    42901 attatgttat caatatctgt attttcatat aatgcttgta gtactgtatt tgctactcca
    42961 taattattcc ctgcataatt atatattttt tgcattggct cattgtataa catacctccc
    43021 attatatcaa tttcaccatt ttctaacatc ttcattaatt ttgtaataga ttcatttata
    43081 tctccaggaa cttgaacaaa ttcataattc catccagtat actgtgcaat ttctagtaaa
    43141 tattcatatg tatacccaaa atagttacct tgctcatcta tttcagttaa acctttttga
    43201 ataggataag caacacgaat ggtacgatta tcattaccta tagcgttgat accaaaagaa
    43261 aatatgcaag aagtgaatat agatgtaatt acaataatta ataaaagtaa tttttttaaa
    43321 ttcactacac aatcctccat atagttaaga tttacagtat aaattactgc ataaacttgt
    43381 agacatgtaa aaatagatta gtatataaaa ggatatataa atctacttag aaatttaaat
    43441 atccttaata tatacaatat atttaaatta taactcattt atatgtctat tacaacaaat
    43501 ttaccctgct aaatacctac tctatatccc ataattttac aagttgtagt gaagtttaag
    43561 ttctatctca cctcaaattt agcagtgttt ctatttacag ttcttttata tttcacatct
    43621 ggataaccca atataaatga agtgataaca gcttcgttct cgctcattcc taacagttct
    43681 tttatctttg gctctacatt tgatgccata acaaaaaatc cattataaca aattcctaat
    43741 ccttgagaat aggccataag ttccatatta gatgcagcca gtcctccatc tacataagca
    43801 cttccaccta gagacatatc tcctacaact accataagta gtggggcatc ataaaataaa
    43861 gaatcatttc cgttctcttt atatcttttg tacattttct taaatgtatt tttatagata
    43921 gaacgtacag ggtcattgtc atcagtatct aatgccaaat tataaagacc ttgtattgcc
    43981 agttctttca cttcttttag cttttctttt actaatatgt atcttatagg ctgtctatta
    44041 ccacctgttg gtgtgtatct accagcttcc actatgtttt ttattttttc ttcttctacc
    44101 tctatatctt tatattgtct tatacttctt ctaaatttaa taaaattcaa taacttttcg
    44161 ggttctaatt caaaactttc acgattgtat tctattactt catttttatc aaatccttgc
    44221 atttctattg catctgttgg gcaaattgcc atacagtgac cacagttaat acagagaata
    44281 tttttaacct ttgctttatc atccttaact tttattgcat ttacaagaca gtctgattca
    44341 cacataccac agcctacaca tttttctaaa tttatgtcta tcattccaaa ttattcctcc
    44401 ttttaaaaaa tttactttag tataaaacaa atagttgtct aagtcaattt ttattttttt
    44461 aacaatatac tagccttaac tacactttaa tggagaaaaa tatacataaa ttggaactta
    44521 aattagaact tattcaaagt aaaagataaa agaagtagat gtctaaaagt gaacttttta
    44581 gttaattaga tattctttat tgtatgaaat caagtggata tttatcattt caacaataaa
    44641 aaaggcttac ctctattttg gatatgtccc tgtcaagtag acagactaaa aaaaggctat
    44701 ctttatgcac tgagatagcc ccttttccca actactattg tttatcttaa tattagtcaa
    44761 taaatttaat ttgctataac ctgtaagtta cattttaatt tgatgtaact ttaaattaca
    44821 tttttaagta atatctttaa attatattct taaaatatat cattaaacta cattttaatt
    44881 aatctaaaaa ctatatctta attaatctaa gaaacttaca ttataatctt ttagtttccc
    44941 attatcatat acaatctttg cactaaagat atttccagtc ttagcccaat ttaagaacag
    45001 cctgtcacct tcccacatat ttaaatcgaa tattttatca ttatcaaccc aaattaaatt
    45061 tccttcttta caatcattta aatctttttc agataattca ccttcaaact catctgagaa
    45121 atacaaaaac atataccaat cttcttcatc tttaaatttt ggaaaagtta tcaacccttt
    45181 atatgacaat gatttaagag taagaccagt ctcttctttt acttctctaa ttacacattc
    45241 ttctggggtc tctccttgtt caaactttcc tccaactcct acatacttac cttcatgtat
    45301 atcatctttc tttttatttc tgtacaacat caaagtcttg tcatcttttt ctatataaca
    45361 aatagttgta agtttcatgt atctcgcctt gctttctctt tatattctca actaattatt
    45421 ttcagcactt tcaagcacat cacttatatt cttcattgca ttaagagaaa gctctgcaaa
    45481 ttcatcaaat ggaatcccta tatcttctat acttctcatt gcatctctat ttacatttga
    45541 agcaaatctc gtttctttca ttcttttaat aacagactta gtctttacac tggtaagttt
    45601 tttatctgga taaactaaag ctatagcagt tataaaccca gttatagggt ctgctgcata
    45661 tattgctttt tccattaggc tagttcttgt aactcccatt ccatcatgat gaccaagtat
    45721 tgctctatac atttcttcgt caccgaagtt ttctttttta agcagttcta ctgttgttgt
    45781 agcatgtcct tcacatattt ctcctggctt tcttccaact atatctgaat ccaaatcatg
    45841 taaaagacct gccactgccc actcttcttc tttttctggc tctagtcttt tggctaattc
    45901 tctcataaca gcttcaacag cataacaatg ttttctcatt ctatcagttt ctaaatactt
    45961 aaataaaatt tctaaagctt cttctctcat tttcaccaat ccccctgttt tttcacatat
    46021 atgatatttt tatatattaa tacacataaa ttcaagtttt tatatatatt catgtatatt
    46081 tttcatgtta tatctattct acacctttat agtagtgtcc tgcaactgtt ccaatttcat
    46141 ctaatttctt atacaagtct gtagcctttt ttccaagttt ataattatta ctcaatacct
    46201 caatgtgagc ttcaataacc tttttaacca tctcactatc ttcaactgta aaatctatcc
    46261 taaatacatc tattccaatt tcctctaact catatagatt gtccaacata caagtaacct
    46321 tcgaattgta aattgtactt ctacagaata tatcttgtgt tatcctataa cttgcatccg
    46381 taaagtctct taaagcataa ctactttcct tacatttagc aactctcttg tcctttttac
    46441 aatctctaac aactactccc ataggacagt attctgtaac catcatagga gcatatccat
    46501 atattactgc ttcaatttct acatctgtat attttaaagt ttgtttaatt tcatttaagt
    46561 ttagttcttg tgacaaacaa actgtacttg ctccctcttc tttgaagtgg tttatacttt
    46621 cactattgaa tgcatttaag tagcaatcta tatttaagtc ttttttctta aagtattcca
    46681 tagagcccca gttaccaatt tgaaccttat taattccttt tatattatcc aatatctcaa
    46741 attgcttgta ctctttattt ctaacaatcc ttggtgctga atagattaat tttttgttag
    46801 tgactgctgt attatagtgg ttcttattca aagtatctat tttacttgta tttgacaaag
    46861 tatctatgtt atttgtattt gaacccatta gttctttagg agtatctaaa gacgaagaag
    46921 tatctaaatc catagaaata cttgaatcta tagaaatatt tgaatctata gaaatacttg
    46981 agaccatttg taaagctttt gataatgtat ttatatcttc ataatagatt aaatctacat
    47041 tataatttaa tactgcttct aattgctcca agttcttaac tttaactcta atcttaggaa
    47101 ctgtatcaag ttttttctgt ttatttactc tatttggctg gtattttaat ctattcttct
    47161 taaattttct atcttttatc tttattcttt cttcatctaa aagctcaata caatcccttc
    47221 tcatttgatt taacacactt ataggcatac ttacaccttc atccaggtca atttctatct
    47281 cttttaactt atatggtgta tttccaagct tttgaatttg tgtttctatt ttttctttac
    47341 ttaaagccac ctttatagct ttttcaacta ttttgtctcc ttctaccacc gatttatttc
    47401 cacaaaaatc acttataaaa agctctggct ttttacctag tttaatactc acttttgcac
    47461 gtatattagt ttttatgaac tctttatctt gctgaaatgt agcttgtact ctatccatca
    47521 attcgctgtc agaagtctta tatataagct gatttctctt tgcttctcca acaaaatcta
    47581 attctatcaa atccccttta tgtgctattg tagttatctc tccatccttt attattcttc
    47641 caatagtacc tccacctaag ttaattccat cacctttctt aagcgtattt tctagcatta
    47701 ctctaagtct tttgttcttt ctattataat ctaaaacttt tccaatatat agcccttgat
    47761 tattaggtct attagagttc attatatcct taccaacttc acctaatata tatccttttg
    47821 taaactttct attaaatatg gtatacaaat tatttattat ttcctcagaa atacttattt
    47881 ttttcttatc tacaaattca ttaatcgctt ctctatatcc tgaaaccaca gtagctacat
    47941 actctggctt tttcattcta ccttcaattt ttaaagataa tacacctgct tcaattattt
    48001 tatccaaatc ttctatagta cttaaatctc taggactcaa caaataatct ccattacttt
    48061 ttactacttc tcctgtattt atatctatca actcatactt ttgtctacat ggctgtgcac
    48121 acctacctct atttccagac ctattgccta tcatactact cataaggcat tgacccgagt
    48181 aacatacaca taaagcccca tgtacaaaaa cttctatatc tacagttgta ttttcacaaa
    48241 tccattttat ctcatcaaca tttaattctc ttgctaaaac aactctatca aaccctacac
    48301 tctgaaggta ttttacatct tctaaggaat gtgctaccat ttgagtgctt gcatgtagtt
    48361 caaagtcagg taatagtttt tttataagtc ttgccattcc tatatcctgt actattaaag
    48421 catcaatatc tatatcgtat aaaaatttta catactctac aaaatcttct atttcatact
    48481 gttttatcaa tgtatttaca gtaacaaaga cttgcactcc ccttatatga gagtatttaa
    48541 cagcctcaat cagctcattt ctatcaaagt tatttgcaga tgctctagca ctaaagtctt
    48601 taccacctaa atacacagca tttgctccgt tttgaactgc tgcttttaat gaatcaaaag
    48661 agcctactgg tgcaagtaat tctatttttt tcatattttt ctcctctatt tatacttgtt
    48721 aggttaatat aattatatct ataacttaaa tatttgtatt aaatttatat atttcttact
    48781 atattttaaa ttcttcaatc aatttatata ttagttattt atatttggtt catttgagtt
    48841 aacatataca ttatttacta tatttagtat atttctatta acttatatat ttattactgt
    48901 attttaaatt cttcaattaa tttatatact gcttactaaa tttaaaacat tttaattaat
    48961 ttgtacactg tttactatac ttgaaatact tctattaatc tatatattgc cta
//
LOCUS       DAEOTL010000021        47966 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEOTL010000021 DAEOTL010000000
VERSION     DAEOTL010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.021"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            246..1556
                     /locus_tag="KRH82_001506"
     CDS             246..1556
                     /locus_tag="KRH82_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBG8654793.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            1654..2571
                     /locus_tag="KRH82_001507"
     CDS             1654..2571
                     /locus_tag="KRH82_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBG8654794.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            2587..3396
                     /locus_tag="KRH82_001508"
     CDS             2587..3396
                     /locus_tag="KRH82_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBG8654795.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            3454..5202
                     /locus_tag="KRH82_001509"
     CDS             3454..5202
                     /locus_tag="KRH82_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBG8654796.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            5464..6486
                     /locus_tag="KRH82_001510"
     CDS             5464..6486
                     /locus_tag="KRH82_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBG8654797.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGVTKEAPETSRRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDREILS
                     ALIEKR"
     gene            6491..8797
                     /locus_tag="KRH82_001511"
     CDS             6491..8797
                     /locus_tag="KRH82_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBG8654798.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            8769..9884
                     /locus_tag="KRH82_001512"
     CDS             8769..9884
                     /locus_tag="KRH82_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654799.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVRIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            9902..11320
                     /locus_tag="KRH82_001513"
     CDS             9902..11320
                     /locus_tag="KRH82_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBG8654800.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            11335..12543
                     /locus_tag="KRH82_001514"
     CDS             11335..12543
                     /locus_tag="KRH82_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654801.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLNLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(12617..14005)
                     /locus_tag="KRH82_001515"
     CDS             complement(12617..14005)
                     /locus_tag="KRH82_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBG8654802.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            14346..15680
                     /locus_tag="KRH82_001516"
     CDS             14346..15680
                     /locus_tag="KRH82_001516"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBG8654803.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPSIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNISK"
     gene            complement(15822..16739)
                     /locus_tag="KRH82_001517"
     CDS             complement(15822..16739)
                     /locus_tag="KRH82_001517"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBG8654804.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            16947..17831
                     /locus_tag="KRH82_001518"
     CDS             16947..17831
                     /locus_tag="KRH82_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBG8654805.1"
                     /translation="MKVLKKITILLLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            18044..19885
                     /locus_tag="KRH82_001519"
     CDS             18044..19885
                     /locus_tag="KRH82_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBG8654806.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            20190..20897
                     /locus_tag="KRH82_001520"
     CDS             20190..20897
                     /locus_tag="KRH82_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654807.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            20891..22201
                     /locus_tag="KRH82_001521"
     CDS             20891..22201
                     /locus_tag="KRH82_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654808.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            22318..23001
                     /locus_tag="KRH82_001522"
     CDS             22318..23001
                     /locus_tag="KRH82_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654809.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            22994..25381
                     /locus_tag="KRH82_001523"
     CDS             22994..25381
                     /locus_tag="KRH82_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8654810.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            25661..26803
                     /locus_tag="KRH82_001524"
     CDS             25661..26803
                     /locus_tag="KRH82_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBG8654811.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            26822..27346
                     /locus_tag="KRH82_001525"
     CDS             26822..27346
                     /locus_tag="KRH82_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBG8654812.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIIFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKNCIK"
     gene            27446..28264
                     /locus_tag="KRH82_001526"
     CDS             27446..28264
                     /locus_tag="KRH82_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8654813.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEVVSQLFAKKLEESLSPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            28342..28653
                     /locus_tag="KRH82_001527"
     CDS             28342..28653
                     /locus_tag="KRH82_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBG8654814.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(28830..29513)
                     /locus_tag="KRH82_001528"
     CDS             complement(28830..29513)
                     /locus_tag="KRH82_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654815.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIHNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(29606..30247)
                     /locus_tag="KRH82_001529"
     CDS             complement(29606..30247)
                     /locus_tag="KRH82_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654816.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(30421..32424)
                     /locus_tag="KRH82_001530"
     CDS             complement(30421..32424)
                     /locus_tag="KRH82_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBG8654817.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFNSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(32577..33215)
                     /gene="recX"
                     /locus_tag="KRH82_001531"
     CDS             complement(32577..33215)
                     /gene="recX"
                     /locus_tag="KRH82_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBG8654818.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            33491..34180
                     /locus_tag="KRH82_001532"
     CDS             33491..34180
                     /locus_tag="KRH82_001532"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBG8654819.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            34181..34753
                     /gene="yqeK"
                     /locus_tag="KRH82_001533"
     CDS             34181..34753
                     /gene="yqeK"
                     /locus_tag="KRH82_001533"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBG8654820.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            34870..35220
                     /gene="rsfS"
                     /locus_tag="KRH82_001534"
     CDS             34870..35220
                     /gene="rsfS"
                     /locus_tag="KRH82_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBG8654821.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            35574..37994
                     /locus_tag="KRH82_001535"
     CDS             35574..37994
                     /locus_tag="KRH82_001535"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBG8654822.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVETFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            38830..39498
                     /locus_tag="KRH82_001536"
     CDS             38830..39498
                     /locus_tag="KRH82_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBG8654823.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            39538..39618
                     /locus_tag="KRH82_001537"
                     /pseudo
     CDS             39538..39618
                     /locus_tag="KRH82_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(39981..40253)
                     /locus_tag="KRH82_001538"
     CDS             complement(39981..40253)
                     /locus_tag="KRH82_001538"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8654824.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(40484..40905)
                     /locus_tag="KRH82_001539"
                     /pseudo
     CDS             complement(40484..40905)
                     /locus_tag="KRH82_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(40924..41022)
                     /locus_tag="KRH82_001540"
                     /pseudo
     CDS             complement(40924..41022)
                     /locus_tag="KRH82_001540"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            41305..42675
                     /locus_tag="KRH82_001541"
     CDS             41305..42675
                     /locus_tag="KRH82_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBG8654825.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            43034..43192
                     /locus_tag="KRH82_001542"
     CDS             43034..43192
                     /locus_tag="KRH82_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654826.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   43478..43973
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=43478..43506
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(44115..44212)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            44438..44821
                     /locus_tag="KRH82_001543"
                     /pseudo
     CDS             44438..44821
                     /locus_tag="KRH82_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(45010..46005)
                     /locus_tag="KRH82_001544"
     CDS             complement(45010..46005)
                     /locus_tag="KRH82_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBG8654827.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(46126..47754)
                     /gene="aspD"
                     /locus_tag="KRH82_001545"
     CDS             complement(46126..47754)
                     /gene="aspD"
                     /locus_tag="KRH82_001545"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBG8654828.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEGLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
BASE COUNT        18283 a         5539 c         7943 g        16201 t
ORIGIN      
        1 aaaagctgta ggtaaaaatc tacagctttt tattattgta gattaaaaag atgcgtaatt
       61 aaattttaaa ttggagaaaa taaattggaa ggtatcaatt ataaatatta gaaacgttgt
      121 catagaaaaa aactatatta aaaaaaagta catagaaaaa actgattaga caataaatac
      181 atgctttgat aatattttaa atggagtgaa aatgtgtaga attataatga aaaaagaaaa
      241 taaaaatgaa aaaagaaaat aaaatggagg gaataaaagt gggtatgtta aaaaaattat
      301 gttcactagc tatggtagca attatgacta caacacttat aacagggtgt tcaagtggaa
      361 atggaaaaga ttcaaaaaag gatggcgaaa aagaaaaact agttctttgg atgccaccag
      421 tagaaaataa tatgaaggaa gtttgggacc ctattttaga taaatttgag gaaaaaaata
      481 actgtgaagt agatttacag ataattcctt gggataatta ttctgaaaaa tttgcaacag
      541 ctataagtgc tggcgaaggt ccagatgtag gatatatgta tgcagaaatg tatccacagt
      601 ttatagaaag tggagcagta gaagatttga ctaactatgc aactaaagag gataaagagc
      661 aatctattta tataaaaaca tctgaaatga tgggtggaat gtatggtatg ccattccaag
      721 cagcaaatcc aggggtatta tactataaca aggatatttt agagaaatta ggagaaaaac
      781 ctcctaaaac atgggaagat tttaaaagaa tttgtaaaaa agcaacgcaa gatactgatg
      841 gtgatggaaa gatagaccaa tggggattag ctcagggatg gggagctaaa acttttggta
      901 acttaaactg gaactggtat ccttatttat ggcaagctgg tggagatata tttaatgatg
      961 atttaaaatc ggttaaattt aatgataaga gtggtttaga agcagctaag ttcttaaaag
     1021 aattacaagc atatgtgcct gaagattctt tatctaaaga tagtaatgaa atgatagaaa
     1081 gtgtatttgg accagggaaa gcagcattta caataatgtt atcttctgct gcaacaagtg
     1141 tatttgatga atcattcccg gatttaaatt ggggatttgt aactggacta gaagataaga
     1201 aagcagcaac ttttggagca gtagaccatt tatctttaat gtcatctgcg aaaaataaag
     1261 aacttgcata caagttaata caacatatgt taagtgttga atcaatgaca gaatttcata
     1321 aagcaatacc aagagcacca ataacaaaag gtgaaccata tcaaggtgat gaaagattca
     1381 aagaaatggt ggaaaatgac aaaaatgtat atagaccatt agtagtagga cctcatggag
     1441 ttgaaatata tgaatattta tggaaagaac ttcaaactat gatttcagga gataaaactc
     1501 caaaacaagc gttagatgat gctgcaaaat attcaaatga tttattagca caataaaagt
     1561 ttaaagctgt aatatgttgt aaaggacttt acagattaaa attagcattg tatttataaa
     1621 tacaatgcta atatttatat tggagaggat aaaatggaaa acttagttag agagtttgaa
     1681 gaaaattcaa aaagaaaaaa aacaaaatta aatattaaac catatatgta tatattgcca
     1741 ttgggaataa ttttagtggc gttttatgtg ataccaataa taatgtcaat atactttagt
     1801 tttacaaagt ataatattat tagtccagct acttttatag gtttagaaaa ttataaaaaa
     1861 ttatttacag atgaaacatt aaaagtatct attataaata ctattaaatt tactgttgtt
     1921 gtagtacctt gccaaactat attatcattg attttggctg tttggattac aggaaaagga
     1981 aatagtaaaa tagcttcatt tgctaaaggt gctatattta taccagtatt atcatctatg
     2041 gttttgatag gtatggtatg gagggcttta ttgaatggag aaggttctat tatatatcag
     2101 gtattaggtg cctttggaat agaatcatct aaacttttag gagatagtaa gacagcatta
     2161 cctacactta tgtttatatc tatgtggaaa aatatagggt atttcatggt aatttatatt
     2221 tcagctataa tgaatttacc aaaacactgc tatgaagtag cgaaggttga tggggctaca
     2281 aaacttcaag aatttataaa aataactgta cctttattaa aaccaactac aataatggtt
     2341 gtatttttag ggtcgatatg gtcattacaa gtatttgact taatttatac tgtgacaggt
     2401 ggaggtccag gtatatctac tatgagtata gttatgcatg catttaactt aaactttaaa
     2461 aactttaatt ctggatatgc aatgactgta gcaaacgtat tatttttgtt aatagcagta
     2521 gtttcgattt tacaaaataa gcttgtaaga cgagacaatt cagattttta gaaaggtagg
     2581 tataatatga aaacagcaag aagattatta agtgatggtt tacttttatt tatagcgtgt
     2641 gcaagtttgg taccttttat atacatgttg ataatatcat tgaagataac atataactca
     2701 tatagtttgg atatatcttt ttcaacagta acccttcaaa actatataga tatttttact
     2761 aaaaaaggat ttgcacaata tttttttaat acagcaatag tatctttttc aggtgtatta
     2821 ttaaatttag tatttagtac attagcagga tattcttttg cgaagatgga ttttaaaggt
     2881 agtgataagt tatttttatt tatgataatg actttaatta taccttccca agttacaatg
     2941 ataccactat atataataat gaaacactta ggatggataa atagttatct tgcacttatt
     3001 atgccaatac caactgcatt tggcgtattt ataatgagac aagctatttt aggagtacca
     3061 aaagagttat tagaatcagc aaagatagat ggttgctcgg attttagaat tttaatacaa
     3121 atagtgttgc ctttaattaa accagcatta attacactag caatatttac ttttatggga
     3181 gcatggaacg agtttatgtg gcctcttata gctacaacta aagatgcaat gagaacatta
     3241 acagttggat tatctactct taagacattc cagataacta attatggaca gatgatggca
     3301 ggggctacaa taacattttt accgccattt attttctatt tgattttgca gagtaaattt
     3361 gttgaaggtg tgtctttgtc tggtataaaa ggttaaatag tctaatttaa taatatataa
     3421 agaaacttat ataaatatgg aggaatttaa actatggaaa tttcatatgt actgaaagat
     3481 tgcacattca aacacaataa atattcagtt atagaagctg aaacttggaa agataaggat
     3541 ttggatattg tagtagctaa aggtgaaaaa tttgcatttc aaattatgtt aaaagcaaca
     3601 gaagaattta attgtacaat tgataaaagc agtgctatat catggaaagg cctaggaaat
     3661 agagtaaggt tagcattaaa tgtgcctaat agtttagaaa ataattttag tataaatata
     3721 ttaggatatg ttcaagatga tacaaaggca tttgtgaatg atgctatttt aagggataaa
     3781 gatgtgttag tagagcaata tttgcctcaa acattttgga ttgaaggtca agtaccagaa
     3841 gattttgaag aaaataacct tgatataggt attgatatat ttaaaagctt tggatatgaa
     3901 gacgaagaaa aagtttgtac aattgatgtt cctgtaaaag taagaaatgt tgtgctaaag
     3961 cctttagatg aaagcaagtt ctttttagat ttatggcaac atccaagttg tttagctaga
     4021 atgtataaag ttgagttatg gtctgatata cattttgaaa tagtcgataa ctatttaaaa
     4081 gaattagcat ctttaggaga aaaagttgca acagttatag tttcagatta tccatgggca
     4141 gggcaaagtt gttataaagt ttataaaaat ccatcaaact tatatgaata taacatggta
     4201 agtgtatcaa aaggattgga tggaaagatt aaatgtaact ttgagagtat ggataggtat
     4261 ataggcatag ctgataagta taaaatggct aaggagatag atttatttgg tctattaggt
     4321 aattggtgtg ctggtgagtt tggaaatcct gtagaaggtt ataaggaccc tataagagta
     4381 agatattttg atgaaaagga taaagtattt aaatttataa acaatacaaa tgatttaaaa
     4441 gaatatatag gattagtatt aaatcattta atagagtgtg gattatggga cagagtaagg
     4501 attatagctg atgaaccaaa taatccagaa gtagtcaaag agtgtataga atttataaat
     4561 tctactgtag gtactcatca agttaaatat aaatcagcaa ctcacgacca aaacttttta
     4621 gacagagcta aagatgaaat tgatgatatg tcaataaatt taaaacttac tatacaaaat
     4681 tataaagata tagaaagtct taagaaaaaa atcaatgaca agggtgggat attgacttgg
     4741 tttgtatgct gttttccaga gaaaccaaat agttttttaa gttctccttt tgtagaaaat
     4801 agaataatag gatggtatac ttattacttt ggtcttgatg gatttttaag atgggactat
     4861 aatttatgga cagaagaccc ttggaaagat tcaagttaca aattccctat ttggaaagct
     4921 ggagatatgt tctttgttta tcctggaaaa gatttaaagc cagttagaag tgtcagaatg
     4981 gagaatttaa gatttggaat acaggacttt gagttattta caatgttaga aaaagaaaag
     5041 ggaagagagt atatagaagt tgagcttatg caagaattat taaataaaaa agaaaatgct
     5101 gaaattaaag gttttggtga catagaacta ggatattcac ttgataattg gggatatgat
     5161 aaagttaaaa aatatgtatt agagttgtta gacagagtat aaaaaatata agagtgtctc
     5221 aaaatgaact ttttagttca tgaggcactc tttttgtatg aaatcaatat agtttcattg
     5281 tttcaacaat gaaaaatagg attatttcta ttctaagaca gccctttagt tttttagttg
     5341 tattcaatgt tttaaaacta actataaacg ctataaagtt tataaatgac aataattata
     5401 tataacatga tgtactttaa tttgctataa tagggattga ataatattat atggaagata
     5461 acattgtttg gggggattaa tataaaaaga ataggtatta ttataatgtt ttttttaagt
     5521 atatctttta ttggatttta tcttgtaata agagataaca gtgatacagt taagatgcaa
     5581 cgagggataa atataggtaa tgcactagaa tcacctaagg attttccgtg ggatgtaaaa
     5641 atgtcaaata agttttttga tgatataaaa gatgcaggtt ttgacacagt acgtatacca
     5701 gtaaggtttt ctgattatac gtcagattct gataatttta aaattgatga agaatttttt
     5761 aaaaagattg ataaatatgt agattatgca ttggataaag acttaatagt tgtgttggat
     5821 ttacaccatt ttgaagaaat tatgaaagaa ccaagagttc ataaagaaaa gtttttaaaa
     5881 atatggcaac agatagctaa taggtatcaa aaatatgata aaaaattggt atttgaatta
     5941 ttaaatgaac ctaaagaaaa tttatattca cagttactaa acgaatacat tgaagaagca
     6001 ataaagataa ttagaaaaac taaccctaaa agaactatta tagtaggacc atataatttc
     6061 tatcaaattg attatttgaa tgaattaaat attcctaaag attctaatat agtagtttcc
     6121 tttcactatt acgagccaaa tgattttgca tttcaaggaa atatctatca taagggattt
     6181 gagcacttaa gcaatattac ttgggaagga acaaatgaac aaatggatta tttaaaaaaa
     6241 aggtttgata ctgtggaaaa ttgggcaaat aaaaataagg taaaaatctt cttgggtgaa
     6301 tttggagtaa caaaagaagc accagaaact tcaaggagag cttgggtaaa agctgtaaga
     6361 gaagaagctg aaaaacgaaa cttttcatgg gcttattggg agcttgcttc tggatttggt
     6421 atatacaatc aaattgaagg gacttgggat agagaaatat taagtgcatt aatagaaaag
     6481 aggtgatttt atgaagaaaa attcaaaaaa gatacttata actttaacta ttattactaa
     6541 tatagtatat atattgtgga gaatttttta tacagtacct aaagaagaag ggatgtttgc
     6601 cctaatctgt gccataatac ttctttttgt agagataatg ggtatgatgg aaatgtttgt
     6661 gcattattat ggtatgtcaa atattgagta ccctgaaaaa ccaatcataa gtgaagaact
     6721 ttatccacat gtagatgtat tcattgcaac atataatgaa tctgttgatt tggtgagaaa
     6781 aactgtaaat gggtgtattc atatgcagta tccagataag aaaaaggtac atatatacat
     6841 atgtgatgat ggaaatcgtg aagaaatgtg tattctagca gaaaaaatgg gtgtaaatta
     6901 cataactaga actgaaagag aaggagcaaa agctggaaat ttaaataatg caatgcaaca
     6961 tacaaattcc cctttgattg ctacatttga tgcagatatg ataccaatgc atgacttttt
     7021 aattgctaca gtaccatact ttttgaaaaa tgagcaagct aaaaaagatg gagaaaaaga
     7081 ggagtatgaa aaggttggtt ttgtgcaaac tccacagagt ttttataatc cagacttgtt
     7141 tcaatttaat ctgcactctg aaggaaggat tccaaatgag caagattatt tttacagaga
     7201 cattcaattg gctagaaata ggacaaattc tgtaatttat ggtggtagta atacagttat
     7261 ttcaagggaa gcacttgaag aagttgatgg attttatact tattctatta cagaagattt
     7321 tgcaacaggt atcttaattc aaagtaaggg gtatagatgt tatgctattc cagaagtaca
     7381 tgcatcaggt ttatctccga cagatttaaa aagtcttatt aagcaacgtg aaagatgggc
     7441 acgtggatgt atacaaactg gtagacgtct aaatattttg tttaggagag gtttaggttt
     7501 ttggcagaaa ataagttata tttcttcaat tacttattgg tatgcaagta taaaacgctt
     7561 tgtatatata atggcaccta ttttattttc tgtgtttaat gtgattgtag taaaatgtac
     7621 gttacttcaa gtattggtat tttggttgcc aatgtatatt ttaagtagtt tatctcttaa
     7681 aatattttct caaaatataa gaaatactag atggaccaat atatatgaaa ctataatgtt
     7741 tcagtcttta atgccagcag taatacttga aacgtttgca atatctaaaa ataaattttc
     7801 agtaacaaat aagagtaaat tagaagaaaa tagaatgtat aagtttttac agggaatacc
     7861 ttattttatt tacatggtct tatctatcat aggaatttta aaaatgtttg tagcaatatt
     7921 taaaatgagt tcaatgacat attcagttgt attattttgg ttgattggaa acctttttaa
     7981 ccttgttatg gctacattat ttatatcagg gagacagcag ttaagaaagt ctgagcgtta
     8041 tattgctgaa attgatttta agttaaagca aaattcttat gttctttctt caaaaacaat
     8101 tgatatatca gaaaatgggt ttgcattttt gctagaaaat ccagaatata tttccccaga
     8161 agaagagttt gaggtagagt ttagagaaaa atctggaaat gaaatgtata tagctaatat
     8221 gaaagcaaag attgttaatg ttgtggaagt aaattcaaag tggaaatatg cagcttatat
     8281 tacacatatt gaggatagtg aaatagataa ttggatgtgt attgttcacg atagaatacc
     8341 tactttacca atgacaatat ctaatcaact aggtttcttt gatgatttgc aaattaatgt
     8401 aaaaaaacgt attgaaaaaa ctagaacatt atcacgaaga agtccaagaa tcaatatgaa
     8461 ttttcagatg gatataaaaa atacaggtaa attaagaata gtgaatttta attatcaata
     8521 tgtattatta aattttgaga ataaaagtat ttatcctaaa gaaatagcat tggaaattaa
     8581 tgaaaatatt gtgttagaat gtgatttgtg tgagggtaaa attgatgaaa gaggtatctt
     8641 atataaagta aataacattg acagcataat gcaaaatttc tttttaagag atgaaatgat
     8701 ggattggata ttacaaaata agacaattct tgtttcaaag cctagtgaaa agaaggaaaa
     8761 aagtatagat gagtttgaac ccatggaata tatttaggag agatgaaatg aagactttaa
     8821 aagtgttttt ttgttctaca aaatatctta ttttggtgtt tatttttttt ataaatacta
     8881 cttttataag ttcagcaaca agtgataaaa ttttagattt atcctttaaa aagatagaga
     8941 ctgacttaag ttctaagatt acatatgagg atacaggtgt aagaatagaa acggatagtt
     9001 ctaaaagcga taaggaacgt tatttatata tttaccaaaa tataaaagaa aattggagca
     9061 tgtataataa tttttatatt gaaattcaaa ataaaaataa aagttctcag agaataaatt
     9121 taagcataca aagtaaaaat atgcttgaat ttagattaaa agaaggtagt gaagtatttt
     9181 tagaaggtaa aaatataata tattcagata aaataaaaga aggatgcata gaagtaccag
     9241 gtgaatttga aggcaaaatt tatgtgaact ttaatagcct tataaatgag gaaagtaatg
     9301 ttgtgctgga ctcaaatatg ctttcaaaca ttgttagttg gggaattacg tttattccat
     9361 ctgatgaaga acataatatt gttattataa aaaagatatc tttattgtct gaagagaaat
     9421 taagattttt aaataatatt aaaataattg gcgatgaaga agtacaaata ccagtattgg
     9481 gtcaaagtat aagtcagtat gaagtattag gtcttaaaag tgattctaaa attaagtact
     9541 ctcttatggg aaaacaagat aatgtgagca tatctcaaaa aggtaaatta acattaagta
     9601 ataaagccaa acctggacaa attattttac aagttaatgt tgatgataag tttaaaattg
     9661 gaaagaaaat aacattaact gagtcttgga gtgttaataa aaaagataag gatggtgttc
     9721 catatacatt agtatatcct gagcaatcac caacagtaca agatatgaaa aaaataaact
     9781 ttatgaataa catcataacg tttgttcgaa ttttatttgt atctctagta ataatatgct
     9841 ttggaatata tttatattgg aaaaaatgtt caaaaactaa gtaaagagag gaggttagat
     9901 tgtgttattt tcaagtttaa tttttttatt ttatttttta cctataactt tggttttata
     9961 ttatgtattt aggtttaacc gaacgataca gaacatgata ttgcttgctg ttagtttatt
    10021 tttttatgct tggggagagc caaaatttgt tgttatcatg atagtttcca taataatgaa
    10081 ctatatattt ggtttactgg tagatagata tagggaaagt aaaataaaag taaaagtttt
    10141 tttagttttg atgtgtgcat acaatatagg tgttttattt atatttaaat atctagcttt
    10201 tgcgctaaga aatattagtg aacttattag tactgaattg actataccta gtattgtttt
    10261 acccatagga atttcatttt ttacatttca gggaatgtct tatgttatag atgtatatcg
    10321 tagacatgga gaagtccaaa agaacccttt ttatgtggga ttgtatatag catttttccc
    10381 acaattaata gcaggtccta tagttagata tgagagtgtg gcagaacaaa ttctcaatag
    10441 aaaagaaact tggaataaat tttctattgg tacttgtagg tttataacag gtctaggtaa
    10501 aaaagtatta atttcaaata acatggctat agtagcagac tatatttaca ctatgaatag
    10561 tcaaggagaa atagctgcat cacttgcatg gcttggttca atagcctata ctctgcaaat
    10621 attctttgat ttttctgctt attcagatat ggctataggc ttaggtctta tgtttggttt
    10681 taaatttgaa gagaacttta attatccata tatatcaaaa tcaattagtg agttttggag
    10741 aagatggcac atttctttgg gaatgtggtt taagagctat atatactttc cgcttggagg
    10801 ttctagagta gcaaataaag atattatgat tagaaatatg tttatagtgt ggttattcac
    10861 tggaatatgg catggagcag aatggacatt tgtaatttgg gggattttaa actttgtttt
    10921 cctaattata gagcgattta taatgtttga aaagattgaa aatcacaatt ttataaaaca
    10981 tatttatgct ttattagtag ttaattttgg atgggtattg tttaggtcac ctaatttaaa
    11041 agaagcatat aattatttta aagctatgtt tggaggcaat ggagctatat ggagtgatta
    11101 tacatatatg tttttaaaag aatactgggt tttctttata tttgcattta tttttagtgt
    11161 acctattgca aagaaaatca ataagtttgt tgttgaacaa gctaaatata gtatgatatt
    11221 taacgtattt tatccaatct cagctatttt attgtttttt atttctgtga catatttagt
    11281 aactggaagc tataatccat ttatttattt taatttttag ttgggaggaa aagtatgaat
    11341 agatttttta aagtaagatt aataactgca attatgttct taattatttt attcgctttc
    11401 tctatcttta atgtttgtta ttctggaaaa gatacgatac aggaaataaa aaattcaata
    11461 gctgaaaaaa gtagtttaaa agatacaata tcatctattg ataatacagt gaatgacaaa
    11521 gtaatataca aaaatacgtt cattgaaact tatggctatt tacaaaaatt aatgggtaaa
    11581 aatgagtttt caaaatttag tgttgtaaaa gatacttctg gaaagatgca ttatacatat
    11641 tttgctaaag ctccaaatcc agttggtgtg atagcagata gggtaagaaa attttctgat
    11701 gaaatggaaa agcaaaacac taaattggtt tacctaatga ctccagataa gtatataaaa
    11761 ggagtgacaa aatttcccaa aggaatacct tattcttata gtaatgagac agcagataat
    11821 tttttaaatc aactaaaaaa gtataatgtg gactatattg attttagaga aaatatttta
    11881 aagagtggta ttccaaaaga tgatttattt tttaaaacag accatcactg gaaagtagaa
    11941 acttcttttt gggcatttgg agaattagtt gagcaactta ataaaaaata caatatgaat
    12001 ttagatgaaa atcattatta tagagataag gacaattata attcaattgt atatcctaag
    12061 tcatttcttg gttctatggg aagaaagact ggtatcttat atggtggtat agatgatttt
    12121 acattaattt atcctaaatt taagactaat tatacttatt atacagattc taaatctcaa
    12181 aaatttgaat taaaaggaag gtttgaagag agtttaatat tatcatatcc ttttaatgca
    12241 gaccttaatt taatggatgg tcaatcagat aagtatttta catatttatt ggggaacaga
    12301 ccattagtta aaataaaaaa tatagaaaat ccagatggat taaaagtgct gtttgttaaa
    12361 gattctctaa ttgtaccaac agcagcattt ttttcctctg tttgttcatc tatagatatg
    12421 atagacccta gatattatga tggagatata ctagaatatg caaaatccca tgactatgac
    12481 tttgttttta tatctgtata tccccaaaat cttacaaaag aattttttcc gttttgtgag
    12541 taaatttcta aaaaagtttt ctgataaaat aaatggctaa ctggtaaaaa gttagccatt
    12601 tattttgagt gttattctaa gaaatatttt ttttactaaa tacttcttta tctatttttc
    12661 caagtgattt tcctacagta attgatgata ccatagcacc attaacattt atcatagtac
    12721 gtcccatatc tagtataggg tctattgcaa gtataccacc aactaatgga aaataagaac
    12781 caagaccaac tccagagata acaactgaaa cggccattgt agcagttcct ggaagaccag
    12841 ctattccaaa cgaactaatt gttataacaa ttaacaacat aacataaaag ctcatatcca
    12901 tgtttactcc agccatattg gcaagtgtta cagccattaa agcaggatat atacctgcac
    12961 aaccattcat acccatattt gcacctaaac ttgctgtaaa gcttgataca ccctcatcaa
    13021 ctccgtgatt ttgtactaga ctttctatcg ttacaggcaa tgttcctaaa ctagaacgtg
    13081 aagtaaatgc cagaagtaaa gcttcagttg aattttttat ataagtaatg ggatttagac
    13141 catttaaagt tataaaaatt aaatgtatga taaataatat tgcaactgat atataaagag
    13201 ctaatataaa ctgtaaaaca gatactattg aactaatacc ttgtgaagtt attgtatttg
    13261 caagcagagc aaccacagca taaggcataa atttaataac agtcatagac acacttacaa
    13321 ttattttgta agatgcttct ataaaatcta taaatggttt tattgtctca aaatgttttt
    13381 tacttaatct ctttattgag gtagctataa atgtagcaaa tattattgta gctacaatat
    13441 ttccatttgc catagccatt acaggattag atggtagtaa tcctcttaaa gtatccacaa
    13501 gagagtttat ttctttaagt tcttgatttt caactaaagt aggcatatta gctcctacac
    13561 ctaacttcat tatatttgca acgataattc caacaattgc agctatagca gtagtagcaa
    13621 gaagcatacc taaagattta aatgtcagag ttccaagatt gttatctttc atatttataa
    13681 ttacttttat aatggataag aaaactaaag gtactactaa catttttaat aagtccataa
    13741 atccagaacc aaataggcta taccacttac ttacttcttg tagccaaatg acttgagttg
    13801 tatcattagg gaaaccagca aaagcttgta ttatgattcc caatatgagt cctagtactg
    13861 tagcatatat tgttctcaat gaaaatttta tttttttctt ttcaaattgt ctaacaataa
    13921 agaacgtacc tagaagtaat attatgaaaa aaattgtttt aaaatctgta atcataagaa
    13981 attgtgataa aaatgaactt tccaatattt ttctcctttt atttaaaaat aaatttttct
    14041 aagtttaaat gatatcaata tattaaaaaa atgtcaatat tatatcacaa tttacttaaa
    14101 tagagtaaaa caagttgatt ttgaaaaatg tgattaagta cagaaaaata gggtataata
    14161 aatgtttaaa gaatttgaat tgtggtaaga aaataaaaaa tagcttttat aagatttgat
    14221 ttcaaattaa aatgtgttaa ataaataact aaaaattatt ataaaaaatg ttttcataga
    14281 atatatatca aatgaaaagc ttaaaataag tgaagaaatt aactagacat caaaggagag
    14341 ataaaatgag agtaataata attggtggtg ttgcagctgg tatgagtgct gcagcaaaat
    14401 taaaaagaat aaaacctgag tatgaagttg ttgtttatga aaaaactgaa atagtatctt
    14461 ttggtgcttg tggattacca tactttgttg gtggattttt taatgatgct gatgaattat
    14521 tagcaagaac accagagaaa cttagagaag ctggaattga tttaaatata tttagagaag
    14581 tcgttgaggt tgatagtgaa tctaagaaaa taaaagtaaa aaacataaaa acagatgaaa
    14641 tatatgaaga ttactatgat aaattgatga tagcaactgg agcaagaagt attatgcctt
    14701 ctataaaaaa cataaaattg aagaatgttt ctacattaaa aagtttatat gatggagaat
    14761 atctaaaaaa acttttaagt aatgaagata ataaaagagt gacaataata ggagctggtt
    14821 ttatagggtt agaagcagtt gaggcatgta agaaattagg taaagatgta gatgtaattc
    14881 agttagaaga tagaatattg ccacaagtat ttgataagga gatgacggat gtattagaag
    14941 aagaaataaa tagacataat gttaatttgc acttagatga aatggttgta gaactttgtg
    15001 gagaagataa agtagaaaaa gttataacaa acaaagggga aatagataca gatgtagtaa
    15061 taattgctac tggcgtgaga cctaataccg agtttttgtc aaatactaat ataaaaatgc
    15121 taaaaaatgg agctatagta gttgatgagt atggaagaac ttctgtagaa gatatatact
    15181 ctgctggaga ttgtgcaact ataaagaata tagtaagtaa tgaaaatgta tatgttcctt
    15241 tagctactgg agctaataaa ttgggtagga tagtaggaga aaacctagca ggaagagaag
    15301 tatcttatca aggttcacta tcttcaagct gtataaaaat tatggatatg gaggcagcat
    15361 caactggaat tacagaaagg caagctaaag atttaggcat aaatgtcaaa tctaaattta
    15421 tttctgatta taatcaaact cattattatc caggaagaaa taaaatatat gtaaagctta
    15481 tttatgatgc agatacaaaa gttattttag gcggacaagt ggctgggttt aaggatgctg
    15541 tccaaagagc aaatgtattg gcagctgcta tctttggaaa aatgaccaca agtcaacttg
    15601 gaatgttaga tttatgttat gctccaccat ttgcaagaac atgggatgtt ttaaatgtag
    15661 ctggaaatat atctaaataa tatttagatt atagctaata tagttgacaa gcaattaagg
    15721 gaatgaattt acctaaacta tttttatcat ggtaaaattc attcctaaat ttttattcca
    15781 aatttttatt ccaaattttt agaaataagg attccattaa attattcatc aaaatttaaa
    15841 cgcaagctta atctatcttc tccaagaata gtattttcaa aaacattagt agcattttct
    15901 aaatacatac taggtatgtc taaagaagga ctaaaatgag tcagtaaaag ttgtttgaca
    15961 tttccaagtt ttgcaagatt agcagcttct ctaaaagtca tatgtttgtt tctaacagct
    16021 tttgatatat ctaaatcatc accatacatg gcttcacata taaataaatc actatctttt
    16081 atgaaatctg gtattgattc tataggtctt gtatcggttg taagacttat cttaactccc
    16141 tttcttaatt ctcctaagac catatctgga gtgtattgtt ttgaatctaa aactatattt
    16201 tgaccttctt ggagtttgtt ccataatatt ttaggaactt cgtttttagt tgccttatct
    16261 atatcaaatt tagggtttct tctaaaatta aaactgtatc ctaaacactc tatagagtgt
    16321 tctaaactga ttgttgaaat ttctaaattt cttaaaactt tattatctaa agaaaaattg
    16381 ccttgagggt tttctataat ttttaaagtg tatggtacat attctactaa atttctcata
    16441 gaacgtatac aatcgactat tccaactgga ccaactatag ttaaatcact tgtacgacca
    16501 ctattcccaa ttgttgataa aagtcctaaa agtccaaata tatggtcacc atgtaaatgg
    16561 gttatacaaa tcaagtctat atctttaaag ccacattttt ttagcttcat agatacctga
    16621 gtaccttcac cacagtcaat tagtattttt ctacctttat agtttataaa tacagaggat
    16681 agaaatctgt ttggcatagg tacatttcca ccacatccaa gtaaagttaa atctatcatt
    16741 ttttcccctt tctaaaatta acacaaatct gttgtttgtt tttattatga tatcctatta
    16801 taattatttt aacattaaat ataacaataa atgtgtattt gagtcaagaa atattgtcaa
    16861 ataaagtttt tatataacaa tgtataaaaa tttggaggac aaaaagtgaa aattatattt
    16921 agaagtattt aaaggaggaa aatttaatga aagtattaaa gaaaattact attttgttat
    16981 tgattacatt aactttagtt ggttgtagta acggagaaga gaaaaaagtg gttgaaggtt
    17041 ctaagaaaac tcaaaattct aaaaaagatg aacagcctat aatagtgcat aaagatgcaa
    17101 atatattgaa agataggtat gagccaccaa aaggatttaa aagagttgat gtagaaaaag
    17161 gtagttttga atcatttctt aggaatacta agctaaaaaa ttatggagag aaagtaaagt
    17221 attatgatgg aagaactaag gaatcaaaag gtatttatga tagtgtattt gatgttgata
    17281 ttggaaatag agatttacat caatgtgcag atgcaattat gcttatgaga gcagaatact
    17341 tgtatcagaa taaactatat gatgaaataa gttttgattt tgttgatggt tttaaggcga
    17401 agtattcaaa atgggcacaa ggatatagaa tttcagtaaa agatagtggt tcaagctggt
    17461 ataaagcaac tgaatattca acatcttatg agagtttcag aaagtttatg gatatagtgt
    17521 ttgcatattc aggaacgtta tctcttgaaa aagaattgga gcctgtaaaa gttgaggata
    17581 tgaaaatagg agatgtgttt atagttggtg gaagtccagg acatgcaagt ataattatgg
    17641 atatggcaga aaatgaaaag actggtgaaa aggtatttat gatagcccaa agctatatgc
    17701 ctgcacaaca aacgcaactt cttattaatc gtaaaaatcc aaatttgagt ccttggtata
    17761 gtttagattt tgaaggtgat ttgacaatac ctcaatggac ttttaaaaga gaccagttga
    17821 aaagatttta aaataataat tttatataat aaaagaaaaa tatagatgtg aaaaaatgta
    17881 attagattaa aactaattgg atatggacaa aattaaattg atagataaat attaaaaatt
    17941 acactaatta atcttactat agtttaatat ttatctaaaa agttttatgt aaaatataaa
    18001 ttttatatta aagctaaaac taatttgagg aggctaattt atattgaaga ttagaaggta
    18061 tttaattttg gtaattataa ttctaattac aacaagtcag agttttattt cttatgggct
    18121 agagcgattt gaagaaataa ccatttttca cactaatgat atacatggaa gatatgctga
    18181 aggtgatgac catatacaaa taggaaatct agccacattg aaaaaagaaa ctccaaactc
    18241 aattttagta gatgcaggag attgtttgca tggacttcca atagtaaata tggatagagg
    18301 gaaaagtgca attgaattaa ttaaatgtgc tggatatgac tatattactc ctggaaatca
    18361 tgactttaat tatggaaaag atagactgtt tgagttatct aaaagtgcta atttaggaga
    18421 gaatacttta aaatttttat catcaaatat ttttgaaaat ggaaaaaaag tttttgatag
    18481 taatgatata aaagaaatag atggaataaa aataggattt tttggactct caacccagga
    18541 aacaaagagc aaaactggat ttaaaaatgt ggaaggatta gagtttaaaa atcctataga
    18601 aagtgcaaca gaacaagtaa atgaattaaa aggaaagggt gccaatgtaa tagttgcaat
    18661 atgtcatatt ggtacaaata gtttaagtaa gccaaatagt atagatatag caaatgaggt
    18721 tcaaggaatt gatttgatta ttgatggaca cagccacact aagtttgaaa atggtaaaca
    18781 agtgggtgat acattgattg taagtgcagg acaatattta gaaaatattg gcgagataaa
    18841 actaactttg gatactaatg atgtagaaaa tataaaaata gaaaataaat cagttagatt
    18901 aattggaaaa gaagaagcat taaagtataa gcttgactcc gctgtaagta aaaaggttga
    18961 tgaaataaaa gaacaacaag aaaaaatatt agataaagtt ataggggtaa ctacaaatac
    19021 tctagatggt tcatatgaaa atgtaaggac aaaagaaact aatttgggta atttaataag
    19081 tgacatttta ctagataaaa ctaaggctga tatttcttta tttaatggag ggaatattcg
    19141 agatacgata gaaaaaggca atataacaag aagagatatt gtagatgtat ttccttttag
    19201 caatactata gttaccaaag aacttacagg agcacagatt aaagatgtat tggagcatgg
    19261 agtaaaactt tatccagaaa aaagttcagc ctttttgcaa gtgggaggaa tttcatatta
    19321 ctttaatcct aaacaaaaag aaggcgaaaa aataacaaat attcaaaaag aaggaaagcc
    19381 attagattta aataaaaagt atgtagttgc aacgaatgat tatatagcat caggtggaga
    19441 tgaatttcct tgtttttcaa aagagccagt actaaaggaa tttggaaatt tagagagtgc
    19501 agtcattgaa tatatagagt acaaaaaaga aatatcaaaa aatgtagatg gaagaattgg
    19561 tattaaatct aaagatgagt taataagcaa gaatcatgag agtgatttga tattaagtga
    19621 aaatgaaaaa aatatcaatg ataatgaaga gaatctatct aataatataa aaagctctga
    19681 tagtgataaa aataaaagct tagataaaac aagtgctaga gaaagttcta atctaggaat
    19741 atctaaaaga gaagctaaag aaaaatctcc taaaacagga gatttaggtt tttcaaatag
    19801 tataattata tttatagttt caagtacatt gatatgttta ttgaatttta atcaaaaaga
    19861 gttaaaggat aaaaagtcaa aataaaaatt aatgagcaaa aattagtaga tagtaattta
    19921 attttagata atagtaaaca gcaaaggaaa ttagttatat aaatactaat ttcctttgtt
    19981 ttatgtttta acatgattac ttttaaataa aattgtattt tatgaaaaat aattacacta
    20041 aatggcatag tattatgggg atttttagtt tttattcaag taaatgaaat catattaaca
    20101 acttctgata tatttacaaa ttgataaaaa aatgatttta ttagtatgat ataatttagc
    20161 tagtatatat gatgatggag gatataggga tgaataatat attacttttg gaagatgaca
    20221 aatctttaaa tagaggaatt agttttaaat taaaaaaaga aggatacaat gtttttagtg
    20281 catttggtat agaagaagca aaaaatattt tcgcaaaaga agagatatgc ttaattattt
    20341 ccgatatagg tctacctgat ggtagtggtt ttgacttttg tgaggagatt agaaagaaaa
    20401 gtgatgttta cataataatg ttgacagctc ttgatgaaga ggtggatatt gtcacaggat
    20461 atgatttagg tgcagatgat tatatcacaa agccttttag cttgatggta ttaatatcaa
    20521 aagtgaatgc gcttatgaaa agagtaaata cagtaaaaaa ttatactcta ttagtttgtg
    20581 atgatttatt cttttattat atagaaaata aattaattat aagaacagat gataaggaag
    20641 aagagataat tttaagtaag acagagacaa aactattaaa atatttgatg gaaaattcta
    20701 tgcagacatt gactaaagag caactgttag aatctttatg ggatagtagt ggtaattttg
    20761 tagatgataa tacgattgca gtaaatataa gaagacttag acaaaaggtt gaaaaaaatc
    20821 catctgaacc taaatatata aaaacagtaa gaggggttgg atatatgtgg ggagaaagga
    20881 gtataaaaaa atgctaaaaa atatgaacct caaagatggt ttaagtgtga aagatgatta
    20941 tataatgaga agagttattg tatattctgt tttatctgta ctaatagtaa cccttgtatt
    21001 tatacttttt gaatatagca gattacataa attgtatgaa catcaaataa aaaatactca
    21061 aaatattgct ggaatattga ttgaaaaata tcctaatgat gaaatagata tagtaaattc
    21121 tatttataat tctgattata gtaaggtgtc tactggagaa aaggcattta agaaatttgg
    21181 ctatggattg gaaaataaaa tgtcaaatga taaaaatttt agcttatact taaaatcttt
    21241 ttttaaggaa tcatttttta tttttttaat gatgtttata gtagttatag gtataatata
    21301 ttattttata agatacataa ataaaagatt gagtaaaatt tattttatag tagataagat
    21361 gtcacaagaa aactacttga aggacactac tgagtcagaa gaaactggtt atctagtaga
    21421 atataatgaa tactttaaag aaggcatatt tagtaagata aataactgtc tatatgagct
    21481 taatagaagt ttaaagataa agtttattaa attagaaaaa gaaaaagaaa gtgtaaaatc
    21541 attagtaaca gatatttccc atcaattaaa aactccttta gcatccttaa aattatacaa
    21601 tacattactt atagaagaag aattagaaga agatgaagcc aacgagttct tattaaccaa
    21661 taaggcttct ataaataaat tagaaaattt aataaattct ttagtgaaca tatcaaggtt
    21721 agaaattagc atgataaaca taaaaaaaga agataatgat ataaaaaata ctattctaaa
    21781 tgcagtaaaa agtgttaccc ctaaggctaa gagcaaaagt ataacattaa atttaaatga
    21841 atttaacagt agaattatac cacatgataa aaagtggact gaggagagta tttttaatgt
    21901 attagacaat gctgtaaagt atacacaggt aaatggagaa ataaatatat ctgtagaaga
    21961 aactgctaat ttctttaaaa ttataataga ggataatggc atagggattg aaaaaaatga
    22021 gtttaataat atatttaaac gtttttatag aggttctgct gatgaaattg aatctgtaga
    22081 aggtagtggg gtaggattgt atttaagtag aaagatttta gaagaacaag gtggaaatat
    22141 tatagtttct tcaaaagtag gaatagggag caagttttct ttgtttctta caactatgta
    22201 atattaaatg aaaggaaaat gtaagcctct acatttatta tataagtata aacagctcca
    22261 gaaataaaaa attaataaaa tatggagtaa tataacttag aatgagagga taattttatg
    22321 aaaatactat atactgaaaa tttatcaaag cattatggaa aaggagaaag cttagtaaga
    22381 gctttggaca atgttgactt agaaataaat gaaggtgaat ttgttgcaat aataggaaaa
    22441 tcaggttctg gaaaaagtac acttttgcat atgattggag gtcttgatat acctacatct
    22501 gggaaggtgt atatagataa taaaaatata tttacattaa aagaagaaga acttgctgta
    22561 tttagaagaa gaaaaatagg gtttatattt caaagctata atttaattcc atctcttaat
    22621 gtatgggaaa atgtagtgtt gccaatcggt ttagatggta gagaagtaga tgaatctttt
    22681 ataaaagaac ttttaaaatc attaggactt gaaaataaac acgacgtttt accaaataca
    22741 ttatcaggtg gtcaacaaca aagggtggca atagcaagag cattagctac aagaccagct
    22801 ataatacttg ctgatgaacc aactggaaac ctagattcta aaacgtctga tgaggttatg
    22861 agtatattaa aatctatgtc taagaagtac agtcaaactc tagttatgat aactcatgat
    22921 gacagtatag cccaaatggc tgatagagtt atattcatag aagatggcag ggtgtcaaag
    22981 gttggtgata aaaatgatta atactactaa aatagcaaaa agtaatttaa agcaaaataa
    23041 atcaaaaagt attctaataa taattactat aatactttca accttaatgc tttcttctat
    23101 tggaatttat attgttgatg caggagcata tcaaaaagaa aacactataa agtattcagg
    23161 taattatcaa ggtatattag caaatgtaga tgaaaaacag gctgatatat tgagtaatca
    23221 tgcagatgtt gaattaactg gtgaaatgaa tggagtaggt gttgaaaaac tggaagatga
    23281 ttcaaatatt tctctagcat acatgaatga agatgctttg aaattaaata gttttgaatt
    23341 tatcaaagga aaattgccat caaaagagaa tgaaattgtg ttagatagtg gagctttaaa
    23401 ggcacttggt tataaaaata aagatttagg tgaaaagata aaaatatctt atgatgacta
    23461 taaaaatgat aaaaaaattg aaaaagagtt cattataagt ggaatcttaa aaactagcga
    23521 aatatctgaa gcaggtaaat attattatgc tattatatca gaatcatata tgagaaatac
    23581 tagagatatg tcacaagaag attttaatat ttatgtgaaa tttaatgata aaagtaattt
    23641 atcaatagag caagcaaaag aaaaattaga taaaattgct aatgatatag gactggatac
    23701 tattaatact gctgtaaatg aaaattatat aaatgcttta aaaccagata tggaaacgat
    23761 tatgggtgga gtttttgtag ggttagtaat tgtattatct agtattttag taatatacaa
    23821 tatattttat atttcaatag ttacaaaggt tcaagaattt ggaaaactta gagcaattgg
    23881 tgcaactaag aaacaaataa aaaatatagt gtttaaagaa gggttcatat tagccggaat
    23941 agcaatacca ataggaataa ttttaggcta tgtacttgca aatattataa taaaatcatt
    24001 tatggatata gatgtaaaat catcacgatt accagttata ttatcggttg tggtaataag
    24061 ctttatatct gttgttttat cacttttaaa accaatgaaa gtagcatcaa aagtatccat
    24121 tgttgacgca gtaagatata caggaaataa aataagtaat aagagtaaga gaaaaggata
    24181 taaaaatata aatctaaaga gattatcaca tgccaattta gaaagaaata aaaaacgtac
    24241 ttacatgaca ttggcatcac ttatacttag tggaactata tttataacag tatcaactgc
    24301 cttagaaagt tttgatgctg agaaaatggc aagagaacac tttccttatg atatagaagt
    24361 tagactatct ggttatgaaa tgaacagtga taaaaatcct aaagataatt tgaatatttt
    24421 acaaatggat aatcctctaa gtaaagattt ttttaatcaa ataaagaaca tggaaggaat
    24481 taaaagaata gaatctgcaa gaagtgtaaa aattggtatg gaggactatg atgttgaatt
    24541 taagtatgac cttttacaaa gtataaatga aaatgatgta aaatcattaa acaagaatat
    24601 aatagatgga aaaataaatc ttgaaagact tcaaactgga gatgaaatag taattactca
    24661 tgttgataca gcaaaagaaa tgggagtaaa agcaggagat aaaataagat taactttata
    24721 tgatggagat aaaaagataa aaaaagaatt taaagttcaa gcaatagcta tgggggttcc
    24781 aagttttggt atagggaaag attttataga tagaactttg aaatacgatt caactagtag
    24841 cttgggaata tatacagaag aaggaaagta tcaagaaatc aaagatagta tcaagaagat
    24901 tgctaaaaat aatggatttt tagagactga ctttatagat agtagaattg agtcaaataa
    24961 ggctactatt tcatttataa agataatggg atatacgcta acaggcataa taggtgtgat
    25021 tggatttatg aatcttgtca acacaatgat aactagcata gttactagaa aaaaagaact
    25081 tggtatgctt caagctattg gtcttactaa taaacaatta gtgaaaatgc ttaattcaga
    25141 ggcaatgtat tacacttctg gaatgatgat aggaagtatt ctatttggag gtatattagg
    25201 gtatattgct gttatatttc taaaaaagac tggattatct tatgcaacat attctttgcc
    25261 aatagtacca atcttgttga tgattgtgtg tattcttata gctcaattta taacaactta
    25321 tttgatagga cgaagtttta ataaagaatc tcttattgat agagtaagat acagtgaata
    25381 aaatgcaaat atttatggtt agtttaacta gcaaaaaaca tataaaaaaa tatagttaaa
    25441 gaaattcata attaaatagg ttaaagcata gtacagagca aacaatttaa acagatgttt
    25501 gctctgtatt ttattatgta atcaataata tatctaatat actgatatta ttcatgttag
    25561 aaaatgtacc ggtacaattc taaaaaagta taaaattgta ccatataaaa tgaaaatttt
    25621 gtataataat cgtatagaaa ataaatagga gctgatatat atgaataaga agattaatta
    25681 tgcaccagga ccaactgaaa ctagggaaaa tgtaagatta gcaagagcag aaaaaacaac
    25741 aaatccagat atagatattg attttgttga attttataaa aagacatgcg agaagtttgg
    25801 taatataatt ggaacaaaaa acgatgttta catattgagt ggtgaaggaa tattaggtct
    25861 tgaagcagca tgtgcatcac ttacagaaaa aggagataga gtacttgtaa ttgataatgg
    25921 tatatatgga gaaggtttta aagattttgt aacaatgtat ggtggggagt atgtgctttt
    25981 ttcaagtgaa tatactaaaa gtatagatat tgatgaattg aaagcatttt tagatgagga
    26041 tagtaatttt aaatatgcaa cagtagtgca ttgtgatact ccaactggcg tattaaatga
    26101 tgtaagcaaa atatgtccat tacttaaaaa atatggaata ttaactgtag ttgattctgt
    26161 agcaggtatg gtaggagaaa gattaagtgt agatgaatct aaaatagata taatattagg
    26221 tggttcacaa aaagctattt ctgcaccagc aggacttact atagtcggaa taagtcaaga
    26281 tgcaaaaaat tgtataaaaa atagaaaaac tgatgtaata ggtttttatt gtaatttaaa
    26341 tatatgggaa ggctattatg aaaaaaaata cttcccttat acaatgccaa taagtgacat
    26401 aatggggctt gataaagcac ttgataatat attagaagaa ggaatagaaa atgtattaaa
    26461 tagacatgaa aagatagctt atagtgttag aaaatctatt gaggaatatg gtctagaact
    26521 atttttagaa gaaggatatt ctaatacagt cacagctata aaagttcctg aaagtatagg
    26581 agctttagaa cttactgatt atatgcttaa aaattataat acacttgttg caacatcact
    26641 aaatcaatat atggatacta ttttaagaat aggtcatatg ggagagaatg caaatctaaa
    26701 taaaatagaa catgtactaa atgttttgga taaaagttta agtgcactag gattcaaagg
    26761 aaatggaaat ttgttaaatt tatttaataa gtattatttt taatagatag ggggatatag
    26821 tatggaagtt acagctaagc aaaaatttac aacgaaagac atggtggaaa cctcactatt
    26881 aatagcatta gtatttattg caactaaatt tataaacata agattaccaa tatctataaa
    26941 tggtgggctt gtgcatttag gaactgcaat gttgttcata tcagcaataa tatttggagg
    27001 taaaaaaggt gctttatcag gggctattgg tatgtcactt tttgatttga tatctgggtg
    27061 gactttatgg gcaccgttta cctttatagt tagaggagtt atgggttatt tacttggaaa
    27121 gattgcatgg gcaaatggta ataatgggaa taatttttta atcaatgtaa taggaatatg
    27181 tgtctcatca atttggatgc tatttggata ttatgtaaca gaagttatac tttatggtaa
    27241 ttttatagta cctcttactt caataccagg taatttaatg caagtattga taggtcttat
    27301 aatagcgctt cctatttcta aggtattgaa aaactgtata aaataaatat aaagtgaact
    27361 aaaatttatg atagcataaa ttatactgta taatattagg atggagtaca taattaaaaa
    27421 attttagtat agaggttagt tcacaatgtt atcagttaca agatattcaa tcaaaaatgt
    27481 tcgtttaaag ccgtgggtaa agtttatttg gtattttgag acaaaatcaa atatactgtt
    27541 aaataataag ttacttccga cagacagtat agatattatt ctcaatcttt ctgatgttat
    27601 ggaatataaa attgaaaatc aagactatac tgctagtaat atgcatttta atggaataag
    27661 ggataaacat ggatttatta ttcaacatgg aaatatacgt gttataggga tttcttttta
    27721 tccatttggt ttatatccat ttttaaagat accaatttca gagtttaaca gacaaattgt
    27781 tgacttagaa gtagtatcac agctatttgc aaaaaaattg gaagagtcat taagtccaac
    27841 acaatcagta gaaaaaattg ttttatattt agaagaagta ttattatcca tattagaaga
    27901 agatttaatt tcaaataaat atgtaaagct tctaaattca tttatatatg ttaatagata
    27961 tagcaatata aaggcatttt gtgatgatac aaatataaat attaaaacat tggaaagaat
    28021 ctgtttaaaa tatacagggt atacacctaa gattttaaag agaatttaca gatttaaaat
    28081 ggcaagtaat caacttattt ataattataa agatgatgaa ctttttgatt ttatttatga
    28141 aaatgagtac tatgaccaag cacactttat aaaagaattt aaaaaatttt cagggacgtc
    28201 accaattaaa tttattggtg agaataagac gattaaagaa aatataaagt acagctattt
    28261 ataattatac tgtcgatttt ttacaatacc tccaatttat tttttgatat gatataggaa
    28321 aataaattgg aggttttaca tatgaaaatt attacagaaa tagttgagtt taatgtggaa
    28381 gaaaatttat caaaagaaga gtttatagaa attgtaaatg acttagaatt aaaatttcat
    28441 tctattcaat ctggttttat tgatactgag cttttatatg atgaaaagtc tcaaaagtgg
    28501 attatgatac aacattggga atctatagaa gacctcaaga gtgcttctag taaaatgttt
    28561 aaagattctt caactgagaa atttagaaaa gctttaaaga atcaaactgt taagatgaat
    28621 ataataccac aaattaaaag ttggaaatta tagaactgaa tgtaaaagat agttaaatag
    28681 tatcaaacta aattagccaa ataacatttt gtatttaaat tgttatttgg cttttagtgt
    28741 ttattttaat atgagtgtta tatactagaa aaaccaacaa actgttagag tgtggattat
    28801 cataatgtca tattcgggag ctaaaagtct taatactgat ttgccaattg gtcaatccat
    28861 gcatgtccat ctggatatgc tgttattaaa gcatttacaa gccaatccct ttgctcttgt
    28921 gataatagtg ggactgttac atcgaagtct ttttgataac caagcctatc tatgtatatt
    28981 gatttgcaaa acaaaaccac ttcgggagcc atatatggga tattatctga tgttatcagt
    29041 ctggccttat ccatatctct tataattctt tgattttggg aaaaaagaaa ttttccatct
    29101 ttctgtggat tatgtatcaa ttcaataaaa tcgaactgta actgttcgtc acactgtata
    29161 ttcattttat agttatcatc ctcgactttt tttaattcaa taaatgagca atcaggctta
    29221 atcgcaaaaa cacaaatttg ctctatatgt tgcttgttaa ggtcgataat aggtcgtaat
    29281 aaataattac ccaagggctc atatatatcc catccttgat taagcatata ctgaatgctc
    29341 ttttctttat ctgtgtcaga aatccatatg tcaatatcac tgtgtgggcg aatatgcata
    29401 ttcgcaaata attctagggc atatccacca catattgaat atgaaaagcc acaatcatta
    29461 aaaaagttta cacaatcttt aattagtttg ttcatagcaa cctccttttg catgtactga
    29521 aataaattaa atttttaaaa ataccaacta aatgtttgtt ttgtgtaaat ataaaactgc
    29581 cgatattaag gcagttttat atttactatt tagaaaattt attaacaaat ttttgatatt
    29641 cacacattat cttatcattc ataaaagaaa tacccataaa agcagcttgc tcaccaaaca
    29701 aagtaaaacg ttctatcatc tgttgtggat tacctggata aactgttgga atacaccatg
    29761 tgtttagaag aaaaccaaac atttgagcag caatctctgg atttttaact tccatagaat
    29821 tatcttgatt tccttcttca atcaatgctt ttatccaagg cacaatatca tttataatct
    29881 catcaaactg cgtagctaaa tacttaggat tacgcaatag tgatgatgac attaaaaaaa
    29941 tgtcttgttt attgtgttgt tcataagcat gaagcaacct atattgtaat ttttctaatg
    30001 cggtctttcc ttcatcattt tttacctcat acccataaaa tccatcatta tacaaccgac
    30061 ttgtgattgc cttaattatt tcgtcttttg atttaaagtg atgataaata gcacctcttg
    30121 aaaggccatc taaattatct acaatgtctt gaatcgttgt ctgctcatac cctttttcta
    30181 agaataactt atgtgaaata tcaagtattt tttgtatagt attatcaggt tctttttttc
    30241 ttcccaaaaa gctcactcct caaaacaatc atttggtatg tttatcttag caaatacata
    30301 atgatttgtc aatgtgtctt tttagcatgt tgaacaggta tattgccatg ctttcattat
    30361 tttatttttt tgccttatac tggactatat ttgcagtttc ctaatatatt tggctcatat
    30421 ttaaatacca ttatctaaaa gcactattgc tgtacgagag gcaataggca ttttagaaga
    30481 aggaggagtt gagttaaagt atacatcata atctcttaag ttttcttttt ttgtgtttcc
    30541 tccaaactct accatatcag tatttaatat cgttttgtag tttgtatttt gaaactttga
    30601 aatatcaact gattgtatta gattagggtg gaaattaaat ataaataaat atttgccctt
    30661 actgtacacc aaaatctttt tatcattatc catatgtata agttcatgac tattttggat
    30721 aaaaatatca ctgtattttg taagttcgag catagattta tcaaaattta ataattgttt
    30781 atactttaag ttgttatctt ctgaaaggct ccattgtctt ctggcatact tatagctcca
    30841 attgttgcct tctcgtggaa aatcaatcca ctcaggatgt ccaaattcat ttcccataaa
    30901 atttagatat ccttcacctg ctagagaaaa agttattaat ttaattaatt taataagaga
    30961 tattgctcta ttgataacat ggttatttga gtttatttcc atattccagt acatttcctt
    31021 gtcagctagc caaaaaataa ttgttttatc gccaactaat gcttggtcat gggattcaca
    31081 atatcctata tttttttctc caggtcgtct agtagtaagt tcataccaca tttttcccaa
    31141 atcccagtct tcatcagata agttagagat agtttttatc caaaaatcag gtactcccat
    31201 tgcaagtcta tagtcaaatc caattccgcc gtcttttata gggatacaca taccaggcat
    31261 tccactcata tcttctgcaa tacttatcga attaggttta atttctttta ttaattcatt
    31321 tgcaaattgg agatatgtta tagcttcaat atctgtattc atactaaaat atttttcata
    31381 actatcaaat gaaactccaa gaccatggtt atgatataac attgaagtta caccatcaaa
    31441 cctaaagcca tcaaaatggt actcatttaa ccaaaatttt atatttgaaa gcaaaaaatg
    31501 tattacttca ggtttaccat agttaaaaag ttttgtaccc caagcaggat gatttccctt
    31561 tgaacctgag tggaaaaatt gatgttcact tccatcaaac tcatttattc cttctaaagt
    31621 attctttaca gcatgagaat gaactaaatc taataaaaca gcaatcccca ttgaatgagc
    31681 agtgtttatg aggtttttta agtcttcagg agtaccaaac ctagatgaga ttgcataaaa
    31741 gtttgaaact tggtatccaa aagatgcata atatggatgt tccataatag ccataagctg
    31801 aatggtattg tatccagctt tttttatctt aggaagtatt ttttcagtaa attcattata
    31861 agttccaata gattcgcttt cagtagacat acctatatga cattcataga ttagtggaga
    31921 agttatgttt tttaagtcaa aattattgtc agtccagata aatggagttt ttggttgcca
    31981 tatttgtcca ttaaatccac caaaatcttt ttgaattact ctttttatat ataatggtat
    32041 acggtcaaat gtttttccat ttgcagtaac ttgtaccttt acctctgatt tgtgaggtaa
    32101 gctattttga ccaggaataa atatttccca attaccagac ccaatttttc ttagaggatg
    32161 agattttcta ttccaattat taaagtcacc aattagtgac aaactatctg catttggagc
    32221 ccattcccta tagaagaatc catcatttgt ctgatgaaat ccatagtaaa gatgagcatt
    32281 tgcaaaagaa ctaaaatctt tatagttttt caatgttttt gatttcatat cctcataatg
    32341 tttcattcgc ttttttatat cagattcaaa tggttgtagg tatacatcaa tatctaaaat
    32401 tttaaatctt ttttgacttt tcattgtatt tctcctccat aataaatatt acatctaaaa
    32461 aataatattt atctcatact atcttctctg tataattgat atatattata taatcctaat
    32521 aaaaagctta agccaccaat gattaatttc ataatttacc tccctagtat ttatacttat
    32581 atatcgtatt catcaaaatt taaaagtttg tttaaaactc ttttaataat atcataatca
    32641 aagcctttat aggaaagatg ttgagaaatt ttttgatata ttttcttttt atcttctttc
    32701 tttactcttt catacctttt ttttgctaga tacatagcat tttcaaattc agtgtccttg
    32761 tctaattcag atactgcttc attgattgta cttctattga tacctttatt atataaattc
    32821 tgcttaattc tgtttttgcc acatttattt aggttaacat ttgtgttaac aattttttga
    32881 gctaatacac tgtcatttac gagattataa cttttaagaa aatctatgac cctctcaatt
    32941 atattttcat caaattctga tgatagtttt tcttttaatt ttttttcaga ttggtcagca
    33001 tgagataaaa tatttaatgc tttattttta gcttttatat acatttcatc atctaaaata
    33061 ggttttaatt cttcttcatt tatttcattc ccctttttta aattaaatgt ataaacaagt
    33121 tctttaaata tagcaataaa aaatttatca tctacataaa tattaactct atcatcattt
    33181 cttttttgtt gttctatttt tgtaattata cccataagtc ctcctttttt atatgtaatt
    33241 atattaacaa aagcaactaa taaaatttaa caaaaaactt atatttgtat gttatatttt
    33301 atcaaaatta agacaaaata gtaaaaagtt atttttatta aaaagtaaag tagaatcatg
    33361 ttaaataatt atttttttaa gtgtttttta gcatataaat ataattatat acccaaaaaa
    33421 acaaattata agctttaaga aataaaaaat aatggtacaa tagtattata acattaaaag
    33481 gagacaaaat atgagaagtg aaaatctagt taagatggca gagttgaaaa atactgaaaa
    33541 actagagaaa tttaatcgcc ataaaggcaa aatcaaaata ggtatattgg gaggtacttt
    33601 tgaccctata cactatgctc atttagcaac agcagaattt attagagata agtatgacat
    33661 tgacaaaata atctttatac catcaggaaa tccaccacat aaattatgta tcactacaga
    33721 taagtatgat agatataata tgacacttct agcaactgaa agcaacgaag attttttagt
    33781 ttcaaaagta gaaatcgaaa gaaagaaaag gacttataca atagatacat taaaatactt
    33841 aaagaaaaaa tacaaaaatg cagacattta ttttataaca ggtgcagatg caatttgtag
    33901 tgttgaagag tggaaagatg taaagaaaaa ctttgagtta gctactttta tagccgcaac
    33961 tagaccagga attagtttgt taaggtcaca agagactata gaaaaactaa ctaagaagta
    34021 taatgctgac attataacag tttatgttcc atcactggat atatcgtcca catatataag
    34081 ggaacagcta aatgaaggca agtcaatacg ttacttagta cccgaaaatg tagaaaatta
    34141 tttatatgaa aataaactat atcaatatgg agatgattaa atgaacttag aaaatattaa
    34201 ccaaagacta aatcaaatgc taccagtggg gaggcttagc cattcaaaaa atgttgcaaa
    34261 atgtgctgaa aaattatgtg agatttatgg atgtgacaaa gaaaaagctt acttagcagg
    34321 aatgattcat gattgtgcaa agtatttaag tgacaaggaa atagaggatt atgtaaataa
    34381 gtatgaaata tatttagacc caatagagga tggaaatcgt tccttgtctc atagtgtaat
    34441 tggggcgtac atatgcgagt atgaatttga agtagaagat gaagatatta taaatgcaat
    34501 caaatatcat acaacaggga gagaggacat gtctctttta gaaaaaataa tttacatagc
    34561 tgatttaatt gaagaaggaa gaaaattccc agttgtagat acattaagag aattagcata
    34621 tggagggaag cttgatgaag cacttttaac ttcttttaat aatactttaa tgtttgtcat
    34681 caataaaaaa gaagagatac atccaagaac agttatggca agaaactatc taattaaaga
    34741 aaagttatta taaaaaagct atataaaggc aaacatatta ataaatttaa atttgactat
    34801 gttacaaaat cgtattaata tgttacaata actaagtgta ttttaattag gaaagtgagg
    34861 aatttttata tgacagtgga acaaatgaca aaaatagcat atgatgccat agaagataaa
    34921 ctgggtcaag atacagttat aataaatata ggaaaagttt ctagtttgtg tgattatttt
    34981 attattacta cagcatcttc tcagagacag gtaaaagcta ttgctgacaa tgtggaagat
    35041 gaattagcaa aactaggatt agagccaaga ggtaaagaag gacaaggaac tcaaacttgg
    35101 gtactccttg attatggaga cataatggtt catgtattta atgaggaaaa tagagggttt
    35161 tataatttag aaaaattatg gaaagatgca ccttatatag atattgacac attagcataa
    35221 acatgataat atatgttatt ataattagaa aatttcaaaa attatattaa attgaataga
    35281 ctagagcagt aaaagattat attttttcag agagttagtg gaaggtgaga actaatatta
    35341 tataactttg aacttactag attaaaatct attctccatg gctggattaa aagctatcta
    35401 agagagtcta tatatgtagt aggctaatta gggtggtacc gcgaagattt atcctcgtcc
    35461 ctaaacgtaa gtttagtgac gaggattttt tattttcaaa gaattatttg gaaattataa
    35521 gtaaataata ctaaataagg tagttataca caattaaaaa taggaggcaa aatatgagcg
    35581 tatataattt taaagaagta gaatcgaaat ggcaaaaaat ctggaaagat aataatcagt
    35641 ataaaatgga tactgcacaa actgaaaaac ctaattatta cacattagaa atgttccctt
    35701 atccatctgg aaaaatacac atgggacatg ttagaaatta ttctataggt gatgttgtcg
    35761 caagattcaa aaaaatggaa ggatataatg tacttcatcc aatgggatgg gattcttttg
    35821 gattaccagc tgaaaatgca gctataaaac atggaataca tccgcataaa tggacaatgg
    35881 aaaatataga agaaatgaaa gagcaattaa atttattagg gattagttat gattgggata
    35941 aagaagttgc aacttcaact ccagaatact atagatttac acaagaaata tttttgaagt
    36001 ttttagagca tgggcttgca tataagaaaa aatcatatgt taactggtgt ccttcttgtg
    36061 agactgttct tgcaaatgag caagttgttc aaggagcatg tgagagatgt aaagcaacag
    36121 tattaaagaa agatttagaa caatggtatt ttaagactac tgaatttgca gaagaattac
    36181 ttaatgactt agatacatta gatggatggc cagaaaaagt taaaacaatg caaaaaaatt
    36241 ggataggtaa aagtacagga gcagatttag tttttgatat agatggaact gataaatcta
    36301 tgacagtatt tacaactaga ccagacacaa cttatggagt tacttatatg gtacttgctc
    36361 cagagcatga attagttaaa gaattggttg cagggactga atatgaagca gatgttgaaa
    36421 cttttgttca aaaaatgcat actatgacag aaatagaaag aacagcagct gatgtagaaa
    36481 aagaaggaat gtttataggt agatatgtta taaatccttt aaatggcaag aaagttcctc
    36541 tatggatagc taactatgta ttagttgagt atggaacggg tgctataatg gcagttccag
    36601 cacatgatga aagagataga gattttgctg aaaaatataa tttagacata attgatgtaa
    36661 taacagaaga taacaaaatg ataaattcag aagaatttaa tggattagat gcttcagaag
    36721 gatttgaagg aataatcgat aagttagaaa aagaaggtag aggaaagaga acaattaatt
    36781 atagacttag agactggtta gtttcaagac aaagatactg gggttgtcct atacctgtgg
    36841 tttattgtga tgaatgtgga atagttccag ttaaaaagga agatttacca gttcttttac
    36901 caacagatgt tgaatttact ggaaaagggg aatctccact tacgacttca aagcaattta
    36961 tgtcaacaac ttgtcctcac tgtggaaaac cagctagaag ggaagttgat actatggata
    37021 cattcgttga ttcttcttgg tatttcttaa gatatgtgga tagcaataat gaaaatgaac
    37081 catttagtaa ggaattagtt aatagatggc atccagtaga ccaatatata ggtggagtag
    37141 aacatgctat aatgcattta ctttatgcaa gatggtttgt aaaggcattt aagagtatgg
    37201 gaatggtaga cttcaatgag ccatttaaaa acttacttac tcaaggaatg gtacttatgg
    37261 atggttctaa aatgagtaag tctaaaggga atacagtatc tcctatggat ataatagatg
    37321 agtatggagc agatactgca agacttttcg tattatttgc agcaccacca gaaagagatt
    37381 tggactggtc agagcaaggt gttgatggat gctttagatt cttaaatagg gtttatagat
    37441 tggttgacga gttagcagat gtggttaaaa aggatgtaga gtttggagaa ttaaattccc
    37501 aagataagga tatgagatat actatacact ctacacttaa aaaagttact gctgatttaa
    37561 gtgaaaaatt cggatttaat actgctatat cagctcttat ggaattaata aatgatatgt
    37621 ataaatataa agagttagat aatataaacg aagcagttat aaaagaaggt gtacaaacta
    37681 tagtaactat aattgcacca tttgcccctc atttaggtga agaactatgg actatgatag
    37741 gtaaagaagg aagtgtattt gatatagact ggcctaaata tgacgaaaaa gctttagtaa
    37801 aagatgaaat agaagttgtt gtacaagtta atggaaaagt tagaggaaaa ttaactgtta
    37861 actcaaatat atctaaagat gagatggaaa aggtagcttt agaagatgaa aaaataaaag
    37921 gattagttga aggtaaaact atagttaaag ttgtagctgt acctaaaaaa ttagtaaata
    37981 tagttgttaa ataactcaaa aatatgaaca aaaatataaa tttataaaat aaatgaggct
    38041 gtctcaaaat agagataagc cttttttcat tgttgaaatt ataaaaatag atttgatttt
    38101 atacaaaaaa atgattaaag aactaaaaag ttcattctta tataccctag ttgttgtttt
    38161 aaatattatt ataattaatg ttaaatcgag ttaatgtatt aagtggtatg taaatcattc
    38221 agtttccaaa gtgttgttca tcaaggaact gctctaagct taaacgaaaa aaatataatt
    38281 attgtatttt gaaatttttt tctatataat gaaaacaggc aaaaaaggtg catatctatg
    38341 ctttatatga aacacccaga caacgaaatt cagattcata taatagctac catgtttcta
    38401 aaaaggaact tgtaaaaaag atagcgtttc aacttcccag ttgattaaaa ttatcagcag
    38461 gaaaacaagt atggtcagca gtggtattct aatgggtgtt gtcgatatat ccaagttggg
    38521 attgtctgag gatgttatca aataacttgt gataggtgca gtagatgtgg agattcctga
    38581 tacggattta ttctcagggg atggttgctt cgggagatat ggagcgtaac cagtttattg
    38641 atatggtaac cattttttgt ctaatttgat gaaagaatcc caagaatacc atacagaagt
    38701 aagacaggaa ttaactggtg gtataaactg ataaaggcaa atttaaaaat tttgatagga
    38761 tgattttaag atttatcttc tattttgttt tttagaaata attgaaatgt tatgaggagg
    38821 tatgtacaaa tggagactgt aacaaataat caatcaggtg tagaaattca actcagtctg
    38881 tttgaagcta tcaaagattt attgttaatt aatcctattt tcttgttggg aattatcttg
    38941 attggtattt tcttagttgt aatattcaag aaaaatagtg atattccaaa ggtaaaaaca
    39001 tctattttat cactggcaat gtattactac ttatgtttaa cactatcaca tattgttggt
    39061 atacctacat tcggtgaata tataagactg tcacagttag gggaaacgtt ctttaatcca
    39121 aacataaatc ttattccttt tagtgatgga tttagtttga gttttatttt gaatatttta
    39181 ctttttgtcc cattaggttt tttatgtccg cttataagca aaacctttga acgtttgaga
    39241 aatacattct tgattggttt tggattatct ctttttatcg aaactattca gctttttacg
    39301 ttacacagag caaccgatat agacgactta ctcacgaacg taattggaac aataataggc
    39361 tatttttgct tcaaactgat tgctaaattg cgaattgtaa aactacattc agatgatgac
    39421 tctatggaac aggattacac agtatgtatt ccgattgcca ttataatagt tgcccttata
    39481 ttaggatttt ttagttaagt tccaaatagc taatttggga attatggagg tcattaagtg
    39541 aataaaatta cttttatatg tttaggtgta aaaagtatgg agaagtcaat taaattttat
    39601 agagatggat taggatttta gattacaaac ttttagttta ccaaggagat agcaaagtcg
    39661 tgtgccaaag ggtaaccatt tggaaatcca gacaacataa cagatagtat gttacctttt
    39721 acaggagcat actatctgtt atattgtcaa catcctattt tatggtttgt gtgtagtttc
    39781 ctgtaaactg aactaaataa ttaaatagaa gctattagaa ttaataataa cagatagata
    39841 ttaataagca taaacaaata gtaaaatgtg tagatataga cgtttttaag tgaaactatt
    39901 ataaaataat tgactgataa tcaactgaca aaacctattt ttttaggttt aactgacatt
    39961 taactgacag tcagttttta ctatttaaat agaagttcgc ttagattgtc ggaagcttct
    40021 ttgtccattt ctttaagtac atgagaatat ctattcatag ttatttttat atctgtatga
    40081 cccaatcttt cagaaacaac tttcatatta gttcccccta aaagcaacag agtggcactt
    40141 gtatatctta aatcatgtat tctaatcttt tttaaattat tttttttgta aaattgtgaa
    40201 acgtttttct tagtgaagaa ggtagaaacg gatttaaatt ggtgtttaga caaactaagt
    40261 tatttctgtt ttccaggata ccttacaatt ttaatttgct ttgtcttagt ttttcaattt
    40321 tcaatttttc aattaattct tttggagctg ataaagctct ttttgatttt ggtgtttttg
    40381 gctctttaaa agatattttg ccattagaat agacaagaat ttgattaaca tttatcagat
    40441 tgttatctaa gtcaacatct gaccacctaa gcccagtagc ttctcacatt cttaaaccta
    40501 gaagtaacat taaaagaata ggtatttcta tattattacc aagtaacttt tctattagca
    40561 ataatacttc ttctctattg tatatttcat ttgtagaata tttttcttta gaaggaagtt
    40621 ttataaaatc acatgaattt tcttgtattt ctcttaatct atacgcttcc cttattacag
    40681 aacttagaaa gctatacctt actttagcac tagtaaaggt agaattatta aagttataat
    40741 ttacaaaagc ttgtactgaa ctaggattta cttctgtgag ttttagattc ttaaaaaagg
    40801 ttctatgtaa tttttaaccc aagattttgt atttgtaaca gtatatggag accaattatt
    40861 tttattcatg tctatatatt tataacatct ttctacaaat gtcatacctt ttggagcaac
    40921 aaacttatta ttatttatag tagactttat ttcaattaaa tgtttttcag catccttttt
    40981 ctttttatag cttccataac ttttttgttt ctttttgcca gtttcttatt ccacatatac
    41041 atagaatttt tcccatcttt ttcttataaa agctgatttg atattcatat atgtacgctc
    41101 cctttataag ttagttttat aaaagaacag ttggactgct ctaattatgt cattatcttt
    41161 ttaattcttt acagttacat tataacacgt atttgtatac acttaaatta acaggaagat
    41221 aaatatcatt aaaggaggaa aagaaaattt aatgtagaat tatgtaagat atatagtatt
    41281 tcatatataa aagggggaga tattgtgaaa ttaaagaaat tattatcact agggttagcc
    41341 gtgtcaatgt ttgctgctgg tcctatatca gctaatgcac ttgatacaat ttatactatt
    41401 caaggaaaag ataaatatga aacggctgct cttatagctg atgaacaaaa ttatactaca
    41461 gctatattaa ttaatgcaga cagcacaatg gctgatggat taagtgcgag tggacttgca
    41521 ggagcaacaa atgcaccaat ttttttaact aagaaaaata acatacctaa tgcaactctt
    41581 aaaagagtag agaaagctaa aaaggtatac ataataggtg gagaaagttc tattgataaa
    41641 gcaacagaaa ctcttctaaa agataaagga atagaggcta aaagacttca aggtagtgat
    41701 agaattaaga caagctataa tgttgcaaaa gaaataaact caattaacaa agtaaataaa
    41761 gttatattga ctaatgcttt taaaggagag cctgatgcaa tgagtgctgc acctgtagca
    41821 gttagagata aagcagctat agtattaact gatggaaaaa gtgttccatt taatacaact
    41881 ggtgtagaaa gttatgtaat aggtggtact tcatcaatga gtgacaaact agttaatgat
    41941 actaattcaa ctagattagg tggagtagat agatatgata ctaataaaaa aatagtaaat
    42001 aagttctata atggcgcaaa agaattttat atagctagtg gtactgattt agtttatgct
    42061 ttagttgctt caccaatggc taaaaataat cctattgtac tagttgatat tggaagtaat
    42121 aaagatatac ttaaaaatgc tgcaaaagtg actgggatag gaaatctaag tgataaaatt
    42181 atgctagagt gtgaaaatac catcaataat attagtcttc cgtcttcaaa taaaaatata
    42241 atatgtggat taaagattga ttttgattca aagcacataa tttggcaaga taaaggaagt
    42301 tatcttgaat gttatgatga taaccttgaa tattatactg aaaaatataa agacccaaca
    42361 gttcctataa atatagaaaa tacaagtaca caaaatttag atgtaacaaa attaaaagtt
    42421 tatggagaag ctaattcaac attatatatg gggcaatatg ctaaaataaa aatggatttt
    42481 aatagtttcg gtgtattaaa gccaggagaa aaatgtacta tttatttaga tataatttca
    42541 ttagatccat caagaagcat gacattaaca ttttcttatg taggtgataa agaaaattat
    42601 aaatatgaac aaggattggc aagtagaata ttattttata acccagatgg agaagatttt
    42661 tttgaatata aataactagt gggtatgtaa attaataagg gttttataag tttaattttt
    42721 ttattttcgt tttatattaa ctatgtggta tgtaaatgtc tcgatattgc tcatatgttg
    42781 agttattata tttagtttca tatgaactat atggatttta aaattaaaaa tacttaaaaa
    42841 catttacttt aatagtaggt gtttttttga ttaaaagaat attattataa tgtaaaaagt
    42901 aataaatagg taaaatatgt aagaattata tgttataata tttttagcaa gaagatgtaa
    42961 tctacaattt atagagtgga gttcatgtat caaaaaatta tcctcccgac gctaagaagg
    43021 gaggtgaata tacatggata attttttaca aggcatacta gcaagtctat ctgctagctt
    43081 aatagtttat atagctagca aactatttag aaagcgtaaa aaaccactca aagcggcaac
    43141 taagagtggt tgggaatttg atttaaaaat cagattccat aaaactaagt aatttctaaa
    43201 ttatgaactc cactctacag caaaatagat tgtagttctt cttgctttta ttatatcaca
    43261 aattggtaca gatattcaaa aataatattt ttatgatata ataaagtcat agaaattttg
    43321 cagtgttcga ttttttgaag aaattaaggc ttaacagttg aaatataagg cattgaggac
    43381 ttgtgataag tgttatcaat tgcactactc atggttcact gcaaatttga gagatttgta
    43441 tatgtgtagg cattggaaat actcaattta ttttggggtt ttatattaac tatatggaat
    43501 gtaaatagta tttcagcaat tttactttta ataactttat cagcgtttta tattaactat
    43561 atggaatgta aattcaattt accgtttttt tcaaatctca caacatcaga gttttatatt
    43621 aactatatgg aatgtaaatc tatcggcttc ttgaaaagcc tcatctgctc tatttagttt
    43681 tacattaact atatggaatg taaatttcat taaatcccca accgaattat ctttcagcat
    43741 ttgttttata ttaactatat ggaatgtaaa tcatgctgat aagaatctct atgaacttcg
    43801 gagggaaccg gttttatatt aactatatgg aatgtaaatt tgggtatttt gctaaaaata
    43861 aagctattaa attagagctt tatattaact atatggaatg taaatcgtat taacacctgt
    43921 tcggcactat cacaataaac acaagtttta tattaactat atggaatgta aattgtatcc
    43981 aaaaaattac aataatcata cgaactgcta atataagcag tcaatatatg tgtacattta
    44041 tccattttat ctctaaacat ataaattatt atccccctaa aaaactttca taaaaacaaa
    44101 aagaacaata tctctttggc aactggctaa cataactcat aagatattta tataagtctt
    44161 agtccctata gctttgcgtc actagatttc tctagttttg ccgatttagt tttattctat
    44221 aactaaataa tacaatagaa ttagttatta ttcaacaaga ttgtttgaaa attgaataaa
    44281 tttataggta tgaacgtaat ttcacactta aaaacagact aaatacgtag aatatataga
    44341 aaaatttacc tgtagttttt gtgataaaaa gctcctatta ttaatttaag ctagataagt
    44401 ttgaggaagt gacataaatt gaaagaagga atatattatg ttgaataaaa aattaccaga
    44461 tgcagaatta aaaattatga aatacatatg gaatactggt tataaaactg taatatcaaa
    44521 agatgttgca gattaaatag aaaaaacata tgcttggaag catacaacta caattacact
    44581 tttagctaga ttaactaaaa aaggtttttt catatcgcag agaattggga aacatgtaca
    44641 ctatagagta ttaataaaag agaaagaata tctcaaaata gagggaaaaa gaatttttgg
    44701 aggtctacat aacaatccat tatcagaact aatttcaaaa ttacatgatg gagaagaaat
    44761 aactgaagaa aaaataatag aaataggaaa ttggataaaa agctggaaag atgaagatta
    44821 ataaataaaa ggtagctact aatataagtg ctaccttttt tcttgtggat aatattgggg
    44881 ataagttgtg gaaaatttgt gtaaaaattg tggataaaat attttgctga catttaactg
    44941 acataagtat tagattttga tttaaaaatg ttgaaatatc aataaataat taaatagaag
    45001 ttattagaat taacaataga ttcctttttc aaagaaatct ttgatttcat caaggttatc
    45061 agtttttcca agtgctaaga taagttttat tctagctttt tgacctggta agtccccacc
    45121 aaatatacaa ccaagatttt ttaaatctct accagaacca aagtaaccat aactatcgaa
    45181 tactctacct gaatgacatc tagaaactat aactacagga agtccttttt ctctagcata
    45241 ttcaactcca gaaagcattt gaggaggaat attacctctg cccattgcct caataactat
    45301 acctttataa ccactatcaa cagcaaatct tataaagtca gcattttctc ctacatatgc
    45361 tttaaataag gcaactttag attctacctt atcagtatct ataattgttc tatttacaat
    45421 atctcttgta aggacaagtt cgttgcagtc aattattccc aatgggccac tagttagaga
    45481 tttaaatgta tttagagaaa gagtatttgt tttagtagct tcagaagcta ataatacttc
    45541 attgtttaaa actacaagga ctccttttcc catagcatct ttggatactg cagtacaaac
    45601 tgatgcagat aaattacttg aaccatcata tccaagttca gaactacttc tcatagcacc
    45661 tgtgactatt acaggtttga tgttgtcaat tgtaaggtct agaaaataag ctgtttcctc
    45721 taaactatct gtaccatgtg ttattacaac acctgtaata tcttttcttg ctaataaatc
    45781 atttacatag tttttcaatt ccatcattct ataaggtgtt atgtgaggtc ctggaatttc
    45841 atcaaaatta aaaacttcaa catctgcaac tttatcaatg ttggtaacca ttgatagtat
    45901 ttgttcacct gataaagttg gtatagctgc tccgacttta tcatctactg tcatagatat
    45961 agttccacca gtaaaaacta tggcaacttt tttcttaata ctcatactat tctctgcctt
    46021 tcataaataa aatttataat tccgatagga ttatatcaaa aaaagtagtt aaggtctaca
    46081 taaactcttt tattcatata atttagatat ttcagtgtaa tataattatt tcttaatttt
    46141 ttgccattca acgatataac catttaatat ctctcttatg gcttttccta tcttagtata
    46201 agcttcatca tatagatttg ctagagatat tctaattgac cattcaggac catagaatcc
    46261 atttccacta agtaaaacta ctgaatagtc attagctaat ttataaagaa catctactgg
    46321 agatgcattt ttacttataa atttaaataa gccttctccg tagtttaatt tagcccattc
    46381 ttcaatatca aattgagtgt aatatgcagc attgtttttg ttttcattaa ttggaagctc
    46441 taaagcttca aataatagtt tttgacgtct atggcagata ctcatattga gttttttgta
    46501 ggcatctact ttgtcaatca atgcaaaagc agagaaaaac gccatttgta cttgctgtgg
    46561 agtagaaaga ccagcagtat ggttgagagc aacaagtctg ctatcagcaa caactctttc
    46621 cataaatgaa aggctagaag ggttaagact catatcactg taacgcttat ctactgattt
    46681 ttttaattct ccagttaaat catttatttt cttatcaaaa acatttttct tatgaagggc
    46741 aaatgtacca agtctccatc ctgtaactcc aaaatatttt gaataagaat atactccaac
    46801 agtgttgtaa ggtagttttg acattaagga tgaaaaatct tctacaaaag ttccatatac
    46861 atcatctgat attatcatta aatctttatt ataattttca attacatcta ttagattatt
    46921 acaagatgtt tcatccatag ctatagaagc aggattatta ggattaacaa cgaataaagc
    46981 tttaatagat ttgtcacgaa gtttctctaa ttcttttttt gtatattgcc atgtgtgagc
    47041 acctttttca tcaacttcat tagcatttat atttaccact ttaaagtcgt aacgaggaag
    47101 gttaggtatt tcaagataag gtgtaaatat tggagtcatt aaggctattg tatctccttt
    47161 ttttagaagt tcatttgcca ttaatgaatc aaatatatag cacatagcag ctgtagcacc
    47221 ttcaacagca aaaatttcta catcaccata tttacctgat atatcatatt tcatttcttg
    47281 aactaggtaa tcgtgtacta ttttttccat atgaggtaac attctatctg gaagtggata
    47341 gttatcacca ataattccat cagctagttc atgaacaaat tcatctccat caaatccaag
    47401 ttcatttata ccaaagttta taatatctct agctaaatat gctccaggca tatctatatt
    47461 ttcatttata aatttaaaaa atctttcttt aatacccttt ttttgaggca ttccagccaa
    47521 atgacctaaa tcccaattag aacgagtttc agtaatagcg aaatgaccaa aagtaaaaaa
    47581 ggcttctcta gcagttgaac aagtccagtt tggatttcca cgacctgcat caagtaattc
    47641 tctgttattt tcttttgcag tgtattttgc aatatctatt aatttgtcct taaattcaaa
    47701 agggcttatt tttccatata tgtttttgat ttctttataa gtatgatttt tcatgttaaa
    47761 ttcctcctta tgtaataagt ttcacatttt tataataaaa taaacaagtt gcaaaaatga
    47821 ttatacttta attataatag gtttatagaa aaagtaaagt atgaaattaa aataataact
    47881 ctatttagcc ttattaaata tatgttaaaa taaaaaatac cttttaataa aaaatgattg
    47941 ttatataaaa taaatattca atttaa
//
LOCUS       DAEOTL010000022        47342 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEOTL010000022 DAEOTL010000000
VERSION     DAEOTL010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47342
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.022"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            44..205
                     /locus_tag="KRH82_001546"
     CDS             44..205
                     /locus_tag="KRH82_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654829.1"
                     /translation="MDNFLIGVLASLTASLIGYIVCLCIKKVKSHSVQESDLDVELKF
                     SFKFKKNKH"
     repeat_region   487..845
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=487..515
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            915..1112
                     /locus_tag="KRH82_001547"
     CDS             915..1112
                     /locus_tag="KRH82_001547"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654830.1"
                     /translation="MNKDIEFIACSMRLKILIQAREDLIENINKYSTKSYEKNIDNYK
                     KLDMIFEDAIKFEAILLSSLK"
     gene            complement(1087..1452)
                     /locus_tag="KRH82_001548"
     CDS             complement(1087..1452)
                     /locus_tag="KRH82_001548"
                     /inference="COORDINATES: protein motif:HMM:NF022172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2513 domain-containing protein"
                     /protein_id="HBG8654831.1"
                     /translation="MKRDLELIRDILIKMEESDADRMSISDFMTDVYDERTISYHLQL
                     LLDVGFIEATPMGVQRCLYKHYIVKRITSFGYDYLDNIRDDTVWNKTKKQLGNFASSA
                     SLKVIGSVASSVILKMIGV"
     gene            1940..2128
                     /locus_tag="KRH82_001549"
     CDS             1940..2128
                     /locus_tag="KRH82_001549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654832.1"
                     /translation="MNKIATKSRAEYMKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNL
                     TKKEWLEEKIDEELEQKE"
     gene            2249..3115
                     /locus_tag="KRH82_001550"
     CDS             2249..3115
                     /locus_tag="KRH82_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
                     /protein_id="HBG8654833.1"
                     /translation="MKNLIVKEFNGSQIYTFMWKEKSCWIANQIVGLFDYADVSKTIQ
                     DCIKAEDFEIEQEYDVLKGNEFNDFVTTLNVVANNIISNKARSITIFYEDGLYGFLQY
                     TDKPIGVQFRKWLRREVLPAIRQHGAYITNNADPQALREKANEIESLDTVNKTIEILT
                     PFLDNAGIDEKAKLLTAKTIYKKAGIELPLEIEEKEHFFDTVQIATKLNVYSKSNKPA
                     FHAIGEIIKKLDIQDNEKLVVLESKRGWSGSVNKYSQSVIDKIRHWIEENNRPTKIQG
                     EKKNFHVVYKIE"
     gene            3170..3325
                     /locus_tag="KRH82_001551"
     CDS             3170..3325
                     /locus_tag="KRH82_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654834.1"
                     /translation="MCENLLDMDRIELIRELGSIFEKMRNENPDKFYRFVSLVKEECR
                     KKEEKNK"
     repeat_region   3423..3782
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3490..3518
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            3916..4440
                     /locus_tag="KRH82_001552"
     CDS             3916..4440
                     /locus_tag="KRH82_001552"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654835.1"
                     /translation="MWGKFKKLSLLKKILVIFLIYFVVFTVSMMIHQAIRDSKNRDEV
                     NEGNITKENIISEREKEDIYKQEMQAKVDSMIPEDLKDKTTYYVNILNPTKGEGYIVS
                     IQVENSRFNDENECRNFTKEFVNNIKDMNDIHSVRISFIVDVTLTYNVFLDDWNNIKN
                     NVNLIDDLDFSSGN"
     gene            4618..4806
                     /locus_tag="KRH82_001553"
     CDS             4618..4806
                     /locus_tag="KRH82_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654836.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            4924..5745
                     /locus_tag="KRH82_001554"
     CDS             4924..5745
                     /locus_tag="KRH82_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBG8654837.1"
                     /translation="MKNELMMFEEKKVEVLEYNGQVLFNPYDCGRCLELSDSAIRNHL
                     SKMNDTQAVLLKNSNVLDKDFRKLHNTGEKFLTESGVYKLIFKSKKEEAERFQDWISD
                     EVLPAIRQTGAYITNNADPDKLREKASEIEKLQLAYNSTSMLKELLDGAGFDNKSKLL
                     TAKTLYKKAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQMAVCEIIKKIDLEE
                     NEVKGVWETNGSWTGTVNKYTKSVIDKVRNWIEENNRPAKIAGEKKNYHVVYKIE"
     gene            5808..5984
                     /locus_tag="KRH82_001555"
     CDS             5808..5984
                     /locus_tag="KRH82_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654838.1"
                     /translation="MCENLLNEYNLKTDEDVEYFVKFATLLYKLKQDNEEKFQEYAEI
                     LRGILREQQERENK"
     gene            6350..7123
                     /locus_tag="KRH82_001556"
     CDS             6350..7123
                     /locus_tag="KRH82_001556"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBG8654839.1"
                     /translation="MGLFSGNESCCICGEKGKQKISDGVICSECLKKYKDTFSIVEPT
                     DVIKKISSEEIKKSIRLTLENKKRFESFNASKKVGIYLLVDENKKQLIISDKISNLNK
                     NKRVYDFRDIISFELLEDDESIIKSGLGGAIGGGLLFGETGAIAGSILGKKKIKTYVN
                     SLKIKITINNIKNSTKYIYLINSKISTNSSLYKESYNYAQEILSTLSIITSSKSIEDK
                     KESISSSTADEILKYKNLLNMEAITQEEFDAKKKELLNL"
     gene            7190..9478
                     /locus_tag="KRH82_001557"
     CDS             7190..9478
                     /locus_tag="KRH82_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBG8654840.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMTNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIREADEQQKRFNDDVRKGASSTDKLVENAKRLVA
                     TYIGLRSVGGLINLSDQMTSTNARLAMINDGQQSDGGLNKMIFQSAERARASYLDTAK
                     IVSRVGMNAGKAFSSTKEIVAFAEQLNKKFVIAGATTEETNSVLLQLTQGLGSGVLRG
                     EELNAVFESAPNIIQSIADYLEVDIGKIRGMASEGMLTADIVKNSLLSAAEQTNAEFE
                     KMPYTFGQIWTSIKNNAVMIFGVIQKKIEQSMSSRGFRTFIDNFISGLYVLGNVFFNI
                     FNGIISILGSPAFQSFSNTMIVGISLISQALGWIVTQALNLANIFAQNWSIIGPIIAG
                     VVGILGTYLIALGSIWLWETLCKISKNALAIASAIHALAIHAELTETQMATVAQWGLN
                     AAILACPIFWIVAGIIALVAVLFVGVAIFNHFAGTSVSAIGIVAGAISVAAAFVGNLF
                     IATGNLIIDIVALIYNSLANFAEFFANFLDDPIGSVIRAVSRMADAVLGILRSIASAI
                     DTIFGSNLANAVSGWQDKLQGWTDKVAGEAKIKVELMDPNKLHFDRFNCGKAWDAGYK
                     WGDKLETNIKDKFDISKIAEKAKKDLGLDDLWDDKYGLGDGFGSAGLNSPLNDAAKGA
                     KDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVNIKIDMNNTNNISKDTDVD
                     GIVNVLTEKLNDAMIVSAEGIV"
     gene            9494..10183
                     /locus_tag="KRH82_001558"
     CDS             9494..10183
                     /locus_tag="KRH82_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBG8654841.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKNLSKY
                     TIYKGQVLKLG"
     gene            10176..12068
                     /locus_tag="KRH82_001559"
     CDS             10176..12068
                     /locus_tag="KRH82_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8654842.1"
                     /translation="MVDELVLANDRDVRLVIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYNNQTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSTTKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDILLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            12082..12342
                     /locus_tag="KRH82_001560"
     CDS             12082..12342
                     /locus_tag="KRH82_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBG8654843.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            12347..12766
                     /locus_tag="KRH82_001561"
     CDS             12347..12766
                     /locus_tag="KRH82_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBG8654844.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFQNVKGKVHCKFTVYSKYGDIKAEKVVSV"
     gene            12767..13816
                     /locus_tag="KRH82_001562"
     CDS             12767..13816
                     /locus_tag="KRH82_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBG8654845.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAVELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPIDSRFNLGE
                     YNYVAIERISEKTYKMKCETAGPIFELGQLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKV
                     PSSDLVNLVQEEIDPLQNQGEGLGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINEVKSNL
                     TINSNSIVVRCEVVG"
     gene            13809..14426
                     /locus_tag="KRH82_001563"
     CDS             13809..14426
                     /locus_tag="KRH82_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBG8654846.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSN
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            14438..15214
                     /locus_tag="KRH82_001564"
     CDS             14438..15214
                     /locus_tag="KRH82_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBG8654847.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASITGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELNSKVGDTTLLTTTDKTNIVNALNEVKKTSVDSIETTAEKTSYN
                     NATSKLNATNVQGAIDEIVAEVRGNRSSIISSINDNLIPM"
     gene            15230..16327
                     /locus_tag="KRH82_001565"
                     /pseudo
     CDS             15230..16327
                     /locus_tag="KRH82_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903579.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16706..17053
                     /locus_tag="KRH82_001566"
     CDS             16706..17053
                     /locus_tag="KRH82_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654848.1"
                     /translation="MNRGNRIIYNQDGKILLQTGEATGDILEHDTITELNFIDLEFGS
                     IDYSKQYIESINPVTKEPVLKNIEIVLTNEQKRLEVLEKELSMLKEENKNRDSEIVNT
                     AFEIENIKLNNNI"
     gene            17065..17235
                     /locus_tag="KRH82_001567"
     CDS             17065..17235
                     /locus_tag="KRH82_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654849.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTSL
                     LKKEEIPAEPTV"
     gene            17371..19146
                     /locus_tag="KRH82_001568"
     CDS             17371..19146
                     /locus_tag="KRH82_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654850.1"
                     /translation="MATVYEFNYTGSEQRATLKPGKYKLECWGACGGRYKADDFTTCA
                     KGGYAKGEIILKEKTNFRICVGQSGYEKVLSTSSFTRTGYNGGGAGGYSNFAPYKWSF
                     DGGGSTDIRLSSGNSSWDDLEGLLSRILIAGGGGGASESSVSKLGHGGGLNGDNGIGY
                     QGNFAGGGTQYQGGINNSSDFDGLFGKGGSYNKHIGGGGGWFGGAGCVTTQSAAGGGS
                     GYALTKDSYKPQGYIPSSEYWLENVVMTAGGNTTKADGYAKITLLQALPFLNISSYNS
                     TQAIFKADHTDPTLLTKIEYFIDDTLKETITTDLTTEKTINYTLEDNALHTLKIVVTD
                     NANATAEKVVSISKNIMPLEDGASLQDIATKVSEMKDGLKSGKRSIVNVLTLKDIDAS
                     LNNTFVELSEKVKDYFDNADYFFQEANKGKELIATTIGSPATKENTYQELSSYITEFK
                     NTIGTLTTQLESANNKLTDPYITKVNNRGVPSTFTVDFRMYYPSSSFTRRSTCIYVDA
                     TFIHYTTPGDMSTGVHKSVKYVKTDTKDLNGYRIFYDGDGTLSLTYENNSVRVVIQGG
                     YTSSPGRKKSDVYSYNVRMVNTYWD"
     gene            19250..19540
                     /locus_tag="KRH82_001569"
     CDS             19250..19540
                     /locus_tag="KRH82_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654851.1"
                     /translation="MEEISINLLCAVAGVIISYLAFRNSSNRKIQDETETTTKLEQQT
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            19544..19801
                     /locus_tag="KRH82_001570"
     CDS             19544..19801
                     /locus_tag="KRH82_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBG8654852.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPIILLVL
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKEENK"
     gene            19801..20607
                     /locus_tag="KRH82_001571"
     CDS             19801..20607
                     /locus_tag="KRH82_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8654853.1"
                     /translation="MKVVVVPGHTLTGKGTGAVGYIDEGKENRILTDLIVKWLKQGGA
                     IVYTGKVDKSNNYLAEQCEIANRQNVDLAVQIHFNANKTTLNPMGTETIYKTNNGKVY
                     AERVNKKLSTIFKNRGAKSDARGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKTIDNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTQNLYVVGGGACEKIGSITKEHYTMIKGNDRFDTLYKALDFIDR"
     gene            20860..22119
                     /locus_tag="KRH82_001572"
     CDS             20860..22119
                     /locus_tag="KRH82_001572"
                     /inference="COORDINATES: protein motif:HMM:NF014516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8654854.1"
                     /translation="MRKLDNIKKGTIILDIIPNSANGRDAMKIEKIEIKGIGGIKELS
                     LRFNKGLNIICGANGIGKTTILEVISHLFSIQSSDLKKNAKFDLGEAIADYSFEDIEA
                     VHKSTYQINDFNASVKELIFDNRDKKKYSKFVLFFKTHRELNYSKLDGITGDETYSDD
                     STSYMADLGIDSSKIKNWFINRLLFSKQEGSLTKEQLCNLDLAIEMISILDKNVSYSR
                     IVSDSLDLMINTPQGEIYIEYLSSGYKSCFYILLGIIKELEYRFTKPYIEVKDFDGVI
                     LIDELDLHLHPEWQVKIVNALKVLLPKAQIIATTHSPNMIQTLSPDEIIPLTMDENGN
                     VRKKDLELGEYGLQGWTIEEILTDVMGMKTTSSELYLDTMKKFDRAMDKENVDEIKKY
                     YDILMKMLHPNSTLRTILKIQVAGIID"
     gene            22116..22874
                     /locus_tag="KRH82_001573"
     CDS             22116..22874
                     /locus_tag="KRH82_001573"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654855.1"
                     /translation="MIKINRTRKPIELTEEVQKQLTEEFKNNKEKSVWRKKYITNALL
                     EMSHGKCCYCEMKLIEEGKSLNVEHFHHKDKYPDEVVKWENLLPSCGRCNSEKGTHDT
                     KLEPIINPAINNPKDYLYLYNYRYKSKNRNKLGSDTIDILYLNDTDKLIKPRVNICMA
                     LFKRLESIKTFVEDYQNGTGTHTRRKNKIINEVKGVLRCAQPTEEYSAIVANVIVNDD
                     DYKYIKEIMSEFNLWDNELEELESKAKEIMLDSE"
     gene            complement(22947..23435)
                     /locus_tag="KRH82_001574"
     CDS             complement(22947..23435)
                     /locus_tag="KRH82_001574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654856.1"
                     /translation="MSLKYWFKNIKKKKQIKKDIKYFKGNKESVINYQEYYTKIYNHY
                     NEIKNINTIRKIEIEQTRIKGQLEKNNNPGNALFFSLMAVVFSLLANLFLSSLNIKDN
                     YINLILQSSSIIVLIFIAINTSLDIAVPYRDEIQFYTTALDVLEDMKKKKLKERKYKK
                     RR"
     gene            complement(23770..24153)
                     /locus_tag="KRH82_001575"
     CDS             complement(23770..24153)
                     /locus_tag="KRH82_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654857.1"
                     /translation="MRKKLFLGIFIVLVIAAIVVLNIKNDKNIFIGESEHWTAKFVTT
                     EEQSELEIKYKDSKDVVKQKFNYSYEFIDGEDAIIILKDAVLESGQEKIIKRQRPGLY
                     SNRESNYKVIISWNKNEETINLKKK"
     gene            24300..24629
                     /locus_tag="KRH82_001576"
                     /pseudo
     CDS             24300..24629
                     /locus_tag="KRH82_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            24828..25043
                     /locus_tag="KRH82_001577"
     CDS             24828..25043
                     /locus_tag="KRH82_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654858.1"
                     /translation="MYINQTGFVSNGLGIKQQQRKDPTSNSFSYNAPSSWKPVGRDSL
                     QYNCGFESIATLVRGGSSWSFNFIVQP"
     gene            25390..26556
                     /locus_tag="KRH82_001578"
     CDS             25390..26556
                     /locus_tag="KRH82_001578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654859.1"
                     /translation="MLLGDEIKLNLEPSDLINSIPYFKSEYSDLCGLDADFIKEQLLK
                     AENNDRIVSMARGEGRAFVVEPIIKRNNYCKFRNNSYDIFNSIPSYEYAIKIIERYKN
                     HIFNPTEYRNSVMRRVGTYENDIFNWGYKSMHSYMESLPLREFLEPNKVDRTLLFEFL
                     DFMRELFSYQLRTYPGRFDNSKTLDAIETIKNAIIKTESHDDLLIIKEWLCFLLHTGN
                     HRVFKNITPWISLSTGSKRYNIVHKFASRKPFTSYRTISEKHTYNEKEKFIFIDYWEY
                     VDKENLTFRNTNYIVNKLKSMGVNWYENRNNEVMVKYALFPQQIIGYYYFENRKLQYY
                     FINPHYLKAWQKNKDFKIGDELYINQEQVVFPFNNPYRVIYGKKYGHISVVDKR"
     gene            26775..27164
                     /locus_tag="KRH82_001579"
     CDS             26775..27164
                     /locus_tag="KRH82_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8654860.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEVMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            27487..27996
                     /gene="vanZ1"
                     /locus_tag="KRH82_001580"
     CDS             27487..27996
                     /gene="vanZ1"
                     /locus_tag="KRH82_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBG8654861.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVAIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(28098..28292)
                     /locus_tag="KRH82_001581"
     CDS             complement(28098..28292)
                     /locus_tag="KRH82_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBG8654862.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(28808..29200)
                     /locus_tag="KRH82_001582"
     CDS             complement(28808..29200)
                     /locus_tag="KRH82_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8654863.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            29767..30129
                     /locus_tag="KRH82_001583"
     CDS             29767..30129
                     /locus_tag="KRH82_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654864.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSRIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            30113..30829
                     /locus_tag="KRH82_001584"
     CDS             30113..30829
                     /locus_tag="KRH82_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654865.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYLLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEYEEELKQNIIE
                     NIKKNFDEKNLVQVYKYRGV"
     gene            30849..31268
                     /locus_tag="KRH82_001585"
     CDS             30849..31268
                     /locus_tag="KRH82_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654866.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            31258..31782
                     /locus_tag="KRH82_001586"
     CDS             31258..31782
                     /locus_tag="KRH82_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654867.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIIGNSMGIMNISNYEETFKKTTSIKCRYVDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            32094..32651
                     /gene="efp"
                     /locus_tag="KRH82_001587"
     CDS             32094..32651
                     /gene="efp"
                     /locus_tag="KRH82_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBG8654868.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            32743..33198
                     /locus_tag="KRH82_001588"
     CDS             32743..33198
                     /locus_tag="KRH82_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBG8654869.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            33361..34071
                     /locus_tag="KRH82_001589"
     CDS             33361..34071
                     /locus_tag="KRH82_001589"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBG8654870.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            34125..35195
                     /locus_tag="KRH82_001590"
     CDS             34125..35195
                     /locus_tag="KRH82_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8654871.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     IFQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            35223..38777
                     /gene="smc"
                     /locus_tag="KRH82_001591"
     CDS             35223..38777
                     /gene="smc"
                     /locus_tag="KRH82_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBG8654872.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRNVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            38804..40084
                     /gene="ftsY"
                     /locus_tag="KRH82_001592"
     CDS             38804..40084
                     /gene="ftsY"
                     /locus_tag="KRH82_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBG8654873.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     FEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEIV
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            40187..40555
                     /locus_tag="KRH82_001593"
     CDS             40187..40555
                     /locus_tag="KRH82_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBG8654874.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNKD
                     CANLIPKLENIEDVCREMIK"
     gene            40552..41904
                     /gene="ffh"
                     /locus_tag="KRH82_001594"
     CDS             40552..41904
                     /gene="ffh"
                     /locus_tag="KRH82_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBG8654875.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            41942..42214
                     /gene="rpsP"
                     /locus_tag="KRH82_001595"
     CDS             41942..42214
                     /gene="rpsP"
                     /locus_tag="KRH82_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBG8654876.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            42279..42506
                     /locus_tag="KRH82_001596"
     CDS             42279..42506
                     /locus_tag="KRH82_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBG8654877.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            42614..43129
                     /gene="rimM"
                     /locus_tag="KRH82_001597"
     CDS             42614..43129
                     /gene="rimM"
                     /locus_tag="KRH82_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBG8654878.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            43138..43833
                     /gene="trmD"
                     /locus_tag="KRH82_001598"
     CDS             43138..43833
                     /gene="trmD"
                     /locus_tag="KRH82_001598"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBG8654879.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            44018..44368
                     /gene="rplS"
                     /locus_tag="KRH82_001599"
     CDS             44018..44368
                     /gene="rplS"
                     /locus_tag="KRH82_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBG8654880.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            44689..45585
                     /gene="ylqF"
                     /locus_tag="KRH82_001600"
     CDS             44689..45585
                     /gene="ylqF"
                     /locus_tag="KRH82_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBG8654881.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            45974..47266
                     /gene="brnQ"
                     /locus_tag="KRH82_001601"
     CDS             45974..47266
                     /gene="brnQ"
                     /locus_tag="KRH82_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBG8654882.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT        19398 a         4876 c         8443 g        14625 t
ORIGIN      
        1 caaaagatta tcctcccaac gtatagaagg gaggtgaata tgtatggata attttttgat
       61 tggtgtatta gctagtttaa cagctagtct aatcggttac atagtttgtc tatgtatcaa
      121 aaaagtaaaa agccactctg tgcaagagag tgacttagat gttgagctta aattttcatt
      181 taagttcaaa aaaaataagc attaaattgt ttagaacttc actctacttc caaatagatt
      241 gtagttcttc ttgtttttat tataccacaa attggtacag atattcaaaa ataatatatt
      301 tatgatataa taaaaatgta gagattttgc agtgttcgat ttttgtaata aaatatggtt
      361 taacaattgg aatacaaggc attgagggtg tgtgataaat gttatcaatt gcactactca
      421 tggttcactg caaatttgag agaggtgtgt atgtgtaggt attggaaatg ctaagtttat
      481 tttggggttt tagattaact atatggaatg taaataattt ttcgagagtc tcaatttaca
      541 gaagaaattg gagttttaga ttaactatat ggaatgtaaa tcaaattgtc taatcctaat
      601 tttttctttg catcttctgt tttagattaa ctatatggaa tgtaaattgt aattaagtta
      661 gatatggcaa aagaaatagc tatgagtttt agattaacta tatggaatgt aaattttaat
      721 gattctacaa ctcttacaga ctcagatgat gttttagatt aactatatgg aatgtaaatg
      781 ggtgggagat atggcaacta tccacacatg aaattggttt tagattaact atgtggattc
      841 aaaattaaat aaacaaagaa agcacttaca aacatgtagg tgcttttgtt atgtaaaaaa
      901 atagaggtga ttaaatgaat aaagatatag aatttattgc ctgttcaatg aggttaaaaa
      961 ttttgataca agcaagagaa gacttaattg aaaatataaa taaatattca actaagtctt
     1021 atgaaaaaaa tattgataat tataaaaaat tagatatgat tttcgaagat gctataaagt
     1081 ttgaagctat actcctatca tctttaaaat aacactagat gcaacactgc ctataacttt
     1141 taaagaggcg gaagatgcaa aattacctaa ttgtttttta gttttattcc aaacagtgtc
     1201 atctcttata ttgtcaagat aatcataacc aaaggaggtt atcctcttaa caatataatg
     1261 tttatataag catctttgaa cacccattgg tgtagcttca ataaagccaa catccaataa
     1321 taattgtaaa tgataagaaa tagttctttc atcatagaca tcagtcatga aatcactgat
     1381 agacattcta tcagcatcag attcttccat tttgattaga atatctctta tcaattctaa
     1441 atcacgtttc attatatcac catcctttca taattaattt aggaagtatc tactaatatt
     1501 tcctaaatta attatagcat ggtatattag ggagatttgt ttatattaag aataatatgt
     1561 ggatatttta tgtatgtagt atatgaacta aatagataat atagtaagca cttacaaata
     1621 tgtaggtgct tttataaaat atttgaaatg atagcacatt cccgttttgg gaacatggtc
     1681 aaaactcaaa ctatattact agtatattaa atatgtagta tcaaaattaa ataaagaaaa
     1741 ggaagcactt acttttggta ggtgcttttg ttttgctcaa atttggtcgg ttgggtaaaa
     1801 taattagaaa aaaagatata gctgaggtag tgttttacga cgctagcttc aataaaattt
     1861 tatttgcaaa atattccaaa atagcttgac tgtaactcgt tacaatgtta ttattaatgt
     1921 aacgagttac agaaaagagg tgaataaaat agcaactaaa agtagagcag agtatatgaa
     1981 aaatcgtcga aaagataaaa gaggttttag tgtactttta gacaaagaaa agttagataa
     2041 atttgatgaa gtgttagaag agaagaatct aactaagaaa gaatggctag aagaaaaaat
     2101 cgacgaggaa ctggaacaaa aggaataaaa aataagggtc actcccaccg accaaagttt
     2161 gagcaaccct tattgacgta tactatacat caactaacta tagtatacgt cattccttaa
     2221 aaaatttcaa ttaaggagtg taatagttat gaaaaattta atagtaaaag agttcaatgg
     2281 aagtcaaatt tatactttta tgtggaaaga aaaatcttgt tggatagcta atcaaatagt
     2341 tggattattc gattatgctg atgtatctaa aacaatacag gattgcataa aagcagaaga
     2401 ctttgagatt gaacaagagt atgatgtatt gaaaggaaat gaatttaatg attttgtaac
     2461 tactttaaat gtagtcgcaa ataatataat tagtaataaa gctagaagta taactatttt
     2521 ttatgaagat ggtttatatg gatttttaca atacacagac aaacctattg gtgtacagtt
     2581 taggaaatgg cttagacgag aagttttacc agctattcga caacatggtg catacataac
     2641 aaataacgct gaccctcaag cattaagaga aaaagcaaat gaaatagaaa gtttagatac
     2701 agttaataag actatagaaa tactaactcc attcttagat aatgctggaa tagatgaaaa
     2761 agcaaaatta cttacagcaa agactatcta caaaaaggca ggaatagagt tacctcttga
     2821 aatagaagag aaggaacatt tctttgatac tgtacaaata gcaactaagt taaatgttta
     2881 ttctaagtct aataaacctg catttcatgc aataggtgaa attattaaga agttagatat
     2941 acaagataat gaaaagttag tagtactaga gagtaaaaga ggttggagtg gaagtgtcaa
     3001 taagtattca cagagtgtaa tagataaaat aagacattgg atagaggaga ataatagacc
     3061 tactaagata caaggtgaga agaagaattt tcatgtggtt tataaaattg agtaaattta
     3121 tcagttgtat taaataatat attttagttt attttggggg gttaatacaa tgtgtgagaa
     3181 tttacttgat atggatagaa tagaacttat tagagaactt ggaagtatct ttgaaaaaat
     3241 gagaaatgaa aatccagata aattttatag atttgtaagt ttagtgaaag aagaatgtag
     3301 gaaaaaagaa gagaaaaata agtaaataat ataaataaag cacttggata ttatgttgtt
     3361 tcaagtgctt tgtttgttaa aaagtggtat aataaaaata tagaaatcta taaacacaag
     3421 tcgttttata ttaactaagt ggtatgtaaa tcgtacagat agtattgcat tagaggaaag
     3481 tttaaaagcg ttttagatta actatatgga atgtaaatgt ttttaaagct tcttcaagtt
     3541 gtatttgtgt ataatgtttt agattaacta tatggaatgt aaatccaact gaataaacaa
     3601 taattttatc aatttcttta gttttagatt aactatatgg aatgtaaatt attttacaga
     3661 tgaacaatta caattacttc ttgaatgttt tatattaact aagtggtatg taaataaagc
     3721 aaaagatagg aatgataatt ttaaaactcc aaacttttat attaacaatg tggagaaaaa
     3781 ctaaatagaa gaaagaagca cttatttttg gtaggtgctt ttattttgct caaaatattt
     3841 taaatcaata gactaagttc ttatttttag atagaattat atttgaataa agaatttaat
     3901 aggggagagt tcattatgtg gggaaaattt aaaaaattaa gtttgttgaa gaaaatttta
     3961 gtgatatttt taatatactt tgttgtattt acagtatcaa tgatgattca tcaagcgata
     4021 cgagattcaa aaaatagaga tgaagtaaat gaaggaaata ttacaaaaga aaatataatt
     4081 agcgaaagag aaaaagaaga tatttataaa caagagatgc aagcaaaagt agactctatg
     4141 ataccagaag acttaaaaga taaaacaaca tattatgtta acatattaaa cccaacaaaa
     4201 ggtgagggat atatagttag tattcaagtg gaaaattcta ggtttaatga tgaaaatgag
     4261 tgtagaaact ttactaaaga atttgtaaac aatataaaag atatgaatga tatccattca
     4321 gtgagaataa gctttattgt tgatgtgaca ctcacttata atgtattttt agatgattgg
     4381 aataatataa aaaataatgt aaatttaatt gatgatttgg atttctcgtc tggaaattag
     4441 gtgaatactt tattttaaaa ttaaatctgt tatatagaaa gcacttactt tttggtaggt
     4501 gcttttgttt tgctcaaaat tggtcggttg agtaaaataa ttagaaaaaa ttagtaaaaa
     4561 ctcttgaaaa gtgtcgcgat acaatgtata attatattat cgcgatacag aaaagaggtg
     4621 aaaattatta ctgatagcag tagagcagat tacttcaagc agagacgaca gaataagaaa
     4681 acttttagtg ttctactaga tagagagaaa gtagaaaaaa ttgaagaaca tttaaaaaag
     4741 cagaacaaga ctaaaactat ttggcttgaa gaaaagatta atgaagagtt agaaaaagag
     4801 gaataaaaaa taagagacgt tctccccgac caaagattga acatccctta ttgacgtata
     4861 ttatatacac taactatagt atacgtcatt ccttaaaaaa attcaattaa ggagtgtaat
     4921 attatgaaaa atgaattaat gatgtttgaa gaaaagaaag ttgaagtact tgaatataat
     4981 gggcaagttt tatttaatcc atatgattgt ggaagatgtt tagagttaag tgatagtgca
     5041 ataagaaatc atttatctaa aatgaatgat actcaagctg tattattaaa aaattctaat
     5101 gtcctagata aggactttag aaaattgcat aacacaggtg aaaagttctt aacagagagt
     5161 ggagtatata agttaatatt taaatctaaa aaagaagaag ctgagagatt tcaagattgg
     5221 ataagtgatg aagtacttcc agccattcga caaactggtg catacataac aaataatgct
     5281 gacccagata agttgagaga aaaagcaagc gagattgaaa aattacagtt agcttacaat
     5341 agtacatcta tgttaaaaga actattagat ggtgcaggct ttgacaataa atccaaacta
     5401 ttaacagcta aaacattata taagaaagca ggaattgatt taccaataga gataaacgaa
     5461 gaagaacatt attttgatac aaagcaaata gcatctaaac tgaaaatata ttctaagagt
     5521 aataaaccag ctcagatggc tgtttgtgaa attattaaaa agattgattt agaagaaaac
     5581 gaagtcaaag gcgtttggga aactaatggt tcttggactg gtactgtaaa taaatataca
     5641 aagagtgtaa tagataaggt tagaaattgg atagaggaaa ataatagacc tgctaagatt
     5701 gcaggtgaaa agaagaatta tcatgtggtt tataagattg agtaaattta tcagttgtat
     5761 taaataattt agtttagttt attttagttt tgagggggat taatacaatg tgtgagaatt
     5821 tacttaatga atataattta aaaactgatg aagatgtaga atactttgta aagtttgcta
     5881 cattattata taaattaaaa caggacaatg aagaaaaatt tcaagagtat gcagagatat
     5941 tgagaggtat tcttagggaa caacaagaga gagaaaataa gtaaaataat atggataaag
     6001 cacttggata ttatgttgtt tcaagtgctt tatttggtaa aaaatggtat aatataggta
     6061 ggaaattata ttaactaagt ggtatgtaaa gggagtaggc aagttttata aacaaataac
     6121 aggaagattt tatattaact atgtggtatg taaatgcgtt taggaatatg acagcatcta
     6181 ttaatacgac aagttttata ttaactatgt ggacttaaaa ttaaaaataa ttcaaaaaca
     6241 cttacaaatg agtaagtgtt tttttaatga aaggaggtga taatgatgta aaaattttac
     6301 tgatatagta taataatcct ataaattcat tataataaag ggggatatta tgggattatt
     6361 tagtggaaat gaaagttgtt gtatatgtgg agaaaaaggt aaacaaaaaa tatctgatgg
     6421 tgtaatatgt tctgaatgtt taaaaaaata taaagataca ttttctatag tcgaaccaac
     6481 agatgtaatt aaaaaaatat cttctgagga aataaaaaaa tcaataagat taacacttga
     6541 aaataaaaaa agatttgaat cttttaacgc aagtaaaaaa gtaggaattt atttattagt
     6601 agatgaaaat aaaaaacaat taattatatc tgataaaata agcaatttaa ataagaataa
     6661 gagagtatat gactttaggg atattatttc atttgaactt ttagaagatg atgaatctat
     6721 aattaaaagt ggattaggtg gtgctattgg aggaggtctt ttatttggcg aaacaggagc
     6781 tatagctgga agtatattag gaaagaaaaa aataaaaact tatgtaaata gtttaaagat
     6841 aaaaattaca attaataata taaagaattc tacaaagtat atatatttaa ttaattctaa
     6901 aatttctaca aattcaagtt tatataaaga atcttataat tatgcccaag agattttatc
     6961 aactttgtct ataataacaa gttctaagag tatagaagat aaaaaagagt ctatatctag
     7021 ttctacagct gatgaaatat taaaatataa gaatttgtta aatatggaag ctattacaca
     7081 agaagaattt gatgctaaga aaaaagaatt gctaaattta taatatataa gcacttactt
     7141 aaaaataagt aagtgcttat attatgttaa aaaagaaagg aggttaaaaa tggcaactat
     7201 acaaacatct atccgaattt tcgacggaat gacacctgct tttagacaca tgactaatgc
     7261 tatgaatatt gtattaagtt cattcgagca attacaaaga acatctagca atgctataga
     7321 tgctaatagt attagaacag ctagagaaga actagcacgt gcagaagctg ggtttgatag
     7381 attagaacaa caaataagag aagctgatga acaacaaaaa agatttaatg atgatgttag
     7441 aaaaggagca agtagtacag ataagttagt agaaaatgct aaaagattag tagcaactta
     7501 tattggattg agaagtgttg gtggtttgat taatttaagt gaccaaatga cgagtactaa
     7561 tgcgagacta gctatgataa atgacgggca acaatctgat ggaggactca acaaaatgat
     7621 atttcaatca gcggaaagag caagagcatc ttatttagat actgcaaaaa ttgtaagcag
     7681 agtgggcatg aatgcaggca aagcatttag tagtacaaaa gaaatagtag cattcgcgga
     7741 acaacttaac aagaaatttg taattgcagg agcaacaaca gaagaaacta attcagtact
     7801 tttacaactt acacaaggtt taggaagtgg cgtgttaaga ggcgaggaac taaatgctgt
     7861 gtttgagtca gcacctaata ttattcagtc tattgccgat tatctcgagg tcgatatagg
     7921 gaagataaga ggtatggcaa gtgaaggaat gttaacagca gatattgtaa aaaactcctt
     7981 actttcagcg gcggagcaga ctaatgcaga gttcgagaag atgccttata catttggaca
     8041 gatttggaca tcaataaaaa ataatgcagt catgattttt ggtgttatac agaaaaaaat
     8101 agaacaatct atgtctagcc gaggtttccg aacctttata gataatttta tcagcggatt
     8161 atatgtttta ggtaatgtat tttttaacat ttttaatgga attataagta tattagggag
     8221 cccagctttt caaagttttt caaacacaat gattgttggg ataagtttaa tttcacaagc
     8281 actaggctgg atagtaacac aagcattaaa ccttgctaat atatttgcac aaaattggag
     8341 tataataggt ccaattatag caggggttgt agggatttta ggtacttatt tgattgcatt
     8401 aggaagtata tggctttggg aaactttatg caaaatatca aaaaatgcct tagcaattgc
     8461 ttctgcaata catgctttag caatacatgc agaattaaca gaaactcaaa tggctacagt
     8521 tgctcaatgg ggtttaaatg cagctatttt ggcgtgtccg attttttgga tagttgcagg
     8581 aataatagct ttagtagcag tcttatttgt aggagtagca atattcaatc attttgcagg
     8641 gactagtgta tctgctatag gtatagttgc aggtgcaata tcagttgcag ctgcttttgt
     8701 aggaaattta tttattgcaa cagggaactt aattatagat attgtagctt taatttataa
     8761 tagtttagca aactttgcag agttctttgc taacttttta gacgacccga tcggctctgt
     8821 cataagggcg gtatctagaa tggctgatgc ggtattaggt atattaagaa gcatagcatc
     8881 tgcaatagat accatatttg gctcaaatct agcaaatgca gtgagtggtt ggcaagataa
     8941 attacaaggg tggactgaca aagtagcagg agaagctaag ataaaagttg aactaatgga
     9001 ccctaataaa ctgcattttg acagatttaa ttgtggaaaa gcttgggatg caggatataa
     9061 atggggagat aaattagaaa ctaatataaa agataaattc gatattagca aaatagcaga
     9121 aaaggcaaaa aaagatttag gtctagatga cctttgggat gacaaatatg gattaggaga
     9181 tggatttggt tcagcaggtc ttaattcacc tttaaatgac gcagcaaaag gagcaaaaga
     9241 tacagcagga aatacagcta aaatggctaa aacaatggat aaaagtcaag aagacttaaa
     9301 atatcttaga gatattgcag aacaggaaac aataaaccga tttacagggg taaacataaa
     9361 aattgatatg aacaatacaa ataacataag taaagataca gatgttgatg gaatagttaa
     9421 tgtcttaact gaaaaactga atgatgctat gattgtatca gcagaaggaa tagtttagaa
     9481 aggagggata taaatggctt atgactttta tttagatgga gtacaattac caatacctcc
     9541 gccaaagtta gagattaaag ttacaaataa aaacaagaca gttgatttga taaatactgg
     9601 agaagtaaac atactaaaaa aagaaggatt atctgaaata agttttgaag cagaatttac
     9661 acataataag ttgccattct atcgtggagc ttttagggat gttcaattct ttttaagtaa
     9721 actggaacta ttaaaaactg attgtaagcc atttcaattt attgtatcga gggaattagg
     9781 taataaagta ctatttaaca ctaatataaa agtatctctt gaagagtatg ctatttcaga
     9841 agatgcagaa aatggctcag atacaaaagt tgcaataaag ttaaagcaat atagagatta
     9901 ctcaactaaa aagttagttc ttgcccctcc taaaaatgag actggtagac ctaatgtaaa
     9961 gatagagcca aaacgagttg attcagtcaa tgccacaaac actaaaacat atacagtaaa
    10021 agcaggggat agcctttggt caatttgtca gaaacaactt ggtaatggtt cattatataa
    10081 gaaagtatac gaattaaata aatctatgat ggataaggca aataagggga agaatttaag
    10141 taaatacacc atttataaag ggcaggtgtt aaaacttggt tgatgaatta gtgttagcaa
    10201 atgatagaga tgtaagatta gtaatagctc attgggaaga tttctacgaa cctgctgtca
    10261 ttgatggtat cacatgggag atagaaagaa gaggaacacc ttctaagtta gaatttacaa
    10321 tagttatgga tgatatatta gagttttgcg aaggaaattc tgtaaggctg tattataaag
    10381 gaataggtat cttctatgga tatatatttc agaagaaaag agataaagaa aatcacataa
    10441 aaattgttgc ttacgaccag ttgagatatt ttaagaataa agatacttat gtatataata
    10501 atcaaactgc atctgaactt gtaaagatgt tagctaaaga ttttaattta aaatacaatg
    10561 tcatagaaga tactaagtat aaaatatcta ggatagaaga aaataaaaca ctctttgaca
    10621 tgatactaac agcactagat gatactctaa gagagaaaaa agaaatgtat gttttatatg
    10681 atgattttgg aagaataaca ttaaagaatg ttgcttctat gaaacttgat acggttatga
    10741 acaatgatgt aattgaggac tttgactaca attcttctat tgatagtgat acttacacaa
    10801 agattaaact tgtgagagat aatgaagaaa cagggaaaag agatgtatat attgcacaag
    10861 actctacaca tatgaggagt tggggaatac ttcaaatgtt tgatacagta gataaaaaca
    10921 tgagtgaagc agaaataaaa caaaagtgtg atatacttct aaaactatat aataagaaaa
    10981 ctaagtcatt aagtttaaaa aatgtacttg gagatattag agtaagagca ggttgtttag
    11041 tacctgtttt tttaaatcta ggagatatta aacttcaaaa ttatatgtta gttgagaaag
    11101 taaaacatac atttgaaaat aattcacatt tcatggattt gactcttgtt gatggagatg
    11161 aatttgcttc ttattcttca agctcatatt caagtggaaa tactaacaat aaggatgaaa
    11221 agaaaaatgg tcctgcacaa agtactacga aaaaaaatac aggtaaaaaa gttcctgcta
    11281 tatttactgc atattatcca gggaacaatg caatggaagg tggaaaaaca gattgcaatg
    11341 gaaagccact tgatgtaaaa tcaagaactg ttgctggtcc aatgaatcga gaaggagtta
    11401 agaaaacttg gtatactgat gattttctaa agaaacatcc agtttttgaa tatggagata
    11461 aagtaaaaat tatacttcct ggtactgcct atgacaacaa agtatataca gttaaagata
    11521 atggaggaag aatatatgtt gaaacaaacg gaacatatca tatagatata ctattagcta
    11581 atgctagtga atgtaaaaaa tttggtagaa agaatggcta tataattata ggtggagatg
    11641 aagaacaaac atatcaagtt gaaggtaata accaaagtag tacaaataat aactctaaag
    11701 aagataaatt aattagtata gcaaaaagta aactgggttg taattatgtg tatggagcag
    11761 aaggtcctaa taattttgat tgcagtgggt ttactcaatg gtgttataaa caaataggta
    11821 taaaaattcc tcgtactgct tctgcacaaa gtaaagcagg aaaagcagta gatttaaaag
    11881 atagaagcaa gtggaaagca ggagacttat tatgtagaat tggtggagga agtagtaatc
    11941 atgttgtaat gtacattgga aacaatcaaa taattcattc accacaaaca ggagatgtgg
    12001 taaaaataga gtctgttaat tcttatagaa aaggaaaagc atacacacat gtgagaagat
    12061 ttatataagt gaggtggcaa tatgagccaa gatttattac agataataaa aaaagctgca
    12121 atggatgcag tagaaacaag caacccaatg agggttgtat ttggaacaat agaaagtatt
    12181 agtcctctaa gagttaagat agaacaaaaa ctatctattg gtgaaatttt tctaatacaa
    12241 acagatacat ttaaaagata tacagataaa aaaataggag ataaattagt cttaattcgt
    12301 atgcaaggag gacaacaata cttgatttta gataggatgt gatgaagtgt taccaagcga
    12361 taatttagat tatgacattg aagatgtatc aataattaat tttgatgtaa ggcaagaacc
    12421 aagtaagacc tttaaattaa atatagaaaa atctaagata gatggtattt gtgatgatgt
    12481 tgaagcatta aaacaaacca tctttttaat tttaaacaca gagagatacc aacatctaat
    12541 atatagttgg aattatggag tcgagttgaa cgaccttatt ggagagccta tatcctttgt
    12601 aatccccgaa cttgaaagac gaatcaaaga agcactaatt caagatgata gggttgaaaa
    12661 tgtagataat tttgagtttc aaaatgtaaa gggtaaagta cattgtaagt tcacagttta
    12721 cagtaaatat ggagatataa aagcagagaa ggtggtgagt gtataattgt ttgagttaat
    12781 gacatttgaa aatataatta aaagaatgtt agatagtgta ccagatactt ttgataaaag
    12841 ggaaggttct ataatataca atgctcttgc tcctgttgca gtggagctta cagaaacata
    12901 cattgcaatg gatgaattac tagaccaaac attcgtagat actgctagtt attactattt
    12961 agagaagaga tgtaaagaga gaggtattac acctttacct gcaaccaata caattgcaaa
    13021 aggagttttt aatatagata ttcctattga ttcaagattc aacttaggag agtacaatta
    13081 tgtggcaatt gagagaatat ctgaaaaaac atataaaatg aaatgtgaaa ctgctggacc
    13141 tatatttgag ttagggcaat taatacctat cgaatatata gatggtcttg aaactgctga
    13201 gttaacagaa atactaataa atggagaaga tgaagaatca gaggacagtc taaggcaacg
    13261 atactatgat agtttaaact cacaaagttt cggtggtaat atacagaatt ataaggatga
    13321 agttaataaa ttgcctgacg ttgggggagt taaagtatat ccagtttgga acggtggagg
    13381 tactgttaag ttagtaataa ttaattctaa cttcaaagtt ccatctagtg atttagttaa
    13441 tttagttcaa gaagaaattg atcctctaca aaaccaagga gaaggtcttg gattagcacc
    13501 aattggacac cgagtcacag ttgaaggagt tacaagtaca actataaata tatcagcaga
    13561 gataacatac aaaaatggct acacttggga gaatataaaa tcaattgcag aagaagcaat
    13621 agacgactat ttaaatgaac ttaacatgag ttgggaagat gaagaaaact taatagtccg
    13681 tatatctcag atagaaactc gtttgttaag tatagatgga gtgttagata ttacaaacac
    13741 aatgataaat gaggttaaat ctaatctaac aataaatagt aacagtatag tagtgagatg
    13801 tgaggtagtt ggataaagag attaatctaa taaattactt accacaaatt ctgcaagata
    13861 aagaagaata tataaaagta tttaatgtag aaaataaaga aataaaaaca ctacatgaaa
    13921 aattaaatga cctatcaaat gaccagtttt tagaggattt aactccaagt ggcataaaaa
    13981 gatgggaaaa gataatgtct ataactccta aaagtaatga gagtttagaa gatagaaggt
    14041 ttaggatttt tagtaaatat ataagtaaat taccttactc agagagattt ttaaggaact
    14101 ggctagataa tgtagttgga gaaggcaatt atgaattaac tattaataat gctacttata
    14161 acatacacct tgagagtgat gctagaaatc aagattggtt tgaggaggtt cattcttttg
    14221 taagtagtat taaaccttgc aacatgactt tagattacac tagagtgctt gtaagtaaag
    14281 acaattatat gaattttggt ataacaaccc taataggtca agaaataact atataccctt
    14341 ggagtccacc agatatagaa acttatggag aaattgatgt attaactggc aatggagttg
    14401 gataccaaga gataacaata ttttaggagg tgatatattg gctatagata aaagttatta
    14461 cactataatt acagatgtag gaaaagcaaa gatagcaaat gcaagtatca caggtaataa
    14521 agtgggattt gtaaaaattc aacttggtga tggaggaggg agtgaatata ctccaactga
    14581 gagtcagaca gctctcaaaa atgtggtatg ggaaggcaat atcggaaata caaccacaga
    14641 tgaaactgca ccaaattgta taatattaga gagtttaata ccatcaagtg taggcgggtt
    14701 tatgataaga gaaataggat atttagatga tgaaaataat ttaattgcca tttctaaata
    14761 caaagagtgt tataaacctt ctatagaaca aggtgcagtg gtagacatga aggttaaaac
    14821 tgtgcttatt gtatctaatg taaataatat agaacttaaa attgacccaa caataatctt
    14881 tgcaacactc aaagatatac aggacttaga aactaaaata ggtactgtta atactaaaat
    14941 tgatacaact aaaacagagt taaacagcaa agtaggagac acaacactac ttactacaac
    15001 agataaaaca aatatagtta atgcattaaa tgaggtaaaa aaaactagtg tagatagtat
    15061 agaaacaaca gcagagaaaa caagttataa taatgcaaca agtaaactta atgctacaaa
    15121 tgttcaaggg gcgattgatg aaatagtagc agaggtaaga ggtaatagaa gtagtattat
    15181 atctagtata aatgataatt tgataccaat gtagaaagga tgtgattaaa tgcctccagc
    15241 ggagacgttc atatgtaata gaattgttaa aaaaagaaga ggttattatt cagaacgaga
    15301 tgtttttctt tcaccttgtc cttatgttta tggagaaggc ggtatgtatg agtcaactta
    15361 ctatggtgag tttgatttaa gtaattctaa atatataaca gttcctacaa gtaccaaata
    15421 tgaaaaaact gcaactcgtg tttattttat atctggtgga aatatgataa ctagtagtag
    15481 tggaatgaaa caagctatta ctcttgaact tataccagac cctaatatta ttataaatga
    15541 tgatttaggt gttattagtg attcttgtaa tataaattat aggattccag acagtaatac
    15601 aagtgtaaaa tttgatgtaa ctgaaaaatt aaatggtgtt gtaatatcta aaaaaaacta
    15661 tgctcttgat ggcaattata ctttaaatct tacagatgaa catttatcaa ctttaagttt
    15721 taactctaca aataatataa ctatagaact tagtacttat caagggggta agtttttaga
    15781 aaaaacggtt acatttacaa aaggtaatac taaaccaaaa ttaaatataa cttcttataa
    15841 ttcaactact gcaatcttta cagcaataga catagataat aacttgtcta aaatagagtg
    15901 gttcattgat gatgtattaa aagaaacaat aacaacagat ttgtatttag agaaaacaat
    15961 caactatgaa cttacagaca atgcaataca cacattaaaa atagttgcta cagatgcaga
    16021 aaatgcaact gttgagaagg ttttaagtat aagcaaagag ataatgccac ttcaagaaga
    16081 tgctagttta agtgatatat caactaagtt agcagagatt ggagaagagt ttagaaatgg
    16141 taaaacaagt attataaata ctttagcatt aaagaatata gaagcaagtt tgaataacac
    16201 acttgttgag ttatcagaga aaataaaaac aagttttgat agttcagacg ctagtgtgca
    16261 ggatttgcaa aatagaataa cagaattgaa taatcagctt agtcaaagaa aaaaatgggc
    16321 tacaggtaga tatacattta cagatttaga tatttcaaat tttaccttaa actctgaatc
    16381 aattgttcag acgaaatcaa ttataacaga tttaagtttc acaccaagta taataataat
    16441 tgattctata caaatgaaaa gtggaactga tagagtttat tttcgatcta taacaaattt
    16501 agatattact attggtgcaa aatatacaaa ttcatccctt ccagtaggag gaagtggata
    16561 tatttatata caaaaaccta cacctagtaa taatttttta ttaattttaa ccagattaga
    16621 tggtcaggga agagaaataa gctttagtcc aattgttggg gagactttga catggtatgc
    16681 atttgaataa taaggaggta ataaaatgaa tagaggaaat agaataattt ataatcaaga
    16741 cggaaagata ttactccaaa caggagaagc aacaggagat atattagaac acgacacaat
    16801 aacagaatta aatttcatag atttagaatt tggaagtata gactatagta aacagtatat
    16861 agagtctata aatccagtta caaaagaacc agttttaaaa aatatagaga ttgttttgac
    16921 taatgaacaa aagagattag aagtattaga aaaagagcta agcatgttaa aagaagaaaa
    16981 taaaaataga gatagtgaga tagtaaacac tgcttttgaa atagaaaata taaaattaaa
    17041 taataacata taggaggaat taacatgtat aatttattaa aacttatgat agaacaaaag
    17101 aactatagta ctaaagagga tttgcaacac aaaatggatg tattctatgc agtaaatagg
    17161 attacagaag aacaatattt agaactaaca agtttattaa agaaagaaga aataccagca
    17221 gaaccaacag tttaagagag gttctttttt tatttctaaa aatatataaa ttcatttaca
    17281 ttttgcctac acttcatcta cactttgtag acgtttatag ttttaaaatt aggtacaata
    17341 aaactataaa ttaagaaaga ggtggattaa atggcaacag tttatgaatt taattataca
    17401 ggaagtgaac aacgtgctac attaaaaccc ggcaagtata aattagaatg ttggggggct
    17461 tgtggtggta gatataaagc tgatgatttt actacttgtg caaaaggtgg ttatgcaaaa
    17521 ggtgaaatta tattaaaaga gaaaactaat tttcgtattt gtgttggtca gtcaggttat
    17581 gaaaaagttc tatctacttc ttcttttact agaactggtt ataatggcgg tggtgctggt
    17641 ggatattcta attttgctcc ttacaaatgg tcatttgatg gtggtggttc aactgatata
    17701 agactttcta gtggtaattc ttcttgggat gatttagaag gtttgctttc acgtatactt
    17761 atagcaggtg gtggcggtgg tgctagtgaa tcttctgtta gtaaacttgg tcatggtggt
    17821 ggcttaaatg gtgataacgg aattggttat caaggtaatt tcgcaggtgg tggcacacaa
    17881 tatcaaggtg gtattaataa tagttcagat tttgatggtt tatttggtaa aggtggtagt
    17941 tataataaac atataggtgg tggtggtgga tggtttggtg gtgcaggttg tgttacaact
    18001 caaagtgctg ctggtggtgg aagtggttac gcactaacta aagatagtta caaaccacaa
    18061 ggatatattc catcatcaga atattggcta gaaaatgtag ttatgaccgc tggaggtaat
    18121 actactaaag cggatggtta tgctaaaata acattactac aagcattacc atttttgaat
    18181 atatcctcat ataattccac acaggcaata tttaaggctg accacacaga ccctacacta
    18241 ttaactaaga tagaatattt tatagatgat acattaaaag aaactataac aacagactta
    18301 acaacagaga aaacaattaa ctatacatta gaagataatg ctctacacac acttaaaata
    18361 gttgttacag acaatgccaa tgctacagca gaaaaagttg taagtataag caaaaatata
    18421 atgccattag aggatggtgc tagtttacag gatatagcaa ctaaagttag cgaaatgaaa
    18481 gatggcttaa aaagcggaaa aagaagtatt gtaaatgtat taacattaaa ggatatagat
    18541 gcaagtttaa acaatacatt tgttgaatta tctgaaaagg taaaagatta ttttgataac
    18601 gcagattatt ttttccaaga ggctaacaaa ggaaaagaat taattgcaac taccattggt
    18661 tcacctgcaa caaaagaaaa tacttatcaa gaattatcaa gttatataac tgaatttaaa
    18721 aatactatag gtacactgac tactcaactt gaaagtgcta acaataaact gacagaccct
    18781 tatattacaa aagtgaataa cagaggtgtt ccaagtactt ttacagttga ttttcgcatg
    18841 tattatccat catcatcatt tactcgtaga agtacttgta tatatgttga tgctactttt
    18901 attcactata ctacaccagg agatatgagt acaggtgttc ataaaagtgt taaatatgtt
    18961 aaaactgata ctaaagattt gaatggttat cgaatatttt atgatggtga tggaactctc
    19021 agcttaactt atgaaaataa ttctgtgagg gttgttatac aaggaggata tacaagttca
    19081 cctggaagaa aaaaatctga tgtttattct tataatgttc gtatggtgaa tacttattgg
    19141 gattaataaa gatattaaaa aagtataggt gtttgtatgc caatagaatt aaataaaaag
    19201 agcttagata attctaagtt ctttttttat gtaaaaatta ggaggtagta tggaagaaat
    19261 cagcataaat ctattatgtg cagtagcagg ggttataata tcctacttag catttagaaa
    19321 tagctcaaac agaaagatac aagatgaaac agaaacaact acaaaattag aacaacaaac
    19381 aacttttctg tgtgagaatg taagagatat aaagcatgat gtagcgaagt ttaatactag
    19441 tttcttagat attagtgaac gagttgcaaa agtagaagca agtacaaaac aagcacatct
    19501 tagaattgat gaaattataa atagaattgg aggaaaataa aagatggata atttaataag
    19561 ttttatacca gagcagttgc taattttagt agctgctctc tctattatag gcaaaggttg
    19621 taaaaaatat aagcaattag ataataaata cattccaatt atattacttg tgttgggaat
    19681 tggattttca atatggatgc taggatttaa cccttcatca attttacaag gtattttatg
    19741 ttggggagtt gcaataggag caaatcaagt ttataaacag ttgaaggagg aaaataaata
    19801 atgaaagtag tagtagtacc aggacataca ctaacaggaa aaggaacagg ggcagttggt
    19861 tatatagatg aaggaaaaga aaacagaatt ttaactgatt taattgtaaa atggttgaaa
    19921 caaggtggag ctattgtgta tactggaaaa gtagataaat ctaataacta tttagcagaa
    19981 caatgtgaaa ttgccaatag gcaaaatgta gacttagcag tacaaatcca tttcaacgca
    20041 aataaaacaa ctctaaatcc tatgggtaca gagacaatat acaaaactaa caatggtaag
    20101 gtatatgctg aaagagttaa caaaaaacta tcaacaatat ttaaaaatag aggtgcaaaa
    20161 tcggacgcaa gaggtcttta ctggcttagt catacaaaag caccagcaat attaatagaa
    20221 gtgtgcttcg tagatagtaa agcagataca gactattata tcagacataa agacatagtt
    20281 gctaaattaa tagcagaagg tattttaaat aagacaatag ataataaaga gaatggtgag
    20341 gggaaaatca tgtacaaaca tacaatcgtt tatgatggag aagttgacaa aatccctgca
    20401 actgtagttg gttggggtta taatgatggg aaaatactga tatgtgatat aaaagattac
    20461 gtaccaggtc agacgcaaaa tctttatgtt gtaggcggtg gagcatgtga gaagataggt
    20521 tctattacta aagagcatta cacaatgata aaaggtaatg atagatttga tacactttat
    20581 aaggcattag attttattga tagatagatt gaggattgaa taaaatccat ttacactttt
    20641 cttacatttc atttacactt ttaatacaaa tatactataa aaatacgata taattaagac
    20701 agttaaattt ataattaata ttagtaagaa tctttaaaat aaatatagca acaggtatat
    20761 cataacaaat aaatgacgag aattagagat agttaatcat gaggataact gtctcttttt
    20821 tattgtcgaa taaatcagag agtgaaggga ttgaatagaa tgagaaaact tgataatatt
    20881 aagaagggca ctataatttt agacataatt cctaatagtg caaatgggag agatgcaatg
    20941 aaaattgaaa aaattgaaat taaaggtatt ggtggaataa aagaattaag tctgaggttt
    21001 aataaaggac ttaatataat atgtggtgca aatggtatag gaaagacaac tattttagaa
    21061 gttatttcac atcttttttc tatacaatct tctgatttaa agaaaaatgc aaaatttgat
    21121 ttaggagaag caatagcgga ttattcgttt gaagatatag aagctgtaca taaaagtact
    21181 tatcaaatca atgatttcaa tgcttctgtg aaagaactta tttttgataa tcgagataaa
    21241 aaaaaatata gtaaatttgt gttgtttttt aagacacata gagaattaaa ttattcaaaa
    21301 ttggatggaa taactggaga tgaaacatat agtgatgata gtacatctta tatggctgat
    21361 ttaggtatag attcaagtaa aataaaaaat tggtttatta atagacttct tttttctaag
    21421 caagaaggtt ctcttacaaa agaacaatta tgtaatttag acttagcaat agaaatgatt
    21481 agtattttag ataagaatgt atcatattct agaattgtat cagattcttt agatttaatg
    21541 ataaatactc ctcaaggaga aatttatata gaatatttat catcaggata taaatcatgt
    21601 ttttatatat tattaggtat aattaaggaa ttagaatata gatttactaa accttatatt
    21661 gaagttaagg attttgatgg tgtcatacta attgatgagt tagacttaca tctacatcca
    21721 gaatggcaag ttaaaattgt aaatgcatta aaagtattgc ttccaaaggc acaaattata
    21781 gcaacaacac atagccctaa tatgatacaa acactatcac cagatgaaat tataccatta
    21841 accatggatg aaaatggtaa tgtgcgtaaa aaagacttag agttaggtga atatggattg
    21901 caaggatgga ctattgaaga aatattgaca gatgtcatgg gaatgaaaac aacttcttct
    21961 gagttatatt tagatacaat gaaaaaattt gatagagcta tggataaaga gaatgtagat
    22021 gaaatcaaga aatactatga tatcttgatg aaaatgttac atccaaatag tacacttaga
    22081 acaatactga aaatacaagt ggcaggaata atagattgat aaaaataaat agaacaagaa
    22141 agcctattga attaacagaa gaagttcaga aacaattaac agaagaattt aaaaataata
    22201 aagaaaaaag cgtgtggagg aaaaagtata ttacaaatgc tctacttgag atgtctcatg
    22261 gaaaatgttg ttattgtgaa atgaaattga tagaagaggg caaatcactg aatgtagagc
    22321 attttcacca caaagacaaa tatcctgatg aagtagtgaa atgggaaaat ttattgccat
    22381 cttgtgggag atgcaatagt gaaaagggta ctcatgacac taaattagaa cctataataa
    22441 atcctgcaat aaataaccca aaagattatt tatatttata taattataga tataaaagta
    22501 aaaatagaaa taaacttggt agtgatacaa ttgatatatt atatttgaat gatacagaca
    22561 aattaattaa accaagagta aatatttgca tggctttatt caaaaggtta gagtctataa
    22621 aaacatttgt tgaagattat caaaatggta caggaacaca tacaagaaga aaaaataaaa
    22681 ttataaacga agtaaaaggt gtattaagat gcgctcaacc aactgaagaa tatagtgcta
    22741 ttgtggcaaa tgttatagta aatgatgatg attataaata cataaaagaa ataatgtcag
    22801 aatttaactt gtgggataat gaactagaag aattagaaag taaagcaaaa gaaataatgt
    22861 tagattcaga atgaaataca tattaaaata actagataca attaaatttg aaagtataaa
    22921 aaaagaaggt gataaaaatt tctttatcat cttctttttt tatactttct ttctttaagt
    22981 tttttctttt tcatatcttc taatacatct aatgcagtag tataaaattg tatttcatct
    23041 ctgtaaggca cagctatatc aagagatgta ttaatagcta taaatatgag cactattata
    23101 gatgaggatt gcagaattaa atttatataa ttatctttaa tatttaatga acttaaaaat
    23161 aaattagcaa gtaatgaaaa aacaacagcc ataagggaga aaaacaatgc attaccagga
    23221 ttattatttt tctctaactg acctttaatt ctagtttgct caatttctat ctttctaatt
    23281 gtattaatat tcttaatttc attgtaatga ttataaattt ttgtgtaata ttcttgataa
    23341 tttattacac tttctttatt tcccttaaag tattttatat ccttcttgat ttgttttttc
    23401 ttttttatat ttttaaacca atatttcaaa ctcataaccc ctccataaat ccatataata
    23461 tactttaatt tataacacac ttaataatat atatcagcaa tttgtcgaac gattttaaat
    23521 aaaaatagag ccaggataca agagaaaaat ttacagagat ttattctgat gatgtgtggt
    23581 caacaatgga taaggctaga taatttgtaa agacaaaatt ataagtttta tatttataaa
    23641 gataaagctt tgatatattt catccataat tttcaaagac ttatataaaa aggagtgttt
    23701 tatttttcta aacactcctt tttatataag tctttcaata atcaattttt aaaattaata
    23761 atattgctat tatttctttt tcaagtttat agtttcttca tttttattcc aagatataat
    23821 tactttataa ttagattccc tatttgaata aagacctggt ctttgtcttt ttattatttt
    23881 ttcttgacct gattctaaaa ctgcatcttt taaaattata attgcatctt caccatctat
    23941 aaactcatat gaataattaa atttttgctt aactacatct ttactgtctt tatattttat
    24001 ttctaattct gattgttctt cagtagtaac aaatttagct gtccaatgtt ctgattctcc
    24061 aataaagata tttttatcat tttttatatt aagtacaact atcgcagcga ttactaaaac
    24121 tataaaaata cctagaaaaa gtttttttct catactgagc cctcctttga ataattatat
    24181 gtattataac atgaaaacag ttatccaaca tcattattat gaattttctg aattttttga
    24241 tatttatatt ctatcatgat agaatatgtg gtataattaa taaaaaagga gggattagta
    24301 tgaattctag gtttaaaaaa tctgcaacaa gtattttatc tttacttgca atgacaatac
    24361 tattaccagc aagtgtaaat gctagtgaag tagaaaattc atctatgaaa gtaacatatt
    24421 cagagaaaca agtaacagat atgaacaagt tatatgatat ggctaaaaat ggaatcactg
    24481 atgttaaaag tcccaacgaa aaaggtataa tcaaaaatga aagaacagga gaatctatgt
    24541 atgttgatgc tatatcaaca acacaattat tagaagtcaa acaatctaaa gatttaacat
    24601 ctaagatata ttctaaaaca gtttttttag atactgatac aataaagccc cttagaaaag
    24661 caagtatatc agaagacgga tgggataaaa ctggtggtgt aaaagcatct ggtacagtta
    24721 catatacaat atcaaaagga gatggagcat tccaatatat ttctgtcagt aaagtttctg
    24781 gaaactggtc tattgcagat ggtcagattc gtgtaacaaa tagaaaggtg tacataaacc
    24841 aaactggatt tgtttctaat ggattaggaa ttaagcaaca acaaaggaaa gacccaacat
    24901 caaattcttt ttcatataat gcaccttcta gttggaaacc agtgggtaga gattctcttc
    24961 aatataattg tgggtttgaa tcaattgcaa cattagtaag aggaggaagc tcttggtcat
    25021 tcaatttcat cgttcaacct taaaacattt taagtgaatt ttattaaaat taaagatata
    25081 ttgacaccat aaagatataa taaaaaataa aattatagta aaaattgtaa taataaagcg
    25141 aacgaaaatt atcatactaa aacataagac atgttataat tgtattatat atacattaac
    25201 atacaccaaa gcactcttat aaaaagagtg cttttagtgt atattttttt acttttttga
    25261 atgatttttg tcgtatgaat atattctgaa taaggcttta tgataaaata aatttaaagg
    25321 agtcttttta tattaaaaat taatatttta aatatttaga atttataaaa ctttagggag
    25381 ataaaactga tgttgttagg agatgaaatt aagttgaatt tagagccaag tgatttaata
    25441 aattctatac catactttaa atctgaatat tcagatttat gtggtttaga cgcagatttt
    25501 ataaaggaac agttattgaa agctgaaaat aatgatagaa tagtgagtat ggctcgagga
    25561 gaaggaagag catttgttgt ggaaccaatt attaagcgta ataattattg caaatttaga
    25621 aataattcat atgatatttt taattcaatt ccatcttatg aatatgcaat aaaaataata
    25681 gaacgctata aaaaccatat tttcaatcca actgaatatc gcaacagtgt aatgagaaga
    25741 gtaggaacat atgaaaatga tattttcaat tggggataca aatcaatgca ctcttatatg
    25801 gaatcattac ctttaagaga atttttagag ccaaataaag ttgatagaac attattattt
    25861 gagtttcttg attttatgag agaacttttt tcatatcagt taagaacgta tccaggacgt
    25921 tttgataatt ccaaaacttt agatgccata gagaccataa aaaatgctat cataaaaaca
    25981 gaatcacatg atgatttgct tataattaaa gaatggttat gttttttatt gcatactgga
    26041 aatcatagag tatttaaaaa tataactcca tggatttcat tgtctacagg aagcaaaaga
    26101 tataatattg tacataaatt tgcttctcgc aaaccattta cttcttatag aacaatatct
    26161 gagaaacata cttataacga aaaagaaaag tttatattta ttgattattg ggagtatgta
    26221 gataaggaaa atttaacttt taggaataca aattacattg tcaataaact taaaagtatg
    26281 ggagtaaatt ggtatgaaaa tagaaataat gaagttatgg taaaatatgc attatttcct
    26341 caacaaatta tagggtatta ttattttgag aatagaaaat tacaatatta ctttattaat
    26401 cctcattatt tgaaagcatg gcaaaaaaat aaagatttta aaataggaga tgaactgtac
    26461 ataaatcaag aacaagtagt gtttcctttt aataatccgt atagagtaat atacggaaaa
    26521 aaatatggac atatttcagt agttgataag agataaatat ttttaggctc taattataaa
    26581 taaaacaata ttatttatct ttttttaaaa ttaatgacat aaaaatatat cttatatatt
    26641 gttatcaatt attaaataaa tcttatattg catatggaat aaattggaaa atatacttat
    26701 cctaatttaa ttgattacat actattatta gtataaaatt tagttataca taaattggta
    26761 agaggtgtaa actaatgaag attaataaat taccacatgc agaactaaaa ctaatgaagt
    26821 atatttgggg agtagatgat gtattagcct caagagatat catagaagtc atgaagttga
    26881 agtatgattg gaaaaagagc acaacattga catttttaaa aaatttagta gataagggct
    26941 ttttaactac tgataaggta gatagatgta cgcattatac tatagctata aaagagaaag
    27001 attacttaaa agttgagaca aagagttttt ttagttttat gcataacaat tcatttaaga
    27061 gttttatttc agcattacat gatgatgaag ttttagatag taagagcttg gacaaattag
    27121 aagaatactt taaaaatttg aaagaagaag atattgatga ctaataaagc tatcagtatc
    27181 tttttagttt gagacaattg agagtagcgt ttggatttaa tgttagtttt atgtgatggt
    27241 agaacattat ataaagaaaa gtgcttattt ccttagtatc tgatagtaaa aaaaaatata
    27301 gaaaataata ccaattaaaa tttaaagata tatgaaatac tacaatagct taaatcatgt
    27361 aaatatgata aagatattga aattataaaa ggaatataat tttagaagaa atagttgaca
    27421 gataaattac cttactatat tattgtatta ataaaatgat acaataatat agtaaggagg
    27481 taataaatga aatctagaaa acataatatt acaaaaggat tatttatagt ttacataatt
    27541 attttaacat ggataatact attcaagttg caatttgata tctcatccct tgaaaccatg
    27601 aatcttagaa gcataaactt agtacctttt gctgggtcac ttataattaa taatagagta
    27661 gatatatcag agattatatt aaatgtggct atatttgtac catttgggat atatgtgtgt
    27721 atgctaaaag aagaatggag ctttataaaa aaagttatac ctatttttat aactagtttg
    27781 gcatttgaaa cacttcaata tatatttgca ctaggtgcaa gtgatataac ggatttgata
    27841 ggaaacacac taggaggaat cataggaata gctgttttta tgctattatc gaaaatattt
    27901 aagaataata ccataaaaat tatcaatgta ttggcattga ttgtgacaat tattgttgta
    27961 ttatttttag gattagttat ttttgcaaac ttatagaaat aagtatatat gtttagctta
    28021 aaatagaacg taagatacag ttacatataa aattatttac acataaaaag cacctataca
    28081 ggtgctttcc taaattatta aagaattatt gtatcttgaa actcttgtat gttcaattct
    28141 tgattttctc ttgttttttc taataaatct aacgcacaat ttatacaaac tttaatttct
    28201 gcattggtat ttttctcata ataagttata tatttatttc tatatttatc tatttctttt
    28261 ccacaacgac tacacattac aattacgctc atatcttagt tcctccatct ctaattattc
    28321 ttaatatatt caatagtatc acttttctga aaataatgat tgttaaaact gtatcaaatt
    28381 tagatttact ttttattata atgcatttta ataaaaaaat aaaggttatg ggtaaaatat
    28441 ttatagaaaa aagtatatta ttgaatagat tataaaattt tattattttt tagcagtatt
    28501 aaatacacat taatatctat aaagtgacaa aataaaaaat actatttaaa tagatattaa
    28561 aaaattgata ccaagtattt gtttgctata tgaataacaa tttatttagg aactttactt
    28621 taacactgta taataataaa gtaattgcta aaaacgtttg atgatttgga tgtattttta
    28681 gaaattagaa aaatatatac ttactgacta atgataatct tatatgtatt ttagtttgag
    28741 tgatttaaga aaagtgtttt gaaagggaat tattttatag agtaaataaa tatataatag
    28801 tagaaaatta catataaaga gtagtgttta tttcattacc ttctttatct gttccgatag
    28861 ggtcttgtag agatacttga gttttatttt ttttgttaga tctaatattc attaaaatct
    28921 cattttcaat acatctagaa gcatatgttg ctaatcgagt tcctttatct atgttataag
    28981 tttctatagc tttaattaat cctattgtac ctatggatat taaatcatcc tgatcttccg
    29041 ttgaattatt atatttcttt gctatataag ctactaatct catgtttctt tcaattaatg
    29101 tatcttttgc acttttatcg ttttctattt taaatttagt taaatactca atctcttctt
    29161 caggggttaa gggtttttca aaagatttaa gagctgccaa taggtcaccc ccttttcaac
    29221 ggtcacttta aattatatga aggagactta tccaagttga ctgttatcta ataaaataat
    29281 atgcatattt ttagaattta aaacatatat ttgcaaactt ttgaatggaa tatgacataa
    29341 agagtgggaa tttaaattta agtttttgtt gtatatatat gaaacaaggc gaagaaatta
    29401 ttgatttata aagtataaat tggaattgag gtgtcaataa atataaaagg aaatagtatt
    29461 tatatatgtt ttggtgttga agtaaaagat taatgcaaag tattagagtc tataaaaata
    29521 tgaatatagg aggtgtaatt ttacaatatt taaaaaagta aatgtaatta attgtttgta
    29581 taaagttgat tacaagcaaa agtatcagtc atagttaata ctgttaagga tgaaggtggt
    29641 gtgttaattt atatatgtat gggaagaaat tttgattaca atgaaaaaac ttacaaaaga
    29701 tatttacaaa aaaacttata gttaaatgtt tatatataaa atactattta ggggttgttt
    29761 ttattattga aaataagaaa gagtggtttt atatcaatcg aatgtataat aagtattgct
    29821 atattatatg tggctgttta tttagtttct acatcattgt ataattgtta tagttttatc
    29881 agtagaaata tatctgacag agaaatgtta agtacagcaa aaaaatatat agaagatgag
    29941 aagtatagaa tacaaaatag taagtatgag ttaattgaag ataagataga aaaaaattac
    30001 ataaatggat atgaaattaa cagtagaata gagcaaattt tagattatta tcaatgctat
    30061 gaaataaata tagagataaa aaatgaattt aaaaaactga ggtttaatag ctatgttact
    30121 agaaaataaa ggctctatat taataataac attgataata ttttctatta taagtactgt
    30181 gtgcattatg tgtataggtt taatttatac acataataat atgtttgagt taggatacaa
    30241 agacattcaa ctaaaagaaa tttctttaag tggaatagaa atatcagtaa gtaatgtact
    30301 ttcttgtgtt gaggaagcta ttgatgtatc taataatgaa gacgaattta gagaatatct
    30361 cttaggaaat aatatgattg aatgtataaa aaaaataaaa gatacatctt atagtagttt
    30421 agaagaactt tctttaaaag tagaaaataa tactatttat gacagaggag atttttttga
    30481 atttgatata gaaagtaatg ttagagaaaa agaattttta aaagcaataa aagtaagagt
    30541 gaaaatcaaa aatccatgga taggaattga cattgaagat tatatggata aatctaataa
    30601 caataaaatt gatgacaaaa cattcaataa ttataaagca tctgaaaata atgaaattct
    30661 aaatcaattt aaaaatgaaa gtgaaaatat aaggaatcaa gaggttggtg gatttacaga
    30721 agaagatgaa gaatatgaag aagaacttaa acaaaacata attgaaaata taaagaagaa
    30781 ttttgatgaa aaaaacctag tacaggtata taagtatagg ggtgtataac tttgaaaaaa
    30841 gaaggaatgt gactgtaata gaattaatag tatctatcag tataatactc ttgatagtta
    30901 cattatcttt tccaaaagat aatcttgaaa atcataaaat aaatttattt gcacgtcaac
    30961 tttgttcaga tataaggtat gttaggcgaa ttaatatgtt tagtaactac aatacatata
    31021 tatattatat aaatcaaggt aaacacgaag gttatgtatt gagaaaagat ggtaaaaaca
    31081 ttaaatcaat aatgctacct aaaaatgcaa aaatagctag gagtattgaa ataataaagt
    31141 ttaaatctga tgggtcgcct caaaaggcgt ctacaataga gatatataat aatagattaa
    31201 gaaaaactat aacaataaca cctgtaagtg gaagagtact tctgaaagag ggaaaatatg
    31261 aaacataaat atggttactt gcttttggaa agtgtagtat cattgtcttc aatggtgata
    31321 attatactag ttttatattc tatatttttg tctacaataa acttaaagtt aaaagtagaa
    31381 gataagatag aactacaaca acaaagtctt gaaatcataa aatctatgga aggaattatt
    31441 ggcaattcta tgggaataat gaatatatct aattatgaag aaacatttaa aaagacaacg
    31501 tctataaaat gtagatatgt agatgaaaat aataatgaag aaggcataag taataaagaa
    31561 attatattga atgaaagacg aaataagtta tttgtaaatt ctttaaatgg cgaaagtagt
    31621 caagcaggtg gttatgaaat tggagattat gtagatgaaa tgtatgtatc aattactaat
    31681 aatggtcaat atgttaatat taaattgaaa ttatcaaaac gtagtcaaaa atatgagact
    31741 gatttcaaaa taaaagtatg gaattttagt gaaagtatat aaaaatacat aaatttaaga
    31801 gaaagaaatg acatcaataa gtcatataaa atataattat tgagaactat ataactaaat
    31861 aatatcaata tgtaaagtgt atagattaag aatatagagg ataataataa aaatatagaa
    31921 taagtaattt gccaaatact tgtttatatt gtataactta tgatattatg atattagtaa
    31981 aaatttgtaa tcctgacttg acagaattca agtaagagat ataattttaa aggcatagta
    32041 atgtaaaatt tactaaaaaa taagaaattt attttaatat ggaggaacaa aaaatggtat
    32101 cagcaggtga ttttagaaaa ggtgttacat ttgaaaaaga tggacaacca tgtttagtag
    32161 ttgattttca acacgttaag ccaggtaaag gagctgcttt cgttagaact aaatacaaaa
    32221 acttaaaaac aggagctata agagaagaaa gtttcaatcc aagtgaaaaa ttccctaagg
    32281 ctgttataga tacaagacaa atgcaatatc tatacaatga tggtgagtta tattatttta
    32341 tggatcaaga aaattttgaa caaataccat taaactatga gcaagttgaa gatgcaatta
    32401 agttcttaaa agaaaatgaa gttgctacaa taagatttta ccaaggacaa ccattccaag
    32461 tggaagcgcc aaactttgca gagctagaag ttacagatac agagccaggt ataaaaggtg
    32521 atacagcaag taatgtaact aaagcagcta cagttgaaac tggagcagtt gttcaagttc
    32581 cattatttat aaatactgga gataaagtaa agatagatac tagaacaggt gaatatttat
    32641 caagagtata aaaatttatg tatataaaag cttatatgtc ttaataatat aagatatatg
    32701 agcttttagt ttatatataa aaaagaaagc gaggggtgtt acatgaaaca tttatatgaa
    32761 gaagttgcat acttaaaagg cctagcagaa ggactagaaa taagtgctga aagtaaagaa
    32821 gggaaaatga tacataaaat agttgatgca ttagaagtat ttgcagatgc tattgtaaca
    32881 ttggatgaag aacaagaaga acttcaagat tttgttgaat ctatagatga agatttagca
    32941 gatttagaag aagatattgc tgacatggaa gaagatcttt atgaagaaga tgacgatgag
    33001 gatgatgagg acttcagcta tatagaaatg gaatgcccaa attgtggaga gttagtagaa
    33061 atagacgaag atttgttata tgatgatgaa gtagatgttg tttgtcctga ttgtaaggct
    33121 gtgatattat catcagaaga tgattgtgat gatgattgta catgtggtgg ttgttcaagt
    33181 tgtgatgata gagagtaaaa attcataaga attaaaactg cctatgatgc ctatgagata
    33241 ttttgcttca taggtagttt tatttttatg aggaagggta ttatgtattt tggttttgca
    33301 atacttggac aaaaatagta cactagaatt tatagaatag gattttggag ggatgtaaat
    33361 atgaaaataa gtaaaaaatt actagataat atacaaagat ttgaaaatgt tataaattat
    33421 aaatttaaaa ataaagaata tatactagaa gctcttactc atagttcata ttctaatgaa
    33481 aataaaaaat ataattttaa cgaaagattg gaatttttag gggattcggt tttaggcata
    33541 gtgataagtg attatttatt taatgaagaa gctaatctgc ccgaagggga actaactaaa
    33601 cttagagcaa atatagtctg tgaagattca ttaagtgaag tagctaatga tataaattta
    33661 ggtattcaca tgttattagg tagaggagaa gaagcaacag gaggaagaca taggacttca
    33721 atattagcag acgcatttga agctgtaata gctgctatat atcttgatgg aggttttgaa
    33781 agtgcaagac agtttatact tcatcatatg gaaaatataa tttatgattc aagaaaagga
    33841 aatatattta gagactacaa aacgcatctt caagaggtgt tacaagggaa tggagaaaat
    33901 aatatctggt acaggcttat agaagaaaaa ggaccagacc ataataaaag atttgtaatg
    33961 gaagttggaa ttaatgacga tgtacttggt ataggagaag gcaagagtaa aaaagaagct
    34021 gaacagttag ctgctaaaat agctttaaag aaaaaattat gggaaaaata aatataatat
    34081 gtaaaaatat aaaaagaaat atttatatta gaaggatgtt gtagatgaaa aagagaatta
    34141 tacctatatt tgttcctcac aaaggatgtc ctcatgattg catattttgt aatcaaaaaa
    34201 aaataacagg tgtgagtact gatgttacta gtgaagatgc aagaaatata attgaggaat
    34261 gtttagagac tatagataaa gatgcagatg tagaaatagc attttttggt ggtagcttta
    34321 ctgctataga tattgatata caaaaaagtt tattatcagt tgctaaagaa tatgtagaaa
    34381 aaggtcttgt aaaagatatt agaatgtcta caagaccaga ttgtattgat gaagatatat
    34441 taagtatgtt aaaagaatat aagacaagta taattgaact aggagtacaa tccttagatg
    34501 aaaaagtatt attagatagt ataagaggtc atcaatctga aattgtatac aagagttcaa
    34561 agatgataaa aaatagtgga atcaaacttg gattacagat gatgattggt cttccagctg
    34621 acacagaaga aaagtgtata tttacagcaa aaaaatttgt agagctaaaa ccagattgtg
    34681 ttagagtcta tccaactttg gtagtaaaag atacaggtct tgaaaagtta atggaacaaa
    34741 ataaatataa tccatttact cttgaagaga gtgtaaatat agtaaaaaaa gttcttgtac
    34801 tgttttatgt taataatatc aatgtaataa gagttgggct tcaagctact gatgatatac
    34861 aaattggaaa agctgtttta gcaggaccat atcatcctgc atttagagag ttggtagaag
    34921 cagatatgat aaaagattat ttagaatttg ttatttttca aaataaaaat ataaagcaaa
    34981 tgttggtcaa atctaataaa aagaatattt ctaaaatcat aggaaataaa aaaacaaatg
    35041 ttaaatatat ggaagaaaaa tttggtgtgc ttttaaaaac acaagaatca gatttagata
    35101 taaatcaatt agaaattgtg ttagatggga aaagtttaat tagtgctaat atgagagaca
    35161 ttcatagaaa attgtatgac atttatgacc tttagtttta ataatgaagg gagagaaaag
    35221 atttgtattt aaaaagacta gagttaaagg gatttaaatc ctttccagta aaaacagata
    35281 ttatttttaa agaaggaata acagccatag taggaccaaa tgggagtgga aaaagtaata
    35341 tatctgatgc tgtaagatgg gtattaggag aacagagtat taagagtctt agaggggata
    35401 aactcgaaga tgtaatattt gcaggtacag atacaaaaaa acctatgaat tattgtgaag
    35461 tggctcttac tattgataat tctgaaaatc aattggaatt agattttaca gaagtaacta
    35521 taagaagaag ggcttataga aatggtgaaa gtgaattttt tctaaataat aaaagttgta
    35581 gattaaaaga tataaaagaa gtctttttag atactggtat tggaaaagat ggttattcaa
    35641 tcatagaaca aggaaaagta gatgaaatat taagtaataa tcctttaagc agaagaaaag
    35701 tttttgatga agcttgtggc atatcaaaat atagatataa aaaacaggaa gcagaaagga
    35761 atttaagtaa tacaaaggaa aatttagaaa gaatagatga tgtatatata gaaattgaaa
    35821 atcaattaaa gcctcttttt aatcaacaga caaaggcaaa aaagtacttg gaaataagtg
    35881 aaaaattaaa gacacttgaa gtaaatagct ttataagaga aattgaagga atagaaaaag
    35941 aattaagtga ggttaatgaa catcgtaatg ttattgaaaa ggagctcaat gaaaaagaag
    36001 aacaaaaaaa tgttgtagag aaaaagcaag aagatattaa taaagaggta gaggtattac
    36061 aagatgtaat tgaaaaatct gtagattata taaattcaat taaaggagtt atatcaaaaa
    36121 aagaatccca aataaattta attaaggaaa gaataagaaa ttttacgaat gaaattagta
    36181 gaaaaaattt agaaataaag gatataaaag agaagctaaa tgaaaataag caatacataa
    36241 aagaattaga aagcaataaa ttatcaggta gtgaagaact atctaccttg caggaaaata
    36301 taaaagtatt ggaaggaagt aaagataaac aaaaaattaa gttagaatcc ctaaataatg
    36361 agatagaatt attgaaagaa agtataattg atatattaaa taagaaacaa gagtttagta
    36421 ataagctgtc tactttaaac gcaaataaag aaaatatgaa tatcagagat gaaaatataa
    36481 attcagagat aacagagtta aacaaaaata ttgaaataaa atcatctgaa ttagatacta
    36541 taaataaaga atttaatatg caaaatgaaa atttaaagaa tgtaaataat agacataaag
    36601 aattatcaat taatttgcag gattcaatta gtgaacacaa taaactagaa gatgaaatac
    36661 agaaaagtaa atataattta aatggatata attcaaagtt aaatgtctat atagatatgg
    36721 aaaatcatta tgaaggattt aatagaggag taaaagaagt actaaaaaat aaaaatttaa
    36781 aaggagttca tggagcatta ggacagatta taaatgtacc tgaaaagtat gagaaatcta
    36841 tagaagcagc tcttggtgct tatatgcaaa atataataac tgataatgag tttagtgcta
    36901 agtctgcaat aaactatcta aaacagaata atttaggtag agtaacattt cttccattaa
    36961 atataattaa atcaaataaa ataagtctag gaaatttaaa agcaaatact aagttcatag
    37021 gaatagcaag tgatttaatt acatttgatg aaaagtatag aaatataatt gaaaatatac
    37081 ttggaagaac aatacttata aataatatag atgagggcat aaaatttgca aaagaaactg
    37141 gtcataggtt taaaatagta actttagatg gtgaaatctt aaatccagga ggttctttga
    37201 ctgggggaag tctaaaaact aatgggaata tactatcgag aaaaagatac attaatgaat
    37261 atacagaaaa gataagtaat atcaagaatg aaatttcaca tctagaatta aaaagagaat
    37321 ctttagacaa agatgtgaaa aatatcaaaa atgaaattga ttcacatgaa agtaaaataa
    37381 aagatttaga aaaaagtata ataataaaaa gtacaagtat aaagaatgtt gagtctgaaa
    37441 ttgaatcgtt aaaaggtagt attactaaat tagaaaatga gaagaatgat ttaaattcta
    37501 acctaaatta tacacttgaa aaaagtgatg atgttagaaa agatatggaa gagttagatg
    37561 atttatacaa taaaaataaa gaaaaaattg atgcattgaa tgaggaaata aaaagataca
    37621 atgatttata tgataaagaa aaatctgaat ttgatgaatt gaacttaagt ttagtgaaga
    37681 aaacagaagt ttacaatagt atagttagag atataaaaag aatatctggt gaaaattgtg
    37741 agctagaaga aaaaaataaa caattagaag agtcattaaa ttatgaagaa catgaaataa
    37801 ttaaattaca agattctata ctcactgaag aaaaagaaaa agaaaattta acaaaacaac
    37861 taggggatag taatagaaat cttgaaacta gaaaaatagc aaaagatgat ttaaaaaata
    37921 gttttgatga aattaataaa gaattaaaaa ctatagatag acagcatata gaacttaaag
    37981 aaagtttatt taaagttggt ggaagattag aaagattaaa aactagtcaa gacacatata
    38041 taaataagtt gtttgagcaa tatgatatga ccttagtaca agcattggaa attaaagatg
    38101 aagatttgga tatagataga aaattcttag aaagtctaaa gagagaaata agaagtcttg
    38161 gaaatataaa tatagactct ataaaggaat atgaggaaat aaaagaaaga tacgattttt
    38221 atagcgaaca aaagcaagat ttagaagagt ctatggaaga gatagaaaaa cttatacata
    38281 ctttagaaga aaatatgaaa tctgaatttg aaattaagtt tgaagaaata agtaaaaatt
    38341 ttaaatatgt atataagaga ttatttggtg gaggttgtgg agaattaact attttagata
    38401 aagaaaattt attagaaagt gatatactaa taacagctca acccccaggt aaaaaaatga
    38461 aaaatttaaa cctattatct ggtggagaga aagctttaac ggcaataagt atattatttg
    38521 ctatattgat tacaaagcca acaccatttt gtatattaga tgagattgaa gcgccacttg
    38581 atgacgcaaa tatatttaga tttggagaat ttttgaagga tttatctaaa gagactcaat
    38641 ttatatcagt aactcatagg agaggaacta tggaagctgc tgattatatc tacggagtta
    38701 caatgcaaga aaaagccatt tcaaaagtta ttagtttaaa attaaaagaa gctcaggaaa
    38761 taacagatat tatataactt agattgacat aggaggaata acagtgttaa aaaaattatt
    38821 tggttttgga aaagacaagg aaaaggaaat agaaaaaaaa gatgctgaag aagaaataga
    38881 agttgaagac agtgttgata atttagaaaa cttggaagaa actatttttt caggatttga
    38941 agaagaagtg atagataaag tggaagatgt tgaagaaaaa aatgaggaaa gtgtcaataa
    39001 tgaaggcact gaagaaatcg aaaactttga aaaaatagaa gttgagatgg atagtaatgg
    39061 aaaagaggta gaaaatattt caaataatga ttctcaagaa gagatagtcg aagaattaga
    39121 aaattatgat gaaattgagt ctaaagagat agaagataaa gaagataaga aagttaactt
    39181 gtttgaaaga ctaaaacaag gattgacaaa agcaaagcaa ggaataactg atagaataga
    39241 tgaagtttta aaatcatata caaagataga tgaagaatta cttgaagatt tagaggaaat
    39301 tttaataaca gcagatgttg gtgtaaatac aactatggat ataattgaaa gactaagaga
    39361 taaaataaag caaaaaggta ttactgaacc aataaaggta agagaagaac ttaaatctat
    39421 agttgaagat attcttacaa atgaaaactc tacactagat atagaaccag caccatgtat
    39481 aatattaatg gtgggtgtaa atggggtcgg taagactact acaataggta aactagcaaa
    39541 tagatacaaa aaagatggta aaaaagtttt attagcagca gcagatacat ttagagcagc
    39601 agcaacagag caattagaaa tttgggcaaa tagaaccaat gtagacataa taaaacatca
    39661 agagggagca gaccctggag ctgtagtatt tgatgctata aaagctgcaa aagctagaaa
    39721 aacagatgta ttaatatgtg atacagcagg aagattacac aataaggcta atcttatgaa
    39781 tgaacttgga aaagtattta aaatagtaga tagagaattt ccagaagcaa aacgtgaagt
    39841 acttcttgtg gtggatgcta caacaggtca aaatgcagtt gttcaagcaa agacatttaa
    39901 agaagttgca gatataacag gtatagtact tacaaaactt gatggaactg caaaaggtgg
    39961 agtagtcctt gcagtaaaat cagaagtaga tgtacctgta aaacttattg gagttggaga
    40021 aagtgtagaa gacctacaag atttcaatgc aaaatcattt tcagatgcat tatttggtaa
    40081 ctaatgttct tttaaaaata atggttgaca agagtgttgt tatgatataa aatacaatag
    40141 tgtaaagtaa ataaccttta cagtatactg ctaggaagtg taagatatga atatagaaaa
    40201 aatggtcgaa attggattgt tatttgaaca gtataaagaa ttattaactg acaagcagaa
    40261 agaaatagtt gctctatact atgaagaaga ttattcttta ggtgaaatta gtgaaaatct
    40321 gaatgtatca agacaaggtg tttatgatac cttaaagcgt tcagaaaaaa tactaagaga
    40381 ttatgaagaa aagttacact tagtatcaaa gattcaagag caggaaaaaa atattaagat
    40441 tataaaagat aaaattattg acattaaaga agatttattg cacaataaag attgtgctaa
    40501 tttaatccct aagctagaaa atatagaaga tgtatgtagg gagatgataa aatgatattt
    40561 gaaggattgt ctgataaact acaaggggca tttagtaagt taaaatctaa aggaaaactt
    40621 acagaagtag atgtaaaaaa tgctatgaga gaagttaaac ttgctcttct tgaggcagat
    40681 gttaacttta aagtagttaa agatttcata aaaaaagttc aagagagatg tgttgggcaa
    40741 gaagttatgc aaagcttaac tccagctcag catgtaatca aaattgtaaa tgaagagctt
    40801 acaagtttaa tgggagatgt acaaagtaaa gtaatgattt cctcaaagcc tcctacaatt
    40861 ttaatgatgg ttggattgca aggtgcaggt aagactacta cagcaggaaa acttggagga
    40921 tattttaaaa agcaaggtaa aaaacctcta ttagtagctt gtgatattta tagaccggca
    40981 gctataaagc aacttcaagt tgttggagaa aaattggata tacctgtatt caatatggga
    41041 gataaagaaa atccagtaaa tattgcgaaa gcaggtttaa gtcatgcgat taaaaatgct
    41101 aatgatttag ttattataga tacagctggt agacttcata tagatgaagt acttatggat
    41161 gagttaaagt ctattaaatc agaagttaag ccacatgaga tacttttggt tgtagattct
    41221 atgacaggtc aagatgctgt aaatgttgca gaaagcttca atgaggcact tggtgttgat
    41281 ggagtagtat taactaaatt ggatggagat actagaggtg gtgctgcact ttcaataaga
    41341 gcagttacac aaaagcctat aaaatttatg gggatgggag aaaagctaga tgatatagaa
    41401 cctttccacc cagatagaat ggcatcaaga atattaggta tgggagatgt cttaagttta
    41461 atagaaaaag cacaagaaaa tatagactta gagaaagcta aagaattaga gcaaaaaatt
    41521 aaaaaacaag agcttgattt tgaagatttc ttacaacaaa tggaacaaat acaaaatatg
    41581 ggacctcttg acaagatact tggtatgata cctggtatgg gaaatgtaaa agaccaactt
    41641 ggagatgtag atttgaatgg caaagaaatg aagagaacaa aagccataat tcagtcaatg
    41701 actacatatg agagaagaaa cccaggagta ttaaatgctt caagaaagaa aagaatagct
    41761 aaaggcagtg gaactagtgt acaagatgta aatagactta taaaacaact taatgaaatg
    41821 aaaaaaatga tgaagatgtt tgctggttca caaaagagta tgaagaaaag gggcggctta
    41881 ggcggtttac ctttttttaa ataaaatata aaaaagtaaa aattattcgg aggtgactgt
    41941 aatggcagtt aaaataagat taaaaagaat gggagctaac aaaaaacctt tctacagaat
    42001 agtagtagct gattcaagag ctccaagaga tggaaaattt atagaagaaa taggatacta
    42061 taatccaatt tctgaaccta aacaagtaag aataaatgat gaaaaagcta taaaatggtt
    42121 agctactggt gctcagccaa cagaagtagt taaaaaatta cttgtaaaaa acggagtaat
    42181 agaaaaattc gaagcttcta aacaagcaaa ataatttttt cttggcaatt agtttaagta
    42241 agggctcatt gctaaggtta ctttaggaga tgaaatatat gaaagagcta gttgtagata
    42301 tagctaaggc tctagttgat aatcctgact cagttgttgt tgaggaattt gaagataatg
    42361 atggtatcgt cttaaagctt acagttgctc aagaggatat gggtaaggtt attgggaagc
    42421 agggaagaat agctaaagct ataagaactg tcgtaagatc tgttgcaaat agagaaaata
    42481 taaaagtttc tcttgagata gtataaaata ggaggattag gtataatgcc tagtcctttt
    42541 tatataaatg cgtagtttaa gattttatga tgatatgacc acataagatt aaatttttta
    42601 agaaggtgat aacatgaaag aaaaattaac tcattttaag gtaggtcaaa tagtaaatac
    42661 acaaggttta aaaggtgaag taagagttta tccgcttact gatgatatag agaggtttga
    42721 tgaattaaaa gatttctatc tgggaaaaga tttaaataat aaattggctg ttgaaaaagt
    42781 aagatacaaa ggttctatgg ttataatgaa gataaaaggc atagacagca tagagaaagc
    42841 agaaaaacta aaaaataaat ttatgtatgt agctagagaa gatagcagag agcttgaaga
    42901 aggcgaattt tttatagcag atatgattgg aatggaagtt ttaactgtag atggaaaata
    42961 tgtagggata ctagaagatg ttcttcaata ctcagcaaat gatgtctatg tagtaaaagg
    43021 tgaggaagat aaagaattta tgataccagc tataaaaaaa tttgtaccta caatagatat
    43081 tgatgaaaga aaaatgatta tagaccctat taagggaatg atagattagg tggtaatatg
    43141 agatttcata taatgacact ttttccagaa atatttaatt cgtacatgga tgaaagtata
    43201 atgaagagag cagttgaaaa aggtataatt gaggttcata tatataatat aagagatttt
    43261 tctaataata aacataaaaa agtagatgat tatccatttg gaggaggagc ggggatggta
    43321 atgactcctc aacctatata tgacacatat aagcatataa taacaactca taatataaat
    43381 aacccaagtg taatttatct tactccaaaa ggtaaggtat acaatcaatc tatggcaaag
    43441 cagatgtctt taaaagaaga tataatacta ctatgtggtc attatgaagg aatagatgag
    43501 agaatcattg atttaatagt tactgatgaa atttcaattg gagattatgt attaactggg
    43561 ggagagctcc cagcacttat aatgatagat tctatatcga gattaatacc aggtgtatta
    43621 aaccaagaag aatcatttga agaagaatca tttaaagata acttattgga atatcctcat
    43681 tacactagac ctagagattt tgaaggatta aaagtaccag aagtgctttt atcagggaat
    43741 cataagaaga tagatgagtg gagaagagaa gaatctataa ggataaccaa agaaagacga
    43801 tttgatttat ataaaaaatc taatgaaaaa taaaaatcta atgaaaaatt aatatatatg
    43861 tatacaataa agtacctata aatggaatta aaaacataaa agtgcttgta ataactattg
    43921 aagtatagta taatataaaa tgttgaaaat acgggcgttc ctctgtttac actggtcggg
    43981 tagttaagaa cgtctatgat atctaggagg aagaaagatg aatgaaatgc taagagcaat
    44041 tgagcaagaa caattaaaaa atgaagttcc taattttgga cctggggaca cagttaaagt
    44101 acacgttaga attatagaag gaaaaagaga aagaatacaa gtattcgaag gtgtagtatt
    44161 aaagagacaa ggtggaggag caagagaaac tttcacagtt agaaaaatgt ctttcaatgt
    44221 tggtgtagaa agaactttcc cagttcactc tccaaaaata gaaaaaatag aagttactag
    44281 aaaaggtaaa gtaagaagag ctaaactaaa ctacttaaga ggtagagtag gtaaagctgc
    44341 taagataaaa gaagctagaa ataaataatt aaaaacttta cttataaatg gggggctgat
    44401 ttatcagtcc tctttctatt ttaatgaaaa ttacagcaaa taattatact agaaataaat
    44461 agaaatattt gttgaaaata tacattattt atctatgaat ttatagcttt taaaatgaaa
    44521 aataaaattg gtaaatattg cattatattt tgtaacaata ttaaaaataa gagaacagta
    44581 ttatgtaaag tatgacgtta aaaagatgac aatattatag cttgttaaga tagatttttt
    44641 aagtggaatt aggatataat aatataatat taataaggag tgatacatgt gtcaaatgaa
    44701 tacgaagagt atcttatgaa tgacaatcta catataaact ggtatccagg tcatatgaaa
    44761 aaaactaagg agttagtaaa aaataactta aaattgattg atgtagtaat tgaacttttg
    44821 gatgctagaa tcccgtttag tagtaaaaat ccagacatag acaggcttgt aggagataag
    44881 ccaagagttg tcgtacttaa taagagtgat atggcagata gggataaatt gaatcaatgg
    44941 attgaatact ataagaaaat taatatcaaa gctataccag tagatacaat aaaaggcgtt
    45001 ggtataaata agataatcga agaatgtaaa aatgtaacta gagaaaaaat gagttcttta
    45061 aaagacaaag ggagaaaaga aagagctata cgaataatga tagttggagt tccaaacgtt
    45121 ggtaaatcgt ctcttataaa caaattaaca ggtagaaaaa gcactcaaac tggagataag
    45181 ccaggagtaa cgaaagggaa acaatgggtt agattaaagg gaaatcttga acttttagat
    45241 acacctggaa tactttggcc taagtttgaa gaccaagaag ttgcattaaa tttagcattt
    45301 agtagagcta taaaggatga gattttagat actgaaactt tggctttaag acttatagag
    45361 aaacttatga aaatagaacc tgagaagttg aaagccagat ataagttaga ttgtctagga
    45421 gaaactccaa ttgaaactat ggatatgatt ggccataaaa gagggtttat aacaggtaaa
    45481 aaagaactag attatacacg catagccaca actgtattaa atgaatttag agatggaaaa
    45541 ataggaaata taacattgga agttccagaa aacgttaaaa gatagatttt aaaacaaaat
    45601 caaaaattta atgttaaaaa tttaaaaaag ccttttagca aaggcttttt tatttttttg
    45661 aaatatagac aaatatctcc atataaaagt ataaattagg ttagaaaacc tttaaaaata
    45721 ttaatttaag acaaatatac ctaatatttt gaaaattaaa atgagtgtga ttatttaaaa
    45781 ttttagcata ttgacttgct tgtttcgtat aatatataat aagcacaaat aaatacaata
    45841 tattaaaaat ttaatttatt taattttatt aatttaataa taagttctta ttgtttaatt
    45901 caacttactt atgcaagcgt aaacaatcga gacattttat taatttaata aggttaaaaa
    45961 gggggatttt ataatgggta agaccaagga tgttatagta tttggatttg cgttatttgc
    46021 aatgttcttt ggagcaggta acttaatatt tccaccttac ttgggaataa ttacaggtcc
    46081 agaatggtta attgccttct taggatttac gtttgctgat gctggattgg cacttctagc
    46141 agtaatggct acagctaaat tcgatggaaa cgtagttgaa atgtttaaaa gatgtggtat
    46201 gaagttagga attcttatag gttgtgcaga tattttatgt ataggaccat tcttagctat
    46261 accaagaaca ggtgcaacaa cttatgaaat gggtataatg cctttgtttg gaacttcaat
    46321 tccagtgtta ttattctgta tacttttttt tgcgatttca tatgtactaa caataagacc
    46381 ttctaaggtc gtagatatag ttggacagtt tttaactcca gctcttctaa tagctttagc
    46441 atttataatt ataaaaggta ttatatcacc tcttggagat atagtagata aacctatgat
    46501 acctaatgta tttgcagaag gtataggtca aggatatcag acaatggatg cttttgcagc
    46561 aatagcactt gcatcagtgc taatagtatc tttaaatgat aaaggatatt ctactattag
    46621 tgacaagttg aaaatgattg gtaaggcggg tgttcttgct tgtggaggat tagctctagt
    46681 ttatggagga ttatgtttcc ttggggcaac tgtatcaaca atgtatggaa cagatgcagt
    46741 acaatcacaa gtaatagtaa atataactga aggattgctt ggaaatgttg ggaaagcgat
    46801 tttagcagta gtagtatcat tagcatgttt aactacatct ataggtctta catctgccac
    46861 aggtcaatat ttctctagac ttacaaaagg taaattgagt tatgaaaaaa tagtattagc
    46921 tgtatctgta ttcagtgcag tagtagcatc ttttggtgtt ggaactataa taaagatagc
    46981 atctcctata ctaagtatag tttatccacc atcaattgtt ttaataattt tagctttctt
    47041 caatgaaaaa attaagaatg ataatgtata caaaggagca gtatatatgt cattgcttgt
    47101 aagtatacta acagttatat ctagttatgg agtagctgtt ccagtagtaa attctttacc
    47161 tcttaattca ttaggattta actgggtggt gccagttata atagctggaa taattggtaa
    47221 ttttatacca tcaaagagtc aatctaatac acttggaaca aactaagttt tgtttaatta
    47281 aaatataatc aattgtaaat aaatgagtta actaaaagta aaaggagtta tttgtacaaa
    47341 ta
//
LOCUS       DAEOTL010000023        46917 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEOTL010000023 DAEOTL010000000
VERSION     DAEOTL010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.023"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            79..1290
                     /locus_tag="KRH82_001602"
     CDS             79..1290
                     /locus_tag="KRH82_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBG8654883.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            1482..1742
                     /locus_tag="KRH82_001603"
     CDS             1482..1742
                     /locus_tag="KRH82_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBG8654884.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            2096..3808
                     /gene="ptsP"
                     /locus_tag="KRH82_001604"
     CDS             2096..3808
                     /gene="ptsP"
                     /locus_tag="KRH82_001604"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBG8654885.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLEN
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            complement(4600..5265)
                     /locus_tag="KRH82_001605"
     CDS             complement(4600..5265)
                     /locus_tag="KRH82_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654886.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
     gene            5609..7039
                     /locus_tag="KRH82_001606"
     CDS             5609..7039
                     /locus_tag="KRH82_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBG8654887.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            7407..7985
                     /locus_tag="KRH82_001607"
     CDS             7407..7985
                     /locus_tag="KRH82_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBG8654888.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            8015..8161
                     /locus_tag="KRH82_001608"
     CDS             8015..8161
                     /locus_tag="KRH82_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBG8654889.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            8466..9845
                     /gene="scfB"
                     /locus_tag="KRH82_001609"
     CDS             8466..9845
                     /gene="scfB"
                     /locus_tag="KRH82_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBG8654890.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            9874..10371
                     /locus_tag="KRH82_001610"
     CDS             9874..10371
                     /locus_tag="KRH82_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBG8654891.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            10669..12333
                     /locus_tag="KRH82_001611"
     CDS             10669..12333
                     /locus_tag="KRH82_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBG8654892.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            12346..14796
                     /gene="recJ"
                     /locus_tag="KRH82_001612"
     CDS             12346..14796
                     /gene="recJ"
                     /locus_tag="KRH82_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBG8654893.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            14809..15321
                     /locus_tag="KRH82_001613"
     CDS             14809..15321
                     /locus_tag="KRH82_001613"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBG8654894.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            15395..17602
                     /locus_tag="KRH82_001614"
     CDS             15395..17602
                     /locus_tag="KRH82_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBG8654895.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            17627..18076
                     /locus_tag="KRH82_001615"
     CDS             17627..18076
                     /locus_tag="KRH82_001615"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBG8654896.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            18091..18705
                     /locus_tag="KRH82_001616"
     CDS             18091..18705
                     /locus_tag="KRH82_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8654897.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            18796..20352
                     /locus_tag="KRH82_001617"
     CDS             18796..20352
                     /locus_tag="KRH82_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBG8654898.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIKNMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFLVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKETKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            20342..21604
                     /locus_tag="KRH82_001618"
     CDS             20342..21604
                     /locus_tag="KRH82_001618"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBG8654899.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            21678..23465
                     /gene="aspS"
                     /locus_tag="KRH82_001619"
     CDS             21678..23465
                     /gene="aspS"
                     /locus_tag="KRH82_001619"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBG8654900.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            23924..25156
                     /locus_tag="KRH82_001620"
     CDS             23924..25156
                     /locus_tag="KRH82_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBG8654901.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            25170..25976
                     /locus_tag="KRH82_001621"
     CDS             25170..25976
                     /locus_tag="KRH82_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBG8654902.1"
                     /translation="MGRKVKIGIIQQHSVLGDVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(26088..26957)
                     /locus_tag="KRH82_001622"
     CDS             complement(26088..26957)
                     /locus_tag="KRH82_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8654903.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            27329..28756
                     /locus_tag="KRH82_001623"
     CDS             27329..28756
                     /locus_tag="KRH82_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBG8654904.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNDLNSQTEKELK
                     RLGVKKVYIIGLSSSISNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(28832..29101)
                     /locus_tag="KRH82_001624"
     CDS             complement(28832..29101)
                     /locus_tag="KRH82_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654905.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(29104..30546)
                     /gene="nhaC"
                     /locus_tag="KRH82_001625"
     CDS             complement(29104..30546)
                     /gene="nhaC"
                     /locus_tag="KRH82_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBG8654906.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFVVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(30571..31737)
                     /locus_tag="KRH82_001626"
     CDS             complement(30571..31737)
                     /locus_tag="KRH82_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8654907.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(31962..34082)
                     /locus_tag="KRH82_001627"
     CDS             complement(31962..34082)
                     /locus_tag="KRH82_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8654908.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMEYDYNFKKSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILIGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            34310..34711
                     /locus_tag="KRH82_001628"
     CDS             34310..34711
                     /locus_tag="KRH82_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654909.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            34754..35047
                     /locus_tag="KRH82_001629"
     CDS             34754..35047
                     /locus_tag="KRH82_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBG8654910.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            35062..35502
                     /locus_tag="KRH82_001630"
     CDS             35062..35502
                     /locus_tag="KRH82_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBG8654911.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(35594..36067)
                     /locus_tag="KRH82_001631"
     CDS             complement(35594..36067)
                     /locus_tag="KRH82_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBG8654912.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(36067..36855)
                     /locus_tag="KRH82_001632"
     CDS             complement(36067..36855)
                     /locus_tag="KRH82_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBG8654913.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            37183..38427
                     /locus_tag="KRH82_001633"
     CDS             37183..38427
                     /locus_tag="KRH82_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBG8654914.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            38750..39847
                     /locus_tag="KRH82_001634"
     CDS             38750..39847
                     /locus_tag="KRH82_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBG8654915.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            39838..40536
                     /locus_tag="KRH82_001635"
     CDS             39838..40536
                     /locus_tag="KRH82_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8654916.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            40539..41603
                     /locus_tag="KRH82_001636"
     CDS             40539..41603
                     /locus_tag="KRH82_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBG8654917.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            41786..42490
                     /locus_tag="KRH82_001637"
     CDS             41786..42490
                     /locus_tag="KRH82_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8654918.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            42483..43805
                     /locus_tag="KRH82_001638"
     CDS             42483..43805
                     /locus_tag="KRH82_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8654919.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            43971..45344
                     /locus_tag="KRH82_001639"
     CDS             43971..45344
                     /locus_tag="KRH82_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654920.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISASAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(45716..46654)
                     /gene="pdaA"
                     /locus_tag="KRH82_001640"
     CDS             complement(45716..46654)
                     /gene="pdaA"
                     /locus_tag="KRH82_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBG8654921.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        18164 a         5252 c         7966 g        15535 t
ORIGIN      
        1 taactaaaaa tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt
       61 gatatagtag gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc
      121 taccaaatag gtgcatataa agctttaaga gagcttggta tagagtttca aggagtaact
      181 ggcacatcaa ttggtgcttt aaatggagca tatataattc aaaatgatat tgaagtaatg
      241 gaagatattt ggttaaatta tgactatact cattttatga atattgatag agaaacctat
      301 gagaggttta aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata
      361 aataaagcta gaaaaaatga aggtatagat ataagcccat taagacaact aatggagaca
      421 acattaaatg aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg
      481 tgggataaaa aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg
      541 attgattatt taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat
      601 aagttgtatc ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa
      661 ggttatgaag atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta
      721 aatcgacatc aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct
      781 cttaataaag atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg
      841 aaagcatatg aaagatgcac tggaattaag tattattttg atgtagagta taaatataat
      901 gaagaatatt gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt
      961 aatttattga atataaaaag agatgcttca cttagaactg ttatggaaag tgtaatacca
     1021 aagcttggtg aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt
     1081 atatatgaaa agaaacttga agaaaataat ataaacagga taaaattata tgattttaac
     1141 aaggttatag atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt
     1201 gaagttagac ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt
     1261 attataaaag acataaaaaa tcaaagttaa ataaaaaaca aaaaaaattt gtaattatac
     1321 tcgaaaaaag tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg
     1381 accataggac aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt
     1441 aaaaaatata aaatgtaaag tttataggag gatttaaaaa aatggaaaaa gtagttagta
     1501 tcaaaaatgc aagtggatta catgctagac cagcaggaat gtttgttaag aaggcagctg
     1561 aatttaaatc aacagtagag gttgtagcaa aagacaaaac tgtaaatgca aaatcaataa
     1621 tgggaataat gagtttaggt ttagctcaag gagaagaatt aaagttagtt gtaaatggag
     1681 aagatgaaga agtagcttta gctgcaatgg ttgaattagt tgaaagtgga tttggagaat
     1741 agatataata attttttaaa aatttgatat ttagaatcta atattactta aagtaaagta
     1801 acagagaagt attaaacata tacagaccaa catttgtaga tatttaattt ctttgttact
     1861 ttcatgttta tttaatcaga agattaagac tattgttaat tgggtataaa aatataaata
     1921 ttttagaaaa tgaaataaga tatttttaat cataaattca gagtaaaaat acagtaacaa
     1981 atagtttata aaattttata aaaaattata agtaaataaa actataaaaa tgtaaattat
     2041 ttataaaatt ttatagagtt tatgtgctag atgatatttt ttaggaggta gggttatggc
     2101 ttacaaagga ataggtgctt ctcctggtgt tgctttaggg aaagcgttag tagttgaaca
     2161 tagtgaatta gtaattgaaa aaaaatctat agataatgtt gaagctgaaa ttgctaaatt
     2221 agaaaatgca gttgcagttt ctaaagaaga attagtaaaa gttaaggaaa aggcttctga
     2281 agaattagga gcagaggaag cagaaatatt tgaagcacat ttattagtct tagaagaccc
     2341 agaattaatt ggttctgcaa tagataaaat caaaactgaa agtgtaaatg cagagtatgc
     2401 tttaaatgaa ataaaagaga tgtttgttag catgtttgag tctatggaca atgagtacat
     2461 gaaagaaaga gcggcagata taaaagatgt tacaaataga atacttagac atatattagg
     2521 aattaaagtt gttgatttat ctgctttaag cgaagaagtt gtattaatag cacatgattt
     2581 aactccatca gacacagcaa ctatgaataa aaaaatggtt ttaggatttt taactgatat
     2641 aggtggaaga acttctcata ctgctatcat gtctagaact ttagaaatag ctgcaatcgt
     2701 tggattaaat gatataactt caaaagttaa ggatggagat tttgtagttt tcaatggaga
     2761 cacaggtgaa gtaatcgtga atcctgatga agagactata aataaatata ctgaattaaa
     2821 agctaagtat gaagatgaga gaaaagcatt acagctatta aaaggaaaac catctgtaac
     2881 tttagatgga aaacatgtag aattagctgg taacatagga acacctaacg atatagaagg
     2941 tctaataaag aatgatgctg aaggtgttgg tctttataga acagaatttt tatacatgga
     3001 tagagattct ttcccaacag aagaaataca atatgaagca tacaaagctg tattagaagg
     3061 aatggatgga aagcctatag ttataagaac attggatata ggtggagata aagaattaag
     3121 ttatttaagt atggaacctg aaatgaatcc attcttaggt tacagagcaa taagactttg
     3181 cctagataga aaagatatat ttaagactca attgagagct ttatatagag ctagtgttca
     3241 tggaagatta agaatcatgt tcccaatgat ttcatcttta gaagagttgt tacaagctaa
     3301 agaagttgta aaagaagttt tagcagaact tgattctgaa ggtgtggctt atgctaaaga
     3361 tgtagaaatt ggtatgatga tagaagttcc atctgctgct gtgatatctg atgtattggc
     3421 taaacacgta gatttcttct ctataggaac taatgattta attcaataca cttgtgcagt
     3481 tgatagaatg aatcaaaaga taagttatct ttacaatcaa tttaatccag ctgttttaag
     3541 acttataaag actgttatag acaatgcaca caaagaagga aaatgggcag gtatgtgtgg
     3601 agaatctgct ggagaccaaa aaatgatacc aatactttta ggtatgggat tagacgagtt
     3661 ctctatgtct ccaatatcaa tacttcctgc tagaaagtta ataacttcag ttaaagagtc
     3721 agatatgaaa aaattagctg atgatgtact taatatgggt actgctgaag aaataaaaag
     3781 ctatatagaa aagactttta atatataatt aatgttatat agttactaaa attcattttt
     3841 ctaaataaca aaattatatt ttacgaatta aaaagaagat gtttcaaaat aaaaatttga
     3901 agcatctctt ttttataaaa gattactaag aattacttaa tctttgtaat agtcattttg
     3961 tgaaaaagca aaactgcatt gtgactatag tatatatgga tgttattatc aataaaagta
     4021 ctattaaaat gaagattcat tctcaaatgg tatcaaaagt agttgtgatg gagtaagata
     4081 atattttgtg atttaatagt aaaaattaaa aaaatatggt attgaaaaat aattaaaagt
     4141 atttaataat agaattaggg aagaataagt ttataagtaa aaataattga ttagtagtta
     4201 ataaaataaa tgtgatatcc aaataaatcc taaatctaat ttgagtttta atatagatag
     4261 tctaaagttt gattattaaa gatttaattg taagttgtta cagttgatga tattgattag
     4321 agattaaagt ttagagtaga aagttacctt aaatttaaaa atgcaagata acccaatcta
     4381 aaaattataa tcactcgata ggtttaagga tttatttgtt tattataaat aggagggtgt
     4441 ctcaaaatga actttttagt ttatgaggca ctctctttta tatagaatta aatatatttt
     4501 attatttcaa caatgaaaaa gaagcttatc tctattttga gacagcctct ttgtatacta
     4561 ttattaattt aatcaataac ataatttaaa attatattat tagttaagat ttcctgcttt
     4621 attagtaaat aattctttaa tagcattgtt tctggaaact aaatcgttat cagagttgtt
     4681 tgtttttttc ataatcactg aataacgttt tttatttata aaaaatatta aaatcttatc
     4741 atcatcaaaa ttgtattctt tatatctgtc aatagactca taacctagat ttagaatgtt
     4801 tttgtctttt atactatcta catctaaaat atatgatggg tcagccttta gtaatatatt
     4861 aattaaacat ttttcttcac cagcacagaa taactccatc ttacttgata tagatttaga
     4921 ttgctctgaa gttatttttg caggaataag gttgtcatta tcatctctta gaagataacc
     4981 atgtgtgtct tgttgatata ctaaattaac ctttttctta ggaacactaa tcattttatc
     5041 taaatgtaca taatgatgat tttcaacaaa accttcattt aatatttcaa caaagttatt
     5101 aattttacct aggcaaaaag attctataga ttctttacag aatttatttg taaatggtat
     5161 tatgtttacg ttttcctcgt ctgtattcca tgctatagca taatccaacg aatatacttc
     5221 ttcctctata tctgcaaaat tatattgtac tatgtttcct ttcaaaatta ctcgacctcc
     5281 atcttataat atatttaata tactttataa aacttatatt atatttaaat aatatcataa
     5341 attggataaa tatgatatag taaataagaa aaaatttgaa aaaaatcact ataaatgagt
     5401 aataaatata aatagtgtat actaatggga tggaaaatgt ccactattaa ctttattacc
     5461 ccacatatat aagataaaat tattaatata aaatataatc tatcgacaat gaatagactt
     5521 ttaaataaac ttaatataaa attaattaaa taagtgctta aaaacgattt actttaatga
     5581 tagaatcata ttaaaggagg ataattttat ggatataaag aataaaatta aatctatatt
     5641 tttaccagaa aaaaatgact atttagatga tgaagaattt gagtatgata tagaaaataa
     5701 tgaagaagat ttaaaggaag ataacaaagt acatttaaat gatttaagca gagtaaaata
     5761 tgattacaga gagttaaaag acatagaaaa ccaaacagaa gagatgtgtc tgctagcagt
     5821 aaagcaggat ggtactataa ttgagtttgt aaaggacaag acttataaag tatgtatgga
     5881 agcagtaaaa cagacatata aatctcttaa gtatataaca aatcaaaatg aggatatttg
     5941 tatagaagca gtaaaacaga actacagagc tttgtactac ataaataata agacagaaaa
     6001 tgtactaatt gaggctataa aaaatgcatc aacttatgat gtcatggaag tatttaaatt
     6061 tgtggaagag caaacagaag atgtatgtct agcatttata gaaagggcat ctaaaaatga
     6121 tgttgcagag atattaaaag gaataaaaga gcaaactcca gccatatgtt tagaagctgt
     6181 aaaaaaagat ggaaaatctt tagcttatgt aaaggaacaa agtaatagta tatgtttaga
     6241 agctgtaaaa gaaaactaca gtgcactatc ttgtgtaaaa gagcaaactg aagaaatatg
     6301 catagaagca gtaaaacaga atgactttgc attgtattat gtaaatgaac agacagaaaa
     6361 aatatgtatg gaagcagtaa aaagaagtta tatggctcta cagtatgtaa ataagcaaac
     6421 agaagagatt tgtttggaag cagtaagaat tgatggaaga gcattacagt acgtaaaaga
     6481 gcaaacagaa gaaatttgct tggagtcagt tagacaaaat ggaaaagtac tgcaatatgt
     6541 aaaaaaacag actgaaaata tatgtataga agcagtaaga ggttcatttg aagaacttga
     6601 aataaaagaa atattaagtt atgtaaagat accaacagaa agaatatttg tagaagcagt
     6661 aaagcaaaat ggaaaaattc ttaaatatgt agaaaatcag acagaattaa tatgtttaga
     6721 ggcagtaaga gaaaactata atgctttagc ttatgtaaag gaacaaacag aaaagatttg
     6781 tttagaagca gttaatcaaa gttatgaagc gcttaaatat gtgaaagaac aaacagaaga
     6841 agtttgtcta aaagcagtaa aacaagatta tagaatgttg aaatatgtaa ataatcaaac
     6901 agaaaaaata tgtttagaag cagtaaagca aaattataga gctttagaat ttgttgataa
     6961 tcaaacagaa aaagtttgtc ttgaagcagt aaaacagaat agaaaagcac tacagtatgt
     7021 aaaacaaaaa caaagttaaa aggctaaaat atatagaaaa tatatgcaaa taaataaaat
     7081 ttgatatttt gtaataaata aaatgggtat ctcaaaatga actttttagt ttgtgagata
     7141 ctctttttat atgaaataaa atatattttt agccttttaa caatagggaa aaggtttatt
     7201 tctattttga cataggcttt ttatgcatat aaagcttgat aaaattgttt tattataatt
     7261 gttttgttat atgaataata agaagaaaat tatataggtc tttttttgac cagttttaca
     7321 tttttaacaa ctagttttgt aaagtatatt gaattttctc aaaaaagaat gtactctata
     7381 tatgtaaaat ttttttggag gtaaaaatgt ttaaaagata tgctgaaaaa atgacatctg
     7441 ttttaatttg taataatatg atagataata atgaatctaa agtctattct tatggatttg
     7501 aaatattaat agctttcata gttaatataa ccaccatgct gtttataggt tttttatttg
     7561 gtaaatttac atatgtatta ttttttttaa tgtgttattg tccaataaga caattttcag
     7621 gagggtatca tgcagacaat tattttagat gcttattaac ctttattttt ataattttat
     7681 ctacaatctt aattatagaa aatataaata tagacttatt taaaaatatt attatgatta
     7741 ttgcaagtgt tagttgggtt ggaatttgtg ttctgtgccc aatagaacat aggagtaacc
     7801 ctataagtga tagggaaaag ttggtttata agaaaactgc tatatttata tctacagtag
     7861 tgttattgat aacaatttta agtctttctt tgagtatatt tgtagattat ttcacatata
     7921 gcgcatttgc catgttttgg atttttgtga tgttagtatt aggtaagtta aaagctaaag
     7981 tataagtaaa atatgtatga gggagagtta agttatgaaa aagtttattg taagatttat
     8041 gaagtttgct agctcattgg cacttagcac tgctattttg tcagctaata gtacctgtcc
     8101 ttggattatt catcagccta aagtacccaa agaaatcagc aatctaaaga agacaaatta
     8161 aatacaagca cttatttata caaaattatc aggaaaaaag aaattattat attttaataa
     8221 gattaaaaca atataaaatc agatacaaaa tttattttat ttattttata ggagcctaat
     8281 acctatttgg taatatatta gtgcgccaat ttagggggat atagtgtatt taatgaaatg
     8341 acttacggag agtaagtcat ttttgtattg tatgtatttt atgtaaactt atgatataat
     8401 gaagggtaaa gtttaattaa aataataaaa aactttagta tagatagtaa tttaggaggt
     8461 agggtatgag tatgatacat aaattttcta tgaatggata taatatcgtt ttagatgtga
     8521 atggtggagc tgttcatgtg ttagatgatg ttgcatacga tttgttagat ttttataaag
     8581 aaaaaagtaa agaagaaata ttagagatat taaaatcaaa atatcaagaa gaaaaaataa
     8641 atgaagcata tgaagaaata ttaaatttgg aaaaagaggg tcttttatat acagaagata
     8701 catatcaata tcatccaagc tttgtacata gagagcctgt agtaaaagct ttatgtttaa
     8761 atgtagctca tgattgtaac ttaaaatgta aatactgttt tgcagctcaa ggtgattttg
     8821 gaggagaaaa agaacttatg agttttgaag ttggtaaggc agcaattgac tatttgattg
     8881 ctaattcagg aagtagaaag aacctagaga tagatttctt tggtggagag cctttgatga
     8941 actttgaagt tgtaaaacaa ctggttgact atggaagaag tgtagaaaaa gattataata
     9001 aaaatataag atttacaata actacaaatg gtgtactgct aaatgatgag attatagatt
     9061 atataaatga aaatatgcat aatgtagttt taagtttaga tggaagaaaa gaagttaatg
     9121 ataatatgag accaacttta aatgataaag gaagttatga tattacatta ccacgattta
     9181 agaaacttgt ggaaaaaaga gcaaaagata agtattatta tataagaggt acttttacaa
     9241 gagataattt agatttttca aaagatgtta tgcattttgc agatttagga tttaaattaa
     9301 cctctgtaga gccagtcgtt ggagatgaga gtaatccata tgcacttaga gaagaagatt
     9361 tacctaagat atttgaagag tacgaaaaat ttgctgtaga gtatgcagat agacaattac
     9421 aaggagatgg atttaaattt ttccatttta tgatagacct aaatcaaggt ccatgtgtaa
     9481 taaagagaat aactggatgt ggagctggaa atgagtatct ttctgtaact ccaaatggag
     9541 atatctatcc atgtcatcaa tttgttggaa atgaagaatt taaaatggca aatatatttg
     9601 atgaagaaat agtacttcca gaaaatttaa aaaatatgtt tagagaagct catgtatata
     9661 ctaaagaaga gtgtaaacaa tgttggaata agttttactg ttcaggtgga tgtcatgcaa
     9721 atgcgataaa ctttaataat gacatatcaa aaccatatga attaggatgt gaaatgcaaa
     9781 gaaaacgtac agagtgctct ataatgatac aagctaagtt aatgttagaa ggagcaacca
     9841 actaaattta tattttaaag gagttgttta tatatgatta gagattattt agaagataaa
     9901 cctttaattg acgaaagtgt atttgtggca aaatcagcag atgtaattgg aaatgttaaa
     9961 ataggcaaag attcaagtat atggtacaat gcagtagtta ggggtgatga aggaccaata
    10021 actattggag aaaacactaa tatacaagat tgttctatag tgcatggaga tacagaaact
    10081 ataattggta acaatgtaac agttgggcat aggtctatag ttcatggttg taaaattagt
    10141 gataatgtgt taattggtat gggttcaata atattggata atgctgaaat aggagaatat
    10201 actctgatag gagcaggtac actaattaca tctaataaga agtttccacc aggtgttttg
    10261 ataatgggtt ctcctggtaa ggttgttaga gagcttacag aagaagataa aaaatatatt
    10321 gatgaatctt atgaatggta tttagaggca gcacaaaatc aaaaatatta gtttaaagag
    10381 tggttgtttc aaaacatatt taaatctgtt ttgaggcaac cactaattta ttttattaga
    10441 ttttgttgat attttagttt tcaaaaagta tttgattaaa ccagatataa aatgtcaaaa
    10501 ataaaaatta actgagttaa ataattttaa taaaattggt agtatatgtg ataaaattaa
    10561 atattaaaga ggatatagga tattagaata tcaattggtg aaataatgtc atatacgata
    10621 aattaaggtg taagtttttg ggtataccta tcttaggagt gaaaagattt gagaataagt
    10681 tatagaaatt taaagcgata tagagaaatt ggatatgttt taataaagta tggttttagt
    10741 tttattgtag aaagactaaa tatagaagga attgcctata aaataccact atttgaccca
    10801 ccagaagaaa taaaaaatat gacaactggt gagagaatga aaagagtttt agaagaacta
    10861 ggacctacat atataaaaat aggacagata ttgagtacaa gaaaagactt gttagaccag
    10921 gatataattg atgaaatatc aaaactcaga gatgatgtag agaaatttga ttcaaatata
    10981 gctattgata tatttaaaga agaagtgggt ttaagtatag aagaaatatt cttagaattt
    11041 aaagaagaac caatagcagc agcttcaatt ggtcaagttt atgaaggtgt acttaaaacg
    11101 ggagaagaag taatcgtaaa aattcaaaga ccaaatatag agaaaataat aaaatctgat
    11161 ttagagattc ttagaactat tgcaaatact ttaaaagatt taaaaaaaga ttttaattta
    11221 gatttagtac agatgattga agaatttcaa actcaattaa tgagggaact tgattataca
    11281 tttgaagcta taaatgcaac taaattctct aggatattta aaaatagtga tgaagtatat
    11341 atacctaaag tatattcaga atataatact aagaaaattt tagtaatgga gaaagttaat
    11401 ggtacaaagt taagtgatgt agaaaaaata aggagactag gttataacac aaaaactatt
    11461 gttgaaatag gcgttaggtc attttttaca caggtattat ctcatggatt ttttcatgca
    11521 gacccacatc caggtaatat attcgtagtt gctaaaaata agatagcata tatagatttt
    11581 ggaatgattg gaattattga taataaaact ttaaaccaat taaatgaaat tgcattagca
    11641 ggtgtagaaa agaatgttga caagataata tatctattga tagaaatgga tgcattaaat
    11701 ggagaggctg atattaaggg acttagacag gatttacttt atctaataca ttattactat
    11761 gatatttcta tagaaaaaat aaatgtaaca gatatattaa atgaactatt taggtttttt
    11821 agacagtata aaatagtcat gcctgcacaa tttgtaactc ttgcaaagac agttataaca
    11881 ttagaaggaa caagtagaac tttaaacaca gatttttctt ttggttctat gggaaaagag
    11941 tttatgaaac atcattataa gagtaaattt aaccctaaaa atgttgtttt aagttcaaga
    12001 caaaatgtag aagaaatatt actggacata aaaactattc caaagcaatt aaaagcaatt
    12061 ttaaaaaata tagaaagaaa taatataaaa atgcaaattg aagatgttaa aatgacgagg
    12121 ttagaaaatt gtataataga gctaacatct caaatatctt tgagtttagt gttggcatct
    12181 attatagtag gttcttctct tataattgca tctccaaata tagaaaataa tatatggata
    12241 aaatttactg caatagcggg tttctttata tcctttataa taggcctttg cttagttata
    12301 agaagtatta ggtcaaaata caaaaaagat tagggggaat taaatttgaa aaaatggata
    12361 ttgaagtata aaggtaagat agaggaaagt gaatttagca aaaaacttaa tatttccccg
    12421 gaaatctgcc aaattttaaa aaatagaggg atatgtactg aaaaagattc agaaatattt
    12481 atgaatccat ctttagatta tttaagagac ccttttttaa tgaaagatat gcaaaaagct
    12541 gttgatagaa taaagttagc agttgagaag aacgaaaaaa tttggattta cggagattat
    12601 gatgttgatg gtgtatcatc tacatctatc ttgtgcttat attttaagag tataggttac
    12661 aatgttgatt actatattcc taatagatta gaagaagggt atggtataaa tgaagatgct
    12721 attaagctta taagctctag gggatgtgac ttgattataa gtgttgactg tggaattaca
    12781 tcagtgtctg aggtcaatac agcgaatgat ttgggcatag atgttataat tacagaccat
    12841 catgaatgtc aaagtgaaat tccatcagcc tttgcagtaa taaatccaaa acaagaagat
    12901 tgtaattatc catttgattc actatgtgga tgtggtgtag catttaaaat gattcaagcc
    12961 ttgactccaa aagaagaatt taaaactagt atgtataatt atttggaaat agtaacacta
    13021 gcaactattt gtgatattgt tccacttata gatgaaaata gaataattgt aaaaaatggt
    13081 ttaaaatcaa tgaaagaagg caaaaatatt ggattaaggg agcttataaa agtttgtggt
    13141 gtagaaagtg ataagatagg ttcttctcat ataggttttg caataggtcc taggataaat
    13201 gcttcaggtc gattgggata ttcttactta ggagtagagc tatttactac tcaatcacaa
    13261 gaagaggcag tagaaatagc tagtatattg gaagaaaaaa ataatgaaag acagatgata
    13321 gaagctaaga tgtatcatga agctgaagaa atgctaaagt ctaatagcag atacaatgat
    13381 gacaaggtgt tggttttagc taaagagggt tggcaacatg gaataatagg aattgtagca
    13441 tcaaagttaa ctgaaaaata ctacaaacca acaattcttt taggtataga aaatggggag
    13501 gctactggtt cagcgaggtc aataaaagga tttaatatat ttgaagctct cataaagtgc
    13561 aaagacttga tgactaagtt tggtggtcat gaacaagcag cagggttatc cttggattca
    13621 gacaatgtag aaattttagc aaatgaaata aataaatttg cagattataa tttaactgaa
    13681 gatgatatga tagagaatgt aaatgtcgag tttgaattac aagaaaatgt aataaattta
    13741 aatcttgtag aagaattaca taagttagaa ccctttggat taaataatcc taatcctaga
    13801 tttatagtta gaaattatat tttaaaagat ttgaaagtta taggtaagaa tcaacaacat
    13861 ctgaaattaa gcatagaaaa agagaaaagc tatgaatgta taggatttaa tatgagtcat
    13921 ttaaaatcaa tgtataaagt aggagacaag gtagatgtac tattccaatt agatgaaaat
    13981 aactatatgg gaaataggaa agtacaattt ttacttaaag atatacgatt ggctcgacct
    14041 aaaagtgcaa gtaatgacaa actttcattg aaattaatgt caaaaataat accaaaagat
    14101 actcaaagcc tgtataatat atctgtgtct gattttgaat tatttgatgg aaatacagat
    14161 ataaatatat ttgattattt tgaaaaagat acactaataa tatctaattc tataaatgga
    14221 ttttatagag caatgtcaga tatatcactt atagatttgg attttaacat aaattacaat
    14281 attattgaag atgttagcaa aaatactgat aaattagagc ttatattttc tcctaatatt
    14341 gataaaatag acttaaaaag atataataat attattcttt atgattattt atacaataaa
    14401 ggcgaatatt cgtatatata tgagaataaa agagaagaaa gtgaaattat aaaatattat
    14461 aataaaacag acctattata tttaaagaat gtagttagta atatagttcc atcaagagat
    14521 gaatttataa caatttataa acaagcactc ataaaaaaag aaattgattt ggatatggta
    14581 aatataaggg aaacttttaa tgtaattcca ttaaagtttt ttacgatatt aaatgtattt
    14641 agagaattaa atttacttga ctttaattta aattatgaaa aaaattctgt actcataaga
    14701 atattgccaa aaccacagaa aaaattagac ttaaatgaga gtttaatact caataatcta
    14761 aaaaatttag aaaaacaata caatagcagt tattaggagg cgtttcccat ggatttaaaa
    14821 aactttataa ggaatattga tgatttccca aagccaggca tagattttaa agatgtgaca
    14881 actctattta aagatggaga tgcatttaaa tatgcagtgg attctatagt tgaagaattg
    14941 aaagataaag atgtagattt agtaatagga ccagaagcaa gaggattttt gatgggtaca
    15001 cctgtagcat atgctttagg agtaggattt gttccaatta gaaaacctgg aaagttacca
    15061 ggtgaagttg agagttatga gtatggatta gagtatggta cagatacttt agagatacat
    15121 aaggatgcaa ttaaaaaggg tcaaaaagta gcaatagtag atgatttatt ggctactggt
    15181 ggaactatgg aagccgctgc caagcttgta gaaaaattag gtggagaagt agtttctatg
    15241 caatttttga ttgagctaaa attcttaaat gggagagaaa agttgtctaa ctatgatgtt
    15301 aattctctta taaaatacta gtacttttat aatagttggt ataacaccaa ctattttcat
    15361 atatattaaa attttataca aaataggtgg ttatatgcat gataaagaat tacaagaaat
    15421 aattgaaaaa ataaaagttt atgcacctaa tgcaaatttt gaaatggttg aaaaagccta
    15481 taatcttgca aaaaaagcgc atgaaggaca atatagaaaa tctggggaac catactttat
    15541 tcatccatta gcagttgcaa atattttaat agagatggag ttagatattg aaactataac
    15601 agcaggttta cttcatgatg ttgtagaaga tacagaatat acctatgaag acataaaaaa
    15661 agaatttggc aaagaagtag cggatttggt tgatggagta actaaacttg gtcaaataaa
    15721 atatcgttcg aaagaagaaa ctcaatctga aaatttaaga aaaatgtttt tggcaatggc
    15781 gaaggatata agggttatac ttataaaact tgctgataga ttgcacaaca tgagaacatt
    15841 aaaatacatg cctccagaaa aagcaaagta taaagcaaaa gagacacttg aaatttatgg
    15901 tggtatagct catagattag gaatttccaa gataaagtgg gaactagaag acagagcatt
    15961 aagatttatg gacccagaag ggtattatga tttagttagt agagtatcaa tgaagagaag
    16021 tcaaagagag gattatattc aaggaattgt tgaacttctt aaagataagt ttaaagattt
    16081 aagtatacca tgtgatgtat atggtagacc aaagcatttt tacagtatat atagaaagat
    16141 gcaaaaaaaa cataagactt ttgaagagat ttttgattta acagcagtaa ggatattggt
    16201 tgataatgta aaggattgct atgcagtact tggtatagtt catacattat ggagacctat
    16261 tccaggaaga tttaaagatt atatagcaat gccaaaaccc aatatgtatc aatcattaca
    16321 caccactgtt gtaggtcctg atggagaacc tttagagata caaataagaa ctcatgagat
    16381 gcataatata gctgaaaatg gtatagcagc ccattggaaa tataaagaag gtatctctag
    16441 caaagagtca aaggttgaag aaaaacttca atggttgaga cagatgatgg agtgggaaaa
    16501 agatttaaaa gacccacaag agtttatgga tgcacttaaa gaagatgtat ttaatagtca
    16561 agtttatgta tttacgccaa aaggagacgt aattgaatta ccagcagaat caacacctat
    16621 agattttgcc tatagggttc atacaaatgt aggtaataaa tgtgtaggag ctaaaattga
    16681 tggaagaata gttcctattg attataagct tcaaaatggt aatattgtcg aggtacttac
    16741 atcatctaat tctaatggac caagtaggga ttggcttaat atagtgaaga ccccaaatgc
    16801 aaaaagtaga attagacaat ttttcaagaa ggaaagaaga gaagaaaatg ttgaccgtgg
    16861 aaatacaata ttagaaagag aatttaagaa gcatgatata ccacaaaaag accctcttgt
    16921 tgaaaaatat atggcattag ttgctaagaa atttaatcag ccaagtgttg aggacttaat
    16981 tgccactgta ggttatggtg gtataatgtc atctcaagtg gtatctaagg taaaagacct
    17041 atatttaaaa gaggttaaaa aagctaaaaa ggaacaacag atacaagaag aagatttaaa
    17101 taaacacaat ataagtgaaa cagaatacag taaaaagaga aagaaaaacg catcacaagg
    17161 aattatagta aaagggcttg acaatatctt agtaagattt gctaagtgtt gtaatcctct
    17221 tccaggagat gaaattgtag gatatattac taagggtagg ggagtagcca tacacagagc
    17281 tgattgccca aatgcaaaca ataatggtga tttcttccaa aatagattgg tggaggtttc
    17341 atggagttca gcaggaaaag gtaagtttga agcggaaatt caaataaaag ctattgatag
    17401 aagaggaatt gttaatgaaa taactcatat tgttgcaatg gataaactta gtttaaacgg
    17461 aataaatgca agaaaaggta aggatagtat tgtaagtata aacttacttg tagaggttaa
    17521 tgacacagag gaattaaaaa ttctaatgaa aaaattaaaa gcaattcctg gtgtagaaag
    17581 tatttataga atgacaaatt agagttaaaa taatagggag gaaactatga gagcagtagt
    17641 gcaaagagta tcttcatcta aagttacagt agatgaaaac actataggtc aaataaataa
    17701 ggggttacta gtattgttag gagtgactca tgatgataaa tcaagtgatg tagattatat
    17761 gattgataaa atattgaatc tgagaatttt tgaagatgaa aatgacaaga tgaatttatc
    17821 tctaatggat ataggtggag agcttttagt agtatctcaa tttactttat atggagattg
    17881 cagaaaagga agaagacctg gatttagtaa tgcagctaga ccagaacttg caaataacct
    17941 ttatgaagaa tttgtaaaaa aagcaaaaga taaaggtgtg acagttggta caggtcaatt
    18001 tgcagctcat atgatggtag agttaactaa tgatggtcca gtaacaatac tattagactc
    18061 aagtaaatct ttttaagggg gaaaacttta atgattataa aaaaatttgt agatagttat
    18121 tttggagtaa atacttatgt attaggtgat gaaaagacta aaaaatgtgc agttatagac
    18181 ccaggtggaa gtttagtaga gacattaagt tttgtaaaag aaaatgaatt aaatattgaa
    18241 tatattatcc ttactcatgg gcatggagac catataggat atgttaagga tattaaagaa
    18301 aaaactggtg ctaaagtagt tgcacatgtt gatgaaaaag aattattaaa tgataaaaat
    18361 aaaaatctaa gttatacaat gagatgtgga gcgcaagagt ttgatgcaga tatctatgtg
    18421 aatgataaag acaagcttga acttggtgaa ttaaaaatga ctttcttgca tactccagga
    18481 catactcaag gatgtatgtg tataagagtt gaagatgaaa tgttcacagg agatactttg
    18541 tttgctggaa gtattggtag aactgattta tatagtgggg attttaacca aatggaaaaa
    18601 tcacttaaga aattatgcaa atatgaagat gctgttagag tatatcctgg acatggacca
    18661 accagtactc taggggttga aaagaagaca aatccttaca tgtaatttta tattagtatt
    18721 taaaaaagta taaaatattt aataactata ttagtgaggg ggttcttcta ctgttaaata
    18781 gaaggagtta agttgatgtt gtatgttttt ttaaaaggac atgattataa gtatgaagta
    18841 gcagaactta taaaattgtt taccagtgaa tttaagttta aagactctaa tgctaacaat
    18901 aatatagagt caaagcattt aataaataga ttgatttatg agaatggtgt attattctca
    18961 agtactgaat actatgaaaa tggaaactta aagtatgagt caatacagaa tataaaaaat
    19021 atgaatcttg aatttttaga tggatttgat agtagcaaaa cgattgaaga atttcttaat
    19081 agcctagata gtgaaagtaa gaggaacttt aaaaagctgt gtaaagaaaa tatcaaaaaa
    19141 agcatgtttt tagtgcttaa acaagtattt aattcttatg taccatgggg aattttgact
    19201 ggtattagac cagtcaaaat tgtccacaat ttaatggata aaaagctaga tgataatagc
    19261 ataagaacca ttctaaaaga taattatttt ataatagatg agaaaataga tttagctctt
    19321 gaaatagcta aaagagagcg attatttatg tatcctatag ataaaaataa aatttctctt
    19381 tatgtaagta ttccattttg tccaactaga tgtgtatatt gttcatttcc ttcaaattca
    19441 ttaaaacaat ttggacattt aaaaagagaa tatgtttata aattgattga agaaattaag
    19501 gggtttgcca aagttattaa ggagactaag aaagaagttg aaactctata tattggtggt
    19561 ggaactccaa ctacacttga tgaggaagaa ttggatttgc ttataaattc attgttcaat
    19621 gaattagatt taagtaaaat taaagaattt actgtagaag caggtagacc tgacactatt
    19681 acagaacaaa aactaagagt gttaaaaaaa cacaatgtta gtagaattag tataaatcct
    19741 caaactatga atgatgatac tttagtaaag attggaagag agcatagagt atctgattta
    19801 gtagattgct ttaatatggc tcgtagaatg ggatttgata atataaatat ggatataatt
    19861 ttaggtctta tagatgaaga tttaaatatg gtaaagaata cattggagga gataaaaaaa
    19921 ctttctcctg aaagccttac agttcataca ttagccataa agagagcatc caacttaaat
    19981 ataaatatgg ataggtataa agaacatcta acacaatatg aagaaatggt aaaaatgata
    20041 gatttatcaa tgaaatatgc aaaagatatg ggattaaatc catattatat gtacagacaa
    20101 aaacatatgt tgggaaattt agaaaatata ggttatgcta aagaaggata tgagtgcatt
    20161 tataatatac agattatgga agaaaaacaa agtaactatg cattaggtgc aggtgctata
    20221 tcgaaatttg tttatgtaga tgaagataga attgaaagag tagaaaatgt aaaaaatgtt
    20281 gaacaataca ttgaaagagt agatgaaatg ataaaaagga agaaagaaga ggtatataaa
    20341 aatgttgact aaagctccta gaggaactaa agacataact ccaaaagagg cttacaaatg
    20401 gcgttatgta gaaaataaat ttagagaaat atgtgcttta tatggatatg aagaaatggt
    20461 aacacctata tttgaacata cagaactttt caagagaagt gttggagata ctacagatat
    20521 agttcaaaaa gaaatgtatt cttttaaaga taaaggtgat agagaaatta ccctaaagcc
    20581 agaaggtaca gcaggtgtag taagagcatt tatagaaaat aaattatatg cagatactca
    20641 accaacaaaa ttattttatg tgacaccttg ttttagatat gaaagaccac aagctggtag
    20701 acaaagacaa tttcaccaat ttggaataga agcacttgga agtgatactc cttcaatgga
    20761 tgctgaaata atcgcactag ctgttcaatt ttttaatgaa gttggattaa atgatttggt
    20821 agtgagtata aattcagttg gctgtccagt ttgtagaaaa gaatacaatg ctttattaaa
    20881 agagtatctt gactcaaaag ctgatatatt gtgtgatact tgcaatgaga gaagagaaaa
    20941 aaatccaatg agggttatag actgtaaaaa tcctacatgt aaagaaaata tcaaagatat
    21001 accatttatt gcagaccatt tgtgtgatga ttgtaaatct cactttgata aacttcaaga
    21061 atacttaaag gaaatgaata taaactttgt aattgataaa acaatagtta gaggcttaga
    21121 ttactataga aaaactgctt ttgaaattat atctaatgat ataggagctc aaagtactgt
    21181 atgtggtgga ggaagatatg atggtcttgt tgaacaatta ggaggaccaa aaggtataag
    21241 tggaattggg tttggactag gaattgaaag acttttactt acacttgaag gtaatggaat
    21301 tgaaatagaa aaccctcaat ctacggatat atttatagta actataggtg aagaagcaaa
    21361 tacaagaagc tttaaattgt taaaagactt gagacaaaat catataagtg cagataaaga
    21421 ccatatagag agaagtgtta aagcacaatt taaatattca gataaaataa attcaaaatt
    21481 tacaatagta attggagatg atgaacttaa aaatgacact gcgacattaa aaaatatgaa
    21541 aacatcagag caaactactg taaaattaag tacattagtt gaagaattaa agcaaaagct
    21601 gtaaaataag aaagtatgat gttttgtgta ttagataaat atatagcatt aaaattaaat
    21661 aaaatggagg tagtatcttg gaaactttaa agggtttaaa gagaactcac tactgtggag
    21721 agttgagaga aaaaaacata aatgaagaag ttgtacttat gggatgggta cagaaaaaaa
    21781 gaaatttagg tggtcttgta tttgttgatt taagagatac aagtggatta tgtcaaatag
    21841 tttttgatac agatgtagat aaagaagctt ttgaaaaagc tgaaaaatta ggggctgaat
    21901 ttgtaatagc tgtaaaagga aaagtatgcg aaagacaatc taaaaaccct aatatgccaa
    21961 ctggtgatat agaaatattt gcaactgaac ttagactttt aaacaagtca gaaactccgc
    22021 ctatttatat aaaagatgat gatgatgttt ctgaagcact aagattaaaa tatagatact
    22081 tagatttaag aaaaccatct atgcaaagaa atttaaaatt aagacataaa gtaatgaata
    22141 ttacaagaaa ttacttatca aacaatagat tttgcgaaat agaaacacca tttttaatag
    22201 ctccaacacc agaaggagca agagattatc tagtaccaag tagagttaat ccaggaaaat
    22261 tttacgcatt accacaatca ccacaattat ataaacaatt attgatggta agtggtatgg
    22321 atagatattt ccaaatagtt aaatgcttta gagatgaaga cttaagagca gatagacaac
    22381 cagagtttac acaaatagac tgcgaaatgt cttttgttga gcaagaagat gttatgagta
    22441 tgattgaagg tttgcttgaa gcgatattta aagaagtttt agatgtagaa ttggcacttc
    22501 cacttcctaa gatgacttat gcagaagcta tgtctaaata tggttcagat aaaccagata
    22561 ctagatttgg atatgagtta acagatatat ctgatgttgt ttgtaactgt ggatttaaag
    22621 tgtttgctga tgctacacaa ccaggaaaaa gtgttagagg tataaacgta aaaggcaaag
    22681 ctgacgactt tactagaaaa caaatatcat cactagaaga acatgctaag acatatagag
    22741 caaaaggtct tgcttggatg aaagtaggac aagaaggagt aacttctcca atagcaaaat
    22801 tctttaatga agaagaaatg aacgctatac ttacaagaat gaatgctgaa gtaggagatt
    22861 tacttttatt tgtagctgat aaaaactcaa tagtatttga tgctttagga caagttagac
    22921 ttgaagtagc aaataggctt aatctattgg ataaaaatgt atataactta ctatgggtaa
    22981 ctgagttccc agtttttgaa gaagatgaag aaacaggcac attctcagca atgcatcacc
    23041 catttacatc acctatggat gaagatttag acaagttaga agaaggtgat aagtcatctt
    23101 taagagcgaa agcttatgat attgtattga atggttatga aataggtgga ggaagtgtta
    23161 gaatatcaaa ttctgatgtt caatcaagaa tgtttaaagc acttggtttt acagaggaaa
    23221 gagctaatga aaagtttggt tatttattag aagcatttaa atatggtact cctcctcatg
    23281 ctggtctagc ttttggtctt gatagacttg ttatgttact tgcaggaact gataatataa
    23341 gagaagttat tgcattccct aaaaatcaaa atgctgtttg ccctatgaca aatgctccta
    23401 cattggcgga agatgagcaa ttagaagaat taagtataaa agttgatata aaagataatg
    23461 aataatatgt agttgcaaga aactaaaatg taaaaagtct ggatataaag tatatttata
    23521 ttcagacttt ttttattaga attattttat attttttctc tatatatttt cataaattat
    23581 acttgtattc tcaaccaata taattaaaat actatgtcta aaaattttac ataaacttgg
    23641 ttgttttaga aactacttct gtaatgagta cacgatttta attaaagaat atataacaaa
    23701 tttgaaataa gtctaatata tgacttaata gattaaatta aaataataaa tttggactat
    23761 ttatctattt ataacttaaa ttatatcaaa ttgataacaa actagatatt atactttttt
    23821 gtagaataga attacaatta tataaagaaa aattctatta atagtgaaaa aaaagtagaa
    23881 aaaagtagaa attattcttt tataaagaaa gggagggata atattgcaag agagagaaga
    23941 attagtttta aatccagttc caaaagagga aagagttgga tggttagctc cattgtttaa
    24001 tatgcttggt tctaacatag ctatatctga actaatggtt gggggaactt taattttagg
    24061 aatgactctt tctaatatga ttattacatc aattataggg aacttaatat tagttgcaat
    24121 tattatgata caaggttata taggttacaa agaagggtta aatacgtatg tattagctaa
    24181 gggggcattt ggagagatag gaggaaagta tcttatatct ctattacttg gtataactag
    24241 ttttggatgg tttggtgtac aagcaggggt tgcaggacta tcagtacaaa agatattccc
    24301 aagtgtaaac ctaacattag ttacagttat acttggatta tttatggttg tttttgcact
    24361 gtatggtttt aaagctatgg ctaaatttaa ttacttagtt ataccaccac ttatgatatt
    24421 aatggtatgg ggagttttta aagctttttc tacttatgga gttgaagcta tttataatta
    24481 tactcctcaa acaactatga gtatggttga aggtcttaat attgtagtag gtcttgttat
    24541 agttggtgca attatatcac ctgaccagtt aagatatacg agacgagtaa aagatatttg
    24601 gattatcagt tttttaggtc tagggattat ttcattattc caacaagttg cagctggtgt
    24661 aatgtctatg ggagcaccta cttgggatat aacagaagta ttggctaatt taggttttgg
    24721 atgggtagcg tttgttattt taatacttgc atcttggtca acaaacgtat caaatgctta
    24781 ttctggtgga ttagcattaa aaactatttt tccaaatgta aaaagaaatg ttttgacttt
    24841 agttgcaggt ctaataggta caataatagc agctactggt ataatattta aatttcagtc
    24901 atttttatct ttcttgggaa tcgcagttcc tgcaatagca ggaattatgt ggtgtgagta
    24961 ttattttata caaggaagaa cttataagca tagagaagga ataaattgga ttgcagtaat
    25021 aagctggtta ataggttttg cagcgtcgta ttatagttca aaaataaatt tcttaatacc
    25081 tccgataaat ggaattgtag tgagtatggt tatttattat atattaatga aatgttttgg
    25141 aatcaaagat aaataaaggg ggcaattaca tgggtcgtaa ggtgaaaata ggtataattc
    25201 aacaacacag tgtacttgga gatgttaaaa aaaatataga aaaggcagta gagatgatag
    25261 atgacttagg aaaacaaggg gcagatataa tttgtttacc agaactattt gctacaggat
    25321 ataatttaga gtctttaggt ggagttaaaa cattagaatt aataagagaa cataataagt
    25381 acatagagga atcaatgtca gaagctgcta aaagaaataa tgtatacctg atatctccat
    25441 atggaacctt agaaaaaggg tctacacatg tttataattc agcagttata tttgatagaa
    25501 aaggtaagat tatgggagaa tactgtaaaa atcatctgtg gtcattagaa gcagtatact
    25561 ttaaaggagg ggaaaaagta gaggtatatg atgctgattt tggtagattt ggtgtaatga
    25621 tatgttatga tgcaggtttt ccagaagtat ccagagaatt gacattaaaa ggttctgaaa
    25681 taatatttat accatctgca tggagaatac aagatgaaga tatgtgggat ttaaatgtat
    25741 ctcaaagagc tttagagaac actgtatata cagtaggtgt aaatttagta agtaatgact
    25801 ctaatttaat actatttgga aagagtaaaa tatgcaatcc tagaggtact gtaataactc
    25861 aattagatac atacagggaa aaatatgtat tatcagagat tgatttagat gaaataaaaa
    25921 agtataggga agatatcccc tatttgaaag acagaaaaag tagctataac atataattct
    25981 atactataat acaagttcaa tataaaatga taaaaagagg atgtatcaat attaagatta
    26041 aatttattat actttgatat atcctcttta atattatcaa ctttgattta aatattttta
    26101 aaatagttga taagaaagtt tttgaacaac aacacagctt tagattcata gttttcgcta
    26161 aaccatgaaa gatttaaata tcttttaaat tcaatatctt tgatatgtaa caacttaatc
    26221 tcagggtctt gagataatcc ccatgatttt ccacatataa atccaactcc ttgaagtgat
    26281 tttataagag cataaattgt atatggtgaa tcagactcaa atgctatttt gggtttgaaa
    26341 ttagctgatt cacacaggat atcaattacc tctctataat tctcaccctt cgttataact
    26401 ataaagtttt catctgaaac ttcgcttaga tatacttcat cctttaatga taaaggatga
    26461 tttattgaaa ctcctaatag tatttcttcg catgttaaag ttatgctatt ttctgagttt
    26521 agctttgtaa atgaagaaga tatgtacaaa tcaaaatcac tttttttata agatgatggc
    26581 aaagtatgtg acacattaaa agtaatattg ggatatagtt ttctgaaatt actcaaaagt
    26641 gatggtaaca cattagccgc tgcaggagat aatatcttta cttctcctga attttctaaa
    26701 gaagtgtctt gtaactcctt ttttgaactt tctactaaat ctaaaatgct atctactctt
    26761 tttagaaaca atcttccata ctcatttaaa acaatatatc ttccttttct gtcaaataac
    26821 tgaactccaa gttctttttc taaggaagat atagttttgc ttaaagctgg ctgtgctata
    26881 tttaacttgt gtgatgcttt tgttatgtgc tccattctag caacagtttg aaaatactta
    26941 agatgcaata aatccatagt ataaaataca cctcttttaa tatgacttga gttatatcaa
    27001 ttttataatc aactccacat tatacattat aatataaagt ttatataata aactacaata
    27061 tattaaaaag ttatttaaat tgttatttat attttgtaca taatctaatt aaaaaaagta
    27121 actttaaatg attaactaag gaaatgttgt tacaaacttt agttatataa aaaattcatt
    27181 tgatgagcaa agtattaatg tcaagtaaga ataaaagctt attagataag aaaaataata
    27241 ttttataata atgatgttac ttaaattatt atgttatact attttaaata ggaaacattt
    27301 agatactata attttagggg gagtcaagat gaaattaact aaatcaatat catcaatgct
    27361 gtgcttatct ctagttttaa gcttatcacc agtagcatat gcaaatgaaa taagtagaac
    27421 aacagttgag aatactttag taggtcagga tagatatcaa actgctgttg aagtaagtaa
    27481 aaaaggatgg agtagtgcaa atgaggctgt agttgtaaat agtgaatcta ttgtagatgc
    27541 attagctgta acaccatttg ctaaattaaa aaatgctcct atattattga cagaaaaaaa
    27601 tgatctaaat tcacaaactg agaaagaatt aaaaagatta ggcgttaaaa aagtttatat
    27661 aattggtcta tctagttcta tatcaaatga tgtgcaaaaa cagttagaat ctaataattt
    27721 aactactgat agagttggtg gtagtgatag ataccaaaca gctttgagta tagctaaaaa
    27781 aatagaagga ttaaaagata tatcagaaat agctgtagta aatgggtaca caggtcttgc
    27841 agatgcagtt agtatagctt ctgtagctgc tactaatgga atggttatac ttccagtatc
    27901 tgatgcatct ggtatatcta gctttaaaga ttttatagaa tctaagaata taaataaatc
    27961 atacataata ggctctacta atgctgtatc agataaaata aaacaaagtt tacctaattc
    28021 agaaagaata ggtggagcag atagaaatga aactaatggt aaagtaatag aaaagtttta
    28081 tacatctaat aaattaaaca atgtatttgt ggctaaggat ggaatgaaaa atcaaaatca
    28141 acttatagac gctctagcag taggagtact agcatcaaaa gaaaattctc ctgtactaat
    28201 cgtaggagaa caattaagtg caacacaaaa gagtgtattt tcgaataaaa atgctacctc
    28261 tataactcaa gttggtagtg gaggaaatga aaatgcattt aaagaattaa aagatttaca
    28321 ggcaaatagt aacaataaga gagtaatgta tgtaactaat acagataagg taaatataag
    28381 aaatgatgct acaatagaag cttctgttat aggatatcta aataatggtg atgaagtaga
    28441 agttttagat gtgttaaaaa ctggatgggt aaaaataaaa tacaatgaag gtattggata
    28501 tgttagtggg tcttatttga caaataataa gcctgataat agtaatgaaa atataaaaat
    28561 aaagtatgta aaagaaaaag atggtctaaa tgttaggaaa ggaccaagta cagaagatga
    28621 aaagataggt cacctttcat atggaagcaa agtagaaaca atagaaatgt ttgctactgg
    28681 atgggtaaaa ataaagtata atggtggata tggttatgta agtaatgatt acttatctga
    28741 tacaccagtt atttaattat aagtaacaat aaaaaactgc tttaatttgt aaagcagttt
    28801 ttttataaaa atttaagtct aataactatt tctattttga taccttaatc ctgggattta
    28861 ttattatgga tattatcaac atacaaacac tccaaatcca gtgtctaatt ccaaacttag
    28921 atattaataa attcagtcct gctatggtaa ataagcagta tttaattaca attaaaagtg
    28981 tatttataga aagccccttc atagaaagta tcctaaatcc aataatagac attctaagtc
    29041 ctataaatgc caataatata cctgcaatat cctgaattaa gtaatagtat tcaaatttca
    29101 tattcaatca actcttctct gagcagtatc aaatatttct aactcttcaa tttcatcatc
    29161 tgtgtatgta agcatagtaa aaccagttac accataaata aatgaaatta taggtgtaat
    29221 ccaacttaag aaacaatatg gaataaattc tagtgggctt acaccaaggg tctgagcaca
    29281 gaaaacagca tttgaattcc atggtattaa tggaccacca agtgtagctg tatcttctat
    29341 aattctagat agattttgtg gttttaattt aaattctttg tatattggag acattagagt
    29401 tccgacaaat acagaagtga acatcattga tgaactaaat gcatttgcaa agtagcttac
    29461 tacaaaagta gacccaacca atttagttct tgattttcct attttagtta taagaggttg
    29521 aagcagtact tctaagaatc cagttttttg gagaatacca gcaataacga aaactacaaa
    29581 tactagtaaa acggtttcag ccatactcat tattccacca cgatttaata gtttgtcggc
    29641 atagacaaat ccagtatcta tagtaaatcc tgatagcatg taatttaaaa catcacctat
    29701 tttttctcct tcttgaaata ctgctataat aagtcccatg atagctgaac ttagtataga
    29761 tataatgggt ggcttttgta gcaataaaag taataataaa aatattattg gaatcattgc
    29821 tactaaacca atatgaaagt ttgaatttaa tacatccttg atttgattta tttgaacata
    29881 gtctatagta ttatttgaat acttaaatcc aattactgta tacagaacta tacatattac
    29941 gtatgcaggt cctgtggtat aaaacatatg cttcatatgt gtaattacat ctgtcttaca
    30001 aactgctgca gctaagtttg tagaatctga tagaggtgac atcttatctc caaagaaagc
    30061 accagaaatg actgcaccag ctgttaaacc aagaggaata cccatactag taccaatact
    30121 catcattgct ataccagaag ttccaagagt cccccaagat gtaccagtag caacagaagt
    30181 taatgaacat acgattaatg ttgtaagcag aaaatattta ggggttatta ttgttagtcc
    30241 actatatact actgttggta ttgtaccagc agctatccaa gctgctatta gtacaccaac
    30301 agaaagtata attaagtttg attgaaaggc atctttacca acttcaaatc caaaagcttc
    30361 tatttcatca ttagtataac caagtttcat ggctgcagga actactataa gccatgaaag
    30421 taaaaacatt gtagttatag aagcattaaa tacaactata ccaactgatg ttagagctat
    30481 tattgcaagc attactaaca aggaatatct aaatgaaggt atttttcttt ctgtattcat
    30541 tttcatagtg caaattctcc ttaaatattt ttagttaatt gcatttttta ttcttataag
    30601 agcttcttca agcatacttc ttggacaagc taagtttatt ctttgatacc cacttcctcc
    30661 aatgccaaag ctgtttcctt gatttagagc aactttacct ttttgtacaa gtatactttc
    30721 tagttcctca tcacttaatc caagtgcact aaagtctacc cataataaat aagtaccttc
    30781 tggttttcta actttaagtt ttggcatatt ttcatttata tattttatag caaaatctat
    30841 attagattct aaatattcta aaaatgattc tagccaagat tcaccattat tatatgaagc
    30901 ttcagttgca actaagctaa agcaattatt tctctttata tcaattctgg taaaggcatc
    30961 atctaacaat ttatagtctt tttcatcagg tagtattaca tatgatgatt gaagaccagc
    31021 tatattaaaa gttttagttg gagccataca agtaattgta tttttttcaa attctttaga
    31081 aatagatgcc ataggaatat gcttatgttt ttttaatata atgtcactat gtatttcatc
    31141 agatatgatt tttacattat gcttaagaca aatatctcct agttttttta attcatcttt
    31201 tgtccatact ctaccaactg gattatgagg attacaaagt atgaataatt ttacatcttt
    31261 aatcttgttt tcaatgtctt cataatccat tatgtagttt ccgttttcta gtttttgtaa
    31321 tgggcttata attagttctc tattgttatt ttttacaaca ctattaaaag ggctgtaaac
    31381 tggttcttgt atcattattt tatcatttgc tttcgtgagt tcatttatta aaagacttat
    31441 agctgggata acacctggac tataaattaa ccactcactt tttattttcc agttatgtct
    31501 cctatctagc cagtttacta tagattcatt gtaagaatct ggtcttgttg tgtagccata
    31561 aatctcttgt tctagtctat tttttaagga atcaattata caaggtgcag ccttaaaatc
    31621 catgtcagcc acccacatag gaagtaaatc attagttcca tacttttttt ccatttctga
    31681 ccatttagat gaaaaattat tgcttctatc aacaatctca ttaaaattat aattcattgt
    31741 aaatacctcc agtaatttta attttatgtt aataatatta agcaaacaac gtgccaatat
    31801 tgataataaa aaatatttat tcacaagtta atatttaata ttaagtaatt tcagagcata
    31861 gataagataa aaatattaat tatacttaaa actttgtgga aaaggttatt tctaataaat
    31921 ttttaaatat atgaaaatgt aattaaatag gttaaatagg tttaactgtt taacttgtta
    31981 gacctattta tattttttag aaattctact ccttttgatg ttataattga acctccacga
    32041 ccaataagta tgtctacaag cccaaagtct tgtagttcta aaagcatatt tctaatctgt
    32101 tgttctgtca aaaatctatt ttcctctaaa gctattttac ataagctttt tctacctatt
    32161 ctttctttta aatcataagc cttttttaaa ttatccaata taaatatgta ttcatctagt
    32221 gactttttaa aattatagtc gtattccatg atgtttttgt ctttgccaat gttgaattga
    32281 tactttttta tattatcact tactttatta caaacggttc tactataatt tgaatctata
    32341 gtatccaata tatattcagg taaatcacat atttctataa tatctttttc caagtaacag
    32401 aagtattctc ctaagtttct taattctctt acatttcctt cccatctata cattttaaag
    32461 atttctttta cttcctcact tagaataaaa ttacatggaa tatcatattt taatgaacca
    32521 aaaatttcaa atatatcagc aggtctttcc ctaagtggat gtattttaag gggaagaaca
    32581 ttcaacctaa aatataaatc tcttctaaac atatttttag atacaagttc ttttaaattt
    32641 ctattagtag ctgcaattat tcttacatca atgtcaatga cattattaga accaatacgt
    32701 cgtacttgtt tttcttgtat gactctaagt aatttagatt gagaatttaa atccatttct
    32761 ccaatttcgt ctaaaaatat agttccattg ttggctaatt caaataaacc aattttccca
    32821 ccttttttag caccagtaaa agccccttca tcatagccaa ataattcact ttgcagtaga
    32881 ttttcttgaa aagtactaca atttactgcg acaaaaggac catcttttct cctagaagca
    32941 ctatgaatgg attgagcaaa taattcttta ccagtaccac tttcaccaat tataaggata
    33001 gatgaatttg attgagccat tttattagca attttttttg tattaatagt ttgtatacta
    33061 gaacctaata tgtcatcaaa tgtgtattta ctgatattac cagagtttac tagttgtgct
    33121 cttaatttag cttgcttttt ttctaattga gaaaactttg tcatctttag tataaatcca
    33181 tcaaatacat ttaattgtat atgtttaatc tctaaattta tatcaatatg atttatttta
    33241 atcaatttct caaaaaatgg agttttattg gtcaatatgc tttgaaaatt gatgtctttt
    33301 atgcaatcac caacaaatga gtcaatcatt tcatttgcat ttatagacaa aatttttcta
    33361 gccatatgat tatagaattg aattattcca tcgttatttg tgcatataat tccatcatca
    33421 attatagata gtaacaaatc aaattgtctt tcaaacttat ttgcatctaa caataactca
    33481 cctgtactat aacttgtagg aattattttt tctacgtatt tttttattag gtcatctttt
    33541 attagatgtt ttaatttggt ttttgtagca atttcaacaa tacaacttaa atctattatt
    33601 ctgtatttta aatctataac ttcacaattt ttaaacttag gcaagatttt ttcgccagga
    33661 gttaggatta cagcatctgt gggagtaaac tcaatctctg gatagcaggg caggatattt
    33721 atattgtcta ttcctaatct atgtattaaa gaaattgttt ctattgccat atctttactt
    33781 aagttatata cataaataat tttatctttt tctaatttgg atatcatatc aatactgttc
    33841 ttttcaaatg tcaacttggg aacaatgatt tgagcatcat agtgagataa ttttactatt
    33901 tcatcatatt ttaaataagc agataggagt ataagttttt ctttaaaaaa ctttaaattt
    33961 ccctcttcaa atgagtataa atttatcttt agattatcac ctaagaattg ccttatttga
    34021 ttttcataaa tttctccagc gtcttttttt aaacttacaa tagctaattc catttgtttc
    34081 attttaacct ctcatacaaa tttgacttat tttagattac ataataatta aattaaataa
    34141 tattatttaa ttattattat aaatttatta tagactacac attgaagtaa aagaagtagc
    34201 taaaattatt ccttttattt ttgttttttg tatctatttg gtataatagt attagagcgt
    34261 ataataattt aggcaaaatt ttttaaggaa gactagagga gaatataaaa tgaaaaaatg
    34321 tctttactgt aatagggata taaagtcacc aaataataaa ttagctataa aatatgatga
    34381 caatatgaat atatatccat gtcgtgcaga atgtaaggaa aaaattgaag aatatatagc
    34441 aaaaaaacct acatataagt ttataaatat attagaggtt cttttaggtg tgggcggaat
    34501 attctgcttt ttgagtaaat ggactattgc agcccaagtt gtacttggaa ttgatgcact
    34561 ggttatattt ttattcccat tggcaggatt taagatgaat ggaaagttaa gtatggaaca
    34621 aactaagaat caaagtaggt ctattgcaat atcaattttg gcatttatag taataataac
    34681 tgtattatat tttaaacaag ttggtaagta gagcataatt gtataagaca tcattagagt
    34741 atgaggtgag tttatggaag aaagaaaatt agcaccaaac aatgagaggg aagctctcat
    34801 aaaaagatta aaaagaatag aaggtcaagt taagggtata caaaagatgg tggaacaaga
    34861 acgttattgt gttgatatat tggttcaaat atctgctata aggtctgcta taaatagagt
    34921 aggcacaatt atcttagaga atcatataaa aggatgtgta gcagaaagca ttaaacatga
    34981 tgatgctgat aaaactgaag agatgataaa agagcttatg gatactataa ataaatttac
    35041 aaaataagga ggcggttagt tatgaatcaa caaggattta ttatggaaat tgttgatgat
    35101 agaactgcaa agttaaaaat gcaaagacat tcagcttgtg ctgcttgtgg aaaatgtgct
    35161 actacaaatt cagcagagtc aaaagaaata ttagtagaag tagacaacac aattggtgca
    35221 aaagttggtg accatgtaga agtgagtatg gataatatga atgtattaaa agcagctgta
    35281 atggcttata taatacctct tatagcactt cttgtaggaa caatagggac ttattatata
    35341 ttgggggcaa ttggaatgac aactggagtt gaagccataa gtggattagt tggaatttgt
    35401 cttacaataa tctgttattt atacttaaag aagaatgaca aaaaatttag agacagtaga
    35461 gaatttatac cagtaataac aagaatatta attgatcttt aagataatta taattaaaaa
    35521 atagcaatgt gctttttaaa taaatactca atacgtattt gtagagttta agtacattgc
    35581 tatttttata tttttatttt gattttctgt aaggaataaa gttttttctg attttcaaaa
    35641 gattcaatgt tcttacaaaa gaagttacaa ctaatacacc aagtgctatt gcagcactta
    35701 gaaatagcgc atctgtacct tttgacatag ccaaagaata atttttctga atcaaagaca
    35761 acattgtatt atatagccca attcctggta ttagaggaag aatacctgga attacgaaca
    35821 caatagctgg ttgctttagt tttcttgcta aagtctcact gcacgctgag accaaagcag
    35881 cagcgataaa acctgcaaaa actgcatttg tagtaaaatt aaataaataa acatatacaa
    35941 tccaaccaat tccgccagtt actccagctg gaagaagtag atatagtgga gcattaaaga
    36001 aaacagcaaa tccagcagtt gcaacacctg aaaataaaaa atgcaaaatc atagacatat
    36061 cagtcattag aaaggacctc ctattctata ccatgtatca aggacaaaac caactccaga
    36121 agcaattgca ataataatca tagcagcatc aaaagcacga gaaattcctg atattaaatt
    36181 ccctgatatt aaatctctaa tagcttttat aaaagcaact cctgggagta gtggcattat
    36241 agcgccgact ataagcattt tagggtcatc taaaatgcct atttcaacta gtagaactcc
    36301 tgaaagtgca attaaaaaag aagatactaa acaggaaaat gcagatattg cacttatctt
    36361 catcgtttta tcataagtaa ttgcagcaaa gattgctatt ataaacgtaa gtataaaatt
    36421 taatacataa ttccctccaa gcaaacaagc aaaacaagca gatgcaattc ctgtacaaga
    36481 gtaaaataac cataaaggat aaggttttac atcttggatt tcataaagac gtgcaatggc
    36541 attatcaata tcatactctt tgtcactaac aaattctcga gaaaaactgt ttaataaaga
    36601 aatcttattt aagtttatac ctcttgattg aatcgttttc ataaacgaaa agccatcaaa
    36661 tttctcatct gaaataatta ttactgtagg agttgtaaaa atatttacat gataaaaccc
    36721 tcttgacctg catattctaa ggacactgtc ttcaacccta gatgtttcag ctccattttt
    36781 tatcatcagt tcccctacaa atagagctag ttttagaata tttttcttat attcaagttc
    36841 ctcattttga ttcataaata cacctccaaa ttaaaaaacg taatattgaa attatatcaa
    36901 atttttaagt aatattcctt aatatctata taaatatatt atcttttttt tgtttcaaaa
    36961 tagtcacatt taaattatat ccaattaaaa gaattagaca atattattta ttatatttta
    37021 acttaaaaat aaagaaagta actatgttaa atatggaaaa atggcaaaac acttgactat
    37081 taattggtaa aggactataa taataaatta tcatattgat aaaaacgaaa attatgaaat
    37141 gtctgtaaaa ataaaattta aataataact aggaggagta atatgtttga gaacttgaaa
    37201 aaagcggacc ctgagattta tgaaagtatg aaaagagagt taaaaagaca acaaagaaat
    37261 attgaattaa tagcatctga aaacatagta tcagttccag taatggaaac tatgggaagt
    37321 catcttacaa ataagtatgc agaaggttac tcaggcaaaa gatattatgg tggatgtgaa
    37381 tacatagatg aagttgaaac tcttgcaata gatagaatca aaaaaatatt tggagcagaa
    37441 catgctaatg ttcaacctca ttctggagca aatgcaaata ttggtgtata ttttgctatg
    37501 ttaaaaccag gtgatgttgt tatgggaatg aatttatctc aaggtggaca tttaactcat
    37561 ggtgctccag ttaatatttc tggtcaatat tataaatttt atgaatatgg tatagataaa
    37621 gacagtggac ttatagattt tgatgaagtt agaaagatag cacatgaagt aaaacctaaa
    37681 atgatagttg caggagcaag tgcatatcct agagaaatag attttaaaaa gtttagagag
    37741 atagctgatg aggttggagc attgcttatg gtagatatgg ctcatatagc aggtcttgtg
    37801 gctgctggtc ttcaccaaaa tccatgtgaa gtggctgatt ttgttacaac aacaactcac
    37861 aaaactttaa gaggacctcg tgggggtgtt attctttgta aagaaaaata tgctaaagac
    37921 atagacaaag caatattccc tggtattcaa ggtggacctc ttgaacatat aattgcttct
    37981 aaggcagttt gctttaaaga agctttaagt gatgagttta aagaatatca ggtacaagtt
    38041 gctaaaaatg caaaagcctt agctgaagaa cttattaaaa gagattttaa attgatttct
    38101 ggaggtacag ataatcattt aatactatta gatttgacta ataaaaatat aactggtaaa
    38161 gcagcagaaa agagattgga tgatgcttat ataacagcta ataaaaatac aattccattt
    38221 gacccaaatg gtgctcttgt tacaagtgga ataagacttg gtactccagc tgtaactact
    38281 agaggtatga aagaagaaga tatggcaata atcgctgagg ctatagacct atgtttaact
    38341 tatgatgaag aatctaaggc tagaacattg gttgttggtt taactgaaaa atatccttta
    38401 tatgaagaat ataatattat ggattaatta taaagaacaa ctaaataaaa tacatttaaa
    38461 taattacaat gattgtgtat gtatttgaat atatttagat ataaaaaagg tgtctcaaaa
    38521 tgaacttttt agtttatgag gcactttttt gtatggaatc gaacatattt gtattattta
    38581 aataataaaa aatatggtta tctctatttt tagatggtct ctttgtattt tttaattaaa
    38641 actttaagat ttcttaagaa ttatactagg tttttctaaa gatttaaagt ctatacttat
    38701 aagtatagta atcacatgaa aagaaaagct ttaacgagga gggaatctta tgaaggtatt
    38761 aattcttaca ggaaaatttg gtatgggtca ttactcagca tcaaattctt taagtgaaga
    38821 tataaaagca aaatttgata attcagaaat aataattaaa gatatatttg agtacattat
    38881 gcctaactat tcagataaaa tgtacaagac tttttctatt cttgtaaatc ggggaagtag
    38941 tctttataat ttattttata aatgtgctga aaatggaaag aaagatataa aatttacttt
    39001 ttcagattat tttttaaata aattagatac attacttcat gaagtacaac caacagtagt
    39061 tatttcaact tttccatttt gttctcaatt agtatcaaga tataaggaaa aatataactc
    39121 aaatcttcct ttaataacat gtataactga tataagtagt cactcagaat ggattagtaa
    39181 aaatacagac tgttatttag tagctagtaa atctactaag gaagaacttg tttttaaagg
    39241 aatagatgaa tctaagatta aagttaatgg tattccagta aaaaaagaat ttaaaagaat
    39301 agaacatgta aatcattcaa ctaaaaaaaa tattcttata atgggtggag gattaggatt
    39361 actgcctaaa tcagaacaat tttacaaaga attaaatagt ttagaaggag taaaaactac
    39421 tgtaataact ggtaataata aaaaaatgta ctataaacta tatggtagat atgaaaatat
    39481 agaggtagta ggttacacca atgaagtata taaatatatg aaagattctg accttattat
    39541 ttctaaacca ggtggaataa cactatttga aacaatttat tcagaacttc caatattggc
    39601 atttaatcca tttttacaac aagagataga taatgctagt tttatattaa ataatgaaat
    39661 tgggagaata cttggtaaaa ataaaaaata ctatgtagat gagataaaag atttaattta
    39721 tgatgatgct actcttaaag aaatgagcag taacatgaaa gaattaaaaa aacaatttga
    39781 taataatacc ttagagaata ttttattttc acttgatgaa caaggagcgt gtagagaatg
    39841 tatgtagtag gtttaattat cgttgttgca ttgatttttt tagtccattc aattatacct
    39901 acatactata ataaactatt aaataaagag gtattaaaaa atatggctgg agaaaatgaa
    39961 attgcactta catttgatga tggtccagat aagagatata cagaaaaatt actagatgtg
    40021 ttaaaagaaa atgatataca agctatgttt tttgtagtag caaagaatgc tgaaaaagag
    40081 cctgaaatta taaaaagaat gttgagagaa aatcatatag ttggtttaca ttcattggaa
    40141 cacagaaatg catggcttta tagttatagt tatgttaaaa aagattttat tgaaagtaca
    40201 aatataatga aaaatttagg tgtagatgta aactactatc gtccaccatg gggtcatact
    40261 aatatatttt caaattcatt tgttaaaaaa tataatctaa aaatgacttt gtgggatgta
    40321 atggcagaag attgggagaa agatagtaca gtagacatta ttataaacaa gttaatgagt
    40381 agaacaaaag aaaattctat aatttgttta catgatgcag gtgaaaattc aggtggtgca
    40441 gtaggtgcac ctgagcgtac tattgaagct ttaaagatag ctattccaaa acttaaagcc
    40501 agtggtttaa agttcgtaac accagaaagg atgtagttat gataagtaaa actgaaaaga
    40561 aaaataaatg cctaggtagt gtagcttttt tagttttact aatgggcata acaggatatt
    40621 ttgtttttag agggcagtca gttgaatcat tgataaaatc attaaaaggt gcaagcccta
    40681 tgtttatact aattggattt gcaatgatgt ttatatatgt tgcctgtgaa ggtataaata
    40741 tatacttagg tatgaaagct ttaaaccaaa agactactct tttaaaatgt atgggatatg
    40801 cttttattgg attttatttt agttctatta caccttcagc atcaggtggt caaccagcac
    40861 aagtttatta tatgaaaaaa gacgatataa atatatcata ttcttcactt atactattag
    40921 tcattgttgt tattcaccaa gtagttatac tggcatatag tggaataatg ttcattatgg
    40981 aacgtgagtt tatattaaat aatgtaagtg gtatgaacat tttactaata tatggtgtaa
    41041 taacaaatgt tgctcttgtc attggagtaa ttgcaattat attttcaaaa aaacttgtaa
    41101 acaattttat aatatcaata acaaatttat taggtaagtt aagaataata aaagatgttg
    41161 aaagttcaag aaaagttata atatctcaaa ttgaagagta tgttaaaggt gctcaatata
    41221 taaagcagaa tccaaaactt gtagtccaaa ttttagtcat aactattgta caaataacag
    41281 ctatgttttt agttcctttc tttgtataca aagcttttca tctatcaaca tatactgtat
    41341 ttgagatatt agcgatacaa tccttgctta atattgctgt ttcttcatta ccattgccag
    41401 gggctgttgg agcttctgaa aatagtttta tgacattatt taagatattt ttccctggtc
    41461 acttattagt tccggcaatg ttacttagta gggggataag tttttatgca tttgtagcta
    41521 taagtggatt gatatgtata gtagtacatg taaaatcttc tgaaaaagta aaagcagtga
    41581 aaaaagttgc ttatgtaaga taatattata tagattattt ttattaatat gtcaatttgt
    41641 gtgtatattt taattaagct ttaaacatgt ttacaggagt agaaactatt aaaacgtgtg
    41701 acattgctaa gcttttgcta ataaagtata atattttata tagtttgaaa tatttaagaa
    41761 atatagcaaa aaaaggagct tggtgatgaa taaagagatt ccaaaaaaaa ttttagtagc
    41821 tgatgataat cctgagatta gggaaatcgt agaaatactt ttaactggtg aaggttatga
    41881 agttattatg gcaacgaatg gagaagaagc tgtaaactta gtagatagta cgattgattt
    41941 gattattttg gatgttgtaa tgcctgtaaa aacaggattt gttgcatgta atgaaattag
    42001 agaaaaaacg acagcaccaa tattattttt aactgcaaaa actcaagact ctgataaagt
    42061 tattggattt tcagcaggag gagatgacta tttatcaaag cctttttcat attctgaact
    42121 aatttcaagg gttaagtctc tacttagacg ttattatata taccagggaa aggaaaagga
    42181 aagagagcca aatatattaa aaacaaaaga gttatgtgtc aatttagata ctcaagatgt
    42241 tacactaaat ggagaacctg tgtttttgac aactatagaa tatagtatat taattcttat
    42301 gttgaaaaat agaaaaaaag ttttttcgtc tgaaaattta tatgaaacta tttgggatga
    42361 gcagtatttt tatacagcaa ataatacaat aatggttcat attagaaatt taagaaaaaa
    42421 gttagaaaaa gaccaaaaaa atccacaata tataaaaacc gcatggggaa aggggtatta
    42481 tattgattaa caaaattaag ccatctaagt tgggagttat actattgata tatgtagtaa
    42541 tctcagctgc agtggctttc attttaaata taccatttta ctctgctgtt gaatctatag
    42601 taaaagatgt atcagaaggg aaagtatatt ttaaaagaga agtaaatcaa cttatggata
    42661 attttcaaac ttatgtgaat aacaatggta taagagcaga tgatggagat gatatagcaa
    42721 aatggaatag tgataattgg tttgtttcta tgaagatata taaaggaaat aaggtttttt
    42781 atgatacatt atactatcct aatgaagtac ctgataagag tgaggaaaat gagttttata
    42841 gcagtcccat ggctagaaac tatgagatac aattttctga tattaaagct aatatagttg
    42901 tagtagcttt atttagattt agatttcaaa attttataga agcaatttct attacattta
    42961 tggcacttac atttattata acatttttac tgttgtttag tagaaagata aagtacctaa
    43021 ggaaaataga aatgggtata aagatagtag agagtggcag tttaaagtat agaatcccag
    43081 taaaaggtaa tgatgaatta tcatcacttg catctagtat taatgagatg agtcatacat
    43141 tggagaatca acttataaaa gaaagggaga tgaagaataa aaataaagat atagtaactt
    43201 cgatatcaca tgatgttaga actccattaa cgtcagtaat ttgttattta gatttgatta
    43261 aagaccataa atacaatagt cctgagcaat tggaacaata cataaaaaat gtaaggtcta
    43321 aagcatatca aataaaagat ttaacagatg acctttttac gcattttgtt aattctggag
    43381 aggaagtttc aaaagggtat gaaaaaataa atgctaatga atttattttt caattacttt
    43441 tagatagttc atatacattg gaggagaaag gatttcatat aacaatagaa aatgaacttt
    43501 ataaccaata tcatatttat gtagatgtta cacaatttag aaggatattt gataatttat
    43561 gttctaatat aataaaatat gctaggaaag ataagcctat agtattttta attaaagtag
    43621 aggattctaa attactaatt atacaaaaaa atagagtaag taatttttct aagaatgtag
    43681 aaagttttgg aattggtata aagaattgtg agaaaatagt tgcatatcat aatggaagca
    43741 taaatgtaaa ttcagatgat aaagaatttg ctattgaaat atctattcca gcaaaagaat
    43801 cataaaaatt taaattatat attgtgtaat tgcttatgta aaattctatg aagcaggaag
    43861 catgtgactt tagttatggg atgttcaata ttgtgtacct ctaggcaagt aacaagttta
    43921 cttacaagac catataatat tattatctta aaaaaagggg acataataat atggttttga
    43981 caggagcaca ttatatttac attctattta tggtaattat attaattact atgattatga
    44041 aaaaggatac aatagtacca tgtatattag gtgttttttt tatggggttg ttctttgaaa
    44101 aaaacatttt tggtgctata acagcagtgt ttaactcttt tattatatct ttaaatgagt
    44161 tgggtccaat tatcttgatt atagctatta tggttgcatt atctaaagcc ctagaagcca
    44221 ataatgctat acagtatatg gtgagaccat tttcgagagt tataaaaaat tctaatacag
    44281 cattttttgt aactggattt gttatgttag ttctttcttg gtttttctgg ccaactccag
    44341 ctgttgcctt agttggagct gtatttttac ctgttgctat gagagctggg ctaccagcaa
    44401 ttggtgttgc agtagcatta aatttatttg gtcatggtct tgccttatct acagactttg
    44461 ttattcaagg agctccaagt ataacagctg gtgcagcagg tgttgcagta tcatatgtta
    44521 taaatgatgg tatgattttg ttttgggtga tgggaatcgt aaccatatct atggcatttt
    44581 atacattaaa aagagatatt aacaaaggaa tgtttagaga agaactaaaa ggttttgaaa
    44641 gtgaagaagt agaagagttt aatggaaaat ctaaaatagc aactatttta gtagctttgg
    44701 gatttcttgc tgatataatt gctatgtatg tatttgacct aaaaggagga gatgcatcag
    44761 ctcttttggg tggaacagca gtatttttaa taataattat aaatgttata aattttggca
    44821 aagatagtct tgaaaatgta tgtgagaata taattgatgg ttttgtgttt gggataaaaa
    44881 tatttggagc aattatacca atagcagcat ttttctatat gggtgaagtt gcaccattga
    44941 caggtgtatt tggaaaagta ttagcaccag gttcacaagg tttattatca gatataggca
    45001 tagctctttc tcaaacaata ccacttaata aatttgccgt atcaggtata gaaactgtag
    45061 tgggagcaat aactgggctt gatggttctg gattttctgg gatttcatta gttggttcac
    45121 ttgcctctgt atttggaact gctataaatg caagtgttgg tgcactagct gcattaggac
    45181 aaatcagtgg tatatgggta ggtggaggct gtctagttcc ttggggtctt atttcagcat
    45241 cggcaatttg tggagttagt ccaatagaat tggcaaagcg aaactttgtc ccagttataa
    45301 ccggattggt tgtaacaacc atagtagcaa tgtttattat ttaataaatc gaataaatct
    45361 ttaattgtat aaattaaaaa tagatgtgta gctataattt attataattg ttttactaat
    45421 tctaagccat acatctattt ttattgatat ttttattagt attctttaat aaaataatat
    45481 ttttcattat actatacata acatctaaat ataacatcta aaatactgtt atctatattt
    45541 aatatcttgc caaatttttt gatgttttat tgccctgtcc caccaacata tataagctat
    45601 cacaagtttt tacctatact atcaccaaac aaaaattcta attttaattt attattttat
    45661 aacctatatt atattaacta tattagtttg tagactttag atgtaattat aaatattaat
    45721 actccaagag ttcaaattca tatcctagtt ttcttgcatt tgatataaaa tcatttaaaa
    45781 tttctgtact agttttggaa actgcatgta gtaacaagat agaaccatca tgtagattat
    45841 ccattatttt ttgcgttgct tcttcatgtg atggttgttt atcagtatcc cagtctctgt
    45901 atgcaaaact ccaaaataca gtcttgtatc ctaaattttt agtcattgcc aagctttttt
    45961 ctgagtattt tcccatagga ggtctaaaaa atttaaccat atctttccca gttacatctt
    46021 tatataactt ttcaacatca tataattcgt cattaaagtt ttttagattg cttgtttttg
    46081 ttggcataga tggatgggtt ttactatgat ttccaactat atgtccctca gaaaccattc
    46141 tttttactaa atctttattt tcttttatat atggagctgt aacaaaaaaa actgctttaa
    46201 cctgattttg ttttagagtg tcgagtattt ttgtagtgta tccattttca taaccttcat
    46261 caaatgtaag atatagtgtt ttttgaccat cttttgtagg tccattgtat agggcatcat
    46321 agtcagaaaa tttaaattca atgtccgtat ttacttctgg tgttttatgc ttattgtttg
    46381 gtatataaaa ccaatcaaga gtagtgttat ctaaagaaga tacatctaat ttattattat
    46441 cattattagt agtggctttt gatggtttat ctgttccgtc tgaaactatt acattggaag
    46501 tatctttacc actatctatt ttttccttat cttcttgtaa ctgtgtttcc ttattttgat
    46561 tttcgttttg attgttttgt gaatttgaac atccaacaat aaaaaaaata gaaatagaaa
    46621 gtagtgttaa ataatgcaat acttttctaa acattttgaa gctcctttct aaattaataa
    46681 taattgcata taataatgat tatatgatta attacaattg catatagtat tattataatt
    46741 ggaaattact attaataata gttatatctt taaaaataaa gtcacaatag tatgacaaag
    46801 ggtgaataat caataaattt aaaaaaaaat gaaaaaaata gttgaccata ttatgagaag
    46861 atgttattat aataaatgtg ctcaacaaga agtaacaaaa taacaagcac aaagaag
//
LOCUS       DAEOTL010000024        46750 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEOTL010000024 DAEOTL010000000
VERSION     DAEOTL010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 46750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.024"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(442..594)
                     /locus_tag="KRH82_001641"
     CDS             complement(442..594)
                     /locus_tag="KRH82_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654922.1"
                     /translation="MFEIRHIVLSFLSFISITFFNKIDKTKVKNLIDNETNDTISSDI
                     IVIAYK"
     gene            complement(961..1659)
                     /locus_tag="KRH82_001642"
     CDS             complement(961..1659)
                     /locus_tag="KRH82_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654923.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELISIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPAKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            1917..2474
                     /locus_tag="KRH82_001643"
     CDS             1917..2474
                     /locus_tag="KRH82_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654924.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQL
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            complement(2824..3186)
                     /locus_tag="KRH82_001644"
     CDS             complement(2824..3186)
                     /locus_tag="KRH82_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654925.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(3620..4429)
                     /locus_tag="KRH82_001645"
     CDS             complement(3620..4429)
                     /locus_tag="KRH82_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8654926.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISMQVI"
     gene            4521..5144
                     /locus_tag="KRH82_001646"
     CDS             4521..5144
                     /locus_tag="KRH82_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HBG8654927.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELERKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            5141..6466
                     /locus_tag="KRH82_001647"
     CDS             5141..6466
                     /locus_tag="KRH82_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8654928.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIRKQKKYHY"
     gene            6487..7026
                     /locus_tag="KRH82_001648"
     CDS             6487..7026
                     /locus_tag="KRH82_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654929.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLVIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYLMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREISFHLWKK"
     gene            7045..8436
                     /locus_tag="KRH82_001649"
     CDS             7045..8436
                     /locus_tag="KRH82_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HBG8654930.1"
                     /translation="MKRRLAGEWEPIKGVMLAWPPFLPHKYIVDLTQNYSVYMCVPNK
                     EEIEIAKYYLSKWGGNLKNLIFCIAPQGFDTPWVRDWGMHPIFDENGKLFLAGAEYKM
                     STPFVSINKPEIMFDCEHNLLTTNSYEQKEDQSQELIAKQIGLPFMKLPYALTGGNLM
                     SDGFNKLMSMHILQTENRAKGISDEEFFSMVARDTGMNEYYIFSNFADYGLQHIDCYL
                     KIIDEETLLVSRTPKEHYLYERYEKILEEVKKVETRYGRPFKIFRIDIVPFQKDSDEL
                     TAYVNSVILNSRVYVPMYGIEQDKIAIKQWQNALPGYEIKGYEFDFEKEPDIIKNRTG
                     YVRTGWGNEDVIHCRTRAIWDENMLYISVKRLEEIVSENDALEVTIQIVDYSKAGLDY
                     ENCRLFYRYYGFQTWESIRLEETTEAEIFFANMIGKSGDMIEYFVQAKSCSGMCETMP
                     PVAPKGTYKVTIK"
     gene            8451..9542
                     /gene="ytvI"
                     /locus_tag="KRH82_001650"
     CDS             8451..9542
                     /gene="ytvI"
                     /locus_tag="KRH82_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBG8654931.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFAIINISYAGIIALFIALLDILPVLGTGSILI
                     PWGIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGILLLIAFLKKLNDKEIIHILH"
     misc_binding    9846..10059
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10313..11347
                     /locus_tag="KRH82_001651"
     CDS             10313..11347
                     /locus_tag="KRH82_001651"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBG8654932.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVRAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKIASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     gene            11388..12605
                     /gene="argJ"
                     /locus_tag="KRH82_001652"
     CDS             11388..12605
                     /gene="argJ"
                     /locus_tag="KRH82_001652"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBG8654933.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEAHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            12620..13480
                     /gene="argB"
                     /locus_tag="KRH82_001653"
     CDS             12620..13480
                     /gene="argB"
                     /locus_tag="KRH82_001653"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBG8654934.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            13510..14697
                     /locus_tag="KRH82_001654"
     CDS             13510..14697
                     /locus_tag="KRH82_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBG8654935.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLQIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            14806..15828
                     /gene="argF"
                     /locus_tag="KRH82_001655"
     CDS             14806..15828
                     /gene="argF"
                     /locus_tag="KRH82_001655"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBG8654936.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            15955..16572
                     /locus_tag="KRH82_001656"
     CDS             15955..16572
                     /locus_tag="KRH82_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBG8654937.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(16792..17490)
                     /locus_tag="KRH82_001657"
     CDS             complement(16792..17490)
                     /locus_tag="KRH82_001657"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBG8654938.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHELMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(17652..18869)
                     /locus_tag="KRH82_001658"
     CDS             complement(17652..18869)
                     /locus_tag="KRH82_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBG8654939.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTADLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            complement(19060..19473)
                     /locus_tag="KRH82_001659"
     CDS             complement(19060..19473)
                     /locus_tag="KRH82_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8654940.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            complement(19965..20603)
                     /locus_tag="KRH82_001660"
     CDS             complement(19965..20603)
                     /locus_tag="KRH82_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBG8654941.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGIERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            complement(20603..21466)
                     /locus_tag="KRH82_001661"
     CDS             complement(20603..21466)
                     /locus_tag="KRH82_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654942.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            complement(21463..21837)
                     /locus_tag="KRH82_001662"
     CDS             complement(21463..21837)
                     /locus_tag="KRH82_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8654943.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            22204..22608
                     /locus_tag="KRH82_001663"
     CDS             22204..22608
                     /locus_tag="KRH82_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBG8654944.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     KDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIVYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            22625..23221
                     /locus_tag="KRH82_001664"
     CDS             22625..23221
                     /locus_tag="KRH82_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654945.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            23258..25852
                     /gene="clpB"
                     /locus_tag="KRH82_001665"
     CDS             23258..25852
                     /gene="clpB"
                     /locus_tag="KRH82_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBG8654946.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(26048..27475)
                     /locus_tag="KRH82_001666"
     CDS             complement(26048..27475)
                     /locus_tag="KRH82_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8654947.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRSFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            27617..28513
                     /locus_tag="KRH82_001667"
     CDS             27617..28513
                     /locus_tag="KRH82_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8654948.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASRVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHREVSNVILKEDMK"
     gene            29178..29318
                     /locus_tag="KRH82_001668"
     CDS             29178..29318
                     /locus_tag="KRH82_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654949.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(29315..29686)
                     /locus_tag="KRH82_001669"
     CDS             complement(29315..29686)
                     /locus_tag="KRH82_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8654950.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            30235..30492
                     /locus_tag="KRH82_001670"
     CDS             30235..30492
                     /locus_tag="KRH82_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654951.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(30602..31282)
                     /locus_tag="KRH82_001671"
     CDS             complement(30602..31282)
                     /locus_tag="KRH82_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBG8654952.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYLIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            31541..31840
                     /locus_tag="KRH82_001672"
     CDS             31541..31840
                     /locus_tag="KRH82_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654953.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            32181..33836
                     /gene="ilvD"
                     /locus_tag="KRH82_001673"
     CDS             32181..33836
                     /gene="ilvD"
                     /locus_tag="KRH82_001673"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBG8654954.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGIVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRIAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIRENIRNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            34180..34809
                     /locus_tag="KRH82_001674"
     CDS             34180..34809
                     /locus_tag="KRH82_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654955.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEYLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            34835..35647
                     /locus_tag="KRH82_001675"
     CDS             34835..35647
                     /locus_tag="KRH82_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654956.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            36161..37099
                     /locus_tag="KRH82_001676"
     CDS             36161..37099
                     /locus_tag="KRH82_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBG8654957.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKKLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNGKR"
     gene            37575..38003
                     /locus_tag="KRH82_001677"
     CDS             37575..38003
                     /locus_tag="KRH82_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBG8654958.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(38156..38362)
                     /locus_tag="KRH82_001678"
     CDS             complement(38156..38362)
                     /locus_tag="KRH82_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654959.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCFAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            38684..39340
                     /locus_tag="KRH82_001679"
     CDS             38684..39340
                     /locus_tag="KRH82_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8654960.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            39424..40503
                     /locus_tag="KRH82_001680"
     CDS             39424..40503
                     /locus_tag="KRH82_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8654961.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQEFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAIAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLRELKNTAIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCVLLEEIAPKLAK"
     gene            41776..43431
                     /locus_tag="KRH82_001681"
     CDS             41776..43431
                     /locus_tag="KRH82_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8654962.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            43490..44242
                     /locus_tag="KRH82_001682"
     CDS             43490..44242
                     /locus_tag="KRH82_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBG8654963.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNDLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(44768..44818)
                     /locus_tag="KRH82_001683"
     CDS             complement(44768..44818)
                     /locus_tag="KRH82_001683"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654964.1"
                     /translation="MTEYIYYYNNKRIKKN"
     gene            45211..45504
                     /locus_tag="KRH82_001684"
     CDS             45211..45504
                     /locus_tag="KRH82_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8654965.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            45485..46126
                     /locus_tag="KRH82_001685"
     CDS             45485..46126
                     /locus_tag="KRH82_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBG8654966.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            46370..46702
                     /locus_tag="KRH82_001686"
     CDS             46370..46702
                     /locus_tag="KRH82_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBG8654967.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
BASE COUNT        18002 a         5219 c         7578 g        15951 t
ORIGIN      
        1 aataataaat tattgatata atatataaaa ccattataat atatactaaa aataagaatg
       61 tataaggtgg taaatttata taaaaaagaa tatgagttgt aaaatattaa ataatattgt
      121 actaattgga ataattttaa ctttattata gattatttta ataccattag tactgatggt
      181 gtattttaaa attggtataa gcattacaaa tacgaatatg ccaactgtaa tatgtaatat
      241 aagtagctat atacatatgt gctgtcccat atattgtatc attgtttata ttaaaaagat
      301 tatgtaaatt ggtatcaatc aataaatcat tttcagaaga aatacctaaa aacttaaaaa
      361 atacctatat gtgtatttag ttagatttga tatttttaca tttaatttta tagtgacaat
      421 attatattat ttttatgatg tctatttata tgcaattact ataatatcag aacttatagt
      481 atcatttgtt tcattatcaa taaggttttt tactttagtt ttgtcaattt tattaaaaaa
      541 agttattgat ataaaagata agaaggataa aactatatga cggatttcaa acataagagt
      601 ggatatttat ataatagata ttttatagtt aattttatta gattttattt aatactgtaa
      661 tattaatatc acaatatatt aatagtgtat taaagattga attttgtaga taactataat
      721 ttattgagag tgataaataa aaattatata atattacaga agaaagagag ggagacaata
      781 ttatatccct cttttttcta taataactaa ttattaaaaa attattaata ctctatatac
      841 ttttaatttc tttaataata actaatttat tctttatgta gttattttaa taatgctaaa
      901 ataaaattaa ttaaataaca tttataaata atttaatcat attaataata taattatttt
      961 ttatttaact aaagtattta accattcata taatgaattt aattcttgtg gtgtgttaaa
     1021 ccaatgtttg ccattttcta taatagtaag gttgcaatta aacttttcta caaatttctc
     1081 tacaacaccg atttcagtaa gttcatcatg tttaccatat aatatttttg ctggtacatt
     1141 ccattgagtg ataggatgtt gttttacata ttgtagatat tcccatgaaa gagtatgccc
     1201 aaatgaagtt gggataatta gttcatgttt aagctgttct tctgatacat ttgcccaaag
     1261 catcatattt gaaatgagct gttgcatatc tagaattgga gatacaaaaa tacactctct
     1321 taagttctct ttttcaaagc ttaacatact aaaccatgct ccaatgctat ttgcatataa
     1381 cgaaatttga ttccagtggc actttgcata ttccataata gatattaatt ctggaacaac
     1441 atgccatggg ttaaatgaat ttttttctct tttacgttct ccatgttcag gcaaatcaac
     1501 acttaaaact tgacactcat gtggaactgc aatattagca aaagcttcag cctcctcttt
     1561 attgccacat tgtccatgta tgtaaatata taatttactt gaaggatttc cccaaaggat
     1621 tgaaggaact ccatgaattt cgaaatattt tttttccata aaaatctcct ttcagtttga
     1681 tatattagtg attgttgaat taatcaaact ataaaataat gttgtaatat agaatttaat
     1741 ataatactaa ttatattagt attaaaacta attcaattag tattatatta aattataatt
     1801 aaactgtcaa gattttataa tagtataaag aattttataa attacaataa ttgacgaaac
     1861 taattagatt agctaaacta ataaagtaat taattttaaa tgaaagaggg aaaatcatgc
     1921 gtgttagtag agaaatagtt atacaagcta catcagatat agttaataaa gatgggctta
     1981 acaaagtttc tttaaaagtt attgcagaaa agctaggaat acgtacacca tctttgtaca
     2041 atcatataga aagtctagat gatttattac ttgaagtagc tcataaagga atgagagaga
     2101 tgaatagtca aatgataaag gcggctattg gaaattttgg agatacagct ataaagtgta
     2161 taagtatagc atactttaat tttataattt ctaatcctgg tgtttatgaa acaattcagt
     2221 tggctacttg gcatggaaat aatgaaacat tagaaatctt tgatgaatat aaatccttat
     2281 tagaaaaact tattctttct tgtaatctaa atacaaagaa tacaggtgaa gtattaaact
     2341 taataatgag tgtacttcat ggttattcga ctttgcaact tgggaaatca cttttgagta
     2401 aagaagaagc tataaaaggt ttagtcgatt ctattgatac tgtgttatta ggtattcata
     2461 aaaaatatga ttaaggaggt aaataaatta ttttaactta tttattgaac acttcattac
     2521 gtgggatgta aaataaaatt ttatcatttt tatgaaagga aaatagtata tttcaagaat
     2581 atttactttc tgaattggta aaccctattt ttactgttgt tgttgataat gaaaaggtag
     2641 ctgtaaaatt ccttgataat cagacaaaag cgacacaggt atcatagtat aaattgatat
     2701 ttcataagga cagtaattgg aaaattattg gataggttat ttgattatat aaaaatgatt
     2761 atataaaaaa agaaaagacc ttagctaaca acacatatca atttatacct tgaagctgtg
     2821 gttttatttt tcaaattgtt tgcggatttc tctgtcttta cggattacag tttttgctga
     2881 ttttagcagt tcaactaaag aacggatttc atattcatca caatctgaga aaatatcttt
     2941 ggcttccttt tcaaaaatta ctttggaaga aagtacatta tcacataaga gagtatcgac
     3001 tgatacagaa agtgcattgg caatcgcaat caaggttggc aggctgactt tcgtttttcc
     3061 tgtttccacg ttgctcatat gggatggtgt catgttgata atgtttgcaa cggattcttg
     3121 tgttatacct tttttaattc ttgcaatttt aattcgctgt ccgattgctt tataatcaat
     3181 ttccatagtt tttgttctcc tttcattctt ttaaatattg taactattta cagagcataa
     3241 tataatactc tatataaatg aataatttat ataatatata tttaagaaaa aaatttgcac
     3301 tacttttaag acaactacaa aagaaatgga ggcataaagc ctacatgtta agattttata
     3361 aaaagatagt aaaaaactga ttaaatggtt aacgaaaata aaaggctatt tctgtatctg
     3421 aaattcatga ggaaatgcag tttgcattga ggaaacaaat aatagcaatg aacctgaatt
     3481 tctacaaaaa tttggaaata agataccaac tttagaagat aaaaaaggac attttaagca
     3541 aattattata gacaatacga gatattaaaa aaggcgtgta tttctcatgt gatttgagat
     3601 atacacgctt tttatatttt caaataacct gcatagaaat tttttgaatg tagttttcgg
     3661 cgttatgttc tgataaataa tcaattaaat cttcttcata aatatttcca acaatatgat
     3721 acccttgttc ttctaactga tttttcatat tttgataagt tttatataaa ctgtcataac
     3781 tcccctggtg atacataact gcataatttc cctttggttt aataaaaagg cgctcatcat
     3841 ctactttatt tttaataagg ctataataat agctctctct aaaaattccc tgttttatat
     3901 ttttttcaag aacaatttct cctacatgaa aattataatc atgtaataaa caatattgta
     3961 agtgatttcc aataccttgt aacattgttt tttcatctgt tagtacagct tcaggaattt
     4021 tagttgcaat cagatattct tcctcacaat ttacaatttc gattttttct gtgtttacat
     4081 tgagatgtat ttccattgtt gaaatgacat ttctcaacat agaacacatt ttttcaatct
     4141 tcttcacttc ttcttgaaga tccattagct ttctgtgaag tacattaaga aaggtattcg
     4201 tatctaaatc attgagatat tgttttattt cttctaaagg tgtacctgct ttttttagca
     4261 cagaaataat attaaatttt tcaaattggt caattgtata ataccgatag ccattttcat
     4321 gggtaatact cggttttaat aattcaattt catcataatg gtaaagtgta tgttttttta
     4381 ccccacacaa ttctgcaaat tcacttgtct tatataattt tttaatcatt tttaaatctc
     4441 ctattgactt tagggttacc agatacttta ggataacata gaaagctttt atattcaatg
     4501 aaatgtgagg aaaagatatt atgaaaatta ttacaattag ccgagagttt ggaagtggtg
     4561 gacgagaact tggaaaacaa cttgctgata ttttaaattt tgactactac gataaagaaa
     4621 ttatcactgc tatagctaga aagaaaaaaa ttgacgaaaa ctatgtttcc tacatattag
     4681 aaaatcatgg ttggagaaac gttcctttaa caatgtgtac ttcttttact aatattttgt
     4741 ctatgcaatc catgaagaca gatttgttaa tagaacaatc aaatgttatc aatcagattg
     4801 ccagtacagg taaggattgt gttattgttg gtagaaatgc agatatatta ttaaagaagt
     4861 accagccatt taacgttttt gtttgtgcaa atatgaactt taaaatacaa cgctgtattg
     4921 aaaaaaagtt aaacaatgaa catatttcaa aaaaagaatt agaaagaaag ataagagaga
     4981 ttgataaaaa tcgagcaaga tcaagagaat tttttacgag ctccttatgg ggaaatcaaa
     5041 cttcctatca tattatagtt aatacatctg aatggaatat aaaacatctt tcttatgcaa
     5101 ttgctaactt ttcagagtat tggtttagga ggtatgaaca atgatacagt tgtcagataa
     5161 ttttaattat aaacgcttat taaaatttac atttcctaca attattatgc tggtaataag
     5221 ttctatttat ggggttgttg atggatattt tgtttcaaat tttgtaggga aaactgcttt
     5281 tactgctgtc aattttatta tgccattttt gctaatctta gggtgtgttg gctttctttt
     5341 tggaacaggt ggtggagctt taattgctaa aacaatgggt gaaggaaaaa aagaagaagc
     5401 aaacgaacag ttttcgttac tcattgttac ttctgctggt tgtggtatta ttctagctgt
     5461 tttaggtata gtaactatgc catggattgc ttctgctatg ggagcagatg gtcaattatt
     5521 gacagatagt attctttatg gatgtgtggt aattatcgct attcctgcct atattttgca
     5581 gtgcgaattt cagtgtttat ttgcaacagc agaaaagcca aaacttggat tatatgttgc
     5641 aattatggct ggaattacaa atattgtttt agacgcatta tttatcactg tttttaaatg
     5701 gggattggta ggtgcagcac tggcaactgc aatcggtcaa tatgttggtg gtatcattcc
     5761 attactttat tttagccgac aaaacaacag tttgcttaaa tttaagaaac ctaaatttga
     5821 ttgtgatgtt ttgaaaaaga ctgttgcaaa tggttcttca gaactaatga ctaatgtttc
     5881 cacatctgtt gtgagtatgc tgtataatgc tcaattacta aaatatgctg gcgaagatgg
     5941 cgttgcatcc tatggtgttc ttctttatgt agcgttacta tttcaagctg tttttattgg
     6001 gtattctgtt ggtactgccc ctataatcag ttatcattat ggagcaaaaa attatgacga
     6061 attaaaaaat ttaagaaaaa gaagtttgat tgtaattatt tgttttgctg tatttatgtt
     6121 tataataggc gaatttttat caaaaccgat tgcttttatt tttgtgggtt acgataataa
     6181 tttaatggaa atgacattaa gagcatttat gatttactct ttttcctttt tattttctgg
     6241 ttttggtgtt tttggttcta gtttctttac tgcattaaat gacggtttaa cttctgcgct
     6301 tattgctttt atgcgtattt tagtatttca agttgtatca gtacttatat tccctatatt
     6361 ctggggagta aatgggatat ggttttctat tgttggtgct gaaatattgg caactattat
     6421 gacggctttc tttataataa gaaaacagaa aaaatatcat tattaaatca atttggaggt
     6481 atctatatga gcttaacaat acaaaaagta acttcatatt ttaaagattt agaaaaattt
     6541 gaagaactta ataacgaggc atttccagat gaagaacgta tgtctataca agaaatgctt
     6601 aatttagttc aaagtaaaaa aatagaagta tctgctttat atgataagca acaatttatt
     6661 ggtttttatg ttttggtgat tgaaaatcat ataggatata tattatttct tgcaatttcc
     6721 ccagaacaac gctctaaagg atatggtgga aaagcactgt cacttatgaa aaaacaatat
     6781 cccaattgtc aaattgttct tgatatggaa actatagagg acagtgctcc taatttacaa
     6841 caaagaattt taaggaagca attttatctt cagaatgggt tttatgaaac agaatatctc
     6901 atggagtata agggactaga aatggaagtt ttatgtaatc agaaaacctt tcaaaaaaat
     6961 gaatttgaaa cattgttgaa aaatcttaaa attagagaaa tttcatttca tttgtggaaa
     7021 aagtaagaaa gtgaggtatt agaaatgaaa agacgtttag ctggggaatg ggaaccgatt
     7081 aaaggtgtca tgcttgcatg gccacctttt cttccccata agtatattgt agatttaacg
     7141 caaaattatt ctgtatacat gtgtgtacca aataaagagg aaattgaaat tgcaaaatat
     7201 tatttaagta agtggggtgg aaatttaaaa aatttgattt tctgcattgc tccacaggga
     7261 tttgatacac catgggttcg tgattggggt atgcacccta tttttgatga aaacggaaaa
     7321 ctctttttgg ctggtgcaga atataagatg tcaacaccat ttgtatccat aaataaacca
     7381 gaaatcatgt ttgattgcga acataaccta ttaactacta actcttatga acaaaaagaa
     7441 gatcaatcac aagagttgat tgcgaaacag attggtttgc catttatgaa attaccttat
     7501 gcactaacag gcggaaatct tatgtcagat ggtttcaata aattgatgtc tatgcacatt
     7561 ttacagacag aaaatcgtgc gaaaggaatt tctgacgaag aatttttttc tatggtggca
     7621 agagatactg gaatgaatga gtattatata ttttctaatt ttgctgatta tggtttacaa
     7681 catattgact gttatttaaa aataattgat gaagaaacat tacttgtgag cagaacgcca
     7741 aaagaacact atttgtatga aagatatgaa aaaattttag aagaagtaaa aaaggtagaa
     7801 accagatatg ggcgtccatt caaaatcttt cgtatagata ttgttccgtt tcaaaaggac
     7861 agtgatgaac ttactgctta tgttaattct gtgattttaa atagtcgtgt ctatgttcca
     7921 atgtatggaa ttgaacagga taaaattgca ataaaacaat ggcagaacgc tttgcctgga
     7981 tatgaaatta aaggatatga gtttgatttt gaaaaagagc cagatattat aaaaaatcgt
     8041 acaggatatg tgagaactgg ctggggaaat gaagatgtta ttcattgcag gacaagagca
     8101 atttgggatg agaatatgct ctatatttcc gtgaaaagat tagaagaaat cgtttcagag
     8161 aatgatgctt tagaagttac tattcaaata gttgattata gtaaagctgg cttagattat
     8221 gaaaattgta gactgtttta tcgatactat ggttttcaaa catgggaaag tattaggtta
     8281 gaagaaacta cagaagcaga aatatttttt gccaatatga taggaaagtc aggtgatatg
     8341 attgaatatt ttgtgcaagc aaaaagttgt tctggaatgt gtgaaacaat gcctcctgtt
     8401 gctccaaaag gcacatataa agttactata aagtaggagg tgcattttat ttgaatgaac
     8461 aagatcatac atcataccaa aataagcaga gatttttaat aaatttctgt tatttggtag
     8521 tgatattagg cttactaatg ttattaggga aatatgcgtt ttctgtatta cttccttttg
     8581 tttttgcatt tttaatagca agtttattga ataaaccagt cttatacata agtgaaaaat
     8641 tactaataaa gcgaggtatt gtagcaacca tatctgtttt tttattcttt ttaattgcag
     8701 gaataatagt aagtgtaata ggtacatatc taatatatgg aataaaggaa atttttcatt
     8761 tcctaccaac catgtttgag gaattggtaa tacctttgac tgaaacagtt ataaaagaag
     8821 tcgaactatt ttctggttca ttcaattttt cgtttattga attaatagaa gcaaatatgc
     8881 ctgtattgat gaatgaaatg agtgttttca tagtttctct ttcaaataat atcgtatctg
     8941 gtattactga tattgtttcg tctgttccat tactatttat gaaaacaatt attacaatcg
     9001 ttgcttctat ttttatagca attgattatc caacgataaa gagatttata gtgctacaga
     9061 tacctaaaaa taaaagttat cttttagcag aagcaaaagc gtttactatt gataccatta
     9121 ttaaatgtgg tttttcttat cttttaattt ttgctatcac tttttctgaa ttatatgtcg
     9181 gttttgctat tattaatatt tcttatgctg gaataattgc tttattcatt gctcttttag
     9241 atatactacc tgttttagga actggaagta ttctaatacc ttggggtatt atcagtttat
     9301 ttttagggga ttattcaatg gcattaggaa ttgcactact atatattgtg attactatta
     9361 tcaggaatat tattgaacca aaattagttg gtaaacatat ggagttacat cctgtattgg
     9421 cattagccag tatgctaaca ggattacatt tctttggatt tattgggttg ttcggtattc
     9481 tattgttaat tgcgtttttg aaaaagttaa atgacaaaga aatcatacat atattacatt
     9541 aggaaagaat agttgtatgt atgtctcttt tatggagaaa attgtgtttt ttctaaaaaa
     9601 cgctggatga aaaataattt tgacataagg tatagctttt gaatgacttg attcaagagg
     9661 gagaactttt ttaaaatata ttacagcagg aaattcatgg tgtcctatta ctgtagatat
     9721 ttataactca atttagatac aaaatgctgg aaattaatta tatagaaaat atttccaaaa
     9781 atttaaaaat tatattgaca aagttaaaaa aataaactat catataaaac aataagaaaa
     9841 taaattgaaa tcctgtgaaa aagagagtag cataaagcta gttgatagag agctgggaat
     9901 ggtggaagcc tagtaacgaa ttttattgtg aatagagctt tggaggagat taccagaagt
     9961 aatagtatgg taattggtga atctcgcctt aagagattag agtgggtaag attatcttat
    10021 caattagagt ggtaacgcgg gtgtatattc gtctcttggt ctttgaccaa gaggcttttt
    10081 taattttaaa tgtacatttt gtagatactt tttaatttga gttttaatga ttattgtaat
    10141 tttaccaata agagtggtac cgcggaaaat cgcctcttag tatttataat gctaaggggt
    10201 tttttgtttt aattagagta ttttaatcta cgtattatca aatgattatc atatagtaaa
    10261 gtggaaagat aggattttaa gactatttga atataaaaat ggagggaaca aaatgaataa
    10321 aataaaagtt ggtattattg gtgcaactgg atatgtaggg gcagagttga ttagattatt
    10381 aatgaatcat gataaagtcg aagtgagagc gataggttca aattcgtatg ttggaaaaga
    10441 tatagttgat atatatccaa gtataggata taaaaataac atgatatgta tagaaaatga
    10501 aaaagttata gatatgtgtg atgttgtgtt tacagccctt ccacatggag ttagtgaaaa
    10561 gtttgtaata aaggcaatta aatcgaaaaa gaaagttata gatttaggtg ctgattttag
    10621 aataaaagat gaagaagtat atagtaaatg gtatggagta tcttttatag ataaaatctt
    10681 acataaaaaa gctgtatatg gattaagtga aatatacaaa gaagatataa aagatgcaga
    10741 tataattgca aatcctggat gttatccaac tagtatttct ttaccattga tgccattact
    10801 aagttctaaa ttgataaaaa ataataatat aataattgat tctaaatcag gtcttacagg
    10861 tgctggtaga gaattatcga ttagtagtca ctttacggag gttaatgaaa atatcactgc
    10921 atataaaata gggaaacaca gacatactcc agaaatagaa caaaatttaa gtgaatcctg
    10981 caaagaaaaa gtaagtgtag tttttacacc aaacttaatc ccagtaaata ggggaatctt
    11041 atcaactata tattgtacaa aagaagataa tatttctata aatgatatac ataggaaatt
    11101 aactgattat tatgaattta aagaatttat agaaattctt ccattagata agatagcttc
    11161 tttaaagaat gttagattct caaataaatg tgtaatatca ttacatgaaa atggagatac
    11221 attgataatc tgttcagcta tagataatat gattaaggga gcggcaggtc aagctataca
    11281 aaacatgaat ataatatttg gtattgaaga aaatacaggt ttaaaaaata ttgcaccatc
    11341 attttagaaa taaaaaatac taaactcata taattaggag gataaatatg gagattataa
    11401 agggtggagt tacagtttca gaaggatttt ttgcttcagg gattcactgt ggcttgagaa
    11461 aaaataaaga aaaaagagat ttagctttgg tttattcaga tgttttatgt gatgcagcag
    11521 cagtagtaac tcaaaataaa gtaaagggca atcctgttta tgttacacag gaacacatta
    11581 aaaatggaaa agcacaagct atcatagtaa atagtgctaa tgctaatacc tttaatggaa
    11641 aagaaggact tataaatgct tataaaatgg ctaaattcac cagtgataaa ttaaatatta
    11701 aagaaagtga tgttttggtt gcatctacag gtgttatagg aaagccatta aatatagatt
    11761 taatagaaga aaatatggat gaattagtga ataatctaag taaacaaggt catattggag
    11821 caagagaagc tattatgaca actgatatta taaaaaaaga aatagcagta gcaataatgt
    11881 atggagataa aaaaataact attggaggta tggcaaaagg ttctggtatg atacatccta
    11941 atatggcaac aacgttagga tttataacta cagatgcaaa tattgatgga gttttgctaa
    12001 aagaagcttt aaaaattgct gttgacaaaa gttttaatag agttagtgta gatggagata
    12061 caagtactaa tgatatggta atgattctag caaatggaaa agcaaaaaat gatagaataa
    12121 acaaaaaaga tgaacattat caagtatttt tgagtgcact tacatatgtc tgtatagaac
    12181 ttgctaaact tgttgcaaaa gatggagaag gatgtacaaa actaattgaa tgctatataa
    12241 atggagcatt aagtgaagca catgcagtaa aattagcaaa aacagttata tcttcttcat
    12301 tagtaaagac agctgtattt ggagctgacg caaattgggg tagaatactg tgtgctttag
    12361 gttatgcagg tgaagaaata gatatggaaa aagttgatat tatttttgag agtatgaaag
    12421 gatatattga agtatgtaaa aatggaaatg gattagattt taatgaggaa aaagcaaaaa
    12481 aaatccttga agatgacgaa ataagtatat tagtagattt aaatatgggc aatgccagag
    12541 gaaatgcatg gggatgtgat ttaagctatg attatgtaag aataaatgga agttatagaa
    12601 attaggagga tatactttaa tgattaatat agaaaaagca aatacactta tagaagcttt
    12661 accatatata gaaaaacatc agggaaagac tattgtagtt aagtatggtg gaagtgcaat
    12721 gaaaaaagat ggtctaaaag aatctgttat ggaagacctt gtgttaatga gttatgttgg
    12781 aatcaatata gttttagtac atggtggagg ggcagaaatc aataagatgc tagcaaaagt
    12841 ggatatagaa agtaaatttg taaatggtct tagatataca gatgaagaga ccatggaaat
    12901 tgtaaaaatg gtacttgctg gaaaggttaa taaagaccta gtaaataaaa tacatacaaa
    12961 aggtggaaaa gcagtagggc tttgtggaat agataataat atgattttat gtgacccata
    13021 taaaaattat gaacttggat ttgtaggaga aatcaaaaaa gtaaatgttg agcttataga
    13081 atcttgtcta aagtcaggtt atatttcagt aattgcaact ataggtgttg gagatgatgg
    13141 agagacttat aatataaatg gtgacacagc agcttctgct atagctaaag agttaaatgc
    13201 agataaattg atacttctta cagatgtacc tggtttgtta agagagccag atgaagaaaa
    13261 atcattaata acagaagtta tattagagga tgttgataaa ttatttgaag aaggtataat
    13321 tactggaggt atgataccta aaatagaggg atgcgtagat gccttaaata acggagtaaa
    13381 tagggtacat attttggatg gaagagttcc acattctata ataacagagc tatttactga
    13441 tagtggaata ggtacattaa taagaaaaga aaatgaataa aattataagt ttaagagggg
    13501 agaataagaa tgaataacga caatacaatt tcaaaatgga atgaatattt tatagataca
    13561 tataaccaac ccaattttgt catagattat ggtgaaggaa gttgtttttt tgatactaat
    13621 ggcaataaat acatagattt tacaagtgga tatggagtat cttctcttgg gtatagtaat
    13681 agtaatttaa agaatgctct aaaagagcaa gtagataaat tattacatac ttcaaattta
    13741 tattttaatg agccagtgtt gtattcagga gagaaaataa ttaattcaag tggaatggct
    13801 aaagtatatt tttgtaattc tggaacagaa gcaaatgaaa cagcattcaa aatagcaaga
    13861 aagtatagta gtgacaaata tggtaatggt agaggaacta tcataagttt aaaagactct
    13921 tttcatggta gaacaatgat gtctttaatg gcaactggta tggacaaata ccataagtat
    13981 ttttatcctc ttcccgaagg ttttaaatat atagaaagaa ataatattga agatttaaaa
    14041 aataatcttg attccacagt ttgtgcaata attcttgaag cgattcaagg cgaaggtgga
    14101 gttaatgttc ttgaaaaaga ttatgttttg caaatagtaa aaatatgtca agaaaaggat
    14161 attgtagtga tttttgatga agtccaatgc ggtataggaa gaactggtaa actttttggc
    14221 tatgaatatt ttgatgtaaa accagatata gttaccgtag caaaagggtt gggagcagga
    14281 ataccagtag gaggagtatt ggtaaataaa aaactttcaa aagtactagg aaaaggagac
    14341 caaggtacaa cttttggagg taatttatta gctatggtgg cagcttcagt tgtattagat
    14401 gagatatcta aagatggttt ttataatgaa gtattagaaa aaggaaatta tataagaaaa
    14461 tctattgaaa gttttaataa caaagttgta ttaaagacaa aaggtattgg tctaatgata
    14521 ggaattgaaa ctaatattga atctagtatt atagaagaga aagctagaaa aaaaggattg
    14581 cttattttga ctgctggaaa aaatgtattg agatttttac caccattaac aatcagttat
    14641 aaggaaatag atgaggctct tgaaatccta aaagatatat tactagaaat taactaaata
    14701 ttcaagaaat agttgattaa agataaaaat tagaagtaaa taaaaaagta aagtgctaac
    14761 aagtttaatt gaatttaaaa agtttataag aaggggcgaa ttaatatgaa taatataagt
    14821 ttaaaaggta agagtttttt gacattaaag gattttacaa aagaagagat tagatattta
    14881 ttaactttat caagttattt aaaaactaag aaaaaagttg gtataaaagg cgatttgcta
    14941 caaggaaaaa atatagcttt attatttgag aaaacatcaa caagaactag atgttcattt
    15001 gaagtagcag ctcatgatga aggagcacat gtaacttatc taggtccaaa tgattgtcat
    15061 atgggtaaaa aagagtctgt atcagataca gcaaaagttc taggaagatt ctatgatgga
    15121 atagaattta gaggctttaa acaagaaaca gttgaaagtc tagcaaaata ttctggtgta
    15181 cctgtttgga atggacttac agatgaatat catccaacac aaatactggc agatttttta
    15241 acagtaattg aaaatgtaga taaagatttg aataaagtta aatttgtata tgttggtgat
    15301 gctagaaata atatgggaaa ctcactgatg ataggatgtg ctaaaatggg aatacatttc
    15361 gtagcactag cacctaagga actttggcca aatgaagaat tggttaagga aatgaaggaa
    15421 atagccaaga aatccaaagg agatataatg ttgactgaaa atattgatga tgttaaaggt
    15481 gcagatgtta tatatacaga tgtatgggtt tctatgggag aagaggagca atatgaagca
    15541 agaataaatc aacttaaaga ttatcaagta aatatggata tgataaagaa aactgaaaat
    15601 gaaaatgtta tatttttaca ctgtcttcca gcatttcatg atttagaaac taaggttgct
    15661 caggagattt atgaaaagtt cggattatca gaattagagg ttacaaacga ggtatttaat
    15721 tcaaaatatt caaaagtatt tgaagaagct gaaaatagaa tgcatacaat aaaagctgtt
    15781 atggtttcta ctatgactga tgtaaatatg aacaataatt taatatagat atgttttaat
    15841 atagacttta ctttaatgaa aatttataaa atattttaaa tatattattc aaaaactctc
    15901 attatatgtt aaaataactt atgtatcaac aaattaagag ggaggatttg agatatgaaa
    15961 aaaatcatat tagctttaac aactttttta ttagcaatat ctttaacagc atgttcaagt
    16021 gcaaaaccag aagatacaat tgatagtttt tttaacagtg cgaaaaagtt tgactttgaa
    16081 ggcatgaata aggtaatgga aaataatgac gaaaaatata aggatatatt aaaggaatta
    16141 gatacaaaag acccaaatgc ccaatatgtt ttagattatc taaaacagaa tgcatctaaa
    16201 atcacatata caataaaaga cagcgaggtt aaaggtgata aggctacaat caaagtagaa
    16261 tgtaaattta tagattcaac accattactt caagaaatag tagctgaggc atttacaaag
    16321 atgattggta tgagtttttc aggacaagac ttaactgatg agaaaacaac tgaaatgtta
    16381 gtatcaatta tgaaagaaaa acaaaaaagc gttaaagaga cttatgttac aaaaaatgta
    16441 gagtttgaat gttctaaaaa ggataataaa tggataataa gttcagtaaa tgatgcagta
    16501 gctgatgtat tgttatctaa tcttgttaca gcaggacaag aattttctaa ctctatgaat
    16561 acacttgaat aatattgttt aggtgtagta aagtaataaa tatatgatta tttttataaa
    16621 taaacatata aatatttatg aaggatacca tttttggtat cctttttatt aatataatga
    16681 aatacatggt taatttctat attgtcaaga aactatgata tatgttataa gtctatacta
    16741 tttaaaataa acttataaca tatatttttt ataatatagt gcatgaaaaa tttatttaac
    16801 taattttaga tatttattga caactgattc agccaagcat tttgatgaat caacaatatt
    16861 tattgaagga tatgattttt ctaaaactac atttaaatca gtacaagcaa ttactatatt
    16921 ttctatagat tcatttttaa catcttcaat aagtttattc caaatatcaa tattgtgtgg
    16981 attttcttta tccattttta tattttgaat aagattgttt aattttattt gccattcatc
    17041 tttaaatata aattcatgtc cattatgtat tataccattc tggtaaattg tagactcaaa
    17101 agttgaacta gtcgaaaaaa gagttacttt ttgtgagata gtaggtaatt ttttaactgt
    17161 ttcttctaca atatttaata ttggtatatt aatagactct tttaattctt taaagtatat
    17221 atgtgctgaa ttgcatggca ttgcaataaa atttacacca gttgattcaa gcttttgtaa
    17281 tccatcaatt atagtttctt tcataagttc atgatttatt ggacggtcaa tataaaatgg
    17341 ggtaggtaat gaatatatca tcatctttgg aaattcatca tcatattttg ctccatattg
    17401 agattgacac tcatcaataa ttaaatcaac aaaaggggct gttgaccttg gacccattcc
    17461 agccaaaata ccaattaatt tttcattcat aaaaattatc tcctttatat ataaatatat
    17521 ttatgtataa aataaaaatc tataaaagca taaaattata ttttataata gattatattg
    17581 tacacttata taatataaat ataaagtgat tttttagatt atatatttta atatactttc
    17641 ttatataaga attattttaa atcaagatta tctagtattt ttaaaaatat ttttacagca
    17701 gtatccaagt catctacaga aacactttca ttaggattat gacttacgcc cccagcgcat
    17761 cttataaata ccataccaat atcagttata ttatccattt cctgagcatc atggccagca
    17821 ccactataaa tataaaaagg attaagattt aaatctataa aacttttttc tatgattttt
    17881 gttattttat tagaacatgg tacaggaaca ttttcaaaag caagttcact tgtataatta
    17941 agttttctat tttcacatat atgtgatatt tcattaaata tcttttctac agaattatca
    18001 agaatttctt gtgaacaaga acgtacatcg agtgtaaatt cagctctttc aggtaccaca
    18061 tttgatgaag atggatagaa attcatcttt cctacagtag caaccaaatc agcagtcgtt
    18121 ttagctactt tttcgatagc taatacacat tcacaggcac aacatccagc atcaagtctc
    18181 atattcattg gaagtgtacc agcatgtcca gacttaccat ttactgatat cttaaaactt
    18241 ttaaatcctg taatacttga tacaattcca gcaggaagag attcattttc taaaacagga
    18301 ccctgctcaa tatgaaattc taaatatgca tctacatctt ttctaggatg caaatttgtt
    18361 aagttttttg tattaaatcc aaactttgtt acagcttctt caagtgtaat tccattttca
    18421 tcaacagatt taagaagttc ctctttaaaa gtaccagcaa aaactttact tcccattaaa
    18481 gaagtttcaa atctagttcc ttcctcttca gcgaaagcaa ttagcttaat attgaaagga
    18541 taagacctat tattgtgttt tgcttcttca agaccaacta gaggcactat tatacctaac
    18601 ataccatcaa atatacctcc acactttaca ctatcttgat gagatgcaac tactaatgtg
    18661 ggagcatttg gaaagcttga tttatatgta cctataacgt ttccaatgtc atcaatttca
    18721 atatcaagat ttaaaccttc catccatgaa ctaattaaat caatagattt tttatgttct
    18781 tgagtcaaga taagtcttgt aagaccattt gttgttgaac ttatttttcc taatgtttgt
    18841 agataatcca tacatttttt tcctaacata tttacctcct aaaaatataa tttttattta
    18901 agctaagatt agcttttata cttataattt ttgaactttc aaataatttt gtatgtatag
    18961 taaaatacta ttttagtatt aataatgata taaaaatata aagtctgtag acgaagaaca
    19021 gaagttttaa gttaaaaata tgaaatatga tttttattat tatagtattt ttctataata
    19081 atatctcttt ccagttagag gataattttc aagtgaaaat actttatggt atccaaattt
    19141 ctcataaaat ttaggtgctt gaaaactgaa tgtatctaaa aaaacatatt tacaacctcg
    19201 ttctttagca attttttcag ccttatataa aagctgactt ccagtacctt tatatctaag
    19261 cttctcacta acccataagt attttataga aagccaatta ccatgagtaa cacctataaa
    19321 acctgcaaca attttacctg ctttatctcg aatatatatt cctaaatcca ctgggttttt
    19381 atcttcaagt ctagcaagat tatattttaa taatccttga aaaatagtat cttcatcttg
    19441 tttttctatt ttttctgtaa tttctaattc catatttgaa ctttctcctt gtataatctt
    19501 ttgtatattg gtatttttta ataaaatcag tagaaagaat atagtttaac attattctaa
    19561 taggcattta tgctaatgtc aaactaataa tacttattct taattttata ttattgatat
    19621 taaatttttt taaataaaaa tgtagtttaa gttatataaa aagaaatcat caataaattt
    19681 agtaaaccta aattgttgaa tattaaaata agttaattta atacataaaa actattttag
    19741 atgttattct attgctatgt tcaataatat cattagtagt tcaatttata aaatgaataa
    19801 attatataaa taagattaga aagtagtaaa tagtcttatt aaatataagt aataaaataa
    19861 taaataccta gtagagatta atagttgaaa aataaaatac taccaaaata aactcgatag
    19921 tattttattt aaatacttaa atacagaaat atatatagta tattttatac ttctttttta
    19981 ctatagattt ttgatgatat aaaatatgaa atcacaaata gtaaaatagc aacaaatgga
    20041 agagaatata ctagtgtatt aagtataatt tctatagaaa taggtgaact aatattttct
    20101 aaaatacttt taaaaactaa taaagctagt gttggaacta aaaagcataa aatcattaat
    20161 aaacgagctc tttctatacc aaatttataa ataagtggta gaataaggct accaaaacat
    20221 actgaaattg ataagattag tgcattaata agtagtgttt catttaatat aagtgtattt
    20281 ttaaaataac caatagttac actaacaata agtgaaacaa gaacacctat aaagctaaat
    20341 attaacatag ttaaatattt acttaataca atatcattgc gattaatagg cattgtaagt
    20401 acataactat cccatttatt caaatcatca tatgaaaatg ttgaaacaat cattgtagta
    20461 cataaaacta taataacacc tataaagtta ttaacatttc catctcctaa agaagacata
    20521 aagccaaaca taatgatgaa taaaagtata aactttatat ttcctttcaa attaagtaaa
    20581 tcttttaaaa ttagaccttt cattatttat cacctctcac ataaaataac ataatttctt
    20641 ctatagacgt attatcaaca atacagtttg gatgtcttga gataaatcta tgtttatctt
    20701 taagaagtac ttcatatcca aattggcttt tacgataata tgaataatcc tctcttgaaa
    20761 ggttatcaaa atcactaggt ttacatttta aaactcccat agtatcaatt aattcatcct
    20821 tattttcact aaatacaatt tttcctttat gtataaatgt aatatagtct gctatcttat
    20881 ctaaatcact tgtaatatgt gaagataaga taatagagtg ttcttcatct tgtataaaat
    20941 ctaaaaatat atctagtatt tcttcacgaa cgatagggtc aagtgaacta gttgcctcat
    21001 ctagtattaa taattttggt ttatgagata aggctacagc aatactaagt ttcatcttat
    21061 tcccctttga aaactcctta attaatttat tgtctggtac tctcaatttt tttaagtagt
    21121 ctttaaataa ggtgtcattc caatttttat agattttact catgattttt gaaacatggt
    21181 cagtgtttaa attttcatga aagttgcttc cctcaaatac aaccccaatt tgctctttaa
    21241 tttctttttc atttttttta ctatcaagac caaagatttc tatatttcca ctatcataag
    21301 atattaaatt taaaattgct tttaatgtag ttgtttttcc tgcaccattt tcacctacaa
    21361 atcccattac actccctttt ggtactgaaa aagatatatc ttgtaggcta aaatctttat
    21421 aagttttatt taaatttttt atagttattg catccatact tatcattctc ctttatataa
    21481 taaaaataaa atatctttta attcgtcata tgtaatatca ctactttttg ctgtatcaac
    21541 tgctttttgt aggtattctt caattaaacg aaattgttct tctttgacaa aatccatgtt
    21601 tttactagat acaaaactgc ctttaccagt aactgtctca ataaatccgt ctcgttctaa
    21661 atcgctatat gctcgttttg tagtaattac acttattcta agttcttttg ccaatagtct
    21721 catacttgga agagctgagc cttctggtaa ctctccactt ataatcatac ttttaatttg
    21781 tgtagtaatc tgttcatata ttggcttccc actcgaatta ctaataacta tattcaataa
    21841 gacacctcct taaattgtat atatagtata tacacattat ataaatatat atataatatg
    21901 tcaactgatt ttagaaaaaa ctaattgcca atattataca tttaataaat gtaatgtatt
    21961 ttatgaaagt ctgccatatt aaatagattt aaattttttt aaaaaattta taaatattgt
    22021 tcaaaaatcc tgccaataaa ttggaaatac taaattaaaa aaataataaa gtttagctta
    22081 tagctaaata aaagtttgct tataaggtga actttttgca tttttagttt tgacatacat
    22141 atttttttgt aatatattta tattatcaat tagagataag gagagtgaga agagatattt
    22201 aatttggata agacattaaa aaaggattta aatcaggaat atacagagag caaaagttta
    22261 gttatgaata aaagtaagta tatgaatgtt tgttttaaga attatattaa agtagtagaa
    22321 ggaatgtata ctaagaagga tttaattcca ttaaaattaa taaactctat ggataaaaat
    22381 aataagatta gaaaaacatt atatgaatta tcttgtgaat ttgaatatcc aaaaacttct
    22441 ttatcttcat tgtttacgga gctgaaaaaa atggattttt tacaaagagt gaaaaatggt
    22501 gagtatatga taaatccaca tatagtatat aaaggtagta gagctgataa agaaagttta
    22561 ttagcagaat ataatcagat aaaaagacct aataaggtta gtaaataagg aagaaggttt
    22621 ttatatgagt ttaaaacttg atagaaatgt tctacagtgg tttgactatg tatttgagaa
    22681 tgaaaaaact agtttgagac actataattt taattgtaca ctaaaggaga ttagttctac
    22741 cagtttgaac aaagtagctt ttattttaga aaaaaataac tctaagtact ggaagcttta
    22801 ttttgaaata ccagctgaag ttactttaaa acttaagcaa aacattcatc ctttatttag
    22861 ggaatatata tacgaacaaa tatcactgta taacaataat caaatttaca attttgtaaa
    22921 ttcaaacata ttaaaagtgt ttaataatat tgctatttat caatataata ttttagaaaa
    22981 tctatacact attgatttta aaaagagttt tatagataaa tgtcagtatt tattaatagg
    23041 tgaaaaaaga cttatagatg aagacttgta tttaatagca aaatcaaaag aagtattcga
    23101 tttttttaat tcagatggaa catttaattt aacattgagt ttcgatatac aaaaaaacga
    23161 gaatttactt gatagtcttt tagagcttag aaaatcaata attataaatg agagaattta
    23221 atttatttgg atataatatt aaaatggagg gatttatatg gacgtagaaa aaatgacttt
    23281 aagagttcaa aaaagtttaa atgaggctta taacgaagca gtaaaaaatc ataaccaaca
    23341 agtagatgta attcatcttt tctcagcact tattaatcaa gaggatggat tgataccaaa
    23401 tataatcgaa aaaatgaata tatcaattga ttctttgaga aatactgtaa actttgaaat
    23461 tgataagctt ccaaaagtat atggagaagg tgctgactca caaggagtat cagctactag
    23521 aaaaataaat gaggtgctta taaaggcaga gagtatttct aaagaattta aagattcata
    23581 tataagtgta gagcatgtta tgcttgcaat gatggaaaca gaatcaaaat cagctgttgg
    23641 taaaatatta aaacaatata atataaataa gaatgacttt ttaaatattt tatcacaagt
    23701 gagaggtagt caaagagtag aaacacaaga cccagaaggc acatatgatg cacttgctag
    23761 atatggaaca aatttagtag atttagccaa gaaaaataaa ttagaccctg taattgggag
    23821 agatgaagaa ataagaagga ttataagaat tttatcaaga agaacaaaaa ataatcctgt
    23881 attgattggt gagccaggtg taggtaaaac tgcaattgta gaagggttag cagagagaat
    23941 agtaagagga gatgtcccag aaggtttaaa agataagatt gtattctcac ttgatatggg
    24001 agctttaatt gctggtgcaa aatatagagg tgaatttgaa gaaagattaa aggcagtttt
    24061 aaaagaagtt caaagttctg atggaaaaat tatactgttt atagatgaga ttcatactat
    24121 tgttggagct ggtaaaacag aaggttcaat ggatgcaggt aatcttatta aacctatgct
    24181 tgcaagaggt gaattgaact gtattggtgc aactactttt gatgaatata gaaagtatat
    24241 agaaaaagat aaggctcttg aaagacgttt tcagcctgta attgcagaag aacctactgt
    24301 tgaagataca atatctatac ttagaggttt aaaagaaaga tttgagatac atcatggagt
    24361 aagaatacat gataatgcta ttgtagcagc agcaaaactt tctcatagat atatacaaga
    24421 tagattttta ccagataaag caattgattt aattgatgaa gctggagcta tgattcgtag
    24481 tgaaatagat tcattgccaa cagaattaga tgttgttaga agaaagttat ttacattaga
    24541 aactgaaaga gaagcattac ttaaagaaaa tgatgataaa agtaaatcaa gattggatga
    24601 tattcaaaaa gaaatagcag agttaaaatc taaaaatgat gaaatgacag caaaatatga
    24661 aaaagaaaag agtcaaatat tagatattaa aaacttaaag gctcaattag acgaagctaa
    24721 aggtaaagct gaaaagtatg aaagagaata tgatttcaac aaagcagcag aggttaaata
    24781 tggtgaaata cctaagttag aagaacaaat aaagcagtac gaagaaaata tgaatgatgg
    24841 ttctgaaaat tctcttttaa aagaagaagt tactgaagaa gaaatatcta gcattgtatc
    24901 aaaatggaca ggtataccag taactaaact agttgaagga gaaagagaaa aattacttaa
    24961 actagaagat gaacttcata aaagagttat tggacaagat gaagcagtta cagcagtttc
    25021 aaatgcagta atacgtgcaa gagcaggatt aaaagatgaa agaaaaccaa ttggttcatt
    25081 tattttctta ggccctacag gtgttggtaa aactgaactt gcaaaaactc ttgctagaaa
    25141 tttattcgat agtgaagata atataataag aatagatatg tctgaataca tggaaaaaca
    25201 tgctgtatca agactagttg gacctcctcc agggtacgtg ggatatgaag agggtggtca
    25261 acttacagaa gcagttagac gtgctcctta ttctgtaata ctatttgatg agatagaaaa
    25321 agcacatgag gatgtattta acatgttctt acagatatta gatgatggta gacttactga
    25381 taataaaggt aagacagtag actttaaaaa tactcttata ataatgactt ctaatatagg
    25441 aagtaattat ctattagaag caggaggaaa tataacagag actactaaca atttagtaat
    25501 gaatgaaatg aagcatagat ttaaacctga gtttttaaac agagtagatg atattataat
    25561 gtttaagcct ttagaccaag aaaatatcaa gaaaattata gatatattta tgaaagattt
    25621 aaaaaataga ttaaaagaaa aagatattac tattgaagtt acaaattcag caaaagatgt
    25681 tatggtgaga gaaggatatg accctgtata tggagcaaga cctcttaaga gatatatagg
    25741 aaatacatta gaaactataa ttgcaaagaa acttattgct ggagatgtgt ataatggatg
    25801 tactatagtt atagatggaa aagatgaaaa tattgaagtt ttagttaaat aataaaggaa
    25861 tcagttgagc ataatatact aaatattttg ctcagctgat ttttatttat aaactatagg
    25921 aaaagaaata ttttatcaaa ttaataaaac atttttaagt caatatgtcc aaattaaatt
    25981 taactcaaag gaagtatttt agtaaatttc ttataatata atcataattt gaatataatt
    26041 ataaaaacta ttgttcattt ttattatatt taaataaata aaagccaatt aatattgcac
    26101 ctattaagca aacaagtgta acaataatat aaacatttct cattccaaat acaaatattt
    26161 tatcattatt aatcacataa tcattgaccc tatatccagc tttaatactc ataaaattat
    26221 ataaaagtgt tgtagaaata gtaataccta taacttgtcc taaatttctt acaagggaat
    26281 ttatgcttcc tacaactcct agcttacttc tagaacagct tgacattatc aaagcattgt
    26341 tagcaggttg aaatatagct tgtcctattg atattatcga tatataaatt acaaataaaa
    26401 taagggcaga actttctttc aatcttgaca ttagaaagaa tccaaaactc ataacgagaa
    26461 gaccaattaa aataattttt tctgacttaa ttttatctga tatattccca aatataggtg
    26521 aaaaaatggc taaaatcaaa ggtgatagta tcataaataa acctgcttga atagggggaa
    26581 gtttcatagt actttgtaaa taaaatggaa ttaaaatact tgatgatgca atacaaatga
    26641 atgatgtaag agcacaaatt aaattcaatg aaaatttaaa acttctaaaa atttcaaggt
    26701 caagaagcgg ttgaggatgt tttttttcta atatcaaaaa taatataata aaaataattg
    26761 ataataatag tgcaattaat atatatggat ttagtaatcc tgtttgttga gcactaatta
    26821 gagcactaaa aaataatgtt gttcctaaaa attgaagtat agcaccagtt ttatccatat
    26881 tttctgaaga ttttttacta ttaggaagaa attttgtatt taaaaagatt acaataagac
    26941 cgattggaat atttataaaa aatataacat tccaatcaaa tattgacaaa ataaatcctc
    27001 ccacagatgg tccaaccata tttccaatag caactgcagt aactaaaatc cctagggctt
    27061 ttcctctgct ttcttttgga aatagttctg tgataattcc atgattgttt gccatgtagg
    27121 cagaagcgcc tattccttga ataaagcggc aaactataag taaagttaaa gaattactta
    27181 atccacatag taatgaagct gatgtaaaga gaatagtacc tacttgaaat actcttgatt
    27241 taccaataat atctccaagt cttccaaaaa ataatagtgt tgaacaaata ataattgagt
    27301 aacttgctat tacccattca atagatgcta gagatacatt tagtttgctt gcaagaactg
    27361 ggagagcaac atttataata ctagaatcta atgttgccat aaaagtcatg gcaatgacta
    27421 caaataaaac tgtgattttt tttctattat catctttttt aaaagagttt gtcattttta
    27481 ttacctcctt attataatga ctggcattat gttaatgttt acaatgatag ttacatttta
    27541 tataatagcg atatgaaata atgaatacaa taactatatt gcttataatt agcactattt
    27601 tgatgaaggg ggaataatga aggataaaaa tacatatttt aacaggaaag gtcaagaaaa
    27661 ctttatagat atttttttaa aggatgacat taaaaaagga gcaaacttta aaagacattg
    27721 gcatgagcat ctacaaatat attattttat tgatggtata gcatatcttg aatgtggatt
    27781 ggataatttt aaggtagtgc ctggaaatat tgtaatagca aacagtaatg aattacatta
    27841 tttagaaagc ttatcagata atttaaaatt ctatagtatt cgtattgaac ccacattcct
    27901 ttttagtaat caagttgatt tgttacaaac caagtactta gcaccattgg ctttaaatca
    27961 tattgtattt aataatttaa ttcaaaatga ttctctgatt ttaaaatgta ttacaactat
    28021 acttgatgaa tatcacaata aagaagttgg atatgagtta tctataaaag ctaatatcta
    28081 tcaattaata gtactcttat taagaagtca tattgataaa atatattctg aagatgaatt
    28141 tataaaaaga aagtattctt tggaaaaatt tgaatgtatc tttgatttga tagaagaaaa
    28201 atatatggat aaaattacat taaaagaact tgctagtcgt gtgaacttga gtgcacatca
    28261 cttttgtaga acatttaagc aaataacagg taagactaca atcgatttta taaatggaat
    28321 caggcttgat aaagctatat attatttaaa ggaaacagat ttaaatatga cagaaattgc
    28381 tatgagatgt ggctttgata gcataaatta ttttagtcgc ttatttaaaa ggaattataa
    28441 tatatctcca actaagtata gaaatgaaca tagagaagtt agtaatgtta ttttaaaaga
    28501 agatatgaaa taattcataa atatacttta tagaaaatat atatttttaa atctttgagt
    28561 ttttcttaat aaatattaat aaagtatagt acataaatga gtaagactac ttgtatagtt
    28621 aaatgtgaaa atgagtatga aagaatgcag tgtctatgaa aagtatattt taatatgaaa
    28681 ctaaaactgg aaaaataaga atagcagaaa aaatgattat attataaatc aatttttttg
    28741 agacatctgg cttagattct gaaagatatt taatcaaaga aataaaacta ttaaataagc
    28801 aagtaaacag ctaaaatagt atgattttta tagaaaattt aaatccatcc taaagaatta
    28861 aaagaaagtc aaataaatat aaaaaaatta tatatttata aaaaatttta taataaaaat
    28921 catcctgaaa aatatataaa aatagaaaaa acatacaaga ttctacaata atagattttt
    28981 ttgttattat tacgagtttt ttattgcaac tgtagaataa aagtattatt atataattaa
    29041 gataattatc tagggaaatt ttggataatc aaaatatatt ttataaaatc aaaatacaat
    29101 tacataaact ttattaaaaa tttgttggga atttctgact aacattaaga acgtaagttt
    29161 gttgggggat ggtatatgtg gaaaagtcaa acactactgt tacaaaaaaa gaaaaaattg
    29221 aagatatagg aatgaaatta gaacatttat tgagtgaaga tattactttt tatgaattat
    29281 tacttgagat tttgtataaa gaaaaagaag agaattaatt ctcttcttta aggaatcttt
    29341 ttaaataggc attatcaatc attttttcta tagcttctct atcttctttt tcaagagaat
    29401 atattttttc taagagcttt tttgtttttt cacttactga taagttctct atgattaatt
    29461 tatcttcttt gcttattttt gtattatcat ttacgcctaa taaataatct gttgatgttt
    29521 ctaatgcttt tgctaatcta actattattt cacttttagg ttctcttaaa ttattttcat
    29581 aacgtgacaa gctagcctca gttataccga ctttagtagc aagttctttt tgatttatat
    29641 ctaattcttt tcgtagattt gctattctat ctcctaaact ttccatatgt acatcactcc
    29701 ttaccgaaat tataagttat tttgataaaa agtaaaataa aattaccaaa aatataaaaa
    29761 aaaaaggtta aaataataaa atatattgaa aattaccatt tgtatatgta taatatgaat
    29821 tatacaaatg gtaatttgat gagaggtggt atgttgaaat aagaaactga attaattaat
    29881 aaatatatag aaagttttga aaacccttaa ttgagatata aacaatatgt acaaaatttt
    29941 ttgcaagtaa aattaccaaa tgtataaaat aaatcagtag catagataat tttatgcttt
    30001 aatacattag attatctaat ttagttataa tggtcaaaaa tgcaatctac aaataaaaca
    30061 aagtattatc aaaaaagtat tctttaagag aattttttat tagagatgta attgatataa
    30121 ataatcgtat taaaaaataa aatactaagt ttaaaaattt aaataatcta taaatcaatt
    30181 ataaaatatt atttcttaga aattaaaatg aattaagtaa atggaggaat tgatatgata
    30241 ataattagaa gtcaagataa aactaattta atgcagataa accaaattaa aatagatggt
    30301 agtcaagttt atgcagtatt tgaaagtaaa attgatactg taaaaatagg agattatgaa
    30361 aataatacaa gagctataca agtgttggac aatatacaaa acttcattga aaatggaaca
    30421 aaatatgatt atataacatc aaataaagtc agatacaatg ttaataaaat atttcagatg
    30481 ccagctaaat agtgagtgtg cattttaatt taataactaa agcccacttt cttttgtagt
    30541 atgaaagagg gctttacata tttgtaaata tcgaagtaca cttgttttat caataaatta
    30601 tttaataagg tataatggac caattaaaca ataaaaattc tcctaaaaca gcaagtatta
    30661 aatatataat agcttcattt ttgtaaagag aggtaatttt ttcgcttatg tcatcatcaa
    30721 ttgtaatagc aatttcatct tgaataatat ttttatatat agatgggaaa atatcttttt
    30781 tctttataag attaaataaa ttatttacac ctacccatat caaatatcct aaaacagcac
    30841 ctaatgtgtt catcattaaa tcatcaatat ctgtagctct taagttaaac aattgacaaa
    30901 gttcaattgc taatgaaaaa cctaatccag ttaatgaaac attgataata tttctaaaat
    30961 ttttccaaat taaaggtagt aaaaatccta aaggcataaa cataattata tttaaaatat
    31021 atgttaagat gccaactgag tcaaaaggta ttagatttat ttcatcaatt ctaaaaagcc
    31081 cactatacct tcctatatcc catatgctac caattccagc tttactaagt gctagataga
    31141 tatataataa aaaaatatat acccatacta aatgtatcat tacattcttt tcaactttca
    31201 aattttttcg ttttataacg actatttggt atattaagca tggtaatata acgcaaataa
    31261 atgaataaaa tgtccatatc attttatttt gtcccctttc aaatttatgt ttttagtttt
    31321 ataagtacta tctttatatt aaactgtaag ttttaaaaat cttttaataa aatcttaaaa
    31381 atttattaat ttataaaaat atattattaa gattaaaaat atatataatc aaagtttcta
    31441 caattatata gttaggtata taaaaatttt atcgtatgta taaatattat aaatatatgg
    31501 aaataataat agtatatttt ggtaaagtag gaggaatttt atgaaatgga ttaaatggta
    31561 tagtattaca tgcatatgta tttttatagt agtagctttt tatatgttta tatttcctaa
    31621 taaaatagaa actattgata cttcatctgc atatagcttt gttgaaaaga aagtaccaaa
    31681 tagtgctgtg tatcaaggat acaaaaagaa tccagttgat ggtactacta caatttatta
    31741 cagctatgat aattcaactc atatagttag attatcacat ccagaagact attcaaggaa
    31801 gattaattgg gataaagttt caaacatcag atttgattaa tctttaatat ttataaaagt
    31861 ctatatatct aaggcaaata tattactaag gcaaatatat tattaatctt attcatagtt
    31921 gagcactttc tattatagaa gtgcttcttc tgatttatat cataaaatat tactcaacaa
    31981 tttgtaaaat atattagttt ataaaatata tttaaaagat aatattatat aatacgattg
    32041 tgtaagatat tgataaaaaa tcgtaataaa ttttcattag tatatgctaa tattttttta
    32101 caattttcgt aattaattaa tagaaaaata tattataata atattatgaa aatttaaaaa
    32161 agtaagaaag aggtaatatt atgagaagtg atataaaaaa aggaatagaa ggagctccaa
    32221 agagagcgtt aatgtatgga atgggtctta ctaaagaaga aattgaaaga ccattaatag
    32281 gtatagtaaa tgcacaaaat gaggtgattc ctggtcatct gcatcttgat gaaatagcag
    32341 aagctgcaaa aaatggagta agaatgagtg gtggtttgcc attagaattt cctgctatag
    32401 gggtatgtga tggtatagct atggggcatg taggaatgaa ttattccctg gcttcaagag
    32461 aattaatagc agattcaata gaagctatgg ctatggcaca tggttttgat gctttggtac
    32521 ttatacctaa ttgtgacaag atagtgccag gtatgttaat ggctgctgca agacttaata
    32581 taccaagtat tgttgtgagt ggagggccta tgcttccagg taaaaaaaat ggaaaagtat
    32641 atgattttaa ctctgcaatg gagggtgttg gagcatgtaa agatggaata gtaagtgaag
    32701 aagaattaga agcgttagcc atgaactctt gtcctggatg tggttcatgt tctggtcttt
    32761 tcacagcaaa tagcatgaat tgtttaacag aagctttagg catggggata ccatataatg
    32821 gtactgctgc gtcacattct ggagaaagaa aaaggatagc aaaatatgca ggtatgtatg
    32881 ttatggagtt acttaagaac gacataaaac ctagagatat tttaacaata gatgctttta
    32941 aaaatgctat agctgtggat atggcaatgg ctggttctac aaatacagta cttcacttac
    33001 ctgcaatagc ttatgaatca ggaatagagc ttaacttaga tttttttgat gaaataagtg
    33061 aaaaaactcc ttgtttaaca aaattaagtc caagtggaaa acatcatatt gaagatttac
    33121 atatggcagg aggaatacca gctataatga acgagctttc aaagataaat ggaataaatt
    33181 tagattgcaa aaccgtaaca ggcaagacta taagggaaaa tataagaaat tgtgaaatag
    33241 aaaatgaaga agtaatacat acattaaaga atccatatag taaccaaggt gggcttgcaa
    33301 tattgaaagg aaatcttgct ctaaatggag ctgttgtaaa aaagtcagca gttgcagaag
    33361 aaatgttagt tcatgaagga ccagcaagag tttttaattc agaagaagaa gctgtaaatg
    33421 ctatttttgg taaaaaaata aacaaaggtg atgttatagt tataagatat gaaggtccaa
    33481 agggtggtcc aggaatgaaa gaaatgctat ctcctacatc agcagttgca ggaatgggac
    33541 ttgataagca tgtagcactt cttactgatg gtcgtttttc aggggcaact agaggagcat
    33601 ctataggcca tatttctcca gaagctatgg aaggtggttt aatcggacta gttgaagaag
    33661 gagatataat ttctataaac ataccagaca aaaaattaga gttaaaagta gatgaagttg
    33721 aaatagaaaa tagaaaatta aaatttaaac ctttagaacc gaaaataaag catggatact
    33781 taagtagata tgctaaattg gtaacatcag caaatacagg agcagtttta aaatagtaga
    33841 ctatatttat gtaaattaga aaaagttaag aaaatattaa ttggatatct taggtgttat
    33901 atcactaatg aggtatcctt tttattttgt atgaaaaaca cagcaaaatc ttgattatct
    33961 ttgaaaacaa tacatctcta ttataaggaa tacgagtaca gcatagagat gtatctttta
    34021 gaccttgttg aggtaataca actttttaaa agtttgatgt ggaatgcttt tcattccatc
    34081 tgaactatga agaaattgaa agtcagttaa ttcttgacat aataaatatt aaaatgtata
    34141 ataaaaaaca aacagacagt ctgtttttag gagggaaata tgaatagaga agaaaaaagt
    34201 aaaaatagta aagaaaaaat tatccaatca gcattttcac tattttcgtc taaaggatat
    34261 gattcaacat ctacacaaga tattatcaat ttatctggtc tatctagagg tgcaatgtat
    34321 catcacttta aaactaaaga agatatactg agaagtgtca caaaagaact ttactcacaa
    34381 atgaataatt ttttagagta tcttgttgct gatgacaccc ttacagcaaa tgaaaaaata
    34441 atagaattgg ttgttcatag tgcgaatgat tacacacgta gaaaaatggt acattgtagc
    34501 tggttagaaa aaatcccatt cgctttaata gaggaagttc gtaatctcaa caatgtagtt
    34561 gcacccaata ttgctaagat aattaaacaa ggtgttgaaa ataaagaatt ttcttgtgaa
    34621 tatccagagg aattagctga aatgctcgtt tttagtattg atattttact tgaccctgta
    34681 ttatttaaac gtgaatacag tgaagtatgt aataggttgg attttttatt attcatgtta
    34741 aaaaaaatgg atattcctct aattgatgag tacggtattc aaaaatttaa agatttattt
    34801 aaacaatgat aataggaaaa gtgaggaata gactatgttt tataatgcaa aaagctgtca
    34861 aatgatgata ggaagtaata cagtgaatta tattgaattt ggtagtggta agaagacact
    34921 aattatttta ccaggattag gagatggttt atttccttta catggaaaaa tacaggcgat
    34981 tgcttttgct tttagatata agcaatttgc aaaagattat aaggtttatg tatttagtag
    35041 aaaaaatcaa attacagaaa aatattccac aagggatatg gctaaagacc aagcagatat
    35101 aatgaaaaaa cttggaatta tgaaagcaga agtaatgggt gtttctcaag gtggaatgat
    35161 agctcaatat ctggcaattg attatcctga gttagttgag aaacttgtgt tggcagttac
    35221 ttcttcaaag caaaatgata ctatccaaaa tgttatttgt agctggattg atatggcgaa
    35281 gaagcagaat tacaatgatt taatgattga cacagcaaag aaatcctatt ctgaaagata
    35341 tttaaaaaaa taccaattat ttattccttt tttaggaaaa gtaggtaaac caaaggattt
    35401 taaacgattt attattcaag cgacctcttg catagaacat aatgcttttt ccgaattaaa
    35461 taaaataaca tgtccaacct taattatagg aggtgctaat gataaaattg ttggaaataa
    35521 tgcttctttt catttagcag aaaaaattaa aaaaagcgaa atatttatct atgagggatt
    35581 gggacacgct acatatgaag aagcacagga ttttaatgaa agagttttag agtttttaaa
    35641 taagtaaaca cctttgttaa aaatatacat atgaagattg gaaatttaat gttaaaaata
    35701 gaaacatgaa aatatgctta actggtattt ttactattca taaccaattt ttgatacatt
    35761 atctactata aatacaaata tagcttcaat gtgattatat attgttgtat tggtaaagca
    35821 cttatacaaa cagaggaatt ttgtaaattc atattatacc cacatttgtt aacttatgaa
    35881 aatataatca aaatttttat gagcttttta tataaaaaat ataatgtttg tatacaaaaa
    35941 tattaaagac attttagtaa gttttgtata taagcaaaca tgtatttttt aatatagtta
    36001 tctaaatatt attttatata caataaaata tgactcctaa aaataaaaaa tatatcataa
    36061 atataaataa gtagatatag gttttaattt gatttataaa cctattataa aataaaattc
    36121 atgattttta taagcaataa aatttttagg aggatatatg atgaataaaa gaatgaaact
    36181 aattccgtat gaaataaatg aaaatctaag aggtgcaaaa aataaattcc catatggaat
    36241 aaaacaaatg aatgctaggg gaatgtggga tgaaggttat actggtaaaa atattgtagt
    36301 tggtataata gatacaggtt gtgatatatc tcatcctctt ttaaaaggaa aaataattgg
    36361 tggtgcaaat tttagtgatg acagtaatgg aaataaaaat atatatgagg attttaatgg
    36421 tcatggaact catgtggcgg gtattatagc tgcatctaac tataataatg aagttatggg
    36481 agtagctcca gattgtaaat tattaatagc aaaagcatta aataaagatg gtactggaac
    36541 atatcaaagt ataattaatg ctattaactt tgctgtaaat aacaaggttg atattatatc
    36601 tatgtctctt gggggaaaca aagatgataa gaagttaaaa aatgctgtca tgcaagcagt
    36661 aaaaaacaat atttctgtag tgtgtgcagc aggtaataat ggagatggtg attctagtac
    36721 aagtgagtat agttatccag ccagttatgc tgaggtaata gaagtaggtg caataaatga
    36781 aaactatttg gttgaaaagt ttagtaattc aaatactaca atagatttgg tagctccggg
    36841 aagaaatatt atatcgactt atatggataa taaacttgct attatgagtg gtaccagtat
    36901 gagtgcacca tacgtatcag gctcattagc actaattaaa gaatgggcaa gagaggagtt
    36961 tgaaagagat ttagatgaag ctgaactata tgcacaatta ataaaatgta cgagagcgct
    37021 tggaatacct agaacggaac aaggaaatgg atacttatat ttaaatcttt ataaatacaa
    37081 gaataatggc aaaagataat ttttgatttg atgataaaat agctatatta tatagagtcg
    37141 agataaataa taaaaattac ttaggtgtaa gattttacat caatgtataa aggtattaag
    37201 tgataaaatt tataaacata ttagctagtt agaattgaaa aataaatata cgatattata
    37261 gatagcacat ctggaaaagg tgtgtttttc tatgtactta tacatataaa agatttataa
    37321 gagatgcaaa agtactataa gttagaaatt tttctatgaa agattagaaa tacgatacag
    37381 tgttttgata ttataaaatg aatataaaat ataaatgata aacattatca ataagtattg
    37441 aatttcaaaa tcaactatga tattctatat ttagaaaaat aaagagattt cagataaaga
    37501 aatcttttgt tttttagatg ttagttagct ataactaact attgattaat taaaaaatac
    37561 tacaggaggt aaaaatgagt aaaatatata ttgtttattg gagtggaaca ggaaatactg
    37621 aaaaaatggc aaattttgtg gctgaaggtg tgaagttaaa aggtaagaca ccagaagttt
    37681 tagatgtgag cttactgaaa ccaagtgatt taaaagaaga agataaattt gcattaggtt
    37741 gcccatctat gggagcagag caactagaag aggggtatat ggagccattt gtttcagaat
    37801 tagaatctat ggtatcaggt aaacagattg gattatttgg ttcatatgga tggggaaatt
    37861 gtgaatggat gagagactgg gaagaacgta tgcaaaatgc tggtgctaca attattggtg
    37921 gagaaggaat tacagcaatg gaagacccaa atgaagaagc aaaagatgag tgtatagaat
    37981 taggcaaaac gttagctgaa taaatttgta tattataaaa atagtataaa tagcaactaa
    38041 tgatgatagc agtatataat aataagagag actaatatta tgatacataa gaaaatatcc
    38101 ttaatagaga tagataaaat attagtctct tttaatataa aattagattt ataatttaat
    38161 gttgtttttg aattggtaca atctcattat aaaaagataa taattgattg ataacataag
    38221 tgataaaggt agtatcttgt gcaaaacaaa gcatatttgc tccaatatta acccattctt
    38281 caatactttt cttttctatt gtaggaaaaa taataaaggg catcttatat tttttgcata
    38341 tttcagcagc atgagaaatc atatctttaa aacgccgcca ttggagacaa tgagcggcgt
    38401 tttggtgtaa tggctaagga gaggagggat aggaatgaat atccgagggt caaacagggc
    38461 aggtgtggcc atacctgcct tgcttacaga tataatcaaa gccggtaaag attgcaaatt
    38521 taccaagggt tccatctagg ggaaagtcgc attagtctaa ttaatacctg tctaaccacc
    38581 aaaccttatt gttttgccat aaacataatg ttgcttgaca gaagtaggaa tagcttatat
    38641 aataaaaacc aacagtcggt ttttaataag aaggagttat ataatgacta gaaagaacaa
    38701 tccaaagcaa gctattgaaa atatcattac catttctgca aaattgtttg ctgaaaaagg
    38761 atatgacaaa acaagtatgc aaaatattgt tgatgcttcg ggaatgtcaa agggcggaat
    38821 ttttcatcac ttcagttcaa aagaagatat ttttaatgtg gtcatggaaa ggcgctttga
    38881 acagataata gagacagtaa atcaatggct cggtgaaatg catggactta cagcaaaaga
    38941 gaagcttaga agtttagtta ggcggcattt aacggatgag gtgataaaag aatctagtaa
    39001 catgattaca agcgctatag aaagtccgca tatcatactg gcatttacac aggataattt
    39061 gaaaaaacta gcaccaatat tagcaaatgt tttacgagaa ggcatagagg atagaagcat
    39121 catcacagag ttcccagatg aatgcgcaga ggtaattttg ctgctcttta acttttggtg
    39181 tgatacagat gtatttcagg gggactttcc tacacttcgt aaacggtttc aattcttaca
    39241 gtttcttatg agacaaatag gagttgatat cctggaagat gagattatag aatcaattaa
    39301 tattttttat gaaaggaaac caatgggaca ggtagagtaa caaaactaaa atagcaacat
    39361 atttttttta atgttagagg agatatctat ggctaaaaaa attcatgaaa gaaggtactt
    39421 aaaatgatat taatcacact ttgcatacta gttgctgttt ttgttctggc gtttgccggt
    39481 ttgcgtctga tagcccccac gattatacgt acaagccata aaatagaagc tcctggaatc
    39541 gaccgcatgg aaatggtgga gatcggcggc atacagcagg cgttatatat ccggggacaa
    39601 aacgcagaca accccatcat cctttgggtt catgggggtc ctggtaattc aatgatgcca
    39661 tttttacatc tgtaccagta tgagtgggaa aatgatttta ctgtggtgaa ctgggatcag
    39721 cgaaacgtag gcaaaacata ctttgcgaac gatccggcag cagttttgca gaccatgagc
    39781 gcggagcgtg ttctgcaaga cgtccatgag gtgacagcat atttgaagca agagttcaac
    39841 aaggagaaaa ttatccttat aggtcatagc tggggaacag tgctgggaac tatggctgtg
    39901 caaacctatc cggaggatta cagcgcgtac attgggattg cgcagaccgt taatatggtg
    39961 gacaatgagc gcgtgggcta tgaaaagaca cttgaaatgg tgaaagctgc agggaagcaa
    40021 aaagatatca aggcgctgga agctattgca ccatatccgc cagcaaaata tggtccaagc
    40081 tatttggcag ctcttatgac agtaagaaca taccaaagca agtatgggct ttctataaat
    40141 atggatttgg gcaatataat cagtatactg gcaaccccgt attattcatt gagagagtta
    40201 aaaaatacgg ccattgtcaa tccaaatgcg attgacaatc aaggtgatgt attgcggttt
    40261 ttagtggaag aagctgacat aagaaattat ggagttgact atcaggtccc tgtatactac
    40321 atcatgggag aaaatgacta taatagcccc tatcttccag cgaagaaatt ttttgatgaa
    40381 atagtggcgc cagacaaaca gatttttttt ataccagatg cagaccatct gccatttctt
    40441 agcaaaaagg cagaatttga ctgcgtattg ttagaggaaa ttgctccgaa gttagcaaag
    40501 taacaactag gacagtaacg tggatatggt ggcaatttct tttactattc cagaacgctt
    40561 cagtttgttt ccagcaactg gtttcaatga ggtgcttgag atatatctat ttagagggtt
    40621 ttaagagagg actatcactt atggacattt tgtccataag tgacggggtc agcaatcgga
    40681 aagggtggtc atgctatgag tgaactgaga cctttatatc agacagttaa aaaccatgga
    40741 gtgattatga aaccataaga tgattcttgt aatgtacagg agtcatcttt tatatttatt
    40801 ttctttttta gatttaattc tctacttgat ttagatacaa gagaggcttc gccttgtttt
    40861 aagtatattt ttctacttat actattattt cttttttatt tgttttttca ctttaaataa
    40921 tacaacttta acataatttg aagctaatat cttttattga ctattgtata aagtattttt
    40981 ataatgttct tattcatata aaattttatt ccacttacta ttgaatttta ttaagaaaaa
    41041 gatttattac tttctatata atagaaaaat aagtggtatt agttatttct aggaagagaa
    41101 tatagagtat cctatattta ttacaagatt aaaaaaagca ggtttatata ttgaagatat
    41161 aagaatgctt tcatttttgt gatataagaa acaatatgtt tatgatataa gagacaatat
    41221 gatagataaa agaattcaat tatttcagca atataagcaa gatattaaaa taaaatcatg
    41281 aactagaaga gtgtatatac aaaatagctg agaagataga ctatctaagc aaaaaaggta
    41341 tgtaaaaaat aatttttcta aaagaatcca acagtttttt tatttttata agaaaaataa
    41401 tactaattgg aacaatttaa taatattctt tcttagatgt atttctatat agtattggac
    41461 aatgttatat acagttattt atatatgcaa taaaaaggaa aattatgata acatatattg
    41521 atgtaagcag taaaaatact ttcatttata gatataatta ttttgggaaa acactgattt
    41581 tacaaaataa aaaagtaatt atagaattta tcaatatatt aaaaaactga attgtagtaa
    41641 actaagtgca actaaaatta caggagtatt aaaagagtat gatgatttta tagtaatgaa
    41701 agttaatgat gatgatatta ttttaatata agaagggaag aaaaaatatt tagacaaaaa
    41761 ctacgaggtg agtttatggt ggattttatt gagtcaaata atgaagtaca aaaatttgat
    41821 tggggagagg ttatgtggat acacgaacca tcaaaaacac aattcaatag acttagtgct
    41881 ggaattgtaa gattttttcc gggaaactgc caagaaaagc attttcattt aagtgaagaa
    41941 cagcttttat atgtgattca gggagaagga atacaaataa ttgatggtaa aaaggtcaat
    42001 ataaaggaaa catctatagt ttattgccca ccatattcag aacatgaaat tataaacact
    42061 ggtaaaattg atttagtaat attaattact tatgttcctc ataaattttc gagtttgaga
    42121 caaataccta tagtattttc tgaaaacaat atacaggagt tagttaatgt aaacataatt
    42181 gaaaatcttg caaatcaaat atctaatata ttgaagctta gaatatctgt atatgactta
    42241 aagtataaag aaatatttga gactaagaaa gaaaataaat tttgcgatat ttgtaaaaat
    42301 ataaaacagt gtactaaaaa acttgttaaa agcataaata atgataactt tgaaaaagtg
    42361 taccattgtg agtatggtgt ttccagttta gagataccta tagtattaga agaaaatata
    42421 gttggatata tagaatgtgg taattttata gtatataagt ctattgatat agataaaaat
    42481 ttatctgaat tatcaagtag ttctggtatt gatataaaat acataaacaa aatttacaat
    42541 gaatttccat taaatcctaa aagtaggtta tatgtattaa aagaaaattt attaatgatg
    42601 tctgaattta ttcaggaaat agctaagagg aatttttttg aaaatcaact tagtataaaa
    42661 gatgaggaga tattgaagag tagaaaagaa aatataagac ttgaagaggc acttaaaaaa
    42721 gcaaatagta gattattaga agaagagtat attattaatc cgatagatat gttcaataat
    42781 tcttcaaaag aatatccctt tgaattagaa ctttatattg aaaaagaaat taaaaatatg
    42841 aatttagaag gtgtttataa tctaatagat acaaacaaat taagatataa tgatgttaga
    42901 gatactattc aggaaatgat atttgtattg tctagaacag tgcttagaga tttagaggat
    42961 ttaaaactta tatcttattt aagaaataaa tataataaaa aaatatcact tgtaaacagt
    43021 gatgaagatt tatggaatgt attatttgaa ttttccaaag agtgtattga taagaataga
    43081 gcattttgga gaaaagataa aggaaatcta attgaaaata taaacgaata tataaaaaaa
    43141 tattataaag aaaatataaa tttgaatagt atatcagatg ttttttttat aagtccaaat
    43201 tatttgagtt ctatttttaa tgaaagaaat aaagtttcaa taactgagta tataaatctt
    43261 cttaggatag aagaatctaa aaaatatctg ttagatagaa gcatgagtat tagtgatatt
    43321 tgtaagaaag taggttttaa taacagtagt tatttttcac aaatatttaa gaagtttaat
    43381 agtataactc caaatgaata tagaaagaat atgctggata ataagtatta aataagatta
    43441 tataatatat attgtaagaa aaattgaaag agaatgatgg aggaatttta tgttttcagt
    43501 tattttttta tgtatagggg ggtttttagc tgcttttgta gattctatag caggaggagg
    43561 aggacttata agcatgcctg ttcttatggc aattggagtg ccagtacatc ttgccattgg
    43621 tacaaataaa tttgcagcat cagcaggatg tataagtagt gcctatagat atgcaaagtc
    43681 tggaaaaatt aataacgacc ttttaaaaaa attagtacca tttactatta ttggtagtgt
    43741 tctaggtgtg agatgtgtat tatcaataag tgaagagata ttaaatgttt tggttgtggt
    43801 tatgatttta atagtggcta tttacacctt tatttctaaa aatttaggtc aagaagataa
    43861 ttttgaagct gttaataaga aaaatttaag actagggatg cttatggctc ttataatggg
    43921 tttttatgat ggtttttttg gtccaggtac aggaactttt ttgacctttg gatttataaa
    43981 aatatatgga tatgattttt tacatgcttc tgcaaataca aaaatattaa acttaacaag
    44041 taatataact tcattgttat tattcatgat aaatggtcaa gtagattata aaattgctat
    44101 agtgtttgca ttagtgatga taatgggagc ttatgtaggt gctaaagttg ctataaagaa
    44161 aggttcaaag atgataaaac caatattttt agtaatggca ttatttatgg tcgtaaaatt
    44221 ggtatatcaa acattagttt agcttataga ctttttaaat ttataagtaa ttgtaaagct
    44281 tttatattta atctaatcat atagctttat aaaaattcta attatcttct aatatagttc
    44341 atatataata cacatataaa ctgtaatctt acaatagaag gattatatat cataaaaata
    44401 taaccttgat ttatatatat gaaatatatg gtaatttgta ggaggaatgt ttatgaacat
    44461 atcaagaaga gctatgaaga taattgaact ggcacaaaaa attgctaata aaagaggtgt
    44521 aacagtacaa gacgcttgga atgatgcgat gaaagaatat aaagaaaaat atgaatatgt
    44581 tgcataagat atgcgttata ttttaaatat aagaaaatat aaaacaaaaa agattgtctc
    44641 aaaataagat tgtactgaga ctcaaaagtt agattttata caggaatgga attttcattc
    44701 ctgtattttt aattttacat aactttaaat tcatattcaa atctatattt aacaaggtta
    44761 tgctaaatta attttttttt attcttttgt tattataata ataaatatat tctgttatag
    44821 ttgtatctaa ttagtagatg tttttatgta cttttataca gtatatttct cgtttcattc
    44881 ttttctattt aaataggact taactacttt ttaaattggg tttagctact tttaatttaa
    44941 aattaaaagt attgttatat atataagtac ctcagtcatt aggtttttgc tttaacaatt
    45001 atggtgcaat acacttttgt taagttaaaa aaattagata aagtaagatt aaataaaagc
    45061 gacttaagta aattgagaat cttaatatga aaattttcaa taaatattta gaaataacta
    45121 tttagaaaaa tttctaaata gctattgaaa taaaatggat gttatgttat attctattta
    45181 gatgaaattc taaatagcga ggtgatggtg ttggggtttc cagaaacatt caaagctctt
    45241 tcagacccta taagaagaga aatattggtt atgttgaggg agaataaaat gtcagcagga
    45301 gaaattagtg aaaaatttaa tatgacgaat gctacaattt cttatcatct atctcaacta
    45361 aaaaaggcag gactcatatt tgaaacaaag tataagaact ttattttcta cgaaataaat
    45421 atttcagttt tcgaagaggt tatgctttgg ttttcacaat ttatggagaa gggagaaaaa
    45481 gataatgaaa aaagcgataa ataaacaatt tattttatct actttaatat gttttatacc
    45541 atttattgta tcaatatatt tttataatag attaccaaat gaagttgcaa ttcattttga
    45601 taattatgga aatccagata attatgctcc aaaggttata gcagcttttg gtgtaccatt
    45661 gttaatgcta tgtatccatt tgtatacatg gtttagactt gagaatgagc ctaagaaagc
    45721 taatttttca aatgttatac aaaatttatc aaaatgggga gttgctatac tttcagtaat
    45781 tatacaaata atgatggttt tatattcaac aggagttagt ttggagtcta atttttatac
    45841 aggattaatt ttaggaataa tagttatttt atttggaaac tatcttccta aatgtaaacg
    45901 aaattactca gtaggaataa ttttgccatg gactctgaat gatgaagata attggaataa
    45961 gacacaccat ttagctggat ggatttggct tattggtgga atattattaa ttattaatgc
    46021 atttattaat attccttttt ataatatctt tgtaatcttt gtaattgtaa tactaccatt
    46081 tatatattct tatttgatgt ataaaatttc aggtaaaaat aactaatata attaatcaat
    46141 ataataatgt ttggataaga ataatatatt tcagaactga gataggtaat aaagaaatta
    46201 ctaagatttc tattttagtt atgaaaaaat cttacttata tgataactta ttgagatttc
    46261 aaaaaataat ataaattagg ctaatgaaca taaaatgaaa atttgtattt aatattgaaa
    46321 atataagtac agtgtgatat tcttataaga aaaacatagg aggtagaaga tgaatactag
    46381 agaaatgaaa gaatataggg tattttacaa taaaaaatta agcgaaacag atgagttttt
    46441 tagagtattt ggaagtcttg atgataagac ttattcagaa ggggctataa gtaaaaaaaa
    46501 taaggaatta atgggactag ctatttcaat tttaagccga tgtgatgagt gtatttgtta
    46561 tcatattgag ggttgtatta attctggagc aagtaaagat gaaattatag aagctataaa
    46621 aataggtgta attggtggcg ggtctattac atatccaaac gcaagatttg caataaaaat
    46681 tttagaagaa tttaatatat aattttgata gacgtagttt atttagacta ataataatag
    46741 tctatttaag
//
LOCUS       DAEOTL010000025        45490 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEOTL010000025 DAEOTL010000000
VERSION     DAEOTL010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.025"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..329
                     /locus_tag="KRH82_001687"
     CDS             <1..329
                     /locus_tag="KRH82_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBG8654968.1"
                     /translation="VAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTLFL
                     SKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSAGV
                     DQVITL"
     gene            491..676
                     /locus_tag="KRH82_001688"
     CDS             491..676
                     /locus_tag="KRH82_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654969.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            703..1788
                     /locus_tag="KRH82_001689"
     CDS             703..1788
                     /locus_tag="KRH82_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBG8654970.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            1781..2239
                     /locus_tag="KRH82_001690"
     CDS             1781..2239
                     /locus_tag="KRH82_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654971.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            2268..3359
                     /locus_tag="KRH82_001691"
     CDS             2268..3359
                     /locus_tag="KRH82_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8654972.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            3364..3588
                     /locus_tag="KRH82_001692"
     CDS             3364..3588
                     /locus_tag="KRH82_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654973.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            3598..4161
                     /locus_tag="KRH82_001693"
     CDS             3598..4161
                     /locus_tag="KRH82_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654974.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            4122..4751
                     /locus_tag="KRH82_001694"
     CDS             4122..4751
                     /locus_tag="KRH82_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8654975.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            4791..4928
                     /locus_tag="KRH82_001695"
     CDS             4791..4928
                     /locus_tag="KRH82_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8654976.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            4928..5680
                     /locus_tag="KRH82_001696"
     CDS             4928..5680
                     /locus_tag="KRH82_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8654977.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            5693..6178
                     /locus_tag="KRH82_001697"
     CDS             5693..6178
                     /locus_tag="KRH82_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654978.1"
                     /translation="MSQIEKYNSLNNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            6185..6334
                     /locus_tag="KRH82_001698"
     CDS             6185..6334
                     /locus_tag="KRH82_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654979.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(6471..7292)
                     /gene="yidA"
                     /locus_tag="KRH82_001699"
     CDS             complement(6471..7292)
                     /gene="yidA"
                     /locus_tag="KRH82_001699"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBG8654980.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCMNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            7785..9479
                     /locus_tag="KRH82_001700"
     CDS             7785..9479
                     /locus_tag="KRH82_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBG8654981.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKIYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      9811..9921
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            10025..10396
                     /locus_tag="KRH82_001701"
     CDS             10025..10396
                     /locus_tag="KRH82_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBG8654982.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            10491..11438
                     /gene="trxB"
                     /locus_tag="KRH82_001702"
     CDS             10491..11438
                     /gene="trxB"
                     /locus_tag="KRH82_001702"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBG8654983.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            11523..11840
                     /locus_tag="KRH82_001703"
     CDS             11523..11840
                     /locus_tag="KRH82_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBG8654984.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            12109..13395
                     /locus_tag="KRH82_001704"
     CDS             12109..13395
                     /locus_tag="KRH82_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBG8654985.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            13507..13980
                     /locus_tag="KRH82_001705"
     CDS             13507..13980
                     /locus_tag="KRH82_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:13639..13641,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBG8654986.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            14012..15322
                     /gene="grdB"
                     /locus_tag="KRH82_001706"
     CDS             14012..15322
                     /gene="grdB"
                     /locus_tag="KRH82_001706"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:15059..15061,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBG8654987.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            15579..17111
                     /locus_tag="KRH82_001707"
     CDS             15579..17111
                     /locus_tag="KRH82_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBG8654988.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            17122..18267
                     /locus_tag="KRH82_001708"
     CDS             17122..18267
                     /locus_tag="KRH82_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBG8654989.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            18577..19656
                     /locus_tag="KRH82_001709"
     CDS             18577..19656
                     /locus_tag="KRH82_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8654990.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHAAIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            19769..20368
                     /locus_tag="KRH82_001710"
     CDS             19769..20368
                     /locus_tag="KRH82_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654991.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(20555..21427)
                     /locus_tag="KRH82_001711"
     CDS             complement(20555..21427)
                     /locus_tag="KRH82_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8654992.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            21843..23246
                     /locus_tag="KRH82_001712"
     CDS             21843..23246
                     /locus_tag="KRH82_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654993.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            23273..24817
                     /locus_tag="KRH82_001713"
     CDS             23273..24817
                     /locus_tag="KRH82_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBG8654994.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            24848..26239
                     /locus_tag="KRH82_001714"
     CDS             24848..26239
                     /locus_tag="KRH82_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBG8654995.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            26432..27928
                     /gene="abfD"
                     /locus_tag="KRH82_001715"
     CDS             26432..27928
                     /gene="abfD"
                     /locus_tag="KRH82_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBG8654996.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            28063..28338
                     /locus_tag="KRH82_001716"
     CDS             28063..28338
                     /locus_tag="KRH82_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8654997.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENVEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            28362..29669
                     /locus_tag="KRH82_001717"
     CDS             28362..29669
                     /locus_tag="KRH82_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBG8654998.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            29689..30807
                     /locus_tag="KRH82_001718"
     CDS             29689..30807
                     /locus_tag="KRH82_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBG8654999.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            31094..32014
                     /locus_tag="KRH82_001719"
     CDS             31094..32014
                     /locus_tag="KRH82_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBG8655000.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFIPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGNKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            32129..33286
                     /locus_tag="KRH82_001720"
     CDS             32129..33286
                     /locus_tag="KRH82_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBG8655001.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(33371..34870)
                     /locus_tag="KRH82_001721"
     CDS             complement(33371..34870)
                     /locus_tag="KRH82_001721"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBG8655002.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            35466..36890
                     /locus_tag="KRH82_001722"
     CDS             35466..36890
                     /locus_tag="KRH82_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBG8655003.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIDEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            36925..39054
                     /locus_tag="KRH82_001723"
     CDS             36925..39054
                     /locus_tag="KRH82_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBG8655004.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSRIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            39084..39506
                     /locus_tag="KRH82_001724"
     CDS             39084..39506
                     /locus_tag="KRH82_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655005.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            39525..40676
                     /locus_tag="KRH82_001725"
     CDS             39525..40676
                     /locus_tag="KRH82_001725"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBG8655006.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      40782..40883
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            41066..41638
                     /locus_tag="KRH82_001726"
     CDS             41066..41638
                     /locus_tag="KRH82_001726"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBG8655007.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            41702..42352
                     /gene="fsa"
                     /locus_tag="KRH82_001727"
     CDS             41702..42352
                     /gene="fsa"
                     /locus_tag="KRH82_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBG8655008.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            42504..45428
                     /locus_tag="KRH82_001728"
     CDS             42504..45428
                     /locus_tag="KRH82_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655009.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        17905 a         4990 c         8457 g        14138 t
ORIGIN      
        1 aagtagctta tatttttagt agtactaata cacataaaat tctagacaaa atgataatac
       61 cacaacttga acaaggaact catggagtag acgttctagg gatgtttttc tttatggata
      121 ataccttatt tttatctaaa ggtaatcctg taggcgagag actaagtaaa ttacatgaaa
      181 aaactgatat gataataatg gcttgtgacc aatgtgctat agaaagaggt atagagaata
      241 atttggttga tggagctaca attggatgtt tcccaaacct atatgcttgt ttaggcagtg
      301 caggtgtgga ccaagttata acgttataaa ttagtatagg atacaatcca tagaaaaatt
      361 tattttctgt ggattatttt aagtaaaaga taaattgttt aaagtagggg attaacaaat
      421 gtctaaaatt ttagttgaat ttataaacac ttgaccatct tgtgatgaac atggagtgtt
      481 tataaaaaaa atgtcagaaa aatatgctga taaattggaa ataaaattat atcaagcagg
      541 gaaagatttt tcgtatataa aaaaatatgg gattataaca aaaggaactt taataataaa
      601 tcagaaaaag aaatatgata gattaaataa agatacaatt gaaagggcaa tagtagaagc
      661 tataaacaat aattaaaagt ttaaaaatta ggagtatcaa aaatgaatat attagaaatt
      721 gttttaaatg gagttaaaga tactatagta gcttctatag ttacactgaa tggagcatca
      781 ggatggctta tgataagttt tatattggca ggtgtacttc acaatgtttt aactccaaga
      841 aggtttcaaa aacaacttgg aaataagaaa ttttcttctt taattaaaag tactatctca
      901 ggaatgtttt taccaatatg tagttgtgga gtaataccac ttggaataag tatgtattat
      961 tcaggagcat atttaggacc agtacttgct tttatgacat caactccaat aataaatcca
     1021 atagctgtag ttctttgtct aggtctttta ggtcctaaag ttacaatcat ttatctaata
     1081 gctggttttt tagtaccatt tttagtagga tttttaggaa attgttttgg aaaagaagaa
     1141 ttatcacttc ataatgattc agaggaagaa gtaatagaat tagaagaaga aaaaagaagt
     1201 tttatgggaa atatgattga tggtcttaaa tggtcttttg gtgaattagc ccttactatt
     1261 agtaaatatg tagtaatggg tatggttttt gcaggattta taacaactat ttttccaaat
     1321 agtataattc aaaaatattt aggaaatcca ggtttgctat ctcttggaag tatagcaata
     1381 cttgcatgtg ttatgtatgt atgtgctgta ggacatatac cgtttatagc agcccttgtt
     1441 gcaagtggag catctcctgg tatagcgata acatttctaa tagctggagc agctacaaat
     1501 ctaccagaac ttataagtat gtttaaactt attggaaaaa gaactgttat tatatattct
     1561 gtaactttga cactgtcttc aataataatt ggatatataa caaatttact tttagtgaat
     1621 aataactcag taaatttaga tgcaacaaat tcttcaatac agttggcaaa taaactaatg
     1681 ttaaatatac ctgatagttt tgagtatgta tgtactattt taattatttt atttgcattt
     1741 aaatcaataa taccaaagat gaaagaggtc ataggaaatc atgcttaaaa agatagttat
     1801 aatatcctgt atagtagttg tgttaatcat tttatcaaaa atagttgatg ataacatcaa
     1861 agaagatgct tctattccaa atgtgaataa agaaacatta gaatatttta gaaaaaatta
     1921 taaagaagac ataataactt gtgctgaaga agacttaaat aatgatggaa aaaaagattt
     1981 agtagttata tataaaaaaa gcaataattc aaatgaaatg gtagtcgtag tttctgataa
     2041 aaatagccac tatataacaa agccaatacc agcacctata gagaatcaaa cgataacctt
     2101 taaaaatatt gatgataaag caccaataga agtaattgta tcagggtcta aaaatggtaa
     2161 tgtaggatat gctatttaca gagtagaggg taaaaaattt gttgatttat ttggcgaaga
     2221 tatggacaaa tgttgctaaa aataatacat aaaggtggga aatttatatg aaattatcta
     2281 agaagattca agcattaatc ttatttggtg taatgggtac atctatatta acaggatgta
     2341 gtagtaaacc aaaagaaaaa gaagaagcaa aaactggaaa agatgattat acaataacag
     2401 taggttatta taattgtgac catatgactg cgggaccagt agcagaatcg gcaggaatat
     2461 ataaagattt aggtcttaat gtaaaaactg ttggaaatgg taaagttcct gaagctatgg
     2521 cagcaggaaa aatggatgca ggttacatag gaactaaggg gttagttgga gcaataccta
     2581 agggttcgcc aataacaata gcagctaaca accatactgg tggttctgaa tatttaatag
     2641 tttcaaaaga tataaaagaa cctaaagatt taataggtaa aaaaattgca acagatatga
     2701 gtgatttctt atggacaagt gattatggtc cagaaacagg tctaccaact gacccatcaa
     2761 aatatgaagt tgtaaatatg gattcagaca aagataaata tttagctctt aaaactggga
     2821 aaattcaagc ttttacatct tgtgaccctt ggggttctgt agctgaaaat gacggtgcag
     2881 gaaaaataat agcatctact caatataaag aaaaagctaa tggcaaagaa tataactgtt
     2941 gttcattctc attaaacaaa aactttataa aagaacatcc agatttagca aaaaaattgg
     3001 ttctagcaca tacaaaagca atagaatata tatatacaaa tccagctgaa gcagctaaaa
     3061 tatttgcaaa atattataat gtagaagaag aagttgcact tagaactatc tataagaaga
     3121 ctgttggaga aggtagaact cttacttgga aagttacagg tgaagaatat aaaaataatt
     3181 tacaaatgta taaagattta aaggctttag atgatatacc taaatatgaa gatacgattg
     3241 atacaagctt attggactct tgtggagctg atgattttga caaatttata aaagaaaaag
     3301 ttaacccaga gtttcctgaa ggtatgagtt atgaagactg gaaagcaaag gtattataaa
     3361 taaatggaga atatgaaaaa tataataata ctttttatca ttattttggg aagtatattt
     3421 ataatatttt ttaattttga agataaagaa gaaataaaag gaaaattaag aataggggta
     3481 tctgatgata cctctggttt tgtaataaat tatatggtaa atagagacta ctttgaaaat
     3541 ataaaagtaa gtgatataat ggatattttt acaattaatg attgctgagc aagtacaatg
     3601 cagtgggctc tgagttcaga ggaaatagat atagcaatca tatgtaaaga tgctgcaaaa
     3661 caatatgtaa atgtaaatag tggatttgaa attgttggta ctgtagttca aaattctgat
     3721 atatttctat taagtgataa taatcctgaa aagataggag tcattcaaaa tagagattac
     3781 cagtcagaat tggttaaaaa atactacaag aatgtggaag tagctccctt attagggact
     3841 gcactagcat atggattaga aagtaattta gtagatggtg ttgtaataga ttgcataaag
     3901 tcaattgggt tagagggtaa aagaaaatct acaactaaat taggagatta tgatacctat
     3961 gtattagttg taaataaaga gtttaaaaaa agtaaagcat atagtgattt tataacactt
     4021 tacaataaaa gcgttgatgc tttaaagaat aaagctacat ttaagaaagt attaaaagag
     4081 tacaggaata taagaaatat agatatggag gaaataagca attggaaatt aaaatttcta
     4141 aagataaaag cgatagatta actaagaaaa aaactgatgg tagtatggat attttatata
     4201 aaataatact attagttatt atatttttag tctggcattt tgcagcaaaa gatataggga
     4261 gttctttgtt acttccaatg ccagtagatg taataaaagg tttctttttc tgtgtgacag
     4321 atgcagagac agtcactaat ctttttataa cattgcagag agtacttaaa ggttttatgt
     4381 atgcattatt gtttgggctt ccaataggat ttattatggg attttctaaa acttttgaaa
     4441 gggttttatc tccagtagta gattctgtaa ggcaagttcc aataatggca tgggttcctc
     4501 ttactatagt atggtttggt ataggagatg gtccaacaat atttttaata gctttttcag
     4561 gggttttccc tataatttta aatactattc aaggagtaag agcaatatca aaggattatt
     4621 ataatgcagc tagaagtatg ggagcatcgc caattgtgat atttacaaat gtaattgttc
     4681 ccgcatctct tccagatata ctaactggtt caaggattgc tataagtaca ggatggatgt
     4741 ctgttatctg agccgagttt atagctacga gtgccggtct cggttactca atggtacaag
     4801 ctcaaacatt aatgcataca gatgtattaa ttgggcttat gatatttgca gctttaatag
     4861 gatttataat agatagggta ttaaagttta taaataaaat cctttgtaga tggaggtttg
     4921 cagattaatg aagttaagtg taagggatat aaataagaca tttgtaaata atagagtaca
     4981 tacaaaggtt ttagaagata taagtatgga tatagatgat ggacaatttg tctgtctttt
     5041 aggaccatca ggttgtggaa aaacaacttt acttactata ataggtgggt ttcaaaaatc
     5101 agaacgtgga gatgttttta taaatgataa aagagttaaa aaaccgggca tagatagagc
     5161 ttttatattt caaaattatg ctttatttcc ttggaaaact ataagaggta atgttctatt
     5221 tcctatgaaa cagcagaaaa taccaaaaga aaaaagagaa gaaatgctag aagaactttt
     5281 ggttatgtca gacttgaaag gaaaagaaaa actgtttccg catcaattat ctggaggaat
     5341 gaaacaaaga gtggccatga taagagcttt agcatgtaat ccagaggtat tactaatgga
     5401 tgaaccatta ggagctgtag attttcaaat gagacaaaat ttacaggaag agctagaacg
     5461 aatatggata aagaagaaaa taactgcatt aatggtaact catgatgttg atgaagctgt
     5521 atatatgagt gatagagtta tagtaatgtc gagagataaa ggaagaatta ttgatgatat
     5581 aaatatagat attccaagac ctagaattag aggaagccaa aaatatgaag agtacaaaaa
     5641 caaattaact gatactttat caaagtgtta tgaagtttaa agaggagtag acatgagtca
     5701 aatagaaaaa tacaatagtt tgaataatac acaacagaaa ataagaatct ctattatgga
     5761 tatgataata gataaaggtt ctagtgttac acttcaagaa gtgactgaat atgtaagtaa
     5821 aaagttgaat atagaaaaag aatatataga aaggacacta caatatttta tttataaaaa
     5881 tataatggtt gttgatggga atagtataaa ttttatatat cctgtatcag cattgccaac
     5941 aaatcataaa gtaactttga gagataatag aagtttcagt gcaatgtgtg ctatagatgc
     6001 tataggaacc tcttgcacat tcaaccaaga tataaaaata aactctattt gtagtgctac
     6061 aggtaaggaa atagaagtaa ttataaaaaa tgaaaagatt gagtatgtga ataatccaaa
     6121 cttaagagtg cttcatataa atcttgataa gcatctaaat tgggctgcta gttgctgaaa
     6181 tataatgaat ttcttctgga cgaagagtga ttttgatgct tggacaaacg aagcgggatt
     6241 atctgatgat gaagatatat attgtttaga tattaatgag gcaatagtag aatcatataa
     6301 aatatttaaa ctcaaacaaa aggtactatc atagatatac atatatgaaa aactaaaaat
     6361 gacctttaga taaaaatgat aggtaatatc catactatat aaattagtat agagtaggga
     6421 tgtgaaaagt atttaaatct aaaggtatat ttttagtttt ttttagatga ttagatagcc
     6481 ttattaagta tatatttatt tataaccttt gcaactccat tttcattatt agtatcagta
     6541 acataatctg caatttcctt tatactatta cgtgcattcc ccatagccac accaagacct
     6601 gcatacttta tcatatgttg gtcattttct tcatcgccaa cagcaatagc attttctata
     6661 ggtatattta gattcataca taatgtttta agagcagttc ctttattagt agttttacct
     6721 aaaaattcta gataaaaagg agcagacctt actatagtat atttattgaa taaattttta
     6781 ggtagttgct gtatgatttc ttccaatctt tctggttcat caactatcat aattttacag
     6841 attttaatag attcatcaat tttatctttt tgtatatatt tgacttctat attatttaat
     6901 ttcgcttcat gaagtgtata tttgccaggc gtttcatttg gtgtaattaa atttgtcatt
     6961 gtatttatgt gtattttagt cttatatttt ttacaaacgt tattatatat aaaatcaaaa
     7021 tcatctaaac tcatttctac atcatgtatg attttctcac ttttaacttc ttgaataatt
     7081 gctccattaa agcatataac ataatcacct tcatctgtta aatttagttg atttagaagt
     7141 tcttttacac caggaagagg tctgcctgtt gttataacta cttttgcccc agcccttttt
     7201 gcctcctgaa tggactcaaa gacttcagga gtaatccttt tttgtgtatt taatattgtt
     7261 ccatcaatgt ctagtgcgat taatttgtac atatcaacct ccaataaatt atatactcaa
     7321 atttcctgtg aaaacgttga cacagctagt gttgaacaaa gtttcagtgg gaaatatggt
     7381 ttgttttgta tactattata tcaagagata agtaatttat aaagtttaat aatattaatt
     7441 ttttgataaa aatattactt atgtgagatg agaatgtaaa aactttgtaa tcaataattc
     7501 caaaattctt aattacaaat aatggtatcg tttgcattgt taatataaat aaatgtatat
     7561 tatatagtta gaagtttgaa taaatagact gatggtaatt tgttatatta gttagttttg
     7621 tgttataaaa tattgtaatt ccattaatca tatgttatta ttcaacatga ttataatata
     7681 aagaatattt gatatatata ataatttata aaagagtatt acatagtaca tgtaaatcta
     7741 tatttataaa tacaataaag taaagttgta aaggagtgct ttaaatgaag ttttcagagt
     7801 ttaagtatga aagacccaat tataatagta tgaaaaaaga gtttttgagt tgtgtagaag
     7861 atataaataa ttctcgtaat tataaagagc aacaaaaaaa tatacataag attaatttat
     7921 taagaaataa aatagaaacg ttgtcaaata tagcttcgat aagatatagt acagacacat
     7981 ttaataaatt ctacaaagaa gaaaaaaatt attgggatga atatatgcct ttgtatgaag
     8041 aattaaattc atatttttat aatgccattg taaattcaaa atttaaatat gatttgataa
     8101 aagagtttgg agagcaattt ttcacaatag tagagtattc tttaaaaagt ttttccaaag
     8161 aaataataag tgaattgcag gaagaaaata aattgtgttc agagtatact agacttttag
     8221 cttcagctga gataatgttt gatgggaaaa taagaaattt atctggtatg gggaaattca
     8281 tgtattctaa gaatagaaaa acaagagaat tagcaaacaa agcatattat aatttctttg
     8341 aagaaaatga aactaaattt gatgacatat ttgataaatt ggttaaactt agagataaga
     8401 tgtctaaaaa attaggtttt gaagattttg tagagcttgg gtatgttaga atgatgagaa
     8461 gtgactacag agaatatatg ataaaaaatg ttagaaaaca agtactaaaa tatgttgttc
     8521 caatggcaaa tgagctttat gaaaaacaag ctaaaagaat tggtctagaa tatttaagtt
     8581 acatagatga aggcgtggaa tttttaacag gaaatgcaag tttaaaggga gattcaagat
     8641 acataattca aaatggtaaa aggatgtatt ctgaactgtc aaaagaaaca aatgaatttt
     8701 ttgattttat gttagaaaat gaacttatgg atttagaaac gaagaaagga aaaggagctg
     8761 gagggtattg tacttatata ccagattata aatcaccatt cattttttct aattttaatc
     8821 aaactgctga tgatatagat gtgttaacac atgaggcagg acatgcattt cagttgtata
     8881 tgtctagatg gattgatatg ccagaaatta attttccaac gcttgatagt tgtgaaatcc
     8941 attcaatgag tatggaattt ataacatggc cgtggatgga tttatttttt aaagaagata
     9001 cagataagta caaattcact cacttatcat cttcaattaa atttatacct tatggagtaa
     9061 ttgttgatga atttcaacac tatatttaca aaaatcctaa tgtagataag tcaaaacgaa
     9121 aagaaatctg gagattttta gagaaaatat acttacctca tagaaaatat ggtgataatt
     9181 cttttttaga gagaggttgt tggtggttta aacaaggaca tatatttaaa aatccgtttt
     9241 attatataga ttatgtatta gctcaaattt gtgcgttaca attttggaaa aaaatgattc
     9301 aagatagaga tgcaggatgg aaagattata taaatatctg taaagttgga ggaacaaaat
     9361 catttttaga tattgtgagt atgggaaatt tgtattctcc atttgatgat ggctgtattg
     9421 agtctattat aggtgatgtt aaatcttggt ttgatgaaat aaatgacagc aaattataaa
     9481 aaattatgag aattttattg tataaaagtg aaaaattaaa aaatatataa aaagtgatta
     9541 tttgttgtga aaatagtctt gtttttaact aaattgataa aataaactaa aaaagatttg
     9601 tacttaaaaa aaaaagaaaa tacaagaaat atgcaatatc aacatttgga aaaaaaagta
     9661 aaaatgtata caaaatacat ataaaaaaac tattgcaaat tttatagaat gtttatatac
     9721 ttaagtcaac agagatagaa aaaagctatt tatagaaaac aaaggataaa ttgcttaatt
     9781 ttaaattttc tgaaaaaaat aataatccgg atgaagagta tgggagactg ctttataaaa
     9841 agcgaccgaa gggacaagtt taatcttact tacccaaaag attagatgaa attctcaggt
     9901 aaaggtgact gtacttggac ggggctctga aaatgatttt aacagggaag acaaattggg
     9961 agatttgttt ttcctgtttt ttatttatca agtaataaat aaaagtttga aagagagtaa
    10021 aaaaatgata ataattacga ataatccaaa agtaaaagaa gaagttcaag gcagagaagt
    10081 tttgtttaaa gacacaactt atattggaat cttagaagca agtagagatt tgatacatga
    10141 aggttatgaa cttttatctc atccactcta tgggagtgta aagccaaatg aaacacctta
    10201 caggactgtt atactaaaga aaggaaatcg tttggatata aactctttaa ccttaattga
    10261 agaagcaatc atcactgcaa gtaaatttca gaataataaa aagactccaa aatggacaga
    10321 aagtgttcaa gatgatttta gagtaattga ttatgatata ttttataata caatacaaag
    10381 aatgcagtat gaataaaaaa attgttaaaa agttattaaa acagcctaaa tattaaatct
    10441 aatttaatat taaataaaat gagaaattta attggggagg ataagtcaaa atggaaaatg
    10501 tgtatgactt agtaataatt ggttcaggac cagcagggct tgcagcaggt ctttatggag
    10561 caagagcaaa gttaaaaact ctaatcctag aaaaagacaa gactggtgga caaattgtaa
    10621 taacacatga aattgcaaat tatccagggt cagttccaaa tgcaacagga ccaagtttaa
    10681 tagctagaat ggttgaacag tgtaaagagt ttggagcaga aatgctaaga gacaacattg
    10741 ttgatactga gctagatgga gatataaaag ttttaaaagg ggaaaaggca gaatatagag
    10801 caaaagcagt aataatagga acaggagcaa caccaagaaa gattggttgt cctggagaaa
    10861 aagaacttac tggtaaaggg gtttcatatt gtgcaacttg tgatgcagat ttctttgaag
    10921 attttgaagt atttgttgta ggtggaggag acagtgcatt agaagaagca atgtatttaa
    10981 ctaaatttgc tagaaaagta acaattgtac atagaagaca aggatttaga tgtgctaaga
    11041 gtgttgaaga aaaagcaaaa gctaatccaa agatagagtt tttattagat acagtaattg
    11101 aagaaatcaa aggtgatgga atattagaat cagttgtatt taaaaataaa gttactggag
    11161 aaactcatga atactttgca gatgaagaag atggaacaat gggagtattt gtgttcgttg
    11221 gattagatgc tcaaactgat ttattcaaag gtaaagttga tatggatgaa aaaggttaca
    11281 taataactga tgaagatatg agaactaaca taccaggcgt atttgcagca ggagattgta
    11341 gatctaagac tctaagacag gttgtaactg caactaatga tggagcaatt gcatctatag
    11401 tagctgagaa atacattgat gaaaaatttg ggaactagaa tctgtaaatt aagaaatagt
    11461 gtctgtaaat ttaatgaata atatttaaaa ttaaaataaa aatttcaagg gggaataaga
    11521 aaatgttaga tttagataag gctacatttg aagaagaagt tttaaatgca gaaggttttg
    11581 tatttgttga tttttggagt gaaggttgtg agccttgtaa agctttaatg ccagatgttc
    11641 ataaattagc tgagacttat ggggataaaa taaaattctg taagatggat acaacaaaag
    11701 ctagaagatt agctataaaa caaaaagtat taggtcttcc aactatggct atatacaaag
    11761 atggagaaaa agtagacgaa gttactaagg atgatgctac agttcctaat atagaaaaca
    11821 tgattaaaaa atatctttaa tatgttgata aattattaac attaaaagaa aaaatctatt
    11881 tttatctgaa gataagaaga aaaaggtttt tatgtccaac tttgttaaaa aaataatttt
    11941 aaataaaata atttttttac aataaatatt ttttagtaat aaaataaaga tttaaggcat
    12001 aaaaacacaa taatatatct ttaaaaaaat aagataaatt gtaaaatgat ataattttga
    12061 gaaaaactca aatgcatata cacaaattaa ataacaggag gtgcaagtat gcgtcttgaa
    12121 ttagggaaaa tctttataaa agatattcaa tttggtgatg taacagaagt aaaagatgga
    12181 gtattattca tcaataagca agagatgcta caagaaattg gtggagatga gcatattaaa
    12241 tctatagata tagaattagc tcgtccaggt gaaagcgtaa gaataacacc tgtaaaagat
    12301 gttattgagc caagagtaaa agttgaaggt aatgggggaa tcttccctgg tatcatgtct
    12361 aaagttgaca ctgtaggaga aggaaaaact catgctttaa aaggtgtagc tgttgtaact
    12421 actggaaaaa tagtaggttt ccaagaaggt ataatagaca tgactggaga aggagctaag
    12481 tacactccat tttctaaatt aaataatgta gtagtaatag ctgaacctat tgatggttta
    12541 aaacaatacg ctcatgaaaa agctgttaga atgataggat tcaaagcagc aatgtactta
    12601 ggagaagtag caagaaatct tactccagat gaagtttcag tatatgaaac taaacctctt
    12661 cttgaatcaa taaaagaata tccagagctt ccaaaagtag gatatgttta catgcttcag
    12721 actcaaggtt tattacatga tacttatgta tatggagtag atgcaaaaca aatagtacca
    12781 actttattat atccaacaga attaatggac ggagcaattg taagtggtaa ctgtgtttct
    12841 gcatgtgaca aaaacccaag ttatgttcat ataaacaatg gggttgttga agacttatat
    12901 gcaagacatg gtaaagatat aaactttgta ggtgtaatta taactaatga aaatgtttat
    12961 ctagcagata aagaaagatc ttcaaactgg acttctaaat tatgtaaata tttaggatta
    13021 gatgcagtta tagtttcaca agaaggtttt ggaaatcctg atactgacct tataatgaac
    13081 tgtaagaaga tagaaatgca aggtgttaaa acagttatag ttacagatga atatgctgga
    13141 cgtgatggag gttctcaatc acttgcagat gcagatgtaa gagctgatgc tgttgtaaca
    13201 ggtggaaatg ccaaccaagt tgtagttctt cctaagttag ataaagttat tggacattta
    13261 gaagtagtag atgtaatagc tggtggttct gatggaagtt taagagctga tggaactatt
    13321 gaagttgaaa tccaagctat aacaggtgca actaatgaaa caggatttgg tcatttaact
    13381 gctaaaggat attaagaagt attttattaa acgattgagt aatgttaata aaacatatta
    13441 tagataatta taataagtgt tatagatata taaaaatata ttagaaatat aataaggagg
    13501 attattatga gtttacttag taataaaaag gttcttataa taggtgaccg tgatggtata
    13561 ccaggacctg cgatagaaga atgtgtaaaa acagtagaag gagcagaggt tgttttctca
    13621 tctacagaat gctttgtctg aacagctgct ggggctatgg acttagaaaa tcaaaacaga
    13681 gttaaagatg ctgctgataa attcggagct gaaaatgttg tgattttact aggtgctgct
    13741 gaagccgaag ctgcaggtct tgcagccgaa acagtaactg ctggagatcc aactttcgct
    13801 ggaccacttg ctggagttgc cttaggatta agtgtttacc acgttgttga ggaaccaata
    13861 aaatcattat ttgatgaaag tgtatatgag gaccaaataa gtatgatgga aatggtttta
    13921 gaagttgaag aaatagaaga agaaatgtct ggtataagag aagaattttg taaattttaa
    13981 tgcctaaaag caaaaggggt gaaactaaga gatgggaaaa ctaaaagcag tacattatat
    14041 taatcagttc tttgctggta taggtggaga agaaaaagct gatactaagc cacatgtggc
    14101 agaaacttta cctccaataa gtttacaact tgataaatta ttaggtgaag atattgaaat
    14161 agttggaaca gtagtttgtg gagatagcta tttcaatgaa aatatagata gtgcaagtga
    14221 agaagtttta tcaatggtaa aaggttttga accacaactt ttcatagctg gtcctgcatt
    14281 taatgctggt agatatgggg ttgctgctgg aacaataact aaagttgtaa aagatgcttt
    14341 gaatatacca gctttaacag gtatgtatgt tgaaaatcca ggagcagata tgttcaaaaa
    14401 ggatgtttat gtagtagaaa cttctgattc tgcagcaggt atgagaaagg cacttcctaa
    14461 gatagctaaa cttgcagtaa aacttgctaa tggagaagaa attggaactc ctaaagatga
    14521 aggatacata gctagaggaa taagagttaa ctacttccat gaagacagag gttctaagag
    14581 agctgttgac atgttagtta agaaaataaa aggtgaacca tttgaaactg aatacccaat
    14641 gccaaacttt gatagagttg acccaagtaa agctgtaaaa gatttatcaa aatgtaaaat
    14701 agctttagtt acttctggtg gtatagttcc aaaaggaaat ccagatagaa tagagtcttc
    14761 ttcagcttct aaatatggaa cttattctat agcaggagtt atggatttaa cagaagagac
    14821 ttatgaaact gcacatggtg gatatgaccc agtgtatgca aatttagatg cagatagagt
    14881 attacctgtt gatgttctta gagatttaga aaaagaaggt gtaattggaa aattacatga
    14941 gactttctat acaactgtag gtaatggtac atctgttgca aactctaaaa aatatgcttc
    15001 tgaaattgga gcagcattag tggctgatgg tgtagatgca gtaatattaa cttctacatg
    15061 aggtacttgt actcgttgcg gtgcaacgat ggtaaaagaa atagaaaaaa ctggacttcc
    15121 agtagttcat atgtgtacag tagtacctat ttcattaaca gtaggggcta atagaatagt
    15181 tccaactata gcaatacctc atccacttgg aaatccagcg cttgacccta cagaagaaaa
    15241 agccctaaga agaggccttg tagaaaaagc attaaatgct ttaactacag aagtagatgg
    15301 tcaaacagta tttgaaaaat aaaaataaca cacacatata ttatatagat aaaaatataa
    15361 acacacacta aaaataaaaa ataactatac acaaaaaaaa taatatagat ttcatgaatg
    15421 gataaattgg agttattcat tcatgaaatc ttaaaaaatg ccaaaataca taaacaataa
    15481 tagaatcaaa tatacaataa aatacaatga ttagagcttt taataagttt aataagatta
    15541 aaaaataagt gttcataaaa tttatggagg tgcacaaaat gacttatcca gttttaaaag
    15601 gggcaggcta tgtacttatt catactccag atatgatagt gcaaaatgga agtacttgta
    15661 cagttgaaag agcaacaaat ccagattcag aatttttaaa agaagtaagt aatcatataa
    15721 gaagttatga agatgtagtt aactacatgc caaatcaagt ttatatagga aatagaagac
    15781 cagaagaatt aagagattta ccaatgccat ggtgtgaaca aaagattgag ggaactagaa
    15841 atggtaagtt tggagaaata atgcctcaag atgagttcat agctttaatg caaataagtg
    15901 atgcatttga tttagtaaaa ttatcacaag aatttattga tgaagtaaag ccaaaaatcg
    15961 aaaataacta ccctgaaatt gcaccatttg taggtaaatt aaagggtgat gatatagaag
    16021 aaggtaaaga attagtagca acacacatag ctgaaggatt ataccatgat ggaaaatttg
    16081 ttggttatgt aaaaagagca catgatgtag atgttaactt aaatgcccat acaatgtttg
    16141 aaaatctagt agtaaaagca tctggagttt tatctgctat tcaaatgcta agacatagca
    16201 aaatagaccc tgctgaaata gattatgtta ttgagtgttc agaagaagct tgtggagata
    16261 taaaccaaag aggtggagga aactttgcta aatcaatagc tgagatagca ggacttcaaa
    16321 atgcaactgg ttctgacaca agaggatttt gtgcagcacc aactcatgca ttaattcaag
    16381 cagcagcttt agtaaaagct ggtatacata aaaatgtaat ggtagtagca ggtggagcaa
    16441 gtgctaaact tggaatgaat gctaaagacc atgttaaaaa aggtcttcct gtacttgaag
    16501 atgttgttgg aggatttgca gtacttgtat ctgaaaatga tggtgtaaat ccagttataa
    16561 gaactgattt aacaggtaag catactgttg gaactggttc ttcaccacaa gcagttatga
    16621 cagcacttat aacttcaggt cttgatagag ctaatttaaa aataacagat gttgatgtgt
    16681 attcagttga aatgcaaaac ccagatataa ctaagccagc aggagcagga gatgttccag
    16741 aagcaaacta caaaatgata ggggcacttg ctgttaaacg tggagactta gaaaagaaag
    16801 aattgaaaga ttttgtttct aacaaaggat taccaggatg ggcaccaact caaggacata
    16861 taccatcagg agctccttat ataggatttt taatagatga tttaactaca ggaaatagaa
    16921 atagagctat gatagttgga aaaggtagtt tattcttagg aagaatgact aacttatttg
    16981 atggagtatc ttttatagct gaaagaaata caggtgttac tgaagagact tcaggaatat
    17041 ctaaggatga aattaagaag ataatagctg aatctatgaa aaaactagca ttagatatgt
    17101 tagaagaata ggggtgagga tatgtcaaaa aaagtaatcg cagatgtatt cttagaagta
    17161 gctaatgcaa tagaaagcgg cgaatttggc aaaaaagtaa aaattggtgt tactacactt
    17221 ggaagtgaac atggtgtaga aaacatggtt aatggtgcac aattagcaaa atctaattta
    17281 tttgatattg tgcttattgg accaaaagtg gaaactgacc ttgaagtagt tgaagttaat
    17341 gatgaaaaag aaatgcatgc aaaaatggaa gaattattag attcaggata tattgatgct
    17401 tgtgttacta tgcattataa ttttccaata ggtgtatcta cagtaggtag agtaataact
    17461 ccagcaaaag gaaaagaaat gatacttgca acaacaacag gaacaagtgc tactaataga
    17521 atagaggcaa tggtaagaaa tgccatttat ggtattgcta cagctaaatc aatgggtaac
    17581 aaatgcccaa aagttggaat acttaatgtt gatggagcaa gacaagttga gaagtgctta
    17641 aaagaattaa aagataatgg atatgacatg gagtttgcgg attcaattag agcagatggt
    17701 ggatgtgtaa tgagaggtaa tgatttactt gtaggtgcac ctgatgttat ggttactgat
    17761 acattatctg gaaatatatt tatgaaagta ttttcttcat atactacagg tggagattat
    17821 gaagctcaag gctttggata cggacctgga gttggagaag actatgatag aaaggtactt
    17881 atagtatcaa gagcatcagg ttctccggta gtagcaaatg ctttaaaata cgcttatgat
    17941 gttgtaaagg gagatataag taatgttgca agaaatgaat ttgcaaaggt taaaaaagca
    18001 aaatttgatg acattatatc ctctcttact aaaaaagaag ttaaagctga aaaagtagaa
    18061 gttaaaatgc cagataagga aattgttact cgtcaaatag ctggtgttga tataatggat
    18121 ttagaagatg cagtatctga gttatggaaa aacggaatct atgctgaaag tggtatgggt
    18181 tgtacaggtc caatagtttt agtaaatgaa gctaaaggag acttagcagt tgaaacttta
    18241 gttaaagctg gatatactgc aaaataagta cattttttat atgtaaataa gaacatatag
    18301 ttataatttt attgattata attatatgtt ctttttattt tatatcttgt caatatttat
    18361 atattaacac aatccattta tttgattctc tagctaattt attatattta ttcaattaaa
    18421 attaagcttt ctaactaaat aaaaactaat gaagtattaa aatgaaattg ataaaatatg
    18481 aaaaaatttt aggaataaag tatctgttag ataaaaataa gattaattag tgatataata
    18541 taattaagat aaaatttatt atttggaggt aaaatcatga gcagagtaaa aaatgtagta
    18601 gaattgttgg aaactaaagg tgttgatgca ctatatctaa caaagaaaac taatgtaaac
    18661 tatataagtg gttttcctga tgaagaagca tatgcagtga tttgcaaaga tggaaacttt
    18721 ttagttactg atagtagata tatggagctt gcagaaaagg tttgcaaaga ttttgaaatt
    18781 ataaattggc ataattttga tagaagtgtg gcaaaggcag ttaaaagtgt atgtgataaa
    18841 gtgggtataa agaaacttgg gtttgaaaga actaatatag tgtttgataa atatgaagaa
    18901 cttaaaaatc tgattgagaa ggataatgga gaattaatac ctacagaaaa tattgtagag
    18961 actttgagat atgtaaaaga caaagatgaa atcaaaaata caagaaaagc ttgtgaaata
    19021 gcggataagg cattagaaga attgattcca catataaaag ctggagttag cgaaattgaa
    19081 ctggctacaa agttagagta ctttatgaaa atgaacggag cacaaaatat agggtttgaa
    19141 actatactga tatcaggagc aaagacttca ttgcttcatg gtaagcctag tgataagatt
    19201 atagaaaaag gtgattttgt acttatagac tatggtgcta tgtataatgg ctatatatct
    19261 gatacaacta gaacttttat agttggagga gcttctgaaa agcaattaga aatatataat
    19321 ttagttaagg aagctcaaaa tgtaggggtt gagaacatga aagctggtgt acatgcggca
    19381 attccagatg ctgagataag aaaagttgtc aaaaaatatg aagactatta ctatcaaggt
    19441 ataggacatg gagtcggtag agatgttcat gaagaacctt tcattggtaa ttatggtgat
    19501 aaaatcatag aagagggatg tataataaca atggaaccag gtatttattt ccctggatgg
    19561 ggtggagtta gaatagaaga tactgttttg attactaaaa atggtccaga aagacttact
    19621 aaattcccta aagatttgat gattttagac aaataattta atttatatat atttttttac
    19681 ataaaatata acataatctc actattaagc tctatttaca tattatagta aagagggctt
    19741 aattttattg tgagaggtga tagtatatat gtataaaaaa cataaattta taaaaaatat
    19801 aaaaaaagcc tggtataaaa ttaaattaat tgatagatgc cttataattg taatggcaat
    19861 attaatgttt caatctatat ataatttatt tgttaatgaa gtaaattcac aagatactac
    19921 aactattgat gtagtagtaa gaaccacttc agcagctata tttgggtatt ttttaagtgc
    19981 taattttata aagagacctt taaggaagta tacaaatact gatgtatctt caaatctttt
    20041 tatagataat aatttatccc caaaaggtca agagtctaat caaaataata taatgaatgt
    20101 caaaaatacc attggattta cttcagaagc tgataattat gaaaagaaaa tacctattaa
    20161 taataatgaa ggttttgaag aaggagaaac tagtgaattg caaattatta tagctactgt
    20221 aatttgtata gtagcattaa cagtactttt tgttgtaaga aattttacaa ctacaacatc
    20281 agcttcttta ggtactattt cacagatgag agattttgtc tcaggatgcg tgggtttttt
    20341 gctaggttgt ccaagtaaac ctgattaaaa aagtattatc aataaaaggt attttaaaaa
    20401 gtatcagtat aataatattt agatttaaat gtatacaatt ataattctat aacattctat
    20461 attgtatttt tatactgata ctctaaacta tactatttat taaaatattt taacattgta
    20521 tttaaacaaa atattatatc tgtataatat aaatttagtt tatatgaata gatgccatat
    20581 actcaataaa aagtttcata ctatgagata tgtattgatt tcttctccaa agaaccccaa
    20641 tatttgcagt aattgcacgt tctaatggta ttgaacagag attttctgta ttttgaaata
    20701 tttctttata caatattgtt gaagccaagt cattttctag taaataacgt atggtagaaa
    20761 gttgatttga gtgtaaaatt atatttggct tagctttttc aagtcttttt gtaataatct
    20821 tatagtgata agaaccttca gataagatta caaaaggtac attttttaac atataattcg
    20881 atataatagg atgttttgcc aattcatttt tgggatttgt aactaagtat aattctgttt
    20941 tatagattgt ctttgaatct atatcatcat aaatatcact gtcaattata ccaatacaaa
    21001 aatcaagtgt agattcttca atcattttag ctccaacaaa tgttggaact tcaaaaattt
    21061 taagctctat atctggataa attacattaa atctaggaag tatttttgaa agcaaaaacg
    21121 tacctaaaac tgtaggaata cctattttga gagaagcttt tctctttttt cctaaatcaa
    21181 gtgcgtcaca ttgaaaatcc tcaaattgtt ttataaaatg ttttgacttg tctaaaaaaa
    21241 tttttccttc aggcgttaac tctattttat tacctattct gtaaaaaagt tcaaagccaa
    21301 gttctttttc taattcttta attgctaatg ttatggatgg ttgagaaata tgaatacttt
    21361 ccgcagcctt agtcatgttt ttatatttac agacagtttg aaaatagtat aaatagttta
    21421 tattcatttg gtattagttc ctttcattta catattagtg acaagtatat aattaacaat
    21481 agcataagtt ttgtatattg ttgtaaaaaa atagaatagt tttaaactat catagcataa
    21541 gtttttgata ttttcaatct attaagaata gtgctattat taaattaaca aaagagaata
    21601 gctggtatgg tttagagtaa atcaatctat attacagtta tatcaacgaa tatcaaaaaa
    21661 ttatctatta aaaaataaaa attattttta caattaaatt gttaattaaa tcataaagaa
    21721 aaaagtgata ttaacaagat aaaatttttt taatcagaaa tgttaattta ataacaaaat
    21781 agagtattgg ggagaaagga gaaatatatt ttttaataat atttgttaat ttaataacaa
    21841 aaatgaaagg gagtgattta gtgaagtttg aattgatgga ttttttaatg aatccttttg
    21901 tccttatgtt tgctgcagta attacaggaa ttttatttgg aaaaattaaa tttgggaagt
    21961 ttaattttgg ggtatcagga gcattattta caggattatt tattggatgg cttgcatata
    22021 gcttggggaa tctaataata gcaaaagggg aaacagcagc aggatataag gcagcaactg
    22081 taatgatggg gaatggaatt atttcttctg acttctttga tttcttttta ataatatttg
    22141 ttgcagcagt tggtctattg gcagcaaaag atatgaaagc tgtattaaag aagtatggag
    22201 caagatttgt aattttagga gttcttataa cttttatagg tggctctatg acttatgcaa
    22261 tgactttact atcaagtgat aaaggaagta gtgcttatga agtttctggc gtttacacag
    22321 gagcattaac aagttcgcct ggattagctg ctgctttaga aacagctggt aaacatgcag
    22381 aagatgtatc aaaagaattt gaaaaagcat caataaaaga taaaaaagaa attttaaaag
    22441 tagtcgaccc agaaggcaaa ttggatgtga atacaactac atcactgact caagagcaaa
    22501 tagataagta tattgcatat gctgaagctg gtgttggtat aggtcatgca gtcgcatatc
    22561 cttttggagt tttaatagta atcttaggtg taaatttcct tccaaaatta tttaggatgg
    22621 acctaaaaga agaaagaaga aaatatgaga aggaaatgaa ggaagcaaga gatagtgttt
    22681 ctggtaaaac gataccagaa gttccattta atataataac atttttcttg acatgtttag
    22741 ctggatactt agttggagga atacatgtat ttatgggacc actagggtac ttcacactag
    22801 gtgcaacagg aggttcacta attgtatctc tagttcttgg atatataggt aagatagggg
    22861 tagtaaattt cagaatggaa gaaaaggttt taaatatttt aaaacaaata gggctagtat
    22921 ttttcttagc aatagttgga ttaagatatg gtggaaaagt agttgattca attatgacat
    22981 ctggtatgca cctagcctta gtagcaatag cagtaggtgt tacagctatg atgataggat
    23041 tcttagttgg caaatacgta tttaaattaa attggatttt attatctgga gctgtctgtg
    23101 gtggtatgac atcaacacca ggtcttggag ctgctgttga tgctcttgat agtgatgacc
    23161 cagcagcagg ttatggcgct acgtatccat ttgcattatt aactaaagtt atattggtta
    23221 tagttttaca caaacttcca atgtaaataa gattttatat ggggggatat ttatgaataa
    23281 tgaaggagca tttgaagaat taagtggaag attaagaaat aaagaattgt gtgatttaat
    23341 aatgaatgca gatgaagctg ctaaaattat agaggatggc atggttattg gagttagtgg
    23401 atttacacct tcaggctatc caaaagcagt accattagca gtttcagaaa gagctaaaag
    23461 tggagaaaag ataaaattaa ccgtatattc aggagcatct ttaggtccag aagttgatgg
    23521 agcatggtca gaagcaggta taattgaaag aagacttcct tatcaaacta attcaatact
    23581 tagaaataat attaataaag gtgttgttga ttatatagat atgcacctaa gtcattctac
    23641 tcaattttta aattatggaa ctatacctaa agtagatgta gctatagtag aagcacttgc
    23701 aataactgaa gaagggaata ttataccaac tagtgggata ggtaattctc catcttttat
    23761 aaaaagtgca gataaagtaa tagtagagat aaatcttgca aaaccaatgg aaatggaagg
    23821 tatggcagat atatatatta cggaaaatcc accaaataga aaaccaatag aaataaatca
    23881 tcctaaggat agaattggaa caacatatat accttgtggt ttggataaaa ttgcaggagt
    23941 agtaattacc aatatgcaag ataagacccg tccattgggg gttgtagatg aagcttcgaa
    24001 aaaaatatca aataatatta ttgctttttt aagagaagaa gtaaaggcag gcagattatc
    24061 aaagaattta cttcctcttc aatctggtgt aggaagtgta gcaaatgcag tattatatgg
    24121 attatgtgaa tctgaatttg aaaatttaac ttgttataca gaggttgtac aggactctat
    24181 gttggattta ataagaatgg gtaaagttac aatggcatct actacatctg taagtccatc
    24241 tccagaagga ttaataaaat ttgaaaaaga tattgatttt tttaaggata agattatatt
    24301 aagacctcaa gaaattagta acaatccaga aatagccaga agaattggtg taattgcaat
    24361 gaacactgca attgaagttg atatttatgg aaatgtaaat tctactcaca taatggggtc
    24421 aaagatgatg aatggaattg gtggttctgg tgattttgct agaaatggag caataactat
    24481 atttagtact gagtcaattg caaaaaatgg tgatatatca tcaatagtac ctatggtatc
    24541 tcacgtagac cacactgaac atgatgtaat ggtaattgta acagaacaag gatatgctga
    24601 tttaagaggt cttgcaccta gagaaagagc tataaaaata atagaaaatt gtgcccatcc
    24661 agattataaa gaacaactta gggattattt aaatagagct tgtaaaagtg gagcaaaaca
    24721 aacacctcac atattggacg aagctttatc atggcatagt aaatttatga gtacaggtac
    24781 aatgaaaaag gctgaaactt ttaaaagtgc attataaaat atttaataaa ttggaggtag
    24841 attttaaatg gaaaaagcag tggaaaactt tgaagattta agtaaggaat acattaatgg
    24901 ttatattgag agagcaagaa aagctcaaag agagtttgaa tgttatactc aagaacaagt
    24961 agataaaata gtaaaaatag ttggaaaagt agtgtattat aatgctgaat atttagctaa
    25021 acttgctgta gaagagactg gaatgggagt atatgaagat aaggtagcta aaaataaaag
    25081 caaagcaaaa gttatatata acaatttaaa agataaaaaa tcagttggta taattgatat
    25141 agatagagaa actggaataa caaaggtagc taaaccagtt ggagtagtag cggcaataac
    25201 tccttgtaca aatccaatcg ttacacctat gagcaatgca atgtttgcac ttaagggaag
    25261 aaatgcaatt attatcacac ctcatcataa agcaattgga tgtagtacaa aaactgtaga
    25321 gatgattaat gaagaattag aaaaaatagg agctccagaa aatttaatac aaatacttga
    25381 ccaacaatca agagaaaata caagaaattt aatttcatca gcagatgtag taattgccac
    25441 tggaggaatg ggaatggtaa aagctgcgta ctcaagtgga aaaccagcac ttggtgtagg
    25501 ggcaggaaat gttcaatgta tcatagatag agatgtagac attaaagaag cagtacctaa
    25561 aatcatagca ggaagaattt ttgataatgg tatcatttgt tcaggtgaac agtcagtaat
    25621 agtagcagaa gaaatgtttg ataaaataat ggatgaattt aaaaataaca aaggttttat
    25681 agttagagat aaagtacaaa aagaagcttt cagaaatgct atgtttgtaa ataaatctat
    25741 gaataaagat gcggtaggtc aatcagttca tacaattgca aaaattgcag gtgttgagat
    25801 accagaagat acaaaaataa tagtaataga agctgatgga ccaggagaag aggatattat
    25861 tgcaaaagaa aaaatgtgtc cagttatatc tgcatacaag tataaaagtt ttgaagaagg
    25921 tgtagctatt gcaaaagcaa atttaaatgt agaaggaaaa ggacatagtg tatctataca
    25981 ttcaaataca gttaaaaata tagaatatgc aggagaaaat atagaagtat caagatttgt
    26041 tattaatcaa tgttgtgcta ctagtgctgg aggaagtttc tttaatggtc ttgcacctac
    26101 taatactcta ggttgtggtt cttggggaaa taacagcatc tctgaaaatc ttgattataa
    26161 gcatctaatt aatatttcta gaattgctta ttatatgcca gaaaatgaag tccctacaga
    26221 tgaagaactt tggggataaa atttagacaa aaaatattca ttctaaatta aagtaggaat
    26281 atattttaat ttagaatgaa tttaagacat aaattaaatt taaattagtt tattggacta
    26341 aatttaaaat attaagagac atatagaaga aggaagtatt ataatttaaa ataaataaaa
    26401 aaatctataa aagagaagga gtggttttat tatggcatta atgacaggag ctcaatatat
    26461 tgaaagtttg agaaaattaa atactaaggt ttatatgttt ggtgaagagg ttaagaattg
    26521 ggttgaccat cctatgatta gaccatctat aaattgtgta gcagcaactt atgacttagc
    26581 tcatgaccca gaatatgcag atttaatgac agttacttca aatatcacag gtgaaaaaat
    26641 aaatagattt ggtcatcttc atcaaagtgt tgatgatttg ataaaaaaag taaaaatgca
    26701 aagactatgt ggtcaaaaaa cagcttcttg tttccaaaga tgtgttggta tggatgcgtt
    26761 taatgcagtg tattcaacaa catttgagtg tgataaagcc catggaacta attatcatga
    26821 taattttgta aaatacttaa cttatataca agaaaacgat ttagtagttg atggagctat
    26881 gactgaccct aagggagata gaagtctatc acctagtgct caacctgacc cagatatgtt
    26941 ccttcatata gtagaaagaa gagaagatgg gataattgta agaggagcaa aggcacatca
    27001 aactggttca ataaattcac atgagcacct tataatgcct actataagta tgactgaagc
    27061 agataaagac tacgctgtat catttgcagt tccttcagat gctgaaggag tgtttatgat
    27121 ttatggaaga caatcttgtg acactagaaa attagaagaa ggtgcagatg ttgatttagg
    27181 aaataaggag tttggaggtc aagaagcttt agtagtattt gataatgtat ttgttccaaa
    27241 tgatagaatt ttcttatgtg gagaatggga tttctctggt atgttagtag agagatttgc
    27301 aggataccat agacaaagtt atggtggatg taaagtagga gtaggtgatg taataatagg
    27361 agcagcagct ttagcagctg attataatgg agcaaacaaa gcttcacata taaaagataa
    27421 actaatagaa atgactcacc ttaatgaaag cttatattgc tgtggtatag catgttcatc
    27481 agaaggtcac aaaacagaag ctggaaacta tcaaatagat ttacttcttg caaatgtgtg
    27541 taaacaaaat gtaactagat ttccttatga aatagtaaga cttgcagaag atatagctgg
    27601 agggcttatg gttactatgc cttcagaaaa agactttaaa tcagacctta aagttggaac
    27661 aagtggaatg actattggcg aagtatgtaa caagtatttt aaagcttctt cagtggcttc
    27721 aacagaagaa agaatgagaa tattaagatt cttagaaaat atatgccttg gttcatctgc
    27781 tgttggttat agaactgagt caatgcatgg ggcaggttca ccacaagctc aaagaataat
    27841 gatttcaaga caaggaaaca taaatcaaaa gaaagaatta gctaagaaaa ttgcgggaat
    27901 aaaaaaagag gaagctttaa atttataaaa agttgatata taaagggaaa ttatatatta
    27961 atgtgtgtta attaatgaaa aaatatgtag tataagagat agttataaaa ttatggtggt
    28021 ttttagctaa gtaaagaaat ttttaataag gagaatttac acatgacctg tggagttaga
    28081 ttttgtgggg gctgtaaccc tagatacgaa agagggaagg ctcttacaat aatcaaagag
    28141 cacttcaatg gtagggtaga ttttagtata gcacaagaga acgtcgagta tgatttgtta
    28201 cttataattg gaggatgcgc aactctatgc gcatcctatc aacaatataa agtgaaaaat
    28261 gaatgtgtta agatgtggga ttttagccat atagaaagag ttataaatgt gattgaatca
    28321 gcaatttgtg aaacttaaaa aagctaaatg gggggatttc attgagttgg caagaattgt
    28381 atcaaagtaa attatgtagt gctacagaag ctgtaaaaca gattaaaaac ggtgatactg
    28441 tagtatttgc acattgtgta ggtgaacctc ctgcactagt agaagctatg attgaaaatg
    28501 ctgaacaata taaagatgtt gagattaaac atatggtaag cttgggtagt ggtggatata
    28561 ctgctaaggg aatggaagct cattttagag taaatccaat gtttgtaagt ggaaatgtaa
    28621 gaaaggcaat tgaaaatgga gatggtgatt ttacacctgc attcttccat gaagtaccaa
    28681 agttgcttag agaaaaaaga ttaaaatgtg atgttgtttt agcacaggta actccaccag
    28741 atgaacatgg gtattgtagc ttaggaacat cagttgatta tacttatgaa gccattaaaa
    28801 ctgctagaac agtaattgtt caagtgaatg accagtttcc tagaacctat ggtgaggtag
    28861 tccatgtatc agagtttgac tatatagtgg aaaaatcaca acctttattt gaactacaac
    28921 ctgcaaagat tggagaagta gaagaagcaa ttggtaaaaa ttgtgcttca ttaattgaag
    28981 atggctctac tttacagcta gggattggtg ggataccaga tgcagttatg ttatttttaa
    29041 ctgataaaaa ggatttaggg attcattcag aaatgatttc agatgggact ttggcccttt
    29101 atgaaaaagg tgttataaat ggtaaatata aaaattttga taaagaaaaa atgacagtta
    29161 ccttcttaat gggtactaaa aaattatatg actttgcaaa taataaccct gcagtagagg
    29221 taaaaccagt agactatgtg aatcatccag caattataat gaaacaacat aagatggttt
    29281 ctataaattc tgctatacaa gttgatttaa tgggacaggt agttgcagag gctatgggac
    29341 ttagacaatt tagtggtgtt ggaggtcaag ttgactttat acgtggagtg tctatgggtg
    29401 aagatggaaa ggcaattata gctatgcctt caataactac aaaaaaagat ggtacagtaa
    29461 tttcaaaaat cgtatctatt gtggatgaag gtgcacctat aacgacatca agaaatgatg
    29521 ttgactatat tgtaacagaa tacggtatag cagaattaaa aggaaaatct cttagagaaa
    29581 gagcaagaaa tttaataaat atagctcatc caagtgtaag agaaagtcta gcagtagaat
    29641 ttgaaaagag atttaaggag aaatattaat aatagagggg tgttaataat ggaagcactt
    29701 agagtagttc caaagatatt ttactttgat acatttaaag aatttaatga agaatttaaa
    29761 ataggaaaaa atgatttagt aattactaat gagtttatat atgagccata tatgaaacct
    29821 cttggaatag atacaaattt aatttttcaa gaaaagtttg gaacaggtga accatctgat
    29881 gaaatgatag actccatgac aaaggaaatg aagaaataca attttgatag aattattgca
    29941 tttggaggag gaacaatagt tgatatatgt aagatattag cacttgatgt tccagaaaag
    30001 tctattgatt tatttgaagg agaagtatca cctaaaaaag taaaagagtt agtagtagtt
    30061 cctacaacat gtggtacagg tagtgaagta acaaatgtag ctattgcaga gttaaaatct
    30121 aaacatacta aaaaggggct tgcagtagaa gaaacatatg cagactatgc agtgttaatt
    30181 ccagagacag taaaagggtt accttacaaa ttctttgtta caagttcggt agatgctctt
    30241 atacatgcta ttgagtctta tctttctcca aaagcaagtc catttacaga gatgtattct
    30301 ctacaagcaa taaaaatgat tatggatggg tataagaaga tagttgataa aggagaagaa
    30361 gagagattta atcatcttag agactttgta cttgcatcaa attatgcagg aattgctttt
    30421 ggaaatgctg gttgtgcagc agttcatgca ctatcttatt caataggtgg agctttccat
    30481 gttgcacatg gtgaagcaaa ttatcagttc tttactgaag tatttaagat gtattctaga
    30541 aaaaaaccta atggaaaaat tataaaatgt acaaaaattt tagcagatgc ccttgaatgt
    30601 gaccctaact gtgatgttta tggagaatta gaaaagtttt taaataaatt aatagctaaa
    30661 aaagctttga gagaatatgg aatggttgaa agtcagatag atgaatttac agatagtaca
    30721 atagcaaatc aacaacgact acttgctaat aattatgtag aacttagtag agaggaaata
    30781 agagagatat ttgcaaatct ttattaatac aattttttat ttatatgtat agtcaacata
    30841 aacaatgcta attatattta tgtacaaata aaaataaggg aacttaaatt ttaattaaag
    30901 ttaagttctc ttatttttat atggagttaa atataagtat atttttaatt taaaatatgc
    30961 ttatatttaa gtctattact ttatttgaaa caatttgtag aatttcaaat tccttgacag
    31021 taataagtaa gtaattgtat aatcaaactg caatatatta ataatattag tgaaaatgaa
    31081 aggattataa aatatgtata aatcagaaaa tttttcaaaa aaatctgtat taataaattc
    31141 atttttaagt aaatttttaa aaataattgg atggggtttg gtaagcttat ttacattatc
    31201 agccttagta ctttcaacta tttccattat aattggatgg gctgtaatac ttcctattca
    31261 agtatgtgca gtatttttac ttataggagg agtttgtatt tttaaaggta agagattagg
    31321 agaccaaatt tctcgttata aaaaatattg tacaattata aacaatagaa atattattcc
    31381 agtagaactt attgcagaaa acacatctaa atcattaaat tttataataa aagatgtaca
    31441 aaagatgata gacaaaaact actttataaa tacttatatt gataaaagaa ataatcagat
    31501 tgtgttaaca aatgaagatt ttattccacc aagatatgaa gatgtagcat atgaagtcaa
    31561 agaagaagaa aagactgatg aatccaatga agttgataca attataaata aaggaatgaa
    31621 ttatctaaca caaataaaag aagctaataa aaatattaaa tcagaatcaa tgggcaataa
    31681 aattgtacaa gtagaagatg ttacaagtaa aatatttgat gttgtaaaac atgacccatc
    31741 aaaacttact caaatacaaa aatttatgga ttattatctt ccaaccactt taaaactatt
    31801 aaattcatat catacattgg aagaacaagg aattgataga gaaaatataa caacaactat
    31861 ggaaagtatt gaaaatacaa tgaatacgat tgtagtagct tttgaaaatc aattggacta
    31921 tctgtttgaa gatgaagcca ttgatatttc tacagatatt actgttttag agaatatgtt
    31981 agtccaagaa ggattaacga gtggtaaatt ttaacttcaa tagaaaaaat attctgttat
    32041 ttttaaacaa ttaattagtc ataaagtata aaatgtgtat tatataagtt aatcagtact
    32101 ttatgaagga agaggagaga aagatacaat gaataattta gatgatatac cagttatgcc
    32161 aactttgaca cttgacccat ttggagaaga atcaaacact aatgatatag ataattctga
    32221 cttattaatg aaaaaggatg aaaaagaccc agaagaagaa aaactgtctg aatctgaacg
    32281 caagatggta aaggaatttg cggaaaaaat agatattaca aatacaaata tgattttgca
    32341 atatggagct ggtgctcaaa aaaaggtagc aagtttttct gaaacagctt taaagagtgt
    32401 aaaaacaaga gatttaggag aagttggaga tatgcttaca aatctagtta ctgatttaaa
    32461 agcattttca gcagatgaaa aagaacaaag tggtttttta ggaattttta aaaaggcaaa
    32521 taataaaatt tcaaatttaa aaactaagta tgatagtgca gaggtaaatg tggataaagt
    32581 aagcaaagag cttcaaaagc atcaggttaa aatattgaaa gatatagcaa tgcttgataa
    32641 gatgtatgaa ttgaacttag cttactcaaa agagcttact atgtatatta tagcaggaaa
    32701 acaaaaatta aaggatatga aagaatatga gatgccaaag ttgagagaaa aagctcgttt
    32761 atctggttca acagaagatg ctcaatctgt aaatgatatg gtttcacttt gtgacagatt
    32821 tgaaaagaaa attcatgact tagaattaac tagaatggta tcgcttcaaa tggctcctca
    32881 gataagattg gttcaaaata gtaataatct gatggcagaa aagattcaat caactatagt
    32941 aaataccatt ccattatgga aaaatcaaat agtgcttgct cttggaattt ctcacttaaa
    33001 tcaagctatg aaagcacagc gtgaagttag taatatgaca aatgagcttt tattaaagaa
    33061 tgcagaaact ttgaagatgg gaacaataga aacagcaaaa gaatcagaaa gaggaattgt
    33121 agatatagac acaattaaga aaacgaatca atctctaata tctactattg atgaggtagt
    33181 taaaatacaa catgatggta gaataaagag acaagaagca gaagttgaat tatcaaaaat
    33241 agaaaatgaa cttaaaagta agcttcttga atttacagtt aaataaaaat tatactaata
    33301 taaaaagaga ctgtctcaaa atagagataa gtctcttttt cattgtttaa atgattaaag
    33361 tatatttata ttataaattt ctattatctt ttaacataac atcatgagct ccaccttcaa
    33421 ctatactagt agaagataca agtgtaagtt tagcattttt ttgaagttca ggaatgctaa
    33481 gtgctccaca gttacacata gtagaacgaa ctttacttaa agaaagagtt acattgtctt
    33541 tcaaagaacc agcataaggc acataagagt caacaccttc ttcaaaagaa agtttcttat
    33601 ctccaccaag gtcatatctt tgccagtttc tagcacgagc agaaccttct ccccaatact
    33661 ctttcatata actaccattt atattaactt tgttagttgg actctcatca aaacgagaga
    33721 agtatctacc aagcattata aaatctgcac ccatagctaa agctaaagtt atatgatggt
    33781 cataaacgat accaccatca gagcaaattg gaatataaat acctgttttt tcaaagtatt
    33841 cgtctctagc ttgagcaact tcaattatag aagtagcttg tccacgtcct ataccttttt
    33901 gttcacgagt tatacatata gaaccaccac caataccaac tttaacgaag tcagcaccag
    33961 cttcagctag gtaaaggaat ccttcgcggt caactacatt tccagctcct accttaactg
    34021 tatcaccata tttttcacga atgaaatcaa gtgttatttt ttgccactca gaaaaacctt
    34081 ctgaagaatc tatacataaa acatcagcac cagcttcaac taaagcagga acacgttcag
    34141 caaagtctct agtattaata ccagctccaa ctacatatct cttagaagaa tctaaaagtt
    34201 caagtggatt ttctttatga gaagagtaat ctttacggaa taccatatac ataagattac
    34261 cattatcatc aagtacagga agagaattaa gtttgtggtc ccatataatg ttgtttgctt
    34321 cctttaaagt aacatctttg ttagcataaa ctatagatga cataggagtc ataaattcac
    34381 taactttagt atctaaatcc atacgactta tacgataatc acgacttgca acaataccca
    34441 ataatttacc agttgaagtt ccatcttcag taacagctac tgtagaatgt ccagtttttt
    34501 cttttaagtc aagtatgtct tttaatgtgt tatcaggttt aatatttgaa tcacttacaa
    34561 caaaaccagc tttgtgggat ttaacacgtg ctaccatagc agcttcattt tcaatagttt
    34621 gagaaccgta tataaatgaa ataccacctt ctttagcaag tgcaatagcc attttgtcat
    34681 cagaaacaga ttgcataata gcagaagtca aaggtatatt catataaata tctgcttcct
    34741 cgcccttttt aaatttagta acaggtgttt ttaaacttac attagcaggt atacaatcag
    34801 tagaagagaa acctggtaca agaaggtatt cactgaaagt atgtgatggt gtatcaaaat
    34861 aaaacgccat tttttaatca ctccttatat ttttatactt tttataattg atagtattaa
    34921 ttataactta ttctttaatt ttattaaagt attttgtcaa atattgagat ttttgaaaaa
    34981 tttaaactat tttaattaaa tttgtttaat atatattgcc ttatagggta aagttgtata
    35041 ttaaataatg tttagtgttt aatagtagct aatttaaaat taatctttag tgattcatat
    35101 aattacattt gtatagttta tattgataat attactagag agtgtataaa cctcaaaaat
    35161 acagataaat taaatctata ttagtatatc caaaagtaca tttaataaat ttatttaact
    35221 gaattattat tttcatttct attaaattta aatattttat aaaaatagta ttatttacaa
    35281 aatcatatac tccaaaatac tacataaata aaattaaaca aaaactaaaa tgacaaatgt
    35341 cattatctaa agtgacatag aaacggtttc ttaaagttgt tactataaaa tataaactct
    35401 ataataaaag tataacaaaa gggaatcata tcgatataga atataattca agaggaggta
    35461 aaattatgag tagttctaat caatcgacaa taaagacatc tatacagcga gtagggaaat
    35521 ttttaagtgg tatggtaatg ccaaatatag gagcttttat agcatggggt cttataacag
    35581 cattatttat accaacagga tggatgccta atgaaaaatt gagtactata ggtgacccaa
    35641 tgataaaata ccttttacca ctattgatag cttatactgg tggtaaagca atagcaggac
    35701 aaagaggtgg cgtaataggt gcagcagcag ctatgggagt aattgttggt gcagatatac
    35761 caatgtttat cggagcaatg ataatgggac catttgcagg atgggtaatt aagaagtttg
    35821 ataaatttgt agatggaaag ataccaacag gatttgaaat gttagtaaat aacttttcaa
    35881 taggtataat aggtatgctt cttgcaatac taggatttta tgcaattgga ccagcaatag
    35941 tagcagggac agctcttata gaatctggag ttcaatttat agttagcaaa agtttattgc
    36001 ctctagtttc agtatttata gaacctggaa aagtattatt cttaaacaat gcaataaatc
    36061 atggtatatt agggcctata ggtatagctg aggcaaaaga agcaggtaaa tctataatgt
    36121 tcttactaga aagtaaccct ggaccaggtt taggagttct attagcatat tggatgttta
    36181 gtagaggaag tgtaaaacaa tcagcaccag gagctgtaat aatacatttc tttggtggta
    36241 tccatgaaat ttacttccca tatattttaa tgaatccagt tttaatattg gctacaatgg
    36301 caggtggagc agcaggaata ttgacttttt caatattagg agctgggctt gtagcagcac
    36361 catcaccagg aagtatattt gcacttatgg cactagctcc aaagggagga ttacttccag
    36421 tattagcagg agttgcagtg gcaacagttg tatcattctt agtggcagca ccatttgtta
    36481 agagagcttc agcaaatcaa agtgaagaag acagtacttc tttagaagaa gctaaagcaa
    36541 aaatgagtga tatgaaatct gcaagtaaga actctgagaa aaatattgac gaaaaacagc
    36601 ttgaagtaaa tgagattaag aagattgtat ttgcatgtga tgcaggaatg ggttcgagtg
    36661 caatgggagc ttccagattt aaaaatagaa taaaaaactt agacttaaat atagaaatta
    36721 caaattcatc tgttgataat cttccagatg atacacaaat agtagtaact cacaatacat
    36781 tagttgaaag agttgctaag aataattcaa gtgttgagat agtttcaata aacaattttt
    36841 taaatgaccc aaatttagat acattgttta aaagattaga atctaaataa aaataaaaag
    36901 taccactaat taggagtgga taatttgaaa aaaaagaaga ttacatctag gcaaaaaaag
    36961 ataatactaa tgatagtaga aaattcaaag aaaaacattc caataactat ttctgagatt
    37021 gcagggactt tagagttaag ttcaagaact gtacttagag atatgtctgg aattgaaaaa
    37081 tggtttgatg aaaatgattt taactttgta aaaaaaccag gagtgggatt gattttagag
    37141 gaaaatatag aaaatcaaaa ctttataatt gagttgttag aagaagaaaa aatagaaaaa
    37201 gaatacagca aggaagaaag aaatttaatt atattatcaa agctactagt ttctaacgag
    37261 ccagtaaaat cctattattt tgcaaaaata ttaaaggtat ctgaaggggt actgaataat
    37321 gattttgcct tagcaagtaa atggttggaa agatttgata ttgagcttgt tagaaaacca
    37381 gggcttggtg tctatttaaa aggtcaagaa aaaagcttta gagaggcata tgtaaatctt
    37441 atatacgatt cattcaatga aaaagaaata ctagatatgg tcagaaatat aagtgaaaat
    37501 atacaaacag ataaagcaat agaaatttta agtgaaaata gacttttaaa tttaatggac
    37561 aggtgcataa taagaaaagt tgaagctaca ttaacaaaga agctttcaga tttagatgta
    37621 aatttagctg atagtgcata tatagggctt gtagttcata tttcattagc cttacagagg
    37681 ataaaaaatg gtgaaaatat aactatggat aaagagtttc taaaagaatt atctataaca
    37741 gaagagttta aattagctaa agaaatcgta aaaggtatgg aaacagattt taacatggat
    37801 ataccagtag atgaggttgg atatataacc atgcatataa gaggtgcaaa gcaaaggtca
    37861 tcttcaaacc ataaggcttt aaacttagat gatatagaaa taatggaaat tacaaataag
    37921 atgatagatt tggcggaaga tgaatttaaa ataagtttaa aaaatgacga gaggttattt
    37981 aaagacctag caaatcactt agggccttct ataaatagat tgaatatggg attagaaata
    38041 agaaatcctc ttttagatga aataaaaagc aagtattcat atgcctatga tggagttgaa
    38101 aagatttcta gaattataaa agataaacta aatataaatt caatacctga atcagaaata
    38161 ggatatattg caatgcactt tgcatcagcc atagaaaaaa atcttatgat gaatactaat
    38221 ataaatattg ttgtggcatg tcccactgga ataggtactt caagattctt atcaactaag
    38281 attgaaaata aatttcctaa tttaaatata cttgaaacca tatcagctat aaacatagat
    38341 gaagagtatt taaaggaaaa agatgttgat ttaatagtgt ctacagttga gttaaataca
    38401 agtttaaatt atatatgtgt aggtccattt atgagtttag atgatgaaca gataatcaag
    38461 gaaaaaataa aatctatagc tcaaaataaa ttaatcaatt taaatgcgaa aaatgatact
    38521 aagagtaaga ataaagtata tgaacagata acagaaagta tgaatatagg aaaagatatt
    38581 cttcaatttt tagaggaaat tagatttgaa aaatttgaaa gtaaagattt aagtgagctt
    38641 attgaagact catcaagaat atttgcaaaa tctagtgaag atataatctc tataaaagaa
    38701 tcgttaaaag aaagattaaa aatctcaatt ccatatatag aagaatcaaa aattctattg
    38761 ttacattgta tgagtgaaag aatagatatt atgaagttat caataataaa actagagaat
    38821 agaatcgtgc tagattcaaa tgaagaaatc gacaatgtag tttttatgtt acttcctaaa
    38881 aattcaccaa gttatcaaag acaaataatg agtgaaataa gtggttcatt aatagacaat
    38941 ataattttta ctaataagat aaataaattc tctatagaag agatggcatt agaggtaaaa
    39001 gatatagttt ttaattttta tacaaacaga ttaaaagcat ttatagataa ataaaattaa
    39061 tattaaaaag gaaggttgat actatgagta aagtattgaa tgagaataat atatttttag
    39121 ggttagatag tgtttcaaag gaagaagcta taactttagc aggaagaaaa ttagttgaaa
    39181 atggatatgt aaaagaagaa tatataccag caatgttaga aagagaaaaa gtaatgacta
    39241 catatatggg aatgggagtt gctattccac atggtgtaaa tgaagcaaaa aaagaaatat
    39301 tatcttctgg aatagttata ttacaattcc ctaatggtat agattttgat ggagaaaaag
    39361 catatttatt aataggaata gctggtgttg gagatgaaca tttagaaata ctatctaata
    39421 tagcagtagt tttagatgat gacttaacag aaagactaaa aaattcaaat gacaaacaag
    39481 cttttatgga agcttttgcc aactaatctt aggagggatt taaaatgaaa aaggcaattc
    39541 agtttggagc aggaaatatt ggaagaggtt ttattggagg cttgttagtt aagtcgggtt
    39601 atcatgtagt atttgctgat gtaaatgagg atatattaaa ctcaataaac aaagataaaa
    39661 agtatactat acacataaga gatgtagaat gtatagatga agtaattgat aatataagtg
    39721 cggtttcatc tataaaagaa gaaataatag atgagattgt acaggctgaa ataataacta
    39781 cagcagttgg acctttagtt ttgactaaaa tagcctctac aattgcaaaa ggtataaagg
    39841 ctagaaaaga aaagggatta acaagtaatc taaatataat agcatgtgaa aatgcaatat
    39901 acgcaagttc ttctttaaaa gaagaggtac ttaagtattt aaataaggaa gaagtagaat
    39961 atttagagat gtatgttggt tttccaaact gttcagttga tagaatagtt cctcctggta
    40021 aaaacgaaaa tcctcttgat gtaacagttg aaaattttta tgagtggaat gttgaaaaac
    40081 aaggatttaa aggggaaata ccaactatag ttggaatgaa tttagctgat aatcttatgg
    40141 cttatataga acgtaaattg tttacactga atacaggtca tgctataaca gcttatatag
    40201 gatatttaaa aggatataag actatagaag agagtataaa agataaattt atctgtgata
    40261 tagtcaaaag tgcaatggta gaaagtggag aaggattgat taaaaaatac aattttgact
    40321 cagaagtgca ctataaatat attgataaaa ttttaaatag atttaaaaat ccatatctta
    40381 atgatgatgt attaagagtc ggaagggaac cattaagaaa actaagtgat aaagatagat
    40441 tgattaaacc tttaatgaca gcaaaatcat atggattatc agttgataat ttgattcttg
    40501 gaataggtgc agcgcttcat tataataata gtgaagatac tcaaagtgta gaattacaag
    40561 agttgataaa gtctattggg gtaaaaaaag ccgttgctaa aatagctaat ataagcaatg
    40621 acgaagaact tttaaataat atcgaaaaaa gttatatatt tatgaaaaat ttataaattt
    40681 acttgaaaaa aagtagttct gataaagtaa ctataatata ttattctaca cagtttgaat
    40741 tatttgttga ataatagaga attataatat ataattaaaa ggaataaatt aatatattta
    40801 cctgtatatg tttgataata tggttcaaat gtttctacta agctaccatt aatagcttga
    40861 ctacaggagt gaagaagata tagtttatac ttattttaaa ttatatatta agttaattac
    40921 tttgaatttt aagctcctgt ctatgatata gacaggagct tttttagtat tttaatataa
    40981 aatacttaca agaatagata gcaaaattag aacaaatata atttttttat taatataatt
    41041 ttagaaaggg ctaggtggaa gttcaatgaa ggctttacaa gaaaagatat tgagagaagg
    41101 cagtgtttca ggaaatgata tactaaaagt tgatagtttt ttaaaccatc aaattgatgt
    41161 agctttttta aatgaaatag gaagagaatt taaagagaga tttaaaggag aaaaggtgga
    41221 taagatattt acaatagagg cttcaggaat agctatagca tcaattgttt cacagtattt
    41281 tgataatgca cctgtagtat ttgcaaaaaa atcagaatct aaaaatttgg ataaagatgt
    41341 atatgaaact aatgtatatt catttactaa ggcaagagag tattcagtta aagtttctaa
    41401 aaagtacata aacaaaggcg aaaatatatt gatagtggat gattttttgg caaatggaag
    41461 agctgctctt ggacttaaag atttaattga gcaagcagaa gctaacttag ttggagtagg
    41521 aattgtcatt gaaaaaggat ttcaagctgg aggagcactt ttaaaggcta atgatgtaag
    41581 attagagtct ttggcagtag ttgaatctat agataatgga actgtaaaat ttaggtaatt
    41641 tatgatatta tatacttgtg tttagcacat attttaacta tgtaattatg gaggattttt
    41701 tatgagattt tttatagaca cagccaatat tgaagaaata aaagaagcaa atgatttagg
    41761 tgtaatatgt ggtgtaacta ctaatccgtc tctaatagct aaagaaggta gagattttat
    41821 agaggtagtt aaagaaataa gtgaaatagt agatggacca ataagtgcag aagtaataag
    41881 tttagaacat aaaggtatga tagaggaagc agaaaaatta tctaagatac ataaaaatat
    41941 agttataaag atacctatga cagcagaagg tctaaaagcg gtgaaagtac tatcaagtaa
    42001 aggtataaag actaatgtaa cgcttatatt ctctgctgga caagctcttt tagctgctag
    42061 agctggagct acatatgtaa gtccttttgt tggtagattg gatgatatat cacaaaatgg
    42121 tcttgattta attgaagaaa tcgttgatat atttagtgta aatagtattg aggctcaaat
    42181 aatagttgct agtgttagaa atccaataca tgttttacaa gctgctagaa tgggagcaga
    42241 tatagcaaca gttcctctta aagttataaa ccaaatgatt aagcatcctt tgacagacaa
    42301 aggaatagat agctttatga aggattggga aggtgcttct ttaaaattat aattataaac
    42361 tacgctttat aattatatta aagaggttat tatggaaatt ctaagtaata aggctaggct
    42421 attttgccta gtcttatttt ggtgtataat atattgaaac atattattga aatagattaa
    42481 ttttttaagt gaggaggcga aaaatggata aaatattaag agagatacaa agagaagata
    42541 aaaaaaatcc atatactgac caagaacttg ctgaaatgtt aaatgtagct aggtctgaag
    42601 tgatatcagt taggaaaaaa aataatattt tagattcgag agaaagaaga aaaaaaatat
    42661 taataaaaga tatatcaaaa attgtaagtg aaaatcctca aatgtctgaa agaaaaataa
    42721 ctgaaatatt aatagaaaat ggatataata tatcgagaag tgcagtttca aaattattaa
    42781 aagaggaaaa tttaaatcag tcaaagattg ggattaagga taaagaccca gcatcatcag
    42841 gaaagtatgt gaaggtgagt aaagttgtag aagaagatgg atttgaagaa ttgataggta
    42901 taaagggaag tttgaaagaa aaggtaaatc tagctaagtc agcaataatg tatcctccta
    42961 atggccttca tactataata tatggagaaa caggagtagg taaaagtgaa ttagctacat
    43021 gtatgtataa atatgctata aaaaacaaca ttaaagaaga gaacagccca tttatagtgt
    43081 ttaactgtgc agactatgca gaaaatccta atctattgat agctcaactc tttggggtag
    43141 taaaaggtgc atatacagga gcagatgcaa atagagaagg tcttgtagaa caagctaata
    43201 atggaatatt gtttttagat gaaattcata gattgcctgc tgctgggcaa gaaatcttat
    43261 tttcattaat agatagagga gaatttagaa ggttaggaga aagtagttct aatagaaagg
    43321 caaatgttct cataataagt gctacaacag aaaatccaga ttctaattta cttcaaacat
    43381 ttagaagacg tataccaatg gtaataaatt tacctaatat gagtgaaaga ccaaaatctg
    43441 aaagatatga aataataata aagttttttg aaagagaagc aaagcgagta aacaagaatt
    43501 ttataataac taaagaagtt atgtgtgcac ttatgaatta taagtgtact ggaaatatag
    43561 gtcagttaaa gagtgatata caagtaactt gtgctagagc ttttagtaaa tcgatatttt
    43621 ctagcgataa ggtaattata gatttagata gtttaaggga ttatataaaa agtggatatt
    43681 atgattgtaa ttgtaaaaat gaaaagtatt ctgagttttc agttgaggat atatatatag
    43741 atattagtga attggtgagt ggaaaaaata gaattttatc tgataatgag ataagcgaga
    43801 tatataatta tgcagaaaaa gagcttaagg ttttggaaag taagtgcttt tcagaagaag
    43861 agttaaaaaa tgcatttata gaaaagttag ataagaagtt taatgctatt aaaaacaata
    43921 aaaatttatc tgatagaaga agtcgaatag actggggagg acaattaaaa gagtctacac
    43981 tggagataat ggataaggta attgtattta ttaaggagca gtttaagcat gtaaatcaag
    44041 gtctgtactt ggctctagca attcatattg agcatgctat aggtaggata aaagatggaa
    44101 aaactataat aaatccgagt ttagataaaa taaaagcatc aatgccaatg gaatatgagt
    44161 tgtcaagata tataatgggt atagtagaag atttgacaca agtaacattt ccagaagatg
    44221 agcttggata tttggcttat tatataaata aattttgtta taatgaggaa agtataaaag
    44281 ataaagttaa agtagtaata gttacgcatg gtaaagttgg aattgaaatg tctaaagttg
    44341 taaatcatat tttaggtata gaatgtacac taggtataga aatagcactt acagattcac
    44401 catcagaggg gatagagcat gtattagaag aacttcaaaa gatagaagct agaaaaggta
    44461 ttctagttct aattgatatg ggttctttgg taattcttgg tgatgaggtt gaaaaaaggc
    44521 ttggaattag atgtaaaact gtaaatagag tagatacatt attggcaatg gaagcaggaa
    44581 aacttgcaac cattgaaggg aaaagtttag atggtataat agctgattta aagaaaaata
    44641 agaattatgc tatgataaat acaaataaat ttagttacag aaaaaacgag tatggaaaga
    44701 aaaatgtaat cattacttta tgtttgagtg gtgtaggtac agctttaaat ttaaaagagc
    44761 atatagaaaa acaaattaag gaatatgaca ctttaattga agtaaagcca gttgcttttt
    44821 taaataataa tttagaagaa gagttaaatg atattgaatc tgaatataat attattgcta
    44881 tctgtggaac tattgatata gattataaaa acgtgccttt tatttcttat aatgaggtac
    44941 ttggtaaaaa tggtattaat aaagtattag agcatttaaa tagtaaacaa ccagctttaa
    45001 atattgaaaa ccagttgaat aatttaatac atgaagattt gattttatac aattttgaag
    45061 gaatttcaaa ggagtatata attgatactc ttgtttcaaa acttgaagaa ggtggatatg
    45121 ttgactcaaa gtatatatta agtgtatata aaagagaagc aatgggaagt gttgtaatgg
    45181 cctctaaggt agccgtgcca catggacttc cagaaaacgt tataaagcct gcaatagcaa
    45241 tcgcgaggtt gaataaacct atagtatggg acaataaatt tatggtggat ttggtggtac
    45301 tactggcact taaagaaaat aataagaaag aaatacgaag cttattttca aagattaatg
    45361 accagcatac tttagaagtt ttattaaata ctgaagataa aaatgaaata aaagaacttt
    45421 taagctaatt attagtaccg agaagaaaga caaaaaaatt tgctttagta taaaatttaa
    45481 aactactcaa
//
LOCUS       DAEOTL010000026        45431 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEOTL010000026 DAEOTL010000000
VERSION     DAEOTL010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45431
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.026"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            326..1162
                     /locus_tag="KRH82_001729"
     CDS             326..1162
                     /locus_tag="KRH82_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8655010.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1515..3092
                     /locus_tag="KRH82_001730"
     CDS             1515..3092
                     /locus_tag="KRH82_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8655011.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRIAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3085..4269
                     /locus_tag="KRH82_001731"
     CDS             3085..4269
                     /locus_tag="KRH82_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8655012.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPIGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4287..4886
                     /locus_tag="KRH82_001732"
     CDS             4287..4886
                     /locus_tag="KRH82_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBG8655013.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4910..5380
                     /locus_tag="KRH82_001733"
     CDS             4910..5380
                     /locus_tag="KRH82_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8655014.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5739..6485
                     /locus_tag="KRH82_001734"
     CDS             5739..6485
                     /locus_tag="KRH82_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBG8655015.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHMELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6546..7220
                     /locus_tag="KRH82_001735"
     CDS             6546..7220
                     /locus_tag="KRH82_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBG8655016.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTHGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLGHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLRCMMSCPWSL
                     RYANQK"
     gene            7588..8934
                     /locus_tag="KRH82_001736"
     CDS             7588..8934
                     /locus_tag="KRH82_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBG8655017.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQDIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGDNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIIALTGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMCYSQITARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLDEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGVNTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEQIDVKVLAGESMYYYKKIKD"
     gene            8961..10361
                     /locus_tag="KRH82_001737"
     CDS             8961..10361
                     /locus_tag="KRH82_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBG8655018.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSFKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKNICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAVICEDKQ
                     GEPGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNEDNWEDFKEDKH
                     KVYLIEALKTKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSNINGIGIS
                     DEDYGDKVKIKKGNIYINSNDKDIKMHKPEVGDIMSTIIKDKSILSAHYGGTWEKIGE
                     KIEFGITVHYYKLIEK"
     gene            10571..12007
                     /locus_tag="KRH82_001738"
     CDS             10571..12007
                     /locus_tag="KRH82_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBG8655019.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNKEPPAKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKNMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGKETVYYYKHHEPEKTNQIQ"
     gene            12351..13295
                     /locus_tag="KRH82_001739"
     CDS             12351..13295
                     /locus_tag="KRH82_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBG8655020.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLRDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDNNKQISIFD"
     gene            13464..14396
                     /locus_tag="KRH82_001740"
     CDS             13464..14396
                     /locus_tag="KRH82_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBG8655021.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGNFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14501..14968
                     /locus_tag="KRH82_001741"
     CDS             14501..14968
                     /locus_tag="KRH82_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBG8655022.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15212..16066)
                     /locus_tag="KRH82_001742"
     CDS             complement(15212..16066)
                     /locus_tag="KRH82_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBG8655023.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            16232..18196
                     /locus_tag="KRH82_001743"
     CDS             16232..18196
                     /locus_tag="KRH82_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8655024.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKFLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYTGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAINHITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18196..18657
                     /locus_tag="KRH82_001744"
     CDS             18196..18657
                     /locus_tag="KRH82_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655025.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18660..18980
                     /locus_tag="KRH82_001745"
     CDS             18660..18980
                     /locus_tag="KRH82_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBG8655026.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            18996..20096
                     /locus_tag="KRH82_001746"
     CDS             18996..20096
                     /locus_tag="KRH82_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBG8655027.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20216..22816
                     /locus_tag="KRH82_001747"
     CDS             20216..22816
                     /locus_tag="KRH82_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBG8655028.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
     gene            23285..23620
                     /locus_tag="KRH82_001748"
     CDS             23285..23620
                     /locus_tag="KRH82_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655029.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            23757..25034
                     /locus_tag="KRH82_001749"
     CDS             23757..25034
                     /locus_tag="KRH82_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBG8655030.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIRSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            25155..26543
                     /locus_tag="KRH82_001750"
     CDS             25155..26543
                     /locus_tag="KRH82_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBG8655031.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRTLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            26914..27627
                     /locus_tag="KRH82_001751"
     CDS             26914..27627
                     /locus_tag="KRH82_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBG8655032.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            27745..28614
                     /locus_tag="KRH82_001752"
     CDS             27745..28614
                     /locus_tag="KRH82_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBG8655033.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(28769..29914)
                     /locus_tag="KRH82_001753"
     CDS             complement(28769..29914)
                     /locus_tag="KRH82_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBG8655034.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDVDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(30248..31024)
                     /locus_tag="KRH82_001754"
     CDS             complement(30248..31024)
                     /locus_tag="KRH82_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBG8655035.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            31606..32580
                     /locus_tag="KRH82_001755"
     CDS             31606..32580
                     /locus_tag="KRH82_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBG8655036.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            32678..32983
                     /locus_tag="KRH82_001756"
     CDS             32678..32983
                     /locus_tag="KRH82_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBG8655037.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            33139..34299
                     /locus_tag="KRH82_001757"
     CDS             33139..34299
                     /locus_tag="KRH82_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBG8655038.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            34349..35251
                     /locus_tag="KRH82_001758"
     CDS             34349..35251
                     /locus_tag="KRH82_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBG8655039.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            35331..36224
                     /locus_tag="KRH82_001759"
     CDS             35331..36224
                     /locus_tag="KRH82_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBG8655040.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      36277..36458
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            36686..37816
                     /locus_tag="KRH82_001760"
     CDS             36686..37816
                     /locus_tag="KRH82_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655041.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            37888..38913
                     /locus_tag="KRH82_001761"
     CDS             37888..38913
                     /locus_tag="KRH82_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBG8655042.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            38916..40112
                     /locus_tag="KRH82_001762"
     CDS             38916..40112
                     /locus_tag="KRH82_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655043.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(40240..40965)
                     /locus_tag="KRH82_001763"
     CDS             complement(40240..40965)
                     /locus_tag="KRH82_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBG8655044.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            41443..43542
                     /gene="nrdE"
                     /locus_tag="KRH82_001764"
     CDS             41443..43542
                     /gene="nrdE"
                     /locus_tag="KRH82_001764"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBG8655045.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEAFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            43555..44526
                     /gene="nrdF"
                     /locus_tag="KRH82_001765"
     CDS             43555..44526
                     /gene="nrdF"
                     /locus_tag="KRH82_001765"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBG8655046.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            44602..45228
                     /locus_tag="KRH82_001766"
     CDS             44602..45228
                     /locus_tag="KRH82_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBG8655047.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT        17749 a         4819 c         7966 g        14897 t
ORIGIN      
        1 tataatctta atttcaataa atatatatat aattaagttg aaatacttga aaatactgga
       61 aaaaattgaa aataattttt gtaatataaa atgtcgattg attttaaata attaaatata
      121 cataagaaat aattaaatat ctttcaatga aaatatgata aaatatgaca aattaattga
      181 tgacaataaa aaatattttg ttattgtagt attatagggt aaattgcaaa atatatacga
      241 aagtaaaatt ttaaatattg acattaaatt aaatatacta tactatgtaa gtgtgatgag
      301 agaatttttt tagaggggat ttatagtgaa tataaaaaag atatttaata acaatgtagt
      361 agtaagctcc ctagaagatg gcacagaaat aattgtcact ggtgctggag taggatttaa
      421 gaaaaaagta ggcgatttga tagatgaaaa tttgatttct aagaaatatt ttgttcaaga
      481 cgatcaaagg gacaaataca atcaaatact taataagacc tctattgaat actttaaaat
      541 ttcagaagaa attatagaaa aggctaatga agttttaaat actcaagtga atgattcaat
      601 aatattagcc ttaactagtc acatagaatt tgctgtccaa agagaaaaac aaggtataaa
      661 attaccaaac ttaatattga atgagacaaa acaactttat agggaagaat ttgaatttgg
      721 attatgggca attgatgaaa ttgaaaaaag gataggaata aaattgcctg aagatgaagc
      781 aggatatatt gctattcaca taatcaatgg tttggaaaat tctcaaaaag atgaaggtat
      841 taatatacta gagttttcaa aacaagttat tcagataatt gaagaagtac atggatttaa
      901 attggatgta aattcattaa attatactag acttataact cacttaaagt tttttgttca
      961 aaggattctc cgaaaagaaa cttacaatga tagtgatatt gaagatatgt ataagttagt
     1021 gaataaaaat tacaataaac ctaaagtgtg tactgaagaa attgcagcat tggtattaga
     1081 cagatttgaa tataagatta gtaaagaaga agaattatat ttaatgattc acataaataa
     1141 aataacaaac agtggttgtt aggattgtaa ctgataaagc aggcaaaacc taagtcattg
     1201 agcttaacta ttagattaag ttttttgatt taggtttttt tattagatac aatcaaaata
     1261 cagacagtga cttttaggat tgtaactggt taagcaggca aaacctaaat cattgaattt
     1321 aactattagg ttaagttttt tgatttaggt ttttttatta gatacaatca aatacagaca
     1381 gtgactttta ggattgtaac tggttgagca ggcaaaacct aaatcattaa acttaattat
     1441 taaattaagt tttttgattt aggtttttct ataaatttga ttatgttttt agataaaaat
     1501 aggaggggaa aattatgaaa aaaaataagt taggtttatg gaacttcttc caaatgttag
     1561 gaaaaacgtt tatgttccca atagcactac ttagtgtttc tgggatgatg ctaggacttg
     1621 gggcaggttt tacagaccct aagatgattg aaatggttcc atttttaggg aatgaatatg
     1681 ttaacttagt tttaaacttc atgttaacaa taggattatt tgcatttaac aacttgggag
     1741 cattatttgc aatggcaatt ccactaggat tattaaaaaa agaaaaagag tttggtgctt
     1801 tttcaggatt agtaggattt atagcaatgc atataggtac aaatttttat ttaacaagag
     1861 ctgatttgtt agtaccagca gaacagatgt caactaatgg tcaagctatg attatgggta
     1921 tacaaacata taatacaagt gttttaggtg gtattgtagc aggattaatt gtttatgcaa
     1981 tatatgataa agttagtaat ttaaagatac cagaatcatt aggattctac agtggaccaa
     2041 gattagttcc aattgttagt ttaatagtta tgagtatagt tggattatta atacctattg
     2101 tttggccacc atttttcaat gcattccaaa gtttaggaag atggatttct tcagcaggac
     2161 cattaggata tttttcatat gcagtggcag aaagagttac aattccattt ggactaaatc
     2221 atcttgtaac atccgtattc cgttttacac caataggtgg aactgctgtt attgatggag
     2281 aaacgtactt tggtacattg aacatgttta tggcatatgt agaaaataat cagattatac
     2341 ctcttgattt agctggtaaa atggaacaag gtaaattgat gattcaatat ggattagctg
     2401 gtgctgcatt ggctatctac cgtatagcaa aaccagaaaa tagaaaggca cttaaaggac
     2461 ttttaatatc aggggtgttg acagttatta taggtggtat aagtgaacca atagagtttc
     2521 tattcttatt catatcacca gcattatttg ctttccatac atttatgaat ggtctagcaa
     2581 acatggtact tccatactta ggcgtgttga tgggattcac aggagattta attgcattta
     2641 taagttttgg tgtgttaaga ggaacagcta caggatggcc aatagcagta ttagtagcag
     2701 ttttatattt tgcaatatac tattttgtat ttaagtgggc aattattaag tttaatataa
     2761 agaccccagg acgtgaggat aaagaaataa aagtatctga aggaaatggt tcagatttca
     2821 aaaatttgtc tacatataaa ggacaacaaa tgatatctgc tttaggtggt caatctaata
     2881 tattatcact agataattgt gtaactagat tgcgtttaaa actacaagat gtatcattaa
     2941 taaatgagga tgcaattaaa gaggctggtg gtatagcagt tgttaaattg gatgagcata
     3001 caatacaagt aattatagga actcaagtgt attctttaag aaagcagatg gataaagcta
     3061 tggaaggtca tttggaggca tgtaatgatt aattttgata aaaaagtaga ccgattgggt
     3121 acatattgta cccagtggga ctatgtagaa gatagatttg gtaagaagga tttgcttcct
     3181 tttacaattt cagatatgga tttagagttt ccatttgaaa taacagaggt gttgcaggaa
     3241 aggttaaatc atagagtttt gggatacagt agatggaaac atgatgattt tagaaattca
     3301 gttacgaatt ggtatattaa aagatttaat tgtagcgttg atagtaactg gatatattat
     3361 agtccaagtg taatgtattc aattagcaaa cttattgaga tgttaagtaa tgaaggagat
     3421 ggaatcctta taaatactcc tgcatacaat gctttttatg atgtgataac aaataacaat
     3481 cgtaatatta taaagtcaca tcttgtaaat aggaatggat tctattcaat tgattttaat
     3541 gattttgaga aaaagtgtaa aaaatctaag atatttattt tatgtaatcc tcacaatcca
     3601 attggtagag tatggagtga gttagaactt gttaagatga taggaatttg taagaataat
     3661 gatgtcaaga taatatcaga tgatatacac atggatattg tatatgacaa tagaatgaca
     3721 cctatcttaa atgttgcaaa ggactattta gattctgtat tcatttgtac atcagcgtct
     3781 aaatctttca atataccagc attgactggg tcatatgtga ttataccaaa tgaaggtatt
     3841 agaaataaat ttgaaaatat cactagatac cgtgattttg taaattcgcc agcaattcta
     3901 gcaatattag ctacaatggt ctgttatgat gactgcgaat attggttaga tgaactatta
     3961 aaatacctta aagagaatct taaatatacg attgattata taaaagataa tttagaacca
     4021 ttgaaattgg tcatgccaga aggctgttac tttgcttgga tagatttttc cgaacttaaa
     4081 ataagtggtg agaaattcca aaaattattg atggatattg gagaagttgc tattatgtcg
     4141 gggtctgtat atggtgaaga aggtgagttt tatttaaggt taaatgtggc atgttcaaga
     4201 gaaaaacttg aagatggttt aaataggatt aaaaaaacta tggattatat tgcaaaaaga
     4261 attttatagt aggaagggag atagttatgg gatatttaaa aacaatggtt gatgttatga
     4321 ctactgaaat gaatgccata agatgtttaa tagatgaagc aggaatagaa tatgaaagta
     4381 tagttagtga aattgcaaat tgtgaaggca aagtaatttt tatgggtgta ggaaaatctg
     4441 cacatatagg taagaaattg gcagctacat ttgctagtac tggtacacct agcttttttg
     4501 tacatgcaac agaggcagtg catggagatt taggaatgat tgaaagtaag gatattacaa
     4561 ttttaatatc aaatagtgga aattctatgg aagtggtaaa ctgtataaaa tatattaaag
     4621 caataggttc taagacaatt gcatttactt caaacagaaa ttcagtactg gcaaaagagt
     4681 gtgattatgc tttaatatat cctgcaaagg atgaagcaga ccatttaaat ctagcaccaa
     4741 caacatcatc tacaattact ttggttttag gagattctat tgcatgtgca ttatctaaga
     4801 gtagtaattt tggttcttca gatttttata agtaccatcc aggaggaagt ttaggtgaga
     4861 agttaaaaac agctaacaat ggataaaagc aaaaaggaga gtagttttta tgttcaaaat
     4921 gtttaaaaaa aaatcaataa aatcacccat atcaggaaaa gtaatagagt tatctaaaat
     4981 acaagatggt gtattttctc aaaaaattat gggagagggt gtagctatag attctacagg
     5041 agacattgta tatgctccaa tcaatggaaa gatagtagta gtagcagaga ctaaacatgc
     5101 atttgtaata gaattagaaa atgggatgga acttcttatt catgttggtt tagatactgt
     5161 aaatttaaaa ggcgaaggtt ttgaggtatt ggtgagtatg ggagaacaag tgaaggaagg
     5221 aacaccaatg ttgaaaatta accgtccttt gattgaatca aagggtatat cacttattac
     5281 tccagttaca ataactaatc attcagagta caatatgaat acatgtaatg taggcaatag
     5341 tgttgaaggt gggaaagata ctgtaattga gtttaaataa agaactaaaa tacaaggtta
     5401 atatttataa atacctataa acttatgttt tataagattg attgtataga tttgttgtat
     5461 aaaaaagaac tctttaatta taaattaagg agttcttttt tattttgtaa atattgttta
     5521 gatttatata gaaaaacact tagtaataaa tagaataaat aagtatttat atagctaaaa
     5581 atctaaatag ttttgtttaa atatattttt atattttgta atttcaaatt aataaataat
     5641 tagatttgat aaacaaaaaa taaaaatgtt gattacatta ataaacttta atataatata
     5701 tttatgaaaa atgtaaactg tgaaatggag gtagtaacat gaaaattgaa aatctttcta
     5761 ttgatgatat taaacgaggc tatatattta atgatgattt aaattgttat agttgcatta
     5821 aatgtacaaa aacatatgag gtaggagaaa tatataaaat aggtaataga ttctttgaag
     5881 cttcaaaagc tattgaactt catatggaat tagaacatag tgattattta gagcaattgc
     5941 ttaatagtga ttcaaagtac aacacattga ctgaaaatca aaaacaatta tttcaattat
     6001 ttattagtga tttaccagat aaggagatag caaaacaggt tggagtatcc acatctacta
     6061 tacgccatca aaaatttatt ttcagagaaa aagcaaaaca ggctaagttc tatttagcac
     6121 tatatgaatc tgtatttgaa gataaatcta ataaaagtag tactataata ccaatccatg
     6181 aacatgctcg aatggtagat gaaagatatg tagtaactga agaagagaga aaacacattt
     6241 tggatacatc atttgaaagt atgaatcctt taaaattaaa agtattttct tcaaaagaaa
     6301 agaaaaaggt cgtaatttta tctaagattt tggaacaatt tgaacgtggg aagaaatatt
     6361 cagaaaagga agttaatcag attttagaat ctatatatga tgattttgca acaattagaa
     6421 gatatctaat tgagtatggt tttatgagta gaaataaaga atgtacaaag tattggttaa
     6481 cataattaaa ataataaatt ttactaatgt gtaatgttat ttttatctag ggggaggagt
     6541 caaatatgaa tgatgaatta aaatctattt tatacaataa aggtgtagac attgttcgct
     6601 ttgttgatat atctgaattt ccaataaatc aaacgcacgg tttttctaaa gcaattttat
     6661 tttgtatagg gttatcaaaa aaatttatta cagatatata caataactta cctacagata
     6721 gtgatgagtt tttggaaaaa gaggagaaag tagaagaatt agctgactgg atttcaaaat
     6781 atattcaaaa taaaggatat agagcgtatt ctcaatcgga gaaaaacaat ctaggacatg
     6841 gatattttga aaaagcctat attaatccag aaatgcaatc agggattagt cctttaccac
     6901 ataagacaat agcaaatatt agtggcattg gatttatggg aaaaaataat ttgtttgtaa
     6961 cagaggaata tggatgtgct tttagcatgt gtacagtact tacagatgct ccaatttctg
     7021 ttgaaagata tcctttgatt gattcaaaat gtatggattg caatgtttgt gtagagaact
     7081 gtcctgcaaa agctatacat ggaaatgaat ggactttacc tggaaaaaga gaatctatta
     7141 ttgatgtttc aaagtgtttt tgcgtattga ggtgtatgat gagttgccca tggtcattaa
     7201 gatatgcaaa tcaaaaataa ttttactaga gaaggtatta aattgaatat tataaaattt
     7261 ttaaaatgta agattatata agatttttca aaataaaaat ttgtatagaa cactcagaaa
     7321 tgagtgtttt tttattggaa ttaaattata ttgatacaaa gcttaactat tttaatcatt
     7381 atataaactt tgtattaaaa aattaagaat aacttgctaa tagtaaaaat ataatgagat
     7441 tataattgat ttataatata actgtaatga tgttgtaaaa tgaaaattgt catctcaaaa
     7501 ttcccaaaaa gagtaaaagt cacttcggtt atagtcaaaa aattttttca gtgaaaataa
     7561 tttagattta aaagggagga attaatcatg gaaattgaaa ctaaaactcc agattggatt
     7621 aatgtactag aattaaacag taaaatagat attactggga aatatgatgt aagtaatatg
     7681 atacaagata ttgtctctga taagtcacta gaaggttcca ttatatattt tccaaaaggt
     7741 aattatttat ttgagaaagg tattaaaatt agtcaacaaa taacacttca aggagattct
     7801 tattatggag gagataatca agtatcaaat ttagataaaa aacaatcaat cataggaaca
     7861 accaatttta taactcgagg agtttctaat atgagtatta ttgcattgac aggaacaagt
     7921 caatgtatca aaaatattaa tttttattat gatagtcatg atatagagaa aataccgcct
     7981 aaaaatgtat ctgctattac agaatatgga gaaacacaag gactatctca ttttgaacac
     8041 ctgtttattt ctggattttc agggatagga attgaaattc catactattc aactggtaat
     8101 gatattactg ttagttcatg tggtcttggt atgaggcttg gagagaagtc aatgctttct
     8161 agtagcaaga tttacgaatg taaaaatgga atggagatta ctactggtgt tagcttaaat
     8221 aatgtgagaa tagaagaaat aaaagaaata ggtattaata ataaaggatt tggttttaac
     8281 ctgattatga atcttatggt agaccaatgt ggatattgtg gatttatgtt tgaaaaaatg
     8341 tgctatagcc agataactgc cagaattact agatgcggtc agtattataa aagtgttgat
     8401 tataatgctt atgagaatat ggaagatagg aaagaagaag cttattccat tttttatgga
     8461 gatattttag aaaattgcaa tattgtattg atgaatagta atattgatac cttggaaaat
     8521 gattcacttg atgaacataa gatatatgta atcaaggcaa atgaaacaaa caatgtaatg
     8581 ctaacatgtt atgctgaagc agataacttt atacaatgtg caaaaggtaa cttgctgtta
     8641 gaaaatggcg taaatactta taaattttat aatggtgaga tttgttctgt aggaggtgtt
     8701 caaatttctg atatagatga aaaagattta atcaaaataa tcgagaacac tctgtatata
     8761 gatgataaag gtaagtattt aatggttcct agattaaaaa agaatactgt aatatattca
     8821 gtactagatt ctacagaaga aataaataaa ttacatggtg gaatatggga acagattgat
     8881 gtaaaagtat tagctgggga atccatgtac tattataaaa agataaaaga ttaaattatc
     8941 aaactaggag gtagtgatta atggaagagt ctataataat taaagatata agtggctgga
     9001 ttaatgtact tgattatgga atttgtaatg atgaaacaaa agatgtaagt tttaagttgc
     9061 aagagattat ggatgctgta ccagaagatt ctattatata ttttccaaaa ggaaaatact
     9121 tatttgaaag tggtgtcaag attaagaaac gattaacctt atgtggagat tcttatattt
     9181 tagcgaatgt tcctaaaaat actgctggag taacacagtt tacttttaaa ggaaagaaaa
     9241 atcctaaaag tgaaaatata gcaatcataa cagcaaaaag tgtaagacac tgtattaaga
     9301 acatttgctt ttattcagat agttgtgata gagatatgac atctaatcat gaacctccaa
     9361 cagatggaaa acctagattt catcataatg taattataaa ttatagaaat atatctgctg
     9421 ttatatgtga agataaacag ggagaaccag gtcattatga aaatctatct tttagtggtt
     9481 tttctggaat tgcacttgat atgcctaata attctacagc aaatgatatt acaattttta
     9541 catccggact tggaattagt acaggggaaa attcaacaat tgctaacagt aaggtttggg
     9601 gctgtgttga tggaatgata atttctactg gaacttttat aaatggtatg agggtagaag
     9661 aaataaaaaa agttggaatt aaaaatattg gtagaggttt aaattttatt acaaatatca
     9721 caattgacca atgtggatat tgtggagttt ggtttgattc tatatccaat gttcagatat
     9781 caggaaatat cacaaggtgt gggcagtact attatgatgt aagctatgat aattatttaa
     9841 tgttggataa tagagttaaa gaagcatatt ctttattcta tggtaattta ttggaatcaa
     9901 gtaatatagt tttatcaaat accaatgaag acaattggga agatttcaaa gaggataagc
     9961 ataaggtgta tcttatagaa gcacttaaaa ccaagaatgt actattaaca tgtaatatag
    10021 atgctactga ctggattgtt aagtcagaaa aaggaaattt aacgtacaat aatatgcgac
    10081 aaactgttat attttacgat ggaaaactaa gtaatatcaa tggaattggt atatctgatg
    10141 aagattatgg ggataaagtc aagataaaaa aaggaaatat atatataaat agtaatgata
    10201 aggatattaa gatgcataaa ccagaggtag gtgacattat gtcaacaatt attaaagata
    10261 aaagtattct ttctgctcat tatgggggaa catgggagaa aattggtgaa aaaatagagt
    10321 ttggaataac tgtacactat tataaattga tagagaaata agtaaatacg tagtatttga
    10381 atagatgtat tttattggag ggctaggact atagttttaa tgtaaatggt ttggtaatag
    10441 catggattga ataatataaa aataatataa aaaattaatt tgattatgta aatttctatg
    10501 aagtagtaaa actgtgactt tagtcatagg aggttcaaac taagtaaaag ggaaaggaat
    10561 atataatatt atggaaggaa gaactgggat taaagatgga agatggatta atgtagtaga
    10621 aagaggtatt aaaaatgatg gttcgtacaa cgtaggtcct gctttgcagg atattattga
    10681 tgaaatagaa acagattttt gtgtcttata ttttccaaaa ggtaaatacc tatttacaag
    10741 tggtgttaaa attaataaag aaattgtatt gcaaggtgat tctaattcat ctacaggtac
    10801 tacacaattt ataactcgtg gagtagaaaa tatgagtatt attacattga cagggaagaa
    10861 acaatgtatt aaaaatataa atttctattc tgatagttgt gagatacaag taaataaaga
    10921 accaccggca aaaggtaatc ctaaatatca ttatgagatg attatcaata agaatgaaaa
    10981 gaatgttgag atgaataatg tatcagcaat cctgtatgat aacagtaaga atatgattaa
    11041 aggtctaggt cattatgaaa atatttatat aagtggtttt tcgggtacag gaattaggat
    11101 accatattac tcaattgtaa atgatattac agtttcatct tgtgggctgg gtattgatac
    11161 aggaatagac acaattattt ctaatagtag aatatctaag tgtcaaaatg gaatgaggat
    11221 taggactgga actagcataa ataatgtaag aattgaaaaa atacagaaag ttggtcttat
    11281 aagtagtcaa gttaaggggt atgaggggta tggaagttat aaaattaata atattacgat
    11341 tgaccaatgt gggtattgtg gcttttcatt tgattcaatg aaagatagtt atttttctgg
    11401 tattataaga aggtgtggtc agtattatta taatacagat tatgacacat atttaagtat
    11461 taaagataga gtagaagaag catattcttt attttatgga aattatttta cagaatgtaa
    11521 tattgattta gttagtgata ataaggataa ctgggatgat ggcttagaat ataaacataa
    11581 agtttatgta tttaaaaccc ttcaaatacc aaaattaaca ttgagatgca atatagatgc
    11641 ctatgattat atcgttaaat cggtacatgg aggaggtaat ttaatgttaa aaaataactt
    11701 taacaattat atatttattg attcatctag tccagaagtt attaatggaa ttaattttaa
    11761 ttatcaaaag aatggaaacc tgttaaggtt aaataatggt aaattaagtt ataaaaatgg
    11821 aaaggaagaa acagctatat tcagacctaa ttatggtctt attgtagcat caacagattc
    11881 agaatgtgaa caaatagagg ctacctatgg agaaaaatgg gagaagcttg gttctgaagt
    11941 aattggaaaa gaaacggtat attattataa acatcatgaa ccagaaaaaa caaaccaaat
    12001 acaataaaat ttgtattata taatgatata aagttttaat atatagtgtt tacctttaat
    12061 gtaatattga tatatttgta tagtattaaa tttgttaaaa agtaaaattg tagggtgctt
    12121 gaaaatagca ccttttttag tttcattata aaattagttt tgaaagttta ggaataatgt
    12181 atatttattt ttaaagaatt ataactttat taaggatatt ttaaatgcta gaaatgaatc
    12241 agtaaatcat actggaatta tcttaaatgt tttgattaaa ttaagtattt agagctataa
    12301 ttatattaaa aatatattag aacataatta tattactatg gaggttaaat atgatagtaa
    12361 gtgtgagtag aagaactgat atacctgctt tctatagtaa gtggtttttt aacagacttg
    12421 aagaaggttt tgtttatgta attaatccaa tgaatccaaa acaggttagt aagatagagt
    12481 taaatccaca tactgttgat tgttttgtat tttggacaaa ggatgtaact ccaatgttat
    12541 atgatttaaa taaattaaga gactataaat attattttca ctatactata acatcatatg
    12601 gaaaagaagt agagacatgt attttagata aaagaaaggt aatagattca tttaaggaat
    12661 tgtctagaaa aataggcaaa gaaagagtaa ttttaagata cgacccgatt ttcttaagtg
    12721 aaaagtacac agtagattat catatcaaag catttgcgag tttatgtaat cagcttgatg
    12781 gatttacaga aaaatgtata ataagtttta tcgatttgta taagaaaaca aaatttaata
    12841 ctaaagcatt acatataaag ccaatagaaa ttacagaaat agaaacatta tcaaaagaga
    12901 tttctaagat tgctcataag catgggataa tacttgaaat gtgttctgaa gaatataatt
    12961 taagtaaatt tgggattgga aaaagtaagt gtattgatga tagattaata tcaaaaatta
    13021 taggatgtga agtagaggta aaaaaagata gtacacaaag agatatttgt ggatgtgtta
    13081 aaagtgtcga tataggacaa tacaatactt gcagacatta ttgtctgtat tgttatgcta
    13141 actttaatta tgcaaaagta gaagaaaact gtaggcttta taaggaagat aataaattac
    13201 tcatagatac tttaagagat gatgcaaaaa taagcattag agatatgaag actattaaag
    13261 tagataataa taaacaaatt agtatatttg attaaaataa atatactaat taccttaata
    13321 tattaagaat atagatactt ttgataataa aattaaactt aatagatatt ttctatataa
    13381 gaaagatggt cataatatgt caatttgacc atctttttga tataattaaa acacaaataa
    13441 tttagtaaca aaggaggcag aacttgaatt tattaaaaaa atatcctata cctattgcaa
    13501 gtttgatttt atcaattttt actttaggta acttattaca atcttatagt gaatcattac
    13561 gtaatgtaat tggatttata ggatttattt tgtatgcaat ttatatagtc aaaataatat
    13621 tacttagaaa gggtgttaaa gagcaattag agaacccttt aatatcaagt acatttccaa
    13681 ctataacaat ggcaacaatg atatttgcta catatataaa accattatct ttagaattaa
    13741 gtattatgat ttggagcata ggaattgtgg gtcatcttgt gttaatagtc ttatttagta
    13801 agaagttctt agttaaattc tcaataaaaa cggtatttcc atcttggtat atagtatatg
    13861 ttgggatagt tgcagctagt gttacggcac cagcatttaa tcaacttttg attggcaaaa
    13921 ttgctttttg gataggattt gtatcttata tagttcttat accagtaatt ttaaagagag
    13981 tatggataat caaggaaatg cctgaaccat ctttaccaag tatagctata ttagctgcac
    14041 cagggtcact attattgtct ggatatatta attctttttc agataaaaat aatgtagtat
    14101 tatacttgtt attcatatta tcaattgtat tttatattat agttttggga tatttaccaa
    14161 aattattaag attgcctttt tatccgagtt ttgctgcatt tacattccct atggcaataa
    14221 gtgcaatggg tatgaaacta atgaatggtt atttaactaa atcaggtaat tttataagtt
    14281 ggatttcata tgcttctaag ttagaagaga taattgctac agtgattatt ttatatgttt
    14341 tagttttgtt tattatatat cttagtaaat ctgaaactac atctaaagct aaataagaat
    14401 tattaaatat gtgtatttaa taggaatatt gatataaata tatgaagata agataaacca
    14461 tagaaactta atttagctta attttattgg aggaaaacaa atgaaaacaa aagaagaata
    14521 tttaaaagaa gttagaaaca tatcagaaga atactttaga aaaggagagt ttttttgctc
    14581 tgaagcagtt ctccagacaa taaatgatgc tttaggccaa cctttaagtc cagagataac
    14641 taagttagca tcaggatttc cgataggact tggaaaggca caatgtcttt gtggagcaat
    14701 atctggggga gagatggctt taggtatagt atatggaaga gttcatggtg aagctatgaa
    14761 tccaaagatg tttgagcatg ctaaaggttt gcatgattat attaaaaaag agtatggtgc
    14821 aacatgttgt agagctatta caaagaaatg ggatggtgat aactttatgt ctcctgaaag
    14881 aaaagagcac tgtattaaaa taacaggtca agttacagag tgggttgcag ataagcttat
    14941 agaagatgaa aaacttaata tcaaatagtg taatattagt tggtgaattt ataaagttaa
    15001 atttacttat agtataagat acttgatatt ctcgtattga tagaaaaatt tatagcatat
    15061 gtatttaatg aaatatactt atatttagag tgtggtttaa tttcataaat acatatgcta
    15121 ttattttaag tatataagca aatttattta aataaataga aacagttaat ttatatgtac
    15181 aaaactatat atgattagtg taaataaata cctattttat aatactcaac ataaagacac
    15241 cagacatgat tagtattata ccaataaaaa tagcaagcca ttcttttttg ttcttctttt
    15301 ctttaaaaaa tataatccct cctaaagtgg ctactatcac acaactctga gagatagaaa
    15361 aacttattgt aactcccaat gtattagtcg ttatgaacat acctaaattt gctattgacc
    15421 acaatatacc agtaattaaa ttgaataaaa cattttccct atatacaatc tctttagaaa
    15481 aatacttgac aataatagat gaagttatca acataccaac agattgaggt aatataattc
    15541 tgtatccttc aattaaaaat atttgattag ttacaacata taatgataaa aatagagatg
    15601 ataataatac aactccaaca cattttaaca tatttttatc tgtagatttt ttagtttgat
    15661 aatttgtgag aagtatacca agtattatac ataatattga taaagaacca atcagtaaca
    15721 ttttagaact ggtccattcg ttaaacaaga ttacagctaa taatgtcgta aaagttaatt
    15781 gtgaaccatt tgaaattggc attactttag atacactagc aatttgaatt gctttaaact
    15841 gcattaattg tcccaaactc cagaatatgc cagaaatcat acttatacaa aatgaaaaaa
    15901 atgtaatttc aggatgtata accagagtta ttatagtgga aaatataaac gcacttatgg
    15961 atgtacctaa aagctgttca tgaggagaac ttttctttag atttgcaact atgggcatca
    16021 atccccatcc cattacagga agtaaagcaa taattattgt cagcattaaa ctatttcctt
    16081 tcatattaaa tttagacagc ttttaattta tcatctaaaa ttaaagtgtt caatacataa
    16141 aaattaccgt atttaatcag gaaatattag tagtttttta gaaaaacatt ttccattaaa
    16201 ataaagacaa agggaaggag taaaattgaa aatgttaact gatatgattc aaaatcgtga
    16261 aattaaaata ataaagtttt tattaaaaga aggtcataca actgtaaaag caatagcaga
    16321 tgatttagat gtttcagaaa aaacagtttc aaaatttctt aaagaagtag aagcagtgct
    16381 taaaaagata ggtctttctt taataagaaa acctaagata ggtgtttata ttgatggaga
    16441 tttaaaaaaa atacttcctt acctagataa taaaggaagt caaattccta caaccagaga
    16501 ggagagagtt atctatatat attcagtact tttaaagagt aatgattata ttactataca
    16561 acaactttct gatgaactat atataagtcg tggaactatt gaaagggatt tagcagaagt
    16621 tgaaaaactg ctaaaaaacg aagggatttc catatataag aaacctagta agggaataaa
    16681 gttaaatata agtgaaagag ataaaagaca acttactgct aaatttatac ataaattttg
    16741 gagtagaaac tggtatatta agcaagagca agaaagcttt tatcaagcat ttgaaaagat
    16801 acaagcagat gtaaatggta ttttttcgga agatgattta tcaataatta ttgatattct
    16861 taggaatttc agcagagaaa gaaaatttga gttctctgat tatgaatttc agtcattagt
    16921 tattcatttg gcaatagctg tagagagaat tagaaaaggc gaatatatag aagaaagttt
    16981 gtatactggt aatatagaaa ataatcaaat gtcaaatacc aattatttag caaaacaatt
    17041 agaagaaaaa ttttcaatat tattaccaaa atctgaaatt ggatatataa atttacattt
    17101 agtagcgtct gaccaacata gagatactaa tgaactaaaa aatacttcaa ctaatccttg
    17161 tgagacaagt acaaataata tatcaaatct tcgggaaatt ataaaaaata cattgtatga
    17221 gacagcttat gacaaggatt taattgatgg attaacttca catgtacatt catcaataaa
    17281 tagactgaaa tatggactta gtattaaaaa tccatatgta aatacaatca aacaaaactt
    17341 ttctttatca tttgagcaag ctttagattt aaagaaagta attgaattta tatatgatat
    17401 taggataaat gatgatgaat gtgcttatat agcattacat tttgaagctt ttagagaaag
    17461 aatgaaagaa cttccacaaa atattagagt aattctagta tgcagtacag gattaggttc
    17521 atctaggtta ttgtctgcaa gaataaaaaa atactttcca atgataaaga ttgaaaaagt
    17581 actttccgta caagaattag tatccagtaa aattgatgca gatttagtaa taagtactat
    17641 ttatttagag ttagaaacaa ttccaaccat agtagttagt cctattttaa atgaaagtga
    17701 tataagaacc ttggaaagaa atatacaaaa tgtttcaagt tgtacttcta agaagtataa
    17761 atctttcaga aatttaatct ttgaagaaaa tatattgttg aatattgaag cttcaaatta
    17821 tgaagatgca attaatcata taacagataa cctaataaaa aaaggttttg caaaagaagg
    17881 tatagctaaa agtgcaattg agagagaaaa tttatcttac acttctttcc aatcaatagc
    17941 tacacctcat gctaatccta gttatattaa aaaatctaat atatctgttg caacgttaaa
    18001 aaatcctatt acatggggaa atgaaaaggt ggaagttatt ttctttattt cattagaaaa
    18061 tgacaaaaac ctagagcttg atgaaatata tgaagttttt tatgacttta ttgacaataa
    18121 aaaaaatata aatgacatat taagtgcaac ttccacaaag gaagtgtacg atttgctagt
    18181 ggaggagagt atatagtgaa aatatcagat gtattgaaaa aagagcaaat tgtttttaat
    18241 cttgatacaa atacaaagga agaaacaata aaaaaattaa gtagtatatt tgttgaaaat
    18301 gggattgtgg acaatgaaga agaatatgtt aagtctgttt tggaaagaga agaacattca
    18361 actacaggta ttggtaatgg tattgctatt cctcatggaa aaagtaatgc tgtcaaaaaa
    18421 tcttctataa tatttgcaaa gactaagcat aagattgaat gggatgcttt agatgaaaaa
    18481 ccagtagata gtattttctt attggctata agcaatattg ataaggatag caatcatctt
    18541 gtactattat ctaaattagc aactaaactt atggatgatg acaatgtaga tgcactaaaa
    18601 ttagccaatt cagaacaaga aataatcaat atatttagtg aagaaggaga gatgtagaaa
    18661 tgaaaagaaa aattatagca gttacagcat gtgcaacagg agttgcacat acatatatgg
    18721 cagctcaagc gttaaagaaa gcttcaaaaa agatgggtca ccttataaaa gttgaaacac
    18781 aaggagctac aggaatcgat aatgagttaa ctacaaagga tgcacaaatt gcagaagtag
    18841 taatatttgc agtagatact aaagtcagaa atgctgaacg ttttgaggga aaagaaatac
    18901 tagaagtacc agttaatgca cctataaagg atgcagagaa agtaataaat gatgcactaa
    18961 agttaattga cactaaataa atggagggaa atataatgtt gaaaaagata gtctctgagt
    19021 taaaaaagca tgtcttaact ggaatctcat atatgattcc attagtaatt gcaggtgcta
    19081 tgataatggc gatatctcgt gtaggtggtt ctttctataa tataccagat atatgggatg
    19141 ctaaatatgc agaaagtgct agtagtattg ttagattatt acatgattta gatgggtttg
    19201 gaggtactgc attaggatta atgtttcctg taattgctgc atttatagga ttttctatag
    19261 ctgataaatt agctattgta ccaggtcttg ttggaggtat gattgctaaa gatataggtg
    19321 caggattttt aggagctttg gcagttggtc ttatagcagg atatacatgt ttgtttatta
    19381 aaaatcatgt taaattacca aaatcagcag cttcaatagt accaatattt atagtaccag
    19441 tatttgggac attaatcact gttgtattaa tcaattatgt gataggtata ccttttgcca
    19501 cattaaatac tggattagaa aattggttaa atggattatc tggtacaaat cagatattaa
    19561 tggcagctat tataggggct atgatggcag ttgacttagg tggaccagtt aataaagcag
    19621 ctttaacaac atcacttgca ttattaacaa gtggaattta tgcgcctaac actgctgcaa
    19681 tggtaggaat agttatacca ccactaggat tgggacttgc tactatacta gcaaaacaaa
    19741 aatataataa acagttacgt gaagctggaa aatcatctct tataatgggt ttaattggag
    19801 taagtgaagg agcaattcct tttgcagtag aatctccatt aaaagtaata ccttcatgtg
    19861 taattggaac agcaattgct tcagctatgg cagttggttt aggttcagta aatgcaactc
    19921 caattagtgg attttatgga tggtttacag tagagaattg gccaatgtat gtgttatcaa
    19981 tagcagttgg aacagtaatt gtagctggat tagttatagt attgcgtgga aatccagtga
    20041 ttgaggatga tgaatttgaa gatgatgatt ttgatgaagc agagtgggaa tcttaaaatt
    20101 taataactat ttaagacgtg ttataagcta tattcaatat gaatcttata ctaaataaag
    20161 tgttaaacat tcagtttaga cttaaatata aaagataaag aacagaggag aataaatgat
    20221 aaaagcacat attgttaatc atacacactg ggatagagaa tggtatttta cttctggaga
    20281 tgcattagta cttagtgaac aactatttac agatgtaatt gatgaattag aacgtaatcc
    20341 agatgtaagt tttgtacttg atggacaact ttctattttg gatgattatg tacaattaca
    20401 caaagaaaaa atagaaatca ttaaaaagtt aataaaagaa gatagactac atattggacc
    20461 atggtttact caaactgatg cattctttgc tagaggagag tctattttaa gaaacttaat
    20521 gattggaatt tttgaaagta aaaagtatgg taagtatatg aaaattgggt atttgccaga
    20581 tacatttgga tttaatgcac agatgcctat actattaaag catgtaggtc ttgataatat
    20641 attcttttgg agaggtatac atcttggtaa acaggttcaa tcaccatatt ttaagtggaa
    20701 aagcttaaat ggagaaagtt atatatatgc agtaaatatg ccacatggat atggaactgg
    20761 tatgctttta gagccttcat taaagtatgt taatggacgc ttagacccag ctattgattt
    20821 tattaaatca tatactgatg tagatgaggt gttaatacct tctgggaatg accagttaaa
    20881 tataataggt gatttcaaaa ataaaattaa agcgattaat gatatcggaa agtattcata
    20941 tataacgagt tcatatcaag agtttttaaa atatataaag tctatagaat cactagaaag
    21001 ctatagaggt gaatttagag aacctgtatt agcaagaata cataaatcaa ttggttctag
    21061 tagaatggat ataaaattag catgtgataa actagaaaac aagctgatta aaagaataga
    21121 gccattatta gtaattgcta aaaagagtaa aattgaaata agcaatcagt tacttataaa
    21181 tacatggaaa aaacttttgg aaggacaagc acacgatagt ttagctggat gtgtaactga
    21241 tactgtaaca gatgatattc ttcaccgtat aagagaagca aatgaaatat gtgacagtat
    21301 tgaaaatact attgtaaaaa agatttcaga agggcttaaa ttatctaaaa atgatatttt
    21361 agtattcaat acagaagcta agcgttttaa tggatataaa gagatacaag ttgtaagtga
    21421 tagtaaaaat atttatttta aagataattt agatgctact ataattgaag aaacttatgt
    21481 aaaaccgaga gaaaatgtat tagaagaaac acctgctggt aatatattta ttgaagaacc
    21541 aggatattat atattaaaag taagaataaa tatacagctt cctgcacttg gttataaagt
    21601 tgttagtttt gaattaagtg ataaagaaat ggtgtcactt gataaatcta atgacacttt
    21661 tatatctaat gataattata agataatata tgaagatgga agcttaaatt tacaacttaa
    21721 agatggaact tacatatcaa actttttaac attaaaagat agtggtaatg caggtgatac
    21781 ctatgacttt tctccactaa aaaatgatga ggatataaaa ctttcgtttg ataaagtgta
    21841 tacagaaaaa gctttaggat atgaaaaaat ggtggttaaa ggtactactt tactaccact
    21901 tacattagaa gatagaaaaa acaaatatct taatgggaaa ttaaatgtaa aagtaagtat
    21961 tgtcttatct aaagaaaacc cattgatgga tgtaaaactt tgtgttgata acacgatata
    22021 taatcataga ctacgtgttc atataaaaac tgatataaaa gataataaaa acatagcatc
    22081 attgccattt ggatatataa caagagaaaa tggagtttta gacaactggg aagatattta
    22141 cagtgaaatg cctatagatt tagaaccttt ggaaagtaat attacgctta caaaccaaaa
    22201 tagaagttgt actgtattta ctagaggaat aaaagagtat caacatattg aagatgaaat
    22261 tgcattgacc ttacttgcta ctacagatga actaggaaag cctgatttat tatatagacc
    22321 aggacgtgct tctggagata caactaaaaa aggtcatata agaattaaaa cagataaagc
    22381 tcaaatgctt aaggaattag aattttcatt tgcaatatat atggattcta aatcatttga
    22441 tgaattggaa attgcgaatt taacccacaa ttatctaaga gaatgtgtaa attatcaatt
    22501 acaggattac aatttctttt tatatcgtat agataataag attcaaaaat caattgtcaa
    22561 taaaactgta agtagagaat tagaaataat atctttacca gaaaactatc ttatatcagc
    22621 atgttatcct tcttattaca gtaaagataa atttataata agagtggaaa atccgagtag
    22681 taatagaatg atattggatg agcaaatatt taaaaataga aatgggaaaa ttgtaaatgc
    22741 aatagaagat gtagaagaag aacaggtata tgaaatagca ccttttgacg ttatttcaat
    22801 actattggat ttataagtgt aaaagtaagt ttattgttta aagtctgaca gatattaatc
    22861 tgccagactt tttaatttgt ataaatttgg gtaaatatta atgaatggtt ttagtattta
    22921 agtatgaatt tagtatttaa tatagaattt attgaagtag aataattagt ttaacaggat
    22981 aagcagttta aataaagaat tattatatta gagtgatttt atatataatt taaaataata
    23041 aaattttaat aaaatgagtg aaagattgta tattaataga gttgatgtag ttacaaaaaa
    23101 gttactaatt gttatgtatt tacaaaactg atatattaat tacataaaat ctaaaatagt
    23161 ttgtaatagg agtatatata ataaaaattt taattaaata aagctaggta tatttataat
    23221 attaataaat atattgctat aaaagtttgt ttaataaatt aaataaagaa aagaggagaa
    23281 taaaatgtac aacatagatg atatgatata taattgtcca gtagaagctt tatcaaatat
    23341 tttaggtaaa aaatgggtgg ctataattat atggaaaata caagaagata aaaaacgatt
    23401 tggagagcta caaagagcta taccagactg tagtaagaaa atgttagttc aacaactaga
    23461 ttttttaatt gaacagggga ttatagtcaa ccaaaaaaag ttggttaata atgttgtaga
    23521 gtcaacatat tttttaagtg aatcaggatt acgattgctt cctgtcatgg aaaaaatgat
    23581 tatgtggagc aataaaaatt taaattgtga taaatactaa aatttactct gtaagtaatg
    23641 aaaatttaat taagctatga gtagaaaaat gtattaaaat tacataattt tttagttaga
    23701 ttttaattta gaaataggat tgtaatattg gaaataaaat aaggaggaat tttaatttgc
    23761 aaaatgtaaa tttattttta gtatttatag aaggtatagt atcattcttt tcaccatgta
    23821 tactgccaat tttacctatt tatttgagta tattgtcaaa tagtagtgta gaaaatttaa
    23881 aagaaggaaa gacgagtttt ataggaagtt ctttatttaa aaatactata ttttttgctc
    23941 ttggaatctc aacaacattc tttatattgg gttcatcagt aaaagtattg agtatgtttt
    24001 ttaatgaaaa taaagattta ataatgttta ttggtgggat tataattatt atcatgggat
    24061 tattttacat gggaataatt aaatcttcaa tattgaatag agaaaaaaga tttaatgtta
    24121 agtttaaaga aatgaaagca ataacagctt ttatattagg ttttacgttt agttttggat
    24181 ggacaccttg tattggtcca atattggcat ctgtattagt catggtttca agttcaagta
    24241 atcatcttag tgccaatctt ttaatagcag tatatactat tggttttatt ttgccattca
    24301 taattacagc tatgttttac agtaaactat ttaaaactat agataagata agatctaaca
    24361 tggaaattat taaaaaaata ggtgggatta tacttatagt atcaggaata ttaatgatgg
    24421 taaatggatt tggaagtata agcaaacact ttaatacgtc acaaaatagt aaaattgaaa
    24481 gcaagcaaga agaaaataag cgagaaaatt ctactgataa agaagaaaat tctgatggta
    24541 atgatagtca aaaagactct aataatgaca ataatgataa agggtctaat gatgaagata
    24601 gaataaagtc tattgatttt actttaacag accagtatgg taaaacacat aaattaagtg
    24661 attatgaagg caaagttgta ttcttaaatt tctgggctac atggtgtcct ccatgcaaag
    24721 aagaaatgcc ttatatagaa caactgtata aagactataa taaaaataat gatgatgtag
    24781 taattttagg agtagcttca cctaatttag gtagagaagg ttcaagggaa catgtagtta
    24841 acttcttaaa agaccaaggt tatacattcc ctgttgtact tgatgaagat ggagcattag
    24901 catatcaata tggaattaat gcttttccaa ctacatttat aattgacaag gaaggatatg
    24961 taactcagta tattccagga gctatggata aggcaactat ggcatcattt attgaaaatc
    25021 agagaaataa ataaaagtat ttaagtataa gtttataaat caatttaagg ttacaaaaaa
    25081 gtgcctaatt gtaccaccta aataatcttg ttatagtaaa agtataaaca atacaagaaa
    25141 gggttgaatt ttatatgaaa aaaacatttg atgctataat aataggattt ggaaaaggtg
    25201 gaaaaacatt agcaggggat ttggcaaaca ggggattaaa agtagcttta atagaaaagt
    25261 caaacaagat gtatggtgga acatgtgtaa atgtggcatg tataccaaca aaaagcttag
    25321 aaaattcagc aaacagcgta aaaacaaaga atataaattc ttgggatgaa gtacaagctg
    25381 aatatgagaa agctatagat aaaaaagaaa ctttaattac aaaactcaga gaagctaact
    25441 ataataaatt aaattcaaat gagaatgtaa ctatattcac aggaatggga actttcattg
    25501 atgaaaaaac agttcaagtc aaaactgaaa atgaaattta tgagttagta gcagataata
    25561 tatttattaa tactggttca agaccattta tacctaatat taagggaatt gaaaataaga
    25621 atatagtata tgatagtgag tctcttatga atctaagaac tttacctaaa aaaatgacaa
    25681 ttataggagc tggatttata ggtttagaat ttgctggtat ttatagttca tttggagcag
    25741 aagttacaat attaaactct aataatggca ttttaccaaa tgaagatgtt gaggattcag
    25801 aagaaataat aaaattactt gcaaagagaa atgtaaaaat tgttaataat gcaaatataa
    25861 aagagattaa agaagtttct gaattagcaa tagtagaata tgaagtagat ggtaaatcta
    25921 aagaattaac aagtaatatg atacttgtag ctacaggaag aaaagcaaac actgaagggc
    25981 tagggctaga aaatgcaggt atagaattaa atgaaagagg atttattaaa gtctcagaaa
    26041 ctcttaagac taataaagag catatatggg ctataggaga tataaatgga ggtccacaat
    26101 ttacttatat ttcattggat gattatcgca tagttattaa tcagttattt ggagataaga
    26161 ctagaacaac taatgataga aagaatatcc caaattctat atttataagt ccagcatttt
    26221 caagagttgg tcttaatgtt aagcaagcta aagaaaaagg atatgaagta ttagtggcaa
    26281 agatgccagt agaagcaatt ccaagagcta aacagattgg caaggcagat gggtttataa
    26341 aaatagtgat agataaaaaa tccaataaga tacttggagc tagtatgata tgtgaaaatt
    26401 caagtgagat tatccatctt attcaattag ctgtagattt agaagtagag tatacatatt
    26461 taagagaccg tgtttatgca catccaacta tgacagaagc tcttaatgat attctatctc
    26521 ctaatatgat aaaagaagta taacataagt ttaatatata aacctaaaat tatcattata
    26581 agtagatttt agaaagaggc tatctcaaaa aatagagata agtctctttt ttactgttta
    26641 aatgataaaa atatatttga ttttataaaa gaagattatc ttatgaacta aaaagtttat
    26701 tttaaaacac tacctattta tgttataaac ttataaatat aatatagaat ctattattct
    26761 gtattattaa gtggggttaa gcgttataat taattataaa tattgaataa tctaaatgga
    26821 taagataatg gtattaaaaa ttatcttaaa aggtgaaata atctgtattt aatgtagtac
    26881 agttatatct ttaaagcaag gtggtgaaat gatataaata agatatctaa aagagggttt
    26941 gatgatagtg ataaaagatg gttttcaagt aaagaattaa caagacttat aaaggctaaa
    27001 gaagaaatag aatggttatt aaatagggat tacaaaatag acccagtcgt tacttttgtt
    27061 ggtgatagat atcagttttc tataagacaa agagatgcat taaaaagggc agtctgtact
    27121 gatgaaaaaa atattataag acaatcaaag aggctttctc tagataaaat caaagaagat
    27181 accgtaaata tagatggctt taatttgata atatccatag aggtagcatt atctggtggt
    27241 actctagtaa taggaagtga tggcaatata agagatttag caggtcttag gggaacctat
    27301 aagattatag ataaaacaga agaagctttg aatctgatag gtaaattttt taataaatac
    27361 aatgcacaga atcttaaatt ttatttagat gctccagttt ctaattcagg aaatttaaag
    27421 tataggatat tagagcatgc caaaacttgg ggaattgaaa ctgaagtaga attagtaaaa
    27481 aatgcagatg ttgtattgga aaaattagat agagtagtta gtagtgatgc agtcatagtt
    27541 gacaagtgta taagttattt taatgtggct agaggtataa ttgaagagta tattaaagaa
    27601 tgtaatatca taaatttaaa taaatagata aatataggtg agaatatata agtatatgta
    27661 gcaatattat tagtaataca agtaaagttt gaaaatagga gaacgaatac atatcgaatt
    27721 tcataaaatg ttgtaaaaag acatatgaga ggatggatat gtgtgaaatt aactaaacta
    27781 aatattaaaa aatatagagc acctatatat aaatatgctt tagcaaatgt aaatttgagg
    27841 tctgctaaat ctaccaattc aagtatcata acagtaatac ctcagggagc taaaatggaa
    27901 gtattggatg aagaagatga ctggattaag gtgatgtaca attctcaaga aggatatgtg
    27961 tataaggatt tggtatcagt aagcgaatat gcttggagta acttaaactt aagagaagat
    28021 aaatctacaa cttccaatat aattacagta attcctgaaa aatctagggt tgaagtcctt
    28081 caagtagatg gagattggag taaggttgta tatgatgata aaataggata tgtttttaat
    28141 tattttttat caattgatgg gaataaacca aatgaattag attataagta tttttatact
    28201 gacatgatta aatttgttaa cgaaaataat attaaaagta ctagcgatta tctaattgta
    28261 acagacctta gaaataaata tacttatatt tttaagaaag ataatggagg ctggggacaa
    28321 ctttacaagt ggcaatgtac tataggtaag cctgagactc caactataac aggtatattt
    28381 tatataagtg gaagaaaacc ttcttttgga acggatgagt attcagttaa atatgctact
    28441 agaattaaag gtggatatta ctatcattct gtgctatatg attcaacagg aagttatata
    28501 atagatggca gacttggtga agctcttagt catggatgta taagattaag tacggaaaat
    28561 gcaaagtgga tatatgataa tataccagat acaacaacag ttataattca ttaagaaaaa
    28621 ttttgagttt tttattggga taatgattct taaattaata ggattatata ttaacttctc
    28681 ataaagagta ctatttaaaa agtgtaataa gagaatgcta ttaacaaaac aaagatattt
    28741 tgaggcactc tcttataaat atacataatt aagatatttt cataaacaat tctataatct
    28801 tatctttatc aaagaaaaca ggattagcac cagcacaagc atctttcata gagttttctg
    28861 caagcaattc aaaattagga ttatcaacac ctacatcttt taaagatttt gggattccaa
    28921 cctcttcaga aagagctttt atcttatcta ttacaaagtc aacacactct ttatctgatt
    28981 tattatttac atccattcca ataacttcag ctattggtcg gaatttggca ggggctgatt
    29041 tagcattttc ctcctcaact attggaagta gcatggcatt acatactcca tgaggtaaat
    29101 catataaacc tcctaattga tgagccatag catgtacatt tccaagacct gcattactaa
    29161 aggcaattcc atttaaaaaa caagcataac acatttgttc tctagcttct atgtcattac
    29221 catttttaac agctcttgga aggtatttaa atatctgctt tatagcatat aaggcagttg
    29281 aatctgtaac atcataagca ccattagcta ctacagcttc tatagcatga gttagtgcat
    29341 ccataccagt tgctgctgtt aaattagatg gtttgctaat cattaattct gggtcattta
    29401 ctgtcattgt agctagtgaa ttggtatcaa ccattatcat ctttacatgt ctgtcttcat
    29461 cagttataac atagtttatt gtaacttcag cagatgtacc agcagtagta gttatagcta
    29521 tgataggaag acatttttta gaagttttgt tgataccttc atagtctcta atatctcctc
    29581 cattagtggc taatatagag atagctttac cacagtcttg tggagaacca cctcctatag
    29641 ttataacgaa gtcgcaattt tctgatttca atattttaag tcctttattc acattagtta
    29701 cagttggatt ttgtttaact tcatcataaa caacaaagtc tacatctatc tgagataaaa
    29761 tatctgttac tttttttaca gtaccatttg aaactagaaa tttatcacta acaataaatg
    29821 cttttttagt tcctaatgat ttaattgaat ctttagcttc attaagacat cctttcccaa
    29881 gtaaatttat tggtggtaca taataaatgc tcataactaa aatctccttt tattttcatt
    29941 gatttttatg taaaaatata tatctaacaa ttttcactaa tttactcata atatatcgta
    30001 tcttagattg agatagggtt gctggttctt atataagaac ttaattcgta attacgatta
    30061 tgattagaat ttaacatagt atttttatca tgtcaataaa aatataaaaa atattataaa
    30121 aaaaaacaaa gttactgtag ttaaatcagc aactttgttt ttatagtata aatcaaataa
    30181 atacattagt ttaaaacaaa atttttaatt attatgtttt gatatcttcc atatacagaa
    30241 tattaatcta atttattaca atgtcttcat tacgttcttc catcattgat tgaatatttt
    30301 tctgagcatt taagagtaat ttttttatca gttctatttt ttcgtcatta gctctaaata
    30361 aaggcagtgt tacactaaca gcagctctta tacatccatt ttttcttatt ggtacggcaa
    30421 gacattttag gtgttccatt gattcctcac actctgaagc tatttgtgtt ctttgaactt
    30481 caagaagctg gtcgtataaa acatcaaaat ctgtaattga tttttctgta aaacctttta
    30541 gaccatctgg atataagctt attagttttt ccttgtcaaa atcacataaa agagcttttc
    30601 caagacctgt acaattagca ggtatttttt ttccaacata agaaataagt ctaattggtt
    30661 ctggagaatc tacttttcca atataaagaa cttcattatt gtcaagtata ccaagctgac
    30721 aagtttcaga acaggaatta actatattag tcatttcgtc aattatatag ttaaaaatag
    30781 ttcttttttc aaaaaatgaa gaccctaatg tgtaagaacg tatccctata gaatatttgg
    30841 atgtgttttt atcaatagta atgtattttc tagcattaag tgtatgaact ataggaaaga
    30901 tgctactttt tggagcattg ataacatctg ctatttctgt aagagtatat ccattttcgg
    30961 attctgctaa tgcttctaaa atatctaata tcctagctgt tgggcgatga ttatctgaag
    31021 tcataaattt ccccctcttt ttattaattt aaagtattag aatatgttga ttttagcaca
    31081 ctatacgata ttttacaatg tagaaaataa atatgtaaat ttatatataa ataagctctt
    31141 gatttagata cagatagata tttttttagg ctgtacatta aggaataact aatttccaaa
    31201 atatacctaa agaaagtaag tgatatttag ttatataatt taagtaaata tatgcaatag
    31261 tgatttttat atgtaaatat caaaatatta tgaacttata ttttatctat tttttacact
    31321 gtataaaaac tttatagttt tgaatactat ataattttaa atacgctgta tttttgcata
    31381 taaggaagtc atttgataat atacaaggta ttatcagaaa gtttgaaaaa attttgacaa
    31441 aaatttattt tttttattga ctcataaata ggaaaatgct atcattaatt caaagattcg
    31501 taattaaaaa tctagttctt aaatacgaac cgaaacggcc gttagaatta aagctaaaaa
    31561 cttaataaga gtaattaaat atcatgtttt aggaggatta actttatgat aatggatttt
    31621 attaaaaaaa ttcctgcagg tatgatgata gtgccaatgt ttatagcagc tttcattaat
    31681 accttttgcc cagatattgt acaaataggt tcgtttacga cagcagtatt ttcaagtgtt
    31741 gggtctgcaa ctataattgg ggttcaactg gtatgcttgg gaactcagct tcaatttaga
    31801 gaaatgccaa aagttttaaa gagaggtggt atacttcttg gttctaaatt tgctataggt
    31861 gctttgatag gtatacttat aggaaagcta tttggaatgg atggtgtcct tggtctgaca
    31921 acattggctg ttataagtgc agttacaaat agtaatggta gtatatatct ttcattgatg
    31981 acttcatatg gagatgaaac agattgtgca actatgagtt tacttacttt aaatgatgga
    32041 ccatttttta cattaatagc tcttgggact tcaggtcttg caaatgtacc attgttgtca
    32101 ttattggctg caatagtgcc aatacttgtt ggtatgataa taggaaattt tgacaaaaaa
    32161 atgaaagagt ttttagagcc agggtgtaat ttactcgtac cttttgtagg gtttgcactt
    32221 ggtagtagca taaatcttgc aagtatacta aaaggaggtt tatcaggagt attacttgga
    32281 ttaatatctg tatttgtagg aggtatattt atagtattct gtgataaatt tataggaaaa
    32341 cgtccaggat atgcaggatg ggctgtagct acaactgctg gaaatgcaat tgctgtacct
    32401 gctgctgttg cattagttga cccatcatgg caaccatatg ttgcaacagc tacaacacaa
    32461 gtggcagccg cagtagttgt cactgcaata ttagtacctc ttataactag ttggtgggct
    32521 aagaagtatg gatgtcctaa gttcccaaaa caaaatgagg atggtacaat aacagcttaa
    32581 tttatattac agtgagttgt tggtaaaata ataaattctt taattagatt ttaggatatt
    32641 aataaaatta tattatttat aaaggagagc aagaataatg ataaatgcag tgataattga
    32701 tgaaaaagat aatgttgcag tagctattga agcaatagct aaaggtagtg aaattagttt
    32761 taaattaaaa gacaaaacag taaaaacgat tacagcacta gatgatataa ctatttatca
    32821 taaattggct ataaaagata tggccaaagg tgataaagtt actaaatatg gtgaacatat
    32881 aggagaagca aatcaggaaa taaaaagtgg tcaacatgta catattcata atgttagaag
    32941 tgttagagag gatttggata aacaagttat gactaatata taaaataata tttatagagt
    33001 tataaaagtt gtattcattg cttttagtgt caaatagttt ttaaataggt ttttagctgt
    33061 ttgattagtg agtgtaataa aaattataat atataaaaat tataaaaagt atatagacta
    33121 ttttaggagg aaatcagtat gaaattttat ggatataaaa gaccagatgg aagagttggt
    33181 ataagaaacc acatattaat cttgcctacg agtgtgtgtg catcagatac aactagaata
    33241 atagcatcac aagttcaagg ggcagttacc tttaataatc agaatggatg ttcacaagta
    33301 cattcagacc aacaattaac tatggatgtt atggctggtt atgcagcaaa tccaaatgta
    33361 tatggtgtaa tagttgtatc tttgggatgc gaaaattgcc aaaatgattt ggtagttgat
    33421 gcaataaaag agagaacaaa taagccaata aaaactcttg taatacaaga agaacatgga
    33481 actttaaaaa ctatagaaaa agctgttcgt tatgctagag aaatggcaca agaagcttct
    33541 ttgcttagaa aagaagaatt tccaatatct gaacttatac taggaactga atgtggtggg
    33601 tctgacccaa caagtggatt agcagcaaat ccattaatag gtgaattaag tgataaactt
    33661 gtcgatttag gagcaacatc aattttaagt gaaactactg aatttatagg tgcagagcat
    33721 atactagcta ggagagcagt aaatgaagaa gtaaaagaaa aaatattaca tatagtacat
    33781 agatatgaaa attcattaaa attggttgga gaagaagtta gagaaggtaa tccatctcct
    33841 ggaaatatag ctggtggttt aacaagttta gaagaaaaat cacttggttg tatacataaa
    33901 ggtggtcata gacaaataag tgaagtatat gattatgcca aacaaattga taagaaaggc
    33961 cttgttataa tggatacccc tggaaatgat gcttcatctg ttgctggtat ggtagcagga
    34021 ggagcacaaa tagtggtatt tagtacagga agaggaacac catcaggaaa tccaatagca
    34081 ccagtaataa aaataactgg aaataaaata acttttgcaa atatggaaga taatatggat
    34141 tttgatgcta gtccagttat atatggtcca caaacaatgg aagaattaac agatgatttg
    34201 ttaaatatgg ttgtagatgt agcaaatgga aaacaatcaa aagcagagtc ccttggatat
    34261 actgaaatgg caatagctag agtatgcaac tatgtataat ctttaagtaa gaaaataaat
    34321 acatagaatt ttaataaagg gtgagattat gaagtttgta agttttactg aaggagaaaa
    34381 tgaatgtaaa agaactggag ttttttctaa agatgaatta tttattatag atgttaactc
    34441 tttaaatctc agtagaaatt ttaaggattt aaatgaatta attcaaaatg tatctagtga
    34501 agatattatt aagttgaaaa ctattataaa tgaaagtaca ttctataatt atgatgtttt
    34561 taaaagagag agatgtactg tacatgttcc tatagaaaaa ccaatacatg atatcttatg
    34621 tgtgggagtg aactataaag accatcttga agaaactcaa actcactttg atgatagttt
    34681 tgaagaacca caaaaaacgg tttattttac aaaacgtgtg acaaaggcaa taggtccaga
    34741 agatgagata gatggtcatt ttgagataaa taatcaacta gactatgaag ttgaacttgg
    34801 agtagtaata ggtaaaacag gtgttaatat tagaaaagaa gaggtagaag attatatctt
    34861 tggttacact gttataaatg atatttctgc tagaaagttg caaaaagaac atgttcaatg
    34921 gtttagagga aaaggattag atacatttac ctctttaggt ccatgtattt tacataaaag
    34981 tgcagttcct tttcctataa aacttaaagt atgtagtagg gtaaatggtg aagaaagaca
    35041 aagttctaat acaggattat tcatatcaga cgtttcagac atagtttcag aactttcaaa
    35101 aggtatgacc ttagaggctg gagacattat agctactgga acaccttctg gagtagggat
    35161 gggattttca cctcctcgat atatgagtag tggagatgta gttgaatgtg agattgagag
    35221 tattggaatt ttaaaaaatt acattaagta actgttttaa tataattaat attaaagcta
    35281 aatctgatgt attaatgaac atattaaaat aaattttagg agtttaaatt atgaaagcag
    35341 aatttttgac accagttgtt acaatatttg atgaagaagg aaatttagat aaagaaggta
    35401 ataaaaaagt gtatgaccat cttatagatg gaggtgtaga tggactagtc ataatgggaa
    35461 gtactggaga gttctttaat atgtctatgg atatgcaaaa agaacttata gatttagtaa
    35521 ctagtcatgt aaataagaga gtaaaagtgt ttataggtac aagtcgtatg tgtataaatg
    35581 aatctataga actttcaaac tatgcacata atagtggagc agatggtgtt atgataataa
    35641 gcccttatta tttctctctt gatgatgata gtattgagtt attttatagt gaaatagcta
    35701 agaatacaga ggctgaaata tatttgtaca attatccaga tagaactggt tatgatttaa
    35761 gtccagaact tacattaaga cttgcaagaa aacataaaaa catagttgga tataaggata
    35821 cagtaacttt gatgggacat accagagatt taataaatac tatgaaaata gagttcccag
    35881 aatttaaggt ttatagcggt tatgatgaaa actttataca taatctaatg tctgggggag
    35941 caggttgtat agggggatta tcaaatttaa ttccagaagt ttgctccaaa tgggctgaag
    36001 cttacaataa tagagatatg gagaaggtta tagaaattca aaaatatatt aataaagcaa
    36061 tggattttta cttaataacc aatccattta taccagcaat gaaaaaagct atgaatatca
    36121 gagggttaca aataagtgat tatatgactg ctccatttgt aaaaccaaat gaaaaacaag
    36181 tatgtgaaat taaaaaattg atgaatgaat taaatatatg ttaaatcaac cttgcaaaga
    36241 ggtcaacaat aaattacaat tatcttaata aaaattaaat taaaataata ctagggtact
    36301 atattagttt aatagggaaa gtgatgaaaa ttcactacag cccccgctac tgtatacgga
    36361 tacgaaatca aaatccactg aaatttataa aaattttggg aagggtgatg gaggaaaagc
    36421 cgtgagtcag gagacctgcc cagtattata taagttcaat ttagggtgga gattgtaatt
    36481 tataataaaa tgaagtatca attcgttttt gtaaagttga tatatgaact tctccttatt
    36541 aaattaggag aagtttttta ttttattaaa aggttatact tattaaagat gactttagga
    36601 taactttaat aagtatactt taaaaagcat atattattaa agttttttag ccactcataa
    36661 aaaataagat attggagtga aagagatgaa atttaaatca aatgttttaa agcagttttt
    36721 tttaattgct atggtaattt ttatggtagg aggtcttata gggtgtagta aaagtgacaa
    36781 agagaataaa caagctagta ctggtaagaa attagaatta aaatatgcta gtggatttag
    36841 tgttgaagat ttagaagatg gaattaaaaa agtaactgat ggagataatc gagaactgat
    36901 tttaatccca aagaagatta aaattcctga aaaatataaa aatgctaata tagttagaac
    36961 gcctgtggac aatgtattaa tagcatctac aacacaggct tgttctctga gaacaataga
    37021 tgaactagat agtataaaag cagtaacaac agaagagcag tactggacta ttaaagaaat
    37081 taaagattta atgaaagatg gaaaaataca ttacgttggt tcaaatttag caccagatta
    37141 tgaaaaaata gtagacttaa atcctgactt aactatagtt agtagtggtt tatcagaggc
    37201 tgatacaaaa tttattgaca aattaaaaga attagggctt aattatgttg tagacaatga
    37261 gtataaagag caaaatccat ttggaagaat ggagtggaca agtttaatag ctgcatttta
    37321 tgataaagaa gatatggcta ctagtgaact aaataaaact gtacaaaagg tagaagaagt
    37381 aagtaaaaaa ataaaaaaca aagctaaacc taaagttgta tgggcatctg tatatgaagg
    37441 aagtgcttat atagctccta aagattcata tgtggataat atgataaaaa tggctggtgg
    37501 aataaatgca tgtgcttcaa tagattcaaa tgaagggcga gtaagtattg aacaattgca
    37561 tgaagttgca aaagatgcag atatatttgt atactcatca agttcagatt atgcaccaaa
    37621 tttagattct ataaaatcta gtgcacctgt attggctgat ttggatgttg taaaaaacgg
    37681 aaacctatgg gtgtttgctc cagattatta tcaatcagta gataagacag acgaattaat
    37741 agtagattta gttgagatgt tccacccagg tactacaggt gaaaaaatca aacattatat
    37801 aaattatgat aaatagtaca gagaggacac aaaaagatag gttttataga ttttagttaa
    37861 tatagctttg ctaagaggag tatacaaatg gattttatca ataaaatgag aataaggaat
    37921 acgacaatat ttatagtatt aattataagt atgatactta cttttttagt gtgtgtagca
    37981 tttggctctg taaaaattga atttaaagaa gtaatagatg ttgtattaag aggtatggat
    38041 aatacagaac attataaaat aatatacaat ataagaatcc ctagagtact tgcaaccatg
    38101 gtaggtggag catgcctagc agtatcaggt attttattac agatattttt taaaaaccca
    38161 atagttgaac cgtatatatt aggagtatct tcgggttcta ctttatcagt agctctcatg
    38221 attttgggag gatacacatt gggatttgag agtgtaaatt caatgagtat atttgtagca
    38281 gcttttatag gagctttaat tgtaatgtct atagtcattt tatttgcaaa taaggtaaag
    38341 aatataacaa ctcttttaat aataggaatt atgaccggat atgtatgtag tggtataaca
    38401 aatgtgttac aatcatttgc aaatagtgat aaattaaaag aatttactat gtggtctatg
    38461 ggaagttttt ctggatttac atgggaaaag gtagaaatac ttataatagt tggtatatta
    38521 ggtcttttga tgactgtatt cataataaaa cctttaaatg cttttttact aggagaagag
    38581 tatgcaaaaa gtattggcat aaatataaga ttttttagag ttttgatagt atttatatct
    38641 agtatattag cagcaatagt atcagcattt gcaggaccta tagggtttat tggacttgca
    38701 gtgccacaaa tttcaaaaat gatatttaaa acatcagata atagagtttt gataccagta
    38761 gtaatatttt taggcagtat agttacagct ctttgtgatt taatatcaag agtaatttta
    38821 tcaccagtag aattaccaat aagtacgata acatctttat taggagctcc aattgtagta
    38881 atgttattgg tgaaaaggaa ggatagggct tagacatgtt gaaaactaat aatttaagtg
    38941 taggatacaa taacaaagtt gttataagta atataaatgt agaagtaaaa aatggagaaa
    39001 tactatgtct tttgggaagt aatggagctg gaaaaactac cctattaagg tccttatcta
    39061 aacttatatc accaataaaa ggtgaaatat atttgaatgg tgtaaacata aattgtatat
    39121 caagaaaagc attatcaaaa aaaatggctt tagtacttac aaatagatta ttaggtgatt
    39181 taatgactgt acaagatata gtcaatatag gaaggtatcc atatacagga ttttttggga
    39241 gtctatctaa gaaagattta ataatggtag atgaagcatt ggagtctgta gatgccttac
    39301 atttaaagaa aagatatttt gatgaactaa gtgatggaga aaaacaaaag gtgttggttg
    39361 caagggctct tgttcaagaa ccagaaataa ttatattaga tgagcctaca actcacttgg
    39421 atataaaaca tagattggaa ctcataaaca tactgaaaaa attaagtaaa gaaaagtcaa
    39481 tatcagtaat actttcattg catgaaatag acatagcatt aaaaagttgt gataaagttg
    39541 ctcttataaa aaataataaa gtcatagctt atggtcagcc tgaagatgta gtagatgagg
    39601 atattataaa ttcgctttat gaattggatg ataaaaactt taatagtctt ttaggttcag
    39661 tagaaattag taataaatct aaaaatgaag tttttataat tggtggtggg ggtaaagcaa
    39721 caccaattta tagagctttt actaaaaaag gtataggtct gtattctgga ataatacatg
    39781 aaaatgatat tgattatgaa attggtagaa ctatggggat aaagatgttt acagaaaatc
    39841 catttgagcc tataagtgat gagagtttcg atttggctat tagaaattta aatgattcca
    39901 agattataat agatacagga tttagtgtag gagagacaaa taagaggaat atagatatta
    39961 taaaagaggc tttaaaattg gataaaaaag tttattcttt tagaaataga gatgagagta
    40021 agaagtatta tgacagtttg gatagtaaga tagaacatat agataaagtt tctcaaataa
    40081 tcaatagtgc agatataaat aatttattat aatttatgaa ataaaatgta cttatgtgct
    40141 atagaaaaaa gagtatagat tataattttt ttgaaattac aatctatact cttttgttat
    40201 tttgtttatg tatttatata tttataaaac tttagcattt tatagataac caatagcttc
    40261 ctctctagtt aaaaaaaagt gaatccctgt agtcgattct ttccatctat tttcattaaa
    40321 atcttcagct acaatcgttt ctcctactct atatataaaa ttttcatcag catatgcacg
    40381 agcactttta aaagattctt taccatctat actagtaatt gacagtactt ttgccttatc
    40441 acatctacaa gcgtttgatg tagcagacac tctttttgcg tcgctgggta ttaataattg
    40501 taccattcta aaattaaaac attttttata gcctataaat gctcctgttt caggacaata
    40561 caatttaaaa aaacgggtac tttcatctga tattactcca tttaaagtag catgttctaa
    40621 atttgaattt tctaaattag ctcctctaat atctgagtta gataagtcac aaaatctaaa
    40681 acttgcacca cttaagtctg cattttttaa tatagaattt tttaatgaac aatccgaaag
    40741 ataagaatta ttaaaaatag agttttctaa atctgctttt tctaaattta aattgataag
    40801 gtcagaccac gaaaagtcaa tattacttaa gcagtatcct cttaagtcca tattttctaa
    40861 tcttaattct tttaaatctg ccttttctcc agcattattg tttttaagcc ataaataatg
    40921 tttctcaagt gttttttcta attcttgttt agaaatagtt ttcattaaaa tcaccttcat
    40981 aaatttattt ttatatatgt agtagcaaaa tagtcatata tttaattata taacaataaa
    41041 taaaaaactt ctaaataata tataaaatat catcttgaaa gtactttttt caatatatca
    41101 gaatatattt ttaagctatt tagagataat ttaaattttt aaacaggaca taataagctt
    41161 gtattgtttt atatttgagt tgataaaaat ttctttaaat aaaaataatg tcaattataa
    41221 agtaataaaa gtttagatat aaaaaaattt gtgtatatac tatatgtagt atataataga
    41281 taaagcactg actatatgta gtgcttttgt ttttgaaaaa tacttattgc atttctataa
    41341 ttatagatta attttgggat ttcaactgat aagtaccaaa agaaataata agcaaattaa
    41401 gtgaaattat ggcacaagat tatgttaaaa ggacggtaaa taatgaattg gatagagctt
    41461 aacaatcaag tgataattaa aaatgaacaa ggcaagtacc aattggaaaa ggataaggaa
    41521 gccttaagta gttacataga agcatttata cagccaaagt tgagaaaatt taataaccta
    41581 gaagaaagat tgaagtattt aatagatgaa ggttattatt caaaagaagt aataaatcag
    41641 tatagcatag atgttattaa aaatatatat gatatgattg ataaacataa gtttgaattt
    41701 caatcatata tgagtgcaaa taagttttat caaaattatg cattaaagag caatgatgga
    41761 aaggaaatat tagaaacata taatgataaa gtgttaattg tagctttgac actaggaaat
    41821 ggcgataaag atttagcttt aaacttggca gataaaatag taaaacaaga atttcaacca
    41881 gctacaccta cttttttaaa tgctggaaga aaaagggctg gagaaatggt atcatgtttt
    41941 ttactatctg tagaagatag tacagaaggt atatcgtatg ctatatcttc atcaaatcac
    42001 ttatcaaaga ttggtggagg agttgcacta aatttatcta aacttagagc atctggcgaa
    42061 tctatcaaag atatagaagg tgcagctgga ggtgttgttg gagtagctaa aatgttagaa
    42121 caatcattta gttactttaa tcaaatggga gctagacaag gttctggtgc ggtgtacctt
    42181 actgtattcc atcctgattt tgaattgttg atggatacta aaaagataaa tgcagatgaa
    42241 aaaataaggc ttgctacatt atcattagga gctataatac cagataaatt tatggagttg
    42301 gcagaaaaaa atgaagtagc atatgcattt tatcctcata ctgtgtataa gaaatatgga
    42361 gtttctcttg atgagataga aatggatgag tggtatgata aattggttaa tgatagtgat
    42421 ataagaaaaa aagaaataaa tcctaggcag atgttgacaa aaatagcaca gatgcaacaa
    42481 gaaagtggat atccatatgt agtgtacata gatacagcta atagagaaca tacattaaaa
    42541 gatgttggaa ttattaaaat gtctaactta tgttgtgaga tatttcaata tcaaacacct
    42601 tcagaaatag agggatatgg aggaaaaaat gaatggggac aagatataag ttgtaaccta
    42661 ggttctttaa acatagccaa tgtaatggat aataaaacta tagaaagtac agttgaaaca
    42721 gcaataagag cactgtcatt tgtagcagat agcacagata taaaaccagt gccaacggta
    42781 agcaatagta acagcaagtc tcattctata ggattaggag ctatgaattt acatggatac
    42841 ttagtaagag aaaatatttt atatacttca gatgatgcta tagatttttc taatgtattt
    42901 tttgcaatgg ttagatacta ttcaattaaa gcttctatga aaatagctat agaaagaaat
    42961 caaacttttg aaggatttga taaatcagaa tatgttaagg gaagaaatag caaggtttta
    43021 tcaaaatact atgaacaatc ttatctacct aagtcagaaa aggtaagagc attatttgaa
    43081 gggatttata taccaacaaa agaagactgg acaaaattat tggatgaggt aaaagaaaaa
    43141 gggatatata atgcatattt aatggcagta gcaccaactc aaagcattag ttatgttcaa
    43201 aatgctacat caagtataat gccaattact gagccagtag aagtaagaac atatggagac
    43261 tctactacaa tatatccaat gccattttta acaaatgata atatgttgta ttatcaatca
    43321 gcatacagga tggatatgag aaaggtcata gatttagtgg caacagttca aaaccatgtt
    43381 gaccaaggta tatcaacaac actgtttgtt acagatgaaa agacaactag agatatagct
    43441 agacattaca tatatgccta taaaaaaggt ttgaaaagtt tatattacac aagaacaaag
    43501 atgacaagag atactcatga gtgtctagtg tgttcagtat agggagagaa atatatgaca
    43561 tttaatttac ataaaataca taatgcagtt aactggaata gagaagaaga tggatttaca
    43621 caagcttttt gggaacaaaa tgtaaaacaa ttttggcttc ctgaagaaat atctgtttct
    43681 aaagacataa aggtatggaa tgaactaagt aataaagaaa aggaattata taaaaaagta
    43741 ttgggtggtt taacattact ggatacaaaa cagggaaata atggaatacc atctatgatg
    43801 agtttaacag aaaacctaca aagaaaagct gtcttgtctt ttatggggac tatggaagaa
    43861 atacatgcaa aaagttattc ttctatattt atgactctac tttctaattt agaaatagat
    43921 gaattatttg aatggataga aacagaacca acattacaaa gaaaggctga tttagtttta
    43981 gctcaatacg aaaatactac aaatcaagag ggattatacc tatcaatggt tacaagtgta
    44041 tttttagaga gtttcttgtt ttattcagga ttcttttatc cattgtatct atctggtcaa
    44101 ggaaagatgg tagctagtgg agaaataata tcgcttattc ttagagatga gtctttacat
    44161 ggtaagtata taggattgct agcacaagaa atatacgatt catttgataa aatggataag
    44221 gagatgttag aagagaagat gtattctata ctttatagcc ttatggagaa tgagatagag
    44281 tatacaaatg ttatatacag agaaagtggg cttgaaaaag aggttgtaaa ctttttaaaa
    44341 tacaatgcga atagagcttt agaaaatcta gggtttgaga agctatatac tgtagatgct
    44401 ataaatccaa ttgtattaaa tggtcttagc actgaaacca aaacacatga tttcttttca
    44461 actaagggta atggatacca aaaaggagtg tatgaggaat tagaggatga agattttata
    44521 atataattta taattatgac acactgttgt cacttttagc gtgataatat caatgtataa
    44581 aatatatatg gaggtatttt tatgaaatat gaatggagaa aaagagataa agagttatat
    44641 ttacctaaaa agaatcctgt aatagttgaa ataccagaac agaaatttat catgttaaaa
    44701 gggagtggag acccaaattc taaagaattt actgaagcaa taggagtact ttattctttg
    44761 gcatatgcaa taaaaaccat gcctaaaaaa ggaattgtac cagaagggta ttttgactat
    44821 acggtttttc ctttagaagg tatatgggat aagggagaaa aaagtaaagg cttagatgta
    44881 cttattaaag aagatttaat ttacactata atgatacgtc agccagattt tgttacacaa
    44941 gacctgttgg ataaagctac tgatatagta aagaagaaaa aacctcataa tcttcttgaa
    45001 aaagttagat ttgggtctat taatgaaggg ctatgtgttc aaatgcttca tataggttca
    45061 tatgataatg aaccagaaag ctttgacatt atgaacgaat tttgcaaaaa aaataaactt
    45121 ataagaaaat cttacacaca tcgtgaaatt tatataagtg atgctagaaa agtatcgcct
    45181 gaatcattga agacggtttt acgttttgaa gtagaaaggg aagtataaat attttgaata
    45241 atttataaga gttataaaaa gtgaagtctg ttgagacttc attttttgat gcaattttaa
    45301 aattaaattt gatgtttcat aatattttaa aaactttcta cttttattag tgtgaataac
    45361 tgttgctatt aaataataat actaattata taagtattat tatataatat ttatagatta
    45421 ttatataagt a
//
LOCUS       DAEOTL010000027        44996 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEOTL010000027 DAEOTL010000000
VERSION     DAEOTL010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44996
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.027"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..186
                     /locus_tag="KRH82_001767"
     CDS             <1..186
                     /locus_tag="KRH82_001767"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655048.1"
                     /translation="DDFMYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVH
                     KFKLYVVNEKYIKGIME"
     gene            complement(344..997)
                     /locus_tag="KRH82_001768"
     CDS             complement(344..997)
                     /locus_tag="KRH82_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBG8655049.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            1158..1724
                     /locus_tag="KRH82_001769"
     CDS             1158..1724
                     /locus_tag="KRH82_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBG8655050.1"
                     /translation="MMNNELNTIILETLSNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDITKK"
     gene            complement(1864..2073)
                     /locus_tag="KRH82_001770"
     CDS             complement(1864..2073)
                     /locus_tag="KRH82_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655051.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(2149..2802)
                     /locus_tag="KRH82_001771"
     CDS             complement(2149..2802)
                     /locus_tag="KRH82_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBG8655052.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFISKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            complement(3291..4331)
                     /locus_tag="KRH82_001772"
     CDS             complement(3291..4331)
                     /locus_tag="KRH82_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBG8655053.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     IEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            complement(4438..5829)
                     /locus_tag="KRH82_001773"
     CDS             complement(4438..5829)
                     /locus_tag="KRH82_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8655054.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            complement(5948..7828)
                     /locus_tag="KRH82_001774"
     CDS             complement(5948..7828)
                     /locus_tag="KRH82_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655055.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAQITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            complement(7828..8574)
                     /locus_tag="KRH82_001775"
     CDS             complement(7828..8574)
                     /locus_tag="KRH82_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655056.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGESIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            complement(8721..10940)
                     /locus_tag="KRH82_001776"
     CDS             complement(8721..10940)
                     /locus_tag="KRH82_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8655057.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            complement(11306..12700)
                     /gene="gltA"
                     /locus_tag="KRH82_001777"
     CDS             complement(11306..12700)
                     /gene="gltA"
                     /locus_tag="KRH82_001777"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBG8655058.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            complement(12700..13593)
                     /locus_tag="KRH82_001778"
     CDS             complement(12700..13593)
                     /locus_tag="KRH82_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBG8655059.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            14219..15070
                     /locus_tag="KRH82_001779"
     CDS             14219..15070
                     /locus_tag="KRH82_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBG8655060.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNGLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(15203..16816)
                     /gene="ggt"
                     /locus_tag="KRH82_001780"
     CDS             complement(15203..16816)
                     /gene="ggt"
                     /locus_tag="KRH82_001780"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBG8655061.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGSVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(17041..18978)
                     /locus_tag="KRH82_001781"
     CDS             complement(17041..18978)
                     /locus_tag="KRH82_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655062.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLITISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(18965..19732)
                     /locus_tag="KRH82_001782"
     CDS             complement(18965..19732)
                     /locus_tag="KRH82_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655063.1"
                     /translation="MEEILYVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            20020..20694
                     /locus_tag="KRH82_001783"
     CDS             20020..20694
                     /locus_tag="KRH82_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655064.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            20718..21722
                     /locus_tag="KRH82_001784"
     CDS             20718..21722
                     /locus_tag="KRH82_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655065.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            21834..23063
                     /locus_tag="KRH82_001785"
     CDS             21834..23063
                     /locus_tag="KRH82_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBG8655066.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            23071..23745
                     /locus_tag="KRH82_001786"
     CDS             23071..23745
                     /locus_tag="KRH82_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655067.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            23748..24980
                     /locus_tag="KRH82_001787"
     CDS             23748..24980
                     /locus_tag="KRH82_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655068.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(25266..26531)
                     /locus_tag="KRH82_001788"
     CDS             complement(25266..26531)
                     /locus_tag="KRH82_001788"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBG8655069.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASKLGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(26584..27732)
                     /locus_tag="KRH82_001789"
     CDS             complement(26584..27732)
                     /locus_tag="KRH82_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBG8655070.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVSLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(27832..28377)
                     /locus_tag="KRH82_001790"
     CDS             complement(27832..28377)
                     /locus_tag="KRH82_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBG8655071.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(28600..29544)
                     /locus_tag="KRH82_001791"
     CDS             complement(28600..29544)
                     /locus_tag="KRH82_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBG8655072.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            29930..30811
                     /locus_tag="KRH82_001792"
     CDS             29930..30811
                     /locus_tag="KRH82_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBG8655073.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(30872..32080)
                     /locus_tag="KRH82_001793"
     CDS             complement(30872..32080)
                     /locus_tag="KRH82_001793"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBG8655074.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(32153..32405)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(32557..33546)
                     /locus_tag="KRH82_001794"
     CDS             complement(32557..33546)
                     /locus_tag="KRH82_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBG8655075.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            33698..34138
                     /locus_tag="KRH82_001795"
     CDS             33698..34138
                     /locus_tag="KRH82_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8655076.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            34465..34692
                     /locus_tag="KRH82_001796"
     CDS             34465..34692
                     /locus_tag="KRH82_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBG8655077.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            34718..36838
                     /gene="feoB"
                     /locus_tag="KRH82_001797"
     CDS             34718..36838
                     /gene="feoB"
                     /locus_tag="KRH82_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBG8655078.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(36971..37789)
                     /locus_tag="KRH82_001798"
     CDS             complement(36971..37789)
                     /locus_tag="KRH82_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8655079.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            37996..38280
                     /locus_tag="KRH82_001799"
     CDS             37996..38280
                     /locus_tag="KRH82_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655080.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   38448..38939
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=38515..38543
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(39598..41691)
                     /locus_tag="KRH82_001800"
     CDS             complement(39598..41691)
                     /locus_tag="KRH82_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8655081.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVKNPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLDIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SVQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     gene            42344..43267
                     /locus_tag="KRH82_001801"
     CDS             42344..43267
                     /locus_tag="KRH82_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBG8655082.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIESDNEQDDLVIQNFIDDLGNQFFIRDKDT
                     SATYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNILKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            43242..44069
                     /gene="panB"
                     /locus_tag="KRH82_001802"
     CDS             43242..44069
                     /gene="panB"
                     /locus_tag="KRH82_001802"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBG8655083.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            44088..44936
                     /locus_tag="KRH82_001803"
     CDS             44088..44936
                     /locus_tag="KRH82_001803"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBG8655084.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAI
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT        15847 a         6957 c         5253 g        16939 t
ORIGIN      
        1 gatgatttta tgtataaata tgatgactat gtgaatttaa caaatgattt agatttacct
       61 gtagaaatta gaaacaaatg tgtcagaatt gttagtgttt cagagaattt agaggatata
      121 attatagtac ataaattcaa actatatgtc gtaaatgaaa agtacattaa aggaattatg
      181 gaataggcat tttgaatgga ctatttttat caaaatttta ttataagtag aatttaatat
      241 ttataataag gaactgtctt attgtctaag atataatcta tataaggcag ttccatttta
      301 ttcattgtag aattttagta tcaattaatc aaatctttta aaactataaa acatacaata
      361 aaactgctaa aaagtgaaat aaagaaccta tcataataaa aatatgaaat atttcatgaa
      421 atccaaactc aggacttata ttaggctttt taattatata aataatcgca cctatagagt
      481 aagatacacc ttccataatt aatagtctaa ggcaatcctt aggaattgaa ttgaatgcat
      541 ttatatcaaa aacaattgcc caccccataa gtaaatatat actggtagat aaccatctag
      601 gtgcatccat ccaaaatatt tttattatta tgccaataaa tgcaactatc catattgctg
      661 taacaaatat tatgccttct tttttttcca taaaattcag acatattggt gtataagagc
      721 cagcaatcaa tacgtaaatc attgcatggt ctacttttct aaaaaacaat tcttgttctg
      781 gtgtcccctt taaaaaatga taatacgaac ttgcactata taaagcaatt agtgaaagtc
      841 caaatacaga tacagatact atcatcaaga gagaagtttc ctgtaatgta acagattgaa
      901 aaactaaaat tatagttgct aaaagagata aacaagcacc tataaaatga gttaaactgc
      961 ttattgggtc tctacccttt aaaaaaaatt gatacatttc gtcctcctac aattatgtat
     1021 tttaaaaatc agattcacaa atatagtttc cattactata ttatatattt aattatacca
     1081 ctttatgttt tttttacaag ccttaatatt gttttacttt ctaatttagt gtattatata
     1141 tattatggag gtaacatatg atgaataatg aacttaatac tataatacta gaaacactaa
     1201 gtaatgcaga tataacttca aacgatattc catctattga cttatatatg gatcaaatta
     1261 tttctctaat tgacaataag ctttctgcta ataaaagatt tgaaagtgat aaaattctta
     1321 ctaaaaccat gataaataat tacagcaaag agggattaat caaaccagtt aagggaaaaa
     1381 agtatactaa agaacaaatt ttacagatga taattattta ttctatgaaa aatacactta
     1441 caatacaaga aattaaaaga atcttacatg gtgtgtatga aaaggataat ttcagtgaaa
     1501 aagatttagt ttcatgttac gaaaaattca tgttaataaa agaaaatcaa agaaagaata
     1561 taccggactt tatagagtct aattttgaaa atattagtat aaatccagaa aataaagatg
     1621 atttattgat agccttatta agtctgactt caatggctga ccaattaaaa aatatttcag
     1681 aaaaattagt agacagatat tttccagaca taaccaaaaa ataattttaa taaagtaaga
     1741 ctgaaaataa atattaaaat acaatgttat ttaaataaac ttttattgta taaaatataa
     1801 ttttcagtct aaatattaac actttctatt tttaattcct tcaataattt ccattttaaa
     1861 attctacaaa tttaatttta ttctatttaa gttttgacaa tgtgaacaat ttaaattaat
     1921 ttggatttgt ttatacccta tgaaaacggc ttgttttaac gtaccagtgc catcatctat
     1981 catgactata ttatctttta tttctacaca gaaattattc tcttgattac accaataaca
     2041 atcatacttt tcattacttt tttcttctcg catgattctc gcctccttca atataagttt
     2101 ctacattaaa agaggttttt cctttatatt tttaataaaa tattataatt aaaatttcat
     2161 cccatctatt ataccatcta ttttttcaga tgctttttct attgcagctt gtctttcttc
     2221 ttcactagtt ccagttccat ctactaacaa ttcatcaaat tttttaattc ctataaattt
     2281 cataatactt tccacataat ttaacccttt attcataact ggcttcaaca cccatggtat
     2341 gtgtccacca gaagattgta tatataccat acttctatca atatcattta aaattccttg
     2401 tggtttatca ttgccttcaa aagatatagt ttttccatct tgaattatac aatctatata
     2461 ctctttaagt ggtgctggaa aagataaact ccacataggt gctgctatta catatacact
     2521 tgcactcaca aattggtcac aaagatttct aatctttgta agttcttttc tatccttatc
     2581 gtctaaattt ttagcatttt cttcactaac tatgctattt cttttttcaa agtactgata
     2641 ctcaagtctt ggtatatgtt ctttataaag gtctatctct tcaacctcaa aatctttatt
     2701 tttttccata aatttactta taaattttct tgctacagtt ttacttgaag ataagtcttc
     2761 aggttttgaa tttacattta tatataataa ttttttcttc ataagctcac tcctaagatt
     2821 attttatatt attatttcac aaatataccc attctattct tttgttgaat tataaaataa
     2881 ctattattac agaatgtaac ttatgttttt atacacatta cttctacttt tttactattt
     2941 atacttttac ccaaacaagt accatcttat aaacatatca actaaaatat tattctgcta
     3001 agtatcttta ttttataaaa aagtgtgaag ccacataatt tgttaattac taagcctcac
     3061 acttttatta tattttttct acatatactc ctaatatatt ctgtaatatt atatcttctc
     3121 atccaaaatt aattaccact gaggtatacc atataacgcc atttttcagt tcaaaaataa
     3181 tcaataaata aaattgatat tacttaagtt gttaaattat tgctcatgct aatgacatta
     3241 aaaatggtat agtgtaaaac actataccat tttagttatc taaacatttt ttaatatttt
     3301 ttcttccatt ttgcacttct tcctcttgca acaacttcta tcttatcttg ttttcttaga
     3361 ttattaaaaa ctctatttat agtaggttct ggaatgtcag gacataaatc tcttatatct
     3421 tcttttgtaa aatatccaag ggtagaattt attattttct ctattctact agtttttgtt
     3481 tgtcttttct tatcagatat atttaaacta tcatccagct tctcatatgc agttaatatc
     3541 gtctctaaaa aatactcaat ccatgcattc atatctgctt tttcactacc tattgaggct
     3601 ttcaaataat ttaaattact ataatattca tatgaactat catcaaatat ctttcctaaa
     3661 cttatatatc ttccaacttc atacccattt ttatttagta acaataggat aagtactctc
     3721 gccattttta tattaccttc tttgaatgga tgtatcaata tgaaatctaa cacaaatgca
     3781 gaaattaata ttaatatatc aatttcatct tcctctatca atgtattata agcttcacat
     3841 atttcttcta tagctttttc aactttattg acacttgaat cagtacttat aaattcgcta
     3901 ggttttaaat tgtgttcaat aaaatcatta tctgacttat aacttcctcc tctagtagat
     3961 gaaaatttat ataagtatcc atgaagctca agaatcgttt gtgaactgat gggaatactc
     4021 tcataagcac tgttaatagt ttttaccaca tctctgtatt caacaatact caattcctct
     4081 ctacttctag gtgtaacttc attacttatc aacttttcta gattaaaatt actactatct
     4141 ctttgatttc caatgtatgt agattcagaa caatctacta aagatttttt ttctaagttt
     4201 tctaaaattt cttttggttg ttttttgtaa agcagttgtc tacccttata ctcatttatc
     4261 ttagacaaca ttctagctac attcatgttt acatacatat tttttaattt gcttttcttt
     4321 gtaaattcca taaaatcact ccataattag aatttctctt atccttgaca gcggttttat
     4381 tttatcatat aatcgtattt tttgcaattt cttgctcaat tatctgaatt tatattttta
     4441 ctcagtagtt atctcgttta gtctttcatt ttcatttaat ttttcagttt taggagtata
     4501 tctttttaat tctctaaata caactatacc tgtaattact gtagctataa aatcagacac
     4561 tggttgagct gtccatacac cctgtaagcc taagaatgta ggaagaatta atactgctgg
     4621 tatcaataaa attacttgtc ttaaaaggct caataacata gccatttttg cttttcctat
     4681 agattgtata aagtttgttc ctgtaactga taagcctaca attggcaaca taagtaagta
     4741 tattcttaat ccattaacag atatattcat aagttcaggg tctttattaa atatacctat
     4801 aatagcttct gggaaaagca taactactac catacccata cataaaatta tagtagctac
     4861 tactaatgaa cctaaatatg cttttttaac cctatcatat ttttcagctc cataattgaa
     4921 acctataata ggttgcgctc cttgatttat tccaaagata ggcatcaaaa ataccattgc
     4981 aatagaagaa atagtagcca tagcccctat agctaaatct ccaccatgag ttttaagtgc
     5041 aatatttgat attacttgaa ctaaacttgc tgcaagttgc atagcaaatg gcgacatacc
     5101 tattgcaaac actgctttta ttagcttttt atctaatttt agattagatt tactgaatcg
     5161 taagtttgat tttccactta tataataccc tatagttaaa atagctgtaa gagcctgaga
     5221 agttactgta gcaattgcag ctccttgtat tcccaaattg aatccaaata ttaatatcca
     5281 gtctaaaact atattagtta aacatcctac tatcattatt cctgctgaaa ttttaggact
     5341 accatcagct cttattgagt ggtttaaaga aaaggaaaga agatttacta ctgtacctaa
     5401 taatataata tttatatatg attttgcata tattaaagta ttttcacttg ctccaaacaa
     5461 tgtaagtatt ttatttgcaa ataatattcc aagtatcatt atgataattc ctgttattac
     5521 agataacgtc attgcatttc ctataagttt tcttgcctct tctactttac cttgcccaag
     5581 ttttattgat atggtagtag tagttcctat acctatcaac atcccaaatg caagtattat
     5641 tgtcattatt ggcattgtta caccaagacc tgttattgca agtggtccaa cccctggtat
     5701 atttccaata aaaattctat ctactacatt atataaacta tttaccaaca tacctattat
     5761 agctggtata gaatatttta gtagtaattt actaattcgt tctgttccta ataattgttg
     5821 attttccatc aagtctcctc cttcttctaa tattcaattt tccacatatt acaagggagg
     5881 tgcaaatgcc ctcccctaat attaactact ttttaaatat taatttatat atctattata
     5941 taccacttta atcaaaaaac caaacttttc tagtataaat tttttttaat aagtaaaaat
     6001 aaagtgaata tatagatgat atcagtagta atatacccaa attttctaac ttaaaactat
     6061 tatttaatac ttgatttaaa aacagtaaag aaattatgct atttataatt gctataaaat
     6121 acggtataaa aaacaatgta cctatctcta tactaacaat cttattcata tttttaaaag
     6181 atagacctat ttttgatagt tttttgtact ttacattatc ttctatctcg tctgtatata
     6241 atctaaagta taaaaaacta aaaactgcta taaataatat cactcctata aaaacaccca
     6301 taaattgaag aattttactt tgttgtaact ctactaaata catatctggt aatgttaaaa
     6361 aatatgacct gttatattct ctatccaaat taaaatgttt ttcttttaaa ttttcagtta
     6421 tctgtgcact gctttgccag tttttataat caaatccatg aaaattaatt tttgaaaatt
     6481 caccttttac ttcattgtat aagtcatcac ttataactac aactttacta aacagtcctg
     6541 taggaaaaat tattttattt tttgattttt ttacttctat atttaaattt tttatactat
     6601 aattttttaa ttgttttaaa gaatttatat gttcttgcga attgctacta ggaattataa
     6661 tcccttcata tttttctaac tttgaactaa ttttatctaa tcccaattcc tttgataatt
     6721 tgttataatt ctttacactt agtaagactt ccctattata tttaagtaca ggaaaactta
     6781 actccttata atcatatcct ttgattgctt ctctaatttg ttgtagttct tcatattctt
     6841 tttcattatt atgctctgaa aaatatgagt aaaccattgg gaaattattt ttagaagctt
     6901 ctccttgaga acttacaagt gttgaagttg ttgtaaatgc tactaaagta gccgataaaa
     6961 gtattgttat taaaaataac aatcgtgtat tatcctttaa tttatatatc aaattactta
     7021 taagtaacat atttactttg ttcttataaa atttttcttt attttttaaa tactttaata
     7081 tcaaaatagt aaattgagaa aaaaataaaa atatccccaa agtaattaat agtgctgttg
     7141 tatacatacc tccatttatt tttaacttat tgccaaatag tatcatagca tatcctaata
     7201 taagacatat tacaccaatt attccaaata gctttgaaga ttttatctct tttttaggct
     7261 tttttgtacc tactaaaagc tctaaaatgc tctttttact caataatttt aagctcattg
     7321 gtcctgttat caaaaataaa atcataaatg atacaatagt caatagcatt gcttttactg
     7381 gaaaataaaa ttcagttaaa ttcatataaa acagtttgct taaatacaat aaaaacaatt
     7441 ttgaaattga taaaccaagt aatattccta acatcactgc taaaaatcct attatcaaat
     7501 tttcaattaa tatcaatttt ttcagttgtc tgttactcat tccaattatc atcaatactc
     7561 caaaatcttt caatctatat tttaagaaat ttcctaaaga gtacaatata aaaagtagac
     7621 taaaaccgaa tattattaat tctgaagtca taagagccat aaatgcagta gaaccactct
     7681 gcattccaga ttttgttata attggatgga acatagacac tgcaaaaaca aaaaatatca
     7741 ttatagaaaa aacagaactt aaaaaatatg ctaaatatgc cctgaaattt ctaactatat
     7801 tattataagc aaactttcta aaatccacta tcttacacct cctatttgag acaaaacagc
     7861 tagtatatca gaatagaaag aattactgct ttcagatttt tttatttctg tatatataca
     7921 accatctttt ataaaaatta ctctatctga ataacttgca ctatatgctt catgagttac
     7981 cataagtgtt gttacctttt gttctttgtt tatcctagta aataatttca aaacatcatc
     8041 agtagatttt gaatcaagat ttccagttgg ctcatctgca agaagtatgg caggtttatt
     8101 tataatagct ctagcaatag cacacctttg agcttgacct cctgaaattt cataggtttt
     8161 tctatctaaa attttatcta ttcctaaaaa tttagatata cttttagttt gtatattcat
     8221 atctttgata ctttccccct ctagtgtaag tggcaacata atattttcgc caacagttaa
     8281 agtgtcaatc aaattaaaat cctgaaatac aaaaccaagt tgtttccttc taaattcagc
     8341 aagtttttct cctttcaatt tacttacatc atatccatct aatacaacct caccttcact
     8401 ctgtctatca actgtagata ttatatttaa aagagtagat ttaccacttc cagatggtcc
     8461 cataacagac acaaattctc ccttttctat atttagacta accttatcta atgctttaaa
     8521 tggaatattt ccgcaatatg tttttgatat atttctaata ctcaatatgt tcattttata
     8581 ttctccataa ttttttattt ttactacaat accataatat cgtgaatata ctactttaac
     8641 cataaaaata ccctaacaat taacttacat atttgtaagt aagttgttag ggtatcttat
     8701 agtctaataa ttattaatga ttaatcaaat ttaaagttta agtgtttttc aaattcatct
     8761 aataccatag gtttagcaaa taagtatcct tgaaccttat cacaacctat ctctttcaag
     8821 aactctactt gttcataagt ttctacgccc tcacagatta ctttaatatc aatcgctttt
     8881 gccatttcca caatcttaga aataataatt tttccacgtt ttgtatctgt tgtttcgatt
     8941 aaaaatcctc tatctaattt taaaatatca aaagaaaggt cttttaacag atttaaagat
     9001 gaatatcccg aaccaaaatc atccattgat ataaggaatc ctatctcttt aatctttttc
     9061 attatatcaa tcaatatatt taaattatca aacacaacac tttctgttag ttcaagctca
     9121 ataaactcag gagatatatt gtatttactt atcaaatcag ttatattttc tataaaatta
     9181 tccctatata aatgaactct agacatattt acagagattg gtacaggagt atacccttta
     9241 tttatccact tgtttaatgt tttgcatact tcttcaaaca cgaacatatc aatatttaca
     9301 ataaaaccat tcttttcaaa taaaggtaca aaatctatag gtgaaataaa cccaaattct
     9361 ggactattcc atcttatcaa ggcttctgct ccttcaattt catttacatc atctaaacta
     9421 tacttaggtt gataatatac tataaattca cctttttcta aagctttatt catattatct
     9481 tccaatcgtt tttccttgta caatcgattt cttgtatctt cattaaaaaa tgaatatgaa
     9541 tgttcatatt tttccttttt actttttgct gcaatatttg ctctatcaat taacaagtca
     9601 atctttttaa tatcatcctt tttagtaatc ttatatattc cacttgacat aacaatttta
     9661 tacttagatg agttagtagt atttaagtta caaatttctt tatttatttt agataatcta
     9721 tttaaaagtt catcttcagt gttacaagca atcaacaata taaaatggtc attatccatc
     9781 ctagcacaaa tttcatattt atttgtatta ttatttaaaa cttgtgatat atgaattaat
     9841 atcttattcc cttcagcata tccaaacatc tcatttatat atttaaattt attgacatcc
     9901 aattgtacta agtaaaaatt atcttgataa taattcttta aaatatacat agaatctttt
     9961 ctaaactttt ctttattttt tattccactt aaagaatcat aataagccaa ttttttaagt
    10021 tgttctatta atttagcatt acttaatttc cacaatatca taaatattac tatataaaaa
    10081 tacaacttta tcataaaatt aactattaga tttttaaagt tcttaaatat attacatttt
    10141 gatactaaag tccaattagt ccactttatg ttcgtatatt ttacattata taatctccaa
    10201 ttatcccaag ataaaaaatc accttgacat tttttattta tattttttaa gatttcactt
    10261 ttagtggttc ctataatatt cccttctaaa tcaagcatct tacttttatc atttacatat
    10321 tttttgtttg gatgagaaat aatagtataa tctttatcta tcattagaaa tttaatagaa
    10381 tcatcaaaat tgcttctact tattaaatta tttacatctt gaaaataaaa agaagcaaaa
    10441 atggtcccaa tcatctcatt attttttaca attggtacat atatgataaa tactttgtca
    10501 cctgttacat tactgacttc aatatctgaa actactactt gctttgtttt aattgctttc
    10561 tcaaaactag gcttatcttt tattgagtta acattttccc tatatgtact tgaagcattt
    10621 ccttttgtat ctgttatacc aatcataaaa agattatatt ccttttgata tggacttaat
    10681 aattttccct tttcaattag tgatgtttca ccattagaaa atctatcatc ttgactaaga
    10741 gcttttaata aagatatgtt tacttctaaa tagttttcaa gttctctttt tgatgcctca
    10801 atcatatttc tagaagtaat ttccatagag ttacttgcat atatgatggt acttgttaaa
    10861 tcaatcaaaa ctaatagtat taataagatt aatatatgct taaaaactag cccatcaaat
    10921 actttttctc tttttttcat attaaaatac cattaattac acaatttatt tttctattat
    10981 ttaatgttag atttgacaaa tctgatttta ttagccacac attattcact ccttacaaga
    11041 cctttattgt ataactattt tatcatagtt agacaaagtt atgttactta gtatcaaata
    11101 ttacaataat aactgataaa ttattaaacc atctaaaaaa gtggctacat caaaatagag
    11161 attgtactaa gacctaaaag ttagactttc tacaggaatg aaattttcat tgttgaaatg
    11221 attaaaacat atttgatttt gtacaaaaag agtgcctcat gaactaaaaa gttcattttg
    11281 agacaccctc tctttaattt acaaattaag cattaacttt tgcttttaaa tattcatcta
    11341 ttgatgctgc tgctgtttta ccagcaccca ttgcagatat tactgttgct gctccagtaa
    11401 cagcatctcc acctgcaaat acaccctctt tagaagtctg accattttca tctgttatta
    11461 agcatctctt cttatttata tcaagactct ttgttgtaga agatattagt ggatttgggc
    11521 ttgttccaag tgacattata actgtgtcta catcaagtac aaattcagaa ccttctattt
    11581 ctataggtct tcttcttcca gaatcatctg gctctcctaa ttccattctt atacaaacca
    11641 tacctttaac atatccattt tcatctacta aaatttcctt aggatttgtt aatgtattaa
    11701 atataatgcc ttcttctttt gcatgatgaa cttcttcagc tcttgctgga agctcttttt
    11761 cacttcttct ataaactata tatgattctg aacctaatct taatgcagtt ctagcagcgt
    11821 ccatagcaac atttccacca cctactacag caactttttt accagaacta ataggtgtat
    11881 cataatcatc tctataagcc ttcattaagt ttactctagt taaaaactca tttgcagaaa
    11941 atactccatt tgcattttcc cctggtatat tcataaacat tggaagacca gctcctgaac
    12001 ctatgaatat agcttcaaat ccttcatctt ctataagttc atctactgta attgttttac
    12061 caacaattac attagtttct atttttacac ctaattttct tatattgtct atttcaggtt
    12121 gaacaacagc ttgttttgga agtctaaact caggtattcc gtaagttaaa actccacctg
    12181 gctcatgcat tgcttcaaag attgttacat catagccttt tttagctaaa tcaccagcac
    12241 aagctagacc tgctggacca cttcctatta ctgctacttt ttgatttttc ttaggctctg
    12301 tatcagataa atttatgtca ttttcttttg accaatctgc tacaaatctt tctaatttac
    12361 ctattgatac agcatctgat tttattccaa gtatacatac accttcacat tgactttctt
    12421 gtgggcatac tctaccacaa acagctggta atgaactgct cttagctatt actttagcag
    12481 caccttctat atcatcttct ttaatttttg ttataaaccc tggtatgtcg attcctactg
    12541 gacatccacc cacacatttt ggttttttac aagccaaaca tctattagct tctgccatag
    12601 cttcttcttt attataccct aagcatacct catcaaaatt tgttgctctc acagcaggtt
    12661 cttgttctct aactggtact tttacttttt tagcatccat tatttgttac ctccacatcc
    12721 acaattacta tgatgatgac tatcgccttc ttcaagtttt agcatagctc ttccctcttg
    12781 agtcttgtac atagactgtc ttctcattgc ttgatcaaaa tcaactaaat gaccatcaaa
    12841 ttcaggacca tctacacatg caaacttagt ttcatttcca acactaactc tacagccacc
    12901 acacatacct gttccatcta tcattattgt atttaaactt actatagtag gtatatttag
    12961 ttctttagtt aattggcaca taaatttcat cattatcatt ggtccaatta ctattgcttg
    13021 gtcgtatttt ttaccttgat tatcaactaa atcttttaat aggtctgtaa ctcttccatt
    13081 aaatccatat gtaccatcat ctgttgatac atatacattt ttagctactt ttttcatatc
    13141 atcttctaat ataattaatt ctttagttct tgcaccaatt attacatcta catctaatcc
    13201 atgctcttta aaccatttaa cttgtggata aactggagca gaaccaactc caccagctac
    13261 aaataatatc tttttatttc ttaattcttc tatatcttca tgtataaatt cacttgcttg
    13321 tcctaatggc cctacaaaat ccattacaaa atcgttttct tcaaacattg ctaacttttt
    13381 agttgaagca ccaactgttt ggaatacaat agttactgtt cctttttctc tatcatagtc
    13441 agctattgta agaggaatcc tctctccttt ttcatcattt ttaattatta taaattgacc
    13501 tggttgagaa gattttgcaa ctctaggtgc ctctatttcc attaaataaa tactatctgt
    13561 taattgtctc ttactaacta ttttattact catctcgcta ttctccattc taacaaatat
    13621 atttttccca ctttaaattt aattaaaaac ataaacacac aaaactataa ctctttataa
    13681 tataatatta gttcttggtt gattgttttg tattggacat cccccctata ataattataa
    13741 ctgcccaaac tacaaatagt tgatattaac aaatttcttg taaatgccaa taaacactaa
    13801 gtctatatca tacgtctaat ttgttataga tttaacctaa tacacactta aagtatacta
    13861 tattatgcca aatttgtaac aaaaatttta taaatacata ataaaatttt tttattcaat
    13921 tatttattta ataaattaac ttaggttttc ataataacac taatttcttt aaaaactaaa
    13981 cgtgtataag gctttaatct attgcaatac cagctttcat attgtataaa atatactctt
    14041 attttattat atatctaaaa ttttcaatat tcattaatta tttgaatttt tatataaaat
    14101 ttttacaatt tctaaagatt tatttactta tgtaataaat tataataata ttagtttata
    14161 aagttaataa ttaatataaa ttaaaataaa gataatataa acacaggagg tacattcttt
    14221 gaaaaacatt atttcagcaa aagaacttat atcaaaacta gaaaaaaatg ataatctagt
    14281 tgtaatagat tgcagatttg atcttatcaa tagaacttat ggtattgatt cttataaaaa
    14341 aggacacatc aaaggcagtt ttatcttaga tatagacaag gatttatcat ctcctacaaa
    14401 agaacatggt ggtaaaaatc ctttacaaga ccctttaata ctaaaagaaa aattagaaaa
    14461 aatgggtgtt gataatgaca ctacgattgt aacttatgat gatggagatt taaatggagc
    14521 ttgcagatta tttttccaat taaaacattt ggggcttaaa aatgtctatg tactagatgg
    14581 gggaataaca tctttcgtaa aggaaggtgg agaattggaa gagaaagtga atataccaag
    14641 ttgtacaggt aaggaaatta gaccaaatat aaacaatggt ttagttgttc caatggaata
    14701 tgttaagtct aaattataca aaaaagatac tgtaataata gattgccgtg ctaatgagag
    14761 ataccaaggt ttagttgaac ctgcttactc aaaagctggt catataccaa gtgcaaaaaa
    14821 ttatttttgt aaggatttaa taaaaagtga ctttgaaaat ggctcactta aagatataga
    14881 atttttaaaa aaattcttta aagatttaaa taattatgat gaagtaattt tatcttgtgg
    14941 ttcagggata tctgcttgtg ttaacagtct tgctcttaga gaactggata tacctcacaa
    15001 gatttatatt ggtagcttta gcgactggat tagttatgat gacaatgaaa tcaaaactgg
    15061 tcaagaataa ggctcataat ctatataaaa tcagcatatg atagcttaaa ttttgtaaag
    15121 gcgtcagtca ttgtagactt tcgcctttac ttattatttc atatactctt taaatttatt
    15181 atatatattt tagttgataa tattaataaa ctgcaatatg accatcacat cttgattccg
    15241 tcccacaaat ataactttcc tgttctgttt taaatattat ttgacctcgt cccatgtcaa
    15301 cagtatcatg aattactttt atttcatgac ccttttcaat taatgaatct attatatgct
    15361 ttggcatctc tggttcaact tctatttctt ttccttttat ccactgccat cttggagcat
    15421 ctagcgcctc ttgtggattt aatccaaaat caatcatatt tgttaacacc tgaatatgtc
    15481 cttgtggttg cataaaagct cccattacac caaatggacc tattgcttta tcttctttac
    15541 ctaaaaatcc aggtattata gtatgataag gttttttaaa tggttttact acattgtggt
    15601 gtttagggtc taaattaaaa ttatttcctc tactatgtaa agcaatccca gttcttggta
    15661 tcacaattcc tgaaccaaaa tttatgtaat tgctctgtat atatgaaacc atatttccat
    15721 ccttatctgc agtacaaagg tatactgtac caccacaata tggctctcct gcagttggat
    15781 acaaagcctc tttattgtca attaataaac ttcttttttt ggcatactct tggcttagta
    15841 attcctgaat ctttaccttc atatgctcta tatcagttac atatgtttta gaatctgcaa
    15901 aagctaattt taaactctct ataattttat gtatgtcttc tacattttct atatttcctt
    15961 ctaattccaa ttcttttaat atgttaagtg ccattaaaac tgttattcca tgaccatttg
    16021 gtgggatttc aaatatttta tatcccttat attctgtact tataggttct acccatgttg
    16081 gataaaaaca ctctaagtca ctctttctta tagccccatt aaatttttta gaatattcat
    16141 ctattttatc agcaagtctt cctctataaa agctttcagc ctgagtattt gctatctctt
    16201 ctaatgtact tgcctgttct tcacatataa atatatctcc agcctctgga gctttaccat
    16261 ctttagaaaa tgtatcaaac catggtttga actcttctcc aataagttct ttttcataga
    16321 gttcatatga ttttttccat accttagcta cattaggaga tactacgtat ccctctcttg
    16381 catagtttat cgctggagat aagcattcca ttaagctaag tttaccatat tttttattta
    16441 attctgacca agctgcgggt attccaggta cagttactga tccaaaccca tattttggca
    16501 tttctttcat attattataa ttttttaatt ccatattttc tggagcaaag ccactagaat
    16561 ttaaaccata caatcgtttt tcttcctcta tccaaacaag ggcatatgca tctcctccaa
    16621 tcccattgct tgtaggttct actactgcta atgtggcggc tgttgcaact gctgcatcaa
    16681 cagcatttcc accctttttt agtatttcaa gtccagcttg agatgctaat ggtgttgatg
    16741 ttgcaactgc tccattttta gcatacacga catttcttat tgatgagtat ttatgttggt
    16801 aggcattaaa cttcataaat ttcagctcct cgtcattttt tatttgatat tctgcttaga
    16861 tttattatat aacatcaagt aatgtaactg atacaaaatg atataaaata tagacttttt
    16921 cctaacttta attttatctt taaataaata tcttaaactc aattctagta ttttctatct
    16981 gcacttaaat aagttatttt attcaaaaca tatatctaat tcttttgact taaaaataat
    17041 ttattctttt atcatgttta gagcatattt taaagttaaa aaataatata taaaatatcc
    17101 tataaaataa atgactagag ttatgataat tggtacaagt aatgaccttg gtataaactt
    17161 ttgtgctata gacatagcaa ataaattatg aactgtacct acaactaatg gcattaaaaa
    17221 tataactttt aactgttttg atattatttt ctcaatatct ttattatttg ctccaagttt
    17281 tattaacata atatatcttt ccttatcatc atatatattt gataattgtt taaataagat
    17341 tatactacct gtacataaaa gaaatactac agacaaaaat atgcctataa acagcattag
    17401 accacttaat tttatcaagt tattataact ttcaatactt gatgtaaaat taaaaggata
    17461 agtaaatttc atattttcac ttactatatt ttttaatttt aaagtcaaat ccagttcttt
    17521 tttttcattt tttatatcaa ttaatcttat taatctagaa tttccatgta attttaactg
    17581 attaaatacg tcatctttta ctacaattaa atcaaacgta gcttgtgaat ttatttctgg
    17641 ctccaagatg cttttttgta ctttaaacag atttatatca tactcatttg tatctttaat
    17701 atgcaagttt attttttcaa tctcaaagtc tttaaaaaat atttttttgt atgaatcaga
    17761 aacatagtac acagattcct ttgaagttaa ttcttcataa ttgttattct gatattgtct
    17821 taatttttta aaatcacttt ctctaataat atctacagac gttctatctt ctatataact
    17881 atttccattt ttataataca tttcaatatt tatatctttg tctataagtt ctattgtttt
    17941 atcaaagatt atcttattat cttttttata tttatataat aatttgtcaa tttcgttatt
    18001 tacataagaa tttcctaaat ttatggtata actgtattta taattttcac ttatgttcct
    18061 atctatatcg taataaagtg atatggtaaa ccctagcata gttacacttg tagctattaa
    18121 tattgctatt acagccaata cactactatt gctctttaat ttaaatccaa gttcagaaaa
    18181 tgcaattaaa ttctgtccct tataataaaa actttttctc ttcttaacag catcaataat
    18241 catatacata gttgatgaaa aaaataaaaa agttccaggt attattgtaa ctaatataaa
    18301 aactgaaagc ataatatttt cagcaataaa ataactaatt gacattaaat aagaaatagt
    18361 tattaataaa acaccaagta cacattttaa ctttataaat tttttaaact tatacttttc
    18421 tggatattta ttaaataact ctataattct cttatttctg ataactatag tatttcttat
    18481 tccaataact ataaatatta ttaaaaatac agctaatgtc tgaactaagg cctttatact
    18541 taagttcata tttactacta tcatttcatt cattaatttt acaagcatca tagtcataag
    18601 ctttgaaaat aacaatccta aaaatatacc tattaatatt gcaactatac ccatcaaaaa
    18661 agtttcatat aaaaatattt ttcctatctg atttttcctc attccaagta aactataagt
    18721 tcctacttct cgcctacgtc tattgaaaaa aaatgagttt gaataatata taaataaaaa
    18781 tacaaatacc actattacaa ttgaacttgt attaatactc atcctagttt tctctccaag
    18841 tgaactcaac gcttcattat actctataga tttaaaacta aaaaatacaa atacactaaa
    18901 tacaattgaa ataaagtaca ttaaataatt aaaaaaacta ttctttacat tttgcattgc
    18961 aattctaaat aaagtcattt ttattaactc ctccaattaa ggaaactgta tttactattt
    19021 tattatagaa ctctctgtta ctttctccct ttacaatttc tgtgaatatt attccatcct
    19081 ttataaagag tattctattg caaaaactcg cacttatagc atcatgagtt accatcaata
    19141 ttgttttatt gctgtctttg tttaatttta atagacaatt caacaaatcc ctagcagatt
    19201 tagaatctaa tgctcctgta ggctcatctg caagtactaa tgatggtttt gttgctatag
    19261 ctctacatac agctcctctt tgcttttgtc caccagaaac ttcgccaggg tatttatcta
    19321 atatagattc tatatttaat tcttttgaaa tctcttttat tctattttct attactgata
    19381 ctctttcatt ttttaaagaa agaggcaaca ttatattttc ttttattgta agtgtatcca
    19441 aaagattaga atcttgaaat acaaagccta gattatcacg tctaaaatct gccaattcat
    19501 tttgcttcat tttaatagta ttctttccat ttatataaat atctcctgat gaaggtaaat
    19561 ctattgtaga aataatattt aaaagtgttg atttaccagc accggaagac cccataatac
    19621 caacaaattc tcctttataa accttgaaag ttattcctct tagagcttca tgttttgaac
    19681 cttttcttcc atactccttt tttatatttt caacatataa tatttcttcc atagttaata
    19741 atcacctttc atcacaatta gttatttatc aattctcaca aatatattat atatattaaa
    19801 atggctttta aacatttaat tatattaatt taaggttaca ttttcgtaag tattaattat
    19861 atttcttcaa atttattgca attatgttta aaatataatt tatcaagtaa aatatagtta
    19921 tattaatata attattttag gtaataaggt agaaatattt taatttatca agtagaatat
    19981 agttatgtta atataactat tttgaattag gaggtaagaa tgtttaaaat aatggtagtt
    20041 gaagatgacg tctcattgaa aaatatcata gcaaagtgtc ttactaaatg gggacatgat
    20101 gttcatcaaa tagaaaatct tgaaaatata atagaagagt tcaaaaacta taacccagaa
    20161 ttagttttat tggacataaa ccttccattt tatgatggtt ttcattggtg taatgaaata
    20221 agaaaaattt caaaagttcc tataattttt atttcttcaa gaaattctaa tatggatgta
    20281 ataatgggtg taaatttagg tgcagatgat tatatacaaa aacctttttc tgtagatgtc
    20341 ttagtagcta aagttaatgc ccttttaaga agaacttata attttgttga taataactca
    20401 aatcagatta ttcacaatgg tgttacttta gatttatcaa ctgcaacaat aaactatgaa
    20461 gataatacta ttgagctaac aaaaaatgaa atcaaaattc tccatgagct tatgaaatat
    20521 aaggggcaga tagtaagtag gaataaactc atgaaaaaat tatgggataa tgattggttt
    20581 gtagatgata atacattaac tgtcaatgta aatagaatac gctcaaaatt aaatgaaatt
    20641 ggtttagaag attttataga aacaaaaaga ggattgggtt atataatcag ttaaaacaat
    20701 tctaagtagg tgaatttatg agctttaaag attttctcaa ggataaacta ggttttttag
    20761 tatacaattt tactttctta atttttacag tatcagttat tatattttct cctgtagatg
    20821 tttttctgac tgatactatt ttatatatat tagttgtaaa tgttgtgttt ttatttttat
    20881 atctatttat tagctacatc aagaagaaca aatttttaga taagataaaa aatgatacat
    20941 tcaaaattaa tatgaatgat atagaattag ctagatgtaa aaatgaagaa aaaatatact
    21001 tgaacattat taaaaatcat caatatcaat gcaataacat aataaataat aatatcgaga
    21061 aatttgaaga aaacaaagag attttaaata tgtgggtaca tgatgtaaag atacctatag
    21121 ctataataaa actcattctt gaacaaaatg aaaatttaat tgatgaaaaa atttcagatg
    21181 acatagatag tgaaatattt agaattgaaa actccgttga aaaaatttta tatttatcaa
    21241 gactcgaaga ttttcataag gattttttaa ttcaagaggt aaatattgaa aaaatcatta
    21301 gaaatattat aaaaaaatac tcaaaatatt ttatttcaaa aaaaattatt ttagacttaa
    21361 ataatttgaa ttttaaggtt ttatctgatg aaaaatggct atacttcata ttcgagcaat
    21421 tattgagtaa ttccctaaaa tactcctcat taggagataa tatatctatc tattgcaaaa
    21481 gaaccaaaaa ttatttacaa ttaagagtgg aagatactgg ttgtggtata aaaaaggaag
    21541 atttaaatcg aatattcaat aagggattta caggtaataa tggaagaaac aattctaaat
    21601 ctacaggtct tgggctttat ttagtaaaag aactttgtga taagcttggt cataaaattg
    21661 atgtagattc agagtacaac caatatacaa aatttactat tacattcaaa tgtgatttat
    21721 agtatcttat tattgatagt ttattttcat taacttatat tcaacttctt atagtaattc
    21781 tatatgtaca tcccagtata taattaagta gtttttataa aaaggaggaa gacatgtctt
    21841 ttctaaaaaa atttaaaaat aaaagattta gaaataacag ttttaaaagt aacaacttta
    21901 gaaatagcag ttttggaagt agtggcttca agtctaaaaa taaaggtttt aaaaacaatc
    21961 cctttaaaaa taagagattc aaaatatatg caggaatagc agtaatcata cttttaattc
    22021 taggagttct tgcttatgtt gattcgaaaa acactgaatt acaagctaat gaaaatttta
    22081 tcgaaacata tactattcct gaaaatgaaa aaatatttat aaatgggatg gttgttccta
    22141 agcaaactaa ggacttcaat atatctggag attatgagtt aagtgatgtt aatgttacaa
    22201 atggtcaaaa agtaaatcaa ggagaccttc tttttactgc taaaaatcca actataatag
    22261 cagaaataga tagtttaaaa tcacaactta gtcaatacaa aaaacaaaaa atatcacttt
    22321 ctgatattgc tgaaaataaa gatgctattg cttctataaa tgcacagata actgctttaa
    22381 actctcagat agcttctctg gataaaaaag cttatgacag agttactgct ccttttgatg
    22441 gcacagtata cttgaatgac caaactggaa atccagacca accagtttca tttatgacta
    22501 ttcaaggtct agagttttat atgaaaggac aagcaagtga acaagattta cctaaaatga
    22561 agattgacca aatggtcaat atactcgttt tttcaactga ccaaaagctt actggtagaa
    22621 taagttttat atctgataaa ccatctactc caaatactga aatgggagct cagcagaata
    22681 cactatctta ttatgatata aacatagcat ttgataatca agaaggatta gtaaatggat
    22741 tccatcttca agcatcactt gaagtagcta attcaagctt taaaatacca gcatcttgtg
    22801 tacttaaaga caacaaacac tcatatgtat ttaaggattt agatggtata ttgaaaaagc
    22861 aaattgtaga tgtagcaagt caaaatgatg attttgctgt agttagaggc ggtcttgaac
    22921 aaggcgatat aataataaaa caccctacta aagaaatgaa agaaggagac ccagttcaag
    22981 gcgatggcgt aactgctggt tctaataatg gagatactac tccaaacaaa aaagtagaag
    23041 aagttactat ggatgtgaat taatttacat atgttaatta aattagaaaa tattcaaaaa
    23101 tattacaaag tagggaaaga tgaattacat gttttaaaat ccttaaattt agaaattgaa
    23161 tctggagaat ttgtcatgat aatgggtaag tctggtagtg gtaaaactac tttacttaat
    23221 atcttaggtt ttctagatgt atttgatgaa ggaagatata tatttgatgg aacagatgta
    23281 actaatttga gtgaaaatga acgttctgtt tttagaaata ttaatattgg atttgttttc
    23341 caacaattta atttaataga aactctaaat gtatatcaaa atgtagagtt gcctctaatt
    23401 tacaataaag cactaaaaaa atctaataga gaagaaattg ttaaagataa attaagttct
    23461 gttgggcttt tggacaagct taagcagaaa ccacttcaat tatctggtgg tcaacaacag
    23521 cgtgtagcca ttgcacgttg cctagcaaat gaccctcaga taatctttgc tgacgaaccg
    23581 actggggcat tagatagtga aactagcaga gaaattatgg agcttttaac aaggctcaac
    23641 aaacaaggta agactataat aatggttaca catgatcaag atttaactaa gtatgcaact
    23701 aaggttatac gacttaaaga tggtgtgttt acttcggagg tgtaatcatg agtttattaa
    23761 aaaattcttt ggccaattta aaaggtcaca agcttcgtgt atttgtagct ttactctgga
    23821 ttataatagg aataacttca gtaatacttg ttagttctat aggtaatgga tttcaaaaag
    23881 aaattaagaa gtctgtaaac aatgtaaacc ctaataaaac tactatttcg tttgaatcag
    23941 ccgataacac aggtcttact gatgatatga gtattttttt aaaacccttt aatgcaaaag
    24001 atttagaaga attatcattt gttgaaggag tagaaagaat agctccttca agagatgggt
    24061 ttaaccttga ttcagtttac tcttcacaag catcttttga taaaaaaact acgtatgttg
    24121 atgttggacc agtaaaaaaa gattctaaaa taaatttaat ttgtggtaga gatttttctt
    24181 tagatgatga aaaaagaaaa gtaattttac ttacattaca aagtacaagt gaaatttttg
    24241 aaaatccaga agatgcctta ggtcatggta tcaacataaa tggaactata tttgaaataa
    24301 taggggtatt agatgattct cagcaaaacc aagctggagg attctttgga ggttaccaag
    24361 atatgcaatt tactacttcc ctagtaccta aaaaggcttt tgacacttta atgagtcaaa
    24421 attcttattc aaatgaaatt taccagttag acttagtttc ttctaaaggc tataatgtaa
    24481 atgaagttgc aaacaatgtt atagctaaat tatatgagat gcaccctggt atcaatggtt
    24541 cttatactac accagaccca actgaacaga cagcttatct tgaaagcatt aattccaatg
    24601 taaacaaata tgtatctata ataactgtag ttgcaatgtt tgttggtggt attggtgtaa
    24661 tgaatataat gtatgtatct gttatggaaa gacaaagaga aattggtata agacgtgcta
    24721 ttggagcaaa acctaggtct atattatttc aatttttagt tgaagctgtt tttataacag
    24781 tatgtggtgg aattttagga actatagttg gatttactgc tactaactat gtttctaaat
    24841 atataggttt tgaagctata cctagcttaa atagcttatt ttatgcaatt gtagctacta
    24901 tattgactgg agttgtattt ggtctgattc cagcctttaa agcctctaaa ctagacccta
    24961 taaaggcaat ttataagtag aaattgtata aagattttcg atttttagat tagtttatat
    25021 aaaacatact taaatatata acgcactatt atatatgata gattaggaac ttaatctttc
    25081 caaatataat agtgcgttct ttcataaaaa ggattctctt ccttactata tctaaattac
    25141 caaaatgtta tgttctaatt gttcaaacta atacttccaa ttttgattaa tcaatctcat
    25201 tctgctaata tacaatcttt tactttcaat cattgtacac tccgccttaa aaaaataatc
    25261 ttaaattagg cgttatatac aatctcccca ttacatattg tataattaac ctttccatat
    25321 aaagatttac ctttaaacgg tgaattatca gctttagaaa caaagctttc aactgtccat
    25381 tcttcttctg gattgaatat aacaatgtct gctacagccc cttcttctat aaatccaata
    25441 tttaaattgt acaactttgc aggatttata gacatttttt ctattaactg catcatacta
    25501 agatgatttt tatgcaccaa atttgttatt ccaagagcta aagaagtttc aagcccaata
    25561 attccacttg gagcttttat aaactctcta tctttttctt ctttactatg aggtgcatgg
    25621 tctgttgcta ttatttcaat agtaccatca tttaatccct ctataatctt atctctgtcc
    25681 catttacttc ttagaggtgg attcattttt gcatttgttc caaactccaa tacatcttcc
    25741 tcagtcaatg taaagtgatg tggtgaagct tctgcaacta catttgcacc taagtatttt
    25801 gcaaatctaa ccatatcaac agatacacct gaacttatat gttgtatatc aactttagca
    25861 ccagtcttta gtgccaacat acaatctctg gctaccataa catcttctgc tacacttgat
    25921 gcacctttta atcctagttt tgaggctacc tttcctgcat ttacacctgg atttccaact
    25981 aaagaagggt cttcttcatg aaaactaagt ggtacatcca actcttttgc cttaatcatt
    26041 gcctccataa ttagattgct atccattaaa ggtaatccat catcagtaaa ccctggtaca
    26101 ccagcttttt taagagcttc catatcaact aactctttac cttcaaaacc tttagttata
    26161 gctgctgctt gtaaaacatt tatacatgca ttttttgact tttctttaac ataattaaaa
    26221 gtatcttcat tatctacaat aggattagta tttgccatac atataacagt tgtaaatcca
    26281 cctctagcag cagatttagc tccactttct atatcttctt tatatgtaaa cccagggtct
    26341 ctaaagtgta catgtacatc cactaaacct ggagcaacta cattaccact agcatctatt
    26401 attttttcat attcatcact ttcatcaaac ttgcctattt tataaatttt attttctttt
    26461 ataattaagt caatattctc atctctttga cttttagggt ctattactct accattttta
    26521 attaaaatca tattatttct cctttatatt tttaatttat atagactcat ataatattat
    26581 acattatttt acatacttaa atacaaaatt acgtttgaca tcaatagcct ttttaggaca
    26641 aagttcatgg caacagtaac atcttataca tttacttaag tctataatag cacccttagt
    26701 ccctatctct atagtggatg caggacaagc ttccttgcat tttccacatt ttatgcaatc
    26761 ttgaaatctt accacaggct ttggtgttat aagctttgaa ataggttcat ttaaaaattt
    26821 tggtagcttt acggaaaaca atcttaaatc tttacttaca tttggaatct tgtaattttt
    26881 tataattaaa tcttttatat cttcacctaa aatttcaata tctgaaaaat cttcttgtat
    26941 atatcctctc ttaatagcac ctctaattgt agcaactcta tttggaagta aacttataat
    27001 cttacatgca acaacatcta tagcatatgg attttgtgat gctaatgaaa ctcctatttc
    27061 tcgagtagta ccagctgaag gtccatcacc ttccatacct actataccat ccataattgt
    27121 caatgttggt tttatataat cacaaatatc taaaagtaca ttttcgcaaa acaactcttc
    27181 tgtaggaaat ctataatgta tctctgcttt tttcaatcca gctatgcatc catataagtt
    27241 ttttgtaccc ccagtaaaag ttgccattat atgagtcttt aatttacaaa gatttattat
    27301 ataatctgaa tctactattg gtttaataat atccatatat tttagaacat gtgctttttc
    27361 actatgtatc ttaacatctg aaacatcata atttaactta atgcccagtt catttgctac
    27421 ttcttcaatt ccagatgcct tataaatgct cttaagagaa ctttgattat atggaccacc
    27481 agggctatct gctattgtaa tatcacaatt taactctaaa agtttttcac atacaacttt
    27541 tacaaccata ggatgtgtag ttgtagcttc ttcaggcttt tttttcatca ataaatttgg
    27601 ttttataagt actttgcttc cttttttaac aaacttatct ataccaccaa tatcctctaa
    27661 atttttttca atagataact ttacttcttc ataattgtaa gttttacaac tcctaacaga
    27721 taccgacttc atattatctc catccttcta tcacaacagt ttatttatat aatttaaaaa
    27781 aggagaaacc aaagtttctc cttttaatct atgttttaat tgttttaatt attattttcc
    27841 aaaatgtctg tttaataatc ctaagaatgc tttaccatgt ctagcttcgt ctttacacat
    27901 ttcatgtact gtatcatgta tagcatctaa tcctaattct ttagctctct tagctaattt
    27961 taattttcca tcagttgcac catactcagc atcaactcta actcttaagt tttcttttgt
    28021 atctgcaact acaacttctc caagaagttc tgcaaattta gcagcatgtt cagcctcttc
    28081 aaaagctatt ctcttatacg cttcagctac ttctggataa ccttctctat cagcttgtct
    28141 actcattgct aaatacattc ctacttctgt acactcacca gtaaagttag ctcttaatcc
    28201 ttcgattatt tctgcatcta caccttgagc tactcctatt ctatgttcat cagcccaaac
    28261 catttcgcct ttcatttctt caaatttatc agctccaact ttacatactg gacattgtgc
    28321 tggtgcagca tctccttcat gtatatatcc acatactgta caaacaaatt ttttcataat
    28381 taatttcctc ccaattttat ataattaaat ttttattttt aagtttaata acttgctaca
    28441 agaatatata taccccagac tttatagctt aaacactaaa aataaaattt atttcctaat
    28501 taattttatc actttgaaac accagtatca accaagtttt gatgtcaaat ttctacataa
    28561 tacataattt atttgattaa ttaggaaata gttgtcatat taaatacttt ctaatgaaga
    28621 ctcctctgaa tctttaagtt tcactttttt gctctttaaa aaagataatt tagtttctgc
    28681 agttatgatt gcaacaaata tcaagatact accaataacc aattttgctg taataagctc
    28741 ctttaaaatt attatagaaa atattgtacc aaatacagcc tctgtggata atattatagc
    28801 tgttctagtt ccatcaactc ttttttgaca tatagtctga aataaaaatc caattgtagt
    28861 actaaataca gctagataca tagttcccat gtaaccagat aattcagctt ccatctttaa
    28921 ttgacctgca aatgtttgaa ctacaacaga cattaaaaac gctactgtaa attgaatagc
    28981 tgtcaatgcc attgggttgt tatcttttgc aaactcactt gtaaagaata tatgaaatgc
    29041 aaatccgaat gaacatataa gtgttagaaa atctccaaaa ttaatagaga aatcagcttc
    29101 taaagaaagt atcccaattc ctataagagc taccaaacta cttattattc ctattttatc
    29161 aagttttctt ctataaagta taaatcctat gaacggaact attacaacat tagctgctgt
    29221 tataaacgca tttttagatg gtgtagtgta cataagtcca atagtttgta ctgtgaatgc
    29281 tagaaataaa aatattccta aaatccctcc tgcttttaat aattttttac ccatattggc
    29341 acgaatctgt ttaaaaaaca gtaaattcat aattatagct gccaagaaaa atcttaaagt
    29401 tatgatttgt agaggtgtaa gcccaccgtc taatgcaaat tgggttgcta caaagccact
    29461 tccccatata attgctataa atattagtcc tatttctcca aagtattttt tcaataaagc
    29521 cccctccttt ttattttttt gcaaaattat aaacccccta aacagcaaga gagtttttct
    29581 ataagcatta ctataaatta atatagtaaa ttttttcagt attttaaatc taaatttaca
    29641 tacattttga gctcaaattt atatccacta tttaacagta atatattaat cattttttgt
    29701 aaacaccttt ttaataaatt tttatatttt ttatattttt ttacctatac taaatttttt
    29761 tatagatatt tttaatatat atgatacttt aatattatgc aaataatgtc atataagtta
    29821 cactttagtt atcttagtta caactttgtc ggtttacttt ttctactttc ttcgatataa
    29881 ttataatata tttttgatac aattcgacaa aagggggaat gctgtaatta tggtaaaaaa
    29941 aagaaaaaag aaaactgtta cacttactat acttgttgta atagttattg gtattttttc
    30001 tatggcatgg gcggacatgt ctagaaaaaa agaaatgaaa gaaactcaag aaagacttaa
    30061 agctgaaaga ttagaaaaag aaagaattga aaaagaaaaa aatgaaccta ttattggtgc
    30121 aaaaaaagaa gctgtaaaag aatatggata tgacgcaaaa atagtttggg acaaacttaa
    30181 caaatacgac tattcaaaca atggagaaaa gatagtcttt cttacatttg atgatggacc
    30241 atctactact aatactccac aagttctaga tatcttgaaa agacatggtg ttagaggaac
    30301 tttctttatt aagggtgatt ctcttgaaag aaaaggagct aatgaaattt taaaaagaac
    30361 atttgacgaa ggaaatgcaa tagcccatca ctcttatact catgactata aaaaactata
    30421 tcctaacaga agcctaaatc tcgatacatt cgtaaatgaa cttaacaaaa ctgatgaagc
    30481 tatgaaaaaa gtcttaggaa agaatttttc ctcaaatgta gttagatgcc caggcgggta
    30541 tatgtcatgg aaaaatatgg aacctctagg aaactactta aaagagaaaa acatggcatc
    30601 aattgattgg aacgctttaa atgctgatgc agaaggtaaa aagaaaaatg cacaagaatt
    30661 atttgaacat gcaaagaaat cttctgaagg caaagaaatg gttgttcttt taatgcatga
    30721 tacttatgga aaacaagaaa cagtaaatgc attggaccaa attataacat attttaaaga
    30781 caatggttat caatttaaaa ttttaatata ataaaaaagc aagtttattg aatgtacatt
    30841 ttatactcaa tagacttgct tttactttac tctattttac tagctcgatt tttacaaatt
    30901 ttttctttcc tatttgaaca actaattcac tctcttttac aatagtgctt aaatcctcta
    30961 ctttttcacc atttaccttt actccacctt gagaagctaa tcttctaact tcactcttac
    31021 tcttaacaat ctcattagaa actagtactt cgattaagtc aaatccatct tccttaactt
    31081 gaattgtttg tatatcttca ggtatttgac ctttttggaa tacagattta aatctttctt
    31141 cagcttcttt agcagattct tctccatggt ataatgttac tatttctctt gctaagttca
    31201 tctttatatc tcttggattt actgaaccct ctttcaactg agattctatt ttattaactt
    31261 catcaggatg aacatctgtc actaaattgt agtatttaat tataagttca tcaggaattt
    31321 ccatagattt ttggtacatt attcccgctt cttcatctat tccaatatag ttacctaaac
    31381 tcttactcat tttttcttta ccatctaatc cttctattaa aggcatcatt attactattt
    31441 gagactccat accaaattct ctttgtaatg atcttcccat tagtaaattg aatctttggt
    31501 cagttccacc aagttctata tcagcttcta atgctataga gtcatatgct tgcattaatg
    31561 ggtagaagaa ctcatgtact gatattggca tttgtccttc atatctcttt ttaaaatctt
    31621 ctctttctaa cattctcgca acagtaatag ttgctgctaa ttttattaca tcttcaaaat
    31681 ttaacttagc taaccactcg ctattaaatc ttacaatagt tttttcttta tctaaaactt
    31741 tgaaaatttg ttcttcataa gtttttgcat ttgcaagaac ttgctctgtt gttaaagctt
    31801 ttctagcttt agattttcca gttgggtctc caatttttcc tgtaaaatct ccaattatta
    31861 ttactatttg atgacctaaa tcttgtaatt gtttcatctt tctaagaact actgtatgcc
    31921 ctaaatgtat atctggagca cttgggtcta gacctaattt tactatcata ggctttcctt
    31981 ctttttctga tttaataagc ttttccctta actctttctc atctattaaa tcatctacac
    32041 ctttcataat tattcgcatt tgctcgtcta tcgatttcat ttttcattcc tcctaaaata
    32101 tttatataat ctataatttt tatttttata ataaaaaaag ctttcatcct cttaaaagga
    32161 cgaaagcatt gcttacgtgt taccacctta gttcatcaat atctcacgat attaatctct
    32221 tagagtacaa ttacatatac tcgtgtacta taacgtgtac taatccgata tctcttaatg
    32281 gttgttatct ttcagagata gtgctctgag atgtattcaa actaaatcaa tttattccat
    32341 ttcaccaaac tggaactctc tgttaaataa aatctagccc tacttcttct cttcatagca
    32401 tttatatatt cagattattt catcaattac aagaaatttt tcttaactta ctcataatat
    32461 attattattt ttatattttg tcaacctttt ttattattat atacatgttt ttttacatta
    32521 tactactttt ttatattttt taccaatacc caaaatttat ttttcaatca aaagatttat
    32581 ttgtttattg actatattac tctgactcaa tcttatattt attttcttat ttaaaaatgc
    32641 gtttataatt attaaactaa taactgttac atcaaatata aaaaacagca ataaaattat
    32701 tatcaaaaat aaaattctag catataataa ttttctaaac ttagctatta taaagttttg
    32761 tagtgacata catgagtctc taatgataaa atagacactt atataggtta ttgatataaa
    32821 gattgttttt aaataaacag aatcaacttt aacattcaac agttttagaa cttcaaaaat
    32881 ggctagataa gaaacacata tgtaaaaagc tttttttgag caacataaaa attggtttaa
    32941 atttctaaaa ttcttaaata ttaaaaattt ttttaaagaa ttagaatcta aaatatgcaa
    33001 tttattccct aaaattaaac ttaataaata tatgcaaaac accataccaa aaggaaacaa
    33061 tgctatcatt aaataataaa taaaatttgt atacccatta aaataaatcc atttgctata
    33121 tccttgaaat tctttcataa aactataacc tattaatgtt gaagcatata tatcaatgaa
    33181 aaccattaca ataaccccaa atactgaacc atatactaaa tcatccataa ccattgtagg
    33241 cttatttatt agatagccac acattatacc aagtaataca ctctgacttg cccaaatagc
    33301 agttcctaga tttccaagta ccagagaaat tattaaaagc gaagtaattc cagataaaat
    33361 ggtatacttt aaatcacatt tcaagcagat tatacaaaaa aatactggca ctataaaatc
    33421 taagtaaata gcatatccaa atccagtact cacagctata attgttacta ctatgaataa
    33481 agatgacaat aaagctgctt cagttaattt tttagtagta ttcaaaacac tgcctccata
    33541 aatcataaat tttctaacta aagttttgtt tttaatatag tatatcactt tttaaaaata
    33601 tttttaataa atataaattt taataaaggt atttatgtta aaaatggtat aatgtatctt
    33661 aatattcagt tttttaagat gctaggaggt aattactatg tttaaaatta aacactttaa
    33721 tgatttgagt ttagatgaat tttatgaaat agcaaaatca agatatgagg tatttgcttg
    33781 tgaacagaag atattttcat taaacgatta tgatgatata gataaaagct cttatcacat
    33841 atttttaaaa gaaaatggat tgatttgtgc ttacgctaga ataattccta aagaatacag
    33901 ctcttataat gatgtttcca ttggtagagt tttagttctt tctagtcata gaagaaaagg
    33961 attagcaaaa caaatgatgg attgtgctat agattttata aaagttaact tacacgaaaa
    34021 taatataacc ttatcagcac aaacttatat aaagaacctt tacttatctt gtggttttaa
    34081 agaaatctca gaagtatacg acgaagcagg tattgaacat attaaaatga gattatagtg
    34141 ttgacaagct aatattgtta atatataatt taagtataaa ttaaatattg aattgatatt
    34201 taggtatttg aaaatacctt acatagagtc agaaggcttt tgctttctga cttttttatt
    34261 atcaaaattc aataattata tggattcaaa gtgttaattt ttattctata ttctactttc
    34321 cccaaaagta agaattatac ccaactttgt atgataggca tcttgcctat cttttttttg
    34381 taaaagtaac aaggtaataa tataatgcat agtttaaaat aagaagatta gcccaggcta
    34441 aatttcaagc atggaggtgc tattatgaaa aaccttaacg atattcaagt gaaaaaaact
    34501 gtcaaagttg aagatatatt atctagtggt aatttaagag aaagaatgtt agcgcttggt
    34561 cttactagag gagctgttat agatgtagtt agaaaaggtc caaaaaataa tttaactgtc
    34621 tataaaatca gaggtagcaa gatagctcta cgacaagaag aaagtagctt aatattagtt
    34681 tctgacattt aaaaatttct agcaggagga tattaatatg gggttgacac ataactcaac
    34741 taaaatgagt tctttaaaag acatgtttga tatagacaat aaggaagacc agtttgtaat
    34801 tgcattggct ggcaatccaa atacaggtaa aagtactgta tttaatcatc ttacagggct
    34861 tagacagcat actggaaact ggccaggaaa aactgtagct acagctcgtg gtaattttaa
    34921 atataaaaat accgaatatg cattaataga tttaccagga acatattctt tatttgcctt
    34981 atcacaagaa gaaattgtag ctcgtgattt tatatgtttt ggtaatccag atgcagtaat
    35041 agtagtatgt gatgctacat gtcttgaaag aaatttaaat ttagtatttc aagtgatgga
    35101 acttacagat aaagttattt tgtgtattaa tttaatagat gaagctagaa aaaaaggcat
    35161 tactattgat aaaaaacttt tagaggattc tcttggtatt ccagttattt taactgctgc
    35221 aagaaatggc tctggtatgg atgaactatt ggatacttta aatgatgtat cttttgacaa
    35281 atacaaatta aataataaac ctgttagata caatgaaaat atagagaatg tggtaaaatc
    35341 aattcaacca gaattggata atattatacc aggtataaat tctagatggt tgggacttag
    35401 acttattgat ggcgatgaaa gtatatttga atctatgagt aattatatag acaaagattc
    35461 tatagatgct attaatgaag taaagaaaaa gattccagac aatataaata aacagaaaat
    35521 aagagatgag tttactaaaa tcaactatga ttatgctaaa aaactgagtg atgagtgttg
    35581 ttctaatgtt gctaaaaaat caactgatag agaagaaaaa gtagataaaa tattaacatc
    35641 taaaatattt gggcttccaa taatgctctt attattaggt actatattgt ggattactat
    35701 agaaggagct aactatccat ccactttatt atctaattta ttactcggat ttgagccaag
    35761 tatttcgggt atattaaata gtattaattg tccatcatgg ttaaatgata tgttggtttt
    35821 aggattatac agaacattag catgggtaat ctctgtaatg ctacctccta tggcaatatt
    35881 ttttccatta tttaccttac ttgaggattt tggatatttg ccaagagttg catttaactt
    35941 agaccaccta tttaaaaaag cttgtgcaca tggaaaacag tgtttgacta tgtgtatggg
    36001 atttggatgt aatgcagctg gagttattgg ttgtaggata attgactctc caagggaaag
    36061 acttatagct atacttacaa acaactttgt tccttgtaat ggtcgttttc ctactttgat
    36121 agctatatct acaatatttt ttagctcagt tataaccaac tctttcgtat caagtgtagc
    36181 aactgcactt tgcataactt tactgataat tctaggtgtt ataataacat tgttggtttc
    36241 ttatactctt tctaaaacgc tattaaaagg agttccgtct acatttacat tagaacttcc
    36301 tccttataga gttcctcaaa taggaagaac tttatatacc tctataatag atagaacaat
    36361 atttgtttta ggaagggctg taatggtagc catacctgct ggtgtcataa cttggatatt
    36421 tgcaaatata tatataggag atttaagtat attatcacat gttgcaaact ttttagaccc
    36481 tttagctaaa ttaattggtc ttgatggttt tatattactt gcttttattc ttggattccc
    36541 agcaaatgag atagttgtac ctatactttt aatggcttac ctagcaactg gttctatgat
    36601 agaattagat agctttagtg ctttaggtca agttcttaga gaacatggat ggacttattt
    36661 gacagcttta aatgttatgc tgttcagttt actgcattgg ccttgtgcaa caacactttt
    36721 aacaataaaa aaagaaactg gtagtttaaa atggactgcc ttaggattct taatgcctac
    36781 tatacttgct tttgttgttt gttttttaac aactacagtt tacaatttat ttatataatt
    36841 agtattaact gacattagac atatattaga gaaactattt aaaaatttat atactttatt
    36901 ataaagcata gagatatatt caatgataag taaaattact taacatttga atatatctct
    36961 attttaattc ttatctggat acttggattg aaatttcagt catataatta tcttcattac
    37021 tttcacaaaa aaagtcaagt atactctcct catacgaatt tccaataatt ttatattcat
    37081 tttcatatat atattttttc aatttttcgt aagatttata tgaatcctca tattttccaa
    37141 tatgttttat gcaagcatac attccttctg gctttacata tagcttttta tcctttattt
    37201 ttttatctat cttcaaataa aaacttgata tacttaaata gtccccattt tttatatttt
    37261 cattacttac tattactccc aactcatatc cttgatacaa atttttcgat ttacaataat
    37321 tggtgaaatc tattaattcc atcataaaat cactattact catattactc aaatcgcttg
    37381 atagaactaa atattcttca aactttttgg atatataaat ttcttcacta ttcattttag
    37441 aaattccttc aactgttata tttattctat tttgcatctt agaacttatc tttcttagtt
    37501 tttttatttt ttctcttatc tttttttctt cttctttaag cattttcaca caaagctggg
    37561 gagttctatt ttgtatatac tcttttattt cctctaaact cattcctatt tctctcaatg
    37621 attgtaatat atcaagtgta tcatattgat aaactgagta atatctataa ttatttttat
    37681 ctttatattc aggagaaaaa atacctattt tgtcatagaa aattaatgtc tgcttagata
    37741 taccacacaa tttagcaaat tcacctgttg taaaatactg tttttccaag ggttatacac
    37801 tccttttctt tttgttgtct atatagttac tatattcttt attatttact aaatcaagta
    37861 gttattattt tagaaaatca atatggtttt gattttaaag cttaaatgtc agttagatgt
    37921 cagttataaa tattttatcc attcccatca taaaaaagat atcccctctt aacttttgga
    37981 tggaatatta tatttatact tgttagagtg aaaattgtaa taggtgctac aataagatat
    38041 ttaattaaac ataaagttaa ttattgtaat aaaaaatctt tagataaatt agagttaaag
    38101 tatggaaata tagatagaga aaaagctgtt aaactagaaa tattttatca gtatttaata
    38161 gaacttgaat atatagaaat gagtttatta ataagaagat tagatactgc aataacatca
    38221 ttagcattag tatctattat aacaatagca tcatattatt taatcagaaa aaatgtgtaa
    38281 ttatgtaagc tatttataat aaaacactga taaaattaat aataaaaagg taataggatt
    38341 tctatactac ctttttgttt ttataatata gtgtaatttt attatatttt tgtatgctaa
    38401 tgtaactaga taatcataag ataacacatt aaaagaaaat tatgaaaact tacattctgt
    38461 atagttaata taaaacataa gtaatataaa tttatgtaaa gcaacaaaag atagatttac
    38521 attccatata gttaatataa aacgaagttt acatttttat tttagaatat aagtcgttgt
    38581 aatttacatt ccatatagtt aatataaaac cttagagaaa gcgaaaacgt accattaaaa
    38641 tcaaatattt acattccata tagttaatat aaaacttgta gttaatatta taattccaac
    38701 tcctataagt ataatttaca ttccatatag ttaatataaa actattgctt aaacttttaa
    38761 gacaaggtgg agcttaaaaa tttacattcc atatagttaa tataaaacta tccaaccaat
    38821 tctatattta tcattccaag aacgatttac attccatata gttaatataa aactttcctc
    38881 taaagtccaa acaccctcta gctttcccgt atttacattc catatagtta atataaaaca
    38941 ccaaaataaa cttagtattt tcaacactta cacgtataca actctcctaa atttgcagtg
    39001 aacgagcaat agtgcaattg ataacgctta tcatgcactc tcaacgcctt atatttcaac
    39061 tgttacgcca aattttttca caaatatcgc tcactgcaaa attcctataa ttttattata
    39121 tcataaatat attacttttg aatattgata ccaatttata ccataataaa agcaaaaaaa
    39181 cgtaatctat ctacattaga tttaaattct ataacttaaa gttttttaca taatatttat
    39241 gcttgtttaa tcaatctaat atatcattct tgtatattgc ttttaatagt cttttttctt
    39301 aaataaatat ctatctgaac aagcatagtt taattaaaaa cttttgtatt cccttaaaac
    39361 tgtatctacc tcttattatt ttatttatga tatattattt ttaatctaaa aatagatatc
    39421 tatttttatt atggttatcc ctttttaaaa tactttaatc atatactatt cccaatttaa
    39481 catccattga aatgctattt tcttatattg caatttataa ttgatatatc ttcaatataa
    39541 taatttaatg tatttttgat tttaaagctt ttcagtgata ttattgataa attagaatta
    39601 attatctagc tttaaaaggt caaagatttc tgttgctgtc tgcggttttc caaataaata
    39661 tccttgtatg taatctggct ttatttgttt aactaaatca tactcttctt gtgtttctac
    39721 accttctaaa catactttta ttcctacatc atgacaaatt gcaacaataa aatgtataaa
    39781 tgtagcatca aacttactct ttaatatatc tttaacaaat actctatcaa ttttcactat
    39841 atctattgga gaaaatttta aaacttctag agacgagtat ccagtaccaa aatcatccat
    39901 agcaatataa attcctaaat cttgtaaagc cttaaattta aactgtaaaa tactcatatt
    39961 ttgtactgta tgactttctg tcaattctaa aacaagattt tgataaggaa aattttcatc
    40021 atctataatt tttactatat cttcaataaa tgtgtcttct aatatttgaa cagctgaaac
    40081 gtttacactc actttaaaaa aaggatagta atcaatccat ttcctaaaag tacgtaatgc
    40141 cattcgaagc acccaagccc ctacaatatt tatcatatca ttttcttcta atattggaat
    40201 aaattccaaa ggagaaattg ctttgcattt gtcattagtc caccttaaaa gaacttctac
    40261 acctattatt ttatgacttt ctgtatctac ttgtggctgg aatcgaagac taaaccccct
    40321 aaaatcatca ttaattgatg cctttaaatc ccgcatcatt tctaatgaat acattttatt
    40381 ttttaatatt tcttgggaga aaaaaacaag cctgttttta ccatgctctt tcgcatattg
    40441 taaagagtaa ctagcacact tataaagttc ttttactgta tctccatgtt ttggatatat
    40501 tacacaacca gcagaaattg ttatatttaa tccatatttt ctccatagtt gaaggtgtat
    40561 aatcatattc tgtatttgat tatatagagt tagaatttca ttttcttcaa cattatcaac
    40621 aagaatgccc atttcgtccc catcaagttt ataaagttca gcattatctg gtaaaataga
    40681 ttgtacagac tgtgctagtg tttttattat attatctcca aaatccctat catacatctc
    40741 attaacattt ttaaaatcgt caatatctaa taatactatg cataattttt caatcatagg
    40801 atttgaaatt ttatcttcaa atacactcat aaattcatga taattcagta actgtgtcaa
    40861 tgaatcaatc ttattttgtt tacctaattg cgtcattatt cctgcaaaaa tacttggctc
    40921 tccaaattca tcacgcatta gttgacctct acatcttaac catatatatt ctccactacg
    40981 atttttagcc ctaaattcca ctgtatgata atccatctgg tttttaccta tttcagtgtt
    41041 tgacttataa aaacgattcc agtcttctgg atgtacaatt tttttccagt aaacaagcgg
    41101 atttttaaca atttctcctg gtaagtcaaa taattcaact tgtgatggtg aatatcgaaa
    41161 tacgcctgtt ttcatattgc aaatgtatat atattcatct gtacctctaa tcaaagcatc
    41221 gtaaagcaat gtagaattat aatcaaaatt gtctcttgaa aaattaaaaa ctcctttttc
    41281 ttctttatta tttgatattt catgaaattc attaatctta attggtttat ttaagcttgt
    41341 tgagtttgca atatctattg attgatgcat atgaacaact gtgccatctt gccatgtaat
    41401 taaactatca taattttcaa aaacacgatt taacttatta catttttcat accactttat
    41461 taatactcct tttttatcat tctttaataa ttctaaaact ttacaaaaac tacaagtaga
    41521 atttttttca ggatataata cttgccaaca aacttttcct tctggatcta aaatattata
    41581 ttcttctttc atttttttgt tcataaaaat aatttcatta gtatgaatat ttgtaacata
    41641 tatattaatc tgtagttgat ttaatataac ttcaaaatta tgtttgttca tatacttatc
    41701 tcctccatag ttactgctct ttataacaac attgttaaaa ttattctttt tagaagattt
    41761 acttataact tatacatata cactaaatac cttaatttaa ttagaaagtt tattacttca
    41821 tattttaaat tataattgat aaaaaaaaat acagcaatat agtattacca atttaaaaaa
    41881 aattaatatt acataataca tctctctctt atattaaatt ttaacttggt actaatcttg
    41941 acaaattgtc cacaaaaata aattatatat tttattattg ttttaaattt ttataaaaaa
    42001 tcagtattat tgatactatt gaagttaaaa agcattaatt tctaaaaaca tcataatttt
    42061 tctaatagac ttaatcactt ttaatatata tagtaaaaca aaaaacttat attttataaa
    42121 tatcataatt tttttactga tattttatta tataaatttt atagaattaa ttgtcaattt
    42181 tttatgaaaa tggtaagata tttatggatg gtatcttgtt ataagaacta tactttaaat
    42241 gtttttaatt attttgtctt atgtaactca tatcctcagg aatgagatta gaaattaaga
    42301 tgttgtatca caaagtggag gtgatactat taaaataggc tttattggtt ctggaaaagt
    42361 tggaacatct ttggcaaatt attttttatc aaaaggttat tgtgtttcag gcttttatgg
    42421 aaggaatcaa ttatctttat tagaatcaac aaatttaaca aaaacaaaga tttacagcaa
    42481 tttgaaagat ataatttatg aaaacgatat attatttatt acaacatcag atgattctat
    42541 tgaaattata gacaaaaaac tttccaaatt taatttaaaa cataaataca tttgccacac
    42601 aagtggctct ttaaaatcta gtatattgtt ctgttcaaaa aaagcaggtg cattaattta
    42661 ttctatccat cctatatttg cattttccaa taaaaatacc aacataaaaa aaatgaaaga
    42721 catttgtttt tccatagaaa gtgataatga acaagatgat ttagttattc aaaatttcat
    42781 agatgatttg ggaaaccaat tttttataag agataaggat acttcagcca cttatcattt
    42841 agctaatgtt ttagtttcaa atttagtatt atctttacta gatataggag taagttactt
    42901 tattaaatta ggtttatctg aagaggaatc tttaaaagct atcagtcctt tagtaaaaaa
    42961 aaatatagaa aatatacttg ataatggctt tactaaagct cttactggtc ctgtttctcg
    43021 tggagatata acaccaataa gaaaacatct atctgtattg gataaaaaag atgaggatat
    43081 ttacaaaata ctatccttaa acatactaaa aataattgcc ttaggaaatg acaattcatt
    43141 aaaaggtata aaaaatatta ctatagaaaa tgcaatcgaa aatttaataa gtaaatctga
    43201 aaaatacaaa gaaatttaca aacttttagg aggaaaaaac gatgaaaaat accatacaga
    43261 cttttaagaa tgctaaatat gaaggaaaaa aactatctat gcttactgct tatgactact
    43321 caattgcaaa aataatggat gagtgtgata taaatggtat tttaatagga gattcattag
    43381 gaatggttat aaaaggtgaa gaaaacactc tatctgttac catagacgaa attatatatc
    43441 atacaaaagc tgtaaaaaat ggtgttaaaa atgccttaat cgtaagtgat atgccttttc
    43501 tatcttacca tgtttctata gaagatgcag ttaaaaacgc cggtagactt ataaaagaag
    43561 gaggagctca tgctgtaaag ttagaaggtg gctcaaacgt tataaagcaa atagaaagca
    43621 ttgtaaatgc tcaaatacct gtaatggggc atttaggatt aactcctcaa tcagtaaatt
    43681 catttggtgg gtttaaggtt caaggaaata ccagtgaaac agcaagacaa cttattgaag
    43741 atgctaaatt aatagaaaaa gcaggtgcat tctctattgt ccttgaagga gtgcctacga
    43801 aaatagctga gatggtaact aattctattt caattcctac aataggtata ggggcaggaa
    43861 ttaactgtga tggacaaatt ttagtttatc aagatatgtt gggaatgttt ggagattttg
    43921 ttcctaagtt tgtaaagcag tatgcaaata taggagatat aatgaaagat tcaattaaaa
    43981 attacatcct agaagttaat acaggtgcat ttccacaaga aaaacacagc ttttcaataa
    44041 atgaatctga gttagaaaaa ttatactaat attaaggatg gtacaaaatg cttgtaaaag
    44101 aaattaaatt actaagaaat ataatcaaag attggagaaa acatggctat tctatagggc
    44161 ttgttacaac aatgggattt ttacatgaag gacaccaaag tcttataaaa aaagctataa
    44221 aagaaaatga taaagtagta gtgagtgtat ttgtaaatcc aactcaattt ggaccaaatg
    44281 aagattttaa tagctatcca agagatatag ataaagattt taaatattgt atggatagtg
    44341 gagcaacagt agtctttaac ccatcaccag aagaaatgta tttaaaaggt aattgtacta
    44401 ccattaatgt ttctggactt acagattttc tttgtggagc taaaagacct gttcattttg
    44461 gaggtgtctg cctagttgtt tcaaagtttc taaatatagt aacacctgat aaagcttatt
    44521 ttggagagaa ggatgcccaa caattagctg taattaaaag aatggtcaag gatttaaaca
    44581 tagatacaga aataataggc tgtcctataa ttcgtgaaaa tgatggatta gcaaaaagtt
    44641 cgagaaatac atatctctct gaggaagaac gaaaatctgc tctaatatta aataagagct
    44701 taagtttagc aaaagaagaa ttagtaaaag gcaatctaaa tccagagaat ataaaagaat
    44761 taataacagc taaaataaat tctgaacact tagcaaaaat agactatgtt gaaattgtag
    44821 atagtgagac attacaacct gttaagcaaa tagaacattc tatacttgtg gcaattgctg
    44881 tgtttatagg aaaaaccaga ctaattgata attttacatt tgagttaaat atataatcta
    44941 taattttata taatatatct aaaaaataat agaataccta aaaagtaata aattac
//
LOCUS       DAEOTL010000028        42600 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEOTL010000028 DAEOTL010000000
VERSION     DAEOTL010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.028"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(89..745)
                     /locus_tag="KRH82_001804"
     CDS             complement(89..745)
                     /locus_tag="KRH82_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8655085.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILAEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(800..1429)
                     /locus_tag="KRH82_001805"
     CDS             complement(800..1429)
                     /locus_tag="KRH82_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBG8655086.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(1560..2201)
                     /locus_tag="KRH82_001806"
     CDS             complement(1560..2201)
                     /locus_tag="KRH82_001806"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBG8655087.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(2210..2881)
                     /locus_tag="KRH82_001807"
     CDS             complement(2210..2881)
                     /locus_tag="KRH82_001807"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBG8655088.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANIIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(2886..3770)
                     /gene="rsgA"
                     /locus_tag="KRH82_001808"
     CDS             complement(2886..3770)
                     /gene="rsgA"
                     /locus_tag="KRH82_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBG8655089.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLVLEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(3868..4605)
                     /locus_tag="KRH82_001809"
     CDS             complement(3868..4605)
                     /locus_tag="KRH82_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBG8655090.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(4713..6728)
                     /gene="pknB"
                     /locus_tag="KRH82_001810"
     CDS             complement(4713..6728)
                     /gene="pknB"
                     /locus_tag="KRH82_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBG8655091.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(6745..7497)
                     /locus_tag="KRH82_001811"
     CDS             complement(6745..7497)
                     /locus_tag="KRH82_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBG8655092.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(7517..8548)
                     /gene="rlmN"
                     /locus_tag="KRH82_001812"
     CDS             complement(7517..8548)
                     /gene="rlmN"
                     /locus_tag="KRH82_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBG8655093.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(8556..9881)
                     /gene="rsmB"
                     /locus_tag="KRH82_001813"
     CDS             complement(8556..9881)
                     /gene="rsmB"
                     /locus_tag="KRH82_001813"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBG8655094.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFILDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQGVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(9943..10644)
                     /locus_tag="KRH82_001814"
     CDS             complement(9943..10644)
                     /locus_tag="KRH82_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBG8655095.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(10713..11465)
                     /locus_tag="KRH82_001815"
     CDS             complement(10713..11465)
                     /locus_tag="KRH82_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBG8655096.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(11475..12404)
                     /locus_tag="KRH82_001816"
     CDS             complement(11475..12404)
                     /locus_tag="KRH82_001816"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBG8655097.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(12419..12859)
                     /gene="def"
                     /locus_tag="KRH82_001817"
     CDS             complement(12419..12859)
                     /gene="def"
                     /locus_tag="KRH82_001817"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBG8655098.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEDLIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(12877..15402)
                     /gene="priA"
                     /locus_tag="KRH82_001818"
     CDS             complement(12877..15402)
                     /gene="priA"
                     /locus_tag="KRH82_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBG8655099.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(15641..16840)
                     /gene="coaBC"
                     /locus_tag="KRH82_001819"
     CDS             complement(15641..16840)
                     /gene="coaBC"
                     /locus_tag="KRH82_001819"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBG8655100.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(16845..17111)
                     /locus_tag="KRH82_001820"
     CDS             complement(16845..17111)
                     /locus_tag="KRH82_001820"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBG8655101.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(17114..17731)
                     /gene="gmk"
                     /locus_tag="KRH82_001821"
     CDS             complement(17114..17731)
                     /gene="gmk"
                     /locus_tag="KRH82_001821"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBG8655102.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(17761..18642)
                     /locus_tag="KRH82_001822"
     CDS             complement(17761..18642)
                     /locus_tag="KRH82_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBG8655103.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(18646..19476)
                     /locus_tag="KRH82_001823"
     CDS             complement(18646..19476)
                     /locus_tag="KRH82_001823"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBG8655104.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(19763..20797)
                     /gene="ltaE"
                     /locus_tag="KRH82_001824"
     CDS             complement(19763..20797)
                     /gene="ltaE"
                     /locus_tag="KRH82_001824"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBG8655105.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            21093..22868
                     /locus_tag="KRH82_001825"
     CDS             21093..22868
                     /locus_tag="KRH82_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBG8655106.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSRFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(23083..24735)
                     /locus_tag="KRH82_001826"
     CDS             complement(23083..24735)
                     /locus_tag="KRH82_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBG8655107.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCGHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     EGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEIKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEKKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYIISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQITKLKNSF"
     gene            complement(25034..26245)
                     /locus_tag="KRH82_001827"
     CDS             complement(25034..26245)
                     /locus_tag="KRH82_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBG8655108.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(26530..27063)
                     /gene="pyrR"
                     /locus_tag="KRH82_001828"
     CDS             complement(26530..27063)
                     /gene="pyrR"
                     /locus_tag="KRH82_001828"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBG8655109.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(27423..28370)
                     /locus_tag="KRH82_001829"
     CDS             complement(27423..28370)
                     /locus_tag="KRH82_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBG8655110.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(28339..28785)
                     /gene="lspA"
                     /locus_tag="KRH82_001830"
     CDS             complement(28339..28785)
                     /gene="lspA"
                     /locus_tag="KRH82_001830"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBG8655111.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(29092..29871)
                     /locus_tag="KRH82_001831"
     CDS             complement(29092..29871)
                     /locus_tag="KRH82_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8655112.1"
                     /translation="MKKIIWGICICLLSIVGVYTYSHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDGGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(29926..30408)
                     /locus_tag="KRH82_001832"
     CDS             complement(29926..30408)
                     /locus_tag="KRH82_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBG8655113.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDISLCNDCANKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(30674..32095)
                     /locus_tag="KRH82_001833"
     CDS             complement(30674..32095)
                     /locus_tag="KRH82_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBG8655114.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(32241..33011)
                     /locus_tag="KRH82_001834"
     CDS             complement(32241..33011)
                     /locus_tag="KRH82_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655115.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(33016..34218)
                     /locus_tag="KRH82_001835"
     CDS             complement(33016..34218)
                     /locus_tag="KRH82_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBG8655116.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            35084..35830
                     /gene="cdtR"
                     /locus_tag="KRH82_001836"
     CDS             35084..35830
                     /gene="cdtR"
                     /locus_tag="KRH82_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBG8655117.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
     gene            36219..36401
                     /locus_tag="KRH82_001837"
     CDS             36219..36401
                     /locus_tag="KRH82_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655118.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            36619..36762
                     /locus_tag="KRH82_001838"
     CDS             36619..36762
                     /locus_tag="KRH82_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655119.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            36737..38304
                     /locus_tag="KRH82_001839"
                     /pseudo
     CDS             36737..38304
                     /locus_tag="KRH82_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(38956..39957)
                     /gene="trpS"
                     /locus_tag="KRH82_001840"
     CDS             complement(38956..39957)
                     /gene="trpS"
                     /locus_tag="KRH82_001840"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBG8655120.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(39980..40678)
                     /locus_tag="KRH82_001841"
     CDS             complement(39980..40678)
                     /locus_tag="KRH82_001841"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBG8655121.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(40721..40961)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41052..42455)
                     /locus_tag="KRH82_001842"
     CDS             complement(41052..42455)
                     /locus_tag="KRH82_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8655122.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
BASE COUNT        14035 a         7505 c         4414 g        16646 t
ORIGIN      
        1 caataaaacc tactttttaa ttttttaaat atttattttt aatttatttt gtttttaatt
       61 tacttcgatt ttaaaatgtc cttgactttt attttataaa tgtacatatt tcttctactg
      121 gttttttaga tggactcttc aaattgtcct ctggcactcc aagagctaac attgcaccta
      181 aaaaatactc tcccttttca aaaccagttt ctgcttctaa aacagcttct atctcatctg
      241 ctgcatagtt ttgacttgtc aaccaacaag aaccatatcc aagttcaatt gctgatagtg
      301 taaagttttc aattgcagca cctagactct gcatacctgg atttcttata aataatttat
      361 ctatagtctc cttaggtgca tctataagct ctaattcata atatcctgat gggttatata
      421 cctttgtaaa aactaatact aaaactggag cttttaaata aaatagtgta aagtttttaa
      481 caaattttct aaatctatta gccttatcca ctgatacttt atccatttct gcaagtattt
      541 cttgttgctt tttagttatc acatctgcta tcttttccat taaatcacgg cgttttataa
      601 caacaaaatg ccagttttga atattcttgc ctgatggtgc tgcacctgct gcttttatca
      661 tttttaaaat atcttcatct gatacatctt gatttttaaa ctttcttaca ctttgtcttt
      721 taaaaatagt atcttgtaat tccattttta aatcccccca taactttttt attattttaa
      781 tataattttt aaactcatct tattttaata tatcatgttc taacaaatct ttaaatgagt
      841 ctataaaata atcatataca tctacattcc caaacccata tttggcatat ataaaaggta
      901 tacctacaaa cttagcacta tttgcatcac cttgcgtatc accaacatag attggattta
      961 ttaatttatt tctttcaatt ataagtttat tattttctcc tttatgcaaa ccagtattac
     1021 caggacattc aaaatctata aaatactgtt ctagtttatg tgcttttaaa aaagattcta
     1081 tatatccagc ttgacaatta cttactataa ataatttata ttttttagat agtaatttaa
     1141 gagtatcttc tatatcatca aataatttag ctccattttc agataaatag tcacattctt
     1201 tcaaagaaca ttcattcaat aaattcattc tttcttcttc acttaaattt ggaaataaac
     1261 gatttgctat ttcctcaaaa gaaagcccca taagacttct aaataaatct tttgtgacac
     1321 ttaattctat ttccttatgt ttacttaaaa catcctgcca gactttgcat acttcttcag
     1381 ttgaatccca caatgttcca tctaaatcaa aaataatact atctaccaca aaaaatcccc
     1441 cttatgtcaa agtttattat atatttataa ttatatacta aaaagcagat acaatcataa
     1501 atatatttta cttgattgta tctgctctac aatataaaac caattgtcaa aatcaaattt
     1561 tataaatttc taactacaag tacacagcct tgctctactt taatcttaca agaattactc
     1621 aacataacat ttgatattcc aataggtaca gagtatttca tataataatt atcgagaggg
     1681 tattctaagc cagtaagtgt tacaccctta gcatcaccat ttatagctat tacagaaata
     1741 gtgtcccctg ggtttccata caatgaaatt tcctcatttt caactatata catctcttct
     1801 ttatcagaaa gtatcctaga atatatacca tcttctttta aataatataa tagctttata
     1861 tttgcaagag tgtggtcaat ccttccccct aaagcaccaa aaaaatcaat atgatttgct
     1921 ttaagtgtct tagctaaaaa aagacaaagc tctgtatcag tctcatcttt tttagatgga
     1981 aatttttcaa atttaacacc tttattttta tagaaattta tcttttcttc ttctactgaa
     2041 tctaaatctc ctaatatata atctggcatt atttccattt tataagtgtg atttgcccct
     2101 ccatctgcac atattatgca gtcataacat tccttaatta taatatctct tgtaacttcg
     2161 taatcttcaa tttcgccatt taaaacaata cagattttca ttattaaatt taaactaatt
     2221 cttcaagaga agcattcttt ctaaataaat taactgtttc ttgaatgtca tcacttccaa
     2281 atattgcaga acctgctact attatattag ctcctgcttg tacaacttcg gctacgtttt
     2341 tagggcttat accaccatca acttctatat caatgtttaa tccttgacta tctataatag
     2401 cttttaactc tttaatctta tctaaaacac aaggaataaa tgattgtcct ccaaatccag
     2461 ggttaacaga cattaataat accatatcta aatcaggtag tacatgttta atcgtatcta
     2521 ctggtgtagc tggattaagt actacaccag cttttattcc atgtgatttt atattttgta
     2581 tagttctatg tagatgaaca caagcctcct ggtgaacagt tattatatca catcctgctt
     2641 ttacaaattc ttcaatatac tggtctggat tttctatcat aagatgagca tcaaatacca
     2701 tatttatatt ttctttcttt aaacttttga ctacaagtgg tcctaatgta atgtttggta
     2761 caaagtgtcc atccattaca tcgatatgaa gatattcaca tcctgcactt tctacttttc
     2821 ttacatcttc taataatttt gcaaaatctg ctgataatat tgatggtgct aatttaatca
     2881 tgtttctaat acctcctact attattttgt cttatttcat gtagcagctg tatataacta
     2941 tcatatcttt ctttagatat ttctccattt gtaacagctt cttttatagc acaattaggt
     3001 tcattttcat gaatacactt tgaaccaaac ttacaatcat taaatttatc aaattctata
     3061 aaataatctt taagttcaac ttcctctata tcttcaagga caagggaact aaaacctggt
     3121 gtatctgcaa ccattccacc aaattctaat tttaaaagtt cagcgtgacg agtagtatgt
     3181 tttccccttt ttattttatc acttacaact cctgtttgaa gtttaaaatt ttcatctatt
     3241 tcatttaata agcttgattt tccaactcca gatggtcctg caaacactac tacattttct
     3301 tttaattctt cttttacttt atctatattt aacttagtaa tattacttac aggaatgact
     3361 ttatagccac taagttcata tatattttta acagtttcta atgtatcatt atcatctaaa
     3421 tctgcttttg taaggattat tacagtttct aaattttctt tttctgccaa aactataaat
     3481 ctatctaaaa gagataagtt tggtttagga ttttttattg cgaatactat taatgcttta
     3541 tctacatttg caataggagg tcttataagt tctgtatctc tactgtcgat ttcttctaag
     3601 ataccctttt tttcatcttc atcaacaatg cttattttga ctctatcacc aaccaaaggt
     3661 gttattttct gctttctaaa tatccctcta gccttacatt cataaatacc attataagta
     3721 tctacataat aaaatccact aatccccttt ataatttttc cttctagcat caaatgcctc
     3781 cctttataaa atttatataa acacatactg tttatgagta gtatatcgtg ttattctttc
     3841 ctatttttat ataataccac atttttttta aataacaaat cctccgtttg gactaattac
     3901 ctgaccagtg ataaaatttg atttgtctga tgccaagaaa atagcacaat ttgctatatc
     3961 ttctggagtt cctagcctca ttagaggggt ttcttccaca agagcgtcta tatcttcctc
     4021 attatatcca gataacatgt cagtattaat gacacctgga gctatgctat ttactctaat
     4081 atttgatggt cctacttctt tagctaatgc ctttgtcata cctattatgc ctgcttttgt
     4141 tatagaataa tgcacttcac aagaggcacc tgatataccc cagattgaag atatattaat
     4201 tatatttcct tttttttctg atatcatgta ttttaaagca acttgtgaac aataaaagct
     4261 tccttttaaa ttaatattca tcatattatc ccaatcttca tcagttatat ctgtaaacaa
     4321 cttatcttga cttacaccag cattgtttac aagtacatcc aatcctccaa attcttttat
     4381 acaataatct accatatcct ctacatcttc tctatttgaa atattagcct taaaaagttt
     4441 tacagaaaaa tttttttcat ttaatatagt gtacaactct ttagcttcat tttctgactt
     4501 attaaaattt actaatacat tgtaaccttc ttttgcaaaa gctttagaca tagctttacc
     4561 aatccctcta gctcctcctg taattaaaac tgttttcttc ttcataaata cttttctcct
     4621 tatattataa ccaattcagt attttataca aaacaaactg ccctttaaag aaaatatttt
     4681 ctataaaagg acagctctta ttttattaat atttattctg ttttaccaat gtttgcgcca
     4741 gttcctgatg aagttcctcc attatctcct gagtttgagc ctcctgaact atctccattg
     4801 tctcctgagt ttgaacctcc tgaacttcct ccattgtctc ctgagtttga gcctcctgaa
     4861 cttcctccat tatctcctga gtttgaacct cctgagtttc caccactatt tcctgagttt
     4921 gaacctcctg agttacttcc attattgcct gagtttccac cactatttcc tgaatttgag
     4981 cctcctgaat ttccaccact gtttcctgag tttgaaccag gttctgttgg tgtattattc
     5041 tctggtgttg ttggtttttt atctggtact gttggagtct gtgtatttga tttttctgaa
     5101 cctttgctta catataggtt tacctcatca ccttcctgag ctcttgatga gccagcacct
     5161 ggactctgac ttaaaactgt accttcttta tatattgagc tgtattcata cttaacagtt
     5221 cccactttta agttattttc ttcaataagt tgttttgcat tactcaaagt aagtcccact
     5281 acattaggaa cagatgcctg acttgaacct ttacttacga caacatttat agtatcaccc
     5341 tttttgacat ttgtacttcc accttcaggt gtctgtgata ttatacaatt ttcatcaact
     5401 tcactattat actcttcact ttttacactc aggtataatc cttctttttc aacagcactt
     5461 tgagcttctt ctaatgtcat atttacaaga ttaggaacag tcaaagattt attgccaaac
     5521 cctccagcaa ataaaaactt atatgctaag aatacttgag cacacaatat cagtatcaaa
     5581 acagccgcaa ttacttttaa tcttcttcta gattttgggc tttcctgttt tttcttcttt
     5641 ttcttagttc tcttacttgg agtactctta ggtctctgat tctttttagc tctcattatc
     5701 tcttcctctt cttcatcttc atcatcatct tcttcataaa aatcatcata gtaatcttca
     5761 tcatcatcca aatcagctac ttcaacaggc ttaaccactt tttcaggagc tggttttgca
     5821 agtgttggat ttacaacttt attaatttcc ttttcatcaa ttttcttagt tgcaaaatca
     5881 tcatattctt ttataaaatc taaatcaata tttttttcta tatactctat atcttctatc
     5941 aattcttcag cagtttgata tctatctgca ctagattttt ctgtaagctt ttttattgta
     6001 gttcttacac tttgaggaat cctaactttt tcttctgatg taaagtctat atcatcatta
     6061 atgtgttgaa gtgctataga aattggacta tctcccctaa atggaacttt tcctatcaac
     6121 atttcatata aaactatacc tagagaatac aggtcagcat tattagttac aaatttacct
     6181 ttagcttgct ctggtgaaaa ataatgcact gaacctatta tactaccaat attagtcatt
     6241 gttgaatttg aaacagcttt ggctatacca aaatcagcca cttttactac tcttccttca
     6301 tttgatatga gaatattatg aggttttata tctctatgta taatcccctt tttgtgcgct
     6361 gcactaagtg ccatagctat ttgttttgtt atatctaatg cagtatattc atctaatata
     6421 ccttcatctt gtataatctc ttttagattc ttcccatcta caaactccat tacaatgtag
     6481 tgaacttttc catcttcacc aacatcataa acatttacta tatttggatg tgaaagactt
     6541 gctactgctt ctgcctctct tttaaacttt gttagaaatt catcatcatc tacaaattca
     6601 ggtctaagta ctttaagtgc aacagtcctg tttaataatc tgtctttagc ctcatataca
     6661 aaggccattc ctccatcacc aatcttcctg atgatttcat atcgatttcc taaaattgta
     6721 tctcccacaa tatcaccgtc ctaattatac ttttatcact ataaccgaaa cattatcttt
     6781 accagaaaca tcattggcca tacttatcaa ttcttcactt atattactag ttctctcata
     6841 ttcataatct aatattaaat ctcttatatc ttcatcatca ataaacccag ttaatccatc
     6901 tgtcgcaaga agtattatat cacttttttt gatttctttc ttaaaaatat ctacaacaac
     6961 catatcatct gttccaattg ctctagttat tctattcctc tgtggatgtc ttcttgcctc
     7021 ttcttctgta atgacatggg ccatcataag ttcttcaacc acggaatggt ctatagttat
     7081 tttatcaaat ttttcatctg ttaacaaata acatctgcta tctccaacat ttgccacata
     7141 taagacatta ttatacacta tagccgtaac taatgtagtt cccattcctt caaattctat
     7201 atcttccata gattttttgt gcacaattga gtttacatta ttataagcct gttttaatat
     7261 atcatctata tagtctattt ttacattatc atgttgtaat aagttttcct ttagaaaatc
     7321 aattatattt tctactgcta atttactggc gacttcacct tttttatgtc cacccattcc
     7381 atcagctatg gcaaatattc ctattggacc atgttctgta tctataactt ctccctcaca
     7441 atagtcttca ttgttttttc ttatttttcc tatatgggag gcacaactat aaaccatacg
     7501 acttcctcct tacaaattac ttgtattttc ttctcaattg cccacaagct ccactaatat
     7561 cagaacccat agacatccta actgtggcag gtatattgtt cttctccaaa ctatccctaa
     7621 atttataaat aaatgcttta tctggctttt catattctct ttcttcaact ttatttattg
     7681 gaattaaatt tacatgacat agcatacctt ttaggagctt agctaatgcc tttgcttctt
     7741 tttctgagtc atttacccct tttataagag aatattcaaa tgtaaccctt ctatttgtct
     7801 tttttatata atatctacat gcattcaata tttcttcaat agaataagca tttgctacag
     7861 gcataatttt tcttcgttct tcatcatatg gtgaatgaag tgataaagct aaatttatag
     7921 ctatttctaa gtctgccaac tcatacattt taggtactat tccacaagtt gaaagagtta
     7981 tatgtctata ccctatatta agaccatttt tttcgttaat tatttttaaa aattgttttg
     8041 tattttcaaa gttatcaagt ggctcaccac tccccatcaa tacaagattt gataccctct
     8101 taccagtatc ttcttgaatt ttaataactt ggtctaaaat ttcccatggc tctaagtttc
     8161 taattaatcc atccattgta gatgcacaaa aattacatcc catcctacaa cctacttggt
     8221 tagaaacaca gacagtaact ctactatcat aatccatcat cacagtttct attatatttc
     8281 catcatctaa taaaaacaaa tatttttttg tattatctac cttagattct aactttaatt
     8341 ctatatctat atgccctata catgaaacct cttctaattt atttctcaaa ctttttggta
     8401 tattgttcat atcatcaaaa gtttttgcac ccttatatat ccaagagaat atttgacttc
     8461 ctctaaaggg cttttcatct atagttttca taaattcttt aagttcatct tcagtaaaat
     8521 tttttaatac tatctttttc ttttccattc tctcactacc ttattctctt taattttgct
     8581 atgaaaaaac catctatacc atgaatatta ggatatatct ttaaatatcc tttatcttga
     8641 ttgtctaagt ctacatttac tgtatcaatt ggaacaaatt caaagttgtg attttcttca
     8701 acaaaagaag taactatatt tatattctcc acaccttgaa ttgtacatgt actatatact
     8761 aaagttccac caactttgac atatttagat gcattttcta aaattttctt ttgtatagaa
     8821 gtgatgtcct ttaactcttc ttctttctta tacttaattt ctggtttacg tcttattata
     8881 ccaaaaccag agcaaggaac atctgctaaa acataatcaa atttacttat actattttca
     8941 tcaatctcag aagcatcaaa tctttctaca aacacatttt taagccccaa tctatttaca
     9001 gtagagttta taagctttag tttatgctca aaaatatctc tagctactac ttgaccagta
     9061 ttgttcatta aagtagctaa gtgagtagat ttccctccag gagcactaca tacatccaaa
     9121 ataaatgaac cttcttttgg attaattact ttccctacta tcatagaact tatatcttga
     9181 attgtaaata aaccagcctt aaataattca tttttttcta tatttttcat tttttcgact
     9241 ttaatagctt cttctaccat aggaactttt aaacatacaa tacccatttc acttaatttt
     9301 tcaataagct cttctctact tattttaagt gtattcgttc ttatatagat actaggcttt
     9361 tcattatttg cttccaacaa atcttcagca aattcttgtc caaatttatc tatccagttt
     9421 tttataatcc aagagttata ggaatacttt atagataagt attttacact atcttcctca
     9481 gttatgtcca ttatagtctc tttagctctt atttcatttc taagaatagc atttatgaaa
     9541 ccagaagatt ttttatcata tttcttagat aattttacag tttcattaac tgctgcataa
     9601 tctgatatac tatctaaaaa taaaatctga tatgttccca ttcttaaaaa gattttaaca
     9661 taagttgaca ttttttttac ctttattttt gaaagtttat tgattatata atctaaataa
     9721 tatttatttt ctattactcc ataaattaac tctgttgcaa gtcctctatc catatcactt
     9781 atttctaaat ttttaaaatg cttatttatt gcaatatttg aataattgtc atttttttct
     9841 atatcacata atactttaaa tccaacttct cttgcatcca tataaatttc tcccttttat
     9901 taaacataaa aaagggttgt ttctaaacaa cccactttac ttttagtcat ttcttctttg
     9961 agctattagt aacaatctaa gtaattgaag tattgaaacc aatgctgctg caacatatgt
    10021 taaagctgct gctgaaagta ctcttctact ttgtcttgac tcactttcat ctataatacc
    10081 taaattccca agttgaacga ttgctctact tgaagcatta aattctacag gcaatgttat
    10141 tatttggaat aacactgaag ccgaaaacaa tagtatacca atttttaaaa atggaccagc
    10201 cataataaat cctaaaaata ttaaaaacca agatatactt gaagcaaaat tcactactgg
    10261 tactaaacta cttcttattt gaagaggtgc ataaccttta gcatgttgta tggcatgacc
    10321 acactcatgt gcagctactg caacagaagt tatagatgtt ccataatata catcttctga
    10381 caaccttaca gcctttcttc ttgggtcata atggtcactt agatgccctc taaccatttc
    10441 tatctttaca tcatacaaac catttgaatc aagtactctt cttgctgttt gctctccagt
    10501 atatcctcga cgtgtattta ctcttaaata cttatttgtt gttgaactca ctttaaattg
    10561 tgcatatata gtaagtaata tagctggaat taatacaacc attgttgggt caaatcccca
    10621 aaaaccgcca tatacagggt acataaataa cactctccta aaatatattt ttattataca
    10681 tcctcttaat attcacttaa cttaaaaaca gtttaattac aaactaatat attttttcct
    10741 gttaaaaagc ctatagcttt ttcaatatcc atcatgtcta cattagtatt tacacaaggt
    10801 ccattaggtc ttttgttaaa tacacctaaa acaggaattt ttttaatatc ttgtattcca
    10861 gatgtcaaat ctctttcaca tgcaacagct acaacagctt taggtttagt gtccattata
    10921 atttttctag ctagggttcc tcctgtagct acaaatattt ttacattagt tttttccttt
    10981 agcttaatta attctcctat gttgcatctt ccacattctt tacaattatc tatatcatta
    11041 gtaactttta atttacaact attctcttga atacaatgag gtattaaaat tattatatcc
    11101 tctggattaa aattatattt attactgtat atatattcat tatttaactt tatatatatt
    11161 cttctaatat cactttttga cataccaaat gatgatgcaa tgaaagatat aataggaaat
    11221 aatccactga caatattaaa atttattttc attatatttg agttaacata ctttccttta
    11281 attactctat aagtaactgc tgttgaacat agtattataa gtattagtga tattattata
    11341 atatttatca tcaaggagaa tatttgagtt aaacttatta taaaaaaatt aacaactcct
    11401 atcaaaattc ctaatattaa aatcaaaatc ccaacacttg ttaaatactt ctttatatct
    11461 gtcatacttt tcacctaacc caatactaaa ccagtttcta tagtattccc ttttatatat
    11521 tcaccaacca acattctctt tttattcggc atctgaattt cttcaattaa aagtacatta
    11581 tctatagtac ttacttttat cccatctttg cttacatcaa ttattgtacc tacatctttt
    11641 gtgctttttt catctaacac tttagttttc caaactttca ttatgacatc attataggta
    11701 gtataagcac ttggccatgg atttactcct ctaactaaat tgtgtatttc tctggcactt
    11761 tttgaaaaat ctatgttacc taatgattta ttcattattg gcgcatagga aaattcttca
    11821 tgattttgta cttctcttgg agcatttcct tcttcaatta atcttaatgt ttcttttaaa
    11881 gtttctgctc ctatattcat cattttatca tgaagttctc ctgctgttat attttcatca
    11941 agatttactt ctgtctttag tatcatatct ccagtatcta atccttcatc catatacata
    12001 gttgtaacac cagtcttttc ttcaccattt attattaccc aatttatagg tgccgcacct
    12061 ctatattttg gaagtaaaga aacatgaaca tttatacatc caagtttagg aatctctaat
    12121 atttcttttg gaagtatctg tccaaaagct acaactacta ttacatctgg atttaaagat
    12181 ttaattttat ctataaattc tttatctcta gcctttactg gttgatatac aggtatatta
    12241 ttttcaattg ccagttcttt tactgggctc atacctagtt ttttacctct tccttttggt
    12301 ttatctggtt gagttacaac acccaatatt tcatacttct catctattat tttttgtaaa
    12361 catggaactg ctatatcagg agttcccata aatactattt tcatcaaatc aactcctact
    12421 acttttctat tttgtcaaca aataaaattc catctaagtg gtctatctca tgacaaaatg
    12481 ctctagctaa aagctcttct ccctctaact ctattgtttc accatttcta tttaaagctc
    12541 tgacctttac ataatttggt cttctaacat ttcccgcttc tccaacaaca cttaaacatc
    12601 cttcctcatc tatttgctcc ccagatgttt ctattatttc aggatttata agttctataa
    12661 gatcttctcc aatatctatt actactactc tttttaatat tccaacttga ggtgcagcca
    12721 gtccaacacc atctgcatca tacatagttt ctgccatatc atctaataat tgtattatct
    12781 tttcatcaat tttttcaacc ttttttgatt tttttcttaa tactggttct cctatttgaa
    12841 ctatttgtct taaagccatt ataattcctc ctaaatttat aatacactgt ttggattaat
    12901 atctatagat acattgatat tcttatcaaa tatcaaatct cgttttgtta tacatatata
    12961 ttttattata ccctttaaga gattaatttc aatattttca tctttaaaga gtatttgcca
    13021 tctataattt tgatttattt ttgatattga acatggattt ggacctaata taaatcctaa
    13081 atcatttata cccctttttt ctaataaata aatcaatgat gcatgcatat tttttatatt
    13141 ttttatcact aatctttcat cttcaccact aacaactaca cttaacatat tattaaaagg
    13201 agaatatcca aatgcttttc ttatttttat ctcatcttca taaaaaccct cataatcata
    13261 ttcaatagca tgcttaatag catagtgttc agtgtcataa gtctgaagta ctacttttcc
    13321 ctctttatca gctctccctg ctcttccaga gacttgagtt atcaattgaa atgtagtttc
    13381 aaaactttta aagtctggaa aatttaatat catgtctgca gacaaaatac ctactaaagt
    13441 tacattctca aaatccagcc ctttacttaa catctgtgtt ccaataagta catctgcttc
    13501 tttatcttta aatttattta atatctcatc taaagcacct ttttttgaag ttgtatcttt
    13561 atccattctc aaagttttta tatctggaaa aatatatttt aattcctctt caattttttg
    13621 agttccaact ccaaatggct taacataagt acttttacat tcaggacact cttttggaat
    13681 ttctttctca tatccacaat agtggcatct tccagtatta cttttcttat gataagttaa
    13741 agatatatca caattttcac attgaaacac atatccacac tttctacaag atacaaaatt
    13801 tgcataacct cttctgttta aaaatagtat tacttgatta ttttcttcaa tcgcataacg
    13861 tatttctttt tgtaatttca aactaaatat acttctattt cctttatcta actcatcttt
    13921 catgtctacc acttcaatgt ttggaagagg cttatcattt gctctacttt ttatatttat
    13981 aagtttgtat tctccagatt ttgccctata atactcttca attgagggcg ttgctgaacc
    14041 taaaataaga gttatattat tttttaatgc cataaatcta gcaacttcta tagcattaaa
    14101 ttttggattc ttctcagact tatatgatga ctcatgacat tcatcaatta ttattaagcc
    14161 taaggaatta aaaggtgcaa ataaagctga cctagctcca attaacactc ttactttacc
    14221 tgctttgaca gctttgtaaa catcatgttt ttctccttca gatagtttac tgtggaacac
    14281 tccaactaaa tctccaaacc tactctttag cctatctatt gtttgaggag ttaatgctat
    14341 ctcaggtact aagaatatac tgtctaagcc ttgatttaga gcaaattcta ttatttccat
    14401 gtaaacttca gtttttccac ttccagttac tccatgaatt aagtatggtt ttttatcatc
    14461 tacaaacata ttcgacttta tctcatcaac tgcttcttgt tgctcattgt ttaattttat
    14521 actttttagt acggatttgt aaatactttt tggctctcta taataatcct taaattctag
    14581 ggttattagc tttttcttac ttagagaatt tatactttgt tttgaagcat ttaataaatc
    14641 caataaatca tttatctcta cattttcatt atttttaaga aaacttaata tctctttttg
    14701 tttacttccc acatttattt tattttgctc tatataatcg tcaatcttat cactttctaa
    14761 actcaaagat atataacata ctttcttttc atttttgtga tttttatatt cccaacataa
    14821 ttttataatt ccatttttat tcattgtgta caaagaacta tttaagtttg gtatatattt
    14881 taacttatca accttaattt tacctttact atcaatcact ttctctacta tttctctatt
    14941 tttatcactt aaagttgata ttttttcctt caattcaata tcatttaatc cacttaaact
    15001 ttcacctaat aggactactt tataattatt taatttgtat ccctttggat atatcaaatt
    15061 tatacattct atataagtac acaaatatct atttttcatc caataaacca actctaaatc
    15121 ttcttttcta aatattggat tttcatctaa tatatcaata atttctttta tttttatttt
    15181 ttcatctaag ctatctgtaa attgaaatac aaaggcttct gttggtttat taccttttcc
    15241 aaatggtact aatattctgt gcccgatttt tattacatca gataaaaata caggaatttg
    15301 atatgtaaat aaattatctg tatatatagt attacttcta actattacct ttgcatattt
    15361 tttcattata aaacctctac ttaaatttaa tatattgttc atattttaat atactttaca
    15421 agatattaaa atttcagaat ttataaacaa tttcaagtta ttaatattaa ctttatttta
    15481 ataattaact attaattata ttttatactt tatgacaaaa taaatgctga aaactacaat
    15541 ttaactgaca tttgcgagtt tttactcgct aaaattaaat tgcagctttc agccacttta
    15601 gctgtgataa aatacacaaa tatcatattt aaaaaaggtc ttatttctca agcaacgctt
    15661 taactttatc taaaataaca ttggctactt cttctttttt catcttagga tactcagtaa
    15721 tatttccctc tacatctatt atttttacaa tattagtatc agctctaaaa ccagcacctt
    15781 ctttagttaa atcatttgcc acaataaaat ctaaattttt cttttttatt tttcctttgg
    15841 catgttctat aaggtcatta gtttcagctg caaatccaat tagtatctta tcttctttta
    15901 tttttcctat ttcataagca atgtcataat ttctacttag ttctattgat aaatcatcat
    15961 tcttcttttt aatttttttg tcagaataag tttttggttt ataatctgca actgctgcac
    16021 tttgaattac tattttattt tcacttaaat ttgatactac tgcttcatac aaatcttgtg
    16081 ctgactctat ttgaacaaat tttttaagat tttgtggaat agaaagattt gtaggacctg
    16141 atattaatgt tacatcagca cctctagcta tagcttctct tgctatagaa tatcccattt
    16201 taccagaaga cctattagtt aaatatctta ctgggtctat actctctaca gttggaccag
    16261 ctgtaactat catactttga ccttttaaat cttgctcttt agtaagatta gtcaaaactt
    16321 cctctactat tatatctgga ttagctagtt tacctgttcc aatatctcca catgcaagcc
    16381 ttccactttc cggttcaata aatttatatc caaagctctt taaagtttgt atattttttt
    16441 gaacaattgg attttcatac atattagtat tcatagctgg tgctataaga acctgtgctt
    16501 ttgttgccat aacagtagtt gtcaacatat cgtcagctat accatttgca atcttgccta
    16561 taacatttgc acttgctggc actattaaga ataaatctgc tttttttgct aatgatatat
    16621 gttcaacttc ccaagttttt ggttcttcaa acatatcttc tactacataa ttttgactca
    16681 gcgattgaaa tgtaagtggt ttaacaaatt ctgttgctga ttttgtcatt ataacatgga
    16741 tatttgcatt tagttttttt aacttactta caacatcaca agccttatat gcagctatac
    16801 cgccacttat gccaattaca acagttttat cttttagcat gaccttactc ctcttctgaa
    16861 atttgttggt gttgctcagc atgatgtcta gcttcttcta tctctatttc ctcttctgtc
    16921 aataatctat atgttatttt tccacttgca acttctttag ttgctacaca tacaggcttt
    16981 tccttagttt tatttgaaac atatggttct tctccatcaa ttaattttct tgctctcttt
    17041 gaaacagtcc ctactaaata gtatctgttg tctatttttt ctagtacctc attgatagat
    17101 ggttttaaca taattataat tcctccttaa atttctctat tataatattt ttatatctgc
    17161 taactttatt cttttcagat gatattatac cttctatttc tttagcagat gtttttacat
    17221 cttcattaaa tataaaataa tcataatcct taatcatttt aatttcttca tatgcacagc
    17281 taaatctctt ctctatttca gcttctgttt ctgtacctct tccaacaatt ctatttttta
    17341 attcttcaag tgatggtggt agtacaaata taaatactcc ctctgggcaa acttctttta
    17401 tttgttttgc tccttgcatt tcaatctcca gtaatacatc ttgtcctttt tctaaacatt
    17461 ccattattgc cgcttttgga gttccataaa aattatcata aatttgagca tactccaaaa
    17521 actcaccttt ttctatcatc tcttcaaact tttccttact tatgaagaaa taatttactc
    17581 catcaacttc tccagttctg ggttttcttg tagtagctga tacagaaagt tttattgtat
    17641 cattttcttt aagtagttct ttgcaaatag taccttttcc tgcacctgat ggtcctgata
    17701 caactagcaa taatcctttt ttcacaaaca tttaagcatt ccccttctaa tattgtattc
    17761 ttattctata ttttgtattt gttctcttat tttttccaat tcgcttttta cttctactac
    17821 taaattagtt atatttatat cagatgactt cgaacctata gtgttagttt ctctattcat
    17881 ctcttgtatt aagaaatcta tttttctacc tatagagtcg tctttaaata tagtattttt
    17941 aagttgccct atatgacttt taaatctaac tatttcttct gttatactgc ttttatctgc
    18001 atatattgca acttcttgtg ctaatctatt ctcatctatt atacttgggt catccagtaa
    18061 ttcacttatt ctcaaattca atttttctct ataatcttct acaacactac ttgagtattt
    18121 ttcaatctct tctatatgat tttttaataa atcacatctc atggcaatat cttcagctaa
    18181 ttttttacct tcttcacttc tcatttctct taatttgatt aatgcatctt caactgcttg
    18241 attcaacatt gaccacaata aatcttcatc ttcttccttt tcttctattt tcacaatatc
    18301 aggaaacttt gcaacattca taacgctaat atcatctata atatcaaatt tattttttat
    18361 ttcttttagt atgtctatat actgagatgc taatccctca tcaaaattta agtttacatc
    18421 ttctttgcct aataagtcaa actttatgta taaatctact cttcctcttt ttacataatt
    18481 ttttactaaa tttctaactt tatcctctaa aaatgaaatt tttcttggaa gacgtatgtt
    18541 tatatctgaa tacttatgat ttatcgtttt acactctact aaaaagtaat aattatcatc
    18601 cttgtattct cctcttccaa aaccagtcat acttatagcc attaattaaa cctccaaaat
    18661 accttcacat atttttactg ctggacctgt catataagag aaatctccta catctatttt
    18721 aactgttcca ccttgagacg ttacatttac actactttct accatattaa gtaaattgca
    18781 cactattgct gatgcagtca taccagtacc acaacctaaa gtatatccac aacctctttc
    18841 ccaagtataa acatgtatat tatacttatc ttctaccttt acaaaattta cattcgtttt
    18901 ttcaggaaat attttattat tttcaatctc ttttccatat ttacaaacat catctacatc
    18961 taattcatct actataacta ctgtatgagg aacccccatc aacatagaag taactttaag
    19021 ctccctatct aaaaccttta tactttcttg cacaaaacgt tctttatttg taagtacagg
    19081 aacgtcctta gctataaaac ttccttttcc catattgact cttatagagt ttatttctct
    19141 attggtaaga tttattttta tatcttttat accatctaat gtatctactg taaaactttc
    19201 ttttttaact atacaattat cataaacaaa tttacaaaaa catctaaggc catttccaca
    19261 catagctgct cttgaaccat cagaattata atataccatt tctacatctg caacttttga
    19321 atctttcaca actaacaatc catccgctcc tacagaaaat cttctatggc atactttttt
    19381 tgctaaagca gtataatcag atggatttat ctggtcgaat cttccatcta ttgctataaa
    19441 atcatttcct attccatgta gtttccaaaa tttcataagt atcgctcctt cgtaaattaa
    19501 cgcttaaact attataacat aaaaaaattc ccataaactt ataatttatg ggaaaagttt
    19561 tgtaatgaca actataattt gaggatgtga gggagagttg ccattacaat tagggtaatt
    19621 atattatgtt tttaagctag ttctttctat gtttatatat taatatttct atatgaattt
    19681 tatgtatgtt ttatttaaac tgtctatgaa ttttttaatt aaacatctgg taactagcta
    19741 taatccttct agtagatatc tattaacata cacctattaa ttctttaagt gtttttaaaa
    19801 catagtctaa atcttcctta gtaatatcta catgagttac aaatctatat tcaccatttt
    19861 ccattttatt aatttttata tttctttcaa aaaattcttt tattaaaaca tcctctttta
    19921 taatatcttc actcatctta aaaaatacca tacttatatc tggattaaca ttgtttactt
    19981 caatgccatc aattttattt aattcacaag ctaaatattt tgcattttca tggtcttcat
    20041 tcaatcttaa agtcattttt tcaatggcaa ttataccagc tgctgcaact atacctactt
    20101 gtctcattcc cccacccata actttttgct ttcttctagc ttttgctata aattctttac
    20161 ttccagcaag tatagaaccc attggtgcag ctaaaccttt tgacacacag aacataacac
    20221 tatcacaaca ctttgctatt tctttagctt ctacacccaa agttaatgct gcgttaaata
    20281 atcttgctcc atctaaatgt actggtaagt tatgtttctc agctattttt ttaatttctc
    20341 ttaaattatc aagactcaca actgttccac ctgaatatgc attttctaca catataagcc
    20401 ctgtctgtgg ttcatgtatg tcatctcttc taattgcctt ttcaacaagt tcaggattta
    20461 gagctccact ttcgtcttca tctatagttc taagctgaac tccagctatt acagcaggtg
    20521 ccccaacctc atgagtcaca atgtgataac ctttaccaat aattatttct tgccctctta
    20581 ggcaatgagt aaatagagct aattgattcc caaaagttcc acttggaagg aaaatagcat
    20641 cttcttttcc aactttagct gctgctaatt cttcaagttt atttacagta gggtcatctc
    20701 taaagattga atctccaaca ggagcctttg ccatagcttc tctcatttcg tcagtaggca
    20761 tagtaacagt atcacttctt aaatcgataa atctcatttt ttcaaccttc tttcatattt
    20821 atatactata gaaccttaaa attgattttt tctgtaaagt tcatatactt tcatagctta
    20881 tactctacac aataattata ctatatttac tttatattta atctacttta aattattaat
    20941 tttaaaaata aagtttcctc tctaataaat ataaataatt atacaattta aatattaatc
    21001 tctattgttt aaattccccc tagtcacaaa gcgtatatta tgtgtataat taatttactg
    21061 actcattttg gtcaaagaaa ggggtgctat aaatggcatt agatggatta gttatacatt
    21121 caatagtcga tgaattatca tcaaaactta caggtggaaa aatagataag atacatcaac
    21181 ctgaagatga tgaggtaatt tttaatataa gaaataataa agaaaatttt agattggttt
    21241 taagtgcaag tgcctcaaat cctagagttt atcttacaag taattatcaa aaagaaaacc
    21301 ctctaaaagc gcctatgttt tgtatgttac ttagaaaata catacaaggt ggaaatatag
    21361 tagaaatttc tcaaataggt tttgaaagaa taataaaaat aagcgttgaa tctttagatg
    21421 aattaaaaga aaagacagtt aaaaatatta tgattgaaat tatgggaaga catagcaaca
    21481 taataataac tcatggtgaa gaaaataaaa ttatagattc tataaaaaga gtccctttta
    21541 gcataagtag agttcgtcaa gttttacctg gtcatgatta ttcattacca ccagaacaaa
    21601 acaaactcaa ccctcttgat gatatatcta aggatttgtt tattaaaaac ctagaggaat
    21661 tggaaggacc tatctttaag tctatatatt ctagatttct aggtataagc cctattatag
    21721 ctaaagaaat ttgctacaga gcaggtgtaa atcaaaatgc tatcataaag gatatatctg
    21781 atgaacaatt tgattcttta cacaaagtat tttgtaattt attcaatgat ataaattcta
    21841 acaaatactc tccttgcatt attatagata aaaaggtgga taaggtagtt gatttcagtt
    21901 gtataaacct tacattattt agcgatttat catatataaa taaggatagt atgtctcgta
    21961 ttctggaaga tttctataga actaaggata ttaaagatag aattaatcaa cgttcatctg
    22021 atttaaagaa gagtatatct gttaagcttg atagacttta taataaactt aaaaaacaag
    22081 aagaagaatt atcagaatcc gaaaatgcag acatttataa gataaaagga gaattgatta
    22141 cttcatatat ttatatggta gaaaaaggta tggaaagtat tgaagttgct aacttctatg
    22201 atgaaaattg taatgatgta acaatagaat taaataaaaa cttgacacca tctgaaaatg
    22261 ctcaaaaata ctttaaaaag tataacaaaa tgaaacatgc taaagtcgag atatctcatc
    22321 aaatttcctt aaataaggaa gaaatagatt acttagaaaa cataatttta agtattgaaa
    22381 actgtgaaaa tttagctgaa ttacaagata taaaagaaga acttgctaaa gttggataca
    22441 tcaagactca aaagaaaaac agtaaaaagg atactatccc atctacaaaa cctcatgaat
    22501 ttgtgtcttc tgatggattt aaaatattgg ttggtaaaaa caataagcaa aatgactatc
    22561 ttacactaag acttgctgat aatgatgact tatggatgca tacaaagaat attcctggtt
    22621 ctcatgtaat aataaagtgt gctggtaagg aagtccctga taatactgta tttgaaggag
    22681 ctatgctagc agcattcttt agtaagtcaa aactttcttc tcaggtgcct gtagactata
    22741 ctaagagaaa aaatgtgaaa aaacctagtg gttctaaacc aggtatggtt atttatgaaa
    22801 ctaacagtac tatttatgtt actcctgaag aagaaacagt agccaagctt aaggttaaat
    22861 ctgaataaat tctgcactaa atacaaaata aatgttagac aactacacat tatcattcta
    22921 aataaaaata gtggccttct tataaagtac aataataggg ccactttcta attagcttac
    22981 ttttaatttt ctaacaaaat acttttctgt tttaataact atacttatat tcccaacaaa
    23041 tattttcagt tttcttatat agatgtaatt aaaaagttaa cactaaaagc tattttttaa
    23101 tttagtgatt tgttttagta attcattata ttctgattca tacaattctt tttttagatt
    23161 atctttttct atagataaca tagatataac agttgtaagt ctattttcta atactagaag
    23221 attttctttt ttgatttggt tttctctact aggagttttt ttatttctgc taattatata
    23281 ttcgtcataa ttacaatcaa actcccttat tttagcatct tttatctcta taatatagtt
    23341 acaaatatgt gatacaaata ctctatcatg agacactata agcatagttt tatcagtatt
    23401 tatcagtgcc ttttccagtg cttccataga ttttatatct aagtaatttg ttggttcatc
    23461 aaatactaaa aaattattat cttccaatat tattttacat agtgctattt ttaccttttc
    23521 tccaccacta agtactttta cttttttgta gacatcatca cctttaaacc caaataggct
    23581 taagtttatc cttataaaag attcatcaaa tgaactatta actttagtat tgtatagaac
    23641 actctttttc tcatctaata aactttgatt ttggtcaaaa taacctactt ttaccttgtt
    23701 atttattttt atattgtcat ttttatcagc caatatttct tttatcagag tactttttcc
    23761 acacccatta tcacctaata atgctatctt tttacctctt tttatcttaa aggaaacatt
    23821 atctaacagg agcttatttt ctaactttag agtcatatct tttatctcta ctagattttt
    23881 gctaattatc tccataccat cttgaatctt aatgttcatt tctttagaaa ctttaggttt
    23941 attctttacc tcaagtttat caattctgct ttttatagcc ttcacatttg agtccaactt
    24001 tttcttatta gtctgaccac ccattttgtg caacctagct tctgaattac ccattctttt
    24061 tggtgttttt cttatgccct cacttaaagc ttttttatat aaaagagctt tttcaagcct
    24121 ttttttctct ttaacatatt cttgatactc aaaatcagct ctttttactt cttcatcttt
    24181 ttgcattaaa taatcagtgt aattgccttt gtaagctttt agttttccat cttctagttc
    24241 taatatagtt gtacataact catccagaaa acgtctatca tgagatatta ataataatgc
    24301 tccctcatgc cttttaaaca tatcttccaa aaccccaatg ctttttttat ctaagtttga
    24361 agttggctca tcagctatta tgatattttt cttattactc agcgcatctg ctatttttaa
    24421 cttaaccttt tcccctcctg ataagtgttc ttcaaattta tctggagcat ttaaaagact
    24481 cttctcctta ctatgaccac atgtttcaat attattttca ctctgactta tataagaata
    24541 gctttctgta aggtaagtat atccttcatc aatttctatt tctcccaata ttgcttttaa
    24601 taatgttgtt tttccttgac catttgaacc aactagacct attttgtcat tttctaatat
    24661 ttcaagttta tctatatcca aaattaattt atctgcataa tatttcttta aattctctac
    24721 ttttactaac aacataaaaa atccctcctt aacacactta aatataagga gagattctat
    24781 aaataggcat aacaaataaa cgtatagact ataatctact ctccttaatt taagcattgc
    24841 aaataaagcc accaaaatag gcttttcaaa aattacaata ctttaaatta taaaaaatag
    24901 attatattct cattgtccta gttaccttgc cctttctttc atttattttt aatcattata
    24961 tcaacattaa ttacaaatgt ctatagaaaa ttaactaatt ttagttattc aatatagaac
    25021 ttattcttta aatttattct tcttcaactt taaagtcctg attatttaaa attctgttta
    25081 atacaattcc aacaattgca gctaaactaa gaccagttat ctttactgta cttgttatag
    25141 ggattccaac agaaatacct ttattagata aatatgttgt tccaagacct attaataata
    25201 taactgctat gattaatata tttattttac tttctacaca agaactgtcc cttatagttt
    25261 ttaatcctac ataagttatc atcgaaaata gcattatact aattccaccc ataactgaac
    25321 ctggtatact ttgaagaaat ccaccaaact tgcctacaca tgcaagcaat atagcaaata
    25381 ttgctgtacg tctaagtatt gaagggtcat agtttttagt tatagcaagt actgctgtat
    25441 tttctccata agttgtattg gctggtcctc ctaaacaccc tgcaactata gtcgcaaatc
    25501 catccccaag taatgttcta tttaatccgg gattttctat aaagttttta cctactacag
    25561 caccattagt agtcatatct cctatatgtt ccataaatac agctaataca actggagata
    25621 taatcacaat tgctcctaaa ctgaacttag gaactgtaaa gttaggtatt gcaaataaac
    25681 ttgcttctgt aatagtagtt atatctacta atcttaatat caaacagatt atatacccag
    25741 aaaaaactgc tattaatatt cctaattgtt ttataaatcc tctaccaaac ttattggtta
    25801 aaattgctat tgctaaagtt ataaatgcta ttacaaaatt ggctgaagcc atactaaaag
    25861 ctgttggcaa taaatttaat cctataacta ctatcatagc tcctgtaact tgtgcaggaa
    25921 aatataattt aattttattt acaccaacta cttttactat aatcgacatt ataatataaa
    25981 ttaatcctgc tactattata ccaccttgag catatgctaa atctccacca tacgcctctt
    26041 tagctgctag tataactggt ataaacgcaa aacttgaacc taaaaaggca ggtacttttc
    26101 cttctgtaca aaaatgaaat atcaatgtac caacaccagc acagaaaatt gcaactgatg
    26161 gattaaaacc tgtcaaaatg ggaactaata ctgtcgctcc aaacatggct aatagatgtt
    26221 gtaaagacat tatcgttttt ttcataaaaa cctccaaaat tattatatat aaataaaccc
    26281 tctgtttaat taatatcttt taattaatta tcattcccta gattctattt tttaacctct
    26341 atatacttat tatataattt atcattattt tacattttac gacatcaaaa actcaaataa
    26401 aggagaataa aaactacatt aagactcaca tccataaaat tataatattt attttgtgca
    26461 atctatgtaa gctttatcct cctccctgac tattcaatgc taagcttttt atataatact
    26521 taaaaataat tactctttga ttgtaactga atcttctcca tcaatttcta ataaactgac
    26581 agatataatt tcatgtctag aagtaggtac attttttcct acataatctg ctcttatagg
    26641 caactctcta tgccctctgt ccactagcac tgctaattgt attgatttag gtcttcctat
    26701 atctataata gcatctagtg aagctctcac agttcttcca gtgtataaaa catcatcaac
    26761 taaaactact gtcttatcat ttacattaaa atctaaataa gttcctttaa ctacaggttc
    26821 aacatgaatt ttttccaaat catctctata caaagttata tcaatatctc ctgtatctac
    26881 ttttgttcct tctatttgtt ctattttctt agaaattcta tttgcaattg gcacacctct
    26941 agtctttatt ccaactaaaa ctagattttc tacaccttta tttctttcaa ttatttcatg
    27001 acttattcta gtaattgctc ttgctattgc cttttcatcc attaattgag ctttttctac
    27061 catatcataa ttattgtcaa agatataata tatctatttg acaaatctac tcctttcttt
    27121 taatttttta taaatttatt tttatttaaa atttcaattt aaacaacaaa aaaacttctc
    27181 atcacaagac aagaagctct tatataaaaa atatacagtg caatttagca attgtcttac
    27241 gatatctctg tatcgtttaa agataatttt ttaatctatc aaatcaaatt atatatttat
    27301 atttcaaatt tttcaagctt ttttaaacaa aatactttaa tataagatat tttatttaaa
    27361 tttcactaaa tttatttact tatataaaaa caaaaaataa tttataagta ttatacaaat
    27421 ggttatttta tctttttaat aacttcctta aaatactcag gtaattctga attaaattcg
    27481 atatattcct tagtagtagg atgtataaat cccaacttct tagcgtgcaa agtttgtcct
    27541 tttaatttaa atttagtttc ttttggacca tatacataat cacctaaaag tgggtgattt
    27601 atagacaaag catgaactct tatttgatga gttctaccag tttcaagcct agctctcata
    27661 tgtgtaaact tatcaaatct ttctacaact tcaaagtgag tgattgcatt ttttccatct
    27721 tttactacag ccatttttaa tctatcctta ggatttctcc ctataggttt atcaacagtt
    27781 attttatctt ctttaaccac accatagcat ataaattcat actccctagt tatagtatgt
    27841 tcctttaact gttctgctag aaaattatgt gcataattgt tcttagctat cataagaaga
    27901 ccagaagtat ctttgtctat tctatgaact ataccaggtc taataacgcc atttattgat
    27961 gacaacttat ctttacaatg atataaaatc ccgtttacta acgtattttc atagtttcca
    28021 ggagcaggat ggacaaccat atcctgaggt ttatttatta ttaagacatc atcatcttca
    28081 tatacaatat ctattggaat atcttgaggt aaaacttcta atactttagg ttctggtatc
    28141 tctataacaa tattatcttc ctctttaacc agatatctag ctttttctac tttattatta
    28201 acctttactt ttccatcttt tataattttt tgtatataac ttcttgacat atcacctaat
    28261 tgttctgcta gataaatatc aagtctaact tcttcttcct cttcaagtac taaaaactct
    28321 tttacttcat ccattatatc acctactttt actttcaaaa aataaaacat atatacataa
    28381 aaacacagtt cctacaacta caaatacatc agctatattg aatacatatt cccatataat
    28441 tctaaagtcg aagtaatcta ctacaaaacc taatcgtact ctatcaatta gatttcccaa
    28501 tgcaccagat ataattaata taattcccaa ccttccaaat atatgtactt tccttgtatt
    28561 aagatagtat agtccaaata ctgttgcaag taatgcaaca attataaata tccattgatt
    28621 attttgtaat aatccaaatg ctgcacctct attttcgaca taagttaaat gaaatacatt
    28681 atttattatt ggtattgttg atacatccac caaattattc aatacccata ttttagacag
    28741 ttggtctaaa cctatgagta gaattattat taatatatat agcaatgatt tttcccccta
    28801 taaattattt aaaaaccaat tttatttgaa gcacactatt attatacaaa aaaaatgctc
    28861 taaagagcaa ctttattaaa attgtatttt cttaataaag ctagaacaaa atttaaaata
    28921 gtactacttt ttttatattg tagatttcta catatttaaa atcatatcat tatgtataaa
    28981 aaatttaaaa ataccatact aatcaatatt ttttgtgtat tttatagatt aaagattaat
    29041 gatgtctgta atttaaactt acaatcacca ctaatcttca aacaaatatt tttacttttg
    29101 cacttgctta tttttatcta aatgttgtat aagttcagat actgttacga atttatatcc
    29161 tctctctttt aatttaggaa ttactacttc taaagcttgt atagtttgtg atttatcatt
    29221 tcttttagtg ttataatcat gtaaaagtat tatattacca ttttggacct ttgtaaggat
    29281 agtatttata attgcatcta ctccagggtt agaccaatct ctagggtcta agtttgacca
    29341 aagaattata ttcatgcctt tagaaactat aatatcacag acacttttac tcatggctct
    29401 atatggaggt ctaaatatct ttggttctac tcctattaca ctttttataa tattttgcgt
    29461 atctgttatt tctttttcaa cactactata actatttttt gcaacattta tatgtgtaaa
    29521 tgtatgattc cctatttcat gccccccatc atattgtctt tttaataatt ctttgttata
    29581 ttctactttt tctccaacta caaaaaaagt tgcttttaca tcatttttct ttaatatatc
    29641 aagtacttgt ggtgtaaaat cctcatctgg accatcatca aaagtcaatg ctaaaatttt
    29701 ttcatcctca tttccttttt ttattattac atcttcataa tcgtctttta tattgtcatt
    29761 taaactatat gcttcttttg aactatcttg attatgtgta ttatgactat atgtatatac
    29821 acctactata gataataaac atatacatat accccatatt attttcttca tgtcattacc
    29881 tcttttctaa ttcattctag caatatattt tataatgtca gttttttaat ctctcaatat
    29941 tccattttta tttaaatcag ttaaatttgt taggtcttct gaataaaagt tagaatcttc
    30001 tacatcaggg ttttgcattg catcacctaa taaattattt tctttatttg cacaatcatt
    30061 acataaactt atatctggca atatatccaa tctttctaaa tctatttgat tatgacataa
    30121 atcacaaatt ccatatgttc cattctctat tttagataat gctaagtcta tttgatacaa
    30181 tcttccctct tcatgattta ttagactgtt ttgcatattt tgcatatata aatctgttcc
    30241 catgtctcct atatgattat cataactaga taattctcct gatgaatact tttcacttgt
    30301 atgtttagtt gtatctccaa ataaagtatt atctttcata tcctctacta aattagttaa
    30361 attttctctt tctttcaata atttatcttt atatttttta gtatccattt ttaacacctc
    30421 taattttaat atttacatca taaaaatagt atgtggaaaa gtaaattaaa catacaataa
    30481 aaataagatt tgattcgaaa aatagaatgt ctcaaaatga aatttttagt tcatttaacc
    30541 ctctttttta tataaaatca aatatatttt tatcctttca gcaataaaaa agagacttat
    30601 ctctattttg agatagcctc ttttttgaac ataatttaaa tacaattttt tgatttttat
    30661 agttattatt ttactaactt gccaatttat gattattttg ttccttaata tgctttgctt
    30721 ttttaaagaa taaaagacca agaattattg ctacaataac acctattcca ttagatatat
    30781 taactggtag tctaaatcct tcttttgctt gcattatata actaaatgtt actacagtca
    30841 taaaaagtgc tggtaatgta gttatataat ggtttttatt tgctttgact aaatatgcag
    30901 aaccagtcca caacattatc attgcaagtg tttgatttgc ccaagagaaa tatctccaaa
    30961 ttatattaaa atctataaat gtaagagcaa caccaactgc gaataatggt aaagctatta
    31021 aaaatctatt tttgactgca tcttgattat aattcattgc atctgctatt gtcagcctag
    31081 cacttctaaa tgctgtatct ccagaagtta taggacatgc cacaactcca agtatagcta
    31141 aagctcctcc aataggaccc attaatccaa cagatactgt atttactact gttgctgctc
    31201 caccatcatt aaatatcaca ttaagttgag gtatgccatg gaaatatgac atggctgctg
    31261 ctgcccaaac taaagctatt ataccttctg caaccattga cccataaaat actggtcttg
    31321 cctcactctc tttctcaaca catctcgcca taagtggtga ttgagttgca tgaaaacctg
    31381 atattgctcc acatgctatt gttataaata agtatgggaa taaaggtgtt ccatttggat
    31441 tcatattttg taaatttata tttggtatgt tatacccctt tattatcaat cctccagcta
    31501 cacctactgc cataattaat aatgctgctc caaataaagg atatatttta ccaatcaatt
    31561 tatctattgg taaaaccgta gccataatat aataaagtat tatcactcca acccatattt
    31621 gtgcgtttac acctgtcaat gtctttaata atcctgctgg acctgttaca aatacaactc
    31681 caaccaatac taaaagaata acactaaata ttctcattgc tatttttgca ccatttccta
    31741 gataaagtcc taccaactct gatgcagatg tacctttgtt tttcattgat agatatcctg
    31801 aagcaaaatc gtgtactcca ccagcaaaga ttgttccaaa cacaatccat aaaaatgctg
    31861 atggtccaaa taatgctcct tgtatagctc caaatatcgg acctaaccct gctatattta
    31921 gaaactgaat taaaaagatt ctcttccatt tcattggcac ataatctact ccatccctac
    31981 aagctatagc tggagtttga tttttgtcat tggttccaaa aaccttttct acaaaagtac
    32041 catagacaaa ataacctact ataagtacta ctattgaacc taaaaagctt accataaatt
    32101 catcccctta gtttttatat aattgcttta taaattttta tgagtttaag aaaactattt
    32161 ccagttcaaa tagtaatact tttttatgct aatataaata ttaattacat taagtgcata
    32221 tttaagtaca tgaaatgact ttatatatgc attaacagcc taaattcttt tactttgctt
    32281 ctacttacag ttacttcata atcactattt tttaatttta atatgtatgt attattaaac
    32341 catggtataa tttcttttac tttggttaag tttacgatat aagacctatg tgttctaaaa
    32401 aatgttttat catttataag attttcgact tctgatatgc cttcttttaa tataaacttt
    32461 tctttctcag tatatataaa tgtctgcctt tcattagctt cacagtaata tatatcatca
    32521 atatctatta caactaattt atcacctttc caaaggctaa ttttatgtgt tatttcttct
    32581 atctcctgat ttactgcttc cttcttatat ttgtataaat tactatttac attagatagt
    32641 tcaatatcac tcatctcact tttttctaat ttattcagca tagaaataat tctctcttca
    32701 gaatatggtt tcaatatata atcaaataca tccaaagaaa aagcatctac tgcataactt
    32761 tcatatgctg ttataaaaac aattttaggt cttgatttaa actgatttaa tgtttttgca
    32821 agtagcattc catcaagatg aggtatattt atatctaaaa aaattacatc tattttattt
    32881 tcctgaataa agtctaacac ctctatacca ttggtaaatt cacttactac ctcgattcca
    32941 cttttatttt caataaaata tctcaattcc tttcttgctg gaaattcatc ttccactatt
    33001 atagctctca tacttctact cctttacata aaatactatc aaagtcccat tatctattct
    33061 tcttatatta agccctcttc catacatcag tttaagcctt aaatgtacat tataaagccc
    33121 aatcttattt tctggcatat tatcttgata tacattattt ataatttcct cacttatacc
    33181 tataccatta tcctctattg atattctcac agtattttct aatgaatacg gtaacttttt
    33241 tatggatatt ttcactacac cagctctacc actttctaaa ataccatgta ttattgcatt
    33301 ttccactaat ggttgtataa tcaaacttgg aatctttata tttacatctt ctatatcata
    33361 agatacagtt agtaattctc caaacctagc tttttctatc tctacaaaag atttaacttg
    33421 ttcaatctct ttatttatat caattaagtt atcactatat tcaagattat atcttagata
    33481 agttgataaa tttattatta actctctagc cttatctgga ctaaatctta taaatgaagc
    33541 tattgtgttt agggaattaa acaaaaaatg tggattaatt tgtctttgaa gtgcttttat
    33601 ttctgcttta tttctcgctt ctatatcttt tttatctttc tcaatcccct ctactataga
    33661 tataacaaat cctattccaa tctgcccaac tattaaaggt aaatatattc caccgattat
    33721 ttgaattgct aaagaatgtg gatatgatat taagtatata agtaatatag taaaactttc
    33781 agaaatcatg cctaccaata ttccatacat tactctatgt tgttttggta tcctcttata
    33841 tagaaatcct gataatacac ctgctagtat acttgataaa agacatggaa cagatgttat
    33901 ccccccaata tccataaaat atctatgaat ccctgaaaaa actcctgctg taatacctac
    33961 catcggacca aataaaatgc cacctgatac tatagatatt attctagtgt ttactattga
    34021 ccccatataa tttataccac tataagttcc aaatatggct aaaaaagtaa aaactaatgc
    34081 tatacagacc aagtcattaa aactatattc ttccttttga aatatctgct taaatatttt
    34141 taactttgtt attagaagaa acaatactac aataaggctt gtcttttcta ttaatgcgat
    34201 taaaattgat gttttcataa tcccccttta aaaaataaat ttttacacac tctaaattta
    34261 ttatggttgt tataaattac atatttgaag taatcctatc acaaaacttt ccacatttaa
    34321 tcttttaatt aaataagaaa tagttgtact tctattaaca actaatacta gctagcataa
    34381 gcttgtaata acttgtagtt attattaact ttacaattct agtatttaat tttatacttt
    34441 agaaatctct tttcttagaa ataatacttt cgaatatcat ataatacaat attatgtaga
    34501 ttcttactca tacaacatat ttctttaaaa attttatact attctttgtt caaatatctc
    34561 atttgattta attgtgttaa acacacatta tcatctctct gttatatatt tattatatag
    34621 ccgtatatcg ataaagtaaa taaatcccat atttaaaata atatgtttga caataaatta
    34681 ttataatgta tatttaccat aataatttgt caaccttgaa agttacttct ataattattg
    34741 ttaaataatt cttctaaaaa aaatacctat aaattttatt ttctgaaata catagttata
    34801 actattttta tcacgtataa gaataaaaat tccagaaaat ttttattatc taagttaata
    34861 taaaacatat tatttaatat aaataaattt tttataataa tatattgatt taatttactt
    34921 tattattgta aactataagt ataagatata ctatataaac aagcataaat ataccttaat
    34981 tctaactatc cttaatctta tttatctcct agtgttattt tatgtatttt ctataaaata
    35041 cttttgtttt tttacttttg aattttttat aggagggtat ttagtggata tattaatctt
    35101 tgataatgat gtttgttttg gaatgaaact aaaagaaaaa ataaataata ttttaataaa
    35161 agaaggtttt gataatgatg ttgtaagatt atatcataat gcaaatttgt tattaaaaga
    35221 gcttactgaa aaaaataaag taagaatata ttttatagtt gtagacgcaa aatataagat
    35281 aagtaatgaa ttatgtgatg gattatggat agcacaaaaa attagagaat cagattatat
    35341 tagtccaatc atatttctta caaatcatat agaaatgatt ttagggatct tcgattatag
    35401 gttagaagtt atggacttta tactaaaaca tgatatggaa attgctgaaa gtaaaataaa
    35461 agcttgtatt aaaattgctc acaaaagata cattaaagaa aaaaattatc gctctaattt
    35521 ttttactatc tattcagatt tctcactatg gaaaatttca tttgatgaag ttatatattt
    35581 tgaaacaagc actattccac ataaaataaa attagtgact acttctagaa tatttgaatt
    35641 ctataaaagt ttaaagtctt taccagattt agatgcatgc tttatccgtg tacataaatc
    35701 ttttgtagtt aataaatatc atattgtttc tctcgaccta aagaaaaata atattaaaat
    35761 gagtaatggc catatatgtc gtatatctaa tacatataga aatattttaa agaatattat
    35821 taaaacataa taaatagaaa aaggagatgt ctcaagataa aaatttgaac catctctttt
    35881 ttatacaaaa agagtaatcc ctaagaatcc tctatataat aatcatattg tgaaaaaaca
    35941 catactgact atatcatata taactactat tagatattat aacaattgtt cctagattat
    36001 gattcgataa gatagctcat taaatcataa aagtacgaaa tagtctcttt aaaatattca
    36061 gttgttattt tgtactgaca tatcatataa atacatattt ttatgatata tacctacata
    36121 ttttatgaaa tttatataaa aaattcttat ttagattata taatctaaat aaattaaaat
    36181 tcaaaagtta actaaactaa tatttgtagg gagaataaat gaaaaaattt aggaaacata
    36241 aaagtattag taattgtata tctatattgt tgatattata tctaacttta ggtagtttgt
    36301 tacctaataa catttatgca caagatttac aaagctatag tggaaaagtt tgtaatacta
    36361 cttacaaggc tcctatagaa agatcagaag gattttttta aagataaaga aaaggctaaa
    36421 gaatgagaaa gaaaagatca aaaacttgaa aaatctgaaa aagaagtatt aggatcatat
    36481 aaaaaagatt ctatagagat aagcaaatat tctcagacaa gaaattattt ttatgattat
    36541 caaatagaag caaattcttg agaaaaagaa tatagagaac ttcgaaatgc tatatcaaaa
    36601 aataaaatag ataaacctat gtatgtatat tattttgaat ctccagaaaa atttgcattt
    36661 aataaagtaa taagaacaaa aaatcaaaac gaaatttcat tagaaaaatt taatgagttt
    36721 aaagaaacta tacaagacaa attattacca tacaacagat aattcaactg ctgttcaaaa
    36781 tagcaatgga taatcatgaa atactggatt aagtataaac aaaggagaat ctgcatatat
    36841 aaatgcaaat attagatact acaacacagg tactgcacct atgtacaaag tgacaccaac
    36901 aacaaattta gtgttagatg gagatgcatt atcaactatc aaagcacaag aaaatcaaat
    36961 tggcaataat ctatctcctg gaaatactta tctcaaaaaa ggattttcac ctatggctct
    37021 taacacaatg tatcaattta gttctagact gattcctata aattataatt aattaaaaaa
    37081 attagatgat ggaaagcaaa ttaaattaga aacaacacaa gtaagtggaa attttggtac
    37141 aaaaaatggt tctggacaaa tagtaacaga atgaaatagt tggtaagacg atataggtca
    37201 aattgacagt atttctgtat ctattatatt agatacagaa aatgaatctt acaaaagaag
    37261 aattactgct aaaagtttac aggtcccaga agataaaaca cctgaactta caattggaga
    37321 agcaattgaa aaaacttttg gcactactaa aaaagatggt ttgttatatt ttaataatat
    37381 accaatagat gaaagttgtg ttgaactcat atttgatgat aatataggca ataagattaa
    37441 agacagttta aaaactttgt ctgataaaca aatatgtaat gttaaacttg aaagaggaat
    37501 gaatatactt ataaaaacac caacttactt tactaatttt gatgattaca ataattaccc
    37561 tagtatatgg agtaatgtta atactacaaa tcaagatggt ttaaaaggct cagcaaatag
    37621 attaaatggt gagacgaaga ttaaaatacc tatgtctgaa ctaaaacctt ataaacgtta
    37681 tgtttttagt aaaattcaaa aaatccttta acatataatt caataattgt aaatataaaa
    37741 gtaaaagaag aaaaaacgga ttatttggta ctagaacaag gatatacaaa atttagttat
    37801 gaatttgaaa ctactgaaaa agattcttct aatataaata tagcattaat tgatagtgat
    37861 acaatatact tagataactt atctattaca gagctaaata gtactcctga aatacttgat
    37921 gaaccagaag ttaaaattcc aactgttcaa gaaataatag ttacacataa aatatattct
    37981 gcagatttta aatttaatcc aagtacaata aaggcttata taaatggtat gtattttaca
    38041 ccaacataaa ctaataaaga agctctcgat tatgtccaaa aatatagagt tgaagctact
    38101 ttacaatatt ttggatttaa agatattgaa actaaagata aagaattgcg taattattta
    38161 ggagatacaa atcaacctaa aactgattgt gttaatctta ggagttattt tacaggtgga
    38221 gaaaatatta tgacatacaa gaaattaaga atatatacaa ttactcaaga tgatagagag
    38281 ttattggttc ttagtgttga ttagtatcaa atgatttaaa tttatcccca caatacaata
    38341 tgtatttacc ttataaagta ttaaaaaatt aactttataa ggtatttttt atttaaatat
    38401 tatcttcttc taatatattc ttttttagaa ctatattgta ttaaaaagat aattatctgt
    38461 atcatatcac ctatatataa acataaattc atttaattat ataaatttaa aaaatatttt
    38521 tttgatatat tattgacaat tttcattata agagttaaaa ttaactcata aattacatat
    38581 tgggtataaa atacaatgta tgttagaagt tgtttcagaa ggctatggtt ttctgatttt
    38641 tttatgctca gtagtgatat gcaaaaaaga caaagttgac atcagttaac ttttaccttt
    38701 attctacttt ccccaaagta agaataatct aacccctttg agatgagcaa aagctcatct
    38761 ttttttatta tcaaaagatg ctgtctcaaa atagagataa tcctcttttt cattgttgaa
    38821 atgattaaaa tatattttat ttcatacaaa aaagagtgcc tcatgaacaa aagttcactt
    38881 tgagactctc tctttcatat catatacctt tttaataact ttaaaattta tttatcaagt
    38941 aaagatagct aataattagt atcttctctc tataaatcca acttttttat aaacttttct
    39001 aagagttttt ctagcttgtt tttcggcttt ttctgctccc atactatata ttttttctaa
    39061 ataatcttta ttattaagaa ggtcaacata tttttctctt ataggtctta aagcttctga
    39121 tactacttca gccacatctt ctttaaatat gccataaccc tttccttcat acatgtttac
    39181 aatctcttct acactctttt tacttaaatt agaatatata tcaattagat ttttaatacc
    39241 tggttgttca tcattgtatt ttacaacacc taaagaatca gtaacacttc tttttatctt
    39301 tctctttata gaatctgaat catctgctaa tagtataaat gcattttcat ttgaatcgga
    39361 tttactcatt tttttagttg gctcttgcaa actcatcact cttgctccac cttttgggta
    39421 gtatccttct ggaactacaa aagtaggtga aaatctatta ttaaatctat ttgctaaatc
    39481 acgagctaat tctaaatgtt gtttttggtc atctccaact ggaactaggt cagtttgata
    39541 caacaatatg tcagcagcca taagaactgg atatgtgaat aaacctgcat ttagatttgc
    39601 ttcactcttt tgtgatttat ctttgaattg agtcattcta cttaattcac ccatataagt
    39661 catagtattc aatacccaca taagttcaac atgctctttg acatgtgatt gtataaatat
    39721 agtatttttt tctgggtcta atccacaagc tatatattga gcaagtaatt ctatagtatt
    39781 ggctcttaaa actttagggt cttgaggtac tgttattgca tgtaaatcaa ctatactata
    39841 ataacaatca taattgtctt gaagttcagt ccagtttttt atagctccta aataatttcc
    39901 taaagtcatt ttgcctgatg gctgtgctcc actaaatata actttttttt cactcatttt
    39961 tttgtacctc cttatatatt tatattgatt ttaacatatt taaaactatg tctttagagt
    40021 tattggcagc atcatgtaca aatacatcat aagtaacatc agcacttcca tctgccttat
    40081 cagacattgc tcttattatt acaaatggag tattatttaa atagcataca tgagctatag
    40141 ctccaccttc catttctcca caatatccac caaaatcatt tactaattct tcttttaatt
    40201 ctttagaatt tataaattta tctcctgtaa ctactcttcc ttttaatact ttatgagtct
    40261 ttacttcttc cacagaagat ttgtaagcag catctataag tctttcatct gctttaaata
    40321 cagaagtctt cattcttggt ataactccct tagggtctcc aaatgctgta gtgtctacat
    40381 catactgtat agcatcagtt gatattacta tatcattaac atcaagtttt tcgtttaaag
    40441 ctcctgcaac acctgtatta acaatagcat caaccttaaa ttcgcttatt agtatctggg
    40501 cacaaagagc agagttaacc ttacctatgc cacactttac taatactaca ttcttacctt
    40561 ccaaaattcc cttataaaat tctaagctag ctttttttat agtctctcta atatccatta
    40621 aatcaactaa aatactaact tcttcatcca ttgcacctat aattcctatt acgttcattt
    40681 ttcctcctaa attttctata ttaaaaaatc cgtcctaaat caataggacg gatatatttt
    40741 ccgtggtacc acctaaattt atatacactc aaaattgaat atatatatct taatatatgc
    40801 tataacgtgc atacacgata tcaaatactc tgtaatctta aattacattt cattttactc
    40861 ctcaaagacc cattcaataa atacttttta ttaagttctc agcatcctta attctctgtg
    40921 caaaaatata tttatttact atttcttatc tcaggattta atttattaat ttctttattt
    40981 tataatattc cttacactat aaattgtcaa ctatatatta taatatccaa aagaaatttt
    41041 taaaatacat tttatttagc tgttttcttt tcatatctat tccataacca tagaccagat
    41101 aatataacta gaagacctcc accaatcatc tctatctcat atataacatt ttcagcaaat
    41161 gtaggcataa ctggtgctgc agataataat atacccacta cagttacaac taaaaccatt
    41221 tttgctaaac ctaggcaagt acttgttgat tttgccatag tataaggtct aatttcatct
    41281 ggtctctctt ttcttagttt aatataagaa gcatataaca atacatatgg gaataatgca
    41341 gttaatgctg tcatagttac aagaacattg tatatagcat caacagaagg cattaatgta
    41401 gtcaccaata gtattatagt aactattatt gcttgaagta taactgcttt agaaggtatc
    41461 ttgtgttcat ttacctctac taaactatct ggaaatattc cttttttaac actaccaaat
    41521 aacattttta ttggtgatgc tatgtaaaga actattgctc ctaatactga aaaagctata
    41581 ccaaaagcta ttaattgaac caaccaagaa ccaattccta aagacgcaca aacagcagaa
    41641 agtgcatcta atacaccttt agaagcagta atttggtctg gtggtattat cattgttatt
    41701 gcaattgaac ctaatacata taatgaagct actattccag ctgatattaa tattgcctta
    41761 gggaagttct tttcaggctt atctatttct gttatgaagt tagcagcagt ctctgctcct
    41821 gctaaaccaa acattatagc tgatatagca acaaatgcat ccatattaag ttttggagtc
    41881 attgaagcta ttgtgtatgt agaagctata tcatgttttt tcaacacaaa tactgctaca
    41941 aatgaaaata ttataagtat agcacttggt attgttgaac ctaatgcacc tgtattagta
    42001 aatatttttg taaaacttat tcctttagtt gctataagag ataatgccca gaatattatt
    42061 aaagataata taagtacaaa catcttatta tcagcaaggg ctggatttcc tattgtataa
    42121 gaaacattta ctgctaagaa agttaaaaat gaagaatacc aaaatatttt agctgtccag
    42181 tttaaccaag aaactaaaaa tccatacttt tctccaaagg cttccttaac ccaatcgtaa
    42241 agacctccat cacctttttg atatgtagaa gctaattcag cacaaattaa agctcctggt
    42301 acaaagtata taaatgagaa taataaccac ataggtattg cacctaatcc taaaccaaag
    42361 cttgatgctg tagatttagc tatccatctt ataccatata aagctgatac attcataaat
    42421 accaaactcc ataggcctat ttttttcttt tccatcctaa tttaatttcc cctctctatt
    42481 aattatttta aatttaattt caaaattaat aaaatagatt cattattatt aaactgatat
    42541 ttttcaaaat atttgcatat tcaaaaacag ttttaataat aaaccttaaa tactttgaaa
//
LOCUS       DAEOTL010000029        40052 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEOTL010000029 DAEOTL010000000
VERSION     DAEOTL010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40052
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.029"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            84..898
                     /locus_tag="KRH82_001843"
                     /pseudo
     CDS             84..898
                     /locus_tag="KRH82_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            950..1111
                     /locus_tag="KRH82_001844"
     CDS             950..1111
                     /locus_tag="KRH82_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655123.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(1439..1903)
                     /locus_tag="KRH82_001845"
     CDS             complement(1439..1903)
                     /locus_tag="KRH82_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655124.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVFEDMKNKILRERKYKKRR"
     gene            complement(2039..2356)
                     /locus_tag="KRH82_001846"
     CDS             complement(2039..2356)
                     /locus_tag="KRH82_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655125.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(2639..2935)
                     /locus_tag="KRH82_001847"
     CDS             complement(2639..2935)
                     /locus_tag="KRH82_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655126.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(2954..3367)
                     /locus_tag="KRH82_001848"
     CDS             complement(2954..3367)
                     /locus_tag="KRH82_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655127.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(3351..3584)
                     /locus_tag="KRH82_001849"
     CDS             complement(3351..3584)
                     /locus_tag="KRH82_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655128.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            3803..4177
                     /locus_tag="KRH82_001850"
     CDS             3803..4177
                     /locus_tag="KRH82_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8655129.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            4789..5481
                     /locus_tag="KRH82_001851"
     CDS             4789..5481
                     /locus_tag="KRH82_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655130.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            5677..7737
                     /locus_tag="KRH82_001852"
     CDS             5677..7737
                     /locus_tag="KRH82_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8655131.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(7943..8266)
                     /locus_tag="KRH82_001853"
     CDS             complement(7943..8266)
                     /locus_tag="KRH82_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBG8655132.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(8259..8960)
                     /locus_tag="KRH82_001854"
     CDS             complement(8259..8960)
                     /locus_tag="KRH82_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBG8655133.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(9238..10623)
                     /locus_tag="KRH82_001855"
     CDS             complement(9238..10623)
                     /locus_tag="KRH82_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8655134.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(10731..10874)
                     /locus_tag="KRH82_001856"
     CDS             complement(10731..10874)
                     /locus_tag="KRH82_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655135.1"
                     /translation="MYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKEGIKIIGRF
                     EIN"
     gene            complement(11069..11491)
                     /locus_tag="KRH82_001857"
     CDS             complement(11069..11491)
                     /locus_tag="KRH82_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBG8655136.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            11969..14872
                     /locus_tag="KRH82_001858"
     CDS             11969..14872
                     /locus_tag="KRH82_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655137.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            14905..15351
                     /locus_tag="KRH82_001859"
     CDS             14905..15351
                     /locus_tag="KRH82_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655138.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            15474..15776
                     /locus_tag="KRH82_001860"
     CDS             15474..15776
                     /locus_tag="KRH82_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8655139.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            15957..17363
                     /locus_tag="KRH82_001861"
     CDS             15957..17363
                     /locus_tag="KRH82_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBG8655140.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            17707..18765
                     /locus_tag="KRH82_001862"
     CDS             17707..18765
                     /locus_tag="KRH82_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBG8655141.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMEKGDIIFKPMISDKIGLNEVGDF
                     LSKMSKREINFNKILVEM"
     gene            18864..19550
                     /gene="araD"
                     /locus_tag="KRH82_001863"
     CDS             18864..19550
                     /gene="araD"
                     /locus_tag="KRH82_001863"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBG8655142.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            19568..20215
                     /locus_tag="KRH82_001864"
     CDS             19568..20215
                     /locus_tag="KRH82_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBG8655143.1"
                     /translation="MLDSLKGKVVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GVGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(20388..21755)
                     /locus_tag="KRH82_001865"
     CDS             complement(20388..21755)
                     /locus_tag="KRH82_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBG8655144.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTISLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(21945..22033)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            22461..24581
                     /locus_tag="KRH82_001866"
     CDS             22461..24581
                     /locus_tag="KRH82_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBG8655145.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLKSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            24685..25938
                     /locus_tag="KRH82_001867"
     CDS             24685..25938
                     /locus_tag="KRH82_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBG8655146.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(26092..27153)
                     /gene="ytvI"
                     /locus_tag="KRH82_001868"
     CDS             complement(26092..27153)
                     /gene="ytvI"
                     /locus_tag="KRH82_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBG8655147.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            27427..28167
                     /locus_tag="KRH82_001869"
     CDS             27427..28167
                     /locus_tag="KRH82_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBG8655148.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            28179..29957
                     /locus_tag="KRH82_001870"
     CDS             28179..29957
                     /locus_tag="KRH82_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8655149.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            30124..31041
                     /gene="pfkB"
                     /locus_tag="KRH82_001871"
     CDS             30124..31041
                     /gene="pfkB"
                     /locus_tag="KRH82_001871"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBG8655150.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKGGALLITEEEEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            31078..32997
                     /locus_tag="KRH82_001872"
     CDS             31078..32997
                     /locus_tag="KRH82_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655151.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIFLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            33491..34498
                     /locus_tag="KRH82_001873"
     CDS             33491..34498
                     /locus_tag="KRH82_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8655152.1"
                     /translation="MIFTIIFYKKGRLCLLNLQSKWVNFLKPTYVSDEIKRKKLQVII
                     FFSITYGLSYSLGLLAICFNHLIDSEILAQFMMILPLSSVSIAKFYTEGRNNDKYNFY
                     SSVILFFIIYFFIFIIESLKLISINQFQLMYLMLILISSLCVIVYSYKITSLYIFKNF
                     KIGILLFFYFLFSQIIFGLIISDNQFDYKNFLNYILLPIISLVYIYPFLCEEYGWRSF
                     LQSILFDRFGKKIGIVMVGTCWSLWHLPLQFTLYSPQTPIIGAIAHLIYGIGLSIFLG
                     YVYMKTKNIWFCSIMHVLINSLGLIFNDSEIIINYHSIIQRLIFILLFYTPFLFTKEY
                     K"
     gene            34878..36404
                     /locus_tag="KRH82_001874"
     CDS             34878..36404
                     /locus_tag="KRH82_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBG8655153.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VKQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            36432..36989
                     /locus_tag="KRH82_001875"
     CDS             36432..36989
                     /locus_tag="KRH82_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655154.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            37511..38554
                     /locus_tag="KRH82_001876"
     CDS             37511..38554
                     /locus_tag="KRH82_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655155.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VEGEKIDLNKFEGLDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            38665..39807
                     /locus_tag="KRH82_001877"
     CDS             38665..39807
                     /locus_tag="KRH82_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBG8655156.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYIFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT        16046 a         4210 c         6528 g        13268 t
ORIGIN      
        1 aacccctatg acgtatacta tcgtatatca attatagtat atgtcattcc ttaaaaaaat
       61 caattattaa ggagtgtaat attatgaaaa atgaattaat gatgtttgaa ggaaaagaga
      121 ttgaagtatt tgaatttgaa ggaagaattt tattcaactc aaaagatgta gtaaactgtt
      181 tagacataaa aaatgttaat gagaatataa gacttatgaa tgaaaagcaa gttgtaaagt
      241 taagaaattc ggatatcagt aatactgaca tccgaaaact taataatgct ggagaaaatt
      301 ttcttactga aagtggagtg tataaattaa tctttaaatc aagaaaagaa gaagctgaga
      361 gattccaagg ctggataagt gatgaagttt taccaagcat aagacaaact ggtgcataca
      421 taaataataa tgcaataccg aaaagttgag agaaaaagca agtgagattg aaaaattaca
      481 gttggtttat aacagtacat ctatgttaaa agaattgcta gatgatgcag gctttgacaa
      541 taaatcaaaa ctattaacag ctaaaacatt atataagaaa gcaggaattg atttaccaat
      601 agagataaac gaagaagaac attattttga tacaaaacaa atagcatcta aactgaaaat
      661 atattctaag agtaataaac cagctcagat ggcagtttgt gagattatta aaaagattga
      721 tttagaagat ggtgaagtta aaggtgtttg ggaaattaat ggttcttgga ctggtactgt
      781 aaataaatat acaaagagtg taatagataa ggtgagaact tggatagagg aaaataatag
      841 acctaccaag attgcaggtg agaagaagaa ttattatgta ttttacaaaa ttgagtaaat
      901 ttatcagttg tattaaataa tttagtttag ttttgggggg attaatacaa tgtgtgagaa
      961 tttacttgat aatatgtata ttgaaaagag aaaagaagaa tatagaatta aacttttgaa
     1021 aataagagaa acagatatag atatatataa taagttagaa agtatagtat ataaactttc
     1081 tgagaaaaaa ttagagaaaa ataataaata gacatataaa gcacttggat attctactgt
     1141 ttcaagtgct tgtttggtat aaaatggtat aatggagata gagaattata ttaaccaaaa
     1201 aatggagaaa atagagaaga tgatttagtt gacgctttat cagtaggagt acctgtaggt
     1261 aagacagaat ctctagtacg attagttgga gatggaataa gtgatactca aaaaagttta
     1321 ataaataaaa gagaatttag aaatataact caaattggtg gaaatggaaa tgagaaagca
     1381 tttagtgaag tagaaaactt agttaaatag attagaaggt agcaactaga gttggttgtt
     1441 accttctttt tttatacttt ctctctctaa gtattttatt tttcatatct tcgaatacat
     1501 ctaatgcagt agtataaaat tgtatattat ttctataagg tatagctatt ggaagaatgc
     1561 ccttgttaac taaaaaaata agaagtacaa taaataaaag tgtcataatc attctaataa
     1621 aataattagt gatatctgat aaatcaaatg ttaagttaat tgttgtagaa aatacaacag
     1681 ccataataga tatatacaaa gcaaaaatgg ggttactatt tttttgtaac tgtcctttaa
     1741 gcctagattg ctctatttct atatcttgaa tactttttat ggaatccatt tcactataat
     1801 acttataaac ttttaaataa tattttttat acttgtttaa agcttcttca ttatctttaa
     1861 ggtctttgtc acttaactct gatttaactt ccccaaaatc cataaaatcc ctcctacaat
     1921 gttatataat atactttaat ttatagcata tttaagaact tatatcagca atttgtcgaa
     1981 cgattttagc taaaaataga gtataatgat aggcttatta tttataagat attatttttt
     2041 atatagttat atatttcttt ctaattagat aatataatgc tgttgttata atggctacta
     2101 atattattgc tattattgta atatctaatc ttcttgtaaa taagcctatt gctatatact
     2161 caagacctgt tacatagcga taaagtactt ctagtttaac agtttttttc ttatctatat
     2221 ttccatatat tgattctaat ttattaaaat attttttact acaaaaagca gttttaggtt
     2281 taattaaata tattattgta gttcctatta taactattat tccaataagt ataagattga
     2341 tatttccaaa atccatagca gatacctcct attaaatttg cttttcttaa tcaaagtata
     2401 tcagtaacac aagtacaaag agtatctaaa atattacaaa tattaacagg atagataaaa
     2461 ctatagtaaa aattgtaata ataaagcgaa cgaaaattat catactaaaa cataagacat
     2521 gttataattg tattagatag aagattaaca tacaccaaag cactccttat aataaagagt
     2581 gcttattttt ttgaaattca tcaatatata aactatcaag aaccttattc aacacacctt
     2641 aaaatcgatt taaatagctc tttttgataa cataatttat atgatataat aaaaaaatag
     2701 aagtgtacca ccaatacact tctatagcta taactaagca ttctcttgct gggggagtgc
     2761 ttttttcatt tctccaaaca acattattta cttcatcagt aattatcaaa tcaatctcat
     2821 tatctttcaa aatctctgtt gcagtacaaa ttagattatc taagtcaaaa cttcgagtta
     2881 tctctagttg tttgttattt acttctcttt ttagtatata agttttaaaa tacatttata
     2941 tcaccccttg tatttactct tttttctcta aaaatatatt gataagtaaa tatgcaacaa
     3001 ataaaaaaat ctcaatgaca catagtgtta tagctataac tagaagtgat tgatttttcc
     3061 atgcactata agctatgatg aaaagaaatg taaaagtaaa taatgtataa ttcataattt
     3121 taactaagat atgacttgtt ttcattgtta agtacaagtc tctttcatct gtactatcgt
     3181 gtaattcttc aacaatgcct tttcttgaaa aagcattaca aaaattaaag attgctatta
     3241 caattaaaag aaatgatgaa attaggaatc ttttatcttt taaaatgcaa taaataacta
     3301 aactagcaca acataacaca caaactataa tacccactat aaaacttcgt ttactcttta
     3361 ctttcatgtt ttttatcctc catttcttta ttttctttta aacaacatag ttcttcaatc
     3421 gttgtaccaa acacttgtgc catacgatag gcaagcataa gagaagggct atattgctct
     3481 ttttcaatag aaataattgt tctgtttgat acatggacta aatcagcgag ttgttgctgt
     3541 gttagaccca tatttgttcg aaattctcgt acttttgttt tcattccata acctctttct
     3601 atatgaagct aacttcatgt gaagttaact tcataatatc ctaaaatgag taaaatgtca
     3661 atctcattag ataagtatta taaaacctaa aagaataata tggtaaaaat tggatggaat
     3721 tatttacctt aattctcttg tttgtaaaac tttattgata tagaatttaa catatacata
     3781 aatcggcaaa ggggcgcgaa ttatgaaaat tagtaaatta ccagaagcgg aattaaaagt
     3841 tatgagatat atttgtgaag ctaacaaggt attaacttct agggaattag ttgctgcaat
     3901 ggaagaaaaa tatgagtgga atgaatcaac tacatttaca gttttgaaaa gattagagcg
     3961 aagggagttt ttaagtacag agaaaatagg caaacttaca cattataata tactagtaaa
     4021 agagaaaaaa tatctaaggt ttgaaacaaa ggaatttttg aagaacatac ataaaaattc
     4081 aatttcaagt ttaatgtcag cgttacatgg tgaagacgac gaagtggatg aagataaatt
     4141 aagtgaactc gaagaatgtt ttaagaattt gaaataagaa aatgacaaat tgatacataa
     4201 taaataaaat gaaggtatga aattataact ttttctacct tcattttgtt tattattctg
     4261 aacatgttaa gaaaatgaaa taagtttgta ttttagttat ataaatttta atagaatatg
     4321 tacagtatat agtagataga atgtataaaa atagaattta aataagtagc tattattgca
     4381 gtgaaatgaa tgtttctaag tatatttggg tggaagaatg gtggaagaaa attagtgaaa
     4441 tgtaattctt ccaccattct tccacctaga aaatagaaac tgtttaataa gaattaatat
     4501 acattaattc agctgaatgc aatcaaaata cttaaatgaa agtaatctga aaacaacata
     4561 attcaaatca atttattcaa ataaacctca atttatctta aatcttaaga aatatttaag
     4621 aattaggata atattttctt aagatttata ttttattata tagttataag ggaaagttac
     4681 aaaaatgtaa gccaaagtaa tataacaatt tagtcattgt tgagaaaggg agtgaaagat
     4741 attgtataat atagataagt attattatac aatagaggaa gtgaaaatat gtacaatata
     4801 ttagtagtag acgatgataa agaaattgtt gattcgatag aaatatatct taaatcagaa
     4861 ggatttaaaa tatataaagc atatgatgga atgaaagctt tggaaataat aacagagaat
     4921 gacattcatc taatactaat ggatataatg atgcctaaat tagatggaat caaagcaact
     4981 gtaaaaatac gagaagaaag aaatattcca ataattttaa tttcagcaaa aagtgaagat
     5041 acagataaaa taataggatt aaatattgga gctgatgatt atataacaaa gccatttaat
     5101 ctattagagc ttatagctag ggttaaatca aacttaagac gatatgtaac tttaggtaat
     5161 tatgaagata catgtaaaga aattttaaaa agtggagctt tggagttaaa tacactaaca
     5221 aaagaagtta aaattgatgg tgaaaacata aaaatgactc caattgagta taaaataatt
     5281 gaacttcttt tagaaaataa aggacgagtt ttctcaatag atgagatata cgaaaaagta
     5341 tggaatgagg aaagttttaa ttcagaaaat acagtagcag tacatatcag acgaataaga
     5401 gaaaagattg aaataaatcc aaaagaacca agatttttaa aggtggtgtg gggagttggt
     5461 tataagattg aaaaatttta gtggaaaaat tataaaagaa aagagtttaa tatttaattg
     5521 cattttgatt ttagtcattt ttacatttac acaaatgtta ggaattttaa tatgttttaa
     5581 ttttttctct gagagtttaa tttactctat ggggattatg cttttcttaa actttatttt
     5641 atataaaata ctgacaatgt agatgaggtg ggcaacttgg agaaatatag agtattaaag
     5701 ttagtttcat taatcataat atctatctca tttccattaa ctatattgtt ggtgacaata
     5761 ggacttgctg agcctaaata caatatacaa aaaacttcta caaagagtgg gatttttgat
     5821 atatctgatg atttttatga tagtaatata tttgacgaag gaacaatggc aagtctatta
     5881 cccaagttta agctatctgt aggtggtaaa ttaactagta aagaaaaagg taaattccaa
     5941 caagaaggta aaagtataga tttaagtagt agtgattctg agtatgataa aatcatgatt
     6001 aatgaacaag cttctgaaga atatttaagt tatctaaaaa atataaaagt gtatgttatt
     6061 aatacataca caggagtatt ttatacaaat acgtcatatg ctagtttata tgattttaaa
     6121 caaaaaacta agagctattg taatgtagag ataataaata agataggaaa gagctcatat
     6181 attaaaacaa taaatggaga aaaatttgaa ctgaataatc tgagtctgga actaaatgaa
     6241 gtagatgaag gttttgaggc atatgtatct tttccagaag agccaactat agaagatgga
     6301 atagtatata ctaattttca aatatttaaa caagctacag aaaaagtaag attatttttt
     6361 gtagctagtt taagtttagc aattatatgt ttattatcta taattttata tatcaaaata
     6421 aaaggtgaag ttttaaaaag aaataatgta tttttactaa tatacagtaa gatacctatg
     6481 gaatttaatg taatattagt atctatttca attgcaattt taactatata tgctcttgct
     6541 gtatcttatc atattgatgt aattgcatta gtttctttat ctttactgat agtatcaaat
     6601 aatatatttt ttataaatgt gcaattgagt tatttagaaa ataaaatgtg tatatttaag
     6661 acaagtatta tagtaagagt gattttatgg ttaataaaaa ctgtaaggga ggtcagtaac
     6721 gctataaaga aagtatcttt agcaaggaaa gttattgtta tagtgataat atctttagct
     6781 ttaatcatgg taattagcac tcgaagtata ggtatgggat tactgttttc tatatgtatt
     6841 tttttaggat ttacaatata tataactaaa agactttcat atcttagtta cgtaatagaa
     6901 ggtacagaaa gaataaaaaa gggagaatta gattataaga taaaaattac tgggaatgat
     6961 aattttacgt ctttagctga aaatataaat aatattggag aaggtcttga tagagctata
     7021 gaagagcaag taaaaagtga aagaatgaag tctgacctta taacaaatgt atctcatgat
     7081 ttgaaaactc cacttacttc tataataaat tatgtagatt taattaaaaa agaagaatca
     7141 atacaaccag agtatataaa tgattatata aatgtacttg agtcaaagtc aaaaagacta
     7201 aaattattga tagaagattt atttgaagcg agtagagtaa gtagtggcaa tatagaatta
     7261 caaattagca agattgattt agtgcaacta ttaagacaaa gtataggtga acttgaagaa
     7321 aaattatcta aaaataattt atatttaaaa ttaaatgttc caaatgataa ggtgtatata
     7381 tgggcagatg gaagaagaat gtatagagta tttgaaaatc ttttatctaa tatagcaaaa
     7441 tattccttag aagaaactag agtctatatt gatgtatatg actatggtga aaatgtaaag
     7501 gtaactatga aaaatatatc ttcttatgaa ttaaattttg acccaagtga gattatggaa
     7561 agatttaaaa gagctgatga atcaaggaat actgaaggaa gtggattagg gcttgctatt
     7621 gcaagagatt tagtagcttt acaaggtgga aaattttata tagaaataga tggagattta
     7681 tttaaagcaa atttagagtt tcaaaaatat gaagaagaaa taacaaatat ggaatgagat
     7741 agtatttaag tatatatatt ttttttactg tcgaaagctt ttattataat atattagaat
     7801 atttacagta gagaatgaag agtaaaaaca gagtaacttt aagtcactct gttttttatt
     7861 taaaatcaat aatataacaa cttaaattaa aattgtacac atagttttaa aataacttat
     7921 acaataaaac attatccaaa tatcacaaga taattccaaa taaatatata gatatcactc
     7981 ctgtaataat agaaatacca atagatttaa acttatatgc aacaagaagt acaatcataa
     8041 aagatataat tttagggtta gctatagata aatatagact atctccatta aaaaatacat
     8101 ctttagcagt taaggaagta agtattgcta caggtataaa tttcatgatt tttttcaaaa
     8161 aatcaggcat ctcttttttt gaaaaaatta acataggaag cactcttggt agatatgtaa
     8221 caatgtacat tccaattata ataaaaaata tataattatt attcataaga ttcctccttt
     8281 ttacagtaag attcttctat aaagaaacca attaaagatg ctaaaattga tgcaactatt
     8341 attactaaat tgcttttgaa taatgcatat aaaataacag aaataatgat tgatgatata
     8401 aatactacaa tataaatctt attttttatt tgagaaacta ttaaagctat aaacatagaa
     8461 gtcaatatga agccagaaat agaactgtct atagatatac tttctcctaa aaatgctcca
     8521 ataaaattag ctaaaactga tgaaattaag cagaagaaat taagataaat agcatttcta
     8581 tcagaccaat ttccagcagt aaatttttca taattaactg caaaagtttc atctgttata
     8641 gtatgacaaa atggcaatat aaattttgga cttttatttt ttatgtacat gttcaaatta
     8701 gaactcatta gaaaatgtct taagttaact ataaatgtag tcaaaacaat agatgttaca
     8761 cttgcaccag tagaaatcat tgaagctgca atgaattgag aacttcctcc aaatactaaa
     8821 gttaccatta gtgctatttg aaaaggtgaa agaccagatt tttgtaatag tattcctcct
     8881 actataccta taggtatata acctaagaat ataggaattg aagcaataaa gctttctttt
     8941 aattgttgag ttctttccac aataaatcac tccttttgta ttaaatgtat taaagtattc
     9001 gtaaaacaga aaaatagatt aattgtataa ttgcaattat aattaaaaat aaatttggat
     9061 taatatataa aatactatac aacaaataga taatcttaaa cggttattaa attttatcta
     9121 tttgttatta tgatgtaata atacatatta atctctataa gttaattact atctggtgta
     9181 attttatttt aacaacaaaa aaaaatacac acaattaaaa tattgtgtgc aatacaatta
     9241 ttttttctct tctaatagtc tttttaatac gctcaaacca gctttaagtt cttctgtact
     9301 ttctgtagca catacagcta ttcttattgc agaaattggt ttttcttttc caacagcaaa
     9361 acgttcagaa gcatagacct gtacaccttc tttaagtgct tgtatctcaa atttttctgc
     9421 cattattcca tcaggtagaa tcaaccatct aaatatacat tcttcatttc ccaaaagatt
     9481 atatccagat aaatattgat taataatctt gtttcttctt cttgcagatt tacggcgtgc
     9541 attaattaat ttatcggctt cacctgatgt aatcatgcga taagcaattt ctgttaaaaa
     9601 ataagattga gatagattaa tgttgtataa tgcgcttgat aatgcctctc gatactgttt
     9661 aggtgtagag atatatgcta gccgtaaact aggtgcaata atttttgata aactcgtaat
     9721 ataaattgtt tgattgggca gataggaagc cactggattt aaatgtgttt cattaagtaa
     9781 actatgaata gcatcctcaa taacaattaa attgtattta gatgcaatat ttgcaatcat
     9841 ttttcgtcca ttttgtgaca ttatatgtgt agttggattt tgataatctg gtattatgta
     9901 tagaccttta atattttcat ttttacaagc atataatagt ccttcttcac taatctcatt
     9961 atcttcttgt ttaattggaa ttagttgaat cccaagcatt ttagctgctg tctttattcc
    10021 aggataagtt aatgggtcta cacctattct atctccatgt tgaaacaaac cagctaaaat
    10081 agcaacaatt gcattttgtc caccacttgc aggaagtaag ctatctgatg tagtttcaag
    10141 cccagcttta taaattaatt tggcaatagc ttctttttgc catttagcac catctctttg
    10201 tccatattgg aatatagttt taaaatctat ttccttaatt atgtgtttaa acaaagtatt
    10261 catttcttct agcgtgaaat ctggattcat tgtgcccatt tcaataaatg taattttatt
    10321 attactggac atcaagaata gatttgaacg tgtatcataa gatacaaaag ttccacttcc
    10381 tgtaactcca cttattagac cttttttttc acaaatttta aaagctctag agatagtact
    10441 cacattaaca tctaagaaat ctgccaattc acgttggggt ggtaatttag tacctggtaa
    10501 taaaaatcca ttgttgatat cttgttctag ttgttctgca agagccttat ataatatttg
    10561 accttttgaa ggtctctttg gtttccagtt cataggataa ttttcaaaag aattaattgg
    10621 cataagtttt cacctcacat tattaatttg attttttctt tatctaaaac aataaattct
    10681 aaagatacaa ataaaaactg ataggaaata attctatcag tttttgtctt ttaattgatt
    10741 tcaaatcttc ctataatttt tataccttct ttatcataaa gagggattgt ttttttaaat
    10801 atattaaaat ttctttttct tgtatataaa acagcttctt ctggtgtctt tggttgatta
    10861 tcacaatcgt acaaatttct tttttttaac taaaagcaat aatacataaa attattattg
    10921 ctaatgatac tcttaatgtg gtatatagtc atagtgtcac atgtctatca atagtttttt
    10981 cagtaattat tgtaacgaat agtaggactc ataaaatact tagaaatatg tttttagata
    11041 aattttaaat atataatcta acttatatct ataaattaac actattattc tccaattcca
    11101 tttctagttt ttttataaat ttattaaatt cttctggttg cctttttcca aacaatactc
    11161 ttacaagagc tgaattgatt tttccaaata tattcctctt gctctcactt tcaataaaaa
    11221 taagttttgt attttctaag tcaatatgta ctaattcata tctagtaata gtactttctc
    11281 ttttattgct tgtttttatc tcatatactc tatttttttc gaaattagtt atttcaacct
    11341 taaatctttt attatttttt tgctgtacaa atgttcctac tgcttttttc tcattaaaat
    11401 taggaaaatt tagtcttgca gattttgtaa atatattaaa tatgtctttt gcagaatatt
    11461 ttaataaaac ttcagtttta aatgtattca tatcgttttc ccttctgtat ataaatttaa
    11521 tatttataag ttaattttta agttaaaata gtataatatg ccatattaaa tcatgttaaa
    11581 actatttata tagctaaaat cttacctata taagtatgta tactatcata taaaaataaa
    11641 atcttaaaat agaaagggtt aaaaacacag tttattataa tttttattgt tgagtagata
    11701 cgtactatta tatatgattg agcaagtttt tcaatcataa atttataaag tattttgcat
    11761 taaaatttaa acaaagaatt aaattattta agattatgaa taactaatac atttagtaaa
    11821 ttactaaata tacaaaatgt aaatacttat caaaatgtat aaatacttat gacatctagt
    11881 tacttacagg gtttaagtag aaaaaaatat caaagtaagt atggcatgat agttgcttat
    11941 atatttatca agaaaggagt tattaagcat ggagttgaga gataaacttg taaacatcat
    12001 aaatacagaa aataaaaaag atccattaac agatgttcaa atagcaaagt ttttaagtac
    12061 aactagagag aacataacta atttgagaaa agaacttaat ataagtaatt caaggcaaag
    12121 aagatatcct tatttaaaat cagcaatttc ggcaatatta caaaagaata agaatatttc
    12181 tatatcagaa attacaaggg aattgatgac agaaggcttt aatatatcta gaagagttgt
    12241 ggaggaactt ttacctaaag aaagtttaga aatggatgta gtagaggaat ctgaagaaga
    12301 atcgaatgac ccatttgaaa ctctgatagg taataaaggg agtcttagaa atgctgtaga
    12361 gcaggctaaa tctgctatat tgtatccacc aaaagggtta ccaacgttga ttattgggga
    12421 aagtggagtt ggtaagagtt tattttctag acatatgtat gagtttgcaa agcaaaaaaa
    12481 gatagtaaaa gaaagctcca attttgttgt atttaactgt gctgattata gtgacaatcc
    12541 acaattatta ttatctttgt tatttggata taaaaaaggt gcatttacag gtgctgaata
    12601 tgatacacca ggtcttgtag aagaagctga tgaaggagtt ttatttttgg atgaaataca
    12661 tagattgcct ccaaaaggcc aagaaatact attttctatt ttagataggg gaaagtttag
    12721 gagattaggt gaaactaatg ctgaaagaaa agtaagtatt atgttgattg gggcaactac
    12781 tgaaaatgta gagactaatt tattattaac attcagaaga aggataccaa tgctaataac
    12841 tttgccacca ttacatgata gattactaaa agagaaaata gaccttatat acaatatctt
    12901 tcaacaagag tgtaatagaa taaatgcaaa aatatttgta gataaaaatg tgattgaaat
    12961 acttgcacta aaaaagttta gtggaaatat aggacaatta caaaatatga ttcaggttct
    13021 ttgtgcaaga gcttttatga agtttataaa ttccaaagat gaagatagtg aatcgatagt
    13081 agtagtagat ataaatgaag ttttaaagct taaagattct tttaaagatg ctgcctttca
    13141 agagattgaa tatacagaga taagaaaata tttgaaaaat gctatattta taccatttaa
    13201 tttagaagaa tcatcagtaa aaggaagtct tttaagtgat gaatatatat taccagagga
    13261 catatacaaa acaattgaaa agaaatatta tgacctaaaa tccctagaca ttgaagatat
    13321 agatatagag aatattttat ggacttttat tttaaataga tttgctgact taaagtttaa
    13381 tctcgatagt aatgaagaaa ttttttcaat gagtgattta aatagttttg taagtgatag
    13441 tttagttaaa ctggtaaaag aacttatgaa tgatatagtt gaaaaaaata tgaatttaga
    13501 agtaaataaa aatatgttca aatatctagc aatacactta gaagaagcta taaaaagaat
    13561 taagctaaat caaaagataa taaatgtaaa tttagaaaaa ataaagattg acttttcaaa
    13621 agaatatgaa attagtaaaa gttttgcaat aaaaattgag gaatcaattg gtattaagat
    13681 tccagatgat gaaattggat ttataacact ctacataaag tctgctctaa aaaatgaagt
    13741 gaaaaaagat aaagtagggt taataataat ttctcatgga cgtatagcta cagagactgt
    13801 aaatgtagtt aaagaacttt taggtgtaaa gtttcctgtg gctatagata tgcctttaga
    13861 tgaaaaacca ataaatatat acaataaggc agtagaactg tcaaaaataa tagaccaagg
    13921 gaaaggcata ttgtttttgg tggatattgg ttcacttaca aacataggtc aaatagtaaa
    13981 taagagaacc aatataagca ctaaaactat tgatagagta gacctcctaa tggcactaga
    14041 agcaactaga aaagtttcta tgggagagga agaacttgat gaaatatttt tttctttgct
    14101 aaaagatagg atgggatata actatgaatt agaaaaacac atagataaat caaatgcaat
    14161 tataacatta tgtcttactg gagaaggaac tgctaagtat ataagtaaaa cgttggaaga
    14221 aaagtatgat aacactaaat gttatcaaat gagtgcattg gatgaaaatt tattttgtaa
    14281 aattgaaaat ctaaaagaga caaacaatat attagctatt gttgggacaa taaaccctaa
    14341 gataccaggt ataaatttta taccctataa taaagaactt ttcaaaaatt tggatatcta
    14401 tctatcaaaa tcaaaacaac aagatgacag accaattaaa tcgtatgaaa gaatgcttga
    14461 tgaggattta gtgatttttg aaccagatat atattttaaa aaggatttat tagaatatgt
    14521 atgttcaatt cttataaata aagaatatgt agaaaaagat tacttagatt ctgttttaca
    14581 tagagaagaa atgcttccaa catattctaa aggagctata ggtgtgcctc atggagattc
    14641 ttctactgta aatagtacaa ggtttgtttt tgttaaacta aagaatccta ttgattgggg
    14701 tgtaggtaat gtaaatttca tatttatgcc agtttttcag gctaatgata aagagattgt
    14761 taaaaatgtt cttgagatac taaaagatgc agaatttatg aacaatgcca ataagtgttt
    14821 tgataaagat gcttttagaa ggattatatt tgataaattt aaacatctgt agccatagca
    14881 aaaaaattga gaggagttag agtaatgaat gtagatttaa tatcattggg tttagaatct
    14941 aatgattatg aaagtgttat tgaagaatta ggaagtataa tgtgtaaaaa agaatatgta
    15001 aaagaaacat acataaatgc tgtcttggaa agagaaagga cattaccaac aggtctagat
    15061 attggagaaa tgtgtgttgc tattccacat acagattcaa agcatgtaaa tgagtctaat
    15121 gtagctgtag ggatattgaa aaatcctgta aagtttaatt caatgataga cccaaaagat
    15181 agacttgatg tagaacttgt atttttatta gcagtaaaga acccagattc acaagtaaaa
    15241 ctgttaaagg atttaatgtc agtttttcaa aatataaagt tattaaaaaa tataaaaaac
    15301 gcatcaacaa aagaagaagt agctaaatta ttggacttta tagaaattta atgtaggaga
    15361 attttataaa taaaaaatta aaatttaaac aatcaaagta agtattattt ttttaatagg
    15421 tttaatctta tataaaataa aaatttagag tgaaaaatta ggaggaaata attatgaaac
    15481 aatttaatgt attatcagtt tgtggttcag ggacagttac atcatctatg gtagcaggta
    15541 aattaaaaga agtactaggt aataagggga tttctattac tacaacagaa gctagaccaa
    15601 cagaagcact aaatttagca caatcaggaa gatttgactt tataacattt acgagtccac
    15661 ttcaaacagg cgattatgga ataccaacta taaatgcatt tgcttgccta actggtatag
    15721 gggaagaggc attctttgaa gaagttttga ctgttattga agggatagat aagtaagttt
    15781 tggagacgtg aatttatagt atttaaatca atgacttaga tactataata agctaatatt
    15841 aactaaatat ttgtggaaaa aacattttat atgttgtcat aaattaaaaa attataaaaa
    15901 tagtcactta agtattaaat taagcttata aatatttata agtaggaggg aaaaagatgt
    15961 tagaatttat gaaatctata atcgatacat ttggttctgc aattatagtt ccaattataa
    16021 tattcataat cgcaaagata tttaaagtaa ctactaagaa atcgtttctt tctgctgtgt
    16081 atgcaggagt tgctttacaa ggttttacac tgattttaaa ttcatttaca ccaataataa
    16141 caccagttat caataggatg gttgagagta caggagtaaa cctaccagtt tttgatgttg
    16201 gttggcaagc aacatcattg gttgcatttt caacaagtgc aggtatgata tatttaggtc
    16261 ttggtatatt attacaaaca attttatttt tgataaaatg gacagacgtg tttcaaccat
    16321 cagatttatg gaataactat tcttatatgg tatggggagc aatggttata ggagtaacag
    16381 gaaattttcc tttaggtata gcatgtatgg ttttattaaa cctatatagt ttattaatat
    16441 cagagttagt tgcaaagaga tggtctagtt actatagata tcctaattgt acaataatag
    16501 ctatgcataa tgttgaagct tctgtgtttg cagtatttgc agaccctata tacaataaat
    16561 tgggattaaa taaaataaaa ttaaatccaa aagaattaga gaagaaatta gggtttttag
    16621 gtgaaccaat tactttaggt ctttttttag gtatgtttat aggtatatta ggtaatatga
    16681 cgagaataaa tactatggaa gcttggggag aaataatgaa agtaggtata tctacaagtg
    16741 cagtgatggc aattttccct aaagtagcaa gtatgtttgc tcaagcattt gcacctataa
    16801 cagaagcagc tagaaagatt atgcaaaaag ctggaaaccg tgagtggtac atagcagtaa
    16861 atgatgctgt tggatatggt gaacctgcaa ctttaatatc aggtcttata ttaattccaa
    16921 taatgcttgt aatagctatg gtacttcctg gtaataaggt attaccagtt gtggatttat
    16981 tggcaattcc atatatggtt caaggtttag ttgccataca taatggtaat ataccaaaag
    17041 tattagtttc aggtataatt tggtttggat taggattata tgtttgtaca tctacagcac
    17101 cattatttac agatatggct acaaatatag gtgtagctat acctgcagga gcaatgttaa
    17161 taacaagctt taatatacta ggaaaacctt tgatgggatt agttttcttt gcatttctaa
    17221 gtgcaaatcc aatttatata ggtctttcag ttgtaattta ctttgttcta tgggcattgt
    17281 ttagaaagaa caaaacaagt attcttgatt atttagaaaa acaagcactc aaaaatgtag
    17341 aagaagagcc tgtagcagtt taagtttata aaaatgaaat aaaaataatt aaaggagttt
    17401 ataattgatt ttatataagt atcagataat acctgagaaa tatttaaatg aaatatagac
    17461 ttctttttat ttgataatat ttgtaattat aatgcattgt atttttatag ttgagttttc
    17521 tgtataacct gctatttaaa acatactctt ttatatttat acagtaatgt ggtttaattt
    17581 tataaaatgt aatctctact ggtaaaagac tttgtatata aggcatttgc ctgaataaac
    17641 catttatctt ttgtatggca tagatattgc tatatagaag tatatagtat gaaaggagat
    17701 atttatatgg gagataaaat gagagcatca gtattgtata atgtaggtga tgtcagatat
    17761 gaaatggtag atataccaga aataacagat acgcaagtgc ttgtaaatgt aaaatatgtt
    17821 gggatatgtg gttcagattt acctaggtct atggtaagtg gtttgagtgg aaatacaaaa
    17881 tatccattga ttttagggca tgaattttct ggtgaagttg ttaaaattgg agaaaaagta
    17941 aagcatatta atgtaggaga tagagtagct gttgcaccat tagtaccttg tggaaaatgt
    18001 gattattgta atgaaggtaa ttttggcttg tgtgatgatt acaatataat tggaacaaga
    18061 gtaaatggag cgtttgcaga atatgtaaga gttccagaag aacatatttt aaaactacca
    18121 gatacattgg attatgaaac tgctgccgga attgaaccag caactatagc ttatcatggg
    18181 atttcaaagt ctaatattag agtaggagat agtgtagttg tgttaggatg tggtccaata
    18241 ggtcagtttg ttatacaatg ggcaaaggtg tttggtgcat ctaagattat agcagttgat
    18301 atttttgatg aaaaattaga actttctaaa cttctaggag caaactatat acttaactca
    18361 aaagaagtaa atgtaatcaa agaaataaaa aaaataacaa atggtggtgc tgatgttgta
    18421 atagaaactg ctggtagccg atttacacaa gaacaatctc tatttgtagc aaaaaagaga
    18481 ggaaatatag tgtttgtagg tatatcacac acagaattac cacttagtgc agacgctact
    18541 gagtgtatat tacgtggaga acttaccttg aaaggttctt ggaattcata tacaagccct
    18601 tatcctggaa gagcatggac tgcaacattg gattttatgg aaaaaggtga cattattttt
    18661 aaacccatga tttcagataa aataggtctt aatgaagtgg gtgacttttt aagtaaaatg
    18721 agcaagagag aaattaattt caataaaatc ctagtagaaa tgtaaaaatt taataaaaaa
    18781 ttctaaaagc aattaaattt tataactata acattaaata aaataaaaat aattttctta
    18841 aataaaatat aggaggaaga aaagtgttag aaaatttaaa agaagaagta ttaaaagcaa
    18901 acttagaatt acctaagaaa aagctaatta cttatacttg gggaaatgta agtgggatag
    18961 atagagaaaa aggattagtg gtgataaagc caagtggtgt agagtatagt aatatgactg
    19021 tagaagatat ggttgtagtt gatttagagg gaaatatagt tgatggcaaa ttaagacctt
    19081 cttcagatac cccgactcat ctagttttat ataaagagtt tgaagaattg gggggaatag
    19141 tacatacaca ttcaagttgg gcaacaattt gggctcaaat aggaaaatct ataccatctt
    19201 gtggtactac tcatgcagat tatttttatg gaagtatacc atgtaccaga aaaatgacta
    19261 gagaagaaat ttgcaatgaa tacgaaaagg aaactggaaa tgtaatcatt gaagaattta
    19321 tgggaagaaa tccaattcat tgtccaggaa taattgtaaa tgaccacgga ccttttacat
    19381 ggggaaaaga tgcaaatgag gctgtacaca atgcagtagt tttagaagaa gtcgcaaaga
    19441 tggcttatta tacagagtta atgagtcctg ataatattat ggataaggtt cttatgaata
    19501 aacatttttc aagaaaacat ggaaaaaatg catactatgg tcaaaaatga ttatctggag
    19561 gtgaattatg ctagactctt taaaaggtaa agttgtggaa atagcaatta aagcagagca
    19621 ttatggttta tgtaaagaaa agactggtaa ttttagtatt agagataagg atactggata
    19681 tatacttata accccatcag gtgtaggaag agaagaatta aaagttgaac atatttgtgt
    19741 attggatttg gatggaaatg taatagaagt tgagaaaggt attaagccaa gtagtgaggt
    19801 attgatgcat attgaaatat acaaaacaag agaaaatata aatgccatat cacatactca
    19861 ttctttatat gcaacagcat tttcagtagc aaagaaacca attataccaa ttgtatatga
    19921 atcagttaat tatggcggtt atgtagatat tgcttcatac gaaagaccag gaactttaaa
    19981 attagctaag agtgtttcaa aattactgat agatacagat gcatgcttat tagaaagaca
    20041 tgggttgaca actgtaggta atgatttaga cgaagcatta ttaaaatcaa gatatgtgga
    20101 agaggtagca gaaatatact ataggtcttt agtattaaat caatttaaag aacttgaagt
    20161 agtagatgtt gatgagttta aatcttggaa atacccagaa gaaataaagt tttaatctaa
    20221 ataattttca ttgaagtggt taattaaaat atatgtatta tttatatcaa ttactatgtt
    20281 ttattatatt aattaccgta ttttgtaaat atatttatta cattttttca aaaaaatata
    20341 gaatccaaaa gccatataaa attgacttgg gattctatac tttttattta tgcatttttc
    20401 tttatctgat tttctggaga atttatatgt tcaaaatatt ttttagtttc agatactatt
    20461 ataggtgata atgcaagtaa agctataagg ttaggtattg ccataagccc atttacaata
    20521 tcagcaatta tccaaacaac ttctaacttt aagaaagcac ctaataacac catagccaca
    20581 aatacagttc tatacccatt catgcctttt acaccaaaca gaaattcaaa acatctttct
    20641 ccataataac tccatcccaa aattgtagta aatgcaaata atgttaaact aattgtaagt
    20701 aatattggtc caaatgtagg aattgctccg ttaaaagctg cttgtgtcat aacagctcca
    20761 tttaggtctg aacaccacac tcctgaaata acaagagaga atccagtaag agtacagatt
    20821 ataatagtat ctataaaagt acctgtcata gatataagac cttgttccgc tggccattca
    20881 gttttagcag cagctgcagc tattggagca ctacctagac cagactcatt tgaaaataca
    20941 ccacgagcga taccatttct aattgccagt gacatagttg ctcctaaaaa accaccagta
    21001 gcagcagtag gtgtaaatgc acttttaatt attaacataa aagtttcagg gattttattc
    21061 caaaaagata ttaaaatgat tccacagatt acaacatata taactgccat aaaaggtact
    21121 attttagtag ctacattaga tatactttta agtcctccaa atacaactaa agctacaaat
    21181 actgctaata caacccctgt aattctaggg tctatcccga aactattatt tattgcatct
    21241 gttattgaat ttacttgagt aaaagtaccg attcctaaaa gtgcaactag tataccactt
    21301 atagcgaaaa atattgcaag aggtctccat ttttctccca taccatttac tatgtaatac
    21361 attggcccac cagacacttg accattttta tctttagttc tgtattttat tgcaagaaca
    21421 ccttctgaat acttagtagc cattccaaag aatgctgcta tccacatcca aaaaagtgca
    21481 ccaggtccac cagctttgat agctgtagca acaccaacaa tattaccagt accaactgta
    21541 gcagctagag cagtacataa ggctgcaaaa cttgaaacat caccactacc tttgttttca
    21601 gcagagaata ttaacttaag agctcttggc agtttagtta tttgaacaac tccaagctta
    21661 acagtaagta gtataccagt accaactaat agtaccagta ggggtggtcc ccaaataaaa
    21721 gcatcaactt tgtttaaaat atcaattaga ttcataaaaa cactccctca ttttttttgc
    21781 tttacataat caatagaatt tttaatgaag taattgacag gaaataagta taatttatta
    21841 ataatttcta gtgtaataaa aaaagctaaa tctaaaaaag attcagctct ggatgtacac
    21901 taattagcaa ccaaaataaa agtattagta aatactgttt ttggtagata atccctgtcc
    21961 ttttgcctga gagattgagc ataaaagcct tgccccttcg gcgcccataa tgggtctctc
    22021 cagagttccg taaattttac agtcctactt ttaaaagtac ctgagagtgt tactccttcg
    22081 gtgtgctata tagcaactct tctataaaat cttaaccgga tattgatttg tcatagctta
    22141 ttgtattaat aatattaata taagttttta tgttttgtca actaaaaaat taaaaaacaa
    22201 agaaaaaata taaaaatgta agcctattta cgaattataa acttagaaag atgagtaata
    22261 tacgtgaaaa tgaattttgt aatacacata caaatgaagt gtaaaataag ttttaaataa
    22321 aaaaataata aaatcttaaa taattaatta gatatgatta aattatggta atattatagt
    22381 tacgatatta agaaaagttc tatttagtta gattttaagc gtaatatgag attatgtata
    22441 gagaaaggat gtatttttag atgggaaaaa tattagtgct agcagaaaaa ccttctgttg
    22501 gaagagatat agcaaaagtt ttagggtcaa aaaatgaaaa aaatggttat atagaggggc
    22561 caaagtatgt gataacttgg gcactaggtc atttggttac acttgctgac cccgaaagtt
    22621 atggagaaag atataaatca tggagcttag aagacctgcc aatacttccc aagcacctta
    22681 agactgttgt aataaaaaag agtggaaagc agtttaatac agttaaatcg caaatgaata
    22741 gaaatgatat agatgaaata gttatagcaa cagatgcagg tcgtgaagga gaacttgtag
    22801 caaggtggat aatagaaaaa tcacaggtaa aaaaacctat aaaacgtctt tggatttctt
    22861 caagtacaga caaagcaata aaagacggat ttgcaaaatt aaaaagtgga aaagaatatg
    22921 aaaatttgta ttactcagca atagcacgag cagaagctga ttggattatt ggaataaatg
    22981 caaccagagc tttgacaaca aagtacaatg cacagctttc ttgtggaaga gtacaaactc
    23041 ctactcttgc aatgttgctt aaaagagaag aagaaataag aaatttcaaa cctaaagagt
    23101 attatggatt agaattaatt gctacaaagg gaaattcaga tataaaattt atttggaatg
    23161 ataaaaacaa taattcttca acttttagta aagaaaagat agaatccaca ttaaaaaaag
    23221 taaaaggtgt agacataaaa atatctgaag taaacaagtc atataagaaa aaatattcac
    23281 ctgcactcta tgatttaaca gaattacaaa gagatgcaaa taaaatgttt ggattttcag
    23341 caaaagaaac tttatctata atgcaaaaac tgtatgaaca tcataaagta cttacttatc
    23401 ctagaactga ttctagatat ttaacatcag atattgttgg aacattaaaa gatagaataa
    23461 aagctgtaaa tattagtgat tattcaaaga tttgtaatag attattaaaa agcaatatta
    23521 tagctaataa atcgtttgtt gacaattcaa aggtaacaga ccatcatgca ataataccaa
    23581 cagaacagaa ggtattcatg agtgatttta gtgataaaga gcgaaaaata tataatcttg
    23641 tagtaaaaag atttttagca gtactatctc ctccttttga atatgagcag acaactataa
    23701 gtgcaactgt agaaggagaa atatttaagg ctaagggaaa caaagtaata aatttaggtt
    23761 ggaaagaaag ttataaagat attgaagatg aagatgagta tgaaagtata ccaaatgttt
    23821 tagaaaaaga tgtacttaag gtcaagggat taaagataac ttcaggaaaa acaaatccac
    23881 caccatactt aaatgaggga acattattga ctgctatgga aaagaatggt ctagggacag
    23941 ttgctacaag agcagatata atagaaaaat tattcaattc atttttaatg gaaaagaaaa
    24001 ataaagatat atatataaca tcaaaaggaa gacaattatt agatttagtt ccagtagact
    24061 taaagacacc agaacttaca gcttcatggg aaaagaaatt attggatatt tcaaagggaa
    24121 aacttagtaa aaatacattc ataaatgaca tgaaagatta ttcaaaagat attgtactag
    24181 aagtaaaaaa tagtgataat aaatttaaac atgataactt aactaaaaat agatgtccag
    24241 aatgtggaaa atttatgtta gaggtaaatg gtaaaaaagg taagatgttg atttgtgaag
    24301 atagagaatg taatactaga aaaactatat cacaagtaac caattcaaga tgtcctaact
    24361 gtcataaaaa attagaactt cgtggagaag gtgaggggag aatcttcact tgtagttgtg
    24421 gatacagaga aaagttgtct tctttcaaca agagaaagca agaagaaaaa cagaaggcat
    24481 caaaaaaaga tgttaatcaa tatttaaaaa atcaaaataa aaatcaagag acatttaata
    24541 atccatttgc agaagcatta gctaagctaa aaaacaaata attttaaagt tattattata
    24601 cacaattata actttaactg tatattagtt atatgtactg atataatata gtgtatagtt
    24661 taggcatgaa agtagggctg ttaaatggat ttaagtggca tatttaaata ctattgtaaa
    24721 gagtgtgaaa atacatggaa taattcgagt gttgaattat ttgagaatat agaaacgtat
    24781 agtaaagatt cacaaaaaaa gagggaaaaa gaattagata aattgctaaa tacaatatca
    24841 gttcatttag agaggtatcc aagtgatgct gtattgagaa aaatgtgggt aaaaaagggc
    24901 gaggttttct tacaaaagac attggaaaaa gaaaatattt ttaagttaga aaaaatggat
    24961 gtagaggata gaaaaaaatt tttagatata acaaaacagt ttattagaga tgctagaaaa
    25021 tttgatgatg atttacctat aggtgatatt atgcaagcta tgaggaatgt atggatttca
    25081 aatgcattac aattattatt tggtaaagaa gtatattatt caaaagctaa ctttgcatat
    25141 agtatgttat atccatatac tgataattat ttagacaata caaatataga taaaaatgat
    25201 aagattttat ttaataactg gttagaaaaa aggctcctgg gagaacacat taaatctaag
    25261 gattatcatg aaagtaaagt atctcaaatg atagattata ttgaaagtgt ataccctaga
    25321 gaaaagttta cagaagttta tgaatcgtta ttattaatat ttaaaagtca agtaaatagt
    25381 ttaaaacaac atggtaagga aaatcatttg tgtaaagaag atttattatc catttctatt
    25441 gaaaaaggag gttcatccgt tttagtagat ggatatttaa taagtggatt gatgacaaag
    25501 gaagaaatag agttttgtat aggatatgga tttttattac aaatatctga tgatttacaa
    25561 gatataaaag aagatttaaa atacaaccat aaaactatta ttacagagat gtcaaaagag
    25621 ggtactttag ataaagttgt aaataaacta ataaatttta ctattgagtt aatagatagt
    25681 tttaaaatta ataataaaaa taaatctgta ataactatga taaagaatga ttgcttaatg
    25741 ttaattttat tttctgtagt ttataatgct gaattttttt ctgtaggata tataaaagaa
    25801 gtagagaaat ttattccata tacaatagat tattcattag agattgaaga aaaaataaaa
    25861 gaaaaattta aaaatataga tgttttaaat aatgaaaatg aatataaaga aatgattgat
    25921 attatttgtg cagagtagaa aaaaagggag tgtcttagaa tagacttttt agtttatgag
    25981 gcactctttt tgtataaaat caaatgtatt ttcatcattt taataattaa aaagagctta
    26041 tccctatttg agaaagccct ttttaattta aataaaaatg tcaaggttaa actatttaaa
    26101 tgcagtaata atcccattat catgtaagtt ttttatgatt gtagctgcga tagggaatcc
    26161 aaataatcca gctattccaa atagttgagc tccaacaaac atacacatta atgttattaa
    26221 aggatatagg ccaatttggt gtcctactac ctttggttct aatatttgtc taacaacggt
    26281 tataattatg tatagtatta aaagtcctat tgctaaatta atatttccat taatgagtga
    26341 gataatcatc caaggtgtca aaatacttcc tgtacccaag actggcaaaa tatcaacaag
    26401 tgctatgatg acagatatag taaatgcatt ttcaaccttt aggatagtaa gtccaataag
    26461 tagttctatg aatgtcactg atagtagtat tgcataggct tttagtagtt ttaaaagagc
    26521 attaatactg ctatttttta tatttattat cataaattga cttttttctg gaaattgttt
    26581 taagataaag tttactattt tttgatagtc aaaagtaaag aaaaaagaag caattaaagt
    26641 aataataagt tttaacataa atgcaggtgt tttacttgca atactagcaa tagcattgag
    26701 tgcatttgtt gaaatagaag ctactaaaga catcatagat tgacttatat tatcccaacc
    26761 aagtattaat gctaggttaa cattaggtgt actagcatct atctttgaaa ataaagtatt
    26821 tagcgttggt tgtatacttg atttatatat ttcaggaagt ctaaaaaata catcacttac
    26881 acttgcaaat atcttcacac caaagctaac taataaaaat atacacaacc cataaaaaat
    26941 taaaagtatt actatagaaa taagtgtacg atttaaattt gtattatttg taataagtct
    27001 tataataggt cttaagatgg atgcaatgat aaaactgatt acaaaaggca ttaataatgg
    27061 caataagaat tttaatacaa tatatacaat acttgttatt aaaactacat atgtaaattt
    27121 aattataaaa ttcttttgct tttgaatatc cataatataa aacctccaat gtatttgata
    27181 ttattctaaa tatggtcttt tttacagaaa atatactact gtatattgat tataaactat
    27241 aaagcttatg taaagtaaat aaattatgta aaatttaggt taattttgta taaagagata
    27301 cttttatatt ttacaattaa taaccaaata ctaaaaaata ttttaaataa agaacttaaa
    27361 attgtgataa aattaattta tagatattaa aaaaagtata atatatggtt tttaagaggt
    27421 gctaagatga aaaattttag agatttaggt gggaacaaaa ctgaggatgg cagaactgta
    27481 aagaagggat tattttatag gtctgcaaaa ttatcaaatc taagtgaaaa tgatataaag
    27541 attttaaaag agttaaatat taaatatata tttgattata gaagtgatga agaagctcgt
    27601 aaacatccat caacaataat atcaaatata aaaaatataa gaataccagc aatgagagag
    27661 ctagaagaat caggaggaag ttttggttct attgaagata tgattgatgg attgtttgaa
    27721 aaagatggtg catttaatat gttaaataat agttactata atttgcctat aaataatccg
    27781 tcatataaaa aattagtaga acttataaga gactattcta atttaccaat attaaatcat
    27841 tgtacagctg gtaaggatag aactggtgtg gggagtgcta taattcttat gattttaggg
    27901 gtatcgagag agaatataat gaaagattat ctaaaaagta atgattttgc agataaagag
    27961 atagaaagat ttatagaata taagcctaaa tttaaggaca ttccaaaaga aaatttgaaa
    28021 tatatatttg gtgtaaatga agagtatatg aaaactgcat ttagaagaat tgatgaagaa
    28081 tacattagtg tagaagcata tttatatgga gaatttaatt taaataaaga agaaataaga
    28141 aaattaagaa atcaatatct agagtaaaag gtgagtttat gagtttaaat ataacagcaa
    28201 gacagataaa tataataaaa atattgttaa attcaaaaga tacaattagt ggtattgcct
    28261 taagtcaaga gataggatgt tcttcaaaaa ctatacaaaa tgaaataaag gatattaata
    28321 aacaacttag aaatggtaaa attttgtcaa taagaggagt tggttataaa ctagaaggaa
    28381 gttttgatga ggtaaatcta aatagcaatc tctatgatga tgtagataga gtagaatata
    28441 taatcagaaa aatattaacc ttaagtaatg aagaaaaaaa tactataaaa cttgaagatt
    28501 tagccgattc tatgtatgta agtgtttcaa cagtaaaaaa tgatttaaaa gaagtaaaaa
    28561 gaatattgga aaagtattca atatcagtta aatctaagca taaacaaggt atatgtgttt
    28621 tggaaagtga agataagata ttaaattgta tagttgactt aagcaataag agagataatc
    28681 aattgagttt aaatgatttt ttaaatgatg atataaagga aagaaaacta ttaataaaaa
    28741 aattattatt agacatatta aatgaaaatg gattggtatt aactgatata gaatttaaga
    28801 gtgtgttaaa taatatatta gttatgttaa gcagacataa gtataatgaa aaagaattta
    28861 tagagaatta tatagaaaat tataggagca aaagaagctc aattttagaa aatgaacaaa
    28921 acaaagaaat tataataaat tcaataaaaa cattttgtaa aaatttaaaa ttagctacat
    28981 caatagatat aagtaatgat aaggtatttg aagagttttt atataagcat attagtagtt
    29041 tatgtaaaaa aataaagtta ggtataaatc aatcacctat aatggctcaa gatataaaaa
    29101 taaaatatcc atttgctttt gaactagcta atatagctaa aaagacaata gaaaaagatt
    29161 tgaagataga aattaatgaa gatgaagttg caaacatagc cctacatata ggaggagcag
    29221 ttgaaagagc atcttataat aataaagata aggttttcaa aactataata gtttgtactt
    29281 caggcatagg cacatcaatg ttaataaaag ctaaattaga gaatatattt aaggaaaaat
    29341 tagaaatact aaagattatt ccttcatact tagttgaata tataaaagtt atagatgttg
    29401 attttgtaat atctactgtt cctattgaag taggagatgt gccagtaata aatatatctc
    29461 caattttaag tgagaaagaa attagattaa ttgaaaaata tatagaaaca ggaaatatat
    29521 acctagattt agatataaaa agcctgtttg atagtgaatt gttttttact gatttggtgt
    29581 ttaaaaggaa agaagaagtt atagatttta tggcaagtaa acttgtacaa aagggctata
    29641 tagatgagga tatgaaaaaa tcttactttg agagagaaaa aatagcaaca acagaaatag
    29701 ggaatatggt aactatacca catggagcta ttggaaaaat ttttgataat aaaatagcaa
    29761 ttggtatatt aaagaagcct atttcttggg aaatatcaga tgttcgttta ataataatgt
    29821 tagcccttga taaagataaa atattagatt atgaagtaat attttcaaaa atatataaaa
    29881 gagtagattc tatagcaaaa gttataagta tatgtgaaaa tagtagtttt gaaaaatttg
    29941 taaatttatt taattagatg ggtagtattg tatatacacc tgtaaatttg gataatataa
    30001 aactaaataa gataaaaacg ataaatttct cttttaatta agagaaattt tttgactttc
    30061 aaggatatta atataaagtt aagatataaa cataaagcaa ataaataaaa aagaggtggc
    30121 aatatgattt atacagtgac attaaatcca tcaatagatt atatagttaa gctagatgag
    30181 ctaaagacag gaagtacaaa tcgtgtaaaa gaagaatacg tttatccagg aggaaaaggt
    30241 ataaatgtat ctcgcatact taaggaactt ggaaatgata acacatcttt aggttttata
    30301 agtggtttta ctggagaata tataataaga acattggaag aaaaagaatt gaagacagat
    30361 tttataaaga taaaaagtgg tttttcaaga ataaatgtaa aaataaaggc gttaaaggaa
    30421 actgagatta atggacaagg tccaaatata gatgatgaag acattgatac tttatataaa
    30481 aaacttgata agctaaatca agatgatatt ttaatattgg caggaagtat accatctact
    30541 ttagatgaaa aactatacga aaatataatg gctagattag aaaaaaagaa tataaaagtt
    30601 gtagtagatg caactaaaaa tcttcttctt aatgttttaa aatacaaacc ttttctaatt
    30661 aagcctaata acgacgaatt agaagaacta tttggtgtta aattaaattc aattgaagac
    30721 atggtaaaat atgctagaag gttaaaggaa atgggagcta taaatgtctt ggtatcaatg
    30781 ggaaaaggtg gagcattgtt gattacagag gaagaagaag tgcttataag tgatgttcca
    30841 aaaggaaaag taaaaaattc tgtaggagca ggtgattcaa tggtagcagg atttatatct
    30901 gggtatttga atactgggaa atatgattat gctcttaaat tgggagcagc ttcaggtagt
    30961 gcaactgctt tttcatatga cttagccaaa agagaataca ttgataaatt ggtaaatgag
    31021 atatctgtaa agaagtttta aaatattaaa aaatatatag aaaggtaatt aatatttatg
    31081 aaaattatag atttattaga tgaaaagtca attaagttaa atttaaattc aaaaaccaaa
    31141 tcagaagcaa tagaagaatt agtagatttg gtcgcaaata gtggaaattt aaatgataaa
    31201 gaaaactaca aaaaagcaat tttggctcgt gaagaaatga gtacaacagg aattggagaa
    31261 ggtgtagcta tacctcatgc taaaaattct tcagttacta aagcttgtat agcagcagca
    31321 gtgtcaaaag aaggtataga ttatgaatcg tttgacggaa gtttatcaaa tctatttttt
    31381 atgatagctg caccagacgg agctaacaat actcatcttg aagtattatc aagattatct
    31441 acaatactta tggatgaaga ctttagaaat aaacttataa attcaagctc tgaaaaagaa
    31501 tttaaggaaa taatagataa aaaggaaaga gaaaaattca gtgaagaata tcaagatgag
    31561 aaagttactg aaaaaaatat aatagatact aaagagaatg atgctaataa gtatcctaag
    31621 gttttagcag taacagcatg tccaactgga atagcacata catttatggc agctgaaagt
    31681 ttaaataaaa tggcagaaaa caaaggtgta tcaataaaag tagaaactaa tggttcagca
    31741 ggtgttaaaa ataagcttac aaaagatgaa atagaaaatg caacatgtat aatagtggca
    31801 gcagataaaa atgttgagat ggctagattt aatggcaaaa aagtcataaa aactaaggtg
    31861 gctgatggta tacacaaagc ggaagaactt atagacaagg ctgtaaatgg agatgctcca
    31921 atttaccatg gaggagatgg aagtcacaac gaatcaaatg aagaaagtga aagtggattt
    31981 agaaaagtat acaaacactt aatgaatggt gtatctaata tgttaccatt tgttattggt
    32041 ggagggatac ttatagcgat agccttttta cttgatgatt atactattaa cccttcaaac
    32101 tttggttcaa atacacctat agcagctttt tttaaaggaa taggagataa agcttttgga
    32161 tttatgttac ctgtacttgc tggatatata gcatactcta tatctgatag accagcgttt
    32221 gttgtaggat ttgtaggagg tgctctagca ggtgatggtg gttcaggatt tttaggtgca
    32281 ctacttgcag gttttatagc aggttattta gtagaagggc ttaagaaaat atttagtgta
    32341 ctaccagctt cattggaagg aataaaacca gtattgttat atcctttact tggaacactt
    32401 ttgatgggaa ttataatgac atttttagta atacctccag ttacagcaat taataatgca
    32461 atggttggat ttttaaatgg tttaggtgga acttcaaaaa tatttttagg attagtatta
    32521 ggtggaatga tggctgtgga tatgggtgga cctgtaaata aagcagcata tgtatttgga
    32581 gttgcatcac ttgaatcagg gcagtttgaa ataatggcag cagtaatggc tggtggtatg
    32641 gttccgccac ttgctatagc tcttgcaact acatttttta agaatagatt tactaaagaa
    32701 gaaagagatt ctggtaaagt taattatgta atgggattat catttgttac tgaaggagcg
    32761 ataccttttg cagctggaga cccacttcat gttataccag cttgtgttgg aggttcagca
    32821 gtggcaggag cacttagtat gttgttcaac gcagctcttc gtgcacctca tggaggagta
    32881 tttgttatac cagtggttac ccatccattt gcatatatat tagctatagc tgtaggcgct
    32941 ttggttggaa tgatgctttt agcattactt aaaaaaccat taaatcaaga agtatagcaa
    33001 ttaaaggata ttcaagaact taaaatatga tgttttataa aaattaatat attgctgaat
    33061 tattttaaaa taaggatttt atgaggctgt tatataacga tttgtaattg ttatcttgac
    33121 agtcttttat ttttatataa gtaaaataag tgtgttttgc tttatttgta tttaaattgt
    33181 tttcaagtta gaacataaag aaaattatat attattttaa tattcactcg aactataaaa
    33241 taatatttgt tgtatttttt tgtatataaa atatattgta atattaaaaa aataatagta
    33301 aactgattgc ataaaaatga tttttatata aaatttaagc agaagaataa atttctaacg
    33361 aaattggata tttcttctgt aaatacatat tcaaaaaaag aattataaga gtttagtcag
    33421 cagtcgtgta agtaataagg actttataaa tatagaaata taatgatatg agtataagta
    33481 gaaaaatttt atgattttta caattatttt ttataaaaaa gggaggttat gtttgttgaa
    33541 tttacaatca aaatgggtaa actttttaaa gccaacatat gtcagtgatg aaataaaaag
    33601 aaaaaaacta caagttataa tatttttttc tataacttat ggtttatctt attcactagg
    33661 tttattagca atatgtttta atcatttaat agattcagaa attttagctc aatttatgat
    33721 gatattgcca ttatcttcag tttctattgc aaaattttac acagagggaa gaaataatga
    33781 taaatataat ttttattcat cagtaatatt attttttatt atttactttt ttatatttat
    33841 tattgaatca ttaaagttaa taagtattaa tcaatttcaa ttaatgtatc ttatgttaat
    33901 tttaataagt agtttatgtg ttattgttta ttcttataaa ataacaagtt tatatatttt
    33961 taaaaatttt aagataggta ttttgctatt tttttacttt ttattttctc aaattatttt
    34021 tggattaata ataagtgata atcaatttga ttataagaat ttcttgaatt atattcttct
    34081 tcctataata tcattagtat acatttatcc ttttttatgt gaagagtatg gttggagatc
    34141 ttttttgcaa agtattttat ttgatagatt tggcaaaaaa ataggtattg taatggtagg
    34201 cacttgttgg agtttatggc acttaccttt acaatttaca ctatatagtc ctcaaactcc
    34261 aataattgga gctatagccc atttgatata tggtattgga ctttctatat ttttaggtta
    34321 tgtttatatg aaaactaaga acatatggtt ttgctctata atgcatgttc taattaatag
    34381 cttaggatta attttcaatg attctgaaat aattattaat taccatagta ttatacaaag
    34441 attgatattt atactattat tttatactcc ttttctattt acaaaagaat ataagtaaga
    34501 attacaatta atttatataa aataaatttt taagtaaata tttttataga gagattgcta
    34561 tattacatat cagaaaaata ttaaactaac taaatcaata aaaaagttgg tggctaacag
    34621 tttataattg ttagcacaac atcatcttat gtattgaaat ctaaaatatc ctcattttta
    34681 cttagcataa atactattaa ttaagaaaat aatatagaaa ttataaatat atataagttt
    34741 agtctggtgt ataaaacaag aaaactaagt gatttttaat ttagcttttt attaagctta
    34801 ttttttatac tatttataat aaataaactc catgatggga aaactattac tatttaatat
    34861 gtaaaggagt attttaaatg aatgaatcat attggttttt aaactcaagt ccaaaagaat
    34921 ataacaaatt aggtgaaaat ataaaaacag attgtcttat agtaggtggt ggaataactg
    34981 gattgacaac tgcatattta ttagcaaaag aaggtaaaaa agtagtgctt gttgaggctg
    35041 ataaaatagg atatggaact tctggaagga atactggtaa ggtaacttgt cagcatgata
    35101 tattttactc taagatagag aaaaaatatg gattagataa agcaaaatca tattataatg
    35161 caaataatga agctttaaat ttagttaaac aaataataga agaaaacaat ataaaatgtg
    35221 attttaaaag ggaaacttct tttgtattta cagaaaaaga ggatactata aagaatatta
    35281 aagatgaata tcgtacatgt aaaaaaatag gaataaattg tgagtatcat gaaactatag
    35341 aaaatattcc attagatata aagggggcta ttagttttac taatcaaggt caatttaacc
    35401 caaagaagta tattgatgga ttggcaaaag cagcagtaaa tttagggcta aaaatatatg
    35461 aaaatacacc agtagtagac cttgaaaaag gaaaaatatg tagggttaaa acaagagaag
    35521 ataatataat agaagctgag aatgttataa tttcatctca tagtccatgg tatgatggat
    35581 tgaattttta ttttgcaaaa gaatatgcag agcgtgctta tttaatggtt gcagttttgg
    35641 aaaataaatt agcagatggt atgtttataa gtatagatga cccatcaata acttttagac
    35701 aatataatga tggaagtgaa aatttactga tttttggagg aggagaccat aaagttggtc
    35761 agggaggaac tgagaaagaa atatttgatg atttagagca ttatggtaaa gaagtcttta
    35821 aggtaaaaga ttttaagggg aaatggtctg ctcaagataa tatgagtttt gacaatgttc
    35881 cttatattgg ttatatcaac aaaagagaag acaatattta tgtagctaca gggttctcta
    35941 aatggggaat tactaatgga actgctgctg gaataataat aaaagattta ataataaata
    36001 ataattctga ttataaagat acttttaatc catccagact aggtagctac ttttcaaaag
    36061 attttataaa ggaaaatgca aacgtagcaa taaattatgt aagtgggaaa ttaaaaatag
    36121 gtagtggaga tatgcctaaa aataatggag aaggaaagat tgttaatatt gatggaaaaa
    36181 gatatggtgt atataaggat gataatggag atttttatat tgtagacact acatgtactc
    36241 atttaggatg tgaacttaat tttaacagtg aagaaaaaac atgggactgt ccatgtcatg
    36301 gttctagatt tgactataag ggaaatatac ttgaaggacc agctcttaag ccattaaaac
    36361 tttatggaca tggtgataat gatgttaatc ctaagttatt ataaaattat ttttaggaag
    36421 gtaaagtgta tatgaataaa cttttaaagc caataactat actattgtat atagtttata
    36481 ttttatctgc cgtatttttt gtagcaaaca aagaatatgg aagtctaggt ctagtagcaa
    36541 ttagtttagt tggtactttc attttgagtt ttataaataa gcaaactgaa agattattga
    36601 gtaaagaatt atatataatg cttgctttat ttataatgtt ttcatcattg ttaggtactt
    36661 gttttaattt ttatgatata aattattatg atgatttttt gcatttatgg tcaggtataa
    36721 tatcttgtat tgtggctttt tctataatta aatactttta tacacaaaga gagataagta
    36781 aaatgagtaa agtgttttta gttatatttt tatttatgtt tagtatggga gtagcgagtt
    36841 tatgggaaat aggtgaattt ttaatggata cttttgttgg gactactaca caggccggag
    36901 ggttagaaga tactatgatt gatatggtag atgctttaat aggtacaatt ataactattc
    36961 cttttatagt aaaaaaatct aatatatagt tttaaatttt ttatattaat tataatggat
    37021 ttaattaatc atgttgagtt tcaaggtcta tatgattaat taaatccatt tttgttattt
    37081 ataattatta ttgaatatat ttttacatat aagatataag gtgatagata gaaattgttg
    37141 gattatgtaa ataattaata tataatacca ttatgggcaa taaatacaaa tcaaatgata
    37201 atatagtcta tttatgtaaa tgttaaattg tatcctaagt ataatagtaa gttttttgat
    37261 agtggtgtag aaagtaaaaa tctactagcc taaattgatg tatggattag tttaggaaca
    37321 gtaattgcat atcttaagtt tgatgtcatg ttgggctact agaaataggt catctttttc
    37381 acttgaatat cttttcttta aacatgggga gtatcatatc aaaaacatat gaaaattaag
    37441 tgatttatga gaacagtaat attttatatg atagtataga atagtaataa agtattagga
    37501 ggaacattga gtgttaaaaa agtggtttgg tattgtgaaa aaaagacaaa aaagtgagtc
    37561 agtaaaagaa gaaggtgaag taatattaaa aaacgaaaaa atattatctg aagaaaagtt
    37621 gatagatgaa gaaggagttg tagttaatat tgataatgaa atattaacta aagtagaagt
    37681 agtaaatgat gacaatgaaa tagaagaaaa aataatagaa gaagattggt taattagtga
    37741 aaataccata aaattagatg ataaagaagc aattattaat gataaaaaca tagaattatg
    37801 taaaaaagaa gttcaagttg aaggtgaaaa aatagattta aataagtttg aaggacttga
    37861 ccaaaatgaa aattataatc tagaaaaaaa tgttattgaa gaaaaagaag taagtgaatg
    37921 tttgacagaa gaagatttag agtacataaa agaaattaaa ataaaaagag gaaaaagtat
    37981 aaaagctata aacttgtata ctaaagaaga gtgggttttt gacactcata tacagtgtag
    38041 taaaaaactc aaagttccat tagggtacat aagagaaaat ttaaaatatg gatatatgga
    38101 ttactttgga gatgcaataa attatttaag tgaagtatta aatatagatg aatactgcaa
    38161 aagtgaatgg agctatctcg ataatagcaa atctccatct gagatattta atattctaaa
    38221 caataaaata tttagtataa ggctttctaa tgaaaaaaga aatgaaattt tgacaaatga
    38281 taaaattgaa gcattaaaaa tgaattatag atttgaatgt attgatgaag aatatgatga
    38341 atattttaaa aaatataagt ctataatcaa aagaggtgga aagaaaaaag ttgaattagt
    38401 aaataaaaaa ggtgacattt tagaaatatt taagtcttta gaagaatgtg ccatttattt
    38461 gcaaaaggaa aagaatgaag ttatacaaat gttaaaatat ggagatacaa aagtaggaag
    38521 aaactttata aggtatagtt tgagaagtat ttaatttcat tttaaattca taagagtttc
    38581 atttctgatt cacacattta atattatttt aatgtaaaat aataaaggtg aagtattgta
    38641 caattaaaat taaggagggt attaatgtct gaagaaaaaa atccaaaaga aaatacatta
    38701 gatgaatcta aaaattcaga taatgtaaat tctaaaaaag atgatgtgtc agatgaaaaa
    38761 aatactgata acaaagttaa aaaaagggaa ataaagctaa acaacaaaac acttaaagct
    38821 attgtagcaa ttgttgcagt aggagctata tgtttaggtg gaggctatat ttttggcaaa
    38881 gaagctggaa gaaaattgcc tgctacttca aaacactata atagcagtga ggtagtagct
    38941 actattgggg ataaaaaaat aacaggtgaa atgttaagaa agagaatgga gccattattt
    39001 tatttaaatg caaaaactac tatgactgat gacgaaatac gttcatatga atcaaatatg
    39061 attgaaacta tgattacatc tgatatatta tcctctgaag cagcaaaaga gaaaataagt
    39121 ataactaatg accaactaga tgctcagtat aataatttaa tgagtagtat agaatcagca
    39181 atgggaatga ctaaagaaga gtttttaaaa cagtttgatt tgactgaaaa atatataaaa
    39241 gatgatatga aaaaagagct agtagcatca aaatatttaa atgaaaaatc aaaagttact
    39301 gataaagaag cagagaacta ttacaataaa aacaagagca attatttaca agttagagct
    39361 tcacatattt taataaaaac tgttgatgat aaaggtaagc aagttagtag tagcaaaaaa
    39421 gctgaactta agaaagaagc tgaagaaata cttaaaaaag cccaagctgg ggaagatttt
    39481 gctactctag ctaaaaaata ctctgaagat agtagtgcag aatcaggtgg agatttaggt
    39541 ttctttggta aaggtcagat ggtggaatct tttgaaaaag cagcctttgc attgaagaag
    39601 ggagaggtat ctaacaaact tgtagaaagt gattatggat atcatataat taagaaaact
    39661 gatgaaaaat atcagccatt tgaagaggta aaatcagatt tagtaagcag tttaacatca
    39721 gaaaaacaaa acctacttat acaaaatcta aaagaaaaat ataatgttaa aattacagat
    39781 aaatatcaaa tgaaagctaa agaatagata aagtcaattt attaaaaaaa agaaaaatta
    39841 actgtatgga taaaagctat ttttactctc aatatagaga gtataaaata gcttttatta
    39901 ttttgcaata aaatctattt atatatatga agtgacaaag aaataacatg caaaaagaca
    39961 ttaaaaagaa atatttttaa tttgaatttt ttcaataaaa atttacaaaa atgaaaaaat
    40021 aaacaaaaaa gaattgaaga tttaagttgt ta
//
LOCUS       DAEOTL010000030        39837 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEOTL010000030 DAEOTL010000000
VERSION     DAEOTL010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.030"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            121..1179
                     /locus_tag="KRH82_001878"
     CDS             121..1179
                     /locus_tag="KRH82_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBG8655157.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            1430..3574
                     /gene="fdhF"
                     /locus_tag="KRH82_001879"
     CDS             1430..3574
                     /gene="fdhF"
                     /locus_tag="KRH82_001879"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1844..1846,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HBG8655158.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            3623..4456
                     /gene="fdhD"
                     /locus_tag="KRH82_001880"
     CDS             3623..4456
                     /gene="fdhD"
                     /locus_tag="KRH82_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBG8655159.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            4467..4640
                     /locus_tag="KRH82_001881"
     CDS             4467..4640
                     /locus_tag="KRH82_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655160.1"
                     /translation="MCTKKEEQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDENN"
     gene            4677..5228
                     /locus_tag="KRH82_001882"
     CDS             4677..5228
                     /locus_tag="KRH82_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8655161.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            5253..6629
                     /locus_tag="KRH82_001883"
     CDS             5253..6629
                     /locus_tag="KRH82_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBG8655162.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            6629..7144
                     /locus_tag="KRH82_001884"
     CDS             6629..7144
                     /locus_tag="KRH82_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8655163.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(7222..8505)
                     /locus_tag="KRH82_001885"
     CDS             complement(7222..8505)
                     /locus_tag="KRH82_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBG8655164.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     KISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            8693..9115
                     /locus_tag="KRH82_001886"
     CDS             8693..9115
                     /locus_tag="KRH82_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBG8655165.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            9217..10155
                     /locus_tag="KRH82_001887"
     CDS             9217..10155
                     /locus_tag="KRH82_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBG8655166.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            10341..12365
                     /gene="ligA"
                     /locus_tag="KRH82_001888"
     CDS             10341..12365
                     /gene="ligA"
                     /locus_tag="KRH82_001888"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBG8655167.1"
                     /translation="MSIKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKASDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            12525..13874
                     /gene="rph"
                     /locus_tag="KRH82_001889"
     CDS             12525..13874
                     /gene="rph"
                     /locus_tag="KRH82_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBG8655168.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEIADEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            13874..14344
                     /locus_tag="KRH82_001890"
     CDS             13874..14344
                     /locus_tag="KRH82_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8655169.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMNIEEDDIKIEEIRI"
     gene            14538..15824
                     /locus_tag="KRH82_001891"
     CDS             14538..15824
                     /locus_tag="KRH82_001891"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBG8655170.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRANLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            15974..16558
                     /gene="clpP"
                     /locus_tag="KRH82_001892"
     CDS             15974..16558
                     /gene="clpP"
                     /locus_tag="KRH82_001892"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBG8655171.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEIFSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            16577..17827
                     /gene="clpX"
                     /locus_tag="KRH82_001893"
     CDS             16577..17827
                     /gene="clpX"
                     /locus_tag="KRH82_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBG8655172.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(17898..18425)
                     /locus_tag="KRH82_001894"
     CDS             complement(17898..18425)
                     /locus_tag="KRH82_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBG8655173.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(18413..18925)
                     /locus_tag="KRH82_001895"
     CDS             complement(18413..18925)
                     /locus_tag="KRH82_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBG8655174.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            19105..21468
                     /gene="lon"
                     /locus_tag="KRH82_001896"
     CDS             19105..21468
                     /gene="lon"
                     /locus_tag="KRH82_001896"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBG8655175.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKESFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            21458..22069
                     /locus_tag="KRH82_001897"
     CDS             21458..22069
                     /locus_tag="KRH82_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBG8655176.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(22334..23704)
                     /locus_tag="KRH82_001898"
     CDS             complement(22334..23704)
                     /locus_tag="KRH82_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655177.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(23879..23994)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            24282..25361
                     /locus_tag="KRH82_001899"
     CDS             24282..25361
                     /locus_tag="KRH82_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8655178.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            25752..26432
                     /locus_tag="KRH82_001900"
     CDS             25752..26432
                     /locus_tag="KRH82_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBG8655179.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYNNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            26425..27804
                     /locus_tag="KRH82_001901"
     CDS             26425..27804
                     /locus_tag="KRH82_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBG8655180.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            27975..29060
                     /locus_tag="KRH82_001902"
     CDS             27975..29060
                     /locus_tag="KRH82_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBG8655181.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISIVVTNNLAYIIFSFILFSIGNIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVVDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            29114..29473
                     /locus_tag="KRH82_001903"
     CDS             29114..29473
                     /locus_tag="KRH82_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBG8655182.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            29526..30398
                     /locus_tag="KRH82_001904"
     CDS             29526..30398
                     /locus_tag="KRH82_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBG8655183.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            30399..30842
                     /locus_tag="KRH82_001905"
     CDS             30399..30842
                     /locus_tag="KRH82_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655184.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            30857..31441
                     /locus_tag="KRH82_001906"
     CDS             30857..31441
                     /locus_tag="KRH82_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655185.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            31694..32731
                     /locus_tag="KRH82_001907"
     CDS             31694..32731
                     /locus_tag="KRH82_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBG8655186.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            32812..33177
                     /locus_tag="KRH82_001908"
     CDS             32812..33177
                     /locus_tag="KRH82_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655187.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            33182..33499
                     /locus_tag="KRH82_001909"
     CDS             33182..33499
                     /locus_tag="KRH82_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655188.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            33547..35151
                     /locus_tag="KRH82_001910"
     CDS             33547..35151
                     /locus_tag="KRH82_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655189.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            35275..36903
                     /locus_tag="KRH82_001911"
     CDS             35275..36903
                     /locus_tag="KRH82_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBG8655190.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            37168..38517
                     /locus_tag="KRH82_001912"
     CDS             37168..38517
                     /locus_tag="KRH82_001912"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBG8655191.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSADKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            38673..39752
                     /locus_tag="KRH82_001913"
     CDS             38673..39752
                     /locus_tag="KRH82_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBG8655192.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
BASE COUNT        16380 a         4252 c         7161 g        12044 t
ORIGIN      
        1 ttaatatttt ttgtaaatga caaaattgta aggtattttg ttataaaata ttaagattca
       61 tagtgtatac taataatata gtatttagta taaatcttga gcaaaggatg gttatttcta
      121 atggatagac taaagaatat tagaaagagt ttactacagt atacattttt atttttgtta
      181 ataggtataa caatttacct agtgtttaaa acattggata ttaaaatgct atcaaatgtt
      241 atggttatgg tagataagaa gtttttattc ataggtgctt tggcaataat gtgtcacata
      301 atgcttgaag gagtagtaat gaagataatt atagaaagca ctcacaaagt taatattaga
      361 tttattggtt ttaagctagc cattatggga ttttattata atttaataac tccttttgct
      421 tcaggaagcc aaccagtaca gatatatgta cttaaaaaat gtaaaatgcc acttagtaag
      481 gcaagtgcag ttgttaccaa taagtctatt atcttccaaa tagtagttac tttttattgt
      541 acaatacttg ttttaatgaa ttttgctatg ttagaaaaac aaatgaaaat gattatgcct
      601 ctagtgtttc tagggatagc cattaattca tttgtcttaa ttatgataat attagttatt
      661 ttaaatccta aaaaaataaa atattttatg agaattacta taaagcattt atcaaaaatt
      721 aagtttttaa aatttttaga taataagatc gaatccatag aaagttttat agatgattat
      781 agtaaagcaa taaatttttt tgcaaagaat aaaaaggtat taatttcaac tataatagta
      841 acttttattc aattaagtgc ttactttagt gtttcatttt ggatatataa agcatttaat
      901 ttacaaggtt atagctatat ttatatactg acattacaag catttttata tatggcaata
      961 tctccaatac caacacctgg gaatgtagga gctaatgaat tagccttttt cactatattc
     1021 aaatcagtat tccctcaacc tttgatggga tatgcagtat ttttatatgg tggatttatg
     1081 tactatttga ttctgattgg aagtggaata tttactgtaa ttactcacta tagaatgaaa
     1141 aatagaattg gcagaaatat tgttttaagt gaaaactaaa taagtttaaa gaatatatat
     1201 tgagtatatt aaaaaatatg tcataagaac tagaatattt taattaaatg gttgaaatat
     1261 aaagattatt atgacatatt ttttttgaaa tttaagagga attgtgagaa aattgttgaa
     1321 tttaatagat agtattgcaa aatatttatg attttgcata ttataaaaac actcattatc
     1381 tttaagataa attttactta tcaggggata aatctaaggg gggaattgta tggagaaaaa
     1441 aattttaaca gtttgtccat actgtggagc tggatgccaa ttatatctag tagtaaaaga
     1501 taataagata ttaagagctg aaccggctaa tggtagaaca aatcaagaaa gtttgtgttt
     1561 aaaaggtcgt tatggatggg attttctaaa tgaccctaaa attctaacac ctaggctaaa
     1621 aaagccaatg ataagaaaac aaggtgtact agaagaggtt gaatgggatg aggctataaa
     1681 ctatacagct tcaagactaa atgaaattaa agaaaaatat ggacctgatt ctattatggg
     1741 aacaggttct gcaagaggac ctggtaatga agcaaactat ataatgcaaa aatttatgag
     1801 agctacaata ggaactaata atgttgacca ttgtgctcgt gtctgacatg caccatctgt
     1861 agccggtctg gcttactcat taggtagtgg tgcaatgtct aattctatac cagagataga
     1921 aaatgcagat gttttattta tatttggata taatggagca gattcacatc caatagtggc
     1981 aaatagaata gtaaaagcta aaaaaaatgg tgctaaatta attgttactg accctagagt
     2041 aactgaatct gcaagaattg ctgatataca tctacctata aaaggtggaa caaacatggt
     2101 tttagtaaat gcttttggaa atgtattaat agaagaaggt ctttacaata aagaatttgt
     2161 tcaaaatcat acacaaggat ttgatgagta taaagaaatt gttaaaccat atacagctaa
     2221 atatgctgaa aagattacag gaatcccaga agagcttata agaaaagcta tgagagaata
     2281 tgcaaaaggt aaaaaagcta tgatacttta tggaatgggt gtctgtcaat ttggtcaagc
     2341 tgttgatgta gttaagggac ttgcatcaat tgctctactt acaggtaatt ttggtagaga
     2401 aagcgttgga ataggacctg tacgtggaca aaataatgtt caaggagctt gtgatatggg
     2461 agctcttcct aatgtatatc ctggctatca aaatgtaact gatgataaga taagagaaaa
     2521 gtttgaaaaa gcttgggggg taaaattatc tcctaataat ggttatagtt taactcaagt
     2581 tccagactta gtactaaaag agaaaaagct taaagcttat tatatatttg gagaagaccc
     2641 agtgcaaagt gacccagatg catcagaagt tagagaagca ttagatgaat tggaatttgt
     2701 cattgttcaa gatatattta tgaataagac agcacttcat gctgatgtta tacttccagc
     2761 tacttcttgg ggagaacatg agggagtata tacatgtgca gatagaggat tccaattgat
     2821 gagaaaagct atagagccac aaggagatgt aaaaccagac tggcaaatta taagcgaaat
     2881 ttctacagca atgggatatc ctatgaacta taaaaatact aaggaaatat gggacgaact
     2941 tagacaatta tgtccaagtt tcttaggtgc tacttatgaa aagatagaaa ctcaaggatg
     3001 cgttcaatgg ccttgtaaga gtgaaagtat ggaagataaa ggaactatgt atctgtatga
     3061 aggtcaaaag ttttctactc ctaatggtaa aggtaatttg ttcgctgctg aatggagacc
     3121 ccctatggaa gttgaagatg atgaataccc atttagttta tgtactgtaa gagaagttgg
     3181 acactattca gtaagaacaa tgactggtaa ttgtagaaca cttagttcat tagaagatga
     3241 accaggacgt gttcaaataa attctaatga tgctgaaaaa ttaggaattg aagatgatga
     3301 attagttaga attagttcaa gaagaggaag tgtaataaca agagcaacag ttactgatag
     3361 agttaaggaa ggtgcaacat atatgactta tcagtggtgg gttggagctt gcaatgaact
     3421 tacaatagca aatttagacc ctatatctaa aacaccagag tataaatatt gtgctgttaa
     3481 acttgaaaaa cttgaagacc aagaattagc agaaaaatgt gtaagagaag agtatcaaag
     3541 tttgaaagac aaaatgacag ctacaaatat ctaatgattt attagattta agatttataa
     3601 aaggcagaaa ggctaatatt ttatgaacaa tatatactca aaaactaaat tacaagaaaa
     3661 tagtaaggat aaagtttttg aaaatagtta tagtctagtg gactacaaat atttaaattc
     3721 ttttaatgta gaagtaagca aaataaatga acatgaagta tcaatagata atgaagaaat
     3781 aattgcagaa tatccactta gttttatttt aaatgataaa tatataaata catttttatg
     3841 taccccatat aatttagagg aacttatagt aggattcttg aaaacaaaag gatacataga
     3901 aaacaaaaaa agcttattaa aatttgagat aaatgagagt gaacgttttg caaaagtaac
     3961 tattcaagag aaacaaaaaa atcaagatga gcaaattata tttttaaatt cactagacta
     4021 tataacatgt gctcctgtaa agagcaatat aaaaataaat tatgatacga tttacagtat
     4081 aatggataaa aatttaaatt catcagaatt atttaaaaat actggtgggg tacatagtgt
     4141 atctgtattt aattttgata aaaaaatagt cacttgtgaa gatgtagcaa ggcataatgc
     4201 aatggataag gctattggat tttgtgtttt aaatgacata acattaaaag ataaaattgt
     4261 ggctgtaagt ggaagaatat cattggaaat gatattaaaa gcagctatga ctcaaattcc
     4321 tattgtagta tcaaaatcag caccgactaa tttatcaata gagctttcta aaaaattaaa
     4381 tataacgctt attggatttg taagaggaag acggatgaat atttatgcaa atccacagag
     4441 agttatcaaa aagtgagaat gaatatatgt gtactaaaaa agaagagcaa agatattcaa
     4501 agtgtgaaat ctgtggagta ttaattgatg atactgataa ggtatataat aacacataca
     4561 atttgtgcaa aaaatgtaaa cgaaatataa gtactgagaa aatagtgaaa tatataaata
     4621 tatatgatga aaataactag agggttggaa atatacaaat tgaaaggtgg gataatatga
     4681 aaaataaaat aggctctttt gtaatagcag acccaaacaa atgtacaggt tgtagagctt
     4741 gtgaagtagc ttgttttaca atgcataatc agcataataa tgtgggttat acagttggaa
     4801 cagttgatat acctgttata cctagacttt acttagtaaa aggtgacaat ttctgtatgc
     4861 caatacagtg tagacattgt gaagatgctc cttgtttaaa ctcatgtcca caaaaagcta
     4921 tagttaaaga aaacaatatt atgtctgtaa atgaagaaaa gtgtatagga tgtaaaactt
     4981 gtctgctagc atgtcctttt ggagctatag acttacttcc acaatatgaa gatggtaaag
     5041 aagtagaaca agtaatttta gatgaaaata agaagatagc ttataaatgt gacttatgta
     5101 aagacaatga aaaaatagct tgtataagtg catgtcctca ggaagcatta aaacttgtta
     5161 ctccaataga tgacaaaaaa gctaagaata gacaagctgc acttagttta ttgttaacaa
     5221 ataaataaag gatacagggg taggtgacgt ttatgataat aaatatagat aaggatttat
     5281 gtactggatg tagagaatgt tcaaaggtct gtccagtaaa tgctattgaa ggtgaagagg
     5341 gaaagccaca agagataaat ttagatagat gtgttatgtg cggtcaatgt gttcaaactt
     5401 gtaaatctta tgcctcagtt atagatgaag gatttgagtt tttacaagag aaaaaacaag
     5461 aaagagagat accagagtct ataaatgaac ctatatttgc agcatacaat gtatgtgata
     5521 tagataaggt gaagaaagct ttaagtgacc caaatgtatt cactatggtc caatgtgcac
     5581 cagcagttag agttgcttta ggagaagatt tcggatatta tttaggatac ttaggtgctg
     5641 ggaaaatggc agcagcactt agagctttaa attttgatag agtctacgat actaattttg
     5701 cagcagattt aactataatg gaagaaggta gtgaattaat taaaagagtg acagaaggtg
     5761 gaactcttcc aatgtttaca tcttgttgtc cagcttgggt aaaattcatg gaaaaaaatt
     5821 atcctaaatt aactaatcat ttatcttctt gtaaatcacc tcagcagatg ggtggtgcaa
     5881 tatttaaaac ttatggtgca gagataaata atgtagatgc atcaaagata tttagtgttt
     5941 ctataatgcc atgtacatgt aaaaaatatg aatgtgatag agaagaaatg gattctagtg
     6001 gatatagaga tgtagatgta gtattaacta ctagagaact agcttattta ataaaagaca
     6061 tgggaattga ttttaaaaat ttaagagaag aaaaatttga tagtccttta ggtagttata
     6121 gtggagctgg aactatcttt ggtgttactg gtggggttat ggaagctgct ataagaacag
     6181 gatatgagct tataactgga gaaagtattc ctgatgtaga agtaaaacaa gtaagaggag
     6241 aaaatggttt tagaaagtca actattaaaa taggagactt agacttaaga gttggagtag
     6301 taagtggatt aaaaaatgta ataccagtgc ttgaagactt ggaaaaagga aaattagatg
     6361 tagattttat tgaagttatg acttgtcctg ttgggtgtgt aagtggtgga ggtcaaccaa
     6421 aaattttact agaagaatat aaggaattgg cttatgaaaa tagaacaaaa gcaacatacg
     6481 tgcatgatga acatttagca attagaaaat ctcatgagaa tcctgatatt aaaaaactgt
     6541 atgatgaata tctggtagaa ccattaggag aaaaatctca tcatctatta cacactacat
     6601 attgtatagg aaaggaagtg gctaagtgat gaactatttt gttatagcag accctgataa
     6661 atgcatagga tgtagaactt gtatgatagg atgtgtagtt gcacattcag atgaagatat
     6721 tttttaccaa aatccagatg aaataaattt taatccaaaa ctttctgtca taaagacaaa
     6781 agaagtaagt gctccaatac agtgtagaca ttgtgaagat gctccttgtg caaaggcatg
     6841 tccaaatggt ggtatagtta gggttggtaa cacaataaaa atcaatgaag aaaattgtat
     6901 aggatgtaag acttgtatgt tagcatgtcc tataggtgca atagacatag ttacattaaa
     6961 agatgtagat gaaggaaagc tttgctttag agaaagaatg acagcaaata agtgtgattt
     7021 ttgtatagaa tcgccagaag ggcctgcatg tgtaaatgtt tgtccaacta aggcatttac
     7081 tatagttaag gatgaggata tagatagtaa agttaaaaat aagagaaaat tagctatatt
     7141 gtaatataaa aaagatggag ttttatttat gattaaaagc tccatctttt ttattataat
     7201 atttatatat ctaaaaatca attattgcat tagtttatct aatctttctt tattcaattt
     7261 tttcattcct atagaagtta taataagtaa agtataggca attataactg ataaaattat
     7321 aatagaccaa gaaaatctgt atccaaaatt atcaactaac aatccaaata atgttgaacc
     7381 taatgcaaat cccactgcaa aaattaattg tacgattcca tatatgctac caaactcctt
     7441 ttgaccaaag aaagagccag ttaaataagc aggaccaatc atataagcaa atacagaaag
     7501 acctttcaaa atggcaaata caaatgcaaa agtagaagat ttatctacca atagtaatga
     7561 taaagttgct ataagaacca atacaaaaga tataataagt ggctttgttt gaccgaattt
     7621 atcaaacaat aatcctccaa ataaattacc aatgagagca aataaagcaa atgtggagcc
     7681 tactgttcct attagaatag gatttagata atttctaaga taagttggat attgtacaga
     7741 taatgatgaa acatatatac caacaaatat aaatccaata gtcataatcc aaaaatattt
     7801 aattttttta gcttctttta atgtataacc ccatactgaa ggagaaattt tatcagatgc
     7861 tttctctttt ttacctttag attttacctt ttcattaata tctttaggca tcctgagtat
     7921 aaataatatt acaggtatac caactattaa tgctataatt ccaaatatta gataagaacg
     7981 actgtatcct tgagttgcta ataagcgaac tgcaagtggt tgtagaaata tactaccaat
     8041 agaaccacca gcaaaagcaa agcccaaagc ttttcctttg ctttcttcat caaaccaagc
     8101 acttattaaa acaggtattc ctatagcaga tataattgta gcgccaattt gaacaataca
     8161 tgatacagtg taaaattgcc atagttcagt acatatagaa aaagtagcaa aagcaatact
     8221 agaaattata caacctaata aatatagtat cttaatattg actttagaaa ataatacacc
     8281 tataaaaggt gatgcaattg ctgaggcaat agtaccaata gtgaatatta gagaaaaaga
     8341 agctaaacta aagccttctc cttctacaac ataacttata aattgaggct gtatacttgc
     8401 tacaatacta aatggaacag cttgtattaa catacaacca agtactataa cccaagcatt
     8461 tgaaaagttt ttaatgctaa atttattgtt tagtaatgta ttcatggtat ctctccttta
     8521 ggttatgatt tgtagatatt aatctaatta ttctaatttt atatattagt tttggatagc
     8581 ctaactattt aaatataatt tgggtattaa tataaaaatt aactataaaa attgattatt
     8641 ttaaatgtat ggggtaaatt aaagtatata aataaatgaa aggatggata aaatgtcatt
     8701 tgaaaaaata aataataata acctagataa aatacacaac aggaagtgta ttatgcttgt
     8761 aaactttaat aaaaaagaat tatcattaat taaaaacgta agtaactttg ctggaataag
     8821 agaccatatc atcttaagtg ataaaaatgg agagaatata ataagagaca ttttagatgg
     8881 aaatatatca aatgaatgtg aaaatgggat taagagtaag tctgtaatat ttaataacac
     8941 tccaagcaca caagtaaatg catttttaga agggctaaaa aaagtgagaa taaatagacc
     9001 ttttacagct atggtaacag agacatctat tgattggaca ttgaataatt taatagaaaa
     9061 tttagttcaa gaacgtaatg ctatgtcttt aggaaaaaca attgaacata agtaaattta
     9121 agatatctta tagtaatttt aactaatgta cattgagtat catattatat tttagaatat
     9181 aaaattttaa atgtgggtag atggaggaga tttgagatga aagttttatt tacaataaat
     9241 tatggaaaag aaaaatttga taaaataaga gaattaggct atgatgtcat acattactct
     9301 gaagatagta ttgaaaataa tgaggatgta aatacagcag atgtactagt tacatacaat
     9361 ccatttgaga gattagatat ttctaagatg aaaaatttac aatatataca gacaactagt
     9421 gtaggtatag accaacttcc aaaagaagag gtattgaaga gaaatattaa gatagctaat
     9481 aatagaggcg gatatagtgt acctattggt gaaagtattg tattgtatat tttagaaata
     9541 tataaaaata gtgcaaaatt ttttaaacaa caacaaaata aagaatggaa gatggatttt
     9601 tctgtatcag aattgtatgg acaaagagtt ggatttttag gaacaggtac tatatcttca
     9661 gaagcagcaa aaagattaaa agcttttggt gtagaaatat ggggtgtcaa tactgatgga
     9721 agtagtaaaa aatactttga taagtgtttt gctactgagg atatgaatat tgtatttgaa
     9781 gaatgtgata tagtagttgt agcaatgcct tctacaaaaa gtacagatgg aatagtaaac
     9841 aaagatatgt ttaaacttat gaaagatggt tctgtattta taaatgtagg tagaggaaat
     9901 acagttaatc agaaagattt agaagaatgt gtagagaaat ttagaggggt agcattagac
     9961 gtatttgaaa gtgaaccttt aaacaaggac aataagttgt gggagtgcga aaatgtcata
    10021 gtaactcctc ataattcttg ggtgtcagat aaaaacaaag agagaacatt taatatggtt
    10081 tataataatt tgaaacacta tataatggag aataaacctg tagataatgt tgtagacata
    10141 tcaagaggct attaaaaata aaaaattttg ataaaaataa aaactcttat tagtcgtatt
    10201 aaagatacta ataagagttt tttttgtaat aaatttaaag ccaaaaaagt gatatactaa
    10261 aaaatatata aataggagat aattaattat agggaaattt caaaataatt taattttaaa
    10321 aatatgaaga ggtgcaaaaa gtgagcataa aagatgaaat taataaactt atagagacaa
    10381 taaactacca taatgaaagg tattataatc aagatagccc agaaatatca gattatgaat
    10441 acgataagtt aatgaaggag ttaatttctt tagaagaaga acatccagaa ctaaagagaa
    10501 ttgattctcc aacaaatagg gtaggaggta agccattaga taagttcaat caaattgtac
    10561 ataaaactcc tatgttgagt ttatcaaatg ctttttcaga gcaagatttg agagattttg
    10621 ataagagagt tcaagaatat gtgggagaaa atgttgaata tgttgttgaa tttaaaatag
    10681 atggtctttc tgtaggtcta acttataaca atggagagtt tgaaaaagga gcaactagag
    10741 gagatggagt tgtaggagaa gatatttctc aaaacttaat gacagtaaaa agcatacctc
    10801 ttaagataaa tgataaaaaa gaactaatag ttagaggaga agtatatata tcaaaagata
    10861 attttagaaa agtaaatgaa caacaagaag aacaagaaca gccattattt gctaatccaa
    10921 ggaatcttgc agctggttca ttgagacaat tagacccaaa actaacagca aagagaccat
    10981 tagatatatt tgtatttaat atggaaaata tagaagaata cgatttagaa agtcacagtg
    11041 aatcactaga gtacttagaa aaactaggat tttcagtaag tcagagttat aaagtttgta
    11101 aaagtataga tgaagttatt gagcatattg aatactggac agataacagg ggtaatttag
    11161 actacgaaat agatggtatg gtaataaaag taaacaatat aaaacaaaga gacgaaatgg
    11221 gatatacagc caaaagtcct agatgggcaa ttgcatataa attcccagca gaaaagaaga
    11281 aaactaaaat agtagatata atagtagaag ttgggagaac tggtacaata acaccttcag
    11341 caattcttga accagtcaga cttgcaggta ctactgtaag tagagctaca cttcacaatg
    11401 aagattatat aagagaaaaa gatataaaaa taaatgatac agtattagtt caaaaagcag
    11461 gggacataat acctcaagtt ttagaagtta taaaagaaga acgtactgga gatgaaatag
    11521 attttaaaat gccagaaaag tgtccagttt gttcagagcc aacaataaga ttagaaggag
    11581 aggctgctgt aaaatgtatc aatatgtctt gcccagccca aataagaagg ggaattatac
    11641 actttgtgtc aagggatgca atgaatatag atggattggg agaatctata attacactgc
    11701 tattaaatga aaaaattatt caagatgtat ctgatttata ttatataaaa aaggaagatg
    11761 tagtcgacct agagagaatg ggcgaaaaat ctgctgacaa tttaataaat tcaattgaaa
    11821 aatcaaaaga aaatgattta tggagactta taaatggatt aggtattaaa tttataggag
    11881 ttaaagcagc taagatactt gcatataact ttaaggattt agatgaagta atttctgcaa
    11941 ctagtgagca actagaagaa ttagaggaat ttggaagtat aatggcaaac agcgttgtcg
    12001 agttttttaa ggaagacaaa aatatgaacg ttataaacaa gttaaaaaat gtaggagtaa
    12061 atacaaaatc attggataat acaggtgaaa aagtagaaaa aatatttgaa gggatgaaaa
    12121 tcgtattgac tggtacactt cctacattaa aaagaaatga tgcaaaagat atgatagaaa
    12181 aaagaggtgg aaaagctaca tctagtgtta gtaaatcgac aacatttgtt ttggcaggtg
    12241 aagaagctgg ttctaaactt actaaagcaa gtgatttagg aattaaagtt atagatgaag
    12301 agagattttt agaattatta aagttatcat cgaaagatga agtaaaagct gtattagaga
    12361 gttaaaaagt cgcttaattt agtagaaaac tactataatt aatgatagaa tagttcagta
    12421 agctaataag attacgaaaa atgacaataa ttaatatttg acaaaattaa aaattataaa
    12481 aataaattta taaaaaataa aaaatatgag aaaggatata aaaaatgacc agaagttatg
    12541 atagaagtaa tgaacagata agacctgtaa agataactag agattataca aagtatgcag
    12601 aaggttctgt tcttatagaa atgggagaga caaaggttat atgcactgca tcagtggaag
    12661 aaaaagttcc tcctttttta agaaatagtg gtactggatg gataaatgct gaatattcta
    12721 tgctaccaag agcaacacaa caaagaaaga taagagatgc atctagggga aaaattgatg
    12781 gaagaacaca agaaatacag aggttaatag gaagagcaat aaggtctgtt gtagacttga
    12841 ataaattagg agaaagaact atttgggtag attgtgatgt gattcaggca gatggtggaa
    12901 ctagaactgc atctataaca ggggcatttg tagcagttgc agaagcaata tataaattat
    12961 ataaagcaaa gacaataaaa gagatgccaa taacaaattt tgtatctgca attagtgttg
    13021 gtattgtaaa tggaatacac atgctagatt tatgttatga agaagattct aaagcacagg
    13081 tagatatgaa tataataatg actgataagt gtgagtttgt agaagtacag gggacaggag
    13141 aagagaaacc tttttcgaga gcagatttaa atttattgtt agagttaggt gaaaaaggga
    13201 ataaagaatt aataaggctt caaagagaag ctttaggtga aatagcagat gagatattgg
    13261 gtatggatta tggtaatgaa gtagtgattg ctactaataa tgctcataag ctagaagaaa
    13321 taggtgaaat cttaaaagat tttgaatata aagtgtactc tttaaaagat gttgatttag
    13381 caggtataga gatagtagaa gatggaaaaa catttgagca taatgcgttg ataaaagcta
    13441 gaacaatagc aaaaaagact aaacttatag caatatcaga tgattctggc ttagaagtag
    13501 atgctttagg caaaaaacct ggtgtttatt cagctagata tgcaggagaa catgcaacag
    13561 atgaagaaaa tagaaaaaaa ctgttaaaag ctatgcaaaa tgtaccaatg agcaaaagaa
    13621 atgcaagatt cgtctctgca atagcagtag tttttcctga tggaaaagaa tttgtagtaa
    13681 gaggaatttg tgaaggaatg ataggatttg aagaaaaagg taaaaatggt tttggatatg
    13741 atagcttatt tatagtaaaa ggatatgata agacttttgg tgaaatacct agtgttataa
    13801 aaaattcaat cagtcataga gcaaacgcac taaaacttat gaaacaagag tttataaaaa
    13861 gggtagtgaa gtaatgaaaa taggcatagt aagcgacaca catatgatga ttaaaaatat
    13921 ggaaaaaaca ataccatatt tgaaagaatg tgacctaata attcatgcag gagataactt
    13981 tactgattca agatatattc atagcatgac taatgtaggt attattgcag ttaaaggtaa
    14041 ttgtgacttt gatgctgttg aggaagaagt tgtctttgaa gtggcaaata aaaccatatt
    14101 cttatgccat ggagataagt atggtgtaaa atatggaact aatatgttag aaaaaaaggc
    14161 aactgaagtt gatgctgata tagttatatt tggccatacc cataccccat ttagagaaat
    14221 taaagatggt gtactttaca taaatcctgg aagcacttca cttccaagag gagtatcgta
    14281 taaaagtttt gtcattatga atatagaaga agatgacata aaaattgaag aaatacgcat
    14341 ataaaggtgt atttatctaa aaaaatggca aaaaacgctc aaaaaattaa attttatcaa
    14401 ataagtacaa cgatattaat ggaacacttg taaataaaaa aacttatgtg atataattaa
    14461 gtggttgaat tataaataga atgaattata ataccgttat cgggtattac ataaatatca
    14521 ctaggaggat tagaaggatg aaagcagaac taattaaaaa agagggtaat aaagttactt
    14581 taaaaataac agtagataac aataaatttg aagcagcagt aaataaggct tataataaaa
    14641 gcagaaataa atacaatata cctggattta gaaaaggtaa agctccaaga attgttatag
    14701 agactcaata cggaaaaggt atattctaca atgatgctat agaaatatta ttcccagaag
    14761 tttatccaga agctatcaag gaattagaca tagacccaat agacaatcca gatttagata
    14821 tagaagaaat aagtaaagac aatgggttgg ttatggttct taatgtagaa gttaaaccag
    14881 agtttgaatt aggaaactac aagggtatag aaatagctaa ggttgagaat actgtaagtg
    14941 acgaaaatgt tgatgctaaa ctacaagaaa tggttgaaaa aaatgccaga ttagtaagtg
    15001 tagaagacaa agctttagaa gatggagata cagctataat agacttcgaa ggttttgaaa
    15061 atggtgtagc ttttgatggt ggtaaaggtg aaaattataa cttagttata ggttcaaaca
    15121 catttatacc aggatttgaa gaacaattag taggtaaaaa agctggtgaa gaagtagaag
    15181 ttaatgttac tttcccagaa gaatatcact cacaagattt agctggaaaa ccagttgtat
    15241 ttaatgtaaa aataaatgat gtaaaagtaa aagaattatc tgcacttgat gatgaatttg
    15301 ctaaagatac tagtgaattt gattctttag atgaattaaa agcagatgta agagctaatt
    15361 tagaagaaga agctaaaaat agagcagatg cagaaactag aaattcagta gtagaaaaag
    15421 ttgctgaaaa tacagaaata gaaataccag aagttatgat acaacatcaa atagataata
    15481 tgttaaatga acttaactac caattacaat atcaaggatt tggattacaa caattactag
    15541 agatgactgg tagaactatg gaagaattaa gagaagagag aaaagaagat gctaaaaaat
    15601 tagttaagtc ttctttagta ttagaagcaa taactaaagc tgaaggaatt gaagcaacag
    15661 aagaagaatt taaggctgag ttagaaaaaa tggcttctgc ttacaatatg gaagtagaaa
    15721 aaatagaagc ttctttaaga gatgctgaca aagaagatat aaaaggtcaa ataaaaataa
    15781 gaaaaacaat agatttatta gttgataatg caacaatagc ttaataaaat aaacgctaac
    15841 taatatagtt gacgttatga aatgtttagt atataatgat gtgcaaatat aatttagtta
    15901 aatgcgtata ataatttaca gtagcttaaa aaaagctact gtaaattata tagaataaag
    15961 ggggtataaa accatggcat tagtacctgt agttgttgaa caaacaggaa gaggagaaag
    16021 atcttatgat attttttcta gactattaaa agacagaata atcttcttag gagatcaagt
    16081 taacgatgcc acagcagggc ttatagtagc acagctatta tttttagaag ctgaagaccc
    16141 agacaaagat atacatttat atataaattc tccaggagga agtataactt ctggaatggc
    16201 tatatatgat actatgcaat acatcaaacc agatgtaagc actatatgta taggtatggc
    16261 tgcttctatg ggagcattct tgttggcagc aggagcaaaa ggaaaaagac tagcactacc
    16321 aaatagtgaa ataatgatac atcaaccatt aggtggagct caaggtcaag caacagatat
    16381 agaaattcat gcaaagagaa ttttaaaaat aaaagagact ctaaatgaga tattctctga
    16441 aagaactggt cagccattag aaaaaattaa aatggatact gaacgtgata acttcatgag
    16501 tgcactagaa gccaaagaat atggtttaat agatgaagta tttacaaaga gaccgtagat
    16561 agagagaggt gttaatatgt ctaaatatga agaaaaacga caattaaagt gttcattctg
    16621 cggtaaaaat caagatcaag taagaagatt aattgcaggt ccaaatgtat atatttgtga
    16681 cgagtgtgtt gaactttgtg acgaaattat tcaggaagaa atagaagata ctatagatga
    16741 agatactaca tctttaccaa aaccaaagga aatgatggag attctaaatg attatgtaat
    16801 aggtcaagaa aaagctaaaa aagctttatc agttgcggtt tataatcatt ataagagaat
    16861 atacagtaaa aaatctagta gtaaggatat agaaattcaa aagagtaata tacttttatt
    16921 aggacctaca ggttctggaa agacattact tgctcaaact ctagcaagaa ctctaaatgt
    16981 accttttgca atggcagatg ctacatcatt gactgaagct ggatatgttg gagaagacgt
    17041 tgaaaatata cttttaaaac ttattcaagc tgctgatttt gatatagaaa aagctgaaag
    17101 aggtataata tatatagatg agatagataa gattgcaaga aaatctgaaa acccatctat
    17161 aactagagat gttagtggtg aaggtgttca acaggcactt ctaaaaatat tagaaggtac
    17221 tgttgcaaat gttccaccac aaggaggaag aaaacatcct catcaagaat ttttaaagat
    17281 agatactact aatgtattat ttatattagg tggagctttt gatggattag agaagataat
    17341 tcaaaaacgt ggtggagata aaacactagg ttttggagct aaaatagaaa gtaaaaaaga
    17401 attagattta gggaagctat atgaaaaagt acttccagag gatttattaa aatatggtat
    17461 aataccagag tttataggaa gaataccagt tttagctact ttagagttgt tggatgaaga
    17521 tgcattaatg cagatattac aggaacctaa aaatgctcta gtaaaacagt ataaaaagtt
    17581 attggagtta gatgatgttg agctagaatt tgaagaaggt gctcttcgtg caatcgctaa
    17641 aaaggccata gaaagaaata caggagctag aggacttaga agtatagttg aaagcgtaat
    17701 gatggaaact atgtttgaag taccatctag agataatata aagaaggtta tagtaacaga
    17761 gaaatctgtg aacgaagact cagtaaatcc tatcatagta cttaaggatc aagaggaaag
    17821 tgcataagat gatgaaaagg agctttaaaa gctccttttt ttatgttaat atgctaaata
    17881 taaaataggt atcattatta taaaaatgtg agtaatatac ctagaatacc aaagacgaat
    17941 acaattgcaa tggaaccaat ttttccttta tataaaagat aaaatgatgc tataaatgca
    18001 attattccat ataaatccca attaacttct ttggcagatg aaaaagctgc tgataatatg
    18061 aatcctagag taattggtct aagaactgtc aataaatttt ctaccttttt attattttta
    18121 aatttagaaa ataactttga tataatagtt agacctatta atgcaaaaat tgtaacacca
    18181 atagttgcag ctagagaacc aaagaagcca gcagtcttaa atcctacaaa tgtagcacta
    18241 tttattgcta caggacctgg tgtagattgt gatatagcaa gtaaatccaa aaactcttga
    18301 ttagttataa agtgatattt agatataaat tcttgctgga taaatggtag catggcataa
    18361 ccgccaccaa aactaaatgc ccctatttta aggaatatta agaagagtag tattatttct
    18421 gacatagact atatacacct cctccaatta ttaaataaat agggcttata ttgaatacac
    18481 caacagataa aactgctata attaatagta gtatgttagt tttagacttt ggtagtttct
    18541 tgaacatgct cgtaaaagaa tacaatataa gagctattac aacaggcgca actcctttaa
    18601 aaaatccatc taaaatttta gatgatgaat ttttaaagta tagatacgat aagactaaga
    18661 ctatacaaaa tgatggtaaa gcagagccta aggtacatat aagaactcct ggtataccat
    18721 aaagtttata tcctaataat acagatatat taactgccag tactccagga taactttgag
    18781 ctatggataa ataatcaata aattcttcct gctctaaaag tttttgtttg tttacaagtt
    18841 catcttgtat aagaggaacc atagcgtatc caccaccaaa tgtaaacgca ccaattttta
    18901 aaaaggttaa aaacaatttc aacataatag aaacctccaa aagataaata acatctaagt
    18961 atactaatat taatattata tcataataaa aagataatat agtatgatag tattctaaga
    19021 atttatcatt aatgttgaaa attaacttgt tcaaatatat aatattaaaa gcaaagcaat
    19081 tagactagaa aaggagtaat gttgatggaa caaaattata ctaaaataga tcatgaatta
    19141 ccattaattc ctctaagagg attagctata tttccatata tgatattaaa ttttgatata
    19201 ggtagagaga tatctcttaa agctttagac caagctatga tggatgaaga acttatattt
    19261 ttaacttctc agaaagaagc agaggtagat gagccaggag aagaggattt ttatcatgtg
    19321 ggaacaatct gtaaagttaa gcaaatgata aaattaccag gagatacagt tcgtgttttg
    19381 gttgaaggtg tatcaagggg tagagtaaag aaaatagaac aagaagatgg gtatttcaga
    19441 gcagtaatag aagaaatagt atttgatagt gataatttgg atagtgaaac agaagttgaa
    19501 attgaagcat ttgtaagaaa tgtatttgat gcctttgaag agtatataaa tattggaaat
    19561 agggtatcac cagaaatatt aatatcttta gctgatatag aagatgtaga tagatttata
    19621 gatacgatag ctgcaaacat atatctaaaa tcaagccaaa aacaagaaat attagaagaa
    19681 tttgatatta gaaaaagact tgaacttatt tattctatat tattagagga aatagatata
    19741 ttaaaaatag aaaagaaaat aactttaaga gtaaaaaaac agatgaataa ggttcaaaaa
    19801 gaatattatc ttagagaaca attaaaagct atacagaaag aattaggtga agaagaagat
    19861 ataaactctg aagcagatga gtatagagaa aagcttaaaa aaataaaagc acctaagaca
    19921 actaaagaga aaatagaaaa agagatagat aaattttcaa aaatatcttc tatgtctcca
    19981 gatgtatctg taagtagaaa ctatttagat actatattct cattgccatg gaataaagag
    20041 acaaaagata aattagatat aactaaggca aaagatatat tagatgaaga ccattatgga
    20101 ttagaaaaag ttaaggagag aatactagag tatctagcta taagaactct tgctaagtca
    20161 cttaaaggtc ctataatatg tctagttggt cctccaggaa caggaaagac atctatagta
    20221 aaatcaatcg ccagagcatt aaatagaaaa tttgtaagaa tatctttggg tggagttaga
    20281 gatgaagcag aaataagagg tcatagaaga acttatgtag gttcaattcc aggaagaata
    20341 attaatgggg taaaagaagc ccaaacaaaa aatcctgtat tcttatttga tgagatagat
    20401 aagatggcag cagattataa aggtgaccca gcttcagcaa tgctagaagt attagaccca
    20461 gagcaaaata aggattttgt ggaccattac ttagaaatac cttttgattt atcaaaaata
    20521 ctatttgtta caacagcaaa tagtctaggt aatataccaa gaccattatt agatagaatg
    20581 gaagtaatag aagtatctgg gtatatagaa gaagaaaaat taaatatagc aaaaaaatac
    20641 ctacttccaa aacagattaa agaacatgct ttaaaagaaa gctttataaa aatagatgat
    20701 gaaactttaa gaagtataat caaccattat acaagagaag ctggagtaag aacactagaa
    20761 agaactattg gtaagatttg tagaaaggtt gcaaaaaaat acgttgaaga cccaactctt
    20821 gaagaggttg ttataaataa gtctgaccta gagacatatc ttggaaaaga catgtttaag
    20881 tatcaacttg cagaagttaa ccctcaaata ggattagtaa atggtcttgc atggacagaa
    20941 gttggtggag ttacacttga agtagaagta aacgtactta aaggtaaagg agaaattgta
    21001 ttaactggaa aattaggaga tgttatgaag gaatctgcga agacaggtat ctcttatata
    21061 aggtcaatag tggacaagtt tgatatagac cctgaatttt ataagacgaa tgatattcat
    21121 atacacattc cagaaggtgc tgttccaaaa gatggaccat cagctggtat aactatggct
    21181 cttgcagtaa tctcagcact tactaaaaga cctgtgcctg gaaatatagc aatgacagga
    21241 gagataactt taagaggtag agtcttagca gtaggaggag ttaaagaaaa gttattagca
    21301 gctcatagag ctggtataac aaaagtatta attcctaaag aatgtgaagc tgatttagat
    21361 gaaataccag aaaatgtaaa agaaaaaatg gagtttgtgc ttgtagaaca tatggatgaa
    21421 gtattagaac aagctttatt aaagagtggt gaaaataatg aaaattagaa gttcagagat
    21481 aactatgagt gctgtgaata aatcacagta tccagcagaa ggaatcccag agatagcatt
    21541 ggctggtagg tcaaatgttg gaaaatcatc aataataaat acattgctta acagaagaaa
    21601 ctttgctaga accagtcaaa caccaggaaa aactagaact ataaattttt atctaataaa
    21661 taatgaattt tattttgtag accttccagg ctatggatat gcaaagatag ctaagtctga
    21721 aaaagaaaag tggggaggta taatggaacg atatctagaa agtagacaag agttatgttc
    21781 tatattccta cttgtagata ttagacatga gcctacagca gatgataagc ttatgtatga
    21841 atggataaag cactttggat ataactgtgt agttattgca actaaggcag ataaaatatc
    21901 tagaggacaa tatcaaaaac acataagtat aataagaaaa aaattgcaaa tggaaagtag
    21961 tgaaaaagta attcctgttt cttcactaaa aaagactggt gttgaagaat tatgggaaga
    22021 gattgtaaat caatacaatc aacatggata tgaaataaca gtagattaaa tttaaaatgt
    22081 taaatattga cataagattt gtttgaataa taaatgtaat aatagttagt tttaattata
    22141 ttaatattaa agcaaaatat aggatgcctt aaaatagttt taatgaactt tttttggcat
    22201 ccttattgtt tataaacaat aaatatcagt aattttgcta aatactaata aattttagta
    22261 aggtatggga aaattagtat aaattagttc aactaaaaaa ttattgactt atgtagtcag
    22321 caataaatag catttaagaa atagatttat ctgtttttct cataaagaaa acagttagta
    22381 taagccctat aaaacatact gatgctgcaa tccaataaga ctgattgcta gctataacat
    22441 aggctgatgt gtgactttta aacttttgat tgtatgtaag actttgtgca aaaaaactac
    22501 taaaaaatgc tgttccaaga gcaaatgata aattacgaat agttgcaaga aaactgcctc
    22561 cgtatccctg tttttgagga ggaacatctg ctaaaatact actattgttt ggtgaactaa
    22621 atgctcctag cccaagtcca aaaataacta aacatacaat taaaagatac aatggagaat
    22681 ctgcttttaa aagtgccatt ccaactagtg agatggtcat aaatgaaaaa gatgctgtta
    22741 gaatgttttt tgcaccgtgt ttatcagaaa gtgaacctgc aataggtgct ataagtacca
    22801 taataagtgg atgtacagtc attacataac cagccatcat aggagataaa ttttttaatt
    22861 gttctaaata aaatggaagt agaaaagata ctgccatttg aggaaaataa caagctactc
    22921 caatgatatt gcctacagta aagtttctat ttttaaatag aggtaggtca ataaagcttt
    22981 gttcaaattt tacttctctt aatgccaaca ataagaagat tataagtgct gttataccta
    23041 aatacaatct tgtattaccc ttctcattca ttgcaagtaa tataagcgta gtgcaagatg
    23101 cgaaaagtag aagacctgga atatcaaagc tcttgttttg ttcatccaaa acaggtttag
    23161 gcagaaattt aatgccaaga aagactgcta taataccaat aggtatattg ataataaaaa
    23221 tagaaggcca tccaaaatgt tctaaaatta tacctccaat tacaggacca ctcatatttc
    23281 ctataccaac tacagctcca gtgattccta tagcttttcc tttttcattt gctggaaatg
    23341 cattggaaac tataccaagc ccagtagcca ttaaaatact tgctccaact gcctgaaaga
    23401 ttcttgaaga aattaatgtt gataaattgt ttgacatact acacagaaaa gaacctattg
    23461 taaatataaa aaatcctaat gtgtatagac gatttgaacc tactttatcg ccaagttttc
    23521 cgaaaaataa catagtagct gttacaacaa gcatataagc tgttacaacc cactgaattt
    23581 gtgacatgtt aattttaaag tcagcagcaa ttgtaggatt tgcgatattt agtatacttc
    23641 catcaagagt agacataaat acaccaatac agatgataat caatactatc catttttgtt
    23701 tcatgataac actccaatct taatagattt tataagtacg atataattgt aaaataaaca
    23761 acaaaaaaag cacctgtata ttaggtacct tgaatatgtc taatttcatg aataaatacg
    23821 gtagttgaag gatttgtata gattactcat gtaaaattac ataaaggtac tcatatacta
    23881 ttttcttcta ccatccagat tttactgtcg gctttggaat atgaccaaat tatgccataa
    23941 ggctcgcggg cttttactgc cgatagggaa tttcacccgt ttatgaagaa aaacagatgt
    24001 attttgtaat attattttaa cataaaatta taatggaaac aattggattt aagtaatatc
    24061 cagctgtatt acaatacaaa tatttcaata tggacactta aattgtattt atagatagaa
    24121 taaggaacag tatgagaatc tataataatt agataaaatt aacctgttat tagtattaga
    24181 tggcaagttt taaatttatc aaaatcagaa agctgtaata aaattcttat aatatgaata
    24241 tcttaattaa gagatattgt aaattatgag gaggcgctaa tatggaagga aaggtaaaga
    24301 aggcattccc gggtggaaat acatcacaag gctcatattc tttttttgac tatataattc
    24361 ctgaaaatgt aaaaagagtt ttttgtttaa agggtggacc tggagtagga aaatcctcac
    24421 ttatgaaaaa aatttataaa gagtttttgc atagaggata tgatattgat ttatatcatt
    24481 gtccttctga cccaagttcg ttggatggtt tagttataaa gaaattaggc gtggtactta
    24541 tggatgcaac tgccccacat actatggacc caaagctacc tggagctttg gatgagataa
    24601 ttaatttagg tgattactgg aatacagaag aattagaaaa gaataaacaa gaaatatcag
    24661 tttatgataa agatattagt aattcattta aaagagcatt taagttttta aaatcagcag
    24721 aaccaatctt tagagacata gaagaaaaat attctgattg tatggattat ggaaaagtaa
    24781 atttggtcac agaagaattt ataaaaaggt tatttgatgg agttaaaagc acaggaaatc
    24841 taaaaagaga aaagcattta tttggttcag ctataactcc tgtagggtgt ttagattata
    24901 cagaaaacat tttaaaagat gtaaagaaag tctattattt agatggagaa ataggaactg
    24961 ggaaaactac attattaaac aaagtatata agaaagctat tgaaaaaggt ttaaatgtag
    25021 aagtttatca ttatccactt attccagaga aaattgaaac tgtactatta actgatttag
    25081 atataggcat aactataagt acgactttta aagaagaaga tacaattgat ttaaatcagt
    25141 ttttaaatag agaaaaacta cttaaatatg aagaagatat taaatttgat gaaaaagttt
    25201 tagatgattt aatttgttgg gcagtactaa atcttaagag agccaagtct aaacatgata
    25261 ttatagaaag ttactatagt cctaatatga gatttgatga agtagggaaa ttaagagata
    25321 agttaattaa aagaatttta aaatatgagg aaaacttata aacgtatatg tttaaaatta
    25381 atgttaataa taatataatt tttagtaaat tggtgtagct ttgaggctat gccattttac
    25441 tttttttgct aaaaaatgat attaataatc tccaaagtca ttatttgttt ttcataatta
    25501 ttatttccgt tcctaattta tgttttttta taatatcaca acaatgttta ttgaaagttt
    25561 atataatttt aagaacatct aaaaatgcat acttgatatt ggtaaattag tgataggagt
    25621 tcaatgtatg atattatata ctaaagatga attttaatat ataactttga tataataagc
    25681 atatgtaaat gtttaatatt taattaaaga aaattatcat ataaaaataa atttgtaagg
    25741 agcaatacag tatgaaaaaa caatatgtgt ttataatact agcaagtact attttaggta
    25801 tacttgttgg aaccatattt agagattata acaatgaaga aacagtttat acaagcaaag
    25861 acaagtcaat aagaaaagaa ataaaaatga caagaaaatc tataaaagaa ttaaccaaag
    25921 agaaagacaa gttagataaa gaaattaatt caatgaaaca aaatcaaaaa aattctgaag
    25981 aaatatcaga aatagaaaca cttagagata gtctatcata ttcagatgta aagggtagtg
    26041 ggataatatt aagtatagat gctatagatg aaaaaacagg gaatatagct aatagtatag
    26101 actataataa gattcttgta aaagttataa atgaattaaa agtaaacgga ggaaaataca
    26161 tagaaataaa tggtcaaaga attaatcaat attcagaagt tgtacttgca ggaagccata
    26221 taaatataaa tggagttcct gtagcacaac catatgaaat aaagtgcatt ggagataagg
    26281 agaaactatc taattatgta gataaaggta gtaaatattt agatagcata caaaccaatt
    26341 atccaatgaa aataagcata aaaactgaag aaaatatctc tatgaaaaaa atgaatatac
    26401 ctaataaatt aaagtatata aagggtgatt aagattatat tagaggaaag cagtttgcca
    26461 atgttaatac cagaaaaact tgcaaaaaaa tataatgtat ttccagttga gtttcaagat
    26521 gataatttag ttgtagaaat agaagatgag gatatttatg ctctacagga cttgagatta
    26581 gctacaggta aagaaattat attgaagaag gagaaaaaag aacttataag tgaaaagatt
    26641 gaaaaatatt ataatagctt tgaacttgat gaggattatg caaaaaaatt atttgaaaat
    26701 cttttagaaa aagctataaa agaaaacgca agtgatatac atatagaacc atttaaagaa
    26761 catttaatag tgagaatgag ggtagatgga gaactaaagg aagtatcaaa atttttagtt
    26821 gatgtctatc catcattgtc tacggttata aaattaaagg catcaatgga tataacagaa
    26881 aaaaggcttc ctcaggatgg tagggtggat ataaagttag gtggaaattt aattgacatt
    26941 agagtttcat caataccaac tgtctatggt gaaaaaatag ttttgaggat acttaataga
    27001 gatacttttt taaaagacaa attagaactt ggtttttcag aggaagctat aaaatctata
    27061 aatcgtataa taaataaaag agcaggaata ttattagtga caggtcctac aggtagtgga
    27121 aagactacaa cagtatattc cttattaaat gatttaaaag gaataaataa aaatattatg
    27181 actatagaaa atcctgtaga gtataagatg gatggcataa gtcagattca agtaaattca
    27241 aaagtagggt tgagctttga tgtaggtctt agagcgatat taagacaaga cccagatata
    27301 ataatggtcg gagaaataag agatgcagaa acagctaaga tagcagtaag agcagctata
    27361 acaggtcatt tagttataag tactttacat actaatgatg cagtatcttc catagctaga
    27421 ttactagaaa tgcaaatacc accatatctt ttaaatgcct ctcttatagg tgttatatct
    27481 caaaagttgg ttagaaaagt ctgcaatcat tgtagccatg agattatgat aaaagataat
    27541 tttagtggag atgtaaatac taaggtagct gtagggtgtg aaaaatgtaa tgataaagga
    27601 tactttggaa gaacagcaat ttatgaaatc ttagaaatta atgatgatat aaagacatgt
    27661 ataagaaata tggaggattc tagtactatt aaagatgtgg cacaaaataa tggaatgata
    27721 acatttgaag atagttgtaa aagactaata aatgaaaaaa taacgacatt agaagagtgt
    27781 ttagtagtaa atgaaatgat ttaactgaat tgtatagtta aacttcgttt ggtcagttgt
    27841 ctttatttaa tctattttaa ttaagatgtt tgagtataaa ttatatttaa gtgaaataaa
    27901 attaaatgca ttaaattaga aaatattaag tttatttaat tgtaattaat ataatttgga
    27961 aggtattata gtacatgaga ttatctaaaa atatatttta taatttagaa aagttttatt
    28021 tagtattaaa tagaatcagt gataaagaaa ttagagtaat ttgcaaagag ataggcatat
    28081 tgctggaatc tggatgtgaa attacaaaaa tatttgaaat cattgagagt cagtcaagta
    28141 aaaaagtaaa gaatttgctt agtatagtat caaatcatat tcaaaaaggt aactcaatag
    28201 cagaatcatt tcaaataaca ggtatatttt ctaaattctt tataagtatg ataaaagcag
    28261 gagaaactag tggaaactta gatataataa tgagtgattt atctaattat tatgataaag
    28321 aatacaaatt aaaaatgaaa ataataacta tttcaatata tccaataata cttataatat
    28381 tatctatctt atcaatgttg tttatattcg tatttgtaat acctaatttt caggtggttt
    28441 ttaccaacaa tggaattgaa ccacctttaa taactagagt tttaatggga atatctatag
    28501 tggttacaaa taacttagct tatataatat ttagttttat attgttttca ataggaaaca
    28561 tttatttctt tataacaaat gataatataa aaaaattgat taattcgtta aaattcaaaa
    28621 taccttttat aaaaaaaatt aatcagttag tagctacaac aagattttca agggcattgt
    28681 ccgttttaat tagcagtgga atacaaattg tggaagctat agacatgtca gctagtgttg
    28741 tagacaacga atttatttat gaaaggttaa agatttccaa taattatata aaaaaaggaa
    28801 atagcatagg taaatctttg aatttagcaa atatttttcc aaaattattt atttcaatgg
    28861 caaatacagg agaagaaagt gggaaactag ataaaagtct aaatgtaata aataaatttt
    28921 atgaaaatga attaaataac aaaatagagc aaataatgaa atttatagaa cctatgctaa
    28981 ttgtatttat gggattaatt attggtactt ttattttagc aatggttgtt cctatgtttg
    29041 atgcaattac taatttttag agagaaaaat aaattttatt agatgaaact tttgaaaagg
    29101 agagaatatt taattgataa atttgataaa taaaaaacga aaaggattta cacttgttga
    29161 aatgattgta gtagtaacta ttttaggcgt tatatctagt atagcattag ttaagtatag
    29221 taaggttcaa gaaagtgcca aattaaatgc agactatacg aatgctgcta atatagtaac
    29281 cgcagctagc atggcaatta atgatgatga aaagacaata gactctctaa gtgtagagac
    29341 attgaaggaa aagggatacc taaatactgt tccagttcct cagagtacat caggtaaatt
    29401 cgaacttgtc ataaatgata gcggaacaga tataagcgta aatataaatt ctaagcaatt
    29461 ttatccaaaa taatatttta tattgattgc tgtaagtttt aaaattattt ttatttaaga
    29521 aggagatggc tataattaaa aaaattctaa acttagaaat aaatgatgat tatataaggc
    29581 ttgtattttt aagaaaaagt cataaaaaag tttttataga taaatcaatt ataaaagaga
    29641 ttaactttga tataaaaaat gatagtaatt cgattgagaa gattaaatat atagaagatg
    29701 tagttagatt tgtaaaagag gagattggta aatcaaaaat attatataaa aatttatact
    29761 ttaacattca aattcaggat atagtcatta gaaatgttga agttctaaat actaagaaaa
    29821 aaagagacat attaagcatg attgaatttg aaataacaca atacattcca ataaacataa
    29881 ataactattc aataaaatat aaagttataa attctaaaaa tgataaattg aatatacaag
    29941 taattctttt cccaaagagt attattcaat taattaagaa catttcagaa aatctaaata
    30001 tgaatccaaa gactataaat ataaattttg atatattaca aaagcttata aacttaaatt
    30061 taatagagaa tttttcagaa gaaggggtat ttatagaatg taaaaaaagt cagttaatta
    30121 taaatataac aaaagataaa aaaataagag aaacatactt gctatcaaaa gagggaaaat
    30181 catatgagtt cataaaaaga ttattaaggg attttaagta tgtttattac tatggtatag
    30241 aaaattgttt tattgaagaa tactttaaat atacagataa atctattgaa gtaaatccat
    30301 taagattaaa agataaagta aaagtagaaa ataattttga tgcagattta gaagacaata
    30361 ggataaatta tataaatagt ataggaatga ttatttaagt gaaagtggat aaaacaataa
    30421 attttcttaa tggatttaaa aaaactaaac catgtaataa aatctataaa ataataatag
    30481 tcttaatttt aacgtgtatt ttatttaaat catttatgta tgtgaaatct ataaatgaac
    30541 ttgaagatta tataagtcaa aataagctag tggataaatc aaagaacact ttaccaacaa
    30601 cagacaaaac tagagagaaa ttttctaaaa taaaacttaa tgaaataaaa aaaatatatg
    30661 aaacaattgg aataaatagt attactaaaa tatcaataga taaaaataag ctagagatgg
    30721 aaggtgtgtg tagtgattta gatgttttaa acaatttaag gaaaataaag tacataaaat
    30781 attattacat agacagtatt gtaagagatg gagaatatta tagatttaga ataaaaagtt
    30841 agatgggtga ttatttttga gattaaataa tagagaaaaa aatctactta aaatattgtt
    30901 aatattagtt attatattgg caagtgatat agcagtaagt tatttggaag aaaacctaac
    30961 tagtttgaag aatgaaaagc aaaatataat aaataaaata aataatcaag ataattatca
    31021 aataaaggat aataagcata tagatgataa atatatagaa agtgttgaat caaataaaaa
    31081 tgaagaatta aaaaataatt ttaataactc atttttagat aaaaaaacaa ataaagatat
    31141 agtgttatta gtagaaaatg aactgagaga tattgtgaat gtagaatata ttaatcaaga
    31201 aagtagttta gataatcaca ataaaaaaca agttaattta gaaataaaag ttaatggaga
    31261 acttgcaaat gtgttgaaac ttgaaggtgt aatgaagaag ttaagactaa ataataaact
    31321 tgaaaagata gaaattaata aattaaaagt caataatttt gatgttcaaa atattccaaa
    31381 tgaatataaa caagaaaaag acaatattgt tgaatgtaaa atgacagtta gagtcatata
    31441 acaaaaaaga atagataaag taaaaaacta ttatcaatta ataaaatttt atagaggaat
    31501 tagttttacg ataattcatt tctacaagag ggattgttga tgattttatc gaaatcctaa
    31561 ttaaagttaa tatattgtac caaaatataa gtgaatttaa tagaatattt acttatacta
    31621 tagattgatt aataaaaaaa tggtataata acaaattgta ctttaattta ataataaggg
    31681 agtggaagtc atattgttag ggagaaatga gctatgccct tgtggaagtg gcaaaaaata
    31741 caagaaatgt tgtttaaata aagatattgt ttcagaaaga gcatgcagaa aaactgaact
    31801 ttcacaaaaa caatatacag atttatattc aaagttatat gattattcaa gacaggataa
    31861 gtttaaagaa gaatgtgaaa aagctaaaga aatgttttat ataatgcaaa atgatagtgt
    31921 aaatgaaaaa tttgaaagat tttttaatac ttatttaata caagaccaca taatggaaaa
    31981 taaaaaggtt atgacagttg gttttcttga agaaaatggt gcaaacctaa gtcaatcaga
    32041 agtatcaata ttaaaaagta tgtttgaatc atacgtaagt atttatgagg taaaagaagt
    32101 ttctgctgga aaaatagtat taaaggactg tttaagtgga aatgaacttt gtacagaaga
    32161 tgtaaaactt ctgagaagtt ttaaaatcgg aagttgtatg atagctagaa tagttgatat
    32221 tgaaggaact aacatattga tagatataac tataagtata tcaaatgagg ttaaagatat
    32281 aattttaaag gatattatga atctattcaa tcaatatcaa gatgtataca aagatatgaa
    32341 gtcgttctta atttatcata cacatatact atacaagtat atacaacagc ttttagaccc
    32401 aagtatagct gaatatttaa agagagaaag agataaaaac gatacaaaag ttaattcaga
    32461 aaatgaatta gctgaagaag aatgtaaagt tctagatact cttaaagaaa atgtagaaaa
    32521 agaaaatata gatgcatgta tagagttttg gaatgaatat aagaaaaatc atgaaaatat
    32581 aaaaggagct gaaaatggtt gggcagctgc tgttgaatac tatgttaaaa aagaagcagg
    32641 acaacctata actcaagttc aaatatcaaa gaaatacgat ataagctcta gtacactagg
    32701 aaagagatac aaggatttaa aaatatctta attaattata aaaagcttta agtcatagat
    32761 aaagaatcta tagtataata tatgtataat gtttagaaag aggtattaat aatgagtctt
    32821 agtttaggaa atgcaattgc tgtatcaacg aactttataa aatctaaccc agctgtacct
    32881 gtgtacaacg gagaagaaat atatgcagtt atttatcata tagaaatagg atataataat
    32941 ggtgtatcac ctgataccaa acaatatata ataatagact ataaagagtt tgatttatct
    33001 atggataaaa aaaatgaact aataaatatt gctaaagagt actgtaaatc taaaggtatt
    33061 gtagaaaacg aaaaccttga aataaacctt ttagacaatg aagaagcaga gaacttctta
    33121 gaaaaggtgt ttaataatat gaaggttata agaggtctta taactaaaaa aggataaata
    33181 aatggactat ataggaatag aaaatataac accttatgaa aatacatatg aatttagtgt
    33241 atatgaatat gatgatgaaa tcaccttagg tagtgaaaag ttatatgtat gtgaattaag
    33301 ggttgtattg attaaagtta attctctgta tgttgaaaga ttgcataaat cagttgaagc
    33361 aatggtctta gtaaaaaact tgaaaaaaga tttagataaa acacttgttg taaacaaaat
    33421 aaagaatttt gtgctagatg agatttgggt agaaaatcta gtaaaagaga atatagaagt
    33481 tatatttgta gaaagctagg aataacccta gcttttttat attacaatct aagagaggaa
    33541 aacaatatgt taagagtatc taatgtaaaa cttggaattg ataaagatat atctttatta
    33601 aaagatgtta tacttaagaa gctaaaaata aaagaaaaaa acttagtcaa atatagtata
    33661 tataaagaat ctatagatgc tagaaaaaaa ggaaaaatgg aatttgttta ttctgtagat
    33721 gtagaagtta aagatgaaaa taaaatactt aactcaaaaa taaaagatgt aacaaaaata
    33781 aaggaaatca gatacgtaaa tgtacctgtg ggtgataaaa aattaaagaa taatcctttg
    33841 gtaattggta gtggaccagc tggcttgttt gcaggtctgc ttttagctca aatgggttat
    33901 gaaccaatca tacttgaaag aggtcttgat gtagacagta gaaccaaaga tataagtgat
    33961 ttttggacaa ctagaaaatt aaaaaataat tcaaacgttc aatttggaga aggtggagca
    34021 ggaacttttt cggatggtaa acttacaact agaataaaag atatacgatg tagaaaagta
    34081 ttagaagagt tagttcagtt tggagcacca gatgaaatat tatactcaca taagccacat
    34141 gttggaacag atatattaaa aaatgtagtt aaaaatataa gaaatgaaat aataagttta
    34201 ggtggtcaag ttagatttaa ttcaaaagta acagatatag ttgtatcaaa tgattctata
    34261 caatctgtaa taataaatga tactgaaaaa atagatacag atacaattat attagctgtt
    34321 ggacatagtg caagagatac ttatgaaatg ttgtattcaa gaggtataaa aatagttcaa
    34381 aaaccttttg caataggagc tagagttgaa catccacaag atttaataaa taaagcacag
    34441 tacaaggatt tttataatca tcctaggtta ggagctgcag attatagact tatagagcat
    34501 gtttcaaatg gaagaacagc atatactttt tgtatgtgtc caggaggtag tgtcatagca
    34561 tctgcatcaa atgattttga aatagttaca aatggtatga gtgaacatgc aagagataaa
    34621 ataaatgcaa atagtgcatt tttagtaaat gtaacgccag aagattttaa gagtgataat
    34681 ccactagcag gtgttcattt ccagcagaag tatgaaaaat tagcttttga attaggtgga
    34741 aaaaattata atgcaccagt tcagcttgtt ggagatttta taaataataa gacttctttg
    34801 aatttaggaa gtgttgagcc atcatataga ccaggatata cacttacaaa tttaagtgaa
    34861 tgtttgccta gcttcgtaac agagactatg agagaagcgt ttatatctct tgataaaaaa
    34921 ttgaatgggt ttgcaatgta tgatgctgtt ttgacgggag tagaaactag gtcatcatca
    34981 ccaataagaa tagtaagaga tgaaaatact ttagaatcag tgagtattaa gaatctatat
    35041 ccatgtggtg aaggtgctgg atatgcaggt ggtatagtta cagcagcagt tgatggtata
    35101 aaatgtgcag aaaaaataat acaaaaatac accaataata caaaaattta acataaactt
    35161 aatgattttt taatatttaa catgaattta acattatcac tcctataatt tgataaaata
    35221 caataggtta taaaattttt agatacagta atctctttac aaggaggaaa taatttgaac
    35281 attataataa gtctaatggg tggattaggt ctgttcttat atggtatgaa ccttatggga
    35341 gaaggtcttc aaaaatctgc tgggacaaag ctaaaaaaga taataaaact acttactagt
    35401 aacctattta tgggagtttt ggtaggtaca ggagttacag cagtaataca aagttcaagt
    35461 gctactactg taatggttgt tggtttcgta aatgcaggaa taatgacttt aaaacaggca
    35521 ataggagtta taatgggtgc taatataggg actactgtta cagcccaatt ggtatctttc
    35581 gacttaactg gtatggcccc agtagcatta ggtgtaggta ttatacttta tttatttgga
    35641 aataagccta gaataaaaaa tatagccgaa atacttatag gttttggtat attatttaca
    35701 ggtatggatt ttatgaagat ggcagtggag ccactaagag actatcaagg atttactgac
    35761 ttacttgtta catttggtag atatccacta cttggattat tattgggatt tgggattaca
    35821 gcaataatac aaagttcaag tgcatctatg ggtatgttgg ttgcactggc agcagaaggt
    35881 ctagtgccac tatcagcagc actgccaatt ctttatggcc aaaatattgg tacatgtgta
    35941 acttcactgt tatcaagtat tggtgctaac aaaaatgcac gaagagcagc tatgatgcat
    36001 ctaatcttca atgttttagg aacagtgata ttcttaatat tcttgaataa accagtagta
    36061 agcatggtta caagttggga cccaagcaat gttgcaagac aaatagctaa tacacataca
    36121 ttgtttaata taatatctgt attgatactt ttaccattta caaatcttat tataaaacta
    36181 gctataaagc ttgttcctga tagagcaggt gatatagatg aagatgaaac taaaactatt
    36241 aaatatatag atgatagaat gatagaaact ccttctatag ctcttgcaaa tacgataaaa
    36301 gaagcacttc gtatgggtga gaaggcgaag gaaagcctaa atgcatctat ggaagcttta
    36361 gtagaacatt caactgaaaa aatagataag acatataggc gagagagatt aatcaatgat
    36421 ttacagaaag ctattttaaa ttatttactt aaactttcaa aagcaccttt agatgatgat
    36481 tcaagagaag ttgtggatac tttgtttaat acagtcaatg atatagaaag aattggtgac
    36541 cacgctaaaa atatagctga attatcgcaa gttgcaatag attcaaatat ttctttctca
    36601 gaagaaggac aatctgaact tgatgttatg tataatagag ttgtttcagc atatacttat
    36661 gcattagaat caatgagaac tgataatgtt gatttagctt gtaaggttat aaaaattgaa
    36721 gaacaagttg atataatgga gaaatcttgt agagctaatc acatgtatag attgaacaat
    36781 aatctatgta gtatagaaaa tggagttatt tatttagacg taataagtaa tttagagaga
    36841 atatctgacc atgctgtcaa tatagcacaa caagttatag caaagagatt aggaaatgat
    36901 taaaaataat taatttaaaa taatataaaa tttaaaatag aggataaata aaagagaaac
    36961 tttaaatgat acgtttagag tttctttttt tgtaaattta tttgactaaa atttttaaat
    37021 ttatacatag ttatagcatt tagaagaatc gatttcctga taataaatga tgagatatgt
    37081 atgattttgt ggcaaacttt taaaaaaaac acctatattt tgtgttataa tctctttaaa
    37141 acgaatatgc tgaaaagagg gatttaaatg ggaaaaataa attttgatta tagtaaagct
    37201 acagagtttt tttgtcaaaa cgaaatagat gtcatgcaac catatgtaga tgttgcgcac
    37261 gacatgttac ataataaaac tggtttagga aatacttttt taggatggat agaccttcct
    37321 aaaaattatg ataaagaaga gtttgacaga ataaaaaaat ctgctgataa gataaaatca
    37381 gactcagatg ttcttttggt aataggtata ggaggctctt atttaggttc gagagctgct
    37441 atagatatgg taagtcattc ttttaggaat ggacttaaaa aagagcaaag aaaggctcca
    37501 gaagtatatt ttgtagggca taatataagc tcaacatata ttatggattt attagatata
    37561 attgaaggaa aggatatttc tgtaaatgta atatctaaat caggaactac tacagaacca
    37621 gctctggctt ttagaatatt taaagattac ttagagaaaa agtatggtaa ggaagaagca
    37681 agaaagagaa tttatgcaac aacagatgca agtaaaggtg cacttagaca gttagctaca
    37741 gaagaaggat atgagacttt tgtaatacca gatgatgtag gtggtcgttt ttctgtattg
    37801 acagcagttg ggttacttcc tattgctgct gctggacttg atattgatgc tatgatgaaa
    37861 ggcgcaaatg atgctagaga agcatttcaa aatcctgact taaaaagtaa tgatagttat
    37921 agatatgctg ttgctagaac aattttacat agaaaaggaa aagatgtaga gttattagtg
    37981 aactatgaac ctcaactaca ttatgtaagt gagtggtgga aacagcttta tggagaaagt
    38041 gaaggaaaag aaaataaagg tttattccct gcttctgtag atttctcaac agatttacat
    38101 tctatgggtc aatacataca agatggaaaa aggcttttat ttgagacagt acttaatgtt
    38161 gaaaactgta agagaaatat aactataagt tcagaggaag tagacttaga tggtttaaat
    38221 tatttagcag gcaagactgt agattttgta aatcataaag cttttgaagg aactctattg
    38281 gctcatacag atggaaaagt acctaattta gtaataaata tacctcaact agatgagtat
    38341 aattttggat atttagttta tttctttgag aaggcttgtg gaataagtgg atatttattg
    38401 ggagttaatc catttgacca accaggagta gaagcttaca agaaaaatat gtttgcttta
    38461 ctaggcaaac caggttatga aaaagaaaag gaagagctag aaaaaagact taaataattt
    38521 taaatagtta aggtttaatt aagattaaaa taatataatg aaatcatcga aaaggagttt
    38581 actcaaaata gatgatttca ttttttttat gaaaaattgg gaaaaatata ttttgataat
    38641 ttatattata ttaagatagg gagtggtatg agatgtcaag aagaaagaaa gggataagtt
    38701 tagtaatatt agttgctata ataagttcaa tacttagtag ttttctaaca ataattttag
    38761 ttaaggacaa tttagtaagt aaatctacag gaagttctac gccgatagtt gtaaatgatg
    38821 atggtaagag tcaaaatatt tatcaagcag ttgcagaaaa agctacgcca tctgttgtag
    38881 gtattacaac aactagtgtt gatactagta atatgtttgc aataccaact gaaacacaag
    38941 gtgtaggaac tggaatcata gttgattcaa atggatatat acttactaat tctcatgtta
    39001 tatcagatgg tcaagctaca agtgtaaatg tattattcaa tgatggttca acaacttcag
    39061 gtaaagtagt atggtttgac caacaacttg atttagctat agttaaggtt gataaaactg
    39121 gactaacacc agcagaattt gctgatagtg acaaagtaaa agttggagat atatcaatag
    39181 caataggtaa tcctcttgga ttagattttc aaaaaacagt tactcaaggg ataataagtg
    39241 gattagatag aactatacaa acagaaaaaa ctaatatgac tggtttatta caaactgatg
    39301 caagtataaa tgcaggaaat agtggaggac cattgttaaa tcaaaaaggt caagtaattg
    39361 gtataaacac agcaaaagct tctcaagcag aaggattagg atttgcaata ccaatcaata
    39421 cagctaagag tatagttgaa gaagtaatca aaaatggaaa atatgaaaaa gtaactttag
    39481 gcataaaagg tacagatgta tcaaattatg aagcagcaac aggtacaaaa ttaagtactg
    39541 ataaaggtgt ttatgttgca gaagtaatat ctggttcatc agcagaaaaa gctggagtaa
    39601 aggtagggga tattataact aaagtaggag atacagatat aacaggtatg aatgatttaa
    39661 ataaaaagtt gtatactttc tcaaaaggtg ctagtacaaa aataacagta aatagaggcg
    39721 gaaaagcagt aacaataaat gtgaatttct aaatatgacc agaaagatag agactacatg
    39781 gtaaagtgta gtctctattt ttatttaatt tttatagtat atacatctaa attaatt
//
LOCUS       DAEOTL010000031        39498 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEOTL010000031 DAEOTL010000000
VERSION     DAEOTL010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.031"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            447..3995
                     /locus_tag="KRH82_001914"
     CDS             447..3995
                     /locus_tag="KRH82_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8655193.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLKSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADMALY
                     SAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRWFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            4180..6114
                     /locus_tag="KRH82_001915"
     CDS             4180..6114
                     /locus_tag="KRH82_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBG8655194.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            6220..7215
                     /locus_tag="KRH82_001916"
     CDS             6220..7215
                     /locus_tag="KRH82_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655195.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            7187..7972
                     /locus_tag="KRH82_001917"
     CDS             7187..7972
                     /locus_tag="KRH82_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBG8655196.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7960..8658
                     /locus_tag="KRH82_001918"
     CDS             7960..8658
                     /locus_tag="KRH82_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655197.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8781..9254
                     /gene="ybaK"
                     /locus_tag="KRH82_001919"
     CDS             8781..9254
                     /gene="ybaK"
                     /locus_tag="KRH82_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBG8655198.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9451..10290
                     /locus_tag="KRH82_001920"
     CDS             9451..10290
                     /locus_tag="KRH82_001920"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBG8655199.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10303..10851
                     /locus_tag="KRH82_001921"
     CDS             10303..10851
                     /locus_tag="KRH82_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBG8655200.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10917..12098
                     /locus_tag="KRH82_001922"
     CDS             10917..12098
                     /locus_tag="KRH82_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBG8655201.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12393..12779
                     /locus_tag="KRH82_001923"
     CDS             12393..12779
                     /locus_tag="KRH82_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8655202.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYNMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12929..13192
                     /locus_tag="KRH82_001924"
     CDS             12929..13192
                     /locus_tag="KRH82_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBG8655203.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13321..14163)
                     /locus_tag="KRH82_001925"
     CDS             complement(13321..14163)
                     /locus_tag="KRH82_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBG8655204.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14458..15192
                     /locus_tag="KRH82_001926"
     CDS             14458..15192
                     /locus_tag="KRH82_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8655205.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            15202..16335
                     /gene="nagA"
                     /locus_tag="KRH82_001927"
     CDS             15202..16335
                     /gene="nagA"
                     /locus_tag="KRH82_001927"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBG8655206.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAKVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            16434..17183
                     /gene="nagB"
                     /locus_tag="KRH82_001928"
     CDS             16434..17183
                     /gene="nagB"
                     /locus_tag="KRH82_001928"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBG8655207.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17358..17630
                     /locus_tag="KRH82_001929"
     CDS             17358..17630
                     /locus_tag="KRH82_001929"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655208.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            18290..18994
                     /locus_tag="KRH82_001930"
     CDS             18290..18994
                     /locus_tag="KRH82_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655209.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18996..20483
                     /locus_tag="KRH82_001931"
     CDS             18996..20483
                     /locus_tag="KRH82_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655210.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDANTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20688..22301
                     /locus_tag="KRH82_001932"
     CDS             20688..22301
                     /locus_tag="KRH82_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8655211.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22664..23494)
                     /locus_tag="KRH82_001933"
     CDS             complement(22664..23494)
                     /locus_tag="KRH82_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8655212.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23566..25293
                     /locus_tag="KRH82_001934"
     CDS             23566..25293
                     /locus_tag="KRH82_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655213.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25330..27192
                     /locus_tag="KRH82_001935"
     CDS             25330..27192
                     /locus_tag="KRH82_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655214.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27525..28214
                     /locus_tag="KRH82_001936"
     CDS             27525..28214
                     /locus_tag="KRH82_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBG8655215.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTVSVIDDNMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28319..29005
                     /locus_tag="KRH82_001937"
     CDS             28319..29005
                     /locus_tag="KRH82_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBG8655216.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            29022..30929
                     /locus_tag="KRH82_001938"
     CDS             29022..30929
                     /locus_tag="KRH82_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBG8655217.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSVDLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31382..32071
                     /locus_tag="KRH82_001939"
     CDS             31382..32071
                     /locus_tag="KRH82_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655218.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32507..33046
                     /locus_tag="KRH82_001940"
     CDS             32507..33046
                     /locus_tag="KRH82_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655219.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            33065..34108
                     /locus_tag="KRH82_001941"
     CDS             33065..34108
                     /locus_tag="KRH82_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655220.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            34110..34946
                     /locus_tag="KRH82_001942"
     CDS             34110..34946
                     /locus_tag="KRH82_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655221.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            35051..35725
                     /locus_tag="KRH82_001943"
     CDS             35051..35725
                     /locus_tag="KRH82_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655222.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35725..36777
                     /locus_tag="KRH82_001944"
     CDS             35725..36777
                     /locus_tag="KRH82_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8655223.1"
                     /translation="MIKFKKAISLIAVGMMIVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            37007..37855
                     /locus_tag="KRH82_001945"
     CDS             37007..37855
                     /locus_tag="KRH82_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8655224.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37845..>39498
                     /locus_tag="KRH82_001946"
     CDS             37845..>39498
                     /locus_tag="KRH82_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8655225.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKSDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKK"
BASE COUNT        15642 a         4041 c         6880 g        12935 t
ORIGIN      
        1 ttattatctg gtaacttaag ttttgagtat taatctaaag tatatgtttt tatatggttt
       61 aaattttatg tatacaaaat taatttgcta actgaatcat ataaaaaaaa acaaaatatt
      121 ttttagaggg aatgattaga tagaattttt ttgttatgaa attaattgaa gagtaattaa
      181 ttagaaaagg aatgaataat aatgaatata ttacattatt actttttgat aaatcaaaaa
      241 taaagttata atttttaata ttaattaaga atgatgaaat atgaataaag attttacaaa
      301 taaatcttaa gctatcttat ttaattctaa tacaggaaga aggtaaatgt atattgaaaa
      361 aatcatagaa atagaagtaa acaatttaaa taaatacaaa ggtttgcaaa agaagtaata
      421 taattatata caatgaggat gtgagtatga tgaacagact aaagccaaga attttaggta
      481 ttagtatctt gtttattatt ataattattt taacatgtgg agctgttttc aagtttaaat
      541 ttaaattaga taataaatta aaagaaacca cacatacata tttgtctgag tttacagaac
      601 acaatataat taatctcaag acaagactta gtggtcaatt tgacatgctt gaatctattg
      661 ctaacttcat aggaaacttg aataatataa atgatgaaat ggtgattgat ttaatggatt
      721 ctgatgtaaa gcgaagttct ttaattagaa tgactatctc tacattagat ggggaatgtt
      781 attctaatga tggaattacc cataatgttc aagatagaga ttattttaaa aaagctaaaa
      841 atggagaaaa gaatatatca gagcctttaa aatctattgt taataataaa gaaataatag
      901 ttttatctac cccagtttat aaaagtggga aaatagttgg tgttttaagt ggaatttatg
      961 attcaaaaaa gttaaatgag ttattaggat tatctgcatt tgatgaaaaa gcagatgttt
     1021 ttgttgcaaa gaaaaatgga gatatagttg ctcaaaaaac aaataaaaat agaaagacgc
     1081 tatcatgtat atttcagctt tttgacaaag ataactgtga tgaagatgat tgtctaaaaa
     1141 ctataaaaga aaatatgaaa aatgataagt ctggatattt taattataac ttagataatg
     1201 aaaaatttat gttaaactat cagccacttg gagttaatga ttggtatgtt ttttctgttg
     1261 tgccaaataa aatagtatct attcagtcag agaatatatc ttatgatgta tatatttttg
     1321 cattagaaat actactagtt atattgattt ttataatata tatagcatgt attataaata
     1381 ataacaccaa aattattata aatgaaaaag aaaaatttaa agtactcact gataatatat
     1441 taggaggggt taaaacctgt ttaaaagatg aatatatgac tatgacatat gtaagtcagg
     1501 ggtttttaga gcttacaggt tactcttgtg aagatttaaa taaaatattt aaaaatagat
     1561 ttaaagacat gatttataaa gatgatttag acaagtttaa ttgtattatt ctaaatcaat
     1621 tagaaaaaca agataaaatt gaagttgaat atagaattgt aagaaaagat ggaagtataa
     1681 tttggatttt ggagagaagt aagtctataa atgataataa aggaagtgag tgtattcagg
     1741 gagttttaac tgatataaca gaacttaaga aaatacaaga agaattagat tcaaaaagat
     1801 ttgaaataca ggctatcaat gatagtattg ttggtggaat agtgataact gagataaatg
     1861 atgattttga tagtatatat ttaaatgaag gttatttaaa tatgattgga tatacacgca
     1921 aacaactgga agatgagcta aataataaat taatcaaact tatttttaaa gatgatagaa
     1981 cagaattaat taatagtata aacaaacaac tcaaattaag tgatacattt gcatctgaac
     2041 aaagagttga aaaaagggat ggcactatta tatggatttt attaaaagga agaaagatga
     2101 tttatgataa tggaaaatct gtactttgtt gtgttattgt agatattact tctgctaaat
     2161 tattagagca agaacttaaa aagagtgaag aacgtcatga aatcatttta aagcagacgc
     2221 aaaatattat aatagaatgg gatatagaaa aagataaaat gaatatatca cctaattggt
     2281 ataataagtt taaatatgac cctataactg aaaacgcaac aaaaaatata attaaatcag
     2341 tagatatata tcatgatgat atggataagt ttatttcatt aattaaactt acttcacaag
     2401 gtagtgagta tgaagagtgt gaaattagac ttagaactag agatactatt tacgcttggt
     2461 ttagtataaa ggcaacaact ttatttgata ataatggtaa accttataaa gtagtaggaa
     2521 gtttgactga tattgatgaa tcaaaacgag aagctgaaaa gttgaaagaa agggcagaaa
     2581 aagaccctct tacagatttg tataataaaa aagcatcaca atcacttata gaagagtaca
     2641 taacattgga taaaaaaaga aaaggtgctt taatgattat tgatattgat gactttaaag
     2701 gaataaatga taatttagga catttatatg gggatgctgt attaagtgaa attgcaaatg
     2761 acctaataaa tctatttaga gcaaccgata tagtaggaag aattggtgga gatgagttta
     2821 ttgtatttat aaaagatatt tctgaaacaa gagatattat aaataaagca gaagaattgg
     2881 taaaaacatt tgaaaggtct tttttaggta aaggacgaaa ttataaaata tcattaagtg
     2941 taggaattgc taagtttcca caagatggta tggactatat gacactattt agaaatgcgg
     3001 atatggctct ttactcagcc aaagggaagg gtaagaattg ttatacattg tatgataaaa
     3061 aaattgataa agtccaatat ataactaata caagaaatgc aggagatagt gataatgtag
     3121 agatgtcttt taaagaacat atcacaaatt atatatttga tatactatat gaatcaagtg
     3181 atatagaagt ggcagtaaat ttaattctaa gtatcgtagg taaacacttt aatgtgagtc
     3241 gcatgtatat atttgaaaat tcagatgata atcgagtatg taaaaataca tttgaatggt
     3301 gtaacgaagg tgtaacctcg gaaattaata atcttaaaaa tatttgttac aaggatttag
     3361 gcaactatct tttaaatttt aatgcagatg ggttatttta ttgtaatgat attgaaaatt
     3421 taggtagtga tgtgaaaaaa gtacttaagc cacaaggcat acgttcaata ttacaatgta
     3481 aaattttaga gggtaatgaa tttagatggt tcataggatt tgatgaatgt tcatataatc
     3541 gtatgtggac taatgatgaa gtgaacactt tgacatttat atctaaaacg ctcagtatgt
     3601 ttttattaaa aatgcgtatt cagagtaagc tagaagagtc tttaacaatt caaaaatctg
     3661 tgatggataa tatggatata tgggcatatg ttgttgacag gaatacctat gaattactat
     3721 ttatcaataa aaaaatgctt gagtcagcac caaacactca tgtaggtgat ttatgttata
     3781 aagcgatatg gaataatcaa gataaacctt gtaaaaaatg ccctatgata tatttaaaag
     3841 atggtgatga tacttataaa tcattcatgc ataataaaaa gtttgaggta caggcaaata
     3901 taactacaac tactttgaaa tggtttgatg gtaaagatgc atgtttaata tttggaagtg
     3961 aaataactag tattgaagct gaagaaaata cttaaaatac tgtgttatat atatacttaa
     4021 aatcgcaatt tgaatttatt agacttaaaa tgtctatata aatcatttaa gttgtggttt
     4081 taagtatttt ttatgatata attaagcgtt aagaacaaaa ttaaaagata cttttgtata
     4141 aaaaaatatt tgttaaatat atattgagca ggtgataata tggaaaataa gtttttacca
     4201 ataagcaaac aagatatgat agatagagga tgggaagaat tagattttgt tctagttaca
     4261 ggagatgctt atgtggacca tcatagtttt ggaacagcaa taatatctag agttttagaa
     4321 agtgctgggt ataaagttgg aataatagct caaccagact ggagaactac agatgatttt
     4381 atgaagctag gaaaacctag acttgcattt ctagttaatg caggaaatat ggattcaatg
     4441 gtcaatcatt attctgtaag taaaaagcat agagaaaagg atatgtattc tccaggtggg
     4501 aaaatgggtt atagaccaga tagagctact atagtatatt gcaataaaat aagagaagca
     4561 tacagtgatg ttgcaatagt aataggtgga attgaagcga gcttaagaag atttgcacac
     4621 tatgattatt ggagtgataa ggttagaaag tctatgttaa tagatagtgg agcagattta
     4681 ttagtttatg gtatgagtga aaagcagatt gtagaagtag ccaatgcact taatgatgga
     4741 tatgacccaa aatacattag acatattgat gggacatgct atatttcaga tacattggaa
     4801 gaaatatatg ataaatatat attaattcca tcatataaag aaatttgtga agataaaatg
     4861 aagtatgtag aagcttttaa aattcaatat gatgagcaag acccatttag aggtaatata
     4921 attgttcaac ctcatggaag taagtatctg gttcaaaata agccagaaaa accacttagt
     4981 agagaagaac tagatgaagt atatggatta ccatatcaga agacatacca tcctgtgtat
     5041 gaaaaatttg gaggaatacc agctatagaa gaagtaaaat ttagtatagt aagttcaaga
     5101 ggctgttttg gtagttgttc attttgtgca ataacatttc atcaaggtag agcagtgcaa
     5161 agtagaagtg aaaaatcaat tattgatgaa gcaataggaa taacaaattt agatgatttt
     5221 aaagggtata tacatgatgt tggaggtcca acagctaatt ttagaagacc agcatgtaaa
     5281 aaacaaatta ctaaaggtgc ttgtaaaaat agacaatgct tatctccatc accatgtaaa
     5341 aatttagatg cagaccacag tgaatactta catttactta gagctgtaag aaaattacct
     5401 aaaataaaaa aggtgtttgt gcgttctgga attagatacg attatgtaat ggcagataag
     5461 aacaataaat ttcttagaga gttgatagag catcatgtaa gtggtcagtt aaaggtagcc
     5521 ccagaacata tatcagaaga agttttaaag tatatgcaaa aaccagcagg aaaaacttat
     5581 gataaattta gacagaagtt ttttgctata aatgaagaat taggtaaaaa gcaatatttg
     5641 ataccctatt taatgtctag tcaccctggt tctaccttaa atagcgctat agagttagca
     5701 gagtatttaa gagatactca ctaccaacca gagcaggttc aggattttta tccaactcca
     5761 gggactctat ctacaaccat gttttataca ggtattgacc cgcttacaat gaagccagtt
     5821 tatgttccta aatcaaaacg tgacaaggcg atgcaaaggg ctttattaca atatagagca
     5881 cctagaaatt atgatttggt atactctgcg ttagttgaag caggaagaga agacttaatt
     5941 ggttttggac atagatgtct tataaagcca aaaaatgaaa agccttattt taatagaaat
     6001 aattctaaaa aaaatgtatc taaaggaaca aataaaaaca aaaaaactaa tacaaataac
     6061 agaagtaata aaaatcaaca aaaaagttca actaaaaaaa agaaaaaaca ttaaagtata
     6121 aataaaaata cttaaaaaag aaggattatt cgataaatta acagaaatta gtataaataa
     6181 atataattat tttaatgacg ttacctttgg gaggaagaga tgaaaaagta tatttctata
     6241 atattattag tggtgttgac tatggttgtt ttggtaggat gttcaccagg aaaagataac
     6301 cctaaaaata aggagctatc agttgtcaaa caagtaaaag tagctgttcc agatggacta
     6361 ccagcagtgg caatagctaa acttgcaaat gaaaatccag agattaaaga aggatatgaa
     6421 acagtgtata gcattgaaaa gacacctgaa gcgatttcca ctagagtgat gaaaaaagat
     6481 gcagatatag ctatagttcc ttcaaacatg gctgcaatag cgtataataa aacttcatca
     6541 tataatattg ttggaactgt aggaatgggt tcactttatt tggtgtcaac agaaaatata
     6601 aaagattatt ctgatttagt tggtaaagaa gttggatgta ctggaaaagg acttactcca
     6661 gacataacta taaaaagtct tttgttacaa aaggatataa attattcaga tataaaattt
     6721 aattatgtaa attcagcaag tgaactggta ccattattgg ctactggtaa agttaaaaca
     6781 ggtattgttc cagaacctgc acttagtgct ttgatgtcta aaaatccaga cataaaaatt
     6841 ataaaaagtt taaatgactc atggaaggaa gtaagtggtt caaaagatgg ttatcctcaa
     6901 tctactttaa ttgtaaagtc tgaattttta agagataata aagattttgt tgattctttt
     6961 gtaggtcaat tatcaaatag tatagattgg gcaaacaaaa atcctgaaga attaggtgca
     7021 tattctgaaa aaataaaaat atctactgaa tcaaagataa taggaaaatc tcttgaaaga
     7081 gctaatttaa aatatattcc agttaaggac atgattaaag attataaaaa ttactatgag
     7141 aaattagcta attttgatga taagacatta ggaggcaaag taccagatga agcaatatac
     7201 tttgttgaga aataaaaaaa ataaagaaca atttatagat aaaatggagg taacactttc
     7261 ttgtgttatc ctcttatttt tatggcaaat tattgcttta aaaattgata atgatatttt
     7321 tttaccaaca gtaggtcaag tatttaatag tataaaagag attatgctaa attctagttt
     7381 ctatatagat atactttact ctatggggag atgttttttt agttttttac tggctatgat
     7441 ttttgctatt atactttcaa tagtgtctta tttaaataga ttttttagaa acttattaaa
     7501 gccaatcaat gctttgacac gttcaatacc aactatgata ttggtagtac ttgcacttat
     7561 ttggtttgaa aaggatagta ccccttttat agttggattt actatagttt ttcctatatt
     7621 gtatgataac gttttgggcg ctatattgaa tatagacaag aacttattag aaatggctaa
     7681 tgtgtataaa ataaggttta tagataaggt gttaaaaatt tatttaccag ccataaaatt
     7741 tcaaattata tctatactag tatcaacatt ctctttaagt ttgaaagttg ctatagcagg
     7801 agaggtatat agtcaaccta catatggtat tggaactatg atacagactg aaaaaattaa
     7861 ctttaacaca tctggaatat ttgcatggat aattattgtt cttttaatat ctgctatttt
     7921 acaaatagct caaaagtttt tagcaaggag agctttttta tggaaaagat aaagttgagt
     7981 attgaaaata taaataaaag atatgatagt cgtattatat ttagagattt taatattgat
     8041 ttttatgtaa atgaggtaaa ttgtatcctt ggaaaatctg gttgtggaaa aactacactc
     8101 ttgaacataa taagtgggat tattaaaaat gacaccaaca atctaaatat caaagaaaat
     8161 ttaaatagag taggaaataa gcttgaagct agttacatat ttcaagatga tagacttata
     8221 gactggttaa cagtagaaga aaatataaag atagttgtaa ataaatacta taataaaact
     8281 caattaaata aaatttgtga tgaatacttg gaattggttg gaattagtga ttataaaaaa
     8341 ttctatcctc agatgcttag tggaggtatt agacaaagag taaatattgc tagagctttt
     8401 atatatccat caaaaaatat tataatggat gaacctttta aatctattga tgcaaagaat
     8461 acacagctta taatggataa tttcagaaat atattaagaa aagaaaaaag aactgtgtta
     8521 tttgtaactc ataatattga ggaagcattg tttttagcag ataggatatt tattttagga
     8581 gactctccaa ttagaataaa aaaaatatta aaaaattcta aggaattgga aaaaaatgaa
     8641 gttttgaagt tgatatagag ttataataat actgtcgttt taaaatatat ttggttaaaa
     8701 tctataagac tatattaaaa tagtacagaa tattcaaaac tgtgtataat gttcgtattt
     8761 tataaaaagg aagtgaatgt atggttaaga ctaatgctat gagaatatta gattcaaata
     8821 agattgatta taaagtaatg tcttatgaag tgaaaagtga acatgtggat ggtgttgagg
     8881 tggcacatga tataggaaga gatgtaaatg aagtgtataa gacattagta actcaaggag
     8941 ttagtaagaa tatatatgta tatgtaatac cagtacatga aaacttagac ttaaaaaagg
     9001 ctgcaaaagt agctaaagag aaaagtgtag agatgattca tgtaaaagat ataaataagc
     9061 ttacaggtta tattagaggc ggatgttctc ctataggtat gaaaaagctt tataaaactt
     9121 ttgtaaatga aagtgcaaag aatttagata caattattgt gagtgcagga aaaataggat
     9181 atcaaataga actatctcca tttgatttac aaagacttat aaaagtagaa tttgtagatg
     9241 taataaaaaa ataagaatta catataaaat atagagctta tattcttaat aataggtgtt
     9301 gtagtattaa taaaatgaat aataatttta aaataaatat tcagttactt atgtgtaatt
     9361 ggtataaaaa tattgagaaa ttttaaaaac aatggtaaag tgtaagtata atcacgaata
     9421 ttttttataa agtaatggag ggatgttcgc ttgagaaaaa taaaatctga acaaatcgtc
     9481 gagcaggtaa aaaaactttg tatagaagcg agcctatatt taggagaaga tgttttaagc
     9541 tgtataaaag aaaaagcgaa aagtgaaaag agtgaagttg gaaaaaatat attgaatata
     9601 ttagttgaaa atgctgaaat agctaaagaa aaaaatatac caatatgcca agatactggt
     9661 atggctgtat tttttgttga aataggacaa gaagttttaa ttgaaggaga cacacttact
     9721 gatgctataa atgagggagt aagacaaggg tatgaagaag gctacttaag aaaatctgtt
     9781 gtaagtccaa ttaacagagt aaatacaaaa gataatacac ctgctgttat tcattatgat
     9841 atggtaaaag gtgataaaat taaaatagaa tttgcagcta agggatttgg aagcgaaaat
     9901 atgagtaaga tgaaaatgtt aaagccatca gatggattgg aaggaattaa aaaattcata
     9961 atagatacag tttcagaagc tggacctaac ccatgccctc ctatggtaat tggagttggt
    10021 ataggtggga ctgtggacaa atgtgctcaa atagctaaaa aggcactttt tagagaacta
    10081 ggtgaattta ataaggacga aaatatagca aaacttgaaa gtgaactatt aacagctatt
    10141 aataaacttg gtataggacc tcaaggctta ggtggtacta caacagcttt gggattaaac
    10201 atagagactt ttcctacaca catagcaggt ttacctgttg ttgtaaatat aaactgccat
    10261 gcatcaagac ataagaaggt agtaatttag gaggaaaata aaatgataaa aataactaca
    10321 cctgtaaatg aaattgatat agcaaaatta aattgtggag atacaattag tttgagtggt
    10381 atactttata cagcaagaga tgctgctcat aaaagattga tagattgtat aaataaaggt
    10441 gaagaattac catttgacgt atatggtcaa ggaatatatt atgtaggacc tactcctaca
    10501 aagccaggag aagttatagg tgctgcaggt ccaacgacga gttatagaat ggatgatttg
    10561 actatacctc ttttagaaag aggtcttaga ttgatgatag gcaagggaaa aagaagtgat
    10621 gaggttatag aaggtatgca aaaatacgga gcagtttatc ttgctgcaat aggaggagct
    10681 ggagcatata tttcaaattc aataaaatca tgtgaaatta ttgcatatga agatttagga
    10741 gctgaagcta taagaaagat tgtagtagaa gaccttaagc ttacagtagc aatagatagc
    10801 tatggaaata atatatatga gcaaggtcga gcaatttatg aatgtaaata atgtttagaa
    10861 ataaatatga atatcaaaat taaaaatagt tgtgtatatt ttaaggagga aaattgatgt
    10921 ctaaggatta tgcaaaattg gcattagaaa tgcatgaaat caacaaaggg aaagtaagtg
    10981 tagaaagcaa ggtagaagtt aaaactaagg atgatttatc aacagcatat acaccagggg
    11041 ttgctgaacc ttgtttaaaa atacatgaaa atcaagatga tgtttataga tacacttcta
    11101 aagggaatct agtagcagta gttagtgatg gaagtgctgt acttggatta ggtaacattg
    11161 gtgctgaagc atctatacct gttatggaag gtaaagctat attatttaaa caatttgcag
    11221 atgtagacgc ttttccaata tgtttaaaga ctaatgatgt agatgagata gttaaatctg
    11281 tagagttgat ggagcctgta tttggaggta taaatttgga agacatatct tctccaagat
    11341 gttttgagat agaagagaga ttaaaaaaat ctttaagtat acctgttttt catgatgacc
    11401 aacatgggac agcaataata gttgcagcag ccataataaa ctcaataaag ttaattgaaa
    11461 ataaaaaaat agaagattta gaaatagtta taaacggagc aggagctgct ggtatagcca
    11521 tagcaaagat actacttaat atgaatgtta aaaatataat tttatgtgat agaagtggag
    11581 cattggaagc tagtatagaa aatctaaact atgttcaaaa agaaatgtta aaagtaacaa
    11641 atataagaaa tgaaaaagga cctttaaaag atattataaa aggaaaagat gtatttattg
    11701 gtgtttcagg tccaggagct gttacaaagg aaatggttga aagtatgtct gagaagccaa
    11761 taatattggc aatggcaaat cctactccag agataatgcc agaagaagca aaattaggtg
    11821 gagcatttat aatgggaaca ggtcgttcag acttccctaa tcaagtcaat aatgtactgg
    11881 cttttcctgg aatatttaga ggtgcacttg atgttaaggc taaagagata aatgaagaaa
    11941 tgaagatagc tgctgcatat gcaattgcta atacaataag tgatgaagaa atatgcccag
    12001 agtatatatt accagatgta tttaataaga atgtagtaaa aaatgttgct aaggcagtta
    12061 aagaagcagc gataaaaacc aaagtaaata gaatataaat ttttatatgt tcatatatcc
    12121 ttatcttatc gggtatatgg gcatttttat tataggttta tactcatata tccttacttt
    12181 tatatacata tctttatgat taaaggtgtt agaaaatgta gtaaatttta tactatcaga
    12241 ctctatcttt attactttag tagatacatg gtggtaaagg tttatagaaa aaaatatagg
    12301 aaggcagatt tttattgttg cgtatatatg agaatgatat aatatgaata ttataaatta
    12361 ataaatttaa atttatggag gtacaagaga tgatggaata taaagttaat gaccaagaac
    12421 ttaatgcttc aatgtttatc ccattcgtca acaggatatg gccaggagat tataatatgg
    12481 ataaaacaca gactgcatta tcaaaaactt tgaatataac tgcttatgat gataaagtgc
    12541 ttgtaggatg tctgcgagtt ctttcagatg gttattattt tggaacaatt acagaattgc
    12601 ttgttcttcc agagtatcag aaacaaggca ttggtagtaa gcttttccag cttgctaaag
    12661 agaacacccc aactatgcta tattttggtg cacagccagg agtagaagag ttctatgaaa
    12721 aaaatgggtg ccaaagaagt ctgcaatcct acataataaa aaagaaagat agttattaaa
    12781 gttccagctt tcaataatct taaaagtaca atattttagt ggaatcattt cattttttat
    12841 tactaatatg acataaacat gtcatattag cattgatata cttttaatat ggttaagagc
    12901 caaagaaaaa tataaggagt gatttaaaat ggaagaaact aaattttgcc aatgctgtgc
    12961 aatgccaatg ggacaaactg atgaattata tgggacaaat aaagatggaa gtaaaagtac
    13021 tgattattgt agttattgtt ttaaagatgg tgagtttaca gctgatataa gtatggaaga
    13081 gatgatagaa gtttgtatcc ctcatatgct tcaaagtaat aaggatatga ctgaagatga
    13141 agcaagaaca atgatgaaca atttctttcc aacattaaaa cgctggaaat aattttatgc
    13201 aaaattagtt atatgcaaaa catgaaatat ggtgttgaga ataaggggtg gtgtgcttta
    13261 tagcatacca cctgttttgt tacttggagt tcagttattt tcctaaatat tttaaatata
    13321 ctattttaga taagttcctt cttcatcttg ataaattaat ccttttttca taagcactcc
    13381 aagagctcgt ttaaaatttt tcttacttga attaaataat atagaaatat ctttagggtc
    13441 agatttatca ttaaatctca tatatccatc agaaccttct aaataactta aaatcttatt
    13501 ttctaaagta tcaagttcat cctttctatt tcctctagga gaaagaccaa gttttccatc
    13561 ttcatatatt tttatgacat gtaaattttc aagaacatca ccagttttta gttcagtaaa
    13621 gtactcatta tgaagtatta caccagcata tttattgtct acacatatca ttgcagaatt
    13681 attagtttgg aatccatata caactccagt tacaatatct cctacattgt aagtatggtc
    13741 tgttaataag tatgaatcta tatctgtagt agcagcaatt cttttgcttt tgtctaaata
    13801 tatataaaat aaatattttt cgtctctaaa tagtggataa gtcttagctt taaaaggaac
    13861 taatatgtct ttaggaagtc ccatatctat aaaagtacca atgtctgtat tatcaactac
    13921 ttttaaatgt gctacatccc caaccttagc taaaggcggt attaaagttg cagcagttct
    13981 gtcatcagaa tctttaaata tgaaagcatt tacttcatca cctatgttta tttcattttt
    14041 tccgattaat ctattatgaa gaagtatatc gtcttttgtg ttattagttt gtccatccaa
    14101 aaaatatcca aattcagttt ttctttttac tgtaagttta ttaaaatcac ctatgtttat
    14161 caaattaaaa tcatcctctc attttatatt tataatttag ccataatata cttatgtagt
    14221 agtttgtcac agtatctata ttagtattag tgaaatttac aataaataat atagttattt
    14281 atgtattttt caattctcta gcttcttata tagtataaac tccaatttct tttttgtctt
    14341 taggttttat taaaattttt acaaaataag ttaaaaagta ttgaaataaa atttctttta
    14401 aagtataatt ggtatatacc aaaattggta tataccatat cgaaaagtgg tgactatatg
    14461 aaaatagtaa ataaatctag taatatacca ttgcatactc aattaagttc aataataaga
    14521 gagatgatag aaactggtga gcttaaagag ggcgatgcaa taatgccaga aagagaactt
    14581 tgcaacatac aaaatgtaag tcgtatgaca gtaaataaaa ccattgttgg attagttaca
    14641 gaaggacttc tttatagggt acaaggtaaa gggacattcg ttgcaaagca aaaaaagaag
    14701 tatcagtttt caaatgtaaa aggttttact gatgttatga aagaaaaggg agtaaacata
    14761 aaaacggata tattatcctt tgagatggaa ctaccagatg atttagttaa aagaaagctt
    14821 ggaataagtg ataatactac aaatatatat aagattgtca gacttagata tactgatgga
    14881 gagccatttg gattagaaat agtatatcta tcagaagaaa tgtgtaaggg tctaacaaaa
    14941 gggatattgg ataattcttc attatatagg gttttaaatg aaaaatatgg ctataagata
    15001 caaaaagctg aacaggtaat ggagccagta atactttcag atgaagaaag taagcttctt
    15061 gaaacagatg aaggtgcttt agctcttaaa cttcatagaa attcctataa tagagaaggt
    15121 agccctatag aatataccat atcaatattt agaacagata aatatcaata tgaaatagta
    15181 ttgagtgagt aggtgaataa tatgaaatgt ttaattaatg gaaagataat attaaaaaat
    15241 caaatcttag aaaataaagt attagtattt gatgaaaaaa taattgatat agctgatagt
    15301 gtaccaaaag attgtgaagt tatagatgct gatggaaaat atatatctcc agggcttatt
    15361 gatattcata tacatggaaa catgggaaaa gatacaatgg attcgactga tgaatctatt
    15421 gaaacaattt caaaatcaat tatgagacat ggagtaacat cttttctgcc aactacaatg
    15481 actatggata aagaacatgt ttatgatgca cttgaagtta ttaaaaaagc ccaaaataga
    15541 aagcttgaag gggcaaaggt attaggagca catttagaag gaccttttat aaatgagaat
    15601 tataagggag cacaaaatga aaaatttata ataaattcaa aatacgaatt tataaaagaa
    15661 tataaagatg ttataaaagt tataacttat gctccagaaa aagatattga ttttgatttt
    15721 actagagaaa taaaaagatg tacagatata gttttatcta ttggtcatag taatgcaaat
    15781 tatgaccaag ctaaagaagc tataaattta ggagtaacta atgtaactca catgttcaat
    15841 gcaatgactg gtttaaacca tagagaccca ggcgttgttg gtgcagcact tacaactaat
    15901 gtgtacagtg agttaatagc agatacaatc catataaata aagatttatt tcaatttata
    15961 ctaaataata aagggaaaga aagactgatt ttaataacag attctataga agctggtggt
    16021 cttgaagatg gcaattattc tcttggaggt cagaaagtca tagttaaggg taatgaagct
    16081 agacttgaaa atggagcatt agctggaagt gtgttgtctt taaataaaat ggtatttaac
    16141 ttcttagata atacaaacct taaagtgaat gaagcaatta atttagcttc tttaaatcca
    16201 gcaacatctt tgggaataaa tgacaaaaaa ggaagcttag aaataggtaa ggatgcagat
    16261 atagctgtat ttgatgagaa tttagattgt aaaatgacac tttgcttggg ggaagtagta
    16321 tataaaaata tatagtatac aaaacaaacc ttaaagacag taaaaacaat ataaaaaata
    16381 ataaattaaa cttacattag taaaagtagt agttaaaatt taggaggaat aagatgagag
    16441 tattagtgtg taaagattat gatggaatga gtaaaaaagc cgctgaaatg atagcagctc
    16501 aaatagtttt aaaaccaaat tcaatactgg gactagctac aggaagtaca ccagtaggta
    16561 tgtatagaga tttagtaaaa aaatacaatg ataatatagt agatttttca gatgtgatga
    16621 gctttaattt agatgaatat tataagttac caatatctaa tgaccaaagc tatgattatt
    16681 ttatgaaaga gaatctattt aatcatgtaa acataaagcc agaaaatact catctaccaa
    16741 atggaatggc tgatgatatt gaaaaagagt gtatgaacta tgaagcttct atagatgcag
    16801 ctggtggtat agatgtacaa gtacttggaa taggtcgtaa tgctcatata ggttttaatg
    16861 aacctgatac taaatttgca aaaagaactc atgtagttga acttacagag tctacaatag
    16921 aagctaatgc aagattcttt aaatcaagag aagatgttcc taaaaaagct gtaagtatgg
    16981 gaataggttc aatattgaag tctaagaaaa tattgctttt agcttcagga gaagaaaaag
    17041 ctgatgcagt atataatact gtttacggag atataactcc agaagttcct ggttctatac
    17101 ttcaacttca taaagacact atagttatag tagatgaagc agcagcaagt aaactgaatc
    17161 caaaagatta taaattagta taagaataga atgtagttta agtaaaaaat agctatcatt
    17221 gagtaatcaa atttatttaa tgatagctat ttttatttaa attttttact tctttttatt
    17281 taaattagtt attattgttt aaattacttg cttattactt tttacgaaaa ctcgttatca
    17341 agaagtatcc aaataagatg ttaaaaatta ttatgtttag tgggattcta tcaagcataa
    17401 taaaattacc tataattggg atattaccaa ctggaaacat aaagaagaat acaggcatca
    17461 gtgatagtaa aaaagatgga aaacaaagaa gaagtaatct tggaatatca atataccaac
    17521 taccatcctt tttgtattct ctaatcaata attcagttcc tagtaataaa ccaataccac
    17581 cagaggaaat taaattaata aaaatgtatc ttttaaagtc ttgcatataa ccagtgtaaa
    17641 attgagtata gaaatcataa tttaatttaa cggctaaaaa atacataagc aatagaatga
    17701 ttaaaaataa aagatatcta agagcttttt tcattttaaa ttctcccttc agaaatactt
    17761 tatttagttt tattttgttg gaatctgatt ttatcattta gtttaagaaa tccataatat
    17821 tagtgaagaa tgaaataagt attatatatg aataaatatt tttagaatta aggtgaattg
    17881 tagtgcttaa tataactata atattaattg tttgaatatt caataaaaag tttgaaaaat
    17941 atcaattttg atataaactg aataaataca gttgaatatt aaattattat tttatcaaaa
    18001 atatgcaaag tactacacct tcaaatatca cctaaagtaa ttaaaaggca attaaggtga
    18061 agtagttcaa gtatttctaa aataagttta ataaattcta taataattta ttttttgcct
    18121 taaaattgcc ttaaaatcca aacaatttta aaactaatgt actataaaaa gctggtataa
    18181 tttaaatata gtaaaaaata agatttatct tatctattgg gatttaatta tttaatcaat
    18241 atatttatac catttaattt aaataaaaag tctattaagg agtgagctta tgagtaagtt
    18301 aatttatata gcagatgatg aagataatat aagaaatttg gtaaagacat tcttaaaaaa
    18361 tgaaggtcat gatgttatgg attttaaaac gggtgatgaa cttttagaac aatttaatat
    18421 aaaggagtgt gacttagtaa tactagatat aatgatgcct ggctcaagtg gttttgaagt
    18481 atgtacaaaa cttcgtgaga aaagtacagt cccaataatc atgcttactg caagagatac
    18541 agatatagat tatattacag ggataacctt aggtagtgat gattatttta caaaaccatt
    18601 tagcccaatg tctttggtta tgagagtaaa atctatattt agaaggatag agtttgaaaa
    18661 gaaacaaaat tatgataaat atagtaactc gatagatatg gaattaaaat ttggtgatgt
    18721 aataataaat aaaaagaata aaatcgttac aagtaaaaat gtaaatatag accttacacc
    18781 aaatgaatat aacctattga cttatttgtt tgaaaatata gatagagcag tttccagaga
    18841 tgaattatta aacaaaatat ggggatacga tatagaagtt gagacaaggg ctgctgatga
    18901 tacagtgaag agattacgta aaaaaatttt aaatacaaat attttaatag aaactgtatg
    18961 ggggtttgga tttaggttga aggagaaaag ttaagatgaa gaatggaaat gacaagaata
    19021 gaattggaaa gattaaatcc aaatttaaat taaagttctc aaagaaaaat ataagcataa
    19081 aaactaggat tttgttgagt atactttgtt tgataattat agtatttatg ataatattag
    19141 tatcttttaa tgtatttctt gatacatata taaaaacaac tgcgaatgaa gaattgacaa
    19201 agtctacaga aatagtagaa catatggata gtaattttag acctattaag ccaccacaag
    19261 atgatggaaa gcttcctccc aaagtattat ctaattttat gagaaatgta caagataaag
    19321 ttaggatggc agaaacacaa tcagatgctg atgctatggt agttgattct aagtataacc
    19381 tgatatttcc aacaagagag gatgatttct taaaaaatgt tgatgagatg gagctgatta
    19441 gggagtgtat tcaaaatgaa aaattagatt taaattcaga tgcaaataca cggatatcta
    19501 ccagaaataa ggattattat atttcaactg taaaaattac tagtatatat ggtgaacaag
    19561 acaagtatct tatacttttt atagacatat caaaaactct aaatctagca caaaagataa
    19621 atattgtatt aatatctgta atgtgttttg ctggaatatt agcaatattt acagctgtga
    19681 ttttatctga gaaaattgct aaaccgataa aagagttgtg tgagtttgca aaaaaaatgg
    19741 gtcaaggaga tttcaaaaga acctactttg acttttcaga taaagaatta gtagagctct
    19801 caactgttat gaataagagt gctgagtatc tggataagta tgataatgaa caaaaaatat
    19861 tttttcaaaa tgcatctcat gaattaagga caccacttat gtctattaaa ggttatgcag
    19921 aagctataaa atataatgtt atagatagta aacatgcaag tgatataatt cttgaagaaa
    19981 gtgataggtt aagtgatatg gttgaagatt tattatacat ttctaaaata gataatataa
    20041 ctaaagattt tgaacttgta gaatgtgatt taagagaagt actttcaaat tgtggagcta
    20101 ggcaaaatgt aagagctata aataagggga taaaatttat ttatgaattt gatgaagaaa
    20161 tggttttatt tgaatgtgat gaaaaaaaca tttccaaagc atttatgaat cttatagaaa
    20221 atgctttgag atacgctaag agtgaaataa aaatagtgtg taagtataat caaaaaaata
    20281 tagttgtgat aatagaagat gatggaattg gaatcaagaa agaagattta cctcatgttt
    20341 ttgaaagatt ctataaggga gtagggggaa atcatggaat tggattatca atagttaaat
    20401 ctattgtaaa taagcatggt gggcgtatat acgtagaaaa tggcaaaaaa ggagctaaat
    20461 ttactatatt atttaaattg taaaaaaatt agagaaaata tagagatgtt tgaagttgtt
    20521 ttttatatat atctgttgta tactgttgaa aaaagaacaa tattaagctg acatatatta
    20581 cgatagttga catttaaagt aaatgcttaa atatagatac gaaaggaaaa gtaaaatctg
    20641 aagtgtattt aggtttaagt aagcttctta ttttataaaa aatatgtatg aaagaacagc
    20701 tgatttttaa tattacaaat ttagtaacgg ttgtatttga agcttttgtc atccatatgt
    20761 ttttatcaga ctttttaggc cagaaagaag ggtatataaa agttgtaaga tatgctaaac
    20821 tgggttttat aatatgttta ggattctgta atttaataac tttaaaccct aaaatcacaa
    20881 tgcctttaat tttcatcctt attttttcaa catcattttt atataaagga aatttaaaga
    20941 cacgattgtt tactactgtt ttattaagta tattctttat actgtcagaa attgtagtta
    21001 caagtatttt tgttttattt gtaaaagaag gctttgaaat aatgcttgaa aataatagta
    21061 taagagtatt ggcgacaatt ttatctaaaa ttgtcttttt gttgacttgt aaaattattt
    21121 gtctatttaa aaaagatgta catttagata tgcccataaa gtattggctc cctttatttt
    21181 taatacctat atttagttta tttctgtctg tttctatctt tgatgtaagt aaatttttta
    21241 gtcttgaaag tttaaaattt ctaagcttaa tatctagtgt tggtatttta tatattaatt
    21301 ttattgtctt ttatttattt aaatttatta tagataaaac taaactatct atgaaatatg
    21361 aactacttga aaaagaaata attcataagg aagaattaag acttagtaat gagtgttata
    21421 aaattattgt tgaacagact gattctgtcg ttttcgaatg gaatatcaaa gaaaataaat
    21481 catttgtatc gcaggcttgg actgaaaaat ttggatataa caatgcatgt aagaatattt
    21541 ttaaagaaat taaagataaa gacttagttc attctgaaga taaagctata tttgaaggtt
    21601 ttcttgaaag tattaaaaaa aagaatatgc acaatcaagc agtatatcgt ttaaaaaaat
    21661 ctaatggtga atatatttgg tgtagaacat caattacaag tatttataat gatgaaaatg
    21721 aacttttaag agttgtcgga gtaattgtag atgtagatag tgatataaaa aaatatgaag
    21781 agttaagaac tagagcagaa agtgactcat tgaccaatat atacaataaa ggtacatttg
    21841 aaaaattagt ggaagaaact atagttatga atacaggtga taaaaaagat gcattattca
    21901 ttattgattt ggatgatttt aaagaaataa atgataattt tggtcatcca tttggtgatt
    21961 ttgtactaaa aacatttgct gataagatac aaactagttt tggtagtaaa gacttagtcg
    22021 gaagaattgg tggagatgaa tttgttgtat atatgcaaga ttatgttaca gaagtaaatt
    22081 tgcataaaaa agctaaagaa ttaaatagag tactttcgga taattacact gatttgagtt
    22141 ttagttttga tgcttctgtc agtataggta ttgcaaggta tcctcaagat ggaacttcat
    22201 tttttgaatt gtttaaaaat gcagatagag cactttatag cataaaagca tcaggtaaaa
    22261 attcatattg tttatttgaa gaagaactat atgtacagtg aatttgaatt tagattttat
    22321 gtgagagtaa gatttatata tacttgtggc tgtctgattt ataaaatatg ttactttgta
    22381 tatttttata tgtttcagta aggttaatta acatgagcaa aggtgtaagt aaatttatat
    22441 tagtttaagt ttacttacac ttttataaaa atacaaataa tagattcatt tacattctta
    22501 aataattaaa gctctttacc ttctaaacat gcataacata tcgttataat tccagtaaat
    22561 aagactaaaa tgcccattcc taagattaca atttcatcat ctattactcc aaatgttttt
    22621 aaagtaactt atttcgcttt gtatcataat aatttgtctc cttttacatt ttaacttctg
    22681 ctgagatttg agttagatat tcattagaat ctcgcacact tatatcatat agaagatatt
    22741 cttcataaac aaaatcccca atacgtaaat tattctgatt aaaaaaattt aataactttt
    22801 cataagtctt gtaaatagtt tcataactcc ctttatgata agcagttaca taaagtccct
    22861 ttggtttgat tgatacagga tatttcttgt actctttatt aacttttgta aataaatatg
    22921 aatatgattc aaagtcttta ttaattatat cttcaccttt aatgattgag ccaatcgtac
    22981 cataatcact caattcatag ttgtccataa agttaataca ttcatataaa aaattttctt
    23041 cctcatctcc taaaaactgt tctttatatg taacaggtgt tttgaccaag tactcttctt
    23101 catgttcttt taaagtaata gtattcgcat ctatattaca agcattttta gtgaatgaaa
    23161 tagtagattc cattagagct tgaatattat ttagtttttc aatttcattt ttaatatcaa
    23221 tggttttctt ttctaaaagc tcaattagta aattaggtgt tcttttgtct atataagctt
    23281 taatttcttt taaaggcatt tttacttccc taagtgaaga aattatacca aaaatgctaa
    23341 gttgatggta tgagtagtat ctatatccat tttctttctt taattctggt gagaaaagac
    23401 ctatatcatc ataatggaaa agtgtttttt tattgattcc acaaatcttt gcaaattctc
    23461 cagttgtaaa ataatttttt gaaacttgac tcataattat aattcctcct tgactatcct
    23521 gttacagtat agtttatcat agtatttgta aaggagtgtg attatatgaa aaaattaatt
    23581 cattttttaa aaccatatag agttttaatt gttgtagttt tgatatttac gtttttacaa
    23641 acacttggaa ctttgtatat accaacactt acagcaaata tagtaaacaa tggtgtagta
    23701 aagggagata tagattatat tgtaaaaaca ggtttaatga tgatgatagt agctggtata
    23761 acagctttat cagctgtgtt agtttgtaaa gtatcagcaa atctttcatc tggattttgt
    23821 agagatatta gagaagcagt atttataaaa tcacaagatt tatcaataaa tgattttaat
    23881 aatataggta cagcatcaat gattactagg agtactagtg atattacttt aataggtcag
    23941 tctgtgttta tgtttattca attagtatta ccagcaccaa ttataactgt ttctggtcta
    24001 ttcttagcat attctataga taaagcaatg acaattatta ttgttgtagt aatgttttta
    24061 ttcatgcttt cagcattttt agttggtaaa aagcttataa agttgtttaa aatgatgcaa
    24121 ataaaaatgg acaatatgaa tagggtgtta cgtgaggtag taactggagt aagagttata
    24181 agagctttta ataggagtcg ttttgaaaaa aagagatttg atagaactgc aatagattat
    24241 tctgaaacag caatttcaat aaataaaata tttgcagtac ttatgcctat tgtaatgtta
    24301 ataatgaatt taggtatagt aagtattatt tggtttggtg ggatgagagt cagtaatgga
    24361 aatatggaaa taggtcatat aatggcactt gttgaatatt gtatcttaat tttattctat
    24421 ttaatcatgg gagtaatggt atttatgtac atacctagag caggtgcatg tgcagataga
    24481 gtaaatcaga tattagatat agaacctgaa attgtagatg gaaatggtca taaagatact
    24541 gtctcagaga gaggacattt agtatttaaa aatgtaacct tttcatatgc acaatcagaa
    24601 gaacctgtgt taaataatat aacatttgaa gcaaaatctg gagaagtaac tgcaattata
    24661 ggaagcactg gctcaggcaa atctactatt gcaaatataa taccacgttt ttttgaaatt
    24721 caatctggag aaatatctat aaatggtcag gatattaaga agattcctca aaaagaactt
    24781 agagataaga ttggatttgt accacaaaaa gcttttttat ttagtggaac aatagaagaa
    24841 aatataaggt atggaaaaga agatgcaagt attgaagaag taaagcatgc tgcaagtata
    24901 gctcaagctg atgaatttat ttctgatatg gaagacaagt atgactcatt tgtagcacaa
    24961 ggtggaaata atttgtcagg tggtcaaaaa cagagaatat ccattgcaag agcgttagtt
    25021 agaaagcctg aagtatatgt ctttgatgat agtttttctg cattagattt taaaacagat
    25081 aaaagactta gaaaagcgtt gaaaaatgaa atcaaagatt catcagctat aattatagca
    25141 caacgtataa gtacaatcat ggatgctaat cagattatag ttttaaatga tggaaaaatt
    25201 gtaggtattg gaaaacataa agatttactt gaaaattgtg aagtttataa gcaaattgcg
    25261 gattcacaac ttagtaaaga agaacttgca taagatgaag aattaatctg atatttggag
    25321 gtgtatgata tgagtgaaaa aagaatagat gaacaagata tagaagtact tagttttgaa
    25381 gatggcatgt cagcagaaaa agctaaggat gcaaaaaaaa ctactaagag attattaaaa
    25441 tatatggcaa aacaaaagtt taaaatatta attattttta tttcagtatt gataagttca
    25501 gcgcttacag ttttagcacc tatggttatg ggaaaagcta ttgaccaact atttaatgga
    25561 ataaaaactg cagtccaaac aggtacaaaa ttcagtgtga attttagtac tatggggggt
    25621 atagtatcaa tacttctagg gttgtactta attagtgcag tatttatata tattcaacag
    25681 tatattatgt caggagttgc acaaaatcta gttcttagca tgagaaaaga tttaagtgat
    25741 aaactcaata aacttcctct taagtactat gattctcata aaaaggggga aacacttagt
    25801 atagtaacaa atgatttaga aaaagtagca gatagtttac aagaaggatt aatgcaactt
    25861 attacagcag tagttacagt agttggttct attgtaatga tgataagtat aagtgtacca
    25921 cttacaatag tatcagctat aacattactt gtttcattgg gtattactgt tgtaattgca
    25981 agaaaatcac aagaaagatt ctctgaaaat caaaaggcac taggagagtt aaatagcaat
    26041 atagaagaga tatttactgg tcaaatagtg gttaaagcat ttagtaaaga aaaggatact
    26101 ataagaaact ttaaaatatt aaatcaaaat ctttataatg caagtagaaa agcacagttt
    26161 tcgtcatatg caatatctcc aattattaga tttataaacc taattggcta tgttattata
    26221 gcagttgtag gtgggatatt tgcatcaact ggagcaatga ctcttggtag tatacaagcg
    26281 tttattcaat atgtaaatca agcatcagag cctactacag aaatatctta tattgtaaat
    26341 atgcttcaag cagcaatagc atctgcagag agagttttta cagttatgga cgaggtggaa
    26401 gagataaagg atgaagaatc ttcaaaggtt attagcatgc ctaaaggtaa agtacaattt
    26461 gagcatgtta aatttggata tagtgatgat tttattctta tgaaagatat taatatcaat
    26521 ctaaatgcag gagataagat tgcaattgtt ggacctacag gagctggaaa gacaactctt
    26581 gtaaatttac ttatgagatt ttatgagata caaggtggaa gaattactat tgatggtgtt
    26641 aatataaaag atttaaagcg tggagaactt agaactatgt ttggtatggt tcttcaagat
    26701 acatggctgt ttaatggaag tataaaagaa aatattgcat atagtaagtc agatgccaca
    26761 atggatgaaa ttgtaagagc agcaaaatca gcaagagtag accattttat aaggacttta
    26821 ccacaagggt atgacactat attgactgag gatgcttcta atctatctca aggtcaaaag
    26881 caacttctaa caattgccag ggcaatactt tcagacccat cagtattgat tcttgatgaa
    26941 gcaacatcta gtgtagatac tagaacagag gtagaaattc aaaaggcaat gaataacttg
    27001 atgaagggaa gaactagttt tgttattgca catagattat caactattcg agatgctgat
    27061 ttaatattag taatgaaaga aggaactatt attgaacaag gaagccataa ggaacttatt
    27121 gaaaagaaag gattctatga agaactttat aacagtcaat ttacaagtga atatgatgaa
    27181 gatgttgtat gattatcaag ttttaggcaa ctaaatgatt gataaatatt aagttaaata
    27241 tagtaacatg taaggttata tggaataaga gtatttctct atttcatata acctttttta
    27301 tttatcaaaa taagataaaa tttcctttct aaattagatt gaagaatgta tttatcaata
    27361 taaaagtaaa ataatcatta ttattagtga agtaaatatt gtttgccaca tatatgccat
    27421 aaagatgcac ttattttacg gagatttaac aaagtagtgt aaagtatact ctaaatataa
    27481 aataaatcaa atagagttaa ataaattgag aggtgatata aatagtgaat aaaaaattga
    27541 actatagatt tgaaatgaag cacaaaataa ctgaagcaga tgtgttagct ttaaaatcaa
    27601 gactctatcc aataatgaag aaagatgaaa atgcatctaa agatggaaaa tatcttatta
    27661 ggagtttata ttttgatact cctgaagata aagcactttt ggataaatta aatggcgttg
    27721 caataagaga aaagtttagg ataagatttt ataataatga ctgctcttat ataaggttag
    27781 agaaaaaaat caaacattac aacatgacat caaagctatc aactaattta accaaaaaag
    27841 aagtaataaa tatactaaat aatgatattg aatttctaaa agagtcgaca aattgtttat
    27901 taagagaatt ttatttgaaa ttaaaatgtg aaagattaga ggcaaaaagc atagttgatt
    27961 acaatagaga agcttttatt tatccagttg gaaatgtaag agttacaatc gatagtgata
    28021 ttaaaacttc tgtaaattcg gtagatttat ttaataaaga tttgccaact gtttcggtaa
    28081 ttgatgataa tatgactgta ttggaggtta aatatgatga atttatacca gattttataa
    28141 aggatttaat tcaaattaat aagactacct ctacagcagt ttcaaagtat gcttcaagta
    28201 gattatatat ttaagaataa aggctatgat ttatataaag atatacataa ataaggttaa
    28261 aaaacaaata agttaaaaat aaataaaata aaaaataaat aagttaaaaa taggaaggat
    28321 gattttaatt atgacattta atgatatttt taaatcaagt tttatagaaa acgtatcagg
    28381 tttttcattt gtggacagtg ctttagcact aggttcagct tttttagtag gtttatttat
    28441 atatatggtc tataaaaaga cttatatggg aattatgtat tctcgaccat tcaatgtgtc
    28501 gcttgtagca cttacaatgc ttacaacttt tgtaatattg gcagttactt caaatgtagt
    28561 tttatcctta ggtatggttg gtgctttatc tatagtaaga tttagaacag caattaaaga
    28621 cccaatggat ttagtatttc tattttggtc attgggttca ggtatagttt taggagcagg
    28681 tttgattccc ttagctgtca tgggttcaat aattatggga ttgattctaa tattcttttc
    28741 aaataaaaca atatctgaaa ctccatatat attgatggta aattgtaata atgaagattc
    28801 agaagatata gcaactgata aaattaaaaa agtatttact aaatatcaaa taaaatcaaa
    28861 aagtgttaca ccagaaaaag gaatagaatt agtgtttgaa gtaagaatga aagatggaga
    28921 aacaagtctt ataaatgact tgagtcaagt agatggagtt actaatgcag ttcttgtaag
    28981 ttataatggt gactatgtag catagagagg agtaatcttt tatgaaagat aaaaaattta
    29041 cccttcttat ctcgattatg attatatttt tatgtgctgt agttggagtt tatagtacat
    29101 ctagcaacaa aagtgttgat ttatatagtg atgtatatat tgaaaaatat tttaacagag
    29161 acaaggttat ggaagttaat atagagatag atgaaagtga cttgaaggat atgaatgaaa
    29221 atgctataaa agaagaattt aaggttgcaa aagtaactgt agatggagat acatatggaa
    29281 acgtaggtat aagaactaaa ggaaattcaa gtcttatatc tgtagcaaat agtgatagtg
    29341 atagatacag ctataagatt aattttgata agtataatac tagtcaaagt atggaagggc
    29401 ttactcaatt aaatcttaat aactgttact ctgacccatc ttatatgaga gagtttttaa
    29461 catatagtat ttgcgaggaa atgggattag cgactccaga atttgcatat gctaaagtct
    29521 ctataaatgg cgaatatcat ggtttgtatt tggcagtaga aggattaaaa gagtcttatc
    29581 ttgaaaataa ttttggtaat gtaactggag acttatataa gtcagatgaa ggaagctcgt
    29641 tgcaatataa aggagatgac ccagaaagtt actcaaactt aatcgttgaa agtgataaaa
    29701 agacagctga ttggtctaaa atcacaaaac tattaaaatc tttggataca ggtgaagata
    29761 ttgaaaaata tcttgatgta gattctgtcc ttaaaaatat agcaataaat acagctttat
    29821 taaaccttga tagctatcaa gggagttttg cccataacta ttatttatat gagcaagatg
    29881 gagtattttc tatgttacca tgggatttta atatgtcatt tggtggattt agtggttttg
    29941 gtggaggtag tcaatctata gcaattgatg aacctacgac aggtaattta gaagacagac
    30001 ctctcatatc ctcgttatta aaaaatgaga catacaaaac aaaataccat aaatatctgg
    30061 aagagatagt aacaaaatac ctagattcag actatttaga gaatatgaca acaaaattgc
    30121 atgacatgat agcatcatat gtaaaagaag acccaacagc attttatact tatgaagaat
    30181 ttgaaaaaaa tataacatct tcaattgaag attctagtga taataaggga tttggtaata
    30241 aagggtttga caacaataac tctaataaca gtgattctaa taataattct aatagtgaaa
    30301 ataagcgctc tggaaatcaa agtgatgaaa aagaagttaa tgctgaatta acatcaagcg
    30361 tagtcaaagc taatacagat aatgaaacta aaaataaaac tacaaatgat agtgaaagta
    30421 agaataatac agataaagat aaaagtggaa atgataataa tcaaaagcta gaaggtccta
    30481 tgggtaaagg aggtaagtca ataccagggg ttttggaagt tgcagaagat atgagtaaaa
    30541 ctataaaatc tcaattaagt ggagaaactt cttcgacaaa gcaaaactct ggtgatgaaa
    30601 gttcaagtgg aattaaaggt agtgaaaagt ttgatgagga tatgagtggt atgccagaac
    30661 cacctgaggg aatggatggt aaaatgccac caggaatggg taatatggat aagggagata
    30721 tgaatggtaa aaatggcaat atgaatatgg atagaaatca agataatcca agagaagctg
    30781 gaggttttgg caatagagga ggaggctctg tgagtaaaac aacaacatac ttcaaattaa
    30841 ttttaggtgg agcttcaatg ataataatgt cgattatgtt agttggtgta tcaagggtaa
    30901 agagaagaag atttataaag tcaaaataag attaaaattg aatataaata attttaatac
    30961 tgttaagtct aaatatttac ttagcagtat ttttttagaa aataatgtat ttggttaata
    31021 atataaggta ataaattgat aaaaattaaa tacagcatat taataataca taataaagta
    31081 ataaaaaaac tgtttaagta taataactta tatttagaca gtttttttca tttataaata
    31141 atataaatga aattgaaaac atttgaagga tagaaattgg ttggataaat gtataaatta
    31201 cttcaccaaa aaataatgac aaaaattgta actaagttgt aataaaatgg tagttattta
    31261 gcataaaata atgtatcata gaagtatatt ataaaattaa taaaataaga tttttgtaag
    31321 aaaactgctg gcttttgata tttagagtga gtagttaaat tatgtttagg aggggtagaa
    31381 tttgttgcaa aaagtattat ggaaattttt aaagctagta gtcggtttat ttatatgttc
    31441 agttggtata gtattgacga taaattgtaa ccttggatta tctccctggg atgtatttca
    31501 tcaaggactt tcaaatcata taggaataac tataggaact gcttctataa ttgtaggttc
    31561 tatagtagtt attgctgatg tcgttcttgg agaaaatgta ggatggggaa ctgtttttaa
    31621 catgctacta attggatttt ttatggattt acttttatat agtaatttaa ttccagaggc
    31681 tgatagttta tttgtaggaa taattatgtt gatattagga ttggttcttt tgtctgttgg
    31741 aatggtattt tatatgggaa gtggtttagg aagtggacct agagatggtt tgatggttgc
    31801 aattcaaaag aaaacaggaa aatcacttaa attaataaga ggtactatag aagttggagc
    31861 attaatagta ggatttttat taggtggaaa agttggtata ggaactataa taagtgcatt
    31921 tggattgggg tatttcacac aaatggtatt tggcttattt aaattagatt gtagtaagat
    31981 taaacataga tttatagtag atgatataaa atttatcaaa gtgtatatga gtggtgagaa
    32041 aaaggctgct gttcaaaata tagttaagta atttaagaat aaattcaacg aaatgttaag
    32101 tattttaaat taacattttg tttagataga taaattgaat attaaaagaa tattaaaata
    32161 tgaggattgc tagaacacta taaaatatag atttctagca attttttatt tgttcaatat
    32221 ttttttagta ctagaagtct tattctctat ttaatgaatg aattaattta taattagaga
    32281 tactaaactt tatagatatt aatataaaca cctttaaact gtgtattttc caaagccttt
    32341 aaaatgcttg tatttattct aaataaaaaa ataaaaaaat gtcaaaaaaa ctcttgtatt
    32401 atatccaaat tttatatata attacctatg ttgtttagaa attttaaact caatgtttag
    32461 taaacaaaat gtttagtaaa ataaaacaga aactaggagg tgcaacatgg atataggtga
    32521 aaagataaaa agattaagaa cagaaaaaca actgacccag gaagagttag ctaatagatg
    32581 tgaattgtca aagggattta tttctcaatt agaaaataac ttaacatcac catccatagc
    32641 tacccttata gatatacttg aaatactagg tacaaattta agggaatttt ttaatgaaat
    32701 agatgatgaa agaatcagtt ttacaaaaga agatatgttt gaaactgaag atgaagattt
    32761 aaaatataaa ttaaagtggt taattccaaa ttcacaaaaa aatgaaatgg agccaataat
    32821 aataacattg tatccaggag gacagtataa agaagaaaag ccacatgaag gtgaagaatt
    32881 tggatatgta ttagcaggtt caatatatgt ccatataggc gaaaagaaaa ataaagtaaa
    32941 aaaaggagag agtttttact ttagaccgaa agcaaatcac tatatatcaa acgagggcaa
    33001 aactacagca aaagtgattt gggtaagtac gccaccatca ttttagaata gaggtgttta
    33061 ataattggta gaaaatataa tagaattaag ggatatatct aaacattatg aagaacttac
    33121 tgttttagat aatttcaatt tagatataaa gaaaaatgag tttctaacat tacttggacc
    33181 aagtggatgt ggaaaaacta caacattaaa aataatagca ggatttgagt atgctgatga
    33241 tggtaaagtt ttatttgaag gtaaggagat aaataatttg ccaccatatg aaagacaagt
    33301 aaacacagta tttcaaaaat atgctttatt tccacacatg gatgtttatg aaaatgtagc
    33361 ttttggatta aaaattaaaa agactccaaa agatgtaata gatgctaaag taaaagaggt
    33421 tttgaaactt gttgcactag aaggttttga aagacgacaa gttgaatcat tgagtggagg
    33481 acaacaacaa agaattgcaa tagcaagagc tctagttaat gaaccaaagg tattattact
    33541 agatgaacca cttggagcac ttgatttaaa gttaagacaa gagatgcaaa tagaattaaa
    33601 gagaatccaa aaaaaattag gaataacatt tgtttttgta actcatgacc aagaagaggc
    33661 tcttactatg tcagatacta ttgttgtaat gtataagggc aaaattcaac aaatgggaac
    33721 accacaagat atatacaatg aacctaaaaa ttcatttgta gctaagttta taggtgaaag
    33781 taacatattt gatggaatta tgatagaaga ttataaagtt aatttctgta atagagattt
    33841 tgagtgtgtt gataaaggat tcgaaaaaaa cgaaaatata gaagtagtaa taagaccaga
    33901 agatataaaa atggtaaagc cagaagaagg aatgttaaag gggaaagtta catctacagt
    33961 gtttaaagga gtgcattacg agatagaatt gaatgaaaat ggaagattgt ggatacttca
    34021 taatactaaa aatgctgagg ttgggactga actaggcatg gatatatatc cagaagatat
    34081 ccatataatg agaaaagaga ataactaaga tgaaaagaaa atctttttta gcatatccat
    34141 atgtagtttg gagtgcgata tttgtaataa ttcctttaat attagtagta ttttttagtt
    34201 ttacaaaaga atcaggtgga ggttatgcct ttacacttga gaattataaa gaagtaattg
    34261 accctatata tatgaaagtt tttgggcgtt ctattctttt agcaggagga gctacattaa
    34321 tatgccttat agttggttat ccagtggcat atataatttc aaaggctcgt gtaagtagaa
    34381 gaggttcatt aatattattg tttattcttc ctatgtggat gaactttctt ttaagaacat
    34441 atgcatgggt tgctatatta ggaaaaaatg gacttttaaa tacattttta ggttggtttg
    34501 gaatacaacc attagcaatt ttgtatacta attttgccat acttttaggt atggtgtata
    34561 actttttacc atttatggtt cttccaatat atacagcact atcaaagatg gataatgatt
    34621 tgataaacgc tgctcatgac ttgggtgcaa ataatatgac agtttttaga aaaattatat
    34681 ttcctttgag tttgccaggt gtaatgtctg gaataactat ggtatttatg ccagcagtca
    34741 ctacttttgc aatatcaaga ctgttaggtg gaggtaaaat aatgctggtt ggagatttga
    34801 ttgaacaaca gtttacagtt gttggagatt ggaactttgg ttcagctata tcgatattta
    34861 tgatgatagt aatattaata tctatgtcta taatgtcaaa atttggagat gaatctgaca
    34921 aagaaggcgg tgggttacta ttttaaaatt aaagaaaata acttctaata tatatttagc
    34981 attagtattc ttatttttgt atgcacccat atttgctttg gtactatttt ctttcaatga
    35041 ttcaaaatca atggcaagat ggaatggatt tacatggaag tggtatggtc aattacttca
    35101 aaatgagagt ataatgagtg ctttatatta tactattgta atagctatat tagcatctgt
    35161 aatatctaca atagtaggaa ctataagtgc tataggaata cataagatga gaggtaagag
    35221 taagaaatta atactaaatg taaactatct tcctatttta aatacagaga tagttacagc
    35281 agtagctctt atgagtctgt ttgtatttgt aaaaatggaa tttggattta caacaatgct
    35341 attggcacac ataatgtttt gtttgccata cgttatactt tcagttttgc caaaaatgaa
    35401 gcaattacct gataatatag aagatgcagc tatggacttg ggagcaacac ctatatacgc
    35461 tcttagaaaa gtaattttac cacaaataaa accaggtata gtttctggat ttttaattgc
    35521 atttactatg tcaatagatg actttataat aagtttcttt aatgctggaa atggtgtaag
    35581 caatctttct atagaaatct atggaatggc tagaagaggt ataaaacctg aaataaatgc
    35641 attatcaaca ataatgtttg cagtggttct aggtttactt ttactagcta ataaaaaaga
    35701 atctatagta agggggatta aataatgatt aagtttaaaa aagcaatatc ccttatagct
    35761 gtaggtatga tgatagttac tttatttaca ggatgtaata aagcaactga ttctacaaaa
    35821 gttttaaatg tatataatgt tggagattat atagatgagt ctcttataga taagtttgaa
    35881 aaagaaacag gaatagatgt tcaatattca acttatgata ctaatgaaat gatgtatcaa
    35941 aaagtaaaga gtggtagtac acactatgat ttagtatttc cttcagacta tatggtagag
    36001 aaaatgaaaa atgaaggtct tttggaaaaa ttagatttta agaatatacc taatatgaaa
    36061 tatttagata agagtttttt aaatcctgta tacgacaaaa ctaatgaata tagtgttgca
    36121 tatatgtggg gaactcttgg aatattgtac aataagaaag aagttaaaga ccctatggat
    36181 agctggaata tactttggaa tccaaagtat aagggaaata taatgatgtt tgactctgtt
    36241 agagatacta tagggataac tcttaaaaaa ttaggatata gcatgaatag tgtaaatcca
    36301 aaagaaataa atgaagctaa aaatctttta atgaaacaaa aggatttagt attggcttat
    36361 gtaaatgatg agggtaagga tagattactt ggtggagaag tggcaatggg tatgctgtat
    36421 tctggagatg cagttacact aatggagcaa aatcctgacc ttgattatgc tatacctaaa
    36481 gagggaacta ataaatgggt agatgctatg tgtgtaccta caacagcaca aaataagaaa
    36541 gaagctgagc tgtttataaa ctttttatta gacccagaga atgcaaaagt aaatgctgag
    36601 tacattgggt attcaacacc taatacagga gcactaaaat tattagaccc agaaataact
    36661 cagaatcctg ttgcatatcc atctaaagaa gtacttgata aatgtgaaac ttttgaagat
    36721 attggtgaaa atataaaatt atatgacaag gcttggatag agttaaaatc aaaatagggt
    36781 cttgttggtt taagtaaatt tacttaataa atacttaata aaactgttct tttttagaaa
    36841 atttattttc taattattga acagttttat tttttgttta agttatattc atatgcaatt
    36901 taaatagttt attaataaat gaaaacttat ttgtataatg actttaataa taattagaaa
    36961 aactgggcaa cttaatagaa taattggagg tgtaaattta taaaaaatga ataggataaa
    37021 taaaaaaata gatttattaa tattggcttt gctcgttttt atatttttaa ttgttggaat
    37081 agtaatacta tcgattagga cagaaaataa attgaatgtg ttcataatgt tagcaataat
    37141 tttttttata ataatgttaa cttatttatc aaattcagta gtggggttga taacaagttc
    37201 aataattata tttatgtata catcctatat tttatataac aatattactc acaatatgga
    37261 tgttgaattt atatcatata tgtggataat agcaacacca gtatcttcaa ttataatggg
    37321 taatctgaac aaaagcataa atgaattgca aaatacaaat aaaaaactat ctgaacagta
    37381 taaggaatta gtgactattg atagtgaaac tggacttaga aatttaaaga ttttttataa
    37441 tgatgtaaat atggagataa gtaaatctat tagacataat actgattttt ctcttatgat
    37501 agtaaaatta ccatactacg gaaacctaca gactatattt ggtgaaaaca aaactaataa
    37561 aatagtaaaa tatattggtt caaatattat agaatgtaca agaaatgaag atataattta
    37621 tagtttacaa aaagatatga tagggatact aatgccaaat acatctttgg aaggttcaaa
    37681 agttgttaaa gacagaataa agaaaaggat aaaagaatta aacttagatt taaacaatag
    37741 gggaaaatat gtaaatatag atgtcaaaat tgcattttta caatataaga gtagttttgg
    37801 agatagtata aattttaaga atatagttga agaggaactt caatatgatg tttaaaatat
    37861 ttaataaaag tctattaaaa ttagtagttg tattatcaat agtactgaca atatcaaatt
    37921 ttagcttatc ttcatacgca tcagaaatta cttccagcac agataaggta ttaatcatat
    37981 atgattctaa gaaagaaaca gcttataata gagatatttt aaatattatg aggactctat
    38041 tgggaagatt tagttcagat atagagctat taaaattgag taactatgat ggtgagataa
    38101 ataaaaatta ttacagtcat atatttattt taggaatcaa tgaaaactca tataataatg
    38161 ataaaaacac taaaaacttg attagttcct taaattcata taaaggaact atatgttggt
    38221 taggatatgg tatagaaaat cttttggaac ataaaaaata caatttagac tatgtaggaa
    38281 aaacaaacaa tatagttagt gtaaattata gaggtaaatc atataacttg gatgaacatt
    38341 atgtttttaa cattgtagaa tcaaaagata caagtaataa agtaatagga agtattaatg
    38401 ataccttaaa taagtatcca tatataataa atgataaaaa tcttttttat gtatcaaaat
    38461 tagatttaga tggagtttta ttttatatat tttgcgattc acttaatgat atttttaaca
    38521 ttaagacgtt tgataaagga cgtatatttg taagaataga agatgtacat gcttttagag
    38581 aaccaaaaaa tcttgtagag atagcggatt atttaagtag taagaatata ccatttacga
    38641 ttgcattaat accagcatat gtaaatccta aaaatcataa agtaataact ttatcagaaa
    38701 gccctgaaat tgtcaaagca ataaaatata tgcaagataa aggtggaact gtgatattgc
    38761 atggatatac tcatcaatac aagaaagaag aagtttctgg agaagggtat gaattttggg
    38821 atggtaaaaa agatgaaccc ttaaaagaaa atatgaagat atttgtcaaa gatagagttt
    38881 tgaatggtct tagagtatgt atagagaatg gaatttatcc tcttgcattt gaagcgccac
    38941 attatgcaat ggaatcagag ggatataaag aattaaaaaa atatttttct acttatatgg
    39001 ggcaacatca aaataatgat aaaaaattta gcacaaatac atatccttat attattaggg
    39061 atacagagga gtttaatata tttatacccg aaaatttagg atatatagac ccagaagata
    39121 agtttacttt tcaaaatata aaagaaaatt tagataaatt atctattgta agaggtttta
    39181 gtggagggtt cttctttcat tcatatttaa acatagagta tctaaaaaac acaatagaat
    39241 atttagaaaa acagaatata gaatttatga atttaagaga ttttaataat tgggtaaaag
    39301 ttgatgaaat acaaataaga aataatggag atgaaattat agtcaactat gataaggatt
    39361 tagatgaaat aactaaaagt gatactagat ttaaatccat atccaatatt agtaaaattt
    39421 taatattcat agtatctata agtgttttaa tatttgtgat tatatttata tattttaaga
    39481 gaatagataa aaagaaat
//
LOCUS       DAEOTL010000032        39444 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEOTL010000032 DAEOTL010000000
VERSION     DAEOTL010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39444
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.032"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            292..2481
                     /locus_tag="KRH82_001947"
     CDS             292..2481
                     /locus_tag="KRH82_001947"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBG8655226.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2549..3316
                     /locus_tag="KRH82_001948"
     CDS             2549..3316
                     /locus_tag="KRH82_001948"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBG8655227.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3374..4390
                     /locus_tag="KRH82_001949"
     CDS             3374..4390
                     /locus_tag="KRH82_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBG8655228.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4456..4704
                     /locus_tag="KRH82_001950"
     CDS             4456..4704
                     /locus_tag="KRH82_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655229.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4880..5377)
                     /locus_tag="KRH82_001951"
     CDS             complement(4880..5377)
                     /locus_tag="KRH82_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBG8655230.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5621..6685)
                     /locus_tag="KRH82_001952"
     CDS             complement(5621..6685)
                     /locus_tag="KRH82_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655231.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVFDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIDLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6688..7785)
                     /locus_tag="KRH82_001953"
     CDS             complement(6688..7785)
                     /locus_tag="KRH82_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655232.1"
                     /translation="MKLYMSVKTMLKSLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7799..8734)
                     /locus_tag="KRH82_001954"
     CDS             complement(7799..8734)
                     /locus_tag="KRH82_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655233.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINGLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSVIDKNNSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8863..9510)
                     /locus_tag="KRH82_001955"
     CDS             complement(8863..9510)
                     /locus_tag="KRH82_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655234.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9503..10666)
                     /locus_tag="KRH82_001956"
     CDS             complement(9503..10666)
                     /locus_tag="KRH82_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8655235.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10850..11194
                     /locus_tag="KRH82_001957"
     CDS             10850..11194
                     /locus_tag="KRH82_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBG8655236.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11225..12826
                     /locus_tag="KRH82_001958"
     CDS             11225..12826
                     /locus_tag="KRH82_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBG8655237.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     RKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12845..13945
                     /gene="dprA"
                     /locus_tag="KRH82_001959"
     CDS             12845..13945
                     /gene="dprA"
                     /locus_tag="KRH82_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBG8655238.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13978..16065
                     /gene="topA"
                     /locus_tag="KRH82_001960"
     CDS             13978..16065
                     /gene="topA"
                     /locus_tag="KRH82_001960"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBG8655239.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16230..17015
                     /gene="codY"
                     /locus_tag="KRH82_001961"
     CDS             16230..17015
                     /gene="codY"
                     /locus_tag="KRH82_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBG8655240.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17122..18387
                     /locus_tag="KRH82_001962"
     CDS             17122..18387
                     /locus_tag="KRH82_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBG8655241.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNNAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNGDF"
     gene            18418..19188
                     /locus_tag="KRH82_001963"
     CDS             18418..19188
                     /locus_tag="KRH82_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8655242.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNVKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19297..19743
                     /locus_tag="KRH82_001964"
     CDS             19297..19743
                     /locus_tag="KRH82_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBG8655243.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19761..20954
                     /gene="nifS"
                     /locus_tag="KRH82_001965"
     CDS             19761..20954
                     /gene="nifS"
                     /locus_tag="KRH82_001965"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBG8655244.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEESIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            21008..21448
                     /gene="nifU"
                     /locus_tag="KRH82_001966"
     CDS             21008..21448
                     /gene="nifU"
                     /locus_tag="KRH82_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBG8655245.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21737..22816
                     /gene="mnmA"
                     /locus_tag="KRH82_001967"
     CDS             21737..22816
                     /gene="mnmA"
                     /locus_tag="KRH82_001967"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBG8655246.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22959..23197
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23265..25904
                     /gene="alaS"
                     /locus_tag="KRH82_001968"
     CDS             23265..25904
                     /gene="alaS"
                     /locus_tag="KRH82_001968"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBG8655247.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25929..26186
                     /locus_tag="KRH82_001969"
     CDS             25929..26186
                     /locus_tag="KRH82_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBG8655248.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26196..28367
                     /locus_tag="KRH82_001970"
     CDS             26196..28367
                     /locus_tag="KRH82_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655249.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28573..28998
                     /gene="ruvX"
                     /locus_tag="KRH82_001971"
     CDS             28573..28998
                     /gene="ruvX"
                     /locus_tag="KRH82_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBG8655250.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            29076..29363
                     /locus_tag="KRH82_001972"
     CDS             29076..29363
                     /locus_tag="KRH82_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBG8655251.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29645..30103
                     /locus_tag="KRH82_001973"
     CDS             29645..30103
                     /locus_tag="KRH82_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBG8655252.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30220..30957)
                     /locus_tag="KRH82_001974"
     CDS             complement(30220..30957)
                     /locus_tag="KRH82_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBG8655253.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31174..32850
                     /locus_tag="KRH82_001975"
     CDS             31174..32850
                     /locus_tag="KRH82_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBG8655254.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            33056..33256
                     /locus_tag="KRH82_001976"
     CDS             33056..33256
                     /locus_tag="KRH82_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBG8655255.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33310..34473
                     /locus_tag="KRH82_001977"
     CDS             33310..34473
                     /locus_tag="KRH82_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBG8655256.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNTLIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34684..35106)
                     /locus_tag="KRH82_001978"
     CDS             complement(34684..35106)
                     /locus_tag="KRH82_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBG8655257.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35127..35963)
                     /locus_tag="KRH82_001979"
     CDS             complement(35127..35963)
                     /locus_tag="KRH82_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8655258.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36261..36857
                     /locus_tag="KRH82_001980"
     CDS             36261..36857
                     /locus_tag="KRH82_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBG8655259.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            36887..37606
                     /locus_tag="KRH82_001981"
     CDS             36887..37606
                     /locus_tag="KRH82_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBG8655260.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37608..38147
                     /gene="scpB"
                     /locus_tag="KRH82_001982"
     CDS             37608..38147
                     /gene="scpB"
                     /locus_tag="KRH82_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBG8655261.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENKLIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38309..38938
                     /locus_tag="KRH82_001983"
     CDS             38309..38938
                     /locus_tag="KRH82_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBG8655262.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38892..39320
                     /gene="ytfJ"
                     /locus_tag="KRH82_001984"
     CDS             38892..39320
                     /gene="ytfJ"
                     /locus_tag="KRH82_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBG8655263.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
BASE COUNT        15807 a         4198 c         6777 g        12662 t
ORIGIN      
        1 tttctaaata cttattaatt aatcaaagtt aaaatgaaaa aaatataaaa aaataaagta
       61 tataagagta taatttgact tttatatact tttttatatt atttttgagt tttttaggaa
      121 gatattttac aagttaagaa aactataagg agtgttatat tgaatataaa atagtataat
      181 atatattatg ttagataatt aatatgaaaa tatacaaata tataaaaagt ttgtttagag
      241 ttatagttaa tgtgtgtatt aatttaatac taatttattg gaggtttaaa aatgaagtac
      301 ataataaaaa gagatggtac aaaagaactt tttagtaaaa gtaagattga agatgctgtc
      361 tataaagcta gtataaatag tgaaggtggc gtagatagag agttggcata tgatatatca
      421 agaaaaatag ctaatgacta taattctatg gaaaaatgct tatccgtaga agaaatacaa
      481 gatatagttg aagtactact tatggaatca aatagaaaag atatagcaaa acactacata
      541 ttatatagag aaagacgctc tgaaataagg actaaagctt gggagtttga tgaattacaa
      601 aaatcaatat ggaagaacaa gtatagacat aatggtgaga gttttgatga atggataaag
      661 agaatttcaa ataatagttc aagaatatca aaactaataa gacaaaaaag atttctattt
      721 gctggaagaa ttttagcaaa tagaggatta cagaaagagg gaaaaaaagt aacatattct
      781 aattgttatg taatagaacc accaaaagat agcatagaag atatatttga tactgcaaaa
      841 aaacttgcta gaacttttag ttatggtgga ggagttggaa ttgatatttc aaagctaaga
      901 ccaaaaggag cgaaagttaa caatgctgca aaacatacga ctggagcagt ctcttttatg
      961 gaactttaca gtatgacaac tggcttaatt ggtcaaagag ggagaagagg agctcttatg
     1021 atttctatgg atgtaaatca tccagagata gaagacttta tagatataaa aacagatttg
     1081 gagaaggtta ctaaagcaaa tatttctgta agagtaacag atgaatttat gcaagctgta
     1141 agagaaaaaa agttatataa ttgtactttt gaagttgaaa ctactggaga aaaaatagtt
     1201 aagatagtaa atgcttatga tttatttaat aaatttgtga aaaataactg ggattatgca
     1261 gaaccaggta tattgttttg ggataaaata aaaacatata attttatgag tgaagataag
     1321 aacttttgct tttcaggagt aaatccttgt gcagaagaac cacttccaag tggaggaagt
     1381 tgtctacttg gctcaataaa cttgtcagag tttataatac aaccatttgg tgaacatgct
     1441 acttttgata ttaataaatt aaaatcttgc gttagagaag ctgtagtagc tttaaatgat
     1501 gtcttagatg agggattgaa cttgcatcca ttacaagaac aaagagatag tgtacataag
     1561 tatagacaga taggtttagg tgtaatgggt atagctgata tgcttataaa aatgggaata
     1621 agatatggtt ctgatgaatc tttagaacta tgtgatttaa ttggtaagac tatgttaaat
     1681 gaagctgtga agcaatcagc attaattgct aaagaatatg gaacatttag tgagtataaa
     1741 tatgaaaata tttctaaatc taagtttttt atagaaaatc taaatgaaga cactaaggaa
     1801 atggttaaaa agtatgggct tagaaattca caacttttaa ccatacctcc tacaggttcc
     1861 atatctacaa tgataggtat cagtggtgga atagaaccta tatttaatct ttcatatata
     1921 agaaaaactg aaagcttgca tgatgaggat gtgtattata aagtatatac tccaattgtt
     1981 aaagagtata tggacaagaa aggtattaca gatgaagaat gtttaccaga tttttttgtt
     2041 actgctatga atataggata tgaagaaaga ataaacatgc aaaaagtatg gcaaaagtat
     2101 attgatgctt ctatatcatc tacaataaat ataccttttg aaactacagt tgaagatgtt
     2161 ttcaatatat atattaaggc atgggaggct ggtcttaaag gagtaacaat atttagagat
     2221 ggatgtaaaa ggagtggaat tttaataaat gaaaaaaagg aagaaaataa taaagaagat
     2281 aaaaaagaaa atagtaaaaa agaatattat aaaaataata aaaaagaaaa agataataaa
     2341 gatgaaaaag ccaaagaaat aataaataaa aattttgaag aagatgaaaa atttgtgtgc
     2401 cctgagtgtg gaagtgaagg aattgcacat acaggtggat gtagtatatg tttaaaatgt
     2461 ggctatagtg gatgcaatta aactctaatt aaaaaatttt aatatattta aaaattaaat
     2521 ttttaaaaac gaaagatgag ggaatggtat gcaggataaa agtgtgaggg agattaaaga
     2581 aataatagag actttagaag tagaaaaata tatggaatat atagagctgt taagagttga
     2641 tgaaagaaaa tctgtacaag gtctagctat aaaactggca aaaaagctgg ataatattag
     2701 aaaagaagaa gaaagattgg aaactataaa tatatttgag aacgaaggct atgataaagg
     2761 ttatttatat attggaggaa ttgatgaggc gggaagaggg ccacttgctg gacctgttgt
     2821 agcttctgtt gtagtattta aaaaagatac caaaatagaa ggtgtaaatg actctaagaa
     2881 actgagtgag gcaaaaagag atgaactttt tgaagtaata aaagaagaag cactagatta
     2941 tggaataggt atagtaaaca atgaagaaat agatgaattt aatatattaa atgctacata
     3001 tatggcaatg aaaaaggcta taaattgttt aaaaaaagca ccagattatt tattagttga
     3061 tgcagcaaca ataccaggta ttgacatatc tcaaaatcca attgtgaaag gagattcaaa
     3121 atctatatca atagcagcag caagtatact tgctaaagtt actagggata gtataatgta
     3181 ccaatatgat agagtatacc cagaatatgg gtttaaatct cacaaaggat atggaactaa
     3241 agaacactat gaagctattg aaaaatatgg cataactcct atccacagaa aaagtttttt
     3301 gaaaaatata ctgtaaatat aatatgatat aatgtatata atataaatta ctatagttaa
     3361 tgggggatta aagatggaat ataatgaatt attaaaaagt gctagagaaa atttaaatgg
     3421 aagttgtaaa gtttgtaagg tttgtaatgg ggttgcttgt gcaggtgaag tgcctggcat
     3481 gggaggtaaa ggaagtggtt cttcttttat agaaaatagc aagagtttag aaaaagtaaa
     3541 agtaaatatg agagtaatac atgatgtatc aaatcctgat acatctatag agatgtttgg
     3601 aaagaaaatg agtgcaccta tatttgcagc tccagtaaca ggaactactt taaatatggg
     3661 tggaaaaatt aatgaaagag attacataga accagtagtt gcaggatgtg ctaatagtgg
     3721 tatttatgca atggttggtg atacggcagt agatgctttt ttaatggaaa atttagatgt
     3781 agtcaaaaag tataatggag ctggaattgt atttattaaa ccttgggata atgaaaatat
     3841 tataaaaaag ataagattag ctgaagaagc tggtgcattt gcagttggag ttgatataga
     3901 tgcctgtggt ctagtaactt tatcattaca tggaaaacca gtacttccta aaaatgttaa
     3961 acaaataaag gagttagtaa agtctactaa actaccattt atattgaaag gtataatgac
     4021 tgttgaagat gctttaatgg cagtagaagc aggtgtggat gcaatagttg tatcaaatca
     4081 tggaggaaga gtgcttgact gtacaccagg agcatgtgaa gttttaccaa aaattgctga
     4141 tgctgttaaa ggtaaagtta caatacttgc agatggtgga gtgagaactg gtttagacgt
     4201 actaaaaatg ataggtttag gtgcagatgc agtattaata ggaagacctt ttgtgactgc
     4261 ttcttttggt ggtgcaactg atggtgtaga aacttatgta aataaacttc aatcagagct
     4321 aagtagttct atgatattaa ctggatgtca aactataaaa gatattgatg gaaaagttat
     4381 atacaaataa aattttatac aaaaaagagg aaaaatcatt ttaatgtaga ataattgtac
     4441 aaagggggaa tttatatgag tagaaaagct tatgaagaag ccttagtaga attagaaaaa
     4501 tttattgatg aaagaaaaga aataattaaa agtgcggagg actgtattga taagtacata
     4561 gttgacagaa cgctaccttt tgattacaaa gataaatgtg tggaatggca acaagagtta
     4621 cttgatattg cagaggcaca agttttagaa gcaaatgaat taagtgtatt attacaagag
     4681 aaaaaagaac ttgaagaaga ttaaatttta ttagctaaga gtaaatcagt aatatgattt
     4741 actcttagtt ttttttattt gaataaaata catctatcta attgagataa ctttattaat
     4801 attagattag gcagtttaaa ataagctaaa gtagcatgga tgattagtat aaaaaataaa
     4861 accagtttaa aaaactggtt taatttgtat tctttgaatt taatatatgt tttttcattt
     4921 cctctaatac cattgtatag gatttacatt gagcagcagc taattctgat aaagcaaatt
     4981 tttgagcttt atttaaaaac tccttatctg tgctacacaa ttgttttgaa ctgtcttgta
     5041 tcataagcat tttgattaat tttacaattt caaaaacatc tcctgaatga aatttatctt
     5101 ggtacagttt aagtctttct tttctatcaa aaatccatac accatctgtt ttattaatag
     5161 attggataaa attatcaaca tcatttccat ccataactgg acgtatgcca attctatctg
     5221 catttagaac tggaatcgaa attttaaggt tactattaaa aatgacactt aattcatagt
     5281 atttttgcat ctcatgattt attttctttg ttacaatatc atttacagag caggctccct
     5341 cttttggata cattacactt tcaccaattt tatacatatg ctagttatac ctccaaattg
     5401 aattttagat attgcaactt aggtacaatg ctttaattat ctaatgatta atattataac
     5461 ataaataact tgacaagtca aaaatattaa tatataatat aaagtttaga cttggtgatg
     5521 tgtgaaacta aagagaaaaa tataagataa aataatttaa tatgttgaaa tattctttta
     5581 caattatata aaaatagata ctaattatat ttaataatta ttagttttta gcaaaatctc
     5641 ttagtttaag acttcctgca gttacaaata taattccaat taatattaga gctattatat
     5701 ttattaaaat actaccattg tttttaatag catctatagt ccaataaaat ggtgtgaact
     5761 ttgaaagatt agtcataaag gataatttat ccattgatgg tattagacta gagatagata
     5821 tagctagatc tattaaagaa taaaatgtag atataagact tatagaactt tcatttttaa
     5881 atactctagc tacccaaaat acaaatccag tggaaacaaa actatttgct agtacaatca
     5941 tcaatacatt cagactcaaa ttaaagtctt ctataattga aaaacataat agagcaaaag
     6001 tgtatacaat tgattgaata aaaaatagtc ctaaaaatat actgaaaatt atttttatat
     6061 ctttattatc tgtagagata agtcttttta gcacatttga tttttttaat gtaaataaat
     6121 cagaagcaag atgtgccgca ttaatataca taaaatagca tatcaagaag actactaaaa
     6181 atgaaccttt attcttatct ggtttgttat caattatatt tgtctttgtc aatttatcat
     6241 ctatattttt atccactttc aattttaacg atttagtaat aaaagattct atttgtgatt
     6301 ctgcccaaag actaccacca ccattttcaa ttttaaagca tttaactaca ggtcgttgta
     6361 atttatctat actatttgaa aaatttttat ctaaaacgaa tacagcagaa accttattat
     6421 tttttaatag attcatagcc ttatcttgtt catttaatct aaatgaattt tcttttaatt
     6481 tagaactatt tattaactta tgttcatact ttcctgaaga gtcaaataca attgctactg
     6541 gagaaaagta cattgattga tttcctgagt tgttgataaa aaaattaagt gaaaaaatta
     6601 gtataatagg aagcataacc atattaatta aaagagtatg attttttaga tatcttttta
     6661 tatttgcaat agttaatcta atcattatta aacctccctc catttatatt tttcctttac
     6721 aatagcaagt gcaattaata ttgtagagat aattaaacat gtgaaaatta aatctcctat
     6781 tgaatctata gttttaaatg tttcataatt actaaacaat tctcctatta aataggtagg
     6841 agataaactt gtaagcttag taaatgtatc acttatcata ctgaagatac ctccaaaaat
     6901 tgtctgtaaa aagagtaatg cataaactat tgctgtaccg tattttttac taaaaaagct
     6961 ggttacaaag gtagatattg aagtcataaa ataagatgat aaagcacaaa gtaggagcaa
     7021 tatggcaaaa ttacctttaa atgttattcc aagtattcta aagaataaaa catataataa
     7081 taagaatata aatgaataaa tccataaacc tacaaagtca taaattaaga attgtactct
     7141 agttataggc atagaataaa gtctttttga aagtcccttt gattcactta tataatttga
     7201 caaaatattg ttcattataa aaattattac aagaaatcct agtgaaacta aagcaaagta
     7261 ttcataagag ttctgtttaa cattgttatt tattatagaa gtatcaatag aatttttatt
     7321 aaataattta gaaaaatctt ctgaacttat tttctgagaa ttatttaaat aaaatttttc
     7381 atggtaagta tctaatatat cttgaagcaa tattgcaata tcatcacgag ttccaagttt
     7441 ttctatgttt agagtatttg atttttcatt taataaacta ctctcatagc ctttaggtat
     7501 agtaagcttt aattctgcct tagaatcatc ttttttaact gttaatatat aagataaatc
     7561 atttttcaaa tactttgtca aatcatttga taatcttgtg ttatctttgt catatataac
     7621 aatgggggta gattctgttt ttatagggtt ttgaaacatg ctttctgtaa ccatcccaag
     7681 aaaccaagat aaaatcagag gcaaagctaa aaaatatatt aaattaagta taaaggagct
     7741 ttttaaactc tttagcatag tttttacact catgtataat ttcataaaat cacctccatt
     7801 agtcccttaa attttttcct gttagattta aaaatacgtc ttctaggcta ggttcttcat
     7861 aagaaatttt cattattttt gaattgtttt tgtcaataac agagagtata tctgtaagtt
     7921 gtaatttttt atctatatcc aattctaata atgaattatt ttctaaaaca gatataacac
     7981 ctttagtatt ttttaaatca aagataagtt gggcatttat attttttatt tccataatca
     8041 attttgtatt tgtagatacg agtgatttta aataatcatt atctccaaaa gcaatttctt
     8101 taccttcatc cataataaaa attttagaac aaaggtgttc aacttcttcc atataatggg
     8161 aagtatatat tacagtagtt tcatgttttt tagatatatc ttttataaaa ttgaaaatat
     8221 gatttcttga ttgggggtct acacctacag ttggttcatc caatattaat attttaggat
     8281 gatttaagag tgctattcca atatttaatc tcctttgcat accaccagat aattttttga
     8341 cctttttctt tttgacttca gtaagacctg taacttctaa tgcttcaatg attctttctt
     8401 taagtagttt tccctttaaa ccgtagaaag ctccaaagta ctctaagtta tcaaaaggag
     8461 taagagtttc tataattgct aattcttgtg gaactaaccc tattatagac tttgctttta
     8521 tataatcttt tgataaatct aaaccattga tttgaatact accactattt ggtaacataa
     8581 gatttgtaat tatatttata agtgtagatt tacctgcacc atttgggcca ataagtccaa
     8641 atatctcacc ttttttaaca gaaaagctga tgttatcaag tactaattta tcattaaatc
     8701 tttttgttat attatttact ctgactatat ccatagtaat ccctccaaaa taattttgta
     8761 taagttaaaa agctataata ttataataaa gaattgtgaa ttataattct attactataa
     8821 gtcactaaaa aaagtgactt aagtcacttt atatttttag atttattcta ttacaatttt
     8881 atttttgaaa gcaaagattg ctagttgagt tctgtcacga agttctagtt tagctaaaat
     8941 attagttatg ttattcttta ttgtaccttc agataagaat agttcttgac ttatttcttt
     9001 attattaagt ccatttgcaa ttagtctaat tatagatatt tctttttctg ttaaattgta
     9061 catgtcataa agatgctctt gtttaaccgt tttttcagag gtcatgattt tttcagctac
     9121 acttttatca agcacaatat tgccaaaaaa tgaagaacga atcccttcat gcaatacttc
     9181 atcagagcta tcttttaaaa ggtatcctga agcaccaaac ttcatagcat cttttatata
     9241 ttcatcatca ttaaaagttg ttaaaattaa taatgttata gaattattat attcctttat
     9301 aagccttgta cctagaaccc catcacatac tttcattcgt atatccataa gaactatgtc
     9361 tacatcattc attttacaaa attctaaagc ttcatatcca ttagaagcat ctcctacaat
     9421 ttctaaatca ttataagatg ataatataat tttaagacct tttctaatta atttttcgtc
     9481 atctactata agaactttaa ttttattcaa aaaaatcacc ccctgaaaat ttaggaaaag
     9541 aagctctaat tgtgaaacca ttattagaat tatcaaattc aactttacca tttaattcat
     9601 atattctctc attgatacta ttaagtccat ttcctttttt tatattgcca catcctatac
     9661 cattatcact aatagtaatt ataagatttg aagtattgaa tgtaataaaa attctgattt
     9721 cagttgcctt tccatgccta gatgagttgg aaagggattc ctgtatgagt ctatataaag
     9781 ctatagattg atttctggat aagttccaag tattttttga aatagttaat ttaacattaa
     9841 tatttgtaag cttaataaag cttttaacta attctttgat tttaaataaa ctttggtaat
     9901 tttcatattc aacaggtttt aactcagata tagcccttct tacatcttga aaactttcag
     9961 ttacaaattc tctaagttca tgtactaagt cataaattag aggtttgtct tttaagagtt
    10021 tttctatagc atttaattgt attattgttg tagaaagaga atgtcctaca ctatcatgta
    10081 tttctcttga tattcgattt ctttctttta aaattgctaa ttcttctata gaacttgcat
    10141 aagtttccaa atcagcatta acttttttta attcatcttt agaaattcta agcttatcat
    10201 aaagattttg actgtataat tttgataaat tctcattttc tatatatata gaaagtacag
    10261 ttataattag caatatagag cttgactcca gtgccaaata tatattttta tctaaactaa
    10321 taataagaga agatattata acaaaagaga acaatatgta cttatatttt tcctttatta
    10381 aaaatgatat atctaatatt aaaggaacaa agtaaatcga attaaaagtt tttgtataat
    10441 tacaaagtat aaaaattaat ataagttcta aaaagtaaga aataagtata aatttattct
    10501 catttgataa agaaaaaaat ctaacttgat tatttattat aattagaaat aatattatca
    10561 tagttatgac cggatacaat gtattttcaa catttttcaa atagcttaca actaatataa
    10621 ataaagataa atatcgtata aaagcaacta atttttctct gttcattaaa ggcactcctc
    10681 caaaaaaata aacttttcct atgaaaacta gaataatatc ataaaagaat aaagtcaata
    10741 gaagtattta ttaatattga tggaaataaa atcaatccaa aaacttgaat agtaaaattg
    10801 tatactgacc ataatttaaa agtgaaaatt taatgtattg gagtgaataa tgaataataa
    10861 agaaaaaggt gattttggag aaaaagtagc agttaattat ttgctatcaa aaggagcaaa
    10921 gatactagaa aaaaattaca gattaaagat aggggaaata gatataatag caaaaatgga
    10981 agatgaaatt atatttgtgg aggtgaaatc aaggtctaac ataaagtttg gctacccttg
    11041 tgaatctgta agcttcaaaa aaagaaaaaa gataattgga gttgcaagtt attatattat
    11101 aaaaaataac ttaaataaca ctcccataag atttgatgtt atagaggtat atttattaga
    11161 aaaaagaata aatcacataa tgaatgcttt ttaaaaaaga taatgttttt ggaaaggatt
    11221 aaatatgtta agtattatta attcaagcaa cttagtagga atcgacagct ttttagttaa
    11281 ggttgaagta gatgtaagca atggaatacc tagttttaat attgttggtc ttccaggcaa
    11341 agaaattaaa gaagcaagag aaagagtaaa gtcagcaatt cttaatagtg gatataaatt
    11401 tccaagcacg agaatagttg taaatttatc accagcagat ataaaaaaag aaggagcttt
    11461 tttagattta tctataagta taggcctttt aagagagtta ataaaaaaag atgaaaatta
    11521 cataagagaa agtatgttta taggagaatt atcattagat gggaaaataa gaaaagtaag
    11581 aggtatattg cccataatta tgggtgcaaa aactcagaac ataaaacgta tttttatacc
    11641 aattgagaac ataaaagaaa gtctatttgt agatgaaatt gatataattc ctattaaaag
    11701 tttaaaagaa tgtgtcgatt ttttaaacga agagataaaa gtcgataaag taaggataat
    11761 gtcttttttg gatgataagt caagaaaaga gaacgaagaa ttagaaaaag ataatagtta
    11821 tatagattgc aaatatacta agattaataa tgaagaaagt aaatatgatg aagactttaa
    11881 agatgtaaaa ggaaattatt ttgtaaagag gagtgcagaa attgctgctg ctggaaatca
    11941 taatatgttt atgattggac ctccaggctc aggaaaaact atgattgcaa aaagagtaag
    12001 gacaatttta ccagatataa gtgtagaaga aatgatagaa gtaagtaagg tctatagtat
    12061 attgggtatg ataaatgaaa ctaaaggaat aattgataaa agacctttta gagcacctca
    12121 tcatacaact acaaagcaat ctttaattgg aggaggaatg gatgcaagac ctggagaaat
    12181 tgctttagca catagaggta tcttattttt agatgagata gccgaatttg atagaaaaat
    12241 acttgagact ttaagacaac ctatagaaga tggatatgta aatatatcca gagtaaagta
    12301 cagtgcaaaa tatccttgta gagtactgtt agttgcagct atgaatccat gtccatgtgg
    12361 ttattatatg tcagagacag agtgtagatg tagaagtaac gaaattgata gatacataaa
    12421 taaaatatca ggtccattgt tagataggtt tgatattttt gtagaagtta attctataaa
    12481 atattcagat tttaattctt taaaacaaga agaaagctct caaaaaataa agagaagagt
    12541 agaaaatgct agaaaaatac agataaatag atttaggaag gataatataa aaaataatag
    12601 tgaaattaaa gcttacaatt tatttaaata ttgtaaactg gaaaaagaag cttcaaaaac
    12661 ggctgagatg atatttaata aatacaacct aagcagtaga agttatacaa aacttttaaa
    12721 aatggcaaga acaatagcag atttagaaga aagagatttg ataaattcac agtgtattat
    12781 agaagctttt tcatttagaa aggcttatta tagttatttt aaatagtttt ttgaggtgga
    12841 ttttatggaa aaaagagata cttatttatg gttaaaatca attggtggaa taacaacaaa
    12901 aacaattgaa ataatagaaa atgaaatagt aaatattgaa gatatatttg atttttctga
    12961 aaaagaaata tataatttaa aaaatataag cttgaatatt agaaaaaata tagtaaaata
    13021 tagaggtcac gcttatttag aaaatataaa agaactactt tacaaaaaag cgattaaata
    13081 tatttgtaaa tatgataaag aatatcctga aaatttaaag aatatataca acgctccaaa
    13141 gttattattc tacaaaggtg acataggttt agttaataat aattttaata tagctatagt
    13201 aggttcaaga aaacctacag cctatggaat taattgtgca aaaacaataa gttgtcaact
    13261 atcccaatat ggagttaata tagtaagtgg attagctata ggaatagatg catactcgca
    13321 cataggttgt atgagtggaa aatctaaaac tatagcagta cttggttcag gagtagacaa
    13381 tcctcttcca aaacaaaatt tacatttatc aaataaaata ttagaaaatg ggggattatt
    13441 attatcagag tataatatta actcgacagt agccccgtac catttttcta atagaaatag
    13501 aattatcagt ggtttaagtg atggagtagt tgttgtagaa gcagcaataa aaagtggtgc
    13561 actaatcaca gtagattttg ctcttgaaca tggaaaaaat gtttttgcaa tacctggtaa
    13621 tataaattct caaatgagta gaggttgtca taaaattata aaagaaggtg caaaattaat
    13681 tgaaaatata gatgatattt taaatgaata taacatattt aatattattg ataaaaaaat
    13741 aaatcaaaaa tatgataata taagtctaaa tgccaagtct aagcaaataa ttgaagctat
    13801 aaaaagagaa ggaaacttgc atatagatag tatttgtgat tatactggta tagaaataaa
    13861 gtatgtaaat tcaataatca atgaattagt actaaatgag ttagtagtag aaatgaataa
    13921 taaaacgtac agtttaaatg tataaattaa gattaggtag tgggggtgta tggttttatg
    13981 gccaaaacat tagtcatcgt agaatcgcct gcaaaagcta aaactataga aaaattttta
    14041 gggaaaagtc attacacagt taaagcatca gttggtcatg tcagagattt acctaaaagt
    14101 aaattaggtg tagatataga aaataatttt gaacctcaat atataaatat aagaggaaaa
    14161 ggcgatgtaa taaaagaatt aaaaaaagaa gctaaaaaat ctaaacaagt atatctagca
    14221 actgaccctg atagagaagg tgaagctata tcatggcatt tagctcatat actaaattta
    14281 gatgaatctg aggattgtag aatagagttt aatgagataa ctaaggatgc aattaaaaaa
    14341 gcaattaaac atcctagaaa tattgatata aatttggttg atgcacaaca ggcaagaaga
    14401 gtgctagaca gacttttagg ttatcaaata agtcctatat tatggcaaaa ggttagaaaa
    14461 ggtcttagtg caggtagagt gcaatctgtt acaacaaagt taatttgtga cagagaaaaa
    14521 gaaataaagg catttattcc aaaagaatac tggacaatag atgttgaggc taagacagta
    14581 aaagacaaag atataacttt gaaattttat ggtaaaaatg atgaaaagat tgaattagaa
    14641 aatgaagaag ctgtaaatga aatactaaaa gaaatggaag gtaaagattt aaaggttgag
    14701 aagatagaat ctaaatcaag acgtaaatca gctccaaaac catttacaac aagtatgctt
    14761 caacaagaag gagcaaataa gttatttttt actactaaaa aaacaatgat gatagcacaa
    14821 gaattatatg aaggtatcga catagaaggt gaaggtactg ttggtcttat atcatatata
    14881 agaactgact ctaaaagaat atctgatgaa gcaaaagaaa aagctaaggg ctatatcgta
    14941 aacaatttag gagaaaacta ctataaaaac actggtgata aaaaagaaaa aaaggatact
    15001 aaaaaggttc aagatgccca tgaggcaata agaccaacct cagttgatag aactcctgag
    15061 agtataaaag cctcattgag caaagaccag tacaagttat acaatttaat ttggagaaga
    15121 tttgtagcta gtcaaatgga agattcagtg tttgatatac taaatgtaga atgtaaaata
    15181 ggcgatattg tatttaaggc aactggttca aaaatgaaat ttgatggtta taccaaggta
    15241 tataattttt cagaaagaga agacaaaatt ttaccaagta tagaaaaagg agatatatta
    15301 aatatagaaa atatattgcc agaccaacat tttacacaac caccagcaag atatacagaa
    15361 gctagtttag taaaaacact agaagaacta ggtataggta gaccaagtac gtatgctcca
    15421 acaatagcta ctatactgaa tagagagtat gttgaaaagc aaggaacaag tctatgtcca
    15481 acagaacttg gaataatagt tactgatatt ttggaaaata atttccataa atttatagat
    15541 gtagatttta ctgctgatat ggaaagtaaa cttgatgtta tagaagaagg caatacagat
    15601 tggaaaaaga ttgtatcaga atcatatgca ccacttaaag aggctattga agaagctctt
    15661 gaaaatatag aaaaagtaaa tatggatgaa gaaactgatg agatttgcga gaactgtggg
    15721 tctaatatgg ttatcaaata tggtagattt ggaaagttta tggcttgtaa aaactatccc
    15781 gattgtaaaa caactagacc aattatgaat aaaattggtg ttaaatgtcc aaaatgtgaa
    15841 gaaggagata ttatacttag aaaatctaaa agaggtaaag ctttttatgg gtgttctaat
    15901 tatccaaact gtgactttgt agcttggaat aagccaacag gagagttttg tgagaagtgt
    15961 ggttcatata tggttgaaaa agtgactaaa tctgaaacaa aaacagtgtg ttctaataaa
    16021 gaatgtaata aagagacaaa agagcataat gacggaaaag agtgaaaatt gaaaaaaatc
    16081 acataattct cttgaaaaag gttccaatct atgataatct ttcaagtgta aacaactaat
    16141 agaaaaataa attttcatta aatgtgaaaa taatattaga aaatataaaa ggttattaaa
    16201 aggcctaaat ttcatgagga gatgattaaa tggcaagtga agtgttacaa aaaacaagga
    16261 aaataaataa aacattacaa acaagtggtg gaagcagtgt ctcttttgat ttactggccg
    16321 gagcattggg cgacgtttta agttctaatg tttatgtagt aagtgcaaaa ggtaaagtac
    16381 taggtcttca tttaaatgat gttcaagaca gttcagttat agaagatgag tatactaagc
    16441 aaaagaaatt ttcagatgaa tatactcaaa atgtgttaaa aattgatgaa acattagaaa
    16501 atttaaatgg tgagaagata ttagaaatct ttcctgaaga acatggaaga ttacaaaaat
    16561 atactacagt agttccaata ttaggaagcg gtcaaagatt aggaacattg gtactttcaa
    16621 gatattcaaa ttcattcaat gatgatgatt tagtaatagc tgaatacagt gcaactgttg
    16681 ttggtcttga aatattaaga gcaataggtg aagaattaga agaagaaatg agaaagaaag
    16741 ctgtagttca aatggcaata ggcactctgt cctactccga gcttgaagca gttgaacata
    16801 tttttgctga attggatgga aaagaaggtc tacttgtagc aagtaagata gctgatagag
    16861 ttggtataac taggtctgta atagtaaatg cacttagaaa atttgagagt gcaggtgtga
    16921 tagaatcaag atcattaggt atgaaaggta ctcatataag aatacttaat gacaaactta
    16981 cagatgaatt aaaaaaatta aaaaacaatc aataatctat attttatagg tttagattag
    17041 aaaaggtatc tatttgaaat agataccttt tttagacgaa ttattaaggt aatgataagt
    17101 atattaaaaa ggagtgagaa aatgccttta gcagataaaa taagaccaaa aacaatgaat
    17161 gatgtaatag gtcaaagtca tataataggt aatggaaaaa tattgtctaa gatattacaa
    17221 tctaattttt taccaaatat gatatttttt ggtcctcctg gtgttggtaa aactacagta
    17281 gcggaaataa tagcagaaag aagcaataaa agcttctata aaataaatgc tactaattca
    17341 tctttagaag atataaaaaa ggtgatatca gagcttggaa gtataaataa tgtaaatgga
    17401 gtcctattat atatagatga aatacaaagt tttaataaaa aacagcaaca atcaatatta
    17461 gaatttatgg aaaatgggag tataactttg attgctagca ctacagaaaa tccatatcat
    17521 tatgtatata aagctctttt aagtaggtct actgtatttg aatttaaacc tttagaaaaa
    17581 cttgatatag aaaaaggact gaaaagagct gttgaagtat taaatgaaga tagctatatg
    17641 gatattgagt gtaataataa tgctattgaa gatatagcaa ttctttctga tggagatatg
    17701 agaagagcct taaatatttt agaagtggta gtctattcaa ctaaaccaaa taaggataat
    17761 ataacttata tagattcaga tgtaataagg gcatctacat ttaataaaat tataaactat
    17821 gacaaaaatg gtgatagtca ttatgatatt ttaagtgcat ttcaaaaatc tataagagga
    17881 agtgacccac aggcatctat acactatcta gcaagactta taaaaggtgg ggatttgata
    17941 agtatatgta ggagactttt agtaatagct agtgaagata taggcttagc ttatccaaat
    18001 gctattgtaa ttgtaaaggc atgtgtagac tcagctatgc aacttggatt tccagaagcg
    18061 aaaataccat tagcagaagc tactattctt ttggctacat ctccaaagtc taattctgca
    18121 tgtatagcaa taatgaaagc tatggatgaa ctggataaag agtttgttaa ggatatacca
    18181 aatagtataa aggatgctca ctattctggt tctaaagaaa taggtagggg ttgtggatac
    18241 aaatatcctc ataattttaa aaatcattat gtaaagcaac agtatttacc agatagcata
    18301 aaagatagta tttattacat accacaagaa aataaaactg agaaaaatat aaaaaaatat
    18361 ttagaatatc taaatggtga tttttagact gaactttatg tatcgggggt agatattatg
    18421 attataaaac ttaactcaac ttatcacagt agagttatga aatacttaaa aaaagaacct
    18481 gagtacaatt tgtttataat aggggatatt gaaagatatg gatatggaaa taatttttta
    18541 aatatatggg cagatgtggg tgaacatggt gaaataaagg caatattact taaatatttt
    18601 gaatttatga tgttttattc tgatggagag tatgatgttg aaggttttta taatctactt
    18661 cgtaatacta attacgaaga aatatctggg aaaatatgtg ctgtagatgc tttagcaaag
    18721 agattaggac ttaataattt aaaggtagtt gatttttgca aacttcaaac taaaaagttt
    18781 ttgatagata ataattgtaa tgtaaaggtt aagagaatta gacttggaaa tctaaaaaag
    18841 acagtaaaac tttatgactt aatagatgaa tttcacagta caactttaga gaatttaaaa
    18901 aatggactaa ggacaggtag aggatattgt atagagatta acaaacaggt ggtgtcaatg
    18961 gcaaagagta cttcagaaaa taggactcat gcaatgataa ttggagtagg aacacatcct
    19021 aaatatagag ctaaaggact tgctacaaaa tgcctaatta aactatgttc agagttactg
    19081 agagaaaaca aaattccttg tttgttttat gataatgaag aggctggaaa gatatataaa
    19141 aaactaggat ttgaaaacat tggaaaatgg ggaatttatt caaaataaaa aattaaaatt
    19201 aatcttgaca aaattagtag ggtataataa aattatcttg aaagtaattc ctactaaaac
    19261 agtatgaatt agatttctat atagaggtga taatatatga agttgtctac taaaggtaga
    19321 tatggactaa aagcaatgtt tgaattagca ttaaatcaag acaatggacc agtatcatta
    19381 aaatttattg ctaagaagca aaaaatatca gatcagtact tagaacaaat attttcatct
    19441 ttaaaaaaat cgggtctagt aaaaagtgtg agaggtgctc aaggaggtta tttgctttca
    19501 aagaatgctg aagacataac agtaggagat atacttgtag tattagaagg accagttgca
    19561 ttatctgact gtgtactaga tgaagatgta tgtgaaaact caaacatgtg tgtaacaaaa
    19621 atagtttggg aaaagatgaa aaagggtata gaagatgtta tagattcaat tactcttaaa
    19681 gatatgataa atgactataa caaaaataaa ttagaaaatg atataacaaa tattaaaaaa
    19741 tagatttgga gatgaatgta atggaaaaaa gaagattgta tatggattat tctgcaacaa
    19801 cacctattaa aaaagaagta ttggatgcaa tgatgccata cctaacagat tattttggta
    19861 atgcatctag ttttcacaca ttcggaagag aagcaaaaga tgctttggat aaagcaagag
    19921 aacaagtagc agcccttata aatgctgaac ctagtgaaat atattttaca gcaggtggtt
    19981 cagaaagtga taactggaca ctagagggtg tagcttatgc taataaaaac aaaggtaatc
    20041 atataataac ttcaaaaata gaacaccatg caatacttca tacatgtgaa tacttagcaa
    20101 aacatcatgg atttgaaata acttatttag atgttgatag cgaaggaaaa gtagacttaa
    20161 aacaactaga agagtcaata aaagatacta ctatacttat aagtataatg tttgcaaata
    20221 atgaaatagg aactatacag cctattaaag aaatatccga aatagctaaa aaacataaga
    20281 tattattcca cactgatgca gtacaagcta caggtaatat tccagtagat gttaaagaat
    20341 taggaataga tttgatgagt atgtcttcac ataaaatata tggaccaaaa ggtgtaggag
    20401 ctttatacat aagaaaaggt gtaagacttc ataactttgt ccatggtgga gcacaagaaa
    20461 aaagcaaaag agctggtaca gaaaatatac ctgcaatagt tggatatgga aaagcagcag
    20521 aattagctaa ggaaaatatg caaaatcatg tagaaacttt aactcgtctt agaaataagt
    20581 taatagatgg tgtgttagaa agaatacctt acacaagagt aaatggtagc ttagaaaata
    20641 gattgccagg aaatgcaaac tttgcattcc aatttataga aggtgaagga atacttttat
    20701 tattagatat gttaggaatt gctggttcaa gtggttctgc atgtacttct ggttcattag
    20761 acccttcaca tgtacttctt gcaataggtt taccacatga aatagcacat ggttcattaa
    20821 gacttacagt tggagatttt acaacagatg atgatataga ttatatacta gagaacttac
    20881 caaaagtaat agaaagactt agaagcatgt caccacttta tgatgatgcg aagaaacaag
    20941 gtttagtaaa atagacataa agataaagca taaaaaatag acataaattg agtaggagga
    21001 aaagataatg caatatagtg ataaagttat ggaacatttt atgaatccaa gaaatatggg
    21061 agaaattgat aatgcaagtg gtgtaggtga agttggaaac cctacatgtg gagatataat
    21121 gaagatattt ttagacatag atggagatgt aataaaggat gttaagttta aaacatttgg
    21181 ctgtggttca gctatagcaa gttcttctat ggcaactgaa atgataaaag gaaaaactat
    21241 aaaagatgca ttagaactta caaataaagc tgttgcagaa gctttggatg gtttaccacc
    21301 agtaaagatg cattgttcag ttttagctga acaagctgta aaagcagctc ttatagatta
    21361 tgctcaaaag aacaatatcc atataccaga attggatgga tatgttatag atgatgctca
    21421 tgaccatgat gttgaagaag aagaataaaa ataagtgatt gtgttatgag aagtttacaa
    21481 tgattaaaaa gaagtactaa tgatataatt aggacataaa aaatagctgt ttttaaaatg
    21541 gctatttttt attgcctaaa ttaagtattt taacttgatt tagaggttaa ttagttaaca
    21601 aaataatcca taagattcaa ataataaaga tgattatttt tttagaaaat agaacaagct
    21661 atattttaaa taagtacaat acttgctcta tatggtataa taataagtaa tgcaaaagat
    21721 gaggtgaaat ttgtttatga ataaaaaagt aatgataggt atgagtggag gagttgatag
    21781 ctctgtagct gcatatcttt taaaacaaca aggatatgat gtcattggtg ttactatgaa
    21841 gttgtggcaa gatgatgatg ttgttgaaat tgaaggtggt tgttgttctt tatctgctgt
    21901 tgaagatgct agaagggtag caaataaaat aggtatacca ttttatgttt taaattttag
    21961 agaagtgttt aaagaaaaag taatagatta ttttatagat gaatatttgg aaggaaaaac
    22021 tcctaatccc tgtatagctt gtaataaaca tataaaattt gatgattttt ataagaaggc
    22081 tagacaaata ggttgtgatt atgtagctac aggtcactat gcaaagatag aaaaggatga
    22141 aagtacagga agatatttgc taaaaaaatc tgttacagat aaaaaagacc aaacttatgc
    22201 actttataat cttacacaag agcaactaga gcatacttta ttgccaatag gtgactatga
    22261 aaaagataga gtaagagaaa ttgctaagga aatgggtatg gcagtacaca ataagcctga
    22321 tagtcaagaa atttgttttg ttaaagataa tgactatgca aattatgtaa aaaaacattc
    22381 taaaaagcgt attgaagaag gtttttttgt agatactaaa ggcaatatac ttggaaaaca
    22441 taagggtata ttatattata ctataggcca aagaaaaggg cttggaatta cttttggaaa
    22501 accaatgttt gtaatagaca taaatccaat aaataatacc atagttcttg gagacaatga
    22561 agatttattt aaaaaggaac ttattgctaa agatgttaac tttatatcaa tagatacgtt
    22621 agaagaacca ttaagagttc aagccaaaat aagatattca gcaaaaccat caccagctac
    22681 tattcataga gtaggagaag atactattaa aatagttttt gatgaagctc aaagagctat
    22741 tactaaaggt caatctgtag taatgtatga tggagatatt gtagtaggtg gaggtataat
    22801 cgagaaaagt ttataaaaac atctaaaaaa ttaaaaaaat aaacaataaa gtatattaag
    22861 agtaaataaa gtttataaaa taaatttatt gtatatgaaa atatagtatt gattaatttt
    22921 gtaaaattta gtaatataat tagtatatta attaaaaaac aaatacagtg ataaggaata
    22981 gtaaaatatt tgatgtctta cagagagagg gaaatgctgg aagcccttag aatatgatat
    23041 ttgaagcagc cttttagtag caatcttgaa caatttatat tttataaaga agatttaagt
    23101 agagattgac ggtagttacg ttatagctaa ggttttccga agatatcata ctttgtatga
    23161 taattagggt ggtaccgcga ttgtcctcgc ccctataaat ttatttatag ggacgaggtt
    23221 ttttatttaa acgaaaaaat aaaatttatt aggaggaaca tgatatggaa aagatgggat
    23281 taaatgaaat aagaagtaag tttttagaat tttttgagtc aaaaggtcat tatgtagcaa
    23341 atagttattc tttagtacca aacaatgata agagtttgtt acttataaac tcaggtatgg
    23401 cacctttgaa aaactacttt tcaggtgtag aagtacctcc aagtgtgaga atgtgtacat
    23461 ctcaaaaatg tataagaaca ggagatatag aaaatgtagg tataactgca agacatgcta
    23521 cattctttga aatgatgggt aacttctcat ttggagatta ctttaaaaga gagtcaatca
    23581 aatggggatg ggaatttgtt acagaatggc taaatatacc agaagataag atatgggtga
    23641 ctgtatatga agaagatgat gattcttatg atatatgggc aaaagaaatg aatttcccag
    23701 aagaaagaat ggttagactt ggaaaagatg ataatttctg ggaaataggt acaggtcctt
    23761 gtggtccttg ttcagaaata tattttgata gaggagaaga atatggatgt gacaatccag
    23821 actgtaaacc aggctgtgat tgtgataggt atttagaatt ttggaaccat gtatttactc
    23881 aatttgatag agatgaagaa ggaaattata gtctattaga aaacaagaat atagatacag
    23941 gtatgggtct tgaaagaatg ggttgtatta tgcaaggcgt agacactatc tttgaagttg
    24001 atacaattaa atctatacta gaagcagttg agaagttaac aggagtaaaa tatggagaga
    24061 atccaaaaaa tgatatatca ataagaataa taactgacca tataagagct gtaacattct
    24121 tagttagtga tggagtgctt ccatcaaatg aaggaagagg atatgttctt agaagacttc
    24181 ttagacgtgc tgctcgtcat ggtaagttat taggagtaaa agaattattt ttacagaaac
    24241 taatagatga agttataaaa gtaaatgata aagcatatcc agttttagtt gaaaaagaaa
    24301 gttatattaa aaaagtagtt ggaatagaag aagaaaaatt caatgaaact atagaccaag
    24361 gaacagaaat attgaactct tatatagaag tattaaaaaa tgaaggaaag actgtcctaa
    24421 gtggtcaaga agcttttaaa ctatatgata cttatggctt ccctatagac ttaactaaag
    24481 aaatattaga agaagaacat ctatctgtag atgaagaagc ttttaatgaa gaaatggaaa
    24541 agcaaaaaga aagagctaga aatgctagag gaaatatgga tggagaaagt tggaaggaag
    24601 accctctatc aaaattagaa tctacagttg acagtacatt taatgggtat agtgaaattt
    24661 atggtgaagg aactattgaa gctatagtta aagatgatga gctagttcaa agtgcagaag
    24721 aaggcgataa ggtatctata gtactagata acactacttt ctatcctgaa ggtggaggac
    24781 aagttggaga ttgtggattg ataactaatg aaaacttagt tttagaagta ttaaatacta
    24841 aaaaaggtgc taataatagt ataaaacata taggtataat aaaatcagga agaataagta
    24901 atggggacaa agtaaagaca ctcgtagata gagaaactag aatgtcagct gcaagaaatc
    24961 acagtgctac acatttactt cataaggcat taagagaagt attaggagaa catgttaatc
    25021 aagctggttc tttagtaact ccagaaagac ttagatttga tattactcac tttgaagcaa
    25081 tatcaaatga agaattaaaa gtaatagaag aaaaagtaaa taatgttatt ttatcatctt
    25141 tagacataaa atgtgatatt atgaatataa aggaagctaa agaaaaagga gctacagcac
    25201 tatttggtga aaaatatggt gatgaggtaa gagtagtttc tatgggagat tattctacag
    25261 aactttgtgg aggaactcac ttgacaaata cttctcaagt aggaatgttc aaaatattat
    25321 ctgaaggtgg agtagcagca ggtgtaagaa gaatagaagc aataacagga aaagctgttt
    25381 atgaatacct aaaagaaaga gatggaatta tctctgaagt ttgtgtaaac ttaaaatcta
    25441 aagaagataa tttaattcaa agaataagtt ctttattaga agaaaataaa aacttatcta
    25501 aagaattgca tgatatgaaa gctaagatga gtttacaatc agttgattct atttttgatt
    25561 ctaaagttga agtaaatgga gttaatttga taactaataa atttgaaggt atggatatgg
    25621 atacactaag agaaacagca gataatctaa gagataagct tggttctggt gtagtagtac
    25681 ttgcaaatgt agtagatgat aaagttaact ttgtagttac tgccactaaa gatgtattag
    25741 ataagggaat acattcaggt aatattgtta gagaagttgc aaaaatagct ggaggaaaag
    25801 gtggaggaag acctaatatg gcacaagcag gagctagtga tgtatctaag gttgaccaag
    25861 ctttaagcta tgcaagtgag gttattaaga cacaagttaa ataacattca ctcaaggagg
    25921 tttttagttt ggaaaaagat ttagactaca ctatgaaatt tgaaggaata ccagaagata
    25981 ggatgagtgt aggagatact attgattttg tatataaagc attagttgaa aaaggatata
    26041 accctataaa tcaaattata gggtatctcc tttctggtga ttctagctat ataactagtc
    26101 ataaaaatgc aagagctata attaaaaaat ttgaaagaga tgagatactt gaagaagtaa
    26161 tcacgcacta tctgaataga aagtaggtca aataaatgag aaaaaagatt atgtcgttgt
    26221 ttgcaatagt cattatgatt tttgtatcaa ctgctagcta tggttttgct gaagaaaaag
    26281 gcaaggtcat atttattgat atgaatagga ccaatcttgg aagtatgatg aatattccaa
    26341 tcttgaaaaa tgagatagaa aagagaggct atgtagctct catgaatata agaggggatc
    26401 aaggtactga tgatagaagg tcttatgcaa gtatgggtgc aggaacaaga gctagtgtaa
    26461 ctactgaaga ctatatcaat tttcaaaaag tagaccaaga tactgctaaa gcttttgaag
    26521 tcgcaacagg tcaaaaagct aaagaaataa atgatttagg cattaataga tctataaatg
    26581 aaaatcttga gtatggagaa tatggagcaa atttagggtc attaggaaaa actttatcag
    26641 aaaatggttt aaagacatct gtaattggaa atgctgatat aattgaaaat aatcaattag
    26701 ttaaaaacag aaacttatgt ttagtagcta tggaccaata tggaaggatt gattcaggta
    26761 atattgataa tattaataag aaagattcta aaatgccatt tggaatatct acagattatg
    26821 ataaattact agatgaaact aaaaaatcct ataaaaatag tgatgctata tttgtagaac
    26881 ttggagatac atatagatta gatatgtata gattaaatct aaatgataat acttatgata
    26941 caatgaagaa aaatattgta aaaaatataa ataaatatct tgaacaagta ttttctatgg
    27001 ttggagaaaa tgacactgtt tatatagcaa gtgcatttcc aagtgaccta gattataaga
    27061 ataagagaag actttctcca ataataaaat ttagtggaga agggaaaggt ctactggaat
    27121 ctgccacaac aagaaaagct ggaattgttg ccaatttaga tgttggagta gatatactag
    27181 gtacatttgg tcttgaaaat aaagagatgg taggtagaag ttatacttta gtaaataaag
    27241 aggacaatat tagctatcta aaatcacttt atgaaaggat agtgtctata tcttcaataa
    27301 ggtcaactat tataaatggc tttgtaggcg taatatctgc ttcttgggta attgccatgt
    27361 ttgcgatttt ctttagaaat tatatgccac ataaagagcg tgtattcaaa gtacttaagg
    27421 agtttataaa attaggcata ataatgccac tatcatttat gttagctcct ttgatgaatt
    27481 ttaaaactcc aatttcaata tctttgggaa tatttgcaac tacgctaata ttatacttgt
    27541 taggtagaaa attatttaag gacaatgata taaagcacat gggatttttt gcaacactta
    27601 ctattttagt catagttata gattctgtat ttggaacata cttaatgcaa aataacataa
    27661 tgagttatga tgctgtcata ggagctaggt actatggtgt aggaaatgaa tatgaaggtg
    27721 taactatagc aagtgcagta tttggcttag cagtattatt acattataag aaggtatcta
    27781 aattacttgt tgtaattttt tcattaataa tacttataac tagtgcatat ccttcaatgg
    27841 gtgcaaatgt tggtggagct atatcagaat gtgtagcata tttgttgttt ataatgctta
    27901 tatatgacat taaaatagat tttaagaaag ctgtattatt agctgtttca gctgtagttg
    27961 tcgtttttgc atttgcagct ttagatatac tttcaggtag tgaatctcat ttaggtatgt
    28021 ttgtacagag aattttccta aatggaccag gagagatatt acaaacattt ggaagaaaaa
    28081 ttcaaatgaa tatgcaacta gcacagacaa gtgtatgggt aaatatttta cttgtaggaa
    28141 ttggagtaat tgcagtgctt atatttaaac catctagaca ctttagaaag ataatgaata
    28201 attttccaat cttgtttaaa gggtttattg catctatggt tggttgtata attactcttt
    28261 tagttaatga ttctggaata gttgctgcat ctacagcatc tatatatata cttataccac
    28321 taataataat aagtataaat atgataatat ttgaaaaaaa taactaaaaa aatttttact
    28381 gttcatatag gatttaaata aaaaatgcaa tatgattatt aatgtaaact ggatgcttac
    28441 ataaaaaatc atattgcaat ttttatgatt gattatgtaa aattatatga agcagtaagc
    28501 ctgtgacctt agttatgaga ggttcagaat atgtatttaa tctatagaat ataaatagat
    28561 aaaggaggaa ctatgttaga tggaagaata atgggtcttg atgttggtga taaaactatt
    28621 ggagttgctg tgagtgattt gatgggatta actgcacaag gtgtaaaaac aataaaaaga
    28681 gttggcaaga aaaaagatat tgaagagcta aaagcaataa taaaagaaaa acaagtaaat
    28741 aaaattgtat caggattacc aaaaaatatg aatggaactt taggtccaca aggagaaaaa
    28801 gtaatcaagt tttgtgaatt ggtaaaagca gaaacaggta ttgatgtaga gttttgggat
    28861 gagaggcttt ctacagtagc ggcagagagg tctttattag aagcagatgt tagtagacaa
    28921 aaaagaaaaa aggttataga tatgttggca gcagtaataa ttttgcaagg atatttagat
    28981 tttaaaataa attcataaaa gaactataaa attgaatact tatgatatat aatataaata
    29041 ataaaaataa aaataaattt gaggtgaatg acattatgga agaaaatata ataaatttaa
    29101 tagacgaaaa tggcgttgaa agccaatttg aaataatatt aacattagaa gcagaaggaa
    29161 aagagtatgc aatattaatg cctttagatg atgaagaagc agaagaagct ttaatcttta
    29221 gaattgatga ggatgaagaa ggtgaaatct taataccttt ggaaagtgat gaagagtatg
    29281 aaactgttgt agctgtgtat actgctataa tggaagaaga aggtttaaat tacgacgaag
    29341 atgaatcaaa tggacttaac tagataagta attaagtttg tatataaaaa tcagatattt
    29401 attatatttg ctttaattaa accttattaa ttgtaaaagc atttatagta tatatctgtt
    29461 tttttgtttt ttattaaaaa taccaaaaaa tttatgaatt ttggtgaata atatatcttt
    29521 tatgggtata tatttatatt atgagaataa attaaattta tttaaatgtc ttgacaaaaa
    29581 atgaattatc aattacaata ttatttaata aagattatca attgaaaata gtaagggtga
    29641 tgttatggca aatacaatgg atttattaaa agacaagtta aaagaaactg gttttaagat
    29701 tacgccacaa agaagagcaa tagttgaaat attgcttaaa catgaccatt cacatctaag
    29761 tagtgaggaa atctatgatt tagttagagt tgactgtcct gaaataggct tagctactgt
    29821 atatagaaca atgcagctat tggatgaaat aggattaata tcaaaactaa acttagacga
    29881 tggatgtata agatatgaga ttagtctaca taaagaagac tgtcataatc atcatcatct
    29941 tatttgtaaa aattgtggaa agataatgga agctaaagaa gaccttttag acaatataga
    30001 aaaagagata caatcattgt acaaatttaa aatacttgat catgatgtta aattttatgg
    30061 actatgtgac gagtgtaatg gagtaagcga ttcagaagaa taaacttcta ttgcttaatg
    30121 tcgatggaag aatagtatag aacttttata ttctatgcta ttcttccatt ttttattata
    30181 aaccatctat aaaatgcaaa tatacagttt tcaagatgct tatagtttta atattgaaaa
    30241 tataattaat cctataagta caaaaatgaa tgatttttct atgaaattac taaatggtcc
    30301 tccaacagtt aaaaaaccta aagaaatttt cttttcgctt agcggataaa aaattggtat
    30361 tccttgcttt gtaaataaat ctcctaaaaa catatgactt gcataaccaa tcgtaccata
    30421 aaaagataaa ttattaatat tagtgattaa ttctatctgt tttagtaaaa aatatactat
    30481 tatagttgca aatatgctat gagaaaaact tctgtgcttt aaccagggaa aaattgacaa
    30541 cattagacaa aaaattgtaa aatatatttc aacttctatg atgtataagc atatagctaa
    30601 tagtataaat attaatgata gaaaaacttt tcttagaaat gtgtgggtta gttttgcttc
    30661 aataattata attgcaacaa atgtaattat tgcgcttaaa taaaaattat catttatatt
    30721 tattgaaata aagaaaataa taatattaac agcatatata aaaattctat atatgtattt
    30781 ggatacattg ttttttagaa tgaaatttga gaccatagaa ttagatttat ccaaatcggg
    30841 tagtacagca aaagtagctg aaactaaaat atcaactaaa gatataggaa ttttaaatat
    30901 taaagatgtt tggatagctg ttaagattcc tattgcacaa tgagttttac cacgcataaa
    30961 tcctcctaaa ttatccgata ttaaatcata taatatttag aggatatcaa aataaaatag
    31021 gtttgtcaaa ataatacgtt aaatgtattt taaatatagc ttaaaatatg atacgaatta
    31081 tggtacaata agaataactg gtagcgagtg cgtgatttga tattatttat gattgtagaa
    31141 cgtgttaaaa aattaaatag acagaaggag atgatgcaat tgttcaaaaa gaacaccaac
    31201 aagataaagg taatggcctt gggtggactt aacgaagttg gaaaaaatat gactgttgtt
    31261 gagtataaag atgaaataat tgttatagat gctggactta gttttccaga ggatgaaatg
    31321 ttaggagtag atatagttat accagatata acttatttag taaaaaatag ggataaaata
    31381 aagggtatat ttattacaca tggacatgaa gaccatatag gagctcttcc atatatatta
    31441 aagaaaataa atgtacctgt atatggggca agacttagta taggtcttat acaagtaaaa
    31501 cttaaagaac ataaaatgaa taatgttaag ttaaatgtta taggtcctag acaagttata
    31561 aagcttgata atatggaagt agagtttttg aaaaataacc atagtatacc agatgcttac
    31621 tctattgcaa tacacacaga ccaaggtata atataccaca caggagattt taagattgac
    31681 ttgactccta ttgatggaga tgttatggat atgcatagaa tctgtgagtt gagcaaaaaa
    31741 ggagttcttt taatgctggc agatagtact aatgcagaaa aaccaggatt tactatgtct
    31801 gaaaagactg ttggggtagg tcttgacgaa ttatttgcaa aaggaaatgg cagaagaatt
    31861 atagttgcta cctttgcatc caacatacac agattacaac aaataataaa tactgctgaa
    31921 aagtttaata gaaaagttgc tatatcaggt cgctcaatgg tcaatgtagt tggagttgca
    31981 aaagaattag gatacctaga tatttctgat gacatgctta tagatttaaa tgatatatgt
    32041 aagtatgaag atagtgaatt agtgataata acaactggtt cacaaggtga acctatgtca
    32101 gctcttgcta gaatggcttt ttcagagcac aaaaaagtag aaataaagag tggcgattta
    32161 gttataatat ctgctcatcc aataccagga aatgaaaaat taatatcaag agtaatcaat
    32221 ttcttatttg aaaaaggagc agaagtagta tacagtgata tagctgatat acacgtttct
    32281 ggacatgcct gtcaagaaga attaaaactt atacatgcat tagttagacc aaagtttttt
    32341 atgccagctc atggtgaata tagaatgtta aaaagacatg ctgaaatagc tgaacagctt
    32401 ggtatggaca aagaaaatat ttttgtcatg caaacaggag atgttttaga attagataaa
    32461 aattctgcta aggtagcaaa ccgtatacaa acaggaaaca tattagttga tggtctagga
    32521 gtaggcgatg taggtaatat agttttaagg gatagaaagc atttatcaga agatggtctt
    32581 atgatagttg tagttactat ttccaaggat gagggtaagg tcttagcagg tccagatata
    32641 atttccagag gattcgtata tgtaagagag tcagaagatt taatggatgg agcaaaggat
    32701 ataattaaga atgttctaaa tgaatgtgaa gagaaaaata ttaaagaatg ggcttattta
    32761 aagaataata ttaaagaaaa cctaaaagaa tatttatatc aaaaaactaa acgaaatcca
    32821 atgatacttc ctatcataat ggaagtataa tataaaaaaa ctataaattt gaaaattaga
    32881 cctcttgtaa tttttaaagt aatatcaaaa atccaattga tattatctta agaattacaa
    32941 gaggtctttt taatactcat tttaaaaaaa aatatattac ataaaatacc aattataaca
    33001 atcttttatt agtaaaaact aattatatat aaattttact gataggagga ttcttatgga
    33061 tgatgtttca agacaaaatg ctataaaagc tttaaaacaa acaaaaatgg aaatagcagg
    33121 agagtatgga atgaattatg aagatgcttt tgaaataata gaaaatgcgt ctaataaagg
    33181 tgttttagaa ggttacttta aaaagcttga aaagaaaaaa aatttaggtc aaggtatatc
    33241 taggcattta gaataaaaaa agttaaatgt gagaaaataa gtttaaataa actttaagag
    33301 gtgacatcga tgaaaaaatt agctagtact gctttggcta tattaattgc gcttactcct
    33361 ttaagctttt cttttgcaaa taataaggaa aatgctgatg ccaaccaact aaatatatct
    33421 tcaaaatcag caattttgat ggatgttggt agtggacaaa ttttatatga aaaggatgct
    33481 cataaaaagc ttcctcctgc tagtgtaact aaggtaatga ctatgctact tatagtagaa
    33541 gctttggatt caggcaagat taagcttgat gatgaagttc aagtaagtga aactgcatct
    33601 agtatgggtg gtagtcaaat attcctagag ccaggagaaa ctcaaaaggt tgatacatta
    33661 ttaaaaggta tagctgttgc ttctgcaaat gatgcttgtg ttgctatggc tgaacactta
    33721 gctggaagtg ttgaaggatt tgttgataga atgaatgcta aagcaaaaga gttaaatatg
    33781 aatgatactc attttgcaaa tacaaatgga cttccagttg caaaccacta tacatctgct
    33841 catgatatag ctttaatgtc tagagaacta ttaaaacacg aaatgataag taaatactta
    33901 actacatgga tggataaggt tgtagtaggg aagaaacaag ttacagtagg tcttgcaaat
    33961 actaataaac ttataaagca ttatcaagga gcaactggtg ttaaaactgg ttttactcaa
    34021 gaagcaaaat actgtttatc agcatctgca aagagaggta atactcatct agttgctgca
    34081 actttaggag cagagacttc tccagaaaga tttaatgatg cctctagcct tttaaactat
    34141 ggatttgcta attatgaaag tgttaagtta tgtagtaaag gtgataatat agcaacactt
    34201 acattggata aggctgatga aaacaaagtt aaattggttg ctaaagaaga tttaaatact
    34261 cttattaaaa aaggaagttc taaagaattt gagaagaaaa ttgaaatagt aaaaaatcct
    34321 aagatgccaa ttaaaaaggg aactgtttta ggaaaaataa agatatgtaa agataaaaaa
    34381 gtaataggcg aagtggaatt gataaatact aaggatataa ataaggcaag ctatctacaa
    34441 atgcttcaaa gaataattga taatatgata taaataatta tcagatgaaa tataattata
    34501 atacacaaag atatgattat aatacacata aaaaataccc ttatgtaatt atttgccata
    34561 ggggtatttt tatttaccat atagaagtat tttataatct tatgattttt atagaaatat
    34621 agaaaagttt atgtatctta aaatatcatt tgatttaata tcatatatag ggttgtttaa
    34681 caattatcta agtaaaggca tactaccagt aagtttattc actttctttt tattcccata
    34741 aattgctatc ccaaaatact gtaactcatc ttctggaaca ctagcaatct tttgtgtaaa
    34801 ttcttcataa agattgcaac tttgtgctac atctgaaaaa tctacaacag ttaaatcgtt
    34861 aaattccaaa gtatataatt ttttacgtaa atcttttatt atttctttgt ttccttttaa
    34921 aataggtaca ggaatgtcaa taattcctaa gtggctatta cctgttttgt caattacatc
    34981 tgggccaaca gtttctgggg catgttttcc tagtgtaatt cccattatag ctgctgtatt
    35041 ggatataatt cccattggta aattttcgtc tattaccatg acacattttg aatttttatt
    35101 ttccattttt atttctcctt tttaccttat ttaaagttgt ttgaatcatc atttataaat
    35161 atattttgat actgctttgg tgtaagacca ataaaattct taaaaaagtt tgtaaagtga
    35221 ctttggtcta caaatcctgt ttgtatcgca gcatctatag gttctacgcc tttttctaaa
    35281 agctttttag ctttgtttac ccgtatattt tctaggtatc tatatggtgt aatacctttt
    35341 aatttcgtaa aattacgaag tagagagtac ttattcatac ctgctatagt gcttaattcg
    35401 tcaagtacta tatgttcagc ataattattt tctagataat cacatactgc ttgaatttct
    35461 atatttgtat tttccaagtt agattgcaaa tttggctctg tatgttcttc aattaattgt
    35521 tcaattagga agaaaaaaag ctcttccttt ttaaaatcca attcttcttc catgattata
    35581 tagtgtaatt cttgtagtag aggtactagc tcactgcgaa atataacagg ttgattaaat
    35641 tttggtaaat aatttttacc tgtaatttca aagacggttt ttttcattat ttctggctta
    35701 atattaatac atctgtaatc aagtacttta tcatctattt gttcacaagt atgactatca
    35761 aaagggttaa aaagtagcaa atctccagta cttgtggtat actctttatt tttacaagat
    35821 aaatatcttt gacctttttc tataaaacca attacataat gttcatgaaa atggtttggg
    35881 aatttttgca ttatgccttt aaatctatat gcttcaattt ttaattccct atcaaagcat
    35941 actgtgcgtt cttcttgtct cacttaggta acctcctttc atgttataca aagtgtaaca
    36001 catatttttt tatacttctt gtataatatt gactaagaga caataatgtc aattcatgtc
    36061 aatataatat tatacttaca gtaggtgtaa ttattatatt ttcacaatga atatgatata
    36121 ataataaaag ttataaaata aaaagcaaat tttaatttta tgcctagaag ttaaaattat
    36181 tataatgtaa aataattttg attataagct atttaattgt tataataata ttaaaaattt
    36241 aatttaggag atgtacatta atgttaagta tgaatatagg agaaatagta gcaagtttag
    36301 ttggtatagc tatggcaata tcaatacatg agtttggcca tgcttattca gctcacttgt
    36361 tgggagatga tacagctaaa gcttatggta gaatgacatt aaatcctgta agacatgttg
    36421 acccaatagg tcttttggct atgtttatcc ttaagatagg gtgggcaaag ccagtaccag
    36481 taaatccaaa taactttaaa aactataaga taggaaacct gatagtttca cttgcaggcg
    36541 ttttttgtaa tgttttgact gctatactgt gtgtaattat caataagtat gtgcatatgt
    36601 acgctataaa tacaatagct ggatatgtgc ttttatatag tatgggattt gcagctttta
    36661 acttacttcc gatacctcca cttgatggat ggggagttat atctacattt gtaccatata
    36721 aatggaatga atatttgtat aaatttgaaa gtatgagtta tataatttta ttaattgctt
    36781 tatttactgg tatatatcaa ataatactat caccaatata tacagtgttg ctaaaaatag
    36841 tatatttatt tgtttaatat aataaacaga ttaaagaggg attgatatga agtataatat
    36901 acaattacaa gtctatgagg gaccattaga tttactttat gatttaataa caaagcataa
    36961 aatagatata aaggatatat ctataataga tataactaag cagtatctaa attatttgaa
    37021 aatgctagat aaaatggatt tagagataac tagtgaattt ataactatgg catcaaaact
    37081 tttagagata aagtctaaat atctgcttta taagcaaaaa gatgaagaag aagacccaag
    37141 aatagaactt atggaaaagt tagaagaata tagaaaattt aaggtagcat cacaagatat
    37201 aaaagaaaat ataacttatg ttaatgagag attttataga aataaagaag agataattat
    37261 tgatgacaat gtggatttag aagatatatc aattgaagca ataaaaaata tacttccata
    37321 catatttaaa gttaaaacat cacagataga aaatgctaat gatgagaaac tagataaaat
    37381 agtaaggaag aaaataatat ctgtagaaga aaaaatatta tatataagag atattataaa
    37441 agataagatt gaagttactt ttacaaatat tataaaatca tatgaaaatg atgaaataat
    37501 agctactttt ttatctatat tagagcttat aaaagaaaaa gaaatagtcg tagtacaaga
    37561 tatatttttt gatgatattc taataagaaa aagttcggag tgttaaaatg aaaagagaag
    37621 atataaagta tattatagaa tctgttatgt ttgcatatgg tgaaccaata agtataaaag
    37681 aattaaacta tataataaat aaagaacttt catcaaaaga aatagagatt atgttaaatt
    37741 tacttattga ggagtacaga gaacaaaata gaggtattca aataatcaag ttagagaata
    37801 agtaccaaat gtgtacaaat aaagactatg cagaatatat aaagaagatt attgaaccaa
    37861 agaaaaagaa aagtttgagc caagctacat tagaaactct tactataatt gcctacaaac
    37921 aaccaataac aaaggtagaa atagaggata taagaggagt aaaatgtgat aaggtattac
    37981 aaactttgtt tgaaaataaa cttataagag aagctggtag attgaataag atagggaaac
    38041 caataattta taaaacaaca gatgaatttt taaagttgtt gaatatagaa agtcttgaag
    38101 aattgccacc tatagaaaat tatcaagaag tggcaacaaa tgaataaaaa tataaaatca
    38161 caataattta gtatgtaatt ttaaatttta aaagatttaa aatgctctaa gttgttgtgt
    38221 ttttttgtat aaatataaaa ttataattct cttaaaataa atatggataa ttaagtataa
    38281 atagtaattt tttgatgata atataaacat ggagcttaat gaattattta attttaagta
    38341 tttaataata gctgtaattt ttattataag tgtaactatg ttgattttaa tatctcatat
    38401 aaacatctta ataatagctg atataaaaaa caaagatatt tgtttaaagc ttaatataaa
    38461 atacatgttt aatttaataa atataaatag acaactttat ccagctgaaa atagtaaaaa
    38521 taatgataaa aaagagggga tgaagaataa tatagattca agtatattat tagctgatga
    38581 ccttttgagc atttatagat tattaaaaaa gataaaaata catgaacttt attcaaatat
    38641 taattttgga actggaaata ttggcttaac atcttctgta tatgtattga taaatacttt
    38701 gtatggaaat ttatttaata tgattgatgc agaaaaaatg tatttaaatg taaatccaga
    38761 ttttacaaaa gattatgttt taggaaatat aaggatacat ataaggccaa gaataaaagc
    38821 tttatttaat attataataa tgattaataa aattatgaat aaaaataaag gaaataagga
    38881 aggtgatagt aatgagagca acaggttcga tacagagtct tatggaaaca actcttgaaa
    38941 caattaaagg ttctatagat gcaaatacta ttataggaga ccctataaaa acagatacta
    39001 cagtggttgt acctatatca aaggttacaa ttggctttgg tataggagga ggagaatact
    39061 caaaaggata tgatgataaa gatagggaaa ttgaattaaa aaatgaaaaa tcagatacga
    39121 attttgctgg aggtagcgca ggggctatat ctgtacaacc agtagcattt gtagtagttg
    39181 aaagtggaga gactagaata atgagtttag atagtaatat caatctagtg gataatatat
    39241 tatctataac tcctagagta ttggagaaaa ttcaaaatat atcacaaagt aataagaatc
    39301 aagataaaaa caatatgtaa gaataaaata tttttaaata tgtatatagt tttaagtaaa
    39361 gtagtggggt taatataaat cccactattt tgttgtgtac tttaaacatt tatatctaat
    39421 aagattttag tttaaaacaa ttta
//
LOCUS       DAEOTL010000033        38798 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEOTL010000033 DAEOTL010000000
VERSION     DAEOTL010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38798
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.033"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            54..779
                     /locus_tag="KRH82_001985"
     CDS             54..779
                     /locus_tag="KRH82_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655264.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            783..2186
                     /locus_tag="KRH82_001986"
     CDS             783..2186
                     /locus_tag="KRH82_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655265.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            2197..3021
                     /locus_tag="KRH82_001987"
     CDS             2197..3021
                     /locus_tag="KRH82_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBG8655266.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYALMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(3346..3966)
                     /locus_tag="KRH82_001988"
     CDS             complement(3346..3966)
                     /locus_tag="KRH82_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8655267.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            4231..4563
                     /locus_tag="KRH82_001989"
     CDS             4231..4563
                     /locus_tag="KRH82_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655268.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(4683..5324)
                     /gene="pcp"
                     /locus_tag="KRH82_001990"
     CDS             complement(4683..5324)
                     /gene="pcp"
                     /locus_tag="KRH82_001990"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBG8655269.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(5345..6277)
                     /locus_tag="KRH82_001991"
     CDS             complement(5345..6277)
                     /locus_tag="KRH82_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBG8655270.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(6299..6964)
                     /locus_tag="KRH82_001992"
     CDS             complement(6299..6964)
                     /locus_tag="KRH82_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBG8655271.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(7511..7987)
                     /locus_tag="KRH82_001993"
     CDS             complement(7511..7987)
                     /locus_tag="KRH82_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HBG8655272.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(7990..8394)
                     /locus_tag="KRH82_001994"
     CDS             complement(7990..8394)
                     /locus_tag="KRH82_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBG8655273.1"
                     /translation="MKIRNKATNKKKKYVRISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGGADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            complement(8369..8998)
                     /locus_tag="KRH82_001995"
     CDS             complement(8369..8998)
                     /locus_tag="KRH82_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8655274.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      9363..9406
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            9507..10475
                     /locus_tag="KRH82_001996"
     CDS             9507..10475
                     /locus_tag="KRH82_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBG8655275.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFISMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            10477..11040
                     /locus_tag="KRH82_001997"
     CDS             10477..11040
                     /locus_tag="KRH82_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBG8655276.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPI
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            11048..11737
                     /locus_tag="KRH82_001998"
     CDS             11048..11737
                     /locus_tag="KRH82_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8655277.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            11864..12592
                     /locus_tag="KRH82_001999"
     CDS             11864..12592
                     /locus_tag="KRH82_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBG8655278.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKKFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            12606..13280
                     /locus_tag="KRH82_002000"
     CDS             12606..13280
                     /locus_tag="KRH82_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBG8655279.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            13306..14142
                     /locus_tag="KRH82_002001"
     CDS             13306..14142
                     /locus_tag="KRH82_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655280.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            14158..14829
                     /locus_tag="KRH82_002002"
     CDS             14158..14829
                     /locus_tag="KRH82_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655281.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            14819..16051
                     /locus_tag="KRH82_002003"
     CDS             14819..16051
                     /locus_tag="KRH82_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655282.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            16201..16518
                     /gene="trxA"
                     /locus_tag="KRH82_002004"
     CDS             16201..16518
                     /gene="trxA"
                     /locus_tag="KRH82_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBG8655283.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            16535..17413
                     /locus_tag="KRH82_002005"
     CDS             16535..17413
                     /locus_tag="KRH82_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBG8655284.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTMMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            17683..18051
                     /locus_tag="KRH82_002006"
     CDS             17683..18051
                     /locus_tag="KRH82_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8655285.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            18054..18425
                     /locus_tag="KRH82_002007"
     CDS             18054..18425
                     /locus_tag="KRH82_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBG8655286.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(18569..19024)
                     /locus_tag="KRH82_002008"
     CDS             complement(18569..19024)
                     /locus_tag="KRH82_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655287.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(19063..20328)
                     /locus_tag="KRH82_002009"
     CDS             complement(19063..20328)
                     /locus_tag="KRH82_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBG8655288.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            20798..22249
                     /locus_tag="KRH82_002010"
     CDS             20798..22249
                     /locus_tag="KRH82_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBG8655289.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(22469..22930)
                     /locus_tag="KRH82_002011"
     CDS             complement(22469..22930)
                     /locus_tag="KRH82_002011"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBG8655290.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(23035..24228)
                     /locus_tag="KRH82_002012"
     CDS             complement(23035..24228)
                     /locus_tag="KRH82_002012"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBG8655291.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(24251..24916)
                     /locus_tag="KRH82_002013"
     CDS             complement(24251..24916)
                     /locus_tag="KRH82_002013"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBG8655292.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(24950..26062)
                     /gene="ribD"
                     /locus_tag="KRH82_002014"
     CDS             complement(24950..26062)
                     /gene="ribD"
                     /locus_tag="KRH82_002014"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBG8655293.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(26194..26315)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            26504..28987
                     /gene="recQ"
                     /locus_tag="KRH82_002015"
     CDS             26504..28987
                     /gene="recQ"
                     /locus_tag="KRH82_002015"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBG8655294.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAAIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      29076..29187
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            29329..30630
                     /gene="thiC"
                     /locus_tag="KRH82_002016"
     CDS             29329..30630
                     /gene="thiC"
                     /locus_tag="KRH82_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBG8655295.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            30684..30878
                     /gene="thiS"
                     /locus_tag="KRH82_002017"
     CDS             30684..30878
                     /gene="thiS"
                     /locus_tag="KRH82_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBG8655296.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            30871..31674
                     /gene="thiF"
                     /locus_tag="KRH82_002018"
     CDS             30871..31674
                     /gene="thiF"
                     /locus_tag="KRH82_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBG8655297.1"
                     /translation="MVKIKIFVNELLTDVEENITAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            31737..32507
                     /locus_tag="KRH82_002019"
     CDS             31737..32507
                     /locus_tag="KRH82_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBG8655298.1"
                     /translation="MDKLILGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            32524..33627
                     /gene="thiH"
                     /locus_tag="KRH82_002020"
     CDS             32524..33627
                     /gene="thiH"
                     /locus_tag="KRH82_002020"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBG8655299.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            33628..34317
                     /locus_tag="KRH82_002021"
     CDS             33628..34317
                     /locus_tag="KRH82_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBG8655300.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKEFRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            34505..35899
                     /gene="yfcC"
                     /locus_tag="KRH82_002022"
     CDS             34505..35899
                     /gene="yfcC"
                     /locus_tag="KRH82_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBG8655301.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            36416..37783
                     /locus_tag="KRH82_002023"
     CDS             36416..37783
                     /locus_tag="KRH82_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBG8655302.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            37808..38416
                     /locus_tag="KRH82_002024"
     CDS             37808..38416
                     /locus_tag="KRH82_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBG8655303.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            38464..>38798
                     /locus_tag="KRH82_002025"
     CDS             38464..>38798
                     /locus_tag="KRH82_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBG8655304.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNI"
BASE COUNT        14834 a         4393 c         6267 g        13304 t
ORIGIN      
        1 ttttagataa aatatatgct aatatatatg taaattatta caggaggttg tttatggaaa
       61 atcgtgtttt aataatagat gatgaagtag aaatattgaa gcttttagaa actgtcctaa
      121 aaaaagaagg ccttaataat atatatactg caaaaactaa aaaagaagga ttagaattat
      181 ttaaaagtat taatcctgat ttgattgtat tggatattat gttaccagat ggcgaaggtt
      241 atgatatttg taaagaaata agaaaaacct ccaattctcc aataatattt ttatcagcta
      301 aaaccgaaga attagataag ttacttggac tagcgattgg aggagatgat tatgttacaa
      361 aaccttttag ccctaaggaa gtggctttta gagttaaagc gcatttgaga agattaagtt
      421 attttagtga tgctcaaaac gaaagtaaaa atctaaataa taatgaagaa aaaattatat
      481 catttggccc atatatatta aatgaaagta gggcagaact tataaaagat ggaaaatcta
      541 taggactgtc tgcaaaggaa ctaaaaatcc tatctttatt tgcacataat caaaatcaaa
      601 ttataagtaa agaaaaacta tgggataaag tgtggggaga agattatgtt ggatttgaca
      661 atactataat ggttcatata agaaaaatta gggaaaaatt agaggataat ccttcaaaac
      721 ctgaatatat tctgacaata aaaggtcttg gatataaatt agcagtaaag gaagattaga
      781 atatgaagtg gaagattact agaaatttta tatttacaat tgtgtttgta gctatatcag
      841 tagtaattat aaatatcata tctatattgt atgtgatttc aactaatagc ttttttaaag
      901 ttgtagattc tggaaataat cctgaagaat ttgcacgttc ttttgaaaaa gatttatatg
      961 aaaaagatgg agaatttaaa ctatctaaga ttggagctga aaaattagaa aaatcaaatt
     1021 cctggataca ggttttaaat gatttaggag aggaagttta tggagtaaat gtgccaaagg
     1081 atactccaaa aaaatataca ccctttcaaa tggtgaataa ttacaagtat atagaaacaa
     1141 agtatgttaa ttttgtacta gaaaaatatt taaacaaaaa acatctaaac ataatagtag
     1201 gtatacctag tagagatata tcaagaataa ttttaaccta ttctcaaaat aacattaaaa
     1261 aaactttaaa taaagttatc attataacac tagtaattga tagcgtggta gctttaggcg
     1321 taggatattt atttagtaga aaacttacaa aaccaatttc aagcgtacta tggagtattg
     1381 agactatggc taatggaaat tatagtttat atcttaagga cagaggtata tatgaagaag
     1441 tttttaaaaa tataaatatg ttagctgata ctttaagagt aaatgaagtt gagagaaaag
     1501 aaaatgaaga gttgagagag gaatggctgg caaatataac acatgatata aagacacctc
     1561 tagcatctat acaagggtat gcagagataa ttaatgacaa agattatgag tttgaagaag
     1621 atgaaataca agagtataca gaaattatat ataataagtc taagtatata aaagatttag
     1681 ttgatgattt aaatttatct actcgattaa aaaataatac tatagttctg gacaagaaaa
     1741 aaataaattt agtcagttta gtcagagata taataattga tattttaaat gataatagat
     1801 ataaaaatag gaatattgaa tttgaaagta atgaagattt aattgaagta tatgtagatt
     1861 caatcttatt cagaagggct ataaccaatc ttatatttaa ttcaatagtt cataatagcg
     1921 aaggaacttt gataagtgta gaaattgtaa aaaaagataa tatagaaatt ataataaaag
     1981 ataatggaat tggaataagc aaaagtgatt tgaaacatat ttttaaaaaa tattatagag
     2041 gtactaatac aggtgagatg cataaaggtt caggtcttgg tatggctatt tctaaagaaa
     2101 taatagagat tcataaaggt aaaatttatg taagtagtga aattggaata ggaacaaaaa
     2161 ttattataga gataaaacaa aattaggaga tatgatatgg atttttttaa aaaaggtata
     2221 agtgggttta ctattaagat tttagcatta atatttatga catttgacca tatagcagca
     2281 tttatgccac aaacaatgca aataccaatt tggtttcatt gggtaggcag aatatcagca
     2341 ccactgttta tatttatggc tgttgaagga ttttatcaca ctagtaacag aaaaaaatat
     2401 ataagtagat tgtatatttg gtctgttatt atggctatag gaaatcaaat aattaataat
     2461 gtattttcac atccagaagg agctataatt ataaataaca ttttttcaac attattttta
     2521 atagcgattt atttacaagc aatagagttc ataaagaaat ttagaaaaga gaaagaaatt
     2581 aaatatttta ttataggatt attgatgata atcattccta taattttagg aatatttaca
     2641 gtagctttac tttttaaagt cactaacaga gttattgctt tatttatgat tttggtacca
     2701 gtaccatttt tagtagaagg tggaccaatt tggattatac ttgggattat tttttatttg
     2761 tgtagaggga aaaagttcag tttgagtatt tgttatgctt taatgtgtat atttatattt
     2821 acaacaatgt caaatggaga ttatagttta aaaaattcta ttttacaaaa ttaccaatgg
     2881 atgatgattg cttctctacc tttaatgtta ctttacaatg gagaaaaagg gaagagtatg
     2941 aagtatttat tttatttata ctatccaatc catgtatata tattgtatat cttaggaata
     3001 tacttaataa atggtttttg attgtaagtg atatttttaa tacaaaatga acaatatgag
     3061 gattgtttta ggtctattaa aattgttatt tagatgagat ttgtagaata tttaaattta
     3121 tgagcagaaa ttcagttatt gtaatttcaa taacattaga atataatatt ataatttatt
     3181 tagaaatata tgatgttata catggtttgg ttattaatgt aataataaaa cagaggtttg
     3241 atataaaatt caatacctct gttttagtgc tttttatcct acatttatgc ttattttatt
     3301 tataaattag tgttttgttt taattaatat tagtacattt tttatttatt ttataaaatt
     3361 agtcataatt gtttcttcat attgtggttc tttaattcca gcttttttac ctgctgatat
     3421 acacttaaga agccatgcca tgttttctcc tagagttcgc atagtctgta atccttcttc
     3481 atccttcata acatcctctg gagtaaagcc atgtacctgg ttccaatact gtgatgatac
     3541 aataggcata ttgctgattg aaaaatattt atttagttgg tcaaatgttg cacttgcacc
     3601 accacgtcta catgacacaa ctgaagcacc taattttgta gccatgcgac ttccagctat
     3661 gaaaaataga cggtcaagaa aagaagttaa ttgaccagtt gcactagaaa agtaaacagg
     3721 agaaccaata ataataccat caatattatc cagatcttca atcaattcat taactttatc
     3781 atttcgaatg cattttccag tttcaaaaca ggatgcgcaa ctaatacatc ctgggattgt
     3841 ttctttacct aaatacagta tttctgtttt aatatcgtgt ttactcaata ctttagtaat
     3901 ctcatttagt gctgtataag tacatccata ttggtttggg ctaccgttta tcaataaaac
     3961 tttcattata aatttcctcc aatgaatttt atttaataga ttttctaaga gatattattt
     4021 tttataaaat aggattttca tgaatattat caatttatat agaaatgtct aatcttagaa
     4081 tcctatttaa aataactttt ttttagtaaa tacacctcct attataaaat tgactttcaa
     4141 ttattcttac actataattt tattataaat tattctaaaa acaagtacgc acatttttgt
     4201 tcaatactaa ccaaaaggag agtgtaatat atgagtatag actgtatatc aaatacagat
     4261 ttaagtgaaa caggatttag ttatacactt tcactgatta gtggtaaata taagatgata
     4321 attctttact gtcttgtaga atttgaagtt gtaagatata atgcattaaa acgttatata
     4381 aatactatct cctataaaac tttgagttta tcattaaaag aattagaagc agataacttg
     4441 attattcgta ctgaatatcc tcaaatacct cctaaggtag aatatagtct atcagaaagg
     4501 ggaaaatctc tgattccaat tttagatgca atgtgtgagt ggggagagag gaatagacct
     4561 taattttgta tctgtagata ccataaaaag actgtgagta aaattgtttg aataatctac
     4621 tcacagtcta tatttaaatt aatagttagt atttttaatt tataaaaata ctaaaaaatt
     4681 tattatgaaa tttcaccacc aatttctttt acatcttctt tatatataat acaagcttct
     4741 atagctaatt ctaagccttt tactatttct tctaaagaca tgaatggtgt atttttttta
     4801 tctattactt gtgaagttgt atatgggatg tgtataaatc caccccttat attaggatat
     4861 ttcttgtcta tcatataaag aattccatac atcacatgat tgcaaacaaa tgttcctgca
     4921 gtgtttgaaa cactagctgg aattttattt tcattcatat gttttaccat agcttttaca
     4981 ggcaattttg aaaaatatgc aggttcacca tcttctttta taatagtatc tataacctgg
     5041 ttaccctcat tatcttttat tctaaaatca tctatattta tagcaactct ctcaggtgta
     5101 atgtcaaatc tacctccagc ttgtccaact gatattacta tatctggatt gtgctcttga
     5161 atagctttat ctatagcttc aacagatttt gtcataactg ttggtatagt tatctttatg
     5221 atttctgcac cgtttatatt attattgacc ctttcaactg cttcttgagc tgggtttatt
     5281 ggttctccgc caaatgggtc aaatcctgtt aacaaaattt tcattatttt acctcctaat
     5341 tatattaaaa tcctaaaaag tacattacta atatgtgggc tataattaat accaaagcaa
     5401 ctggagcttg atattttata acaatataat catttttaca ttctagcaag gctgctggaa
     5461 ctatattaaa attagcagcc attggagtaa gtagagttcc acaatatcct gctgttaatg
     5521 ctaatgctcc aattatagca ggatttccac cttgagacaa tacaaaagga ataccaattc
     5581 ctgccgttat gactgaaaat gcggcaaatg catttcccat tatcatggta aatataacca
     5641 tacctaatac ataagctata acaccaaata atctgctatc agcagggact acaccagata
     5701 tcatggttga aataacttca ccgactccgg cttgagtaaa taaagctccc aatgcaacta
     5761 aaagttgtgg taacatacta gcaggtccca tttgttgaag taatcttgag ccatcttgaa
     5821 ctgatgtagc aggttttgcc ttagttatta taagggctga tattaatgca attattgaac
     5881 ccacacctat tgcaaattga gaagaattat caaaattaga aaggctcata gctactacta
     5941 ctgcagcaaa tgctaatatt aatgatggta taaatatttt atttttaagt ttgtctgctt
     6001 gttcttttcc aaaattttca tctggttctt catactttgc aaatacaact tgtttagaaa
     6061 gtgttaataa actagataat attaatatta ttcctattat attggctgga atcaatctac
     6121 caaatatgaa tggcaatgat ataagtatcc aaaataatga tgtaccatat ttcttattgt
     6181 tatttatggt agtaaaagac ttatatgcta taacaatcat taaaaatccc attagtgcgt
     6241 aaaagatttc taatgatatg tttataaaat tttgcatttt tattcctcct aaataaaact
     6301 attttttatg acttttgttt aattttttat catataaggt aaactggatt gtagccacta
     6361 caagtgctat tactgccata atagtactag cctttacaat attaagtcca gttacattgt
     6421 atccaaattg agtcagagta gatgctataa gtaatactcc actactacct gcaaataagt
     6481 tttgaccata aaaatttcca tagttttctg atgcagcaga taatgccttt atggcttctt
     6541 catccgattc ttttagttca tcactattac ttaaaccagc agcttgtgcc ataggattaa
     6601 caagtggtct tacaaattga ggatgtccac tcattcttat tgatagagca ccagctattt
     6661 gtctagctat catgtatata gtaagtactt ttcctgttgt aagtcttttt aatttttcta
     6721 ttaaagaaac agctctttgt tttaaaccat atctttctaa tacaccgatt actggcaatg
     6781 ttaatatgaa taatgataca cctctgtttg agacaaaaga atctcctaaa attgtaaaaa
     6841 tttgattaaa atctaatcct gcaacaattc ctgttgccac tcctgctaat aatacagtaa
     6901 atagtgtgtc aattttaagt ataaatccaa ttacaactat caatataccg attagtttta
     6961 tcataaattg ttctccttcc atttctatat gttttaattt aaatttattt aatggataaa
     7021 gttaaactct ttttatagta tttgcgttaa taggactatt attataaaat ttaataaaaa
     7081 atagggaaga tgtttttaag tatcaaagta aataatggtt gtgtatagga atttgaataa
     7141 caaagattat attttaagct aatatgaatt gattttgtaa gtctatagtt taagtatatg
     7201 tcaatatttg aaataggttt taaattagat attatattat aaaaagagaa tgtgccaaac
     7261 atagagacaa gtgtattttt cacttttgaa atgataaaaa tatatttgat ttcatacaaa
     7321 aagagagtgt ctaatgaatt ttttagttca ttagacactc tctttttgtt atgattaata
     7381 aagcatatat taagtgctag tttcattaga tttcactaag aaaaataaaa ttttgataaa
     7441 gtttaaagac tattttgagc aatattactt ataaataaaa gaatttatca tagagataat
     7501 tagttttatt ttagctatta agatttatta aaaaattatc tatattatcc tgtgatattc
     7561 taaaactgtc ataattacct tttgaaacag ccttcataat aagtttatct aaaaatttca
     7621 ttttttctaa tcgagcttca ctaccaaaaa ttccaatagc atttgcactt tctaataagg
     7681 atgatggaaa atttgatttt aaatatttat ctgcttgttc agaaaagcca cagcaaagga
     7741 aaatgccaac ttgttttttg tttaataact ctacattatc attacatagc acttgtattt
     7801 tttttgaaac tgaaccaaca tatatagaac ttccaataat aattttatca aattttgata
     7861 actcaatttt attattatta ttattaatat caacaatagt gacattatct gatagtttat
     7921 tttttagtat atttgcacag tcttttgtac aaccatattt acttgaatat ataataatag
     7981 tattcataat tattctccct ttcttaaagc attttctaca gcttttcgta tagtattact
     8041 gctataagtt gcagaagtta tagcatccac atctaaagac tgttgtttaa taatacttgt
     8101 tgtaattttt tcagcaggtt tacctaaaag atggtcgtgt tttaagatat taatattttg
     8161 gattttacca ttattaactt caacagacac agtagctttt accaagttat tatcagcacc
     8221 tccagtataa atgccatttt taacattatt aatatctata tcttttacta ccaagttttc
     8281 cggctttaag ttgcttacaa ttacaataat aatgcatata aatacaaaga atagagcaat
     8341 agatattctt acatattttt tctttttatt agtagccttg ttgcgaattt tcattgtaaa
     8401 gtcctcccac taaaatatct aagaaatttt ctataagttg agaaaaatta tgtaaagaat
     8461 atagtttatt ttcaacaaca cataaaacga atcctaacaa tgcacttata agcatccatg
     8521 agcttttatc tatatttttt ttgaatattc cttgttcaat tccaatggaa aggaatttat
     8581 caagcatttt tataccatta ttgctaggcg tattgtttgt attttcagat gcaaatataa
     8641 tattcattct actatgcatg atagattttg ccatctctgg ttcactagaa agagttttta
     8701 taaagctagt cataatttct atgatttgtt tatctattgg tagtgatgag caattattca
     8761 taatgtcaat ggcattactt tctactgtgt tataaagttt attggtcata tcgctgataa
     8821 tttctgcttt gtctttgtag taaagataaa ttgtagttgg agaatattct atttttgtag
     8881 caatttttct tattgataaa ttttcatatc catgttggtt tataatttcg atgctagcat
     8941 ccataatctt tttcttcatt tcttcttttt catttttacg tctttctttg atactcatat
     9001 aattacctct ttgcttaacg gtgttaagtt aatttacact gttattgtat aatttaattt
     9061 taatactgtc aataaattat taaataatat aagttaatat atttttatgg ataataaatt
     9121 aatgttatta attgtaatat ttaagatatt attgtataat aataatcggt ttaaatgcgc
     9181 cacatcttat taaagttggt tcataattct aaataaactt taataagata cactaaaata
     9241 taataaattc ttttatgcta taaaatttat tttatagcta ttaaatcaga tgtttaaaaa
     9301 ttttttaacg gtctatagtt tttaagagtc tatagtaagt agactaaaaa tatgatttta
     9361 catctgtact tgttcgagaa ctccaagtat aaaaaactaa ggaattatat agtggcagta
     9421 tataattaat acccttagac acaccttttt gaaagtggaa aaaagatgtg tagttctcct
     9481 cgaccacaaa tcaaggagga taaaaaatgg aaaagagaaa agtaataatt gattgtgacc
     9541 caggaattga tgattctttg gcaattcttc tggctttaaa ctcaccagag ctagaagtga
     9601 ttggaattac cacatgttgt ggaaatgttc cagcaaatat aggtgcagaa aatgcactaa
     9661 aaacacttca aatgtgttct tcactaaata ttccagtata tataggagaa gaagcaccac
     9721 taaaaagaaa acttgtaaca gctcaagata cacatggaga agatggtatt ggagaaaact
     9781 tttatcaaaa ggttgtggga gctaaagcaa aaaatggagc agtggatttt ataataaata
     9841 ctttacataa tcatgaaaaa gtatcaataa tagcacttgc accacttaca aacatagcta
     9901 aagcacttat taaagataag aaagcatttg aaaatctcga tgagtttata tctatgggag
     9961 gagcatttag gattcatgga aattgctctc cagtagcaga gtttaattat tgggtagacc
    10021 cacatggagc agattatgtt tacaagaatt tatctaaaaa aatccacatg gtaggtttag
    10081 atgtaactag aaaaattgta cttactccta atattattga gtttataaat agacttgata
    10141 agaagatggc aaagtatata actgaaataa ctagatttta tattgatttc cattgggaac
    10201 aggagggaat aattggctgt gtgataaatg accctctagc agtagcatac tttatagata
    10261 gaagtatatg taaaggattt gaatcatatg tagaagttgt agaagatgga atagctatgg
    10321 gtcagtctat agtggattct ttcaatttct ataaaaaaaa tcctaatgca attgttctaa
    10381 atgaagttga tgagaagaaa tttatgtaca tgtttttaaa gaggcttttt aaaggttatg
    10441 aagacattat agactctgtg gaaggagtga tatagtgtga aaagaaaaat atgtgtaaaa
    10501 actattacac ttatagcttt tggtatttct ataaatataa taggcgcttt tatagctatg
    10561 ggattaagat tacctgtata cttagattca ataggaacta taatgatagc ttcactttta
    10621 ggacctaaat acgctgttgt tacaggtgtg tttggaagtt taataagtgg aattacgttt
    10681 gatgtgtatt ctctctattt tgcaccagtt caaatatcaa ccggattact tgctggaata
    10741 gcatttaaaa agaatttttt aagaggttta aaaactccaa taggagtact tttatttgcc
    10801 attccaacat ctataataag ttcaataatt tcagcatttt tatttggagg tatgacctct
    10861 tctggttcat catatatagt gcaaatcttg aaagtgttag gactgggaga tgtttttagt
    10921 gtgtttgtaa cccaagtatt tactgattat ggagataagc tgttagcagt tgttttagtg
    10981 aatttaggat taaatgcagt tccaaaaact ttaaaggtat cattgactgg aggaaaatag
    11041 atagaaaatg gatagatata gtgagataac aaataaaaat caaagagaaa ttgttctgct
    11101 taaaggattt ccttgtatat ggggaaagtg ttctttttgt gattatatag atgataattc
    11161 taatttagaa gaagagatga ataaattaaa tctaaaggtt ttaaaaaacg taactgggaa
    11221 atatggagtt cttgaagtca taaattctgg aagctgtttt gaattaccta aggatacttt
    11281 agaaaaaata aagtgtatta taaaagagaa aaatataaaa aaattatttt tagaaagtca
    11341 ttggtcttac aaaaataggc ttaaggaaat gagagagtat tttgaaattc ctgtggtatt
    11401 taaaattgga gttgaaacct ttgacaatga ttttagaaat aatattttaa ataaaaatgc
    11461 aaattttaag actccacaag atgtaaaaga atattttgat tcaccttgta ttatggttgg
    11521 aataaaagga caaacaaaag agatgataga taaagatata gagattatcc taaatacttt
    11581 tgaaaaagcg acagtgaatg tttttataaa taattcttct agtataaaaa gagatgaaga
    11641 gttagtgaaa tggtttgtta gtaagtataa attcttggat gaaaatccaa atatagaagt
    11701 tttatacaat aatacagact ttggtgtagg agattagcat taatttagtt taaatttaaa
    11761 attgaaaagt ttcttatgtt tttgaaaaag cttctaatag ttagaagctt tttttgtaga
    11821 gttttatgtt acaataagaa aaaaggaatt aaggagcaat taaatgatgt ttgatagggg
    11881 aaaatggaat aaattggatt ataatgaact tttagaatat atgatgtcta tacaagatat
    11941 aaaatataga gattttaata aaaagcttat acctggaaca gaaaatataa taggtattag
    12001 agttcctaat ttaagaaagt tatcaaaaga aataagccaa ggaaattgga agaaattttt
    12061 agaagtagca gaggatacat actatgaaga agttaggcta caaggtatgg taattggcaa
    12121 tataaatagt aattttgaag aaactttata ctatgtaaaa agatttatac ctaaaatcga
    12181 taattggtca gtttgcgatg gattttgttc tgatttaaag tctatgaaaa aatataaaga
    12241 aaatatgtat gatatactta aaaaatatgt ttattcaaag aatccatggg aaattagatt
    12301 tgcattagtt atgtttttaa tatattatgt tgatgataaa catattaaag aaatatttga
    12361 atactgtaat aatatacaaa gtgaagaata ttatgttaaa atgggtatgg catggttgct
    12421 atcaatttgt tttattaaat gtgaagagga aacttttctc tatataaaaa ataataattt
    12481 agatgatttc acttataata aaatgctaca aaaaataatt gaatcaaata gagtagattt
    12541 agaaaagaag aatataataa gaagtatgaa aagaaagaca agaagatgtt gacggaggaa
    12601 tattaatgaa taacaatgaa gacagaattg acaaattttt agaacttcaa agcaaaggat
    12661 ttaaatttgc agagatagct caaaatctaa agattagtca aagtacttta agaacttttt
    12721 taaataaaaa aggatataag tcagaaaaag gtaaatacat attaaaagac gaattaaatt
    12781 ataataaaag tttggataat agaaacttgg aagaagagaa agctaaggag tatgaaaaaa
    12841 gtaaaaagaa tactataagt aatagaaaaa aagtaagcac caaaaaaaag atttctaatg
    12901 aaaaggcttt aagtaaaagt gttgaacaaa ttgagtttaa tgatacaggc ttaaaaaatg
    12961 caaagccaaa acaaaatatt aagcctaaga aagatagaaa aataaatata actcaagaag
    13021 atttagataa gctttgtgaa gtatatgatt ggtatttaga agtaaaagat tacaatataa
    13081 agcctaaaaa agtatctaat aaaaaagatg tacatataga tgatgaacac atagatgaat
    13141 taaaaacaac aagaatacgt atagataaag aaatatggaa tgattttgaa agattatgta
    13201 gtaattcgaa ttttgaaaaa catcaaatac ttacacaggc attgaaagaa tttatgaaaa
    13261 agtataaaaa tctactataa aatactacta tatgaggtgc ttaatatgaa taaaatagta
    13321 aaaaaatcaa tttctctaat gattatatta acaatattta tttttatgtt gacagcatgt
    13381 gaaaaagatg aacagcctga ttcagttgat attcaaacag aagataaaaa tgagataaaa
    13441 atagatgagg gaaatgcaaa agtattgaat ataggaaaat cagaaattat aaatatagat
    13501 gaaggtgata aagtagatac atcaacaaag gtagaaaata attcaacatt taatatatcc
    13561 aatgttgaat tgatatataa tgaatatgat gagaataaaa aaattatatc ttcggatagt
    13621 aaggctttgt tggacatgac tttaatgcct gggaaagttg cttacataga atgtgggcat
    13681 aaaacttttg taaagggtgt agaagtttat gcatatgaat atgaggcaga gggtaagatt
    13741 gtgtatgtta atttaaaaga aaatactatt aatataagaa ataataatat taagctagaa
    13801 aatagtagtc agtatgaggt gctatctaca tcagaactta aaaaagtaaa tgaatcaaat
    13861 gagggaatta cgtatcaagt aaaagtaaaa aattcatcat caaaagattt aggaaatatt
    13921 attcttaaga cagcagaagt taatgaaaat ggagaatatt taacagtaaa tcgtgtgcca
    13981 tcatataaga ttttaaagcc ttcagaagag acagatatag atatattgtg ttcaacaaag
    14041 gcaaaaagtg ttgaaatagt gggatatacg tatgatgata taaaagaaaa agccaatgtg
    14101 gatattgact taaaatctca taaagttaag atagacaaat aaaggtaggg gatacttatg
    14161 aaggttttaa tagttgaaga taataagata cttttagaaa gtgtagtaga agaacttagc
    14221 aagcattttg aaactgaaaa gtgtgaagat ggagaagaag ctttatactt agtaaatcaa
    14281 aatatatatg atttagtcat tttagactta atgcttccta atataaatgg atttgatatc
    14341 ctaaagaaaa tgagagttaa taatatagat acacctgtac ttatattgac agcaaaagaa
    14401 acattagatg acaaagtaga agcatttact ataggagcta atgattattt gacaaaacct
    14461 ttttatatgg aagagttagt agctagggta tacgctatat taaggactaa tggaaaaata
    14521 aaagaaagaa acggattaga atttaaatct ttatatttag atacactaga aaaaagagtg
    14581 tatattgaaa aagaagaaat aaaacttcaa aacaaacagt ttaacttgct tgagtatttt
    14641 gtattaaata aaggttcaat tttattaaaa gagcagattt atgatagaat atggggaatt
    14701 gattcagatg cgactattga aatagtggaa gtatatgtaa gtaatctaag aaaaaaacta
    14761 agtaaatatg gatatgataa atatattaaa actaaacgta aggtaggata tatattcgat
    14821 gataaataag aatgtattta ccagtactaa aaatcattta ataaaaatgt atattattgt
    14881 agtaggtagt tttttaataa tcttttctat atttatatac tcatatttta ggggacttac
    14941 atatagtgga attgatagtg agataaatga tgaacttgaa tatatagtct ctcaatttaa
    15001 aagaacttca tttttgaacc caataagact gaaagatcct aaagatatgg tgtatgtata
    15061 tgaagatgga aggataagtt actatactca aaatgaatat tttgatgagt tacttccaga
    15121 tagaagacta gataaaaaaa attcgttttt taaatacaca gaaaatggat atacttttag
    15181 agaattaaat gtagatgtag gtagatacca aatacagata attagaaata tagattctga
    15241 gatgaattct ttaagacagc ttacatctgt tcttataatt ggaatattaa tttctgtaat
    15301 aattacttac tttgtggctg tatatctcac tagaaaagct ttaattccaa tagaaacagc
    15361 atggaaaaat caagctaagt ttatacaaga tgcttctcat gaattaagaa caccaataac
    15421 aatagtttca tcaaaattag aaagtatgtt aaaatcccca gaaagtacag taaatgatga
    15481 agttgaaaca atagctactg caatgaagga aactagaaga cttaaaaaaa tgataactga
    15541 tttattgtct cttactaaag aggactctat tgttaaagtt aatttagaag aaatagattt
    15601 agaaaagtta ttggaagaaa tatcagaaga ctatattgac attgctgagt ttcaggaaaa
    15661 aagattcgtg tttaattcta aactgaagaa taaagttata ataacagata aaaataaatt
    15721 aagacaactt atattaattt tcattgataa tgcctttaag tatacaaaat tgggtgatga
    15781 gatagcatta gaattgaaag aagatataga ggatgaggta actttactta taagtgatac
    15841 tggtataggc ataaaaaaag aagagatacc tcttatattt gatagatttt ttagaagtga
    15901 aaatgtaaga aataaagatt tagaaggttc tggaatagga ctttcaatag ctcgcatgat
    15961 tagtttaaac ttatctattg atataaatgt aacttctgat gtagatattg gaactacatt
    16021 tgaattgtca ataccaaaaa agttaaaata ataaaaatat aaaaaattgt ttttagaaat
    16081 gaagaatggg tatactaatt agtataaaat ataaaaagac cttataaaag taaatttata
    16141 tttataaatt tcatagtata attatatagg gataataaag tttaatagga ggatttaaaa
    16201 atggcaaaag ttataaatac atctgaattt agaagtagtg ttgaaggtag taagggagta
    16261 gttgtagttg atttctttgc aacttggtgt ggaccttgta acatgttggg acctgtattt
    16321 gcagaattag gtgaagagat gaaggataaa gctagatttg taaaagttga tatagatgag
    16381 agcttagaaa tagctcaaca attcaatgta tctacagtac caactatgat tatatttaaa
    16441 gatggaaaac cagtagaaac tttaattgga ttcatgccaa agaacaaaat tgaaatgcaa
    16501 gtaaaatcat atttataaaa aatgggtgag tattatgaga tatgatatag ctataatcgg
    16561 cagtggtcca gctggattgt ctgctgctat aaatgcaaaa ataagaaata aaacaattat
    16621 catgtttggt aatgataatt taagtaataa gcttgttaaa gctccttcaa tagataatta
    16681 tttaggtttt tatgatataa gtggtgatga attaaaagac aagtttaaat cacatataga
    16741 tagtatggat atttcaattg aaaataaaag aataaataat atttatgcta tgggagaata
    16801 ctttacaatg atgtctggaa atgatatgta tgaagctact actgtaatcc ttgcaactgg
    16861 ggtagagtat actagaccaa tcaagggtga agaagaattt ctaggaagag gtgtgggcta
    16921 ctgtgctaca tgtgatgcac cactttatag aaataaaaag gtagcagtta taggatataa
    16981 tgaagaatct aaagaagaag caaatttttt aagtgaactc acttcaaaga cttattttat
    17041 acctatgtac aaaaaagata atcttatgag aagttcagat aacctagatg attctattga
    17101 agttatacat gacagaccag tacagataga tggagataaa cttgtaaaca aagtatcttt
    17161 taaagaaaac cacattgaag ttgatggagt attcgttata aaagatagta cggctccaag
    17221 tgcattggtt cctggaatag agattgatgg cattcatatt aaagttgaca ataatatgaa
    17281 gactagtata gatggatgct ttgctgctgg agattgtgtt ggaaaaccat attcttatat
    17341 aaaagcagct ggtcaagggc aaatagcagc tttaaatgct gtttactatt tagataaatt
    17401 aaagagggct taatatttat attgattaac tttttaaaga tatttataaa aaactgtctt
    17461 gaaataattt tattatttca agacagtttt ttatttttaa gttattaata aaagtatttt
    17521 aaaatctata tgtaattact tttattaata aaactcaaag ttatattagt aaaaattgga
    17581 attatttata atatactcca aaatttaaaa ataatggttg aaaaatctaa ttaagagtac
    17641 tataatttaa ttaagtaatt acttaatcaa aacgaggtac ttatggaaaa cttggttaaa
    17701 atatttaaag cattgagtga tgaaactaga cttaacatac ttatattagt atccaagaga
    17761 aatatatgtc aaaaggggat ttctaaatat ctagggattt cagattctgc tgtttcacaa
    17821 catataaaaa tattaaaaga tgttgggata ataacaggat ataaagaagg atactatgtt
    17881 ttatatcata ttaataaaga atcatttaat atatgtgtag attttataaa ttctatgtta
    17941 agtaattcta gtgaaagctt tatagatgta tttgatgtaa atacaataca tctaggatgc
    18001 agtaaagaat gtaaatctat aaaaaaatgt tgtaagagaa gggagaaata atgatgaaag
    18061 tatgtatacc agtagaggag aataaaggat tggatagtaa accatatgga cattttggtt
    18121 ctgctccaat ttttgttgtg tgtgatttag aaagtggaga agttaaatct ttagataatg
    18181 gagatttaga tcatgaacat ggaaaatgtc aaccattaaa agcattgtca gggacagctg
    18241 tagatgcagt agttgttgga ggaataggac aaggagctat aattaaatta aatggaatgg
    18301 gaataaaagt ttacagagca gaaggtgata ctataagtgc taatttagac ttacttaaaa
    18361 atggaaaatt agtagaattt ccatcagacc atacttgctc acatgacgga tgtgggcatc
    18421 attaaaaaaa acagctgatg aaatatatac ttcatcagct attttttctt ttaataaata
    18481 cgattttatt cttttaaaac caaaatttag atttttatgt tttttgtagt atccttaata
    18541 atatttcaag tttacaagtt tactactttt agattttttt ggtatgtttt tctatatagt
    18601 caatatcatt taatatgtca ttgagttctt tattaagtgt ttttaaatca tcaccatcta
    18661 cattgtagtt taaaaatagt tcctctacat tatcaatgat agaattgacc tttctagtaa
    18721 cttcaacaaa tgtcttaaag ttactactat ttttagcatt tagaaatttt tttaaatcct
    18781 ttgatataaa tgatactatt tcatattcat cattaaatag acctctacca ataggatatg
    18841 gttcaattct ctgtaaaaaa tattggtctt tagcattaat attataagta taagatattt
    18901 cccaaccgtc tcctaaatca aacttgataa aatataatgt actacttact tttgatattc
    18961 ttgtggcacc aagctgtctt aaaagaactt caatcgaatc accttgaaca gtattaatat
    19021 tcatatatac acatcccctt tagtattatt atactatatt ttttaaaatt ttataattaa
    19081 ataaacagta gatataataa tggatataat cataagtgga aaacctattt tgaaatactc
    19141 cttaaaagag ataggatgac cgtgtttatt acctatacct gctagtacaa cattagcaga
    19201 tgctcctatt agtgttccat ttcctccaag acaagctcca agagatgttg cccaccatag
    19261 tggcattaca tcaatacctt cagcttgcat agtcaaaata agaggaatta gtgttgcaac
    19321 aaatggaata ttatctaaga aagaagagac tatagctgac aaccataata tcaacaacat
    19381 tgtaaataca agatgtcctt ctgtaagtcc aatcaatgct tgagccaatt tgtttattat
    19441 cccaacttct actaatccac caactactac aaataatccc ataaagaata aaattgtaga
    19501 ccattcaata cctgccataa tttcatctac atcttgtttt cctattaaaa gcattataga
    19561 tgctcctgtc agtgctacaa cagaagaatc tatgtggatt gtactgtgaa acataaaacc
    19621 aaaaagtatg aatgctatta atataaggct ttttataagt agaggtttat ctttaacaga
    19681 ttttttttca tctagtttta atattgcatt tttagctctt tcattcacaa caagttcttt
    19741 tccataaata aatctaaagc atattatagt tatagcaagt attactataa cagcaggacc
    19801 taaatttatt acaaaatcca taaaactaag attggcagca ctaccaatca taatatttgg
    19861 agggtctcct ataagagtag ctgttcctcc tatatttgaa gctaaaatct gtgttattaa
    19921 aaatggaact ggattaagtc ctaatatttg tgtaataact atagtcattg gtccaataag
    19981 taagacggtt gtaacattat ctaatacagc tgataaaata gctgttataa tagcaaagca
    20041 aatcattatc ttccatgggt cacctttggc tttctttgca gtccagatag ctatatattc
    20101 aaataacccc gagtttttga caacagctac aaatagcatc ataccaacta atacaccaat
    20161 agtattgaaa tctatatggc ttaatccttc atcaagtgta agtatattga atattatcat
    20221 taatagtgca ccaccaacag ctgctacgga tctgtttacc ttttctgtaa taatagctgc
    20281 cataactatt aaaaatatac atatagctat tatttgttga aattccataa tataagtacc
    20341 tccatttgta ttattttgtg cctaatgcta gtactatata tagtattact tttttattgt
    20401 tttttcaatg gatgtatgaa agtatattat ttaacaaagt ttttgaaaaa ttgacagaat
    20461 ttaaagaaaa tttttgttat ttaaataaat tttaaaatta ttccattgat aataatatta
    20521 aacgacaaac gaaaaaatat accctttaaa ctagaattta ttgtatccaa taacaattat
    20581 aaaatattaa atatatctat attataaaaa caataaaaaa aggtttgatt tgaatataaa
    20641 actgcaatat attaaaaaaa ttattcattt taaaccttgt aatttgattt tataaatatt
    20701 ataattaaat taatgaattt ttaacaagga attattcatt tttttgattt taagatttat
    20761 tgagaaaaca aaactaaata ggggggtaat taatataatg gattttttca atggtatttt
    20821 aacgagtatt aacaatgcag tagtatatgt aaacaattac ttatggtcgt atatcttaat
    20881 tataatgtta gttgtaattg gtatttactt tactattaaa acaaattttg tacaattcag
    20941 atattttata gaaatgttta gacttctggg tgatggtaca gcgaataaaa atgcaaaaaa
    21001 ggaaggaaaa atctcttcat ttcaagcatt ttgtataagt acatcttcaa gagttggaac
    21061 tggaaatata gctggaatag caattgcagt ggtagcagga ggacctggtg ctgtattttg
    21121 gatgtggctt atagcattaa ttggttctgc atcaagcttt gttgagagta cattagctca
    21181 gatttacaaa gtgaaagatg gtcaagcttt tagaggtgga ccagcgtatt atatggaaca
    21241 aggtctaaat aaaaaatgga tgggtatttt attctcaata cttataacta tatgttatgg
    21301 ttttgtattt aatgcagttc aagcaaatac tgtttcactt gcatttaata atgcatttgg
    21361 aataagtaaa atggctatgg gaataggtct tggaatttta actgcaatag ttatttttgg
    21421 tggagtgcat agagttgcaa aagtttctga aataatagtt cctgtatttg caggattata
    21481 tatattagtt gctttggcta tagttgtaat gaatataaca gagataccaa gtgttatagc
    21541 attgatagtt gaaagtgcat ttgattttaa aggaatggcg attggtacgt ttatgggagt
    21601 tgtaatgact ggagtgaaga gaggtctatt ttctaatgaa gcaggtatgg gtagtgctcc
    21661 taatgctgct gcaacagcac atgtaactca tcctgtaaaa caaggtttaa ttcaatcttt
    21721 aggtgttttt acagatacta taataatatg tagttgtaca gcattcatgg tattattata
    21781 ttcaggttat agtagtagtg gagcaactgg aattgaatta gctcaagaag ctttaactca
    21841 tcatatagga ccagttggaa atatatttat agcagtttgt atattcttgt ttgcatttag
    21901 ttctatagtt ggtaattact attatggtga atcaaatatg gagtttatga gtggaagtaa
    21961 gactaaactt aatgtattta gagtttttgt tgtaggtatg gttttatttg gttcacttac
    22021 tcaagtagat gtagtttgga atcttgcaga cttatttatg gcattgatgg cgataataaa
    22081 cttaatagca atagcacttt taggaaaata tgcatttatt gctttaaaag attatacaag
    22141 tcaaaaaaaa tcaggaataa aagaccctgt gtttattgca gatgaaatag aaggcctaga
    22201 aaaggtatca gagtggcata gggaattatc tgaggaacat ttaggataaa aaatagtata
    22261 aaattataaa accattttga aagactagag tatgtatata ctttatatga atataatatt
    22321 gaattaattt atattactgg aatttttaat tccagtaata tttttttatt atataattta
    22381 gctttattaa aagtttttat tattaaaaat agcttattta tcgtaaagtg aatgatattg
    22441 ggcttttaat tattatgaat gttagtattt aatttaaaga cttaaataaa tttgccattt
    22501 ctagcgcatt catagcacaa tcataacctt tatttccagc ttttgtacct gctctttcaa
    22561 tagcttgttc aatattttct gtagttacga ttccaaatat aacaggtaat tcactgtcta
    22621 aagatacttt ggctatccct ttagagactt cactacatac ataatcataa tgagaagtag
    22681 cccctcttat aacacagcct aaacagatta tagcatcata cttaccactt ttagccattt
    22741 tttgagcaac aagaggaatc tcaaaagctc caggtaccca aactatttct atattttctg
    22801 gagaaacgtc atgtcttaaa agacagtctt cagctcctga taaaagtttt gatgttataa
    22861 attcattaaa acgagaattt attataccta tttttaaatc ttttccaata agttttcctt
    22921 catatatcat ttttatttcc tccaatttta tttatgttat agatttatat ttataaatat
    22981 ctttaattta attataaaaa actacttagt agaaaaatat catcatataa tcatttatat
    23041 aatatctaaa agatgtccca ttttatcttt tttagttttt aaatatagct tattaaagtc
    23101 attaatttct tcattaatag ggattctatt ttcgattttt attccatatt tctctaattg
    23161 atttatttta tctgggttat tacttaaaag atttatactt tttatgttta aattttttaa
    23221 tatttgagca gccatataga aatctctcat atcttcttca aatccaagca ttaaatttgc
    23281 ttcaacagta tcgtaacctt cttcttgaag tttataagcc ttaattttat ttaaaagacc
    23341 aatacctcta ccttcttgct tcatataaat taaaactcca cttccatttt ccacaatttt
    23401 cttcatagaa gattctagct gtaatccaca atcacatttt agagagtgga acacatctcc
    23461 tgttaaacat tcagaatgaa gtctaactag agtattttct atatttatat ttccataagt
    23521 aagggcaatg tgttcttcat ttgaataagt atctctatat cctatgattt caaaatttcc
    23581 atattttgtc ggaaggaaag cactagatac tttttctata gtagtttcat ttattttgcg
    23641 gtattctata aggtctttta tagtgatgat ttttaaatta tgcttttctt tgaaaatcat
    23701 taaatcatca actcttgcca ttgtaccatc atctttcatt atttcacaga taagaccaat
    23761 ctctttaaaa cctgcaagtc tagcaaggtc tactgaggct tctgtatgtc catccctgac
    23821 aagaactcca ccagtttttg ctattaaagg aaagatgtga ccaggcgttt tgaaatcttt
    23881 acttgtagaa ttttcatcac agaataattt tacagtttca gctctttcat atgcagatat
    23941 accagttaga gtatctgctc catctatagt aacagtaaag gctgtttgaa atgtatctgt
    24001 attttctcta accataagag gtatattaag acttttaaat tttttttcag tggcaggtag
    24061 acaaattaga cctctaccat atgtagccat aaaatttatt gattcaggag tagccatttc
    24121 agctgccatc aataaatctc cttcattctc tctactttca tcatcaacta cgattaccat
    24181 tttcccattt tttatatctt caatagcttc ttcaatagta ttaaacatgt aattcactcc
    24241 tttattattt ttaaaaacca tttttaaata aaaaatcttt atctatattt gatttatggt
    24301 tactactatt agaatttaat tccttgtagt tattagccat aaaattatta acatactttc
    24361 caattacatc gctttctaaa ttaacgaaat ctccaacatt ctttgtcaag agaatagtgt
    24421 taattttagt atgaggtata atagaaacct taaatatttc atcatctaaa tatgatatag
    24481 ttaaacttac accatcaata gcaacagaac ctttgagtat cattgaggat aaaagttttt
    24541 tatcaggtcg tatacttact aaaactgcat tttcatcttt ttcaaatttg cagatagttc
    24601 ctttaccatc aacatgacct gttactatat gaccaccaaa tcttgaagaa agactcatag
    24661 ctctttcaag atttaccttg tcatttgcat ttaataaacc taaatttgtg gaacgaattg
    24721 tctccatcat aacatcggct gtaaattcat tttttccgag gtttgaaaca gttagacaaa
    24781 ctccatttac ggctatacta tctccaagat ttgtgccatc taatatttta tttgatagta
    24841 tggttacttt tccactctta ccattagcag taatttttct aagtattcca acttcttcta
    24901 ctatgccagt aaacatccta acctcctata tgaatgtatt aacaaaaatt taatttaaaa
    24961 catctgattc tataagaata tcgccatcta tcaaagttac attattgatt gttaactgtg
    25021 ttgaatctga caaatgattt attccttctc cagaaacgaa tgtaggtgca tctttaccac
    25081 ctataatctt gggtgataga aataatttga ctttatcaac taacttattt ctaaagagac
    25141 tgtcattgag agtagcacca ccttcaacta gaacagaatc aatgtttaac tctcctaatt
    25201 tatacattac aaactccaaa tctactaagt tgttttttga aggagaaatt attgtttcaa
    25261 cattattttc ttttaacata gataatttta tactttcttt gcaacatgtg aaaactatag
    25321 ttttactggt tttatcttta accaaattac tattaagtgg caactttagg tgtgtatcta
    25381 ttactattct tgtaggatga gacacttttt cttgattgag cctacaagtt agtaaaggat
    25441 tatcgttcaa aactgtattt atgccaacca ttatactttg gtatttattt ctgtatttat
    25501 gagttagata ccttgatgat tcattagata tccattttga ttctagtgat tttgtggcaa
    25561 ttttaccatc tagacttact gctgatttta caatacaaag aggtcttttg ttttttatat
    25621 gataaaaaaa tgcctcattt aaatctcttg cttcatcttc taatattccc acagtaacat
    25681 caatattgtt atcttttaat ttttttactc cattaccaca aacaagtgga tttgggtcta
    25741 atgtagatat tacaactctc ttaatcttat tttgtataat tttatctaca caaggaggcg
    25801 ttttcccata atgagaacat ggttctaagt ttacataaag agtagagtct tttagacttt
    25861 gtttagcact gtttatagca tttacttcag catgattaga gccaaatttc tcatgatatc
    25921 ctttgcctat tatattacta tctttaacaa ttacacaccc aactaatgga tttggattta
    25981 caaagccttc tccattttta gccaattcaa tagctttttt catataataa atatcttttt
    26041 ctttttgatt cacaaaattc acaatatgta cacctcctgt ttaattggat aatttttaaa
    26101 caaaaaaccc tgagaattaa ctcagggttt agaataatct acaataaatg tttaataaat
    26161 gtagaacaaa attgctctac aaaaacactc attaaatatc ttcttccatc cagactttac
    26221 tgtcggcttt ggaatttaac caaatcaacc aagttttaca ttggctcgcg ggctataccg
    26281 ccgattggga atttcaccct accccgaaga ttaagtatta aatttatatt tagaatgtat
    26341 cataaattat tttactttgc aaactatttt tttaaaaaat atatgttaat atataatata
    26401 gaatgtctat aaactttgaa ataccacgat tgtgaatata aaaataaaaa tttgaacata
    26461 atcaggaaag aagtctaatt aatttaaatt aggagagtaa tatatgaata aaaaactttt
    26521 agaaatacta tcaaaatact atggatatac aagttttaga aaaggtcagg aatctataat
    26581 aaattctatc ttaagcgaaa aagatgtgct agctattatg ccaacaggag ggggaaaatc
    26641 aatatgttat caaattccag ctttgatttt agatggaatg acaatagtaa tttctccact
    26701 tatatcactt atgaaagacc aagtagatgc cttaaagact atgggaatta gtgctgcttt
    26761 tataaatagt tcattaagca gcaaagaatt taatgaaata ttaaataata ttagaaaaaa
    26821 taattataaa atactctata ttgctccaga gagattagat gcacaagagt ttattgagct
    26881 aataaataat aacaatgtaa gtcaagttgc gatagatgaa gcacattgtg tatctcaatg
    26941 ggggcatgat tttaggttga gttatagaag gatttctgat tttataaaaa atttgcctaa
    27001 aagacctata gttacagcat ttactgcaac agcttcagaa gaggtaagaa ctgatataat
    27061 aaatttactg tgtttagaaa atccagatta ttatataact ggatttgata gagagaattt
    27121 atcaataaat atagtaaaat catctagtaa aaataagtat attttagatt atattcaaaa
    27181 tcataaaaat gagtctggaa ttatatatgt tgcaactaga aaggaagttg aaaatatata
    27241 taatggttta tctaagagaa atatatctgt atcaaaatat catgcaggtt tatctaaaaa
    27301 tgaaagaagt aaaaatcaag aagattttat aaatgataat gtggatataa tggtagcaac
    27361 aaatgcattt ggaatgggta ttgataaacc taatataaga tgggttatac attacaatat
    27421 gcctcaaagt atagaaaatt actatcaaga aataggtaga gctggtagag atggagaaaa
    27481 aagtgagtgt gtacttttat tttctccagg agatgtacat atacaaaaat atttaattga
    27541 tattggagtt gaaaatcctg aaagaaaatt atttcagcat aagaagcttc aatacatgat
    27601 tgacttagtt tacagtaatt catgctatag aaagacaata ttgagttatt ttggagaaaa
    27661 ttatatagac aattgcaata attgtagcaa ttgtttagta gagggtgaaa tagtagataa
    27721 aactatagat gcacaaaaag tcatttcatg tgtagctaga atgaaaagaa gttatggtgt
    27781 tactactatt gtagatgtgc ttagaggttc taagaataaa aagattttac agcttggatt
    27841 aaatactttg tctacatata acattatgag agattattct agtgaagact taaagaattt
    27901 tataaataca ttggtttctc atggtttttt agatttagtt gagactctag gcaatggaaa
    27961 tagaggtagt tttcctacta taagattaaa tgagatgtct atgaaagttt taaaaggtga
    28021 agtgaaagta gagtttaaag aaattgttat gacaaaatca ttggaagtag aggatgagtt
    28081 atataatgct ttaagagaac ttagacattc aattgcaagt gaagaaagga tagctccata
    28141 tatggtattt ggagatggta cacttagagc catgtctagt agttatccaa ttaataaaga
    28201 agaaatgcta gatatctctg gagtaggaga aattaaatat caaaaatatg gtagagattt
    28261 tgaagcagca attaaagaat atgtcgaaaa aaataatata aataaaaaaa tagatgaaaa
    28321 aaatgtcgat tcaaagaacg ttaatagtga tttcttagag gttaatacag ataaagtttt
    28381 atatgaaaaa ctgttagtca ttagagaaga atatgcaaca aaggaaaaat tacctgcata
    28441 tatgatttta gccaataagg ctctgaaaga aataagtgga agatatccac ttgatgaaga
    28501 acaattaaaa gatatttctg gcataggtgg agtaaaattt gaaaaatatg gagctagtat
    28561 tttggcagag gttaataaat atgtaaaaga aaataatatt aatgttattt gggagaaaaa
    28621 gggcaaaagg aagttaatat tagatggaga aagtagaaaa aataatgaaa tagcattaga
    28681 tttgctaaat caaggaaaag atatacaaag tatcagtcaa gaaatagaag tttcactgtc
    28741 aaccattatt ggatatgtgc atgactatgt aaaggatgga catagtatat catttgaatt
    28801 aggactagaa aatttttata atgaagataa aaagaagatg attttagaag tttgtgaaaa
    28861 agttggctat gataatttaa ataacataaa aagaaaactt ccagattcaa taaagtatga
    28921 aaatataaga gctgtgatac ttgactctta tcttgaaaac ttaaaaaata atattatagc
    28981 agagtaattt ttaacttaat aaaaaataaa atttgtatta ttgtgttgaa ctaataattt
    29041 tgctgtgtta tactgaattt gtaaaaataa tgaaaaatta gagctagggg cgctagaatt
    29101 ggctagctga gagataaagc cgtaacttac aaaccctaat aacctgatca agataatgct
    29161 tgcgaaggga agctttttaa tataatttta ttatataaat aggcaaatta ttcaatgtta
    29221 ggagaaattt gtctaagtgt atatacgatt ataagagtgc tttccaaacg aggaaaagca
    29281 ctttttttat tttcaaaaac tataacttta atcttggagg attgtaatat gaactataca
    29341 acacaaatgg atgctgctag aaaaggcata ataactaaag aaatggaaat cgtttctcaa
    29401 aaagaacagg tagatgtaaa tgaattaaga gaattaatag caaatggaca agttgttata
    29461 ccagctaata aaaatcataa atctttaagt gcagaaggtg taggtaaaaa tttaagaaca
    29521 aaaataaatg taaatctagg aatttcaaga gattgtaagg atatagaaaa agaacttgaa
    29581 aaagttagag tagcaataga catgaaagct gaagctataa tggatttaag taattatggc
    29641 aaaactagag aatttagaga aaaggttgtt gaaatgtcac ctgcaatgat aggttcagta
    29701 cctatgtatg atgcagtagg atatttggaa aaagaattaa aagatataac agaagaagag
    29761 tttttaaatg taataagaca acatgctatt gatggagtag actttattac tatacatgca
    29821 ggtcttacaa gaagtgtttg ccaaaaaata aaaaatcatg agagattgac tcatatagta
    29881 tctcgtggag gttctttatt gtttgcatgg atggaattaa ataataagga aaatcctatt
    29941 tatactaatt ttgataaaat attggatata tgtgaagaat atgatgttac attgagttta
    30001 ggagatgctt gtagaccagg ttgtataaaa gattctactg atggtgttca aattcaagaa
    30061 cttgtagtat taggtgaact tactaaaaga gcatgggaaa gaaatgtaca agtaatgata
    30121 gaaggtcctg gacacatggc tattgatgaa atagaagcaa atgtagtatt agaaaagaga
    30181 ttatgccatg gagcaccttt ttatgttctt ggaccattgg ttacagatat agcaccaggt
    30241 tatgaccata taacaagtgc aataggagga gctttagcat gtgctaaagg agtagatttt
    30301 ttatgttatg taactccagc agaacattta agattgccta atttagatga tatgaaagag
    30361 ggtataatag ctgcaaagat agctgctcat gcaggagata tagctaaaaa tgttaaaggt
    30421 gctcgtgaat gggataataa gatgagtaaa gctagagctg atttagactg gtgtgagatg
    30481 tttagacttg caatagaccc tgaaaaagct aagagataca gagatgaatc aactcctact
    30541 catgaggata gttgtactat gtgtggaaaa atgtgctcaa tgagaacagt taagaaaata
    30601 ttaaacaatg aggaacttaa tctaatataa tttttggcta gtatgactgg aataaaaaga
    30661 agctgaaaag aggaggtgat ttagtgaagg ttaatgggaa ggaaattgaa tttgaaaaag
    30721 atttgactgt tatagattta ttaaataaat ataatttaaa aagtgataga gttgtagttg
    30781 aagtgaattt agagataatt gaagaatcta actacaatac atatgtatta aaagacgagg
    30841 acattgtaga gcttattagc tttattggag gtggttaaaa taaaaatatt tgtaaatgaa
    30901 ttattaacag atgttgagga aaatataact gcttataaag ttagagatag ctataacaat
    30961 aaatgtgatg tattggtgtt aaatggatat ccaattaaaa cagatatgcc cctttgtgaa
    31021 aatgataaat taacacttat acaaaaagga gttaagccat cacttgatga attggaaagc
    31081 ttgttgattg ctagacatac tccaaatata cataataaat taaaaaaagg gaaagttgct
    31141 atattgggat tggggggact tggttccaat atagctatct ctttagctag aataggagtg
    31201 ggagaacttt tacttataga ttatgatgtt gtagaaccat ctaatttaaa tagacagcag
    31261 tattttatag atgatatagg aaaactaaaa actgatgcca tgatagaaaa tataaaaaaa
    31321 ataaatccat ttataaaatt aaataaacga gatatttttt taaacaagaa caatatggat
    31381 actattaagg attcagattt aataattgag gcctttgatg atgcttcatg taaagcacag
    31441 gtatgtaatt atgtattaat aaatttaaaa gataaatatt taatagcatc atctggtatg
    31501 gcaggttact atgattcaaa tataataact actaagaaga taaaagacag gttttatata
    31561 tgtggggatt ttgtgaatga agctaaattt ggtgaagggc ttatggctcc aagggttgcc
    31621 atctgcgcaa atcatatggc aaatttggca acgcaaatac ttatagatat gtaaatatta
    31681 aaattagata taaaaaagat tgaatattaa aaaaatttaa cgtggaggga aataatatgg
    31741 ataaattgat acttggtgga catgaattta atagcagatt attggttgga acaggtaaat
    31801 atggttcaaa taatatattg cctgaggtaa taaaagaaag tggaagtgaa ataataacaa
    31861 tggcacttag aagagtggat ttagacaata aacaagaaaa catattaacg tatattccaa
    31921 aagagatgac aatacttcca aatacatcag gagctactaa tgcagaagaa gctgtaagaa
    31981 tagctagaat atctagaaaa atgggatgtg gagattttat aaaaatagaa gtaatatcag
    32041 atactagata tttacttcct gataatgaag aaactataaa agctacaaag atacttgctg
    32101 atgaggggtt tatagttctt ccatatatga caccagacct ttatgctgga agaagactta
    32161 tagaagctaa tgcagcggca gttatgccac ttggagctcc aattggttca aatagaggtc
    32221 ttcaaatgaa agaaatgata agaataatga tagatgagtt ggatatacca ataatagtag
    32281 atgcaggtat tggaaaacca tctcaagcta tggaggctat ggaaatggga gctgatgcag
    32341 tacttgtcaa cactgctata gcttcagcag gagaccctgt acaaatggct agagcattta
    32401 aattagctgt agaaggtgga agagaagcat atattgcaaa aacaggaaat gtgtcagaat
    32461 ttgcaaatgc atcttctcct ttaacaggtt ttttaggcaa tttatagaaa gtggtgattg
    32521 gtgatgagtt tttatgatgt aatagaaaaa tatagggatt ttgattttga tggatattta
    32581 aataatgtta ctgataatga tgttttaaga agtttatcaa aagacaagct tgaagatttt
    32641 gatatattaa atttgctttc taaaactgca gtaaaacatt tagaagatat ggcacaaaaa
    32701 gcacataaat taagtgttca atactttggt aaaacagtat gtttatatac accaatgtat
    32761 atagcaaatt attgtgttaa tcaatgtgtt tattgtagct ataatataaa gagtggaata
    32821 aaaagaaaaa aattaactat ggatgaaatt agagaagagg gagaagcaat ttcaaaagaa
    32881 ggtttcaaac atctacttgt tttgactgga gaaagtagtt ttcactcaag tgtagaatat
    32941 ataggtgagg ctatagaaat attaagagag aaatttccct ctataggtat agaagtttat
    33001 ccaatggaag tagaagaata taagtacatt gtagataaag gtgttgaagg attaacagta
    33061 tatcaagaaa cttatgacga ggaaatatat aagagagtac atataaaagg cccaaaatca
    33121 aattataaat ttagactaga tgctcctgaa agaggggcaa aagcaggtat gaggacttta
    33181 tcaataggtg cacttttagg gctaaatgat tttagaaaag aaactttttt tacaatattg
    33241 catgggaaat acttaaaaac gaaatatcct catattgagc tttcatattc aacaccaaga
    33301 atgagacctt ttaaagggtg ttttgaggaa ttggtagata taagtgatac tgatttagtt
    33361 caagctatgg tatgtatgag attatttgac cctcatgcag ctataaacat atccactaga
    33421 gaaaatttag aaatgagaag tcatataata cctttaggag taactaaatt gagtgcaggt
    33481 gtatctactg atgtaggagg tcattctcaa gatgaacatg atactgctca atttaagata
    33541 aatgatgaaa gtactgttaa agatgtggag aaaatgctaa actcaattgg ttatcagcat
    33601 gtgtttaaag attgggaaag attttaaatg tatctgataa caaacagaaa attatgtagt
    33661 gaggaacgat atttagaagt tattaaagag tctatattga gtggtgtaga aaatataata
    33721 ataagagaaa aggatttaga atatcaagag ctaagaaaat tatatatgaa aataaaaact
    33781 aaaatcaatt gtatagattt tcaagagcaa atatcagatg aaagtttgaa aactaatata
    33841 aatcaaaaag agtttagaaa taaattcaag gttaatttta taataaatag taacattgaa
    33901 ttttttgaaa aagtggattg tcaaggtatc catcttcctt ttaaattatt cttgaattta
    33961 attgaaaata agtataattt taatgaaaat aaaatactag gattatcttt acataaagta
    34021 gaggaagtag attatttaga aaaattaata agaaatcaaa atataaaaat agattacata
    34081 acattatcac atatatatga aactaaatgt aaagaaggat taaatccaaa aggaattgag
    34141 cttttaaaag aagctaaaaa gattactgat attaaaataa ttgcacttgg gggaatttta
    34201 ccatctaatg tcaaggaaac attaaaatac tgtgatgatt ttgctataat gtcaactata
    34261 atgaggtcta aagatattaa aaaaaccata tcaaattata atgaaaagtt gaattagtaa
    34321 atatagtata ttgaattttt aacttaaata aaaataaaaa agttatcttt taaattttaa
    34381 aaggtagctt ttttatttta tatctttgct aataaaaaat tgtaaaaagg gaaaacttta
    34441 gtcagagaga ttaaacaata tcctagaaag atttaaaatt tagtaaagta tggaggacat
    34501 tataatgact gacagtaaaa agaaacgatt tattatacca cacactttta caataatatt
    34561 tttactaata gtcttgatgg caatattgac ttggatagta ccaagtggtg aatttagtag
    34621 agaagatgta gaaggtagaa tggtagttgt accagggact tatcaaagtg tagaaagtaa
    34681 tcctcaagga tttgcagatg tttttaaagc accaatagaa ggctttatcg attcagctga
    34741 agttgtaggt tttgttttaa tagttggagg tgcttttggt attgtaaata ggactggagc
    34801 tatagaagca ggaatagctt cggttatctc taagtttaag ggaaaagaac ttcttataat
    34861 tccaatatca atgattttat ttggacttgg aggtacaaca tttgggatgg cagaagagac
    34921 attaccattt tatatgatat ttgttccact catgacatcc ttgggatatg attctctaac
    34981 agcaatagca attgtattta taggagcagc agcaggagca gccgcttcaa caataaatcc
    35041 attttcagtt ggtattgcac aggcactagc tcaacttgct cctggttcag gagtaactta
    35101 cagagtagtt atttttatag catatatact aataagtata gcatttgtta tgtactatgc
    35161 taagaaggta aaggaaaatc ctgaaagttc aatagtatat gaaatagata aaaataataa
    35221 atcaatactt aatcaaactt caacagaaat aaaagaattt acttttaaag aagtatctgt
    35281 tcttgctata tttggaatag ggatggcaat aatgatttgg ggtgttttaa gtcagggatg
    35341 gtacattcca gaaatatcaa tgtgttttgc tgcaataggt gtgctttctg gattggttgg
    35401 tagattatct caaattgaaa tctcagaaag ttttatagat ggagcaaaag atttagcatc
    35461 tgcagctctt gctatagctt tggctcgtgg aatcgtaata attgctcaaa atggatttat
    35521 aatagatact atattaaatt ccgcagcagc ctttctaggt gggcttccaa aggttatatt
    35581 tgtatattta tcatttttct tggaagctgc attggcattt ttaattccat catcttcagg
    35641 tcttgcttca cttacagtac ctgtacttgc tcctcttggt gatttggtta atatatcggc
    35701 tcaagtgata gtaaccgctt atcaatttgg tgtgggtctt acaaacttta taactccaac
    35761 ttcaggagta ctgatgggag cacttgcagt agcccatatt ccattttcaa aatgggtaag
    35821 atttataatg cctatcttgt tgattttgac agctgtatct ctagtctttt taacaatagg
    35881 tatttatata gggttttaat taagtgtagt tttatttaag atatttagta atggtataaa
    35941 atgataatat gttttcaata aattgccact aatttaatta gtggtaattt gttttttgta
    36001 tttaaaaata aatgtattta cttgtatttt gaattaatat ctacatagac attgttttaa
    36061 ttgttatatt ttcatttaat taagcattga tttatcattt tttatatttc atataacaat
    36121 gcaaaaaata atttttatat agtaaatgac aaaagtttac aataaatgta tattttctta
    36181 ctcattcctt aaaattactc atttagttta ataactctca tttcatatgt aaagttggta
    36241 aaaaaattaa aattaaaagt aaaaaactaa ataaattaat gttaatttga aatatatatg
    36301 aaggtttttg gagaatactt acttatgata ggaaaaaatg ttaaaataat agtgtaatca
    36361 aatataaagg actgaaataa ttaacagtta ttaaatatta ggagtgtaaa aatttatggg
    36421 attaaaagaa tttgatttta ttgaagagtc tattgatatg ttgaggacaa tgtcaccaac
    36481 attagaaact atatcagatg aaatagaaga gtattttgaa aatatcttgg atgaaaagaa
    36541 tcaagaatat ataaatgtaa cctctagaat aaaatcagaa tcaagtttaa gagaaaagat
    36601 aattagaaat agatatttaa aaaaatatgg agaagcaagt aatcttattc ataatgtttc
    36661 tgacttaata ggcctaagaa ttgagtgtag atttattgag gatgaaaaca aaatatatag
    36721 acttttgaga agatatttta ataaaacaga tgacaaaata aactattata ataaagagaa
    36781 taagaatatt aaattaaaac tatctgagag gcaacccaat aaacaaaaaa atggatttga
    36841 aatatataaa atagatggag tttttgcgta tttagataga gaagtaaaat ttgaacttca
    36901 aattaaatct cttgtaaatg tgttttggag tgaaatagaa cataaaataa tttataaaaa
    36961 caatacatat ttacttgctg ataaatttat aaaggatatg atggactcta taaagaataa
    37021 tcttactatg atagataatc agcttttaag tatttataaa aactttcatt cagggaagtc
    37081 ttttaatatg aaagtaagta aaaaagaaat tgaaaaatta tttgcgaaat tagtctatga
    37141 cgctttttct gaaaagatga ataaaagtat aggttttgtt gtagatttta aaaaaccatg
    37201 tgagactata ttgaactatt cttttaataa acaagatata agtgatgaag ttttaggtaa
    37261 ttttatgctt gatgagtttg caagattaaa tgaaattgta aacaaggata tagattttaa
    37321 tgagcaaata gaatttgaaa gagaaccaac atttgatgat aagttttgta aagacctagg
    37381 aaatcatttt agaagtagat taaacacaga atttccatgg aacctatttt ttagaatatt
    37441 atttgaaata gagccatata acaataccaa agactttgaa aactttgtag agtttataaa
    37501 agaaaatgtg ctactagaag aaaataggga gcaattatta tgccaatttg aagaagatag
    37561 caaacttata attgaagata tatatgattg tatatttaat agtataagtg agattgatag
    37621 tgttgaaatt ttatataact ataatcttga aaaaataaac tttacatcaa gtgaaatcat
    37681 aaattgtata tgtagagaat atgagtgtta tggtgaatac ttagaagaaa aagaaaagct
    37741 tatgaataca tttaaagaaa agattattca aatctttgaa taataggtta atgctgaagt
    37801 ggcgctaatg cgccattttt caaatatata tgaattaagt aaaattattt tggaggaggc
    37861 gatttgtata gagaaaacag gtgtaatttt ggcaggggga agaaattcta gaatgggtag
    37921 agataaagcc tttttagagt tacatgataa gctttttatt gaaattgcaa tagaagcatt
    37981 taaaaacttt gatgagttga taataatatc taataatgaa gaattatatt ctaaatacga
    38041 tattaaagtt tataatgata tagtaaaaga tgttggtcca attggaggaa tatatactgc
    38101 tcttgaatat gcaaagtatg atatagttac aattgcatgt gatatgccat atctaaataa
    38161 tcaaatagtc gaaagaatag ctaataaaat gaatgataaa agtgtgattt cagtgacaaa
    38221 tggaaagtta caaccattgt gttctggata taaaaagagt ataataaata aagtatcttt
    38281 atgtataagg gaaaatgatt taaagctcag aagctttata gataaaatag ataaaagtta
    38341 tatatacttt gatgaagaag atttattttt aaatgtaaac actgttgatg agtatgaaaa
    38401 attaactaaa gtttaattag ctatggttgt aaaatagagt aggatttata tggaggagag
    38461 tttatgaatt tacttaaatg cgattcttgg gcagtaatat taaataatag cgataaagaa
    38521 agtaaagcat ataaaatatt agatgaactt aaaaggaata tgtacaaagt tgttgctata
    38581 gatgaagaga aaaaacctat tgaaggaata gatgtgtatg aatgtttaaa agatgttcca
    38641 cacaatattg atgttgtagc tattattgat aaacaatcta agatggatgt gattttagaa
    38701 gaagtagagc ttttggatat acaaaatatg tggtttgaaa aaggaagctt tagtgaaatg
    38761 atgattaaaa agactaaaga tttaaaatta aatataga
//
LOCUS       DAEOTL010000034        37869 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEOTL010000034 DAEOTL010000000
VERSION     DAEOTL010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37869
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.034"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(297..1178)
                     /locus_tag="KRH82_002026"
     CDS             complement(297..1178)
                     /locus_tag="KRH82_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBG8655305.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
     gene            1634..2608
                     /locus_tag="KRH82_002027"
     CDS             1634..2608
                     /locus_tag="KRH82_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655306.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(2724..3785)
                     /locus_tag="KRH82_002028"
     CDS             complement(2724..3785)
                     /locus_tag="KRH82_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBG8655307.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKAPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(4397..5248)
                     /locus_tag="KRH82_002029"
     CDS             complement(4397..5248)
                     /locus_tag="KRH82_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8655308.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(5265..6185)
                     /locus_tag="KRH82_002030"
     CDS             complement(5265..6185)
                     /locus_tag="KRH82_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBG8655309.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLDHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(6295..7209)
                     /gene="murQ"
                     /locus_tag="KRH82_002031"
     CDS             complement(6295..7209)
                     /gene="murQ"
                     /locus_tag="KRH82_002031"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBG8655310.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(7308..8405)
                     /locus_tag="KRH82_002032"
     CDS             complement(7308..8405)
                     /locus_tag="KRH82_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBG8655311.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKRINEYAKFKGFEVILDVNPRVFGELEISYKDLTFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLKH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(8638..9984)
                     /locus_tag="KRH82_002033"
     CDS             complement(8638..9984)
                     /locus_tag="KRH82_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8655312.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(10073..10381)
                     /locus_tag="KRH82_002034"
     CDS             complement(10073..10381)
                     /locus_tag="KRH82_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8655313.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(10643..11041)
                     /locus_tag="KRH82_002035"
     CDS             complement(10643..11041)
                     /locus_tag="KRH82_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655314.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKEMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(11043..12203)
                     /locus_tag="KRH82_002036"
     CDS             complement(11043..12203)
                     /locus_tag="KRH82_002036"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBG8655315.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREIFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(12634..13653)
                     /locus_tag="KRH82_002037"
     CDS             complement(12634..13653)
                     /locus_tag="KRH82_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655316.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNIEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(13647..14327)
                     /locus_tag="KRH82_002038"
     CDS             complement(13647..14327)
                     /locus_tag="KRH82_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655317.1"
                     /translation="MYRILLVEDDIDLSKEIALAFEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(14479..16386)
                     /locus_tag="KRH82_002039"
     CDS             complement(14479..16386)
                     /locus_tag="KRH82_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8655318.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AVLKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(16387..17139)
                     /locus_tag="KRH82_002040"
     CDS             complement(16387..17139)
                     /locus_tag="KRH82_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655319.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(17455..18609)
                     /locus_tag="KRH82_002041"
     CDS             complement(17455..18609)
                     /locus_tag="KRH82_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655320.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSVLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(18612..19079)
                     /locus_tag="KRH82_002042"
     CDS             complement(18612..19079)
                     /locus_tag="KRH82_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8655321.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(19093..19581)
                     /locus_tag="KRH82_002043"
     CDS             complement(19093..19581)
                     /locus_tag="KRH82_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655322.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIKQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(19595..20926)
                     /locus_tag="KRH82_002044"
     CDS             complement(19595..20926)
                     /locus_tag="KRH82_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBG8655323.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKVQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(20940..22505)
                     /locus_tag="KRH82_002045"
     CDS             complement(20940..22505)
                     /locus_tag="KRH82_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8655324.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(22674..23459)
                     /locus_tag="KRH82_002046"
     CDS             complement(22674..23459)
                     /locus_tag="KRH82_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8655325.1"
                     /translation="MRLEEMIFFNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(23626..24825)
                     /locus_tag="KRH82_002047"
     CDS             complement(23626..24825)
                     /locus_tag="KRH82_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBG8655326.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDRYWQGIVSK
                     LIKNDIKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(25348..26685)
                     /gene="xylA"
                     /locus_tag="KRH82_002048"
     CDS             complement(25348..26685)
                     /gene="xylA"
                     /locus_tag="KRH82_002048"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBG8655327.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(26781..28331)
                     /gene="xylB"
                     /locus_tag="KRH82_002049"
     CDS             complement(26781..28331)
                     /gene="xylB"
                     /locus_tag="KRH82_002049"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBG8655328.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            28539..29699
                     /locus_tag="KRH82_002050"
     CDS             28539..29699
                     /locus_tag="KRH82_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBG8655329.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDVGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(29855..30259)
                     /locus_tag="KRH82_002051"
     CDS             complement(29855..30259)
                     /locus_tag="KRH82_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655330.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(30280..30762)
                     /locus_tag="KRH82_002052"
     CDS             complement(30280..30762)
                     /locus_tag="KRH82_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8655331.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(30782..31591)
                     /locus_tag="KRH82_002053"
     CDS             complement(30782..31591)
                     /locus_tag="KRH82_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBG8655332.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(31584..32363)
                     /locus_tag="KRH82_002054"
     CDS             complement(31584..32363)
                     /locus_tag="KRH82_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8655333.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(32363..34441)
                     /locus_tag="KRH82_002055"
     CDS             complement(32363..34441)
                     /locus_tag="KRH82_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBG8655334.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(35240..35761)
                     /locus_tag="KRH82_002056"
     CDS             complement(35240..35761)
                     /locus_tag="KRH82_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBG8655335.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAIDLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIHHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            35927..36493
                     /locus_tag="KRH82_002057"
     CDS             35927..36493
                     /locus_tag="KRH82_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBG8655336.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(36710..>37869)
                     /locus_tag="KRH82_002058"
     CDS             complement(36710..>37869)
                     /locus_tag="KRH82_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBG8655337.1"
                     /translation="CTDDNDVNKVLKRINKLEIFVSYPFILELFDDYNEGIINKKVLV
                     ESLNLVECFILRRIVCDVPPNALNKVFMNLGREIKKFSDYKENYSNILRYIFINKKSS
                     QRFPTDSEFSNAFETKDIYNTKSKNKLYILERLENYNNKEIVDLENLINNNMLNIEHI
                     MPQTLTNKWKESLGDNYKEIHDKYLHTIGNLTLTGYNSKLSNKTFEEKKEMEDGFKDS
                     RLYLNKYISSIDKWNEEEIKNRTKILLDRAVEIWKYPSVTYEPPSNSENIFTLEDDDV
                     NFTNESIVSFSILGESYKAKNWTEFYEQVALTLYDLDSVRFNSIVDKTYKRDFIDNIK
                     SRDAYKLRKGIKISENIYLETNLNTEAKLNIIRFLLNEFDIELNEVIFSIK"
BASE COUNT        12467 a         6567 c         4029 g        14806 t
ORIGIN      
        1 attaatatac tttttaatca aatttaaaca gaataattat accaatatat aaaaaaattt
       61 ctaaaaaaca ataaaattaa gttataaaca ccaatatatt tctattattt caataagtat
      121 acaattagat tagaatctaa cgctagtaat aaaaaattac tttcccaaaa tagatataag
      181 cttcatttta tcgttcaaat aatgaaaata tatttgattt catgcaaaaa gagtgcctaa
      241 tgaactaaaa agttcatttt gagacactca tttttttata taaatttata tagtttttaa
      301 tcgttcgcat tcaaccactc agttaagact tttatatatt tctcattttc ttcaacgaat
      361 ggcatatgtc ttgaatactc aaataattcc cacttactat taggtattct atcatacata
      421 gtctttgcaa tatatggtga acataaatct attgctccac tagttactag acaaggctct
      481 tttatttcat gtaatctatc tgtaaattca tatccagaaa gagttcctgt aggagaaaat
      541 tcattttgtc cccatcctac aatatatgct tcagaacctg attttttagg tcttctcagg
      601 cactctggag aatcttctgt cacttcacct gcacaataca tttccataaa tctttctaat
      661 gcatcattat attctttgct agagtaatct ccagtattta ctgcatcaag taatgctttt
      721 tggtcaacct cactcatata tgatattctt cttttttgtt ctttctccca aagttttgca
      781 gaagaaagag tagatgaaag gatgtaagac ttaatacctt ttggtttata ttcaatagca
      841 taccaaatag cctgcatacc tccccaagat tgacctaaca gatgaatttc atcaagtcct
      901 agatgttttc ttagttcaat aagctcctct atccaagtat ctgcattaaa tagctcagga
      961 tgcccttcta caaatgaatt tccacaacca atttggtcat acattattac ttgtctacca
     1021 ctttcagcta tcttatccaa tacctcaaaa tagttgtgtg tagaacctgg acctccatga
     1081 agtaatacta atggcttctt cccttccgta ttttctccta ctatacggta atacgtttta
     1141 aaacctttaa aaggcatata tccttcagta attttcatgt ctatctcctc caatttgtaa
     1201 ttataaacaa taatcaagtt cattaacaat actatttaaa acctcttata catatttgat
     1261 tatgtatttt aatctttata cctactttta taaatagtat aacataaaag ttaaaaatct
     1321 ctatactaaa ccaattataa aattatatta actatataat tttatttttt aataatagta
     1381 tatacatatt tgattatttt catttgctgc ttaaaatcaa ttttaagttt tcttcctata
     1441 ataaacttcc tctttgtggt ctcatgttag tctctaaatt taaaatttta caaaaaattt
     1501 tcataaaata aaattatatt gattgtatct aaacaaatag ggcaataaaa taattaagta
     1561 tagttactta cctttcaagc aatattagtt ttatgttaga attttattat attgatttac
     1621 aggaggtttg catttgaata atattaattc acttaaagta ataaaattat ctcttggatg
     1681 ttctcttgct atatttattg cttggctatt aaaattagaa tattcaatgg ttgctggagt
     1741 tatagtacta cttacagtaa aggacactaa aagagaaact cttaaaggct ccattggaaa
     1801 gatttatggt tttcttttat gtactatttt ttcatattta tgttttaata ttttaggata
     1861 taatttgact tcattttcaa tatttatatt tataattata ccactttgtt ttttgttaaa
     1921 tattcaagat gttattgcta tgtgtgtagt catagcatcc cattactacc ttcaaggaga
     1981 aacttctatc aaatggattt taaatgaagc tggaatattt gcagtaggaa ctggaatagg
     2041 tgtcttaata aatatgtata ttccaacaaa tatacataaa atccatgaag ttcaaaaaaa
     2101 gttacaggaa gaagtgagta ttgtacttat agacattgca gatattattg taaatcctaa
     2161 aaaagaaaat ggatatagta gagatttata tacattaaat tcacttattg acagcagtat
     2221 ttctgaaact tacgataata ttaataatac tttattaagt gatactagat tcttcttaga
     2281 gcatatggat attataaaaa gtcaacggga tatcttagaa aatttgtata gttatgtatc
     2341 tcaactaaat tctacaccac cacaagctca tattctatct gcttttatac ataagatagg
     2401 ttatactgaa tttgaagctg aaacaggcaa tcttcttctt gaagaattaa agagactaat
     2461 gcttagtatg aaaaaccagc ctctacctgt tgacagaaca gagtttgaaa atagagctat
     2521 tttattccta tgcttgactg agttaaaaca gtttttagtt aatcgtaaac atgctcagat
     2581 gcttagagat aataattttt ataaataaaa aggggagaaa tctagcagtt gacctgacta
     2641 caaaatatca gatataatat taaatgcgcc cctagtaaga gggcgcaatg tttataactt
     2701 attctactgt catgattaaa tcattattca tatcgaacat acattatttg accaagtcca
     2761 atattagctt tttcatcagt gatttctatt ttaatagtca catcattttt tttacagtac
     2821 ttcgctaatt ctgcaccaga acgattttta ccactaaaat ctaaagaaaa tggcttatca
     2881 tatttaaaag gatattcaac aggtttaccc tctggtgcta atgcaaacat cccatatggt
     2941 gtgttcataa atcctattac agcaatcgta agatttgatg ggtctaaatt tgattcacta
     3001 cctgtaaatg taattgtatt tactgatgaa ttaactacac tacatctaac accttcatac
     3061 attacatgtt tttcatttat atcttctcct ttttttccaa aatttccaac agcctttgcc
     3121 ccttcttgat gtggtaacat agtgtgcttc ccaggtggtg ctggtttctg tgtctgttct
     3181 ggttttaccg tctgtactat tgcaccaact tttggatatg ctgtcttatc aaatggtaat
     3241 gggtggctaa gactcttgta tatgatatcc tttcctgctg atttattagc atcaatatct
     3301 acatgataca aacgcccatc accaaaacgg ataagattcc actggtggtc atttgatgtg
     3361 ctgtgtacat aataagattc aattcccata gcatcacaca aagctttcat gctcctagcc
     3421 attcctgagc atgcaccttt tttagtaacc aatgtatagg cagtatttgc tccctctact
     3481 gcattccagt caacatatgt tgtgttattt ttaatgtgat tgtaggcaac taaaatctta
     3541 gcatctgtgg tcatattctt tgtgattttc ttgttcataa aatctgctgt tgcttgtgct
     3601 actgagttta gttgggcttg tgacagcttt ggaccatata cgctattggt tccagtgaca
     3661 tagctttttg gtgcttttgc tgttacctct ttggctgtca taccataaac tgtcatactc
     3721 atacctgaga ttaaaactat tgttgtaatc aataacttgg tagctaactt cctaattttc
     3781 ttcatactta atattctcct ttataaaaca ttgttacttc ctattctcta ccattaataa
     3841 aattaattta ggatttaaaa aggtggattg tcaacatgta tatttctcca ttcatacatt
     3901 cgtgaaatat ttaaatttca tggaaaatct aatagatatt ttctagataa tttgtataca
     3961 atacaactcg caaatcaggg tgtttgctgt tagtttgaga aaatgatgat gattaataca
     4021 ttcggaatct ttgacctata ataaatacca ttgtcttcaa tcattaataa tggtaagagt
     4081 aaagagaatt atcaataata cagttaaaat caactttgta tacatttcat acattctctc
     4141 ccaacaacat tatacttctt ataatttgta tattcaatac gttttctggg aaaatatagg
     4201 atatatctat aaaaatataa aaaaggagtt gaacttaaaa tttgattaaa aaaaatcaat
     4261 tttaagacaa ctcatttgta ttataaaaat gctatatatt attattaagt aagtcaatat
     4321 tttagatatt tatctatttc ttattgactt acgcttatag cctaacttat ttgtttagtt
     4381 gatatataac ctagttttaa gcattattaa tatttaaata atcaagtatc ctttttgttt
     4441 cttgtagttt ctgttctgcc tcatttaagt tttcttgaat tatagaaata tatattatat
     4501 ctatcaacgt aagcattgct attcttgaag aaatagctcc ttctctaagt cttttttcta
     4561 tatttggtac tactagcttt aaatcactaa tcttactaag atgattgtca ctatatttag
     4621 ttatacaaat gaccttacat ccttttaatt ttgcattttc tatagacttt attacttctt
     4681 ttgattctcc agagtaagat attgctatag ctatatcttc tttatctaca tttgaagata
     4741 ccataagttg tgtatgacta tctaaagagg taaatgcctg tttatttatc cttaaaagtt
     4801 tcatctgtaa atctagtgca actaaagccg aaccacctac tccaaatata tatacatttt
     4861 tagcctttat tatctgttca actgcttctt ttattatatc tttttcattc aacaaccttg
     4921 tttggttgat agtctctatg tttttgtttg taattttgtt tataacacta tctatattac
     4981 aatcatagtt ttcatctaca tatgtgtatt cattttcttt gcccatcaaa tctttagcta
     5041 tctcaatttt taaatcccca aaacccgaat atcccatttt tctagaaaac ctaactatac
     5101 ttgctgtact tgtttttgag tttgacgcca attctgatac agaaagctta cttatagcct
     5161 ctgtattatt aagtatgtaa tcagctattt ttttatctac ttccgttaaa tcttcatata
     5221 tctgttttaa ttttaaaatg caactcatac tctaccacct ctacctattt actataatat
     5281 ttcttcttag caagtaaaca tgctcctaaa tctggagtca acactggtct cactatacca
     5341 aatctcgttt tattcaaata ttttttaagt ggctctaata ttaaatctcc tgacttaaac
     5401 actccacctg aataagatac ctttatcttt gtaccttgtt caaaatgatg atctaatcct
     5461 attataagcc tacttaattc ataagctgca tcatcaaata ttttactagc agtattatca
     5521 ccttcaataa ctgcttttaa acatatcgta gcaaactttg ctatttctat tctatctcct
     5581 tgtatttcat catttacata ttttattatg tcataatcat tctctatatt aagatgtctt
     5641 tttattaaat catataattt tgtttttgaa caccttccat cagactgcat tgtgaacatt
     5701 tttaaggtag ccattcctat ataatacgct gaaccttcat ctcctaatac atagccccat
     5761 cctccacatc tgtgaagatt cccatcttta tctaaagcct gtgctattga accagtacct
     5821 gcaattatat ttataccttt ttccccattt aaagaacctg ctaatgctat ttctacatca
     5881 ttacctagag tataatttat atgactatat gcattttttg ttgctacttc taatgcatac
     5941 aatacttctt ttatttttcc atatccagca agtccaacaa atgcatacgt tatttcttct
     6001 acatttatct tagcatcttt acaaacttct tccaacccag ttattaataa tttcgttaga
     6061 ttatcaaatc ctatttgatt ataatgacaa gttcctttgg ttatggttcc tactatattt
     6121 aattcttcat ctactaatgt aaatgttgtt ttcgttcctc caccatctac acctaaaaaa
     6181 tacatactat cctcctacaa tatctttaat aattctttca atacttaata tctaaaaata
     6241 accttccaat gctgtttttt taatattgaa aggttatcag tactattatt tattttacaa
     6301 tttttctatt gattttaaag cttcacttat ataaccttct tgtctatcta ggatactctt
     6361 tgcactatcc ttatctaaac cactttttat cataaatata gccaatttaa cgctattatc
     6421 tgcttcttct aagaattttt ctgcaacgtc atattttaca tttgtagcta tcattattat
     6481 tctttttgct ctttcaacca acttttcatt tgatgtctta acatctacca tcaagtttga
     6541 gtatactttt cccatcttaa ccatagaagc tgttgttaac atattacata ccattttttg
     6601 agctgtacca cttttcattc tagttgagcc cattattact tctgccccta ctataatgtt
     6661 tattggtaaa tccgcttttt tactcatttc actattcgga ttcatagtta ttgatagtac
     6721 tgcacacccc aattccttag catactccat tgcacctata acataaggag tccttcctga
     6781 tgcagctata ccacatataa catccttaga tgtaactcct ctatctatta tatcttgctt
     6841 tccaagttct ttatcatctt cagcaccttc tattgcttta aatattgctt gatttccacc
     6901 agctattata gcttgaacaa gctcaaaatc cactccgtaa gttggaggac attctgtggc
     6961 atctagtatt cctatcctcc cactggtacc tgctcctata tagaataatc tacctccctg
     7021 cttcattcta tctactatta tattaacagc ttttgctata ctctcctttt gttcttcaac
     7081 agcataggct acagttttat cttcgttatt tattaattct attatgccta atgtatcttc
     7141 tttatctatt tgcaatgtat tcttatttct accttctgta actaaatttt ctaaagtttt
     7201 tattaacata tcatttcctc attttcttaa tattaaattt ttaaacacat tttaattcca
     7261 actttcataa ttatattttt ataataaatt aatattttca taataaatta ttttgttgag
     7321 ggtttaaaat taaacttttg ccatggttta atataatcta atataaataa ttcttctttt
     7381 cttatatatc ctactacatt cgatttacca ctgtttttca tatcagtcaa ggctatttgt
     7441 aactcccctg cataatgacc atattcacta ctttcaatta ctatatctcc tctttttatt
     7501 attttaggag tattaaatag ttcaaatttg tatcctttat atttaacacg agattgagta
     7561 gaccttatca gactatcaga tatgtcccct ctattaaaat gtatttcttc aaagagtatc
     7621 ttcttctcaa cttctcgtat attttcctct attgctacat caaatgtaac catatctttt
     7681 ctcatagaac ctaatacctt tagctcctca tatgttggat aacaatttga tattattata
     7741 tcatttatat tattcatagc tattatatgc tttacttgaa tatctatagg tagatttctg
     7801 tgcatctcaa ttgttggaag cccatcagtt acaggccatg gtccaaatgt agtttcattt
     7861 tgacttgtta caaaaactgc tgttcttaat ccatacttat taaatctttc tgtacatttt
     7921 ataaagtgtt ttaaatttaa tccactatat ctatgtggat aaaagttatg acatcctatc
     7981 aaattttctt tatttggttg gtagtccatt attgtatcta tataattagt attattactc
     8041 atattgattt ctattttaag attttgagga ttaaaagtca ttaatgcctc ttcagaacct
     8101 gtaaatccca tatcaagcct tattccgtct gccttcgtct ttttaaaaaa agtcaaatct
     8161 ttgtagctta tttctaattc accaaatact ctgggattta catcaagtat tacctcaaaa
     8221 cctttaaact tagcgtattc atttatacgt ttaaattttt taattatatt ttctttagta
     8281 tctttaactg ataataaaca tgaaaatata cgtgtaaatc cattttcagc agctttatct
     8341 atataatcat atatttcctt agatgttgtt ttttctggat aaattgatat tcctaatctt
     8401 cccatctgtg tcatctcctt atatcctata tgtgtttaaa tttatttcga attacacgaa
     8461 acttttttaa aaatttggtg aaaaaaagtt tcatatatat ttataaaaaa agaaaagttt
     8521 accttttctt tttttataaa caatcaacaa aatatcttcg ttacttattt cataactgtt
     8581 atactttgaa atttatacta atctaatata gtttttaatt tccaatatag tttctaatta
     8641 ataagcttct tgctcttcaa ctttttcttc atgaagcaat ctcttatcgt acatcttgac
     8701 aaatggatag taaattatta ttgatatagc tatacataat aagttaagaa ctgaagctct
     8761 ccaatctcca ccagtggcta aatatgcccc tactggtcct ggtaatgtcc aaggagcagt
     8821 aactactact ctggatacta aattagcact catagcaaac catgaaactg ttgccattac
     8881 tattggtgct acaacaaatg gtattattaa tattgggttt aatactattg gtgctccaaa
     8941 tattattggt tcatttatat tgaatattgc tggtattaca gttgcttttc ctaaagactt
     9001 tccataagct gattttgctc taaatgcaag aagtaaagct aagcctattg tagctccaga
     9061 acctccaatc catataaacc attgaaaaaa gggttcagca gcaatacctg gaactgcttg
     9121 acccgcagca tatgaagctg tattagcatc taataattgt atccataaag gtcttgccaa
     9181 tgaacctatt attgatacac catgtattcc aaatgaccaa aaaaacgtta ttaaaaatat
     9241 tagtataatt actgatggta atgtgtcagt ggctgaaact aatggagtta ctaatttagc
     9301 tatgaagcca tgccaatcaa accctaggaa ataagtaaca atagccatta aaattattat
     9361 taatgcggct ggtgtcagag cttcaaaaga ccttgtgact gatgctggaa ctgcttctgg
     9421 catggttatc ttgaatttag atttgtcagt aaatctataa atctcaacac ctattataga
     9481 tgttacaata gcaacaaaca ttgaacctcc accaagatta gccattggca tttgccatcc
     9541 ttgaggaatt gaattatacc aagctaaaag ttctggactc ttttcaacta tctttaataa
     9601 atcaggggta agaccctcta ttgcagtagg aactattgtc aaaagaaatg tagctgtagc
     9661 taataaacct cctgtcaatc catctaactt atatgacttt gccaaactat aacctatgcc
     9721 aaatgtagaa tatactgata taataaaaaa tgtcattcta tatggtagta atattgtaac
     9781 tgcattttcc tttagatact gagttacccc ccatgaatct ggtaatggag gaaatgctaa
     9841 tatcaagaaa aatgacccaa ctattataag tggtaatgaa gctacgattc catctcttac
     9901 agctcttaag tgacgttgtt ctgccaatct ggccatagaa gttgataatt tagtgtctaa
     9961 aaattctgta aatttatcta gcatcttttc tctccttaat taatatttat ttttattatc
    10021 attaaaattt ttataaaatc aactttcttc taatctaaca acactgcaac tactatttac
    10081 tcaacagttc ttgaacttgt tttaataact ttggtcctcc taatggacta taagcttgtg
    10141 cttgtattaa tgcacatggt acactaacct catcagcaaa agcttttaaa tagtcaaatc
    10201 tatgtctgac ttgtggagct accatagcaa tatcccatcc atttttaact tcatcctcaa
    10261 actcttgagt accaacagcc aaaacatcta tatctattcc attttttgct ccttcttttt
    10321 gtaatgcatt aactgctata gcacttgaca tccctgatga acaaacaaat aatactctca
    10381 tattgattcc ccctgttttt ttatttcttt tcaatcatta tagcatgtat ttttgattac
    10441 aggaatacgt ttgtatatat tttttcatat tttacatttt tatttgtaat tttatttcat
    10501 gaatttatat cttgctttaa ttgctttatt tatctaatca ttcttttgtc taaaattaca
    10561 cactacttaa aatactcata tcttttctta aaaaagaaaa aagactatct tattattaac
    10621 ataaaatagt ctcaatactt ttttaaatat gtattccttt atatatccag aagtaaccta
    10681 ttattgcaaa tgataaagca aataaaatat acagtctaaa aaatcccaaa gaaaaacctc
    10741 tcttagtttc aacaaagtat cttgtatatg caactgcaaa agatgtaatt aatgaatttc
    10801 ctataacaac tccaaatcta ttatctattc caaatataga taataacaaa ggaaaaacta
    10861 cagtacttac aagagatgaa actattagta ttaatccact tttaaaactt atagttggaa
    10921 tattataatc tgttctttga tttttctcca tttctttctt agtattttta ttactttttg
    10981 tactttttgc atttttataa ttattatttt tctttctttt ctttttttta ttattagaca
    11041 tgtcatttac ctccaaaagg tttaggtgtt atattcccta aaataacttt atttttagcc
    11101 cctgttgcag atattacatt agaaaaagaa ttatttaatg tttcattgcc caagattaca
    11161 aatgccaaag cctcctttgc atcagaagaa tacccatatt catcttgagt taatacttca
    11221 acctctaata ataactcttt tatatatcct attaaagtta gattatgagc tcctccacct
    11281 ccaattaata aagtatctac attaaccttt ggaagtatga agtttttata attataatat
    11341 atagcttttg ccgtaaacat agttactgtt gctatcaaat catatttatc tacatgttta
    11401 tatttgttaa gcatgttatc caaatagact tgtccaaata tctctcttcc agtgctttta
    11461 ggtggcgctt gactaagata cttatgactc atcaaatctt ttaacatttc ttcattaatt
    11521 ttaccttttg atgcaaagta tccattttta tcatactttc tattaaataa tctttgacat
    11581 actccatcta ttatcatatt tcctggtcct gtatcaaatg caaatacatc atctatgtta
    11641 catgatttag gtattatagt aatatttcct attccaccaa tattttgaag tgctaaattt
    11701 ttattgttat cactatataa taaaaattca ctatatggta ctaatggagc accttctcca
    11761 cctgctgcta tatccattac tctaaaatta gatattacct ttgtatttgt ttcatatgct
    11821 ataactgctg gttcacctat ttgaagcgtt gaagatacaa aattattata acttcttggt
    11881 atatgaaaga ttgtttgacc atgagatgcg ataaaatcca aatttgctat atgaaagttt
    11941 gctttatgac acactgattt tacagcttta ctaaataaat atccaagctt aaaatttaag
    12001 ctacagatta aatcaacact cgattcctct tctatacagc actttcttat ttcgtctttt
    12061 atatctttag gaatttctag agttataaat tctatttgct taactttagt atttctacca
    12121 ttcccactaa tttcagctag tactgcatca actccatcta aggaagttcc tgacattaaa
    12181 cctacactat acatagttat catcctttta agtttatagt tattcctccc caaatcaagg
    12241 tattaagttt aataatttta gaattaatct tatttcatct ttaattacga taatttactc
    12301 ttatgaaatt aattgagtta atcttataca cgttttttac cttagctaaa tcttacatta
    12361 atttattttc agtgtcaatg taataccatg taattttttt tcacaaacaa aacatattct
    12421 ctctccaaaa accatattaa aatagttact acaaataaaa aacataccag gtacatatct
    12481 gatatgtttt tcatatataa taattattat tttataatat agatagagca tcatttaagg
    12541 cactaattaa atcttcacta ttttcaagaa ctaaatttat tcttattgta tatgtcgatt
    12601 tgtatatgat gatagatttt atagtctaat aacctaacta tctaggctta aataatctga
    12661 tatatcataa aaatagatat taaaaattgt atatgaacca ttttccgaac atacctcaat
    12721 ctcatgccct aaactatcta tcattttctt tacaaaatac atccccattc cagtagactt
    12781 atacaattga tttcttccat ttttccccgt aaatcccttg tcaaaaaccc tagatatatc
    12841 ttcctcattt atacctatac caaaatcttt tatagataat accactccat tttctaactt
    12901 ttttgaatta aattcaatct taccaacttc ctttgaatac tttatagcat tattaataat
    12961 ttggtctaaa acatatgaca tgcatttaga atctgtgtaa acatcatttt ctaattcatt
    13021 caaactaact tctatattat tttttataag caaaaatgaa ttatttttta tagacatttt
    13081 taccaatttt tctaaattaa atttatttat aaatacatct tcaaacatag tgttgcttct
    13141 actactatac aaaatagagt ttactaaaaa atttatcttt gcaacctgat tcttaatatc
    13201 caaactatct tctatgctac ttaacctatc tgtaattata cttaaagaag atattggaat
    13261 ttttatttca tgaacccatt tagctatgta ctcatccaat tcttttaatg attgtttata
    13321 agtctctatg tcactattat tttttatttt taagttttct ataatatctt ttattagatt
    13381 ttcttcaaaa gattgtccat caactaaata actgtctatt tcaccactat tttctataca
    13441 attatataaa tttgtgtaac tatttctaaa atttatataa tctataacaa aaaataccat
    13501 tattataaac agcactaaaa aatctaaata tattaactct gaatatttat ttttaaaaat
    13561 atctatagca aataagtaga tatttattat actaactaca actaaaggta gagcaatata
    13621 cttagaccta cctttcaaat attttactag cattgtatta tatatcctat ccccttctta
    13681 gtttttataa aatcatcaaa acctagttct ttaactttac ttctcaatct attcatattt
    13741 acagtaagtg cattgtctgt cacaaactca tcattatccc atagagtcat cataagactt
    13801 tcccttgata caaccctatt cttatttttt aataataatg ttaaaatttt tatttcgttt
    13861 ttagtcaact ctatactttt atccttatac ttatgtttta taatcccttt ccccacatca
    13921 aacatcaaat cttcacaata caaaatacta ttagaatcac tataattata gactcttctt
    13981 attataccat ttattttggt aaccaatatt tctatagaaa atggtttggt aatgtaatca
    14041 tctgctccat tatttatacc cattattaaa tccatatcag aatctcttga tgataaaaat
    14101 attaatggta catttgaaat agctcttatt ttttcgcacc agtaaaatcc attatataat
    14161 ggtaaattta catctaaaag tactacatct ggttttttat ctataaattc atctaatact
    14221 acctcaaaat catcaattaa ttctacttta aatccccatt tttcaaatgc taatgcaatc
    14281 tcttttgata aatcaatatc gtcctctact aataaaattc tatacatttg tatattctcc
    14341 attatcctaa tatttcacta tgctatgaat tattaatatc ataacatatt ttatatgaat
    14401 ttattaccca aattatttag ttaatcaaca aggagactct tattacaaga atctcctttc
    14461 tctttattaa tatatcaact aatttttata cactacactc ttaaacttat taacagatac
    14521 tgctccatat attatgaata ttatcaaaca tatcactaaa cttagtatat atataccaaa
    14581 taaatcggtc atcaataaat ctcctgctaa tctcaatgca aaataactag atatagttgc
    14641 acttaacatt ggcaaagtat aaaaaatagc tacttcttta agtacagctc tatttatatc
    14701 tttttctgta gtacctattt ttaacaaaat cttatatttc tctttatctt catatgcatc
    14761 actatatatt ttcatatata ttatacttcc agctacaatt gcaaagacta agaataaaaa
    14821 cacaagcact acatatgcaa acttcatcca ttgactctca ccttgagctt tatatccatt
    14881 ttgaatatac acatttttta aacttaaatt cttttcaata ttgttgaaca ttacttgact
    14941 attttcttct tgaaatacct ttgcaccata aaaatacact tgttgaccct tatctcttag
    15001 tttaaaatat gtatcatcat ttaccactat aatactttga ttaagtcctg tccctagtac
    15061 tggaactttt acttctcccc ttgaaatatt atataactga ccatcaagtt ttatcttggc
    15121 ttcttttgta gctattgatg ctatcgtttg agggcttttt aactctatta cattatttcc
    15181 actaactaat ctttcaccat actcttttaa ttctttatca ttgccattca ctttaagagt
    15241 attacaaaaa tcactatatt tcattatagt atctgttgta tcataagctt cttttatatc
    15301 tgttttcttt aaaattgtta gttctggatt tactgagtac tttatcttat tagtatcttt
    15361 tattatattc tctatttgtt ttttattcac ttcatcttta tccattgaaa ctatgctaat
    15421 agtgtacaca tttctttgtt cttgggcatt cttatgtata cgcttcatcg caactgaagc
    15481 accaagagtt gatattgttg tagttataat tatagctatt atagcataag ttttatagtt
    15541 tttatttaat cggtagttta tattgtttat tgcaattata ttatttccat taaataatat
    15601 ttttttattt ttgattataa tatcaaatat aacaggcata actgatttga ataatccata
    15661 agtacctact attattatac ctataacagg tagtacacta gttatatctc cagttcttat
    15721 attggtagaa agatagtagc catatcctat tactataatt gatactatag ctaatatata
    15781 tatacctatt cctacctttg gtattttttc ttgtttttta gatatattga ttagatttat
    15841 tacactactt ctacatattg ttataaaacc ttttacagcc attattataa atatagaaat
    15901 aaagattaaa gtagcatata gtatagcttc tatactaagt ccattagata cctttatatt
    15961 aaatccagat aactttatta tcactacttg aaaaaatcta gatgttatta tccctataat
    16021 tattcctgtt atacaagaac ttattcctat aagcatattt tctacaaaat atatttttcc
    16081 tatagtatat aaatctaatc ccataaaaga caatattcca atttctttag acctattctt
    16141 aaaaaatata tttgttgcat accatataaa gaaaaataaa aatactgata gtatcattat
    16201 tacagctact aacactgata gtgtaaattt tttattttca tcttgtaaca catttatagc
    16261 atcaccatat cttaataatt caaaattagt tagcacaact actgaaaaaa ccatagatat
    16321 aaaaaatgct agataagttc ttatgttact cttaaaatta ttataagcaa ttccaagtat
    16381 actcacttac atctcacctc ccatagaggc tagcatatcc ataatttttc cataaaattc
    16441 ttttctacta tttcctttgt ttaatttaca ctttatattt ccatcattta tcatatatac
    16501 ttcatttgaa taacttgctg ttagagggtc atgtgtaatc attataatag tagcgttatt
    16561 ttctctgttt attttttcta atgattctaa aagttcatat gctgatttag agtctaaagc
    16621 accagttggc tcatcagcaa atatgactgt tggatttgta attaatgacc tagctgctgc
    16681 gcctctttgt ttttgtcctc ctgataactg atatggatat ttatctaaat gattttctaa
    16741 tccaaatttt ttagctatag aaaatacctt agcttctatc tccttacttt tcttttttcc
    16801 taatgctaga ggaagtgcta tattgtccat tagtttcata ttgtctaata gattatagtc
    16861 ttgaaatata aaccctattt tttctcttct taattttgat agttcattat tttttacttt
    16921 tgatatatta attccatcta gtattatttc tcctgaagtt tgtttgtcaa gtgtagacat
    16981 taaatttagc aatgttgtct ttcctgcacc agatggaccc attattgata taaaatcacc
    17041 ttcattgact gtaagagata tattttttaa tacatttgtt ttaaatcctt ttattccata
    17101 atcttttgat atatttttta tttttaatat ttctttcata ataatagcct ccagttgcta
    17161 attttttaat atatatttat tttaaaggtt ttatataaat aaatccttaa gtaaatatta
    17221 cattttaact gttagcatta cacttttgta acatatggaa gactattata attataatgg
    17281 aaatatctta aaataaaagc atgatttact tctttgtata aacaaagaaa agaagctcct
    17341 aagaagcctc taatctatac aattattctt ctctataaaa aaccaaaata cacattgatt
    17401 gtggcaaata cagatactat aaacaagtga tattactact atatattaaa acaattattc
    17461 ctgaagataa ttcaataaga ctatcaagca ataagctaag catccaaaaa gacttaatac
    17521 cattaatgta taattatacc caatattaat gcttaaaaaa ccagcaacag ttggaataat
    17581 cagagatgaa cctcccataa atatacttaa agctattaat tggctactac ttctaagttt
    17641 tttaggagaa acttcaaata ttaatctttt tgaagtaatt aaaattaaag gagtagaaaa
    17701 cacttgaaaa acacacagta taataatgat atttgaatca tttgttaaag caaatagtag
    17761 aaactgaact gttatcataa tagcacttaa ttttaataag tttaaactgc tatatttttt
    17821 taataaataa gaaccagcca gatatgttgg tatctctaac actgactgta aagaccactt
    17881 taaagatatc tgagaatttg tagcatttaa agctatcatt ttatctatta cagtacagtt
    17941 atttgctacc accattgagt ataataagaa taaaatacat actagtaaga tatatttttt
    18001 atcttttaat aattcaataa tatctttatt agttacattt attttcttat taatcttttc
    18061 aatatcaggt aataatagta tatttataat aagtaatact acaattaaac caatcgctac
    18121 agataatcca aaatatgaga atctaagaat caagtaagat gctaccatac ttccaatagc
    18181 ccatccaatc gacccaaaag tcttaataaa tgacaaataa ttattaatat tatctccaca
    18241 acctattatc catgtatcat ataaactaca gcaagtattt aataatcctc ctgataaagc
    18301 aacaagtaat aagtatatta taaaagttgc agattcagta gaaaacataa taactgatgc
    18361 aattccataa actgataaac taattaaaac aatttttttc attgtttgat acttatcagc
    18421 taatactcca aataataatt gaaacaatat attggttatt gcatagctcg ataatataat
    18481 tcctctttca aacgctgagt aacctaattt tgataagaaa ggtgtgaatt ttgttgaagc
    18541 aaaggcaaaa ataatatatg agaaaaaata gaatatgata aatttaaatt taatcgcttt
    18601 attaatcata atcaatcaaa attgataact ttaataccac tatttccttc ctgatttaag
    18661 tttgaaagat gatattttac cgtattagga ttctctacaa taactaaagg aatatataaa
    18721 gtattttcaa gtaacttatt atcaatttct actaactttt cccccatatt aacttcttga
    18781 ccttgtttaa cttctaattt aaagttttct ttttttgttg ttgcactatc caatccaata
    18841 tgaataagaa tttgaacatc attttgcaat ttaattccta tagcatggtt agtttgagca
    18901 ataaaactta ttactccttt agtcggtgat ttaagaatat tgtcctttgc tatcatagca
    18961 aatccatctc ccattacctt agttgaaaat actttatcag gaatttctcc aagattaatt
    19021 atttttccat caatgtagga attaattgta attgcttctt tttttctttt aaagaacatt
    19081 atagacactc ctctacataa ttaactttat tctaattatc attacaaata acgatattaa
    19141 gcatactgca attgaggaaa aaagagcctt atagctcttt ccccattgta gttctttaat
    19201 actgcttatg atttgtttaa ttccaacaaa tttataaata taggtaaaca tgataacaat
    19261 agttattgtg taaatttgga atatctgccc taataagact aaatagaaag caatcatgtt
    19321 ttcttttatc tctttattct tttttatatt gtaaataaca tatgcactgt atactgcact
    19381 aaagttagag attaaattta aacttgcatt aacatcattg tttaaaagtt gtgaaaatga
    19441 aatatttgta aataatgatg tcaattctaa atacactata tataaaacag gtaatattag
    19501 aaaacaaacc ataaccactg aaagaaatat attttcatct tttaatactg ctgtgatatt
    19561 ttttatttta tttgttatca tgtttttgtt ctccttattt aaaagttggc cagaaatcct
    19621 tattagccac aatcatttca tctaagattt cttttgctac ttttgcactt ggaacagttt
    19681 tactcatagt aaacgactgc cataattttt gataactttt ttctatccat gcttctacag
    19741 ctaatttttc agaagcaact tgttgttcca ttaaaccttt ttggaaagtt ggaattttac
    19801 ctatagacat aggttcaacc atatcttttc caacaaggca aggaatttca accattgcat
    19861 catctgcaaa attttcaata gctccattat taggaacaat cagtaaaaat ctttcctgag
    19921 tattaaatgc taatgcacaa gctaattcaa caataaattg agaatgttca cttgcatcaa
    19981 accatgtatc tcttgctgtg ccatttttta taattctttc acattcttcg aatgtatcct
    20041 tttctcttct atccataatt tcatttgctc ttgtataatt tggattagca tgttcaacag
    20101 tttcatcagc cattaaataa tattttaaat aagtattagg taatgtagtc ggttctattt
    20161 ccaataaatc ctttgctgct ctcatagttt ctaaccaact agattctttg tgttgacctt
    20221 gaggtgtaaa ttcctcatat ccttttttag cacaatattc ttgtacttta ggcattaaat
    20281 catttccttc tttgtcctta atacttgtcc accacccgaa atgattcaat ccataatatc
    20341 taacatcaaa gtctttacga gaatttaaac ctaaaactct agcaaatatt tcctctaaac
    20401 atactggcat atcacaaata ttaataattc ttgaatttgg tcttaataca cgacatgctt
    20461 ctgcaactat agctgctgga tttgaataat taagcatcca agcatttgga gaatattttt
    20521 ccatataatc aatcatttcg attattggac ctattgttct taatccatag gcaattccac
    20581 ctgccccaca agtttcttga ccaacaaccc catattttag tggaattttt tcatcttgtt
    20641 cacgtaaagc atataaacca acacgaattt gtgccattac aaaatcaata tcagtaaatg
    20701 cttcttctgg atttgttgta taactaaatt taatttctgg atttttctct ctaacaatta
    20761 ttgcacatgc ttcagcaact tttctttgtc tctcatcatt attgtcatat aatttaattg
    20821 attcaatagg aaatttagca acactttcaa ttaacattgt tacaattcca gcagtataag
    20881 tactaccccc accagcaatt agtatcctct gtctttttct ttccatcttt ccttctcctt
    20941 tataataaat tttcaaattc ttctcttaca cttggtactg aaagcccaat aataatctga
    21001 atagcttttc cattatgcac taaaccatgt gcacctactg ccttaaaatc ttcttcttta
    21061 gaaataattg agtcatcttt caaggttaat ctcaatctcg tagcacagtt tgtaacatct
    21121 acaacatttt ctgctccacc aactaatttt atgtattcag atgcttgttg agaggcttta
    21181 ctcaatttat ttcctttttc atctttagtt tctaaatatt catttttagt atatagtttt
    21241 gtttcttcac tatcttcctc tctaccagga gttttcatat caaacttctt aattaagaaa
    21301 gtaaatacaa agaaccagat aaatgaaaat ataatcccta caacaacttg aacaacatat
    21361 accttccagt gatacattcc aagaggaagc caatttaata caacccagtt aataattcct
    21421 ccaccaaaat caccaacaac tcctagggca aacgaaatcg tttgcaagca tgcatctaaa
    21481 aatgcatgta ctaggaataa aagtggtgct acaaataaaa atgtaaattc taacggctca
    21541 gtaattccag ttaatactgc agtaagagta gcaggaatca ttaaacctaa tacttttttc
    21601 tttttttctg gctttgcagt tacatagaaa gcaccaaata cacctaatga accaaacacc
    21661 ttcgataatc cggataatga aaatccgatt ggatacattt cctttagagt cttagctgaa
    21721 gtttgaaagt cctgaatatg agtagcccaa tatactgatg taccacctgg aacaacaaca
    21781 ctatcataac aaattggtgc atatacaaaa tgatgtaatc cagttggtat taaaatcttt
    21841 tgtaagaatg cataacacca aactcctata tttccactat ttataaaaaa cgtttgcaaa
    21901 tgtctaataa cattttgaat atgaggccaa ataaaacaag ttaataatgc aactggtatc
    21961 ataacaaaga aacaaattgc aactacaagt gatgagcctc taaataatcc aataaaatct
    22021 ggcagttctt tatcataaaa tctattatga atataaatga caatacctga tattaacaaa
    22081 gcaccaacca taccagtatc taatgtttta ataccagcaa tgcttacaag tccacttcca
    22141 gcacttattt cagctgcgaa atcaactcca aagctttttc cccaaaaact taacatagaa
    22201 cctacaaaat aattaaaagt caaatacgtt gctaaagcct ccatacaagc tcttgcttgt
    22261 tgcttttttg caagtgctat tggtaaagaa atagcaaata ataatggtaa ttgattaaat
    22321 accatccaag ctccactaga tattacaccc caaaattggt accaaatatt ttctggtgta
    22381 gcaagtgaac ccataattga ctgattttga aatacaattg agaatccaac cattatccca
    22441 gcaaaagcaa ataatagtgt tggtgtaaac attgcccctc caaaacgttg tattttcttc
    22501 atcatataaa ttactcccct cctcatattt ttagtttatc tttggcctta gatatctatt
    22561 attttaacag gttaataaat atatacaatc tttagggtat attcggagct tattcacagt
    22621 caaataagtt tttgcacatt tttatgttca aattctcata aaaaaaagaa tgactacaat
    22681 ttgcaatcaa tcccttctgt aatcattcta tgccttttat aaatactata tttaataaat
    22741 aataactcaa tcaatataaa atataacatt gtcaatttat aactagggtg catttgtaaa
    22801 aatgagatat tagtcgctga aatataaatt gattcatcac ttaaatcagt caatgtatta
    22861 tttttaaact ctgtaattga aattatttta gttcctatta attttaatct tctagcaata
    22921 ttaagtgtat tctcattctc accacttagg gatataataa tcataacatc atttttactg
    22981 acaatattgt aaaaagaatc atcaaatgtt cttccctcaa aatcatatat tatttcttga
    23041 catgataaga acattctctt tatctgtttt gcaaccacat tttgaatatc acctgaacca
    23101 taagcgtata ttgttcttga ttcataaaga agtttacaca atgcatcata atctttattt
    23161 ttttgatctt caacatactt aattattgaa ttacatgcaa tatcaaatga ctgattttct
    23221 atgacatgaa ccttttctga ttcccagctt aataatactt taaactcact gaaacctttt
    23281 aaatctaatt ttttaacaaa tcttgtaata gttgcacgag acacattaca tttcatagca
    23341 agttcattta ttgacatctt actacaatgt tttttatttg cagttatata tttccatatt
    23401 aataaatctg tatcattcaa tttattataa ttaaaaaaaa tcatttcttc taatctcata
    23461 aactattacc ccctttaatt aaaaatcgtc ataaatatta taccaatatt caacattaaa
    23521 ttacagcgta ttcttatatt tactatttag cccataaaat tgactataaa aaatactgct
    23581 ataattgatg tttaaaaaaa tgtagtttta attttattct tttatctaat aattaatatt
    23641 ttcaagttct agtgcttttc ttatacaatt atcatcttta aaatcagcag tccttttaca
    23701 atcttttact ttaaattctg gaatagtttt aaattcctca tcacatattc cattcttatt
    23761 taaatacata caacttgcca ttctaactat tagaccacta ttttttaaat taaacaatac
    23821 agggtctata caccctccat ctccgccagt agtttcacca actaaagtcg caaatttatt
    23881 ttctttacaa aacattgcaa acgactctga tgatgaatat atttttctat caacaagtaa
    23941 gtatatatta cccttaaatt ttgaatcatc tgtagatttt atagtatagg aagtatcttc
    24001 aaaatcatta aaatctttta taatttcttt aggtgcattt tcctttacac ttgctggtaa
    24061 attttctaca ggatttaatt ttatatttct tgcatttgta tattttttta ctatttcatt
    24121 attatttcta taaattctat aaccatttat tttgatatca ttttttatga gtttagatac
    24181 gattccctgc caatacctat cacttccacc taaattacct cttatatcaa taattaaagc
    24241 tttatgtttt tctaaagtgt taatataatc tccaattatt tttaaatcat tatttataga
    24301 gccattcttt gatgacattg atggtaaata catatatcca atctgaccct taataacatc
    24361 ctttaaaatt aattcttttt ttacaaaaat atcatctggc atttttattt taagattcat
    24421 agagtcatat ctatccacaa cttttttatc attaagaaaa tcataccaat cattattaga
    24481 gtatgatttc ttaaaaagtt catatctttt cttattatct attacttctg tgtgtttatt
    24541 atttaaatca gataatatag atgacagttc ttctataaat tcttcatcat tttcagtgtt
    24601 ttttattcgt tttgtatatt catccttatt tgctaaccaa tcaatattat taagcctctt
    24661 atttacacct agatatggat atcctgtctt tacaacatta tacacataat taaagtcatc
    24721 caccttttcc tcttcagaca actgattctt ttgagaataa gtagaattac ctaataagat
    24781 tataaatgct aaaataatta ctaaaaataa tactttcttt ttcatgtaat tctcatccac
    24841 tttcagattt tatattttaa tacattgtat cattatttta ttatcaccta aacagttaaa
    24901 agaaattctt gaagatatat tccactatta ttctatttaa aaatttttat ttgtattttc
    24961 aaaattattt catgaaagtt ataaaataac aattatattc aaatatctat tttactgcta
    25021 tatcctgaaa gtaaattctt atcagtgata tactaaaaaa gatatgctaa aaaatttatc
    25081 cattataatg acttaaattt agatacttta ctgattttta tttattagtt gagaaagata
    25141 ttgataatta aaaatattga taactataga aatgattatt ttttatagaa attttaagga
    25201 tataaactaa ttatacttaa gtctatatcc ttaatttatc atgattatga gaatttttac
    25261 aaatacttat ctttgtccgt tttagaataa aaacaagaac atatcctact tattttattc
    25321 aaaaatccaa gtttaattac tacacaatta cttattagaa attgtatcta cttcatatat
    25381 atatctgtta agtatagctt ctagcatttc ttgtcttcca gacttattct ttataactgg
    25441 catttgcagt gcataagatt ctaactcttt aaatccaacc ttaccttcta ctatatcctt
    25501 acctatacct tcactaaaac ttgcatatct ttctttagta aagttttcaa atacctcatc
    25561 ttctaataat ttatgagcta ttaataatcc ctttgcaaat gtatccattc ctgcaatata
    25621 agctaggaat aagtcttcta cctcaaaaga tgctcttctt actttagagt caaagttaaa
    25681 tcctcctggt gctattccac cttgctttaa cacttcatac atagcaagtg ttgcatcata
    25741 tatatttgtt ggaaattggt ctgtatccca acctaataat aggtctcctt gatttgcatc
    25801 tatactacct aaaacattgt ttattcttgc tatatttaat tcatgttgga aagtatgtcc
    25861 tgcaagtgtt gcatggtttg cttctatatt cattttgaag tatttatcca gattatactt
    25921 tcttaaaaat cctaaaacag tagcagtatc aaaatcgtat tgatgtttag taggctcttt
    25981 tggcttaggc tctattaaga attggccagt gaatcctatt tccttagcat aatctacagc
    26041 catttgtaag aatcttgcaa agttatccat ttcaagttct gtattagtgt taagtaaagt
    26101 ttcataacct tctcttccac cccagaatac aaaattttct cctcctaagt acttagttat
    26161 ttccatagct tttttaacct gagctgctgc atatgcatat acatctgcat tacatgttgt
    26221 agatgcacca tgaacaaatc ttggatttcc aaacatattg gcagttcccc ataataactt
    26281 tatacctgtc ttttccatat taacttttat atactcaact atttcatcta atatcttatt
    26341 tgtctcttct aaatctcttc cttctggtgc tatatctctg tcatgaaaac agaaatactc
    26401 aattcccatc ttagacataa attcaaatcc tgcatcaact ttaatctttg ctatctcaat
    26461 tgggtctgtt atattattcc aaggtctctc tactgtccct actccaaatg ggtcattacc
    26521 ctctccacat aaagtatgcc aatagctcat tgcaaatctt aagtgttctt tcatagtctt
    26581 attacctacc acttgttcag gattgtagta tctaaatgct aattcattgt cagattttac
    26641 tccttcaaat tttatctgtc ctattccttt aaatatttca ctcatttcat gtcctcctaa
    26701 tattttacac atataatata tgtagtatgt tttcttaatt taaaactatt ttctatcttt
    26761 atttttcttt ttaagctaat ttaattattt atttttgcat taactacttc atctaataac
    26821 ttaaagtcat ctttcaaaga tttgtatatt cttttataca atctatgata tatattgtat
    26881 gtatctacat tttcacttat tggttctaat ttagttgaag tttttattat agcatcacat
    26941 gctttttgta tattttcata tattccagct cctactaatg caagaattgc aactccaagt
    27001 gctggtcctt cacttgaatt tatagtatat acatcttgat taaacatatc tgcttgcatc
    27061 tgtctccata ctttactttt tccacctcca cctgaggctc ttacttcatt aacgtctata
    27121 ttaagattct ctattatatc catacagtct ttaagactat atgaaacacc ttccattatt
    27181 gaccttgcga tttctttttt agaatggatt ggagataatc caaagaacac acctcttgca
    27241 taagggtcaa gatgaggggt tctttctccc atcatatatg gtaagtaaag caatccatta
    27301 catcctgttg gtacttgact tacttgatta tttataatct catatacatc ttcacctaaa
    27361 gaatttgaaa cttccacttc actttgacag aaattatctt taaaccattt taatgacaat
    27421 ccagctcctt gagtaactcc cataacatgc catgtatttg gtattgcatg acagaaagta
    27481 tgaactctac cttctttatc aatttttggc tcttttgtat aagcaaatac tacacctgat
    27541 gtacctatag tagatgaaac tactccatct ttaactattc catttcctat agctcctgct
    27601 gcttggtctc cagctcctcc taccactatt gttccttctt taagccctgt caaacttgct
    27661 acatctctag tcacataacc tgtaatctct tgtgattcat aaactttacc taaaagattt
    27721 ttatctatat ttaacttttc tagtacttca tcgctccaat ctctttttct tatatcgagc
    27781 aactgcatac cacttgcatc tgatacctct gtagcatatt cacctgtcaa tttgtatctt
    27841 atataatctt ttggaagaag tattttatta gtatttttat atatatctgg ttcattgttt
    27901 ctaacccata atatctttga tgctgtaaat cctgtaagtg ctggattagc agttatttca
    27961 atcagtcttt cttcacctac taaatcagtt atctcctcac actcttttac tgttcgttgg
    28021 tcacaccata ttatagagtt tctcaatgtt ttaccttcat tgtccagcat aactagacca
    28081 tgcatctgtc ctgataatcc aattcctttt atacattcac tgcttatatt tgaactttga
    28141 actacttctc ttatagattc gactacagct ttccaccaat catttgcatc ctgctctgcc
    28201 caacctgatt tctcttgtat aagaggatat tcatatgtac aactttttat agtatttcct
    28261 agtttatcaa ataaaactgt tttagtacct gatgtaccaa tatccacacc taatacatac
    28321 tccaacttca tccctccttg aatgccactt cataactatc gttttcctat cctaattttt
    28381 ttatatttta ggtatatttt acttgcttta tttttgttag tatattaaac taacttatga
    28441 actaataata aaatatttaa ttatctttgt caatgcaaaa taacctttta tttttgtgta
    28501 aaaagtatta caatattatt ttaaggagga atatcaaatt ggttactgat aaatacacta
    28561 ttcgagaaat gaatgaaaga ttggtacttg aacaaattat aaaaaatggt cctatttcta
    28621 gggcaagtat agcttctact ataggattga ataaagcaac tatatccgct attaccaaaa
    28681 aacttattga tgaatctcta gttcatgaaa taggaattgg aaatagtact catagtggcg
    28741 gaagaaaacc catattatta gtatttaata aatgtgcagg gatttcttta agtatggacg
    28801 ttggatacga ctatatattt tcttctctat cttacttaga tggaactatt ataaattcta
    28861 agaaattaac agatatacaa gtaagtaaag acaatgttat acaattgata gatgaaatta
    28921 taaatagtta taacatatcc aaaatagaca ctccttataa ggtaattggt cttactttgg
    28981 ctatacatgg gattacttgt gaaaataaag tattgtttac tccatattac aatcttaatg
    29041 agattgactt atatagcatc cttagcaaaa agtatgactt tcctattcat atagaaaatg
    29101 aagcaaactt aacagcttta gctgagaata ctttttcaac tgtacataac tcactactta
    29161 gtctcagtat tcacagtgga tttggttcag gcattataat aaataataaa ttatatagtg
    29221 gcagaaatgg tatgagtgga gaaattggtc acactatcat catgcctaat ggtaaactat
    29281 gtccttgtgg aaatcgtggc tgtttagaac agtattgttc agaaaaaaag gtatttgaac
    29341 agctttcttc tttagaaaat attcctaaaa tagattctga tatagtaaag caactatatt
    29401 atgaagataa ccagaatgcc aaaaaagtta ttcatgagtt ttgtagttac ttaacaatag
    29461 ctataaataa tgctattaca acttatgctc ctgaaataat atatttaaat agccaaataa
    29521 ttagtgatat ccctgagata ttacagatta caaaagatat gttagttagc tcttttaaca
    29581 aaggaataaa tatagaaatt tcatcattag ggtctgaggc atctctatat ggtggctctg
    29641 ccgtaaatat caagagcttt ttgaatatac aaaatttaac tttaattaat gaaatataag
    29701 ggttatgact atatacagcc ataacccttt aaattataca ttctaaaatt agatttatta
    29761 tatagtttat gcaagattag ctatattttt taaaaattgt atatcaatta aatattaaca
    29821 taagtatttc gttttaaata ttaatataat cttcctactc atcatcagat aataaacttg
    29881 cattttgttc aaccatagaa atattatctt tacctatttt ctctaatttt gctgccaatt
    29941 cctttgtatc taaaaaagct gattcaataa ccatacctaa atttagccct gaaataattt
    30001 taattcgact gtcattattg gctactaata aagcagcatt acatggagtt ccacctagta
    30061 aatctgccat tataattatt tctgaacttt ccttgtacac ttctaaagct ttttttaatt
    30121 tttctattgt tccttctatt ccatcatctt gtttcatatt tacagtagga taatctatag
    30181 aatcccctat tatcattttt gcagaattta agacttcttc agccatattg ccatgactca
    30241 tcaaaataat actattcaat ttaatacacc tctttaaatc tataagatgt ctacaagata
    30301 agttttctta tcatcaggcg tcattatagt tgtaatttca attccttcat ctaaaagtct
    30361 tttaaatgct tctttctctt cttcagtaac actgatatta ggtcttagaa ctgttgtatc
    30421 ttttctactt gacatatttc ctacatttat attatgtatt ttaaatcctg cctctacaaa
    30481 tggaataagg tccacaggag acttaacaat taataataca ttttgtcctt catactttcc
    30541 tgcagtaata ttttttatag cagtctcttc tgtaattata gatgacgcta tacctgcagg
    30601 tgtagccatt cttaaaactt gtttttgaac agaattgtta gctactgcat catttactac
    30661 cattaatctt gtaacaccca atttattact ccacatagtt gcaacttgac catggattaa
    30721 acggtcatct atacgaatat ttttaatacc tttcatttcc atatctaata tcatcctttc
    30781 cttattttaa aatacctaat gcatataaaa ttattgaaac aaccattact cctaaaatta
    30841 agtatatagg ttttatattc tttttaagag cccaataaac aatcacaact agaattgcag
    30901 gaactaaccc aggcataatt tggtctaata tttcttgacc tttcattgta aaatcacctt
    30961 gttgaaagtt caaagcaaca ttagctttta caactgaagg tattaatgca cctacaacca
    31021 ttaaacctaa aatagatgta ctctcagtta aaatctttaa acttttttca attgaagata
    31081 ttagcttagt acctgatgta taaccagcat taaatagtgg tatacttaat aatttcaatg
    31141 ctacactcac tacaatccac agtaagattc caaacggact tccatctatc gccatattag
    31201 ctgctatagc tccaaaaatt gtccacggaa taacgacaaa taaactatct cctaaacctg
    31261 ctactggtcc catcaagcct gttttaattg aagcaacagc ctcttcagtc tcttcacttg
    31321 ataactcctc cattgctaca ttaataccca aaatataagg ggcaacccaa ggattagtgt
    31381 taaaaaattg taaatgattt aatacagcac tttgtaactt ttctggatta tctttgtata
    31441 ctacttttaa aaaaggtagt actgcataac agtatgccaa ggcctgcatc ttctcataat
    31501 ttgaagaaac agaactagta aaaaaccagc gccataagac actttttttc accttttcat
    31561 ttgatttatt taatgatacc ttatcactca tcttcgtcca tacctcctac tacagtatat
    31621 tgttgttctt gattttccaa attctttttg taaattataa gtgcaattgc tccaccaatt
    31681 aaagctacac ctaataatgg tactttcata tatactgcta aaacaaaacc aattactaag
    31741 taactaaaat actccttagc aggaagatat ctaagtaata atcctatccc tactgctgga
    31801 agtagtcctc cagctactgt taaaccacct gttaaccatt caggtgtata tttcaaaatg
    31861 gtattaatta aagaaggtcc aaatattaca gatagagcaa ctggaatacc tgttgtagct
    31921 gctgttaata gtactcctaa catttgcata taggttatat ttttataatt tcctttttta
    31981 gctccatctt ctgctttatg aactagccat ataccaatag tatttctaag aacatctaat
    32041 tgtaccatca ataaagcaac tggaatacct atagagattc ctacagatgc ttcttgctta
    32101 gtcgtaatag ttataaatgt ggctactata cttgctgttt gataatcagg tattgatgct
    32161 ccaccaaagt tactaatacc taatgataat agctgtaatg tacctccaat atataatcct
    32221 gtatttatat ctcctaagat aagaccagta ataaaacctg ctgttactgg ttgatatgtt
    32281 ccaaacattg ttgaattttt ttcatagttt ataaaaaatc catatagtac gattaataat
    32341 aattgccata attgtggctc cattatgatt tcacctctcc caaaatattt tttagttctt
    32401 taaaattata actggaatct tgctttagga aaataggaat ttcttccagt gggcattcaa
    32461 cttcataagt tttcccacct tcataactaa ctccactaaa tatattttcc catgtatgtc
    32521 cttttggtaa atatactttt ctacttctat ctttataatt cattattgga gctactaaaa
    32581 tttcatctcc aagcatatat gtattatcca cctcccaagt tttatcatct tcaggaaatt
    32641 cataaaataa agttctcata actggtgttc catcttcatg tgcttctttc atcagttttt
    32701 ttaaataagt ttttaagctc tctctaattt ttatgaattt tgtaagaatt acttcaactt
    32761 cttcaccata agaccatatt tcattaggag ctccagttac cattgagcct ccacctttat
    32821 ttgataatgg tttactatga ggcaatctat ctccatgcat tctcaaaatt ggtgaaaaag
    32881 tagcatattg gaaccatctt accataagtt ctctaaattc tgggtcttta ggatttcctc
    32941 catggaaacc tccaatatca gtagtccacc atggtatacc tgccagtccc atatttaacc
    33001 ctgtatttac ttgattatta aaagcttcaa aactagaatc aatgtcacca gaccatacta
    33061 aagctccata cttttgagct cctgcccaag ctcctcttac aagagttaca acagactcta
    33121 tgtcattatg taaaccatca taaatcattt ttaaataatc aataggataa atattaccac
    33181 aacttaaaac atttcctttt ttatatctat agttatcaaa atcatacaca gaatagccag
    33241 gttcagctac atctaaccaa taatagtcaa tcccaagttg tttataattt ttatctattc
    33301 tatcccaaac atattctctt gcattttcat ttgtcatatc tacaaagact gtatttcctt
    33361 gaatttgcat tgtcattcta acaccacgat taacattgac taaatagcca ttttctaaat
    33421 aatcattgta gttttctgca tcactttgaa ctgtaggcca tacagatact attggttcta
    33481 ctgaatactc ttctttcaat tttttaacta attctttagg atttttccaa taatctaagt
    33541 caaatttata ttcaccttgc ttaggccaat gaaaatagtc aattgcaatt gatgaaagct
    33601 taattcctct tttagaatat tccttcacaa catctaaaac ttcttctgaa gttctatatc
    33661 ttagtttact ttgccatagt cctaaaaggt tttcaggcat cataggaaca gttccagtaa
    33721 cttgagagta atttttattt aactcttttg ggctttctcc acaagtaatc caataatcta
    33781 taaaatttgt agaaaacatc ttccattctg tcatattttt agcaaaagat acttttccaa
    33841 ttcccggatt attccataaa agtccataac ctagactaga aatataaaaa ggaactgata
    33901 tttgagaatt tctttgggct aactccaaaa cagtattctt taaatctaaa aatttatgtt
    33961 gatattgtcc cattccaaaa atcttttcag aaggctcaga ttcaaatcta gtagttactt
    34021 caaattctcc actatagctt ggtcgatatt ctcttgattt taactttaga gtagagttaa
    34081 agtctttggt aatctcaatt gtccctacat cttctccacc atcatcatgt tttacagctc
    34141 ttaatcgaat atattctttc aataatattt catttttatc attataaaaa gtaattctat
    34201 ctctatggtc taagacagct tttatctttc catttttaat gattgcactt ccatcttcat
    34261 ttttattaat tgtaatatca tctttattta acttaggttt ttcgttaaga gcatagtttt
    34321 catcaacaaa attttggtct acaaacgacc taatacgtaa agagtttttt ccccatgctt
    34381 ctattcgcaa tagttcattg tcaaatcttt tttcaatata gtcttcagat atttttatca
    34441 cggctacctc ctaaatcaat ggtataatat tctatctttg tgtagcttaa gttaaataat
    34501 gtcgtttagt atcgttattt ataaattagg ttttatatat aattcatttg tacattaaac
    34561 taacttacca ataatatact ttatttgact ttgtttgtca atcgctttcc ggattttagt
    34621 aaaattttct aatatattgc tggaaagtcg ttcttaatat cttttattta tacttttaat
    34681 atctgtgatg atacctatat acatctagtt tttttaaaac acatacagga ataaagtttg
    34741 cctattatgt agataatatc ggacttgaaa atatgtatag tgaccttata aatacagata
    34801 ataatatatt agatattgtt caaaacaatg gattttataa ttataaataa tttatgaaat
    34861 tatttaataa aatatataat tgtataccaa gtcaaaaacg acaacaaata aataaaacta
    34921 aaaaagatgt tgtctcaaaa tatagataaa tttatttttc attgctaaaa tgattaaaat
    34981 atatttgatt taatatactt gatttaatat aaaaaaagag tgtctcataa actaaaaagt
    35041 tcacttttag acactccttt atatatatta tctacttctt aattcattta ttacctctct
    35101 acattttctt tcaactagtg gatacatctt tataagtact aattactcca cttaaaaatg
    35161 gttcctgtac tgtccatcag tcatattttt ctgccaaata taatggtgtt tcataatgag
    35221 acaataaata tttatatctc tacttatctt ctctaagctc gtcaaatcca actataggta
    35281 tatttaaatt atattcttta agtagctttt ctagctcttc tataaaaata cctttcccat
    35341 ccaccatttg tatatcattt attttatcca tcaattcatt gcaaccactt aactcaccaa
    35401 accaacgttt agaactacat gtcttattat aaccacaact tggactgcca tctattgcaa
    35461 tgatactttt tatatcataa tcatttttta aatattcatc aaactgcctt acatgatgta
    35521 ttaacatttg cctacattgt tctctaaaaa acaaattgtc aaactgttct tttacatgtc
    35581 cccacctatt tattccatac ataatcattt ctgggcatgg tagttgaatt attccatacc
    35641 ctttatttat taaatctatc gctatatttt gtgctccctt aaattctgac aatccctcca
    35701 ctttagaatt acaatttaat atacaatgac atactactac aatctctcta tttcttttca
    35761 taataatctc cttagttatt cttaatttta atgatactac atattttgat aattatatta
    35821 tttatttgtt ctatatttcc aatattctat atagaaatat acaattagta atcttttata
    35881 atctatacta tgataaatgt atatattttt ttaggaggta ttataattgg atactaaaaa
    35941 agtcacattt tcttcaatgt gcatagttat taatattgtc ttaggtatgg ttatatctat
    36001 gataaatata ccattattat ttttagatac agttggtact gtacttgggg ctgtcgtatt
    36061 aggtcctttt tggggtgctc ttattggtgg atgtacaaac ttagttttag gtgttatatc
    36121 aggtcctaca aatatacctt ttgcccttgt aaatattgtt cttggtctta ttgttggata
    36181 tatttctaag aaaaaaggtt ttggttataa agaagctatt attacaggag taattttatc
    36241 tattgtttgt cctttaattg gtactcctat ttcagtttta ttgtttggtg gtttaagtgg
    36301 aagtggtgct gatttattgg ttggtttttt agttcagtct ggtcagaaga tatttactgc
    36361 tgcgttcttt ccaaggattc ttagtaatat agtagacaaa cctttgtctt gtattatggt
    36421 ggtatatttt ataagtaaaa tgcctaaagg ttttataaaa caatatagta aaaatacttc
    36481 tagttcatat taataaatca tttattatgt aaggtttatt actctttaaa atgctatata
    36541 ctcattttta tataacattt ttattaataa tttaattaga tagtatttgt attactttaa
    36601 ttaaacgtaa cctcttgata taaatttgag ctataaatct atatcaagag gtgctatttt
    36661 atttttaata taattaatat tctattacgc aaaaaatgca tatatttcat tattttatgg
    36721 aaaatattac ttcatttaac tctatatcaa actcattaag taaaaatcta attatattta
    36781 atttagcctc tgtatttaaa tttgtttcta aatatatatt ttctgatatt ttaatacctt
    36841 ttcttaattt atatgcatct ctagacttaa tattatctat aaaatctctt ttataagttt
    36901 tgtctacaat actgttaaac cttacagaat ccaaatcata taaagtaaga gcaacttgtt
    36961 cataaaattc tgtccaattt ttagccttat atgactctcc taatatacta aatgatacta
    37021 tactttcatt tgtaaaatta acatcatcat cctctaacgt aaatatattt tcactgttac
    37081 ttggaggttc atatgtaaca cttggatatt tccaaatttc tacagctcta tctagtaata
    37141 tcttagttct attttttatt tcttcttcat tccatttatc tatagatgaa atatatttat
    37201 ttagataaag cctactatct ttaaatccat cttccatttc tttcttttct tcaaatgttt
    37261 tattacttag ttttgaatta tatcctgtca aagttaaatt tccaattgta tgtaaatatt
    37321 tatcatgtat ctccttatag ttatctccta gtgattcctt ccatttattt gttaatgttt
    37381 gtggcattat atgctctata tttagcatat tattattgat taaattttct aaatcaacaa
    37441 tttctttatt attataattc tctaacctct caagtatata taacttattc tttgacttag
    37501 tattatatat atctttagtt tcaaaagcat ttgaaaattc actgtcagta ggaaatcttt
    37561 gagatgattt cttatttata aaaatatatc ttaatatatt agaatagttt tctttataat
    37621 cactaaattt tttaatttcc cttcctaagt tcataaatac tttattcagt gcattcggag
    37681 gtacatcaca tactattctt cttaatataa aacattctac taaattaagg gattctacaa
    37741 gtactttttt atttattata ccttcattat aatcatcaaa taattctaat ataaacggat
    37801 atgatacaaa tatttcaagt ttgtttatcc ttttcaaaac tttgtttaca tcattatcat
    37861 cagtacatg
//
LOCUS       DAEOTL010000035        37214 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEOTL010000035 DAEOTL010000000
VERSION     DAEOTL010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37214
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.035"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(112..306)
                     /locus_tag="KRH82_002059"
     CDS             complement(112..306)
                     /locus_tag="KRH82_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655338.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWVDRVRANSYSYENKIAK"
     gene            complement(615..2144)
                     /gene="lysS"
                     /locus_tag="KRH82_002060"
     CDS             complement(615..2144)
                     /gene="lysS"
                     /locus_tag="KRH82_002060"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBG8655339.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2159..2638)
                     /gene="greA"
                     /locus_tag="KRH82_002061"
     CDS             complement(2159..2638)
                     /gene="greA"
                     /locus_tag="KRH82_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBG8655340.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2747..3715)
                     /gene="dusB"
                     /locus_tag="KRH82_002062"
     CDS             complement(2747..3715)
                     /gene="dusB"
                     /locus_tag="KRH82_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBG8655341.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3852..4622)
                     /locus_tag="KRH82_002063"
     CDS             complement(3852..4622)
                     /locus_tag="KRH82_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBG8655342.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4641..5231)
                     /locus_tag="KRH82_002064"
     CDS             complement(4641..5231)
                     /locus_tag="KRH82_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBG8655343.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5414..6382)
                     /locus_tag="KRH82_002065"
     CDS             complement(5414..6382)
                     /locus_tag="KRH82_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBG8655344.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLVVSALIAVNALGDVYENGKVIAGALNDKRTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6375..7352)
                     /locus_tag="KRH82_002066"
     CDS             complement(6375..7352)
                     /locus_tag="KRH82_002066"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBG8655345.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPNMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7667..9637)
                     /gene="ftsH"
                     /locus_tag="KRH82_002067"
     CDS             complement(7667..9637)
                     /gene="ftsH"
                     /locus_tag="KRH82_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBG8655346.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9671..11059)
                     /gene="tilS"
                     /locus_tag="KRH82_002068"
     CDS             complement(9671..11059)
                     /gene="tilS"
                     /locus_tag="KRH82_002068"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBG8655347.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDNFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDCIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11242..11670)
                     /locus_tag="KRH82_002069"
     CDS             complement(11242..11670)
                     /locus_tag="KRH82_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBG8655348.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11687..12493)
                     /locus_tag="KRH82_002070"
     CDS             complement(11687..12493)
                     /locus_tag="KRH82_002070"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBG8655349.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12695..13180)
                     /locus_tag="KRH82_002071"
     CDS             complement(12695..13180)
                     /locus_tag="KRH82_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBG8655350.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13231..13890)
                     /gene="spoIIR"
                     /locus_tag="KRH82_002072"
     CDS             complement(13231..13890)
                     /gene="spoIIR"
                     /locus_tag="KRH82_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBG8655351.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14035..14715)
                     /locus_tag="KRH82_002073"
     CDS             complement(14035..14715)
                     /locus_tag="KRH82_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8655352.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14699..15589)
                     /locus_tag="KRH82_002074"
     CDS             complement(14699..15589)
                     /locus_tag="KRH82_002074"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBG8655353.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15707..17257)
                     /locus_tag="KRH82_002075"
     CDS             complement(15707..17257)
                     /locus_tag="KRH82_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBG8655354.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17351..17617)
                     /locus_tag="KRH82_002076"
     CDS             complement(17351..17617)
                     /locus_tag="KRH82_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBG8655355.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17765..18625)
                     /gene="yabG"
                     /locus_tag="KRH82_002077"
     CDS             complement(17765..18625)
                     /gene="yabG"
                     /locus_tag="KRH82_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBG8655356.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18709..19647)
                     /locus_tag="KRH82_002078"
     CDS             complement(18709..19647)
                     /locus_tag="KRH82_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBG8655357.1"
                     /translation="MKFLDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19757..19918)
                     /locus_tag="KRH82_002079"
     CDS             complement(19757..19918)
                     /locus_tag="KRH82_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655358.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19928..20425)
                     /locus_tag="KRH82_002080"
     CDS             complement(19928..20425)
                     /locus_tag="KRH82_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBG8655359.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20540..21250)
                     /locus_tag="KRH82_002081"
     CDS             complement(20540..21250)
                     /locus_tag="KRH82_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBG8655360.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21426..21956)
                     /locus_tag="KRH82_002082"
     CDS             complement(21426..21956)
                     /locus_tag="KRH82_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655361.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKPIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEIVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(21973..22203)
                     /locus_tag="KRH82_002083"
     CDS             complement(21973..22203)
                     /locus_tag="KRH82_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655362.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMSVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22218..23612)
                     /locus_tag="KRH82_002084"
     CDS             complement(22218..23612)
                     /locus_tag="KRH82_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBG8655363.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23738..24991)
                     /locus_tag="KRH82_002085"
     CDS             complement(23738..24991)
                     /locus_tag="KRH82_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655364.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25042..26196)
                     /locus_tag="KRH82_002086"
     CDS             complement(25042..26196)
                     /locus_tag="KRH82_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8655365.1"
                     /translation="MSNNINQNLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26756..27325)
                     /locus_tag="KRH82_002087"
     CDS             complement(26756..27325)
                     /locus_tag="KRH82_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBG8655366.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27528..27755
                     /locus_tag="KRH82_002088"
     CDS             27528..27755
                     /locus_tag="KRH82_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBG8655367.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(27974..28717)
                     /locus_tag="KRH82_002089"
     CDS             complement(27974..28717)
                     /locus_tag="KRH82_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBG8655368.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAAPQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28885..29757
                     /locus_tag="KRH82_002090"
     CDS             28885..29757
                     /locus_tag="KRH82_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8655369.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29757..30422
                     /locus_tag="KRH82_002091"
     CDS             29757..30422
                     /locus_tag="KRH82_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBG8655370.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30443..31300
                     /locus_tag="KRH82_002092"
     CDS             30443..31300
                     /locus_tag="KRH82_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8655371.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEKGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31456..34002)
                     /locus_tag="KRH82_002093"
     CDS             complement(31456..34002)
                     /locus_tag="KRH82_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8655372.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34002..34688)
                     /locus_tag="KRH82_002094"
     CDS             complement(34002..34688)
                     /locus_tag="KRH82_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655373.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34771..35760)
                     /locus_tag="KRH82_002095"
     CDS             complement(34771..35760)
                     /locus_tag="KRH82_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655374.1"
                     /translation="MFRNREFRKLAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35747..36433)
                     /locus_tag="KRH82_002096"
     CDS             complement(35747..36433)
                     /locus_tag="KRH82_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655375.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(36933..>37214)
                     /locus_tag="KRH82_002097"
     CDS             complement(36933..>37214)
                     /locus_tag="KRH82_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655376.1"
                     /translation="KSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGND
                     STRDGFKMRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
BASE COUNT        11908 a         6884 c         4168 g        14254 t
ORIGIN      
        1 gttttttatt ttaaaaaagg ttataacttt tggttttttt taataaatat aattaaaact
       61 aatagatata acccttgata ttacaaacaa tgcatgcata tataatttta cctattttgc
      121 aattttattt tcataagaat atgaattagc tctcactcta tctacccaaa catttatact
      181 cttaacttta ttaacattag ttgtaccctc aaaaatatcc attgcatcct tacaaaaata
      241 tatcataaca tcaagaacca aaaatccaac acaaaataaa cataaaaaat taattacttg
      301 aaacatcaga cattccccca ataatttttt atatatagta ttctcataaa ttattctttt
      361 taccttctca taaattattc taaatatttt cataataaat tactttcaat catattttct
      421 aaatataaag tctcaatcaa caaaaactaa tatcaatttc taacgtttgt tggtaattta
      481 taaattaaat atctaaaaga atctttgaag catataaaaa gcattctaca ctgacatttt
      541 aaataaaatt tagctattta ttgataattt aatagctaaa ctttatttaa aacttagtag
      601 aatgctaata tttcttagtt ttcttcttct ttatttggat tgttatcaat aggtttcata
      661 gtcgggaata ataatacatc tcttatagat ggagagttag ttaataacat aattactcta
      721 tctataccta ttcctagtcc tcctgtagga ggtagaccta cctctaatgc ttttaagaaa
      781 tcttcatcca tttcaaaagc ttcatcatca cctaattctc tttttcttaa ttggtctata
      841 aatcttcctt tttggtcaat agggtcatta agttcagaaa atgcattagc taactcccac
      901 ttattagcaa atgcctcaaa tctatcagtt cttcttgggt cttcaacatt tctcttagat
      961 aatggagata cttcaactgg atgatgagtt ataaatgttg gttggattaa tttatcttct
     1021 ccaaattctt caaagaaagc atttattact tcccctcttc tcattccagg ttttatctct
     1081 ataccttttt ccctagcaac ttctagtgcc tcttcatctg tatttatagt agaaaaatct
     1141 acaccagaat attctttaac acaatcttcc atactcattc ttttccaagg tggtgtaaag
     1201 tttatttctg ttccttgata gttaactatc atacttcctg tagcaacttc agccatatgt
     1261 gcaataacat tttctgttat ttccatcata tcagtatagt ctgcatatgc ttgatataat
     1321 tctattgcag tatattcagg attatgtttt aaatccatac cttcatttct aaacattctt
     1381 cccatttcat aaactttatc aaatccacca acaataagtc tttttaaata caattcattc
     1441 gctattctta aatacattgg tatatgtaaa gtattatgat tagttataaa tggtctagca
     1501 tttgccccac ctgctatagt atttaatatt ggagtctcaa cttctaaaaa tcctctatca
     1561 tctaagtatg ctcttaatgc ttttaatgct tttgttctaa ttaaaaaagc attttttact
     1621 tctggattta ctattaagtc aacatatctt tgtctatatc ttagttcttg gtcttttaat
     1681 ccatgatatt tttctggtaa aacttgtaaa gatttacata gtaatactac agatttagcc
     1741 tttacagata tttcaccttt tttagtttta aagatttctc cttcaattcc aactatatct
     1801 ccaatatcat atgttgaaaa tacactatat tcttcctctc ctatagcatc tagtcttaca
     1861 taagattgga ttcttccctc ttggtcttga atatctataa agccagcttt tccttgtatt
     1921 ctcttgctca ttatacgtcc tgctattttt gtagttttac cttcaagaga atcaaagtta
     1981 tcttttatat ccatagaata atgagttcta tcatatctac tttctttaaa aggatctcta
     2041 cctgactctt gtaatttttt tagtttatct cttcttactt gaagtacttc actaaggtct
     2101 tcttgaattt gcgcttcttc attgctttgt tgattatttt tcattttttt cctccaaatt
     2161 atcttcttat ttctaatatt tcaaacttag caactccatc aggaacttgc acttccacaa
     2221 cttctttcgc agctctacct aaaagtgctt tccctacagg agattcgttt gatattttac
     2281 catcatatgg gtctgcttct gtcgaaccaa ctatagtata ttcaacctct tcatcaaatt
     2341 ctaaatcctt aactttaact attgatccta ttgtaacaac attaaggtct attttgcttt
     2401 catctatgat aacagctttt ctaaccatat tttctaattt taaaattctt tcttcaactt
     2461 gtgcttgttc ctttttagct tcatcatact cagcattttc agataaatca ccaaaagata
     2521 tagcaacttt tattctctct gcaacttctt ttctctttac aacctttaag ttttctaatt
     2581 cttcttctaa tttatcatat ccctcttgtg tcaataaaaa ctctttattt tcttccatta
     2641 taaatacaac tccttcacaa atttcttagg aattttccta attatatttt aaaaatttta
     2701 taatcttttt ttaatttatg cgctatatta taagtcacta ttatttttat gtcaaggagt
     2761 cttccatata gtactccaat ttcgacacaa cttcttgata gtcttctatt ttgttaattt
     2821 catcccttaa ttttgcagag tttctaagtc cttttaaata ccaagcgatg tgttttctca
     2881 tttcccttac agctacatac tctccatgtt cttctactgc aagttttaaa tgcttaatgg
     2941 cagtacttat tttttcgtta agagttggct ctggcaaaat ctcgcctgta ttcatataat
     3001 ggtttattct tttaaatatc caagggttac cttgagcacc cctacctatc attatagcat
     3061 cacaaccagt tttgtctaac atatttattg aatcttctat tgtaaataca tcaccatttc
     3121 ctataacagg tatactcaaa tttttcttaa tctctgcaat tatatcccag tctgctttgc
     3181 ctgtataaaa ctgttctcta gttcttccat gtattgctaa agcacttatt ccacaatcct
     3241 ctgctatctt tgctatttca acagcattta cactattatc atcccagcct tttcgaatct
     3301 ttaaagtcac tggctttttt gagttcttca ctactgccct caatacctct tctgcaagct
     3361 taggattttt cataagtgct gagccatctc catttttaac tacttttgga gctggacacc
     3421 ccatatttat atcgagaatc tcatttgaat aatcattcat tatctctgct gctcttccca
     3481 taaactctgg ttctgaaccg aatatctgaa ctgctacagg atgttcttcc tcttctatct
     3541 taagcatttt tttagtattt tcatcatcat agcaaagtgc cttaccattt atcatttctg
     3601 tatataaaag cccacatccc tgttctttac aaattaatct aaatggaagg tctgttacac
     3661 ctgccatagg tgatagaaaa actttatttt tcaattctaa atttcctatt ttcattgttt
     3721 ttctcctatt tttgccttta ttttgtgatt taactttaaa ttcttatttc ctcattataa
     3781 tataccacat atagctagaa atctatcata aaaagggaat tggatatata acccaattcc
     3841 ctgtatatta attattcttg gtttttttca tatattattc tcaatccttc tagtgttaaa
     3901 aaaccatcta cataatctat acttttcgtc tctgaagcaa tcagtttagc taatccacct
     3961 gtagctataa ccttaacatc atcacaattc aattctttct tcatcatact tattattttg
     4021 tcaactaaac caacatatcc ataaattatt ccagattgca tggctgatac agtactctta
     4081 caaatagtca tacctggctt agctaattct actctaggta atttagacgc actttgaaat
     4141 aacgcctcac tagatatttt tattcctggt gctattgttc cacccaaata ttcacctttt
     4201 tcagagatag cacaaaatgt agttgctgtt ccaaaatcaa caagtatact tggtgctcca
     4261 tacttttcta tccctgctac agcattaact attctatctg ccccaacttg ttttggatta
     4321 tcatatttta tatttagacc tgtttttatg cctggaccta ctattaatgg ctgtttttta
     4381 cagtacttta tacaaaagtt ttcaagagaa tgcataacat tcggaactac agatgatatt
     4441 ataacatcat caatatcact tatattcaca ttatcataat caaataggtt acttatcagg
     4501 attccatatt catcagacgt tttttcccta tctgttttaa ttctccagta attaactaat
     4561 ttgtcacctt tatatatacc taaaaccata ttagtatttc caacatcaaa tactagaagc
     4621 atatgtcatt aaccttcttt ctattttttg cttttcttaa gtacagtggc aacagcagct
     4681 actactaaag cccctactat tgcttctggc accccatttg ctgcggcaag agccattatt
     4741 acttttcctg ctgaaccact tttacccatt gcatgaagat acttgtcagc atataagaca
     4801 tatatcattc ctaaaactcc agctgtattt aacagagaac ctattgcccc tgtaattaaa
     4861 cctgatatgt ataccttatt tgtagcctta attattaact gatatacata ataagctaat
     4921 acacctatca taactcttgg taatattgaa actaatggat ttataaaaac aaaagatgtt
     4981 actgttgggt ttgttatagc atttaagaga cttgatatcc caaatataaa tcctattgct
     5041 gccccaacta ttggtccttc cataatagct ccaataataa ctggtatgtg cattatagtt
     5101 gcttttgtag gtccaactgg aataaatccc aatggagtca tagatagcat aatagaaata
     5161 gctgatagta ctcctattat agtcatcttt cttacattta cttttcttac tgatgcactt
     5221 gtgttcatca taaaaaatac acctccgttc cagctcatta agatgccgga ctacttaatt
     5281 ttttaatttt ttcgtttttt tcttataatt atgagtcaag ctaccattgt aggatgcccg
     5341 ctctaacaag aataatttta tcaagatgag ttgccattgt caacaatttg acaagaaaaa
     5401 tatgctaatt tcatcatatt tctcgttttt ttactatatc tttatatgcc attatatttt
     5461 ctacactatc cgcttttttt actgcattta ttatactttt ttccacaacc tctacagcca
     5521 atgaacctac taatgttata tctgcttcta tttctcctgt tgatattgtg aatattgtat
     5581 ctccatcatg aggtgtatgg ataggaaaaa tagacttagc atatccatca tgtcccattt
     5641 gagatatctt tttacatcca gctttggtta acttagcatt tgttgcaatt atcccaattg
     5701 tagtattatc tacactaaat ccacctttac tttcaccttg tttcattaat ttatatgtat
     5761 caattgtttc tgtcctttta tcatttaaag caccagctat aaccttacca ttttcataaa
     5821 catctccaag agcatttaca gcaattaatg cagatacaac tagaccatta tctaatttta
     5881 tagaatagct acctattccg cctttcatag catattcctg acctcttatc tttccaacag
     5941 tggctccaca acctgctcca taatttcctt gatttaaaat atcagtattt gcaacttcac
     6001 aagctctata acccatcttt aaatctggtc tacatttaaa gctccctact cctaaatcaa
     6061 ataaaactgc tcctacaact ataggcactt tacctacacc tacatcaaag ccaattcctt
     6121 tttcttctaa gtatctactt acaccacaag tggattcaag accatatgca gaacctccag
     6181 ccaaaactac tgcatgaact ttttgaacca tatttacagg gtctaataaa tcggtttctc
     6241 tagtccctgg agcagagccc cttacatcaa caccgcaagt agctccttct tcacatatta
     6301 ctactgtgca cccagtaaga ccatttctat cctcaacctg cccaaccttt aagccttcta
     6361 tatccaaaat attattatac atatcctttt tctcctctta tagaaacttc acctgaaata
     6421 atttctttta tacttccatc acttctttga actaataaat ttccctcttc atttatgtct
     6481 aaacatttca ctagttctct attatctcct tttaatacat atatattttt atctataatt
     6541 gcagaataat ctctacatat ttttaaggtt ttttctttgg aattatttac agtataatct
     6601 aaatataatt tttcaaattc agtcaataca ttcctaacaa tatctactct ggataacata
     6661 tacccttctt tatacaatga tgtggctttg tcagctattt cttgttcaaa atccattatt
     6721 ttaacattta ttccaattcc aagaacaaca taatttgttc tttcaatttc agcagataac
     6781 tctgttaata taccacatat tttttttcca tttaaaataa catcatttgg ccattttatt
     6841 aatgtatttg ctcctagatt gtttaaagct ttcgttacac ttgctcctgc tattaaagtt
     6901 ataaatggag ctttgaatgg ttccatattt ggttttaata taatactcat ccagattcct
     6961 tcatgaggtt ttgaatccca tcttcttccc aatcgtcctt tccccatgtc ttgatgttca
     7021 cttaaaatca cagtcccatc tacactattt atagctatcc ttttagcatg ttcatttgtt
     7081 gaatctatag tgtcaagatg ttcaatattt tttccaataa actctgtatc taatttatag
     7141 taaatattct gtgggcttaa taaatcagtt ggattttccg ctaatcgata ccctttttta
     7201 tttacagatt ctatattata tccctcttct tttaaggctt tcatatgttt ccatatagct
     7261 gcacgtgaca cccctaattg ttttgataat tcttctcctg aaataaattc agatttatta
     7321 tttaatataa tctctattat tttatctcgc atatttcacc tctaatatga cataatttca
     7381 tgacttattt tcttctaata aataattata cattattaat atacttttaa tactattaat
     7441 tttaaatttc ctttttaatt attataatgg ttgttttata ttttatattg atgatttata
     7501 taattttaca ttttatttaa ataattttaa aataataaaa aaactgaaag tatcaattaa
     7561 attaatacat gcaaatataa tttgcttatt aatttaatat tatactttca gttttagtat
     7621 ttaatccaca tcagataata atcttaaaat gaccaaggtc ttaaaactat ttatctttat
     7681 cagatttatc ttctaaattt ttatttatat caataacatt gtttctttct tcttcatctt
     7741 tttctaattt tatagttaat tgttcttcaa cttctttaga agaattttcc tctgtaactg
     7801 cattttcaat ttcattcaga ggtaactctt tattaaatgc ttttacaaat tgttctgcat
     7861 ctaaagtttc atatataagt aaagcttgtg ctacatactc taatctatcc atattttctt
     7921 gtaatatact tcttgtctta tcatatgcac catcaactat acgctttgtt tcttggtcta
     7981 tctcaaaagc aacttcttca gaataatttc tcttacttga aaaactatta cctaggaata
     8041 cttcatcatc actgtcaaat gacattggac caagcttaga actcattcca tactttgtta
     8101 ccatacttct tgcagtagct gtaactcttt ctaagtcatt tgaagcacct gtagatacat
     8161 ccttaagtac tagctcttct gctactctac caccaagtaa aactacaata ttttctttca
     8221 tttcattttt tgtagcatag aacttatctt caacaggaag ttgcattgta aaccctccag
     8281 ctcttcctct tggaactatt gtaacttgat gaacaggact tacttcttca agtacatggg
     8341 cacaaactgc atgccctcct tcatggtatg ctgtaagtct tctttctttc tcacttatta
     8401 ctttcgattt tttagccaca cctgctataa cctttgttat agcttcttct atagtttcca
     8461 tcttaatttt cttttctctt tttctagctg ttaatattgc agcctcattc attaagttct
     8521 ctatatcagc aggagtaaat cctggtgttc ttctagccaa gacatccatt tttacatcat
     8581 cacttaatgg tttatttctt gagtgaactt taaatatagc ctctctacct tttacatctg
     8641 gtgtaccaac aacaacttgt ctgtcaaatc ttcctggtct aagtaaagct gggtcaagta
     8701 tatctggtct atttgtagct gccatgatta ttataccttg atttacccca aatccatcca
     8761 tttcaactag aagttgatta agagtttgct ctctttcatc atgacctcca ccaagacctg
     8821 cacctctttt tctaccaact gcatcaattt catctatgaa tatgatagct ggagcacttt
     8881 tcttagcctg ttcaaataaa tctcttactc ttgaagcacc aaccccaaca aacatctcaa
     8941 cgaaatcaga accacttata ctgaaaaagg gaactcctgc ttctcctgca actgctcttg
     9001 atagatatgt tttaccagtt ccaggaggtc ctaccataag cattcctttt ggtattcttg
     9061 cacccaattc aatatatttc ttaggattct ttaagaaatc tactacctcc tgcaaatctt
     9121 ctttttcctc atctagtcca gctacatctt taaatgtaac tctagttttt tcatcatctt
     9181 tatgaacctt agcttttgat ttgccaaaac tcataacctt tccgcctcca ccttgagact
     9241 gattcataaa cacgaaccaa ataatcacca tgaagaatat taacagtaat gtaggcaaca
     9301 tttcgacaaa ccaaggtgta gatggcttag cttcaccacc aaaagttagt ttcccagcct
     9361 tagcttggtc taacacctca tctgcaagtt tatttcccat cacttctgtt ggaacatatg
     9421 acttaaactt tgtatttgta tcttttatag taccttctac agaagtttga tttacaaagt
     9481 ataatcttga tatattctca tctgttaatt ctctatatac ttcagagaat tttaaatctt
     9541 ttattttttc tgtaggctta cctgagaatt gaactatacc tactataatt ataaaaacaa
     9601 gtagataaaa acctgcccct tttagcaact tattcaatat agaagccctc ctttcataca
     9661 ttgctttgcc ctataatttg ttaaaattaa tttttaatac ttcttttgtg ttttcatcaa
     9721 ttttataatt ttcactgatt ttataatctc caacacatat tattccttca ctatctgtga
     9781 ttataggaat tttacatctt tcttctcttg ggatttttaa atctatgaat aaatctttca
     9841 cttttttact tcccatagca agctttatct tatcaccttg ccttctgctt cttattacta
     9901 tacccccttt taccttatta aaatcaaacc ctttagatga attgtctaat ttcatactct
     9961 tatacctatc tatgctcatt acttgggtct caataatttg ttttaattct tttattttaa
    10021 taaacccatt actaggtaca ttgtaataaa attcaatttc ctcattaaca atttcctcat
    10081 tcgttaatat tatacagtct ttttttctat aaacaaatat atttcttgga agagttaaca
    10141 ttttatttac ttttgaatta tcttctaaag acattatatc ctctatatgt ctttggtcaa
    10201 caaaattagt atctcctagt atatgtttta tggaatttct aagaactcta actttgatag
    10261 catcatgtaa gcaaacaaaa ttgtctaaat ttatctctac aaagcctttt tcttttatat
    10321 tcgaaacttc tctaaattta gcttctgcct ctttctcaat ataatcgtta tcacttttta
    10381 aactattgct catcctcact atagattcta ttacatttga attaaaatta tccttcatat
    10441 atggtaaaag gtctaacctt atcttatttc tagtgtatat attttctaaa tttgttttat
    10501 ctatcctcgg atttaaatta taagcttcac aatactcctc tatctcattt ctttccacgt
    10561 ctaatatggg tctaattatg caattatctc taatataatc aattcccttt aaacctttta
    10621 aacctgttcc tctcatgata cgcatcataa ccgtttcggc ttggtcattg agattatgac
    10681 ctattgctat tttattggct ttaatcttat ccttaatttc ataaaacatt tcatatctta
    10741 gcttccttgc tccttcttct aatgataatc cctcattttc acaatatttt ggtacattaa
    10801 tagactttac aaagaatata attcccatat cctcacaaag tttagataca tataatgcat
    10861 ctttttgagc ttctatccct cttatttgat ggtttaaatg tgctgcatat atttctatat
    10921 taaaatcttt ttttaatcta tttagtacat gcaataaaca aactgaatca ggtcctccag
    10981 aaagacctaa aactatttta tcgccttttt gtattaaatt atgtttattt atagtactta
    11041 gtaccttatc aaatatcata tttatccctc ttacacttag ttttattcac ttttaagtat
    11101 actttctata aaaaaacgct aaacccttgt atcaatttta agaaattaaa gtttaatata
    11161 aatataataa taccaaataa attaaataaa aggtagtttt ttcactacct ttataaaatt
    11221 tctggaaaat agccatagtt attatttagt acctatgtat atatctattt tattcctacc
    11281 taaaaataaa tcttgtacct ttatattata gtctattttc aattttatgt gttccccttc
    11341 ttgtatattt atatctaatt ctcttgtatc aatatcaatt aataaagtac cttgtggggt
    11401 cacatacttt gtagtactac tttctccaca tttaaacagc attgttgagt taatagcacc
    11461 aaactttttg atactaactt gatttttaag tatctttata gtattagtta tttctatatt
    11521 ttcttctttt tccttgtaaa taacatatat tccatcattt ttataaaaaa ttttaccaaa
    11581 ggcagtcatc tctatggtgt ccatatttcc tttttcatca tattgtctag tatttatact
    11641 tatttttaca ctcaacgatt tttcctccat agattcttca tataaactag tatttttgta
    11701 tttctacttt ttgaatctta tcaatttttt tctttaagaa ctctcttgct atatctgaaa
    11761 atttttcagg tatatctgat acataatatt gataagttcc atgaatttct gtattgttta
    11821 taatattttg cacctctaaa atctttttta aatcctttgc agtctcttta gctggattaa
    11881 caagttttat atgctctcca acttcttcac ctattgttct ctttaaaata ggataatgag
    11941 tacatcctaa cactaaagaa tctatatttt tttctttcaa ttcttgtaaa tatatctttg
    12001 ctgtcaattt agccacttct gtatttgccc atccttcttc aacaataggt acaaataaag
    12061 gacatgcttt attaacaatt tctatactct catctatttt agatatttcc aagttgtatg
    12121 cttttgaact tatagttcct tcagttccta ttattcctac aattttgttt tttgtagaac
    12181 ttacagctgt tctagctcct gcttctataa ctccaattat cggtatatca tatttttctt
    12241 gagcttcttt taagcttctt gcagtagcag tgttacatgc tataactata gcttttacac
    12301 cttttgtttt taaaaagttt atagcttgaa aagtatattt aattatagtt tctttggatc
    12361 ttgaaccata tggtattctg gcagtatctc caaagtatat tatatcctca tttggtaata
    12421 tcttcattat ctcttttaga actgttaatc cacctaatcc cgaatcaaaa actcctattg
    12481 gtttattgtt catctttata caacacctac tttacatttt tgtgtttaac aacaacttat
    12541 ttatcgctaa aatttatatt tatattcata attaatatat tattacctaa atgattatta
    12601 tagtttattt tacacaaaaa ataaaggagc tatcttaaat tagaaaataa tttctacaaa
    12661 aagacaactc ctttcactac ttaaaaattt aaatttattt tgcaaacaca tgatttccta
    12721 ttctcatata aggattcaat ctatttatcc atttgcaagt ggctatttct ggattccaaa
    12781 aatatactgc tttattagtt gggtcagttc cataaagagc ttcctgagct gctttacgtg
    12841 ctgagtctgt tggtgccatc tttattgaac catcaagcac aactgagaaa gcattttttt
    12901 gatatatgac ttcttctatt gtgtctggaa atctagggtc caatactcta tttattacta
    12961 cagctgctac agcaacctgt ccctcatagc tttctcctct agcttctcct gcaaccaact
    13021 tagataataa catcaaatca ttatcagata aatttattac ttctttcttt gctatatttt
    13081 tttcttgttt gtttactttc ttaatatttt ctgttggttc atatgcaaat acctctttaa
    13141 taggcataaa tataaaagtc aaagctaata gtgtagccat cagtttactc cacctgtcca
    13201 tgattaaaac cactccttac attcttattt ttaaaatttt ttctctaaat ccttgactac
    13261 ttcaagtact ttaaacttaa tttttactct acttgttttt tttggtgtat cttgttttat
    13321 taacttatat tctttatcag ttaaaacttc cttcaactta tcatctgtag atttatctat
    13381 cactccatta gattcatcaa caaaacatag tggagggaac ataacacacc accagttttt
    13441 tccttcacct ttcccaatga taatctttaa tgctttatat tcaccagctg gaagaactat
    13501 attagaatat tgtttagtag ggaaattgct atattgtata cctaccttta cactgtaatt
    13561 atatccattt ttaagaataa tatttttact tatttcttcc agactactat attccttttt
    13621 tataatagct tcactttctt ttatactttt tgaattttga agctttggct gtaaatattt
    13681 tattacttca tctctaactt ttagtttaag ttcttggtct tcatctgtat tgctgtttgc
    13741 tataacatga aatcttatta atttatcttt ataatctttt gatatattgt ctactttttt
    13801 tacctcacca tttattacta ttgtcattat tgatatgact gatataagac ttaatattaa
    13861 tagtcccaat ctaatcttaa tttttctcat tgaaaattcc ccctcaagat aaatttatat
    13921 catcaattat gtccaattaa atttaattta ttcataatat tttttaatac taataaaaaa
    13981 agctatctta aaatgattac aatcatttta aaatagcttt ttaaacctta tattttataa
    14041 gtctttacta atcatagcct tatctatcat aaactgctct gctttttcta tatgctctgt
    14101 agcatacttc ttggatagct cactatcacc tttaattata gcatcaagta aatatttatg
    14161 ctcttcaaca atattatgtg atgtatcata agcagacata taggtaactc taaatctata
    14221 tacttgttcc cacaatgagt ttattaattg gattaatttt ttattattag ttgctttaaa
    14281 tatacattca tgaaattcta catcaagttt taataacgca tctacatcgg attccaaagt
    14341 gcttttttta aattcttctg atatatcttt aagcttttta atatcttcat cactaattct
    14401 ttcagcggca agatatgctg ctaagccttc taggcttgct cttacttcta atacatccat
    14461 aatatccttt aatgacatat ttgccacata cgcacctttt ctaggcaaca taacgactaa
    14521 accttctaat tcaagctttc ttattgcctc tctcactgga gtcctactta ctcctaattg
    14581 ttctgctagt tgcacttcca ttagcctttg accaggcttt aattttcctt ctaagattgc
    14641 ttctcttaaa ttctcaaaga ctacatctct taatggcttg taattatcca agttcagttt
    14701 agttaaattc tccacaaatt tcaacccctt tttgactgct attaacaaca tacacctgtt
    14761 tatatttttt taataattct ttttttccaa ttagagcatc ttctttattt ttaaatagtc
    14821 caaaaactgt aggaccactt ccactcatca tagaacctaa agcattattt ttcatcatta
    14881 cttgttttat atcacttatt tctttgtgtt tacctatagt aacattttca agaatattta
    14941 ccatgctttc tgatacagct tttatatctt cagattttaa acactctatc aaatatttat
    15001 tatttggtct ttttttaata ttattcaaat ctaatccttg ataaacttct ttagtagaaa
    15061 cgaataagtc tggtttgcat atcaatatat ttgtatcaca tggtaaacct ttgatgtttg
    15121 ttagcttttc tccaatacct tgagctaaag caggtcttcc tgatatacaa aaaggaacat
    15181 ctgcgcccaa attaagtcct atttctttta attcatcttc agataatcta agttcccata
    15241 ggtgatttaa acctactaat actgcggctg cattagaact tcctccagcc atccctgctg
    15301 ctacaggaat atttttttct atgaatattt ctacaccttt ttttatataa aatttatttt
    15361 taagtatttt ggcagcttta taaacaatat tatcttcatc taaaggaata tctaaactag
    15421 tgctttttac ctttatttca tcttcgtcta attcttttat ctttactata tcgtataaat
    15481 ctatcgtttg cattatcatt tcaacaaaat gataaccgtc ttgccttttt cccaagacat
    15541 caatggataa atttattttt gctctactct ttagtcttat aaaatccatt ctatcctcct
    15601 tgtttaaaga ataatgcatc actaacaata atattatact acaaaaaata aaataatagg
    15661 gtattataat accctattat acttaattac tttaaatttt ttaatattaa tctactaata
    15721 cgactttttt ttctaaaata agacacttac caggcttaat tggttcatca agttttatat
    15781 cattaagttc tgcaatttca ttttctgttg tattgtattt ttttgctata ttccagaaag
    15841 tatctccttc tttgcatata tatacgatta tgctaggagc tttagataaa tcatatacac
    15901 cttggtcttc tcccttgata ataaaatttt ctgctttctt atctaatgct tcagtaaatc
    15961 tcttaatttt gataatcagg tctatctggt ccctattcaa atcaacttcg actttatcaa
    16021 tacatgctgt attaaacaca gatgctgtat cagttagatt atccatttct atatcatgtt
    16081 caaatggaat ttcctcacta attttataaa ccaattttaa accttcaact gggacaaata
    16141 aaatttcaac ttttatgatt ccttgtataa tgcttttatt tccttcaata taactatttt
    16201 ctatagacat ggttggacaa acgcttacaa tatcttttat ttgtatatca tcattatcat
    16261 ttcttatgcc ttctctaacc ataaatgttt cttcactacg tcttaaagtc ttatttaatt
    16321 gaataggttt gtggtcaaat tttattatct tttgaggcga atatgcatct tgtaatactt
    16381 ctcttgtaac ttcatctgta acttttacct tacaacaagc catacaatct atttctaaaa
    16441 gacctgtgtt gctttcacta ttttgcttga aaatatgatt aaaatctgac atagacaaca
    16501 atacttcttc agtcatacca tcactaactc cagggacttc tacaaattga gtaaactcaa
    16561 tacctactct atccaactct acaagttcac cctcatatgt acaagctaac ggatttattt
    16621 ctaatactcc accaataata actttattgt cagtcactct actttctttt actttaacac
    16681 atggatttaa acttattata gattgaattt cctctgtgtt tattgttata gtatctctta
    16741 tagaactttc tgctttttct attccaacta tatcttgaaa acaaatttcc tttctgtgct
    16801 tttgtatgcc ttccacttgc gccacatctt ttacaatgtc taacctttgc ttttcaaaca
    16861 aacttcccct tatattcata agagctccta ctttaatctt tctctcattc attatagtac
    16921 aatccatatg ctctacttct gaaaataaca tgtattccat atcttgaata acattgtctt
    16981 tttctattac ttcgtttata tctacttttc cgtctacatt agaaatagta tttttatcat
    17041 ctgcaatata gattacatta taattaaaac tacctctgca aagtatcttc ccatctgcca
    17101 tttcaatttt tttaagtgat atgtatcctt ctgtttttac aatttcatat acatctaatt
    17161 ttttgtctgg tacaactgcc tccgcttcaa tgaatgtttg aaattttcca aagtctattc
    17221 tattgtcaac tttaattaca tctttaatta attccatagt ctacctcctt aagtattata
    17281 aaaatatcac actatattta tatttaagga gcaaaaaaaa aattacacct atttttaaat
    17341 aggtataatt ttaacttatt tgtaatttat cttgatctct aaaaacttgc aactttacat
    17401 tagatgttaa taaatctgag taactataag atactctagg atatccatta ctttcatcat
    17461 ctaactttat aacaaacacg cttggataaa ctttttctag tataccctct tttgtaataa
    17521 tctgctttct tcctttatta gctttcaaca atattttctt tcctatatgt ctctctaagc
    17581 ttactcttat cttatctaga gtttgaacag tagccacaat atcaccttct ttaacgttta
    17641 tatgtttaca taatatcaca tataaacatt tttgtcaaat gtttaaacta attattttat
    17701 atattttttg caaaaatgtc aatactattt ttgaagatat acagtataat tatgttaatt
    17761 tttgctaatg taatattgtt tttggcattg cccatctaaa ttttcctctt gtttcagaac
    17821 caccaattcc cttaacacct gtaatagtct gctctataac ctcatcaata ggaactacta
    17881 catcaattct tgaacaagca attttctcca ctataaaaac agggtctaat gcatgtatca
    17941 ttattcttcc aggcgaactt gcatagtttg ctcctgcact tattattttt tcataatttg
    18001 attggcatgc tcctgcgaat attacaagat tatccaaatt tggttgccat ttacgtgctt
    18061 cttttactgt tttaacaaaa tttgaagagt ttctatagtt actcatatct tctatatctc
    18121 ctctttttat tgtcattgca tcatgacctg ttattactag tatatccgga ttatattttt
    18181 ctagtagtgc tcttacttct ttatactgat tttgctctga aacagctaca cctactgcag
    18241 gtattccaag ttgagcatat acatccaagc aaatttttaa atattcttta tctccatcta
    18301 tctgtagtac ttttccaggc attccatatg tgttaggatt taattgaagt tttggaactg
    18361 ctctagtcat tcttttttgt ctttctttag cttttcttac tgacttatat aataaatttt
    18421 ctacattttt atctattaat atatctttta tatcaggtgc ttttactaat tctaggtcat
    18481 caatataagc atctgctatt actctaaatg caattccctt tagtatagct attttctcat
    18541 tattttcatc tacaccaaaa gagactattt taaatactat atctttgtta tgtgactttc
    18601 tagctacaat gtctcctacc ttcatagtta aacctccaat aaatttttat cttagtttat
    18661 actatgttcg atataaaact ttgtttccta atgtcaaaaa aacatttctt ataatacttc
    18721 ttttatcact cttaaagcat ttttatagta tatcttttct atatcatctt cactaaaccc
    18781 ttcttttttt agaggttcat acagtttacc catctgagat atatcttcaa tctcaacttt
    18841 tgaatctatt ccatcaaaat ctgaccctag agatacaaca tctattcctc caacatttac
    18901 aatatgtttt atgtgtctaa ccatatcttc aagtttactt tcacttttat cacttaaaaa
    18961 taagtggaag aagtttatac ctgtaactcc acctttattt gctaatactt taatcatatc
    19021 atcagttaaa tttctagaat gattcatcat tgctcttgaa ttagaatgtg tagcaattat
    19081 tggtttagaa gaaatctttg caatttcata aaatccacca tctgaaatat gagaaacatc
    19141 aaccaacatt cccaattcat tcatcttatg taccacttct cttccaaaat cagtaagccc
    19201 tttttctcta tattctactt tattatgagg aaagctcaat tcattcacat gattccaact
    19261 tattgtcatc attctaaccc ctaagtcgta aaatttcttt aaattttcta atttaccttc
    19321 aagtactgca ccttcctcaa tagataaaag agctgtaagt ttaccttctg attggttttt
    19381 cataatttct tcatagttag tagctaaagc tatttcatca ctattttttt tcatttcctc
    19441 atgaaattta tttgccatac tcatgcaata atcaaaagga tgttttactt cttcagtatc
    19501 aacaaaaaga gcaaatgttt gagctaatga atcccccttt ttcaatctgt ctatatcaac
    19561 agaatattta ttagacttaa gttcacttgt ttctacattt tccattaatt ttgctatagt
    19621 atcacaatgt aaatcaagaa atttcatatt tataccccct gtatatttta tatttatatc
    19681 taaaaataga aatagttgtc cttatagaca actattgaca actatttttt aatattcttt
    19741 ttaatattac ttaatcttat tcttctttta agttaggtat tactttttta acttcttcaa
    19801 tttgatgcca tgttttatct atattatttt cactaatata tttttttaaa tcagttaaag
    19861 atgtaaaatc tttaactgat aaattgtcat catcatctgc aaatcttaaa ataaacatga
    19921 gactccctta ctttccacaa catttcttat atttttttcc gcttccacat gggcatgaat
    19981 catttcttcc tatttttgct tctttaacta ttgttttaga cttcttataa gcctttatta
    20041 tttcttttct ttggtctgct ggtagtatat cttcccaacc ttgtaaatta tatagccaat
    20101 gagcctcaac agttaccata ttgttatata atttttccca atctattttt atagaaactt
    20161 ctttatcagc ttctacttct tctaaaacta tatcttcttt taagctttca cttattccat
    20221 ctatgaatcc catgaaaaat tcattagtag ttccaaattt ttcagccaat tcacttactt
    20281 taccttcaac aacatccatt ttattattta atatttcatt gtatattcca gcttcaactt
    20341 tcaaatattc ttcccagaat tttacttctg cttcttgact ttcatgatta tcacttaaat
    20401 ttctccattc agtatataaa ctcatacttt ttcctcctaa gtatacctat atttttatag
    20461 tttttatagt ataaaatctt ttagttagat tggaagtttc ttctttttga ttataccata
    20521 ttctatttaa agttaactct tatattatat cataattaaa caattctttt aatactttta
    20581 tagcatactc ttggtttata aaataagggc ttgtcgcaat tgttattact ttggcttttt
    20641 taattaagtt ttttatcttg taaaatttga gttcaaatgg tatatagtcc atatcacttg
    20701 aaaatatatc caaatctata tcaagaacaa actctgattc tacttctaaa tcaaatccat
    20761 atagactatc tattattatt aattctgaaa atatgttata ttttaaagca ggttttataa
    20821 aacttcctac atttaaaact tcatttgtat atctaaatac atcttttaga ttatttacat
    20881 ctacatcata gttctcaggt tctctagtat ccttatgttg gtctacatgc actaacttgc
    20941 atccttttgt aaactcaccc tttaacaaag attttgccca aaaataaaat gcatggttat
    21001 gattgtcaaa cacatatatc tttttatttc ccaggacata ttcgaccata ttctccaatc
    21061 cttttgcttt tatttcctta ttttcatcta cttcattaaa tactacctca ttgcctaacc
    21121 ttacatcatt taatgtacca tttattagtt ttggaacgta tatgctctta ttttctcttt
    21181 tatcatatga aaatacatta tttcctactg gtttttctat ataaaatcca ctatattcat
    21241 aattttccat aaaactttat ttcctccatt gttatataaa tatataagtt ataattttaa
    21301 aaattaaaat gcacttattg taaatcatat catctattat agaaaacatc ttatataact
    21361 aaatataata tcttctctca atatgtatta tacaataagt gcaaaatata tttatataaa
    21421 atatactaca ttcctataac aaaaccatca gcttcaattg gaaggtaact aactcttcta
    21481 ttcaactcca cctttccaaa aaatactacc caatatggtc taaaaatact ttcaatttta
    21541 actatttcaa tctctgggat tcctcccata aacctatgag ttaatctcat agccatttta
    21601 tttgcctttg cttttactct tcgttcgtcc ttatcactat actgcacaat attacaatcc
    21661 acatttttta caatttcata tgtaggaaaa tcttgtacta tactaccaga acctgtagaa
    21721 ccattcacta aaatttttaa ttcatttata tcattagaat atctcctatt cttgaaaatg
    21781 ggtttcgttt tgtgaatttt aagtgtgata attttaaact ctatataatg aagtctaact
    21841 tcatgagcat atttgttctt taatattagc ttactaaata aagaattttt tccactttta
    21901 gctatctcta tagcttcttc ttttgtaatt cttataggta acgctcttat atccataaaa
    21961 tcattctctt tcttattttt ttcttgtcat ttttaaaact ctatatatat aatcaaaaaa
    22021 tattacaatt acaactgaca taactccata tggaattatt tttccaacta taatatcatt
    22081 tctagtcaat ataccataaa atataaatcc tgttattaaa aagtacaata atactagaaa
    22141 accgtctatt ccaagccatt ttatttctaa atcttttttt accttagaca ctaatttaga
    22201 catagcagtt tctcctttta tagattattt tgtgtattta aattttcacc tattctatta
    22261 ccaatcatcc atgcaataaa tgaaaaaggt atagctatca caagaggctc taactcaaag
    22321 ctctgaactg gaaatatttt aaaataacca aaagtcactc caccaacaat cattcctaaa
    22381 ataccaccca tagatgttct tcttccattt ccaagaagcc cacctactat aggtacaaat
    22441 gccgaaccca tccaaatact tcctacaaat atacatgcat catatacatt ttcaaatcta
    22501 aatgctacgc taagccccat aactgctgct aaacatacac ctattctagt aaactttact
    22561 aattgtttct gagataactc tttttttgta attcttccat atatatcatt tgctaatgta
    22621 gccccagctg ctagataata gctatccaat gttgatatta tagaacctaa aattcctatt
    22681 ataaatatta ctcttattcc ttgtggtaat gtatctaaaa ctaaagttat atatccagca
    22741 gctggagcca tttctggata agtagctctt actataagtc ctgtcatagt taacaccatg
    22801 tcaaaacata tccatagtga aaaacaggtt aataaggctc ttcttccaac cttaggagaa
    22861 tctgctgctg aaaatctttg ataaaaagtt gggtctgaat aagctccaaa agaatataca
    22921 attaacatca atgctttcat agctgacata ccttttgtag ggtgcataag ctgtggtgca
    22981 tctttgagtg cttctgtaag accttgaaac cctcctattt gttcaaattg acctggcata
    23041 accatagtta aaccaaatac catacaaaaa aacaatacca tatctgtaat ggcaactccc
    23101 ataagcccac caagtactgt aagtacaacg actactccta ccattattaa tcctattaat
    23161 tctttatcta ttttccatgc tacgttacct atagttccca tagcagttat ttctccaagt
    23221 tgtgcacaat atataaacat caaaattgcc ccaattatag caacatgctt gccataaaaa
    23281 ctttccagta aatcaggaac tgttatattg gttcttatat gaatccttgg accaacccac
    23341 aatgctaaag gcattctccc aatatgtgca gctattgacc aaactgccca tgcagatatt
    23401 ccatatatag ccgcatactc tacactacct actgtaccaa ctcctccata ccatgatgca
    23461 accaaagttc ctactattaa ggaccatggt aaacttcgat ttcctaggta ataactttcc
    23521 atatctttta catttctaga aaaataataa cctattccta ataatataaa tgcaaatata
    23581 actataatcc cattttccca aaatgttaac atatctaatc tccacattct tatattttaa
    23641 tttttaactt taatatctaa atatgaacaa ctctacccat ttccataaaa ataggtagag
    23701 ttatataata attataagta tttaagtaat cttgttatta agcaatttta ttgtttaaac
    23761 ctttattttc tcttttattt attttattta aagcataagt agcaaatatc cctataactg
    23821 cacatactac agataaaata aatatatatg tatatcctgt ttgtccatat ttatctaacc
    23881 aattacctgc aatagtgtaa taaaacgcat ctggagaaaa tcctataaat gaagcaaatc
    23941 caactactgc tcctgtagtt tctaaagata tattagactc tgaaacagat gcaaagtata
    24001 tacctctaaa tccaaataaa attacactta gtattatcat gtttattaca gctatccata
    24061 taaatcctgt actcttagga ataaccaagt aagcagctgt acttactgtc attaatataa
    24121 atcctacaaa cattactctt atagatgaac caactttatc tgttataaca ccagcaactg
    24181 gagatgctcc catttttata acataagttc ttattattga taaagcagaa actagagtca
    24241 ttggcattac ataaacttct gataagtatg gacttaaata agttaaactt gagaatacta
    24301 aataagttga aaatattata agaccaatta accaagcctt tggcattgta actactttta
    24361 acaatgactt aatacttaat ccttcatctg atgctccact atcttttttc tcttctacta
    24421 agaaaaatag aagtatacca catattatag atgctgcaga atataaccat actacatatt
    24481 tgaatcctac tgttatttca gcaaatttac caaagaaata aagacctata aaagaaatta
    24541 atgtacctga tacgcctgat aacccttcat aaaaaccaaa tattcttcct tgctctgact
    24601 cacttccttg cattctaaca accttaacag aggctgagaa gaaggttaat attgtcgtaa
    24661 atccccataa tacaaatatt aaaagtatca tactatatga tgggaatgta gagaaataaa
    24721 atccaagtat tcctgaagca attaaagaaa aagttattaa ttttctaact gagaatctat
    24781 ctgcaaacca tcctcctata aaataagata ccattcctac taatccatat aaactcaata
    24841 agttccctat ttgtgtatga cttaatgcta aagcttgttg cattgggtca taaaatgatg
    24901 atttcatata tggtaaacta tacatagctg ttgttccaaa tgccaatatg aatattatca
    24961 aaaatctttt aacattattt ttgctttcca ttgattctct ctccttaaaa ttttattgtt
    25021 tataatctca ttcatataat tttattttaa tttttctatt gcttgtttaa aatcatttat
    25081 tatatcattt gaagattcta atcctacagc tattcttatt agattttccc cattcatttg
    25141 aactaatgta tgctcttccc ctaagcttgt tgctattgtt gcaagctcta aagaattcat
    25201 taatcttcta ctagcttggt ctcttgtcaa tccattgata ccatccttaa gtttaaatga
    25261 aactacacct ccacctaaac cattcatttg agttttacaa agctcatatt gaggatgaga
    25321 ttttaatgct ggatacttta ccaattccac attctcttct tcctctaaaa attctgctac
    25381 tgctaatcca ttttcacaat gctttttcat cctcatatct aacgttttca taccccttaa
    25441 aatcatccat gcactcattg gtggtaaaga tgctcctgta aaacaacata aacttggcca
    25501 tctaactaaa tctattaatt cttttgaacc tgctactgct ccccctaaag tatccccatg
    25561 tccatttata aacttagtaa gactatgtat tactaaatct gcacctaaat ctattggtct
    25621 ttgtacaatt ggtgtcccaa aagtactatc aactatagct aagcttttat tttcatgagc
    25681 aatttctgct attgttttta tatctactaa gtctaatgat ggatttaaag gactttctat
    25741 ataaactatt ttagtatttg gtctcattgc ttcttttaca ttttgtggat ttactgcatc
    25801 tacaaatgta acttcaactc caaatttaga taacaactca gacatgaata atttagtgtg
    25861 tgaaaatatt ccatctgaac taactatatg gtcaccactt tttaccaatg ctaatatagt
    25921 agaggttatt gcccccatcc ctgatgtact agatatggca ctttctgcat tttcaagcat
    25981 agccaactta gcttctaact ctgtaagagt aggattacac tctcttgtat acacatatcc
    26041 ccatgtcata cacaactctt caaaatgctc tactgtcttt gcagcaaatg ttgctgtttg
    26101 acatattggt gtagccaatg cacctgttgt tgggtctgca ctatgtcccc aatgtattat
    26161 ttttgtctct aaattttgat taatattgtt actcattttg atttcctccc attttgactt
    26221 atttatacaa cgttttccct gccaaatttc atcaatttag cttagtctta atacattttt
    26281 tcaagtatac ttttttattt gttataattt ctaaaaatat gacacttatt ttgttttttt
    26341 acagttctaa ttataaactc tatagtaact atagagtcaa tatgtttttg atattttttt
    26401 tacaatgttt aaaatagtca atacaaaaat aggtatatct tagaataact aaagtcatcc
    26461 taagatatac ctatttttat atcacaatat aaataattac atataagcat tagttttttt
    26521 atcataaata gatttttcaa gatttatcat tttttcataa atatattata gttaaatatt
    26581 ttaatattac ctaacatcta caataaaata tactcttaaa ataaaattat ataattaaaa
    26641 atactctata aaagctaaaa agtttttcta ttcgctacat ctaaaaataa ttagatagag
    26701 gtataaatgt atttagttta tttatacctc tagtctttta taaattatat ctctactaaa
    26761 ttgatttttt agcacgaata agtgtgctct tggagatacc agtcatcttc acaacctctc
    26821 tatatggctt agaatttaat aaccccaatg catattgtat ctgttgattg ctgtatttct
    26881 ttggcctacc atctttaaag tcctttttct ttttagcaaa ttcttttcct aattgagtac
    26941 gttctattat catatttctc tcaagttctg caactgcaag taatgtagtc aaaaagaatt
    27001 tacccattga agtattttct aaaaggccta tatttaaaat atgaacactt acttctttag
    27061 caaataaacc ttctattagt tgtattcctt ctgatgtact tctagctagt ctatccagct
    27121 tagttgcaac aagtaagtct ccctttttta gagatgatat aattttttca aatttaggcc
    27181 tgtttgtagt agtgcctgta taagtttcct ttattatttt agcatcatta tatttattca
    27241 aaatttcttg ctgttgctga tacaaactgt tgttgtctgt ttgatttttt gtacttacac
    27301 ggcaatatcc atatataata atcatcactt cctaacataa agattttgta cagaagttac
    27361 ccagaagctt gtttttactt atctttatcc attttactaa aacgattttt gggtgtcaat
    27421 actgttaact tttgacacca taataattcc tttataattt gtttgactat gtcaaaaatt
    27481 accaatataa tgaaattaat gagtttatac aaattggagg aaataatatg aatagtctgt
    27541 taaaagaagc aatagatgaa ttaaaaaaca tccattgcgg ggaagttttt ttattaaaag
    27601 aattgttcaa aggctatgaa tggaacaggt tggagatgaa tatcagattg aaattaggaa
    27661 aacttttttt gtatgaagtg gtaactaatc ccaatttaaa tgtagaggtc atcaataaaa
    27721 attctgctta tcagcaaatg tataaaaaaa aatagtgact taaatgtata taatagtata
    27781 atcttcttat tgattcaaaa gttaaaactt ttaatacaaa acaatcattc tattttaaca
    27841 tttatcaata tgtctaaatt tatataatta acacatacga atagtattgt ttaaatcaca
    27901 ttatttaaga tagataaatc ttaaccctac tccagcataa atactaaaat agggcttaga
    27961 attatctata tttttatccc ataaaatgct tagctcttcc tcttgattga acatatatat
    28021 ctggggaaat acaatagaag cgtaaattta taaaatttcc aaagtcagaa aacttcagtt
    28081 caaacttagg tataccaaaa ctttcaggtg ctatttcgtc aacaccaaaa tagattataa
    28141 ttccattatc tgtaagataa aatgcttggt cttcaggtat aactaactca acattagaat
    28201 aatacatttc tctattttca tttatttgag atttaatgta atcagtaatt atattaatat
    28261 aatcaactcc atctctaaaa atgtcattaa gtaaaagttc ttttccagtt gtcaaatcta
    28321 tattgtaatt attcaatgta ttgtatttag gcccatagtt attagcaaac cccataaggt
    28381 ttaatatcat actcagtaca taatttttat taaaagtaac tgcgtaactg gtagataccc
    28441 aatagctttg ttttggaagt gaattttgag gagctgcgtt attatattct cgttcttctt
    28501 cctgtaagcc atttttaaaa ttatttacag tcattcttac agcattgttt atgttattta
    28561 aaataactgg gtttacatac gtggattgat ttctaatatt gtatataaca ggatacttta
    28621 catcatatga aaaatactta cttctttcaa aatcttcatt aaattgtaca tataatatat
    28681 tatatgtaca ggtatttgta gattgataat tttccattaa aatcctcccc cttttataaa
    28741 aaaatcagat acaatataat atgcttaaaa cagtaataat gttaatggta aatgtaaaga
    28801 atagaaagta tctaaaacag caaaaaatga ctaattttgt ggtataatac ataggattga
    28861 gagttatttt ataggaggaa aaatatgtta ttattagcag ataaatggaa agattatgaa
    28921 cttatagata tgggaaatgg agaaaaatta gaacgttggg gaagttatgt acttagaaga
    28981 ccagacccac aggttgtatg gccaatggaa tctgaatggg ctttatggaa aaaccctcat
    29041 ggacattatc acagaagcaa taaaggtgga ggtcaatggg aacacaaaaa aagatatcca
    29101 gaacaatgga ctataaatta taaaaactta aagtttcaca ttaaaccaac tggctttaaa
    29161 catactggat tattcccaga gcaagcagct aactgggatt ggatgataga gaaaataaag
    29221 aaagctaaca gacctataaa agtgttgaat ctttttgcat atacaggtgg agctactgta
    29281 gcatgtgcat ctgctggtgc agaagtatgt catgttgatg ctgcaaaagg tatggttaat
    29341 tgggcaaaag aaaatataga attatcaggt cttaaaaatc aaacagtaag atttatagtg
    29401 gatgatgttg taaagtttgt tgaaagagaa ataagaagag gtaaaaaata tgatgcaata
    29461 ataatggacc ctccttctta tggaagaggt cctaaaggag aagtatggca aatagaagaa
    29521 aagttataca gttttgtaga tttatgtatg ggagttttat cagataaccc tttatttttc
    29581 ttaattaatt cttatacaac aggattttct ccaatagttc ttgaaaatgt attgtctaca
    29641 acaataggta aaaagacaaa tacaggagat atatacggtg gggaattagg aataccagct
    29701 tccagagatg gtaagatact tccttgtggt atatttggaa gatgggagaa aaaataatga
    29761 taaaagtcat atatgaagat aaccatttat tagttgtaga aaaaccagtt aacatattgt
    29821 ctcaaggaga taatactaat gataaagata tggtaaatct tttaaaagac tatattaaaa
    29881 aaaagtataa caaacctgga aatgtatata ttggtttaat acatagattg gatagaccag
    29941 taggtggagt tatggtgttt gcaaaaacat caaaagcagc atctagattg tctgagcagg
    30001 taagaagtaa gactttcaaa aaaacttatc tagctgttgt tcatggcaag ataaaatcta
    30061 actcagatat actaaaagat tttttatata aaaataaaaa aactaatatg gtaactgtag
    30121 tgaaaaaaag ccataaagat gccaaagaag ctgaacttaa ctataatgta ttagatttta
    30181 aagaaaatct aagtttagtt caagttaatt taaagactgg tcgttctcat caaataagag
    30241 ttcaatttgc aagcagaaaa catccattat acggagacca aagatatggc aaagaaataa
    30301 ataagattgg acaacaaata tctctttggt ccaataagat agaaatttgc catcctacta
    30361 caaaagaaaa aatggaattt acatgtcatc cacctgacaa atatccatgg aatatatttt
    30421 aaatctcaaa tgaggtgatt atatgagtaa aaaattttca ataggagaaa tgtctaaact
    30481 tcataaaata agcatacaga cactaagata ctatgaccaa atagatttat ttaaacctgt
    30541 tcatgttgac caagaaagca attacagata ttactcaatt gaccaatttt cacaattaga
    30601 tattataaaa tatttaaaat atttaggtat gcctttaaaa gaaattaagt caaagcttga
    30661 tgaaaataat gaagaaattc taaaattact aacaaataaa attaatatag tggatgaaaa
    30721 aattaaagaa ttagagctta taaagaaggt actaagcaca aagaaagaaa ctatggaaaa
    30781 aggtatgaaa gtagatgaag ttggtaaaat agtgagaaaa catattccac gaagaagtat
    30841 cttatctata gagtatgaaa aaggattaag tagtgaagaa actatggaac tttccagaag
    30901 acaaatagca aatatattag aagataatat atctgtgttc tatggtggag taagtggact
    30961 tgtatctata gataaatttt taaaagaaga taaagttatt tatgacaata gttttgttac
    31021 tgttgaaaga gacttatttg atataaaatc acaaaaacat ataacagaaa tttcatctgg
    31081 tgattttatt tgtatgacat ataaagggcc ttacaaagaa aattataccg cttttaagaa
    31141 actggttgat tatgttgaat ataaaagaat acctattgaa aattatatat atgaaatacc
    31201 tataatagac cctctgtcta caaacaacga agaggaactt ctaacagaaa ttcaaataca
    31261 agttaaaaag agagaaattg acttaagatg tctagtgtag taatctagtt tacttacaca
    31321 tcttaatata gttgtctatt atcaacatat gatttttcta gatagtgatt cctaacagtg
    31381 agattttcaa aaaataggag gaaatatggc taatgctaat tccctcctat ttttaattaa
    31441 tccatatcat tttaattaag ccatgtcatc acgaagtgca tcaataatat tttctttttt
    31501 tatcttatta atagtataca acattgtaat aaatactata aataaaacac taaatatact
    31561 aattccaata ctaaaccatg gaatcacaaa atcaatatca tctgtaacca ttactttatg
    31621 aattagccat gaagaaatta ctgctatagg aagtccaaag aacaatgctc tcatgccata
    31681 aaaggcacac tcaaaattca tcatcttttg gaaatcatgc tcagacattc ctacagagcg
    31741 aagcatggca agttctctac gacgtaactt aatattagtt gaaattgtat taaacacatt
    31801 ggcaatcgaa atcagagaaa tcataattat gaaagtatag gcaaaaacat tggcaataaa
    31861 aatgtaatta cggttctcat ccatcattcc atacatattg tacagattgt actcattcgt
    31921 aactccctca ctctcaataa tttgctccat ttctgcaact gactgagtag gatttttcga
    31981 ttgaaagctt aaactttcaa ttcctgtaga aacaccagga atctcaaact tatctttggc
    32041 tgaataagga gccaatactc tgaagcttgc tttcttcaca tctgaacttc tgattcctgg
    32101 aggagaatca ggtggcacta ctttgacaaa tgaaatattc acattttgtc tctcaggtat
    32161 ctccaacttg ccattagttt caggagtgag gctaacattc atagaagaac tgttgaaaat
    32221 atcaataata ttattatcct ttgttaccat agaaacagca atcagttttg cattttgtcc
    32281 agtatattct tctgctggta atccaagact tttaataata ttcagataag ttctatcatc
    32341 aagaaattgc atatctactg gtaattcaag catttcactc atagaatgtg aaccctcata
    32401 gttcaaataa tcgtctgtaa gctcacttac tttggcaaca catgaatagg tcataagttt
    32461 ctgatacaaa ccttcgtaaa caccatttgc agtttttagc ttatcgtaaa gcttcaacat
    32521 ttcgttgtct ttcatacctt gtgtagaaaa aataatatcc tggtcagtaa cctctgacct
    32581 ctgatttgac atctgtttta ggtctgctac taaagcactt gtagatataa atagaactat
    32641 gcttaaaaca agcgacaata caatacttcg ataacgtttc ttgtttcttt taaagttttt
    32701 catagcaaga actccctcaa gaccataaac tcgctgtgtt agttttgatg tcttcacaga
    32761 tttagattca atttttacct catttgtctg acgaatacac tccatcactg gtgtgttggc
    32821 agcctttctt gctggtatgt aagcagaaat taagattgta accatactta ccactgctgc
    32881 aacgatgatt gcagggatag acaatgttaa tgtcaacgga acgtttacat agagaatatt
    32941 tgcaaagttt ttagctatga cagaaatcac aagtccaata ctgactatac cgattgcaac
    33001 accaattggt ataccaatcg caccaatgca aattccttca aatagcaccg aatttcgtaa
    33061 ctgttttgct gtagctccaa cagatgaaag tattccaaat tgatgtgttc gctcgttcaa
    33121 tgacatgtta aatgaattat atattagaaa aattgagcct agcatgatta tggcaagcac
    33181 aatgccacca accgagtaca aaaacatatt gaacaaattg ttatcagaaa cacctatgaa
    33241 gcgcaacaca ttgtcattga aaatggaagc atggtcttta gtgctactta tgtaagagcg
    33301 aatctgatgt ggatttttca atgtgacaaa aaggctaaga ctgtcagtct tgacttgttt
    33361 atcttctttg gttatcaagg tatatcctgg tgcagaagat tcttcaaata cgggctttct
    33421 acagataccc acaactgtat aagttttctt atcctgtggc acaaaaactt cactcccagc
    33481 agtgtatggg tcactctgac caagcttttc attttcactc attcgtttcc ctacatccaa
    33541 agaaatagta tcacctactg caaatttgac accaccatct gtcgcaactt tacttgaaac
    33601 aagaatctct ctactatttt caggtaatct tccagaaatt aaagttatag gcaaagtatc
    33661 aaaagcttct ttgctaaatc cagcaataaa aagatatggt ttatctggat ttctgttacc
    33721 ttcaagtgtt gcatagccaa tattttcaaa tgttgcagta tttgcaactt catcattgac
    33781 tctttgttcc tgtacaaaag aagaatccac atccaaaaac tggacatgcc aatcaccata
    33841 ttttataata gctccatttg tcatatagtt catcaaagaa actccaaagg tagtaactgc
    33901 tgtaatcata gcagctgaca gaacaactcc tataattgtt acaagagttc gagtgcgatt
    33961 ctttttcaat ccttgcagag caactttgtt aaaaatgttc attaacgatt caccttcctc
    34021 tcatcacgca ctacttttcc atctgaaata cagataattc tatctgcttg taaagcaatg
    34081 ttttcatcat gtgtgacaat aatgagagtt tggtgatatt tactatggct ctctttcagt
    34141 aactggataa tctcttgtcc atttttactg tctaagctac ctgtaggctc atcagcaagc
    34201 ataactgctg gtgcattcat caatgcacga ccaatggcaa cacgttgctg ttggccacca
    34261 gaaagttgat ttggtaaatg tgtttttcgt tcttttaaac caagtaattc taacaagtca
    34321 tttaaccgtt cttgattgac cttacgttta tccataagta taggcaatgt gatattttcc
    34381 actacattta atgtgggtat cagattgtga aactgataaa tcaatccaac ttgtcgccta
    34441 cgaaaaatag caagtttttc attgctttgg ccatatacat cttgcccctc cagatatatc
    34501 tttccacttg ttggtacgtc tactcctgca atggaatgta gtagtgtaga tttaccagaa
    34561 ccagaagaac caatgattgc agtaaactcc cctttttcaa tagtaagtga gacatggtca
    34621 agtgcagtaa ccttattttc attcttacca taaaccttac ataaatcttc aatctttaaa
    34681 aacgccatta tataagtctc ctttcatatt ttataaatat atcataggac tttcaactta
    34741 catttaagtg acatttaaat gagagattcg tcactttgga aaacgaataa caaatattgc
    34801 accaccttgt gggtgatttt gtgcagtaat tgttcctcct tgtctcataa taatcgtctt
    34861 acaaagtgcc aatcctattc cataaccagc tgtgcttgaa tttttcccac gataaaatct
    34921 gttaaataga catggtaagt cttctttttt aaagcctgct ccgttgtcat gaatagtaag
    34981 ttgagtaaac aaaaagttgt cctcacaaat gatatcaatt tttccattat cacccacact
    35041 ctccatgcag tttttaaata tattttgaat tgcttctgaa agccaattta aatcacccaa
    35101 aatccttact ccttttggta tatcaatatg taaagtgata ttgtgcagtt ccataggaat
    35161 caaaagttga tgaagtgcag aactaatcaa attattcaca tcaatttgtt ctttttgaaa
    35221 gactacaata cctgcatcta aacgtgataa ttttaaaagg gaagtaatca gccagtccat
    35281 tcgtataagt aattcctctg tttctcgtat caactctttt ctctcatctt catcagaagt
    35341 attctctaac agtgacaaaa taagagttac tgatgtaaga ggagtgcgaa gctggtgggc
    35401 tatgtcagct agtgagtcag caaggtgttc tttttctttt ttcagtgcgt aattttgctc
    35461 tctaatacgt aacgtcattt tagttatttc actttgtaga atagaaagct caccctcatc
    35521 tgattcagca atatacagat ggttagcatt atgaagcaca agattaattt gttctgaaat
    35581 ctgtgcaata cttttgtatc gatttttagt aaacacaaaa aatgctattc caaaggtagt
    35641 ggcagaaaca atagaaagta ttccagtcat aatactgatt gcaaatccca gggctacagt
    35701 gagaatagta attaataaga ataaaatagc aagttttcga aactctctat ttcgaaacat
    35761 aacttccccc caatctatac cctgtcccac gaacagtcaa aattatttgt ggacttgaag
    35821 ggtcatcttc tatcttctct cgcaagcgtt tgatgtacac agtcaatgtg ttgtcattaa
    35881 caaactcacc tgccgcatcc cacaattcat caagtaatct taccctcgta ataatacttt
    35941 taggattgct aataaacacc aataacaaac ggtattctaa agctgaaaga aaaacctcat
    36001 tgccattctt tttcacaaca ccggttgctg tatctacata aagcccacaa atttcaaaag
    36061 ttgacccaaa acgcccactt tttcgtagtg ctgttctaat tcgcgcaatc agttcacgtg
    36121 gacgaaaagg tttagtaata taatcatctg cacccatatt cagtccagta acaacacttg
    36181 attcatcacc ggaagctgtc aaaaagataa caggaatgtc ttgcttttct ttgatttctg
    36241 tgcaaatcgt aaacccattt ccatcaggta aagaaatatc aataagtgcc aaatcaaatt
    36301 tattcttagc aatctctaca agtgcttcac ttcttgtgga tacatgggtt actataaatc
    36361 cttctgaatt aagcaaaaga ataagatttt tggcaattgc tttatcatcc tcaactaaaa
    36421 atatccgttt catttacttt catcctcctt tattttatta gttttatata ttccagcaga
    36481 gcaatagtac actactattt tacttatcat tacacaattt tcagtagttt cttttgttct
    36541 tatataatcc atgcataata cctccattga tttattatat ttcttataac ataaatacac
    36601 aagataagac aaaaaacata atgtaagtgc aagtttttta actcactaac ttataaacat
    36661 acactcctac taacactact ttcttgatga cacatcttac aagcttatat tcatacatca
    36721 atgaaaaatt aaatttatcc atttattaaa ataaaaggca atagcttcta tagctaatgc
    36781 cctttatctt aaaatgattt aaatactata caatttttat aaatggctat aaataaactc
    36841 atatagaata taaaatttat ctacagtctt ttgttataca aaatttataa cctcttatag
    36901 aacaaattta ccactttgca aacttatcac ttttactcag ctatattata aacttttaat
    36961 ttatctttgt ttaaatgttt cttcttaact tctactaaag cttttagcgt atccagagat
    37021 gtcattattt cagtagaaaa ttcaatagct gttcttctca ttttaaagcc atctcttgta
    37081 gagtcatttc ctttagttgg tgtatttatt actatatcaa cttgtttatt tcttatagca
    37141 tctaatatgt ttggtctagg ttcttcaatt ctatttacta tatcagcctc tattccattt
    37201 tctcttaaac tctt
//
LOCUS       DAEOTL010000036        36995 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEOTL010000036 DAEOTL010000000
VERSION     DAEOTL010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.036"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            141..1139
                     /locus_tag="KRH82_002098"
     CDS             141..1139
                     /locus_tag="KRH82_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBG8655377.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            1501..2028
                     /locus_tag="KRH82_002099"
     CDS             1501..2028
                     /locus_tag="KRH82_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBG8655378.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            2055..2651
                     /locus_tag="KRH82_002100"
     CDS             2055..2651
                     /locus_tag="KRH82_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBG8655379.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFAKDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(2730..4313)
                     /gene="asnB"
                     /locus_tag="KRH82_002101"
     CDS             complement(2730..4313)
                     /gene="asnB"
                     /locus_tag="KRH82_002101"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBG8655380.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(4915..5751)
                     /locus_tag="KRH82_002102"
     CDS             complement(4915..5751)
                     /locus_tag="KRH82_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8655381.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(5775..7241)
                     /locus_tag="KRH82_002103"
     CDS             complement(5775..7241)
                     /locus_tag="KRH82_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBG8655382.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICEIYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(7244..9106)
                     /locus_tag="KRH82_002104"
     CDS             complement(7244..9106)
                     /locus_tag="KRH82_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8655383.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(9353..10216)
                     /locus_tag="KRH82_002105"
     CDS             complement(9353..10216)
                     /locus_tag="KRH82_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBG8655384.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(10270..11202)
                     /locus_tag="KRH82_002106"
     CDS             complement(10270..11202)
                     /locus_tag="KRH82_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBG8655385.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(11288..11839)
                     /locus_tag="KRH82_002107"
     CDS             complement(11288..11839)
                     /locus_tag="KRH82_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655386.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(12068..12559)
                     /locus_tag="KRH82_002108"
     CDS             complement(12068..12559)
                     /locus_tag="KRH82_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655387.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(12587..13147)
                     /locus_tag="KRH82_002109"
     CDS             complement(12587..13147)
                     /locus_tag="KRH82_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBG8655388.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(13299..14456)
                     /locus_tag="KRH82_002110"
     CDS             complement(13299..14456)
                     /locus_tag="KRH82_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBG8655389.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(14493..15434)
                     /locus_tag="KRH82_002111"
     CDS             complement(14493..15434)
                     /locus_tag="KRH82_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655390.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(15521..16213)
                     /locus_tag="KRH82_002112"
     CDS             complement(15521..16213)
                     /locus_tag="KRH82_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8655391.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVEEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(16322..17134)
                     /locus_tag="KRH82_002113"
     CDS             complement(16322..17134)
                     /locus_tag="KRH82_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBG8655392.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(17185..18096)
                     /locus_tag="KRH82_002114"
     CDS             complement(17185..18096)
                     /locus_tag="KRH82_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8655393.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEIFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(18155..18886)
                     /locus_tag="KRH82_002115"
     CDS             complement(18155..18886)
                     /locus_tag="KRH82_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBG8655394.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            18975..19226
                     /locus_tag="KRH82_002116"
     CDS             18975..19226
                     /locus_tag="KRH82_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655395.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            19459..19878
                     /locus_tag="KRH82_002117"
     CDS             19459..19878
                     /locus_tag="KRH82_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655396.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVSDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            19903..24960
                     /locus_tag="KRH82_002118"
     CDS             19903..24960
                     /locus_tag="KRH82_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBG8655397.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNHENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(25145..25882)
                     /locus_tag="KRH82_002119"
     CDS             complement(25145..25882)
                     /locus_tag="KRH82_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655398.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(25901..26836)
                     /locus_tag="KRH82_002120"
     CDS             complement(25901..26836)
                     /locus_tag="KRH82_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBG8655399.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            27044..29620
                     /locus_tag="KRH82_002121"
     CDS             27044..29620
                     /locus_tag="KRH82_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8655400.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGTDHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YANKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKRGQCEIFSNLNESELNNFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYIAIAMSLFAGIVIYSIYVISIYQRVQEYGILR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIMLIISFFTYLKIRRISPIDAIRKTFGSDKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFMIIVLSMSIGGIIVIKDNYKYSFLDVQNKSVQEQTYM
                     NADFILSNVYLNETGNNTSFKDIKGFSDSQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPNGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDSVDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGLI
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            29632..30303
                     /locus_tag="KRH82_002122"
     CDS             29632..30303
                     /locus_tag="KRH82_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655401.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVAGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIEDLINLLGLKERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            30330..30671
                     /locus_tag="KRH82_002123"
     CDS             30330..30671
                     /locus_tag="KRH82_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655402.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIVNIKNQN
                     EKVILNKSIKK"
     gene            complement(31031..33673)
                     /gene="adhE"
                     /locus_tag="KRH82_002124"
                     /gene_synonym="adhC"
     CDS             complement(31031..33673)
                     /gene="adhE"
                     /locus_tag="KRH82_002124"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBG8655403.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            34551..36149
                     /locus_tag="KRH82_002125"
     CDS             34551..36149
                     /locus_tag="KRH82_002125"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBG8655404.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(36384..>36995)
                     /locus_tag="KRH82_002126"
     CDS             complement(36384..>36995)
                     /locus_tag="KRH82_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HBG8655405.1"
                     /translation="GPTGNTGVTGEIGLTGATGPTGNTGATGSIGPTGVTGPTGATGV
                     TGPTGPTGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIGNSSSITVDANGTFT
                     VQENGVYYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTTEPGGGGVLSGYFAG
                     FLFGGTTFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT        12991 a         5804 c         4606 g        13594 t
ORIGIN      
        1 aaataacaca gggaaaacaa tttcaaaact aaatttttaa ccttaaaaat tttgtataaa
       61 aaatataacc ttatatgcta catattattt ctaaatgaaa aattaccata ataatttaat
      121 aattacagga gggtattgat atgaaaatac tagtatttgg agcacgcgat tatgaagaac
      181 cagtaataaa aaaatggtct gaagaacata aggatgttca agtggatatt tatcctgaaa
      241 acatgactga agaaaatgta gttaaagcta aagggtatga tggtatatct atacaacaaa
      301 ctaactatat agataatcct tatatttatg aaactttaaa agatgctggg gttaaagtta
      361 tagcttcaag aactgcaggg gttgacatga tacattttga tttagttaat gaaaatggac
      421 ttatcgttac aaacgttcct tcttattcac ctaatgcaat agctgaatta gctgttactc
      481 aagctatgaa ccttttaaga aagactcctc tagtaaagaa aaaagtctgt gaaggtgatt
      541 accgttggat agctgaactt cttggaacag aagttagatc tattacagtt ggtgttatag
      601 gtacaggaaa aataggtgct acttctgcaa aattattcaa aggcctagga gctaatgtaa
      661 ttgcatttga ccaatatcca aatagtgatt taaatgatat attaacttac aaagattctt
      721 tagaagacct tctaaaagaa gctgacctta taacattaca tactccttta cttgaaggaa
      781 caaaacatat gataaataaa gatactctag ctataatgaa ggatggagct tacatagtaa
      841 atactggccg tggtggttta attaatacag gggatttaat agaagcacta gagtcaggaa
      901 aaattagagc tgctgccctt gatacatttg aaactgaagg attgttctta aacaaaaaaa
      961 tgaatcctgg agaattaact gacccagaaa taaataaact tctttctatg gaacaagtta
     1021 tattcactca tcaccttggt ttcttcacta gtacagcgat tgaaaatata gtttattcta
     1081 gtttaagcag tgctgtagaa gttataaaaa caggaactgc tactaataga gtaaattagt
     1141 attttataaa tatatttttt cattaattag ctattatcta acaaaatagc ctttaatttc
     1201 ccaaatataa gagagtcagc tcagtatata ttgagtagac tctcttatat tattttttat
     1261 attaaacttg tactcttctt attcatacca aattaaattt atattaactt attctaacta
     1321 ctcctactct atacatttta cctattttta cttttctaat tatatacatt tgaatgggta
     1381 caatctgtat tttacaaaaa aaacacctaa caaactatga aaattgtatg attaatatta
     1441 atatatttat aagaaaacat aacaattatg ttagctctgg atttttaggg agggagtata
     1501 ttggaaaaaa tgaataaagt tacttctaaa aaaactacct atattgttac ttcagcatta
     1561 tttgcatcca taatatgcct gacaatagca tatatattac atattccagt tggtggaaac
     1621 aatggatatg ttcatatagg agatgctttt atttatctag ctgcaactat tttgccaaca
     1681 aactatgcta tagctgcttc tgcaattggt gctggtctag ctgatttatc tacaggtgct
     1741 gctatctggg taataccaac tataatcata aaaccaatac ttgtattatt tttcacttct
     1801 aaaagtgaca agataataaa taagagaaat atagttgctt cggttgtagc aggtatagta
     1861 ggattagttt tatacatgtt tgctgaaggt ataattattg gaagttttac aagtgcattt
     1921 gtaatgagct tacttggctt attacagcca ataggaagtt ttattgtttt tataatctta
     1981 ggtatggcac ttgataaact tgattttaaa aaacgttatt ttaattaaga atttaaattt
     2041 atggagggaa aattatgaat atcttatata caattgaaaa tagtatctat gtaaatataa
     2101 ctaatacatg tccatgtagt tgtgtttttt gtataagaaa cgaaaaagat gaagttgcaa
     2161 atagtggtag tttatggctg gaacatgagc caagtgtaga tgaagtaaaa gaagccttca
     2221 ataaatacaa tttagacgac tatgatgaaa tcgtattttg tggatatggc gaaccattaa
     2281 tgagaataaa tgaattgata gaggtagcaa agtttataaa agaaaaaagt agcataaaga
     2341 taagaataaa tacaaatggt ctaagtgatt taatacataa caaaaaaaca gctattctgt
     2401 taaaaaatgt tatagatgca gtatcaataa gtcttaatgc cccaaataaa gaagcttata
     2461 atagagttac tcaaccaaag tttggagaaa aatcatttga ttatatgtta gattttgcaa
     2521 aagattgcaa aaaatatata aaagaagtag ctttttcagt agtagatgaa atatctccag
     2581 aagaaataga agaatctaaa caactggcaa aaaaacttga tataccatta agggttagac
     2641 ataagaatta gcaagtaaaa ttataaaaca ttaattataa aacattaaga atcacctgaa
     2701 tggtctttca ggtgattctt cctcttgtat taacatttta caaaatagat ttcataccac
     2761 actaggaatg tgtaaatcat ccaaatcttt ctccaattat cagagtttcc actaatgtag
     2821 tcattaaaaa tctcattaat ctcatctatg ttaaagaatt tatctgctat ctcactattg
     2881 aatttatctc ggatgtcctt attatattgg tcatcagcca tccatatacg aattggcaca
     2941 ataaatccta atttatttct aaaagcaatc tcttctggta atgtttttga tgcagctgta
     3001 cgaaaggcaa tcttattctc ttttcctttc actttatatt ctgatggtat tctggatgca
     3061 atatcaaata ttcttgtatc tgtaagaggc attctgactt ccaatccaac tgcagtactc
     3121 attttatcta tattaaaata aatatctcct tccaaccata tttgaatatc tacatttgac
     3181 atgttagtaa gtgtatctag ttcttctgtt tcttcataaa ttccctttac cacttcaata
     3241 ggaagcacat caggattgta tttcttaaga atttttcttt tctcaccctc attcataatg
     3301 tttgtatttc caatataaaa tgtcttcaaa ttctctccat aacactctgc cttatggtat
     3361 atattatatc caccaaaaaa ctcatctgct ccttctccag agtaacagat atttgtgttt
     3421 tcagctgctg ccttgcatcc aatagcaaaa acgatagcag atgcatctcc agttggttgc
     3481 tccatatggt acattacata aggtactgac gcaaaatact cttcaggtgt aattatatat
     3541 ctcgaatttt tacacccaag aatattagct gtctgttgtg ctaattttga ttcatcaaaa
     3601 cgctcttcct cataaccaca tgaacctgtt ttttctatat ctgacattgc caatatataa
     3661 gatgaatcaa cacctcctga taggaataac tctgcagttt cattctctga ttttacctct
     3721 ggcataattt tctgaagtgt tgtatgaatt tcatccgtcc attcctcaat agacttgctg
     3781 tggtcaggat gaaattcagg tttccaataa cgaccaatac atactgtttt attctgatag
     3841 acaaggtaat gtcctggcat aagcttcttt actccacgga agaatgtatt ttcacctgct
     3901 acatatgtga aagacatata aatctgtaac atgtcttcat ttaactcttt cacaaatcct
     3961 ggttgctcca taatcttacg aatagatgaa ccatagagaa gcttcccatt ttcagtctca
     4021 taataataga aaggttttac tccaaactgg tctcttaggc agaagagttt cttttccaca
     4081 gtatcccata atgcaaaagc aaacattcca tgcatgtgat ttgccatatc atatccccat
     4141 gtcttatatg cttccactaa aattgctcgt tcacgctcat ctctacataa tgaagaatcg
     4201 attccaagtt cttcacagag aactttccag tttcgaatat gtccattgta ttctagaatt
     4261 tttatcatat atgtgtcttt tcgtgttaaa tacttttctt ctaaatttat catatgtgta
     4321 tcctttcgta ttaaaacatt taacttctaa atttattaaa tgtttatata tatttattca
     4381 cttataatca ctgaaaaatc gacttttttc aaagtaaatt ctttttgaat tagtactaat
     4441 ctgctcttta ttaatggcat caatatgatt atcaagtatt atcagtgtta taacactgaa
     4501 ttttttattc ttcataaata ttgctccctt tatattacca actaaatata atatatctta
     4561 tgttacttac atattcttta agaaattctg aagattttat aaagtttttt gtattataat
     4621 caattaaaaa taaaattcta gttataaagc atattttcca ttaaacaaaa aaatagttaa
     4681 aataaattca taactacata aacttatttt aactatttgt atattttaat tataaatatt
     4741 aacttaaatt tttaacagga tacactcata aaataaacat aatgaacaac aaaataatat
     4801 gtctcagttt ctttatacac tttaccttct ttcaattttc taccatgtag acgtacaaga
     4861 taatattagt aattcactct attgctgtaa tttactctat tgctgtaatt cactctattg
     4921 cttaactcgt gcgatatgga caaccaagaa agctatttcc tcatttgtta acttttttcc
     4981 atatttcttt tctaaaaaat ctctaacttt taatgcaatt aacatttctt ttggatttga
     5041 ccttttcatt tgattaaata ataaatcatc accactgctt aacatactat ctgaaaaaaa
     5101 tctttccaca aaaaatttta tatgtgttat aaatctcata taatgcatac tctttttatc
     5161 taaggttcta ttcaaagaaa aaacaaaaat attaattatt tctccaatta ctttggcata
     5221 cttaatcgta tcatatgaat ttccatctga agccatagca tttgcaaaat ggaaagcaat
     5281 gttagctgct tcttcctctg gtaattgaat gcccaatctc tcctctacca tataaattgc
     5341 aaccattcca accttaaact catttggata ataatttttt atttcccaaa atactcgatt
     5401 tgtaattttt attcctttac gcatcctttc aattgcaaag ttaaaatggt ctgctaatat
     5461 taagtataag tttttattaa aagatgagtt caataacttt tctgcctcta ctattatttc
     5521 ctgtgttatc tttaaaatgt cgacaggaat atcatccatt aattctaaaa attgttttga
     5581 ttttgtattt tcaacaggga caaacatttg attatcattg gaaccacaaa tatattctcc
     5641 tgttttttta ccatatccaa ttcctttccc tagcaaaata aattcattat cctttgtgtc
     5701 atgaactaaa acaacgctcg agttcaaaac tttctttatt atgtagttca ttttatttgc
     5761 tcaccttcta ttggtcattt aaaatctata ctattatttt caattacttt tttataccaa
     5821 taaaaactat ctttcttata tcgattatat gtcccctttc cataatcatc agcatccaca
     5881 taaatatatc cataacgttt tgacatttgt ttcgttgatt cactgaccaa atcaatacaa
     5941 ccccatgaag tgtatcccca aagttcaacg ccatcttcga taatcgcatc taacatacat
     6001 ttaaagtgtt cttttaaata attaattcta tattggtcat gaactttttt atcttcagtt
     6061 aaaatatctt tagctcctaa tccattttca actataaata aaggctttct gtatctatca
     6121 tataattcaa tcaaagatat acgtagacct attgaatcaa tttgccaacc ccattcactc
     6181 atttctaaat aaggattttt tacagctaat aacgtattcc caggtgtaat atctaatcca
     6241 gttgtatcag ctgcctcaca agaagacata tagtaagaga atgaaataaa atctactgga
     6301 tactttttca taatttcatc atcatgttct tcttttacta tttgaatgtt attattttta
     6361 aaatacgaca gtaaatatac tggatactca ccaaaaacct gcgtatcact atatgcataa
     6421 atacttctca ttttttgttg agttgccaaa acatcttctg gtctacatgt atatggataa
     6481 tacgttaatt ttgttaacat acaccctact tttgaatttg gaataatctc atggcaaatt
     6541 tttgttgcaa gggcactagc tacaaattga tgatgcatag cttgaaaaat aacttcctca
     6601 aagtttttat ccttaaaacg gtctcgaact aaaccaccag tagtgtacgg atgacgaatc
     6661 atagaatcaa cttcattaaa tgtaagccaa tatttcactt tgtttttata tatttcacag
     6721 atagtttcta catacctaac aaacatattg ataacttgtc gtgaatacca tccatcatag
     6781 tttaaaacga tatttaatgg tggttcataa tgtgacatag taacaagtgg ttcaattcca
     6841 taacttatca actcatcaaa tacatcatca taaaactgta aaccttcttc atttggctct
     6901 ttatcatctc catttggaaa aatacgagac caagcaatac tcattcgata tgtcttaaat
     6961 cccatttctg ccattagagc aatatcttct ttatagtgat gataaaaatc actaccatga
     7021 cgttttggat aatttacttc atcttcagga tgtgctaatc cttcttctat atcttttgtt
     7081 gtgatttcat tattagattt ataatctttc acatctgcat caaagtgtgc ctttgctaca
     7141 tctgatacag accacccttt cccacctaaa ttccaaccac cttcaaattg attagcagct
     7201 gtagctcctc cccaaagaaa tccttctgga aactttctca tatttatatt cctcccttta
     7261 catcaaacaa gatacttcct ttttttacat tgccataaga ctggtttaac actttataag
     7321 cataatctgc tccattattg tttacaatca taacagttga atctaaatta gcatgtgaga
     7381 ttttgtctaa atcaaattga attaataaat ctccttcttt tacattatcg cctgtcttaa
     7441 caaatgtttt aaatccatct ccattcatac ttacagtatt tattccaata tgaatcaaaa
     7501 tctcagcccc attttttgtt cttaaaccaa ttgcatgttt tgtttcaaat aacatcacaa
     7561 cttctgaatc acaaggtgcg tataaatttc cattggtcgg tataattgca actccatctc
     7621 ccaaagtctt acttgcaaat agttcatcat taaccttact taaatctatt acttttcctt
     7681 ctactggagt tactaagata tttacttctt tttcttcttc tagctcttct tcaacaacat
     7741 ctccaattga tgactctact gtatttgtat cttccttcca aataatcagt gtaataataa
     7801 acgagcctaa tattgcaata acaaaaccaa tacttgcaaa aatcaaattg tttccattgt
     7861 ttgggtcaat aaacatactc atactggcaa gccctggtcc aacaattaca aatcctttta
     7921 ctgcaaataa tcctaaaaat gtaccagaaa ttgcacttga gaatacaaca cctaacattg
     7981 ctcttttatg ttgtaaagta ataccatata aagctggctc tgtaattccc atcaaggcag
     8041 aaattcctgc agataatgct gtttgtttta atgtttcatc ttttgttcgc aaggctactg
     8101 caaaacaagc accactttca gaaatattgt gagctaatga agatgtcata tataaagctt
     8161 cataacccaa ctttccaatt gtattaattg aataaggtat tagtgctttg tgcattcctg
     8221 ttgcaaccat aaatggaaga aaagcagcaa gtaatcctac aactaagaat cccattttgt
     8281 tatacaagaa taaaataatg gttgtaaaaa ttgtaccaac gttatatcct aaaggaccta
     8341 aaatagttag agtaattgga acagtaattg ccaaagacat cataggaaca aagaaagttc
     8401 gaattggttt tggtgaatac ttgttaaaaa ttttctccat tgttgccaag aaagacacac
     8461 ataaaatagc tgggaaaacc tgtgcattat aggcaatgtt tggaattgta aatccaaata
     8521 gttcgacacc ttcacttaaa gcagttgttg ttgctggaag caataagtat cctacagcgg
     8581 caatagctac taaacgatta catttcaata cattggcagt agttacagct accataagag
     8641 gtaggaaata gaatgttgca tctgaaatag caactaataa tgtatatata gtagaatctg
     8701 attttaaaat attaaacatt gctaataaca tcaacagtga ttttaaaata ccagctcctg
     8761 caatagcaaa aatcagtggt tgaaaaatat taataataaa ttctataaat cttgttccta
     8821 agtttatttt ttcttcagtt tttacagtac tatcatttgt atctaaaggg caaactttta
     8881 aaatttcatc atacacatca acaacactat ttccaatgac aacttgaaat tgtgccccat
     8941 taactatact cataacacct tgtacttttt ttaaagcatc ctgattgact ttacttctat
     9001 caatcaactt aaagcgtagt ctagttgaac agtgttctaa agctaaaata ttttttgaac
     9061 caccaacttg ttcaataatg tcaatggcag tttttttata attcatcttg taatctcctt
     9121 ctccataatt ttttatgaat ggccattcaa gatgcaaaaa aggcagaacc tatataaaca
     9181 ccttgaaaaa tcaaagcaat atattcgatc ctgcctgcat taccagtaac atgtcttcta
     9241 tttatactat tttgtattat tatattaaca tttgcctaaa agaattgtca atactttttt
     9301 aaattttctg atactaacta atagcacctt tataattcat tttttatgtc aattaaagta
     9361 acagtagcca cccaccaatt agtatcaaaa ttgaacctgg tattttttct tttatatttt
     9421 ctttgaatat aaaatgagca agtattaaag ttattatcat agatacttga gaaaatggct
     9481 ctgctatact aagttctaga ttatttaaag caattaataa tgctaaataa gaatatccat
     9541 taatagcacc acttaaaatt gaaagtccct ttttattagt aaaaatctca caaattattt
     9601 tttgtttctt tttaaatgct aaaaagataa ataaatttaa acctacgaaa aaatacagta
     9661 tagttgaata taatatagga gatacttgta caaaaaaagc cttatccaat actcttccta
     9721 ctgactgcaa aaatatgtat aaaaacatta atctacatgg taaattgtta aaaattacag
     9781 agacattctt taaaaaagag cttacttttt ttaatataaa cactccacca atcataatta
     9841 tgattcctgc aacttttgct aaacttaaac cttcacctaa aaatataact gataaaagca
     9901 gtaaaaacaa tgaatttaaa ctatttattg gagtaacaag tgaaacttcc ccagttgcta
     9961 aagacgttac atacgctact gaaccaattg aatagactaa actacttata taacatggta
    10021 ttaaaaacga ccaatcacta actctatcca ttatgctaaa tggaagtaaa catactcccc
    10081 ctataaagaa aaatagaaat gatgaagcta tatttttata aatatctcct tcttcatcac
    10141 ctaataatct tacaactact ctttcaaaag ctaatagcac tactctaatt aataatgcaa
    10201 aataagataa tatcattttg acctcgctta aaaattaatc cgacttattg ttatattaac
    10261 tgtataaaac taccatatag gtaagtcttt tggatttttt aatattttat gtttaaatac
    10321 aggtacatta agtttttcac ctagtttacg gcattgctct ttataggtac cttttaattt
    10381 atcatgaaaa actatacaat caattcctcc ttcaatacta tttatacact tttctagttt
    10441 ctcaaatcca gattcatcat catacattcc acttacaatc cattgatttg gcaatacatg
    10501 tccaattgat atgttatatt ctttattttt tataatatct gagaaagatt tctcaaaatg
    10561 tacccctcca acacataaca aagtcttcaa aggttcatca caatcaaata ctctaattaa
    10621 tgactttgcc aatacctgta ttgctatact attattaaaa ctatcactac tacttcctat
    10681 ctcaatatcc aacataggta cagaatattc tgtaattaat ttagattctt caccatatgt
    10741 tgttccagac cagtgagttg cttctgttaa tgtagtaaat tcatcaagta gattttcatt
    10801 ttttatatcc tcaatagcat tgattagatt tttaaagtat cttggatttg aatttccaaa
    10861 ttctcctgtt ggaacatctc caattgtatg agctgttagg atatgttctg gagcattttc
    10921 tccctcatgc caatttacaa ctcctgcaaa atcataatct ctgaaatgtc tatttaaaat
    10981 tggaagataa tatttataat tatgacttat tacatctttt gtttttacaa aatgaaataa
    11041 gttattgttt ttatccttaa actctaatac aaaattatca tcaataacaa tatcagtttg
    11101 atttaaatcc attatttctt cacaacactt tatcacatta ctggctactg ggtctttctt
    11161 taaatcactg caaaagaaaa aaactgcttt tttattattc atccataaat cacactccta
    11221 taacttaaat ataatatata ttcataccta aaatcatcta aatatcactc taattccatt
    11281 aaattattta tatataatat actaccatac tcattttagc tatacctttg cctgagtttc
    11341 tatatatatg tgatacatca gctttaaatc ttatagaatt tccactagat acaatgtaat
    11401 cttctccatt tattttaatg gttacttcgc cactaaaaac agttataaac tcttgtgttc
    11461 ctggaagttc agcatttgaa tctaaatttc caccttcttc tatttcaatc ataaatatct
    11521 caaatcttct tttggagtca aatggaaata ttggataact tatatacttt ccattatctt
    11581 caataaaatg gtctatatca cttttttgaa tcaattctat gtcactttcc tgcctctcca
    11641 tcaatgatgt aaatgagatt tttagcccat tagttatttt cttcaaagta gatatagtag
    11701 gatttacctc acacttttca atttgagata gcatactctt acttacacca ctaagttgtg
    11761 caatcttgtc taaactaaga tgtttttctt tccttatctt ttttaaattt tcagcgatta
    11821 tttcatttaa actttgcata aataccccct aatacatact aatataagat aaattatttt
    11881 gattattaaa taaacttagt aatttaatag aaacttttta tccattataa tgtacattat
    11941 gtttaatata cattactttt tttagaatgt aaatagtttt ctgaaatttt gtgaaaatga
    12001 ataaataaaa aactagtaac ctatattttt acaaggttac tagcttttat tataataatc
    12061 tttcatttta actataaaac ttagatgcac ctataagctg tctcttagaa acaatcttag
    12121 ctaggtttgc taatgaagaa atttttatat ctttaaaaga aactaaaaat acaaacttaa
    12181 aatctgtaaa ttcttgattt atattgtata tatcaaaata acatctcaaa ttatcaaata
    12241 agtaattatc ctgtaagtct gcttctatct catcagtagc atcttttaaa tacgctctta
    12301 catcttcaaa taaaacactg aaataagact catctatttc ttcacctaac tcttccaata
    12361 tttcttctat atctaaatca tccatatcaa aagaatttcc tgtcaactgg caatcaaata
    12421 ccaatatatt ttcttgattt atagtatttg atatatcttg tacatattcg aagtctggac
    12481 gtaattctaa aatgtctttt atttcactgc tctttacatg gatttttcct tttctatttt
    12541 caatttttaa atctatcata tgctccccct ttcaatctac aaatctttaa ataccttgtt
    12601 ttataatctt ttcaatatct atccaattac taactctaac tatattttga tgtttaacat
    12661 ctttattata gttagtatcc agaagtatta ctttaacacc atcatcagct agttgcactg
    12721 agtttaaagg attatcttct ataaatatgt cacaactcag ttctcttgcc ttttcaactt
    12781 tataatcact tcctaataag taaacatcta tatctgaaaa tccttgtctt gatagccaat
    12841 ttttagttac atcagttaaa cactcatgtc tagccgttac aaaagataaa ttatgtcctt
    12901 tagataatgt gctaattacc tctgtagcac cctctacaat ctttgcttca tcatatgagt
    12961 gtatatactt attattaaac tccgcataca catctcttat tcccgaacca tacaattctt
    13021 cccaattatg tgttatacac tctgcttcag ttatattttt attaaagata tcatttaggt
    13081 atggaagaaa atgataaggg cttgttattg ttccatctat atcaatacat atattcaatt
    13141 tgttcatttt tacctccatg taacatttat tgatttgatt aatcaaatat tatagcacag
    13201 ctttaattat aaatcaaaac tctggatatg actataccta tataatacca aaaagcttgc
    13261 atatttaagc aagcttttcg taaattttac atttttaact aatatataag tttttctaag
    13321 gttggttcca ctccaaattg tgatttcagt tctttatatt cttttaatgc tttgtcatta
    13381 ttcgttttag tttttatcgc tcttatcatt aaattttttg gtgtatcaag tggagatatg
    13441 tattctacta cagaagtatc atatccattg ccctccaata acaatgttct taaaccatca
    13501 gttattaaat ctgcaaatct agctttaaat acaccatgtt ttaatattgg ttccatagct
    13561 tcatatctat attgccctaa taactcctta tgacaacatg gtactactac tatagcttca
    13621 gattttgctc taattcctag acctattgcc atatctgtag ctgtatcaca agcatgtaga
    13681 cttattacaa ggtcaacatc cctattaggt gtataattag tcaaatcctc ttttataaat
    13741 gacatatttt tataacccaa gtttttagcc atattttttg atgcttctat aactacatct
    13801 gaataatcta ttcctataaa ataacagttt ttcttcaata cttcttttat ataaaaattt
    13861 aagacaaagc ttaagtaaga ttttccacaa gcacaatcca agatagttat acagtcttta
    13921 tcctttattt cttttaaaat actatctatc aattcaacaa aatggtctat ctgattgtat
    13981 tttcttattt tatcattttt tatcttacca tcttttgtaa gtactccaat ttcttttaaa
    14041 agtgcatttg cttgtcctac ttttacataa taatctctgt tttttatttg agatgccgta
    14101 aattcatcta ttttaggtac ttcttcctta ttgtctaaat attttacatt taccttctta
    14161 ttgtctcctt caattacaac aatagttcct cgctcaacat atttaaatac taatccatca
    14221 taattttctg cctctttaga aatattctta agcaactcat taaacgtata taaatctgat
    14281 tttcctttaa aattaaattt atatttatta tcttcctcta ttgcaattcc tttaaactct
    14341 tttcttccag atttaaaaat cacctctaac tcaataaaaa aatccctatt atcaaggttt
    14401 ctttgagtaa tccccataaa aaacatattt agttttccta tactctgttt attcatcata
    14461 atctcccttt taacttatat ccttaaatct tattaattaa tattatttgt ttctgaatta
    14521 tttatttctt cttttaaatc gttcaatcta tttttaaaac tttctatctg cttatctgat
    14581 aaatcaagat attctgttat cttccctata tatttagggc ttttagtatt tattaatttc
    14641 aaagcacttt ccatagattt ttctctaagc tcatatgctt tctttacgtc atctctagca
    14701 ttactcaatg tttctgtata cttctcctta gaaagttctg gaatctgcat attttcatat
    14761 tcttttacaa cttctttaca cttgtttctg gcatttgtaa catctttttt tatactagat
    14821 aatttagtta tattttttgc tatatcctta gtgtaaggta tacattctct cattggaact
    14881 aaagctgctc tttctatatt ataaatttct ttcttaaaaa ttcctatact ttccatatct
    14941 atttttttta tatcttcact atttttttct ttacttgtat atttattatt ttcttttgta
    15001 ttatcttctt gtttttctga tttattattc actgaaacat tactatcaga attattcttt
    15061 tcttttatat cattacttcc ttcttcatta ctttctttat tttgtatatt tctatcttgt
    15121 ttgttgttta aatttttatt atttgatatt tcttcattct ttttattatc ctgttttaaa
    15181 tcagtacttt ctttttcctt aaaatttgat acatactttt catcatatgt ctcatcagaa
    15241 atataattgt gataatacat agactctttt attttattaa gtccactcat ataaatatta
    15301 cttatcatta ttgttgtagc taataccaca taaatactac tgtagataca agacctctta
    15361 aaattcttgt aatttctgaa tatcactact aaaggaataa gatataaaaa tataaaaact
    15421 aatatccacc tcataagtcg tgtctccttt ctcaaaaccg aaatccctca aatatttatt
    15481 tttaatcatg tatcttatag tatttaccaa tttatgtttt ttaatcgtga acttttatta
    15541 aattaaattc tgtatagtca caagatgcta atgtatattc tactccattt cgaatcccct
    15601 tcaatcccat tttaaaagat tctttaccat gcaagtgacc ataaatcacc ttttcaacat
    15661 tatattcttc aaataacttt gtaaataaag attcttccaa tttatcattc gtaggaggat
    15721 aatgagtaat cacaattatt tttgagtgac cacttttacg agcagattct aatgatagtc
    15781 taagtctatg ttcttctctt ttataaactt tttcatcagt ctcatcaaat ttaacatcat
    15841 taggacatat ccagccccta cctccacaaa ttgcataatc tttatattca taaaaatttg
    15901 tctgaataaa acgcatgtct tcatatagct tatttaaact tgtaacggtt gtccaccagt
    15961 aatcatgatt tccctttata agtattttct gacctggaag tttgcttatt atatctaaat
    16021 cttttttagc ttcggataaa ttaattcccc aagatgtatc tcctagtact aagaccatat
    16081 cttcttcctc aacaacttct ttccaattat ctataatttt cttttcatga ccatcccaat
    16141 tacttccaaa gatattcatt ggcttattga ctgatgttga aaaatgtaaa tcacctatag
    16201 catacaaact cataatatca ttcctttctt aattacacta aataggctgt ctctttttag
    16261 aaattatttt ccattaagag gcagccccat taatatttag caaattttct acaagtagtt
    16321 tttactgaac tactttatca tctaccttag tatccttata ttgctctaat aatatatcta
    16381 tttcttgttt taattccaaa atttcagtta tatttttatc tgtttcagtt ctatcaagtt
    16441 ttctttggta ctgcatagct ttatgtgtat cacccaagtc atataactct tgtattctat
    16501 ttagagtatc tctaatagct atagacttca tttggtacat agcctgagct ttcattatgt
    16561 cctctcttat ttcactcatt tcttggtcta aaagaaaggc agcatcagat gctcttctaa
    16621 gcctttcagc aagagtctca ggtatgtaat ggtcatattt atattttaat gaatgttcta
    16681 ttgtagccca gaaattcatt gcaagagttc ttatttgtat ttcacatata atttcctttg
    16741 aacccgcaat ggagtttata gggtatttta ttataacatg atagcttcta taaccactat
    16801 ctttgtaatt tgtaatataa tctttttctc ctattatagt catatcattt cttactttta
    16861 tcaaatcaac tatagcatat atatcctcaa caaactggca cattattctt ataccagcaa
    16921 tatcatcaat ttcagtttct atatcttttg catttatcct ttttaactta gatattatgg
    16981 aagatatttt ttttgttcta cctgtgacaa actctatggg agaatattca ccttttgcta
    17041 aatattcttt tcttatattt ttaaatttta ttttcaattc ctctactgca tgttcataag
    17101 gtgctagtat ctcattccat ttttcgtatt ccatattgct caccctttat ttgtttttta
    17161 tgaccttctt tattttatca taatttattt tgtttttgta tagtaaagca attctccatt
    17221 ttccaatata taccctattt cttctaaatc aactaagtaa cttatgacag atactaacga
    17281 agatttaaaa aaatgatact ctttataatt attgcttaaa ttattgttat ttataatgtt
    17341 ttttaataaa atttctaaag atttcggttc tacaagcaac tctcttattt gatataaata
    17401 tttttttaaa gcattcaaat gtttttctat taatttataa gaatcttctt tcgatataac
    17461 ttgcttgcca tgccctaaaa ctaagtactc aaaatctata ttttttaatt tttctaatga
    17521 atttatttgt tcttgtatat catatagaaa caagaaatcg tattttgata aaatttcatc
    17581 tcctatcaat aaatcgccaa caaaaatcac attatccttc gtcaaaacag ctatactacc
    17641 aggtgtatga ccctgaaatt caattatatc aaatatttca ttgtttaatt caatttttcc
    17701 agcttctata gatttatcta tttttatatc atccaacatt ttatttttta agatattatc
    17761 cataaataca ttgctctttc ccccaacaat atactttgaa aacaattctg gattttctat
    17821 atataattta tcgtattcag atgacattat acacacatct ttataatatt ctttaaattg
    17881 attacaagct ccatagtggt catcatgacc atgagtattt ataatatatc taacctgtat
    17941 attattttca tctaatactt tatttactct cctaggtctt gaaccacata accctgggtc
    18001 tatcataagt gctgtgttat cttcaaatac atatattcct gtattcgtgc caccttttat
    18061 aaaaaaggta tttcctttta cttttgtaag attcaccttc ttcacctcat tttgacaata
    18121 tttatgatac aatttattac ttactaatat aaaactatac aagaacaatc ctttttattc
    18181 tatctatagt tctttttctt attttgtatt ctttagatat ccttattttc acattatatg
    18241 ctaaatttct ataaagtaat gactctataa aatattcaac tatacctcta tccctaaagt
    18301 ctatatctat atttccactt gaataaatat ttgagtctaa tatcataagc tcatcaaaaa
    18361 agcttaatct cttagattta cttaaataat ctttatttgg aataaatcta tcacaataat
    18421 ctatcctgta atttactact tcatcattta tttcaaatcc atattgcttt ttcattaact
    18481 ctctatagtt attatttttc tcaataacat tatctaaatt tttattataa tcctcttttt
    18541 tccaatgtcc aaacatccta caatttaatg gtctaacttc atatattaaa catctattat
    18601 tagtatcttt aaatggacat gggttctttc ttgtatactc ctcaaaataa taatctaata
    18661 ttttacttat acagcttttt tttaaatcaa ctctatcttc aagataacaa aatatattca
    18721 aaaactcaat taaatttata cctactgact ccatacaaca atttccacat ccagaacaat
    18781 ttcctactgg caaggactta tatacatcat ttagtttgtc aaagagctta tttttaatgg
    18841 aataatctat acaatttaaa atatctttat tttttatact agtcattatt attactcctt
    18901 gttataatta ttaagttaat acaaacaatt attataacat attttttaaa tttaatcgca
    18961 tatggaggta ttttatgaat agatatacaa aaataattaa tatgatggga agttattaca
    19021 caaaagactt tgaaaaagaa aaaaagaatg taataaaagt tagagaagtt aaagaagata
    19081 cagttagaaa atttttctta caaggtgact gtgaagttct tgtagtattt gaagacactg
    19141 ggaaagaaat acttattgat gacttttctc ctgaagaaga tatcaaaaaa tatttaggag
    19201 caaaatttat aaataaaaaa agatagttat caaaaataat tctaaaatta aaatttaata
    19261 aatgtacagt tataattcta tataattata gttaaaagtt atcttttatt gcttttttag
    19321 actttaagat agcttttttt ctattttttg taaaataatt ccataattca cattaataat
    19381 tcacaaaatg atataatata acaaatagat aaattttaaa tttctaaata cataattaat
    19441 attttgagag gtgattttat gcaaatttat tttagagtta aggctgttgg caaacgcaaa
    19501 cctatgctag aacttacccc ttttgatgta tctgacaaca tcaattgcct aaaagaagct
    19561 atctctgaaa ttgtatctaa aaatgttctt gaatataatg agaaaatccc agaaaaatca
    19621 ataataaact tcttaactaa tgaagaaatt gaatctcaag ctgatattgg aaaagttgga
    19681 tttggctcta tttacaatga gaataaacaa tctgtagaaa aggcaataga agtagcgtta
    19741 caggcatttg aagatggaat ctacaaagtg cttataaatg aagatgttat tgaaaaactc
    19801 gattcctcta taaatctgaa aagtggagat atatttactt ttataagact taccttgctt
    19861 gctggaagaa tgttttaaaa taaataattt ggaggtacat aaatgttaga acgtactaga
    19921 gtagaaaaaa atcctaaaat aattgaaaat tttaaaaata attttactaa atcttcttca
    19981 aaacagtact acgacttagc aaagtctctt tgggattgca tagaaaatag ttcatactat
    20041 tatagagaac ctgaagacaa attcttaaat atgataaaga aatactacaa ttgccactac
    20101 tacgaaatta aaaatatgga cgagctcctt tctggacctt taaaaaatgc attagaatta
    20161 atatttactt ctgaacaagt agaagaactt tgccaattaa ttaaaagaaa gatggattat
    20221 acatattcag gaggatatta tcgtaaaggt tatcgctcaa ataaacttgt ggattatttt
    20281 agaggtatta taaggtttat ttcaaactat gttgatttaa tttattatga tttttcagtt
    20341 atagattatc ttactcttcc aaataaggtc ttgtactatg actctataat gagtgataaa
    20401 atagcactag aaatagacaa aggaaatcaa aaagtaataa gtgctttaga agaagtaata
    20461 tttggagaaa atcaaactgc tctacttaca agacaaatga taattggtat catgaagagt
    20521 catagtgata aatgctatga aatgctttct aaactccttt tggcagccaa acaacaagaa
    20581 ggacttagac agcaaattgt agagagttta gatgagggta caatttctgc atcaatatac
    20641 atgttaaaaa ctattttgga caacaattta gagcgattta gttctgttat aagagccttg
    20701 gatacatgga caggacttgg tttttcagac caaaaacctg gaataatacg taaatgttta
    20761 gaactttcat ataaatcatt gactgatgaa aagttccgta tagaatcaat taatagcaat
    20821 gataatcttg aaatttattt tgccttgtgg gctactgcaa cttacaacat atatgactct
    20881 tactctctta ttgaaaactt actttcttgt caggaaaaat ataaaaaact tgtagctctt
    20941 tactttttat cgcatacaga aagtacatat tttaaacatt ctatagcatc taaaaacatt
    21001 aagggtgatg atttagagat actagcatgg gtaattacaa atttctatgt agaaggttct
    21061 gttggctact actatagttg gcaaaacaga gaaactaatt ttgacttgtc aaacactcct
    21121 attgacaaag actttgatgc tagaaaagaa caatttgaaa gtttaaaaca tactttagaa
    21181 attttaaatt caaagacaaa atcattttca ggaagtgtat ttccatggac ttggattgaa
    21241 atttcttctc atgaaatact taaatgtatg atgactttaa cagcatacga tatgaatgct
    21301 caatttatag atgtgcttat ggaaaattgt catcttatga gttcagattt aagagcttca
    21361 cttatagtca attttgtaaa tgaaccaaag acagatagac aacgtgaatt tttattggaa
    21421 tgtttaagtg ataagagtgt ttccaataga gaaacggtat tgagtctact tagaaagctt
    21481 gagctaacag atgtagaatt agataagata accaatctat tgtctttaaa gacaagctct
    21541 attagacaaa cagtaataaa aattttactt gaacaagatg attcaaactt ggaaaatatt
    21601 gcttcttcac tgataaaatc ttcaaattct caaaaatgcc ttggaggtct tgaaattgta
    21661 aacttattaa aagacaatac tgctagacaa gaactatata ataagcttgt tttacttata
    21721 gaagatattg ataaatctaa aaagaataca tctcaagttc aaatactaat tgataatttg
    21781 ttaggtaaag caaaaaatga ttactgcaaa gaaaatggtt ttggaatata taaccatgaa
    21841 aacaaagttc aaattccaga acaatttgat tttaaagatg attctaatag ctcatcaaag
    21901 cttaataaaa ttatttcaaa tataagttta tctactcgtg aggattctgt ttctgtagca
    21961 acaaaaaaag aagcaaaaaa aattctcgat acggatataa ataaaataat aaaagtttat
    22021 gaaaaatttg atgagcttat tactgaaaat gcagattatg aatatgaagt tgaaagatgg
    22081 tcaggtaatg tagacaaagt acttttaggt tattctactt ataacttgac tcctattaaa
    22141 tataaagttt ctaatgatac tcttgataat tatccattag cagaactttg gagagaaact
    22201 agtaaaaaac ttgacttaga ttacaaatta atacttgata tcttatttta tagtataagt
    22261 acatgtggat ataatgaaac agaaaaaagt tggttttcat ctatatattc aaatgtcctt
    22321 gactctaaaa aacaaaataa aatatataca aaacttgaaa aacttaaatt taatggactt
    22381 acaagaaaac ttttaagagt tttactaaat gagtttgacc ataaagaaat atttaactat
    22441 tgtttagaaa tatactataa acttagaaac ttattgacta tagaacaatg taaaaaacaa
    22501 agagttgaat ttactaaaaa ctattacaga caaaatgaat actgccctgc tttaaatgcc
    22561 cctattttaa actactggct tgataaagca cattcgttta tttatgatga tatttctttt
    22621 actaagtttt tctacactac gttttcaaat tatcagttgc tagaatataa gtttcctttc
    22681 tatactagca taaatgtgtt tgctcgtgca catgaattag gattaatgac tgaagagcaa
    22741 gttaatagag aaatgataag tggatacaac gcatcaaata taataagaac attgacaaat
    22801 cctagatggg ctggcgacac attagaaaag tacccttggc ttaaagataa tttaaaaact
    22861 gttacaaacc gaattataga aattgaatca cgtagaggtg atatgccaac agaagtgtct
    22921 catctagcta ataatataca atactttgaa ggtataaatt attttgtaaa tattttggtc
    22981 gctcttggta aagaaacttt ccagagagga tattcatatg gtagcaatta ttcaaaaaaa
    23041 gatgttttaa gttctctact taaaaattgc tatcctacta aagaagatga ttcaaaaaaa
    23101 ttaaaaagtt tacttaaaaa taccgacatt actgagttaa gattgataga atctgctatg
    23161 tatgcccctc aatgggtaaa cataattgaa aaatatttaa actggaaggg tctgaaaagt
    23221 acaatttggt acttccatgc acatataaat gaaggcttct ctgcacaaaa agaatcagag
    23281 gttgctctat tctcccctat ttcaccacgt agtttcattg atggtgcatt tgatgtagat
    23341 tggtttttag attcatataa aactattggg gaagaaagat tcaatatact ttacaagtca
    23401 gctaaatata taactagtgg tggtaactct catagacgtg cacaactcta tgctgatgct
    23461 acacttggta agcttgataa agacatgttg atgaaagaaa ttgaaacaaa tagaaatcaa
    23521 gataaattga gaagtttctc tttacttcct atgaaaaaag gagacctaaa agaagcaact
    23581 ttccgttatg aatttattca aaagtttgct aaagaaagca agcaatttgg tgcacaacgt
    23641 cgtgaaagtg aatcaaaagc ttgtactata gcgctagaaa atctagctag aagtgctgga
    23701 tttggagatg taaatcgtat gatgtgggct cttgagactg aaaaactaaa tgaagttgct
    23761 catctattta aaccaaaaga tattgatggt acttcaattt ggatagatgt tgatgaaaac
    23821 ggaaaagcat ctactaaagt tcaaaaaggc aacaagtctt taaagagtat accaaaagct
    23881 attgctaaac atccatatgt acttgaactt aaatctgtcc aaaaagattt aaagagtcag
    23941 tattctcgtg caaaacagag tttagaacaa gctatgaaaa atgaaatagt atttacagtt
    24001 aaagaaattg ccaatatcta taaaaatcca gttatctgcc ctttgattaa aaatctagta
    24061 tgggtatgtg atgataatat tggatatgtt tataatgata agtctaagtt ctttatttgc
    24121 aatatagaag gtgaaactta taagttgacg gcaaaaaata aattaaaact tgcacatcca
    24181 gttcatttgt ttgaatctgg taagtggagt gagttccaac atgatttatt tagtaagcaa
    24241 attgttcaac catttaagca agtattccgt gagtattata gaataaacag tgatgaatta
    24301 tctgaaaaaa ctatatctcg cagatatgct ggtcaccaaa ttcagccaaa gaaaactgta
    24361 gcacttctta gaaatcagct ttggactgtc gattatgaag agggattaca gaaagtattt
    24421 tataaagaaa atatagtggc aaagatgttt gcacttgcag attggttttc accagcagat
    24481 atagagcctc ctactattga aacagtagaa ttttttgata gaaaaactta taaaagttta
    24541 gaattagctt ctatacctcc aattctattc tcagaagtta tgcgtgatat agaccttgtt
    24601 gtaagtgtcg ctcatgctgg tggtgttgac cctgaaacta gccattctac tgtagagatg
    24661 cgtatagcaa ttgctaaaga acttttatta ttattaaaaa ttaacaatgt caattttgaa
    24721 ggctctcatg ctcttatagc aggtaattta ggtgagtatt ctgtgcatat gggttctggt
    24781 attgtacata aaaaagggat gggtgctttg aatatacttc ctatacattc tcaaagtaga
    24841 ggtaagatat tccttccatt cgctgatgaa gaccctaaaa ctgctgagat tatgtctaag
    24901 atactattac ttgctgaaga tagtaagatt aaagacccta gtatcttaag taatttataa
    24961 gtataaaaac tatctctaaa atatattgga ctttcttaaa aaaattagaa agtccaatat
    25021 atactatact gtaatttata tagattaaat cataattaca aataattttt atataaactt
    25081 ctcttataca ttatctttac ggtacttatt atatcacaca aaaagtattt ttcttctatc
    25141 ttcactagaa tcttttaacc ctataaaatc tatataaaaa atctttttct agagatttgt
    25201 ttaatatggc attttcttga aaatttataa accttatctc taatgaagat ttatttatag
    25261 gtataacctt atgtataaat cttagattta ctatgtattg tctatgggtc ataaagaaat
    25321 taggaggtag gcgttttttt aaatcatcaa agttctcata aaactttatt atatcttcat
    25381 ctttagtgtg tagattaatt gctcttgaat ttttctcaaa cataactata tcatcaaaat
    25441 taatcatatg tatctgcttc cttattttat atacaaaaag ggtgtcttct ataaaattat
    25501 tattagcaat cttatgggag ttaatatggt ctattgctat gttaattgaa tcaagtattt
    25561 tttctttttt aaatggttta actacaaaat ctataggatg cactttaaag ctttcaagac
    25621 tataatcagc gaaacccgtc acaaatacta tatgtatatc cttatctata gaaagaattt
    25681 cttcagcaga atcaatccca tttttatatg gcatatcaat gtcaataatc aataaatcta
    25741 ttttctcatt ttttataaat tcaattgcct ctataccatc cttaactttt ttaacataat
    25801 ctacatatcc agactcttta gctatatttg ctatatcatc tcttacaatc ttatcatcat
    25861 cacaaatcaa aacttttatc atagactttt ctcctcctaa ctaataatat tttgggatta
    25921 agattacaaa ttcagttaaa aaatcatcac tatttacaag tatactataa tcatacttat
    25981 ctaatatatt tttaactaaa tgtagcccat atcccctatc ttgtccttct ttagtactaa
    26041 atccattcca aaatatactt tcaacattat gtattttagg accattattt tttatagcta
    26101 taatatactg aaattcatct tcatatgcat gtaatcttat atacttcttt tcttttttta
    26161 tagtagacaa agactctatt gcattatcta ttatgtttaa tagtactgaa ctcatatcat
    26221 taggttcaat ctctaaatta tccataaaat cttgaatgta gacatcaaaa gatatatcct
    26281 tttcaagaca ttcctcgtat tttaatgaag ctatagcatc taaataagat acttttccat
    26341 accttgaatt ttttgattta aagctatttg atatattcat tatatattct ttggcatctt
    26401 catctagccc agtatttaat agagaataca ctacttgcaa atgtttcaaa tagtcatgtt
    26461 tttgacttct taatttgata attatattat ccttatgatt tattttacta tctagttttt
    26521 gtaatttata ttcctgttca ttattattat ttatcaatct tataacttta aagcctgtat
    26581 aaaaacttaa aataattaaa accaaaaaaa gtataatatt taatactcct tcaagtaaaa
    26641 aactatatcc taaccttaat tgtatatatt tagtgccctc cataaataaa atcaatgcaa
    26701 aacacgatat aaaaaatgtt aatatgcctc tttttaatat gtctaattct ttgtaaaatt
    26761 tatacttatt cattataaga ttgctaaata taaacaaagt tagtattact ataggaaata
    26821 caaaattgtt atccatgatt cccctcccct ctacaattta tatagggatt atatcatttt
    26881 aaaaaaatta tgtaaaaagt taaaatttac atatatatta attaaacttg taaaaataca
    26941 gatgaatttg tacaattaac tacttaaaac ttgaaaatac ttactttgct atatatttta
    27001 gataaatata taattgattt agttaagaaa ggaagtggta aatatgaaag ataatttgaa
    27061 aatagtacta aggtatataa aaagttataa agctaggtct ttagcaattg ttgtgagtat
    27121 aattcttgct acatcactcg ttgttggtat tggtaccctc tcaagaagtg ctcagcaagc
    27181 agatgtagat agattgaaaa gagagcttgg aactgaccat gtatacttta aaaatataaa
    27241 gaaaaatcaa ttaaagtcca taaaatctag caaagatatt aaaaatctgg gtataacatc
    27301 ttactatgca tctacagatg ttaatgaaaa attacctata aacatactat atgcaaataa
    27361 aaattatttg actagtcatt ctaaacttat aaaaggtcga tttccaaaag ctagcaatga
    27421 ggtggtagtc gagaaatgga ttttaaatag tatgggctta aaaccagaga taaatcaaaa
    27481 ccttactttt aaattatatc aaaaagaaaa tccagaaact tttaaagttg ttggaatcct
    27541 tgaagataga tttatagaga aaaaaagggg acaatgtgaa attttttcta atctcaatga
    27601 atcagaactg aataatttta caacttatat tgaatttaat gaaggcagtg atataaatac
    27661 aaacatagac aatataataa aaaatgctat gttagatgag aaaagtatag gaagaaactc
    27721 aatgcttata gaatctacta tgaaaaacgg tactttagat aattcaagta aatacattgc
    27781 aattgctatg agtctatttg ctggtattgt aatatatagt atctatgtta tatcaatata
    27841 ccaaagagta caggaatatg gcatcttaag agctattggt tccaccaact ttaggatttt
    27901 caaacttatg ctttatgaac ttttcatact tgctctaata gcaatgccta taggtatatg
    27961 tataggtatg ggaggtgcac aaatatttaa taggtctgta ggaaatattc aatttgaagg
    28021 aaatataaat gttacacctt ttgttattcc agataaaata attctcttat caattgcatg
    28081 tacaatacta ataatgctaa ttataagttt ctttacatac ttaaaaataa gaagaatttc
    28141 tcctattgat gctatcagaa aaacttttgg atctgataaa aatgtaacca aagttaatta
    28201 tttaatatca aaattaactt taaatatgtc agtaacaaaa tctatatctg cgaaaaatat
    28261 ctttagaaat aaaaaggggt tcatgataat tgtattatct atgagtatag gaggtataat
    28321 cgtcataaaa gacaattata aatattcttt tttagatgtg caaaacaaat ccgtacaaga
    28381 acaaacatat atgaatgcag attttattct atcaaatgtt tatctcaatg aaactggtaa
    28441 caatacttct tttaaagata taaaagggtt tagtgatagt cagatagata aaataaaaaa
    28501 tatagatgga attgacaaag tcaaaactgc tagtatctta aacacaagaa tagaggtaaa
    28561 taaaataaat agattagatt actacgaagc tataaattca actccttatt ataagctaaa
    28621 tcctctgttc ataaaaaata agactactgg caaatataca ctaaagcaaa agctaaaagg
    28681 ttataatgat gagatgataa agtcattaga aaaatactta gtaagtggaa atataaactt
    28741 gaaaaaaatg aaaaaagaaa atttagctat tgtatatgta ccagaaattt ctaaaacaca
    28801 gaaatacaca aagactttta ctcctggtga agggacacca gctgtagata taaaagtagg
    28861 tgatactata aaagtcaaat atccaaatgg tgggatggat acagggcttt atgaaagtct
    28921 aaaagataat tatgaatact tagaatatga atttaaagtt ggagctatta taagttatcc
    28981 ttttgcagat aatggtatgt actctggaga tgatagtgta gatgtaataa cgagtagcga
    29041 atacctaaaa aaattaactg gtgtagataa gtataactta gtttatgcag accttaatga
    29101 aaatgcaaac aagaaaaaaa taaataacct tttaggtaaa attggaagtg aagttcctgg
    29161 aactacaaca gtagatatga tggtggaaaa agaaaattct gataagatga catctagaac
    29221 tatgatttat agttatggca tagtagcaat aatgttcata atcagtgtac ttaacataat
    29281 aaacaacata agttataact taacttcaag aactagtgaa tttggaatgt taagagctat
    29341 tggtatctct gagagaggat ttaaaaatat gatactttat gaaggaatat tatatggtgt
    29401 actctcaagt ataattacta tcgtgtcagg acttataata caatttaaaa tgtattatat
    29461 gcagggcttt gtatcatatg gattgggatt ttcaatagat tacaaaatat atatactagt
    29521 tgttgtagca aatataattg taggtattct agctacatat attccatcaa gaaagataaa
    29581 taaaattagt atagttgaag ctataaacat tacagaatag gaggaataat tatgcctata
    29641 ttggaaacta ttaacttagg taagatttat ggaaaaaagg aaacatctgt acatgcacta
    29701 aagaatgcaa atttaaaaat aaataaaggt gaatttgttg caataattgg gccaagtgga
    29761 agtgggaaaa gtacatttct acatttagta ggtggtcttg agagaccaag taatggtact
    29821 ataaaagttg ctggtaaaga tatatgttgc ctttcagata aagaactagc aagatataga
    29881 agacaaaaag taggatttgt ctttcaacag tataacttaa ttcctgtatt aaatgtaaag
    29941 gaaaatatag aattaccact aaagttagac aataaaaaaa tagataaaga atatattgaa
    30001 gaccttataa atttattggg gcttaaggaa aggaaaaatc atcttcccaa ccaattatct
    30061 ggtggtcaac agcaaagagt tgctattgca cgtgctttat ctgcaaaacc aagtataatc
    30121 ctagcagatg aaccaacagg aaatttagac agtaaaacta cagaagaagt catggattta
    30181 ctaaaaagtt ctataaaaaa atataaccaa acccttataa taataacaca taatgaaaat
    30241 attgctagaa aagcagatag aattatatct ataatagatg gagagcttaa attaacactc
    30301 taaaactatt tatagaaaag aggatttaaa tgttattgat tttaggtaat ttaaatttaa
    30361 acttggattt tgactacaga ataataagag aagaaaatga tgatgtagat atatttatag
    30421 atattaatta tcgtagctta gatatagata ctgatggttc taacttattt aattctagaa
    30481 tacaatttcc atttgtaaga gcattgattc taaggctaaa taagaacaat caatgtatga
    30541 caattcattt gttaagagat atagatttat tctctgcttt tgccaacttt gaagtggatt
    30601 atactgactc tatagtaaat ataaaaaatc aaaatgagaa agtaatttta aataaatcta
    30661 tcaaaaaata gtaagggggc cttaataggc cccaattttt ttcttttcta aacttattat
    30721 atcatgataa ataaattagt caatagaatt ttctgaatat ttttataatt ttttcataaa
    30781 gttttttata tattatgctt taaaattata tgtaataaaa aaattttccg actaatttta
    30841 aagttaattg attaaataca catattcaaa attatcttta aattactgac cttttatcat
    30901 ttccattcag aatttaagtt ataatctatt atttataact atttatacat atctctaata
    30961 aaactctatt tatattcaaa tctaataatt tatatacaaa cccaatagaa cctatgttgc
    31021 acaatagata ttatttacca taataaactt ttagatatat ctcttttaat tcactcatca
    31081 atgggtatct aggattagca cctgtacatt ggtcatcaaa agcttgttca accatagcat
    31141 ccaatctttc taagaattta gattcttcta ctccagcctc ttttatagtc ttaggaagac
    31201 ctacttttgc ctttagttca tctattgctt ttataagatt atctactttt tcttggtctg
    31261 tacttccttt aatacctgca aaagaagcaa attcagcata tctttgtatg caatcaggat
    31321 atctgtattg tgagaatgca cccattttat ttggagcttc tgcacaattg aacttgatta
    31381 cttcatttat taataatgca tttgcaacac cgtgttgaac atggtggaat gcacctaatt
    31441 tatgtgctaa agagtgacat attcctaaga aggcatttgc aaaagacatt cctgccatag
    31501 tagatgccat tgccattttt tctcttgctt ctttatcatt ctttccattt ttatatgcac
    31561 gaggtaaata ttcaaatatt attttacctg cttgtagtgc tagaccgtca gctggttcag
    31621 ttcttaacat agatacatat gcttctaatg catgtgttaa agcatcaaca cctgatgctg
    31681 ctgttaatct tggtggcatc tccatcatca tatcagcatc aattatagcc atgtttggca
    31741 ttaattcata atctgctaat gggtatttta cacctgaatc ttggtcagtt ataactgcaa
    31801 atggagttac ttctgaacca gttcctgctg aagttgggat agcagcaaaa tacgcttttt
    31861 cacccatctt agggaataca tatactcttt ttcttatatc cataaatctc atagctaagt
    31921 cttggaaatc tacttctgga tgctcataca ttacccacat tatcttacca gcatccattg
    31981 cacttcctcc acctacagct attattaaat ctggttggaa atcagccata gctttagctc
    32041 cttctcttgc acaagctaat gttgggtctg gagctacatc aaagaatgta gtatgcttaa
    32101 ttcccatctc atctaataaa tcagttaatt tcttagtata tccattatta tataggaaag
    32161 aatctgttac tataaatgct ttctttttat ccataacatc cttaaattct cttgctgcta
    32221 cacctaaaca tccttttttg aaataaacct tttctggtgc tctgaaccaa agcatattct
    32281 ctctcctttc agctactgtc ttgatattaa gcaaatgttt tactccaacg ttttcagata
    32341 ctgagtttcc accccaagaa ccacaaccaa gagtaagaga cggtgccaat ttaaagttat
    32401 ataaatcacc tataccacct tgtgatgatg gagtattaac taatactcta caagtcttca
    32461 tagcatttac aaacttttct actctctctg gatgatttat agagtctgca tataatgaag
    32521 atgtatgacc atagcctcca tctgcaacta atttttctgc tttagcaact gcatcttcaa
    32581 aacttttaga cttgtacatt gcaagtacag gagaaagttt ttcatgtgca aaaggttcat
    32641 ttaattcaac agattctact tcaccaatta ttattctagc tgtttttgga acttctacat
    32701 ccgccatttt ggctattaca tgtgctggtt gtccaactat tctggcattt aatgaaccat
    32761 caattattac tacttttcct actttttcag tttcttcttt atttaggaaa tgtgctccac
    32821 gatatttaaa ttctttttta acttcttcat atattttttc tggtactatt acagcttgct
    32881 cggaagcaca tatcatacca ttatcgaatg attttgatac taagattgaa cttacagcca
    32941 tttttatatc tgcactctca tctattattg caggtacatt tccaggccca actccgacag
    33001 ctggtttacc tgaagagtat gcagatttaa ccattccagg tccaccagta gctaatataa
    33061 ggtctgcctc tgccatgaca acattagtta attcaatcga aggaacatct acccaaccta
    33121 taagtccttt tggtgctcct gccttaactg ctgcatcatg tacaactcta gctgcttcta
    33181 tagtacagtt tttagctctt ggatgaggag agaaaattat accatttcta gtttttagtg
    33241 ctattaggga tttgaatatt gcagttgatg taggattagt tgttggtata actgctgata
    33301 aaacacctac tggctcagca attcttgtaa aaccaaatgc ttcatctttt tctatgacac
    33361 cacaagtttt agtatcttta taagcattat agatatattc tgaggcaaaa tggtttttta
    33421 taaccttatc ttcaacaata cccataccag tctcttccac tgccattttt gctagaggta
    33481 ttctttgttg attagctgca gttgaagcag ctaagaaaat cttatctacc tgttcttgcg
    33541 taaatgttgc aaattctttt tgtgccaatc taatttcttc taatctcatt cttaatgttt
    33601 caacactgtt gacaatttca ggactacata cttcaacatt tgatttttct actacctttt
    33661 cttttttctc catactaaaa acctccctaa aataattatg catctctaat ttttataaat
    33721 cttaaatgca tcatctatat ttttaactta tacttaaaat aattttatag atttcatctc
    33781 tataccttag attttattta ttttactctc ttaggtcaag aagttttttt ctgaatattt
    33841 tgtcaattta ttttttaaca aatatattat tttttttact tttactaaaa ttttttatct
    33901 aaatgagata tatttcattt gaataattta cttcgactaa ataaaatact aaaatgataa
    33961 tttatatctt tcattttttt tacttattaa attttatatg ttatttgcat gttatttgta
    34021 taagtagtaa ataaaatttt tgtcgtattt ttataaaata acacttattt ttgacttgta
    34081 tgcaattttt ctttttataa caactgtata gttttaaaaa atatataaac taaaattatt
    34141 ctaatctcta taagttattt ttaagtcaat atgtaataat tatgcttttc atatagataa
    34201 ataattttta tattaagacc gttaattttt taatgataat atatatacaa aattttttac
    34261 agtataaaat atttataaat ttttagttta ttgacgtatt aattaatttt ttcccaggta
    34321 gatttaatca atttattttg aataaaagta aatttaattc gatatttgat tgggtaaaag
    34381 tatatataat aataattttt atattaaatt tgtagtattt atgtaagaaa taaattttat
    34441 ataatatttt ttcactaaat ttttttcttt ttacaacaaa tactcactac cttttgatat
    34501 aatattttta tcaattatta ttatattcaa gttttgaaag gagtattaaa atgagtttat
    34561 tagttttcgg acataaaaat ccagatacag attcaatatg ttctgcaatt tcattagcac
    34621 atttaaagaa caaactagga ataaaagcaa cagcttatgc tttaggagat atcagaaaag
    34681 aagctaaata tgccttggat tactttaagg tagatgcacc tgaaatttta gataatgtta
    34741 gaatacaagt tagagattta aattatgata aagtagtacc tttaacacca acttcatcta
    34801 tattagaggc ctataacctt atggatgaaa aaaatgttaa aacactacct gtaacttatg
    34861 atgatggaac ttttgctggt atcattacta tgaaagaaat agctaaaaat ctacttcatc
    34921 aacactttac aactatacac acatcactat caaacatttg taaaaacctt aatggtacta
    34981 ttcttgtgga ctgtggtgaa gatataaaag gtagagtagt cactttatca tttggaatgg
    35041 agactctaat agagacttta aaagaaggag acatagctat tgttggagat agatatgata
    35101 gtattgaata tgctattgat acaaaagtta aacttttaat acttactaat catacagaga
    35161 tttcaaaaga tttgctagct cttgctaaga taaatggagt gtctgttgtt tctgttgaaa
    35221 gtgacaatta taaaacttct aatgtaataa atcaatgtag tttcttagac tctatagaag
    35281 ctacagaaaa tttaattaca ttcaaagaag atgattatat ggatgaaata aaagagatta
    35341 tgctagaaac aaacttcaga tcttatccaa tattagatga tgataataag tttttaggtt
    35401 tagtttcaaa aggtcatcta ttaaacccat ctaaaaagaa tgttgtttta gttgaccata
    35461 acgaatatgc tcaaagtgct gatggaattg aacaagcaaa catagttgaa ataattgacc
    35521 atcataaact tggtggtatt tctactgatg ttcctatgtc atttagagtt atgcctgttg
    35581 gatgcaatag tactataatt tatcaaatgt acaaagaaaa taatgttgag ataccttatg
    35641 aaatagccgg gcttctttta tctgctatat tatcagatac attattattt aagtctccaa
    35701 caacaactga tatagataag aaagcttgtg aagaattaag taaaatagca aaagtagaca
    35761 tggaaaaata cgctatggat atgtttaaat gcggtacttc tttagatgaa tatactatag
    35821 aagaaatagt aaatatggac tttaaagaat ttaatatgag tggacataga gttggtattg
    35881 gacaagtatt taccttagac atagactcta tatttgctaa aaaagatgag tttttatctt
    35941 atataaattc gactgattat gataaattaa ttctttcagt tacagatata atcaaagaag
    36001 gttcttattt aatctataaa gcagaagata gcttaattgc taacgcattt ggtgttgaag
    36061 gtgttcaagg cacatttgca ccaggtgttg tatcaagaaa aaaacaatta gtccctaatt
    36121 taactactgc aatcaaaaat tttaaataat ataaaatttt taaataacga aaactgtctc
    36181 aaatctatat ttgagacagt tttttattat atatatattg ataataaagt taaataaaaa
    36241 tccataaatt taaaattttt atgaatatat tttattatta ttgttatttt attcattcta
    36301 aaataggtaa aactcaatat ataaaaatac ttttgtcatt taaataaagc ctaaatagtt
    36361 tttaagatta ttttagacac gttttaagtc ataacagtat cagctattct aaatatcgtc
    36421 aaagtagccg cagttcctgc tgattgccca tttcgtatcc ctactgttgt agatgaaaaa
    36481 ttatttattg taaaagtagt cccaccaaat aaaaaaccag caaaatatcc agaaagtact
    36541 cctccgcctc ctggctcagt agtaagccct gccaaatctt ttcctcctaa aattgggaat
    36601 aggatagcga aagaatattg atttatactt gatgaacctg gttgtaatgc tactgaaact
    36661 gatatataat acacaccatt ttcttgtact gtaaacgtac catttgcatc tactgttata
    36721 cttgaactat ttcctattat tgtttgccaa cctgttatag catctccatt atttagtgtt
    36781 tgtggagatg gtgcatttac gaggaagtta gcaactggct gagaggaatt gcctgttgct
    36841 cctgttggac ctgttgggcc tgttactcct gtcgctcctg ttggtcctgt tactcccgtt
    36901 ggccctatac ttcctgtcgc tcctgtattt cctgttgggc ctgttgctcc cgttagtcct
    36961 atttctcctg tcactcctgt atttcctgtc ggacc
//
LOCUS       DAEOTL010000037        36616 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEOTL010000037 DAEOTL010000000
VERSION     DAEOTL010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.037"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            142..1533
                     /locus_tag="KRH82_002127"
     CDS             142..1533
                     /locus_tag="KRH82_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBG8655406.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1786..3579
                     /locus_tag="KRH82_002128"
     CDS             1786..3579
                     /locus_tag="KRH82_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8655407.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3660..5042)
                     /locus_tag="KRH82_002129"
     CDS             complement(3660..5042)
                     /locus_tag="KRH82_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBG8655408.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISLLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5300..5647
                     /locus_tag="KRH82_002130"
     CDS             5300..5647
                     /locus_tag="KRH82_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBG8655409.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5665..6699
                     /locus_tag="KRH82_002131"
     CDS             5665..6699
                     /locus_tag="KRH82_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655410.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6748..7797)
                     /locus_tag="KRH82_002132"
     CDS             complement(6748..7797)
                     /locus_tag="KRH82_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8655411.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8072..9607
                     /locus_tag="KRH82_002133"
     CDS             8072..9607
                     /locus_tag="KRH82_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655412.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9792..10478)
                     /locus_tag="KRH82_002134"
     CDS             complement(9792..10478)
                     /locus_tag="KRH82_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBG8655413.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            10603..11985
                     /locus_tag="KRH82_002135"
     CDS             10603..11985
                     /locus_tag="KRH82_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8655414.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIQEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12387..13655
                     /gene="eam"
                     /locus_tag="KRH82_002136"
     CDS             12387..13655
                     /gene="eam"
                     /locus_tag="KRH82_002136"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBG8655415.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPIYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13748..14104)
                     /locus_tag="KRH82_002137"
     CDS             complement(13748..14104)
                     /locus_tag="KRH82_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655416.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14255..15349)
                     /locus_tag="KRH82_002138"
     CDS             complement(14255..15349)
                     /locus_tag="KRH82_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBG8655417.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            15813..16634
                     /locus_tag="KRH82_002139"
     CDS             15813..16634
                     /locus_tag="KRH82_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBG8655418.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            16655..17851
                     /locus_tag="KRH82_002140"
     CDS             16655..17851
                     /locus_tag="KRH82_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBG8655419.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKYINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            18019..21417
                     /locus_tag="KRH82_002141"
     CDS             18019..21417
                     /locus_tag="KRH82_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBG8655420.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSIYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            21427..23100
                     /locus_tag="KRH82_002142"
     CDS             21427..23100
                     /locus_tag="KRH82_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBG8655421.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            23373..23567
                     /locus_tag="KRH82_002143"
     CDS             23373..23567
                     /locus_tag="KRH82_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBG8655422.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    23736..23969
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24046..25443
                     /gene="asnS"
                     /locus_tag="KRH82_002144"
     CDS             24046..25443
                     /gene="asnS"
                     /locus_tag="KRH82_002144"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBG8655423.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(25616..26791)
                     /locus_tag="KRH82_002145"
     CDS             complement(25616..26791)
                     /locus_tag="KRH82_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8655424.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYNTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEAEAKLKSECLRKII
                     ECCNFERDDVPLKCVTVSIGVYTKKIEKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            27210..28574
                     /locus_tag="KRH82_002146"
     CDS             27210..28574
                     /locus_tag="KRH82_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBG8655425.1"
                     /translation="MGEKKINNMNYSHNNYSKNTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NLAD"
     gene            28596..29087
                     /locus_tag="KRH82_002147"
     CDS             28596..29087
                     /locus_tag="KRH82_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBG8655426.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EEKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIII
                     DLE"
     gene            29360..30031
                     /locus_tag="KRH82_002148"
     CDS             29360..30031
                     /locus_tag="KRH82_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBG8655427.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            30116..30982
                     /locus_tag="KRH82_002149"
     CDS             30116..30982
                     /locus_tag="KRH82_002149"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBG8655428.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            31015..32517
                     /locus_tag="KRH82_002150"
     CDS             31015..32517
                     /locus_tag="KRH82_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBG8655429.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSVVLAGLTGIPVNVLIVV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFIGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            32647..33099
                     /locus_tag="KRH82_002151"
     CDS             32647..33099
                     /locus_tag="KRH82_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBG8655430.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            33259..34062
                     /locus_tag="KRH82_002152"
     CDS             33259..34062
                     /locus_tag="KRH82_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655431.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            34120..35007
                     /locus_tag="KRH82_002153"
     CDS             34120..35007
                     /locus_tag="KRH82_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBG8655432.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            35026..35874
                     /locus_tag="KRH82_002154"
     CDS             35026..35874
                     /locus_tag="KRH82_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8655433.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            35937..>36616
                     /locus_tag="KRH82_002155"
     CDS             35937..>36616
                     /locus_tag="KRH82_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBG8655434.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLELMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     EIELSRYF"
BASE COUNT        14288 a         4150 c         6262 g        11916 t
ORIGIN      
        1 aaaataataa taaaaaaatg aaaatacagg cgataatcta ttgagtaaac atagaaaaga
       61 tgatattata agtatgtgct aaaatggtta aagcaatatt aatattaaat ttaactataa
      121 aacaaaaggg ggcgtttttt tatgtcaagt acagaaagcg tatctaaaaa aagtggtcat
      181 ccgaagagtt tttggcttat ttgcatgaca attttgtggg aaagatttag ttattatggt
      241 ttaacagctt tattggtatt attttttaca gcaagtgtag ctcaaggtgg tttaggtctt
      301 tctactcaag aagcaacatc catgtttggc ttatttacag gtcttatata tcttacacca
      361 ttagtcggtg gctggttagc agataaagtt ttaggtcaac aaaaatgtat ttctataggt
      421 gcacttttaa tagcaatagg agatttcgta ctatttgctt catctacatc tattgccatg
      481 gtttgggtag gtctatcaat aattatttta ggaaatggtt tttttaaatc aagttgctca
      541 aatatagttg gggatatata tcctaaaact gatgtgtcaa gaaaagatgc agcatacagt
      601 ttattctata tggcagtaaa tgtaggagca tttatagctc caataatatg tggattgctt
      661 tctgataatg tatttgcagt aagaggagca agtggagata tagtatctta tggatataag
      721 atggcatttt taatttgtgg tataggcatg atgttaggta tgattatatt tacacttctt
      781 gcaccaaaat tattaaatga agtcggaaaa tatcctgtga ctaaaggtaa taaaggtgaa
      841 aaaattgagt atggaccact tactaagttg gagaaaaata ggataatagc aatggttatt
      901 ttatttttat ttgtggtctt attctggaca gcatactatc aaacacaaag ttcttttatg
      961 atttatgtaa gggataatgt aaatagaact ctatttggat ttgaaatgcc agtagcatgg
     1021 cttacatcac taaatgctat attatgtgtg gctttatgcc cagtattagc taccctatgg
     1081 gttaaattat ctcataccaa aagaggtgat ttctctattc cagttaaaat gggattagga
     1141 atgataataa tgggtgttgg gtttatagtt atggtatttg ctacattagc taatggtcca
     1201 gatggaatgg taaaggctag tatattgttt atagtattga cttatatatt tacaacagta
     1261 ggtgaattat tcttatctcc tataggactt gcaatgttca ataaattagc tccagctaag
     1321 tatgctacgt tgtctatggg agcctggtat ctaacaagtt tttttgcaag tttattatca
     1381 ggaaagattg ctggttttac agccacactt ggttttttac agatatttgg aggaatagca
     1441 acagttttaa taatatttgg tttaatatta ttgggaataa gaaatgtatt aacaagatta
     1501 atggctatgg atttactaac aaaagaaaaa taattcatga cgaattattg taaataaatg
     1561 aattacttta aataaaggaa gttacattta aatataaaat taaatgtaat ttcctctttg
     1621 attatgaaaa aaagctttac acaaatagat attataatta aaattataat tgtgataatt
     1681 agagtgtata agatttatat aaattataca aaaaatattt atgtaataaa ctttacatac
     1741 ttatatattt agttattcaa actattattt cgaggaggtc ttgttgtgaa tataaaagat
     1801 agattaagtg gattaagaaa atttatggaa gaaaaaaata tagatgccta tatgattcca
     1861 tcttctgata atcaccaaag tgaatatgta ggagattact tcaaatcaag agaatttata
     1921 tcagggttta atggttcagc agggacggtt attgtgacta aagacgaagc tgggttatgg
     1981 acagatggaa gatattttat acaggcagaa tctcaattag aaggaagtac aataaaatta
     2041 ttcaaaatgg gacaagaagg ttgcccaact acagatgaat atttatataa aaatattcct
     2101 gaaggaggaa ctttaggatt tgatggtaga gttatatctg ctagagaagg agctacatta
     2161 gctgaaaaat tatctaaaaa aggtataaag atagaatatc agtatgattt aatagatagt
     2221 atatggccag atagacctgc tttatcagat agtaaagcat ttttattaga tgttaaatat
     2281 tgtggagaaa gttttagctc aaaattagct agattaagag aaaaaatgag tgaaaaaggt
     2341 acttctactc atgtaataac tactcttgat gatatagcat ggttattcaa tataagaggt
     2401 ggagatgtta aatataatcc agttgtactt tcttatgcag taataacttt aaaagaagtt
     2461 tatctatttg ttgatgaaag taagttaaat gaagaaatac taaatgaact agctaaggaa
     2521 aatgttcaaa taaagccata taatgatgtg tatgaatttg taaaaaatat agacaaaact
     2581 gaaaaagttt tattagatgg aactaagctt agttatacaa tttacaataa tataccttgt
     2641 gaagttgaga aagttgatga gttcaatcca gtaatgtttt ttaaagctca aaaaaatgag
     2701 gtagaattag aaaatataag aaattcacat gtaaaagatg gtgtagcttt cactaaattt
     2761 atgtactggt taaagaaaaa tgtaggtaag atggaaatca ctgaaataag tgctactcaa
     2821 aaattagagg acttaagaag agagcaagaa ggtttctttg agccaagttt caatacaatt
     2881 gctgcatata aagagcatgc tgcaatgatg cactatagtg caactccaga gtcaaattat
     2941 aaattagagg cagaaggatt atttttagta gattcaggtg gacaatatta tgatggaact
     3001 actgatataa ctaggactac agttttagga cctataagtg atgaattaaa actacacttt
     3061 acttctgtag caagaggaat gataaatctt tctaaggcta agttcttgca tggttgtaga
     3121 ggatataact tagacatact atctagaagt tgcatgtgga atatgggaat tgattatcaa
     3181 tgtggaactg gacatggtat aggatttgtg ctaaatgttc acgaagctcc aaatggattt
     3241 agatggagag tagtacctga aagatttgat agtgcagttc ttgaagaagg aatggtaact
     3301 actaatgaac caggtatata tatagaaggt tctcatggta taagaacaga gaatgaaatt
     3361 gtagttagaa aagctgaaaa gaatttctat ggtcaattta tggaatttga agttgttacg
     3421 ttagctccta ttgacttaga tggtatagta ccagaattaa tgaataagga tgaaaaagat
     3481 tatttaaact ggtatcataa gttagtttat gataaaatat cacctttctt aactgatgaa
     3541 gaaagagaat ggttaaaagt ttacactaga gctatatagt ttgtactaga tacaataaaa
     3601 atcgaggtat tataatgcct cgatttttta ttgtatattt tattaacttt aaaaaatttt
     3661 taatttgata attctactaa ttttttattc attataagta gtataattcc aaatatcaat
     3721 aaaaatgatg gtatcactat gaagacttgt aacataccaa gttggtctat aatagcttgc
     3781 gtatagccag ataatttatt tgctgcaaat ttgcctaaaa accaaacacc cattagtaat
     3841 gaaatatact tttcaggcga aagtttattt accataccat acccgactgg agaaaagcaa
     3901 atttctccta tactttggaa tgttaaaaat ccaactaccc aaaatacact tgctttgtga
     3961 attgaattag ggtctgttcc tgtttgtata actgctacta tcataaacaa aaatgctatg
     4021 gctaatagta taaaacctaa gctcattttt tttggcacac ttaaatcgcc ttttttagtt
     4081 tgagataatt ttacccatac taaagcagag ataggtccaa gaataacaca aaggagacca
     4141 ttgtatgaat ctatccatga agtaggaatt tgaaaattgc caacagtaag atttatgtgt
     4201 tcctttgtat agagtgcaat agacatagag gcttggttat atgctatcca aaaaaatact
     4261 gtgaaaaaag ctaacaccaa tattactatt attctttttt tctcaatcaa agttaaaggt
     4321 cttgaagcga gcattttctt atattctagt gattttctta tagactctct cccgttaata
     4381 gggtcattat tcaaaggttt ataaaacttt ctgtttccaa atataaagaa gaataaacct
     4441 attagaaccg taattgatga aaataaaaat acatatctat atccatacat acttatagat
     4501 aatccgcttt tcatagcaaa ccattcatta gcaactaaac cgcatattaa agggccaaat
     4561 aaagtaccta gattagtagc catatacgta atagagaaag ctccatcttt tcttgggtca
     4621 tcattggtat ataagtttcc aaccatagta tgtaagtttc ctttataaaa acctattcct
     4681 aatccagata aaaatatcat gatgtttata tccatcttac tatttgctat gtatcctaga
     4741 aaataaccaa ttgaaaccat tagcattcca agtataatac agtttttggg acctaaaaat
     4801 ctatcactga cccatccacc aataactgga gagaaataag tccatgctaa aaaagatgca
     4861 agcattgatg cggattctgc tggtgttaac cctaaaccac ctttggagac ttgttcagct
     4921 aaaaacaata ataataccaa tttcatacca tagtatgcaa gtcctacaaa ggtaaatatt
     4981 gaacagcaga aatataaatc tctaggttgt ttaagttttt cttgcgtttt taaaactgac
     5041 atatgtcgag aacctccaga taaatagttt aacaaaattt taccatacta tatgagtata
     5101 tgtttttttc atatagacgt caacttgtaa gataatttaa ttaagtcgaa atatatgtaa
     5161 aaatagtatc atttttgtgt attcagtaat atttttttat gataatatat gttattatta
     5221 tattaaaata caaacatatt tatggaaagg atatgccaat ttagtagtta gattgattgt
     5281 ttggcaggtg ggatgagcta tgataagaaa gaaatctgaa ttacaagtag aagtaaaaga
     5341 aaatttaaat ggtggtatag gaaaggttaa gcttgaaaac ataatacaaa atgaagagct
     5401 taaaggaaaa ggaagactat ttaaaagagt agctttacca gtaggaagtt caattggtgt
     5461 gcatgaccat acaacagatt ttgaagtata ttatatacta aagggaaaag gtaaagtatt
     5521 tgataatggg gaatttgtag aagtaaatga gggtgatgta gtgtatacag ctgatggcga
     5581 aaaacattct atagaaaata taggagaaga agatcttgag tttgtagcac tagttttata
     5641 tatgtaaaat atggaggagg agtcatgaca ggcaagatag aagaaattaa ggacaagata
     5701 aatagatttt gcaactccaa tttaaatcaa gaatacaaag atataagctt taaaattttg
     5761 caaaaccttt tagataataa taaagagata attcattctt ctagagctga tatatggtct
     5821 tcagctatac taaatatagt tttagaacaa aatcttttat acaataagaa gcatccacta
     5881 catataacaa aaaaagagtt ttcaaaacaa ataggtgttt ctttaaatac tataaataat
     5941 aaatcgtctt taataaaaga tgtttgtagt attgactttt taaatcaaga tactatagct
     6001 atttctaatg tagaattttg ggtaaaagag actaattcca aatcaaagtc tgtagattta
     6061 gatttagaaa agaaaaaaat actatataaa agatatatta agctatcaca agatgcgaat
     6121 agtgatattg aatcaattag atatatggag gaagctgtaa atataggtaa aagtatgatt
     6181 actaaagaag ataaagaact tggattttgg aaaggtttat ctaccagagc ctatatgata
     6241 gcacttgaat cccttgctag aaagttagaa agtattaata atctaaagga gtccaaaaaa
     6301 gtattagaat atttaataga aattaatcct agtgatgagc agggaataag atacaaatta
     6361 ttaaatgtat taattagatt aaatgataga acttcaataa ataaattatt tgaactttat
     6421 aaagaagaaa aatctgctac atggatgtac agtaaagctc tttattactt taaaaataaa
     6481 agtatgtttt tggcaaatga ttctattaag gttgctagaa gtaaaaataa gtacgttgga
     6541 ttatatttgt tagattggcg aaatgctttt ggtagagaat ttgttacaga ggaagaaaag
     6601 gcagaagctg tctattacta tgatgaaaac atagtgattt ggaatgaagt taaaggttct
     6661 atggattggc tattaaaaaa aatgttggaa ttttcataaa aaaaactact ccttactttt
     6721 atataagtaa aaggagtagt ttttaattta tacatctagt tttaaatctt caggttttat
     6781 tagacctttt tttctcataa attctgaaat caacaaagtt acaatagcag gaagtataaa
     6841 attaagtaaa agtataccaa cccacataga tatacctcct tttccagcac tttgcatagc
     6901 agttactgtt ccaaattgtc caaccaatcc acaagtgccc ataccagaac caataggaat
     6961 attctccatt ttgaatattg ttgtagataa tggtccaagt aatattgaag ctacagtagg
     7021 tggtatccaa attttccaat tttttattat attaggtact tgcaacatag atgtcccaag
     7081 accttgtgcc acaaggccac caactccatt ttccctaaag ctcataacag caaagcctac
     7141 catttggcaa caacaaccta cagttgctgc cccaccagca agaccaccta aacttaacat
     7201 catacaaata gctgcactac ttataggtaa tgtaagagct attccaacaa gtgcagagac
     7261 taaagctccc attattatag gttgcatagt tgtagcttgc attattatat ttccaaatga
     7321 agtcataaaa gcagaaacag ctggaccaat aagttcagct acaagtactc caattagtat
     7381 tgttacagca ggtgtaacca atatatctat ttttgtttct tttgaaacta attttccaac
     7441 ctctacagca aaaagtgtag cgacaaatgc tccaacaggt cctcctaatt cattaccaca
     7501 agctccaaca agtgcacaag aaaatagtac aagtggaggt gcttgaagtc catacgcaat
     7561 agccactgct atagctggac cagtaacctg tttagcaaga gggcttataa cttcagtaaa
     7621 aagagaaata ttgaaattat ctcctaatgt attgaaaatt gttccaatta aaagggacga
     7681 aaaaagaccg agtgccatat aacttagtgc gtcaataaga tacctttgaa cagaaatttc
     7741 aatatttttt cttttagcaa atgatttgaa atttcttttt ttataattga tttccaattt
     7801 aaaatcctcc tcatataata taagtataat ttctttttaa ttaattatat aacttttcag
     7861 ctgacaagac aaatgttatt tcactaaaat tagactattg taatagtaag aaattaacat
     7921 taattttagt tttaaatttt aaatttatgg tttataatta gtatagggat attctgaaat
     7981 ataataattt tccagtttat cccaatattt aacttaggta gattgcttac aaaacaaatg
     8041 attatatatt aggctaaaag gaagtggata gatgatattt gtaaaaaata agaaatacag
     8101 aaaaattgcc ataattatat ctattcctat attgcttgtt gcgcagtact acctttttaa
     8161 atttggaata cttagaccaa tggtaaaggg agtagaaatt gaaattgtag atggggaata
     8221 tgttaaagat atagataaat atgtagtaaa attaaatgaa acagttactt tgtctacagg
     8281 tgaatatatt aaggttcctt cgtatgctaa aaatccaaat atttggttta atgtattgga
     8341 taactcaggg actttaaaaa tagatggaaa taaaatgaca gcattaaagg ttgggtattc
     8401 ttctgtgggt atcatgaaaa attcaagagt attaaaaaag gctactataa aagtagtaga
     8461 cccagaggta gaatcactag atatggagat taatggggat ttaaaacatg ttggtgatag
     8521 tgctactata gaaagtacaa tagaagttga ttatgataag tttaaaaaat catataagcc
     8581 agtttataag agtagcaatg aaaatatttt aaaaatcaaa ggaaataaag taagtgcagt
     8641 tggagttggt aaagctacaa tatatgctaa gtgtggaaat aaagaaattg agagaacatt
     8701 taggattcaa gctagagttg ctgaaataaa tatggatgat ataaaaatag aagttgacca
     8761 gaatgaaaaa ttgaaaccag atataataac ttctccacct ggtttagaac caccaaaaat
     8821 atattatgag ttagtagatt caaaattacc tgtagaaaga gcaataagtt taagtagtaa
     8881 tggaaatgtt gtagggctta gagaaggtaa agatagggtg agaataactt gtggagataa
     8941 atctaaagta ataacagtaa cagtagtcaa agaaactata acgaatgact atatacaaaa
     9001 cttggttggt tcacataaaa tagtaaacaa taaagttatt attaaacttg aatgggatta
     9061 tatgaaagat gtctttgatt atgatatata tcttaaagat aagttgtcag gagaatcatt
     9121 taagaaaatt aaatctataa ctataaatga aagtgattta ggtaagtcta acaaggtata
     9181 tgcgactata gaagtagata tgaagggtaa tcaaaatata gattttgata tttatgtcat
     9241 agggaaaaag gattcagata caactaagcc aagtaatgta ataaatatta ccaatggaaa
     9301 tggaaattca aataatgata ataatattaa agatatgagg gtagaaaata tatcagctaa
     9361 tgttgataga gataataatg tcattagagt taactggagt agtatatctc ataaggactg
     9421 tacttacagt atatatgtaa aaaataatac taatggagat ggagaattta ctctatatca
     9481 aagtgatata cagggaaatg agcatactat aagtattcct gaaggagatt taaatctaga
     9541 tatttatgtt gttgcaaatt ataatggaaa tagctctcaa aatagtgatg ttataaatgt
     9601 aagatagatt tgtatacaaa ttgaaagtgt tgagtttatt taaatattaa attaagaaaa
     9661 aggatagtat agggtaatta tactatcctt ttttgttaca atatataggt ttaaaatctc
     9721 tagtaatata aattataaaa agtcttattt acacaaatct atagatattt tttttattaa
     9781 tcaatattgt cttaaattga acttagtgca gcttctattg catgtattac tgtcgtatca
     9841 aatagtggaa tagaagtgtc attttgttta attaaaagac ctatttctgt acatcctaat
     9901 ataacagcct ctgcaccttg tttgccaagc ttatctataa tagataagaa agcttttttt
     9961 gaagattcag atataattcc taagcaaagt tcattaaata ttgtgtcatt tactattata
    10021 cggtcttctt catttggaat taagacttca attccattat taataattac atttttataa
    10081 aaatcttgtt ccattgtata tttagtacct aataaggcca ctttttttat ttctttttcc
    10141 cttaataccg tagcagttac atctgctatg tgaagtaatg gaatatgtat actttcttgt
    10201 attttatctg ataccttatg catagtatta gtacagataa caataaaatc tgcccctgcc
    10261 tcttgtaatt taattgcagc atcagctaaa attttggcgc ttttttccca atttccacta
    10321 gattggcatt cttcaatttc ttgaaaatct acactgtaaa gtatacattt agaagagtgt
    10381 agtccaccta atctttcttt tattactgta ttaataactt gataatatgt aatggtactt
    10441 tcccaactca taccaccaat taagcctata gtcttcatat tatacctctc ttatttattt
    10501 attttgaaat agctatttac aaatacaagt atagcatcta aaatagaagc atacaataat
    10561 aaaattgtat ggagtacaat tataattaag aggagtaatt atatgccaat aaattctttt
    10621 gaaaactatc ctatgacatg gaaaccaaaa ttagataacc gaaaaccacc aatatataaa
    10681 actttagcaa tgttattaga agaagatatt aaaagaggaa atttaaatcc tggagataaa
    10741 ctgcctccac aacgggaatt agcagatttt ctagatttaa acttaagtac aataacacga
    10801 gcatttaaac tttgcgaaga aaagggacta atatgtgcaa aagtgggaaa gggaacattc
    10861 atttcttctg atgtaaatgt aagtaataca ttattatatc aaacggaatc aaaagacata
    10921 attgagttgg ggacagttca tcctccgtat gagcaaaata catatattat tgactttatt
    10981 aaaaatgtac taaaacaacc agaaatggat aggtttttac aatacatgtc tccatctggc
    11041 acatatatgc aaaaaaagtc aattgcaaaa tggatagaaa gaaataatgt atacaccagt
    11101 gaagaaaata tattattatc tacaggaggg caaaatgcta tatgtgcaac tttactagga
    11161 ttatttaaag ctggtgatag aattgctaca gattctttaa gtttttctgg aattaagtca
    11221 atagctaaaa tgataggtat tcaattagtc ccaattcctc aagaaaataa tgaaatatcg
    11281 attgaatatc ttgaaagtta ttgtaaaaat gaaaatataa aaggcatata tcttatacca
    11341 gattatcata atccaacgac acatactatg tctgatttat ctcgtaaaaa gatagccaag
    11401 atagcaaagc aatataatat aataattatt gaagatgcta taaatagcat ttttagagac
    11461 ggtatacaaa ctcccatatt ttctttagct agtgataata ctatatatat ttttagtaca
    11521 tctaaatttt tatgtgctgg tcttagagta gcatttgtag ttgctccaaa acgatatata
    11581 gaaaatttag aaaatgcact atataatatg aatctaatgg tttctccatt tacagcagaa
    11641 atagtacacc gtttattata ttctcctatt atagataaaa ttatacaaga gaaaagagat
    11701 gcaattatag aaagaaatga agttgctgat aaagttttgt cagattataa tttgattggt
    11761 gataagaatt gcagttttcg ttggttactt cttcctgatg aattggatgg aaaatcattt
    11821 gaaatttctg caaaaaatct aggagttcaa gtatattgtg ctgaacgatt ttcagtagga
    11881 aactctacag ttccaaaagc agttcgtatt tgtgtaacag ctccaaaaga tgtagaagaa
    11941 ttagaaaaag ggcttaatat aataaagtca cttcttaaga gttaaattta ttttactatt
    12001 atttaattaa ataaataaaa aggcggagaa atttattata ataaacctcc gcttttatta
    12061 tttaatgaaa tactttactt tttattaaaa aatttaattt taataatctt gaaaatataa
    12121 tcgttttatg gtaaaataat tcttaaaaat agaaaaaatt aatcatttgt taaaaaaaat
    12181 gcataattta ttgtaattta ttgacgaagg ttgaaaaata ttcataaatg tgcgaaataa
    12241 cagaaaaaat gcaaaaatta attcaatttc atttgttata aaatctatat ggcaaaatta
    12301 aatctgccta tcagaatgat ataaacacat cagaaaggag gacgctatca aataatacaa
    12361 gtagttaact ttgatagcaa aaaattatga atgaacaaac tagaatatcc ttagagagag
    12421 ctgctgaatt aaaatcaaaa attgatgatt atattcaggc tagaaaaacg attaacagag
    12481 gtcttgaaaa agaagaagag ataaataaac gaaaacagaa aatattaagt atcttaaatg
    12541 gaactgaaga ggattggaat aactacaaat ggcaattatc aaatagaata acagatgtag
    12601 atactttatc aaaaattata actctaacta aaaaagaaaa agaatatata aaagaggttg
    12661 gtactcaatt tagatgggca atatctccat attatttgag tcttatagac ccagaagata
    12721 tatgtgaccc aataaaatta ctgtctatac caacacatat agagttggaa gatgaacaag
    12781 aagatttgga cccaatggga gaagagtata caaacccagc aggatgtata actagaagat
    12841 acccggatag attaataata aatgtaacaa atgagtgtgc tatgtattgt agacactgtc
    12901 agagaagaag aaatattgga caacaagatt ctcataagtc aaaagctatt atccaagaat
    12961 ctatagacta tatcagagaa aatgaagaaa taagagatgt actagtaact ggtggagatg
    13021 ctcttacatt aaaagatgat tatttagagt ggattcttag ccaacttaaa gagataccac
    13081 atgttgatta tgttagatta ggtactagga ctcttgttac aatgccacaa agaattacag
    13141 atgaattttg caatatgcta aaaaaatatc accctatata tataaatact cattttaatc
    13201 atccaatgga aataactaag gaatctaaag aagcttgtga aaagttagca aatgcaggag
    13261 ttccattagg aaatcaggca gtattattaa atggaataaa taatgataaa tttgtaatga
    13321 gatgtttaaa tcaagaatta ctgaaaataa gagtaaaacc ttattatata ttccaaagta
    13381 aacatgtaaa gggaacaaaa catttcaata catcagtaga tgatggtctt gaaatcatgg
    13441 agtatttaag aggatataca tcaggaatgg ctataccaac atatatagta aatgctccaa
    13501 aaggaggagg aaagactcct ttgcttcctc aataccttgt atcaaaagga acagattacg
    13561 ttatgcttag aacatgggaa ggaaaagtta taaaaatgga agatgaacct gctgtagata
    13621 taaagaaact tataaaagaa caagcacagg attaaaaaaa tatttaaagt ttataaaaag
    13681 aaacaacttt aaaataaaaa gaaaatggat gtcaaattta tatcaatttg catccatttt
    13741 ttattagtta tttattattt tgttgttgat taactaattc aagatatcca cttgggtgga
    13801 agtaatatat ctcagaagta ttttcattta caaagtaacc aatatcacca tctgcatctg
    13861 gtaaaaatac ataaccatta agatttttag cttttaatgc ttcaaaatca ctagcatttc
    13921 cttgatatat gtaatcaact tcattgttgt attttactaa aagttcttta gcttgttctt
    13981 gagtcaattt agtattttgg cttacaggaa cattcttttg agaatctgca taagaagatt
    14041 catttactgg tgcagttaat aacaaacaag ataaaactaa taaagatata agtgcttttt
    14101 tcatactaaa accctctttc atgtttaatt atataagatt cattacttaa taatattgta
    14161 tgtttcctat aattaaatat taccattaaa gagaataata ttacagttac acagctgtaa
    14221 cttttgatta caaaatcgta attaaattgt atttttattc catttgtatt ttatcatgtc
    14281 tacgatttac aaactcacag aagtatatct ttataacgcc catcacagga gcagatagaa
    14341 tcataccagg tataccaaag aatcctccac caacagtaac tgctaggatt gtaaagaatg
    14401 ggctaagacc tagttgtcca cctacgattt ttggctctat aaatgtaact tcaacttgtt
    14461 gaattattat taagtaaatt aaagaagtta aagcaattgt tggattggag aataaattaa
    14521 ttattacaac tggtgccata cctattactg gaccaaaata tggaaccata ttcatgacac
    14581 ccataagtgt accaaataat agtgcatatt cagattttaa aaagtaaaga ccaattccag
    14641 aaagtactcc aactataaaa gaatctaaaa tcttacctgt aaagtattta ccaatattta
    14701 aatttaagct ttgacatagt tctattataa agtctccata ttttttacct aaggaaatat
    14761 aaactacttt ttttgtaaac agtaagaatt tttctttttc taataatata tagaaacaaa
    14821 ttataaaacc taaaagaaat tgtactataa attttccaac tgaaaatgta gtgctaaata
    14881 tcccaccaag tgaaccaata agcaagttac taaatttagg cattacactc ataattttgt
    14941 caccatactc ttttaatgta ttagggtcaa ctgattgtaa actcttacct aagtcgaata
    15001 agaattgctc tgttttatct atgtatgtag gaatttgagc aactaaatca gctaaactat
    15061 ttactatgga tggaactgta aataatataa aggaaattag tataactatg agtacaccat
    15121 aagtaagaag taacgaatat attctcttaa aatttaattt gctttctaag aactttacta
    15181 gtgggttgaa tatatatgct aatacaaatg ctattataaa tggtgttagt agtgacatta
    15241 ataaacttat cactccaaaa aaatatttgt aattatcaat aactttaatc aagatatatg
    15301 aaacaactac agtgagtaca atatttagat aaattttttt atcttgcaaa ataacacaac
    15361 ctttcttata tttattaaat ttagatatac ttaaatctaa gttaaagtta atatttatag
    15421 cttattatac aataaaaagc agtattaata tagtatgatt aatatgaaat tataaatacg
    15481 ttaaaacttt atgtttatag ctaaaataat aaaaattatt tatattgtgt ttatatataa
    15541 tctaaaatga aaaaaagtgg tgcctttgat taaactaagt ttttataatt taaattttgt
    15601 acaataagct atcttttatt attctttaaa atatatattt catttaatta tgacaaataa
    15661 agataaaaat taaatatttt agaggtgatt ttatttagat atagaatttt agaataatac
    15721 tatacaaatg tattgtatta ttatttttat atcaaaaata gtaataaagt ctatatacat
    15781 ttagaaaata ctgtttaaaa ggagtaggat ttatgataaa aaaagagata tctaacttta
    15841 gaggaagtag tgattatgta gtatcaccag aattgatggc atcagttaat gttgctattg
    15901 ctcttgaaaa gccacttttg attaagggcg aacctggaac aggtaaaact atgctagcac
    15961 aagcaatttc aaatgaatta aaaaaagatt tagtaatttg gaatataaaa tcaactacaa
    16021 aagcacaaga agggctttat gtatatgata ctgttcaaag actttatgat agccaatttg
    16081 gaggagaagg tgtagatgat attagcaagt acataaaata tggtaaacta ggagaggcct
    16141 ttagctcaaa tcaacaagta attcttttaa tagatgaaat agataaggcg gatttagaat
    16201 ttccaaatga cttgctttgg gaattggata aaatggagtt ttacataaat gagacaaaag
    16261 aaactgtaag agctaaacaa agaccaatag ttattataac ttcaaatgcg gaaaaagaac
    16321 ttccagatgc ttttttaaga agatgcatat ttcattatat agaatttcct gatagagaca
    16381 tgatggaaga aatagttaaa gtacattttg ataaagtaga agaacaccta ttggaacaag
    16441 taatgactac tttttattgg attagaagtt taaaggacat acaaaaaaag cctagtacat
    16501 cagagttaat agactggata caagcattaa ctttgagtgg aatgcctatt gaaaaaatag
    16561 aaaaagaagt tccttttgca ggaatactac ttaagaataa tgaggatatt gaatctatgc
    16621 aaagacactt atagttaata ggagctggat aattatgttt attgaatttt tttatttatt
    16681 gaggtcaaga ggattaaatg tatctttaaa tgaatggatg actttaattg aagcattgga
    16741 taaaggactg tgctattcaa acttttcaaa tttttactat ctttgcagga tgattttaat
    16801 aaaaagtgaa agtgattttg ataagtttga tgcagtgttt ttggagtatt ttaaaggtat
    16861 agaacaccaa gaagaaattc cagaagagat tatgaattgg cttaaaaaac cagatataga
    16921 tttagaagag tttgaaagat tagaacaaaa tccaaatata aatcttgata aattaagagc
    16981 taaattggag gaacgaataa aagaacaaga ctctcctcat aatggtggta attattggat
    17041 aggcacagga ggcacttcag agttaggaca ttcaggaaaa gggcaaactg gtatacgtat
    17101 aggtggaaat tctacttatg gtagagctgt tcttgaagtt gcaggagaaa gaaaatacag
    17161 agattttaga gatgatgaag ttttaaatat gcgtcaattt caagttgcac taaagagact
    17221 tcgtcaattt tctactagaa tagatgctcc aaagacagaa cttgatttgg ataagactat
    17281 tgaagagact tgtaataatg caggatattt aaagttattt tttgagaagc caagaaaaaa
    17341 tacagtgaag cttttattgc ttatggattc aggtggttca atgagagggt atagcacttt
    17401 atgtaataca ttatttcagt ctgtaagtaa atcaaatcat tttaaagatg taaagatata
    17461 ttatttccat aactgtattt atgatagatt atttacaaca cctgaatgtt ggttaagtaa
    17521 atatattaat actgaatgga tattaaaaaa tatagataaa aactataaag ttataattgt
    17581 tggagatgct tctatgtcgc cttctgagtt gcttcatatt ggtggtaact atcgtggtcc
    17641 atataattac acacctggta tagagtggct taaaaggttt aagagaaagt acagtaaaat
    17701 tgtatggatg aatccagaac ttagagatgg atgggattca attaattatt ggtatcaaac
    17761 tcaaagaatg atacaaagtg aatttaatat gtttccattg actgtaaaag gtcttgagaa
    17821 agcattgaaa aatttaatgg tttcaagata aagtaaatat aaatgatggt atgatttatt
    17881 caaaattgta ccatcattat ttattttttt taatatatct attataaatt gtataactga
    17941 aacttaaaaa attatatagt ctaatacatt ttagactcac acaaaacata tacattaata
    18001 ataattttag aagtcgaggt gattataata aattatgaat taattgtaaa atacaatgga
    18061 gatatattga ggttagaaga agaattaggt gtatcagtag agatacttaa ttcatcatat
    18121 gcaataataa catcaagtaa tgaagaagat gtaaatatac ttttaactta tccagaaatt
    18181 gaatttatag aaaagccttt tatattacag actcaggatg tgcaaagttt ttcaagtaca
    18241 ggaataacag gatttaaaaa tagaactggt ttaactggaa aaggaactat aattggtata
    18301 attgattcgg gaatagatta tactctacct gtgtttagag atagtgatgg aaggtctaag
    18361 atattatatt attgggacca atctattcaa ggaaatccac cagaaggttt tagagaagga
    18421 acattatata ctaatgaaga tataaataat gcaatagatg gaagtatata tatacctatt
    18481 tcaacaacta gcttacatgg gacacatgtt gcaggtattt gtgcaactat tgcaagtgat
    18541 gccagaataa tagtggttag agttggaaat atacagaccg atattttttc gagaagtaca
    18601 gagtttatga gggcaattaa atttatttta gatagggcat tagaattaag aatgcctgtt
    18661 acattaaata taagttatgg aagtaatgaa ggttcacata gaggaacatc tttatttgaa
    18721 caatatatag atgatatgtg tttattttgg aaaaacaata tagttgtagc agctggaaat
    18781 aatgcagata aaggaggtca taaaaggatt aggcttcaaa ataatattac agaagaagtt
    18841 gagtttatag ttggggaagg agagcgtata ttaaacataa atatatggcc agattttgtt
    18901 gatgatttta gtgtacattt ggtaaaccca tcaaataatc aaacacaagc aatctctcta
    18961 acttcaggtg agataaggaa tactttgggt gaaactagaa taactggtta tttttaccct
    19021 atagcaccgt attctctcac aagaagagtt actctacaat taagttcaaa tacacagata
    19081 actcctgggt tatggaaaat tgtatttgaa ccaatagata tagtaactgg taatgtaaat
    19141 atatatttgc caacttctga aggtctaaat agaaatacta gatttctgat tcctactcaa
    19201 gagcttactg taacagttcc tggaacagca agtagagtta taacagtagg tagttttaat
    19261 tcaagaacag atatagtatc tatattttct ggtgaaggag atacacaatt aggtgttttt
    19321 aaacctgatt tattagctcc aggtgaagat atagtatctt ttttaccagg aggtacaagt
    19381 ggagcattaa ctggaactag catggctaca cctcatgtta caggggtttg ttcattgttt
    19441 atggaatggg gaattgtaaa tggaaatgat ttatttttgt attcacagaa attaagggca
    19501 ttacttctaa agggagcaag gagattaagt aatcaatctt atccaaataa ttcatcagga
    19561 tttggttttt taaatttatc agatatagat ttgtacactc tatctaatat aaatcaagat
    19621 ttagaaacag aggatattgg atatagaagt attaataagt catttaaaga tgaggaaaat
    19681 agttataagt ttatagatgg ttataatatg caaatacata atgacttaga gaatgaaatt
    19741 tatataagta aaaatgcaag tagacaatca ggaatactat caggaataga tatagtccat
    19801 actcctgaat ttgaagaaga actagctggg ttaggtatga gtcaaaggtt ttttaagata
    19861 agtgattcat taggtgtact atctataaat aatacagact ataatagcat acaacgagtt
    19921 ttgcaacttc cttcaatcat aagaactgta tcgactacaa agatgacatt acttggagaa
    19981 attaatcgag gtacttttgg aggtgtagtt gcaacagaag aaatgggcgt aaatttcttt
    20041 aaaaataatc ctaatattaa tataacagga agagggactc taatatcaat tgcagataca
    20101 ggaatagact atctacaccc agattttatt tatccagatg gcacttcaaa aatagtatat
    20161 ttatgggacc aaacaaaaga aggaactcct cctgatggtt tttatattgg gacagaatat
    20221 acacgagaag atataaatcg agctatcgca gaaaatgacc ctagtctatc tcaggatgaa
    20281 gttggtcaag gaactatgtt gagtgggata tgtgcagggc ttggaaatgt aaatagtgaa
    20341 tatgcaggta tagcagaaga ttctgagcta ataataataa aactcggcaa gatagatgat
    20401 ttttataata gtgcaatgtt gtttgctgca tctcagtatg catataaaaa agcttttgaa
    20461 cttggaagac cattagttat aaatatgtct ttaggtacca gtagcctagc aggtttaacc
    20521 aataggagta atagtgaaaa agcgttcttt actagagggt tatgtataac ggcaggagca
    20581 ggaaatgagg gcaatacaca gacacataca tctggaataa taccatatgt tggaggttct
    20641 gttgaagttg aattagagtt aaatgaagac gaggaagaat tatcattaga actttggtta
    20701 aatagaccag ataaagctga tgtaataata gtatctccca ctggtgaaga aagtaaaagt
    20761 gttggaattt caaattataa taaagtaaca ggtttatttg atttagaggg gactgaatat
    20821 tctataacat atatataccc aacaactttt tctggacagc aatttactaa tgttacttta
    20881 aagaatgcaa aaagaggtgt atggaagatt cgattagtag gagtttatat tataacagga
    20941 agatataact tataccttcc aaatagagaa cttttaaaaa gtggaactag atttagagag
    21001 gtagaccctt tttacactat aaattatcct gcgattcaag atgatttaat aaccatagga
    21061 gcctacaata ctattaatgg tagtttatgg caaagttcat caagagggcc aactattgaa
    21121 gacaggttaa aaccagatat agtagcacca ggtgttaata taatagctgc ttatcctggg
    21181 aacacgtatg caactataac tggtacagca gcagcaagtg cacatgcagc tggtgctgct
    21241 gcaatgtatt ttcaatatac ttttgttgac ggtagatatc caaaccaagc atatgtgcaa
    21301 aaaataaaaa cttttatgca agctggtgct agaaaagatt caaacacagt atatccaaat
    21361 acaaattctg gatatgggct cttggatgtt agaggaatgt ttgatgtttt aagataggag
    21421 ggatttatgg aaaaatctta ttgtataatt tatcaaggtg atatagaatc tgccctacaa
    21481 gaaaatggaa taaataggta tatggtttta aatagtcagc ttgcagtaat atatgtacct
    21541 ttagattttg atgaaactat tttaaataat ataatacaag ttgcttggtg ggaagaatct
    21601 gaaccaatga gcagtctaat tgaaataact aataatgtaa ataatggaga aaccattaca
    21661 acagcagctg aaactgatta tatttatgaa aatccatata atgatataac agggagagga
    21721 attttattag cagttataga ttctgggata gattatttgc atcctgattt tataaatgat
    21781 gatggaacta gtaaagtttt atatttatgg gaccaagaag caaatacaaa tccacctcca
    21841 gaaggtttta tttttggaag tgaatttaca agaagtgagt taaatatagc cataaataga
    21901 aatgatggga gtttgagtca agataatata ggtactggaa ctttagtttc tggtatatta
    21961 gttggaaatg gaaggataaa ttctcagtac agaggtatta ctacagaatc agacttaata
    22021 gtagttaaat taaaatcata tacagatact tattatgctg gaaggataaa ttacagtgtt
    22081 tcagattttt tagcagctat aacgtatgtt actaacatag caagaacaga aaataaacca
    22141 ctgataataa atttgactat tggagttaag tcaagtgctg tagcaactac ttcaatacta
    22201 gatactttta atatattgag tagtgctggt gtggtagtag tgagtggtgc aggaaatcaa
    22261 gggaatacag atattcatta ttctggcaga tttagcagtg tgggagaagt tcaagatgta
    22321 ataatacaag atggagatga ctatgctctt gatataacac taaatacgaa tggtccagat
    22381 aaagtgggag cacagataat atctccttca ggtgaagtta gtcatgatat aaggtattct
    22441 ccagactttt atatatatag aggaaaattt aacttagaaa atactactta tgcaatgaga
    22501 tttatttatc catatattac ctctggaaaa gaaaatttgg agataagatt aagagatata
    22561 aaacctggag tatggatttt aagattgact tcagaactta taataaatgg agaatatgac
    22621 atatacttgc caaataaaaa tttgatagct ccagacacaa ggtttttaga ccctgattca
    22681 gtagctacta taactatgta tgctgctagt gatgatgtaa ttacagttgg tacatttaac
    22741 aataagactg atagtatgtg gattggttct tcgaaaggac caattagagg aagaggaatt
    22801 aagccagata tagtagcttc aggtgtagat ataatatcca catataaaaa tggaacatat
    22861 aatacaggaa caggaacagg agtgagcagt tctatagtca caggtgtttt agccttattg
    22921 atggaatact tagaaaaaca ggataatgta ccgagattat cattgtttac acaagtttta
    22981 aaaacatatt taatattggg tgctacaaaa cttgagatat atacatatcc aaatgtatcg
    23041 cagggatatg ggattttaaa tttaaaaaat acgattcaac agatagcaaa tactctatag
    23101 ataagaacct atgtaaaatt ataattgatt attagtttaa ttgtatcaaa tactttagat
    23161 agagtagaaa aatagcataa aaaataaata tgaaaattaa aaaatagttt tatattttga
    23221 atacacaaag taaatatttt gtatataaat aggtataaat taagtattga aaagatatga
    23281 tgttaattta aaaatcatta taatttagac ttatgaattt tatttgtaaa attgctaaaa
    23341 ctattacaaa ataaataata gaggtgatag ttttggaaag taaaaaggca agagcattaa
    23401 aaggtaaaga taataaaaga cttaaaagtt cacttttagt tggaaatgag tcgacagcag
    23461 catgggctga tgttgaaaaa ttaaaacctc atagtaaagt ttcaatacct tcaattaagg
    23521 gtgtcgaaga agcaaaagac tgggttgaca atggaagtaa attataaaat tttggaaatt
    23581 gaagtaataa agaagtaatg aagataagta tttattatca ttatgtaagg tagaattatt
    23641 atattttaaa taacaatcag tatcaattat ataaatttat tgactaaaaa tttataaatt
    23701 ggtataattt tgttaattag cagaaataat aaaagataaa tactgtgaag agaagagtag
    23761 atataaaatg tagttctagc gagttgagga tggtgaaagc tcaatacgag gtttatattg
    23821 aagaacatct tggagtttct aatcgaaagc ttatttagta agtagactta gacggaaggc
    23881 accgttatag gctttaagca ttgcttaact aagaggtcat tatgacaact agggtggtac
    23941 cgcgagagta atagtctttc gtccctttat atagggatga agggcttttt ttattgaaat
    24001 tatatttaaa agaaattaat aacaattata ctaggaggat ttaaaatgca aaaggaattt
    24061 ataacagtaa aagaattgta cagagaaaaa gaacagtaca tagggaagac tgtaaaagta
    24121 gctggatgga taagaacatc tagagtatct aaaaattttg gatttataga gctaaatgat
    24181 ggaagcttct ttaaaaatat gcagatagta tttgatgaga aagtagaaaa ttttaaagag
    24241 gtaggaaaat tagcaataag ctcatctata cttgtagagg gagagttagt atctacagaa
    24301 ggggctaaac aaccagtcga aatacatgca aaaagcatag ttgtagaagg ggaatcagat
    24361 agttcgtatc cactacaaaa gaagagacat acgcttgaat atttaagaac gatagcacat
    24421 ttaagaccaa gaagtaatac tttttcagct gtatttagag taagatcaat agctgcctat
    24481 gcaatacaca aattcttcca agaaagaaac tttgtatatg cacattctcc aatcataaca
    24541 ggtagtgact gtgaaggtgc aggagagatg tttagaataa caactatgga tttaaatgat
    24601 attccaaaaa ctgaagatgg caaaatagac tatactcaag atttctttgg aaaagaggct
    24661 aatttaacag ttagtggtca attaaatgcc gagataatgg cactttcttt tagaaacgtt
    24721 tatacttttg gacctacatt tagagctgaa aactcttata caggaagaca tgcttcagaa
    24781 ttttggatga tagagccaga aatagttttt gcagaccttg aagataacat ggaacttgca
    24841 gaagatatga taaaatatgt tataagctat gtattagaaa atgctcctga agaaatggaa
    24901 ttttttaata gttttataga taaaggattg ttagaaagat taaataagat agtaaactct
    24961 gagtttatta gaataacgta tactaaagca gtggaattat taattgaatc tggtcatgaa
    25021 tttgaatatc ctgttgagtg gggatgtgac cttcaaactg agcatgaaag atatataacg
    25081 gagcaaatat ataattgtcc agtgtttgtt acagattatc caaaagatat aaaagctttc
    25141 tatatgagaa tgaatgaaga tggtaaaact gttagagcaa tggatttact agttcctgga
    25201 gttggagaaa tcgtaggagg ttctcaaaga gaagaaagag aagatgtatt gttagataga
    25261 attaatgaaa tgggattaag agaagaagat tattggtggt atttagaact tagaaagttt
    25321 ggtactgcta ctcactctgg atttggtctt ggatttgaaa gaataattat gtatatgaca
    25381 ggtatgtcta acataagaga cgttatacct ttcccaagaa ctcctaaaaa tgctgaattt
    25441 taataattat atataataaa acctatataa ctttaagtat aaacactaaa atgacttgca
    25501 tatttatcta ttttagagat atgcaagtta tttttattgt actataaata tataatttga
    25561 ttacttttat tttgcgatat aatacttata ggtttatgta atagtatgta actttttaat
    25621 aaaatgcaac acaattacgt ccttgttctt ttgcagtata tagagcctta tcacaattac
    25681 ttataaactc atttaatgtt attgtctttt caattttctt tgtataaact ccaatactaa
    25741 cagttacaca ttttaaagga acatcatcac gctcaaaatt gcagcactct ataatttttc
    25801 gtaaacattc tgatttaagt ttagcctctg cctcattaca gttaaaaata catataaaaa
    25861 attcctcacc accatatcgt atagcatgtt cattttcaga acttgtaaaa tctaaaatta
    25921 ctttggcaat attttgtaga caatagtctc ccttttgatg tccataatta tcattaaatt
    25981 gtttaaaata atctatatct atcatcattc cagttatagg ttcttgattt gcatggctga
    26041 ttaatttttt ttgtagaata tcttcaaggt acctacggtt gttcatttta gtaaggtcat
    26101 ctgtcataac tttgtcgtta agtaaattat ttatatgaga tatttcttca tattgttgac
    26161 taattaaaag tttatcatag taagtaaata cacgatttct atatagcatt gtagaaacaa
    26221 aaatggcaag ggatgttata aaaaatgtgt tgacaatatt actaaactca ttgcctggta
    26281 tagtttgaat cccaggtaag aataaattaa gaaacaaaaa gcatcctcca aaaactatta
    26341 ctgattctcc aaattttaat actgagaaag ctgcagctgc taacataata taactaaata
    26401 cacttaggtc atttccacct aactggtcaa gtagagtaat tacacaaccc cataggcaga
    26461 aaaaagtcac ataaattatc cataaattta tataaaacgt acagcaatcc ttttttttat
    26521 tccaaaggta agaaaataca aacataaaga cagaagatac acaaaatagt gttacataca
    26581 tataaaaata ccattggcgt cttggtgtga caaaagggcc tccttctcta gctgagattg
    26641 atatcatcat aattatttga gatattacta ttattatgca aatgatttta cccgtattat
    26701 aaagataatt gcagagttct ttctcaacat tgtctttgtg ttttttgtct agaggaaatc
    26761 caaaaaattt ttttattttt tctaagttca tataagcctc cattaaaaat aaagcataaa
    26821 aataagtatt cctttctatc attagatatt tggaatactt cgtttatgat ttaattatat
    26881 caaaatatat tgtgtgtaac aatctaaaat tgtgatagat aaaatttatt agataatgtc
    26941 gagtaacttt attgattaat actttattat aattaagatt tacagatagt ttactactga
    27001 aaataaagaa tagaataaat ttaaattaag cataataaaa tataaataat aaagttcgca
    27061 ttaacaaact atttaaatat caagacctgt taaaaaacaa cagcaataaa caaataaaat
    27121 agataaatat atccaattaa ggtataatta agttttatat gatatagtta tatttgataa
    27181 tttacaatag taaaacttgg agggaaaaaa tgggtgaaaa gaaaataaat aatatgaatt
    27241 attcacataa taattattcc aaaaatacag gtgaaccaac tagaaaaata aaaaatagcc
    27301 atatcactct taaaagtaaa gaagaaaaaa tttgttctag ttgcaataaa gaaaataata
    27361 ctaaggataa ttactgtaaa ttttgtggaa atgaacttta tgaaatagca tcattaagac
    27421 cacttgaaac aaaactagac ttgaaatcta aaataaaaga gctttcatat catgcaaata
    27481 aaagaggtgt atttttaaca acatttacaa ccatatttat attgtttatt attgcattga
    27541 tatttaaagc tattataact attcaattta atgatattag ttatttagta aatccagcac
    27601 atataatcct agctctcaac ttgggtcaaa ttagtgtatc tatgtctacc atgatgggtt
    27661 ctgggtttat aaatgccaat ataggtttgt tgatattact tataatccct attttggtat
    27721 tattaatatc aaacctaatt tttatgagaa aaagatgtag agattcaaaa actgtattag
    27781 caaattctct aggagttgga attttttatg gattagtttt agctatttta tctattttta
    27841 ctaatgtaaa aactagttca catagtatgt tagaatatgg atatgcatta gaatatagtt
    27901 atgaattttt tagtgttctt ttaaatggat tcgtattagg gtttatatgt acatacataa
    27961 ctacttataa aaaaagttat gaaaaagaaa atatgtattt atctcttttt tcaaattcta
    28021 taagaacatt catattaggt tatgttttag tattagtaat actattggta ctaactatat
    28081 ctgatagtag ttacttaaat gaactagata tgagtagtta ttcaaatgga ttaaatttat
    28141 ttactatact cccacaaata gctagttata tgtgggcttt tgcaaatgga atttcagtaa
    28201 ccataataaa ctcaacagta tcaatgttta ctttaagttc ttcatcttta tttggagata
    28261 ctaaattaat gttttatgca atgggagcat tgtctatgtt aatattatta ttaaatggat
    28321 acaagctaag atttaagtat aatacagata gtataagacc tataatagta tttagtatat
    28381 attatgcatt tttgatggga atattggctt tatttagtac atttatacta gatagtaata
    28441 ttaatttctt taatacaact aattatggaa caactttaat aatgcaattt aaagtcttac
    28501 aagctattgt gatttcattt gtatatagtt ttgtgatatc tttaatagga tataagctaa
    28561 atttagctga ttaaatatga ttggagggaa tttctgtgga aggaaatact aataataaag
    28621 tagatgataa attttctaag gttaagaaaa agtttggtag tggaaaattt aaagttgaat
    28681 tatataaaga aaaatcaaaa ttaaatagag agattgatga tattcaagaa gagaaagcaa
    28741 agatattctt ggaaatggga atactgacat atcaaaaaat tagagaagat tctattaatg
    28801 ataatagttt tgataaattc tgtgatgagt tactagaact tgataagtta atttatgaaa
    28861 aaaatatgga aattaatgaa atggaaatgg cagaaagtaa tgtaacttgt gagtgtggtt
    28921 atgttggaaa tgtaaatgat aaatattgtg ctgaatgtgg taaaaaattt gaattggaaa
    28981 atgaatgtga tgattttata atttgtggtt attgtgaaag tgagatagat acagaggctg
    29041 aattttgtcc atgctgtgga agaaaaatta taatagattt agaataatat tgggaaacct
    29101 atgtatagta tacatgggtt tttttattga aattatttaa atggacttat aacagtagtt
    29161 atataaaatg aaaataaaca ccaaaaaaat gaaataaaat ttcttttaaa tgtaaaaaac
    29221 aagctaatat ataaaataaa tcagtaaaaa tatagatgca agaaaaaaat atgaaaaaat
    29281 attgcaaaga aaaagttttc atgttattat taatacataa atcaagaaaa taaatttcag
    29341 aaacgaggta atttaaaaaa tgctagataa ggtaaaggga agattaatag tatcatgcca
    29401 agctttagaa gatgaacctc ttcatagtcc ttttataatg gggagaatgg ctaaggctgc
    29461 tatggaaggt ggagctgttg gaattagagc tcaaggagtt gaagatatta ttgaaataaa
    29521 aaaagttact ggacttcctg ttataggtat tataaagaga aactatgaag attcagatat
    29581 atatataacg ccaactaaaa aagaagttga tgaactttta acaacagggt gtgaaatgat
    29641 agcattagat gctaccaata gagttagacc aaataatgaa gacttaaaag aacttataaa
    29701 gtatataaaa gaaaacggtg ttctagtaat ggcagatatt tcaaattatg atgaggctat
    29761 caaagcacaa gagtacggtg tagattgcgt ttcaactaca ctatctggat atactccata
    29821 tactaaaaca ttagaaggtc cagattttgt attaatggaa agattagtta aagatttaga
    29881 aatacctgta atagctgaag gaaaggtaaa tactcctcaa gatttaaaaa aggtctttga
    29941 gttgggtgtt cattcatcag tagtaggttc agcaataaca agaccacaat taataacaga
    30001 aaaatttgtt aaagcaattg aaattaatta aaaattaatt tataaattaa aaaattatta
    30061 tatttaacta tatttgaaaa ttaaaattgg aggtaaagat atgagaacaa cagatatgaa
    30121 gggaatttat tcagcattat tagtttcatt tgataaggaa ggaaatataa atgaaaaagg
    30181 gttaagacaa ataattagac acaatataga tgtttgtaaa gtagatggtc tttatgtagg
    30241 aggaagtaca ggggaaaact tcatgctttc aactgatgaa aagaaaagaa tatttgaaat
    30301 agctaaagat gaagtgaaag aagaaataaa attaatagct caagttggtt cagttaattt
    30361 aaaagaagct gtagaacttg ctaaatttac aactgattta ggatatgatg caataagtgc
    30421 tgttacacct ttttactata aatttgattt tgaagaaata aaacactatt ataatacaat
    30481 aataaattct gtagataata gattaataat atactctata ccatttttaa ctggtgttga
    30541 tatgagttta gaccagtttg gagaattatt tgaaaatgaa aaaataatag gtgttaagtt
    30601 tacagcagca gatttctact tattagagag aatgagaaaa acattcccaa ataaattaat
    30661 atttgcagga tttgatgaaa tgatgttacc agctacagtt ttaggtgtag atggggcaat
    30721 tggttctaca ttcaatgtaa acggtgtcag agctagacaa atattcgaat taactaagaa
    30781 tgaaaaaata tcagaagcac ttgaagtaca acatgtgact aatgatttaa taacagatat
    30841 attaggaaat ggcttatatc aaacaattaa attactactt gaagaacaag gtgttgaggc
    30901 tggatactgt agacaaccta tgaaagaagc aactgatgaa atgaaatcaa gagcaaaaga
    30961 aatatacaga aagtattttt aataaaatac ttttagtatg ggaggattag tcaaatggta
    31021 ggatttactt ggatagattt tgcaatacta gtggtttact tattggcagt tttatttgca
    31081 ggattgttat tttcaaaaaa ggaaatgaag ggaaaagagt tcttcaaagg tgatggaact
    31141 attccgtggt gggttacatc agtatcaata tttgccacat tattaagtcc aatatcattt
    31201 ttatcattag caggaaattc ttatggtggt acttggattt tgtggtttgc acaattaggt
    31261 atgtttatag caataccttt gacaataaaa tttttcttac ctctatatag taggttagaa
    31321 atagatacag catatgaata cttagaaatg agatacgaaa gtaaaggtct tagagtactt
    31381 ggagctttga tgtttataat atatcaaata ggacgtatgt ctatcataat gtatcttcca
    31441 tcagtggttc tagctggtct tacaggaata cctgtaaatg tattgatagt agttatgggt
    31501 gtaatagcaa taatttattc atatacaggt ggattaaagg ctgtcttgtg gaccgatttt
    31561 atacaaggta tggtattaat agtaggtgtt acagggacat tgttctattt aatagcaagt
    31621 ataaatggtg gttttggaac agtaatggat actcttacaa ctggacacaa gttcttagca
    31681 agtaatgaag ttatgtttga taaaaatata ctatctacaa gtgcatttat aatatttatt
    31741 ggagctggtc ttaatacttt ttcatcatat gtatcgagtc aagatatagt tcaaaggttt
    31801 actacaacaa ctgatataaa gcaacttaat aaaatgacat atggaaatgg tgttttatca
    31861 atgggacttg caacagtatt ttatctaatt ggaacttgtt tatttatata ctatactcaa
    31921 aacccagatt tagctcaaac agttcaacaa gaccaagtat ttgcatcata tatagcttat
    31981 gaattaccag tgggtataac aggaatacta cttgcagcga tatatgcagc ttctcaatca
    32041 actttatcga cagggcttaa ttcagttgct acaagttgga ctttagatat acaaactatc
    32101 ataacaaaag atataagtat ggaaaagcaa actaagatag cacaatatat atcattaggt
    32161 gtaggtatac tttctatagc tgttgcaata gtattagcaa atggagaaat aaagtcagca
    32221 tatgaatggt ttaatagttt tatggggcta gtactaggtg ttttagcagg aatatttgta
    32281 cttggtgcat tttgtaaaaa agcgactaaa atgggagcat atgttggatt catagtatca
    32341 gcaattttag ttgtttattt aaaataccgt atgccagaag taacttcttg ggcatattct
    32401 ctaataacaa tcacgacttc tgtagtggta ggtacaatag ttagtgcaat agaagctaaa
    32461 gttaaagcaa aagtatcttt accaaaagct gagactactg tttattatga aaaataatat
    32521 ttaaatgata aattgtctta tagagtgatt agataaataa tttagttact ctataagatt
    32581 gtataatata ctttgtatat aaaagtataa aaatagactt tataattata tagggagata
    32641 gtgcttatga tatttggaaa tataaatcat agtaagacat attcaacatt gcatgaagat
    32701 ttacttagat gttttgaata tgctaaagat aattcattaa tagattatga aaaaggtact
    32761 tatacaatag atggtgatga tatttttgtg aatattgtag agtataaaac ttgtgaaaaa
    32821 gaagatagat tctgggaagc tcataagaag tatatagatg ttcatttgat gcttgatgga
    32881 tgtgaacgaa tagatataaa ttttatagaa aatttagaac aaaaaatata tgaagaaaag
    32941 ggcgatttct tgcctcttga tggtaaaaat aatggataca tggaacttag aaaaggtgat
    33001 tttttagttt gttatccgga agatgctcat atgacaggaa taaaagtttt agaaaaagaa
    33061 aatatcaaaa aagctatttt taaggttttg gttagataat gataatttat ataaccacta
    33121 gggctgaaaa tagtgattta actttcagcg attagtgaga cttcgtaaat tttagttaga
    33181 ttactatttt cagccttagt tttttatgag aaaattgaaa ataattaaaa gcttaaaatt
    33241 ttgtaaagga gttaacttat ggaaaatata gatgtattct tattaatagg acaaagcaat
    33301 gctagaggat tgggaaatcc aaaagagagc atcattccaa atgaaaattg ttttgaatat
    33361 ttgagtactg atgaaattat aaatatgaga tgtgagctag agacttcaga aggtgatggt
    33421 actatagcac ctgcattttc aaatgaatgg aataagctta ctggaaataa agtttgtttt
    33481 attcacaatg caaaagatgg ttcaagaata aaaaactgga atcatgataa taactggttt
    33541 ctaaatgaca ctatagaaaa atttaataca ggctgtacta ccttaagtaa acattataat
    33601 atagaaaata aatacgttat ttggattcaa ggtgaaagtg atgcaaaata tggtagtgat
    33661 gtattgtact ataaagaaag tctaaaaaaa attgcgtata ggcttaaaga agaatgtatg
    33721 attgataaaa tgtttgtaag tttaactggt tattggcttg gagaagatga atattttatt
    33781 agaacaagac gaattgcagc agcacaggag tcggcttgta gtgaatgtga tatattatgt
    33841 gtaggaagca aaattgctat gcagtttcat gacagaggat taactattga tgatgttcat
    33901 tacactcaag aaggtcttaa tatgttagga gaggacttat gtaaaaatat ttataagtat
    33961 catataacca aagaaaaaag tgtattaagt gatactatag acttatcaga agcaaggaaa
    34021 tatatctgtg aattggaaaa gataagtaaa agatttgtgt aatataaaat tttaaataga
    34081 gttgttaatt tataaaaata atttgtatgg agatatgtta tgaaaaatta cgtttgtata
    34141 gatgttgggg gtacttcaat aaaatatggt tttattagag aagatggatt tataattgat
    34201 aaatcaagtc ttgatactga agcaaaggaa aaaggtggag aaggaatatt agccaaaata
    34261 aaagatatag taaaaaaata tatagaggaa aatgaaataa gtggtatatg tatatcaact
    34321 gcaggtatgg ttgacccagt tgaaggtaaa atactatttg cattagaaga attaattcca
    34381 aactataagg gcatgcaatt aaaaaaagaa gtagaaaaag agtttaatat aaaatgtgaa
    34441 gttgaaaatg atgttaattg tgctggactt ggtgaaatgt ggcttggagc aggtagaggt
    34501 gcaacatctt ctatatgttt aacaataggt actggaattg gtggatgtat tataataaat
    34561 aataaactga taaatgggtt tagtaatagt gctggtgaag taggatatat gaatgtaaat
    34621 ggaagttctt ttcaagaatt ggcatctact agcagtctaa ttaaaaaagt agcaaaaata
    34681 aaaaatttga atgaaaatga cttaaatgga aaaataattt ttgatttagc aaagaataat
    34741 gatgaagatt gtttaaaaga actcgataat atgataaaat cattagcagt tggaatcgca
    34801 aatatatgtt atgtaataaa tccagaagtg gtaattttag gtggtgggat tatggcacaa
    34861 gaaaagttcc taaaaccaaa aatagacaaa gcattaaagg aggttcttat agagagagtt
    34921 tacaaaaaca ctaatataga atttgcaaag agacaaaatg atgcaggaat gcttggagca
    34981 ttatataatt ttttaaacaa aatataaaga atagaagggt ttttaatgag tattttagaa
    35041 caattggaat caccaacttt taaagtcaca aaatcagata aattattaat agcttatata
    35101 aaagaaaata tagatgatgt attttataaa ccaatatcac aaatagctaa agagagcaat
    35161 attggtgaag caactataac taggtttgta aaaaaaatga attttaatgg attacaggat
    35221 tttaaagtta ctttagcaca agaaatatca actatcaata aaaaaaatat tataaataaa
    35281 aatatacaaa atgatgagcc agctttggat acagcaaaaa aacttttaag ttcaaatgta
    35341 accactttag agaacacagt agagataatc aatagtaagg atgtacatga ctgcgcaagg
    35401 cttataataa atgcaaagaa agtttacttc ataggtattg gatattctgg tataatagca
    35461 caggattcaa actataaatt tatgagaata ggtcttaatt gtgtaagttt tgacagtagt
    35521 catacaatga taatgatgtc ttccataatg gaagaaggag atttaataat tgcaatttca
    35581 cattctggtg aaacagaaga gattataaaa actgtaaagc ttgcaagagc caataatgct
    35641 aaaattatat caattactga aaataaaaat tctgaattaa aggatatttc agatgtacac
    35701 ttatcttatg tatcgggaga aacagtactg gaaaccggtt caatatcttc taaattagca
    35761 caatttttca ttattgattt agtatataca caggtagtaa aagaactttc taatgaagct
    35821 attgaaagga aaattaaaac tacaaatgct ataaaattgt ttaaaaatga ataaaataag
    35881 aaatttgtaa tgttttatag agctctctta aaaatttagg aatggagaga tattacatgt
    35941 ctaaattaaa agattataat attgataaag taataatttt taataattta agtactaaaa
    36001 cgaagaatca acttaaagaa aaagttaaac taaaaagatt acaaaaaaaa gaaattttat
    36061 tttatgaaaa agatagctta gacagtgttt atatactttt agaaggaaag gtatctattt
    36121 ttaagataag tgaaaatgga gagagaaaag taattttcat attaaatagt ggggaagtca
    36181 taaatgatat tacacttgac gcttctaaaa actctactgt tggctgtgaa gcatttgaaa
    36241 attcaattgt agcttattat agtattgaag aatttttaga acttatgcaa aatgattttc
    36301 aacttacaaa ggatattatt tcttatatgg aaagaagaat aagacgttta tatagacagt
    36361 tgaaaaattc tatatccata aaagtagata aaaaacttgc agcaaaatta tataggttaa
    36421 gtagagaatt tggagtttgc tgtggagaat ggactttact aaatgtaaat attacagtta
    36481 catatttagc tgatatgctt ggctgtaaaa gggagactgt ttccagaatg ataaaggtat
    36541 tgcaaaaaga agaacttatt aaaattgaca ataaaggttt ttatgttaaa gaaattgaat
    36601 tatcaaggta ttttaa
//
LOCUS       DAEOTL010000038        36484 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEOTL010000038 DAEOTL010000000
VERSION     DAEOTL010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36484
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.038"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..2476)
                     /locus_tag="KRH82_002156"
     CDS             complement(<1..2476)
                     /locus_tag="KRH82_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBG8655435.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQTT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLILGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVEPEVAYVVTDMLESVITEGTGGVAALPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGD"
     gene            2690..3388
                     /gene="yunB"
                     /locus_tag="KRH82_002157"
     CDS             2690..3388
                     /gene="yunB"
                     /locus_tag="KRH82_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBG8655436.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(3600..4607)
                     /locus_tag="KRH82_002158"
     CDS             complement(3600..4607)
                     /locus_tag="KRH82_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBG8655437.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            4835..5719
                     /locus_tag="KRH82_002159"
     CDS             4835..5719
                     /locus_tag="KRH82_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8655438.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            5921..7471
                     /locus_tag="KRH82_002160"
     CDS             5921..7471
                     /locus_tag="KRH82_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBG8655439.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETEDLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            7500..8147
                     /locus_tag="KRH82_002161"
     CDS             7500..8147
                     /locus_tag="KRH82_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBG8655440.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(8289..8549)
                     /locus_tag="KRH82_002162"
     CDS             complement(8289..8549)
                     /locus_tag="KRH82_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBG8655441.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            8766..10049
                     /gene="hflX"
                     /locus_tag="KRH82_002163"
     CDS             8766..10049
                     /gene="hflX"
                     /locus_tag="KRH82_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBG8655442.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            10057..10734
                     /locus_tag="KRH82_002164"
     CDS             10057..10734
                     /locus_tag="KRH82_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBG8655443.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            10820..11263
                     /locus_tag="KRH82_002165"
     CDS             10820..11263
                     /locus_tag="KRH82_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBG8655444.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            11568..12212
                     /locus_tag="KRH82_002166"
     CDS             11568..12212
                     /locus_tag="KRH82_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBG8655445.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(12298..12675)
                     /locus_tag="KRH82_002167"
     CDS             complement(12298..12675)
                     /locus_tag="KRH82_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBG8655446.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(12675..13061)
                     /locus_tag="KRH82_002168"
     CDS             complement(12675..13061)
                     /locus_tag="KRH82_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBG8655447.1"
                     /translation="MKKTDDLKQKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            13240..13995
                     /gene="nadE"
                     /locus_tag="KRH82_002169"
     CDS             13240..13995
                     /gene="nadE"
                     /locus_tag="KRH82_002169"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBG8655448.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            14078..14797
                     /locus_tag="KRH82_002170"
     CDS             14078..14797
                     /locus_tag="KRH82_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBG8655449.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(14964..15968)
                     /locus_tag="KRH82_002171"
     CDS             complement(14964..15968)
                     /locus_tag="KRH82_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBG8655450.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            16235..17131
                     /locus_tag="KRH82_002172"
     CDS             16235..17131
                     /locus_tag="KRH82_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBG8655451.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHINIKSDSCNC"
     gene            17269..18531
                     /locus_tag="KRH82_002173"
     CDS             17269..18531
                     /locus_tag="KRH82_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655452.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            18607..19800
                     /locus_tag="KRH82_002174"
     CDS             18607..19800
                     /locus_tag="KRH82_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBG8655453.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            20429..21223
                     /locus_tag="KRH82_002175"
     CDS             20429..21223
                     /locus_tag="KRH82_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBG8655454.1"
                     /translation="MESVMENLNNLKVELKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            21318..22658
                     /locus_tag="KRH82_002176"
     CDS             21318..22658
                     /locus_tag="KRH82_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBG8655455.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            22795..24027
                     /locus_tag="KRH82_002177"
     CDS             22795..24027
                     /locus_tag="KRH82_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBG8655456.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELISILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            24067..25209
                     /locus_tag="KRH82_002178"
     CDS             24067..25209
                     /locus_tag="KRH82_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBG8655457.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            25220..26014
                     /locus_tag="KRH82_002179"
     CDS             25220..26014
                     /locus_tag="KRH82_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBG8655458.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            26025..27047
                     /locus_tag="KRH82_002180"
     CDS             26025..27047
                     /locus_tag="KRH82_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBG8655459.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            27146..28522
                     /locus_tag="KRH82_002181"
     CDS             27146..28522
                     /locus_tag="KRH82_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBG8655460.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(28854..29198)
                     /locus_tag="KRH82_002182"
     CDS             complement(28854..29198)
                     /locus_tag="KRH82_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655461.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            29686..30696
                     /locus_tag="KRH82_002183"
     CDS             29686..30696
                     /locus_tag="KRH82_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBG8655462.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            30832..31320
                     /locus_tag="KRH82_002184"
     CDS             30832..31320
                     /locus_tag="KRH82_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8655463.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            31496..33424
                     /locus_tag="KRH82_002185"
     CDS             31496..33424
                     /locus_tag="KRH82_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8655464.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALEEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            33601..34011
                     /locus_tag="KRH82_002186"
     CDS             33601..34011
                     /locus_tag="KRH82_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBG8655465.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            34033..34335
                     /locus_tag="KRH82_002187"
     CDS             34033..34335
                     /locus_tag="KRH82_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBG8655466.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(34552..35244)
                     /locus_tag="KRH82_002188"
     CDS             complement(34552..35244)
                     /locus_tag="KRH82_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBG8655467.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(35270..36457)
                     /locus_tag="KRH82_002189"
     CDS             complement(35270..36457)
                     /locus_tag="KRH82_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655468.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
BASE COUNT        13666 a         4353 c         6551 g        11914 t
ORIGIN      
        1 tatcacctgt gttattattg ttattattat tttcttctgg ttggttattg tctggttttt
       61 ttgtatcttc agatgatggt tgagaactta ctttagtagg agcagtacct tcaataaatg
      121 ctgctttaga gccagaagat tgctttcctc catcctctaa attaattttt gtaaaatata
      181 catttttagg aacttcaaat tcagtaaccg ttaaattagc atgtattttt tccataattt
      241 tttcccataa ttttgcagtg ctagtacttc catgtggtac ttctctacgt tttatagtgt
      301 taccagaatc atcttttcta ccagcatcat ctccaatata agttgcacca acataataag
      361 gagtgtaacc gacaaaccaa gcatcatatg cactatttgt agtacctgtt ttacctgcta
      421 caggcattcc ctttggaagt gcagcaacac caccagtacc ttcagtaatt acactttcta
      481 acatatctgt aacgacataa gctacttcag gttctacaac tttatgttcc tcaggagcat
      541 ttttaactaa taattgacca tcaaaggtag ttatagtagt aaaaatagaa ggttctacat
      601 aaataccgtg atttgccaat gtaccataag cagcagccat ttgaagtgga gtaataccat
      661 tcgccatacc acctagtatc aatgatggga attttctatc acttgcttca gatgaacctg
      721 agtgattatt ctttaaagtt gttataccaa agttctttaa gtaatccatc attatatcta
      781 cacattcatc ataagagtct ccaagcattt cagcagtttt gacagctatc gtgtttgaag
      841 atttagcaag tgctttacgt aaactcatag aaccatgacc agcagtagta gttcttggat
      901 tccatttatt attttcttca aacttatatc ctcctcgaga atcacttaga gcagttgttt
      961 gtgttatttt tagagtatca atagctggcg tatatattgc taaaggtttt atagaagaac
     1021 ctggctgatg agggttagta gcacgattta aagtttttct accacttata tttcttcctc
     1081 cagctagtgc tcttatttca ccatttttat aatctaagat taccattgca gcttgcggtt
     1141 ggctaactcc atcaggacca accatatgtc ctgggaaatt gctatttcta tcaaattctt
     1201 cttctaaagc atcttgcatt ttagggtcta tagttgtgtt tacaattaga ccaccattgt
     1261 agaataagtt ttgagcttca tcatttgtat gtccttgttc cattaaagca tttataactt
     1321 cactttcgat aaggtcttct acagatgaag aaactttatc tgatgattga ggcaatttta
     1381 tttctatttt agctttgatt gcttcatcat attcactttg ttttatatat ttcaattcta
     1441 acattttctt taaaacaatt tcttgtcttt ttttagcttc aggattactt acagcctttc
     1501 taacaactaa tgtacctgct tttaattgtc tataagtatc attagatata agctcccaag
     1561 attttatttt ttcaatcata tcaaagtcca cttgagtagg gtcatctaaa tcatcatcag
     1621 ttgtgttaac aaaaaataat aatttattct ctaaatcctc cttagtttca tttccctcta
     1681 acttagaagt tttataggct gaaaatcttg atggattttt agttgaacca gcaagaagtg
     1741 ctgactctgc tagagtaagg tcagctgcag acttatcaaa ataaccacgt gcaccagcct
     1801 cagcacctgc tagacctcta ccaacgaaga agttatttaa ataagtttct agtattttat
     1861 ctttacttac tgttttactc atctcatgtg catagtaaat atcctttatt ttacgaggta
     1921 tagtttgctg ttcagttgtt aacagcattt tggatacctg cataggaata gtactaccac
     1981 cttgcttagt acctgtaagg gtctttaata ctgacctaaa taaaccttta atatcgacac
     2041 ccttatgctc ataaaaacgc tcatcttcta ttgcaattac agcatgttga agataagggg
     2101 aaatcttatc taatggaacg ggtgtctttt tatttacact tggagctgta gataatgttt
     2161 ttccattagc gtatttaata gtagttgttt ggttcgtctg tttatctaaa acagcttctg
     2221 taactggagt tacatctctt agtgacgcaa atactagacc agcagtacct gctgtaccaa
     2281 caactagtaa aactaaaaat actatcccaa atactcttag ttttttaaat ttatcgcttt
     2341 ttttagattt tttcttgttt tttgttgaac gagtcttgtt agctgaagtt ctattaattg
     2401 gtttatttgt attaccagat gagctaactt tttttctcct gattttattt ccatttttat
     2461 cattatcgtt attcataaga ttttaacctc cttacttaat gcaatattat aacacaaata
     2521 ggagtagttt tgtaattaat agaaaaaatg aatttgctat aatattctgt acattgtata
     2581 tgtataaacg taatatatta aaaagtctat atttttattt tatttatttt tgacaaatat
     2641 tataaaaatt atgccaaagc tacatataaa taaataggag gggataattt tgaatagaat
     2701 agtagataga aaaacaaaaa atgaatttag aaaaatcata gctatttttt tagtaattct
     2761 tttcttgtct gtatttatag gcagttttat atatatagat aaaactttaa gaccaacaat
     2821 aacagtttta gcagagacta aagctcttga actagcaaat aggtcgataa ataaagctgt
     2881 tgctgaaatg gtagaaggaa aaataaatta tgaagattta atggatatac aacttgataa
     2941 taatggtaaa ataactatga tacaagcaaa cactataatg atgaatgaaa ttgcatctgc
     3001 aatagcttta gaaatacaag atgaattaaa aaaggataag acagcaagtt cttacatacc
     3061 tataggaaca gcattaggaa gtcctatatt agctaaatac ggtcctaaac ttgaagtatc
     3121 tattgaacct ataggaacag tatcagtaaa ctttaaaacg gaatttgagt cttcaggtat
     3181 aaatcaaact agacatagaa tatatttaga agctcaaaca caagttaaag tagtaatacc
     3241 acttataact tcaacaaaac aaattaaagc tcaaatacct atttgtgaaa ctataatagt
     3301 aggtgatgtt ccagaaagtt atgtaaatat tccagaaaaa aatctaggaa atgttttacc
     3361 taacactgga aagaatacca acaagtaata taaagttgta tatttttaaa taaattcaaa
     3421 ataatagttt ataaataaaa tttttggaaa taatattaat ataattttaa taaaaattta
     3481 tattttatac tatgtaaaat atctaatata tttggtctgt aggttaaata aaagtacctt
     3541 tagaccaaat atattattaa taacttaata acatcttaaa acttatttat ttatattatt
     3601 tacaacatcc atttaataaa tacaccataa cctacagctg ggtcgttttc aattgcatgt
     3661 gacactgctc cgattatttt attatcttga actattggag taccactcat accttgtaca
     3721 ataccaccag tttgagctaa aagcttttta tctgtaattt taattttaaa acttttactt
     3781 tctggatgtt tttggttttc tatatctata atttcaatat tatatttttt acacttatta
     3841 aagttatctt gtaaaattat ttgagctttt cctaatttaa cttcatctaa agatgctact
     3901 ttatattttt ttaacttgga aatatcaaag ttattaattt gacctcttat tccaaaatca
     3961 gtattttctg taaagctacc aataatattt tctcgttttg catttataca tccaacacta
     4021 cctttataag atttttctat attaaggtgc ttagttgtag aaattgaacc tgttttaata
     4081 ggtatttttc ttgcattacc aacacttatt ggatgaccta cagctccaaa ctctgatgta
     4141 tctggattga tatacgttaa agtagcaaat ccagaaagta aattgttaaa actaattttt
     4201 tctaatatgt gtttggtagt tttcattgtt ataagttgtc cacctctatt taataaaata
     4261 gatacttgtt tttcttctgg taaagcattt aaggtattgg caaagtcact atatccatca
     4321 acttcagcat tatttacctt tactatagca tcacctaatc taaatggaga tgcttctcca
     4381 ggatttctaa ctatgatatt ttttaattct gcgtcaattt gaagtacgtt tccaattggt
     4441 attaaatatt caggttcatt tttttgtaaa ttttgtgcat aaattaaatt atttgagaaa
     4501 aaatataata aaaataaaaa tgttaaaaca attgtaaatt ttgacttagc taagttggtt
     4561 tttttactta aagtattatt tttaaaatga aaatttttaa gttgcataaa acacctcttt
     4621 cttattaaat tattttaata atagaattga agttttcttg ctgcttctat attatgttgt
     4681 gcaagaatca tgttttgatg cttggaaaac tagctcaata acaccttagt tttcataaaa
     4741 ataaataaaa taaatagtgt atatgataaa ataaatacat attcatataa ataaaaataa
     4801 acaataactg tctagcataa gaaaggagca aaaaatgaaa aaatatagat tgttagttac
     4861 ttgtataatt gccatgggaa tcataattat aggaacatca aatccagtta gcaattttta
     4921 caagactaca aatttgatta gttcaggaaa tatcacaaat gaaaaagcag ataaagatga
     4981 aaattcaaac aaaaataata aagataaaaa tgaagacaaa tctaattcta aaagtaataa
     5041 agataagtca tcagaggaca aatcgtcaga taataaaaat gaaattcaaa aaaacaaaaa
     5101 acttttaatt tgtatagacc cagggcatca aggaaaagga gatagcaatt tagaaccagt
     5161 agctccaggt tcttcctcta aaaaagcaag agtatcttca ggaacagagg gtattgctac
     5221 aaaaaagcca gaatatgttt taaacttaga agcatctctt gttttaaaga gtatattaga
     5281 atctaaaggt tataatgtaa taatgactag agagacacat gatgtaaata taagtaattc
     5341 agaaagagca atacttgcta atgacaaaaa agcagatatg gttgtaagaa tacatgcaga
     5401 tagtttaaat aattcttcaa aaactggagc atctatattg attcctgaaa aagatggaaa
     5461 atatacagct cctatatatg aagaaagtaa taaatgtgct gaatttatca aacagaatat
     5521 ggaacaatca ggtatacaaa tcaatggaat cgttcaaaga ggtgatttga ctggattcaa
     5581 ctggtcaaaa gtaccagctg tattagtaga aatgggattt atgagtaact ataatgaaga
     5641 ccaaatgatg tcaaatccag actaccaaag aaaaatgatg cagtgtatag ctgatggatt
     5701 ggatgcgtat tttaaataag atatgaatag agaaaaagtt aggttggtat tattttccta
     5761 atttttatct ctatttttta ttgtacataa cacaaagaag aagtttattt taggttaaat
     5821 tgtcgtaaat ataactaaaa atattgggaa tacttgattt aagtttaaaa agaatatatt
     5881 atagtataga atgtgtaaaa tttttttgag aggtgttgaa atgctagtag tagaaaatgt
     5941 gagtcatgga tttggtgcga gaacaatatt agaaaatgta tcctttagac ttagaaaagg
     6001 tgaacatatt gcactagttg gtgctaatgg agaaggaaaa tcgagttttt taaatataat
     6061 aacaaagaag cttatgccag atgctggaaa tataaaatgg tcttcaagag ctacagtagg
     6121 ttacttagac caacatacgg tattaagcaa gggaaaaact ataagagaag tgcttagaga
     6181 ggcttttaag catatgtttg acttagagca agaaatgatt gctatgtatg acaaaatggg
     6241 agaagctagt gatgatgaaa tgagtaagct tcttgaagaa acagcagaga tacaaactat
     6301 acttgaaaat agtggttttt atatgataga tgcaaagata caagaagttg caaatggtct
     6361 tggtcttgga gaaattggtc ttgataaaga tgtaactgac ttaagtggag ggcaaagaac
     6421 aaaagtactt cttactaaac ttctacttga aaatccaact attcttatat tggatgagcc
     6481 tacaaactat ttagacgaag agcatataac atggcttact aagtatcttc aagagtatga
     6541 gaatagtttt gtcttagttt ctcatgatat tgaatttata aataatacat gtaatgtaat
     6601 atatcatatg gaaaatggag agttaaatag atataaagga aattatgatg aatttgtaag
     6661 acttaatgat ataaagaaac gtcaagaaga acaagcttat gataaacaag ttgaagaaag
     6721 aaaaagacta gaggattttg tagctagaaa taaagctaga gtagcaacta gaggaatggc
     6781 taacagtaga caaaagcaac ttgataagat ggaaatatta gaaagaccaa aagaaaaaat
     6841 aaaacctact tttgctttta aagatgctag agcagctagt aaaataattt ttgaaacaga
     6901 agatttagtt ttagggtatg atgaagcatt gacaaaacca cttaatttcc atttagaaag
     6961 aggaaaaaag attgccttaa aaggaatgaa tggtattgga aaatctactc tattaaaaac
     7021 tttacttgga ataataaaac catttgaagg aaatgttaaa ttaggtgact atttggaagt
     7081 tggatatttt gaacaagaga gttcaagaga aaatagtaat acacctatgg atgaagtttg
     7141 gagtgaattt ccagggctta caaactttga agttagacag gctcttgcaa aatgtggact
     7201 tacaaatgaa catataacga gtcaaatgag agtattaagt ggtggagaag ctgctaaggt
     7261 tagactttgc aaagtaatgt taaaaaatat aaatttctta gtattagatg agcctacaaa
     7321 tcatttagat gttgaggcaa aagatgaatt gaagaaggct atcaaagagt ttaagggaac
     7381 agttctttta gtatgtcatg agccagaatt ttattcagaa attgttgatg atgtatggaa
     7441 tatagaagat tttacaacta aaatcgtgta gtgatttaac ttattgctgg ggggatttca
     7501 tgaaaaagtt tctaaatgta cttttttcaa tttgtattag tattgttata atagtaggtg
     7561 ttattaattt tactgttgga tttaaacaac tttattattt tgacattgat tacttaaata
     7621 tatcagagtt atctggttta tctaaagatg atataaaatt gaactacgat tatctaattg
     7681 attataactt aaataagaat gtgtctgagt tcaaattacc aacattaaaa tcttctccac
     7741 aagggaagat acattttgaa gaagtcagga atatatttca aaatataaat aaattagcta
     7801 aattattatt ggtagtttct ttagtaggaa ttatattgag tgtaaaaaat aaaaatataa
     7861 aaatcttaaa aactacatca ataacactta taattatgcc attattatta acagttccaa
     7921 ttttattaaa ttttgaaaag tcatttatta tttttcataa attattattt agaaatgatt
     7981 attggatatt taatcccgat ttagacccag ttataaatat attgccagag gaattttttt
     8041 ttcactctgg aatgatgatt ttaatattaa ttttgttagt aagtatagta ctgtttgtaa
     8101 tgtataaatt atgtaaatct ttatcaataa aaatatttca atgttaaata gagggatatt
     8161 tttatttcca aaataagata ataaaaaagg attagattaa aagttataca ataaaaatag
     8221 ctgtgcaata atatttagac tatgaaagta gttaaaaaat atttatgcac agctatttat
     8281 aatagaattt actttttact agtgatttta actaaatctt gaaatttact cataatgtaa
     8341 ttgtaattat cttttttatg aggtaatata caactactgc aatctttgat acctttatct
     8401 gtatacttaa agtttccacc acagttttct cctaaagcat acaaaggaca atagcaaaat
     8461 agacagttaa actcttctgg tttattagtt ttatgacaag ggaaaaattc gcaatctttg
     8521 tgattaaaaa acttataatt ttcgcccata ttttcctcct aattaaataa aatttaaatt
     8581 ttttatacta tataagattt tggtgataat ataattatac taaataattt tatgaatagt
     8641 cgataatata gtattattaa tcatagtatt aatggtataa ttagtcaaca gaaaaataat
     8701 gtaaaaataa tgtaagtgta ttttgtaatt agaatatgtt ttataacaaa aaatgaggtg
     8761 attaagtgaa agaaattcaa gaaaaagcac ttcttgtagg tctgaatttg actacaatag
     8821 tgaaaaaaaa tgatgatata gacactaatg aatctatgga agaattaaaa gaactaacaa
     8881 aagctgctgg ggcagaagtt gtaggtagct taattcaaaa taaacactct gtagatgcag
     8941 cttattatat aggaaaaggt aaagtagaag aaataagagc ctatagtgac tctttagatg
     9001 ctactttagt aatttttaat gatgaattat ctggtgctca aatcagaaat atagagaatg
     9061 ttgttggaag aaaagtaata gatagaacta ctttaatttt agatatattt gctcaaaggg
     9121 cacttagcaa agaaggtaaa ttacaagttg aattagcaca attaaaatat agattgccac
     9181 gactttatgg aatgggtggt gagatgagta gaacaggtgc agggattggt actagaggtc
     9241 ctggagaaca aaaactagaa atagataaga gacatatact taataaagca gcagatataa
     9301 gacgtgaact taaagaagta aaaaagaata gagagacaca gagagttaag cgtttaaagt
     9361 caaatatacc gattgtagca cttgttgggt atacaaatgc aggaaaatct accctgttga
     9421 acgaattaat aaagacacac aaggattatg aacaagaaaa agaagttttt gtaaaagata
     9481 tgctttttgc aactttagat gtaaccttga gaaaggctct tttgccgaat aaaaaagaat
     9541 ttttagtagt agatactgtt ggatttgtaa gtaaacttcc ccatgattta gtagaagcgt
     9601 ttaaggcaac attggaagaa gtacagtatg cagatttaat cttacatgta attgatgcaa
     9661 caaatactag ttatgaattg caaaaaagta cgactgaagg tgtattaaaa gaacttggtg
     9721 taaatgataa aaaacatata cttgtatata ataaagtgga caagctagaa ttggatatat
     9781 accctaaaag tcaagaagat attgtgtata tttctgcaaa acaaggcata aatatggata
     9841 agttattaaa tatgatagaa attgctttaa tggaaaatac ttattcagta agtttgatgt
     9901 taccttatga gagaggtgat atatttagta gaataaaaga taaatataat gtggagaatt
     9961 ttgagtatgg ggaaagtggt ataacgctag atgtagattt agatgaagaa gattttaata
    10021 tctatagaga gtacatacta gaaaaatagg ttgaatatgg atataaactg ggaaaatata
    10081 gataatcttg aagattattt tataacctat cttctttata aagaatctaa aacagtatct
    10141 caaattagta aaattagaaa tatttcaagt actgaagcaa gtgagcaact tatacaagca
    10201 aagttaaaaa taaaggaaat gcaaaaagat gattttgagg catctaagga tattttggat
    10261 aaatttctag aactagataa aattaagaga cttgatttta tggatagctt agatgacgaa
    10321 aaaatggtat actttaagag aaaggttttc aaaagaatcc ttgtagaaaa aaatgctgaa
    10381 gatttaattg ttttaatttg ggcgacaggt gagctaaaag atgataggtt tttgaaattg
    10441 cttcatcagc tcacaaacca cagacactca gatattagaa gaataactta ttcagcaatc
    10501 agaaagattg aatcaccaag tagtagagaa gtactgcaaa aaggtctcta cgacaaaaat
    10561 gcacagacta ggcagtactg tgcaaaagct ctttcaaaat tgggagatga aaacagttta
    10621 aagattttac agcagttgaa agacaagaat aagaattttg aaaaagaata tgtgcttaga
    10681 gcttatgacg aagccattaa gtcattggaa aatgcaaaaa atttgaaaaa gtaatttttt
    10741 attaaagcaa tttgtttgct taatgatgta tttctaaagt ttaacaaggt aataaataaa
    10801 ttaatgggag gggtttcaaa tgatagtaag acgttgtgca ggtggagtag tgttttatgc
    10861 taataaagta cttattgtaa aaaatgatag gggtgaatgg acacttccaa aaggaaagat
    10921 actaggaggg ggacttccat atgagagtgc tgttcaaaga gttaaagtag aaactggcat
    10981 agatgctaaa atgatagatg tggctggcga tactatgtat gaatttttct caagaagtag
    11041 acaacaagaa gtttgtaatg caataatgtg gtatgttatg gaagcttgta acactgattg
    11101 tgtacttgct cctgaatttc aagaaggtgg attttataaa gtaaaggatg ctttagaaat
    11161 gttatcacat cataaagagc aagctttagt agaagtatct tataaaaagt ttaaggaatt
    11221 aaagaaatta gtttcagagg gcgatgatgt tccagcaaat taattgtgaa tttagaggat
    11281 tctgaggaag ggatagcccc ttcctttttt aattgaagca gttttaagcg taaattatat
    11341 agtctcttta aactatgatt tatcaattta gagatttagt agtttatatt taaaatcagt
    11401 aagatatatt taaaataaaa attaaaaagt atacaatttt attatataat tgtcttatga
    11461 tgttgattaa agaattatta aaagtccatt tatttttaaa tagaataatt ttataaatat
    11521 atatttgatg tgtatattag aaaatgatta aaataggagg aaatacaatg agcaattaca
    11581 ggacattaca tgaatttgga acggatgaaa taacgattga aaagtctgtt tttattggat
    11641 atgctaagcc tataaagagt gaagaagaag cattagagtt tataaatgaa ataaagaaaa
    11701 agcataaaga tgcaactcac aatgtgtggg cttatactgt aggtaaaaat atgaatatac
    11761 aaagatatag tgatgatgga gaaccacaag gaacagctgg gatacctaca ttagaggtta
    11821 taaaaaaaga agatttgaga gatgtagcgg ttgttgttac taggtatttt ggaggaacaa
    11881 aattaggtgc aggtggtcta gttagagctt atacaaaagg tgctaaactg ggacttgaag
    11941 caggtaagat aatttataag gtaatgtatc aagaagttaa ggttaagata gattatactc
    12001 aacttggaaa agtgcaaaat gagttaatga atttggggta ttttataaaa gatactgtat
    12061 atgaggataa tgttgaaata gtagtatatt caagattaga agatgtagag aaattatcag
    12121 aaaaaatgat tgatataaca agtggaacag gaaaaatagt tttaggagag gaattttatt
    12181 tgtctgaaca aaatggagaa attttaatat aatctaaaag gttattagaa tagttaatac
    12241 ctcaaatagc caattagtat ttttaagtga aaagccatta aattgattta atctaaatca
    12301 atttaatggc tttttatcgg attttgcaca gaatcctttt tttacttcaa ataaaccgac
    12361 taaaagtaaa aatatcccaa atattttttt taatatatct gaagacagat aattagctaa
    12421 tagtgaacca aatacagctc ctaaaacccc aaacacagct ataggtataa ccaatttaaa
    12481 aattacattt ttatttttta tatgtatagc aagtgctata agtgtcatag ggatagatga
    12541 aagtaaattt acgctttgtg ctattttagt gtctatgcca gcaagtaaaa cgagtgcagg
    12601 tataaggatt gttcctccac ccattcccat tcctccaata attcctgcaa aaaatccaat
    12661 tagagcaaat aacattaaaa caccatcctt aatgctgcaa ttatcataat tattccaaaa
    12721 gaaattctaa gaaactttcc agtaacctta tttagtaatt tagctcctat aataccacca
    12781 agaatacttc caactgcaac tttaattgtt aagttaacat cataagtacc tttagataca
    12841 tataaaacag aacttgctgt cgttaagaat attattatag aaagagcagt tgcatgagat
    12901 ttatgttctt ctaccttaac gatgtcattt aatattggaa ctaaaagagt acctcctcca
    12961 gaaccaaaaa ctccatttat aaatcctgta aaaactccaa ttatcgtatt ttttaagtta
    13021 aaatcaaagt atttttgctt taaatcatca gtttttttca taaaaatcac cttctgaaat
    13081 agttttacca aaataggcaa attatattta tataaaataa gattaaatat aatctttcat
    13141 gtttgtttaa ttttgcataa aaaaaaacat attaaaacaa catattaata tatggtataa
    13201 tatattaaaa caaagtagca aatttgagag gagataacaa tgtcaaatat aaaaatacaa
    13261 atagacaaaa ctgtagaatg gcttataaat aaggttaatg aggcaaatgc aaaaggatta
    13321 attgttggtg tatctggagg aattgattcg gcagtagttg ctaatttaat taaaaaggca
    13381 tttccagaaa actctatggg agttataatg agcataaaaa gtaatcctca agatagagaa
    13441 gatgcactta aggttataga gggatgtgat atagaatacc ttgatttaga ccttatagaa
    13501 ccacaaagtg ctatattaga catggtagta ggaaatttaa aagataaaca tttatataga
    13561 gaagaatatt taaagatgac agatgcaaac ttaagagcaa gagtaagaat gagtacaatt
    13621 tatacaattg ctaacaatct aggatatctg gttgttggta cagacaatgc tgcagaaata
    13681 cacacaggat attttactaa atttggtgat ggtggagttg atattttacc tattgcaaat
    13741 ttaactaaag gagaggtgta tgaatgggca aaagagcttg gtgttcatga agatttaata
    13801 aacaaagctc cttcagcagg tctttgggaa ggtcaaacag atgaagatga aatgggaact
    13861 acttacaata tgatagatgc tgtattagaa ggtagattgg atgaagttcc taaaagagac
    13921 caagagataa ttgaaagact tcatagatta agtgaacaca agagaaaaac gcctgcacaa
    13981 cctcctaagt tctaatttac tatttataag atttgtgata aaatttacaa gtgatgaaaa
    14041 ttagaataat taattgtacg tattaaggag tggaaatatg ggacgtatag gtaatataat
    14101 taatagaaaa ggtaaacaag atgctcaaag agcaaagata tttactaaac atgctagagc
    14161 aatagcagtt gcagctaaag aaggtggagc agacccagag tacaatgcag cgttaaaaac
    14221 agctatagaa aaagctaagg cagataatat gccaaatgat aatatagata gagctatcgc
    14281 taaaggtgct ggagcaggtg ctggagaaga ctatgaaact atagtttatg aaggatatgg
    14341 acctggtgga gttgctgtta tagtagaaac tttaactgac aacaaaaaca gaactgctgg
    14401 taacgtaaga tactattttg acaaaaacgg aggaaactta ggaactagtg gatgtgtgtc
    14461 ttttatgttt gataaaaaag gacaaatatt agttggttta ggagatggag tttcagaaga
    14521 agaattgatg gatgttgcat tagaagcagg agctgaagat ttcataacag aagaagatgg
    14581 ttatgaaata ataactacac cagaagattt ttctagtgtt cgtgatgagt taaaagctaa
    14641 aggatatgag tttatatctg ctgatgtgaa gatgatacct caaactacaa ctgtattgac
    14701 tgaagaatct catttaaaaa tgatgaataa attagttgat atgcttgaag aagatgatga
    14761 tgttcaagat atatatcata actgggaagt agaataaata gtataagcat attgaaattt
    14821 ataagtattt aatcaatttt aacatgtgat aaattttata gaataagaaa cactaaaata
    14881 gacatacgca cctctaacct atatttgcat aataatatgt aagcataggt aaggggtgtt
    14941 tttatattta taggttaaga aatttaaagt aaattttgag ctggactcga ttgtctataa
    15001 ataattgatg ggtatataac ttgttgctga ataccattta tacgcccagt tactgtatca
    15061 ataatcatcc taagactacg ttctgctgtc tcttccattt ttaaatctat aactgtcaaa
    15121 ggaggaatac ttcttgccat tagtcgtgaa ggtccattac ttgctgcaaa tatttgaata
    15181 tcctctccaa ttacaattcc cgattcatga aatgcattca tcataccaag agctaccaca
    15241 tcatgattac aaaaaattac tttttttagt gaattttttg caagcatttt ttgagcaata
    15301 tcatatccac tatctatttt attagaacaa taatatatag aatctgatag atgtattcca
    15361 tgttctttac atgtttttaa aaaagattta ccccttaaag tcatacatgt aaaggaagtt
    15421 gggttgaata caacagcaat atcattttta ccattttgaa tagcatgtaa agctgctata
    15481 cgaccagttt cctcattatc aatagataca cttgaaaaac caggtatttc acgatttaca
    15541 acaactacag gaattttagg tttatttttt actagatatt ctatatcatc agcattgata
    15601 cctgttaaaa caattccatc ataataatta tttgcaaaaa agtattcatc atcacataga
    15661 tgaccaactt tgtaaggtcg tatgatgata tttatgttta aatgttctaa agaaattatg
    15721 tggtttattg cttgaagtat attggttgat gccaactcaa atccctcatc ctgccaataa
    15781 aaagctattt taatattatt atgtttaata ggagtagagc gtttatatcc aagcttatca
    15841 gctgaattta atataagctc ttgtgtatgt agcggaatcc tgcgttcatt tcctttacca
    15901 cttaagacgt acgagacagt tgctgaagaa agaccacagt cttttgcaat atctttgatt
    15961 gttgccatga taaaatcctc cttaaatagt tgcttaaatt tgcttatacc aataatctta
    16021 acatatattc aactaaagaa caatattcta caaggtgcat attttacagg attagaataa
    16081 ataaattaaa aaaaaacttc ttacttatgt tgacataatt tagtttatag gattataata
    16141 tgcttaaata agcttatgat taacttaaat taagcaaagt taagcaggaa catgcaatgc
    16201 tagcttgcaa tgtgactgta aagggggaaa aggtatgagt aaggtaaata tatttgaagt
    16261 tggtcctaga gatggatttc aaaacctgaa agagttttta gaaactgata aaaagcttaa
    16321 gattattgat ggtcttattg cttcagggat taaacaactt gaaattagtt catttgtaag
    16381 cccaaaagca atacctcaga tgaaagatgc aaaagaagta gcaacttatt gtgtagaaaa
    16441 atatcctgat gtgaaacttt atgcattagt tccaaattta tacggtgcta aagttgcatg
    16501 ggagtgtggt ataagagata tatcctatgt tatatctttg agtgaaactc ataataaaaa
    16561 aaatataaat cgtacccatg aagagtctat tgatgagctt aaaaaaataa tgaatactta
    16621 tccagacatg aatatatgta ttggaatggc tactgtattt ggatgtcctt ttgaaggttt
    16681 accaaaaatt gaagatgcca taagatttgc taaacgcctt tgggaaaacg gtatcaggga
    16741 gataaatcta gcagatacaa tagggattgc tgaccctaag caagtaagag aaactattag
    16801 tgcattagtt gaagctttac cagagtgcag atggcaagta catattcatg atactagaaa
    16861 tatgggaatg gttaatactc ttgtggctat tgaatctgga attactactg ttcagtctac
    16921 acttggagga ttaggaggat gcccatttgc tcctggagca tctggcaata ctgcaactga
    16981 agatttagta tatatgcttg aacgtatggg gtatgataca ggagttgatt ttgttaaact
    17041 tcttgaatta tcaaagtatc agaagagttt tgtaaatgga gtatatagtg gtcatcatat
    17101 aaatataaag tctgatagtt gtaattgtta gttctattga ttaatcgatt aaaaaaatat
    17161 gttgattaaa aaaatatgct gattggtaaa atagatttat tgataaaaaa tataaattat
    17221 aaaatacatt atctaataaa acaaataaaa aaattgaggg ggattagtat ggatattata
    17281 gctttacttt tatttttagg agttattatt attgcatttg tacgtaagaa taatgcaggt
    17341 attttggctc tagctattgg tgtcatagct gttagaattt ttggaatgga tgataaagaa
    17401 ctttatggag ctataagcaa ctcaatgttt actacacttg ttggtataac actactcttt
    17461 gcaatagtga actcaacagg agcattaaag cttgttgcag aaaaaattgt agctgcttct
    17521 ggtaaacgtg tttggcttat acctatagca gtttttatag caggatttgt tgttgctggt
    17581 gttggacctg gggcaattcc agcacttgca attatcccag caatggctgt tcctgtagcc
    17641 ataacagttg gttataatcc tgtaatgctt gcacttatag gtgaatgtgg attaatggca
    17701 ggtcgtatga ctcctattac tccagaaggt caaattataa caaccgttgc agaaggggtt
    17761 ggaattgaaa atgttatgcc tactatctta gcctgtcaaa ctctttctac aattgtattt
    17821 tcaatagtat tgtttataat tttcaaagga tataaactta aaaaacctat aaatgttata
    17881 gatagtaagc aaatagaaaa attcaatata aagcagataa tttctctaat aagcatagta
    17941 gttatgattg cttttatcat aatttttgat atgaatgttg ggcttgcagc ttttgcagtt
    18001 tcagctgtac ttattttttt caatattgct gatgaaggag aatgtatcaa atcaattcca
    18061 tggagcacga tagtaatggt tcttggagta ggtgcaatga tgacaatcgt agatgcagca
    18121 ggaggtattg acttgatgag taatgcatta tcatcactga tgaatagtaa aacagctact
    18181 ccaattatga gtatttcagc aggacttatg tctatggtta gttctgcttt agcagtagtt
    18241 tatccaacta tgatgcctat gtgtgttgat atagctaagg cagttggagg agtagaccca
    18301 ctagcactta ttgctgcagt tggtgttgga ggttctcttg ctggtgtaag cccactttct
    18361 actggtgggg cattgatttt agcagctatg ggttcaagta agaaagactt taataaggaa
    18421 gaacaaaata aggtttttgt acagcttttc attatgagtg cagttggctt attggttatt
    18481 gcagtagtat caatattatc atttaatgca ataacacatt taatgaacta attagaataa
    18541 ctgaaaataa atcattaaat ttaactttta atattaatca atataatata atttggaggg
    18601 gaagttatga aaaaaggagc attaagcaat ataaaggtac ttgaccttac aagagttctt
    18661 gcaggtccat attgtacaat gatgttggcg gattttggag ctgatgttat aaaaatagag
    18721 atgccaagaa aaggtgatga tacaagaggt tttggacctt ttgtaaatgg agagagttta
    18781 tactatgcaa atataaatag aaataaaaaa ggtatcactc taaaccttaa atcagaagaa
    18841 ggaaaaaata tatttttaga aatggtaaaa catgctgatg ttgtagtaga aaattacaga
    18901 ccaggtgtaa tggaaaagtt aggtctgggt tatgatgagt tggctaaagt taacaatcaa
    18961 ataatttatg gagctgtatc aggatttgga tgttatggac catattcaga acgtccaggt
    19021 tatgatatta ttgcacaggc aatgggtggt cttatgagta taacagggca agaaggagga
    19081 gaaccaacga gagttggtaa tgctatgggt gatgtactag gtggaatgaa tttaactatt
    19141 ggtatactca cagcactcaa cgctagaaaa ataataggaa aaggacaaag agtagatgtt
    19201 tccctcgttg attctgttgt atcgtctctc gaaactggta tacagagata ctttgattca
    19261 ggacaacctg aacttatggg taatagatat gcttcagcct atccttatga ctcttttaag
    19321 gcaagtgatg gaagttttgt aataggctgt ggtaatgaca aactttttga aaagttatgt
    19381 aaaaaagttc tttttagaga agacctttta atagatgaga gatttaaaac aaatcttaat
    19441 cgttgtgaac attacaaggc tcttaaacca gaaatagaaa aatggtctgt taagcataca
    19501 ataaaagaag cagttgactt aatatcagag gctggagttc ctgctgctcc tatctataat
    19561 cttgattgtg ttacaacaga tgaacatata gcaaaagcaa gagaaatgat tgtagatatt
    19621 agtcatccta ttataggaaa tatgaaagtc aatggaaatc cagttaagtt gatgacaaca
    19681 aaagctaaaa ttgatatgcc agcaccatct ctaggggaaa gtaacgagga gatttataat
    19741 ggttggcttg gttttgatag tgataaaata aaagatttaa aagaaaatgg agttatttga
    19801 ttaaaaaata gctaaacaca cttgtgactt tagtcatggg aggttcagtt agaataatat
    19861 caaaaaatat taaatcaata ctgtaaatca aatatagaat tgtcagaagc atttaagatg
    19921 ggaaaagcta cttagacatt gagtctttgt ggcttttcct attttcatta agaattttat
    19981 attatcagaa tagatatgta ctaaactaaa gtattaacaa tttaaattaa tagaaaataa
    20041 actacctaat tatgttgaat aaagactact ttagtgaaaa taaacttata gagatgctat
    20101 ttaaattatt ttaatggaaa tatcaaaaat gagactgcat tctcaaaaat gagactgcgt
    20161 tttttaagta ttttctcgaa aatgagacaa aaatattgtt ttatgggttt tattgaagaa
    20221 aaattcttct gtgaattaca atttaatcaa ttttaaagtt gaaaattatt aaaaatttag
    20281 tgaaatttat gtatatttcg tttattttat taaaaataac aattttttac taaaaataaa
    20341 gaacttcaat ggtgattggc atagtacttg ctattttata ttaacaagaa atgtagaaaa
    20401 aataacaatg tataatgggg ggaatatgat ggaatctgta atggaaaatt tgaacaatct
    20461 taaggtggag cttaaggaca aagtctgtgt tattactata aatagaccta aagctttaaa
    20521 tgctcttaat agtgacactc ttagggaact atcacaagtt attgatgtag tatcagaaaa
    20581 tgaggcaata ttaggagtta ttattactgg agaaggtaaa gtttttgtag ctggtgctga
    20641 tatacgccag atgcaaaact ataaaagtga ggaaggcaga aaatatgcag gttatgctca
    20701 gggaattttt gataaaattg aagctctgga gaaaacagta atagcagcag ttaatggata
    20761 tgcattaggt ggtggatgtg aacttgctat gagttgtgat attagaattg catcagaaaa
    20821 ggctatattt ggacaacctg aagttaattt aggagttatt ccatgttttg gtggaactca
    20881 aagattatca agacttgttg gaactggaat agctaaagag ttaattttta cggggagaca
    20941 agtaaatgca gaagaagcta aatctattgg gcttattaat aaagtggttc caagtgattt
    21001 acttttagaa gagtctatga agatgatgaa ccaaatagtt gaaaaagcgc caatagcaat
    21061 aagatatgca aaagttgtta ttaacaaagg gatagatatg gatttaaaga atgctcttga
    21121 actagagaaa gatattgcag gtttaacttt tgctacaaga gataagcaag aaggaatgaa
    21181 tgcatttata gaaaagagaa agccagtttt tgaaaataag tagctattat aactaaaatt
    21241 ggaacaatgt agaatatatt caaaatctaa atttcgtgaa aaaatacata tagtttaatt
    21301 ttaaaaggag ttaatttatg aatacgggag taattataag tttagtaggg attatcatag
    21361 ctctatctct tctagttgta atggttatga agggaataaa tatttttatt atagcaattg
    21421 tatgttcatc attagttgct ataacaggaa gcctaaatgt gtatgatgca cttaaagtgg
    21481 attatatgac agggtttgtt ggatttcttc aggcaaattt ctttattttc ctaacaggta
    21541 cattaatggg aaaaataatg gagattactg gtggagcaaa atctattgct aagatgattg
    21601 taagatggat tgggaaggat aaagcactac tttctattcc aatagcttgt ggaatattag
    21661 cctatggtgg agtaagtgtt ttcgttgtaa gttttgcagt gtttccgata gctttagaaa
    21721 tttttaaaga agctgatttg ccacgaagat ttataccagc agctttgact tttggatgct
    21781 caacttttgc tatggttgca ccaggggcac cacaaattca gaatattgtt ccagcatcaa
    21841 cattagggac agatattatg gctggagcag taaatggttt tatatcatgt gcagtaatgt
    21901 ttatagttgg aagtacaatt ttgtacaaaa tggtttcaaa agaaaaagcc aatggtggtc
    21961 attttatagc acatgagtca gatatatttg atgaagcaga agcaactaat tctaagagag
    22021 aaaatggtcc caatggtgta attgccttaa ttccattgat agtgtcaatt ttaataatta
    22081 atgtaaaagt taatggaaaa gcgatagtac caattgaggt gggagtattt attggagctt
    22141 tattagtata tttattgtta aataaatatc aagataatac taaaatagtt ggacatgttg
    22201 gtgatgcatg taaaactaca gtagtagcaa tatgtaatac ttgtgctgta gttgcatttg
    22261 gttcagtagt aaaatcagca gttggttttg acttcatagt taatgccatg actaatattc
    22321 ctggtcctcc tattgcaggg gctgcagttg gaactacagt tattgcaggt atttgtgggt
    22381 cagcttcagg tggactagga attgcagctc cacttcttgg accagtattt ttagccaagg
    22441 gtgtttccgc tgcagcatta actaggacta tggcaatttc atcagcagca ttagattcac
    22501 ttccacacaa tggatatatt gttactgtaa caaatggtct ttgtaaagaa acacataagg
    22561 atgcctatat gccaatattc tgggtaactg ttttaacccc atttattgga accatagtag
    22621 cagtcctact gtttacaatg ttcccgggat tgccataaga gaaaagataa aaggtataaa
    22681 ttatattttg atattataaa atcaattttc aaaatatata caataaattt catgttttaa
    22741 tactgtaaat atgtatttaa aataacaaat tgaccatata aggaggaatt gaaagtgtta
    22801 aataaaccat tagagggagt taaggttatt gacctaacgt attttgtagc aggtccaggg
    22861 acttctaaaa tattagctga ctggggtgct gacgttatta aggtagagcc aagctttgga
    22921 gacccaggaa gaaagacagg ggcaacaatg acaatgccaa tagatgatta taataatcct
    22981 ttttacagca catataattc aaataaaaga ggtttgtcta taaatcttaa gagtgaaact
    23041 ggaattgaaa ttatggataa gcttttaagc gaagcaaacg tatttgtttc aagttataga
    23101 acaggagcgt taaaaagact aggtcttgat tatgaatcat taagtaaaaa gcatccacac
    23161 cttatctggg gtcagataaa tggttttggc gattttggac ctgctaagga taatgcagga
    23221 tttgatacag ttgccttttg ggcaagaagt ggggctatgc ttgatatagc agaaaaagat
    23281 acaagtccaa taaatccacc tatagccttt ggagatgcaa caacttcttg tagtttatct
    23341 ggaggaatat gtgcagcttt gtaccagcaa gctaagactg gcaaaggaca aaaagtaatg
    23401 gcatctttat ttgggcaagc aatatggaat gcatcatctt tattagcatc tacacagttt
    23461 agtgatgagt atccaaaaac tagaaaaaat gctatttcac cagtaataaa ttcttatcgt
    23521 tgtaaggatg gaaagtggat attcttaagt attttagagc atgaaagata ttttgaggca
    23581 ctttgtagat tatttggaag agaagactta ataaaagaag agaaatttgc atcttcagta
    23641 gaaagtaaga aaaatgccac agaacttatt agtattttgg atggtgaatt tgcaaagttt
    23701 actcaaaatg agatggttga aaaacttact gctgctgata tagctcatga aaaaattcaa
    23761 catgttaatg atgtagtgac tgatgaacag gctattgcta ataactatat atatgaacat
    23821 acaagtaaaa atgggaataa gacaatgctt gcatctactc cagttaaatt tggaaatatt
    23881 gaagttaaca tgacttgtga tgctccactt ataggagaac attcagatga gatattgaga
    23941 gaacttggat acagtgattc tgatatagaa gctctaattg aatctggaat tgtaacaatg
    24001 aataaagaag catgtgaaat atgttaataa acatgtgaag tatgttaata aataggaggg
    24061 aattttatgg attttagatt aacagaagca caattaatgc ttcaaagagt agcaaaagaa
    24121 tttgcagaga atgaaatagc accaatagct gctgaaacag acaaaacagg tatttttcca
    24181 agggagcttt ttagcaaaat ggctaaaata ggatttaatg gaattggaac acctgtagag
    24241 tatagtggtt ctggtggggc agatatagaa aaggtaattg ttgttactga gattgccaaa
    24301 aaatgtgcag catctgcagc aatattatca atacacacaa tatatgctca agctattttg
    24361 aaatttggta ctgaggaaca aaagaaaaaa taccttccaa tgatggctga aggtgggtgt
    24421 gtaggtgctt ttgccttaac cgaacctaat gctggttcag atgctgcgag agctgcaaca
    24481 actgcaatta ttgatgaaga aactgatgaa tatgttttaa atggaactaa gtgttttatt
    24541 tctggtggag gtcaagcaga atcattaata atatttgcat tgacagaccc atcaaaggga
    24601 ataaagggaa tgtctgctat cattgtcgac aaaggtactc caggtttttc aataggaaaa
    24661 attgaagaaa aaatgggtat tcatggttca gaaactgcag agttaatatt tgataactgt
    24721 agagttccaa agtctaactt attaggaaaa gaaggtaaag gatttaatat agctatgact
    24781 tgtttagatg gagcaagaat tggagttgga gctcaagctg taggaattgc tgaaggggct
    24841 ttagaagaaa gtatcaaata ttctaaagaa agagtccagt ttggcaagcc aatttcagct
    24901 ttgcaaggta ttcaatggta tatagcagat atggcgacaa tggtggaatc agcaaaatta
    24961 ttagtatatt atgctgcaga tttgaaagct agaggagaaa aacacactaa agaagctgct
    25021 atggcaaaat acaatgcgtc acgtactgca agagaggtta caaatttagc ccttcaaatc
    25081 catggtggat atggatatat gaaggattat ccattagaga gaatgtacag agatgccaaa
    25141 ataacagaaa tttacgaagg tacttcagaa atacacaaag ttgttatttc aagagcagta
    25201 ctaggatagg aggaaaagaa tgaatatagt tgtttgctta aagcaagttc cagatactaa
    25261 tgaagttaaa ataaataaag agacaggtac tctaataaga gatggtgtac caagtataat
    25321 caatccagat gatagaaatg ctttagaaga agctctaaaa atgaaagatg aactaggagc
    25381 agtgattaag gttataagca tgggacctcc tcaagctaaa agtgctttaa aagaagcttt
    25441 ggcaatggga gctgatgaag cttatttaat ctcagataga gcttttggtg gttcagatac
    25501 ttgggctaca tctacaatta ttgctgctgc tatagagaag gttggaaagt atgatgtaat
    25561 attctgcgga agacaagcta tagatggaga tacagctcag gttggaccag aggttgcaga
    25621 atttttaggg ataccacaag ttacttatgc gaaagaagta aaggttcaag atgacaaatt
    25681 actagtaact cgttatacag agacagggga ttatttaata gaagcaaaga tgccagtttt
    25741 attaactgct ataaaagagt taaacaatcc aagatatcca agtgtcaagg gaatcttaga
    25801 agcttataat aatggagatg caaagattac tgtattaaca cttgcagatt tagatgttga
    25861 tacaactcaa attggattaa agggttcacc tacaaacgtt tataagtctt ttgtaccagt
    25921 taaagacaag cataatgaaa taatagaagg tataaataaa aaagaaaaag ctgagaaact
    25981 aatagaaata ctattcgatt tgaaactagt ataggagtgt taagatgatg agagcaaaag
    26041 ttaatcaagg tataaattta aatgattata atggtgtttg ggtaatagga gagcaaaggg
    26101 aaggtaaaat taatcctgtt acgatagaac ttattggtga aggaagaaag cttgctgacc
    26161 aattaggaaa agagcttgca gttgtgatag ctggatatga agtagagaaa gaagtgaagg
    26221 aattacttca ctatagtgtt gataaagtat attacatcaa tgaccctctt cttaaagatt
    26281 tcactactga tggatatgca atttcaattg caaatttaat cgaaagaaaa aagccagagg
    26341 ttgtattggt tggtgctact tctataggaa gagatatagc gcctagaatt gcaggtaagg
    26401 ttggaacagg tctaactgct gactgtacaa aacttgaaat agattcaaca gataataagt
    26461 tattacaaac aagaccagca tttggtggaa atttaatggc cactattgtt tgtccaaaaa
    26521 atagaccaca gatgtcaaca gttcgtccag gagttatggc aaaagctgta agaaacgaat
    26581 cagagactgg aattttagaa gttgttactc cagaacttac tgaaaaaatg attagaacta
    26641 gattagtaga gatacttcca caagaaaaga aatctgtaaa tctaactgat gctagaataa
    26701 tagtatcagg gggaagagga ttaaaaagag cagaaggatt tgagcttata aaagaattgg
    26761 ctgataaatt gggggcagag attggtgctt caagagcagc agtagattca gggtggatag
    26821 aacattctca tcaagtggga caaacaggaa ctactgttag accagaacta tacattgcat
    26881 gtggaatatc tggagcaata caacatttag caggtatgag tgattctaaa tatatagttg
    26941 ctataaataa agatgcaaaa gcccctattt ttagtatatg tgactatgga atagtaggag
    27001 atttatatga aattatacct gaaatgatag aatcattaaa taggtaactt ttagaaaaca
    27061 ttgaatatgt agaatgataa gtcttataat attgtattgt aagacttatt atttttgctg
    27121 aaggttatag tggggagatg aaacaatgaa agagcagtgg tataaggata tatttgcaag
    27181 agtattatct atgactgatg atggttttat tgttgtaaat acaagtggag taataataga
    27241 tattaatgat aaatattgtg actttttagg aaaagaaaga aaagatataa taggacaaaa
    27301 tatacaaagt attataccaa atacaaaaat gctagatgtt atgaaaaata agtattgtga
    27361 agaaggagct atacatcatt attcaggtgg aaatacaaaa gaaaaaagtg taatagtaag
    27421 taggtcttat gtggaaaatg acaatggaga agtagttgca ggagtagctc aagttaaatt
    27481 tagattgcaa tcatttgatg tagctaaaaa gttaatgtca gaatatatgg agctccaata
    27541 ttataaagag cagtttaagg ataactgtgg ttttgacaag ctcataggtg aaaatagaga
    27601 cttcatagaa cttaagaaaa caggtgtgaa agcttctaaa acaaactttc cagtactttt
    27661 aacgggtgaa acaggcacag gtaaagaagt ttttgctaga gcaattcaca ataatagcag
    27721 taggtcagat aaacctatgg ttagtataaa ttgcgctgca ataccagaag aattattaga
    27781 gtcagagcta tttggctatg acgaaggagc ttttacagga gcaaaaaagg gtggtaaaaa
    27841 aggtaaattt ttagttgcga ataatggtac aatcttttta gacgagatag gtgacatgcc
    27901 tttgaccatg caagcaaaac ttttaagagt tcttcaggaa agtgagatag aaccagtggg
    27961 aggtcttaaa actataaaga tagatgtaag agtaatctct gccacaagaa agaatttaag
    28021 taaaatggtt gaagagggat tatttagaga agacctatac tatagattaa atgtaataaa
    28081 cattcatatg atggaattga aggacaggca agatgatatt ttattgctag caaattatat
    28141 attaaacaaa ttaaatgttg aatacaagga attgaaggtt ttaagtgata aggttaaaaa
    28201 ttgttttatt aactatactt ggccgggaaa tataagagaa ctacaaaatg taataaaaag
    28261 tgcctatgct gtaagtgatg atatggtcat tatgatgtgt gaccttccat ctaagatgga
    28321 taatatcagc agagtagctc aatgtaatgt ggatagcaat tgttcaattc atgaaatggt
    28381 tgagaattat gaaaagagct taattattga tgtgttaagg aagtataatt ggaaatgttc
    28441 taaggcagca gaggttatgg gaatacacaa gagtctttta tataagaaaa taaaaaagta
    28501 tgaaattgaa ttaaataatt aagataactt gaattaaggc aatgctaaaa aagcgccctt
    28561 attcaaagcg aactgtataa actgttttat gcagttaaaa cgtgtaaaag tagatgtgaa
    28621 gtactaatgt caatcattag tactttttta ttatatttat aattactatc tatatttcag
    28681 tatcttttga tatctaagat tattatgttt aatttagtat ataacaaaac cctcttagtt
    28741 atggacagtt ttttatattt taactgtcta ctaagagggg atagtttagt ttaaatttag
    28801 agtaaatttt atctagcatt tataaaaaat attttgaata gcttttttgt tatttagtca
    28861 taattttcta cttctttatc aagttctttg ccacaagaat cacacttata tatagcattg
    28921 tatccgtaat catattcatc aactattttc ttttgtctaa atacaccacc acactcacat
    28981 aggaaaccaa tttttataag tgtaacgata aattgtgatt ttataaattt tatatcattg
    29041 catttatcgt tagtgtaaaa tgtataaata taagagttat cgcactcatc tcttaattca
    29101 aatctttcaa tatatgtgtt attttttaat tcctcaaatt cttctttagt taaatatgat
    29161 ttttgttgca attcatgtaa acgcttaatt tggtccatta tttatatcct cccaataatt
    29221 ttagtatttt aagcttagat aaggaatcta agttttatta aatttatccc aaggaattat
    29281 ttaaatcata tttagtttta ttaattacaa catatataaa ttacacgaaa ataaaactaa
    29341 ttgtaaaaat aatatcctgt gaaaacctaa actactaacc ccttactaac ccgaaaacta
    29401 aaaaaagaaa atatatccaa atataagtga tatataaata aagatgtttc atataaattt
    29461 aactttaaat attctgacaa taatatatat aaatatatta tagttaaaat ataccacata
    29521 ttttgggtat tgtatactgg aattagagta attaatttat tttttaacat acaaatgatt
    29581 ttatgaaaaa aaacaagact caaaaatttt tatattcttt gatagaataa aattgagagt
    29641 aaatttattg aattttataa aatttataag gggtgagtct aagatatgca tgaagataaa
    29701 aatgatatat ttgaatcaat agatactgag gattttgata ataaaacaga agaagaatgt
    29761 ttagagctag taagaaaaaa tggattgaat ttaatataca taaaaaatca aacagaagag
    29821 atatgtctag aggctgttag acaaaattgt aatgcaataa aatgtgttca gaatcagaca
    29881 gaaaaaatat gtatagaagc agttaaacaa gattggagaa tgttagaatt tgtggaagag
    29941 ccaacagaag aaatttgcat gttggctatt aaccaagatg gaacagcatt aaaatatata
    30001 gaaaatcaga cagaggagtt atgcttaaga gccgttgaaa aaaatggtgc agctttggag
    30061 tatgtaaaag aacaaacaga agaaatatgt atagaagcag ttagaaacag cgaatttgga
    30121 ttggcaagag tgaaaaatca aacagaaaaa atatgtatgg aagcagttaa gcattgtagc
    30181 tataatctaa aatgggtaga aaatcaaaca gaagaaatat gtatggaagc agtgagacaa
    30241 aatgggcttg atttgaaatt tgtaaaaaat caaacagaaa caatctgttt aagagcagta
    30301 agacaaaatg gaatggcatt agaatttgta aaggaacaga ctgttggtat atgcttaaag
    30361 gcagtaagac aatatggaat ggcattaaaa tttgtaaaag aacaaacaga agaaatttgt
    30421 acagaagcta taaaacaaga taaaagagca cttagttttg taaaaggaga taaggaaaaa
    30481 tacaaggctc tatatgataa taatgaacca tttgcaaaga gatatgttag aaatgtaata
    30541 gaaaaagaaa acagagcatt gattaaaaaa ggagaagaaa atgcaaaaat caaaattgca
    30601 ggaaaacttt atgatagagg catgtctttt gaagatatat cagatatagt tgagattgaa
    30661 ataagcaagt taaaagtgag tttaggtgtt ttttaaagta ataaatgtag gtgtttttta
    30721 tgggaaatag ttaataaaaa aataatcgac tagctctttg taggacagca aaattagtga
    30781 tataatttga tgtataataa attattttta ttagataagg gggaattaaa gttgaagatt
    30841 acagtattat accaaacaag aagtggaaac acagaaaggg tcgctaagct gatagaagat
    30901 ggagctaaaa aggtggatgg agtagatgta aagcttatga gacttgataa tattgattta
    30961 gattatttaa atgaaagtaa agcagtaata tttggaacac ctacttattt agcaaataca
    31021 acttgggaag taaaaaaatg gtttgatgaa gattcaaaaa aagttaattt agctggaaaa
    31081 ttaggagctg tttttgctac atgtgattat atatgtggag gtccagatgt tgcgatactt
    31141 actatagtag gacatttgat ggttaaaggg atgcttgtgt attctggagg tggttcttta
    31201 ggaaagccat ttatacattt aggacatgta cattcaattg aaggtccaga gttacaagat
    31261 gagaaggcta taatatttgg tgaaagaatt gctactaagg caaaagaact atttgcttaa
    31321 tttctatatg cataataatg attagagtaa atttagggtt ttaatggaga tttgaagtaa
    31381 aagttataaa ataaaaaatt ttccataaaa ttactcaaga tgaattataa tataattata
    31441 aataaattat attattaaaa tatttaaaat caaacgtcaa tagcgaggga agtttatggt
    31501 atggcatata gaatatgaga ttttttctgc aattatagtt atttttttaa tggtatactt
    31561 ttttagaagt aaatttatac ctactttaca aaacaaaata tattgtgcac ttttaatatt
    31621 ctcattttta tttataattt caaatatttt aggttcattt tgtctaaata atatagacaa
    31681 aattccaatt tttattactt ttttattgaa tcagatatac ttattgttat tgccaatacc
    31741 agcagcactt gtatcatttt atgttatggc tattatttat caagatataa ggtatatgaa
    31801 aaaaagatta ttatttttat ctataccact tataatttgt ataatcttat ctattacaaa
    31861 tccttttacg catattctat ttggattgtc aaaagaaaca ggttatatac gaggttgtgg
    31921 atatgttgca acttttgcat cttttttctt ttatgcaata tattcagcat ttttatcttt
    31981 taaatataga aaagcaatgc atgaatcaaa aatatgggct attagaggtt ttcttatagt
    32041 ttcaattgtg gcaattatct tacaggcaat ttttttacag tatcttctta caggaactgc
    32101 atgtgcatgt agtttacttt tgacatatct ttctatgcag aatcgaggtc ttattattga
    32161 tgaccttact ggtgtactca atagacaatc ttttattcaa gagctagatt tgaatatcaa
    32221 tactgaacaa tcaggattta ttattacaat tgcgcttgat gattttaagt ttatgaatga
    32281 aacttttgga acaaaaaatg gagatattgc actagaagaa gttggaaaat atttgattca
    32341 gatacatgat gtaaaccatg tatatagaat agggggagat atattttcta ttgttgtcaa
    32401 tagtcaatta ggtatagaac cagatgatat tatcagaaag atagaagaaa gatttaaaaa
    32461 gccttggcta gtagaagaga taagttttaa tttagcaact agtattgctg ttgtttatta
    32521 cccagaaaat gcagaaacga cagaagatgt aattgttgct atagatttct ctatacatga
    32581 agcaaaacgc tctgagtcaa ggcgagttgt ttatgcagat gcgtctataa gtgaaaagat
    32641 aaagaagaaa catgttatta aaaattgttt aaaagaagca ttaaaaaatg atgggtttga
    32701 agtgtactac caacctatat tttctaatag caggggcagg tttacttcag cagaggcatt
    32761 acttaggcta gaacacaaag agttaggttt tatacctcct gatgaattta ttccaattgc
    32821 agaacaaaca ggattgatta actcaattgg attagtagtc tttgagaagg tatgtagatt
    32881 tatagctagt gatgagtttg aagatttaaa attggataat atagctgtga atctttctgt
    32941 agtacaatgt atgcaaaaaa acttagctga tgatttactt tatcttatga ataaatataa
    33001 tgtatcacca actaaattta aacttgaaat tactgagact gtggctatgg gctcttttaa
    33061 tataattaaa gaaacaatgg aaagattaat tgatttaggt gttaagtttg cacttgatga
    33121 ttttggaatt gcttattctg gagttactaa tatgctttct ttaccatttt cagtaattaa
    33181 gttagataag agtttgattt ggtctatgaa tgaagatagt aggcataaac ttacagttga
    33241 gacgattata gcacttataa ataaattgaa tatgaaggct gtagcagaag gtgttgaaac
    33301 cattaagtgt gctgaagatt taatagctat ggagtgtgaa tatttgcaag ggtattattt
    33361 ttctaaacca gttccagaag atgtttttaa aaatttgttg aaagaaaata cttttacaag
    33421 ttaacaccct ttattttttt aattacaact ttgttcattg acactgccag cgatatatta
    33481 taaaattaac acaataataa atattaaatt tattatacat attattaata ttaattaatg
    33541 gagtaaagat ttattatata ttttatttaa ttatcctaaa gtgagaaagg aagatgtgac
    33601 atgaataaaa agaaaatatt agtgccaatt gatgggacag aaagaagtat gcattctttg
    33661 gaatttataa aaggaatatt taaaaaagat gaagttgaag tagaaataat gaatgtaaaa
    33721 gaactagtat ttattgatgg catatccctg gctgaagaga taaaaaattc tgaaaattta
    33781 ggaagaagaa tcttggataa agcagcagag ataatgggag agtatgatgt taaagtacat
    33841 tttacttttg gatatccagg agatgagata attagaaaag caaaagaaga taatgtagat
    33901 tttatagtta tgacaaaatc tactaaaaaa ggtcttacaa gaatgatagg ttcagtaaca
    33961 gcaagtgtag ttaaacaagc aaaatgtata gtgatgattg taccggagta gaattagaaa
    34021 ggtatttgaa atatgaataa aaagatagta gcagtttgtg aaagtgaaag aagtttaaat
    34081 tctcttaaga cagctgcaaa tgatttagga tttgatttag tttatgaaat tcaagaaaat
    34141 gataatataa aaaatgaact ttctatttat gatatagaag atgcatccat agtgttattt
    34201 gttacaagtg attctataga aagcatagag aagattgata gatttataga tagagaattt
    34261 tatgaagttg atccaaagta tataatagag gatgcaaaat ctatagtaag tgaaatttta
    34321 atagacttaa attaatcgtg ggtgtcgcac taagaataga gcgacgcctt tttatatatt
    34381 ttacacaaga aataaagagg ttgtatcaaa atatagataa gactcttttt cattgttgaa
    34441 atgatgaaaa tatatttgat ttcatacaaa aaagagtacc tcataactaa aaagttcact
    34501 ttgagacact ccatttttat atgttagttg catttaaggt aaaatataag tttaatcatg
    34561 ttgaaataac tgaattacat cttctaaatg attgtacatt gatgtataac ctaagtaaga
    34621 gtctttacta tcaaatgcca tcattatctt gttatggtgg ctaatcatat ccttgagaga
    34681 atttctatat ttaaaaccga agtattggtt agaagaaact gttttaggta ttaactcata
    34741 atattttata aaaattggat tatgagaagc taaaattatc tctttgtgaa attgcaagtc
    34801 agcatcataa cattcttcta tcaaaccatg agaaacctta tccaattcct ctattgactt
    34861 taggtaagta tattttattt tttgaagttc tttagatgta gcatttaaaa ttgctagttt
    34921 agtagcttcg ctttcgataa gttgtcttgc tcttaaagat tctacataaa attcttgtat
    34981 gttatgattt ttatagattt caccatcatc aaataggtca acttttttaa atccttcaac
    35041 tataggactt gaataaggca cagctctaag tattccttcc ttacagagta tatttatggc
    35101 atttcttaca ggtattctac ttatgttaaa taggtcagca atctttctct cacttggtaa
    35161 tttactatta attttaaaag ttccatttag aatgtttaat ttaatataat caataatttt
    35221 ttcagtggca tttaagcttt tcataaaaac tcctaaacat ataatttttt tatgattgta
    35281 ttatatcata gttaagagtt aaatctactt ttttataata tgtataagac aggatagagg
    35341 ccaaaatagc tataatagcc aagataaagt atccatattg tattgaagta tattccgata
    35401 ttttaccaac tatcattgga aatacagaca ttcctatagc ataaattgct tgaaaaaaac
    35461 ccattgcagt agatttctga tgttttggta catttttcat agactcgcta gtaaggtaag
    35521 aaaggagtat acctgtagat atacctggta gtacttgtag tacaaatatt atattaatat
    35581 tttttattgt tgggactaaa aagcaatagg ctgaaactaa aataaaaact aaaggaatcc
    35641 aaaattttgg tccatactta gtacaaaatt tagtagaagc aaagccagaa gaagcaacag
    35701 cacacaccat gtaaaatata gaagatagac ctatgagggt agaactagaa cctaagtttt
    35761 taagaatttg agtagtaaat gacattgttg tagacatttg aataccctgt tgaattaatg
    35821 ccataaagga aaaaaataca agtcttttat ccttgcagat agataaatat tttttaattg
    35881 atattttttc aggtattttt tttgaattat gattttttat atttaaggct agaatcgttc
    35941 caataactga agacaataca ctcatgatac ataaggctgt cattcctaat ttttcataaa
    36001 ataaagtact cataacaaat ccaatcaaca ttcctagatt gtttaccaat attatcgtac
    36061 ttgtagcttt ttgttgatgt tctgtagaaa aaaagttggt atagtgaacc atgtaagaaa
    36121 tccaagttga tgatgatatt ccagataaaa tgttagctat aagaaaacca ttgcctccag
    36181 gagaaaagac tcttataaga gatgctaaac cagcaaagaa aattccagac agtataaata
    36241 ttttatgttt atttatagaa tcagcaaata ctccaacagg aagccttaat aaacattgtg
    36301 atattccata tgcacctatt attataccaa tcatatttgt agatacatta catgcactta
    36361 aatatggatt ttggaaaggt atatatacat attgtgaaaa ccagaaaaat gtaacaatag
    36421 aaagtaaaag taatttttga ttagatattt ttttcatatt atcctccata tggtattttt
    36481 ataa
//
LOCUS       DAEOTL010000039        35076 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEOTL010000039 DAEOTL010000000
VERSION     DAEOTL010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.039"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(72..845)
                     /locus_tag="KRH82_002190"
     CDS             complement(72..845)
                     /locus_tag="KRH82_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBG8655469.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(845..1231)
                     /locus_tag="KRH82_002191"
     CDS             complement(845..1231)
                     /locus_tag="KRH82_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8655470.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFYIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1256..1573)
                     /locus_tag="KRH82_002192"
     CDS             complement(1256..1573)
                     /locus_tag="KRH82_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBG8655471.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1585..1845)
                     /locus_tag="KRH82_002193"
     CDS             complement(1585..1845)
                     /locus_tag="KRH82_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBG8655472.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1845..2141)
                     /locus_tag="KRH82_002194"
     CDS             complement(1845..2141)
                     /locus_tag="KRH82_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8655473.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRH82_002195"
     CDS             complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRH82_002195"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBG8655474.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDIAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRH82_002196"
     CDS             complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRH82_002196"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBG8655475.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRH82_002197"
     CDS             complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRH82_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBG8655476.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRH82_002198"
     CDS             complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRH82_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBG8655477.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8034..9140)
                     /locus_tag="KRH82_002199"
     CDS             complement(8034..9140)
                     /locus_tag="KRH82_002199"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBG8655478.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRH82_002200"
     CDS             complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRH82_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBG8655479.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11360..11497
                     /gene="rpmH"
                     /locus_tag="KRH82_002201"
     CDS             11360..11497
                     /gene="rpmH"
                     /locus_tag="KRH82_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBG8655480.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11575..11919
                     /gene="rnpA"
                     /locus_tag="KRH82_002202"
     CDS             11575..11919
                     /gene="rnpA"
                     /locus_tag="KRH82_002202"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBG8655481.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11951..12202
                     /gene="yidD"
                     /locus_tag="KRH82_002203"
     CDS             11951..12202
                     /gene="yidD"
                     /locus_tag="KRH82_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBG8655482.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRILKCHPFHPGGYDPLK"
     gene            12234..12941
                     /locus_tag="KRH82_002204"
     CDS             12234..12941
                     /locus_tag="KRH82_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBG8655483.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12910..13539
                     /locus_tag="KRH82_002205"
     CDS             12910..13539
                     /locus_tag="KRH82_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBG8655484.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13651..15030
                     /gene="mnmE"
                     /locus_tag="KRH82_002206"
     CDS             13651..15030
                     /gene="mnmE"
                     /locus_tag="KRH82_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBG8655485.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15125..17020
                     /gene="mnmG"
                     /locus_tag="KRH82_002207"
     CDS             15125..17020
                     /gene="mnmG"
                     /locus_tag="KRH82_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBG8655486.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGDDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            17013..17732
                     /gene="rsmG"
                     /locus_tag="KRH82_002208"
     CDS             17013..17732
                     /gene="rsmG"
                     /locus_tag="KRH82_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBG8655487.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17895..18680
                     /gene="noc"
                     /locus_tag="KRH82_002209"
     CDS             17895..18680
                     /gene="noc"
                     /locus_tag="KRH82_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBG8655488.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18815..19588
                     /locus_tag="KRH82_002210"
     CDS             18815..19588
                     /locus_tag="KRH82_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBG8655489.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENIDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19590..20453
                     /locus_tag="KRH82_002211"
     CDS             19590..20453
                     /locus_tag="KRH82_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBG8655490.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20486..21628
                     /locus_tag="KRH82_002212"
     CDS             20486..21628
                     /locus_tag="KRH82_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBG8655491.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21762..22337)
                     /locus_tag="KRH82_002213"
     CDS             complement(21762..22337)
                     /locus_tag="KRH82_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBG8655492.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKAQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22597..23889
                     /locus_tag="KRH82_002214"
     CDS             22597..23889
                     /locus_tag="KRH82_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBG8655493.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSESKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            23994..24596
                     /gene="yedF"
                     /locus_tag="KRH82_002215"
     CDS             23994..24596
                     /gene="yedF"
                     /locus_tag="KRH82_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBG8655494.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24669..24932
                     /locus_tag="KRH82_002216"
     CDS             24669..24932
                     /locus_tag="KRH82_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBG8655495.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24947..25132
                     /locus_tag="KRH82_002217"
     CDS             24947..25132
                     /locus_tag="KRH82_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBG8655496.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTRCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25235..26431
                     /locus_tag="KRH82_002218"
     CDS             25235..26431
                     /locus_tag="KRH82_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8655497.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26645..26923
                     /locus_tag="KRH82_002219"
     CDS             26645..26923
                     /locus_tag="KRH82_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBG8655498.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26960..27394
                     /gene="ssb"
                     /locus_tag="KRH82_002220"
     CDS             26960..27394
                     /gene="ssb"
                     /locus_tag="KRH82_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBG8655499.1"
                     /translation="MNKVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27413..27640
                     /locus_tag="KRH82_002221"
     CDS             27413..27640
                     /locus_tag="KRH82_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBG8655500.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27783..28103
                     /locus_tag="KRH82_002222"
     CDS             27783..28103
                     /locus_tag="KRH82_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBG8655501.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28111..29067
                     /locus_tag="KRH82_002223"
     CDS             28111..29067
                     /locus_tag="KRH82_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBG8655502.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29078..31072
                     /locus_tag="KRH82_002224"
     CDS             29078..31072
                     /locus_tag="KRH82_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBG8655503.1"
                     /translation="MSNKQAFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31073..31522
                     /locus_tag="KRH82_002225"
     CDS             31073..31522
                     /locus_tag="KRH82_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBG8655504.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31541..32869
                     /gene="dnaB"
                     /locus_tag="KRH82_002226"
     CDS             31541..32869
                     /gene="dnaB"
                     /locus_tag="KRH82_002226"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBG8655505.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33074..33382
                     /locus_tag="KRH82_002227"
     CDS             33074..33382
                     /locus_tag="KRH82_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655506.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33464..34753
                     /locus_tag="KRH82_002228"
     CDS             33464..34753
                     /locus_tag="KRH82_002228"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBG8655507.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
BASE COUNT        13298 a         4509 c         5542 g        11727 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata ccatctttaa aacagtaggt caatactttt
       61 tttatatttt tttataaatt tttttcatat tcttttttca gcttctctac tacctttttc
      121 tctagtctag aaacagtcat ctgtgatatc cctagttctt tagctatact agattgtgtt
      181 ttatcaaaga aaaatctatc tttaaaaatt ttaacttcta attcatttaa agtttcaata
      241 aacttattaa taaaatcttc atactctata cttccaaagt taccttcttc ttttccaatc
      301 ttatcaataa gagttatatc tttatcctct gaatcatcat tacttgatga atccaaagac
      361 attggttgat atccataaga agcctccata gcctctaaaa catcttcttc actaacgcct
      421 atataatcag ctatatcttt tacctttgga tgcttcttat tttcttgttc taatttaatc
      481 ttcgcatcac ttatcttttt gcttaattcc tgtattcttc ttgggactct aagtgtccat
      541 actttatctc taaaatactt ttttatttct cctactatag ttggtgttgc aaagctggag
      601 aactcaaatc ctttctcaac atcatatcta tcaatagcat aaattaatgc caatgaagca
      661 acttgatata tatcttcaaa atcaacacct ttgtttatat acttcttagc taacaatctt
      721 gctaaataca gatgtctttc aataagaata tttctaatgt ctacattttt atttttatta
      781 tataaattaa atagctcttt tgtatccata tttaggtaat gtgtagcatt agctacattt
      841 ttcattaaat atcaactcct aaatatttag tcatttttat ttttgtccct tgattatgtt
      901 ctgattcaat atctacatca tccattaaag ttttaattat aaacaatcca agaccactct
      961 cttttggatt ctctaaatct ggtgtactta ttgagctaac atcatatcct tttccattat
     1021 cttgaatttc tatattaatt gcattatcta aaatattaaa tactatataa aacacatcat
     1081 ctttactgtg ttttattgca tttgtacatg cttcagatac tgctaccttt atatcttcta
     1141 tatcatctat tggaaaaccc atcttattgg caattccaga tgctgttaat cttattatac
     1201 taacataatc tggatttgta gtaatttcca tctttatagt ctcacaagcc aaagtttatc
     1261 cctccacttt aaatatttta tctagacctg ttatagtaaa aatctttctt acgttactct
     1321 taggatttac tatgtatatc tctttttcat ttatttttaa tttttttaat acacctatca
     1381 tagctcctaa gcctgttgag tctatataat ctaaatcttt aagattaatc tttacatcta
     1441 acatattttt ttctattaaa gcatgtaaat gttcctttag tttatctgct gtagaaacat
     1501 caagttctcc atcaagacaa acattccaaa atttattttg tgaatctaaa tttgaatcaa
     1561 tattcataga catgtaaaaa cctcctattt ccttttaata attttaaata tatttcctat
     1621 actcaatatt ttattaatta cataaactat atcatctatt ccctttgata ttgatgatgc
     1681 attttcaaca atatcttgta tatgtctttc attataatct acaatcttat atgccttttc
     1741 aacaacctta tttatgctgt ttagagtttt agctaaataa attgctacta taagagcaga
     1801 gcttcctact aacactgctc caatttgcca cccccatgca ttcattagtt aacatctccc
     1861 tcatcatcaa agcttttact tattactata tcttcttctg aaatctttat atcttcttca
     1921 ttattatcat catccactaa atttattatt ctctctttaa catcattaaa tgtttcatgt
     1981 agaacttctt ttggattttc tttaacatca ttaaacttct cttttgtttc ttttcttagt
     2041 tcagaacctt ttttaggtgc aaaaaacata ccaaatataa accctaaaat agctcctaat
     2101 aataaaaatc cacctttttt acaacttctt ttattgcaca taacaattac tcctttcaat
     2161 tttaaatttt tatctaacta cattatacaa aaagaatagg atatttatcc tattcttctt
     2221 caatatttat tttggcaatc gaaactacat tgacttcatc attcgtcttc attaatttaa
     2281 caccacttgt aactcttcca aacagtgata tttcattgac tcttattcta ataagaactc
     2341 catcagaatt tataatcatt atctcatcat cttcgttgac catatctgca cctacaattg
     2401 taccagtttt ttcagatata ttataagttt taattccttt accagctctt atttgacttc
     2461 tatactcttc tatatttgtt ctctttccaa aaccattctt acttacaact aacacatctg
     2521 tacctttact gcaaaggttc atagacacaa caaaatcttc tttacttaaa gttatacctt
     2581 ttacacccat tgctgttcta cccatatatc ttatatcatt ttcatcaaat cttatagaca
     2641 taccttcttt agttactaaa agtacttctt gttttccatc tgtaagttct actccaataa
     2701 gctcatcatc atctcttaaa cctatagcaa taagaccaga tttatttata tttttgaact
     2761 cttctctctt agtcttttta acaatacctt ttttcgttgc aagtaataaa tattcatttt
     2821 catcattacc atcaataggt attagagtag caattttctc atctgctgac aattgaagta
     2881 aattcactat agcagtacct ttagcctgtc tcttaccttc tggtatttca tatgcattta
     2941 atttaaatac tctaccttta tttgtaaaga ataatagtct actatgagta gttgtagtta
     3001 ccaagtgcct tacaaaatct tcttctctag ttgtaagtgc tgaaatacct cttccacccc
     3061 ttttttgact cttataagta tcagatggaa gcctttttat atatccaaag tgagtaagag
     3121 ttattgctat ttcttcatca cttataagat ctctcatatc tatttcgcct tcagcatgtc
     3181 ttatttctgt tcttctctca tcagagtaat tttcttttat tattgtaatt tcatccttta
     3241 ttacatttaa aagtaatctt tcatcagcta aaatctcttt taatctattt atcttcttga
     3301 ttaaatcttc atattcagct tctatcttat ctctttctaa acctgtaagt ctttgaagtc
     3361 tcatatctaa tatagcttgt gcttggattt cagttaattt gaatttttct attaaaccta
     3421 gcttagcttc ttgcccagtc tttgaagctc ttatcaagct tataacagca tctatattat
     3481 ctaaagcaat ctttaatcct tctaaaatat gtgctcttgc ttcagcttta tttagttcaa
     3541 atttagttct tcttgtaaca acatcttctt gatgtttaat ataatgatat aatatttgtt
     3601 taagatttaa aactcttggc tgaccatcta caagtgcaag cattattata ctaaaagtat
     3661 cttccatttg agaatgttta tacaaattat ttaatactat attagcatta gcatccctct
     3721 ttaattctat aacaattctc ataccatttc tattactttc gtctcttagg tctgatatac
     3781 cttctattct cttttcttta actaactctg ctattctttc aacgagttta gccttattta
     3841 cttgataagg tatttctgta actattattt gctgttttcc ttttggtagc tcttctataa
     3901 aagctctaga cctaacttta acttttcctc ttccagttct gtatgcttct gctatacttt
     3961 cttttcccat tataattgca gctgtaggga aatctggtcc ttgaacaaat tttattaaat
     4021 catctacact acactctgga ttatctatca aatatacagt tgcatcaatt acttctgcta
     4081 aattatgtgg aggtattgaa gttgccatac caacagctat accatttgag ccatttacta
     4141 ataaattagg atatctagct ggcaatactg aaggctcttt taacgactca tcaaagtttg
     4201 gtttaaagtc tacagtttcc ttttcaatat ctcttagtag ttctaatgat aatttactca
     4261 ttttagcttc tgtataacgc atagcagctg gtgaatcccc atcaacagaa ccaaagttac
     4321 catgaccatc tactaaaagt gctctagttg aaaaatcttg tgccattctt accatagcat
     4381 aataaacagc aatatctcca tgaggatggt acttacctaa aacgtcccca acaatacgag
     4441 ctgacttcct gtatggttta tctggagtta aatttaactc actcattgaa tataatattc
     4501 ttctatgaac tggctttaaa ccatctctaa catcaggaag agcacgtcca gctataacac
     4561 tcattgaata atcaatatac gattttttca tttcttccgc tatttcaata gggagtattt
     4621 tgttattttc ttccatgtat actaatcccc tctctctata tatctaagtt tctaacaaat
     4681 cttgcatttt cttctataaa ttcttttctt ggagcaacct tatcacccat aagcattgaa
     4741 aatacttcat ctgcaattgc agcatcttct acagtaactt gtaataaagt tcttgtctca
     4801 ggattcatag ttgtttccca taattgctct gcattcatct ctccaagacc tttgtacctt
     4861 tgaagttcaa caccatttct tccaatttca tctagtaaga tatttaactc tttatctgag
     4921 taaacataat gttccttctt ttgctttgtc actttatata aaggtggctg tgctgcataa
     4981 acatacccct catctataag aggtctcata tatctaaaga agaatgttaa taataaagtt
     5041 cttatatggg ctccgtctac atcagcatcg gtcataatta taattttatg atacctagcc
     5101 ttatctatat caaaatcttc tccaatacca caaccataag ctgttatcat attttttatt
     5161 tcatctgaag atagtatcct atctagtctt gatttctcaa cattaagtat tttccctctt
     5221 aatggaagta tagcttgact atttctatct ctaccttgtt tagctgaacc tcccgctgaa
     5281 tccccttcga ctaagaatat ttcactttta gatggatctt tttctgcaca atctgcaagt
     5341 tttccaggta aagatgtact ttctaataca ctttttctcc ttgttaattc tcttgctttt
     5401 tttgcagctt ctctagctct ttgtgctctt aaagctttat caactatgat tcttgctgtt
     5461 gatgggtttt cttctaggaa agaccccagt tcatcaactg ttacactatc aactatacct
     5521 ctcataaagc tattacctag ctttgtttta gtttgacctt caaattgagg ttctggtaat
     5581 ttaactgata ctactgctgt aagaccttct cttatgtctt caccaagtag gttaacatca
     5641 ttttccttta aaaatttatt tctcttagca taatcattta cagttttagt aagagctgct
     5701 ttaaatccac ttaaatgaga accaccttca tgtgtattta tattgtttgc aaaagaatat
     5761 atgttctctg tataaccatc tgtatattgc atagctagtt caacaaaaca atcatcaacc
     5821 tttttatcta tataaactat gtcatcatgt ataccagttc tagatttatt taaatactta
     5881 atatattcta ccaaaccacc tgtatagtga aattcttttc ttttttcttg tccttctctt
     5941 ttatcttcaa atactatttt tattccttta ttcaagaaag aaagttctct aagcctatac
     6001 tccaatgttt catatttaaa ctctatttca tcaaatattg tctcatctgg cataaattga
     6061 atcattgttc ctttatcttg agattctcca actacttcaa gcttagatgt tggcaatcct
     6121 ttctcatatg tctgcttata tatctttccg tttaaataaa cctctgctac catccatttt
     6181 gacaatgcat taactacaga aacaccaact ccatgaagac ctccagatac tttatatcct
     6241 ccgcctccaa actttcctcc tgcatgaaga ttagttaata ctgtttctaa agttgattta
     6301 ccagttttag gatgtatttc aacaggtata cctcttccgt tatcttttac taaaacactg
     6361 ccatcttcat taatagatac atatatgtct gaacaatatc cttgtaaagc ctcatctata
     6421 ctattatcta caacttcata aactaagtga tgtaaacctc tagggcttgt actaccaata
     6481 tacatacctg gtctttttct aacggcttct aatccctcta atacttgtat ctgacttgca
     6541 ccgtattctt gtttcattta atttcctcca ttctctatgc taataacatc gccattttca
     6601 atattaaata ttgtaacatt tttttcatca aatatttttt tatgtgaaac ttcagcactt
     6661 gttataaaca tttgaacatt gcttaaatta tttactaaaa gtttttgtct tgcttcatct
     6721 aactcactaa aaacatcatc taaaattaat actggatatt cttcaacttc attttttatt
     6781 aattctatct ctgataactt taatgatatt gaagcagttc tttgttgacc ttgtgaacca
     6841 aaaagtcttg catctaaatc atttatgaat atatttaagt catctttgtg tataccatat
     6901 ctggtagtct tagattctat atcattaggt ctattcgatg acaacttggc taaaaattta
     6961 ttatatactg tatctatagt atcttcatca gttatattta tttgattttt atatcgaatt
     7021 gataatcttt caactccatt agtcaaattc atatgcatat tttcagatat attagctatc
     7081 ttttttataa agtctctacg caaaatataa atataacttc catactttgc taacgtatca
     7141 tcatatacat ctaataaagc ttcatcaaca tgtatatttt taagcaccct actcctttga
     7201 gaaagtgttt tattataatt ggtaagatat ttataatatt taggtataat ctgactaatc
     7261 tctttgtcta taaatgccct tctttcttta ggaccctctt taaccaacct taaatcctca
     7321 ggagaaaata taacaacatt taagttgcca agtagttctt gtatcttttg taaaggaact
     7381 ttatttattc ttatcccttt tttatctttt ccaataatta gctctattag actatattta
     7441 ttatattttg aaaaacttcc tccaatatat aagttttcac tattaaatct aaccatttct
     7501 ttatctttgt tagtcctaaa tgattttcca aaagaaagca tataaataga ttctactata
     7561 tttgtctttc cttgaccatt tttaccaaca agtagattta ctttcccatt aaattccaga
     7621 tgcaactttt tataatttct aaaattaaca agttgcaaac ttttaagttt cacaaaaagt
     7681 tctccttttt ttacaatact tttattttag ttccttctat ttcaactata tctcctgatt
     7741 ttatcttttt tcctcttctt aattctattt catcatttac tgtcactaaa ccttcttgaa
     7801 ttaaaaattt tgcatgacct cctgttgatg caatctctgc taatttaaga aattgatcca
     7861 actttatata ttctgattct atagttattt cagtcataat agttcctcct tgtcactatt
     7921 ttaaacaaat tcctattgat acactaaaag tatattatac cataaatatg cttataaaag
     7981 gagttgtcta agattagaaa aattttctac aaaagacaac tccttcatgt ctgctatata
     8041 tttgatgata ttcttactgg aagcagtaag taaatataat taacatcatc tgttggttta
     8101 attatacaag gatttacatt tgtagtaaat tctataaata tttcctcatt atctatattt
     8161 ttcaaacctt cgataaaata tctagaattg aaagctatat ctaggtaatc tccatctaaa
     8221 tctatttcaa cttcttcata cacatttcct ttttctgtat tagaagtaat tgccattact
     8281 ttatctctta tagataactt tataagatta tttttttctg attgagacaa taaagacgct
     8341 ctctctatac tatttaaaag ttccttagta tttaatttaa ctctgctgtt atgttctctt
     8401 ggcaataatt ttttataatc aataaaatct ccttcaagca atcttgtaat aattttcgta
     8461 tcattaatta taaaaatagc atttttttcg ttaaatccaa ctttaacatt atcctctcca
     8521 gaaagcaaac tatttacatc tataagtgtc tttccaggaa ttatgacttt tatattttca
     8581 gttaaactat caaccgaaca actttttaca gctaatctat atccatcaat tgctactaaa
     8641 tttaagtttc tatctacaat ttctaaaagt tctcccatta aaacaggttt tgtttggtcc
     8701 tgtgagatag caaatacagt ttgtttaatc atatttttta ggatttcttg aggtatgcta
     8761 tataaatctt cttcatttaa ttctggtaat ttaggaaatt cttttgctgc ataaccttta
     8821 attttaaatc ttgaatttac acaatttatg taaatattat tttctgaatc agtttctatc
     8881 tcaacaaagg aatctggtaa ttttctaatt atatctccaa atagccttgc atctacaaca
     8941 acatcacctt tttctatgat ttctgcttgt acataagttt ctattcctat ttcagcatca
     9001 tatccagtaa gttttaattg accttcttct gtagatataa gtataccttt taataattct
     9061 attgttgttt ttccattaat agctttttga gcaattccaa ttctatttgc taggattttt
     9121 tgattacaaa ttattttcaa tgtggataac ctcctctggc tttttatata taaaaataag
     9181 ttaaaatcat agtagtaata gtagtaggtg ttgttgataa tgttaataag tatgtataac
     9241 attataaata caaagatatt aacatgtgta taagatgtta atatctttgt tattttagac
     9301 ttgataattt gttaataatt tttgttcaaa aaaagtatta acaggttatt caagagatat
     9361 aaacatacaa ttgtgtataa attatccctt caaatctgat ataattttgt ctattttagt
     9421 cttaatttct tcactttctt ctatatcctt agatactttg tcatgagcat gaattactgt
     9481 tgtatggtct ctacccccaa actcttcacc tattttagga agggataaat cagtaagctc
     9541 gcgcgttaaa tacatagcta tctgtcttgg ataagctatt gaacgtgttc tttttttaga
     9601 attaaaatct tccatcttta aattgaatac agaagatact ttttctttta ttctgagaac
     9661 atttatttct tcatttttag aagttgttat aatatctttt aaagcttctg tagcaagatc
     9721 aaaagatatt accctattgc taagagaaga ataagcaacc actctagtta atgcaccttc
     9781 tagttccctt atgtttgact taatattttt tgctatatat gacataacct catttggcac
     9841 atctatacgt tctagttgag ccttttttct aagtatagca attcttgtct caaagtcagg
     9901 tgcttgaata tcagttataa gtcccatttc aaatctcgat cttagcctat cttctagtgt
     9961 aggtatgtct tttggcggtc tatcactaga tataattatt tgtttgtttg cttcatgaag
    10021 agtattgaat gtatggaaaa actcttcttg agttctttct tttcctgcta taaattgaat
    10081 atcgtcgatt agtaatacat ctacgtttct atatttattc ctaaattctt cgtttttatc
    10141 gtcttttata gagtttataa gttcattagt aaatttttct gaagaaacgt aaactacttt
    10201 tgagtctttt ttttgactaa caatatgatg acctatagca tgcattaggt gagtcttacc
    10261 taatccaact cctccataca aaaaaagtgg gttataagct ttagctggag attctgcaac
    10321 tgcaacgcat gcagcatgtg caaatctatt gctattacca ataacgaatg tatcaaatgt
    10381 gtattttgga tttagattgg ggtaaagaac tctataattt aaatctgtgc tatcagaatt
    10441 taaatcagca acctcttttt cgctcaatac aaatttaata ttatattttt ttaatgacag
    10501 ttgactaata gcatcttcaa ttaaatgtaa atatctattc tctaagatat ctttattaaa
    10561 atcactagga gccagtaaga ttaaatcatt aagatgtatt tttaatggta cgatgttttt
    10621 aaaaaaggta ttaaaactta ctgaagttaa gtcacctttt attaattgta gggttttgtc
    10681 ccataaagaa actatatcca taatataaac ctccgaacag aataattaat attttccaca
    10741 aagttattaa cagaaaagca aaaatatata taaattttac agaataacta aatttatgga
    10801 taatggtgtt gataaattaa taatagtata aattattaaa aaaatatgaa aagatataaa
    10861 caatatgtag ataaagttat aaataacata aacatacaat aaatggtgat tataactaga
    10921 gtattgtcag taatcttaaa agttatacac aaaagtatcc acaagctgtg aataatttct
    10981 aataagttga taacatttat gcacattatc aacaagtata tttataatat caaaatatat
    11041 gtcaaacttc aatgatttgt aactaattta tccacaatat taactaattg ttgataaaaa
    11101 tataaacatg ttaaaattac tttatttgtg tatataattg aaaaaaataa tttagaataa
    11161 aattaaatag atttttacta gtattttcaa taaaaaaaat acataatata tatatggtag
    11221 attttgtgat ataagcgtcc caaaaactcg ttgacaacag tagtaaaagt atttataatt
    11281 atatgtgtta tgtttacttt gagggtaaag ttattatttt tataaacgga aaataaaatc
    11341 tgaaaggcgg tgcaaaataa tgagtaaaag aacttatcaa ccaaaaaaga gacaaagaag
    11401 taaagaacat ggtttcagaa aaagaatgaa gacgtctaac ggaagaaacg tgttaaagag
    11461 aagaagagct aaaggaagaa atagattaac tcattaatta caaaagggcc gctgcaaagg
    11521 tggccttttt gtgtaaataa ttacaattca tagctgtgtt tatggaggtt aactatggac
    11581 tttaatagga ctaaagggtt gaaaaaagac tctgatttta gaaaagtata taaacacggc
    11641 aaatcttttg caaacaaata tttagtaata tatatactta aaaataaatc agattatagt
    11701 agagtaggta tttctgtttc aaaaaaagta ggaaaagcta ttactaggaa tagagtaaga
    11761 agattaataa aagaagccta cagattaaat attgatgaaa aaattaagcc tggatatgat
    11821 atagtattta tagcaagggt atctagtaag gatgctactt ttaaagacat agacaagtct
    11881 ataaaaaatt tagttaaaag aacggatatt tctatttaat tgtatgctat aaatatggag
    11941 gttaatgact ttgaataaaa taatttatat attaaaggaa ataagtaagt atttatcgaa
    12001 tttatgtatt tatttagtga gattttatca aaagtatata tctcccttaa agggacctac
    12061 ctgtagattt tatccaactt gctcacaata ttcaatagag gcgtttaaga aatatggatt
    12121 tgtaaaaggt atgtatttaa cgataagaag aattttaaaa tgtcatcctt ttcatccagg
    12181 aggttacgac cctctaaaat aaaagagagt aactattagg aggtataaaa aaattgaata
    12241 taataggaaa tttcttagga ttgattctta aggtaatatt tgaatttgtt aatcattatg
    12301 gtatttctat aatacttttt acgatacttg taaagattat tttattacca ttaacaatta
    12361 agcagactaa gtcaacaaag gcaatgcaag atatacaacc tcgtataaaa gagatacaag
    12421 aaaaatataa aaataagcca gaaaaacaaa atgaagaaat tgttaagtta tatggagaag
    12481 ctaaaattaa tccactatct ggttgtttac ctttattaat acagtttcct atattaatag
    12541 gattatttag cgttttgaga gaaccagttg ctcatggcgt ttttgcaaac aaagctgcat
    12601 ttttagcagc tgacaatggg tttttatgga taaaaagctt aacatcacca gattatgtat
    12661 tagcagtatt ttcaggagca agtgcatatg tcatgcaaaa agtaatgaca ccaaaagatc
    12721 agttacaagg ctctatgaaa gtaatgacat atgtaatggc aggtatgtct ttctattggg
    12781 gatttatatt cccagcagga cttacattgt actggacagt aagtaactta ttctcaatag
    12841 ctcaatatta cttaataatg aatcctttaa aagctaaact ggctgctaac tctaaggagg
    12901 aaaaagttaa tgagaaaaag cctaaaatta ataaaaagta agagtaaaga ggaagctata
    12961 agtaaagcta tagcagagtt gaatttaaaa gcagaggata tagaagtaga aatacttgaa
    13021 aatccaagta aagggttttt aggttttata ggtgctaaag atggtactta tgaaattttt
    13081 gttatcgaga gggaagtaga tgtagctaaa aattttatag aggtaatgtt gaaaaatgca
    13141 aatgttgatg ccaaagtcaa tgtatctcaa aaagataatt taatcatggt tgatattgaa
    13201 ggcaaagaag ctgcaagttt aattggtaga agaggggaaa ctttagattc tattcaattt
    13261 ttgactggat tagctcttaa taaaataaat aaagattctc atacaagagt acttgtagat
    13321 atagaaaatt atagatcaaa acgagaagaa tctttaataa gatatgctaa taaagttgct
    13381 agagaagtag cgaaaacaag aaaaactaaa aaattagatt atatgaatcc atatgagaga
    13441 agaataatac attcagctct tcaaaatgac aaatatgtaa ttacatatag tgaaggaacc
    13501 gatccatata gaagattagt aattgagtgt aaaagataaa gtcaacctcc taaacattag
    13561 ggggttttat tttttaatat tattaaatca ttaatgattg gttaaatgta aatctatatg
    13621 taaaaaatta tgaattaaga ggtgataaat ttgtttatag atgatacaat tgcagcaata
    13681 gctacagcac ctggagaagg tggtataggt atacttagaa taagtggaga aaaagctttg
    13741 aaggttgcag aagaaatctt taaatctatg tctggaaaga gtattgaaga atacaataag
    13801 agaacattaa tatatggaaa tatagtggat aatgaaaata taattgatga agttttattg
    13861 gcatatatga aaggaccaaa ttcctataca ggagaagatg ttatagaaat taattgccat
    13921 ggtggattta tttcggtaaa gaagatatta gaattaatac tatcaaaaga tgttagatta
    13981 gcagaggctg gtgagtttac taaaagagca ttcttaaatg gaagaataga tttatctcaa
    14041 gcagaggctg taattgatgt tataaaagcc aaaactgata tagctcatga agttgctcaa
    14101 aatcaattag aaggttcttt atcaaagaag ataagagaat tgagagataa agtcactgag
    14161 atattagctc atgtagaagt tgctatagat tatcctgagg aagatattga gcatataaca
    14221 tatcaaactc ttaaagaaaa aactgatgaa cttaaaaaag acattaaaaa attatatgat
    14281 acagctgaaa gtggaaaaat acttagagaa ggcttaaaga cggtaattgt tgggaaacca
    14341 aatgtaggta aatcttcact acttaattct attttaggag agaatagagc aatagttact
    14401 gatataccag gaactactag agatgttata gaagagtttg taaacataaa aggtatacct
    14461 ttaaaaattg ttgacacagc aggtataaga gatactgatg atattgttga aaaaataggt
    14521 gttgaaaagt ctaaagaatc atttactagt gcagatttga tagtaatggt tttagatgca
    14581 tctagaaagt tgtcagaaga agatatagag atattagaaa aacttaagga taaacaaaca
    14641 atagtgctgt taaataagaa tgatttgaaa caagagattg aagaagaaaa aatacttaaa
    14701 tatgtagaaa ataatagtat aataaaaata tcagctttac aacaagaagg aatagaagaa
    14761 ttgcaagata aaatagagtc tatggtatat aaaggtagta tcaaaaataa ttctagttta
    14821 gtagtaacaa attcaagaca taaagatgca cttagtaaag catataaatc tgcaacagat
    14881 gctttaattg ctttggaaca aagtatgcca tttgactttg tagaagtcga tttaaaaaat
    14941 atatgggact atcttggata tattaatggt gatacagtaa cagaggattt actagataat
    15001 atattccata atttctgtat tggtaagtaa tgtacaaaag taaacttgtt tttattatag
    15061 agatttttaa aaaatttgaa gtgtttctca tgaaacatta attttgaaaa gaaaggaatt
    15121 ataaatgata aagtttgaag caggaaaata tgatgttata gtagtcggag caggacatgc
    15181 tggatgtgaa gctgctttgg ctactgcaag aatgggatat aaaactttga taataacaat
    15241 gtctttggat tccatagcat taatgccttg taatccatca attggaggga ctggtaaagg
    15301 tcaattagtt aaagaaatag atgccttagg cggtcagatg ggattaaata tagacaagac
    15361 atatatacaa agtagaatgt taaatactgc caaaggtcca gcggtacact ctttaagagc
    15421 acaagcagat aaatttaaat atcatgaaga aatgaaaaag acattagaag atgagccaaa
    15481 tcttgatata gctatggatg aagttgtaga aatacttcat gaaggaaatg ttgtaatagg
    15541 agttggaact aaactaggat gttcatttaa atctaaagct gtaatattgg ccactggagt
    15601 ttatctgaac tcaaagatat atatgggtga agttgcattt tatgaaggtc ctaatgcatt
    15661 ggggtatgca aaatatctta cagatagctt agttgagctt ggccttagaa tgagaagatt
    15721 taagacggga actccagcaa gagttcatag agatagtata gacttctctg taatgtcttt
    15781 acaagagggt gatgaaaaag taactccatt ctcatttatg aatgaaaata tagaaaaaaa
    15841 acaagaacct tgttatttaa caagaactac agaagaaact caaaaagtta tactggataa
    15901 tttaaaaagg tctgctatgt atagtggagt aatagaaagt actggtccaa gatactgtcc
    15961 ttctatagaa gataaagtag taagatttag tgataaaaca tcacatcaat tatttataga
    16021 accagaaggg ttaaatacta aagaaatgta tatacaagga atttcaacta gtttaccttt
    16081 tgaagttcaa ttagatatgt acaaaactat aaaaggactt gaaaattgta agataatgag
    16141 acctgcatat gctattgaat atgattgtgt tgacccaact caactaaaaa taagtttgga
    16201 aataaagggt gttgagaact tatttagtgc agggcaattt aatggaactt ctggatacga
    16261 ggaagcagca gctcaagggc ttatggctgg tataaatgca gttagaaaga tagaaggaaa
    16321 agagccattt gtattagacc gttcagaagc ttatataggt gtcttattag atgaccttgt
    16381 tactaaagga actaacgagc cttacagaat gatgacatca agagcagaat atcgactata
    16441 tttaagacaa gataatgcag atatgagatt aactcaaaaa ggttatgata taggattagt
    16501 taaaaaagat agatatgaaa ggtttctaaa taaaaaggct gctgtagaga aagaatttga
    16561 aagactaaaa aatgaaagag ttacaccaaa agaagtaaat agtttgttag aagaaaaagg
    16621 agcaacacca ataaaggttg gaatatctct atatgaattt ttaaagagac cagaggttac
    16681 ttacgaattg cttgaagaat tagggaaagg cgctggagat gatgtttcaa gagaagttaa
    16741 agaacagtgt gtaataataa ctaaatatga aggttatata gagaaacaat tgaaacaaat
    16801 agaccaattt aaaaaacttg agaataaaaa gctggatgag aaaataaatt attcatctat
    16861 agaaggtctt agattagagg ctagacagaa actagatgat ataaaaccta tttcaatagg
    16921 gcaagcatct cgtatatctg gtgtttctcc agctgatata tcagttttac ttatatacct
    16981 agaacaaatc agaagaacta gaggtggcaa aggtgaataa tatagaactt ctgaaaaacg
    17041 ggattgaagg ttttaatata gatacgaatg acagtatgtt agaaaaattt aaaatctata
    17101 gagagatatt agttgactgg aataaaaaga tgaatcttac tggaatagaa gatgaaaaag
    17161 aagtgtatat aaaacatttt ttagactcta tttcagctgt aaagaatgga tatataaaaa
    17221 atgggatgtc tataatagat gttggtacag gtgctggttt tcctggaata ccattgaaaa
    17281 tatgtttaga tagcttagaa cttactttgt tagattcgtt aaataaaaga ataaactttt
    17341 tagaggaagt tagtagagta ctagagttag ataatattac atttatacat ggaagagctg
    17401 aagattttgg taaaaatgaa gactataggg aaaaatatga tgttgctacg gcaagagctg
    17461 ttgctggatt accgattctt atggaatttt gtgtaccatt tgtaaaagtt ggagggtatt
    17521 ttatttgctt aaaaggtccg aatgctaatt tagagctaga agaatcacaa aaggctattg
    17581 atgttttagg attggagtat attgaaaaaa tagatgtaga gttaccagag gtagatttaa
    17641 atcataatat attagttttt aaaaaagtga tggaaacacc agttaagtac cctagaaaag
    17701 ctggtaaacc agccaaaaat cctattaagt aatgaaaaat ttattattgg taagcttaat
    17761 tatttctcag gaaataatta agcttactgt aaaaaaacaa aaataaagga attattaaag
    17821 tagatgcaga aataaatttg tatgtacata tagagaacaa aaataattta tatctaaaat
    17881 aagagaggta tgttatggaa gataaaagag ttatggagat acctatagaa gatgtagttc
    17941 caaatccata tcaaccaaga aaaatatttt cacaagtttc attggaggaa ttgagcaatt
    18001 ctataaaggt atatggtata attcaaccta taacagttag agcaaaagat ggcaaatatg
    18061 aactaattgc aggagaaaga agattaagag cagctaaatt agcagaactt aaaaccatac
    18121 cagcaattat aaataatatg aacgatgaat cttctgctgt tctagcgtta ttagaaaatt
    18181 tgcaacgaga agacttaaat ttcattgaag aagcaattgg ttatgaaaac ttaataaaag
    18241 aacatgcttt tactcaacag caattagcag aaaaattggg caaaaatcaa tctactgtag
    18301 caaataagct tagaatatta aagcttccaa acgatataaa aatgaagcta atagagaata
    18361 atttaacaga aagacatgct agagcatttc ttaaactacc aagtgaagat ttaatgcaaa
    18421 gtgtgttaga caaagtcata aaaaatgaat tgactgttaa aaaaacagaa aaattgatac
    18481 aagatgtatt agaagaaact aaagttcaag aagagcctga taaaaaacag aatataaagg
    18541 gtgctatgag tataagaatt tacataaata ctataaagca ggcctttgat gctatatcaa
    18601 atacaggaat tgatgctaag tataatgaaa tagataaggg agattatatg gaagttgttg
    18661 taaaaatccc taaaaaatag agattactgc ttaccagtaa tctttttttg taatataagc
    18721 cttgtaatat aaactgattt atagacatta tttatactta aaaaacacct attcaacatt
    18781 taaaattaat ttaattctta aaggggggaa catcatgggc aaagttatag ctgtattcaa
    18841 tcaaaagggt ggagtcggga aaactacaac aaatgtaaat ttaagtgcta gcttaggaac
    18901 tttgggaaag aaaatattag tattagattt agacccacaa ggaaatacaa ctagtggata
    18961 tggtattaat aaaaacgaag tagaaaatac aatctatgaa attatgttag atgggttaca
    19021 tattaaagaa gcaataataa gtactgaatt tgagaatata gatgtagttc catcagctac
    19081 tgaactatca ggtgcagaga tagagcttac atctaaaact aatagagagt atattttaaa
    19141 aaattccata aaagcggtaa tagatgaata tgattatata tttttagatt gtccaccctc
    19201 actggggatg cttacaataa attgtttaac tgctgtagat agtgttttaa ttccaataca
    19261 atgtgaatat tatgctttag aaggtgttag tcaattaatg gagactataa aattagtaaa
    19321 atcaagatta aatgctgata tagaaattca aggtgttgtt ttaagtatgt ttgatggaag
    19381 agctaattta tcaatacaag tagttgaaga agttaagaaa tactttaaag gtagtgtata
    19441 tacaacttta attccaagaa atgtaagact tgcagaagct ccaagtcatg gaaaacctgt
    19501 aatttattat gataaaagat gtagagggtc tgtagcttat ttggagctag cagaagaatt
    19561 tatagattta gaagaggagg aatggtagta tggagaataa gtctaaaaga agtaatagat
    19621 taggtagagg tcttagtgca ttgataccag aaattaaagg agaaacttca gaaaaagaaa
    19681 tagtcaacat agatatagac aaaatatatc caaacgaagt tcaacctaga aagcaatttg
    19741 atgaagaaaa gataaaagta ttgtctgact ctataaaaaa ttatggtgtt ttacagccaa
    19801 tagtggttaa aatggatgaa aataataaat atatgataat agctggagaa agaagattta
    19861 gagcatcaaa acttgcaaat aaaaatcaaa tacctgctat aattaaagat atagatatga
    19921 aagatataat ggagatagcc ttaattgaaa acttacagag ggaagattta aattcaatag
    19981 aagaggctct agcatataag agtttaatag agcattacaa tgtaactcag gaagaaatat
    20041 cagaagctgt tgggaagagt agacctcata taactaatac actaagactt ttaaatcttg
    20101 gacaagatgt tatagaaatg atagacagtg gtagaattac agcaggccat ggtaaggctt
    20161 tattgagaat tgcagataaa gatttgcaac ttcaaatagc gaaaaaaata gaagaagaag
    20221 aactttctgt aagagaagtc gaaaatatag ctaaaaaaat atctgaaaat aaacaagaag
    20281 aacctaaaaa atctaaacct aaggatgtat ttattttaga tgttgaagat aaacttagaa
    20341 atatatttgg aacaaaggtg aatatttcta aaggaaagaa aaaaggtaaa atagagatag
    20401 aatactataa tgatgatgat ttaaatagta ttgtatcaat gcttcttgaa tagaacaaaa
    20461 atataaaaca gagaggaaga ttgttatgat ttatttagat aatgctgcaa ctacatatcc
    20521 aaaaccagaa agagtgtata atgctgtttt agattgtatg aaaaattatt gtgcaaatcc
    20581 aggtagagcc ggccataaac ttgctatgag agctgctagg gagatatatg atacaagaga
    20641 gaatatagct aagttgttca atgtaagtaa tcctatgaat atagtattta catctaatgc
    20701 aacagattct ttaaatttag cgataaaagg tgtattacaa gaaggagacc atgtaataac
    20761 aacgtctatg gagcataatt cagtaataag acctataaaa gcattggaaa aaaggggtat
    20821 tgaaaatact gtagtaaaat gcgattatga gggattttta gattatgaag atttagaaaa
    20881 atcaataaag aataatacta aattgattgt aacaacacat gcgtctaatg tatgtggaac
    20941 tttaatagat ataaaaaaag ttggagaaat agctaaaaaa cataatatac tatttttagt
    21001 agatgcatca caaacagcag gtgtttatga tatagacgta aatgaatgta atatagatat
    21061 gttggcaatg ccaggtcata aatgcttatt tggacctcaa ggaacaggta tattatatgt
    21121 aagagaaggg ttgaacttaa atatattaaa agaaggtgga acaggtagta aatcagaaga
    21181 aatagttcaa ccagagttat tcccagataa atatgaatca ggaactcata atactccagg
    21241 tatagcaggt cttaaccaag gtatactatt tatatttgaa agaggaatca acaatataag
    21301 acaacatgaa gaagaattat gtcaatatat gatagacaaa ttagaggaag taccagatat
    21361 aaagatatat ggaccaaagg acagtaaaaa aagagcatca gtaatagctc taaatatagg
    21421 agatatggat tctggagagg ttactttctt attagatagt gattataata tagcgactag
    21481 atcaggaata cattgttcac cactagcaca taccacttta ggtactttaa aacaaggtgc
    21541 agtaaggttc agtataggat atttcaacac aaaagatgag atagataaag cagtggaagc
    21601 tttgaaaaaa atttcaaaaa ataaatagca tgagatttaa taatatagaa ataaaaaaag
    21661 gggatatttc aaaataaaaa tttgaatcat ctcctttttt gtacaaaaaa gaaaaggggt
    21721 tcctaagaac ctctaatcta tttgataata gtttcaagaa attactttaa gtaatctcct
    21781 tcttcaagaa ctatatgacc actttcgtaa ttagaaccat caacagtaat ttttatttgt
    21841 tcaacattca tattttttat gtaagtacga gcaactgaat caagcattaa agtttctgca
    21901 tcactaccta agtttgactt tgtaaagtca gagctaacat ctaatatacc agtttttaca
    21961 ccatcaatgt cttttgtagt aaatgaattt aattttgcag attctggaac aactttaagt
    22021 ttttgaagtt cttcaaataa agtgttctca tcaattttat ttaaatcaac tttattttca
    22081 attaaatctg tcttatctac atcaaaagag taaatagtag ctgattgagc tttagtttct
    22141 tcttttggag taggtttagc tttgttatta ggaacctctt tttcagtatt gttttcttct
    22201 tttggttgct caacatttgt attgctctta gtttcttttt tagatgaatc acttccattt
    22261 tgagcattag tacaaccaac tgcgaatata gatatagata atatacttaa cactaacatt
    22321 attttcttat ttttcataaa aatttctcct ctcttaaaaa ctattcttat atataattat
    22381 agtcgttatg agcaaatata tgaatacaaa atagtaacaa atttaaaaaa tgatttattt
    22441 aaattaataa aactcaaaat aaactaaatt ttagtcattt ttatgggaaa tcatttaatg
    22501 tacagtgaaa atattgtaaa ataaaagtag tgtttttaaa ataaatataa gttataatta
    22561 tattataaaa aaatgtcttc aaaaggtggg aatagtatgg aaattttgag cttaggagaa
    22621 aagattaaaa agttaagaaa agaaaaaaac atgacattga aagaattagc tggagatagg
    22681 ataacagcag cacaaataag ccatatagag agagataaat ctcatactag ttatgaactg
    22741 ttggaatatc taggcgataa gctagatgta agtgtagaat acttattaga gaccaaggaa
    22801 atgcaatcaa aaaagataac tgataattta atactacaga gcgaaattta tataaaagaa
    22861 aatgaattaa acaaggctga ggaccaaata aaagaagttt tagatatatg taagagatac
    22921 gatttaatgg agaactatgg cagatgtaat tttttaatgg ctaatattaa tttgaaaaaa
    22981 tctaattata atgatgctat agaaaacttt gaaaaggcat tgtacttctt tataaaaaat
    23041 agtgatagtg aaaatatact taagtgttat ttaaacatag ggaaaatata tatgcaggaa
    23101 gacttttata aaggtgctat aagccacttt aattttgcag aggaaatttt gtcagagagt
    23161 aaatttgagg atgttaacat acacaaggaa ctatatagta agatggcata ttgttacata
    23221 aaactagata atccaaatat gtcattgaag tacatagaaa agataaatga aatagataat
    23281 agaaatgata gaaaagaaga tgtcgatatt ttggtgttaa aagcaaataa tatgcttgag
    23341 attggaaaat atgaagaatc aagagattac tttaaaaaag cactaaaaat acttgagagt
    23401 gaggataata aaactggatt agcaaatgtg tatttaacaa tttgtgatgt ttacagaaaa
    23461 ataggtgaaa cagatagagt acttgaatat tcacaaaagg tatatgacat aaagaaaaat
    23521 gatgaagatg aatacatgat gtcaggatta tttaagataa tagaagcata tatagataaa
    23581 gaagattatg atttagctag aaaatattgt aagatagcct tagcttcatc aataaaaaat
    23641 aaaaataaat tcaatgaata taaagcattg agattctatg ctaatatgta taaaaatcag
    23701 aatgaagtaa ctcttgcaat tgaatatctg attaaatgca taaaaatagt atcagattta
    23761 ggcaacaata gaatattggc caatttatat atagacttag gtcaattata ttcaaatata
    23821 tcaaaagaaa aagagttaga atattatcaa aaaggtgtat ttatgtacaa aaacttagaa
    23881 ataatgtagg gtaaataaac ctataagggt atagaaacaa tctataacaa gcaagataat
    23941 atctatgata aaatataaat tgtatgaata tttttaagga gatgaatcag acaatgagta
    24001 taaaaataga tgcgagaggg cttgcttgtc ctaaaccagt tataaataca aaaagagaat
    24061 tggataacct agaagaaggt gttgtagtta caatagttga taatgaaaca gctaaggaga
    24121 atatattaaa acttgctaaa tctttaagtt gtgaagcaaa tattgttgac gaaaaagaga
    24181 attttatatc tatagaaatt agaaaaggta aaaatatact agataaacaa aatgttgtag
    24241 ataataaaga aagtgaatta gacaatacat gtatatttat atcttcagat aagatgggac
    24301 ttggaaatga cgaattagga aaagtgttaa taaaaggatt tatatataca ttaacagaat
    24361 ctaaacctta tcctaagtat gtacttttag ttaatggagg agtaaaatta agtgctgaaa
    24421 atgaagaaac catagaaaat ctaaaaatac ttgagaatat gggtgtagaa gttttatctt
    24481 gtggtacttg tttagattat tataatttaa aagacaaatt acaagtaggt acagttacaa
    24541 atatgtatac tatagttgag acattaaaga atgcatcaaa taccatttct atataatgta
    24601 tgtatgttta ataatataaa actaacaata aagattaact caaatagata gtcagaaagg
    24661 attaagtaat gaatcaaatg tatatagtgt catttaattc gacacatcat gcgataagat
    24721 cagaaaagtt atttggtgaa aatagtctaa aagtaatggc tcttccaaca ccaagagaaa
    24781 taacagcaag ttgtggaata tcaattaaat tttcttttga agatatggaa aagataaaaa
    24841 ctattttggt tgaaaataat gtagatataa aaggaattta ttgtataagt aaattagaaa
    24901 atggttcaaa agaagtagag aagttagatt aggaggctaa ttatttatgc caatggattt
    24961 aaaaataggt gatattgttg aattaaaaaa gcaacatgca tgtgggtgta aagagtttga
    25021 aatcataaga acgggaatgg atataaagat aaaatgtact agatgttcaa ggctaataat
    25081 gcttgataga gagaccttag aaaagagagt aaaaaagcta ataaaaaagt gataaaaatt
    25141 taacacttaa aaaatgtcaa ataccgtata ttaatatcca aaattttggt ataataagaa
    25201 ttgaagaaaa cattttcatg ggggtgcttt aattatggca gttaaatatg caaaaagaat
    25261 gcaaggatta caaggatcag aaatacgtga gcttttaaaa cttactcaac aaccacaaat
    25321 aatatctttt gctggtggaa tgccggctcc agagttattt ccagttgagg aaatgaaaaa
    25381 agtatcagtt gcagtgcttg aagaaaatgg aagatcagct atgcaatata ctacaacaga
    25441 aggatatgaa ccattaagag aaaaaatagc agctagaatg aatgataaaa acaaaactaa
    25501 tgtaaacaaa gatgatatat tagttacaag tggttctcaa caaggtctag attttgcagg
    25561 aaaagtattt attgatgagg gtgatgtaat tttatgtgaa agtccatctt acataggagc
    25621 tataaacgca tttaaatctt atcaacctaa attcatagat gttccaacag attctgatgg
    25681 aatgataatg gaagaattag aaaagatact agaaacaact gatagaataa aaatgattta
    25741 cgtaatacct gacttccaaa atccaacagg aagaacttgg ccacttgaaa gacgtaaaaa
    25801 attcatggaa atagtaaata aatttgaaat accagtaata gaagataatc catatggaga
    25861 tttaagattt gaaggagaga ctttaccatc tttaaaatca atggatacaa aaggattagt
    25921 aatattctta ggaactttct ctaaaatatt ctgcccagga tacagattag gatggacttg
    25981 tgcttctcca gaaattttat ctaagtttaa ctttgcaaaa caaggtgcag acttacaagc
    26041 atcaactata tctcaaatgg aagtaagcaa atttatggat atgtatgacc tagatgcaca
    26101 tgttgacaaa ataaaagcag tttatgttaa acgtagagat gtaatgctta agactatgga
    26161 agaagagttc ccagaaggat tagtatttac tcatccagaa ggtggattat ttacatgggt
    26221 agagcttcca agtaatttaa atgctaaaga attaatgcca aaatgtttag ataagaatgt
    26281 tgcttatgtt gctggaggag gattcttccc taatggtggt agagaaaata ctttcagact
    26341 taactattca aatatgccag aagaaaaaat aatagaaggt ataaaaaata tagcagctgt
    26401 attaaaagaa gctatgggtg tagaagctta attaaaaata ataacttata tataatacaa
    26461 gggatggttg ttgccatccc ttgtttgttt gaaaagtata taattcacct tatactaaac
    26521 tttgtccaaa atttaaattg acagaaataa gaataaatga taaaatgtgt aggtatgaga
    26581 ttttagtctc atttctctgc tctaagagtg tagagccgtt aagtccaaag ggaggtgaat
    26641 tatagtgaga aattatgaat tagtttatgt ggtaaagcca aactctgatg aagaagtaag
    26701 agaggctata ctaaacaaag ttaaggaagt tgttgcaact gacggagaaa tagttaaagt
    26761 tgatacttgg ggaactaaaa aattagctta tccaatagct aagtttacag aaggtttcta
    26821 tgtattagtt aacttcaaat cagcagtaga cgttcctaaa gagatagaca gaaacttaaa
    26881 gataaatgaa aacgtaataa gacacatgat agttgttgct taataactgg ttttattata
    26941 aaaaataggt ggtgttttta tgaataaagt tgtattagtg ggaaggttga ctagagaccc
    27001 tgaattaaga tacatcccag gtacaggaac accagtggca tcctttacaa tagccattga
    27061 tagagactat gtaaaaaaag atggatctaa agaaactgat tttatacctg ttgaagtaat
    27121 gggtaaatct gctgaatttt gtgctaacta cataactaaa ggtagattag tagcacttca
    27181 aggatctata agagtagaca attatcagac acaatcaggt gaaaagagaa cttttacaaa
    27241 agtaagtact agatcagtac aagctttgga tagtaagaat aaatcggaaa attcatatag
    27301 agagagtgct ccagcttttg agccaagctt tgaacctcaa ggtttagacc cacaaggttt
    27361 ccaagctata gatgatgacg atataccatt ttaaaaagga gggaaaaaag tcatgatgaa
    27421 taaaaaaaga cgtaagaaaa aaagagtttg tcaattttgt gctgacaaaa acgctaaaat
    27481 agattacaaa agtactcaaa gattacaaaa gtatataact gaaagaggaa agatattacc
    27541 aagaagaata tctggaactt gtgctaagca tcaaagagaa ttaacagttg ctataaaaag
    27601 agcgagaaat atagcacttt taccatatac attagactaa aaaaatgagc cttgtgctca
    27661 ttttttatta tatgtattta tatatctaaa tgaggcgagc tataaagctc gtttttttgt
    27721 ttatatactt aaatatatta ttatttatga tataatatta tatattaagg agggttgtaa
    27781 acgtgaaaat agataaaggt tctgagataa cgagaaacat aaagataata gaatggatga
    27841 aaacagaaat attaatgagt gtaagtgatt tgtttaattt attgtttaaa ggggtaaaac
    27901 cattagatga agcaattcaa gatactttag caaatataat aatgataaca tatctcttag
    27961 caaagagatt aggaattagt tttagagatg tggattataa agtcaaggaa aaaataaaaa
    28021 ttggtataga tgaggaccat agcgttgaaa gatggtatgg ggatttatct aatttaaaaa
    28081 aacatatgga taatagggag tgatattaaa ttgaataata aaattagact atctaaggca
    28141 atgtctataa tagttttagc tataataatc gctttagtaa tagcctatat tccaatgcta
    28201 ggaatattta gtatgttagc agctgttcca tatgtaatta taggtgctat tactgataga
    28261 aagtattctc ttatatctat tttggttaca ttttgcgtac tgattctatt tgcagatatt
    28321 tcttacgcat taaatatatg tataatgtat tctttaccag gtatagtaat aggaaagatg
    28381 ctaaagagaa gctttgaaca agaggacagt aataaattcg aaccgatata tggtggaacc
    28441 ataatatttg tactttcaat gcttgtatat ttttttgtat taaagacatt tttaaatgtg
    28501 aatctattag atgaagtttc taagatgata tcagaaattg taaatattca aaaaaatagt
    28561 ttttctgcaa ctgaacttaa agtgtttgat aaaatgaagc cagatgagat tgtaagttat
    28621 tttacaaata tgctaccaat gatgttattt ttacaagggt tgttatcagc gtttgtcaca
    28681 tattatttga gtgtattttt tataaaaagg attacaaaga tgaatataag atttcctaag
    28741 tttgctgatt tttatttacc gggaaatgct atactcacaa ctttcttact ttatttatta
    28801 gtcttattta ttcaaattat tggttcaaaa ttatatacag aattaataat gactaattta
    28861 cagctagttt ttaatttaat gtttgtaatt caaggtatag cagtttgcat ttatttctta
    28921 aagaaatgga taagacaggg accaaataaa attatgtttt tttcagggat aattttatgt
    28981 ttatttggat ttatgggaat atcttttgtt ggtatggtag atagtataat tgactttaga
    29041 aaggtaagaa gctataaatc cacttaggag gatagaaatg agtaataaac aagcctttaa
    29101 attaaatatg ccagaaataa atttatatat aattgttatt ggtatttcta gtataatttt
    29161 gctttattac aacttgtatg tagggtgttt atttttctgt atttttgtat atatggtttt
    29221 tcacaattgg agaactacta atattagacg tcatgaatgg acagagtata ttcaaaattt
    29281 atctttagat atagatgaaa caactaaaaa agccataata aatcttccaa taccattatg
    29341 tattttagaa tttgatggaa atatatcctg gtataatgga aagttttatg atatgattgg
    29401 tcaaaaagat ttacttgata aaaatataga ggatatagtt aaaaatctta atttaagaaa
    29461 agtattaaat gaaaataaag agatgtacac agaaataaac tataaagaaa aagaatatac
    29521 aataatttat aatgttataa aaaatgatca agaaaaaaat cctaaatatt tgatgatatt
    29581 atactggata gacaagactg aatatttaaa agtaaaacaa aattatgatg atgaaaaaaa
    29641 tgcaatgatg ctaatacaag tagatggata tgatgaagta ttaaaaagtg cagcagaaga
    29701 taagagagct ttaattaatg ttgaagtaga gaaaatactt tctgctttag aattaaattc
    29761 aaatggtgca ttgagaagaa cttcaaaaga caaattcttc ttggtaatgc ataaaaaaga
    29821 gttaaaaaaa ttggaagctg agaagttttc tattttagat acaataagac atattgatta
    29881 tggaaataat cttcctgtta ctataagtat aggaattggt atagatggag atacattaaa
    29941 tgagaaccta aaacttgcta cgggtgctct cgatttagca cttggtagag gtggtgacca
    30001 ggctgttgta aaaacaaaag ataaatttgt gttttatgga ggaaaatcta aagctgtaga
    30061 aaagaaaacc aaagtaaaat ccagattaat aggtcatgct ttaagagagg ttatacaaca
    30121 aagtgaccag gtttatataa tgggacataa atatcctgat atggatgcta tgggagcagc
    30181 agttggtgtt tatgatatat gtaaatcctg taacaaaact gcaaacatag ttttacaatc
    30241 tgtaaatgaa tctatagaaa tatttataaa taaaataaat gaaaataatt actataaaaa
    30301 gttgtttatt ggaaaagagg aagctattga caactgcact aaaaatacat tagttgtagt
    30361 agttgatact catagaccaa attatactga atgtgaagaa ctgttaaagc tatcagagaa
    30421 ggtagtagtt atagaccatc atagaagagg tgtagagttt ataaatgatg cagtgctttt
    30481 attccatgag atatatgtat cctcaacgtg tgaaatggtt acagagttag ttcagtatat
    30541 ggatgaagat gtaacaataa ataaacttac agctgaaggg cttttagcag gtataagtct
    30601 agatactaaa aactttgcat tcaaaacagg tgttagaact tttgaagctg cttcttacct
    30661 tagaaaagtt ggagcagata ctatagaggt aaagaaattc ttcaattctg atgtaaaaga
    30721 tttcataata aaagctgaaa taattcaaag tactaaaata attaataata gaatatgttt
    30781 agcatattca agtactgaga tagatagtat aaatgttata atagctcaaa ctgctgatga
    30841 gttattaaat atcaaagaag tagaagcttc ctttgtatta ggtgaaaaag atgatactat
    30901 atttataagt gcgaggtctt taggacaaat aaatgtacat gtacttatgg aaaaattagg
    30961 aggcggggga cacatagata tagctggagc acagttaaaa aatgtttctc taaaagaagc
    31021 ttataagatg gtaaataaaa taatagagga gtatttggag gaggaagaat agatgaaagt
    31081 tatattatta aaagacgtaa agggaactgg taaaaaggga gaaatgaaag aagtaagtga
    31141 tggatatgca agaaatttct tatttcctaa aaagatggct gtgcaagcag atagtgtagc
    31201 aataaaagaa ttaaatgaaa agaataaatc taaagaaata aaagcacaaa aagagtatga
    31261 agaagcagtt ttattaggta agcaaatgga agaaattaat atagaaatat attcaaaagc
    31321 aggagaaggt ggaagattat ttggttcaat aacttctaaa gaaattgctg agcaattaaa
    31381 gaaacaaaaa gacatagatg tagataaaag aaaaatatta ttagatgaac caataagatc
    31441 tttaggttca actttcgtag aaataaaaat acatcaaaaa gtaactacta aaataagagt
    31501 ggatgtaaaa gaaaaacagt aataactaga ggtgattaag atggaagata tgacgagaat
    31561 tcctcctcat agtgtagaat cagaacaatc aatattgggt tctatacttc tagataaaga
    31621 tgctataata acggttacag aaactataaa gcctgatgat ttctataaag aggctcacaa
    31681 aataatatat gaatgtatga taactttaag taataaaggt gagcctatag acttgataac
    31741 attaacagaa gaactaagaa aacaagggca tcttaatgat attggaggaa tcagttatat
    31801 tacaagtctt tctactatag taccgacgac ttcaaatgta aaatactatg ctgatatagt
    31861 aaaagaaaag tctgtactta gaaagcttat aaaagcttct aatgaaataa taaatctagg
    31921 atatagtgga gcaactaaga ttgaagatgt tttagaacaa gctgaaaaga gtatatttga
    31981 tatatcacag gagaaaacta gtgatgattt taaatctata aacttagttt tgatggatgc
    32041 ctatgatatg atagaaaaat tatacactaa caagagtgat gtcactggta taactactgg
    32101 ttttaaagat ttaaacaaaa aaataaatgg tcttcaaagg actgatttaa tattaattgc
    32161 agctagacca gcaatgggta aaactgcctt ttctttaaac ttggttcaaa atgcagcctt
    32221 aaaaggtgat gcctctgtag ctgtatttag tttagagatg tctaaggaac aattagtaca
    32281 acgtatgtta tcttcacaat ctagtgtaga attaaaaaaa ataaagactg gaacacttaa
    32341 tgataatgat tggcctagaa ttatagatgc tatggcagta ttatcagatg ccaaaataca
    32401 catagatgat actcctggta taaaaatatc agaactaagg tcaaagtgta gaaagttaaa
    32461 aatagaaaaa ggactagatt tagtgcttat tgattatctt caacttatgg aaggtgaagg
    32521 taataatgaa agcagacaac aagagatatc taagatatca aggtcactaa aaatattagc
    32581 aaaagaatta aactgtcctg tagtagcact atctcagtta tcacgtgcac cagaacaaag
    32641 agcagaccat agacctatgt tatctgattt aagagagtct ggagcaatag aacaggatgc
    32701 agatatagtt atgttcttat acagggacga atattatcat gctgattctg agagtaaaaa
    32761 tataggagaa gtaataatag caaaaaatag acacggtgaa actggttctg tggaacttgt
    32821 ttggcttggt gaagttcaaa gatttgggga taagttgaga gacctataat ctaacgaata
    32881 tccacagaac gtcctttctt tctacaggaa aaatgtggat acatgtcact aaatatgtcc
    32941 aaacattgaa atttagctaa aaaactatcc acactatcca cagatggcct gttgataagt
    33001 gtgaataagt agataaagca agcttttggc ttgctttatc tgtgtataaa tattaattat
    33061 taggaggaat aatatggaaa aaataagctt aaaatatata tatcccaata taattaaagt
    33121 acttgatgaa ataaacttat ttagagtaat tgacaataat ttaagagaat ctattgttgt
    33181 ttatgctaat aatgtggata atcagtatca tataaacatg actaatacaa actttggaaa
    33241 cataattaac atatgtaaat tagaaaaact tttagatgtg gataaattta tggaaaaagt
    33301 tataaaatat gaaaaagaaa taatagagaa agaagagttt tcaaaaatag aagaatatat
    33361 gttaaatatt ggagaatact aaaaaagttg aaaaaaatac gaatgtttga tagaataagt
    33421 aagtaaagtg ttcgagagta tataaaatat agaggtgaat tacatgaaaa cagttgcaat
    33481 tgttggttct caatggggag atgaaggtaa aggtaaagtt atagattatc ttgctactca
    33541 agcagatgta gtagtaagag ggcaaggtgg aaataatgca ggacatacat tagttgtaga
    33601 aggtaaaaaa tacgcattac atctaattcc atctggagtt ttaaatccaa atacagtgaa
    33661 tataatcgga aatggaatag tgtttgaccc taaaggattt ttagaagaat tggaaatgtt
    33721 taaaacggat aatataagta cagaaaatat aaaaataagt gatagagcac atgtcatatt
    33781 cccatatcat aaagaactag atgcattgtc agaagaagcc agaggcgatt taaagatagg
    33841 tacaacaaaa aaaggtattg gaccttgtta tatggataaa acagagagat ctggtattag
    33901 aatatgtgac ttaatggata aagataaatt tgctataaaa ttaaaagctc aaatagatgc
    33961 taaaaatgaa atagttaaaa atatatatgg aaaagaagaa ctatttgatt ttgaaactat
    34021 atataacgaa tatctaggat atgcagaaca aataagaaaa tatgtggcag atacgtctgt
    34081 tattgtatat gatgcagtaa gagcaggtaa aaaagtattg tttgaaggag cacaagggac
    34141 tttattagat ttagatttag gaacttatcc atttgttaca tcttctcatc caacatctgg
    34201 tggatttgca attggtgcag gtataggacc aaatatgata aaagacgttg ttggtatagt
    34261 aaaagcatat actacaagag ttggagaagg accgtttgtt acagagcaaa taaatgaaac
    34321 tggagataag ataagagaac aaggacatga atttggggta actactggta gaccaagaag
    34381 atgtgggtgg tttgatgcag ttatagttaa gtatgcagct agagttaatg gattgactag
    34441 tatttcattt atgttacttg atgtattaac tggatttgat aagataaaag tttgtacgtc
    34501 ttataaaatg ggcgataaga taataacgga tttcccagct tcattagatg atttagcaaa
    34561 atgtgaacct gtatatgaag aattagatgg atggaatgaa gatataactc aaatagataa
    34621 ctttgatgac cttccagaga atgcaaagaa atatgtagca aaaatagaag agctagttgg
    34681 agtaagtgta gatatggttt ctgttggtcc aaatagagct caaactataa taagaagaaa
    34741 tatatttgct taatatttta tcaattaaat aatttaaaat agttgaagaa gagtatctca
    34801 agataatgtt tatagttatt agagatgctc ttttatattt gacctacatt gattttttat
    34861 taagttaaag ctacttatac atattctaac tgaaattaaa gttgaattta tgtagataca
    34921 tataggtttt ttaaaaagaa ttttgttgaa aataaatggc taaagatgat tttaattata
    34981 ttctaaaaaa agtaaaaaaa actattgact aaaaattata tagacgctat aatataactt
    35041 gtgagtgaaa gaaacgacga aaaaagtcga aaaaat
//
LOCUS       DAEOTL010000040        34195 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEOTL010000040 DAEOTL010000000
VERSION     DAEOTL010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.040"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            32..1144
                     /locus_tag="KRH82_002229"
     CDS             32..1144
                     /locus_tag="KRH82_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBG8655508.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKIKNNKSTLSIILSIFKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENL
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLIFSLLYVLFWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KRH82_002230"
     CDS             1398..3422
                     /locus_tag="KRH82_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8655509.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KRH82_002231"
     CDS             3642..4328
                     /locus_tag="KRH82_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBG8655510.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KRH82_002232"
     CDS             4423..5478
                     /locus_tag="KRH82_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBG8655511.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KRH82_002233"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KRH82_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBG8655512.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KRH82_002234"
     CDS             7195..8901
                     /locus_tag="KRH82_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBG8655513.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFKEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDSVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KRH82_002235"
     CDS             8923..9996
                     /locus_tag="KRH82_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBG8655514.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KRH82_002236"
     CDS             10008..10730
                     /locus_tag="KRH82_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBG8655515.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDLNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="KRH82_002237"
     CDS             10746..11903
                     /locus_tag="KRH82_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBG8655516.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGKVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="KRH82_002238"
     CDS             11906..12745
                     /locus_tag="KRH82_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8655517.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="KRH82_002239"
     CDS             12760..13935
                     /locus_tag="KRH82_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBG8655518.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="KRH82_002240"
     CDS             13964..14713
                     /locus_tag="KRH82_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8655519.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="KRH82_002241"
     CDS             14735..15643
                     /locus_tag="KRH82_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8655520.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="KRH82_002242"
     CDS             15691..16443
                     /locus_tag="KRH82_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8655521.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="KRH82_002243"
     CDS             16397..17764
                     /locus_tag="KRH82_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBG8655522.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="KRH82_002244"
     CDS             17770..18861
                     /locus_tag="KRH82_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBG8655523.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="KRH82_002245"
     CDS             18945..20858
                     /locus_tag="KRH82_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBG8655524.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKDIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="KRH82_002246"
     CDS             21057..21764
                     /locus_tag="KRH82_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8655525.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="KRH82_002247"
     CDS             22066..24177
                     /locus_tag="KRH82_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBG8655526.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="KRH82_002248"
     CDS             complement(24375..25340)
                     /locus_tag="KRH82_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBG8655527.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="KRH82_002249"
     CDS             complement(25625..26581)
                     /locus_tag="KRH82_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBG8655528.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="KRH82_002250"
     CDS             26949..27737
                     /locus_tag="KRH82_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8655529.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="KRH82_002251"
     CDS             complement(27860..28330)
                     /locus_tag="KRH82_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBG8655530.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="KRH82_002252"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="KRH82_002252"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBG8655531.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="KRH82_002253"
     CDS             29156..30061
                     /locus_tag="KRH82_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8655532.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="KRH82_002254"
     CDS             30376..31923
                     /locus_tag="KRH82_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8655533.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="KRH82_002255"
     CDS             31926..32324
                     /locus_tag="KRH82_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBG8655534.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="KRH82_002256"
     CDS             32364..34097
                     /locus_tag="KRH82_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBG8655535.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNITQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
BASE COUNT        13658 a         3607 c         6016 g        10914 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaagataaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gtactgctac aataattact tttctatgta tatctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccag aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa atctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgaaata ttaagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 gatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaagatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacgcaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccatagtaca aacttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gccatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagagtt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaacct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtccat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagatttta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt aaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ttatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatagtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcgacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtact atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgacctaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcggca tgttttttaa
    11101 tggtagctat attattattt aatctatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaataattt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccga
    11461 taatacttac tttatttagt gtaattattg gtaaagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggcatgtata cttggctgaa aaggggaact
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgagaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaggtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggctca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagaacttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagatact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatatgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgattct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aaacataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taaaaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag atattattga tatatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcttaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgcaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaaaacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttgta tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaaa aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaggaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aatcatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggataattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatccagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga taatgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtagat
    24001 gcattaacat caggtccttt agcagctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta taaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctgtgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc acccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ttccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat ccaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaaataat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtgctat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca cgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagtattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactaatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atcttataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagatgaag
    27301 cgtttataca agaggtcagt acttattatg caaagtttaa aattgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tatttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat atctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatcgc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtaac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactaatcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 agttaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgga aatattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 gatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaatcttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgac
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata cagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtaaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataactcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat agtagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataacaat ttttcaagtg
    33781 cagatgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttagag
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttt
//
LOCUS       DAEOTL010000041        30893 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEOTL010000041 DAEOTL010000000
VERSION     DAEOTL010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30893
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.041"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            280..735
                     /gene="smpB"
                     /locus_tag="KRH82_002257"
     CDS             280..735
                     /gene="smpB"
                     /locus_tag="KRH82_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBG8655536.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
     gene            893..1242
                     /gene="ssrA"
                     /locus_tag="KRH82_002258"
     tmRNA           893..1242
                     /gene="ssrA"
                     /locus_tag="KRH82_002258"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1908..3167)
                     /locus_tag="KRH82_002259"
     CDS             complement(1908..3167)
                     /locus_tag="KRH82_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBG8655537.1"
                     /translation="MIECIPYPGYRDRDGYGQINSNKEGTLRAARIVLEERLQRPIRN
                     GYQAHHTCYNRCCVNPSHIEERKVSENILDKYFNDRPEINEIVLTKESVYLTKYLLNN
                     MNNSEFNYSIEEIAKFLSIPLELLLYIKKGSVWNYIYLTNAEKVEALHKLEIFFPKEV
                     CIEANWGSEKYCPVVHKNNKQIKASRYSYDTYTNTSSSGKYILHNCDNPLCIRASHLR
                     TGDQKDNMNDKVQRRRTNRDYYLYNQEIIKKIVQLRDVENYSFSKIGREIAILVKRDK
                     PYDHKTVISIYKNYKYTRREELKEKPPTQRELLNKHIDTLIDLKHNYNYSLRQISHKL
                     GSNLIGKPFDLNVIGQVYKEHISKQNLIPPKSSIKLLEENITEILSMLDCNISLREIA
                     NRLTKKLNPNKPFHHNQITKVVNKYKK"
     gene            complement(3266..4432)
                     /locus_tag="KRH82_002260"
     CDS             complement(3266..4432)
                     /locus_tag="KRH82_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8655538.1"
                     /translation="MATKIANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFKYRIKDLKPKSFERYESIYRNYI
                     KDTDLVNVKLNDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKIEILTLEQQKSFIKAIDGHKLEVLFLLALGTGLRLGELLGLKW
                     FDINFKNSNLTVKRTLQRTYFIDKNGDRELKVLEQEPKTSNSYRTVPIPKNILNKLKE
                     HKVSQNTDILKAGELYRNDNYVFCNKLGVPIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENNVPPKAVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(4422..5174)
                     /locus_tag="KRH82_002261"
     CDS             complement(4422..5174)
                     /locus_tag="KRH82_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBG8655539.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKEKLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEPTLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     GDEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            complement(5266..5756)
                     /locus_tag="KRH82_002262"
                     /pseudo
     CDS             complement(5266..5756)
                     /locus_tag="KRH82_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6007..6771)
                     /locus_tag="KRH82_002263"
     CDS             complement(6007..6771)
                     /locus_tag="KRH82_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655540.1"
                     /translation="MQIGKNLKKIRKQKELTQIQLAEISDISRNALINYENDKRIPNI
                     DTLSKLAKALKIEKTIFYFDIENEVITNEDVLYFLQSLFPEEYYSFDEFLNAISNLME
                     DDDIRITSSLLLGAWSDKDQYYKLGEKLELNENQVYNWILSDCISNTELDFSLHPDDI
                     KEIIKNDVLTKQSIDELLDIGLSEENIETIYDYFSDSTDNGSNIRLKKLISQKENITI
                     KNNDYFKLLQENNELKEKNEKLENTLKEIKKLLTKI"
     gene            6907..7555
                     /locus_tag="KRH82_002264"
                     /pseudo
     CDS             6907..7555
                     /locus_tag="KRH82_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891536.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            8179..11658
                     /locus_tag="KRH82_002265"
     CDS             8179..11658
                     /locus_tag="KRH82_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBG8655541.1"
                     /translation="MGKIEPNQEDRIYEDLYQGNSAEGKVCEWIEEAINDDCYVGQHR
                     FKIETRECDIAMVIPNRGILIIEVKGYTVEMIDHMSSNFIIHVKKEYENERFKTGERH
                     PAEQANDYVFTMMRDFSGFLKRNNICLPICKIGRMAAMPNMTDKEYEELYLDYCYSTK
                     LVITKDWFKNKNIFYHRFINALNIIFNSISSEVDFDDSYYNIARRYILLGERKKYVDL
                     CKEQLKREEELGIDFIIDNTNEEVDQLCKSNEVNDEEMELIKFSSVLQEELTESHKLS
                     KIIPYSKLRIVKTGCEIEPLLEICCNERKEGIKQFLILVNFTRDEKEKILLEYEKRFL
                     NKYKENELLFLFNMYFIDLSNDDTSIDNLFSNHDNIEIINGERIEEIVKIKPDNFIVQ
                     EFTPKDLLDQALWNILCIADNFTSFNFDQYIVEHSPLRQNIVVTASAGTGKTYTMVDR
                     VSFVAHMEIIYRNSKESISDLISMITFTNNSTDEMKERLMKHFMQYFELTHNKVYMDL
                     LEQLGRMKIKTIDSFTKYILSKFAHLLGLSNSFSLKSGKFELENILRKYINDEITKEI
                     IDDFHNINIYEIANHILALRSFLINRKIQFDKIKHASIVGPDVGKGTIRMKNFIESVL
                     ISTNSEYDSFNCSQNFISMNELVIQLEKVKNKLIKTSCVNNTKENYEKYLFIDEFQDT
                     DNKQIQLIRFFADYFNIALFVVGDEKQCIYGFRGAERTSFLELTCVDTNFQQRNWISC
                     FLRKNYRTEEPLVKKINEVFSKMPNDFFPYQNKDKLVAQKGIGRIYSGCYEQFKYSEN
                     NLIELVDNCVKRMKKNNEDGQIAILTRNNYEVDQIRALFGENKEYEIKFDNGGLFYNT
                     DAVIDFYKLVEFLMDTEDGAKRYSILETPYSDFRIKESKIKLYQAYEKMDVETFEIIR
                     SGNNHVSLRKYYDVLYNYGKKHPNLKNSPSLKILRMIVNEIKPWEHYVPERYKTVDFN
                     DICNQNKLIEARNEYRQNLFQLFQKLIDDNKTDYLTLNKIHQILTIGIFAMQDIDIDL
                     PKNNFFGEKISVLCTTVHKSKGLQYHTVIMPFTMNDITESRGSTQFIYREDTNEIYMQ
                     LKEADGKCLIYESTNFDCENNKKNETIQSEELRILYVALTRSKKFFYFMVDEERFEKN
                     NTSKKNCWAHYLM"
     gene            11675..14911
                     /locus_tag="KRH82_002266"
     CDS             11675..14911
                     /locus_tag="KRH82_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655542.1"
                     /translation="MKIYTYKNSVQLKDAIFWNEIEGAPHFCSSEVLAIGMRKFYGRN
                     TFPCISTIDLLIKELYPNWLKSHSDIERYKDISKLINELNDSSTEGLRQAFVKNKKSI
                     LDSCKYLIETEDLLLKDYYNKNIFNKFSAINDIQEVFKEKILKRLLEQIYIDGNKNYW
                     KPEWIDTLWVKSKLSEVIHKCVIKEISDIVKNTEEKSLNHNYDEGHIFEIFDELFDQH
                     GLFNISDKTLEYWKFNSKDDLLDKIGYSSKELEYVRNLATTECKSYKTIVIHGVYHLN
                     PIHLRLLRDLERDHNVIVLNCYNKEFNHIYEFWNDIYDHLIKIFQIPKNNIKIDSHDS
                     ANHREVGSIFAEVVNGVINKQSNFFKISRNEFGPDLNLNSKDIDELFNHNSSQDIRYI
                     LNKSEAIIQNYEDEDEREYQKILIDTSKELQKELCHRSKILIKYDSTMQFVNKVCNIF
                     DETKNKKGIRSVGRMKEQFYGSKGTEMNKIFQVFYPDEFKVKPFLSYPIGQFIYAIHN
                     MWDLKNHKLILNSRDLAECLNLDVWHDIHPLEVFESLRFYIGIDKEPNGMNVKDFIDR
                     IKKLIYFKERNENKMKNLDNLSYLNLTIDQYNRFIQVIENINEIANKIFCNKSQTSKK
                     HFMDLLEILNDEKAWKPLLEEEKRLMDEIKNQIIHIDDETNKTDLNTIKDTMAYYLDS
                     KEGTDINWLVRDFEQLEGDILSEAANYKNNTLRQKCYHLTMLSNENMINCDIDNLPWP
                     LSDDFIISKNISSFIHTICINYAKYKRCLLFQGLYYLINNPIISLKLSYIENQGEYKH
                     TPYYILNMFMNIGKDFDQSNCRNIESCTSPINKEPKKRFKIDKKWHKDAIESFSCCPY
                     KFMYGYVINDAAKHYKDELQVKMYLGEIIKYYISIAWKKILQYHKKLLLDQKFNLLKK
                     WTAGERLDCLEKSLPETLEPIYGNYFIKSEINKIIVDNLEYLKNKRIDNKRVYFTEEC
                     KIYEVDRELYHCWIGKISNHNLYVTNKNKIINIRNRLNLLNANEYINDYILGINDGWY
                     FKKDNIVVEGGYKVSEHACRYCSYNKICCYQYRIKPIHLLHSKEDLID"
     gene            complement(15023..15406)
                     /locus_tag="KRH82_002267"
     CDS             complement(15023..15406)
                     /locus_tag="KRH82_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DndE family protein"
                     /protein_id="HBG8655543.1"
                     /translation="MRFKLKTSTQTKEIFEELGSRMNLKPFALCKLAISMSLSYSESI
                     ESYENIDNNGLELNRQTITNQYDTLFKTLFEQHIGRHLSDNEYFPNQVKLHIDRGAIM
                     LKNRYNYSSNLEHFITQIIQEDNNL"
     gene            complement(15409..17568)
                     /locus_tag="KRH82_002268"
     CDS             complement(15409..17568)
                     /locus_tag="KRH82_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8655544.1"
                     /translation="MKINKLVLKNFRSYEEETTFNLNTTSDKNIILIGGKNGAGKSTI
                     FEAIKLCIYGPMAYKYQGFNASYISQVKSNINNNSLINSKIDTLVSVDIEISEGTEEN
                     IYTLIRQWTFKDEKLNETFLVYKNFSTTPLNADELNYFENYITSIISPKIFDFFFFDG
                     EHLYDFFVGKNSNIHLKESLLSLCNFDTFDILKKVLISTNRSNKNVSDEINIVKDSYL
                     NLEMEINTLNSQEEIFSYELQKISNEIEKLQQEQLEVKKEFRKKGGILAEERETLNSR
                     IAELEGKRFIINQNIKEFCNDILPFLIVKKQISNLEKQLKTENDILLYSRLKDKLNIE
                     YIKNLLSDKIMPSALDEIALTVSEALTEDIKPDSYEENFKSIHNLSDDESRKLLSLIN
                     TILNFDNNSIINSFEEHRSISNELADIRHKLNTSLKDESLNTYINDMSNLSSKIDSLL
                     GSKNLLVTSLDKLKLEIAETKSRRDKSKAKYIYLLQHNNIVDISTNLILMLDEIVTTL
                     TETKIKLIQDNFMYIFKKIIQKDNFISHIDINVNFDISLYINKIYNSLELENLAKNIG
                     IEGMEKKLGKLFFDDLFNLYSVEDKYELFNVIRNNTQSTFLNLRTKVDIDEFSSGEKQ
                     IYVLCLYWALLKSSGIEIPFIIDTPYARIDDTHRNSITSEYFSTISHQIIILSTNTEI
                     DEKLYKIIKPKLSREYLLEYDSKNKKTIQNKGYFFEV"
     gene            complement(17555..19021)
                     /gene="dndC"
                     /locus_tag="KRH82_002269"
     CDS             complement(17555..19021)
                     /gene="dndC"
                     /locus_tag="KRH82_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA phosphorothioation system sulfurtransferase
                     DndC"
                     /protein_id="HBG8655545.1"
                     /translation="MAVNYLDNNNLENLYDEMQAVYLNDDRPWIIGYSSGKDSSCVVE
                     LTFRMLKRLPKEKRHKEIYVISSDTLIENPIILDYLKNNIDKINESATEHDLPISAQI
                     VYPELNDSFWANIIGRGYPTPKSIKYRWCTERLKIKPSNKFIKEKLEQKDVIVLLGVR
                     KEESSARKSRIEKREIEGYLLTPHETLRGKNKLAYVYTPIVNFSTADVWDVLYHQNDN
                     FIDFGGEFGPSPSTSWGTDAMELFQMYMKGSGDSDECPFIADEASAKSSCGNSRFGCW
                     ICTVVKEDKSLNGFIESGHDELKPLLEFRSWLISERDKPKNRKKHKRNGSVIKKDGKI
                     MFGPFTFEARQTILRKLLETQLEMQKFYPDLQLIQLGELKAIDEIWDNEEDLTGNILS
                     KIYKEVVGKNLPWSEYKKPVFDDLTLNIISEKCSEYDINIDLFNKLIIDTNKYKYFSN
                     NTKLKTSIERILNQQWLHQDIIEKIEEEGNKELKYENK"
     gene            19630..19782
                     /locus_tag="KRH82_002270"
     CDS             19630..19782
                     /locus_tag="KRH82_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655546.1"
                     /translation="MKNLNKNKILGEVIITITACDDEKEIQIVIKNQVDNILKNKNKE
                     YRIKKI"
     gene            20099..20344
                     /locus_tag="KRH82_002271"
     CDS             20099..20344
                     /locus_tag="KRH82_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBG8655547.1"
                     /translation="MLIHTKNKTFDAICILEKIEKDLNIEELVRCHKSYIINLNYAEN
                     IKSNTAILDSQEEVPISRYRYKDIKEGFLKFIGDRIC"
     gene            20338..21731
                     /locus_tag="KRH82_002272"
                     /pseudo
     CDS             20338..21731
                     /locus_tag="KRH82_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            21991..22248
                     /locus_tag="KRH82_002273"
     CDS             21991..22248
                     /locus_tag="KRH82_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655548.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLGNLEYTKEQPSQVLH
                     YSITKDKKDTKEILSIQCVKDFSYNEKLSEDDKFIMAIYNI"
     gene            22253..22432
                     /locus_tag="KRH82_002274"
     CDS             22253..22432
                     /locus_tag="KRH82_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655549.1"
                     /translation="MIHIEISEKEFFRKIEEVFDKGEENVEVDNLGDIKIQVKKFDDK
                     TKPLELKLIKEFKLK"
     gene            22444..22638
                     /locus_tag="KRH82_002275"
     CDS             22444..22638
                     /locus_tag="KRH82_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBG8655550.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSSDDIERITKEKYTKEN"
     gene            22872..25424
                     /locus_tag="KRH82_002276"
     CDS             22872..25424
                     /locus_tag="KRH82_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8655551.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPNDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKSDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLFRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEVLYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDYIDEKLNDFVEEGSLDD
                     IKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMKV
                     RVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNNE
                     IQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNLL
                     IRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAYI
                     NYGIENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
     gene            25441..26103
                     /locus_tag="KRH82_002277"
     CDS             25441..26103
                     /locus_tag="KRH82_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655552.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(27116..27687)
                     /locus_tag="KRH82_002278"
                     /pseudo
     CDS             complement(27116..27687)
                     /locus_tag="KRH82_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            27956..>30893
                     /gene="cbpA"
                     /locus_tag="KRH82_002279"
     CDS             27956..>30893
                     /gene="cbpA"
                     /locus_tag="KRH82_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBG8655553.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGGDANAGNAEGDANAGNAGGDANAGNAGGDTNAGNAEGDANAGNAGGD
                     ANAGNAEGDANAGNAEEDSNAGNAEEDSNAGNAEGDMNALVVEEATAEDPTSVGDFKI
                     SGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIVIPKDVKAELIFDGVNIKT
                     ASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGMRAGKGTTLIIDDSVVNRD
                     IEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRGSLKVVGNYYSAGIGGGNT
                     ESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGDITINGGTITAKGAYHGAG
                     IGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSYGGAHGSAFGDGCVNPGTN
                     RGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSLKATTFKSLGGAVAYGDLE
                     KKTKVFMNKISLTYLGQDKVSTTLVDDFKMLIDGKIYPYGAPSYTDAQGILYLWFSDK
                     FTGSEVSVNLVVIDKITGEVLKPDDFYIKDIGSGSQFLKQYEEFTIDDTPPYLIIKRY
                     DGLPFEEDVEKSFLDWLLKDGGIPITTPKGEKLTDKKFMTISSQRLNEETMEPDINLG
                     SDDLTKQVDAGKYQLSITSTQFSSIYPFKDAYWGHRAYYKAEIIPADTETSLVVEESK
                     AKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYINGKEYKDPVELKTHNKGSE
                     SHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIEGSEDEKKLKLDMTNVDVD
                     GDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGEWKPSTEGGNGDGIWKPDK
                     NIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGSGGYDTGNPNLNKPDPDNG
                     GNSKPDP"
BASE COUNT        11840 a         3466 c         4599 g        10988 t
ORIGIN      
        1 tataatatgt aatatttttg ttttgaaatt tataaattag tattactggt tagagttagt
       61 ttagtattaa gtatattcga agtagttttt tagctatttt catacattta tattacttaa
      121 ttatatatag cctaactaac ttaatatatc agtgaaatat tgactaaaat gcctaaatat
      181 gttatcatac aagttagtca aataatttgg caacattaaa tatttagtaa atttctaata
      241 tttatggaag aaatttctag caaagaaggt gagatttata tggctggtaa aaaaatatta
      301 gcaacaaaca aaagagcaag acatgaatat tttatagaag aaacttatga atgtggaatt
      361 gaattaaaag gaacagaagt aaaatcaata agacaaggca aagttaacct aagtgatgga
      421 tttgcatctg tagataatag cgaagtattt ttaaaacaag ttcatataag tccatatgag
      481 caaggaaata tattcaatgt tgattcttta agagttagaa aattattact tcataagcat
      541 gaaataagaa agcttattgg agcaactact ataaaggggt attcacttat accacttagt
      601 ttgtatctaa aaaacggtaa agttaaagta gagattgcct tagcaaaagg taaaaaacta
      661 tatgataaac gtcaagatat ggctaagaaa gatgcacaaa gacgtataga aagagaaatg
      721 acaggtaagt attaaactag ataaaactgt attttttaga ataaaattct ttattatcta
      781 gaacataaca ttgattttta ttcttaaaag tattatatta tatatacatt aaaaatttaa
      841 taaaaatggt gataaagttt gcgaaaagtc tactggacta taaactactc aagggggcgt
      901 aaaggtttcg acgtgggttt ggaacttgag gctgcatgtc gtgttactct gggtcacgta
      961 aaaactgggg aactttaaaa taaacgcaga cgataatttc gcgatagcag cctagttgct
     1021 gctcgtccct cttagtcctc ctgccgacta agactggacg tcattatgca gggaactact
     1081 ttaggggtgt ctcgacttga agtagattaa ttgggactgg ctaagcatag agcctgccac
     1141 ttggcgctat gtgaggtgag atattagtga agttggctaa gcatgtagat gcagcaagga
     1201 aaagatttgc ggacaggggt tcgactcccc tcgtctccac caattttgaa aaaagaatga
     1261 tgaaatactt ggaaatacta gtctttattg actagtattt tttattttgg agataaaatc
     1321 caccaaccgt accccaacca cagaaaatga ggtatttttg agagtatatg ggggtgcatt
     1381 tgagtgtatg aaaacattta cttatcatta cattagagag gataggaatt taatacatac
     1441 tttagggagc tttatcagaa gccttaaata tgaactcaga agaagtttat aaaatactta
     1501 aacataacac tgatatttca aataccttgt tatgaatcat tacattttta aagtaaaagt
     1561 tacatagtag aagatttaat agaaccactt aaataaaagg aagtgttatg atgattgcat
     1621 atcatagttc ttattgtata gcaaaaactt ctgattctat attctaaaga ggttctttaa
     1681 attttggtaa aagattttat gtgattagta taaaaacgca gatgattaac aggatggaat
     1741 gatttaagag aagaggtaaa aaggtgtatg tagatagttg ttttttagaa ttgatataaa
     1801 atcaatttaa ttatttaata tttatttttg taaaattaaa agaactgtag atacgtttaa
     1861 ataaaccact atttcacacg cgttttctaa aaatagtggt taaaatgtta ttttttatat
     1921 ttatttacaa ctttagtaat ttgattatga tgaaaaggtt tgttaggatt caatttttta
     1981 gttaatctat tagctatttc tctaagacta atgttacaat ctaacataga taatatttca
     2041 gtaatatttt cttctagtaa ttttatagaa ctttttggag gtattaaatt ttgttttgat
     2101 atatgttctt tatatacttg cccaatcaca tttaaatcaa agggttttcc tattaaatta
     2161 gaacctaatt tatgtgatat ttgtcttaat gaataattat aattatgttt aaggtcaata
     2221 agagtatcta tatgtttatt tagtaattct ctttgtgtag gaggtttttc tttaagttct
     2281 tctcgacgag tatatttgta atttttataa atacttatta ctgttttatg gtcataaggt
     2341 ttatctcttt tcaccaaaat agcaatttcc ctaccaattt tactaaatga gtaattttcc
     2401 acatctctta attgtacaat cttttttatg atttcttgat tatacaaata ataatctcgg
     2461 ttagttcttc tacgctgaac tttatcattc atattatctt tttggtcgcc agttcttaag
     2521 tgacttgctc taatacataa tggattatca caattgtgta gaatatattt gccactactt
     2581 gaagtattag tataagtgtc ataagagtac ctacttgctt ttatttgttt gttattttta
     2641 tggactacag gacagtattt ttcacttccc caatttgctt caatacagac ttctttaggg
     2701 aaaaaaattt caagtttatg taatgcctct actttttctg cattagttaa ataaatataa
     2761 ttccatacac tacctttttt aatatagagt aatagctcta atggtataga taaaaattta
     2821 gctatttctt ctattgaata attaaattca gagttattca tattatttaa taaatatttt
     2881 gttaaatata ctgattcttt agttaaaact atctcattaa tttctggtct atcattgaaa
     2941 tatttatcaa gaatattttc agatacttta cgttcttcta tatgacttgg attaacacaa
     3001 catcgattgt aacaagtatg atgtgcttgg tatccatttc taattggcct ttgtagtctc
     3061 tcttctagta ctattcttgc agctcttaaa gtaccttctt tatttgaatt aatttgacca
     3121 taaccatcac ggtctctata tcctggataa ggaatgcatt caatcaattt tatcacctca
     3181 tttattaata ttaaattaat ttgtatcatt attttgattt tgtaattaac tatatgaaat
     3241 catagtattt ttatgtgttt gatttttaca atgaaaatat tttatctaac ttttctacag
     3301 cttcaacttt cttatcttcc ataacttgag tatatatatt taaagttatt gatatatcat
     3361 aatgacccat taaaacttgt acagctttag gagggacatt attctcaaaa agtctagtcg
     3421 cataagtttt cctaagacca tgaaacttta taggctctat atctagactg tttaatatag
     3481 attttagatt ccttaaaggt cttttatcat ctatagggac acctaattta ttgcaaaata
     3541 cataattatc atttctatat aattctccag cctttaatat atctgtattt tgacttactt
     3601 tatgttcttt caatttattt aagatattct ttggaatagg tacagttctg taagaatttg
     3661 atgtctttgg ctcttgctct aatactttaa gctctctatc tccattttta tctataaaat
     3721 atgttctttg aagcgttctt ttaactgtta aattagaatt cttaaaatta atgtcaaacc
     3781 atttaagtcc taataattct cctaatctaa gtccagtacc aagagcaagt aaaaataata
     3841 cctctaattt atgtccatct atagctttta taaaactctt ttgttgttca agagtcaata
     3901 tttcaatctt attttccttt ttctcaactg gtatatttac catagtacaa taattacgtt
     3961 gtataagacc ttgtttttca gcttctgata agcaggtttt cagtttagtg tttatttgcc
     4021 ttatagtagg tatactttta ttggaatcaa gcaatctatt gtaatatttt tgtatgtgag
     4081 atactcttaa gtcatttaat ttaacattga ctaaatcagt atctttaata taattgcgat
     4141 agatgctttc atatctctca aatgacttag gttttaaatc ttttattcta tatttaaata
     4201 accaattgta aaaccaatgc tctaaagtta ttttatcatc tgaaatatca gagcttaaat
     4261 aatattgttt tttataagca tctaatttat ctttaacttc tttttgagtc ttaccataaa
     4321 attcttttct tattggtttc ccatcttcat tgtaaccaat cattatacgg gaacgccaac
     4381 catctttata ttttccgata gagccttctc cattagctat tttagttgcc atttttaaac
     4441 agctccttat atgatttata gttatattca tcaaagaatg taatacattt ctctaataag
     4501 aattttataa cttcatcacc ttctagtgtt tcatagaagt ttagcattaa tgtgttgtat
     4561 tcttgtttat gtttagctgg tattgataga actcctatat cattacttat aagtattagg
     4621 tttgaggtaa gtctagcagt tcttttgttg ccatcataga agaattgaca ataggacaac
     4681 cataaattta ttattatagc cttttctaag gggttagtta ttttatttat gatatttatg
     4741 tcatttacaa ataaatcatt taatagagtg ggttctatgc actcatattg ggtagtacca
     4801 gctataccta tattaccatt tctgaaatct ccaacgatta gagcttcatc ttttgcaact
     4861 attttatgta tagagcaaat tgtatcttta tttaaagata atttttcttt gttacttaat
     4921 tttattacat aatcccatga tgattttata tttagtattt gattttggtc acttaattta
     4981 tgtccaccta ctgttatacc atcaagtaat gtttgtactt ctgggaatgt gaaggggtta
     5041 ttttctaggt tacccatatc atatacaaat tcacttatca ttcttctaat gtatgttaaa
     5101 gtatattttt tatctccatg aggtagatta gtagggaatt tatgtgtgta ttttggtata
     5161 tatgatttat tcatgatttt agctcctttc atatctaatt tttatttatt aactatgaat
     5221 gtataaaagt taataggtaa acctatattt tgaaaatatg caatactaat attcttcatc
     5281 ctcatcttca ataagaccat tagagttttc ttgtataaaa ttttcaacaa gaccatttat
     5341 cacccaattt agatttttgg agaagtcttt gaagtcagag aagtttaggt taattggttt
     5401 tattgtatct gcattatctg taatttcaaa ctttttttat agtctgtttt tatatcataa
     5461 ccataatttt ctaatatgtg aattactaaa tccaactctt tatcaaatac ttttaaatta
     5521 atattattat ttgttaaagt atctaaatca ttttcttcaa caatgagttt atttatagca
     5581 attgataaag cagtagctat ttttcttatc atatctaaac taggtattct ttgattttgc
     5641 tcatatttag ctatagcatg aactgaacaa ccaatcttgt tggttagttc attccttgac
     5701 atatttatcg atttcctata ttgtttaatc ttttctccaa ttgtattatt tattataatt
     5761 ccaccttaaa tatatcatca aacaatgatt atatttttac acatataaag gagttatttt
     5821 ctagattatc tatgttatat actaacttac tcataattct tttaatgtat atcagagtat
     5881 attttttatc tccatgaaat aaattagtag ggcatttata tgtgtatttt agcatatatg
     5941 atttattcat aattgtaact ccattcatag ttttttatca ttgctttaga tagtattgat
     6001 attattttat attttagtta gtagtttttt tatttcttta agtgtatttt caagcttttc
     6061 atttttttcc tttaattcgt tattttcttg taataattta aagtaatcat tatttttaat
     6121 agtaatattt tctttttgag atattaattt ttttagtcga atattacttc cattatctgt
     6181 tgagtcacta aagtaatcat agattgtttc tatattttct tctgatagac caatatctaa
     6241 taattcatca attgattgtt ttgtaagaac atcattttta ataatttctt ttatgtcatc
     6301 aggatgtaat gaaaaatcta attcagtatt agatatacaa tctgaaagta tccaattata
     6361 aacttgattt tcatttagtt ctaatttttc accaagttta taatattggt ctttatcaga
     6421 ccaagcacct agcaataaac ttgaggtaat tctaatatca tcatcttcca taagatttga
     6481 aatagcattt aaaaattcat caaaagaata gtattcttct gggaataaag actgtaaaaa
     6541 gtataaaaca tcttcattag taattacttc attttcaata tcaaaataaa agatagtctt
     6601 ttcaattttc aaagctttag cgagttttga taaggtatct atattaggta ttcttttatc
     6661 attttcataa tttattagag catttcttga gatgtcacta atttcagcaa gttgaatctg
     6721 tgttagttct ttttgttttc ttatcttttt taagtttttt ccaatttgca atattatcac
     6781 ctcgtataaa gtatatccta aaagtacaca aatgagaaca gaagaataat atatttttat
     6841 tgggtatata catatatgga cattataatt aaaatataaa gtttacaaat gtaaactaga
     6901 aaaggtgata atactcttat atatcagtta gaaaatgata taaataaaac taatcagaaa
     6961 ttaataaaaa aggattcaag tataacggct atatcagaga gagcatttga ataatataaa
     7021 tgatgaaata aatgaaggtg ctaagactag aataaagttc ctagagaata ttataggagg
     7081 tttatatggt ggtgaactaa ctccaatagc agttaaaagt agaagaggaa aaatagcatt
     7141 agctttacaa atacttagaa atgtaatact tcaaggtaag aaagtatttt ttataagtag
     7201 agaaatgagt aatatacaga ttttgtttag aaatatagca tcactaactg gaatatcaat
     7261 tgtaaaaatg aagaataaaa acttagatga tgatgaaata gtcaaatata tacaagtttt
     7321 aagtataata aatcaagaaa ataatcttta tataaatgac tctgtaaata caatatcagg
     7381 gataaagcga gaaataaaga gtattaaatc tagtttagta ataattgatt atttgcaaat
     7441 tttggattat gaagctaaag aaataggaga aactaaattt gctgacttat cagagcaagt
     7501 aaaaaatatt actttaaaat ttaatatatc agttgttcaa tttgctcaat taagtacata
     7561 tgcatagaga tattttagaa aaagataagt tatgtaggat attgcaaagt gattagagag
     7621 attaataaat tgttagaaaa ggttttacta gatgggaata aaaaatgtgt attagtagag
     7681 tgggtattag atagtatcat tttagaagtt atatatagca tgtttatatt aaagtagtaa
     7741 atatattaat ctatgtactt gttttttaag taaaataata gcataaaata aaggttttta
     7801 aaagtatatg tctaatttta taaataaaca tattatataa ggacctgaat aaatatttga
     7861 agagataaaa ttatattaaa cttaatatca aaatgcttaa agatgtctta ttttaatatt
     7921 ccttatcata gttagaactt atagaattct atatatcata atagtggtaa atttaaatat
     7981 gtatagaaga ttaaataata atatatgttt attataaaaa ataatacaaa ttaatgtgta
     8041 taaaaagatt tactaaataa gtataatcaa gtaaaaatta aatatgaaga tattaattat
     8101 actagaaaga taatagtata agcaattaag gatgcaatat taaattctta ataaacttat
     8161 atctagggag gatatcaaat gggaaagatt gaacctaatc aagaggaccg tatatatgaa
     8221 gatttatacc agggaaatag cgctgaaggt aaggtatgtg aatggataga agaagctatt
     8281 aatgatgatt gctatgtagg acaacataga tttaagattg agacaagaga atgtgatatt
     8341 gctatggtta taccaaatag aggcatatta ataatagaag taaagggcta tactgtagaa
     8401 atgattgatc atatgtcaag taattttatt atacatgtaa agaaagagta tgaaaatgaa
     8461 agatttaaaa ctggtgaaag gcatccagca gaacaagcaa atgattatgt atttacaatg
     8521 atgagagatt tttcaggttt tttaaaaagg aataacatat gtttaccaat atgtaaaata
     8581 ggacgaatgg cagcaatgcc taatatgaca gataaagagt atgaggaatt atacttggat
     8641 tattgttatt caacaaaact tgtaatcaca aaagattggt ttaagaataa aaatatattt
     8701 taccatcgtt ttataaatgc acttaatata atttttaatt ctataagcag tgaagtagat
     8761 ttcgatgata gttattataa tattgcgaga aggtatattc ttttaggtga acgtaaaaaa
     8821 tatgtagatc tatgtaaaga gcaacttaag cgagaagaag aattgggtat tgattttata
     8881 atagacaata ctaatgaaga agtagatcaa ctttgcaaat cgaatgaagt taatgatgaa
     8941 gaaatggaat tgataaaatt ttcttctgtt ttacaagaag aattaacgga atcacataaa
     9001 ctatctaaaa ttattcctta ttctaaatta cgtatagtta agacaggttg tgaaatagaa
     9061 ccacttttgg agatttgttg taatgaacgt aaagaaggaa taaagcagtt tctaatatta
     9121 gttaatttta caagagatga gaaagaaaaa atattgttag aatatgaaaa aagattttta
     9181 aataagtata aggaaaatga actgttattt ttattcaata tgtattttat agatttatct
     9241 aatgatgata caagcattga caatctattt agtaatcatg ataatattga aattattaat
     9301 ggagagagaa tagaagagat tgtcaaaata aaacctgaca attttattgt acaagaattt
     9361 acaccaaaag atctgttaga tcaagctttg tggaatatat tatgtattgc agataatttt
     9421 acttcattta attttgatca gtatatagtt gaacattcac ctcttcgtca aaacattgtt
     9481 gtaactgcaa gtgctggtac aggaaagaca tatactatgg ttgatcgagt ttcatttgtt
     9541 gcacatatgg agattattta tagaaactct aaggaatcta ttagtgatct aatctctatg
     9601 ataacattta ctaataattc aacagatgag atgaaggaac gattaatgaa acattttatg
     9661 cagtactttg agttaacaca taataaagta tatatggatt tattagaaca attaggtaga
     9721 atgaaaatta aaacaataga ttcatttaca aaatatattt tatctaaatt tgctcattta
     9781 ttaggtcttt ctaatagttt ctcattaaaa agcggaaagt ttgaattaga gaatatttta
     9841 agaaaatata ttaatgatga gataactaag gaaattatag atgatttcca taatataaat
     9901 atttatgaaa ttgctaatca tattcttgct ttgcgttcgt ttcttattaa tcgaaagatt
     9961 caatttgata aaataaaaca tgcttctatt gtgggacctg atgtagggaa gggaactatt
    10021 cgtatgaaaa attttataga gtctgtactt atttctacaa atagtgaata tgatagtttt
    10081 aattgtagtc aaaactttat ttcgatgaat gaattagtta ttcaattaga gaaggtcaaa
    10141 aataaattga taaaaactag ttgtgttaat aatactaaag aaaattatga aaaatacttg
    10201 tttatagatg aatttcaaga tacagataat aaacagatac aattaataag attttttgcg
    10261 gactatttca atattgcact ttttgttgtt ggagatgaaa aacagtgtat ttatggattc
    10321 agaggagcag aaagaacttc atttttagaa cttacatgtg tagatactaa ctttcaacaa
    10381 agaaattgga tatcatgttt tctaagaaaa aattatagaa cagaggaacc cttagtaaaa
    10441 aaaataaatg aagtgttttc taaaatgcca aatgattttt tcccttatca aaataaagat
    10501 aaattagtag ctcaaaaagg aattggaaga atttattcag ggtgttatga acaatttaaa
    10561 tatagtgaaa ataacttaat agaactcgta gataattgtg ttaaaagaat gaaaaaaaat
    10621 aatgaagatg gacaaattgc tattttaaca agaaataatt atgaggttga tcaaatacgt
    10681 gctttgtttg gagagaataa agaatatgaa attaaatttg ataatggtgg attattttat
    10741 aatactgatg ctgttattga tttttataaa ttagttgagt ttttgatgga tacagaagat
    10801 ggtgctaaac gatatagtat tttagaaact ccttatagtg atttcagaat taaagaatcg
    10861 aaaataaagc tatatcaagc ttatgaaaaa atggatgttg aaacctttga aataattagg
    10921 tctggaaata atcatgtatc tttacgaaaa tattatgatg tattatataa ttatgggaaa
    10981 aaacatccaa atttaaagaa tagcccaagt ttaaagatcc ttcgaatgat tgttaatgaa
    11041 attaaaccat gggaacacta tgtaccagaa agatataaaa ctgttgattt taatgatata
    11101 tgtaaccaga ataagctcat tgaagctaga aatgagtatc gtcaaaattt atttcagtta
    11161 tttcaaaaat taatagatga taataaaaca gactatttaa cacttaataa gatacatcaa
    11221 attttaacta ttggtatttt tgcaatgcaa gatattgata ttgatttgcc taaaaataat
    11281 ttttttggag aaaaaataag tgtattatgt acaacagtac ataaatctaa aggtcttcag
    11341 tatcatacag taatcatgcc atttacaatg aatgatataa cagagtcaag aggatcaaca
    11401 caatttattt atagagaaga tacaaatgag atctatatgc aattaaaaga agctgatgga
    11461 aagtgtctaa tttatgaatc aaccaatttt gattgtgaaa ataataagaa aaatgaaact
    11521 atacaatcag aagaattaag aattttatat gttgcattaa cacgttcaaa aaaatttttt
    11581 tactttatgg tggatgaaga aagatttgaa aaaaataata cttctaaaaa aaattgttgg
    11641 gcacattatc taatgtaagg tggaggaaaa taatatgaaa atctatacat ataaaaattc
    11701 tgtacaattg aaagatgcaa tcttctggaa tgaaatagaa ggagcacctc atttttgttc
    11761 ctctgaagta ctagcaatag gaatgagaaa attttatggt agaaatactt ttccatgcat
    11821 ttctactata gatttattga taaaagaact ttatccaaat tggcttaaat ctcatagtga
    11881 tatagagcga tataaagata tatctaaatt aattaatgaa cttaatgatt caagtacaga
    11941 gggtttaaga caagcttttg taaaaaataa aaaatctata ctagattctt gtaaatattt
    12001 gattgaaact gaagatttgc tcttaaaaga ttattacaat aagaacatat ttaataaatt
    12061 ttcagcaatt aatgatattc aagaagtttt taaagaaaag atactgaaaa gacttttaga
    12121 acaaatatac attgatggaa acaaaaatta ttggaaacct gagtggatag atacattatg
    12181 ggttaaatca aagttaagtg aagtaattca taaatgtgtg ataaaagaaa ttagtgatat
    12241 tgttaagaat acagaagaaa agagtttaaa tcataattat gatgaaggtc atatttttga
    12301 aatatttgat gaactgtttg accagcatgg attatttaat atatcagata agactttaga
    12361 atattggaaa tttaattcta aagatgattt gcttgataaa attggatact catcaaaaga
    12421 actagagtat gttcgtaatc tagctactac tgaatgtaag tcatataaga ctatagtaat
    12481 tcatggtgtc tatcatttaa atccaattca cttaagattg ttaagagatt tagaaagaga
    12541 tcataatgta attgtattaa attgttataa taaagaattc aatcatattt atgaattttg
    12601 gaatgatata tatgatcatc taattaaaat atttcaaatt ccaaagaata atataaaaat
    12661 tgatagtcat gattctgcta atcacagaga agttggtagt atatttgctg aagttgtaaa
    12721 tggtgtaatc aataaacaaa gtaatttctt taagataagc agaaatgaat ttggcccaga
    12781 cttaaattta aattctaagg atattgatga actttttaat cataatagta gtcaggatat
    12841 tagatatata ttaaataaaa gtgaagctat tattcaaaac tatgaggatg aagatgaaag
    12901 agagtatcag aagatactta tagatacatc aaaagaactt caaaaagaac tatgtcatag
    12961 aagtaagatt ttaataaaat atgattctac aatgcaattt gtcaataaag tgtgtaatat
    13021 atttgatgaa acaaagaata aaaaagggat acgttcagtc ggaaggatga aggagcaatt
    13081 ttatggttct aaaggtacag aaatgaataa aatatttcaa gtattttatc cagatgaatt
    13141 taaagttaag ccttttctta gttatccaat tggacaattt atttatgcaa ttcataatat
    13201 gtgggatttg aagaatcata aacttatatt aaatagtaga gatttagctg aatgtttaaa
    13261 tttagatgta tggcatgata ttcatccatt agaggtattt gaaagtttac gtttttatat
    13321 tggtattgat aaagagccta atggtatgaa tgtaaaagat tttattgatc gaataaaaaa
    13381 actaatatat tttaaagaaa gaaacgaaaa taaaatgaag aatttagata atcttagtta
    13441 tcttaattta actatagacc aatataatag atttattcaa gtaattgaaa acattaacga
    13501 aattgcaaat aagatatttt gtaataaatc acaaacaagt aaaaagcatt ttatggattt
    13561 actagaaata ttaaatgatg aaaaagcttg gaaacctcta ttagaagaag aaaaaagatt
    13621 aatggatgaa attaaaaatc aaattattca tattgatgat gaaactaata agactgactt
    13681 aaacacaata aaggatacta tggcatatta tttagatagc aaagaaggta ctgatattaa
    13741 ttggttggtg cgtgattttg agcaattaga aggcgatatt ctttcagaag cagcaaatta
    13801 taaaaataat actttgagac aaaaatgcta ccatttaact atgttgtcaa atgaaaatat
    13861 gattaattgt gatatagata atttaccatg gccattaagt gatgatttta ttatatcaaa
    13921 aaatatttct tcctttatac atacaatttg tataaactat gcaaaatata aacgttgtct
    13981 attgtttcaa ggattatatt atttgataaa taatccaatt atttcactta agttaagtta
    14041 tattgaaaat caaggagagt ataaacatac accatactat attttaaaca tgtttatgaa
    14101 tataggaaag gattttgatc aatcaaattg cagaaatatt gaaagttgca cttctccaat
    14161 taataaagag ccaaaaaaac gttttaaaat agataaaaaa tggcataaag atgctataga
    14221 gtcatttagt tgttgcccat ataagtttat gtatggatat gttattaatg atgctgcaaa
    14281 acattataaa gatgagttac aagtgaagat gtatttagga gaaattataa aatattatat
    14341 tagtattgcg tggaaaaaaa ttttacaata ccataaaaaa ctattattgg atcaaaagtt
    14401 taatttactc aaaaaatgga ctgctggtga aagactagat tgtcttgaaa aatctttacc
    14461 agagacacta gaacctattt atggtaatta tttcatcaaa tctgagatta ataaaattat
    14521 agtagataac ttagaatatt taaaaaataa aagaattgat aataaaagag tatattttac
    14581 agaggagtgt aaaatatatg aagttgatag agaactatat cattgttgga taggtaaaat
    14641 atcaaatcat aatttatatg taacaaataa aaataaaata attaatatta gaaatcgtct
    14701 aaacttacta aatgcaaatg aatatataaa tgactatatt cttggaatta atgatggatg
    14761 gtattttaaa aaagataata ttgtagttga gggaggatat aaagtatctg aacatgcttg
    14821 tagatattgc tcatataata aaatatgttg ttatcagtat aggataaaac ctatacactt
    14881 gctacattca aaagaagatt taattgatta ataattagat aaactttaag aactatatca
    14941 ataggataga cggttttatt tattttctat cctattgatt aaatctaaaa gttttagttt
    15001 tttagttaca tattgaatca tattatagat tgttatcttc ttgtattatt tgagtgataa
    15061 aatgttctaa attactggaa taattgtatc tgtttttaag cataattgca cccctatcta
    15121 tatgaagctt tacttggtta ggaaaatatt cattatcact taaatgtcta cctatatgct
    15181 gttcaaataa agttttaaat aaagtatcat attgattggt tatggtttgt ctattaagct
    15241 caagaccatt attatcaatg ttctcataac tttcaattga ttcactataa cttaacgaca
    15301 ttgaaatagc cagtttgcaa agagcaaatg gtttcaaatt cattctagat cctaactctt
    15361 caaatatttc ttttgtttgt gttgatgttt taagtttaaa tctcataatt acacctcaaa
    15421 aaagtatcct ttattttgta tagttttttt gtttttgcta tcatattcaa gcaagtattc
    15481 tctacttaac ttaggtttta ttattttata taatttctca tctatttcag tattagtaga
    15541 tagtattata atttgatgac ttattgtaga aaaatattca ctagtaatgc tatttctatg
    15601 agtatcatct attctagcat aaggagtgtc tataataaag gggatttcta tacctgagga
    15661 tttaagtaaa gcccaatata aacaaagaac atatatttgt ttctcgccac tagagaattc
    15721 atctatgtca actttagttc ttagatttaa aaatgtagat tgagtattat ttcttataac
    15781 attaaatagc tcatatttat cttctacgct atacaaatta aataaatcat caaaaaataa
    15841 ttttcccaac tttttctcca ttccttcaat tcctatgttt tttgctaaat tttcaagctc
    15901 taaagagtta tatattttat ttatatataa agaaatatca aagttgacat taatatctat
    15961 gtggctaata aaattgtctt tttgaattat ctttttaaat atatacataa agttatcctg
    16021 aattagttta attttagttt ctgttaatgt tgttactatt tcgtccaaca taagtataag
    16081 attagtagat atatcaacaa tattattatg ttgaagtaaa tatatgtatt tagccttaga
    16141 tttatccctc ctacttttag tttcagctat ttcaagtttt aatttatcta aagaagtaac
    16201 tagtaaattc tttgatccta ataaagaatc aattttgctt gataaattgg acatatcatt
    16261 aatatatgta tttaaagatt catctttaag gctagtattt aacttgtgtc ttatatcagc
    16321 taattcattt gatatacttc tatgttcttc aaaagaatta attatagaat tattatcaaa
    16381 atttaaaata gtgtttatca gagataataa ttttctactc tcatcatcag aaaggttatg
    16441 gatagattta aagttttctt cataactatc tggctttata tcttctgtta aagcttcaga
    16501 aacagttaaa gctatttcat ctaaggcaga aggcatgatc ttatctgaaa gtagattttt
    16561 tatatactca atatttaatt tatccttaag gcgagaatat agtaggatat cattctctgt
    16621 tttaagttgt ttttctaaat ttgatatctg tttttttaca attaaaaagg gaagtatatc
    16681 attacaaaac tcttttatat tttgattaat tataaatctc tttccttcta attcagcaat
    16741 tctagaatta agggtttctc tttcttctgc taggattcca ccctttttcc tgaattcttt
    16801 ttttacttct aattgttctt gttgtaactt ctcaatttca tttgaaattt tttgtaattc
    16861 ataagaaaaa atttcttctt gagagtttaa agtattgatt tccatctcta aatttaaata
    16921 gctatctttt acaatattaa tttcatctga aacattctta ttagatctat tagttgaaat
    16981 caacactttt tttaaaatat caaatgtatc aaaattacaa agagataata aagattcttt
    17041 taaatgtata tttgaatttt tacctacaaa aaaatcatac aaatgttctc catcaaaaaa
    17101 gaaaaaatca aagattttag gagaaataat agatgtaata taattctcaa aatagttaag
    17161 ttcgtcagca tttaatggtg tagttgaaaa atttttataa actaaaaatg tctcatttaa
    17221 tttttcatcc ttgaaagtcc attgtctaat taaagtatag atattttctt cagtgccttc
    17281 actgatttct atatctactg atactaaagt atcaatctta ctatttatta gagaattatt
    17341 gtttatgtta gatttaactt gagatatata tgaagcgttg aaaccttgat atttataagc
    17401 cataggtcca tatatacata gctttatagc ctcaaatatt gtagatttac cagcaccatt
    17461 tttaccacct atcaatataa tatttttgtc actagtagta tttagattga atgttgtttc
    17521 ttcttcataa gatctgaaat tttttaatac aagtttattt attttcatat tttaactcct
    17581 tgttgccttc ttcttcaatc ttttcaataa tatcttgatg aagccactgt tgatttaata
    17641 ttctttctat ggaagttttt aatttagtat tattactaaa atatttatat ttatttgtat
    17701 ctatgattaa tttattaaat aaatcaatat ttatatcata ctcactacat ttttcagata
    17761 taatatttaa agtaaggtca tcaaatactg gttttttata ttcagaccat ggtaggtttt
    17821 tacctacaac ttccttatat atttttgata atatattacc agttaagtct tcttcgttat
    17881 cccaaatctc atctatagct ttaagttctc ctaattgtat aagttgtaaa tcaggataaa
    17941 atttttgcat ttcaagttga gtttctaaaa gttttcttaa aatagtttgc cttgcttcaa
    18001 atgtaaatgg tccaaacatg attttaccat cttttttaat aacagagcca tttcttttat
    18061 gttttttacg atttttaggt ttatctctct cagaaattag ccaacttctg aattccaaaa
    18121 gtggctttaa ttcatcatga ccagattcaa taaatccgtt taatgatttg tcttctttta
    18181 caacagtaca aatccaacat ccaaacctac tatttccaca gctactttta gcactagctt
    18241 catctgctat aaatgggcat tcatctgagt caccagaacc tttcatatac atctgaaata
    18301 attccatagc atcagttccc catgaggtag atggagatgg tccaaattca ccaccaaaat
    18361 ctatgaaatt atcattttga tgatagagta catcccaaac atctgctgta ctaaaattga
    18421 ctataggggt atacacataa gctaacttat ttttacctct taaggtttca tgtggggtaa
    18481 gaaggtaacc ctctatctct cttttttcga ttctcgattt tctagcagaa ctttcttctt
    18541 tacgaacgcc aagcagtaca ataacatctt tttgttcaag tttttctttt ataaatttat
    18601 ttgatggttt tatcttaagc ctttcagtac accaacgata tttaatagac tttggagtag
    18661 ggtaacctct accaattata ttggcccaaa aactatcatt aagttctggg tatacaatct
    18721 gtgcacttat aggtaaatca tgttcagtag cactttcatt tatcttgtct atattatttt
    18781 ttagataatc aagtattatt ggattttcta taagtgtatc agatgagatt acataaatct
    18841 ctttatgtct tttttctttg ggtagtcttt taagcattct aaatgtaagt tcaactacac
    18901 aagaactatc ttttccagaa ctatatccga ttatccaagg tctatcatca ttaagatata
    18961 cggcctgcat ttcatcatat aaattttcta aattgttgtt atctaggtaa ttaacagcca
    19021 tatattaagt atcctttcta taagagtata gcgaagatct ttacataata ctcctatttt
    19081 aatttatata taattatatc acaatatata tttagagaat agattagttt atatttacat
    19141 aagtacaata aaatataaat ttaattaaat gtagaactgt tatcatttta agataatata
    19201 tttaaaaatt agagaataag aatgtacata cttgaatctc ataaatgtat ataaagatat
    19261 gtatgaataa aaatagcagc tacttagaat agttacacta tttaagattt attatattat
    19321 agattgacta aacaatagat atttattaat gactcaattt ataaacttta aaagttatat
    19381 cccaataata ccccaaccac aaaaataaac aataaaaaat aaccaaaaaa atcagtctaa
    19441 tatcataact aaatagctat atacctacat tcacaaaaac caacaaaaca atcaaataac
    19501 cacttataga ctcccctcgt ctccaccatt gaaatccacg aatacctata tccaattgga
    19561 tataggtatt tttatacatt tttagtttaa atattattga taaatacatt taaaaagttt
    19621 taacctaaag tgaagaatct aaataaaaat aaaatattag gagaggttat cattacaata
    19681 acagcttgtg atgatgaaaa agaaatacaa atcgtaataa aaaatcaagt tgataatata
    19741 ttaaaaaata aaaacaaaga atatcgaatt aaaaaaatat agctcaaaag aagaaccatt
    19801 acaaagttaa ttgagaggat acactactct tagatataaa aatgccagaa ctaaatagta
    19861 tagatatcgc aagaaacata agaaaagtag ataataatat ttataacatc tctaataaat
    19921 tatgtacagg agagatatga agtaagagat tattgatact tattaaagcc aataaatttt
    19981 caagaactag aaaaacacat attaacatat atcaaaaaaa ttgaaaaaaa taaaaataag
    20041 tctaacacat acaaaatcta ctctagcaaa aaaatagata gaagttcaaa aaaagaacat
    20101 gctaatacat acaaaaaata aaacttttga tgctatatgt atcctagaaa aaatagaaaa
    20161 agatttaaat atagaggaac ttgtaagatg tcataaaagt tatataatta acttaaatta
    20221 tgcagaaaat ataaagtcaa atactgcaat attagatagt caagaagaag tacctattag
    20281 tagatataga tataaagata taaaagaggg gtttctaaaa tttattggtg atagaatatg
    20341 ctaaaccata taaataaaat attattaata ttatcattgt ttacaccaat aatgatacta
    20401 aaaagtatat taacttacga taaagataca gataagacta agaaaatatc tttttttact
    20461 gtattattag cttatcttat aactaaaatc attatattat ttaacgttga taagacccat
    20521 aattataata tgaagaaaaa tctatatgat ataatctatt atttgatatt tattatttgg
    20581 gaacttacta taattatttt tataagatag gaattgttaa atatatagtt tcatttttct
    20641 tatctgacgt atatcaccct ttaataaaag atgttatatc tataaattta ttttttgtag
    20701 ttacaagtaa tgtaatatca tcagaggaag ctctattagt gtttagttat gataatgcta
    20761 aagtagatat atactattat cttataataa tagttatata gtagcttgtg ctatatttaa
    20821 atttattaat aaaagattgg gactagataa agataataaa ataaactata tatacttatc
    20881 tgttgcttta ataacaaatt tatttactat attaataatt tatataaata aaaaaatgta
    20941 tcgatttggt gggtattagg aaatatatat agttgggtat attgtgatac ctaggttaat
    21001 actagctagt agcttagtaa ttattatagt gtttataaaa ataattaagg aaaataagtt
    21061 aaaattgcaa aatgaagtaa taaaaaataa gttagatatg cagtattctc attatctaag
    21121 tattcaagaa tcacacgcta aagttaagaa gctttatcat gatataaata atcatatata
    21181 ttgtatagaa aatctcaaat ataaaaaagg aaaattgatg ggtatgtaaa tagtttaaaa
    21241 gattaaatta aagaatttaa atcaatttac aatacaggta atgttatatt ggatataata
    21301 ataaatgaaa aaagtgatgt aagtgaaaaa agaaaaatta aattcatttg tgatatcaat
    21361 ttttccaaag tgaattttat aaaacaaata gatgtatcta atatatttgc aaatacttag
    21421 ataatgcaat agaagcttgc gataagatac atgataaaag tattgataaa tatatacaaa
    21481 taaaaggaac tatctcaaag tcctatttcg taattaaatg tgagaatagt aaaataaatt
    21541 caattagaaa gaataaaagt ttattattaa cagataaaaa agataaactt gtacatggaa
    21601 tagggattta aagcatcaaa tcttctataa aaaaatatag aggagattta tcatttgaag
    21661 ataaaaaaga caaatttata ttgaatattt atataccatt aaatcaaaat tttgatagtt
    21721 gggtcgatta acctaccagt tggggaacat atattgatac taaacatata gggatgttat
    21781 cttttaatag aaaaagatag cgtctttttt ttatgagaaa taacgagttt tcaatatata
    21841 aggaggatta tatgaagata aaaaaattac aataactatg gttatagcta taagcttaac
    21901 actaggttta ataacaggat gcacaaataa gatttcagat acaaatgaaa aaatatatac
    21961 tattgaacag atttctagta tcaagaagac ttgtcaaaga aaatatcaga atcaatagaa
    22021 aatagtggtc ttagggtagc tgaaaataaa tcagatggaa gttttgtttt gtctttggga
    22081 aacttggagt atacaaaaga acaacctagc caagttttac attattcaat aactaaggac
    22141 aagaaggata cgaaggaaat attatcaatt caatgtgtta aagatttttc ttataatgaa
    22201 aagctgtcag aagatgataa attcataatg gccatttata acatatagat cattgattca
    22261 tatagaaata agtgagaaag aattttttag aaaaattgaa gaagtatttg ataaaggtga
    22321 agaaaatgta gaggttgata atttgggaga tataaaaatt caagttaaga aatttgatga
    22381 taaaactaag cctttagaat taaaacttat taaagaattt aaattgaagt aggaagattc
    22441 actatgagaa aatacaaagc tattttatta actttaatta taagcattat agccataata
    22501 ggatttatta tatacaacaa ctattttaga aaatggaatg aagctgaaaa atatatagat
    22561 aaatatatga catatcaagg agtttcaagt gatgatatag agcgtattac aaaagaaaag
    22621 tatacaaaag agaattagga tgggatactt tataaatcat tttacaaaaa ctatccaggt
    22681 tataaatact aatattttta taatggtgat tattatgcac tacatgtaaa taaggtgata
    22741 ctgcaagttt atcatgagga agatggtagt aagcttcaaa aaataatgaa gaattaaaag
    22801 atttaaaata tccaccaatc tacttaacag atgagttgga taaataattt atagtaaaat
    22861 aggaggatta tatggggatt tacttaaaaa tgtcactagc atatttaaag aaaaataaac
    22921 ttagaacatt acttttaata ataggagtta tgttaggtgt tatgttgata tttggaccta
    22981 gtgttataaa agattcacaa aatgaaaaca atgtagtagc aatacatgaa ctttacagtg
    23041 gataccatgt agagtttagt gatttgacac ttgatgatgc taaaaaatta gaaactgatg
    23101 aaaaagtatc aaagggtaat tcggtacaaa atctaggacg tatttcagat aaaaaaggaa
    23161 actcatttat attaacttca tcaaacgaag agtatctaaa aagtagatac aacaaaataa
    23221 tagaaggtag actacctaaa aacaacaatg aaatagtatt agagaaaaaa gcactagaag
    23281 caatgaattt aagtgaagga gtaggatcta cattaaattt aacaataaaa aagaactata
    23341 aagatactaa cggaagtaat caattatttt ctataaataa agaatttaaa atagtaggag
    23401 ttatggaaaa accaaaaggg tactatgatg tggtttggca atacgaagca gtaacttatg
    23461 gcaatgatga aacaaacaac attataccta atgatgcgat tagttataat agtatattaa
    23521 gttttaaaag tggatggaga aatattgaag gtgaatgtga ttatcttatg aaaaaatata
    23581 agttaggaca aaaaagcttt ctaccaaatg tacctcttgt aagggaactt cgttatgtag
    23641 aagatgataa gagtgatccg aatgttttta aaagaaatgt tttaataact acagtatcta
    23701 taattttcat atttaatatt ttcaatatta cactaaatca atcagtaaaa gaaatgggac
    23761 tgtttagact gatgggtgca aagaaaagaa acgtaaggtg tatgataatc tatcaagcat
    23821 taattataac aataataggt atactacttg ggttagtagc tggggttaca tattcatata
    23881 taggaattag taattataac gaagttttat acagtgaagc tggtcttaac cctaaattat
    23941 atataaataa tgaaatagtt ataaaagcta tattggttgg aataatttct gtttttatat
    24001 cttgtattat accaactttt aaaatcggca agatatcacc tattgaatca ataataaata
    24061 cagacaaaat taaaaatcac agaagtagac ttggaataga cagactagta agcaaaatat
    24121 ttggatttta tggatttatg ggacttaaaa atattggaag aaataaggtt agagctgcta
    24181 tatctatgtt gtctattgct ttaggaggat atatattcat tactacattc tcaagtatgc
    24241 aagaagaggt caacagtaaa attgaagata tgcaaaatag atataatata acaatgcaat
    24301 ttggagtaaa tgcagacccg caaatatcaa aatacacgga tagtgatgta gagaatatag
    24361 aaaaaattaa gggtgttaaa agtatacata aaattcaaat aacaaatgga atgtttactt
    24421 ttaataataa ggatataaac aaagaattta caacctataa tggagtagaa aaaaaagaga
    24481 taatggaaga taaattagtt ttaaagcttt atgatgatta tatagatgaa aagttaaatg
    24541 actttgttga agaaggtagc ttagatgata ttaaaaagga cactgatgga tatccaaatg
    24601 tagcagtata taattatttt tatgatatag ttgatgatca tactataaag cctatattca
    24661 aagaattaaa tataggagac ataataactg taaaaattcc tgttgaagaa aataatacaa
    24721 ttgtttataa agagatgaag gtaagagtgg ctgtaatttt aaaggatgaa tggattgcta
    24781 tgggagatgg cgattttatg ccagatctag aaattataac aagtaatatt cactctaaaa
    24841 acataacagg agaacaaaaa tacactcaat taggcataaa tttagaaaat ccatatgatg
    24901 agattgttaa taatgagata cagaaaattt caagaagtat accagggtct ctatttaata
    24961 gtagattaag ttatcatgaa atgtcagaaa gtatatataa aagttacatt aaatcacaaa
    25021 tagcaataat tgcactagtt ttaataatag catcaattaa tattttctgt actataagaa
    25081 caaatctact aattagaaaa aaagaaattt caacgcttag agcattaggt gttagtctta
    25141 aaaatatgaa aaaaatgctt atatatgaag cattagcata tgcagttttt agctttataa
    25201 tagctatgat tccatcattt ataaatctag ttaaatttac aaattggaat aatgatgcgt
    25261 atataaacta tggaatagag aattttatgt cttttacatt cccaattaag gaatctttac
    25321 tattctttgc tatatctgta tttgtatgtt taatagcagt agttgtaagt aatagagatt
    25381 ttgaaagtat gaatattatt gaaggtataa aagagaatga ataatttggg aggtaaatgt
    25441 atgaagatgt taaaagttat agatattaaa aaaatatatg gaaaaggaga aaatgaaata
    25501 aaggctgttg atggaattac tttagagata gaaccccata aatttagtgc aataattgga
    25561 caaagtggtt ctggaaaaag cacattactt cactgtatgg cagggcttga taaaccaact
    25621 ttaggtaatg tatttatgga taatttagat ttatatactt taagtgatga aaagctatct
    25681 aatcttagaa gtaaagaatt tgggtttata ttccaaaact ataatctaat acctgttatc
    25741 aatgtttatg ataatatagt tcttcctatt ttaattgcta aaggaaagat agataataat
    25801 tatattaatg atttaataac taagttagga ttagaaagtc agattaataa atttcctaat
    25861 gaattatcag gtggtcaaca acaaagagtt gcaatagcaa gatcacttgc caataagcca
    25921 tcaataattt ttgcagatga acctactgga aatttagaca gtaaaacaac taatgaggtg
    25981 atgaatttac taaagtattg tgtaaatgaa tacaagcaga cgttggttat gataactcat
    26041 aatgatgaaa tagctaagat ggctgattgt ataataacta ttagtgatgg taaagtcata
    26101 taaaatgtat tgtataaagg tttaatcgtg ggtattattc ttgtgattct tctccactat
    26161 ttaaatccac gaaataagga ctgtcgaatg agtaatttta aattgctgtg cgacagttct
    26221 ttttttactt gcttttcatt aatttatatt tatgcaaaat ttgagcttga aaacggtcat
    26281 aagaaataaa ggtataaaaa taccatttta aaatagaata atttacaaag tgtaagatta
    26341 aaaaatagtt ttgagaggat gaatatacat actacattta ttaatgatta tcttatttgt
    26401 gaaacttaga aatactatag gctaacacta caggtataaa ctctgaaaga atatcttgat
    26461 tgcctctgat tagaattctt ttaaagttca tactatgttt tatttgggtg aaagctcctt
    26521 atgcctgaat acttctattc attctaagtt cacatccttg tgtaccagtg attctttcta
    26581 aattatctta atgccaaaat cttgttcgca tttcaaaata aagtcaggta gctacttcaa
    26641 cattttagtt atatttcttc aatagtttgt ctccaaacaa aggtacatct attagcaaca
    26701 gatttaattt tatttatatc aataaataat atatactttg aaacttcatt aatatcacca
    26761 agataattta taagttaaac tattatatat tatcttcact aactacatcc tccatagttt
    26821 tacactttct taattcagct tggtaatcta aatctgtaat aattatttct ctttgatttt
    26881 tcatttcttt gcctacaaaa gtttaatatg aatattattc tatacttacc aattttacgt
    26941 tcaaaaaaga ctgtagataa gtctgcattt acacaaacct acttataggt ctcttttttg
    27001 aaattaattt agcatgaact atagtaagag catctttaaa ttcatattta caagtataca
    27061 aagttataat tttatctgaa atatctacct ttatatcaga tttgtgtact gatttttagg
    27121 ttatataatt caaagaatat ttaaactcat cattattatt aaagtgtata cttaaataat
    27181 ctctgttaat taagtcagca gtatatactg aaaaaatttc ataagtataa gtttgtactt
    27241 tataatttat ttctactaaa ttattttctt tgaaaaatac ttcatcagta tagttttcta
    27301 gctgaccaaa catagtttta tttttcatat aatgaccata gactattaaa ctcttatcat
    27361 tttcaaaatt atttctataa tccatgaaaa tactacctaa aggaagataa tttttataaa
    27421 aatcatgagt taggtagaaa tcattgttat atccttgtac tacaggatag tctatattta
    27481 cgttgtttat tttaagccag aatctataat cattattttt atcataaagt tcttgatgtt
    27541 tgctattatt gatagtgttt tctctgagtt ccgtatatac ttcatcagct ttttatattc
    27601 agataatttt atgtaaatcg aaaggctaga gaaagttagc gtaataatgc aaataatatt
    27661 tattaatatt tttactagtt ttttcaatta attacccctt gtattattat ataaaagatt
    27721 aaataaattt tatataatta aaatttttat tgtagttatt tagcaaataa tgaatactta
    27781 taatatataa ggttgaaaaa aactgtatat tcattgacaa atataagttt taagtatata
    27841 ttaaaaatta ttagagtgta tataaggatg tatacagtgt atattaagaa ttattagagt
    27901 gtatataagg atgtatacag tgtatattaa aaattattaa ggggaggggg aatttatgca
    27961 acaaaaatgt aaaaagaaag cactatcaat gattttaagt atctcaatgg gacttggatc
    28021 agtagcatca tttaatgcgt caaatacttt cgcagatact atagaagaaa gtactaatgc
    28081 aggaaatgca gaaggagata ctaatgcagg aaatgcagga ggggatgcta atgcaggaaa
    28141 tgcagaaggg gatgctaatg caggaaatgc aggaggggat gctaatgcag gaaatgcagg
    28201 aggagatact aatgcaggaa atgcagaagg agatgctaat gcaggaaatg caggaggaga
    28261 tgctaatgca ggaaatgcag aaggagatgc taatgcagga aatgcagaag aagattctaa
    28321 tgcaggaaat gcagaagaag attctaatgc aggaaatgca gaaggagata tgaatgcatt
    28381 agttgtggaa gaagccactg cagaagatcc tacatctgta ggagacttta aaattagtgg
    28441 tggagaaata aatgtcgatt ttaaatttgc aagtggcgtt ttaactattc ttagtggaaa
    28501 acaaatgaca attcaaaata ataatccaaa tactccaaca acacatagga ttgttatacc
    28561 taaagatgta aaagctgaat taatatttga tggagtaaat attaaaactg catctaatag
    28621 tccatttact ttaacaccag ataaagatgg tggtgcatat gcacatgtta tattacaaga
    28681 tggtagtgaa aacaagctag agtcaggtga tgtatattat ccaggtatga gagcaggaaa
    28741 aggtactact ctaattattg atgattctgt tgtaaataga gatattgaag gcgagtttat
    28801 agttcctgag ggtggaaaaa ttcctagaga tgtaactcta gaaaatggag acaagttaaa
    28861 aaaaggagat cgccttacac tactagatag taataataga ggaagtttaa aagttgttgg
    28921 aaattattat tctgcaggta ttggcggtgg aaatactgaa agtggaggaa atattattat
    28981 taatggtggt gctataactg ctataggtca agaatcgagt cgtaatacag gatatggagc
    29041 tggaataggt ggaggcggta atggtagtgg tggagatatc acaatcaatg gtggtactat
    29101 aactgctaaa ggtgcatacc atggagctgg aataggtgga ggatactata caacaacaaa
    29161 gaatgcatta agtccctcag tagtagatcc tagcacaggt tctggttata gtgggaatat
    29221 tacaattaat ggtggacttt cctattcata tggaggtgca catggtagtg catttgggga
    29281 tggatgtgtt aatccaggaa caaatagagg atatcgtata cttgtaactg gaggaacgat
    29341 tttaccttat atgacaggag tgggagattg gatttttgac ctaagtgcta caacgggaga
    29401 tgttatagta acaggtggtt cattaaaagc aacaacattc aaaagtttag gtggagcagt
    29461 tgcatacggt gatttagaaa agaaaacaaa agtttttatg aataaaatat ctctaacgta
    29521 tttagggcaa gataaagtta gtactacact agttgatgat tttaaaatgc taattgatgg
    29581 aaaaatttat ccttatggag cacctagtta tacagatgct caagggattc tttacttatg
    29641 gttctctgat aaatttactg gatctgaagt atctgttaat ttagttgtta tagataaaat
    29701 tactggagaa gttctaaaac cagatgattt ttatattaaa gatataggtt caggttctca
    29761 atttttaaag caatatgaag aatttactat tgatgatact ccaccatatt tgattattaa
    29821 aagatatgat ggattaccat ttgaagaaga cgtagaaaaa tcatttttag attggctatt
    29881 aaaagatggt ggtattccaa taactactcc taaaggtgaa aaactcacag ataaaaaatt
    29941 tatgactatt agttctcaac gtttaaatga ggaaacgatg gaaccagata taaatttagg
    30001 aagtgatgat cttacaaaac aagttgatgc tgggaaatat caattaagca ttacatcaac
    30061 acagttttcg agtatatatc cttttaagga tgcttattgg gggcatagag catactataa
    30121 ggcagaaatt attcctgctg atacagaaac ttcattagtt gtagaagagt ctaaagctaa
    30181 aactgatgtt tttaaaccaa cagatacgtt tacattaaat gttactattt caccagataa
    30241 gaaagaagga ccagattgtg cctctccaag aggttacgta caattctata ttaatggaaa
    30301 ggaatataaa gatccagtag aattaaaaac tcataataag ggtagtgaga gtcataatta
    30361 tagtactgca tctattgaat ggagaccttt agatagcaat catcatattt ttactactga
    30421 acaaactatt actgtaaaat atattggaga tgatataaat tacattgaag gtagtgagga
    30481 tgaaaagaag ttaaagttag atatgacaaa tgtagatgta gatggggatg gaataccgga
    30541 tataaatata gacactgatg gtgatggaag gccagatatc aatatagata cgagtggtga
    30601 ttggaagcca gatattaaca tagatactga taatacaggt gaatggaagc ctagtacaga
    30661 aggtggaaat ggagatggta tttggaaacc tgataaaaat atagatacca atggagatgg
    30721 aaaccctgat acagattata atcgtccagc aatagataca gataatgatg gagtagatga
    30781 ttattggaag cctgataaaa atgtagatac tggctcagga ggttatgata caggtaatcc
    30841 aaatctaaat aagccagatc cagataatgg aggaaatagc aagccggatc cag
//
LOCUS       DAEOTL010000042        30707 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEOTL010000042 DAEOTL010000000
VERSION     DAEOTL010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.042"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            126..2027
                     /locus_tag="KRH82_002280"
     CDS             126..2027
                     /locus_tag="KRH82_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8655554.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2030..3073
                     /gene="ypdE"
                     /locus_tag="KRH82_002281"
     CDS             2030..3073
                     /gene="ypdE"
                     /locus_tag="KRH82_002281"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBG8655555.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3088..3393
                     /locus_tag="KRH82_002282"
     CDS             3088..3393
                     /locus_tag="KRH82_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8655556.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3490..3825
                     /locus_tag="KRH82_002283"
     CDS             3490..3825
                     /locus_tag="KRH82_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8655557.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3857..5179
                     /locus_tag="KRH82_002284"
     CDS             3857..5179
                     /locus_tag="KRH82_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8655558.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5189..6259
                     /locus_tag="KRH82_002285"
     CDS             5189..6259
                     /locus_tag="KRH82_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8655559.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6264..7451
                     /locus_tag="KRH82_002286"
     CDS             6264..7451
                     /locus_tag="KRH82_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8655560.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7648..8520)
                     /locus_tag="KRH82_002287"
     CDS             complement(7648..8520)
                     /locus_tag="KRH82_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBG8655561.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNVLWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8914..9105)
                     /locus_tag="KRH82_002288"
     CDS             complement(8914..9105)
                     /locus_tag="KRH82_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655562.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9325..10371
                     /gene="cobT"
                     /locus_tag="KRH82_002289"
     CDS             9325..10371
                     /gene="cobT"
                     /locus_tag="KRH82_002289"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBG8655563.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10403..10963
                     /gene="cobU"
                     /locus_tag="KRH82_002290"
     CDS             10403..10963
                     /gene="cobU"
                     /locus_tag="KRH82_002290"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBG8655564.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10973..11746
                     /gene="cobS"
                     /locus_tag="KRH82_002291"
     CDS             10973..11746
                     /gene="cobS"
                     /locus_tag="KRH82_002291"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBG8655565.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11766..12380
                     /locus_tag="KRH82_002292"
     CDS             11766..12380
                     /locus_tag="KRH82_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBG8655566.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12447..12626
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12756..14255
                     /locus_tag="KRH82_002293"
     CDS             12756..14255
                     /locus_tag="KRH82_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBG8655567.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSSLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14294..15670
                     /locus_tag="KRH82_002294"
     CDS             14294..15670
                     /locus_tag="KRH82_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBG8655568.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            15671..16642
                     /locus_tag="KRH82_002295"
     CDS             15671..16642
                     /locus_tag="KRH82_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBG8655569.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYVIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16674..17744
                     /locus_tag="KRH82_002296"
     CDS             16674..17744
                     /locus_tag="KRH82_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8655570.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17746..18633
                     /locus_tag="KRH82_002297"
     CDS             17746..18633
                     /locus_tag="KRH82_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBG8655571.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKECLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            18621..19253
                     /locus_tag="KRH82_002298"
     CDS             18621..19253
                     /locus_tag="KRH82_002298"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBG8655572.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19262..20488
                     /locus_tag="KRH82_002299"
     CDS             19262..20488
                     /locus_tag="KRH82_002299"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBG8655573.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20485..21093
                     /locus_tag="KRH82_002300"
     CDS             20485..21093
                     /locus_tag="KRH82_002300"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBG8655574.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRIDNFDMNVVVILDEE"
     gene            21083..21658
                     /locus_tag="KRH82_002301"
     CDS             21083..21658
                     /locus_tag="KRH82_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBG8655575.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21651..22403
                     /locus_tag="KRH82_002302"
     CDS             21651..22403
                     /locus_tag="KRH82_002302"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBG8655576.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22387..23508
                     /gene="cbiG"
                     /locus_tag="KRH82_002303"
     CDS             22387..23508
                     /gene="cbiG"
                     /locus_tag="KRH82_002303"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBG8655577.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23505..24230
                     /gene="cobJ"
                     /locus_tag="KRH82_002304"
     CDS             23505..24230
                     /gene="cobJ"
                     /locus_tag="KRH82_002304"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBG8655578.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKSGDTPVGVVKDVGREKEEKLVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24227..24979
                     /gene="cobK"
                     /locus_tag="KRH82_002305"
     CDS             24227..24979
                     /gene="cobK"
                     /locus_tag="KRH82_002305"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBG8655579.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            24998..26476
                     /locus_tag="KRH82_002306"
     CDS             24998..26476
                     /locus_tag="KRH82_002306"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBG8655580.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26506..27411
                     /gene="hemC"
                     /locus_tag="KRH82_002307"
     CDS             26506..27411
                     /gene="hemC"
                     /locus_tag="KRH82_002307"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBG8655581.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27401..28900
                     /gene="cobA"
                     /locus_tag="KRH82_002308"
     CDS             27401..28900
                     /gene="cobA"
                     /locus_tag="KRH82_002308"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBG8655582.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28917..29882
                     /gene="hemB"
                     /locus_tag="KRH82_002309"
     CDS             28917..29882
                     /gene="hemB"
                     /locus_tag="KRH82_002309"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBG8655583.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30035..30613
                     /locus_tag="KRH82_002310"
     CDS             30035..30613
                     /locus_tag="KRH82_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBG8655584.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12447 a         3060 c         5669 g         9531 t
ORIGIN      
        1 aaattgtgga attaaaatat actaggatat aaaattctta aataaaaaga aaagattgtt
       61 tttataaaaa atatttttta taccacttta aaaaacacaa taataacact gagggaggtg
      121 gggatatgag agaacgcatt attcttgaaa cattaaaaaa tagtagtggt tatctaaaca
      181 tagattattt tgcagataag ttgggggtat ctactcgaac tatcagaaat gaaataaaaa
      241 agatagaaac tataaaagaa tgtaatggtt ttaaattaga atataagtct aaattaggat
      301 atattctaaa tattaaagac caagataaat tcgagcatta tctaagaaac ttaccctcag
      361 atttagttga aaatccagaa caacggttgg agtctataat agtagagctt ttagtaaatg
      421 aaggttataa aactatagaa cagttaagta aaaaatttct agtaagttca tcccaaataa
      481 aaaatgattt aaaaaagata gatgaaaaga taaaggatac agaattaaaa ctagagcgaa
      541 aggctcatta tggaattaaa atagaaggtt ctataaaaga aattcaaagt atattggtgg
      601 atagttattt tagagggaat agaaatataa cagagtacag gaataagttt atagataatt
      661 taaaattagc taatattaga agtacaataa aaaatgtact taatgaacat gatttagaag
      721 caaatttaac agaacttgag gaaatattag cacaaattat tatattgtat ataagagtta
      781 gtatgagagt agtgggaaat gctagcgatt taaaattata tacagaagat ttaattatag
      841 ataaattatt agataaaatt tttagagata aaaaatataa ccttaattat gatgaaaagt
      901 attatttaaa ggagcttata aaactaaaga ctaaagataa gaaagccact ataaagaata
      961 ttgataagaa taaacttcaa gatattatgt tcgaattttt tagagagata gataaaaaat
     1021 ataactctaa ttttttagaa gataaagagt tttttaactt attttactta catattgcat
     1081 gtttaataga acgtataaag aagaaccaca agataataaa tcctttttca gttaaaataa
     1141 gtcaacagta tccaactgtt tttaacttat ctattcaatt ttcaaaaatc atagaaaatg
     1201 agtatcatat aaaaataagt caagatgaaa tagggtttat agctactcac attgctgttc
     1261 cttttgaaaa gagagaagaa gctaatttta ataaaaaata taaaatagca ataatatgct
     1321 cttctggtgg aggtagtgca tttttgataa atttaagact taaagaaatt tttccaaatg
     1381 ctgagataag aaatttttca ttactagaag aaaaagctgt aatagaattt gcaccagatt
     1441 tgattttttc aataacaaat cttttatttg aaataaatgc tccagttata cttataaatg
     1501 aaattttaga cgaattggat tatttagata ttaaagaaag tgttagattt gcagaccata
     1561 taggaaatat atcaagccca aaacaatata tattaggtct atttgataag aatcacttta
     1621 ggtgtataaa agataaagct aagtataagg atatccttga tagtatgtca aaatgtatag
     1681 ttgacgaggg agcttgttct ccaacctatc ccaaagatgt atgggaaaga gaaagctatt
     1741 tgagtactat ttatacaaat ggggtggcta tacctcatcc aatcgagatg acaggaaaca
     1801 aaaatataat atcagtagct ttgatacaaa ctgatattat ttatgaaaat agggtgccta
     1861 aaattatttt catgatttca ttaataaagg gaaatttaga acttcataag caaatatcta
     1921 aatatttaag taagattatg gcaaataagg atatggtaga catgctaaat aagtcacaat
     1981 cttatgaaga gtttatgtat aagttaaaaa tctatctggg aggttagaca tgaatataga
     2041 gttttttaag aggttgtcag aagcagatgg tatagcatct aatgaagaag aggttagaca
     2101 tgttttattg gaagaactaa aagcttatag tgataaaatt atctgtgatg ggctagggag
     2161 tatcatcttt tctaaaataa aagatgagag tgcaccaaac gtaatgattt gtgctcatat
     2221 ggatgaagtt ggatttatgg tgagaagtat agacaaactt ggtatgattc acttaataac
     2281 aataggagga gtaaaacctc ttgcacagtt tgtacaaaaa gttagaatta caacaaaaga
     2341 agggaagaaa atccccgctg tcataaatgc tacatataat aatggtaagg ctgaaaatat
     2401 atatgcagat attggagcat atacagaaga agatgtatat aacctaggga ttaatgttgg
     2461 ggatatggta acatatacaa caagctttga ggaatttact ttaccagacc gattagtggg
     2521 aaaggctttt gatgatagga taggatgttt tgtgatggga gaagttttaa aagaacttag
     2581 gaaagaaaat ctaaattgta atattcactt tgcggctaca agtagtgaag aggttggaat
     2641 aaggggagca aagacatcaa cacagctaat aaatccagat atagtatttg taatagatgt
     2701 agcatgtgct aaaaatgagt ttgtgagaga ctatacaaat cagaaacaaa ttgataaagg
     2761 tgtaatgcta atgcatagag ataggactct agtccctagt agaaaaatga tagattatgt
     2821 aatggaaatt gctgataaaa ataatatacc acttcaacat gatatgtttg aatcaggtgg
     2881 gactgatgga ggagaagcac atctcgtaaa tgaagggaaa ccttgtgtag taacttgtgt
     2941 accagttaga tatggtcatt gtgcattttc aatagtaagt aataaagatt tggagaacat
     3001 tataagattg tatacacagt taattttaaa ttttgatgaa gaacaatata aacatataag
     3061 aaattttatc taaaggagaa taagaaaatg tcaacagaag tacaaataat ggaacttata
     3121 tcaactgcag gagagagtaa atcgaaagct tttgaggctt taaaaaaagt gaagtcaaaa
     3181 gattttaaag gagcaaaatt gttaatagag gaagctcgta aaatagatat tgaagctcac
     3241 aggatacaaa cagaattaat aactcaagat ttaaatgaag atgttgaaag tccagcaatg
     3301 agtcttttaa tggtacatgc tcaagaccac tatatgactt ctcagctagc aaaagacttg
     3361 atagaggctt tgatatattg tctcgataag taattgtaat gtagaaatag attatttatg
     3421 taaaaattct tttaaaagtt tagatgcttt taagagataa taaaaataca aactttagga
     3481 ggaattatta tgaaaatatt attatgttgt gcaggtggat tttctactaa tatgttaatg
     3541 caaaatatga aaaaggtggt aaaagagagt gctaaactca atgaaaaaga ttttgagttt
     3601 acagctatac cagcagattc aatagaaagt gaagttgatg attgggatat agtacttata
     3661 ggtcctcaaa tagctcacaa aatagacttc ttaaaaggaa tattagagcc aaaaaataag
     3721 ccttttgcag taatagataa agatgtatat ggaaaaatgg atggagctac agttatgaag
     3781 ttggcattaa taacttataa gaaacatcaa ttagctcaag gataataaaa ataatgaggg
     3841 aaaagggaga ttagatatgt tttcaaaatt tgaagcattt atgaatagag tatttatgcc
     3901 tttagctcat aaggttgaca atcaacgtca ccttggttct ataaaggctg gtatggttgc
     3961 tatgacacca ttcacaatat taggaagtat atttgcaata cttccagcac ttccaaatat
     4021 gcttggagaa aataatccaa taagcaaatt catacttaac aattcagcaa tattggattt
     4081 accagtaagt ctttccatag gtttaatagg attatatgct tgtatgtgta ttgcttttaa
     4141 tctggggaac tactataaat tatatatacc aggttgtgtt gcactatcaa ctttttcctt
     4201 tttattccta gtagcctcat ttacaccaga tggagcttta gaaataggaa atttaggagc
     4261 taaagggcta tttacaggta tgatagcagg gcttggttct gtggagttat ataatttttg
     4321 taataagaag aatatcacaa taaaaatgcc agaaaatgta cctgattttg tatctaggtc
     4381 ttttgaatta atacctacta ctataatagt ttgtggaact tttatagttg ctcgttttat
     4441 ttcattaaaa gtatttggag aattacctcc acagatactt actcaatttt tatctccatt
     4501 agtaggaagt atggataacc catggtcagt tcttgcactt aactttgcta tatgtactat
     4561 attctttttt ggaatacatt catcagtatt tagtcctata actagaccta taatgattac
     4621 atttatagct gaaaacatag cagctatgca agctggagaa acaatacctc atttctttac
     4681 agcaggagct tcaagtgcat tctttggatt tacaggatgt ggaattagta taggttgtgt
     4741 aattgcatgt atgttatcaa aaaatgcttc ctataagaag attggacgtg tatcattatt
     4801 ccctgcatta tttgggataa atgaaccaat attatttgga gcaccgataa tattaaatcc
     4861 aataatgttt ataccacatg tatttggtgg agctataata ggtacactac caatgttttt
     4921 tatgcactgg ggatggttag caaagccagt atttgaccct ccatatgtag gggtattctt
     4981 agaaggattt ttaactaatg gagattggca ttctatatta gcaaatgcat tgcaattagt
     5041 attagcagtt ttattatatt ggccattctt taaaataatg gaacgtcaac aaaataataa
     5101 aaaacaaaaa gaagaaacta agaatatatt ctctaaagaa gaagaagact tattggatga
     5161 tttaggattg gatttctaat attttgttat gaataataca atggagagat tagtatcctt
     5221 aatctataaa agaggtgttg acgctctttt gattaaagca aaaaatacta aaagatatat
     5281 aggagcttta tcaggtagtg gtgtatatgt gcttgttact aaggataaaa attatcaaat
     5341 tctagatggc agatatattg atgaagcaga taaaaaaacg actggtttca taaaaaggat
     5401 tgtatctcaa ggttcttata taccaactat aattgagtta ttaaaagaat taaatataaa
     5461 aaagttagca atagaaaacc aagctatgag tatacaagag tatctttcac taaaaaatga
     5521 aggttttgaa atcaatttaa taacaaatga attatggaag ctaagggcta taaaatctaa
     5581 agaagaaatt gaacttatta aaaaggcttg tgaaattaca gatgaagtat ttgatgaggt
     5641 tatttctgaa attaaaaaag atatgactga gctagaagta tcagctctaa ttcagtatca
     5701 tgcattaaaa aaaggtgcaa gtggaatgtc ttttgaaaca atagtggtat caggagaaag
     5761 aggtgcaatg ccacatggaa gacctacaaa caaaaaattg aaagtgaatg aagctataac
     5821 aatagatttt ggtgttgttt atcaagggta tcaatcagac atgactcgta caatatctat
     5881 aggtaaacct cctaaaatta ttaaagagat atatgatgta gtattggaag cacaattatc
     5941 tgcaatagag tcaataaagg aaggaactag ggcaagtgat gttgacaaag tggctagaaa
     6001 aattatagat aaacatggat ttggcgaata ttttaatcat ggactgggtc atggtatagg
     6061 tcttggagat ggtgaagttc ccactttaaa tccaaatagt gaagatatat tagtggaagg
     6121 aatggtaatg tcttgtgagc caggtattta tattccaaat gtagggggag ttagaataga
     6181 agatgatatt gttataatag atggaaaagg tgttccactc aataagacat ccaaagagtt
     6241 tataatatta ggagagtaaa attatgaaat ataattttaa taaagtatta aatcgtaaag
     6301 aaggaaattg tagaaaatgg agcaaccatg tgattaaaga aaaatttggc ttaaatgaag
     6361 atgcaattcc tatggattta gctgatatcg attttgagtg tgctcctgct ataaaagaat
     6421 ctatcttaaa aagagcatca gtaggagatt atagttatac ttttatagga gatgacttct
     6481 atgatgctat tataaattgg aataaaagaa gatttgatgt atatatagaa aaggattgga
     6541 taaaattaac ttttggtact gtttcaaccc ttcattatat agtccaagca tatactaaag
     6601 aaggagaggg tgtattgata aatacacctg cttatgaccc ttttgcagag gctgtagtaa
     6661 ataataatag aaagttgtgt tgtagctcat taaaattaga taacaataga tattatttag
     6721 atttagagga tatggaaaat caaatgaaat acgagaatat aagattgctt atattctgta
     6781 gtccacaaaa tccatcaggt cgtatatgga caaaagaaga actatatcaa gtgtcagagt
     6841 tatgtttaaa gtataatgta attttggtaa gtgatgaaat tcatagagat ataatattta
     6901 aagattatag atttgtatct ttgtggaatg ctcatccaga aatttataaa aatagtataa
     6961 tctgtgtatc tcctaataaa ggcttcaact taggtggatt aaaaacatca tatgtattaa
     7021 taagagatgt aaaaattagg gagactttat tagaaaggct aaaaagtaat tcaataactt
     7081 ctccaaatgt atttgcaata ccagcaatag ttgcagcata taatgaaagc gaagaatggc
     7141 tagatgctat gactagttat gtagaggaga attttgaaat agtttatgat ttctttgaaa
     7201 ctaatatacc aaaagctaaa gtgatgaagt cagactcttc ttttttagcc tggatagatg
     7261 taagagaagt atttagaaat gaagaagaat ctaaagaatt ttttagacat gcaaacttaa
     7321 ctatggtagt tggaagttat tttgtgaaag atggagatgg atttattcgt attaatgtgg
     7381 ggtgtcctag agaaacatta aatgaggctc taaatagaat caaaaaaacg tatataagta
     7441 tgtattgtta aatcataaaa aaagtatcta tggtttatat aaaaacacat tatttagtta
     7501 tcaaatatta ctggaatttt gtattccagt aatatttttt gattaaggaa tattattgag
     7561 gaatattaaa taatattatt tcataccctt atattaactt atataaaaat attttattat
     7621 tttgggaacg ggttagctaa cctttatcta gtgtatattt atattgtaag aagcagtaaa
     7681 aacttttcct ttactaagtt tattaataaa cttcttatct ttataaattt tgttagaatt
     7741 tatactatca gcaagaccat accaaggttc tatacataaa aaaggagcag tagaattagt
     7801 ttcactataa taaggagtcc aaataccaac tagagggaaa tcttccatag atatagttac
     7861 atatttacta ccatcattat tacatataga cacttcatct atgttggtgt atatcaaagc
     7921 atcattcttg aatacttctg gatttaactg taagtttttt aattttccaa taggtattat
     7981 atcatctgta aaagaaccat ttaaattgat tttttctaca tcatttttac ttttaaactc
     8041 aaggtagtgt ttagaaaaat cattttgttc gtaaaaagga aggttgaatg caggatgtcc
     8101 acctatagaa aagaatatat ctttagaatc agtatttttt acaatccatt ctacctcaat
     8161 actattatca tttaatgtat agtttatgat tagctcaaaa gaatatggat acttctttaa
     8221 agtagattca ttatctgtta atttataagt tacaaatgta tctcctttat ctacaatctc
     8281 aaagtccata tctctagcaa acccatgttg agtcatgcta tataaatttt cttctattat
     8341 tgtttcatta tcaaaaagtt tacctactat agggaacaat ataggtgatt gtctacccca
     8401 atatttttta ttaccatccc aaagaacgtt tttgtcgtat tttttagaaa atattttagt
     8461 tagttcagca ccaaaactgc ttgattcgat aattaaattt tcattttgta atatattcat
     8521 ttaaaatctc ctttattata ttttatgagt atattatact ataaagtata aagattatta
     8581 aattttattt gatattatat ttgaaaggta gattttagta tattttgaaa attttgtttt
     8641 gaaaatttgg gattatttaa gaaattttgt attataaata gaaggaaata gataaattgt
     8701 atagaataaa atatattaag ataagttaat aatgttaaat gggaagtgag tttatggaaa
     8761 aaccaaatac aaaagttgtt aactttcaag agtataaaga cagaaaaaac caaagagaag
     8821 taaatagaga cgaactttta aagcttataa aaaaaattgt gacttcaaaa tagggagttg
     8881 ttaaactccc tattttaatg ggtttcataa taattaagac attctaagtc catctatata
     8941 atctttgaat tgtgagaaat ctgattcact acttaattct atggtttctg aaccttccgt
     9001 ataaaaattc ttaagataga tagtataatt attatcaaca caatcatgat aaatacatct
     9061 atatccatct tcatacaaac tttttaattt agaaaaatca tccacaatat catctcctta
     9121 aagttctttt aaatatattt ttacaaaaag catctaattg tatgcaaatt gacaatgtaa
     9181 aataaaggaa atgaacataa aatgtagaat aatttttata tgtatgtaaa aataaaaaga
     9241 aaaagttgaa atttttagaa aataagagta ttttttatct aaaaagagag tttaaaaaat
     9301 aaaaaaatgt tgggaggata aaaaatgagt ttattagaaa gtatatcaaa aaacatatat
     9361 tccctagata actcttctat tgaaaaaaca aagcagagat tggataggct tatacatcca
     9421 actggaagct taggaaagat agaagatatt tgcatgcaat tagcaggaat atttggcaat
     9481 gaaaattttg acacaagtaa aaaggttata attgcttttg cgggagacca tggtgtatat
     9541 gaagaaggcg tagcacctga ccctcaaaat ataacaaaat tacagtttcc aaatttttcg
     9601 aaaggtctat gtggagttgg agtaataagt aaatttgtag gggcagatgt tgtagctgta
     9661 gatgtaggaa taaactgtga tgaaaaactg gatggggtat tagactacaa gataagaaaa
     9721 gggacatcaa atatggcaaa aggtccagct atgagtaaac aagaagcaat tagatgttta
     9781 gagataggta ttgaaatagc agagcagtgt atagaaaaag attataaggt tattggtatt
     9841 ggggagatgg gtatagcaaa tactactcca agtacagcaa taatatctgt aatttcaggg
     9901 tgtgacccgt tagaagttac tggtataggt gcaggtctta agaaagaaag actaaagcat
     9961 aaggctgaag taattagaaa ggctattgaa attaataatc caaatccaac tgatggagta
    10021 gatattttat ctaaagtagg aggatttgaa ataggctcaa tggcaggtgt tatattaggt
    10081 tgtagtgcta ataggattcc agtagtaatt gatgggttta tttcttatgc agcagcatta
    10141 attgcatata agataaatcc aaaaactaga gaatatatga tagcatctca tttatcagca
    10201 gaatcaggaa ctaaaagagc attagacata ttaaaattag accctctatt aaatatggat
    10261 atgagattag gtgagggaag tggagctgct ttagcatttg atataataga agcttcaaac
    10321 tatacttata aaaatatggc aacttttgat gaaattgaca tgggaagata aatataaaaa
    10381 tttaatatgt aggagtgttt tgatgagtaa aattattcta gtaacaggag gagctaggtc
    10441 agggaagagt aactttgcag aaaaactatg ttttgacaga aataataata cagcttatat
    10501 agcaacctct attccatttg atgatgaaat gaaagataga gtaaaaaaac atcaagagaa
    10561 tagacctaga aactggaata cttatgaaat atatgaagat atatattcca taattaagga
    10621 gatatataaa gaacatgaaa ctgttatact agattgtgta acattattag taaataatct
    10681 aatgtttgaa cacaatttaa atatagaaga atctagtcaa gaagaaataa acaaattaga
    10741 acaatacata aaagaacaag ttgtcaaact tattgaagaa atagaaaaaa caaatctata
    10801 ctttgtattt gtaacgaatg agttaggtat gggaattgtt cctgggaata aacttagtag
    10861 aatttatgct gatattgtag gtcgtataaa tcaatatata gcttcgaaaa gtaatgaagt
    10921 ttattttgta gttagtggca tagctatgaa gataaaggag tagtatgcaa ttatgaaaag
    10981 atttatttta atactacagt ttttgacaag gatacctata aaattaaatg taggatttga
    11041 tgatgaattt tataagtcaa tagtatattt tccacttgta ggttttgtca taggtatatt
    11101 atcctattta ataggatgga tttctatgct tttatttgaa ccatttatag cttctataat
    11161 aataactcta gctggtgtct taattactgg aggacttcat atagatggat taggagatac
    11221 atttgatgca atatatagtt atagagataa agaaaaaatg cttgaaataa tgaaagattc
    11281 aagattaggt acaaattcac ttctagcaat tatgtttgta cttttattaa aggttggatt
    11341 cgtttacgat ataataagta ataattcatt gtgggttata atttttatgc caatgattgc
    11401 aaggttagga gtaatgttat tgacatataa aactgtgaca ccaagagaaa aaggaatggg
    11461 aaatttattt ataggaaaat taactacaag tatgttaata actgctataa tatacacatt
    11521 attgatagtt gctcttatta ctaaatttat atttttatta cctaatatag tgttgattaa
    11581 agtattaggt tcgattatag tggtttttgt atttataata ttattcaaaa aacatattta
    11641 taaaaaaatt gatggagtaa caggagatat attaggctgt ggaatagaac tttcagagct
    11701 tgtatattta atttacatat atttgttaat ttttatgttt ttttaaagta aaaagtggtg
    11761 ataatatgat aagattaata ttaataagac atgcactgac aaatgataat aaaaaaggaa
    11821 gattatcagg ccatataaat agttgtatta gtgaagaggg caaactacaa ataaataaaa
    11881 ttaccagata tctgagtaat gaaaacatag ataaggttta tacaacacca tctacacgta
    11941 ctaaagatac agtagaaaaa atatcaaaat tgaaattatt agaaatagaa gaaaaagaag
    12001 ctttaagaga aattagtttt ggagactttg aaggaagaac ttttgaagaa attaaaatca
    12061 aatatccaaa tgagtttgaa aaaatgataa aagaaggtaa caactataga tatccaaatg
    12121 gagaaagttt gatagactct tataaaagag tggcaaaaga aattgataat ataattttag
    12181 aaaatgatag taatttagat acaaagacaa tacttatatg ttctcatgca ggaacaataa
    12241 gaaatataat aacacatttg atttctggta gttataagta tcactggaac tttaaaattg
    12301 ataatgcatc tattacagtt ttagaaattg atggtggatt tgctgtaata gataaaatga
    12361 attttacaga cttcatataa tttaatcaaa accaaacatt acaatctgtg tttgtaatat
    12421 atctgtaaaa ttagcaatga aaatagaata ttagattaaa attaggttct taattagatg
    12481 ttaaaaggga aaaaggttag atgcctttgc agcccccgct actgtgaaac caacgaaact
    12541 ataaatacca ctgtcagttt gatgggaagg ttatagaagt aggatgaagt taagccagga
    12601 tacctgccta atttaattta aaacaagagg tcttcggggt gaaagatttt taattaatat
    12661 atataaaagt cctatcttta gaagtattag gacttttttt aatttgtttt ttagtaaatt
    12721 ttaacaagga gggatggaaa gtggggaaaa aaataatgct acaaggaaca gcttcaaatg
    12781 taggtaaaag tgtcttagta gcaggtttgt gtagaatatt taagcaagat ggttatactg
    12841 ttgctccttt taagtcacaa aatatggctt taaattcttt tataactaaa gaaggattag
    12901 aaatgggaag agcacaagta tttcaagcag aggctgcgaa aatagagcca atagctgata
    12961 tgaatccagt tttattaaaa ccttctggaa ataataaaag tcaagttatt gtaagaggta
    13021 aagttgtagg agaaatgcct tcttctaagt atcatgatta taaattggag ttagtagatg
    13081 tgttgaagga aacatttaat agcttaaatt caaggtatga tattgtagtt atggaagggg
    13141 caggaagtaa tgcagagata aacttaaaag atagagatat ctctaatatg ggtatggcag
    13201 aaatagctga tgcacctgta ataatagtcg gagatattga tagaggaggc gtatttgcct
    13261 cattagcagg aacaatgctt ttattaaatg aagatgagaa aagaagagta aaaggtgtaa
    13321 taatcaataa attcagagga aaaaaagagc ttttacaaga tggtgtaaag atgctagaag
    13381 acatcataaa agtacctgtt ataggagtag taccttatac agatataaaa atagaagatg
    13441 aagacagtgt aactacgaga tttaagaaaa aaatgaataa aagtgatata cacatagaaa
    13501 taattagaac cccacatatg tcaaatttta cagattttaa tatatttgag acacaagaag
    13561 atgtaagtat tagatatgta gactatggag aatctttagg aaatccagat atattaataa
    13621 tacctggaac taaaagtact atagacgatt taacatatat aagaaaaagt agtcttgaat
    13681 cgcaaatcaa aaatttacat agtcaaggta aattgatatt tgggatatgt ggtggatacc
    13741 aaatgttagg taaaaaatta aaagaccctt atcatgttga aagtgaaatt gaagaagttg
    13801 atggaatagg tcttttagat acagaaacaa cgtttgagaa agaaaagact acaacacaag
    13861 tagaagctac tattgttgaa tgtatcagtg aatacatgaa taaccttaag ggaaaaaaag
    13921 taaaaggtta tgaaattcat atgggaatta caaagcgagg taatgatgta agaagtttag
    13981 atttaataac taaaaaactt gataaagaag tgaattatac tgagggaagt gtaaataaag
    14041 aggggaatgt aattgggact tatcttcatg gaatatttga tgaaataagc tttacaagag
    14101 caattttaaa caatataaga aagaaaaaag gtttaggaga attagaaagc aaagtaaact
    14161 cttttaatga atttaaggat aaagagtatg ataagttggc tgatttttta agagaacatt
    14221 tagatataga gaaaatatat gagattatga aataatgatg acctttattt ataatttaag
    14281 taggaggtgt attatgaaaa aaattttaat tgcgggtact aatagtggag taggtaaaac
    14341 aacaatatca ttaggaataa tgcaagcttt ggttaagaga aatatgaaag tacagccata
    14401 taaagtaggg ccagactata tagacccttc atatcacact tttataactg gaagacattc
    14461 tagaaattta gattcttata tgttagatga tgaaaaaata aagtatatag taaataagtc
    14521 ctcaaaagat gcagatattt cagtaataga aggtgttatg ggcttatatg atggctttgg
    14581 aatagattta gataattgta caagttcaca tacttcaaag gtattaaagt cacctgttat
    14641 attagttata aatggtaaat ctatggcagc atctagtgct gctatggtac ttggatataa
    14701 ggaactagat aaagatgtaa atataaaggg tgttatagta aataatgtaa agactaatag
    14761 ccattatcaa ataattaaga gttctataga aaaatattgt aatgttgaag tattggggta
    14821 ttttcctcca aataacaaat tctctttgga atctcgacat ctaggattag ttcctagtgt
    14881 agaaatgaaa tcactaaggg aaaaatttta taccttagca gatgaaattg aacactatat
    14941 agatattgac agaataattg aaatatcaga aagcgatgaa tttgagagtg attttgattt
    15001 tcaaacttta atagaaaata ataaaataaa agaacatgtt aataataaat caatagctat
    15061 agcatatgat aaagcattca atttttatta tagagaaaat atagagcttt tagaggaact
    15121 tggtttagaa ataaactatt ttagccctct tgaagatgta tcagtgccaa atgcagatta
    15181 tatttatatt ggaggaggtt ttccagaaat atttggaaaa gaattagaag caaatgagtc
    15241 aatgagaact tccatattag aagcacataa caataatata cctatttatg cagaatgtgg
    15301 aggactgatg tacctaggtg agaaactatt gaatcaagaa gaacaagaat ttaatatggt
    15361 tggaatattt agtggaatta gtaagatgac atcttcttta aagagatttg ggtactgtat
    15421 tggtgtagcc aaggaaaata ctcttttatc taaaaaaggg gaatctatta aagggcatga
    15481 gtttcatcat tcaatatttg aaagtgatga aaaatgtgta tattcaatga gaaaagaaag
    15541 agatggaaat atagtagaag agtgggatgg tggttatagt aaaggaaaca ctttggctac
    15601 atatcttcat actcattttt ataataactt aaattgtata gaaaattttt tgaaaaaagg
    15661 aaatgaataa atgagtattt tatctattta tataggatat gtgacagact taattgtagg
    15721 agacccatat tcttttcctc atccagtgag atttattggt aaacttataa attttactca
    15781 aggtataata agaaaggtct ctaaaaatga taggcagtta aaatttgggg gatttatatt
    15841 atggtttata accgttggaa taacatattt aacaacttat gttatagtga agttatttag
    15901 ttttaatata ttattgagta ttgtagtgaa tagttttata atttatacaa cattagccac
    15961 aaaatgttta aaagacgaag cattaaaaat ttataatgta ttaaaaactg aagatataga
    16021 aaaatctagg attcagctat cttatatagt aggtagggat actactaatt taagtgaacc
    16081 tgaaataata agagcaactg tagaaactgt tgcagaaaat actgtagatg gtataattgc
    16141 gcctatgttt tatgcattta ttggaggagc accacttgct atggcctata aagctatcaa
    16201 tacattggac tcaacagttg gatataaaaa taaaaagtat aaagatattg gttttgcatc
    16261 tgctaagatt gatgatatag ccaattatat accagctaga atatctgtca ttcttatgac
    16321 aattggaagt ttctttttaa attataacta taggaactgt tttaaaatct ctattagaga
    16381 tagaaagaat cataaaagtc caaattgtgc tttttcagaa ggtgcagtat ctggtgctct
    16441 aggaatacaa ctaggaggta ccaacgttta ttttggggaa aaagtatata agccaacaat
    16501 aggggataag cttagggaga tagataaaga agatataatt aaaactaata aaattatgta
    16561 tgcatcttca tttgtatcta tgttggtatt tacactaata tatgtgttat gtaggatgat
    16621 tttaattaac ttaattatat aaattattgt ttgttaactt aagggggaca tagatgaagg
    16681 atttagggca tggtgccaat gtagatgaaa tggcaagatt atatgggaaa aacccaaaag
    16741 aaataattga ttttagttca aacataaatc caaatgtatt accaaattta gagagataca
    16801 ttttaaaagg attagaagag tgtaggaatt atccagatat aaattataca aacttgagag
    16861 aaaatatatc aaaatatata gatataaatc cagactttat aatacctggc aatggtgcaa
    16921 cagaagtgat ttatttgctt atgaagagta ttaaaaaaaa attggctata ataaatccga
    16981 ctttttcaga gtatagaaga agtgctgagt taaataattt agatattata gatttagagt
    17041 tagatttaga aaataacttt aaacttaata tagatataat aaaagaaaat ataaaaagat
    17101 ttgatagttt atttatatgt aatcctaata atccgagtgg taatgtccaa gatttaaagg
    17161 aacttgttca tttactagat aaacataata aggtactaat aattgatgaa actttcatgg
    17221 aatttgttga agatgaaagt aaatatagtt tggttaaata tatagaatca aataaaaata
    17281 tatttataat taaagctgtg actaagtttt ttggtatgcc tggtttaagg ctaggatatg
    17341 gtcttacaag caacactgaa attatgaaca aaatttatga acacaaagag ccatggacta
    17401 tcaattcttt tgcagatata ctatccaatt ttatttttga agataaagag tatattaaaa
    17461 atagtaaaga atattacata gaagaaagaa aatatatgtt acaagagttg agaaacataa
    17521 gaaatataaa ggtctatgat acagatgcta attttatctt gataagaata tataaaaaaa
    17581 caactaaaga attgaaaaaa gatttgttta agcaaggaaa catattagtt agagatgcat
    17641 ctaattttat aggattagat gatagtttta taagagtggc tataaaatct catgaagata
    17701 acaaaattct tatagaaaat atgaaaaatt tattgggtga ttaaaatgaa atcttatgga
    17761 atatgcccag catcttgtgg agaatttgta caaggtataa ttgatgatga agaatattta
    17821 tgttcatatg caatagatat gtattctaaa gtgtatattg aagaaaaatt agtagatata
    17881 aatttaggga gatataagtc aaggttagca attgaaaagg tatttgaaaa atttaattta
    17941 cctaaaaaat atactaaaaa tatttcttta aatataaata gtaaaatacc tgttggaaaa
    18001 ggaatggcaa gttcaactgc tgatatagga gctactataa aggcaacatt atcattgata
    18061 gataaagatt taagtagcga ggagatttct aaattagcag cagaaataga accaacagat
    18121 tctatattta tagataaaaa tagtatattt aatcctctaa atggaactgt tataaaatac
    18181 ctaggaaatc tgaccaatgc gaaagttgta atacttgaac caaacaaagt actagatact
    18241 atgaagatta gattgaggca agattataat aaattaaaag tagagaataa agaagtaata
    18301 aaaaaatcat ttgctctttt agaagaagga ttgaaaaaaa ataatttatc tctagttgga
    18361 gaggcttgta ctttgagtag cttagcaaat gagaatatag aaaaaaaaga gtgtttaaat
    18421 gaaataataa aaatatcaaa aaaatatgga gcatatggag taaatattgc tcacagtgga
    18481 actgtagtag gtattttaat tgataagtct atgaatgata aaaagatgat agatgcctta
    18541 tgtgaatcta acataaattc tgtctataat aaaatttata cacaaaacat aattaatgga
    18601 ggaattaagg gggaaataga atggaataca taaagaatcc tatgaaaata gaagaaaaaa
    18661 gttttgaatt gatacaagaa ataatagacg aaattagacc agattataaa tttaagaata
    18721 atatcgaaga aaaaataata aaaagagcta tacatactac tgctgatttt gattacttag
    18781 atatattaaa aatatcagaa gaagcagttg atagtataat agatgcatta aaaaataatg
    18841 caagtattta tactgataca aatatggctc ttagtggtat aaataaaaga aagttagaat
    18901 cattaggatg taagtataaa tgtttagtgg cagatgatga aactgtaaaa ttagctaaag
    18961 aaaaaggaat tactcgttct atggcagcag tagaaattgc agctaaagaa gaaggaagaa
    19021 aaatattcgt tttaggtaat gctccaacag ctttatataa agttatggag atgaaatcag
    19081 aaggtagatt agatttagat gcagttatag gagttcctgt aggttttgta ggagcacaag
    19141 aatcaaaaga tgaagttgaa aaaacagata taccatatat aatttctaaa ggtagaaaag
    19201 gtggcagtaa tttagcagca gcaatagtaa atgctatatt atatactatg taggtaccta
    19261 tatggaagaa tatgtatata tagatggaaa aaaatataga agaggatata ctacaggttc
    19321 atgtgcaaca ggtgcatcta aggctgctgt atatatgttg attacaaaaa atagaatcaa
    19381 tactataaat atagatactc ctaaggggat accattacta ctaaaagttg ataatataaa
    19441 tatttctgat acatttgtgg aatgttccat aaaaaaagat ggtggagatg atatagatgc
    19501 aactcatacc atggatattt atgcaagagc tgaaattgta gctaaaaatg ataagaacaa
    19561 agggtatctt actctaaagg atatagatag tttaagcacc aatagtgagt gtaaaagtga
    19621 gctctataag tttattaggg tttatggcgg aactggtatt ggtgtggtta cgaaaaaagg
    19681 gcttagtgtg gatgttggta agcctgctat aaatccgact ccacttaaaa tgataaatca
    19741 tgaaataaga aagcttatag gagataattt tgaatctata cttggaaatg ataaagtttt
    19801 aaaaataaca atctttgctc cacaaggaga aactgtagca aaaaaaacat ttaatccaag
    19861 attaggtata gttggaggaa tatctataat aggtacaact gggattgttg aacctatgag
    19921 tgatgagggt tggaagaagt ctctatctat agaacttcag atgaaaaaag aacaaggctt
    19981 agataaaata atattggttc caggaaatca tggagaacag tttataagag aaaaattaaa
    20041 cttagatatt aagtatgtag ttagggtaag taattttata ggctatatga ttaaagaagc
    20101 tcaaagaata ggatataaga aaatcttaat ggcaggtcat ataggtaaat ttataaaagt
    20161 atctgctggt atttttaata ctcatagtaa ggtagcagat gctagaagtg agatattagt
    20221 ggcaaactta gctttaatgg gagctagata cgaattttta aataaaataa atcaatgcgt
    20281 aactactgaa gaagctgtag agctaataaa taatagtgaa tatagagaag tatataatat
    20341 attaagtaat aaatgtaggg agagagtaaa gcaatacttg aatgaagatt cagatgatat
    20401 tgatgtggaa gtaatcatat tttcaatgga taagtcttta ttaggtaaat cggataatac
    20461 agatgattta gtggaggtct ttatatgata aacataatag gtctaggacc tggcaactta
    20521 gactatataa caaaaaaagg tgaaaattta atttccactt ctgatgtatt aattggtggt
    20581 aaaagaaatt tagagtctat aaaaaatttt gaaggagaaa aaatagttct ggattctaat
    20641 ttaagagaaa ttatagagta cataaataac aataaagaaa agcaaatatc aataatagca
    20701 tctggggacc cattaatata tgggataggt agatatctat ctaaaaatat tgataataag
    20761 atgttaaaca tggtttctgg gattagttca ttacagtaca tattttcaaa aatatatgta
    20821 gatatgaatg atgtatatat tacaagtagt catggcaaag taccagattt tgattacata
    20881 ttatcacata aaaaagtatg tatggttaca gattcaaaga taggaccaaa acaaataagt
    20941 agagaaataa tagatagaaa tctaaataaa attattgttg taggagaaaa tctgtcatat
    21001 gacaatgaaa aaataacaat agcaaaacca gaagagataa taagaataga caattttgat
    21061 atgaatgttg tggtgatttt agatgaggaa tagtgagttt ataacaggta aagttccaat
    21121 tactaaggaa gaggttagag caatatcaat aagtaagtta aatttagtaa atgctaaaaa
    21181 cctcatagac ataggggctg gtacaggaag tgtaagtgtt gaagctgcat ataattatcc
    21241 taatttaaag gttatatcta tagagaaaaa tgatgatgct atagagctta tagagaaaaa
    21301 taaaaaaaaa ttcaacttaa aaaatataga agtgataaaa ggatatgctc caattaatct
    21361 agggttaaat gttaaagttg agtctatttt tcttggggga acaggaaata atctggaaga
    21421 aataatagaa tggtctaaaa aaaatctcgt tacaggagga agacttgtag ctaattttat
    21481 aataatagat acatttaatc aaactttaaa actgcttaaa aagcatggat ttaaagaaat
    21541 agatgtatgt gttttgaatg tttctaaact agagaaacta ggaaaaggtg aatattttaa
    21601 accactaaat cctatatata taatatcttg tgaaaaaggg gaaaatgatg atgaataaag
    21661 tacattttgt aggagcagga cctggagata aagagctgat aacattaaaa ggatacaaat
    21721 tattaagtaa tgcagatgta gtgatatatg caggttcact tgttaatcct gaacttttgg
    21781 aatactgtaa agaagattgc caaatacata atagtgcaca tatggattta caagagataa
    21841 tagatgttat gagagaaggt atagaaaata ataaatctgt tgtaagactg caaacaggtg
    21901 atttttctat atatggttca attagagaac aagtggaaga tttaaataaa ttgaatatag
    21961 attatgactg tactccagga gtaagttctt ttttaggagc agcatcatct ttaggggttg
    22021 aatatacagt tccagaaatt tctcaaagtg taattataac aagaatggaa ggcagaactc
    22081 cggttccaga gaaagaatca atacaatcat atgctaagca tcagacatct atggtaatat
    22141 ttttatctgt tcaagaaatt gagaaagttg tgtctaaatt actggaaggt ggatatccaa
    22201 aagatactcc tatagcagtt atatacaaag caacttgggc agatgaaaaa atagttaaag
    22261 gaactttaag tgatatagct gtaaaagtta aagaaaacaa cataaataag actgctttaa
    22321 taatggttgg gagattttta ggagaagagt ataataattc aaagttatat gataaggatt
    22381 tcaaacatga atatagaggg taatattgct ataatctgta ttacagaaaa tggaaaaaaa
    22441 ttagctctaa agataaattc tctagtaaat aactgtgtta tatatcaagt aaaaaataaa
    22501 aaaagtaatt tagttgttga agaaacatgt gtacatacag ttcaaaagaa gttaagtgat
    22561 tttgtaggag aaatatttag caaatttgat tacatagtat ttataatggc tacaggtata
    22621 gttgtacgaa gtatagcacc atacataata agtaagttta gtgaccctgc aattttggta
    22681 atggatgaaa aaggcaaaaa cgtaataagt ttattgagtg gtcatattgg aggggcaaac
    22741 agcttgacac agtacataag tagtcttatt gatgctaatc cagtaataac aacagctact
    22801 gatataaatc aaaaagcttc cttagatatg atagcaaaaa aactaaatgc acatattgat
    22861 aattttagag aaagtgtaaa agaagtaaat tctatgctag tgaataataa atgtgttgga
    22921 ttatatattg atgaaggata tcaagttgat actaggggat ttaaacttat agaaagtaag
    22981 gatgagttaa gagatagttt ttcaaacaca tatatagaaa aattagttgt agtaagcaat
    23041 aaaataaatt gtattgaaga tattgagaat ttaaacctag ataataaatt tgaacattgc
    23101 tatagtacca aaaaaataat aaaggtaatt ccaagagata tagtgatagg aattggctgt
    23161 agaagaaaca cagatagtga gctgatgtat aattcacttg aagagtttct taataaacaa
    23221 aatatagata ttagagcaat aaacacagtt ggaagtatag aactgaaaaa agacgaaaaa
    23281 gcaataattg aattatcaaa aatattgaag gtgccattta aaacattttc agtagatgaa
    23341 atatctaagg ttgataatct ttttgataaa tctgattttg ttaaaaaaaa tgtgggcgtg
    23401 tattcagtag cagaacctgt agcatatctt ttgagcaaag gtaatttgtt agttgaaaaa
    23461 cataaatata aaggaataac tttttcagtg gggagaataa aaatatgata tacgttgtag
    23521 gaattggacc aggaagtaaa gatacaatga ctttagaagc aataaaagca atagaagatt
    23581 ctgaggctat tgttggatat aagacttata taaaactaat agaagaattt atacaagata
    23641 aagaaataat ccaaaatggt atgaggcaag aagttgatag atgtaaacaa gcagtagagg
    23701 aagcaaaaaa aggaaaaaaa gtagcagttg taagtagtgg tgatgctgga atatatggga
    23761 tggcaggtct tattttagaa ttaatatcta aagaagatga agatataaaa gtaaaggtaa
    23821 ttccaggtgt tactgcaagt attggtgcag cagctatact tggagctcct attatgcatg
    23881 atttctgtca tataagtttg agtgatttaa tgactccgtg ggaagtaatt gaaaaaagat
    23941 tgagattggc tgctgaagcc gattttgtaa tttgtttgta taatccaaga agtaagggaa
    24001 gaagtgaaca tctaagcaaa gcatttaaaa taatgggtga gtttaaaagt ggagatacac
    24061 ctgttggagt ggtaaaagat gtaggtagag aaaaagaaga aaagcttgta tgtacttttg
    24121 aaaatatgga ctttgaaaaa gtcgatatga ctacaatggt tataatagga aataagtcta
    24181 cctatattaa tggtgaattg atgataactc caagaggtta tacagtatga ttttaatttt
    24241 aggaggaact tcagatagtt tatctatatg tgataagata aatgaactga aaaatcaacc
    24301 atatatcctt tcagttacta cagattatgg aagggaactt gcacaacaac atgcagagaa
    24361 tgtaatttta ggtaagcttg gaaaagaaga tatgctaaaa tttataaaag ataataatat
    24421 agtaaaaata atagatgcca ctcatcctta tgcagttgaa gtatccaaaa ctgctattac
    24481 ttgtgcaaaa ctattgaata tagattatat aaggtttgag agaaaatctt taattgaaga
    24541 aatagattat gataataaat ttatagtaga tacaattgaa gaagcctgtg aaatagcaaa
    24601 taaaataggg acaaatatat tcataggaac aggaagtaaa aatttgaaca gatttataga
    24661 ggaaataagt gataaaaatt tagttgttag agttcttcca acgagtgaag tcatattaag
    24721 ttgtgaaaaa ttaggtttaa gtgcagataa tatagtagct atgaaaggtc catttagcca
    24781 gtatataaat gaagaaacat ataaacatta caatatagat ttagtcataa caaaagaaag
    24841 tggaatagct ggtgggttct tagagaaggt aaatgcatgt aaaactttca atataccagt
    24901 aataattata aaaagagaat cgattaacta cgaaaatgta tttaatgaca taaataaaat
    24961 taaagacata cttgtgtaat ttttaggagg agaatatatg aagaaagcct tattagtagt
    25021 gagttttggt acaagctatc atgaaacgag agaaaagaca atagatatat gtgaagataa
    25081 aataaaaaat tcgttaaaaa gccatgattt ttttagagct tatacatcaa atatgataat
    25141 aaataaaata aaaaaaaggg atggaataga aatagataat ccaatacagg ctttagataa
    25201 aatatatgaa caaggatatg atgaagtaat aatccaaaca cttcatatta tatgtggcga
    25261 agaatttaac aaattaaaag aacaagtaga tggatattct tctaaattca aaaagattgt
    25321 attaggaaga cctttgctta cacatattga agattatcag gaagctgtag aggcaattaa
    25381 gcatcaaatt cctcatatgg aaagtaatga agcagtagta tttatgggac atggaacact
    25441 tcatgaatca cattcagcgt atccagcatt ggaatacatg cttagggata atggaataaa
    25501 tgcttatgtt ggtacagttg aagggtatcc agaaatagaa catgtaataa gaagattaaa
    25561 agaaggaaat ataaaaactg taaatttgat gccatttatg ttagttgcag gagaccatgc
    25621 tataaatgat atggcaggag atgaagaaga ttcttggaaa acaatattag aagaaaatgg
    25681 atttaacgta agagttcatt taaaaggact aggagaaaat tcttatatac aagataaatt
    25741 tgttcgtcat gctgtaaaat gtgcagagaa tgcgaagttc tatggtatag gagcaggacc
    25801 aggagatggt tctttactta cgataaaagc ggttaatact ttaaagaaac tggatattct
    25861 atacactcca gaatcaaaaa agggtggaga tagtctagct ttatcaatag ttagtgaata
    25921 tttacctgaa tcagtggaaa taaagtctag gcatttccca atgagttttg atgggaatga
    25981 aaaaagttta gcttgggata atgtggcaca agaaattata tcagatgtta atgatggtaa
    26041 aaatgtagga tttgttacat taggagaccc tatgatttat agtacatatg tatatataat
    26101 gaaaagaata ttaggagagg tagaagtcga aactatacca ggaatttcat cattttccaa
    26161 tatagcatct aatcagaatt ttccattagt catggataaa gaagctttag tggtaattcc
    26221 ttgtactatg gaagatgata agatagagta tgctttgcaa aattataatt caatagtatt
    26281 gatgaaagta tataaaaatt ttaaagaaat aataaaaaaa ttagaaaagt atgatttaat
    26341 agaacatgct attttagtaa gtaattcttc ccaagaaagc gaaaatgtgt ttacagattt
    26401 aaaagaagcg caccttgaag ataagatatc ttatttttct actatactag taaataaaga
    26461 taataaaata aaataggtga aagcaatatt taaaggagac ttaatatgaa tatagtggtt
    26521 ggaactaggg gtagtaatct agcgcttata caaacagaat gggtaataaa tgaattaaaa
    26581 aagaagtatc cagaaattag ttttgagatt aaaatcataa agacaaaagg agatttaatt
    26641 caaaatgttt cactggataa aataggtgat aaaggattgt ttgtcaaaga aatagagcaa
    26701 caattattag atggaaaaat agacatagca gtacatagta tgaaagatat gccttcttat
    26761 ttagcagatg gactaaaatt tgctcatacg cctaagagag aagacccaag agatgttcta
    26821 atacttagag aaggatataa aaatttagat gatttacctc atggagcagt aataggaaca
    26881 ggaagtaaaa gaaggaagtt tcaattattg aaacaaagac ctgatttaaa tatagtacaa
    26941 gttagaggta atgtggaaac taggatacga aaaataaaag atgaaaatat gcatggtatt
    27001 gtgttggcag catcaggaat aattagagct aatttgcaag ataaaataag ttcttattta
    27061 cctgttgatg ttgttattcc agcacctgcc caaggagctt tagctataga aattagaagc
    27121 aatgatagta cgatagaggg aatagtaaat tcactgaagg atgagaatac agaaatccaa
    27181 atattggctg aaagaggttt tttagatggt gtaaatggaa gttgtcatat tccaatggca
    27241 gcttattgtg aaataatcca agataaaata catcttactg gcttatatgg agattcagaa
    27301 ggaaaaaaag tagtaatcaa gtctatagat ggagatattt cttctcctag agagttaggt
    27361 ttaaagttag ctaaacttgt attgaaggag tatgagaatt atgaagggta aggtttactt
    27421 agtaggggca ggaccaggtg attataaact catgacttta aaaggtttag agtgtataag
    27481 aaaatcggat gtaatagtat atgatagatt agcaaatagt agttatttaa gagaagctaa
    27541 gcctgattgt gaacttatat atgtaggcaa ggcatcaagt aatcatattt tgccacaaga
    27601 agatataaat agaattatag cagaaaaagc taaagaagga aaaattgtaa ctcgtcttaa
    27661 aggaggagac ccttatgtat ttggcagagg gggagaagaa gcagagactt tagtagatga
    27721 aggtatagaa tttgaagtgg ttccaggtat aacttctgct ataggaggtt tatgttatgc
    27781 gggtattcct ataacacata gagaccatgc ttcgtcattt catgtaataa caggtcattt
    27841 gaagggtgat gatagtggag aattaaactg gaatgctctt gcaaataaca aaggtactct
    27901 tgtgtttttg atgggaattt caaacctaga gaaaataagt gaaaacttaa tgaaagaagg
    27961 aaaagataag gatacacctg ttgctcttat aagttgggca actagatata atcaaagagt
    28021 tgttacatct acacttgaaa atgtttatga aactgctatt aaagaagaag taaaaccgcc
    28081 aactcttata gtagttggga gtgttgtagg acttagagaa aagttgaact tctttgaaag
    28141 taagccttta tttggaaaaa gtattgctgt aactaggtct agaaatcaaa atagtgtatt
    28201 ggtagaaaaa ataatggatt taggtggaaa tcctatagaa atacctacta ttaaggtaga
    28261 aaaaatacaa aataatatta acttagaaaa tgaaataaaa aatataaata agtataatta
    28321 tctaatacta actagtaaaa atgccgtaga aatcttcttt gaaaagatat atgaaatgaa
    28381 ttttgattta aggatattat ctaatttaaa ggtatgtgct ataggttctg ctacatcaaa
    28441 tgagttgaaa aaaagaggaa ttatagcgga tatagtacca aaaaaatttg tagcagagtc
    28501 actgtatgaa gagttagcgc ctattttaaa tgatgacgat aatatactta tacctagagc
    28561 agaaaatgct agagattatc tggttgacaa acttaaggct atttgtgaag taacagaagt
    28621 acatatatat agaacagtaa tagatgagga gaaaaaaggt gagatattag atattttaaa
    28681 ttctaatgac atagattata taacatttac tagttcctca acagtaaata atcttgttga
    28741 aattatagga aaagaaaata ttaaaatatt agaaaaaata aaaacactat ctataggtcc
    28801 tataactaca gagacaataa atagtttggg aataaaattg tacaaagaat ctgctacatc
    28861 tactatagat tcgttagtag atttaattat aaaaaattaa ttttggaggc ttgaatatgt
    28921 taagaagacc aagaagacta agagcaagta aagcaatcag aaatttggta agagaaacta
    28981 aggtgaatgt agaagactta atatatccac tgtttgtagt agagggggaa aatataaaag
    29041 aagaaattaa atctttacca gatgtctatc atttatcaat agatatgcta gaagacgaaa
    29101 taaaagaaat aagtgagttg ggaattgaac atataatgtt atttggtgtt ccagatgaaa
    29161 aagatgagtg tgcttcacaa gcttttaatg ataatggaat agttcaaaag gcaattagaa
    29221 aggtaaaaga aataaattca gatataaatg taataacaga tgtctgtatg tgccaatata
    29281 caagtcatgg acattgtggg attttaactg atactggtta tgttgataat gataaatcat
    29341 tggagtattt ggctaaaata tctgtaagcc atgctaaagc aggagctgat atggttgctc
    29401 catctgatat gatggatgga agaatacaag caataagaga agctttagat gaaaatggat
    29461 tagaaaatgt tggaatcatg gcttatagtg ttaagtatgc ttcaaattat tatggacctt
    29521 ttagagaggc agctcattca gcaccatctt ttggagatag aaaaacatat caaatggacc
    29581 cagcaaatag caatgaagct ataatagaga ctgaacttga tatattggaa ggtgcagata
    29641 tacttatggt taaacctgca ttatcatatt tagatattat aagaagagtt aaagataatt
    29701 ttgacttacc tctagcagct tataatgtaa gtggagaata ctctatgctt aagtttgctg
    29761 tgaaggaagg tttattaaat gaagatgtaa ttcttgaatc aattacatct ataaaaagag
    29821 caggagcaga tataataata acttattttg ctaaagacat tgctaaactg ttgaaaaaat
    29881 aaattctagt agtataaaga atatcaaaaa gtataggaat tgtaattaac tattatacag
    29941 tagttttgtt tagacattta ttgaagaata atagaaacta atttgcaatt tctatacttt
    30001 atttatgtaa ctaaataaaa tttggaggta gaagatgcta tatcctatta atttaaaatt
    30061 agatgagtta gatgtagtta taattggtgg tggagaagtt gcatatagga aatgtaaaaa
    30121 ttttttagag tttaacaaaa atgttactat agtttctaaa caaattttaa ataaatttta
    30181 tgatttaaaa ggaaatataa aaataataaa agatgattat aaagaaatat atataaaaga
    30241 tgcttctgta ataattgctg ccacaaataa tagagagtta aatatggaaa taggattata
    30301 ttgtaaagca aaaaataagc tagtgaatgt agttgataat atagaaatat cgaactttac
    30361 tgttccatca tatataaaaa gaggagattt acttataagt gtgtctactg ggggcaagag
    30421 tccttcatta tcatcaaaga taaaaaaaga aattgaagag agatatactg aagattatga
    30481 ggagtattta aatgtattag gagatataag aaaaaaggtt ataaaaaaat acgaagataa
    30541 aagtaaaaga aaagatgtgc ttaatatgtt ggtaacactt gacctagaag aacttaagaa
    30601 gtttgatata taaaaaataa aataaaaaat gttaaaaagg tgttgacgga ttatttttaa
    30661 gatgatatag tattacttgt ccttaagaaa agggcaaaca taaaaaa
//
LOCUS       DAEOTL010000043        29689 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEOTL010000043 DAEOTL010000000
VERSION     DAEOTL010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.043"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(50..1126)
                     /locus_tag="KRH82_002311"
     CDS             complement(50..1126)
                     /locus_tag="KRH82_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBG8655585.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(1499..2014)
                     /locus_tag="KRH82_002312"
     CDS             complement(1499..2014)
                     /locus_tag="KRH82_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBG8655586.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(2377..3447)
                     /gene="leuB"
                     /locus_tag="KRH82_002313"
     CDS             complement(2377..3447)
                     /gene="leuB"
                     /locus_tag="KRH82_002313"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBG8655587.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEELAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTRAMGELIVNEI"
     gene            complement(3454..3945)
                     /gene="leuD"
                     /locus_tag="KRH82_002314"
     CDS             complement(3454..3945)
                     /gene="leuD"
                     /locus_tag="KRH82_002314"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBG8655588.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(3960..5237)
                     /gene="leuC"
                     /locus_tag="KRH82_002315"
     CDS             complement(3960..5237)
                     /gene="leuC"
                     /locus_tag="KRH82_002315"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBG8655589.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAKLKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(5194..6936)
                     /gene="leuA"
                     /locus_tag="KRH82_002316"
     CDS             complement(5194..6936)
                     /gene="leuA"
                     /locus_tag="KRH82_002316"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBG8655590.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(7060..7306)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7454..7900)
                     /locus_tag="KRH82_002317"
     CDS             complement(7454..7900)
                     /locus_tag="KRH82_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655591.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(7921..8640)
                     /locus_tag="KRH82_002318"
     CDS             complement(7921..8640)
                     /locus_tag="KRH82_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBG8655592.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLQHLDYIIASL
                     HRPCIASGTKEENTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(8758..10032)
                     /locus_tag="KRH82_002319"
     CDS             complement(8758..10032)
                     /locus_tag="KRH82_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBG8655593.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(10232..11599)
                     /locus_tag="KRH82_002320"
     CDS             complement(10232..11599)
                     /locus_tag="KRH82_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8655594.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(11849..12313)
                     /locus_tag="KRH82_002321"
     CDS             complement(11849..12313)
                     /locus_tag="KRH82_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBG8655595.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(12318..12947)
                     /locus_tag="KRH82_002322"
     CDS             complement(12318..12947)
                     /locus_tag="KRH82_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBG8655596.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKVKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(12981..13868)
                     /locus_tag="KRH82_002323"
     CDS             complement(12981..13868)
                     /locus_tag="KRH82_002323"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBG8655597.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(13897..15135)
                     /locus_tag="KRH82_002324"
     CDS             complement(13897..15135)
                     /locus_tag="KRH82_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655598.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            complement(15519..16661)
                     /locus_tag="KRH82_002325"
     CDS             complement(15519..16661)
                     /locus_tag="KRH82_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBG8655599.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(16802..17668)
                     /locus_tag="KRH82_002326"
     CDS             complement(16802..17668)
                     /locus_tag="KRH82_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBG8655600.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(18002..19549)
                     /locus_tag="KRH82_002327"
     CDS             complement(18002..19549)
                     /locus_tag="KRH82_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBG8655601.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMRHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(19542..20678)
                     /locus_tag="KRH82_002328"
     CDS             complement(19542..20678)
                     /locus_tag="KRH82_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655602.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLAVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(20941..22038)
                     /gene="dinB"
                     /locus_tag="KRH82_002329"
     CDS             complement(20941..22038)
                     /gene="dinB"
                     /locus_tag="KRH82_002329"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBG8655603.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(22428..23933)
                     /locus_tag="KRH82_002330"
     CDS             complement(22428..23933)
                     /locus_tag="KRH82_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBG8655604.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(24196..24546)
                     /locus_tag="KRH82_002331"
     CDS             complement(24196..24546)
                     /locus_tag="KRH82_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655605.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(24769..24960)
                     /locus_tag="KRH82_002332"
     CDS             complement(24769..24960)
                     /locus_tag="KRH82_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655606.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(25078..26004)
                     /locus_tag="KRH82_002333"
     CDS             complement(25078..26004)
                     /locus_tag="KRH82_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8655607.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            complement(26138..27634)
                     /locus_tag="KRH82_002334"
     CDS             complement(26138..27634)
                     /locus_tag="KRH82_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8655608.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(27914..29404)
                     /locus_tag="KRH82_002335"
     CDS             complement(27914..29404)
                     /locus_tag="KRH82_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8655609.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
BASE COUNT         9630 a         5393 c         3083 g        11583 t
ORIGIN      
        1 tttattatat attctaaatt tatcttaaaa catacatatt tttacaatat tatttattaa
       61 aacctaatat atcatcaata ttatctaata attcttgtac atcttcgaca gtatagtcac
      121 ccatatgtga aattctaaaa gttttttctt ttaaatctcc atagccattt gctatttgga
      181 atcctcgttc ttgtaatttt gaatttaaat ttgatacact aataccttga gtattttcta
      241 taacagtaag tgtattggat aagtgatttt cattggtaaa aatttggaag tgttttttag
      301 cccagtttct aactaagttt gccatgtctt catgtctgtt gaatctgtta tctaggcctt
      361 catctaatat attatctaat tggaaatcta aagcgaacat gtgagaaaga gatggtgttg
      421 aagggtattg gtagtttttc ttgattaagt attcatacat tgctaacaaa tcaagatata
      481 ctcctctaaa aggtacttgc ttagctctat cgattgcttt ttgagaaaat gtgcaaatag
      541 acattcctgg tggtaatccc agtgcttttt gtactgatgt tatacaaata tctattccaa
      601 tcttatcaac ctcgactttt attccaccgg ctgaacttac agtatctaca cagtagatta
      661 catcttcata ctttttaaca acttctccaa tttcttctat tggatttctt attccagttg
      721 aagtttcatt gtgagttaca gttattaaat cgtattctcc ggtagaaagc accttatcaa
      781 ccatttctgg cgttgttgcc tctcctaatt caactttaaa tatatccgct gggacattat
      841 tagccactgc cattttgtac catctatcac caaaggatcc acaggaaaat actgctgcct
      901 ttttggatgt acaggaacga atggagcctt ccattaaacc agttccggat gacgtggata
      961 aaagtatcgt gttgtttgta tagaatagtt tttgcatctt ttcacttata ctcttttgga
     1021 gcatagatgc atcttttcct ctatgtccta tcattggtgt agccatcttt tgcaagactt
     1081 cttctttaac atcaatagga ccaggaataa ataatttctt actcattata attcccccct
     1141 ttttagtttg taatatggat agcgttttta ctgtccttat ttttaataac tataatatca
     1201 agctgaatta actatgtcaa cataaaattt attttttata tataatttat tttatatatt
     1261 ttatgaaaac attcattttc taccttttca taagtctgaa ttttctgaat tattctctca
     1321 aaaaaaatat actttttatc tatataaatt aattttttta gtatgtaaat ttgacgctat
     1381 tacgataaat ctttttagta taactaattt atttttatct tgtattttta ttgtattttt
     1441 aaattttatt ttttctaaat ataaaattta tgttttaaaa tgtaaaattt ttatttaatc
     1501 aaagttcaat atattccact ttttctttcg attcttcaaa aaaccattct tcattagaaa
     1561 aatcaccttc tgcaatttgt ccaataggca ttttcatata ctttccagtt gctgtcactg
     1621 ctatatctcc atttggtaga attatttctc ctgtaccttc aaataatttt ctgttttctt
     1681 tagttattct tccaacaact tttatagtag catctgttgg tactggtttc ttatatttca
     1741 actctaaaga tactgttact ccccatattt ggtcatcatt tatacttaca gctcttccaa
     1801 tagtctcatc caatattgca gcagacatac ctccatgaac tctcccagga taactttgat
     1861 gccaatcctt tgtattacaa attgatacaa gctctccatt ttcaagttca taaaaatctg
     1921 ctttaagtcc tagctcattt tgtgttccac aaactaaaca agatttacta ctattttgct
     1981 tcttcaaaac tttatacttt gccaaaaaat ccatctccta accgacatta gtagtcgctt
     2041 aatattaaat aattctaaaa tatattatat aatattaata aaatccctgc aaacttctaa
     2101 taataaaaat aggctacttc aatatgataa gtttaattta aagtattatt ttccaaaaaa
     2161 taactttatc aaaatagaaa ctcaaagtag atataagcct ctttttcgtt attaaaatag
     2221 taaaaatata ttttacttaa tataaaaaag agtgtctcat taactaataa agtttatttt
     2281 gagacacccc tcataaaaca aattatacta caatagattt ttactaattc tacaagttat
     2341 atattcaaat tatattattc aaattaaact ataattctaa atttcattta ctattaattc
     2401 gcccattgct cttgttccta caacatttcc cacaccatta tagatatcaa tagttctata
     2461 acctttattg agtacacttt gtacagcatc ttcaatacac ttagcttctt cttctaagtt
     2521 aaaactatgt cttaacatca tgcttacaga tagaatagtc gcaattggat ttacaatatc
     2581 ttttccagct atatcaggtg cacttccatg tattggttca tacataccaa aactatcttc
     2641 tctaagtgat gctgatggta acatacctat agaacccgta atcatagatg cttcatcaga
     2701 tattatatct ccaaatatat tattagtcac tattacatca aattggctag ggtcttttac
     2761 aacttgcata gcagcattat caacatacat atgtgacagt tctacatctt caaactcttt
     2821 agctaattct tccattatac ttctccaaag tcttgaactc tcaagcacat ttgccttatc
     2881 tacacttata agttttttat ttctatttct ggctatttca aaagctctct taccaattct
     2941 tcttatttca ttttcgttat atatttctac atcataagca ttttcgatac catcaatgat
     3001 ttttcttcca cgttctccaa aataaatgcc ccctgttaat tcccttacaa caacaaaatc
     3061 aatgcctttc tcaactatat ccgttctaag tggtgaagct tcttttatac tttcatacat
     3121 tgtagctggt cttaaatttg caaataaacc caatgactct cttaatttta aaagaccaga
     3181 ctctggtctt ttatctccct tacatttatc ccactttggt cctccaacag caccaagcaa
     3241 tacagcttcg ttttttcgac aagtttcaac agttttatta ggtagaggtt ctccagtttc
     3301 atcaatcgcg catcctccag ctaatacata ttcacaatcg aatctatgat taaatttaca
     3361 acaaatttta tttagaacct ttataccttc atctataatt tccggtccaa caccatcacc
     3421 ttttatgact gctatattac aattcatact ccactacccc ctatttgctt ttattgagtt
     3481 aattaagcct tcatttaata taatattttg cataaactca ggaaatggtt ctgctttata
     3541 ttcttttcct tttgttatat tttttatcac acctgtagaa aaatctactt ctatattatc
     3601 cccttcatct atgttattgg cagcttcttc acattcaagt ataggaagcc ctatatttat
     3661 agagtttcta aaaaatattc tagcaaaagt agaagcaatc acacaggata ctccactttc
     3721 ttttattaca attggtgcat gttctcttga tgaaccacaa ccaaagtttt tagttgcaac
     3781 tataatatct ccttttttta ccttagagat aaatttatca tcaatatcct ccatacaatg
     3841 cgttgctagt tctttataat cagctatatt taaatatcta gctggtatta ttacatctgt
     3901 atctatattg tcaccgaatt taaaaacact tccattggca atcataaatt ttacctccct
     3961 taaattattt ctgatggttt tgatattttt ccagttatag ctgatgctgc tgctacagct
     4021 gggcttgcaa gatacacctc tgaatcaaca tgccccattc ttcctacgaa attcctattt
     4081 gttgttgaaa tggatttttc tcctgctgca agtataccca tatgtccccc tagacatgga
     4141 ccacaagttg gtgtagaaac tgctgctcct gcctctataa aagtggtaat ataccctttt
     4201 tctatagctt caagatatac tttttgagtt ccaggaaata tcataactct aactccatct
     4261 gctacttttt tgcctttcat tatctcagct actacttcaa ggtctgatat tcttccattt
     4321 gtacaagagc ctattacaac ttggtctatc tttatatcct tatctatctc atctactgtt
     4381 ctagtatttt caggaagatg aggaaaggct actgtttctt ttagtttggc taaatctatt
     4441 tcgtatactt catcatagac tgcatcttca tctgcttcat atatatttac atcttttgtc
     4501 atagttgaac acttatgtga atttatatat tccatagtct tatcgtctac tggaaaaatt
     4561 ccattttttg ctcctgcttc tattgccata ttacaaatag taaatctatc atccatagat
     4621 aagtattcta ctccatctcc acaaaattcc attgacttgt aaagtgctcc atcaacacct
     4681 atctccccta ttatatgaag tattatatct ttaccactta tccatttatt tggtttattt
     4741 ttcaaaacaa attttattgc tccaggaacc ttaaaccaac attttcctgt agccatacct
     4801 gctcccatat cagttgaacc tacaccagta gaaaatgctc ctaatgctcc atatgtgcaa
     4861 gtatgagagt cagcacctat aattacatct ccagcagtta ctataccttt ttcaggaaga
     4921 agaacatgct ctattcccat atctcctaca tcaaaaaaat ttacaactcc ttttgatttt
     4981 gcgaaacttc ttgtaaattt acattgttct gcactcttta tatctttatt aggtgtaaag
     5041 tggtctaaaa ccatcactac tttagtctta tcataaacat cttcaattcc taatttttca
     5101 aattctctaa tggctactgg tgatgttata tcattaccta aaactacatc taaatctgct
     5161 tcgattaatt gccctttctt aacttcattt aatttagcat gtttggctaa tattttctgc
     5221 gtcatagtca tccccatttt ttatttcctc ctcaatataa cttttattta ttgcattcat
     5281 aagtgcatta atagctgctg tatttatgtt ttccgatata cttacaccaa aatagacttc
     5341 attattgtgc tctattccta cataagctac ccctcttgaa tgtgaccctt cctctaatgc
     5401 atgttcccag taatatctaa atttataatc tttcatgcca cattgcttta gtgcattatt
     5461 aaatgaatct acaggtccat ttcctatacc aacaatcctt tgttcatttc ccatataact
     5521 tattcttgca gtcatctcaa tcatgttagt atcattagaa tcatcatttt catagtttaa
     5581 ttcatccatt gattttattt tatacttctt aactttataa gggctctcaa cttcaatata
     5641 ttctttctta aacaaattaa atattgcttc actactaagt tcttccccaa ttctatcaga
     5701 ttccattttg actacatttc caaaatcaga atgcatattc ttaggtatca taaatccata
     5761 atctgtttcc attatataaa cagctcctcc ttttccagat tggctattta tccttataat
     5821 ttctttgtat tctcttccaa tatcatgagg gtctattggt aaatatggaa cttcccagta
     5881 atcattatct ctgtttttca ttgctatcat gccttttcta atagcatctt gatgtgaacc
     5941 tgaaaaagca caatgtacaa gattacctgc atatggatgt ctatcatgta ccataagttt
     6001 tgtacagtct tcatatatac ctattatctt atctatattg ctaaaatcta gctctgggtc
     6061 tattccttgt gtataaagat taagtcccac atttactata tccatattcc cagttctttc
     6121 accatttcca aatagtgttc cttcaagtct atcggcacca gccaataatc caagttcact
     6181 tgcagccgta caagttcctc tatcattgtg agtatgcaaa cttagtataa tagaatccct
     6241 acaacttata tttttacaaa accattctat ttggtctgca tatacgtttg gtgttgccat
     6301 ttcaactgtt gatggaagat ttattattac ttttttttga ggagttggtt tccaaacatc
     6361 tatcactgcc tcacatattt caagtgcata atccatctct gttcctgtaa aactctctgg
     6421 tgaatattca aaagtaaatt ctgtttctgg atattttttt acttcttcat taaataattt
     6481 tgctccttca actgctatat ctattatttc ttgtttactc atattaaaaa ccacatctct
     6541 ttgaagaaca gatgtagagt tatataaatg tataattgct tttttacatc cccttattga
     6601 ttcaaatgtt ttttctataa gatgagccct agattgtgta agtacttgta tagttacatc
     6661 atctggaatc atattctcat ctattaattt tcttaaaaat gtatactctg tatttgatgc
     6721 tgatggaaat cctacctcta tttctttaaa tcctgtatca ataagcattt tgaacattct
     6781 gactttttca tttacactca taggtgttgg cagtgactga tttccgtctc ttaaatcgac
     6841 actacaccaa attggagcct taaatatttc attatctggc catttacgat ttactatttg
     6901 cattttatca tattttttat actttccaca cttcatgtta tttccccctt tttctgtttt
     6961 ttgtattcag tatacctcat atcgacgcaa tcctgcacaa ttcataagga taaatgtcaa
     7021 ttttatcatt agaataaaaa aaacctcatc tctaataaaa ttagagacga ggttttgctc
     7081 gcggtaccac tctatttagc tttctaaaaa gctcccttag taatagccaa tacaataatt
     7141 ataatgacta tatttcctat aacgtggaat tactccgatt attctaagat ttaaatctta
     7201 gaaaacagct cctagacaag ttcagaacta tcaactacta aatcacacca tcctttagct
     7261 ctctgaaagt ttcattgttc ttactacttc tattcatcac ttttttaatc atttaaattt
     7321 tctaaatatt ttgatttaat agttattata tacacattaa aatgtattgt caacacaaaa
     7381 aataattatc tcaatttttt atttttgata agcaattcta taaaacatgc taactattga
     7441 aaacagtatg atattatgcc ttaaactttt tcatcttttc atctatgata ttcaataatt
     7501 ttttttcatc ttccaaactc aatgccctta atctaatttt ataattagat tcgtcagtgt
     7561 atatatttaa tatatttttt actacttcta ttttttctat tatcttataa ttaaactttt
     7621 gactttgttt agattttata ctgaatatac attgattatt tattaatatt gaatgattat
     7681 cgagagtaat atatactttt ccctcatatt tatttgaaaa atcacgacct tgtttaaata
     7741 gaaaaactgc tgttattata cataaaatat ataatattgt cgttgaatat ataaaaattg
     7801 tagctaaaat tataagtgct aaaaccatat atatagtcat tcctttttta aaataaccat
     7861 tgtcataata attcatatag ataaacttat ttttactcaa attttttcac tcccaagatt
     7921 ctaaaaattt atatcaaaaa attctataat ttcatcttca tgataattta tgactaattc
     7981 atctggaaaa tctactgctt ctaaaacttt ttctgcattt tcaaattctc ctatagaata
     8041 acatatatga gagtcagtac caagaattac tcttgcacca tatgttttac acaatgtcaa
     8101 catatgactt acattttccc aagtacccgt tctatgagaa tttgaactta atgatgaatt
     8161 atttatttct aaaaggatat ttttatcttt agcttttttt actataggtt cataatctaa
     8221 aggataccta ctgtcatctg gatgtccaat tatttttacc ttaggtttat ccataacttt
     8281 taaaatagca tttgtatttt cttcttttgt accagaagct atacaaggtc tatgcaaact
     8341 tgcgattata taatccaaat gttgcaacat atcttcttga acatctaaat taccattata
     8401 atccattata tttccttcta ttcctctaag aatctttacg ccttgtactt cacgtggaag
     8461 caaatgcaaa ttataaaaat agaatggatg tggtcctcct ggcatattag gtccatggtc
     8521 tgatattcct aagtatttta tattcttctt actcgcctct tcgacatttt ccttgaaagt
     8581 actatgtgca tgtccactta ttagagtgtg acaatgtaca tccataatag actttttcat
     8641 taaatttcct cctaatattt tacataaatt cgtgaaaata gctaaagggc tatttcaaaa
     8701 ctaaagctgt cataatagac agtgtaacgt tttaaaacag ccccattttc aattatttta
     8761 cacttctaaa tctttaaatt tatctttaaa taattctcca atacttccta aagattcctc
     8821 tacttctagg tattctgtta tatcctcttc tggctctcta gttgcttctt ttattgaaac
     8881 caacattctt ttagtctttg gtttaaaatc aagaatctta actttaacct catctccaat
     8941 attaacaaca ttagtaactt tagccactct agtatcactc aattcagata ttggtaaata
     9001 cgcatctaca ccttctttaa tttgaacaaa agcccctttt tctattattc taagaacttt
     9061 agcattgaca acatcatcaa tttgtacttc ttttgctatt aaatcccaag ggtcattatt
     9121 tatgtctttt aatgccaagg caattttttt agtctcttta tttacatcca acacataaac
     9181 ttctacttct tgtccctctg aaacaacatc ttcaacactt tcaactcttg tccaagctaa
     9241 attatttata tgtgctaatc cttcaatccc accaatatcc acaaatgcac cataaggcat
     9301 tatctttgtc accttaccat ctcttttttg tccaacttca agagaattaa ataagtcttc
     9361 tttagctgct ttgatacgag ccttttcttc ttctctttct tgcttaattc ttgctctttc
     9421 agcttctttt tctgccttaa tttgagctct tctttcttct ctctctttat ttatacgctc
     9481 ttgtaataca tctctatgag atgctacaag tctatttttt ctaacatcca attcttttat
     9541 ataaacttct aagttaagac caacaaattt agatgtatct gtaataaatt ttgtatcaag
     9601 ttgagaaatt ggtataaaaa atgtatatgt attgtaatta gcaaatacac ctttatctat
     9661 attcttttca acatttacag ttattattct atgttcatca taagcctttt gtaactcggc
     9721 aaaatcattt cttttgtcaa gttgtaattt agataaagtt attgtaccat ctttttgaga
     9781 tacttttgtt attacagcag ttatttcatc acctatgtgg tatatatctt ctatatattg
     9841 atttttttct atgttcaatt cacttatagg tattattcca tcaaacccat agtctaatcc
     9901 taattgtact tcatcatttc tcactgcagt tatttttcca gttgtcaatt ctccaacttt
     9961 cactttgctg aatacttgtt cttgctggtc aagtaattct tgcattgtta aatcattttc
    10021 cattataaac atcctttcct cttattgatt atcatatctg taaatattat accattaata
    10081 ttgcaaatac ttacattttt cttactataa tttttaaaat aaattcaact tcatatattt
    10141 atacattata gaaaatatct tattaaatta aaatacaaat tctaattttt atctaataaa
    10201 atattttcat aaaaaattta tattgtatat cttattcttt tattgcttta ggttttgata
    10261 gaaaacattt ataaaatata aagaaagaaa ttgctgttat agtagcagct gttatatctg
    10321 caactggctc tgctaaaatt actgcaaaaa gtttttcatt aaagaatgtt ggaagtataa
    10381 atattaaagg tattaaaagt acaatctttc taagtagagc taaaaccaaa gatattgttg
    10441 cttttccaag tgctaaaaat gtctgttgac aagctatttg aatcccaaac ataaaagcac
    10501 cagcaaaata tatttttata ctccaactag tcatactaag taactgcgga ttcttattaa
    10561 atatactaac aaaaaatgca ggaaatatca ttaataaaag ccataaaata gtagaatatg
    10621 taaaacatga caataaacac aacttaaatg tcttttttac tctatcaagt tgacctgaac
    10681 cataattata acttattatt ggttgtgctc cttgtgtaac ccccatatta ggaagcataa
    10741 gaatttgcat tatactgctc attatggcca ttgaacctac tgctaaatct cctccataca
    10801 tttgtaattt actatttaag gctataagta ctaaactttc tgtagattgc attataaatg
    10861 gagagattcc caagccaagc actggtaaga tgatacttgc ttttggtatc atatacttct
    10921 tttttatttt aagtatactt ttctttccaa agagaaacat aagcacccaa atagcagaaa
    10981 cgccttgtgc aattatagta gctaatgcag ctccttttac acccatatta aagccaaata
    11041 taaaaatcgg gtcaagtatt atgtttatta aagcacctat agcaactgtc atcattccag
    11101 ttgtagcaaa cccttgggta tttataaaag tattcatacc cattgaaatc tgaacaaaca
    11161 ctgtacctat taaataaata tttaaatagt ccattgaata tccaattgta gattcacttg
    11221 ctccaaacat ccaaagtaaa ggctcttttc caatcttaaa acctatagtc aaaagtattg
    11281 ctaaaatcac cagtacagaa aaactgttac tcattatttt ctctgcctca tcattgtttt
    11341 gctcacccat ttttatagca gctaatggac ctcctcccat accgattaaa taactacatg
    11401 cagttattat aattattatt ggaaatgcca ctccaacacc agccatagca acttctccat
    11461 tttccattct accaataaaa atcctatcga ctatgttgta taaaacattt acaatttgtg
    11521 cgataatagc aggtgtagca agtttaaata ataatttacc cacactttca ctacctaagt
    11581 tagtgtttga attttccatt ttaaaacctc ctcaatccaa taattaaaat gtatcactaa
    11641 aattttattc tatataaaaa tttcatttta ttagcagaca aatttagagt actttcccta
    11701 caagtaatac tatactatat ttcttttgcc atagtaaaca ttttagaact aactgaagtt
    11761 aaatacttta tctcattttt tatttattat taaaaatttt tcacatatac tcataaaaaa
    11821 actatccaag tatattactt agatagtttt atattatatg taaagaaaga gctgaaacta
    11881 taacccctga taacaaatta ccaagaaata ctcccataaa agcatctttt attctcattt
    11941 ttaatatgga agctatagca gatgcagtcc atgttcctgt agttggcagt ggtataccta
    12001 caaatagtat tataccaatt atcgaaacac tttttaattt cttcattctt gagtttattt
    12061 ttctatcaat tacatcagca atccctttaa atagtttctt ccctcttaaa aattgcaata
    12121 catgtctgaa tgtcaatatc aagggaatcg ataccaatgt agaacctatt acactaaata
    12181 cataaaccca tataggattt aagcccattg caatacctat aggaatggct cccctcaatt
    12241 ctgttacagg aaccatagat aaaattaata tgtgtaaata tcccaaacta ttccctccta
    12301 ttctaagtga cattaagtta tgaatttatt tgctctataa cctcaccatc ctttttacta
    12361 actaaaaatg catttttagt caatgaaagc attggtaaat cactcttaga gtctgaatat
    12421 gcatatgaat tttcataatc aatctctatc ccaagtttac ctaatacagc ctttattctt
    12481 tttacttttt caattccctt acagttttct ccaatgaatt gatttttata tcttgaattt
    12541 tcataaaaaa actccgtgcc tataacctcg tctgcaagac cataatactt aaaatatttc
    12601 atatatgcat atggagatgc agttatcata attataacat tatcttcttc tttatttttg
    12661 taaataacct ttttcataga ttcgttaatt tttttcatta tgcaatcatc aaaaaacttt
    12721 tttaaatctt cttcactaaa atctactatt ggataaaaga ttgcctcttt tgccttcttc
    12781 aaaggtatca ttctaattaa atacataaat agaataaaaa taatgtatgg caactttata
    12841 atagttttaa aggttttatt ttttaaagag taaataaaaa aatctatcat gctatcagta
    12901 tttataacag tataatctac atcaagtaat aatacacttt ttttcataag tatttcccca
    12961 tcctatcact aaaaatatca ctaaaaaatc aatattatta aacatgtaat tatccataag
    13021 attacgttta tttttaaagc attatctttt aggacaatat cagtaggatt attttcattt
    13081 gtagtgttaa ttatataatt atatctaagt acaccataaa ctacaaatat tgttgtaaat
    13141 atcatatgtg gcttttctgg attacttgta gaatacaatg cataacatac aattgtagaa
    13201 cttaatataa ctatcatcat ttgatttaga ttttctatgt cataatcttc caatattttt
    13261 ctatgttcaa ctgcatcatc tcttaaagtt tctatttctt ttttacgttt tccaagagct
    13321 aagtacagag ataagaaaaa tgtacataaa attatccaat ttgataaact aacacttatg
    13381 gctacacatc ctgcataaac cctaagtata aaaccaagag atattgaaaa cacatctaat
    13441 agtattatat tctttagttt aagagaatat aatatattgt ttatcaaata gagactgaga
    13501 attatagaaa gattaaaact aacaactgtt gataaacaga ctgaaattaa agctaatact
    13561 acaaatagta tattagcact ttttttgctt attcttccac ttgccactgg tctattacat
    13621 tttttaggat gttttttatc tttatccatg tctatagcat cattcagtgc atatactgat
    13681 gatgacatta gacaaaaaca cacaaacgca ataaacgtat ttaaaaataa atttatattt
    13741 agtatgttgt ttgaaaaaat tatagctgaa aatacaaaga aattctttat atattgcttt
    13801 attctcatta actttatata atctgaaatt ttagtaagaa gccttatact tgtattggtc
    13861 tgtttcataa acttactacc ctttcaatat tattttttaa acaggatatg attttatccc
    13921 tatgtttaaa atttctataa atccattgac attactgatt actatagtaa ccaataacag
    13981 cgatagaaat atattataca tattcttttc attttttcta agcgctttcg taaagtaagc
    14041 caataaaatt ataactgcaa aactaaaatt tatagccata atacttgaat tgactagatt
    14101 atatcctact ataccatgta aagttagatt gaatataatt attcccatac atagcttagg
    14161 aactcttttt tctgaatttt caataactga taaaacacaa aaacataaag ctaataatgt
    14221 aagaattact ggtattgtag caacttctcc attttgcaaa aataaccctt ttttaatact
    14281 tgctccagga aaataaaaaa ccgaatacaa taatctctct ataatcattg caatcttttc
    14341 caaaattggt tctccactta taaatttcgt atcatactgt attacatttc caaggttcat
    14401 aaaactctca taagactttg ttgaaactac acaaatatat gccattagga taaatgtaat
    14461 taaatgtttt aacatttttc ctatttttaa tttaaactca aatatcatat taaaaaaata
    14521 caaatatata ttactaatag ttattccaaa tagaggaata gctgctaatt ctactaaata
    14581 agaatttttt cctttcatct tatttgcaat aactatgaaa aatattaatg aaaattggct
    14641 atatataaat ctctctacat ttaaagtcat aaataactgt ggaaaagaaa atatcattat
    14701 catagtaagt aaaattaaag ttaatctctg catttttatc tttttaatat gattaaagac
    14761 taaagttatt gacatagcac tagttattat ttgtagacaa attagtccaa acccataggc
    14821 actattaaaa tctgttgtcc caggatttgc tattgaagta caaaataggt atattggata
    14881 tgcaaaaatt gatataattg ctgaaaacaa tatgtgctta ctattgtctt gacttatagc
    14941 aaatacattt aaattgaata aaactcctgt atctgtatct aacaatacat cataagtatt
    15001 gtttaaatca taaaatatag tagtcttaga aaaaaatatc ttagttatta ttaagtaagt
    15061 tattacaact aatataaaca aaaacatctc gtttttatat tttaatattt tactcatcaa
    15121 tatatcacca tccattcatt atataggatt tgctgacacc tacaatttat tccttatatt
    15181 taatagccat cttcataatg ttcttacttg ttttattgta attgaataac tctttattta
    15241 caaccacaat atttacttta ttgatgttat aatcagtcaa gtattgttta tataacatag
    15301 attagtgttg tataaaatga gaatttgtaa gcaatattaa tgtaaaatat ttgaaaaact
    15361 ttatataaaa atatacaatg ttgcttatgg aattaaacta taacaaatta aagcataatt
    15421 taaggagaca aaattataat ctgtctcctt aaatattaaa actatatttt aaaacattac
    15481 taaatactat acaaatttca aatatagtat aaaattaatt agactttaac actattagct
    15541 ccatcttctt cccatttttt aatttctttt aatctatcta ttataggtaa atgctgagta
    15601 cattcaactt cacattttcc acaagatata cattctttag cttttgcctt actattcatt
    15661 gtgtaattcc aatgtcctaa gccataaact aactttgtca tttcttcatc actcttttta
    15721 aacatctgct tttcattata aaaaagcata taggctgggg tattaatacc ttttggacat
    15781 actttacaat aaccacaacc tgtacatatt tcgttcatat tcttatttaa tctagtctca
    15841 atatcatgta tatcctcatc tgaataaatt ctattttcgt ctgcaatttt acatgcatca
    15901 tctatatctt gttttttatt aaaccctatc aaagatatac ttatttgtga aattcctatg
    15961 ttgaatctta aagctgattc tatagtactt tcgccatctt ttgatagaaa agaaagttct
    16021 ttattatact ttggaatagt tccaccactt aatggattca ttgccacaac accatatcca
    16081 ttatcaacag catatttggc accttttagc ctatatggaa agtttaatat atttattccc
    16141 atagttacac cttcaaactt attttcactt agaatatcta taacctcatc tcctggttga
    16201 tgagatgaaa atactatatg gtctatcaat ccttcttctt tacatttcaa taatccttca
    16261 tattgacctc caggtctcat tgctagttcg taatgttcca tctttctaat attccaaaca
    16321 tgataaaaat ttattttaga tacgcctaat cgttctattg atttttttac agcctctata
    16381 gctttttctg atgtatcaca tgcttttggc ttttctttag ttgatacata aaaatcggtc
    16441 ttaccttcct ttatcatttg tctaaaggct agtccaaata tatcttcact tctgtcatca
    16501 caataccctg gtgctgtatc aaagtaatta ataccttttt catacgcata tttgactaaa
    16561 tcagcatttt cttgattact tttttctaaa tcaaacctta atcctccata gccaactact
    16621 gaaaccattt tccctgtctt tccatattca acgtatctca ttgtaaattc ctccttagat
    16681 atattaagac ttaatttctt tatagaaaat attataccat aaataatttt tataaattat
    16741 ttatggtata atattttttt tataaattat atttttttat aacttgtatt ttataactaa
    16801 gttaaaaact ataaaaaggt tcaatatgga ctattacttg agcattttca ttaatttctt
    16861 cttgtatttg tttctcaatt ttatgtgtta aatcatgaga ttgctctacg cttataaatg
    16921 ggtctaccat tacatgcatg tcaatataaa tagaactttt gctacctcta cttctgatat
    16981 tgtgaacatc ccttacctca ttaaattcaa acacaatttc ttttatataa tcctcatcta
    17041 cagccactct atcgaccaaa attccaatag atggcctaaa tattccataa gccgaataaa
    17101 ttatgaatgc agaaataata ataggaacta tagattctat tattactgga aatcctaact
    17161 taacaccaac taaagtaacc aatacaccta gagacacaaa tatatcactt cttgtatgca
    17221 atgaatccga aatcaaaaca taactattta gtttagtccc aattctatat tcatacatgc
    17281 atacaaaaat atttataaaa agtgtaataa ttaaagcaat taaactttct atagttatag
    17341 caggtacaac tggattagct attcttaaca ctgcactaag aattatctta attgctataa
    17401 caaacaacat accacttata aataaactgg ttataatttc aaacttttta tgtccataag
    17461 gatgattttt atcttttggt ttagatgcaa agaaaatacc tataagcccc actatattag
    17521 atgctccatc tgacaaagaa tgaaatccgt ctgctgtcat actatagctt tttatttgat
    17581 taccaataat gatttttaat aatgctactg caaaattagc aaataaaatt atccacaata
    17641 cttgcttcac tttcttatag ttatccataa caaattcccc ctcccttcga ttcaataaag
    17701 aaagctatct atcaatatca atcaaccaga caataaaatc gtatataagc acatttacta
    17761 tatttatatt caaaattggt tgtacttgtt cattctattt gaaacttaat tataaataaa
    17821 aatcgtaggt atggttttgg tatacataaa aataagagac tgtctcaaaa taaagataat
    17881 cttctttttt attgttgaaa tgataaaata tatttgattt catataaaaa agagtgcctc
    17941 atgaactaaa aagttcattt tgagacactc ccttaaattt ttgatataaa ctattaattt
    18001 tttatactaa gccttcttta actaagaatg aatgagcaac ttcttctggt gatttaccaa
    18061 gttcatccac ttgataatta agttctctca tagtttcttc atttattttt cctgaaagca
    18121 tattcataac tttttctaac tcaggatatt tcttcaaagt atcttctctt actaatggtg
    18181 ctgcataata tggtacaaag aaatttttat cgtcctctaa tatcttaaga ttaaactttt
    18241 taataagacc atcagttaaa aatgcatcta taacctgaga ttcattatta tctaaagctg
    18301 tatatcttaa acttccattc attgctttta catctttgaa ttttaaacca taatctctag
    18361 aaagccctac aagaccatct tctctatttt caaactccaa agttggtgag aatgtaaatt
    18421 ctttaccata tttagtcaaa tcagaaatag tatttattcc atacttttca gcagtttcag
    18481 gcatcatggc taatgtgtaa gtattattaa atccaagagg gtcaagtaaa gttaactgat
    18541 tttctttttc catagtatct tttacaacat tatatgcttc atcagcatct ttaatcggag
    18601 catgtctcat tacatttacc aaaagtgtac ctgtatagtc aacatacatg tctaactcac
    18661 cagatttaat tgcattaaat gcaacagatg aaccacctag atttaaattc ttcttaactt
    18721 taagattcgt atttttttct actaattcag cataaacatt gccaagtata agttgttctg
    18781 tataatcttt agaaccaata gttattgtat cttttttact tgaaaaacta gaactaaaaa
    18841 caacgaacaa cattgaaaca acaaccacta cagatattac tttaagtgct atataattct
    18901 tcttaggtgc ttttggattt aatccttttg gagtaactgc aacttcaatt ttactaaata
    18961 aataatcaac taacagtgca attatacatg atgggattgc ccctgctaaa atcatattat
    19021 tatttacagt ttgaacccct gaaaatacta aatatcctaa accaccagca cctataaatg
    19081 ctgcaagagt catcaaacca acagctgtaa ctgcagatat tctaactcca cccattatta
    19141 taggaagtgc taaagggaat tgtattttaa ataatgtctg atttcttgta agaccaatac
    19201 ctttagctga ttctaatact actgggtcaa tacttgttat acctatatac gtatttttta
    19261 caattggtag taatgaataa accactacca taaatatggc tggtttactt cctataccaa
    19321 gtataggtac aagaagaccc aaaagtgcca tagacggaac tgcttggact aagtttacaa
    19381 atccaagtac aaactttcta agagatgaga ttcttgaaat aattattcca agaggaacac
    19441 caactattat agctattaaa atagatgtaa cagttagact catatgttgt attaaaagct
    19501 ctataatctt atctttttgt aatagtataa agttaaaaaa attagccaag aacactcacc
    19561 tccatttcta agaattgttc acttaaaaca gaaagtaaac tacttctagt aataagccct
    19621 accagtttat tttcatcaga aataaccgga atatatccaa ccgaattacg attcattaca
    19681 tttagtattt ctactaaatt atcaccttca tttacatgca aaggctcact tgacataata
    19741 tcagcaagta atattgactt atcatcaata tctttcatat cttttacagt aacaatacct
    19801 tttaatgttt ttgctctatc tataattagt aagctatcaa ccttactcgt tctcataatt
    19861 tctattcctt gagttacagt tctagtagaa ttaacagcaa taggattttt tatcataata
    19921 tctcttgctt ttatatattc tggattatcc caaactctat cttctccgat aaaatctttt
    19981 acaaagtcat ttgcaggctt tctaagtata ttttcgggag tatcatattg tgctattctt
    20041 ccatccttca taatacaaat tttatcagct atctttaaag cctcatccat atcatgcgtt
    20101 acaaatatta tagttttttt caattcatct tgaagagaaa ataattgttc ttgtaaagat
    20161 gttctcgtta ttgggtctaa agcactaaaa ggctcatcca tcaatattat ttcagcatca
    20221 gtagcaatgg ctcttgcaac accgattctt tgttgctgtc caccactaag ttctgaagga
    20281 tacttattca aaaattcatc actatcaagt cctaccatct caagtagttg caacgttctt
    20341 ttttcaattt cttcaacgga tttttccttt tttaggcgtg gaattagctc tatattttct
    20401 tttattgtaa gatgagggaa taggcctgtg ttctgtataa catatcctat ttttcttcta
    20461 agctctattt cattttcctg agaaattggt ttgccattaa tatatatctc accagatgta
    20521 ggttttatta atttgtttat aagcttcaaa gtagtagtct ttccacaacc acttgaacca
    20581 atcaaaacta ccaatgtacc tgtttctaca gctagagaaa tatcatctaa tataacatta
    20641 tttcctattt tttttgttac atttcttatc tctatcataa tttatcatcc cctttttcga
    20701 acaagcaacc ttcttcaata ttataagttg tttttataat tatatcatac tattttattt
    20761 atgtaaacaa agtacgattt ttaggtcact atttgtctga atattgctac aaatataaag
    20821 tatttatata tagtatataa tatataatgt caaaaaacaa aaaatataaa aatattcata
    20881 aaataacact agcctcaatt atatagtatt aaagctagtg ttatttcatt taaacaaaac
    20941 tcacatttgg atactatcca tgtattcaaa taatgtaata tctttataag tttctttttt
    21001 atcacttagg tttgatattg taactcccaa tagcctaatt tgttttccat taacctcaac
    21061 atttctcaac aaattatcta caccacttct tatatcatta tattcgtcaa tatagtgttc
    21121 taaactaagg cttctagtta tctttgtaaa gtcctcatat ttaattttta atgttaatgt
    21181 ttttccaaac ttctcagagt tttttaatct atgacatact tcttcacaaa gttcatcaag
    21241 aatgttgcgt gtttcttctt catcaatatc caaattatga cttaatgtag tctcagcccc
    21301 aacagatttt ctaaccctat ttggttccac tggtctatcg tctattcctc tagcaaattt
    21361 atataattca taacctcttt ttttgaatat attttcaagt tcaaataaat ttaaacacct
    21421 taaatcatat ccagttttta tacctaaatt tttaagagta tttgaagtaa cttttccaac
    21481 accaaaaaat ttattcacag gtaatttatc taaaaagtcc tgggcatttt cttcggttat
    21541 tacagttaac ccatttggct ttcttaagtc tgatgcaatc ttagcaagaa acttattgta
    21601 tgacacacca gctgaagaag taagaccaac ttctctaaat atatcttttt ttatttgctt
    21661 tgctatctca attgatgaat caatattttt tttatttttt gttacatcta agtaagcttc
    21721 atctaaagat aatggttcaa ctaaatccgt gtatctataa aatatatctc ttatttgctc
    21781 tgacacactc ttataaacat caaatcgagg tcttacaaaa actgcatatg gacacctatt
    21841 gtaagctaca gctgatggca tagctgaatg gataccaaat tttctagctt cataagaaca
    21901 cgttgcaacc acacctcggc tttgtggatt tccaccgaca ataacaggtc ttccttttaa
    21961 ttttttatta tctctttgtt ctatagatgc ataaaaagcg tccatatcta tatgaattat
    22021 ttttctataa tgtttcatta ttatcacctt ttaaagtata aatagattaa ttttatttat
    22081 attacttttt aattatacca aacttatgtt tctttttggt attttttcat tattttcttt
    22141 atatattcat attttccata aataaaacca tctataatcc attaacttca atataattta
    22201 taaaaaatcc ttaaaaacac ttgcaaaaac tatataaaag ctttacaata ggtattccaa
    22261 ggaactaaat ttaaaattcc ttatggataa cagtatatat atttaattta tgggatgttt
    22321 taaaaacaaa agactgtctt atacaagaca gcctactgat tttattataa ttgtaatgga
    22381 ctgctcaaac tattacttta aaacagccca tattttttta tataatttta actatagtaa
    22441 agattttgtg aaggatattc tgggtcacaa gttacatcta taccaagctt tctaaatgtt
    22501 tgttcatcat ctctatttaa tatagtagta gaatgagctt gacacccttt taataatgct
    22561 aacttttcca tagcaaattg tgcagttgga ttagttacag cacaaatact aagtgcagtt
    22621 aacacctctt ggcaactaag tgaaacattt ctactagcta aagtctttgt ttttaagttt
    22681 atgataggtt ctaatattac aggtgatatt aagtgcatat catcagatat attggctaaa
    22741 tgtttaatgg catttaatac tactgctgca gttccattca ttaaatcaga acccttacca
    22801 gttaatattg taccatcttc taattctaat gcaactacag gacaagtatc attcttgtcg
    22861 gcactttctt tcaatttatt actgtagttt ctagcaggta atacaacatt tctatcttct
    22921 ggctttaagt taagctcttc cataatcatt ttcattctat cataagcacc tttatcaact
    22981 tgtccctttt tatactcaca ggcagtttta aagtatcttc ttattatttc ttctatagaa
    23041 gcttttctta ttacttcatc atctattatt ccaaagccaa ctctattaac acccatatca
    23101 gttggagatt ggaaaattga ttcttttcca gttatctttt ctattatttt tttaagcact
    23161 ggaaataatt ccaaatctct attgtagttt actgacattt caccatacgt ttcaaggtgg
    23221 aatgaatcta tcatattcac atcttttaaa tcaactgtag ctgcttcata agctatattc
    23281 aaaggatgtt ttacaggtac attccaaact gggaatgtct caaacttaga atatccaact
    23341 acattacctc ttttattttc atgatacaac tgacttagac aagtaccaag ttttccacta
    23401 ttaggtcctg gtgctgtgac tactactatt ggctttgtag tttctatata ttcatttgct
    23461 ccatatccct catcactaac tatagtctca acatctgatg gatatccctt tgttggataa
    23521 tgcttataaa ctttaattcc tctacgttct aatttattta taaatacagt tgtagcaggt
    23581 tgtccttcaa atctagtaat tactacacta tttacatcta gttcataacc tcttaaatca
    23641 tctattaatc ttaaaacttc catatcataa gtgataccaa agtctcctct tattttgttt
    23701 ctttctatat ctcctgcata gacacaaatt acaacttcaa ctttttcttt catatgttgt
    23761 aatactttta tctttgcatt ttcatcaaat cctggaagta ctctttttgc atgaaggtct
    23821 cccatcaatt ttcctccaaa ctctaaataa agtttgtcaa aattatttac tctttctaag
    23881 atatatttag actgctcttc taaatatttt ttgtggtcaa atcctacttt catcttaaca
    23941 cctcactaaa ttaaatttct tattgataac agtatattta tatatatttt tttagtaaaa
    24001 catcttataa aaaaatgtta atactttttc actcaaagta atattataca attaagatta
    24061 atttttttca agatagtttt atggtaaata agatatacct aaatataact aataaaataa
    24121 gaatattata tttttatata taagtataat attctcacct tagcattaat ttatttcaat
    24181 attttcatat atcttttatt ctaaattcaa tacttttcta atatcttcta taccttgata
    24241 aacttcttgt ttagaaaaat tcatagcttc taattcttca tcagtctttt ccataagcat
    24301 agtataaaat tctattgcta tatactgcat attttcacta tttacactct tagctttatc
    24361 aaataaaatt tcttctgctt cgtttacatt tccctgaaaa actaatcttt ttaaagttat
    24421 aagtataact tcttcttctg tattatacac taaatctttt tcttcatatt cactgtactt
    24481 ttttcccaat aaaagtcttg caaccataag ttttatctca ttgaaaatct tatccactat
    24541 agccattttt acatctccta taaataaatt ttattttctt tttaattata tcagacttta
    24601 tcgtaaaaat tattatatgt aaatgaaata attcaaaaat aaattttaac aataaaaaaa
    24661 agaaggtagc gggggatttc cgactacctt caaacactag attgtgattg gtttggtatt
    24721 ttatttatac ccaccataag ctttattaaa tcatctaaat tgattttttt agcatccaca
    24781 tcctccatca aaaacgtcac cacattcaca aagtattaat aataatatta agaaaggtat
    24841 ccatgcacat aagtccattt cagcccaaca atcttggaat gctaagaata agaagaataa
    24901 tattattatc caccaagcac atccaccaaa tccgccttca ccaaaaaatc tatccaacat
    24961 aatatgttac ctcctagtca ttttgtatgt ggagtttcag ctcctaaaat atactatgtt
    25021 taaggggtaa tatttgctaa tgattttttt aaattttttt agatattttt aaaaaaatta
    25081 ttgattcaca ctcaatgtct taccatcact attgataact acctctccat tagaagtcaa
    25141 aaaggttttt atattcaatc tttccaatat ttttaaaaca ccttcctctg gttctttttt
    25201 ctctgaacat gtaataacag catattgggg tgaaatagac tctaaaaatg tttcagttaa
    25261 tttgtcatat cttccatgat gaggcatttt aacaaaatca tattttaaag tatttccatt
    25321 tataaactct gacaatcttt cttcctctgc atctcctgca aataaaaact tatgtgctcc
    25381 atagcttata ttagtgatta ttgaataatc atttgaactc tcgtacttgc tttttgaagc
    25441 cggatgtatg tttatttctg cactattgat tacaatattc atattatctt ttagtagcac
    25501 tggttctata tcagcttttt taagtgagtc aatatattca tcatattgct tactatcttt
    25561 cttataattt gcttgtataa tattctttac tttaacacta gataacacac tatctactcc
    25621 acctatatgg tccttatcta aatgagttaa aattaaatag tcaagtgtat ttattccttt
    25681 ttcttttaac ctatccacta tttgttttcc atttttatct tctcctgtat caatcattat
    25741 gactttgtta cctatctcaa ccaatatgca atcagacttt ccagtgttta gtatagtagt
    25801 cttaaatgca gtattttttg tgctactctt tgtgctcctc tggataccat tttgcctcac
    25861 actatttttg tcacttttta aataagattc acttgttgat tttatcttac tattagtagt
    25921 tatatttgtt acaagcaata atattactat tatagataat gtagtaacta aaaacaggat
    25981 atcttttaat actattttcc tcatccaaaa gctcctataa attttattta ttacatattt
    26041 atagtatagc aaccttaact ctgtaaaata cacatataaa aagggcaaat tttaggcata
    26101 tttgtggcat aataaaaaaa tgactgtacc aaaacaatta tctttctaaa tttacatctt
    26161 caaattcttt aatcttatca ttagataaaa cactcttttt agtagattgt ccattttttc
    26221 tatcaaaagt atttttagct tttacacctg ataaaaactt acctgctcca ttaatacaac
    26281 cttcttcaca catcattcct tctataaaat taccttctaa tcttcccaat ttagccattg
    26341 tcattgtctt tttaatttgt cttggaccag atacttttat aggttcaaaa tcaaaactaa
    26401 gccccttttc agcaatatag ttctgtactg atttggcaag tccaccagat gctccaaatc
    26461 cccttccaaa aatcgaacca tcatttatat cttcatttga acattttgat aaatctatat
    26521 taaatgcttc aaataatgcc attagttctt caaaagtaag tacataatct actgaatctt
    26581 ttaaactttt ctctgttgcc tcactctttt tagctgtaca tggacctata aatacaactt
    26641 tagcatcaga atctattttt tttactaatc ttcctgttgc taccatagga gacactgtag
    26701 atgatattct atctttttca tctgggaaca tcttctctat atacttaaaa aatcccggac
    26761 aacatgaatt tgtcatgtaa ttatctcctg attttattct ttcaataagt tcattgcttt
    26821 catgaactgt aactgcatct gctccacagg aagcttctat catatctaca aatcccagtg
    26881 attttatagc attttttaac tgaccatatg taatattact atctatttga cctgttatag
    26941 ctggagctac tattgcatac atattttctt tctttgcaag tttttttgca acaggtgcta
    27001 tcaaactctt atcagatatt gctccaaaag gacatgctga catacatgct ccacaattta
    27061 tacaattatc ttcatgtatc attgctttca tagtgtttct attaaaatcc aaagctcctg
    27121 ttggacaaac gcttttacaa ggtcttacaa cttctgatat agcatcatat tgacatgaac
    27181 ttttgcacat tccacaagcc ttacataaat catgatttat atatgctctc ccatttatat
    27241 aagaaattgc cccaaattta catgcttcct tacatctatg agccaaacac cctctacaaa
    27301 gctctgtaac tgtaaattca tttattggac atctatcaca tgctgcttca actatatata
    27361 taatttgctc atctgtgtcc aaactaactg aatctggatt tatatctcca tatttactat
    27421 ttggagttaa acttaatgca agttgcgccc tttcaagaac tacttctctc tctttataaa
    27481 cacaacatct atatctcgcc ttttctcctt taattatttc atatggaatt ttttctatat
    27541 tttcttttgt taaattttct tcaatagata gtcttgctac tgctgttaaa acttcatgtt
    27601 ttaacctttt tagttgcgtt tcaaattcaa acataagtaa tcctccctat aaatcacacc
    27661 tttttgctat atttctacta ttatgtatat tgtatttttt atttatttct ataaattatt
    27721 ataacatagg catatacttt gttaagttat atacaaaata ttatatatgt aatttttatt
    27781 ttaagtgtat ataattttta tttttgttgt tcaataatta aatatataaa taaaaataga
    27841 gttgtccaaa agttaaactt caacttagaa caactctatt aacaatatgt atttttgttg
    27901 ctttgtatta tctttatttt tctaaattta tattactaaa atcttttatc tttgtatttg
    27961 ctaagacact tttcttagtt gattgagaat tttttctatc aaaagtggct ttaacctttg
    28021 cacctgataa gaatttacca gaaccattta tacaaccacc ttcacacatc attccttcta
    28081 taaaattacc ttctagcttt cctaaattag ccatagtcat agttttcttg atttctcttg
    28141 aaccagaaat ctttacaggt tcaaaattaa caccaatacc tttttcagca agataatttt
    28201 ctatagcttt tgtaagacca ccagcagctc caaaacctct tccaaaaatt gatgcatcat
    28261 ctatatcttc atttgaacac ttagccaagt ctatatcaaa tgcctcaaat aatgccatta
    28321 tttcttcaaa agtaagtaca taatcaacag ctccttttaa ttctttctta gctgcctcac
    28381 tctttttggc tgtacatggt cctatgaata caactttagc atctggttca tgacttttta
    28441 taaatctacc actagctatc ataggagaca ctgtagaaga tatttttcct acatgatttg
    28501 ggtatgtttt ttctatataa ccaacaaatc ctggacaaca agaatttgtc ataaaagctt
    28561 ctcccttttc cattctttca gcaaattcta agctttcatg aactgtaact gcatctgctc
    28621 cacaagctgc ttctaataca tcaacaaatc ctagtgattt tatagcattt tttatttgac
    28681 catatgtaac atttgcttca acttgacctg ttatagctgg agctaccacc gcatacattt
    28741 tctctttttg aactaacttt ctagctacag gagctatcaa actcttatca gatattgctc
    28801 caaatggaca tgctgacata catgctccac agtttaaaca tttatcctca tgtatcatag
    28861 ctttcatatt ttctctatca aatcctaagg cattagttgg acaaacactc ttacatggtc
    28921 taacaacctc tgagatggca tcatattgac aagctttttt acacattcca caagccttac
    28981 ataattcatg atttatatag gccattcctc cgacatgtgt tatagctcca aatttacaag
    29041 cttctttaca tctatgtgct agacatcctc tacaaatatc tgttactgta aattcattta
    29101 ttggacaact gtcacatgca gcttccaaaa tatatataat ttgttcatct tcttctatat
    29161 ccattgtatc taaatctatc ttatcttgac ctggttgtaa ccccatactt acatttactc
    29221 tctcagatat tatagctctt tctttataaa cacagcatct gtatgtaggt ttctcacctt
    29281 ttattatttc atactgaata ttatccattg cttctctggt aaggttatct tcttttccaa
    29341 gtctagctat tgcagttaaa acatcatgtc ttaatttgtg tatttgtgtt tcaaattgaa
    29401 acattttaat accacccccg taaatgattt tatacgatac cattataaca caatatgtcc
    29461 ttttattaat atatacataa aatattatat gtttaaattt tattttatcg aatatatata
    29521 gtgttttttt gttttattat ataatattat tgatatttct gaaatttcac tatttttatt
    29581 tttacttttc aatctaatat ataatatttt ttattatata ttttaatttt gctttttact
    29641 tacatacctt tttgttacat tttttgatat taaatttatt atctacatt
//
LOCUS       DAEOTL010000044        28909 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEOTL010000044 DAEOTL010000000
VERSION     DAEOTL010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28909
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.044"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..1012
                     /gene="hemW"
                     /locus_tag="KRH82_002336"
     CDS             <1..1012
                     /gene="hemW"
                     /locus_tag="KRH82_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HBG8655610.1"
                     /translation="NKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDI
                     DENAEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKN
                     YKDALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYN
                     MYESNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHY
                     IGIGAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRM
                     NKGIKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEF
                     ME"
     gene            1115..2134
                     /gene="hrcA"
                     /locus_tag="KRH82_002337"
     CDS             1115..2134
                     /gene="hrcA"
                     /locus_tag="KRH82_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBG8655611.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            2164..2784
                     /gene="grpE"
                     /locus_tag="KRH82_002338"
     CDS             2164..2784
                     /gene="grpE"
                     /locus_tag="KRH82_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBG8655612.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            2876..4723
                     /gene="dnaK"
                     /locus_tag="KRH82_002339"
     CDS             2876..4723
                     /gene="dnaK"
                     /locus_tag="KRH82_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBG8655613.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            4934..6088
                     /gene="dnaJ"
                     /locus_tag="KRH82_002340"
     CDS             4934..6088
                     /gene="dnaJ"
                     /locus_tag="KRH82_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBG8655614.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            7054..7989
                     /locus_tag="KRH82_002341"
     CDS             7054..7989
                     /locus_tag="KRH82_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBG8655615.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            8025..9398
                     /locus_tag="KRH82_002342"
     CDS             8025..9398
                     /locus_tag="KRH82_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655616.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLANAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(9586..10353)
                     /locus_tag="KRH82_002343"
     CDS             complement(9586..10353)
                     /locus_tag="KRH82_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655617.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(10383..11492)
                     /gene="ugpC"
                     /locus_tag="KRH82_002344"
     CDS             complement(10383..11492)
                     /gene="ugpC"
                     /locus_tag="KRH82_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBG8655618.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            11750..12487
                     /gene="cas6"
                     /locus_tag="KRH82_002345"
     CDS             11750..12487
                     /gene="cas6"
                     /locus_tag="KRH82_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBG8655619.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESVRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREFYYINAYAGTFFLKGD
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            12492..13967
                     /locus_tag="KRH82_002346"
     CDS             12492..13967
                     /locus_tag="KRH82_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655620.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATAKQKEDIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRFDIVKNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     VNTKNLGKKMIDNGNLSNLKELLLDNISFLKQSTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGGEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            13987..15000
                     /locus_tag="KRH82_002347"
     CDS             13987..15000
                     /locus_tag="KRH82_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HBG8655621.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYKGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTSQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            15016..15813
                     /gene="cas5"
                     /locus_tag="KRH82_002348"
     CDS             15016..15813
                     /gene="cas5"
                     /locus_tag="KRH82_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBG8655622.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVALKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            15840..18248
                     /locus_tag="KRH82_002349"
     CDS             15840..18248
                     /locus_tag="KRH82_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBG8655623.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKNILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSTSKVQKEIYDYIE
                     KGILEKEDFNLEDIEDYIKEILYVDFKFNEDVLDYDYIDKLSESMVIYSDYNNGQIED
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            18690..19637
                     /gene="prmA"
                     /locus_tag="KRH82_002350"
     CDS             18690..19637
                     /gene="prmA"
                     /locus_tag="KRH82_002350"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBG8655624.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            19656..20414
                     /locus_tag="KRH82_002351"
     CDS             19656..20414
                     /locus_tag="KRH82_002351"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBG8655625.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            20416..21714
                     /gene="mtaB"
                     /locus_tag="KRH82_002352"
     CDS             20416..21714
                     /gene="mtaB"
                     /locus_tag="KRH82_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBG8655626.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            21757..22107
                     /locus_tag="KRH82_002353"
     CDS             21757..22107
                     /locus_tag="KRH82_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBG8655627.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            22270..22449
                     /locus_tag="KRH82_002354"
     CDS             22270..22449
                     /locus_tag="KRH82_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBG8655628.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            22479..22922
                     /locus_tag="KRH82_002355"
     CDS             22479..22922
                     /locus_tag="KRH82_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBG8655629.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            23033..23530
                     /locus_tag="KRH82_002356"
     CDS             23033..23530
                     /locus_tag="KRH82_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBG8655630.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            23723..24286
                     /gene="raiA"
                     /locus_tag="KRH82_002357"
     CDS             23723..24286
                     /gene="raiA"
                     /locus_tag="KRH82_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBG8655631.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            24499..24735
                     /locus_tag="KRH82_002358"
     CDS             24499..24735
                     /locus_tag="KRH82_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBG8655632.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            24748..26091
                     /gene="yqfD"
                     /locus_tag="KRH82_002359"
     CDS             24748..26091
                     /gene="yqfD"
                     /locus_tag="KRH82_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBG8655633.1"
                     /translation="MISFIRGYYVIVVEGVRLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKESYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            26030..27145
                     /locus_tag="KRH82_002360"
     CDS             26030..27145
                     /locus_tag="KRH82_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBG8655634.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            27202..27663
                     /gene="ybeY"
                     /locus_tag="KRH82_002361"
     CDS             27202..27663
                     /gene="ybeY"
                     /locus_tag="KRH82_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBG8655635.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            27669..28388
                     /locus_tag="KRH82_002362"
     CDS             27669..28388
                     /locus_tag="KRH82_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBG8655636.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            28507..28908
                     /locus_tag="KRH82_002363"
     CDS             28507..28908
                     /locus_tag="KRH82_002363"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBG8655637.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
BASE COUNT        11762 a         2892 c         5201 g         9054 t
ORIGIN      
        1 aaataaagaa tgctgtagtc taaataaaaa tgacaaaata acgagtatat ttgtaggggg
       61 aggtacacct agtatactaa cctctgatga aataagagaa gtatttataa gtataaaaga
      121 aatgtttgat atagatgaga atgcagaaat aactatagag tgtaatcctg ggacattaac
      181 attagaaaaa ttaaaaacta tgaaagagat tggcataaat agacttagta tagggctaca
      241 agctattcaa gaaaagcatt tgaactttat aggaagaata catacttatg aagaatttga
      301 gaaaaactat aaagatgcat taagtgtagg ttttaaaaat attaatgtag atttaatgta
      361 cagtcttcca aatcaaactc tatgtgattg gaaggaaact cttgaaaaag ttgtacactt
      421 aaatccaaca catatatcag cttattccct tatactagaa gaaggaactg aactatacaa
      481 tatgtatgaa agtaataaat ttgaacttat agatgaaaat gtagatatag aaatgtatga
      541 gtatacaata aactacttaa agtcaaaagg atataatcaa tatgaaatat caaactactc
      601 aaaagaaggc tataattgtg agcataatat tttatattgg gaatgtgaac attatatagg
      661 gattggagca ggagcttctg gctatattaa tgagaacaga tacaataatg tagaatcttt
      721 agaagactat catttaagtt tggtaaaaag agaaaaacca atacaagaaa atgaaattct
      781 ttctgagaaa gatatgatag aagaaaagat atttatgggg cttagaatga ataaaggcat
      841 aaaatttgaa gattttaaaa aaaaatttgg aatagatttt agagagaagt ataataagca
      901 aatagaaatg ctattagcta gaaagcttat aaatcagagc tttgaaggta tacaattaac
      961 tcaaaaagga agagaaatat ctaatagtgt atttatagaa tttatggaat aatttttaag
     1021 gtgttgacaa aataaattta taatggtata taatatatat aatcttttta gcactcgaac
     1081 ttagtgagtg ctaacagcta ggaggtataa taatatggaa ttaaatgaaa gaaaattaaa
     1141 tatcctcaaa gctatagtta aagattatat agaaacagct gaagctatag gttctagaac
     1201 aatatctaaa agacatgatt taggtgttag tgctgctacc ataagaaatg aaatggctga
     1261 ccttgaagaa ttagggtatt taattcagcc tcatacttct gcgggtagag ttccatctga
     1321 aaaaggctat aagttatatg taaactctct tatgagtaaa agcgaattgg atgataatga
     1381 taagattctt attgaacaat gtatgaatca caatataaat catataaaag aattgattca
     1441 tgaaacttct aagctattat cgcaactaac aaactataca actgtagcag ttactaagag
     1501 tttaataaat caaagtgtta taaagcacat acagttggtt gctatgaatg acaataatat
     1561 tttacttata gttgtaacag ataaagggga cttaaaaaaa gctaacctta caactaatgt
     1621 atatttagat caatctaagt taaatttgat ttctgataat cttacaagga agctcttagg
     1681 taaaagtata acagatttgg atgataatct aattgctttt attaaatacg aaataagtga
     1741 gtattctggg cttatagatg agcttttaaa tgctttgaac tcaaatatga aagaagaaga
     1801 tttttctcta tcattaaatg gagctactaa catatttagt tatccagaat ttaatgatgt
     1861 attaaaagca aagtcatttt taaatatgtt ggaaaaaaag gaaacaatag ctgacataat
     1921 taaatcaaag ggaatacaaa aagacaatct aaatataata attggtagtg ataatgattg
     1981 tgaactggca caggattgta gtatagttac agcaacttat aatgtagata gagacttggt
     2041 tgggcgaata agctttatag gccctaccag aatggattat gctagaattt actctataat
     2101 aaattatatg agtttattaa ttaatagaaa gtaaagaaat tttaaattgc gaggtgtaaa
     2161 gtcttggata aaaaaaatga gcaacaggaa gtaagagaag aaaatgatac ttctattaac
     2221 caagaatcgg aaactcaagt agagttagaa gaggaagttg ttaatgaaga atgtgaaaca
     2281 tcaagtgaaa aaactgatga aaaagaagtt gatgatgaaa atgtaacaga tataaattct
     2341 aagttagcag aaaaaaaatt gcaggatgag ttggatgaat taaatgataa atatcaaaga
     2401 cttcaagccg aatatgcaaa ctacagaaga agaactcaac aagagaaaga gacaataggc
     2461 gtatttgcaa atgaaaaaat aataactgaa ttgataccag ttatagatag tatggaaaga
     2521 gccttagatg catgtgaaga taaggaagat actatgtata agggtataag ccttgtacat
     2581 aaacaattaa tagacacttt agtaaaattt ggagtagaag aaatagaagc agaatctaag
     2641 gaatttgacc ctaatctaca tctagcagtt atgcaagaaa gtgtagatgg agttgaagca
     2701 aatcaaatag taatggtact tcaaaaagga tataagctag gaactaaagt tgtaagacct
     2761 tcaatggtta aagtttcttg ctaagtataa attaaaggtt aaattattta acctaatata
     2821 aaatattaaa ataagtaaaa cttaattata taattactcg aggaggattt tagtcatggg
     2881 aaaaataata ggaatagatt taggaacaac aaattcatgt gttgcagtgt tagaaggtgg
     2941 agaagcacaa ataatagcaa atagtgaagg tatgagaact actccatcag tagtagcatt
     3001 tacaaaagat ggtgaaagaa tagttggaga acctgcaaaa agacaagcag ttacaaatgc
     3061 agataaaaca ataacttcta taaaaactca tatgggaact gattataaag taaatataga
     3121 tggaaaatca tatactccac aagaaatatc agcaataata ttacaaaaat taaaatcaga
     3181 tgcagaaagt tacttaggac aaacagtaac agaagcagtt ataacagtac cagcttactt
     3241 tacagatgct caaagacaag caactaaaga tgctggtaga atagcagggc ttgatgttaa
     3301 gagaataata aatgagccaa cagcagcagc tcttgcttat ggtatggata aattagacca
     3361 agaaaagaaa atattagtat ttgacttagg tggaggaact tttgacgtat ctatacttga
     3421 aataggagat ggaacttttg aagttttagc tacagctggt aacaatagat taggtggaga
     3481 tgactttgac caaatagtaa tagattattt agcagaggaa tttaaaaaag ctgaaggtgt
     3541 agatttaaga aatgataaaa tggctcttca aagattaaaa gaagcagcag aaaaggctaa
     3601 gaaagaatta tcatcaacaa tgagttcaaa cataaactta cctttcataa ctgctacagc
     3661 agaaggacca aaacacttaa atatagattt atcaagagct aaatttgaag aattaactag
     3721 aggtttagtt gaaaaaacta tggaaccaac taagacagct ttacaagatg caggactttc
     3781 tacaggtgat atagatgatg tattattagt aggtggttct acaagaatac cagcagtaca
     3841 agaagctgtt aagaagttta taggaaaaga acctcataaa ggtataaacc cagatgagtg
     3901 tgttgcagca ggtgcttcta tacaagctgg agttttagca ggggatgtta aagacttatt
     3961 attactagat gttactccat tatctcttgg tatagaaact atgggtaatg taatgactaa
     4021 gataatagaa agaaatacta caataccaac taagaagtct caaatattct caactgctgc
     4081 tgataaccaa acagctgttg atatacatgt tcttcaaggt gaaagaagta tggcttatga
     4141 caatacaact ttaggaagat tccaattaac agatatacca ccagcacaaa gaggaatacc
     4201 tcaaatagaa gttacttttg atatagatgc aaatggtata gttaatgttt cagctaaaga
     4261 tttaggtaca ggaaaagagc aaaaaataac tataacatca aacactaatt tatcagaagc
     4321 agaaatagag caaaagataa aagaagcaga aatgaatgca gaagctgaca aacaaaagaa
     4381 agaaaaaata gaagcattca atcaagctga atctactata tatcaaactg aaaaaacttt
     4441 aaatgaactt ggagataaaa taagttcagg tgaaaaagag gatatagaaa aagctatagc
     4501 agatttaaaa gctgtaaaag ataatcaaga tgctacagca gaagaactta agaaagctac
     4561 agatgaagta atgactaagt tccaaaaagt atctcaagaa atgtaccaaa aagcagctca
     4621 agaacaacaa gcggcacaag gtgcagaaca agcacaagac aatggaccta aagatgacaa
     4681 tgtagtagat gctgacttta aagaagtaga tgaagataaa taagctatat aatatgtaac
     4741 actaaatgat aattggaaca tatatgattt gtgaaaatca tatagatgtt aaagatatat
     4801 ggacaatata catcataaag aatataatat atcatagatt atataactta aagtagaata
     4861 taagaattaa tgatagcttg tagtttatta ttctacaagc tatcgttttg taaaatgaag
     4921 gtggtgtcaa tttttgagta caaaaaggga ttattatgaa gtcttaggta tcagtaaagg
     4981 tgcagaagct caagagataa aaaaagctta tagaaaatta gcaatgaagt accatccaga
     5041 tagaaatcct ggagataaag aggcggaaga aaaatttaaa gagataaatg aagcttatga
     5101 agttctatct gatgatacaa agagaaaaac ttatgaccag tttggacatg atgggctaaa
     5161 tggtcaaggc ggttttggtg gtcaaggagg atttggcggt caaggctttg gtggttttga
     5221 agatatgttc ggagatatat ttggtgacat gtttggagga agcttcggag gtggaagagc
     5281 aagaagaaga ggacctcaac gtggtgcaga tataagacag agtgttacta tatcttttga
     5341 agaagctgca tttggtaaaa agatgtctat aaaagtaaat agaagtgaag agtgtgaaga
     5401 atgtaatgga actggagcaa aaccaggaac atcaaagaaa acttgttcaa cttgtaatgg
     5461 aactggtcaa gttagaactg ttcaaagaac tccatttggt aatatagcaa gttcaagacc
     5521 atgtagtgct tgtaatggaa ctggagaagt gattgaatct ccatgtagta aatgtcatgg
     5581 aactggaaat acaagaaaag ttaagactat agaagtagat atacctgctg gtatagatga
     5641 tggtcaaatg ataaaacttt ctggtcaagg tgaagtagga gaaaaaggtg ctccaagagg
     5701 agacctatat attgtagtta atgttaagtc acatccacta tttactagag atggaaatga
     5761 tatttatttt gaaatgccaa ttacatttgt tcaagcaact ttaggtgatg agatagaagt
     5821 acctactttg gatggaaaag ttaaatatag tgtgccagag gggacacaaa ctggaactgt
     5881 atttagactt aaagagaaag gaatccctag aattagaggt aattcaagag gagaccaata
     5941 tgttaaggtt gtagttgaaa ttcctaaaaa attaaacgat aagcaaaaag aactattgag
     6001 agaatttgcg aaggagtgtg ggtcgaacgt ccacgaaaag aagaaaacct tcggacaaaa
     6061 gatagaagat atgtttaaga aaaagtagtt aaagtagcca atatataatc atatttttaa
     6121 aatcttagtt atttataaga ttgtcaaagg agatattatg atttttatat tggctatttt
     6181 tgtataaaaa ataaatgtgc ataaaataaa actgaatata aataattttc tgaaaaatac
     6241 ttgtcctaaa atatataatg tgctataata taatcaaata aaagaaaggg gtgattccag
     6301 tgggaacgga tgtggcactg ccaaatgatg aagaaaactt tattgtaata tacaaaataa
     6361 aattagatac ttttagtgct agattaagta ctggaaaaac tcatgagctg ggataattat
     6421 tgtaattacc tagactcaaa cttttagtag taaaatagta atattatata gacaaggtat
     6481 ctaattttta aatcttttgt atgaattaaa atttttataa agggtatatc tgattagaat
     6541 gtaattaggg aaacctagtt gtgaattact tttagtatat acatgtgtaa agaaatatgt
     6601 atatggtatt ggttattgtg ctagatgtgt atgtaaagaa atatgtgtct agttgggtat
     6661 atgtaaagaa atatacttat aatctatgaa aaatttttag tataaattgc taaaacattg
     6721 agattgtttt ttatagaaag ttagtttata ccaactaaaa atgtgcttaa gatttgtttg
     6781 atgtttaatt ataaataagg ttgtagataa aaaaataagt aaagacaaag gtttaaaata
     6841 cttgctttaa atatagtttg ttttgaacac ttgccaaatt aaaataatta ataaaataga
     6901 catcttctca tagtaaaata tactgtgaga ggatgttttt gctttgttca taaactttta
     6961 tgaaaaattt gcatagtgtc acattttaat atactatata tataataaaa tatagataaa
     7021 attaaatgat tcaaaagaga aaggtgaaaa gagatgtatt atataggtgt agacatagga
     7081 ggaacaggta tacaagcagg agtagttgat aactatggga aaataatttt taggtcagag
     7141 tgtaaaacag taattgaaaa aggatttgaa ggaatactta atgacataaa aataatgatt
     7201 tataagttgt tggaagataa taaacttact atgagtgaca taaaatctat tggatttggt
     7261 gttccaggtt ttataaataa agaaggatta gtaacttgtg taaatttaaa atggaataaa
     7321 aaagctttta ataaagagtt aaaaagaaga tttccagatg ttgaaattca tggagaaaat
     7381 gatgcaacag tagcagcact tggagaagca aagtttggaa gtatgaaagg tgctaatgtt
     7441 ggagtattat atactttagg aactggtgta ggtggaggaa tagtaattaa tcaaaaagtc
     7501 ttttctggag cacatggatt gggttcagaa ataggtcatc aaattatagg agaaaactat
     7561 tttaattgta attgtggaaa taatggttgt gtagaaactt tttgttcagc aactgcaatt
     7621 ataaagtatt ctcaaaaact gatagaagaa ggagaaaaga gtaggatttt agatttggca
     7681 gagggaaatt tagaaaatgt aaatgcaaag atggtgtttg atgcatatag agaaaatgat
     7741 ttagtggcaa ttaaagtaat aaatagattt aaagagtatt tagcaaaaac ttttgcaaac
     7801 acaataaatt ctttagaccc agaaattata tctataggag gaggcatttc taaatctagc
     7861 gatataatac ttgatggaat agaagatttg gtaagaaaat ttgtattata caaaacagaa
     7921 gatatagcta caattacatg tgcaacttta ggttcagacg caggaattat aggagcagct
     7981 tttttataat gtaaatgaac tgcttattgg aggcgtgatg atatatgggt aaaacaaatg
     8041 ctagaagaac gctttttttg atagcaatag gttcaggaac tatgctgaat cctcttaatt
     8101 cttctatgat ttcacttgct ttacatagta tacaaaatga ttttcatatt agttttacaa
     8161 ctgtatcttg gattgtttca gcattttacc tagctaatgc tattgcacaa ccagtttcag
     8221 gtaagatagg agatttaata ggtagaaagg tcttattttt gagtggtttg atgcttgtaa
     8281 ttttatcagc atccatagta ccacttgttc aatcattctt tatattgatt tttataagag
     8341 taattcaagc aattggaaca agtaccctat atccatctgg agttgctctt atacaaaata
     8401 atataaaaga aagacaatct tctgcattag cagttctaac catttttgct tcaactacag
     8461 caggattagg tccgacactt ggaggattat tgttggactt aggaggatgg catgctatat
     8521 ttcttgtaaa tatacctgtt gttttggttt ctatatgcct agggtatttt ttattcccaa
     8581 aagaagtaaa agaaaagaaa tctataaaag aaactttaaa aaatgttttg tcaagattag
     8641 atattattgg catacttcta ttttcaattg caatgatttt tatattacta tttttgctat
     8701 ctatgaagga atcttttaac ttagaacaac ttgtatttgg tataatactg atgtgtcttt
     8761 ttatttggca tgaattgaga acaaaattgc catttataga tattaagctt tttgtaagta
     8821 atcctaaatt gtcaaaagtt tacttgcaat ttattatatt aaatttcttt aattatattt
     8881 tgttttttgg tcttcctagt tattttcaag atgccttaca ttatagtgca aagtcgactg
     8941 gattatttat gctatttatg tctggtatag gtatatttat atctccatta actggaaaat
     9001 ggatagataa atctggaact agatttcctc ttgttacatc atcaatcttt atgtttatta
     9061 gtgcagtact tctttcagta gtttttatcc atatacctgt aataggaaag ggtattatat
     9121 tatcattagc aggtattagt tatggagttg gtaatgtagc cctgcaatcc tctatgtttg
     9181 aagaaagtcc tcgtgacagt atagggacag cttctggtct gtttcaaact agtcgttatt
     9241 taggttctat tttagcaact gttttacttg gaatggtatt tgaagtaaat ataacatcag
     9301 aacaatttca gatattaggt tatgttatgg tggtcttagg tacaataagt tttttattaa
     9361 attttatatt aaagaaagaa ttaagaaaag tagaatagtg gatttatgga tttaataagt
     9421 ctaataactg ataagtttaa aaatattgtt tgtaaaacat aactggtttg atatttatta
     9481 attctaagtt ttgaagcata gagtactcga taagtataca atattttgaa ttaaaattaa
     9541 gcagaaattt gaactagtct ttcaaatctc tgcttaattt agtggttaaa tttttttata
     9601 gagaaaataa gatttgacac ttagataaaa aatcattgca ttttcaaaat tctttaaatc
     9661 aaacccaagt atctcattaa tcttttccaa tctatatact agcgtgtttc tatgtaaaaa
     9721 catactagta gatgtcttag aaatatttaa atcattattt ataaatttta ttcctgtata
     9781 tagaagttct tcatcaatag atttaatctt attaaaatct attaatttat tgagtatatt
     9841 atcctcatta attaaatcta aagttttata tctaataagg tcaaacaaat ttaaaaactt
     9901 attttcagcg ttgtctttta taatatgagg tagtaaatca gaacataact gtaatctaaa
     9961 atcaaaatca gctttactat ctaatttacc aagataaaaa atataagtac tttgataagt
    10021 ttcagtttca attatatttt gtgtagttac attaatatct aagttatatt tagaatttac
    10081 tataaaaaaa ccattgtgtt gtattatatt tatatcttca aataaattat aaaaaatatt
    10141 ttttagatat tcaaagtcta tatgagattg gtaaattaaa taaaagttgc cttttaaatt
    10201 atcaagatta tttttatcta gaaaatcaat aacataaata gcattattga aagtaactaa
    10261 atggctacta gcatctaact tttggttttc atatggatag atatttattt ttttattaag
    10321 ctgtctttct aaaaaatctt ttaactcttc cataaagtct ccttaaaaat aagattatat
    10381 tcttatctta tagctaaagt agtttctttg tcaaatatgt gtactctact attgtcaact
    10441 gaaagtgtta agtcatcacc aacattaatt ctgtttttac tgtcaaatct aattgttatc
    10501 gtattttctc ctagttttaa gtgagcataa gtttctgctc ccataagttc ttttatttca
    10561 attcttgatt taaaacaagt atctggatta gatttaataa aagtatcttc tacatgaata
    10621 tcttctggtc tgatacctat aacaacttca ttattaatat aattgtcttt tattaaatca
    10681 tagtgttttt ctttattcaa tttaagctta atatgttcat tttgtgcata aatttcatca
    10741 ttttcttcta ttaatattac atcaataaaa ttcatctgtg gtgctccaat aaatcctgca
    10801 acaaatatat tagctggata atcgtataca tcttgtggag ttgcaatctg ctgaactact
    10861 ccatccttca ttactacgat tctatcagcc atagtcatag cttcaacttg gtcgtgtgtt
    10921 acatagataa atgtagttcc aagctgttgg tgtagcttag ttatctctgt tctcatagca
    10981 gttctaagtt ttgcatctaa gttggataga ggttcatcca ttaagaatac cttaggattt
    11041 ctaactattg cacgtcctaa ggcaaccctt tgtctttgtc ctccagataa tgttttaggt
    11101 tttttattta aaagaggtag taagtctaat attttagcag cttctttaac ttttttgtct
    11161 atttcatctt taggcaattt tctaagttta agtgcaaatg ccatgttttc gtaaacagat
    11221 aagtggggat ataaagcata gttttgaaaa accatagcta tatctctatc ttttggttct
    11281 atatcattga caagtttatc tccaatgtat agttctcctt cagagatttc ttcaagacca
    11341 gcaatcattc taagtgtagt cgatttacca caaccagatg gtcctactaa aacgataaat
    11401 tctttatctt taatgtctat atttatattt tttactgcat taaatccatt tgagtaaagt
    11461 tttgatatat tttttaaaat tacttctgac ataatatcct ccttgatatt taaattttaa
    11521 ttatatagta tcaaattttt ttattatatt aaatgtgtaa aatgactaaa tgtatttgtt
    11581 taatatgtat atttagtttt tagcaaagaa taaaactaac agtaaaatat atttaaaaaa
    11641 ttaaaaaaca aaattaaatg tattatcaaa aaatcatttt atgatatgtt ttatttttat
    11701 attacaaata gagaataatg aattatacta gaaagtagga ggtgaaaata tgagcagaat
    11761 ttcaattttt atggaatcat gtaatggcaa atttccaaat gaaaattcaa tgttgtcggt
    11821 ttcctttata aaaaatattt taaatgcaga aaataaagat tttgctaaaa atatatttaa
    11881 ctatggggaa gaaagaaaaa acaataagca aataaaggat ataaatacag ccatttacat
    11941 accaaatctt ataagaagca aaaatgagtt acttgttgat ggagatataa tattcaatat
    12001 aagtttttat aattattcta tgttcagtaa attatacaat ggaattttaa aagtaaagga
    12061 gctagaatat aaaggttata gatttaaaat aaaaaatata aaaatacata aagaacacga
    12121 gataaaagaa aatggtgtta tatttaaaac tatgtctcct ataatagtaa agaataaaga
    12181 aggtaaatat ttagatgtag aagattcaaa ttatatagaa tgtttaaact atatagctaa
    12241 tctaactctg gagagtgtaa gaggtagtgg gcttagaaag ccattggaat ttatacctct
    12301 taacttcaaa aaaagagtgt taaaagaaaa gattcgtgga tttaaagtga gagaatttta
    12361 ctatataaat gcttatgcag gaacattttt tttaaaagga gatatggaag atttaaatgc
    12421 actgtataaa atgggaattg gatatagaag gacggaaaat gcaggaatgg ttgatatatt
    12481 aaagtagcga ggtgagagaa ataaaagcta aattttatag atcaggtgat attgtaagag
    12541 atattggcat tgtttacttt tatgaattac taatggattt aaaaaacgaa ctagaaaaaa
    12601 atgattataa gctaaaattt acttgtgagc taaatagaaa ttatttatct ttagaatctg
    12661 cagaatatat agaccctaag tatatatctg attatatatt agaaaatcaa ctttttaagg
    12721 tatttaaaaa tgggaaaaag gaaaccttag aaaaaatatt tagtaatata gataatttaa
    12781 cgtatgtaaa ttttattgaa gaattggata aatcttctgc aactgctaaa caaaaggaag
    12841 atattaaaaa agattttaaa aacaggaggt ttccatatgt tagaaatagt ggtaagtatg
    12901 gactaaacac gagtttagaa aatatggaaa caaatgtaaa aagaatagta gatactgtaa
    12961 ttaaatcaaa tatagagata gatgaaatag ataaacttga tttgacacaa tatgaagaaa
    13021 aagatagtgt atgtaatgtt tgtaatataa ataaaacaac aaaactagat attgatttaa
    13081 gagagcgaaa ggactctaag tataactttt tatttagagg tgcagaaaaa tcaggcttta
    13141 aaagaagtgg acaagttgaa agtaatattt gttttgagtg tgaatttttc aacttaatgt
    13201 gtcttttata tataaattta aaaagaccaa tggtttttgc atatacgaat gatttaagag
    13261 aattagcatt tttaaatcat aagataatgc ttaaaagaaa aatgtattca gataaatcat
    13321 tttataaaaa acttttgcat gaaaaaataa gttcaattag actatataga tttgatattg
    13381 ttaagaataa aggtataatt ctaaagtttg actctattat agagtataaa gaattattaa
    13441 aaaaaattga acttatagat attatagata attataattt ctcaagggag ccagtaaaca
    13501 ctaaaaattt aggtaaaaaa atgattgata atgggaattt atcaaattta aaagaattat
    13561 tacttgataa tataagtttt ttaaagcaat caactggaac ttctcgagaa atggattttg
    13621 tatctagctc atataatatc ggtttatata taaaattgtg ttggattgta gatggagggg
    13681 aggagtataa aatgaaaaac tatatggaaa gtaatttaat atattcaaga gtaggtaaag
    13741 acttatttaa taaaatgaca gatgaatcca gaagaaaaaa tttttctatg aaagtgattc
    13801 aactacttaa gtctaatgat agaactcagc tatttcaaac tataatgcat gtgttagttt
    13861 ctaatggaat cttaatagga gaagggtttg tagaaggtct aatgcagagt tctgaattag
    13921 aattaaatac gaatgtaggt ctatttattc aagaaatcat gaaataaaaa agggggaaaa
    13981 tttaaaatga atgaaaaaag agtaaaagga gtaacattaa ctatactgac agaaagccca
    14041 gttccacttt catatgacca agggtatgga aattatacac caataaaaaa agaacaatat
    14101 agagaaaaaa tacatgcaaa aactagtata gccacaataa catatgattt aagaagaatg
    14161 ctccaccaag aatatggttg gaatttaagt aatattgttt ttggaaaaaa aggaaatata
    14221 tatccatcta ttaagaaaaa tgtaggatgt gtagatgaaa atggattaga gactgatgta
    14281 tttggttatt tgataccact taaagataaa ggttctataa gtaaagcttc tccacttaga
    14341 ataatacctt ttaggtcatt aaatccatat aaaggttcaa cacagctaat aacaaataga
    14401 ggttttttaa gtagtgaatt tggtagaaaa tattatgatg agaaggaaga aaatgaagta
    14461 cctagagatg aaaactttcc aacatcacaa gcattagcaa tagaagagac tttatcagat
    14521 tactacgttt atacaataac attggagctt gatagaatag gagtagtaga agtagaagat
    14581 ggaaagttac ttttaccaga agaaagaaaa tttatgagta aggagttaag agaaaaagca
    14641 gtaaaagata tattagatgc aattactgtg tttacaagaa acataaaaca ttcatcagta
    14701 ctattaaaac cacttgcagt aatgggtgga gcttttgata aagttgtacc gtttttttgg
    14761 gatgatgtag attataatgc tgatagtggt gagataaatt tagagggagt tatagaaact
    14821 atagaaagtt atagtcttaa agaaagtaat acaatacttg ctatcaatga cagattaaaa
    14881 atttctaata aaaaggaatt aaataagttt aatttaagta aataccctgt aaaagagatt
    14941 aaaaatctag cagatagatt ggaaattgga gaagataata tgtggtattt aaaagagtag
    15001 gaggtttttt gaattatgaa agtattacaa tgtaaactta agcaaccaac tgctcactat
    15061 agagacccaa aagtatttca aaatgaatat ataagtactt taaatttacc atctaagacc
    15121 acaataatgg gaatgataac gtatttatgt gatagaagat taaactctga tatagatata
    15181 ggaataattg gaacacatca tcatagagaa ctagaatttt caagaggaga gaacattgat
    15241 ttttggaatg aatatacaaa tatgagaaaa ggcaaagata aagaaaagtt tttgcttcaa
    15301 ggaaactact atgattacta taaagaacat aaagctcaaa atagcatatt aaactatgaa
    15361 gttcttaaag aagtagaatt gactatattt atttcttgca aggatgatga agaacttgaa
    15421 tttattagaa aaaagcttga aagtccatgt aaatatgcaa atttaggaag aaaagaagat
    15481 tttgtaatac caagtgaaaa agggtgtttt gtaaaagaag ttgcgttaaa agaggttata
    15541 cctatgaata ctcgtgatgc tataaaagaa aatataaaat taaagaatac atatgtaaga
    15601 gttgacttaa gagataaaga gaatgtcgag actataataa atcaaggtgt attgattgca
    15661 ttgcctcata aatataaaga tttagaagca aatagagatg atagagttta tgagttttgc
    15721 cattatatat atgttgataa tgatggtata tatcctaaaa atattaaggt aaatgtatgt
    15781 attgatacaa aagaagtttt tacatggctt taaattattt tgaaagatag gtgtttatca
    15841 tgaaaaatat catgcaaaaa gaaatattag ctaagtcata caatttaaga actaatcaac
    15901 aagaacaaac attagttgaa catattaagg atttatttga agtattagaa tctatattag
    15961 aactaaatct atattcagat aaagatgtag agatactaaa aatatgttgt gctttgcacg
    16021 atttaggaaa aattaattca attatgcaac aaaaaatgga gattaataat aaaatatcgt
    16081 atagttgttc agaagaagag aggaaaaagt tagagtctga caaaaaatct ttaaaaaaga
    16141 tagcaagaca caatatattt tctggagcat ttttaaaaaa tatactagaa aaaatgaact
    16201 tgtcagaaga agataagtta tatatatata aaagtataat gttacatcat ggaaactatg
    16261 aagattatat gaggttaagt actagtaaag ttcaaaaaga aatttatgat tatattgaaa
    16321 aaggtatttt agaaaaagaa gattttaatt tggaagatat agaagattat ataaaggaga
    16381 ttttatatgt agattttaaa tttaatgaag atgtattgga ttatgattac atagataaat
    16441 taagtgaaag tatggttata tacagtgatt ataacaatgg tcaaatagaa gattcagttt
    16501 taaattatag aaagtttaag tatattttat ataaagggat gctgaactta atagaccata
    16561 gtgcatcaag tagacagaaa ggtataaaat tttataacga ttttactgat gaagaaattg
    16621 ataatatgat tttaaatgag atatataaga gtcagggtaa tttagaaaaa aataatatag
    16681 agttcaatac tatacaaaaa aggttgagag aactttctgg aagaaatgtt ctgactgttg
    16741 catttacagg ttcaggaaaa acagctgcag attatagaaa gacttttaaa agaaaattct
    16801 ttttagtgcc aaataaaata tcagcagaaa gtttttatag aaaaaatatt tttcaaaata
    16861 aaaatgattt agatacaaga agtagtaatg attacattgg attacttcat ggagatataa
    16921 acttatattc agagaatgaa gataatggag aacatgattt tgtattgaca ttaagggata
    16981 tagatttgag tataaacttt tgcaaacctt gtgtaattgc aacagttgat cagttattac
    17041 ttagtatgtt taaatttccg ggatatgaaa aaatattcgc agccgtaaaa aatgcatcta
    17101 taactgttga tgaagtacat ttattggaac caaagatgtt tttgattttg atatatttta
    17161 tgcagtttgc atgcaagtac ttagatgttg attttcactt aatgacagct acacttccaa
    17221 aatcatataa agagcaaatg ataaacaagg gaattatttt tcaagaagaa agtaatgaaa
    17281 atgttactga taaaggagaa atagttttta ttgagagcaa caaggaagaa gagatttgtg
    17341 aaggtaaaga tgtaaaggtt tcttttataa aggaaaaaga aatcaagtca atagttgaag
    17401 atgctttaga aaataaacaa aaaattctta taataaagaa tactattgat tcagtcaata
    17461 gaacatatga gtttttaaaa gaaaatttat ctgataagta tggtggtgta gatatagatg
    17521 ttttacatag tagatttaag ttcaaagata aaaaagagaa atatagtaaa atattaaatg
    17581 gagagggtga tatttggata tcaactcaat cagtagaaat atccttggat ttggatttca
    17641 atataataat aagtgattta gcaactatgg atagcttaat acaaagaatg ggtagatgca
    17701 atagaaataa taaatatgaa tatggaaact tttatattct acctagtgaa gataaaattt
    17761 atgacaacaa acttaagagc acaactaaaa acatcttaaa ggacatatta aaaactaact
    17821 ctatttttac aatgggaatt agaaaaacta ttttggatga ttactatgat aatagtgtag
    17881 tcaaaaaata ttttgaagag aattttataa gttgtgataa agaaattaag aatatttatg
    17941 gtgtaaataa agaaattttt gatggattgg atttaatttt taattttgaa ccttacaaaa
    18001 atattgttga tagtaagaag gaagcagcta aaatttttag agatgttgat gttagttaca
    18061 aaattattct ggaagaagat ttttataagg aagatagaga gttacaacaa gattcgattc
    18121 aagtatcagg gtttatattt aatagattat attattatgg gttaataagc aaagtagaag
    18181 gatacatggt actaaaatct agtagtaagt ttgagtataa tagtactgta ggcttaattt
    18241 tgaagtgagc atatgtttaa atataatata cctttagaca ttgaaaatac aaaaagtact
    18301 actgtaagct cactgtaaaa actatttttt taaaaggaaa aataagttgt gagatagagt
    18361 gtttacaagt gtatatagat aataaatttg aggtttaaga ttaactaagt gggtttcagg
    18421 tacatcgcga aaataattat aagttggaga ttttgtatgt ttaagattaa ctaagtggat
    18481 ttcaaatatt gatatagtag atataataga agttttatta ttaggtttaa aattaactaa
    18541 tcggattttt aaatattctg actattatat aaggatatta ttagcttgaa tttaaaacca
    18601 ataatataaa acaacaaaat attatattta tgatataata aaagttatgg aaaaacagga
    18661 atattactat agagaagaga ggtaaactta tgaataattg gatagaagta actataaaaa
    18721 caacaacaga agcagttgaa cctataacga atatactata tgaacaagga gctggaggag
    18781 ctgtaataga agacccaaaa gactttttat tccaaaagaa aaatgaacta gactgggatt
    18841 atgttgaaga agaagtattt aaaaagaatg aagaagatga tgttcttata aaaacttatg
    18901 tttctgaaga aaaaaatgtg atggaatttg tcgaaataat aaagcaaaaa gttttaggat
    18961 taaaagattt tggtatagat ataggtgaag gaagtgtatc attggaccaa gtaaatgaag
    19021 ctgattgggc aaatgcatgg aaagcatact acaaaccaac aaaagtggga caaagggtag
    19081 tagtaaaacc tacatgggaa gattatgcta tgcaagaggg ggatttaatc atagagcttg
    19141 accctggaat ggcatttggt acagggacac atgagactac tagtatgtgc attagagaat
    19201 tagaaaagta tgtgaataaa gattctaaag tatttgatat tggatgtggt agtggaatcc
    19261 ttgcaatagc agcagccaaa ttaggagcaa aagaagttgt agctgtagat ttagatgaag
    19321 tggctgtaaa agttgcaaaa gaaaatgttc ttgaaaataa agttgaaaaa agtgtatctg
    19381 taatgcatgg taatttaacc gatgtaataa aagataaagc ggatgtaata gttgcaaata
    19441 taatagctga tataataaag atacttgcaa aagatgttca aaactttatg aaagaagatg
    19501 ctatattcat atcttcaggt ataattttgg ataaagtaga agaagttaaa gaaagcttaa
    19561 ttgaaaatgg atttgaaata gttgaagttc aaaaattagg tgaatggtca gcaatagttt
    19621 ctaagcttaa aaaataaggg atatggtgac gtataatgga tagatttttt gttgaaaaaa
    19681 ataatataaa tctacaagat aaaacttgca ctatagaagg tgaagatgta aaacatattt
    19741 caaaagtttt aagatgcaaa ttaggtgaga aacttgaaat atgtgacaag aataataatg
    19801 agtatatttg tgagataatg aatatagata agagtatagt taatttagag attttagaaa
    19861 aagttgatat aaatagagaa tcagaactta aagtaaggct ataccaggga cttccaaaag
    19921 ctccaaaaat ggaaatgata cttcaaaaat taactgaagt gggtgtagaa gaaataatat
    19981 tagttcaaac taagagaagt gttgttaaag ttgatgacaa aaaagaagat aaaaaatttg
    20041 aacgttggga aagaataatt tatgaagcag caaagcaaag caaaagaggt aagataccaa
    20101 aattaagagg tgttttaagt tttaaagaag ctttagaaga tatgaaaaaa aataatgtaa
    20161 atatttgccc ttatgaaaat gaaagaacag tttcaataaa acatgcacta aaaaaatgtg
    20221 attctaatat agatagtgtt ggaattttta taggtccaga aggtggattt tctgaagaag
    20281 aaatagaaca aatacaaaaa aataattgta atgttgtatc attggggcct agaatattaa
    20341 gaactgagac agcttctgtt gtagcatcaa caatagcttt gtatgaacta agtgatttag
    20401 gaggagaaaa ataaattgaa aaaagtagct ttttatacac ttgggtgtaa agttaatcaa
    20461 tatgaaacag aagctatgct agaactattt gagaaagatg gttatgaaca agtcaatagt
    20521 gaagagtatg ctgatgttta tgttataaat acatgtacag ttactcatat gagtgataga
    20581 aaatctcgtc aatatataag acgagttaaa aagaagaatc cagatgcaat aatagccgtt
    20641 gtaggatgtt attctcaggt atctccggaa gaaattttgg atatagaaga agtaaattta
    20701 gtcatgggta caaatgatag aagaaagatt gttgaagaaa ttaaaaagat aaattcaagt
    20761 aagaaagtta gtacagttga cgacataatg aaagttaaag cttttgaaga aatagaaatc
    20821 agccaaacta atggaaagac tagagcattt atgaaaatac aagatggatg tgacagattt
    20881 tgtacttatt gtatcattcc ttatgcccga ggacgcgtta gaagtagaga tattgatagt
    20941 atagtcgatg aagtgaaaaa attggctaat aatggctata aagaggttgt attaacagga
    21001 atacatgttg cctcttatgg aaaagattta aaggataggg atattaaact tcttgatgta
    21061 ataaaacaaa taaaccagat agaaaaaata gaaagaatta ggcttagttc tgttgaacca
    21121 attttattta cagatgaatt tgtaaatgaa gttttaaaga tggataaagt ttgtcctcat
    21181 taccatttat cacttcaaag tggatgtgat gaaactctaa aaagaatgaa tagacgatac
    21241 acaactttag agtacaaaac tattgtagat agattgagaa gtaaaatgcc agatgtggca
    21301 ataactacag atgtaatagt aggttttcct ggagagacaa atgaagagtt taaaaaaacg
    21361 tacgagtttt taaaagaaat agagctttca caaatgcata tttttaaata ttcaccaaga
    21421 aaaggaactc cagctgcaac tatggaaaat caagttgacc ctcaaatgaa acactttaga
    21481 agtgaacaac ttttaaattt aagtaaagta aattttaata aatttgcaac taaatttatc
    21541 ggccgtgagt tggatgtttt gtttgaacaa aatatagaag gcaataaata tgagggatta
    21601 acttcaaatt atataagagt tgttgttgaa agtgacaaaa atatacaagg tcagatatta
    21661 aaagtgaaaa taaatgatgt aaaagatgaa tatgtagaag gaattttgct ataacatgta
    21721 gaaattataa tatttataag ataggaggtg gaaagaatgg attgtatttt ttgtaaaata
    21781 gcgaacggag aaataccttc aactaaagtt tatgaagatg atagagtctt agcttttaat
    21841 gacttgaacc cagttgctcc atatcatata ttagttgtac ctaaaaaaca ttatgatagt
    21901 ttaattgata ttcctgataa agagatggac attgtgtcac atattcatgt tgttattaat
    21961 aaaatagcta aagagaaagg ttttgaccaa actggattca gagtcataaa taattgtgga
    22021 agtgatggag ggcaagaagt taaacatttg cactatcata ttttagctgg taaaaagctt
    22081 cctaattacg aagcgggaca aaactaaact aaattattga aaaattgagt tccttcttga
    22141 taaaaatact tgataaaagt aaaaatttag tttataataa acaaagtgtt aggttgtaat
    22201 gcatattatg caaaaagaac atagttacag tcccagcata attgcgctat tggagggagg
    22261 gaaaaagaaa tgtcagaagt aagagttaga gagaatgaaa cattagacag cgctttaaga
    22321 agattcaagc gtcaatgtgc aatgtctggc atcatgtcag aagtgagaaa aagagagcac
    22381 tatgataagc caagcgttaa gcgtaagaaa aaagctgaag cagcaagaag aaaaaacgct
    22441 aagaaatagt agtaaataag aataaagagg tgaaggggat gtcccttaag caaaagttac
    22501 aagaggattt gaaatcttcg atgaaaaaca aagatacagt gagaaaatct gtagtaactt
    22561 taataagagc ttctataaag cagtatgagg ttgataatag ggtcgagctt gatgaagatg
    22621 gaattatcga tgtaatagca aaacaattaa agcaacgtag agatgcatta gttgaatttg
    22681 aaaaagctgg aagagaagac ttaataaaag aaacagaagg tgaaattgaa gttttaaaag
    22741 agtacctacc tcaacaatta agcgaagaag agttagaaga aattgtaaaa tctactatat
    22801 ctgaagtagg ggcaacttct atgaaggata tgggaaaaat aatgtcagtt atccaaccaa
    22861 aagttaaagg aagagctgac ggaaaactta taaataagtt ggtaaaacaa aacttacaat
    22921 agattgatat agcctagaga gaaatctcta ggctttttat agtttttggg aataacgagt
    22981 catatttgag catatctata atcaaagaaa attttgaaag aaggggaaaa atttgattat
    23041 atcagtaaaa gagattagga attttttgat aaacatattt ataccactaa taataggtta
    23101 cttaagtagc atcttaacaa tgattatcag tggaacagat atttcaacct attatttaca
    23161 actcacaaag ccaagctttg caccaccagc ttttatcttt cctatagttt ggactatatt
    23221 gtacatattg atgggtatat cttcatacct aatattaaga aagggttaca acttacctaa
    23281 agtaagagat gcaatttttt attatggatt acaacttgta ttaaacttta tttggagtat
    23341 actatttttt ggatttggac ttagatttac agctttgata gatataataa taatgatttt
    23401 ggtttctata ataatgattt cgaagttttc taaaatagat aagagatctg gatacataaa
    23461 tttgatttat ttaatgtggc ttgtttatgc aggatttttg aactatttta tatggtttat
    23521 taataaatag aatgtaaaga ttttgtaaat taccctgtac ttttaataat atcataacaa
    23581 acgaaaaata aatagactat taaaaataat cattttcata tacaataata ttaatttaaa
    23641 tacaataaat ttataaaaat tgtatttaaa gattaacata ttaaagtatt agaattggaa
    23701 aggcttgaag ggagaggttt ttatgcaaat aatagtatct gggagacaaa tgaaattaac
    23761 tgacggaata aaaggatacg tagatggaaa attaagtagg ttagaaaaat accttgatcc
    23821 tgaatcagaa gtgaaagtaa cagtaagtgc gaaaaaggat agacaaaaag tggaggttac
    23881 aataattcct attaacggtc aaataataag agcagaagat gtagaagatg acttatatgc
    23941 agcaattgat attgtttgtg acaaattaag tagacaagtt gtcaaatata aaactaaagt
    24001 taaagacaaa gttcaaaata ataagagcat aagatttgaa aatcttgact ttatagataa
    24061 tagcagtgaa tttgatgatt atgattatga tgatgaagaa gatgaaaata tagtaataga
    24121 aagaagaaag aaatttaatg taaaacctat gagttctgag gaggcgatac ttcaaatgga
    24181 actagtagga cacaatttct atatgtttag aaaccaagat aattttgaaa taaacatagt
    24241 gtataagcgt aaagctggtg gatatggttt aatagaacaa gattaataaa aattgtatac
    24301 gtttagattt tatataagaa aaaataaaaa ggtaatcatg ttgatttttt atcaatatga
    24361 ttaccttttt cttgtttaaa taatatatta gatattaggt atttattata taaaaatttt
    24421 aaaactaatc tgttacaaca tcaataaagt gcataaatac ctatttcaag cataaaatta
    24481 attaaggggg taatgcttat gttagaaata tccactgatt tacaagtaaa tcaaccagtt
    24541 attactgtta caagtaatac gtttattagt atagaaaatt atctatcaat attagaatat
    24601 gaagttgatt taataagaat aaagactaaa gttaaaacaa ttaaaatatc tggggataaa
    24661 ctttcactta agtatattac tgatagtgag ataggtataa aagggattat ctacaatgtt
    24721 gagtatgttg attaggagga gatacacttg ataagtttta taaggggata ctatgttata
    24781 gttgtggaag gagtaagact cgaacaattt ttaaatcatc ttataagaaa tgggataagt
    24841 gtttacaatg taactagaat aaaaaatact aaaatggagt ttcatataga tagacaagat
    24901 ataaaagaat ttaagaatgt ttatagagga agtaagtttg atataaaggt aaagcaaaaa
    24961 actggggtcc cttttattat caaaagagtt tataagcaca aaggtatgtg gatttgtgct
    25021 cttgtttctt tatttttatt gatgtctaca tcacagtttg tgacagatgt atatatacaa
    25081 tctcctgaag gtataaaaaa agaagctctt agaaatgagc tttataaggt tggagtaaga
    25141 ccaggagtct ataagaagag tattgataga aaagaagtta gagaccatat gatgtcaaaa
    25201 tttaatgatg tggcatattt atctatcaat gtaaaaggaa caaatatatt tgttactgtt
    25261 acaaaaaagg cagaatccct aaaatctaca gaccaatcaa attattgtaa tgtaattgct
    25321 ttaaaaaatg gtataataga aaaggtaatc cctagaagtg gtaaatcagt tattaaatct
    25381 ggagacatag tccaaaaggg agatgtctta ttaaatggag ctaataccaa gtcaatacca
    25441 gaagtatggg caagtacttt ttatgagtcc acaaaaaagg aaagttatgt agatactgta
    25501 aataaaaaaa ctggagaaaa gaaaaatata tatacactaa gtttttatga taaagagttt
    25561 acaatgagaa aaaatataaa atataaagat tatgttgttg aaaataaaga aaaaaaacta
    25621 tcaataggaa actatacttt tccaataaag ataaaaacga gtacttttta tgaaacaaaa
    25681 aaggttgaag taaaaaggaa taaagaagag ttaaaaaaag aattatctga aaaagcttta
    25741 aaagagttag aatacataat cccagcttcg gctagaataa tagatgtaaa acataacttt
    25801 aaggttaata aaaatatgtt agaatattta ataacagttc aaactagtga aaatattgct
    25861 aaaatttatc ctcttagtaa gtcagaagca gaaaggttta taaaggaaga aagtaaacca
    25921 gatgaaggtg aagaggaagt tccttccaat ccagaaaaaa gaccattaaa tgatataaga
    25981 aatgagtttg atgaggataa taaggataat aaagaccaaa acaattctga tgaaaataat
    26041 agtaatcaaa atagtaataa tagtcaaaat aataatagca ataacaacta ataaaattaa
    26101 acttaaaatc ttaggaggac taattcaatt gataatacaa aagaaattta caatagcaga
    26161 tggtaacttt gaaagagagt tatttggcaa ctttgatgaa aatgtaaaat taatagagaa
    26221 gactttaaat atagatgtaa tacttagaga aggcaatata attttaattg gagaagaaaa
    26281 aaatgtagat tctgcattaa aacttatgaa tgaattacac caaactgtat caaatggtaa
    26341 gcatttagat aagcagagta tttcttattc attatctctt ttgcttgaag gaagtgaaca
    26401 aaaaataaaa gaacttgagg ggacaatcgt cataactcaa aggggaaaag ctgttcaacc
    26461 taaaacttta ggtcaaaaag aatatataaa acttatagaa aataatgata taacttttgg
    26521 tgttggacct gctggaacag gaaagactta tcttgcggtt gctatggcag taaaagcttt
    26581 taaaagagat gaagttagta gaattatact tacaagacca gctgtggaag caggagagag
    26641 tctaggtttt ttaccaggag atttaaagga caaagttgac ccatatttaa gaccactata
    26701 tgatgcctta tttgaaatgt tgggtgctga taaatttaat aagtatttag aaagaggtac
    26761 tattgaggtt gcaccacttg catttatgag aggtagaaca cttgataatt catttataat
    26821 attggatgaa gctcaaaata ctacttctga acaaatgaaa atgtttttaa ctagacttgg
    26881 atttggctct aaagctgtag ttacaggaga tgtaactcaa acagatttac cacaaaataa
    26941 gaagagtggt ctaatacaag ctacagagat tcttaaaggt gttccaggta ttgggtctat
    27001 aatgctaaca gatagagatg ttgtaagaca tgagttggta cagagaataa taagagctta
    27061 tgagaagcac gacaaaagag aagaatttaa aaaagaagaa cgtaaaaaag cgaaaatgca
    27121 ggaaaagact ttcaaaagaa agtaaaagtg tagtaatata gatatatagc attattaatg
    27181 aataaaaagt aggtgtagtg aatggatttg atactagatg atagacaaga taaattagaa
    27241 gtaagtgagg agttaattga aaagataaag gatataatca tagaatgttt agattatgaa
    27301 ggatatgatg ataattatga agtgagtctt tcttttgtag ataataaaga gattcatgaa
    27361 ttaaatagag aatatagagg agttgataga gtgactgatg ttttatcatt tcctctttta
    27421 agtgatgatt ttgaggatgt tgagttagaa gaagaatccc taggtgacat agtagtatct
    27481 cttgaaagag ccttagaaca gagtatagag tataaccata gttttgaaag agaagtatgt
    27541 tttttaatat gtcatagtat gtttcatctt ttaggttatg accacgatac agatgaaaat
    27601 acaaaagaaa tgagagaaaa agaagaacac atattaaata agttaaacat aacaagggag
    27661 tagtttttat gaaaccagaa aaaactcgtc aaggtataat taaagcattt aatgcagcta
    27721 tagaagggat attgtataca tttaaatttg aaagaaatat gaaaatacat tatttaggtt
    27781 cagttgctgt tcttataata agtttgtttt ttaacttttc aaaattagaa atgataatgt
    27841 tacttatgtc catatgctta gttgtagttg ctgaaatgtt taatacagct atagaaaaag
    27901 ctgttgattt agtaactgat gaatatcatg ttcttgctaa gatagcaaaa gatgttgcag
    27961 ctggaggcgt tctagttgca gcactaaatt cagtagtagt tggatatatt ttgttttatg
    28021 ataaattgac agatatatct ggaatattaa tttataaaat aagagaatca gaattacata
    28081 taaccttgat atgtatatta ttggttctta tagctgttgt agttgtaaaa gcattgactt
    28141 ctacaggtac tcctctaaaa ggaggaatgc caagtggtca tgctgcctta gcatttgcta
    28201 tagcaactgc aattacactt atgactgaaa gagttgttgc ctctactctt gcatatataa
    28261 tggctgtatt agttgcccaa agtagaattg aaggaaaaat acataccttt tgggagacta
    28321 ttgctggagc tttgttaggt gtgttgatag ctatattagt atttcagctt ggaatgttct
    28381 ataattaaaa taaatgtaca taaaatattt aaaataaaac aaatctgtgc taattaaatt
    28441 tttatgatat aatgtagagt attaaataaa aataactttt aattattgta tacaggagga
    28501 gttgttgtgg ataacataga attgttaagg ttggcagaag atgccagaca acattcttat
    28561 gctccttact caggttttag agtaggtgca gctcttttaa ctaagagtgg taaagtttat
    28621 actggatgta atatagaatg tgcatcatta ggtggaacaa attgtgcaga aagaacagct
    28681 atttttaaag caatatcaga gggtgataag gatatctata aaatagctat agcaagtgat
    28741 aactcagaaa ataatgagca aacatatcca tgtggaatat gcaggcaggt aattatagag
    28801 tttggttctg atataaaaat aataacggga tatactaaag gagaggtgtt tgagcatagt
    28861 ataaaggatt tgttgccaaa ctatttctct ggaaatgatt taaaataaa
//
LOCUS       DAEOTL010000045        28590 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEOTL010000045 DAEOTL010000000
VERSION     DAEOTL010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28590
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.045"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(224..2503)
                     /locus_tag="KRH82_002364"
     CDS             complement(224..2503)
                     /locus_tag="KRH82_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8655638.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEVEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2774..4228)
                     /locus_tag="KRH82_002365"
     CDS             complement(2774..4228)
                     /locus_tag="KRH82_002365"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBG8655639.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVEIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4392..5261
                     /locus_tag="KRH82_002366"
     CDS             4392..5261
                     /locus_tag="KRH82_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655640.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDANSDLEK
                     CFKIATENKCNRLRLNIHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5474..7546)
                     /locus_tag="KRH82_002367"
     CDS             complement(5474..7546)
                     /locus_tag="KRH82_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8655641.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(7849..8691)
                     /locus_tag="KRH82_002368"
     CDS             complement(7849..8691)
                     /locus_tag="KRH82_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8655642.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(8952..10994)
                     /locus_tag="KRH82_002369"
     CDS             complement(8952..10994)
                     /locus_tag="KRH82_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBG8655643.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSIAQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(11146..12117)
                     /locus_tag="KRH82_002370"
     CDS             complement(11146..12117)
                     /locus_tag="KRH82_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBG8655644.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(12118..13095)
                     /locus_tag="KRH82_002371"
     CDS             complement(12118..13095)
                     /locus_tag="KRH82_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655645.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            13314..14873
                     /locus_tag="KRH82_002372"
     CDS             13314..14873
                     /locus_tag="KRH82_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655646.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAEIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            14979..15938
                     /locus_tag="KRH82_002373"
     CDS             14979..15938
                     /locus_tag="KRH82_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655647.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGILLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            15941..16753
                     /locus_tag="KRH82_002374"
     CDS             15941..16753
                     /locus_tag="KRH82_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655648.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIIASFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(16965..17867)
                     /locus_tag="KRH82_002375"
     CDS             complement(16965..17867)
                     /locus_tag="KRH82_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8655649.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            18222..19400
                     /locus_tag="KRH82_002376"
     CDS             18222..19400
                     /locus_tag="KRH82_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBG8655650.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVRLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            19409..20065
                     /locus_tag="KRH82_002377"
     CDS             19409..20065
                     /locus_tag="KRH82_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBG8655651.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            20065..20730
                     /locus_tag="KRH82_002378"
     CDS             20065..20730
                     /locus_tag="KRH82_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBG8655652.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            20835..21611
                     /locus_tag="KRH82_002379"
     CDS             20835..21611
                     /locus_tag="KRH82_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBG8655653.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            21673..23007
                     /locus_tag="KRH82_002380"
     CDS             21673..23007
                     /locus_tag="KRH82_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBG8655654.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            23504..24430
                     /locus_tag="KRH82_002381"
     CDS             23504..24430
                     /locus_tag="KRH82_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBG8655655.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPDNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(24823..28362)
                     /gene="nifJ"
                     /locus_tag="KRH82_002382"
     CDS             complement(24823..28362)
                     /gene="nifJ"
                     /locus_tag="KRH82_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBG8655656.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         9841 a         4563 c         3743 g        10443 t
ORIGIN      
        1 ttactatcta aagtattttg ctataatccc atatactctt acctcaaaaa cattcaaata
       61 gaaaaaatac tacataatta ataaactttg cccaataatt cctaaaataa tatcataaca
      121 atgatttatg ttttataata gtatattttt acataaaaaa gtgaacattg attaacaaag
      181 ttcacttttt tataaatttt tatgttataa ttcacaattt tatttaattt gtttcttttc
      241 tatttaaact atatctatct aatattaatt tttcatattc ttctattggc attggtctag
      301 caaataaaaa tccttgagcc atatcacaac ctataaacct taaaaactct gcttgctcta
      361 cagtttcaac accttctgaa acaactttta tatcaagttg ctttgccatt tgaacaatac
      421 ttgaaactac aatttgactc ttttttgcat ttcccactgt tataaagaat tgcctatcta
      481 atttcaatac atcaattggc atatctttaa gcatatttaa agaagaataa ccagaaccaa
      541 aatcatccat agaaatttta aatccaacag atttcaaagt ttgcattatt ttaaataata
      601 tttttgtatt gtcaaatatt gcactttctg tcaattcaat ctcaattaaa tttggttcaa
      661 cttcatattc ttttgttatt ctttcaagct cagaaataaa gcctggattc tcaagatgta
      721 ctcttgataa gtttattgat ataggaaatg tggggaaatt ttcattttcc caacgtttaa
      781 aatttttaca aacttgggta aatacaaaca tatccaattc tgttataaaa ccatttttct
      841 caaaaatagg aataaataca cctggactta ttagaccttt tttaggatgt tgccaacgta
      901 caagtgcttc agcacctaca attttagtag ttgataaatc aaccttaggc tgtaaataaa
      961 ctttaaattg ttcatttttt aaagcatcat gcatttcttg ttcaatatca cgttcttcta
     1021 tgagagtttc ttttaaattt tcagcataaa tctcataaac ttttaaatat tttcttttta
     1081 ctgtagtttt tgcaatcata gctttgtcaa gacaggtaga aatatttgtt tctccctctt
     1141 caacaaaata tacacctata gatggaatta aattgagttc tactcccaaa cttgttttta
     1201 tcattgacaa ttttttacgt ataagttcac atatttctat aattgactct ctattatttt
     1261 tcttttcaaa tattatagca aaattgtcat ttgaaattct tgaaaataca gattgctctt
     1321 taaatatatt cttaattatc tctgctattt cctttaatac tctatctcct tcttcatacc
     1381 caaacctatc atttactagc ttaaacttat ctatatcaaa ataaattaaa actagattct
     1441 ttttctcatg agaggataaa aattttcccc cttcaagatt aaatttattt gaattgccaa
     1501 tacctgtaac gttatcttta aaagcaaatt cttccaattt ttccttactc tttttatgta
     1561 taaatagtat ataaattgtt aatgccgtaa agattataat caagactaca catgctgata
     1621 atgtaagttt tataatagca tatgatttct cagatatagc agttttagga acttcagaaa
     1681 aaagatacca atcattgatt cctattgggg cataacttaa ataatatcct tttccaaaca
     1741 tactataact taatgaacct gatttaaagt tttttatatt tgacttcata ttattgatac
     1801 tagattttga tattgaatca cttctgccaa tgtaagaaaa taaattttct ttagtagagt
     1861 tggcgttttt actgcttgga tttaaaacaa tatcaccatt acttctagtt atataagaat
     1921 atccttttcc attaaatgta ggtacagaaa gtattttttc atacaacttc gtactatgtg
     1981 tggcaaatat aactccttta acctcattat ctttataaat tggtacagaa tatacattaa
     2041 tattactatt ggtattttta tcatcttcta ttacatcttt taattttcct gttataacca
     2101 cttctccttg cattgatttt aagaaataat ctcttttaga gaagtcttct atataaccat
     2161 ctgtagtgta tgctgtacca tttggtaaaa taactcccat tcttttaaat gaactattaa
     2221 tagcttgtct ttttagtata gaaaggatat tatctacttc aaaagactct tctccttcaa
     2281 taaatattga aattgactct agtaacttta tatctccatt aatttgtttt tttaacacat
     2341 tgacgctttg atttgctatt tctgaaagat attgattcgt ttcttcacct aatgtcttat
     2401 tcaaccttga accataaatc aaacaggaaa ttgtaattac taagatactt atgacagcaa
     2461 ttatggacaa accataccta ttattttttg catcacttaa cattatgctt cctgcctttc
     2521 tcgaatctat gtatgtataa tcattatctt atgacaatta ttgtaaacat tttataataa
     2581 tacttatttt tccatattta ctgtaattat acaaaattat aaactttatt acaacaataa
     2641 attaattaat atagatatta gtgtttatat tattgcatta tctattttac aattatttac
     2701 atataaaaaa atgtaatatc aaagtgaagc ttgatattac atttttgttc ttgtattttg
     2761 tttaattttt atgctacatc ttacttaaac actcatttgc aacttcttta tcatcaaaat
     2821 gatgcttaac tttacctata atttgataag tttcatgtcc cttacctgtt ataattacaa
     2881 catcatcctt ttttgccata cttatagctt ctgctatagc ttgttctcta tcaacaacaa
     2941 catggtaatt ttcttttttc ttgtcaattc cttcaagtat atcttttatt attgcctctg
     3001 gttcttcagt tcttggatta tcagaagtta taatacataa atcagaatat ttttgtccaa
     3061 ttgctcccat caaaggtctc ttttcagtat ctctatctcc accacaccca aacacagaaa
     3121 ttatttttcc ttctgcaaat tgttgagttg tctttagtac attttcaagt gcgtcaggag
     3181 tatgagcata gtctacaatt acgcttatac ctttatcatt tggaactgtt tcaaaccttc
     3241 ctgatactcc attagaaagt ctaaggcctt ctttatatat tggtttaggt atgccaagta
     3301 catagcaagc agctataact gctaaagtat tatatactgt aaacattcct ggaactggta
     3361 taaatattac ttcttcatat gaaggtgtta ttaatctata agatactcca tccgaatctg
     3421 attttatatc tctagccata aaatcagcct tagtatcaac accataagtg taacaaggta
     3481 catttatacc ttttatattt tcatatatct tttttccacc ttcatcatct atgtttatta
     3541 tatttgccat agtagtctta aaaaataatt tttcttttgc ttttctataa tcctctaaat
     3601 ctttatgaaa atctaaatgg tctggtgtta aatttgtaaa tatgcctagt ttaaagtctg
     3661 tttcatcaac tctatttaat gccaatgaat gtgatgaaac ttccatagca cagtagtcac
     3721 atccattatc caacatatta ttaaaatgat attgtaaatc tatactttct ggagttgttg
     3781 aattggaaac aatgtctttt tctccatcaa aaatttttat agttcctata agtccaactt
     3841 tattcttatt taaagttaat atctcattta gtatagtagt tatactagtt tttccattag
     3901 tacctgtaac tcctataacg ttaaattttt gagatggatg attgtaaaaa ttatcagcta
     3961 cttttgccat atcttttctt gtatctttta cctttataaa tgtacatcct tttatttcta
     4021 catcttcttc aacaagaaat gcacttgctc ccttttctat ggcatctttt atatacttat
     4081 gaccatctga cacaaatcct tttatacata taaataatgt accttttgta acctttcttg
     4141 aatcatattg tacattatta atatctatat ttaattcacc cttgacattg attatatcca
     4201 acccctgtat aatatcattt aatttcataa atgctttcct ccctttaaac tctttctgct
     4261 aaaattacac tacatataat attatattaa gaatttttta ctatgtgaat ggttaaaaat
     4321 gcttgaaaca ttgcaaaaaa tgctctataa ttttctataa tataactgag gaaaggtctt
     4381 ctataaaaac tatggataat aaaatcgggt acttaaacga taactttaaa atatttaata
     4441 ttagagataa aaaagatata caatttgaat accataatca tgattttaat aagataatta
     4501 tatttataaa tggaaatgta acttattttg ttgatggtat tccctataaa ctaaagcctt
     4561 gggatatact ctttatcagc aataatgaaa tacataaacc agttatagat tcaaatgtct
     4621 tttatgagag aattgcaata tggattagcc cagaatttat gaaaaaaaat agtgatgcta
     4681 atagtgactt agaaaaatgt tttaaaatag ctacagagaa taaatgcaat agattgcgtt
     4741 taaatataca tgatattgaa tctattaaga gttttattga gcaaataaat atttccgaat
     4801 ccaatactga atttggaaat gaaatattga gaaatacatt atttatacaa cttatgatat
     4861 tcttaaacag aattttccta aaaaatgaaa atatggaatc aacagaagac gttttttatg
     4921 atgaaactat taagaaagta ttaaactata taaattcaaa tatagatgat aagctttcaa
     4981 tagatagcat atcgtctgaa ttttttataa gtaagtatta tcttatgaga aaatttaaat
     5041 ctcatactgg aacgtctata cacaattata tagttcaaaa aagattaatt ttggcaaaat
     5101 cactaataac caatggtcac cttatgagtg aagtttgtaa taaatgtgga ttcaacgatt
     5161 attctagttt tgtaagggca tttaaaaaaa actacggtgt atctcctaaa aattatataa
     5221 acaataaaaa tcctttggat attactcttt tagatgaata gataatttat gtaaatttta
     5281 ttttaataaa acttgaagta ttagtgtatt tatcttacta atacctcaag ttttttaatg
     5341 ttttaaaata tatcaaaata taatgatata tatttctatt acttaaaata tatattaaat
     5401 aaattgcatg ttaactgaac ctatttatat atttattaaa tctcacataa cttttagtta
     5461 cactatcata tagctatcct attttttcaa tatcatctct taatatactt actctattct
     5521 cctcttttgc tgtggttact ccttttttaa tgcttaattt ctgattttgt tctaaattcg
     5581 taaatactac aggacttatt gttgatagac catttttttc aatatattct aagtccattt
     5641 taactaattt ttctcccgct tttacttcat ctcctacatt cacaaatact tcaaatccat
     5701 ttccttctaa atttacagtt tctatcccta aatgtataag tatttctact ccactttttt
     5761 gggattttat tattattgca tgcttagttg gaaatataac tccaatagtt ccatcaactg
     5821 gtgaataaat caatccatca ctagatttaa ttgcaaatcc atcccccatc agtttacttg
     5881 aaaatacaga atctggcact tcttctatat ctaatatctc tccatttgtt aatgaatcaa
     5941 tcttttctac taaagcattt tccatatttg caacttccat attttttttc actttatttt
     6001 tatcaacatt tttagtaaca gtactttcaa cctttgtttt tccctctatt atatctttta
     6061 tatcagactt tattgaatcc gattttggtc caaatatagc ttgaacattg ttgccaataa
     6121 ccataacacc tgctgctcca agtgatttca atttttcttt atctacttta tttatatcat
     6181 ttacaaccaa tctaagtctt gttatacacg catctaggct cttcaagttg tctttatttc
     6241 ctaaagcaat caaaatctct gatgctaatt cattcttaga catttcaatg acttcagcgt
     6301 tagtttctga ctcatcttct cttcctggtg tctttaaatt aaattttctt atcataaatc
     6361 taaatacact atagtataat actgcaaaac caatacctac caagatagcc aagtaccatg
     6421 gagttctatt aggaagaaca ccaaataata agaaatctat taatcctcct gaaaatgtga
     6481 atccaatttt aactcctaat aattgcataa ttgcgtatga taaacctgaa aataaacaat
     6541 gtattgcaaa taatactggt gcaacaaata aaaacgcaaa ctctattggc tcggttattc
     6601 ctgttaaaaa agaggttaat gctgctgatg ccattatacc tgctacaaat tttttctttt
     6661 ctggctttgc ttcatgcacc atagcaagag ctgctgctgg aagaccaaac atcataaatg
     6721 gaaatgcacc tgtcataaaa gtacctgctg tgaaatttac tccatcttta agttgagcaa
     6781 agaatatctt ttggtcaccc attacaagct caccagcttt atttacatat tctccaaatt
     6841 gataccaaaa tggattatgg aaaacatgat gcaaaccaaa tggtattaat agtctttcca
     6901 aagaaccttc cataaatgct gctagtgttt gatttgcttc tataacattt tttgagaaac
     6961 taagtaatcc ctcttgtatt ggaggccaaa taaaagacaa tataattcct attgctatag
     7021 caactaatga agtaacgatt ggtacaaatc ttttacctgc aaaaaaacct agatactgag
     7081 gtaattcaat tttataaaac tttttataaa gataagcagc cactatccct ataataatac
     7141 caccaaatac ccctgtttga attgttggta ttccaacaat atttgcatac atagaattgt
     7201 ctaccatatc ttctgtaaca cctgccataa cacccataga tgtattgaga attaaaaaac
     7261 ctactatggc tgccaatgct gcaacacctt ctccttcagt taaaccaaca gctaccccaa
     7321 ctgcaaatat aagtggtaag ttattaaata taatttgacc tgaactttcc attatactta
     7381 ttataagttg aaatgtagga ttcgccaaag ctggaaaatg agccaacaat gcgtctcctg
     7441 ctaaagcatt actcacgcca agtaatatac ctgctgcagg aagtaatgca actggtagca
     7501 ttagagattt tcctactttt tgtaaaacac caaatacttt tttcatttac ttttctctcc
     7561 ttattatttt atattttttt aaataaaaaa gacttaagtt tataaaaagt tacattagta
     7621 tacttaattc taaaattaaa cttatgttaa tataaacaaa cctatattaa cctaatttca
     7681 gaattaaaaa taaactatta taattttttt ataaacataa gtcttgcctg cattatcagt
     7741 aacaatctta atgttttaaa attattattt tatattaaat tttaaataat atattaaaat
     7801 tgaacataat atattaaatc tatacattct gtattaaact actctttatt ataaattcag
     7861 tacagatata actcttttga tatgtaatgt taaataaagt agttcatctt gacttacata
     7921 gtaatcataa ttcttttcta catgagtttt tattttatat gcacaatcat aatccttttc
     7981 atactttact ttaattatat ctataatttc attatttgta tcattgattt tttctttttt
     8041 tactaatcgt tttgcaaaga attttaaatg agtcagaagc ctatcataat ttatatcatc
     8101 ttctttaaat tcaactctat aataatatct tataatattt agtatgtctt ttacaatttt
     8161 agtaattaac agtgattcct ttgaacttcc cttatagttt gaatttacta tatgcattgc
     8221 tataaaacca gcttcatcta ctggaaattt cacatcaaat tctttattta tataatctac
     8281 agcccatttc ccaatctcat attctttttt atgtattctt tttatctcat gtagtaaatc
     8341 attctttata gttatgtttt catgatatct tttaattgca aatgcaatat ggtcagtaag
     8401 tgctacataa atatattcat aaagtttagt attcaaattc tcctctgcat aagcaattat
     8461 ttcagtacta acctcaaaaa atttctcatc aacctggctt gctagtttac taattttatc
     8521 taaaaagctt tcatcttgta ttacaaaagt tctttcaatt ttacttttat ctatttcttg
     8581 acctttcttt ttttgaaacc caattccaca tcctgttaat attaattctt tttttatatt
     8641 ttcatctaaa actaatacaa cattattatt ataaatttgt tgaataatca taatcaatat
     8701 ctctcccaaa atacaatttc ccttattcat aaaaaaatac ctaaattaag atacaattca
     8761 cctgtatacc ttaacctagg tattgcctgc ttaccagtaa caatccagct tgttaacgct
     8821 tatatattgt attcaattta tggttttatt ctattataaa taaatatata tgtcaagtaa
     8881 attattgaaa actatttcct attttttagt attaatttta acatcaaaaa tcaaatttta
     8941 ttccattata tttatgattc tatcatcatc atttcatcat agagaatatt ttccaataac
     9001 tctttagcca cttctcttga tatttgctta gtttcaacta attgttgaac actgtctctt
     9061 tgactttgta tcgccattac tctgtagtat tctactcttg cctcaaactt atcatcattt
     9121 tgaatctttc tagtaatcca attcaaataa cgattataga atctgattgc tattaaggcc
     9181 tcatgtctgt tatcttcatc agtattttta tttataaatg atatagcagt tttagtagaa
     9241 agtgcatatg catggtgaaa ctctttgatt atttctttat tctcagatac tatttttgta
     9301 attttttctt ttacttcttt ctttactttt ctatttataa tccacatgct tatttttaat
     9361 tttacaattt taaatataga tttttgaaca gattttcttg attttgtaat ataaaatcta
     9421 tacaatttaa aggctctatc agaaatttta ccatcttcta atagtttcaa aacagctaat
     9481 aatccctgtt ggtctgcttc tgcaatcatc atacttataa gtttattatc tggagtattt
     9541 agtattcctt tttctgagtc taccaactgt tcatttaaat catgtataac tggttgtact
     9601 tcttgtgctt tttcattact aagttttaaa atggcttctt tcaaaattag tttatatgcc
     9661 tctttatcag ataataaagg ttctgactct tgtacgttat tttttaataa tcttggcagt
     9721 aaaactgttg ccaatactaa acttataaga ataacttctg atgatataaa taaaacagta
     9781 tctctcattg gaaatacatc tttatcagcc aaataaaaag gtatagataa ggcagttgct
     9841 agtgtaaatg taccatgaac accacaagta gcaactatta gtgagtattt acatttagaa
     9901 atactctctt ttacaacttc ttcatcctta aaacctaaaa aacctacaaa aaaattattt
     9961 aaaggattct ttttaggttt tataaaagaa ttatgccata aatataccca tataaatctt
    10021 ataacaaata aaataagtac aattaaagta gaaataaaag tcaattccaa tgccatattt
    10081 tcatttttac tactaagtcc tgtatatata cttggtaaca aaaaaccaag cagtgtaaag
    10141 acaaatccat tcaatacata ctccaaaaca taccaagtat tgtctgatat tatccttaat
    10201 ttagtagttg tattttgtaa atgctctttt tcaattccat gagctatccc tgccattaca
    10261 acagctagga ttccagatac tcctatttct tctgctacaa aatatacaaa aagtggagtc
    10321 attatttgta taactattac cattggaatt tcttccaaat tccacttgtg taaactaagt
    10381 cttattttta taattatgta tcctaaaata cttcctacta ttattcctcc aaaagctgta
    10441 atcataaatt gaatccctgc ctcttctatt gaaaaaactc ctgtaactgt ggcaagtact
    10501 gcaaccttaa atgctactac tccagcagca tcatttaata aagattcacc ttcaagtata
    10561 ctcatcatat ttttaggaaa atttaatcct tgtgcaattg attttactgc tactaaatca
    10621 gttggagata ttactgctgc caaagcaaat gaaacagata atggcatccc aggaataaga
    10681 aaatgtataa agattccacc tgcaaacacg gttattaaaa ctaaaccaaa tgcaagaagc
    10741 aaaattggtt ttctgagctc taatagctct tttctcgata cattttgtcc ttcactgaat
    10801 agtaatggag ctatgataca tattacaaat atttctggat taaatgaaaa tgagaattta
    10861 aatggcaaaa tagacaatat aatccctagt acaatttgat atattgcaag aggaatatta
    10921 ctccactttt tgctaaatac agttgaaatc gttgtacaaa ccaataatcc caacaatgtt
    10981 actaaaattg acataactac ctctcttttc aataataata ttatagatta aacttatata
    11041 tcaactaact taatattaac agcatgaaat cccatcttaa tcaaaaaaat tttcagttta
    11101 ttctattatt cttattatat acatcaaatt taatttttga aatatctata ctagatgaca
    11161 tgcaacaaaa tgatttcttg atatttcttt taaaactgga atctcttttt tgcatatttc
    11221 cttacaataa gggcatcttg tatgaaactt acatccactt ggtggatttg ttggagatgg
    11281 tatgtctcct tttaatataa ttctattttt cttaattgta gggtcttgta ttggtactgc
    11341 gctcataagc gcttttgtat atggatgttg agaatgtaag taaagttctc ctttagttgc
    11401 aatttctatt atagaaccta gatacataac acaaactcta tgtgcaatat gatttactac
    11461 actcaaatca tgagatataa ataaatatga aagtttatat ttatcctgta aatccataag
    11521 taaatttata atttgagatt gaatagaaac atctagtgca gaaacaggtt catcacaaac
    11581 tataaattct ggatttaatg ctaatgctct tgctatacct attctctgtc tttgacctcc
    11641 agaaaactca cctggttttc tatttaaatg gtacttagaa agaccacaac tttctacaac
    11701 atttaatata ttatctttta tttcattctt tggcactaaa ttatgttcta taactgcctc
    11761 ggatattatt tgttccacat ttaatcttgg atttaatgaa ctatatgggt cttgaaatat
    11821 catttgcatt ttgggtctta actttctaag ttcttccttc tctaacttat atatatctac
    11881 accattaaat tcaactttac cttcagtttt ttcaattaat ctaagaatgg ttcttcctgc
    11941 agttgatttt ccacatcccg attctccaac tatagccaaa gtttctcctt tttttaaatc
    12001 aaaagaaatt ccatctactg cctttacaca tttaatttcc ttatcaaata atccagattt
    12061 aacttcaaag tactttttaa gaccctctac ttttaataaa ctctcttctt ttttcaatta
    12121 tatctcctcc tttttatata accaacatgc aatactatga ccactattca attctattaa
    12181 aggaggtatc tgagttctac atttatcaca tactttttca catctatcac taaaataaca
    12241 tgaatctggc atcccaattg gatttggtac ttgtcctgga atcgaataca atcttttatc
    12301 tttgtttttt ccaagagcag gctttgattt tagaagtcca atagtataag gatgttttgg
    12361 atttttaaat aattcaacaa cctctgccac ttctataatt ttgccagcat acatcactaa
    12421 tactttgtca cacatttctg caactactcc caaatcatgt gtaatcatca ttatagatgt
    12481 gtttaatttt tcttttatat ttttcattat atctaaaatc tgagcttgaa tagtaacatc
    12541 taaagctgtt gttggttcat cagctataag taattttgga ttacatgata aagccatagc
    12601 tatcattatt cgttgtctca taccacctga taattcatgt ggatatgaat tatatatttc
    12661 ttcagctctt ggtatttcta ccagttttat catatcgatt acctttttct tagcttcttc
    12721 ctttgataaa tcttgatgta tcataatacc ttcaatgatt tgacttccaa tagtaaacgc
    12781 tgggtttaaa gatgtcattg gttcttgaaa aatcattgat atctcattcc ctcttattcc
    12841 cataagttca tcttcattca tctttaaaat atctttgcct cgaaagatta tttctccacc
    12901 ttctattttt gatgttggaa gtaacttcat caaagacatg gctgttacag acttaccaca
    12961 tcctgattct ccaactattc caatggtttc accttcattt atattaaaac ttacttcatt
    13021 tacactcttt acaatccctt tatctgtatg aaaataaact tttaaatctt taacctcaat
    13081 tagtgcttta ctcattattt tctcctctca gcaaaattac ttaagataac atacaccttt
    13141 tgattgtatt ttataaaaat ttaaattaca acattttctt acattttatt atttttttct
    13201 attaattata ataatataat agttaatttc tatatatatt gatttaataa tgattactat
    13261 tatacaataa aaaatatgtg ttaaatatta ttttatggag gttttataag aatatgaaat
    13321 ttaaaaaatt ggcatcatta atcttagttt catcattaat gcttacattt acagcctgtg
    13381 cttccaatga taaagacaag tctagtggaa gcaaatctgg tggaactgtt gtaataccta
    13441 tggcaagtga cccagatata atcaatggag cttttgcaaa cgttaaagaa gactctcttg
    13501 catcaaatat agtttatgct cctctttata cttatgaaaa aggaaattta gtaaattatt
    13561 tagcagaaaa agtagatttt aaagatagta aggaattaac tataaaatta aaatccaatt
    13621 taaaatggca tgatggaaag ccaataactg ctgaagatgt cttatttaca tttaatacag
    13681 ttttagacga aaaacaaaat tcaccatcaa gacaatactt attggtgggt gagaaaccag
    13741 ttaaagtaga aaaaattgat gatttaacag ttaagattac tttaccaact gcaagtgaat
    13801 ctttcttata tggtatatct aaaatttctc caataccaaa acatgtgttt gaaggagaat
    13861 caaatatagc taagtcagaa aaaaataata atccagttgg ttctggtgca ttcaagttta
    13921 aggaatggaa aaaaggtgaa agcatagtat ttgaaaagaa tgcagattat tttggtggag
    13981 aacctaaggc agattctata gcgctaaaaa taattcctaa tgaagcatct caagaagcag
    14041 ctttaaataa tggcgaaatt tcacttatga agacatctgc tgaaggatat gaaaaggcaa
    14101 aatcaaactc aaacttacaa acttatactt atagtgaaga aagattaaac tacattgtat
    14161 ttaaccaaaa tatatcaaac atggctaaca aagaagtaag acaagcctta tcatatgcct
    14221 taaatagaaa tgaaatgata gaatcagcat atggaaaaga aggttctgta cctgctaaat
    14281 ctatattagt tccagaagca gacttctata cagaagaagg tgttgaagga tatgaccaag
    14341 atacaaataa ggctaaagac ttattggata aaagtggtgt taaaattgat aaattaaaaa
    14401 taggttataa cacaggtaga tttgggcata aaaactatgc cttagtagct caacaagagt
    14461 tgaaaaaaat tggtatagaa gctgaaatag ttccttatga aagtaaggca ttcttcaata
    14521 tactatttag taatagcacg gaatgtgata tgtatgtaaa tggttatgct tggggattag
    14581 aaccaaaccc atatagaggt atgtttgaaa ctggtcaata ttgcaaccaa actaaatatt
    14641 ctaatgctga aatagatgct ttatgggaaa aaggatttac tgagttaaac aaggaaaaac
    14701 gtgaagaaat atataagcaa atacaacagg atatatctaa ggatgcgcct atttacacta
    14761 tagattatga acaaaattta atggcagctc aaaaaaatct aaaaggaata aaagatgcta
    14821 aaccatctcc tgcaatatta tttgaagatt ggtctaaact gtatgtagaa taattgatgt
    14881 aaaattttat attattaatt agaaaaggag atgtctaaaa ataatattgt tttattattt
    14941 taaaacgaga catctctttt aattaggaga atttacttat gttaaaatta atattgaata
    15001 gagtaaaagt tttaatacct atgttaatct taatatctat attatcattt ggacttttag
    15061 aattagctcc tggtgaccca gcagatgcat atataaatcc tttaatgtct tcacaggata
    15121 ttgaaaatat aagggttaat atggggcttg ataaaccagt atatataaga tatttaaact
    15181 ggttgaaaaa cactttaagt ggaaacttag gtatttctta tataaaccat atgcccgtta
    15241 cagaacaaat tatggaaaaa atgggaaata catttattct tatgggtact tctttgatat
    15301 tttcaatatt ggtagctata cctcttggaa tacttttagc tgtaaataaa aattcaataa
    15361 ctagtaaagt atcatctgtt tttaattata taggtgtttc tataccttct ttttggatag
    15421 gtatgatact catttcaatt ttttcagtta aacttaacat tttcccatca ggaggtatgc
    15481 atactattgg aaatgatagt attggagatt tagtaaaaca tttagttttg cctgtaataa
    15541 ctttaggtct atataatact gctattttta caaattatgt agaagctagt gtaaatgaac
    15601 aattaaaaaa acaatatgtt attacagcaa gagcaaaagg attatcagaa aaagtcatac
    15661 tatttaaaca tgtcttgaaa aattcactga catcattggt tacaatccta ggcatgagta
    15721 tacaaaaatt agtcactggt gcatttgtta cagaagtagt tttctcttgg ccaggtatgg
    15781 gaagattaat gattgattca attttttcaa gagattatac tgtaattatg gcaataacta
    15841 tgttatcagc actattttta attttaggta atttagttgc tgatatacta tacttattaa
    15901 ttgaccctaa aataaaatct agcaaaggag gattctagtt gtgtttacaa gtatcttaaa
    15961 aaaattaaaa aaagataaat cctttgcttt tgcatgtatt actcttagca taataatcat
    16021 attaattata gcttctttta tattaaatat agactctaat gcaattgata ctacttctaa
    16081 acttcaagaa cctagcttaa agcatatctt tggtacagac gaacttggta gagattactt
    16141 ctctagagct ctttatggtg gaaggatttc acttagtgtt ggtattttat caatgcttat
    16201 ttctgtagta tttggtactg ctgtaggtgt tattagtgga tatattggag gtaagctaga
    16261 ccaattcttg atgagattag tggatatgct tatgagtata ccaagtttct tagttttgat
    16321 tgtattaaat acttatctaa cacctaaagt ttccactatt atactaatta ttggattctt
    16381 aagttggatg gaagtttcaa gaattgtacg tggcgaaaca ttaaaaataa aggaaaatga
    16441 atactgtcta gctgctaaag ctactggtat caaaactaga aatatactat taagacatat
    16501 agttttaaac ttaaaagaga ctattgtagt tgctggttcg ttaaatattg ctaatgctat
    16561 cttaactgaa tctgctctta gttttttagg tcttggaatc caattgcctc ttgcatcatg
    16621 gggtaatatg cttcaagatg ctcaaagaca tatttttgac aagttatatt tagctgtatt
    16681 tccaggatta cttatatttt taacagtcat gagtttgact ataataagca aaaaattttc
    16741 tagtaatact taacaaattt tatatagaaa ataaaaacag tgattatcta aagatataca
    16801 ctgtttttat ttttcgttta aaaaaataca tcttttgtat attataactt taaatactac
    16861 tctaccatgt tatgtaaagc ctattattgt tctcaaacat atagatgaaa aactattagt
    16921 ttattataat aaaaattgat ttatttgtta ttttaataac atttttaaga gttcttttta
    16981 ctaaagaaat ctataataaa tttaaataca tgttggtcta catggctata acgttctttt
    17041 ttaggtctac ataatataac tttccatgta ataggatgat taaaaggctt ttctataatt
    17101 ttgctatttt caaaaaaatc atgaactggt gatggtaaaa ttgttataaa atcagaattt
    17161 gtggttgata gcaacaaaaa atcccatgaa ccagacatta tatatctttt taacttaaca
    17221 ttttcatcag taaatttttg cattagctta tgatgtatca taaaagtagg attaaatatt
    17281 gcaagtaact gctcattcaa atcgttccaa tctatcttat ccttcttagc aagtggatga
    17341 tttatattta aaaatgctgt aagttcatct tcttgaagca catgttcagt tactacactt
    17401 ttatcaattt tatgtggatg taacaatact gcataatcta attcctgtaa gataagcatt
    17461 ctatttaagt catatgcacc cttctctact atatcaaatt ctatatctgg attatttgca
    17521 actaactgtg caactacatc tgaaaatgct attccaagta taagtggagg tattcctatt
    17581 ctaacttttc ctttaaattg aactgaatct tctcttaaat cttccatcat atttttgtat
    17641 tcatttatga tatgttctgc atttacataa aatctttctc ctgctggtgt taacccattt
    17701 aacctgcctt tatacctttc aaataaatat acatcttcac tttcttcaaa attttttata
    17761 atttgactta atgctggttg agatatgtga agtgtcttag atgctattga taaattaaaa
    17821 ccagatttca ctatttcaac aaaatatttc aactgtttta tatccatttt aaaccccctt
    17881 ccccaaaagt ataatttaga ttatattttt tcttctaatg atattttata ggaaaatcaa
    17941 cataatttca ttaatatttt aacaaaatat ttttctaaat ctactataaa tttttatcct
    18001 ataaattttt cttatacact atataaaaaa ttagacttag acaaaacgct tttttcgccg
    18061 taatctataa ttagaaacag gaaaacctaa agcattagga ataaaagtaa ttgaaatact
    18121 taaaaacaag cttgtattaa aaaagtactt tattatagtg ttccctaatt tctttattca
    18181 gaaaattttt aattatcatt caagaaaggt aactattaga tatgaaagat gtagtaatcg
    18241 tatcagcagt cagaacacct ataggaagtt ttggaggtgt atttaaaaat acttcagctg
    18301 ttcaacttgg aactatcgct gttaaagaag cgatatcacg tgtaagactt aatttatctg
    18361 aaatagatga agtaataatt ggaaatgttc ttcaaacagg gcttggacag aatgttgcta
    18421 gacaaattgc tataaatgca ggtataccaa attctgttcc aagctacaca gtaaataaat
    18481 tatgtggttc agggcttaaa agtgtccagc tagctgccca atcaatcaca tctggtgaaa
    18541 atgatgtggt aattgcaggt ggtactgaaa atatgagcca agctccttat atcgttccaa
    18601 ctgctcgctt tggtagtaaa atgggtgaca taaccatggt agatagtatg ctaacagatg
    18661 gccttattga tgctttcaat cagtatcata tgggaataac tgcagaaaat attgcaacta
    18721 aatttgaatt tactagagaa atgcaagata aattggcatt agaaagtcaa aataaggctg
    18781 agaatgctat aaaaaacaac cgctttaaag aagaaatcgt tccagtagat gttttaatac
    18841 gtcgaggaaa aatagaaact attgataaag atgaatatcc taaattaggt atgacatttg
    18901 aaggtttatc taaacttaaa cctgcattca aaaaagatgg tactgtaaca gctggaaatg
    18961 cctcaggtat taatgatggt gcggctatgt taatactaat gagccaacaa aaagcagacg
    19021 aactaggtat tagaccactt gctaaaataa aatcctatgc ttcagctggt gttgaacctg
    19081 aagtcatggg tactggtcca atccctgcaa ctagaaaagc actgaaaaaa gctgggctta
    19141 gcatcaatga tatagactta atagaagcaa acgaagcgtt tgctgcccaa gcattagctg
    19201 ttaaaaatga acttcaaata gattcatcaa agttaaatgt taatggtggt gcaatagcat
    19261 taggacatcc aataggagca agtggagcta gaatacttgt taccttaatt tatgaaatgc
    19321 aaaaacgtaa agttgaaact ggacttgcaa cactttgtat tggtggtggt caaggaatat
    19381 caatggtggt ttcacgatag gaggaaatat gaataaaata gttagcattg atgaagctct
    19441 atctcatgta aaagatggag atacaataat ggttggtgga ttcatggcca atggttcacc
    19501 agaaaattta attgattatt tatgtagtaa aaatataaaa gatttgacac taatttgcaa
    19561 tgatactggc tttattgaca aaggagttgg caaaatggtt gtaaataagc aatttaaaaa
    19621 gataattgct tctcatgtag gattaaataa agaaactgga agacaaatga acaacaatga
    19681 aacagatgtt gagttagttc ctcagggaac tcttgctgaa caaatacgtg cagctggtta
    19741 tggtctagga ggtatactca caccgactgg tattggtact cttgttgagg agggaaagca
    19801 aaaaattgtt gtcgatagca aagaatacct tcttgaaaaa ccaatttatg cagatgttgc
    19861 tcttctattt gcatcaaagg tcgataaagc aggtaatcta gtttataaag gctctatgaa
    19921 caattttaat aatttaatgg catctgctgc caaaattaca atagttgaag cagatgaaat
    19981 cgttgaaatt ggtgatattg acccaaatga agttaataca ccaggtattt ttgtgaatta
    20041 catcgttgaa ggaggtaatt tataatggat aaattagaaa tgcaagaata tattgcaaat
    20101 agagtatcta aagaattaaa agacggagcc gttgtaaacc ttggaatagg tctaccaacc
    20161 aaagtagcaa attatattcc ggataatgta aacgttatct tacaatctga aaatggcttt
    20221 ttaggtttag gttcagccga agatggaaat tcaagtgatg aaactattgt aaatgcaggt
    20281 ggtcaaccag ttactatact tcctggagga tgtttctttg atagtgctac ttcttttgga
    20341 ataatcagag gaggtcatgt tgatataact gttcttggcg cacttcaggt tgacaaatat
    20401 ggcaatatag caaactatat gattccaggt aagatggttc caggtatggg tggagctatg
    20461 gacctagtaa ctggagctaa aaaagttatt gtagcaatgg aacatacttc aaaaggttct
    20521 gcaaaaatat taaataattg tactcttcca cttactgcaa caaatgctgt agatttgata
    20581 gttactgaaa tgggagttat ggaagtaaca tcagatggaa ttttacttaa agaaataaat
    20641 ccagctttca cattagatga tgttatttct gctactgagg ctcctttaat attgtcagat
    20701 tcattaaatg gaaaaatatc tgttgtttaa aataattaaa actagaaaat aaaaatctct
    20761 tagacgtatt acatataaat ttgtattgct taaaatatta atataaaaat aaaataaaat
    20821 tggaggaaat gaaaatggtt aaagataaag ttgtattcgt aacaggagct gcaagtggaa
    20881 taggtaaaca aatagctgaa tcgttcttaa aaaatggtgc taaagtaatg ttctctgata
    20941 taaatcaaga agctttaaat aataccataa cagagttaca aaaaaaaggt tatgattgca
    21001 tgagtgtaaa gtgtgatgta actaaggaag aagaaattaa ccacgctata gacaaaactg
    21061 ttgaaaagta tggcagatta gatatattaa taaacaatgc tggacttcaa catgtttcta
    21121 tgatagaaga tttcccaact gataaatttg aatttatgat aaaaataatg ctgacagcac
    21181 cttttatagc tactaaaaaa gcatttccta taatgaaaaa acaaggcttt ggtcgtataa
    21241 taaatatggc ctcaatcaat ggtgtaatag gatttgctgg aaaggctgct tataactcag
    21301 caaaacatgg acttattgga ctaacaaaag ttgctgctct tgaagctgcc gattctggta
    21361 taacagttaa tgctttatgc cctggatatg tagatactcc acttgtcaga ggtcagttca
    21421 atgacctttc aaaaactcgt aatataccat tggaaaatgt cttagaggaa gttttatacc
    21481 cacttgtacc acaaaaacgc ctattagatg ttcaagaaat tgccgactat gctatgttct
    21541 tagcaagtga taatgctaag ggtattacag gacaagcttg cttactagat ggaggatata
    21601 ctgcacaata gttattatat ttagggcttg aagaaagtat tcttcaggtc cttctactaa
    21661 ggagggatat ttatgagtat tatcgcgcca attggtataa ttattggtat catagctatt
    21721 atatattttt cagttaaaga aattcatata actatagctg ctccaatagc aactttaata
    21781 gttgttattt taaataaaat ggatgttgta acgtcaatgc taggtgctga caaaaacaat
    21841 tatatgggtg cacttggaaa ctatataatg agttattttg caatattctt attaggctca
    21901 atacttgcta aatttatgga agaaagtgga gctactgtat caatagctga ttttatttta
    21961 aataaatttg gctctaatca tccttataga gttttagttg ctatatttat agtaagtttt
    22021 atattaacgt atggtggtat aagcttattt gtagttatgt ttgcggtcat tccacttgca
    22081 agaactctat ttaaaaaact tgatatttct tggaacctta ttcagatacc actttggctt
    22141 ggtattgcaa caattactat gactataatt cctggaacac cagccattca aaatgttata
    22201 cctattcaat atctaaatac gtctcttact gcagctacta taccaagtat tgtaggtagt
    22261 ataggttgtg ctacgtttgg acttgtctat atgaaatatg ctctaaacaa aagtattaga
    22321 aaaggtgaaa cttatgcaac ttatacttca gaattagaag aagaatcttt agatagagaa
    22381 ttaccaggat tttttgcaag tatttttcct ctattagcac tcgtaattat agctataact
    22441 ggaagtactt ttggttcaga atttatgaaa aaaaatgtaa tttacatagc tttaatagtt
    22501 gcaattcttt tatctgcttt tttattccat aaatttctat catctaagat acagacattg
    22561 agcataggtg ctagtggttc tataggtcct atatttgcta catcttctgc agttgcattt
    22621 ggagcagtaa taatggctgc acctggtttt gatgtattta gcaaacttat aatgtcaata
    22681 ccaggtagtc cacttataag tcttactgtt ttgacttcaa caatgtcagc aataacaggg
    22741 tcctcttctg gtgcattagg aatagtaatg ccaaactttg cagattatta tttaagtact
    22801 ggtctaaatc cagaattaat tcaccgtgtt gctacaatag cttcaaatat actaactata
    22861 gttccacaaa gtggtgtttt tcttacattc ttaagcttat ctaagttaac acataaaact
    22921 ggatttaaag aaactttcat tgtagttgca gttggttcac taatagcaga aattattgta
    22981 attacattag gattactaat gtattaatat aaaacaaatt aaaattcata atatgaaagg
    23041 tggtgtctca aagtgaactt tttacttaat gagacactct ttttatatga aataacatat
    23101 gcctatcatt taaacaataa aaaagaacct tatctctatt ttgagacaga ccctttttat
    23161 ttcttaaaga tttaaataat tataatttgt tgctaatacg aaagcatcta ctgaataaat
    23221 ttaaccaaat aaaaaaaaat ttatcataac tataaattta cgttatggaa ttattataaa
    23281 aatattattt tctctaacta agtaattcca tactatacag gcttttaata caaattgtca
    23341 aacacactga aatataccta tttattccat atatatcttt tttacatatc tttacagtaa
    23401 aaaaagtctt aatcttatgt tagtatagat tcacgggtaa ccccctacac taaaggttac
    23461 aaatcagtaa catttttaga atttttagat taagaggtgt ttaatgatga gaagaaatat
    23521 accaacaaaa ttaaaaacta tattagcttt aggagtgtta actttagcaa cagcttcaag
    23581 tgctgttact gcaagtgctt catcacttga aaataatgta aatataagta acaaaagttt
    23641 agtatatagt aatactaaat acaagttttc tgcaaaacca aattgttctg taaaaccaga
    23701 acttaagcct gataaagata actcttgtaa ggataagaat cataatgaca agaattgcaa
    23761 caacactaat aaacctgagg acaacaataa ttcagactct actaataagc ctgataacaa
    23821 taaacctgag tctaataaac ctgaagacaa caataattca ggctctacta ataaacctga
    23881 taacaataaa cctgagtcta ataaacctga agacaacaat aattcaggct ctactgataa
    23941 acctgataac aataaacctg agtctaataa acctgaagac aacaataatt cagactctac
    24001 taacaaacct gatgataata acaactcagg ctctacaagt gaaagttttt cagcttacca
    24061 aaaagaagtt gttgacttag taaatataga aagagctaaa gctggattaa atcctcttac
    24121 tcttgattct tctatatcaa atgttgctac aaaaaaatct caagatatga ttgataacaa
    24181 ctatttttca cacaattctc caacttatgg ttctccattt gacatgttga aaaaatttgg
    24241 aataagctat aagacagcag gtgaaaatat agctatgggt caaaaaactc ctaaagaagt
    24301 tgtaaacgca tggatgaatt ctgaaggtca cagaaaaaat ataatgaatc caaatttcag
    24361 taaaataggt gttggagtag cacaaaaaag tggtggttca atttattgga cacaaatctt
    24421 tgtaggataa aatactcttt ttccatacat atcaagagag tatctctaag tgataaaaaa
    24481 cacaaatgag atactctttt gtatctattt taaaattatc aaatccaaat atacatacta
    24541 taaatattat ttgttctctt aattttagtg tgtaaaacaa tatataaaaa gtattggcaa
    24601 gatgaaaatg gaaaacttaa aaaagatatt taataggtaa aaacaaaatc ttaatatctt
    24661 cataaaaaaa ggctgtctca aaatagagat aaggcctttt tcattgttga aatgattaaa
    24721 atatatttga tttcatacaa aaagagtgcc tcatgaacta aaaagctcac tttgagacac
    24781 tctcttttat caattctata taagcattat aatactttaa tattattcag ctaatttttt
    24841 gtatccttca tatctttctt tagcatcagc ttcagcttta gcaaataatc catcagcttc
    24901 ctctgggaat tgtttagcta tagcagaata tcttacttgt gcaagtatga aatctttgaa
    24961 gcttgcagtt ggttcttttg aatctaaagt gaatgggttt ttaccttcag cttttacttc
    25021 tggattgaat ctgtataaat gccagtatcc gcaagcaaca gcttgtgctt cgttagctac
    25081 agttcttccc ataccttctt ttaatccatg gtttatacat ggagcataag ctattattaa
    25141 agatggccca tcatgttttt cagcttctat aacggctttg ataaattggt ttttatcagc
    25201 acccatagca acttgagcta catatacgtt tccatatgtc atagccatca ttcctaaatc
    25261 tttctttcta gattttttac ctgaagcagc aaacttagcc atagcagcag ctggagtagc
    25321 tttagaagct tgacctcctg tatttgaata tacttctgta tcaaatacaa gtacatttac
    25381 atcttcacca gatgcaagaa catggtctaa tccaccgtaa ccgatatcat atgcccaacc
    25441 gtctccacct agtatccatt gagatctctt aactagataa tcttttctat cttttatagc
    25501 ttttactaat tctttagctt tttcatctgt acaatcacaa gctggttttt ctaataattc
    25561 aacaacctta gcacttgcta ctttagaagc ttctccatca tttctagaat ctaaccactc
    25621 tgtaaatact gctttagcat cttcacagat atccatagaa actaactctg tcatagcatc
    25681 tactatttta tttcttattt gcttaacagc tgtgtacata ccaaatccat attcagcatt
    25741 atcctcgaat aaagaatttg cccaagatgg acctttacct tcatggttac aagtataagg
    25801 aattgatggt gcagaagctc cccatataga agaacatcca gtagcattag ctatcatcat
    25861 tctatctcca tataattgtg taactacttt aatgtatgca gtttctccac atccagcaca
    25921 tgctcctgaa aactccatta atggttgtct aaattggctt cctttaacag tgtttgcagg
    25981 cataacatca ccttttggag ctacctcatc aggatttact gcaaatgccc aattatctaa
    26041 ctctgtatca agttgagtat ctattggctt cataactaaa gctttttctt tagctggaca
    26101 tatgtcagca cagtttccac atcctgtaca gtcaagtggg ctaagttgca ttctatattt
    26161 taatccttct aatcctttac ctaatgcttt tttagcttca aatccttctg gagcattagc
    26221 taattcttct tcagtaacta atactggtct tatacatgaa tgaggacata taaaagaaca
    26281 ttggttacat tgaatacagt tatctattat ccattcagga acatcaacag ctataccacg
    26341 tttttcataa gctgcagtac cacaagggaa tgttccatct tctataccat tgaatgtact
    26401 tactggtaag ttgtttcctt cttgtgcagt cattggtctt agtatatttt ttataaattc
    26461 tggttcttta acttctcctt tatctgcatc aacagcattt tcccaagaag ctggaacttc
    26521 aactttaact aaagcattta ttcctgcatc aacagcagca tagttcatgt taactatttt
    26581 ttcacctttt ttaccataag ctttaactat agaatctttt aagtatttaa cagcatcttc
    26641 ttctggtatt atttcagcta atttaaagaa tgcagattgc attatcatat ttattctgtt
    26701 tccaagacct atttcttgtc ctagtttaac agcgttaact gtatagaatt ttatatcatt
    26761 tttagctata tattgcttca tatgagctgg taaatgttct tcaagtcctg cttggtccca
    26821 tatagtgtta agcacaaatg taccaccttt tttaagacct tttaataaat catattgata
    26881 aacatatgat tgtttatgac aggcaatata atcagcttca tctattaaat aagtagctct
    26941 tattggagta tcaccaaatc ttaagtgaga catagttata ccaccagatt ttttagagtc
    27001 ataatcaaag taagcttgag catatttttc agtatggtca ccgattattt tgatagcttg
    27061 tttattagct ccaacagtac cgtcagaacc taatccccag aacttacatc ttatagttcc
    27121 tttagaagct atttttattg gctcagatgg agttaaagaa gtattagtta catcatcaac
    27181 tatacctact gtaaatccat ttttaggttg ttctgaaact aagttatcaa aaacagtttt
    27241 tatatctgaa ggagtagtat cttttgaacc taatccgtat cttccaccta ttatcatagg
    27301 agcattttct tttccataga atacatcacg tacatctaag tataatggtt caccagttga
    27361 acctggctct ttagttctat caagtacaca tattctttca acagtagatg gcatagcatc
    27421 taagaaatgt ttcattgaga atggtctata taaatgaact ttaactaaac catatttttc
    27481 tcccttagca tttaagtaat ctatagtttc ttctatagtt tctgttactg aacccatagc
    27541 tattaataca tatttagcat cttctgctcc atagtaatca aataaactat gttttctacc
    27601 tgttaaatta ctcatttttt ccatgtattt ttcaactata cctactatat tttgatagta
    27661 tttattagaa gcttctctag tttggaaata tatatctggg ttttgagcag taccacgagc
    27721 aactggatga tttggagata aagcattatc tctaaatgct tgaactgctt caaagtttaa
    27781 taaacttgca taatcttcat tttctagtaa ttcaactttt tggatttcat gtgaagttct
    27841 gaatccatca aagaaatgta taaatggtaa tctaccttct attgcagcta aatgtgcaac
    27901 aggtgctata tcagctactt cttgaactga accagaagct aataatacac atccagtttg
    27961 tctagcagcc ataacgtctt ggtgatcccc aaatattgat aacgcttgag atgctaaagc
    28021 acgagcactt acatggaata ctcctggtaa caactctcct gcaactttat acatgttagg
    28081 tatcattaat aataaacctt gagatgctgt aaaagtagaa gttaaagctc ctccttgtaa
    28141 agaaccgtgg aatgttcctg atgcacctgc ttctgactgc atttcaacaa cattaactgt
    28201 ttgtccaaat atattttttc ttccttgtga tgcccactca tcaactactt cagccatagt
    28261 tgaagatggt gtgattggat atatagctgc tacatctgta aacgcatagg caacatgagc
    28321 tgcagctgta tttccatcaa gtgttttcat aaacttagcc ataatatgta tcctccttga
    28381 tagctacaat tgtacttgtt tataacaagt ctattttttt atatttacat ataatttaca
    28441 caacaaaaat ataaacacac atatagtcgc gcaaatactc tatcttctaa tataatacta
    28501 cagattagat aaaattcctt tgaaaattgt aaattaatta catatttaag tagatttttt
    28561 ttaaaattaa atatgttaag tttttttcat
//
LOCUS       DAEOTL010000046        28507 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEOTL010000046 DAEOTL010000000
VERSION     DAEOTL010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28507
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.046"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(219..1055)
                     /gene="nadC"
                     /locus_tag="KRH82_002383"
     CDS             complement(219..1055)
                     /gene="nadC"
                     /locus_tag="KRH82_002383"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBG8655657.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            complement(1036..2337)
                     /locus_tag="KRH82_002384"
     CDS             complement(1036..2337)
                     /locus_tag="KRH82_002384"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBG8655658.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(2350..3264)
                     /gene="nadA"
                     /locus_tag="KRH82_002385"
     CDS             complement(2350..3264)
                     /gene="nadA"
                     /locus_tag="KRH82_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBG8655659.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            3682..5139
                     /locus_tag="KRH82_002386"
     CDS             3682..5139
                     /locus_tag="KRH82_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBG8655660.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            5362..5790
                     /locus_tag="KRH82_002387"
     CDS             5362..5790
                     /locus_tag="KRH82_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655661.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            5850..6158
                     /locus_tag="KRH82_002388"
     CDS             5850..6158
                     /locus_tag="KRH82_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBG8655662.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(6305..7327)
                     /locus_tag="KRH82_002389"
     CDS             complement(6305..7327)
                     /locus_tag="KRH82_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBG8655663.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(7502..8008)
                     /locus_tag="KRH82_002390"
     CDS             complement(7502..8008)
                     /locus_tag="KRH82_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBG8655664.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            complement(8068..8769)
                     /locus_tag="KRH82_002391"
     CDS             complement(8068..8769)
                     /locus_tag="KRH82_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655665.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            complement(8987..10057)
                     /gene="buk"
                     /locus_tag="KRH82_002392"
     CDS             complement(8987..10057)
                     /gene="buk"
                     /locus_tag="KRH82_002392"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBG8655666.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            complement(10110..10685)
                     /locus_tag="KRH82_002393"
     CDS             complement(10110..10685)
                     /locus_tag="KRH82_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBG8655667.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(10687..12474)
                     /gene="iorA"
                     /locus_tag="KRH82_002394"
     CDS             complement(10687..12474)
                     /gene="iorA"
                     /locus_tag="KRH82_002394"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBG8655668.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            complement(12535..13794)
                     /locus_tag="KRH82_002395"
     CDS             complement(12535..13794)
                     /locus_tag="KRH82_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8655669.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKVLDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            complement(14056..16056)
                     /locus_tag="KRH82_002396"
     CDS             complement(14056..16056)
                     /locus_tag="KRH82_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655670.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(16064..17950)
                     /locus_tag="KRH82_002397"
     CDS             complement(16064..17950)
                     /locus_tag="KRH82_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8655671.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYPFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNGTRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCHSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            complement(17977..19818)
                     /locus_tag="KRH82_002398"
     CDS             complement(17977..19818)
                     /locus_tag="KRH82_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8655672.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(19949..20368)
                     /locus_tag="KRH82_002399"
     CDS             complement(19949..20368)
                     /locus_tag="KRH82_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBG8655673.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            20681..20863
                     /locus_tag="KRH82_002400"
     CDS             20681..20863
                     /locus_tag="KRH82_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655674.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            21192..22214
                     /locus_tag="KRH82_002401"
     CDS             21192..22214
                     /locus_tag="KRH82_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBG8655675.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKIRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(22299..22901)
                     /locus_tag="KRH82_002402"
     CDS             complement(22299..22901)
                     /locus_tag="KRH82_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBG8655676.1"
                     /translation="MKSLKKILIVTGCLTLISTSLVFASTNNDVNVSKSNEEQTTNSF
                     TITGYEFIYENAPQPIKSDYEKKCKELNINPSKDDTIFINEKFIDSYNINIDDYNIEP
                     KAFIIRYKKDLNRFDVTGPISYSVNINTTVVGYGHVEKGNPVHLVQLLCQQINGSDID
                     PDSKFGPATYNQVKILQGRLGVTKDGVVGKATWQAAGERY"
     gene            complement(22952..23986)
                     /locus_tag="KRH82_002403"
     CDS             complement(22952..23986)
                     /locus_tag="KRH82_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBG8655677.1"
                     /translation="MNNYMLYVFDNLIKTTIVCSFGICLLLFLKIYFFKRFSKRFNYY
                     IWLVIVFRMLLFLFNYTVMYEVKDPKENTVGNNITQIDISIDNDFMLYLVYLWLFVTI
                     AIAVYTFIEYTKFKNLVVDVSYDIEDNDVNCIYKNLLKELDIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYTYSKDELTWILKHELMHFKNKDILIKFLVLSVKIMYWFNPLVYI
                     MSNKVNLDCELCCDESVLTDCSLKDKKAYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLDSIIKKKGKSGILMLLILFTLFSVTYFNFESISFDNSNYLRNIGILEKTGADLKE
                     EDDISMRVVN"
     gene            complement(23979..24356)
                     /locus_tag="KRH82_002404"
     CDS             complement(23979..24356)
                     /locus_tag="KRH82_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8655678.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDATVTSKDVIEVMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTVIVKHKDYLSFETKDFLSNIHDDSLKSLISALH
                     DDENIGKDTLDFLESYFDNLKNE"
     gene            24859..25771
                     /locus_tag="KRH82_002405"
                     /pseudo
     CDS             24859..25771
                     /locus_tag="KRH82_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(25967..26554)
                     /locus_tag="KRH82_002406"
     CDS             complement(25967..26554)
                     /locus_tag="KRH82_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBG8655679.1"
                     /translation="MKNLKKILIITGCLTLISTSLVFANTTTDVDTSKDDDSIISSCT
                     ITGYEFTYENAPQSVKFDYEKKCEALNIKPSKNDIIFVNKDSIDANDVENYVEPKAYI
                     IRYKKGYVFEVTGPKSYTLNVSNTVVGYNRVESGNPVHLVQLLCRTLDGSSIDDDSEF
                     GPATYNAVKSLQGRLGLTRDGIVGRSTWDAAGRRL"
     gene            complement(26620..27654)
                     /locus_tag="KRH82_002407"
     CDS             complement(26620..27654)
                     /locus_tag="KRH82_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBG8655680.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENAVRNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELVSPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLIDCSLKNKKEYALALIKSIKLSKNYNSGILTTEFNKTSLE
                     KRLDSIVKKKGKSGILVLLILITLFSVTYFNFESISFDNSNSLRNMGILQKSGVDLKE
                     EDDISMRVIN"
     gene            complement(27647..28024)
                     /locus_tag="KRH82_002408"
     CDS             complement(27647..28024)
                     /locus_tag="KRH82_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8655681.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
BASE COUNT         9604 a         4707 c         2982 g        11214 t
ORIGIN      
        1 ttacagatac aattatatta taagtttatt cttatttatc tgtaaaatag atattaacta
       61 tattattaaa agtgtatata gtatttatct atttttatta aattattgat tgattttttt
      121 ctatttttat taattttaat gaataaaaaa tagactcctt aaatttataa aacaaattta
      181 aggagtctat tttaattaag tttatttcaa tataaaattt atatatttct caaattcttc
      241 atacttatat cgagagcttt aacagaatgt gtaagcgctc ctacagaaac aacatccaca
      301 ccaatttttc ctatatcttc tatagtatct aaatttacat ttccggaaaa ttctacaatg
      361 gctcttccat ttataatatc tactgcttgt tttgccattt ccaaactcat attatccaac
      421 attattatat ctgcattagc ttctattgct tcttttacca tgtctaaagt ttccacttcc
      481 acttctatct ttctaacaaa agaagtattt tttctagcta attcaactgc cttcttaaca
      541 ctaccagcag ccccaatatg gttgtcttta agcaatattc catcagataa attaaatcta
      601 tgattgcatc ctccacctac tttaacagaa tacttatcta atattctaag attaggtatc
      661 gtttttctac tatctaataa ttttgtattt gtaccttcaa gcttttcaac atacctactt
      721 gtaatagtag ctataccact cattctctgt aaataattca atgctacacg ctctcctaca
      781 agtaagtttc tagtactacc tgttaataca gctatctttt cacgattctt tactctatca
      841 ccatcatttt tatataattt tacatctaca tcaccaagta tctcaaaaac tctcttaaat
      901 acacctaagc cagctattat accatcttgt ttacaaatta aatctacagt agatttagaa
      961 ttttcatcca caatagaatt agttgttata tcttcacttg gaacatcttc tatcaaagca
     1021 tcctgtatca ttctatcaat aatcaaataa ttcatcgcca aaatcctcac ttgttctttc
     1081 aatttctttt atgactaata ttttattttc tttttttacc tgttctatat ctatatccat
     1141 atctggtaca tctataaact taacttttac attatctata actgagttta tatttttagc
     1201 tgctcttttt gaaaatacaa gcccttcaag taatgaatta cttgccaatc tattggctcc
     1261 atgaacacct gtacaactaa tttcaccaac tgcatataaa ttttccatag atgtttttga
     1321 atccaaatct acatgtatcc cgcccataaa ataatgttgt gcaggagata cctttataca
     1381 ttctttcgtt atgtctgttc ctctagctaa acattcatta taaataaaag aaaatctatt
     1441 aattaaatat tcactatcta aatgtgttgc atctaaatac acataaggta atttatcttt
     1501 ttccatttgc tcaaaaatag cttttgaaac tacatctcta ggaagaagtt catccacaaa
     1561 tctttcttta tttttattta aaagtttagc tccctctcct cttaatgatt cagatataag
     1621 cattctccta ccttcattat tttcttcata aaaggctgta ggatgtattt gaatatattc
     1681 taaattttct atttttatat tatttcttaa agctattgca attccatcac ctgtaagatg
     1741 tctttgatta gtagaatttt taaaaagccc accaattcca cctgtagcta aaactactat
     1801 ttttgaaaaa acatgaatct cttttttaga tttaaaaatt ctagctccta tacatttatt
     1861 gccatctttt aatatatcta aaagataggc atcttctata agagttatat tttctctagt
     1921 tttagcttct tttaataaag ttttaaaaac aacttctcca gtattatcct tactatgaac
     1981 tattcgattt acactatgtg ctccttctct tgtgtaatct atctctccat tttctttgtc
     2041 taaaggcata ccatattcta ctatctgccc tacattttct atagattcat ctgcaagtac
     2101 ttgaactgct tcaactctat ttttatactg cccagccttc attgtatctt ctacaaagga
     2161 ttctatatca tcaatatttc tagcagttga aattccacct tgtgcaagat atgtattgtt
     2221 gttttcaatt gttgatttcg atactactag cacatttaaa cttttatcta aatttaatgc
     2281 acagtataat cctgaaactc cacttccaac tattaaaaca tcttgttcta aattcataag
     2341 tctatccctc tatccttctg ctaatttgtg catgttaagc agtgaattta aagccttttc
     2401 catgatttca tcttctacaa taacttcatt ttccatattt ttaagtgtac tatataaatt
     2461 ttctaatgtt gtctttttca tatctgtaca tagtattttt ccaccaggaa tataaaagtt
     2521 tttattagga ttatttttct ttaattcatg taatatacct tcttcagttg ctattataaa
     2581 gtctttgttt ttactattag tagcatattt tattattcct gatgtactac ctacataatc
     2641 tcctaaatct cttatttctt ttttacattc tggatgtact aatacttctg catttttata
     2701 cttatctttt aactcaatta tttcttcagc tcttatattg ttatggtatt tacaatatcc
     2761 gtcccaaaat ataaagtttt tatctggaaa ttgttctgca atatatcctc ctaaattttt
     2821 atctggaagg aatataattt ctttattatc tatgttttct agtattttaa ttgcactaga
     2881 agatgtaaca gaaacatcac aatgtgcctt aactttagct gtagagttta tataacatac
     2941 aaccaaagca tttggatact gttgttttaa ttttatcacg ccttcttcat ctaccatatc
     3001 tgccatagca cacccagcgt tacttactgg catcaataca gttttttcag gtgataatat
     3061 cttagcactt tctcccataa accttactcc acaaaataca accacttctt ctttacaatc
     3121 tctagcaatc tcacttaaat aatatgagtc accaactgca tctgctaatt cttgtatttc
     3181 tggtggttga taaaaatggg caagtattat tgcatttttt tctttcttta gctctttgat
     3241 ttgatatgtt aaatctttat ccataattgc accgctttct atatgtacta gtgtatatac
     3301 acctgtaaac tcattatatc acttgactat tctttcttca agaattttaa acctcttaat
     3361 attgttaaga tatagacatt tatattctca attgattttc cttttttctc catctattta
     3421 aactaatttt tatatttttt aatttttttg taaaatatta tcagaatttt gtttatattc
     3481 tttattgcta taacattgaa aatattacca aatacctgta tactaagtac atggttatgt
     3541 atatgtattt atttctgaaa ttatattagt tgtaatactt tatagaattt gtaggttgtc
     3601 cagaattaaa ttcaatataa atctacacat ttagataata tgtatacaaa gaccaaaaaa
     3661 ttttataaat ggggtgatat tatgacaaca ttcttaatcg gcttggctat attactaata
     3721 ggaggtgctt tatacggtgc ttattgtgaa aaagtatttg gcccagatga cagaaaaaca
     3781 cctgcacttg ctcaaagtga tggagtagac tatgtcccaa tgaaaaaatg gaaaaatagt
     3841 ctaattgagt tgcttaatat agctggtaca ggaccaattc taggacctat ccaaggtata
     3901 ttgtttggtc caatagcatt catactaata cctattggct gtgtatttgg aggagctttg
     3961 catgactata tgagtggaat gattagtata agagaaaaag gagcacaaat gccttctctt
     4021 atcagtagat ttttaggtaa taaagtattt caagtctata atatattcct ttgtctttta
     4081 atgcttttag ttggtgcagt ttttatttat acacctgggg atttagttgt tactcaaatt
     4141 ttaaatatga aatcgactat aaataatcca gttgtctgga tagtttatgg acttatcttt
     4201 ctatattact tgtgtgcaac actatttcca attgataaaa tcataggaaa ggtatatcca
     4261 atatttggag ctattctact tttatctgct gctggtgttg gaattggaat ctttacacaa
     4321 ggttatgatt tagctaattt aagtcttgca aattggaaag gtattcatcc tgatggtatt
     4381 cctcttattc ctacattctt tgttacagtt gcttgtggta ttgtttctgg attccactca
     4441 actcaagcta ctcttatagc aagatcagtt tcaaatgaaa aagaaggaaa aactactttt
     4501 tataatatga tgattttaga aggtttaatt gcaatgattt gggctgcagc tgctatgggt
     4561 atttacaata aaggaatacc taaggaatta gtaggttctc ctgatgtaat aggtttggtt
     4621 gcaagagatt tacttggttc tattggtggt atcatagcta taataggtgt aattgtttta
     4681 ccaataactt ctggagatac agctttaaga tctttaagat taatgcttgc agattacttt
     4741 cattatgacc aaaaggaaaa aaaacatcgt gttatattgt caatctgtat atttattcct
     4801 gtcatagcca tccttatatt tgcaaagctt agtgcttctg gatttaatat attgtggaga
     4861 tacttctctt ggagtaatca aactattgcc atatttgcat ttgcaatgat tacagtttac
     4921 cttataataa aagaaaagaa ttatattata agcttaattc ctggtatgtt ttattccttt
     4981 gttatattca gttatatatt taatgctcaa attggattta acttaaacat aaatatatca
     5041 tatgttttag ctgccatatt tactgtatta tatgctattt taactgtacg ctctggtaga
     5101 aagttaaaaa gcaaagcaga tactaagttg gctgactaaa tctaaataaa ataatactta
     5161 gaataaattt tattaaaaaa tgataaaaaa gtaggcaatc tcaagttaga tttgcctctt
     5221 ttttatttaa tacagtaata aatacttaag tatttactcc ttattggaat atttatccta
     5281 aatctctaat ataaataaat aaaagtttta aaataatcta ttcgtttata tacttaaaat
     5341 aaattttttg gaggaatact tatgaataat aaattacatg aacttgaaaa aaatctacca
     5401 gaaacatctt gttctttttg cacacatctt tcatttaagg ggcctagcct agactataga
     5461 tatgatatta gatgtgttat ttcagataca aagcccgatt ttagaggatg ttgtgaatat
     5521 tttgaaccag aatatacaga attaaataca ggagatttag acaatctata cataaacttt
     5581 cttgagacat gcctcaaggt aaattataat gattacatca attctatgta ttggaagtta
     5641 tttaaagaaa gaaccctact agaaaacaat tttaaatgtt ctatatgtgg atcaactgaa
     5701 aatgttgatg tgtatcatgt taataaaaat ttaggaaggg aaacttccaa agatgtagtt
     5761 gttaaatgtg ataaatgtaa ttgtaaataa gtgtataaaa tttagataac ttcacataat
     5821 aagtttaaat aaaacttagg aggttattta tgaaaaataa taatttaaat tgtgctgcta
     5881 ctaattgtgc ttataatact agtggatatt gttatgctgg tagtataaaa gtagatggaa
     5941 tgcaagcaac tactacagaa aatacttatt gtgcttcttt tgaagacaaa tatacatctg
     6001 gtataactag tcgttctaat gaaactaacc aagttgatac agataacatt cattgtgaag
     6061 ctgtaaaatg taaatacaat aaaaatgaac tttgcaaagc tgaaaaagtt catataaatg
     6121 aaagaaatgc aagttgtgaa acttttgaaa tgaaataaat ttctttttat ttagttttat
     6181 agtatttata caaagcaaaa ttgaacctat caaatagatg tctttattaa tgatgtctat
     6241 ttataggttc ttttttaaaa caattcataa tttatatata aaaataaatt attattttaa
     6301 tatattacct agaagtaaat ttaacaccca gaatatccat aaggaacata aatattggaa
     6361 ctccaattag taatccccat acacctaaat aatgctctcc tacaagtaaa ataataaaaa
     6421 caaaacaaac tggaagttta gttctattcg acatcaactt agggtttaat atgtatgttt
     6481 ctactgcatg cactatacaa atcataagta aaactccaaa aacctttgtt attcctcctg
     6541 tattaaatgc tattacagtt aatggaatca aagacactat aactcctgct actggaataa
     6601 gacccaacac aaaaatcata aatcctaaag cccatatttg agggaatccc atgaaaccta
     6661 agaaaatcat agaaacaaca gaatttataa aggcaatcat aacttgtact ttcattactt
     6721 caccaaaatt tttaacaaag ctctttccaa aaaatacaag cgaattataa ataaaagaaa
     6781 tcttactatc agaaagttta tctccaaaat ttttaatttc atttttttca agtaaaagga
     6841 gtaaactcag taaaaatgcc aataatatat ttactccaaa acttccaact tttgttgctg
     6901 ttgatgctat aagtagccct gcttgtgaaa tatatttatt aaaatccagc tttgagacaa
     6961 taggatacaa ttttggtcct aaagattgag caaattgatt tacatcaaaa tcactaaaaa
     7021 ccctactcaa ctctgtaagt tgaactataa ttattggtac aactgcatag ctaatcaata
     7081 ctaacaatat agcaaatagt gcatataaca ctataattat caatgaatct ggaatattta
     7141 aagaagaaaa cttcttaatt cgttttcttg tggctacaag caagttatag aaaataaaag
     7201 tcataataaa tgttaaaagc accatattta acatatacca aaatgtaatt agaataatta
     7261 ctacgacaga tatagaaaca attttatatt ttgaactgtc acgtgccaat cctttgttat
     7321 cttccatagt ttaaatcctc cccaaatttt tatgacttta taatgactgc cctttttatt
     7381 ttaatctcaa aaaacaagta gaaaaatact aaaaataact tattaatttt cataaaacaa
     7441 tattaaaatt tagagaagat acattttaaa taatcttact tatactgaaa tctgctctac
     7501 atcatatatt taatttatta ttatctatct catatagcaa ttcgtatatc tctggatatt
     7561 caaaaaacaa accctctttt agtaattgtc ttatttcatc tgtgcttacc cactttatat
     7621 cacttacttc ttcctcctgt aaaatagctt tggatatatc atattctttt ttaactaagt
     7681 atacatccca aagagtatct tcatgaatca tacttctaaa aactttcatc tcatctttag
     7741 ttatatctat ccctatttct tcctttgctt cgcgaattgc tccttctaaa ctgtcttccc
     7801 cagaaacaat acatccagtt gtcattcccc acatatttgg caatgtcttt ttacttttag
     7861 accttttctg aattaaaatt tgagagttac tatttaaaat ccacacttca actgccaaat
     7921 ggtaataacc ttcttcaata gaattacctc tttttataac atttcctgtt ttaattccat
     7981 cagcattata taaatcccat aattccattt caaaatctcc ttgactttac tataaattag
     8041 ataaactaca aatatatttt agcataatta attctgctca ttttttatta caatacttga
     8101 tttacattta tgttcattgc ttttcttttc cttccattct cttatatcat ctataataaa
     8161 tctatgtttc aacaattttg tgtcaaattt aaatattcta aacactattt gtaatacata
     8221 tcctaaacct aaagcactta caagcgtacc aatacctaca gaacctccta ataaccaccc
     8281 aacaactaat gctagtattt caagaattgt tctaacaaga cgtacagatt tattagtttt
     8341 tttctgaaga gcaatcataa gcccatctct cggtccactt cctaaacaaa cacctaagta
     8401 tagaaaactt gctatagctg ccaaaataat tcctataaca accataaaca cacctatata
     8461 agtgttgctt gcatgaggta tcactccaga aaatattact aaatcaataa aaattcctat
     8521 aaatgtcatg ttgagtaaag taccccatcc tatattttca ccaaaaactg catccaatat
     8581 aacaattaca actcctacca ttatagaagc ctgacctata gttatgccta gctttataga
     8641 taaaccttgg tgaagtacat cccaaggcat aagacctaca tgtgcattaa tcataagcac
     8701 agaagaaatt gcaaatataa aaaaacctga aaataatctt atcatacttt ttaaacttat
     8761 ttttcccatc aaaaatcact cctcataata ataataacaa taaataccaa taaaatatat
     8821 atataaatac gaaattttac agaattattt attaggttaa gataaaattt taattataaa
     8881 aagtggcaat ccaaatttta tacattttca cctatactct aagctttcgt gtataaaaaa
     8941 cggatatacc acttttttag tatataaaca tttttagttt ttcttattaa ttttcactat
     9001 aaattctagc ttcttcttct ccatttagta ctcttaaagt tccaaaagca agtgattcca
     9061 actcattttc tcctgccata atttctactg gtgctataaa ctcaactttc tttttaacca
     9121 ttgaagtaaa catttcagaa tatgcaattc cacctgttat aattatagca tctacctttc
     9181 catctactac agttgctaac tctccaatac cttttgctaa ctgataagcc attgcttcat
     9241 aaataatttt tgcttcttca tttccttctg ctatcatttt ttcaacttct ctagcatcta
     9301 cagtatttag gtatgaaact ataccacctt tacctcttat ctttttagtc atttctcttt
     9361 ctgaatattg acctgaataa caggcagcca ctaattttgt agcaggtact cttcctgacc
     9421 tttctggaga aaatggtcct tcatcatcag atagcatatc aaccattctt cctttttcat
     9481 gaagataaat acttactcct ccaccaatgt gagctactat taagtttaag ctcttataat
     9541 cttttccttt atccttagca tattttaaag ccattgctct agtatttaat gcatgccctg
     9601 cacttgatct atccattcca caaagtccag atattctcgc tacatctata agctcatcta
     9661 ctgcaacaga atcataaata tatgagttga ttccaagagg ttctgatatt gcatgtgcca
     9721 caacagcacc taaattggaa gcgtgttcaa gtactggtct atgtcttagt acatcaatca
     9781 tttcttcatt tactaaatat gctcctgatt ttactggtgg taaaactcca cctcttccta
     9841 ctattgcact aagagatttt aagtctatac tattttcttt aagaatattc aaaactgctt
     9901 ccttacgcat ttcaaactgg tcttgtatag tattatattt tgcaatctct tcagctggat
     9961 ggtctatcgt cttcacaaga atttgttctt ctccatcata tactgctatt tttgtagaag
    10021 tagaacctgg atttatggct aatattctgt aagtcataat tttcttcctt tcaccttaat
    10081 ttctatagtc tatttatatc tattataaac tatttgctaa ccatttccat accttcatgg
    10141 aaagctttta tgtttaattc aacaaatttt ggtttaacat tttcacttat aattttttcc
    10201 caatcaatag actctaattg catagattta actagacatc ctaataaaat aacattcatt
    10261 atttttgaat ttcctagttc ttcagcttta tcagctgcat ttataacttt tgcatttaat
    10321 ctacttaact ctgcatctat atcactttct tgatattcag ctcctccgat taaaacagtc
    10381 atagaatcta tcctatgatt atttactaaa gcttttcctt ctggttttaa ataattgaac
    10441 catcttaaag cttccatttt ttcaaaagat actaatatat ctgctccacc aatttctata
    10501 actggagaat gaacacaatc tccatatcta acttgtgagg aaactgaacc tcctctttga
    10561 ctcattccat gtatttcact catctttaca tcatatccag cttccatcaa tcccatagtt
    10621 aataatttac tagcaagtat agttccttga cctcctacac ctaccaaaag tatactctta
    10681 gtcatattat ttttcctcct taactattgc ttgttttgga caaacttgtg cacatactcc
    10741 acatcctaca cactgatttc tatctatatt tgataactta ttctctttat caaatgatag
    10801 agctggacat ccagttttca aacataattt acatcctata catttatcat ggtcaacttt
    10861 acacttagtc ttaaatggat tattaaattc ttctatatct tctttagaga attttttaag
    10921 tacacatggc catcttgtta ttattactga tggttcatct tctatagcta aagcccaatc
    10981 tagtgcttca tttacttctt ttaaattatt agggtttata actcttacat gttctattcc
    11041 acaagcttta actaatcctt ctatatcaac ttctttagtt ttagcacctt gtaaagtata
    11101 tcctgaacct gggttttctt ggtgacctgt cattccagtt attctattat ctaatataac
    11161 cgaaatagaa ttacctctat tgtaaacaac atctaaaagt ccatttattc ctgtatggaa
    11221 gaatgttgag tctccaagta cacctaccaa tcttttttca ttatcatcct tcatattaag
    11281 aactttttga gctccatgtg cagttccaaa agcagaaccc atacaaacaa catagtctat
    11341 tccattatat ggaggagcaa atccaagagt ataacaacct atatctccac caactattaa
    11401 attttttctc tttccaagtt catagaagaa tcctctatgt ggacatcctg cacagaaact
    11461 tggtggtctt ggtgttacta attcagattt gtattctata gtatcatttg tttttccaaa
    11521 tatagctttt cttaaaacat ctggtgtcat ttctccatat ggtggtatta catcttttcc
    11581 aatacaatct attccatatg cttttatttg ttcttctata aatgggtcat tttcttctat
    11641 aacatatatt ttatcaactt tttctgcaaa ttcttttatt ttttcataag gtaatggatt
    11701 tgtaaatcct agtttcatat atgatgcatt ttttccaaaa acttctttgg caaaattaca
    11761 acacatacca gatgctataa cacctatttt tgtatcattt atttcatagt agtttaaatc
    11821 agtttcattt gagaattttt taagaatttc cattctttct tcaacaacgc cccttcttat
    11881 ttgagcattt gctggaacag ttaccatttt cttagcattt ttaacatact ctttaatttc
    11941 aacttcttct ctatcatagc actccactaa tccttttgaa tgacaaagtc ttgttgtaac
    12001 tctatataaa actggtgtat cgtatttttc actaacttca aaagcttctt ttatcatatc
    12061 tttagcttct tgactagttg atggttcaaa taaaggtatc tttgcaaatt ttgcatacat
    12121 cctattgtct tgctcatttt gagatgaatg cattcccggc tcatctgctg taataagtac
    12181 cataccacca tttacccctg tatatgcata agtaaatatt ggatcagctg caacattcaa
    12241 accaacatgt ttcatagaag ccattgttct tgctcctgca attgaacccc ctatagcagc
    12301 ctcaagtgct accttttcgt ttggagccca ctctgcaact attgcatctt tatatgttgc
    12361 tatattttct aatatttctg tacttggagt ccctggatat gcagatgcat atttaacacc
    12421 agcctcatag gctccacgtg caattgcttc attacctgtc atcaattgtt tcatataaaa
    12481 ttccctccat ctacaattat taaattcata gtccacccaa tttgttcaat gaaattaatt
    12541 atttattttt acttctaaac tttcaagtgc ttcttttata atacttggtg ctttcttaca
    12601 tttatcttca gaaactgcac aaactgcaaa tcttaagccc atttttaatg gaactgcaaa
    12661 taaattatgt ttagtcaatt cttcacatac ttcttttgga ttatcacatg gtatacttac
    12721 aaagaaacct gctatatatg gaagaatttc taatcctact ctttcagctt cttttacaaa
    12781 tacatctgct cttctagtaa gcatgttttt gtatatttct ttttcatcct catattcttt
    12841 gaatttttta gggtcattta caatgttaga taatactgcc atagcacttc tattacaatt
    12901 tgaccaattt gctctacatg aatgaacaca tgagtaatgg aactcttcag ctacatcttc
    12961 acttgaagat atacaaatta tagctcccat tctcatacca taagctgtaa atccttttga
    13021 catactgaat ccaaccaata cgagaacgtt ttcaggcaaa ttagaaaatt tcttaaaaaa
    13081 ctttctacat acatcatcat cacctgcaaa gtcaatatat gctgaatcta cgaaaaatat
    13141 tatctttttg tctttatctt ttgcgacttc ttttgataag tctaatattt tatcccactc
    13201 atcatctgca acactatatc cagttggatt atgcgctggt gtgtttataa ttgtaaagac
    13261 tctaccttgt ttttctgcta tatttacaaa tttttcttta aacgactcaa aattaaacct
    13321 tctattttca tcaaaaagtt ggtaattaac tacttttcta ttagcctctt cagctatact
    13381 tacatatgga ctccagaacc aatcagatgt taatacctca tctccttcat tagtatagtt
    13441 ccatacagct aattttattg caccacttcc tcctggtgaa gctaatactc ttatatgtcc
    13501 ttctggtaag taatctctga aaaatacttt tttaactgct tctaagtaat ctggttgacc
    13561 ttcaagagct gcatatgcac ctatctcaca gttatctaat actttatatt cttcatatac
    13621 agttttcatt gttatcaatt ttcctgaatc atccattaga gcgcctattg ttgcatttat
    13681 tacattatcc ataccaaaag ccttctctgc tgcttgagct ctgccagata tgctaaatat
    13741 aacatcattt tcttttggcc acattgcatg cttaccaacc atactttgac tcataccatc
    13801 acccctaaaa ttgtatttac tcttacatta tatattaagc aattactatg ccaataaatc
    13861 ccactttatg taaaattgat tttgtttaga attattattt ttttcattat taaattaagt
    13921 gttttaacta tttttcttat aaatatatat gcctgtctaa aaaaataaaa atttgcaaaa
    13981 aagtaatgtt aatttttctt aacacttgtt ttaaaaaatt aacattactt caaaataatt
    14041 tatatgtaat tatatttaaa tatttttatt gtatttcttc cataaagatg tcctgcttat
    14101 tccaagaact tgtgcaactt catttttaga aagtccctga gcaaaaagca tacttattat
    14161 tttttcttca acatacttat ttacttcttt tatatctata cttatcttac catcatttat
    14221 cttacttata tttatagatt catcttggac ttctacactt gctgtcgttt cagaattaaa
    14281 tttgtctact tcagagttag gaagtaattt tttagtttta aaatctctat cttgtctcaa
    14341 tttaatttta cctgtcacaa catatttttg agctattgtc tttaactctc ttacatttcc
    14401 aggccagcta taattatata gcttatccat ttcatcttta gtcaaaacaa aattttcatc
    14461 tatactgttt attccattga gaccatcatc ctttaatact tcatttacaa aattgttaaa
    14521 caaaggtatt atatcttctc ttctgtctct taaaggaggt atatttatct ctaaactact
    14581 caatctataa aataagtctg ctctaaatgt acccataact attttttcgg ttaaagattc
    14641 attcgttgct gctataatcc ttatatccag aggtattata taatcagaac caattctcat
    14701 tatttgacgt tcctctatta ctcttaatag ttttgtctga atattaaagg atagactatt
    14761 tatttcatct aaaaaaagag tccctccatg agcaagttca aatagccctc tttttccacc
    14821 ctttctagca ccagtaaatg caccttcttc atagccaaaa agttcacttt caagtaaatt
    14881 ttctgctata gtagcacaat ttatggcaac aaaaggccta tcttttcttt tacttatatt
    14941 gtgtatacta tgagctataa tttctttacc agacccactt tctccataaa gtaaagttgt
    15001 ataatcactt tttccaattt ttttagcttc ttcaataaat tctttagtta atttatcttt
    15061 aaataaaaaa tcatcaaaag tatatctagc atagagacct ttttgattca agtcaaatct
    15121 tatttttctt tctaagtttt gtaacttggt tatatcttgt attattccta aaactccata
    15181 agtactatta tcaactttta tcaatgttgt cctagtatta acaattagat tatttatatt
    15241 tcttatcttt ctatcttcta cgtcctcttt ttcatgtaaa caatctaaca tccactccat
    15301 tttaggaaat acatctaaga tgtatttatt aagtgcacat tttctctcta ctttaagcat
    15361 gttttttgca ctttcattgt acaaaattat actgccatta ctatctatag caattactcc
    15421 atcttttata ccatcaagta tatttcgtaa cacttcatta ttaaactttt cttcacctaa
    15481 tgtatctaat aattttttac aatattctac agcttctctt atagattcat cactagcagt
    15541 tgcaaataca ctatcaattc catattgcct tgcaaaagaa catgccaaac ctcctcctac
    15601 gattacaact tcatcttttt ggtctatata ttttacaact ttacttctta tctcatactt
    15661 agattcaaac cattcttcag ttatttcagt acttatgaca tttctccagc caacatagtc
    15721 aaaagaaact tcattgtctc caagaatcaa tactactttt ttagaatatt tctttgctat
    15781 ttctattgct cttaaaaggt cagttgactt catattcatt ggtataacag gtacatttac
    15841 tgtatctatt actaaactat aacctccacc tctaccaatt atagcttggg cacctttttc
    15901 aacaagtata cgaccttgat tttccattaa gtctaggtta agtatgtcga ttattatagt
    15961 tccattttct acatcttctc tatataattc ttctattctt tcttttaatt caatatcaga
    16021 ggctataatt cctatttttt ttcgcaacaa aatcacctca attttaaatt ataatgtatt
    16081 gatttctacc tgcttttttt gatttatata ggttcttatc tgcatcttca attaatattt
    16141 caacatcttt tctactatga caccttttta tacttactcc agcacttata gttatatagt
    16201 tttttatttt agaatatata tgttcaatac cctcaaattc aagaagtttg aaaactcttt
    16261 taatatataa ttctatatta tcaatctctt caacaccgat tgattctata gaatctacta
    16321 atattaaaat ttcttctccc ccatatctga ttatgtgttc ggtaatatct ataaatacac
    16381 ttcttataat atcagttacc ttaactataa ctttatcccc tgctagatga ccataattat
    16441 cattataact tttaaaacaa tctatatcga ccagtattgc aaccatattt ttgtctctgg
    16501 ttccattaaa taaatccaac tgctgttcca aatatcttct attatatagt ttagtaagtc
    16561 catcttttaa aatatcattt tctaatttct tattatcatc cactagtaat cttaaactct
    16621 cttgtttttg tctgagttca tattgtttgt gaattgcttg agatgtttta taggaattat
    16681 ttttttccca cctatcagaa taccaatcca tacttttata atattctatt gccagtttaa
    16741 aatctttttt tagctcatat ccatttgcta ttagcccata aaatatagat atttttctaa
    16801 gattcaatga actcttttta actaaattta aaccttttat ataacaactt ataccttcat
    16861 ctatattacc aaattttata tataaatctc catacaactt atatatgtaa tctagtttag
    16921 aattatatat aaaaacatct ccaaaacttt tatatatatt ttttgataaa attaaatagg
    16981 tgtttacctt ttcaaaacta caattatctt tctttaactc aatttcagct gaatataaaa
    17041 atataaatgg atataaataa tccttatata caccttcaac aactttcatt aattttatag
    17101 tctttaataa aataacttct gcttctttat tcatatcttc ttttaaatat gcccatataa
    17161 ggtctatttt tatagacact ctttcagtta ctgatattga gttattactg tgtgcaacat
    17221 ctaatacatt atttatgtat tttatagctt ctacattatt tccactctct aaataacaca
    17281 aacttattat acatttacaa aaagcctcta tagagtataa attattttct tgagccaatt
    17341 ttagacattc aattaagtat tccatacttt ttataaagtt attaaataaa tatagataaa
    17401 ctctcccaaa tatataattt gccctactta caagagcttt attttttaaa gttttaaaaa
    17461 aagacacttc ttctactaaa gctattacat ccgttttggt ctgatataaa gcacttattt
    17521 ctacacataa actcatattt aacaatacca acaactcatt taaatgattt tgtcttataa
    17581 ttttttttgc tgagaaataa aaattattta ccttatcata ttttcttata gaaatagctg
    17641 ataaagtaag ataaatataa attttagata ttatatctga atcatctttt aatgacaatt
    17701 ttttaatata ctttaatgac tctatcaaat agttgtatga tgcttctcta tcttttttta
    17761 tatagtttat aagactaatt aaatataaag tatagactct actattatct tctaattttg
    17821 tatttaaaag gtctttgtga taatccaaga tgtagtttaa atctgtcaaa tttagataga
    17881 atttagtcaa catatcgtat tctatcttgt ttatatttct ctttaaatct tctattaaac
    17941 tccttttcaa gtaaatcacc aatcctattt caacagttaa aaattcttaa aatcatgata
    18001 atgcaaacat ctatttctac cactttcctt tgctttatat aaagctttat cagcattttc
    18061 aattatttct tttatatcta tactactatt tttacatgta tcaatgccaa tactaactgt
    18121 caaattattg tttaaaaatt tctttacaat cctacataat tttcttccaa atattttact
    18181 ttttttataa tctttacata cagataatat cagaaattct tctccaccat accttatcat
    18241 aagcatgtct ttttttagat atttttttat tattatagtt atatttttaa gagcaatatc
    18301 tccattgtag tgtccataag tatcattgta ttctttaaag taatctacat ctatcataaa
    18361 tgctgtgcaa tattcactaa cttcttgttt ttctaaaaaa tcgttcaaaa aagttctatt
    18421 atatgcactt gtcaaatggt caacatactt ttttttatct aaatcaagtt ttacttttct
    18481 catgttattt atttcttttt ctatatactc atgtctataa tttaaggaat ctatataatt
    18541 tctatttcga gcttttatat acatcatttt taactcataa tacattttaa agtatttcat
    18601 actcatttca taattttgaa tcttttcaaa acacaaatat atactcttat atgctaactt
    18661 cacataatta taatttttag catttttaga tttttcaagg agttttttat ttgtgtttaa
    18721 ggcattgtca taatatccaa agatataata tatctttgcc tggtgataaa ttatttctaa
    18781 atcatatatt atatattctt ctatattttt tatcatattt aatatgtttt tagctctatc
    18841 taaatagcat attgattgtt caaaagattt ttcattactt tttgcataat acatggctaa
    18901 acttataaat aaatcaaact tctctacttc ttttaagcta tgatttttaa ttttttctag
    18961 atatacttca gattttgcta aattatttat tgcgacagga taatttctag tctttattaa
    19021 tattttagtt atgttgtttg atgctctata tttttgaatt atatttacat ttctatactt
    19081 tttattgctt attacttcat tgaaatattc catggaacat tcataatttt caaacgaaca
    19141 ttcacactca cctatcttta tattacatag tgaagatact tgcatatcct ttagtaaatc
    19201 tgcatatttt cttgctttta aaaaatttac cttagcaatt agagcatcat ccaaaaacaa
    19261 aaaatatatt ttaccaataa taaaaaaata tattttttta caattaaaat cgttaatttc
    19321 ttttatcttt atatacaacg tttctatctc tttaattatt acagaagatt ctatacactt
    19381 acttgcctta atgtaaataa gttgtgattt aaaaataatt tcttcaatta gaaaattatt
    19441 ttcatcacaa ataagattaa atttatccat atataaattt gccttattta catcttcatt
    19501 ttttaaactt aaaatagcta tttgtgaata aaatcgtgct aaaaatttat aatctttggg
    19561 taagcattta tcaatatatt tacaggaaat caaaatatac tctttcattt tttcactaaa
    19621 cccttgaata ccatataata aagctagcaa aaaatttgat tttaataaca ttaaactatt
    19681 ttgttcagtt ttatagcaat caattaaatt ctttactaca tcaattttat tttcaataaa
    19741 atcgttatta gtcaataatc tttcattcaa ggttagttta aacattgaat ctaaaattgt
    19801 atcatctatc tcttccaaat atttactata tattgtaact cacctccgac ttacattatc
    19861 tcataaattt agtaattttc catactattt ttgaaaaaag ttgatgtctc aatttagaaa
    19921 tttctcttaa attaagacat actttacact aaactataca attttctatc tgaactatat
    19981 aatcctgaca attttcgcaa attatcacac ttacaatata actattatca actttatttg
    20041 cccttgatag tttattaaaa gatagtcctt tataatcaac agatatattg cttattacat
    20101 attctccatc tttactgaaa atataaaagt gatattctaa aaaaggaaag aattttttct
    20161 tttcttttac tccttctaaa cataatggac atgcttcttg ataatattct acatcaaaat
    20221 caacttcttc tgcttcatta agtatatcaa ttatttttga aatacttact ccttgaactg
    20281 gattttcttc atcatttatt aaagcactac agttctcctc ttttaataaa tattccttat
    20341 catcatatat aaacttatat aaactcatat tatatcctcc ttataattat taatctccaa
    20401 gttattctac catttaaata aagttaataa aagtaattgt ttataatctt tataattaag
    20461 ttatgtatac atatattcct atgcgctatc ttaattaatg attttaaaat ccaagtttgc
    20521 aatttgaaca tccagtttcc caaaatctat tgtcaaaact cactttagtt attaatataa
    20581 tgatataaat atataactgc atagatgtta cacacttaac tatttaatat gatacgattt
    20641 ggtatctaaa tttatatatt gtatataggg ggagatatat atgtataaag ataaaagtga
    20701 tgaatgtata cacttaatga ctgcatacat cgatagtata agtggatatt attcatttat
    20761 tgacacacaa ttagaggatt ttatgatgaa atatggtgaa aacattgttg attcaaattt
    20821 acacagtata atgatgttgc tttgtaaatg gggattatct tagcatttca agaaactttt
    20881 ttgtatattg tatcctatat tatttattca ttaacaaaaa agattgacat aaacttaaaa
    20941 gctatatata gatttcttta aaaatctata tatagctttt ttaatttttt caaaatgtat
    21001 acttaaataa gttagttttt ttcaaaattt gactgtctaa tatgatataa tttaactatc
    21061 tacaacaata aaaaatatct aatatgtatt atctagttta gctcatcata ataacatcca
    21121 tatatttaca attaagatat tttcaatata gtaatactca attttaatat tataaaaagg
    21181 agagattttg tatgaattac aatgacttac taaaatcagc tagagagaac tttaatggaa
    21241 catgtaaggt atgtaaaatt tgtaatggat tagcttgtgc tggagatgtt cctggtatgg
    21301 gtggtaaagg aagtggttcg tctttcattg aaaatagaaa aagtctagaa aaaataaaga
    21361 taaatatgag agtcatacat aatgtttcaa agccagatac atccatagaa ttatttggta
    21421 gaaaaatgag ttctcctata ttcgctgcac ctgtatcagg tactatattg aacatgggtg
    21481 gtaaagtttc cgaaaaagaa tacatagagc ctgttgttag aggttgttct aattctggaa
    21541 tttatgctat ggttggcgat actaatgtag atactttttt actggataat ttagatgtat
    21601 tgaaggataa taggggaaat ggaattgtat ttataaagcc ttggaataat tcaaagataa
    21661 tagaaaaaat tagattgtct gaagaagcag gtgcttttgc agttggtgta gaccttgatg
    21721 cttgtggact tattaataat caatttcaag aaaatccttt ttctcctaaa acaattgatg
    21781 agattagaga attggttgaa tccactagat taccttttat tataaaagga attatgactg
    21841 tagatgatgc tttgatggct gtagagtctg gtgctagtgc cattattgtt tcaaatcatg
    21901 gtggaagagt acttgattat actcctggta cttgtgaggt acttccagat atagctaagt
    21961 ctgtaaaggg aaagataaca atacttgttg atggtggagt taggactggt gttgatgtag
    22021 ttaagatgct tggattgggt gctgatgctg ttttgatggg aagacctttt gttactgctt
    22081 cttttggcgg tggtcttgat ggtgtggagt tttttataga gaagattagg aatgagttat
    22141 gtgagactat gattttgact ggttgtcaaa atgttaagga tatagatggt agagttatat
    22201 ggaatttatt gtaaaatatt tctagactct aagatactga ttaatatatt ctatataaaa
    22261 aggttgtcgc cctatttctt agtgcgacaa cctcttttct aataacgctc tccggcagct
    22321 tgccaagtgg cttttccaac aacaccatct tttgttacac caagtcttcc ttgaagtatt
    22381 tttacttgat tatatgtagc aggtccaaat ttactatctg gatcaatatc agaaccattt
    22441 atttgttgac ataaaagttg tactaaatgc acaggattcc ctttttctac atgtccatat
    22501 cctactacag tggtatttat atttacgcta taacttatag gaccagtaac atcaaaacga
    22561 tttaaatctt ttttatatct aataataaat gcttttggtt caatattata atcatctata
    22621 ttaatattat atgaatctat aaatttttca ttaataaaga ttgtatcatc tttagatgga
    22681 tttatattta attctttaca ttttttttca taatcagatt ttataggttg tggtgcattc
    22741 tcataaataa attcataacc agttattgta aatgaatttg ttgtttgctc ttcattactt
    22801 tttgatacat ttacatcatt attagtactt gcaaatacta aactagtaga tattagagtc
    22861 aaacaccctg tgactattaa aattttcttt agacttttca tttcaaaatt cctcctaatt
    22921 tgttaataaa ttataatact ataaaaatct attaatttac aactctcatg ctaatatcat
    22981 cttcttcctt aagatctgcg cctgtttttt ctaaaatccc tatatttctt aaataatttg
    23041 aattatcaaa actaatactt tcaaaattaa aatatgtaac tgaaaataat gtaaacaaaa
    23101 tcaataacat caatattcca cttttccctt ttttcttaat aatactatca agtctctttt
    23161 ccaaatttgt cttattaaat tcagttgtta aaataccact attataattc ttactaagtt
    23221 taattgactt tataagtgct aacgcatatg ctttcttatc ttttaaagag caatcagtca
    23281 aaacactttc atcacaacat aattcacaat ctagatttac tttattgctc attatataaa
    23341 caagtggatt aaaccaatac attattttaa cagacaaaac taaaaacttt atcaaaatat
    23401 ctttgttttt aaaatgcatt aattcatgtt tcaaaatcca agttaactca tctttactat
    23461 aagtatagtc tggtaagaat atgtacgatt taaataatcc catacctgct ggacttatca
    23521 attcatcaga accccttaac tcaattttct tttttatgtc taattctttt aacaaatttt
    23581 tatagataca atttacatca ttatcttcaa tatcataaga tacatcaaca acgagatttt
    23641 taaattttgt gtattctata aatgtataaa ctgcaatggc tatagttaca aataaccata
    23701 aataaactaa atacagcata aaatcattat ctatagaaat atcaatttgt gtaatattat
    23761 ttcctactgt attttctttg ggatctttta cttcatacat tactgtataa ttaaatagaa
    23821 aaagtaacat tctaaagact attaccaacc aaatataata attaaatctc ttactaaacc
    23881 tcttaaaaaa atatattttc aaaaataata atagacaaat accaaaacta catacaatag
    23941 ttgtctttat aagattgtca aaaacatata gcatataatt attcattctt taaattatca
    24001 aaataacttt ctaaaaaatc tagcgtgtct ttacctatat tttcatcatc atgcaatgct
    24061 gaaattaagc ttttcaaaga atcatcatgt atattactta ggaaatcctt tgtctcaaaa
    24121 cttaaataat ctttgtgttt tactattact gtgtaatgtg tatatctgtc tattttttga
    24181 gcatctaaga atcctctttt tactaaccta gataaaagtg ttagtgtagt ggtttgtttc
    24241 caaccatatt tttgttccat aacttcaata acatcttttg atgtcactgt agcatctact
    24301 ttccaaataa atttcattac ttttagttct gcttgtggta tttttcttat catcatttac
    24361 acctccctca aaactcttgc tactttaagt ctacaatatg taaatttttt agtcaaacgc
    24421 tttatgaaaa aatgtgaatt tttgtacttt ttattaattt tctaattttt ttaaatatta
    24481 aaagttagat tttaaaatat agttattcaa gtattttgct ttttacgtat ttaattataa
    24541 tagtgtagaa tgttatttcc acattaaaat tatttaacaa aactacctat atttttacac
    24601 aaggaatatt ataatacttt tatttaaata aactagagta atatctaata aattttaaca
    24661 atctcctaat tgtacctttg tgttattaaa atatctgttt tatataagtt tatgttataa
    24721 gtaaaattat acatatcaaa taaaggtata aaaacaccat tttgagtgtc tttaaaataa
    24781 agtttgtatt cttctaaaaa gttataataa ttaaaacatc actactatac aaaggaagat
    24841 gtacactttt tatgtttaat aaaaactaaa atattaaaaa aatttattga agaatatgat
    24901 gtcaaaacaa ttacagatat tcaagatata ctaaaagatt tattttaaag tacaatccat
    24961 taaatgttag aagcggagct tgatgaactt ttaggttatg atagaacgat aataagaaca
    25021 aaaatactaa aaactctaga aatggatata gaaataaaaa tattaaatca gattttggag
    25081 aaataacttt aaatatttca agaaagcgaa atgaagattt tgaactaaag gtaattagaa
    25141 actatgaaaa tgatatatta ggaataaaaa atcaagtgat tggaatatac ttaaaaggca
    25201 tgtctactca aaatatatta agtcatctta aaagtactta tggaattgat attatctcat
    25261 tcactaataa ctaaaactac tgataaagtt attcctttag ctcataaatg gtaacttaga
    25321 cctcttaata taatttattc aattgtattt atagatgcta tacattataa agttagaagt
    25381 gaggtggaat aataaacaaa acagtatata tagctatatg tattaactta gaaggcataa
    25441 aaggggtttt aataatatga aatagtacaa tcaatataca atagtattaa gaggttggtg
    25501 aaacaattgg aatgaattag taacatattt taagtatcct caagaaataa atacatcgat
    25561 atatactaca aattcaatgt aaagttagaa tagattatta agaaaagtta ctaaattgaa
    25621 atctattttt actttggata attatttgca cacatcacta tacttaacaa ccatgtatat
    25681 ttcttaaaaa tggactcaga aaattagaaa ttgtgctcaa attttagctc atttaagtat
    25741 ttattttgaa gaaagaaatt tttcaaaata aacaagaatt tttcttaaag ggttaatagt
    25801 ttttgcaaaa atgaaaaata tatcaaaata aggctatgat ttttaaagcc atagccctat
    25861 tagtaaaaat ttaattatca cttaaaaaat aaatttttgt ttaaagaata catgtaaatg
    25921 tttacagatt cagcaattta aaattatctg tgcaatagct ttctttttaa agacgtcttc
    25981 cagctgcatc ccaagtactt cttccaacaa ttccatctct tgttaatcca agtcttcctt
    26041 gaagtgactt aactgcatta tatgtagcag gtccaaattc actatcatca tcaatacttg
    26101 aaccatctaa ggttctacat aaaagttgaa ctaaatgcac aggattacct gattcaacac
    26161 gattatatcc gactacagta ttacttacat ttaatgtata actcttaggt ccagtaactt
    26221 caaaaacata acctttttta tatctaataa tatatgcttt tggctcaaca tagttttcta
    26281 catcatttgc atctatagaa tctttgttaa caaaaattat atcattttta gatggtttta
    26341 tatttagcgc ttcacatttt ttttcataat caaattttac agattgtggt gcgttttcat
    26401 atgtaaattc ataaccagtt atagtacatg aacttattat tgaatcatca tcctttgatg
    26461 tatctacatc agtagtagta tttgcaaata ccaaactagt agatattaga gttagacaac
    26521 ctgtaattat taaaattttt tttaaatttt tcatttcata attcctccta atttattaat
    26581 aatatgacaa tatacctttt cattacatat attaatctat taatttataa ctctcatgct
    26641 aatatcatct tcttccttaa gatctactcc tgatttttgt aaaatcccca tattccttaa
    26701 agaatttgaa ttatcaaaac taatactttc aaaattaaaa tatgtaactg aaaataatgt
    26761 aatcaaaatc aataacacca atattccact tttacctttt ttcttaacaa tactgtcaag
    26821 tctcttttcc aaacttgtct tattaaactc tgttgttaaa ataccactat tataattctt
    26881 actaagttta attgacttta taagtgctaa tgcatactcc ttcttattct ttaaagaaca
    26941 atcaatcaaa acactttcat cacagcataa ttcacaatct agatttactt tattgctcat
    27001 tacatataca agtggattaa accaatatat tattctaaca gacaaaacta aaaactttat
    27061 taaaatatct ttatttttaa aatgcattaa ttcatgtttc aaaatccaag ttagttcatc
    27121 tttactataa ggatagtctg gtaagaatat gtaagattta aataatccca tgcctgctgg
    27181 acttaccaat tcatcagaac ctcttaattc aattttcttt tttatattta attcttttaa
    27241 caagtttttg tagatacagt ttatatcatt atcttcaata tcataagata catcaacaac
    27301 tagattttta aatcttgtat actttataaa tgtataaact gcaatgacta tagttacaaa
    27361 taaccataaa taagctacat acagcataag attattatct gtagaaatat caatttgtgt
    27421 aatattattt cttactgcat tttctttggg ttcttttact tcatatacta ttgtataatt
    27481 aaatagaaaa agtaacattc taaagactat tatcaaccaa atataataat tgaatctctt
    27541 actaaacttc ttaaataaat atcttttcaa aaataataat agacaaatac caagactaca
    27601 tacaatagtt gtctttataa gattttcaaa aacatatagc atataattat tcatccttta
    27661 aattatcaaa ataactttct agaaaatcta gcttatcttt acctatattt tcatcatcat
    27721 gtaatgctga aattaagctt cttaaagagt catcatgtat attacttagg aaatcctttg
    27781 tctcaaaact taaataatct ttgtgtttta ctcttattgt gtaatgtgta tatctgtcta
    27841 ttttttgagc atctaagaat cctcttttta ccagcctaga taaaagtgtc agtgtggtgg
    27901 tttgtttcca gccatatttt tgttccatag cttcaataac atcttttgat gtcactgtaa
    27961 catctacttt ccaaatgaat ttcattactt ttagttctgc ttgtggtatt tttcttatca
    28021 ttatttacac ctccctcaaa actcctgcta ccttaattct acaacatgtg aattttttag
    28081 tcaaacactt tatgaaaaaa atgtgaattt ttgtactttt tgttaaattt ctaatttttt
    28141 tacaatatta aaagttagat tttaaaatat atctatttaa atattttact ttttacatat
    28201 ttaattacaa tagtgtagaa tgttatttac acattaaaac tgtttaataa aaattcctat
    28261 attttcacac aaggaatatt ataatacttt tttttaaaat aaactagagt aatatctaat
    28321 aaattttaat aaccttctaa ttatgccttt atgctattaa aacatctatt ttatactgat
    28381 tatttacaaa tatatctaaa ttaattataa attttattga ataagacttt tataattata
    28441 cctttcataa attataaaaa agcactttta taaaaaatgt gcttttaata tctactaata
    28501 aagttct
//
LOCUS       DAEOTL010000047        27653 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEOTL010000047 DAEOTL010000000
VERSION     DAEOTL010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27653
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.047"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            160..1311
                     /locus_tag="KRH82_002409"
     CDS             160..1311
                     /locus_tag="KRH82_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8655682.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRNHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNDFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            1429..2067
                     /locus_tag="KRH82_002410"
     CDS             1429..2067
                     /locus_tag="KRH82_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBG8655683.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            2068..3090
                     /locus_tag="KRH82_002411"
     CDS             2068..3090
                     /locus_tag="KRH82_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBG8655684.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            3080..3700
                     /locus_tag="KRH82_002412"
     CDS             3080..3700
                     /locus_tag="KRH82_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655685.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDIKMNDYMENCNM
                     MAGLALDKIGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(3824..4510)
                     /locus_tag="KRH82_002413"
     CDS             complement(3824..4510)
                     /locus_tag="KRH82_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBG8655686.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKEYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(4524..5069)
                     /locus_tag="KRH82_002414"
     CDS             complement(4524..5069)
                     /locus_tag="KRH82_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655687.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            5297..6544
                     /locus_tag="KRH82_002415"
     CDS             5297..6544
                     /locus_tag="KRH82_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBG8655688.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            6631..8625
                     /locus_tag="KRH82_002416"
     CDS             6631..8625
                     /locus_tag="KRH82_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBG8655689.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            8625..9947
                     /locus_tag="KRH82_002417"
     CDS             8625..9947
                     /locus_tag="KRH82_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBG8655690.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNLEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            10226..11512
                     /locus_tag="KRH82_002418"
     CDS             10226..11512
                     /locus_tag="KRH82_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBG8655691.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            11598..12905
                     /gene="grdB"
                     /locus_tag="KRH82_002419"
     CDS             11598..12905
                     /gene="grdB"
                     /locus_tag="KRH82_002419"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:12645..12647,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBG8655692.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDGAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     DEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            13193..13924
                     /locus_tag="KRH82_002420"
     CDS             13193..13924
                     /locus_tag="KRH82_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655693.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLEDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            13926..15284
                     /locus_tag="KRH82_002421"
     CDS             13926..15284
                     /locus_tag="KRH82_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBG8655694.1"
                     /translation="MINLFSSDLFLKYSFLFSFIVYRILMVIVQYYFLISFTNVNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTRGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            15323..15808
                     /locus_tag="KRH82_002422"
     CDS             15323..15808
                     /locus_tag="KRH82_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655695.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QRKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(16071..16307)
                     /locus_tag="KRH82_002423"
     CDS             complement(16071..16307)
                     /locus_tag="KRH82_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655696.1"
                     /translation="MLLTHIYFNGQFKQTIELYKQAFNATVKTLIEDSCYLLIVHNEI
                     VIHNKFLILNDFGNKNGVSISEGYQPTYKIQTAS"
     gene            complement(16462..16686)
                     /locus_tag="KRH82_002424"
     CDS             complement(16462..16686)
                     /locus_tag="KRH82_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBG8655697.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(16783..18036)
                     /locus_tag="KRH82_002425"
     CDS             complement(16783..18036)
                     /locus_tag="KRH82_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBG8655698.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLNNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            18296..19285
                     /locus_tag="KRH82_002426"
     CDS             18296..19285
                     /locus_tag="KRH82_002426"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBG8655699.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            19357..20097
                     /locus_tag="KRH82_002427"
     CDS             19357..20097
                     /locus_tag="KRH82_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBG8655700.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            20313..21464
                     /locus_tag="KRH82_002428"
     CDS             20313..21464
                     /locus_tag="KRH82_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBG8655701.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            21489..22244
                     /locus_tag="KRH82_002429"
     CDS             21489..22244
                     /locus_tag="KRH82_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBG8655702.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNNNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            22436..24823
                     /locus_tag="KRH82_002430"
     CDS             22436..24823
                     /locus_tag="KRH82_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBG8655703.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNSNI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(25054..25287)
                     /locus_tag="KRH82_002431"
     CDS             complement(25054..25287)
                     /locus_tag="KRH82_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBG8655704.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            25576..26166
                     /locus_tag="KRH82_002432"
     CDS             25576..26166
                     /locus_tag="KRH82_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8655705.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            26280..27125
                     /locus_tag="KRH82_002433"
     CDS             26280..27125
                     /locus_tag="KRH82_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655706.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFGVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKLKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTAECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            27122..>27653
                     /locus_tag="KRH82_002434"
     CDS             27122..>27653
                     /locus_tag="KRH82_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655707.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IVIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLILASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLY"
BASE COUNT        11051 a         2879 c         4627 g         9096 t
ORIGIN      
        1 aagtttaact ataaattagg tttatatttt ataaaaattt gctaaaaaaa acaattaaaa
       61 attgtaaaga aaaaagatat aattagaact gtagtaataa atgttttatt atagataata
      121 gagttttaag tatcttaaat aatatttgga ggaatatgaa tggaattaag accaagaagt
      181 gcaaaattag aagaatttga taaagtaata gaattaataa actatgtatt tagaatatca
      241 agaaatcata aaccaactat gatggaagaa tttcctcttt tactaagtaa aaataatata
      301 gaaaatatga ttataatatc agaagatgat aaagtggttt ctgatgtaaa ctatctaatt
      361 caggatgtat ctattcaagg aaacagattg aaggttgcag ctataggtgg agtatgtact
      421 catccagatt atgaaaagag aggctattca tctaagatat tggataaagt agaagaaaaa
      481 atgttttatg atggtgtaga tattgtaatt atatcaggaa caagaagtct atacagtaga
      541 agaaattgta gtttggtaaa gagtttttat aaatatacaa taaaacctga agatgtaaaa
      601 atagcatatg aaatagttga atttgatgaa actaattttg aaaaagataa tgatttagat
      661 aaaatgattg aactatataa tcaaaatagt actagattta taagaacgag agatgagttt
      721 caaaaactat tgcatgcagc aactattgcc tggggaccaa ttggttacaa gaaggtattt
      781 ataaaggaaa ataataatat aataggatat ttgataataa gaacaataaa aaaagaagat
      841 tctactgtag gagaagttgc tgaaataggg ttaaactctg taaatgttga aaatatattg
      901 aaatatgttg caaataaatt tggattagaa tatttaaatt ataaagtaca tgtgaaaaat
      961 cttaaagacc agttgaaatg taatgggaca aaatctttgg attatcaaca aggaactatg
     1021 aaaataataa attttactaa gttgtgtgat agtttaagaa gttattttag tcaatatgta
     1081 gattttgaat tactaaaata catggaattt aaacaagttg aaaataaata tattattaaa
     1141 tacaaagaag aagaacttgt aatagaaaat ttggataagc ttaataaact gttttttgaa
     1201 aaaaatgagg aacagtacaa tgactttaaa catctaaaaa atatatatga atttgctaca
     1261 aaggcatttc ctgtagattt tccatggact gcaaatttaa attatcaata gttttagatg
     1321 atattaaata aaattgattg atacctagag ttagtccttg ttaaataaga gaaattattg
     1381 gatattgaaa aagcaatttt gtaagtaatt agaaaggatg agtattatat ggacatactt
     1441 gatgatatag cagaatgtat attaaatatg ggtgtagata atatagagaa tttagtaaaa
     1501 attgctatag ataaaaatat tgatgtggaa gatatttatg aatatggttt aaacaaaggt
     1561 atgataggag ctttagataa gtttgagaat aaggaatact atctttcaga agttatagta
     1621 tgcacagatg cattaaataa aggtattaat cttttgaagg gaactggaaa agtaaagaaa
     1681 aaatcaaagg gagtaattct gatgtctgta gtagaaggag atactcatga gataggaaaa
     1741 aatattgtaa aagtaatggt agaagccact ggatataagg ttattgactt aggtgtaaat
     1801 agaaaaagtg aagatataat agaagaagct ataaaaaaca atgtagatat aataggctta
     1861 tcttcaatga tgacaactac aatggaaaat atgaaatcgg ttatagacga acttaatatg
     1921 attgagatag ataaaagacc aaaagtaata attggtggag gacctgtaag tatggagttt
     1981 gcagaagaaa taggagcaga tggatacagt tcaaatgctc caaaagcagt taaattaata
     2041 aataaactta taggaggtga agtttaaatg ttttcagata tgactttact tcagtatata
     2101 aatagtgaag atagaggttt ttttctgcct gatatgggta caaatggatt gttcttaata
     2161 aataaaaagg catatgaagt atatgatagt gtagatttgc aattagaatt agcaaagact
     2221 atggacaagt attttgaatc agattttata tactcattct gtgatgggat tacattttgt
     2281 gaaactctgg gtttagagac attaagacca gattatgatt ttccaagtgt attgacacat
     2341 actataactg acagagataa attaagaaaa ttagatgttc cagaccctta tacgagtgga
     2401 cgtatgccac tcaatataga gagcttatca gttatatcaa aaagtattaa aaaaccacta
     2461 tatgaatcga tacaaggtcc atttacactt gcaggtcaat tagctggagc tactcaactt
     2521 ttaagatgta taataactga taaaaaattt gtagaagaat tattggaatt tacaactgaa
     2581 ttggtaagaa gatatgctgt agctgcaaat aaagcaggag caaaatatat ttcaatagca
     2641 gagccaacat cagtaaccct aagtaaagat agatttgatg aatttatagt aaaaaattta
     2701 aataaaatct acaatgaact tgattgttgg aaaggtatgc atatatgtgg agacaccaga
     2761 gaattattag ataatatgct aagttgtaat atagatgcag taagtttaga ccaaatttta
     2821 gactatgaag aaattgctcc aatgattcct agagatatag ttttgattgg taatttagac
     2881 ccaataaaac ttcttggacg ttctaagcca gataagatta gaagagagac actaaaattg
     2941 ttaaagaaga tgagaggata tgataacttt ttatgtgatt ttggctgtaa ctgcttaaat
     3001 accactccag tagaaaattt acaagcagct ataaaggcag gaagaattag ttataaagaa
     3061 ttagatagga ttgatattga tgaattataa tagtaataaa aataaatatc ttttaaagga
     3121 tataaattta gatgatattt ttatagataa gaatattgtg ctaaagtttt tggggtatgg
     3181 aaatagaaaa gctccagata caattagtaa aatcgttgaa agagaaataa gaaatataaa
     3241 tgatatttta gatatcaaga tatatataag tgaagttgat attaataaaa cacctaaaga
     3301 atgtaaaaaa gcatttgctg tactatatac aataggggat aaaattgata ttaagatgaa
     3361 tgactatatg gaaaattgca atatgatggc agggctagca ttggataaaa taggtatagt
     3421 atgtttagat tgtattaatg agaaaataaa aatgtattta aaaggaaagt atgatagtct
     3481 caaaatatcg catgaaatat atccaggaga taaagatttt gaagtagaga gacaaaagga
     3541 tatttataac tatgtaaaaa ataaatataa tagtatagaa atagaaatca atgattatca
     3601 tcaactatcc cccataaaaa gtgttgcaat gcttatttta atgggggatg aagaaaattt
     3661 agaatcaaga tgtagcaaat gtcctagaaa atgcttttaa ctagttttca agactaagat
     3721 ttgttttgtg tatgaattgc aataattttt ttggtcattt tatgtataaa ctaaaaaaat
     3781 tattgcaaag taatattcta tttaatttga acagacttac aaactatagt agtttcttta
     3841 attcaataag tgtatttatt tcataagttg gtatatgatt agtataattt atactgttat
     3901 tggaatttaa ccaacaagta tctattcctg aatttattcc acctaagaca tcagaggtta
     3961 agctatcccc aatcattaag gcagaagatt tatcatgaca attaaacttt ttgagagcgt
     4021 atttaaatat ttcaggattt ggttttgata ttttcaactc ttcagataca accattccat
     4081 caatatattc ttttattttt gaattttcaa gtcttttctt ttgaactgca gaaattccat
     4141 ttgttattat aacaatagta tacttttttt taagatattg taatatatcg attgcacctg
     4201 gaattaaaaa tgtacattca cctaaaaaat ttaagtacat tttgctaaga gtttcagaat
     4261 caacatccaa agatatttta tttgcaaaaa gttcaaatct aagtaattta agttcattca
     4321 aagttataat atttttttca aggtcgagcc aaagcttatc acttatattt ctatatgact
     4381 ctatataatt ctcaaaatta aattctaaat caaactcaga tagaagtttt ttaaaagcat
     4441 gtgattcact tttcttaaaa tcaaataaag tatcatctgc atcaaaaaat ataaatttat
     4501 atgtcttcat ggtttttact cctttacaag atgactgcaa aaattacttt actttcacta
     4561 tttgagtcat tttgccattt atgttttgtt cctaaaggaa cttttacact atctcctttg
     4621 gacaaagtaa attcatcatc atccataaaa agtttaactt ctccctccaa aacatatgca
     4681 atttcatctc cattatgagt aatcctatca acacaagaag aagtgtttgg agctaaatcc
     4741 ataattgcaa attctaaatt accactagag tctggaatta aaatctcata tataacttct
     4801 ttgcttccag gtaaaataac tttttttcta ttatcatgtc ttactatcaa gtttttttta
     4861 tctacttcag atacaaaaaa tgtaaataaa ggaacattta gagaagaggc tatagatttt
     4921 aatgaattta cagatggatt agcaagacct cgttctattt ggctcaataa tgatggtgta
     4981 acatcagcta gttttgctaa atctcgaata cttaagtttt gtttttttcg aacttcagct
     5041 attttttccc ctaaatttaa atcattcata taaatatcct ctctttttaa tttaaaaaat
     5101 attaacttaa aataatcaag taaaatgatt atgtagtatg aaattattat aacatataga
     5161 attaggtttt gaaaaaacta tgttcaatat aattaaataa attaaaatat aattgacaaa
     5221 gtggatacag aatacttaaa atatatttaa ataaaattaa gcaaaagata gttaatttat
     5281 gataggaggg gatattatgc aaataacgac ttttggagct atatttggtt tattaatagc
     5341 aattatttta attataaaaa aatttcaagc tgtatatagt ttaatgttag gagcatttat
     5401 tggaggatta gttggaggag caaatataac acaaactgta gattttatgg caaatggagc
     5461 tatgaatata tcaccatcaa ttcttagagc tttggcatca ggtgtattag ctggaagttt
     5521 aataaaaaca ggggcagtag ataaaatatc agaacagatt gtaaaaatat ttggtgaaaa
     5581 gagggcttta ttttcgattg ccatttcaac tatggtactt gctggagtag gcgtaaattt
     5641 ggatgtatct ataataactg tagcacctat aggattatat ataggtagaa aattaaatta
     5701 ttctaaattg tcaatactat tagctatgtt gggagggggt aaagcaggta atataatatc
     5761 accaaatcca aatactatag cagtagcaga taatttttct gtcaatctct ctagtgttat
     5821 gatggcaaat ataattccag caattattgg agttgttatt acagttattt tagcaagtat
     5881 attaataaat aaaggaaata aagtacaatc atatgaaatt ttagagcaaa gagaagattt
     5941 accaagttta tttaaatcat tatgtggtcc aattatagct atatttctat tgtttttagg
     6001 aaatgtatct cctatagtta tagacccaat gatagccctt ccaataggag gaatcgtaac
     6061 tctaattgtc acaggaaact tgaacaattc aagagaatat ttagcttttg gattatctaa
     6121 gatgcaaggg gtatgcatat tattacttgg aacagggact atcgcaggaa ttatacagat
     6181 gtctgaatta caacagagta caataggtgc tttacaattt ttaaatatgc cacaattttt
     6241 attggcacca gtttcgggta tacttatgtc attagcaaca gcatcatcaa cagctggtgc
     6301 tactatagca tcatctactt ttcatgatgc tataataaat ggtgggctat caccgatttc
     6361 aggtgcatca atagtaaatg ctgggtctag tgtattcgag caattaccgc atggctcact
     6421 atttcatact agttcaggta gtataaacat ggatataggt gaaagattta agttaattcc
     6481 atatgaagca ttgataggaa tagtaatgac tataatttca acatctattc aattagtttt
     6541 ataataaata taaatattta atgaaaaaag taggattttg ttattaaata ttgaatttat
     6601 tatagtaaaa aagaagattg gagttttaaa gtgaataaaa aaaagattgt tattataggg
     6661 attatttatt catttttagt agtattttca cttacaaata tgtatgtaaa tatggagtat
     6721 aatttaaatg tatttgaata tattaagaag tcacttccat ttacagaaga agaaaaaaag
     6781 tggttagaaa aacacaagaa tttgatttac agctctgacc aaagttcacc tcctttgaga
     6841 tataaaggta aggaagatgg acagtataag ggaattattg ttgatttaat aaattctctg
     6901 tcaattcaaa ttggtagaga tttttatttt aaaccaaata attggtggaa agaatctttc
     6961 gtaaattcaa tagatgatag tataaagttt tttgacttga ttccatcaaa agaaagggca
     7021 aataaattta tatttactga cccaatatac actttgagtg caaatatatt gaaagataaa
     7081 aagtcccagg atataaatag ttacatggat ttaaagggga aaacagtagc aattccagaa
     7141 ggtgattatt ctataaattt tttaaagcaa aaaattcaag atataaacat tttattgact
     7201 ccagatataa agactggagt caaccattta atgtctggaa aagtagacgc agttgttggt
     7261 gatgaaccag tattgcgata ctatataaat aattatggac tttcaaataa atacagtgtt
     7321 ttaagtaatc ctatatatac taaaaaagca gttcttgctg tacctaaaca atatgaagag
     7381 ctggttagta ttttaaataa aggcattttt aaacttcaga aaaatggagt gtataaagat
     7441 ttaaagaaaa aatggtattc tacgtataat gaagttgatg atatattgta tgagcgagga
     7501 attgtgccta gtatttatct ttttataggt ataattttaa tatcaattta tgttttttat
     7561 agctatacat atttgttaaa gatagaaatc aaaaggaaaa cagaacaggt aatagaaaat
     7621 aaaaaaactt tagaggcaac ttttaatagt attacagata taataatgct tgtagatgaa
     7681 aataacaata tagtagaatc gaacaaagta ctatatgact ttatgggtga aatgagttat
     7741 aagatagcag atttgattag catgataaaa ggtgttattg aaaatacctt ctctgaaaat
     7801 actaataaaa ctagtgaaat agaaatacac aataaaattt taaagataaa cacttttcct
     7861 gtagagtata aaaaaaataa tactgagtat atagtagttc ttattaaaga tataactaat
     7921 gataaaatag tagaggcgaa attacttaga gaaaacaaaa tgatatctat aggacaatta
     7981 gcttctgggg tagcacatga gataagaaat cctttgggta taataagaaa taattgctat
     8041 ctcttaaaag ataacgttac aatggaagaa gtaaatgatt gtgttaaatc aatagaaagt
     8101 aatgtagata gagcaagtaa tataataacc aacttgttaa atttcgcaag aatatcagat
     8161 gataatttag aacatataaa tataagaaat tttattgaaa atatagtgaa acttcaatat
     8221 aaaatgttac agttaaagaa tgttgaaata aaaattgact gtgaacataa tttaatatgc
     8281 tatataaatg gagaatcgtt aaaacatgta tttataaatt taatttctaa ttcaatagat
     8341 gcaatacatc aagatggaaa aattattata tactgttatg aaaaaaatca ttgtttattt
     8401 atagatttta aagataatgg tgaaggaata aaagaagatg ccctaaagga catatttaat
     8461 cccttctata caacaaaacc aattggtgag ggaactggtt taggtttata cattacttat
     8521 aatgagatta aaaagaataa tggagatata agtgttgaaa gtaaattggg ggttggaact
     8581 tgttttcata taaaaattcc attaaataaa gaggtgacta tataatgaaa atactattag
     8641 ttgatgatga gctagaatat ggagtggtaa tgaaaaaaat tctacaaaag aagggctatc
     8701 ttgtagatat agcactaagt ggtgaagaag ctataaatat aattaaaaaa gataaaaatt
     8761 atgatttggt tttatctgat gttatgatga aaaatatgga tggagtacag ctattagata
     8821 gaattaaatc tattaataga gatatagagg ttatattagt tacaggatat ggaagtattg
     8881 aaaatgcagt tgatgctatg aaaagaggag ctttatctta ttttataaaa agtaatccca
     8941 ttgaaaattt attagaagaa gttgaaaagg taaaggcaag taaaatatct gtttctgtac
     9001 aaaaaaataa tttggaattt actttggaat ctaaaaatag agattttaat aatatcataa
     9061 aaatagcaaa aaaagctgct tgtaaagatg ttaatatatt aatcttggga gaatctggtg
     9121 taggaaaaga tatattagct agatatatac atagcataag tccaagaaag aatgagatat
     9181 ttgtacctgt aaattgttgt tctttttcag aaaatctatt ggagtctgag ttgtttggtc
     9241 atgaaaaagg ttcttttaca ggagcagtag atagtagaaa aggtagattt gaactttcga
     9301 ataaaggaac tctatttttg gatgaaatag gagatatacc tctaaatgtt caggtaaaac
     9361 ttttgaggac acttgaggac aaatctatag agaggatagg aagtaataaa tctattaaag
     9421 ttgactttag gttaatttgt gctatgaata aagaaccaaa agtggaaata tcaaatggaa
     9481 atataagaga agattttttt tatagaataa gtacaataac aataactata ccaccgctaa
     9541 gaaagagaag agaagactta actactctta tagaattttt cttaaataag taccaaattg
     9601 aacatgataa aaagatacac tcgattgata aggaagtaaa ggatttttta ttaaattaca
     9661 attatccagg aaatataaga gaattaaaaa atataataaa tagacttgta gttttaagtg
     9721 aagaaggcaa tttatcaaaa gacaatttaa atttaatatc aaataatgta tacatagatg
     9781 ataaaataag tattagacct ttaagagaaa taagaaaaga gtttgaatgt gagtatattg
     9841 aaaaagtttt atctttgtgt ggaaataata tttcaaatac agctaaaaaa ttggagatta
     9901 gtagaagaca gttaaccaat aaaatatcag agtataatat taagtgagaa aaaaacttct
     9961 cattaagtga gaaaaaaatt tctcaaactg tattaaaaga taaacagaaa aaatctgttt
    10021 atcttttttt attataattt taaaaattaa tatttacaat aattattggt aaattcaata
    10081 ttggtgtaaa ttaaaaatga aaatttctat gacattaata catagaatat atattttaaa
    10141 taattggcat agaaaatgct ttatatatta ataaacgtaa taaatacttt taattgcgat
    10201 taaatatatt aagggggatt ttcatatgaa gctagagcta gggaatatat ttataaaaaa
    10261 tgttgaattt ggagaaaaga cagaagtaaa agatggagta ctatatatta gtagcgaaga
    10321 aatagaaaag atagtattag aagatgaaag gattgtaagt gtaaatgttg aacttgcaag
    10381 acctggcgaa tcaataagaa tagctccagt taaagatgta atagagccta gagttaaaat
    10441 tggagatgaa agcaaaatat ttcctggaat tataaataaa gtgaagactg taggaagtgg
    10501 aagaacccat gtacttttag gagcttgtgt tgtaacttgt ggaaatatag ttggatttca
    10561 agaaggcgta attgatatga gtggtcctac tgctaaatat acaccttttt caaaaacaaa
    10621 taatatatgt attgttataa aagcaaagga tggtatagat actcatgatt atgaagaagc
    10681 agctagaatt gcaggattaa aaataggtgc atatgtaggt gaggcaggaa gagaagttga
    10741 gccagatgaa gtcattgtat atgagacaaa gccattatta aaacaagtaa aagaatatcc
    10801 agacctgcca acagtagcat atgttcacat gttacaatca caaggacttt tacatgacac
    10861 ttattactat ggggtggatg ctaaacagat agtgcctaca tttatgtatc caactgaaat
    10921 aatggacgga gctataatat ctggaaactg tgtagcacca tgtgataagg ttacaacatt
    10981 ccatcattta aataatccag ttatacatga cttatataaa agacatggaa aagatttaaa
    11041 ctttatagga gttattttga ctaatgagaa cgtattctta gtcgataaag agagaagctc
    11101 tgatatggta gctaaattaa tagaattttt aggagttgat ggagttctag tgacagaaga
    11161 aggttatggg aatccagata ctgacctaat gatgaattgt agaaaatgta gtgaagttgg
    11221 agcaaatgta gttttgataa cggatgaatt tcctggaaaa gatggcaaga gtcaatctat
    11281 agcagacgct actaaggaag cagatgcagt tgtttcttgt ggtcaaggaa atctagtggt
    11341 tcatttccca gcaatggaaa aaattatagg aactttagat tatgttgaaa tgatgatagg
    11401 tgggtataaa ggatgcttaa atgaagacgg aagcatggat gcagagctac aaattataat
    11461 agcatcaact atagcaaatg gctataatca tttgacagca agatattatt aaataagtat
    11521 ttgaatataa agttctgttg atgtaatcat tggtctaact gatgtaataa ctataaagtg
    11581 atttggagga ttaagagatg agtaaaatca gagtggttca ttatataaac aatttctttg
    11641 ctggtatagg tggagaggaa aaagcagata ttccgccaga aaaaagggct ggtgtagtag
    11701 gacctggaat agcatttcag agtcaattta atgatggtgc agagataatc tcaactgtaa
    11761 tttgcggaga tacgtatttt ggtgaaaata ttgagagtgc aactcaagaa cttttaaaaa
    11821 tgataaaaga agaaagccct gatttattta ttgcaggccc agcatttaat gcaggtagat
    11881 atggagtagc ttgtgggact atttgtaagg cagttgaaga agagttaaat attcctgtaa
    11941 ttacaggcat gtataaagaa aatccaggtg tagatatgtt taaattagat ttgcatatag
    12001 tgtctacagg aaattcagca gcaagtctta gaaaggtagt tccaataatg acgaaactag
    12061 gtcttaaatt ggttagagat gaggaaatag gacctcctga agaggaagga tatataatga
    12121 gaggaataag aaaaaatttc ttccatgaac ttagagggtc tgaaagagca attgatatgt
    12181 tggttaaaaa gatgaaaggg gaaagctttg aaactgagta tccaatgcct gaatttgata
    12241 gagttacacc tatgaaacct gttaaagatt tatctaagat aaaacttgcc ctagtaactt
    12301 ctggagggat agttccaatt gataatccag acaaaattga atcttcaagt gctactaaat
    12361 atggaattta cgatttaaca gatatggatt ctatgtcaaa taaagaattt acaactatac
    12421 atggggggta tgatagagca tatgtccttg aaaatccaaa tttagttgta ccactagatg
    12481 tagttagaga gcttgaaaaa gaaggtgtaa ttggagaatt agtagattat tttataacta
    12541 ctacaggaac aggaacgagt gttggcaatt ctaagagatt tggagaagag ttttctaaaa
    12601 aattgttaga agatgatgta gatgctgtaa ttttaacttc tacatgaggt acttgtactc
    12661 gttgtggagc aacgatggta aaagagattg agagagctgg tatagcagtt gttcatatat
    12721 gtacagtagt accaatatca cttacaatag gagctaatag aattgttcca gcagtaggga
    12781 taccatatcc acttggaaat cctatgttag gagaagagga aagtaaaaaa attagaaaga
    12841 atatagtttt aaaagcttta aatgcactaa cagaagatat agaagaacaa acagtatttg
    12901 aataataaaa atacaacaca acactgaaat aaaaaaagat atcaaaaaat aattttttaa
    12961 aattatttta cgatatcttt ttttattagg taaattcgaa agttgcatat tatttgcata
    13021 tttttaaatt aaatttataa aagtgataaa ttagtttatt ataatattga tacacaaatt
    13081 caaattagat atactatgaa aagtgagatt attacatttt ggaacaaata ttcaacatat
    13141 taaaccagat taattgaaca gaaaaaatta actttatata ataattagaa taatgataag
    13201 aaagaaggtg tatatattga tttcaattgc catttgtgat gatgaatcct atatgctaaa
    13261 tcatttaaag gaaaatatag aattatacat gaagcagaag aatttattat ataatataga
    13321 gctttttaat aaagtagaag atttactatg caatcatgaa aagtttaata ttgtattttt
    13381 agatatacag atggaagaga ttaacggaat gcaggcagct agaaaattaa ggtcatatgg
    13441 taatgagtgc tttataattt tcgttacagt tttaaatgaa tttgtatttg atgcttttga
    13501 agtagatgct ataaattatt tgataaaacc tctatctaat gagaaactat ataaaacttt
    13561 ggataaaata gttacaaaac tcgaggataa tgaaagtaat tatatcacaa tacaaaaagg
    13621 ttattcatat tggaaattaa aacttgctga tattttatat tgtgaagtta taaaaagaaa
    13681 gatttatgtt catttaaaga aagagactgt agattattat gagactattg aaaatttaga
    13741 gagaagttta ccaacaaatt tttttaggtg tcatcgtagt tatataatca atttacaata
    13801 tgtatatgga tatgaaaatg gtaatgcagt tatggaaagt ggagatagaa tacctgtttc
    13861 tagactacgt caacaaatat tttcaaaagt tatgcttgag ttcatgaaaa ataggaggat
    13921 ataagatgat taatttattt tcttccgatt tatttttaaa gtacagtttt ttattttctt
    13981 ttattgtata tagaatttta atggtaatag tgcaatacta ttttctaatc agttttacaa
    14041 atgttaattc aaaattttgg tgttttattt tatattcgat aatttcaatt tttttaatca
    14101 ttataaatac atattttaat ttatataatt tattttcttc acagattcta ttttttctta
    14161 tgactttttt atttgtaaag tacataataa aacaatctac tgttttatct atagtatcaa
    14221 ctttgttagt atatttaatt gaacaattag tatatggatt tacagctcca ttaaattact
    14281 tgatatttac tagtgatata aatacagata tttataaatt tgatataaat atgggactat
    14341 cttctttaat tactattata atagctggat ttatatattg gtatagttct aaaaagttta
    14401 atattaaggt catgaacttt gataaatata tagcaatttt gatgattcca ttgttgctta
    14461 taatattatt tatgcaatca tttgaatata gttcaaatat aaatatagat acaagtcttg
    14521 ggattgtaaa gctgctatta aatacttcta taactgaaga aattcaagct tttctttttt
    14581 ctataattgg aactatatgt gtattttttt ctctatttac ctttaagaaa ctaattcaag
    14641 ctctcgaaga tgacaaggag agggcaatta tgaatcaaca gattcatgct caaaaaaact
    14701 atattgaaga agcgaaatca cgattatcac aaactatatc ctttagacat gattttaata
    14761 atcatttagc tattgtcaat ggattgttga aaaaagacca aattttaaaa gcacaagatt
    14821 atttaaataa gcttgaaaaa gtaacaagtg acctatcatt ttcttgtaat acacagaata
    14881 ttgttattga tgctcttttc aacaataaat taagtatagc aaaacaatta ggcatagagg
    14941 tagattgtga agtaattata ccccaaagca ctaacatgaa cgattttgac ctatgtatag
    15001 tgtttgctaa tgctattgac aatgcaatta aagcttgtag agttgtagat aaacaaaata
    15061 ggtatttaaa gctttccact aagttagaag gtggattttt tatgatagaa ataaaaaata
    15121 gctataatcc aataaataat tatacacgtg gttcaggtat aggtctttta aatataaaag
    15181 aaattgctaa aaaatatcaa ggggctataa gtatagataa gacatcagat tattttcaaa
    15241 taaatgtatt gctggttatt tcattacatt gcgctagtat ttgagaacaa tttcattgaa
    15301 aatagtattt gtaagctata ttatgtattt gaatagagaa agtttgatat atagaaatga
    15361 ggaggttact aaaatgaaag ttggaaatat aaatggtcaa gcaccaatta caaatggttt
    15421 agatagttgt caaagtgagg tacaaggctt agaacaaagg aaaaaatcat tacaggatga
    15481 aatagagaaa gtaagaagtg ataaaagtat tgatggtgaa acagccaaat taaaaataga
    15541 agctttaaaa aaagaaatgg aagagattga aaataaaatt caagagttaa aaggaaataa
    15601 agcaaaaaaa acaaataaag aagaaaataa tgtttcagaa gtaaataata atctattaga
    15661 gagaaaaaaa gaaccttcta ataatgaaaa tgtaaaacaa ctatatgatg tttttgaaag
    15721 aagcaatgta gacgaacaat gggataatac ttatcgtgtt ctccaagatg ataaaaactt
    15781 aaaagtaaaa tttaatagac ctatatagtt tatttataaa aatagttaat attttaatta
    15841 tcaccacttt ttagaagaat acacacttta ttttaaagac ccacatattt atttacagtt
    15901 agcacattta tatgtggttt tataactatt atttacaagt ctatattgat aacttttaca
    15961 tagtatataa tgtttaaata cttattcaat tttatctata cataaacaaa aaaagagatt
    16021 ttaaaatctc tttttagatt gttgacttat ggctttttga tttaataaaa tcaagaagcc
    16081 gtttgaattt tatatgttgg ttgataccct tctgatattg aaacaccatt tttgtttcca
    16141 aaatcgttta aaattaagaa cttattatga atgactattt cattatgaac aataagcaga
    16201 taacatgaat cttcaatcaa tgttttaaca gtagcattaa atgcttgctt atacagttct
    16261 atcgtttgtt tgaactgtcc attaaagtaa atatgagtca ataacataac tatatctaca
    16321 taaattaata taaatttttt atactgtaca ttatctaact gttgattatc tgtattacaa
    16381 catgattgaa tttaaaaagc catcaacaca tagaatgttg atggcctgaa aatagattta
    16441 aaatctcttt tttattatat attaattatt ttttaaattt atattttttg catcagattt
    16501 tctaatagct aagtcaaacc ctctaaatct aatcactata gggtcattaa gaggagctat
    16561 ctttttcact tcaacttcag tgccatctat tagtcctaag gctagaagtc tcttcataag
    16621 tttttcattt ccagctatat tgtctataat tcccttttgt ccaagtttta agttgtaaac
    16681 agtcattatt aacacctcct aatgaaaatc attatcaaac tttatattta taatatataa
    16741 caaaaagagc aaattgtcaa tatataacaa aaaataaaca tactaagtta gtatgtttat
    16801 aaaaaatagt atacatggga tactaatagc atctagcaaa aaaccactta ctaatggtac
    16861 aaccaaaaag gcttttggag aatcaccata tttttgtgtc aaagaactca tatttgccaa
    16921 agcgttcgga gtagctccta ttccatgtcc aatcaaacca cttattatga tggcagaatc
    16981 aaaatctttt ccaagtactc taaagcaaat aaatattgaa aataggatta taaagattac
    17041 ttgaaaagtt actattaaga gaataggagg taataatgta gataattcaa ataaatctat
    17101 attcataagt gataaagtta aaaaaattcc caatgaaagt tcttttaaaa aatctataag
    17161 tttaaaattt aattctagta tatttatctt atcatttaaa tttctaaaaa taacagccga
    17221 aaacatacaa gttacaacag agggtaatag tatattaaac gttatataga agcatctact
    17281 tataatttct cctgtattta tacaaataaa tatgagaaga acctgttcca aaaatacaga
    17341 tggtgttatt gtttcggaga agttattatt ttttatccta ttcttatttc taaaaaattt
    17401 acttccaaat ctctttagat ttctattata tctaggaatc gacaagtcta tatttgatga
    17461 tggttttaat ttatatttat ttattagaaa tttagctaca ggacatccca atataccacc
    17521 cataataagt cctattgttg cagcagataa tccaacccca actgctcctt ctataccgag
    17581 attttctatt gtaagtccaa atgcagcaga ataaccatga ccaccttcca tagatacatt
    17641 tccacacata agccctaaaa gaggttcaag ttttataatc tttgatattg taatagctaa
    17701 tatattttga caaaatgcca atactccaca caaaatccaa tatctaaata atacactacc
    17761 ccctttcttt ataagattta tgcttatttc gagtcctata gttgtaaaaa agaaagttat
    17821 aaaatttggc attaaatttc cacttataga tatatctgct atattaaaat atttaaaaaa
    17881 taaatttaga aaacaaaata atagacctcc tattactggt gcaggtatac agaaattatt
    17941 taaaaagtta actttattat tcaataaatt accaattaaa aagaagaata tagatagtgt
    18001 caaggtttgc actatatcaa aacttaaggt aatcaaaata agtcctcctt tgtaattcaa
    18061 agttttaatt atataactta aattcttatg tattgaaatt ttattatcaa atgtatatta
    18121 ataaatgtat attaaaaaga atcagtagat ataattagat agtcataaat taaattaaaa
    18181 tattttaatg agatatgact tttttagaat taaaaaccgt agtatattga tataatagaa
    18241 ataagactta aaaatctgtt gatagtatta tttataagta cagtaggagg ataaaatgtt
    18301 tgaaaattta cctaagatag atttacattg ccacttagat ggaagtgtta gagtagaaac
    18361 catgcttgat atagctatta aagagaaaat agatttacct tcaaataata tggatgaaat
    18421 aaaaaaatta gcaaaggttt cttttaattg tacttcacta gatgaatatt tagaaaaatt
    18481 tgatttaccc ttaaaagtaa tgcaatctaa ggaaaattta aaaagaatta cttttgaact
    18541 tttggaagat gcaagtagag aaaatgtaaa atatattgaa attagatttg caccattact
    18601 tcacacccaa aaaggtatga gtgttaaaaa tataattgag ggtataattg aaggaattag
    18661 agaagctgaa agtatttatg atataaaagg caatttaata ttaggttgta tgagaacaat
    18721 gacctcaaaa gaggcattat tagtaattga agaagggaaa tcatttgtaa ataaaggtgt
    18781 tgtagcagta gacttgtgtg gtccagagaa agagggattt tgtaaggaat ataaagatgt
    18841 ttttaaatta gcaagagaat atggatataa agttacaata catgcaggag aagctgcaag
    18901 tggagaaaat gtattggatg ctataaatat tttaaaggcg gataggattg gtcatggggt
    18961 aaaaattaaa gaccataaaa aggcgtataa tttagttaaa gataaaaaaa tattgcttga
    19021 attatgtcca actagtaatg tacaaactaa gacagtagat tcttatgagg tacatccatt
    19081 ttatactttt tataaagata atttacatgt aagtataaat actgataata gaactgtatc
    19141 agatataaat ttaagttcag aactaaatgt tatatttgat acttttaaac taggattaga
    19201 agactataaa ataatttata gaaatgcagt agaagctagt tttgcagata aagaaactaa
    19261 agagtatttg aatagtttaa tttaatagat aaaaatattt aaactttaaa ttaagctatt
    19321 aaattgacaa aaatacattg tattaggaga aaaaatgtga aagattatga agatgttgtt
    19381 tatattaaac tagtcaaaaa agaacttgaa gaatggaaga aaaatatatt aaagaaacct
    19441 tctatatttg acaaagcatc aaagggtata cagaataaat ttaatggagt attgccagat
    19501 aaatatcatg aaataattac ttcttctata aaagtaatga caaaaaccgt actgtttgga
    19561 tataaatatg ctacaaagcc accacttaga aatatgtcat tagaagaaag agaaaaatta
    19621 gttttagaaa aagctaaaac ttacaagact acagcaatga ttgaaggggc aggaacaggg
    19681 gcaggaggaa tcctcttagg tttatctgat tttcctttgc ttttaggtat taaagtgaaa
    19741 tttttatatg atgtagcttc aatatatgga tatgatgtta aagattatag agaaaggatt
    19801 tatatattaa atatattaca gttggctttt tctagtcaac agcatataaa caaaactttt
    19861 aaattgatga ataactggga tgaatatgta aatagtctac cagaagacat caatgatttt
    19921 gattggagaa catttcaaca agagtatagg gattatttag atttagctaa gtttttacaa
    19981 ctaatgcctg gaataggagc atttgtagga ttttatgtga atggaaaatt aattgataaa
    20041 ttatgtgaaa ctgctgtgtc tgcttataga ttgaggattc gagagcttaa gttataagaa
    20101 aaattataac ataaaaaatt agttatacaa tatatctata tgtatctaat tttgcattga
    20161 taaaaacaat tatggataaa aggtaaagca tgatagaatc taatgtagag gtttgtattt
    20221 taatggaaaa atttagtttt tattgcttaa gatacaaatt gaattacgaa gagattgaat
    20281 tatgaagaga agtaattggg aggaatattt tcatgacaaa tttgccaaaa caatttgata
    20341 gcttcaatga agctagacaa aaaggattta taaatgcaaa ggaacttaag gaaagtggga
    20401 aaaagatggt tggagttttc tgtacattta ctccagttga aattccaatg gcagctggag
    20461 caactgtagt aggtgtatgc ggtgttagtg aagagccaat acctgatgca gaaagggtgc
    20521 ttccaagaaa tctttgtcct ttaattaaat caagctatgg acatgcaata acagatacct
    20581 gtccttattt ctatttttct gatttgttga taggagaaac cacttgtgat ggtaagaaaa
    20641 aaatgtatga agaacttgca aaagttaagc caacatatgt aatgcatttg ccaaatactt
    20701 caaaaggaga atttgcctat aaactttgga aagatgaaat gataagatta aaagaagagg
    20761 ttgagaaatc tttaggtgta actataactg aagaagatat aagaactgct ataaaagata
    20821 aaaatgaaga aagagaactt ttaaaagagt tttatgcact tggtaaatta caaccatctg
    20881 cacttacagg ccttgagtta cataatgttt tatatcaagc aggttttaaa tttgaccgtg
    20941 cagaacttaa acattcttta agaaaagtta tagatgatat gaaagaaaga tatgaaaaag
    21001 gtgaatgtcc tgttcaaaaa gataagccaa gaatattgat aacaggttct cctattggtg
    21061 gaataagcga aaaaatagtt aaaactttag aagatgcagg ggcatcagtc gttgcatatg
    21121 aactttgtgg agctattaga tcaaacgatt tattggttga tgaagaaata gaagatgtat
    21181 atgatgcttt aacacaaaaa tatataaata taggttgttc ttgtatgatg aataatgaca
    21241 atcgtattga attattagat agaataatag atgaatataa tgtagatgct gtaatagatg
    21301 tagttttaca agcatgtcat acatttaata tagaaagtta tagaataaga gaatttgtta
    21361 caaaagaaaa aaataagcca tttatgtctc ttgaaactga ttattcaaaa tcagatactg
    21421 aacaattaag aactagattt gaagcgtttg tagagatgtt gtaggaataa ataaaagtag
    21481 gaggaactat gtttagtata ggagttgact cagggtcagt ggcaacaaag ggtgtgctat
    21541 ttgatggtga aaaaattatt aagaaaataa ttataccaac tggatggagc cctaaaagta
    21601 catctaaaca ggtctatgag ttgctaagta gtgaaattga caaaaaagat ataaaaaagg
    21661 tggtaggtac aggttatgga aggggagtaa tggattttgc tgataagaaa gtaacagaaa
    21721 taacttgtca tactagaggt atttactttt taaacaataa cataaggact attttagatg
    21781 taggtggtca agatagtaaa gttataaatt tagatagaga tggaaatgta tttaacttta
    21841 taatgaatga taagtgtgct gcaggaactg gtcgattttt agagattact tctaaccttt
    21901 taggaagcga tattgaaagt atagatacat tagctaaagg atatgaacca gttaatatat
    21961 ctagtatgtg tacagttttt gctgagtctg aaattgtaag tcttctagct caaaacattt
    22021 ctactggaga ggtagcagca gggatactta aatctattgc aaataaatcc acctcaatgt
    22081 tagcaagagg tgaggtaata gatgaagttg catttactgg agggcttgca aaaagtaaag
    22141 aactagtaaa aatgatagaa gaaatactgg gtaaaaaaat ttttattgca gaagatactc
    22201 aaataatagg agctttagga gctgctgtaa taggatttag ataaaaacat ataaaaagaa
    22261 aatgagaagc tgaatttatt ataaataaat tcagtttttt attttatttt atttatttat
    22321 aaaggaaaac tttggtataa ttgatttaaa tgattgtata tttgtaaata cttgatattt
    22381 agtcatatat aacattataa ttttaaaaat tagctcaaaa taagggggag aaagcgtgaa
    22441 aaaatttact tcaaaaaaag taacaaggtt tgttgcgctg tttttaatat ctattttagt
    22501 catgtcaaca attcctgtat cagctgacaa tagcaataca ttgaatcaga taaaaaaagc
    22561 agaatacagt gagacgtata aacaatatct aaatgatgct aaaaatggac gtacagaaaa
    22621 atataatggg attataccaa atccatatca gttggaaggt actcaaatcc aaagtaaagg
    22681 aagaacagct ccaacatctt atgaccctag aaaattaggt cttatgacat caataaaaaa
    22741 tcaagaggat ttaggaatct gttgggattt tgctgcaatg gcaaccttag aaagtttctt
    22801 aaagttaaat aattatggag actatgattt atcagaagaa cacttaagat ggtgggcttc
    22861 agatggtgaa tatggatggt ctgtaaatga tatgaatggt gctttaaatt atgaagctat
    22921 gggatattta acatcttggt caggtcctaa attagaaaaa gatatcccat acaatggtag
    22981 agtatctaaa gcacaaggag caaaaaaacc aactaatatg aatacagcac ctactgtttt
    23041 taatgtgaca gatgctgtgt gtgtaagcaa tgacataaat tctacaaaaa atgctatatt
    23101 acagtatgga gctgtaacat ctggttatta tgaagatatt aaatatcaaa gtgatgacca
    23161 aaattcatat tattgtccaa caaaaagttt taatacaaat catgctattt caattgtagg
    23221 ttgggatgat aactattcta aagataattt taattcaaat attagaccat caaaaaatgg
    23281 tgcttggtta ataaaaaata gctggggaga ttataattct gagggtggat atttctggat
    23341 atcttatgaa gacaagacac ttatgtctga tatagataat ttttcaatca aaggtggtaa
    23401 aaaaccaaat gatgatgaga agatgtatca acatgactat gcaagtattg tacctttaat
    23461 ttcaaaaaag ataacagctg caaatgtatt tgatttcaat agaggcgatg aaactttaaa
    23521 atctgtaatg ttcttaactg aaagtatagg agctaagtat gaagtatatt atgctccagt
    23581 agtaaatggt atacctcaag aaaacaatat gaaaaaatta aaagaaggta ctgcccaata
    23641 ttcaggatac ataacagttc caattgattc ttttgatata ccagaaggaa agggtgcaat
    23701 tgtagtcagt atagagggga aaaatggaga gtcaactata ggttctgagt caaatgtacc
    23761 aggatatgat acatttaaag caaaagctaa tttaggtgaa agttatatca tagataatac
    23821 tggaaaattc tttgatataa atagagatag taacttctat ccgtgtaatt ttactataaa
    23881 agctgttaca gaaaagtctt ctggtgagag tatcccaaat gagtctttaa ttggtagtga
    23941 tagatatgaa actgctatca aagttagtca aaatggtttc aattcttcag aaaatgtagt
    24001 tttagtaaat ggcagttcaa tagtagatgc attggcagca actcctttta catctgctat
    24061 aaattcacca atattattga cacaaaaaga agctttaaat tcaaaaacta aagctgagat
    24121 acagagatta ggtgctaaga aagtatacct aataggtgga gaaaattcta taagtaaaga
    24181 aattgaacaa caattaaaaa gcttaaatat atcgatagag agaatatcag gaagtgatag
    24241 atacaagaca agtttattat tagctcaaaa gttaaatggt ataaaaaatg tatctcaaat
    24301 agcagttgta aatggagtga aaggattagc tgatgcaatt agtgtaggcg ctgcagcagc
    24361 agaaaataac ataccaatca tacttgcaaa tgaaaagagc gaattgcaag gagctgatga
    24421 atttctaaat tcattaaata tagagaaatc ttatattatt ggaggaacag catccctatc
    24481 aaacaatcta gaaagtaagt taaaaaatcc aactagatta tctggtagta gtagagacga
    24541 aactaattca aagataatag ataattttta taaaaaagat actttaaaaa atgcatttgt
    24601 agttaaaaat ggaatcaaga atcaaaatga tttaatagat ggattggcag ttggtccttt
    24661 aggagcaaaa actgggtcac cagtaatttt agttggtgat aaattagctg atagccaaaa
    24721 agaagttctt aaaaataaga ctttagaaaa agtaactcaa gttggtggag gagcaaataa
    24781 aaatgcattt aaagagttag taaaattaaa aagtgctaaa taaggtactt aagtattaac
    24841 atatactagt gtctattagt aatttatctt aataaaagct gaaaataatt actttaaatt
    24901 attgataaat aagataatca atgattgtaa aattttattt tcagctttaa atttatgtag
    24961 tataagttta aaaacataaa aaagggttac tttatataga aatatagaaa atcttacatt
    25021 ttatatataa ataacccata tttaattaac tttttatagt gttctaatag atattattga
    25081 acttaatggt aaatataatg tgtaagtttc atttaaagtt ggattagatt catctatata
    25141 tcttgagcaa agtgtaattg ataagctatc tgcttctata atttcaccat atagaggaca
    25201 actgctaaag taagaatgta cttcaacata tttatttaag ttttcttgaa cataatcgta
    25261 aaaacggttt tttgtagtag tagccataaa atcaactcct ttatttttta ttaaagttga
    25321 aacttttaaa aagataaata tgattacttc tattagaaac taagttaaaa aataagcaaa
    25381 tagatatgaa aattagaata atatattatt tatatcttaa ttataacact agataataaa
    25441 aaatgctata taaaattcag aattttcgaa agtttttaag cttattttta aatatactaa
    25501 taatactatt gacattagat agaaaaagta ttatattgac tatataaatt attttagtca
    25561 aactggagga aaaagatgcc taaatcatat tctgataaag aaagagagta tataataaaa
    25621 agacttaaag aagaagcaag attgtgtatg gagcaatatg gtattagaaa aactactgtt
    25681 gatgagcttg taaaacgggt aaaaatacca aaaggaactt tttatctatt ttttcaatca
    25741 aaagaattgc tcttttttga ggtattaaga gatatacatg actctataca aaaagaaatc
    25801 ttatatgaga taaatagagt agatgaaagt attacatgtg aacaattgac agatatattt
    25861 atgaaattct ataggatggt tgatagtact tcaattttaa atctcatgat aaatggagaa
    25921 tttgagatat tggtgagaaa gttaccagat tctataattg aagaacactt tagacatgat
    25981 gactttgaaa ttggagagat tatatcttgc ataccaaatg caaaaaataa agacatagaa
    26041 agctttagtg gagcatttag agcagttttt cttaccatgc tatataagcg cgaggttgga
    26101 agtaattgtt ttgaagatgc tttaagatta atgataaacg gattagttat acaacttatg
    26161 gaatagaatt taaattttgt ttgctaataa cttttattaa aaattattaa caaacaaaaa
    26221 aattatattt tattgatcat atagtcaaaa tagtcaaaaa tttgaaaggg tgatattgaa
    26281 tgattaaagt tgatgattta tcatttagtt atacagatag agatttttta caaaatatta
    26341 actttggagt aggaaaaggg gaaatactag gatttttagg accatcaggt gcaggaaaat
    26401 ctacattaca aaagattcta attggaatga taactaatta tggaggaagt gtcattgtaa
    26461 atggagtaga gagtaaaaga cactcaaata aattttatga aaatatagga gttgattttg
    26521 aatttcctag tttatatgaa aagttgactg caatagaaaa tttaaaatat tttgggtctc
    26581 tatattctaa aaaactacta tctattgatg agttattaaa atcagtagga ctagaaaatg
    26641 aagcaaataa aagggtatct gagtattcaa aaggtatgaa atctcgatta aattttataa
    26701 aagctttatt acataatcca gatattttat ttttagatga accaacaagt ggtcttgacc
    26761 catcaaatag caaggttatg aaagatataa ttttatcaga aaaattgaaa ggtaaaacta
    26821 ttattttaac aactcataac atgttagatg caacagagct ttgtgacaga gtagcgttca
    26881 ttgtaaatgg taaaatatct gctttagata caccacataa tcttattatg tcaaaaggag
    26941 ctattaaagt tagatatact tactttgata atggagaaaa aactgctgaa tgttttctga
    27001 acaatactgc taatgataaa aatttgaata tgcttattga gaaaaataaa cttttatcaa
    27061 tacatagtag tgaaccaaca ttaaatgata tttttattga gataacaggg aggaatttac
    27121 aatgaggcta aaaaatctta ttttaggaga tataaagttt caatttaagt atggttttta
    27181 ttttttatat ctttttttaa gtattatata tatttgtatt atcaatgtat ttccaacttt
    27241 tatgagagaa aaaatagtta taattatgat ttattctgac ccagcagcaa tgggattgtt
    27301 ttttatggga gctattgtac ttcttgagaa aagtcaaagg gttttaaatt ccttagctgt
    27361 atctccagta aaagtatctg agtatatttt atcaaaggta atttcattag gagtaatatc
    27421 tagtattgta gctatgttta ttgctattac attaaattta gataatatta taatatcaac
    27481 tataggtacc tttttttctt ctattatatt ttctttgctt ggattgatac ttgcaagtaa
    27541 agcatctagt ttgaatcagt ttattgtttt aagtattcct attgagatta tatgctttat
    27601 tccaccaata ctcaatgtac ttcttgacac aaaatcatat gcaaatttgt acc
//
LOCUS       DAEOTL010000048        25842 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEOTL010000048 DAEOTL010000000
VERSION     DAEOTL010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.048"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     misc_binding    253..515
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            591..3257
                     /locus_tag="KRH82_002435"
     CDS             591..3257
                     /locus_tag="KRH82_002435"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBG8655708.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            3682..4392
                     /gene="rgaR"
                     /locus_tag="KRH82_002436"
     CDS             3682..4392
                     /gene="rgaR"
                     /locus_tag="KRH82_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBG8655709.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
     gene            5438..6469
                     /locus_tag="KRH82_002437"
     CDS             5438..6469
                     /locus_tag="KRH82_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBG8655710.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            6602..7900
                     /locus_tag="KRH82_002438"
     CDS             6602..7900
                     /locus_tag="KRH82_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBG8655711.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(8014..8259)
                     /locus_tag="KRH82_002439"
     CDS             complement(8014..8259)
                     /locus_tag="KRH82_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBG8655712.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            8407..9273
                     /locus_tag="KRH82_002440"
     CDS             8407..9273
                     /locus_tag="KRH82_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBG8655713.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(9277..9813)
                     /locus_tag="KRH82_002441"
     CDS             complement(9277..9813)
                     /locus_tag="KRH82_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBG8655714.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(10004..10207)
                     /locus_tag="KRH82_002442"
     CDS             complement(10004..10207)
                     /locus_tag="KRH82_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBG8655715.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            10498..11262
                     /locus_tag="KRH82_002443"
     CDS             10498..11262
                     /locus_tag="KRH82_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8655716.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            11651..12964
                     /gene="prdC"
                     /locus_tag="KRH82_002444"
     CDS             11651..12964
                     /gene="prdC"
                     /locus_tag="KRH82_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBG8655717.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      13368..13453
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            14035..16182
                     /locus_tag="KRH82_002445"
     CDS             14035..16182
                     /locus_tag="KRH82_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBG8655718.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDSQTPDVEKPSDGQMPDVEKPLDEQTPEEEKPLEEK
                     IVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQVFTSKDSFISL
                     WYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVGASSKDDKYVIE
                     GEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSILYAGSEFDGFGY
                     KQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSINLCDKLIERAKTEEE
                     RAEYQKRKEVAINTKAYLEALLKAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYET
                     EAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVEISTQQKFKLKSVGKPDAKANIS
                     AVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPT
                     DDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPP
                     VPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNPPVPSVSDTVEKTPELSRDDTIIK
                     SPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            16589..18349
                     /locus_tag="KRH82_002446"
     CDS             16589..18349
                     /locus_tag="KRH82_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBG8655719.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIYEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            18778..20658
                     /gene="prdA"
                     /locus_tag="KRH82_002447"
     CDS             18778..20658
                     /gene="prdA"
                     /locus_tag="KRH82_002447"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBG8655720.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            20739..21023
                     /locus_tag="KRH82_002448"
     CDS             20739..21023
                     /locus_tag="KRH82_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655721.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            21061..21786
                     /gene="prdB"
                     /locus_tag="KRH82_002449"
     CDS             21061..21786
                     /gene="prdB"
                     /locus_tag="KRH82_002449"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:21511..21513,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBG8655722.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            21866..22624
                     /gene="prdD"
                     /locus_tag="KRH82_002450"
     CDS             21866..22624
                     /gene="prdD"
                     /locus_tag="KRH82_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBG8655723.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            22639..23106
                     /locus_tag="KRH82_002451"
     CDS             22639..23106
                     /locus_tag="KRH82_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBG8655724.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            23124..23606
                     /locus_tag="KRH82_002452"
     CDS             23124..23606
                     /locus_tag="KRH82_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBG8655725.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            23626..24633
                     /locus_tag="KRH82_002453"
     CDS             23626..24633
                     /locus_tag="KRH82_002453"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBG8655726.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            24753..25634
                     /locus_tag="KRH82_002454"
     CDS             24753..25634
                     /locus_tag="KRH82_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBG8655727.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT        10334 a         2904 c         4714 g         7890 t
ORIGIN      
        1 catataatat aaaaaatacg aataagaggt atactgtaag gataatataa tataaaatta
       61 atgagaaagc attaaaatta aaataaaata atcttgcaat tattgacatt ataagacaga
      121 ataactgtaa aaacatattt taaaatataa caactatata aaagagaata gacataatta
      181 agaaaattca gaaaaaataa aataaaaata attgacaaag agaataatat ttgtatataa
      241 taatatgtaa tattaaagac tgagaagaag aggagtaagt aaatactact aaaagagagg
      301 aaaattcact ggctgtaaga ttttctaagt ataagattta ctgaatgtag ctttggagtt
      361 tctaaactga actataagta agtttagacg gttagaaccg ttaaattctt tgagagtcaa
      421 agttgataaa ataacattaa ccaataattt aattatatgt taatgtattt taagctttgg
      481 aattaaggtg gtaacgcgag cttttcgtcc tttttaaaga ggatgaagag ctctttttta
      541 tttctaaaga tatttaaaaa atttatttat aaaatacagg aggcaggaca atggaaaata
      601 cgaatttatc aaaaacttat aacccaaaag attttgaggc taggctatat aaaaaatgga
      661 tggatgaagg gtattttaaa tctaaaccaa atccagataa aaaaccattt acaataatga
      721 tgccaccacc aaatataaca gggcaattgc atatgggaca cgctcttgac catacacttc
      781 aagatatatt aatcagatgg aaacgtatgg atggatatga agctttttgg cttccaggaa
      841 ctgaccatgc ttctatagca acagaagtta aagttgttga aagaataaaa aaacaagaag
      901 gcaagacaaa gtatgaaata ggtagagaag aatttttaaa gagagcctgg gaatggaaag
      961 atgaatttgg aggaaaaata tctaatcagc ttaaacaact aggtgattct tgtgattggg
     1021 ataaagaaag atttactatg gatgaagggt gtaatgaagc agttatagaa ttttttgtaa
     1081 gcctatatga aaaaggtcac atatacagag gaaatagaat aataaactgg tgcccagatt
     1141 gcaaaactac tttatcagat gcagaagttg aacatgaaga acacgacgga aacttttatc
     1201 atataaagta cccactaaaa gatagtgaag actttttaga aatagctaca actagacctg
     1261 agacaatgat aggagatact ggtatagcag taaatccaga agatgataga tataaacatt
     1321 taataggaaa aacagcaata cttccattag taggaagaga acttccaata gttgcagata
     1381 gttatgttga tttagagttt ggaactggtg cagttaagat gactccagca catgacccta
     1441 atgattttga agtaggatta agacataatc ttgagcagtt aaatactatg aatgaagatg
     1501 gaactatgaa tgaagtttgt ggaaaatatg aaggtatgga tagatttgag tgtagaaaag
     1561 ctatcgtagc agacttaaaa gaacaaggtt acctaattaa gataaaagag cataatcata
     1621 atgtaggaac ttgttataga tgccatacag tagttgagcc tagattatca gagcaatggt
     1681 ttgttaagat ggaagaactt gcaaaaccgg ctatagatat tcttaaaaaa ggagaattag
     1741 aatttgttcc agataaattt gataaaactt atttacaatg gctagaaaat ataagagatt
     1801 ggtgtatatc aagacaatta tggtggggtc atcaaatacc agcttattat tgtcaagagt
     1861 gtggagaaat agtagttgct agaaaaatgc cagataagtg tcctaaatgt ggaagcactc
     1921 attttaaaca agatgaagat gctttagata cttggttcag ttctgcatta tggcctttct
     1981 ctactctagg atggccaaat aagactgaag ctttagatta ttattatcca acaagtgtac
     2041 ttgttacagg atacgatata atattcttct gggtagttag aatggcattt gcaggtatgt
     2101 tctgtatgaa tgaaaagcca tttgaccatg ttttggttca tggattagta agagattctc
     2161 aaggtagaaa aatgagtaaa tctttaggaa atggtatcga cccattggag ataatcgagc
     2221 aatatggagc tgatgcccta agatttacat taacaactgg aaattcccca ggaaatgata
     2281 tgagattcta tatggaaaga gtagaatttg ctagaaactt tgcaaataag ttgtggaatg
     2341 catcaagatt tgtatttatg aatattgatg aagatataat taaaaacatg actagagaaa
     2401 gtgttaaaga ggacttaact ctagctgata aatggataat atcaagagca aataatattg
     2461 taaaagaagc aactaataac atggataagt ttgatttagg aatagcactt caaaagatat
     2521 acgattttac ttggtcagaa tactgtgact ggtatattga aatggttaaa cctagattat
     2581 atggagaaga tgcaaatgct aaatctgcag cattatatac attaacttat gttcttgaaa
     2641 aaatattaaa attattacat ccatacatgc catttataac agaggaaata tatactcatc
     2701 ttcctactgt tgaaggatgt ataatagtat ctgaatggcc aaaatataat gaagaagata
     2761 acatggctga agaagaagat atgatgaact tattgatgga aggtataaga agtataagaa
     2821 atgtgagagc agaaatgaat gtaccacctt ctaagaaagc taaattgata ataatcccaa
     2881 gtgaagaaaa aatagaagct attgagcttg gtaaagacta ttttataact ttagcatctg
     2941 cttcaaatgt agagatagca aaagataaat ctaatgttcc agaagatgca gttggagtag
     3001 ttattgatgg tgttgaaata tttatacctc ttaatgaatt agttgatttt gaaaaagaaa
     3061 ttgagagatt atctaaagaa aagaaaaagt tagaaggcga aataaagaga gttaatggaa
     3121 agcttgcaaa tcaaggtttc ttagcaaaag ctcctgaaag tttaattgaa gaagaaaaag
     3181 caaaaaaaga aaaatttgaa gagatgatta aatctgttga ggaaagatta acaaatttag
     3241 aatctaaaat aaaataaata taagaattag taaaaacata caaaaagtat atattctata
     3301 ctttttgtat gtttttcttt atatatatac aaatatgatg ttataattct ttacagatgt
     3361 gttatatttt tattttatgt tgtgaatata tgaattttat gtcttaaaat ttataagcaa
     3421 taaaaatttg atatattatg atgtttaata tagggtaata aatacatatt atatttattt
     3481 tactatattt ttttacataa tatatctaga aaagtatagg aatttatcgt aatttaagtt
     3541 taaatattaa agagaatttc tataagtagt ttaatcgaca atttaaattt ataaagaaat
     3601 ttaaatttga aagctagtga gtacagtttg gaaattgaaa taaagtaaac taaatgatat
     3661 tttagatttg gaggtgatat tatgttcagg gtagttatat gtgatgacga aaaaatacaa
     3721 agaagcatac taaaagagtt tacagaaaaa cttttgtctg aaagatgtct aaattatcaa
     3781 atactggaat tttcctgtgg agaagattta atatccaaat acccagaaaa aattgatatt
     3841 atatttttag atatccaaat gaaagatatc aatggaattg aggtggctaa aaaaataaga
     3901 aagtttgatg aaaaagtaga aattatattt acaacggctt tttcagagta tgccccccaa
     3961 ggttatgagg ttcgtgctta tagatattta gtaaagccta tagagtatag taactttgca
     4021 atgggtgtaa atctttgtat tgataacctt caaagaaaga aggagcgtta tatagtttta
     4081 aatagtaaaa aaggatttaa tagaatactg atagattcta ttttatatgt tgaaactgta
     4141 aagagagatt tagtcgtaca tacaataggt agagattata aagctaatat gagcatgaaa
     4201 caagcagaaa aattactgtg tgaaaatggc ttttttagat gtcatacaag ttttattgtt
     4261 aatttaagaa gaatagaaga tcttagggat aatatgatta ctattaatga acaatttata
     4321 cctataagta agtatagact taaagattta aaagtagcat taacaagctt gttatgtgat
     4381 ataatgtatt aattttaaaa aggtaattga aaatatcgta aaaaagattt aatgtcatca
     4441 cagggctatt gattgaaact gtcttaatat ataaaatgtt atttatatta agacagtttt
     4501 attatgcaaa atagtagttt atagattttt aatatggttt aacatgtata tgtagagttt
     4561 ccattataat agcatgatta ttaattagta gcttgattat caatatacta ttattgattt
     4621 ttatatgcat tatatgtatt tttagaatat gattaccttt ttaaaataat gactatttat
     4681 aaaactctat agatatttgt ttcatttagc tacgcatact ttaattaatt atattaatat
     4741 ttaatggagt acaatataaa tattaaagcg acatcttata gtttattgaa cctatagtaa
     4801 tgaattaata aatagtttaa ttctatgaaa agatttcctt ttatgcaatt tatttattga
     4861 aatatgatat aatatataaa ggtgtaagta ttagttgtta aaataatatt tatattagtt
     4921 tttatacata cttggtataa gtttttcata tattgattaa aattgatgtt gatttattat
     4981 ttttagtatt ttttcacctt ttgattcata ctttgtagaa tggtgtattt tctaaaactg
     5041 attataagac aagttcattc aaattagcat ttttatatca tataaataat tgttccccct
     5101 aaataagatt tagatgtata gtattaaaat caaaaagtat aaaataaaat tgatgcttaa
     5161 tcatagataa atattaataa aatatacaag gggattgtct aataaaaaga taatctcctt
     5221 ttttacaaat aattctaaat tgtgatataa atctaaaaat tttatcttaa catttaacca
     5281 tttaatgata ataattgata taataaatat aaattaaata tatggtgtac ttattttatg
     5341 tttttagcaa gaaatatagc atttaaaaga taaattgtgc aacttaaatc aaagtttaag
     5401 atgaactatt aacatagata tattaaaaac ttttgtaatg gagaatatat gtgatatgaa
     5461 taataaagtt aaggttgcag tattagatac aggaatagac aaagaacatg attacttaaa
     5521 agataattta gttggaggaa ttgcttttga atgtatgcat gattatatct ttatatcaga
     5581 taaatttgat gatgaagatg gtcatggaac tgcttgtgca tcaataataa agaaagagta
     5641 tgaagatgta gagttatttg taataaaaat tttgagaaaa gatggtatta caaatataaa
     5701 agttcttgaa gaagcattaa gatacctttt agacactaac ataagattaa ttaatttaag
     5761 tttatcagtc ataggagtag aaagtgttaa gggcttattt gaagtttgtt atgaattgtt
     5821 tagaaaagga aaaataatag tatgttcact cgctaatgat tttgacttaa gttatccagc
     5881 tatgtttaac aatgttatag gtgtaagagg atttacttta gatggagatg attcattttg
     5941 gtacaacaaa aaatatgatg ttcaatgtgt tatggatagc aattcatata taagttgtga
     6001 tataaataat tcctatagat taccaccaaa atgtaatagt tatttatcag caaagcttac
     6061 tggtaaaata gctaagatat tatcagaaaa accaggcata acaatatctg atttaaatga
     6121 taagcttgaa tcattagcaa ctagaaatca ttgggatagt tgtgattttg atgagtgtag
     6181 tagaattgta aactttaaat tggatttgta tgacaaagaa aatgctcttc ttatgaaagt
     6241 tgctgacgtt gttagggatt gcttagatat tgaagataat aatgaaaaac tctttaaggg
     6301 tagccttttt aataaggaga taggcttggt ttatgataat tgttttaatc tgttgaaaaa
     6361 gctagagcat agatttgaca taaagtttaa ttatatggac atctcaaaat atgacttagt
     6421 ttcaatatat acactgactg aattagtgga aagatataaa aacttataaa taaagatttg
     6481 tagctaaatt taatgtagaa ggtattaaat tatatgtatt ctttgtcggt agattaaaag
     6541 taaaaaatat actataatta gatagcataa gagaaaatgc caatacaggg ggagttagat
     6601 aatgaaatat gaagaagcat tagagtacat atcacaaact aataaattcg gtataagatt
     6661 aggattagaa aatatcggaa agttattaga attattagga aatccacaag aaactttgaa
     6721 tataatacat gtagctggaa ctaatggaaa aggttctgtg tgttcttttg tttctaatat
     6781 actaagagag tgtggatata aagttggttt atatacatct ccatatttag aaacttttac
     6841 tgagcgtata agagtaaatg gacaaaacat accacaggat gatgttgcta gaataattga
     6901 gttaataaaa gaaaaaatag agattatggt aaaagaaggc tatgcatatc caacagaatt
     6961 tgaagtggtt actgcaatgg cattttatta ctattcagaa caaaaggtag actttgtggc
     7021 attagaagtt ggtttaggtg gcagatatga tgctacaaat ataataacaa aatcacttgt
     7081 aagtgtgata gtatctataa gtttggacca tacaggtata cttggagata caatagaaaa
     7141 aatagcgtac gaaaaggctg gaataataaa ggaaaatgga gtagtactag tatatgacca
     7201 gactgatgaa gcaaaggatg ttataaagtc agtttgtaaa gagaaaaaag ctaaatatat
     7261 agaagttgat tttgatgata taaacataaa aaaatcagat ataaattctc aaatatacga
     7321 ttgtactgta atgaaagaaa cttatagaga ccttgaaata aaattgatag gcgaacatca
     7381 aataaacaat tctatcttgg caattagtgt aataaaatat ctaaaagaca taaataaatt
     7441 agcaaatata aatgaagaat ctataagaaa aggacttata aatactaaat ggccaggaag
     7501 aatagaaaag ataaaggaaa atccaatttt tataatagat ggtgcacata atgaagatgg
     7561 agcaaaatct ttggcaaaag cacttgataa gaattttaaa ggtagaaaat taaccttatt
     7621 aataggtatg ttagaagata aagatattga tagtgtttta gagatattgt tgtcacattt
     7681 taataaggta ataacaacaa caccaaataa cccaagggcc ataaattcag atatattaag
     7741 agaaaaagta ttaaaatatg tagatgatgt aacatcaaag catgagatag aggatgcagt
     7801 aaattataca ttagaaacat caagtgagga tgatattata ataagtgcag gttcattata
     7861 tatgattggt acagtgagaa ctttagtaaa gaaattataa ttttataaaa taagtataca
     7921 aataaaaata taaaaaagag ttgtctaaaa aatggacaac tctttttata taaaataagt
     7981 ttttaataat tttactgatg tttatataag taattatata gattgacgta tagctttaga
     8041 taattggtct gggcaagaag taccttttcc accacagtca ataccattta atttatcagc
     8101 aacttcaaga gcattttggc caattattaa gcttctaagt cctgataaat taccattaca
     8161 tcctcctata aactcagcat caacaatcac attattttca tcaacttcaa aaatcatttc
     8221 tctacaacat acaccacttg gattaaatgt tactttcatt aaaaagacct ccattaaata
     8281 ttatttcttt ttttaacatt aataataata ccaaatatat gcgtaataat gcaactataa
     8341 agcataatac aagctaatga aataatatat tattgtagta tatgtattgt agagaggagg
     8401 ggttatatga aaatctatat ttctaactac ttatcaaaga gtattagcat agttgattat
     8461 tctacacttg aactagaaaa agaaatagta ttagaagata atatatatcc acaccatttt
     8521 tgcatagaaa aagaaaaaaa tttaatatac atacctagtt caagtaatgg gatactctat
     8581 gtcttagatt taagtaatga taaaataatt gatactgtct ctataggagg aagtcttagt
     8641 caagttgtac ttagcgataa tgaattgttt gtggcaaatg aagattctaa tagtatatat
     8701 gtactagata aaaacacatt aaatccaata ggaattattg gagttgataa tatgccacat
     8761 ggatttgact ttgatagaga aagcaaaaag ttatatgtac cgtgtataaa ctcgatagta
     8821 tgtatagata caattaataa aaatatacaa aagaaaataa atatggactt tagagcttgg
     8881 catatagaac ttgataaaca aaagaaagaa atgtatatat caacacttga tggaaagctt
     8941 ataataatag atgaagtaag catggatata aaaaaggtat tatatgaatt tttattacca
     9001 gtagaaataa gatttaatta tagtggcaaa aaagtttatg ttgctgattt gggttataat
     9061 aatgtaagaa ttttagatta tacaacgagt agatacattg gaaatattga aataaatggg
     9121 attccccaag gattagaaat atctaaagat gaaaagttac tatttgtatc agatacacaa
     9181 gaaaattcag taaaagttta tgaaactgca aataacaaat taataaaaga aatcaaggta
     9241 ggaaaagagc ctacaactat aatttgtttg taggctttaa tgtatgtctc ttataagtaa
     9301 atcgataact tcggcataca tataagatgc attatttttc cagttattgc aaataagttt
     9361 tgcttgtttc tctgatgaaa catttagatt taaatctatt aagttagact gattttctat
     9421 gactctaagg ttgacaataa attcattatc actttgtttt acaaaactag actttacttg
     9481 agtatctgct agtagatttt ctttgttaga atctatatac ttgtctattt tttcagtaac
     9541 actagtaggt attcgattaa agaagtattc tagactttct acgcctcttt gagtaagagc
     9601 ataatattct ctgtcagagt ctttatatgt agtcaaaaac ttagattcca taagctgaga
     9661 taaaagctgt tgtaatgaaa aataattcat catctcagtc tctaatacta cttgagttat
     9721 ttgagaatta gttaaatcca ttttaatttt ttctaatata tataaaatta aaagtttgtg
     9781 ataggctaat tcttcagacg agttttcaaa cataaatatc atcctccgtc aaactatttc
     9841 tatatataat atattaaact aatttgtaca aaattaaaag aacaatttgt attgtattat
     9901 taatctttaa taattcatat aaaaacaatt ttataaataa atatagagaa acagggctgc
     9961 taattagcag ccctgttgat acccaggtgt caaaatttac tatttatttt ccagccattt
    10021 gtctttcagc catttcaact aatttcttag tcatatatcc accaacatat ccattttctc
    10081 tagctgttaa gttacctttg tctatgtttt catagttaga taaacctatt tcgttagcta
    10141 tttctaattt catttggttt aaagcagctt ttgcttctgg aactactgtt ctgtttgaat
    10201 ttgacatagt aaatttcctc ctcaaataat tagtttatga tgtctaacaa cacttttatt
    10261 tatgtgatgt taatactaat ttctccaaaa taaaaataat atatacagaa aaataaaggt
    10321 aaaaatgtaa aaaatataaa aaaattaaat aaatgagtat tttagagagt ttaattaggt
    10381 caatataggt tttatttttt tagttattgt cttataaatt aaatattaca gtactttttt
    10441 gagctgaaaa aaaataaatt ttaaatatag aagaaattat ttcaaagggg gaatagtatg
    10501 aaaagagaag ttaaaaggac taaagctttg atatatagtg ttttattttt ttcattatta
    10561 ttagtgttaa tatttgtttt tgtttatgga ataaaataca tatgttctaa atctgacaat
    10621 tcaaaaatgc ctatatataa agttgataca aatgagaaaa aaatagcttt gagttttgat
    10681 gtagcatggg gaactgataa tatggatgat attttaaaaa ttttagataa acataatgta
    10741 aaagctacct tctttttagt tggtagttgg gtggatgata atgaagaaat tgtaaaagct
    10801 atagatgaaa aaggacatga aattggaaat cattcaaata ctcatgccaa tttgaaggaa
    10861 atatcaaaag aagacataac aaaagagata gaaactacat cagaaaaaat atataatata
    10921 acaggaaaaa ggactaattt atttagacct ccttttgggg acgtaaacaa taaagctatg
    10981 gacatttgta gtgatttagg ttataaagta attaagtggg atgtagattc tatagattgg
    11041 aaggagcttg gaccaaatca tgtaattgag aaagtaataa aagaatctca acctggttca
    11101 atagttttat tccatgctaa tataaatgat gtagataact atttggatac tataataagt
    11161 cgactaaaaa aagatggata cagtctagtc aaaatatctg atttgttgta taaagataat
    11221 tatgtagttg attccaatgg agtgcaaaaa actaagaatt aataagtaat aaatgtatat
    11281 tttaagtaaa gttgtgataa attatatagt atatgttaga aaagtgtcga taaaaagacg
    11341 gtgtctattt tttgacactt tttatacatg tatgcaatat caataattat agattaaatt
    11401 gattaaaaaa gtgtctaata attgactttt ttttgatggg tttaaaaatt tagaagaatt
    11461 aatgaatgct gtaagacagt atttccaaag ggtataagtt tgtttaaaag ttggcataga
    11521 aattgctttg ttaataagcg atatgttcta tagaaataaa caatatgtta agaccttata
    11581 atagaaaaat agcattaaca ttatttgaac agcttataaa aaaattaata tacttaaggg
    11641 ggcgtactag ttgaacaaac tatattctat tttattaaaa caacacgttg gtggtccaga
    11701 taagccagta gtaagtgttg gagatgtagt aaaaaaagga actctaatcg cagaaccaac
    11761 tggattaggg gcaaatattt atgccagtgt tagtggaaaa ataagtgaaa taaatgacca
    11821 agcgatagta attgaagctg atgaagtaca agaagatact tttgaaccat taaaaggaga
    11881 aggtatactt gacttaatta aagaagctgg agtagtagga atgggtggag caggattccc
    11941 tactcatgta aaattaaaca tagatttaaa tggtggaaca atattagcaa atgcagctga
    12001 atgtgaacct ttattagctc ataatataaa agaaatagaa gaaagaccag aaatagttta
    12061 tcaaggtata aaatatgcta tggaagttac taatgctgga aaaggtatgc tagcaataaa
    12121 aagtaagcat ccaaaagcaa tagaagcttt caaaaaagta ataaagccag gagacaacat
    12181 agaagttgca gaattagttg atatgtaccc aatgggagaa gagagagcaa tagtaagaga
    12241 cgttctagga aaattacttg agccaactca attaccttca gaggctaatg cagtagtaat
    12301 aaacgtagaa acactaacta gaatagtaga ggctgttgag caaaaaagac cagttatatc
    12361 taaaaatata actgtagttg gtcaattaaa cagtggaaaa gaatctatag tgtttgaaga
    12421 tgtgccaatt ggaacaactg tcggagaatt aattgaaaga gctggtggaa taaaaggtga
    12481 atatggtgaa ataatcctag gaggaccttt cactggtaaa gctactactt tagatgctcc
    12541 aataactaaa actagtggtg gtataatagt tactatgcca tttgttaatg aaaagagaaa
    12601 aatgggtctt ttagtttgtg catgtggacc taatgaagaa agaatgagag atatagcaac
    12661 taaaatggga gttactgata tagtatcagt tcaaaaatgt aaacaagctc aagaaattaa
    12721 aggtgcatta aaatgtgaaa atccaggaca ctgtccagga caagctcaaa aatgtattga
    12781 atttaagaaa gctggagcag aagttatatt aataggaaac tgtactgact gtagtaacac
    12841 agtaatgggt tctgcaccaa aattaaaatt aggtgtatat catattactg accatgtaat
    12901 gagaacagtt aatcacccat taataagaag aataaaaggt gacgtaagat taaaaataaa
    12961 ataatagata aatagaagtt agacatcttt agaagtaaaa cttaaaagtt acttctaagg
    13021 atgtttttta atgtattttg agggcaatat atatattgta aaataaatgg aaaaaataga
    13081 caaaatatgc tagatattgt ataatgataa caatagctat tacaattaat attggacaaa
    13141 aataatgata ctcaagtatg tggtttgtat taatatgcat attatattaa gtcaactatc
    13201 cgatagagta aaaggttttt gtgatatttg aagatactct atagtatctt ttttattata
    13261 aaaactaatt tttgtttttt attagataag tatctaggat actaatttat attttattga
    13321 gttgttaaaa aagtgcactt aaaaagttaa aaaagaaaaa ttaaaaacct atttatagaa
    13381 actgtgaagt atatcttaaa cctgggcact taaaagatat atggagttag tagtgcaacc
    13441 tgctataaat ataaatagga gtaactttta attgtcaaaa atatataaaa taaatacata
    13501 aataagtaat tgatagaaga tagatataaa tatatttttg aaatgctccc tgcattcata
    13561 acgagtgtag agtggcagat atctgcccaa aactccttta attgctggaa gttcctaaag
    13621 ctaactaaac cacaacataa tcatgaaata aggataagtg tgatagagtg tgcatttaat
    13681 aagcacttga ggttacgaaa gtagaaaaaa ttagttagat agcataaggt taaatcctaa
    13741 gtgccttgaa aatggataat cagcaggtaa gcttcgaaaa gaagaaactt caacgactag
    13801 agagaaatct cgtacctaca agtgtgggga aatggggagt acctaattta tggttaggta
    13861 atgagatagt ctgtgcttaa tagaaatatt aagaagttca taggagaact ggttaggagt
    13921 aacgacccta attgaacaca ctaaagatgt attattgaat aagattcata taatatttaa
    13981 taattttaat tatattaagt gaatacaata tatgttttta gtatcaggag aattttgaaa
    14041 acaaaaatta aaaaatcaag tataatcagt ttagtaattg cttttagtat ggtatttact
    14101 gcatttacac caatagtatc ttatgctgac gaagtgacta gcaatgatac aatacttaat
    14161 ggagaagaac aatcaaatgg tcagacacca gatgtagaga aaccatcaga cggtcaggta
    14221 ccagatgggg agaaaccatc agacagtcaa gtaccagatg gggagaaacc atcagacggt
    14281 caggtaccag atggggagaa accatcagat ggtcagatac cagatggaga gaaaccatca
    14341 gatggtcaga taccagatgg agagaaacca tcagatggtc agataccaga tggagagaag
    14401 ccatcagata gtcagacgcc agatgtggag aaaccatcag atggtcagat gccagatgtg
    14461 gagaaaccat tagatgagca aactccagaa gaagaaaaac cattggaaga aaaaatagtt
    14521 atagaggaaa tgagtttaaa acaagatatt gataaaattc ttgatatgac tttatctcaa
    14581 ataaataaaa tagtatataa cttttgggaa gatgaagaag atgtaaaggc agatgaacaa
    14641 tcagaaatta accaagtttt tacttcaaaa gactcattta ttagcttatg gtatgacaaa
    14701 aaagcaaaag taaaaaattc ttgtttacta aaagaaatag atggttcaga tagaccttat
    14761 catgatttaa gatttgatga tattacaaag actttaactt ttgactatgt aataaagggt
    14821 cttgtaggag caagctcaaa agacgacaaa tatgtaatag aaggtgaaga tggagagcaa
    14881 actgcatttt gttacaataa tcatttaaga ccaccaagta gtaatggaaa gagtccatat
    14941 ttaccagcag aagattttaa tggtcaagaa aaccaaaatg aagaagcagt taaatctata
    15001 ctatatgcag gttctgaatt tgatggattt ggatataagc aacaatttaa tttaggtgga
    15061 gaagaaaatg aattgatgac ttactcagct actcaaagtg caatttggat tattcttgga
    15121 caaatggatg aacaagaaag acttaagcag tatcaaggtt ctataaacct ttgtgataaa
    15181 cttatagaaa gagcaaaaac tgaagaggaa agagcggagt atcagaagag gaaagaagta
    15241 gcgataaata caaaagctta tttagaagca ttgttaaaag caggtcgtga agagttaaag
    15301 ccaaatgata caggaaaacc tagtttgagt aatggtttaa ctaagattaa ctttgaaaaa
    15361 aatgaagatg gtacttatga aacagaagct gtagccttag taggttatag tggtgtagta
    15421 aagttaaaac taccagatgg agtaactgct tatgatgtag atggtaatat aataggtaca
    15481 ggcgaagtag aaatttcaac gcaacagaaa tttaaactta agagtgttgg aaaaccagat
    15541 gccaaagcta atatttctgc tgtatcttat gattatattt ttccaaaagc tattcaatat
    15601 tataaggcag tgcttgattt aggacaaaaa gaccattcat cttcattacc atctagcaag
    15661 caaaatttat taagttatac aatagagaaa aagaatggtc aagaagttaa ctttaatata
    15721 ggtttaccaa cagatgatga tgttgtaaat ccaccagtgc caccaataga tgatgatgtt
    15781 gtaaatccac cggtgccacc aacagatgat acaaatggac ataagccaaa accatcacca
    15841 ccaatagatg atacagtaat aaatccacca gtaccaccaa tggatgatac aataataaat
    15901 ccaccagtac caccaacgga ggatgcagtg ttaaatccac cagtgccacc aatggaggat
    15961 gcagtgctaa atccaccagt gccaccaaca gatgatacag tgttaaatcc accagtacca
    16021 tcagtaagtg atacagtgga aaaaactcca gaactatcaa gagatgatac aataataaaa
    16081 tcaccaaaaa caggtgatga aactcagcta atgtcatatg tatttattag tgtcattgca
    16141 atttgtggat tagcgtatca atgtaaaata aaaagaaatt aatctagatt attattaagt
    16201 ttaaaataaa aagtctcaaa ttgatttata agtcattttg gggctttttt atgtaaatat
    16261 aatatgcaaa tatagtttgt ttaaaaatat ctatcttaat tatattctta aatttatgat
    16321 tggatacagg cattcattaa ttgtttgatg aatagaaaaa tgttttgaag gtgaaaatag
    16381 tattgaaaaa ataatatact aagggtataa ttcatttgat ttcatttgta taaatttaat
    16441 tataaatttt aaagtgatta tataaattta aatgctaatt acttaataaa ttttaataat
    16501 aattatttaa taaataatta ttataatatg ctagaataaa tatatataaa taagttttga
    16561 tgaggtacta ctataaaggg gggactttat gttttcgata ccagaagtaa aaaaagtaga
    16621 agaggtaatg gatacaaaat ttacaactat atacgaagac acaagaattg aagatgcaat
    16681 aaaagaaatg ataaaaagca acacaaaaac tctaatggta atagattcat ctgaccaatt
    16741 aaaaggcatt atatccatga cggatataca taatctttat gagatgcata aaaagtatga
    16801 aggtcaacca gtaaaactta taatgaagaa ggatgtaata tatgtcaacg aaggtttaac
    16861 cttagatgaa tgtagagata taatgatatt aaaaaatata gggattcttc ctgttcttag
    16921 agataataaa attattggag ttctaaaaca agagcacatt agggactatc tatatatgca
    16981 tttagaagat tatggattaa ctttgaagta tattataggt caaattaaag aaggaatttg
    17041 tgctataaat aacgaaggtg ttgttatctt gtggaataag tttatggagg aaaggtatga
    17101 tataaagtct gaagatatag ttggtcgacc gatgaatgaa tttttggaaa atactatttc
    17161 agaaaaagta ctaaatagta aagttggaat gagtgacttg tattttacag ataaaaaaga
    17221 aaatatgtat gcattagttc atgcaaatcc tatattttat aaagaagaat ttatcggtgt
    17281 tgtatgtaca gaagttgatg ttacagaagc taagatatta gctcttgaac ttgaaaaagt
    17341 aaatgataca ttaaaatatc taaagaacga agtcaaaaat ttatctaaag gtagttttga
    17401 taagatttta ggtaaaagtt ataaattgga aaaatcgaaa gcgattgcaa aacaagtggc
    17461 tagaacaaat agtagcatat ttatttgggg cgaaagtggt acaggtaaag aagtatttgc
    17521 aagagctatt catgattata gtgagagaaa aggtcaattt atacctgtta actgtagtgc
    17581 cataccaaat gagttatttg aaagtgagtt ttttgggtat gaatcaggtg cgtttacagg
    17641 agcaagtaaa aagggtcgaa taggtatatt tgaacttgca aaagatggaa ctgtattttt
    17701 agatgaaatt gccgatttac ctcttagtat gcaagcaaag ttgcttagag tattacagga
    17761 aaaagaaata agaagagttg gtggagatac cacaataaaa ataaatccta gaataatatc
    17821 agctaccaat aaagatttga gtaaaatggt aaaggcagaa aaatttagag aagatttata
    17881 ctatagatta aatgttgttg aaataaagat tcctccactt agagagagaa aagaagacat
    17941 aggattattg gttcatagct ttttagagga gatatgtaaa caaaataata agcctgttct
    18001 tacaattagc aaagatgtaa tagatatatt tcagaattat agatggaaag gtaatattag
    18061 agaattaaaa aatacgattg aaaatattgt tgtattgtca caaaattcta aaatagatgt
    18121 ggatgatgta ccaagttata tgatggattc tacaaataat agtactgaag aagaagagta
    18181 tcctttagat ttaacgaagg caactcaaaa aattgaaata aagaatataa ccaaggcact
    18241 taaaatgtct aatggaaata aagctaaagc agctaagata ttaaatatac ccagaacaac
    18301 tttgtattat aagatagacc aatacaaaat agatgtgtct aaaatatgac acatgactaa
    18361 attttgacaa aatgataaac tttaatttaa aacctagtaa agccaacgct tgtataagtg
    18421 ttgtgtatat agatgtgtta aaaaaaatga aaaagtgttg attaattgac actttttttg
    18481 tttgagaaaa tgtttacaaa tacaaaaaat aacatatttt aaataaatat ttatataata
    18541 tttggctaaa aatagcgata gatgaagaat ctattataga aaaaatcttt ttgttaataa
    18601 gttggcatag gaattgctta taatataaag tgactttaag tgagaaaaaa ataatattaa
    18661 tcataacaaa ttatgtaggt tttaatttac ttaatttctc agttaagggg ttacctgttg
    18721 aggaattgag atttaaaata ataaataaga aaataatgta aggaggtatt ttatactatg
    18781 tcaataactt tagaaacagc tcaagcccat gcaaatgacc cagcagtttg ttgttgtaga
    18841 tttgaagcgg gaacaattat agcgccagaa aacttagaag atccagcaat atttgcagac
    18901 ttagaggatt ctggattatt aacaatacca gaaaatggat taactatagg tcaagtacta
    18961 ggagctaagt taaaagaaac tttagatgca ctttctccaa tgactacaga taacgtagaa
    19021 ggatacaaag caggagaggc taaagaagaa gtagtagaag aaacagtaga agaagcagct
    19081 ccagtatcag aagcagcagt agttccagta agcacaggag ttgcaggtga aacagttaaa
    19141 atacacatag gtgaaggtaa gaacataagc ttagagatac ctttatcagt agctggtcaa
    19201 gcaggagttg ctgctccagt agcaaacgtt gctgctccag tggcaagtgc agcagcagaa
    19261 gtagctccaa aagttgaaga aaagaaactt ttaagaagct taactaaaaa acactttaaa
    19321 atagataaag ttgaatttgc tgatgaaact aaaatagaag gaactacttt atacatcaga
    19381 aacgcagaag aaatatgtaa agaagctaat gaaactcaag agttagttgt agatatgaag
    19441 ttagaaataa taactcctga taaatatgaa acttacagtg aagctgtatt agatatacaa
    19501 ccaatcgcta ctaaagaaga aggcgaatta ggttcaggta taactagagt tatagatgga
    19561 gctgtaatgg tattaactgg tacagatgaa gatggagttc aaataggtga atttggttct
    19621 tcagaaggtg agttaaatac tactataatg tggggtagac caggtgctgc tgacaaaggt
    19681 gaaatattca tcaaaggtca agtaacaata aaagcaggaa ctaacatgga aagaccagga
    19741 cctttagctg ctcaccgtgc atttgactat gtaactcaag aaataagaga agcattaaag
    19801 aaagttgaca actctttagt agttgatgaa gaagtaatag agcaatacag aagagaaggt
    19861 aaaaagaaag ttgttgttat aaaagaaata atgggacaag gtgcaatgca tgataaccta
    19921 atattaccag ttgagccagt tggtacatta ggagctcaac caaacgttga cttaggaaac
    19981 atgccagttg tattatctcc acttgaagta ttagatggtg gtatccatgc attaacttgt
    20041 ataggacctg catcaaaaga aatgtcaaga cattactgga gagagccatt agtaataaga
    20101 gctatggaag acgaagaaat agatttagta ggtgttgtat ttgttggttc tccacaagta
    20161 aatgctgaga aattctatgt atctaagaga ttaggtatgt tagttgaagc tatggaagtt
    20221 gatggagctg tagtaactac tgaaggtttc ggaaacaacc atatagattt cgcatctcac
    20281 atagagcaaa taggtatgag aggtatacca gtagttggtg taagtttctc agctgttcaa
    20341 ggtgctctag ttgttggtaa taaatacatg actcacatgg tagacaacaa taagtctaag
    20401 caaggtatag agaatgaaat attatctaac aacactttag ctccagaaga tgctgttaga
    20461 ataatggcta tgcttaaaaa tgctatagaa ggtgtagaag ttaaagctcc tgaaagaaaa
    20521 tggaatccaa atgttaaatt aaataacata gaagctatag aaaaagttac aggagaaaaa
    20581 atagtattag aagagaatga gcaatctcta ccaatgagta agaagagaag agaaatatac
    20641 gaaaaagacg aaaactaaaa tttagatact aactaagatt tagacaataa cataaattta
    20701 gatccaagtt taaaacagta tagagaggta gaattataat ggataggtta aaatatatct
    20761 catcagagac tttttatgaa ggtattatag ttgacatcaa aggtggtgga gtgactatag
    20821 acctaaaagg tagacttgga caatttaaaa tacctaatag aatgcttata actgactacg
    20881 aacttaagat aggtcaagaa gttggattca tgctaagcta tcctgaggta ttaagtccag
    20941 agcctaatca agagtatgta gaaaatatta ggagagaaaa agaaaaacaa gcagaaatgc
    21001 aatcaaaaca agaagaaaaa taataaataa tcgtttgaaa atagaaggga gaggaaatat
    21061 atgagcctta caacagtaca aggacttcaa tctgaaatat tcgttccaat aacacctcct
    21121 ccagtttgga ctcctgtaac taaagaatta aaagatatga ctatagcttt agctacagca
    21181 gctggtgttc atttaaaatc tgacaagaga tttaatctag caggagatac tacatttaga
    21241 gctataccta atacagctac agttgatgaa atgatggtat cacatggtgg atatgacaat
    21301 ggagatgtaa acaaagatat aaactgtatg ttccctatag atagattaca tgaattagct
    21361 gcagaaggat ttatcaaagg agtagctcct atgcactatg cattcatggg tggtggagga
    21421 aaccaacatg tcttcactga agaaactggt cctgctatcg ctgctaaact taaggaagag
    21481 ggagtagacg gtgtagttat gacagctggc tgaggtactt gccatagaac tgccgtgatc
    21541 gtgcagagag caatagagga agctggaata cctacaataa taatagcagc tcttcctcca
    21601 gtagttagac aaaacggaac tcctagagca gttgctccat tagttccaat gggtgctaat
    21661 gctggtgaac cacataatat agaaatgcaa acacatatat taagagatac attagagcaa
    21721 ttagttgcaa taccatctgc tggtaagata gttccattac catacgaata taaagctcac
    21781 gtttaaaatg taatttatat ttgaaaatat agaacccttc tcctacacgg ttaggagagg
    21841 ggttttaaga acaaaggtgg atattatgga agaaaaaata atgagaagac ttgttataaa
    21901 accgtttcat atgaatgaag ttaatttcgg ttcaaaaact tctataaaga aagatgtact
    21961 tacaatagat ttatcaagta tagatgaaat aaaagaaaga gaagagttaa taacagacat
    22021 aaaagtagac attataaaac ctggagatta tgacagagaa attaatacta ttatggacat
    22081 tataccaata tcaacaaaag ttttaggcag actgggagag ggtattacac atactttaac
    22141 gggtgtatat gtaatgttaa ctggtgcaga tgaagatgga aatcaaatgc atgaatttgg
    22201 ttcttcagaa ggaattttga aagaccaaat ggtatttggg agatatggaa ctccatcagt
    22261 tgaagattat ataatccatg tagatgtaac tttaaaggga ggtttacctt ttgaaagaac
    22321 acttccactt gcagcattca gagcatgtga tgattttata caagaaataa gagcgtcttt
    22381 gaaaatggaa gacggaagaa atgctactca agttcgtgaa tattttgaca aaattcgacc
    22441 aaatgcaaaa aaggttgtca tagtaaaaca aatagcaggt caaggtgcta tgtatgacaa
    22501 tcagttattc tcaaaggaac ctagtggatt tgaaggagga acatcaatta tagatatggg
    22561 aaatgtacct atgattatat ctcctaatga atacagagat ggtgccctta gagctatgac
    22621 ttaagagagg tggatattat gggaatagga ccttcaacaa aagaaacatc tcttcatcac
    22681 tttagagacc cacttttaga catagttgaa agtgataagg atgtagattt acttggagta
    22741 atagtagtag gaactccaga tggaaatgaa aataaaacct ttgtgggaca aagaacggcc
    22801 gcttggctgg aagccatgag agtagatgga gctatagttt catcagatgg ttggggaaac
    22861 tcacatgttg actacgctaa cacatttgag gaaataggaa aaagagatat acctgtagtt
    22921 ggagttacat ttaatgggac tcaagctaag tttgttgtaa gcaatcaata tatggatacc
    22981 atagttgata tgaacaaatc aaaagaaggt attgagacag aagtagttgg agaaaacaac
    23041 acaaatgaaa tagatgctaa aaaagctttg gcatttttaa aacttaaaat gagaaaacat
    23101 ggataaaaaa tttaagtaag ggaatgagtt ttgtgggaat ttctacatca atgaaaaaca
    23161 catcacttca tatatttaga gacccgttac tagatttgat agataatgat tctgacatag
    23221 acttgttagg agtggttgta gttgggacat cagagcacaa tgaatggaaa acatttttag
    23281 caactagact tggaagatgg attgaatcat tgcgacctga tggagtgatt ataactttag
    23341 atatggcagg aaaccaacat attgatttta caaatgctat agcagagttt gtaaaatcag
    23401 atatacctac agtaggtctt actattatgg gagcagatgg attagtaatt accaatccat
    23461 atttggataa agctaccata attgattata aaaagacaac aggctacata gaaacagaag
    23521 tagttggaga caatcacatg gatgaagttg atgttaaaaa agcattggct ttcctaaaat
    23581 taaaaatgcg taaagacgca aaataaacct aagggggaat ttgatatgaa atttagcaga
    23641 agtatacaag ctatagactc tcatacagca ggtgaagcaa ctagaatagt tgtaggtgga
    23701 atacctaaca taaaaggaaa ttctatgcct gagaaaaaag aatatttaga ggaaaatcta
    23761 gattatttaa gaactgctat aatgttagag ccaagaggac ataatgatat gtttggttct
    23821 gtaatgactc aaccttgttg cccagatgct gactttggaa taatcttcat ggatggtggc
    23881 ggatacctta acatgtgtgg ccatggtaca ataggagcta tgacagcagc tatagaaaca
    23941 ggtgtagttc cagcagtaga gcctgtaact catgtagtta tggaagctcc agcaggaata
    24001 ataagaggag acgttacagt tgtagatgga aaagctaaag aagtatcatt cttaaacgta
    24061 ccagctttct tatataaaga aggtgttgaa gttgacttac caggtgttgg aactgttaaa
    24121 tttgacatat catttggtgg aagcttcttt gctataatac atgcaagtca attaggttta
    24181 aaaatcgaac ctcaaaatgc tggtaaatta actgaactag ctatgaaact tagagatata
    24241 ataaatgaga aaatagaaat acaacatcca actttagctc atataaaaac tgtagactta
    24301 gttgaaatat atgatgagcc aactcatcca gaagctactt acaaaaatgt agttatattt
    24361 ggtcaaggtc aagttgacag atctccatgt ggaactggaa caagtgctaa attagctact
    24421 ttacatgcta aaggtgaatt aaaagtagga gaaaaattcg tatatgaaag tatattagga
    24481 actttattca aaggtgaaat agttgaagaa actaaagttg cagatttcaa tgctgtagta
    24541 cctaaaataa ctggttctgc ttatataact ggatttaatc attttgtaat agatgaagaa
    24601 gacccactta aacatggatt tattcttaaa taagtaataa ataaattagg aaattaaaat
    24661 agaatagtag ccacttgtcg gttgctattc tatagctttt aggctataag attcagaata
    24721 tatgaaaaaa taaaaaaata ggaggatgga ttatggtagc aatcttaaag gcattatatg
    24781 tagtattcgc agcaatcttt gcagttgtgt ttggtaaaga cgtagctaaa gcaaacaaag
    24841 aggggaaact agaagaacaa agtactccaa aagttgctgt aacaggattt ataacagact
    24901 tctttgatac attaggaata gggtcatttg ctccaacaat agcaatgtca aaggctttaa
    24961 agttaaatat accagataaa aaaatgcctg gtacattaaa cgtagcacat actattccag
    25021 ttgttacaga agcattcata tttacatcaa tcataccagt tgatggtgtt actttagtat
    25081 ctatggttgt agcagcagca gttggttcat atataggtgc aggaataata gctaagatgg
    25141 acgagagaaa aatacaactt gttatgggtg taactttagc attaacagca atattaatgt
    25201 tattaggtca tccttggatt aacgtattac caggtggagg aaatgaatta ggtcttactg
    25261 gtgttaaatt agtaataggt gtaataggta actttatact aggagcttta atgacagctg
    25321 gtataggttt atatgctcca ggtatggcaa tggtttattt cttaggaatg tctgcaaaag
    25381 ttgcattccc aatagttatg ggttcttgtg cattattaat gccagttgca agtatgaaat
    25441 tcataaaaga agatgcatat actaaaaaag catcagttat aatagctata tgtggtttaa
    25501 taggagtttt cgtagctgca tatatagtaa aaactctacc aatggatata ttaaaagcat
    25561 tagtaatagt agttatagct tatacttctg ctacaatgat aatggctgca aataaaaaca
    25621 aaaagactgc ttagttaaag actacttagt gtttattaaa tattacagct aataataaag
    25681 attataaact gctttaaaat attgaattaa tattttaggg cagtttttta tttactaaat
    25741 taatataaag caattaacat gccaattatg taatatatat agtgatttag tagatttaat
    25801 gtaaaaaacg ttgtattttt aaagaataaa gcataattta aa
//
LOCUS       DAEOTL010000049        25638 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEOTL010000049 DAEOTL010000000
VERSION     DAEOTL010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25638
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.049"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..975)
                     /locus_tag="KRH82_002455"
     CDS             complement(<1..975)
                     /locus_tag="KRH82_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBG8655728.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDN"
     gene            complement(1023..1883)
                     /locus_tag="KRH82_002456"
     CDS             complement(1023..1883)
                     /locus_tag="KRH82_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBG8655729.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2152..2361
                     /locus_tag="KRH82_002457"
     CDS             2152..2361
                     /locus_tag="KRH82_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBG8655730.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            2361..2627
                     /locus_tag="KRH82_002458"
     CDS             2361..2627
                     /locus_tag="KRH82_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBG8655731.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            2656..3228
                     /locus_tag="KRH82_002459"
     CDS             2656..3228
                     /locus_tag="KRH82_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBG8655732.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(3462..4652)
                     /locus_tag="KRH82_002460"
     CDS             complement(3462..4652)
                     /locus_tag="KRH82_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBG8655733.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSAGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(4912..5343)
                     /gene="dut"
                     /locus_tag="KRH82_002461"
     CDS             complement(4912..5343)
                     /gene="dut"
                     /locus_tag="KRH82_002461"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBG8655734.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            5456..7684
                     /locus_tag="KRH82_002462"
     CDS             5456..7684
                     /locus_tag="KRH82_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBG8655735.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHRECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(7795..8280)
                     /locus_tag="KRH82_002463"
     CDS             complement(7795..8280)
                     /locus_tag="KRH82_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8655736.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            8532..9755
                     /locus_tag="KRH82_002464"
     CDS             8532..9755
                     /locus_tag="KRH82_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBG8655737.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            9759..12893
                     /locus_tag="KRH82_002465"
     CDS             9759..12893
                     /locus_tag="KRH82_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBG8655738.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGEKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            12927..14225
                     /locus_tag="KRH82_002466"
     CDS             12927..14225
                     /locus_tag="KRH82_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBG8655739.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLMDKYEKDYDRYKKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLITLT
                     DYKKQVVSNEDAKNSYDSLIVNYNSLKNGIEKPWILNSGK"
     gene            complement(14501..14746)
                     /locus_tag="KRH82_002467"
     CDS             complement(14501..14746)
                     /locus_tag="KRH82_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBG8655740.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(14960..17587)
                     /locus_tag="KRH82_002468"
     CDS             complement(14960..17587)
                     /locus_tag="KRH82_002468"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBG8655741.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(17648..18490)
                     /locus_tag="KRH82_002469"
     CDS             complement(17648..18490)
                     /locus_tag="KRH82_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBG8655742.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(18497..19135)
                     /locus_tag="KRH82_002470"
     CDS             complement(18497..19135)
                     /locus_tag="KRH82_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655743.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(19571..20863)
                     /locus_tag="KRH82_002471"
     CDS             complement(19571..20863)
                     /locus_tag="KRH82_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBG8655744.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(20900..21256)
                     /locus_tag="KRH82_002472"
     CDS             complement(20900..21256)
                     /locus_tag="KRH82_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBG8655745.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(21291..21650)
                     /locus_tag="KRH82_002473"
     CDS             complement(21291..21650)
                     /locus_tag="KRH82_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655746.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAVISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(21719..23692)
                     /locus_tag="KRH82_002474"
     CDS             complement(21719..23692)
                     /locus_tag="KRH82_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBG8655747.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEICVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(23914..24927)
                     /locus_tag="KRH82_002475"
     CDS             complement(23914..24927)
                     /locus_tag="KRH82_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBG8655748.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(24940..25485)
                     /locus_tag="KRH82_002476"
     CDS             complement(24940..25485)
                     /locus_tag="KRH82_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBG8655749.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
BASE COUNT         8771 a         4263 c         3263 g         9341 t
ORIGIN      
        1 attatctaag tcttcatcaa acatttttat tatatttttt atctcatact tgtactcatc
       61 ttcattcatt ctataaagca ttaaatcttc tagtacatct ttcatatcga agtacacatc
      121 ttctaataaa taaaaatagc cttcctctat atctttcaat ttatctatag tatccatttt
      181 tttacttata tctttcataa tttctaaatt ttgtatattt acatctatga ttgttaataa
      241 gtacattctc acagttttta ttatttcaac agaaaaatct acaatattat aatttccttc
      301 ttttttatat aatgactcct taaatttgtt aaaacaatta tctaaattag aatttatatc
      361 gttaaatggt ggtcttatta tgtcacgtat tattaaaaga ttttgtatat ctacattatt
      421 tgtgattgcc tcatccaaaa taaataaatt atatgcatca tttaatgggt catgggcatc
      481 tccactaaac tctaagttaa caaattcaag taaatttttc aatgatatat agttcataca
      541 tctcatacca caatttatat atttttcttt tatatctaca aataaatctc taatgttatt
      601 tacaaacctt ggatggttat tttttttagc acttctcata tctgtgttat tgaaacatgt
      661 caaatccaaa ttaccaaaag tatatattcc tttaatatca gaaaatatgc caagccattt
      721 tttaaacttt ctcatgacct cttcataact tggtgcactc ttcaattctt cagaagatat
      781 atgtgttaat tcttgtatat gaggatacaa ctcctcatta cttactggtc ttattaaaga
      841 tttaaattta tcaatatttt ttgttttttc atcatacata actgctccga ttgcaattat
      901 atcagaatta aatactgctc tttttgattt agaatttggc atattcattt caaaatctat
      961 atatactctt ttcaatataa acaccctttc caattgttta tagtgattct ttttaactat
     1021 ttttattcaa aattttctaa gaaagaatgt ttctctccat ctttttgcca accaagtact
     1081 gaatcaagat ttacattttc tgccgcctta aatatagatt tttctacatt tttaaaattt
     1141 gattctaaac tctttattaa gtcttttatc tcatatcttt tattacctgt ttttttagca
     1201 gcaaccatac atgcacaatt taatggccat ataccactat tttgaataaa tcttataata
     1261 tgttcttctc ttatataata aagtggtctt ataattttta taccttcaaa attagtagaa
     1321 ttaagtttag gaagcattgt tttaaaattt ccagcacata ataagttaag cattgttgtc
     1381 tctattacat cgtcataatg atgacctaat gcaagtttgt tacaccctaa ttcttctgcc
     1441 tttgaatata atgctcctct cctcattctt gcacacatat agcatggata atcttttgct
     1501 atttcatctg ctatctcaaa tatccttgaa tcaaataaat gtattggtat atttagatac
     1561 tcacaattat ctataagtaa ttgtcttata tttgcatgat atccagggtc catagcaata
     1621 aattcaacat caaaattaac ttgtccatgt ttttttaact cttgaaacat tttagccata
     1681 agaatactgt cttttccacc agaaatcgct acagctatct tatcaccttc ttcaaccaat
     1741 ttataatctc ttattgcctt cataaactta gaccataaat ttttcctata tttttttatt
     1801 atactttttt ctatatctct tactggaagt ctttcctcaa aaggaactat aatttcacag
     1861 ccttttcctg atagttcact catctaatca cctcgtatat ttatgttaat aatattttac
     1921 aaaaaagtct accttcatcc acaaaatact ataattttta ctttaatttt actaaataat
     1981 ttatagttta caataacaca taaacttata ataacataaa taacctcttt cttttattat
     2041 cttttttatt tttctcattt aatattttat tattagtaac gatttttaaa tgattgaata
     2101 ttatacacta gatagagtta cctatctatt tacaacaagg aggttttcat cttggaaaat
     2161 aagactagag atatcaaaaa aaattgtggt ccatctttgg ctagaccata cattaataat
     2221 caaattttca cagaaatgta ctgcctttct gatgcattaa aatttggaac tatatttcca
     2281 gaactaaact tactagagtc tgaaatgtac aacaaagaat tatatgctaa gccaaaaaaa
     2341 tatagaggag gtagaagata atgaaagact catctagagc tgaacttatg agaaaagttc
     2401 aggaaacatc ttttgcatgt gttgatatga acttatattt agacaatcac cctgatgata
     2461 aaaatgctat caacacttat aattcattat gtaatcaatt tgcgcaagct agatatgctt
     2521 acgaaaataa atacggtcct ttaactaact ttgggtatgc tccaagtaga tgcccttggc
     2581 aatgggctga ccaaccttgg ccttgggaca gagaatttaa ttattagaca tcaagtattg
     2641 gaggattgaa aattcatgtg gatatatcag aaaactatac aacacccagt taatataaaa
     2701 acttgtgacc ctagaatggc taaatttctt ataactcaat ttggtgggcc aaatggagaa
     2761 cttgctgcat ctttaagata tttaagccaa agatatacaa tgcctactgg taatatgcgt
     2821 gcacttttaa cagatattgg tacagaagaa ctagctcacg ttgagcttat atgtactatg
     2881 gtttatcagt taacttctga tgcaagccca gaagagttaa aagctgcagg tcttggttca
     2941 aactatgctc aaaatggata tggaatttat ccaacagatt caaatggtgt tccatttgat
     3001 gtaagaccta tagcagttat gtcaaatccc gtaaccgatt tacatgagga tatggcagct
     3061 gaacaaaaag cacttgcaac ttattatcaa cttataaacc taacagatga cgttgatgtt
     3121 atagatgtat taaaattctt aggtcaaaga gaaataattc actatcaaag atttggtgaa
     3181 gctttaatgg atgcttacga gttagaagaa tctcaaaaaa tgttctaaaa tttttatttg
     3241 tataactatt attatttgat aatttataat ttactgttgt gttaaaattt ataaaaaata
     3301 taaatataat ttattttcta taaacagaga aaataaataa aaagcaggta tcaataaaat
     3361 agtaacatgt attatactat acattactat caatattgta cctgctttca tattataagc
     3421 aataaagaaa aatctattta ttaggtttta taataaaaca attataaaac tcttcttgca
     3481 tttacatatc tacttgaata gtagctacta tttatattag atattgttac tttttttgat
     3541 gaacctgaag atgcatgtat catatctcca tttcctatgt atattccaac atgacttaca
     3601 gaaccattat ttgaaccttg tgtatcaaag aatactaaat ctccacttct aaggtctcct
     3661 ctatttacat atgttccata cttactttgg tctctagata ctcttggtat actaacccct
     3721 gcagattttt tcataacgta ctgtgtgaat ccagaacagt caaaactatt tggaccttct
     3781 gctccccata catatggttt tccaagtagt gtctttgcaa aacttattac actatcagct
     3841 ccttgacttg gagaattagt cgaataagat ggaattgaag tatcaacaga acctttttca
     3901 gcaaggtatt gacttgacac atatccagtt tgattgccat aacttacttt tgtccatcct
     3961 ccactttcag aaatacttcc aacctcagta ccataactta atgtagctat tttagaatga
     4021 cttgtacctg gtcctgttct aacgttcaat gactttgctg ttacaacctt tgtacccttt
     4081 acaaggtcat ttgaactgtt ttcagcattt tcatttgtag agtcatttac actagttcct
     4141 aaatatttac ttgaaacata acctactcta ccattagaac ttatttttga ccatccattt
     4201 gactcagata tgtatccgac ttcagtccca tatcctagtg ttgatatttt agaactactt
     4261 gtacttggtc ctgttctaaa atttaatcct tttgctgtta caacttttgt cgacttaact
     4321 gaagtatcac tactttcatt gctacttcca aggctattta ttgctacata atttccatgc
     4381 acataacctg tgtttccatt atatttaact tttacccaag aaccttcttt tcctacgtac
     4441 tcaactttat cacctttgta aagtttcccc attgattcat ggtttgtacc tggtcctttt
     4501 ctaaaattta ccgcattccc tgttattgtt ctgctttcta tactcacact ctctacttca
     4561 gactcattag catatgctaa attccccata gtaggcatta ttatcgcagt cgccattata
     4621 ctggctgcta ttctcttttg attaaaattc ataactttcc actcatctcc tcttttctac
     4681 tatctttatt tcacttcaaa atataaaaga aataattgac actattaaaa tatcaattat
     4741 ttcttttata ttaatattat tacaaatttg taactatttg tctatagtaa catttgctta
     4801 ccataaatta ccatgtataa attttaatct ttaatagcct gtaatttagt aatatagcca
     4861 tcttttacct tttttaaaaa tggctatatt ttttaacttt tttgtaactt tttaaaatcc
     4921 agttgagcca aacccacctt ttcctctttc ggagtcactt aattctttta cttcttctat
     4981 gttaatatca tagataggtt ttactatcat ttgagcaatt ttcatatgct tttcaacctt
     5041 aaaatcattt ttaccatgat ttattaatat aattttaagc tctcctctgt atccttcgtc
     5101 aatagttcct ggtgtattta atacagtaac agaatgcttt aaggcaagcc cacttctagg
     5161 tcttacctgc gcttctgtca tagtaggaag ctctatacat atcccagttt tgataagttt
     5221 agtctctcca ggaggtatta caacctcttc tatagaatac aaatccatac cagcatcacc
     5281 tttgtgagca aaattaggta ttatagcatc atcatttaat ttttttactt ttaaattgta
     5341 catcttatat ctcctttcaa ctttctataa atattataac ttaaatttcg acctcttgaa
     5401 gttttttatt tttttgtggt aatataatta ttagtgtttt aaaggaggat tttttatgaa
     5461 acttgtactt gccgagaaac catctgtggc aaaaactata gcatcatttt taggtgcaaa
     5521 gaccagacaa gatggttact ttgaaggaaa tgattatata attacttatg cagttggaca
     5581 cttagtatca ttatatgata tgaaggatta tgataaagat aaatactctg gctcttggaa
     5641 aatgaacaat ttcccatttg ttcctgagga taagtttaaa tttaagattg atagttctaa
     5701 aactaaacaa ttcaacactg taaaaaagct tttgaataga aaagatgtag aatatgtaat
     5761 aaatgccact gacaatgacc gagaaggaga acttatagca tttttaatat ttttactggc
     5821 aaaaaataaa aaaccagtaa aaagaatctt ggtaaatgaa tggacaccag aagatattac
     5881 aagaggtata aaaaacctaa aagatgaaga tgaaatgaga aatcttcaag ctgctggata
     5941 tactaggctt attactgact ggttgattgg aataaatttc acttctgttg ctacattgaa
     6001 atatggaaat gggaaactat taaacatagg tagggtaatt cttccaacag ttaaattagt
     6061 ctatgataga gatatggaaa tactaaactt tgttcctaaa acttattatg aaatagaagg
     6121 gcattttaaa gctgaagctg gtgaatataa aggtaaatat gttaagggta aagaaagtaa
     6181 atttgataca cttgaagatg caaataaaat tatagcttca attacatctg aaactggtaa
     6241 aatactagat aaaaaagtta ctatgtcaaa ggaatatgca ccaaaacttt ttagtttgac
     6301 atcacttcaa ggatatataa cttctaagta ttccaatttt acatctgata aggttttaaa
     6361 tgtctgtcaa tctctctatg agggtaatgg taagggtgga tacataactt accctagaac
     6421 tgattccatt ttcttagaag aaagtttggc ttcaaaagct tctcaaactt tagataaatt
     6481 aaaggttggt cttgaatatg aaaataaaat taaattttct aaaactaaaa gagtttttga
     6541 ttcttctaaa gtagactccc atagtgctat aattccaact tatataattc caaaaagttt
     6601 atctaaggat gaacaattag tttatgatgc cataaaagat agatttgtag caaattttat
     6661 gcctcctgct gaatatgaga atacagaaat taagactgaa gtagataatt gtactttctt
     6721 aacaaaaggt aaggtgctta aatcaaaagg ataccttgag gtatataata aggaagaaaa
     6781 aaacgattta cttccacttg taaataaaga tgatgttgta gatgtgttag aaataaaacc
     6841 attaactaag caaactactc cacctaaacc atatactgag gacacccttt taaaggctat
     6901 gaaaaattgt ggtaaaaatg tgcctgaaga agatacaaca gtgctatctg gatattcgat
     6961 tggaacatca gccacacgtg ctgatgtgtt aaagaagata agtcaagtag gctatgtaaa
     7021 gaaaaaaggg aaatcttatt ctataacaga ccttgggaaa aatttagttg aaatttttcc
     7081 tgttaaagac ttatttgatg tagattatac tggaaaactt gaaaaaagtt taagcgatat
     7141 tcaaaaagga aagtatacaa gaaaagaata tcttactaat atcattagtt ttatatatca
     7201 aaatgtcaat attataaaac aagatgcttc aaaaaatata aacacagaag catatacttt
     7261 cgattcaaaa actaaaaaat ttactaaaac aaaagaaaaa aaacagaaaa aagatgtaac
     7321 taatactgaa aaagaagttg ctatatcaaa ggattctaat aacaaaaaag aagttaaaaa
     7381 tggtgatgaa aatcaatctc ttggcaaatg ccccatttgt caaggtgatg tactagaatt
     7441 tgataaaggc tttgcttgta aaaatcatag agaatgtaaa tttgttattt ggaaaaatga
     7501 taagtattta agtctttata aaaagaaagt taacaaaaca atggtcaaaa atattttaaa
     7561 aaaaggtgaa actaaagtaa aatctttaac tgctaaaaac ggtaataaat ttgatgctac
     7621 attaaaatat gataaaaatc cagatactgg ctatttcaat tggaaaatag agtttgacaa
     7681 ctaaatattc ataagaaaag aaatagcagt agtataataa tctatattat attactgcta
     7741 tttcttttct tatgaagttt taactttttt aatagtgact tttacaatca cactctaacc
     7801 taatttcttt actatttctg ataactttaa tgtatgttca tctaataaag ttagttcctc
     7861 ttcagaaaga ttagataatt tttttactag agattctttg agaatagctt ttactgcatc
     7921 aaataattta aatgctttat ctgttaattc aaccctaaga atccttctat cttttgggtc
     7981 aggaaattta ttgactaaac catgttccac taatctgtca ataatcggag tcatatttga
     8041 ttttaaaatt cctaaattag aagctatttg agaaattgat gatgaatttg atgtcataag
     8101 ataaagaatt accttagcat gtgatggagc cattggacat tcttcaaaat aagctttcat
     8161 tatatcagag ttattttgaa acttttttaa caaatcgctt tctttaaata tattattttc
     8221 aagcacaaat aaaaaatcta aaaaagagtc cgctatttta agtatattgt tgttatccat
     8281 atttgtaaca tcccttcaat agataatata ataaaacatt gttgtttaat atagtataaa
     8341 ttataaacta ttaataaatt taaaacaaga aaaagttatt gactcataat aattataaat
     8401 ttataatcaa attagagaat tataaattgc caataaaggg aagtttttta attagtctaa
     8461 aactaaactt aaattataag acactttaaa ttctacaaca agctagtgtg caatatataa
     8521 taggaggaga tatgaaaaga tatttaatag ttttcttaat gtgtagttca ctgtttttag
     8581 ttggatgtgg aaaaacagaa gaatctgaac ctgagaaacc aatagcagtt tctgttcaaa
     8641 aagcaatagg tggagaaatt gaaaacacaa attctttctc aggaactaca aaggttaaag
     8701 atgaaacagc tgttactgca cagactgttg gcacagttca agaagtgtat gtaaaacttg
     8761 ggcaaaatgt aagaaaagga gatgaattat tgagtataag cagtccagag ctagaaaata
     8821 gtgtaaagca aagtaaagcc tcactagatt tagcaaaagc aagttattca agtgccactg
     8881 gtggttcatt agaggcacaa gtaaatcagg caaaaacagc tcttgacaat gcaaagattc
     8941 aatatgagga gtctcaaaga aattatgaca ataataagat tctttatgaa caggaagtca
     9001 ttagtttaga ccaatttaaa aaaatagagt tttctttaga gcaaacaaaa caacagttag
     9061 attctgctca aagagcatac gatacagcaa cttcaaaaag tatacctcaa gctaaagcac
     9121 ttgctaaaaa acagcttgac caagctcaag tatcatataa tttagcaatg agtaatttag
     9181 acaaattaac attaacatct ccagtagatg gtacaataac agctaaaaac tttgattcaa
     9241 aggaaatgat aacacaatca caaccagctt ttattatttc taatcctaat atactagaag
     9301 ttgatttaaa tgtagcagaa tcagatatag gtaaatttaa gaaagatgga aatgtagatg
     9361 ttataattga agaccaaagg attttaggaa aaatagatta tgtaccttca gtagttgacc
     9421 ctcagacatc tttatatcct gttaaagtac ttgtaaataa tacaaacaac aaatttaagg
     9481 caggtatgtc tgctcaagta aacttaagtg ttgaaaaaga aaatggtgct gttacagtac
     9541 ctaaaaaagc aatatttgaa gaaaatggta aaaaatatgt atacatagca acaaaagaca
     9601 atatagcaaa gaaacacttg gttcaaactg gaattgtaac agaggataaa atagaaatta
     9661 aaagtggtgt aagtgataaa gatacagtga ttattggagg gataagtctt atttctgacg
     9721 gaactaagat atttcctgta gaaaaggaga agtagactat gaatttaaca cagacttccg
     9781 ttaaacgtcc tctcacaatc ataatggtct ttttagtatt aatagttttt ggtggtattg
     9841 gatataaaaa aatgtcaata aatctaatgc ctgatataga aataccagtt gtaatggtca
     9901 tgactacttg gacaggtgct ggtcctcaag acgttgatga acaagttagt caaaaagttg
     9961 atgaaagttt atctgccgtt tcaaatgtaa aatctactat atcaagttca caagaaagtg
    10021 tttctatggt agttgctcag tttgaatttg gaactaattt ggatgaaata atgaatgatg
    10081 ttaggtctaa agttgatgca ttacagacca gcctcccaga tgatgcagct aaaccaacag
    10141 ttttaaagct ggatatgaat gcacaggcta taggtcaact tgtcatatct ggaggaaatg
    10201 aaaatagttc acaagcctta agaaaatacg ctgaagatgt aattcagcct aaaatagaat
    10261 ccatagatgg tgttacttca gcagacctta aaggtggaga aaaagcacag gttaatgtaa
    10321 tagctgaccc agctgttctt tcaaattatg gagttagttt atccactata aaaggtgtct
    10381 tatcctctag taataaaaca ttcccttatg gttcaattac tcaaggtgag gataaaatag
    10441 ttttaagagc gattgataaa ttagaatccc tagatgatat aaaacagatt caaattcctg
    10501 taaaaggagg aaatacagtt agattagata atctttgtag tgtagattat ggatatgcag
    10561 acaaagatag tatttataga tacaatggaa aagacagttt ggtaatagat atttctaaac
    10621 aacaagatgc caacactgta aaagttatgc agagtgcata caaatacgta gatgaattga
    10681 ataaggaaaa tcctcaattt aaaattaaaa ttgctaatga tacaagttca tacataagtg
    10741 aatcaataaa cagtgtaatg agcaacttgc ttataagtgc tgttatcgca tttattgtaa
    10801 tatttgcttt cctaaaaagt gtaagagctt cactagttgt tgcagttgca ataccaattt
    10861 ctataatagg tgctatagca attctctact ttactggtga aagtttaaat cttattactg
    10921 caagttcatt ggtaatttca gttggtatgg ttgttgataa tgctacagtt gtaattgaaa
    10981 atatatttaa atataggaaa agtggcagat tgagtcttga tgattgtgct attgagggaa
    11041 caagaactgt aacaaatgca atacttgcat caacattgac cacaatagca atattcttac
    11101 ctatcatgtt tacagaaggt atagctaaaa taacttttgg ggcattaggt aaaacactaa
    11161 tagcttcact agcattctcc tttataggtg caattacact cgttcctagt gtatttgcaa
    11221 aattaagcag aggaaaaaat agtcaaaaga tgcaagaaaa agatagtcct atatttgata
    11281 aggtaagtga agcatataaa aaattattaa gtgtatgttt gagacatcaa cgcttagttg
    11341 taatatcaag tttacttatt tttgtagctt ccttatttgg aatgggattt ataggtatgg
    11401 actttatgcc tgcagcagac aagggtgaat tatctatttc tatagaactt ccaaaaggtc
    11461 ttagcctaga atccaatgat tactatgtat ctatgactga gaaaaaagtc tcagatattc
    11521 cagaaattaa aactttaata acaactttga catcagattc aaataatagt aaagcaagta
    11581 tagcaattga attagaatct caaaaaaata gaaaaagaac tactgatgaa atagaaaaag
    11641 agataattga tagagtggct actgtaccag attgtaaaat aaatgtaagt caaaacagta
    11701 gtgttatggg tggagctgga ggagcagact tcacattaga aatgaaaggt cctgatttag
    11761 atgtattaaa aatactggga aaagaagctg aaaaagaatt tagctctata aaaggattta
    11821 gaaatgttga aacttctctt acagatacaa cacaagaagc tcaatttact atagataaac
    11881 ataaggctca agaatatggt gtaaatactg ctgaaattgc aggcatgtta cgtacagcaa
    11941 taaatggtga ctccgtaacc actgctacta ttgatgatta caaagtggat gtaaacctaa
    12001 aatttaaagc agatactatt gatagcttag aagatataaa gcaactaaaa gtaaactctg
    12061 caactggaaa agaagttcct cttggtgctt tttcagatat aaaaatggca gatggtctac
    12121 aatctatatc taggactgat ggagattttt ctgtaaatat aactgctaca cttgacaatt
    12181 tagatgctgg tactgctaca aaactagcac tagaaaaaac gaataaaatg gtaattccta
    12241 aagattactc tataggtgtt ggtggtgaaa cagaaatgat gaatgaatct atggcaagtc
    12301 ttggattttc aatggtcata gctatagcat tagtttatat ggtaatggta gctcagtttg
    12361 aatcatttag taaaccattt ataatcatgt tctgtgttcc atttgcattc gttggagttg
    12421 tgctttcgct tctagttagt ggtcaaagtt taagtactgt cggtatgcta ggtataatct
    12481 tacttatcgg tattgttgtt aataatggta tagttcttat tgactacata gagcaactta
    12541 gaaaaacaaa tcgtaacaat gatttaattg gtttggtttc aattggttgt gcagcaagat
    12601 taagaccagt cttaatgact acagcaacaa caattttagg tatgttgcca acagcactat
    12661 ctcttggtga aggtggagaa actatgcaac cactagccat agttataatg ggtggtctaa
    12721 ctgtatctac acttataact ttggtgctta tacctactat atacttaata tttgataaat
    12781 gggaaaataa gttttcagac aaaatgccta aaatatttgg taagataaca gataaaatag
    12841 gaagtataaa acgtaaaata ataaagaaac caaaattgaa agctaaagtt taaatagaat
    12901 ggagggtgat tgtattgaat aaaaaaatga gcaaaatagt tgcaattggc tgtggtgttg
    12961 gtataataac tgccaattta atcccagttt acgcagataa taatacttct tctataaaca
    13021 aagttgataa ttctatttta agtgactcaa ataaaagaac atctgaaaag gaaattttga
    13081 ctgctagaga agctgttagt gctgcactta aaaatagtga aaaattaaaa atgaaatcag
    13141 aagaaataaa aatgttaaaa gaaaagttag aagtacaaga tgagtttgat agttttactg
    13201 gaagtgacaa ctcgtttcca tacgaccaaa ttggacttct taaaaatcaa agtgaacagg
    13261 ctaaaggctt tatggaggac caaatagcaa atgatattac taataaattt aacgatttag
    13321 tttcaagaga aaatgagcta gataaaataa aaaacaatct tgaaataaaa actaaagaaa
    13381 ttaaagatat gaaattaaaa aaagatttag ggttagtaac atctttagaa actgaatcag
    13441 ctgaacttga acttcaaaca ctacaaaata ctcaaaaagc taaacttcaa gaactaaaaa
    13501 acaatcaaga ctattttaag ttattaacta atatagattt aaataattat caattggata
    13561 aagaatatag atttgaatct tttagagtag gtggctcagt tgattcatat atggaaggta
    13621 aggttaatga atatttaaaa tacgaccaat tgattttaga acgtacagaa gaaagcttta
    13681 atgataaaga tgagaacaaa gcagatttac cagatagacc taaccttaca agaccagttg
    13741 ctcctacaaa accagagcaa ggtaacctaa ctgatgatga atacaaggtt cttatggata
    13801 agtatgaaaa agattatgat agatataaaa aagaagttga agcatacaat cttgaaagac
    13861 agacttatgc tgctggtctt actacttatg caaattatct tcaacaaaaa tttaatactg
    13921 aaaatggtct agtaacatta gaagacagta aaaaagctct taaaaaaggg ttaattgata
    13981 gctatgctca attacttgct ttagaagata caattcagat tactaaaaaa caacttgatt
    14041 tatcagaaaa acaattaaaa aatactaaat taagatatga tttaggatta attactctaa
    14101 ctgattataa aaaacaagtg gtaagtaatg aagatgctaa aaatagctat gactctctta
    14161 ttgtgaatta taactcacta aaaaatggta tagaaaaacc ttggatactt aattctggta
    14221 aatagaaaga ttactttaac atacgtttga ttaaaaaata gttatgcaca ctcgtggctt
    14281 tagtcatgga agattcagaa ggcaaataat agaaatagat tagtaaaaat atatttactt
    14341 ataaaactgt atacttttat agaggctatc tcaaaataga gataagcctc ttttttattg
    14401 tttaaattat aaaaatatat ttgattccat acaaaaagag tgccttatga actaaaaagt
    14461 tcattttgag acaccctcaa aagcttaact ctaaatttaa ttatttttta tcaaatgtct
    14521 catctatttt acatctcacc atgttaacaa attcagaaat attatatcct ctaagtttgc
    14581 atccacattt aggacaataa tccagtttcc tagataccaa agccctacaa ctaggttctg
    14641 gacatcttat ttttagactc tcatctgcta ctttaaatcc acatcgtggg catatactac
    14701 ctggacgtga tgatacttcc tttccacatt taggacactt tgtcaacttt atcccctcca
    14761 gtaaactcaa tttaattgat agttgaaatt tctctctaca ataatatatg caatataatt
    14821 aaatacgttt cacttacaac tatataagtt aaatttttat aataaaaatc ccctatattc
    14881 aatttacaaa tacttaattt gatacattga acaatagggg attttatttt tatttagtta
    14941 catattttgc agtctattat tatctaggat tttttataga tgcttgagct gctgcaagtc
    15001 tagcaattgg cactctaaat ggtgaacaag atacatagtt aagtcctaca ctataacaga
    15061 actctactga agatggttct cctccatgct ctccacatat tcctagtttt aattctggtt
    15121 taacttctct acctaattta gctcccatct taactaactt accaacacca ttttggtcta
    15181 gtacttggaa tgggtctttt tctaatattt cttcatctac atattgacct aagaatttac
    15241 cagcatcatc tcttgaatat ccaaatgcca tttgagttaa gtcattagta ccaaaactga
    15301 agaagtctgc ttcttgtgct atttcatcag cagttaaaca agctctaggt atttctatca
    15361 tagtacctac agtataagga acttctatac cttcttcttt tattatagcg tcaacagttt
    15421 ctactatcat ttttcttatt atttttaact catttacttc tccaactaat ggaaccatta
    15481 tctctggaga aactttaaca cctgctttga ttgcttctat agcaccttgt attatagctt
    15541 tagattgcat tacacatatt tcaggataag ttattgcaag tctacaacct ctgtgtccaa
    15601 gcattgggtt aaactcatct aaatcaacta ttctcttctt aatatcactt acttttattc
    15661 ccatagattt tgaaagttct tctatagtct catcatcatg aggcaaaaat tcatgtagtg
    15721 gtggatctag taatcttata ttaactggtt ttccatccat aactttaaat aactctacaa
    15781 aatcttctct ttgcattggt aatatttttt caagagcttt ttctctttgt tctactgtat
    15841 tagataatat catttctcta actgctggca atctagcttc atcaaagaac atatgctcag
    15901 ttctacatag acctatacct tctgcaccaa actctatagc tgcacgagca tctctaggat
    15961 tatctgcatt agttctaacc atcatacatt tgtgtttgtc tacccagttc attaattttt
    16021 caaagtttcc agtcaaagat acttctgttt tcttaacatc tcctaggtac acatttcctg
    16081 tagaaccatc tatagaaatg tattctcctt cttttataac tacatcatca agtgctctta
    16141 tttctttatt aaactcatca acttttattt ctccacatcc agcaacacaa catttaccca
    16201 tacctctagc aacaactgct gcatgtgatg tcattccacc tctagctgta aggattcctt
    16261 ctgctttaac cattccttct atatcttctg gagatgtctc tagtctaact aaaactactt
    16321 tttctccttt ttcatttgct tttactacat catcagcatt gaaataaact ttaccacttg
    16381 ctgcacctgg tgatgctggt aaaccttttg ctataacctt agcttctttt aatgccttat
    16441 cttcaaattt tggatgtaat aattggtcta attgattagg ctcaattctc atgatagctt
    16501 ctttttcatc aattattcca gcttcaacta aatcaaccgc tacatttatt gctgctgctg
    16561 ctgttctctt accatttcta gtttgtagta tatataatct ttcattttct atagtaaact
    16621 ctatatcttg catatcttta taatgacctt caagtatatg agtaattttt acaaattcat
    16681 cgaatacagc tggcattaca tctgcaagag ttgatatatt ttgaggagtt cttatacctg
    16741 caacaacgtc ttcaccttgt gcattcatta aaaattcacc aaataattta ttttctcctg
    16801 tagctggatt tctagtaaat gcaacacctg taccactagt ttctcccata ttaccaaata
    16861 ccattgattg aatatttact gctgttccta agttatgagc tatatcattc aatttacggt
    16921 atacgattgc acgaggatta ttccatgatc taaatacagc ctctattgca agcattaatt
    16981 gctcttttgg gtcttgtggg aaatcatttt ttatttcttt tttataaatt gctttaaatt
    17041 cttttactat ttcttttaaa tcatcagttg taagttctgt atcaactgtg tatccctttg
    17101 cttcttttac tctgtctaat acattttcaa atttatattt tggaacttcc atagcaacat
    17161 cagaaaacat ttgtatgaat cttctgtaac tatcatatgc aaatctttca ttttgtgtag
    17221 cctctgctaa gccaacaaca ctattgtcat taagacctag gttaagaatt gtatccatca
    17281 ttcctggcat agagaatact gcaccagaac gaactgatac taataatgga ttcttattgc
    17341 atcctaatgt tttatttaag tctttttcta aagtagctaa atgctcttct atttctttta
    17401 ttatctctgc tcttatactt tcattgttaa cataataatc attacatgct tctgttgtta
    17461 tagtgaatcc aggagggaca ggtaagccta tcttagtcat ttctgctaaa ttggcacctt
    17521 tacctcctag taaagatttc atgtctttgc ttccttcacc aaaactataa acatacttag
    17581 tttccattgt taaatccccc attaatcttt ttattttaat ttatatcatt tttattaata
    17641 gacattatta aatttctatt tctttgtata tctttagacc attttctttc attatgtcta
    17701 aaattatacc tgctgtttct tctattgcct tatttgaaac gtttattact gggcatccaa
    17761 ttcttttcat tatctcttct gaataatcta actcctgaag tattctttct aaattagcgt
    17821 agtttgcttt actggacaat cctaaagctt ttaatctttg ggttcttatc tcattcagct
    17881 tttcaggtga attagtaaga cctattatct ttttagtatc tatctcaaac acttctttag
    17941 gaattggtat ttctggaact aatggaacat tagctacttt tatattttta ttagctaaat
    18001 acatactcaa aggagtttta gatgttcttg atattcccac taaaattatg tctgcttgaa
    18061 gaacacctct agggtctttt ccatcatcat atttcactgc aaattctata gcttcaactc
    18121 tcttaaagta agattcatct aattttctaa ttataccagc ttctctttta ggttttcttc
    18181 ctgttctctt gcttatttct cttagtatat ctgtcattaa atctatacaa ctaagacctt
    18241 ctctttcgca atatctttca acaatactgc ataattcttc atcaactaat gtatatacaa
    18301 ttaaagcgtt ttcagctttt gcattctcca aagtttcaag tagtactcct ttattaatca
    18361 tgtatggaaa tctttttatt tcataagttt cattcacata aaactgagac atacatgcct
    18421 ttgcaacttg ttgtgcagtc tcccctactg aatctgatac tgcatatata attaggtttt
    18481 tcaccagcat acctccttaa ttgtcaacta tttctaagaa tagcttagtt atgttggttt
    18541 ttgatattct cccaacaact ctcatatgat ttttgtcttc tcccttatat tcaacaatcg
    18601 gaatcgaatc tacttcatgt tctattattt ttcttgaagc taataaaaca cttgctcctt
    18661 tagttaaagt gactacattt ggagttcttg tcattatcat acctattggc attttattta
    18721 tatcagaacc tcctatagtt gcttttagca agtcttttct ggaaacaact ccacataact
    18781 cttcattctc atctataata actatactcc ctacatcaga taaaaacata gtgactatta
    18841 catcatatat actttcatcc ttcttagcta gtacaggcat gctcattata tcctctactg
    18901 ttttttcttt tacactttta ccaattaaat ttatttcact aactcctgaa taaaaatatc
    18961 caacttttgg tcttgcgtct aatattcctg tcattgttaa tatagctaaa tcagatctaa
    19021 gtgtagcacg agtcacattc aagctggagg caatactttc actcgttatt ggttcatttt
    19081 ccttaactat atctataatt tttagttgtc tttcattaag ctgaataata atcaccttct
    19141 ttcattgtgc tatacttttt atcttttcgc atcttatata gtatattata taactatata
    19201 taccattctg taaacagatt ttttattgaa tacgatatat tttttactaa gttctctcgc
    19261 ttaaagatat ttattatata ttaatggggg atatttcttt aattaataga actatattag
    19321 tattacagtt aatattataa tacataattg gtcattttaa ttcattttat attaaaattt
    19381 ttaataatat tatttcaatg tgaatataaa attgcagaac taattcaaaa taatttttac
    19441 gactacaaat aacctataat atacttttaa agaaagtatc ctaacaagaa tatataaaaa
    19501 tttaaaaggg ttgatttaaa aataaccatc aacccttttt actaatatct atttatatta
    19561 ccatcaaatc ttacccaaat attttttctt gcaattgtct taaatgatat aaagtagtat
    19621 ctttttctat ctctaccata tcgtaagtta taacttcacc ttttttaata tcttttacaa
    19681 ctttagtctt tttacttatc aaaccaatag gtacagcatt catagccttt gctacatcgt
    19741 atttttctat agtaccatag catgtatatg ctccatagcc atccataaac tcaccttttt
    19801 tcaaatcttt cttagctata gtcataactt ctgctactag tccagcttta ggtactattg
    19861 tagccttatg gtctaaaact gccatagctg ctgataaagg agtctctaaa ctacataaat
    19921 gatatggtct atataatatg taattaggtc catcacccat acttaaatat tttagttcat
    19981 cattaactgc ttttaattta tgggctacta ctacgaaaac tccaggtgct ataccattta
    20041 caaaatcaac tacaccgtaa ttatctaata ctccaccttc gctttttaat gcatatttct
    20101 taggtacttc attaactgta gcttcaatac catgaccacc tcttacatca ggcacaaatc
    20161 cagttgcatt acacattaaa gccatttcta ccattgtttt agttccttct ttaaaagaag
    20221 ctatcatatg aggtgaagct ccttttcttt ctgcttcttc tctaactgta tcaggattac
    20281 aatctaaatc taatttatta tttttacctt tacctatcac tctaacttca aaccccattg
    20341 catctgcaaa atcaaataat tccattactg cacctggctc atctcctgca gaacctgtaa
    20401 atattactcc agcatcatct gctaattttt taagtattgg tccaacaaca caatcagttt
    20461 cagcatttaa cataactata tgttttttat ttaaaataga gtttaatgct atctctgcac
    20521 caattgcaat acccccagtt gcatctataa ctacatctat tgacttagtt ttacaagcca
    20581 caagaaagtc attacatgtc aatacttttc cttcttgtaa ttttatttct gcatcctttt
    20641 catttgttac attatctata atttcttcat ctattcctgc atcagtaaaa gctttatgag
    20701 ccaactccaa atttatatct acaacaatag aagcttcaat acctttcata tttgccattt
    20761 ggcttaccat tccatttccc atatgcccag ctcctataag agctactttt atttttttac
    20821 cttcctcttc caattttgca agttttctgt ttaaatctaa cataccaatt cctcctgtta
    20881 taataatttt attttcaaat taagaaatag ttattaaatc tccaatagtt atatctggat
    20941 ttcctatttc cacatgtatt tctcctggta aatttacttc acattttcca tcaaatttga
    21001 ttgtacaatg cccaatttct ctaagagtct tctgagcaat atcaccaact gaaactatac
    21061 aataatctct attccctata gtaagtgtat ctcctatttc aacatcactt tttaacgttg
    21121 ctattgaatg aattacagat atatccttta agtcgtcatc attaatggtt tcatcatata
    21181 taataagaca attgctttca tccattaact ctttaactaa actgcctatc ccacttatct
    21241 taacttcata tttcatgaca ttcctcctga taatttatat ttatattgag ttaattaaaa
    21301 gaaacattta ttttttcttt tataaatttt atagcttgta caatactctc ttcatcttta
    21361 aatttttgct ctgcactata tatatctaat ccttctattt cttcaatctc tttaaattta
    21421 gccattactg tacgcccttt taaaatttct ccaaacttta taaacccatc tgaatctgaa
    21481 gatataacgg ctatacttcc tttagaaaaa tagcttttct ttttgcctgt agacactata
    21541 tcaccctttt ttttagctct atttaaagtt ttaaaataca atttattctg cttcattata
    21601 aatatagtat ttaaaatata agcaacaaat aaaattacta ataatttcat atttatacac
    21661 cttccaaaaa tcacattatt tttaaatctg tataacaact ataaatgctg tacaatagtt
    21721 atataaggtt tttaagtaac acctttttaa attctaaaaa agttctacat ttacttatct
    21781 tattcgttaa ttttacatct tggcctatct ttaaaacttc ttcataaatt tttactaata
    21841 agtctgagtc tatcttattc tcacatggaa acattgtcat aagaattatt tttatacttc
    21901 tatttgcata ttctattggt tcttctaaaa ttccaactgc cattaaaaac ttatctgatt
    21961 tttcatttac agaatgagga aataataaac ctttatcaaa tactgtggga gatttttctt
    22021 ctctattgac tatatttttt ctaaacttct catcaataca tcccaaatcc ataagatggt
    22081 ccatcatttt ttctaatgag gcaagtatag tcttttcatt taatatcata aatttatctt
    22141 catctaacaa attattgatt agtaaatttg tagaattagt agtgtcaata ttcccttctc
    22201 ttaggcacaa tactgttttt aattgttctc ttagtttgtt ttcatcaaat attgtattta
    22261 tttttaatac tattgtattt atatttgatg tgtctaaatc aatagttgta aaaactatat
    22321 cgtattcatc taagttaata tttctcaaat taaaacttga aagagtatca attttaggat
    22381 tatttcctat cagtttttct actcttattt tcaatagttt tgctgttcct agacctgtac
    22441 tacatataat tgctattttt tttattgaat agaatctact gctatttctt tctaaatatc
    22501 cactgaaatg gattgctata tatccaatct catcttctga aacttctaag ttatactttt
    22561 tctctattac ttttcctgct atttgtgcta atttaaatgg aagtatataa ttttgcttaa
    22621 tctcttctaa caaaacattt tttaacttta tattaaataa tagcctgttt aaagtaaaac
    22681 taagatgata tcctagacct actcttaatt catcctcatt tataaaaata cccatatcga
    22741 catatatttg attaaatata ttttccatca actcatcaat gtttttacta attctactac
    22801 tatttaaagc acattctgat gctggtgcat ttccactaac taacggtata gttaaataaa
    22861 taatttcttc atcatttaaa gtacattcaa acattcctga tattatatgt tttatttccc
    22921 tagcaataaa gtattcatca tatgatttaa gtaaatcaaa ctttacatca taatctttta
    22981 ctttcttttc ttcttttact ctatagacta aaactactat gtagttaata acttctctta
    23041 acatttcatc tgtaacataa aaattatttt ttttaaataa agtcaatagt ttttcttcta
    23101 aatttatgat ttcttctttt ttgattcctt taaaatactt tgaattactg aaatcttttc
    23161 ttgagttttt atacaactga tttaatataa acagtctaat atcaagttca tttccattta
    23221 atttcatacc tgtattctgt tttttaatca agtttaaatt atatgaagcc aaaacttttt
    23281 ctacatactg gaaatcattt actaaagtag ttcttcctac acatatctca tcagctaaac
    23341 tatcaagtgt aataaatcca tctagttcta tcaagtaatt tagtataaac tctactctat
    23401 cttcttttga atttaatgaa aatacatttt ttctattcat atcaataatc ttattgagta
    23461 tctgctcatc ttttatttct agtttatagc cttgaccctt tatatatttg attactgcta
    23521 tatcattacc taaatcttta ttcaattgtt ttatatacgt ccttacactt ctagttgtga
    23581 cattcaattc atttgctatt gagttaatac tcacaaactc ttttttacta cacataatca
    23641 atatcttaaa tatcttgcgg tcaatagaag gaattttctc agttacactc attttgtatc
    23701 tcctccttga tttcattcta gtacaaattt gaaaccaaat taatacataa aatttcactt
    23761 taataaagga aaatttagta ttaatctaac tcgataatta cagctaatta atagtataaa
    23821 agctagtctt tcattaacaa aaaatcttga ctagcttaaa tttatattta caattttatt
    23881 aattaattcc aagccttata ttgacattaa atattatctc aatgcaaata ctgcaactcc
    23941 atatgcaata ataacagcta ttggaccagt tattaaacga gagtaaaata aagctggaac
    24001 accatactct acagtttctg gttctgcttc tcccaaactt aatcctactg gtacaaaatc
    24061 acatccagct tgcccattta ttgcaaataa agctggaagt gctaaatatg ctggtattgc
    24121 accaagacca atttgtgtac ctacaagagt ccctactact tgagctataa ctgcaccagg
    24181 tcctagtatt ggtgataaga atggaagtgt gcaaattact gatataatca ataatccacc
    24241 aatattacct gcaagtggag atataactct tgcaatccag tctcccagtc cagatgctaa
    24301 aataattccc ataagcatac ttacaaatgc cataaatggt attacgttat tcattaccat
    24361 ttggatagta tctcgacctg catcataaaa ttttgatact acttgccctg ccccttgacc
    24421 aatagaaagt attatgttct ttttagcata ttcaccttgt gcttttgact taacctcatc
    24481 ataattatca ggctttctaa tagaactctt attttcgctt ttattttctt gagatttttg
    24541 tggcatatct tccccatcta caacacttat acagttagga ttaacatctg atacataata
    24601 ttcttctgtt ataaattttg ctaaaggacc tgtttttcca actggattta catttattgt
    24661 aggtattttt ttctttggat aaactccaca tctagcagtt ccaccacaat caataataac
    24721 tactgctact tcttcatcag aaactccagt tttaaatcca tctacaattt cacaacccag
    24781 tagttctttt atttttaatg ttacttcatg gataccacca gcagtcattg atagtatctt
    24841 atttctattc ccttcttttt ttatatacaa aggacctccc cagcctgaag ttcccttttc
    24901 tatttttaat attttattct cctccatttt atctacctcc taagccttat ttgttgctct
    24961 attttttctt gttagaaaag catacatttt ttctgttact atacctctta taaaaattac
    25021 aattagacca actataaaat accacaatgc caatgtagta gtttctttac ctaaagtagt
    25081 caaacctgca gatattccca accatacaaa aagttctcct gcatttgcat gtggaaaaag
    25141 acctgtaatt ggatgtacaa atgaaactgc tgcatcataa aatcctgctt tgtgctcttc
    25201 ttttaaaaat ctaccaaatg tatagcacat aggatttccc aagaaaaata ctgatactaa
    25261 tggaagtaga atatatcttg taaaagagtt ctttcctagc ttagaagccc aattattaac
    25321 tctttcctca ccaattatct taatcaaaga gttaatagct accattaata caattagcgt
    25381 tggaagagta cctgaaacaa gacctataaa ttgttctccc cctttctgaa acaaaccgat
    25441 aaaccactct gcacctttac ttagacctgt aataacgttt tccataaaat tataacctcc
    25501 ctataatatc tttaaatttt taattttact gcttaccata aattttacaa attacatctt
    25561 ttttctgtac tatatgctaa tattgtaaat gtttttttat taatatcatt ttaatataat
    25621 atttttgata aataaata
//
LOCUS       DAEOTL010000050        25570 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.050, whole genome shotgun sequence.
ACCESSION   DAEOTL010000050 DAEOTL010000000
VERSION     DAEOTL010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25570
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.050"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            100..330
                     /locus_tag="KRH82_002477"
     CDS             100..330
                     /locus_tag="KRH82_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655750.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSIIGSIFYFCKDLLNHKIKYVLIRD
                     IFVNRITYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            387..1037
                     /locus_tag="KRH82_002478"
     CDS             387..1037
                     /locus_tag="KRH82_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBG8655751.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1251..1922
                     /locus_tag="KRH82_002479"
     CDS             1251..1922
                     /locus_tag="KRH82_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655752.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKE"
     gene            1919..3049
                     /locus_tag="KRH82_002480"
     CDS             1919..3049
                     /locus_tag="KRH82_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8655753.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKIRMEQVV
                     ENLIINAKKHVVYNGNLDLSITCENGLLLFKIYNDGRIIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3464..4309
                     /locus_tag="KRH82_002481"
     CDS             3464..4309
                     /locus_tag="KRH82_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655754.1"
                     /translation="MIKVEELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4309..5337
                     /locus_tag="KRH82_002482"
     CDS             4309..5337
                     /locus_tag="KRH82_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655755.1"
                     /translation="MYSKFFTLVKKEFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDDYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFLICDLCFTVLLVV
                     FNIGFFEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5340..6353
                     /locus_tag="KRH82_002483"
     CDS             5340..6353
                     /locus_tag="KRH82_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655756.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(6881..8131)
                     /gene="cme"
                     /locus_tag="KRH82_002484"
     CDS             complement(6881..8131)
                     /gene="cme"
                     /locus_tag="KRH82_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBG8655757.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8217..8963)
                     /locus_tag="KRH82_002485"
     CDS             complement(8217..8963)
                     /locus_tag="KRH82_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8655758.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9116..10138)
                     /locus_tag="KRH82_002486"
     CDS             complement(9116..10138)
                     /locus_tag="KRH82_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBG8655759.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10138..12558)
                     /locus_tag="KRH82_002487"
     CDS             complement(10138..12558)
                     /locus_tag="KRH82_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBG8655760.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSNKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLSAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPKSLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVYFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKALKENP
                     KSITGRYL"
     gene            complement(12644..13564)
                     /locus_tag="KRH82_002488"
     CDS             complement(12644..13564)
                     /locus_tag="KRH82_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8655761.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            14154..15080
                     /locus_tag="KRH82_002489"
     CDS             14154..15080
                     /locus_tag="KRH82_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBG8655762.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(15440..17092)
                     /locus_tag="KRH82_002490"
     CDS             complement(15440..17092)
                     /locus_tag="KRH82_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBG8655763.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTKQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            17691..18812
                     /locus_tag="KRH82_002491"
     CDS             17691..18812
                     /locus_tag="KRH82_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBG8655764.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            18848..19261
                     /locus_tag="KRH82_002492"
     CDS             18848..19261
                     /locus_tag="KRH82_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8655765.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            19254..19793
                     /locus_tag="KRH82_002493"
     CDS             19254..19793
                     /locus_tag="KRH82_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8655766.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIEADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(19993..20478)
                     /locus_tag="KRH82_002494"
     CDS             complement(19993..20478)
                     /locus_tag="KRH82_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655767.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            21383..21760
                     /locus_tag="KRH82_002495"
     CDS             21383..21760
                     /locus_tag="KRH82_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBG8655768.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            22156..23961
                     /locus_tag="KRH82_002496"
     CDS             22156..23961
                     /locus_tag="KRH82_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655769.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            24038..24577
                     /locus_tag="KRH82_002497"
     CDS             24038..24577
                     /locus_tag="KRH82_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HBG8655770.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            25191..>25570
                     /locus_tag="KRH82_002498"
     CDS             25191..>25570
                     /locus_tag="KRH82_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBG8655771.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKLLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGN"
BASE COUNT         9388 a         3110 c         4059 g         9013 t
ORIGIN      
        1 tttctatact ataattattt aaaactaaat ataaatgttg gaattattta ggacttgaaa
       61 ttgtctaaaa ataaatataa gtgatgaaga ggtgatgtga tgagattaga tatggatagt
      121 atgttatatg tactaattta tatgacatta ttggtatcta tcattggaag tatattttat
      181 ttttgtaaag acctcttaaa tcataaaatt aagtatgttt taataagaga catatttgta
      241 aatagaatta catattctga agaacggttg cctaaacagt atatagtttt tcagaaatat
      301 gatatttgga ggtattgtag tttgttttaa tttgaaatga atctattata aattctaaag
      361 tttaaaaata aaaaggagag aataaaatgg atttcatttc aagtatattg caaggattat
      421 taagtatatt atttaatttt acaggtgatt ttggaatttc tattgtactt ataactttaa
      481 tagttaaatt agtacttatg ccactatcat taaaacaaag attttctgta aaaaaacagc
      541 aagaattagc tgaaaaaatg gaacatataa aagaaaagta taagaatgat actaaagaat
      601 tggaaaagca aatacaagta agttctgtag aaagtatgaa gagtatgctg ggatgtctta
      661 tagttttggt tcaaatgcca gtagtatatg ctttatatca tgtatgttta gatatgacaa
      721 aggaatttac aacaattata attccatgga ttgctaattt aggtacattt gataatttgt
      781 ttatattacc ttgtatatat acattaatta tgttagcttc aaatttagtg aattatatac
      841 catatttaaa aataaattct caagtaaagt ttaacaaaca aatggctgtg gtgactacca
      901 taacaagtct tatactaact gttagaactc cagtagccat aggtctgtac tttataacaa
      961 gtgcaattta ttcattaatt gaagatattt gttttagaat atattttaat cgaaaaaata
     1021 gaatagtgac aaaataatat aattattatt agaaatattt tagcctgcta acatagaaaa
     1081 agttagtagg ctatttttat ctatgatatc aattccatta agaatagtct aaaaaatact
     1141 atcaaaatgc tataaaaaat actatcaaaa tactataaaa aaatagttga aaaataaata
     1201 aattaatata aactaaaata aagcctacaa aaaagaggtg ataaatagaa atggctaaaa
     1261 tactaattgt agaagatgaa aaaaggatgc aaagtattat tgtagaatat atgcaaaagg
     1321 gaggatatac ttgtataact gctgatgatg gagtcgaggc acttacaata ttaaagagca
     1381 acaatataga tttaatgata ttggatatta tgatgccgta tttagatgga ttttcagtgt
     1441 gtagagtttc acgtgaaatg actaatatac ctattattat attgacagct aaaggtgaag
     1501 aggaggacaa attaaagggt tatgaatatg gcgcagatga ttatataaca aaaccattta
     1561 gccccaaagt acttttagca aaagttaatg ccttgttacg tagatacact actgatattc
     1621 ccaaaaattc attgagttta ggaaagattt ttattatggt agcatcaagg caagtgtatg
     1681 tagaagataa attgattgat ttaacatata aagaatttga attattgcgt ttatttatgg
     1741 aaaaccctaa tcaagttttt tccagagaga aacttttaaa ttgtatatgg ggatatgatt
     1801 ttgaaggaaa cacacgaact gtagatacac atataaaaac cttacgcaaa aagcttggta
     1861 gtgaaggaca ccatatagtt acattaattc gttcaggata taagtttgag gttaaggaat
     1921 gaatagttta agaaagatta tagaaaaact gaaaaatgta gatatttcaa attggattaa
     1981 acaaaatttt ggactatatt cagttagaaa aaaagtgttt ttactttcta aattatcagg
     2041 agcgttaatt atattatttt atctggttgt tgaagaattt tcgataaact ctaaatttga
     2101 attttggatt tggtttataa tactggttat atttattatg agtattgatt tcttattggg
     2161 aaaatttatt tcagaaccaa tcacatctat aaataaatct gcaaaaagta tgtcccaact
     2221 tgatttttct aatccatgta ctgtaaatac taatgatgaa tttggagaac tttctaggag
     2281 cctgaataca atgtctacaa atctacaaca ggcattatca gacctagaaa gtgcaaatat
     2341 tcaacttgaa aaggatgtaa ataaggaaag aatgctattg gaacaaagaa aggagttggt
     2401 agatacaatt tcacatgaaa tgaagactcc acttggcatt atacgtgcgt atacagaggg
     2461 gcttatggat gaagttgatg aagaaaaaaa gaaaaattat atgaatgtta taatagaaga
     2521 aactgataga atgaacaata tgattgtatc attattagac ttatctgcat tggaagcagg
     2581 agtttctaaa cttaacccag agcgttttga ttttatagag tttgttgaaa ctgtggcagg
     2641 tcgtctttta attgatatac cagatgccaa tttttatttt acatatgatt tgccagagta
     2701 tgaagttttt gtagtggcag ataaaataag aatggaacaa gtagtagaga atctaattat
     2761 taatgcaaag aagcatgttg tatataatgg taatttagat ttatcgatta catgtgaaaa
     2821 tggcttgctt ttatttaaaa tttataatga tggtaggatt atagagcaag atgagatttc
     2881 aaagatttgg tctaagtttt atcgtagtgt tcaatctcag cgtacaggag gttcaggtct
     2941 agggcttgca attgtttcac aaatacttac aatgcaaggg ttagaatatg gagtgaataa
     3001 tcgtgataga ggagtagagt tttattttat gattccaatt gatgaataat ttagtattaa
     3061 tttataaatt ataagtatct gatgtaaaat atttttcttt gtagacaata gatatctaaa
     3121 gagaataaaa taaaaaagtc taataaaaaa atttaataaa aagcttaatg agaagtcttg
     3181 ttttcctgat gaaaacaaga ttttttatta agctttttat tatttcactt cgatttcaca
     3241 agagagacac tttgatttca ccaaatagaa ataaaataag ttaaataaat taaaaaaata
     3301 taagaagtaa ttaaatacgc ttacaagggg gggcacttat gaaatggtat acatggttga
     3361 ctattatatt gataatattg gtttctattc cgcttaaaat taaatttata aaatggtggg
     3421 atagacgaca aaaagaaaaa aataatgaag gaggctatga tagatgataa aagtagaaga
     3481 gttgaaattt tcttatggaa aagataaaca gatattgcat ggacttaatt ttgaagtaaa
     3541 agaaggagaa atatttggat ttcttggacc taatggttca ggaaaatcca caacacaaaa
     3601 aatcttaaat ggtgttttaa aaggttacaa tggtcatgta tccatttttg gtaaggaagt
     3661 taaagcatac acagaatctt tatatcaaaa gattggtgtt ttatttgaat ttccttattt
     3721 atataccaat ttaagtgcaa ttgataattt agaatatttt tcgtcttttt atcctaaaaa
     3781 tcaaaggaga gatatatatg aactcttaga tttgttagag tttaagaaag agtttataaa
     3841 taagcctgta tcatcctact caaaaggtat gaagcaacgt attagtatgg caagagcatt
     3901 ggtaagtaat ccaaagttgt tatttttaga tgagcctact agtggacttg acccatctgg
     3961 agctgtacta tttcgtaaga ttattgaaga agaacgaaaa aaaggaacaa ctatcttttt
     4021 gactactcat aatatgctag atgcagattt aatgtgtaac aatgtggctt ttattgcaga
     4081 tggaaagatt atggtaatag ataaacccaa aaatttaaaa atgaaaaata gcaataataa
     4141 agttgaagtg gaatttgtat ataatggaaa tcgagatatt gaaattgtag atatacaaga
     4201 gttagaatct ggaataactt ttaaatatga tgaaatctta agtgtacatt caaaagaacc
     4261 tacactagaa gaagttttta ttaaatacac aggaaggatg ttagtgtaat gtactctaaa
     4321 ttttttacct tagtaaaaaa agagttttgg atgatgattt atggtaaatt ttttgtgctg
     4381 acacttggct ctctcatact ttattcgtgt tatattaatt ttggttatgt aaagtttatg
     4441 gatgaagata gttatcacaa taatgtatat ctatataatc cagagaatat aagcatgagt
     4501 gcatctccat taattaatca agtttcttct ataggtgaat taaaagcaaa acttgatgaa
     4561 gatacaagtg cagtttgtat tgatatgagt tccagtaagc cgaaagtaat tttacatgaa
     4621 agtattaaag gagttgacga ttatagagct gactatgcat tgtcattatt atcatcagaa
     4681 aaagaccata atagcaaaat atcagacaac aatgcaataa ttcaaattaa tgataaggat
     4741 acatctgaga taaaacaaag aaaagacatg acttgtgaga ttttattctt tgaaattgta
     4801 gctattggat ttttagggat tgcctcttta ttatttaaag aaaagcagat gggagtaatg
     4861 cgtattactg gtattttacc tgtaaaaaga agtcttttta tattatcaaa gatatttgct
     4921 tttttgatat gtgacctatg ttttacagtt cttttagtag tatttaatat tggatttttt
     4981 gaaggaataa aaatacttcc acaagtatta gttcaagcta gtattttatc aattattatg
     5041 tctttgattg gaataggatg ctcaatgtta ttgagagatt ttaagcaatt ttctcttata
     5101 tatcttgtgg ttgctgtatt cataactaca cctatatttc tatctgcaaa tacatctttt
     5161 gaaatagatt ggattaaata tcatcccttc tatcatgttt atagtcagct taaaaatgcg
     5221 tttttcatga atttttcaaa agaattagtt tattttgtag tgtgttcttt gacaataata
     5281 gttctatttt tacttgtaaa atatattttt aataaagagt tggttaggga gggataatct
     5341 tgataggatt acgttaccag ttaaagagta taaaaaaaga taaaatgtgt ataatttcct
     5401 tctttttacc agttgttatg gcgattttaa taaattttat gggaacaatt gatatatctt
     5461 cattagggga gatacgtttt ggtatagtga aggatacact tcctgtacaa acagagcagt
     5521 ggttgaagaa gtatggtatg gtaagtgtat atgacacaaa aatgcattta atacgtgaaa
     5581 ttaaggatat taaaacggac acaattggag ttgttagaga tggtaaaggg ataaaaactg
     5641 tgctttatgg aaatgagatt aatgctataa aaaatgttgg aaagacattg ccagagatgt
     5701 ttagactaaa gggtgattta aaagatgttg aggttacaat attgcctaaa gatagtattt
     5761 taaaagagtt tcaaaatgtt tttattgcca tgattttaat tactgctatg tttatgggat
     5821 gcacctttaa tgcaatgaat attatatctg aaaaagaaga tggaatatca tttataaatg
     5881 aagttttgcc acagagtaga agtcagtata ttatacaaaa agtatttttg ggtcttttat
     5941 gtgggtgttt atcttcaatg ataactgtat ttatatgttt ggatatttca atattagata
     6001 tgataatgat gttgttactc gttgtatttt cagcatttat ttcatcactt ataggtttat
     6061 ttattggaaa gttgtcagaa ggtcttatgg taggaattgt ttatattaaa atagtaatga
     6121 ttttatttat aggtactcct ttgttaatat atcttctagg ggttaatacc agtggtatag
     6181 ggaatttatg ctatataatg ccttcagttg ctacatttaa tggtattatg gagattatta
     6241 atggtaatgt cattattatc aaagatattg taattttggc tgtacattgt gtagtatggt
     6301 ttatgatata tattatttta gataaaaaaa gaaagttatc ttttagtaga taactcagta
     6361 taattataat tgggacaatt taataggtga tttaatatac tttgtatagt gtaatttatg
     6421 tagtgcaatt tgtatacttt aatttatgta gtgtaatagt tagttttatt ttataattat
     6481 tcaatataat ttagtaagaa gttcagtaca attagagcta cttagtggaa aacttaatag
     6541 gtacttaaac tatataaata ctttattttc ctccatttgt actataaatt taatttatga
     6601 tataaatgga ggtattatta tatgatttga taaatttcat cattataacc tacaagtaaa
     6661 ggtattatta tataaagtta ataaagatag tatcaaaata ttatttgcta taaagagagg
     6721 gactcaaaat aaagataaac ctatttttca atgttgaaat gataaaatat atttaatttc
     6781 atataaaaaa ttttcttcat aaattaaaaa gtccatttta agcccccctc agcccccctc
     6841 atttttaacc agataaatcg agttaaacta tttaaatata ttactcggat tcatttgact
     6901 tagatattcc ttgcttgtaa aattgttttg aataggggat agccaaagca aaaaataaaa
     6961 gtataatccc tgctatgatt attaaattat taatagaaat tacatctgcc attggtccga
     7021 aaatcatcat accaagagga ataaaaccag tatatataat aataggtaag ctaagaactc
     7081 gacctagcat ttgtggtgct acatgctctt gcaacatagt catagctgat gcttgaataa
     7141 ttggaattga aaaattcgta aaaaacataa atataaaaaa ttgccaagct tgtgttacaa
     7201 gacctagaat aattgaaaaa atagcatagg ataatattgc tagaaaaaag gtcttatttc
     7261 tatttttaaa accaccaaaa actcctataa tcaatccacc taaaaccata cctaaaaatc
     7321 caatcatttc aataatagac aggtatatat aacccttgcc aaatgttcgt tcaataagaa
     7381 gtcctataag aaatcctgat ggaacacaaa gaagcatgaa tgctccataa gtaaaaagca
     7441 cttttctaat gaacttatct gaaaaacagt actttatccc tgataccata tctgcaaaaa
     7501 atgagacttt ttcagtttgt tttggtatat catgtttagg aattttgatg aatatcaata
     7561 atacaatagc aataattgca gtaaatacat caattaaaag aacttgattt attttattac
     7621 caaatccaag tattgcagca gctacaatag gaactataaa ttgtactata gattgtaggc
     7681 tactatttat accattaaaa cgcattaaat gttcttctgg tacaagttga ggaatcattg
     7741 cgtttacagc aggtgtttgt acaccacttc ctagtgaacg tataacagat attactgata
     7801 tggctattaa ttcacttgtt gtgccatttg atgacatcat aaatagaatt agaactaatg
     7861 tagatatagc aattgttgaa tctgatacaa ttatgagtac ctttcgattg tagtagtctg
     7921 cccatacacc agcaaaaaaa gaaattatca tttgaggtat aaaggagcat acagttaaaa
     7981 ctgttaccca tacacctgat gatgtctgaa gtgtgacata ccatatcatt gccatttgta
     8041 caagtgatga gccaaataag gaaatatatt gacttgctaa aaaaagaatg acttttttct
     8101 tccatgtaga attagtattt ttgttttcca tcctattcct cctttgattt gtgtgttgaa
     8161 tttttcttgc tcttaaggat aacacacaaa tcaaagtctg gagttagagt ggagggctag
     8221 gaaaattgtt ttttcataat ttgaagatga gatttcatgg tttttgcatt atgttcagct
     8281 tctttcaatg aagttatcag tttgtcacac actgagataa tttcgtcatc atcttttgga
     8341 gtgtcaagga cagttttaat attagtatta ggattagaag ataaagcatt taacattcgt
     8401 aaaatagctg aaagagaata atttgcacaa cgaagtgcgc ttataatttt aagtcgtttt
     8461 atatcttcat cagtatatac acgataacca ttttgttttc tttttacttt taacaaacca
     8521 ttcatttccc aatttcttaa agtatctatt gtaacattta agtgttctgc agtttctttt
     8581 ctagttaaaa agagtttatt tgtttctgga gtatttccat ttaaaatctg tgcaacaata
     8641 gtaagtgctt cctcggcatt agatttttct atttctaatt gttgcaagta ttgatttaca
     8701 agactaatag ccttatcaaa gtccctattc gctgatgttc ttacaatctc aagggcatct
     8761 tttcttaatc ccctttgtac cacttcaatt ttcaaggctg tacgagcaaa tctaaattgt
     8821 tctatatgaa aatcattaaa gatacgataa ccattggtat tacgcttagg tttaggtatt
     8881 aagtttagtt cttcatataa acgtactgta ttaggatgta caccaattaa atctgctacc
     8941 tctgatgtcg tgtaagtgtc cattagtatt caactccttt tagatatata gtattagtca
     9001 taataacacc aaacaaaagt ctggtgttat aatggagggt ttggctatct aagagtaatt
     9061 agtttatgaa agagtaatta gtttatgaaa gagtaattag tttatgaaag agtaattaat
     9121 ctattataga agtaagtata tatttttcaa taaactccca tctatcacga ggtttaaaca
     9181 ctattttaga tggtatggct attactaagt catattgtgg aatacaacaa atagcatttc
     9241 ctccagttcc cattgctgaa taccacaaaa caccatcttt tttacatagc caccacagat
     9301 aaccgtattc attactattc attttaactg attcttcaat ccacgattta gatataatac
     9361 gtttattatt ccaaatacca tcatttaaat acagaaaacc aaatcgcaac atatctctag
     9421 cactcaatgt aagtccccag ccacctatag aataaccctg tctatctttt gcccaaccct
     9481 taagattttt tccaaagaaa tcttcaaaac caaaatcttt catatcataa tctggtataa
     9541 ctttcatacc aataggttta aataagtatt cattagcaaa ttcacgagca gattttccag
     9601 tagtttttgt tataatagct gaaagtaggt gcgttccagc tgaagaatat ttgaaagtac
     9661 caatttcgcc tttttgacca agttgattca aggtatattt tatccaatct ttttgtttgc
     9721 aaagtctttc taaagactca gtcatatttt taaaagggta tggtgcagtc attgtaagta
     9781 ggtgacgtat agttactgct tttttacata tttcagaagg actacaagta tattcaggaa
     9841 aaaaatcaac aaccttttgg tcaacatctt ttatatatcc tttatctatt gcaataccta
     9901 ttaaggctga tataatactt tttgtaactg atgcaacatg aaaagtatca tcagcattat
     9961 atccattata gtacttttca aagacaattt ttccttttct tgcaataatt ataccattta
    10021 tattgctata ttgtgagatt attaaaggtt caagttgtga aagcttttct gaactcatac
    10081 caacacttga aggatctact ttttcaaaaa ttaagtctaa gcaattgttt ttattcatta
    10141 aagatacctc cctgttatag attttggatt ttcttttaga gcttttggag aaccttctgc
    10201 aattatataa cctcctttgt caccaccttc tggaccaagc tcaacaatcc agtcacaaac
    10261 atttaataca tctatatcat gttcaacaac aattacagaa tttccatttt caaccaattc
    10321 atctaataat tgaatcaact tagaagtatc atatagactt agaccagtag ttggctcatc
    10381 caatacataa aggatattac catttcgttt tttaccaatt tcttttgcaa gtttgattct
    10441 ttgggattca ccaccactta aagttggtgt aggttggcct aattttatat accccatacc
    10501 tatttgttct aatacattta agtgtgaaac aatatttgga atatccttga agaaatatac
    10561 agattcagaa acactcatat ttaaaatatc atgtatattt ttatttttat atttaataga
    10621 taaagattca tcattaaatc tttttccctg acattcactg catatatggt ctatacttag
    10681 attatttccc aaccagacct tttcatatcc actaccacta catttaggac aagcaccttt
    10741 ggagttaaat gagaaatgac cagctgtaaa tcctcgttct aacgattttg gctgacctgc
    10801 aaatagtgta cgtatcttat cccatatacc aatataagaa gcaggagttg agttcatatt
    10861 tttgccaata ggagattggg atatctctga atatccagaa atatgtttag taccaatcag
    10921 tctatctgca atagtttcaa caactgcata atcgtcttcc tcacctattt cactctctga
    10981 agaatttatt tgattattga tagtatggtt attaaattgg cttctaagaa gaggaagtag
    11041 ggtgtctgat ataagtgaac tcttgccact acctgatttt ccagatattc caaccatagc
    11101 actcaaaggt aatgatacag ttacattttt aagattattt gtatttgcat tttgaatagt
    11161 tatacaaggt attttatcag tatgtgtaat atttttattg cttgttctat taggcattgg
    11221 atattttcca gatagatact gcccagtaag tgatttgttg gattgaagta gaccttctaa
    11281 atctccttga tatactaatt gaccaccttc aacaccagct tttggaccaa tatcaataat
    11341 atgttctgcc attttaattg tgtttttatc atgctcaact actatgaccg tattgcctaa
    11401 atctttaagt ttctttattg attttaagat gtctattttt tctgattcat gcaatccagc
    11461 tgttggttca tcaagcacat aaattaatga gtccatctct gaatcgagat gtgaatttaa
    11521 aaatagtctt tgcatttccc caccactcaa agttgacatt tctcggtata aggatagatg
    11581 acctaatcgt gattctatta aatgttgagt tttggataaa atatcattta caagatttgt
    11641 accaaatgtg tttaaattac cttgatttat taagagttta aggaaatcat caatttctaa
    11701 aatcgtcatt tttccaagtt ctccaatatg ttttccgttt aaaagtactc tacgtgcttc
    11761 ttcaccaatt ttaaaaccat tacaatctga acaggcagtc atagtataaa ctccatttaa
    11821 atcttcgccc cttttgtaac gattgtgaaa tacctttgat aaagaggaac tttttttacc
    11881 attttcataa tgaccataga gtacttcatt tcttatttct tcaggtagtt gtaagaattg
    11941 tatgtctaaa taatcgttga attttttaga aaatactctc aaatatcctg gtgtaatctt
    12001 tgctctatct aagacttgtt ttagggtgtc atgcttatca aggactaatt tttcaatatt
    12061 aatctcaaaa tatgcaccat gtccagagca cttcatacac attccatctg aagagttgta
    12121 tgagaaataa cttggtctta atcgttcttc ctcatatcca caattattgc aaattagatt
    12181 atcgcttaca ggagtatcac acatagtaca cattatttga ccttccactg aatacaatag
    12241 tgtaagcatg ttgagaatat tggttcttgt gcctactgtt gaacgaggat tgctctggcg
    12301 aataatattt tgttgaacag ctatagtggg agctaaacct tgaatattat caaacttatc
    12361 ttcactatca atacctgcaa gtatacctaa agattgcaga tattgtttac gcccttcctc
    12421 aaatacaatg tcaaacataa ggctagactt acctgagcca ctgacacctg ttgcaacaac
    12481 aagcttatct ttggggatag aaacatctat atttttaaga ttgtgtatct ttgctccatt
    12541 aatttttatt tctttcattg gttcacctca ttttatcaat tttatcaaac cgtaaaatag
    12601 ggatatatta atccttaata caagaataga ttaggtgagg ttattaaaaa ggttctatag
    12661 gtaaatatat atcgaccaag tgtctatttt gagggtgatt gtgtgggttg ttaagatata
    12721 cttcaaaagg gaaggaggca cgtagcttat aattaccatt tgatagccat tcattataca
    12781 taaaatccca cgcatcacta tattcagatt ttgaaatatc aaaatgtccc acaagatatt
    12841 ttccagaagg tattatcata ttgccaagat tgtcattctc tttgacaact atgttatctg
    12901 gaatagtcat gcaaatacta gtccttaatt gatgctcctg tgtaaattgt ggattatcat
    12961 gataaatggc taatatttgt gtgttttcaa gtccaagtag attctgctca cttgcatatg
    13021 tgaataaccg ttctaaaagt tttgggaaag tactggttag attaccatat gaaccagtat
    13081 acctagtgta aatagtattc atattatcaa gttctagaat ttcaatttca cctttaacct
    13141 ctctagtatt cttacattta ggttttgata tgcttctatt gtactgagaa attttatatg
    13201 gttctttgca attcttgcta taattgtttc tatattttat agggcttatt ttatagtaat
    13261 ttttaaatgc tctcgagaaa actgctgaat cagtaaagcc aaagtagtgt gcaatatcag
    13321 taacagtcat gtcagttcta tgaataagaa aagcagttgc attttctagt tttagcctat
    13381 ttacatactg tgccaaagtt tctttttcta ttgctttgaa gattctatga aaatgaaatt
    13441 ttgaaaaacc tgctatatta gaaagttcat caagagaaag aggttcatgt aaatgttctt
    13501 ctatatagtc ttgcactttg caaatacgat ttagatattc ttttttactt ttagcatttg
    13561 tcatatatag ccctccttat tgtgtaaaat gtgtatcaat taatttatag caatatagta
    13621 ataaaatttt atgtttttgt aatttatgat aaataagata gcgtttaatt ttttataatt
    13681 gataaaagat ataagatgcc ttatatttgt ctttgcatat aagtatagtc ttcgtaataa
    13741 ttagtatacc atagtgattt atttttaatt gtgtatttat ataaatacac aacttatgat
    13801 atggacgaat tattatgcaa ataagctgta attaaataaa ttgcaatata aaccagttga
    13861 aacataagtt agggaaatat tatcaaagtt attatttagc ataagagtat agagggaata
    13921 aaataagatt aaaaaattac atactaaatt taataaaatt tttatattaa aaataatatt
    13981 aagtttattg tttaaataaa aaagttaaat ctacactatt aacttattat acttaaaact
    14041 ttaaaatgaa aatatcaaag aatacttttt aataaaaata atcatttaat aagttattta
    14101 aaaatctaaa aactttacaa caaattatct atttaaattg gaggagtggg aatatgagta
    14161 atagttttta tcaattaaat tcagcagtat tatattttaa tgaaaaaaga gatgtaaata
    14221 gaataaggtt taatcactat gtaatgagaa aagaaaatat acaaagatta aaaggaactc
    14281 tgccaagagg acaatttatg atgacagtaa ggaaagctgc atctgacctt gatgtatcta
    14341 tatctacaat aagtagactt gtaaatgaat ttatagattt aggtatattg aggttaataa
    14401 gtaggggagt aaagggaaat tgttgttctg tatatagtta tgtttgttct gaaagtagta
    14461 atgcagaaat tgtaacaaag aatggtgata ttttcaaaaa tatagagaaa tacattgatg
    14521 caactattaa caataaccaa aaaacaatga aatataaaca tagagatgag ttgtttaaga
    14581 acagtaatac caacatatac agccgtataa atcaagagag tatagacaaa gattatgatt
    14641 tgataattca tactgggtat gaaacagaaa atgagacaaa gaaaaaagaa ttattaaaaa
    14701 ataatttaaa taaaaagaat ttaaataaaa atacctttga aaattcggat gaagatttga
    14761 ctgaagattc tacttataaa aatccagaaa gcatacatga aattattata agaaaattaa
    14821 atagtgaatc aggaaaaaat tttaaagctg atttgagtat aactaaggca cttatagata
    14881 aaagattaaa agaagggtat agtttagaag atttttacaa ggttatagag gcaaaggtaa
    14941 gaagatggag atatacagat atggaaatat atatagaacc aacaattctg tttgggtatg
    15001 aatttgagtc gtatttaaat gaggagagtt ctttatctgc ttgtaattat ggtgatatgt
    15061 gttatgaaga tatgtattga gatatttatt aagatattag ttgcttttta gttgtttaaa
    15121 atatgtttat gtataaatag tgtattaaaa tggagttgtc tcaaaataga gagaagcctc
    15181 ttcttaattg tttaaatgat gaaaatatat ttgatttaat acaaaggaga gtgctttatg
    15241 agttagaaga tttattttga gacactcact ttttttaata tactggagaa atataaccca
    15301 ttttacaaga gtgcataggt atatataatg gcataatgtg gatttaaatt aaaaaaaata
    15361 aaataaagcc ataaatattg aaattttcaa tatttatggc tttattgctt gtaataatta
    15421 atagaatata tattttttat taatcatcta tttcaaattc taatatttta ccagtaattg
    15481 cattaattgt tatctcatat tcagtttttc cttttattat ttcaccttca tattctttgt
    15541 catcttcatc atacttaaat tttactattt tcccaccagg cactttatct agcattattg
    15601 atttagcttt ttcagcacta ataatagaac tgttgtcatt agtattagag ttattcttat
    15661 cattatcatc aaagtcatca tcagaatcat tgtccatgtc aatatctaca attcttccat
    15721 caaatgcact tatctctaat tcatatgttt tcttattttt tattacttta gcctcatatt
    15781 cgttatcttc agcatcatat ttacaataga ttaaattacc attaggaata gcatctaatg
    15841 ctatagactt agctttatcc aatgatatat tttgtgtacc taaattatta tcatttaagt
    15901 catcatcttt ttcaatttct attattttac cagagtaggc atcaatttct atctcatata
    15961 ggatattatc ctttataact ttgcagtcat attcattatc atcttcatca taataacaaa
    16021 ctaaaatatt gcttcctgga agagcttgtt ttaatatttc tttagcctgt attaaagata
    16081 tttttttagt tttatttctt atgttcacat tttttagttt taaaatatct tcaaatgctt
    16141 tttgattata tcctcctcct acttgtgtta tttcatctat atctttattt ttaataaatt
    16201 ctttttgact atttacaagg ctaccattag atatcattat aggagaattt tctttagcag
    16261 ctagtactcc tattgataat gaatctacta atgcattttc ttggttaata ccatctttag
    16321 ctacaaatac attatttatt tttttatctt tataaaattt atcaataatt tttgcattag
    16381 tattgtttct atctgaacca ctgattcttt ctctgtttgg atatttcttt actgtattgt
    16441 ctgataaaat cttatttcct ccaactatgt aagatttttt tatagaccta ttgtttaaga
    16501 aatttatact actatcattg ctgttttcat ctgatactaa tattataggc atattatgta
    16561 ttgctgctgg agaagctata ctaactgcat cagatagtcc ctttagtcca tttacaactg
    16621 caacattttc tacctttttt atcttatcta tttctttaag tacatttgta gacatttcat
    16681 atatattgtt tcctactatt ttatttattt ttatgttaag tgattttatt tcattttcta
    16741 ctttggaaga aatgctattt ccactatcta caatgtacac attatctaca ccaagccttt
    16801 taagctcagc cttagttgaa ttttcaatac tgttgttgtt tactaaaagt ataggtgcat
    16861 tctttagctt agcaaatgga tttgcacaaa gtgcactttg aatagaatta ccattaacta
    16921 taatggctgt ttttgattga acccatccca atttacttac ttctactgct gtttcatatc
    16981 ttgttttacc tattaatctt tcttgctttg tagtattgtc tgcaaaaatt gctgaagaac
    17041 tagaaaaaaa catcatacct gatattaata tagctaaatt tttcttattc atatttttac
    17101 ctcacaatct ttaaaaattt gttatttagc atacttaata aaatataatc ttaaaatcaa
    17161 attgatgctg agtttgaagt tacaaaatca acaaataaga tttctttaat acaaaatttt
    17221 cctttttata tttaacattg tatcacaaat ataaaaagga aaaaactttt taaaaagggt
    17281 atacactatt cattttttat cttataaata agtctttacc actgttttat atattttaaa
    17341 atagacacaa gacctatttc taaatctttt ataaacattt taggtgaaat ttctttttaa
    17401 acatatctaa aaagtatttg tagtaatatt aatggactga atttcttaaa gtatatattt
    17461 ctttacatgt tggagtttgt gaagtttgag aattggaggg tgaaagaaac atgtaatgga
    17521 ttaatattaa agaactgtat ttttataata tttgtcttaa aaataaaaaa atctattgac
    17581 ttgaagttaa ctccaagtag taaagtataa ttatacaaga attatatact tgtaagaata
    17641 gttaaagtag agagaaaaaa caaacaagtt ttaaaggggg aagtaaaaca atggaggcaa
    17701 aaaaattagg atttggatta atgcgtttac caataaaaga tgaaaatgat gttacaacta
    17761 ttgatatgga acatttaaat aaaatggtag acactttttt agaaagggga tttacatatt
    17821 ttgatacagc ctatgtgtat cacatgggaa aaagtgagat agcacttaga gaatctctag
    17881 taaaaagaca caaaagagag agttttacta tagctacaaa acttccatta atggctttaa
    17941 agaaaaaaga agagcaagaa accattttta atgagcaatt agaaaaatgt ggtgtagact
    18001 attttgacta ctatctttta cacaatatag gcgtgtcaca ttatgaagta gctaaaaaat
    18061 ttgatagctt taagtttatt gaagaaaaga aaaaagaagg aaaaataaag aatattggtt
    18121 tttcttttca tgatagtgca gaattattgg ataaagtctt gagtgagcat ccagaagtag
    18181 acttcgtgca attacagatt aattatttag attgggataa tgaaagcata caatctagaa
    18241 aatgctacga ggtggcagag aagcataata agcctgtaat tgttatggag ccagtaaaag
    18301 gaggtacact tgcaaagata ccagaaaaag cagagaaatt attgaatgac tacaatccag
    18361 atatgtcaat ttcatcttgg gcaatacgtt ttgcagcaag taaagataat gttatgatgg
    18421 tcttaagtgg gatgtcaaat atggaacaat tattagacaa tacaggatat atgcaaaatt
    18481 tcaaaccatt cgtacaagag gaatataata ttatagatga agcagtagag attatcaacg
    18541 aatcaatttt agttccttgt actgcctgtc agtattgtgt agaaggctgt ccaaaaaata
    18601 tcgctattcc aaactatttt gcgttgtaca atgcagaaaa acaagctctt aatactggat
    18661 tttcaacaca gatggtctac tataataatt atactaaaac ttatggaaag gcctcagatt
    18721 gtattgaatg taaacaatgt gaagaaagct gtcctcaaca cattaaaatt atagatgctt
    18781 taaagaatgt agcagaaacc tttgagaaat aattcaatct atacaatatc aagaggagaa
    18841 gatatgtatg acgatttcag aagttagtaa aaaatacgag ctttcagcgg atactttacg
    18901 atattatgaa cgaattggtt taataccacc tgtaaataga aataaaagtg gaattaggtc
    18961 ttttacagaa gaagattgtg agtgggttaa tttcataaag tgtatgagag gtgcaggtct
    19021 ttctattgag acattaattg agtatgtagc tatgtttcaa caagggagca gtactatcaa
    19081 agctagaaaa gaacttttaa tagagcagag aaaccaacta gcaaaaagaa tagaagaaat
    19141 gcaaaaaact ttggaacgat taaattttaa gattgataga tatgaagaag gtattattga
    19201 gaaagaaaaa gtattaaaga gcagtagaaa taagaaaatg gaggcagtat cttatgagta
    19261 aaaatgtatt aatagtatca gctagtccta gaaaaggtgg aaattctgat ttattgtgtg
    19321 accagtttat acaaggggta ttagaatcta aaaatcaagt ggagaagata tttttaaaag
    19381 ataaagatat taactattgt actggatgtg gtgcttgtta tgaaaaagaa gcaaattgtt
    19441 cacagacaga tgacatggga gaaattcttg aaaaaatgat tgaggcagat gtgattgttt
    19501 tagcgactcc agtttatttt tatactatga atgcgcaaat gaaaactatg attgatagaa
    19561 cttgctctag atatactgaa atttgtgata aagatttcta ttttatcgtt acagcagcag
    19621 atgaaaatgt ggctgatatg gaaagaacaa tagaaggatt tagaggattt acatcatgtc
    19681 taaatggttc taaggaaaaa ggtatagtat atggtgtagg tgcttggaat gtaggtgata
    19741 ttaagggaag taaggcaatg aaacaggcat atgaaatggg taagttggcg tagtatgttt
    19801 gtataaaatt gtataaaatt gaatatattc ttatcatttc aacaataaaa agaggcttat
    19861 ctgtattttg agacagcctc tttgtgctat atcatttatt tttattctat atccttatta
    19921 taccctttat ttttttatgc ctatttaagt atctgttgtt actcatatat tttaataatt
    19981 acccttaaaa aactatacag attcctgcat aatattattt tctttagtaa ttaatttttc
    20041 taggtttttc caatccattt cttccatatt tgcaaaataa tgaccacttc ctatgcaagt
    20101 caggtaagac tttccatcta attcaaacga agaacctcca atacactttg aattacattt
    20161 cttacaagta cgagttttag ttatactatc tttaatagtt ttagagcatt cctccacagc
    20221 atctttatat gtatttagat gaaaaagatt tgctttaact ctccattttt tttcattaca
    20281 ttcaatagta aataagctac gttttggttt cttagttgaa tatactattt tgtaagaacg
    20341 agcacctgtt tttggttcaa ttttacaatc taatgattta ccaagttcat gtaaatgaca
    20401 tgcaatatca taatctttac cacttagtac ttctaacatt tcttctgttg tttctgctgt
    20461 taattcactt ttgctcatat taaaaaaatc cccctatata aataataatt tcatatgaaa
    20521 ataattaata taagtatatt aaataaaact attaaaatca ataaaattac tgcaatctta
    20581 cattattggg catagaatga gagctaatga tttattagaa ataagactta atagtatgaa
    20641 aatttactta gacgtggtac aattctataa aagatttaaa actaggaaag gagaaagttg
    20701 ttgagatacg gccaatataa caatttattt ataagttgta aatttattat gagattaatt
    20761 agattgttaa gtaatactat caaaaggtag ttttttggat tttcagcaac agtggtagat
    20821 attgataatt ttttggttat tattatattt agctgttata ttttcaatag gctctatgat
    20881 aactagggta aataaggtat gggtaaaggt tttattattt ataatagtgg gattgtcaac
    20941 tatagttctt tcatatgtaa taacttgatt atgcaaaatt ctatgaagca ggaaccctgt
    21001 gactttagtc atgggaggtt cagaatttaa ggttaaaaaa taactttaat ctgtaaattc
    21061 tcaaaacaag aattctcatg ttggtaaatt tctagatatg agaaaaaaat tgacatcata
    21121 aaaaagtaat tttagagcgt tttttgacga aaaaattcag aagtaactat tttgaatgac
    21181 ttcacaaaat tttatatata aataaagttt ggcacgttaa ttgctttaat aaaagttaac
    21241 aagacacaaa taaacataat catctaagta ttgattattt gaagttttag atttgaaatt
    21301 taatctaaag gttcgtatta atattggtgt ttaggaaatt ttattttcct gtaaatataa
    21361 cttaataata ggaggtgaag tcatgtcaaa agtagtaata gctacagaga aagctccagg
    21421 agcaattgga ccatattctc aagcaattca agttggaaac atagtttcta catcaggtca
    21481 acttccaata gatatgaaga ctggcgagtt agtatctgac ccaaaagaag caacaaaagc
    21541 ttctttagat aatgtaaaag caatattaga acaagctggt acaagtatgg ataaaatatt
    21601 taagactaca gtattcgtaa aagatttaaa ggattttaat gatattaatg aagtatatgc
    21661 tacatatttt aaagaaaatc caccagcaag gtcatgcgta caagttgctc aattaccaaa
    21721 agatgcagtt ttagaaattg aagcaatggc agtattataa gtattataac aataaaacca
    21781 ataacaaaac taataaaaat taaaaactaa taaaaaaagt ctacaattaa aaaagtttat
    21841 attaaaaaag tctatataaa aatctatcta aatatttaac tattgagctt ttctcatata
    21901 atgtatattt ttatgtcaaa aatatatttg ttatatgagg aaagcttttt tttattattg
    21961 tattgtgatt tattttattg tctgcatatt ataattaagg ttactatata aaacaaactt
    22021 tttataaatt aatattgtct gttttaacgc aaatatataa ataagtaatg ttttatatat
    22081 attttaaaga gtgactatat gttaaaatat agctaaactg ataatttggt aaattaaatt
    22141 ctaatggggg aaactatgtt aagtaaatta aaagaatttc aacaagaaat gataaaatac
    22201 actgaaacag tagctagtgt gttagatgta gatattgaaa tagttgacga tagattaata
    22261 agaattagtg gtacaggtct gtataaatca aagataaatg aaagcgttgt tacagaagga
    22321 tttatttatg acaatgttat acagacaggt caggaattag tcgtattgga tatatgtgat
    22381 aatcagcttt gtatagaatg ttcccattac atgaaatgct taaataaagt aataatagca
    22441 gttccaataa agtataataa tcgaactata ggagtaattg gtgctattag tacagataaa
    22501 actaaaaaag tagaaataag tgcaaaaata gataattatt taaaatttgt taatcatata
    22561 tgcgatttaa tttctatgaa aatagaagaa catgaagcgt caaaaaatag cagtagaaaa
    22621 atggatatga tgatagaaat cattgaaaat gttgaaaaag gcgttataat actagacata
    22681 aatagcaaaa tatcttatat aaacaatata gctctaaaaa aattagatat agataaaaat
    22741 ataatagaaa atatagtaaa tatagtatct gttgaatctt cctcaaatgg acatgaatta
    22801 ctagaaattg atattgataa caaaatttat aatataaatg ccaaaataat tccggtatat
    22861 ccatatataa atcaatacga caaaataata atatttgaca agacatatat caatcataaa
    22921 ggacatggaa aagtgaatag tggctgggga aatagtgata tagagtctat aattggaaat
    22981 tcagaagcaa tgttaaaagt aaaagagaga actaagaaat tagcaaagtc aaattcaact
    23041 gtacttataa ctggggaaag tggtacgggt aaagagctaa ttgctagggc tatacatgct
    23101 gaaggtagca gatggaacaa gccatttatt gcgataaact gtgctgctat tccagaaaat
    23161 ctccttgaaa gtgagctatt tggctatata aaaggtgcat ttagtggagc tagtagtgga
    23221 gggaaagtag gtaaatttga acttgcaaat gaaggtgtta tatttcttga tgaaatagga
    23281 gatttgtcaa tgcctttaca agcaaagtta cttagagttt tacaagagag aaaatttgcg
    23341 agaattgggt caaataaact tatagattta gatataagag tgattgctgc tacaaataaa
    23401 aacttattga aattagtaaa tgaaggtaag tttagggatg atttatacta tagattgaat
    23461 gtaattccta taaatttgcc acctcttagg gaaagaaagg atgatattga ggcaataatg
    23521 atgaagtttg cttctaaata ttctttagaa ttaggtattc agttaaataa aatagaagaa
    23581 aatgtaatga atatgttgat taactataat tggccgggaa atataaggga actggaaaat
    23641 gcagttgaat atatgatgaa tttggttgga gatgatggaa taatatataa agatatgctt
    23701 ccattagata ttttaaacta ttataatatt aatggaaata tttataaaaa taaggatgta
    23761 aatataatat ttgaagatga tatagttgga gggatagtag agaatcaaga aaggatactt
    23821 tcaattaaag aattagagtt gacttacata aacaagttgt tgaataagta tggaagagat
    23881 acaaagacga agaagaagat agcaaaagac ttaggcatag gtttggctac actatataga
    23941 aaattggaag aggaacagta gtaatataat attaaaatga taggtatttg tgtgttttta
    24001 tagataggta tttttacttt atggtggagg tgttattatg caatatgcga tagagctata
    24061 ttatgataaa aaaacggaaa agcaactttt tgatttatct aaaaaaatcg ctgatgaaaa
    24121 aattagtacg aagtacttag aatggaaaac aagacctcat cttactttgg cttgtttcaa
    24181 tgatgtggat gaggcttgtt gcatagacaa gctaaagggg tttgcacaaa accataaggt
    24241 aatacctgct tacattggtt cagtaggcat gtttaatgat actaaaacgg tgtttgtatc
    24301 acctataatg aatagcagta tgtatcagtt tcagagagaa ttatatgagg tactacaaga
    24361 ttttgattca aatggttggg aatggtacca ccccaatcgt tgggtacccc attgcacaat
    24421 agcacttact ggagatgatg aaagtgaggc tttttttcgg gcaagtgatg tattactgcg
    24481 tgagttcaaa aaaataagtg gtgagtttgt ctcaatagga ttggttaaaa ttacatttcc
    24541 tgtggaagaa atttttacag tgaatatgaa taggtaactt taactctgtt gtggatgtta
    24601 tgaatatttt gtatagtgca tttcatcaga taaatgcgaa gttgcgaatt tcgacagctc
    24661 aatagtcgca agtagggcac aatggtacac atattgcact tttgcttatt ggggggacgc
    24721 ccatgtaaac ttctgtaaga agctatgaaa agatttaagc cattttggag gctttgggta
    24781 ataaagaata taaagtatat aaagtatata aatttataga gtttatgcgt aagaaggtta
    24841 tagccatata tttatagaaa ataaaagtag taatatatct gacaaaacaa tagacatata
    24901 aaaaataaga gcataataaa ggaagaatta agacaaataa acgatttctc gaattgataa
    24961 ttctcgtatt gataaaaatt tcccaatatg agaatttttt cttttataaa tcttattttt
    25021 cacactcaaa atttataaac tttaaagaaa ttttataaaa gtatgtaatt ccaacataaa
    25081 aaaattgttt ttagaataaa taatattggc acggtaattg ctttgctata aggcacaaag
    25141 ataaaaaatt aaaatgacac cgaaaaattt gaaaggggaa tataaaataa atgagagaaa
    25201 taaaatggaa attaaataac ttacctaaat cagaggaaaa agaaaaagga attgaatttt
    25261 taaaagatga agagattgca aaggctaaag cttttcatga gagctttcca caatatgaaa
    25321 agactccttt agttaaatta gataacttag caaaattact aggcgtaagc ggaatatatg
    25381 ttaaagatga atcttataga tttggcttaa acgcatttaa agttttaggt ggttcttact
    25441 ctatgggtag atacttagct caaagattaa atacagatat atctgagtta gggtatgata
    25501 aattaacttc aaaagaaata aaagaaaaat taggagaaat aactttcttt acagctacag
    25561 atggaaatca
//
LOCUS       DAEOTL010000051        25355 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEOTL010000051 DAEOTL010000000
VERSION     DAEOTL010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25355
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.051"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(246..926)
                     /locus_tag="KRH82_002499"
     CDS             complement(246..926)
                     /locus_tag="KRH82_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8655772.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKIRNITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
     gene            complement(2197..3069)
                     /locus_tag="KRH82_002500"
     CDS             complement(2197..3069)
                     /locus_tag="KRH82_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8655773.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(3463..4041)
                     /locus_tag="KRH82_002501"
     CDS             complement(3463..4041)
                     /locus_tag="KRH82_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBG8655774.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(4099..4815)
                     /locus_tag="KRH82_002502"
     CDS             complement(4099..4815)
                     /locus_tag="KRH82_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBG8655775.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            5006..6091
                     /locus_tag="KRH82_002503"
     CDS             5006..6091
                     /locus_tag="KRH82_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBG8655776.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(6246..6905)
                     /locus_tag="KRH82_002504"
     CDS             complement(6246..6905)
                     /locus_tag="KRH82_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8655777.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(7122..8414)
                     /gene="lysA"
                     /locus_tag="KRH82_002505"
     CDS             complement(7122..8414)
                     /gene="lysA"
                     /locus_tag="KRH82_002505"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBG8655778.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(8432..9625)
                     /locus_tag="KRH82_002506"
     CDS             complement(8432..9625)
                     /locus_tag="KRH82_002506"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBG8655779.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(9986..10603)
                     /locus_tag="KRH82_002507"
     CDS             complement(9986..10603)
                     /locus_tag="KRH82_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655780.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(10773..12473)
                     /locus_tag="KRH82_002508"
     CDS             complement(10773..12473)
                     /locus_tag="KRH82_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655781.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(12870..13433)
                     /locus_tag="KRH82_002509"
     CDS             complement(12870..13433)
                     /locus_tag="KRH82_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655782.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(13592..14305)
                     /locus_tag="KRH82_002510"
     CDS             complement(13592..14305)
                     /locus_tag="KRH82_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBG8655783.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            14597..16261
                     /locus_tag="KRH82_002511"
     CDS             14597..16261
                     /locus_tag="KRH82_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBG8655784.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(16368..17267)
                     /locus_tag="KRH82_002512"
     CDS             complement(16368..17267)
                     /locus_tag="KRH82_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBG8655785.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(17294..17932)
                     /locus_tag="KRH82_002513"
     CDS             complement(17294..17932)
                     /locus_tag="KRH82_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBG8655786.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(18269..19267)
                     /locus_tag="KRH82_002514"
     CDS             complement(18269..19267)
                     /locus_tag="KRH82_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBG8655787.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(19365..19940)
                     /locus_tag="KRH82_002515"
     CDS             complement(19365..19940)
                     /locus_tag="KRH82_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655788.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            20256..20519
                     /locus_tag="KRH82_002516"
     CDS             20256..20519
                     /locus_tag="KRH82_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655789.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(20956..21333)
                     /locus_tag="KRH82_002517"
     CDS             complement(20956..21333)
                     /locus_tag="KRH82_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8655790.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            21674..22786
                     /locus_tag="KRH82_002518"
     CDS             21674..22786
                     /locus_tag="KRH82_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBG8655791.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(22994..23470)
                     /locus_tag="KRH82_002519"
     CDS             complement(22994..23470)
                     /locus_tag="KRH82_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655792.1"
                     /translation="MVKKRLVAVVISLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(23669..25294)
                     /locus_tag="KRH82_002520"
     CDS             complement(23669..25294)
                     /locus_tag="KRH82_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8655793.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
BASE COUNT         8481 a         4077 c         2602 g        10195 t
ORIGIN      
        1 atataaaaat agctactatc tttttattaa ttaatattca tttgttttat tattacgact
       61 tatattatag ttttatatat tttactgatg tctataatat ttcagacatt ttttatattt
      121 attctactgc tataatttaa ttaagtaaat taaatctaat tttacaaata tatcgttaga
      181 acaaaaactc ttgtaatata ctaacatatt atctatgcct tatcattcat tctgtttata
      241 aagctttata tcttgttaaa gtaataccct acttctctta tcgttataat tttttgagga
      301 tttttataat ctttctctat tttctttctt aatccactca cagcaaccac tacactataa
      361 ttatcatcta aatactcatt catccataca tgttcatata tctccttaat agttagagtc
      421 ttttcagcat tctctataaa gtaatttaat aatctatttt ctgttggagt taactttatc
      481 attttatttt ctaactttat tactccacta gctctattat aatcttctag ttttatatta
      541 tttttattat tatttaaaaa taaatctctt cttcttaaaa tagctttcac tttcgcatat
      601 aatatttcta aatttaaagg ctttattaaa taatcatctc ctccagaatt taaagcattt
      661 aaaatacttt gattttcatt tatataagtt atatgaataa ttgggcaagt agttatattt
      721 ctaatttttt tacaaaaatc ccaaccatca ccatcaacta aaattatctc taaaaatatt
      781 aagtcaaatt tcttgctaaa tatttttata atagcatctt tacaattata tgctaaatag
      841 acatttatcc cctttccttc taaaaaattt ttcagctctt gagaactatt cttatctcca
      901 tcaattatca atacatcaat ttgcattaca atctctccta aatatcatta tttttctata
      961 aagaattgga aaaatatttt tagtacattt tctaatagca ttttttaccc ttataagaaa
     1021 ttttaaatac tataaatcca ttttctttat tatttatata tatttattat ctaaactgca
     1081 cacttcaaaa ttcacatagc atccttgtat ctctagtaag ttattttaag atatacactt
     1141 tatttggtat ttcatttgat tttttattta ctgtataaag ataagcatat acaattatat
     1201 aattcaaagc tatatttttt attctcataa ttatatcttt aacaatttaa tatagatata
     1261 aattaaaatt tctattataa aaataaattt gataatatcc acattattgt ctacgagcat
     1321 taggttatac attaggcact atatataaaa ttattttaac caaagtataa aatttcgatt
     1381 attacacaat atatcacttt tatttttata atattattgt aatttaagct ttagagatta
     1441 aatattctta aataattctt taatattata ttaaaaatta aaaatcatta ttaaatgcta
     1501 ataaaaattt cctattttgg ggaaagggag cttaaaacaa ttttatatta taaatttatg
     1561 ttttttttaa aatgcctcta ttggtatgtt taagtattga tttatataat ttatatagtt
     1621 ataatataag atatattgta ttattttggt aaatacatta ttacaaaagc tttatattct
     1681 atgtcttaat atttataaaa actttatttt atttttataa agtattatat ttctaaaaaa
     1741 gtttcccttt ccccaaaaat ggctacttaa aaaatcaaga tttcatacct aactactaat
     1801 tctatgattt ttaaattttt caacttcttt gtcaaagtta aaataaaata ctaaaagaca
     1861 catattatag tgaacaaaaa agatagaaat acatatttta atataatttt aataagatat
     1921 tatatactta aatacaaata aaattaattt tataattgtt aattaaggaa atgatattgt
     1981 ttagagaaat aaaaaaagca ctctccatga atggaaatgc tttctttaat aaattagttg
     2041 acgtagtaaa gatgtattca gaatacatct ttatgttttg agtctcgaaa tatttatttg
     2101 tattatttaa acgaaaattt attttttaag tgataatcga gtatttacta ataaggctat
     2161 gattctcaat ttcatagcct tattaatata caaactttac tcatacacag aatatctttt
     2221 ccaaatttgc tctaaatcat caaaatgctg tttaatatct tctttttcct tcatcccaac
     2281 agatatagca agggcatttg aaatactaag agctggaact agagaatcta caaatgaagc
     2341 catattactc ttaactagaa gagtgttatc tgcaagtgat gctactggcg caaataagct
     2401 atctgttaat gatattacat gggctccttt ttccttagca taattgacaa tttgataaga
     2461 tttcttagaa taacgaggga aactaatagc aactattaca tcttcttcat ttattcttac
     2521 aatctgctca aaagcatctc ccatatccat tctaattata tgaacattgt caagtattat
     2581 atctaagtaa aaacctaaat attgagctac tacaaaagaa ctcctcattc caagtatata
     2641 tatttttctc gctcttaaaa gtttgttaga agcttcttta aacgctctct cgtcaatttc
     2701 ttctagtgta gaccttatat tatctatatc actttttaaa actttgttta gtattgcaaa
     2761 atcatcggaa taatcatgtg ccatttcaac tctttgtact gtagttagtt tattttttat
     2821 gagttcttga agtgcagctt gtaatttagg atatccacta taacctaatg catttgcaaa
     2881 tcttacaact gtagactcac ttactcctac agtttcaccc aatttacatg cagtcataaa
     2941 tgcaacttta tcataattat ttaaaatgta ttgtgctata agtttttgac ccttactcaa
     3001 tctcgtatat tgagattgta tatttgatat caaatgttta ctgtccttca tttcatttgt
     3061 ttcttccatt tttttctcct tttagttata taaactattt tgttttatta acactgtctt
     3121 tttctctaaa aattttattt tttatctcaa tttcatctta gtttttatca tagcttctta
     3181 aactcataaa attctaactt ttctgtacct tatacttcac atagtatttt cgattaaatt
     3241 tattatacca tctttccttg cattttttaa tatttatcca atatttcttt taaatttttc
     3301 aatttttact catttaaaag ttatctatct tattttgcat atttagatgt atattttgtt
     3361 ttgagaataa gctgttgtat acttattatt taaagtattt ttaataggtc acactatata
     3421 tattaactct taatacaatc ttgtcaagtt ttttagtatt tattatgctt ttttcttttc
     3481 aattaaaatc aattgtggtg ggttattgac ttgatttaaa aacttagatt ctaaaacatt
     3541 aaattcatct tgatttaaat tattgacaag gttatatatg caatcttttt cttcttgacc
     3601 tccatcatgc cctgtatata tggcaatgct tattactcca ttttctttta gcatttctaa
     3661 acttaacttt atagccttta aagttgtatc tggtttggtt ataattgaat gtttcgctct
     3721 tggaagataa cccaaattaa ataaaacaca tgaaacttct tcttttatat attgattcat
     3781 tttttcatgc ccatcaaata tcaattttac tctatctgta tatccttctt tctctagttt
     3841 ctttcttgta gactttattg cttcttcttg tatatcaaaa gcatatacaa agcccttttc
     3901 tccaaccttc tcagctagat accttgtatc atacccattt cccatagtag catcaattac
     3961 tatgtcacct tcatttataa tattttctaa ataaaattta tttatatctg taattttagt
     4021 taaatacttt gcatatgcca taatactatt tctccctact attaacttta tttcattttt
     4081 tctcaattta tttttatctt attttattga ttttaaatat tttatttcat cttctgttag
     4141 gtatctatat tctccaactt tggtgtcttt taatactatt ttccccacag aaatccttct
     4201 taaatttaaa actggatgat ttatagcttt gcacattttt cttacttgtc tatttctacc
     4261 ctcatgtata gttatttcac acactgaata atttttttct ttattttctt tagttaccct
     4321 tattttggca ggtgccgttg tgtaatcttc tatttttagt cctgtttcga attgtcttat
     4381 ctcatcatca cttataattc ccttcacact tgccacatac gttttatcaa tttcatgttt
     4441 tggatgggta agcttatatg ttaaatcgcc atcattagta agtattaata aaccactagt
     4501 ttcataatct aatctcccta ttggatatac tctttccctt acatctttaa gtatgtctat
     4561 tacactgggt ctattgaatt ggtcttttac tgtagttata tatccctctg gtttatttaa
     4621 tactatatat atataatttt cacttggttt tactttttta ttatcaaatt ctactatgtc
     4681 tttttcttca tcaatattaa aagataactc ttttactaca cttccattta cctttattct
     4741 tcctccaaga attatttctt ctgcttttct tcttgatgct attccacaag aagctatata
     4801 cttattaatt ctcatactta atccttcctt atcttaaatt atgtgtgttt aatattttta
     4861 tcaatgttaa ttttgctaca ttattatact atactagacc ttaattaaaa acaagcaaaa
     4921 aaattattta attttcctaa ataattgtaa tttcttttca catactatta atatgtaata
     4981 gctgactaaa cactatttta aggaagtgat tattatttca aaggaaaata taaaatatta
     5041 tttaatagtc gtgtttattg gaattttatt ttttaaattt attaatactc catcagactt
     5101 tatatctagt attgaaggat tcttaaagtt ttttagccca tttttattag ctattttact
     5161 tgctttactt ttaaatccac ttgtgatgct ttttgaggta aaattcaaag cacatagact
     5221 tttagccatt tttttatctt atatatttat aggttttatt ttagcctttg ccattaggtt
     5281 attaattcca tcaatagcta atacattaaa tagattaata aatgaaatgc ctatgtatac
     5341 tgattatata gatagtttta tagaaaaaaa tatgtcaaac atagattttc taaaaacttt
     5401 aattcctcat atacaacata gtttggataa tttattaaaa gaagcaagta attttgttgg
     5461 taaaattcct aaaaacttct taatctatac acttagtata tcttctatgc tatttaatat
     5521 gacaatggga tttatactat ccatatacat tatatatgac aaagaaaaaa ttgcattggg
     5581 atttaagaga tttctatatt cttctactgc tagaaacaag gcagataaca ttatagaatt
     5641 ttttaggact actcatgata ttttctatga ttatttactt ggtagaatat tagactctct
     5701 tattattggt ataattgcat ttttaggatt tcaatttgtt atcagaatag aaaatgcttt
     5761 atttttagct tcaataatat tcttaggtaa tataattccc tattttggtc cttttattgg
     5821 tgcaatccct ccaatagcca tgactatatt atatagtcca caaaaaacta tatgggtcat
     5881 tgcatttcta tttatattgc aacaattaga tggaaatttt atagaaccaa aagttatggg
     5941 taatcaagtt ggtataggag ctatatgggt aatatctgct attttggtgg gacaatctct
     6001 atttggtttc ataggagttt ttctttcagt accaatagct gctgttgtaa aaacttatgt
     6061 tgataaatat atagataatc gtttacaata gattatctct actgtgactt taatttttag
     6121 tttaaaattt aactgctatt tattaaatta tttctcaaaa aatatctctt agtaagaaaa
     6181 aattgctaag agatattttt tataatatat aatttgttca ttaaatttat gcatatattt
     6241 tatacttatt gattatttga gttttgagaa tttccaccac tatctgaacc accagtagta
     6301 tcttgtggag ttggtgctgg tgttggatta ctattatttg gcttttcttg attttgagaa
     6361 gaactgttat tattgtcaga cttattacta tctgattttt tatcattgtt tttagaacta
     6421 gatttattat ttttactact tccactataa gaagatttcc ttgcatctga ttcaactcta
     6481 tacctatctt ctccagccgt atcttttgcc tttttctttc tttgttcctc tgcttcgttt
     6541 tgttcttttt ctaatttagt taactcttct ttctttttag ttgcctcttc tttaataaca
     6601 gaggaaccat ttttgatttt ctctataagt ttaagttcct tgattgcacc ctcataattt
     6661 tttaattctt caaactccgt catatttgac attctcatag cttgcatata catagctctt
     6721 gcattctcat tagtactatc ttcttccagt gcagaggata atgattccat agctttttta
     6781 tagttatgtt tttctaaata tgtttttcct tgctctacta aatttatttc atctttttta
     6841 ttaaatgaac atcctacaag aaatatagat aatatcgata ttaataaaat tactcttcct
     6901 ctcattaaat ccctccttgt catatacttt aaattttatc ataattataa agtttttaaa
     6961 atattttata tttattacaa gaaatttgtt agtaaaacaa aaaataagca gatatgctac
     7021 gaacgataca ataaaccaaa aattaattta gagatacata tcctagcaaa tctgctcata
     7081 ataaacttta atatttaatt tttattatat acttctccat tttatatctc taaagctaat
     7141 aagtcctcat agctttgtct cttacaaatt atcttatcat ttccatcaaa tactgatact
     7201 actgctgctc ttggtatttt attataattt gaagacattg aatatccata tgcaccagtt
     7261 gatgttgtta taagtatatc tccactttta atatccatta tgtttatatc tccaattaat
     7321 atatctccac tctcacaaca ttttccagct attgttacat gattcatagc ctcatgatta
     7381 attttattca caatactaca ctcataacta gcttggtaca acgaaggtct tacattatct
     7441 gtcatacctc catctacact tacataaacc ctaacatctt ttatatcttt tatagaacct
     7501 actgtataca atgtacttcc tgcatttgca actattgatc ttcctggttc tattaccaat
     7561 gtaggtactt ctattccaag ctctttacat gaagtttctg ctttagtgat tatagtttca
     7621 caaaactctt ttatagtttt aggtttatct ccttcgctat aataaacgcc aactcctcca
     7681 cctaggtcaa tttctgttag ttgtatgttg aatttttctt ttatttcttt taccaagttc
     7741 atcattatat ccactgtatc tatgtatggt tctacatcaa atatttgtga acctatatga
     7801 gcgtgaagac ccacaagttt aatattttta tattcactta atttttctat tgctctaaat
     7861 aaatctccat ttactaaagc aaatccaaat ttagaatcta tctgtccagt ttttatataa
     7921 tcatgtgtat gagcttctat accaggagtt attctaaagt atatctcttg agttttacct
     7981 ttatcttcac ataatgcttc aagcaaatct aattcataaa aattatccac cacaaattta
     8041 cctacaccta aatctaatcc catgtttatt tcttctttag tcttattgtt tccatgaaag
     8101 aaaacttttt ccataggaaa atttgattta taagctgtat ataactcgcc tcctgaaact
     8161 acatctaaac acatttgttc ttcatttata agattacaca tgtaaagagg taaaaaagct
     8221 ttccctgcat aagcaacctt attttttccc tctctagcct taaaatattc tatatattct
     8281 ctacaatttt gtctaactaa agcttcatca aatacataaa gtggagtttg atatttttta
     8341 ctaagttcta aacaactcac tcctccaata tataattcat cattatttac agtcatagtt
     8401 ccatgaagtt tcataatagc ctccccaaat tttatatatt aaatacttct gctatttttt
     8461 ctatagctac ttgcttatca tcagaattta tagcacaagt tatacgaatc tctgatgtag
     8521 ttataagttt tatcattata ccattttcat tgaatatctt aaatacttta gcagcaactc
     8581 cagaagtatt tttcatacca agacctacta aagaaaattt agtgatatta ttatcaatca
     8641 ctacatgttc ttcatctgta tatttagata ctatcttttt acattctccc aactcttctt
     8701 ttggaactgt aaatgataca cttatcttat ctaaaatagg tgcagtttgg cttatcatat
     8761 ctacacttat acctatagtt gctatatctt caaataagct agatatattt tcagctttaa
     8821 aatcttttat tgttatagaa ctgtcatcat cactagtagc taatcctgtt attactttat
     8881 cctctaattt catgtctttt ccccctctta tatatgttcc tttttctgta ccacatgtac
     8941 gtccgacata gatttcaaca ccatattttt gtgcaagctc tatacttctt gaatgcatta
     9001 cttgtgctcc taaactcgct aactcaagca tttcttcata ttcaatctca tcaagtttac
     9061 tagcctttga atattttctt gggtctgtaa aataaattcc atcaacatct gtatatatct
     9121 cacattttcc atttaattta accgcaagag ctacagcaga tgtatctgaa ccacctcttc
     9181 caagagtggt tacatcacca tcttcgttga ttccctgaaa tccagttact atcacgacat
     9241 ttccttcatc taaactattt ttaattctgt ttacgtttat atcatcaatt tgagactttc
     9301 catgaagacc actcgttttt atatttaact gataagcatt ataacttata gctttacatc
     9361 caagtgcatt taatgctatt gataataaag atgctgaaat catttcacca gtagacatta
     9421 aagcatctaa ttccctctta ctaggttcat tactcaattc ctttgctaaa gttatatatt
     9481 catcagtgga ttttcccatg gcagacacaa ctattaccat ttgtggattt tcttttcttc
     9541 gttctattat attttctgct attgatttta ttttttcagt atctgctact gaacttccac
     9601 catatttttg aacaattata ctcatgcttt ctccccctca agctaaattt tgataaataa
     9661 aaacgcccaa aggtatactt tggacgtgta aatttcatag accaagtaac cttgtagctc
     9721 accactttaa aagtgacagc cttatgcata ttctgcataa gtccagaaaa tttgtccgtc
     9781 aacaaaattt cttcggctat ataccctttc atcaattatc aacgcttacc agctcctatt
     9841 gaatactatt gaatacagct acctctaccc taggctcatt atttttaatt aatttattaa
     9901 tatagtttta tcatattcta tataatattg caacaattat tttacaaaat gtggcaaatc
     9961 gatagttttc ttttctaaag ttagcttata tacaattaaa tagtttattt aatcctaaat
    10021 ctataaaatt tatgctatac tcattatcat atctctctaa atcatttaat tcggatagat
    10081 tatctggtgt aactaccaaa acgtttggta ctttaaaaaa tggaattgta gatttatcta
    10141 tttttttaga aagattttcg tatttagaaa tgtctatttc attatttaag tcaacatcaa
    10201 ctaaaacttg ctttatatta ccaaattggt ctgtatattc aataaataaa tcgtatttca
    10261 catcatctac actaacattt cggtaaaatc tttttacatc acaacctgca gtattgattc
    10321 taacaactaa ttctgatcct actagagcct ttattaaatc atctccctta aaaagtttac
    10381 taccgtttaa atagtataca taagagaggt ctttataatt ataataatcc acatcacaag
    10441 gatatttttt tagtgtatat tcactacaca tttttctcaa agttttttta aaattttttt
    10501 tattgtatct tttttggtct ccataaattt ttctaaattg agactctgta acacatctaa
    10561 ccctgctaat taaaagtaat atctcttttt ccatattcgt catagtacat tctccttgaa
    10621 gtattatttg caaagttgta ctaatattat attaatttta tgacattaaa tttacaaaga
    10681 attaaaataa aatagctaat ttttatagaa ttaaattcta taaaaattag ctatcactat
    10741 gttaaatact attatcaatc tttttattta aattatacat taccttgatt ttcagaatct
    10801 ttggaatctg tattttcatc agttcctgtt ttttcttttg cttttttatc ttcaaagttt
    10861 gcaatattta ggttatcaaa ttctgacatt tctattacac cagattcttc ttttgaatac
    10921 gatattttga ctttatcacc aacctgagtc aatggcaatt cgctagatac ttttgaagta
    10981 gccctaaata ttatatcttt atttgaatct aaagttacat aataattagt gttaccacct
    11041 cgcacatctg ggcttattct tgtcactgtg ccttctaata cctcatcttt taaatcatta
    11101 tcaagtttta aatcattacc cttagattct aatgcatcct tatagtttct taatgcttca
    11161 ttcttatctt cacctattcc aagtacatta taatcttcaa cagatacaaa tgcaactctc
    11221 ttaacaagac cagccttatc ttttaatgat gatacatatg ttggctgacc caatatatta
    11281 tacattacag ggaacgtcgc ttcataattt ttttcttgaa cattaccttc agctgatttc
    11341 attgcagccg tttcagtagc tcctggttgt ttatataatc tagcttcttt tgttctagaa
    11401 tcaactaaca taaatccaat tgtagattca tctccacctg aagatgttat acctgtatac
    11461 caataagacc tgttatcatt gccataaact aatgatgtac cttctgttgg tactaaaact
    11521 cccttttctg atataacaga gtttaaaaat ccattaacat aaacacccca gtctttaatc
    11581 tggtctgtta caaagctttg tggttgtatt ctatccaccc atttaggtgt gtttttaaca
    11641 tcataaacat ttatttttcc agtttctgca tcaacagtgg ctattcctgt tgcatttgct
    11701 cctccatagc caattttatg ttcatataaa cttacaaccc aataaggtct tccttcatca
    11761 tttatttcaa gagtgaaatc tgtcatacca acatttacaa taccatgtat gtataaatgt
    11821 ctttgtaaat cctgatgtaa gtaggcttct ggttggtaaa ctatctttat tggctttcca
    11881 tctatttctt gaactaattg gacgtcttga ggattactag ctgatacttt tacataacca
    11941 cttgtaccac ttagagatgt tatccattta attatgtctc tgtgaacaag aggcgctacc
    12001 cagtacaact ctccatctac attttgtata tgaaattttc ctaatttgga tacactccct
    12061 attgcaggaa cttctccaag ctttttgtca cctaatttca ttgccatatc ttcatctaca
    12121 agacgaatgt catttacact gacagggcta atgtcatcag taaatttact ttcagttact
    12181 tttcccaata gttctctata tgattttgca tgaagtacag gtgtagaagt tataaaggga
    12241 actactacaa tatacacaag caaagctatt gctattgaaa aattatattt agccatttta
    12301 gatgctcttt catttctatc taacatcata tctagtattc ctgctacaac aaagaaaatt
    12361 attcctactg aaaataaaga tgtaaaatct aatcttagta caggtaattt aataaatgca
    12421 taaattatta ctattattaa tgcaactcca tatgttttaa gatatcgttt catttaatac
    12481 tcctctctaa aaaatgttat tattactatt atatccatat atttacaaaa aataaatatt
    12541 tatcatattt attatatatt aagatatctt tatatattta tagttctgct tattcaacta
    12601 tatttaacat tatacgtgta tgtataaata ctttttatat actgtttgtg ctatccatcc
    12661 cgcacctaaa ggagtgggat ttttgcacta ttctgtatta tatatatcca aaaatattat
    12721 aaaaatacaa atattagcag aaatttaaaa actgaagaaa gtattctaac taagatttac
    12781 aaattcttaa tcctatcgaa gttaaactac tatcttcagc ctaattatct agcaatattt
    12841 ttttatatga aaaactccaa atcaagtttt taaatgtttg cgatttttga tacataagaa
    12901 tgttgtctag aattatattc tgataataaa ccttcatact ctaaggttaa gccagataaa
    12961 ttataaaaat catttggcgt tacttcaaat gcttgtttat ttaaaatgtc tatctcactt
    13021 ttttctaaca tgtcagcaac aaaatttgaa catacatatt tatattcaga ttgtctctga
    13081 atattcatta gtaaatatat taatgccatt gtatcgtaat agtaatcttc tctataatca
    13141 ctaattaatt ttatattttt atatagattt tcatattgta aattatctac ttctaacgaa
    13201 tataccctac acacagtgtt ttttcttata gcatataatc cttgatttat attttcttca
    13261 acaaatcctc caataaatgg attccttgga tttagccttc caaaagaata cattggtttt
    13321 agattttcat ttaatgatat tgacacatgt gtatacagct ttttacttat attccttatt
    13381 aagtaagata atatagttcc tgtatatgtt gttacaatat agactttatt catcatttcc
    13441 ccccaatcta gtaactaaat aatattatac acttacaatt taatatcata agatattcta
    13501 acataataaa tgtggtttta caaattttga ttttaaggta ctttaatatt atataatata
    13561 ataaaaatat aaatataagt tttctatatt tttaaccaac agatgttttc ttcaaattaa
    13621 tcagatgatt tagtatatct tgaacctttc cagagtcctt taaatatcct aatgccccat
    13681 ttatttgtga ttttaaatct atttctactt ccatatccaa atcaacattt ccttttttta
    13741 tagatatatt tttaagtgtt attggataaa gataactttt ttccaaagta atcttatttc
    13801 cattaacctc aaatggaact tttttattgt agttacttaa tattttttct agcattttat
    13861 cacttagttt aaattttcca attttcacat tctcaagact tacaactaag tttccatcct
    13921 ttaaagtagg tctcaattca agttcatatt gactatttac caaaccaaat accttatatg
    13981 gtcctgctac ctttatttta ccatttttca tttcaacaaa attattttca agttcattaa
    14041 ttccatgctt ctgcatcaat gtatatatta aatttttaaa ctcttcctct gaaacagata
    14101 tttttccaac cattctaagt ggatttttta ctacctccat agaatttata tatgagcctt
    14161 ttgataaata ttcttcatct atgattttat tattttgtga actaacatca tatctttctt
    14221 ttggtgtcaa gatatataca acaattcctg caagtactaa aacaataaca attaaactta
    14281 acaaaatctt tgcaaccttt cccataatcg tctcctttac aaatctgtca tcagatttaa
    14341 aataaattta gataactaac ttcacataat attcttaaca atatacatac tataatacag
    14401 tcttttaaaa attaattcaa ccaatctaat gttttgtaaa taaactgtaa aaacatgttt
    14461 ttagtataaa agttaatatt ttgcataata ctcttaatta cacctttatt tttttctaat
    14521 cttggattaa aattaatatt atgcaataca gtgtagtgtt ctgtattata atcaaattaa
    14581 ataggaggta tagaatatgt caaatgaaac gaactcatct aactttataa agaatattat
    14641 tataaacgac ttagaaacag gaaaacatga cagtatcata actcgttttc cacctgagcc
    14701 aaacggatat ttacatattg gtcatgcaaa aagtatatgt cttaattttg gattagctaa
    14761 ggagtttaat ggaaaagcta atttaagatt tgatgataca aacccattaa aagaggatgt
    14821 tgaatatgta gagtccataa aagaagatgt aaagtggtta ggatttgatt ggaacgagtt
    14881 aaattttgca tctaactact ttgatgaaat gtataagaga gctttaatac taataaaaaa
    14941 gggtaaagct tatgtatgtg atttgacaca agaggaaatg agagaatatc gtggtactct
    15001 aactgaacca ggaaaagaaa gtcctcatag aaacagaact attgaagaaa accttgattt
    15061 atttgaaaga atgaaaaatg gtgaatttaa agatggtgaa aaaacattaa gagccaaaat
    15121 agatatgtct tctccaaata taaaccttag agacccaatt atatatagaa tatctcattc
    15181 aacacaccat aatacaggag ataaatggtg catatatcct atgtatgctt ttgctcatcc
    15241 aattgaagat gcaattgaag gaataactca ctctatatgt actttagagt ttgaagacca
    15301 aagacctctt tatgattggt ttgttaaaga atgtgagatg gaaaatatac ctagacaaat
    15361 agaatttgct agacttaata taaataatac tgtcatgagt aaaaggaaat taaaacaact
    15421 tgtagatgag ggtattgttg atggttggga tgaccctcgt gttcctacaa tatccggaat
    15481 cagacgtaag ggatatactg cagaagcatt gcgcaatttc tgtagtgaaa taggggtatc
    15541 aaaagttaac tctacggtag atagtcaaat gcttgattat ttcctaagag aaaacttaca
    15601 accaaaggct cctcttacta tgggagtttt aagaccttta aaacttatta taactaatta
    15661 cccagaagat aagattgaga tgcttgaaat agagaataat gctaaagatg aatctcaagg
    15721 aaagagatta gttcctttct ctagagaatt gtatatagaa caagatgatt ttatggaaga
    15781 acctgttaag aaatatttta gatttttccc aggaaatgaa gtccgtttaa aaggtgctta
    15841 ttttgtaaaa tgtactgatg taattaagga tgaaaatgga aatgtagttg aaatacatgg
    15901 tacttatgac cctgaaacta agagtggctc tggctttaca ggacgtaagg taaaatctac
    15961 aatacattgg gttgatgcta aatcagctat accatgtgaa tttagattat ttgaaccatt
    16021 aattcttgat gatatacctg aaaatgaagg taaacatttc ttagaacaaa taaatcctaa
    16081 ttcattggaa atattacaag gttttgttga acctacacag ataaaagatg ctaaaccttt
    16141 tgataaattc cagtttgtta gaaatggatt ctttagtata gataataaat atacaactga
    16201 tgaaaaattt gtatttaata gaatagttcc tctaaaaagt tcttttaaac caggtaaata
    16261 gtcttacaat caaaaaatga agacttaaaa tataaattac ttctactata aataaactta
    16321 gttagaagta attttttatt tgagtcttca tcatttactt taaatgatta acttttttca
    16381 ctacagattc ccatgacttc tattccatct tttatgcatt ctatgttaag aggaaaatct
    16441 ggtccttttt ctccgtcaat atctgttata agtgaatctt cacattctat atgcaccttt
    16501 ttagttttaa agtatagtat ttcatttcca ttatattgat ctaaataatc acctctaagc
    16561 acacttatca aaactggtat tgattttggt attggcattc ctttaaaaat aattacatcc
    16621 aaatatccat catctatttc agccttatat gctagattta tatttcctgc tgttttgcca
    16681 ttaaaaatca acataagata catatctcca tcataataca tttcctcaga agatactttt
    16741 atcttaaatt tcctcatata caatgcttct tctattccct ttatataata agaaattctt
    16801 ccaaatgaat tttttaagtc tgtgtttatc ctttgtgata catccgtaaa cataccagca
    16861 cttgcaacat ttataaagta cttattattg actttcccta tgtctatttt ctttggtttt
    16921 gaatttatga tttcatttat agcttctttt atatcaaatg aaatttgaag agcatttgaa
    16981 aaatcatttg cagttcctgt aggcaaaatt ccaattggaa tttttatgtc taattctttc
    17041 attgcattta ctactaaatc tacagtacca tcaccaccag ctatcaatat gtgttcataa
    17101 gaactatcaa cttccttaaa tgcattcttt acaggttctt taatagttaa tctatagggt
    17161 atcaataaat aatttttttc ttgatataat tctatgatag tgtctaaatt tgataatatc
    17221 tttttttcac ctgaattagg attgtatata agttttactt ttttcattat ttctccttac
    17281 tcattttatt cttttagtat ccaaaatctt catttaaaaa aatcacatgt attctttctg
    17341 gtgttaattg tctttttata agtgtataac tacagcatat tcttcctgga cttgaacagt
    17401 ctatacatat accagtagtc ttacatccag tatttgtact taatctttta caattggctg
    17461 gagcagctat tgtttttgtt ctttttatag cttcatctac atctttaact attttattta
    17521 ctcctgctat aactattact ttatcaggtc catatatcat agcagcaacc ctattcccat
    17581 tcccatctaa attgtaaagt tctccatcct ctgttatcgc attagtactt gtaaaataag
    17641 catctgcaga aaatgacttt ctatatattt ctttcatttc ttctggtttg atatcttttg
    17701 catatctatc aagaaaatta tatttttctc ttataaaatc aatcactcct gtttcaaata
    17761 aggtcataga acctccacat cctactagag aacctgcttt aactatttct tcaatttttt
    17821 taagaagctc ttctttgtta cttactaaat accctttcat attattgttt tccaaagatt
    17881 ttattgtttt ttctattctt ttttcattaa gccaatttaa attttgatcc attttaactt
    17941 cccccttatt tttaatatgt acttaattat ttataaactt tattttcttt ataagtttat
    18001 tttagtacat ctaaaaaaaa atacaatata aaacttaaat agttttacat aattttttcc
    18061 aaaataactt actcaatcaa aaaaggaaag tagatgtact attctacttt ccctatattg
    18121 tatgtagtat ttattgccta aaatctatat attaattata tgtttcatat tatataatat
    18181 cacagttaat taaaatgtaa tactatcttc tttttaaaca tataaattgt attattaaat
    18241 ttaatatatc caacttcaat aaatcttatt aatttgatga agaagatgct atagctgcac
    18301 ttgttgctgc cattacacat gcaatttgaa tagcaacaac aatatttaaa aatatattat
    18361 tagttataga gcctatatta ttctcatttc gtatcaaatc tgcataaatt gaagctacaa
    18421 tagcagaact aatcattact ctattacttt ttcctaaaga ccaatttcca aagccttttt
    18481 cttctttaag tttatttgaa acatttttta tctcttctat tatttcatct tctctataat
    18541 ctaataatga aattgctcct attattggat atccataata attcatttta caatcatttt
    18601 ctttaaatgc ttttttaagt tcaatagtct ttttacattt aagcatagtt ctatcatcac
    18661 taaataaaag aatttgggat aatgcttgta aatcatttcc tttataaaaa ccattttcat
    18721 ttagaaattc ataacatttt tctatgtatt ctaaatcttc atctaaattt tttgaatgaa
    18781 ttgcaataag tgctatatta caatagtcat cactagaagt tagaaatgga tgttttttcc
    18841 tcatataatc atatattatt ttcatttttg atatacatgt aagataatcc attttctctc
    18901 tattttcata aactattgat gctgtaagtg gtaaatatgt atcgccccaa aacttttcac
    18961 ttttaagttc tttgtatata tctaaaatca tcttaaaact actttctgga tttgattcaa
    19021 acgaaagtag tgttgccata taaaacatat tatatcctct aaaattagag aataatccag
    19081 tatttttttt aataagctct attcgttctt ccactaatct aggacttatt ctcttgttct
    19141 taagggtaaa tgcaagtgca caactatgtt gtatcaatcc catttgccaa gaacctttaa
    19201 cttcatttaa tgctttgtaa ttttctatta ataagtttac ttttccattt ataaacgatt
    19261 gttccatatt gccctcctag taatatatct cattgtacta atagttttat atttattata
    19321 tatatattaa atactacaat caatacatat tacttcaaag aacatcattc ttcaacaata
    19381 atgtagcctt ttttgtaatg tcttcccata ttattgactc tatcatagta ctctgattca
    19441 ctttcattac tccatttggg cacaaataca tctattgcat tagaattact aaaatactta
    19501 ctagaccccc tatccataac agtttttaat tttccatcta caataatctt agttccaaaa
    19561 cttaagtgat tgtttgctac aaaaccatct tctaaatcat ctcctgtagc agttatcgct
    19621 ccatatccat tttcttgatt aagacttgtg taataactaa cttcaaaagt tataggtact
    19681 aacttcttta ttttaatacc taactgattt tgtagtttct ccttttgtac tttcaactta
    19741 tactcatcac tatttttata atcttccata ccttgattat acttggaatt aaagctttta
    19801 cctgacttta ctatagtatc tatatttact atagattctt tacaatgatc tgcatctatt
    19861 tttgtttctc catttaccaa taatggagtt aaacatacac tacatacaac acatgtaatc
    19921 aatgcttctt taagcttcat aaattccccc cttattattt tgatatatta gcatatttaa
    19981 tattatatgt ctacatttag atttaaatac cacacccatt tgctttaaga agttgtctta
    20041 tatttaattc accttaaaca cttataaatc ctctatctta gaatcatata gaataaagct
    20101 tttatcttta aatatttttt attaatcttt taaaatctaa aactacttta tctaattttc
    20161 tcttttttag aatttaagaa ttaaaattct ataattttaa aacatattga atttattttt
    20221 ttgagatgat ataattttct taagaggtgg ttgatatgat aaaaaataca aaacaaatta
    20281 cagtagaagt taatgaaatt ttattacaag aaatgtctaa gataactaat gacgaaaata
    20341 atattttgac agatttgata aatgaatcaa ttgtaaatta tattcttgaa aacaaaaaac
    20401 ataatattga aaataaagat ttagaagaag tgattaaatt ttacaaaaaa gaaaatactg
    20461 aaaaacctaa aagtgcagca agagctatag ctgaagcaaa aactcatact ctgtattaat
    20521 caaataaaaa agttcctaaa aactaggaac ttttttatat taataattat taatatatct
    20581 caatatttat ctcaaatcta tcaatataag catgtttaat acaatctatt gtatacttat
    20641 cttaccctag aaataatcaa aacaaaaata aaattatgcc ctttatatct aaaacaatta
    20701 atttacatga ttaatataca aaaattctga cttttaaatt cgtatacaat atcaaactaa
    20761 aataatatta atgacaaacc caatataaat taaattcaaa caggtttgat tttacatcaa
    20821 acttattgta ttaatattaa ataacaagac aaaaatattt ataaaaatca caaattttac
    20881 ataaaacttt atatttgatt catttaacta attattgtaa aaactattta ttttatgata
    20941 attaactaca ccaaattatt catctttttt aatatcctta acccattttt caacagagtt
    21001 caattcttct tcatttaccc cctttttgaa caaggatttc ataaaactct caatagaact
    21061 tccatgcata ttatctaaaa aagtttttgt ttcaaaatgt aaatactctt cttctccaat
    21121 aagaactgta taatgtgtat gtctatcaat ttttcttgca cttaagaatt gcttatttac
    21181 taatcttgat aaaagtgtta gtgttgtagt ttgcttccaa ttatatagtt tttccatagc
    21241 ttcaatgaca tcttttgatg ctactgtaaa atctgaactc caaataaatt tcatgacttt
    21301 taattctgct ggtggtatct tagtaatagt catatgattt tacactcctc tcaaacttct
    21361 acataattaa atactatatt aatagacttt tcgagtcaaa ggttttattt aaaatatctc
    21421 atccaaattt attaatacaa aaaatttata tttttattca aaattaaaca cacaatctat
    21481 taatataaag ataaatatct attctataag tataacagat tatcaaatta aaattctaat
    21541 atttgacata atatatacat tttttaaata aatatataca atgtattaaa atgtatgcaa
    21601 ctctatttca aaattatttt gtgatatata tatgttataa taaatgtata aaattttgat
    21661 tggtgggtta tatatgaatg catttattag aaaaagaaat aaaaactatg ttgtttacct
    21721 ggaatttgaa gatgaaaaga caggtaaaag aaaacaaaaa aatatgggta cttttgataa
    21781 aaaaagggaa gcaagtaaaa gactaaatga ggtaaaagaa agcttatata atgatggttt
    21841 tttagtacca agcgaaatta cagtgtcaga atttctatta gattttctaa ataaatatag
    21901 tgaaaatata tctttagcta catataataa ttatgttagt atttgtaaga attacattaa
    21961 tccatctatt ggaaaatata aaatacaaga cttacatcca gttcacatac aaaactacat
    22021 agataaacta tcttataaac taaatcctca atcaattaag attcatataa atatattgaa
    22081 acttgcaata aaaagagctt atagactcaa attaataaaa gaaaatgtta tggatagtat
    22141 agaggctcca agatataaaa aatttaaaaa tgagatttat gatagagaac aaatgataaa
    22201 attattagat ttagcaaaaa atacagaaat ggaattacct attaatttgg ctattggatt
    22261 aggtcttaga atttcagaag ttttaggtct aacttgggat aatattgatt ttgaagaaaa
    22321 tacaataaca gtaaataaga taacttcccg aattaatggt tctgttattc tcaaagagcc
    22381 aaagacagaa agctctgtta gaaaaatatc ttctcccaaa gaattaatgt ctttattaaa
    22441 agaatataaa ataaaacaga ataaaaattt attaaaatct tccattagaa ataataataa
    22501 tttgttgttt ttcaataaga aatgtgaacc tattgctgaa gatgttatga gtaaaaaatt
    22561 taaaagattt ttagaaaaga atgaattacc tcatattaga ttccatgatt taagacactc
    22621 acatgttact ttacttataa attctaaagt acctataaag gttatatccg agagagtagg
    22681 acactcaaat ataagtacta ctctaagcgt ttattctcat gtacttaaag aaatggataa
    22741 agaggcttct gacaaaattt ctgaaagttt atttaatgct aattaatatt aatttatctt
    22801 agctttaaat tagcttagct tattgagata gattcattaa tattaaatgt atctatctca
    22861 aattaataac tacttaaata atctgtttta ttttaattta tcgcctcagt tattatactt
    22921 ttttacgaaa aattatactt tacaataaaa aagatattcc cttatagaaa atatcttttt
    22981 aaatactata ttattatata cttgctaaca ttggaatatc taacatcttc ttcattacat
    23041 catctacttt ttttgcttta tattcattgt atccaattaa atatcctttt tcatatgaac
    23101 tttttaaaat ctctttttca tataaattat cagatttggc ttctgtgaca cttaaattat
    23161 aaagcccttt acacccatct tcataacctt tattataccc tttttctgca aaatagtttt
    23221 tatgattttt ttcgttatgt actgaagata ttgttactcc agaattttct tttgtactag
    23281 cataaggaca aaaaccttta ttgtgttgat gtgctgaatg tcctccacaa taataacgtg
    23341 ttaactctga tttattttta ttatgatgac ctcctgatga attatgccct cctgagtgag
    23401 catatgaaaa attccctaca ctaatcatag ctaaactaat tactacagct actaaccttt
    23461 tcttaaccat aatctattcc ccccaaaatg ttatatattt ttattatatc atctactata
    23521 ttatatttaa attcttaata tacaaaatat tactctattc tgctaataaa catgtttaaa
    23581 caacataaaa aacctcctaa tatttgatta aaaatttaca cactcatgca tagcatgtct
    23641 caaatattaa aaggttttat actaataatt atttatcttt tccatacatt ttagctaatt
    23701 ggtcttgtat ctctttactt tctaaatact catcaaagtc catttttcta tccattattc
    23761 catttggagt tatctctata attctatttg ctatagtaga tataaattca tggtcatgag
    23821 aagtaaataa aagcactcct gggaactttt caagtccttt atttacagaa gttatacttt
    23881 ctaggtctaa gtggttagta gggtcatcta atacaagtac atttgcattt gaaagcatta
    23941 gcttactaag catacatcta accttttctc ctccagatat aacttgagct tcttttaatg
    24001 cttcttcacc tgagaataac attctaccta aaaatcctct tataaaactt tcactttttt
    24061 cttcagagaa ctgtctaagc cagtcaacca aagaatattc tactccgtca aaaaacttat
    24121 tatgattttt tggaagataa tcttgagaag tagttactcc ccatttatac tctccactgt
    24181 ctggttcaag ttctcccata actatgttga aaagtgcagt agtagctatt tcatctccca
    24241 taaatactac tttatcatct ctatccaatc taaatgacac attatcaaga accttaaccc
    24301 catctatagt tttagttaaa ttgtgtactt ctaaaacttc attcccaatt tctcttgcag
    24361 gtgtaaatcc tacatatgga tatcttcttc ttgatggttg tatatcttca acttctaatt
    24421 tctctaactg tttctttctt gatgttgctt gtttagcctt tgaagcatta gaactaaatc
    24481 tagctataaa ttcctttaat tgagctatct tttcttcagt ctttttattt tggtccttag
    24541 ccaattgtaa agccaattga cttgactcat accagaaatc atagtttcca acgtacattt
    24601 gtattttacc aaaatctacg tcaactatat tagtacatat ttgatttagg aaatgtctat
    24661 catgtgatac tattataact atagattctt ctaaatccat tataaaatta tttaaccagt
    24721 ttattgattt aaaatctaag tggtttgtag gttcgtccat taatagtatt tcaggcttac
    24781 caaaaagtga ttgtgctaac aataccttaa ccttttcccc accaactagt tccttcattt
    24841 gtttgtaatg catatctttc gttatgccaa ggcccataag tattttctca gcattagttt
    24901 ctgcatccca tccgtcaagc tctgcaaact caccttcaag ttcggcagct tttatcccat
    24961 cttcttcatt aaagtcttcc ttcatataca atgcatcttt ttctttcatt atgttccaaa
    25021 gtctctcatg acctcttata acaacattta aaacagtttc ttcttcatat tcaaagtggt
    25081 cctgttttaa aactgacatt ctttctttat cagttataga tatactacct gtattaggct
    25141 ctatttctcc tgataatatt tttaaaaaag tagattttcc cgcaccatta gctcctatta
    25201 ttccatagca attaccttta gtgaatttta agttaacatc tttaaatagt tccttatcac
    25261 caaatctaag tccaacacct gtaacttgta acattaatat attttccttt ctttttgctc
    25321 ataatttatt ttatcataaa actttgataa cattt
//
LOCUS       DAEOTL010000052        24917 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEOTL010000052 DAEOTL010000000
VERSION     DAEOTL010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24917
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.052"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            117..1481
                     /locus_tag="KRH82_002521"
     CDS             117..1481
                     /locus_tag="KRH82_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBG8655794.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKIVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEECEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQKHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            1620..2786
                     /locus_tag="KRH82_002522"
     CDS             1620..2786
                     /locus_tag="KRH82_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBG8655795.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            2903..3685
                     /locus_tag="KRH82_002523"
     CDS             2903..3685
                     /locus_tag="KRH82_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBG8655796.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(3804..4457)
                     /locus_tag="KRH82_002524"
     CDS             complement(3804..4457)
                     /locus_tag="KRH82_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8655797.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(4481..5845)
                     /locus_tag="KRH82_002525"
     CDS             complement(4481..5845)
                     /locus_tag="KRH82_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBG8655798.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSIFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            6503..7933
                     /locus_tag="KRH82_002526"
     CDS             6503..7933
                     /locus_tag="KRH82_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655799.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            8036..9139
                     /locus_tag="KRH82_002527"
     CDS             8036..9139
                     /locus_tag="KRH82_002527"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBG8655800.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            9154..9390
                     /locus_tag="KRH82_002528"
     CDS             9154..9390
                     /locus_tag="KRH82_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8655801.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            9407..10456
                     /gene="vorB"
                     /locus_tag="KRH82_002529"
     CDS             9407..10456
                     /gene="vorB"
                     /locus_tag="KRH82_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBG8655802.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            10458..11198
                     /locus_tag="KRH82_002530"
     CDS             10458..11198
                     /locus_tag="KRH82_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBG8655803.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            11201..11740
                     /locus_tag="KRH82_002531"
     CDS             11201..11740
                     /locus_tag="KRH82_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBG8655804.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            11864..13963
                     /locus_tag="KRH82_002532"
     CDS             11864..13963
                     /locus_tag="KRH82_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBG8655805.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAVVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(14230..14745)
                     /locus_tag="KRH82_002533"
     CDS             complement(14230..14745)
                     /locus_tag="KRH82_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBG8655806.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLASVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14837..16048)
                     /locus_tag="KRH82_002534"
     CDS             complement(14837..16048)
                     /locus_tag="KRH82_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBG8655807.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            16724..18166
                     /locus_tag="KRH82_002535"
     CDS             16724..18166
                     /locus_tag="KRH82_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBG8655808.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            18208..18561
                     /locus_tag="KRH82_002536"
     CDS             18208..18561
                     /locus_tag="KRH82_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655809.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            18752..19573
                     /locus_tag="KRH82_002537"
     CDS             18752..19573
                     /locus_tag="KRH82_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBG8655810.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            19831..21714
                     /locus_tag="KRH82_002538"
     CDS             19831..21714
                     /locus_tag="KRH82_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBG8655811.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            21939..22619
                     /gene="pgmB"
                     /locus_tag="KRH82_002539"
     CDS             21939..22619
                     /gene="pgmB"
                     /locus_tag="KRH82_002539"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBG8655812.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            22616..24901
                     /locus_tag="KRH82_002540"
     CDS             22616..24901
                     /locus_tag="KRH82_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBG8655813.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYDEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYGKKYILEKCIKIDK"
BASE COUNT         9646 a         2797 c         4340 g         8134 t
ORIGIN      
        1 aagatttatg ttatattgag atgaatttat tatgatataa aaaataatgt taggataaat
       61 ttaaatcttt ttctaaaaat gtattaatat aattcttaaa gaaaggattt ttaacaatgg
      121 atataaaaga gttggttaaa atgcaaagaa aatattataa tacaggtaaa acaagagata
      181 tatcgtttcg tatagaacag ttgaagaaac ttaagttagt tgtatcacaa aatgaagaaa
      241 aaatactttt agcactaaag aaagatttaa ataaatcgga ttttgaaggt tttatgacag
      301 aggtaggcat gttttatagt gaattaaact ttgctataaa gaatataaga aaatggagca
      361 aaataaaaag agttaaatca agtatggtta attttccatc tatatccaaa attgttccac
      421 aaccttatgg tgttactctc ataatgtcac cttggaatta tccatttcaa ttagcactta
      481 taccattagt ttggtcatta gcagcaggga attgtgttat attaaaacct tctgaatatt
      541 ctgtgtcaac atctagtgta gttaaagaca tagttgaaga tactttttca aaagaatatg
      601 ttgcagttgt tcaaggaagt caagaagaat gtgaaaagtt actattggaa agatttgatt
      661 atatattttt tacaggaagt actaatgttg gtaaaataat catgaaatca gcatcagagc
      721 atttaactcc tattacttta gaacttggag gaaaaagtcc ttgtatcatt ttaaaagatg
      781 ctaatataga ccttactgcc aaaagactta cttggggaaa actaataaat gcaggacaaa
      841 cctgcgtggc tccagattat gttttagtgc atgaagatag aaaaaatgag ttaatagaga
      901 aaataaaata ttatactaat aagtattttg gggataatgc atgtaataat gagcaatttc
      961 ctaaaatcat aaatcagaaa cattttaatc ggatattatc tcttattgat aaagataaga
     1021 tagtctatgg tggaaattat aataaggaga cattaaagat agagccaact atagtagaca
     1081 atgttaattg ggatgataat ataatgaagg aagaaatatt tgggcctata tttcccattt
     1141 taacatataa agatttagat gaagtaatac aaaaaattat acaaatgcca aatccattgg
     1201 cactttatat ttttacaaaa aataagtacc tagaaaataa acttttagaa atgattccag
     1261 caggaggatg ttgtatcaat gatacagtta ctcatatagc tacgaattac ttaccttttg
     1321 gtggtattgg tgaaagtggt atgggctcat atcatggaaa agctggattc gatacattta
     1381 ctcattataa gagtgtgtta aaaaaattaa atttggatgt ccctattaga tatgctccat
     1441 acgataataa attaattaag gttcttaaaa agataatgta ggttatattg tagaataata
     1501 aatataaata aaattgagta tttgtattct gaatatattt tatttttaat ttggtatatt
     1561 tgttataaaa gtggtgattt tgtgataaaa tttaattata tagaaataag gaggaaaaaa
     1621 tgaaaattaa ttggaataca aaatacacaa caatagcaat ttatacattt ataatagctg
     1681 ctagtagtat tatattttat ctagtatcat cacaaattga tgtattttct aataatttag
     1741 atgctatatt tacaacatta caacctttta taataggatt tgctattgca tatcttctta
     1801 attttatttt aaagttttat gaagacagaa tttttataaa aagtgagaaa ttaaaaaaac
     1861 taaaacaaag ttcaaaaaga ggcttgggtc ttttattaac atatgcaaca gctacattga
     1921 tactttactt atttatgcat ttcgtattgc cacaagtaat tgagagtatt gttggactag
     1981 caaatgatat acctatgtat gtaaacaatg caactaagct tattgataaa ttaatgactg
     2041 atttaaatct tgatgagcaa tactttaatt tggcagttga taagtggaat gagtttgtta
     2101 catatattat aaagtttgta acagatttaa tcccaatatt aggaagtatg ttaaagaatg
     2161 tagcctctag tatatggaat attgtactag gattaattgt ttcagtatac ttattaattg
     2221 ataaagaaaa attctatgga ttaagcaaaa aaataactta tgcagtattt acagaaaaac
     2281 aagctgccag aattttagaa ttaactcata gaagtaacta tacatttgga agatttttag
     2341 gtggcaaaat attagattca ttcattatag gtattctaac atttgtaata cttacattag
     2401 ttaaaatgcc atatacatta ttaatatcag ttataattgg tattacaaat attatccctt
     2461 tctttggacc tttatttgga gctataccat ctacgctaat agtgatgttt gtatctccta
     2521 taaaagcttt ctggttattg ttaattatat taataataca acagatagat ggaaatatta
     2581 taggacctaa aatacttgga gattcaattg gtatatctgc attttggatt ttgttctcct
     2641 tattggttgc aggaaaatta ttaggtttta ttggaatggt tataggagtt ccaatgtttg
     2701 cagtaattta ttctataatt aaggatattg ttgaaagtaa attggacaaa aagggattac
     2761 cgacagatac ttccgattat atgtagctaa aaaatattat gtataattaa aaatatataa
     2821 attaagcaat atttaaagca ctgagaaagt taaactcttg gtgcttttta gatataaaat
     2881 tattatagaa gaggtgtttt ttgtggcatt tatagaatgt aaatttaaat ctaaatatac
     2941 tggaggagaa actgatataa ttgtaatttt gcctgtagca aatggaaaag aactttttag
     3001 tggtaaagag atatatgatt ttgaaggtaa atttaaaaca ttatacttat ttcatggttt
     3061 agaagatgac caaagctcat ggattagata tactaatgta gagcattatg ctaaaaataa
     3121 aaatatagcc ctagtaatac caagagtaga aactagtttt tatactgata tggcgtatgg
     3181 acaccaatat tttacttttg taagcgagga attacctaaa tttgttagag ctatatttcc
     3241 tttatcagat aaaagggaag ataactttgt agctggtatg tctatggggg gatatggagc
     3301 tttaaaatta gcgctttcaa aaccaaaaga gttttcggca gttgcaagtt tttctggttc
     3361 gcctgatatg attcatgagt tagaaaatca acaaatagaa accaatgcag acattctatt
     3421 tcacgatttt ggtagaccag aagacgctag aaatagtgag aatgatttac tttacatact
     3481 taagaacctt aaagaaagaa atgaagatat tcctaaaatt tatcaatttt gtggtgatag
     3541 agatttttta tataaaaata atcagatgtt taaaaaatat gcagattctc tgggtgtaga
     3601 tgttgaatat gaagagtgtg taggggggca tgaatggcgt ctttggaatt tatggataaa
     3661 gaaatttata gatataattg gatagtacac ttatggtatt aacaggtata ctataaaata
     3721 tctttaaata tgataaagac tgaaatccta aaatcaaatt atgattttaa aatttcagtc
     3781 tctaagaatt taataaaatt ttattaagtt cttacacgag ttattattgg agtaaaattg
     3841 tcaactatat ctatatagta tttactcaat tcctctaaaa tctcttcgca taaatccgta
     3901 ctatgaccaa gattaataag aaactgtttt gtaaaatgct ttattacagc ttgagaagat
     3961 atatcgtact tgtgtgaagt ataaactcta attatttcag gtttcatagc aagtatacca
     4021 atacaagaaa gtattaattc atcatgttct atagattctt tatcattaac atatcttttc
     4081 atgaccattt cggttacact tctttgatag cttaaaatag cttcttcata agctatatcc
     4141 aaataaaaat ttctatatgc ttcgtttttt agaaggaaac aaaggtcagc attcatagca
     4201 agaaagaaca tcatcatagt accttcttca tggtagttat agattaaaga ctgcatttca
     4261 tttcttatat cttcatatat tatagctcct atttcgcttt tacttgagaa gtaatagctt
     4321 attagaccta aatttatatt agctctttct gcaatttgcc tagttgttgt cttatgataa
     4381 ccttgctcaa aaaataattc tctagcagca cttataatac tagcttttgt ttctttgccc
     4441 ttttctgatt ttgacatatt tactgtgtat acctctcttt tcaatctttt tttgaaaatt
     4501 tgctaactat aaatattgta atagaaccac ctattatagg aaccaaaatt ctgtcaaata
     4561 cagtaagaat accaatcata tttaataatg ccaatataac acttactata acagcataga
     4621 tagctccttt ttttgtagca cctttccagc aaagaccaat tacaaatggt gcaaatatta
     4681 cacctgtaca taatggagct ggccaaaaca ataattctaa taaactatca aatttaagtg
     4741 ctatgattgc acctattata gctgtcaaag ctgatgcaat ttgagaatac tttagagtat
     4801 tttttaaatc attaaattct atattaggat gtaataattt gttataaata tctcttgata
     4861 taatagcact cattgaggtc attaatgaat cggcagtaga cattatggca gccaatatag
     4921 cagctaagaa taatacagat attaaaggtg gtaaagtagt cgatatcatt tgaggtaaaa
     4981 cctgaacaga tgatatattt ggaaataaac taccaccaat agctccaatt attcctatag
     5041 ggaaagcaag aaataatagt ataaatcctg caattacact acttttaact gcatttttag
     5101 cattatcagc acattgatat cttaaaaaac tttcataaga aaatattgag cctaaaacta
     5161 atggtaaaac tgtatacata aaatcactaa tcgatttatt tcctggaaag aatggttctt
     5221 ttaccattga ttgtaacata agtaaagggt tgtcgccaac taattttaag cttatataag
     5281 ctactattgg caaaaacact atacaaatag caagttgaat aaatgctgat actgcaactc
     5341 cccacattcc tgatgtataa gtatatataa tgataactat aactcctata attacagcta
     5401 tatcataagg aataccaaat gcagtagata cagaaccaaa agaaattaat tgactaccca
     5461 taatagctag tatagatatt ggtgttacaa gactttgata agctcttaaa aatatactat
     5521 gaccatatct agtttcaata taatcagcag gtgttatatc acaagataag cttcttaatt
     5581 ttcctgcgaa aaatgcattt ataaagcaag ctaaagctgc acctatagta gaatacattc
     5641 caacccaaag tcctctttca gctccccatt gaactccacc aactaagcac cctcctccaa
     5701 aagatgtagc agcaatggtt gcagctagta taggcaaagg cagatttcta cctgcgatta
     5761 ggaaatcgga tgctgtttta actttttttg aaaaataaaa accaatccat atgtatattg
     5821 cacacgtaac aattaaaagt aacatagtct tttctccttt ataaaatatt ttaataaaat
     5881 atacaaaata tatttaaaat atattttata taaaagtagt acgatatttg ttttattggt
     5941 tttagattaa tatagctata ataatttatg atattagatg gaaattacgt aaaaatagaa
     6001 aattgaaaat tctgaaattt ttgcatattg atatttatct catagattct tttttgtaat
     6061 tgtaacacgc ttttattttt aaatcaatag tacatgtata aaaataaaag gaatttaaat
     6121 aagaaaaaga tatttttaat atctggatgt agtatagaaa tatcttgaat aaattattct
     6181 tgaataaaat tataaaaaat taaaatcact agaaatatga taaaataatt taaaatacgc
     6241 atttcaatga catttcaaaa caagaaaata ataaaaaaca aacctaaatt aagtctaaat
     6301 agctttttag ttaattttag tagtaaaaaa taaaacttaa aaagtgtttg acaattatga
     6361 attttgagaa tataattaaa ttaaaattat acacatataa aaatatactc ctgaatcaag
     6421 aatgagatat ttaagattca aaatatatat tattatacgt gaataataaa aagtaagaaa
     6481 attttataag ggaggggtag atgtgagtag tcaagaaagc aaaccaaaag gaaatcttat
     6541 atcaaatttt agagatgata tgagagaccc taagaaaaga gcaatataca catattcaag
     6601 ttctataaac ttagcgtaca attttatagg ttactttgta tcaactgtta caaatatttt
     6661 tttaactgat gtggcaaaac ttggtgtaat tatggcaggt ggtatgcaaa ttatacaatc
     6721 tttcataaaa attgctgtag ctcctataac aggtacagta tttgacaaac aaccattcaa
     6781 aaaaggaaag tattatccat ggcttagata tgcaccagca gcgttagcat taacatatgg
     6841 aatatttttc atagttccat taatgaaaat aagtccagca ttacttttac ctttgatgac
     6901 agctttatta ttaatagcat cttgtgctca gcaagtagtt ttcactataa tttatgctat
     6961 ttaccctgta gttgctaaga cacctagaga ccgagttata ggctcaacta ctacgaatat
     7021 atttaaagaa gttggtaaat tcttagtagg tttttcatat ccgttattat tagttttatt
     7081 tgcagatgta ttaggtggag aaggaatggg ttatttaggt acctacttat tctttgcagc
     7141 aggatgcctt ttagtatttt ggttttcttc aacagagata ataaaatctg gagcagaaga
     7201 agaagttctt caaaaagaag agaagccaaa gattaaagca agtgaaatgg caaaagcttt
     7261 attcactaat gtaccactta tgatggcatt ttgtttagaa tttcttatat gtataagatc
     7321 tataggatta ggacctttgg ctccatatta ttttaaatat gtaatagaag atgaacgtgg
     7381 attagcagta tttttatcaa tcatgccttt ggtaagtgta gcattcatgt ttttcgcacc
     7441 agtgtttata aaaatctgta gagagcaaaa actagcttca ataatttctt tttctatatg
     7501 tgcactatgc cacttattgg ttgcatggac tccttggggg aaaactactt taggagtaac
     7561 tatgttgttg gcaattggtg gaggtttttc aaatgtagta tcaataataa atcttaattt
     7621 ctttgccggt tcttgtgatt atgggcattg gaaatcagga aaagacttac ctggcttaag
     7681 tatgtcacta tatccagttg caatacaagt aggagtatta cttgcaacta ctataagaac
     7741 agttttaatg aactcaatgg gatatcaagc tgatatggta gtcacagaag cagttaaatc
     7801 aggttttata aatatgattt cttattctat ggcaatacct ttaataatag ctgttgttat
     7861 agcaatacta tatccagtaa gtgacaagaa attaaaccaa ataagagaag agttaaatca
     7921 aagaaatgct tagttaaaag aaagttaagt agatggttaa tttaagctat taaagtaagt
     7981 agacgcaata gcgtttatat aaatgaaaat acatatacag agggggcttt taaaaatgat
     8041 agaaaaatta ttgagaaata ccgtaaaaga attacatcaa tatgttccag gtgaaccaat
     8101 agaaaaagtt aaggaaaaat atggtgtaaa agaaataata aaattagctt caaatgaaaa
     8161 tcctctagga ccatcaccaa aagcaataga agctatgatt gaaatgttaa aacaaggtca
     8221 actttatcca gagccagaag ctaacgaact tagaagaaaa ttagctgaaa agttagattt
     8281 aaaaccagaa aattttattg ttgctaatgg tgcagataac gttatcactc taataggtga
     8341 ggcttttata aatagaggag atgaagttat atattgtaac ccaacatttc catcatatag
     8401 aactgcaact ataaaaaatg aagggatacc agtagaagta cctttaacag aagattataa
     8461 gtatgattta caaggtatat tagataagat tacagataaa acaaaattaa tatgtgtatg
     8521 taaccctaat aatccaacag gaacaattgt ggatgataaa gagttagaag aatttttaaa
     8581 gaaagtccct gaaaatatta taactatatt ggatgaagca tatatagaat ttttaacagt
     8641 tcctaattat gtggatggac ttaagtatgt aagggaaaat tataacgtta tagtaacaag
     8701 aactttctct aaaatatatg gtcttgcagg gcttagagta ggatatggta ttgctaaaga
     8761 tgagataata agaactttat ttacagtaaa agagcctttc tctgcaaatc gtgttgctat
     8821 aagtggagca acagcagcac ttgatgatga agagtttata aaagaaacat atgaattaaa
     8881 tagagttgga atggcttact ttaaagaaga gtttacaaaa atgggatttg atgttgtaga
     8941 ttcacaatca aatttccttt atgtagatat gaaaacagat atacctaagt tatttgaaga
     9001 cttgaaaaaa agagggtttg taataagacc aagtgctaca catgcacgtg taagtattgg
     9061 aactatggaa gaaaataaga aatttgtagc agttttaaag gaaatattaa atattaaagg
     9121 agagccaagt attggataat agatagaaat attatgaaac ggggtgtaga tatgaactta
     9181 aaaataaacg cagagagatg taaaagttgt gaatactgcg ttatatcttg taaaaaagga
     9241 gcattaaaaa tatcaagtaa gataaataaa gaaggttatg ctcatgtaga agttgatgag
     9301 agtaaatgca tactttgtgg aatttgctat caggtgtgtc cagataatgt ttttgaaata
     9361 attaaagaag aagcatgtca agaggcttag aaggagttgg gataatatga aaaagatgtg
     9421 gaaggggaac cacgccattg cagaagcagc cctaagagga ggttgtgaat tttatgcagg
     9481 atatccaatt acaccacaaa cagaggtaat ggaattttta tcacatagaa tgtctgaact
     9541 tggaagaact tttatacagt ccgaaaatga gatggctgct atatatatgg tatatggagc
     9601 atatgcaagt ggaatgaggt ctatgacgag ttcttcagga ccaggaatat ctttaaaaca
     9661 agaagggatt tcttacttat gtgcaaatca ttacccttgt gtaatcgtaa atgtacagag
     9721 atgggggcct ggtcttggct cattggactc agcacagaca gactatctaa gagatactag
     9781 agggggagga aatggagatt atcatttgat agtttatgca ccaaacagta ttcaagagac
     9841 tgtagatttg atgtataact catttgatgt agcggagaag tacagagtgc ctgttgaaat
     9901 tttgacagaa gcagctttag gtcaaatgat ggaaccagta gaatttccag agtttaagaa
     9961 gagagaagga gatttaggtt ggacttatga tggaagtaat agagaccatg caaaggttgc
    10021 agataaccaa aagccaactt tttgtatgga gaaacgtatg agaataactg aaaatgaaca
    10081 acaatgggaa gattatcaag tagaagatgc agaatatgtg tttgtagcgt tcggtatacc
    10141 atcaagaaca actatgaatg ctgttagaag acttagagaa caaggtgaaa aagttggaat
    10201 aataagacca ataacagtat ggcctttccc atataaagca tttgaaaagg taagtaaaga
    10261 tgtaaaagga tttatctcag tagaatcaac agacacaggt caattagtag aagatgttgc
    10321 tttagcctca aagaaagtat gtaaagaaaa tgtacctgtg tatggtttat ttagtggaaa
    10381 tcatatacca aaaacattgc aagtaatgga cacttatagc aaaataaaat ctggcgaaat
    10441 caaggaggtg ttctaatatg gctacagaaa aattaacacc tagcgttgtt tcaataccaa
    10501 acaagttttg cccaggttgt ggtcatggaa tagtaaatcg tataatagca gaggtaatag
    10561 aagaacatgg atatgaaaaa aatcatgtat taacattagg agttggttgt gtctgcaata
    10621 tgaattttag ctggaatggt gataagatgc aaactgcaca tggtagagct tcatctacag
    10681 ctataggagt taaagtagca cttccagata cattagtaat gacttaccaa ggtgatggag
    10741 atgcttatgt tataggtctt tctgaaactt taaatacagc atatagaaat cataatgtga
    10801 ctgtatttgt aataaacaat aataattttg caatgactgg tggacaaatg tcatggacca
    10861 ctatgccggg tcaagtcaca acaacaagtg taaatggaag agatataaag actactggta
    10921 gtccactgaa agttcctgag atggtggcaa acttctttga tgtagcgtat gtagcaagag
    10981 gttcagttca tagcccaaag gaaataatta atctaaaaaa atatataaaa aatgcaatag
    11041 aagctcaatt aaatggagag ggatattcct tagttgaaat attagcacct tgcccaacta
    11101 actggggtgt atcactagag aaatctatca aatggatgga agaagaaata gtgccatatt
    11161 atgctcttgg cgaatttaag caaagggatg gtgaatagtt atggaaaaag agctagtatt
    11221 tgcagggttt ggtggtcaag gagttttaac tcttggtctg attgtagctg agtcagcact
    11281 tgaattgggg aaacaagtaa cttggatgcc tgcatatggt ccaactatga gaggtggaaa
    11341 agcctatagt gtagtaaagt tttctgatga gagtataggt gggcctgata tggaagaaat
    11401 agatgtttta gtagcaatga ataaaccatc tttagattat ataaatttag ttaaagaagg
    11461 tggaacagta gttattaata catctgcaat agatgagaat gtaacattaa gagaagatat
    11521 aagtgtagtt aaaataaatt gtcaggaatt agctcaaaaa gtaaacaatc caaaagcagc
    11581 aaatatagta gtacttggag cattaattgc taaaactggg ttatttgaaa aagaattagc
    11641 tttaaaaact atgtgtgatt tctttgagga aaaaggaaaa ggaaagttta atgttcaaaa
    11701 tgaagcagca ttcatggaag gctataataa cgccatttga taaattaccc ttatcttaag
    11761 tgatttatct caagatttaa taatctttag tgccaagaga aacttcatct tgagataaaa
    11821 ttcacttaaa atcacaacta taaacatata ggagcgtgaa tttatgagtt tggaaaaact
    11881 tattagacca aaaagtattg ctatagtagg agtgactgat aaacttggtt ttggaagaag
    11941 tgcagcactt agtatagtaa aaagtaagga aacagataga gtatattatg ttaatcccaa
    12001 aagagaagaa ttgtttggga gaaaatgtta taagacgata caagaagttc cagaagtagt
    12061 agactgtgta gtagtatgta cgcctagaaa tgtagttcca tctgtattaa aagattctgg
    12121 agagttagga acaaaggcag tagtggtata tgctagtgga tttgcagagg aaggtacaga
    12181 ggaaggtaca gatttagaaa atcaacttat agaaatatca aatacatacg atatgaaaat
    12241 attgggtcca aactgcatgg ggttgctaaa ttgtatagat aaggttaatc tatgggcagg
    12301 aggttctaaa tgggatttag atactaaaaa acctggtata ggaattgtag gtcaaagtgg
    12361 atttataact gctgaaattg tttcaagtga ttattttaat atatcttatg gtttttcaac
    12421 aggaaatgga aatatagtta cactagaaga tgcagtagat ttccttgtag atgatgatta
    12481 tgcatcagta atagcaattt accttgaagg tttaaaaaat cctcaaaaat ttatagatgc
    12541 tttaaaaagg gcagcacaaa aaagaaagcc agtaataata ttgaaatcag gaaggtcaga
    12601 aaaaggtgct atttctgctg cttctcatac aggaaattta gctggttcga gtaaagcttt
    12661 tgaaagtatt tttgaaaaat atggagtaat ttctgtggaa aatttagaac agtttatgtg
    12721 tttagcacaa gcttttagtg ttttagatgg taatttacct gcaaattcta attttgcagc
    12781 aataaacttc tcaggaggag aaaatactat ttgtgcagat ttagcagaag aaaatggtgt
    12841 agaacttgca gaaatatctt ctgaaactaa agaagaaatg aaaaaatatc ttccaggatt
    12901 tgcaacacct aaaaatccac tagatgctac aacagcatta ttccatgaaa aggatatgat
    12961 agtaggttta ttacatacct ttgaaaagga tgatagtgtt ggatttacta tggtaggtgc
    13021 aaatataaga gatgaagaaa atgaaatgca tgaaaccctt tgtaaagctg taagtgaagc
    13081 tagagaacaa ggattgaaaa aacctgtgtt tgcagttcct acacttgaag gaaatagata
    13141 tttagattat aggactagat tagaagataa tcaagtgcct ataatgtcat cagttggaac
    13201 tacatttact tgttttaata aaatggctaa gtttatagat tatgattatt caaaaagaac
    13261 tttagaattt aaagctgtta agaaaagaga gtcaaataat gtagtagcat tatcagaatt
    13321 agatagtaag attgagatga aaaaatatgg agtaccagtt ccaggacaag gtaatgcaaa
    13381 aagtattgat gaattagatg aaatcttaaa atatattaag tatcctgttg ttttaaaaat
    13441 aaattcttct gaaatattgc acaaatctga tgttggagga gttaaaatag gaattaagaa
    13501 tagagatgag gcagtagatg catataatga gattttaact aatgtaaaaa aagcaaaacc
    13561 agatgctaat attgatggta tattagttca agaaatggta gaaagtggta tagaaattat
    13621 tattggtata actaatgatg accaatttgg accaatgtta ttagtcggtt taggaggagt
    13681 atttgtagag gtatttaaag atactacatt atatccatta cctataaatc atgatgaagc
    13741 tattatgatg cttaaaaaac taaaatcatt taagctttta aatggctata gaggaagtga
    13801 gccttgcgat attgatgctc ttgcagatat gatggtcaaa ttaggaaaat atgcttatga
    13861 aaataaggat gaagtcaagg aaatagactt aaatccagtg tttgtatatc ctaaaggaaa
    13921 aggcgtatgt gcagtagatg ccttaatagt taaatataaa tagtttataa gttttggtat
    13981 tcaaccataa ttaaagcacc gactgaaaat cacattttgt aagttagata gtgtgatttt
    14041 cagtcacccc aaatttaatt taaaaatatt ttaaaatgaa agtatagttt taagtttcat
    14101 tgtgaaatag cactgtataa acaataaaat actacgtata aaacgaataa taaaaggtgt
    14161 tttaatgata agaatcaatc ttgattttca ttaaaacacc ttctttatta tattaaaaat
    14221 ttttaaacgt tatattgtca caggtgggtt tgttggagct gcatatgtac gattagcaaa
    14281 ttcttggtca acaaagaata gaccaccctc tccggcaagt ttaacacgtt ttatattgtc
    14341 ttcacaattt gtctcttctt ctgcttgttc agatataaac caaagtaaga attgagaagt
    14401 tctaaagtct gattcagagt ttgctacaga tgctaagttg tttattaaag ctgtaacctt
    14461 tttttcatga gctaacgtac gctcaagaat atccattgca gaagtaaagt ctgaatctgg
    14521 cattgggata gcatcaagtt gaacctttcc tcctacatta tgtaagtatt tgtaaaaaaa
    14581 catagcgtgg tctgtctctt ctttatattg aacataaaac caattagaaa atcctttaag
    14641 tccttctgct tcaaggtaag aagacataga aagataaaga tacgcagaat ataattcatg
    14701 gttaatctgc tcattaagta atttttccat tttagctgaa atcattttta tacctccaaa
    14761 ttttaaatgc tcttataaaa tataataata ttaaatggaa aaatattcaa taaaagtgtt
    14821 taaatatttt acatatttaa taaaaattta tactaccatt aaaaaaatta taacttacaa
    14881 tggctataga gccaattaat ggtgcatttg ctccaaaatt tgaatgcctt acacttattt
    14941 ttttatattt agaaaaactt gctgaagcag tcaatttttt taataatgta ttttctataa
    15001 atgtaccagg tatattaaag tcatagccta ttattataga actacaatca atcaatgtaa
    15061 gtgtattaac taatgcatat gatacgtatg tacaaaattc atcaagcaaa aacatggcaa
    15121 gactatcttt attatttgcc tcatctatta acttgactaa agaaaaatct ttacagttaa
    15181 ttaatgggga gttaggataa atatggctca atgattcaat tcttttaatt agattactga
    15241 cacttgtata ataatctaaa catccattgt taccacaact gcacaatggt ccactaaaat
    15301 taattgatgt atgtcctatt tctccacttt gtcctaggtt gccagtatga agtttatttt
    15361 ctagaactag accagctcca ataccattca ttatgtgtag gtatatataa tttgatatat
    15421 ttttacctaa accatacatt ttttctgcta atgcacccga attagcatca tttatcaaaa
    15481 atattggcaa atcagacatt tcttttataa aatctactat atttaggttt gatacatttc
    15541 caaaatctgg gggatttagt atggtaccat ttatatcatc tactggacct attgaagaaa
    15601 taccaattcc aattatatct ctcttgttga ttttcattat tttagtaaac attcttttta
    15661 ttatatcttt taaaacatca tttgatagac atttagggta agtttcagaa agttgtttta
    15721 caatattacc ttttaaatct gaaataatta ccttacatat atttcttctt attaggattc
    15781 cacaaataca aggcgatata ttagaaatat ctaataaaat gggtttacga cctgatgaat
    15841 gtgcatttaa agttgatgac tctatttccc taatcatatt ttcattaata agttcagtaa
    15901 ctagatttga taaagtcatt ttagtaagtc ctgtagactt agctaaatca actctggaca
    15961 taggtgtatt tgtagaaagt aatttcaata ttattaactt atttttaatt tttacatctt
    16021 tgatgttaga accttgtttg ttactcatca taaatctcct taaataaagt taagtgtttt
    16081 atttattttc aagtatacta tcaccttata atagagtaac atttttttac ttgaaaatat
    16141 cattaattag aatatatcac attatatatc ataaaatata taaaaaaatg ttagaattaa
    16201 attaaaagtg aaaagtagat tgatatataa atagtaaata cttaattaaa aaaagataat
    16261 gatagcaata attattgtta ccaagaatct actacttcaa gtgttacctt aggtatttaa
    16321 gttgatagtg gtttgcacgt aataaacttg atgtaatata tattcttaat aatattgata
    16381 aaagatttac ttaaaaataa tatagattat gtaaacatat aatctattta ttgtatacaa
    16441 taaaatttca ttttgtaaaa cagtgaatta aatatgtaat atagatatcg atttttatta
    16501 caaattgtta ctaaatatag gtacattaga acaaaaatct agtaaattgt aactaaaatg
    16561 taaatttttc ctttaatcta tacaatatta tggaaacttt ttgtaattta tgatataata
    16621 acaaatatat aattattaaa ttataataaa tgactatagc gtagatgtaa tactatgtta
    16681 tagtcatttt tgaattaaac ttgatatatc aagggggaag aatatgagaa caattagaag
    16741 agttttagca ttaggtttaa cattagctat atttctaata aatgtaccta atgtagatgc
    16801 attaacatca gatacaatta aaggtaacaa tatatatgag acggctggat taatagcaga
    16861 taaaaagagt tatgatacag caattatggt aaatatggat aattctatag cagatggtct
    16921 ttcagcaagt ggtcttgcag gtgctgttga tgctccaatt ttgcttgcac aaaaaaataa
    16981 gataccaaat gaaacaaaac aaagattaaa aaatgttaaa aagatataca taataggtaa
    17041 agaattatca ataagtaagt cagtagaaac tgaactaaaa aacacagggg cacaggtaac
    17101 tagattgggt ggagatgaca gaataaagac tagttatagt gttgctaaag aggtaaatgg
    17161 tatcaaaaaa gttgatgaag tgatattaac taatgcatat aaaggagaag cagatacaat
    17221 aagtgctgca cctgtatcag taagagatat agctcctata gtacttacag atggaaagag
    17281 tgtgcctttt tcaacaagta atgtaaaaac atatgcagta ggtgggagta tatcaatgag
    17341 cactagttta gttaataaaa ctaatgctaa aagacttggt ggttcagata gatatgatac
    17401 aaataagaaa gttataaaag agttttatcc agatgcatca gaattttatt tgagtgatgg
    17461 atatgattta gtaaatgcac ttacaggttc tacaattgct aaggaaaatc caattgtatt
    17521 ggtgtcagaa agtagtgata agtctatatt agcaggagca gataagatta ctagattagg
    17581 ttcaataagt gacagtgtgt ataataagtg tgtttctgct gcacaaaata atggcgattc
    17641 gtctacaaaa ggtgagtcac ctatgaaaaa tgagacaagc atattaggtc agccaacagc
    17701 tagtttagaa gcgtgcttaa aatgggcaaa atctaaaaaa gctaatgatt tatttataga
    17761 gttaatacca atattatatg atactgctgt tcaggaaggt gttaatcctg ttttggcagt
    17821 agctcaatct gcaaaagaaa ctggtttttg taattttggt ggagtattag atgcatcatt
    17881 taagaatcct tgtggactta aaacttctgt aggtggttct gatactgata agaatgccca
    17941 ttcaagattt gatacttggg aagaaggaat attagctcaa attcaacatt tatgcttata
    18001 tgcaggacaa gatggttacc cactttcaaa tccagtagac cctagacatg aaaaatcttt
    18061 atttggtaag gctaaaacag ttgaaagttt atctaataat tgggctggag gtcaatatgg
    18121 acaagattta gtaagaatga tgggagaaat tgaggcaaca aaataattga agattatcaa
    18181 atatccaata aataaggatt gattattatg aaaaagagta atatttttag tatcatattt
    18241 cctacagtca taatggtgct aatgttttta acttttgcta cagatatatt taatattcca
    18301 gatattcaat ctaaaagtat ttttgttgtg ggaatggttt tgatttttcc aatttctttt
    18361 ttgatacaag ggataatttg tgtattaaat aagactaatt ggattttatc tcttattgtg
    18421 tctttagtaa cttatatagt attaatgtat atatttttaa atgattctgc atatatatat
    18481 gttttacttt atacagcttt ttatatgatt ggacatataa cagctaaact ctattacaaa
    18541 attaagactt ttaaaaatta aattgaagta tataaaagta acattaagag aagtatcctt
    18601 aatgattttc taaaatcaga aataggtgct tctctttttt gtaaaaataa aagtatgtaa
    18661 ataaaattta accattataa ttttctttta acaagtgtat acaataaact tgttgtataa
    18721 ttaagataga taaaataaag ggagggataa tatgaattta atagataatc atattcatac
    18781 taatttttca agtgatggaa aggattccat ggaagataca ataaaaaaag ctataagtat
    18841 tggtgttaga tatttgactt ttacagacca tttagaacat gatgaagata gaggattttg
    18901 cataaattat aatgactatg ttccagtatt taataagttt aaagaaaaat ataaaaagga
    18961 catagagtta ttactaggtg ttgaagtggg ttacagaaaa catctaaaaa atgaaataga
    19021 agaaataata aattctaatc cttttgattt tgtattgtgc tcaactcata caattgacaa
    19081 tgtacctgtt ccatcaaagg cgtattttaa aggtcttagc aaagaagatg cgtattataa
    19141 atattttaat agcatacttg aaactaatcg tgaatttgga gattacaata tatatggtca
    19201 tttggattat atatctaggt atggaatata ttcagataat agagttatat acaatgactt
    19261 taaagatgtt attgatgagg tcttaaagtc aataatcaat aatgggagtg gtatagagct
    19321 aaatacttct ggttatagat atggactaaa tgctatacat ccaaatgaag atattctaaa
    19381 aagatataaa gaacttggag gatttatagt tactgtaggt tctgattctc atagggtaga
    19441 agatatatgc aaagattttg atgtggccta tgatatgctt aagtatcttg actttaaata
    19501 tgtatcttta tttaaagaaa gagaaactta ttttgtaaat atagaaaaag ttaaatctaa
    19561 caatatagct tagagtgtgt tttgaagtaa attaatggat agttaaaaag ttaatagtta
    19621 taatattgta tcctctagaa aaatactaga ggtttttatt ttgctaaaat aactaaatag
    19681 aattaaattt aaatagtata gcttatttta aattgaatag tttattgttg atatatttta
    19741 ctattatata tttttattgt gatataatag taaaatatat taacctatct ttagattata
    19801 taaattatta taaaggaggg aaattttaaa atgtctaata aaaataaaga aaatataact
    19861 ttaagtaatc aaatcaaagg aacaattcaa aatagtttaa caaaagaagc tatattacat
    19921 ataccaatga gcaattatgc ctatggttat gatagagaaa cactacatat aagacttaga
    19981 actaaaaaaa atgaagcgaa aagagtaatt ttacgaatag gagaccaata tgtgtgggat
    20041 aaaggaggtg caggaggagg aaatttaaat gcatctggag ttggttggtc tggtggaaca
    20101 aatatagtaa tgagtaaaga agtagaaact gaattatttg actattggat agctaagtgt
    20161 aagcctttaa ataaacgctc acgatatggc tttataatag aaggtcaaga ggaaaaactt
    20221 ttatttacag aaaaaagaat aatagagttg ggaaatgaaa atgatgaaaa ggaattatgt
    20281 gaaataggta atttttttgg atatccatat ttaaattata tagatatacc taaagtgcca
    20341 aattgggtga aagatactgt ttggtatcag atatttccag atagatttgc aaatggtgac
    20401 ccgtctataa acccagaagg agtagataaa tggggagcta ttccaaccag agataatttt
    20461 acaggtggag atttacaagg tgtgatagaa cacttagatt atttgagtga tttgggaata
    20521 aacggaattt acttttgccc tattacaatt ggaaaaacca atcatagata tgatacggta
    20581 gattatatgg aggtagaccc tacattagga gataaagaga ctttaaaaaa actaatagaa
    20641 gaagcgcata agagaaatat aaaaataatg ttggatgctg tttttaatca tataggatat
    20701 tattctaaac agtggcaaga tgtagttcaa aataaggaaa attctcgata taaaaactgg
    20761 ttttatataa aagatatgag taaaattgat actccaatag aacaaataga tgaaaaaaat
    20821 ataccttatg aaacctttgg gtgtgaaaaa tatatgccta aacttaatac agaaaattca
    20881 gaagtaataa aatatttatt ggatgtaggc aagtactgga tacaggaatt tgatatagat
    20941 gcgtggagat tagatgtttc aaatgaagta gaccatgttt tttggagaaa gtttagagaa
    21001 gaagtcaaaa aagtaaaacc agacatttat atattgggag aaatttggca tggtagttta
    21061 ccatggctaa tgggtgacca atttgattca gttatgaatt acttgatgtc agaagccatg
    21121 aaaaaattct tttgtacaga tgagataaac gccgaagaat ttaagtatat gataaatgat
    21181 gtaatggtaa gttatccaat acaagttagt gaagttattt ttaatttact tggaagtcac
    21241 gatactacaa gaatattgac ttatgctaat ggaaatattg atagatttaa acttgcatat
    21301 atgtttatgt ttgtacaaac aggatgtcct tgtatatact atggtgatga aatcggaatg
    21361 gaaggagaat taagttcaat atctgaaggt caaagaaaat gtatggaatg gaatgaagaa
    21421 aaatggaata aggatatatt tgattttatg aagaagatta ttagacttcg taaagaaaat
    21481 aaagaactta ggtctatatc aaatgaatgg gtgttagcag ataaggaaaa tggaacgatt
    21541 atattgaaaa aagaatctat ttctataata ataaataatt catctaaaaa tataattttg
    21601 acgttaccag attatttagc aaataaaaaa gtaaaagatt tatatgaaga agaaatagtt
    21661 gatttaaaag aagaactaat gttagagaaa tacaagttca ttattttaaa ataatacaaa
    21721 aaagtattta ttttagattt catgttaaat tattatacag tttaaataag tctttataaa
    21781 cgataaaaaa atatggtcta caagtgagtg aattgaaagt agattttaaa ttaaagactg
    21841 agttagagta gataatttta taaataatat cttaaataca agatagaaaa taaattgatt
    21901 attagtctaa aaatttcttg tagaaagagg aaataagaat gattgaagca tttatatttg
    21961 atttagatgg tgtaattaca gatactgcat attatcacta tatggcttgg agaaaactag
    22021 cccataaagt tgggatagat atagacacaa aatttaatga atctttaaaa ggcataagta
    22081 gaatggagtc attggacagg atattagaat ttggaaataa gaaatattca ttttcagaag
    22141 aagaaaaagt gagaatggct gaagaaaaaa ataattacta tgtatcattg atagatgaga
    22201 taacttcaaa tgatattttg ccaggtatag aaagcttgtt aattgatgta aaatctaata
    22261 atataaagat aggtctatct tctgcaagta agaatgcaat aaatgtatta aatcatttgg
    22321 gtataagtga caaatttgat tttatagctg atgcaggaaa atgtaaaaac aataaaccac
    22381 atccagagat atttcttatg tcagcgaaag ggcttaatgt aaatccacaa aattgcatag
    22441 ggatagagga tgcaagtgca ggtatagacg ctataaactc agctaatatg ttttctgttg
    22501 gtgttggaaa ttatgaaaac ttaaaaaaag caaatttagt tgtagattca acaaatcaat
    22561 taaagtttga atatatacaa gaaaagtata atgagtatat agttaggaga attatatgaa
    22621 atgtttattt agtaatgtag atgagtggaa gattatacaa gataagattg aaatcaaaga
    22681 aaatagatta gcagagtcca taatgagtat aggcaatgga tatatgggta tgagaggaaa
    22741 ctatgaggaa aattatagtg gagatacaca caaggggtct tatatagctg gagtatggtt
    22801 tccagacaaa actcgtgttg gttggtggaa aaatgggtat ccagaatact ttggtaaaat
    22861 tcctaattca gtcaactata taggtgtaag aattttcata gatgatgtag aattagattt
    22921 agcaaaatgt aaagtagaag atttttatag agaattagat atgaaaaatg gtattttaaa
    22981 tcgtaggttt attgtaaata taaatgataa aaaatttgaa gttagggttg ctaggttttt
    23041 aagtatatct gttaaggaac ttgcagtaat taaatacagt ataaaatcat taaattctaa
    23101 tactaaaata aaatttgtac catatttaga ttcaaatata aaaaatgaag attcaaacta
    23161 tgatgaaaag ttttggaatg gaatttcttc aagttcttta gaatataaag gtagtattct
    23221 ttctcgaaca aaggagaatg catttaatac accagtattc actgtgggtt caatgatgta
    23281 tattaagaca aatggtgatg tagaagctgt atctcatgag agtgattata attactgtga
    23341 aaattcgata acaatggatg ttttaaaaaa tgaggttgca agtatagaaa aatatgtatc
    23401 tataacttca actagagatt ataaggaaag tgagctatta agaaaatgtg aagacatttt
    23461 aaatagagaa ctatctaaaa gttatgatga tatattaaat gaacatacaa agttgtggaa
    23521 taaaagatgg gaaagtgcag atgtaaaaat aaatggagat aaaagtagcc aacaaggtat
    23581 aagatataat ttattccaac tattttcaac atattatgga gaagattcgc gattaaatat
    23641 aggtccaaaa ggatttactg gtgaaaagta tggaggagct acttattggg atacagaagc
    23701 gttttgtgtt ccagtatatc taggtgtagc agataaggag gtaactagaa atcttttaga
    23761 atataggtac aatcagttag aacaggcaaa ggataatgca aaaaaactag ggcttaaagg
    23821 tgctttatat ccaatggtaa catttgatgg agtagaatgt cataatgaat gggagataac
    23881 atttgaggaa atccaccgaa atggaagtat agtatatgca atatataact atacaaatta
    23941 tacaggtgac tataaatata taaaagaaaa aggaatagat gtaataatag aaatagctag
    24001 attttgggca agtagagttc atttgtctac aaaaaaagat ttgtatatga tacatggagt
    24061 aacaggtcca aacgagtatg aaaacaatat caataataat tggtatacta attatatagc
    24121 taaatggtgt ttagattatg ctgtagaaaa tatcttacga ttagagaaag agtgtaatga
    24181 atgtattgac agaaataatg tgactaggga agaagttgag ttttggaaaa taatatcaaa
    24241 taaaatgtat ctaccgtatg atgaggaact acaaataata attcaaaatg ataatttttt
    24301 agataaagaa tttgtagaag taaaggattt accaaaagaa aattttcctc ttaatcaaaa
    24361 ttggtcttgg gataagattc ttaggtcgtg ttttataaaa caagcagatg tattacaggg
    24421 aatttactat tttggaaata gatttactaa agaagaaaaa aagagaaatt ttgacttcta
    24481 tgaaaaatat actgtacatg aatcttcttt atcttctagt atttattcta ttattgcctc
    24541 agaaatagat aacctagaaa aggcttatga attatattca agaacagcta ggcttgattt
    24601 agataattac aataatgata caaatgatgg actgcacata acttcaatgt ctggttcatg
    24661 gctttccatt gtacatggat ttgcaggcat gagaacatgg aatgaaactc tatcttttga
    24721 ccctaagttg ccaaaagagt ggaaaaatta ttctttcaat ataaattata gagataatat
    24781 tattaatgta gatgtatgta gtgatttaat taaaatagaa aatttaaaag gtagaccaat
    24841 aaaaattatt gtatatggga aaaaatatat attagaaaaa tgtataaaaa ttgataaata
    24901 gatttaataa tattttt
//
LOCUS       DAEOTL010000053        24313 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEOTL010000053 DAEOTL010000000
VERSION     DAEOTL010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24313
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.053"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            109..300
                     /locus_tag="KRH82_002541"
     CDS             109..300
                     /locus_tag="KRH82_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBG8655814.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            455..1864
                     /locus_tag="KRH82_002542"
     CDS             455..1864
                     /locus_tag="KRH82_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8655815.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTAEDFSSLETALNNVVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQVIDLEDI"
     gene            1995..2684
                     /locus_tag="KRH82_002543"
     CDS             1995..2684
                     /locus_tag="KRH82_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBG8655816.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2687..3622
                     /locus_tag="KRH82_002544"
     CDS             2687..3622
                     /locus_tag="KRH82_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBG8655817.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3619..4512
                     /locus_tag="KRH82_002545"
     CDS             3619..4512
                     /locus_tag="KRH82_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBG8655818.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4590..5336
                     /locus_tag="KRH82_002546"
     CDS             4590..5336
                     /locus_tag="KRH82_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBG8655819.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAAYRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5337..6170
                     /gene="rsmI"
                     /locus_tag="KRH82_002547"
     CDS             5337..6170
                     /gene="rsmI"
                     /locus_tag="KRH82_002547"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBG8655820.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6193..6897
                     /locus_tag="KRH82_002548"
     CDS             6193..6897
                     /locus_tag="KRH82_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBG8655821.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7085..7513)
                     /locus_tag="KRH82_002549"
     CDS             complement(7085..7513)
                     /locus_tag="KRH82_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBG8655822.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7550..8980)
                     /locus_tag="KRH82_002550"
     CDS             complement(7550..8980)
                     /locus_tag="KRH82_002550"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBG8655823.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9112..9696
                     /locus_tag="KRH82_002551"
     CDS             9112..9696
                     /locus_tag="KRH82_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBG8655824.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9712..10233
                     /locus_tag="KRH82_002552"
     CDS             9712..10233
                     /locus_tag="KRH82_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HBG8655825.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10299..10545
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10629..12566
                     /gene="metG"
                     /locus_tag="KRH82_002553"
     CDS             10629..12566
                     /gene="metG"
                     /locus_tag="KRH82_002553"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBG8655826.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTNFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKDELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12596..13366
                     /locus_tag="KRH82_002554"
     CDS             12596..13366
                     /locus_tag="KRH82_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBG8655827.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELSKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13704..14135
                     /gene="phnG"
                     /locus_tag="KRH82_002555"
     CDS             13704..14135
                     /gene="phnG"
                     /locus_tag="KRH82_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBG8655828.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14150..14725
                     /gene="phnH"
                     /locus_tag="KRH82_002556"
     CDS             14150..14725
                     /gene="phnH"
                     /locus_tag="KRH82_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBG8655829.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSSINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14728..15813
                     /locus_tag="KRH82_002557"
     CDS             14728..15813
                     /locus_tag="KRH82_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBG8655830.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15833..16702
                     /locus_tag="KRH82_002558"
     CDS             15833..16702
                     /locus_tag="KRH82_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBG8655831.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16695..17561
                     /locus_tag="KRH82_002559"
     CDS             16695..17561
                     /locus_tag="KRH82_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655832.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYIFHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17602..18315
                     /locus_tag="KRH82_002560"
     CDS             17602..18315
                     /locus_tag="KRH82_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8655833.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMAKGTISESGVA"
     gene            18316..19485
                     /locus_tag="KRH82_002561"
     CDS             18316..19485
                     /locus_tag="KRH82_002561"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBG8655834.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPSNGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19489..20325
                     /locus_tag="KRH82_002562"
     CDS             19489..20325
                     /locus_tag="KRH82_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBG8655835.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSSLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20326..21321
                     /locus_tag="KRH82_002563"
     CDS             20326..21321
                     /locus_tag="KRH82_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8655836.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21339..23027
                     /locus_tag="KRH82_002564"
     CDS             21339..23027
                     /locus_tag="KRH82_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBG8655837.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23039..24106
                     /locus_tag="KRH82_002565"
     CDS             23039..24106
                     /locus_tag="KRH82_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8655838.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
BASE COUNT         9706 a         2716 c         4339 g         7552 t
ORIGIN      
        1 ttttttgtca aaaaaaacaa aaaatacgta tttctttttt catttcggga aaactaaaca
       61 caggaattat ggactttata aaaatttaat tcttgaggag tgatataagt gaaaaaagtt
      121 gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat tctaggtaca
      181 gacttaatag gtagtatctt tggtggaaca tatgaaatgg taagtagaat aatatacttc
      241 attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga tagagaataa
      301 tttatgcttt tatgttaaat acctcattct aaatgtttag aatgaggtat ttaattttat
      361 aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa gttttaaaaa
      421 gaagtattat gtaaaaaagg agtactatta atatatgttt attattaatg aattaaataa
      481 gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaaagg gacaggttta
      541 taaaaagtta ggatataaag atatactaaa aaatttgtat aaaatggata caactgagat
      601 attaggaaca gataatttac actttccgga aggaattata aaaaattcac aaaaaaaagc
      661 atcaagagta tttaaaagtg attatacttg ctatttagta aatggtagta gctgtggaat
      721 acaatctgca ataatgtcag tatgtagtcc taaaagtaaa ataataacaa atagagactg
      781 tcatcagtct gttataaatg gatgtatttt aggagatata gatatagagt atgtgccttg
      841 tgagataagt gaagagacaa atatcttaaa agggatatct ataagtaatg tgattgatat
      901 aatagataaa aacttggatg caaaagcagt actgcttact tatcctacat attatggaat
      961 gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaagatgg tagtgatagt
     1021 agatgaagca catggtgcgc atttagggct tagcgagagg cttcctaaaa cagctcttga
     1081 gcaaggcgca gatatagttg tacagagtac acataaaact cttccagcat ttacacaatc
     1141 gtcaatgata catatacagg gagaccgagt tgatatagat aaaatattga acatgttaag
     1201 aattacagaa tcttcaagcc cttcatattt attattatct tctctggaat tagcagtaga
     1261 tatatatgaa aataaaggaa aagaattaat ggaagagctt ttaaataata ttataacttt
     1321 caaaaataaa gttgattcaa atattaatat atacgacaca aatgataaaa caaaaatatt
     1381 tatatcatct aaaaacatgg gtttaacagg ttatgaacta gaaaatattt tgagaaataa
     1441 atataacata caagtggagt tatctaatta ttatggagtt cttttaatat gtacaatagg
     1501 aaatactgct gaggatttct ctagtttaga aacagcatta aacaatgttg taaaggaaga
     1561 ctttaaattt gaaaagttag aaaataaaaa ataccctgtt gttattccaa agaaaatatt
     1621 aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg acagcatagg
     1681 taaagtttgt ggtgaatgta tagttccata cccacctgga ataagtgtaa tatctcctgg
     1741 tgaagtaata agtaaagaaa taatagacta tctaatgttt tgtcattcta aaggcatgat
     1801 tgtgagtgga ttgaaagatg tagatttaaa ttttatacaa gtaatagatt tagaagacat
     1861 ttaaaaatta tgatataaaa gtagatagaa gtagatagtt taaaattgtg aagagaaata
     1921 aatagactgc ttatatagag ctatctaata aaagtactaa aaaagtaaaa agtgtttgta
     1981 tggaggatat gaaaatgaaa ggtaagttaa taattataga gagtggttca gatgcaagtg
     2041 gaaaggctac tcaaacagaa atattatatg aaagattaaa aaaagaaggc tatatgatta
     2101 aaaaggtaga atatccaaat tatgaatctc catcatctgc cttggtgaaa atgtacctaa
     2161 aaggagactt tggtaaaaat gcatcagatg tagacccata tatagcatca acttttttta
     2221 cagctgatag gtatgcatca tttaaaaccg attgggagga gttttacaat gaaggtggaa
     2281 taattatcgc agatagatat acaacctcta atatggtaca tcaggcctct aaaatggata
     2341 tttgtgatag agaagagtat ttaaattggt tagctgatta tgaatttaat ttatttaaga
     2401 taccacaacc tgattgtgtt atatttttag atgtgcctat tgaatttagt aaaaagctta
     2461 tggagaatag aaaaaataaa attacagggg aagaaaaaaa ggatattcat gaaagtgaca
     2521 tagagtattt agagaaatct tacaacaatg ctttatatat agcagataaa tatgattgga
     2581 aaaaaataaa ttgtgtttta gataacaaat taagaagtat tgaaagtata cataatgaaa
     2641 tttataaaat agttcttgat tcaataaaac ctatggagag ataaatatgt attttgaaaa
     2701 tattataggg caagattttg caaagaaata tttaacaaat tctataaaga aaaataaact
     2761 taataatgcg tatatgtttg aaggaatgga tggaatagga aaaaagaaat ttgcagatga
     2821 attatcaaaa ctattacttg attatgaaaa tctcgaaaat agtccagact atgtactcat
     2881 aaaaccagat ggaaatagta taaaaatagc tcaaatcaga aatttacaat cagatatagt
     2941 aataagacct cataaagact ataaaatata tataatcaat aatgctgaaa aaatgactgt
     3001 ggaagctcaa aatgcacttt taaagacgtt agaggaacct ccaaactatg ctataataat
     3061 cttagtcaca aacaacaagg aatctttatt agaaactata aaatctagat gtgatataat
     3121 aaagttctca cctataccaa ttgaagactt aaaacgttat ttgataaata caggtataga
     3181 agaagaaaga gctcaattat tggctatttt ttcgagagga agtattgaga atgctctaaa
     3241 tctatctcag tcttctgagt tttcaatgat gagagaagat atacaacagt atattcagat
     3301 aatgttagat aaaaacatag tggagatttt aaatatacca aataatatgg aaaaatatag
     3361 aggtaagatt atagctttat tagatatgat gataaactat tttcgagata tcatcctatt
     3421 aaaagaaaat gtaaacaaga acatgttaat aaatgtagat aagctagttt tcattcaaaa
     3481 tatgagtgga aaaattagtt attctcaatt gtccaagatt attgatataa tagaagatgc
     3541 aaagagtaaa ataaaaagca attgcaattt caatataagc atacaagtta tgtctttaaa
     3601 tatatacgag gtgattaaat gataaagata gtaggtataa ggtttaaaag tgctgggaaa
     3661 atatattatt ttgaccctgt tgattttaat atagagcaag atatggatgt agttgtagaa
     3721 actgcaagag gcttggagta tgggaaagta gtcgttggtc caaaagatat ggatgaaagc
     3781 gaattagttt ctcctttgaa gccaattata agaatagcta cagaagaaga taaaaaagta
     3841 tatctagaaa ataaggaaaa ggcaaaagaa acttttgagt tgtgccaaca aaaaataaaa
     3901 gaacatgagt taacaatgtt tttaatagat tgtgagtata catttgatag gaataagttg
     3961 attttttact ttacagcaga aggaagaata gattttagag aattggtaaa agacttagct
     4021 gctatattta aaactagaat agaacttaga caaataggtg tcagagatga agctaaatct
     4081 ataggaggtc tagggccttg tggtagaaaa ctttgttgtt catcttggtt aggtgatttt
     4141 caaccagttt caataaaaat ggcaaaagac caaagtctat ctctaaatcc aacaaaaata
     4201 tctggaatat gtgggagatt attctgttgc ttaaaatatg agcatgatgt atatagtgaa
     4261 gcaatagaaa aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg aaaaggaaaa
     4321 gttgtagaag tgaatccttt attagaacaa attaaagtgg aatttcaaga caagacagta
     4381 aagatatata caagagaaga tataaaaata cttagagagc ctaaaaaatg tgatggctgt
     4441 ggtggtaaat gtaaggataa tgatggatta gatgaagcca cactaagaga gctaaagaaa
     4501 ttagaagatt aaatttaagg tagggctttt cctacctttt ttaaagcaat taatgcttaa
     4561 agttattaat atttgaggag aatttatata tgcaattaaa agattcagaa agaatagatg
     4621 atttacaatt aaaaggcctt aaaattatac aagatactaa tggtttttgt tttggtatag
     4681 atgcagtttt attagccaat tttactaaaa taaaaaaaga tgccaaagta gtagatttgg
     4741 gtactggaac tggaattata cctattttga tagctggaaa aagtgaagct aaaaaaatta
     4801 ttggcgtgga aatacaagaa gatgtatatg aaatggcaac tcgttctata aaattaaatg
     4861 gattagaaga aagagttgag attataaatg aagatataaa atacatagac aaagtcttag
     4921 acataaatgg ttaccatgta gtcacatcaa atcctccata tatgcatatt gatggaataa
     4981 aaaatccaaa tgataaaaaa gcaatatcaa gacatgaagt aaggtgcaat ttggaagatg
     5041 taattagagc tgcatacaga ttggttatgc ctagaggaaa attcttcatg atacatagac
     5101 caacaagatt ggttgatata ataactttag ggagaaaata taaattagaa ccaaaggtta
     5161 ttcaatttgt gcatccaaga cctcaaaaag caccgaactt agttttggtt caatttgtaa
     5221 aagatggaag gccagagctt aaaatattgg acccattgta tgtttatgga gaagatggga
     5281 attatacaaa agaattaaaa gcaatatata ataataaaga tataggagag ttgtaaatga
     5341 gcgggaaatt gtacatatgt ccaacaccaa taggaaacct agaagatata acatatagaa
     5401 ctttaagaat attaaaagaa gtagacttga ttgcagcaga agatacaaga catagtataa
     5461 aacttttaaa tcattttgaa atctcaaaac cactaactag ttatcatgaa cataataagg
     5521 attcaaaggg agattatttg ataaataaac taattgatgg tgaaaatata gctctgataa
     5581 gtgatgcagg tatgcctggt atatctgacc caggagaaga gataataaaa caagctatac
     5641 aaaataacat agagatagaa gtattgccag gtgcaacagc ctttgtaacg gctttagttg
     5701 gctctggtat ggacacacat agatttgttt ttgagggctt tttagataga gataaaaaag
     5761 ttaggaaagc acaattggaa gaattaaagg aagaaagtag aactataatt ttctatgaat
     5821 caccacatag attgaaggat acactaaaag atatgcttaa aattcttggt aataggaata
     5881 tttctataaa tagagaactt acaaaaaaat atcaagaaat aataagagaa aatatagaaa
     5941 ctaccataaa aatatttgag gaaaaagaag taagaggaga gtttgtatta atagtagagg
     6001 gttttcatgg tgagaagtca aagaaagaaa attatgatgg gcttacagat agggaatatg
     6061 ttttaaaact aattgaaagt ggtatgaaca aaaaagatgc aataaaaata gtttgtaaag
     6121 atagaaagtt aaagaaagat gtggtttata aacaagtttt agatttataa agcctgaatc
     6181 tgaggtgatt ttatggaaat agggaaaatt ataatagaga gtttaaagag ggaagataca
     6241 cataaaatat ttatagaatt agataataag catgaattag aaaaaataat tcctaaaata
     6301 agctgtatga agtctgtagg tgaatgtaaa tatcatgtag taaattgttt tgaacattct
     6361 ataaatgcat taaaagaatt agaaatagta ttaaatgata aggatttttt tccaatacat
     6421 ctaagaaaac atgtgtcaaa ctatttaaac acatatattg aagaaggaat aaataagtta
     6481 catgtattaa agctgggaac atttttacat gatataggta agcctgacag tatgacctta
     6541 gatgaaaccg gaagagttca tttcacaaat catgaaaaaa taggtgctca aataattgac
     6601 aatatgggaa taaagttaga gttatcaaca gagacatata gacttataag taaatatgta
     6661 agatatcata tgatactttt gtctctatat aagaaaaatg atttgagtag gaaagaatta
     6721 attaatgtat ttaacttagt agatgaggac actataggtg taataatgct tgggtatgca
     6781 gatatagtgt ctacagtaaa attattgggt aagagtggag aagtcagtgt gttaaagaca
     6841 tatatggaat atattttaac aaattacttg tataagagta attatacaca tgtataaatt
     6901 tagttaatat aattgagttt tagatgatta attaaagttt gaaatatacg gatttcaaaa
     6961 acataaaaga agttgtcttt gttgtaaaat tatgaaagac aacttttttt atatcaaaaa
     7021 ttgaaatttt attaaggata cttaatggtc tattaattaa taaaccatta gtatttaatt
     7081 tatattacaa tattgatttt gcttgtattg gcgttgatag tataacagag gtcttagtag
     7141 aaccaatttt ctttatagta tcaatcacat tttctagctc gtacatatct tttacaatta
     7201 cttttaaaag taagcaatca tcacctgtta tatggtgaca ttctacaatc ctagggtcct
     7261 ttgcagctga ctcaataaat tctgtatatc cattgcttgg aagagaaata tgaataaatg
     7321 cctttataac tctgcctaat gaatctgggt tgacaatagc tttatatcct tctataacac
     7381 cagactcttc taatcttttg actctttctg aaactgcagg agaagttaaa ccaactattt
     7441 ttcctaagtc cttcatagaa attctcccat catcctgtaa aatttctatg attctgtaat
     7501 ctgtaacatc cataaataaa cagtccccct taaataaaaa taattaatgc tataaaactt
     7561 ttttagaatc tatcatttgt gtttttaaat accaaagatt tctagataaa tcaaccttat
     7621 aaatgtgtgg ttttgaaagt cttttgtatt gttcccagat agtacttaat tcatattgta
     7681 catgattttt tatttcaaga acagcttttt tattatattt gcatctgcct tttatataca
     7741 atggtttaag aagctcttta actttgtaat ttgtaaatac ctttgttttc catgtataag
     7801 taggatggaa gatttctaaa ggtttagact catctataac ttcatcatgt aacataatca
     7861 aatctgcctc tgccttattg tcttcgttat atattcttat aactttcttg taaccaggat
     7921 tatttatttt ttctggattc tcagaaatct ttatcttagg ttcaagaact cctttttcac
     7981 aagatgcagc taatttataa actcctccaa gagaaggtga atcgaaagat gtaatgagct
     8041 ttgtacctac tccccatgaa tttatagtag ctccttctgc tttaagtgat gttatggtat
     8101 attcgtctag gtcattagat gcagtgatgc tgatatctga aaagccagcg ttatctaatt
     8161 gttttttagc ttctttagat aaataagcta aatctccaga gtcaagtctt atacccatag
     8221 gtttgtatcc tttttcagaa atatttttga atacttttat tgcattagga actccactgt
     8281 ttaatacatc ataagtatct acaagtagta ggcatttatc tggataaaca tcagcatatg
     8341 cttggaatgc ttcaagttca ttatcaaatt tttgtaccca actgtgagct tgtgtaccaa
     8401 ttataggtat atcaaacatt ttccctgcta gtacgtttgc agttccagca caaccaccaa
     8461 ctacagcagc cctagcccca tatatccctg catctggacc ttgtgcacga cgtaatccaa
     8521 attcaaatac agggtctcct tgagctgcaa agcaaactct agaggcttta gtagcaataa
     8581 gagactgaaa attaactatt gttaacaatg ctgtttcaat aagttgagct tgatataaag
     8641 gtgccttaac agtaattaat ggctcattag ggaacatgat agttccttcc tcaacagcat
     8701 atatatctcc tgtgaattta aattctttta aaaattttaa gaacttgtca gaaaataaat
     8761 ttaagttttt taagtactct aaatcttcat ctgaaaaatg aagattatct atgtattcaa
     8821 caacctgatc aataccacaa actatagtat accctccatc acaagcgttt tttctaaaaa
     8881 acatatcaaa tacaacaatg tcttcatgaa tattcttttc aaaatagcca tttaacatag
     8941 taagctgata taaatcagta agaagtgtta gatttctcat tatttctctc cttaattatt
     9001 attaaatatt aaaaattgta aaaactccca cacttatact aaaacataat atagtacaac
     9061 tttcaagtat aaagtattac ctaactatca taaaattatt taaagaggag gatgattata
     9121 ataggaaaaa tatggtttta tatggtatcg ataggaataa taggaagctt gatttctaaa
     9181 aatatgggtg aattaaataa agttatatta agtgaaacat caaaaggtat agagtttgca
     9241 ataagtctag ctggtatcat ggcactctgg atggggataa tgaatatcgc aaaagaatca
     9301 ggtttaattg aaaagatagg tcaaaaacta aatcctataa tgagaagatt atttccttct
     9361 attccaaaag gtcataaagc aatgtcttat atagttatga atattgcttt aaatatgttg
     9421 ggtgctggaa atggtgcaac agcatttggt ttaaaagcaa tgagtgagct tcaaactttg
     9481 aataacaaga aagatacagc cactaatgat atgattatgt ttatggtaat caatatatca
     9541 tctatacaaa taattccatt taccataatc aaactaagga tggatatggg ggctcaaaat
     9601 ccaagtgaaa taatttttac gactttattt gcaaccataa tatctacagc agtagcaata
     9661 ataacatgta aattttttca aagaagatat agataaaggg gatgtagata catggagata
     9721 ttttcaaact tacttatacc aataataatt ctgtacatag taatttatgg taaatataaa
     9781 aaaatagatg tgtatgatag ttttgtaaaa ggagcaattg atggattaaa agctgcatgg
     9841 gatatcctac catatataat aggtatattt ttggcaatag gaatattcaa aactggtaaa
     9901 ggtcttgata tgttagaatg gctatttaca ccaatagcaa atatgatgag tataccaaaa
     9961 gaattaatag gtctaataag tgtaaaacct ttatctggaa gtggtgcttt agggatgtac
    10021 agtgaacttg caaatagagt tggaatagga agtttagtag aaaaaatggg tgctacgatt
    10081 gtaggttctt ctgagactat tttttacaca atggcaatat actatggaag tctgaagata
    10141 aaaaatacta gacatacatt atcatgtgct atgattagcc atgttgcagg tgtcatagca
    10201 gctgttttta tttgctatgt aatatttgta taatttgttg acaatatggg aaaaatttta
    10261 taatatagtg attatataga aacaaatagt aatacaaatt acaagctatg aaaagaagag
    10321 taaataaagg ttttttctat cagagaacta ggttaggtga aagctagtgt caaaagcttt
    10381 attgaagatg gtcttggagc tttttatctg agcaagtgtg ctagggtaaa acggttggac
    10441 acgttatagt ctactaaggt atctataaaa tgtttctaca tttcatgtga aacataacta
    10501 ttatagatga attagggtgg taccgtgaat aatctcgccc ctatgttaac tcataggagg
    10561 cgatttttta ttatttaaat gaaagaatca tatgattacg aacgataaaa aattaggagg
    10621 taaataacat gagcaaaccg agtttttatg taacaacacc aatatactat ccaagtggag
    10681 gattacacat aggacatact tattcaacag tagctgcaga tacaatagct agattcaagc
    10741 gtttctgtgg atatgatgta aagttcttaa caggaacaga tgagcatggt gaaaaaattc
    10801 aaaagaaagc catagaacaa ggaatgtcag agatagagta tcttgatgga atgataaaag
    10861 atataaaggc cttatggaat actatggata tatcttatga tgattttata agaactacag
    10921 aaaaaagaca tacagacata atacaaaaga tatttactaa actatatgag caaggtgata
    10981 tatataaagg tgaatatgaa ggtagatact gtactccttg tgagagtttc tggacagaat
    11041 ctcaattact agaaggaaat aaatgccctg actgtggaag agaaacatat ttagtaaaag
    11101 aagaatctta tttctttaga ttatctaaat atgaagacag attaaaagag ttatttaaag
    11161 atgatagttt ctgttttcct gctgctagaa aaaatgaaat ggtggcaaac tttttagaca
    11221 aaggattaga agatttaagc gtaactagaa cgacttttga ctggggtata aaagttcctt
    11281 ttgatgaaaa acatgtaatt tatgtgtggg tagatgcttt atgtaactat ataacagcat
    11341 taggttatat gactgataat gatgaagaat ttaaaaaata ttggcctgcc aatgttcaaa
    11401 tagtaggtaa agaaatagtg agattccata caataatatg gccagcgctt ttaatggctt
    11461 taggtctaga agttccaaaa caagtatttg gacatggatg gatactattt gctgatgata
    11521 aaatgagtaa atcaaagggt aatgtggttt atccagaacc tataatagaa agatatggaa
    11581 tagacacact taagtacttc ttattaagag agtttgcatt tgggcaagat ggaagttata
    11641 ctcatagaaa ttttgtaacg agaataaatt atgatttagc aaatgattta ggaaacttaa
    11701 taagtagaac tgtagctatg gttgaaaaat acaataatgg tataatacca acagcaaaag
    11761 tttcaactaa ttttgatgct gacttaaaag aacaagctgt ttcaactaga gaaaactttg
    11821 aagctgaaat ggataaaatg caattccatg aagcattaga gagtgtatgg aaattagtta
    11881 gaagaactaa caaatatata gatgaaacta tgccttgggc actagctaaa gatgaaacga
    11941 agaaagatga attagacaca gttttatata atttatgtga atctataaga ataatcgcaa
    12001 cactaataaa tcctataatg aatgagactg ctaataaaat atatgaacat ataggaataa
    12061 aaggtcaaga tgatataact acatgggaaa gtacaaaaac atttggtctt attggagaaa
    12121 atgtaaaagt atttaaaggt gaacctttat tcccaagatt agatgtagaa aaagagatag
    12181 aagaattaac taaaatgttc tctgggaaac ctccagtaga agaaaaacct ttagagcata
    12241 aagaagaaat tactattgat gatttagaca aaatagagct tagagtaggg aaaataataa
    12301 gctgtgaaaa acatccaaaa gcaaataaat tattagtatc acaagttaag attggaccag
    12361 aaacaagaca aatagtatca ggaatagctg aatactataa gccagaggat ttagtaggaa
    12421 aagaggttac agtggtatgt aacttaaaac cagttaaatt aagaggtgta gaatctcaag
    12481 gtatgatatt agcagcaggt gatgatggag acccatatgt tttaccattt acacaagggg
    12541 ctaaagatgg atgcgaggtt cgttagtagg taattaaata gtaaggagat taaagatgtt
    12601 atttgactca catgcacatt taaatgatga aagttttgat gaagatagag atgaacttat
    12661 tggttcatta aaagataaag gtgtagattt ggttgtaaat ccaggagcag atatagagac
    12721 gtcgataaca gcaattgaac tttcgaaaaa atacgacttt atatattcag cagttggggt
    12781 acatccacat gatgtatcaa aactagatga tacagcaata gaaactctaa gaaaacttgc
    12841 aactgagaat gaaaaagttg tagctattgg agagattgga ttagattatt attatgatta
    12901 ttctccaaga gaagaacaaa aagagtggtt taagaagcaa attgaattag ctaatgagct
    12961 aaaacttcca ataataatac atgatagaga tgcacatgga gatacttttg agataataaa
    13021 gaatactaaa aatcctgaaa taggatgtgt acttcattgt tatagtggga atgtagagtt
    13081 agctagagaa tatgttaaga tgggttgtta tatatcaatt ccaggcacgg ttacttttaa
    13141 gaataataaa aaaactagag aagtagtaag agaaatacct ctagaaagat tattcataga
    13201 gactgattca ccatatatgt caccagagcc acatagagga aagagaaaca atccttccca
    13261 agtatctttt gttgctgata agatagccca ggaaaaaggg atatcttatg aagaagtatg
    13321 tagagttaca aaagaaaatg caaagaaatt ttttaatata aaatagacaa attaaatctt
    13381 ataatgatat atataataag tcattataag tataggatga gagtgcctca aaatgagttt
    13441 tttagttcat gaggcactct tttttttatg aaatcaaata tattttcatc atttcaacaa
    13501 tgaaaaagaa gtttatcata ttttgagata gtttgttttt atttatttaa ttcatatttt
    13561 aaaatatatt ttcttaacat tgttaaaaaa gaatttacaa gatattcatt agaattaact
    13621 caactctaat attcacttaa cttaagttgt ttattatatt attaaagaga agtaaacgaa
    13681 aggtagatta aggaggttga attttgtata cagttgatag tactaagata ttgataaata
    13741 tgaacttaga gaaactagaa aagatatact caatgataaa agatacatca agtatttcta
    13801 taattaaaga acctaacttg gctacagtaa tggtaagagc taatgaaagt gtaaaaaaca
    13861 caacatttaa tttaggagag atattagtta ctgaatgtag tgtaaaggta gatgaaagct
    13921 tgggttacgg aatagtttca gaaaacaata ataagaaagc catttattta gcagttatag
    13981 atgcagtttt acatagcaat aacagtaaat ttgatgagtt aaagaattac ataaataaaa
    14041 gtgtatatga agagaactta aggtatgaac aagagattat tgatgaattt agcttgatta
    14101 ataaaacgaa agttcaattc aatgctatgg attaaatagg aggagaatca tggtaaatta
    14161 tacacaagaa atatatagaa agatgctaga tagtgcttca tttcctggga aattaaataa
    14221 tatagataat ataaatatag aaaataatac aaaactattg aatggagcaa ttggtatagc
    14281 aatcacttta ttagaccaag aagttacctt ctatatagaa aattatactc aaaaagatat
    14341 aaaaaatata agagcactta caatgtcaaa tcaaatagat tatagaaaat cagattatat
    14401 atttttagat attaattcag aagtggatat attacagatt aaaataggtt cttttgaata
    14461 tcctgatgaa agtgcaacta tagtacatca agtaaatgat ttatcaacgt actctcaaac
    14521 taagtatata aagcttgatt tgagtggtcc tggtataaaa tctaaaaata gtatatatat
    14581 aaatggaatt agagaagaat ttatagaaag attatctagc ataaataaag attatccaat
    14641 aggaatagat ttgattttag tagataaaaa aggagaaatt gcatttatac caaggtcatc
    14701 aaaattaagt tgggaggtat tatagaaatg gcttatgtag cagttaaagg tggagaagaa
    14761 gccatattac aggctaaaaa tatacttgag ttttataggg taaaaggaga tagcttgcct
    14821 atagatgtaa agcagattga ggaacaaatg tcttatgctg tagacaaagt aatgtctgaa
    14881 ggaagtttat acaacaagga actatcagca ttggctataa aacaagctca aggtgatata
    14941 ttagaagcct ctttctatgt aagagcttta aggtcaacaa tgcctagaat tacatattca
    15001 gaacccataa atacagaaga aatgagaata aaaagaagaa tatcagctac ttttaaagat
    15061 ataccaggag gtcagtatct tggggcaact agagattatg aaaatagaat attgaatgta
    15121 gaattattag aagaagatga aaaaaagaat agagatttta gagatagttt tataaatgaa
    15181 ttagaaacag tagatgaaat ccctgaattt acaaaaatat ctaatatatt tagaaaagaa
    15241 aatttattac aagaagaagt ttgtgaaaac aaattggaag aagttattga tgatattaca
    15301 agaaatagtt taagatttcc agtttctagg tcagcaaagt tacaggcatt aactagaggt
    15361 gaaagtggag tagtgtcagg ttttgcttat gctattgtaa gaggttttgg tgatgaacat
    15421 ccatatataa gtgaacttag aactggtaat gtatttataa aagtaaaaca tcccatctat
    15481 gaagatgaag aaataataat aggggatatg ctggttactg aatgtgaaat agtttcaaaa
    15541 gcatcacaaa ataagactga aaattctaaa actaattcgg aagataaaaa taagatgtct
    15601 ttaggatatg gtctttgtat ggggaataat gagaataagg ctatatctat ggccatacta
    15661 gacaaatctt tggagccaaa tagtgaaaaa ctagcacaag atgaagaatt tgtattgctt
    15721 catatagatg gaatagattc attaggattt atatctcact ttaagcttcc tcactatgta
    15781 gattttaaag cggatgtaga aagaataaaa tagtttgtgg aggtaagttt aggtgatata
    15841 taactatggt tttttagacg aaaacacaaa aaaagaaata agaagaaaga tattaaaagc
    15901 aatatcaata cctggttatc aagttccctt tggttcaaga gagttgccta tagctaaggg
    15961 atggggtact ggaggtttac aattaacact atcattaatt ggtaaaaatg atgtagtaaa
    16021 agtaattgac caaggaagtg atgattctac aaatgcttgt aatataagga gctttattgc
    16081 aagtgtaagt aatgtagaaa ccacaaaaga tacattagaa gctacattga ttcaaacgag
    16141 acatagaata ccagaagaaa aacttaaatc taatcaaata ctaatatttc aagtaccaat
    16201 accagaaacc cttagaatag tagaacctag tgaagtagaa acaagaagaa tgcattcaga
    16261 agaagattat agtaggatgt gggtatatct ttatgaagat atagttagat ttaatgatat
    16321 atctatagca gttgaatatc catgtaaagt aaatgataga tatttaatga atccatcacc
    16381 tatacctaga tttgatataa aaaaattaaa tatgtcagac aatttattct tgtttggtgc
    16441 aggtagagaa aaaagaattt atgctattcc tccatataca aaggtagaac ctttagagtt
    16501 tgaggattat aagtttgaag aggaaaagtt tgaaggaaaa tactgtagtt tatgtaacag
    16561 tacaaataca tttttagatg aagtatatga cagtgacact aatgaaaagt actatagttg
    16621 ctcagataca agttattgtg aaaaagttag attaaaaaat aacagtatag atgtgacaat
    16681 aggaggtact tggaatgagt aaaataaatg actctaaaag attagaaaat atagacaagc
    16741 aagtattaat aggaagaaat atcaatctta tttatggaga tgggtgtgaa aagtgttttg
    16801 aaagcacagg atatgaaagc aataatatat gtaagtattg tggttctata gttgcatgta
    16861 ataatgtaaa tttagaactt tatgaaggag aagtccttgg aattgtaggt gaatctggtt
    16921 caggaaaaag cactttatta aaaatactgt ttttccaaga acatgcaaat agtggagaag
    16981 tatatatatt ccattacaat aaagacacaa atatactaga gctttcagac caaaaaaaga
    17041 gatacataaa gaatcatttt atgggtattg tgtatcaaaa tccccacctt ggtttaaatt
    17101 tagactttag tagtggtggt aatatagcag aaaaattatt gatggcaaat ttatataatg
    17161 ttgaaaaaat aagagataga ggcaaagaac ttttaataaa aactaatata cctgtagaaa
    17221 gaatagacca taaaccaaaa tactttagtg ggggaatgca acaacgagtt caaatagcaa
    17281 aagctctttc aaataaccct ccaatattgc tattagatga ggttacaaca ggtttagatg
    17341 tttctgtgca agcggaagta ttggatttaa taagagaaat ccaaagagaa cttaagattt
    17401 ctatgatagt tgtatcccat gactttgatg ttataaagat gcttgctgat aggacaattg
    17461 taatgaaaaa tggaagtgtg attgagtctg gtcttacaga ccaaataatg gaggacccac
    17521 aacacccata tactcagcaa cttataaatt cattgctata aatatcgttt gtaaataagc
    17581 aaaatggggg tttttaataa aatgaaagaa actatacttg aagtaaataa ttttagtaaa
    17641 gactttgagt tacatgcatt gaacaagact ataacggcat gtagtaatat aagttttgaa
    17701 gtttcaaaag gtgagttttt aggaataata ggtaaatctg gagcaggtaa gtctaccata
    17761 ttaaaaagta tctataaaac atatatacca acaactggag aaataatttt taattcagaa
    17821 atatatggta atgtagacct ggctaaaatt ggagaccgag aaatgataaa tcttagaaag
    17881 aaagaaatag gatatgtatc acagttttta aagacacttc cacgaataac tgcaattgaa
    17941 ctggtagtac attctttaat tgagagtggg tttgaaaaag attgttcgta tgatatggca
    18001 aaagatatac ttaaccaatt tgaaataaag gaaaatttat gggatgcgta tccaaataat
    18061 ttttctggtg gagaaaaatt aagattaaat ttagctcaag ctatggttaa aaagcctaga
    18121 cttttgttac ttgatgaacc aactgcatca cttgataatc aatctaaaat atatgtaaaa
    18181 gaaaaaatgt tggagcttaa aagtcaagga actacaatga taggaatttt tcatgatata
    18241 gagtttatgg aaactgttat agataagacc tttactatgg caaaagggac tataagtgaa
    18301 agtggggtag cctagatgat aaaactaatt cataatgcaa atattgtatt agaagatatg
    18361 attttagaaa atggtcattt aatcatagag ggagatacaa taaaaaaagt atcaaatgat
    18421 aagattgatt acgcatttga ctttaatgag atagatgaaa taatagatgc aaaaaactta
    18481 tatgtaatac ctggtattat agatattcac agtgatgcca ttgaaaagga aatagagcca
    18541 agaccaagta cattattacc atttaatatg gcattttatg aactagataa aaaactacct
    18601 tcaaatggaa taactacagt ttatcattct atatctttag gggatggagt aggagttaga
    18661 agtattgata actctttaaa gatgattaaa aatattgatt catataaaaa tatagatagt
    18721 aagagcataa atcataaagt tcatttaaga tatgaagtgt tgtattatga aggtttagaa
    18781 aaggttttag aactattaga tgaaaataaa atagactact tatcaataat ggaccattct
    18841 ccaggacaag gtcagtatac aaatccaaca ttttataaag agtatgctac taaagtgtgg
    18901 ggagttacag aaaattatgt agatacatgg ttagatgatt tagtaaatct gcatgataat
    18961 ttagattgga ataaaatagc taatattata ggtatagcca aaactaaaaa tataaatgtt
    19021 gcatcacatg atgatgatac attagaaaaa atggatttca taaaaaatat aggcataaat
    19081 gtatctgaat ttcctataac tcttgaagtt gcaaaacatt caaagaaatt gggtgttcta
    19141 acttgtttag gtgcaccgaa tattgtaaga ggtaaatctc ataataacaa tttaaaagca
    19201 atggatgcta tattggaaga ttgttgtgac attgtgtgtt cggattatct tccatcagct
    19261 atgataaagt ctatgtgtat agttgcagaa agaataaata atttaaataa agcagtcagt
    19321 ttatttacct caaatcctgc taaagcagtt ggtatatatg atgaaagagg tagtataaaa
    19381 gaaaataaaa aagcagattt agttttagta gatattgata gtgaatatcc aaaggttgta
    19441 aatactattg taaatggaaa aacagtttat aaaagggagg tataaagatt gctaacagag
    19501 ttacattgtc atacaagtat atcagataat aattttacta ctgaagaaat aataaaaaaa
    19561 gcagcagaaa agaatataaa tatcttagca ataacaaatc atgacacatt atctggattg
    19621 gatgaagctc ttgtgcttgg agagcattat ggaataacaa taataccagg tatagaaatt
    19681 tcagcatatg attataaaaa tagaaaaaga gttcatattc ttggatataa catagattta
    19741 aacagtcaag aaataaaaaa tttgtgcaat ccaatggtat gtgacagaca taaagcatct
    19801 gttaagatgg taaataaaat tatagattta ggatacaaaa tatctttgga agatgtaaag
    19861 aaatattcat caaagactgg aatatttaaa caacatataa tgaaagctct tatagataaa
    19921 gggtatacag ataatatata ttcaagtcta tataaagaat tgtttcatag aggaaacggc
    19981 aaggtatatg tatctttaaa atatgtggat tacagagatg caataaaagc tataaaaaat
    20041 tctggtggaa tttgtgtgct agctcaccca ggtcaaatgg ataattttag cgctattgaa
    20101 gagatggtaa aagtaggatt agatggaata gaagtatatc atccatctca caacaaagaa
    20161 ctagaaaaag agtcgctttc ttatgctaag aagtataatc tagtggtcac aggaggctca
    20221 gattaccacg gattttattc tcaacataat tatgaacttg gaagcaagag cttaaataaa
    20281 gaagatttat ttaagtttag gttagcttta ggaggggtat tataaatgtc ttttttacaa
    20341 gtaaaaaatg taggtaaaag ttatggacaa gttaaggtgt taaaagacat atctattgat
    20401 attgaaaaag gagagtttat ttgtttacta ggtccaagtg gttgtggaaa gagtacacta
    20461 cttagaataa ttgcagggct tgaggataaa catggtggaa aaataataat aaatgataag
    20521 gatatgacta attcaccacc tgaaagtaga aattttggta tagtttttca atcatatgca
    20581 ttatttccaa atatgaatgt ttacaaaaac atagcctttg gactagaaaa taaaaacata
    20641 agtaaatcta atattgataa aaaagttaaa gaagttctag aagttgtaga attaagtgga
    20701 tatgagaaaa aatatccatc acaattatca ggtggacaac aacaaagggt tgcattagct
    20761 cgtgcgattg ctttagagcc agacttttta cttcttgatg aacctttatc tgcattagat
    20821 gcaaaagtaa gacttaaact tagggagcag attagaagtt tacatagaaa actaggcatt
    20881 acaactataa tggtaacgca tgaccaagaa gaagctcttt gtttagctga taagatggtt
    20941 gttatgaata gaggagaaat aatacaagtt ggaacgccaa aggaggtata taaaaatcca
    21001 gaaacacctt ttgtagctga ttttatagga acaataaatt ttatagatga tggtattaat
    21061 aagatagcta ttagaccaga agatataaaa gtagagtcta acagagattc taaagataag
    21121 gatataaaag tgggagaaat tttagatatc gaatttagag gatttaacta tagaattaca
    21181 gttgagtatc gttctaagca aatgaaatta gatgtagttt ccaaagttgc agaacaaatg
    21241 aaactgtgca taggttctaa aataaacttt aagataccta aagaaggaat tgtacaatat
    21301 aaatcagagg gatgtgctta atagctaggg gtgaataaat gataacatca aaaaataaaa
    21361 gaagaataag tgatagcaca atacaaaaat atttcttgat tttttcggta attgtactaa
    21421 tagtatttat attatttcca ttagtatcat tattaaaaaa tgcatttatg gatacaagtg
    21481 gaaattttat aggaatttca aattttagta aatatgttga aaatccaagt cttatagcat
    21541 catttaaaaa ttcaattttt gtatctacag tctcatcttt aatatcacta tgtttagcat
    21601 ttatatattc atacgcaata acaagaacaa acataaagtt taaagatttt tttaaaacta
    21661 tgggaatgtt tccacttttt gcaccaacta tgttatatgg tatttcactt atataccttt
    21721 ttggaaataa gggaatcttt acaaccatgg gtctggaagt accactatat ggtccattag
    21781 gaataattat ttctcaaatt ctatttacat ttccacaagc ttttttaata ttatctgtag
    21841 cactttcgat ggctgattac agactttatg aagcagcaga tagcttgggt gctagtgaat
    21901 ttaagaaatt ttgcaaaata acaattcctg gtataaagta ctcattactt agttcattct
    21961 ttgtatcctt tatacttgca tttacagatt ttggagcagc taaggtagtt ggaggaaact
    22021 acaatgtact ggccactgac atatataaac aagtagttgg acaatttaac ataccaatgg
    22081 gagctactgt ttctatggta atgttaattc ctgtactaat agcatttaca ttagataaga
    22141 tggcaagtaa gaaacaaggt atgaccataa ctgcaaagtc tatgccatat aagattaagg
    22201 aaaataagtt tagagataga gtatttttaa tagtatgtag ttttataaca ttgctaattt
    22261 ttattttaat attcgtttca gttataggtt cagttataaa gttatggcca tataatttaa
    22321 gctttacaat ggaacactat acatttaaag gtattttggg aagtggaata aaaacatact
    22381 taagcagttt gaaaatatca actttaacag caatatttgg aactatattt gtatttttta
    22441 gtgcttatat gatagaaaag gtggataagt ttcctaaatt aagacaaaca gcttaccttt
    22501 tatcaatgat accaatggcc ttacctggct tagttttagg tatatcatat ataacttttt
    22561 ttaactcagc aagtaatcca ttaaattttt tatatggaag tacagcaata ttagttatag
    22621 taaatgtagt tcatttttat tcagtttgtt ttataacctc aaattcatct ttaaaaatgt
    22681 tggataaaga gtatgaatta gttgcaaaat ccataaatat tccattctat aaagtatttt
    22741 ttaatataac agttccaatg tctataacat caatacttga aatagtagta tattattttg
    22801 taaattcaat ggttactgtt tcagcattaa tatttttata tacacctcaa actcagactg
    22861 catcaatatc aatactaaag ttagatgaga taggatatat aggaccatca gctgctatgg
    22921 cagtattagt gcttttaaca aatataatag taagactttt gtacgaattt gtaacaaaga
    22981 aattaaaaaa taacacacaa aaatggcagc aaaaagatgt tgcatagggg aggtaaaaat
    23041 gaaatttaag aagctagttt ctttaggagt attatcaaca cttttattaa gtgtaataac
    23101 aggatgtagt actgattcat caggttcaga ttcaaagtct gatagtaaga caaaagggga
    23161 tttaacagtt tacacagcaa ttgaagaaga tagtatagag ccatatttag ctacatttaa
    23221 agagaaatat ccagatatta aattaaatat tgttagggca tcaacaggag atataacagc
    23281 aagattatta gcagaaaagg ataatcctca agcagatgtt gtatggggag ttgcagccac
    23341 aagcttattg gttgcagatg accaggggat gttagaacca tatgctccaa aaggttctga
    23401 agaaatagag tctgcattta aagatgataa agaagttcct tcttgggttg ggatagatgc
    23461 ttggatgaca ggtataacag taaacactaa agaattaagt gataagaaca tcccagttcc
    23521 tagttcttac gaagatttaa taaagccaga atataaaggt cttatatcta tgcctaatcc
    23581 atcttcttct ggtacagggt acttaacagt atcagccctt atacaaatta tgggggaaga
    23641 aaaagcatgg cagtatatgg ataagttaca tgagaatatt ggtgtataca ctcaatctgg
    23701 ttcagctcca gctacatcag cagcttcagg agaatatcct attggtatat cttttggata
    23761 tagaggtata aagttaaaag aggaaggcta tccagtagaa gtagtatttc caaaagaagg
    23821 ttctggatgg gatatagaag caaatgctct tgtgaaaaaa gataatataa aagaagcatc
    23881 aaaagtattt ttagattggg ctataagtaa agatgcaatg aacgaatact ctaaaaacta
    23941 tgcagttact actatttcta caggaaatcc aataccagaa ggattcccta aaaagccatt
    24001 agagcaaatg atagataatg atttaaaatc agcagcaaaa aatagagaag atatactaaa
    24061 taaatggata tcaaaatatg atggtaagac agaaaaagag agttaagtaa aactatacaa
    24121 atggagtaaa aagaaaaatt tttttaagta gattttatta taataatata agttgagaat
    24181 aatataggtc aagaaaagtg aatattctat aaaaatgtat agagtaagta taccattcag
    24241 tttgaatggt atatttttta tttttagaga ttaatttaga aatagatata ctacagttta
    24301 aaatagtata ttt
//
LOCUS       DAEOTL010000054        24220 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEOTL010000054 DAEOTL010000000
VERSION     DAEOTL010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24220
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.054"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            311..913
                     /locus_tag="KRH82_002566"
     CDS             311..913
                     /locus_tag="KRH82_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8655839.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEDSRQFAKQIYYILDNSIEVDNC"
     gene            complement(1176..2378)
                     /locus_tag="KRH82_002567"
     CDS             complement(1176..2378)
                     /locus_tag="KRH82_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8655840.1"
                     /translation="MTAKKSNEKRRDNKGRNLRIGESQRKDGRYAYKYIDALGKPKFV
                     YAWRLVPTDKTPAGKRDDISLREKEKQIQKDLDDGIDTNGGKMTVCQLYAKQIRQKGN
                     VRLGTKKQRQYLMELLKNDPLGSRSIDSVKPSDAKDWAIRMKGNGVAYSSINNYKRSL
                     KASFYMAIEDDYIRKNPFNFDLNTVIENDTKPKEALTEEQEANLLAFVKEDKVYKQYY
                     DEIVILLGTGLRISELCGLTTKLDMQNRIIDVDHQLLRDSEIGYYIETPKTKNGVRQI
                     PMSEEVYQAFQRVLKNRQKAEPIVIDGYRNFLFLKKDGFPKVACNYQSMLSSLVKKYN
                     KTHKEALPHITPHTLRHTFCTRFANAGMNPKALQYIMGHANITMTLNYYAHATFTSAK
                     AEMMRLVA"
     gene            complement(2459..2662)
                     /locus_tag="KRH82_002568"
     CDS             complement(2459..2662)
                     /locus_tag="KRH82_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBG8655841.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRRIAEDNLASGWVI
                     MNGNRLQIKRKQFEKIVDTLDEI"
     gene            complement(3062..3310)
                     /locus_tag="KRH82_002569"
     CDS             complement(3062..3310)
                     /locus_tag="KRH82_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655842.1"
                     /translation="MSKSSAVHKENGLLPYPVIVSASQGDIIAMGIVLTHYEPYIARL
                     SLKTVFDDYGYPHTCVDEDMRRRLESKLIEKVLDFKVA"
     gene            complement(3303..3731)
                     /locus_tag="KRH82_002570"
     CDS             complement(3303..3731)
                     /locus_tag="KRH82_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8655843.1"
                     /translation="MKRATSHEEGKQRSFDCYCKRVLKHEAIDIQRHNQYLNTVQVSL
                     SELTPEQENELCTFDEYSTDYQNFKVLEYDIAVRDELLAEALQELPEKKRDIVLLSYF
                     LDYTDVEIADLLKIVRRTVNDQRNKALKELRERMEGKKHE"
     gene            complement(4187..4558)
                     /locus_tag="KRH82_002571"
     CDS             complement(4187..4558)
                     /locus_tag="KRH82_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655844.1"
                     /translation="MKQSEHLKTEEKIFLSLCCQHDRDILTGKVDMSLQDFERITYLA
                     MVLGYVNYTIALNEQYLDFANILSEQIDRENEILEEYPDYYIDEEIDILYQKWIDDFL
                     SHVPADKQAYCLEQLKNNAQT"
     gene            complement(4578..4802)
                     /locus_tag="KRH82_002572"
     CDS             complement(4578..4802)
                     /locus_tag="KRH82_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005341955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655845.1"
                     /translation="MIGFKKRDTKAIFKAIARQEGVSVAEVIREMEFSIEDAKNNLDP
                     EKQTEFKRLFGNRTPTPEEFVYTVAKKLKY"
     gene            4957..5325
                     /locus_tag="KRH82_002573"
     CDS             4957..5325
                     /locus_tag="KRH82_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655846.1"
                     /translation="MELDFKAIGKRIKIARIRTNLTQETVADKIGVTPQHVSNIETGN
                     SSVSLTTLVAIANLLNVSVDELLCDTVLKSKAVFIKEADDIFKDCNEYEVRVLVDVLK
                     ATKSSMRNIKLFESSMNKNE"
     gene            complement(5363..5854)
                     /locus_tag="KRH82_002574"
     CDS             complement(5363..5854)
                     /locus_tag="KRH82_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBG8655847.1"
                     /translation="MLVKRLINGVLNQNNKSFNKQKEVLSYGKILVVSLSDNDEQIFN
                     QTVKWLSDKLNCSAVVLEPQQQGFSIDPYTRTFITEYGKIVYLTAKEFDLLYFLYSHK
                     GQVFTKEQLYEKVWGYEDMTDGSNLTSFIRKLRKKIEPTPDNPQYIITVWGVGYKFNE
                     EKP"
     gene            complement(5811..7553)
                     /locus_tag="KRH82_002575"
     CDS             complement(5811..7553)
                     /locus_tag="KRH82_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017210303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655848.1"
                     /translation="MWGVVKKIILLSGDKARSVKASILVALIYAIFVALPYMAVYVFF
                     DDSLNNQLTSNTIYKCIIIMIISLIGGSIAKTITYRLQEWASNYVSAKERLDIGDRLK
                     RVPMGFFREKTLGEVTAILTSDLTYYENKAADVLDWVVNGVISSLISCVFLMIFNWRL
                     GMIFTLGFIVSLMILNKMQSKSAEIVPLQKNAETDAISATLEFIRGISVFKLFHMSGN
                     SVNAVKNSYKQYSDISYDLEVKLLPWNTFALCWLKLVISSILLSVPFLASKGIIDVST
                     AIMMIVASLQIFSPLETLVTSIASIRTMDTVIDRIEKIKSFPMIDEDSEDITLDSFDI
                     VFNNVSFSYDNKNDVVKNISLKIPQNTMTAIVGSSGSGKTTMARLIARFWDVQNGSIE
                     VGGVNIKNLTCDSLLRNISIVFQNVYLFNDTIESNIKYGNPNATHEEVVTASKKACCH
                     DFIMALPDGYDTIVGESGSHLSGGEKQRISIARAILKNAPIVLLDEATSAIDPDNEVA
                     IQQAINELVRDKTLIIIAHRLTTIKEADQIVVMDNGSIVEKGTHNELLRMQGQYSKFW
                     NISQKANQWCAKSE"
     gene            complement(7541..9313)
                     /locus_tag="KRH82_002576"
     CDS             complement(7541..9313)
                     /locus_tag="KRH82_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017210302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655849.1"
                     /translation="MKNKQKNPLFQILDFASDYKGKMIIATVISVLSVFLGIVPYITM
                     GKILIYLIDGNVRLERILVLAGLTALSLIIEKVLYSISTWISHKVAFGTLCSIRCSLV
                     DKLEHTSMGYIQNRESGSFKQNMIDLVDRLEDALAHLIPEVIPNVILPIIVLLYLFVL
                     DWRIAFASLASIFIGAVTWSLMMGKNAMDIFQLTQEGTENMNSTIVEYVNGMEIIKAF
                     NQTASSMKRYENAVIKYRDALVRWFHHVWPYLSVYGVVTPATIAFVLPVSGILLFNGA
                     IDMHTLITCLVLSLGIVQPIMKIVSFTDHINELYTANTKIQEILNAPELVQSSKFVSI
                     NNNSVELKNVSFGYGEQEVLHNISFKVNAGTTTAIVGSSGSGKSTITKLIARFWDVDK
                     GQILIGNMDIKDIPFEQLMSYISYVSQDNFLPNITIRENIRMGKPNASDEEICLASKK
                     ACCDEFIRQLPNGYDTKVGDAGDKLSGGERQRIAIARAIIKNAPIVILDEATSAIDPE
                     NEYLIQKSIDELTKGKTLIIVAHRLSTIMYSQQIIVVDKGEKIAYGTHAELLESCPIY
                     KSMWDNHIGASGWSIRKGVSLCGE"
     gene            complement(9341..9934)
                     /locus_tag="KRH82_002577"
     CDS             complement(9341..9934)
                     /locus_tag="KRH82_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011989380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8655850.1"
                     /translation="MMPQIFSAKERTKLKNEMLSVGFELLKQYGMTHTSVEKVTKAVG
                     LGRSTFYNFFGTKEEFIYEIICFQREKAMVKFRQILNGREKMTVSEAKEYLKYLYSGE
                     DTIYPYLTTEDESKLQKALPDDFKIDVDIEIKTIDSFLIHMENVKENLDYKVIANLMK
                     TLALIQEANDMLHQDAIPRTLDAMFELLFSLIFNNDD"
     gene            complement(10087..10455)
                     /locus_tag="KRH82_002578"
     CDS             complement(10087..10455)
                     /locus_tag="KRH82_002578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655851.1"
                     /translation="MLVFGLTGCGTAEDKSNSNTVMDYTNNFVGTWEADFSDFDVYVE
                     QGITGVAKSEFDKDGNLTTYLDGKKDGTFGYFVYKDYYVAIGEDGSAEVTQYKFSDNG
                     STLEFSDLEGNWMLTYTKTK"
     gene            complement(10629..11531)
                     /locus_tag="KRH82_002579"
     CDS             complement(10629..11531)
                     /locus_tag="KRH82_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8655852.1"
                     /translation="MFKKKEKKAETVKEKKVPTMKIGTHKKTVIVLWAVLIGSLAFGV
                     YKNFTAIDMHTVHEKEIIQLKLNDTNGIENFVKNFAKSYYTWNNSQEAIDARTSAISH
                     YLTQELQDLNADTIRTDIPTSSAVSDVIIWSVEQSGDSEFITTYEVDQQITEGDQTKA
                     VKATYTVAVHVDADGDMVIVKNPTLAPAYEKSSYEPKLTETDGSVDAVTMQDATSFLE
                     TFFKLYPTATEKELAYYVNGNVLEPINGDYLYSELINPVFIQDGDNVKVKVSVKFIDN
                     QTKATQISQFDLTLHKDGNWQIIR"
     gene            complement(11548..12138)
                     /locus_tag="KRH82_002580"
                     /pseudo
     CDS             complement(11548..12138)
                     /locus_tag="KRH82_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            complement(12240..14057)
                     /gene="ltrA"
                     /locus_tag="KRH82_002581"
     CDS             complement(12240..14057)
                     /gene="ltrA"
                     /locus_tag="KRH82_002581"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBG8655853.1"
                     /translation="MKKTNKLRYAEYYDMQSKLDQLYMQSKNGNNFYKLTKLMESEEN
                     IRLAYRNIKKNMGSHTAGVDGKTIADIEDLTVEEVVTKIREMFKWYEPEKVRRVYIPK
                     PDGRKRPLGIPAIWDRLFQQCILQILEPICEAKFHPHSYGFRPNRSAHHAIARANHFM
                     NNKGNGYHYCVDMDIKGFFDNVNHGKLLKQMWTMGIREKKLLSIISTLLKAEIIGEGK
                     PIKGTPQGGILSPLLANIVLNELDWWISNQWETIKTIREYTTHKGARRALMRQRKNLK
                     HCYMVRYADDFKIFCRDYPSALRLYHATQDFIERRLKLEISPEKSKIVNLRKQRSEFL
                     GFTMYVRPKRNGYVAYSHMSDKAIRHAHDKLKQSIKRIAKEQSRDAVWKYNTVVMGIH
                     NYYEVATHVNRDLAHMSQHLTKSLYNRLRRDWRPASKADLSITLLKRYGRYNPKWYKA
                     HDMIIIPIYTWKHRYAIQFNQNICPYTKEGRALIHNNLKAVSREVLIHIQRYYCDYRS
                     IEYNDNRISKFISQYGKCAISGEELTLRDWECHHKVPLKYGGTDKYNNLIIMILPFHK
                     AIHKRDRKELDNLMEKYQLSEQKRKLCIELHELANQSEK"
     gene            complement(14248..14484)
                     /locus_tag="KRH82_002582"
     CDS             complement(14248..14484)
                     /locus_tag="KRH82_002582"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655854.1"
                     /translation="MYGSITLMHRNVYATCVVSVRTSKISCYENPFIVKGSNKLTGSK
                     ENPKSICKDKSNGTLEAANMEKISSMKWLKGNLL"
     gene            complement(14783..15214)
                     /locus_tag="KRH82_002583"
     CDS             complement(14783..15214)
                     /locus_tag="KRH82_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBG8655855.1"
                     /translation="MRIKHIAIVSSIFPILFAILLFFGILISAEDDDGSVSYSSGVTG
                     MNLSAEVLKHQPTVEKYAKEYGISEYVPYLMAIIQVESGGTATDVMQSSESMGLPPNS
                     LGTEESIKQGCKYFASLLSSAQSKGCDMNTVVQSYNCVKRS"
     gene            complement(15211..17382)
                     /locus_tag="KRH82_002584"
     CDS             complement(15211..17382)
                     /locus_tag="KRH82_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008977175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8655856.1"
                     /translation="MKERLQGLLTRKKLFHFVKVAVIVIATTVVTLSLLGTVAHATGL
                     VDDTVSAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWII
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTIAGVTKSGFSSSGFYVGFLLMIIL
                     VVGIYVAYTGLIKRETTKAIHAVTNFLVIFLVSASFIAYAPDYIKKVNDFSSDISTAS
                     LDLGTKIMLAGSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGDSNKEEIGTDRVEALV
                     SVSPSDDDGETREDVVIAEIETFDNDNLTIPQVMNRLGMVFFLLIFNLGITVFVFLLT
                     GMMIFSQILFIIFAMFLPVSFLLSMIPTYENMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNMSDDYPFFMVAFLQIVTFAGIYMKLGDLMSMFSLNASDSQNMGRRMFRRP
                     MMFIRHRTRRMERRLARAVGAGAGAGAVAGSMLSNTSGSSRSGTSKPQRSNTASSMGS
                     KAGSAVGAVLDTKNRIRDKATAVKESVKDMPTQAGYAVHSAKERAKENVSDFKRGVIK
                     EQQDRQAGRADKLNQHRQSIADKRMTMQKAQEERQSAKRSDGSATAGATRPHERPVTA
                     SAKSEKRPVTSKTPSADTEKPPTVKERPVTGGAVSKVPEPKETIQRPSMKPSEKSSAV
                     REQTTRQAVKNKRTVKSQQTKQVQKKSTPAKGSTPKKGRKP"
     gene            complement(17383..19833)
                     /locus_tag="KRH82_002585"
     CDS             complement(17383..19833)
                     /locus_tag="KRH82_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8655857.1"
                     /translation="MFHIKYIDNNLVWNRDGEVFAYYELIPYNYSFLSAEQKFIVHDN
                     FRQLIAQNREGKIHALQIATESSIRSIQEQSKKLVTGRLRDVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEQNVSLDSMKQSAFLTFKEFIGEVNHTLMNDFVSISNDEI
                     NRYMKMEKLLENKISRRFKIRRLEKNDFGYLIEHIYGRDGVAYEDYEYSLPKRKMKKE
                     TLIKYYDLVRPTRCLIEESQRYIRLEHEDTESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPIDTSMNVEIVENRKALSTVRNKKKELKDLDNHAYQSGSETSSNVVDALDSVD
                     ELEADLDQTKESMYKLSYVIRVSAPDLDELKRRCDEVRDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASRRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYIGYSVDTGRNVYLQPS
                     LASQGIKGTVTNALASAFVGSLGGGKSFCNNLIVYYSVLFGGQAVILDPKSERGSWKE
                     TLPEIAHEINIVNLTSDSMNKGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVAQSPTRGLLHVIDELRKEDTPISRNIADHIDSFTDYDFAHLLFSDGNV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSGDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKEDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVKQSEVG"
     gene            complement(19811..20209)
                     /locus_tag="KRH82_002586"
     CDS             complement(19811..20209)
                     /locus_tag="KRH82_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8655858.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDLPPLSMIDGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQKFNETITAVRSVMYVPHKIY"
     gene            complement(20323..20826)
                     /locus_tag="KRH82_002587"
     CDS             complement(20323..20826)
                     /locus_tag="KRH82_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8655859.1"
                     /translation="MVDDMRVYIANLGKYNEGYLVGDWFSFPLDYEEIKERIGLNGEY
                     EEYAVHDTDNFPCEVSEYISIDELNRMYEMIEELPEEVVDSLDDFISYYGSLEGVVEH
                     KDQIYFYPDCDSMEDVARYYVDELHTLGDIPPSLEYYIDYEAYGRDLEIEGYFIETSY
                     GMCEIQR"
     gene            complement(20842..21339)
                     /locus_tag="KRH82_002588"
     CDS             complement(20842..21339)
                     /locus_tag="KRH82_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8655860.1"
                     /translation="MNELRVLIEAKQSADSERRSAWFTLPIDEEELEETLGIEADSDA
                     YRIIEKDVPFADDVGEDTPVERLNDLCDMYENLPSELQDEYSELMCHFSSLDELHQHR
                     YDIIHYPDCNSMTDIARRCLAENPAFTSLSEDCVRYFDFEAYGQYLDDNGTFVETDHG
                     IYELP"
     gene            complement(21332..21556)
                     /locus_tag="KRH82_002589"
     CDS             complement(21332..21556)
                     /locus_tag="KRH82_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655861.1"
                     /translation="MIHKDIFSDMLAKTGCRYISDLPYCKRAVWFEVKLLSLADYPRQ
                     QLEDFSRYVFGVPYTVIAQVLQRKDVKTIE"
     gene            complement(21638..21859)
                     /locus_tag="KRH82_002590"
     CDS             complement(21638..21859)
                     /locus_tag="KRH82_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655862.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALISVGLVFNAGGVKDVLLQLFNKIIGA"
     gene            complement(21856..21993)
                     /locus_tag="KRH82_002591"
     CDS             complement(21856..21993)
                     /locus_tag="KRH82_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018595058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBG8655863.1"
                     /translation="MWNVLSKFLLFSSGAIFGVVLMCLLQAGKEADKRMEKINDWRND
                     K"
     gene            complement(22011..23201)
                     /locus_tag="KRH82_002592"
     CDS             complement(22011..23201)
                     /locus_tag="KRH82_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBG8655864.1"
                     /translation="MNENDWINALKEKRLSFGVSQSRLAIMAGISREYLNRMEMGKVR
                     PSKEVRDKLMEALEKFNPDNPLTMLFDYVRIRFPTTDVQHVIHDILKLNIKYMLHEDY
                     GHYTYAEHYYIGDVFVYASQEQEKGVLLELKGKGCRQFESYLLAQERSWYDFFMDALI
                     EGGVMKRIDLAINDRTGILDIPELMEKCKYRECVSLFRSFKSYASGEFVKHDEQDKAG
                     MGHTLYIGSLKSEVYFCCYEKNYEQYVKLGIPIEESPIKNRFEIRLKNERAYYAVRDL
                     LTTYDAEQTAFSIINRYIKFVDKEAGKSQNQWKLNDRWSWFIGKDRPPLKLTTQPEPY
                     TLERTMSWIARQVAPTLKMLKKIDAGNGTDFLKHIEEQAKLSEKHEKIIKQQTTSTEE
                     IVLK"
     gene            complement(23265..23421)
                     /locus_tag="KRH82_002593"
                     /pseudo
     CDS             complement(23265..23421)
                     /locus_tag="KRH82_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002907732.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(23391..>24220)
                     /locus_tag="KRH82_002594"
     CDS             complement(23391..>24220)
                     /locus_tag="KRH82_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8655865.1"
                     /translation="LLYDMIANRITIDEVQAENGCLRLMKNLVWEYDALPHALIAGGT
                     GGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVYHTKEEMIDCVNAFYE
                     GMVQRSEEMKQHPNYKTGENYAYLSLPPCFLIFDEYVAFFEMLGTKESVSLLSQLKKI
                     VMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISELGYGMLFGSDVKKQFF
                     QKRIKGRGYCDVGTSIISEFYTPLVPKGYDFLQTIGSLAYARQDGTATCEAKGDGTD"
BASE COUNT         6764 a         5291 c         4364 g         7801 t
ORIGIN      
        1 tataaattta tagtcttcat ttgagtacat attttttacc tccaagattt taaatataat
       61 cataaattaa gcaattataa tcctataaga taattttaca ataaattacc atagttaact
      121 acacacatat atgtaaaaac atacctaaaa tatttttaat tatagataca ttccaacttt
      181 tattgataaa acaatttgtt tcaattttat tacaaatata caaagtgtat tgttgttaac
      241 gtattctcat agtatcctaa aactatatta agcactaaaa actattttaa aatactgtgg
      301 aggtatcaat atggaagtat gcattcttat gggaagtcct aagaaaaaag gtaatactgc
      361 tgctatttta aaacctttta ttgaggaatt agaaaattat aattcaaata ttgaagtaat
      421 atggttatat gattgtaaaa tagagccatg tattgcttgt aaaaagtgtc aggataactt
      481 atttgatttt ggatgttatt gtaaagatga tgttcagaaa attttcaaga aaattcttat
      541 gtgtgattta attgtttttg ctactccaat ttattcttgg tactgcactt ctccaatgaa
      601 agcactactt gacagattgg tgtatggaat gaataaatac tatggtaatg agaaaggccc
      661 cgctctatgg gcaggaaaac cagtagcact tattacaaca tgtggatata gacctgaaaa
      721 gggtgctgat atttgggaaa atggtatgaa gcgctactgt aagcattcac agttaaaata
      781 tataggaatg cttgttgaac gtgatttagg taaacctaat tttatgaata aagaaaaaga
      841 agaagattct cgtcaatttg caaaacaaat ttattatatt ttagataatt caattgaagt
      901 agataactgc taaagacata atactccaag taaagtattg ataatataaa taaatcttac
      961 ataatttgct tatttaaaat aagatatata ttagaataaa gaataacacg attttttgat
     1021 tatcttttca taagttggta aatgtcggtt tagcctgtat ttatgggctt tatcggcatt
     1081 tcccatatcg gaagatactc ggcataagct ggcatttacc agcatgaaaa tgcaatcaaa
     1141 agtagtaaat gtgtagtaaa tttcctttta ctactctatg caaccaacct catcatttcc
     1201 gctttcgcag atgtgaatgt cgcatgagca taatagttca gcgtcattgt gatgttggcg
     1261 tgtcccatga tgtactgtaa cgctttaggg ttcattcctg cattggcaaa acgagtacaa
     1321 aaggtatgcc ttagagtgtg tggcgtgata tgcggtaatg cttctttatg tgtcttgttg
     1381 tacttcttaa caagactact cagcatactt tgataattgc aagccacttt tggaaagccg
     1441 tcttttttaa gaaacaggaa atttctgtaa ccgtctatga cgattggctc ggctttctgg
     1501 cggttcttca atactctttg gaacgcttga taaacttcct cgctcattgg aatctgtcgg
     1561 acaccgttct ttgttttggg tgtttcaatg taatacccga tttcactatc tctcaatagc
     1621 tggtggtcta catcaattat ccgattttgc atatccagct ttgtagtcag accgcataat
     1681 tcagagatac gaagtcctgt cccaagcagt attacgattt catcataata ctgtttatag
     1741 actttatcct ccttgacaaa ggctaacaga ttagcttcct gttcctcggt caaggcttct
     1801 tttggtttcg tgtcgttctc aatgactgta ttcaaatcaa aattaaaagg attctttctg
     1861 atatagtcgt cctcaatcgc catataaaat gacgctttca gagaacgctt atagttgttg
     1921 atagagctgt aagcaacccc gtttcctttc attctgatag cccagtcttt agcgtctgac
     1981 ggcttcacac tgtcaatgct tcttgacccc aaagggtcgt ttttcaaaag ctccataagg
     2041 tattgacgct gtttctttgt tccaagtcgg acatttcctt tctggcgtat ctgtttagca
     2101 taaagctggc agaccgtcat tttaccaccg tttgtgtcga taccgtcgtc aaggtctttc
     2161 tgtatctgtt tttccttttc acgaagcgaa atatcgtcac gttttcctgc tggtgtcttg
     2221 tcggtaggaa caagtcgcca agcataaaca aatttaggct ttcctaatgc gtctatatat
     2281 ttgtatgcgt atcttccgtc ttttctctgg ctctctccaa ttcgtaaatt gcgacccttg
     2341 ttatcacgtc ttttttcgtt tgatttttta gctgtcatgg tagcaagctc ctttccaaaa
     2401 ttggaatgag cctagatacg ctatacatat attataccat attctaggct ttttttcatt
     2461 agatttcatc taatgtgtca acgattttct caaactgttt tctctttatt tgaagcctgt
     2521 tcccgttcat aatgacccag ccagaagcaa gattatcttc cgcaatccta cgcaatttct
     2581 tttccccaat acgaaaatat tttgacgctt cttcaatcgt tagcgtgtat ttttcccaga
     2641 ttggcacatc agtattgttc ataatatagc acctccttta ctgtgtgtcg tcggaagcag
     2701 acagacggct tttggcaagc tccgctagta tcacaactat tctcattcct atgagtgaac
     2761 ctcctttggg acgtatcatt atcctgcaat acaggtcatg gcagagcgac cattccaaaa
     2821 gtcgctccca gatcattgca tgaatcgctc gctttgtttt gaaaggtcgt ggcgtacaat
     2881 ttctgctggc tcactgtatt acaaacgtat ctgtctgctt tattcagttt tcaaggagct
     2941 atcggcttat cagcctttca aaacctatct ttcatcagat aaattttgaa agagtggtaa
     3001 atctgttcca gacagaggac gcaggaaagg gggtaatgcg tcactccgca ggataaatca
     3061 tttatgcgac tttgaaatca agcacctttt caatgagctt gctttccaaa cggcgacgca
     3121 tatcctcatc aacacaggta tgcggatagc cgtaatcatc aaatactgtt tttaatgata
     3181 atcgggcaat atatggctca tagtgtgtca gtacgatacc catagcgata atatccccct
     3241 gtgaagctga cacaatgaca ggatagggca aaagcccgtt ttctttatgt acagcactac
     3301 ttttactcat gcttttttcc ctccattctt tctcttaatt ctttgagggc tttattacgc
     3361 tggtcgttga cagtcctacg aacaatcttc aacaggtctg caatctcaac gtcggtatag
     3421 tccagaaaat aagagagcag gactatatca cgtttctttt ctggtagctc ctgcaaggct
     3481 tccgccagca attcgtccct caccgcaata tcatattcga ggactttgaa attctgatag
     3541 tccgtcgaat attcatcaaa ggtgcatagc tcattttcct gctctggggt aagctctgac
     3601 aatgaaacct gtaccgtatt caaatactga ttgtgtcttt gaatgtcgat agcttcatgt
     3661 ttcaaaactc ttttacagta gcagtcgaat gaacgctgtt tcccttcttc atgggaagtg
     3721 gctcttttca cagtttcacc tcctttcgtt tgtcaaaagg cggtgataaa aacctttcct
     3781 tccccctttc cgccattagt acgaatggga ggtagtcgat tggcaatctt tgagaaagaa
     3841 attcagaaaa cacaaaaaag ctcaaacagg taaaaaatcc cttttgagct tcttttaatc
     3901 cagccgacca tttctgataa aattctacaa agaatacagt gcaaaatccc catgcacata
     3961 aattgatttt tttgataatg ctttaagcaa cgcttgtccc ttatgatttc ttttcaatct
     4021 ctaaacctcc cttgcggaaa agttctcttc aagagaacag gtaaaattcc actggataat
     4081 cataaacgac aaatccgtcc aaattcctac catattcctg tttttttggc aggatatgag
     4141 aaaaggtcat tgcagatcag ctttaagctg gagcaataac ctttttctac gtttgagcat
     4201 tattctttaa ttgttcaagg cagtatgcct gtttgtcagc aggaacatga ctaagaaaat
     4261 catcaatcca tttctgatat aatatatcta tttcttcatc aatgtaatag tctgggtatt
     4321 cttctaagat ttcattttct ctgtcaatct gttcagacag tatatttgcg aaatctaaat
     4381 attgttcatt taaggcaatc gtataattca catacccaag aaccatagca agataagtaa
     4441 tgcgttcaaa atcctgtaag ctcatgtcta ctttacctgt caatatatca cggtcatgtt
     4501 gacagcatag agataagaat atcttttctt ccgttttcag atgttccgat tgcttcatag
     4561 cgtgtcctcc aaacgactta atatttcagc tttttagcga ctgtatagac aaattcttct
     4621 ggggtaggtg tcctgttccc aaacagcctt ttaaactctg tctgtttctc tgggtcgaga
     4681 ttgttctttg cgtcctcaat ggaaaattcc atttccctta tgacttccgc aaccgaaaca
     4741 ccctcttgac gggcaatcgc tttaaatatc gcttttgtat ctcttttttt aaagccaatc
     4801 atactataca cctcttttct gcaaattatg cttgaaatat ggaaaatgag taaaactata
     4861 actaatggaa tgattaactt tatgaaacca ttataataca atctcacaaa ggttacaatg
     4921 tataaaaata cttttgttga aaggagtgtg ccagctatgg agcttgattt taaagccata
     4981 ggtaaaagaa tcaaaatagc aagaataaga acaaatctga cgcaggaaac cgttgctgac
     5041 aaaataggtg tcactccgca acacgtcagc aatatagaaa caggaaattc cagtgtcagt
     5101 ctgacaaccc ttgttgccat tgcaaatctg ctaaatgtat cagtagacga gttgctatgt
     5161 gatacagtat taaaatcaaa ggctgtattt attaaagaag ccgatgacat attcaaggat
     5221 tgtaacgaat acgaagtcag ggttttggta gatgtattga aagctactaa aagctctatg
     5281 agaaacatta agttgtttga atccagtatg aacaaaaatg aataaaaccg tagttgacag
     5341 atcacacgaa tgtgaattgt aactacggtt tttcttcatt gaatttgtag cctacgcccc
     5401 aaacagtaat aatatactgt ggattgtctg gggtaggctc tatctttttt cttagtttac
     5461 gtataaatga tgtgagattg cttccgtctg tcatatcttc atatccccat actttctcat
     5521 aaagctgttc ttttgtgaat acttgtcctt tatgggaata aagaaaatat agtaggtcaa
     5581 attctttagc tgtcagataa acaatctttc catattcagt aataaaagtt cttgtataag
     5641 ggtcaatgga aaatccttgt tgttgcggtt cgagaacaac cgcagaacaa ttaagtttat
     5701 ccgacaacca tttaacagtt tgattaaaaa tctgctcatc attgtctgaa agcgaaacaa
     5761 ctaatatttt cccatatgac aacacctctt tttgtttatt gaatgattta ttattctgat
     5821 ttagcacacc attgattagc cttttgacta atattccaaa acttagaata ttgtccttgc
     5881 attctcaata attcattatg agtacctttt tctacgattg aaccattatc cattacaaca
     5941 atttggtcgg cttctttaat tgttgttagt ctgtgtgcaa taataatcaa agttttatca
     6001 cggactaatt cgttgattgc ttgctgtata gcaacttcgt tgtcggggtc gatagcagaa
     6061 gtcgcttcgt ctaataaaac aataggggca ttttttaata tagctcttgc aatagatatt
     6121 ctttgctttt caccaccaga aagatgtgag ccactttcgc caactattgt gtcatatccg
     6181 tctggtaatg ccataataaa atcgtgacag caggcttttt tagaagcagt taccacttct
     6241 tcatgagtag catttggatt gccatatttt atatttgact caatggtatc attaaataaa
     6301 taaacatttt gaaatacgat agagatattt cttagcaagc tatcacaggt aagattcttt
     6361 atattaacac cgccaacttc aatactgcca ttctgaacgt cccaaaatcg agctatcaga
     6421 cgtgccattg ttgttttacc agaaccagaa gaaccaacaa tagcagtcat tgtattttgt
     6481 ggtattttca aagaaatatt ttttacaacg tcatttttat tatcatacga aaaagatacg
     6541 ttattaaaca caatatcaaa agaatccaaa gtaatatctt cgctatcttc atcaatcata
     6601 gggaatgatt ttattttttc tattctatca ataacagtgt ccattgttcg tatgcttgca
     6661 atagaagtaa ctaatgtttc aagtggactg aaaatttgaa gactagcaac aatcatcatg
     6721 attgccgtag aaacatcaat aataccttta cttgcaagaa aagggactga taacaaaata
     6781 ctagatatta ccaatttaag ccagcataac gcaaaagtgt tccacggcaa aagttttact
     6841 tctaaatcat aggatatatc actatattgc ttataactat ttttcacagc attaacgctg
     6901 tttccactca tatgaaatag tttaaataca gaaatccctc gaataaattc taatgttgca
     6961 gaaatagcgt ctgtttctgc atttttttgt aatggtacaa tttccgcact tttgctctgc
     7021 attttattta gtatcattaa cgatactata aagccgagtg taaaaatcat tcctaaacgc
     7081 cagttaaata tcataagaaa aacacaagat attaacgagg aaataacacc attcacaacc
     7141 caatctaaca catcagccgc tttattttca taatacgtca aatcagatgt taaaattgct
     7201 gtgacttctc ctaaagtttt ttcacgaaaa aatcccattg gaaccctttt taatctatcg
     7261 ccaatatcta atctttcttt tgctgaaaca taattacttg cccattcttg taagcggtaa
     7321 gtaattgttt ttgcaataga gccacctatt aaactaataa tcataatgat aatacattta
     7381 taaatcgtat tagaagtcag ttgattattc aaactatcgt caaaaaaaac atacacagcc
     7441 atatatggta acgccacaaa aattgcatat atcaatgcca caagaatact cgctttgaca
     7501 cttcttgctt tatcgccaga aagtaaaata atttttttga ctactcccca cataatgaca
     7561 cccccttgcg aatgctccag ccacttgctc caatatgatt atcccacata gatttataaa
     7621 tcggacaact ttctaacaat tcagcatgag taccatatgc aattttttct cctttatcta
     7681 ctacaataat ctgttgagaa tacataatcg ttgacaatcg gtgtgcaaca attattaagg
     7741 tttttccttt tgttaattca tcaatagact tttgtatgag atattcattc tctgggtcga
     7801 tagcggaagt tgcttcatca agaataacga ttggagcatt ttttataatt gctcttgcaa
     7861 tagcaattct ttgacgttcg ccaccagaga gtttatcgcc agcgtcacca actttcgtat
     7921 catagccatt aggaagttgt cttataaatt cgtcgcaaca agccttttta gaagcaagac
     7981 atatttcttc gtcagacgca ttaggttttc ccattcgtat attttctcga atggttatat
     8041 taggtaaaaa gttgtcctgt gatacataac ttatgtaact catcagctgt tcaaacggaa
     8101 tatctttaat gtccatatta cctataagga tttgtccttt atctacgtcc caaaatcgag
     8161 ctatcaattt cgttatagta gattttccgc ttccagaaga acctacaata gcagtggttg
     8221 ttccagcgtt tactttaaaa gatatattgt gtaaaacctc ttgttctcca tagccaaatg
     8281 aaacattttt taattcaacg ctattattat tgatactaac gaatttggag ctttgaacca
     8341 gttcgggagc attaagaatt tcttgaattt tggtatttgc tgtatataat tcgtttatgt
     8401 gatctgtgaa ggacactatt ttcataatgg gctgaacaat tcctaatgat aaaacaaggc
     8461 acgtaataag cgtgtgcata tcaatagcac cattaaataa tagtattcca ctcacaggta
     8521 aaacaaaagc gattgttgct ggcgtaacaa caccataaac acttaaatac ggccacacat
     8581 gatgaaacca gcgaacaagt gcgtcacggt atttaataac tgcattctca tatcgtttca
     8641 tagaagaagc agtttgatta aatgctttga taatttccat gccatttaca tactcaacga
     8701 ttgtagagtt catattttca gttccctctt gtgttagctg aaatatatcc attgcatttt
     8761 tccccatcat caagctccat gtaacagcac caataaaaat agaagcaaga gaagcaaaag
     8821 caattctcca atctaaaaca aatagatata ataatactat aataggtaat attacatttg
     8881 gaataacttc tggtattaaa tgagccaatg cgtcctctaa tctgtcaacc aaatcaatca
     8941 tattttgttt gaaagaacca gattctctgt tttgaatata tcccattgat gtatgctcta
     9001 acttgtccac aagagaacat cttatagaac ataacgtacc aaaagctacc ttatgagaaa
     9061 tccatgttga aatactatat aatactttct caataattag cgataaagcg gttaagcctg
     9121 ccaatactaa tattcgttct aatcgaacat ttccgtcaat taaataaatc agtatttttc
     9181 ccattgtaat ataaggaaca atccccaaaa atacagacaa tacagaaatg acagtagcaa
     9241 ttatcatttt acctttataa tcgcttgcaa aatccaatat ttgaaatagt ggattttttt
     9301 gtttgttttt cattaaaatc tcctttcttt ttgctcaaga ctaatcgtca ttattaaaaa
     9361 taagagagaa aagtaactca aacatagcgt ctaaagttcg aggaatagcg tcttgatgaa
     9421 gcatatcgtt tgcttcttga atcaaagcta atgttttcat caaattagca attactttat
     9481 aatcaagatt ttcttttacg ttttccatat gaatcaaaaa gctgtcgatt gttttaattt
     9541 caatatcaac atctatttta aaatcatctg gcaacgcctt ttgtaattta gattcatctt
     9601 ccgttgtcag atacggataa atagtatctt cgccagaata caaatatttc aaatattctt
     9661 tagcttcact gaccgtcatt ttttctcgac cattcaatat ttgtctgaat ttaaccatag
     9721 ctttttcacg ttgaaagcaa atgatttcat aaataaattc ttcttttgtt ccaaaaaaat
     9781 tgtaaaaagt acttcgacca agaccaactg ctttcgttac tttttcaact gatgtatggg
     9841 tcataccata ctgttttaat aactcaaaac ctacagataa catttcattt tttaactttg
     9901 ttcgttcttt tgctgaaaat atttgtggca taatatttct cctccttatg agatatttca
     9961 atttcaagcg acgattattt ttaaaattgt cgcataagaa gtataacata tcccctgcaa
    10021 ttattcaata aagcaatact tacaggggtg ttaaaatgtc tattcaaaat acaacaaaag
    10081 aacgaattat tttgtcttag tataggtcaa catccagtta ccctctaaat cactaaattc
    10141 tagggtactg ccattatctg aaaatttata ctgcgttacc tcagcagagc catcttcacc
    10201 gatagcaaca taataatctt tatagacaaa gtacccaaat gtaccgtcct ttttgccatc
    10261 taaataggta gttaagtttc catctttatc aaattcagat tttgcaacac cagtaattcc
    10321 ttgttctaca tatacgtcaa aatcactgaa atcagcttcc caagttccaa caaaattgtt
    10381 ggtataatcc attactgtat ttgagttgga tttatcctct gccgtgccac aaccagtaag
    10441 tccaaaaact aacataaata cagttaagaa gattgtaaaa attttttggt tttttgcatg
    10501 ttttgtcctc cttacgacaa tttgttatat atttagcgac aattaaatat aatattgtcg
    10561 ctaaatatag gttagcatag actaatcaga ttgtcaatat aaataaggtg ttttattact
    10621 gactattttt atctaatgat ttgccagttc ccgtccttat ggagcgtcaa gtcaaactgt
    10681 gaaatctgtg ttgcttttgt ctggttatca atgaatttca cggacacttt gacttttaca
    10741 ttgtccccgt cctgtatgaa cacgggattg ataagctctg aatacagata gtcgccgttt
    10801 atcggttcaa gcacatttcc attcacataa taggcaagtt ccttttctgt tgccgtaggg
    10861 tagagcttga agaatgtttc caagaaagac gttgcgtcct gcatggtaac agcgtcaacg
    10921 cttccgtcgg tttctgtgag ctttggttca tagctggatt tttcatacgc tggggcaagg
    10981 gtcggattct ttacgataac catatccccg tcagcgtcca catgaacagc tacggtatag
    11041 gttgccttga ccgctttcgt ctggtcgccc tcggttatct gctgatctac ttcgtaggta
    11101 gtgataaact cgctgtcgcc cgactgttcc acgctccata tgataacgtc actgaccgca
    11161 gagctggtcg gtatgtccgt tcttatggta tcagcgttca agtcctgcaa ttcctgtgtc
    11221 agataatgac tgatagctga tgtacgggcg tcaatcgctt cttgactgtt gttccatgta
    11281 taataggact ttgcaaagtt cttgacaaaa ttctcaatgc cgtttgtatc attcagcttt
    11341 agctgtatga tttctttctc atggacggtg tgcatatcaa tagcggtaaa gttcttatag
    11401 acaccaaacg ccagacttcc gataagcacc gcccataata caatgacggt tttcttatgt
    11461 gtcccgattt tcatggtcgg cactttcttt tccttgactg tttcagcctt tttctctttt
    11521 ttcttaaaca tgattttcaa atcctttcta ttgtttgatt cgtcctgcac cgattaagtg
    11581 ctgttgccag taggagcttg taaggtctgc atatccgata gggtcgccag catgatacat
    11641 cttgttattg ccgacgtaga ttccaacgtg cgtcacataa gttcctgcat tgtaagttga
    11701 gtggaaaaat acaaggtcgc cagcttttgc ctgtgacaag gatatgtgct gtgtcacatc
    11761 atactgtgcc tgtgcggttc tcggtaagct gataccagcc tttccgtagc accactgaac
    11821 cagacccgaa cagtcaaaag acgtgttagg gttgctaccg ccgtagacat atttccaccc
    11881 ttgatatttc agagcttcat tcattatcgc ctgtgccgtt ttatcatcaa actgtgcgac
    11941 ggtcagatat tgactgacaa gctccacata gaacatattc ccgtatttgt accgccagcc
    12001 accgttacgg gcaacggcta tcgggttgga gtaggtcact tttgcaccgc ccgatttatc
    12061 ctttgcgaaa ttctgtgcaa gctggaagct gtgctttttc ccgttccttg ccacataatc
    12121 aatgtaaccg cccccgtata gtgataggta attctttgat attatctccg aattttcccc
    12181 cactctacac cgtacatgag actttcacct catacggcgt gccatctact ccaatgtatc
    12241 tatttttctg attgattagc cagttcatgt aattctatac ataacttcct tttttgttct
    12301 gataactgat acttctccat tagattgtca agttcttttc tatccctttt atgaattgct
    12361 ttatgaaatg gtagtatcat aataataaga ttgttatatt tgtctgttcc accatatttc
    12421 aagggaactt tatgatgaca ctcccaatcc ctcaacgtta attcttcgcc actgattgca
    12481 cattttccat attgagagat aaattttgag atacgattat cgttatattc aatagaacga
    12541 taatcacaat aatatctctg tatgtgtata agaacttccc tgctcaccgc ttttagatta
    12601 ttgtgtatca aggctcttcc ttcttttgta tatggacaga tattttgatt gaattgtatc
    12661 gcatacctgt gtttccatgt gtatatagga atgataatca tatcgtgagc tttataccat
    12721 tttggattat acctgccata acgttttaaa agtgttatgg ataaatctgc tttactcgct
    12781 ggtctccaat ctcttctcag cctgttgtat aaagattttg taaggtgttg actcatatgg
    12841 gctaaatctc tgtttacgtg cgtggctact tcatagtaat tatggattcc cattactacc
    12901 gtattatatt tccacactgc gtcacgtgat tgttcctttg caatcctttt aatagattgt
    12961 tttagtttat catgtgcatg tctgattgcc ttgtcactca tgtgactata agccacataa
    13021 ccatttcttt ttggtcttac atacatagta aaacccagaa attcacttcg ctgttttcta
    13081 agattgacta tttttgattt ttcgggactg atttccaatt tcaatcttct ttcaataaaa
    13141 tcttgcgtag catgatacaa tctcaatgca ctcggataat ctcgacagaa gattttaaaa
    13201 tcatcggcat aacgaaccat atagcaatgt tttagattct tcctttgtct catcaaggct
    13261 cttcttgcac ccttatgtgt tgtatattct cttatagttt tgattgtttc ccactgattg
    13321 ctaatccacc agtcaagttc attcaacaca atatttgcca ataacggact taatataccg
    13381 ccttgcggtg ttccttttat cggcttaccc tctccgataa tttctgcttt taataaagtg
    13441 gaaattatgg aaagcagttt cttttctcgt attcccattg tccacatttg ttttagcaat
    13501 tttccatgat ttacattatc aaaaaatcct ttaatgtcca tatcaacaca ataatggtat
    13561 ccgttccctt tattattcat aaaatgattt gctcttgcta ttgcatgatg agcacttctg
    13621 tttggtcgga atccgtaact gtgtggatga aattttgctt cacatatagg ttctaaaatc
    13681 tgaagaatac attgttggaa taacctgtcc catatagcgg gaatgcctaa cggtcgtttc
    13741 cgtccatcag gtttagggat atacactctt cggacttttt caggttcata ccatttgaac
    13801 atttcccgta tttttgttac aacttcctca actgtcaaat cttcgatgtc agctattgtt
    13861 tttccatcaa caccagcagt atgactgccc atgttcttct ttatattccg ataggctaat
    13921 cggatatttt cttcactttc cataagcttt gtcagcttat aaaagttatt tccattcttg
    13981 ctttgcatat ataattggtc taatttagac tgcatatcat aatactcagc gtaccttagt
    14041 ttgtttgtct ttttaataag ttggctcctc cttaattgag gtttgccctt tttagtctca
    14101 ccagaacctt attctaacaa cttactaaga agaatgaatg atacatcttt catagactag
    14161 tgaccgtccc tccacgtttg ttagacgctt catcagtacc atgtcaccgc tttcactgcc
    14221 ataaataaag ttatacttct gctattttca caaaagattt cctttcaacc acttcataga
    14281 agatattttc tccatgttgg cagcttccaa cgttccatta cttttatctt tacatatact
    14341 tttaggattc tcctttgagc ctgtcagctt gttactgcct ttaacaataa acggattttc
    14401 ataacaacta atcttactcg tccgcactga caccacgcac gtggcataca catttctgtg
    14461 cattagggtt atagacccgt acattcggag attcgtcagg ttcgtctcgc caatagtttt
    14521 gcgaacccat tctatccatg agtattttat agactcccgg tctatgggtg acaccgccca
    14581 cctctgagca gatttcgtag catttgataa tgctttacgg tcactttcaa ccgacttcac
    14641 cgagcttcat acggttcatg ttaatatcaa cttttcccgc atgtcggagt attagaggaa
    14701 accctttgtg gcgttaccca ctcatttgat ttctcaaagt aatagttcta aacagcactt
    14761 gctgtctgcc tagccttttc agctaggaac gtttcacaca attgtagctc tggacaacgg
    14821 tattcatatc acagcctttg ctttgtgcag aagaaagcag ggaagcaaaa tatttgcacc
    14881 cctgcttgat agattcctcc gtccctaatg agttgggcgg taagcccatg ctttctgacg
    14941 actgcataac gtcagtagcc gtccctccgc tttccacctg tataatcgcc atgagataag
    15001 ggacatactc ggaaatgccg tattctttcg catatttttc tacggttggc tgatgtttta
    15061 aaacttccgc tgacaggttc attcccgtaa cgccagaaga atagctgacg cttccgtcgt
    15121 cgtcctcagc actaatcaaa attccaaaga acagcagtat cgcaaagaga atcggaaaaa
    15181 tgctactcac gatagcgata tgctttattc tcatggttta cgtcctttct ttggcgtact
    15241 gccttttgct ggtgtggatt tcttctgtac ctgttttgtc tgctggctct tgacggtacg
    15301 cttattttta acagcctgtc ttgtggtctg ctcccttacg gcagaagatt tttccgacgg
    15361 cttcatgctc ggacgctgta tagtttcctt tggctctggc actttggaaa cagcaccgcc
    15421 tgttacggga cgctctttta ctgtcggcgg tttctctgta tcagcactcg gcgttttaga
    15481 agtgacagga cgtttttctg attttgcgga agctgtgaca ggtctttcat ggggacgggt
    15541 agctcctgct gtcgctgatc cgtccgacct tttcgcagac tgcctttctt cctgtgcttt
    15601 ctgcatagtc attcgcttat ccgcaatact ctgtctgtgc tggttgagct tatccgcacg
    15661 tccagcctgt cggtcttgct gttccttaat cacgccacgc ttgaaatcag acacgttttc
    15721 ttttgctctc tctttggcgg aatgaaccgc atatccagcc tgtgtcggca tatccttgac
    15781 ggattcctta acagcggttg ccttatcacg gatacggttt ttcgtatcta ataccgcacc
    15841 tacggcagag ccagccttac ttcccataga agaagcggta ttgctccttt gtggttttga
    15901 tgtgccagaa cgggaagaac cgctggtgtt agagagcata gaaccagcca ccgcaccagc
    15961 tccagcacca gcaccgacag cccttgcaag ccgtctttcc attcgccttg tcctgtggcg
    16021 tatgaacatc atcggacggc ggaacattct acgccccata ttttggctgt cgctggcatt
    16081 aagggaaaac atactcatca aatcgcccag cttcatatag attcctgcaa aggtcactat
    16141 ctgaagaaac gccaccatga aaaacgggta gtcgtctgac atattgtaga acatactgga
    16201 aatggaaaat gctaccgtca ctatgagcgt gattcctgcc cttgtcatta tggtattgaa
    16261 cacacgcacg attgcctgtt ttgccatgtt ctcataggtc ggtatcatag aaagtaaaaa
    16321 gctgacaggc aggaacatgg cgaaaatgat aaataatatc tgggaaaata tcatcatgcc
    16381 cgtaagcagg aatacgaata ccgttatccc cagattgaag ataagcagga agaacaccat
    16441 tcccagacgg ttcataacct gtggaatcgt cagattgtca ttatcaaagg tttcgatttc
    16501 tgctatgaca acatcttccc ttgtttcccc gtcgtcgtcg gacgggctga cggaaacgag
    16561 agcttccaca cggtcagtcc cgatttcctc cttattggaa tctccaaact gcaacagtag
    16621 ccacggctgt tcgacctgta tcgaaaacag gctgtccctt atcaaatcca cactgtcttt
    16681 tccctcgctg tccgagccag ccagcatgat ttttgttccc aagtcaaggg aagccgtgct
    16741 gatgtcggac gaaaaatcat tgactttttt tatgtagtcg ggagcgtaag cgataaagga
    16801 agccgatacc agaaatatca caagaaaatt cgtgaccgca tgaattgctt ttgtcgtttc
    16861 ccttttgata agccccgtat aggcaacata gattcccaca acgagaataa tcatcaagag
    16921 aaatccgacg tagaatccag aagaagaaaa accgcttttt gttacgccag ctatggtctg
    16981 tatgctcttt ccgatactgt ccgccatatc gttaataaaa tccagcttgt aggcttcctg
    17041 taccacatag cctgtcgcat tgctaaggta caggctgatt atccagacaa aattagtgat
    17101 acagtataag ccgtactgaa cggacttccc gataccgtcc agccagttcc acggaagcca
    17161 cgaccagcta ttatccacat agaagtcaag ctggtaattg gataggggat atttggagta
    17221 cagattttcc gcactgactg tatcgtccac aagtcccgtc gcatgagcca cagtccccaa
    17281 gagcgacagc gtgacaaccg ttgtcgctat gacaatcaca gccaccttga caaaatgaaa
    17341 gagcttcttt ctggtaagaa gcccctgtaa tcgttctttc atttacccca cctcgctttg
    17401 cttcactggc ggtctggtat cgaaagcgtg tagcagttct tcaaagacag ggtgtatctg
    17461 caccacaccg acacgcccgt ataaatcctg caacaagcac tgtccgtttt ccaagtcacg
    17521 caggcgtttc tggttgttct cgtcctcctt gtcaatcccg aaaaattcca atgtctgctt
    17581 aatctcgttt atatctgtac tacggaaagc aaacttcaaa ccgatattgt ttttcagact
    17641 ttcctttgat acgtccccag agctttgcgt cacaaagtac acgccagcct gcatagcacg
    17701 tccagcacgc accagcttgt ttgacagtgt ttcgccctgt gccacattta agaacgccca
    17761 cgcttcgtca aggtcaacga ttttgaaaat gctcctgtct gaatgaataa aatccaatgc
    17821 aaaggtactg ataacgatta gcattgacac ggacaaaagc tcaatcgttg tgtattcctc
    17881 aaaggtcgtg tccttatcgg gcaatacaag gtctgccacc tgtataatat tgagctggtt
    17941 gtcaaggctg attgcatttt ctacgttgcc gtccgaaaac agcagatgtg caaagtcata
    18001 gtccgtaaag ctgtcgatat ggtcggctat attgcgtgag ataggcgtat cttccttgcg
    18061 tagctcgtct atcacatgga gcaagcccct tgtcggactt tgagccacgg aacggacagc
    18121 ctttctaagt acggggaatt tttcgccgtc cctagaggaa attcctgtaa ggaatgtaag
    18181 tatgtcaatc gccagacttt cagcgtcctt gacattcttc ataatcacga acgggtctaa
    18241 cagtccttta ttcatggaat cgctggtaag gttgacaatg tttatctcat gggcgatttc
    18301 tggaagcgtt tctttccagc tcccacgctc actttttggg tctaatatga ctgcctgtcc
    18361 tccaaacagc acggaataat agacaatcag attgttgcag aacgatttcc caccgccaag
    18421 cgaaccgaca aaggcagaag ctagggcatt ggtaacagtc cccttgatac cctgtgaagc
    18481 aagggacggt tgcagataga cattgcgtcc cgtatcaacg gaatagccga tatagatacc
    18541 tgtgttttcc cctaactgct gtgtcgcccc aaaaccaagc ccagccagaa agtccgattt
    18601 cacatactgt acatagtcat tgatgtaacg cctactggct ggaagaaatt cagaatgaag
    18661 tcccagcata tccccagcag gacgcaccag cttgacgttc aaatcgtcgt aaaagtccct
    18721 gacttcatca caacggcgtt tcagctcgtc aagatcgggt gctgacaccc gtatgacgta
    18781 gcttaacttg tacatacttt cctttgtctg gtcgaggtca gcttccagct cgtccacgct
    18841 gtctaatgca tccaccacat ttgagctggt ttcgctcccc gactgatagg cgtgattgtc
    18901 caagtctttc agctcctttt tcttgtttct gaccgttgag agagcttttc ggttttccac
    18961 gatttctaca ttcatggacg tatcaatcgg gaacgtaaac tgctgttgct ggaaatagaa
    19021 gatttccgac gacgggaagt ccagctcccc gacaatcgca ttgaccgtaa aatacgacac
    19081 atagctttcc gtgtcctcat gctccaagcg gatatatcgc tggctttctt cgataaggca
    19141 acgggtagga cgtaccaagt cataatactt gataagcgtt tctttcttca ttttcctttt
    19201 aggtaaggaa tactcataat cttcataagc cacgccgtcc ctcccgtaga tatgctctat
    19261 cagatacccg aaatcgttct tttccagacg gcgtatcttg aagcgacggg aaatcttgtt
    19321 ttccaacagc ttttccattt tcatgtagcg gttgatttca tcattgctta tggaaacaaa
    19381 atcattcatc agcgtgtggt tgacttcccc aataaactcc ttaaatgtca gaaaggcaga
    19441 ttgcttcata ctgtcaagac tgacattctg ctccgtaacc atgagcttaa agccaagaaa
    19501 aaagcggtaa tccacttgat tatcgccaat catggaaacg agggcttccg tctgttcatc
    19561 aattttctgt actgccacgt cacgcaggcg tcccgtaacc agcttctttg actgttcctg
    19621 tatgcttctt atggagcttt ccgtcgctat ctgcaaagca tggatttttc cctctctatt
    19681 ctgggcgata agctgacgga agttgtcatg cacaatgaat ttctgttccg ctgataaaaa
    19741 gctgtaattg taggggataa gctcatagta ggcgaacact tcgccgtccc tgttccagac
    19801 aaggttgttg tcaatatatt ttatgtggaa catacatcac actcctaact gccgtgatag
    19861 tttcattgaa tttctgctta tgcagtttca cggcttttcc tgcataagtg atttttggtc
    19921 taagtgcata ggttatctgg gattttagga agctgtaagg cttcttgccg tcaaaggtct
    19981 tttgtgacat aaaccatgta agggcaacgg gaatcccaaa gtatttcaaa aatgccccgt
    20041 caatcatgga taacggcggt aagtccccaa acagaatgat gataaattct gtaatgacaa
    20101 accacgttat ttgggtaaag gtaacgggaa acgggaggtt gaagtcattg attgcataca
    20161 aaactttttc cacgttccag atacccgtat agcttttgat ttttttcatg tacctgtatc
    20221 aatcctttcc tagagtaata cggacagtca gcaggtctgg ccgactgccc gtttcatgta
    20281 aaaagctgtc agtagaaccc gtacaggttc agatctgaca gcttatcttt gaatctcaca
    20341 cataccgtag ctggtttcga taaaatagcc ctcgatttcc aagtcacgtc cgtaggcttc
    20401 atagtcaatg taatattcca agctgggcgg tatatcccca agcgtatgca gttcgtccac
    20461 atagtagcgt gcgacatctt ccatgctgtc gcagtcggga tagaaatata tctggtcttt
    20521 atgttctaca acaccctcaa ggcttccata gtaagagata aagtcgtcca gactgtcaac
    20581 gacttcttct ggaagttcct ctatcatttc atacatacgg ttgagttcat caatcgaaat
    20641 atattcagat acttcacagg ggaagttgtc tgtatcatgg acggcatatt cttcatattc
    20701 gccatttaat ccgatacgct ccttgatttc ctcatagtcc agaggaaaag agaaccagtc
    20761 gcccaccaag taaccctcgt tgtatttgcc gagattcgca atatataccc tcatatcgtc
    20821 taccataggc aaacacctct tttacggtaa ttcatagata ccgtggtcgg tttcaacaaa
    20881 tgtcccgttg tcgtcaaggt actgtccgta ggcttcaaaa tcaaagtagc gtacacaatc
    20941 ctctgataat gaggtaaacg ctggattttc agccagacag cgacgggcaa tgtccgtcat
    21001 gctgttgcag tcgggataat ggataatgtc atagcggtgc tggtgcaact cgtccagact
    21061 ggaaaaatgg cacataagct cgctgtattc gtcctgcaat tctgacggta aattctcgta
    21121 catatcgcat aagtcattca atcgctcaac gggcgtatct tcgcccacat catcagcaaa
    21181 cggcacgtct ttttctatga tacggtaagc gtcggaatcc gcttctatgc cgagggtttc
    21241 ttcgagttct tcttcatcaa tgggaagcgt aaaccatgca gaacgtcttt cactgtctgc
    21301 tgactgtttc gcttcaatca atactcttaa ttcattcaat cgttttcacg tcctttctct
    21361 gtaaaacctg tgctatgacg gtgtacggga caccaaatac atagcgtgaa aaatcttcta
    21421 actgctgtcg gggatagtcg gcaagggata agagtttcac ttcaaaccag accgcacgct
    21481 tgcagtaggg caaatcggaa atgtagcgac accctgtttt tgccagcata tccgaaaaaa
    21541 tatctttgtg tatcattcct tgacctcctt tcttccccct atgtccgaag tcccacaggg
    21601 ggaaaggcag gtttgcgtat cacgcaaacg ctggattcta agcaccaata atcttattga
    21661 atagctgtaa cagtacgtct ttgacaccgc cagcattgaa tacaagaccg acagagatta
    21721 aggcaaccac caagaagcca atgagctttg aaaactcacg cttgaaacct aagtagatac
    21781 cgattaccac gattgccatt agcactaagc tctgtgcatt tgataaaaac caagtgtata
    21841 aattctgtcc gaaattcatt tgtcattcct ccaatcattt attttttcca ttcttttgtc
    21901 agcttccttt cctgcctgca acaagcacat gaggacaact ccgaagattg ccccagaaga
    21961 aaagagcaga aatttactca acacgttcca catataaaat tcctcctttt ttatttcagc
    22021 acgatttcct ctgtggaagt cgtctgttgt ttgatgattt tttcgtgctt ctccgaaagt
    22081 ttcgcctgtt cctcgatatg cttcaaaaaa tccgtaccgt ttccagcgtc tatctttttc
    22141 agcattttca aggtcggggc gacctgtctt gctatccagc tcattgtcct ttcaagcgta
    22201 tagggttctg gctgtgtcgt cagcttcaac ggaggtctgt cctttccgat aaaccaagac
    22261 cagcggtcat tgagcttcca ttggttctga cttttgccag cttccttgtc aacgaatttg
    22321 atatagcggt taataatgga aaatgccgtc tgttcagcgt catacgttgt cagcaaatca
    22381 cggacggcat aataggcacg ctcatttttg agtcgtatct caaaacggtt ctttatgggg
    22441 gattcctcaa tcgggattcc cagcttgaca tactgctcgt agttcttttc ataacagcag
    22501 aagtacacct cgcttttcag agaaccgata tacagcgtgt gtcccattcc tgccttgtcc
    22561 tgttcgtcgt gcttgacaaa ctcgcccgaa gcataagact tgaagctacg gaacagggaa
    22621 acacattcac ggtatttgca tttttccata agctctggaa tatccagaat acccgttctg
    22681 tcatttatcg ctaagtcgat acgcttcatc acaccgccct ctatgagagc gtccatgaaa
    22741 aagtcatacc agcttcgctc ctgtgccagc agatagcttt caaactggcg acagcctttg
    22801 ccctttaatt ccagaagcac gcctttttcc tgctcctgtg aagcatagac gaacacgtcc
    22861 ccgatatagt aatgctcggc gtaggtgtaa tgcccgtaat cttcatggag catatatttg
    22921 atgttcagct tcaaaatgtc atgtataacg tgctgaacat ctgtggtagg aaaacggatt
    22981 ctcacatagt caaacagcat agttaaggga ttgtctggat tgaatttttc cagagcttcc
    23041 atgagcttgt ccctcacttc ctttgacggt ctgactttcc ccatttccat gcggtttagg
    23101 tactcacggc tgataccagc catgattgca agcctgcttt gcgatacccc aaaggacaac
    23161 cgcttttcct ttagggcgtt tatccagtca ttctcattca gttgttatcc ctccaatcgc
    23221 agattgtgaa atttttaaac acaggtcaca atcagaagaa tttatcaaaa atccttgtac
    23281 cttgcggatt tggtgatgtt tttttgactg tttcctgttg atttgtgccc ctctgttaga
    23341 taatgagggg cttgtttctg ctggcgtggc tgacgccaca ccagcaacgg ctagtccgtg
    23401 ccgtcgcctt tcgcttcgca cgtcgccgtc ccgtcctgcc ttgcatatgc aagagaacct
    23461 atggtctgca aaaaatcata tcctttcggg actaaaggcg tgtaaaattc acttatgatg
    23521 cttgttccca catcacaata gccacgccct ttgatacgct tctggaaaaa ctgttttttc
    23581 acatcagaac caaacagcat accgtaacct aattcgctga tacgtcccaa ccctacacgg
    23641 aaattgaagt tatctctgat accgtccgag aaatattttg cgtctggtcg ctggcaggca
    23701 acgataagga aataccctgc ttgtcgcccc agcatgacga ttttctttaa ctggctaagt
    23761 aaactcacgc tttcctttgt ccccagcatt tcaaaaaacg ccacatattc atcaaagatt
    23821 aaaaagcagg gcggtaagct aagataggcg tagttttctc ccgttttata gttcgggtgt
    23881 tgcttcattt cttcgcttcg ttgtaccatg ccctcataaa aggcattgac gcaatcaatc
    23941 atttcttctt tagtgtgata cacgtttccc atgactgttc ccaaatctgc aaggtcagcg
    24001 ttctttgggt ctaagatgta aaggacagcg ttggtatgca gtagggcttc aatgagcgtc
    24061 agaagaaaat aggttttacc gccaccagtc ccaccagcaa tcagagcgtg agggagtgcg
    24121 tcatattccc agacaagatt tttcatcagt ctaagacagc cgttttctgc ctgtacttca
    24181 tcaatagtaa tgcggtttgc tatcatgtca taaagcaggg
//
LOCUS       DAEOTL010000055        24019 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEOTL010000055 DAEOTL010000000
VERSION     DAEOTL010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24019
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.055"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     regulatory      240..341
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            414..1757
                     /locus_tag="KRH82_002595"
     CDS             414..1757
                     /locus_tag="KRH82_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBG8655866.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            1935..3299
                     /locus_tag="KRH82_002596"
     CDS             1935..3299
                     /locus_tag="KRH82_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8655867.1"
                     /translation="MSQLLIKNAYLITMNADREVYETGSILIENNIIKNVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHNPAAAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(3477..5342)
                     /locus_tag="KRH82_002597"
     CDS             complement(3477..5342)
                     /locus_tag="KRH82_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBG8655868.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWYISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(5578..6795)
                     /locus_tag="KRH82_002598"
     CDS             complement(5578..6795)
                     /locus_tag="KRH82_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8655869.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVIDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(6995..7858)
                     /gene="aroE"
                     /locus_tag="KRH82_002599"
     CDS             complement(6995..7858)
                     /gene="aroE"
                     /locus_tag="KRH82_002599"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBG8655870.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(7940..9862)
                     /locus_tag="KRH82_002600"
     CDS             complement(7940..9862)
                     /locus_tag="KRH82_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBG8655871.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(9956..10804)
                     /locus_tag="KRH82_002601"
     CDS             complement(9956..10804)
                     /locus_tag="KRH82_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBG8655872.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            11216..12097
                     /locus_tag="KRH82_002602"
     CDS             11216..12097
                     /locus_tag="KRH82_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8655873.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(12305..13168)
                     /locus_tag="KRH82_002603"
     CDS             complement(12305..13168)
                     /locus_tag="KRH82_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBG8655874.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(13323..15257)
                     /locus_tag="KRH82_002604"
     CDS             complement(13323..15257)
                     /locus_tag="KRH82_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBG8655875.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(15369..16382)
                     /gene="galE"
                     /locus_tag="KRH82_002605"
     CDS             complement(15369..16382)
                     /gene="galE"
                     /locus_tag="KRH82_002605"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBG8655876.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(16406..17275)
                     /gene="galU"
                     /locus_tag="KRH82_002606"
     CDS             complement(16406..17275)
                     /gene="galU"
                     /locus_tag="KRH82_002606"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBG8655877.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(17473..17793)
                     /locus_tag="KRH82_002607"
     CDS             complement(17473..17793)
                     /locus_tag="KRH82_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655878.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(17783..19774)
                     /locus_tag="KRH82_002608"
     CDS             complement(17783..19774)
                     /locus_tag="KRH82_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655879.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(19897..22440)
                     /locus_tag="KRH82_002609"
     CDS             complement(19897..22440)
                     /locus_tag="KRH82_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBG8655880.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEEIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEMEQNEL
                     KEIKQKEPSQHIEEERNVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(22718..23052)
                     /gene="rnpB"
                     /locus_tag="KRH82_002610"
     ncRNA           complement(22718..23052)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRH82_002610"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            23184..23861
                     /gene="srtB"
                     /locus_tag="KRH82_002611"
     CDS             23184..23861
                     /gene="srtB"
                     /locus_tag="KRH82_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBG8655881.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNSESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
BASE COUNT         7687 a         4142 c         2689 g         9501 t
ORIGIN      
        1 ttacgaaata tccatgtatt cagtactttt ataattatat cacaaactca tttataataa
       61 acttccatta atagtataaa acaagttaga ataattgaca ttatactcat acatattcaa
      121 ttattggaaa aagtaatttt tttcaataaa taaccttaat tttttataaa atcgacaaaa
      181 aaacgaataa ttttattata tttattgtaa ataatacaat attacgatat aatacaacag
      241 aaaaacaaat agaaaatgtt catataatat tagtaatacg gtctaatagt ttctacaaac
      301 tcaccttaaa tgggttttct atgaatagaa tgtcaactct gaatatatgt tctattctat
      361 ctatatgaat atatattttt ttgtttatat cttaaagttt tttggaggta aaaatggtac
      421 caaacactaa caatgtacaa ccaggtggaa ataattcatc attaagcttt ttagacaaaa
      481 tgtttaaatt tagcgaacgt ggctctagcc ttaaaacaga agtaataggt ggagttacta
      541 cattcttaac aatggcatac atagttttcg taaatccagc aatattatct gaagctggaa
      601 tggataaagc cgcccttata acagttacca tactagctac agccattggt acacttatat
      661 ttgcgatttt aggaaatgca ccatttgctc tagctcctgg tatgggatta aatgcatttt
      721 tcacatactc tttggttata ggtgcaggaa tcccatggca aacaggtctt ggggtagttt
      781 ttctatctgg atgtgtcttc tttacactcg cagtaacagg tcttcgaaag acaattgcag
      841 acgcaattcc tagagaattg gcagtagcat cttcagcagg tataggtctt ttccttgctt
      901 ttgttggttt aaaaaatatg ggtgttataa tagctaatcc agatactata gtttcacttg
      961 cagattttac accaacagtt ttaatagccc tttttgctct tatcttaatg gcaatactag
     1021 aatataaaaa agttaaaggt ggaatattga taagtatagt agttgcaaca ataatatctg
     1081 ttatatttgg atttgtggag ttgccaacag caataatctc aacacctcct agtatagcac
     1141 cagttgcttt taaattagat attgtaggtg cattgaaatt ctcattaatt ggacctatat
     1201 tctctttcat gtttatagac atgtttgatt cattagcatt tcttattact tgttgtaaac
     1261 aaatgggtct tgaagatgag aatggtgaaa taaaagattt aggaagaatg ttatatgcag
     1321 atgtttcttc tactttaata ggctcattct taggaactag tactgttaca acatttggag
     1381 aatctgcttc tggtattgca gcaggtgcaa gaacaggact tgcttcaata gtaacagcag
     1441 cattattctt agctacactt atatttacac cattacttgg tatagttcct acttacgctg
     1501 cagctcctgc acttgtaatg gttggtgtat tcatgtttga aagcataaaa cagattgatt
     1561 ttgctgatag caaaatagct gtacctgctt ttgttacagt tttattgatg cctttaactt
     1621 atagtataag tattggttta tgctttggat ttatttcata tataataatg catgtggtag
     1681 ctaaagaaac tgataaaatc agtattacac tttggattat aggtttactt gcagttgtaa
     1741 acttagttct aagttaatat tttaaatagt tctaggtcaa tattttaaat tatatagaat
     1801 aaaatcttat ttattttaaa tttataaata gcaaaatcaa tttatgtata aattgatttt
     1861 gctattaact ttgtatagaa aatttattat cataatacat agatataaaa atatatagaa
     1921 aagaggttgt acttatgtca caattactta taaaaaatgc atatctaatt actatgaatg
     1981 cagatagaga ggtatatgaa actggaagta tacttattga aaataatatt ataaaaaatg
     2041 ttggtaagtt tgatattaat attgtagata aagacgctga gatatatgat gctaaaggaa
     2101 aaatactaat gccagggtta gtcaatacac acgttcactt atcccaacaa ttaggacgtg
     2161 gtcttgcaga tgatgttgta cttttaactt ggcttagaga gagaatctgg ccatacgaaa
     2221 gtagcttcaa ctatgaagat tcattgattt catctactgc atgttgtgtt gaattgataa
     2281 aatctggggt cactacattt ttagaatctg gtggtcaata tgtagatgct atggttgaag
     2341 ctgttgataa aactggactt agagcctgtt tagctaaatc agttatggat acaggagatg
     2401 gtcttcctga agcatggcaa aaaactactg atgaggaaat caacactcaa ttagacttat
     2461 tccataagtt taataacaca tctaatgaga ggattaaaat atggtttgca ttaagaacta
     2521 tttttaatac aactgaagaa ttacttgtta gaactaaaga attagctgat aaatacaata
     2581 caggtataca tatgcatatt gctgaaatag ctgatgaaat ttcatttgta aagcaaaaca
     2641 atggagttgg aacagttgaa tatcttgata aactaggtgt attaggacca aatcttttag
     2701 ctgctcacac agtttggctt actcataaag aaattgattt atttagatta catgatgtaa
     2761 aagtttctca taatccagct gcagccatga aagtagttct aggatttgca tcaattcctg
     2821 aaatgttaga aaaaggaata cctgtttcaa ttggtactga tggagctcct tcaaataata
     2881 gaatggacct tatgagggac atgtatctta catcactaat acataaagga agaactttaa
     2941 acccaactgt cgtaccagct gaagaagtct tagaaatggc tactataaat ggagcaaaat
     3001 gtgctttact agaaaaagaa attggtagtc ttgaagtagg aaaaaaagct gatatgatta
     3061 ttctaaatcc agatacaatt cattgtttac caatgcataa tccaattgga aatatagttt
     3121 attctatgac tagtgaaaat gtagactcta ctatttgtga tggtaaatgg ttaatgaagg
     3181 aaagaaaagt attagttgta gatgaatctg aattattaaa taaagttaaa aaacaagctt
     3241 ctaaaataaa agataaagca gaagttaaaa ttccatctaa atttaaaatt ataaaataac
     3301 ataaatttca attgttttgt aaatatgaat atataaatat atttatatac atcatatata
     3361 caaaacaatt gtttttttat tttatattca ttagcattgc tcataaaata caccataatt
     3421 ccagaaaaaa taaccaatca gttaagatta catcatctaa gcaatatata aacgtcttag
     3481 tttataagtt ttattctact cttatctaaa accatcttta aagagttttc aactgtttca
     3541 attacatctt tataactcaa gtacacattt gcgtagatac aatcttcata taaattatat
     3601 tcagttactc tacaatacag cagttttcct ccatctaata aattgctcaa aatatagttt
     3661 tcttttcttg ggacatagcc tattacatat ccagtttcac caactatttt aatagctttt
     3721 tcatcatata gattatcttt ctctctagtt aaatagtata tcttactttt ctccaattct
     3781 ttttcaagat attctctatt tctaaacctt gaaccagcaa cagctattga agtcaaatag
     3841 atatccttac catgttcatc tacttttatt ttttcaatat ttacaaattc tttttttaaa
     3901 ttattacttt catataatac tcttcttaat tcatccttca atataacatt tttttctttt
     3961 tcatacgctt ctttaacaat ttttaattct tcaagagata gtttctctct gtatcttttt
     4021 aagatattta tggattcttt tcttacttca tttatatttc caaatattcc ttttaaagat
     4081 atattctttc cttcaggata tagtgattta cttcctttaa gcacaataaa aaataacata
     4141 tcatcataat attcttgagt caatttatct ttttctatat ctttcatttt tccaattaaa
     4201 tcatctattt taaacgtctc ttcaaaaaaa tttaataatt ttaatctaga acttgttgtt
     4261 ccctttttag atatatacca atatacctca aaatctctaa tatctctatt cagatatggc
     4321 aacaagtcat caaaagataa gtttacatca taaatttctg acatttttat aatatcttct
     4381 gtttttccac tagcatctct taatgcttca aaatatatat ttttccattt ttcactgagc
     4441 aagataccat ttatttcttt ttcaaattca atcttattgc actctatatt ttcatctttt
     4501 aagacgttta tagctattag gaaaattgaa tataaacttt caaagttagt cccataattt
     4561 actacagtag gtaaaaatcg attcactaat tctaatttat tacctatata tttaaattct
     4621 acacttagca agtaattgca tataagacgt gctaaattat ttatcttttc tttatctaaa
     4681 tctcgttttt caagatattc attcaaatct acaattgaaa taatatagtt catcaataat
     4741 cgttcgtact ttgtatcctt ataaccatct tcaattagat aggaatttat tttagaatct
     4801 aaattttcca tattaacaat agcaaatact tttattgaac ctgtagcctt tttagataaa
     4861 ttaaataaat atgtattgta aaattcaagt tttttaatag tattactcag ataaaatacg
     4921 tattctccag atttagaaaa tgtatctaca acttctctta agttttctac atttagatat
     4981 ttctcactta aaactaaccc tagttttaca tactcaactt ttttactctt atatattaat
     5041 tctttagtta atttatataa ccatttctca tcaataatca tttcttttac caaagtattt
     5101 atctttttca taaaaatttc gaaataacaa attaaagact tagaattact atcctccaat
     5161 aaataaattt cattagattc acttttatac atatttaaaa tttcatctac tagattattt
     5221 gcaagctcta cttgttctct taacggtata ctttcatata tacataggta attcatttca
     5281 aatgattctt tgtatccatc ataaccatta aattcctgca atcgcttaaa aacattctcc
     5341 accaaattat cctcctttac atgatgtaat ttatattgat tatactactt atttcgtcaa
     5401 gtttacattt atacgcaaaa aaatattact agaaattgaa attctagtaa tatccttatt
     5461 attaattatg taaataccct atcttataac tgtaaataat atccttatta attttaatta
     5521 cttttaataa aaatctatcc tagatttaga cttctctatg cgtatattat actaatatta
     5581 gacatcataa tcatacactt tttctttttc atatctcatg tttacaaaca atgcaagtaa
     5641 aattccaaca aatgttattg ccacattaaa caatacaaca tattttggtc cattaactcc
     5701 ccctgatttt gtaataatac ctgctatatt taaaataaca tagtttgcta tactagatgc
     5761 aatcataact atagatgtta tttttccttt attagttgga aacatttcat ttgcagttga
     5821 cgttgttaac tgaagaacac ctcctgctgc tgaataacct attacaaatc cccctaacat
     5881 acaaatagtt ggagtttgaa caaaatatac aactaatagc ataagtaaag ctattatagg
     5941 atatataact aatattctta ttggtttaat atatttttta ataagtaaag aagttattaa
     6001 tactgcacat attactccca ttgagtaaaa ggattgaatt tttgtagggt cagccatccc
     6061 atacaattta cccaattcct gattacaatt taaccataat acaaatgtag atgtacatgt
     6121 aaatccaata caaacaagag ctatacttgt tggtgtaaat ttcatcttct ctgatttaac
     6181 tgttttgcct ttgttatcaa taacattatt agctggtgga aatggtaaca cagctatcaa
     6241 aattgcatct attacaataa gaatcgctgt tactataaaa ataactttaa atgatattga
     6301 atttgctgca acaaatccaa ttataaaagg aagcaaaaat tgtgctaaag ctattgtaaa
     6361 tttagtaaac atatttgcta ttgttcctaa actagcaaat atctccatac aagaaggagt
     6421 tacacaggta tctaagaatg aatttgctgc ccctccaatt attgcaaata catatgctat
     6481 ataaaaattt ggtgaaaata caattccaac aaagaaaatt gcatgtagaa agtttcctat
     6541 aagaccactt acttttcttc catacttatc tgaaataggt cctgcaaatg gataagatat
     6601 aagtctccct aatcctagtg cagcaataac agctaaaaca atacttacat ccaatgttcc
     6661 atctgataat gttttagccc cccacattga tgaaaattct ggtttgtatt gtcctaaaat
     6721 tgaaattcca ataccaagta aaaaatatga aaaatacaac gctatggcag taggataata
     6781 ttttttattg ttcataattt ttctcccatt cttgttaatt tattaacatt tttgtgtaca
     6841 ataaactcat ccccataatg gatttaaagt atagtcagtt aaagcttcaa atttaactgg
     6901 actatgaggc aaaacccact atgacaattt gtaatttatt attaaaaata ttgaaatacg
     6961 tatgtttttt cattgtttaa gatattactc ttatctattt aaagcataat tcattaactt
     7021 cttctacagg catttctaat ccagtatata gattaaaagc ctctgctcct tggtataata
     7081 acattcctaa tccaccaata gccttacatc cattagcttc agcatcttca atcatttttg
     7141 ttttcttagg attataaacg acatctgtta ctactaagtc ttttcttaaa acactagtat
     7201 cttttatatt tgtttcattg tcatagggct tcataccaat aagagttgca tttgtcaata
     7261 tatcacttga ttgtatctcc tcataaagtt tgtttgtatc ttctaaatca tatagattaa
     7321 caacacattc tggtacatct ttttttatat tctcaactgt ttgctctgct cttttataaa
     7381 aatcatcctt aggattaaag atagatattt ctcttgctcc atctaaagca cattgtactt
     7441 gtatagcagt tgctgcacca ccagcaccca taattgtaat ctttttacct ttaacttcta
     7501 ccccattttc ttttaaatta cgaacatagc ctactccatc tgttatatga ccaactaact
     7561 ttccattgtc atttacaatt gtattacatg ctccaattat acgagctgct ggagaaagtt
     7621 catccatata ttctgtaaca gcagatttgc atggcatagt aacattggct ccttttatat
     7681 taaaagtttt tattgctaaa agtgcctctt ttaccttatc tactgtgata tcaaaggcta
     7741 aatatctata atctaaatct aatttcttaa aactataatt atacatcact ggtgatttag
     7801 agtgaccaac cggtgtacct attaatgcaa ataatcctgt tctacctgaa atttccataa
     7861 ctataatctc ctcccaatat tatcattttc tttgcaaata gcctattcag ttatttacaa
     7921 agaaaaattt atttattatt tatatattta atgctacttc aaaagcttct tttgttgcat
     7981 ctaatgccct acgagctttt actgcatcac caacaatata agtttctttt acaacttctt
     8041 ttataacttc acttaatggg tcgtaattac gagaacccat agcaagtact actgaatcaa
     8101 aaccttttaa atcatgctct gtgccatctg taagtaaata gtcgacacca tcatcataaa
     8161 atttagaaac ttttgcacca gtaatggtat gtatattata attttcaaaa tcattcataa
     8221 ggaatttacg gtgttctgaa attacatctg caccaacttc ttctctaagc tcaataacag
     8281 taacctcatg ttcttgttct ccaaggaagg ctgccacttc acatccaacc attccacctc
     8341 caacaacaag tacttttttc ccacaagatt ttttaccatc aagaaggtct acagcatgaa
     8401 ttaatcctga atcattgatt cctggtatag gaagtacaag tggagttgct ccagtagcta
     8461 taataactac atcaggtgat ttctctttta taagttctac tgtagcttct gtattagtac
     8521 atatttttac accatattga ttacattttg aaatataact tctaactaag ttagtaatat
     8581 ctccttttcc tggaggatat gcagctaaac gcatttgccc accaagaact tcagattttt
     8641 caactaaagt tacattatgt cctcttttag cacataccca tgctgcaagc atacctccaa
     8701 cacctccacc aacaacaaga acttctttgc taatttcagc tggcttaagc tctgcttcat
     8761 gtcctaatat aggatttgca agacaggcta taggtttgcc ctggaacata tttggtacac
     8821 atccttgtaa gcatgcaata catggtatca tttcgtctag ttttccattt ttagctttat
     8881 taggcatttc tgggtcagcc aagctttgtc taccgaatgc tactaaatca catcttcctt
     8941 gtctgaccat taactcagca aactgtggct ctgtataacg tccaactgtt attactggta
     9001 tactaacagc tttttttatt tcagtaacta attctgcact gaatccagca tgtaaagtcg
     9061 taggagccca catatattca tcatgtatat gtatactacg tgaaacatga agtccatcta
     9121 ttccacaatc ttctagatat gctgctatta ctgaactatc gtgtacatca attcctcctg
     9181 gaacatcatc agtgctgttt atacgacata atattgctag agaatttcct acttttttac
     9241 gtatattttc aatgataaga cgaggtaatc tcattctatt ttcaaaacat ccaccaaact
     9301 catctacacg cttatttgtt ctttgtgata taaaactact aaccagatat ccatgagcgc
     9361 agtgaacttc aacagcatct gcaccagctt tttgtgcacg taatgcagca tctccataag
     9421 attctataag ttcatatatt tcttctgttg ttattgctag tggtgtatta cgaccatttg
     9481 atgcaggtat tgcagaagca gcttttaatg gatgtcctgc tactttttca tttccttcag
     9541 aaccagcatg ttgtaattgt atagatacct tcgaacctgc atcatgacaa gcatctatta
     9601 catttttaaa actatctatt gtgctatcat catataaaca aggcttacga ggacctcctt
     9661 ttgctttttt gtctacaaca ctagattcta tagttattaa tccaaaacca cctaaagcac
     9721 gctcaagata ataagcctta gaagtttcac ttaaagtacc atctgtgttt gcaaaattgt
     9781 ttcccatagg gggaactaca aaacgatttg gaactgtcat tgaaccaatt cttataggtg
     9841 taaacataga actaatcttc ataagttttt ccttcctttc aagttttata tttaaaagtt
     9901 ttatatttaa aagttttata ttataatact ctgtatattt ttatattata taagtttatt
     9961 ttggagatac ttcagaccat gctttatcca aaactttttt agttgcatta aatacagttt
    10021 cagcagcagt ggataaccct ttagatatta gagaatcaga tattacttct gcccctatga
    10081 ctcttggtga tatattgtgt tcttttatta ttttcacaaa ttcctctgtg tttccatatc
    10141 cttcacctgg agccaaacgg tcatgtagtg attcatccct aagtttttca taaggagttt
    10201 ctaaaacatc acacacttga attgatacta tcttatctgc tggaacaggt gcaaggtcct
    10261 ctgctgtctg ctttgctcta gcccagtgcc aagtatctaa tataagcatt gcattttcac
    10321 gattacatcc tttcacaaca cgccatgcag tagccaaatc tggtacacca ctatatggca
    10381 taaactcaag acctataata agttcacctg ctctgtcaca taattctccc aatgcagtta
    10441 taatttgttc ttctggtatc atctctaata atccacaatt tatatgttta acattaaata
    10501 agtgagccat atgataaaca ttttgctctt tttctctttg agcttccgtt ctatcttctt
    10561 ctcttcccca ttgagttata tattctactt ctgtaacttt catatcatat tcattaagaa
    10621 ttgcaatcat ttcttcatct gtaacacctg cattttttgc atcaatataa ttttcagcac
    10681 gcaatccaat accatcaaac ccagcttctt ttgcaatacg aactctatca cggaatgaaa
    10741 cttctgttcc caatgtataa gaactaattg taattggaat attaagattt ttttgattat
    10801 tcatagctta aatttgcccc ctttattttc tttataatta atagtatttt tgattttata
    10861 tttttattta tcctactagt agtattattt taccttaaaa ataaaagtat tttttgattt
    10921 ctatttatct agattttata aatttattgt atcacgagac tttactaata acaaattgat
    10981 aatttcctat taattcatag attttgttta tagattttat ttataagata attcttgtat
    11041 ttttctatta ggtcgtataa atatatttat cttataattc agacaaaaaa cgataaattt
    11101 ttttaaaagc ttttattctt actatataat catatataat aaaaatgtaa aaatatctta
    11161 aaggttaact tctacaaata tataaataaa atacctatga aaggatgaac aaaaattgaa
    11221 tttatatcac ttacgctatt ttgttacatt ggcacattta gaacactata caaaagcggc
    11281 agaaaattta tctataacac aaccaagctt aagtcatgct atttctttac tagaaaatga
    11341 acttggggtg gctttatttg aaaaagaagg tagaaatata gtccttacta agtatggaaa
    11401 aatattttta aaagatgtgg aaaaatcatt agaaatttta gattcaagtg taaaatcatt
    11461 aaaaataact ggtactggtg aaggacaaat agacttagct tttcttagaa cacttggtac
    11521 tgattttatc ccagacatag tgcacaaatt tttaaaatct aatcctgcta aatcaataga
    11581 ttttaaattt catactggtg taactactga cattattcaa ggtcttaaag aaagaaaata
    11641 tgatattgca ttttgttcga aacttgaaaa agaaaaggga attgaattta tacctgttgc
    11701 caaacaagat ttagtactaa ttgtaccata tagtcatcca ctagctgcaa aggatactat
    11761 agatttaaaa gaaaccatac cttatcctca aatagtattt aatcagagaa gcggtcttag
    11821 atatataatt gatgatatgt ttaaaaaaat aaatcaacag cctaatatag tctatgaagt
    11881 agaggaagac caagtaattg ctggattagt tgcaaaaaat ttcggaattg ctgtagtccc
    11941 aaatatgaat atgcttagct ttacaaaagt aaaagtaatt cagattattc acccaagttg
    12001 ggaaagaaac ttttacttag catttataaa agatagatat ttgcctcctg caattaaaaa
    12061 ctttaaaaac tttgtcatta aaaacgctca attataattt attaataaag gggttatttt
    12121 taaatatcct cttttattct ttttataaaa taaaaaaatc tatactttta aaagtataga
    12181 ttcctaactg acagtcggca tccgagtctc agtaattatc gttatataac agcaactgga
    12241 ttcagttcct gaataactag gttacttaca ttatatcaga ttttttaaaa tttgtcaatt
    12301 gtatctaacg cattttttca agccatggtc caacaggctc tacaatagga acttctttaa
    12361 atccccaatt tcttatatca ttcacactcg ttggagtata tattttgttt ctgacagatt
    12421 tgaatatttt gtttttttct ccatattgca tacactttgg attagcttct attaaccctc
    12481 ttcttgctct gctaagagga ttacataaaa tatctgctat ttctaaacct tctctatagt
    12541 cagcatcttc ttttttggca attataaaac ccttaacctt atctcttaat tcttcatcta
    12601 tatctaagta tattgttcca ttattaaata catcaaaaaa cgccttttgt acttttaagt
    12661 ttgagacatc atcccttgac tctataacta ttcgtgcaga ttctacagtt tcattattta
    12721 caaatgaata aaaattctga agaacatgta taaaagccac aacatacggt tcctttgaag
    12781 gtgcataata tttctttaat ctagctttat ctactgttac tgatattata gtacactcta
    12841 atctagatag aaataaaggc aactcatcat agaataactt aatctgtgaa tcatcaaact
    12901 tctcaaatgc tcttgatttt cttgatatat ctgtcaaatg tattcctatg ttactggttc
    12961 caaaacaata ctctttaaat gcatccattt ctttcctcaa agaacataca taatcgcctt
    13021 gacttactgc atatttatat tcaaaaatta ctcctgtcaa tgtaaatggg tcttcatgat
    13081 ttatatcagc tcttccactt tcatcaataa acattatata ttttttcttt ataatcttac
    13141 tcaccctctt aacatatgat gatagcatct atattcattt tatatgagtt ttaaaaatat
    13201 tccaagattt ttatataact taaacttaat tttatactaa aaaattgaga tgtaaaacaa
    13261 tcaagctttt attgattgaa tttcacatct caattataat tatttttcaa tatatatttt
    13321 tactattttg caagaatatc cattaattta tccattacta tataagatac tccgcctcct
    13381 atttgataag gagtttcaac ttttttattt gcaaatactc tttgttgctc tgatgataat
    13441 cctgaattat ccattaaaac tattggtgaa tgtaatttta cagctaatgg tccagctgat
    13501 aaagcatcta ctaaagcatc tgatttacta actaatacag cctgtaaatc agtatctcca
    13561 tagaattttt ctattacttt ggcattagta tctactctac tatctccata tattctattt
    13621 cctgaaatat cttcagtagt tatatcattc atttttgcta ttactgaatc gttaattgca
    13681 cttggtccac ctataaagta tgcattttct aattttcttt ctgttagcca tttataagat
    13741 tcttctgtaa ttccatcttt attgactaat attataggtt gtttttcttc cccagcttta
    13801 gaagctacag ataaagcatc tgcctcccca tttccagaaa ccatatatgc agtttttatt
    13861 tcttctcgat ttccaagttc ttcagctatt cttgtagcag tttgatatct atcttgacct
    13921 gctattctct ttgtttctgt gttgaaagta gtttttattt cttgctctaa tttagaactt
    13981 attgcatttt ctccacctat caagattact gttttaggtg ctaataactt catttcttca
    14041 acagtttcag ttggtaaatt agctgtatta gtaagtagta ttgttgagtc atagctactt
    14101 gctaaaggag ttgctgttat accatcagct attgcattac catttactaa tattacagta
    14161 tctgagctat cagcattcca gtttccaact gaacttatct ttttagctgt atcaaatcta
    14221 tttgcaccta taattgtatc ccatgtagga tttatagttc catcttcatt aaaagtataa
    14281 tctttcccat ctattttttg agaaccagtt agcatctttc catctttgtc taaatagtaa
    14341 gacttaccat ctatttgttg ccatcctgtc tgcattattc ctgttttgtc aaagtaatac
    14401 ttattaccat ctatttcttg ccatcctgtt actgctaaac catcagatcc tagatagtat
    14461 ttctttccat tcttttcttg ccatcctgtt tgcattactc catctgagtt aaagtaataa
    14521 gtttttccgt ctattacttt ccatccagat actcttgctc catcagttcc taaataatat
    14581 tttttgttat taattgtttt ccatcctgtt tgcattactc ctgaagcatc aaagtaatac
    14641 atttttccat ttacttttag ccaactattc ttttggtatg ttccatcaga ttttacataa
    14701 tacttcttac cattttctgt tttccatcct gtttgattta gatttatctt atattttgcc
    14761 gctatcttta catagctgtc gttactataa tctataatta catctgaacc tacaggaact
    14821 tggtcaaata accatctaac atctttattg tgcattctta tacatccacc agaaatatgc
    14881 tttcctatag aactctcatt attatttcca tgtattccat atgtatctcc ataagttcct
    14941 tttaatgcta atcccatcca tctatctcct aatggatttc ttggacttcc tccaggtata
    15001 ttacctttat aatatggtct attttttatc ttgttaacta cttttgtttt ccctgttggt
    15061 gtttctgacc cctttttacc tgttgcaact ctaaattctt ttacaagttt attatttaca
    15121 aaatatccta gagtattttt tcttgaattt actataatca catgtttact ggctgcgctt
    15181 gattctggta cgccacatgc aaatactaaa actaaagtca gtgctagtac taaatacttt
    15241 tttagacttt ttttcactat aacttccccc tcttttagaa acattactac atgtgtctaa
    15301 ttataacata aaattaccaa taccttatat ttacaaattt gttacattta tacatataag
    15361 tatgtattct actcttcata cccattagga ttcatacttt gccatctcca tgaatcttca
    15421 cacatctctt caagttcata cttagctttc catccaagct ctttttctgc ctttgaagaa
    15481 tctgcataac acatggctac atctccagcc cttcttccta caatcttata tggtatttct
    15541 tttccacttg ctttagaaaa tgcttttact aaatcaagaa cactataccc ctttccagtt
    15601 cctaaattat aaacaacaag tcctggattt tcttctaatt tttgtaatgc ttttacatga
    15661 ccagcagcta aatctaatac atgtatatag tctctaactc cagttccatc atgtgttgga
    15721 tagtcattac cataaacact caattccttc aatttaccta ctgctatttt tgttatataa
    15781 ggcattagat tgctcggaac tccatttggt tcttcaccta ttctaccact tttatgagca
    15841 ccgactggat taaagtatct taaaagagct atatccaatg acttatctgc ttttgatata
    15901 tctactaaca tctgctctat cataagttta gttcttccat atggattggt tacagaaagt
    15961 gggaaatcct ctaatatagg acaagtatgt gggtctccat atacagtagc tgaagaacta
    16021 aatacaaact ttttaacacc atattctctc attaattcaa ataaatttaa ggtacttatt
    16081 agattattgc tgtaatattc aattggtttt tctactgatt caccaactgc ttttaaagct
    16141 gcaaagtgta taattgattc aatattattt tctttaaata caacatgcat ttcatcttta
    16201 tttctgatat caatattata aaattttact ggttttttag ataattcctt gattctatca
    16261 accactattg agttgctatt acttaagtta tcaactataa caacttcata acctgattct
    16321 aaaagttcta ttgctgtatg gcttcctata tatcctgctc ctccagctac taaaactgcc
    16381 attgtaatta cctcttttct aatatttatt tttcacttac tttttttctc atatagtcca
    16441 ttaaatcatc ttttaaattt tctctcttta gagcaaagtc tattgttgcc tctaaaaaac
    16501 caatcttatc tcccacatca tatcttctac cttcaaagtt ataagcataa atagcctctt
    16561 gttttccaag agtttgaagt gcatctgtca gttgtatctc tccaccttta ccaggtgtct
    16621 gtttctctaa tatgctaaat attgcaggag ttattatata tcttccaagt atagctatat
    16681 cagatggagc ttcttcaatt gcaggttttt caaccatatc tttaacttta tatactctat
    16741 cttcgatatg ttttacatcc aatataccat atttattagt atcttcttta gctatctttt
    16801 gaacacctaa tacagttgtt ttatactcat tataagtatc tattaattgt tttaagcacg
    16861 gaacatctga atctactata tcatcaccta ataatacggc aaaaggttca tcacctataa
    16921 aactttttgc acagtaaatt gcatgtccaa gaccttttgg ctctttttgt cttatataat
    16981 gaatatttac catatttgat atgtctctta ccatttctaa catctctgtc ttaccttttt
    17041 gctctagttc taactctaat tcaactgatt tatcaaaatg atcttctata gattttttat
    17101 ttctacctgt tattataaga atttcttcaa ttcccgattc tatagcttct tctattatat
    17161 actgtaaagt tggtttatct actataggaa gcatttcttt gggctgtgat tttgttgctg
    17221 gtaaaaatct agttcctagc cctgctgctg gtattattgc ttttttaact gtcatctgca
    17281 ttttttcacc cttcttcgta aattttctat tgtaccaaat taatatacca tatttatact
    17341 ttttcttcaa actctatatt atcccaatat ttaatgctat aagataatat aaggtagatg
    17401 aaatttcatc tacctttagt tttataagtt aatattgtat tgtttatatt ttatccaaaa
    17461 cttatacagg tactaaattt catctaagat gccttttata tcactatcta tatcttcatc
    17521 tagataagaa tctaaatctt ctaagtcaac ttctagttct tgatatgtca tatcaacact
    17581 gacatcctca tctatatcca tttctgatat taattctcct aaaatactat ttccatcaga
    17641 atctaaacca ctatctatat cttcatctat atagttttca tttaaaattt catctaaatc
    17701 aatctcataa taaacttcat tatttttttc atcccctgag tccaatccta agaactcata
    17761 gttaaaagtc caaacattgt atttacttga catactttat tcctcctgtg aaaaacatat
    17821 tttcatctag tttattggtt ccataatcaa cagagttata tattttttca attatgtctt
    17881 ttcttctttc ttttgtacta ttatttaatg tcaattgttt aaatacatat gtatttgtta
    17941 ttctctcgaa taatatttct tttatactat catcatcaat atttctatag tttttccaca
    18001 ataactcaaa taacttaaac atttccctac tagtttcatc tacataataa ggatacatat
    18061 tttctactaa atggtttaat cttgatatgg cttgttttaa aaatacatca agacttgcac
    18121 tttcactttc ttttaacatt ctataattgt atttcttctt atcttctcct gaaattacaa
    18181 agatgatatt gtctaaactt ttttcaactt catttaaata actgcttata ttatatgata
    18241 aatcagacaa tagattttta atctgcttaa acacttgtac atcaagttta gtattatact
    18301 tttcaaacaa atctatttct tgattttcta atattcttgg catatatgct gacaataaat
    18361 ctaaattgtt tctttgttct tgtatttgct tataaagtga atttataact tctattctta
    18421 tttcatcatt taactctttt tctaaaatct tatcaaattc agatttcata tagtaaatat
    18481 ttccaaagaa attaaatatt atcatatcat tcatagcttt agaccaattc ttatatatca
    18541 cttcaataga attttcttta agtagaggtt gctttgcata tataaataca tcttgcataa
    18601 gtttttgaac catactttta cttaagttta aaagtacttt ttgattatta aattttattt
    18661 ccgtttctac aaaattagaa ttttcgtttt caagttcttt attaattaca atgtctttta
    18721 tatcactatt ttttatagat atgatttctt tttgaaaaga ctttagaata gtcaagctat
    18781 cgaaatcttc ttgaataaaa aatggagcat gttttaatgt atatcccact atttcatttt
    18841 ctatatcttt taggtcatct atttgcataa tttctctatt tttatcattt atatgtaggt
    18901 taaatacatt tttattatca tataatatta tatcttctcc taaatttaac ttagaacaat
    18961 tatctttcgc tgactttaca atagtcttct tagatttctt atttataaaa attaattggt
    19021 cttgatattt tactaaaagc atgtttgtgt ttttataatc aaatccatct atatttcctg
    19081 atatcttgca gaatactatt tcacaatctt taggaagatt tcctattttt tggttatctt
    19141 taactctctc atttaaatca gatgggacta cactatctat attgttatta aatatagata
    19201 cagaccttac tataatcccc tctctttcca tatgaaagta tcccttcaat gacactcttt
    19261 tatcttctaa aatgtatctt tctatatcat caaaatttat ttcaaatcta tttttcccac
    19321 tgataaatat aaacttctca ttatctttat taattccacc catataaaac ttattgtcat
    19381 ctaaacttaa tatagtcata ttatccttta gatagaatat aaattctctt tgacttttgc
    19441 agattaaatc atattcatcc aaagttattt tcatagtcaa atttgctgta acatttttac
    19501 ttgaattttc actttttatg taaaaaggca agttatttcc atagacaatt atttgagaat
    19561 cttctaaaac tgcctctaat ttttctttat tgtctgaaaa actatatata tattttacac
    19621 ctgtatcctc attaacttca tctgatttgc tgattattat attccctaga tttgttatat
    19681 gaagcttttt atattctttt gagtatctac ttatgccact aagctcaaac ccatctgaaa
    19741 gctcatatat gattttttct cctaatttca acataccttc accacctaaa cagaattata
    19801 agtattttat aaaggtgaat aaaatgtctc aaaacaaata atattttttt taatactttt
    19861 tattctgaga catagtttct ccttttttat aatgctctaa gcaccttcaa ctatttcttc
    19921 ataaagttta tctaaatgtt taacatattc acgatatcca gatttgttct ttaactcact
    19981 tcttaaatct tcatattttt gtttaagttc ttcagcactc aaagaaggag ctgattcttt
    20041 taattcttct aacttataat catagtactt atcatacata gctatatatg tatcaataga
    20101 cttcttagct agttcattac atttttcttg tgcttctcca tattgagaat aatcacctat
    20161 ttttatttta tagtatccat tttcttgaat tattgttgaa gaaatacctt tagcctcata
    20221 ttcttttgct gtttcttttg ctgttttttc aactttaagt gaacctgcat aaacagtgta
    20281 atatacacct ttaccatctt tatatgcttc catttctttt gctttctttt cagcttgtgc
    20341 tttttcttga gcctcttttt cagcttttgc cttttcttct gcttcttttt tctctttttc
    20401 agcttgtgct tttttctctt cttcagttaa tttattgtta gcttgttgtt gagttgatga
    20461 ctttggaata ttctctttat catttttctt attgttgcct actgttataa aatatcctac
    20521 accaacaata accactataa ctactgctat aatagtttct tttaatctac tcttcttaga
    20581 aacaacctct tcatcatcta aagaatcttc tttatctgat acataatttt tcatttcttt
    20641 cttgttttct ctatatttgt ccttagaaga atttttagat tttttattac tattttcttt
    20701 ctttttaata ggtattacta ctgatttttc attttctaat ttttcttctt ttatctcttt
    20761 tgctttttta tcttctaagt ttttactttc tttttcaagc ttcgattcat tatttgaaga
    20821 tactttttca tctaagttat tatttattgg tttttctatt tttacattac gttcttcttc
    20881 tatatgttga cttggttctt tttgttttat ttcttttaat tcattttgct ccatttcttc
    20941 tgattttact tgatgatttt caactggttt atctaaaatt atatcaggag aaatatcatt
    21001 taaattctct tcttcttgtt caacttcttc attgtctttt ttaataaatc caaataattt
    21061 agccttcttt ttactctttt tattttctgg ttcaattata tcttctttat tgctgtcgta
    21121 ctctttatct gtagtatctt tatcttctac aacgtcacct atatcttgat tattactatc
    21181 tatttcttct ttaacccctt cttcagcatc atcttctatt gaaatactac ttctaaagca
    21241 aatatcttta tctgcatttt ttatcatata aatgtattct tcaatatcga tatctttatt
    21301 tcttctagtt ctttttgatg caatttcatg attttctaat tcactatagt tatcttttat
    21361 tagattctgt gctttattcc atgtatcttc actaatttct gttttatttt taattacata
    21421 gtccacaaat tccttaaaat tttcaggacc aaattctcca attatagtca gtctcattgc
    21481 accttctata aggtctctat ttcttctctt taaaaattct aatacaaccg ttgcacaagc
    21541 aaaatcttta ataatttctt tgccaaaacc atatccttca acagaatgaa gttcttctaa
    21601 tccacataac ttcttatatt cattgtgtat tgtttgagat acactttcat tatttaagct
    21661 atttaactta tctataaact tcgattctat atcatttgat tttgattcat gttttacttt
    21721 tgaattttta atttcattta gtagcatgtc attttctgaa ttatctttac ctaattgcaa
    21781 atcctcaatt tcagttgctt ttatttctac tttgtcttgt tcgttattct cttccacatt
    21841 attaggtacc acatctttat tgctagctaa tattttgttt acacagaata taatttctct
    21901 ttttaattct cttttcgcat ctgcttgatt tttaagaaat aaatctccac attctttctt
    21961 ttctaaactt atttttctaa gagatatatt aagaaggtct ttatataggt ttaaaacctt
    22021 ataatccttt tctaaacgtc ttcttctctc tgatagttcc attttatcat aagctaaaaa
    22081 actatttaaa tcattggctt ttagagagtc taatccctct ttcatagcct tatttacata
    22141 ctttctacat tttgctgtag ttaattctaa atctttttct aattcatcta tttcaggtat
    22201 gtacttatct actatccatt tgccaataag tggttctgta tttcttgcta atgtcttata
    22261 aaacaatata ttaaatttta aaagctctgc atattttgct tcattaaatt ctactttttc
    22321 aaatttcttt tccaaaacac catctagctt ttcatttatt ttagactctt gttttaaaaa
    22381 acttgctgtg acatttaaaa cagtgtttct tattatatta ttttcactca aaaccttcac
    22441 tccttaaatc aattatttta ttgtaatatt tacattgtgc aaagttgcta atttgattat
    22501 gatatctaaa taattattta ctaaatttgc tacatcttat atcatatcat attatttaca
    22561 tcattttact ttttcttttt atatctatct tatattatac catttttaat atctgtacta
    22621 acttatatta caatattcct caaaatttta aaagtagatt agacaaattt acaaataaaa
    22681 aaacatcagt ttaaactgat gtttttgact atcgaaataa ttaagcaagt ctataagcgg
    22741 agttctgtat tagataatca tctttctagg cctattgtca ccaataggct caagcgacct
    22801 acctaccgga gagtacgagc agcactcttt attcctatct tggtcttgct ccaggtgggg
    22861 tttacatagc caactagtcg cctagctgct ggtgagctct tacctcgcct ttccatcctt
    22921 accacaatag tggcggttta tttctgttgc actatcctta ggatcgctcc cactaggcgt
    22981 tacctagcac cctgctctat ggagctccga ctttcctcat gtaagattac atgcgattat
    23041 ctggcttact taatatttat tttacttagt tatgttaaca caaattcttt tacatgtcaa
    23101 agtaatatta tactaaaaat ttaaatttat tcaaaaatag tgtaatatag atatataaac
    23161 tacatttaac tcgaggtgat atattgaaaa aattatatag aatagtaatt aacattatac
    23221 tagtattagt aatactttac agtggattta atatatactc aaaacttacc aaatacaatc
    23281 atgatactaa aatatcctca gaacttcaaa aaaaagaata taaaaaagag gatttatcaa
    23341 agattaacag tgattttaaa ttttggcttt ctgttgagaa tacaaatata aattatccag
    23401 ttgtacaatc taaagataat tcttactatc ttgacaaaga tttttataaa aaagattcta
    23461 tttctggtac actgtttatg gattatagaa ataaatctat tgatgacaaa aatatcataa
    23521 tatatggaca taatatgaaa aataaaacta tgttcaacaa cctaaataag tttaaagatg
    23581 ctgacttctt taaaaaaaat aataaaataa aaataacctt gaatggaaaa gaatttttat
    23641 atgatgtttt ttctgcttat attgtagaat ctgattatga ttatctaaaa acaaatttta
    23701 acagtgaatc tgattatcaa aattacataa atgatattac ttctaaatca ttgtataaat
    23761 ctcctattaa ggtaaatagc aatgataaaa tagttacact ttctacatgt acatatgaat
    23821 ttgatgatgc cagaatggtg attcatggta gattgattta aaactcacag acacagttta
    23881 aaacaataat tttaaactgt gtcatctttt atacctataa tttataaatt agaccactaa
    23941 aagtatttaa tacaaaataa caaatacatc aaacaataaa aaacaataaa aaaagactat
    24001 gctaaaaaca tagtcttta
//
LOCUS       DAEOTL010000056        23842 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEOTL010000056 DAEOTL010000000
VERSION     DAEOTL010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.056"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            482..1681
                     /gene="hadA"
                     /locus_tag="KRH82_002612"
     CDS             482..1681
                     /gene="hadA"
                     /locus_tag="KRH82_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBG8655882.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            1720..2520
                     /gene="hadI"
                     /locus_tag="KRH82_002613"
     CDS             1720..2520
                     /gene="hadI"
                     /locus_tag="KRH82_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBG8655883.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            2535..3761
                     /gene="hadB"
                     /locus_tag="KRH82_002614"
     CDS             2535..3761
                     /gene="hadB"
                     /locus_tag="KRH82_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBG8655884.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            3761..4888
                     /gene="hadC"
                     /locus_tag="KRH82_002615"
     CDS             3761..4888
                     /gene="hadC"
                     /locus_tag="KRH82_002615"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBG8655885.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            4936..6069
                     /locus_tag="KRH82_002616"
     CDS             4936..6069
                     /locus_tag="KRH82_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBG8655886.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            6102..6887
                     /locus_tag="KRH82_002617"
     CDS             6102..6887
                     /locus_tag="KRH82_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBG8655887.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            6906..7943
                     /locus_tag="KRH82_002618"
     CDS             6906..7943
                     /locus_tag="KRH82_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBG8655888.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            8426..10057
                     /locus_tag="KRH82_002619"
     CDS             8426..10057
                     /locus_tag="KRH82_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655889.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(10192..11118)
                     /gene="fba"
                     /locus_tag="KRH82_002620"
     CDS             complement(10192..11118)
                     /gene="fba"
                     /locus_tag="KRH82_002620"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBG8655890.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            11448..11777
                     /locus_tag="KRH82_002621"
     CDS             11448..11777
                     /locus_tag="KRH82_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBG8655891.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            11777..12499
                     /locus_tag="KRH82_002622"
     CDS             11777..12499
                     /locus_tag="KRH82_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBG8655892.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPAGYISATTDKYDPTVLDLIDLSYLVFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            12526..13887
                     /gene="rlmD"
                     /locus_tag="KRH82_002623"
     CDS             12526..13887
                     /gene="rlmD"
                     /locus_tag="KRH82_002623"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBG8655893.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKSELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            14398..15432
                     /locus_tag="KRH82_002624"
     CDS             14398..15432
                     /locus_tag="KRH82_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBG8655894.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGIAAVVAGV
                     VYKKKKRKKI"
     gene            15519..15722
                     /locus_tag="KRH82_002625"
     CDS             15519..15722
                     /locus_tag="KRH82_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBG8655895.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            15893..16780
                     /locus_tag="KRH82_002626"
     CDS             15893..16780
                     /locus_tag="KRH82_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBG8655896.1"
                     /translation="MKLSKTLLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIK"
     gene            17313..17453
                     /locus_tag="KRH82_002627"
     CDS             17313..17453
                     /locus_tag="KRH82_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655897.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(18117..18437)
                     /gene="rhaM"
                     /locus_tag="KRH82_002628"
     CDS             complement(18117..18437)
                     /gene="rhaM"
                     /locus_tag="KRH82_002628"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBG8655898.1"
                     /translation="MNTIRKCFKMKLFKGFENEYKKRHDELWSEMIDMIHEYGGSNYS
                     IFLDEETNYLYGYIELKDAKLWDKSSETAICKKWWNYMSDIMETNEDNSPVSIELKSM
                     FYLK"
     gene            18623..18904
                     /locus_tag="KRH82_002629"
     CDS             18623..18904
                     /locus_tag="KRH82_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655899.1"
                     /translation="MKDETLEDILKQKTQAERYILEYIVTKNVKKLDNKKIVSILHTI
                     LCWEEINGTIVLTDKNILSLDEDIIISKHRRFIDIPKHKHNFIEFHLMS"
     gene            19028..19999
                     /locus_tag="KRH82_002630"
     CDS             19028..19999
                     /locus_tag="KRH82_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8655900.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFAQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASDEEDIIINFIIKPEFFDYIISLLENDNKIMNFLMTTLYTNYNLGEYIYFK
                     VSEKEEIQDIIEKIIIELYEPSVVNKVKIKLLVGLLLVELVKNSEDVENHAVDNYEKM
                     MIIEILKYIDKDYKKGSLSEIASNLNQGDYKISKLVKKHLGYTFKDLVQEKRLSKACE
                     LLVSTNLSIAEIIENVGYENLTYFYKIFKNKYGITPKEYKKNIKNSQ"
     gene            20206..21600
                     /gene="rhaB"
                     /locus_tag="KRH82_002631"
     CDS             20206..21600
                     /gene="rhaB"
                     /locus_tag="KRH82_002631"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBG8655901.1"
                     /translation="MRYYLAIDIGASSGRHIISYINNGKLEIEEVYRFKNNLIKKDGH
                     FCWDISKLFSEIKNGIKKCIKINKIPVSVAIDTWAVDFVLLDEKDNILGNCVSYRDNR
                     TDGIMEEAFKIIDKKELYLKTGIQFQKFNTIYQLLAIKNQQPDLLEKAKSFLMIPDYF
                     NFLLTGKKVTEYTNATTTQLVNTTTNNWDEEIINKLGFDKMLFAKIKTPKTILGSLKK
                     ELVEELGCDLEVILPVTHDTGSAFMSTPVKNRSILLSSGTWSLLGVELERPKCKLEAL
                     DYNFTNEGGYEYRYRFLKNIMGLWMIQEARKCYDSKHSFTELVEHARLSEGFKSIVDV
                     NDDRFLNPENMVQEIIKYCIETNQTEPQTVGEVAYCIFNSLAKSYSKSINEIEKIIEE
                     KLETISVFGGGCQNELLNELIAKESGKKVLAGPVEATALGNIVCQLIAKNELNDLEQA
                     RDIIRNSFDIIQYN"
     gene            21621..22877
                     /gene="rhaA"
                     /locus_tag="KRH82_002632"
     CDS             21621..22877
                     /gene="rhaA"
                     /locus_tag="KRH82_002632"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBG8655902.1"
                     /translation="MELKQRYEVAKKEYEKWGINVEEVLRVLSKVKISIHCWQGDDVT
                     GFEGNQQRLSGGIASTGNYPGKARNPQELRRDLDKALSLIPGKHKVNLHAIYAETGGS
                     FVDRDELKPEYFENWVKWAKERGLGLDFNPTIFSHPKSSDGLTLSHPDKKIRDFWIKH
                     CIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLEEILKVEINRE
                     YNLDCVESKVFGLGVESYTVGSNEFYLNFASKNNIISLLDTGHYHPTELVSDKLSSML
                     LFSDKVALHVSRPVRWDSDHVVILDDELKEIAKEIVRNDALDKVIIGLDFFDASINRI
                     AAWVIGTRNMIKALLSAMLMPHEELRKLQDEGDFTKRLAIMEEFKTYPMGDIWNYYCK
                     INNVAVKEDWIEVVKEYELTELLNRK"
     gene            22888..23703
                     /gene="rhaD"
                     /locus_tag="KRH82_002633"
     CDS             22888..23703
                     /gene="rhaD"
                     /locus_tag="KRH82_002633"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBG8655903.1"
                     /translation="MSIMEMNFIKDFMKITYDAWLKGWHERNGGNITYRLTPEEISGI
                     KEFITEEIEYIPIGVTVENLANEYFLVTGSGKFMRNISINTVQNVGIVKIDEKGENYA
                     IVWGLDKAKPTSEFPSHLMSHSIKKDKTNGLHRVIMHSHTTNLIALTFILPLEGKVFT
                     RELWEMATECPAVFPEGIGIVPWMVPGGIEIAKATQNLMEKHNIVIWAHHGTFCSGET
                     LDLTFGLMDTVEKSAEILVKVISMGGKKQTITGDNFRDLSKNFKVSISEDYLY"
BASE COUNT         9653 a         2620 c         4367 g         7202 t
ORIGIN      
        1 aattgttatt ttttagatta aatattatta aaaaattatc taagtttgaa attagttaac
       61 taacttgctg attaattaca atgataacat gtgtttttga gtttagcaat gaaaactttt
      121 tttgaaatgt caagcttttt cataaaaaaa tatataaaaa aaacttttat aagcagagaa
      181 agaatagcaa aatgcaatgg atagtggcaa gatgccacga tatgaaaaag attattcaat
      241 tgcatattgt taaaaaacat tcaaatcaag cgatattttg attaaatata aagttggcac
      301 gataaatgct taacaatata ggtgtaagac aataaaacaa taaaaaataa ttttaataat
      361 ttttaagtta ttttagataa gattaggaac tttgacatca gacagttaat atcagaaaaa
      421 agtattttat gagtgattta atcgaaattt tataattgat actattaagg aggaaaacgt
      481 tatgctttta gaaggagtta aagtagtaga actttcaagt ttcatcgcag caccatgttg
      541 tgcaaaaatg ttaggtgact ggggtgcaga ggttattaag attgaaccta tagaaggtga
      601 tggaataaga gttatgggtg gaacatttaa atctccagca tcagatgatg aaaaccctat
      661 gtttgaatta gaaaatggaa ataaaaaggg tgtaagtatt aatgtaaaat caaaagaagg
      721 agtagaaata ttacataaat tattatcaga agcagacata tttgtgacta atgttagagt
      781 tcaagcatta gaaaaaatgg gtatagctta tgaccaaata aaagataagt atccaggatt
      841 aatattctct caaatattag gatatggtga aaaaggacct ttaaaagata aaccaggatt
      901 tgactatact gcatacttcg caagaggagg agttagccaa tctgttatgg aaaaaggaac
      961 atctccagca aatacagcag caggatttgg tgaccactat gcaggtctag cactagcagc
     1021 aggaagttta gcagcattac ataaaaaagc tcaaactggt aaaggtgaga gagtaacagt
     1081 aagtcttttc catacagcta tatatggaat gggaacaatg ataacaacag cacaatacgg
     1141 aaatgaaatg cctttatcaa gagaaaatcc aaacagccca ttaatgacta catataaatg
     1201 taaagatgga agatggattc aattagcttt aatacaatac aacaagtggt taggcaaatt
     1261 ctgtaaggtt ataaatagag aatatatatt agaagacgat agatataata acatagattc
     1321 aatggttaat catgttgaag atttagttaa gatagttgga gaagctatgt tagaaaaaac
     1381 attagacgag tggtcagctt tattagaaga agcagactta ccatttgaaa aaattcaaag
     1441 ctgtgaagat ttattagatg acgaacaagc ttgggcaaat gacttcttat ttaagaaaac
     1501 atacgatagc ggaaatacag gtgtcttagt taatactcca gttatgttta gaaatgaagg
     1561 aattaaagaa tatacaccag caccaaaagt aggtcaacat actgtagaag tattaaaatc
     1621 tttaggctac gatgaagaga aaataaataa ctttaaagat agtaaagttg taagatatta
     1681 attagtaatt ctagattttt taaaaggaga atgctaaaga tgtacacaat gggattagat
     1741 ataggttcaa ctgcatcaaa gggagtaatc ttaaagaatg gggaagatat tgtagcttct
     1801 gaaacaatat cctctggtac tgggactact ggaccatcaa gagttttaga aaaattatat
     1861 ggcaagacag gtcttgcaag agaagatatt aaaaaagttg tagttacagg atatggaaga
     1921 atgaactatt cagatgctga taagcaaata agtgaattaa gctgtcatgc tagaggggta
     1981 aatttcataa ttccagagac aagaaccatt attgacatag gtggtcaaga tgcaaaggta
     2041 ttaaaattag ataataatgg aagactatta aactttctta tgaatgacaa atgtgctgca
     2101 ggtacaggaa gatttttaga tgtaatggca aaaataatag aggttgatgt atctgaactc
     2161 ggaagtatat ctatgaattc tcaaaatgaa gtatcaataa gcagtacatg tacagtattt
     2221 gcagagtctg aggttatatc acatttatct gaaaatgcaa aaattgaaga tatagtggca
     2281 ggtattcata cttcagtagc aaagagagtt tctagcctag taaaaagaat aggagtacaa
     2341 agaaatgtag ttatggttgg tggagttgct agaaatagtg gtattgtaag agctatggca
     2401 agagaaatca acacagaaat tattgtacct gatatacctc aattaactgg tgctttagga
     2461 gcagcgttat atgcttttga tgaagcaaaa gaatcacaaa aagaagtgaa aaatatataa
     2521 aaagagggat gaaaatgtct gaaaaaaaag aagctagagt agtaattaat gatttattag
     2581 ctgaacaata tgcaaatgca tttaaagcta aagaagaagg aagacctgta ggttggtcaa
     2641 catcagtatt tcctcaagag ttagcagaag tatttgactt aaacgtatta tatccagaaa
     2701 accaagcagc tggagtagca gctaaaaaag gttctttaga attatgtgaa atagctgaat
     2761 ctaaaggata ttctattgac ctatgtgcat atgcaagaac aaattttggt cttttagaaa
     2821 atggtggatg tgaagctttg gatatgccag ctccagattt cctactttgc tgtaacaata
     2881 tatgtaacca agttataaaa tggtatgaaa atatttcaag agaattagat atacctttaa
     2941 taatgattga tacaactttc aataatgaag acgaagttac tcaatcaaga atagattata
     3001 ttaaagctca atttgaagaa gctataaaac aactagaaat tatatcagga aagaaatttg
     3061 accctaagaa gtttgaagaa gtaatgaaaa tatcagctga aaacggaaga ctatggaagt
     3121 attctatgag tttaccagca gattcttctc cttctccaat gaatggattt gacttattta
     3181 cttacatggc tgtaatagtt tgtgctagag gtaaaaaaga aactacagaa gcatttaagt
     3241 tacttataga agaattagag gacaacatga aaactggtaa atcttctttc agaggggaag
     3301 aaaaatacag aataatgatg gaaggtatac cttgttggcc atatatagga tacaagatga
     3361 aaacattagc taaatttgga gttaacatga caggtagtgt ttacccacat gcttgggcat
     3421 tacaatatga agttaatgat ttagatggaa tggcagtagc atatagtact atgtttaaca
     3481 atgtaaacct agaccgtatg acaaaatata gagttgattc tttagtagag ggtaaatgtg
     3541 atggagcatt ctatcatatg aacagaagct gtaaacttat gagtttaata caatatgaaa
     3601 tgcaaagaag agcagctgaa gaaactggat taccatatgc tggatttgat ggtgaccaag
     3661 cagaccctag agctttcact aatgctcaat ttgaaacaag aattcaaggt ttagttgaag
     3721 taatggaaga aagaaaaaaa cttaatagag gtgagatata atggaagcta ttttatctaa
     3781 aatgaaagaa gtagttgaaa atccaaatgc ggctgtaaaa aaatataaaa gtgaaactgg
     3841 taaaaaagct ataggttgtt tcccagttta ttgcccagaa gaaattatac atgcagctgg
     3901 aatgcttcca gttggtatat ggggaggaca aacagaatta gatttagcta aacaatattt
     3961 ccctgcattt gcatgttcaa taatgcaatc atgtttagaa tatggattaa aaggtgctta
     4021 tgatgaatta tctggagtta ttataccagg tatgtgtgat acactaattt gtttaggaca
     4081 aaactggaaa tcagcagtac ctcatataaa atatatatca ttagtacacc cacaaaatag
     4141 aaaacttgaa gctggtgtaa aatacttaat cagtgagtac aaaggcgtaa aaagagaact
     4201 tgaagaaatt tgtggatatg aaatagaaga agcaaaaatt catgaaagta tagaagttta
     4261 caatgaacat agaaaaacta tgagagactt tgttgaagta gcttataaac attctaatac
     4321 tataaaacca tcaataagaa gcttagtaat taagagtggg ttctttatga gaaaagaaga
     4381 acatactgag ctagtgaaag atttaatagc aaaattaaat gctatgccag aagaagtctg
     4441 ttctggaaag aaagttttat taacaggtat attagctgat tctaaagata tattagacat
     4501 tttagaagac aacaatatat cagttgtagc tgacgactta gcacaagaaa caagacaatt
     4561 cagaacagat gtaccagcag gtgatgatgc gttagagaga ttagcaagac aatggtcaaa
     4621 catagaagga tgttcattag cttatgaccc taagaaaaaa cgtgggtcac ttatagtaga
     4681 tgaagttaaa aagaaagata tagatggtgt tatcttctgt atgatgaaat tctgtgaccc
     4741 agaagaatac gattatcctt tagttagaaa agatatagaa gatagtggaa tacctacttt
     4801 atatgttgaa atcgaccaac aaactcagaa taatgaacaa gccagaactc gtattcaaac
     4861 ttttgctgag atgatgagtt tagcgtaagt tcattaaaat aaatttacta taaaatatga
     4921 aaattggagg aagctatgtt atataacaaa gaacaagaac ttttaagaaa agcagtaaga
     4981 gattttgtta gtaaagaatt agatacttta ccagcagaaa tggataaaac aggtgtaatg
     5041 cctaaggaat taatcaaaaa attagctgat gcaaaattta taagcagtaa tatcccagaa
     5101 gaatatggtg gtgggggagc aggatatgtt tcttacgcta tagtaatgga agaaatagct
     5161 agaagatgtg cttcaacagc tacttttgtt acagctggtt cttctcttgc ttcattacca
     5221 atactttaca atggtactga agagcaaaaa caaaaatact taaaaggtat agcaacaggt
     5281 gaattaatag gagcatttgg tttaactgag ccaggagctg gttctgatgc aggtggacaa
     5341 caaacaacag cagaattagt tggagaccac tatatattaa atggtagaaa aactttcata
     5401 actaatggac cattctgtga tgtagctata gtaatagcag ttacagatag aagtaaagga
     5461 cttagaggaa catcagcgtt tatagtagaa agtaaatggg atggtttctc aacaggagct
     5521 catgaagata agatgggtat aagaggaact gaaacttctg acttaatatt tgaaaacgtt
     5581 aaagttccaa aagaaaactt acttggaaaa gaaggtcaag gatttaagat agcaatgggt
     5641 actctagaag ttggtagaat aggtgttgct gccttagctc taggaatagc tcaaggtgct
     5701 ttagatgaag ctgttaaata tacaaaacaa agagttcaat ttggtaagcc tatagctaaa
     5761 ttccaaaata ctcaatttac tatagctgac atggaaacaa aagtttgtgc agctagagga
     5821 ttagtttatg atgcagcaca aaagagagat gcaggaatga gagttgctca agaatctgct
     5881 atggctaaat actatgcatc agaaattgca aatgaagttg cttataaagc attacaactt
     5941 cacggtggat atggatttat aaaagattat gaaatcgaaa gaatgtacag agatgctaga
     6001 atcgtatcaa tatacgaagg aacatcagaa gttcaaaaaa tggtaatttc atcaaacgta
     6061 ttaaaataat aaataatcta atgaaattgg aggtatagac tttgaaaata ttagtttgcg
     6121 taaaacaagt tccagatact aacgaagtaa gaataaataa agaaacaggt actcttataa
     6181 gagatggagt tccaagtata ttaaacccag atgatgcaaa tgcattagag gaagctttaa
     6241 aaattaaaga tgagcatgat gatgtaacta taacagttat aacaatggga cctcctcaag
     6301 cagactttat gctaagagag tgtttagcta tgggtgctga tgatgcaata ttattaagtg
     6361 atagagcatt tggaggagct gatacttggg ctacatcaaa tactattgca gcgggaatat
     6421 ctaaagtagg tgactatgac ataatatttg caggaagaca agcaatagat ggagatactg
     6481 cacaagttgg accacaaatt gcagagaaat tagacattcc tcaagttaca tatgtacaag
     6541 atttcaaaat agaaggaaaa gatataatag ttcaaagaca attagaagat ggatacgaat
     6601 taataaaagt aagtacacct gtacttttaa cagcagtaaa agagttaaat acacctagat
     6661 acatgtctgt tgataaaata gtaaaagcat ataaacatga tgtaaaagtt tggacaattg
     6721 atgatttaga tgtaaataaa gaagaagttg gtttaaaagc atcaccaact aaagtattta
     6781 gatcatttac tcctgaacca agaggaaaag gagaaatctt agaaggtaaa gctgatgaaa
     6841 tagctagtaa aataataatc ggtctaaaac aaaagcacat tatataagtt ggaggagtac
     6901 aaactatgaa tgatataaaa gatttaagtt cttataaaaa cgtatggata tttgcagaac
     6961 aaagagaagg aaaaatagct ccagtagtta tagaattatt aggagaagga agaaaattag
     7021 ctaaagaagt agatgcagaa ctttgtgcaa tattattagg aaaagatgtt gatggattag
     7081 ctaaagaatt aatcactttt ggagctgaca aagtttatgt tgcagatgat gctcttttag
     7141 aaaaatatac aactgatgca tatacaaaag taataaaaga tgcaatagat gaaataaaac
     7201 cagaaataat gcttttcgga gcaactcata taggtagaga cttagcacct agaatagctt
     7261 caagagttgg aactggatta acagctgact gtactaagtt agaaatagac ccagaagata
     7321 agaaaataaa acaaactcgt ccagcatttg gtggaaacat aatggctaca atcatttgtc
     7381 caaaccatag acctcaaatg tctacagtta gacctggtgt tatggataaa gctgaaaaag
     7441 acgaaacaag aactggtgaa gttatagcat tagactacaa aataactcaa gatgatataa
     7501 gaactactgt tttagaaaca gttaaaacta agaaagattt agtatctctt acagatgcaa
     7561 atgttatagt atcaggtggt ttaggattag gtggaccaga aggatttgaa atgcttaaga
     7621 aattagctga caaattaggt ggagtagttg gttcttctcg tgcggctgtt gatgctggat
     7681 ggatagacca ttctcaccaa gtaggtcaaa caggaactac tgttaaacca aacctatata
     7741 tagcttgtgg tatatcagga gcaatacaac atttagcagg tatgcaatca tcagatttca
     7801 taattgctat aaacaaaaac ccagcagctc caattttaga aatcgctgac tatggagtag
     7861 ttggagactt acatgaaata gttccaatgc ttatagaaaa attagatagt gttgatgatt
     7921 tattagaagc tataaaagct taatagatac aaactatata aatattactg attgaataag
     7981 tcttattagt tagtaacata attattaacc ctttgataag ttattgctag tgtgtatttg
     8041 tcagttatta aaaagtctgt ttgaataaaa ttttataata caagataatc tggataatcc
     8101 ttatatgtat attgcttaca aattgtgagt tatattctgt aaggattatc tttgtttttt
     8161 taaataaatc ttaaatttaa ttaaattgta ttaaatagac aaataattac taaatatgtg
     8221 ataaaataca attaaaagca aaatgaaatt tttaacaaac tataatcatt aaaattatat
     8281 cttagttacg ttttaatgaa ataaactact tgaaaagacg aatattataa ggagttgatt
     8341 atatgtgctg atggtattta ttgtaagcaa acaataaatt ttgtatgtag ttcaataaat
     8401 tacttaatga aaggtgcgaa tattaatgga taataattta atagggctta tagaacatgt
     8461 agaaaatcca gccattttat gtaaagaatc aggcgaaata atatactgta atcatctaat
     8521 agatagtatt tttagttttc tagatataaa aaagcctaga aatataaatg aattagattc
     8581 aaattttgac aaaacagaaa tactgacaga tagtaaaaag aaaatagctt tcagagagtt
     8641 aaggatgact gcacatatat acaatatgaa agataataat aatgaaaata atatagttta
     8701 tttatttgag aagtctctaa tatctgataa agtaattgaa gatataatag agcatataga
     8761 tgaagttgtt gttgtgttta acaaagatgg ggtaattgaa aagatgaaca ctgtcagtga
     8821 tgagatatta ccttttaaaa gaactgaggt acttggtaga aatataacag accttgtgag
     8881 acaaggatta gttgaagaac caataatatt aaacatgctt aaagtgaaga aaaagattta
     8941 tagaaatatc gtttacccag atgggaagct tattgcatat acggcagttc caagatggga
     9001 ttctaaggga aagcttacag gaggagtact aacagggaga gatatttcaa gggttattaa
     9061 gcttgaatct cagataaaat atagtgatat atcagaagac acagagtata taagtcaaag
     9121 taagattatg gacaatataa aaaaagttgt taagagagct gcagcctcag attcttctat
     9181 atttataaat ggagaatcag gtgtaggaaa agaaataata gcaagaacaa tatataagta
     9241 tagttcaagg agagacaaac cttttatagc tataaactgt ggagctatac caaatgaatt
     9301 attagagtca gagttttttg gatatgaaga aggttctttt actggagcta agaaaaaagg
     9361 taaaaaggga ctttttgaag aggcgaatgg tggaactatt ttcttggatg agataggtga
     9421 gttaccaatg cagatgcaaa aaaaattact tagggttata caagaaaata ctattactag
     9481 aataggtggt agtaagccta taaaaataga tgttagatat ataagtgcta ctaatatttc
     9541 tcatgaagac cttagaaata accttaaatt tagacaagat ttgtactata gattaagtgt
     9601 tattccagta aaaatacctc ctcttagaga aagaaaagag gatatagtac cattagtaaa
     9661 ttatttctta aaactttaca atgaaaagta caatagagaa gtagaagttt cgcctaaagt
     9721 tattgagtta ttagaagaat attcttggcc aggaaacata agagaattaa aaaacatcat
     9781 tgaaagattt gtagtattat cagctaaaaa tgtaattgga gaagatgaat ttaacatgct
     9841 gataaattta gatatgattg ataatgaaac agatgattta tcaccaatag tggtaaatgg
     9901 aattatgaat cttaatgatg catataaaat agtggaccaa ataatgataa gtaaggctat
     9961 aaataagtat ggttcaataa caaaggctgc tgaagttata ggtatatatc cttctaccat
    10021 ccatagaaag ataaagagtg gacatattca cgtttagctg tcagtttaaa aagacaatat
    10081 aattaaaata ttataagata cataatttat acaacttaaa agagatggct taaaaataaa
    10141 tttaattact ttaagtcatc tcttttcttt tataaatatt taaaagttat attagtttat
    10201 agagttagca gaacctaaaa catcatctat cttgctttca actacagctt gtatagcatc
    10261 tctaccagca ccaatgtatt ttcttgggtc aaattctttt ggattttcag ctaagaattt
    10321 tctgatagca gcagtcatag ctagtcttaa gtcagtatcc atgtttattt tacaaacagc
    10381 catagaagat gcttttctta acatatctac aggtacacct ttagcaccag ctatatttcc
    10441 accaaattca ttacatgtag caacagcatt ttggtcaaca gcagatgcac catgaagaac
    10501 tattgggaaa cctggtaatt tgctttggat ttcttctagt atatcgaatc ttaatttagc
    10561 ttctcctttg aatttgaaag caccatgaga agttccaata gctattgcta atgaatcaac
    10621 acctgttctt tcaacgaact caactgcctc agctggttga gtatacttgt gaacatcaga
    10681 agtaacatca tcttctgttc cagctagaac accaagttct gcttcaacaa caacaccttt
    10741 agagtgtgca tattcaacag cttctttagt tattctaaca ttttcttcaa agtcaaaatg
    10801 agaaccatct atcataactg aagagaaacc agcatcaata caagttttaa tagcatccat
    10861 atttggacca tggtctaagt gaagagccac atctacacct atttcatcag aagcagcctt
    10921 aaccatttca actaatgtat gaggtccagc atatttaaca gctgacatag aagcttgtat
    10981 cataacataa gaatttttag ctttagcagc ttttaaaaca ccttgtaatt gttctaagtc
    11041 acttatgtta aatgcaccta tagcaaatcc accttcgtaa gcttttttaa acatttcttt
    11101 tgtagtaatt aatgccattt taaactcctc ctattaactt ttaaaattta cccatcactt
    11161 atattataac gttaaatcaa aaaaagtaca tagtaaattg taataactat aaattacaag
    11221 tataatgtta aatagaagac aataggatta aataaaataa taaagaatat aaacaattta
    11281 ggaaaattag ctatataatg ctaactataa gggtaggaac taccttatta gtttggagat
    11341 actgataaca atagttgtct tgaccaagaa gttgccactt caaacgttat cgaagggaat
    11401 taagtggatg ataattcact aaaaatttaa aataaaggag ataaactatg ccacagataa
    11461 aaataagagg aattaatgaa aatgatatat gtaaaataag tgaaaaaatg ataaatgatt
    11521 tagttgaagc tgtaaaatgt ccaagagact actttgaaat agaatgtata aagtcagttg
    11581 caataagaga tggtaaaata gcagatgtat atccttttgt tgaagtagct tggtttgata
    11641 gaggacaaga agtacaagat atagtagcaa gaataataac tgatagtata agaaataatt
    11701 tagatgtaga aagtatggat ttagcattta cagtatttga aaaagaaaaa tattatgaga
    11761 atggagagca tttttaatgg ctaaaaagca acgtatagat aaaattcttt caaatttagg
    11821 ttatggaagc agaagtgaaa taaagaagta ttgtaaacaa gggtctgtag tagtaaatgg
    11881 aagtgaagtt tcaaatccag gaactcaagt agacactgaa aatgatgaga tattatttaa
    11941 tggagaagaa gttatatata gagaatatat atatttgatg atgaataaac ctgctggata
    12001 tatatcagca actacagata aatatgaccc aacagtatta gatttaattg atttatcata
    12061 cttagttttt gaaccatttc ctgttggaag gttagataaa gacacagagg gattattagt
    12121 tttgactaat gatggaaagc tttctcatag agttttatct cctaagaagc atgtgcctaa
    12181 gacttattat gcaaaaattg atggagtagt tactgaagaa gatgtagaag cttttttaga
    12241 aggtgtagtg cttgatgacg gatataaaac tatgccatca cagttaaata tattaaaaag
    12301 tgatgatgaa tcagaaatag agcttacaat acatgaaggt aagtttcacc aagtaaaaag
    12361 aatgtttgaa agcgtaggca aaaaagtagt atacttaaaa agattgtcta tgggcaattt
    12421 aaaattggat gaaagtttag agttaggtga gtatagagag ttaacagatg aagaagtaaa
    12481 attgattgaa gaaagataat aaagatacta tagtaaattg gaggaatgtc tgtgaagaaa
    12541 aaagatgtta tagaatttga agtagataaa atggaatttg gtggtacatc tttaagccaa
    12601 gttggagata gagttatcca tatgaagggt ggaataagtg gtcaaaaggt gagagctgga
    12661 gttaaaaaag ttagaagtaa gaaagctgaa gttaagatga tagaattatt agagaactca
    12721 ccacttgaaa ctgaagaaac ttgcaagcac tttagagagt gtggaggatg tacactattg
    12781 tctgtgccat atgaaaaaca attagaaata aaagaaaaac aagttatgga tttattttta
    12841 aagcaagatt tatttggatt tcagttttta gggatagaag gaagtccaga aaacaaatat
    12901 tatagaaata agatggaata tacttttgga gatgaagtaa aaaatggacc tttgacatta
    12961 ggtcttcata aaaaaggaaa gcatatagat atacaaactg ttgaggagtg tatgttggtt
    13021 gatgaagact tctcaaagat attagtttct agtgtagagt ttttcaatga aaaaaagctt
    13081 ccttattata gaacaatgaa tcacaaagga tatttgagac atcttgtagt tagaaaaggg
    13141 attcacacta atgagattat ggttaatata gtaacttctt ctcaagaaga ttttgatatg
    13201 tatgagttta aagatatgct tttagggatt gatttaaaat ctgagttggt gggagtactt
    13261 catactatta atgatggttt agcagatgca gtccaatgtg atgagttaag agtattgtat
    13321 ggaagagatt atatacaaga agaaatttta ggtcttaagt ttaagatttc accattttcg
    13381 tttttccaaa ccaatactaa gggagctgag gttctttata gtattgctag ggattttatt
    13441 ggagattaca atgataaagt tgtatttgac ttgtatagtg gtactgggtc tattggacag
    13501 gttatggctg gtgctgctaa gaaagtgtat ggtattgaga tagttgagga agctgttgtt
    13561 gctgctaatg agaacgctaa gttgaatgga cttactaatt gtgagtttat tgctggggat
    13621 gtggctaagg ttgttaagga tttaaaggac aagcctgatt tgattattgt tgaccctcct
    13681 agaccaggca ttcataagga tgctattagg gatatttgtg gatttggtgc taaggagatt
    13741 gtttatattt cttgtaatcc taagtctttg gttgttgatt tggttgattt taaggggtat
    13801 ggttatgaga ttaagatggt taagtgtatg gatatgttcc caaatacgcc acattgtgag
    13861 actgtagtta aacttattag agaataacag ggtttcagac ttttatagtg tgtcttaaaa
    13921 gtagatttgc taccataatt atttttgggt ggcaaattta ttctacaatg atttcaaaaa
    13981 tatttaccgt ctggtttctc atgttattag ttacatgtaa atatgtatcc atagttgttg
    14041 aagttttagc atgtccgagt atatgctgga tatcttttat attagtacca ttttctaata
    14101 acatagtatc agggttttta aaataaagtg tgtattcttc taaagtagtg ataattaaaa
    14161 tatcaaatat cactatacaa aggaaagtgc acgcttttta tgtttaacaa aaacgaaata
    14221 ttaaaaaact tattgaagaa tatgatgtca aaacaactac agatattcaa gatatgctaa
    14281 aagatttatt tacaaataca attcatcaaa tatttacatt gtcgaatttt aacggtttaa
    14341 acataatata ttgactgata taataaaatc atagaatatt ttagggggaa atagattatg
    14401 tttaagaaaa agttaatagc tgttgcaatg agtataacta tgattagtgt agggagcttt
    14461 tcgtatgctc attcaggaag aactgattca tcaggaggtc atcgtgataa taaaaataaa
    14521 tctggattag gaagttatca ctatcattgt ggtggttatc cagctcattt acataataat
    14581 ggtggttgtc cttatactgg aggaggaagc agttctggaa caacaacttc ggttaataat
    14641 gaagaaaagc aaaagaggtc tgttggagaa aaaggatata atcaagggta tgaagatgga
    14701 tataaaggaa attatagttc atcaaattat agtggagatt atagtgatac atatgaatca
    14761 aagtactcag aaggatatga aaaaggtaag gctaaattag aagaggaaga aaaggtggct
    14821 aaagagactg gatataattt agggcttaca ggtgctaaat ctaataatac atatgaaaaa
    14881 gaagttttaa aaaatgctta tgataccgga tattcaaccg gatacaatga atataagact
    14941 aaaaagatag aagaatataa agctaaaggg atagaggata gcaataaaga taaagaaaaa
    15001 atgacatttg aagaaaacat agattctgaa tttatagatg cttataataa tgcttatgac
    15061 gaaatacaag aacaattaaa aaatgattac actactcaag gatttgagag tgctatcaaa
    15121 ggagaaagat ttgacacatc aactataggt aatgttaaat atgctaattg gtttaaagaa
    15181 ggatatgata atggtaaggt taagttacct aaagcaaaag aaagtgtata taatcaaggt
    15241 tacaatgaag aagattttag tataccagat gaaatgaagt ctattgaaac taagttaaaa
    15301 ggtgtatatg atgaaggttt agaaaaaaga gaggaagaga aaagtagaaa tgctacttat
    15361 ggggttggag ctggaatagc agctgtagtt gctggagtag tatataagaa gaaaaaacgt
    15421 aaaaagatat agatgctaga tataccaatg atgacaagtg tataacaaat ataattttaa
    15481 gtataaatat ttaaaatata gaagggaagg ttatatctat gggatttaac tttaggaaaa
    15541 gcataaatct aggaggagga ctcaaattaa atttaggtaa gaagagtgta ggtataagtg
    15601 ctggtgttaa aggtgctaga gtgtcagtta attcaaaagg aagaaaatca gctacattga
    15661 gtatacctgg aactggaata tcatatacaa aaactagtac aaagaaacgt aaacctaaat
    15721 aaatatttga tatactaaga aatagactgt tacaaatagt ctatttttta gtatatagat
    15781 ttaaaaagtg acaaaatttt gaaatataaa ctaatttcat aaaggaaaat attcttttat
    15841 gtaaaattat aatatttaag taatattata aaatttatag gaggatttca ttatgaaatt
    15901 aagcaaaaca ctattggcaa tagggatgtc tgtttcatta ttgattgcta gttgtccaac
    15961 atcaaacgct cttagttcta ttaattcaat aaaaggtaca aataagtatg aaacagcagg
    16021 tttaatagca gataaacaaa attatgatat tgcaatactt attaattctg aaaatggatt
    16081 atctgatgga ttgtcagcaa gtggattgtc aggagctaaa aatgccccaa tattgttaac
    16141 taagaaagat acaatccctt cagaaacatt aaaaagatta gaaaaggtaa aagaagtata
    16201 tctaattgga ggaaaaaatt cgataggagc atcagttcag aaaatattaa gtgataaaaa
    16261 aataagcata aatagaataa gtggaactga tagaatagat acaagtcata aagttgcaaa
    16321 agaaatagga agagtaagta cggttaaaaa agtaatatta actaatgctt ttaaaggcga
    16381 accagatgct atgagtgttg cttctatagc agttagagat aaatctccaa tagtattaac
    16441 tgatggaaat actacaagtt ttgctacaga tggattagaa acttatgcaa ttggtggaaa
    16501 agtcagtatg agtgataagt taataaatga aactaaagca acaagaatag gtggagtaga
    16561 tagatacgat acaaataaac aaataataaa taaattttat aatggctcaa aagaatttta
    16621 catagcaagt gggactgatt tagtttattc tttagttggt tctacaattg cacaaaaaac
    16681 acctatagtg ttagttggaa atggaagtaa taagagtata ttaaaaaatg caagtaaaat
    16741 aactgctatt ggaaatattg atgatgttgt tataaaataa tgtttaaata taactaataa
    16801 tgttggggat tcaaatacag gtattgtaaa agatactaat tcaaataata cgaacaaacc
    16861 aagtaatgag cctagctcta ataatcctgg attaactgat aaaagtacag tatatgtaac
    16921 tcctaatgga aaatcatatc atctaacaaa aaattgttct acactaaaaa gaagtaaaac
    16981 aataaataaa gtaacattaa aacaagctaa gtcacaaggt aaaatagacc cttgtaatgt
    17041 ttgtgtaaaa taatgtatta gccaaatata tattaaaaaa gacaattaat taagattgtc
    17101 ttttttattg aagaaatata aatttatatt atgtattatt aaaaagaaaa ttattaatta
    17161 taaaaaataa taataaagac gataagtatt aaaattttat gtttccaata tttatgatat
    17221 aattaatatg gcaaggaata aatatttgaa aaagctatga gtggtgtttc catggaagtt
    17281 tcttcacttt cttatgagag gaggtgaaaa ctatggaaaa tctaatgatg agtattataa
    17341 ctggtgttat agccagttac atttacgata aattaaagag ccactctgag cgaccaacta
    17401 agagtggctg ggaacttaat ataaagttcc agaaaagtaa atcttcaaaa taatttgttg
    17461 aaggaaacat cactcaaagt taagtaaaat atgtttcctt gcttttatta tatcacaaac
    17521 taaaaatatt aacacaaaat tttgtgaata tatacttatt attgttctaa aaaaatatgt
    17581 aaataattga tttgatttca tagaattatt gttgtaatgt ttagttaaat atacacaatc
    17641 tcaattaaag aagataagta ctataaattc atatcaaaaa aatatataaa cttttaagtt
    17701 ataattttat aaaaagtctt ttagtatcat tatttcaaga ggaattaaca tatgaaaaaa
    17761 taacttcatt agaaaagtgg ataaaaaact ggtaagaaga tgactaaaga ttacatatac
    17821 tattacttaa attaaaaatt taatataaac aacacaagat atatcaatta ttctaaagtt
    17881 aagtagtctt actgaatcat ctttgggaat aattgtttca atgtctagta gaaataccac
    17941 ttgtttataa catctttagc tactataatc gaaatatgtt tttagttttt cacagaacaa
    18001 ttatcacata gactagaggt ttttaggaat cacttatctt ttttatacaa aaaggagata
    18061 attcaaattt ttattttgat atatccccat tttgtgattt ataataattt ttgtccttat
    18121 tttaaataaa acatagattt aagttctata gatacagggc tattatcctc attagtttcc
    18181 attatatcag acatataatt ccaccatttt ttgcagattg ctgtctctga acttttatcc
    18241 catagtttgg catctttaag ttctatatat ccatataaat aattagtttc ttcatctaga
    18301 aaaatagaat agttactacc accatattca tgaatcatat ctatcatctc agaccataat
    18361 tcatcatgac gtttcttgta ttcattttca aatcctttaa aaagcttcat cttgaaacat
    18421 ttgcgtattg tattcataaa aaaatacctc ctaaatttta agtatttacc tataaatgta
    18481 ttttaaaaca aaaaaaggta tttttaaatg tcataattta acattattac tgtcaaaaac
    18541 taatatgata caattagata aagaatattt gtaatataat ttaaaactgt aataaagtat
    18601 agctaaatct ggggggatat aaatgaaaga tgaaacgcta gaggatatac ttaaacaaaa
    18661 aacacaagca gaaaggtaca tcttagaata catagttact aagaatgtaa aaaaactaga
    18721 taataaaaaa atagtgtcta tattgcatac tattttatgt tgggaagaaa taaatggaac
    18781 tatagtacta acagataaaa atatactttc tttagatgaa gacattataa tatctaaaca
    18841 tcgtagattt atagatatac ccaaacataa acataacttt atagagtttc atctaatgag
    18901 ttaatatata attttttatc aggaactata cacaaaggaa aaagatgtga taattattat
    18961 atatttaatg ctaaaaataa ttttaaattg aaacaactag tagttgaact aactaaggag
    19021 gtagctcatg agacaatata ttcatgataa gttgagggaa ataacagaag aagaaaaaaa
    19081 tatattagaa ggaaattata taatagataa aagtatttat actgataatt ctcaatttat
    19141 aatagatagc aacaaattat tgaatataga tgagttgata catataagaa aacatacaag
    19201 atttgcacaa tttccaaaac ataagcataa ttatatagaa tttaattatg tttatagagg
    19261 aaagttagta caaactatag atgaatataa aattaattta aaacaaggag aattaatatt
    19321 tttaaatcag catgttattc atgaaataga agctagtgac gaagaagata taataattaa
    19381 ttttataata aaaccagagt tttttgatta tattatatct ttgttggaaa atgataataa
    19441 aataatgaac tttttaatga ctacattata tactaattat aatcttggag aatatatata
    19501 ttttaaagta tctgagaaag aagagattca agatataata gaaaaaatta taatagaatt
    19561 gtatgaacca agtgtggtta ataaggtaaa gattaaatta ttagtaggat tattattagt
    19621 agaattagtt aaaaattctg aagatgtaga aaatcatgca gtagataatt atgaaaagat
    19681 gatgattata gaaatactaa aatatattga taaggactac aagaaaggta gtttatctga
    19741 aattgcaagt aatttgaatc aaggtgatta taaaataagt aaactagtaa aaaaacatct
    19801 tggatatact tttaaagatt tagtgcaaga aaaaaggtta agtaaagcat gtgaattatt
    19861 agtatctact aatttatcaa tagctgaaat tatagaaaat gtaggttatg aaaatttaac
    19921 ttatttttat aaaatattta aaaataagta tggtattaca ccaaaagaat acaaaaaaaa
    19981 tataaaaaat agtcaatagt aaaattagaa tctataaaat agattctttt ttattattaa
    20041 ataaaccatt ttaatagctc tgaagatatt atattttgaa aattattatt gagaataaag
    20101 ttatattgca aattaggtta ataaatatga caaatttaga tattaaatga atatactaac
    20161 atcttgtata attcaattaa taaataaatc taaggaggaa aagtcttgag atactattta
    20221 gcaattgata taggggcatc tagtggaaga catattatct cttatataaa taatggaaag
    20281 ttggaaatag aagaagtata tagatttaag aataatttga ttaaaaaaga tggtcatttt
    20341 tgttgggata tatcaaagct attttctgaa ataaaaaatg ggataaaaaa atgtataaaa
    20401 ataaataaaa ttccagtaag tgtggctata gacacatggg ctgtagattt tgtgttactt
    20461 gatgaaaaag acaatatatt aggtaactgt gtatcataca gagataatag aactgatgga
    20521 attatggaag aagcctttaa aataattgat aaaaaggaac tatatttaaa aacgggaata
    20581 caatttcaaa agtttaatac tatatatcaa ttattagcaa taaaaaatca acagccagat
    20641 ttattagaaa aggcaaaaag ctttctaatg attcctgatt attttaactt tttattaact
    20701 gggaaaaaag ttacagaata tacaaatgca acaactacac aattagtaaa tacaacaaca
    20761 aataattggg atgaagaaat aataaataaa cttggatttg acaagatgtt atttgctaaa
    20821 ataaaaactc ccaaaacaat actaggtagt ttaaagaaag aattagtaga agagttagga
    20881 tgtgatttag aagtcatttt accagttact catgatacag gttcagcttt catgtctact
    20941 cctgtaaaaa atagaagcat tttattgagt tcaggaacat ggtctttatt aggagtagag
    21001 ttagaaagac caaagtgcaa attagaggct ttagattata attttactaa tgaaggtgga
    21061 tatgaatata gatatagatt tttaaaaaat ataatgggtt tatggatgat acaagaagct
    21121 agaaagtgtt atgacagtaa gcactctttt acagaactag tagagcatgc aagactatca
    21181 gaaggattta aatcaatagt agatgtaaat gatgatagat ttttaaatcc tgaaaatatg
    21241 gtacaagaaa taataaaata ctgtatagaa actaatcaaa cagaaccaca aacagttgga
    21301 gaagtagcat attgtatttt taacagttta gcaaaaagtt atagtaaatc tataaatgaa
    21361 atagaaaaaa tcatagaaga aaaattagaa actataagtg tatttggtgg aggatgtcaa
    21421 aatgaactgt taaatgagct tatagcaaaa gaaagtggta aaaaggtatt agcaggacct
    21481 gttgaagcta cagcattagg taatatagta tgtcaattaa ttgctaagaa tgagctaaat
    21541 gatttagaac aggcgagaga tataataaga aattcatttg atataattca atataattaa
    21601 tctgaaaaag gagataagtg atggaattaa agcaaaggta tgaagtagct aaaaaagaat
    21661 atgaaaaatg gggaataaat gtagaggaag tattaagagt tttatctaaa gttaaaatat
    21721 ctattcattg ttggcaaggt gatgatgtaa cagggtttga aggaaatcaa caaagactat
    21781 caggaggaat tgcatctaca ggaaattatc ctggaaaggc tagaaatcct caggagttaa
    21841 gacgagattt ggataaggct ttaagtttaa taccagggaa acataaagtt aacttacatg
    21901 ctatatatgc agaaactggt ggaagctttg tggatagaga tgagctaaaa ccagagtatt
    21961 ttgaaaattg ggtaaaatgg gctaaagaaa gaggattggg attagatttt aacccaacaa
    22021 tattctctca tccaaaatca agtgatgggt taacattgtc acacccagat aaaaaaatac
    22081 gtgatttttg gataaagcat tgcatagctt ctagaaaaat aggcgaatac tttggaaagg
    22141 agcttggtca gacttgttta acaaacatat ggataccaga tggatacaaa gatataccaa
    22201 gtgatagatt aggtcctaga agacgcttaa aggaatcact agaagaaata ttaaaggtag
    22261 agataaacag agaatataat ttagattgtg tcgaatcaaa agtttttgga ttaggtgtag
    22321 aatcttatac agttgggtca aatgagtttt acttaaattt tgctagtaaa aacaacataa
    22381 tttcattatt agatacaggg cactatcatc ctacagaact tgtttcagat aaattatcat
    22441 caatgctatt attttcagat aaagttgcac ttcatgtaag tcgtccagtg cgttgggata
    22501 gtgaccatgt agttatatta gatgatgaac taaaagaaat agccaaggaa atagtaagaa
    22561 atgatgcttt ggataaagta ataataggac tagacttctt tgatgcaagt ataaatcgta
    22621 tagcagcatg ggtaattgga actagaaata tgataaaagc attgttatca gctatgttaa
    22681 tgcctcatga agaattaaga aaattacaag acgaaggcga ttttacaaaa agattggcta
    22741 taatggaaga gttcaaaaca tatccaatgg gagacatatg gaactattat tgtaaaatta
    22801 ataatgttgc tgttaaagaa gattggatag aagtagtaaa agagtacgaa ttaacagaat
    22861 tattaaatag aaagtaggta agggtatatg tctataatgg aaatgaactt tatcaaagat
    22921 tttatgaaaa taacttatga tgcttggtta aagggatggc atgagcgtaa tggggggaat
    22981 ataacgtata gattaacacc tgaagaaata tctggaataa aagaatttat aacagaagaa
    23041 atagaatata ttccaattgg tgtaacagtc gaaaatttag ctaatgaata tttcttagtt
    23101 acaggaagtg gcaaattcat gagaaatatt tctataaata ctgttcaaaa tgtaggaatt
    23161 gttaaaatag atgaaaaagg tgaaaattat gcaatagttt ggggattaga taaggctaaa
    23221 ccaacaagtg aatttccatc tcacttaatg agtcattcta taaaaaaaga caaaacaaat
    23281 ggattacata gagtaataat gcattcacat acaactaatc tcatagcatt aacttttata
    23341 ctgcctcttg agggtaaagt atttacaaga gaattatggg agatggctac agaatgtcca
    23401 gctgtatttc cagaaggaat tggaatcgta ccttggatgg tgccaggtgg gatagagata
    23461 gcaaaagcta cacaaaatct aatggaaaaa cataacatag taatctgggc tcatcatgga
    23521 acgttctgct caggagaaac tttggactta acatttggtc ttatggatac agtagaaaaa
    23581 tcggctgaga tattagtaaa agtaatatct atgggaggga aaaaacaaac aataacagga
    23641 gataacttta gagacttatc aaaaaatttt aaggtttcaa tatcagagga ttatttgtac
    23701 tagataagat aaaagataaa caaagctatg ataacttatt atgtacaatt aataaaacac
    23761 tatgagagag gaggtgatta aaagatatag aaagtaaatt cacttaagaa aatagtttaa
    23821 gaataaactg gagtttataa ta
//
LOCUS       DAEOTL010000057        23821 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEOTL010000057 DAEOTL010000000
VERSION     DAEOTL010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23821
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.057"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            8..682
                     /gene="fsa"
                     /locus_tag="KRH82_002634"
     CDS             8..682
                     /gene="fsa"
                     /locus_tag="KRH82_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBG8655904.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            complement(804..2198)
                     /locus_tag="KRH82_002635"
     CDS             complement(804..2198)
                     /locus_tag="KRH82_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBG8655905.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFTFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLET"
     gene            complement(2276..3622)
                     /locus_tag="KRH82_002636"
     CDS             complement(2276..3622)
                     /locus_tag="KRH82_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8655906.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     regulatory      3872..3974
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            4068..5444
                     /locus_tag="KRH82_002637"
     CDS             4068..5444
                     /locus_tag="KRH82_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBG8655907.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(5558..6703)
                     /locus_tag="KRH82_002638"
     CDS             complement(5558..6703)
                     /locus_tag="KRH82_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBG8655908.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIILDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            6956..7663
                     /locus_tag="KRH82_002639"
     CDS             6956..7663
                     /locus_tag="KRH82_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655909.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            7710..9305
                     /locus_tag="KRH82_002640"
     CDS             7710..9305
                     /locus_tag="KRH82_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655910.1"
                     /translation="MSNLSILIKNNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKVLMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVRIFKNL"
     gene            9408..10490
                     /locus_tag="KRH82_002641"
     CDS             9408..10490
                     /locus_tag="KRH82_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBG8655911.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            10639..10800
                     /locus_tag="KRH82_002642"
     CDS             10639..10800
                     /locus_tag="KRH82_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBG8655912.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            11141..12409
                     /locus_tag="KRH82_002643"
     CDS             11141..12409
                     /locus_tag="KRH82_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBG8655913.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            12604..13392
                     /locus_tag="KRH82_002644"
     CDS             12604..13392
                     /locus_tag="KRH82_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBG8655914.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            13392..13841
                     /locus_tag="KRH82_002645"
     CDS             13392..13841
                     /locus_tag="KRH82_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBG8655915.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            13845..16109
                     /locus_tag="KRH82_002646"
     CDS             13845..16109
                     /locus_tag="KRH82_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8655916.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIETSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            16249..16560
                     /locus_tag="KRH82_002647"
     CDS             16249..16560
                     /locus_tag="KRH82_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655917.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            16846..17346
                     /locus_tag="KRH82_002648"
     CDS             16846..17346
                     /locus_tag="KRH82_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBG8655918.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            17403..18389
                     /locus_tag="KRH82_002649"
     CDS             17403..18389
                     /locus_tag="KRH82_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBG8655919.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            18439..19161
                     /locus_tag="KRH82_002650"
     CDS             18439..19161
                     /locus_tag="KRH82_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBG8655920.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            19190..21124
                     /locus_tag="KRH82_002651"
     CDS             19190..21124
                     /locus_tag="KRH82_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8655921.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYISEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMALNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            21117..22385
                     /locus_tag="KRH82_002652"
     CDS             21117..22385
                     /locus_tag="KRH82_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBG8655922.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKHLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            22712..23752
                     /locus_tag="KRH82_002653"
     CDS             22712..23752
                     /locus_tag="KRH82_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655923.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT         9193 a         2497 c         3952 g         8179 t
ORIGIN      
        1 tattttaatg caactaatct tagatacagg taatgtggag gagattaagg agttatgtac
       61 ttgtttacca atagatggtg taactacaaa tccaagtatt gtttcaaaag aaaaaaagaa
      121 ttttaagcaa cttataaatg aaattggtga gattataggt gaggatatgc ctatacatgc
      181 tcaagtgtta agtacaaagt atgaagaaat attagaagaa gcattatata taagtagttt
      241 gagaaaaaat atatatgtaa aaatacctgt aacacaagat ggtttaagag ctataaaaga
      301 ccttcacaga aaaggtgtaa aaataactgc tactgcaata ttcactgctc atcaaggttt
      361 tttagctgca aaggctggag caaattatat tgcaccttat gtaaataggc ttgataatat
      421 atctggtgat ggagtagcta tggtttcaga acttataaaa ataatagata cttataaaat
      481 ggatacaaaa gtacttgcag ccagttttaa aaatgcacaa caagttatag aattaatgca
      541 acatggggtg catagtgtta cagtaccata tgatatttgt aaatctatga tgaatcatcc
      601 attaactgat tggagtgtag ataagtttat agaggattgg gagaatactt ttggaaaagg
      661 aagtaaaaca aataatattt agtattatgg taaaagagta gttttgtcca atttcacaag
      721 aacttatata aaaagatgaa aatatgaatt ttctttttaa taatttcgtt attatcttaa
      781 gttaattcat attttcatct tttttaggtt tctagtccta taaatttcca ccaagggaat
      841 gttatacata ttattataaa gtaggttaaa ggaatcaaag ttaaaccgta tttgaaaata
      901 accttgctat tatacagatt ttcaccatga ccaaccatta ttgtagcatg atgaaatggt
      961 aatatgtact gtatgcttac tataatgtag acaaatagac ataaagtaac actattttcc
     1021 tttagtatat gtaaacttcc aagtaatggt attactacag atgatgtagt gacagcactt
     1081 ccaagacata tattcaagat tattgtgaga gttatcaaaa acaatattga aataatttct
     1141 gaagagtttg gtataaactt tatcaaataa tttcccatta tatctacaac tccagagtac
     1201 tttaacactc ctccaattga aaatgctgct ataaaaaaaa taaggacctt ccaatttatt
     1261 tcttttaaag tactaaatcc aactattttt cttagtaata aaagaagtac acaaattgac
     1321 attataatta atgtgtttat gttatgtatg aactgagtta aaaacataaa aaacattatt
     1381 cctaggcata aaaatacgtg tttttgttct ttgtttagca aattaaattc tttttttaaa
     1441 ttagaatatg aaaaatgaag tttattaccc tcaagatttt cattagaaat aaattttatt
     1501 gaatgcaatt cttttttaaa gacaaaggta aataaaaaat aagttataaa acaagtaatt
     1561 atagttggaa cagacatata aaaagcccat tgaccccaat ttatattaca atttccaagt
     1621 tctagtacaa cataatttag aagagtgtct ccatttacaa aaaacattga tgtaaaggta
     1681 gatgctgtaa atatactaaa taaaagtata gattttgaat cttcagttat ctgttgttct
     1741 tttaaaaact ccttgtaaaa agcagataca agaataaccc ttggaaatgg ttgtgggata
     1801 aaaaatatta aaagtatacc taaaatatac gataaaagaa tcattttttt aggggtattt
     1861 acagtattta aaattaactt ctcagaaata atttttgcga cacctgtttt tgtaactgca
     1921 ttagtaatta tgtatgcaag aattattatg taaaaatttt ctgtaaataa aaactgtaaa
     1981 ataaccttta ttggtgcaat gttaaatata aacgctagaa ttacaaaaaa caatgcaaca
     2041 aaagtttttt caactgagtc tacagcccat atcaagatag ttaaaaaaga taagcatata
     2101 gaaaatttta tgttgaaact gtaattaaga gagaagtaga gaattatggt agctataaca
     2161 gtcatataaa attgttttgg cttaagaata atacccattt ttatattcac ctccataatt
     2221 tattatatca taatggaggt gaatacaatg aatgtgaata cattttataa aaagattatt
     2281 cattgattct atgatttaca atagctttag ttttccaatg tcctttctta tagtagataa
     2341 ctgtaacaat aagacctaaa gtccaaccaa aaggaatacc catccaaatt ccgtctgttc
     2401 caaaaaattt agaaagcata taagaagctg gaagtcttcc aagccataaa gatactattg
     2461 agcttataag tgcaaacatg gaatcaccag cacctttcat tgcacttgaa agtacaaaag
     2521 aagttccaat aaataagaag aatggtccta ttataaataa gtaagaagag ccaattttaa
     2581 tgacatcttt atcagtattg aatagagcaa ttagattttc cctaaatagc aaaattaaag
     2641 caataactgt aactgctaaa actaaggtca tttttataga ttctcgaatg ccttttttaa
     2701 ctctttcatt ttctccagca cctatgtttt gagcaacaaa agtagaaaca gcagaaccaa
     2761 gattcataat aggtaagctt ataaaatttt ctatcctaag accagcacca aaagctgcca
     2821 tagcagatgt accataacta ttaactaaaa attgaagagc catatttcca attgaaaaca
     2881 acatttgttg aactccactt ggaagtccta atctaagtcc atctttaaat attttgttat
     2941 catatacaat tcccttgatt ttaaatttaa gcacttcatg ttttttattt aaataaatta
     3001 tacttattat aaatgatact gcctgagcca ttatagtggc aagtgcaacg ccctcaacac
     3061 ccattcttag cacgacaata aaagttaagt ctaaaactat atttagaatt gtggctatta
     3121 tcagaaaata aagtggagtt actgaatctc caagtcctct aagtattgca cttactgaat
     3181 tatatccagc agaaaataat attccactaa atattatagt aagatacaat tttgattgag
     3241 caaaaacgga ttctggtgta ttcataagct taagcatggg gccaccaaat actattccaa
     3301 gaatacttat taatatagaa ccaataaata aaagtatata tgtagtatca atagtagctt
     3361 ttaccttttt taaatctcct gagccataaa attgtgacac taaaatagaa aatccaaggc
     3421 taacacccat aagcgctgcc accaataaaa acattatagg gttagctcca gagactgccg
     3481 ccattgcttc ttttccaata aatctaccaa ctattatact gtcagctgta ttgtatagtt
     3541 gttgaaataa actaccaata agcataggca tggcaaaaaa gaatatggac tttccctcat
     3601 gacctgtagt taaatctttc accttattcc tccaaataaa aaaattatta atttattata
     3661 gtataatctt aacataaact ttatatccaa actataaata aattgtatca aaatatcata
     3721 tattttttta aaatgtaaag aatataatta taatttgaat ttaataaatc aatatttaat
     3781 ataatcgaat attaatacaa aatcaataca atatatacgt atatattgac aaaattaatt
     3841 atataaatta aaataatatt cgtaaagaaa aattcatgtt ttgtactgta taacatataa
     3901 ttttgacaat atgggtcata agtttctacc ggaataccgt aaatattctg actatgtata
     3961 ctattattta gttaattaaa tatttaatta actgaattat gaaggatacg gctcagctta
     4021 tcaactactg tgtcgttttt ttgtaaaatt taataggagg tgttgttatg caaacaacaa
     4081 acagtagtac tatgcagaaa ctttttccaa ttttgactaa taaaaatgtc gacatgaaga
     4141 aggaaataat tgcaggagta actacttttt taactatggc ttatataata gctgtaaatc
     4201 caaatatttt atctgagaca ggcatgcctg caggtgcact tgttacaggt acttgtttag
     4261 cagcagcatt tggatgtatt ttaatgggtg tagttgctaa ccttcctttt gctttagcat
     4321 caggtatggg tcttaatgca ttttttgcat atacagtagt tttacaaatg ggtgttcctt
     4381 gggaagtagc tcttacagca gtatttgtag aaggtattat ttttatagta ttatcagtaa
     4441 gtggagttcg tgaggctgtt gtaaatgcga taccaaaaaa tatgaaatta gctgttacag
     4501 gtggtatagg aatatttatt gcacttatag gtctagttaa cagtggaatt gttattggag
     4561 accaagccac tcttatcaaa atgggtagat ttacaccagc agtaataata acttgtgtag
     4621 gattaataat tattgctgta ttagataaaa aaagagttaa aggttctata ctttttggaa
     4681 tagtagtgag ttcattactt gcttgggcat ttgcttttat aaatccagag tatgcacaaa
     4741 aattaggtat atatttacct ggtggattat ttaaattcga aagtttagca ccaatagcag
     4801 gtaaaataga tttaggatat gtactacatc caacaaatat aggtggtttt ttagtagtag
     4861 tttgtacatt tttatttgtt gatttttttg atacagtagg tacattagtt ggtgtttgtt
     4921 ctaaagcaaa catgttagat gaaaaaggga atgttcctaa tgtaggtaga gccttactta
     4981 cagatgcggt tgcaactaca gttggtgcag gacttggagt atctacagtt acaacttatg
     5041 ttgagagttc aacaggagtt atcgcaggtg gaagaactgg atggacagca ataacagttg
     5101 gaattttatt cttagctgca atgtttttct ctcctgtatt tatagcaatt ccatcatgtg
     5161 ctacagcacc agctttaata tatgttggat atttaatgct tggtacagtt aaggatatag
     5221 agtttgataa tataactgaa ggtgttccag cttttgttac tattgcttgt atggcattaa
     5281 catatagtat aggtgatggt ttaactttag gtatattaac ttatgttttc gtaaatatat
     5341 tttataatat atttggagct aaaaaggcag aagacaaaaa acatgtttct gtagtaatga
     5401 ttgttctggc aatattattt ataataaaac tttggctact ataataggta ttatttaaaa
     5461 ttttaattta atataaaata aagggctgta atttattatc aattgtgatg ataaactaca
     5521 gctcttttgt atttgttgta tttttgtatt tattgtatta tttaataatg tctattagtt
     5581 ctccattttg taaagtttta ggtgtaatta ctatattgaa ctctttttgc aaatctttta
     5641 taatatctaa ttcttttttt gttattattg agattgtgtt accacttcga tttcctctag
     5701 cagttcgacc acatctatgc aggtattcat ttttactttt tggaaaatcc aagttaaaaa
     5761 catgacttac atccacaata tctagtccac gagcagataa atcagttgta attaaaatct
     5821 ttgctttacc aagtttaaat ttatttattg cattctttct atcttctttt tccatatttc
     5881 caaaaattcc tattgctttg taattatgat aatttagttt tgatactagg acttctatat
     5941 ttttttcatt atttacaaat acaatagctt tttttggatt tgtagctgct aatgcctttc
     6001 taagaaaagt aaatttatcc cttatctcac ctaataaata tgagtgattg atgttaggat
     6061 ttatttgtga tttttccttt gtttttatta tttcaaactc cttcataagt ttatcacaaa
     6121 tttttatagt gctatcagta agacttgcag agcatcctat aatttgtcta tctcttaacg
     6181 ttgttcttat tatgtcttct atacaagtta tattttttcc attcaataga ttgtccactt
     6241 catctaagat aatagttttt atattatgtg attttagttt cttttgtttt atcaagtcta
     6301 aaactcttcc acaagagcca attactatgt gtggttttac tgcttttata ttttttattt
     6361 gtttttgtat attgacctcc ccaattaaag ctaaagaagt aacggagagt tctgcatttt
     6421 tagccaataa ttcaacctgg tttgtaatct gcattactaa ttcatgcgta ggtgcaagta
     6481 taagagcttg tgtttctctt tttgatgtat caattttttc aaatataggt aaaaggtatg
     6541 ctagtgtttt tcctgttcca gtctgtgaat taatcaataa atccttattt tgaattatat
     6601 tccctataac aagtgactga acttctgttg gagaagttat gtcttgtttt ttgagtccat
     6661 ctattagagt ggaacttatt tttaattgtt caaatgtatt catattttac tccttatatt
     6721 ttaataatta tagtcaacta ttttttatta tacattgttt attcaaatcg aactatatat
     6781 tcttttataa ttatgtgtaa tttgaaagta aatatcaatt atatttatac ctttatattt
     6841 ctgatacctt tgcattttat agatttctaa aataaacaaa taaaagttgt aattgtttga
     6901 tatttgttat atattatata taacaaatat caaaactata atatggaggg aaattatgtt
     6961 aaaagtaatc aatgtatcta aatcatataa aaataaaaaa gtagtaagta gtgtctcatt
     7021 tgatgtaaat gatggagagc tttttgggtt tataggacat aatggagcag gtaaaactac
     7081 tactattaaa gcaattgttg gaatacacga ttttgaagag ggagaggtac taataaattc
     7141 taaatctata aaaaaacagc ctgttgaatg taaaaaggaa atggcatata tacctgataa
     7201 tccagattta tacgagtcat taactggtat acaatacctt aattttatag ctgacatatt
     7261 tgaagttgcc aaagataaaa gagaagagtt aataaaatat tattcaaata agtttgaact
     7321 caataaagca ttaggagatt taatatcttc atattcacat ggtatgaaac aaaaattagc
     7381 tataatttcg gctttgatac acagcccaaa aatcttaatt cttgatgaac cttttgtagg
     7441 tcttgaccca aaagcttcct ttatattgaa ggaaattatg agggagtttt gtgacaaagg
     7501 tggttgtata tttttctcaa cacacgtttt agaagttgct gaaaaaattt gtgataagat
     7561 tgccataata aaagatggaa atataattgc ttatggaact acagaagaag ttaagggaag
     7621 taattcactt gaaagtattt tcatggaatt aatagagaaa taaaatgttt tttatacaat
     7681 atagtgtcta aagtgaggaa tgataaaata tgagcaatct aagtatatta ataaaaaata
     7741 atataataaa tgaatttaaa ttaaatgcgt taaaaaaagc tgacggtaga gaaaaacaaa
     7801 aaataatggg aatgatgctt tcagttgtta taatagcggg tctattaatt ttttatgtaa
     7861 cgagcttaag tctctcttta gttgatatct taaagcaaat aaatcaactg gaaatgctac
     7921 tgatatttgg ttttggatta tcaacattaa caactattgt tacatcatta tataaaacgt
     7981 catcatatct atttcaagca aaagatttag accttttgac tagtttacct ataaaagaat
     8041 ctactgtact agcaagtaag atattaatgt tggttggagc aaactattta ttttcttcaa
     8101 tatgtatgat tatacctgca gtggtttact ttttaaattc tgatgtaagt ataacttatt
     8161 tcccttattt gatattgcta tttttagctt taccattatt accgatagtt gcttcatcaa
     8221 taatttttct atttataggg cagatatcat caagaataaa atacaaaaat ttagtattaa
     8281 taataggtag cattatattg atgttgcttt ataccctact tatgtcaaga cttaattcta
     8341 tgtcagttga aatgctaaag aatagtgtgt ctatttcaga gacgattaga aaagtatatc
     8401 ctcctatata ttattttgtt gatgctctta aaacaggaag tatagtttca tttttagcat
     8461 ttatagccat ctcaataata ccatttttta tgtttgtaac tctgtttgca aaaaaattta
     8521 aagatataaa tgctaagatg agtgaaggat ataagtcaaa aaattatgaa tttaagggtc
     8581 aaaaaacttc aagaccttca aaagctttat taaaaaaaga atttaagaga tatacttctt
     8641 cgtttatata ctttttaaat tcatctgcag gtttgttatt tctaatagta ggtacaattt
     8701 taatattatt atttggagca gataaagtgg gtgagttact gaaattgaat atagatttta
     8761 atcttataaa aatacaatta ttgggagtat tcttctttat aatagtaatg aattgtacaa
     8821 catactgttc aatttctctt gaaggaaaaa atttatggat actgaaatct tctccaatag
     8881 atgaaagaga aatattctgg tcaaaagtat taatgaattt tttattgaat gccccattat
     8941 ctattttatg tctaatatta gtatctataa gattagactt tgaaattcag tttattattg
     9001 tatcaatctg tttgattgta agtttttcaa tgtttgtagc attgatggga ttattatcaa
     9061 atttattata cccaaacctt gattggaaaa atgaggtggc tgtagtaaaa agaagtgcaa
     9121 gtatgatagt tacaatgtta gtatcattag cttatgtaat tatacttgga ggtatatatg
     9181 tattacttgg aatttcgttt ttaaatatat atattatttt ggcaagtata cttactttga
     9241 tattagattt tatgatatgg agaattattt ctactaaagg agtaagaata tttaaaaatt
     9301 tataggtgta tttatgtcaa ataaagactt atctttttta gtcttgcaaa taataggtta
     9361 agtagtatac tatgtatagt gatatgaaaa aatttaggag aaaataaatg agaaaattat
     9421 ccaaaagaga aaaagatttt attcaatatg gatttttatt atttttgata tgtattacta
     9481 cttatttagt attaactact ttagatataa aactaatacc taaaattata aggctagtaa
     9541 ataagactta tatatttctt ggcatattga caattatagt atatatgata attgaatcta
     9601 ttgtaactca tttgataata aatgcagttc aaaaaacaaa agtaaaattt attggtatta
     9661 aaatggctac aatgggattt tactataact tagttactcc atttgcatct gggagtcaac
     9721 caatgcaaat atatgcactt acaaaatatg atgtaagcct tagtaaatca gtggctatag
     9781 ttactaataa aactgtagta tttcaaagta cagttactgt attttgtgga attttaattt
     9841 tgctaaataa gtcattactg atggagcaag tacattctgt gaaagtcttg ataacttttg
     9901 gaatgattat gaatgtaagt atgttgttag gtggactact aatagtattt agtccaaaac
     9961 aagtaaaaat gatagcagaa gttttgatta attttttatc taaatttaaa acatttaaat
    10021 ttttagattc aaaacgtgat agaataaatc attatattga tgattataat tattctataa
    10081 aaatatttat taaaaatgta agaatcttag ttttaagtat attacttact gtgttacaat
    10141 taatcgcata tttcagtata gtttattgtg tgtataaagc ctcaaattta agaggagttt
    10201 catatgtaca tataatgaca ttacaggtct ttttatatat ggctatatca ccaattccaa
    10261 caccaggaaa tgttggagct aatgaggtta cattttttac tatgttctcc aatataattc
    10321 caaaagaatt attggggtac tctgtactct tatatagtgg gtttgtatac tattttatat
    10381 taatagtttc aggtttattt acatttggaa cgcattatac attaaattct tggaaaaagg
    10441 aagataaagt aaattctaat ttagataagg ttattgaaaa attaaattaa taaaataatt
    10501 agggaaattc tatatataaa tatggtgttg aataagctat attatattga gatatttccc
    10561 ttttttgatt aaaattatag aaatttgaaa taataagtaa taaacagaaa aagtgatatt
    10621 gttttgaaag gagaaactat gaaacaagat aaacaaaatg aaaaacaaag tgagatttct
    10681 aagataaaac aaagcaatga taataaactt gaaatagctc aagaattaca tgtaagtaaa
    10741 aatataggga atatgcttgg atatagaata gataagaaaa aaatgaatag accaagttaa
    10801 tgaaaatgtt gaaaatggta cattttaaaa aatatatata atgaaatgtt ttattgttaa
    10861 atttaaactt attttaatgg aggaaaaagt cgaaaaatat ctaaaaagat atggatataa
    10921 aaaatattaa tatatatata ctataaactt gacaaaatca accttttaat aactagcaaa
    10981 aaatagcaaa attatataag cgttatttaa ttgtcaaaaa tgaaagctaa attgcatgtc
    11041 ctaaaaaaaa tgattgataa catttatttg tgtgctataa ttatatagta aaacaataag
    11101 tatattgcat aatgtatgca aatcgggagg agagacggac atggaagcat ctatacacac
    11161 aattgccagc aataatttat tgataatttt tgctattgta agtataactg gaataatttg
    11221 tagtaagctt agtgaaataa taaaggttcc agatgtagtg ttatatttac ttgtaggtat
    11281 tttaatagga ccatcatttt taaaatttat agatattcgt ggatttcaaa tagaaaatca
    11341 actaatactt acatttggtt ctgcatttat tttatattta ggtggaaaag aaataagttt
    11401 aaaagtattg agaaatgtga agatatctgt attcttatta gctactttag gagttgtgat
    11461 atctgctttt ataatgcaac aagtaatagg atttactttt gggataagtg caatgactgc
    11521 tttactagca ggaactataa tagcatcaac agacccagcc actcttgtac ctatatttaa
    11581 tcaggtaaag ataaaggata gggtaaaaca aactgtaata agtgaatcag cttttaatga
    11641 tgcaacagga gctatactaa catcagcagt gttggctgta attttgtcaa ataaattttc
    11701 attaggtgaa aatatttatg aactggggac aatggttatt gtcggagttt tagttggttt
    11761 aattacagga atactgcttt tgaaattagt taatgataaa ccttatggaa tatttaaaga
    11821 ttttgcacca ataatatctg ttatttcagt tgtagttgca tatgaattat ctacaaaatt
    11881 aggtggaagt ggatatatgt cttgctttat tgtaggtata ataactggta acaagaaaaa
    11941 ctttaaaatt tggttaagtc aaaaatctta tgatgcagat ttttatgttg ctgaaacttt
    12001 aggtactatt tgtcgtatgg caatatttat aatattgggt agccaagtta atttggctca
    12061 gttaagtaaa tattttatgc catctgtaat tacagtatta gtattaatgt ttatagcaag
    12121 accactttgc gttttagttt gtacacttgt agacagggaa gcaaaatgga gtaaaagtga
    12181 aatattattt atgatgtggg taagggaaac aggcgtaata ccagcagcac tttgtggtat
    12241 tatttcagca atgaaagttc ctggatacga agtgatttca tctgtagtat tcatgactat
    12301 actaattaca ttagtaatac aaggaagtac tacaaaatta gtagctaaaa aacttggatt
    12361 attagaagaa gaagtgataa atataagtga aaaagtatca actttttaaa gttttgcttt
    12421 aaaatagtac ctgttaatgg ctattttaat attgtctaat gatgattatt gaaatagtca
    12481 tttttttatg tataagtaat ttacagaatt tacatattag acatatttat tatcaaaatt
    12541 tgttgaagct atgatataat tagttgtatt taaaataaga atagcaaata agggaggaaa
    12601 tttatgttta cggttatgga tattgtacag ccagatacag tagaagaagc gtactcaatt
    12661 ttaaataaaa gaaaaactaa ccaagtaatt ggtggaagtg cttttttaag aatggggaaa
    12721 aaaagaatag gaacaggaat agaattatct aaattaaatt tagattatat aaaagagtat
    12781 gaagattacg ttgagattgg ttctatgact acttttagaa cattagaaac aagttccata
    12841 ataaaaaata attttggaag aataatagaa gattcagtta aaaatataat aggagttcag
    12901 tttagaaatg tagtaacagt tggtgcaaca gtattttcta aatatggttt ttctgacttg
    12961 atagtagcat tactttcatt agatacagaa gtagaattat ataatattgg gagaattagt
    13021 cttgaagagt ttctaaatag agattatgag aaagatttac ttattaagat atacataaag
    13081 aagacaaata agaatgcttc ttataaatca cttagaaatg caaagagtga ttatccaatt
    13141 ctaaatgtat ctgtatcaaa acatatggaa caatttaagt tatgtgtagg agcaagaccg
    13201 cagaaagcta cgattgcaaa acaagctagt gaatttctat ctaacaatga aatcaatgaa
    13261 attaatatag ataaagcagt agaaatagca tcagaagaac taacttttgg ttctaacatg
    13321 agagcatcta gggagtatag aaaagctatg agtaaagtac ttttaaaaag agctataatg
    13381 gaggttattt aatgttagta aagattaata taaatgggaa gaaaaaaagt gttgatatag
    13441 aaccagaaga atatctggtt gatactttaa gaaaagttgg taatttaagt gtgaaaagag
    13501 gttgtgacac aggctgttgt ggtttatgta cagttttaat tgacaagaaa cctacattat
    13561 cctgtgcaac actgacattg agagctttag ataaagaaat aactacaatt gaaggtttag
    13621 aaaatgaagt taaagaattt agtgaagttt tggtaaaaga aggagctgag caatgtggtt
    13681 tctgttctcc tggctttata cttactgtac ttgcaatgaa ggatgagctt gaaaatccta
    13741 cagatgatga aataaagcat tatcttacag gaaatctatg tagatgtaca gggtatatgg
    13801 gacagttaag agctatcaaa acttatctgg aggtaaaata gaacatgaat atagttggaa
    13861 aaggaatcaa gaaaatagat ggaatgagta tcacaacagg aaagcctgta tatacagatg
    13921 atttatcagc aaaagatgct ttggtggtaa agatacttag aagtcctcac gcttatgcaa
    13981 aaataaaaga tatagagaca tcaaaggcag aaatggttga tggtgttgaa tgtgttttaa
    14041 catataaaga tgtaccaaaa tctcgattta cacttgctgg tcaaacatat ccagagccat
    14101 ctccatatga tagattaatt cttgaagatg ttgtaagata tgtaggtgac gaagtagcta
    14161 tagtggcagc tatagatgaa aaaactgcaa ttaaagcaat gaatcttatc aaagtaaagt
    14221 atgaagtact tacacctgtt ttggattttg aagaggcaat aggaaataaa actatggtac
    14281 atgatgaaga tagacattgt aactttgata taggtatgca aagagaaaaa aatatagtat
    14341 cccatcatga ttatacaaaa ggtgatgtag aaaaagtatt aagtaattgt gatgtagtga
    14401 ttgaagaaac ttattatact caagctcaag cacatgcaat gatggagacg tatagggcat
    14461 acaattattt agaccatatg ggaagattgg ttgtagtaag ttcaactcaa ataccatttc
    14521 atgtaaaaag acatttatct cgtgcactag aaataccagc tagcaaaatt agggttataa
    14581 aacctagaat tggtggcgga tttggtggta aacaaactgc atgtgttgag attttttctg
    14641 caattgttac tttaaaaaca gggaaaccag ctaaaataat ttatgataga aaagaaactt
    14701 ttaattgttc aacaagtaga catgcaatga gattaaaagt tagactaggt gctacaaatg
    14761 atggcataat aaaggcaata gatataaaag cactttctga tacaggagca tatggagagc
    14821 atgcttctac aactattggt ttggttggag aaaaaacttt accaatgtat aataaagttg
    14881 aagcaacaag atttattgca gatgtggtat atactaataa gatgccagca ggagcactta
    14941 gagggtatgg agcatcacaa ggatgttttg ctgttgaatc aactataaat atgcttgcta
    15001 ataaattaaa aatggaccca acagatttaa ggttaaaaaa tgtggtaaca gaaggtgaaa
    15061 ctacatttgc atatggtaaa actttaaata gtgtcgattt aataaaatgt ataaataaag
    15121 gcaaagaact tattggatgg aatgaaaaat atccttgtaa acatcttgat aatggaaaaa
    15181 ttagaagtgt gggtatggca attactatgc aaggttctgg tatacaaggt cttgataagt
    15241 cttcagctga aataaaattg aatgactgtg gagattatac tcttatgata ggttctactg
    15301 atatgggtac aggaagtgat acgattttag ctcaaatggc tgctgaggtt cttgatacaa
    15361 gcattgaaaa tataacagtt atatcagctg atactgactt agttccatat gacccaggtt
    15421 catatgcttc aagtactact tatgtaacag gtatggcagt agttaaggca gctcaagact
    15481 taagagaaaa aataatttct gctggagcaa ctaaactagg tgttgagaag gatgaagtag
    15541 aatttgatgg tataaaatta actagtaaaa aaggtagcac tttattattc gatatagcag
    15601 ttgattctac aattggtcca gatactaatc aattaatagg tcttgcttct catggtagcc
    15661 cagtatctcc tcctcctttt atagcaggtt ttgcagaaac tgaaattgac acagaaactg
    15721 gaaaagttga tttagtaaat tatgtagctg tagtagattg tggaacggtt ataaataaaa
    15781 atctagctaa gatacaagtt gaaggtggaa ttgttcaagg gattggaatg gcattatttg
    15841 aagaagttag atacacagaa aaaggaagca tggacacaaa tacatttatg caatacaaga
    15901 ttccagctag atgtgatatt ggaaatgtta aagtagattt tgttgaaact tatgaaccaa
    15961 ctggaccatt tggtgctaaa tctgttggag aagttgttat aaatacacct ttaccagcaa
    16021 tacaagaagc tgtgtttaat ggaattggtg taagaataaa tacactccct attacacctg
    16081 aaaaagtttt tatggaaatg aataaataat tatttatgaa aatttagact agttttacat
    16141 gttaaacaac cagttatgtc atacctgttg aaagatattt aataagtagt tattataata
    16201 ttatgaattt tacttataaa atacaaaatt aaataagggg atgatgtttt ggctggtaat
    16261 ctaaataata tgagagcagt aaataatttt agaggagata agaacatttt agaatgttta
    16321 gtcagctttg agggtcgttc aataagtcag agaaaagtaa gggtattttt taaagaaaaa
    16381 caaaatcaaa tagaaattga ttttgcagaa gaggaaattt ctaaattggt tgaaaatgtt
    16441 gttttaaata catcatatca agaaatgtta tatgatgaaa tagagaaaca actggaaatt
    16501 gattgtatag gtacttggat gatattatct aaattaaaag atggtagtag agttcactga
    16561 ttttaaaata aattattaga gcctaatttt aaggctcttt tttgctgttt ttaattaaca
    16621 atagaaaatt tatctttagt ttgtatataa ttttaatatc atatattcta tatatataaa
    16681 attgaatttg tatgtattat gttgtataat ataaaatgaa ttaggaaaat agttcgctaa
    16741 aataatttgt ttttataaaa ttactgttta agtttataga ttttgtataa aataaagtta
    16801 tgttattaat ttttttagaa ataaaacttt tactaggaga cagatatgag aaaaaatagt
    16861 attaatatag cactaactgc agcaattaca gcaatctatg cagttttaac attatcattg
    16921 ggatttataa gttatggacc aatacaattt agggtagcag agattatgat gcttttggca
    16981 tttttagata aaggatatat agtaggtctt acattaggtt gttttttagc aaatgtaata
    17041 ggaccatatg gtgtacctga tataattttt ggaacattag ccacatttat aagtgcaagt
    17101 atgatttata ttactagaaa gttaggtaaa cagaataaaa gtactttagt tatagcttct
    17161 ttatggccaa ctgttataaa ttcgattgtg gttggtctaa tgttaaatgt attctttggg
    17221 cttccattaa ttctatctat gatacaagta ggttttggag aatttgtagt agtaacaatt
    17281 gtaggagtac catttttctg ctttttaatg aaaaaatata aaaatgtcat taatattaaa
    17341 ttttaaatag tgtatagtaa tttaattaat tgagagtatt attagtgaaa agaggtgttt
    17401 atttgtcgaa ggtaaaaaga ttgactgatg tttggatata tattaatgat aagcaaaagt
    17461 ttacaataaa agagttgtca gaagaattta atctttcagc taaaacaata caacgatatt
    17521 taaaagaatt aaataaaatg ggacttccaa ttcaagcaga acaaggtaga aatggaggtt
    17581 atagggtgct aaataatagc tatatacctc ctgttatatt tacagaaaaa gaagttatga
    17641 ttatactatt tgcacttaag tcacttcaga tttataatta taagttaatg gaaatagaaa
    17701 ttaattctat aatgagaaaa gtaagttatg aacgtaaaag cagtataaaa gtaggtatag
    17761 aaaatattaa aagatacatt ggctttgtag ctaatgatac taatgatgga gattttaaga
    17821 gtagtaatgt aactgagttt tttagagctt cttcagaatc tctaatttta aatattaagt
    17881 ataagtgtgg taatcagatt ttggaaaaaa acgtatgccc tataggtata tatttaaata
    17941 agggagcatg gttttcacca gcatatgatt gtaaaagtga taaaataata ttagttcata
    18001 tagataatat aattgatata aaaagaacag gagaaagtaa aaaaatacat ataaacttgg
    18061 aagaatggtt acatgaagta tataacaatt tatatggaaa tagttcaact actaaaaaat
    18121 ttggtgaaat tatttatcta aatgtattat taactaaaga aggtgtttct aaaataaagg
    18181 acagttcttg gaatttagat atggagctaa atgaagatgg tagtggaata attagtacat
    18241 tcataaaggt tgaagatata gattgttatg cttcgatttt attttttatt ggaaataatg
    18301 ctaaggttat agagccaaaa tttttgaata agctacttta tgataaggcc aatgagttaa
    18361 gatattttta tgaagaaaat atggtataat atttagaaat gttgaaatta aataattatt
    18421 aaggagatat acgttataat ggaaaatttt aataagaatg ctaaaataat tggtattgga
    18481 gctgaaggta ttaatataat aaatgaagta gaagaaaaaa taaaagcaaa tatggatata
    18541 gaaaaaataa acataaatca agagattgaa aaagaatatg ttagaagtct tttagatggt
    18601 gtagatatat tatttttgat atattcatct gaagataaac atattagaga tattataaaa
    18661 gctgtttcat atatgtcaaa cgaaagaaga gttctatcta taggaatgga ttgttcagag
    18721 aaggaaaata aagaagattt agagcttggg agagagttta aaatcaataa tgatagtata
    18781 tttaaatttg ttgatttaat gaatatcatg gtagagtcta tttctgattc ttgcatgata
    18841 aatatagata ttactgattt aaaagaagct attgtaggag ataaaggaat taagtattct
    18901 tttgaagagt ttgaagatac aaagtcatat agcgagatag ctgacatttt atttgatagg
    18961 atggaatata ttggtgagga atttataagt aagaaaggaa ttgtatttgt tgaaggaagt
    19021 ccagaatttt ctataatgga attgaatgat ttaataagta atattcagag caaggtagaa
    19081 gaaagctatg aagtaatatt ttctttatat ataaaggaaa atttaaatgg aaatattaga
    19141 gtaggcttat tgtataatta gtatatttta gatattaagg agagtgtata tgtctgaaaa
    19201 tataagaggt acagagtatt ggttaatgga agaatttttt tatcaggaaa cagacacacc
    19261 acagattttt agagaagaaa gcataattgc acttggattt gatataaaaa taaatttaaa
    19321 aaaagtattc agtatgggga aaaaatcaga aaagtatatt aatgagaatt gtaatgataa
    19381 agattttata aaaaagttta tgtcgattaa aaaaggagat tattttttat ataaagcata
    19441 tcaaaatata gaagaaaaag ttaaatgtaa tgtgtctatt ggcatagttg aagaagattt
    19501 tgaaaatgga tatgaattaa gtcatatttt agggcataca ctaccagtaa aatggatgca
    19561 taattttgat acagtttcaa attgtaaagt atatataagt gaattttata aattaaataa
    19621 taatgatatt agctcatatt tagaaattat taagtcacaa gataagaaat tattgagaaa
    19681 aagaatagaa gaaagtgaaa ataataaatg gtatttaaaa aactattatt ataaaaatgt
    19741 agataagtgt gtagatgatg aagaattatt tattcagccc attaatctag aacaattaga
    19801 aagcctaaaa aatataaaga cagatgatta tattttattg tataatagcg agaaagtaat
    19861 ttgtgaaaat gaccatacaa tgaagagtct atttggcgta tgtcaagtta tggaagggtt
    19921 cgataaagag aaagtaagtg ctttggaggg tggatatttt tttcctgtta gatggataga
    19981 gtatgaaaag gagaatatag acggaaatgc atgggttata tttgaaaata atagtatagt
    20041 tgaaaagtat gtaaaaagat ttactaataa aatggcatta aatactatac tttatggacc
    20101 accaggaact ggtaaaacat acaatacaaa acagatggtt tacaatctag taagtgaaac
    20161 cagtctaaga aacagatact atacaggtta cttagattat aaaaacaatg tagaattttg
    20221 tacatttcat caatcatatg gatatgagga atttatagag ggtcttaagt ctgatggtga
    20281 aggcaatttt aagccagaag atgggatatt aaaggatata tctatagaag catgttataa
    20341 tgcattgaaa tttgaaaaaa agatgagctt tgagttggaa aaagatagct tgactttaga
    20401 aactataaaa gacaggaaaa agaaattagt attagaaaat atagaatata gtgagagttt
    20461 taattttgaa gaatcagaaa actatgtttt aataatagat gaaattaata gagggaatgt
    20521 atctaaaata tttggtgagc taataacatt attggaagat gataaaagac ttactaaatc
    20581 aaatcaaact attgtcaaac taccatattc aaaggaaaaa ttttctctac ctccaaattt
    20641 gtatatagtt ggaactatga acacatcaga taaatcaata gcacttttag atatagcttt
    20701 aagaagaagg tttaattttg aagaaattat gccagattat gatttattgt ctattgtaga
    20761 tggtatagat attagaaaaa tgctatatac aatcaataaa aggatagagt ttttatatga
    20821 tagagaccat gttattggac aagcttatct acttgctgta gaaaatatta atgatatagt
    20881 agtagtattt agaagtaaaa taataccact tcttcaagag tatttttatt atgattcaga
    20941 aaaagtaggt ttgattttag gaggaattgg aagaaatgaa aaagataaat acattgttta
    21001 taaagaaaaa cttatagctt ctgagttatt taaaaataat aatgcctcaa taatggagag
    21061 taaagttaac tattgtataa aacaaaacat atctagtgag gagctaaaaa atatatatga
    21121 gtaaaaatat atatgttaag gaaacctatg aatggataag ggtaggtaat ggtgaaaatg
    21181 agcttacaga aattgaatat gaaaaattgc ttaagcatct agagaacaat aatgatgtat
    21241 taaaaagtaa tataatagat attaaataca aaaaacttag atttataaac tatgtaggca
    21301 tcatatgttt tgaaaatgta atacttgaaa tacttcctaa attgtcatta agtgataatc
    21361 ttgtaaaaga tagagagata ctattacaga tgctttctat atgtaataaa attccaatta
    21421 caatgaatga aaaaataaga ttgagtttga aaaattataa tctcttaaat ttttttgtta
    21481 tgtatttcat tgagagtatg caaacacaga tgaaaaaagg tatttatttt gaatatataa
    21541 ataaaataga gaacttaaat gttatgaggg gtaaaatatt attaagtaca tatgcaaaag
    21601 aaaaaggcat ttctccaatg aaaataagat gtgaatatga tgagtatagt gaaaataatt
    21661 tcttgaatca agttcttaaa aaagcatgta tatctatttt atgtagaata aatgacaatt
    21721 caattcaagg caagattaaa aaaattttaa gctattttca aaatgtagat ttaatttata
    21781 tagatagaaa aaaactgttg gattataaat tttataaaaa caatgataga tttaaagatt
    21841 gttatttact agctagactt ctacttttaa atttgtctat ggataatagt caaaataatc
    21901 aagaggcatt ttctatatta tttgaaataa atactttgta tgaagaatat ataggaattt
    21961 taatcaaaag tatatgggac aattcattta gagaaacata tatacaagat aagagtaaat
    22021 ttcttttgaa aaatgaacaa actggtaaga aaaactttaa tttaagaccg gatatagttt
    22081 tatatgactt aaaaaatgaa tatgaaatta taattgacac taaatggaaa gctattgaag
    22141 tagattcaaa tgttttttat aggtcaagtg atatatacca gatgtatgca tatataacag
    22201 catatgaaaa tgcaaaaaga tgtatattat tatatccttg tattcaaaaa gataagaatt
    22261 atagttcctg gaaattatca gaatcattta agggtaagtt tatagaagca aaaactgtga
    22321 ggttagatga tataaaaaac acaaaaaatg atttaaaaaa gataattttt aattataaat
    22381 tttaaaaata agaattttaa aatttataaa agtaatttta tataggtata aaaattacga
    22441 gtagtataaa aaatttaata aggatttaaa ttaaaaattt taaaaattat ttccatataa
    22501 aatatggcat tgtaattgct tatttaatag aggatttttg taaaatgaag aaagtatatc
    22561 tatcaaatta aaactaagta gatatacttt ttattaagtt ttgttttaaa ataatattat
    22621 taaattataa ctaagctttt ctgttatgat ataattaaat agataatgtg aatgattatt
    22681 atatagaata cttatttgga gttgatattt tatggacaaa cacagtgatt cagtaatgta
    22741 tggtggaatg gaagtatata atatttgggg aacaacaaca gtagactcca taattggaga
    22801 gtctgatgta atgcgtgctc ttaagaatag aatttgtaaa attggaaata gtgattctac
    22861 tgtagctata actggagaaa gtggcactgg aaaagaatta atagcaagag ccattcatct
    22921 cgcaggaaac agagggaata aaacattcgt tgctataaac tgtgctgcta taccagaacc
    22981 tttactagaa agtgaacttt ttggatatac aaaaggagct tttagtggag cagattcaaa
    23041 aggtaaaatt ggtaagtttg aattggccaa tggaggggtt gtatttttag atgagatagg
    23101 agatatgcca attcaactac aatcaaagtt attgagggta ttacaggaaa agaagtttac
    23161 gagaataggt tcaaatgaac taattgatat agatgttaga atcatatcag ctactaatag
    23221 agatttattt gagttggtta aggaaaataa atttagagaa gacttatact atagattgaa
    23281 tgtaatacct ttagaagtgc ctccacttag agaaagagga gacgatatac aaatattaat
    23341 aaacaatttt atagacaaat attcgagaaa gatgaagaaa aacgtgtacc atatagagcc
    23401 agatgtggaa caaatgttgc ttaagtatcc ttggccagga aatattagag agttggaaaa
    23461 tactatagaa ctggcattaa accttcttga ggaagatgga ataatacata aaggaataat
    23521 aaatagaaag atacttgaat attttaagtt aaataatata aatataaagt tacttgagga
    23581 aagtgactat gagataagta tggaacaaga catacttaca cttgaagagt ttgaaagagc
    23641 ctatataaag aaagtgttaa agttttacgg aaatgatact aagtctaaaa aactggctgc
    23701 caaaaaactt ggaatatcac tagctacatt gtacagaaaa atagatgtat aataattagg
    23761 ctttttattc tcaattctaa aatttgaaat tataaaattg ataaaaaaca cttggaaaac
    23821 t
//
LOCUS       DAEOTL010000058        23733 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEOTL010000058 DAEOTL010000000
VERSION     DAEOTL010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.058"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..486
                     /locus_tag="KRH82_002654"
     CDS             <1..486
                     /locus_tag="KRH82_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8655924.1"
                     /translation="LGTCPSMTVRENLSLALNKGKLLNLRKCLRYKRDFLENLLEGVS
                     LDLKKYLDVQVKFLSGGQRQSLSLIMSCLTNPSVLLLDEHTAALDPKTSNEVIELTDK
                     IVREKNITTLMVTHNLKHALHYGDRLIMLHKGEVVLDVKGKEKEQLTVEEILEKFEYA
                     V"
     gene            617..1639
                     /locus_tag="KRH82_002655"
     CDS             617..1639
                     /locus_tag="KRH82_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655925.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(1803..2360)
                     /locus_tag="KRH82_002656"
     CDS             complement(1803..2360)
                     /locus_tag="KRH82_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBG8655926.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(2366..3442)
                     /locus_tag="KRH82_002657"
     CDS             complement(2366..3442)
                     /locus_tag="KRH82_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBG8655927.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLNFPQEYLFCFRYNYNKKE"
     gene            complement(3443..4126)
                     /gene="modB"
                     /locus_tag="KRH82_002658"
     CDS             complement(3443..4126)
                     /gene="modB"
                     /locus_tag="KRH82_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBG8655928.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(4275..5087)
                     /gene="modA"
                     /locus_tag="KRH82_002659"
     CDS             complement(4275..5087)
                     /gene="modA"
                     /locus_tag="KRH82_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8655929.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            5280..6209
                     /locus_tag="KRH82_002660"
     CDS             5280..6209
                     /locus_tag="KRH82_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8655930.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(6370..6819)
                     /locus_tag="KRH82_002661"
     CDS             complement(6370..6819)
                     /locus_tag="KRH82_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655931.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7022..8002)
                     /locus_tag="KRH82_002662"
     CDS             complement(7022..8002)
                     /locus_tag="KRH82_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8655932.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(8207..9067)
                     /locus_tag="KRH82_002663"
     CDS             complement(8207..9067)
                     /locus_tag="KRH82_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBG8655933.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(9384..10712)
                     /locus_tag="KRH82_002664"
     CDS             complement(9384..10712)
                     /locus_tag="KRH82_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBG8655934.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(10860..11189)
                     /locus_tag="KRH82_002665"
     CDS             complement(10860..11189)
                     /locus_tag="KRH82_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8655935.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKYHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(11213..12502)
                     /locus_tag="KRH82_002666"
     CDS             complement(11213..12502)
                     /locus_tag="KRH82_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8655936.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(12518..12844)
                     /locus_tag="KRH82_002667"
     CDS             complement(12518..12844)
                     /locus_tag="KRH82_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8655937.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(12979..13608)
                     /locus_tag="KRH82_002668"
     CDS             complement(12979..13608)
                     /locus_tag="KRH82_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655938.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(13823..16480)
                     /locus_tag="KRH82_002669"
     CDS             complement(13823..16480)
                     /locus_tag="KRH82_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8655939.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(16839..17783)
                     /locus_tag="KRH82_002670"
     CDS             complement(16839..17783)
                     /locus_tag="KRH82_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655940.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKLLSWIEVSDGHFVYSSKSDINKYQQNLKVV"
     gene            complement(17776..18801)
                     /locus_tag="KRH82_002671"
     CDS             complement(17776..18801)
                     /locus_tag="KRH82_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8655941.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(18876..20444)
                     /locus_tag="KRH82_002672"
     CDS             complement(18876..20444)
                     /locus_tag="KRH82_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655942.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(20557..21468)
                     /locus_tag="KRH82_002673"
     CDS             complement(20557..21468)
                     /locus_tag="KRH82_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655943.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(21452..22438)
                     /locus_tag="KRH82_002674"
     CDS             complement(21452..22438)
                     /locus_tag="KRH82_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8655944.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            22798..23199
                     /locus_tag="KRH82_002675"
     CDS             22798..23199
                     /locus_tag="KRH82_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8655945.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            23202..23600
                     /locus_tag="KRH82_002676"
     CDS             23202..23600
                     /locus_tag="KRH82_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBG8655946.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
BASE COUNT         7732 a         4066 c         2686 g         9249 t
ORIGIN      
        1 cttggaactt gcccttctat gactgttaga gaaaacttgt ctttagctct taacaaagga
       61 aaactattaa atctaagaaa atgtcttcgt tacaaaagag atttcttaga aaatttattg
      121 gaaggtgtat ctcttgattt aaaaaaatac cttgatgttc aagtaaaatt tttatcagga
      181 ggtcaaagac aatcattatc actaattatg tcgtgcttaa caaatccatc agttttatta
      241 cttgatgaac atacagcagc acttgaccca aaaacatcaa atgaagtaat agagttaaca
      301 gataaaatcg taagagaaaa aaatataact acacttatgg ttactcacaa cttaaaacac
      361 gctcttcatt atggtgatag attgataatg cttcataagg gtgaagttgt attagatgta
      421 aaaggtaaag aaaaagaaca attaacagtt gaagaaatct tagaaaaatt tgaatatgca
      481 gtttaaaata atatatctat tgtattaaac tcggctttaa aataaagtta aaattacaat
      541 aattatggtt actttgtaat aattcatatg aatatatgaa catatataat aataaatttt
      601 tgagggggat ataaaaatga ttaataaaaa aagattggca agtttgattt tagctggtgc
      661 tcttagtata tctatgctta cagggtgttc acaaggagga gactctggta attcaaaaca
      721 agaaagtaat tctaaaggta aagaagttaa aaaaattggt ataactcaac tggttgaaca
      781 tccagcatta gatgccacta gaacaggttt tgtaaaagca ttagaaaaga acggatttaa
      841 agatggagaa aatattgata tagacttcca aaatgctcaa aatgacatgc ctactacaca
      901 aagtattgcg agtaaatttg catctgataa gaaggactta atatttgcta tatctactcc
      961 atcagctcag gcagcattta atgctactaa agatatacct atacttatta ctgctgtgag
     1021 tgaccctgtt gctgctggat tagttaaaac tcttgaaaag ccaggcacaa atgtatctgg
     1081 aacatcagat tttgtttctg tagacaaagg tttagaactt cttaaaatat ttgctcctaa
     1141 ggcaaaaact ataggagtta tgtacaatac tagtgaagta aattccaaag tccaagttga
     1201 tgctttaaaa gaatatgcat ctaaaaatgg atttaaagtt gttgaaaaag gtataactac
     1261 ttcaaatgaa gttaaccaag gtatttctag tttagttggc aaaatagacg tattatatgt
     1321 tcctacagat aacttagtgg cttcttctat gcctatagtc tctaaaatag ctactgagaa
     1381 taaaatacct gttatagcag ctgaatctgg gccagttgaa aaaggtgctc ttgcttgtca
     1441 aggtatcaac tacgaaaaac taggttacaa aacaggtgaa atggcagtta aaattttaaa
     1501 tggtgaatca gtatctgata tgcctgtggc tacatcagat gatacagata tcattgttaa
     1561 tgaagatata ttaaaagctt taggtatgga aaaaccttct aatgaaaata tttcttatgt
     1621 aaagactaaa caagaataga aagatatttt ctatatacga ttaatatgcc tgtttctata
     1681 aattaattta tagaaacagg catatatttt tattttaatg tattatctat ttaaagatta
     1741 tatttaaatg ctcttaattt gtttgtataa attttacttg tataaacttt atacaatcat
     1801 atttattctt ctattttctt tattactcta catggatttc caacagctac agtatttggt
     1861 ggtatatctt ttgtgactac acttcctgca cctattacta cattatcacc tatagtaatt
     1921 cctggtgtta tgattactcc cccacctatc catacattat cacctatttt tacaggagaa
     1981 ccatactcta tgcctgaatt tctaagttgt gcatcaattg gatgataggc tgtatagatt
     2041 tgaacgtttg gagctaacat tacattgtca cctatttcaa ttttacatac atctaaaaaa
     2101 atacaatcat aatttgcaaa gaaattttcg cctacatgta tgttatatcc ataatcacac
     2161 ctaatgtttt gttctacatt tatttgcttg ccaactgaac caaatagttg tcttaaaata
     2221 tcttctcttt tttcatattc atcctctaaa gtattattaa acaatctagt taatttttta
     2281 caatactctc tttcttttac taacaattca tcatttgcat agtatccttt cccagacaac
     2341 attttttctt tttcagtcat atagtttact cctttttgtt ataattgtat ctaaagcaaa
     2401 ataaatattc ctgtggaaaa tttaaatata ttctgtcacc tttcttaaat ctcattttac
     2461 ttttttccaa ttctatttga ataggtacac attcgttaga taaatcagtt tttctaacat
     2521 atatagtata tgtaaaagga ttttctacaa tgttaatcaa ttcgaaacat aacttttcat
     2581 ttaaatcttc attagaatcc aagaccttaa tatgatgctc cctgattccc acatattcta
     2641 tattatcacc tatttctcta tttaatgtca actcgcatcc ccagtctgta gcataaatag
     2701 tatttttatc cagtctattt aatttggata tatttttaca ccctgttatc ttagcttcta
     2761 taaggtactt tggagattca aagagctctt ttttaggtct ctttggaaga ccttctcctt
     2821 tgttgtacac tataatatca tcacaaactc ggtaagcttc ttcaatatca tgagtaacaa
     2881 atagtatatc tcccttgtaa tcttttaaca tattcataag ttctttttcc atattacttc
     2941 ttaaatgatg gtccaatgct gagaaaggtt catctaaaag taatatatct ggagatgttg
     3001 ccaatgctct agctagtgct accctttgtt gttgaccacc agataattgc caagggtatc
     3061 tcccctcaaa cccatttaat ttaagtatat ctaagtacct tgctactatt tccttttttt
     3121 cactcttact tagttttaaa agcccaagtt ctatattttg acttacagtc atatgtggaa
     3181 acaaagcata gttttgaaat aaaaatccta cctttctatc ttgtgttgat aaatttatct
     3241 tcttttcaga atcaaataga actctatcat ttaatacaat tttacctctt gttggtttct
     3301 caagccctgc tatacatttt aatgtcatac tttttccaga accagattct cccaaaaacc
     3361 ccagagtacc tttttcttgt ttaatttcta cctttagttt aaaagaggat aaatcttttt
     3421 caatatccac gtataagctc aactatccac acctctttcc tataattttc tgctgaaatt
     3481 ccgaccaata atttagtaat aaaatcattg ctatagatat tgctacaata atcataaccc
     3541 acatcatagc tttattcata tctccgcctt caacagcaaa aaatatagct attggcatag
     3601 tttgagtttt tccaggtata tttccagcta tcataagtgt agcaccaaat tctccaagag
     3661 ctctggcaaa cgacagcacc aatccaccaa ttattccagg ccatgctaat ggaactgcaa
     3721 tcttaaaaaa tactttccat tcattaagac ctaatgttct agcagctgac aacatattat
     3781 tatcaatctg ttcaaaagct gaccttgaag ttctatacat cataggaaaa gacaccacta
     3841 ctgctgaaat tacagttgct gtccaactaa atattaaagt cctatcgaaa tttaataaaa
     3901 actttcctat aaatccattc ttcccacata gtaataataa aaagaaacct acaactgttg
     3961 gtggcaaaat tagtggaagt gtaaatagtc catctataag acccttccac ttacctctat
     4021 agttagccat aatatatgac acaaatattc ctattacaaa agttattatt gttgacaaaa
     4081 tagatgtctt aagtgatatc cataagggtg accaatctgt tcccatcttt ccctccttaa
     4141 ttttaaatgg aaatagtgaa actaataact ctattaattt cactatttcc attttattat
     4201 aatacacaat tattttcaat tttcatttat ttatatataa tttatactta attacacata
     4261 atttatttct aagtttattc tactttttta tatccaaatt cttcaaaaat cttttgtcct
     4321 gactcactta ataaaaattc ttcaaatttc ttagcagcat ctacgttttt actagcttta
     4381 attactgaaa ctggatatgt aataggcgaa tgagtttttt cgtctgtttt ttcaactact
     4441 tttatcttat cattattgac agtatcactg aagtaaacga atccaacatc agcatttcct
     4501 gattgcaccc atgctaaaac ttcttttaca tcttttgcaa atactagctt atcttttaac
     4561 ttatctttta aatttaaatt agttaacacc tcatctgcat acttaccagc tggaacactt
     4621 tcagcttcac caacagcaat tttcttcact ttatctgtag tcaaatcttt catacctgat
     4681 acactactgt cagcagaaga aataagaact aaatcatttt ttactaaatc tttcatagta
     4741 tcagaaacta ataacttctc ttcatccaaa gctttcattt gtttttgacc tgctgaaata
     4801 aataaatcac aaggtgctcc ttgttctatt tgttgttgta atgagcctga tgctccatag
     4861 ttaactgtaa gttttacatt tgaatcaact tttttatatt cttcttcaat ctttgccatt
     4921 gcttctttta aacttgcagc agccgatata tttaactcta ctgaatcact acttttagtt
     4981 gttttttctt gttttccatc atcttttttg tcttcattac tattgcaccc aactgtcccc
     5041 aaagttaaac atgcaactaa tcctaatatt cccaatattt ttttcataac aatctccctt
     5101 tttgtaaatt tgatacacat tttaacatgt tttattatgt tttatcatgt tttgttatat
     5161 atagtttaat tatatataca tgataataaa ttttcaagta atttatttac actactttta
     5221 aatattttgc tacattttcc tttttttaat gttaaaataa ccttatatgg aggtggatta
     5281 tggactcatt atcatctttg acacctgtcg aggtagctga attattaaag ataacaaaaa
     5341 atactgtata tgaattaatc aaaagaggtg aacttccttc ttataaagta gggaaaaaaa
     5401 taagagttga tactaaagat gttgaagaat atatcaacag ccaaaaaact ggtaaagtaa
     5461 aggatacaca tttcaacaat aaaaatatag atataaataa taatttcaaa attattattt
     5521 ctggtcaaga tgtaatatta gacattttag ctaggtctgt tgaaaaaaaa ttggatggaa
     5581 taagtacatt tcgctcttat ataggtagtt ataatgcttt gtatgagtta tataatggca
     5641 gagtttctat agcatcatcc catctatggg atttcgaaac ggatgaatat aatagcactt
     5701 ttgttaaaaa gctattgcca ggaataccat gtgtacttat aaatctagct tatagaatgc
     5761 aaggtttcta tgttgctaaa ggaaatccta aagagataac aacctgggag gatttaacaa
     5821 aaccaagtat aaccattgta aatagggaaa aaggttctgg aactagggtt ttactagatg
     5881 gtaaacttag acttctaaac tttaatggta aacatataaa aggttatgat aatgaagaat
     5941 tatcacatct tggagttgca agtactgttt ctcgtggaat agcagatgtt ggtttgggaa
     6001 atgaaaaagc tgctttacaa gtaaataata tcgactttat tcctcttcac aaagagcgct
     6061 atgatttagt tattaaaaaa gaagacttac aaaatccagt ttaccaaact ataattaaca
     6121 taataaactc tcctgagttt aaagctgaac ttcaaggtct tggcggatat gatttaactg
     6181 atactggaaa aactatagca aaagtttaag attaaaatcg caatctattt tataagattt
     6241 ataatttttc acaaaattta taacttaaac acgaaataaa ttgcgatttt agtgtctcaa
     6301 aaaatttatg tctttcattt tatcatccaa tacaaaatat aatataatta attgtgcaat
     6361 catattatat taatatatat ttacataata gtatttttct ttaatgtaga ttaacatatg
     6421 atatgtttta aacatcaatc cccttgcttt cttatatata tgtggcaaca catatgagtt
     6481 taataaatta tatacaatgt tgctttcttc ttgtattttt tcaaccaaca agttatttat
     6541 aaaattacct ttctcatttt caataatctc actccaattt atcttaactt ttaatatata
     6601 tcttcccact aggtatacac actctacaat aaataataaa aatacaatgc agtcagtacc
     6661 tgttgtctta tataaattac ccgatactaa tggctttgcg aagaaattat aaaaattcaa
     6721 agtatcaccc gtataatcaa aaagtattaa tagcactcct agaactctca atactttaat
     6781 attcaacatg tttttatctt tattattttt gtttttcata tatactacct ctcttttctt
     6841 tagatttgat tgtaatctaa tactaactct tttatttgag gtataaatga atttaattgg
     6901 tagttatttt catttttact agaaattaat tcacattact aaacaaaact tatatttaaa
     6961 cataaaaata gcctatctat cttttaataa atacaaaaat aaataagcta ctaatattca
     7021 attaactttt atcacttaaa acattactat ctataaattt aaatatttta ttgaagtata
     7081 ctgtactatc atgttcaaat ccatcaacat gaccaatacc ttctataagc cataggtctt
     7141 ttttatcatg tttaactaaa tcatacattt tcttgctatt ttgataatta caaacagtat
     7201 cttttgttcc atgtataaac agtatgggta cattagattt ctcaactgac tcatatggtt
     7261 ttacatcact gtaccaaaat ccagatttaa acttattata taaatctcca caagtcacca
     7321 cataattgat taatatatct ggtattcgtt tttctagtac tcccattcta attgcatctt
     7381 tcatttcaga ataaggagaa tccagtatat aaaaatcgac cttatcatct tttgaattta
     7441 tctctgaatg catagcagct gtccctgccc ccatggaaaa tccatgcact cctaatcttc
     7501 cttcaggaaa tttatttttt acaaatttaa ctagactatc taaatcatac ctttcataaa
     7561 gaccaaatgt gtaattatct ccaccactat taccagtatt tctttgatta taaactaata
     7621 cattataacc tttatctaaa tatctatatg ctacctttaa catttcatag taactacttc
     7681 caattccatg aacaagtatc atagtatctc ttgtctttat atttgaagtt ataaaaagac
     7741 tttcaagctt gtaattatta gaactttgta tcattaattc agatgtcttg tagtttttta
     7801 atttctccag tggtttatct tttctctcag aaaatatttt tactatatct tcgtttttta
     7861 ttaactgctc taaaccaact gaactattat acactaattt gccaaatata taagatacaa
     7921 ttaataggat taatagaaac acaattgata taattataaa tttatttctt aaactaatac
     7981 aatttttaaa actatttttc atatttattt accatacaat tttcctatat tatattttct
     8041 aagtaatagc ataattgatt atactattct tataatttct attataccta cttatttatt
     8101 aaaaatacaa attatatttt attaattttt actacttgta aattattatc ttatacaatg
     8161 aatttgtatt atataataag tatttttagg attctgttac ataatattat ttaaatattc
     8221 ttctatattt ctcttcttct tcttcagtaa acacattaaa tacaactttt aaattttttt
     8281 caggattttc ttttagccat agtctaactc tacttacagc aagattagct gcctcttttt
     8341 ttggataacc aaatacacct gtagaaattc cacaaaaaac aatatttttt atttcatcaa
     8401 tttcttttat tgtatttaaa catgatttat aacaatgaag cagttgcttt tcttgctctt
     8461 tacttggctg accaccagat acaataggtc caacagtatg tactacaaat tttgcaggta
     8521 aacaataacc tctagttatc ttagcatctc cagtatattc taaatgccct tgttttttta
     8581 ttattttgtc acaatcttct ctaagtctag gacctgcgca tgaatgtatc tcattatcca
     8641 cgcatagatg taatggttgt aaacacccta ataacttgtt atttgcagca tttactattg
     8701 catctgctct taaattcgtt atattacctc tccatatggc aatcccttcc tctacttctt
     8761 ctatatcatt tacatctact aactctcttt cttcacattc aatcaacaat aaattatgta
     8821 acatattaag tatctctgga gcaatttctt ttggtggata tacattcaaa agtcctctaa
     8881 gtatatctct aggcttaatt tcatcatttg ataaattgta tattttagaa ggaacttctt
     8941 ttgaaaaata tgcaattaaa gtgtttatat tttttcttct ttgttcgtca gttagaggct
     9001 tgatagtttt atcaaaatcc tcaaataaat ttacatcatc agcataatct ctccacttca
     9061 tagccatctc tccattcttg tattttagac ttaaaaataa ttatgtattt atgtacatat
     9121 ttatttattt ctataaacac ctacataaat cctgttaaaa gtgtaaattt tttattatgc
     9181 aacttctctg gttatttcta ttgattgata gtaaattatt gtacctaaat ttaatccaac
     9241 taacaagtaa ctaaacctac tttcctaact gcaaaataca ctatgtttgc cacttgtatc
     9301 tcatttgtaa ataaataaag tccctacaaa tacattaact aggctatgta ctaaactgta
     9361 ggaactttaa aaatatatta ttcttaatta agttttggcc aataattttt atttgcttct
     9421 attaaatcat ctagtaattc ttttgcaact gttgcactag gaactgtctt agatagcata
     9481 agtgcttgcc acaatttatt ataagacttc tcaatccaag catcaactac taatttttca
     9541 actgctaatt gttgttctat taaacctttt tggaatgttg gtattttccc tattgataat
     9601 ggttcatacc cgtcttttcc aactatacat ggaatttcaa ccatagcatc atcttgtata
     9661 ttttctatag ctccattatt ttgaactatc aataacatac gttcctgtgt attaaaagct
     9721 agagctgtag ctaaatccac tataaactct gcatgtattc ctatcttaag cccactgccc
     9781 ttagaatgtc cttgcttttc tatcaatgca catgaaccaa aaacttcttt ttctcttcca
     9841 tcaataactt cattggcacg agtataattt acatcagaat gatttacaac ataatctgga
     9901 aatagatagt actttaagta actacttggt attgtagtta aatctgtttt tactatttct
     9961 ttagtaaata aattagtttc aaaccaacta tctttcttgt catttttcat tccttcttca
    10021 ccatttataa aaccatattc ttttatatgt tctactaatt ttggtaaaag ttcatttcct
    10081 tttttatctt taattgaagt ataccaacca aagtgattta atccaaagta tcttatatcc
    10141 atatgtttac gagatttgag tcctgcaatc cttgctatat tatgttccat acctattggc
    10201 atatcacaaa tatttattac cctagaatta ggtctcaacc ttctaacagc ttccgctatt
    10261 attgatgctg gattagaata atttaacatc caacaatttg gagaatactt ttccatataa
    10321 tctatgtttt caagaacacc ttctatagac ctcattccat aagctattcc acctggtcca
    10381 caagtttctt gaccaactac cccatgtttt agaggtatct tttcatctag ttctctcatt
    10441 tcaagttttc caactcttat atgagctaaa caaaaatcta catctgtata agcctcttta
    10501 gggcatgttg ttgctaaata ctctatatta gggtcctttt cctttattag tatttcacaa
    10561 gctttagcta ccttattttg tctttcttca tcattatcat ataatttgat tgctcttaat
    10621 ggtaacctat ctaagttatc tagcaacatt aatatgattt ctggggtata tgtacttcct
    10681 cctccagcta ttactactga aaatttttcc ataataatat ctccttttct atttaaaaat
    10741 ttactgtatt tataaatata tttataaata ctagtacttt aaagtaaaag ggagttcatt
    10801 tattaaatct attaatttaa taaactatag ccaaacttca agcactattt acaagaaatt
    10861 taattcttat taattcttgg gtccatcatc tcaaatatat ctacaagttc agatactaaa
    10921 gaatgagcaa ataatgcatt tgaataatgg tcttcagagt gcacaactaa aaaatcagtc
    10981 ccactatctt cactattcat agcatttgat agtaattcta aatgatactt tgatgctgtt
    11041 tgtattttct ctgaggctga atttaaaagg tgttttgctt tattgtagtc accttttttt
    11101 atttccttaa gagacatcat tacatcactt ttagcatctc ctgcttctga tattatacta
    11161 aatacttttt cttccatttc aggtaccata tccttctcct tctaatgact tgttaaaaat
    11221 caaagctatc atcatctaat gttgtagcta attctgcatt tttatttaat tcttccttct
    11281 ccattatctt aaagaatgga taatatatca aggtcataag tattatactt gcaaatacta
    11341 atacgattgc cttccaatct aatgtcatca aaaatgctgc aacccctgga ggtaaaaaac
    11401 ctggtggttc tgcaataggt aatcctacta atcctacttt taatgccata aaattaagtg
    11461 ctccaaccaa tacaggtcca aatacaaatg gtacaaacat atatgggttc ataactattg
    11521 gtgttccaaa tattactggc tcatttattc caaatagtga tggtaaaatc acaacttttc
    11581 ccatactatt aaaactttta cacttacttc ttgacataag gtacactaat cccaaagtta
    11641 tccctgaacc agttacttgc aagaaaccat agtaaaatcc tattgtaaac acatattttg
    11701 ggtctcctcc tgctgctatc agtgttgcat tttctgccat atatgtagct gctattggca
    11761 tccatatact tgaagttatt gctgctccat gaagcccaaa gaaccataat aattgagtta
    11821 taaatagtat tatagttact gcaaaaacat tatctacact gcttatagct ggtgctaaga
    11881 aattcattat aatagctggt agtggttgac ctgagacatt tttagttatt gctgctattg
    11941 ctgtaaataa cattatacat actatcattg gagttaagtt tctaaaactt ttatttacta
    12001 cactaggtac ttcttttgga aatctaatta cgagattttt atcattcata aacttagtaa
    12061 tatcaactac taaaagtgct actaatatac ttacaaataa accttgtgca tctaaataac
    12121 ttgtatctaa tacaccatct actacttgtc cacatacaac aagttgtgca acaactgctg
    12181 tcatacctat ttctacatga ttaagattat attttttagc tagtgcctga gctataaaaa
    12241 atgctgaata tatagataat aaactcatag taaatttatt agggataagt aatgtatcca
    12301 tattttcaga taataatgtt tttgcacttc cttcaggtaa catattgttt aatgccataa
    12361 ataacatact taaagaacca acaattatta ttggggtaat acttatcata ccttctttta
    12421 tagcttgaag atgcctttgt ttttcaatct tttgtgctat tggaagaaga aatcttctta
    12481 aattattttg aagtgcttcc atttttattc cccccaatta tctattttta tataattcga
    12541 ttgccgactt cataacagaa ggagcatcca tacgaccata atgcttagta tctattaaac
    12601 caactgctat tttgtaattc ttacaagctt caactacatc atcttcctta aacctaattt
    12661 gtggtgctac aagtactaca tctgtatcat tagcttcaat gtatgatttt aaattttcaa
    12721 atgatgttgc ctctatattt atagttttag tttttaactt ttcatgctca ctacaaaaac
    12781 ttttcatctt ttccacaagt acacctgttg aagctccatt tgcacatact aataaaatat
    12841 tcataattac cctcctacaa tatctaacct cttttgtttt ctaatttttt atcagccaat
    12901 tcttactcta attcctatca gtttttactt taattcttat tattttattt taattcttag
    12961 taatatttac tctaattctt agtactgcca atgattaaac ttgaaagccg tatctataac
    13021 ttcttcttgc ttatattttt ctaatatttt taagtatctt tctttataat cattatctac
    13081 ttctttttct ggtattacta tactagcttc atttaaaaag tggaatgaat cccttcccat
    13141 ttctaatcct ctatatgtat gcttgtcaag tgccacgtcc ataacttctg gaactttacc
    13201 cattgcaaat ccttttataa ttatattttt taataaatca cttgatctat ctttctcaca
    13261 tgcacaaaga tatcttattg catgtatgaa aaataaaggt ctgtctccat ctgcatatga
    13321 atattccttt cttacttgat ttaaattatt tatgattatt acagctgatg ggtcccccat
    13381 tcctatatct tcaactgata ttgtaagtat ccttctccat agcttatctt ctaattctgg
    13441 tgatgatata tatagttcat aagcaaattc acaagcttct tccaccatat ttcttcttat
    13501 agctttttga aatgacgata ttatttcgtc tgcactaaat ccgtttcttg tagtcattct
    13561 tgcccatggg tcatttgcct ttttatctct taatatttta tcttgcatat tatttactcc
    13621 tttttattta aattttaatt atttatatta ctcatttaat aatataagca agtattatgc
    13681 cagttttttt agacacttta aaacactgtt atttcaatca tttttatcat caaaacttag
    13741 atactttgtc taagtatatt tatatgtgtc taatattaat attattttag actaaaaaaa
    13801 attaccaaat aagtttttat actcattggt aatctttttc gattatttct gcatattcta
    13861 atattaataa tatttgatag cactcttttt cattaatttc tatattatat tttttatcta
    13921 attgagatac tatatctttt attttgctta ggctcttgtg ataatcaagt gttttttctt
    13981 tatcaagctt ttcaatttct ctagtatttc caatcaaccc atctaccatg aaagctaaat
    14041 gcatcataag tccaattact ttatcgtatt tcttttctat attaaatact aaaaacaatt
    14101 catcagacac atattttata tctttaaata tcctattata attagagctt tttaaggatg
    14161 tctttaaacc ttcaactaca tcatcataac ctatacttat ctttataata ttttttaatt
    14221 tattgatatt ttcatcctta tctatatctt ttttgctaat atagtcaatt cctctaatat
    14281 taattctttg ttcattgatt actgcaacaa tattactact ttctttaagt ttcgtaatat
    14341 ttaaacttaa atctttttct gttttatatg ggacagatat aatatctatt ccatctaagt
    14401 acctactcat cttttcttct aatatttttc ttgttttatt atctacacct tctgaaacat
    14461 gtgatgctat aataattgtt ttagacagat tttctttatt ttgaatttca ttagttccaa
    14521 aatagtactt tctcgtgtta gtgatagagt tgtatacgtc atttaaaggt aatcccatat
    14581 tggccttctg aactgcttct aacacagtta atgtcgtcac cataggaatt actcttactc
    14641 cacacttttt ttctttcttt ataatttcat caaaagagtt taatgaaccc atatctgtaa
    14701 atagtaatac atctttattg tctatattat taattaaatt tttaaaatct acaattactt
    14761 catcatagct tttatctaac ttcatatcga aagaaatagc actgcacttt ccaataatat
    14821 caccaactgc ttttaccata ctacttgctg tagtttctcc atgcatagca actataatat
    14881 taatgttatt cactatttta ttttgttcat cttgtttagc ttgtactatg aataatgtaa
    14941 tatatgctac agtttctata gataaaaata aatcaaattc attttcaatt attccaacta
    15001 tttttaatgc tgttttaaat tcacttctgt tatttcttct aatttgattc aaatctatgt
    15061 tgtttgtaga gctactttta tccaatacac tttttatata aattgccatt gacttaaata
    15121 ttgattcact tatatctatt tcttcatctt ctttaataat ttgtcttatt gattcacaca
    15181 tgcttttaaa cttaacatta ttaaatagag aagcatctgc tatattcatt tctacagatt
    15241 tattaagatt agtatttact gcattaataa tatttatatc attgtagtta ataacttctt
    15301 cttctcctaa tgacgtaaat acaaaatatt ctattccatg tgttataact tcatctgctt
    15361 taatagactt ctctctataa tcatcactca cttcatttat agatttatca aaatattttt
    15421 tctctatata aactggttct ttattatctc ttttatatct taggtatcca tttgcaacag
    15481 ctaattttat atcattttga agttgaccta cattattttt acaatcataa agtaatagtg
    15541 atttaattat ttctttatgt acttttattg aaatagaaat actttttgat tcttccttga
    15601 aaaaattttt gactaattcc attctttcaa tcattgtcct atctctcaat gatggtattt
    15661 ctattttcat tggtattctt ctattgaatg tatctaatag tgttgatgtc ggattttctg
    15721 tagtagcaca tattattaat accttagact ctctttcttt cgttgcatct cctagtcttt
    15781 taaatgttcc cttatctata aaagtaaaca acatttcttg accttctgct ggtagtctat
    15841 gaatttcatc taaaaatagt atccctccat ttgcaatttc caaaagacct tttctggaag
    15901 attctgcacc tgtataagct ccttgttcta ccccaaaaat atgtcccata agtaattgtg
    15961 cattattagc ataatcagca caattaaatg ttacaaaagg agctttattt tttctaattc
    16021 cactatctat agaataatcg tacatatatc tagcaatcat actctttcct actcctgttt
    16081 ctccatagat aatagtatga agtccatttg taggatagag cattgcgacc ttgcattttt
    16141 ctattatagg tcttaaacta tgttctttac ctattagtgt ttcaaaacta tcttttttta
    16201 ttttgttttc tacttttgtt ccttttttta tgccaagcaa ctcactttgt gtatcaagca
    16261 attcattctt gttaaggtta agatttgcag ggatataata cacaggtctt ccttttatct
    16321 tcgtaaccat accctcattg aataattggt ttaaatatgt acttatattg tttcttgcaa
    16381 ttcctgtctt ttctgataat tggttagctg taatcccttt ttcattttcc ctatatgatg
    16441 attctaaaac tttcattact ttatcttttt tatatatcat tacaagctcc cctacattat
    16501 agtattttat taactaaaac ccctatacac actttatttt ttaataaact cttattcttt
    16561 aactaaggtt ataatttatc aaactttcct tactttaaat tatagaaaat tattgtagaa
    16621 aaaataagat tattgctcat tttttctaca ttactatttt taattttata gtactttctt
    16681 aacaacatac tttacttgtt tttaatttta ttatatttga atttattata tttgaaaagt
    16741 agaaataaaa aaccctattt tggagtagtt ttaaaatttc tccaaaaata gggttttagt
    16801 ttgtatttca aataaatacc tgttcaagta tttttatact aaacaacttt taaattttgt
    16861 tggtatttat ttatgtctga tttagaagaa tatacaaaat gtccatctga aacctcaatc
    16921 caacttaata acttttcatt tgaacaatca tatccattag aattatactc tattctattt
    16981 cttgacttag catatctagg gtcaggaaca ggaattgcag aaagtagtga ttttgtatat
    17041 ggatgaatag gattattata caattcattt gaatctgcca attctactaa ttttccatta
    17101 tacataactc ctatacggtc actaatatgt ctcaccatag ataaatcatg agctataaat
    17161 aaacaagtta aattcttttc ttgttgcaac tttttaaata aatttactat ttgtgcttgt
    17221 atagacacat ccaaagaagc tataggctca tcagctatta taaattctgg gtctactgaa
    17281 agagctcgtg ctatgccaat acgctgtctt tgtccacctg aaaaatcaga tggatactta
    17341 tttgcataac ttctatcaag tcctactagc tttagcatct catatacttt attcattcta
    17401 tctgttttat ttttacagat accttgaatt tttagtggct ctgaaattat atctgcaatt
    17461 gtcatacgtg gatttaatga tgaagtagaa tcttgaaaaa taatctgcat acttttgttt
    17521 acatcttttt ttataaattt gtacgttttt ttatctgata tgcaatttcc tttgtaaatt
    17581 acttctccac cagtagattc atgtagtctt attatagttt taccagttgt agattttcct
    17641 gaacccgact ctcctaccaa tccaaatatc tcacccttat atatatcaaa acttatatca
    17701 tcaactgctt ttacagtagt acttttgtcc aaatgaaaat attgctttaa gttttttatt
    17761 tccagtattt tttctctatt cattagaaat cacccttcca caatttactc taactggtac
    17821 atctacttca ggtgcatctg ggtgcaataa ccaagttgct gcactatgtg tatcattaat
    17881 tttaaacatt ggtggctctt tttcataatc tatcttaagt gcatttttat tccttattgc
    17941 aaaagcatct ccttttggtg ggttcaataa atttggaggc attccaggta tattatataa
    18001 atagtcatcc tgcgaatcta aagtaggtaa tgaacccaac aacccccaag tatatggatg
    18061 tctagggtca taaaatatat cctctacagt tcctatttct acaatctttc ctgcatacat
    18121 aactgctatt ctatcagcta tagttgcaac tactcctaaa tcatgagtta taaatattat
    18181 tgacaaacct attttatgtt gtaaatcctt tattaaatca attatttgag cttgtatagt
    18241 tacatctaaa gcagttgtag gttcatcagc aatcaataca tctggattac aggcaagtgc
    18301 tatagctatt actatacgtt gtctcattcc acctgaaaaa tgatgtggaa attgtttaaa
    18361 tcttttctca ggattatcaa ttccaaccaa ttcaataagc tctatggctc tcttttttgc
    18421 ttcactttta cttatacctt gatgaatgat tacagcttct gcaatttgct ttcctattga
    18481 tatagttgga ttgagagatg tcatagggtc ttgaaatatc attgatatat tctttcctct
    18541 tatatcttcc atctcttttt cagacttctt aaccaaatca cttgatttaa gtaaaacctc
    18601 tccattttta atatatccat tgtatgggag tatcctcatc aaactcttac acagtacaga
    18661 tttcccacaa ccagattctc caactatagc caatgtctca ccttttttta gattaaaaga
    18721 tacatttctt acagcctgaa cttctccttc ttctacttta aaacttacag atagattatt
    18781 aacctccaat aaatgttcca aaaaccatca acccctatgc tattcaaacc ttagggatat
    18841 atttttatcc ctaaggtttc taattaattt cagtattatt caattgtcca gtcagctatg
    18901 ttccagaata tacctacacc atgatgacct aaaactgtat caggtgttaa tccttttatg
    18961 tttggttttc caacatatat tgcatctata taagcaataa atgtataagg catatcctta
    19021 gtcatttcta cttggaattg tttatataac tttaattttt catctttatc ttctgtttct
    19081 cttgcttttt gaagtatttt atctatagta ggattagagt aagcactgta atttgcacct
    19141 ttatctgttc caaatacttt atatgtatgg tcatctgggt caaatggact tccccaacct
    19201 attaaatgag catcttgatt agcccaatct gtttcagtta caacaacagc tttagcatca
    19261 acaccaattt cttttaactg ttgtgcacat attttagcca tatcaactct aacttggtca
    19321 ctctcacctg ctgttatctc gaaagctaac ttagtacctt ctttttcata gattccatca
    19381 gaacctaatt tccaacctag cttttcaatt tcttgtttag ctttttctgg attatattca
    19441 aacttttcta tatcaggatt attatatggt cccatttgta aaggtgaata tgctggtaca
    19501 ccatgtccta ataatacact gtcaactatt gcttttctat ctattgcata gcttaaagca
    19561 tttggtaatc ctttagcttt tttatcttta aagaatttag aattaaaatt gtataatata
    19621 cctctatagt cggctgtttt cattatattt actttaaaat tcttttcgtc tttttcaaag
    19681 ttagacatat ctttaggagt tatttgagct aggtctaatt ctcctgattt taattgcatt
    19741 gccttagcct tatcatctgg aacaatctta aagactactt tatctaatcc tggttctttt
    19801 acaaaataat cactattctt aacaagtgtt atactttgac ctttgtccca tttttcaagt
    19861 ttaaatggtc cagtacctat tggtttttga ttaaattcat cagtagctat atccttacct
    19921 tccaaagcat gttttggtaa tactcctact gttaaataat caagcattgc tgtatttgga
    19981 gcttttaaag taatttttat agtattatca ttaaccacat caatttttgt tatatcttca
    20041 taatttgatg ctatctcaga agcattatct ggattcatta tagtttctat tgtaaactta
    20101 acatcatttg ctgtaaattt ctctccatca tgccacttaa catcatctct taaattaaaa
    20161 gtatatgtat ttgttgcctc atcaaatttc cagtcctttg ctagacaagg aaccacctta
    20221 ttattttcat catgagctgt taatccatta aatattaacg aatttatttc tccatgttca
    20281 tatagtgcag gatttatact tgtatagtca ttacttccat aaacaagtac ctttccatct
    20341 ttaggcgtat ctgccttctt atctttgtct cctccactag aacaacctgc cattagacta
    20401 agtatcatta ctaaacttaa aacttttaac ttctttaatt tcatgatgct cccccttttg
    20461 ctttttataa aatatttttc aaagctttga ccccatttat ttaaatagat atttcaaata
    20521 cctcagtatt tgcttattta gtactcaaat gctgatttat aaattactag attttttatt
    20581 attattcttt cttatataat tacctatatt tgttatacac accaatgttg taaccaaaaa
    20641 tatacccgga atcagtataa tccaccatct atttgaaagt aatgcttcct ctgacaaaga
    20701 taacatactt ccccaagaaa caatttctat tggtaaacca attcctaaaa agctaagtgt
    20761 cgattcagta ccaatagctg cgcctatgtt tgttacaacc atgaacatta ttgatgccac
    20821 aaaatttgga agtaaatgtt gctttaatac atagaagaat cctcctccca tgctcttagc
    20881 tgctagtatg tattcgctat ttcttatttg tctaacttct gttctcacta tcttagatat
    20941 attcatccaa cttgttatcc ctattactat ggacatagat actggatttg aatttccaag
    21001 tatagcttgt acaaatatta taattaatat tgaaggtata ctaagtatga tttctgtaaa
    21061 cctcatcatt gcatcatcta cgagttcaga tgctgaacca cttatactac cataaacaat
    21121 tcctataaca gttgatatta cagtggaaaa tagtcctata aataaagata tttttcctcc
    21181 ataccatatc atagaatata tatctctacc cattgagtct gttccaaata aaaaagtttt
    21241 atttggagct aaattagaac ttgctaaatc catgtatgtt ggttcatgtg tcattataaa
    21301 agatgagaat acacttccaa tgactatgat tgataaaata ataattgata tatatggtaa
    21361 ttctttaatt tttttagata aggttttctt tgtttctata tgttcatctt ctgctactaa
    21421 aatataattt tctcctacaa tttcaaaatc actatattgt ggcttcatta gtatcacctc
    21481 tatcatattt cattctaggg tctattttat tgtttataat ttgagctaac atattcccaa
    21541 atactactaa agcccctgtt attaagcata aaactaataa catattataa tcatgatact
    21601 ttgcactttc aaaacaaagt gttcctaacc caggataaga aaaaactttt tcaactacat
    21661 aagttcctcc tagtatatga ggtatcgaaa tggccattat actaatatat gatggcatta
    21721 tatttctcag gcaatgctta aaaacaatag ttctattatt taaacctttt gctttacata
    21781 aaagcacata atcttctctt atttcctcta gtaatttatt tcttatcata tatgtgtaat
    21841 accatagatg gcttaatata agtactgtaa gaggtaagat tagatgtgat atcctactta
    21901 atatactgga ctcttctccc attgaataag caccactact tggaagtata cttaagttta
    21961 tactaaatat aagtatgagt actaaggcaa cccaaaatga tggaatacag ttggttattg
    22021 ttcctaattt gcatatgatt ctatcaatga gcttatcttc atgtaatgta caaaatattc
    22081 ctaacaataa ggctagcaca aaggtaagta tatatcctga accacctaat attatagtgt
    22141 ttatatagac atcatttata acagaagtaa cattttgttt atatttaaat gaaattccaa
    22201 attccccttt tgatgcattt gaaatccatt ttatatattg actgtatatt ggttcatcca
    22261 aaccaagttt tttcatagca ttttcttttt cttgtgtact cattctttct actccatccc
    22321 catagtaaga gattaatggg tctcctggag caagtcttgc catgtaaaaa acaataaaag
    22381 ataataaaaa cattactaaa ataaactgca acaacttttt caatatatcc tttaacaaac
    22441 cccaaccccc ctttgttgca ataaaaaaaa ccacataaaa gcaaacgtaa agtaacgtta
    22501 aaaccttcgt ggttccatta tcattaaaca aaattaaatt ttctatattt atctatgagt
    22561 taattttagc atcatttatt aactgtgtaa acaaactttt taaaaattgt taaaatttca
    22621 tcaaattatt ttatttatac ctaaaataaa atttttatat tctattcttc attattttct
    22681 ataaaattat aaaattttag gttgactata taagaaaagt atattatatt agtttgtatg
    22741 caaaccattt aagaggtgat tttattgaaa agtaattatg actgttttag aatagccatg
    22801 ctcttaaaag aactttattc taaaactatg tacacagtag aagaaaattt taaagaaaat
    22861 ggattaacac accaacagat tatagttata aaactgatag ctcataatca agaacttaca
    22921 atatcacaac tatgtgatga aatgtcttta gctaaaggta cggtttcagg cataatcagc
    22981 agattagaac agattggata tatagaaaaa ttcaagaaat ctaatgataa aagaaataca
    23041 tacgttaagt ttacaacaac aggatttgaa tttgccacaa attttaaaat taaaatgcaa
    23101 gaaagttttg atgatatttt taaaaattgt gatgaaaacg aattgagtga cttagtaaaa
    23161 aatcttagaa atatattggc aaaagtaaag gagagataat tatgaattat aaattaatac
    23221 ttgcaatagt atttataaca tcagctttaa ttttctacac tataggtgta tttggagaaa
    23281 gaaaggcaaa aattttaaaa aagaaacatg taattatatt ttggcttggt tttatatttg
    23341 atactttagg aacatttaca atgagtaaca tagccaacag ccatactttt gaagtaaaat
    23401 ctgctttatc acaaaacctt catagtatta caggtcttct tgcaattgta cttatgcttt
    23461 ttcatgcaag ttgggctact tttgtcctat acaaagatga tgaggaaaag aaaaaattct
    23521 ttcataagtt tagtatagtt gtatggacta tatggttagt tccatatttt ataggtatgt
    23581 ttattggtat ggctggatag taaaataaaa agtgtgtaag aaatactgta ggtaaatttg
    23641 tataagacaa atttatctac atccttcttt cacactttta catatttatt tataatactc
    23701 cattatttct ttcatgtttc ttaataccta tat
//
LOCUS       DAEOTL010000059        23604 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEOTL010000059 DAEOTL010000000
VERSION     DAEOTL010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.059"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            33..995
                     /locus_tag="KRH82_002677"
     CDS             33..995
                     /locus_tag="KRH82_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8655947.1"
                     /translation="MFPFRTQKLSKVNGITKDSVTNNRVYGADRHETNANVIKKFYTD
                     DELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVYKI
                     GGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKDYN
                     LNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNKQG
                     HGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVLRS
                     NDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            1237..3150
                     /locus_tag="KRH82_002678"
     CDS             1237..3150
                     /locus_tag="KRH82_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655948.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFGDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            3143..5362
                     /locus_tag="KRH82_002679"
     CDS             3143..5362
                     /locus_tag="KRH82_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBG8655949.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            5471..6301
                     /locus_tag="KRH82_002680"
     CDS             5471..6301
                     /locus_tag="KRH82_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBG8655950.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            6291..9758
                     /gene="addB"
                     /locus_tag="KRH82_002681"
     CDS             6291..9758
                     /gene="addB"
                     /locus_tag="KRH82_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBG8655951.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISTLEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINIIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEVYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            9758..13585
                     /gene="addA"
                     /locus_tag="KRH82_002682"
     CDS             9758..13585
                     /gene="addA"
                     /locus_tag="KRH82_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBG8655952.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKEDEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            13631..14842
                     /locus_tag="KRH82_002683"
     CDS             13631..14842
                     /locus_tag="KRH82_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBG8655953.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            14829..18356
                     /locus_tag="KRH82_002684"
     CDS             14829..18356
                     /locus_tag="KRH82_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8655954.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEVPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            18487..19740
                     /locus_tag="KRH82_002685"
     CDS             18487..19740
                     /locus_tag="KRH82_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBG8655955.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            19889..20941
                     /gene="ytvI"
                     /locus_tag="KRH82_002686"
     CDS             19889..20941
                     /gene="ytvI"
                     /locus_tag="KRH82_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBG8655956.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFHINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            21032..22258
                     /gene="pepT"
                     /locus_tag="KRH82_002687"
     CDS             21032..22258
                     /gene="pepT"
                     /locus_tag="KRH82_002687"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBG8655957.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCREKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            22465..23517
                     /locus_tag="KRH82_002688"
     CDS             22465..23517
                     /locus_tag="KRH82_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBG8655958.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISHSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVTEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
BASE COUNT        10057 a         2229 c         4229 g         7089 t
ORIGIN      
        1 attatgtggt tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa
       61 gcaaggtaaa tggaataact aaagatagtg ttactaataa tagagtatac ggagcagata
      121 gacacgaaac aaatgcaaac gtaataaaaa aattctatac agatgatgag ttagaggctg
      181 ttttagtagc taaatcagat gtacttgttg atgctttagc agcaggtcca ttggctgcga
      241 acttaaaatc tccaatactt ataacaccaa agacgtatgt atctgcatac cataaagata
      301 atttagaagc taaatcagct aataaggtat acaaaatagg aggaggattg acttctaagg
      361 taatgagctc tatagcatca tcattatcta aacacaatac gactccaaca gaaccaggaa
      421 atagtggggg caagacagtt atgattgacc cagggcatgg tggttcagca cctggaaatt
      481 catctggagg aatgattgaa aaagattaca atttaaatac ttcacttgca acaactgaat
      541 atttacgttc aaagggattc aatgtaataa tgacaagaga cacagataag actttatctc
      601 ttggaaatag aactgctcta tctaattcat tgaaaccaga tttatttaca agtatacatt
      661 ataatggctc aactaataaa caaggtcatg gtgtagaagt attttataag cttaaagata
      721 aaaatggagg gactactaaa actgtagcta ccaatatatt aaatagaatt ttagagaaat
      781 ttaaacttac aaatagaggt ataaaaacaa gagtacttcc tagtgattct acaaaagatt
      841 atttatacgt tttaagaagt aatgatatgc cagctgtact tgtagaatgt gcatttttgg
      901 ataatgaaaa tgatatgagt ttaataaact catctgcaaa agtaaaagaa atgggtacac
      961 aaataggtaa aggaatagaa gattcattaa aataaatgga aataaaaata tttaaaaact
     1021 taatgtaaat ttatagttgt aaatttatac taaagtcaaa aaatgaaata taagtgtatc
     1081 aatagtaaga ctgtatgtac atttgcacat gtgaatgcaa gtatatatac agtctttttt
     1141 tgtagttaaa tgcaataatt tgattgtgtt ttgtaaaata cacaatatga tataattaga
     1201 taatatacac ttaatttaat tgaggaaggt gattatatgg aatatttatt tgaaaaaagt
     1261 agtttaaaag aatatggaaa tgaagcttta gataaatata gagaattatt agataaaact
     1321 ggtaataatt caaggtgtat tcttttgtta gtaccaaaca ataacacaaa gatacgatat
     1381 gaaagggctc taagattaaa ttatagtgaa gaactgaaaa taacaacata tataagtttt
     1441 gtgaagaaag aattagttaa atactggcca ctaataatag aaaaatgtga tgaaataagt
     1501 acaaaggttg tatctccaac atttatatca aatagtttaa gtgaatattt aatagtgcaa
     1561 aaagttaagg aaaaaaggat acaagaagga tattttggag atattacagg aaccaataaa
     1621 tccatagcaa atagtataat gactaacata aataagtctg catttaattt aattgatttt
     1681 gattttattg gagaaaaaat atattcatca aagaaaaata aagatagtat atatagattt
     1741 tcatacactc aaatggatga aattatatca tattatataa attccttact atcaaattca
     1801 attttagata atgcattaag catatattta tacaatcaat acctacttaa tgatgatttt
     1861 tatttaaaaa acttatttac agaagtgaga tatataattg tggatagcct tgaaagctca
     1921 agtaatgcag aagttgattt tataacagaa gcattggata atacattaca aagttatata
     1981 tattttgatt atagtaggga ttattctgta tttaataatg tggatataga ctatataaat
     2041 gagaaaataa tatcaaaaat taagcctaaa gaagaaaata ttaaaaagaa ggagattaga
     2101 atagaagatt tatacttatt acctgcaaat atagaattaa atcaatcaag tcaattatat
     2161 aatgaaatgt tagatttaat aagtgaaaaa gttatatctc ttatagaaga agatgtatct
     2221 ccaagagata tagcaattat atctcctata aacaatagta tattggagca tcaaattaga
     2281 gattctttga tagaaaaaaa tatagatgtt tttagtacta agaaggataa aaaagctgtg
     2341 gattatccat atgggaatgc attggtagtg gctacatgta tattctatgg atatttagat
     2401 tttataaaag atgatgaata cttaagcttt ttagaaactc ttttagaaat aaataggata
     2461 aaagcattta agatttttaa tgaaacaaga catttaagta ttgataatat agatgaacat
     2521 agtcagtatc gtgatatttt acagtatatt gaagaaaaaa agaagagtga tataaaaata
     2581 catgaatttt taactcaatt ttacatagat aaaatgttaa atttaaaaga aggtaaaaag
     2641 aatgttgggt tatgtaaaaa gataatagct gaaagtgagt cttttagtga aagtttaagt
     2701 ctacttggga tgaaaaaaga aaagatattt atagaagctt taaaaagtac aataaacgat
     2761 tattactctg ttgtcgatat agaagagttg aaatccaaag acaaaatagt aataactact
     2821 ccttattcat atatatcatc aaatatagat agaagtatac aaatatgggt agatatagga
     2881 agtaatgctt ggaatatgaa aatagaaaaa gatataagta atttaattgt acttagaaaa
     2941 tcttttgaag aaaaaaagat ttatacaaat gaaatggaag aatattataa aaaatattat
     3001 ctatacaata cagtatataa tttgttatta aatgcaaaga aaatctatgc atttaaaagt
     3061 gaatatgcga ttaatggtta tatccaagag agtatattgt atagtatact tttaaaaatc
     3121 tcacataaag gagataaaaa ttatgattaa tataaattat agagaagacc agataccaat
     3181 aataaattac gataatggta ctatggcagt accagcagta ccaggtgctg gaaaaacatt
     3241 tataataaca aatttagtag ctaaactatt acttgaacag aaacataagg gtggtaaaat
     3301 attaattctt acatatatga atagtgctgt aaataatttt aaaggtagaa taagaaagat
     3361 tcttgaagag aataaaatag atgatactaa ttcgtatgaa gtaatgacta tacacagttt
     3421 ggctgtaaaa ataataaagg aaaagccaga agttgtaatg ttaagtgagg attttaatat
     3481 agctgatgat ttgcaaaaaa gtattatatt aaatgaatgt ataagtagat ttagatttga
     3541 aggtggagaa agagctttta gatggttttt aaaggagcaa aaagatgaac gctggaaaga
     3601 aataactctt gaagcctggg aaagaggttt ttttgaattt gcaggaaatg caataagtga
     3661 acttaagtat aagggaattt ctccagataa acttgaagaa atattgtcaa gaggacacaa
     3721 aggaatgctt aaaattattt taccaatata taaattgtat gatagaaaat taaagcaaaa
     3781 tggattgcta gattatgatg atatattaat tttagcagaa aaaactttaa gcttagacga
     3841 agggcttaga aagaagtttc aaactagata caaatatata tttgaagatg agtgtcagga
     3901 ctcaaatgaa attcaaggta atataataaa aattatatct agcgaaaata aaaacctagt
     3961 tagagttgga gatataaatc agagtataac aggaacattt tcatcatcag accctaaatt
     4021 ttttaaagaa tttataaata gtgcagattt ctgttatagg atggatatgt caaatcgaag
     4081 ttcaaaagat atacttgatt tagcaaacac tcttgtcaag tatgttacaa aggaatttag
     4141 acagaaagaa tgtagacatg ctcttgaaga tatgcaaata aaaactgtgc caaatggaat
     4201 gggatataaa gaaaatccta atccagaaca ttataatata aatgtaaagt ggtatgagag
     4261 ttggaaaatt gaaatagagc aaactgctag atacgttaag ggtataaaaa ataaatatcc
     4321 agataaaagt ataggtatat tggttccatt taatgaacaa gtgacacaag ttgctaaaga
     4381 acttagagag aataatctaa cctttgaaga attaggacca aattctttga ataaaaggaa
     4441 ggttataaac aatatagcat atattattga ttttatgtta cattgtgatg atgtagaaaa
     4501 gttaatagtt gtacttaata aagtttttat agatactgat aatgaagaag aaataaagta
     4561 ttttttagaa gaattaaaaa actattctac cgaagaaatt atttataatt ttgaatttag
     4621 taagttagat aatgatttaa tagaatttaa agaagaaagt gatatatact taagttttaa
     4681 aagaggaata gatattataa aacagatatt agaatatcca ataataaggt tagacctctt
     4741 agttttgttt attgggaaaa aacttaattt agaaaaagaa gataaagctg tactggatta
     4801 tatatctttt tatataaagt atctagtatc agaaaatata aatatggatt tagaagatgt
     4861 atataattta ttgtttgatg taaagaacag ggtgtttaat catataatag atgtggtata
     4921 tgagataaat ggatatgaac cagagcccgg tagtataaca ctatgtaact atcataaatc
     4981 aaaggggatg gaatgggatt gtgtgttttt actaggtctt gttgaatata atttccctga
     5041 caatattaat caaaagtttc agagtgataa atggtatcta aaagaaaaat ataaaaaccc
     5101 tatggcaatt attaaatcag aagttgaagc tatattaaaa ggaagtattt caacagatta
     5161 tgctcataaa acgaagattg attctataaa tgaaaagatt agacttttat atgtagggat
     5221 tactagagca aaggaaatgt tagtactttc aggaagtgct tatagagatg aaagtgatat
     5281 agggaataag agaaaagagc aaaaaccatg tatatattta agcagactta atcaacatat
     5341 tattgaaaaa aggtcaaatt aatatataat aagttattaa aagattgctt gaaatatatc
     5401 taaaagggga taaaacaata tgtacagtaa gtaactacta aaaaataaag ttaagagaga
     5461 agtgatatga gtgaacgata aattaaaata tttttcttat agtcaaaatt caattaacac
     5521 atataaatca tgtccattga aatttaaata taaatatatt gatagaataa attggaaaaa
     5581 tgatgatgtt ggtagtagag agtattatga aactttaaaa acaggaagag attttcattt
     5641 gatttgtgaa agatatttta gcaatatacc tcttggaatc tattttaatg aggatgataa
     5701 aaatagtaaa aagtttttaa agtggatgga aaatataaaa aaagttgttc ctattgaaaa
     5761 aggaaaaacg tatttgccag aatatgaagt aaggatgaca ttaaatgggg atataataca
     5821 ggcaaagtat gatttagttg taattggaaa taacaatata gaaatatggg attggaaaac
     5881 cgagtctaaa aagattgact ataaacacgt agaaaataga atacaaacta ttgtttatat
     5941 gtttttagca aaagaagtaa tacctaaagt tttaaaaatg gacataaatg ttaaagatat
     6001 aaatatgaga tattatcaac ctgaatttga tgacttacca attaccattt tatatgatga
     6061 agaaaaacat gaagcaaata gaaataaaat tcaaaattat ataagtatga taaaaaacac
     6121 taattatgaa gaacatacat acgaagacaa tctatacaat gatatagaaa aggtatataa
     6181 taaagaagaa cgtatgtgct atagaaataa aaagcattgc aagtattgtg aatttaataa
     6241 gttatgtaat ggcaaagaaa tagattatag tattttggag gcggaaattt atgggactta
     6301 ggtttgtatt aggtagaagt ggaagtggaa aatccaccta tatactagat gagattaaaa
     6361 aagaagctca aaaaaatgaa acgacatcaa ttatactttt agttccagaa cagtacacat
     6421 ttgaggctga aaatagagta agtaagctat tcttaggaaa agaaaaagat aagtatctaa
     6481 gagttagggt acttagcttt aagacactaa gtaatatagt tttttctcaa gtaggaggat
     6541 tgacagatgt aaatataaat tctagtggaa aagcaatgat ggtatataga gctattgaag
     6601 atgtaagtga agaattaaat gtgttttcaa aatcaaaatc gcagtctggt tttgtaagtt
     6661 caattacaga tatgatatca gaaatgaaac aatacaatat aagccctgaa atgttagaaa
     6721 atatatctgg agaattggat aatgaaactt taagtttaaa attaaaagat ataagtaaaa
     6781 tatataattc ttttgaaggg aaattgcatg aaaattatgt agatgctcaa gatatgttaa
     6841 cttcattggc aagtaaaatt gaattaagca gttatttaga tggagcttgt gtttatatag
     6901 atgaatttac aggttttaca ccaaatcagt acaatgtcat aaagagtata ttaaataagt
     6961 ctaaaagtgt taatatctct ttgactgtag atgatatcaa ctatattggg tacagtaaat
     7021 ctgatatgtt ttctagaacg aaatttactt attcaaaatt gactcaattg tgcaacgaag
     7081 aaggcataaa aatattgcca caagtaaatt taaacacagg tgttataaaa agatttgaaa
     7141 aagttaagga attacagcac ttagaaagat tttataatgc ttatccatat aaaatatatt
     7201 caaatccaac tgaaaatata aagataaaag agtttaacaa tttatattca gaggtggaag
     7261 agatagccag agaaattgta catttagtta gagataagaa tgtcagatat agagatataa
     7321 ccattgctac aagagattta aatagatatg attttttagt acactctata tttaatgaat
     7381 ataatatacc aaactttata gataagaaga gagaggcaaa aagtaatcca atagttattt
     7441 taattatttc aactttagaa atgaagaata gacgatatgg gtatgaaact atgtttaggt
     7501 atttaaaaag tggacttata ggaattgata atgatgatat aaatttacta gaaaattatg
     7561 tgttggctaa tgggattaaa ggtaaaaaat ggtttgatga aaaatgggat tatagaataa
     7621 ctcaaagtct ttcaggtcaa gaaagtgaat ttgaactgga attaaaagag aaaataaatg
     7681 aaataaaaaa tagagtatta gagcctatag taattttaca agaaaaatta agaggaaaaa
     7741 atagagtaaa agaaatctgt agatatatat atgaattttt attagatata aatatgccag
     7801 aaactataga aagtttaata gtaaatttta aggataaagg ggaacttgat gttgcaaatc
     7861 aatactcaca agtttgggac atagtagtgg acatattaga ccaaatggtg gaacttatgg
     7921 gtgatgaaat aatttcttta gaaaaattta taaaattaat aaccttaggt tttgatgaat
     7981 atgaattagg actggttcct cctagtatag accaggtact tgtaagtagt gtggatagaa
     8041 tgaaaaatcc agacacgaaa tatttatacc tagttggaac tactgatggt gtgtttccgc
     8101 tgattacaaa ggatagtgga atattgagtg ataatgatag ggaaagtctt ggaaacaaag
     8161 gaatcgaagt tgatattgat agtaagacta ggagttttga agaacagttt cttgtatata
     8221 aagctcttac ttcgacatct aagaatttaa ccataacata tccaatatca gaccatgaag
     8281 gtaaaacgct tagaccatca ataattatat caagacttaa gaagatattt ccaaatatag
     8341 aaaataaaag ttatttagtg gaagaaaata aaagcactga taaagatata cttaaaaaaa
     8401 taacggttaa atcccctaca tttaatgaac ttataaacat aataaaaaat tatgacagtg
     8461 atggttacaa tacagaagag attaatagta tttggttaga tatatatagg tactatttaa
     8521 aagatgaagt ctatagttct ataacaaaaa aagttataaa aggtcttagt tatactaatc
     8581 aagttcataa gattgaagag aaaaaaataa ggtcattgta taaaagtaat tctcttagca
     8641 tatctaggct tgaaaaatat gctgaatgtc catttgctta ttttatacaa tatggtctaa
     8701 aagcaaaaaa gcgtaaagag tattcattta caccaccaga tttaggaact tttattcata
     8761 atattttaga taggttttca aaagaacttt tacaagataa tttaacttgg agagatattg
     8821 atgaaaaata tatagaatta aagataggta taatagttga tgaaataatt ttaaagatac
     8881 caggatatat attaaatagt tctgagaggt ataaatacct tgcatataga ttaaagaata
     8941 tgttgacaac tgctataact ataattagtc agcaaataaa acaaggttca tttgaaccaa
     9001 tagattatga agttaaattt ggcaacaatg gaaaatatcc acctataaaa atggtgttag
     9061 aaaatggaca agaagtaagt ttaattggac aaatagatag agttgatgaa tttgaagaag
     9121 gagaaaataa atatataaga ataatagatt ataagtcagg caataagtcc ataagtctaa
     9181 cagaaatata ttatggtcta caattacaat tacttgtgta tttagatgca atccttgaaa
     9241 gtgcaaagga tgaagatata aatataaatc cagctgcaat actatattgt agaataaata
     9301 atccaatagc aaaatttaat gaagataaag atgatgaaga aatacaagaa gcaatattaa
     9361 aagaacttag aatgaagggg cttgtagtaa aagactctca catagttaaa gagatggata
     9421 aatcattaat agatggagaa aggaaaaact ctttagtaat accagtaggt cttactaagg
     9481 atggaaatgt aggtaaaagt acttcagcaa taagctatga ggatttcaaa ctgcttagaa
     9541 aatatgtaag gcatgctata aaggatttat gtgaagaaat gttaagtgga gaaatacgta
     9601 tagctccata taaacataaa gatggaacat catgtgactt ttgtgattac tctgctatat
     9661 gtcagtttga ttcaactata aaagataaca agtataaaaa tttaaataat aagagtaatg
     9721 aagagataat aaaaatgatg aaaggagatg ttaattagtg agttctccta aatggacaaa
     9781 agagcaatta gaagttatag aaagtagaga atgcaattta ttggttgctg ctgctgctgg
     9841 ttcaggaaaa acagccgtgc tagttgagcg tataattcaa atgataacaa gtagagaaaa
     9901 tccaattgat atagataagt tattagttgt tacatttact aatgctgctg cgtcagaaat
     9961 gagagagagg ataggggatg ctataggaaa agccttagat gaaaacccag aaaataaaca
    10021 tttacaaaac caacttgttt tattaaataa atctagtatt acaacaatac actcattctg
    10081 tttggatgtt ataaaatcaa actttcatag aataaactta gaccctaatt tcagaatagg
    10141 agaccaaact gaatgtgcta ttttgaaaca agaagcaata gaggaagtat ttgaagattt
    10201 atatgaagaa agagatgagg ggtttttaaa tttagttgaa agttatgcag aaagaggagg
    10261 agataaagaa gtacaagata ttatcttggg aatatattca tttgcaatgg cttctcctga
    10321 acctaaaaaa tggttgattg actcagcaga acgatttaat attgatgaaa attttgattt
    10381 ttcacagtct atttgggcta gagctatatt agacactgta aaaatagaga ttaatggtct
    10441 ttgtctaaat atggaaaggg cattaaaaga agtggaatca atagaagaat tagaaacttt
    10501 tgcagaaaag ttatctgttg aatataaaaa aattgctgac atttcacaag catgtaataa
    10561 atcttgggat gaggcatata aaaagatggc aagtatgtcc tttgaaaatt atgtaaaagg
    10621 agtaaaaaga atttcaaaag atgctccttc gtatataaaa gaatcaaaag aaaaggcaaa
    10681 aactataaga gataagacta agaagtcttt agaaagtata gtaagtgcta cattcaataa
    10741 agataatgat tctattagag aagaaataaa atatctttat aacatagtta aaccaatatc
    10801 tagtgttgta ctgagatttg aagaggaata tagcaataag aaaagagaaa aaggaataat
    10861 agattttaac gatatagagc attttgcatt aaatatactt acagatgtag atgaaaaagg
    10921 taatattgta ccttctgata tagcagttgg atatagaaac aagttttatg aaatatttat
    10981 agatgaatat caggatagta atctagtgca ggaagtactg cttaaagctg ttgcaaatac
    11041 agaaactcca aatagattta tggttggtga tgtaaaacag agtatatata gatttagaca
    11101 agcaaagcca gaattatttt tgcaaaaata taataactat aatgataaaa agggaagttc
    11161 ccatagaaaa ataatgcttt acaaaaattt tagaagtaga gaagaagttg tagatgctgt
    11221 aaattatata tttgaaaata taatgaatga gaatatagga gaaattgaat atacagaaaa
    11281 agaaagacta aatttaggtg caaattttaa tgtggataca gacgagaaat ctattattgg
    11341 tggagcaacg gagatacacc taatacaaaa agataataaa cttgatgatg atattataaa
    11401 tgataaagac gatagaatta ataacaaaga agatgaaata gaggaagaag aaaaattaga
    11461 taatatacaa cttgaggcta gaatggttgg aaacatcatc aaagatttaa tgaaagtcaa
    11521 tgaagatgga aaaattcaaa aggtctatga taagggaata gatggatata gacctgtgga
    11581 atttagagat atagttattc ttttaagagc tacatctgca tgggctccag tgtttgcaga
    11641 tgaattgatg aatatggata taccaacata tgctgatgtt ggagtggggt attttgatac
    11701 gattgaaata aaaacaatat tgtcattact tcaaataata gataatccaa tgcaagatat
    11761 acctcttata tctgtattaa aatcacctat atttggattt acaccagagg atttgattga
    11821 tattagagtt cagagtaaag ataaaatttt ttatgaggtt ttaaaaagta cagcagagta
    11881 tgatggattt acagattctc aaaatgaaaa tgagtctgag tttataccaa gtgaagagtg
    11941 cataaacaaa agtaaagatt ttttaattaa gctaaaggaa tttaaagaaa agtcaatgta
    12001 catgagtaca gatgaattta tatggtactt gtacacaagg actggatact atgcctatgt
    12061 tggagcattg ccaggtggaa gtcaaagaca agctaattta aaagtattgt ttgagagagc
    12121 aaaacaattt gaagaaacca gtcttaaagg aatattcaac tttgtaaatt ttatagagaa
    12181 attaaaaaaa tctagttctg atatgggaag tgcaaaaaca cttggtgaga atgcaaatgt
    12241 tgttagaata atgagtattc ataaaagtaa aggtctagaa tttccagtag tcatatgctc
    12301 tgcaatgggt aaaaatttca atactcaaga ttttaaaaag agtattttat atcatcataa
    12361 tttagggtat ggacctcaat ttgtagacta tgagagaagg atttcttttc caagtatagc
    12421 caaagaagca ttaaaaagca aaataaatat agaaaattta tcagaagaga tgagagtttt
    12481 atatgttgca tttacaagag ctaaagaaaa attgattata actggttcta ctagaaatat
    12541 acaagatagt ataaagagat ggtcaaatgg aattgaaagt ttagatacaa tatcacaata
    12601 cgagatatta aaaggtaaaa attttttaga ttggataatg ccttgtgtat taagacatag
    12661 ggatttatct aatctactag aagaagtagg attagacgca gtttttaatg ttgaacataa
    12721 ttcaaaatgg tatggaaagt tgtggaataa gaatgatatt ttagtggaaa agaagagtga
    12781 tgaagaaaaa gaaagtattg aagaaattct tgaaaaaata gatgtagata atcctgacag
    12841 tgattattac agtgaaatag aagaaaaatt aaactatata tatccatatg aatttagtac
    12901 aagaaaacct gctactatat ctgttacaga aataaaaaag atacaaaata attatgaaga
    12961 agagttaata aatactatat ttgaacaaaa agtaatatta aaaaagcctc tatttattca
    13021 aaatgaagaa gaaagagaaa aaataagtgg aacagaaaga ggtacaatag tccatttagt
    13081 tatggaggtt ttagacttaa aaaatgtaag tagtgtaaat gatataaaat cacaaataag
    13141 aggttttgtt tcaaaaggta taataacaga aaaacaagct agtatagtaa atccatataa
    13201 aatatataaa ttttttgcct ctaacatagg aaaaagaatg ttgaatgctg aaattataaa
    13261 tagagaaaaa tcaatttatg cacaagtaaa tatgaaagac atatatattt atgaaaagct
    13321 tataaacaat gacgataaaa aactttatga taatgaaagt gtcatgttaa gaggtatagt
    13381 tgatgcttat tttgaagaag ataatcaaat agttttggtg gattataaaa cagattttgt
    13441 aaatgaggaa aatataaatc aaataataga gaaatataaa aaacagttgg atttatatgc
    13501 agatattatt gaaactttaa ctggtaagtc agtaaaagag aaatgtatat atttatttgg
    13561 agttgatgaa gctgtttgtt attagttttt atatataaat taaacctaaa agatagagga
    13621 aggggaaaaa atgagattta ttcatacatc agattggcat ctagggaagt ccctagaagg
    13681 ccattctaga attgaggaac aagcaaagtt ttgtgaggaa tttataaaaa tagtagaatc
    13741 aaatgaaata gatatggtta taattgctgg agatgtatat gatacttcta atccaccagc
    13801 acaagcagaa aaactatttt atcagactgt atcaagactt gccaataatg gtcagaggtg
    13861 tgtattaata atttcaggaa atcatgataa tccagagaga ctctctgcaa taacacctct
    13921 agcacatgaa caggggatac ttatatatgg ttatccatta agtgctacga tagaagctaa
    13981 gtataaaggg tttgaaataa catatgcaac tcagggatgt acaaaactga atataaatgg
    14041 agaaaatatt gtggttgcta cattacctta tccaagtgaa aaaagattaa atgaagtttt
    14101 ttcaagtgaa gatgagtttg agaaacaaaa aaattattct gaaaaggtag gagatatatt
    14161 tagaagttta gaagaaaatt ttagaagtga tactataaat atagccgtat cacatatatt
    14221 tgtaataggt ggagagagta ctgaatcaga aagacctata caattaggtg gaagtttttt
    14281 agttgaaaga aaagatttgc cagaaaaggc tcaatatact gcactaggtc atttacataa
    14341 acaacaaaaa gcttccgaac gtttaaatgc gtactattct ggttctccac ttcaatatag
    14401 caaggatgaa agagcgtata ccaaaggggc atacatagtg gatataaaag ctggtgaaaa
    14461 accaataatt gaagatgtat attttaataa ttacaaacct atagaagtat ttaaatgtaa
    14521 tggaatagaa gaagcactag atatatgtga gcaaaatcaa gatagagaga tttggtcata
    14581 ttttgaaata aatactgatg agataatatc acagaatgaa attaaaaaaa tgaaggaact
    14641 attaaaagac ataatagaaa taaaaccaat aataacatct tgttatgaac aagaaagtgt
    14701 agatataaaa gaaaagtcta tggcagagtt gtttagagag ttctattctt ttagtaaagg
    14761 tgtagagcca aaaggagaac ttatggattt atttctagat ataataagtg aagaaggtga
    14821 atcagcagat gagaccaatt agattagaac ttacagggct taatagctat attgataaac
    14881 aagttataga ctttgaaaaa ttaattgaaa gaggtttgtt tgggatattt ggaactactg
    14941 gaagtggaaa atctacaata ttagatgcaa taactattgc tatgtatgga aatatatcca
    15001 gaaatacaaa agaatatata aacagtgtgt gcgataaggc aattatatca tatgagtttg
    15061 agataggaag caaaaacact agaagaagat acattgtaga tagaaccatt gctagaagca
    15121 aaacaggaac aaagacctct aatgctagat taatagaagt attgaatgac aatacccaaa
    15181 atgttttagc tgataaagtt gtggaagtaa atgaaaaagt agcacaggtt gtaggattaa
    15241 cggcaaatga ttttactagg tcagtagttt taccacaaga caaatttaat gagtttctaa
    15301 gattatcacg tgcagataga agagacatgt tagagagaat ttttaatctt gagaaatatg
    15361 gaagaagtct tggagaaaaa gtgaaaaaga gaaaaaatat acagttacaa aatttaaaag
    15421 atttgaaatc aaaattaagt caatatgatg gaattacaga ggaagtatat aacaatataa
    15481 accaagaatt aatagagtta aaaaatttgg aaaaagataa gaataatgct ttagacctag
    15541 ctcaaaaatc ttatgaagaa agtaaaacag tatatgaaga acaattaaag ttagaaaaaa
    15601 atgaacttag aaaaaatgag cttgatttaa aaaatagtga gataaaagaa aagattgctc
    15661 ttgtagaaaa tgatagtaac gctaaaaagg tagacccata cataagttca gttcaaaatc
    15721 tagaaaaaaa gatagatgaa gatagcttcg cagtaagtaa tttagaaaag aaattagcaa
    15781 tattaaatca ggagcttgaa gttacaaaaa atagatatga aaaaataaac aaaattaaga
    15841 atgaagaagt ccctaaattg agtgaagaaa aaataagatt gcaacaagca ataaaattag
    15901 aagaagagtt agttttatta gatagagagt taaaagagct aaaagaaagt ggaattaatt
    15961 taaataagac taaagttgaa ttagaaaaag taaagcaggt gtcagagtcc agaaaagatg
    16021 cagttactaa atctataaaa gaagttgaag gaaagattga taaagtaaat ataagtgcag
    16081 aattaaaaca aaaaatattt ctagcatatg aatacgagaa agattacaac aacgtattgg
    16141 aagaaaaaaa tcaaaagcta aataaactag aagaaatact caaagagaca gaaaatataa
    16201 atttaaaagt tagatatatt gataaagata agaatgatgt aaatcgtaat ttagaaaatt
    16261 tatcacttca cttggatgtt cttcttaaaa aatgtcctgg taagagtgct gatttacttt
    16321 taaaatctga atatgttact gaattaagaa ataaagcaaa taatactaaa gaaaatgaaa
    16381 ttaagaaaag cagtatacaa gatgaattaa agataatact tgaaagtaag tttaatactg
    16441 aaagggaagt aaatttacta aatgaaaaac ttgaaaataa tagaaagaac agagatgacc
    16501 tagaaaaaga attagaagaa ctaaagtatt taaatttagc ctctgaactt agacgtgaat
    16561 taaaagaaaa tatgccttgt ccagtttgtg ggtcaaaaca tcatgaaaat cataatataa
    16621 ctaaatatga tgaaaatata tcttttgtca aagaaaaact ggagaaatta gaaaaagaaa
    16681 aaataagtat aagaaacaat atagaggaat taaatgctaa agtaagtggg tatttatcta
    16741 tagaaaaaat gaagactaaa gaacttgaag atgtaaaagg aaaactaggg gggattccat
    16801 ctagtcaatt attaaaaaaa cttgatgaag aacaaagaaa acttgcattg ttaaaatcta
    16861 atattcagga gtgggagaaa gaaaaagaga gtactgaaaa taaagtaaca ttagcgaaag
    16921 aagaaaaaaa taaaattgaa aaagaagaat taaaaataag agagagtctg aataattata
    16981 agaaattaac aagagattta aacatagaaa tagaaggttt agaaaataaa tgtaaaaaac
    17041 ttaaacagga atacctagga ttaaagacga ttactaaagt ctctaatcta ttgtcaaaag
    17101 taaaagaaat aagggagaat gaaaaagaat tagaattact aagtactggg cattcaaatt
    17161 tattaaaaaa tagagactca ctagatatta aaataagaga aaatgagagt aaactacatg
    17221 aaatagagat agaattaata aaggctagag aattatatgt agaaaagaaa ttgagtaggg
    17281 ataataagta taaagaagtt attagcataa ctaaaggtga tttagctaaa aatcttttac
    17341 ataatgttga agaaaatata tgtaagatat tagaacaaga agaatcaagc aagaaaaaat
    17401 tggaagagca aagattagaa tatgaaaaaa acattgctga aaagcacaat atagatggta
    17461 gacttaaaac tgctaaggaa caatataaag accaaaaatc aacactaaat aaactattag
    17521 cagaaaataa atttgaaagt atatatgcag taaaaagagc tttattagat actgatgcag
    17581 taaaaaaatt gattgaagaa atactagagc atgaagaaga acaaaagtta ttatcattta
    17641 aaataaaatc atcaaaagaa aaattaaatg gaagaagcat aaagaaggag tactttgaac
    17701 aattaaaaga tgaaatttat aatttgaaag tagaaatagg aaatatatcc aaagatattg
    17761 gagctaatca aaatcagtta ataacattaa aagactcttt agataagata aatgatttta
    17821 ataaacaact taaggtagtt gaacacaatg tggacttatt ggaagaatta gataaatgtg
    17881 tacaaggaaa taaatttgta gaatatgttt ctacaaacca attaaaatat atagcgttgg
    17941 aagcatcaaa acgattggat ggaataacaa aaggaagata tgcacttgaa attgactcaa
    18001 cactaaactt tgtaatgaga gataacttta atggaggaga aagaagaagc attgatactc
    18061 tatctggtgg agagacattc ttgacatctc tatcattagc acttgctctt tcatctcaaa
    18121 tacaattaaa gggaagtgca ccattagaat ttttcttttt agatgaaggt tttggttcat
    18181 tagatagtga acttttagaa attgttatag aatccttgga aagattgcat agtaataatc
    18241 taagtgtggg tataataagt catgtcgagg aacttaaaaa tagagttcct gttaagctat
    18301 tagtttcatc tagtgaggct ggaataggtt caaaagtaaa aattgaatat agttagaaaa
    18361 tatatgttaa ttgaatatat tatctaatat ttccaaataa tatgtaattg tgatataata
    18421 aaaactaata ttaaagttat ttataattaa tattaatata aaaacatgta agtaggagtg
    18481 tggtaagtgt tggaatcgcc caataatttg attcagatta tttttttaat agtattactt
    18541 atagggtctg catttttctc agcatctgaa acggccttaa tgtcgttgag taaaatcaga
    18601 atcagatata tgcaagatga aggagttaaa ggagctaagt tagtaagttc attaatagaa
    18661 aatccaaata agcttttaag ttctatattg gttggaaata acgtcgtaaa tatagcagca
    18721 acatccatat caacatcttt gtttatagga ttaatgggag aaaaaggagt ggcacttgct
    18781 acagctgtta tgacagtatt agtattaata tttggtgaga ttactccaaa aacaatagca
    18841 gcaaataatt cagaaaaggt ttctctatta gtatctaaac ctataaaagc aattatattt
    18901 atattaagac caatagtatg gatatttaat ataattacaa atattatatt taaattattt
    18961 ggtataacaa ataaaggagc taaatcattc ataactgaag aagagctaaa aactatggta
    19021 aatgtaagtc atgaagaagg cgtccttgaa atggaagaga gagaaatcat aaataatgtt
    19081 tttgaatttg gagatatgca agctaaaaat gcaatggtac aaagaataga tatggtagct
    19141 atagatatgg aagatagtta tgatgagata atacaggtat ttaaaactga aaaattaagc
    19201 agaatgcctg tgtatgaaga aactatagat gatattgtag gaatacttaa tataaaagat
    19261 attatatttt tatctgatga agaaatagag tcatttgata ttaaaaatta tatgagagaa
    19321 ccttttttca cgtatgagtt caaaaagata acacaacttc ttgaagagat gaaacttgaa
    19381 aaaagtcaga tggctatagt tgtagatgag tatggtggaa catctggact tttaactata
    19441 gaagatttag tagaagtcat tgttggagat atagaggatg aatatgatga agaagaggat
    19501 gaaatacaag ttataaaaga agatgagtat attgtagatg gaagtactaa aattggtgat
    19561 gttaatgaac ttattggtgt aaacttggaa tctgaggagt ttgattccat aggaggtttt
    19621 ataattggac acctaagcag attgccagaa gaaaatgaag taattgaagt tgataatata
    19681 agattttgta tagaaagtat agaaaaaaat agaattaaaa aaataagaat atatacataa
    19741 tgtaataatg ttcttaaatt tattagaagt gtataaatat aaaagatatc ttttatattt
    19801 atacacttct ttttattttg tattcaaata aaactagtat gaaatggaca aaataaaaat
    19861 ataaattaga agaaaggaga tttttaagat gagcatacta gaaaataatt ttttatacaa
    19921 attaaaaaac aacactatct ttttttgtat atatacattg ttatttattt ttatttacaa
    19981 agcgtttcca tacatagctc cattttttct aggtgctata atagcactta tgattaatcc
    20041 tatatcacaa aagttagaaa ataagtttca tataaataaa ggtatctcta ctcttgttct
    20101 aagttttctt gcagtggcta tagtcagtac agttactaca ataatagtaa taaattcaat
    20161 gaaagaatta atgggatttt taaataatat atctgctaat cctgaggata taagtaatac
    20221 tattatgtat tttttaaata aaataaatga ctttatgaaa tcatttcaag aaatagccaa
    20281 ttttgatgta gaacaattag taaacaaatt cagtggtgaa gtaatgcaaa ttacaaaaaa
    20341 tcttcttact agtatacttg gattggctac ttctattcca tatattataa tatttataat
    20401 taccttgttt attgctacgt actttatagc aaaagacctt gataagattg aaaatagttt
    20461 ttataatatg tttactgttg atgttagaaa gaaagtaaaa aacgtaaaga aagaggcagg
    20521 gctttcactt gttggatata taagggccta tacaatactt atggctataa cattttttgc
    20581 aatctgggga agttttgctt tatttggatt gaaatacggt ctaatagtag ggtttgtagg
    20641 agctttaatg gatttaattc cattcctagg tataataaca atatatcttc cagtaattgt
    20701 ttattatttt cttataaaaa attattttat agctataagt atgactgtga tattttttgt
    20761 tttgtctttg attagagaaa tacttgaacc taaactagta tcagtaaatg ttggactaaa
    20821 tccattagct accctagcag cgatttttat tggaatccaa gtaaaaggaa taattggagt
    20881 aattttttgt ttgggtttgg tatgtatgca tgatatactt aagaaggtgg atatttttta
    20941 attataataa ttgatagatt tttttaaaaa taaaatttta ttcacaggta aataaaaaaa
    21001 tattaatctt attaagaaag agggtatata cgtgaaacaa aaagtagtgg aaagattttt
    21061 aaaatatgta tcatttgata caacatctaa ttctcagtgt gagaactgtc catcttcaga
    21121 aggtcaaaga gttttagcta agtatatagt tgaagagcta aaaacaatgg gtgttgatga
    21181 tgtgagttta gatgaaaata gttatataat ggctacttta aaaggaaata ctgatggtgt
    21241 ggatactata ggattcatat cacatttaga tacaattgaa gatgttagtg gaaaagatat
    21301 taaaccaaga ataatagaaa attatgatgg aaaagacata gttttaaatg aagcgttaaa
    21361 tgttattacg tatgtaaagg attctccaga gttggaagaa tttaaaggtg acgatttaat
    21421 agtcactgat ggaacaactc tacttggctc tgatgataaa gctggtatag ctgagatagt
    21481 gactgcaata gagtatctaa taaatcatcc agaaattaag catggagata taaaaatagg
    21541 atttacacca gatgaagaaa ttggtagagg tgctgattta tttgatgttg aaaaatttgg
    21601 agcaaaatat gcatatactt tagatggagg aatagttgga gaacttgaat gtgaaaattt
    21661 taatgctgca aatgcaacta ttactataca tggtagaaat gttcatccag gttcagctaa
    21721 aaataaaatg gtaaatgcta tacatatagc tgctgaaata tcagaaatgt tcccagcaga
    21781 tgaaagacca gaaacaacag aaggatatga aggattttgg catttaaatt ctataggtgg
    21841 aaatgtcgag aatgtaagta tggcttatat tattagagac cattgtagag aaaaatttga
    21901 aaatagaaaa tctattatga tagagaatat agaaaaaata aataagaaat acgataatag
    21961 agtggaattg gatttaaaag attcttatta caatatgaaa gaaaagattg agccagttat
    22021 gtttatagtt gatatagcta aagaagctat ggaggaatta ggtataaaac cacgtttagt
    22081 tcctgtaaga ggtggtactg atggagcaag attatctttt aatggattac cttgtccaaa
    22141 tatatttact ggtggattaa acttccatgg gaaaaatgag tgtataccag ttagttctat
    22201 ggagaaagct actaaactaa ttgtaagaat agctgaaaaa tatgctgaaa gagtttagtt
    22261 aaaaggtatt taaaaattaa gcatttaaag ttataatagc tatatcattc tttataagtc
    22321 aagctgatta taagcttgtg ttgtatttaa aatggtatag ctatttttgt aattattttt
    22381 ataaaagata attattttta gtttagggta tcaataaaaa gtatgaatat caataggtat
    22441 taacattcaa aagggggaat tgtattgaaa attaaatcta aaaaaataat agcatttgca
    22501 ctttcacttg ggattatgtt gccaagttgt gtatatgcag acactattag taaaaatcaa
    22561 aatgcacagg tagatatgaa caattatctt caaggtagaa aatctccaaa ggaggaaaaa
    22621 cttattggtg aagatagatt tgatacagcg ataaaaatat ctcatagtgg ttggaataat
    22681 ggttcagaaa gggtgtttct agttaactca aattcattgc cagatgcatt ggcttcaact
    22741 cctttggcaa gtaaattgga tgcgccaata ctgcttacaa ataaaaatag tataccatat
    22801 aatgtaacag aggaaataaa aaggcttaat ccagcagaag ttattttaat tggaagtgaa
    22861 ggagctattt catcaagtgt aaaagaatct cttgaagata tggaagtatt agtcagtaga
    22921 atcggtggag cagatagaga agaaacatct ttacttctta ctagacagct agatgatact
    22981 ggtgatttag gtgtctcaaa agtggcagtg gttaatgggt ataatggact ggcagatgca
    23041 acttcaatat caagcccagc tgcaagtgat aatacagcta taatatatac aggtaaggat
    23101 agcataagaa gtgaggcaaa gaattttatt acacaaaact caactaagac atacatagta
    23161 ggtggggagt acagtataag taaaaaactt gaaggacagt tagtaaactc agaaagacta
    23221 gcagggacag atagaaaaga tactaatgcg aaagttttag aaaagtttta tggaaaatca
    23281 agtaaggtta ataatatgta ttttgcaaaa gatggaagtg gtagagaagc tgatttagtt
    23341 gatgggcttg ctgctggagt attagcatca aaaacaaagt cacctgtagt acttgcaagt
    23401 ggaagtttaa gtagtgcaca gaaaagtttt ataaaaaaag taaaggctga taaatttgta
    23461 caagttggtg gaggtaaaaa tagtaaacca tatgcagaag cattagcctt acagtaatat
    23521 tgtgtaaatc aaaattaata tataataata gcaagtaaac caagttgcac ttcaatatat
    23581 ataataaaat aagtaaacta agtt
//
LOCUS       DAEOTL010000060        22919 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEOTL010000060 DAEOTL010000000
VERSION     DAEOTL010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.060"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            58..396
                     /locus_tag="KRH82_002689"
     CDS             58..396
                     /locus_tag="KRH82_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBG8655959.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(523..1812)
                     /locus_tag="KRH82_002690"
     CDS             complement(523..1812)
                     /locus_tag="KRH82_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBG8655960.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            1892..2596
                     /locus_tag="KRH82_002691"
     CDS             1892..2596
                     /locus_tag="KRH82_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HBG8655961.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHNKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            2688..3734
                     /gene="selD"
                     /locus_tag="KRH82_002692"
     CDS             2688..3734
                     /gene="selD"
                     /locus_tag="KRH82_002692"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2736..2738,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBG8655962.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            3752..5164
                     /locus_tag="KRH82_002693"
     CDS             3752..5164
                     /locus_tag="KRH82_002693"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBG8655963.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            5278..7161
                     /gene="selB"
                     /locus_tag="KRH82_002694"
     CDS             5278..7161
                     /gene="selB"
                     /locus_tag="KRH82_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBG8655964.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            7266..10004
                     /locus_tag="KRH82_002695"
     CDS             7266..10004
                     /locus_tag="KRH82_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBG8655965.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIVSGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(10123..11067)
                     /gene="manA"
                     /locus_tag="KRH82_002696"
     CDS             complement(10123..11067)
                     /gene="manA"
                     /locus_tag="KRH82_002696"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBG8655966.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFSFEGNLEIICSHI"
     gene            11240..12601
                     /locus_tag="KRH82_002697"
     CDS             11240..12601
                     /locus_tag="KRH82_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8655967.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            12689..14578
                     /locus_tag="KRH82_002698"
     CDS             12689..14578
                     /locus_tag="KRH82_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8655968.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            14593..15048
                     /locus_tag="KRH82_002699"
     CDS             14593..15048
                     /locus_tag="KRH82_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8655969.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNSINEALGL"
     gene            15107..15424
                     /locus_tag="KRH82_002700"
     CDS             15107..15424
                     /locus_tag="KRH82_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBG8655970.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            15449..16711
                     /locus_tag="KRH82_002701"
     CDS             15449..16711
                     /locus_tag="KRH82_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBG8655971.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            16816..17880
                     /locus_tag="KRH82_002702"
     CDS             16816..17880
                     /locus_tag="KRH82_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBG8655972.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKALGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            17934..19112
                     /locus_tag="KRH82_002703"
     CDS             17934..19112
                     /locus_tag="KRH82_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBG8655973.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(19303..20361)
                     /locus_tag="KRH82_002704"
     CDS             complement(19303..20361)
                     /locus_tag="KRH82_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBG8655974.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLEDGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKDGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            20428..20799
                     /locus_tag="KRH82_002705"
     CDS             20428..20799
                     /locus_tag="KRH82_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBG8655975.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            20836..21510
                     /locus_tag="KRH82_002706"
     CDS             20836..21510
                     /locus_tag="KRH82_002706"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBG8655976.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            21759..22598
                     /locus_tag="KRH82_002707"
     CDS             21759..22598
                     /locus_tag="KRH82_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBG8655977.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
BASE COUNT         9154 a         2440 c         3948 g         7377 t
ORIGIN      
        1 ttatatataa tataaataat aatgaaaatc aatatcaaat aaatgggagg aaatctaatg
       61 aacttattag tgattggtgg tcatgaaaga atggaaaaag attatatggt tatggccaag
      121 aaaaaaggtt ataagacaaa ggtatatact accatgtcat ctaaattaaa taattctata
      181 ggaagaccag atgcagttgt catacttaca tcaactgttt cacataagat gtctagaacg
      241 gttgagtctc aagctaaaaa acaagatata ttaatcgtaa ggcataaaaa tagtagtaag
      301 gtagcattta atgaatgtct agatatggtt gatgaatgtc tgggaaattg ttcaaaatgt
      361 aagcttaaag acaaacaaaa acaaaaaaat atataggtat aaaaaataca taaacataaa
      421 attaaaagta ctgagataat agttataatt attatctcag tacttttaga tttataagga
      481 taagtatatt ataaattttt tattataatt tctaactact tgttactttt tcatattttt
      541 tttacttcta gctttttttc tttttttctt ctttatattt gaagctatta taaataaaac
      601 taaaagcact agaatacctg caataatctt aacaaaagtc attaaaacat tattttcagt
      661 caaaaatgga agactgctat caagattatt ttttgcaatt aagtctatac tgttttctag
      721 tttaccatta ttatatacat ttaaagtacc aaccttagct ccttttttta taggcaaatc
      781 aattttattt aactctgttt tggtatcata attgccttga gattcatctt tttctaagaa
      841 tatcctataa ctattttttg gttcataaat caattcatgt tgttttgtaa acaatacttt
      901 tttagtatct gtgtattttt ctttatcaac aatagtagca cacttaaagt tatcaaatcc
      961 ataatcaatc agaatacgtg agtctaaata taaatcagca ttagttgaat taaatacagc
     1021 aacgataact cttctgccat cttttacagc actcgataaa agacatttac cagcagcatc
     1081 agtatatcca gtttttatac catcaactat atcatatttt atatttatag gttgaccttt
     1141 gtatgtaatc ttatcatgtg atgtcaaaaa cttattagtg tttacaaagt atctctcata
     1201 aggatatgct tttgtagctt caaatttaag tgacttagtt tttacaattt gtctaaaagt
     1261 atcattattc atagcttctc tagctatgag agccatatca tgagctgttg tgtagtgatt
     1321 tgggtctggt aatccatgag gattattaaa atgagtatta gtagctccaa ttttttttgc
     1381 ctcagagttc attaggtcaa taaatttttg tacattgcca ccaccaacat atctagctaa
     1441 tacaaaagca gcatcattag cagaatgaac caaaagagca tctagtaact gctttacagt
     1501 aaaagattcc ccatttttta gatacatact agagccatct atttgaggta aatctttaat
     1561 ttctattact tgatttaaat ctttaacctc ctttagaact aaacaagctg tccatacttt
     1621 agttgttgaa gctggataaa gcttagaatt tccatcctta ttatatagta ttttgccaga
     1681 ctcatagtcc attaaaactg catgtttagc aactatagct ggttcattat ctgcaaaaga
     1741 gatattagag cttcctaaaa atgaagtaaa tatcaataaa cagattaata aaagtgataa
     1801 atttcttttc attgtgagcc tccaaatttt aaattcatct tttagtatag catatatttg
     1861 tcaataatta aaagaaagga gtgattaata tatgaaaaaa aaggtaaaat ttatttcgtt
     1921 ttttgtttta tttattttaa taatatcatc aataatcgtt tataaatcgc ttattttcaa
     1981 agatgatatt tatgttgtaa gtaaaaaaaa tttacctaat gaaaaaacac atgttgtaga
     2041 gaatgaaatt aaaggtgaag ataataatca caataaagta actaaagaca tagataaaaa
     2101 ttttcaaaat aataaaataa ctatatacat aagtggagca gtaaatagac ctggaattgt
     2161 aactatagag tcagacaaga gactttatga tgctgtagaa ttactaggag gaacgacaaa
     2221 agaagcagat ttaaatggag tcaatctatc agtaagatta gaagatgaac aacattacat
     2281 aatacctaaa ataggtgaag caacatctgt tacaagtaat gatgattcca ataaaccaaa
     2341 tcagaagaat gagtcaagag gtgagcctaa aaataaatcc aataaaaata tatctaacga
     2401 atcaaaagta aatataaatg tagcgactat agaagagttg gattctctac ctggggttgg
     2461 agaagctaca gccaataaaa ttttacaaca cagagaagaa aatggacagt ttagttcaat
     2521 tgaggaaata aaaaatgtaa atggtattgg agataaaaag tatgaaaata taaaagattt
     2581 aatttgtgta gactaaaata taatacaaaa cttacatata gatatgttat tataaatatg
     2641 tatgtatatg tgtgtacatg tggaaattta gtaaaggagg cacttttatg aaaaaagaac
     2701 aaaaaaaact tacagagatg acaacagcag gtggttgagc cgctaaaata gggccagagg
     2761 ttctggcatc agttttatct caattgccta aaaatgataa tatagaaaat ttattagtag
     2821 gactagatac agcagatgat gctgcagttt ataaattaaa tgatgatatg gcacttatcc
     2881 aaactttaga cttctttaca ccaatggtag atgacccata cgtatttggt caaattgctg
     2941 catcaaattc actatcagat gtatatgcta tgggaggcaa acctttggtt gctatgaata
     3001 ttgtttgttt tccatcatgc catgatatgg atgtacttgc agaaatatta aaaggtgggt
     3061 ttgataaagt gaaagaaagt ggagcacttt tggttggagg gcatactgta gatgacaaag
     3121 agcctaaata tggtctttca gtttctggga ttgtaagtcc aaataaagtt ttatcaaatg
     3181 ctactgcaaa acctggtgat aagttaatta taacaaaacc aattggagtg ggtgtattaa
     3241 atacagccat gaaagaaggt atggtagaac aacatatagc agataaagta atagaaataa
     3301 tgatacattt aaataaatat gcagcaatga gttttgagaa atttgatgta aattcggtta
     3361 cagatataac tggttttggt ctacttggtc atactttaga aatggccaaa gcttctgaag
     3421 taagtattga aattgaatca aaacatgtac caattattga aggtgcaata gaaatggcac
     3481 aaatgggaat tatacctgct ggtatgtata aaaatatgca ttatgtatct aaagatgtag
     3541 aagttgtagg aaatatagaa gttgcagttc aagatatttt atacgaccca caaacatcag
     3601 gagggttgtt aatttcagta aaagaagaac ttgcagagga acttgtaaaa gatatgaaat
     3661 taaatggagc aatagaagct aaaattatag gttctgtagt tccaaaaggg gaaaaatata
     3721 ttacagtttt ataaaatatt atagagaaag agtgattgtt ttgagcaaaa gagaattgtt
     3781 tgcaatgttg ccttcagttg atgaagtatt aagtgataat agaattgtag aaataataaa
     3841 tgaatatcct agaagtttag ttttagaatc tgtgagagaa gtaatagatt taaaaagaca
     3901 atttatatta agattaaaag aagatgcatc aaactctgta acaatagagt ttggtgaaat
     3961 aatagaatct gcaatagaga gagttaagtt aaattactca ttatctttaa aaaaagttat
     4021 aaatgcaact ggtacagtta ttcatacaaa tttaggaagg tctttactta gtgaagatat
     4081 aaaagatgaa ttatggtgtg ctgcttcaag gtattcaaac ttagaatacg atttggataa
     4141 tggagaaaga ggttcaagat actctcattt aactagtaca ataaaaagac ttactggagc
     4201 agaagatgta ctagttgtaa ataataatgc agcggcagta cttcttgtac ttagcacaat
     4261 ggctaaagga ggagaagcaa ttgtatctcg tggagaatta gttgaagtag gtggttcatt
     4321 taggattcca agtataatgg ctcttagtgg tgcagaatta gttgaagttg gttcaactaa
     4381 taaaactcat ttgaaagatt acaaggaggc cattacagaa gatacaaatg tattgatgaa
     4441 ggttcataca agtaattata gaataatggg attcacagag agtgtttcta tagaagaatt
     4501 ggttaattta ggtaaaaaat ataaactacc tgtaatagaa gacttaggaa gtggagtttt
     4561 tatagattta tcaaaatatg gtttatctta tgaaccaact gtattggatt ctattcgaca
     4621 aggtgcagat gtagtaactt ttagtggaga taagatgctt ggaggtccac aagcaggtat
     4681 tatagttggg aaaaaagagt atatagaaaa aatgaagaaa aatcaactta ctagagcact
     4741 tagagttgat aagcttacaa tatgtgctct tgaagcaaca ttgagaatgt atttagatga
     4801 gacaaaagct atagaaaata tacctacttt aaaaatgttg acatataaaa ttgaagaatt
     4861 agaagtaaaa gcaaataaac tatttgaaaa aataactgct ttaaacttaa atgcaaacat
     4921 aaatatagaa gatggatttt cacaggtggg aggagggtct atgcctcttg aaactataag
     4981 tacaaaggta atatcaataa ctcctgaaca tatgaatgtt tcatctttag aaaaaaaact
     5041 aagacttagt gaagcacata taatagccag agtgtatgat aataaatatg tactagatgt
     5101 aagaactata tttgatgatg aatttgatgt aatagttgag gaattgagaa aagcatttaa
     5161 ttaaataaat ttgagttaat aaatattaaa tttagaagta taagtatgaa gttttaatta
     5221 aaaaatagct acacacactt gtgactttag tcatagcagg tttagagggg gcaaaaaatg
     5281 aaaaatgtag taattggaac agcaggtcat attgaccacg gaaaaactac tcttataaaa
     5341 gcattgactg gaagagagac tgatacatta gatgaagaaa aaaagagagg tatttcaata
     5401 aacttaggat ttacttattt tgatttacca aacaatagaa gagctggaat tgttgatgtc
     5461 ccaggacacg aaaaatttat aaaaaacatg ttagctggag catcaggaat tgatatagtt
     5521 ttacttgttg tagcagcaga tgaaggagtt atgccacaga cagttgagca tttagatatt
     5581 ctaagctttt taaatatcaa aaatggaata gtggttctaa ctaagtctga tactgtagat
     5641 gatgaattta gagagctagt aaaagaagat atttgtgaaa aaataaaagg aacttttctt
     5701 gaagatgctg aaataattga agttgattct atatctaaaa gaggtataga cactcttatt
     5761 gaaaaaatag ataaaatgag tgatgatata gaagataaaa atgaaaattc tccagcaaga
     5821 cttaatatag acagagtatt ttcaataaaa gggtttggta ctgtaataac aggcacttta
     5881 atagaaggaa agataagtat agaagatgat ttggttatat atccacaggt attaaaaaca
     5941 aaaataagaa gtatacaagt tcatggagaa aataaagata cagcttatgc aggtcaaaga
     6001 acagcaatca atatatcaaa tgtaaaagtg gatgatataa aaagaggaga tgttttagct
     6061 gcaccaaact cattggagga atcaatgatg ttagatgtaa aattatcatt ggtaaatcat
     6121 ttagataaag gattaaagca ctgggataga ttaagattgt atcatggaac tagagagata
     6181 ctttgtagag cagttccact agataaggaa ttaattgaaa gtggagaaag tggctatgtt
     6241 cagttgagac ttgaagaaag catagtatct aagaaaggtg atacgtttgt agtgagacgt
     6301 tattctccaa tggaaactat aggtggaggt gtaataattg acccatctcc taaaaaacat
     6361 aagaaatttg atgaaaaagt tatagaagca ttaaaaataa aagaaaaagg cgaactaaaa
     6421 gatataatag aagagtactt aaaaaggaat ttaaaaaatt atccaaatat aaaagaaata
     6481 atgagctata gtggtgctca tgaagaagat gtaaaaagag cgcttgaaac acttatatca
     6541 gaagataaag tatttattat aggaaatatg tatatgcata taaatcaata caataaatta
     6601 aaagaaaata caataaagct tttaagtgag taccataaga agtataggct tagaaaaggg
     6661 atactaaaag aagaagtaag gtctaagata gagagtaatt ttaagactag ggagatggat
     6721 attttattag aaaaattgtc tacagaaaat gctataaaaa tagaaaataa tatagtatct
     6781 ctattagatt ttgaggttat tttaaatgat aagcaaaaag aaatagcaaa aaaaatagaa
     6841 aaaagattaa aatcatgtgg agtttcttct atactgacaa tagatgaagt ttctgaagga
     6901 aatcataact atgctgaagt attggagtca atgataggta ataaagtaga gaaattagat
     6961 gatttgtata taatggacaa agatatttat gaaaatgcaa agaacatttt gataaattat
     7021 ataaaagaaa ataaagaaat aacattagga gaatacagag atttgattga ttctagcaga
     7081 aagaattgca tgattatatt ggaaaacttc gatagaaaca aaataactaa aagagtagaa
     7141 aacaaaagaa ttttgtttta gcagaaaatg tctgtttttg ctttaaggta taaagaagga
     7201 attataatgt cgagtatcgt ataattaatt agtataaaat attaattaag aggaagtgta
     7261 aagtattgaa gaatataata cctgatgtaa aaccagatat aaaagaaaga gaagacatga
     7321 gccttttatt tataataatg ggctcagtac ttttattatt tattataaaa gatatagaga
     7381 aatatgaaac tttattacat gccatatata cgatattttt agtagctaca ggagtaatta
     7441 tatttaatac tacaaaattt aaagtagatt cattttctac atttttagga ttaattttta
     7501 tagctactgg agtattggag tgtatatatt tatttaattc cttggggatt aaaactaagt
     7561 ctataatgga gattaacatc acaatatcag caataacaga tttatttcct atactgggtg
     7621 tatacttaag ttttaaattt gttaaggata acaaacaaat ttattcaagt gtaattttat
     7681 ttatagcaac tgctacatta acaataacat ctttattcat aatatcagga atttgtgact
     7741 atctgggaaa tggtaaatca caatatgctt taggagttat aatatctata ttcataataa
     7801 ttatttctat tgttagtgga attgaattaa attcaagttc aaataaaggc aaatgggaat
     7861 atgatgaaaa aaagattttt aacagaataa tagtaataat aatcttatca agagttccaa
     7921 atctattgca tatagttatt gataatagaa atgtagagag gatattatcc cagataataa
     7981 taaatgtagc cttatattat ttatataatt acatagtatc taagaatatt aagaaaacag
     8041 cactggaatt gcatgatacg aatgaagaat taacaaaaaa aacggaaagt ttaaaagaaa
     8101 agaataaaaa attaatctat gagacagaaa agatagagga acttaaggga atacttatga
     8161 aaagagaatc taggctacaa tctacattag atgtagcagt aaatagcata gtagtattta
     8221 gcaaagatgg agaaattaca tatgcaaata agagctttag aaatactttt ggagactata
     8281 aagaacaaga taaattgact gataaaataa aaaacttcaa tgatttgata gaaagcattc
     8341 attatgtgtt tgttcatgag aagaatgcag agaaacttat tagtacaagc gataataaag
     8401 tttatcaagc tatatttgca cctttaatta ttgcttcaca aacagaagga gtattgtgtg
     8461 tactagaaga taagactaag aaaaaggagt acgaacgcaa acttattgaa gcaaataaga
     8521 gaagtaaaga ttttttagaa agtattggag atggcatagt agtgcttgaa ggtaataaca
     8581 aaatatatgt taataatgca tgtagggaaa tttttaaaaa taatttagag agtattgatt
     8641 tttcattagt atgtaaaagt gaagaaagta tagaaaaaag atatgtaata gatggtgaag
     8701 taaagtatgt agagatgagt ttttctcagt atactaatgc tggtactaat aaaactatta
     8761 ttgtaatacg tgatacaacc tctcgaaaaa tatctcaaat aaaacttgag gaaagtcaat
     8821 catcatattc aagatttata gatatattac ctgatggcat atgcttatta aaagaagatt
     8881 taagtataaa ctatgcaaat aagtcgtttt tagatatgct agcttttaca aacatagatg
     8941 atataaaaga ttctaatatt aaactattaa tgaatgcgaa tactgaagaa aaaatgaaat
     9001 ttacggataa tatggctaaa gttttaaatg aaaatagaag tatactttta ctggaatatg
     9061 aattgataaa tagttatgat gatatagtag aagtagaatt aagtgcatta ccttttgcta
     9121 tatacaatac tagatacata atgcttatta taaaagattt agtacataag aaatattccg
     9181 agcaagcaga aaaagaactg cttgaaagat ttaaaacaga taaaatcaaa acggagtttt
     9241 ttgcaaatat gtctcatgaa ttaaaaactc cactaaatgt tatatctagt tcaaatcaac
     9301 tggtagattc tttctataga aatgaaaaga taaaagatta caataacaat attaaatctc
     9361 atgtggattt agttagacaa agttcttata ggcttcaaag attaataaat aacattatag
     9421 atttaacaaa gatggagtct gggttctata cactaaaact tgcgaaatac aatattgtat
     9481 ctgtaataga agacttattt atgaatatag aagagtatgc acttagaaaa gacataaaaa
     9541 ttctttttga tacagacctt gaagaaatta atgtttatat agacaaggtt gaaattgaga
     9601 gaattatgtt gaatctattg tcaaactgta ttaagtttac tgataatgga ggctggatat
     9661 atgtaagtat tcattataaa atagataaag taatcataag tgtaaaagac actggagttg
     9721 gaataccaca agataaatta gaattgattt ttgaagaatt ttcacaagtt gataagactt
     9781 tatccagaaa tactgaagga agtggaatag ggcttgctat agttaagaat ctagtaagtc
     9841 ttcatggtgg agatatagaa gtagtaagtg aagtgaataa aggcacagag ttcttaattt
     9901 cacttccaat gaagggattt agtagtgaac attacacaga agataagaga atatataata
     9961 ttcaagaaaa aataaaaata gaattttctg atatatacta ttaaaaatga ttatgagcaa
    10021 aaataaaata aaaatactat ttgtttaaat atttaagttg taagaaatag gctatcataa
    10081 ggtaaattat tatgatagcc tatttttagc taggttttat atctatatgt gagaacatat
    10141 aatctctaaa ttaccttcaa aactaaaatc tccaaagtcg tttggtagta taaaatgcat
    10201 accctttttt aaattatatt ctacagaatt gtgtataagt tttccatttc catccaacac
    10261 actgtataaa gaaaaaggtg tattgtgtgt aaaattacat tttccaaaaa catctaattt
    10321 ataaacacta aaaaattcgt ttgacacaaa tgttgtgcat ttaaagtctg atgttgatac
    10381 gattttatag tcagtatcga aatttatatg aggaacattc gtaacatcta ttgatttttg
    10441 aacatgaagt tcacgcttat tacctgaatt gtcagttcta tcataatcat agactctata
    10501 agtagtatct gagttttgtt gagtttctaa aatcaatgtt cctttgcata tagcatgtat
    10561 agtaccactt ggaacataga aaaagtctcc cttttttatg ttaacctttc taagtagttt
    10621 gtcccattca ttattattta ccatatttac aaattcttta tgagattttg cattatgacc
    10681 tattataatt tctgcatcat cagaacaatc tattacatac caacactctg tcttacctaa
    10741 ctctccattt tcattttttt tagcatattc atcatttgga tgaacttgaa ctgataaatt
    10801 atcatttgca tccaatattt ttgtaagtaa aggaaactta tcaccaggtg tgtttccaaa
    10861 taattctcta tttttattcc acaattcaga tagtttttta cctttatatt ttccattttc
    10921 tattaagcaa tctccatttt tatgagagct tatagcccaa cattcaccag ttgttggcga
    10981 atctatttca taattaaatt tatctttaag tgcagtacca ccccatattc tatccataaa
    11041 aataggtttt aaaaataatg gttccataat tctgttcctc ctatgatatt aaatttatcc
    11101 tacaaataat tatatataaa tagattataa aatcaatagt aaaaaagttt tgtcccttga
    11161 aatgacataa agtataagga gttattaaat aagataaact atgatatata atataaagtt
    11221 ctaaattgga gtgataatta tggagttgtt taaggcagaa agcaaaaaat atgaaaaaga
    11281 atttttaaaa ttattggagc aatgggttag tataccttca ttttatgata gaaaaactgt
    11341 atctaaagat atgccttttg gaaaaggagt atatgatgca ttaaactggt ttgaaaatct
    11401 aggtagagaa aacaatttca aagtaaaaaa tatagataat catgctgttc aaattgaata
    11461 tggaaatggt aaagagtatg tagatatatt tggacattgt gatgttgtaa atccaggtga
    11521 aggatgggat agtgaaccat ttaaactaaa tattataggt gataaattag ttgctagagg
    11581 tgtatctgat aataaagggc ctatgatagt gaatttttta gcactaaaaa tgataaagga
    11641 tttagatatt aatttaaaaa gaaaggttag attaatagct gggggaaatg aagagagtgg
    11701 atttaaatgt ataaagcatt attatagcaa agagccatat ggtgtatgtg gatttactcc
    11761 agatgctaaa tttcctgtat taaatggaga aaaaggtgga gcaataataa agttaatttc
    11821 aaatatagac gataaatctt tatatataag tggtggaata gagtttaata caataccaga
    11881 taaagtttat ataaagaatg tagaaaaatt gggtaaagat aatatatgtt ttgatattaa
    11941 caatatatcg ataaattatg ataatggcaa ttatattgtg tatggaaaag gtggtcattc
    12001 atctaaaccc gaaaaatcaa taaatcctat attagctaca attaaacttt tgtcagaaaa
    12061 tattgatgaa aaatggacaa aagatttata taagttgata aatcaagata atataaatgg
    12121 aaacttattt ggtttaaata ttgaggggaa atgtgggatt ttatcaatgg tgccaacaat
    12181 aataaatata gtagatggaa aattagaagt agttttaagc gttagatatc cagaaatatt
    12241 aaccattgaa gatataataa aaaaatttaa tttgtatatg gagcaaaata atattaataa
    12301 atttgagctt attggggaaa atttaaagca agcaaattat atagatagaa attcaaaact
    12361 tgtaagaagt ttgcatgata tatatataaa gtattctgga gatttaaaaa atgatgttag
    12421 agtaactagt gcaggaagtt atgcttctga aatgaataat tcagtaatat ttggttgtga
    12481 atttcctgat ggtagctttg gcaatgtcca tagtgcgaat gaatttgcta gcttagatag
    12541 atttataact gcaataggta tatatgcaga ggcaataatt acattatgta ataaaatata
    12601 aatacaaaat gtcccttata tagacatatt atatatacaa ttaaaatttt acttgatata
    12661 taattgaaat caaagagaag gtgatacaat gataactaag aaacatgcaa taatagtaaa
    12721 gagtttaagc aataaagatg gatatatgac atcaaacgaa ttagctatca aattggatgt
    12781 gtctactaaa actattaaaa gatatatagc agatttaaat agtgttttaa gcaagtatga
    12841 tttggtaata gcttcttcta gaggtatagg atacaagtta agcggttcta aaaacaatat
    12901 agccagagct attaaagaag caaataaata tattgatggt tttttagatg actctgaaga
    12961 gtcaagaatg tcaaatataa tatgtatgct tattaataga aattatatga gtatagaagc
    13021 aatggcagaa gaattaaatc taagtatagc cgctataaat aaattgtcta gtaagcttaa
    13081 aagaaaactt gaaaagtatg acttagttat aaaatctaaa ccttactatg gaagctatat
    13141 acatggtgaa gaaattaata taaggcaatt aattactgac tatgcaataa aattagatga
    13201 aaaaagtaaa gtgaaggtgt ttttagatga cattagtgaa aacgatatac actgtataga
    13261 aagtatttta gaaaagcact taagagaaaa agatacaata atttcagata aagattttaa
    13321 tcttttgctt tcaaaaataa tcgtttctgt atttaggagt aagagaggtc atagtaacaa
    13381 tataaactta atggatacaa gttatagatt tcataactac tactttatag aaaatctaat
    13441 gaaagaaata tctgataaaa ttggatttaa acttattgaa gatgaagtaa tttatatttc
    13501 aaattattct ggtgtaatag cctataaagg tacacaagga agaaaaaaca caagtgaaat
    13561 tgaggaacga ataagtagtg ttataagtag tgcacttcaa gatatattcc ttatttcagg
    13621 tagtgattat acaaaagatg atgagtttat ggttgcaatc tctgaccata taaagagatt
    13681 tttaaataga gctagagcta atgtaaaatc aaataatcct ttgcttcatc aaataaaaga
    13741 gaagtttcct atagctttta atttagccgt gtttttatca aataaactag aaactgagtt
    13801 taatttaaaa cttgatgaag atgagcttgg atatatagct atccactttg ctgcttcaaa
    13861 tgaaagaatg aaaaaaaata ctagtaagaa aatttgtata gtttgtcatt atgggatagg
    13921 aacaggacaa cttatttctg aaaagctaaa acagaatata agtgatttaa gtgttgtggg
    13981 tgtttatcca gttagatatc tcgatatggc tataagtcaa gatgttgatt tgatagtatc
    14041 taccgttgaa ttaaaaggat atgaaaaacc tgtcttatat atagaaaata tatttgatga
    14101 tagcttaatt gaaaacgtaa acaaagcctt ttatgaaaag gaagaaagaa gaaagataat
    14161 aagcaacatg tttgatgaaa aagctttttt cagtataaag gctagtacta aagaagaggt
    14221 cataatttca ctttcaaata aactaaaaga aagagatttt atagaggaaa gttctataaa
    14281 aagtataata gatagagaaa atatttcatc aactgaaata ggaaatctag tagcaatacc
    14341 ccacacaata gtgaagggag ataaaaaatc tataatagga gttggaatac ttgaaaatcc
    14401 aataatttgg gataagcaag aggttcagct agtatttatg gtatttttta atactaaaga
    14461 aaaacataat ttctcgatat ttaaatacct ttataatttt ataaaagatg aaggcggagt
    14521 aagaggaatt attaaaatat gtgactttaa taaattaatg gcactgatag gtaattaagg
    14581 aggaaattaa taatgggaac aaacatattt aacaaagaat atgtattttt aaatgttgat
    14641 gctaagtcaa aggttgaagt tttaaaattt atatcaaaaa aagctaaaga cttaaacttg
    14701 gcagaagatg agagcttagt atatgaaggt ttaatggcta gagaagaaca atttactaca
    14761 aatttaggag aatctatagc aatacctcac actaaaaatg atgcaattga aaatccagca
    14821 gtagtagtat tgaagtttaa tgaagatgtt gtttggaatg aaggtgagga taaggttaaa
    14881 ttagcaataa gcttacttat gccaggaaaa agtaaagaga atattcatct taaattatta
    14941 tcatctcttt caagaaaatt aataaataaa gaatttaaag attctctttt aaaaagtgat
    15001 aatgttgaag aaatatctaa ctcaataaat gaagctttag gtttataatt aaacactaag
    15061 gttataaaat aaaaaaataa ttaactaaaa ataggaggaa tttgaaatga ataaaaaatt
    15121 agtagcatta tgtgcttgtc caatgggact agctcacact ttcatggcag cagaagcaat
    15181 agagcaagca gcaaaggcat taggttatga agcaaaagtt gaaactcaag gtgctgatgg
    15241 tgtacaaaat gagttaacaa gagatgatat attaggagca actatgataa tacatgcagt
    15301 agcaataaca ccagaaggta tggaaagatt tgatggttgt gaagtttatg aagttgaact
    15361 acaagaagct ataaaaaatg cagaaggtgt tataaaagaa atagaagaag atttaggaat
    15421 ataataaatt tattgtggag gaaatagaat ggcaattaag aaaaaagtta taaacagttc
    15481 aggtgcttct acaacaggag gaaataatgt aggaaaatct actccatcta gtccaactca
    15541 atcaaaggga aatggaaaat ggaaagaaat aagtaaacat ataatgacag gtatatcata
    15601 tatgatacca gttttagtaa tgggtggact tataggggcc ttatctcaat taataccata
    15661 tgctatatta ggacttgacc catctgtagg tatagttgat gctatgaact caggagaatt
    15721 tacagggttc aagcttagtc ttttaaatat agcacaatta atgtcaaatt tcggatttac
    15781 tttgtttgga tttgcgatac cactgtttgc agcattttgt gcaaactcta taggtggaaa
    15841 aacagcttta attgcaggat ttataggtgg atatatagct aataaacctg taggtgtacc
    15901 acaattcgtt gatggacaat ggactgaagt tgttccagtt gcatcaggat ttttaggtgc
    15961 aatactaata gcatttataa taggatattt tgtaaaatgg ttaaataaat ctataaaagt
    16021 ttctcataac tggttagctt ttaaaacaac atttttaata ccattaatag cgtcattagc
    16081 ttgtatggta ttgatgatat ttataataac tccatttggt ggattaatta atgaaagtat
    16141 gaaaaacttc ttaacagcag caggagcagc tggagaatat gtatatgcaa cagctttggc
    16201 agcagctaca gcattcgact taggaggacc aataaataaa gcagcaggat tcgttgcact
    16261 tggtttaact acagagaatg tacttccaat aacagcaaga acaatagcta tagttgttcc
    16321 tccaattgga ttaggattaa caacattatt agataaaaga ttagtaggaa gaagagtata
    16381 tgatagacaa ttctatcaag cgggaaaaac ttctatattc ttatcattta tgggtatatc
    16441 tgaaggagca ataccatttg cacttgagag accaggtttt gttatacctt taaacatagt
    16501 tggaagtgta ataggagcta ttacaggtat aattctagga gcaattcaat ggttcccaga
    16561 gtcagctata tgggcatggc ctctagtaga taacttattt ggatatataa taggtatagc
    16621 agttggtgct atattcatag cagtaggaaa tatattctat agaaataaat taataaaaga
    16681 tggtaaactt gttgtagatt atatcgacta gtatttaatt tttactatct ataaataact
    16741 ttggctggta atatggtttt aatcaatatt accagcctta cctatatgat taattaaagg
    16801 cggtggagat aagatatgga taagatagaa aaagtaagag agtattttag agaatatgat
    16861 atagatggat ttcttataaa tagtcctaca aacaagtttt atgttggaaa tttatttagc
    16921 tcttcaggtt atgtttttat aacgaaagaa tcacaatata taatagtaga ttttagatat
    16981 tttgaagaaa ttaaaagaaa atctagtttg tttaatgtag tattaatgga caaaactaga
    17041 actcattttg atataattaa tgatatttgt agagagcaga atataaagga aattggattt
    17101 gagggaaatg aagtatcttt tgatttatat agaagtatga gtaataagtt aagtgcaacc
    17161 ttaaaatcag ttgatttatc tacattaagg gaaacaaaaa atgaagacga aataaaatat
    17221 ataaaaaaag cttgtgaaat agttgatgct acattttatc atatagtaga ctttataaag
    17281 gttggtatga ctgaaaagca agttgaaaat gaaattgtta gaattataaa agctttaggt
    17341 ggtcaaaaag aatctttcga tacaatagtt gcatctgggc ttagaggagc attacctcat
    17401 ggaaaagcaa gtgaaaaagt tatagagtat ggagattttg ttacttttga ctttggtgct
    17461 aagtataata attattgttc agatattacc agaaccattt gtatgggtac tataaataaa
    17521 gagttagaag aaatatataa tatagtaaga aaagctaatg aagagtgtat aagggtttta
    17581 agaccgggaa tgactactgg agagatagat aaagttgcaa gagacataat tggttcatat
    17641 ggatatgcca ataattttgg tcataatctg ggtcatggtg taggaattat ggttcatgaa
    17701 tatcctgcat tagctcctga atcaaatgaa gtattaaaag aaggaatgat tgtaactata
    17761 gagcctggta tatatgttcc aagtcttgga ggcgtaagaa tagaagatga tgtacttata
    17821 acacaagatg gatgtatgag attgactaca tctactaagg atttaatagt tgtaagctaa
    17881 aaataaatta gataaatatt ttataacaat aagaaaagaa gaggtaaatt taaatgtata
    17941 attttgatga taaaccagat agagtaagtg aaaagtgtag aaaatgggat ttaaatatta
    18001 taagagataa atttggagat attagagaag attttgtacc aatgtggatt gctgatatgg
    18061 attttaaaat accaacagaa atagaaaaca aatttattga agctgtaaga agaggtgtat
    18121 ttggatatac atactgttat gatgaatttt atgattcagt tattggttgg caaaaaaata
    18181 tgcatgaggt aaatgtagaa aaagaatgga ttacattaac ttatggaact gtatcaacac
    18241 ttcattatgt agtacaagct ttttgtaaga aaggtgatag tataatatta aacacaccag
    18301 tttatgaccc ctttgaatca tcagcaaaaa aacagggtgt aaatgtaatt tgtaatacac
    18361 tagatgttgt aaatgataga tattatataa attttgataa attagaagtt caaattaaag
    18421 aaaataagcc taaattaatg atgttttgta caccacataa tccatccgga aggatatgga
    18481 caattgaaga aatgacaaga gtagcaacta tatgtaaaga aaataatgtt attttggttg
    18541 cagatgaagt acatgcagag catattcatt atggtaaatt taattcaata cttaagattg
    18601 gaaaagagct tttagaaaat gttattctac tgacatcacc aaataaagga tttaatcttg
    18661 gtggattaaa gacttcttat tcaatagtta taaataagga tataagggac aaatttagaa
    18721 ataaattaaa gcaaaattct ataacttctc caaatgtgtt tggaataata ggattgataa
    18781 ccgcttataa tgaatgtcat gagtggttaa gtggtgtaaa tgaatatata aaatcaaatt
    18841 atgaactttt agaaacttgg gtaaataaat ataataagat aaaattgatg aaaatggaat
    18901 catcttactt agcttggatg gatataagtg gattaggtat tagtgcaagt gagtttacag
    18961 ataaattggc tatagataca ggagtattat tagaagatgg aagtcatttt gtaaaagatg
    19021 gtgagaagta tgttagaata aatttaggaa ctcaaaagga aaatgtaatt gaagccttaa
    19081 atagaatgga tttattttta aagtctttat aaaaatttgg ttgaattagt attttatata
    19141 aatttaaact attaatatgg tatatacata agtagaattt gttttagatt acttaagtat
    19201 ataccatatt ttatataaaa attaaatttg cattagtcat gtgataacta tttaaattca
    19261 tatgtatttt gtatgtataa tagatataat tattatttaa acttattgtt tatttaattt
    19321 ttcaatagaa aaagatttat ctgtaagttt aaaattatct tttataccct tagttaaata
    19381 tactttctta tccttagtta tgaatatagc atctacatta tcaattttat taattaaatc
    19441 catacctttt tcaagaccaa gtccaaatgt agaagtggat aaggcatcac aattaataga
    19501 tttatcagag attattgtaa cactacttaa attgttttca aaaggatacc ctgtaaatgg
    19561 atttaacata tgatgatata tttttccgtc tttttcgata aatctttcat aaattccaga
    19621 agtaacaaca gacttatttg tagtttctat gtttcctatg gattcaccat ttttactagt
    19681 tgggtcttga atgcctattt taaaaggttt atcattttta ccatcttcta aagtaaatat
    19741 atttcctcct aagtttacta aacctttttt tacatcctct gattttaaat aggctacaat
    19801 tttatcagca gcatatcctt tagctatggc acctaaatca attttcatat tttctttggt
    19861 taattttata gatttatttt tttcatccaa tatgatgttc ttataatcaa taagaggcag
    19921 aagtttttgt atctcagaat cacttggaac tttagcttta tctgttccaa tagcccataa
    19981 atttgataat ggaccaattg ttatgtcaaa atatccatct gataatttgg aatattgtat
    20041 agcttctttt acaacgaaaa atgtatcatc agaaactctg acaaattttt taccagcatt
    20101 atcatttatt ttagaaacat cacttcctgg tatatgagtg ctcattttgt tgtcaatata
    20161 tcttaaaatt gaatcacatt catttaagat tttatcactt ttggattctt ttacattaaa
    20221 tacagtaact tcgtttactg taccaaggta gtagctagtt ttactatatt tagtattctg
    20281 gcttgaactc ctaaaaaatg aaaataaaat taatgctaaa atcaatatca caaaaataaa
    20341 tgtgattttt ttcttattca tggtatattc ctcctatgaa attgtgttat tattttatta
    20401 taacataatt tcataggagg acaaaaaatg aagaaaaaag acattcttct tattttaggc
    20461 attttggttg ttattacagc atgttatggg ataataaatg ttataaattc taaaaatgct
    20521 ggaaatattg agatttatgt agataataaa ttgtataaaa ctgtttcaat aaatgccaaa
    20581 gaagaattta aaatagagaa tagagggggg tataacatag taaagattca tgataaaggg
    20641 gttgagatag tagatgcttc atgccctgat aaggtttgcg tacatactgg atttataaac
    20701 aagccaagtc aaagcatagt ttgtatacct aatagagtga gcataaaaat aaatacaaat
    20761 gaaaagaatg ataatcaaga agatataatt tctaaataaa ataataaaaa taattgaaag
    20821 gaattggtga taattatggt taacttagga aacgattggg atgaattatt gaaagaagaa
    20881 tttgaaaaag attactactt aaacttaaga aaatttctta tagaagaata taaaacacgc
    20941 caaattttcc caaatatgca caatatatat gaagctttaa aacacacttc atacaaagac
    21001 acaaaagtct taatattagg acaagaccct tatcatggag ataatcaagc tcatggttta
    21061 gctttttcag ttcaaccaca agtgaaaact ccaccatctt tattaaatat gtataaagaa
    21121 ttaaaagatg atttaggttg ttttatacct aataatggat atttaatgcc ttgggcagac
    21181 caaggagtgt tacttttaaa tactgctctt actgttagag cgcatgaagc taattctcat
    21241 aagaacaaag gatgggaaat tttcactgat agagtaatat ctattttaag tgagcgtgaa
    21301 gacccagtta tttttgtact atggggaagt aatgcacgta aaaaagtaga gttgattgat
    21361 acaagtaaac attatatttt ggaagcacct catccaagcc cattgtcagc aagtaaaggc
    21421 ttttttggat gtaaacactt ctctaagata aatgaaattt tgaaaaagct aggaaaagaa
    21481 cctattaatt ggcagataga aaatatataa aagtaaaagg taacaaaatg ataacaaaac
    21541 aacaataaac aatgacattg ttgtaactaa tagaaatatg cttaaatggt tgaaaaaact
    21601 atgtatgcat atttctattt ttttgtcaag ttgacaactc ttgaaaaaat agttacaatt
    21661 tagttacaca aaaaacacaa ataaaaaaag aaacttacaa agcagaattt tatgaagcaa
    21721 aatatatagt gtaaaaaatc ttagggagga aattttatat gaattttaaa aaattgagta
    21781 atgctaaagt ctcggtaatg gcagttgttt tatcagttgg aatattatcg ggatactctg
    21841 cgcttaataa acaagtaaca ttagtagtaa ggggagaaga aagaactata tcaacattta
    21901 gttctaatgt aggagacctt ttagaatctc aaaacattag ctatgatgca aatgatatag
    21961 taactttaga tgaaaataca aagttatcta atggagataa aatagaagta attgatgtaa
    22021 aggaaaaaac agttgtagaa actaaagaca ttccatttga agttacagtt gttgaagatg
    22081 gctctttatt aaagggtgat tctaaggtta aagaagaagg aaagtctggt aaaagtgaat
    22141 taatatataa agaaacttat cacaatggaa agaaagtaga aaaggaattt gtgaaaaagg
    22201 ttgttaaagc tgagccagta aataaggttg taagcaaagg gacaaaggta gaaatgcaag
    22261 tagcctcatc aaggggagaa agttcaagaa gaatggcttc atcatcatct agtagcagta
    22321 gtagtaacaa tggtaaaaat atgagagtgg tagcaactgc atatactggt cacagtataa
    22381 ctgcaacagg aacaaaacct aagtggggaa caatagctgt agaccctaag gttataccat
    22441 atggaactaa agtttatata cctcaatttg acatggtgtt tactgcagaa gactgtggtg
    22501 gagcaataaa aggaaataaa attgatatct acatgaatga ttcaaaaaca gtttataact
    22561 ggggaagaaa aactatagat atacgtatat taaaatagtt aaataattta tatttttact
    22621 ggaaattata ttttgattat atagagaaga aactctttat agattctaaa aatataattt
    22681 ccagtttttt attttggata tgtaataaaa caggtaaatt ttaaccatgt atagataaaa
    22741 gctatttaaa ttataattta ctatcatata aatctataaa aattgttgca aagagtcaaa
    22801 atatatgata ttatagattt cgttgagaag gatttcatta tgggagtgga tgggtgccgg
    22861 tgtgccctct agtcttcaaa actagtatga ggggttaaga gcctcttagg tgggttcga
//
LOCUS       DAEOTL010000061        22766 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEOTL010000061 DAEOTL010000000
VERSION     DAEOTL010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22766
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.061"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            63..1019
                     /locus_tag="KRH82_002708"
     CDS             63..1019
                     /locus_tag="KRH82_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBG8655978.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1196..1351
                     /locus_tag="KRH82_002709"
     CDS             1196..1351
                     /locus_tag="KRH82_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8655979.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            1481..2494
                     /gene="aroF"
                     /locus_tag="KRH82_002710"
     CDS             1481..2494
                     /gene="aroF"
                     /locus_tag="KRH82_002710"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBG8655980.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2516..3580
                     /locus_tag="KRH82_002711"
     CDS             2516..3580
                     /locus_tag="KRH82_002711"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBG8655981.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3580..4893
                     /gene="aroA"
                     /locus_tag="KRH82_002712"
     CDS             3580..4893
                     /gene="aroA"
                     /locus_tag="KRH82_002712"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBG8655982.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELNKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4871..5950
                     /gene="aroC"
                     /locus_tag="KRH82_002713"
     CDS             4871..5950
                     /gene="aroC"
                     /locus_tag="KRH82_002713"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBG8655983.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            5953..7149
                     /gene="pheA"
                     /locus_tag="KRH82_002714"
     CDS             5953..7149
                     /gene="pheA"
                     /locus_tag="KRH82_002714"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBG8655984.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRFIDNDGEQKIEFSLDS
                     SNKNFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7196..8005
                     /gene="aroE"
                     /locus_tag="KRH82_002715"
     CDS             7196..8005
                     /gene="aroE"
                     /locus_tag="KRH82_002715"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBG8655985.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8017..8550
                     /locus_tag="KRH82_002716"
     CDS             8017..8550
                     /locus_tag="KRH82_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBG8655986.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            8571..9410
                     /locus_tag="KRH82_002717"
     CDS             8571..9410
                     /locus_tag="KRH82_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBG8655987.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNKNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9678..11159
                     /locus_tag="KRH82_002718"
     CDS             9678..11159
                     /locus_tag="KRH82_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBG8655988.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11192..14629
                     /locus_tag="KRH82_002719"
     CDS             11192..14629
                     /locus_tag="KRH82_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBG8655989.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYQR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENTKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNGLENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCYKSLLKSDR
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14647..15393
                     /locus_tag="KRH82_002720"
     CDS             14647..15393
                     /locus_tag="KRH82_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBG8655990.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15342..15662)
                     /locus_tag="KRH82_002721"
     CDS             complement(15342..15662)
                     /locus_tag="KRH82_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBG8655991.1"
                     /translation="MKKIMNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIV
                     KYKTSYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAK
                     NSLV"
     gene            16450..20592
                     /locus_tag="KRH82_002722"
     CDS             16450..20592
                     /locus_tag="KRH82_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBG8655992.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPDGNYRIVEAFGTTGGVPTPGDFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDVPASIVNPEYSLDGGVTFQPWTGSLNIGTLEVGETR
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNASTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTTVPGETFSYTITVTNLGPSAAQSIVLIDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWTGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNI
                     AEVTSTAPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCYCNCCKNDF
                     WC"
     gene            21047..21394
                     /locus_tag="KRH82_002723"
     CDS             21047..21394
                     /locus_tag="KRH82_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBG8655993.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(21543..22592)
                     /locus_tag="KRH82_002724"
     CDS             complement(21543..22592)
                     /locus_tag="KRH82_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8655994.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKGESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKVGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
BASE COUNT         9131 a         2558 c         3721 g         7356 t
ORIGIN      
        1 ataattacag taaggattat aaaaaatttt tagaatgtaa attgaaattt aggagtagat
       61 gtatgtatat actgaattta aatacaagag agactattga agattttaga gataaatttt
      121 atgtagcaga aaattcttat cttatattaa gtgctccaaa aaatttaaaa ttgcttaagg
      181 aaactttgga tatagatgaa ataactttta atgattgtct taaatttgat gaaataacca
      241 aacttgattt atttgataat tacgattttt taagcctaaa tacatttgaa ctaagagatg
      301 gagaagctgt tatagaagag gtaaatatgt atttatcaga taattttata ttggttgtag
      361 tgaatgaaga acacttttta tttgaatttg taaaaaatat tattttgaag aactctcaac
      421 ttgaaaaaaa tccagttatt aatctattta agataaacta cttgattctt agagaagtta
      481 taaaaaatgg ttttgagtct ttggaaaaag ttgaagagtt aattcttcaa atagaagatg
      541 aaatgatgga caacattaat aagaatcatg tatctagaat aagtgatgta agaggattaa
      601 caagaattat agttaagaat actagacctc ttttgtatat tggggataga atagttaagg
      661 aaaatataag atatttaaaa tattcaaatg taaaaaaata taatttagaa aattttcaag
      721 gtatagattt tggaattgac aaattataca atttcgcatt gtcaacacga gagttagcag
      781 ataaattatt agatatttat tcttccagag taggtgagaa aacaaataac ttaattacaa
      841 aattaacctt gttaacagcc atatcagcac cacttacaat tataactggt atatatggaa
      901 tgaactttag atatatgcca gaattaaact ggatttatgg atatccagca actttatttt
      961 ttatgctatg tataattttt gttggaatta taatatttaa aataaaaaaa ttattgtaaa
     1021 ttacagatga tgtttaattg attttataaa aatacatcaa ttgagaagct gatttaagta
     1081 aataaaaaaa tattttaaat tgaaaatatt tatagaaaat attgacaatt atattttctt
     1141 tgttataatt attaaacaag aagaataata aattataaaa atggaggata atactatgaa
     1201 aggaatatta aaagaactaa cagcaaaact ttatagcttt ttttacttta tgttctgggg
     1261 cttttatttt agcgctggct atttctttta caaaaatata tgtacttcct ttctggtgag
     1321 gccttatttt agtgattttg agcataagta aattttataa aaatgattat tttatatatt
     1381 tatataagat ttagtgcttg atagattatt ttagagaact cattagtgag ttctcttttt
     1441 tattttaaat ataaaattat aatattggga ggtagtaaaa atgatagtag tattaaaaat
     1501 gggagcagat aaaaatgaag ttaaaaaatt aattgaggct attgggagag aaggagtaga
     1561 agttaatccc atagatggaa cagaattaac tgttttaggt ttagttggag atactagtaa
     1621 aatagatgcc aaaagaatag aagcaaataa ggtagttgaa aaagttatgc atgtggtaga
     1681 gccttttaaa aaggccaata gaaaatttca tccagaacct tcaatcataa atgttaatgg
     1741 aatggaaatt ggttcaaaga aaattgctat gatagctggg ccttgttctg ttgaaacaga
     1801 agaccaaata gtatctatag ctaaagatgt gaaaaaatca ggtgcaggat ttttgagagg
     1861 tggagcattc aaaccaagaa catcaccata cgctttccaa ggattgaaat atgatggatt
     1921 ggatttatta aaaaaagcaa aagaaaaaac agggcttcct atagttacag aaataatgtc
     1981 aacacaagat atagatatat ttgaagaaaa tgtagatgta attcaagttg gagctagaaa
     2041 catgcaaaac tttgatttat taaaagaatt aggtaaaaca aataaaacaa tacttttaaa
     2101 aagaggatta tctgctacaa ttgaagagtg gctaatgtca gcagagtata taatggctgg
     2161 aggaaatgaa aatgtagttc tttgtgaaag aggtataaga acttttgaaa catatactag
     2221 aaatactttg gatttaagtg caattttagc tgtgaagaaa cttagtcatt taccagttat
     2281 agttgaccca agtcatgcag caggtaaatc atggatggtt gactctttat ctaaggcagc
     2341 aattgcagtt ggagcagatg gtctaataat cgaagttcat aatgacccag cacatgcact
     2401 ttgtgatgga aaacaatcga ttaagccaaa tgaatatgat gaattgataa gtgaattaaa
     2461 gactatcgca tcagcagttg gtagagaaat ataatctata aaaggatggt taaacgtgga
     2521 agaaaaacta ttagtaaatt taaaagaaaa tagctacaat atatttatta aaaaaaatat
     2581 actaaagaat ataggagaag aaataaaaaa aatatatttt ggaaataaga tttttattgt
     2641 aactgatgaa aatatagcaa aattatactt ggataaagta aaaaataatt taagtgaatc
     2701 tggatttgaa attaaatctt taatattaaa atctggtgaa gaaacaaaat catttaatac
     2761 tcttcctaaa atatacgata gtttacttga ctttaagtta actagaaaag atttgattat
     2821 tactttagga ggaggggtaa taggtgattt aggtggattt gcagcagcaa cttttttaag
     2881 aggtataagt tttattcaaa ttccaacatc tttattagca caagttgata gttctgtagg
     2941 tggaaaagtt ggagttgacc ttgagagagg caaaaactta gtgggaagct tttaccaacc
     3001 aaaggctgtg tttatcgacc caaatgtatt attatcactt ccagaaaaat tctatagaga
     3061 tggaatggca gaagttataa aatatggatg tataaaagac aaaacttttt tcaataaact
     3121 tttaagttta aaaaatagag aagaagtaat gcaacatata gaatacatta tacataaatg
     3181 ttgctttatt aaaaaaactg tagttgaagc tgatgaaaaa gactttggag atagaatgct
     3241 tctaaacttt ggccatacat taggtcatgc tattgagaaa tactacaatt ttacgggtta
     3301 tacccatgga gaagctgttg ccataggaat gtataagata actttagaaa gtgaaaagat
     3361 aggaattaca aaaaaaggga catcagaact tataaaatca attttaatga attataattt
     3421 gccttatgag attgaattaa gagataataa atctatagta gatgctatat ctcttgataa
     3481 aaaaaatcta ggtgatacat taaaaataat acttttaaaa gatattggag agagtattat
     3541 atataatact acttctaaat tttttcagga ggtaagataa tgggaagtct aaaaatatat
     3601 ccaagtaaat tatctggaga tgtaaaaata ccaccatcaa aaagtatggc acatagggca
     3661 gttatttgtt catctctaag caatggaaaa agtagaattt ctaatataga tttttctgat
     3721 gatataatag ctactataag agcaatgaca tcattaggag ctattataga aaagaaagaa
     3781 gatattttag aaatttcggg aattttttct aaagaaggta ttttaaatag agagaatcag
     3841 ttgaatcaac ctaaattgac aatagattgt aatgaatcag gctctacatt gagattttta
     3901 gtacctatat ctttagcatt tgatggtgta aaaaggttta taggtagagg aaatcttgga
     3961 aaaagaccac ttgatactta ttatgagata tttgacagac agaatataaa atatagttac
     4021 aaagaaaatc agttagattt gattatatca ggtaagctta aaccagatga atttagagta
     4081 aaaggaaata taagttctca gtttatcaca ggtttactgt ttatattgcc tacgctagag
     4141 agtgattcaa agataataat tactactgag ctagaatcta aaggatattt agatttaact
     4201 ctttcaacga taaaagattt tggggtagaa attataaaca ataactataa agaatttatt
     4261 ataaaaggaa atcaaacgta taaagcgaga gattataaag tagaaggaga ttattctcaa
     4321 ggagcatttt atttatcagc agatgctata ggagaagata ttagcatatt agaccttaaa
     4381 gaagattctc ttcaagggga tagtgaagta gttgaaattt tatctaggat gggaatggaa
     4441 atattaagag aaggcaacaa aataaaagga ataacaaatg gtttaaatgg tactttgata
     4501 gatgcatctc aatgcccaga tataatacct gtattatctg tagtagcatc cttaagtata
     4561 gggaggacta caataattaa tgctggtagg cttagaatta aagaatgtga tagacttcat
     4621 gcaataaatg ttgagttaaa taaacttgga gcaaatatag aggagaaaga ggatagtttg
     4681 ataatcgaag gagtaagcaa gttaaatggt ggagtagagg tgtggagtca caaagaccat
     4741 agaattgcta tgacacttgc aattgcttct tgtagatgtg ataaaccaat aatattaaaa
     4801 gattttgagt gtgtatcaaa atcttatcca cattttttta aagattttaa gatgttagga
     4861 ggtcgaattg atgagtggaa tatggggaaa taatttaaaa gtatcaattt ttggagaatc
     4921 tcatggaaat gctataggta taaatataga tggtcttcct tcggggattg aacttgacct
     4981 tgataatatt gataaagaaa tgaagagaag agcacctgga aaaaattcta tatctacttc
     5041 aagaaatgaa agtgatatac cagaaattct aagtggatat tttaatggaa gaactacagg
     5101 aacgccatta tgtgcaatca taagaaatag tgatactcgt tcaaaagatt atggagagct
     5161 taaaaactta atgagaccag gacatgcaga tttcacaggt aatgtgagat attctggatt
     5221 taatgactat agaggtggag gtcatttttc aggtaggata acagctccat tagtattttg
     5281 tggggctata tgtaaacaaa ttttatcaca aaaaggaata gagataggag cacacataaa
     5341 aaaaattaaa aatatagaag atatgagttt tgattatgta aatatttcaa aacaacagtt
     5401 atcaaatttg caaactttgg aactaccttt acttgattta tcaaaggaag aagccatgaa
     5461 aaatacgatt atagatgcaa aaaatcaagg agattcagtt ggtggtataa ttgagtgtgc
     5521 agtagtaggt attaatgtag ggcttggaaa tccatttttt gactctgttg aatctacttt
     5581 atcacattta ttgttttctg ttcctgctgt aaaaggtgta gagtttggtt taggttttga
     5641 acttgcagat atgtatggct ctcaaagtaa tgatgaaatg tattatgaag gaaatcaagt
     5701 taagagcaaa acaaataaca atggaggaat tataggaggg attactactg gaatgccaat
     5761 aattttcaaa gtggcaatta agccaactcc atcaattagc agacaacaaa acacagttaa
     5821 tataaaagat aaaaaggacg atattttata tattaaaggc agacatgacc cttgtatagt
     5881 tcaaagggct atacctgtaa tagaagcagt aacagccatt ggaatttttg atttgatgaa
     5941 aggacgataa taatggagga tttaacgaga tatagaaatg agattgacaa tatagataaa
     6001 gagcttattc aattatttga aaagagaatg aatacagttc ttgaaattgc cagacataaa
     6061 atgaaaaata acactactat acttcaaaaa gatagagaag aaaaagtact aagtagagcc
     6121 gtagataatt tagataataa agcatattca caagaaacgg tacagttttt taattctata
     6181 atggaaatta gtagaggatt acaaaaaaga tttatagata atgatggtga gcagaaaatc
     6241 gagtttagtt tagattcatc aaataagaat tttgatttgt caaatgtaaa taaatataag
     6301 tctttaaaag atgaattaaa taaaaaaaat atcctagtag gctttcctgg aaaatcaggt
     6361 tcatttacag aagaagcact aaataaattc ttcaacaaaa aaatatcaaa aaaacaattt
     6421 aaagaatttg aagatgtttt catagcactt aaaaataaag aaataaacta tggaataatc
     6481 cccatagaaa attcatctac aggagctatc tctgaaactt atgacctttt gagaaagtac
     6541 ggtttttata tagttggaga agaatgtata aaaatagacc aaaatttaat agggataaaa
     6601 gacacaaagc ttgaagatat aaaagaaata tattctcatc cacaaggtat aggacaatgt
     6661 agtgaatttt taaaacaaaa tagtacatgg aaattgatac catttaataa cacagcaaca
     6721 agtgcagaac ttgtaagaaa acttcaagat aaaacaaaag cagcaattgc aagcaaaaaa
     6781 gctgcaagta tttatggatt agaaataata agtccttgta taaatgatat agcaaacaac
     6841 tatacaagat ttgtagtaat cagtaatcaa atacacattg aagaagaatc aaacaaaatg
     6901 agtgtagtat tttctgttga acatgaagca ggaaaacttt ataaagtact tggatacttt
     6961 gctaaaaata atataaatat gacaaaaata gaatcaagac ctatgaaaaa tgcctcatgg
     7021 agatatttct tttatataga ttttgagtgt tctatataca atgctaaagt gtacgattta
     7081 ttagaattga tagaacataa tacagcatat tttaaattta tgggagtata taaaaataaa
     7141 actgaataga taagataaat ttttatttaa tttataatta ttaggaggtg taagtatgaa
     7201 ttttttcggt ctagtaggtg aaaaactctc tcacagtgtt tcacctcaaa tccacaagag
     7261 agtattcgag atattgaata ttgaaagtgc ttataaaaac tttgaaattt caaaagaaga
     7321 tatatctaag ctagacggtg ctataaaatt attaggaata caaggggtaa atgttactgt
     7381 accatataag gagcgtatta tgaaatatct tgattttata tcaccagagg caaaacgtat
     7441 aggagcagtt aatacaattt tactcagaga aaatatgtta tatggttaca atacagatta
     7501 ctttggtctt gatagtatgt ttaaaatggc taatattgat gttcaaggaa aagtagcagt
     7561 tatattagga actggaggtg cttctaaagc tgctcttaca tattttattg attctggtat
     7621 agaaaagctt tatgtttcaa ctagaaaaaa ggatgataaa aaattattaa atagtaaagc
     7681 tatattaata gattatgaag aacttaaaca tataaaagga gatataatat taaatgctac
     7741 accagtaggt atgtacccta atgtaggaat ttcaccagtg tcaaaatcta ttatacaaaa
     7801 ttttgatata ttaatagatt taatttacaa tcctggagaa acagagtttt taagaattgg
     7861 taatagtatg ggtaaaaaaa cttgtgatgg attatatatg ctggtggggc aagcaataaa
     7921 atctcaggaa atttggcaag atactaaaat agataatagt attttagatg ttatatataa
     7981 tgaactaaaa ttagaatttt tgtaagggag attgttatga taaataaaac aaaagaaaaa
     8041 ttgatattaa taggtatgcc aggtagtgga aaaactacaa ttggtaaact tttggccaaa
     8101 gaatataatt gtagtttctg tgatatggat gattatataa ttcaaatatc tcaaaaaagt
     8161 atagcagagt tgttttcaga aggagaagat atctttagga actatgagac tcaagcatgt
     8221 agagaacttt ctataagtga taaaacagtg atatctacag gtggaggtgt aataaaaaag
     8281 gatgttaata tggaaatact aaaagaaaca ggtataataa tttttattga tagacctata
     8341 caaaagattt tggaagatat aaatattaat tcaagaccat tattaaaaaa cggaaaagat
     8401 agattgtata atctttataa tgagagaata aatctttata aaaaattttc agatatagag
     8461 attttaaatg ataaatcatt aaataatgct gtatataata ttacaaatgc agtcagtgaa
     8521 aattttaaat ttgactttaa agaaaaataa tctaggggga agtaaaaata atgaatattg
     8581 ttattgtagg actaggagtt ataggaggct cttttgctaa agcattaaaa aaagctggat
     8641 atgaaaatgt atttggagta gatgtagatt tagaaacttt aaaaaaagca gaaaaagcaa
     8701 aaatcataaa aaaaggatgt actacaggta aagagttatt taaaaaagct gatttaatta
     8761 tactatctat atatcctaga ttagttgtag attttctaaa taagaataaa aactttttta
     8821 aaaaagggac tataattact gatactacag gaataaaaga aacacttatc aatgatgtgt
     8881 tgcaaattat tccagatgat atagatttta tatttggaca tccaatggca ggtagggaaa
     8941 aaaagggtat tgattttgca agtgaacaag tttttaatgg tgcaaattat ataattactc
     9001 caactggcag aaacaacata aaaaatttag agttagttga aaatttaatt ttagagattg
     9061 gatttaaaag agtaaaaaag ttaacttcac aaaaacatga tgagattata gcttttactt
     9121 ctcagttacc tcatgttatg gcagttgctc ttataaatag tgatgaagaa ggtagagata
     9181 cgggtaaatt tattggagat agttatagag atttaactag aattgcaaat atgaatgaag
     9241 acttatggag tgaacttttt ttaggaaata gagataattt actaaaagtt atagaaaact
     9301 ttgaatcaga agtaaattta gtaaaagaag ctatatttaa caatgataaa aataaattaa
     9361 tagagtattt taaaaaatca tcaataagaa gagaagcttt agaaaaataa atattaatat
     9421 ttaagctata tatagatggg tataaatata agcgatagtg tatttaattg tattaataaa
     9481 tatggattca atataattaa atatgctatt gatatatttg tacccttaac tattgttatc
     9541 ttttaaatga taatgatatt tatttaaata ctctttatta acaatttata aaacttaatt
     9601 gtaaaaaata cttattaata gtaaaataaa gtgaatcaat tatattataa ttgctaaaga
     9661 gagtgaggtg tagctatttg aaaaaaaata gattaatagc aaagaatata tcaatagcat
     9721 ttatagtact attctttttt agtgtattta cattttttta tgtaggtaat attaatagag
     9781 tgttagaata tgaaacaaat gacataataa cagttacaat tgctggatgg attatacttt
     9841 catttttatt tttaggtatt ataatttaca tattatattc aaaagcaaat agtcaaaaaa
     9901 ctatagaaaa agtagcatat acggattttg taacaggtta ttccaactgg agaaagtttg
     9961 aattagatgt tacaaattta ttaaagaaaa catcacaaaa taataaatat gcaatggtca
    10021 tattcgatat tgataaattt aaagcaatta atgatatata tggccataaa aagggaaatt
    10081 taatattaaa agatattgca gatactttaa atgaattgac tgatatcaat gaaacttttg
    10141 ctcgtgtaag tgctgataat ttcaatatat tattaacata taacaaaaaa gaggatataa
    10201 taaatattat caaaaagatt atggcaaata atgaacttgt aaacttatct tttggaattt
    10261 atgaaatcaa agataaggat ttatctgtaa gtgtatatag tgatagagct tcacttgcaa
    10321 aatcatcaat aaaaaataat agtgatgtaa attttgcatt ttttaatgac aaattaagag
    10381 agaaattatt atttgaagat aagatagaaa aagaaatgga atatgctctt gaaagtgggc
    10441 aattcgtaat gtatttacaa ccaaaataca atattaaatt agataaattt tgtggaagtg
    10501 aagccctagt cagatggcaa tatacagaaa aagaggtcat atatccaggt gattttattc
    10561 ctatatttga aaaaaatgga tttattagaa agattgatat gtacatatta gaacaagctt
    10621 gtaaagaaat ccggtcttta tttgataaag gaatttcacc tttacctata tctgtaaact
    10681 tctcaagagt tgattttttt aaaaaagatt ttattgaaaa catagtaaat atatgtgata
    10741 gatataaaat accatatagt ttaatagaaa ttgaaattac tgaatctagt atgtttggag
    10801 atactgatac tctatttaat gttagtagaa acctacagga tattggcttt atagttgcaa
    10861 tggatgattt tggctctgga tattcttctg taaatatgct taaaaatata ccattaaatg
    10921 taataaaatt agatagagga ttttttgttg atgataaaga tgttgataag agtcaaattg
    10981 ttataaaaag catagtttct ctcattaagc aattaggaat aagggttgtt gctgaaggaa
    11041 ttgaaacaag aagtcaaata gaaatgttaa aaaaagcaaa ttgtgatatt gttcaaggat
    11101 attatttttc aaaaccatta ccaattaaag aatttgaaaa attagtctat aaaatatagt
    11161 cagcgagtct taaatgggag gtggtgatta agtgataaga gcaaaatcgt taaaaaatgt
    11221 actgagtatt gttttaatat ttttatttac aataatttct ttttctgatt ttgcatttaa
    11281 aactaatgtc caggaagaag aaaatagtaa aattaattta agagaaatat ccctacaaag
    11341 ttccaatgct ataaaaataa aattagatag ttctctatcc tttattaaaa gtgtggcaaa
    11401 tatggtttct tattttaata ctatagataa ctcaaaaata gttccattat tagctaatat
    11461 atcaaaagaa tctgactttc aaagaatctc tattgtatct cctgatggaa taagtcatac
    11521 cagtgatggc aaaattatca atgtgtcaaa gtatcagtat tttaagaaag ctattaaagg
    11581 agaaagtaat atatctgaag ttgtgaaatc tccaattgat ggaaaagata cttttgttat
    11641 agctactcct gtatttaata agaataacaa aataattggt gttttatacg gttcttacta
    11701 caatgataaa ttagctgaat ttatagatat aacaagtttt aatagtgaag ggtacataga
    11761 tatatttgaa tctagtggtc aatttgtttt aaaatcttca catacaaaca aactgattaa
    11821 gtcaagtagt aacatatatg atatatttaa aaaagcttct tttgatgatg gttatagcta
    11881 taaaaaaata tatgaagata caaaaaataa caagagtggc tttacctcat atgaatacaa
    11941 aggagaaaat cgttatgcta cttatacacc cattggtgta aatgactggt atgtaatttc
    12001 tgtgatacca caatatactg taagaagaaa cattgataaa ataaatcaat tagcattttc
    12061 tcttattttc aaggtattct tattgtttat tatgcttata atatatatta tttataaaaa
    12121 caataaatct cagaaagata tactaaaagc taacaaagaa atctcatcta ttacaaatag
    12181 cattcctgga ggagtacaaa agtgtaccct gggtgagaca tgcaatatta attttttaag
    12241 tgatggattt atagagttgt ttggttatac aagagaagaa ataaaaacat tgtttaataa
    12301 tgatttttat agtttaatac ataaagatga tgttgaaaga ataaaaaaag aaatttttaa
    12361 acaactttac aaaaataaaa ctgttgaatt agaatatagg attataacaa aaaatggtaa
    12421 tacagtatgg gttttagata aaggggagct tataacagaa cctgatggaa aagagtattt
    12481 ttgttgtgta actgtagata ttactagaac aaaacaatta gaacaagaga tggaacaaaa
    12541 aaatctagaa cttgaaatga tatcagaaaa tgttttaggt ggtataatta taacagaatt
    12601 taatgatgat tttactataa aatacgctaa ctctggttat ctttcaatga ttggatatac
    12661 acgtgaacaa ttagaaaatg aacttaaata caaagcttgt aatcttgttt tttatgaaga
    12721 tagaaagaag gctcttgaaa gtatacaaca tcaattaaac acaaaaggaa tagctgtata
    12781 tcaacataga ataagaagaa gagatggtaa tattatttgg gtttctataa aaggaaggct
    12841 tattgttgat gatgatggta ttgaaaaagg tatttggatt ctaaatgata taacagattt
    12901 aaaaaatgca gaacaaaaac ttaaaataaa tgaagaaaga tttagaattg cattaaagca
    12961 aacatcaaac actatatttg agtatgatat aaaaacaaag tcacttttaa atactagtaa
    13021 agagcttgat aaatataata tttataaaat tactaaaaat gttccatatt ctctagtaga
    13081 atcaggagtt attcataaag attttagtga tgattttata aacatgtatg aaaatgtaat
    13141 aaatggagca aaaaaagcaa gttgtgtagt taagatgaaa cttccagatg aaaattatat
    13201 atggaataaa gttaccttga ctactatttt tgatgaagat ggtaatcctg taagagcaat
    13261 tggtatacag gaagatataa gcaaacaaaa ggaagcagaa ataagataca atcaagaagg
    13321 taagtatcat tcagctatat tgtcggaagc aatgataacc tatgaaataa atgtatcaaa
    13381 ggatactttt atcaaaggaa atgaaagttg gcaaaaacca tttggaatta agcctgacaa
    13441 taactattct caaatggtaa aaactatagc aaatagtatt gtacataaag acaataaaga
    13501 aacattttta aatacatttt tatgtgaaaa cttattggat gcatataaaa ataatgtgac
    13561 tgaaataaaa ttagaatatc aaagaatgaa tcaagaaaat aaaatgattt gggtcatttg
    13621 tacaatgcac ttaataaaag attctattac gaacgatata aaagcacttg cttatgttaa
    13681 agatattgac aagcaaaaaa atgaagaaat tagattgaaa ttaaaagctg aaagagatac
    13741 tcttacagga ttatataata aaggtactac agaaaaattg attaatgatt tcttgaactc
    13801 tgaggaagca agcttaggaa tgcatgcatt tttaattgtt gatatagata attttaaatc
    13861 tgtgaacgat aatttaggac atgtatttgg agataaagta ttatttgaag tttctaaaaa
    13921 cctaaaacct atatttagaa aagatgatat agtaggtcga attggtggag atgaatttat
    13981 agtattctta aaaaatattc agtcttttga gaataccaaa aagaaagcag aaaaaatatg
    14041 cgatatattt agaaattctt atacggaaaa taaaaagaca tataaaatat ctggaacagt
    14101 tggaatttca tttgtaccag aacatggaac tgtatttgaa gaactttata aaaaagcaga
    14161 catagcactt tattatgcaa agagcaaagg aaaagataag tatgcacttt ataatgattg
    14221 tatctaccaa aatggacttg aaaataatat aagtgataat aatataaaat tagcagataa
    14281 atgtgagaaa tccaaaccag tacttaaaga aattcttgat tctattgata attatatcta
    14341 tatagtgaat ccaaatactt atgaacttct ttttgtcaat aataaggtgt ctcgtttgga
    14401 tttagagata aaattaggag aaacctgtta taaatcacta ttaaaatctg atagaccatg
    14461 taataattgc cctcttaacg gattagaaga aaataagcat tcaaaattca aaatagagac
    14521 aaatacattt ggtaaaaata tcagtatagc aagttggatt aattgcatag atggagaata
    14581 caactgtctt atagagtgta tagattcttc tttatacaaa aataaataaa aaaggactat
    14641 gaagatatgt taaatagtat aactttgata cttggtataa tatttacaat ttactatttt
    14701 tatctcaaaa tagtttttgg aggaatttca tttagtgaga ttttcttagt tgtaggaatt
    14761 gtactaatta tctatcaaat atttaagaaa aaaattaaag aaaagaaggt tttttatagg
    14821 gtgttaaaaa taataatcag cattttttta atagtatttg tagttactga gagtctaatt
    14881 attttttatc ctaaaaatag tttagaatca aaaagtgatt atctcttaat tttaggagct
    14941 tctgtaaaaa agactacacc aagtacaacc ctgaagggta ggttagacac tgcattgaaa
    15001 tacctaaaaa ttaatgataa ttgttatgtg gtagtatctg gtggtaaagg aagtggagaa
    15061 aaaataactg aggcaaaagc tatgaaagat tatcttataa aaaatggtat agataaaaat
    15121 aggataatag aagaggataa atccacgaat acttatgaga attttaaata ttcaaaattg
    15181 aagatagaag aacatagtca aagaaaacta agcgatttaa aagtaaaaat agtaacaaca
    15241 gattttcatg ttctcagaag taaaatatta gcatatagaa atggatataa aaatacgtct
    15301 ttttatgcta gtaaatcaaa actttcattt gtaccaactt attatacaag agaatttttt
    15361 gcattatgga aaacaatcat ttttgataga taataaataa aaagactaga tataaactca
    15421 tatctagtct tttctattcc cttaattcta atccattttc caactttact tgttgtagaa
    15481 atttcaacat tgggatttac aagtaattgc ttataagaag ttttatattt tacgattcca
    15541 aaatataatt ttccttcata atccattata aatccgaatg gtcttactct tggtttatta
    15601 tcttcaactg tagcaaaata gaatgttgag ttttctttaa aaaaattcat tatttttttc
    15661 atgattaaat cctctttgta tcttatacta atataatgaa tataaataaa atattcataa
    15721 tactaatata aatcgatata aaaacaatta caatattata ttgattattc aaaattatat
    15781 ataaaattca gaaaaaaatt agtttacata ataaaaataa agtcaactaa aattattgat
    15841 tttagattaa agtaccagat taagcgttta agtagatttt aagcttgatt tgattagaaa
    15901 agtacaaact atcgccgaaa aaaattaaac ccatttaaaa agcaatataa aagcttgtta
    15961 tttttgagaa aaatagaccc tctaaactca attagataaa aataaaatac agaaaattat
    16021 atctctgaat atctcaagta attaatttta aattttacga tattttgttt gatgatttat
    16081 aatataaaag catactctta atctgctcaa attaaaaaga ataaaaaata acaaaaaaat
    16141 cactgacatt tcactgacaa attgtaattt tgttattata aatacattga aaatacttga
    16201 ttattgaaaa atggcataaa ataatacatt ttatgccatt tactattatt tgatagtttt
    16261 taacttatga cataagatat tttttaacat atacaataaa atataaaaaa ttgatattac
    16321 aaataaaaaa aatacatatt agatgttata gaaaaaaagc gcacttatag gcttaaaatg
    16381 tcacataaaa gagttttaaa gaataatata ttatgaacac aaattttgta atcgcaaagg
    16441 agtgataata tggcaacagt atcaggacaa atagtttttg atagaaatag aagtgctacc
    16501 attgattctg gagactcagg aatagccaat ataccagttg tattacaaga tatagcaact
    16561 ggagttagac ttgtggttct cacagatgca tcaggaaatt atgtttttac taatgttcca
    16621 gatggtaact atagaattgt agaagctttt ggaactacag gaggagtacc aacaccaggg
    16681 gattttgcaa cagcgatagt aggtccagtt ccaattgcag aaatgccacc tattagttct
    16741 gtgacaaatc ctcctattgg ttcaacaaac ttagatggta caacacctaa cacactatta
    16801 ataacagtag caggttcaga tataacaaat caaaatatat taaatgggcc tgtgatttat
    16861 acacctatag agaatatatt ggattcttgc gtatctgtat ctaatataaa ccttattaca
    16921 gatgcagata acggaacatt cggttttttt ccaccaggta caccaagtaa tacaggacct
    16981 gaaatagaac cttacccaaa tgtgacgcca gattttacgt atgttgtacc agacccaact
    17041 aagtttacac ctttagatgg agaatataca gtacaaaata ttatgacaaa tgcaatgagt
    17101 aatgttatag gagcttggtg gcgtattgct gaccatacta caggaaatga aacaggaaga
    17161 atgatggtgg taaatggttt taatcctgga gctgtatttt ttaaatcaac agtacaagtt
    17221 acacctaaca ctaattattt atttagcact tggattttaa acctttttaa ggtaacagga
    17281 tatccaccac cacagctagg tgtaagaata tttgaccaaa ataataatat actatatcaa
    17341 gcaacattag gagctcaaat tccagttaat acaaacgcac cagaatggaa agaagtaggt
    17401 actgtgatta attctcaaaa taataatcaa cttacagtag aattttttag tgaaggagaa
    17461 agcgccattg gaaatgacta tgctatagat gatgtttctt taagagaaat agctgttcca
    17521 acttttactc caataaaaac aagtaacaca gaaactgcta atgtaggtga tataatcaca
    17581 tatacagtta cattagataa tacttgtgat agccctttaa ctaatgtatt ttttagggat
    17641 ttaattccaa atggtttaga gtttatacct ggaactgtaa cggttgatgg agtatctgta
    17701 ccaggagtag accctaatac aggtttccca cttccagata ttggaggagg aacaggggtt
    17761 gaagtaactt ttgatgttgt ggttgaaagt attcctaacc caaatcctac taataatata
    17821 gctaatatag attactccta tacacctgta gaaggcggta taccaaatga tttttcagta
    17881 gattctaatc cagttcctgt tgaagtaata tcagcagata ttgaagttac aaaattatct
    17941 gaacctacta tagtgaatcc aggagaggaa ttaatataca ctataaaagt agtaaataat
    18001 ggaccattcc catctgaaaa tgtggtttta acagatgatg taccagcttc tattgtaaat
    18061 ccagagtatt cattagatgg aggagtaact tttcaaccat ggactggaag tttaaatata
    18121 gggacattag aagtaggaga gacaagagtt attataatta ggggtattgt aaatccatca
    18181 acagtaggaa ttataacaaa tacagctgta gtatcttcaa ctacagcaga cccaaacctt
    18241 aataataatg catctacaat agagacagaa gtgaatttat tagcagatat tttagtaatg
    18301 aaaacagcag aacctaattc agctgttcca ggtactttat tgagatatac tattcaagta
    18361 gaaaacttag gaccagcaaa tgctgaaaat gtaatattaa atgatgatat tccagcttct
    18421 attataaatc cagaatattc attggatgga ggagcaagtt ttcaaccatg gaatggaagt
    18481 cttaatatag gtactttaaa ctctggaatt tcattaacag ttttaattca aggaacagtt
    18541 agtttaaatt cttcagaata tatagtaaat acagcaacag tttcttcaac tacacctgac
    18601 ccagatttaa gcaacaatat atctaccatt attacaccag ttaacccaca agcaggtatt
    18661 tctattataa aagtagctga cgaggatgta gctgttccag gagaagaatt tgtatataca
    18721 attgaaattt ttaatgaagg accatctaat gctacgaatg tagttttaac agatgatata
    18781 ccagatgtta ttttaaatcc agaatattca ttggatggag gagcaacttt ccaaccatgg
    18841 actggaagtc ttaatatagg tacagttgca ccagggcaat taataagaat tatcataaag
    18901 ggattagtaa gttcaactgc tacaggagat attactaata cagcagaagt aagtgcagat
    18961 gtaccagaac cagttacgga ttcatcaaca gtgacaactc ctatagttcc atcagcagat
    19021 atagaagtaa taaaaactag caatatggat acaacagttc caggagaaac tttcagttat
    19081 actataacag ttacaaattt aggaccatct gctgcacaaa gtatcgtttt gatagatgat
    19141 ataccagatg ttattttaaa tccagagtat tcattggatg gaggagtaac tttccaacca
    19201 tggaatggaa atcttagtat aggcactttg gatgctggag aaataagaag tattataata
    19261 agaggaacag tgagccagac agcagtaggt acaattataa atacagcaac aataagttca
    19321 actacacctg acccaaatcc agataataat acttcaacag atgaaacaga tataagtcca
    19381 ttagcagata tttctgtgat aaaaggcaac gaaccagttg ctataccagg gggaagattt
    19441 atttatggaa ttgaaattgc aaatgcagga ccatcttttg cagagaacgt aactttaaca
    19501 gataatatac cagcttctat tttaaatcca gagtactcaa tagataatgg agtgactttc
    19561 caaccatgga atggaagcct taatataggt actttagatg ctggagagat aagaaatatc
    19621 ataataaggg gaacagtaag tcaaacagca ataggcacaa ttataaatac agcaacagta
    19681 agttcaacta cacctgaccc aaatctaaat aacaatactt caacatcaga agcagaggta
    19741 agttcatcag cagatatttc tgtagtaaaa cgaagcaatc agactgttgt tgtaccagga
    19801 gatgtactag actatacaat tgaggtgaga aatgcaggac cgtctactgc tcagaacgta
    19861 actttaacag ataatatacc agcttctatt ttaagtccag aatattcaat agataatgga
    19921 gtgacttttc aaccatggac tggaagtctt agtataggca ctttagatgc tggagagata
    19981 agaaatatta taataagggg aatagtaagt caaacagcaa taggtacaat tataaataca
    20041 gcaacagtaa gttcaactac acctgaccca aatccagata ataatacttc aacatcagaa
    20101 atagatataa gttcatcagc agatatttct gtaataaaat tagcaaataa aacagaagca
    20161 tgtgtaggag agcaaataga ttttgtaata gtagtatcaa atgcaggacc agaaaatgct
    20221 caaaatgtta ctttaataga caatgtttca gataagctta agaaagcagt attttcactt
    20281 gatagaggtg taagttttca accatggact ggaagtctta atataggtac actaccagct
    20341 ggaactttaa gagtgattct attaagagga attataaaat caacatgtct tgatagatta
    20401 acaaatattg cagaagttac ttcaacagca ccagattcaa accttaacaa taatatatca
    20461 agagtgcaag tagaaataaa acaatgttgt tgtaatgatt gctgttgtaa caactgtagt
    20521 aattgctgtt gcaatgattg tggttgtaaa gattgttact gtaattgttg taaaaatgac
    20581 ttttggtgtt gattttataa aataattttg tataccttaa attaaactga aataaaaaat
    20641 aaattcacat atgagtaaaa tattttataa atattaataa attttctatc tttgatatgg
    20701 accacattcg taatactagt tattaaatga agtggtcctt tttaattcat taaaattatt
    20761 tattctaatt aaattttaaa tgtattaaat aattttaatt ttttataaaa aatattgata
    20821 tgttatttat attaaagttt agatatctaa aaatactttt agaatttatt atattatgtt
    20881 aattttttat atcttataag gattgtattt ttctaactat aaaaatagta ttatacttat
    20941 atttaaaaat aaaagaattt tattcctatt gtgtaaagtg agaatactat tttcttatat
    21001 tggtataata atagtaaatc taatatagaa aagaggtatt tctagtatgc atgaaaataa
    21061 aaagaatcta ttagacggaa gcttagctca atataatgat acagcagttc caaaaatacc
    21121 agtatttgct ggtaacgata taacttcaga agtttattat tttaaaccta atcaagttct
    21181 taatgctcat agacacccta atggtgaaca aatatttgtg ttcctaaaag gagaaggtaa
    21241 aatgaaactt ggtgagcatg aatgtgatgt aaaaaacgga gatactgtat ttgtaccaac
    21301 aggagagtgg catgaaatta ctaatggaag caatgaagaa atggtagccg ttcaaattac
    21361 aaaaattaat gctggagcag aatacagagg atagatatat aagtacagtt agtactttaa
    21421 tatctatttt attatataaa ctttaatctc aaatataaaa agagtctttt aaaaggctct
    21481 ttttatattt ttgttaattt tcattataaa aaaagaaaat atctagctaa aactaatata
    21541 ttttatttaa tattttttat agcattgttt gcaaactcag tatttacgat atctttataa
    21601 ggtgcttcct tatctagttc tttagcttct ttcataacag tcatcaattt cttcaaacct
    21661 tcctctttta atacaggatt ttgagaccat gcatctattg atttatatct atctacaact
    21721 gttgttaaat cttctaaaga tatatcttca aagaaaggtt gcatagcctt agctacttct
    21781 ttgctagatg cttgttgaat ccataattga cctttataaa cagcatttgt aaatctttga
    21841 attaaatctt tattgttttt catgtatgat ctcgtagtag agtatgctgt aaaaggtatt
    21901 tctccagaat cttttcctat agatgtaact atatatccac taccttcttt ttccattgct
    21961 gttgctgtag gttcaaatgc tgttgtaaag tcaccctctc cacctgcaaa agctccagcc
    22021 attacaccaa attgtacatc agttcttaca ttaacattgc ctacttttag attttctcca
    22081 atagtaagac ctttttcttt tagaacatat tcaaaagtca ttagtggaac tccacctttt
    22141 ctaccaccta atatttcggt tccttttaaa tcattgtaag agaaattagg catttttttc
    22201 ctagcaacta gaaaactacc atctcttttt gtcaattgag caaagttcac tgcataatcg
    22261 tttttgtttt gattatatac atatatagat gcttcaggac ccattaaacc tacgtttgct
    22321 tcacctgaaa tcaaagctgc catagtttta tctgcacctt gggtatttat aaggtcaatc
    22381 tttatacctt catcttcaaa gaatcctttc gtaatagcag catactgtgg agcataaaaa
    22441 acagagtgag taacttctgc tatagttact ttatccagat ttttagacga agaagattca
    22501 ccttttttgt cattagagtt aaaatcacat ccagttagac atattgtact tacaatgata
    22561 gagcttgcta ttgcgactat ttttttaaac ataataaata cctcccataa gacatacgaa
    22621 tagtatatag tattaaaaat ttattgtagt tgttacaaaa atgtatctat gcttataata
    22681 tttctacaaa aacttaataa taattttcag ttttatgttt agttttttta gtaatgtgta
    22741 atattggata aattatattg attatt
//
LOCUS       DAEOTL010000062        22649 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEOTL010000062 DAEOTL010000000
VERSION     DAEOTL010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.062"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            234..1670
                     /locus_tag="KRH82_002725"
     CDS             234..1670
                     /locus_tag="KRH82_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBG8655995.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKGSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIVFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            complement(1762..3636)
                     /gene="asnB"
                     /locus_tag="KRH82_002726"
     CDS             complement(1762..3636)
                     /gene="asnB"
                     /locus_tag="KRH82_002726"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBG8655996.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            3839..4513
                     /locus_tag="KRH82_002727"
     CDS             3839..4513
                     /locus_tag="KRH82_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBG8655997.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            4626..5162
                     /locus_tag="KRH82_002728"
     CDS             4626..5162
                     /locus_tag="KRH82_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBG8655998.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(5328..5948)
                     /locus_tag="KRH82_002729"
     CDS             complement(5328..5948)
                     /locus_tag="KRH82_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBG8655999.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(6262..8400)
                     /gene="vanT"
                     /locus_tag="KRH82_002730"
     CDS             complement(6262..8400)
                     /gene="vanT"
                     /locus_tag="KRH82_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBG8656000.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGVKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(8418..9224)
                     /locus_tag="KRH82_002731"
     CDS             complement(8418..9224)
                     /locus_tag="KRH82_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBG8656001.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(9221..10321)
                     /gene="vanG"
                     /locus_tag="KRH82_002732"
     CDS             complement(9221..10321)
                     /gene="vanG"
                     /locus_tag="KRH82_002732"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBG8656002.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(10582..11664)
                     /locus_tag="KRH82_002733"
     CDS             complement(10582..11664)
                     /locus_tag="KRH82_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8656003.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            complement(11714..12415)
                     /locus_tag="KRH82_002734"
     CDS             complement(11714..12415)
                     /locus_tag="KRH82_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBG8656004.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(12849..15380)
                     /locus_tag="KRH82_002735"
     CDS             complement(12849..15380)
                     /locus_tag="KRH82_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBG8656005.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(15488..16105)
                     /locus_tag="KRH82_002736"
     CDS             complement(15488..16105)
                     /locus_tag="KRH82_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBG8656006.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(16467..17351)
                     /locus_tag="KRH82_002737"
     CDS             complement(16467..17351)
                     /locus_tag="KRH82_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBG8656007.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVKFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(17542..18792)
                     /locus_tag="KRH82_002738"
     CDS             complement(17542..18792)
                     /locus_tag="KRH82_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8656008.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDTKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(19014..19778)
                     /locus_tag="KRH82_002739"
     CDS             complement(19014..19778)
                     /locus_tag="KRH82_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656009.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(19772..20497)
                     /locus_tag="KRH82_002740"
     CDS             complement(19772..20497)
                     /locus_tag="KRH82_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656010.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(20499..20867)
                     /locus_tag="KRH82_002741"
     CDS             complement(20499..20867)
                     /locus_tag="KRH82_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656011.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(21043..22587)
                     /locus_tag="KRH82_002742"
     CDS             complement(21043..22587)
                     /locus_tag="KRH82_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBG8656012.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLIRG"
BASE COUNT         7821 a         3803 c         2362 g         8663 t
ORIGIN      
        1 aagaaaactt gcttgatatt tttaaaatat aattaaaaaa atgtttatat ttcttacttt
       61 ttacatagat tttacatact ttattaaatg tataaaagct atgtttaata tgtaattata
      121 tatcatttat ataaacaagt acatatttta ttttgaaact acaaaattat tgtactatat
      181 tgttttaagt tgttttataa tagattatat catcttatta taggagaaaa aatatgattt
      241 gtactattaa accattaaag atttcaataa aaaagtctac tgaacctcta attgaattta
      301 tatctgatac tacctataaa aataagggtt cttcatatat taaagaagtc tactttacaa
      361 gatatatagg tgttgatgat tcaattgata aatacataga aaaaattaaa aatatagata
      421 cttatttttt taataatcct acaattccct atattagatt aaacaatcta aaaataaatt
      481 ttgacaaaga acaaacagat aagatgctta aaatttttaa tatttatgat agttctaagt
      541 ttaacagttg ggatttatat aatatcgact ttccatgtaa aatagaaaat gacaccttaa
      601 attggactaa aaagattgta tttaaaaata ctttagattt attttccaca agtatgccaa
      661 attgtacatc ctctatcatc aaaaactttg cagttaaact tttgtgttgg atggactatt
      721 ttctacctaa attattttat aacaaggtga agactactat ttcaccaaag atagtatact
      781 ttggaaatat taaaaggcaa gaactttttt tcttatattt tttatcacaa cttgggtgtg
      841 atattttata tataaatcca aataaagata ttcttgattt atatcctgaa tgttcaaaat
      901 tttctactct atttgaactt tctaggaaga ctccaaatat attagaaata ccttttgaaa
      961 ggcatattac aaatataaat tacagtgaaa ataccaataa gacttctcct actacgaata
     1021 aacctaactc taaaaataca cttaataaca caaatctaac atctaaaaaa attgtacaag
     1081 atgaggaagt agaactttct tatgaagacc ttgcaaagtt atcagcttct gttgttatga
     1141 ttgttgtgtg caataacgaa aataaaccgt ttaagagcgg ttctggagta gtaataaata
     1201 atgaaggtta tatacttacg aatcttcatg tagtcaatga tgggtattca tttttagtta
     1261 gatttgaaaa tgatgataaa gtttatacat cttaccaaat tataaaatac cattcagatt
     1321 atgatttagc tgtgataaag gttaatagaa aatgcaagcc aatacctgtt aaagtcagta
     1381 aaaaacctgt gagaggtcaa aaaatagttg caattggaag ccctttaggt ctttttaata
     1441 cagtttcaga tggaattatt tcagcttttc gtgattttga aacggttcaa atgatacaat
     1501 ttacagctcc aatctctagt ggtagttcag gaggagctct tttagatatg tttggaaact
     1561 tactaggatt gatttccgct ggatatgatg atggacaaaa cttaaattta gctgttgaaa
     1621 gtaatcttgt caaaatattt gccaataatt ttattgagat agtaaactaa tcaatcaaag
     1681 ttctacttat cctattccat aataatcagg agggtgaaaa cattgcatgc ttttgccctc
     1741 tgattaatat tgaaaaaagt attaatactc gacattttta tgctcaataa ataattgatg
     1801 ccatagacaa aatgtaaata tagtccatat ttttctcgaa ttatctctat gacctttaag
     1861 atgcgtatct aaaagtttta ttgcatattt tttatctata aattcatcta catttgaatt
     1921 ataaatagtt tcctttacaa tatcccctag agaatctttt aaccaaactc ttattggagt
     1981 tggaaatcct aattttttcc tttgaacaac atgttctggg actatttctc taaacgcctc
     2041 tctaagtaaa acttttgtat tattcttatt tattttttgc tccattctta aattttttgc
     2101 tacatcaaat acatctttat ataaaaatgg tactctaagt tcaacctgct cagctgtaga
     2161 aagtttgcta attttttgaa gtatatcgcc ttgaagccat gtattcacat ctatatgttg
     2221 cattttactt atataatcgt aattattttt ttgtgcatct ctatacaaat tagacaacag
     2281 gtattcatat atattctttt ccttatactt aaaaaagaat ctttttactt cgctgttttc
     2341 aaaaactttt gcatttccta tatatctttt ttctaatggt gttgtagctc tataaagata
     2401 atttcttcct tttatgtttg gcataagttc tgaaactctt cctaatatac ttttaatata
     2461 agtaggtgaa ttgacaactg atttcatagt actatactct ttatatatat tatatcctcc
     2521 aaataattca tctgctcctt ctccagacaa tgctacttta acatgtttac ctgcctcttt
     2581 aattaagaaa taaagaccta cttctgaagg gtctgctata gggtcatcca aagaataaat
     2641 tacattcggt aatgatttta tatattcatc ttgtgttata ttaatctgga tattttctat
     2701 acctaactta tcagctgttt tctttgctac ttctaattca ctatatcctt tgacactaaa
     2761 gcctgcagaa aaagatttta tatttggatt aatttgtgaa gccacagtag ttataataga
     2821 tgaatctatt ccaccagaca aaaatgttcc aatttctttc tcctcttcca tatgagttac
     2881 tattgaatct actactatat ttcttatatc atcctcgttc acatctctat tgcctaagtg
     2941 atttttagta taaaaaaatt ttgtactact tctaaactca agtttattat atctctttaa
     3001 agatagtata ccattttcta ccctaaaata gtgacctgct ggtatcagcc ttattccttg
     3061 tatcatagta tcttcaggaa gtacatattg aaatgaaaaa taactttgta agcttctttc
     3121 atttatattt aaatttttca tatattcaag taaaaactta tactctgagg aaaaaattat
     3181 tgcattttcc ttatttatat aatagagtgg ttttatccca aataaatctc ttgctccaaa
     3241 tatactttca ttttctctat catagattat aaagttgaac attcctttaa tcttatgtac
     3301 acaattctta ccaaattcta tataagatgc caataagact tcaatatcat catttgtagt
     3361 aaaattgtgt ccttttttaa ttaattcttc ttttatttca tgatagttat atatatttcc
     3421 attaaaaaca ataacttttc catctttttc aaatggttta tttccataaa tagcatcaat
     3481 tacattaaat ctttcaaaat caaaagtttt ttcctcatcc ttatactcta ttctactaga
     3541 aagtcttgta ttatttacag attcttttat tttaaattta atatcttctt ttttagatat
     3601 atcaccttta taataaattg aaatattgcc gtccatataa tcaaaattcc tttctgtcct
     3661 ttagtcttat tctatatttc atagttttgt ctttggcttt aaaacttatt caatttaaaa
     3721 tgaaattgct attaaattct tataaattat ctgttaatat ttcatatttt ttttatttct
     3781 agaaatacta tattaggagg tgatttttat gaagaaaaaa atattaatac cagttattat
     3841 gtctttattt ataatctcac agtgcataac ttcatttgct tttacacctg aaaataacaa
     3901 atttaaggtt aaaccattac cttatgcata tgatgcactt gaaccttata tagataaaga
     3961 aacaatgaaa ctgcatcatg ataagcatta tcaagcttat gttgataaat taaatgctgc
     4021 tcttgaaaaa tatcctgagc tttataatta ttctttatgt gaattattgc aaaatttaga
     4081 ttctttacct aaagatattg ctacaactgt aagaaataat gcaggtggag cttataatca
     4141 taaattcttt tttgatataa tgacaccaga aaaaaccata ccttctgaat ctttaaaaga
     4201 agctattgat agagactttg gttcttttga aaaatttaag caagagttcc aaaaatctgc
     4261 tttagatgtc tttggttctg gttgggcttg gcttgtagct actaaagatg ggaaattatc
     4321 tattatgact actccaaatc aggatagccc tgtaagtaaa aacctaactc ctataatagg
     4381 acttgatgtt tgggagcatg cttactattt aaaatatcaa aatagaagaa atgaatacat
     4441 tgacaactgg tttaatgtag taaattggaa tggtgcttta gaaaattaca aaaatttaaa
     4501 atctcaagat taattaaata ttaaaatcct tttgaaaaaa acttatgttt gctatataat
     4561 ataataaaag atagtctaaa tttaccaata taatgtttat agtgacgatt caggaggatt
     4621 tttatatgat aaaagaaaca catgaaaggg gaggttatat attcgcactt ttgatactcc
     4681 cctttataaa caatctatac ctagttaaat acgatattgc atataaaata gtattaatta
     4741 taatttatat ttattttgca tatttaggtt ctttatttcc agatatagat atgagaggtt
     4801 cttacataag taaaaaattt atgttaatat acaaattatt tggaagtagg tttagacata
     4861 gagggtttac tcacagtcta attgccttat tacttattta tagttttttt aaatctctga
     4921 caatcttcac taacaataat atagttttct catgtttgtc cagtgggttt ataataggat
     4981 atctatctca cttgtgtctt gaccttatta ctaaagaagg tattgaattg ttttatccca
     5041 ttaccataaa catttcttta ctacctataa aaactaactc aaaaacagaa aaattcatat
     5101 ctaagctatt aaatttcata gttatttttt tgattggata tcaattttat attttattat
     5161 agttgtagaa aaaataaata acaatatttt gaactaagta taaataagtt ttatatattt
     5221 tagtttacaa aagaactaaa aattttgtac cttaatacaa aaaataaaac gtatcttaaa
     5281 ataatttagt actaaatcat tttaagatac gttttatttc gtacaagcta aatcatttta
     5341 tcatctttat cattgtgatg ttttttatga tggaaatcat aattatgatt ttcaagattt
     5401 ttatttactc tatttccaat cttccatgac aaaaacacca ataatataaa tgatgctatc
     5461 tttaaaggac ttgttataaa accttctata tcacttgcca cgtaacttat aactataaac
     5521 attacaaatt ttcctgccaa cattgctggc acaaaatctt ttaaatcttt tttaccaaaa
     5581 gctgatgcga tagtaactaa acaaccgggc ataaatggac aggcatacgc tataaataat
     5641 aacttaaatc cctgtttatc catccaactt attgcttttt cagttttact atttctcaac
     5701 ttattaaaaa gcttactatc attaaatctg cttattaata agaataatga agttgtccca
     5761 agtcctgagc caatccatga taacaaacat ccaataaata atccttgtat tgcagcattt
     5821 gctgtaacta tagcaacaag tggtaaggct ggtataaagc tttctataaa tgcacttaat
     5881 aagccgatta ttgtggctaa cacccaataa ttttgagtca aatcaagtaa ttcttgtata
     5941 tactgcatat tgcttttccc cttttttaac tttaactatt attatatact ctatatgttt
     6001 attatatacc aatctcaaaa aatgaatcta atattaaaaa gtaaataatc tatataagtt
     6061 tacagttaag gtataattat tttattatat attataacaa aaaaggtgat gtttcaaaat
     6121 aaaaatctga aacatcacct ttttatagct taaattgtca tgtaagttat aaaaaatata
     6181 tattagacat aatattacta aaaatgtcta gtcagattaa aataaattac acagtacaac
     6241 aaatattact atttaattga gttacttctt tataacattt aacctccttc ctactctgct
     6301 caataattca tttgatatac tacatgagtt atttgcaact tcagaagcag ataattcaga
     6361 taaattatct cttcctatta ttattgccgt attaccaact tctacattag gtatatctgt
     6421 aatatcaaca gcaagttggt ccatgcaaat tcgacccact attgctgctc tacaaccatt
     6481 tattattacg taactttttc cacaggataa atttctaggt ataccatcgg catagccaat
     6541 agataatata gcaattacgc tatctctgct tgcaataaag actcttccat atccaaaact
     6601 atcatctttt tgtatttttc taataagaat tacttgtgat tttaaggata aaacaggtcg
     6661 taaatcaagt tgcaatttag tcgtatcatt tggagaactt aatatcccgt ataatgcaat
     6721 tccaattctt acataattac acttaagatt gggataatta aaaaaaccat aactactttg
     6781 aatatgtact ttaggaattt ttacaccttt ttttaacaga aaatcaatta acttataaaa
     6841 acattcaatt tgtttatttg taaagtctac atcttcatct ttcagactat ctgaaacaca
     6901 caagtgtgta aatatgccac atatatctaa gtattttaat ttaaatgcct ttaaaattga
     6961 cctcacatca ttaacatcaa aacccagtct gtgcatacct gtatcaattt taatgtgtga
     7021 ttttatgttg tatttctgtt tgtttaaaga gatagcatga ttaaggtcaa taacactctg
     7081 tgtaagattg tatttatgaa gttcctttgc ccttattggg ttagtatatc caagaatcaa
     7141 tatttctcct agtattccat atcgacgtaa atcaatcccc tcatctattg ttgctactgc
     7201 aaatgctttt acacctattt ggtttgcaca agtcgctact tcaaaagcac tatgaccata
     7261 ggcattagct tttacaactg ccatcaattc acaatcttct ggcatagctt tttgtatcat
     7321 ctttacatta tgttccaaat tatttaaatc aatttcaatc caagctctat tggtatttac
     7381 cttatgttct cctttcaagt ctttttttag aggtttaaga atcaatataa taattataga
     7441 agctataaaa gatgctatac ttaccactat ataatgaata aggctattgt caaccaagac
     7501 agtttgtatt ccgaatattt tagaaaacat acgaataaca acaatcatca taggatgtat
     7561 aatataaata attaatgatg atgttcgcaa taacctagct cgagaacctt tcaaaaatgt
     7621 taaggctgta aataagaaat acatacatgg caataacata atatacatgc tatcatgacg
     7681 ctgtacccct agtttatgta aaaacattcc ctcacataac ataagtaaga atgatataag
     7741 aaatccaatc aagctatttt tagttgacat ataattagat ttattagata ttattccacc
     7801 aagtatgaaa aatacaggtg caaaaaatat gccatttcgt gtataatctg atacttcaaa
     7861 aatataccca tataaattct ttaatagtgg tattttttct aaaaaaccat aataactatc
     7921 accaaacata ccaattacat aaataacaat agtgattact agtgagtact ttaaacctag
     7981 tttttttaca agaaagtatg caatacttgc accaataatt gatgcaggaa gataccataa
     8041 atgatataaa gtcccatcaa atacaatgtc cttaataata ttgggcacta aattattcat
     8101 ggaaaaatat ccagtgtaaa tatttaaggg aatataaatt acaatagcta tcccgtaaat
     8161 aaataataca ttttttagaa aagatttcag tttattacaa ttataattat atgttgaaat
     8221 tagaaaaaag cctgatagca taaaaaagaa tggcacagca atacgagcaa ttatactagt
     8281 taacacaaag tcagccattt tactatatga taataatgga gatgtatgaa ttgcaattat
     8341 aagtaatgca gctataatcc taaaataatc aagccctgca taagatttat tcctaatcat
     8401 tcttgttcct ccatttctta gtcctttcta tttctccaaa atgtcacaat aaaaccatcc
     8461 ttattgttac ccgatatttg atatacacat tgttcaggta tagagattct cacttcttct
     8521 ttagtatgaa taggcacata aaagatttct ataatttttt ctttatcttc tatttttaaa
     8581 caatttgtat acgaaaatct cttaatatat tctatatatt cttcaagagc gagattcatt
     8641 ttattgataa tctcagaatg cggatatccc acataacgaa aatgccatgg ttcttgagat
     8701 attcctgtta tttcttcttt tttacactga taacgctcta taaaaccata atgtagtgct
     8761 gccttacgaa actcattaca aataccatta taaggaaatt cagggcagat aaaatctata
     8821 acttctttct ttaaccctaa atcaatagca agccctgtct gatgttcact gtgatttgga
     8881 agtgctacaa actttttagt aaagtctttt ccattgtcac gcagagaact tgaatatata
     8941 tcttgttgtt cctctgcagt acgatatcca cttacaggta ctatttcatt tattccacat
     9001 atacttttta aaatattttg taaaatgttt gtagcttcac gtttcataag aatacttgga
     9061 aaccttgtat ctacaggaat taaatctata tcttcagatg ttttaactgg taaaaaagca
     9121 tttactagaa ttagattccc atcataaact ttatctttag tcaataagat agtatttgtc
     9181 attttatctt ctttattttt atctaataaa atattattca tcattttatg tacacctcaa
     9241 ttatcttgtc caatatttct tcaaaagaca gtccaatacc tttcatcata tttggataac
     9301 gactatgaga agtaaagcca ggaattgtat tgacttcatt aaaaataatt tcaccagatg
     9361 gagttaaaaa catatctact ctagcaaatc cagaacatcc aagagttcta taaataattt
     9421 ttgctgtctc ttgtattctt ttctcacaat ccaaatcaat tctagctggc atatgaattt
     9481 ttgaactttt caatgtatat ttttctgtat aatcaaaaaa tccttttgac aattctattt
     9541 catctactct tccaacaagt aagtcattgt ttcctaaaac tgcacaccct acctcaaaac
     9601 catcaatatt ttcctcaatt attacttcat tatcatgttc aaaagccaag tctactgcta
     9661 cttgtaactc ttctttttta taaattttac taataccaaa tgatgaacct gcacgcacag
     9721 gttttataaa taatggataa gttaagtctt ttgacagttc agccacatta aatttatctg
     9781 agtattttag taatattgat tttggtactt taataccttc tgaatgaaca agtttatgtg
     9841 atttgtcttt gtccatacat aatgctgaag aaagagtacc acatccaata acctgtatac
     9901 ctgccaattc aaataacccc tgcactgttc catcttctcc attttttcca tgcaatacag
     9961 gaaacacaaa atcaagttta gtgtatttaa tatcattttc acatgattca atagcactat
    10021 ttggaatatg attctgagaa acagcatcag gaattaaaaa ttcaataata ccatttttga
    10081 cacggttctg cgaaacaata actggaatta tatcagtatc cctttcaaac caagtgttat
    10141 tctggatatt attataatct ccaatataat gataccaatt accctccctt gtaattccaa
    10201 ttggtataat atcatatttt tccgtattca aattctcaag tactgcaaaa gctgattgta
    10261 atgatacatc atattctgtt gagtttccac caaatataac tgcaattttt ttattattca
    10321 tctttgattc tcctttgttg atttatttat ttttatacaa tctacagaaa catgttaaaa
    10381 tactttttct atttcaaatc caatcaacct tcacttacaa ttgcatctgt tccacataat
    10441 atattttcac atttttctat tgatataatt actgtatcaa aataaaagca ctcttgtttt
    10501 gatacagtaa ttatatcaat aacaagagtg ctctttattt atttatccta aagaatttcc
    10561 tattttttta tacttaaatt cttacaaatt tcctacaatc ggaataataa ccttaaaggt
    10621 aattatattg ttctcgctat gagctgttat tgtcccgtta tgaagctcca ctatttcttt
    10681 agctatagca agtcccaacc cagctctacc actgtttgaa ttacgagatg tatccaacct
    10741 gtaaaattgt tcaaaaatac gctcaagttt ttcctctgga atcgtattgc tatgattcat
    10801 aaatttaagc tttatataat catcctcctg tacagctgtt atttcaatag tagtatcttc
    10861 aaaactataa taaacagcat ttcgtaataa gttatcaaat acacgttgca ttttattaac
    10921 atcacacctt atcatcatat ttggtgtaac attcagtgta tattttaaat tcttactcat
    10981 caaagtaggt ttaaactcat atgttagttg ttcaagcata cgagttaagc ttactgtact
    11041 gtattcaagt gatatatttg ataaattaaa ccttgtaatt tcaaagaatt cattaattaa
    11101 atcttcaaga cgctctgcct tatccaacga aatagataaa tatttttttc gcagttcttc
    11161 agaaatctga ctttcatctc gaagtagtgt cagataccct ataactgatg taagtggtgt
    11221 ttttaaatca tgtgcaagat aaacaataag ttcattctta cgttgttctg ccatttgtgt
    11281 ctcaaattta cgttgttcaa gtatatgttt aattgagttt attttctttt ctattgccaa
    11341 taactctgga gataaagcca cttctccaac atcttctttg ataagagagt caataccttg
    11401 atttatttca ctaaaatatt ttgtaaacca atttaaataa acacggaata ttataaaaaa
    11461 cacaatcacc atagctagta tcatgaagag ctccatgcta ttacggaaaa tctgctgata
    11521 taaattcaat gcagctttat attccatacg aaaagcattt tcaaaaaatg atactatcca
    11581 gatagaaaac ttaccataca atataaaaga atataaaatc catatgaaaa taatggctat
    11641 aaatgccatt aaagctgttc tcataaaaat tttatttctc acttgagtaa agtcaggatt
    11701 gactttaata tttttacttt tcaattgtat aacctactcc ccatacagtt tttataaatt
    11761 tcgggttttt agaaggttca tgaatttttt cacgtaatcg ccctatatga gccataactg
    11821 tgttattatt atcaagatat ttttctcccc atacagcttc aaacaattct tcagaaggaa
    11881 ccacttttcc ttgatgttca cataaatacc aaagaataga aaattcaatc ggtgttaatg
    11941 ctacttcttt cccaaataaa ctacatttat gtgtttcttt attgataatc aatcctttaa
    12001 tatcatactc attaacaatt atcgactgtt gttcataaga attattatat cgcatatatc
    12061 ttcttaattg tgtctttact cttgcaacaa cttccaaagg gttaaatggc tttgttatat
    12121 aatcatcagc acctatggtt aaacccatta tcttgtctat atcttcaatt ttagctgtta
    12181 acataatgat aggataatag tatttttctc gaattttctg gcaaatatga aatccatcaa
    12241 tatcaggaag cataatatct aaaatagcca tatccaaatt tttagattca atacattcta
    12301 gagcttcctt acctgtataa aacttgtata ctgtaaaacc ttcatttttt aaatatactt
    12361 caattaaatc tgctatttct ttttcatcat ccacaatcaa aatattttcg ttcatagatt
    12421 atttttcact ctccttatta tcgaggtcat catttataat attggtaaat ttacatatca
    12481 aataattaca agcatatttg taactaattt ttataagaaa agaactacta catcagaatg
    12541 tgttgatgct accattggaa cacaaaaact gagattaatt gttattataa aaactcccct
    12601 aacacgtcct tattatcgca taacaggtat taactttcaa taaaaatatc tatcagtcaa
    12661 acacaattca atttattata ccagagacaa tccatataaa aaataattaa acctatgtat
    12721 gtaaccacag acattactaa aatttccatg ttattttata taaaaattca aaaaaggagt
    12781 tgaatttaaa atttgattag aaaaaaatca attttgagac aactcctttt tattttaatg
    12841 tatttaaatt atagtatatc agccttcata atatcctcaa aatcaccttt ttcagatatt
    12901 aatcttatca atttaacagt acagcttaaa tcatttataa gtatagctcc aactaatgaa
    12961 ccatctttca taaataattt tttatatatt ctttgacctt catcttttga tgaaatttct
    13021 ttatcaaaat tttgtatatt accaatacta aatactttta cattcattgc atctaatgaa
    13081 actggatata cttcactttc aaatgtcaaa ttatctccac ttgcatttgc ccctgctatt
    13141 tttcccattt ctactgaaga tggccatatt gctaaactaa tatttcccac ttgtgcaaca
    13201 tctccacaag catatatatc tttaatattt gtctgtaatg tcttatctac aacaatacct
    13261 ctatcaattt ttacagatgt atcctgaacc atttgagtgt ttgctcttac accaattgaa
    13321 aatactacca tatcacagtc aacactatct ccatctttaa atacaacttt ttgagctttt
    13381 ccatcacctt caataccatc aactgctaca cccaatctta catctattcc tgtatctctt
    13441 acacattgtt ctaatatttt actaccttct ttatcaagtt gttttgatag tatgctatcc
    13501 atggcttcaa ctactactac ttctaatcct tttagtctaa attcccatgc agcttcaagt
    13561 cccaataaac cgccaccaat cactacaact ttcttagatt tttctagtgc ttcttttaca
    13621 ctatataaat cttttatatt tctaagagta aacacatttt ctaaatcatg acccttaatt
    13681 ggtggtataa agtttctact tcctgtagct attacaagct tatcaaattt aatagctcca
    13741 tcattcacta taatagtttt attcacttca tctaatttat ctacattcgt tcctaatatt
    13801 actactatat tatttttatc ataccaatct ttatcttcca tgtagaaatc tgaaccaagt
    13861 tcttcattta taccatcaga aagtgcaggt ctatagtaag tcaactcatc ttcattagaa
    13921 atcatagtta tcttacaagt tttatttctt tttcttatag catctgctgc ataaaaacca
    13981 gctgctccat ttcctactat tacgaaatat tcatcagtat cttttctaaa agtaacttca
    14041 tcttcttcaa cttctataaa ttggtcttcc ttagctccac atacagggca tacactagga
    14101 gcactatcac cttcaaaaac ttcattacaa attacacatt taaatttctt agttttcttt
    14161 ttacttccaa aagtagaatt taacttatct aggaatttac ctgtataaga atgtaattta
    14221 tcaatctctt catttgatgg tttaaagtta acagcaaaag gttttactgc tgtcattcta
    14281 agctgactta ttctctccat agcattttct ataccttctc cactccatcc atatgaacca
    14341 aatactgaag caacttttcc accatgaaga actgggttta acgatattaa tatatcccat
    14401 ataggcttta acgcatctcc taatattgtt ggtgttccaa ataatacacc ttgtgatact
    14461 gctatttttg ccaaaatatc ttcttgctta tgctctatta catcaaataa atttacttta
    14521 tagttgctat ttttttcaat atatgctttt atagcttctg ccataatctt tgtatatcca
    14581 tgtgcagaaa cataacaaat tgtaacttct ttttctaact ttatttgttc atttacactc
    14641 cagttgtaat aaaggtctat aatttttcta ggattttcag ttaatactgg accatgacct
    14701 ggacatacag tatctatatc taaatctttt atcttttcta tagcagttac catagatggt
    14761 ttaaatggac ccattataca atcataatag tatcttaaag catccaagta atccttttct
    14821 tcattttcat caagtgtatt tactatctta tcattactat agtgactacc aaatgaatca
    14881 catgttacaa gagttttatc ctcttttata tatgtgtata tggtatctgg ccaatgaagc
    14941 ataggtacag agaaaaattc taaagttttg tccccaattg ataatgtatc tccatctgta
    15001 actgcaacat attcaaagtc tttgtttacg atttccttaa gatatttaat tgctgtttct
    15061 gaagctacta cttttgcatt tttagctaaa tccaaaagct tttcaacgct tcctgcatgg
    15121 tctggttcag tatgacttac aacaatatag tctatttttt caaaatctat atttaaatca
    15181 tttaatcttt caatataatt gtcaaaatgc ttatctttaa ctgtctcaaa taaaactgtt
    15241 ttttctgttc cttttaatac atatgaatta taagtagttc cataaggtgt atacataatt
    15301 atgtcaaata ctcttaaatc agggtcaagc gaacctaccc aatataaatt ttcttttatt
    15361 tttagtgatt tcaatgacat accgtactcc tcctaaaata gttatttagt ctctttatac
    15421 cctgcttgtt atattttaaa caaaatttat tcaaaaaaga aattatttta aagatagttt
    15481 aaatcttcta atcttctttt tctaccttca atacagttcc ctttttagaa tctactttta
    15541 tgtcatattc atttttatct ttatctattc ttattttata aaaagtaaca tctaaatctt
    15601 tgtctaaact ccattcttta actattccat tttgttcttt taatgcaatt tccatagctt
    15661 gttgaggtgt cattatgtca tttaaatcta atttttcttt tctagcaact ccatttaaat
    15721 cttctgaatc caacttttct gttttatctt ctaatacatc ttttgtatta gcatcaattt
    15781 tcatcttata ttcattatta tcatctacac cttccacagt ataaacaaat ttatttaaat
    15841 ctctctcaag acttaaatct actatatcag catccttata tttatcttta aatatgttta
    15901 ttgcatctgt gtatggcact ttaaaatctt gttccattaa attttcatta tttttttcat
    15961 cttttaaagc gttatttgat gcatttgcct ccttttttgt attatcttgt gcttgtcctg
    16021 aatccttagt tggactccca ctacatgcag ttaataaacc cgctataagc atacttacca
    16081 ctaataaata cgttttttta cacataaaaa ccctccttaa atatattaat ttattctata
    16141 ttatgccctc taaacccttt atttaccctt ttatattaaa aattcctcct attttatcaa
    16201 ttttaaaact ttatatttac taaaattaaa gttacataaa aattatactg tctcaaaatg
    16261 gaaacaagcc tctttttcat tgttgaaata ataaaaatat attttatttc gtacaaaaag
    16321 agtgcctcat gaactaaaaa gttcattttg agacactccc atttttttat atttttactt
    16381 acaaaataac agtacttatt aattttttac aaaccttata agtatatcta tatgatattc
    16441 ttaaatttaa acactatatt aaaaaattaa attttgttta attcttttac cgttaaatcc
    16501 attttaggat atggaatcgt aattccttct tcgtcaaact taactttaac ctcttctagt
    16561 aaatcaagat aaattgtcca ataatcttct gtcttgcacc aaactctagt tgcaaattta
    16621 atagcattat ctccatgttc tactactcct ataaatggtt ctggttcatt tattattaat
    16681 ttatgattat taacaatatc tttaagtact cttctaacat gtagtatatc atcttcatac
    16741 cctacactaa aagtcaaatc aactcgtcta gtattctttg ctgaatagtt tattagacta
    16801 tcatttgata cagaaccatt aggtataagt atctgtttat tatctggagt aaccaattgt
    16861 gtataaaaaa gacctatttg ttcaaccgtt cctccatgac ctgctgcttc tacgtaatct
    16921 cctactttaa aaggtctaat caatagtata ataaatcctc cagcaaaatt tgatagacta
    16981 ccttgtaaag ccaaacctat tgctacccct gctgatgcta tcacagcagc aaaactggac
    17041 aaactcattc cccaatattc cagaacaatg attataacgg caactttaag tacactcaaa
    17101 agaagagact ttaaaaactt tcttaaagtt aaatcaatat ctcttttact aagtaataac
    17161 ataacatggt ttacaaattt ttttattatt ttaaatccaa tagaaagtat aagtatgcct
    17221 attataagtt ttactccgct tgtagtagcc cattctagca gactttccat tatacctccc
    17281 atatccatct tattaatatc taaattattt aaatctaact tgcttatatc atctattttc
    17341 gtcgtatcca taaaaaactc cttaccttat attttagaac caatattata gtttaaagtt
    17401 cttattttct atttaatata atacaatacc atttgtacat agtaaacaag atttatattc
    17461 caattataca tattaggaaa atgcaaacta tttgttatat atatgcaaaa tataatacta
    17521 aattaaacta ttaataaaac actatatagc cttaaaatca tcatttttta cccctatatg
    17581 agatgatact atagttataa tacttagtac tataaatact acaaaacctt ttttatatcc
    17641 atcaactata ttatatgaat ttacttgtaa agagatagct ataatcaaat taataattcc
    17701 acttcctata aattcaaaag tattaataac actagttgcc agtccagaat aaatttcttt
    17761 atttttatac ttggtatcat taaaaacctg tagatgtgac ataactatac atcccataat
    17821 aaagaatgat attggtaaaa ctataattgg tggttttacc tggtatacaa ctacaattac
    17881 aatccatata aacaaatcta tcattgctcc aaattttatt atattaaatt tgctagacct
    17941 tattttagca aatacaaaat ccataattat tgaaccaaat ataaatccat atgtaaaaaa
    18001 tgatactata aacgcagaaa aactcttact cacaccataa acgtccatta tgtatcttac
    18061 tccccacaag cttataaatg cacttgtaag accaacaaaa gagaacatta tcattgaatt
    18121 ataccatgtt gatttgttct ttataacaga cttaatacca tcaacaatat taaccttctc
    18181 tgacttttca tagggttcag tatctacatt gaatccatac tcttttggtg tatctctaac
    18241 aataatatac ataaaacatc caattacaac accaattata ccgattaata aaaatgaatt
    18301 tctccaacca acaagttcag acaaaaacac aagtggaaaa gtagcaagaa ctccacctaa
    18361 atttcctaca aatgaaaatt tagctgttgc agaagcaaat tctgacttat taaaccatct
    18421 cccttgaatt tttaaaatac aaagtaatat tactgatgtt cctgccccta caattacacg
    18481 agaaatatat gctaattcta tactttgaat caaaccaaat aaaattgacc ctaaacttgc
    18541 cattattatt ccaagactgc taatttttct tgctccatat ttatcaatca aaattcctgc
    18601 aggtatttgc ataaatgcat atgcatatag gcaaaaggat gctatatttg aaatttgtat
    18661 agaattaaaa cctaactcat ttgctaaatt gtctgaaaca acagcagttg acatccttaa
    18721 aaataatact aaaacaaatg aaaatgtaat tataccccaa acactccact tagcctttgt
    18781 ataacttttc atatcttctc cctcaaatcc atatattttt aaattttctt gatataactt
    18841 atataaagtg tatagttatt cttacaaatt tttacacgca atatcattat acaacatatg
    18901 tatatattta actagaaata aaacactatt catattatat acatgaatta actacataaa
    18961 taataagagc catcttttaa cattactcaa aagatagctc catataaaaa catttattct
    19021 aaatttaatt ttttatctaa tataaatttt gtagcgaaaa ataacgctat tgcaactaca
    19081 agactaccaa gtattgcaag cataaaacta ggactctgat aaagatgata taccatattt
    19141 gtatcttcat ttggtaagat gcttccaact gcatctccaa caattgatat tactatattt
    19201 atagctataa aagaagcaaa tgccactatg tttctatgtt tattgaattt tggcaattgt
    19261 cccattgaga ttgatgtata taataacaaa ataaatgatg aatatgaaat aaacattact
    19321 actactaata ataaaatatc taaaaagttt tcagaaatcc atttaaaact agtgttaaac
    19381 aaatctaaaa tttcaggtag taaaattcca gaagtaccaa aaagcataag aactccaaaa
    19441 gtgaatactg caactataaa actaagtaca gcgtatataa gtgctgttat acatttagat
    19501 aatataagtg aactagtgct aacaggaaga gtaaacatta aataaccttc atcccccaaa
    19561 agattttttc taaacctttg aattgtaact acaatagtta aaactcctaa tgccataaaa
    19621 agacttgtta atactagtat tcctattccc tgtacctgaa gtatatttgt attcataaat
    19681 attccattaa atacagctac tatcaatatg gctatatata acggtataaa tattcttcca
    19741 cttgctttta actcatattt taataattta cctaacattt aaattcctcc ctaaataatg
    19801 catctataga ttttcctttt tcttctctta ttgcttcaac gtctccttgt aacactattt
    19861 ctccttttga tatgaatatt atctcatcac atatgttttc tatttcactt attaagtggg
    19921 tagcaatcag taaagtacta tcttcagaat aattttttaa tatagtctta agtatatatg
    19981 accttgcagc tgggtcaaca ccacctatag gttcatccaa tatatatatg ctcgcatttc
    20041 ttgacattac taaaataagt tgaacttttt ctttagttcc tttagacatt gtctttagct
    20101 tttcatttac atcaatatct aagcttttaa tcatctcatt tgctcttcta acatcaaaat
    20161 cactataaaa atcatagaaa aacttaagta aatctgatac cttcatccaa tcatttaaat
    20221 aagttctttc tggtaaatat gaaactattt ttttagtatc tatggatggt ttcattccat
    20281 ttatcataat ttcaccatta tcaggctgta ataatccatt cattagctta atcattgtac
    20341 ttttgccact tccattaggt cctaacagcc cgactatttt tccctttggt atatttaaat
    20401 caatattttt taaaacattc ttagttccat aactcttgtt tacaccttta aattcaacta
    20461 ttccatcttg agaaacattg cttatatttt tatccatttt ataattctcc tttcagattt
    20521 tctgtaataa gttttagcat ttcatctcta tcatatccaa gcttttctaa ggttactttt
    20581 aatgtattta tctccacatt agctatttcc tctttcatag cttttatttt ttccttatca
    20641 tctgttacaa atcttccttt agttctctga ctataaacta aaccttgtct ttcaagttct
    20701 gttagagcct tttgcattgt atttggatta acttccgcat cttctgctag tgctctcact
    20761 gtttctaatt tagatcctat tttaatttcc cctgaaatta tttttaactt taaatgttct
    20821 actaattgta tatatatagg tttgttatta tcaagttccc attccatgtt catgcctcct
    20881 tattatatta ttgtattaag ttgttaatac aataatataa taatacaaag tatatgtcaa
    20941 ttacttttta gtaaaagtat aaaaaatttt acaaaaaaaa tgaacactac attagagtcc
    21001 atttttaaca caatttatta aattctttat attacagatt aattaccctc ttatcaagtt
    21061 ggatacaatt aaatgttcaa attcttcaat tggcattggc tttccaaaca aatatccttg
    21121 tgccatatca cactttactt cttttaaaag tttaaactgt tcttctgtct caactccttc
    21181 tgatatgact ttcataccca actcttttgc catttctatt actttagtaa caattatttt
    21241 gcttctttta ctattataag tttccataat aaatttttgg tcaagtttta agatatccat
    21301 aggaatttct tttaacatat ttaatgatga gtaccctgaa ccaaaatcat ccatagatat
    21361 taaaaatcct atttttttta aattattcat tatatcaatt aaaatatcaa aattatcaaa
    21421 tatgatactc tccgttaatt caagttctat atactttgca ggtatattgt atttatcaat
    21481 tatatttttg tatgtttcta taaaattatt gcaatataaa tgtatccttg aaacattaac
    21541 tgaaacagta actggattta ttcctgcatc aatccatttt ctaaggtata tacatacttc
    21601 ttcaagcaca tataaatcta aatttataac aaaaccgttt ctttcaaaaa atgggataaa
    21661 ttcatttgga ggtattagcc ctttatcagg acgtttccac ctaacaagtg cttctgaacc
    21721 ttgtatctct cctgtattaa gttctatctt aggttgtaag tatataataa attctttatt
    21781 ttctagactt gaaaacattg tattttccat ctctttttct tttatctctt ggtcatgaat
    21841 cttattatca taaaatgcat atgaactttt atgtcctccc tttgccattt tatgaggtat
    21901 attagcccta tctatgattg agttgatatc tctatcttct ggaagtataa aatagattcc
    21961 acaacttaaa actaacttat atttttcttc ttgattatta ttaaacaagt ctaattcttc
    22021 aaatatagtt tttaacctct ttgttatatc ttcttcttct atatatttca taattataat
    22081 aaaattatcc gcagatattc ttgcaaacat ttcctcttca aatatattac tcttaataat
    22141 ctttgttaaa ttacgcaaaa tttcattccc aacttcatat ccaaataaat catttatata
    22201 tttaaattta tcaatatcta tatataataa agcatacttt acttgagtat ttttacatag
    22261 tattttgtta gcatcaatta caaatttatc tatagtattt gctcctgtaa gattatctgt
    22321 atatgctatc ctttgcaatt taattttaaa atttaattta tcatatatta tatagaatat
    22381 aagtattaca catattatag ccataataag tattatttgt attgcatgtt tgctaataag
    22441 ctgattatta gacacaatag actcaaagtt atttatggag ttgtttttat agagtttgca
    22501 taaagaatag actggtgttg tgtatgtaat ttgtaaaatt atacaaataa ataaaaaaaa
    22561 catcaatttt ttttgtaaat tcctcataaa aatttcctcc cattaaaaca cctctatttt
    22621 attagcaaat aagtacatct caaaagttt
//
LOCUS       DAEOTL010000063        22616 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEOTL010000063 DAEOTL010000000
VERSION     DAEOTL010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22616
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.063"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(442..2829)
                     /gene="cadA"
                     /locus_tag="KRH82_002743"
     CDS             complement(442..2829)
                     /gene="cadA"
                     /locus_tag="KRH82_002743"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBG8656013.1"
                     /translation="MEANNLIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENASSKISIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEADDVINKIKEIINSTEPGLD
                     IQVESTNKVKGRTTEKPGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGISMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKAIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2852..3217)
                     /locus_tag="KRH82_002744"
     CDS             complement(2852..3217)
                     /locus_tag="KRH82_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656014.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3417..4250
                     /locus_tag="KRH82_002745"
     CDS             3417..4250
                     /locus_tag="KRH82_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656015.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNMNSNMGIPN
                     NMSNNMNSNMGMPNNMSGNMNNMYGNTSMPNNMNSNMGYNMNNTMSIPNFSCNQNMPP
                     NVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSIQGIPQTTNIEEFDEEE
                     M"
     gene            complement(4398..5486)
                     /locus_tag="KRH82_002746"
     CDS             complement(4398..5486)
                     /locus_tag="KRH82_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656016.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFARVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5611..6339
                     /locus_tag="KRH82_002747"
     CDS             5611..6339
                     /locus_tag="KRH82_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBG8656017.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6540..7031)
                     /locus_tag="KRH82_002748"
     CDS             complement(6540..7031)
                     /locus_tag="KRH82_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656018.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7042..7485)
                     /locus_tag="KRH82_002749"
     CDS             complement(7042..7485)
                     /locus_tag="KRH82_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656019.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7475..8314)
                     /locus_tag="KRH82_002750"
     CDS             complement(7475..8314)
                     /locus_tag="KRH82_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656020.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            9084..9530
                     /locus_tag="KRH82_002751"
     CDS             9084..9530
                     /locus_tag="KRH82_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002599264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656021.1"
                     /translation="MIKFEKLNIINNKDMKEILDTWESSVRATHDFLSEEKIISIKPQ
                     VKEGAKYVSNFLCVRDKKGLIKAFMGIHDFKIEMLFVGNYSIGNGIGKRLAEYAIEVL
                     NVNYVDVNEQNQQALGFYKHMGFKVFKKSEFDEQGNPFPILHMKLK"
     gene            complement(9760..9900)
                     /locus_tag="KRH82_002752"
     CDS             complement(9760..9900)
                     /locus_tag="KRH82_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656022.1"
                     /translation="MKNENISYLALGLCFGVILGSLFKNLAIGLSFGLVIGVVLDSKK
                     NK"
     gene            complement(10461..11846)
                     /locus_tag="KRH82_002753"
     CDS             complement(10461..11846)
                     /locus_tag="KRH82_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656023.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKY
                     TVGSFEYTPII"
     gene            complement(12019..12762)
                     /locus_tag="KRH82_002754"
     CDS             complement(12019..12762)
                     /locus_tag="KRH82_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBG8656024.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(12782..14044)
                     /locus_tag="KRH82_002755"
     CDS             complement(12782..14044)
                     /locus_tag="KRH82_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656025.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEISEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKGLEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(14228..15226)
                     /locus_tag="KRH82_002756"
     CDS             complement(14228..15226)
                     /locus_tag="KRH82_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBG8656026.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWGGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(15210..16721)
                     /locus_tag="KRH82_002757"
     CDS             complement(15210..16721)
                     /locus_tag="KRH82_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBG8656027.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVESLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKDILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(16775..17737)
                     /locus_tag="KRH82_002758"
     CDS             complement(16775..17737)
                     /locus_tag="KRH82_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBG8656028.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(17785..18675)
                     /gene="rbsK"
                     /locus_tag="KRH82_002759"
     CDS             complement(17785..18675)
                     /gene="rbsK"
                     /locus_tag="KRH82_002759"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBG8656029.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIKVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(18717..19730)
                     /locus_tag="KRH82_002760"
     CDS             complement(18717..19730)
                     /locus_tag="KRH82_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBG8656030.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(19959..20936)
                     /gene="bioB"
                     /locus_tag="KRH82_002761"
     CDS             complement(19959..20936)
                     /gene="bioB"
                     /locus_tag="KRH82_002761"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBG8656031.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(21142..21405)
                     /locus_tag="KRH82_002762"
     CDS             complement(21142..21405)
                     /locus_tag="KRH82_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656032.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(21475..22548)
                     /locus_tag="KRH82_002763"
     CDS             complement(21475..22548)
                     /locus_tag="KRH82_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBG8656033.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
BASE COUNT         7340 a         4049 c         2271 g         8956 t
ORIGIN      
        1 cttaaaaata attcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagttatac tgttgtttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa atcttctata tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatgtgtaat
      301 gaatatagat ttatatatac aaaaacgctc caataaaaag gtaccaataa agttaaaaga
      361 aacttattga taccttttat tattatatac ttcaatatat aattataagt tttttgaata
      421 gtatggattt acatttatcc cttatctcat agctctcata gcatttacta ctgctataag
      481 tgccacacct acatcagcaa atatagcttc ccacatagta gctactcctc cagcacctag
      541 tatcataact ataattttta ctcctagagc aaatattatg ttttgccaca ctatcttatt
      601 agtcttgttt gctatttcaa ttgctttaga tatcttgcta ggctcatctg tcataagcac
      661 tacatctgca gcttcaatag cagcatctga acctaagcct cccatagcta taccaacatc
      721 agcacgagct aatactggag catcatttat tccatcacct acaaatgcta ttttctcttt
      781 ttcagttctt ccttcatata aatcttctaa tctatctacc ttttcattag gaagtaaatt
      841 tgagtaaact gtatccaatt ctaattcttg agcaatattt tttgctactt tctcattatc
      901 tccagttaac attacaactt cttttacccc tattgctttt aagcttctta tggcattttt
      961 actatcttct tttacttcat cagatataac tatataacct ctatatactt tatcaacagc
     1021 aatatagact actgtaccta cttctttagc tgatgaataa gatatatttt cttttttcat
     1081 aagtttctca ttacctgcta atataaaatt gccattatgc tttactctaa ttccataagc
     1141 tgctatttcc tcataactgt ctattgtatc taaatcaatt tttttattat agtaacttaa
     1201 tatagacttt gctattggat gatttgaatt tacctccgca atagctgcat attctaataa
     1261 ttcttcttct gatatacctt caggatttaa cttagttaca ttaaacacac ctttagtaag
     1321 tgttcctgtt ttatcaaata ctactgtatc tacacttctt aaagcttcta aatagttact
     1381 tcctttaata aggataccat ttttagatgc aaacccaatt ccactaaaga aactaagtgg
     1441 tattgataaa actaatgcac aagggcaaga aacgactaag aatatcaatc ctctatataa
     1501 ccaatcacta aatacctcac ctgagattac aagtggtggc acaaatgcta ttaataaagc
     1561 agctattact actatcggag tatagtatct tgaaaactta gatataaagt tttctgtctt
     1621 tgacttttta atgctagaat tttcaacaag gtcaagaatc ttagaaactg ttgattctcc
     1681 aaaactcttt gtaacttcaa tactcaataa agcattttta tttataacac ctgataaaat
     1741 ttcgtctcct ttttcaactt ctctcagtac tgactctcct gtaagtgcag aagtatctag
     1801 catagaaatt ccatccacta ctacaccatc taatggtact ttctcaccag gttttactac
     1861 tattatatcg cctacattta cttcttctgg tgacaccacc ttaacttcag aattaacttt
     1921 taaatttgca tagtctggtc ttatttgcat aagtgaagtt atagactttc ttgatttccc
     1981 aactgcaaca ccttgtaaat actctcctac tttatagaaa agcataaccc ctactgcttc
     2041 tgataactcc cctattgcta atgctcctac tgttgctaga gccatcaaaa agttctcatc
     2101 aaatactctt ccttttgata tatttcttat tgctcttaaa agcacatcgc cacctactat
     2161 tacataggca actataaata ctatattgct aaactgactt tcataacctg tagctgtttg
     2221 atatatacca aatatatata caagtgctcc aattataagt ggaattaatt ctttcttatt
     2281 tgtatcattt acagctcctg gtttttcagt agttctccct tttactttgt tagtagactc
     2341 tacttgtata tcaagccctg gctctgttga atttattatt tcttttattt tatttataac
     2401 atcatccgct tcaaagttat tacttatatt tactgtaagt tttttattta caaagtttaa
     2461 attagaagat tcaacttcct ttaatttaga aactttgtta ttaatttcct ctgcacaatg
     2521 tgcacagttt aatcctccta atataagctc ttttttaatt gatattttac tagatgcatt
     2581 ttctttagaa cttatttgta tatcaagacc tggttctgtt gaatctatta tatctattat
     2641 cttttctata gtagtatcct cattaaagct ttcctttata tttactgtaa gttttttatt
     2701 tataaaattt aaattagaag atttaacttc ttgtagttta gaaactttat tattaatttc
     2761 ttctgcacag tgagcacaat ttaatcctcc taggataaat tcttttttaa ttaaattatt
     2821 tgcttccata tatattcact cctctcattt atcatttata agtctctcta atatgattta
     2881 atccacaatc aaatatctga cttatatgac tatcatctaa tgagtaatac actgtttttc
     2941 cttctcttct aaactttact aatctagcct gctttaatac tctaagttga tgagatattg
     3001 cagagtgagt catatttaat aaactcgcta tatcacatac acacatttca tttgcaaata
     3061 atgcatataa tatctttact ctagtagtat ccccaaatac tttaaataat tctgctaaat
     3121 catataacat ctcttcatct ggcatagttg atttagcctc tgttactatt tcttcatgta
     3181 ctatattaca attacaatca tttatctctt ctctcatttt taatcctcca attattttaa
     3241 tatatgaata actgttcata tgttcattat atgctatcat ttctaaattt gcaacaataa
     3301 tttttattaa tttaatataa ttagaatgca catattataa acttttttaa tatatatatt
     3361 attagaataa gtttttgtaa acttttttat agttttctag gaggtgcaag tttaatatga
     3421 gtaacaagaa aaaaaaggat ttagatacta gttacatgcc ttacttagac ccagcgaact
     3481 atgcagatta tattactaat gaagaaattc ctcaagatga attgagaaat gaccctcaaa
     3541 tttctaatgg ttatacaaaa atacctaata accagaacat aaataaccta tatcctaata
     3601 atgtaaatca ttatcctaaa agtagtaatt ctccaaacaa cttgcctaac acaaataata
     3661 catccggaaa tatgaattac aatacgtctg ctacaaataa tatgcctaat aacatgaata
     3721 ataatacggg tatgcctaat aatatgtcta acaatatgaa tagtaatatg ggtatgccta
     3781 acaatatgcc taataacatg aatagtaaca tgggtatgcc taacaatatg cctaataata
     3841 tgaatagtaa catgggtatg cctaataaca tgaatagtaa tatgggtata cctaacaata
     3901 tgtctaataa tatgaatagt aatatgggta tgcctaacaa tatgtctggt aatatgaata
     3961 atatgtatgg taatacaagt atgcctaata acatgaacag taatatgggg tataatatga
     4021 acaatactat gagtattcct aacttctcat gtaatcaaaa tatgcctcct aatgtactta
     4081 tgatgatacc aggagttata tgtcataata caatgcaagg tatgcctgta gttatgccta
     4141 gtactatgcc tcctaatata tatcctactc cttatggttc tagtaatatg tctatacaag
     4201 gtataccaca gactactaat attgaagaat ttgatgagga agaaatgtaa tatatatttt
     4261 tttaagtaag ttgtataaaa cattaataat tgaccataat aataaatgta ttcctcataa
     4321 tattccccca atattataga aataaattta agcgagatta aattcagtta atctcgctta
     4381 aataatgtct aaatttatta ttccaaaaaa tcatcaaaat ctaatgaacc tgattctgca
     4441 aagtcatata atgcattttg ttcaaagaaa aatttctctt caaatttaat atagtcacta
     4501 taattagatt gacttatttc attgatataa ttgcaatcat tttcgttata agtaccaata
     4561 aaaaacttat ttcccattaa gtaatatata gctttcatat cattatttat tatatataca
     4621 ttttctttta catgatcatt attaaaatta aatctagtaa aaaatatacc ttcattcata
     4681 ttacttttta acaaaaatgg attttctcta taaaatactc ttgcaaattc ttcaggtgaa
     4741 tttacactgt atacacttac aaattcactt ttagaaatct catcaaatac ctcaaaatca
     4801 tacataggtt ctttatctgt cactaataga gagttaattc taaaaccagt ttcataacac
     4861 ttacttatgc aaaaagcaat tttacatata tagtatccat cattatcttc atataaagct
     4921 tcacttatat atctgccttg acctttatca cttaccacat ttttaagtaa tgttccattt
     4981 atattagtaa tatgcatatt tgcaatctcg tcacttccag aaaagtactt taaactttct
     5041 ctatcccatg ctataaatct catagtcata taatttataa attcaacttc ttcatcaact
     5101 cttttacata ttttattgta taatttttct atagttaaat ctgttttata gttttttata
     5161 atatcaatat actcacattt atctcctggc aatagcttat cataataaag attcttatta
     5221 ccaaaataag atactaaaaa taaagattca tccttcgtta attcaactct atctgaacca
     5281 aatcctccca tcaatctttc ttcttccata taagcttctt cttgtgttgg gttatttaaa
     5341 ctcacataat ctgctaatcc taatccctct gcatctaata aaaaatattg acaaaagtga
     5401 ttgttttcat catctatcca atttattata agacctaaac ttcccataag tctagaattt
     5461 gtagcctttg caaaattaaa attcatatag tcacatcctt taaactctaa aatacttgtt
     5521 ttttaatata taaattatta tacatatatt ttaacaactt agatacaatt tataatataa
     5581 tataaggaaa tgattaattg aggtggtctt atgaaaaata tagcagcttt ttttgatata
     5641 gatggtactc tttatagaga ctctcttatg gttgaacatt ttaagaaatt aattaaatac
     5701 gatataattg accaaaaaaa ttggtataaa catgctagag acacttttat ggattgggat
     5761 aaaagacaag gtaattatga tgattatcta ttagaaatat gtgaccttta tgttgattca
     5821 ttaaaaggat tagataaaac ctgtatcaac tttacaagtg accaagtaat taaattaaaa
     5881 gcagatagag tctataaata cacacgttca aggattgagt ggcatctaaa tcaaggacat
     5941 atagttatat ttatatctgg tagccctgga tttcttgttg aaaaaatggc aaaaaaatat
     6001 aatgtaaccg attttctagg aagtgattat gtctttgaaa ataatatatt tacaggcaca
     6061 gttattccaa tgtgggattc tataagtaag aataatgcta taaacgattt tgttgtaaag
     6121 tatgatttag atttatcaaa ctcgtatgcc tatggagata ctaatggtga tataaatatg
     6181 ctaaaaagag ttggaaatcc aatagcaata aatccaacaa aggaactttt atctcaaata
     6241 tcacttgatg aggaaatttc taaaaatgtt gagataatag tagaaagaaa agatattatt
     6301 tattctctat ctacagatgt aaatatagtg gatatttaat ttatactatc tattttaaaa
     6361 acttatatta tatctaatat ttatatctaa catataaaag ctttgactaa aaatcaaagc
     6421 ttttatatgt tgcactaaga atatattaaa tttagcttta tgttttaatg tatattcata
     6481 tatataattt accttatcca aactacaatt tcattaaatt taaagataaa aataagcaat
     6541 tattttttaa atagcatctt tcttaaccta ttattgtaat aacctataaa agaactgtaa
     6601 acatagtcat atactataaa ggctatctca aatgaaccta taataaatat gtttattgga
     6661 atataaacta ttgttcttaa taaaaaatac aatataagta tcattatatt tgcaaatact
     6721 aatttcataa aatactcaat atatatagac ctatcttttt ctataagata ttttacaata
     6781 ccatatattc caaaggtaag tgaatataca atccattgag acttacttgc catcactata
     6841 aatcctaaaa ctatagaacc tatataaaaa gcgattccac tcttaaagcc ccattccatt
     6901 attacaattg atactaaaag tgatgctaac cccataataa acaatgtatt tacaggaata
     6961 atatttgtaa gagtcaacaa tatcacattt aatgctaata aaactcctcc ataagcaact
     7021 tttatactca tatttatcat cctaacaaca agttattaaa tctccaccaa aacattcaca
     7081 acatgaatct aaacaccaaa gcttagcaca attttcacaa caatcgtcac ctagacaaca
     7141 acagcaatca tcacagcaac agcaacaaca tccatctaaa tcattacgtc ttcttctatt
     7201 ataattgtca gccctattgc tataatcatt tctatattgt gtataacttc taagtgcatc
     7261 actatattca ctattttcag gctccataaa ttttgctctt tttaagaagt cttcaccttc
     7321 ttcataatat cctatgttca ttgcagaaaa accagttaaa taataccact ctgcacattt
     7381 gtcagtcaaa gtttttaaaa aatcatatgc ttttttaaat tcactatttt ctatgaatga
     7441 tcttgctctc ataaaatttt cattattata agtattactg tacattcttt ccacctctac
     7501 tttctaatat attaatatat cttaaataaa caccagaata aattatattt tctattattc
     7561 caacattttt atttagattt agattatcaa ttcccctagc taaaaatcct aatgatgtta
     7621 ctattatttt ttttactttt tcttttaact catcattttt atcaatatac tctataaatg
     7681 gattatatct tcctttctta aaatcttcat ctaaatcttc ataggcatct agtagatata
     7741 tatacttacc tatattaaaa cctatcattc ttaagtttct ctcattttca tcttttttat
     7801 agacaaatac ttcacccatt atatttccaa atatactaga tacttcatct atatttatat
     7861 ttttatcttt ttctaactta tttaattcat ttagttgttg ttttatatac tctgcttttt
     7921 caggatactt ttcatatgct aattttaatt tgtttttata tatataatat gccaatttat
     7981 cttttatgcg tttatcatcc attaaattat cttccaattt ataatacgtt aaaagaatat
     8041 tcatacttgc tgcatattct gtaatatcat ttgtaattac ctttttcttt ttaaatggat
     8101 ttactataca cacttcctct gtacttatag actctgggtt atatactgct gttaataaaa
     8161 caattaaaaa tgttatatca tagttcaaag aaaacctaga gatttctcca tgatttcttt
     8221 ttaagtattt acatagtcca caatagtaag ctttgtaata atcatattct ctaaatgtta
     8281 aatccatttt gtttatttta acatatccaa acataaatac tcctttttgt actactttat
     8341 tatataaatt atatttattt tctaactcat ttattttata gtgcattatg taagttttta
     8401 ctctttttac ttactgatgc tatatagtcc ttttgactta ctacatatta tctctaagtt
     8461 acttatatca tttaatagta tattctttgc ctttgaacaa gtcatttttt atcccttatt
     8521 atttaaggtt caatcaagat ttaacaagct atatatttac attttttgta agtctaacat
     8581 aattaatata ttaaaaagat gtatttatcc tatatgttta tgtgttaatt agactttagt
     8641 aaccttaatt gaatctattg tttcattggt tagaaaatga gtgtatgcca tcaaacatta
     8701 actcgctcct cttttatttt ttgttaatta ttattatatc attaataaaa ttataattca
     8761 tttattttat atgtaatcat taataaattc ttatctactt ctcttttctt ttttaagtct
     8821 tctatattcg tctaagaatg ttctgttagg tatagttact taattacaat ctcatctatt
     8881 gttatactta catctttatt ttgctataag ctatcattta ttacctattt cttcttattt
     8941 tttctatttt agtggacatt taatttatga caaataaata tatttatttg attatattta
     9001 atacaaaact attcttataa cctttttaaa tcatatttaa catataatat taagtaacat
     9061 acttacttaa gaggaattat taaatgataa aatttgaaaa gttaaatatt attaacaata
     9121 aagatatgaa agaaatacta gatacatggg aatcatcagt aagagcaaca catgactttt
     9181 taagtgaaga aaaaataata tcaataaagc ctcaagttaa agaaggtgct aaatatgtta
     9241 gtaatttttt atgtgtaaga gacaaaaaag gtcttataaa agcttttatg ggaatacatg
     9301 attttaaaat tgaaatgtta tttgtaggta attatagtat aggaaatgga attggaaaaa
     9361 gacttgcaga atatgcaata gaagtattaa atgtaaatta tgtagatgtg aatgagcaaa
     9421 atcaacaagc attaggcttt tataaacata tgggatttaa agtctttaaa aaatctgagt
     9481 tcgatgaaca aggtaatcca ttccctatac tgcatatgaa attaaaataa caatataaac
     9541 tatagtataa ctaaataaat ataaatagag taataattga aaaatattac tctattatca
     9601 taaccttact ctcacttatc ttgttataat aattatataa tatattttta ggtcgtttaa
     9661 actgtatttt tagtttttaa ataacaaata ttttctattg ttgatttcca atgattttat
     9721 acaaaaatag tataattgtt atatgttact atagaagttt tatttatttt tcttactgtc
     9781 taatactact ccaataacta atccaaagga taaaccaata gctaagtttt taaataatga
     9841 acccaaaata acaccaaaac ataatcctaa cgccaaataa cttatatttt catttttcat
     9901 atattactcc tttaaattta attgtaacat tttaactttt ctaattgatt cttttgaagt
     9961 tttgactata tcaactaaac ctcttatctc atagttatta cactcactta gcactccttt
    10021 tactaatatt ttaagatatc tcccctaatt tataaacagt agtagtaaaa aatggttttt
    10081 aaacatatat tttcaaagtc taatatatat aaaactattt ttatgaatct ttactaattc
    10141 caactgctct taaaggaccg agtaacgaca ttctaacaag tatcagtacc atttcttcag
    10201 ggtaatctat aacctaacta aacctaaaaa ataaaattaa ttataaacaa aaaataaata
    10261 taataaaagg gcttacaaat tataagtcct tttatcgaac ataaaatcaa attattttcc
    10321 ttaaatagga aactttaaaa atatattcta attattatat cttagattga aaataattag
    10381 aaagttaagt taaaaataat gttaatttat atatttatcc taattcatac aattcaatct
    10441 tacttgtatt aaattactct tcaaataatt ggagtatatt caaaactacc tacagtatac
    10501 ttcaattctt tttttgcttt atttataacc aattcatcaa gcattacatc atttattgaa
    10561 catgatatag atttagatgc caataacatt gctttaaatc ccatatcaga acctgcactt
    10621 gcacaagatt gccatgtatg ggcagaaata ccaataggcc aaactgaaca agaacactgt
    10681 gctgtaggaa ttatgtaact aacatctcca atatccaatg ataatgatat acagttatta
    10741 tgagtaaatg tatcatctgt aacctcatca tgtaaattca tcttagtaat atccttattt
    10801 ccacttaata cactagaaac actacttctt ttatctatag acactgtctc agctaattta
    10861 tctgcaaaat agtagtcatc ttcattatag ttttgtacac ctactaattt catattttgt
    10921 gatagaatat ctgttaatat tgtatttgga atatagtcat atactccact tataatgtca
    10981 tattccataa tggtaccagt cattaatgct gctccttttg ctatatcaac aatcctacca
    11041 aatacatctc ttacatgctc cattttaact cctcttatgt aataccacac ttctgcaaaa
    11101 tcaggaacta tatttggcat ttttccacca ttagtagtta catagtgtac tctacaatta
    11161 tcaaatatat gttctcttaa ataattacaa cctatattca taagttctac tgcatcaagt
    11221 gcacttcttc cgttataagg agcttgtgct gcatgagcac taatcccatt atatctaaat
    11281 ttcacagagt aattagcaag tgttgggatt cttataggag tatttatatc aaatggatgc
    11341 caactaaaag cacaatcaat tccatcaaaa aaaccctttt ttatcatcaa tacttttcca
    11401 gataaatctt cctctgctgg acatccatag tattttatag tccctttcag cttttttagt
    11461 ttgattaatt cctttactgc aattacagct cctattgaac ctgtaccaag taagttatgt
    11521 ccacatccat gacctgcacc accatctaca ataggttctt tagtagtgga tactttttga
    11581 gacaaaccat ctaaagcatc atattctccc aaaactgcta taactggtct accttctcca
    11641 taactagcca caaatgctgt atccatacct tctaatccct ctatactaaa accatgtttt
    11701 tttaaacatt ctttttgtaa atttgaagca tagtattctt tatactgaag ctctggattt
    11761 ttccatatct tatctgatat atctcttaat tctccctgta tctcatctat atattccatc
    11821 aaaaactttt tatttaaatt atccatatta attatataaa cctccctgtt tctaataact
    11881 tatagattat cagccaaaat gactaatttt aactgattta aaaatatttt ctaccataca
    11941 accattttat acaataaaac ctcttgactt gtaagtttca ttttatcaag taagaggttt
    12001 tcaagtttta taaaattttt agcatgttaa ccaatcaagc atattaaccc ataatttatt
    12061 atagtatttc caatcagtaa attcttttgg accccagtga ggtgcacagt cagaactaaa
    12121 gatagcagat tttccttttc caaactcgcc aacagctaca aatgggtctc ctccaatagt
    12181 tgctaaaaca ggacaattat ctctagctac tgttttgtta tatcctaaaa actttggcca
    12241 ttctgttggt atacctttta atactggatg ttcagagtca ataacttctg gaattattcc
    12301 tgctggtttt tcaactctat catctttatc tatcattgtt attggtaata catctttgat
    12361 agcagtttct ccgaatctag cttttgcatc tattcctgta aatgacatat atccacctac
    12421 catgattaac gccccaccat tatttacata ctctttgatt agttcaagtc tatctggatt
    12481 actattgcaa tctataaaag tactattaga taataagaac gtattagaac ctatatcaga
    12541 taatattata cagtcatact catttaactc ttctaattta tacggaaaac tatctgctgc
    12601 tacatgtgca ggcatatgaa ctgtctcata tcctccagat tctattgctt ctttcaacca
    12661 ctttacagct tcttcataat gagttgtaac aaacgtatca aatcctttta tatgagttat
    12721 attttttacc caagattccc ctactattaa tacttttttc atttatatat tcctcctact
    12781 tttataagtt taatattaga cttgcataca taagtatact atctaaatac tccttaattt
    12841 caacatattc atcaattgaa tgacattgtt ctattgaacc tggccctaat ataagtgttg
    12901 gtatttcagc taaatttttc attactctcg catcattgcc agctgttgaa ccttttatct
    12961 ctaatttttt tcctagagtt tcttctagta ttttatgtgc attcactaca aaatcagaat
    13021 ccttgtccat ctcaaaacct aaccctgatt gatatatgtt tatatttggt ttattatctt
    13081 taagccataa atctccatta gcccttgtca ttatgacatt tgttacatca tttacaactt
    13141 gttcataact cattatattt ggcaagaagt gtacacataa attaaataca cacttatctg
    13201 gcacagtaga acctgctgtt ccaccattta ttacacctaa atttattgta ggtgaaggta
    13261 atagtggatg tttatatatc ataagccagt tatgttccaa cccttttata tcttgaagca
    13321 acaacatagc cttctcaatt gcatttacac cctcccactt actaccacag tgaagagaca
    13381 cacctttaac ctcaacttca aagaatacaa atcccatatg tgcaactatt aagttttgtt
    13441 ctgatggttc acaaattatg caacaatctc caccaatacc attcataact gcatttatgg
    13501 taccatttcc gccaccttct tcatctacta ctgacattat ttttacatta ccaggtacat
    13561 ttagaccact atcttttata agctttacag ctaatattga tgctataagt ccagatttca
    13621 tatcagcagt tccaagtcca taaagttttc cattatcttc tgtagcacga tatggattat
    13681 atttccactt acttatatca cccggtggca tagtgtctac atgaccatta aatacaattg
    13741 tcttaccagg taaatcatca ctatacttac aaattaaatt atatctatct tgataattgt
    13801 gacctagatt tccttcttta tatatatttt ttgctttttt aattaattct tcgcttattt
    13861 cttgtctatc tacactaaaa cctatgtaat ttgcaagttt ttcaatatat tcctgtcctt
    13921 ctttttcaaa tccacctagt attccatgac caacatcttc agtctttata cttacaagtt
    13981 cttttaaata atctatgtat tcttgttttt tactatttaa tgtatctaag agaatttttt
    14041 tcatatttcc tcctaagatt tatttttaca tttaaaattt caagtctaat ctcatctatt
    14101 taagccatag taaacttttt cacttagcat attcccattc aatgtataaa gatgtatgca
    14161 aattaaagta taaaaatata tacaaaaact caataatttt tatagtttat aagctaaaat
    14221 ttaattacta tttagattta gctgattttt ttaattttat attatttatc catatagcaa
    14281 ataacattac caaacctttt ataatcattt gattatatga agatacactt aataagttta
    14341 atccatttcc taatattcct attattccga cacctataca tgtacctact atagaaccag
    14401 aaccacccat catattagta ccaccaagca caacggctgc tatagcatcc aattctgctc
    14461 catctccaac agttggtgaa cctgatgcca aacgtgatga tagtattatc ccagctaatg
    14521 ctgttagtag tccagctagt gcgtatactt ttactataac tttatttact tttactccac
    14581 ataatctagc ggcctcttca tttccaccta ctgcatgtac atgacgtcca aaattagttc
    14641 tttttaatag aaaatgtcct gctattacaa ctataatcat aattataact ggtattggta
    14701 ttggtccaat atatcctcta ccgagcatct taaatgcatc tgtatttact gatataggtc
    14761 ttcctcctgt aaatacaaag cttgccccac ttattatcgt taacatggct aaagttacaa
    14821 tgaatggagg tagtttttgt gttgaaataa ttgcaccttt tatgactcct aatattgtcc
    14881 ctattgctaa tgcaagtatc atacctcccc atataggtgc attataattc actactgttg
    14941 tagcccaaaa tgtacctact aaagcaatta ctgctcctac acttaaatct attcctcctg
    15001 taattattac aaatgtcata cctactgcaa gtattgcatt tattgatatt tgtcttccaa
    15061 cattaattaa attgtctaaa gttaaaaagt tagatgaagc tacactcatt attataaaaa
    15121 ttattacaag tcctacagct gcactccctt ggtctctaaa tacacttgtt aattttgtca
    15181 ataatggaga agatttttct tctttatgct tagttattga actcattaat tttacctccg
    15241 aaagccaatt ttaatacatt attttcaacc atttcttcac cttctaaaaa tccacttata
    15301 tgaccttctc tcataaccat tattctgtca ctcattgata ttaattctgg tatttcagaa
    15361 gatatcatta ttatacttac accactctcc actaaatctc ccattagatt gtatatctct
    15421 gccttagcat ttacatctat acctctggtt ggttcatcca taattaatat atctggttgt
    15481 aataaaagcc atcttgctat tatagctttt tgttggtttc caccacttaa actttgtata
    15541 acttgattca tatgtggtgt ttttatcttt aaagcttcta tgtatttttc taaaatatct
    15601 ttttcctttt ttctatctat aattgattta aacttagata tcttttttaa cccagccata
    15661 gttgtgtttt ctttgacact catttgtaaa aacaatccag taccttttct atcttctgtt
    15721 attaatccta gtccattttc tattgcatct gatggagttt taaactttac ttcttcattg
    15781 tttaaatata ttttcccaga atcatatgtt ctaagtccaa atatagcttc tactatttca
    15841 cttctcttac ttccaactag tccacctatt cccaatattt caccttttct tatattaaag
    15901 ctaatatcat taaaaacatt gttcttagtt agactttcca ctcgcataat ttcttctttt
    15961 atttctactt ttctttttgg gaaaaattgg tctagctttc tatctatcat taaattaact
    16021 aattcttcct cagacgatac atctttggta ttcaaagtcg aaatcgtttt cccatctcgc
    16081 attatagtta ttctgtcaca aatctcaaag agttcttcca tcctatggga tatatatatt
    16141 atactaactc cactctcttt taaatcattt ataagtctaa aaagtatttc agtctctttt
    16201 ttacttattg aagaagtagg ttcatccatt attaatactt tagtttctga tgataaaact
    16261 cttgctattt ctaccatttg tttttgagct atactaagct ctttgactaa gctatttgga
    16321 tttatatcta ttcccatatt atcgaaaatc tttttagcct cttcattcat ttttttgtca
    16381 ttggttaaga ctttgccatt tatttctttt cccataaaaa tattttgtgc tactgttaat
    16441 tcgtcaaaaa ctgttagttc ttgatatatg gcatttatac ctatcttttt agagatatct
    16501 ggggatatat tctctatttc tttgccttca aaaataaatt ttccagaagt tttcgaatgt
    16561 gccccagtta aaatctttat cattgttgat ttaccagcac cattttcacc cagtagtgca
    16621 tgaacttcgc catgaaataa ctcaaaatta acattatcta atgctctgac accaggaaat
    16681 tctttagcaa tattacttaa cttcagaatt atattactca taatgacact cctttttaaa
    16741 taggatttct ttcaaataat ctcattttat tttactaatt cttaaagtct tttatatttt
    16801 ccttatcata aagtaaagct ggtactggta tattcttttc taccttttcc ccttttatag
    16861 cttttactac tgcttctaca gctaaacgtc ccatctcttt aggttgttgt tgaatcatag
    16921 caagaatagt tccatctgtt attccacttg atgcttcttc agttaagtca aatcctacaa
    16981 tcttaacatc cttatttttt gcagattcaa gtgcagcttt agctcctagt acactatttt
    17041 cagctgttgc atatattata tctacatctg gattagattg aattaagttt tctactgtat
    17101 taagagattc ttctctgtca tatcctggtt gtgaatttaa tatcttaaca tttgctgaac
    17161 cttttaatgc atctttaaat ccatctattc tctgcatttg tatttgagat tttaaatctg
    17221 tcactattgc tatttctgac tttccaccta acttttcatc tatgtatttt ttagtgtatt
    17281 cccctaattt tttaccagca tcataactaa ctgttcctac ataacttgta atattttcag
    17341 tatttaatac agcatctact gtaactactg gcattttttc aaatgctcct tctactgctg
    17401 gtactatagc cgaattatca gttccaagta ctatcattcc atctacattt tgttgtataa
    17461 aatcttctat tgctgatgtt tgcttagcta catcttggtc tgggtcattt actataactt
    17521 tcacacctaa ttctttagct ttttctttta ttccctcatc aatatctata aaaaattgat
    17581 gttgaagagt tattgtagat actccaatag ttaaatcttt cttgtctgaa ccacctttat
    17641 tatctgattt acttggtcct tccattgaac accctgttaa cattcctatt gctagtattc
    17701 cagcaattcc taaagataaa atttttctca ctctcataat taacctccat ttttaatagt
    17761 tttaaatttg aacaaattag atttttattt attatttaaa tatttttcaa catcttcttt
    17821 atagggcata ccagattgtg cacctagttt agttacagaa agacctgata ctactactgc
    17881 atattctact gctgtatata aatttttccc ttctgttata gccactgcca atgctccatt
    17941 aaatgtatct cctgctcctg tggtatcttg aacatcaaca cttatacaag atacatgctt
    18001 gatttcctca ccatcataaa atctagctcc attttttcct tctgttatta caagtttatt
    18061 tggatatttt tttaatactt cttctatccc ttcatttgtg tcaaaaacta tcttatattc
    18121 atgttcattt ggtgttaagt aagttacttt ttctattata tcttcattta gttttactgc
    18181 tggtgctgga tttaataaaa ccttaatcct attttcaaaa cagaaattca ctacataatt
    18241 tattgttttt aatggaatct ctaattgtag caatactata tctgcattct ttatctcttc
    18301 ttcattcttt ttaattaatt ctatatctac tagctcattc gtccctggta caacaacaat
    18361 actattatca ttttcacata atgttataac agcaacacca gaacttttgt gattatttct
    18421 ggatactaaa ctataatcaa ctttattcgt tctaaaattt cttattaact cctctcctaa
    18481 gccatcttcc cctatgcatg atatcatttt tacatttgct cctagtttag aagctgagat
    18541 agcttgatta gccccttttc ctccaggtga tgtaaaaaaa ctattaccta atactgtttc
    18601 tcctttttct ggtcttttat ctacagaaca taccatgtcc atgtttacac ttcctatgac
    18661 aactatgttt cccattacat tactccttta catatctatt tatgtctctc gtgctgttat
    18721 tcactttctt ttgttgaatc tcttatgact aattctggtt tgaaaatcaa ttcatcaaac
    18781 gattcttttt tatctcctct taaacaattt atcaatattt cactggcttt atatcctata
    18841 tcataagatg gctgttttac tgtggtaaga gaagggctta ttagacttga tgtttgaata
    18901 tcatcaaatc ccacgacact tacatcattt ggtatactta atcctctttc tttaagacct
    18961 cttatgacac ctattgcaat caaatcattt gcacaaaata ttgcatcaaa atctatcttt
    19021 tctaaatttt ttataaattc ttgtccccat tcaatcttat attttccttc aaatacataa
    19081 gcaggattgt agcttaaatt gcactcgatt agagcctttt tatatccttc taatctatct
    19141 actgctattt cattttgaag tggaccactt aggtatatta ttttcttatt tccaatatct
    19201 aataaatgtt ttgtagctat ataggcccct tcaaagttat ttattttaac aattcctttt
    19261 aaggtttctt tgttcatact tatcttctta tcaatcaaga cagttggtat ttttatatct
    19321 ttataatttg cttctttcca gtttgtattt gaagatgctg caaatataat tccatctatc
    19381 atcctctctg atagtgttct tattccttca tattcttttt tagcatcttc atctgtatta
    19441 cataaaatta tattgtagcc ttcttcatta gctttatctt ctacacctct tgatacatct
    19501 gtaaagaatg gatttcgtat atctggtata agaagcccta tagtattagt ttttttagtt
    19561 actaaacttt gtgctaattt atttggtaca taattttttt ccttcattat tttcaaaatt
    19621 ttttctcttg ttgcctgact tatattttca tctttattat taatgacttt tgacacagtt
    19681 gttttagaaa caccagccaa ttcgccaatt tcttttatag ttatactcaa gaagttcacc
    19741 cccaaaattt aggaaaccgt tttacttaac cggttaccta gatactatca catctttttt
    19801 tcatttgcaa ccattttata taaattttga tatttttccc ttttttcaaa atattgcaac
    19861 ttataattca attttaatat ttaaattaat ctgcaaaaaa aaattaatat acttttataa
    19921 ttatctaaaa gtatattaat taatttaagc agtatttatt aaagttcaaa tccttgctct
    19981 ataatcattt ttttatcatt ttcaatccca cttccaacag ttgtcaaata atcaccaaca
    20041 attgcagaat ttactccccc attaaatcca actttgtcat atccctttaa tgatagcctt
    20101 ccaccagcat accttatgta cacattagga attataaacc taaatactgc tgttgttttt
    20161 agtatttcca ttggttctaa tacatcataa ttttccattg gtgtattctt aataggattt
    20221 aaaatgttta ttggaaatga ttttacattt aattctcgta tttcaaaagc catttttagt
    20281 ctctgttctt cactctcatt cattccaatt ataccgccta cacatacatc tagcccagct
    20341 tttttagcat cttttatagt ttttatccta tctttatatg tgtgtgttgt acatatatta
    20401 tgaaaattat ctctacacgt ctcaacattg tggtgatatg tagtcacacc tgctgacttc
    20461 aacattttag cttgctcata atctataata cctaaagatg cacataattt taaattagta
    20521 ttttccctca atccttcata gatatttaaa atattattaa actcctttcc tgacatacct
    20581 ttaccacttg taaccaatga gaatctatgc actcctttac tctccatctc tttagctcta
    20641 tttaagattt cattgtaatc taataatgaa tattcttcta caccagtttt ataataagaa
    20701 gactgagcac aaaatttaca gtcttcacta catttgccag atttagcatt cattatcgta
    20761 cataaatctg cttttcttcc cataaaatat tctcttattt catttgcaga ttttaataga
    20821 atatcaaaat cgtttttatt atttgtatca aggcttatta aattaagagc ttcttcataa
    20881 cttatttctt tttctctcaa tactttattt tttaatttta ttatgtattt ttccatatat
    20941 cctcctattt gtcaacttaa tatttttatg tagtttactt attatatata gtattgcata
    21001 tataacattt attggtcaac tttattttat acacaagttt actatacaca aaaaaatact
    21061 gcttcaaaat aatattagta tatggattat acatattatt attaaagcag tattttttat
    21121 tagaatataa ttcttactgg tttataaaac tatccttgtc ttaactccat ccaagctttc
    21181 cattgtaata acctctaagc cttcatattc tctaaatagc cattttaaat ccttcatggc
    21241 ttgattaacc tgactttttg ttagattatt tataaaatat tcttttctag tttcctcata
    21301 ctctttgcta gtcaaaaagt ttcttagaaa attaaacgca aatacacttg gaatattgtt
    21361 tacattagcc ttcttgctgt tttccttctc atagtaaatt ttcataaatg catactcctt
    21421 tgatactttt agatttctct tacaataatt atatgcattt aagtgctact attcttataa
    21481 ttttattaat tcatattctt tacttcccat acccatttca catgcatagt ctattattct
    21541 agttccattt acatgaggat gttcatgttt gaaaacatca tgacccattt ccttgcaaat
    21601 caaatcatag catgcttgtt caatagctac agggtctgtt gatgctaata ttcctatatc
    21661 atgggcaatt ggtctacctg accaaggtac acaatcacaa agtggagtta cattcataac
    21721 aaaagttata taccctacct tgtctttttt atttgatact gctccataag cgtattctgc
    21781 catcttttcg acaaacacat ctgagtcact ttcccattgt atagttactg ctctagttgg
    21841 acagacagtt ggacattctc cacatccata acatacatca gaatctataa ctgctttttt
    21901 atccactata cttatagctt ttgtaggaca agaattaaca cactttccac aacctacaca
    21961 cttcttttcc tttactactg gagtaacatc agaatgttgc atttgttttc ctgctgcact
    22021 tgcacatccc atagctaagt tttttaatgc tcctccaaaa cctgctgctt catgaccttt
    22081 aaaatgactc attactatca ttgcagaaga attataaatt tctccaccta tttttacact
    22141 ttcaaaatgt tttttgtcta tttttacatt ctcataattt ctactatata atccatctgc
    22201 aattattact ggtgcattta caactgcata agcaaatcca ttttctatag cagttgtaag
    22261 atggtctaca gaatttgttc tactccctgt atacagtgta tttgtatctg ttaaaaatgg
    22321 ctttccttcg cagtctttaa ccttatcaac cacttgtcta actgccacag gactcatata
    22381 tgtagtattt cccttttctc caaagtgaag tttaattgcg acttggtcat ttttttctat
    22441 taaatctttg aatcctgctt catcaaataa tcttcttaca ttgtttggta cgtttttatt
    22501 ttgcgaattt gagtataaat cacaaaaata tacttttgac ttttccatat ctacacccct
    22561 ttaaaatatt tacttatact aattttatca cttttaaagt aatttttagt atattt
//
LOCUS       DAEOTL010000064        22583 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEOTL010000064 DAEOTL010000000
VERSION     DAEOTL010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22583
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.064"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            410..715
                     /locus_tag="KRH82_002764"
     CDS             410..715
                     /locus_tag="KRH82_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656034.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            1123..1812
                     /locus_tag="KRH82_002765"
     CDS             1123..1812
                     /locus_tag="KRH82_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656035.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIQYKDLIINISKYVVSKSGIALNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGMEKNNYIKT
                     LWGIGYKMEEE"
     gene            1812..2729
                     /locus_tag="KRH82_002766"
     CDS             1812..2729
                     /locus_tag="KRH82_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8656036.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLANSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            2802..3728
                     /locus_tag="KRH82_002767"
     CDS             2802..3728
                     /locus_tag="KRH82_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656037.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKLNSGEIVMFGKKVAETDFEILKKIGTIIENPYFYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            3725..4405
                     /locus_tag="KRH82_002768"
     CDS             3725..4405
                     /locus_tag="KRH82_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656038.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTLVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            4850..5551
                     /locus_tag="KRH82_002769"
     CDS             4850..5551
                     /locus_tag="KRH82_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBG8656039.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGKHTLDDVQETVNSSYVFDTIIDSLKEKITHNFLRNLHSSLIFNTTLN
                     SRGMSGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEDLYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
     gene            6536..7186
                     /locus_tag="KRH82_002770"
     CDS             6536..7186
                     /locus_tag="KRH82_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656040.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            7502..9568
                     /locus_tag="KRH82_002771"
     CDS             7502..9568
                     /locus_tag="KRH82_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBG8656041.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPNG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKDAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVVDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMNEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            9585..11540
                     /locus_tag="KRH82_002772"
     CDS             9585..11540
                     /locus_tag="KRH82_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBG8656042.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKASTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSEPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            11556..12746
                     /locus_tag="KRH82_002773"
     CDS             11556..12746
                     /locus_tag="KRH82_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBG8656043.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            13925..14299
                     /locus_tag="KRH82_002774"
     CDS             13925..14299
                     /locus_tag="KRH82_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656044.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            14301..15158
                     /locus_tag="KRH82_002775"
     CDS             14301..15158
                     /locus_tag="KRH82_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656045.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            15161..15799
                     /locus_tag="KRH82_002776"
     CDS             15161..15799
                     /locus_tag="KRH82_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBG8656046.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            16805..17539
                     /locus_tag="KRH82_002777"
     CDS             16805..17539
                     /locus_tag="KRH82_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8656047.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYN
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            18878..20134
                     /locus_tag="KRH82_002778"
     CDS             18878..20134
                     /locus_tag="KRH82_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBG8656048.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSEVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            20197..21390
                     /locus_tag="KRH82_002779"
     CDS             20197..21390
                     /locus_tag="KRH82_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBG8656049.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIAGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            21591..21971
                     /locus_tag="KRH82_002780"
     CDS             21591..21971
                     /locus_tag="KRH82_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8656050.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         8545 a         2435 c         3784 g         7819 t
ORIGIN      
        1 gattaaaaaa taaatgattt atagatgaag aactaaactt atagattaaa aaataaatga
       61 cttatagatg aaaaatcaag ctcatagatt aaagaataaa taacttatta gatgaaaaaa
      121 caagcttata gataagaagt ccatgcttat aagccagaaa atgaatactt taatagatta
      181 aaaaatacat atttgtgaat tatagaatga atgactccat aaactagaaa atttataata
      241 atatctatat gaaaattaga attattttat cacaaaaaaa ttaagttaaa taaatatgaa
      301 attacttcca aatatacttc caaaaacatg taatcgcata tataatataa ttataaaaat
      361 aataaatatt tttatagtag tagttaatta ttaataagga ggggtcaaaa tgcctagcat
      421 gattatggaa gttgtaggag tactatttat agctattgga ttaatcttga cattcattga
      481 aataaaagga aatttccctt ctttttatgg ttttggtcaa aattctatag ggaaaaatgc
      541 tgtaggtatt atagcagcag gaattgcttt aattttcttt agaaatggca tagatagcat
      601 agattctata gctacttatg gtgtattttt agcaatagaa cttgttgtaa tagttgcata
      661 tttcttaata agaaaaaaat ttactaaaga agataaacat ttaagaacta attaactaaa
      721 ttatctacta taaaattgga aaattaaaaa caaataaaag tttgttttta attatttaaa
      781 atccaaattt gattattttt aaagaaacta tgttctgtat aaaactagaa tgtggtttct
      841 tttttatgta taaaatattt tttagcaaaa gttaaaaggt gttttataat ataaaatagt
      901 taattgtaga tgttaataaa agaaaattat gtatatttca gataaagata agagagtata
      961 ctatatttta attctttttt caataaagct tattgaaaag aactttaact tagaagagta
     1021 tcaccaaatt gcagatacaa tatcataagc agttatttat tgacaaccct ttttaataaa
     1081 tatatcattt gaagtatact gacgaaaagg agttgaataa taatggacat cttattggtt
     1141 gaagatgata agaatattcg agaaatggta tacgattttc tgattagtga gaattactct
     1201 gttaaaactg ccattgatgg aaatacagct attgaaatat ttaaaaatta ttcatttgat
     1261 attattttac tggacttgat gttaccaaag tctagtggtt ttgaagtatt aaaatatata
     1321 cgaagtgtga gtgttgttcc tgttattatt actactgcga aagatagtga cacagataaa
     1381 atgctagggc ttaatcttgg tgcagatgat tatattacaa agcctttttc aatcgtagaa
     1441 ttgcttgcaa gaattaaagc taatattaga cgtgcaacag tgtacagcag ttcaagaaac
     1501 tctcaagata tggttattca gtataaagat ttgattataa acatatcaaa atatgtagtt
     1561 tcaaagagtg gaattgcctt gaacttaaca catacagaat ttgaaattgt taaattacta
     1621 gcgactaatc aaggacgtgc tttttcaaag gaacaattat acaacgctat ttggaaagaa
     1681 ccttattatg gaaatgaaaa tgtgctaaat actcatatta acaggttaag aaataaattg
     1741 tctgatggta tggaaaaaaa taattatatt aaaactcttt ggggaattgg ctacaaaatg
     1801 gaggaagaat aatggagtta tttttagttg taatttctat tgtactattt gctctctact
     1861 taaaagaacg aaataaatca aagaaaatgg aaagtgatta taagtatatc aattcaagac
     1921 ttcgtgacat aacaaatgat gatgaaatta attatatttt agtaccatct gatatttcga
     1981 ttgtaaaaga aacggcagta gatataaata aacttcttga aaagttttac agtaggcaaa
     2041 ttaattataa tagaagtgaa aaagcgatat tgcaaatatt tacaaacata tcacacgatt
     2101 tacgaactcc catcacagta ttaaagggtt atattgaaat gctatatctt caaagtcaaa
     2161 aagaagaatt atcttcttca atgagagcaa ctgtggaaaa aatgcaaaca aattcaaatg
     2221 agcttgttaa ttcaataaat aacctgttta atatggcaaa aatccaatct ggagatatga
     2281 tattaaatct tcaaaaatcc aatctaacac aattatgtca tgagattatt ttagagtttt
     2341 atgatttgct agataaagaa aactttaatg ttgaagttaa tattgaagat agacctatat
     2401 atgcaaatgt tgacacagaa gcattacaac gtatactcaa aaatttaatt gataatgcta
     2461 taaaatatgg ttcagatggt agatttttag ggatttcact atatgaaaag gaaaaacatg
     2521 tttttataga tattgaggat aaaggttcag gtatttctga aactgaaaaa gagcatattt
     2581 tcacaagagc ttatactgct gacagaaaaa aaggcaatgg tttaggtttg gctatttctc
     2641 aagggcttgc aaactctatg ggaggttcaa tttatgtaaa tagtagacct aatgtaaaaa
     2701 cagtttttac agtaaaattg aaaagttaga aaaaagttag atttaaaaga gagaaaagat
     2761 aattttattt tgtatactgt ttttagaaag gagggagtat gatgaactat atcatagaga
     2821 cccatcaatt aaagaaaata tataaagata aagctgttgt taatgctgtt aatattcatg
     2881 tgaaaaaagg agaaatttat ggatttgttg gaccaaacgg ggcaggtaaa agtacagtaa
     2941 tgaaaatgtt gctaaatctt gttaagctaa attctggaga aatagttatg ttcggtaaga
     3001 aagtggcaga aactgatttt gaaatattaa aaaagattgg tactattatt gaaaatcctt
     3061 atttctatga gaatttgact gctaaacaga atcttgattt acactgtgaa tatatgggtt
     3121 attataacaa agaacatata tcagaggtat tggaatgtgt cggattgtca aagcaatcaa
     3181 acaagaaagt ttcaaaatat tctttaggga tgaaacaacg tcttgcaata gctagagcaa
     3241 ttcttactaa accagaatta ttgattcttg atgaacctat aaatgcactc gacccagagg
     3301 ggataagaga aatgcgagaa ttattccgta agttaaatac agattatgga ataactatat
     3361 ttatttctag tcatattctt tcagaggtag aacaaattgc ggacactatt ggaattattc
     3421 aagatggtaa acttattaaa gaaatttcta tgtcagatat acacaaatat caaacagatt
     3481 atgttgaagt agatgtagat aatgtggaac ttgctggata cttgttagaa aaagaatttg
     3541 gaataaaaga ctttaaaatt acttcggaaa gttgtattga aatatatgat ttacgaaaag
     3601 atgtaaaaga aatatccaaa atatttattc aaaatcaaat tggtataaat agcattggac
     3661 gtaaacaaag ttctttagaa gattacttct tccaaactac aggtacagga ggtaaagaaa
     3721 cactatgata catttaatga aactagagct aaaaaaagtt gggctaaaaa gatatttttt
     3781 attttcaatg ctggggattt tcttatgtat gttttttgtc tttactggat tgaatgataa
     3841 atctacttca atatatgatt atgatgttac atttaggaca atcagtttat ttttctgttt
     3901 ttactatatt atattatttg ctgtgttgaa tgtggcatat ataataaatg aatatacaaa
     3961 taaaacaatc ttgattttat tctcttatcc acttgaccgt aaaaaactta ttttatcaaa
     4021 gttacttttg attacgactc ttatgatatc atcaatgata gttggatata tctgttgttt
     4081 tacattcgtt gttgtgttgg ataagtattt taatttagtt attggagatt ttcatatttc
     4141 aattttatct tattggatac caggagcaat taaaagtatt attgtatttt gctcattagg
     4201 tatatggaca ttagttgttg gaatgataag aaaatcaata cctgttaccc ttgtcagttc
     4261 aattattttt atcaatttaa gacaatttat tttagctggt acaaatacaa ctcaagacag
     4321 tttgatttct gtttttatta tagttggtat aactgtgatt ggtatatatt atatactaaa
     4381 tcataaagtt actgaaattg actagatact gtggctagga aggtagttat taattgtatc
     4441 ttcttgggat aataatgatt tgctattata tcagctatta ttaatattat tagagtttta
     4501 ataatattaa taatagctat atattttttc ttcttattta taaatttaat gatttatagt
     4561 cataaaatga actctaagaa gagataaaaa tacgttttat atgtttttag attaatataa
     4621 aatatcacaa tgaaatgttg tacaaagtga tatataataa ttatatgaac tataaaattg
     4681 actaaactta ttgactaata aattagatga aaagttgaga cttactgaaa ataaatacaa
     4741 tgaaatatat actacaagta ttaaattaaa tctgaacttt acatactatt agaataagta
     4801 ttataagatt ataatgattt aaaaatatta aaataattga gatgataaca tgaacaattc
     4861 ctttttagat aaattgattg agacaaaaga acttaaaaat tcactttata atgtgttaaa
     4921 acacaatttt ctttatcatt ctaataagat agagggcagt acttttacta ctgaagcatt
     4981 agcactttta ctcgataaga atgttgttac aggaaaacat actttagatg atgtacaaga
     5041 aactgttaat tctagttatg tatttgatac aataattgac tcactgaaag agaaaataac
     5101 acataatttc ttaaggaatc tacattcaag tttaatcttc aatacaaccc taaattccag
     5161 ggggatgtct ggtatatata aaactatacc caatatgata ctaggaactg atgtaagcat
     5221 agcacaacca tttgaagttg agccaaagct tgatgaatta attgaatggt actatagtca
     5281 gagtgaagta tctattaaag ttatagctga atttcattat agatttgaat tgatacatcc
     5341 atttcaagat ggtaatgggc gcataggtag atttgttatg ctaaaacaga tgttagaaaa
     5401 taatcttcct ataaaaattg tatcttggga tagtgaggac ttgtatagaa actccttaaa
     5461 ttcttgtagt ttaggtaatt atgtcccttt aatcgaatat ttatcaagtt tagaagattt
     5521 tagagaagta tataaaatgt tatggaaata attgtttgca gcaaaaaaaa gtttttatat
     5581 aaatatattt ttatctatgc tatttaacgc tgatttctta gttattctta gcttggacta
     5641 tatccactat tttaactata taaaatagtg gatatagttt aactatctct ttataactat
     5701 tcttatgtat cttagttgtt tcttaatatg gggacagttc ataaaactaa aagtgatttt
     5761 taattttatc atttataatt taccattaca tcagaaaaat acttatcatt agaattttca
     5821 taaaaggtac ctattttttt caattaacta aatcaattct attagtctta atctttcata
     5881 tttcaaattg ataatataag aaaataaaaa ataaaaaatt ttaaattttt tatttattgc
     5941 gaaaaaaata aaaaggtgct atactttttg taacatatta ttcaaattat taagagatag
     6001 taaacattta tagtttaatt tgtagtacac tagcatgatt tgcagaacaa tgaattaatc
     6061 tatagtataa tagtttaatt taaagtacaa cgatttaatc tatagtacaa taacttgatt
     6121 tgaagtacaa cgatttaatc tatagtacaa taacttgatt tgcaatacaa tgaattaatc
     6181 tatggtataa tagtttaatt tgaagtacaa tgaattaatc tatagtataa tagtttaatt
     6241 tgaagtacaa cgatttaatc tatagtataa tagtttaatt tgaagtacaa tggtttaatc
     6301 tatagtataa tagtttaatt tgaagtacaa cgatttaatc tatagtacaa taacttgatt
     6361 tgcaatacaa tgaattaatc tatagtataa gagcatgatt tacagtacaa taatttaaat
     6421 tgtagtacaa aagtactatc aaataagaat ttctacttta aaaatattac taaaagtaat
     6481 taaagtccag taattcaata taatatggca aaagaataga aataaggtga gagtagtgaa
     6541 agtaaagtca aatttagatg aaattttata tcataagatt attgaaagtc ttattcgtgg
     6601 tgaatactct gtaggtcaaa aaatattact aaatgacctt tgtgaaaaat ttgaagtaag
     6661 cagaacacca gttgtacaag cagtaaaaat gctaaataaa gatggagtgc ttactattat
     6721 gacaaatggt aaagtgtacg taccagagta tgaatatgat atggtaaaac aagtttgtga
     6781 aacgagaaca ctgattgaaa catatgcttt agaaaaaatg atgcaagaag aggaagaggt
     6841 ttttcaacaa aagctagatg taataaaaag atactctgat aaatgcgagg agtactatcg
     6901 tcaagaaaaa tctgtagaac ttgcactagc agatttggaa ttacataaag ccattgtaga
     6961 aggggcaaat aatgagattt taaatgatgt atatgttggt atacaaggaa gatttatagt
     7021 agtgaactat ttaattcgac cattaaaaaa tcgtaattat gaaggaacag tacaagacca
     7081 ttttgaaata ttaaaattca ttgaagacag agatacaaaa aaagcagtag ataaactaag
     7141 aaatcatatt caaggaacta ttaaaagatt ctgtgaagat gaataataag ttttgaagtt
     7201 actatatata cttatctatt aagttgctaa atgtagtcta agtataatct aattatagtt
     7261 taaacataat ctaaatataa tctaataaat ataatctaaa tatagtgtaa ataagtctaa
     7321 gtatgaatta aatatagatt aagtatggac taagtataga ttaagtatga attaagcatg
     7381 gattaaatat actttaaatt acaaatatta caaggaagcc agaaggcttc ctaaaaaaat
     7441 aacctttata aaatttttta ttttaaattt aaaatttttt attttaaatt taaaataaaa
     7501 aatgaaagag gtggtaggga gtttgaaaaa aattactaaa gaaaggatag aaaatactat
     7561 gaaaaagcta tttacgagtg aaacattttt ggaatatcaa tttataagtg attgccaaat
     7621 atcaccaaat ggaggatata cagcatttat tgtaaaaaaa gctgatatca aagagaatgg
     7681 ttacacaagc caagtttata tattaaacaa taaaactggc gaattaaaac aaataacgtc
     7741 tataaactct gttggagcat atgcctggga agatgaaaat actatcttgt tccctgcttt
     7801 gcgaaatgaa aaagtaaaag atgctgtcaa aaacggtaag caatgcatga gttactatgc
     7861 tttatcttta aatggtggag aagcagaaga actttttaga ctccctatca aaggtggtaa
     7921 attgaatcct ataggaaaag gtttgtatgc agttgttgat tcttatgaca atgaccgacc
     7981 tattgtagag ggattgccag aagaagaaca acagaaaaaa ataaatgctt ataacaaaag
     8041 acattatgaa catttcaaag aaattcctta tgctgtcaat ggggagggat atattagcag
     8101 aaaaagaaaa cgcctatatg tatacgacag taatataaat gagttgaagg caattacagc
     8161 acctatgttt aatgttgtag gtatgaaaat aagtgatgga aaaatcttat atatagggca
     8221 agagtttaaa gatgtaaaag gtttgaaaaa tggggtctat gtatttgata caaacacaaa
     8281 cacaaatgtc tgtatattag aaaaagataa gtatattata aaaggttttg aattatatca
     8341 aaatcaagtg atactaaacc taactgatgc tttatcttat ggaaatggag aaaatggaga
     8401 tttttatact attgatattg atacgaaaga aatgaaactt ctttcagggc atcaacatca
     8461 ttgtattgga aatacagtaa catctgatgt taaaatgggt gctggtcaga caacaaaggt
     8521 agatggagaa tatatttatt acacttctac agtagatatg gactgcatta ttgaaagaat
     8581 acatattcca acaggaaaac aggaaaaagt aacacagaca ggttcagttg attttataga
     8641 tgtaaaagat ggcaatattg tatgtgtggg ttgtttagga aatggattac cagaagttta
     8701 tacagtagag aatggaacat tgtgtaagaa aacacattta aatgaccata ttttagagga
     8761 atataaaatt tctgtgccag aatacataga gtcaaaagga agttctaaat gggaaataca
     8821 aggatacgta tataaaccag tagattatga ggtggggaaa aaatatccag ctgtattggc
     8881 gattcatgga ggaccaagat tgacatatgg accatatttt atgaatgaga tacaggtatt
     8941 tacaagtgca ggttactttg tattcttctg taacccaagg gggtctgaag gtcgtggcaa
     9001 tgcttttgca gatattagga aacagtttgg agatattgat tatatagatt ttatggaatt
     9061 tacagatact gtacttgaaa aatatacaga cattgataaa acaaaattgg ctgttgaagg
     9121 tggaagttat ggtggattta tgacgaattg gataattggt catacaaacc gttttgctgt
     9181 tgcttgtgct cagcgttcta ttgcaaactg gagtggcatg gagggtacaa cagatattgg
     9241 ttattatttc tgcaaaggac aaacaggtgc ttctcatatg gaaaaccacg agcttcaatg
     9301 gaaacagtca cctcttgctt atgctgataa atgtgttaca ccgactttat ttttacatgg
     9361 tgaaaaagac tatagatgct atatgcaaga agcattccag atgttttcag cattgaaaat
     9421 tcatgggtgt cctacaaaac tttgtctatt tgaaggagaa aaccatgaac tgtctcgttc
     9481 tggtagacca aaacaaaagc tacaaagatt agttgaaatg ctagattggt tttcggtata
     9541 tataaaaaaa gataacatag gacagtagaa aggagaatat aaaaatggaa aaaataaaga
     9601 ttgaaagttc agatattttt gaatatatat tccctcatga tatttcttgt tcacctgatg
     9661 gaaagcatat tgcttatatt atatcaaata tcaacgagga aaaagactgc tatgaacatg
     9721 acttatatgt gatggacatc aaaacagaaa aacaaataca tatgactcaa acaaaagatg
     9781 taacatcatt tagttggatt tctaatacag aactactttt tacatctaaa agaaataagc
     9841 caaaagcaag tacaacagat ttttacacta tttctataga aggaggagaa gcaaaaaaag
     9901 cattttctat tccaaaagct tgtagcgtac ctgtatcact tggaaataaa ttgtggttac
     9961 tgacaacaaa aaatccaacg gattctaaaa aatcagaacc agatagggca gtagagggtg
    10021 tagattattg gacatttaca gataaacctt ttataagaga tggagaaaat ttttctcaaa
    10081 gaagacgtgt aacattagaa ttatatcaag aaggtgaaaa tataacaaaa gccattacac
    10141 caaaattttg tgaagtagca ggtgtagacg tttcttctga taaaaacaga attttatata
    10201 ctggtcagat ttatgaagat tgtgcaactc ctttttctgg actttgggag tatcatatag
    10261 acagtggtga aaccaaagaa cttgtaccac aaggaaagta ccaaataagt ttggcaaaat
    10321 atattggcaa agataaagta atgttgcaag cttcaacatt agaccgttct attacacaga
    10381 atcatgatat ttttatactt gatttgagta ctagtgaaat aaatatgatt gctagtccag
    10441 atggtatgta tgctacatta ctggatgtag atgcagtata tggtggtgga cgtagtaata
    10501 aagttatagg agacaaattt attggtgcaa gaatttgcag aactatgaca gaatttaatg
    10561 agtttgatac aaagacaggt aatatacgta tcatcacaaa agtagatgct tttacatctt
    10621 ttgatattta cgacaacacc atgtacacag taatgttgaa agattatgag ttagcagaaa
    10681 tatatagcat tgatatgact acaggtacaa tgaaaaaaat gactgctttt tctgaaccat
    10741 atttagatac tcataaggtt tcattacctg aaaaattgac gtttgtagca aaaaataaag
    10801 aagaagttga tggttttgtt ataccgccta tagatgctaa agaaggcgaa aaatatcctg
    10861 ctgtattgtt cattcatggt ggacctaaat gggcatatgg ctatatgttt acacacttga
    10921 agcagtgtgt aacatcaaag ggaatgtatg tgatttattg taaccctcat ggtggtgacg
    10981 gttatggtga aaaattctta gaaatggtag aaagatgggg gtatgttgac tatgagcatc
    11041 ttatggaatt tgtagatact tgtattgaaa aatatcctgg gattgatgca gaccgcttag
    11101 gggttgcagg gggaagttac ggtggttata tgacaaactg gataattggt catacagacc
    11161 gtttcaaagc agcagtttct caaagaggta ttagtaactt gattacagct tctttaatta
    11221 ttgactttgg ggatagaatt atgaagcaga cttgtggaga taagacgcct tggaatcatg
    11281 aggaggttct ttggaatcat tcacctatta aatatgtgaa aaatgttaag acaccaacat
    11341 tgttcttaca tagtgatagg gattatagat gttttatggg ggatactttc caaatgttta
    11401 cagcattaaa acagcttggt gtagatacag aaatgtattt gttccacgga gatacacatg
    11461 gattgtctag aaatggaaga ccatctaata gaattgcaag agcaaatgct attgtagatt
    11521 ggtttgaaag atatttataa taagggggtt attctatgag tgatatgtta ttatggttta
    11581 gtgtcgtatt agttttattt gctattgggg atttaattgc aagcaaaaca aaagcaaaag
    11641 tatcagctgt atttgttaca ctacttttat ttttgattct atttgtcaca aaagcaatac
    11701 cagctgatat tattgaaaaa gcaggtatga ccgcagcagc tagttggagt gttccaatga
    11761 ttatgtttag tatgggaaca atgttgaatg ttaaacaatt tatagacgaa tggagaacag
    11821 tattgacagc atggcttgga attgtagcag ttatagtctg tgtctcatta tgtattcctt
    11881 tgtttggaaa atcaacagta ttgacaagca taccagttat aaatggagct ttacctgcta
    11941 ctactattat gacacaagca gcactagaaa aaggactgac acttgcagca gctacagcaa
    12001 cagttgtatt tgcaattcag aagtttattg gtacaccaat agcttcaaga gcagcgttac
    12061 aagaggcaaa ccgtctttta gtagaatatc atgaagcaaa atcaaaaggc attgatttag
    12121 caaatgttga tactgataag aaagaagcag agaatacagg cacaaaagta aaacaagctt
    12181 tctgtgaaaa atacgataaa tattattcta caaatgtttg tatatttttt atagcattat
    12241 tctcttatct agggtatgaa ctttcagaga ttattcatgt aaattattct attgtatgtc
    12301 ttgttgttgg tgttattgta acacgtattg gtattgtacc aaaagacatt ttggaaaaag
    12361 gaaaaatcaa gggatttatc aacatggttg tgtttgcagc tgttattcct tctttagcaa
    12421 aagtttcttt gacagattta attagtcttt ttgtaccaat tgtaggtatg tttgcagctt
    12481 ctatcattgg tatattcctt atgatgaagg tgttaccagg ttggaaaatt atcggttcta
    12541 aacctcttgc ttttggagta gggttttgtc agatgttggg attcccaact acatatttaa
    12601 tttcaaatga agtgtgtaat gctgttggag aaacggaaga agaaagagca tatttgatgt
    12661 ctaagattat gcctaagctg gtagttggtg gtatggcttg tatgatttct attgtggtag
    12721 ctggtcttat ggtaccaatg ttgtagatag gtttcatagt taaaaaagtg gtgttaattt
    12781 ataggagaag ctaaaaagta gtattaattt ataaataaag ctagaaagtc agtattaatt
    12841 tataaacgaa ttttatatta gttaatttat tataagaata ttttcttttt agcattataa
    12901 tcttgatttt atcaagaaac agatttttta tttgctattc taatagttac agtttatttt
    12961 tattttctaa aacaaaactt taacttgatt tatctataaa tagggtattt aataatattt
    13021 ttggaaaatc tttagaaaga attaaaaaga ggagaaaaaa gggagtgcca caaagtgaac
    13081 tttttagttc taaggcactc ttttttgtac gaaatcgaat atattttcaa agttttaaaa
    13141 gtgagaaaga gacttatctc tagtttgaga tagccaattt taattattaa aattattttt
    13201 tgttttattt atcaaagagt attcgtgttt tagaagttag tattttttat tttatatata
    13261 caaggttttc cgtttctaat gttttctttt ttaaaataat tagggtattc aattatggta
    13321 aaaggtggat ggtattttgc agtgatatta tttaaagcac agtattgaat gttgaaattc
    13381 tcacatttta gagtattatc ttttttaatc aaaaaaatct tctatactta tagcaaggtt
    13441 acttctgcaa atattccatg catcataata tccaaattta aattttttta atatagagtt
    13501 tacctctagt ctacactctt gaataactct ttcctctatc caaattctta taaattcatc
    13561 ccatttatta ctatctattt attactatct aaatttttta gtatgtttgt aattagaaat
    13621 ggatttattc ctttatgttt tttataaata gtttataact taatttatca tcaaacaaat
    13681 cattcataca ggattcctct tttttttaga tattcaattc ttacttttaa taaatattta
    13741 atacatccta tcttatgtgg ttttaaaaag tgtttatagc tatcaaaaat ctctaatatt
    13801 tcattcatat ttattttgtc atagtaatat tttacatctt ttatattgac aaaaaagtgc
    13861 tctaagtgta tagtgtgtat ataacaacat cacactgaaa atgataaaaa gggggtgata
    13921 aaaaatgaaa gtgctcattt ctaacacatc agataagcca ttataccaac aaattaaaga
    13981 gcaaattaaa gaagcaatat ttactgaaga actgaaagaa ggggatgcaa tgccatccat
    14041 aagaaatttt gctaatgatt taaaagttag tattttgact attagacgag tgtatgaaga
    14101 acttgaaaat gaaggctttc ttacacgcca agttggaata ggaacattta tttcaactgg
    14161 aaatttagaa atactaagag actcaaagag acgtatagtt gaacaaaaaa tggcagatat
    14221 gattaaggat gcaaaagcac taggaattac acagatagag ttacaagaaa tgatggatat
    14281 tctatatcag gaggattaat atggaaaata ttttagaagt ttataactta aataagactt
    14341 ataccgattt ttcattatct aatataagct ttgcattacc agaagattgt ataactggat
    14401 ttataggtgt taatggagca ggaaaaacaa caacaatccg ttcgatattg gatgtcgtaa
    14461 agcgtgatag tggaaaaata aaaatctttg gtaaagattt cgatggaaat gagaaggaat
    14521 taaaaaatcg aattggagtt gtatttgatg attcatattt ctatgaggag ttgtcaatgg
    14581 cagaaatgaa aagtattatt gcaccttcat atgataattg gtgtgaagaa gattatcaac
    14641 aaaatatgaa gcgttttaat cttaacccaa aacaaaagat tgatacactt tcaaaaggaa
    14701 tgaaaatgaa atttgcttta gcattagcat tatcgcataa agctgagttt ttaattatgg
    14761 atgagcctac aagtggttta gacccactaa tccgtagtca gatacttgac atactaacag
    14821 gatatatgaa gaaatgtggt cgtggtgttt tcttttccac tcatataaca tctgatttag
    14881 acaaaatagc agatatgatt gttatgattg acaatggacg tattatatta gagcgtgaaa
    14941 aagatactct attggacgaa catagaaaag taaaagggga tattcaattt ctaaatgatg
    15001 aaaccaaaaa attattttta aatttagaaa ttacaggtta tggttttata gggattacct
    15061 caaaaattaa tgaagtgcaa aaaaatatgc cagatatttt aatagagcgt cctacaattg
    15121 aagatattat gcttgcatat attgaaagga gagagtaatt atgttgattc atttagttaa
    15181 aaaagatatt ctgattgtaa aaaaatatgt attgttgata ttatttattg caataggaat
    15241 cccattattt atattatggc gtttacctcc atttgcacaa atattgggat ttgtactatc
    15301 aattatattt tcagaattta tgctgtgtca gtatctatta ttaaaggaga gtcaatattc
    15361 aaaagcatct gtattacttt gttcaactcc ttatcctaga cgtggcttag ttcaatctaa
    15421 gtatgtttta tttgcaatgg tatttatcta ttgtacatta gtttactgga ttgaaaattt
    15481 acttattcca caaataggaa cttttgactt gacatatatt ttgattgttt tattaataag
    15541 ttctattatt tatggagttt atatgcctat tcaatataaa ttaggatatg aaacaacaaa
    15601 attctttttc gtggtgataa tcatggcttc atcatttgta ttaccattaa ctatagctca
    15661 cagcaatttt gaaattccat ttatatatca gtatccatcc atgatagtga atattgtatt
    15721 gttcctttta agtttaatta tactgttagc ttcaatgttt atttctatta aaatttttag
    15781 taataaggag cttgtataag gtaaggggga cttttatatg ccacatttgc cagattgggc
    15841 tgttttactt tgtatcttac ttccaatagt atataaagct tgtcagatat ttaaaagtaa
    15901 aaaatagagt acatatttat attgccattt ttattgagta aagttagatg gtatgaaaag
    15961 gttacttgaa aataaagtta cttggtgtgg cagagtaaca tcataatatt atagattata
    16021 tgtttcttgt gaatcaattt gtatttttta atagataata tccagtaatt ttattttcca
    16081 ttgattattt ttcaattatg agtatgattg tgtgtattgt ataccatttt ttaagatgtt
    16141 tttaaaaaat tatatcgtca aaatataaat ctaaggaatc ctataaataa agcttttcaa
    16201 ttttagaaaa ctaataaaaa gtaggaagtt aataaaaaga agctgtctca aaatagagat
    16261 aagcttcttt ttcattgctg aaatgacgaa aatataattg gtttaatata aaaaagagcg
    16321 ctttatgaac tatttatttt gaacagtaga tacacttgca ctcaatttag ttactcctaa
    16381 gctttatgaa ctaaaagttt attttgaagc ctatttttat taaaagagat tttatttttc
    16441 taaataatca tctatataca gtattgcgtt tcttttattt attcataatt tattttctta
    16501 ttaaagtttt tctatattca tattttccat attactttac ttttaatttt atacgaatta
    16561 tcaaaaataa aatagttatt agaaaaaaat aaaagtaatt gcaaagcttg caattactta
    16621 cttctatatt aattactata ccataaaata acaaaaaaat caagtcgagt aatccttcaa
    16681 cttaagtgat atactaggta ttaataattt ttaattaata aaatataact agaggaaaat
    16741 ctacattttc tcaatttctt taattaaatt gacctctaat taagtaatta taaggagaaa
    16801 aattatgaat ttagcaaagg gattagatgt tttaaaaatt tcatcaaatg tattcggtga
    16861 agataaagtt atgtatattc ctgtaatcta cacagaagat gatgcaacac ttattgacac
    16921 aggtcttccg ggtcaaggtg atttaataat tgatgctctt aataaaagta acacgagctt
    16981 tgataggtta aaaaatataa taattactca tcatgatata gaccatatag gaaacataaa
    17041 ttatctaaga gaaaaatcta agaataatat caaagtatat gcatacaaaa gtgaagtcag
    17101 ctatataaca ggagaagaaa ctccttttaa actttatatg ttggaacaaa tggtagataa
    17161 aattgatgat aagatgctta gtatgctaaa tgttatggga cttggattta aatcatcata
    17221 tactaaagta gatgtgtcat tagataacca tgaaaaattg aatctaggtg aggaaataga
    17281 agttatacat acaggaggtc acactagagg tcacatatgt ctttatttaa aagagtctaa
    17341 agtacttatt gctggagatt tgttacaggt agaaaatgga gaacttaagc ctgttgatgt
    17401 gatgtacagc aacaaacaag agttaaaaga tgctattaaa aatataagta attataatat
    17461 agaaacgata gtttttagtc atggtggatt atatcaaaga aacataattg gaacattgaa
    17521 aaacctaatt attgagtagt actatatgat ttacaataat ttcttaaatt acttaaaatt
    17581 atatctaaag atgtagaatc aaaattaaat ataagtaata agaattttgc tttaaaatta
    17641 tacttaagtg ttaagggtga tatgtagtat tacaagtatt ttagaatata gttttttata
    17701 gtaattttaa ggttctacaa tacttcagtt gaaaaatatt taacagcata gtataatggg
    17761 aaagaaaata ctttaaataa actttagtat acaaagtgaa gaaaaatatt taaattatat
    17821 ataatattgt agagtgaggt aaaatattta agttatatat cataatacag agtgaagaaa
    17881 aatatttaga taatgtacca taatacaaag tgagtaaaaa tatttaaatc atgtatcata
    17941 atgcaaagcg aagaaaaata tttaaataat gtaccataat gcagagtgag taaaaatatt
    18001 taaataatgt gttataatac aaagcgaata agattattta aagcatgtat tataatataa
    18061 agtgcgtaaa aatatttaaa tcatgtatca taatacaaag taaaaaagat tatttaaacc
    18121 atatatcata atgcaaagtg aagaaaaatg tttaaattat gtatcataat ataagcagag
    18181 tgaagaaaaa aatttaaata atatatcata atgtagagtg agtaaaaata tttaaatcat
    18241 gtatcataat ataagcagag tgaagaaaat atttaaatca tgtatcataa tataagcaga
    18301 gtgaagaaaa atatttaaat aatatatcat aatgtggagt gaggaaaaat atttaagtta
    18361 tgtatcataa tacaaagtaa agaaaatcat ttaaattata tatcataaaa ataatatgaa
    18421 atattgaaca ctcataatat tagagacttt aatattttaa ttgataggtt atattattta
    18481 taacattaaa aatacaattt acataaaata gacatatgaa aaataaaaaa ttatataata
    18541 attatgggaa tgaggttctc ccttggatga taatatccta aactgccaat gagctgatga
    18601 cttctatgat atcatagatg ccaccagctt tttttgttgt ttaaatcaat aaaatggagg
    18661 tgaagtactt actaaatttt tattttttaa atttgaagaa atatttaatt aatagaaaaa
    18721 atagtagatt atatgttaat tattttatta agaatgggtt aagagtgtac ctatatccta
    18781 tcaatttaaa aaacaattat gatagtcatt acattgacta cagttgatgc aataaaactt
    18841 tcaaaaaatc ttatgatgca aatagaaagg aattaaaatg atagaaaaat ttaaaacttt
    18901 aatatggatt aaaatgataa taagaattaa aagcgtttat aaaacatatg gtggactatt
    18961 ttttttagga ctcataggta taccagttgg tgcaattata ggtcttatag acaccatatt
    19021 tggaacggtt cttctaaaag ttacagatat tcgagaaaca tatccaatgt atctgatacc
    19081 atttttagca gtagtaggag ttgttattgc ttattgctat tttaaatttg gaggaaaaag
    19141 tagtaaagga atgaatctaa tatttgaggt agggcatgga gaagaagaaa ttattccttt
    19201 aagattggtt ccatttataa tatcaggtac atggttaacc catttatttg gtggtagtgc
    19261 aggacgagaa ggagttgctg ttcagattgg tgcaactttt tcacattggg taggtaaaag
    19321 gttgcctata aaaaatgctt ctagtatttt tctagtaact ggtatggcag ctggttttgc
    19381 aggattattt gagacaccaa tagcagcaat actatttgct atggaggttt tggttgctgg
    19441 ttcactggag tatcaatcgc tttttcctgc gtttactgct tcttttacag caagtgcagt
    19501 atcaaaagct ttagggttag agaaattttc ttttgcactt tcttctgaag ttgtatttga
    19561 cttgtcaata ttttggaagc ttattgtttt aggaattatt tttggaatgg ttggtggagc
    19621 atttgcatgg tgtctgaaat tgtcaaaaag aaaaataggg aatagattaa aaaatcctat
    19681 gataaggatt gctattattg gagtatgtct tagtgtatta ttccttttat tttataaagg
    19741 aagatattca ggtttaggga caaatttaat tcaaaatagt ttctatggtg gagaaattta
    19801 ttcatttgac tggctgttaa agtttatact tacaatactg actttgtcag caggttttca
    19861 aggaggagag gttacacctt tgttttccat tggagctagt cttggtgtat tgttagcagg
    19921 attttttaat ttgccaattg aattagttgc agcgcttggc tatgctagtg tctttggtag
    19981 tgctacaaat actttttttg cacctgtatt tataggggca gaagtttttg ggtacagcta
    20041 tttaccttat ttctttgtag tatgcgctat ttcatatata tttaatatgg ataaatctat
    20101 ttattcacta caaaaaattt caacaaaaca ataaataaaa caacataatg tatgattaga
    20161 agagaaagaa tattagagaa aggatagggt aggaatatgt tgacaagttt agctttgatt
    20221 tttttattag gaatggcctc gggaggtatt tttaagagga taaagttacc taacttattg
    20281 ggaatgttac ttacaggaat tatattaggt ccatatgttt taaatttgat tgataattca
    20341 atactagata tttcttctga ccttagaaag attgcattga ttattatatt aacaagggct
    20401 ggattatctt tagatataaa cgatttgaag aaagtgggaa gacctgctgt acttatgtgc
    20461 tttattccag ctacttttga aattatcgga atgatagttt tagcaccaaa gttactaggc
    20521 gtttctatat tggaagcagc agtcatgggt gcagtagtag gagcagtttc tcccgcaatt
    20581 attgtaccta aaatgcttaa attaatggaa gaaggttatg gtacagaaaa aagtattcca
    20641 cagatgcttt tagcaggaac ttctatagac gatattttcg taattgtgat gtttacagta
    20701 ttcacagggt tggcacaagg aaatagtata tcagctatta gttttttaca aattccagta
    20761 tcaattatat taggtgtaat agctggagca gtgattggaa tctgtttagc agtatttttt
    20821 aagaaggttc atatgagaga ttctgctaaa ggggtgttgc ttttaagtat ctcattttta
    20881 atgataagtt tagagactgc tttagagggt attgtgccat tttctggatt attagcagtt
    20941 atgagtattg ggattttcct tcagataaaa tatcgtgtag ttgcaagaag attgtctata
    21001 aagtattcga aactatgggt tggtgctgaa attctcttgt ttgttttggt aggggcaaca
    21061 gtagatataa gttatgcatt taaagcagga attggagctg taattttaat atttggagtt
    21121 cttttattcc gtatggtagg agtattcttc tgccttatta agacaaattt gacaataaag
    21181 gaaaggttgt tctgtatgat tggctatatt ccaaaggcta cagtacaggc agcaatagga
    21241 ggtgtaccac ttgcaatggg gatggcatct ggacaactta ttttgacgtt agcagttcta
    21301 gctatactta taactgcacc tcttggagct tttggaattg atgtaactta taaaaaatta
    21361 ttaacttctg taaaaggcga gagtaagtaa aaataaagat tattttaact ggtaagttat
    21421 attttggaaa aggattatac tattgaatac aatataaaaa aatcatttgg gagattaaga
    21481 aggtagaagt taagaacaga ttttaaggta tgttatgatt attagaattg attttgtgaa
    21541 attattattg taatatttaa ttatatagat aaagaagcgg agtgataact atgtgtttaa
    21601 aaaaattatc aaaattagag ttagttatta tgaaatttat ttggaattta gatataaaaa
    21661 ccaattcata tgagattatt gattatatga aagaagaaca taatttacca gaaaaagtag
    21721 ctttaaaaac tttatcaaaa ctatcaaaga aaagattctt atatgttcaa gaaacaggca
    21781 agtgtatgta ttatacagtt gcaataaaag aaaaggcata tttagagttt atatcaagaa
    21841 atgtgcaaaa tcttttgaag aataatttta taaggaattt attagtatca tttcacgaag
    21901 aggagctaac agaggaaaag ataaagtcgt tagaaaactg ggtagtaaat tgggaagaag
    21961 cttatgtata aatgttatta tttttattac aatttagata attttggttt tgtaagctct
    22021 gcaactattt ttagatggtt gcagagttta tttttatttt ttattccctt aagcaatact
    22081 taaaagtaaa cgcatttata tttactaact tcaattactt ctaatactta aattactttt
    22141 taaaaatatt ttgatatgtc atctctatag taatctagaa cttgtttcta ttctttatat
    22201 aaagttttta tgaatgatat atataatatt cgttcatttg attaaaaata acaaaatatt
    22261 aaataattct actctgatag tttgttaaaa aaataataaa aaatattaat aaacaaaaaa
    22321 aaattatctt aagagaggag aatgttctaa aatataaaaa ggtttctaga tttcataaaa
    22381 gatactattt tagtcttgaa aatatttagt ttgaaaagat tttaatttaa tgattgatta
    22441 agttaaaaat gtgtatgtaa taaattttat tttatttatt gactaaatta taaagtttac
    22501 ataattattt aataattatg taattgttac ttgaaaattg atctatttta aaatctagtt
    22561 ataacttcaa aaaagactga aaa
//
LOCUS       DAEOTL010000065        22356 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEOTL010000065 DAEOTL010000000
VERSION     DAEOTL010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22356
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.065"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            278..1339
                     /locus_tag="KRH82_002781"
     CDS             278..1339
                     /locus_tag="KRH82_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBG8656051.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQSVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            1352..1549
                     /locus_tag="KRH82_002782"
     CDS             1352..1549
                     /locus_tag="KRH82_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBG8656052.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(1713..2417)
                     /locus_tag="KRH82_002783"
     CDS             complement(1713..2417)
                     /locus_tag="KRH82_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBG8656053.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            2582..3307
                     /locus_tag="KRH82_002784"
     CDS             2582..3307
                     /locus_tag="KRH82_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656054.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            3367..4959
                     /gene="hcp"
                     /locus_tag="KRH82_002785"
                     /gene_synonym="priS"
     CDS             3367..4959
                     /gene="hcp"
                     /locus_tag="KRH82_002785"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBG8656055.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            5330..6235
                     /locus_tag="KRH82_002786"
     CDS             5330..6235
                     /locus_tag="KRH82_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBG8656056.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFRLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            6359..7312
                     /gene="msrA"
                     /locus_tag="KRH82_002787"
     CDS             6359..7312
                     /gene="msrA"
                     /locus_tag="KRH82_002787"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBG8656057.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            7465..8595
                     /locus_tag="KRH82_002788"
     CDS             7465..8595
                     /locus_tag="KRH82_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656058.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(8712..9680)
                     /locus_tag="KRH82_002789"
     CDS             complement(8712..9680)
                     /locus_tag="KRH82_002789"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBG8656059.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            10015..10203
                     /locus_tag="KRH82_002790"
     CDS             10015..10203
                     /locus_tag="KRH82_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656060.1"
                     /translation="MNYHTKEELVEALRVISSSIINCEKGQKKFSEETSHHTCFKNII
                     EAIYISKSLIMDEISKRD"
     gene            10463..11662
                     /locus_tag="KRH82_002791"
     CDS             10463..11662
                     /locus_tag="KRH82_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBG8656061.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            11714..12217
                     /locus_tag="KRH82_002792"
     CDS             11714..12217
                     /locus_tag="KRH82_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656062.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            12324..12641
                     /locus_tag="KRH82_002793"
     CDS             12324..12641
                     /locus_tag="KRH82_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656063.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYSNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            12799..13758
                     /locus_tag="KRH82_002794"
     CDS             12799..13758
                     /locus_tag="KRH82_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBG8656064.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            13873..14658
                     /locus_tag="KRH82_002795"
     CDS             13873..14658
                     /locus_tag="KRH82_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656065.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            14950..16269
                     /locus_tag="KRH82_002796"
     CDS             14950..16269
                     /locus_tag="KRH82_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8656066.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(16344..16772)
                     /locus_tag="KRH82_002797"
     CDS             complement(16344..16772)
                     /locus_tag="KRH82_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656067.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTSTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(16863..18239)
                     /gene="hydG"
                     /locus_tag="KRH82_002798"
     CDS             complement(16863..18239)
                     /gene="hydG"
                     /locus_tag="KRH82_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBG8656068.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(18240..19325)
                     /gene="hydE"
                     /locus_tag="KRH82_002799"
     CDS             complement(18240..19325)
                     /gene="hydE"
                     /locus_tag="KRH82_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBG8656069.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(19361..20569)
                     /gene="hydF"
                     /locus_tag="KRH82_002800"
     CDS             complement(19361..20569)
                     /gene="hydF"
                     /locus_tag="KRH82_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBG8656070.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(20584..20835)
                     /locus_tag="KRH82_002801"
     CDS             complement(20584..20835)
                     /locus_tag="KRH82_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBG8656071.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(21216..22256)
                     /locus_tag="KRH82_002802"
     CDS             complement(21216..22256)
                     /locus_tag="KRH82_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBG8656072.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         8375 a         2676 c         3554 g         7751 t
ORIGIN      
        1 attatatata tttttttata ttgtttgttt tattaaaatt aatctagaaa aaaagtttta
       61 aaagcagaat tttattaata tttatatata gatatgaact attaataaaa cgttaaaaat
      121 acaaaaaaac tatagaaatt gacatatatt ccagtatttg ctaaagtagc tgttggggaa
      181 aattacaaaa attattaatg cgcattagat aatttacttt aattttttta gcatttgggg
      241 taatttataa tataaagcat tagaaaggaa aatataaatg agggactttt taaaaaatta
      301 taagtcatca attatacttt tagcatgtac tatagtaggg gcgatagtag gattagtact
      361 tggtccaaaa gcttcaatac taaaaccatt tggagattta ttcataaatg ctctattaat
      421 gatagtagta ccattagttt ttcttagtgt ttcttcaggt gttgctagta taaaaaatat
      481 ggaacgattt ggaaaaataa tgaagggtac agctatagta tttatgggaa caacacttgt
      541 aattgcattt ttaggtatta catctgcatt attatttaat ccgtctaaag gattagatgt
      601 atcaagtgta aaaaatttaa tggtggctca agatgcagaa actttagaat caaaaggaac
      661 gttattagac caagtagtat caagtattac agttaaaaat tttggagatt tattttccag
      721 tagtaattta ctacaatcag ttatatttgc agttttaatt ggaacagcaa tagctatgat
      781 gggagatagg ggaaatacaa taagaaagct tttatcagaa ggaacggaag caatattaaa
      841 agtagtaagt atattcatgc tttatgctcc tatagggcta ggctgttata cagctacaat
      901 aattggggaa cttggaagta aaataattca aggatatgta agggtgtttg taatttattc
      961 actaacagca gccatgtatt tcttattatt ttacagtctg tatgcttttt tatctgcagg
     1021 aaaacaaggg tttagacaat tctggagaaa tgctataaaa ccaatagcaa cggcactagc
     1081 tacttcttca agttcagcat gtataccatc aaatttagaa gctagtaaaa atataggagt
     1141 tcctgatgat atatcagaaa cagttatacc tcttggaata aatatacata aagatgggtc
     1201 agttttagca gtaataataa aagtggcatt tttatcaggt attttaggta gtggaatggc
     1261 aaatccagca acgataggtc aattatttat aactgtattt gttgttggag tatttatggc
     1321 tcctgtagca ggtggctgac ttattggtga gatgctcgtg gttagcatct tcggttttcc
     1381 agtggaggca attccactgt taacagttat aactactata actgatattc ctaatactat
     1441 attaaataca actggaaata cagtatcatc aatgttagtt tcaagattag tagaaggaaa
     1501 agattggctt atagataaaa cagcaattac tacaaagaaa ataagctaat tgtacactta
     1561 attaataaag ttaataggta tcttaatttt aataaattag atacctatta actttttaag
     1621 taaaaatata aatttaagat tcaaatatga tatttataat ttgaatcaac taatatagta
     1681 tatattgaaa taaatatgtt taaatatcta ttttattttt taaaataaaa gatttcaaat
     1741 ttatttttgt taaaagataa caagccttca tctcgcatct tgccaagctc tcttgacata
     1801 gaacttctgt caacacataa aaaatcagcc atttcatttc ttgaaaaggg aattgtaaac
     1861 tggtggctac ctgtttgttc tatctgtttt gaaaaataca taagcaattt ctcgcgagtt
     1921 gttttacgag aaagtaattc tattttattg tgaagtaaaa tgtttttttc agctattaat
     1981 tgtagcatat tttcaacaag cctattatga aatacacatg cagatgaaca aataccagtt
     2041 acacttttaa actttataaa taaaacttcg caagaagatg ttgtggttac tgtaacatta
     2101 cttttatgta gtctagtaca tgcgaatacc tctccaaata aatctccagg caagagttca
     2161 gctacaatat tcctattccc ttcgatatct tcctttatta tatgagcact tcctttaagc
     2221 ataattccaa tagaagtaac ttcacttcca acagagaata ttatactatc ttttgggtaa
     2281 gtcttatcta caacacctaa acattccaac atttcttcaa gttcatcact tttaattcct
     2341 tcaaatagag gaattttttt aagtaggtct atatgctttt ctaaaaattt tttcaaataa
     2401 tcacttcctt gttgcatatg caaccgataa tttgttttca ttgtactata ctaagtttat
     2461 aaaagcaagg ggatataaaa atcctactac aagaaatttg aaataaagaa atataggtat
     2521 taaaaataaa tatataagaa atcaatactt taaattaaaa aaattttatg aggtgatata
     2581 aatgatgaga aaaataatta aaattgatga ggaaaagtgt aatggttgtg gactatgtgt
     2641 tgaagcttgt catgaagaag ctataggaat ggtaaatgga aaagcaaaac ttttaagaga
     2701 tgactattgt gatgggctgg gagattgtct gccaacttgt ccaacaaatg cgatttcatt
     2761 tgagtataga gaagcagcag aatatgatga agctgcagta aaagcaaata tggaagcaaa
     2821 gaaagcacaa aagaaaactt tagcatgtgg atgtccaggt tctcagtcta agtcaataaa
     2881 tagagaggtt tcaaatagta cgtctataag caatgatata gtagagataa aaggttctca
     2941 acttaatcaa tggccagtac aaataaaatt agtaccaact aatgcatcat atttaaagaa
     3001 tgcaagtctt ttaatagcag cagactgtac agcgtatgca tatggaaatt ttcataataa
     3061 atttatgaaa aataaggtta cattaatcgg atgccctaaa cttgatgaag ttgactatgc
     3121 tgaaaaactt acagagattt taaaagaaaa tgatattaaa aatatagtag taacacgtat
     3181 ggaagttcct tgctgtggtg gtatagtaaa tgctgttaag acagctctac aaaatagtgg
     3241 aaaaatgata ccatggcaaa tagttactat atctgtagat ggaaaaattg tagatggaga
     3301 aatttaatta agtgaattat agaaaaatat aataaatttt aataaataaa aagggaggaa
     3361 taaaaaatgg aaaaaatgtt ttgttttcaa tgtgaacaaa cagcaggagg taaaggttgt
     3421 actataaatg gtgtctgtgg taaaaagggg ggtacagcta acttacaaga cgaacttaca
     3481 ggagtgttga ttggtctttc aagagcaact attggaaata agaatagacc aacaagtgaa
     3541 acagataaaa ttatgataga ggggctattc actactataa cgaatgtaag ttttgatgat
     3601 gaagctataa aaagacaaat tgaaaaaact gaggtagaaa aaagtaagct tgtacctaga
     3661 tgttcagatt gttcaacaac ttgtaataga aatgataact atgatatgaa ggatttatgg
     3721 aatgataatg aggacatacg ttcattaaaa tcattaatct tatttggatt aagaggtatg
     3781 gctgcctatg catatcatgc aatggtactt ggttatacag acaaagacgt aaatgaattt
     3841 ttctatgaag gattaatagc agttggagga gacttgtcta ttgacgaact tttaggtcta
     3901 gttatgaaaa ctggagaaat aaacttaaaa tgtatggaat tgcttgatag agcaaatact
     3961 gaaacttatg gaacaccaga accgactcag gtatctatga aaatcgagaa agggccattt
     4021 attgtagtta caggacatga cctttatgat ttacacaaat tattagaaca aacgaaagat
     4081 aagggtataa atatatatac tcatggtgag ttattaccag cacatgcata tccaaaacta
     4141 aaagaatata aacatctaaa aggtaatttt ggtacagcat ggcaaaacca gcaaaaagaa
     4201 tttgataata ttcctgctcc aatattattt acaacaaact gtttaatgcc tgttaaagat
     4261 agttatagag atagagtatt tactacagaa gtagttgctt atccaggtat ggttcatatt
     4321 gatgaagata aagatttttc tagtgtaata gaaaaagctc ttgaacttgg aggatataga
     4381 gaagatgttc atatgactgg tattaatgga ggagatacat taactactgg ttttgcaaga
     4441 ggtacagttt catctgtaca agataaagta gtagatgctg taaagagtgg agctataaga
     4501 cactttttat tggttggagg ttgtgatggt gcaaaacctg gaagaaatta ttacactgaa
     4561 tttgtaaaac aagctcctaa agacactgtt atattgacac ttgcatgtgg aaaatataga
     4621 tttaatgatt tagaccttgg ggatataggt ggcttacctc gtttaatgga tatgggacaa
     4681 tgtaatgatg cttatagtgc aattaaagtg gcagtttcat tggcaaatgc ttttgaatgt
     4741 ggagtaaatg atttgcctct tagcatggta ctgtcatggt atgagcagaa agctgtttgt
     4801 atacttctta cactacttca tttaggtatc aaaaatatct atatagggcc ttctttgcca
     4861 gcattcttat ctaagaatgt attagatata ttggttgata aatttgcatt gacacctata
     4921 tctactcctg aagaagatat gaagaagatt ttaggataaa taaatatatc tatacttaaa
     4981 gatatttata gttaaaatat ttttaagtat gccacaatta agataagggg ttaaacttaa
     5041 aatttgatta aaaaatcaat tttgagatga ccctttattt attttttgta ataattgaaa
     5101 aataaacctg ctttcagtat attcttttaa gaatttttgt attaaattta taatacttag
     5161 atatataata tcttatatat tttattttaa gtattaaagg tttgaatgta acttaaatat
     5221 taaaagagga acattgtaat atgtaacttg cataaaatat atatactata gtgaaattat
     5281 tttgattaaa atttaaaata taaggtgttt tatgtggggg tatatgtata tgaaaaattc
     5341 taattttaat atattggcat ttgatggtgg tggattaaaa ggggcattga gtatatccat
     5401 acttgagagg atagtaaaag agtatccaaa tctattaaac aatataaata tgtttggagg
     5461 tacatctaca gggagtctaa ttgcactagg gcttgcgtat ggtgtaagcc ctaaagagat
     5521 aaaagaactt tactcaattg aaaattcaaa gtatattttt aataaaagtt atgcagaaat
     5581 actcagacca aagtatgaaa acaaaaactt aaaagaagtt ttattaagta tatttccaga
     5641 ggaactagaa ttaaaagatt taaataaatt agtaatgata ccaagttttt atataggaaa
     5701 tgaggaaaat gcatggaaac cagtatttta taacaatatg ccaaattctt ttacaaagac
     5761 tagcaaagtt gtagatgtag caatggcaag tagtgctgct ccggtatttt ttccaacata
     5821 taatcgtcat gttgatggag gaataatagc aactgacccg agtttagcgt gtataattca
     5881 tgccattgat agtggattta gacttaagaa tacaagactt ttttcaatag ggactggata
     5941 tgtatataac agtataaagg cagatactac cgaatgggga gctattgact ggataattaa
     6001 taaagaacct gatttaccaa ttatatctat taccttagaa ggaaattctc aaatgagtca
     6061 gttattttct caaaaacttc ttggagataa ttactataga ttaaatccta agatggaaaa
     6121 agatgtagct atggatgatt gtgatgcatt agaatatcta atgtctttag gagaaaattg
     6181 tgatataaaa gatgcttttg gatggataaa gaaaaagagc ttttatagaa attagattca
     6241 atttgcaatt gtatttttac acatgatttc attgagtagg taaaaataat aaaatgcaga
     6301 ttattaagtt acttcttagg gaataaataa agtataattt atttaaggag tgatgaaaat
     6361 gataaaactt gctacttttg caggtggatg tttttggtgt atggtaaaac cttttgataa
     6421 gtatgatgga gttattaaag tagtttctgg atatacaggt ggtcatgttg aaaaccctac
     6481 atatcaagag gtatgttcag gaactactgg tcatttagaa gcaattcaaa taacatatga
     6541 tgatgatata ataagttatg atgaacttct aaatatcttc tggaaacaga ttaatcctac
     6601 agatgatggt ggacaatttg gtgatagggg aactcaatat aagactgcta tattttatca
     6661 tgatgaagaa caaaaaaata tagctttaga gtcaagagaa catctggaaa atagtaaaat
     6721 atttgatagt aaaatagtga ctgatataat tccagcaact aaattctacg aagcagaaga
     6781 aaatcatcag gattattata aaaaaagacc attaaactac aatatgtatt ataaagggtc
     6841 tggaagatat aattttgtaa aaagtcattg ggatggaaac aatataaata gggaagagtt
     6901 aaaaaagact ttaactccta tacaatttga agttactcaa aatgatatga cagaagtacc
     6961 ttttgaaaat gaatattatg ataataacaa agagggaatt tatgttgata ttgtaagtgg
     7021 agaagtgtta ttttcttcaa aagataaatt tgattctgga tgtgggtggc caagtttttc
     7081 aaagccagtt atagataaat ctatcattga gagaagtgat ttctcacaag gtatgtacag
     7141 agttgaagta agaagtgcta aaggaaattc tcatttaggt catgtatttg atgatggtcc
     7201 aaaagaactt ggaggtttaa gatattgtat aaattctgct tctcttaaat ttataccaag
     7261 agaaaatatg gaagctttag gatatggaga atatttaaaa ctttttgagt aattaggaat
     7321 atttattata aacttatcta aaaggtgaaa atataaaaaa atattttcac cttttgtttt
     7381 tttgtcaata gtatgataaa ttattaattg taatcttatt tataccaata gattaagaat
     7441 ttaattttga aagagagaaa acaaatgaat ttaaaagact ttaatggaaa gagattaaaa
     7501 tcagctagaa tttttagagc aaagacgata gaacagttgt ctaaagaaac taaaataaat
     7561 aaaaaagatt taaaagcttt tgaggaaaat aagtatgtac caaatataga aaatacatta
     7621 aaattatcta atatattaaa ttttccaaaa gagtattttt ataaaaatga aaatataaat
     7681 atcgttgtag aggatagcca ctttaaccct caatctaaac tacctagagt agaagagatt
     7741 tcttatagag aaaaaataat tataatacat aaaatatatt catttatgga gaattatatt
     7801 aagtttccaa aagaaaactt gccaaataga aaagtaatgt cagatattaa tataaatgat
     7861 atagaatctc ttgcatataa gactagagag ttttgggatt taaatagtac tccaatagta
     7921 aatatggtaa gtttgttaga gtctaaaggg attataatat caggtatgaa tgtagataga
     7981 aaaggggcaa ctatctttac tcaaaaacag agaattagta aagaatctaa atatctaata
     8041 tctctgggta atgacaaaaa gtcagcatca attagaaatt atactttggc atgtgagctt
     8101 ggatatataa tatcaagtga attaagaata ccaagtaagc aattttcaga agatgagtat
     8161 gcctgtgcat ttttattgcc aaaagagagt tttttaaaag atttgactca tccagaagat
     8221 ttagattatt atgtagaact aaagaaaaaa tggattgtac ctatatctgc tatgattttt
     8281 agagcatata atctagaaaa gataaattac aaaaaataca attatcttat gaatgaaatg
     8341 gataaaaaag gctggttgat agaagaacca ctagacaaaa tgaaaggttc aagcccaacg
     8401 tatttaaaaa gagcagttga attattgata gaaaataaaa taatgagtgt aaatagtata
     8461 gtatcaagtt tagaggaatt tggaataaat ctttatccag aagacttaga attattgatg
     8521 ggattgaaaa aaggattgtt atctcaagag gtaaataaaa aaagtaaagt tataaaattt
     8581 gatggtaaaa aataggttta tattttagta ttaaaattaa aagcaggtac aaatgattta
     8641 aacattaact tagttaaaag tcttttcaat aagtcattta cctgctttta gtgtaagaaa
     8701 gaatattgaa tctaaagtgt ttttgaaagt gcaatatatt cccttaaaac agaacaagat
     8761 ttattaaatt cgttttgctc atattcagtc atattgattt caataatttc ttcaatacca
     8821 tcttttccta taacacatgg aacacctgca aatacatttc tttcgttata ttgaccttct
     8881 agtaatgtag aaactggaag aacttttttc tcattgtgta gtatagcttt tacaatttct
     8941 actaaagcag tacctatacc aaattctgta caatctttac catttattat acttattcct
     9001 gtttttttat ttttttcaac tattgatggt aagtctaaat tgctataagt acttgggttg
     9061 tcttttatca tgtctaagat tggtttacca ccaattgaaa catgagacca aggaaccatt
     9121 tgagaatctc catgttcacc catagaataa gcttgaattg attgttgagc gattccagtt
     9181 tcttcagata aaatccttct aagtcttgtt gaatctaaag ctgttccagt tccaatgact
     9241 ttgtttttag gaaagccaga tttttcccaa atataatttg taactacatc aacaggatta
     9301 gatatgacta caaatatacc atcaaagcca gaatcaacta tgggttttac tatagatttt
     9361 atcattccaa tagttggtct tagtaaatct aatctagttg tgttttgtct acgtaaaggc
     9421 ccttctgaag agtctgcaac acttatcact actatgtcag aatctttaca gtcagaaaaa
     9481 gttccttttt ctatatgtac tttatgtggc agatatgaaa ctgcatcagc taaatctaaa
     9541 gcttgagctt ttgatttaga ttcatctata tcaatcataa agagttcatc acaaactcct
     9601 tgagttatta aactaaatcc acaatgagaa ccaacatgcc ctgaacctac aatagatatt
     9661 tttcttggct ttattgccat tttaaatcac tccccctaaa ataacgatac attgaaaatt
     9721 atagatgtta ttaaaagctg tttttgaata ttttaatatt ctattatttc agaaaattta
     9781 tttaatatga ttttatacta aaatttttaa aaaagcaatg ttaatatact ctctattagt
     9841 gaatattaaa gtattatatg tatattaata attattaaaa tatgtaatgt cactgatagt
     9901 tagaatattt aagtgataaa agatgtgtat aaataataat gatgtcagtt tataatgata
     9961 ttaaattgag gtatactgtt tctctaaatt aaaaaataaa ggagtaaatg tgttatgaat
    10021 tatcatacaa aagaagaatt ggtggaagca ctgagagtaa tatcttcaag tattattaat
    10081 tgtgaaaaag gacagaagaa attttctgag gagacatctc atcatacatg ttttaagaat
    10141 attatagaag caatatatat ttcaaaatca ttaataatgg atgaaattag taaaagagat
    10201 tgaagcttat tttgcaattt aacatgtttt aatatacatt ttattatata agaaaataag
    10261 taaatataca tgttataaaa tattggaata atatacaatt ataaatttgt taacattaat
    10321 atctatatgt taaaatatag tagaagatgt tagtaaataa taggatgagt tctattttaa
    10381 tacaattaaa ttaagcttag tttgaaattt gtatctaaaa agtaaagtaa tctagaatta
    10441 agaaaatgga gatagaatta taatggaaaa attatattat acaaatcagt atataagaga
    10501 ttttacagca gaaataattg aaataaaaga agtagaaaat aagtatcatg ttttattaga
    10561 taagacagct ttttttcctg gtggaggagg tcagtttgga gacctgggaa aaatagagaa
    10621 tgatgatgta ataaatgtgt atgaagatgg aaaaaaaata taccatgtat tagataaaaa
    10681 acctataaag atacataagg taaagtgtag tattgattgg gatagaagag aagatggaat
    10741 gcatcaacat tttggacaac atgtattgtc tggatgtttt tttaaaactt ttaatgcaaa
    10801 tacgacaggt tttcatttgg gaaatgagta tagtacagta gatatagaag gtaatttaga
    10861 agaggataaa attagagaga tagagttgtt tgccaatgaa attattcgtc aaaatataca
    10921 agtagagaca ttacttccaa cgaaaaaaga actaaaaaag atttggttaa gacgtgattt
    10981 gccaaatact gatgaagaga taagagtaat aaaaataggt gatttagata cgaatgcatg
    11041 ttgtggagtg catccaaaat caactggtga attgagaatg ataaaaataa agaaatggga
    11101 aaaacataag tcaagtacaa gaatagagtt tctagcaggt aaaagggcag tggatgaagt
    11161 attgaagagg gatatatatt tgactaaaat atgtagatat ttaagctgta gtgaggaaga
    11221 tgctataaat ggtattgtaa atctaaatag taaagtggaa gaggctttaa ttaaaaaaag
    11281 aaggcttgaa gaagtagtat ctacatatca ggtcaaagaa atgattgaaa aagcaaataa
    11341 ggttggcaat atttcggtca ttaaaaaaat ttatgatgat gaagatttga aatatgtaaa
    11401 taagatagca aataaaattg cagaatatga aaatagtatt gcattattag ctgttaaatt
    11461 taatgataaa ataaatttag tttttgcatg ttctaaaaat ttaaaagata ttaatatggg
    11521 agttttatta aaggatgcaa taaatcttat agatggcaag ggtggtggaa gtaaagtatt
    11581 agctcaagga ggaggtaaga ataatggaaa tttagaggct acacttgatt atgcatttat
    11641 gaagatagaa aaaactctat aaatatatta tataaaaaac cttagtagat aaaatagata
    11701 tggaggaata agtatggagc aacaaaagga ctacatagag ttatatgaaa atgaagaact
    11761 aatagagata agagaagcac gtatggatga tttggataca atagcaaaat ttaattataa
    11821 tttggctaaa gaaactgaag gaaaagaact tgatatggat gttttaacta aaggtgtaaa
    11881 agcattgtta ttagatgaga gaaaaggaaa atatcatgta tatacagtat ttgataaagt
    11941 tgttgcacag attatgtata catatgagtg gagtgattgg agaaatggaa atttcctttg
    12001 gattcagagt gtatatgtag ataaggaata tagaagaaaa ggtatcttta attatttatt
    12061 taattatata aaaaatatat gtgataaaga tgaaaatata gttggaatga gattatatgt
    12121 agaaaaagaa aacataaatg caaaagcaac atatgagtct ttaaatatgt atgagtgtga
    12181 ttataatatg tatgaatacg aagtaataca ttcgtaatat aaatttgtaa tactgttata
    12241 ctgatgttat aaagtattga ttatattgac gattatatga aataaactgg atattataat
    12301 tagaattttt agggggtata aaaatgggcg ttttaaaagg aatgttttat gtatttttat
    12361 ttttagattt agtgtcaata ttctgtttct tttttaataa aggaaaaata gcatctaata
    12421 aaattgtgtt taatgcaata ggagtactta catttgtact ttgttttatg ctttttagtt
    12481 attattctaa taataatctt attggaaaat ttattgcttc tctatttttt atatttggag
    12541 ttgcaggagt tatgttgaaa gaaaaaaatt ttttatatgc tagacttctt ttaactgtag
    12601 ttatagtttt ttctacatta agattgttcg ttattcaata aaatgtattt gtatgaaaat
    12661 ttattaaagt ctacacattt aagtgtaggc ttttttgatt ttttgtttga aaattaagga
    12721 aattttaagg aaattttaaa atcgtcttaa atatttattg atatacttaa aatattaata
    12781 gcgaaaggag acttatcagt gatagaaagt aaaaagtcag aaaaattgtt actgtcaatt
    12841 atatacataa tatttttggt atatatttta atgattataa gaataatttt atttagagat
    12901 gtaccaattt acgctatttt caagggaacg tttaggaatg taaatttaat tccattttat
    12961 acaatatatc aatttatagt agatagtaat cttgacttta tgaaagctac tgtaaatatt
    13021 atagaaaata taggtatatt tattcctatg ggaatttttt tacctatagt atgtaaaaat
    13081 ctaaataaaa aaactataat tatagtaatt atacttgtta gcctagcatt tgaattaaca
    13141 caatatattt ttgctcttgg aagtagtgat atagatgatg ttattttaaa ttcattaggt
    13201 ggcataattg gaattaatat ttacataaac atgaataaat tatttcccaa tgatattaac
    13261 agatttaagg ctataatagg tactagttta gttttaggag ttataggatt aggagttatt
    13321 tctaaaaatt atcataactt actaactttt aaatttagac ctgatagaaa aatatcaaaa
    13381 atattaattg aagaaaatag ggaaataatt aaagatataa ataaagatac agtagatata
    13441 gttgggacat ttgagagctt taaaaaagga ataataacta ttaaagcagg ttctaataac
    13501 aaagtaaaga gaccagagaa tttaattgat tctgatggaa atataagaat ttatttaaat
    13561 gaaaatacaa aattagtatc ttatataatt accaaagaat caaaaatgga tatagttaaa
    13621 tatgaggaat ttgatgtgaa gaatttagat ttattaagga gatatgatac tattaatgtt
    13681 tggattgata aagaaaatca gccaaaggat aaacatggta ttatggctag taaattatta
    13741 attggattgt atgaataaaa tattaaacaa gaataaaaga ataacaaata taaaaaacga
    13801 aaaaactatt tctataatta tttttacgtt gtgcataaaa taagaacatt agtgaaggag
    13861 tagagataaa ttatggagat aataaaatat atcttgtact tttttatata ttcattttta
    13921 ggatggacag tagaaagtat aggatgttct atagcaagca aaagaataat caacagaggt
    13981 tttttaaatg gtccaatatg ccctgtttat ggttttggag cggtaattgt gatatcacta
    14041 ttgggaagat ttaataatgt agtaatagta tttctattag gaatgatttt aactacgata
    14101 ctagaatatt ttacaggatt tattttagaa accttatttc atgctaaatg gtgggattat
    14161 tctgacagaa aattcaatat aaagggtaga gtatgtttaa aaaatgcaat atactttggt
    14221 gtaatgtctg ttttaataat aagatttata catccattta taaaatattt tgtaagtata
    14281 attccatata gaatattaat ttcaatggct ataattacaa cactttggac tatacttgat
    14341 ttgattgtta ctattataac acttaaaaaa ttagatataa agttaaactt attagacgat
    14401 ataattacag accttaatga tataaatgtg aaattggata aatttgatag aggagaaata
    14461 caagctttat ttaaaacaat aaataacgac gaattagaag ttagagaaaa aataaacaaa
    14521 ataaatagta agttggaccg tatagagtct aatattattt tacaaaaaag agttataaaa
    14581 gcttttccac atataaaaca taaaaaacaa caagagcaac tagaacattt taaaaaaatt
    14641 attaatgaga aaaggtaatt atacaattta atgaagacga atagaataat ggtatttata
    14701 agatgatttt cagaggactc tataaaaata gaatagagtc ctttattttt tgaaaaataa
    14761 tgtttatttg ataaaaataa aatatattgt ttctgaataa caaatatttt gaaaattata
    14821 aaaacatata ttgacaattt gtgtcaaaaa tactaacatt aagtatataa agaattttat
    14881 atgagaatat ctttataaat cgcaataatt ttaaaacata aatttattta aagaggggat
    14941 gatttgccaa tgagcgagat aactagtcaa atgataagta cagaagaaaa aaaatatgtt
    15001 gctaaaactc aaaagatacc ttattatcca gtagcattta aatcaggtga tggtgcaatg
    15061 ctatatgatt atgaaggtaa tgaatatgta gattttttag caagtgcagg ctctgcaaat
    15121 gtaggtcatg gtaataagga aatctcacaa gcagttaaag aacaaatgga tgatataaca
    15181 caatatacac ttgcatattt ccatagtgat cctcctgtaa aattagctga gaagcttgtg
    15241 gaaatagccc ctggagataa tgataaaaaa gtactataca gtgcaactgg ttctgcttgt
    15301 atagatgctg ctataaaatt agcaagaggg tatactggaa gaacaaagat aatatctatg
    15361 tgtgaatctt atcatggaag tacttatgga gctatatcta tatctgcttt aagtacaaat
    15421 atgagaagaa aaatgggtcc attgttacca gaagtttatc acttccatta tcctgataaa
    15481 aatagaacag ctaaagaatg tttagatgag atagaatatg cttttgcaca ctatctacca
    15541 gcagaagagg tagctgcaat atttatagag ccaattgcag gagatgcagg aataatagtg
    15601 cctccagtag agtgggtaca aggtttaagt aaaatatgta aagaaaatgg aatattactt
    15661 gtaagtgatg aaatacaaca aggtatggga agaacaggta agtggtttgg tatagaaaat
    15721 tttggtgttg aagcagacct tatagttctt ggaaaatctg ttggaggtgg attacctcta
    15781 ggagcagttg ttggaagaac agaaataatg caaagtcttg atgcaccagc acatttattt
    15841 actttagctg gaaacacaac agtatgtgtg gctgctttaa aatctataga gataattgaa
    15901 aaagaaaact tacttcaaaa gagtatagaa atgggagatt atattaaagc aggatttgaa
    15961 aaactaaaag aaaaatacga tataattgga gaaataagag gcataggatt atctatagga
    16021 gttgatatag ttaaaggaaa aggttctaat gaaaaacatc cagatgctac agctaagata
    16081 tgttatagat gtatacaaac tggattaata atgatattct taggacaatc tactttaaga
    16141 gtgcaaccac ctctagtaat aactaaggag caagtagata aagcaatgaa tatcatagat
    16201 tctgcaatag atgattattt aaatggtaga attggtgatg aagtatatga agtaactcaa
    16261 ggttggtaaa ataaatatta aatgaaaata ggagttatct caattttaga aaattatttc
    16321 tgaaaagaga taactctttt aagttaccca caaataagaa aattgtttga ttcattaaag
    16381 actatatttc ggatgtcgtt tttgtgagta tcagagacag tattacgaga ataattacct
    16441 ttattcgtac tatctgttaa tttagttata attaagatag ctaaaagaat aagaattact
    16501 gtgtataaag caataacata tggttttctt ttatatttgt atttgttatt gaaaaaagaa
    16561 tggccataat tatttttatt tactttagat gtacttgtat tctttttctt gttacctttc
    16621 tttttatcat ccttttttct atttttaggg taaggaatga ctttgtgtgt attatcaagt
    16681 ttgatatttt tatttttttg aatattgttt tccaggctag cctttttttc tccaaattga
    16741 atagttttat tggtattgtt gttatctttc aatgttaatc tccctccctt aaactttccc
    16801 tttagataat attactacta acctatggaa tatacaataa ataatatata agtaataaaa
    16861 ttttataggt ataaatctct ttctccacgc tctaaggcag tcatattgtt agatactatg
    16921 tttcttatat cttctctttc tatcttacct atttcttctg cgataagttt tttacccata
    16981 attttaagtt cttcatctcc ataatcgatt aaaaattcat ttaatgtagt aagagcattt
    17041 ggtgtacata cattatggat ttgtcgactt ttagctaagc tcatgaatct atcgccagtt
    17101 ctacctttac gataacaagc tgtacaataa ctaggtatat atccatcagt aatcagttct
    17161 ttaagcacct caacagggct tctatggtct ccaacttcaa attgttctgt attgtcacca
    17221 tcttcatatg ctttatatcc tccaacacct gttagagaac ctgcactaat ttgtgataca
    17281 ccatatttta gtaactcatt tctcatttca gcagtttctc tagtggacat tatgattcca
    17341 gtaaaaggaa cagccaatct agttatagct actatttttt tgaacatatc gtcagaaact
    17401 aagtgaggaa aatcttctaa gctcatacct tcagcttttt tcaatctagg gaaagatata
    17461 gtatggaaac ctacaccaaa tttttcctct aagtgttcgt tgtgcatcat aagtcctaga
    17521 acttcaaatt tagggtcaga taaaccaaat aaaactcctg caccaacatc atcaacacca
    17581 gcttccatag ctctatcaaa agctgttaaa tggtaataat agtcattttt tatagattga
    17641 ccatgcattt ttataaatgt tggtttgtga taagtttctt ggaataatat ataagttcct
    17701 attccttttt cttttagtaa tttatactca tctacacttg tagctgctat gttaacgttt
    17761 acccttctta tatttccgtt ttcattatat gttgaataaa ttgcatctaa gcaatctaag
    17821 atgtaattta tatcacaatt tttagggtct tcaccagctt ctagagcaag tcttttatga
    17881 cccatttttt ctaatatttt aacctcttcc tttatctctt ccatggtaag tttttttctt
    17941 ttaaatttgt tgcatttact aaaaccgcaa taaacacatt catttacaca gtagtttgat
    18001 acataaagag gggcaaataa aaccactcta ttaccatata tttcattttt tatttgccca
    18061 gctatactaa ataatctatc tagttgtttt ttatcttcta cttcaagaag tgtagctata
    18121 tctttataac taagtttttc ccttctatca gccttatcaa gtaccttttc aatatcatca
    18181 gaagttgaat tttttgcatc ttctaataaa gaattaataa gttcatggtt tatgaacatt
    18241 tacaaacgcc tccattcaat attatcaccg cgagaatagt caacttcaag tcctaatgac
    18301 ttgatgtttt cttctaaact ttggtgatat tcacaagctt cttgaccagt aaaggctttg
    18361 ttatcgtaaa gagaatattg ttttctaaat tcttgaggag aaaggtttgg cataattaca
    18421 ttgcaaccag ctaaaagacc tgcatttcta ccactagggt ttatagatgc caaggctgtt
    18481 gtagcgggta ataaaacttt tggaagtaga agtcttgtaa ttgaaagcat aagtaatgtc
    18541 ttctctaaat ctccatgttt ataatcctta aaaattgtat catggtgtgg aataaaaggt
    18601 cctattccaa ccatatgagg atttaactct tttaggtata ataaatcacg aacaaggtct
    18661 tcgttgttct gaaatggtga ttcaaccata aatccagcac ctacctgata accaatttct
    18721 ttaaggtttt ttaggcattc ttttctagtt ctaagctcaa tgtttggcgg atgtaatttt
    18781 ttataatgac tgtctgtagc agtttcatgt cttaaaagat atctatctgc accacataaa
    18841 aagtattttt tatacgaatc ataactcttt tctcctagtg atagagttat ggcacaatcc
    18901 tcatatttat tttttatact tgaaacaatt tcacatattt tatcatcagt aaaatatgca
    18961 tcttcaccac cttgcaaaac gaatgttctg tatcctattt tataacctat atcacaacat
    19021 tcaagtattt catcaagtga aagcctgtat cttatgatat ttttattaga agattgtatt
    19081 ccacaatagt agcaattatt tttacaatag tttgtaagct ctataagtcc tctcaagtag
    19141 actctatttc cataatgttt atttctcatg tcgctagctt gtttataaag atagtttctt
    19201 aaattttgtt cgaagttata ttcctcattg tcgatatttt ctattaaata tagtagttca
    19261 tcaaaactta atgaattaat gctgtaaagt ttatctataa agtatttaat cttattttta
    19321 gtcatattca aatatgtaat tattaagtat agttaaattt ttaataattg aaaagttcaa
    19381 gtgatctttc caaaatacct tttacatatg ctattaagac accatagttt acaataggta
    19441 cattgaaaga ttttgccttt tctattctag ataacattcc agctctattc atcatacaag
    19501 ctccacagtg aactacaagg gcatatttat ttatatcttc agtgaaggat actccagaac
    19561 taaattcaaa agtaatgttt ttgccagttt tctttctaat catattagga atttttactg
    19621 ttccaatatc atcagtttgt ctatgatggg tacatccttc ggccatcaag attttatcac
    19681 catcttttaa attttctaaa gcataagctc cattaatcaa ttctttaagg tctccctttt
    19741 gtctagcaaa caatatagaa aaagatgtaa gaggaatatc ttttggtgta tctttatcta
    19801 cttgtggaaa tacttgagag tcagtaataa caagttttgg ttttttgcct aaattagata
    19861 gagtttcttt taaactatct tcttttgtaa ctatagaaat tgcaccatta tccaaaatat
    19921 ctcttataac ttgctgttga ggaagtataa gtctaccttt tggagctgct ttatctattg
    19981 gaacaactaa aacaactaaa tcatttggtt caattaaatc tgataccaat ttgaactcag
    20041 tgctatcctt aggcaaaact tttattattt cattttttaa attttcaatt ccaattttat
    20101 ctgttgatga gacagaaaca actggacatt taactttatt tttagttaag tttaaaattt
    20161 ctgattgatt cttaatagta tcaattttgt taagaattag aatatgaggg atattcttat
    20221 cattaaattt ttcaattagt gacaaatctt cttgtgatat accaatttgg caatccacta
    20281 ctagtaaagc tatatctgtc ttttctaaaa catctagtga tttacctatt ctaagttcac
    20341 caagttcacc aacatcatca agaccagcag tatctataag aacacaaggt cctataggaa
    20401 ggatttccat tggtctaaat actgggtctg tagtagttcc agcaatatct gagactattg
    20461 cagcactttg atttgttata gcatttatta tgctagattt acctgcattt cttttaccaa
    20521 agagacctat atgtactctt accgattgtg gagtagaatt tagactcatt tgtactcacc
    20581 accttaaact tctttttttg atatactagt ttttacagat acatgaggta tgttgcccaa
    20641 tttaccagtc aaactattaa tagtatccat ttcgccaaca actgctatac atacgattga
    20701 gacaccttct tcttcgcaag gaatgcccat tcttccttta ataatacctt taaaacctga
    20761 tacaacctca ttgaatttaa attgacattc ttttggctct tccaaaatag cacttataac
    20821 tgcaaccttt ttcataaata tcctcctaac tcagaaaata tgtcttaaac aaatccaaaa
    20881 tcaaaaaact tttctttgta aagaaaagtt tctacaaaag aaaagttatt aattacacaa
    20941 gtataatgtg ctatattaaa ctatttcctt acagattaga taactctttt ctggtagggt
    21001 tagcttgtaa aaatttaatt taacaacaag taactgaaga aaatttttat acaatttata
    21061 taaattataa taaaaattaa ctaaagaaaa ttgaagttac ttatataata gtagtaaatt
    21121 gaaattaagt ctatagaaaa accaattttt gtataaaaat aaaaattaaa gttaattatt
    21181 tgttaagaat tgactttggt aaaatatata attaattatt ctttaagcat ataatttata
    21241 agtaatttta gtgtattttc aatagcttct atatgtgttc tttcataatg gtgactattg
    21301 tttgttccag gaccaacaca tgctatttga acatcttctc cccaacgaat agcttctgaa
    21361 gcatctgaac catagaaagt aaatacatcg acagcgtagt ctaaattatt gtcttctgca
    21421 acatcgacaa gcttgtttct taaattaaaa tcatataatg ataaattatc ttttgcaact
    21481 atagttacac catgttcact agatgtttga cttggtccag taggtgctat atctattgct
    21541 acaaattctt ttgttttttc aggtaaacat ttagaaacac catgtccaat ttcttcataa
    21601 ttacttatat aaaagttagt agtatgctta ggtgttaaat tgttttcttt aaaatatcta
    21661 catatttcaa gaaccattgc tacagctgat ttattatcta tatatctaga ttttataaaa
    21721 ccagattctg tagcctcaaa tctatggtct aggcatacaa aatccccaac acttattcct
    21781 aaatctaata catcttgctt tgtaaatact ttttcatcaa gtctaataat cattgtttct
    21841 tcatttcttt cagtggcagc ttttgtttga ccatatatat gagtagaagc atacttaaat
    21901 acaacacttc ctctgatttt tttacctttt ctagttataa cagtacagtt ttctccctct
    21961 atagctgccc aacatccacc accaacttta tggtatttaa gagtaccatc agatgatatt
    22021 tcttttacta tagctccaag tgtatccata tgtgcagata ttgttatttg atttgaatca
    22081 tcttcaccag gaagagtagc tataagtgca cctttttttg taagaatagt gtcaagacct
    22141 aaattttcaa aatctttttt gatttctaaa actgcatttt cagtatatcc agctgggctt
    22201 ggaatgtcca aatatttttt cattaaattt atagtattag ttaaatttaa attcatattg
    22261 tttcctccta aataaatata tttatacaaa ttataacata aatacaaatg ttctgaaaac
    22321 taaaattaaa agaatagaat ctaaacatat ttaaaa
//
LOCUS       DAEOTL010000066        22289 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEOTL010000066 DAEOTL010000000
VERSION     DAEOTL010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22289
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.066"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            305..763
                     /locus_tag="KRH82_002803"
     CDS             305..763
                     /locus_tag="KRH82_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8656073.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFEEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            824..1099
                     /locus_tag="KRH82_002804"
     CDS             824..1099
                     /locus_tag="KRH82_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656074.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1158..2432
                     /locus_tag="KRH82_002805"
     CDS             1158..2432
                     /locus_tag="KRH82_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBG8656075.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2562..3614
                     /locus_tag="KRH82_002806"
     CDS             2562..3614
                     /locus_tag="KRH82_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBG8656076.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DNHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3614..4645
                     /locus_tag="KRH82_002807"
     CDS             3614..4645
                     /locus_tag="KRH82_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBG8656077.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     KESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4737..5549
                     /locus_tag="KRH82_002808"
     CDS             4737..5549
                     /locus_tag="KRH82_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBG8656078.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5552..6472
                     /locus_tag="KRH82_002809"
     CDS             5552..6472
                     /locus_tag="KRH82_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBG8656079.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6647..7093
                     /gene="rpiB"
                     /locus_tag="KRH82_002810"
     CDS             6647..7093
                     /gene="rpiB"
                     /locus_tag="KRH82_002810"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBG8656080.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7123..7788
                     /locus_tag="KRH82_002811"
     CDS             7123..7788
                     /locus_tag="KRH82_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBG8656081.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7898..9400
                     /locus_tag="KRH82_002812"
     CDS             7898..9400
                     /locus_tag="KRH82_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBG8656082.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRTYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9712..11301)
                     /locus_tag="KRH82_002813"
     CDS             complement(9712..11301)
                     /locus_tag="KRH82_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8656083.1"
                     /translation="MVTKLKNLIINDSKAKFILLLLLFLLVSILFEAVYDLNNNFSNI
                     NYYYREFALPHFYFFGTPVHLSKVELEFVCIGIILSSFLLTILCFTLYKKNKQTKVKF
                     LENVINLFSKVKIELTLILTLILLTLRFHAFTSNKMFYNTNLIIYNFIIISIVYIIYE
                     NIKYNNYNLKDMSITYVFFSNLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFM
                     YIYYAEAIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVI
                     GDDEISTLAKSINNITGGLETAVDANIKNEMMKAELITNVSHDLKTPLTSILSYVDML
                     KNNDFDRETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQS
                     IVEFEDKIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDM
                     FIKEENIILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENA
                     HMEIIIDADLFKVMLTFRRVN"
     gene            complement(11270..11986)
                     /locus_tag="KRH82_002814"
     CDS             complement(11270..11986)
                     /locus_tag="KRH82_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656084.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
     gene            complement(12525..13325)
                     /locus_tag="KRH82_002815"
     CDS             complement(12525..13325)
                     /locus_tag="KRH82_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBG8656085.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            complement(13639..14370)
                     /locus_tag="KRH82_002816"
     CDS             complement(13639..14370)
                     /locus_tag="KRH82_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656086.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            complement(14357..15052)
                     /locus_tag="KRH82_002817"
     CDS             complement(14357..15052)
                     /locus_tag="KRH82_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8656087.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            complement(15054..15845)
                     /locus_tag="KRH82_002818"
     CDS             complement(15054..15845)
                     /locus_tag="KRH82_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656088.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            complement(15855..16667)
                     /gene="modA"
                     /locus_tag="KRH82_002819"
     CDS             complement(15855..16667)
                     /gene="modA"
                     /locus_tag="KRH82_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8656089.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            complement(17302..17502)
                     /locus_tag="KRH82_002820"
     CDS             complement(17302..17502)
                     /locus_tag="KRH82_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBG8656090.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(17727..17903)
                     /locus_tag="KRH82_002821"
     CDS             complement(17727..17903)
                     /locus_tag="KRH82_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656091.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(17957..18046)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(18226..18426)
                     /locus_tag="KRH82_002822"
     CDS             complement(18226..18426)
                     /locus_tag="KRH82_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656092.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(18428..18778)
                     /locus_tag="KRH82_002823"
     CDS             complement(18428..18778)
                     /locus_tag="KRH82_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBG8656093.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            18940..19129
                     /locus_tag="KRH82_002824"
                     /pseudo
     CDS             18940..19129
                     /locus_tag="KRH82_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(19606..19776)
                     /locus_tag="KRH82_002825"
     CDS             complement(19606..19776)
                     /locus_tag="KRH82_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656094.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(20165..20653)
                     /locus_tag="KRH82_002826"
     CDS             complement(20165..20653)
                     /locus_tag="KRH82_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBG8656095.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSITIPNDKNMIITFLSNKS
                     DN"
     gene            21457..21831
                     /locus_tag="KRH82_002827"
     CDS             21457..21831
                     /locus_tag="KRH82_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8656096.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            21936..22289
                     /locus_tag="KRH82_002828"
                     /pseudo
     CDS             21936..22289
                     /locus_tag="KRH82_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         8610 a         2716 c         3329 g         7634 t
ORIGIN      
        1 tataaaatag ttgttaaaca taaaaaacca tttgtaaaaa acaaaaaaat catttctcta
       61 acaaaaaaaa ccacaaaaaa tataaaaaag tatggctagt taagtgatta acaagtaaaa
      121 attaaaataa aaatcaaaaa aaatttatca atgaaagtca gctaaaatcc tggaagagag
      181 cattattttt gggaaaacat tttcttttgt ttcacaaaaa aagccacttt ttggcacaca
      241 acatgcttta tataaagtca agaaaaacta aggtataaga caaaggcaat taggaggtgt
      301 aaatatggag tttataaatt ttgtaagtga taaagttata gaccttaaaa tggattgtaa
      361 aacgaaagaa gatttctttg aagaaataca taataaagtt tttgatttag gctttgtaaa
      421 agaagaattt ggagaaaaaa tattagcaag agaaaatgta tttccaacag gtttaaattt
      481 aggagattat ggagtagcaa taccacatac agatgcagaa tatattaaag agcaatttat
      541 atcagtctgt acttttaatg aaccagtagt gtttagttct atggaagacc aagatgaaaa
      601 agtacctgta aatttggctt tcgtattagg acttaatcaa ccacacagtc aattatctgt
      661 attaacagaa ttaatgggaa ttatgcaaaa taaagagtta gttgataagt tgatgagttc
      721 tactgataaa gaagaagttt taaagacact aaagtcttta taaaaataaa aaagtactaa
      781 aaataaaaaa tataaaaata aaaattatta ggaggaaata aaaatgaaaa aaatattagt
      841 agcatgtgga gcaggaatag caacatcaac agtagtttgt gacaaggtag agagattagt
      901 taaggaaaat aatatacaag cagaagttat acaatgcaaa atagctgaat gtgcaacaaa
      961 gcaagaagga gcagatttaa tagtatcaac aactatacta ccaacaactt ataatatacc
     1021 agcaataaaa gcaacagcat atataactgg agtaaataca gcagcattag ataaaaaaat
     1081 attagatgct ttaaaataat cctatcatag atacattgaa ataatatttt ataaaacaga
     1141 aaaaggagga tttataaatg gataaattat tagcagtagt acaatacatt ttaaatatgg
     1201 gaccgacagt aatactacca ataacaattg tagtactagg aatgatattt agaattaagt
     1261 ttacaaaagc tttaaagtca ggtcttacaa ttggtatagg atttgtgggt ataaacttag
     1321 ttgtaaacct attaacatca acactagggc cagcggctca aggaatggtt gaaagattcg
     1381 gacttaattt aacagtaata gatgttggtt ggccaacaac agcatcagca acatgggctt
     1441 caccagttgc accaatatta ataccagttt gtttattagt aaacttacta ttattatact
     1501 tcaataaaac aaagatatta aacgttgata tatggaatta ttggcacttt atagtagcag
     1561 gtgcagttgg atatatagta acaggaagtt atgtttgggc tatattctgt gcaatactaa
     1621 tggagttatt agtactgttt attgcagaaa agacagcaaa aaatgttcag gagttttatg
     1681 atttagaagg tatagcatta ccaactggtt caacagcttc atttgctcca cttggatatt
     1741 tagtaggtaa atttgttgaa aaaataccag gaataaataa aatacaagca gacccagact
     1801 ctatacaaaa aagatttggt atatttggag aaccaatgat gatggggatt atactaggta
     1861 taatacttgg agcacttgcg ggatatgatg tagcaggaat attcaatgta ggtatatcaa
     1921 tgggtgcagt aatgttactt atgcctagaa tggttagaat attaatggaa ggtttaattc
     1981 caatttcaga atcaataaga gatttcttac aagcaaaata tggagacaga gaactttata
     2041 taggtctgga tgcagcagta gcaactggac atccagcagt tatatcaaca gctcttatac
     2101 ttgttcctat aactttgttc ttagcagtta tactaccagg aaacaaagtt ttaccatttg
     2161 gagacttagc gacaatacca ttttatatgg catttatagt gtgttttaga aaaggtaata
     2221 tagttcaatc agttataaca ggaacaatag taatagctat atcactttat atggctacaa
     2281 actttgcaga tgttcataca caattattac aacaagcaaa tatgatgcca gaaggaacaa
     2341 caatggttac aagtatagat acaggtggaa acttgctaaa atggggaata ttgaaattat
     2401 ctcaattagt ttcttcattt ggaatattct agtatgtagt taatagagat tactcttttt
     2461 tagtaaagta tgcgaaaatt taacatttag cagctactaa aaaagagtaa tattttttat
     2521 aaatttttaa aaatacaaaa tacaagagga ggagatttat cgtgaaagca gcagtattac
     2581 atggcacaaa tgatatgaga tttgaagata tagaaataaa accatgtgaa agtgatgaag
     2641 taaaaataaa agttatggca gcaggaatat gtgggtcaga tcctccaaga gtattaaaac
     2701 attggaaata tccagttcca gctataccag gacatgagtt ttctggagta attgctgaag
     2761 ttggtaagga tgtaaaaaat gtaaaagttg gagatagagt agttgcaatt ccttttatac
     2821 cttgtaatga atgtgaatat tgtaaaagag gattattttc attgtgtgat aaccatggaa
     2881 tgttaggagc taaaagtttt ggagcttttg cagagtatgt aaatataaaa gctacaaatg
     2941 tacttccaat aggagatatg aactttgaag atgctgcaat gatagagcca ctagcagttg
     3001 ctatgcatgg agtacttaat ataggtgttc aagttggaga cactgtagct gtaatgggta
     3061 gtggaacaat ggggcagttg gtaatacaag gacttaaaat agcaggggca ggaacaatta
     3121 tagcagttga tatatctgat aataaattaa gagaatcaaa ggaattaggg gctgatataa
     3181 taattaatgc taaagatatt aacccagtag aaaaaataaa agaacttact ggtggaaaag
     3241 gtgttgacat agctcttgaa tgtgcaggtt caaaaataac tcaagaacaa tgtttactta
     3301 taactaaaaa gaaaagtaag ataggatttt tagggatagc atattcagat ataactttat
     3361 cagaagaagc atttgaaaat atatttagaa aagaactaga attaaaaggt ttttggaact
     3421 cttattctgc accatttcca ggacaagaat ggactaaggg aatcaatcta gttaatgaag
     3481 gaaagataaa attaaaagaa atggtatctc atagattctc acttgaagat acttacaaag
     3541 catttgaaat gataagagat agaaaagaag aatttaacaa aatattaatt ttaccacaag
     3601 gggttgaaaa ataatgaaag cagtagttaa aactaaacca ggctatgata atgtagaagt
     3661 tttagaagta gaagaaccaa aagctacagg agacaaggtt aaaataaaag tagaatatag
     3721 tggtatatgt ggttcagata tacattcatt taaaggtgaa tatgcaaata taaaagcccc
     3781 agtaacatta ggtcatgaat tttctggaat tgttgtagaa gtaggagaag atgttaaaaa
     3841 tataaaagta ggagatagag ttacatcaga gactactttt gcaacttgtg agaaatgtat
     3901 atattgtgaa actaaagatt ataacttatg cccaactaga aaaggtattg gtactcaagt
     3961 aaatggaagt tttgctgagt atgtattatc aagagaagaa agcatacatg tacttcctga
     4021 aaatgtatct ttattatcag cagcccttac agagccacta gcttgttgtg ttcatgcagc
     4081 tcttgaaaag actactatag aaagttctga tacagtttta ataataggac caggaccaat
     4141 tggtttatta ttagctcaag ttgttaaatc tcaaggtgct acagttataa tgtctggtgt
     4201 tacaaaagat aaggaaagat tagaaatagc taaaaatctt ggagtagata gaactgtaaa
     4261 tgtaatgaaa gaaagtttgg cagatgtagt gaatgaaatg actgatggaa atggagtaaa
     4321 caaaggattt gattgttctg ggtttatgcc agcagttaac gaagccttaa gactgcttag
     4381 aaaaaaaggt actttcgtac aagttggaat ctttgctaaa aaattaaatg aaatggacca
     4441 agaagcaata atccaaagag agttacaata tataggaagc aggtctcaaa agccaagttc
     4501 ttggattaca gcattagatt taatggcaaa tgggaaagta aatacagaag ctttagttac
     4561 tagaactgtt ggtttagacg aatttaaaga aggtattaca gctttaatga acggggaaga
     4621 aataaaagta gcagtaaaat cttaaaaaaa catttgtatt attttaaaaa aaattgtaaa
     4681 atctactgta ggataaaaaa atgtaaggtc ttaaaaaata acaggaggaa gaaagtatga
     4741 gcactcttag agatcattct aataatatta gaaaaaacat aataaaaatg gttgcagaag
     4801 ctaaaagcgg acatccaggt ggttcattat caatagctga tatgttgaca gtattatatt
     4861 ttgataagat gaacgtatgt gcagaaaatc caaaaatggc tgatagagat agatttgttc
     4921 tatcaaaagg tcatgcagca ccagctttat atgctacatt agcagaaaaa ggatttttcc
     4981 cagaagaaga attaataaca ctaagaaaat ttggttctaa gttacaaggt catccagaca
     5041 tgaaaaaagt agcaggaatc gatatgtcta ctggttctct tggtcaaggg ctatctgcag
     5101 caaatggtat ggcacttgca ggaaaattag ataacaaaga ctatacagta tatactatat
     5161 taggtgatgg agaaatccaa gaaggtcaaa tatgggaagc tgcaatgaca gcatcacatt
     5221 acaaattaga taatttaatt gcatttgttg acttaaatgg attacaaata gatggttcta
     5281 atgaagaagt aatgaatgta aatccagtag atgacaaatt caaatctttt ggatggaatg
     5341 taatagtaat aaatggacat tcttttgaag aaataggaaa tgcagttgat gaagctaaaa
     5401 aagttacagg aaaaccaact gtaataatag ctaaaacagt aaaaggtaaa ggtgtttcat
     5461 ttatggaaaa taatgctgca tggcatggaa cagctccaaa tgcagaacaa gcagagcaag
     5521 cattgaaaga tttagaagga ggtctatagg aatgggaata gcaactagag aagcttacgg
     5581 acaagtgtta aaagaacttg cagaaaataa agatatagta gtattagatg cagatttagg
     5641 aaaagctaca aaaagtatat catttaaaga agttgcccca gatagatttt ttgacatggg
     5701 gatagcagaa ggtgacatga ttggtacagc agcaggtctt gctacttgtg gaaaaatacc
     5761 ttttgcgagt acttttgcaa tatttgcagc aggaagaggc tatgagcaaa taagaaactc
     5821 tgtagcatat ccaaatttaa atgtaaaaat agcagctact catgcaggtg taacagtagg
     5881 tgaagatggt ggtagccatc aagctataga ggatatatct ctaatgagag gtataccaaa
     5941 tatggttgta ttaaatccag cagatgcttt agaagcaaga caagctattc ttgcatctat
     6001 tgattataat ggacctgttt atataagatt aggtagagct gcaactcctg atgtaaacag
     6061 tgaaaattat aaatttgaaa taggaaaagg aactgtttta agagaaggtt ctgacataac
     6121 agtaatagct acaggaataa tggtagcaaa agccttagaa gcagcagaag aacttgctaa
     6181 agaaggtata aatgtagaag ttgttaatat atctacaata aaaccattag atgaagcatt
     6241 aataaaagaa actgctaaga aaactggaaa agtagttaca gcagaggagc acagtataat
     6301 aggtggttta ggttcagctg tatgtgaagc tttagcagaa actaaagatg tagtagttag
     6361 aagaattggt gttaaagatg tatttggtca atcaggtaca ccagctgatt tattaaaaca
     6421 ctatggttta actacagaag atatagtaaa aaatataaaa gagttattat agatataaat
     6481 atatctaaat aacaaattga tttgacataa gtcaattaaa gctgtcttaa aaatagaaag
     6541 aaatttctac aatgggacag ctttattttt acaatacttt atttttatga taattataaa
     6601 atagtctgaa agtaatcaaa aaaattataa aaagaggtgc tatttaatga aaatatctat
     6661 tggatgtgac catggtggtt atgaattaaa ggaatatata aaggaaaatt taataaataa
     6721 aggtatagaa gttgaagatg tgggtacaaa ttcaaaagaa agtgtagatt ttccaatata
     6781 tgcaaaaaag gtaagtcaaa atgttcaaag taaaaaatct gatttaggca tactttgttg
     6841 tggaacagga ataggtatgt ctattgcagc aaataagttt aaaggaatca gagcagctgt
     6901 tgtttctgac tgtttttcag ctaaggcaac tagagaacac aataatacaa atgtactttg
     6961 tttaggagaa agagttattg ggaaaggatt agcaatgaga attgttgaag aatggttaaa
     7021 ttcaagttat aatggagaaa gacatgcaag aagattacaa atgattgatg atatagaaaa
     7081 agaaaattta taaatatata atttataaca agggggagcg ttatgtctat tatttgtgct
     7141 tcaataatgt gtgcagacca aatgaagtta aaagaggaat tagaagctct tgaagaagca
     7201 ggtgtaaaat tacttcattg tgatgttatg gatggaatat ttgttaaaaa cttggctatg
     7261 ggaccagagt tattaaaatc aataagtgaa aatacaacaa tacctttaga catacactta
     7321 gccacagaaa ctccagataa atatattgat atgatgtctt atataaagcc aaaatatatt
     7381 tcttttcatg tagaatcaag tacaaatgta aaagctgata tacaaaagtt aagaaattat
     7441 ggtatagggc cagtgttagc aataagccct caaacaagtg tggataaaat agaagaatat
     7501 ataagtttag ttgagggtat cttagtaatg acagtaaatc cagggtttgc aggtcaaaag
     7561 tttaatcttt ctgtattgga taagttggat aaacttacag agatactaaa agattatgat
     7621 aatcctccat ttatagaggt tgatggaaat ataaataagg atactattaa acttatgaat
     7681 ggtaaaaaag tagatatata tgttgttggt acttcagctt tatttaatga taagcctcca
     7741 atttcatata aagataaaat agaagaacta aaagaaagta taaagtaacc atgtaataaa
     7801 attataatat gtttctgttt aatagtaaaa atttaggtgg aaacaagaaa ttttataata
     7861 tttaataaaa attttggttg agtaaggaga attttttatg ggagacctat ataaactaca
     7921 aaatggtact gatattagag gaatagcgta tgaaaatgat tctaaagaag ttaacctaac
     7981 tgtagaagaa gtaaaaaaaa tagctaaagc gtttcatatt tggttaaaag aaaagactaa
     8041 gaaagataaa gtaactgttg ccataggaac tgattctagg ataacaggaa gccaatttag
     8101 aagtactgtt attgaaactt taactaatga tgattgtaat gtaattgatt gtgagattgc
     8161 cacaactcca gctatgttta tgacaactat tatggatgga tacaattctg atggggcgat
     8221 tatgattaca gcaagtcact taccttatta ctataatggt ttaaagtttt tcacagaaag
     8281 tggaggttta gaaaaaactg atataaaaga gatgttggat atagctgtta aaaatgatag
     8341 tgtagactat gaggaagtaa ataaaaaagg tgaagttata gtaaaaaatt taatagaaga
     8401 ttattctaat ttattgatag ataaaattag aaaaggtgta aattcaagta aaaattatga
     8461 aaagcctttt tctgggctta agatattggt tgatgcagga aatggggctg gtggattctt
     8521 tgctgaaaaa gttttacaca tactgggagc agatacgaca ggtagtcagt ttttgaaccc
     8581 agatggtatg ttcccaaatc atatacctaa tcccgaaaac aaagaagcaa tggaaagcat
     8641 atgtaaagct gtgttggata ataagagcga cctaggaata atctttgata cagatgtaga
     8701 cagagctgct attgtaggta aaaatggcaa accaataaat aaaaatgctc ttatagctgt
     8761 tatatcatca atagtattag aagaacatcc aaaaacagct atagtaacag attcgattac
     8821 ttctgaagga cttgctaaat ttataaatga attacaagga agacatcata gatttaaaag
     8881 aggatataaa aatgtaataa atgaagctat aagattaaat agtgaaggtg aagagtgcca
     8941 tttagctata gaaacgtctg gacatgctgc tttaaaagaa aattatttct tagatgatgg
     9001 ggcatattta atagctaaaa ttttaataaa agtagcaaag ctatccttgg aaggaaagac
     9061 tatagaagaa ttgatagaaa accttgaaga agctcaagaa gagaaagaag ttagaatagg
     9121 cattaataaa gaagatttta gaacatatgc agaggatata ttaaaagatt tagattctca
     9181 tgttaagagt attgatggat ggtctgtagc accaaataat tttgaaggca taagagttaa
     9241 ttgtgatgaa tcaaatggag atggatggtt tttacttaga atatcactac atgaaccatt
     9301 attagcttta aatattgaat caaataaaat tggcggagca gaacaaattt attctaagtt
     9361 aaaacttttc ttagaaaaat atgatttaaa aggtctttag ggtaaataga aagaatatat
     9421 ttatattgaa gaataaatgt aaatttgtac ctaagattac aaatattaca aaattgtaat
     9481 cttaggtaac agagatgtaa ctgattatgg aaacactatg tgatattata gatacagaga
     9541 gatgaaatat gtgatgaatt atagagaaat ataatttaaa atgtattaat atcacaccaa
     9601 aaaggtataa tcaaaaaata tgtaaatata aaccccaaca tttagaaaaa gacctctaag
     9661 gaggtttttt tcttgtttaa ataacttaaa atatattttt atattaatat atcaattaac
     9721 tcttctaaaa gtaagcatta ccttaaataa atcagcatct ataattattt ccatgtgtgc
     9781 attttctaat tcaattatat tttgagcaat tgataaacca agaccagagc catctgtttt
     9841 tctagatata tcaccccttc taaatctttc tattaactct tctggtttta gatttagttt
     9901 atcatttgaa atatttttaa acgttaatat tatattttct tcctttataa acatatctat
     9961 atagacccta gtgttaggca tagagtattt tagtatattg caaattagat tctcaaaaac
    10021 tctccaagtt tttttaccat ctatcatggt aaaaacagca tattcaggtg tttctattat
    10081 aaaatctaaa ctgctatttt gaattttgtc ttcaaattct acaatacttt gaattaaaag
    10141 ttctcttata tcggtttttg ttatattaaa ttctacatct ccactactta gcttagatgc
    10201 ttcaaatatg tcatctatta ataattttaa tctttgtgat tttttatcta aaatatttat
    10261 atagtcattt atagtctctc tgtcaaagtc attatttttt aacatatcaa catagcttaa
    10321 tatagatgta agtggagttt ttaagtcatg agatacgttt gtgataagct ctgccttcat
    10381 catttcattt tttatattag catctacagc agtttcaaga ccgcctgtta tattatttat
    10441 acttttggct aaagtagata tttcatcatc tcctataact tctaatttat actttaaatt
    10501 gccattttct atatttttta tattttttga tatgttattt atgtaattaa acttaacaga
    10561 taaaaagttg tatatataaa aatgaaaaac tgtgtttaca agtgtaaata aaattactat
    10621 agctattgcc tcagcataat atatatacat aaagaatatc aaaacaagat attggataat
    10681 agcttgtaca actatagata ttaaaaatac tatagctaat tttttattta tagttttttt
    10741 attatacata ctaagtaagt ttgaaaagaa tacatatgtt atagacatat cttttagatt
    10801 atagttatta tatttaatat tttcatatat tatatagact atagatataa ttataaaatt
    10861 gtagattatt aaattagtgt tgtaaaacat tttattactt gtaaatgcat gaaaccttaa
    10921 ggttaatagt atcaaagtta atataagtgt aagttctatt tttaccttag aaaaaaggtt
    10981 tatgacattc tctaagaatt tgactttagt ttgtttattt tttttataca atgtaaaaca
    11041 tagtatagtc aataaaaaac ttgataatat aatacctatg cagacaaact ctaattctac
    11101 ttttgacaaa tgtacaggag taccgaaaaa ataaaaatga gggagagcaa actctctata
    11161 ataataatta atattagaaa agttattatt caaatcataa actgcttcaa ataatataga
    11221 aactaataga aacagtaata ataataaaat aaattttgct ttagaatcat taataattaa
    11281 gtttttcaat tttgtaacca atgccccaca ccacctttaa atattttggt tcttttggat
    11341 taatttcaat cttttctcta attcttctaa tatgaacagc aatagttctc tcacaactat
    11401 aagcatcctc attccagaca ttttcataaa tctcatgaga agagaaaatt ttaccttttc
    11461 gtgacataag aagtgtaagt attttatatt caagtggtgt cattttaatt tcctcaccat
    11521 ctaaagaaac tatttttgta tctgtattta gctctaggcc accacttttt agaatataat
    11581 tagtatcatt tgagttattt gtattactaa aatcacctaa atttatatac cttctaagtt
    11641 gagattttac tcgagcagta agttctagtg gattaaatgg tttagttata tagtcatcag
    11701 cacccatatt aagacctata attttgtcca tatcttctga ttttgcagat aagagaatta
    11761 ttggtatatt ccttttttct cttattttaa gtgtagtttt aagcccatct aaattgggca
    11821 tcattacatc cattattatt aatttaatat cattttcgat tagtatgtcc aatgcttcaa
    11881 gtccatcata tgcctttaaa acattaaagt tatcaggtct caaatagaac tctatagcat
    11941 caactatctc tctatcatca tctacaacca atatattttg attcaattta ttaaccccct
    12001 tgaaatttta tttttaacca atttttattt tataccaaaa agaggtatta gaaaacagta
    12061 agcccgttca ttatgaaata aaaactagta cttttaatat attgtcaatg catatagtaa
    12121 atttaaaagt atagacgccc atattaatct gaaggtaaaa gtttatgaaa atatctaggg
    12181 taatctatca cacttcttat gttattttgg tttattaatt ttttaggttt aaacatatat
    12241 taacaaatat aaataacaaa tgagtttcat aattattaag aatttataac aaatatttat
    12301 tttaatgtag tttaatataa acaggtagtt taatgtaggt atgtataaag catttaataa
    12361 ggcttatagg ttttaatgat gatatcttta tatattttaa gagatgatga aattagatat
    12421 gggtaatagt tgtatgagaa aaagtagtat agcacaaaaa gtgctatatc acaaaatctc
    12481 aaataatttc ctttttataa cttaaattaa agaataaata tttcttataa attaggtgta
    12541 tgaagtatag caggaacatc tttattattt aataacttat caaatgattt atggtcagac
    12601 ttatagccaa taccttctct atattctaat tcatcaacaa ttttgtattg ttgacaggca
    12661 tttttaacct tttcatagtc ctcagtagaa tgagctttat aaactatctt attattaaaa
    12721 gttattttat cagcaaattt aggttttaca aaatatttag catcttttat tttaccagca
    12781 ttatataaat tttggataac agaaccattt tttaaatgtt gtaaatggtc atctaattta
    12841 taagtatgtg ctatatgagt tacattttta aatttttctt caaatgtaag agcaattttt
    12901 tccatgtaat tgaagtcagt attaccattt gtatttgttt ctggtaataa tattatattt
    12961 tcccttatta caccaaggct attaagagaa gctaaaaatt ctctatttct atattctgat
    13021 ttttgtatat ttgttaggtt ttcatatttt ttatatttat caaagacgga tataccacat
    13081 ccagtagata ctaaaaccac aaatacatga ttttttcctc tttcttttat agcattaaca
    13141 atagcactcc cagcccacaa cacttcatca tcttgatgct gaacatagaa gacaacataa
    13201 tctttaaatt ttttatgact ataattcaca tagctactaa aagcggttaa aatcaaacat
    13261 aaaactagaa taatagatag aattttatat ttatttatag taaatttttt attcttaaat
    13321 gtcatttaat catctcctga aaggttggct tagttatatt atcaaacaaa gtactaaaaa
    13381 ttatttctta aatgctgaaa aatatagagt agattaatgg aataaaattt ttttattagt
    13441 ttaaaataaa gaaaacattt atgtataaga ctaatcaaaa tattaatgat tgataggaat
    13501 tgagatttaa agggattgta catttattcg ggattcattt taatagaatt ttactttagt
    13561 acttagaata aaagtaataa ctttttaaat ttaaagagta cacatatata tttgtgtact
    13621 ccttgatgat atgattgctt atttactaca aaaacagagt ctttttaaac ctaaaatatt
    13681 tgatgcacca gctatcgtag ttccataata gtaaactggt ttgttaagtg atagaaaatt
    13741 tataattgag ttattacata atgtacttcc tgtgcaaatc actaaatcag cccaagatat
    13801 tacatcttca taatctcgta taccatcttc aatcttaaca ttatattgaa tagtatccac
    13861 aaattcagga tttaaatcta atactcttgt ttcgaaaaag tccttaatat tatcaattat
    13921 ggctggttga tatcctataa ttgctacttt tggattacca aattccattt ttataaactc
    13981 agggaatttt tttgcacata cctctggctc gttattttta caatgaatgg ttctatccgt
    14041 cttgcctaag tatttcataa ctgcatttaa tgatgctata aaaagacttc tatcatgaga
    14101 attgtcatgt aaatctaatg ataatatgtc ttttaaagaa ccttcaaatg tagatggagt
    14161 agaagtaaat gcttgtcctt tagctccttt aaagtcagct tcaagcatta tttctttacc
    14221 aactataatt gggaaatctt tacgcttagt atttccaatt gcttcttttg aagatagaga
    14281 tttggacaca atacttatca tatccatatt taaattatat ttatcgactt gtactaatag
    14341 ataatctctc aaaatatcaa atatattcat agaaaaaaga ttctccttta ttttttattt
    14401 cttcatttaa atcaaaaata tgatttattt ttccattgtt cattattcct atcttatgag
    14461 caaaaaacat tgcttcagaa atatcatgag taacatgaat cactgttggt ttgtatttta
    14521 tgtagacatc cttcaaaatt ttgcttatat gtttttttgt aatataatcc aatgaactca
    14581 taggttcatc taaaagtaat atatcaggtt cagctattaa ggcacgtgca aaagcaactc
    14641 gttgcttttc gcctccactt aaatttttag gatacctatt ttttatatct tctatctgca
    14701 ttaatttaga caagtggtta gccttaagaa tctgttcatc tataggtatt tttctcaatt
    14761 taagtggaaa ccttatatta tcttcaacat tcatatttgg aaataattca aaattttgat
    14821 atacaaatcc tatatttcta ttttctggag gtaagtttga tattaaattt tctttgtatg
    14881 atacatttcc tttagcagat ggatatcttc ctgctaatgt ttctagaaat agagttttac
    14941 ctgacccact agctcctaat aaaacaaagt attcatgatt attaatattt aaactatttt
    15001 cttgtaattt aaaattaggt aaatcaagag ataaattttt tatttttaac atattaattc
    15061 ttatcaacct ctctattaaa aaatatctca aaaagcatca agcatgtaag tgagagaaat
    15121 atcaaaatta cagctattcc gatagcaatg tctatatcac cagtagacat atttaaatat
    15181 atagatgtag gaataatttc agttttcata cgtgtagaac ctgctatcat agctactgca
    15241 ccaaattcac caagtgctct tgaccaagtc attacagttg cagatatgat tccagttttt
    15301 agatttggaa gaattataaa tctaaatgct tcccaactat tacatccaag ggtacgtgca
    15361 acaaatatca tcttttcatt actttcattt aatgaagtgt gaagtatttt aatagtaagt
    15421 ggaagattta caaatatttg tgctaaaact ataccttgct ttgtaaatat aaaatcaagc
    15481 ttaaaaatct tataaatgga atctccaatc cccattcttc caaacaaaag taaaagagca
    15541 attcctgata ctaagtgtgg aagagacata gggagattta ttatctgtat aatcagtttt
    15601 ttaaatggta atttagtaat atgtaaaaaa tatgctactg gaatagctaa taaaaggcat
    15661 actatagtag atattaaaga tgttttaata ctaagtgtta ttgcatactg tacttccact
    15721 gattttaagc atataggaac ataacttatc cctttaatga ttaacataag aagtggtgat
    15781 acaataaaca aaaagactat agcaaaaaat ccagtaagta gagtagtaaa aaatttattt
    15841 ttcaagttta atcactactt aacaggttca aaaccatatt ttttaaatat ctgtttagct
    15901 tcgtctgact ctatataatt tataaattta ttagctaaat cttttttatc actatagttt
    15961 acgattcctg ctgatatgag ttggtctata tttttatctt gggcaatttc tataacttct
    16021 acatcttcat taccaaagac cgaatctttt gtggctattg tagcatcagc tttacttgat
    16081 gttaactgta caatcatttc atttacagtt gcagctgtag agacaacatt atcatttata
    16141 gattttaaat tatttttttc aagtattttt tgtgtagtct tacctatagc attagactct
    16201 ttgtctccca aaataagttt aactccatct ttatttaagt cttccaattt ttgaatatta
    16261 gctggatttc ctttaggtac aactattgca ggtgtatgat gtgcaaccgt tttatgttca
    16321 cctacaagtt ctttttcaaa ggcctttgaa taaattggtt cagaaccaac aataaatacg
    16381 tctcctttgt gacttgtctc aatttgagct attagctgtg cagaacctgc atagctatat
    16441 tcaactttga cattattttc tttctcaaat ttttttgcta tttcatccat tggtttcttt
    16501 aaacctgccc ctgaatagac aaaaagagtc tctttttctt ttgaatcatc agctgttgtc
    16561 actttagtat tagattcatc attagctttg ttttctttag aattacatgc agtaatactt
    16621 aatgaaataa tcatagctaa agctagtact gaaagttttt taaacataag atattccccc
    16681 ttattaaatt agtgtaaatt cttttttagt atatcatact aagaaaacga tgtctaagtt
    16741 tttgttgtgt tttataatgt tttgttatgt tttgttatgt atagttaaga aaaaatctat
    16801 tcataatgtc atttccatag gtagttattt tatttttaat ttttattaat actttaaagt
    16861 attttaaatt taaaaactta aatcaaatta acttattgta gattttttac tttttaacta
    16921 attttatatt tattatattt cagtgaaaaa atagaacatt gaaacatata gatatgtttt
    16981 aattgctttt tattaacaaa ttactaaaag tattatatca gaattgaata caaaagaaag
    17041 agtatgtatt tatgagatag ttgaaaattt tgatgtgcca caactaaaat tattatatta
    17101 ctatatattc taattaaaag agtacttgta ggtttaagta catactttat aaatatattt
    17161 ttgtcagatt tattttataa aaagtattta gactaagtat tatttttaag tatttttttg
    17221 ttgaagttat tttttccttt tttacaaaat gcgtaaataa aaaaaagact cttaaaagag
    17281 tctttccgaa aaatctatat attataatat agttatattt tctgcttgag gacctctagc
    17341 gcctttaact atatcaaagc ttactttttg accttcttct aatgatttaa atcctgaagt
    17401 ttgtatagct gagaaatgag caaatacgtc atctccactt tccattgata taaatccaaa
    17461 tcctttttca ttattaaacc attttactat tccattattc attaaaaata ctcctattaa
    17521 cctatatcaa gatatacttg atttacttgt gtattaccac aaatactatt gtatcataga
    17581 ttaacataaa tgtctattta attataattt ttagttaaca tttttattta ttcttaatat
    17641 gaaaataaat ttaaacattt tatattacca atatattaat gtaaatgtag ataaaactaa
    17701 aaagggtttt ctagaaaaaa atctgtctaa ttatacttac ttaccaatac catcacttga
    17761 tgcaagcaag attccacaac tttttctccg tactctaata taaaatcatc taactgtgta
    17821 tctataaaat cacaataatc atatgaacta ccaatataag cagttaacat atgtgtacat
    17881 ttatccattt tatctctaaa cataatgtat ttatccccct aaaaaacttt catgaaaaac
    17941 aaaaagaaaa tatctttttg gcaactggct gacataactt attttataag cgttagtccc
    18001 tatagctttg cgtcactaaa tttctctagt tttgccgatt tagttttatt ctacagatta
    18061 ataatacaat agaattagtt attattcaac atatctagct gaaaaattaa taaatttata
    18121 tatgaacgtt aaattatctg aaaaaataaa aagcccctct gtcaggagtg acttaaaaat
    18181 tgaatttaag tttgtattta aaacacattt ttaataatgc aaaaactaat caaaaataaa
    18241 caattcatca ataggtgtat ctactatttt tgatatatct attgctaatt tcaaagaagg
    18301 attatacttt cctgcttcta aacgcataat ggtttctctt ctaactccta ctttttctgc
    18361 taattgttct tgagttaatt cttttaattg tctatatttt tttaggttac aagtgaattt
    18421 aggcatatta tttttcctct aaaatataaa gttttatagc ataaacattt aaagtgattg
    18481 catatgtaat tgatagtaaa acacacatta attctatatt cctagacact atagtaatac
    18541 accataaaat gaataattct ataatagcaa gctgtcctgt aaatgccata gctgcttttt
    18601 catcttgtac atacctttca tctgctttat caccatttat ttttgctata ataaagtttg
    18661 agaaaaaagc aaaaaatcca atatatgtaa ggtcagcaac attgccagat gaaaaatatc
    18721 taagacttaa aaatccaagg aaaccacaaa aacccataaa aaattttttc tgaatcattt
    18781 tttatcctcc ttagtaattt taaaagagat atatttatat ctttatgata caaatatatc
    18841 tcttttatat tcttttgtca atagaaaatc agtattatac aatatttgta ctgcaccata
    18901 attgttagag caaaaatcta ctgcttgaga tgtttatgta tgactaaata tgattttaat
    18961 ttcaaattaa aagtagctaa attttatttg aatagagaag gaagagatat tttaatagta
    19021 aaacaatatg gagtttataa ccattctcaa gttgaaagat gggttaatat attaggagag
    19081 tgtgcactaa aaataaaaaa aattttctat actatatggt tcaagttaga tgttataaac
    19141 tatatgatga taactaaata tagtgtacaa taaatcgcta agtattttgg aataaacaat
    19201 agcacagtta tagcaacatg aaaataaaaa tttttacata gtggtgttga tgccttttct
    19261 aaaatgaaag gaagaccata atgaataaaa acaaaaacac taaagaaaaa ataaattaac
    19321 aagagaacaa gaattagaat atgaaaataa atttttaaaa gatgagcttg agtttttaaa
    19381 aaagatgtgt gtctcaggga agccacatta aaaaacagtg gtatcattat taatcaaaag
    19441 aaagttagat gtattatcaa aaaattagaa cttaaatgca tagcattttt tcataaatca
    19501 cataaatata actcctataa aggtataatt ggaaaagtaa aaaataataa aacaaataga
    19561 agatttaaaa catcaatagc atatcagaaa ataacaaatg atatgctaga atttataaaa
    19621 tatatctaat gataaaaatg gaaaatcaat tataaaaaag gcatatctcg attcattttt
    19681 tgttatatag tcaaataaga atactataga tgaaagatac gattttgcat atgtattaag
    19741 taagtattct gatgtttttg gttgatacac atgcaataaa gaagttgtgt ttgcagataa
    19801 attagcaaaa ctatagtata agttgcaaca ataaagaaaa tgaaaattat catactaaag
    19861 cataaggcat gttacaattt tattagatag gacattaaca tacactaaag tactttttat
    19921 tataaagagt acttattttt ttgaaattca ttaatgtata aactatcaag aatattactc
    19981 aacataattt aaaaacaact tgaataggta tttttaaatt atgtgatata ataaaaaata
    20041 gaagtgtatg ccaatacact tctgtagtta taactaagca ttctattctt gaggagtgct
    20101 tttttcattt ttataaccaa ctctttttac tttaacaata attatcagac ctatatattt
    20161 atttttaatt gtctgattta ttagataaaa aagttattat catattttta tcatttggta
    20221 ttgttattga actaccataa tcttcttcta atttatctag accactttta cttatttctc
    20281 catctataat tatgtttaat tctaagtatt cttcactacc attagatgac actaaagtgt
    20341 acgaaccatt ataaggcatg cctaaatttt ctattttatg tgccaaaggg tcttcatcac
    20401 caataccaga gtttactgtt atttttccat cttttttagt ccaccatatt atgtttcctt
    20461 cagtatattt tgattcatct gcatagtagc taagagacgc actttttatt gcacttatat
    20521 cagcttcaag tttagctatc tttgcttttt ctatattttt aaataatgct ggaagtgcta
    20581 ctattgccaa tattcctatt atagcaatta ctactaataa ttccactaga gtaaatcctt
    20641 ttttattttt catttatttc ccctccatat aaaattaata atatataaat ttttattttg
    20701 ttgatttcta ctttctatat tttaccatat atagacaaaa aaatcacttt ctatgacaaa
    20761 tatactatta ttttacaatt tatggaaatg atttaaaatg acatttcttg ttagaaaaga
    20821 tataagaaat ggattaaaat aaagaaaact acagtcatat caatgtcaat aatattattt
    20881 aaaagcagat gaaaataaaa agaggactca gaaaataatg tctatttaat tatacttact
    20941 taccaatacc ataacttgat ataaacaaga ttatactaca tttttttatg ctctagtata
    21001 aaatcatcta actgtgtatc tataaaatca aaataattat atgaactatc agtataataa
    21061 gtcaaaatat gtatacatga atacatattt taaaagatat atattattac atacctaaaa
    21121 aactttcata aaaacaaaaa taaaatatgc ttttagtaac ttgttaacat aacttataat
    21181 ttattttata agcattagcc tatatagctt tgtgctacta aatctctttg attctaacga
    21241 tttagtgcta ttctacaact aaaataatac aatagagcta tttattgttt ggtagcattg
    21301 tttgtaaatt aaacaaattt atacatatga atattatttt acattcaaaa aaacagacta
    21361 aatatgtaga atatttggta aaacttacct ctagtttttg tcttaaaaag ctcctattat
    21421 taacttaagt tagaagaatt aaggaagtga cataaattga aagaagaaat attaatagaa
    21481 aaattattaa gagcagaatt aatagtaatg gagtatttat ggaaaaaaga cactctaatg
    21541 cctaaaaaag aaattgtaaa agaaataaaa cagatttatg gatggcataa aagtacaata
    21601 aaaatactac taaaaaggct agttgctaaa aggtatttgg ctagatatat tataaattct
    21661 caatctcatt ataaaataat agatagtaaa gaatattata cttttaagaa aaaggtacta
    21721 aaatctagta aaagcataaa aataatgcgt tcacttacca ctacacataa aaatgtaagt
    21781 aaagagaagt tagacctatt agatgagtat tatagaaact taaaagaatg atatagtaaa
    21841 aatcgaatgt aattatttac cttaattctt ttgtttgtaa aactttattg atacagaatt
    21901 taacatatac ataaattggt aaaggaatgt atactatgaa aattagtaaa ttaccagaag
    21961 cggaattaaa agttatgaga tatatttggg aatcagaaaa ggtattaata tcaagagaaa
    22021 tcaccaagtc tatggaacaa aaatatgaat ggaaagatac aactatattt acagtattaa
    22081 aaagattact aaagaagaga gtttttagaa gcggagaaaa tagataagtg tacacactat
    22141 aatgtattag taaaaaaaat aatatcagag attttaaaca aaagaatttt taaagaatac
    22201 acataaaaat tcaatattaa gtttaatgtc agcactatgt agtaaggatg atgaagtaga
    22261 tggtgatatt ttaaatttat tagaagaat
//
LOCUS       DAEOTL010000067        22155 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEOTL010000067 DAEOTL010000000
VERSION     DAEOTL010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.067"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            110..1294
                     /locus_tag="KRH82_002829"
     CDS             110..1294
                     /locus_tag="KRH82_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656097.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(1671..2780)
                     /locus_tag="KRH82_002830"
     CDS             complement(1671..2780)
                     /locus_tag="KRH82_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBG8656098.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            3243..4436
                     /gene="nifV"
                     /locus_tag="KRH82_002831"
     CDS             3243..4436
                     /gene="nifV"
                     /locus_tag="KRH82_002831"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBG8656099.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            4461..6386
                     /locus_tag="KRH82_002832"
     CDS             4461..6386
                     /locus_tag="KRH82_002832"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBG8656100.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREEAWIELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            6408..7403
                     /locus_tag="KRH82_002833"
     CDS             6408..7403
                     /locus_tag="KRH82_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBG8656101.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            7729..8202
                     /locus_tag="KRH82_002834"
     CDS             7729..8202
                     /locus_tag="KRH82_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656102.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            8236..8730
                     /locus_tag="KRH82_002835"
     CDS             8236..8730
                     /locus_tag="KRH82_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656103.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            8827..9348
                     /locus_tag="KRH82_002836"
     CDS             8827..9348
                     /locus_tag="KRH82_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBG8656104.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            9537..9848
                     /locus_tag="KRH82_002837"
     CDS             9537..9848
                     /locus_tag="KRH82_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBG8656105.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            9876..10562
                     /locus_tag="KRH82_002838"
     CDS             9876..10562
                     /locus_tag="KRH82_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8656106.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            10794..11678
                     /locus_tag="KRH82_002839"
     CDS             10794..11678
                     /locus_tag="KRH82_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBG8656107.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPYIVHKEEFEHPLKLDISSV
                     VNGEVRQNSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            11777..12952
                     /locus_tag="KRH82_002840"
     CDS             11777..12952
                     /locus_tag="KRH82_002840"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBG8656108.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            13080..13934
                     /locus_tag="KRH82_002841"
     CDS             13080..13934
                     /locus_tag="KRH82_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656109.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFYEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            13978..15213
                     /locus_tag="KRH82_002842"
     CDS             13978..15213
                     /locus_tag="KRH82_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBG8656110.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            15314..16255
                     /locus_tag="KRH82_002843"
     CDS             15314..16255
                     /locus_tag="KRH82_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBG8656111.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(16474..16827)
                     /locus_tag="KRH82_002844"
     CDS             complement(16474..16827)
                     /locus_tag="KRH82_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBG8656112.1"
                     /translation="MDRKRELKQLYKEMKFDIGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFIFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            17123..18034
                     /locus_tag="KRH82_002845"
     CDS             17123..18034
                     /locus_tag="KRH82_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBG8656113.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            18295..18729
                     /locus_tag="KRH82_002846"
     CDS             18295..18729
                     /locus_tag="KRH82_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656114.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            18752..20287
                     /locus_tag="KRH82_002847"
     CDS             18752..20287
                     /locus_tag="KRH82_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656115.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EISLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVVLVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDEVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            20371..21738
                     /locus_tag="KRH82_002848"
     CDS             20371..21738
                     /locus_tag="KRH82_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656116.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            21773..21997
                     /locus_tag="KRH82_002849"
     CDS             21773..21997
                     /locus_tag="KRH82_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBG8656117.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
BASE COUNT         8639 a         2228 c         4059 g         7229 t
ORIGIN      
        1 taaagtcatt ggaaaaatat agttgaattt aatgagcaaa aatgttattg ttttatcaat
       61 aaagtgttaa aataaaaact ttcaatatca ttttagggag gatgatttca tgcaaaaaag
      121 tgtaaagaaa gcaaaagtaa cgggctctat gttagctatt tttggtgttg caagcgttct
      181 ttttagttca catgcaggag gaggatttgc tacagggaat caagaaactc agtactatgt
      241 gcagtatgga tggacagcac cacttatggc aattttagca atgattatac ttactgctac
      301 catgagagaa gttatcataa tgtataataa taacaattgt aggaattata aggatttatt
      361 ttgtgagctt tggagaccat atccaaaact tgaaataata tgggagatat attactatct
      421 aatggtttta atagctgtaa gtgctgttat agcaggtgca gcagcagtat ttcaaagtat
      481 aggagtaaat tattttgtag ctgtatttat tattggagtt gtacttcttg tctttactat
      541 atttggtgct atgcttgtat ctaaagcagc tacagcaatg acaatagcta ttctagtatg
      601 tactcttact atttttattg ttggtataaa agctaaagta ccagaaataa ctgaaatatt
      661 atcaaataga acgagtttca cacctggcta tatcaagcca atacttaata cttttattta
      721 tgcaggtttt caatcggttg ttatacctac acttgcagga tgttcaagac cacttcttaa
      781 gaactcaaaa gaagctacta aggcaatgat aatttcattt gttatgaatg caattgcatt
      841 aggacttgct gtaactatgc taatgggatg gtatagagaa attattgctg ctgggcaaac
      901 aacactccct actctttatg ttgcaggtca atctggaaat catactatat acataattta
      961 taatgttgca ttattccttt gtttaatgtc tacaggagta actactatat ttggtcttgt
     1021 aaatagattt gaagaccata aagcactttc tttcctttct tcaagaatga aaagaagggt
     1081 atttacagct tgtgcaataa tggtagtgtc aatgcttata tcacttacag gattaagtaa
     1141 tattgttaaa tatggatatg gatattgtgg ttatcttggt ctattcacta tagtaattcc
     1201 attccttaca ctaggacatt ataagaataa gaagtttgca aaggaaaatc cagaagctaa
     1261 atggccagcg gaattaaatg aaaatgtaaa ttagatgtag tagcaaaaaa tattgctaaa
     1321 gagaatacta tagataagaa tactatagat aatatatctg catgtttatt aagattattt
     1381 gcaaaatcta atattaaaca actataaaca agcaatataa aactaagaat aaaagataaa
     1441 aagagggtgt ctcaaaatgg acttttagtt tataaggcac tcttttttat atgaagtcaa
     1501 atatattttc attattttga caataaaaga gactaatcct actttggata gcctcttttt
     1561 tctttaatat aaaatagtat aacagcaaag tatagattga tacatgtttt ctgtagcttt
     1621 ctatatatta cagtgtttgt gtggcattgg tattttaagc aatctataaa ttataattct
     1681 ataattcttc tactaatttt agattctata gccgtctcta tttcacttaa cattcgttca
     1741 tttttagggt caataaaagc acatgtatag ccttcttcac cagctctacc agttctacca
     1801 atacggtgga tgtagtcttc tggtgtttct ggtaaatcgt aattatatat atgacttact
     1861 ccagatatat caagaccacg agaagctaca tctgtagcta ttaagtattg tatatctaaa
     1921 tttctaaatg atttcattat tctttctcgt tttgattgag caatatcact atgaagtttt
     1981 tgacaattat atcctcttat agcaagagct tcttcaagat tgtcaaccct tctcttagtt
     2041 ctacaaaata ttattgccat aaaaggatta tcttcatcta gtaccttaca taaggcatct
     2101 aatttttttc tatctgtagt ttctactact tcttgtttta tattgttaag agtgatttct
     2161 tctttttgaa tagaaactac aacaggattt tttgtgtatc tataagctaa tttttttact
     2221 tgagaattta tagttgcaga aaagcatagt gtttgctttt tgtttgaagt ctcttttaaa
     2281 atagcttcca cttcattttt aaatcccata agcaacattt ggtctgcttc atctaaaaca
     2341 aaagtcttca acttactaag gtctattgtt tttctattta gatggtctaa aagcctacct
     2401 ggtgtagcta taatcatatg aatatttcct tttagtttct ttatttgaga accaatatct
     2461 tttcctccat atgctgcaag aatacttaca tctttagatt ctttaagttt catagcttct
     2521 tctgttattt gaatagctag ttctcttgta ggagaaagta taagtacttg tatatcattt
     2581 atatctaatg atatattttc aaatatcgga agtaaaaaag ctagtgtttt tcctgttcca
     2641 gtttgagctt ctgctattac atcttttcct tcttttatta gtttaatact ttctttttgt
     2701 ataggtgtag gtgttgttat tcctgatttt tttagaatat ttattgtatt ttcactaatc
     2761 cctaagcttt tgaaatccat tgttatctta cctttcatga aaaattttct tttttattaa
     2821 ccaattaata atatcatatt tataagtatt tttagtaaat tttttaatta ttatttatat
     2881 agcttaaaaa tatattaaga tactttaaaa tggaatgtaa cttaaattaa attttagtag
     2941 gaattttata ggtttatttt taaaggtttt ttgaaaataa atctatttaa aaattaaatt
     3001 aaaatgcaag aaaaacataa taactttcat ttttaagaag ttttcacaaa aaagaaaaaa
     3061 tatagtgcaa taaatgatac aaagtaatat aatagattac aagatatgaa aagctaaaaa
     3121 aataaattgc aaatgaaatt aaaatgaata aaaaataaaa aaataatcat aagttagagg
     3181 tatcaatgaa aaataagact taatgttttt aaaattaaaa gtatactaag gggggcatta
     3241 atatgtgcgt tatatcaaaa gatagagcaa aggaaataaa aatagtagat actactttaa
     3301 gagatggaga gcaaacagct ggggttgtat ttgcaaatag agaaaaaata atgattgctg
     3361 aaatgttaag tgacctaggt gttgaccaaa ttgaagttgg tatacctact atgggtggag
     3421 atgaaaaaaa tgtaataaag cacatatgta gtagaaattt aaaatcagat ataatggctt
     3481 ggaatagagc agtaataaaa gatgttgaag aatctatttc ttgtggtgtt gatgcagtag
     3541 ctatatcaat atcagtatct gacattcata tagaaaataa attgagaact tctagaggct
     3601 gggttttaga aaatatggct aaaacagttg aatttgcaaa gaaaaatgga ttatatgttt
     3661 cagtaaatgg agaagatgct tcaagagcag atatagactt cttaactgaa tttataaatg
     3721 ttggaaaaca agcaggggca gatagattta gatactgtga tacagtagga gttatgaatc
     3781 ctttttctat aaagaatgca atagaaactc tttatgaaag aactaatttt gatatagaaa
     3841 tgcatacaca taatgacttt gggatggcaa ctgcaaatgc acttgcagga atagcagcag
     3901 gagcaaatta tgttggtgtt acagtaaatg gattaggtga aagagcagga aatgcagcat
     3961 tagaagaagt tttaatggca cttaagtgtg tttataaatg tgatttaaat aatatagata
     4021 ctagaaaatt tagaggaata tgtgagtatg tagcacaggc atcaggaaga atacttccta
     4081 catggaaacc agtagttggg gataatatgt ttatacatga atctggtata catgcagatg
     4141 gagctttaaa agacccacat aactatgaac catttgaccc aagtgaagta aatcttgaaa
     4201 gaaaaatagt aataggtaaa cattcaggaa gagctgcagt tgtaaataag ttgagtgaat
     4261 atgaaatgta tatttctcca gaaaacgcta ccaagctatt aaatgctata agagctacat
     4321 ctataagatt aaaaagaagt ttaatggata aagaaattct tcaattatat tgtgatatac
     4381 tagcacatga gaaaggcaca acagaagaag aagcagttag aggttcatat atttaagata
     4441 taattgttta ggaggaaaat atgggagata atatagttta taaaataatt aaaaaacata
     4501 tagtagatgg agaagctgtt gctggaagtt caattggtat aaaaatagac caaactttaa
     4561 cacaagattc tactggaaca atgacatatc ttcaactaga agctatggga atagataaag
     4621 taaagactaa aagaagtgtg gcatttgtag accataatat gttacaacaa ggatttgaaa
     4681 atgcagacga ccataagtat atacaaacag tggcagataa atatggagtt tatttctcta
     4741 agccaggaaa tggtatttgt catcaagtat ttttagaaag attttcaaca ccaggagata
     4801 cacttttagg ttctgatagc cacacaccta ctgctggagg tgtgggcatg atggctattg
     4861 gagctggtgg attagatgtt gctttagcca tggcaggagg agcatactat ataaaagcac
     4921 caaaagtctg taaggtgaat ctagttggaa aattaaataa tatggtatca tcaaaagata
     4981 taatattaga agtgttaaga aaacaaactg taaaaggtgg agtaggtaaa gtttatgaat
     5041 atggtggaga aggtgtcaaa agcctatctg ttccacaaag agctacaata acaaatatgg
     5101 gggctgaact tggagcaact acttcaatct tcccaagtga tgaaaaaaca ctagaatttt
     5161 ttaagagtca aggaagagaa gaggcatgga tagagctaaa accagatgca gatgcagttt
     5221 atgatgaaga gattactata aacttggatg aattaaaacc attagctgca aaacctcata
     5281 gcccagacaa tgtagatgaa gttgaaaata taggcaagat taaaatagac caagtggcaa
     5341 taggaagttg tacaaattct tcttatgaag acttaatgaa agtagcacaa atcctgaaag
     5401 gaaataaagt acataaggat gtgagtttgg taatagcacc aggttcaaga caagttatgg
     5461 agatgattgc tagaaatggg gctttggcag atataataag tgctggagct agaatactag
     5521 aaaattcttg tggtccatgt attggtatgg gtcaatctcc aggtactgac tctgtgtctt
     5581 taagaacttt caatagaaat ttctatggta gaagtgggac tttgtcagca caagtatatt
     5641 tagtaagtcc agaagtggca gcagtaagtg caatcaaggg agtgcttaca gacccaagag
     5701 aatttgatat taaatttaca aatttagatg taaatgaatt tttgatagat gatagcatga
     5761 taattaaacc tgctgatgta ggaagtgatg tagaagtagt tagagggcct aatataaaac
     5821 ctttccctct taatacagag ctaagtcagt ctataggtgg aaaagttata ttaaagacag
     5881 aagataatat aactactgac catataatgc catcaaatgc taagttactt ccttttagaa
     5941 gtaatatacc gtatcttgca aactattgtt tcaatactgt agatacagaa tttcctcaga
     6001 gagcaaaaga caataatggt ggatttatag ttggtggaga taattatggt caaggttcaa
     6061 gtagagaaca tgcagcttta gcaccattat atctaggtgt taaaggggta atagttaaga
     6121 gctttgcaag aatccacaag gctaacttga taaatagtgg tataattcca atggagtttt
     6181 gtgatgagaa agattatgaa aatatatctc ttttagataa tctggagata ccaaatattt
     6241 tagacaatct aggtagtgga attttagaag ttaagaatac aactaaagga acttctttta
     6301 aggtcaaagt agaattgtca gcaaaagaag ttgatgtatt aaaagctggt ggaaaattaa
     6361 actacactaa aaatcaagct aattaatatg aaaagaggga atattgaatg tataaagtga
     6421 cacttatacc aggagatgga ataggaccag aagttgcgaa agctatgaaa aaggtagtag
     6481 aagctactgg agtagaaata gaatgggaag aagttaatgc aggagaggca gttattgaag
     6541 agtatggtac tccacttcct gaatatatta tagatagtat aaaaaagaac aaaatagcta
     6601 taaaaggccc aattactact cctgtaggta aaggatttag gagtgtaaat gtaactttaa
     6661 gacaggcatt agatttgtat gtcaatttaa gacctattaa aagttttaag gggataaaat
     6721 caagatatga agatgttgat ttagtggttg taagagaaaa tacagaagat ttatatgctg
     6781 gaatagaaca taaaataggt gattatgcag ctgaaagtat aaagataata acaagaagtg
     6841 caagtgaaag aattgttgat tttgcatgta actatgttaa agataataag agaaaaaaag
     6901 ttacagctat acataaggca aatataatga aaatgtctga tggattgttt ttagatgtgt
     6961 ttagagaagt tgcatcaaaa catggtgtag aatatgatga tttgattgta gatgcagcag
     7021 ctatgaactt agttttaaat ccagaaaatt atgatgtaat ggtaatgcca aatctttatg
     7081 gagatatact atcagattta ggtgctgggc ttgttggagg tttaggtata attccaagtg
     7141 caaatattgg taaagattgt gcgatatttg aagctgttca tggaagtgct ccacaaatag
     7201 caggtcaaaa taaggctaat ccaacagcac ttattcaatc atcagtaatg atgcttagat
     7261 acttaggtga atatgaaaat gcacaaaaaa tagaaacagc tttagaaaaa gtatttcttg
     7321 aaggaagtaa attgactgta gatttgggtg gctcagcttc tactacagag tttgcggatg
     7381 aggtgtgtaa gtatattgta tagattttat ttagggaaaa agtaaaatat agattgaagg
     7441 aaagaggctt tctcaaaatg gagataagcc ttttttattg gaatgataaa atatatttga
     7501 ttttatacaa aagagagttc ctcataaacg aaaaagttaa ttttgggata tccattttaa
     7561 ttttaaaatt aattgattaa tatgcaaaga aagattaaat aaatttatta tttttaattg
     7621 aactttcaac caaaatatgg taaaatttaa aaaagttgaa ctttcaacta aaaatgaata
     7681 tattgattat gtgaaattct ataaaacaga aactatttga ctttagccat agtagtttca
     7741 gtggaggtgt gtttgattaa gactttagac agtaatatat taagagaagt aggtacttta
     7801 tctagagcag taaattcaat aaatgatatt aagtacaagg aattaaagtt acaaaaagga
     7861 caatttacat ttttgacaag aatctgtgaa aatcctggta taaatcttgt ggaattatca
     7921 aatatgttaa aggtagacaa ggctacaaca accaaggcta tacaaaaatt aataaaggca
     7981 ggatatgtag ataaaaagca ggatgagttt gataaaagag gatataattt aactccaact
     8041 gataaatctt tggaagttta tgagttgata attgaagaag agaatagaag tatagagata
     8101 tgttttgata attttacaga tgaagaaaaa caagtggtaa ctaagttatt agaaaaaatg
     8161 agcaaaaacg tagaaaatga atggtttaaa gtaaagagat agtaaataaa tacattaact
     8221 taaggagata tttttatgat tagaaaagcg aatatgaatg atttagaaag cattatgaaa
     8281 attataaaat ctacagtgga agaaatgaag acttataata atacacaatg ggatgaaaac
     8341 tatccattag aaaaagactt tgtttcagat attaagaaac aagatttata tatttatgaa
     8401 gtggatggag aagtagcagg gtttatatgt cttaattatg aagagccaga agaatattta
     8461 ggcttaaatt ggtcatctaa taaaaaagca atggtaatac atagaatggc tgtaaatcca
     8521 aactttagaa agacaggaat agcatctaag ttagttgatt ttgctgaaaa attagctgta
     8581 gaaaacaatg tatcatactt aaagagcgat acatattcaa taaactcaaa aatgaattta
     8641 ttacttacaa agtgtggttt tataaaaatc ggagaaatga gttttttagg aaaggagaaa
     8701 tctttctact gttatgataa aatattataa agagcattta taatacaagg ggtaaataat
     8761 agattttcag cattagtaag ggcataatat aacctagtat atgctattat gaaagggatg
     8821 atttatatga ttggatttct aaagaaaaga agaagtatta gaaaatacaa ggatgttgaa
     8881 gtagaaaaag aaaaattaga taaaatatta aaagctgctc ttttagctcc atcatcaaag
     8941 gggcttagaa catgggaatt tatagtggta gatgataaag aaaagctaat taatttatct
     9001 caatgtagaa ctaaaggtgg tggatttttc ttaaaaaatg cacctttagc tattgtaatt
     9061 attgcagata aagaaaaaaa tgatgtttgg atagaggatg caagtatagc tgcttcatac
     9121 atacaacttc aagctcatga actaggttta ggttcttgtt ggatacaagt aagaaataga
     9181 atgcatgatg ataatataga agctgataag tacattagag aagaattaaa agtacctagc
     9241 aagtacagtg tagaatgtat aatttctata ggatatcctg atgaagaaaa gaaagcatac
     9301 agtgactctg atttagacta taaaaaggtt cattttaaca acttttagta tataatatgt
     9361 tgtattaaga cattatattt ttttctattg ttaatatata cttaaaattg taaaaatata
     9421 tctgaatttt actaacttat ctaggggtta tgtacaagga ttttaaagat aaatatagaa
     9481 attaatgttt ataatcgata cataacttga gtaacaaaat ttaaggaggt taaagtatgg
     9541 gtatatttaa aacaaaaatg gatgaggact ggaaagtaaa ctacattaaa gagtttaatg
     9601 aaatgagaga ttcttatgag agtaaacttc aaaaaaaaca gtttgaggta gatagtttga
     9661 aatcagaatt ggatagacta agaagctata aaaatagcct taagccaaaa gaaaaacaaa
     9721 ttactgatga tgatataaat aatataaaga gtttaagaag agatggctta agctataaag
     9781 aaatttcaaa tcaaacaagt tggagcaaag caactgtaag tagggtatta aatggacttt
     9841 acgattagca tatacatggg gtgatttaaa ttgggatgaa gtatagttac aaaaaatgca
     9901 taatagattc tattttattg atgtttatag ttcaaatatt aaggatgatt ttgaattatg
     9961 tacttctaag tcaatttgaa tttactcttg aaaattttaa tattataaac ttaatttctt
    10021 ttacattagt tggtttatcg ttaattttat ttttaaaaga taattctttg tataacaagg
    10081 ttagaaatag aaaaatcaca gaagcttttg aagaaaataa aaacaatata cttattgaaa
    10141 agtgtaagct gatacttttt gttgtggttt tatctttagc aataattgta acttattgta
    10201 ctaagggata tgtacttttt aatgtaacta tgatgacttt gtctgtattg atagttccaa
    10261 tatttgaaga gttatttttt agagaatata tatggaacta tctaagtaat tttataaagt
    10321 caaagagtaa aattatctgt ataacatcta tactatctgg aatttataat ataggataca
    10381 tagatgttat aagaaattat gtaatattgt ataacaattc gagctacacc tttgaagtta
    10441 ttatttcaaa aattatgata ggtactgttt ttggtattgt acttggatta gttaagtata
    10501 ggtttagaga tgtagggttt tgtatattat tgaggagctt atttgctata tttattaggt
    10561 agatagtata atcggtttat aaggttgttt taaatttaat tttaaatcaa ccttatttta
    10621 tttgtgtttt ataaagcact tatatattaa taactaataa atttaataaa aattatttga
    10681 atatttttaa aatatataaa tatgtattga catataaata ttatgaatta caatttatat
    10741 aaactaataa aaattaaata atattaatca acttattgaa tggaggaata aaaatgaaat
    10801 ttgtgacttt ttgtagtagc aatgaagaaa aaataggtgt atttaattca gaaacaaata
    10861 gtatatatga aattaatagt ttaggattaa gtaaattata tactgatatg aatgatttta
    10921 ttgaaaacgt atctacagga gatttagaaa aaataaaaaa caattcattt gaaaacgcaa
    10981 agtgttataa gttagaagaa gttaaattat gttccccaat tgtaagacct aaaaaagata
    11041 ttatatgttt aggtctaaac tataaagacc atgtcaatga aatcccagat ggagttataa
    11101 aaaacgtagt tatgccagat tatccaattt atttttctaa gagagcagac aaaataattg
    11161 gagtggatga taagataagc ttacatggag atttggtaga gaagttggac tatgaatcag
    11221 aacttgcagt aatcataggt aaagaaggta taaatatatc aaaagaagat gcttatgaat
    11281 atatatttgg atatacaata gtaaatgata taagtgaaag agcacttcaa gataaacatg
    11341 ttcaatggtt tagaggaaaa agcttagaca cacatacatc tatgggacct tatatagtac
    11401 ataaagaaga atttgaacat cctttaaaat tagatataag tagtgtagta aatggagaag
    11461 taagacaaaa ttctaataca gagtacttta tatttgatat acctactata ataaatgatt
    11521 tatcaagagg aatgactcta aagccaggag atataatttc aactggaact ccagcagggg
    11581 ttgctatggg gatgaatcct caagtatatt taaagcatgg cgatatagtt gaatgtaaag
    11641 tcgaaggaat aggagtttta aaaaatatag ttgattaatg gataaatatg ccatataatt
    11701 ttattagtac gaataattta attaatatag gattaatcaa acttatgatt aatttattat
    11761 agagagggat gagtatatgg caagagaact agaattaaag tatggctgta atccaaatca
    11821 aaaaccatca aagatttata tgaagaatgg agaacttcct atagaagtat taaatggaaa
    11881 acctggatat ataaattttt tagatgcatt taatagttgg caacttgtga aggaattaaa
    11941 agaagctaca ggtctcccag cagcaacttc atttaaacat gtaagtccag caggagcagc
    12001 agtaggggta cctttatcag atactttaaa gcaaatatat tttgttgatg atttagagct
    12061 ttctccatta gcttgtgctt atgcaatggc aagaggagca gatagaatgt cttcttatgg
    12121 cgattttata gcactttcag atgtatgtga taaggagact gcaactatta tagcaagaga
    12181 ggtttctgat ggtataatag ctccaggata tacagatgaa gcccttgaaa tattaaaagg
    12241 aaagcgtaaa ggcaactata atattgtaaa aatagatgaa aattatactc ctgaacctat
    12301 tgaaacaaag gatgtttatg gaattacttt tgaacaaggt agaaatgaaa tattaataaa
    12361 tgaagaccta ttaaaagata ttccaactga taataaaatt tttacagata gtgcaaaacg
    12421 tgatttaatt atagctctta ttacattaaa atatacacaa tcaaattctg tttgttatgc
    12481 taaagatgga caagtaatag gggtaggtgc aggtcaacaa tcacgtattc attgtactag
    12541 acttgcaggt aacaaagctg atacttggta tcttcgtcaa catcctaaag tattaaactt
    12601 aaaatttaaa aaggatatag gtcgtccaga tagagataac actattgatg tatatctttc
    12661 tgatgattat atggatgtgc ttgctgatgg catatggcaa aacttttttg aagaaaaacc
    12721 agagcctcta actggagaag gaaaaagagc atggcttaaa actttaacag gagtagcact
    12781 tggttcagat gcatttttcc catttggaga taatatagaa cgtgcaaaaa gaagtggggt
    12841 aagttttata gcacaaccag gtggttctat tcgtgatgat aatgttatat taacttgtaa
    12901 taagtataac atagtcatgg catttactaa aaatagatta ttccatcatt aaaatactga
    12961 aagtataaag ataatataga ttaagtaaaa atctacaaca agttttgttg tagatttttt
    13021 tatttgctgt ataattttaa atagaacttt atttttagat attcaatttg gaggttgata
    13081 tggctttaaa tataagaaac tatagcctat tatgtaatca aggaacagct aaatttaatg
    13141 aagatgtagt cggtataaat ccatttggcg catgggtttt agatggtgct acaggactta
    13201 atggaaaaaa tttagtgtca actgaaagtg acgcaaggtg gtatgttcag tggtggaata
    13261 ggtatttata taaaaatata aataaagaag aatcattaaa gagtattatt aatactggaa
    13321 taatagaagt aaaaaaagag tatgaactaa gattaaatgg gtttaaggtt gaaaaattag
    13381 atttaccatc tagttctata gttgttgtaa aatttcatga aaataaagta gagtattttt
    13441 tattaggaga ttgtgctttg tttattaaaa atggagattc caaagttata aaagatagga
    13501 gtatttgtaa atttgataat actgtatttt atgaaatgag taaactttct aacttggaag
    13561 agatggcatt tgatgagatt agaactagtg ttatggatac aatagtaagc aatagattga
    13621 agaaaaatac aaaagagggc tattggatat tggattttga tgaggaagct gtggaaaatt
    13681 ctatatatgg atacattgaa ataaaaaaag attttcaatt gatgctaacg agtgatggtt
    13741 ttacaagtgc atgtgataga tataatctaa taaaagaaga agaattgata cgtatagcag
    13801 aaaaatttgg tataggatat atacataata aagtaaggga ttttgaagat aatgactata
    13861 aagcggttaa agtgccaaga tttaaagtaa aagatgattc atcttgttta tatttagata
    13921 tatataatga ttagactgta taaaactatt taattttaga aaggaggcaa gtgaaaagtg
    13981 aaaattcttc atataataac acaaaaacca aatagtacag gtagtggtat atatttgtct
    14041 ggtatgataa aagggttcga aaaaatcggt cataagcaag ctgtaattgc aggtatagat
    14101 gtaaatgatg atgtaaattg ttttccaagt gaagtaagtt tttatccagt aaagtataat
    14161 tgtggggagt taaattttcc tgttgtaggt atgagtgatt ctatgccata tgaaagtaca
    14221 agatataaag atttaaatat agacatgata aatagattga aatatcaatt taaagtaaat
    14281 atagataagg ctatgaatga ttttaagcca gaacttataa tatgtcatca tttgtacctt
    14341 ttaactgcat ttgttaggga aatggtaaaa gatataaagg ttatgtctat ttgtcatgga
    14401 acttgtttaa gacagttaaa taccattgat ttagagaaag aatacataat agcaaatata
    14461 aggaaattag atttaatatt tgctcttcat gaaaatcaga aatatgatat tataaagact
    14521 tttggagtaa gtgaaagtaa agtagttgta attggtagtg gttataatga tgatatattt
    14581 tataataaaa attataaaat aaaggatgat aaaataaaaa tagtatttgc aggtaagata
    14641 tgtaaatcaa agggactgat tccatttata aaagctatat ctaaattaaa atatagtaaa
    14701 gatttaatag aagtcaattt tgcaggtact ggaagcgata tcgaatcata taatgagata
    14761 gttaaactgg caagtaagtc tccatttaaa atgaatttcc taggaaagtt agaacagaga
    14821 gatttagctg agctattcaa caggtcacaa atatttgtgt taccatcatt ttatgaggga
    14881 ttaccagttg tagttttaga agctttatct tgtggcacag atgtaatcac tactgatatt
    14941 cttggtgtta aagagtggat tggtagtgag attaataatt ctggaaagat agaatatgtt
    15001 tctctacctt ttatggagaa agaaggtatt ccaaaagatg aagagttata tgattttgaa
    15061 aataatttgt ataatgcaat agattctaag atacaatctt tattgaataa ctcaaataag
    15121 aaaacatctg tagatatgtc aaaaaaaacg tgggatggct tagcatatag aataaatgaa
    15181 gttattttaa tggatgaatt gtgtttagtc taaaattatt taaattataa aaaagtgtaa
    15241 ctatttttac actattttta aatgatttta tattatacta atactaaata tatttgtttt
    15301 agggaggtaa tttatgagga ttagtaaaaa ggtattggcg ttaggtattt cagcattact
    15361 gttaagtgtt agttttccaa catcaataaa cgcactagat aagattgaaa atattcaagg
    15421 agtagataaa tatgaaacag ctgggcttat ttcagataag caagatttta caacagcagt
    15481 tcttatcaat gcagactcta caatggtaga tgggattgct gcaagtggtc ttgcaggagt
    15541 aaataatgca gctattttat taactaataa ggatgatata ccagaagcaa cgcttcaaag
    15601 actgaataga gttactaaga tatatgtaat aggtggagaa aattctataa gtaaagatgt
    15661 agaaaaaatg ttacttatga gaagaatgca agttataaga attgatggtg tagatagagt
    15721 agatacaagt tataaaattg caggcgaaat agaaaaaatt aaaaacagtg ataagatgtt
    15781 tttagtaaat ggatttaagg atgaagctga tgcagtaagt gttgcatctg ttgcttatag
    15841 agatggagct cctataatat tgacaaaaga tataccttca gcagaagaag acacagactt
    15901 agacccatgg tttggagttt ctcctgttcc agtatatgct attggaggag agtctacatt
    15961 aagtgattac atagtgagca gatatagagc aactagaatt ggcggtgttg atagatatca
    16021 aactaataaa aatgttattg aaaagttcta taatggagca aaagagttct atataacaag
    16081 tggagacgat ttagtttatg ctttagttgc atcaccactt gcaaaaaatg ctcctgttgt
    16141 tttagtttca aataaaagtg ataagagtat attaagtgga gctagtaaag taacagcaat
    16201 aggtataagt gataagagta ttatagagca atgtttggat gctgtaaaga agtaatggag
    16261 tgttattagt aaaatgaata tacacattga aaattagtag attgttcatt ttataatggt
    16321 ataaaatata tgggaagagg ctatcaaatg gagataagcc tctttttcat tgttaaaatt
    16381 atgaaaagat actttatttt atataaaaaa gtatcttatg aactaaatgt ctattttgag
    16441 acactatcta cttttcttat attatattat tttttatatg gaataaattt cataagtatt
    16501 atcttccttt aatttttcta accaaaccat ctctaaaata tctagttctt ctaaataatc
    16561 tttctctgtt ttgttatcat catgttttat aagttctaaa acttcaaata taaatgcttt
    16621 ttcaccatat tttttccatt cattatttaa ttcttttatc atacatgagc cagcaccaag
    16681 ctgaaatttg agagagttaa atttgctttt tatgtcatta ctttttccaa ggtaaatctt
    16741 tttagtaata tcatttttta ttatgaatac acctatgtca aatttcattt ctttgtataa
    16801 ttgttttaat tcacgttttc tatccatgat tttagatacc tctctttata attgatatgt
    16861 aatatgtaag tgtaaaaata tattacatat aaattataaa gagattaatt ttatatgtaa
    16921 atagttttta taaatttaat tatgaattag tcatcaataa acaagaaatt tagctgtaga
    16981 aatccattat aaaggctatt ataaatttta atatgctaaa aatataaaaa gaatagttga
    17041 cagtgtagaa aatatggaat aaactaaaag tgtaatagta atatgaaatt atatattaca
    17101 ttgaaaggtg tgaatgatta ttatgaataa aaaaatagaa ttaataggga actttgcaag
    17161 tgattggatt aggtatagtg attatgaata taaaattact gaagaagatg aattatatat
    17221 agttccaaca gaagatgctg tgtttaccat gtataaccca tttgatgtag cagatgatat
    17281 aatagtagat ataattcgca taggacaaga ggcattacaa gatatatcaa aagagacaaa
    17341 agaaatgaaa ctaaagaaag aagtacttga atttgtaaaa aagtatggat tattgggttt
    17401 aatatattca agtgtatata atagagatat agttggagaa gaaagagtac tgatgattga
    17461 aaagaattat attacaaaag agaatatatt gagtacagat gaatatgtaa acatgtttat
    17521 accatttgca agtgatgaag atgtgtattt taaaaagtat agaaggggta tagatgtatc
    17581 aaagagagaa gaatctccaa agttttttgg aaagagacca ttgattttag atttagtatt
    17641 ttcaaagttc tacactgaac aactagattg gattgtaagt tttgctaaag atatgtgtaa
    17701 gcattttaat caaatttgtg tatataaaaa tacatctaat ctattaactg aaagtgttac
    17761 tattatgtct ggagggttta atcctcaaaa gataggattt tctataagcc aattagataa
    17821 accaattatt gcatgggagt ttgattcttt gaaaacagct attgagacta tctatgcctt
    17881 tgcaattaca agtgaacctt cttctttaaa taaatgcaag tactgtggta aaatttatat
    17941 tcctacaaat tctaaatctc aatactgttc accttcttgt agaaattgct caaatgtaaa
    18001 gaaaagtaga agtagagcca aaaaagataa ataaaattaa taaatatatc attgtttaga
    18061 ttttagtaaa taactactga attaaaagtt gttatagaaa attatatatc taaatgatgg
    18121 tatttttttt gttgagaaaa ttgaaaagtt taattgagat agtaattttg agttgacaaa
    18181 aaccactttt aacactacta ttataagtgg ttggcaaaat aatatatact aatttaagta
    18241 tagcgtaaaa aacaaaaaaa gtcaatggaa aaaataaaaa aggagaattt aaaaatgata
    18301 tcacctatta ttttgagttc tataaatcag aatttaaagg aaatagaaag aaatgaactg
    18361 cttgaaacta atatagaatc tggagattat ggtctagctc tttctgaatc tgatgtaaaa
    18421 gatataataa attcgagaga taatacttta aaggggtatg gaagaataga attagatata
    18481 aaagttacaa aacagttaat agaaaatata tatacatcac aatatacaaa tgtggacaat
    18541 tatttagagg ctattaatga tatgcaagaa attttttatt atttaaaaaa tgaaactgat
    18601 gacaagatat gtgatgatga gattatagaa atactgggtg aattttatga aaaattttca
    18661 ggcaatatgg acaatgtaag aggagaagca gacgaatttg caaagaaatt taaatttgga
    18721 gaagtttaat atatgataag agagattttg tatgttaaat aatttaagta atattaatat
    18781 aaacgaaaat aatttaataa agaaccaata ttccatatct ctacttaagg aatgtctaaa
    18841 ttgtaaagtg atagatgaaa gagaagtata taatatacaa caagaaatat ctctaatact
    18901 tatggatttg attaaaaaat atacaaatgg tcaaagcaca tcagtaaaaa cagaagttgc
    18961 cgaaaaactg ttgatttcaa tatggtatgc tattgatgca tatataaata agcttggaga
    19021 tatagaaaaa agagttgtgg agttgactgc taagaatgtt aaaaaggtgt accttggagg
    19081 cattgaaata ttagaggaag agttagttag gctaaaagat ttttataaac taatgatgag
    19141 tagaaaattg gatactaatt caatagcata taatgatacc ttgatggagt tatcaagttt
    19201 ctttaaaagt tatattgtaa aatttgaagc tcaggacgtt ccagtaagta tagattatcc
    19261 attggcacta gatgatatgg atgttaaggg tatttattat gtgaagaatt atattgagag
    19321 tatagatata gaaaatagat tttgtaacct atttaagaaa aaagatagag aaaaattatt
    19381 ttatgactat ggggtgactt ataaaataga ttgtgatgtt gtacttgtaa atttatttga
    19441 acttattata aataattgta ttttttctac tattttagga aatgaagtga ctaatttaga
    19501 aatttcaaaa tatgagtatg aatttttaga aaaacaattt aaaaatatgt acaataatat
    19561 tactgaagat gaagttatag gctctgaaga aagtaatata attgaattga ttgaagtaga
    19621 tgatagtttt aacactgaag tagatagtaa tttggattat aatgattttg aagaaattaa
    19681 cagagaaatt agaataaata aaaaaataac tttactactt atggaagcaa ttgaagtatt
    19741 aataaaaaga ttaagcatag aagatgaaga tgtaataaga tatattaaaa aatatgaaaa
    19801 gatatttatt gaatctgtgc taagctcaat aaaaagtaac acttttaaaa gtatggtaac
    19861 tgtgagtaaa aataaaaagg aacacttaga agattatatt gttgatgatg aaagtaaatt
    19921 ggatgatgaa tcgtttagag agatattcaa tgagatatta gatagtacat ctataattga
    19981 aaaaataaga ataataaagg aaaatatcaa tgctaaaaaa gactttatcg atattcttga
    20041 atctgaatgt ttatttggag aagagtattt aatgttgttt gcatcattaa gtgaattaga
    20101 attggcaata ttgggtagtg tagtatttta tgaagatatt agaatgagag aaattaatat
    20161 attagaattt atgttaaatg agaaaactga aactacttta tggaagatag agtacattaa
    20221 atttatgaag aggcaaagtg aagataagat atactccata gaagagcata tgaataaaat
    20281 taattaacaa aaaattgtga ataaatagaa tgttagtata taatataatc tgtaaagcat
    20341 atcaaaaata catatatttg gaggaaaatt atgaaagagt atatcataaa taatgttgaa
    20401 gaaataagag aagaattaat tgatttatct aagaaaatat gggaaaatcc agaattagcc
    20461 tttgaagaaa agtatgcaag tagcattcaa aaagaatacc taaagtcaaa aggatttaaa
    20521 attgaagaag tagaaaattt acctactgga tttatagcaa gttttggaga gggtaaacct
    20581 gtgattggca tacttggaga atatgatgct ttaccagagc tatcacaatg tgtaagtgca
    20641 gaaagaaagc cattggtaga aggaaaagct ggacatggat gtgggcataa cctgttgggt
    20701 gtagcaggtg taggagcagt tgtttctata aaaaaattaa tagaagaaaa taaatttaat
    20761 ggaacaataa aatattttgg ttgtcctgct gaagaagaag gtggaggaaa gacagttatg
    20821 tgtataaatg gctgttttga tgatgtagat tgtgcattta catggcatcc ttttgatata
    20881 aatgcacctt ggagaggtgg aagtctggca aacttatctg taaaatttaa atttaaaggg
    20941 ataacagccc atgcagctca agctcctcat aatggtagaa gcgcacttga tgctgttgaa
    21001 attatgaatg ttggagctaa ttatttgaga gaacatgtta ttgactctat aagaatgcac
    21061 tatgttataa ctaatggtgg tggaagacct aatgtagttc ctggatttgc tgaaagttgg
    21121 tactttatta gaggtaaaaa agcaaaggat gcagaacacg ttcttgatag attaataaaa
    21181 gtagctcaag gagcagcaat gatgacagaa actgaaatgg agtataaggt tacagatgga
    21241 atatatgact atataccaaa ccaatgtttg actgatttag tttatgacaa tatggttttt
    21301 gttggttgcc ctaaaaatac tcctgaagaa gaagaatttg caaaaaagtt gtgtgatact
    21361 cttactagag aagaaagatt aggtgtagca acatcattac aaaatgataa atctattgta
    21421 gaaagctata tacacaagga aatagttgac ggtgacaaag ataaaggact agctggttct
    21481 actgatgttg gagatgtaag ttatgtaata ccagtggctc aatttgcaat ggcagcttgg
    21541 cctgttggaa ttgcaagtca tacatggcag tcatgttcat cagcaggttc aaatatagga
    21601 ttttctgcta tgataaattc agctaaagta ctggcttgta gtgcttatga tgtatttatg
    21661 gatactaaaa ttattgatga agcaaaaatt gaatttgata aatcattaga tggacaaaaa
    21721 tttaaaccat tggtataatt ttggtaataa aatatttctg gggggaatag ctatgagaga
    21781 aaaagttgaa aaagtgcttg aggaaaagat aaaaccagta ttacaaagag atggtggaga
    21841 tgtagagctt atagatgtaa atgaaaatgg tgtggtttta gttagactac aaggggcatg
    21901 tagtgggtgt ccaggagcga ctatgacaat caaagctatt attgaaaatg ttttggtgag
    21961 tgaagttcca ggagtaactc aagtattagg tgtttaatag ttagcgttta ttaaatgtat
    22021 gttatacata agtatttaat aaagaagtaa aaaaaatagt gaagcaatat atatgaaaaa
    22081 gtatgagaaa gataataaaa cattatagaa ataatgaaat atttcatatg tatatgaaga
    22141 aataagaaaa aatag
//
LOCUS       DAEOTL010000068        21970 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEOTL010000068 DAEOTL010000000
VERSION     DAEOTL010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21970
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.068"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            712..1983
                     /gene="serS"
                     /locus_tag="KRH82_002850"
     CDS             712..1983
                     /gene="serS"
                     /locus_tag="KRH82_002850"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBG8656118.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            2352..3857
                     /locus_tag="KRH82_002851"
     CDS             2352..3857
                     /locus_tag="KRH82_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBG8656119.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            3971..4669
                     /locus_tag="KRH82_002852"
     CDS             3971..4669
                     /locus_tag="KRH82_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBG8656120.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            4954..6042
                     /locus_tag="KRH82_002853"
     CDS             4954..6042
                     /locus_tag="KRH82_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656121.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            6281..7471
                     /locus_tag="KRH82_002854"
     CDS             6281..7471
                     /locus_tag="KRH82_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656122.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            7562..9064
                     /locus_tag="KRH82_002855"
     CDS             7562..9064
                     /locus_tag="KRH82_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBG8656123.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            9136..10392
                     /locus_tag="KRH82_002856"
     CDS             9136..10392
                     /locus_tag="KRH82_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBG8656124.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            10564..13338
                     /locus_tag="KRH82_002857"
     CDS             10564..13338
                     /locus_tag="KRH82_002857"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBG8656125.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(13403..13588)
                     /locus_tag="KRH82_002858"
     CDS             complement(13403..13588)
                     /locus_tag="KRH82_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBG8656126.1"
                     /translation="MFFISDIYTKSPIKFDTPLQKKAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            13963..15141
                     /locus_tag="KRH82_002859"
     CDS             13963..15141
                     /locus_tag="KRH82_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBG8656127.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      15268..15353
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            15471..18389
                     /locus_tag="KRH82_002860"
     CDS             15471..18389
                     /locus_tag="KRH82_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBG8656128.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKNPGTYYLVEIMAPRGY
                     EKLKDKVKVEIGNEDIGKIVDIGNIENLKQENPPVNPPIPPDTDEPMVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      18575..18660
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            18760..19422
                     /gene="zmp1"
                     /locus_tag="KRH82_002861"
     CDS             18760..19422
                     /gene="zmp1"
                     /locus_tag="KRH82_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBG8656129.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDSINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(19544..20506)
                     /locus_tag="KRH82_002862"
     CDS             complement(19544..20506)
                     /locus_tag="KRH82_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBG8656130.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVVGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(20676..21866)
                     /locus_tag="KRH82_002863"
     CDS             complement(20676..21866)
                     /locus_tag="KRH82_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8656131.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
BASE COUNT         8685 a         2525 c         3730 g         7030 t
ORIGIN      
        1 ttttaattat tgtattgaag atttataagt ataattttat tgattctacc tttttaaata
       61 actgtagatt tattaaagtt atctatgtac tatattaaac aattaagtag ttattaattg
      121 cacttattag tttattaaaa aactatgtat attactttgc agtaagactt tggaactaaa
      181 tctataatag caaatttaaa tttattaaat agattacctt ataacatttc atataaaata
      241 tattgtgaat ctgagaaaat tactattttt ctttgagtat tttttgtaag cagttctaaa
      301 agattcaatt tcatacctat tacttgaatc attcatcaaa ataattctaa tttaaaaaat
      361 aattctatcc aaataataga tatataggac tatgttataa tataaaaaaa tttatataaa
      421 agttaataac tatacaagat tgataaagaa aaagtcaaaa tagataattg attagcaaaa
      481 tagatataat tataatgaag ttaaatctag caatattctc ctaaaattaa atttcattta
      541 tttaattaaa tataatttga caatgggcaa aaaagtgagt aaaatataaa taaaataaaa
      601 ataacaggtt cggataaaga aaaaggtttc ttaacctcaa gcatgaagta tattatctaa
      661 gttatttgag attaagagat aaatccaatc ttaggtactg aggaggaaaa aatgcttgat
      721 ataaaaagaa taagagaaaa tttagattgt ataaaaaaag caatggaaag aaggggcgaa
      781 aaagacttta accttgatga agtagttaag ttagatgatg aaagaagaaa gattcttcaa
      841 gaagttgaag ttatgaaaaa tgaattaaat acagcatcta aaaatatacc aaatcttata
      901 aaagaaggta aagatgtaga aaatgaaaag attaaattaa aagagttatc tgataaaatt
      961 aaggtaatag accaaaatct taaagaagta gaagataaga tggaatacct attaatgaga
     1021 ataccaaatg taccacatcc agaagtacca caaggtgaaa ctgatgaaga taatgttgaa
     1081 gtaagaactt ggggaaagac tactaccttt gattttgaat ctaaggctca ttgggaaatt
     1141 ggaacagaat taggtatact tgattttgaa acagctagta aaataactgg ttcaagattt
     1201 actctttaca aaggattagg tgctagatta gagagagcat tattaaattt ttacttagac
     1261 acgaatacaa aagtaaatgg atatacagaa gttattccac catttatggc aaatagaaat
     1321 agttttttag gtacaggaca gttacctaag tttgaagaag atatgtttaa aatagaaggt
     1381 atggactatt ttatgattcc aacatcagaa gttcctttaa ctaatataca tgctaatgaa
     1441 atacttaaat ttgaacaatt accgataaat tatacagctt atactccatg ttttaggtca
     1501 gaagctggtt ctgctggaag agatacaaga ggtttagtaa gacagcatca gtttaacaaa
     1561 gtagaaatgg ttaaaatagt tgcaccagaa gaatcttaca atgagttaga aaagcttact
     1621 aacaatgcgg aaactatgct acaattattg aatctgcctt atagagtagt aaagatatgt
     1681 acaggtgatt taggatttac agcttctttt aaatatgatg tagaagtttg gatgccaagt
     1741 tacaataggt atgttgagat ttcatcttgt tcaaactgcg aagatttcca agctagaaga
     1801 gcaggaataa gatttaaaag agataaagat tctaaagctg aatatgtaca cacattaaat
     1861 ggctctgggt tagctattgg aagaagtgtt gcagctatat tagaaaatta tcaacaagaa
     1921 gatggttctg tggttgttcc tgaagtttta agaccatata tgggagtttc tgttattaaa
     1981 taagagttaa attatgtatt tttaagcaat acaataatat agaggtaata aaaaataatt
     2041 aatataaaag tgatacttct aatatagaag taataaaaaa atagttaata taaaagtgat
     2101 acaataatat agaagtaata aaaaaaaagt taatataaaa gtgatacaat aatatagaag
     2161 taataaaaaa tagttaatgt aaaagtgata caataataat agaagtaata aaaaaaaata
     2221 attaatataa aaatgtgtac aaactaatga atattgatat agtaagctat catatgaaag
     2281 agtatgtaca catttttttt actaattttt cacaatatga acataaataa tttataggaa
     2341 aggaatcttt tatgaaaatt caaaatactg agtggggata tattgaatgg aaacatactt
     2401 atgatgaaaa taatccaaaa caagctatga atatatacat tgcagtaact atgcctggta
     2461 agaaacattt taatcatgtt cattatggtc aagagcagat gatatatatt ttagagggag
     2521 agggtttgta tattataaat ggagtttgga agccatttta tcaaggtatg attttttata
     2581 tagaatctgg tagcacacat gaaactataa atacaggtga tagagaaata aaagaactta
     2641 ttgtttcaaa taatgtagat gatgtaggag agagtgaagt tatagatatt aatcctaata
     2701 attatttaaa gaagaccttg ataaattata gtgaaagtac attaaatttg tatgcagcag
     2761 tagaatcaat tcgtggtcaa tttatagacc cgtttaaaat tccattaatt atatatgatg
     2821 attcatggaa tatagtttta aaaaatcctt attttccact tttttgtttt gaaaaatgta
     2881 atcctatgaa atttcctcaa aattgtgatt gtatgaatca aaaaagtagc aatcaatttg
     2941 tatgtgaata tgggataact atatataata taccaatact gtacaaaagc aatagcatag
     3001 gtgttataag aggagggtat gtactattat ctgatttgaa tttagataca gagcataata
     3061 atttatatga tattccagag ggagctgcta gaagtataaa acgcctcctg aaacaaatat
     3121 ctaaaaatat aataaatttt tgctctttta atgatataag aaaggattta caagaaaaag
     3181 agaagactat agcaagaaca tatcattatg gagagcaact tgaaatgaat ttaaaagtag
     3241 ctcaagatat ggttactaat ttaagaataa atcatcactt tttatttaat acattaaatt
     3301 caatggcaag catagcacta gatgatggta gttatgattt gtatagtgca ataatagatt
     3361 tatcaagaat gtttagatat acaatgaggt ctgatttaag atttgtagaa ttagaatctg
     3421 aaatattata cattaaaaat tatttgaatt tacagaaatt acgttatgga gatgcactta
     3481 aagtaaaata tcttattcca gagaagttat ataacctttc tgtgcctttt aactttattc
     3541 aacctattgt agagaatgca tttacacatg gatttagaga tattgacaca gaaaagcgaa
     3601 ttgaaataat tgcaagatta gattctcagt atgctattat agagattcat aataatggaa
     3661 ctatcttaga tggaaataat atagacaaaa taaaggcagg tattcgtagt aataatggtc
     3721 atggtttgtc tttaatatat acaaaattca catctgctta tggaaataat tttgatatgg
     3781 atataaagtc gagtgataat gaaggaactt acataatgat taaaattcct attgaaaatt
     3841 ataaggagta tgtatagaac ttgtgaaaaa ttaataagtt ttataaatgt taagaaatat
     3901 attagatgtt tttatgttgt tttatatatc ttactttttt atattattaa gctaaaaggg
     3961 aggtattctc atgagaagag cactaataat agatgatgaa gaagctgttc taaaaataat
     4021 aacacatttt atagaaatga aagatatgcc aataaaaatt gttggtaaag caacatctgg
     4081 tgatgaagca gtagataaaa tcattggttt agagccagac atagttttta tagatattca
     4141 aatgccaata tacaacgggt tagaagtaat agaaaaaaca tctcatttat ctaaaaaaat
     4201 aaactttgta gtaataactg catttaacta ttttgaatat gctcaaaaag ctttgagatt
     4261 aaatgtaaaa gatatactcc ttaaaccatt ggatatgaaa gaatttacta agtctgtaga
     4321 aaaaattatt ggatatcaat ataccaataa tgatttatta aatgagatac tggaatatat
     4381 aaatctaaac tatagcaatg acttaaagtt aaatgattgt gctagattat ttttaaccaa
     4441 tccatctaat atatctagga tttttaaaag taatttaaat acaactttta tatcatatct
     4501 aaatcatata agaatagaaa aatctattga gttacttgaa aatactacaa aaagtataaa
     4561 tgagattgca gaaatagttg gatataatag cctaaataac ttttataaaa actttaagat
     4621 agaaaaagga atgactccaa aagtttataa actgaacact aaaaattgaa attgataaat
     4681 aaaaagtcaa tatagataat tgtttgagtg tgtctgaata agtatacttt aattatgata
     4741 aaaattaaag cgctttaaac atatttaata atattaaacc ttataaaagc tgtacctatt
     4801 tatataaaaa aatatatata aataaaaaga aaaagatata caaaataaaa aaagtgaatt
     4861 aaatactgtt tcaaaaagac agaattttca tttaatttac tgagagttta tatttcttaa
     4921 aggaaggtaa ctttataatg gaggtaattt aatatgtcag acaaagtgaa tatgaaaaat
     4981 attatctgta ttgcaggcgc ttatctagca acagcaattg gttctgggtt tgctactggt
     5041 caagaaattc tacaattttt tgcctcacaa gggtatatgg gtttaattgg agcattaata
     5101 tcaatggtat tgttttcatt tcttggtgct gaagttataa ctagaggtag agaattaaaa
     5161 cttaaagaac caacaagaat ttacactttt tattgtggga agattttagg aaaattttac
     5221 gaatggttta gtccaatatt tttatttggg attcttatag taatgatttc aggtgcaggc
     5281 tcaactttaa ctgaatacta tggtataaat ccttacttag gaagagtatt gatggctgtt
     5341 gctactttaa ttacagtgtc tatgggttta gaaaaattag taagcatact tggacgtatt
     5401 ggaccagtga tagcagtatt tacaattgct gttggattaa taagcttgtt taagcatttt
     5461 gacggtttat ctatggttgg agaagctatg aaaaatattg aagttacaaa agcatcagaa
     5521 agtccaatcg tttctggtgt aatatataat acattaaata ttattgtaat gattgttttt
     5581 ttaacaggaa tgggagcttc tattgaaagt aaaaaggatg ctttttgggg aggtttatta
     5641 ggtggaatag tgtttatgac tgctggtata gttatgtatt tggctatgat ttcagatata
     5701 ggaaatttgt atatgaaaga aataccatca ctttatttag cagataatat atctccgatt
     5761 gtaggtgtat gtttttcagt tgcattaata ttaggtatct atacaacagc tgttccactt
     5821 ttatggtctg taaccaatag aattgttgaa gatgaacatc ctaaatttaa attggtaaca
     5881 acagtaatag ctattttggc ttgtatagga ggttttttac cgtttggtaa attagtaaac
     5941 attttatatc catatacagg ttatatgggg cttttaattt tagtctgtat ggtgtataaa
     6001 gcaattacat gtagaaaaaa atcaacacaa agtcaggaat agagccactt attaatagtt
     6061 tttatttaaa aaaatttttt atataatccg aatttaaaaa gtcaaaatag ttaaataaat
     6121 tgcaaaacat gataatatat ttaattaaaa taatatagta aaatataaat ataaactaaa
     6181 attaaattta taaaaaatat ctttataaag attattaact tatataattt gtagttaaat
     6241 tataaaaaat aaaaaaataa aattttggag aggtgttagt atgcatgaac ttattttaat
     6301 ctcagaaaag tataaagaag atattttaga tttttttaca gatattcata tgcaccccga
     6361 attaagtttt aaagaattta ggactacaaa agctataaaa gatttattag tgagtttaga
     6421 catagaaata ttagatttag gaatggaaac aggagttgtt ggattattaa aagggaagta
     6481 tgatggtccc acagtagcac taagaggaga tattgatgcg ttgccaatat atgaagaggt
     6541 tgatattaag tataaatcca gatatgatgg tataatgcat gcatgtgggc atgatataca
     6601 cacgtcttgc cttgtaggat gtgcatatgt attgtctcat attagagata gtcttcatgg
     6661 aaatgtaaag tttatatttc aaccagccga agaagtcaat aaaggtgcga agatgttagt
     6721 ggaacgagga gtaatggaaa atccaaaagt tgatgctata tttggacttc ataatcatcc
     6781 agatatacct tgtggaaaaa taggtgttaa gttaggtggg ttaatggcag cagtagacac
     6841 tattaagata gaagtaaatg gatttggagg tcacggaggt ataccaaaca gaacaataga
     6901 ccctatagta gcatcaagtg caattataat gggtattcaa accatagtaa gcagaaacat
     6961 aagtccatta gaatcagctg ttatatcaat aggtactata aatggaggga ctgcaaataa
     7021 tgtaatttca gaaaaggtag atatgacagg cacatgtaga agctttagta atgaagtacg
     7081 aaagaaaata tcagaaaatt tagaaaatat agtttgtgag atagctcgtg gatatcaagc
     7141 aactgcaaag ctagattatt tatttgattt accagctgtt ataaatagta aagagatgta
     7201 cgcaatagct tgtaagtctg tgtgtgattt gtattcagaa gatgctatag ttgatccaat
     7261 accttctaca ggaggagaag atttttctat attcatggaa aaagccccag gattttttta
     7321 ctggttaggg gtaggcaaca aagaacaaga ttgtatatat cagtggcata atcctaaatt
     7381 taaagctgat aaaaattcta tattggtagg tacaaatgta ctatgtcagt ctgttataaa
     7441 ttatatggat aaattaaaaa ataaaattta agatagagca ttctggagat aaagtttatg
     7501 agggggtatt agtttgagga aaattaattc acaggaaaaa aacaaagata gtggattatt
     7561 gatgagggca ctaaatgttg tagagagagc aggaaataaa cttccagacc cagtaaccat
     7621 atttttatta ctatgtataa ttgttgtaat attgtcagca gttatatcta atttaggagt
     7681 agaagaaata catccttcta caaaagaagt tgtaaaggta gtaaatctac tagagaaaga
     7741 gcagattcaa tcatatttag gtagcatagt tacaaacttt cagtcatttg ctcctttagg
     7801 attagtactg gttacaatgc ttggagcagg tgttgctgag aaatctggat ttatggaagt
     7861 gttaatgaaa aagggtataa gtaaagttcc acaaaaactt gtaactgtag caatcgtatt
     7921 tgcaggtatg ttgtcacata cagcagcaga tgtaggattt ataatattac caccacttgc
     7981 agcacttgtg tttttaggaa ttggaagaca tcctcttgta ggtatgtttg cagcttttgc
     8041 aggtgttgca gggggatttg cagcaaatgt tatgcttagt actacagatg tattgttagc
     8101 tggatttaca ataccagcag ctcaaatgat ggacccatct taccaaggca atccagcaat
     8161 gaatctttat tttgctttta tatcagcgat agttttaact tttgcaggag catttgtaac
     8221 tgaaaaattt atagctcctc gttttacaaa atataatgat tcaacaaatg ataaggatat
     8281 acaggaattg agtgaacttg aaaataaggg tataaaatac gctttattat cattgttagt
     8341 tgtagtagta gtgatagttg ccttatgtat aggtgacaat gcatttatga aagatccaga
     8401 gactggttct atactatcta gtaatgcacc tttaatgaaa ggtatagttc ctataatcac
     8461 tattatattt ttaactccag gattagtgta tggaaaagta agtaagaaga taaaaagtga
     8521 caaagattta gtatctatga tgggtagtag tatgagtgat atgggtggat atatagtcct
     8581 agcatttata gcatcccagt ttattaattt atttaatctt agtaacttag gaacaatttt
     8641 atcaataaca ggagcaaaat tactagcaga gtcggggata cctagctatg gattgataat
     8701 aggatttata ttgctatctg gatttatcaa tttatttgta ggaagtgctt ctgcaaaatg
     8761 ggcgatttta gcacctatat ttgttcccat gtttatgcta ctagacttta atccagcatt
     8821 aactcaaata gcttatcgta ttggagatgc ttcaacaaat ccaataagtc cactttttcc
     8881 gtattttcca gttatattgg cctttgccag aagatatgat aaagatatag gtataggtac
     8941 tgtcatatcg aatatgattc catactcagt ggtatttaca ttaatagaaa taataatatt
     9001 gttactattc atgggtattg gcataccatt aggacctggt ggaggaatat cttacgtttt
     9061 atagaccgtt ataataaatt tatcaatgaa gattaaacta ataaaatata ttctttaatt
     9121 aagaggagga ttattatgtt aaaaacaaca aaaatttcag acccagagtt atacaagatt
     9181 gtagctgatg agttggttag acaagaacac aatattgaga tgatagcttc tgaaagtaca
     9241 gcaccaacag aagtacttga attaagtgga tgtgtattta caaataaaac agaagaaggc
     9301 tatccagggg ctcgttttca agcaggttct gaagaagcag ataaacttga aaccctagca
     9361 ataaaacgtg caaaagaagt atttggagca gaacatgtaa acgtacaacc gtattcaggt
     9421 tctacagcta actattgtgt atattcatca atattaaaac caaatgacac tgttttaagt
     9481 atgcgtcttg accaaggtgg acacttgaca catggtagcg cagttaattt tttacatgac
     9541 atttataaat atgaatttta tggggtagac ccaaatactg gacgtataga ttatgatgct
     9601 cttgaagcaa aggcaaaaga atgtagacca aaacttataa ttgcaggggc aagttcatat
     9661 ccaagattaa tagattatga aagaatatca aaggttgcaa aagaagtagg agcttacttt
     9721 atggtagata tggcacatgt tgcaggatta gtcgcagcga aagtaatacc tagtcctgta
     9781 ccttatgcag attttgtttc ttcatctacg acaaagactt tctgtggacc aagaagtggt
     9841 attgtacttt gtaaagcaga acatgcaaag aaactcgata aaggtgtttt tccaggaaca
     9901 ttaggttcta tacatcttaa tacagttgca gcaaaagcct tttcactatt atatttaagt
     9961 acagataaat ttaaaaagat aatggagcaa gttgtagtaa atgctcagac tctagcttct
    10021 gaactgattt cacatggttt tagtattgta agtggaggta ctgataatca tatagtaatg
    10081 gttgacttaa gaagtaagaa tcttacagga aaacaatttg aaaaagctct tgaatatgta
    10141 ggaataacag ttaataaaaa tgttatacct gacgacccac aatcaccatt tgtaactagt
    10201 ggtgttcgta taggtcttac atcaatatct caaagaggtc tgaaagaaaa agaagttata
    10261 cagatagcag ggataatgaa taaggtagca gaaaatattg ataataaaga agtattagat
    10321 gaatgtaaag cagaggcaca agaacttata tctaagtttc cattatatcc agaagggtat
    10381 tttgaagatt aaatattttg atttgtatag ctcacaattt ataaagcctg taacataaaa
    10441 tttaataata tataaccact ataaggtgtt gattaatcaa caccttattt tttttgaaaa
    10501 gtaatataca agctatcata agcatataat tccttataga taattaacaa gggggataaa
    10561 gttatgaggt attataataa acctaccaaa gaagtattaa aatacttaaa aacaaatcca
    10621 gaaattggac ttgatgataa tgaggtagaa gaaaggaagc ttagatatgg attaaatgaa
    10681 tttactataa aagaaggtag aacattttgg gacgagttgg gagaaagttt gacagaacct
    10741 atgatattaa ttctcatagg agcagcagta ataagttctt ttgtgggaga attacatgac
    10801 gcattaggta ttttaggggc tatttttatt ggaatttcta taggcataat aactgaagga
    10861 aaatctaaaa aagcagctca tgccctgtca aaattaacag aaaatataga agtaaaggtg
    10921 cttagaaatg ggaagataat taaaatatca aaaaatgatt tagtaccagg agatattgta
    10981 tatatagaaa ctggggatat gataccagca gatggaagac ttatacagtc tataaatttg
    11041 aaacttagag aagatatgct aacaggagaa tctgatgatg tagctaagaa tgctgatgct
    11101 gtattagata tggaagtagt ttattctaaa acagaaataa tcgaacagga tgcaatacct
    11161 gcaaagcaag tcaatatggt atttggaggg actcttgtag catatggtag gggcataatg
    11221 gttgtcactc atactggtga taagacagag atgggtaaga tagcacagaa tttatcaaat
    11281 gaagaccagc aaactccact tcaaattaaa ttagggaagt tgggtgctaa aatagcagga
    11341 atatcaggca taatagctac tttattgtgt atgtttatga ttatacagat gcagagaaaa
    11401 ggtatgttaa ttttagatac aagcagtgta ttatctttct tacaatcatt agaacctgct
    11461 aaaaatgcat atatggtttg tattgcatta atagttgcaa ctgttccaga aggtttgcca
    11521 actatgataa atattacctt agctataaca atgcaaaaga tggcaaagat aaatgcatta
    11581 gtaacaaaga aagaagcctg tgaaactata ggttctgttt ctgtaatatg ttccgacaaa
    11641 acagggactt taacacaaaa caaaatgatg gtagaggtag catatgttga tggtaaatat
    11701 ataagtggag gagagtatca aagtaatagc tattttgaac aaaactgtat agtaaattca
    11761 actgcagata tagaaaaaga agataattca tttaaatata taggaagcgc aacagagtgt
    11821 gcattacttt tatatcataa tgataagaac tataatgaaa tgagaaaaca aacgtatttg
    11881 atatcacaaa taccatttag ttcagaagaa aagaagatgt caacattaat tcgtcaagag
    11941 gattcagata tattactttc aaaaggtgct ccagaagtat tattaaaaaa atgttcttat
    12001 gtacaacaag gaaaaaatat tgttccaata actccaaaag tagaaaaaag tattttagat
    12061 gagattaaga agttacaaat taaatctatg agaacattag gatttgctta taaaaaaatg
    12121 agtaattcta aaacagaagt tgcaatgact tcagaaggtg aattgaattt aataggaaat
    12181 tcaagaagtt atatgaagga agataattta gtttttagtg gatttgtagg aatagtggac
    12241 ccattgagag aaggggtcaa agattccatt gataaagcat ttaatgcagg agtagatgta
    12301 aaaatgctta caggagataa tataaataca gcaacagcta ttggaaatga attaggacta
    12361 ttaaatgatg ggaaaaaggc agttgaagca acatatatag atgtattgac agataaagaa
    12421 ttgagagaag aaatcaaagg aatatctatt gttgcaagaa gtaaaccaga tacaaaaatg
    12481 agaatagttt cagcacttca aaaaagtggc gaagttgtag ctgtaacagg tgatggtata
    12541 aatgatgccc cagcacttag tcaagcagat gttggaattg caatgggtat ttcaggaaca
    12601 gaagtatcta aaaatgcagc agatataata ttgactgatg atagctttag tactatagta
    12661 gagggaataa aatggggaag aggtatatat gagaactttc aaagatttat acagtttcag
    12721 cttactgtaa atatagtagc atttataatt gctataatat ctcaacttac tggtaaggat
    12781 atgccattta ctacaataca attattatgg gtaaatataa taatggatgg tcctccagcc
    12841 ctagcattag gattagaacc tgttagagat tatgtattga aaagaaagcc aataaataga
    12901 cattctggaa taatagctag gtctatgttt gtaaatatta ttataaatgc tattcttata
    12961 attacaattg tatttactca atcagctttt aatatattgg gagctacatc agaagaacaa
    13021 ggtactgtta tattttcttt atttgcattc agtgcccttt ttaatgcatt aaattgtaga
    13081 gagtttggtt taaatagtac aataccaaat ttctttaaaa ataaactagc attgcaaata
    13141 atagtagtta cagggataat tcaaataata tttacacaag tgttccagag tttctttaat
    13201 tctgtttctt tggactttga tatgtggata aagataatac tatttgcatc cactatccta
    13261 ttgtcaaatg aatttgtaaa gctaattctt agaacaatga aaaatagtag aactatgaac
    13321 tttaatagta aaaattaatt cttatgaaac cgtaaagtac tatatattgt aactttgcgg
    13381 tttttgtttg tttaatgttg ttttatatta ccattttcat atttaatttt ttattaatct
    13441 gaacacaatc ttccattgta attgcttcat ctgtgtcaac acattcaaag tcaatatcta
    13501 atttttgtaa tattttgtat gccttttttt gcaaaggagt atcaaattta ataggtgatt
    13561 ttgtgtaaat atcactgata aaaaacatga tttatttcat tcctttccat ttaaaatctt
    13621 atagttatag tgtatcataa ggttataaaa tatagataaa tatagtataa atttaaaata
    13681 tgtacagaca aaacaaaaaa atcatattct aagtaatact tgggaaaaat gatattatca
    13741 taataaataa tctttgtaaa aacttatata gaatctatta aacagacact aagccataaa
    13801 aactttacta aatataaaat tcgtatctaa atagatatat agaataatat tttactgaag
    13861 tagagtgatt tttaagaatt ttatatataa attatgttat cataaataaa gagatagatt
    13921 ataaaatttg ttaataaaat aaagggcagg gaggtaagtt tcatgttttc caaaatccta
    13981 gtcaaaacat ttattagaga tagcgaaaac gttcaaaata cagatgttag aaataagtat
    14041 ggttatgtag ctggtgtagt aggtatatta tccaatttac ttttatttgt gataaaggta
    14101 ttcataggaa tgctcacatc tagtatagct ataatggctg atgcatttaa taatctttct
    14161 gatatggcat cttcagcaat aactatgata ggttttaaat tagcaagtaa gccagctgat
    14221 aaagaacacc cttttggtca tggaagaata gagtatttat cagcattaat agtagcattt
    14281 atggtgatgt tggttggact tcaatttgta aagtcatcta tagaaaggat agtaaatcca
    14341 attcctgtaa aatttgaagt aataccactt atacttttaa ttgcatctat aatgattaaa
    14401 atctggttga gtcgttttaa taaatttatg ggaaataaaa ttgattcttc agccttaaaa
    14461 gcagtttcac ttgatgcttt aggagatgta tttacttcaa gttgtgtagt tatatcattt
    14521 attgtagcta gatttactaa ttttcccata gatggatatg ttggtatcgt agtatcatta
    14581 gtgatacttt atgctggttt ctctcttgta aaagatacta taaatcctct tttaggggaa
    14641 gcaccggatg aagaaatggt aaattctatt atagagctat tgttatctta taaatatata
    14701 ataggtacac atgatttaat tattcataac tatggagttg gtagatgtat tgcatctata
    14761 catgcagaaa ttccatccaa catagatata atggaaatac atgaaattat agatactgca
    14821 gagagagaaa tatctgaaaa attagatata tatctagtaa ttcacatgga cccaatatgt
    14881 cttgaagata aagaagttat gtcagccaaa aaagaacttg aagaaatact taagaaaaat
    14941 agtcttgtaa aatctatgca tgattttaga atagttggaa aaggaagcaa gaagaattta
    15001 atatttgata tagtagttaa tccttccgaa ttttccaaaa acatgtcaga agatgactta
    15061 aaagaagata taacaaaatt agttaaggag ataaatcctg aatataattg tgtaattgtt
    15121 gtagacaagg attttattta attattaatt aatctcatca taaggtaaaa aatgtaaaaa
    15181 ggatagacaa tagtatagag gcataatata atagaagtat ataattgtat ttttaatata
    15241 aataaagcaa ttttaattgt ttttatgaaa tattatagag atgttgaagt atattctatt
    15301 attgggcacc ttatggatat actgagtcag tggtgcaacc ggctatgaat ataaatttat
    15361 ttattttcat agcttttttt gtataatttt ttagtaaaaa ttactttata tacgatatta
    15421 atggaagatt agattataaa ttataggtaa cctaaagggg tgagatttac atgaagaaag
    15481 gaaatagaaa ggcattatta attagtttaa ttatgatttt aagtatggtg gtgtctacaa
    15541 tatatccaac tgtatcttat gcttcggaat taggagagaa tagtcagatt caaagtggtt
    15601 caactaattc atcaactgga gaggagaagg aaagcgacaa taaaaagcca gaacagactc
    15661 cagagaaaga taaggcaaca gataataaaa aaccagaaca gaccccagag gaagaaaaac
    15721 caacagataa taaaaaacca gaacagaccc cagaagaaga taagtcaaca gataataaaa
    15781 agccagagca aactccagaa ggagaaaagc caatagataa taaaaagcca gagcagatac
    15841 cagaagaaga taagtcaaca gataataaaa agtcagaaca agctttagaa gatgaaaaac
    15901 cactagataa taaaaataca gaaaaaactc cagaggaaga taatctatta gaagatgaaa
    15961 atttattgaa agttttagaa gaagaactta atgaagaaaa tgaagactat ggatttgttg
    16021 taaaaattaa taacaataca atagaaacag aatcaatgaa aaaaatatca tttaatttaa
    16081 cttatactcc aacatcaaaa ggaatacaag caggagattc aataactttt aaggtgccag
    16141 atgtattcaa taaagttaat ttagattata caagtgaatg ctttgataaa acagaaagta
    16201 atggagagta tacacttaca tttagagaat tacctaatgg ccaaagtgta atgcaaggta
    16261 aaataggttt ggaagcatat gttaaaaagg ttgatgaaga tactaatgca aaaatacata
    16321 ttgaaactac tggaaaaata gaaagtggaa gtggagatat agatgtagaa ataaaacctg
    16381 gagataaaac ggatgttcca gatgctaaag gaacacttaa aaagcttgtt gaaggaaaaa
    16441 aatcaactac tgtatttatg ccagttaaaa ataaagatat aaattacagt atacaagtaa
    16501 atgaaaagca ggaagagtta aaagatatta ttttgtatga tgagcttcct gaaggattga
    16561 cattgataaa tggttctgta agtgtagtaa caagtgatgg aaaagaagtt agtgatttta
    16621 atattgaaca gagtaaaaat tctatttcag ttaattttgg aaatatagat aaatcgtata
    16681 ctgttaagta taaggctaga atcagtgaca aaaatgcaaa acatggtaat aaatataaga
    16741 atgtagctag gattgaatct gatggtaaga agatacaaga agatgatgct actgtaagta
    16801 tatttgatag aggagatgat tatcttctta ctaaaggaca ttcaggagca acaaatatta
    16861 ctcaagttgg tcaagtaata aactatcaga tttcaataaa tgatgataaa tcaccaataa
    16921 gtaatgttgt tataacagat aatataccag aaggcatgag attaactact tcaggagaag
    16981 ctgggcatga ttttagagtt gtagaaattc caatgaatgg gagctggact ccttggagta
    17041 aagaaaaaat tgccaataat atttcatata aagtagaaga aaaaagaaat gaaagtgggc
    17101 aagtagataa agttataact ggatttacaa ttaatctcag taaagaagaa gtggaatcaa
    17161 agttttttat agcttataca ttaaaggtaa ttagtattga agatagctat ataaatagag
    17221 ctgttcttga tgcaaataat agtgaaattg ataaaaatga tgagataaac tttaagaaaa
    17281 attctggatt aataagcgca aaaaaagaag ttgataaaaa agttttaaac agtagtgata
    17341 accagattgt taaatacaaa atcaatatgt caacttatgg agtttatgat gcaggacaag
    17401 taaatctttt agatgaagta aactcagttc tagaaatatc taatataaaa tattctgata
    17461 atcttgaact taaaaaagaa gctggagatg gaaaaaatac aataagatta gtaaataaat
    17521 acgaatttaa acagataaaa gaaggggaac ctgtgcaaag ttgggttaca tttgatgcaa
    17581 acttcacaaa tgtaaaagtt ggggagacta tacgaaatgt ggctcagatt aatggttcaa
    17641 gtcctccagg agtagagact actaagcaag gttatgcttt tgaagctaaa aaagtggatg
    17701 ctttagataa aaatgtactt tcaggtgcta agttcaattt agaagatgca tttggaaata
    17761 tagtagttaa ggatttagtt agtgatgaag atggtataat tcaatctagt gtaaaaaacc
    17821 caggaacata ttatttagtg gagataatgg ctccacgtgg atatgaaaaa ctgaaggata
    17881 aagttaaggt tgaaattggt aatgaagata ttggtaagat agtagatatt ggaaatatag
    17941 aaaatctaaa acaagaaaat ccaccagtaa atccaccaat acctccagat acagatgaac
    18001 caatggtaaa tccaccagta ccaccaagca cagataaacc aaggaaacca tcaagttcat
    18061 ctgatacaga ggatactata gttataaatc caccagtacc accatcagaa gatataataa
    18121 atccgccaat accagaggta ttgaatccgc cagtaccacc atcagaagag atgatagaaa
    18181 ctcctgttaa acagattatt ccaataccag aagtagtaaa gccatcagtg tcagaagaaa
    18241 aaaataataa agttaaagat gatactttgg taaatccacc agtaccacca aaaacagggg
    18301 atagtactac aattattgga gaaatacttt tggttatagg agctattgta ggacttatcg
    18361 tattaagaag aaataaaaat acaaattaga ccctaacatt ataaaaaata taagttatat
    18421 taaaaaatat cttctaaaac aatatttaat aatgaaaata ttgttagaag atattttttt
    18481 ttgaagattt atgtaaaaaa ataataactt tttagaaaaa agttccaaag ggatatagac
    18541 aattaaaaag atataagcta taatatagat ataaaattaa atgaggcaaa actagggaaa
    18601 cctagtcacg caaagctata ggggctaaag tttagtaaac catgccagcc agttgccgaa
    18661 aagagtaaaa atttcttttt gtatatacaa agatactctt gggtatcttt tttattttga
    18721 aatttattac tcccggccta actcaaagga gggaataata tgagaccaag taaaaaatta
    18781 ttaatagcta taatatcaat attcttaata agttcagttc cagtaagtgc acatgcagat
    18841 agtactacta tacaacaaaa taaagacaca cttagtcaaa tagtagtttt tccaactgga
    18901 aattacgata aaaacgaagc taatgctatg gtaaatagat tagctaatat agatggaaag
    18961 tatttaaatg cattaaagca aaataactta aaaataaaat tattaagtgg aaagttaaca
    19021 gatgaaaaag aatatgctta tttaaaaggt gtagttccta agggatggga aggtactgga
    19081 aaaacttggg atgatgttcc aggtttaggt ggaagtacag tagctcttag aataggattt
    19141 agtaacaaag gtaaagggca tgattcaata aatttagaat tacatgaaac agcacatgca
    19201 atagaccata tagtattaaa tgatatatct aaatcagcac aattcaaaca aatatttgct
    19261 aaagaaggtc gttctttagg taatgtaaac tacttaggtg tatatccaga agaatttttt
    19321 gcagaatcat ttgcatatta ctatttaaat caagatacaa atagtaagtt aaaatcagct
    19381 tgtccacaaa cttatagctt tttgcaaaat ttagctaaat agagttttaa taaatttaaa
    19441 ataaatataa ataaagagat gctattataa tggcatctct tttatattgc gtttaaatct
    19501 aataaatttt gtcttatgta taactatgat agattatcaa ttactactcc ttatacaagg
    19561 cttcaacgtg tttattatgc atttgagtaa ttatcgtagg tataatagaa attattgaac
    19621 caattactat caataaaatt cctacaacca tgtttatagg gataatttct ttaagtatta
    19681 ataatgctag tattggagat attactggtt taaagaagaa tactaaagat gtaagactag
    19741 tagatgtagc ttccattgcc ataaagtaaa gcgcataacc aacacctgta acaaatacga
    19801 atacataaat cataatgggc atattgtgta aggtatatcc actaaaaata gggatatttg
    19861 caaatacatg aagcttattt ttatttaata tatctgcgat aaaattaatt ttagtgagta
    19921 aaaccaatat caacatttcc aaactaccaa atataaagct aaagcaggtt acaactattc
    19981 caccaaattt taaggttttt cttttaccaa atacagtata cattgaaaaa ataatagcag
    20041 aagataatgt taagaatatt ccactaagag ttagttttgt atgcaatgga tttattataa
    20101 ctataattcc aagaacttct aatataagtg aaattacatt gtgcctatat attttttcct
    20161 tcaaaattaa gtaagctaaa agcattacaa agactggatt acaactgaac aaaacagcaa
    20221 ctacagatgc ctttgtgttt agaacagcaa gttgatacaa tgacatactt actactacac
    20281 acataaaacc taaaaatgca aagtatttta agtctgattt tgtaatagaa agactaaggg
    20341 ctcttaatct ttttacagca aaaggtagta agactaaacc gccaacaaaa aatcttgata
    20401 aagttatttg taagggatta aagtcattag tgacagtttt tagactaatt tccattgaac
    20461 taaaaaataa ggtagtcagt attatataaa cataaccttt tttcaagtca aacacctcct
    20521 tgtaatttat attagtacta tagataagaa tattcaagca tattggaata atatggtatg
    20581 tataaaatat agtacataaa attataaact accttaatat agaatgtaag tattctatac
    20641 taaggtagtt aattatttga attactttga tttagttatt ttaaattata taatttggct
    20701 aatttttcaa atgctggtaa agaactttta actttatcat aagatacaca atatgatact
    20761 ctaaaatgac ctggacaacc aaaagaagaa cctggtacta ataataaatt aaattgtttt
    20821 gcatcattgc agaatttttt atcatcttca attggagctt ttgggaacaa atagaatgta
    20881 ccattaggtt taacacaaga atatcccata tcgattaaac tattatatag aaggtcaaaa
    20941 ttctttttat aaatatttac atcaacttct gcatctaaac ttcttgcaat aaccctttga
    21001 aaaagagaag gagcatttac aaatccaagt attctatttg caacatttaa tgaagacata
    21061 acatcatcaa aatcatccat ttgcccatta gcaacaatat atcctatacg ttcaccaggt
    21121 agagataatg atttactata agagtatcct ataaatgaat ttctatagta ttttagtaca
    21181 caaggaactt tggcaccatc ataaattatt tctctatatg gctcatcaga aattaggtat
    21241 atgcttgtat taaattcttt ttgttttgaa tccaataatt ctccaagatt ttttaataat
    21301 tcttcagaat atatgacacc agtaggatta tttggagtgt ttattattaa agctcttgtt
    21361 tttggagtaa tagcattttt tagagcatct aaatctggct caaaagtctc tatatttgta
    21421 ggaacttcta ttaattttcc atcatagttt tctgtataat ttttatactc accaaaatac
    21481 ggtgcaaaag caataacttc atcaccagga tttaaaagag tttttaaaat aatatttaga
    21541 ccaccagcag caccacaagt cataattaaa ttttctcttg taagatttaa tccatctttt
    21601 ttatttatgt gttcagcaat agcatctctt acatcctcat atcctgagtt gttcatatat
    21661 ccatgaacta aatttggaga ttcttcattt aaaatatcat ttataactgc tttaatagtc
    21721 tctggaggtt caacacttgg atttcctata ctaaaatcaa aaacattttc ctcaccataa
    21781 atatcagaaa gtttctttcc ttcttcaaac atagctctta taacagaact atttgcaact
    21841 aaagtttgca ttttattaga tatcatatgt aacactcctt tttatagatt tatattgctt
    21901 atgtatatat taccatattt ttactgaatt tagacaattt tcgaaaaatt acttgtttga
    21961 aaatataaac
//
LOCUS       DAEOTL010000069        21963 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEOTL010000069 DAEOTL010000000
VERSION     DAEOTL010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21963
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.069"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            370..681
                     /gene="rpsJ"
                     /locus_tag="KRH82_002864"
     CDS             370..681
                     /gene="rpsJ"
                     /locus_tag="KRH82_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBG8656132.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            773..1402
                     /gene="rplC"
                     /locus_tag="KRH82_002865"
     CDS             773..1402
                     /gene="rplC"
                     /locus_tag="KRH82_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBG8656133.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1432..2055
                     /gene="rplD"
                     /locus_tag="KRH82_002866"
     CDS             1432..2055
                     /gene="rplD"
                     /locus_tag="KRH82_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBG8656134.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2055..2345
                     /gene="rplW"
                     /locus_tag="KRH82_002867"
     CDS             2055..2345
                     /gene="rplW"
                     /locus_tag="KRH82_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBG8656135.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2375..3205
                     /gene="rplB"
                     /locus_tag="KRH82_002868"
     CDS             2375..3205
                     /gene="rplB"
                     /locus_tag="KRH82_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBG8656136.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3240..3521
                     /gene="rpsS"
                     /locus_tag="KRH82_002869"
     CDS             3240..3521
                     /gene="rpsS"
                     /locus_tag="KRH82_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBG8656137.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3553..3888
                     /gene="rplV"
                     /locus_tag="KRH82_002870"
     CDS             3553..3888
                     /gene="rplV"
                     /locus_tag="KRH82_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBG8656138.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            3911..4711
                     /gene="rpsC"
                     /locus_tag="KRH82_002871"
     CDS             3911..4711
                     /gene="rpsC"
                     /locus_tag="KRH82_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBG8656139.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            4747..5178
                     /gene="rplP"
                     /locus_tag="KRH82_002872"
     CDS             4747..5178
                     /gene="rplP"
                     /locus_tag="KRH82_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBG8656140.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5180..5383
                     /gene="rpmC"
                     /locus_tag="KRH82_002873"
     CDS             5180..5383
                     /gene="rpmC"
                     /locus_tag="KRH82_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBG8656141.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5407..5661
                     /gene="rpsQ"
                     /locus_tag="KRH82_002874"
     CDS             5407..5661
                     /gene="rpsQ"
                     /locus_tag="KRH82_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBG8656142.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5687..6055
                     /gene="rplN"
                     /locus_tag="KRH82_002875"
     CDS             5687..6055
                     /gene="rplN"
                     /locus_tag="KRH82_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBG8656143.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6079..6384
                     /gene="rplX"
                     /locus_tag="KRH82_002876"
     CDS             6079..6384
                     /gene="rplX"
                     /locus_tag="KRH82_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBG8656144.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6414..6956
                     /gene="rplE"
                     /locus_tag="KRH82_002877"
     CDS             6414..6956
                     /gene="rplE"
                     /locus_tag="KRH82_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBG8656145.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            6974..7159
                     /locus_tag="KRH82_002878"
     CDS             6974..7159
                     /locus_tag="KRH82_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBG8656146.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7192..7590
                     /gene="rpsH"
                     /locus_tag="KRH82_002879"
     CDS             7192..7590
                     /gene="rpsH"
                     /locus_tag="KRH82_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBG8656147.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7621..8163
                     /gene="rplF"
                     /locus_tag="KRH82_002880"
     CDS             7621..8163
                     /gene="rplF"
                     /locus_tag="KRH82_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBG8656148.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8199..8567
                     /gene="rplR"
                     /locus_tag="KRH82_002881"
     CDS             8199..8567
                     /gene="rplR"
                     /locus_tag="KRH82_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBG8656149.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8588..9097
                     /gene="rpsE"
                     /locus_tag="KRH82_002882"
     CDS             8588..9097
                     /gene="rpsE"
                     /locus_tag="KRH82_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBG8656150.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9112..9297
                     /gene="rpmD"
                     /locus_tag="KRH82_002883"
     CDS             9112..9297
                     /gene="rpmD"
                     /locus_tag="KRH82_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBG8656151.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9330..9773
                     /gene="rplO"
                     /locus_tag="KRH82_002884"
     CDS             9330..9773
                     /gene="rplO"
                     /locus_tag="KRH82_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBG8656152.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            9817..11085
                     /gene="secY"
                     /locus_tag="KRH82_002885"
     CDS             9817..11085
                     /gene="secY"
                     /locus_tag="KRH82_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBG8656153.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11102..11752
                     /locus_tag="KRH82_002886"
     CDS             11102..11752
                     /locus_tag="KRH82_002886"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBG8656154.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            11753..12499
                     /gene="map"
                     /locus_tag="KRH82_002887"
     CDS             11753..12499
                     /gene="map"
                     /locus_tag="KRH82_002887"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBG8656155.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12521..12790
                     /locus_tag="KRH82_002888"
     CDS             12521..12790
                     /locus_tag="KRH82_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBG8656156.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            12828..13046
                     /gene="infA"
                     /locus_tag="KRH82_002889"
     CDS             12828..13046
                     /gene="infA"
                     /locus_tag="KRH82_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBG8656157.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13082..13195
                     /gene="rpmJ"
                     /locus_tag="KRH82_002890"
     CDS             13082..13195
                     /gene="rpmJ"
                     /locus_tag="KRH82_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBG8656158.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13348..13719
                     /gene="rpsM"
                     /locus_tag="KRH82_002891"
     CDS             13348..13719
                     /gene="rpsM"
                     /locus_tag="KRH82_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBG8656159.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            13755..14153
                     /gene="rpsK"
                     /locus_tag="KRH82_002892"
     CDS             13755..14153
                     /gene="rpsK"
                     /locus_tag="KRH82_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBG8656160.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14185..14808
                     /gene="rpsD"
                     /locus_tag="KRH82_002893"
     CDS             14185..14808
                     /gene="rpsD"
                     /locus_tag="KRH82_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBG8656161.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            14886..15833
                     /locus_tag="KRH82_002894"
     CDS             14886..15833
                     /locus_tag="KRH82_002894"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBG8656162.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            15854..16195
                     /gene="rplQ"
                     /locus_tag="KRH82_002895"
     CDS             15854..16195
                     /gene="rplQ"
                     /locus_tag="KRH82_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBG8656163.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16315..17148
                     /locus_tag="KRH82_002896"
     CDS             16315..17148
                     /locus_tag="KRH82_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBG8656164.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17136..18002
                     /locus_tag="KRH82_002897"
     CDS             17136..18002
                     /locus_tag="KRH82_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBG8656165.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            17996..18799
                     /locus_tag="KRH82_002898"
     CDS             17996..18799
                     /locus_tag="KRH82_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBG8656166.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            18831..19562
                     /gene="truA"
                     /locus_tag="KRH82_002899"
     CDS             18831..19562
                     /gene="truA"
                     /locus_tag="KRH82_002899"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBG8656167.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19682..20113
                     /gene="rplM"
                     /locus_tag="KRH82_002900"
     CDS             19682..20113
                     /gene="rplM"
                     /locus_tag="KRH82_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBG8656168.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20142..20534
                     /gene="rpsI"
                     /locus_tag="KRH82_002901"
     CDS             20142..20534
                     /gene="rpsI"
                     /locus_tag="KRH82_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBG8656169.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            20993..21745
                     /gene="cwlD"
                     /locus_tag="KRH82_002902"
     CDS             20993..21745
                     /gene="cwlD"
                     /locus_tag="KRH82_002902"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBG8656170.1"
                     /translation="MEYYGVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKALSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8821 a         2564 c         4498 g         6080 t
ORIGIN      
        1 ctttactaaa ctaatggatt taatataaaa aaaagagggg gtaactcctc tcttttttgt
       61 tttttgttga caagtagcgc taaagcatat atactaaact agtgccttga gacagattaa
      121 caatcaagtt taaggttatg atgttgtaat agaaaataaa attgaaaaaa acagaaaaaa
      181 aacttgaaaa aatgtaacag atgatataga atataatagt gtgcttgaga gattaagaaa
      241 ataataatta aatcctagtg aaatacgaac tgatatcgat ttaaaagtta caacacaccc
      301 ggagcagtgt atcggtattg gttgtacgca acttgaaaat taaacacgtg ataaaggagg
      361 gaaaacaaaa tggctaagaa tgaaaaaata agaataagat taaaatcata tgatcacaaa
      421 ttattagatt tttcagcagg taaaatagtt gaaactgcta aaaaggctgg atcacaagtt
      481 tcaggacctg tgcctctacc aacagaaaaa caagttgtaa ctatattaag agctgtacat
      541 aagtacaaag actctagaga acaatttgaa ataagaactc ataaaagact aatcgacata
      601 gctaatccaa cacctaagac agttgactca ttaatgagat tagacttacc agcaggtgta
      661 gatatagaaa taaaattata agaaccccta agatattatc ctatagatga ttatcttaga
      721 atgattactc taaaagatgt aatccgctgt aagaattata ggaggtgcta atatgaaagg
      781 aatattaggc aaaaaagttg gtatgactca aatattcact gataaaggtg tagttatacc
      841 tgtaacagct gttgaagcag ggcctatggt cgttactcaa ataaaaacag ttgataaaga
      901 tggatacaat gctatacaaa taggttttga agatgctaaa gaaaaagctt taaacaaacc
      961 taaaaaagga catttagctg ctgctaatgt tttaaagaaa catttaaaag aatttagagt
     1021 agattctgta gaaggataca cagtaggaca agaaataaaa gctgatgtat ttgaagcagg
     1081 tgcaaaaata gatgttactg gaataagtaa aggtaaggga ttccaaggtc caataaaaag
     1141 acatggacaa agtagaggtc ctgaaactca cggttctaga taccacagaa gaccaggttc
     1201 aatgggagct tgttcttacc caggtagagt atttaaaaac aaaaaattag ctggacatat
     1261 gggaagcgta aaggtaacag ttcaaaactt agaggttgtt aaagtagatg ctgacaagaa
     1321 ccttatatta gttaaagggg ctataccagg agctaaaggt tcagtagtaa ctataaaaga
     1381 agctataaag gtttctaaat aatgactaac ctagagaaag gaggaataac aatgccaaaa
     1441 ttaaatgtac taaatgttag tggacaaaac gttggagaaa tagaattatc agattctata
     1501 tttggcgtag aagttaatgg acatgtttta tacgaagttg taaaaaatca attagcaaat
     1561 aagagacaag gaactcaatc tgctaaaact agagcagaag ttagaggtgg cggaagaaaa
     1621 ccttggaaac aaaaaggaac aggtagagca agacaaggtt ctacaagatc tgtacaatgg
     1681 gtaggtggag gagttgcttt tgcacctaaa ccaagaagct acaaatatac attacctaag
     1741 aaggtaagaa gattagctat gaagagtgct ttatcttcaa aagttcaaaa tagtgaagtt
     1801 atagtattag atgcattaaa catggatgct cctaagacta aagaatttgc tcaaatatta
     1861 aacaatataa atgctgctaa aaaagcttta gtagttatag ctgacaaaaa cgataacgta
     1921 ataaaatcag ctagaaatat agaaggtgtt caaactgcat tagttaatac tatgaatgta
     1981 tatgatatat taaaatacga ttcatttata ataactacag atgctgttaa aaaagtggag
     2041 gaggtgtacg cataatgact aatccacatg atgtaataat aagaccagtt gtaactgagc
     2101 acagtatggc tgaaatgggt gaaaaaaaat acacttttgt tgtggctaaa gatgcgaaca
     2161 aaactgaaat aaaaaaagca gtagaaaaag tattcggagt tagtgttgat aaagtaaata
     2221 ctttaaacta cgatggaaaa gttaaaagaa tgggtagaac tcaaggaaga acatcaagct
     2281 ttaagaaagc agtagttaaa ttaactgctg atagtaaaga aatagaattc ttccaaggaa
     2341 tgtagtatta taacaaacga aggagggaaa acagatggct ataaaaaagt ttagaccaac
     2401 ttctcctgcc ttaagacaaa tgacagtttt agtttctgat gaaataacat gtaatcaacc
     2461 agaaaaatct cttttagtta acttaaagaa aaatgctggt agaaacgtac atggtagaat
     2521 aactgttcgt catagaggtg gaggacaaaa aagaaaatat agaataatag attttaaaag
     2581 agataaagat ggtatacctg ctaaggttgc tactatagaa tatgatccaa acagaactgc
     2641 aaatatcgca ttattaaact atgctgatgg agaaaaaaga tatatattag ctccagttgg
     2701 aattaacgtt ggagatacta tattatcagg attaggtgct gatataaaac caggaaactg
     2761 tttagcatta aaagatatgc cagttggtac tatcattcat aatatagaat taaagccagg
     2821 aaaaggagct caattagtta gatctgctgg agtttctgca caattaatgg ctaaagaagg
     2881 aaaaaatgct ttattaagat taccatcagg tgagatgaga ttagtaagca taaactgtaa
     2941 agctactata ggtcaagttg gaaatataga gcatggtaac gtagttatcg gtaaagcagg
     3001 tagaaaaaga catatgggaa taagacctac tgtaagaggt tctgtaatga accctaatga
     3061 ccatccacac ggtggagggg aaggtagatc tccaataggt agaccatctc ctgttactcc
     3121 atggggtaaa ccagctcttg gatacaaaac tagaaagaaa aataaagctt caaataaact
     3181 aatagtatca agaagaacta agtagtaaat ttatttttgc tcggaaagga ggaatataaa
     3241 tgtcaagatc aactaaaaaa gggccttttg tccatgcaag acttttaaag aagatagaag
     3301 ctatgaatgc tagtggaaat aaagaagtta taaaaacttg gtcaagatct tcaactgtat
     3361 ttccacaaat ggtagaaaac actatagctg ttcatgatgg aagaaaacat gttccagtat
     3421 atataacaga agatatggtt ggacataaat taggtgagtt cgttcctact agaactttca
     3481 aaggacataa ggatgacgaa aaatctaata agagaaaata attaaattat gactaagaaa
     3541 ggaggaataa caatggaagc aaaagctact gctaaatacg tacgtgtatc accaagaaaa
     3601 gcaggccaaa tatgtgacct tgttagagga aagaatgttg atgaagcatt agcaatatta
     3661 aagtttactc caagaggagc agcttcaata atagctaagg ttgtaaaatc agctaaagct
     3721 aacgcagaaa acaatcacga aatggatact gaaaaattat atatagcatc aatagttgct
     3781 aatcaaggac caacaatgaa gagattcatg cctagagcta tgggtcgtgc aactacaata
     3841 agaaaaagaa cttctcatat agaggttgtt gttaaagaaa aaaaataatt aatagatagg
     3901 agggaaagta atgggtcaaa aggttaatcc acacggctta agggtcggtg ttataaaaga
     3961 ttgggactca agatggttcg ctactgataa aaaagagttc ggaaacttat tattagaaga
     4021 ccataatata cgtaaattct taaagaaaag attatactca gctggagttg ctaagataga
     4081 aatagaaaga tcagctaaca aaataaaaat ggacttacac gttgctaagc ctggtgtagt
     4141 tataggaaga gctggtgcag gaatcgaagc attaaaagct gaattagaaa aaatgacaaa
     4201 gaaaactata atagttaata tagtagaagt aagaagtaca gataaaaatg ctcaattagt
     4261 agctgagaat atagctttag ctatagagag aagggttgct ttcagaagag caatgaaaca
     4321 agctatacaa agagcaatga aatctggtgc taaagggata aaagtttctg cttcaggaag
     4381 attaggtgga gctgaaatgg ctagaactga aggttatagt gaaggaaatg tgccactaca
     4441 aactttaaga gcagatatag attatggttt cgctgaagct gatacaactt atggaaaaat
     4501 cggtataaaa gtttggatat gtaatggtga agttttacca actagagacg gtgtaaatcc
     4561 aagagaagaa agcagaaaga gcgatagaag agacaacaag agagataata gaagaaacga
     4621 tagaagagga aatgataaca gaggaaacta cagaggacaa agacctcaag gtggatcaag
     4681 acctcaaaga actgaaaaca aaggaaatta ataatagtta ggttcaagga aggaggaaaa
     4741 atactcatgt taatgccaaa aagagtaaag cgtcgtagag ttcatagagg aagcatggct
     4801 gggcaagctc ataagggtaa taaagttact tatggtgagt ttggattagt agcattagaa
     4861 gcttcttgga taacttctaa tcaaatagaa gctgccagaa tcgcgatgac tagatatata
     4921 aaaagagggg gaaaggtttg gataaaaata ttccctcata aaccagtaac aagaaaacca
     4981 gcagagactc gtatgggtgc agggaaaggt tctccagaat attgggtagc tgtagttaag
     5041 ccaggaagag ttatgtttga attagcaggt gtttctgaag ataaagcaag agaagctatg
     5101 agacttgctg cacataaatt accaatcaaa tgtaaatttg ttaaaaaaga agatttagaa
     5161 gtaaagggtg gtgaatagga tgaaagctaa agaattaaga gatttaacaa gcgaagagct
     5221 aatgaacaaa ttaaacgact tcaaaagtga attatttagc ttaagattcc aattagctac
     5281 tggtcaatta gaaaatacag ctagaataaa gtttgttaag aaggatatag caaaagttaa
     5341 aactgttctt gctgaaagaa agttatacga aactagagct taatttggaa aggaggcttt
     5401 ttaaacatgg aaagaggaag aagaaaagtt agaataggcc gtgttgttag tgataagatg
     5461 gataaaacaa tagtagtagc tgttgaagaa ttcgtacgtc atccactata taataaacgt
     5521 gttaagagaa ctaagaaatt caaggctcat gatgaaaaga atatatgtaa catcggagat
     5581 agagttaaaa taatggaaac tagaccatta tctaaagata agagattcag actagttgaa
     5641 gttgttgaga aagttaagta gtttttgaag aaggagggat tacgatatga tacaacaaga
     5701 atcacgtcta agagttgctg ataactcagg agctaaagaa cttttatgta tacgtgttct
     5761 aggcggaagt aaaagaagat atggtaacat aggcgacgtt atagttgcta ctgttaaaag
     5821 tgcaacacct ggtggagttg taaaaaaagg taaggttgtt aaagctgtta tagtaagaag
     5881 caaacaaggc gtaagacgta atgacggaag ctatatatct tttgatgaaa atgctgctgt
     5941 tataataaag gacgataaaa ctccagtagg aactcgtata ttcgggcctg ttgctagaga
     6001 gttaagagac aatgaattca tgaaaatagt ttctcttgct ccagaagtac tataattaag
     6061 gaggtgcaat aggacatgat gcgtgttaaa aaaggtgaca ctgttgtagt tatagcaggt
     6121 aaagataaag gtaaaaaagg ttcagtttta aaggtatatc ctaaaactag caaagtgtta
     6181 gttgaaggtg taaatgtaat aactaaacat caaaaaccaa gtgctatgaa ccaacaaggt
     6241 ggaataataa ataaagaagc cccaatacac atatctaatg taatgccatt tgatcctgaa
     6301 acaggaaaag gcgttagagt aagatatgaa gtaaaagatg ggaacaaagt aagagtatca
     6361 gcaaagagcg gaaaagaatt ataataaata ttgcttgaaa ggagggacct taaatggctt
     6421 ctagattaca agaaaaatac atgaaagaag ttgctcctgc tttaatggag aaatttggat
     6481 acaaaaacgt aatggagata cctaagttaa ataaaatagt tattaacatg ggtataggtg
     6541 acgctagaga aaatccaaaa ggattagaaa aaggcgttga agaattagaa atgatatcag
     6601 gacaaaagcc tgttataact aaagctagaa aatctgttgc taacttcaaa ttaagagaag
     6661 gaatgccaat aggaacaaaa gttacattaa gagctgacaa aatgttctac tttatggaca
     6721 aattagtttc agtttcttta ccaagagtta gagactttag aggagttaac cctaatgctt
     6781 ttgatggtag aggaaattat gctttaggag ttaaagaaca attaatattc cctgaaatag
     6841 aatatgataa aatagataaa gtaagaggaa tggatataat atttgttact acagcaaaaa
     6901 ctgacgaaga agctcgtgaa ttattaaaat tattaggaat gccattttct aagtaagcaa
     6961 aggagggatt cccgtggcta gaaaagcgat ggttgttaag caacaaagaa agcaaaagta
     7021 cgctactaga gaatacacta gatgtactat atgcggaaga ccgcattcag ttttgaaaaa
     7081 atttggtata tgccgtatat gctttagaga attagcttat aaaggtcaaa tacctggtgt
     7141 tagaaaagca agctggtaga agtttgatta gaatggaagg agggcaacaa aatgacaatg
     7201 acagatccaa ttgcagatat gcttactcgt ataagaaatg ctaatgttgt taagcatgaa
     7261 actgtagatg ttccagcttc taatatgaag aaagaattag ctagaatctt attagaagaa
     7321 ggtttcataa gaggttatga tgttatagaa gatggaaaac aaggtatcat aagaatacaa
     7381 ctaaagtacg gacaagaagg cgaaagagtt ataacaggtc ttaagaaaat atctaagcct
     7441 ggaatgagag tttacgctgc taaccatgag ataccaaaag tattaaacgg attaggaata
     7501 tcagttatat ctacttcaaa aggaatatta actgacaagc aagctagaaa agaaaatgtt
     7561 ggtggagaag taatctgcta cgtttggtaa ttaatatgaa caatgtaagg aggtgcgacc
     7621 atgtcaagaa taggtgttaa gccaataata ataccagcag gtgttgaagt tactatagct
     7681 gaaggaaatt tagttacagt aaaaggtcca aaaggaactt taactaaaca attaagtgct
     7741 gagttaaaca taaaaaaaga agaaaataca ataatggttg aaagaccaac tgataataaa
     7801 aaacatagat ctttacacgg actaactaga actttattag ataatatggt tgtaggtgta
     7861 aatactggtt tcgaaaagaa attagaatta aaaggtgttg gatatagagc tcaaaaacaa
     7921 ggaaagaaat tagttatgaa cttaggtttc tctcatccag ttgaaatgga agatccagaa
     7981 ggaataactg ttgaagctcc aaaccaaaca gagttaatag taaaaggtat agacaagcaa
     8041 ttagtaggga attatgctgc taagataaga gcttggagaa agccagagcc atacaaaggt
     8101 aaaggtataa aatacgttga tgaagtaatc agacgtaaag aaggaaaaac tggtaaaaaa
     8161 taataccaaa acttaaacgc tagaaaggag tgagctaggt gttaaaaaag gctgataaaa
     8221 atgctaatag acttcaaaga cataagagag ttcgtagaaa aataagcggt acttctcaaa
     8281 gaccaagatt atgtgtattt agaagtgcta acaatatata tgctcaaata atagatgaca
     8341 caaaaagagt aactctagtt gctgcatctt ctttagaagc agaagttaag agtgctgtca
     8401 atcatacagg aaacaaggaa gcagctaaga aagttggaga attagttgct aaaaaagctg
     8461 ttgaaaaagg aatcactgaa gttgtatttg acagaggtgg atacttatat catggaagaa
     8521 ttcaagaatt agctgaaggt gctagagaag ctggtcttaa gttctaatac gaaggaggga
     8581 aaaatacatg ctacgtcgta agccgataga tgcaggacaa cttgacttac aagaaaaagt
     8641 tgttgaagta agacgtgtta ctaaggttgt aaaaggtggt agaaatttca gatttgcagc
     8701 attagtagtt gttggagatg aaaacggaca cgttggtata ggtgctggga aagcaatgga
     8761 agtaccagac gctataaaaa aagcagttga agatgctaag aaaaatctaa tagtagtgcc
     8821 aatagttggg actacaattc ctcacgaagt acgcggacac tttggtgctg gaaatatatt
     8881 aataatgcct gctgtagaag gtacaggagt aatagctggg ggacctgcta gagccgtact
     8941 tgagctagct ggactaaaag acgttagagc taaatcttta gggtctaaca atccaagaaa
     9001 tatggtaaat gctacaatag aaggacttaa ttctctaaaa acagttgaag atatagctaa
     9061 acttagaggt aaaaaagttg aagaacttct agggtaagga ggtagtgtaa aatggctaaa
     9121 ttacaaataa agttagttag aagtgttata ggaactactc ctaaccaaaa aaagaatgtt
     9181 gaagcgttag gattaagaaa aagagaacaa gttgttgtaa aagaagacaa tgctcaaaca
     9241 agaggtatga taaataaagt aagtcactta ttagaagtaa ctgaaatagc tgaataattt
     9301 ttataaagta gtgcaaggag gtgcaatcca tgaagttaca tgagttaaaa cctgctgaag
     9361 gtgcagtaag agctaagaga agattaggta gaggtactgc aactggacaa ggtaaaactg
     9421 caggacgtgg acaaaaaggt caatggtctc gttctggtgg tggagtaaga gtaggatttg
     9481 aaggtggaca aatgccacta gctagaagac ttcctaagag aggtttcaat aacatattta
     9541 agaaagttta cacagaagtt aatgttgaag ttttaaacag atttgaaaat ggaacagaaa
     9601 taactgcaga attattaaaa tctactaaaa ctataagcaa aataggtaaa gacggaatta
     9661 aaatcttagg tgaaggtaat ttagagaaag ctttaactgt taaagctgct aaatttacag
     9721 cttcagctca agaaaaaata gaaaaagctg gtggaaaagc agagttagta taataacctg
     9781 ctaatctcct agccagtaca ggcggggtga attagcgtgc tgtcaaaatt aaaacaagct
     9841 tggaagatta aagcagtaag aaaaaaagta atgtatacac ttatgatgat cgtgatattc
     9901 agaataggta ctactatacc agttccaggc atagacacta gtattataca aaagatggta
     9961 ggcggcaata gtctactttc tctgtataat atgtttactg gtggagcatt tagtaacttt
    10021 tcactatttg ctttaggtat aagtccatat atcactgcat caatcataat acaacttcta
    10081 acagtaggtt ttgaaagttt agcagaactt caaaaatctg gtgaagaagg aaagaaaaaa
    10141 atcaataagt acactaaata tacagcacta gctctagcag ttgtacaagc tttgggaatt
    10201 acattaggaa ttgtaagaag tgctttaata tcaaatagtg tgttttttat cacaactgtt
    10261 gtaataacat tagtttcagc aagtatgtta gtaatgtgga ttggggacaa aattactgaa
    10321 aaaggaatcg gtaatggtag ttcagtaata atatttgcag gtataatatc aagaatacct
    10381 acagatgtta ttaaaatatc gcaacaagtt aaatctggcg aagttgcacc ttgggttata
    10441 gtgattctag ctgtagttat attacttaca gtaacaggag ttacatttat acaagaagca
    10501 actagaaaga tacctgtaca atatgctaaa agagttgttg gaagaaaaat gtatggagga
    10561 caaagttctc atataccaat gaaagttaac cagtcaggag ttatgcctat aatttttgct
    10621 agttcacttt tagctttccc tcaaacaata gctatgttta tgggtccaaa tgctcaggct
    10681 tttgttcaaa aatacttaag tatggcaaca gaacaaggat tttggacata tagatcaatt
    10741 gagattctac ttataatttt cttctcatat ttttatacaa ctgtatcatt taatacagaa
    10801 gacatatcta aaaatatgaa aaataatggt ggatttatac caggtataag accaggtgag
    10861 cctactatgg attatttaaa tagaatttta actagattaa ctttagctgg agctactttc
    10921 ttagcaataa ttgctatggt gccagctctt acaacacatt atatgaaagt aaatatgagt
    10981 ctagctggga cttcattgct aatcgttgtt ggagttgctt tggagcttaa gagacagtta
    11041 gagtcaaact tagttatgag aagctatcaa ggtttcttaa aataaaatgg agatggataa
    11101 tatgagaata atattacttg gacctccagg tgctggtaaa ggtactcagg cggcaggaat
    11161 agtagaaaaa tacaatatac ctcatatatc aacaggagat atattcagaa agaatataaa
    11221 agagggaaca gaacttggaa aaaaagctaa agaatacatg gaccaaggtt tattagtacc
    11281 agatgagtta actgtaggtt tagttactga tagaatatct caagaagatt gtaaaaatgg
    11341 atttatgtta gatggatttc caagaaatgt agcacaagga gaacatttag atatcttctt
    11401 aaaaaatgct ggtatatcac tagataaagt tgtcaatatt gaagttgata agagtatatt
    11461 agtgtctaga gcagttggta gaagaatatg taagtcttgt ggagctactt accatgttga
    11521 gtttaatcct cctaaagtag aaggtgtatg tgatgtatgc caaggagaat tatatcaaag
    11581 agctgatgat aatgaagaaa ctgtatctaa gagaatacaa gtttatctag atgaaactaa
    11641 gcctttagta gattattata gcaaacaagg tataatagca gatataaaag gtgatcaagc
    11701 aatagataaa gtatttgaag atattgtcgc agccttagga agtggaaaat aaatgattat
    11761 cttgaaatca aaaaaagaaa tagaactttt aagagaagca ggtaaaatag ttgctgacac
    11821 tcatgaagtt ttaagaaaag ctatttctcc gggaatatct actttagaat tagataaaat
    11881 agctgaagag aatataagaa aatacaatgc agaaccttct tttaaaggat atggaggttt
    11941 tccaggaagt atatgtgctt ctatcaatag agaggtagta catggtattc caggagaaac
    12001 tatattacaa gaaggtgaca ttgtaagttt ggatatagga gcctattata aaggatatca
    12061 tggtgattct gcgaaaactc acggagtagg catgatatct gaagaagata ggaaattgat
    12121 agaagtaact agagaaagct tctatgaagg aataaaattt gctaaattag gatatagact
    12181 ttcagatatc tcacacgcag tacaaacaca cgttgagaaa catggtttct cggtagttag
    12241 agatttagtg ggtcatggag ttggagcaaa tcttcatgaa gacccacaag tacctaatta
    12301 tggactccca ggaaaaggac caagacttag agaaggaatg gttattgcta tagagccaat
    12361 ggttaatgca ggtcgttatc atgtaaagac tctatcagat gggtggacga ctgttacaat
    12421 agatggaaaa aaatcagctc attatgagca tacgatagca attactgaac atgaaccttt
    12481 gatattgaca aagttgtaat ttaaaaagta ggtgaaaaaa gtgctatcag ataatttaag
    12541 tataggtcaa gttgttaaag tttcattagg acgagataaa ggaaatttat tctttgtagt
    12601 caaaataatt aataatgaat atgtattaat agctgatgga aaaaagagaa aacttgacaa
    12661 acctaagtta aagaaagtga agcacttaaa aaaatataat tttattaatg atgaagttag
    12721 aaaaagagta gtatctggac aagagattac agattctttt ttaagagctg aacttactaa
    12781 gttaaattag ataatttaac ttattgaaat ggagggctgg ttagttaatg gccaaaaaag
    12841 atgttataga attagaaggt acagtttcag aagctttacc taatgctatg ttcaaagtta
    12901 aactagaaaa tggacatgag atattatgcc acatttctgg aaagctaaga atgaacttca
    12961 taagaattct tgaaggtgac aaggtgaatg ttgaactttc tccatatgac cttacaagag
    13021 gaagaattac ttggcgtaag aagtagacta tattaatatt tagtctaagg agggattaat
    13081 aatgaaggtt agaccatcag taaaaccaat atgtgaaaaa tgtaaagtaa taaaaagaaa
    13141 aggaaaagta atggttatct gtgaaaatcc aaagcataag caaaagcaag gataagaaat
    13201 tattactagc attttgttaa attttatagt ataatactat attgtgatgt taacaaaaga
    13261 acgttaaaat cgttgaacaa tctggcgtag gattggcata tgatgtgaag ttttaaacac
    13321 taaaaactat gtgtaggagg tgcgatcatg gcaagaatag ctggggtaga tttacctaga
    13381 gaaaaaagag cggagatagg cttaacttat atatatggta taggtaaagc aactgctaac
    13441 gaaatattag ctaaggctga gataaatcca gatactagaa taaaagattt atcagaagat
    13501 caagttaatg agttaagaaa agttatagat gacgatttct tagttgaagg tgacttaaga
    13561 agagaaattg ctttaaacat aaagagatta agagatataa aatgttatag aggaataaga
    13621 cacgctaaag gtcttccatt aagaggacaa agaactaaga ctaatgctag aactagaaaa
    13681 ggtcctagaa aaacagtatc tcgtaaaaag aaaaaataaa taaataataa ctagatgaag
    13741 gagggaaaag gaaaatggct aaaccaaaaa agaaagttac acgtattaga agaagagaac
    13801 gtaaaaatat agaacgtggt catgctcata tacaatcaac tttcaataat acaataataa
    13861 ctttaactga cgttcacgga aatgctatat cttgggcaag ttctggacaa ttaggattca
    13921 aaggatcaag aaaatcaact ccatttgcat ctcaaatggc tgctgaaaca gctgcaaaag
    13981 ctgcgatgga acacggacta aaaagtgttg aggtattcgt aaaggggcca ggttcaggaa
    14041 gagaagctgc aataagagct ttacaagcaa ctggactaga agtaactatg ataaaagacg
    14101 ttactccaat cccacataac ggatgcagac caccaaagag aagaagagtg taattaataa
    14161 gagtacaata ggaggtgtag ataaatggca agatatacag gtgcatcatg tagacaatgc
    14221 cgtagagagg gaatgaaatt attccttaaa ggtgatagat gttatacaga caaatgtgct
    14281 atagtaaaaa gaaactatgc tccaggtcaa catggccaag gaagaaagaa agtttctaac
    14341 tatggattac aattaagaga aaaacaaaaa gttaaaagaa tatatggagt tttagagact
    14401 caatttagaa atttatatga acgtgctgaa aatatgcctg gtaaagcagg tgagaactta
    14461 ttaagtttat tagagagaag attagataat gtagtttaca gaatgggact agcatcttct
    14521 agaaaagaag ctagacaatt agtgactcat ggtcatttca ctttaaatgg aaataaagta
    14581 gacatacctt cattaatagt taaggttgga gatgttatag aagttaaaga gaaatcaaga
    14641 tcttctgcaa aattcaaaaa tttagtagaa gttaactcaa gaatagctcc taagtggtta
    14701 gaagctaatg tagaaggaat gacagcaaaa gtagttggtg ttccaacaag agaagatata
    14761 gatcttgaga tagcagagca cttaatcata gaactttact ctaaataata agcacacttt
    14821 taaaaattat tttaaaattt tgtttaccct cagtggatta ctgaatttta aggagggttt
    14881 tgtccatgat agaaatagaa aagccaaaag tagatatagt tgagcttagc gaagactata
    14941 gatatggtaa gtttgttata gagcctctag aaagaggata tggaataact ataggtaacg
    15001 cattaagaag aatattatta tcatcattac caggtgtagc agtgaatgct ataaaaatag
    15061 atggagttct tcatgaattt tcaacaatac ctggtgttaa agaagatgtt actgagataa
    15121 tattaacttt aaaagagctt tcagcaacta tagatggtga aggaagtaga acacttaaaa
    15181 tagaagctca aggaccatgc tctatcacag gtgcagatat aatctgtcct ccagatgttg
    15241 aaatattaag taaagattta gcaatagcta cattagatga taatgctaaa cttaatatgg
    15301 agatatttgt agataaaggt agaggttatg tttctgctga agaaaataaa acagagaatg
    15361 ttccaatagg tgttttacct gtagattcaa tatatactcc tgttgagaag gttagttatc
    15421 atgtggaaaa cacaagagtt ggtcaaaaaa cagattatga taaattagta ctagaagttt
    15481 ggactaatgg tagtataaat cctcaagagg gaatatcatt agctgcaaag gtattagttg
    15541 agcatttaaa cttatttata gacttaactg aacatgtaag tagtgttgaa atcatggtag
    15601 aaaaagaaga agatcaaaaa gaaaaagttc ttgaaatgac tatagaagaa ttagatttat
    15661 cagttagatc atataactgt ttaaagagag cgggaattaa tacagttgaa gaattagcta
    15721 ataaatctga ggatgatatg atgaaggtta gaaacctagg taagaagtca ttagaagagg
    15781 taatacaaaa actagaagaa cttggattgg gattaaaacc aagtgaagaa tagcgagcaa
    15841 aggagggata agaatggcta agtaccgtaa attaggacgt gaaacagctc acagaaacct
    15901 tatgttaaga aacttagtaa cttgcttact aagaagtgga agaatagaaa ctacagtgac
    15961 tagagcgaaa gaaactcgta gaatggctga aaagatgata actcttgcta agagaggaga
    16021 tcttcatgct agaagacaag ttttagctta tgttatggat gaaacagtag ttaataactt
    16081 attcacagat ttagctccaa aatatgctga gagaaatggt ggatacacta gaataataaa
    16141 aatagggcca agaaaaggcg atgctgctga aatggctttt atagaattag tatagtaagg
    16201 aaaggattag gcttgatggc ttaatctttt ttttattttt ttgactaagg tatgatataa
    16261 taatgtgtaa aatgattttt ataagttatt gcttactaaa aggagtatga gttaatggat
    16321 aatatagtaa aggtaaataa tatttcgttt gagtatatta cagatgaagc aaaacttaaa
    16381 gcaatagata atttaagcct agatgttaaa aaaggagaat ttgttgcgat aataggacat
    16441 aatggttctg gtaagtctac tttatctaaa aacttaaatg ctattcttat gcctactgaa
    16501 ggaaatattc ttattgatga tatggatact aaagaagaag aaagattatg ggatataaga
    16561 caaactgcag gcatggtatt tcaaaatcca gataatcaaa tagttgctac tatagtagaa
    16621 gaagacgttg catttggacc tgagaactta ggtatagaac caaaagaaat aagacgaatt
    16681 gtagaggagt ctttaaaaag tgtaggtatg tatgatttaa gagatagaca gcctcatttg
    16741 ttatcaggag gtcaaaagca aagagttgca atagcaggaa ttattgctat gaggcctaaa
    16801 tgtataatat ttgatgaagc aacagcaatg ttagatccat ctggaagaaa agaagttatg
    16861 aaaacaataa aaagacttaa taaggaagaa aatataactg ttatacatat aacgcacttt
    16921 atggaagaag cagtagaagc tgatagagtt gtagttatgg aaaaaggaaa gaaaatctta
    16981 gagggaactc ctagagaagt attcagtaaa ataaagatgt taaaggaaat cggtttagat
    17041 gtaccttgta tgacagagtt atctagttta ttaatagaag aaggtataaa tattagtagt
    17101 gatatattaa ctgtggatga gatggtgatg gaattatgtc aattatagta aagaatttaa
    17161 cacatatata taatgaaggg atgccttttg caagtaaggc acttgatgat gtttcttttg
    17221 agattaaaga tagagatttt gttggtctta taggtcatac aggctcagga aaatctacat
    17281 taatacaaca tttaaatgga ttactaaagc cttcctcagg agaaatattt ataaatgatt
    17341 ttaatataac agataaaaac ttgaatttaa ctgagattag aaaaagagta ggggttgtat
    17401 ttcaatatcc agaataccaa ttgtttgaag aaacgattga taaagatata gcttttggac
    17461 cctctaattt aggcttagag gagtctgaga tacataacag ggtaaaagca tcaatggaag
    17521 ctgtaggact tgattatgag ggatttaaag acaaatctcc ttttgaatta tctgggggac
    17581 aaaagcgtag agtagcaatt gctggagtta tagccatgaa cccagaagtt ctcatattgg
    17641 atgaaccaac tgctggtctt gaccctggtg gaagagatga aatttttaac ttaataaaag
    17701 acttacatga aaaaaagaat atgactataa tactatcatc acatagtatg gatgatatgg
    17761 caaagttagc aaaaacttta attgttatga atcatggtag cgtagaattt atgggaactc
    17821 ctagagaagt atttaaatca aatgctagta aattaaaaga tataggatta gatattccac
    17881 aagttttaga gcttgcattg aaattgagag aaaaaggctt tgacatcagt gaggatatat
    17941 tgactttaga agaagcaaaa caggaaatat taaaagttgt gagaggacga ggattatgtt
    18001 aaaagatata actatagggc aatactaccc aacaagttct gctattcata aattagatcc
    18061 aaggataaag cttgtagcga caattgtatt tatggtatct atatttgtag taaataaatt
    18121 ttggccttat atagtagttt tattatgttt attagctatg ataaaattgg ctaatatacc
    18181 agtcaaatat attgttaagg gtgttaaacc tcttaaatgg attattttgt ttacatttct
    18241 tataaatatt tttttcttac caggtgatga aatatggtca tttggatttt tagctattac
    18301 aaaacagggt ctaagacaag caatttttat ggcaataaga ttaatatttt tagtagttgg
    18361 tacatcattg cttactttaa caacttcacc aatagaatta actgatggaa tagagagatt
    18421 gttgaatcca tttaagaaaa ttggtttgcc agttcatgaa cttgcaatga tgatgacaat
    18481 tgctttacgt tttattccta cattgttaga tgagacagac aaaataatga aggctcagat
    18541 gtctagaggt gcagattttg aaagtaagaa tcttataaat agagcaaaga atttagtacc
    18601 acttttggta cctttatttg taagtgcatt tagaagagct gatgaattgg ctatggccat
    18661 ggaggccaga tgttacagag gtggacataa taggactaag atgagagagt ctgttatatc
    18721 aagaagggat tatatggcat gtgtatttca ggttgtttat ctgggagcaa ttatagctac
    18781 tagatttata gcaatttaat taataagtta tagatataat gaggtaaagt atgagaaata
    18841 taaaaattaa aatccaatac aatggtaaga attattgtgg atggcaaaag caacctgatt
    18901 ctttagggat acaaggtaca attgaaaggg ctatatatga tataacaaaa gaagaaacca
    18961 gtcttatagg gtctggtaga actgattcag gagttcatgc tattggtcag attgcaaatt
    19021 ttaaaattaa ttcaggtata agtatagaaa gtataccaat ggcactaaat gccaagttgc
    19081 caaaagacat atcagttata gaagcatgtg aagtaaatga tgattttcac tccagataca
    19141 gtgcaaaagg taaaacatat aaatatttag tatataatag caagtttaga aatccaatac
    19201 ttagtgagat atcatatcaa gtaaaatatg aacttgattt tgataaaatg tgttcagaag
    19261 caaaaagttt attaggaaca catgatttta aaggttttat gagttctggt tcatctgtaa
    19321 aagatacagt tagaacgata tatgatattg atataagtaa aaaagatgac ttgattactt
    19381 ttgagattag tggtaatggt tttttatata acatggtgag gattattgtt ggaacacttg
    19441 ttgatatggg tcgtggcaga attaacgaac catttttaga tataatacaa tcaaaaacta
    19501 ggtcaagatg tggacataca gctccagcac aaggattatt tctcaaaaaa gttcattatt
    19561 aacttgacac accaggctac atgtattaaa atatatgaga atgtgttaat aagtccactt
    19621 gccccggact tgacataaac ggtaaaaaaa ttttatgaaa agtagttaag gagggacagt
    19681 tatgaaaagt tatatagcta agccagctga tgtacaaaga aaatggtact tagttgatgc
    19741 tgaaggaaaa acattaggtc gtttagcaac agaaattgcg acagtattga gaggtaaaca
    19801 taaaccaaca tttactcctc acgttgatgg tggagatttt gttgttgtag taaatgcaga
    19861 aaaaatagtt ttaagtggta agaaattaga tcaaaaatat tacagatacc atactggtta
    19921 tgtaggtgga ttaaaagaaa tatcttatag agatatgatg gataagaaac cagaagaagt
    19981 tatatcacat gctgtaagcg gtatgttacc taaaaataaa ttaagaagca gaatgatgac
    20041 tagattaaga gtatttgcag gtgctgagca cactcatgca gctcaaaatc cagaagtttt
    20101 aaactttaaa taagattaat aggtgaaagg aggagtttat aatggctaac gttcaatatt
    20161 atggaactgg aagaagaaaa agttctgttg ctagagtaag actagttgca ggtgaaggaa
    20221 atatattagt aaatggaaga gcattagaaa attattttaa ttatgagaca ttaataagag
    20281 atgttaaaca accattagtt ttaactggta atgaaaataa atatgatgtt atagtaaaag
    20341 ttgaaggtgg aggattcact ggacaagctg gagctataag acatggaata tctagagctt
    20401 tattaaaagc tgatttagat ttaagacctg ctttaaagaa agaaggtttc ttaactagag
    20461 atgcaagaat gaaggaaaga aagaaatacg gattaaaagc agcaagaaga gctccacaat
    20521 tctcaaaaag ataattactt atttttttgg aaaagcaaaa tcttttattt actgttattc
    20581 agaaagtatt ggtattttaa aaatgttggg ttaagttaat tattgatata taataaaata
    20641 ataagatatc ttattaggat gtttttcatt aagaagaaca tcctttttat tttgactatt
    20701 taataaaaaa catatgctaa taacatttaa attttatttt tataatattg taatttaaaa
    20761 gtttatataa ggttatatat tttaagatat tatttaacaa tataaattct gaatatacgt
    20821 tatcaaagtt tataatataa actaagtata atttattgta tagtattgaa tgttagataa
    20881 acatagtgaa ttaaataggg gcagaaatat aatatcatta cataataata tattaatacc
    20941 aataaataaa gatatatcaa tattaaaaaa atttaaatgt ttgtactaat atatggaata
    21001 ttatggtgtt tttataagta tacatataca gggtgatgtt gtgagaaagt acataaaaca
    21061 tataattttt agttttgcaa tgatatgtct agtagtagta tccatatttg aaattaaaaa
    21121 tatttctgaa gatgttatca agtatatgcc agtaacaaac aaaactataa ttttagatgc
    21181 tggtcatgga ggcattgatc caggtgcatt aaataaggat aagagtacat ctgaaaagga
    21241 tattaaccta gcaataacac ttaagcttag agagcttata gaatcaagtg gtggccttgt
    21301 aatattaact cgagaagatg acagtagcct ttataaagaa gaaaataata aaactacaag
    21361 acaaaaatat aatgagaatt tgaaaaatag aaaagaaata atatctaatt ctaatgccaa
    21421 tatgtttgtc tctatacatc ttaatgcatt tgaacaatca aaatactatg gagctcaaac
    21481 tttttatcct aaagacaaac aagacagtaa agcattatcg aagtgtattc aagaagaact
    21541 taaaagagta gtagataaga caaacaacag agaagtcaaa ccaagggatg atatatatct
    21601 tttgaaagaa aataatattc catcagtact gatagaatgt ggttttttat caaatgaaaa
    21661 agagtgtaaa ctcttaactg atgaaacata tcaagaaaaa atagcatggg caatctacat
    21721 aggaatacaa aaatatttaa gttgaaataa ctataaaaat aggtctaaat atgtaaatag
    21781 cttgtattaa agcagttaaa atgcattaat ataggctatt tttattttga caaaaaaata
    21841 tttaaaataa aagttaaaaa gttgttgact tagaataata tagatgatat tatatatgag
    21901 tgcccaaaag gagcaccaaa ataagacaaa agaactttga aaattaaaca gtaggttaat
    21961 tta
//
LOCUS       DAEOTL010000070        21880 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEOTL010000070 DAEOTL010000000
VERSION     DAEOTL010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21880
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.070"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            133..369
                     /locus_tag="KRH82_002903"
     CDS             133..369
                     /locus_tag="KRH82_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656171.1"
                     /translation="MNNMENKKNFLRKIVKLRSIFLSIFGVFLFITATTGIQTVDRYV
                     PTWLYITLGVSATISLVLYVISFILKINIKDSKM"
     gene            complement(1131..1361)
                     /locus_tag="KRH82_002904"
     CDS             complement(1131..1361)
                     /locus_tag="KRH82_002904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656172.1"
                     /translation="MKKYTKDLHIMSERNSYSKTDNDATFMRMKEDHMKNGQLKPAYN
                     IQFGVDSEYIVLVSSGHQPTDTITLIPFLKSI"
     gene            complement(2026..3345)
                     /locus_tag="KRH82_002905"
     CDS             complement(2026..3345)
                     /locus_tag="KRH82_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8656173.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(3386..4132)
                     /locus_tag="KRH82_002906"
     CDS             complement(3386..4132)
                     /locus_tag="KRH82_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBG8656174.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(4376..6385)
                     /locus_tag="KRH82_002907"
     CDS             complement(4376..6385)
                     /locus_tag="KRH82_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656175.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGEASLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEAMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(6823..8256)
                     /locus_tag="KRH82_002908"
     CDS             complement(6823..8256)
                     /locus_tag="KRH82_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBG8656176.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDILQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(8272..9696)
                     /gene="ascB"
                     /locus_tag="KRH82_002909"
     CDS             complement(8272..9696)
                     /gene="ascB"
                     /locus_tag="KRH82_002909"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBG8656177.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFVEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYNRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(9783..11699)
                     /locus_tag="KRH82_002910"
     CDS             complement(9783..11699)
                     /locus_tag="KRH82_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8656178.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(11773..12633)
                     /locus_tag="KRH82_002911"
     CDS             complement(11773..12633)
                     /locus_tag="KRH82_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8656179.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(12984..14171)
                     /locus_tag="KRH82_002912"
     CDS             complement(12984..14171)
                     /locus_tag="KRH82_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656180.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(14185..15576)
                     /locus_tag="KRH82_002913"
     CDS             complement(14185..15576)
                     /locus_tag="KRH82_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBG8656181.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(16171..17871)
                     /locus_tag="KRH82_002914"
     CDS             complement(16171..17871)
                     /locus_tag="KRH82_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8656182.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYLIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(17843..19246)
                     /locus_tag="KRH82_002915"
     CDS             complement(17843..19246)
                     /locus_tag="KRH82_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656183.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELEEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(19510..20001)
                     /locus_tag="KRH82_002916"
     CDS             complement(19510..20001)
                     /locus_tag="KRH82_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8656184.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(20027..20839)
                     /locus_tag="KRH82_002917"
     CDS             complement(20027..20839)
                     /locus_tag="KRH82_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8656185.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(20852..21811)
                     /locus_tag="KRH82_002918"
                     /pseudo
     CDS             complement(20852..21811)
                     /locus_tag="KRH82_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         6935 a         4087 c         2265 g         8593 t
ORIGIN      
        1 aagataaaaa aataaaacaa aacagtagct aggctttaaa taaaatatta aatactataa
       61 tttatagatt aaatctgata ttattatata catctggaag ttgttgctat tatttaaaaa
      121 ggtgggatgg atatgaataa catggaaaat aagaaaaatt ttttaagaaa aatagtaaaa
      181 ttaagaagca tatttctaag catatttggt gtgtttttat ttattacagc aactacaggt
      241 attcaaactg ttgatagata tgttccaaca tggttatata taacattggg agtgtcagca
      301 actatatcat tagttttata cgttatttcc tttattttaa aaataaatat aaaagatagt
      361 aaaatgtagt acttcataaa cttccagtaa aagaataatt ttgataaatc aaaattattc
      421 ttttttaata tcaaaataaa taataaaata acaaaataaa tagaaaatat aactaaaaaa
      481 ttatcaaagt ttaagatgat aattttatat ttgataaact tatgtaatac attgtaaatt
      541 aacttctcaa aatttataat tcttagcata aaattataat ttaatattaa aattttacaa
      601 aaaagtaatt tattaaatga ctaggataat caataaaact ttataatttc cacaaaagtt
      661 atgatgaaat tgttgattta gatataaatt tatcagtaaa acaaattagt aagttaaaaa
      721 acgatcttat aaaaagatta aaataaatcc ttttattgga attttaagag attttgtttt
      781 tattataaat aaaaaattta ttggtttatt atttaaaaac gttacaagtc ttttaaagct
      841 ctttaaaaca gccttttaaa ttactttact taaatatttt tttgtttaac ttatttttat
      901 aagtaataaa catataaaca tcacttatgt aaattaatga tttttaaaat aaagatattt
      961 ttatttttta tataaacagt acagaataaa aaaatatttg tgttttccct tttactattc
     1021 tattttaaaa atattttatt tattttatat ttctctaaaa atgtatagtt ttcatcactt
     1081 tcatacccag aatcatccac tattttagga tatttaaact ttgtatggaa ctaaatagat
     1141 tttaaaaatg gtattaatgt tatagtatca gtgggttgat gtcctgaact taccaaaact
     1201 atatattctg aatctacacc aaattgtata ttatatgctg gtttcaattg cccatttttc
     1261 atatgatctt ctttcattct cataaaagtt gcgtcattat ctgttttaga ataactattt
     1321 cgttcactca ttatatgaag gtctttagta tattttttca atctatcaat acaatcattt
     1381 aattgctcta tagatttgtt ctttcccttt ccatgaacaa atgttatatt tgattctttt
     1441 gatatttttt aaccttcttt aaaaatttcc ttaaatgatg gattttaatt ttatctttat
     1501 aaattatttt aataccaaaa tcaatctcac attttaatat gaagtcagat atattattca
     1561 tcattttagc catattttta tttatagctt ttttcaaaca aaagtatatc tattagcaga
     1621 tgactctatt tctcttgaag aataaataca gttaatgttt gtatatatta taattttcaa
     1681 aagttgtcta ggggttactc tatttcctct aattcgagca taagtcttat ataatttttc
     1741 taaattcatc tactcaataa tttgacttaa taaccttaca gaatcatctt ttggaatcat
     1801 gtaatcaata cttagtggta atttaaattg ataattatcg ccataagtag tataattaaa
     1861 ctatatacca ttttgtttta acacacaatt attatacaag actcccaaac tcttttgaac
     1921 ttgggattct tgtataataa agggtgtagc actattttct agtgatacag ccccatttcc
     1981 ctaaattcaa agtaatattt atagaatctc tatagattac aataattatt tgacttctac
     2041 atcattatat ttctttgaat atactttagt catatagaaa tatataggaa ctacaattat
     2101 catcccacct aatccccaaa ctatcttcat aggttcatca atacctgctt ttatcagtaa
     2161 taatatactt ataataactg caaatattgg tataattgct cctccaggta ttctaaaatt
     2221 tacatcttta ccagcatact tctttctcaa tattagtaca gctagacatg taggaatata
     2281 ttgaataaat ctagatacaa cacttatttg agataatgtt gtgaatgaac ccgaccatgc
     2341 tattagtaaa gttcctatga cagatactat aattgctata taaggagctc catttttatt
     2401 agtttttctt atagacttag gcattaatcc ttgttcaacc aaagcagcag cagaccttgg
     2461 tgtaaatatg gatgatgcaa tatttatacc tccaacagat actatagttc ctattgtaat
     2521 tatatacccg cctataggac ctaacatctt aatggcagca tctgcaacag gagtagctga
     2581 ccctgctaag ccattaccca acacccctat acttattccc agtataagca tatatattac
     2641 tgatactaca aacattacca ttaccaatgc tttaggtaca tttttcttag ggttctccat
     2701 atcttttgct gcaacagcta aagattcaaa tcctgtaaaa gcataaaata aagttataga
     2761 tactgctaca aaagctgatg acgcactttg acctttttgt attattacaa atggggtaaa
     2821 attagaaccc tttataaaga ataatcctac agctataaat aaaactattg gtaataattt
     2881 tcctatagtc atgatattat ttaagtgctt agattgtttc attcccataa aatttataat
     2941 cccaagccct acaactaata taccaattat tatattttta gtaagtggtt ctgctgcttg
     3001 tggccataca gatgatagtg ttacagcaaa gaaatttgcc atagtagccc aagcaatcat
     3061 actaactatc cacttcataa atccaacttc aaatccaaca aaatctccaa atgcctcttt
     3121 tgcataaaga tagggccctc catcagtatc aaaccaacta cctgcttcag caaaacataa
     3181 agcaatagaa acagctaaaa gcatacaaaa aactaatact aatatacttg ctggacctat
     3241 atctgtataa gcatcaccag gtaacccgaa tatacctgac cctattattg cattgattcc
     3301 taatagtaca atactccaaa aacctaactt aatgcctttt tccattgtta ttccccccaa
     3361 agccaactta atatatttat attttttatt tagatgcttc tttaactatt gccataaata
     3421 tttttttcat attatcataa tccctagtca tcatttctgg atgccattgt atccctatta
     3481 caaactcact tccttccttt tctatagctt caattaaacc gtctttagat gtagctgaaa
     3541 caatatatcc cggtgctact ttgttgacaa ctaagtgatg aaaactatta actaaaactt
     3601 ctttttctcc taatatttca tataattttg tcccctcctt tatctgtact gtatgtgtag
     3661 gtacattaga tagatgttgc tgattgtgtt taatataagc accttcaatt aaagataaat
     3721 cttgatacaa actacctcct tcagttacat ttataatttg ttctcctcta catataccta
     3781 aaactggttt tttcatatct aaagcatgtt ttaataattt catatcaaaa ctatctctct
     3841 ttggtgatat tgcccccaac ttattatgag gttcttcttt ccatatgagt ggatttacat
     3901 cttgtccccc agatagtata agcgcatcta tattagatac ctgttccttt ataatctcat
     3961 catcatatac aatcggtaca atatatggta tagctttaca cataactact gattgtatat
     4021 aatcattatt tacataagcc ctttcatagc caggaaacat tcctccttca tcaattagta
     4081 aattacctga tattcctatt attggatatt tctttttagc caatttcttc accccttaac
     4141 ttatttgtga acaataaaaa atgctacttc tcttaaagag caagtagcat accaagattt
     4201 tatttatttg aacattataa tttattttag aaatactttt tttgaatacg agtaatataa
     4261 ataactttat ttacttatat tttattttaa tcctgtttag tttgactttt ttaaattgtt
     4321 ttaagtacaa ctaataggta aaataggcat ttagattttc ctttttatca acctattaaa
     4381 tactgtttaa tatatttttt ccccttctat ttaattcact tccctttcta ccagattcac
     4441 atattatcaa atccagctct tttaacatat taagtattcc ccttacctca ccttctgtta
     4501 tattgtagcc taattcattt attgaattaa caataccatt tctacctata tttttattaa
     4561 gattattggc attttttaaa cactccatta ctaactttac tttctctata gatgttctat
     4621 cctttaatat acttatttct ttactaaaat cttcagttat atttaataag ttatgaggta
     4681 aatcatttat taaaataaca tcctcagaac tcataatgtt aatatacata gcagtatttt
     4741 ttaattctct tatattacct ggccattcat atgcattaat aatgtcttga acatcttgac
     4801 taattgctct cttccttttc ataaaatgct ttaacatagc ttctatatct tcttttcgct
     4861 ctcttaaagg tggtatattt atgggcaata catttatcct atagtataaa tctgctctaa
     4921 atctatctcc ttttatcatt tctaataaat ttttatttgt agccgcaatt actctaacat
     4981 ctatatctat tacattttct cctccaaccc tcattacttg attctcttgt aatactctaa
     5041 gtaatttgct ttgtaagtat ataggcatgt ctcctatttc atccaaaaat atagttccat
     5101 tgttagcctg ttcaaataat ccttttttac ctccttttaa agctcctgta aaagcacctt
     5161 cttcatatcc aaaaagttca ctttcaagta aattttctgg catagctgca cagtttatcg
     5221 caataaatgg ctgactatgt cttggtgatg cattatgaat agactgagcc atgagttctt
     5281 ttcccgttcc actttctccc gttataagaa ttgtataatc agattcagct attttcatac
     5341 ctaatttctt agttctttcc atcttcgttg aaactgtttt tatatcatca aaagtatatc
     5401 tagcaacttg tcccttttct ctaagcttct ttgataggtt ttgctccaat tttcttatgt
     5461 aagttatttc ttgaatacaa aaataatatc cagtaaccct tccaaaactc tctatattat
     5521 acttatttac gtttaagtac ttattattaa attttataac ttcatcatgt gccttactca
     5581 aactaaaaat ctttttaata ttctcattct ctaattcatc tatatttttc cctataatat
     5641 tactttgaat atctagtata tcccctaaac tattattgca aataattatg tttcccttat
     5701 ctgataccat tgccatacct aagtttgata aatttattat ggaatttagt tcatctgctt
     5761 ttatagtaag ttctttgtat ttagtattta ttcctgaata taaactaatt atttcatctg
     5821 tatacttaat tagcctttca gtaatttctt tatcatccag tttgagtttt gctattattt
     5881 gaataaacgt tgaactatca atatacctat ggcctaaatc aataacttct tctatatatt
     5941 ttggaactaa acttgcctct cctggcgtta tagctatctt aatatttcta tattcttcat
     6001 tgggattgta tggtataaaa ttcagatgat ttattcctat attgtataaa ttagatattg
     6061 tttccaatac agtatgctta ttatcgttta ctactaatac atctattcct tctggcaatg
     6121 aaaataactt atatatatcc ttttgcttta tactcctatt tatagttatt atctttgaga
     6181 catcttctac atattttttt atttttaata ctctatcatc tatcattacc aatattatgt
     6241 catcttttat taattccttc tctgttattt tatttaaata ataatttttt atcattactt
     6301 tatctttaaa tatcatttct agatttttat ttaagaaaca ttctaattta gacaacccat
     6361 cagttactac tgctattgtt ttcatttgat tactcctttt aaaatatact ctactctttt
     6421 ataatataca tctgattttc actttaacag cacaaaaaat tgtacattta gtatactaac
     6481 atattccttt attagtttta tgtccctaaa tatcatagtt gcaatatcta tcatatttcc
     6541 taaacttcta tagagcaaaa attgtgccaa attaataatt ttcttaattt tattctaaag
     6601 ttcctcaata gtatttacag acttagcact tatagcttat aagtctttat attattaatc
     6661 tatttttata ggttaattgt acaaatcata tatcactttt acccattaaa tgcattataa
     6721 aaaagatgga ataacgattc gttactccac cttttttgta ataaaaaatt gtatatataa
     6781 acactattta ctactcttct aagtacaaac agtatctaca tactataacc tttcaccatt
     6841 agattctatt acttgtttat accagtcaaa actctttttc ttaatcctag acaagtctcc
     6901 acttccatca tcatacttat ccacgtatat aaacccatat ctcttggcca tctcaccagt
     6961 agatgcactt actaaatcta tacatcccca tggagtatat ccaaataaat caacaccatc
     7021 ttctacagct tccttcattt gctctatatg tgcttttaaa tactctatac gatagtcatc
     7081 atttatcact ccattagatt cttttttatc ataagctcct aaaccatttt caactaccat
     7141 cataggtatt ctatatctat cataaatttc atttagtgca tatctaagcc cttcagggtc
     7201 tatttgccat ccccattcac tagacttaag atatggattt ttcactccac ctaatatgtt
     7261 gccacttgta ttatcttctt tagaatcact acttacacat gtagacatat aataactaaa
     7321 tgtataaaaa tctacacaac cttcttttaa aatttctaaa tctccttttt ccatttttat
     7381 ttcaatatta ttttctccaa aatatctatt catataagtt ggatattcgc cacgcacttg
     7441 tacatctcca cagaaataat tcattactct actatctctt tgagttttaa ctgcatcatc
     7501 tggattacaa gtataaggat acattgttgc aaatatttgc atacatccaa cttgataatt
     7561 tgaatctatt tcatgagcta acttaacagc cttagcactt gctacaaatt gatgatgtaa
     7621 cccttgaaaa cgaagttgaa gtatatctac ttggtttata aaatctgtag tcccttcatt
     7681 taatattcct tgtgataagt agcctcccat aggcattgta gctgaattta tttcattaaa
     7741 tgtcagccaa tattttactt ttcctttata tcttttaaat attgtttcac agtaattcat
     7801 atacaagtct attacatctc ttgaaaccca tccattgtat ttctctgtta ttgcaaatgg
     7861 tatttcatag tgagatattg ttattaatgg ttctatatta tattttaaac attcatctat
     7921 cacattttca taaaatttaa gtcctgcttc atttggttct ttctccattc cagttggaaa
     7981 tattctagtc catgctattg aaaatctaaa taccttaaat cccatttctg caaataaagc
     8041 tatatcttct ttgtatctgt gataaaaatc tattgcttca tgacttggat aaaatgttcc
     8101 tttttctata actctcgtta ttcttttact tactttttga gaacctccag tacacatatc
     8161 tgaacaagaa ggacctttcc catctaaatt ccatgctcct tcacattgat ttgctgctgt
     8221 tgctccaccc cataaaaaat cttttttaaa tgacatacct atatcctcct attataattc
     8281 ttcaccattt gattctatta cttttttata ccaggcaaaa ctcttctttt tactgcgttt
     8341 taaagttcca tttccatcat tatctttatc cacatatata aatccatagc gcttcttcat
     8401 ttctccagta cttgcactta ctaagtcaat acatccccat ggtgtgtacc cccataaatc
     8461 aacaccatct aactcaacag catctatcat ggcttttata tgagcacgta aataatcaat
     8521 tctataatca tcatttatat ttccattttc atctggatta tctactgctc ctagtccatt
     8581 ttcaactata aataatggtt tttgataacg gttatataaa gagttcatag ttattctaag
     8641 ccctaatggg tctatttgcc atccccactc acttgcatct agatatggat ttttaagact
     8701 tgcaaaaaca tttccttctg ttaaaatatt tacttttggg tctgcacttg taagtcttga
     8761 tgagtaatat gagaacgaaa taaaatctac tgtgttctct ttaagtatct ttttatcatc
     8821 ttcttccatc actatattta ttccttttct ctccaattct tttaatgcat atgttggata
     8881 ttctccacga gattgtacat ctataaaaaa gtaattttcc ctatcttttt ctatagattt
     8941 ccatacatct agtgggttac aagtattagg ataagtattt cctgctgcta acatacaccc
     9001 tattttaaat tcttgattta tgttatgtgc tagtttagta actaacgcac tcgcaactaa
     9061 ttgatgatgt gcagcttggt attttatttg ttcttcattt tctccctctt caatatagag
     9121 acctgcacct ataaatggta aatgaagtat catgtttatt tcattaaatg ttagccaata
     9181 ctttacctta cctttaaacc ttgtaaaaat aacttcacag tattttacat ataagtctac
     9241 tagcttacga tttctccatg ctccatattt ttttaccaaa tacatgggaa catcaaaatg
     9301 acagattgtt actactggtt ctattccata ctttaaacac tcatcaaata aatcttcata
     9361 gaattttagt ccctcttcat ttggaacatc ctcaactcct gttggaaata tcctagtcca
     9421 tgctattgac atacgatagc atttaaatcc catctcaaca aataatttta tatcttcttt
     9481 ataattgtga tacatatcta ttgcttcatg agctgggtaa tagtgttcat catcacattc
     9541 aaacattttc attttcccag ccaaaactgg aaatctatct tttccttgcg gtgtaacgtc
     9601 aacattagct agacctctac catcttcttt atatccacct tcacattgat ttgctgctgt
     9661 tgctccaccc cataaaaaat cttttctaag tgccataatt ctacctccaa taatttattt
     9721 atagtaactt tattttaaaa taaaaataca tatatataat tcttaattaa tagaactctc
     9781 ttttacgcta aaacagttat caatttctga ctattattta catgcttttg tgtattttct
     9841 acaatatcca cataatcaga ataattagta acaactactg gtgtttctaa gcaatatcct
     9901 tcttttgaaa tactttctat gtcaaaagtt attaatgtct gacctttttt aatcttatcc
     9961 ccttgattaa caaaagattt gaaatattta ccttccaact gaatagtatt taaccctata
    10021 tgtatcaata gttcacaacc attatcagat ataattccta ttgcatgttt tgttggaaat
    10081 aaagtcatta cagtcccatc aaatggtgcc actacttttc cttctttagg tgttattgct
    10141 acaccttttc ccaatatacc tgttgaaaac gctgcatctt gtatctgctc caaagccttt
    10201 acttcacctt ttattgggct atatactact tctcttttgt ttttttctat aacgccttgc
    10261 ccattatcat ctttagaaat ttctactata gcatcatctt tccaaaaaaa taatgttaaa
    10321 acaaatccta ctacaatagc tactattatt gctattatag ttgcataaac acctttcata
    10381 tctccagttg ttggatttat ataattaggt ataccaaata ttccaagtcc acccattaca
    10441 taacttttta cattcattat ccccattaca gctcctgcca caccaccacc tacacagcta
    10501 tatatgaatg gtgtttttct tggtaaagtt attccatata ttgcaggctc tgttacacca
    10561 catatccctg aaataactgc aggtatacac agctctttta tcttcttatc ttttaattta
    10621 aagtacattg ctgctactac tgctgtttgt gcaaaagatg gtacaaatgc tcccactaat
    10681 attgtgtcaa accccatagt cataaggttt gacatagcta ttggtactaa tccccaatgt
    10741 agaccaaata ttacaagcac ttgccacaat aaaccagtta atgcaccaca taaaattggt
    10801 gaaaagttaa ataaagctaa aaatccattt ccaactatat tagaagcata ggtagctata
    10861 ggccctataa ccataaatcc caatggtaaa gaaactaata aaactgccat tggtacaaag
    10921 aaattcttta ctacatctgg tattatttta gcaaacactt tctccaactt agctgctaat
    10981 aatactatta aaattactgg tactactgtt gaagtgtagt tcattgctat tactggtaat
    11041 cctaagaaag ttatatatac tggtgattca aatattgttc cagtaaatag attgtataaa
    11101 ggttgacctg tagatgctag agtatctaat tgaatacctg aatagcataa aactgcacct
    11161 ataagcattc caataaatgg ttttaatttg aatttcttag cagctgtata tccaagaatt
    11221 attggcatat actggaacat tgcatctcca attgcattta acataatata tgcaccatca
    11281 gtttctccat acaaacccaa tgctgtaaat actgcattaa atccttttat cataccagca
    11341 gcacacagaa ctcctaatat tggttgaaaa actcctgata ttatgtctat aaacttatta
    11401 agtaatcctt ttggcgcatc tgaatctgaa ttatctattg tatctcctcc taatccagcc
    11461 aaatcgcaca caacttcata aacatctgga acatgattac caataactac ttggtattga
    11521 cctgcacttt tcattacagt aactatacca tccatttttt ttagcacatc atcatttgct
    11581 attgactcat cttttaattt aaaacgtagc ctcgttatac agtgagataa actgctaata
    11641 ttatcctttc ctcctacatt cgcaatgatt tcttttgata gttgttcata ctttctcatt
    11701 ttttctcctc cattttcttt ttgaaatatg aaggtttggc caacttaatg tcaccaccca
    11761 atatatataa acctaattat taggatttat atctgactta atacttttac ttaccactct
    11821 ttcaacgtga atagttaagt ataatttttc ctcatctgtt aaatcgtagt tgtatttttt
    11881 atgtataaat tcatccaact tttctatgaa tttataagca tttttatatt taacttttat
    11941 tacatttaat aaatcatctt cattattttc atgtaaatta ttactaacaa ttcgttctgc
    12001 aaaatacttt aagtgagtaa taaatctatg ataataaact gaatcttcat caaatactat
    12061 tctgtaatgg tatttaacca tatttgaaat ttcttgtatt atttgtgtaa tctcatatat
    12121 agtttttata ctttgatcca tttgtgcatt aactatatgc agtgctataa atccagcttc
    12181 atcttctgat agtctaattt caaatttttt ttctatataa tccaatgcct ctaaccctat
    12241 tttaaattca ctcttataaa atctttttat atcccaaagt aatacatttt ttacacttac
    12301 tccttcacga gctctttcta ttgcagtata catatggtct gttaaagaaa tataaatact
    12361 atcatttaat cttttcccta gtttttcttt agcatataaa attatttcat ctgataattc
    12421 catatatctt ataggaatat ctgctattag ttctttaaat ttatcagata tatttgggtc
    12481 tgaaagtttg aatatcttat caattttatc ctttgatata tgctctcctg tacgtttttt
    12541 ataagctaaa cctctcccca taactactat ttccttatga ttttcatcag ttgtaataat
    12601 tacattatta ttgagtattt tttcaataat cattgtgatg ccccctttat tagcattaag
    12661 ttaaaataaa tcttttttaa ttatttagaa tatttaaaat gtaatttatt acataaaaaa
    12721 aaacctattt attacacatt aaatagactc ccatgagtcc tgagtaataa ataggtttag
    12781 cttgtattta aacaatcact atccgtttgt attttatttt aattattatt tattatatgt
    12841 tagcaaattt attttttagt gtcaactttt tctcaatatt ttaattttaa ataaattata
    12901 taaattgaat cttcaaagta ctatttttat caataaacaa aataaaaaag gtattacttt
    12961 ctttaagtaa tacccattta tttttaattt aagtggtttt tcttaatctc atcaagtagt
    13021 ccatcttcta aataaatttc taatgcacat cctaccattg cctttactgc tttgtgaagt
    13081 ttatcataag cttcctcaga atttgcataa tttagaaatt ctttttcatg aacatatacc
    13141 attggactta tatctaaggc tatttctgta tacatagtag ggcaaacttg acttacatta
    13201 cctatatctg tagaacctac tggaccatct ttaccttcta atatatctgt tatacctgcc
    13261 tcaatcaaat tattctttgt tatcttttga agtactttgt tatttattat gttgtcaaaa
    13321 gaattttcaa agtatctata agaaagctta gctcctgtca ttaactctgc accttttgca
    13381 cagtttataa cttttttagt tacttcatct aaataacttc tttcagcagc tcttacgaaa
    13441 aacttacagg ctgctttttc tggaactata tttggagcct ctcctccatt tgaaactata
    13501 ccatgtattc taacatctga ttttacatgt tgtcttagtg catttatccc agcaaaagta
    13561 agttgtactg catctagtgc attgactccc atatgagggt gactagctgc atgtgctgat
    13621 accccttcaa aactaaactc taatgaatct atcgccaaag ccttacagtt tatattatta
    13681 aaagcttcta tatgcatttg ataacttaca tcaacatcat caaaagctcc tgccttaact
    13741 aaatcacatt ttcctcctgt tgtttcttca gctggtgttc ctattagtac aatttttcct
    13801 ttaaaatttt cttttaactt acttaatact atacaagctc ctagtgtaga tgctgcaatc
    13861 cagttatgtc cacaagcatg agctggttct ttattttctc catatccagg aagtgcatca
    13921 tactcagcta aaaatgctat ggtaggtcca tcattatctc ctaattcagc tctaaaagca
    13981 gtctccatat tacaatatgg ataaactgta tcaaatccat attccttcat tttttctact
    14041 aagtattttg atgatatgta ttcttcttcc cctaattcag gattgttaaa tataaaatta
    14101 caaacttctt caatttcttt tccaagttca ttctctatct cataagctct cttctttata
    14161 ctctctatca taatttacct cctactagaa tcctagatat aatcctattg tcaaaaatgc
    14221 cattacaaga attgttaata ctaccattaa aggaattacg aatctaaccc actttgacca
    14281 aggaatattg gctactgcta gtgctcccat taaaacacct gatgtaggtg ttattaagtt
    14341 agttacacct ataccaaatt gataagctgt aactatcatt tgtcttgata catctactaa
    14401 gtcgccaagt ggtgcaagta caggtattgt aagtgatgca agccctgatg ctgatggtat
    14461 taaaaatgct attaatcctt ctattaagaa agttaaattt ataaatatag tttttggtaa
    14521 tccatttaat aaatttgctg cagaatttaa aattgtatct attataaatc cattttctgc
    14581 tattattacg attccacgtg caaatgctat acacaatcct gctgtaatta aatctcctgc
    14641 tccacttata aatgaattaa ctatctcatc ttgtttaagc cctgatgcta ttcctgatat
    14701 tatacctata gctgtaaata tcattgcaat ttcagttatg taccattcta gtcttaaaac
    14761 tccatatatc ataatcgcca tacctattgt gaaaatggct attaccatgg cttctctttt
    14821 tgtaaattcc tttatatttg tatcactatt aaccattaat tcttgattta gtgatatatc
    14881 gtgtactaaa gattttttag ggtctttttt aactttattg gcatacatca taacaaatcc
    14941 tatagatata gccatatata ttataaacat aacaactcta aactctattc cagaacctgg
    15001 tactatttgt gataatgctt gtgctattcc tacagagaaa ggattcgtag tagctgctcc
    15061 aaatccagct gttgctccta taaatactgt ggccactgct gtcaatgaat catatcccat
    15121 actggtcata agtggaataa atatcatata aaaaggtagt gtctcttcac tcattccaaa
    15181 cgtcgtccca cctagtccaa atagaatcat tgaaatcggt attattaaaa attgaaactt
    15241 cttcatttta tttacagtat gagctataac agcttctata gctcctgttt tattaactat
    15301 cccaaaagct cctccaacta ttaaaacaaa tccaactact tcagctgcat ctataaatcc
    15361 gtttataggt gctgtaaata catcagtaat tccttgtgga tttgatggtg ctttttcata
    15421 agttccagct acaacaactg accttccgtc tatatctact ctttcaaaat ttccacttgg
    15481 cactatccaa gtaagaattg ccattaacac tattagcaaa aatattattg taagtgtctg
    15541 tggcatagta aactttttct tttttaaact gctcattttt aatctcccca ctttttaaat
    15601 taaatatttt attattgcat ctctttatcc tattttgtat agatgtaaaa aagctcaaca
    15661 tggatacatg ttgagctaaa tgtgctaaat acaacatacc tgcatcttcc ctttatcttg
    15721 tttaagatag ctctccatca aaattcggga taattttgat gacagtactg tacctattaa
    15781 atacagtccc agcactagct tcggacacta gcacttcggc acttactcct tttatattgc
    15841 ctcattggtt tccaacctct tcaatattaa tcttagtaaa tgcaacctct acctcaatct
    15901 gtttgttaga tgaggtaatt cttattaatt tttattaatt caaagtaatt gtagcataat
    15961 atgtcgagat tgtaaatatt ttcagtataa taattcttac tttatgattt cattccattt
    16021 ttcacaaata attttttctc catataattt aaatactgta gtatatttta aatacacaca
    16081 aactttccac aaattttaaa ttattataat acctttataa taaaaaataa aagctatgta
    16141 aacttatcaa tttacatagc tttatataca ttaatctact ccaagtacag ctttaagctt
    16201 tgatgctatt gtaataactc gtggaccaaa tataacttga actgagtttt tctttttaac
    16261 aactccactt gcacccaatt catttaccca gaagccatct tcatagaatc catcaattga
    16321 atttagctct accctaagtc tagttgcaca gtttgtaaca ttttttatat tattacttcc
    16381 tcctaaacct tctattatag aatgtacaag ctttgtatct ttatcatcta cttcctcttc
    16441 tactgcattg ttgtatgctg ttttaccagc atctacagat tgtctttctc tatattcttt
    16501 cttactataa agcttaactt cttctgaact tcttcctggt gtttttatat caaacttctt
    16561 gattgcccat gtaaatatta tataagtaac tataaaaaat attggtatca aaaataataa
    16621 tggtaacgca tccacttttt gtggttgtaa taaattagga aacatatttc taaatgattc
    16681 tcccattata gaaacattga acatttctgt aaatacatac gtcaatcctg ccagtggtac
    16741 atatgctaca aaatacaata atggtgcaac aaataggaat gtatactcta ttggttccgt
    16801 tacccctacc aacatggctg ttactattgc tggtatcaat atacttattg cttttttctt
    16861 attagcatta tcagccaact tatacatagc taaagctgct gctggtaata ttgcaaaatg
    16921 tattaataaa cgacctgttg tgaagttacg agttatataa gatagtgtat ctgggtctcc
    16981 catttgagct aatcttatat tattaacacc ctcgtaaatt gctccaccta cttccattgt
    17041 tccacctact cttgtatatt ctatagggaa tgcaattaag tgatgtatac caaatggtaa
    17101 taatgcttta tccattgctc caaaagtaaa tgttcctaat aatccactag aacctatcca
    17161 attaccaagt ttagataatg ccaaccctac tggtggccat ataaggtaca ttgctgtacc
    17221 caatactatt gatgctataa acatcataat cattgaaaat cttggacctg agaaaaaaga
    17281 taatgcacta ggaagttcta tgtcaacaaa tttgttatgt actgcactag ctacaaatcc
    17341 agctattata gctccaaata tactacaatc atatgaaaag attcctaaga aagaaccata
    17401 taaagaactt cgactatatg cttctgcctc tcctaatcca gatgccataa acgcttctgc
    17461 tgtaactgta tctgaattta taccatttgc tgctaacaat gtacttataa ctgtgtgcat
    17521 tcctataaat aaaacaattc ctcctaatgc accccatcct ttttcctttt tagataatcc
    17581 aaaggctata cctgtaacaa agaatattgg taaatatctc attaccataa atcctaaatc
    17641 gtttattact ttaaagaata catttataaa tgacccttct tttattagtc cgctaagccc
    17701 taatgcagaa acgttttcca tatttgcaaa agctgaccct aatcctataa atactcctgc
    17761 tacaacaagt aatataacag gtatcatcat tgctccagaa agtacttgta atttatcctt
    17821 catagtatta tttcctccat ttttattgaa atgccaggct atataatgca tatatatata
    17881 cttctattgc tttgtataat gtatctatac ttatattttc atttgcctga tgtgaatttg
    17941 gattatcccc ctctattgtg ggtccaaatg caactccatt ttttaacact cttgcataag
    18001 atgcagctcc ttttgtaaaa agttcggctt cttttccaaa accttgttta tatgcacttg
    18061 ataatttatt tattaattca ctatctggtt ttacatacag taattttaaa tccttatata
    18121 tatcaactat taaattttct ttttttccaa tttcattaat tctattagtt ataaactccc
    18181 aacttatacc cttaggatat ctaaagtcta ttttcatatt caattcattt ttctctaaga
    18241 agatactcat tatacatatt gtagaaactc ccatatctac atcttcttta tatatcccta
    18301 atttttttcc atgattatca tctgtaaagt atgaatttaa aatatccctt attataacgc
    18361 ctttatcatt taatttttta attttctcta aatcttttgc taaactaaat gcacagttat
    18421 atgacctgtg tggatttctc gataaagccc tttctcctgt atatcttact aatactttac
    18481 cttcttctag ttcttctatc tctgtataat aagctaatga ttctactaaa tctttcttat
    18541 cattagtttt aaaaacagcc tcaattttgt cacatacaaa tccatcttct ttgtttgact
    18601 ttatatcaac taaattgtga tttctaaatt tatctttatc tattttcttt cttagattga
    18661 agtataaaat acctttttct ccatttacta ttgggaagtt tccatctgga gaaaatgcaa
    18721 attttggctg ttcattgaca ctaaagtaat gctccataca ttcccaagtc gtctcttcag
    18781 ctccacccac tatcaaccta atctttctct tcggcttttc attaagttct cttaagaaaa
    18841 gtaatgcata taaaatccct atcaaaggtc ctttgttgtc attaactcct ctaccataaa
    18901 gatagttatc tttttgacat actttaaaag gtttactctt ccaaagttct ttattatata
    18961 ttggcaccac atctatatga ttaagcaccc ctactacttc ttctccttct ccatattcta
    19021 tatgaattgc atatccatca aagtctttta caacaaaatc tttgtctttt gctatttgaa
    19081 taagcttatc gaaggcattt cttatttcta tcccaaatgg ttgatttata tctgttgtac
    19141 tttcatctct aattgaaggt atttcaacta aacttctaat atcatttatg atattttctt
    19201 gattggattt taaataatca ataattagtt ctttgtttac tatcatctta attatttatc
    19261 acccctttat attaatttta caaagcattt cagttcatat ctacattata aattttgaat
    19321 attatttttt caatatttca aatacttctc taagttacca taatgatacg gtaaacaatc
    19381 aacagattat gacaaaatca tactatatct attactaata ttttaactta tctattacgt
    19441 cttttttaat gtaagtttat tccaaaaata cataaaaaaa gatgtagcct tagctacacc
    19501 ttcttatatc tattcaactt ccattattat gctattaata tctacatttc caggttctat
    19561 cctatctttt actgttctct taacagaatc agcatcatcc attataacta caggagttat
    19621 tatatttaaa tcatttgacg ttataaaatc taaatctact tccattatta aatctttagc
    19681 ttttacctta tctcctgcct ttaccttaac atcaaacggc tttccttcta gtgacattgt
    19741 ctctaaacct acatgtatta atatatttgt attatcatta ctcttaatca ttattgcatg
    19801 ctttgtatca aatacattga ctatttcacc atcaacagga gaatataact taccttcact
    19861 tggtattatt gctactccat ctcccatcat cttttgggca aaaactgcat ctggaacatc
    19921 ttctaagttc actaaatttc ccttaaaagg gctatatatt ttctcaatct tattttcttt
    19981 tttcttaaat atattaaaca taacacactc tccacattat aaaattttat gataatattt
    20041 ttcttaaagc ttttgctaca ccatcattta cattagtatc agttacaaaa tctgccatag
    20101 attttacttc atctgtagca tttcccatag caataccaag acctgcaaat ttaatcatgg
    20161 atatatcatt ttcattatca cctatacaaa taacttcttc gctatctata cctaatatat
    20221 cacaaaattt tttaactgca ataccttttg aagtaccttt gctcataact tcaaaattta
    20281 tctttccaga acttactact tctaaatctt cttgtttttt aaattcttcc tttgcttctc
    20341 tcaaagaatc tacgttttct gagaaaagta tacattttaa aatttcatta tcagcttttt
    20401 ctaataaagt ttcacaactt gcattttcta ttatttcaat tctgtcttct tctttatttt
    20461 tactatttat taatctatat ggatgttctt cacctatttc attgttggat ataactattt
    20521 tacagccttt aaaatgtttg tttaaattat acttttcacc tattgtatag attttcttta
    20581 gagcttcttt gctcaaaacc ttcttatact catatcccag taatttaaaa tatgtcccat
    20641 tagttgatat aatatatata tcatccccta aaacacttgt aaaatatttc atagcattat
    20701 aaggtcttcc cgtaactaag gctaccttga tacccttttc catgacttct tttagtgctt
    20761 taatattttc ttctgatact tcaaatcctt tacccatcaa agtaccatcc atatcagtac
    20821 aaattaattt atatcgcatt tgtatcacat cctagtaaga tttttctaat atttcaacaa
    20881 ggtcttcttt ctttccaaaa ggtaaaaatc ctaaaactgg acagcttgtt atttgttcta
    20941 attgttcctt tgttacatta aactcagaca tttttgtctt aagtcccact ctctttaaaa
    21001 aactttctat ttcatttcct aaagttttag ctgcttcatc atcttccact ttttctaatt
    21061 cttggtttag cattctcgct actttggcaa atttctctat attatcctta tagaactttt
    21121 ctgcaaattt tgggaacact atagccaaag cctcaccatg aggaatatgt gtaactcctc
    21181 ctattatttc acttagtgga tgtggtgctg ctgctccagc atttgccagt gaatttcctc
    21241 ctaatgtatc tgctactgct aactttgttc tgtattctat attattttta tcttccatta
    21301 ctttaggtag atagttaatg actaattcca tagatttttc agacattatc tctgtaaaat
    21361 cattagcatt tggatttata taactttcaa atgcatgagt aaaagcatca aatgctgttg
    21421 atgcagtaat tctctctggc agagttaaca taagctctgg gtcaactata cattcttttg
    21481 agaaacaatt ttgatgaaat attgtatttt tctcgcttcc tctcgatatt actgctgctt
    21541 gtgtaacttg gcttcctgtt ccagaagtag ttgatacagc tattaatggt aattcttttt
    21601 cacttacctt atcgtatatt ttaaatggat ttgtatatgt actaaacata taatcccaat
    21661 ctatcttttc taaaccaaaa gtcaatgcta atacttttgc agtatctata cttgaacctc
    21721 ctccaacagc taaaacaaca tctacagatt cttttttagc taattcaaac ccttcattta
    21781 ttaattctac agttgggttt ggctctactc tctgaacctc ccatgactaa agtcacaggg
    21841 ttcctgcttc acagaatttt gcatactaaa atatgtctta
//
LOCUS       DAEOTL010000071        20752 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEOTL010000071 DAEOTL010000000
VERSION     DAEOTL010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.071"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(240..1259)
                     /locus_tag="KRH82_002919"
     CDS             complement(240..1259)
                     /locus_tag="KRH82_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBG8656186.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(1256..1825)
                     /gene="mocA"
                     /locus_tag="KRH82_002920"
     CDS             complement(1256..1825)
                     /gene="mocA"
                     /locus_tag="KRH82_002920"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBG8656187.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(1932..2654)
                     /gene="yqeC"
                     /locus_tag="KRH82_002921"
     CDS             complement(1932..2654)
                     /gene="yqeC"
                     /locus_tag="KRH82_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBG8656188.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSLINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(2837..4114)
                     /locus_tag="KRH82_002922"
     CDS             complement(2837..4114)
                     /locus_tag="KRH82_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBG8656189.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(4253..6559)
                     /locus_tag="KRH82_002923"
     CDS             complement(4253..6559)
                     /locus_tag="KRH82_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8656190.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(6552..7346)
                     /locus_tag="KRH82_002924"
     CDS             complement(6552..7346)
                     /locus_tag="KRH82_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBG8656191.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDKKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(7453..8811)
                     /locus_tag="KRH82_002925"
     CDS             complement(7453..8811)
                     /locus_tag="KRH82_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBG8656192.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSILLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(10159..11208)
                     /locus_tag="KRH82_002926"
     CDS             complement(10159..11208)
                     /locus_tag="KRH82_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656193.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEINVLKEDMSEMKQEMTVMKEDMSEVKQEINVLKGDMSEVKQ
                     EMIVMKEDMSEVRQEINIMKEDMSEVRQEINTMKEDMSEVRQEMTVMKEDMSEVKQEI
                     NVLKEDMSEVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEVRQEITV
                     MKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLECEDKSMK
                     EIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDLNLVELA
                     TSKNWSDIVKLKSVK"
     gene            complement(11438..12523)
                     /locus_tag="KRH82_002927"
     CDS             complement(11438..12523)
                     /locus_tag="KRH82_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBG8656194.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(12559..13872)
                     /locus_tag="KRH82_002928"
     CDS             complement(12559..13872)
                     /locus_tag="KRH82_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBG8656195.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(13873..16164)
                     /locus_tag="KRH82_002929"
     CDS             complement(13873..16164)
                     /locus_tag="KRH82_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8656196.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(16154..16948)
                     /locus_tag="KRH82_002930"
     CDS             complement(16154..16948)
                     /locus_tag="KRH82_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBG8656197.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(16987..17433)
                     /locus_tag="KRH82_002931"
     CDS             complement(16987..17433)
                     /locus_tag="KRH82_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBG8656198.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(17505..18911)
                     /locus_tag="KRH82_002932"
     CDS             complement(17505..18911)
                     /locus_tag="KRH82_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656199.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(18929..20299)
                     /gene="hydA"
                     /locus_tag="KRH82_002933"
     CDS             complement(18929..20299)
                     /gene="hydA"
                     /locus_tag="KRH82_002933"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBG8656200.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(20432..>20752)
                     /locus_tag="KRH82_002934"
     CDS             complement(20432..>20752)
                     /locus_tag="KRH82_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBG8656201.1"
                     /translation="VEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDS
                     EITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFVGTEGYYGILKS
                     VYGK"
BASE COUNT         6279 a         4021 c         2157 g         8295 t
ORIGIN      
        1 actaaatttg tgaaatattt attaaaataa tactaaaaat tgtaaattta taaaaattaa
       61 caatctctta tattatactt ataaagaaat caaattgcaa ctttattcat tcttttacac
      121 attgaaaata agttattata atttctaaat aaatatgctt ttcttaaaac atcattctag
      181 ctgttttgtt tcatatttaa aaagagtact taatttgtaa atactctttt ttaataactt
      241 tatattttag caaaattaca tgcaggataa gtacatacat cacagttcat acaaaggcca
      301 ccatgaccat atctagctat atcatactta tcaagctttt catcaattaa aaccctagat
      361 aaaactatat caaatactgt agttttgtga tacattgcgc atcctggtat acccataatt
      421 ggaacttctc cataataagc aagtaaaaac atagctcctg gtaatattgg tgaaccatat
      481 gtcactaaat cagctccagt ttcttttata gctgttggtg taacatcatc tgggtctaca
      541 ctcatcccac cagtacaaca gataagttct gctccttgac ttataaattc ttttattgca
      601 ctctttataa tctctttatc atctgggcat atagtctgtc ctataacttc acaaccaaag
      661 ccttttactt tttcttctat tacgggtcca aatttatcaa caattctgct ataaaacact
      721 tcatttcctg tagtaacaat tcctactttc ttaggtttaa aaggtactac atttactatt
      781 tttctattac caactacttt ttttgcatct tctaattttt tctcatctat aaccaaaggt
      841 atcactcttg ttccagctac ttttaaacct ttatttacta taaaattatt atgaagagta
      901 gccatcatta tttctccaac acaattcaaa tcaaaaagtg catcaacatc tatctttaat
      961 agaccatcac atgctgctat aaaatctatt ttcccttctt ttatttcact aaaatctaaa
     1021 ttttctccag cagttagttc ttttaaaaac aatgcgcctt cattttcatg aaccattcct
     1081 tctgactttt cccatacata caaattatct ttaccaagag ataataacac tggaatatct
     1141 tcttctttta ctatgtggcc ttttttaaat tttcttcctt taaattctcc aggtattatt
     1201 tgagttatgt cgtgacataa aacttgtcca acagcatcta tagtttttat tagcttcata
     1261 atttaccccc aattctctca tagtccattt ttgtatcgat atcaaataac atttctttag
     1321 gaacttctac atactttatt tttgatgaat tttttaaaat ggttttacct ttttcatctt
     1381 ctttaagtgc caacaattct tctttcttgc tatatgggaa tatgactgga tttccacaca
     1441 tatctttgta tcttggaatt actataaaat ctctatctaa tttaaaagta tttataattt
     1501 tatctatata taagttatca ataaatggct ggtctcctac aaagaacata taaccatcac
     1561 attttgagct atttaaaact cctaatttta tagattcact ttgacctata tttgcatttt
     1621 tattatctat atattcaaaa ccatatttat tacacaataa caaaacctct tcatattgac
     1681 ttactactac aacttgatga aaatcaatct tgctaacttc tctaaataca tgttctatta
     1741 tagaacagcc tttataattt aataaaagtt tatttgctcc cattcttctg gcaaagcctg
     1801 atgccattat cactgcattt atcatatata tcatccttgg tatttataat atattgatag
     1861 ttctatgatt tttataatat ctctattgat attatctata tatataatat catataaact
     1921 attttaatac ttcaatatct tacacaaaat ttttgtttta cacttccata aaatatctct
     1981 atttcacttt catattcttt aatattttct attaatttta tagctaaatt tttatatttt
     2041 tcattttcaa ctttattaat aaataatact ctttttccag aataattttt aaataatcca
     2101 tttggattta atactatatt ttttaagttt tcaatactta ctgtagaact actattaata
     2161 ctacttgtat ctaaatttgc tattttttta aatatttcta ctctatgtat attctcttca
     2221 ttaatattca ttccaaatga tgttatatct aatatcccta tggtttttgt agttttatga
     2281 tatactactg gttctttagc attccaacct ttaagttttt ttctctttga gccatctccc
     2341 tctattaaaa ctaaatcaaa ttggtctaca atttcatcca aaatagagga atcaatactt
     2401 actaatttat tttcattatt tatataactg ccacagactg ttattccatg acaaatagat
     2461 ggaataacag ttccatctat tgtaataatt atattgtcat aatcgtttgg tacatatatt
     2521 ttagttgttg ttgtaaggag aactttcaat ttatctctat aaaaatttgc aaaatagttt
     2581 ataagcgaag tttttcctcc tgctccaact acagttatta tttcattctt ttctattata
     2641 tttgatagtt ccacactttc acctcttata accagttttc taatctctta attattatag
     2701 ttagaccttt ttagtaaaag tgatttttga aattccataa actcgaaagt aaatagattc
     2761 tgttgtaaac aacaaggcgg atccaattcg ccgctaagct gtaagcttac gctatcagtt
     2821 tatcttttaa atataattaa gatattctta ctctctgtgg ttgctttaat atttgaggat
     2881 tattctgtaa attagataaa ttaactactt gtgatttttt tagtatatta agactcgcat
     2941 ttacatctgc atttataatg attccaacac tggatttgta ctgtccacgc gttattcttt
     3001 cccctttaaa gtcatatttt ttaacattgt ccacattgat atcaggtaga aaatcatcag
     3061 caaaaaaatc tgatttacta gtatagcttt cttcttgcct aataaaattg atatttttta
     3121 ttttacacag atattctaat tttcctttta tctctccaaa tgggattctt ataaaatttc
     3181 tatatatttt tctctccata ttatcacttt tttctaactt agcattatat cctacaatta
     3241 aatttccaat attatttttt acacaataat caattatata aaaacaggtt ttatttacat
     3301 agtctttaac ttgattattt ctcttattcc aaactttaaa ttgttttctt gttattgcag
     3361 ttatattctt ttttaatttt aaggcttcta ttttatcatt ctgtttgttt gcccactgat
     3421 tcacagattt tagccttttt ccatctatga taaaactatc acctaaattg gtaacacatg
     3481 tacataaatt ttctaaaccc aagtctatag ctagtgcatt tttttgattt gaaacttcct
     3541 ctgattttgg tatttcataa caatactgaa tttcaaagaa cctagcttta tgtttaggta
     3601 ttattcttat ttctttaatt tttttctcta gtatattttg tggaactttt atacttactt
     3661 tcccatatag ttttttaaat gctggagaca taggtacatt taaaatccca tcttctttga
     3721 ttcttatttg acctattatt atgctaaaaa atccttcttt atctaaatat ttaggtgatt
     3781 ttatccctct aaagtcatat tttccttctt tggctaattt aattaatcca aaaaatgacc
     3841 taaacgaact gtctacttct tttaatattt gttgcgctat attactattg agaagcttat
     3901 agttctcatt ttctttgcat acatgataat tagcttcata gttaagatgt tctccttgat
     3961 tgaaataatg ctgtcttaca ttatatgtac caacattata taagttctta gctaagaagc
     4021 acatttctcg tagagcttga tattcttttt tagttaagtt ttttaattgt tgtctctgag
     4081 ttccatagtg tatatttttt attctgtttg acatgaactc acctccttta gaatatactc
     4141 tactagacat tatatacggt atttttacaa aacaccatat ataatgtcca tttaattact
     4201 ttattttaca aaataattta aatttacttg cttttataca tcttattatt tattataatt
     4261 gtttattatt atttttcata cccatataaa ctttttcaaa agtcatagga agctctctta
     4321 aacgaactcc tgtagcatta aatattgcat ttgctatagc tggtgctggt gtatgtataa
     4381 ctatttctcc taatgattta gcaccataag gacctcctgg gtcgaaattc tcagcaaaat
     4441 ctaccaatat atttccaact tctttttttg taggaacttt atactgtagg aaactatctg
     4501 ttaataatct accatcttta tcaaatatag ggtcttcata cattgcaaac cctataccca
     4561 tcatcacacc accttctact tgtattctag ctaaagttgg atttataact gttccacaat
     4621 caggtacaca tgcaaaattt atgactttat attcgcctgt atttttatct aattctatct
     4681 ctgcaaatcc tgctataaat ggttttattt ttttcaacat gccaaaagat tctgttgctt
     4741 ccaaaactac tggtacatca tcactagcaa atcctattcc tccaacagat tctctaccca
     4801 attcctctaa tagaacaaac ttgctattat cgtttttaac aaaaaccctg tcttttccca
     4861 actctaaatc ttctttttta aatcctagct ttgactctgc aactgaaagt aatatatctt
     4921 ttaatttatt tgctgtcttt attgttgcat ttcctgtaac cgttgtcgta caagaagcaa
     4981 atgctcctgt atcataggga cataagtctg aatcacctgt ataaatagaa attctatcta
     5041 cagtagtatt taaagcttcc gcagcaattt gagcttgaat tgtatcagcc ccttgaccta
     5101 agtcagcaag accagataat agtttatatg tgccatcttc atccattctt atagtgactg
     5161 ttgccatatc tacacgcggt ataccagaac catgatttgc tactgccata cctactgctc
     5221 ttactttgtt gtttcctata tctttacatg gatatttatc atcccaatta attaatttct
     5281 tgcccttttc tatacattgt ctcagctcac aacttaatat ttcgtcttca gctgcttttc
     5341 cattggtata cctatctatt atatttttaa ttctaaattc aagtggatcc attccaatct
     5401 tatgtgccaa ttcatcaata gcactatcta ttgcaaatat tccctgtgta gcaccatacc
     5461 ctctaagtgc tcctgctggt aacctattag tatatactgt tctagcatta aatctaacag
     5521 catcaatatc attatatatt ggtaaggtat tgtgtccaga ttcggaagaa acagagacac
     5581 cattcccacc ataagcacct gtattgttta atgactttag ctctattgct tttaaatttc
     5641 cttctttatc tgcaccaact ttaacatcaa aaaacatttc atgtctacta ttagaaccta
     5701 caaaagtttc acttcttgta aatacaaatt ttgctggtct accagttttc atagtaacaa
     5761 atgcagtaaa tatatctgtt gctgctatat tctttcctcc aaatccacca cctattctag
     5821 gtttaattac tcttattttt gaagatggta tacccaatac ttttctaagt attctcttta
     5881 cattgtgtgg tgattgtaat gatgaaacta caacaattct atcatttata tctttatatg
     5941 aatatgacct atgagtttcc atcatgcaat gcgattgact ttgggttttg tatgaagatt
     6001 caaccacaaa atcactttct ttaagcttag cttcaacatc tccaaattca aaaaattctt
     6061 ttgatactat attatttttt gcatccaatc caaaagggta tggctctact atgtcttttt
     6121 ctggatgtat aacaacttca tttccttctg cttctcttgc atcaaacaca ggctttaaaa
     6181 cctcataatc tacctttatc atttttaagg ctttaagtgc cgttttctca tcttcagcag
     6241 ccactaaagc tacttcatct ccaataaatc taactgtatc ttcaagtaaa actctatcat
     6301 aaggtgatgc ttctggttct gtttgacctg gcacacaata tctgacctgt ggtacatctt
     6361 tatacgtata aatacccaca acccctggaa ttttttcggc ttttgatgta tctatattct
     6421 ttatcttagc atgagcatgt ggacttctaa gtagttttaa tgtcaaaaca tctttatgca
     6481 taatgaggtc ttcagtatat agaggttttc ctgtgacaat tgctgtacta tctatctttc
     6541 ttatcccctt attaatcatt atacattccc tcctcaatag cattatacat ccttttaact
     6601 aatgcacttg ccatatcctt tctgtactct ttactagctc tcatattact tccataagta
     6661 agttccttac tagcaacaat agatgcctta tctatatctt tttctttatt taatatatta
     6721 ctcgcttcaa gtgctaatct agctttttga ggtcttgccc caattgctat tttgtaagta
     6781 tcattttctt ttagcattgc tgaatttaat acagaaaaat ctcctgtgca ttttcttatt
     6841 gagtcaaaaa cagctattgc atcttttttt ggtagtatta cttcgaccaa tatatcccta
     6901 cttaattcac tatccaaaaa ctcacttaac tctagtattc ctttattgta taatctcacc
     6961 ttcgctccaa caaccaaaag cgctggtatt aagtcagaaa agccatactt tgaaaataca
     7021 cttgcaccaa ttctagcccc ttgtctaaat tgaacaccaa ctatattaga aacagcgctt
     7081 gaaagtattc cactacagta attttttata gttttatcaa tttctaaact tctaagtgaa
     7141 gtatctgcac ctatcaaaat atttttttta tcctctttta tataatttag atttatatct
     7201 tttaaatcta tcgctgttcc tatattttta ttacttaatt ttataaatcc acatccacct
     7261 aaaataacat tatttttttt agaaattaaa attttatatg cttcttctaa actctgtgga
     7321 actgaatatt cctttatagt aaccatctta tccccccatc attaacttat taaaacacaa
     7381 aagtttttaa taaatctttt atttatattt ataattgtag tatatttaat tcacatatat
     7441 taaaccttta cattataaac ttttattttt atcctcaacc ttatcacttt tatttccagg
     7501 aaattttacc atatataaag cttgaattat tatggctacc attgctcctg aaactacact
     7561 tgaatctgca agtaatgtct ctataaattt tggaaatttt tcaagaactt gaggagctac
     7621 catgaatcca ataccagaag ccatagaaag acctaatatc atgctatttt cttgattaaa
     7681 tccatccata ctaacaagtc ttaaaccaga tgttgtaaga gttgaaaata taacgagtgt
     7741 tgctcctcca accacacagg gaggaattgt tcttattaaa ttagctaata aaggcgatat
     7801 tcctgccaaa aataatccaa ttcctccaat agctagtaca aatttactta caacctttgt
     7861 attggaaacg attgcagaat tttgtccaaa catccccatt ggagttgcag aaaataatgc
     7921 acctattgta gagagtactc catttcctaa aacagcagaa gaaagttctt catctgttac
     7981 ttgtctatta agccctccta ccgcagaaag tgtacaagca cccattatat cagctatctc
     8041 aactaaatat attattgaaa acattacaac aacttcaagt cttatatcta gcccaaaagc
     8101 aagtggtttt ggaagtgcaa ccaaagtaaa ctcctgaatt gaagaaaaat ttactatacc
     8161 caaaattaat gataaaatgt atccaaaaat tatgctaact aatattgatg catctttaaa
     8221 taatcctttt ccatacttat ttaatcctaa tatcataaga gatacagata ttccaactat
     8281 aaaattaatt ggattcccaa aagtctcatt gcccataccc ccagctaagt tttttatagc
     8341 tattggaaaa agtccaagac ccatacatgc aactattgtt cctgatacag ctggagtaaa
     8401 tataaatcgt atttttttaa gaccaaaacc aattataatt attactatac cagctattat
     8461 ttgagagcca aataatactg gtagtccata cttacttgca acagataccc cagctcctat
     8521 aaacatagct gtagctccca ttataactgg tattcctcct cctaatttaa aacctttaaa
     8581 caaaggtatt ggatataatt gtaataaagt tgataatcct gcaaaaacta atgcggcttg
     8641 aatcaataat attgacatct tatgattaag tccagctgca tttgcaatca atatcgctgg
     8701 taaacaacta cctattacca ttgccattaa gtgttgtaac cctaaaggta ttgcttcctt
     8761 tagtggtggt attccgtcta attcaaattt tgatgtactt tttgctttca taataaaaac
     8821 tcccgttaca taaaacttat tgaattatat aaatacttaa aaatctaata tattaaatta
     8881 atgatgttca taaatatcaa ctatactcca acatatattt aagtttttag tcttaaaaaa
     8941 cagatgcaat aaatttaatt attaacaaat aaacgtattc tttaattttg tatacattat
     9001 ataccatgct ttacaaatat aagagtatta tagctatgaa tttttaattt tttatagtaa
     9061 atttaattca atttaaatct ttcaatctta atcattataa gttataagtt ttcataagta
     9121 tttacatgtt tcaagtttta aacatttacc tataaacgct actttataga tgtcacttca
     9181 aatccagtga cctcatactt tcatatgagc gtagactatt tcttcatctt cagcattacc
     9241 tgctaagagc aacccgtttc cactatcaat cgcttatagt gtactctctc tcgagatagt
     9301 cgtttgacct tcctatttct aggcttggcg accaaatgtc catttttaag tacttaggct
     9361 ctcaccatat accatcctca ctattgtttc tggttttcac cacattcata aaagtttctt
     9421 tctatctttt attgtagttg caaggcttta ggatttactg gttttaaagt tgtgtcctac
     9481 atagatttct ctatgtacgg ggccaaaagt acaatttatt taacatactt tgctttaccc
     9541 cctgtaaata atattattta ctctttcact gtttttgtta ttaaattaat taaatatcaa
     9601 ttaatctaag cataaaataa ttatttaatt taaactcaaa atatttatga atattttata
     9661 atataattct cataagacag aaaaacttaa taagctatgt atctcagttg taccaatgta
     9721 ctctccttta ctatatttgt atctgcaaca taaaatatac aagtttctat ctatttatag
     9781 atatatatat ctataagcaa aatagtaata ttatttttaa tagtaaaaat tttattcata
     9841 ttactattta taatttttat agagcaattt tagtgccaat atttgcatac atttgtatag
     9901 tataaaattt ttatgttctc attgataaaa ttttacttat ttcaagcgtt ctattagatt
     9961 ttatcatcta aattttaggt tttattttta taaattaatt gtatttacat aaaaaaaaag
    10021 acctaaaaac aaatttttaa cggtcttttc tcaatttttt attttcattt ctaaaattta
    10081 taataaatag taagaacact ataaattctt ttatataaaa ttcttagttt gtggatgata
    10141 aattagtgaa ttaaaatact actttactga ttttagtttg acaatatcac tccaattttt
    10201 actagtggct aactctacta aatttaagtc tcttcttatt tcagctatat cctcttttat
    10261 agaattagtg tcacctttta tatatgctat gttatgttct atattatcat gagtagcttt
    10321 atttatttca gaattatgta ataaacttcc taaaatatta ttctgttcta tctgtatctc
    10381 tttcattgat ttatcttcac attctagact atcaatctta atttcaattc catataattt
    10441 ttcatttgct atggatacct cgtccttaat tccattcata tcttcattaa tgttatttat
    10501 tttattttgc ataaagttta cttctgattt aacttcggaa acatcttctt tcattacagt
    10561 tatttcttgt ctcacttctg acatgtcttt tttcattaca tttatctctt gttttacctc
    10621 tgatgtatct tctttcatta cagtcatttc ttgtcttact tcggacatat cttctttcat
    10681 tatatttatc tcttgtctta cttcggacat atcttctttt aatacattta tctcctgttt
    10741 tacttccgac atatcttctt tcattacagt catttcttgt cttacttccg acatatcctc
    10801 tttcattgta tttatctctt gtcttacctc ggacatatcc tctttcatta tatttatctc
    10861 ttgtcttacc tcggacatat cttctttcat tacaatcatt tcctgtttta cttctgacat
    10921 atctcctttt aatacattta tttcctgttt tacttccgac atatcttctt tcattacagt
    10981 catttcttgt ttcatttccg acatatcttc ttttaataca tttatttcct gttttacttc
    11041 cgacatgtct tctttcatta cagtcatttc ttgttttact tccgacatat cttcttttaa
    11101 cacatttatt tcttgtttta cttccgacat atcatttttt atgctaacta catcttcatt
    11161 tatagtatat aataactcta aaatcttctc ttgcacttgc atcaccatcc ctattaatta
    11221 ttataacatt ttacacaaat gctatacaat gttaacatat atatcagaat tattaaaatt
    11281 ttaattaaac aaaattgatt cactttatta cttcaaaact aattaatatc taaaataact
    11341 acaaataaac aaaaataagg tcaacaacaa aaaaggctta tctctttgag atagcctttc
    11401 ttatttttat ttaaaacttt gttttttata aaataatcta tacattcagc tctgaacatg
    11461 aaatttttct tccaagtgct tttggtttac aaactgatat acaaagtcca caatatctac
    11521 actcttcttc attcaattcc atcttatcat tcaattttct cgcttgatat gcacaaactc
    11581 tctcgcacat cttacattta gtacattttt cttcatcata agtaaactca aagctaagtc
    11641 tttcattaac atctcccata tgattatgta ctataccaca agcattttct atagtattat
    11701 atcctaatct attaagatta gattttaaat catcatgtat tttagatatt acttgtgcac
    11761 cttttaaaat tactactgaa catataccaa caaagtcagc acctgccata atcatttcta
    11821 aggcatcatc tccacttaca catccaccta agccaattat tggtatatta acttgttttt
    11881 ttatttcata tattctctgt aaagttattg gcttgatagt ttctccactt aaatatccta
    11941 ttccatttcc acctaataaa ggttgccctg tttctatgtc tattctaaat gctggtccta
    12001 cagagtcaca agcagttatt gcatctgctc ctgcttcttc taatttttta gcaaaatcgc
    12061 ctatctcatc tatcatagga ggaagtttaa ctattacagg tatatttact ctttcctttg
    12121 catctttaag cattggtatc aaatctctat agtcataaga tactaattca ataaagtcag
    12181 ctcctgcatt tgcaactttc tctactaatt cgctactttc ttcaattgta tgacctattg
    12241 aagctataca gacagtccca tctcttttca tttgtggtat ttcaaaatct atccattgct
    12301 ctggctcaaa atctgtccat ttttcattat ttaaaagagc attagctgta tttctaacca
    12361 tatgtggtgc tggatttata gctctttctt ttcttatagt cttagtcaca actgcccctg
    12421 ctcctgcatc acttaatatc ttgcatccag ctgcactata tgttaatggt cctgaaccta
    12481 ttataagtgg tgattttaat tctttaccta aaaaattata cattatctgc ttcccctttt
    12541 catatatatt tacattcgtt aaaatttcca aaattcacaa gcaacttctt tcatttcttt
    12601 aacaatagct tttttatcta aatcaactaa ctgtttttct tttaaaatat gtctaccatc
    12661 tatgtataca tttgatataa attctttttt accctgaact actatctggt caaatatatt
    12721 atcaagagtc acaggagttt taaattcatc ttccataact attatatcag ccttattacc
    12781 aactgctatt ttaccagaat tttgaagtcc taatacataa gcaccatgct ctgttgccat
    12841 tctaaatact aaatttgctg gcattactga tgcatcttct tcaactgatt tatgcattaa
    12901 aaatgcacct ctcataactt caaaaaaatc atttatatat ccatcagtac ccagtgccac
    12961 ttttatgcct tttttaatca tttttggtac tggagaaaaa cctccaccta cttcacagtt
    13021 actaagaggc atatgaacca cttttacgcc tttttctttt aatatatcta tttcttcatc
    13081 atttactttt acacactgag atgctaatac agtttcatcc aatatatcta aatcattata
    13141 gtagtcaact gcttttttgc caaagtgttt ttcagcatag tttggctcat atatactctc
    13201 acataaatga aattgcattg gtgcatttaa tttttttgca tcttctttag ctttcttaat
    13261 aaatctatca gaacatgtga agcttgtatg tgtacacatt attccattta ttaatttact
    13321 attttctcta ctccacttta ttaaattaga attttcatct aaacatctaa gtccattttc
    13381 aaagcttatt ctttcacaac tttctaagga taaaatcgct ttcatgccta tttcttctag
    13441 tatttttcct tgctcaatta aagttccttc ttctgtattt ggagcttcta gggtatcaca
    13501 aaaagctacc acaccagatt ctataagttc tattgctgat gctttagttg ttgccttcac
    13561 ttcttttaat ccaattctat tttctataaa tggccaccaa tagtcattta aaaaaccttc
    13621 aaagtcagta aaatgtacat ttgccggtat tcccctagaa agaactccat attgatgcat
    13681 atgaccattg acgaatcctg gcattattat agcatctgat ttatctatta tttcttcaat
    13741 atttttatat tttatttcaa cttcttcatt tggcaatata tcttttataa tgtcattttc
    13801 tactacaaca gcagaatttg tatatatttc atcagcagaa gatattaagt atttactttt
    13861 aatagcaatc atttatttac ctccctgatt taattttttc atggccatat aaactttctc
    13921 agaagttata ggaagttctc ttatacgaac tcctgtggca ttgtatattg catttgctat
    13981 tgctggtgca ggtgtatgaa taactatctc tcctaaagat ttagctccat atggacctgt
    14041 tggctcataa ttatctacaa aatcaacaat tatgtttcct atatcttttt ttgttggaac
    14101 tttgtattgt aatagattag aagtttgaag ctttccatca gaaccatgtc tagggtcttc
    14161 atacattgca agccctatac cttgagttac accaccttca acttgtattc tagcaagtgc
    14221 aggattcata acggtaccac aatctgtaga acaagcataa tttattactt taaactcccc
    14281 tgttgtttta tctaactcta tttcagcaaa tcctgctaag aatggtttag cactctcttg
    14341 tataccataa gattcagatg aatataaaac ttcttgattt ccaccaccaa cagattcttt
    14401 tcctaattca cttaacaaaa caaacttctc tacatcttca ctataacaaa ctctgtcttc
    14461 atatagtatt aaatcatcta ttggtaaatc gagtttcttc tgtgctactt ttaatatctt
    14521 ttgttttaaa ctttcagcag attttattgt agcatttcca gttacataag tagtacaaga
    14581 agcgtatgca ccagtatcat atggacacat atctgtatct cctgtataaa cggaaattct
    14641 atcaatagat gtattcaatg cttttgcagc tatttgtgca agtattgtgt cagaaccagt
    14701 tcctaagtct gaagacccag aaaacaactt ataagttcca tcttcatcca tcctcatatt
    14761 tactattgcc atgtctatgt tggctatacc agaaccatga gttcccacag acattccaac
    14821 agccctcacc ttattgttgc caatatccct aacagggtac ttttcatccc atccaataag
    14881 ttttttacct ctaattatac attcatcaag tgcacaactt cttattggaa aattcattat
    14941 tccgccttca gtttgttttt ttataatatt ctttaacttt atttctgttg ggtccatatt
    15001 aagtttatgc gctaattcat caattgcaca atcaagtgca aatgtacctt gtgttgctcc
    15061 atatcctctt aatgctcctc ctggaactaa attagtatat acagttctcc catcaaattt
    15121 tattgcaggt acattattat atgttggaag tacattatga cctgattcag agcaaactga
    15181 aggtccatta tcaccataag cgcctgtatt gttcaatgct ttcatatcta tagcttttat
    15241 gtttccttct ttatctgccc caatttttat atcaaaaaac atctgatgtc tagtattagt
    15301 cattgcaaaa gtttcttctc tagtataaat tagttttgct ggtctttttg tcatccaagt
    15361 tacaaatgat gcatatatct ctgttacagc tatgtttttt ccaccaaaac ctccacctat
    15421 tcttggtttt attactctca cttttgaaag aggtattccc agtgctttag aaacctgtct
    15481 tctcatatga taagctgatt ggtttgcaga agttactact aatctgccat tcgtatctat
    15541 atacgtataa gctctatgag tttccatcat acaatgggct tgtgattgag tcatataaga
    15601 atgttctact attacatcac tttctttaaa ctctttttct acatcccctt tacccatttt
    15661 ttctctcgat acaatatttt ttgtagcatc caatccaaaa tcaaatggac aaaacaaatc
    15721 atcttcttca tggattaaaa ttttatttcc ttccgattct cttgcatcca atataggagt
    15781 cattacttca tattcaactt ttataagttt catagcttta atagcagccc tttcatcttc
    15841 agcggctatt atagcaactt catctcctac atatctaact acgtcttcaa gtattaattg
    15901 gtcatgaggt gatgcttctg gatatgactc tccaaccatt gaatatctat aatttggaac
    15961 atctttgtaa gtgaatatgt ttactacacc ttttaccttt aatgcatttt ttatatctat
    16021 gttttttatc ttcgcaaaag catgtggact tctaagaagc ttaattgtta aaacatcttt
    16081 atgaaaaatt aaatcttctg tatatattgg ttttccagta acaatggctt cactatctat
    16141 ttttcttacc tctttattta ccatcacact cacctccaat actattatac attctcacta
    16201 ctaaggcttt tgccatatct tttctgtatt ctttacttcc tcttatatta cttccaaatg
    16261 aaagttcttc acttgatact tcaccagctt tttctatatc attttctaaa cttaatattt
    16321 cacttgcttt ataggcaatt tttgctcttc ttggtctagc gcctattgca attttataaa
    16381 tacttccttc ttttaacatt gctccattta atactgcaaa atcacctgta cattttctta
    16441 tagaatcaaa tacacctata gcatcttttt taggtaatat aacttctatt aatatatctt
    16501 tttcaagctc actttctaaa aaatcagcta agttcataac ccctttttta tataacttaa
    16561 cctttgcatc taccactagt aatgaaggta ttaaatctga aaatccatac ttagcaaata
    16621 cgctagctcc tactctagct ccacttctaa attgaactcc tactatatta gaaacagcgt
    16681 ttgaaattac cccattacag taatttttaa taaccttatt taattctaaa gttcttaaac
    16741 ttgtgtctgc tccaattaat atgctatcat cagtttcatt tatataatct aaagctaagt
    16801 cttttaaatc tattgctgag ccaatatttt tactacctag ttttaaaaat ccacatcctc
    16861 caagtattat gttgtttttt cttgatatta gcagttcata agcttcatct aaactttttg
    16921 gaactacata ttcctttata gttatcatac tctctcccca tatcaactta attttcactt
    16981 aaaagtctaa gtgtttaaat atttatgtat tgctcttaat tgacctttat atcctgtaca
    17041 tctacaaagg ttaccattta cataatctat aacttcttct tctgttggat tttgaagctc
    17101 tcttttcatt gccaaaacca tcattataaa tccaggagca caaaatccac actggtcagc
    17161 cccttcgtct gcaagaaaat ctccaaactt ctttgcttca tccaagacac cctcaagtgt
    17221 tgtaatatgc tgaccgtcta ctctagcagt aagataatta catgaaagca cggccttgtc
    17281 atttaccatc actgtacata acccacatga gcctgtatca cacccttttt taacacttac
    17341 atatccattt tctcttaatg tatctgctaa aaaatcatct ggtcttatac ttaattcttt
    17401 ttctttatta tttatggtac atttgataat caaataaatc acctcaaaac tcatattttt
    17461 aagctaaagt tttactatac ttttctatga ataaattaca tttattaata aaggctattc
    17521 catttatgac cttccattct attttttata gttcctctta cacaaagtct ctcagctgta
    17581 tcttgagcat cttttaatgc tttctcttca ttagctgtca atatttttga atcttccatt
    17641 attatatttc catctactat aacactctct atatttttca tactagaaga atatactaat
    17701 gtagataccg gattatgcat aggtatcgct tttggtgaaa gcattggatt aaatattagt
    17761 aagtctgctt ttttacctat ctccaatgaa cctatctcat cttccattcc aatagctctt
    17821 gctccatcta tagttgccaa ctcaagaact ttttctgctg acattgctaa tgggtcacac
    17881 ttattaactt tatgttgaag tgctgttaat ttcataagtt caagcatatc ttgagagtta
    17941 ttactagcgg ctccatctac tcctaaacta actgttattc cttttttaag catttctggt
    18001 actggtgcaa cacctgaaga taagtacata ttacttgctg tattatgaga cactttcata
    18061 tcgtattttt tagtaagttc catatctttt tcagttagat acacacaatg taccataagc
    18121 acatttggtc caagtattcc taatttttct aaaacatcta tgtcatattg cccatgcaat
    18181 tcttttgctg cttctctatc aaaaggagtc tctgatatat gtactgtaaa taaagcatca
    18241 tcatattctt ttactactct ccatagcatt tcaagcattt cttgagaatt tgaccatatt
    18301 gctgcaggag ctactcctat tttgattctt ccattttctg tattatggtg tttttcaaac
    18361 aatcttctta catctttttc aaccgtttct acatcttgca ttattccagg atgaactcca
    18421 aattgagctc ctgtattcat acatcctctt ccaagtattc ctcttattcc taattcttta
    18481 taagcatcta ttattccatc acaaagacct ggcttactat gaggatacat gtagtcaacc
    18541 attgttgtta taccacttct aagtccttca atacatccaa gcattgcagc atcataagta
    18601 tcttttggct ctaaatagtt agctgctgga aatgtcatag tttctaacca gtctttaagt
    18661 accatatcat ctcccaatcc ttttaataaa gtttggaata aatgattatg tgtatttata
    18721 aaacctggga ataaaacttt acctttagca tctataattt ttttaacatc agtatattta
    18781 ctttctatct ctttagaatt tccaatatca gcaatcttgt tatcttttac tactaatgcc
    18841 ccatcaaaaa taacttctct ctctttattc acagttacta ttatggcatt cttaataagt
    18901 atatccatca ttcttatttc cccccgcatt atttagtaat ttttctttta atatattgac
    18961 ctgttggatg ttctttaaca ttacaacttt gtactacatg atttcctctc aaaaatacat
    19021 cttcaacttt acatttaacc ttaaatcctt catatggagt ataatctaca ttttgttttt
    19081 gagttttata actaattgtt tcttctttat tgatatttaa aatgactata tctgcatcac
    19141 ttcctacagc tatctcacct tttttaggat acattccaaa tatttttgca gcattcgtag
    19201 aagtaacttc cacaaactta tttacactta ttctattttc taagacccca tatgtatata
    19261 aaagtgctaa cctatgttca acaccaggtg ctccatttgg tatcttactg aaatcatcaa
    19321 ttcccaagtc tttttgcccc ttaaaattaa atgaacagtg gtctgtgcca actgtttgaa
    19381 tatctccact agacaatcct tcccaaaggt aatttatgtc ttcttttttt cttaaaggag
    19441 gagacattac atacttagca ccctcaaatt tatccttatt atataaattg tcttctaata
    19501 atagatactg tgggcatgtt tctactatca tatctatatt tttttctcta gccattttta
    19561 cagtttcaag tgactcccta caacttaagt ggactacata ggattttgaa ttagataatt
    19621 tagttatatc agcaagtctt gaaacagact ctttctcaac tatgttaggt cttgtaagtg
    19681 gatgatattt tggctctaaa ttaccatttt gtatattttc ttctatcaat acatctagta
    19741 aatccccatt ttcacaatga aatccaacta tacaacctaa atcccttgct ttctttaaaa
    19801 ccctgtatat tgttccatca tctactttca tgccatcata tgccatatac atcttaaaag
    19861 atactatccc atctgaaata agtttttcca tatgattaaa tgtatcttta tttaaacatg
    19921 taattgtcat atgaaaacca taatcacaat aacaatttcc acttgctttt ttatgatatg
    19981 cttctacacc ttgcagtagg ttttccccct cattggcttc tgcaaaatct agtattgtag
    20041 tagttcctcc agctatagct gctcttgttc ctgtttcaaa attatctgca gttgtaatag
    20101 aacctgcatt catatcaaaa tgagtatgtg tgtctattcc accaggaatt acaattttac
    20161 ctgtagcatc aataacctta tcaccattta tttctaagtt atttcctatt tcaactatct
    20221 tttcatcttc tatccttaaa tcacttatat aagtcttatc agaggtaatt atagttccac
    20281 ctcttagtat tgttcccata tatacctcct aacttttaag ctttaaagta ttttctaagt
    20341 attgtaaaac tttatttaaa attgtatttt ctaaaggtgc tatattcagc acctctagac
    20401 tatatttaaa taatttattg tgaactaaat attattttcc gtatacagat tttaatattc
    20461 catagtaacc ttctgttcct acaaataact gttcttgctc tatatactca tctattgtgt
    20521 gagcaagatt ttccttagaa ggaccaaatc ctatagtttt tattccagct tcacctgcat
    20581 agtgacttcc attcgtacag aatgagtatt gagttatttc tgaatctatt ccagcttctt
    20641 ttaatccctt atatgctgct tgaacaaatt catcttcttc gtcatataac caacctggga
    20701 agaatctttc actttctata gtatttcctg tatagcaatc agctttttca ac
//
LOCUS       DAEOTL010000072        20578 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.072, whole genome shotgun sequence.
ACCESSION   DAEOTL010000072 DAEOTL010000000
VERSION     DAEOTL010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20578
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.072"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            444..1514
                     /locus_tag="KRH82_002935"
     CDS             444..1514
                     /locus_tag="KRH82_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656202.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1498..2367
                     /locus_tag="KRH82_002936"
     CDS             1498..2367
                     /locus_tag="KRH82_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBG8656203.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2411..3271
                     /locus_tag="KRH82_002937"
     CDS             2411..3271
                     /locus_tag="KRH82_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBG8656204.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3302..4606
                     /locus_tag="KRH82_002938"
     CDS             3302..4606
                     /locus_tag="KRH82_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8656205.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4669..5931
                     /locus_tag="KRH82_002939"
     CDS             4669..5931
                     /locus_tag="KRH82_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBG8656206.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKDGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            6118..8088
                     /gene="uvrB"
                     /locus_tag="KRH82_002940"
     CDS             6118..8088
                     /gene="uvrB"
                     /locus_tag="KRH82_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBG8656207.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8107..10932
                     /gene="uvrA"
                     /locus_tag="KRH82_002941"
     CDS             8107..10932
                     /gene="uvrA"
                     /locus_tag="KRH82_002941"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBG8656208.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11191..13008
                     /gene="uvrC"
                     /locus_tag="KRH82_002942"
     CDS             11191..13008
                     /gene="uvrC"
                     /locus_tag="KRH82_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBG8656209.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13008..13937
                     /locus_tag="KRH82_002943"
     CDS             13008..13937
                     /locus_tag="KRH82_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBG8656210.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14149..15945
                     /locus_tag="KRH82_002944"
     CDS             14149..15945
                     /locus_tag="KRH82_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBG8656211.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16085..17866)
                     /locus_tag="KRH82_002945"
     CDS             complement(16085..17866)
                     /locus_tag="KRH82_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBG8656212.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(17889..19775)
                     /locus_tag="KRH82_002946"
     CDS             complement(17889..19775)
                     /locus_tag="KRH82_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBG8656213.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19792..20289)
                     /locus_tag="KRH82_002947"
     CDS             complement(19792..20289)
                     /locus_tag="KRH82_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBG8656214.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
BASE COUNT         7976 a         2728 c         3509 g         6365 t
ORIGIN      
        1 ggtaaattta taaaaattaa aaaagtttta ttttttatgt ttaaaccttg taaatttggg
       61 acataatata attgtaaaac ttaatatagc aaaaataaat tactcaatct cccccactta
      121 aagacctcta tcccccatag aggtcttttt tactttcaaa tcaaattata taaaaaataa
      181 atagttttat atgactcttc ataaattaaa attacattgt gatagcaaac catgaatatg
      241 aaaaatatag aaaattatag ctaacataag ctgtatatca tcttaacctc agtatattta
      301 acaaaaaatg tttataattt aacctttatt ttaataagtt taccatatat tcactttgtc
      361 ttaatatatc ctttacaaat taagagtatt attaatctat aagtaaatcg tagaattaaa
      421 ttaaatattt tgggaggata aaaatggcag atataagact agaaaatgta acaaaatctt
      481 ataataaaaa aaatacagtt atagaaaatt taaatcttac tatagaagat ggttctttta
      541 cagtattggt aggcccaagt ggatgtggta aatctactac gttaagaatg attgcaggtc
      601 ttgaagatat aacttcaggt aggttgaaga ttgaagaaaa tgatgttaca aaaacggatg
      661 ctagtaaaag ggatatagct atggtatttc aaaattatgc attatatcca catatgactg
      721 ttagagaaaa tatagaattt ggtcttaaaa acaaaaaagt agaaaaagaa aaaagagaaa
      781 aacttataac agaagttatt gatgtagtag gattgagaga atatttaaat gtgaaaccag
      841 gcaacttatc tggaggtcaa agacaaagag tggcacttgc tagagctatg gttaaaaatc
      901 caaaggtatt tttaatggat gaaccattgt caaatttaga tgctaaatta agaaatcaaa
      961 tgagaacaga attaatacaa ttacatcaaa aactaaagtc tacatttgtt tatgtaactc
     1021 atgaccaggt tgaggcaatg tcaatggcag ataagatagt tataatgaac aaaggaaaga
     1081 taatgcaaat aggttcccca aagaagatat atcaaaatcc taaaaattta tttgtagctc
     1141 aatttatagg gagtccttgt atgaacatac tagatataaa aaatgatatt aaatttggat
     1201 tcaggccaga aaaagcaaca ctagagagta taaacataga tgggaaaaat gatgatgtat
     1261 ttagcctatt tggaaaagtt gtgactaaag aagtgttggg aaatgaaact atatattgtt
     1321 tatctgttct taatagagag ataagagtca aaacggaaaa tgatatattt gatattggaa
     1381 gaactttaag aataagtgta ttagaaaaag atttatatta ttttgataaa aatggagaaa
     1441 gaatagaaga tgtaaaagta tgtaaaagta tgtattctaa aattaaagga gatatttatg
     1501 aaaaagcaat ttaataaagc atatttatat ataacacctg ctattatagg aactttattg
     1561 tttatagtct atccaataat taagacgata tctctaagct tcaaatctgg tagtcttctt
     1621 agttcaacct ttgaaaatgt aggcttaaac aattatacag aacttttaaa gaatccagag
     1681 tttatacaaa ctataacgaa cactgcaatt tatacttttt ttatggtgac tatatctata
     1741 tcactagcca tagtacttgc tgtttggcta aataaaaatt ctataataca caatttaacg
     1801 caaagtataa tctttacacc acatgtaatt tcactagtat ctgtagctgt attgtggctt
     1861 tggattatgg agccacaata tggcttttta aactggatac tatcgacatt acatttacca
     1921 acatcaaagt ggctttcaag tgaaagttca gctttaatgt cactaattct aataggaata
     1981 tggaagactc ttggatacaa tatcttaata gtgttatcag gtcttaaatc cataccaaac
     2041 tatatatatg aagcatctaa attagataat gcaaacaaaa taacgaattt ctttaaagtg
     2101 acattgccgc tattatcacc aacaatattt tttcttatga taacaacaac aactgcatct
     2161 tttcaagtat ttgatgagat aagtataatg acacaaggtg ggccagtggg ttcaactaac
     2221 atgttatctt attatatata tgagtctgga tttatatact atgacatagg acaagcgagt
     2281 gcagcgagta tgtttttgtt agctatagtt atgattgcta catatgctaa ctttagactc
     2341 ttatcaaaga aagttcatta tcaataaaga aaaagtagat attataaggt ttatccaaaa
     2401 ggaggagaca atggatatta tacaacctat caaaaaagac aaagttgata taaaaaaaat
     2461 agcatcaaaa tcaatagaaa tattaattct attactttta tctgcaatat ttatattccc
     2521 ttttatatgg atgctatcta catcctttaa aaatccacaa gaaatgatgc aattaccacc
     2581 cactattata ccaaatgata tagtgttaga aaattatagt acagcatggc attcaggtcc
     2641 attttttaga tatttgctaa acagtgtatt tgtaacagga agtgttttaa ttgtacaatt
     2701 tttagttatg gttccagcag catatgcatt ttctaagatt aaatttaaag gtgaaaaaat
     2761 gctatttggg cttttgcttg taggacttat gattccacca caagtaactt ttctaccagt
     2821 ctatatgatg atgagtaagt ttggatttat aaatacttat gttccactta taattccatt
     2881 tatgacatct tcatttggga tatttctgct tagacagaat tttatgcaga tttcagatga
     2941 aattattgaa gcagctaaac tagataatgc ttctgactta aaaataatgt ttagaataat
     3001 ggttcctatg gcaaaaccag cagtaataac atttatatta tttaatttta tataccattg
     3061 gaataattat ttctggccct tagtaatgac aaatacagat gcaataagaa ctttaccaat
     3121 aggagttgcg ctccttaaat cttcagaagg aattactgca tggaatgtaa taatggcagg
     3181 aaatataatt ctaattttac caataattct tgtttatata tttgcgaata aaaaagtaaa
     3241 agaagctttt atgtattcag gaataaaata aaaaattaaa gactaaattt ggaggatgaa
     3301 aatgaagctt aaaagaaaat tagcaacagg attagcaata acattattat taggttcttt
     3361 agttgggtgt tcaaattcta atgatgcaaa tgcatctaaa ggagaaaaga ctgatagcaa
     3421 tattacgaag atagatttct gggctccttt aggtggaact aatggagaaa ctgctcaaaa
     3481 aatggttgac caatttaata gtgaacataa ggatgtacaa gtaaatatgt taaaacagaa
     3541 agattactat gaaaatgcaa caaaactaca ggcagcctta acatctaaag accaaccaga
     3601 tgtaacatta ttagaaataa ctcaaacagg tacattcgca tcagcaggtg ctttagtaga
     3661 tatgagtaaa tattttgata aaacatatca agaaagattc ttttctggtc ttttaacaaa
     3721 ttcatattat gaggataagt ttgttggtat gccatttaat agaagtacac caatattata
     3781 cataaataaa gatatggcaa ctaaagcagg tcttgaccct tcaggtccaa aatcatggga
     3841 agagcttaag gattatgcta gtaaaatgac aaataaatca gaagatactt atggttttga
     3901 aacgccaata gatatttggt tctatgaagc tatggtaatg caaagtggag gagaaataac
     3961 taatggtaaa aaagtagcat ttaataatga ggcaggacaa gcaccagtta agttctggca
     4021 agatatgatg aaagctggaa taatgaaaat gcctcctgga gaagattata atgcctggga
     4081 cgtagcaaaa caagattttg taaatggtaa agtaggtatg atatttacat caacagcaga
     4141 tttagcagga cttatgcaac aaacagaagg taagtttgaa atatcaacag cattcttacc
     4201 aaaaaatcaa aaatacgcaa ctcctacagg tggagctaat ctagttatgc ttgaaggtgg
     4261 aacagataaa gaaaaagaag caagtgcaga atttatagaa tggatgacac aaacagataa
     4321 aatcgttcag tttagttcat caacaggata cttaccaaca actgaagatg caacaaactc
     4381 agaaaagtta caaacattat ataaagaaaa acctcaatat aaggttgcaa ctgaccaatt
     4441 acaatatgct gttgcacttc caatgttaaa tggatacaag gaagcaactg ataagctaat
     4501 ggatgagatt aaaaaggggc ttactgattt aaatgcaaat ccaaaagatg tagtaagcaa
     4561 aggaacttct gcaatgcaag cagtaataga taaaacaaat aaataattat atagacttgt
     4621 aagttgatta aaagtattca ataatatata aatgaagagg taatgtaaat gacaaaggtt
     4681 atagtattat cagtagattc tttatttgaa aaagacttgg aatttgtaaa aaatctacca
     4741 aactttaaat ctatactaga aaattgctcc atagtaaaaa atataaattg tgtttatccc
     4801 actctgacat atccgtgtca tactagtatg gttacaggag tatatcctaa aaaacatggt
     4861 atatatcata atgaaaaatt tgacccaaat aaagaaaata aagactggta ctggtattca
     4921 aaggacataa aagcaaaaac tattatagat gtagcaaaag aaaataatct aactacctct
     4981 agtgtattat ggcctgtaat gggagcaaat ccaaatatag attataatat tgcagaaata
     5041 tgggctccta gtagagaaga tgacccaaga gaaacttttg aacgaagttc cagtaaggtt
     5101 ataatggacg gtatttacaa tagacattgt cattatatcg attggaaatt agaacccaac
     5161 atggatttat ttggagtaaa ctgttcagta gatataataa aggaatataa accagattta
     5221 atgctaatac atttagctac attggaccat acacgacaca attatggctt atttaatgac
     5281 gaagtagata aagcattaaa aatgaatgat aaatggttag gagatattat tcaggctaca
     5341 aaggatgcag gtacatacaa agatacaaat tttataatac ttggggacca tggtcatctt
     5401 agagttgata aagttataaa tccaaatgtc ttgcttaaat caaatggatt tataaaagtt
     5461 gaaaatggag aagttaagga ttttgatgcc tatgtaaatt cttctggaat atcagctcaa
     5521 ataatagtaa ataacttaga taggttaaca gaattaagag aactgcttga agaatttaaa
     5581 gaagaattat tcatagagaa tatttttacc aaagaggaag catctaacct tggtcttgaa
     5641 ggtgattttg aaatggtaat tgaaggtctt gaaggaattt catttggaaa tgatttcgaa
     5701 ggaagtatta taaaagattc agatataaaa gattacaagt ttgctgttgc gacacatggt
     5761 catttaccta ctaaaggtaa tagacctcca tttatagctt ttggaccaaa tattaaagat
     5821 ggtgtggtta tagaagaagg agacctgaga gcacatgcag caactatatt aaaaatgttt
     5881 aatttaaaat tagatggagt tgaaaaagaa gcatttgatt ttattatgta agttgaataa
     5941 agtatttatt ttccatgaat tatagacttc tattgcaaag atagaagtct ttttttatgt
     6001 tttagattta agtaaaattt aaatgggtaa aatatttaaa ataacttaaa caattttata
     6061 aaggtatgat ataataatac atgtcaggaa ctaatgttcg aaaaaaggag tgatactatg
     6121 gattttaaaa taaaatcaga cttcaaacct acaggtgacc aaccagaagc tattaaatca
     6181 atagtggatt ctataaatag aaatgagaaa ttttcgacat tattaggtgt aacgggttca
     6241 ggaaaaacat tcacaatggc aaatatcatt caacaagtta agaaacctac cctaataatg
     6301 gctcataata aaactctagc agcacaactt tacagtgagt ttaaagaatt tttcccagac
     6361 aatgcagttg aatactttgt aagttactat gattattatc aaccagaagc atatgtagct
     6421 cacagtgaca cttatataga aaaagatgca agcataaatg atgaaataga taaacttcga
     6481 cattctgcta cagcatctat tttagagaga agagatacta taataatatc atctgtatct
     6541 tgtatatatg gacttggtga cccaaaagac tataaagaac ttatgttatc tataagacca
     6601 ggtatgcaaa gagacagaga tgatgtaata aaaaggttaa tagagataca atacgaaaga
     6661 aatgacataa actttacacg aggtaccttt agagttagag gagatatact agaaatattc
     6721 ccagctagta atgatgaaaa agcaataaga atagaatttt ttggtgatga ggtagataga
     6781 ataacagaaa ttgattatgt aacagggaag attgttggta ctagaaatca tgttgttata
     6841 ttcccagcat ctcactatgt aacaacgcca gaaagaattg aaaaggcaat tgtagaaata
     6901 gaaaacgagc ttcaagaaca aattaaattt ttcaaggaaa atgataggct attagaagca
     6961 caaagaattg aacaaagaac taagtatgat atagaaatgt taaaggaaat aggattttgt
     7021 caggggatag agaactattc tagacatatt acaggaaggt cagaaggaga aagaccatat
     7081 actttaatgg atttcttccc agatgattat ttgataattg tagatgaggc acatgtcact
     7141 ataccacaag taagaggtat gtatgcagga gacaggtcta gaaaaacatc acttatagag
     7201 aatggtttta gattaccttc tgcacttgac aatagaccat taaattttca agaatttgaa
     7261 ggaaatataa atcaaatgtt gtttgtaagt gctacaccag gaccttatga aattcaacac
     7321 tcagagacaa tagcagaaca gataataaga ccaactggcc ttttagaccc aattgtagaa
     7381 gtaagaccta taaataatca aatagatgat ttggtaggag aaataactaa aactatagaa
     7441 aaaaatgaaa gagtgcttat aaccacttta actaaaaaaa tgagtgagga cttgactaac
     7501 tatcttaaag aaatagggat aaaagttaaa tatttacact cagatatagt tacattagaa
     7561 agaacagaaa taataagaga tttaagatta gggaagtttg atgtccttgt aggaataaac
     7621 ttacttagag aaggattgga tataccagaa gtttcactta tagcaatttt agatgcagac
     7681 aaagaaggtt tcttacgttc cgaaacagct ttaatacaga ctattggacg tgcagctagg
     7741 aatgaaaatg gaagagtaat tatgtatgca gacaggataa ctgactcaat gcaaaatgct
     7801 attgatgaaa caaagagaag aagagatata caaaatttat ataatgaaga gcacaatatc
     7861 attcctaaaa ctatacaaaa aaatataaga gatagtatag aagctactaa ggttgcagag
     7921 gaagaagttg tatatggaat atctgataca gatgataaag acgaaataag agctaatata
     7981 gataaattaa aatcagagat gatggaagct gctcaaaact tacaatttga aagagcagca
     8041 gaacttagag ataaagtgaa acaattagaa gaaaaattgg aaaaatagaa aggtaaaaac
     8101 aacattatgg aagataaaat tataataaga ggagcaaaag aacataattt aaaaaatata
     8161 gatttagaat taccaagaga taaatttatt gtttttacag gtttgtcagg gtctgggaag
     8221 tcttctttgg catttgatac aatatatgca gaaggacaga gaagatatgt agaaagtcta
     8281 tctgcttatg caagacaatt tttaggtcag atggaaaagc caaatgtaga atatatagag
     8341 ggtttatcac cagctatctc aattgaccag aagactacct caaaaaaccc acgttctacg
     8401 gttggaacag taacagaaat atatgattat ttgagactat tatttgcaag agtaggagat
     8461 gtgtattgcc ctacatgtgg tgaaaaaata agtcagatga ctattcaaga aatagttgat
     8521 aaaatgctag attttccaga tagaacgaaa ttacaaattc tttcaccaat tgttagagga
     8581 caaaaaggta cacataaaaa agtctttgat aatatcaaaa aagaaggatt tgtaagagtt
     8641 agagttaatg gtgaaaacta tgaagttagt gatgatataa tcttaaataa aaatcaaaaa
     8701 cataatatag aagttgtagt ggacagaata gtaattaaag atggaataga atcaagacta
     8761 gcagattcaa ttgaaactgc agttaagcta tctgatggtc ttgtaatagc ccaaataata
     8821 gatggagaag aaattctttt ttcaactaaa tttgcatgcc cagaacatgg aattggcata
     8881 gaagaattat ctccaagaat gttttcattt aatgctccct ttggtgcttg tgatgtttgt
     8941 aatggtcttg gggaaagtaa agaagttgac ccagaattag tagtaccaaa caaagattta
     9001 tcaataaaac aaggtgcagt ggcagcatgg ggttcaacag gtgttaatga tgacacttat
     9061 tacagtaaaa tgataaaaag tttagcagag cattttaatg tatctttgac aacaccgttt
     9121 aaagatttac cagatgattt tgtggaggaa ttactttatg gtaaagataa tataattgta
     9181 gagtttactt atgagtcaaa atttggagga actagaaatt ataaatcata ctttgaaggt
     9241 gtaatagtaa acttagagag aagatataga gaaactaatt cagattacat gagagataag
     9301 attgaagaat acatggcaga gagaccatgt ccaaagtgta aagggatgag acttaaaaag
     9361 gaagttttat ctgttttagt tgatggaaaa aatataatgg aagttacaaa cttatctgta
     9421 aatgaattga ttgactttat ggaaaatata aatcttacag aaaaacagag atttatagct
     9481 catgagatta taaaagagat aaaaggaaga gctatgttct taagagatgt aggtcttgat
     9541 tatttaaatt tatcaagaaa agctggaact ttatcaggag gagaagcgca acgtataaga
     9601 ttagctactc aaataggttc tgcattggtt ggagttttat atgtacttga tgagccaagt
     9661 atagggcttc accaaagaga taatgatagg cttataacta ctcttagaca tctaacagat
     9721 ttaggaaata ccttaatcgt tgtagagcat gatgaagaca caatgagaga agctgattat
     9781 gttatagaca ttggtccagg tgcaggtata catggtggtg aaatagttgc acagggtact
     9841 ttagatgaaa taattgaaaa tgagaactca ataacgggtc aatatttaag tggtaaaaaa
     9901 caaatattgc ttcctgagac tactagagaa ggaaatggaa gttttataga aatagttaaa
     9961 gcatcagaaa ataatctgaa aaatattgat gtaaagttcc cattaggtaa gtttacatgc
    10021 ataacaggtg tttcaggttc tggaaaaagt acattaataa acgatatact ttacaaaggt
    10081 gttgcaagta aagtgaatag acttaagcaa agagctggta agcataagga gataaaagga
    10141 attgaaagta tagataaagt tataaatata gaccaaagtc ctattggaag aacacctcgt
    10201 tcaaatcctg ctacttatac aggtgtattt gattttataa gagatatttt tgcatctact
    10261 aatgaagcta aagcaagagg ttataaaaaa ggtagattta gttttaatgt aaaaggtggt
    10321 agatgtgaag cttgtaaggg tgatggaata ataaaaatag aaatgcattt cttaccagat
    10381 gtatatgttc cttgtgaaat ttgtaaaggt gaaagataca atagagaaac attgcaagta
    10441 aaatacaaag ataaaactat atctgatata ttagatatga atgtggaaga agctgttgag
    10501 tttttcgaaa atataccaaa tataaaaaga aaattagaaa ctttaatgga tgtaggactt
    10561 tcatatatta aattaggaca gccttcaact caattatcag gaggagaagc acaacgtata
    10621 aaattagctg ctgaacttag taaaagacca acaggaaaga ctttgtatat attagatgaa
    10681 cctactactg gacttcatat ggcagatgta gacaagctaa tccaagtatt acaaagacta
    10741 gcagatacag gaaatacaat tatagtcata gaacataatt tagatgttat aaagacttgt
    10801 gattatgtaa tagacttagg accagaaggc ggagataagg gtggaactat agttgcaact
    10861 ggaacaccaa aagaagtatc taaagttgat ggttcttata caggtcaatt cttaaagaaa
    10921 tatttttctt aagttatata aattgtgaaa aattttagag cagatatacg ataaactgtt
    10981 ttgttataag taaattagtc aaatataagt tgtaaatagt aatacaaagt aaagtccata
    11041 ttactcttca tggttaaaat tgttttcaaa tcaattatag aagggaatat gggctttaac
    11101 ttgtctaaag cactggaaat tgtataactt tttaaaattc atattttagg gtataatttt
    11161 agtataaaat ttaatgtttt ggagggcgag atgtttgata tacaagagca tttaaaaaaa
    11221 ttaccttctg agcccggagt atatttaatg aaagacaaat acgaccatat aatatatgtg
    11281 ggaaaagcca tatctctaaa aaatagggta aggcagtatt ttcaatcttc aaaaaaccat
    11341 acatctaaag taaaatctat ggttaagaat atatataagt ttgagtatat tataacggat
    11401 tcagagttag aggcattaat acttgaatgt aatttaataa aaagatacag accaaagtat
    11461 aatgtagtgc ttagagatga taaaacttat ccatatataa aagtaactac aaatgaagat
    11521 tatccaagaa tcttaaaagt tagaagagtt cttaaagata aggcaaagta ttttgggccc
    11581 tataccaata taactgctgt gaatgatacc ttggagctta taagtagtac gtatccaata
    11641 agaagctgta aaatagatat agataaagca ataaagaata agacaagacc ttgtttaaat
    11701 ctacacataa ataaatgttt aggaccttgt acaggaaatg tttctaaaga agagtatgga
    11761 aaaatgatag aagagattat aatgtgttta tctggtaaag aagaaaaatt gatggaactt
    11821 ttaaaggaaa aaatgaatga gagttctatg aactttagat ttgaagaggc tgctgtatat
    11881 agggataaga taaagagcct tgaagagatg atacagaaac aaaaaataga tgctactgta
    11941 agtgacttaa accaagatgt ggttgcaatg gcaagagctc ataatgaagc ttgtgtccag
    12001 gtatttttta taagaaatgg taagattgta ggtagggaac attttatatt agaaggggta
    12061 atggatagtc caagagcttc tatattaagt tcatttgtaa aacaatttta taatgaacaa
    12121 gagtatatac ctaaagaatt aattatagaa gatgagatag aagatagttc tatattagaa
    12181 gaatggctgt catctaaaaa ggggcaaaaa gtaacaataa gagttcctca aaagggagag
    12241 aagaaaagct tagttgaaat ggttaggaaa aatgctgtag aatatcttga aaaattttct
    12301 gatatgaata aaagaaaata tgaaaaaagt attggagcat tggaagaatt aaagcaaata
    12361 ttaaatctag aaaagttgcc aataagaata gaggcttatg atatatcaaa tatacaaggt
    12421 gtagattcga ttggttctat ggtagtgtat acgaatgcta aaaaagataa gaaggaatat
    12481 aggagatata aaataaagac agttattgga cctaatgatt atgattctat ggctgaaatt
    12541 gtagatagaa gattaaaaca tggaaattta cctgacttga tattgttgga tggtggaaaa
    12601 ggacaagtta gtgcagtaaa aaaagtacta gaactcaatg atgtagatat acctctttgg
    12661 ggaatgtaca aagatgataa gcatagaact aaaggattga tatgcaaaga aaaagaaata
    12721 gaactagata aaacaactaa tttatataga tttattgcta gtatacaaga agaagttcat
    12781 aattatgcaa taacatatca tagaagtcta agaaataaag ctttgacaaa atctatctta
    12841 gatgatatac aaggaatagg tgaaaaaaga aagaaatcat tattaaatca ctttaaagat
    12901 gtagatgcta taaaaaaagc tactatggaa gaacttttag aagtagatgg aatgaataaa
    12961 agcattgcag ataatgttta taattttttt agaaaggaag aaaattaatg gaaactagca
    13021 ataaagtatc aataagagag ataataaaag agttgaagtt aaaagtagta tacatgcctg
    13081 atgatgtaga ttattatgtc tactctcaag atataaatag accaggatta cagtttgcag
    13141 gatattttga ttattttgca tatgaaagaa tacaaatagt tggaaagaca gaatataatt
    13201 tttttggatt aatggatagt catattcggg aagaagtact agatagattt ttctcatatg
    13261 aaataccagc gttaataatt tctagagact tggaaatcaa gccagatgta attgaaaagg
    13321 ctaaaaaata taaaagaata cttttgagca caaatagaaa taccactaga cttataaata
    13381 gactgtcaaa ctatttggat aataagttag caccacatac aacaattcac ggtgtgctag
    13441 tagatattta tggtataggt gtactgataa aaggtgaaag tagtatagga aagtcggaaa
    13501 cagcattaga actgattcaa aggggtaata gattagttgc agatgatgct gtagaaataa
    13561 gaaaattaga tgaaagtatg cttgtgggtc agtcacctga actaataaga cattttcttg
    13621 agataagagg aataggaata atagatgtta gaagtttata tggagtaggg gcaatcaaaa
    13681 attctaaaat gatagattta gtagttcatt tagaagcttg ggatgaaact aagtattatg
    13741 atagactggg actggataaa gaatatgaag aaatacttgg tgttaatgta gagaaattag
    13801 ttgtacctgt taaacctgga agaaatactg ctatgatatt agaagtagca gcaatgaatt
    13861 ttagacaaag aggaatggga tacgatgcag ctcaagaatt tactaaaaaa ttatcaaaat
    13921 taatcgatac taagtagtac tgaataatag tggactacac atcatttaat taaatattga
    13981 ttaggattat gtcctacacc ttataaatta aaatcaagtt gtatatataa tgtttattaa
    14041 taagatatat tatataagga taatttaaag tacagtgtta gattataata atactagatt
    14101 aattttatat ttgagtttca ttatataaca agaaagttgg aattttttat gggaatagaa
    14161 tattttagta aacttttaga aagtagtact gaaaaagaat tgctcttaag taaaaagtca
    14221 aataacataa gtacagcaag attaatatct tttttgatag tgatagcagg gtttgctatt
    14281 ggattttaca ataaaaatat agtaggtatt tttgttggag ttttatcaat aataatattt
    14341 atagcactct tagttattca tagtaaagta aaagaagaag aaacatattt taaaagtaag
    14401 agcgaagtat taaataagta tattaagaga tttggagatg gttggaagga atttaaaata
    14461 gatggtaaag aatacttaaa agatgaaaat tcgcaagcaa aagatttaga cttatttgga
    14521 agagcatcat tgtatcaata tatctgtgta gctaatacat cttatgggaa aaatttttta
    14581 gccaaatatt tgtggaatga aaatccagat gagaatgtaa tcttagaaag acagagagct
    14641 ataaaagaac ttttatcaaa agatgatttt tctattcata ttcaaacact cagtaatata
    14701 attggtaaag agcaaaaaaa caattcagat agtagtatag aatcgtttat agagtatgga
    14761 gaaaataaga atgtgtatat accaaaatgg atgcatattt ttacttgggg tttaccaact
    14821 gcaacaatct tatcttttat attttgtatg ttaggatttt tacctgtttt acctgttttt
    14881 ttacttttta taatccagtt agggtttagt ggttttggat atccaagact tatgcaaact
    14941 cttgctccat tattttcatt tagtagaagt atacaagtat atgaaaaaat gtttgaggtt
    15001 ttagaaaaag agacgtttga aagtgcatat ttgaaagaat tacaagataa actttctaag
    15061 ggaagtggag tttcaagagg tgttaaacaa ttaaattcaa taggaaatgc tgtaaaccta
    15121 aggtataatc agatactata tataattgcc tgtggtgttt tgatgtggaa ctatcattgt
    15181 gcagaagctt tggagcgatg gaaaggtata tatggaaatc aaattagaga ttggtttgaa
    15241 tctattggag aatttgaagc tctaataagt ttaacagttg tttctcatgt aaaggaaaat
    15301 acatgttttc cagtaataaa atatgaagat actccaagat tgaaagttga agaggtatac
    15361 cacccattaa tagcagaaaa aagtgtcata gcaaattcga tacaattaaa ttctcagact
    15421 tgtattatca caggttcaaa tatgtctgga aagacaacat ttttaagaag tatcggtgta
    15481 aacttagtgc tggcatatgc aggtgctcca gtatgcgcta agagttttga tgcgacctgt
    15541 atggctatat ttacttctat gagaatacaa gatgatgtaa gtcaaggaat atcaactttc
    15601 tatgctgaga ttcttagaat aaaatcaatg attcaatata gtttaaaaga actgccaatg
    15661 ttggttctag tagatgaaat ttttaaggga actaactctg ctgatagaat tattggagca
    15721 agtgaggcag taaagaaatt atcaaaaccc tgggttataa gtatggtgac aacacatgac
    15781 tttgagctat gtgacctttc aggtagtgga gatgttgaag ttgtaaacta tcatttctca
    15841 gagtactatg tagacgataa aattcatttt gactataaga taaaagatgg aagatgtaaa
    15901 actacaaatg caaaacaact tatgagaatg gcaggtattc tttaattaat agataggtta
    15961 attaaagaat aagtctattt agaaatataa tttaatttgt gaaattaata aggattgtct
    16021 taaattacgt aaaagtattt taagacaatc cttttttaag aataaatttt atactttgtt
    16081 atgactactt agcttcttca caagcacatt cttgtggaca ctctccatag acacaactct
    16141 tatcaaagta atgagtatga aggtatttat gagctacatc actatttggt tctccaaaga
    16201 agtctttata aatagcttgt aaatcaggat tctcatgaga tttacgaata gccttatttc
    16261 tatctatttc atataacgca tttgcacgtc tatcaactat ttcagtatta ccatggtgat
    16321 aaggttgacc agcacctcca acacatccac caggacatgc cataacttct atgatatggt
    16381 atttacattc tccacttctg accttatcca taatctttct agcgttttta agtgtattta
    16441 caatacacac attaactgta gttccatcaa catctatact tgcttcccta attcctttaa
    16501 gacctctaac attagtgaag tttacattat ctaaagtctt attagttatc ttctcatatg
    16561 aagtacgtag ggcagcttct aaaactccac cacttgctcc aaatatagat gcagcacctg
    16621 tagattttcc tagaggatta tcaaaatctt ggtcttgaag attaggtaaa tcgattgcag
    16681 cttcttttat catcttagct aactctctag tagttataga aaggtcaaca tctagtattc
    16741 cagattcact taattcttct cttgaagctt catatttttt agctacacaa ggcattacag
    16801 atacaacata aagttcttca ggattgattc ctaatatttt aggtgcatag tagtttttag
    16861 ctatagaacc aaacatacct tgaggagact tacagctaga tgctaagttt aacttgtctg
    16921 gataattgtg ctctaagaag tttacccatg caggacaaca acttgttaat ataggaagat
    16981 tttcaccttt ttggattctt tctataaatt cagtagcttc ttccattata gtaaaatctg
    17041 caccaaagtt tgtatcaaat acatgttcaa atccaagtgc ttttaaagca gctaccattt
    17101 ttcctgtaga gattgaccct ggttctaatc caaactcttc accaatagca actcttacag
    17161 caggagcaac ttgcactact atagtctttt cttttttatt taaaacatcc caaagtttag
    17221 gtacattatc tacttctgtt aatgctccag ttggacagac agatatacat tgaccacaga
    17281 atgtacactc tgtttcaacc atatcagagt taaagaatgt actaactaaa gtattaaatc
    17341 cacgattaac tccagataat gctcctactg tttgtatgtc attacataca gtctcgcatc
    17401 ttctacataa tatacactta gaatggtctt taactaaaga tttagtagaa gtatctttac
    17461 ctgcaaaaga tttagaacct tgatatctta tttttcttac tcctaaatca gcagctatag
    17521 tctgtaattc acaatctcca tttttttcac agacaaaaca atcttgtgga tggtctgata
    17581 acaataattc aacaatagtt ctacgagcat ttaatgcttt agcactatta gtctgaactt
    17641 tcataccttc ctttataact gttccacaag ctggaactaa tcctctctct gtctcaacca
    17701 tacaaacacg acaagaagca caagtgtcaa gcttatctat ttcattcata tgtaaatgac
    17761 aaaggttgtg tatttttata tttattaatt tcgcagcatc taagatagaa gttccactag
    17821 gtgctgaaac gtgtttgcca ttaatagtta aattaactaa actcattgtt attcctcctc
    17881 caaataagtt atttcttgat tatagcgtta aatgtacaat tatctataca agcaccacat
    17941 tttagacact tagaagtatc tattgtatgt tgttccttaa cagaacctgt tatacaacca
    18001 gcaggacaca ctctagaaca ttttgtacaa cccttacagt catctgttat aaagtaagaa
    18061 agtaagttct gacatttacc agcaggacat ttcttatcta caacatgagc tatatactca
    18121 tctttaaaat attgaagagt acttaaaaca gggtttggag cagctttacc aagaccacat
    18181 aatgaagcag tttgtatagt ttcagcaagg ttttctaggt catctaaatc ttgtagagta
    18241 ccattacctt ctgtaatttt agttaatatt tctaataatc ttgtagtacc tatacgacaa
    18301 ggtgtacatt taccacaaga ttcttcaaca gtaaactcaa ggaagaactt ggctatatct
    18361 accatacagt cagattcatc aagaacaagc ataccaccag agcccatcat tgaaccgata
    18421 gaacttaatg aaccaaagtc tataggagtg tctaaatgtt cagttggtat acatccacca
    18481 gatggtccac ctgtttgaac agccttaaat ttcttacctt cagggattcc cccaccaatt
    18541 tcaaatacaa tatctcttaa agtagtaccc attggaactt caacaagtcc tacattttct
    18601 acttttccac caagagcaaa gactttagta ccactagaat cttcagtacc taagttggca
    18661 aaccaatctc cacccttaag tataattgca ggtatgttag caaaagtctc aacgttattt
    18721 aagcaagtag gagatttcca tagaccactc ttagaagaac tataagtttt cattctaggt
    18781 tcaccacgtc taccttcaat tgaatgcatt agcgctgtac cttcaccaca aacgaaagca
    18841 cctgcaccat attttaattc taatttaaag ttaaatccag tgcctaagat attttcgcca
    18901 agtaaaccgt atttttcagc ttgagctatg gctactttta atctttctat agattttgga
    18961 tattctgctc ttatgtatat gtatcctgta tcagaaccta tagcgtatcc acatattgcc
    19021 atagcttcta gtacactatg agggtcacct tcaagtacag atctatccat aaatgcacct
    19081 gggtcacctt catcagcatt acatacaaca aactttttat ctgttggacc agctggattt
    19141 tttgaagcag cttcccattt agagccagta gggaaacctg caccacctct accacgaagg
    19201 ccagaagttt ttacctctgc aataacttct tgaggagtaa gagaagttaa acatttgcct
    19261 agagctaaat aaccatcatt ggcaatatat tcttctatac tatctgggtc tataagacca
    19321 caatttttta aagctatacg taactgtttt ttgtagaaag acatttcttc ttgttcttca
    19381 acttttttac ttaaagattc ttcctcatat aataattcct cgacaactgt atttctaatt
    19441 aagtggcttt gaactatctt ttcagcatca gatggctcaa cttttacgta gaaaacgtta
    19501 tcaggataaa cttttacaat aggaccttga gcacagaaac caaaacaacc tgtcaaacga
    19561 acactaactt tatcttggat tcctgatttc tttatttcat tttctaattc actaactatt
    19621 tctagactgt ttgaagatgt acatccagta tcacaacaaa caagtaattc tcttcttaat
    19681 acattttcct tagaataatt ttttcttaag ctaagattag gtttcagctc atcagctaaa
    19741 acttttaatt catcaaatga atttacttta cgcattattt attcacccct cttaacaatt
    19801 caattctaat tctctataag tatctaatat ttcgcttact tggtcaggtt tcactttacc
    19861 ataaacttta ccatttacag taacaactgg agctaaacca catgccccca aacatcttaa
    19921 accttctaaa gaaaatttaa aatcactagt agtttctcca acttttatgc caagctgttt
    19981 ttcaaaagca cttaagattt tgtcagcacc ttttacaaaa catacagttc ctagacagac
    20041 actgatttta tacttaccta caggttctgt agtaaaataa gaatagaatg taacaacccc
    20101 atataccttt gcaggagcta ctccaagttt tctagcaaca tgaagttgaa cttcttttgg
    20161 aagatatcca aatatacctt gggcttcatg tagaacttgt attaacgcac cttcctttgt
    20221 tgcaagagag tcaataaata tatctagttc gtcaaataat tgcttgttgt gtgaaataaa
    20281 atcgcacata acaaatcccc cttttctttt taaagttatt atttttcata aaataattaa
    20341 ccatgagttg accccaacat tatgtgggtg aacaaaacca aaacaataaa gaaagaataa
    20401 tatacaacaa tttctttatt tataaaaaca atgcaaaaaa gttacctatt aaaaataaaa
    20461 actatactag tctattataa tataaaataa ttcagaatag ttaaaaaaaa taaaaaaaat
    20521 gagctaaatt caataaaaaa aaaataatac atataaaaaa ctttaaaaaa taaaccaa
//
LOCUS       DAEOTL010000073        20375 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEOTL010000073 DAEOTL010000000
VERSION     DAEOTL010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20375
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.073"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            229..1290
                     /locus_tag="KRH82_002948"
     CDS             229..1290
                     /locus_tag="KRH82_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBG8656215.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTSKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            1381..2994
                     /locus_tag="KRH82_002949"
     CDS             1381..2994
                     /locus_tag="KRH82_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBG8656216.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            3269..5254
                     /locus_tag="KRH82_002950"
     CDS             3269..5254
                     /locus_tag="KRH82_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBG8656217.1"
                     /translation="MSMTYMDPRVFLILEMVLEEDTNTLEQFSNVLGVSTRTIRNYIN
                     QINRELKGGIAKIVKNEKGTYSIRIEDESKLIEIVNFNRGKLSNFINLNSPDERINYV
                     LDILTMTNNPITIDDLAEEICIGRTTLIKDLKKADRILAEYDLELKRKPNIGMILVGE
                     EMDIRLLILDRLYENYIDVLENVNQINLVKDYDIECLRDELKKLFKKEELYITEQVLR
                     DVERYIIMSVLRNLNGYKFEKIDKRFEVIRCSDEYTLGLKLKDLLEKIFNIVLNEKET
                     IFLTMPLIGRKAPSTKLALSSIKINDSVKEVVDEVTSFLLETSGIDFKEDKKLIENLE
                     YHLYFALNRMRFNIRVKNPLLQEIKERYTFPYSVAKIAAMIIEEKFDLKICDHEIGYI
                     ALHFGSYFEKNSRKVLNVNRVAVVCGTGLGTAQLIRIKIGKILGESVEVNTFSDIEAK
                     ANLDLLKYYDLVFTTVDFKTDLDVPIFRVNALFNEESIKKEIENAILLKNSINLKSIK
                     KIEKNIPFIGKLIEEDKFFILNKSTFMENLEDMLEKLVHKGIIDIEFKKKVLKREKKS
                     STALDNYIALPHSVNTNGENLYLAFGILEKPVIWDTKEIRIIILMIIPDKNVDSTDLI
                     IKSYEEVLEVGRDKKMVEELAKAKSFDEFYKIITKRR"
     gene            5259..5693
                     /locus_tag="KRH82_002951"
     CDS             5259..5693
                     /locus_tag="KRH82_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBG8656218.1"
                     /translation="MDPVIFIIASLITVYLLNIFLGYLQLKDFNKNYIELKRKGRVAI
                     GRKKGRISSGTIVLILINDDGVIVETRKMQGVTVLARVKSFEGLVGKSLEYIEKSDLT
                     VYNKLLKKAILDAVKQYITFEKNKCEDTNNLSTDEECRMEVV"
     gene            5722..6282
                     /gene="srlA"
                     /locus_tag="KRH82_002952"
     CDS             5722..6282
                     /gene="srlA"
                     /locus_tag="KRH82_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418408.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBG8656219.1"
                     /translation="MTQFFQVLASGADSFMNLFRAGGQQFVGFVTDIVPLLVALLVTM
                     NAIINFIGTDRVERLAKKCSANIFTRYLILPVLGTFVFANPMTLSLGRFLPEKFKPSY
                     FAAASFSCHTMNGLFPHINPGELFIYLGIANGITTLGFSTADLAVRYLLVGIVANFIK
                     GVVTDYTTKFVEKQQGIALNSDIKIG"
     gene            6346..6714
                     /locus_tag="KRH82_002953"
     CDS             6346..6714
                     /locus_tag="KRH82_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIB"
                     /protein_id="HBG8656220.1"
                     /translation="MAFNKVKIVKGSGGWGGPLIIEPTEKKNKVVYVTGGAKPETAVK
                     IAELTGCELIDGFSQGVKDDEIACVIINCGGTLRCGIYPQKKIPTINIMKTGKSGPLA
                     MFIKEDIYVSGVKPTNVEQL"
     gene            6739..7305
                     /locus_tag="KRH82_002954"
     CDS             6739..7305
                     /locus_tag="KRH82_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBG8656221.1"
                     /translation="MAYDTKKKISEQSQGIVAKIGIALGNVTSTLFQAGRDTIDTLIH
                     TILPFMAFVAVLIGIINQSGIGNWVANLLTPLIGNVGGLVVLSIICSFPLLSPFLGPG
                     AVIAQIVGVLVGTEIGKGNIPPSLALPALFAINSQAACDFIPVGLGLAEAEPDTVQVG
                     VPSVLYSRFLTGAPTVLLAWLASFGLYK"
     gene            7346..7711
                     /locus_tag="KRH82_002955"
     CDS             7346..7711
                     /locus_tag="KRH82_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBG8656222.1"
                     /translation="MELIYSTQINKIGDNANEFLQHNMFVTFKDNAPQELENYCYIHS
                     ENNLVKEILTDDVLSINNVDYKITSVGELVNQNLSELGHITFKFTGEKDGAIGGTLYL
                     EEKEIAPIGVGTILKIIRK"
     gene            7812..8585
                     /gene="srlD"
                     /locus_tag="KRH82_002956"
     CDS             7812..8585
                     /gene="srlD"
                     /locus_tag="KRH82_002956"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBG8656223.1"
                     /translation="MRKVALVVGGGRSLGEYLSKHLAKVGYDVAIADLNEDNAKKVAE
                     EIKTEFGCKSVGYSCNAIDERQVISTVKAIENDFDRIDLLVYNAGVAVSKKITDFGYK
                     DFKFIVDVNLNGYFLFAREVSKVMIAKGIEGRIIQINSKSGRVGSKHNSGYSAGKFAG
                     VGLTQSLALDLAEHKITVNALMLGNLLDSDMFESLIPQYAVKLGIPESEVKQVYIDKV
                     PLKRGCRFIDVANMLTFYASKEAEYCTGQSINITGGQVM"
     gene            8934..11078
                     /locus_tag="KRH82_002957"
     CDS             8934..11078
                     /locus_tag="KRH82_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8656224.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKDNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            11166..11501
                     /gene="spoIIAA"
                     /locus_tag="KRH82_002958"
     CDS             11166..11501
                     /gene="spoIIAA"
                     /locus_tag="KRH82_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBG8656225.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            11515..11943
                     /locus_tag="KRH82_002959"
     CDS             11515..11943
                     /locus_tag="KRH82_002959"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBG8656226.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            11966..12730
                     /gene="sigF"
                     /locus_tag="KRH82_002960"
     CDS             11966..12730
                     /gene="sigF"
                     /locus_tag="KRH82_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBG8656227.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            13010..13447
                     /gene="spoVAC"
                     /locus_tag="KRH82_002961"
     CDS             13010..13447
                     /gene="spoVAC"
                     /locus_tag="KRH82_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBG8656228.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            13614..14627
                     /gene="spoVAD"
                     /locus_tag="KRH82_002962"
     CDS             13614..14627
                     /gene="spoVAD"
                     /locus_tag="KRH82_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBG8656229.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            14641..15003
                     /gene="spoVAE"
                     /locus_tag="KRH82_002963"
     CDS             14641..15003
                     /gene="spoVAE"
                     /locus_tag="KRH82_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBG8656230.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            15186..16202
                     /locus_tag="KRH82_002964"
     CDS             15186..16202
                     /locus_tag="KRH82_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBG8656231.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            16577..17419
                     /locus_tag="KRH82_002965"
     CDS             16577..17419
                     /locus_tag="KRH82_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBG8656232.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            17434..17898
                     /locus_tag="KRH82_002966"
     CDS             17434..17898
                     /locus_tag="KRH82_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656233.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            17885..19057
                     /locus_tag="KRH82_002967"
     CDS             17885..19057
                     /locus_tag="KRH82_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656234.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGKVALIKAIKVLAMCGVDILYSK"
     gene            19101..20036
                     /locus_tag="KRH82_002968"
     CDS             19101..20036
                     /locus_tag="KRH82_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBG8656235.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
BASE COUNT         8027 a         2118 c         3788 g         6442 t
ORIGIN      
        1 atttatttta tatatttttt taaaaatata ttttctaata taataatagc atattattcg
       61 tatcctgtat acataaaaaa taaaaaattg tcgctttaaa gtataaaaca gattatatgt
      121 taataatgtg gtgaaattat acccatatat aaataaaata aaacaaataa atagctaatt
      181 aaggagaaaa tattttttat tttttgttta ggataaataa attttattat ggaaaaaaga
      241 aaaagcatac atcttcacaa actgaatatt tatttaatag ggggaggtga tagattgttt
      301 atcacagtgg tattattttt agtaggtttc ctattaatta ctaaaggcgc agatatcttt
      361 ataaattgta ctgtagagat aggtaaaaaa acgaatatat cagaaattat acttggagct
      421 actatagtta gttttgcaac aacattacct gagtttacag tgtctctact tgcttctatt
      481 gatggtcata ctactatgag tttaggaaat gcagttggtt ctataatatg taatacaggg
      541 ttagcattag ggttggttgt ttttataagt ccatttaatg tagataaaaa aatgtttttt
      601 tctaagtctt tactattaat agtatccgtt atagttttaa ttttattgag tttagatgga
      661 gttataacaa gaggtgattc attattactt ataataatat taatctttta tatggttaat
      721 aattatagaa gtgtcgttgg aaaatctgat actaaaaata gaaatattaa aaataacact
      781 agtaaagaca tatctactaa aaaagggaaa aattataggg gtttttccgt attagaaatt
      841 gtaaaaatac tattactttt tgctacagga ttgataatga tgataatagg ttcacaaatc
      901 cttatagaga gtggagtaat aatagctagt tttttaaata tacctcaggg tatagtaagt
      961 ttaactataa tagcacttgg aacttctctg ccagagatag tttcgtcgat tactgctata
     1021 agaaaaaatc atcatgaaat atcagtagga aatattttgg gtgcaaacat attgaatata
     1081 gtatcagtaa tagctgtatc agcaatacca aataacatac caatactatc tcaaaataga
     1141 cagttggata taccattcat gatattatta ttattaatag taataatacc aacacttaaa
     1201 tctaataaac ttagtagaat acaaggtata ttgatgttat tcacatattt tctgtacata
     1261 tcaattttgt atttcatgta tattatttaa ctatactgtt taaaatatta attgcagaat
     1321 atcctaaaaa agtatataat ggataggtta agattaattg ataacggaga ggaataatat
     1381 atgaatataa caaagtttga agatttacca ataagtgagg gaataaaaaa agctatagct
     1441 gaaatggggt ttgaagaacc atctcctata caagcacagt ctatacctgc gattttgtca
     1501 ggtaaagacg ttataggaca agctcaaact ggtacgggaa aaacagctgc ttttagtatc
     1561 cctatactag aaacaataga cccaaataat agaagtttac aagctgtagt gctttgtcca
     1621 acaagagaac tggcaataca agtatcaaca gaaataagaa agttagctaa gtattcgcac
     1681 ggaataaaga cattacctat atatggtggt cagccaatag atagacaaat aaaatctcta
     1741 aagagtggtg tgcaagttgt aataggtaca ccaggacgta caatagacca tatcaatcgt
     1801 aaaacattaa agatggataa tgtaaaaatg attatattag atgaagcaga tgaaatgcta
     1861 gatatgggat ttagagaaga tatagaaatg attttaagta agattccaga agaaagacaa
     1921 acaactttct tttcagctac tatgccaaga ggaattttgg aattaactaa gagatatcaa
     1981 aaagacccag agcatataaa agttgttaga aaagaactta cagtttcaaa tacaaagcaa
     2041 tactatatag aaactaggtc atcaaataaa ttagaagtat tatgtagatt agtagatgta
     2101 tatgacccta aactatctgt tgttttctgt aatactaaga gaaaagcaga cgaattggta
     2161 ggagatttac aagcaagagg atattttgca gatgcattac atggtgactt aaaacagact
     2221 caaagagata tagtaatgga taagtttaga aatggtacaa tagatatact tgttgctact
     2281 gatgttgcag ctagaggtat agatgttgat gatgttgaat gtgtattcaa ctatgactta
     2341 ccacaagatg aagagtatta cgttcataga attggtagaa ctggtcgtgc tggtagagaa
     2401 ggtatgtcat ttacttttgt atttggaaaa gaaatgagaa agatgaaaga tatagaaaga
     2461 tatactaaat ctaaactaat aaagcataat ataccaacaa taactgatgt tgaagagaaa
     2521 aaagtaggta ctttctttgc acaagttaaa caaactatag aagaaggtca cttaactaaa
     2581 caattacaat ggttagaagg tttctgtaat gatgaagatt atgcaatggt tgatatagct
     2641 gctgcacttg taaaactatc tctaggtgaa gaaatgaaag aagaaataat agaagaaaaa
     2701 cctagaagag agcgtggaga tagaaaaggt ggtactggag ctaaagatgg tatgattaga
     2761 ttatttatca atattggtag aaatcaaaga gtacaagcaa aagatatagt tggtgccata
     2821 gctggagaag ttggaatacc aggtaaagta gtaggtacta tagatatata tgataagtat
     2881 acttttgttg aaatacctaa aaaagatgca aaaacagtaa ttgaaaagat gaaagatatt
     2941 aagataaaag gtaataagat taatatagaa aaagcaaata agaagaaaaa ataacgtata
     3001 gtatacaaaa ctataattag aaaatatata aaataatata ttggatattt aaaaagcctg
     3061 atgtgttttc aaaacagata gtagataatc tgtaagagtt aacagcataa ggcttttctt
     3121 gttttatatg atgttataat tttccagatt attgtgaaaa atgtatatta gttccttttt
     3181 ttcaaatctg atttgaaaaa gagaatatta attatctata tagtttagat tataataaaa
     3241 aatgtaagat aacaaagggg agaaaaagat gtcaatgact tatatggacc ctagggtttt
     3301 tttgatttta gaaatggtgt tagaagaaga cacaaatact ctagaacaat tttcaaatgt
     3361 tttgggtgtt agtactagga ctatcagaaa ctatataaac cagattaatc gagaattaaa
     3421 aggtggtatt gctaaaatag ttaaaaatga aaaaggtaca tatagtataa gaattgagga
     3481 tgaaagtaaa ttaattgaga ttgtaaattt taatagagga aagctatcaa attttataaa
     3541 tttaaattca cctgatgaaa gaataaatta tgttcttgat attttaacta tgaccaacaa
     3601 tccaattacc atagatgatt tggctgaaga gatatgtata ggaagaacaa cattaataaa
     3661 ggatttaaaa aaagcagaca gaattttagc tgaatatgat ttagaattaa aaaggaagcc
     3721 aaatataggt atgattttag ttggtgaaga aatggatata agattattaa tccttgatag
     3781 attgtatgaa aattatattg atgtcttgga aaacgttaat cagataaatt tagttaaaga
     3841 ttatgatatt gaatgtctta gagatgaatt aaaaaagtta tttaaaaaag aagaactcta
     3901 cataacagaa caggtcttga gagatgttga aagatatata atcatgtctg tcttaagaaa
     3961 tctaaatggg tacaaatttg aaaagataga taagagattt gaagtgataa gatgttcaga
     4021 tgaatatact ttaggattaa agctcaaaga tttattggaa aagatattta atatagtttt
     4081 aaatgaaaaa gaaaccatat ttttgacaat gccattaata ggtagaaaag ctcctagtac
     4141 aaaattagca cttagcagta taaagataaa tgatagcgta aaggaagttg tagatgaagt
     4201 aactagtttt ttattagaga cctcagggat tgattttaaa gaagataaaa agcttataga
     4261 aaatttggaa tatcacttgt attttgcact taatagaatg agattcaaca taagggtaaa
     4321 aaatcctctt ttacaagaaa taaaggaaag atatacattt ccatatagtg ttgcaaagat
     4381 agctgcaatg ataattgagg aaaagtttga cttgaaaata tgtgaccacg aaataggata
     4441 tatagcatta cattttggaa gttattttga aaaaaattca agaaaagttc taaatgtaaa
     4501 tagggtagct gttgtttgtg gaacaggtct tgggactgca caacttatta gaataaagat
     4561 aggaaaaata cttggagaaa gtgtagaagt aaatactttt tctgatatag aagctaaagc
     4621 taatttagat ttattaaagt attatgattt agtatttaca acagtagatt tcaaaacaga
     4681 cttagatgtt ccaattttta gagtaaatgc gttatttaat gaagaaagta taaagaaaga
     4741 gatagaaaat gcaatacttt tgaaaaatag tataaatctt aagtctataa aaaagattga
     4801 aaaaaatatc ccttttatag gtaaattaat tgaagaggat aagttcttta tattgaataa
     4861 gagtacgttt atggaaaatt tagaagatat gttagaaaaa ttagttcata aaggaattat
     4921 tgatatagag ttcaaaaaaa aggtattaaa aagagaaaag aaatcttcaa cagcattaga
     4981 taattatata gcattgcctc actcagttaa tactaatggg gaaaatcttt atctggcatt
     5041 tggaatatta gaaaaaccag tgatttggga tacaaaggaa attagaataa taatattgat
     5101 gataattcca gataagaatg tagatagtac agacctgata ataaaaagtt atgaagaagt
     5161 acttgaagta gggagagata aaaagatggt agaagaactt gctaaggcaa aatcatttga
     5221 tgaattttat aaaataatta ccaagaggag gtaataatat ggacccagta atttttatta
     5281 tagcatcact tattacagtg tatttattaa atatttttct tggatactta cagcttaaag
     5341 attttaataa aaattatatt gaactaaaaa gaaaaggaag agtggcaatt ggcagaaaaa
     5401 aaggaagaat ttcatcgggt acaattgtgt tgatacttat aaatgatgat ggtgtgattg
     5461 tagagactag aaaaatgcaa ggtgttacag tattggcaag agtaaagtca tttgaaggtt
     5521 tggtaggaaa gagcttagag tatatagaaa aatcagattt aactgtttac aataaactac
     5581 ttaaaaaagc aatactagat gcagtcaaac agtacataac atttgagaaa aataaatgtg
     5641 aagatacaaa taatctgagt actgatgaag agtgtaggat ggaagtagtt taaaaaaata
     5701 tatttataag gaggagttaa tatgacgcaa ttttttcaag tattagcaag tggtgcagat
     5761 agttttatga atttatttag ggcaggtggg caacaatttg taggttttgt aacagatata
     5821 gtaccacttt tagtagcatt attagttaca atgaatgcaa ttatcaactt tattggtaca
     5881 gatagagtcg agagacttgc aaaaaaatgt tctgcaaata tatttactag atatttgata
     5941 ttaccagtcc ttggtacatt tgtatttgca aacccaatga cactatcatt aggaagattc
     6001 ttgccagaaa agtttaaacc tagttacttt gcagcagcaa gcttttcatg ccatacaatg
     6061 aatggattat tcccacatat caatccaggt gaactattta tatatctagg aattgcaaat
     6121 ggtataacaa ctttgggatt ctcaacagca gatttagcag ttagatattt gttagtgggt
     6181 atagttgcaa actttattaa aggtgtagtt actgactata caacaaaatt tgtagagaaa
     6241 caacaaggaa tagcattaaa ttcagatata aagattggat aattacttta aggtataaat
     6301 aaatttttca aataaaaaga tagtgtatag aggaggataa attatatggc atttaacaaa
     6361 gttaaaatag taaaaggttc tggaggatgg ggtggaccat tgataataga accaacagaa
     6421 aagaagaata aggtagtata tgtgactggg ggagcaaagc cagaaactgc agtaaaaata
     6481 gctgaactta caggatgtga gttaatagat ggattttcac agggtgttaa agatgatgaa
     6541 atcgcatgtg taataataaa ttgtggtgga acattgagat gtggtatata tcctcaaaag
     6601 aaaataccga ctataaatat aatgaaaaca ggaaaaagtg gaccattagc aatgtttata
     6661 aaagaagata tatatgtttc aggggtaaaa ccaacaaatg tagagcagtt ataattgagg
     6721 tagtaggagg gaagaaatat ggcttatgat actaaaaaga agataagtga gcagagtcaa
     6781 ggaattgttg caaaaatagg tatagcacta ggaaatgtga caagtactct ttttcaagct
     6841 ggtagggata ctatagatac attaatacat actatactgc cttttatggc tttcgttgca
     6901 gtcctaatag gtataataaa tcaatcgggt ataggaaatt gggtagccaa tttacttact
     6961 ccattaatcg gaaatgttgg aggtttagtt gtcttatcaa taatatgttc atttccgttg
     7021 ttgtctccgt ttcttggacc aggagctgtt atagctcaga tagtgggggt attggttggt
     7081 acagaaatag gaaaaggaaa tattccacca agtttagcat taccagcatt gtttgcaata
     7141 aactcacaag cagcttgtga ctttatacca gtaggtcttg gtcttgcaga agctgaacct
     7201 gatacagttc aagtaggagt tccgtcagtt ttatattcta gatttttaac aggtgcacca
     7261 actgttctat tagcatggtt agcaagcttt gggttatata aatagaagaa tactttataa
     7321 ataattagag agaggttcag ttgatatgga attaatatac agtactcaaa taaataaaat
     7381 aggagataat gcaaatgaat ttttacaaca taatatgttt gtaactttca aagataatgc
     7441 tcctcaagag ttagaaaatt actgttatat acattctgaa aataatttag taaaagaaat
     7501 acttacggat gatgtgctat caataaataa tgttgattac aaaattactt ctgttggtga
     7561 gttagtaaac caaaatcttt cagaattagg tcatataaca tttaagttta caggtgaaaa
     7621 agatggagca attggaggaa ccttatatct tgaagaaaaa gaaatagcac ctattggcgt
     7681 aggtactata ctaaaaataa ttagaaaata aaatttaaaa cgaatctaat catattataa
     7741 gtaaattata gataaaagtc aatttaacta atcaagttaa cttttaatgt gataaaaaag
     7801 gggaaatgaa aatgagaaaa gtggctttag tcgttggagg aggaagaagt ttaggtgaat
     7861 atttatctaa acatttagct aaagtaggtt atgatgttgc tattgcagat ttaaatgaag
     7921 acaacgcaaa aaaagtagct gaagaaataa aaactgaatt tggttgtaaa tctgtaggat
     7981 atagttgtaa tgccatagat gaaagacagg ttataagtac tgtcaaagct attgaaaatg
     8041 attttgatag aatagattta ttagtgtaca atgcaggagt ggctgtaagt aaaaaaataa
     8101 ctgattttgg atacaaagat tttaaattta ttgtagacgt aaatttaaat gggtactttc
     8161 tatttgcaag agaagtatct aaagtcatga tagcaaaagg tattgagggt agaataatac
     8221 agataaattc aaaatcaggt agagtgggaa gcaagcataa ttcaggatat tcagcaggta
     8281 aatttgctgg agtaggactt actcaaagtt tagcgctaga tttggcagaa cataagataa
     8341 ctgtaaatgc actgatgctc ggtaatttac ttgattctga tatgtttgaa agtttaattc
     8401 ctcaatatgc agtaaaattg ggaatacctg aatcagaagt caagcaagtt tatatagata
     8461 aagtaccttt aaaaagaggg tgtagattta tagatgttgc aaatatgctt acattttatg
     8521 cttcaaagga agctgaatac tgcactggtc aatctataaa tattactggt ggacaagtta
     8581 tgtaaggttt ttatggagtg tctcaagatg aactctttag ttcatgaggc acttttttgt
     8641 ataaaattaa atatattttc agcatttaaa caatgaaaaa gaggtttatc tttattttga
     8701 gatagcctca tttttgtaat taaaaaacat agtgtttaag taaacatata agattgttag
     8761 ttttttaaaa gagaattttt taataatatt atatttatga agtattttta aacttaattt
     8821 gataaaatat agctatgttt tatatactgt agttttgaac atagaaagtt taataaatta
     8881 tagtatatat gttaattttt aataaggtaa gaaagtagaa agaaggatat tttatggata
     8941 taataaaaaa attaagtcat gggtgtacat tagattgtca tgactgttgt aaattcaatg
     9001 tttatactaa aggaaataat gtagtaaaaa ttgaaggaga taaaaatcat ccttatacaa
     9061 aaggttttat atgcaaaaaa gggatggccc atttagatag attaaatcat aaagatagaa
     9121 taaagactcc tatgcttaaa gttgatggag tatggaaaga gatttctttt gataaagcta
     9181 tagaaataat ggcagaaaag cttacatact ataaagaaaa gtatacatca aagtctgtca
     9241 tgcattatga ccaatatgga agtgggtctg tgctaaaata cataggagat atatttttta
     9301 atttttatgg aggtgttagc agacataagg ggggtccctg ttggagtgca gggatgcatg
     9361 ctcaaaaata tgattttgga gtagctaaga gtcatgctat agaagatatg ttaaatagta
     9421 aaagtatatt tgtttgggga aaaaatccag catatactac aattcatact atgcaaataa
     9481 ttaaaaaagc taaagaaaaa gggataaaga tagtagtgat tgaccccata tatacaaaaa
     9541 cagctcaaat agcagataag tatgtacaag taaatcctgg aacagatgga gctttagcta
     9601 tagctatggc aaaaattata gtagaagata aattatatga tgaagaatat ataaactcgt
     9661 atgttattgg ttttgaagaa tataaaaaat atttatcttc attggaatta agttttttaa
     9721 ttgatgaatg tggtgttaaa gagaatgata taagagagtt agtggattta tatactaaca
     9781 aatattcaag tataaatgtt ggatatgggc ttcaaaaata taaaaatggt ggaaacacaa
     9841 taagagcaat agatgcttta ggtgctataa ctggtcaaat aggatttagt ggtggagggg
     9901 taaactatgc taataaagtt tatccgagtg ttataaattc tgacccttac aatagccaat
     9961 catatggtga agatagggag ttttatgtaa gtaatatcag taaatttata gaagaatctt
    10021 taaaaaatac atcaaataaa gtaaattatg catcagatga acttgatatg acatcaaata
    10081 aagtaaatta tgtatcagat gaacttgata taacatcaaa taaaacagat tatatatcaa
    10141 atgaattgta taatttatct aataagtcaa tcaaagataa tattcctata aagatggctg
    10201 tgataactaa aagtaatatg ctgaatcaac tgccagattt agtagaattg gagagggtgt
    10261 tttcaaaaat tgaatttaaa gtatgttttg atatgtttat aactgataca gctactttat
    10321 gtgacatgtt tataccatgt acaaatacac tagagagtga agatataatt tatagttcaa
    10381 tgaccaatcc atatataacc tataatgaaa gagctgtaaa gccagcacat aaattgatgg
    10441 atgaatatta cttctttatg gagctagcta aaaagatggg attaaatgat tatccttttg
    10501 tagaaaagag aacttattta gaaaaagtga ttgaaccact taagcgtttt gacaaaaatc
    10561 tggatataga aaaacttaaa aacaattact ttactataca taaccctgtt gcttgggaag
    10621 ataagaagtt tgagactcca tctggaaaat acgagcttta ttcagaaagt ataaaaaact
    10681 tgggaataag tccaacacct gtatatataa gcaataaata taaagaaata gaagataaaa
    10741 atatttcttt tagattatta actaatcatc atgcagatac tttatttagt cagcatttta
    10801 tggacaaaaa atctatagct caagcatata taaatcggag aatggctaaa aaagtaggta
    10861 ttgaggacaa agatattgtg atattgaggt caaaaaaagc aaaaataaat gtacaaataa
    10921 atatagatga tggagtaggt aattatatag taaaaatgta tgttggttgg tggaagaaac
    10981 atggaaatcc taatagttta acagacactg gtatatcaga ttttgggggt caggtaacat
    11041 ataatgaaag tatggtagaa ataatacgac aaaactagtt aaatttcatt gaaggaataa
    11101 aaatataatt atagaattga ttaaaagtta ctatttttac aaaactattg aaggagggat
    11161 ttttgatggt aaattattcc ttagaacata agaatctata catagaattt atgtgctcag
    11221 aactagacca ccatgtagcc aatgaaataa gggaagaaat agataactta ttaagtgtaa
    11281 atcaagtaaa aaatgttgta tttaattttg aaaatattaa ttttatggat tcttcaggta
    11341 taggcgtcat cataggtaga tataaaaaga tttctaatga agggggacga gtttcagtaa
    11401 ttaatataag ttcacgagtt aagaagattt ttgatttatc tgggttaaat aaaattattg
    11461 gcatttatga tacgtatgaa gaagctctaa gttctttgta gggaggagta tgtgatgaat
    11521 aatattatgg aagttaaatt ttcggcaata tctgaaaatg aaagtttagc aagagttata
    11581 gtagcatcct ttgcagctaa gttagaccca acagtagatg agttagtaga tataaaaact
    11641 gctgtctctg aggctgttac gaatgctata atacatggat atgaagaaga cagttctaag
    11701 tttgttttct taagatgtga gatagaagga aatactataa agattatagt tgaagatgaa
    11761 gggtatggaa tagaaaatgt ggagaaggca atggaaccac tttatacatc aaaaccagaa
    11821 cttgatagat caggaatggg attcacagta atgaaaagct ttatggacga tgtagaggta
    11881 agttctgtaa aagataatgg gactagaatt gaaatgacta aaaaaataaa tgtgcctaaa
    11941 taaagtccaa aagtgaggtt ttattatgga agtaactgtt gccagagaag aaaaaaaacc
    12001 tcttcttagt catgaagaga ctctagaact tattgaaaaa gttcaaaatg gagatgaaga
    12061 ggcaaaagaa atattaatat caagcaattt aggtctagtt aggagcgttg tatctagatt
    12121 tttaaatata ggatatgata gagaagattt atttcagtta ggttctatag gcttaataaa
    12181 atcaatatat aaatttgacc caaaatttaa tgtaaaattc tctacttatg cagtaccaat
    12241 gattttaggt gaaataaaga gatacttaag agatgatggt atgataaaag tatcaaggtc
    12301 gttaaagcaa atagctgtaa aggcaaagat ggaaagtgaa gctttaacta aaaaattagg
    12361 tagagagccg agtatagaag aattagctaa agcaatagat gtagaaaaag aagatttagt
    12421 aatggctatg gaagctaatt tcaatgttga gtatttgcaa ggagttattc atgaagagga
    12481 aggttctcca atatgcctta ttgataaaat aagcatgaaa ggagaaagtg aagaagaaaa
    12541 agtagtggat aacatattgt taaaagacat acttggaaga ctggataaga gagagcgtca
    12601 aataatagtt ctcagatact ttgaagacat gactcaaagt gaaataggag agatgctcaa
    12661 tatatcacaa gttcaagtat ctaggataga gaagaaagta ttgtctaagt taaaagaata
    12721 tatatcgtga taatacttat gatatgtaga ataacaaaat ataataaata tattactaaa
    12781 ataaaatgta ataacttttt atgttaagtt tttaaattat taaaagatat taaaataata
    12841 aaaagcatta aaaaagtaaa aatataaaaa caaggtgtct ttatggaaaa atagattttt
    12901 tctttattag acatcttttt tattttttga ccaaacttta gatagtcaaa ataaataata
    12961 ggtttatttt tttaaaatta acaaataata ctttagagag gtgtttagta tggataaaaa
    13021 ttataaaaaa tatgtagacc aaataagccc aaaacctaca tatttaaaaa actatacact
    13081 tgcatttatt gtaggtggaa ttatttgtat gatagggcaa gcaataaatg atttgtatat
    13141 gaaagttgga ggtcttgata aactaggtgc tagttctgca acatcaataa cattaatatt
    13201 tataggggca tttttaactg gattaggagt ctacgaccta ataggaaaaa gagctggagc
    13261 tggttctata attccaataa caggttttgc taactcaata gtatctccag caatggagta
    13321 taaaagagaa ggctatgtat taggtgtagg tgcaaactta tttaaaattg caggaccagt
    13381 tttagtttat gggataggtt cttctatttt atgtggaatt atttattata tttttaagat
    13441 gttttagatg atttttattt aatttaaatt ttattaatta tgaagaaggt ataaaatctg
    13501 aaaatagcta ctaaagtaac taattgaaaa ataattgtgc agatttaatt aaaattttta
    13561 attaatatta aaaatttgaa tagtaaaatg caaaattaaa aaggtgtgaa aatatgaaaa
    13621 ataaaagaat tggaaaaaga acagtcaagt tagaaaataa accaaccata atatcaactg
    13681 gaactatagt aggtcctaag gaaggtgaag gaccactaaa ggactatttt gatatgatta
    13741 tgactgacga tttatatggt gaaaagactt gggaattagc tgaaagtaaa atggtagaga
    13801 ctgcatctca acaagctatc caaaaggcag gtaaaaaatt gtcagatgta aattatatgc
    13861 taggtggcga tttaataaat caaatagttc cagcatcatt tgcagcaaga gaactggcta
    13921 ttccattttt aggtatatat ggagcttgtt ctacaatggc agaaggtctt tgtataggtt
    13981 ctatgcttat agatggtggt tttgctgatt tagtactgtc aggtacatca agtcactatt
    14041 gtacagcaga aagacaattt agattcccac ttgaacttgg aaatcaaaaa ccaatgacag
    14101 cccagtggac agttacagga gcaggaagtg tattattagc tcctaatgga gacggtccaa
    14161 aagtaaagta tgttactgtt ggtaaagtaa tagatgaggg tattgatgat ggtaataata
    14221 tgggaccagc tatggctcca gcagcaatag atactatcta ctcttacttt gaagatacta
    14281 atgatgaccc aaatagcttt gatataattg ctactggaga tttaggtact cttggaaaac
    14341 agatagcaga agactttcta aaagaaaaag gtgtagatat atcaaaagtt tatactgact
    14401 gtggtataga gatgtttaac cttaaagaac aagatgtcca ctgtggtgga agtggatgtg
    14461 ggtgttcagc tacagtgttt gcaggatata tatatgataa gttgagaaaa aaagaattta
    14521 acaaagtaat gcttgtatca acaggagcac tactttcacc gacaagtaca ctacaaaagc
    14581 agacaatacc atgtgttgca catgcagtag taatagtaaa tgagtaggaa gtgatataat
    14641 atgttaatgg actatgtaag agtatttatt gtaggtggaa ttatatgttt aatagcccaa
    14701 gtaatgatgg attatttcaa aatgcaaact ccatatgtta tggtaacgta tgtaacaact
    14761 ggtgtagttt taacttttct aggactttat gagccattag ttaagtttgc agcagcaggt
    14821 gcaacagttc ctataatagg atttggatat tcacttgcta caggagtaat aaaatcaatt
    14881 caaagtgatg gttttttagg tattttttta ggaggtacaa ctgctacagc tggtggaata
    14941 gcagcagcta tattctttgg atatattatg tcagtagtat ttactccaaa agcaaaacca
    15001 taaatcttta ttaaaagaat aataagtttt tgaaataata actttttata aagcaggtgg
    15061 atatctttta gattccacct gttttttata taaagaagcg tttacataat tgaagttgac
    15121 aattatttac aacatagtgt agtattatat tatcaaaata aaatgaagtg aagtagggga
    15181 taaagatggt aactattaaa gatattgcaa ggaatctagg tatcagttat tcaactgttt
    15241 ctaggtgctt aaacaataat cctaatgtat ctgaaaaaac aaaaaagaaa gtggtagaag
    15301 aggcaaatag actagggttc cattttaatg taaatgcaag aaatttagca aaaaaagaaa
    15361 ctaacaggat aggggtaatc ttttcaaata attttaatca tcaagatact agaaagtttt
    15421 ttagtgatat aatggatagt tctataaatt ctattgagac taataaatac gattttataa
    15481 tacagcctaa taataacatt agtggtgata gtaatgtata taaaatggta aatggacaaa
    15541 tggttgacgg attagtaatt gtgtctcaat caataaaaaa agaagagtat gattttttaa
    15601 aagacaataa ttttccacat gtatttatat attttaaacc atcttttata ggagaagtag
    15661 ataatttctt ttgggacgat aacgtgtatg gaggttatat agctaccaag catttaattg
    15721 accatggtca taaagatata ataacagtaa cttcagatga taagagttca aaaatgcatg
    15781 aagatagaac caagggatat ttgaatgcta tggaagaagc aaatttaaag acagaagtca
    15841 ttaaatctaa aatggatttt gaatctcaag ttgaattttt agaaaaatac attgataaaa
    15901 taaaaaaagc ttcagctata tttgtacaac aagatgtacc agcgatttct ataatacaag
    15961 agttaaaaac tacttatggt ataaatgtac cagaagatat ttccataata gggtataata
    16021 atattgaatt aatatcatat tttaggtcgc atttatcaac aatagatgac ccaagagagc
    16081 aagttataaa aaatggagta gatagtttag taaatataat aaataaaaag agtacagaac
    16141 acattccaag aaaattatat ccaaggttaa taatacgaaa tagcgttaaa agaataaagt
    16201 agtaagcttt taagtatcaa acgtttatta aaaatattat agattatgtg aagtttttta
    16261 acaaataata taaataaaaa ttaaaaggag taggtgtata taagtacatt gtactccttt
    16321 atttattgag atagttttta taatatgaat gaataatttt attcaattat ttgaaaatcc
    16381 gttattttaa caatataaat taataaatta tttgtatttt atatcatgaa tctataatat
    16441 ttttttgatt cataactaaa agtatataaa aatgatgaat aaatatatat tatacattat
    16501 caatgatagg ttatataata aaatcactaa caattatatt ataagaaaat tataaaaatt
    16561 acaaggaggt atagaaatga aagaaaaagc agggattaga aatgccataa tagcagcctt
    16621 tataatcaca atattggcag aattaattgg acctatttca tttaaagtta tgggaattaa
    16681 tgtaacttta cttagtatac tatgggctat attcatagga atggctgttt ctcctcattt
    16741 attagggaga gttataccag ccttaaaaaa gtttataggg gataatgaaa taaatgtatc
    16801 tccatattta ttatctttga cactatatcc attagggata atgtttggaa ttaatgcagg
    16861 gcctaaagtt ggtatattac ttcaagcagg accagcactt ttattacaag aatttggtca
    16921 tatgggtaca atgttgatag cattacctgt tggagtagca ttaggtcttg gaagaagtgc
    16981 attaggtggt actttttcat tatgtcgtga cacagcacta ggaattattg gagataagta
    17041 tggattaaac tcaccagaag gtataggaac actaggaact tacataagtg gtagtatatt
    17101 tggaacatta ttattttcat ttttagcacc agtgggtgta cttttaggat ttcatccata
    17161 tgctttagca atggcatcag gaatgggtag tggttcaatg atgggagctg caacagcatc
    17221 attaatgaat acagttccac aaatgtcaga gcagatttta gcatattcag ctactagtgg
    17281 attgattaca gctgttactg gaatatatat agaattattc ttatctttac cagtagccaa
    17341 ctactattat agcaaagtag ctccagttat tgaaagattt agaggaagaa aaacaagaag
    17401 aacaagtaat aaattgtaaa ggaggatata tatatggaaa aaacttttaa gactattatg
    17461 gagcagataa aaatagtatt gtttatatat attattattt gctttggaca aatgatagca
    17521 cttaagactc aggctcaaga tttgttgatt ggaagtgtat ctggattttt gttggtgata
    17581 attgctatta taataaagaa ttttgttaaa aaacctaatt taccaggttt tgcatgggct
    17641 acattagttg catttgtttt atcgcttcca atatctccag tgggggatat catagcaaca
    17701 aatgtaggga aaatcaattt tatgtctaca gtaacaccat tattagcttt tgcaggaatc
    17761 tctgtaggta accaattaga tatattaaag actttgagtt ggaagttagt agttatatca
    17821 tttatagtta tgacatctac ttactttggt tctgctttta tatctcaaac agttttaaga
    17881 ttaaatggaa tgctttaagg aggtagtaaa tatgaatgaa ttaaaagcaa aaattaaaga
    17941 ggaaataaag ttattatctg aagagaaaaa gacatcattt gaaaaagttt ctgactattt
    18001 attttcaaat ccagaattag catttgagga gtataagtca caaaaagcat tatgtgattt
    18061 gttagaagaa aatgaattta atgtaactaa aggtgtagga ggattagaaa catcttttga
    18121 agctgtgtat tcaaatggaa ctaatgggaa aacagttgct tttttagctg aatatgatgc
    18181 acttccagga atgggacatg catgtgggca caatatcata gggacaagtt ctgttggtgc
    18241 aggtatcata ttaaaagaaa tcatgaaaaa acataatata gaagggactg taaaggtttt
    18301 tggaacacct gcagaagaaa gagtaggtgg aaaaataact atgattaaag aaggtgtatt
    18361 taataatgta gatgctgcat taattttaca tccaagtgat gcttcaatgc ctgatgatat
    18421 atcatttgct caagttaatt taaaatttga ttttactggt aaggcatcac atgctgctgc
    18481 ttttccttgg gaagggaaaa gtgccttaag tggagtaata gcactattta acagtgtaaa
    18541 tagcatgaga ttacatctta aagattatgc aagagtacat ggaattataa ctgatggagg
    18601 tagcatacat aatataattc ctgaaaaatc tacagctata tttaatgtaa gagctttaag
    18661 catagaatat ttaaatgaga tttgtgaaat gcttaaaaat tgtgctaaag gagctgcaat
    18721 ttctactgga actaatgtag aaatagttca attagatgaa atatacaaag agattaagaa
    18781 tgattctgaa ttagtgaata tagttagaca aaattttgaa gttttgggtg aagactatgt
    18841 tgaaagagat ttaagtcaag gtataggttc aactgataca ggaaatttaa ctcatgagat
    18901 acctgcaata caagcatata taaaattaaa agaaaatact gcaactcata cagatgaatt
    18961 tgctgttgca gctggtggtg aagaaggcaa agtagcactt ataaaagcaa ttaaggtgct
    19021 agcaatgtgt ggagtagata ttttgtatag taaataatat ataattttaa aatatattaa
    19081 gaaaggaaat cagattagac atgatattaa aacaagtaat agaggtttat gacattttag
    19141 ataaagcaaa tgctaatggg gaagaagtaa aaacttactt acaaggttat ggtgaagtag
    19201 atgtaactgt aaaagaattg tcttcaagta aaggctcaac agatttagta aagcttacaa
    19261 ttcctgggaa aaatggaaaa ttaaaaggtg gagatgctcc tactcttggc attttaggta
    19321 gactaggagg gattggagca agaccagaag ttataggttt tgtttcagat ggtgatggag
    19381 cattggtagc aattgcagtg gctgctaaac ttttggatat gcaacgaaaa ggagatatat
    19441 tagatggtga tgttgtaatt tcaactcata tttgcccaga tgctccaact aaagaacact
    19501 atcctactcc ttttatggat tctccaattg atatgatgac tatgaatgaa aatgaagttg
    19561 atagtagttg tgatgcaata ctttctatag atactactaa aggaaataga gtaatcaata
    19621 ctagaggatt tgcaatatcg ccaactgtta aagaaggcta catattaaaa actagtgata
    19681 accttttaga tattatgcag actgtaacag ggaaatctcc atttgtattc cctttgtcta
    19741 ttcaagatat aacaccatat ggaaataatc tgtatcactt aaatagtatt ttacaaccag
    19801 cagtagctac agatgcacca atagtaggag tagcaattac aacagagatg cctgttgctg
    19861 gatgtgctac aggtgcaact aattttagtg atttagattc agctgggaga tttgcaattg
    19921 aagttgccaa gctatttggt agaaataagt gtgatttcta tgataaagaa gagtgggaaa
    19981 tgcttattaa gagatatggc aaattaaata gatttcaaac atttggtata cagtaattag
    20041 aaaaatatta agtttatata atttgtgata taactattta agaatatata aacaattagg
    20101 aataaaagta agaataaagc acttagttaa aaactttaaa aataaaatat ttatttgttt
    20161 atataaaaaa ggaggattct ggttattggg attctctttt ttatgaatac aaataatata
    20221 ttgtaattat aaaaaaagga gcgtttcaaa gtgatttttt taatcacctt gagacaactc
    20281 cttatatttt tatttaaatt ctatttttta ttaagttgct ggagttccac caccatcagg
    20341 aggagtagta gagccaccac cattatttcc accac
//
LOCUS       DAEOTL010000074        20089 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEOTL010000074 DAEOTL010000000
VERSION     DAEOTL010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.074"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            253..2121
                     /locus_tag="KRH82_002969"
     CDS             253..2121
                     /locus_tag="KRH82_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656236.1"
                     /translation="MEKSSIKILIGLFIIGVIIILIFLNRTKTKNYLYQIFNVIINST
                     KLIFNYSWIYIFLCIIFSVFQGFFPIISLLIMQKMINAIQMKNIGQDIFLKLIFIYIV
                     LEMIDLMAVEIYNLYSTTFMKRFTRHIEILMLEKANRLTTKDFENKEIYDLINRAQSQ
                     NGATVIDYFNSWILIFQQAITIFSSIIIIISYQYWIVILIIIAPVIQFYYSQKLGHEQ
                     YEISMKRTSEERKCWYINFLMLLGNSIKETILYGLGNLFINQYGKLKEKFILQDYKIM
                     KKTFEMNFIIIIIGQLFTGVIYFHILLNGFWQKIYMGDVTTYITCITTIKNGIEVILS
                     MMSTIYSKSLYMELLFRFFDIPEKTELNKTKLKIDNIEKIELKHLYYKFTEDSGYVLK
                     DINLELKKNSPIALVGRNGSGKSTLIKIILGIYDDYEGDILINGINLHNIEKENYYNK
                     ISCVFQDYTKYEASVKENVGYGNLDQINNEDLIKESLIKSGLDINQLGSNKLNTILGY
                     WFGENQLSEGQWQKIAISRAMMKDADFYILDEPDAALDGIAENDMLLTYKKMFENKFG
                     IFVSHKTHHLNLLCENIIVLNNGQIAECGNHEELIEKEGIYHQLYSSQIISKLETN"
     gene            2150..3577
                     /gene="ccpM"
                     /locus_tag="KRH82_002970"
     CDS             2150..3577
                     /gene="ccpM"
                     /locus_tag="KRH82_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="HBG8656237.1"
                     /translation="MEQKPFIHLFQTSTGFYFYDVNTDSILNIDENVYDYLKKEQLGE
                     SSSNTLEYVEFLRKQGYLKSNKVKITEHPETEVLKYHCENRVEGIILQVTQNCNLHCD
                     YCTYSGGYINRIHTNKRMSKETAKRGIDYLISHSRDCQYVSIGFYGGEPLLEFDLIKW
                     CIEYSKANIEGKNLKYNLTTNATLITEEIIELFEENNVSIMISLDGPAEIHDKNRKFA
                     NNNVGSFSTIMKKLDMISTKYPNYFKNNVHFNSVLATDNFSCVNKFFTKEELFQNSLF
                     LSSIVSEVNAKVKTEKSQSFYEESQYALFIGYLTLLGRIKKEDSSKLLQTQISTIGDT
                     RNGKQGKQRLVMPEKWHHGGPCVPGVMRLFINVDGYFYPCEKASEASDSMNIGNLDQG
                     YDLKKVEKLLNIERINGDKCHSCWAYENCRICAVSLSVDSTQEDIAKECEYIRSSIES
                     DFQDYCVLKELGFDFETKELIENTI"
     gene            3640..4716
                     /locus_tag="KRH82_002971"
     CDS             3640..4716
                     /locus_tag="KRH82_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="HBG8656238.1"
                     /translation="MKKVLIYPFTEEMAPFVKQENLLKDIDITSIVSLKGNGILGDKY
                     KFNGKSLEVSENFDKELEKCTYILLNNFYSDESENIILENIKKAVNHGKKIIFFSNSN
                     SNIDNLKMIIPKEQQFEINSSKNMVKDFQGRIYNIDTPVIFVCSIFEGLEKFDIQLAL
                     RNKLLIDGYKVLQIGTRQVCELFDFYSFPEFMYSNNIEEQDKVLMLNNTLKKLELEKK
                     PDLIIIGIPGGILPFSSKAFGDFGITMYKVLQAVTPDCTILSIPHGKYSDEEISYFGK
                     ITKSKFNIEVDYYNIAAKSILSHPTETMGKPFYLTLGKSLVEKKIATLQNKNVFCLSN
                     KSEIDRLIELMIKEFIKYGTVASI"
     gene            4750..5040
                     /locus_tag="KRH82_002972"
     CDS             4750..5040
                     /locus_tag="KRH82_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="HBG8656239.1"
                     /translation="MVNTEVMNKLDIYTVLVNIFEKRSKINFDENCYLKNENLFESKI
                     MMPARELVLTLYDIEDYFSISIPEDVILSGRFNSFNNIYDIVKKLENSINFN"
     gene            5082..5300
                     /locus_tag="KRH82_002973"
     CDS             5082..5300
                     /locus_tag="KRH82_002973"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656240.1"
                     /translation="MSNFGKRNLYDSANGEIDPKGGCNCGALCANLCSCSCSGGTWSF
                     YHTNQVKGSKINNGQQFRSPGEIPGQKK"
     gene            complement(5504..7171)
                     /locus_tag="KRH82_002974"
     CDS             complement(5504..7171)
                     /locus_tag="KRH82_002974"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBG8656241.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNSY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(7368..8090)
                     /locus_tag="KRH82_002975"
     CDS             complement(7368..8090)
                     /locus_tag="KRH82_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656242.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            8481..9908
                     /locus_tag="KRH82_002976"
     CDS             8481..9908
                     /locus_tag="KRH82_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8656243.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            9901..10680
                     /locus_tag="KRH82_002977"
     CDS             9901..10680
                     /locus_tag="KRH82_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBG8656244.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            10943..11668
                     /locus_tag="KRH82_002978"
     CDS             10943..11668
                     /locus_tag="KRH82_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8656245.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNENKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            11798..13738
                     /gene="mngA"
                     /locus_tag="KRH82_002979"
     CDS             11798..13738
                     /gene="mngA"
                     /locus_tag="KRH82_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBG8656246.1"
                     /translation="MEFKKITNENLVFLKQKIKTKKDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIHKKIRY"
     gene            13867..16482
                     /gene="mngB"
                     /locus_tag="KRH82_002980"
     CDS             13867..16482
                     /gene="mngB"
                     /locus_tag="KRH82_002980"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBG8656247.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHHEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVNAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEIGHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNFV
                     NVECLMNQVKTILVK"
     gene            16742..17896
                     /locus_tag="KRH82_002981"
     CDS             16742..17896
                     /locus_tag="KRH82_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBG8656248.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDENNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKSYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTSTTTQIFNLITSIQQSKNM"
     gene            complement(18019..19932)
                     /locus_tag="KRH82_002982"
     CDS             complement(18019..19932)
                     /locus_tag="KRH82_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8656249.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IESVEVVNYIDNNNDISISRDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYHEM
                     DTKSLPNYIDDHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDKKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
BASE COUNT         7806 a         2266 c         3246 g         6771 t
ORIGIN      
        1 aaaaattaaa atatagtaaa atagaataat taaatttaaa ttgttgttga aatttttttg
       61 atttcatgct accattgtag tataaataat gattagaaac gtttcgagtt aattactatt
      121 tattttaaac tatgtcttaa ataaaatata tatttattgt tatataataa gcaataaatt
      181 gcttgataat atatttttat gtgaaaaaaa catcaaaaaa atacttttaa gaatttaatt
      241 tcaggtgaaa taatggagaa atcatcaatt aaaatattaa ttggtttatt tattatagga
      301 gtaattatta ttttaatctt ccttaataga actaaaacta aaaattatct ttatcaaatt
      361 tttaatgtta taataaacag tactaaatta atctttaatt atagctggat atatattttt
      421 ttatgcatta ttttttcagt atttcaaggt ttttttccaa taatatcttt gttaataatg
      481 caaaaaatga taaatgcaat tcagatgaaa aatatagggc aagatatctt tttaaaatta
      541 atttttatct atatagtctt agagatgatt gatttaatgg ctgtagaaat ttataattta
      601 tactctacga catttatgaa aaggtttacc agacatatag agattttaat gttagaaaaa
      661 gctaatagat taactacgaa ggattttgaa aataaggaaa tttatgattt aatcaataga
      721 gctcaatctc aaaatggagc tacagttatt gattacttta actcctggat tttaattttt
      781 caacaggcaa tcacaatatt ttcctcgatt attataatta tatcttatca atattggatt
      841 gtaatattaa tcataatagc cccagttata caattttatt actctcaaaa attagggcat
      901 gagcagtatg aaataagtat gaaaagaact tctgaagaaa gaaaatgttg gtatattaat
      961 tttttaatgc tattaggaaa ttcaatcaaa gaaacaattt tatatggatt aggaaattta
     1021 tttataaatc agtatggaaa attaaaagaa aaattcattc ttcaagatta taaaataatg
     1081 aaaaaaacat ttgagatgaa ttttataatt ataattattg gtcaattatt tacaggagtt
     1141 atatattttc atatacttct taatgggttt tggcagaaaa tatatatggg agatgtaact
     1201 acttacataa cctgtataac aacaataaaa aatggtatag aagtgatatt atcaatgatg
     1261 agtacaatat atagtaaatc tctatatatg gaactattat ttagattttt tgatattcct
     1321 gagaagacgg aacttaataa aacaaaactt aaaatagata atatagaaaa aatagagcta
     1381 aaacatttat attataaatt tactgaagat tcaggttatg ttctaaagga tattaatcta
     1441 gaactaaaaa agaatagtcc tattgcactt gttggtagaa acggttctgg taaatcaact
     1501 ttaatcaaaa ttatactagg aatttatgat gattatgaag gagatatctt aataaatgga
     1561 attaacctac ataatatcga aaaagaaaat tactacaata aaataagttg tgtttttcaa
     1621 gactatacca aatatgaagc tagtgtaaaa gaaaatgtag gatatggaaa cctagatcag
     1681 ataaataatg aggatttgat aaaagagtca ttgataaaat ctggactaga tattaatcaa
     1741 ttggggagta ataaattaaa taccatttta ggatattggt ttggagaaaa tcaactttca
     1801 gaaggccaat ggcagaaaat agcaatatca agagctatga tgaaagatgc tgatttttac
     1861 attttagatg aaccagatgc cgctttagat ggaatagctg aaaatgatat gcttttaact
     1921 tataaaaaaa tgtttgaaaa taaatttggt atattcgtat ctcataaaac acatcattta
     1981 aatttgttat gtgaaaatat aatagtttta aataatggac aaattgcaga atgtggaaat
     2041 catgaggaat taatcgaaaa agaaggaatt tatcatcagt tatattcaag tcaaattata
     2101 agtaaactag aaacaaatta ataattactt tgaaaaggag ttaagaatta tggaacaaaa
     2161 accttttatt catttatttc aaacatcaac tgggttctat ttttatgatg tgaatactga
     2221 ttctatatta aatatagatg aaaatgtcta tgattatcta aagaaagaac aacttggaga
     2281 gtcaagtagt aatacattag aatatgtaga atttttaaga aagcaaggat acttaaaatc
     2341 aaataaagtg aaaataacag aacatccaga aactgaagta ttaaagtatc attgtgaaaa
     2401 tagggtagaa ggaataatat tacaagtaac tcaaaattgt aacttacatt gtgattattg
     2461 tacttattct ggaggatata taaatagaat acatacaaac aaaagaatgt ctaaagagac
     2521 tgctaaaaga ggaattgatt atttaataag ccattcaaga gattgtcaat atgtgagtat
     2581 aggtttttat ggcggagagc cattactaga atttgattta attaaatggt gtattgaata
     2641 ttcaaaagcg aatatagaag gtaaaaattt gaaatacaat ttaacaacta atgcaactct
     2701 tataacagaa gaaattatag agttatttga agaaaataat gttagtatta tgattagtct
     2761 agatggtcct gctgaaatac atgataaaaa tagaaagttt gcaaataata atgtaggatc
     2821 ttttagtact ataatgaaaa aactagatat gatatctact aagtatccaa attattttaa
     2881 aaataatgta cattttaatt ctgtattagc aactgataac ttctcttgcg ttaataaatt
     2941 ctttactaaa gaagaattat ttcaaaattc attattttta tcttcaattg ttagtgaagt
     3001 aaatgctaaa gttaaaactg agaaatcaca aagtttttat gaagaaagtc agtatgcttt
     3061 attcatagga tatttaactt tacttggtag aataaaaaaa gaggatagtt ctaaattatt
     3121 acaaactcaa atctctacta ttggagatac gcgaaatggt aaacagggca aacaacgttt
     3181 agtaatgcca gaaaaatggc atcatggggg tccatgtgta ccaggagtta tgagattatt
     3241 cataaatgtt gatggttatt tttatccatg tgaaaaagca tcagaagcat cagatagtat
     3301 gaatatagga aatttagatc aaggatatga ccttaaaaaa gtagaaaaat tattgaatat
     3361 tgaaagaata aatggtgata aatgtcatag ttgttgggct tatgaaaact gcagaatttg
     3421 tgctgtttct ttaagtgttg attcaacaca agaagatata gcaaaggagt gtgaatatat
     3481 tagaagtagt atagaaagtg atttccaaga ttattgcgta ttaaaggaat tgggatttga
     3541 ttttgaaaca aaagaactta tagaaaatac catttaattt aagatagcat cttaaattat
     3601 tacattatga aactaattag aatctattgg aggattaaaa tgaaaaaagt attaatttat
     3661 ccattcacag aggaaatggc tccatttgtt aaacaagaga atttactaaa agatatagat
     3721 ataacatcaa ttgtaagttt aaaggggaat ggaatcttag gagataaata taaatttaat
     3781 ggtaagtctt tagaagtttc tgaaaatttt gataaggaat tagaaaaatg tacatatatc
     3841 ttacttaata atttttatag tgatgaaagc gaaaatatta ttttagaaaa tataaaaaaa
     3901 gctgtaaatc atggtaaaaa aataatcttt tttagtaatt caaatagtaa tattgataat
     3961 ttaaaaatga ttatacctaa agaacaacag tttgaaatta atagttcaaa aaatatggta
     4021 aaagattttc aaggaagaat atacaatatt gatacacctg ttatttttgt atgtagcata
     4081 tttgaaggct tagaaaaatt tgatattcaa ttagcattaa gaaataagtt actaattgat
     4141 ggatataagg ttcttcaaat tggaacacgt caagtttgcg aattatttga tttctactca
     4201 ttccctgagt ttatgtactc aaataatata gaagaacaag acaaggtact aatgcttaat
     4261 aatactctaa aaaaattaga attagaaaaa aaacctgacc ttataattat cggaattcca
     4321 ggtggtatac ttccattttc ttcgaaagca tttggtgatt ttggaattac aatgtacaaa
     4381 gtacttcaag cagtaactcc agactgtaca atactatcta ttccacatgg taaatatagt
     4441 gatgaagaaa tttcttattt tggtaaaatt acaaaaagta agtttaatat agaggtagat
     4501 tattacaata ttgctgcgaa atcaatatta tctcacccaa cagagactat gggaaaacca
     4561 ttttatttaa cattaggaaa atcattagtc gagaaaaaaa tagccacatt acagaataaa
     4621 aatgtatttt gtttatctaa caaatctgaa atagacagat taatagaatt aatgatcaaa
     4681 gaatttataa aatatggtac tgtagcatct atataaaata ttttacataa aggatggtga
     4741 aatactgata tggtaaacac agaagttatg aataaactag atatctatac agttttagta
     4801 aatatatttg agaaaagatc aaaaataaat tttgatgaaa attgttattt aaaaaatgaa
     4861 aatttatttg aatctaagat aatgatgcct gctcgtgaac tagtattaac attgtatgat
     4921 atagaagact atttttctat atctattcca gaggatgtaa ttttatcagg aagatttaat
     4981 tcttttaaca atatttatga tattgttaaa aaacttgaga attctattaa ttttaattaa
     5041 ttaaaatata ataatataac aaatgagagg ggaaaaatga tatgtctaat tttggaaaaa
     5101 gaaatttata tgattctgca aatggagaaa tagatcctaa aggaggatgt aattgtggtg
     5161 ctctgtgtgc aaatctatgc tcttgtagtt gttctggggg aacatggtca ttctatcaca
     5221 caaatcaagt gaaaggttct aaaataaata atggtcaaca atttagatca ccaggagaaa
     5281 tacctggaca aaaaaaataa aaagagttaa atataattag ttttagcttt atcaattaac
     5341 ataattaact ttattaaaat taatagaatc taattacaat tgtttattat atctataaaa
     5401 gcaactttaa aataccttgt tttatatatg ttaattaaaa atggtaggag ctgtcgtgct
     5461 agaaaatagt gctacagctc ctaccatttt tacataaata actttattta taatatatca
     5521 ttatactttc gtaaggtttt atttccattt tattttcaat tatatctcta gtgtaattgg
     5581 tttcaagtat tgtgtagttt aatttattca aataagtttc aggtaattta tatactacat
     5641 tatcatgagt aaaattactt ataacaagaa gattttggtt tttatactct ctttcataaa
     5701 caaatagatt tttatgattt tcatctaaca atctataagt accttctgta aaaatatcat
     5761 attgtttacg atatttgatt aatctttgat aagtataaaa gactgaacga gaatcattaa
     5821 gctcattttc tacactaata ttgtcattat taacttttaa ccacggttta tgattagaaa
     5881 accccttata aatagtatta tcccattgca taggagtacg ggcattatct ctggattttt
     5941 gttgaagtat aagcaatgcc tccttttcat caataccaga tttaatcata tgatagtatg
     6001 aattcttact ttcagcatca tcatattcat ctattttagt aaagtaggca tttgtcatac
     6061 ctatttcttc accttgatat atgtatgtag taccttgtag accaaatagt gttatggcta
     6121 acatcttagc actttcttga cgaaaaaatc tatcatctcc aaatcgagat aaagctctag
     6181 gttggtcgtg attagagtaa aatagagcat tccatccctt tccttcatac attttatatt
     6241 gaaagtcaga ttgtgctttt tttaatttat ccagagagaa catttcatta gtccattttg
     6301 cgcctccttt ataatctgtt ttcatatgat ggaagctaaa aaccatagat agttcttctc
     6361 gattttctct agtatagttg atacactctt caggtgtagt agatgacatt tcacctacag
     6421 taactatatt tttaggtttg aaaacttttt gattcatatt atgtaaatat tcgtgtatac
     6481 gaggaccatc agcgtagtga gttcttccat ctccttttgg tcctgttata gggtcatcag
     6541 gtaatccagg tgttttggag agtaggttga ctacatctaa acgaaaacca tcaatacctt
     6601 tatcagccca aaattctagt attttgtaac attcttcacg aaccttttca ttttcccaat
     6661 ttaaatcagc ttgagtttct tcaaataaat gtaaataata ttggttagtg gtttcatcat
     6721 atttccaagc agttccacta aatctggata tccagttatt aggaacagaa ccatcaggtt
     6781 tagcatcttt ccagaaataa taatcacgat atggattgtc tttgcttttt ttagattctt
     6841 taaaccattt atgttcagta gatgtatggt ttaggaccat atccatcatt atttttatgt
     6901 ctcttttatg agcttctttt aagagttttt caaagtcatt cattgtccca tattttgggt
     6961 ctatattata ataatcttct atatcatatc cattatctct ttgaggagaa acgtacatag
     7021 gagtcaacca taataaatca acacctaaag aatacagata atctaatttt tctataatac
     7081 catttatatc acctatacca tcattgttgc tatctttgaa actttttgga tatatttgat
     7141 agacagttgc ttttttccac caatttttca tacttgatac ctcctgtaat ttataagtta
     7201 attataatat gtttaaacaa attgtcaagt attaaactga tattaaagct aaaatataca
     7261 ataaataatt atttgtataa acatataatt gtatatagaa tagtgaggtt agtatgggat
     7321 aaagtgtcta aacgtaaaaa aattatgttt aattaaacat aattttttta atatctttga
     7381 gtaacatcca tgaatacaaa tgtttcaggt gtatgctttg attcagtata ttcaaaaagc
     7441 tttccatcat cagtatatac actattttta ataacaccaa cacaattata atcatttaga
     7501 ggtagcgttt ttaactcaag ctctgtagct ttttcaattt taaatatctt tctggatgaa
     7561 acaatttttg tacctagaca ctcttctata tatttataaa tagagccttg tgctatagaa
     7621 acatcaaggt ctttaactat actacataga aaatagttaa tgtcgagaat tttaggtatg
     7681 ttatcaatat atcttagtct gtgaaggtaa tatacttcac taccaacttt aaaacctgtc
     7741 tttttagata acttattatc aattaagatt ttgctgaagt ggagaacact agtagcagta
     7801 ttaacctttt tatcttctac aatcgattct acacctttga aattgtgcat atttagaaaa
     7861 aaatcattag aacaactatt ttctaacact acaacacctt tgccttttat actttgaaca
     7921 tatccttctg tgtttaattg agaaattgct ctacgtacag tgtttctgct acatgaaaac
     7981 ctttcaataa gttgaagttc agtaggcagc atcatattac ttgtatattt accatcaagt
     8041 atttcctctt tcaatacttc atatatctct gaaaatttat ttttagccat atacccctat
     8101 ccctccttaa aggtctttag taatcttatt gaactgatat gaacaaatta tatcaaatgt
     8161 gtttagacat gtatagtgaa aatagaatca tatcaaccat aaaaaggaca aaatagaatt
     8221 attttgtggg ttgtttcaaa tacatggtta aacatatttt taaaataaaa aaaatgaatt
     8281 aaaaaaatag gctagatata gcaatacact taaaaggatt tatatgttaa accaaatgat
     8341 aaaaataaaa tgaataaaaa atattgacaa tttgtttaaa caaatataat atttaaaata
     8401 taaaatgtga ataaatcgtt ttcataaaaa attaaaccga aatagaaagg ggattgtata
     8461 tgaagaggtt cttaaacaaa atgatgcaac aactgtcact tttaggaaag actatgctgg
     8521 tgccaatagc tgtaatgcca gcagcaggta tattaggatt attatttggt ccaaatatgc
     8581 tcaatgtgcc agctatatct aatatatcta atatagtatt ttcaaatgtg gactacttat
     8641 ttttattagg agcagctagt gcctactcaa agtctaaaga caagacaagt gtaatggttg
     8701 cagccgtagt tgcatatatg atatttaagt caaatttaga gttattgaat gatacattaa
     8761 atgcaggtgt atttggtggg ataattgttg gagcttgtat agcatggact tacaataaaa
     8821 catataaagt taaagttcca gcatttttaa gcttctttgc aggagaaaaa tgtgtaatta
     8881 cactatcacc agtggttgct ttaattttat catatatatt tagtttatta tggatatatc
     8941 cacaagctgc aatgaatcaa tttggttttt ggttgggagg agctggtgca ataggaatat
     9001 tcttgttttt attctgtaac cgtgcactaa taccaactgg gttacatcaa gttttaaatg
     9061 cttacatatt atttgaaatg ggtgaatata caacatcaac aggagaagtt ataagaggag
     9121 aaattcctag atttatggca ggagacccaa atgcaggatt cttctggaca ggattttaca
     9181 taattatgat gttttcaata cctgctattt cttatgctat atataaaaca gcacaagata
     9241 aaaagaagca agaagtaaaa ggtgcaatga ccgctggagc attgacttct tttatggcaa
     9301 cagtaactga accaatagaa ttttcgtttt tatttgcatc tccaaagtta tatataattc
     9361 attcttttta ttctggtcta ggtggagttg tactatattt actgggtgct cgcttgggtt
     9421 catttaatgg agcaagtata attgactatg tcttaagttt tagttatgga gataaagcgt
     9481 ggttagttat acctgtagga gttgtattct ttgtattata ttatgtaaca tttaaatata
     9541 taataataaa agataatgtg caaacaccag gacgtgaagt tgagatagag ataggtgata
     9601 aagttagtga aaaagaaaag aatttaaaac tttctcatgg taatttttca tatatggcta
     9661 aacagataat taaaaattgt ggtggttatg aaaatatagt gactcttaat aattgtatga
     9721 cgagattacg tttagaagtg aaggatgcta ctattttgaa tgatgataat attaaaaaaa
     9781 caggagccaa aggggtaatt aaattgagta atacatcagt tcaaatcatc ataggaacgg
     9841 atgttgttaa agtaaaggat gagatggaaa tgcaacttga tgagttgaga aagcaggcag
     9901 atgcataaaa tgaagaaatt agtagttagg gcagatgata taggatattc agaaggtgtt
     9961 acactaggga taatatcttc ttataagaac ggtattgtta caagtgctgg aatcatggtg
    10021 aatatgcctt tttcaagaca agctatagaa atggtaaaaa atgatgatgt atgttttggt
    10081 ttacatgtta atttagtaat aggagaacct tgttgcaaag aacatattaa gataaagaat
    10141 ttgttagatg aaggtggaaa atttgtttct agcaaaataa gaagaacgca actactgaca
    10201 ggtaaagagg tttttaatta tgaagaagta tatgaagaag tttgtgctca aattgaaact
    10261 tacaagttgt atatgagtaa attgcctgag tatattgata tacatggtat agaagaagat
    10321 gtatcaatat cagcaatgtg tgatgctgca aaagaatacg gtataccaag ttgtccctat
    10381 tatttagatt cgtgtattag catgccaagt aaatatcctc agaatgattt ttacaagtta
    10441 aataaatctt ttgttaaatt atttgaagaa aaatatataa atttagataa agatataaca
    10501 ttgatggtta ctcatccagg atttatagat tatagtctta taaaatcatc ttctcttatt
    10561 caagagagag tatatgaaca tgcaatgcta tgtgataagg aagttaaaat gtggttaaaa
    10621 agaaataata ttgaattggt tgattttaaa gatattttca agtctaataa ttatatataa
    10681 agaatagatt acctaaagtt ttaattaaaa ataagtattt gaaaaaaatg tgtattttct
    10741 aaaaaaatat tgatagagat gtatcaaaat aaaaacttga atcatctcta tcaatatagg
    10801 aagtacacat tttttatgta taataaaaag agtagtatgc attaataaat taaaaatatt
    10861 aaattataat tatattaacg aaaattttag ctaatatttt tgaattttac ttatgaataa
    10921 taaaatagat ggaggagaaa ctatggaatt ttatgaaaga gcaaaaaaat atgagtataa
    10981 atttacagat acagaagaca tgataattga atatatgaga aaaaacaaag aagaaatagt
    11041 aaaattatca atacaatctt tagcagataa attttttact gtcccaaata ccatagttag
    11101 gctatgtaaa aaaatggagt atgatggttt ctctcaacta aaaaataatt taaaagaaga
    11161 gttaaaaaat gagaataaag agccaaaaaa tggttttgaa tcagatataa aaaagacatt
    11221 agagctaata gattatgaaa aaataaataa agtagcagat ataattcaaa aatctaggag
    11281 tattatagtt tatggaatag gtcaaaacat tcctttatgt gagatattag taaaagaaat
    11341 tagaggtggg catgataata taacttacta tagtcaaaga catgaagtac ttcatgatat
    11401 aggaaaatta ggtgaacaag atatgttttt tgcacttagt ttaagtggag aaacgaaaga
    11461 agttatagaa gcagcaaaga cagcagttaa taagggttgt aaggtagtag ctctaacaca
    11521 tatatgtgaa aatcaattgc aacaaattgc agatataagt ttatattgct attcaacaat
    11581 taaacaagta aatgggtaca atatatcaga taaggttcca attatgatga ttatgagagc
    11641 aataatagaa caatactggt taagatagag atttgtgtat aaatacacaa atctttattt
    11701 tttaagaaga aattgtgtgt ataatttcaa aaaaacattt tcataattta ttttatgcta
    11761 tattcatagc attaaatgat ttaaggaggg cgtaattttg gaatttaaga aaatcacaaa
    11821 tgaaaacctt gtttttttaa aacaaaaaat aaaaacaaag aaagacgcaa taaagttctt
    11881 agcaagaaag ctatatgatg aaggcaagtt aacatcttat gaggaatatt tagaagctgt
    11941 aatgtacaga gaaactttat ctccaacagg ttttgaaaga gggcttgcaa ttcctcatgg
    12001 aaaatctaag tcagttaaag aagctgcatt tgcagctatg accttagaga caccaataga
    12061 aaattgggaa agcgtagacc caaataataa agtagagata atatttttaa tagcagtacc
    12121 agaaaatgaa ggtggaaata cacacataca aatactttct gagttagtta ctagactgtc
    12181 aaatgaagat tatatgaata tgttgttaaa ttcaaaaact aagaaagagt tatttaataa
    12241 cttagatata aaagaaaaga aagaacaaat aaaagaagag attaggattc aaaatgaatc
    12301 aaaaaaaatt atattagcaa taacagcatg ccctgcaggt atagcacata catatatgtc
    12361 agcagaagca ttaattaaag ctggtaaaga aatcggtgtg gatgtgtatg tagaaaagca
    12421 aggagctaat ggtatggtgg accctcatac accagatata ataaaaaggg cagatgcaat
    12481 aatatatgca acagatgtag cacctaaaaa tacagaaaga tttgaacatt tgccaaacat
    12541 aaaaacgtca gtagcagctc cactaaaaag agcaaaagaa ataatatacg aagctttaga
    12601 agtagcacaa aaacaaggta aaggtgatta tatagaaaaa tcatctgata tatcatattg
    12661 tgaaaaatca tcatggaaaa aagatgtaaa atcagcaata cttacaggag tatctcatat
    12721 aataccactt attgtggcag gaggtatgat acttgcattt gcagtattag catctcaagc
    12781 atttggtcta caagaactat acaaccaaga aggttcttgg ttatggcaat taagaaagct
    12841 ttctggaggt atgttaggta cattgatggt tccagtatta tcagcatata tgtcttactc
    12901 actagctgaa aaaccaggtc ttggaccagg atttgcagca ggtctagcag ctgatttaat
    12961 aggtagtgga tttcttggag gtatgttagg aggtttactt gctggttata tagtaaaatt
    13021 tttaaagaag aatataccag ccaaaggcac attagctgga ttcgtaagtt tttgggtata
    13081 tccagtagtt ggttctttgg tagtaggttt attgatgtta tttgtagtag gaaagcctgt
    13141 agcagcactt aacaatggtc ttataaattg gttaaatggg atgactggag taaatgcaat
    13201 actactaggt gcaataatag gagctatggt ttcatttgac ttaggtggac caataaataa
    13261 agcagcctat acatttgcaa taggagcaat agcaagtgga aattttatac cttatgcaat
    13321 atttgcatca gttaagatgg tttcagcttt tggagttaca atagctactg ttttaggcag
    13381 agatttattt tcagaatcag aaaaggaaat aggaaagcaa acttggatat taggattggc
    13441 tggaataact gaaggtgcaa taccatttat gatagaggac ccaatccgtg ttataccatc
    13501 attggtagct ggttcagcca taactgggtc tatagtagca ttcttcaata taggtcttca
    13561 agtgcctgga gcggggatat tctcattggc gcttttagag ggaagtatgt caggatttat
    13621 tatagcatca atatggttct ttgcggcagt acttggagct ataatatcag caatattatt
    13681 aataataact aggaaacaaa aaaatcaaag aaagatacat aaaaagatac gttattagat
    13741 atttaaatca aaggtttaat tatagtgata aaataaatat taaaaaattt tgtaaactca
    13801 gtagtatttt tattggattt ttaattagac agaaaatatt atcagataag ttttggagga
    13861 taagcaatga aaaaaaatgt acacatagtt cctcatatgc attgggatag agaatggtac
    13921 ttctcaactg aggaatctag aatattactt gtaaataata tggaagaaat aatggatatg
    13981 ttagaaaata atcataacta tccatattat gtgatggatg gtcaaactgc tatattagaa
    14041 gattatttag cagttaagcc tgaatgtaag gagagaataa aaaaattagt tcaagaagga
    14101 aggctaataa taggtccttg gtatactcaa actgatgaaa tggtagttgg tggagaatcc
    14161 atacttagaa atttactata tggaataaaa gattgtgatg aatttggaga atatatgaaa
    14221 ataggatatt taccagattc atttggtcaa agtgctcaaa tgccacaaat actaaatggg
    14281 tttgatataa aatactcaat gttttggaga ggatgttctg aaagaaaagg aactaataaa
    14341 acagagttta attggaagag tgatgatggg tcttctgttt tggttcaaat acttccatta
    14401 ggttatgcaa taggaaaata tctaccaatg aatgaagatg agctaagaac aagaatggat
    14461 aaatatttac cggttcttga taagggtgca actactgacc atataatact tccaaatgga
    14521 catgaccaga tgccaattca aaagaatata tttgaagtta tatataaatt aaaagaatgt
    14581 tatccagaga gaaaattttt cttaagtaga tatgaaaaca tatttaaaga gctagaaaaa
    14641 aatgaggata tagatacaat aaaaggggaa tttttagatg ggaaatatat gagggttcat
    14701 agaagtatat tctcaacaag aatggatata aaatcagcaa atgctagaat agaatcaaag
    14761 ataaccaaca tattggagcc actagcttct attgcatatt ctctaggatt tgaatatcat
    14821 catggattaa tagagttaat ttggaaagaa ataatgaaaa atcatgctca tgacagcatt
    14881 ggatgttgtt gttcagataa agttcaccat gaaataatga atagattttt cttagctgag
    14941 gaaaaagtag accaattaat aacattttac aaaagaagaa tagttgatgc aatgagttgt
    15001 gaaatggctt tagataagtt agtagcattt aacttaatgc cttacgatag gaatgaaata
    15061 gtgaacgccc aagttataac taaaatgaaa gcatttgaaa tatttgataa agataataat
    15121 aagttggatt ttgaagtggt acataaagaa gtaatagatg caggattaat agaccgtcaa
    15181 attgttcatt atggaaacta tgattcattt atggtatata caataaactt taaagataaa
    15241 atacctgcaa tggggtataa ggcgtatatg ataaaagaaa ttggacatat gttagaaaaa
    15301 gcttatgaag tatgtgacat ggtagataat gacttttata ctattcaagt taatgaaaac
    15361 gggacattaa agatatttga taaaaaatta aataaaactt ttgaaaatgt attattgatg
    15421 gaaaatggag gagatgaagg agatgagtat gatttttcac cacttccaaa tgagaaatta
    15481 atatttaacg ataatatagt agcaaattcc actataaaga aaaatagatt taataatgag
    15541 ataaagataa attatagatt aaaagtacca aaagatatac aagctagaaa aaataataga
    15601 gcagattcat ttattgactt tgatatagtt ataaatgttc caaatgataa agctataata
    15661 gatgtagtat tcaacataaa taaccaagca agagattgta gggttagaac ttatatacca
    15721 acaaatatag cttcaaagtt ttctgtgtct gataatcagt ttggacatat aaagagaagt
    15781 gtgtatgatg atgctatgga agtttggcaa caggaagaat ggagtgaaag accagattct
    15841 atatatccaa tgctaacatt cgttggattg tctgacaaag agcatggagt agctgttctt
    15901 acaaacagta caagagagtt tgaaatagta ggggaaaaat ttgacacaat agctataaca
    15961 ttatttagaa gtgtaggatt cctaggtaaa gaagaaatgg caagacgccc aggtcgtcca
    16021 tcaggaataa agttgcctac tccagattct caaatgatag gagatataaa aatagactta
    16081 gcaatagtta ctcatgaaaa atctacacta gaagcaaatg ttgcaaatat ggctaaagag
    16141 tatttaacaa aaatacaaac ttataataaa atgccatata atgctatgaa attgaatcaa
    16201 tcagaaatag aagtagatta ttcatatagt ttacttaagg aaactaataa ggaccttgtg
    16261 ttaagtgttg taaaaaaggc tgaaaaacaa gaggcattag tagttagatt ttacaattct
    16321 aaagaagaaa caaaatcagc taacatagta tttaacaaaa atattaaaac agctaaatgg
    16381 attaacctaa atgaaaaaga attagaatct atatcaatag ataataactt tgtaaatgta
    16441 gagtgcttaa tgaaccaagt taaaactata ttggttaaat agtgctaaaa aggaattgtc
    16501 ttaaaataga gataatcctc cttatcattg ttgaaataat aaacatatat ttgattttat
    16561 acaaaaagag tgtctcatga actaagaaat ttattttgag acactccctt tttataagat
    16621 aaaagaatat taatggtata agttgtatac aaagagagat gtagagtata aaataaaaga
    16681 taaattaagc ttataaaatt atatgtttaa aataaggagt aataaaaagg agtagataag
    16741 tatgaaaata ttaatttcta tagattcttt gaaaggaagc ttatcttcaa tagaggcagg
    16801 aaatgcaata aaaaagggga tattgaaggt taaagaagat gcgcaagtaa agatattgcc
    16861 acttgctgat ggtggtgaag ggacagtaga tgctttagtt caagggatga atggtaaaaa
    16921 agagactata gaagttactg gaccaatagc taaaaaagtg gatgcaacat atggattatt
    16981 aaaaaataca agtacagcaa taatagaaat agctcaagca tcaggactaa cattggttcc
    17041 gactgaactt agaaatcctt tatacactac aacttatggt gttggggaaa taataaaaga
    17101 agcaataaat aaaggctata gaaattttat agttgggata ggtggaagtg ctactaatga
    17161 tgctgggata ggtatgcttc aagccttagg gtttgagttt tatgatgaaa ataacaagtt
    17221 agtaggatta ggtggaaaag ttttaaatga aataagacat ataaaaatag aaaatagatt
    17281 aaaggaatta gatgaatgta agtttaaaat agcctgtgat gtaaataatc cgctgtttgg
    17341 gaaaaatgga gctgcataca tatacgggtc tcaaaaaggt gcaacatcag aaataattga
    17401 ggagttagat aatgggctta gaaatttttc caaagtagtt aaaagttact taagtaaaga
    17461 tgtagctaat gtagaaggag caggagcagc aggaggatta ggttttgctt ttttagcatt
    17521 tttaaattca aaattagaat ctggaataaa aataatatta gaagaaatta aattagagga
    17581 agagttaaaa gatgcagatt ttgtcataac tggtgaaggt agattggaca atcaaactgc
    17641 tatgggcaag gctccaatag gagttgcaaa actggcaaaa aaatatgggg taaaagtaat
    17701 aggtttggct ggagccacaa cagaagatgc agttaaatgt aatgaagagg gtatagatgc
    17761 ttatttttct atagtaaata gagctatgac aatagaagaa gcaatggata aagcaactgc
    17821 tagtgagaat atgacatcta caacaacaca aatattcaat cttataacta gtatacaaca
    17881 gtcaaaaaat atgtagtatt aaaacaaggt atattaggta aaaagctgtc acatattaat
    17941 ttagactttt tagtgtgaca gcttatctat tttatgttaa taacttaaga aacatatatt
    18001 ggaaataaat taacggattt agatattttg aataagataa gctattctat tcataaaact
    18061 actatagtta tctgccttag taagttcttt aacattattc cactcagata atatttcaat
    18121 aaagctttca aatatgtaat tgaatttttc tttttctttt tcatttatag gtatcatagc
    18181 tataatctga actttttcct caccccattt aactggttta tcgttaacaa ttaaacatac
    18241 tccagttttt aaagcatcca ttttcatgct atgaggaatt gctacattgt tattaaatgc
    18301 agttgaagac attttttctc ttataagaac atcatctata taattgggtt tgacatattt
    18361 attttcgtac agaatatttc ccataaattt tatataatct ttagcactat ctaaatatat
    18421 atttttcata aacaaagatt cactaaagta catttctaaa tgattttgta cagtaagtat
    18481 atttttttta tctttaatct gaataaattt actttggata ttatcataat cctttctatt
    18541 taggtaagga tttacataaa caaaaggtat agggcatcta tcgttaattg gtaaagtagt
    18601 aataaccatg tctaccttat tgtcaaaatc aagattatga gtatctgaaa aaatctgaat
    18661 aatttctatg gattcattaa atctcttctc gaggtctctt actattttga attgtaaatc
    18721 atagtaattt ggagtaatta atgcacatag aactttatct tctaataatt tttgtctatc
    18781 aaagaatgaa cctacatgaa gagatatata agatatttca tcttcgtcta tatctacatt
    18841 ttctaaagtt tgaatctgat tgcaaatata aacagatata tcatatatca aagggtagga
    18901 atcttttaac ttttgaggta tttgatttct taaaacttga ttatttttgg ctctactgat
    18961 taaatttttt acatgaagag taaattttac aacaaattcc tcatcagata aatctataag
    19021 atataagtca tatacatttt taattatttt tttagttaat ttaacaaagt gatcatctat
    19081 ataatttggc aatgacttag tatccatttc atgataattt aagactgtgg ttttgtttgt
    19141 taactgaaat actaagtagt ataattctgc actagttaaa gttatattgt attcagactc
    19201 taaaaaattt gatatatctc ttgaaatgct tatatcatta ttattatcta tgtagtttac
    19261 tacttcgaca gattctatgt agttattctt ttttattctg tctatagtta tcattaaatg
    19321 aagaagtatg ttatttatag catactcatt tataaacaaa ttgtattttt ttaatatata
    19381 tattatattt tctttcagtt tggtcaaatt atactcttga tatatttttt gtacatcaaa
    19441 taagcttaaa aaatcacttc ccgtttcttt aaatattata gagctcatta atttgcgctt
    19501 tgcagactca tttccaatta gtttcaataa aaatttcgat tgctttatct ttaaattata
    19561 acttcctata aatttattag ctttgactat atccccttca atagtagctg ggctaacaaa
    19621 caattcttca cttaaatcaa atatattaat tccattacta ttaactataa gttcttttaa
    19681 aattaaattt aacctgttat caggtgatat attttctgaa ctatcaacct tggtttgaca
    19741 attattattg agatttactt tatatccttt tttagaggat aatataaatt caccattgga
    19801 attaatttcg tttacatatt ttctaattga acgcgttgag acattaagat aattagccaa
    19861 tgtagatgaa tctatccaat catgttgtgt ttttatgaaa tttaaaaata gttctttttt
    19921 agatgttttc attagattcc ctcgcatagt tttaaaataa aatctggatg atatgataat
    19981 tatataattg aatgtacgta ttataagata cattatacta tattaatatg tttaattaag
    20041 agtaactgat ttcctattat taggaaatat atttatgtga aatgaactt
//
LOCUS       DAEOTL010000075        20030 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEOTL010000075 DAEOTL010000000
VERSION     DAEOTL010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20030
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.075"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(147..1178)
                     /locus_tag="KRH82_002983"
     CDS             complement(147..1178)
                     /locus_tag="KRH82_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBG8656250.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPKEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            1366..2256
                     /locus_tag="KRH82_002984"
     CDS             1366..2256
                     /locus_tag="KRH82_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBG8656251.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            complement(2308..3234)
                     /locus_tag="KRH82_002985"
     CDS             complement(2308..3234)
                     /locus_tag="KRH82_002985"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBG8656252.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(3449..4033)
                     /locus_tag="KRH82_002986"
     CDS             complement(3449..4033)
                     /locus_tag="KRH82_002986"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBG8656253.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            complement(4118..5020)
                     /locus_tag="KRH82_002987"
     CDS             complement(4118..5020)
                     /locus_tag="KRH82_002987"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBG8656254.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            complement(5013..5705)
                     /locus_tag="KRH82_002988"
     CDS             complement(5013..5705)
                     /locus_tag="KRH82_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBG8656255.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            complement(5744..6664)
                     /gene="pyrB"
                     /locus_tag="KRH82_002989"
     CDS             complement(5744..6664)
                     /gene="pyrB"
                     /locus_tag="KRH82_002989"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBG8656256.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            complement(6960..7982)
                     /locus_tag="KRH82_002990"
     CDS             complement(6960..7982)
                     /locus_tag="KRH82_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8656257.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            complement(8453..9592)
                     /locus_tag="KRH82_002991"
     CDS             complement(8453..9592)
                     /locus_tag="KRH82_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBG8656258.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDGEIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSDEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKYDMEKLHVFRGSVTLLEF
                     TYADAPENVKKEHKRMYEAMGLIPKDSDKISFGVKYYDKLNNLLR"
     gene            complement(9922..10413)
                     /locus_tag="KRH82_002992"
     CDS             complement(9922..10413)
                     /locus_tag="KRH82_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBG8656259.1"
                     /translation="MDLDCEFYCDERVLKNCTVQQKQEYALTIVNSMKRGTNFSNKFV
                     AGLNKQSDIRKRVINMFSEKYKNGILMALIISLFSSITFFKFDSTSIIEENDFLERSR
                     YTFEGRQEDVFVTIDFIYADAPIKLRKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMD
                     LKK"
     gene            complement(10397..10510)
                     /locus_tag="KRH82_002993"
     CDS             complement(10397..10510)
                     /locus_tag="KRH82_002993"
                     /inference="COORDINATES: protein motif:HMM:NF017390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656260.1"
                     /translation="MHFKSKDFHLKYLVLFLKIVYWFNPFIYNGKIYGFGL"
     gene            complement(10723..11988)
                     /gene="gluD"
                     /locus_tag="KRH82_002994"
     CDS             complement(10723..11988)
                     /gene="gluD"
                     /locus_tag="KRH82_002994"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBG8656261.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            complement(12117..12941)
                     /locus_tag="KRH82_002995"
     CDS             complement(12117..12941)
                     /locus_tag="KRH82_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8656262.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHREEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13216..14403
                     /locus_tag="KRH82_002996"
     CDS             13216..14403
                     /locus_tag="KRH82_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8656263.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNTRIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            complement(14542..15768)
                     /locus_tag="KRH82_002997"
     CDS             complement(14542..15768)
                     /locus_tag="KRH82_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBG8656264.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDICY
                     ADFFNIKENGEFCYSV"
     gene            complement(15743..16216)
                     /locus_tag="KRH82_002998"
     CDS             complement(15743..16216)
                     /locus_tag="KRH82_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBG8656265.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSKHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRS"
     gene            complement(16209..18110)
                     /gene="cooS"
                     /locus_tag="KRH82_002999"
     CDS             complement(16209..18110)
                     /gene="cooS"
                     /locus_tag="KRH82_002999"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBG8656266.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            complement(18495..19835)
                     /locus_tag="KRH82_003000"
     CDS             complement(18495..19835)
                     /locus_tag="KRH82_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBG8656267.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVRFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT         6580 a         3547 c         2073 g         7830 t
ORIGIN      
        1 taaattttta ccttaaataa aaaatgaatt tctataagtt tatacccact taaacttatc
       61 gaaattcatt ttttatttat attataaatt attagtatca tattatttta attaatcaaa
      121 ttagtattac aaatactatt tttatactat ataaatattt ttattaaaac tacagctgat
      181 acaacttgta ctgtacctac aaataaacca tataaagaaa cttctttccc ttgtttcact
      241 aaatctttta cattaacctt taatccaatt gctgctaaag ctattatttc tagtttgtta
      301 cttatttctt tgcacaacac agatacttct tttggtataa tgttcattga aaaaagtgca
      361 caagttataa agaatccaat tacataccat ggtatagtca cttttttctt ttttatctca
      421 tccttttctt cttcaagaat ttccctatta gattgatttt tcatatgtcc aaatactaat
      481 acaacaacaa ctagaaatat tactcttact atcttaaaaa tagtagctaa atcttttaca
      541 ttttctccaa caattgctcc acttgctaca acctgaccaa ttgattgcaa agttccacct
      601 atcattgctg aagtttttac aagttcatgg ctatataaaa attgagatat tattggaagt
      661 aaaaacataa gaaatatacc agtaacattt acaatagtta ctgcaattcc cttttcttta
      721 tctgtcgcat taaccactgg aactgttgct cctattgcag aagaaccaca tactgcattt
      781 ccacttgcca ttagaaatct aaagttttct tcaaatccta gttttttacc tatataaagt
      841 gcagctatta ttgttattgt catttgcaat attataaata aaattcctga aacttttaag
      901 tctattaaag tagatacact gagtgttgct cctaatagta ctattgaata tgataacaaa
      961 tctgtctctg aaaatttata acctttttga aatacctttt gatttaaaaa taggtttcct
     1021 acaaacatac ctaaaaatat agaaattgat gctgccccta ccttaggaat taaaatagaa
     1081 ataaatatac taatataacc tactaatact gatacaaaca gtcctggtaa tatttccctt
     1141 atagttttta atgtcaaact gctttttttc tttaacataa tatacctacc ttataattaa
     1201 tatagttttc ttcatagcaa tagtatataa ttgtaataac cataagtaaa ataaatatat
     1261 aatatcgtaa tgattaatgt ttttaatggt tattatatat agtataatta tctgtagaaa
     1321 gtatataaaa aatgtaaaat ttcattaggt aaaggagaca aaaaattgtt tgaagaatta
     1381 aaaacatttg tagctgttgt tgaatacaaa aactttacta aagctgggga atatttaaat
     1441 ctatcacaac caagtgtaag taaacacata aaaaatctag aaaattattt taaagttgtg
     1501 cttataaaca ggtctattaa acaaaaaacc atttttataa cagaaagtgg acaaatcttg
     1561 tacaaaagag ctaaagaaat attaaatctt ttaaatatta cttatcatga tgtaagccaa
     1621 gtttcagatg ctataactgg tcacttaaag attggtgcaa gtttaactat tggagagtat
     1681 attttaccaa attttctagc attattttct aaaaagtatc ctgacataga tgtagaagtt
     1741 tttataaaaa atacatcaat cgtatcttct catgttaagg attatatttt agacattggt
     1801 cttattgaag gcacttgctc ttccccttca tttattcaag aatatttttt tgaagataag
     1861 atggttttag cacttccata caagagtcat ttattaaaag attttagttt tgataaactt
     1921 caaaaccaaa aatggatagt cagggaggat ggttctggaa ccagagatta tttagatatg
     1981 tttttaagtg ttaaagaaat tattccaaaa agtatgatgg tttttggaag taattatgct
     2041 gtcaaagaat ctgttagaaa taatttagga attacaatag tctctaatct agtgacaagc
     2101 ttacctgttc taaacaatga gctgtctgtc atagagcttg gaagcagcta caacagacat
     2161 ttctcatata tatttccaaa agatataact ttatcaaaag cagcaactat tttcattgaa
     2221 gagttaaaaa tatttagtaa cttaaatagt atataacatt aataaaattt aaaatcaata
     2281 attatcaata tttcttacaa agacccttta aaatctactt tcaattactt ttatcatata
     2341 aaagaaagtc tgatttatag gagtaggtat gttatatttt tttccaagtt tgcagatatt
     2401 cttagaaaac atatctactt ctgtaagtct atgagcttcc acatcttgaa gcattgatgt
     2461 tcttccttct tttgaatgtt ctagtattct atgtaatgaa tgttccacat catcttctgt
     2521 aagagatatg tcttttgctt gtgctatagc aacaacttcc ctcattgcag attttgctaa
     2581 ttctcttaaa tgctcagaac tctgaaaaac tccataaggt gcaccaagta tagctgaagt
     2641 ttgatttaca ccaatattaa ccatgtactt ccaccacata tctcgttgaa tatcttttga
     2701 taaagtatat tctatattta catcatcaaa gacttcggtt attatattag tttttctatc
     2761 ttcactatta tctttgttac caaatacaat tatcccatta gtagtgtgta taatattatt
     2821 attgattttc tttgcatcta tattggtaac atatgaatat accatttttt caattccaaa
     2881 tctttctcct attatctctt cgctatcaac tccatttagc agagacatta taactgtatt
     2941 ttttccaact aatccatcta attcttttat attttctttt aaattattat attttagacc
     3001 tataattata aaatcagcct cttgtttata ctcatcttta gttacataat caaaatcata
     3061 cctttttcca tttattataa atccttcttc taaatatctt ttctttcttt cattatcaca
     3121 aagaatttta aaatcatatt tagagttaaa aaattgttct gcaaaagtag ctcctacagc
     3181 acctactcca aaaaatacaa cctttttatg attttcattt aattgatttt tcatacttac
     3241 ccctccctaa tatataatac ttttacctta tacttatatt gtactgctac tatctcttat
     3301 tttgtaaata tatttttaac aaaaaaaaca gctaaccttc atttataagg ctaactgctt
     3361 tttattttta agttatatgt tatattacaa atttttactc taaaaaattt acatttttta
     3421 agtaacacta taaataatta agtttttatt acatccctaa ttccttgaac tccctacttc
     3481 caggcttaac aactggtaat tttccttcct tacataaagg acactcatca gattcataaa
     3541 cttgaatatc aagttttata gcactatata taggcatacc tatatcatga ttagttctat
     3601 ctgctataca tgcaacacct acaacttctc cacctaaggc ttctaatact ctttttgtct
     3661 ccatagttga tttaccagta gttacaacgt cttcagcaat tattatcttt gctccttttt
     3721 taacttcaaa tcctcttctt aactccattg tattgtcttt tctctcagta aatacagctt
     3781 cttttcctaa ttgtcttcct aactcataag aaactattac tccacccata gctggtccta
     3841 ctactaagtc tatatctaag tcttttattt gttcaacaac tgtacttaat acctcagcag
     3901 catattctgg aaatcttaat acttttgcac attgtacgta tctattactg tgttttcctg
     3961 aagataataa aaaatgtccc tccaacaatg catcactttt ctttaatata tccactacat
     4021 ctactttact catattattt ttcctccatg ttaatgttat aaaattattg tttatttaat
     4081 ctatattttt tatctttaaa atactattta ttctacctta tataattcct cttatttcgt
     4141 ctaaactttt tattccttct ctatccataa attcattaat tccatctatt atttcaatac
     4201 ctattctagg attcataaaa tttgcagttc caacttggat acaagtagct cctgccatta
     4261 taaactctat agcatctgtg gctttagtta ttccgcccat tcccattaca ggtatattta
     4321 catttttaca cacttcatgt accattctca aagctatagg ttttatagct ggtccagata
     4381 acccagcata tacattttca aatactggtc ttctattttt tatatcaatt gccattgctt
     4441 taaaagtatt aactaatgaa actccatcag caccttcttc ttcacaaact tttgccattc
     4501 ctacaatatc ttctgcattg ggtgataatt ttattactaa aggcagtttc gttatgtttc
     4561 ttacctcacg aacaacttct cttgccactt cattttttat accaaaagcc attccaccag
     4621 ctttgacatt tgggcaagat atatttaatt caataatgtc tataggcttg tcatttaaca
     4681 tttgaacccc taataagtag tcttctaatg tcccacctcc aacattagct attctgacta
     4741 agtctagttt actaaaaaaa ggtaattcat agtctataaa tccttgaact ccagggtttt
     4801 caagcccaac actattcatc ataccggatg gtgtctcatg aactctcata ccattgttac
     4861 caggtttttt atttaaagta agacccttgc tacttatacc accaagtttt tgtatatcat
     4921 aaatctcatt atattctttt ccaaatccaa aagttccaga cgccattatt actggatttt
     4981 taaattctac acttccaaat ttcacactta aattacccat taaaaatcac gtcctctccc
     5041 cagaacactg gaccatcttt acaagtcttt ttatttcctc cattagtttt acacgtacat
     5101 actaaacagg cacctactcc acaagccata tggttttcaa gagataccat aattctcgtt
     5161 ttagtacctt ctaccatctt aactaatttt tccatcattg gagttggacc acatgttaat
     5221 atataatcat atttctcaac atcaattata tctgttacaa aagtatttcc tactgttgta
     5281 tagactttat tacatacttg tttatattca tcttctaata taacatcttc tctaaaccca
     5341 agatatgcat cacaattttt tatattttta gcaaccaaat atagtggagc tacaccgatt
     5401 cctcctccta ctagagctac ctttccatca accttagcat atccattacc ataagggcct
     5461 tctaatttta tattatcatt tacctttagg ttactcaaaa tttgagttcc ttctcctact
     5521 actttataaa gaaaagttat cccttcttca tctatatcat gtatacttat aggtcttgaa
     5581 agtactggat aagtatccca tgctcttaac atatagaatt gtcccatttt accttcaaaa
     5641 ttacctttta ctttcattct atacatatct tcgcctatat atatattttc cagaatttta
     5701 tacatcccaa aatctccttt gttttactat tatatgataa ctattagtct tcatttatac
     5761 ctaaaagttt tattattaaa gccattctaa catacattcc atatttagct tgtttaaaat
     5821 atacagctct atcatcacta tctacatcta tgtctatttc atttactctt ggtaatggat
     5881 gcattactaa catatcttta gatgcctttt ctaatttagc tttatttaaa atataatagt
     5941 ttttaagtct ttcatactct gatttatctt caaatctttc ttgttgaact ctagtcatat
     6001 ataaaacatc caagcttcct ataacatcat ccaaattatt agtttcataa tatgcatgtc
     6061 cctttatagc ttcttttata taatctggca tttttaactc ttcaggcgct ataaatacaa
     6121 actttgtatt tttatatctt gccatagcct taaccaaaga atgcacagtt cttccatatt
     6181 ttaaatcacc acataatcct attgtatggc tttctaaagt tccttttaat gattttatag
     6241 taagtaagtc tgtaagtgtt tgagttggat gctggttctt gccgtctcct gcatttataa
     6301 atggcacttc cgtatatcta gctgcttctg aagctgcacc tgattgagga tgtctcatag
     6361 ctattatatc aacataacca gatactatcc tcattgtatc tcctagagtt tcaccttttg
     6421 atgcagagga tgaatttggc tctgaaaagc ctactacacg tcctcctaat ctgttcatag
     6481 cagattcaaa gcttaatctt gttcttgttg atggttcata aaataatgta gctaatagtt
     6541 ttccttcaca tatacgagaa tattttgacg gattgtcaat tattttttga gctaattcta
     6601 atatttcatc tatttcttct attgaaaagt cttctggttg gattaaattt cttgatttta
     6661 acatctttcg tcctcctttt ttagcctctc tgaactaaaa ttaaaagtat ttttgtactg
     6721 ttagtagctt accacctttg ccctatcctg tcaagggatt gcgcaaataa tcatcatatg
     6781 aaaaggctcc tatttaacag tcatattaac ttgaatcttg attagattta aagtgataca
     6841 aaaacgctct atagtacatt taaaatataa tcattttttg tttccatgat taaattaaat
     6901 ataatataga gcgtttatat atatttatgt atttatcaat ttgtcatatt acaaaccgat
     6961 tataatattc tttttgctgt aacaaatctt gctgtatagt atgatgaatt tatactagtt
     7021 acactaactg tttttcctgt tgatggtgaa tgtatcatat tacccccacc tacatatatt
     7081 ccaacatgac taacagaacc agaaccatta gttgtgaaga atactaagtc tcctggttgt
     7141 aaatttgctt tacttacagt ttgtccatat ttagattgtg ctttagatgt tcttggtata
     7201 ttctttccta ctgcatttct atacacatat tgtgtaaatc cagaacagtc aaaagtgttt
     7261 ggtccttctg ctccccaaac atatggacaa ccttgcttag aatatgccaa gttaagtaca
     7321 gcttgaactg cattagagtt agctgttggc acatttgaat tattattttg ttgattagta
     7381 tttgcattgt tttgttgatt attatttgta gaatctacat tttggtcaat acttgggttt
     7441 acttgtggct cttctattac aggagcttta tcagatatat aagatgattt tacatatcct
     7501 tctgtttccc catctttaac ttttaaccaa tctccattat cttccaaaac caataaagaa
     7561 cttccttttt ccagctcttc aattacttct gaactttcac tcttatcttt tcttaagttt
     7621 actttatcag cgttagtata tcctacacct tcagatatat ctacatatct agtagctaac
     7681 caaccttcgc catcttcaac tttaacctta acccattctc cttgagttcc taaaaccgta
     7741 aattcatctc cagaataagc tatgttttga acttgacctt cttctcttat ctttatagct
     7801 actccatctt ttatttttgc aactttatat tttacttctt tatattcacc taaatttaat
     7861 tcagtatttg ttttatcatc cttattttga gatgaatcat ttacttcatc tgcatttaca
     7921 attgaactta ctgataatgc cataactgat gcaaatactg gtattaatat ctttttcttc
     7981 acgataaacc tcctaaaatt ttcccataat tatcttatga ttctattttg taggtgaagt
     8041 gtacctaagg ataaaatact aatacacaat acattaataa aagctctatc tgtaactttt
     8101 ttgtaaacca ctttatataa cttttatagt attattatat taataaaata aataaattag
     8161 cttatccaat atgtcaccta aatatacatt atttacttaa ttatataata tgggtctgta
     8221 aaagtaaaga attttgtacc attcgaggtt aaagtgcgca taaatattgt tttatgtgtt
     8281 tttttatgcg cttttatatg gcgtatattt tttgatgaaa taactataaa agttggttgt
     8341 tttgtgaaat tttttacaat tgaatataat tattaatact ttctttagga cttttgtgaa
     8401 tacttacttt taaattcttt taagtttcag ctatttgcta ttatataaat atctatctta
     8461 ataaattgtt caacttgtca tagtatttta caccaaagct tattttatca gagtctttag
     8521 gaatcaatcc cattgcttca tacattcttt tatgttcttt tttaacattt tcaggagcat
     8581 ctgcatatgt aaattctaaa agtgtaacac ttcctctaaa aacatgtagc ttctccatat
     8641 catatttagg caatatatta agattaacaa tactcgttga attaaccttc aaaaaagtaa
     8701 tagaagataa taaacataaa gttaatgcca ttaatatacc attcttgtac ttttcattaa
     8761 acatattcat aactctcttt ttaatatcag attgcttatg gagtccagct ataaatttat
     8821 ttgaagtatt tgaacctttt ctcattgcat ttagaattgt taaagcataa tccttttttt
     8881 catctgaatt tcgatttttt aaaactcttt catcacaata aagttcacaa tctaaatcta
     8941 tatgtttatc cattatatat ataaatggat taaaccaata tactgttttt aaaaacagga
     9001 ttacatattt taaataaagg tccctactct taaaatgcat aagctcatgt ctaaaaatcc
     9061 agtctaactc tttcaattta tactcatgtg gtggcaaaag cacacatgaa ttaaaaaatg
     9121 ctggtgtttc aacttcataa gagtatttga gttttatatc ttttgttata ttaaattctt
     9181 ctaatatatt tttataaaga tttacaatct ctccatcatc aacatcataa gataagtcat
     9241 ttattaaatt tttaagtttt atatatttaa atatagtgta aattaaataa actactacag
     9301 ttataatcca agtgtacaat ataatattat tacttatagt tgaaacatta ttaaatccct
     9361 ctaaatttat gttattaata ttaatgtgtt ttttacttct caagatattt attgtaaaag
     9421 tataatatgt aaatggtaaa aataatttaa taacaactat catccatata taataattaa
     9481 attttttgct aaatctttta aatacatttt tcttgaaaat caatatcata agaatgctta
     9541 gactacttac tataactgtt ctaaaaatcc catttagaat aaagttagac atacattttt
     9601 ctcctatctt atttaagagt attttatgtt taagtttatt tgccttttaa gttttcatat
     9661 tatctttatt aattaaaaag atacattttt tgtaacagat aactattttt atcattttat
     9721 aattgtgtaa ctcataattt atttaaactc ccctataatt aattatagct tagtaatgat
     9781 tcctatgcat caatcatatt taattatttc aactatctat aaatttcata cttaaacacg
     9841 tataaaattg aatctataat aaaattttca attgcttaaa tataaaaaat tcataatatc
     9901 aacatcaata ttaagtctaa cttatttttt taaatccata caatctttat aaaatctagg
     9961 aataatttct attgaatctg aatcttttgg tactattcca ttgactctac agttttcttc
    10021 atgctctttt ctaagtttta taggtgcatc tgcatatata aaatctattg ttacaaacac
    10081 gtcttcttgc cttccttcaa acgtatatct tgacctctct aagaaatcat tctcttcaat
    10141 aatactagtt gaatcgaatt taaaaaatgt aatagaagaa aacaagctta taatcaaagc
    10201 cattaagata ccatttttat atttttcact gaacatgttt attactcttt ttctaatatc
    10261 agattgttta tttaatccag ctacaaattt atttgaaaaa tttgtacctc ttttcattga
    10321 atttacaata gttagagcat attcttgctt ttgttgtaca gtacaatttt ttaaaactct
    10381 ctcatcacaa taaaattcac aatccaaatc catatatttt tccattatat ataaatggat
    10441 taaaccaata tactattttt aaaaataata ctagatactt taaatgaaag tctttgcttt
    10501 taaaatgcat aagttcatgt ctaaaaattc aatctaactc ctctaatttg taatcatgtg
    10561 gtggtaaaaa atacattcta aattacataa tttatcaagt tctttataag ttaaaacaaa
    10621 aatagcttac ttcattgtaa gccacataat ttaagggctg tactatgtac agccccttta
    10681 tatcttaaat aattatatcc tattatttat taagagtaaa tcttagtacc atcctcttaa
    10741 tttcatagct tcagcaactt tcttaattga atgcatgtaa gcagcttctc tcattgtaac
    10801 attgtactct tctttgattt tccaaataga ttcaaatgct ttaaccatag ctatttcttc
    10861 tttttgctct acttcttctt ctgaccagta gtatccatat aagttttgta cccactcaaa
    10921 gtaagaaact gtaactccac cagcattagt taatatatct ggagtaagaa ctattcctct
    10981 ttcagcaaat acttcatcag cctctggagt agttggtcca ttagcagcct cacaaactaa
    11041 tttagctttt atagattcag caacttcttt agttatagag ttttctaatg cagctggtat
    11101 tactatatca acatctgaag cccagaactc ttctaaagat attctcttag ctcctgggaa
    11161 gtttaataag ttaccatgtt ctttcatata atctaacata gcttgaccat ctaaaccatt
    11221 ttcattgtat atagcataag aaccttctga tttacaccat tcagccatag ctacaacagt
    11281 accaccaagt ttttcacagt taagaactgt ataagaacca acgtttccta taccttgaac
    11341 agctatttta gcttttttca tatctattcc taatttagca gcagcttctc ttgctgtaac
    11401 agcaacacca aatccagtag cagctgttct tcctaaagaa ccaccaaatt caactggctt
    11461 accagttata acacctatag aactttgtcc agttaattta ttgtactcat caaccatcca
    11521 agacattatt tgaccattag tatttacgtc tggtgcagga acgtcaactt tctcacctat
    11581 taatttatat attccatcta tgtatcctct acttaatctt tctaattcac cttgagataa
    11641 agttgatgga tctactatta ttccaccttt acctccacca tatggtatac ctgttacaga
    11701 acacttgaaa gtcatccata tagataaagc ttttacttcg tctcttgaaa cattttgatg
    11761 gaatcttatt ccaccttttg ttggccctac tgcatcatta tgttgtgatc taaatccttt
    11821 aaaagttttt atagaaccat catccatttt tactggaatt gaaacctcta taactctcat
    11881 aggttctttt aataattcat aaactgctgg ttccatacct aatttatcac atgcattttt
    11941 tacttgagat tgcgccatct cgaagacatt tacatctttt cctgacattt gaaagccccc
    12001 ttataaatac gttataatta tgtatactcc atttagaaaa aaccatttcc taaatttaca
    12061 gtttaattat agcacacttt attgcaaatt agtatatcat tttctcagtt tattttttaa
    12121 cattggagga agtttatttt tttaatttta tgaatgttaa tatctatttt ttgtacatta
    12181 actaaagtca ttttctcaat agactttttt attgtctgtt gtatgtcttc aatttttttt
    12241 atagtttcta aatcattgat atttatactt acaaaaatat tcataaaatt attgcaattc
    12301 tctatattga ttttatttat tctatcaatg cttccaaagt tgtatacttc atattcaata
    12361 atctgtttaa ttacatcagc actaatataa aactttccta tataactaaa agttggtctt
    12421 ataattgttt tttctaaaac taccatattc ctattatttc cttttctaaa aagtctcttc
    12481 aaagaattta tactaagacc acttgccata ctttttatct caactgctgg aacaggaatt
    12541 acatgatttc cttcttttct agcttgtttt gctatttcta tctcatattt agtacttata
    12601 tcttgtatat ttataaactt acagaccctt ccaattgaca atctctctac aatttgatta
    12661 accatttttt ttgatgtccc aataataaga atttttctta tattttcttt tttaattgct
    12721 tctctaactt cttctctatg ctccaaatta taaaaaatag cccttttaac tgcttctata
    12781 gtagtatttg cttgttttgc cgatatccca gctaaaacct tgtttttgta tattaaaatc
    12841 ccatcatcga ttatatattc tatatcattt tcatatgcga actctaaagc cttaaagctc
    12901 ttccctgtgc cacttgaccc aaccaaagca tatacttcca tcctacatat ctccttataa
    12961 aatagcttta actatttatt acaaaatttt atttacttta tagattaaat ttattatatc
    13021 attaacagtt taatattata tccagtacca aaatttataa gcaaaaaata tactacaaca
    13081 tgaaatttct ttataaaaaa taaatttcct ttaaataaaa aatttattga aaaaatttta
    13141 cttttttaaa aaaaggacta taatatattt taagcaggga aacttactgg atttacatta
    13201 gaaggagctg gtaatatgaa tattacaaaa aattttttaa aagactattt agagagattt
    13261 ggtgaaacac catttctagt taggcttaaa gatgaggaag aatttctaat tggagagggc
    13321 tcccctcagt tcaaagttat agtaaataat gatattagca agtctgaact attaaaaagt
    13381 acatctttag cacttggaga agcctacata aatagagaca ttgaagttga gggagattta
    13441 ttcttaactt taaatctact tttaaaacaa atagacaaat tcaatattga taattcagct
    13501 gtaaaacatc tattgcactc atcaaattca atgagacatc aaaagaaaga aatacatgcc
    13561 cactatgaca ttggcaacga tttttatagc ttatggttag ataagacact tagttattct
    13621 tgtgcatact ttagaaatga taatgatact ctttatgatg ctcaagtcaa taaagttcac
    13681 cacatattaa ctaaactaaa tttagaggaa ggtatgagcc ttctcgatat tggttgtggt
    13741 tggggatttt tactaataga agctgcaaaa aaatataaaa ttcacggcgt tggaattaca
    13801 cttagcgaag agcaatttaa ggaatttaac acaagaatta aagaagagaa ccttcaagac
    13861 tatcttgagg taagacttat ggactataga gaattaaaaa aatcagacct tatgtttgat
    13921 agagttgtaa gcgttgggat gcttgaacat gttggtagag aaaactatga acttttcatt
    13981 aaaaacgtaa atgctgtttt aaaagatggt ggattgtttt tacttcacta tataagtgga
    14041 ttgcaggaat cttatggaga cccttggata aaaaaatata ttttcccagg aggagttatt
    14101 cctagcctaa gagaaatgat acatatttgt agtgattaca aatatcatac tatagacgta
    14161 gaaagtctaa gattacatta tgtaaaaacc ttactatact ggcaaaaaaa tttctctgag
    14221 aatcttccaa agattaaaga aatgtttgat gataagttta taagaatgtg ggatttatac
    14281 ctttgttctt gtgctgctgc tttcaacact ggtattatag atatacatca aatacttttc
    14341 actaaaggta taaaaaatga tttacctcta actagagagt atatgtataa ttgttcaaaa
    14401 taatatttta caaattgaat ataatttaaa tttaattaca aaaaatagag ctatttctaa
    14461 ataagatttg tcatttttct tattttagaa taactctatt tattgattta ctgtatttat
    14521 aaaccttact ccacgtatat actatacact ataacaaaat tctccatttt cttttatatt
    14581 aaaaaagtct gcataacata tatcaaatat cctattttct aaatcatata tttcaacttt
    14641 attttttatt aaataagtta atacacctac atatgaaata tctccttgta taactgctcc
    14701 atagattaca ttatctttaa aaacaaactt tttataatca ttaattccat gtctggttaa
    14761 tactttatag ctatcatcta caggtgtatt cattcctata gaaatagttg gtatatccat
    14821 gaaattcata ctatttttaa aagcaaattc atcttctatc ttcttatctt ttccaaccat
    14881 attataggca gctacaattc cttgctttac tgccagaggc caaatagcat ttttacctac
    14941 aacatctcct gctgcatata tgtctttttg tgttgtttgg cacatatcat ctattattat
    15001 acctctatca tattctattc ctgttccatc taaaaagtca gcatttggtt taacccctgt
    15061 agctacaatt accatgtctg catctaaaac ttcaccattt gaaaatgcaa cacctgtaac
    15121 attcttactg ttatccaata caatttcttg tattgatgca cttgggtaaa attttacacc
    15181 tttttctttg aacttatttt catacactga tgctgtatat tcatccaatt gtctatctaa
    15241 aatgtacttt tccataaaag ctacagaaat atttaactgc tcatatttaa ataatcccac
    15301 taatgcatct ataccaacta aaccagcacc tattataact acatttttag aattttgtgc
    15361 tttttctttt attttataaa tatcatctat gtttctcaca gaatatacaa aatttccatc
    15421 tcttaaattt tttataggag gaatagcaga agatgcacct gtagctatta aaagtttatc
    15481 ataatttaca gtaatgtctt ctgtctgaac taccttttta tttatgtcta tacctttaac
    15541 agtcttacct gcaatccatt ttacattatt ttgctccata aaatcttcat caacaaaatt
    15601 tatttgtttt aaagttctgt gttcagatat aacgtgatgc aacatacatc ttgagtatac
    15661 gttttcatct ttagaaatta ctactatatt tgaatcttta tctaattctc ttaatgtttt
    15721 tactgcattt ataccagctg cactagctcc taacactaca taattcatca ttttcctcct
    15781 tctgtaattc aattgctcca cttgggcaat tagctacaca tctaggatac tcctcatctt
    15841 tacataaatc acatttaagt atgttctgct tgcttctatc atctggcttt aataatccat
    15901 atggacaaga cattacacac atataacatg aaccacattt ctcttcatca tatgaaacga
    15961 ttccactttc actatcttta tgcattgcac cactcataca tgctaataca cattcaggtt
    16021 catcacagtg tctacaaaga attggaactg gattattatg tttactatct aattctatat
    16081 gccctctact atcattatct atattttcta aatcaagagt gtacatgtca taatctttat
    16141 tgtgttttag catacatgct agtacacagc tcttacatcc tgtacataaa tctttattta
    16201 taaaaattct atgcattgca ttccacatcc tttaacccta aattttttct tctatctatt
    16261 attatttctt ctaattgatt agctgaagat ttagggtctg gattcactat aacatgtcct
    16321 cctgttaagt cttttaattt ttctgttaat acttctgtca ccaattttcc tcctgttata
    16381 aatggaggta aagctaaatg aagaggtaag ccaagggcaa gaccaaacgc tccatcagct
    16441 aatgcttgtt cttccaacca ttgtggagct gaaagcacta atggtaattg tggtaggtca
    16501 attccaagtt cagctgctaa ttctgttgct actatttcta gtcttcctat agctagacat
    16561 ggtccaaagt ttaatactgg tggtattcct aaagtcttac atacttcttt taagttttct
    16621 cctgctaatt cttctgctcc aggtgacata agaccaacat tttctaatcc tccagtagaa
    16681 catcctgcag atagtactat tatatctttt ttaatcaatt ctttagtaag ttcaacagta
    16741 tttacatcat gtcctcctgc tgtcatattt gaacatccta caacagctgc aacaccttta
    16801 atttttcctt ctgcaattaa attaataaga ggtttccatg aatctcctaa aaacgctttc
    16861 aggttctttt cacttacacc agttaaagat tgttcaaatc catggtcttt tggtatatct
    16921 atttcaatac ttcctcttct ctccttataa gactccaatg ctttttctat taaagtgtta
    16981 ctaagttcat ctaatttact tctgtctaaa cctatgtatt ctgcattcgc ttttttagca
    17041 acatcatcta aacaaaccat ttttacttta tatttatctg ctattggttc aagccctggt
    17101 atagtacagt taaattctga aagaactata tctattgctc cagttgataa aacagcctca
    17161 cttgtaaaat tgttacctgc atgtccagca aatacttctt gataatgttc tcctcttaat
    17221 tgtaaatctt gaccaacaca tgtacatcct actagcttaa agccttttgc accaacagat
    17281 tgagctaatt ttataacatc ttcatctttt aatctatctt ggaaatttgc aaatgttgaa
    17341 tgttgatggc ctgttatcat tatatttatg tagtctgggt ctattacatt aaatcctaca
    17401 ggagccattc ttataactgg ttctcccaac ataacatcat ttaaaagatt agttagtgta
    17461 agaccatata atcctgttga tatacctaag ttcaaacaat taactagcat gtctactggg
    17521 tcactattta aatttgttga tgattttact attgcatcaa aaacttctga ctttgcacca
    17581 ccaggcatta tacctaactc tttccacttt ttcactctag gtgcataagc tattttttct
    17641 actaattcca ttttatcatc tcttgattta tacaaatcgt tgataacttt gtctgcaacc
    17701 tttatacatt tatcatactt ttcatcactt tctattccaa acatctctgc taattgattt
    17761 aatgtttttt ctcctttaac aacaccttta gttattccaa cattttttaa attcttagct
    17821 gtattttcta ccacatgtaa ataacaagct gctcctgatg ctactgctct taaaaagttt
    17881 cttgctacta tagtgtctgc atctgctcca catatacctc ttggtgattt aggagttact
    17941 ctacatggtc catttgaaca gagtctacaa caaaccccct gaagtccaaa accacactta
    18001 actttctgat cttctgttct atgaaatgct gtttcaacat cctttgaagc tacaaaactt
    18061 tctaatttct tgtctgcact ttcgcacatt ttacaagtgt tacaagccat tacaaattcc
    18121 cccttatatt tttatattaa aaaagtagat taaatagctt tattataatt gactataatt
    18181 taactattaa aatctactta tttaatacca cgatttacca taccctaaac aaaatataaa
    18241 ttattaaaat aaatatatat attaaattct tatacaccaa atttttacat taaacttcta
    18301 tgcaccacat ttatacatat taaattctta tatattaaat ttctatgcat cacttttata
    18361 cttattaaat tcctatatat taaacttcta tacatcactt ttatacatta attcttatat
    18421 attaaacttc tatgcatcac ttttatacat taattcttat atattaaatt tctacacatc
    18481 aaatttatat acatttaaat cacatgatta actgctttct tcacatttct aagtggaata
    18541 gcaattttaa ctacaaattt tttatcatca tattcaatta caacattacc accatactta
    18601 tttacagagt tttttacact ttttattcca agtccatgaa gagaaccttt tttgtctgtc
    18661 aaaatatctc catttttagt aataatctta ttcatcttag tattttcaac tcttattaaa
    18721 taaaaatttt gcataacatc acctttaaca caaataactc tatttccact atcaatttta
    18781 ttacatgcct caattgcatt gtctaaaata tttgaaaata tatgacatat atccactaat
    18841 tcaacagctt cacaacaact aaaatttatt cctattttta gttctatatc attcttatca
    18901 caaacctctt tcttttcact taatatagca tctaatataa aattaccagt attaaataac
    18961 aagtcattac tctgaatttc tacctgcaaa ttatttaaat aagaagtaac atcaatacct
    19021 tttttaatca tagcatttat acacaatatg tgatttttca tatcatgact tagtaatcta
    19081 gtttttaaat atttcttttc tatatcttca taatactcat tttcatactt caaagtattt
    19141 ttaatcatat tgttttctac aactaaagta ttatattgct gtaatttttt agcaattaaa
    19201 actaaagtga tacttgatat aagcaataca acagaaatca taacgaattg gaaattatgt
    19261 attaagctac cagaccctgg attaaatatg tattcaaaaa ttacaaaaaa agatgctata
    19321 ttagcgacta taggaataac tatataaaat aatgtccttt tatttatttc tatattaagt
    19381 tttatcttta aggctctata taaaagcaaa gacacaatca aaagtatctt tcccaatatt
    19441 atagactcaa ttctgtatat atctcccgtc cccatactac tcatgtcatt tatagaatta
    19501 agccaaactg ttaaagatat actcaaagca tctgtggcga ttagtaacat ccaataaatt
    19561 aaggatatta atacagactt tataaacctc acatcatatg agattttata aaatgcaata
    19621 gtaattatca tagatataat tactcttata tttggaggta catcaaaaaa atatattatg
    19681 tcagcaaaaa caataatacc taccatacaa aagtttattt ttttgttaga aatccttttc
    19741 tcacttgtat aatctagcat tttcttacaa agaaaccatt ctatcataaa ggatatcgca
    19801 atgaaaatat tccaaaataa gcttgacttt atcataatac tttctcctaa cgtattacta
    19861 aattattttt ttatatttta tgtataattt aattatatac gactctacac gtgtagtaaa
    19921 tagattgtca aaattattcc aaataagtcc atatttcttt tcttttttaa ttatatcact
    19981 aaatttgcta aattgaatta aactttttat tgcttttttt aataataact
//
LOCUS       DAEOTL010000076        19837 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEOTL010000076 DAEOTL010000000
VERSION     DAEOTL010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19837
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.076"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            583..1911
                     /locus_tag="KRH82_003001"
     CDS             583..1911
                     /locus_tag="KRH82_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8656268.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2664..3497
                     /locus_tag="KRH82_003002"
     CDS             2664..3497
                     /locus_tag="KRH82_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBG8656269.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3590..4522
                     /locus_tag="KRH82_003003"
     CDS             3590..4522
                     /locus_tag="KRH82_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBG8656270.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4574..5056
                     /locus_tag="KRH82_003004"
     CDS             4574..5056
                     /locus_tag="KRH82_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656271.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            5068..5937
                     /locus_tag="KRH82_003005"
     CDS             5068..5937
                     /locus_tag="KRH82_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBG8656272.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5980..6735
                     /locus_tag="KRH82_003006"
     CDS             5980..6735
                     /locus_tag="KRH82_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBG8656273.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            6777..7598
                     /locus_tag="KRH82_003007"
     CDS             6777..7598
                     /locus_tag="KRH82_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XdhC family protein"
                     /protein_id="HBG8656274.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSGT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7603..8364
                     /locus_tag="KRH82_003008"
     CDS             7603..8364
                     /locus_tag="KRH82_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBG8656275.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIVVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8525..8782
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8895..9134
                     /locus_tag="KRH82_003009"
     CDS             8895..9134
                     /locus_tag="KRH82_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBG8656276.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            complement(9357..10547)
                     /locus_tag="KRH82_003010"
     CDS             complement(9357..10547)
                     /locus_tag="KRH82_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8656277.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYDKKNSQRKNIKRA
                     TEKGRQYLMNALKNDPLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEERLLAFMEKDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRVLNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILKNRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(10626..10829)
                     /locus_tag="KRH82_003011"
     CDS             complement(10626..10829)
                     /locus_tag="KRH82_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBG8656278.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENLDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(11205..11444)
                     /locus_tag="KRH82_003012"
     CDS             complement(11205..11444)
                     /locus_tag="KRH82_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656279.1"
                     /translation="MNNTRPSFYLISSAVDGNVNSIEKILAFYDPYISKCCLRPFYDR
                     YGNVCIVVDMELKGRIREALIKMMLDFDIPLETEE"
     gene            complement(11437..11865)
                     /locus_tag="KRH82_003013"
     CDS             complement(11437..11865)
                     /locus_tag="KRH82_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656280.1"
                     /translation="MKPSNFQRTIQCQFDCKLKRVVKGIVRNYRKELKRRRNKEISYC
                     ELPEIVVEKLAVWDEYESDYTAFDVCGIEVRVLDDDLAEAIKYLSEKDREILLMYFFL
                     GMSDTEIGDRLKINRSTSFRSRKNSLEEIKKKLKENMNDE"
     gene            complement(12146..12370)
                     /locus_tag="KRH82_003014"
     CDS             complement(12146..12370)
                     /locus_tag="KRH82_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656281.1"
                     /translation="MIGLKKRDIKKALKAGAKAGGVSLSDVRADIEATIDEAMNSTDP
                     EVQANFKKYFGNKRPTSEEYIYKITQKTKV"
     gene            complement(12642..14195)
                     /locus_tag="KRH82_003015"
                     /pseudo
     CDS             complement(12642..14195)
                     /locus_tag="KRH82_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584336.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(14182..14619)
                     /locus_tag="KRH82_003016"
     CDS             complement(14182..14619)
                     /locus_tag="KRH82_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006355510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HBG8656282.1"
                     /translation="MRASKLTARGLAYALRAVGRKIAKEHRKAQTPHGRQSVKKLMAH
                     GTAANSIELSGDTKLFDRVARKWNVDYAFFKTGPDKYLLFFKSGQADAMSACLSEYSR
                     KVLNKTKSRRIPIRDQLKRASEQLSREQPRPKERVQEVSHADR"
     gene            complement(14713..15426)
                     /locus_tag="KRH82_003017"
     CDS             complement(14713..15426)
                     /locus_tag="KRH82_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002593553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8656283.1"
                     /translation="MTSTLEAYITNLGKYVEGQLVGETLKFPTTPEEVQALLKRIGVD
                     GIRYGEIFITSFDSDVLGLCDHLGEYENLDELNYLAALLSEMDSSDLEKFEAVVDSGE
                     YSGTVKDLINLTQNLDCFEFYSGVRDDEELGRMYIQDFEALQIPEHLIDYIDYSGYGR
                     DVRINEDGHYAPGGYVMNNRSRFIEHYSGREDIPDEHRIFSYPKLNIREQMAAYKEVI
                     DRSALDAGKHYIGPAHAER"
     gene            complement(15428..15769)
                     /locus_tag="KRH82_003018"
     CDS             complement(15428..15769)
                     /locus_tag="KRH82_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002584339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656284.1"
                     /translation="MKRPLAYITAAWCGSDCENAKQAAQYCRFVYDAGFSPICPPLYH
                     PLFLNDAIPEEHKSGIDMGRDLLRCSHVLVVCGSTVTEAMKNDIAVAQRLGITATTLE
                     GILTVKGQGRR"
     gene            complement(16054..17328)
                     /locus_tag="KRH82_003019"
     CDS             complement(16054..17328)
                     /locus_tag="KRH82_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007887916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBG8656285.1"
                     /translation="MGEAIPDAPEFPGVTIPEQPEPDKPEQQASTPGKVVDFAAAREE
                     TGKATPPAKEVDPPDKEHKKPEQPRRGRPSKADKAAPSKADPAKKDKATPTKAEKPKR
                     DKMSQSKAPTPKEEAAAPAEPEQPAQPRDATRAEKEEIVYLNLSELHPFQDHPFGVRD
                     DAEMQGLVESVKAAGVNQPALVRPREGGGYEIIAGHRRQRASELAGFSNMPCIVRKMT
                     DDEAILAMTDDNLRHREKILPTEKAKALKQQVEAIKHQGARPGEDDKDAGKRSTQVVG
                     DRNGMNYKQVQRYIRLTELVPDLKKMLDEKQLAFTPAVEISFIRPKHQRYIAVAIEGQ
                     QSSPSLSQAQKLRELDKQGALNGDVIDGILSEQKKEVDKVIINSVELEKYFGKDKSPR
                     EMKDKIISLLDDWKAKQPPELGKPDKKKDMEK"
     gene            complement(17761..18720)
                     /locus_tag="KRH82_003020"
     CDS             complement(17761..18720)
                     /locus_tag="KRH82_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656286.1"
                     /translation="MIGMDNRFNKSWYGDKAQLVDSDNDCVIIDYGCKGKGIITSYNL
                     YDGITLCFLDFYTDEIMPSQKFNPDIISIVHCQAGRYECEFSNHQMFYLSEGYFSIMG
                     TKHLPISFSFPLKKCYAFSLVIDKHALSADTQKILNDFCLDMDKISERLKLNKNGYLS
                     HADFELGHLFEEFYNAKDKESITYFRVKAIEFLYFINKLSGNEETEFRYFNKKYIQIT
                     KDVCKYMTEHLEEKVSLEQLAYEKGINLSLLYKVFAQVYGDTPYSYIKKYKMNIASNE
                     LRNSKRKINDIALSLGYSNASKFSIAFQSVYGILPKDYRKAEN"
     gene            complement(18833..19744)
                     /locus_tag="KRH82_003021"
     CDS             complement(18833..19744)
                     /locus_tag="KRH82_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8656287.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELCLQDTNGIENFVKNFAKSYYTWNNSKEAIEARTQA
                     ISGYLTKELQDLNVDTIRTDIPTSSTATNVIVWSIEQSGTNTFSATYEVDQQIKEGEK
                     TSNVKATYTVKVHIDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATA
                     FLETFFKLYPTATEKELAYYVSGNVLEPIGRDYLYSELINPIFTKDGENVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDSNWKIIG"
BASE COUNT         6350 a         3477 c         3876 g         6134 t
ORIGIN      
        1 tatattaaaa aatatgaatg aaagtagtgg gttttataaa aaaacatatt tagattttaa
       61 catctaaaag gagttttcaa agctaatatt tcatttttaa ataaaaaaat aaaatattag
      121 ttttgatttc tggtttaaat tgggttataa taaattgtca aattatttat taatataaaa
      181 tagactataa aacaagcaaa aatcatacta ttatataaaa gaccttaaag atagaaaact
      241 acagaaagaa gccaaaatgt ttttgaaaaa aatgaaattt tattgaaaaa aaatcaaaat
      301 gaatttaact taatagttat aatctatttt tagtgttaca aatatacaat gtatattata
      361 caatataaaa aatacattta cttagaagta ttattatatt tggatttttg gtttttataa
      421 tttttttata tttaaacata gctaaaaata aaagattacg aaagctaagt agagtttatt
      481 ttattttaat aaataataaa gctatttttc tatatattgg cataatatat gcttatttaa
      541 ctatgaaatt aaaattaaat aggattaatg aggaggaaaa aaatgggaag taatgaactg
      601 aaaaagactc ttggcgtatc agcagcatta tcaactgttg ttggttccgt tataggagcg
      661 ggcgtatttt ttaaaccaca agcagtctat acattaactg gaggagctcc aggtcttggt
      721 atattggcat ggttaatagc tggaatcata actataacag ctggtcttac agctgcagag
      781 gtatcagttg cgataccaaa aactggtgga atgatggtat atataaaaga aatttatgga
      841 gaaaaattag gttttttaac tggatggatg caaattgtat tattttatcc agggatgatg
      901 gcagcattag gtgttatatt tggagaacaa gcatcagcac taattggtag tccatcactt
      961 ttacttccaa tagcaattgg aattatagta atagttgcag ggcttaatat gttaggttca
     1021 aaaactggag gagtcataca aactgtttct acaatttgta agttaatacc acttatttta
     1081 ataatggttg ttggatttat taaaggtggt ggaaataatc caatacttac acctatggtt
     1141 ggtgaaggat taagcctggg tagtgtacta ggtcaagttt taattgctat attatttgct
     1201 tttgatggat ggatgaatgt tggtacttta gctggagaaa tgaagaatcc tggaaaagac
     1261 cttccaaaag ctataatagg tggattatca gttgttatgg ctgtttattt tataataaat
     1321 ttagcgtatc tttgggtatt accagctaat gaattagcaa attatgcttc tcctgcatca
     1381 gcagttgctg aagttatatt tggttcaatg ggtggaaaaa taatatctgt aggtatatta
     1441 atttcagtgt ttggagcatt aaatggattt ttactaactg gttcaagggt ggcatatact
     1501 ttagctacag ataagacttt accaaagtat ggtatatttt ctaaattaaa ttctgctcaa
     1561 gttccagcaa atgcaatagc attagtatct gttattgcat ctatatatgc tttgtcaggt
     1621 caatttaatt tattaactga cttagctgta tttgctactt ggatattcta tgtattaact
     1681 tttatagggg ttatgaaact tagaaagact catccaaata taccaagaga gtataaagtt
     1741 ccattatatc ctattgttcc tataatagct atagcaagtg gtatatttgt tgtagttaat
     1801 caattgtgtt ttgcaggtat gaaaactact atgatatcta taggaggtct tgtaataaca
     1861 gctataggct taccagtgta tgcttatatg actagaggag taaaaagata aaccaagtag
     1921 tttacaaatg cttcataatt aaaataaaag agactgtctc aaatagagat aagtctcttt
     1981 tttattgtta aaattgtaaa gatatgttta attttacaaa aaaagagcgt tccatgaact
     2041 aaaaagttta ttttaaggta ttcattttat ttttagtttt ttgattataa aattaaacat
     2101 ctaaaaaatt atttatttta aaatacttta ttttaaagtg ttttttatca aactaagtgg
     2161 tatctgtaca acaaatatta tacatagctt ttatgaaaat taaatctttc tgttatatat
     2221 aatagaatat tgtattatat agaaaatatt acctgattaa tatagtgatt tataaatgag
     2281 attagaaaat tttatttgat aacaaaaatt agataatatg aatatataat gtatgtatta
     2341 aaaatgtggc aaatagttgt tttgctattt attatttgtt taatatttct aatttataaa
     2401 aaaaaaatta taaattttaa aaattataaa tgacatttta actagaatta attgtaaaaa
     2461 acactatata atactcaatt ttcaacattc tatacaatta tacagaaatt atacagcata
     2521 ataatgaccg aaataacaaa ttttaaaaat taagcaaaac tttttgtcga agttcaacgt
     2581 ctatatatat gtagtgtaaa tttttgggat aaaatactac aaaaatataa atgtaaaaat
     2641 atagtaatat tggaggtcga acgatgagaa ataaaaagaa aaaaataaat agaaagaagt
     2701 tgtatttgct tttaagtgct attgtagtgt gtctggcttt tatagtagtt ggtgttcgcg
     2761 tcagctcttt aaatatgaag gaaaatgaaa ttagtagaaa tgcaaaactg tcaagttcta
     2821 ctattacaga tatagtatct aatacatcaa tagaagttag taaagggcca agtaaaagtt
     2881 ctggaaaaat agcatacata actatagatg atggtccatc taaatttact gacgagatga
     2941 taaaaacttt aaataaatac aatgttaaag caactttttt tatgatagat gggaatatga
     3001 aggaatatcc acagcaagtt aaaaatataa ttaaaaatgg gaacacagca ggttttcata
     3061 gtgtatcaca tgatattcac aagctttatg ttactagtac atcagcaaaa gaggaatttg
     3121 atacaaatga tcaaactttt tataagataa ctggtaaaca ttcaaaagta ataagaatac
     3181 cttatggaag caaaccatat acaccacaag cctcttatca ggctttagtt gatgctggat
     3241 ataaaatttg ggactgggac ttagatacag aagactggag atctaattct tctcaaattg
     3301 tacaaaatgt aaaaaatcat attaagaata gaaaaggtga agataaagac caacttgtag
     3361 ttttaatgca tgagaaaaaa cagagtgcag aagctttaga ttcagtttta aaattcttat
     3421 cagatgaagg ttatgaattt gcgccagtag atcaaaacca aataccaaaa aattattggt
     3481 tacgtaattt agagtagtta aaatataaga atattgattg atatttttag aaattgagaa
     3541 taaaaatgag tgaggtgtag gtatattgaa taaaaaaatt tatataggaa tggtcggaat
     3601 attgtctttg atgatggttg gttgtaataa aagtttagca aaagtaaatg atgtggaaat
     3661 cacaaaagaa cagtacaaaa aaacaaaagc agttttatct gctactaata attatataaa
     3721 tgggcagtct ttagatgaat tagaaaaaac tttggataaa aaaggtagaa ataaattaga
     3781 aaatgttata atatcgttta tggtggataa tgaactttta tatcaagagg ctaaggataa
     3841 aggactaact ccaagtaaaa gtgaagtaga ctcaaaatat caagaactag aagataagat
     3901 gaatttgaat acaagctata aggaaaaaat ggacaaagca ggtgttgata aagattattt
     3961 aaaacaagaa atatctagag atttagcaat agataaaaat aaaaaggcct ttgaagatag
     4021 aataaacata agtgataatg atatggaagc ctactataca agtcataaaa aagattttaa
     4081 tgtagaagaa gtaagtgctt ctcagatact tatatcgact ttagataaaa ataaaaaaga
     4141 agtaagcaaa gataaaaaag aagctttgaa gaagaaggca gataatatat tgactaaaat
     4201 caaaaatgga gaaagttttg aaagtttggc taaaaaatat tcggatgata aagcaactgg
     4261 aaaaaatgga ggacagctag gatattttac aaaggatgat aaaaatgctg agtttacaaa
     4321 ggaagtgttc aaattaaaga aaaatgaagt ttcaaatgtg tttgaaacta gttatggata
     4381 tcatatagtc aaagttactg ataaaagaga aagacaaaaa agttttaatg agtgtcagag
     4441 tttaataaga gaatctattt taaatgaaaa gtatattgag catataaaaa aactgaatga
     4501 agatgctaaa atagacagat agaatttcta acagctcaat cctagcctgt aatcggaggg
     4561 agattttaca ggaatgttta agagtttaaa gagaacgaaa gttgagaaat acattatcga
     4621 taataaagac tctttttata gaatagcata tagttatacg aagaatgaag aagatgcctt
     4681 agatgtggtt caagaagcca tgtataaggc actatactca gtggaaaata ttaaagaagt
     4741 aaattatata aagacatggt tttataaaat tttagttaga acgagtatag attttattag
     4801 aaaaaaccgt aaatataata atatgacaga tattgacctt atagatgaga ctggagagta
     4861 tgataaatat actgatttgg atttaagaag agctttggaa gaattaccta ttgaatacaa
     4921 atctattata atattaagat tttttgaaga tttaaagatt gaagaagtag caataatatt
     4981 ggatgaaaat gtgaatactg ttaaaactag gttatatact gctttaaaaa aactaaaatt
     5041 aaaaattgaa gagtagggat aaaaagaatg acaagcaaag aaaggttaaa taagttaaaa
     5101 gatgagtatc ataaaattcc aatacccaag aaattagata ctataataaa tcatgaaaaa
     5161 atagaaaaca tatatcgaga gaaaaataaa aaagtaaata gattaagatt taaagttgca
     5221 atagcctttg catgtatatt tacagtatta gtaaatataa gtcctgtatt tgcagacaat
     5281 ttttctaaga tacctgtaat tggagcaata gtagaagtaa taactataaa aaattatagt
     5341 ttaaaaagtg aaaattatga agctgagatt gatattccta aaatacgagg tttaaaagat
     5401 aaaaacttag aacaaagatt aaacagtagt tttatggaag atggaaaaag gctttatcat
     5461 caattccaag agagaatgga gaagatacaa tcatcaaaga ataaaggata taaatcttta
     5521 agtttgagtt atagtgtaaa aaataattct aaaaaatttc tatcaataga gatgacaaaa
     5581 aatgagatag aggcttcatc atatgtgagt aaggtacatt atactattga taaaaaaaga
     5641 caaatagttt tgactttgcc aatgcttttt aaagatgata agtatataaa agttataagt
     5701 gataatataa aagaacaaat gagagaacaa atgaaaaagg atagtacaaa atcctatttt
     5761 atagatcaaa aaaaagactt gcctgttgaa gattttaaaa caattaataa gtatcaggat
     5821 ttttatttta ataaaaatga agaccttgta atttgttttg atgaatatga agtagcacct
     5881 ggttatatgg gcgcagttga gtttgtaata ccatataaag taataaaaga tttgtaaatt
     5941 gaatagtagt ttatatataa atcttttaag gaggacaata tgactacata taaaaaactt
     6001 aaaaaatcta tatttaaaat tgctatattt tcaatatgct tattagtttc attagtagat
     6061 acaaacccta tatttgcagg tagttccttt aatgaaactt caaatagtga tacgataaag
     6121 gtgttaaatg ctaagagtat caactttaaa caagacaatt atgaagtgaa tgtgagtatt
     6181 cctaaaataa aaggtttaaa agataaaact ttagagaata aattaaacaa tgagcttttg
     6241 caagatggga aaaaaattta cagtgaattt caaaataaaa tgaaaaagga aaataataag
     6301 ggtcatagat acctaaatgt aatccataat gtcaaaaata attctaagga ctttttatca
     6361 atagaaatga caaaagaaga gatagaagct tcctcatcta taactaagaa gcattacact
     6421 gttgataaaa atagaggaat actattaaat ttaccaatat tttttaaaga tagtagatat
     6481 attagagcta taagtgataa tataaaagag cagatgagaa atcaaattaa gaaagatgat
     6541 acaaaatctt attttataga ccaagataaa gactcgccag tgaaagattt tgaatctata
     6601 aataagtatc aagattttta ttttaataaa aatggaaatc ttgtgattag ttttgatgaa
     6661 tatgaagtag ctcctggtta tatgggagca gtagaatttg tgataccaaa taaagtaata
     6721 aaaagactaa gatagatata tagaagattt ttagatagac tggtaaggag aattatatga
     6781 atatatatga acaagcaata agattaatag aaaataatga ggatttcgca tttgctacaa
     6841 taacgtctca ttcaggttca acaccacgtg aaactggagc aatgatgatt gtgaaaaatg
     6901 attctactat atttggctca gtaggaggag gtagtgtaga agcagaatgt ataaaacatg
     6961 caattaatgt tataaaaaac agagaatcaa tgttgtataa atttactcta aacaaatctg
     7021 atgtggcaaa actaggaatg atatgtggag gtactggaga aatacaaata gattttatag
     7081 atagtaaatt aaaaagtaat atagaaaaat ttaataagag actaaaggaa aatacaagta
     7141 aagcatatat atttggtgca ggtcatattt caagagatgt tgctgtgata ctatctcttt
     7201 tagaatttag aacagtagta atagatgata gagaagaatt tgctaatcat gaaaggtttc
     7261 cagaatcaga agtagtagtt ttagattctt ttgaaaacat accagatttt ccaactgacg
     7321 aaaatagtta tataattatt ttaacaagag gtcatctata tgattcaagt gctttagaat
     7381 gggctcttaa aagagaggct ggttatatag gtatgattgg aagtggaaca aaaattggat
     7441 tgacttacga aaaactcatg aaaaaaggtt ttaagaagga agaattatca aaagtacatg
     7501 caccaatagg cataaaattg aatgctcaaa caccagctga aatagctgta tgtatagctg
     7561 ctgaacttat aaattgtaga gctaataagg aaaaataaac taatgaacac agggagtaaa
     7621 gatattgata ctttaaaggt taattttaga gggattgaaa taaaagcagt tttagtatat
     7681 aaaaatagaa aaaatatttc tataaaaata gatccatttg gcaaaataac tgtaatgagt
     7741 cctcctaaaa tatccaaaaa aataataaaa gatataatta ttgaaaaagg agactggata
     7801 cttaaaaagt cagaaaaatg taaaggaaga gaggaagtat ataaacaaag aatgtttata
     7861 actggcgaaa aatttcttta tttaggtgaa gagtaccatc tagttataaa agaactgttg
     7921 agagattctg tcaaaaaaag taactgtaga ataactatta acgaatatca aatagttgtt
     7981 cagacaaatg atacaagtac agattttatt aaaaaatctt taaaatcttg gtataagatg
     8041 gaaagtgaaa gaatagtatt agagagaata gattttctta aattaaattg tgaaataatg
     8101 aagcaattag ttccagcgag tgttaaggta aaagaacaaa ataagagatg gggaagttgt
     8161 acagctcaaa aaaatattta tataaactca aaaatatcta tggcaagatt agatgtaatt
     8221 gattatgtaa taatacatga gtttagccat ttagtacata tgaatcactc taaaaaattc
     8281 tatgatttag taaaatccat tatgcccgat tataaagata aagaaaattg gctaaaaata
     8341 aatggatata aaataataat ctaaaaacga ttattccaaa atataggcgt aaagtataaa
     8401 agaagtatta ttgtgaaaaa aataaataat ctgaaaattt taaaaaaagt cattgacatt
     8461 gtaaatgata gggaatataa tctatattaa caacaaaaca gaattaaaat ataaaattaa
     8521 aaaattaaaa gcaatgacag agacaacaat actaatagtg ttatccacag agaaccaatg
     8581 ttgctgagaa ttggtgttaa cagtagtata atgatcactc tggagctttt gtactgaata
     8641 tttttagtaa gtacaaacgt atgtcagcgt tacatgacta aggttaaggt aattaattac
     8701 ccgacctgaa aaaagagggg tagatgtatt ttttatatct acaaataagg tggtaccgcg
     8761 gaatataact ttcgtcctta taagtaatat ttatattgct tataaagatg aaagtttttt
     8821 tattttaagc gatataaata aatttaatcc atataaaatt aataaaaaaa taataaaaat
     8881 aaggagggat ttttatggaa aatactgtat atgctaaatt aaaccaagga atagattctt
     8941 ttttaagagt ggctatgact ctaagaagaa gagaggttga tatacaatca ataagtatga
     9001 ctgtagataa tatgaataat tcaggtataa aattaatagt aaatgaagaa aagacatctt
     9061 tagattctgt cttaaaccat atgaaaaaac tacatgatat aagagagata actgttgaaa
     9121 gaatgagaca ttaattaaat atattttata aaactaaaga taaatatgct tattttatta
     9181 aaaaaactta ctaaatttct gattatcttt tcataagttg gtaaatgccg atatatcccg
     9241 tattttaggg ctttatcggt attttctttt cggaagatac cttgcataag ctggcattta
     9301 ccagcatgaa aatgcaacca aaagtagtaa atgagtagta aatataagct ccgatattaa
     9361 caagccagtc tttccagttc tgcttttgca gattgaaatg taccgtgtgc gtaatagcca
     9421 agtgtcatgg ttatgttagc gtgtcccatg aggtattgca gagtgtttgg gttcattcct
     9481 ctgtttgcca tattcgtaca ataagtatgt ctgaatgaat gtggcgtgat gttcggtaac
     9541 ttgtccgtgt gatacttgtt atacttctta atcagtcctc gcaccatgcc ctcatagttt
     9601 cctgcaactt taggcaagcc ctcacgattt aggaatagga aattgctgta accacctaca
     9661 atcagcggtt gtgcctttcc tctgttcttt agtattcttt ggattgcttg ataagcccgt
     9721 tctgtcaatg gaagttcccg ttttccgttt ttggtctttg gcgtttcaat atagtaaccc
     9781 atttcgctat ctttcaataa ctggtggtct atattgagta ctctgttctg catatcaata
     9841 tgcgtcgtca gtccgcaaaa ttcagaaata cgaagtcccg tttccagcag aagcacaacc
     9901 tcatcataat acttactata aattttgtcc ttttccataa aggcaagcag gcgttcttcc
     9961 tgctctggtg taaggataac tttctgttcg gtatcatctt ccagaacatc acttagctta
    10021 aattcaaatg ggttctttct gatacagtcg tcttgtatcg ccatgtaaaa tgacgctttc
    10081 aaggaacgct tatagttatc aatcgtttta taggcatatc ctttttcact cattctaata
    10141 gcccattctt tagcgtccga ctgcttaacc gtatcaatcg ccctcatacc caatgggtca
    10201 tttttcagag cgttcataag atactgtcgt cctttttcag tagccctttt gatgttcttt
    10261 ctttggctgt tcttcttgtc gtagagctgg cagactgtca ttttaccgcc gactgtgtcg
    10321 ataccgtcgt taaggtcttt ttttatctgt gcttcttttt ccctcaacga tatatcatca
    10381 cgctttccag caggtgtctt gtctgtcggt acaagtttcc aagaatagat aaattgtggc
    10441 tttccgtata tatcggtata tttataaacg tatcttccgt cttttcgctg gctctctcca
    10501 ttacgcaaat tgcgattttt actgtctttt cgtttcacat tagacatagt gtaaagctcc
    10561 tttccgtcat ggaatgagcc gtgatacgct ataccttatt ataccatatc tacggctcaa
    10621 tgacattaga tttcgtccaa tgtatctatg attttttcaa attgttttcg cttaatctga
    10681 atacgattac cgttcacgat aacccagcca gcgtcaagat tttcttcggc taatttacgc
    10741 aatttctttt cgccaatacg gaagtattta gacgcttctt caatcgtcag cgtatatttt
    10801 tcccagatag gcacatcagt attgttcata atctatacac cccctttact gtgtgtcgtt
    10861 ttttacaagc aggcagacgg ctttggaaag ctccgttagt atctcaacta ttcccattct
    10921 tgtgggcaga accgcaccat gcggacgtat cattattctg tgaggatagg tcgtggcaaa
    10981 acgacttttc caacagtcgc tctcggatca ctgcgtgggt cgctcgcttt ctttttgaaa
    11041 aggtcgtggc gtacagtccc cgtggctcgc tatctcacaa acgtatctgt ctgctttatt
    11101 cagttgtcaa agagctgtgg cgaaagcgtg ttgctttcat gtaaaagcag gagcagagca
    11161 ggaaagaggg gattgaacaa atcatgctct gcggttactg cttcttattc ttcggtttct
    11221 aaaggaatat caaagtccaa catcattttg ataagtgctt ctctgatacg tccctttaat
    11281 tccatgtcta cgactatgca gacattacca tatctgtcat agaatggacg taaacaacat
    11341 tttgatatgt acgggtcata aaatgccagt atcttttcaa tcgaatttac gttgccgtcc
    11401 acagccgacg agataaggta aaatgacggg cgtgtgttat tcatcattca tgttctcctt
    11461 taactttttc ttgatttctt caagtgagtt cttcctactg cggaacgacg ttgaacggtt
    11521 aatctttaat ctgtcgccga tttctgtatc gctcatgcct aagaagaagt acatcaacaa
    11581 gatttctctg tccttttcag acagatactt aatcgcttct gctaaatcat catcaaggac
    11641 acgaacctca ataccgcata catcaaaggc ggtataatcg ctttcatatt cgtcccagac
    11701 agccagcttt tccacgacga tttctggaag ttcacaatag gaaatttcct tatttcttcg
    11761 tcgctttaat tctttgcggt aattacggac aatgcccttt actacacgtt tgagcttgca
    11821 atcgaattga cattgtatcg ttctttggaa gttcgacggt ttcatatcat cacaccccct
    11881 ttccgttatg acgtgaaaag tgtttatccc tctttccgca ccatatctgt acggcaaggt
    11941 gtgatttgtt gcaggaattt gaaaaaaatt gaaaaaattt tttcgggtac aaaaaaagcc
    12001 cgcacaaaac atatagtttt atacgagcta ttaaagctgt aaaatattca gtttttaata
    12061 aaatgctatt aggtagtgta tgattgtata gaatttcgct taaaatgttc cataatacaa
    12121 tcccccttac agcacttgtt ttgtattaca cttttgtctt ttgggtaatc ttgtaaatat
    12181 attcttctga tgtagggcgt ttatttccaa aatacttttt aaaatttgcc tgcacctctg
    12241 ggtcggtgct gttcatagct tcatcaatcg ttgcttcaat atccgcccga acatcagaca
    12301 atgatacacc gccagctttt gccccagctt tcaatgcttt tttaatatct cgttttttca
    12361 gaccaatcat atgtgtgttt ctcctttaag cataaacatc ttgaaaagca agttatgata
    12421 ttgtaaatca ttgaaaattt aatgtttctg ctcttataat actatttttc tattctatat
    12481 cagtttttct atacgattat acagaccacc ccagactttc ttgttgaata gaatataatt
    12541 tgtgatatag cccttttctt tccataagct cattatgtgt tccatgttca actatttttc
    12601 cattttccat tactaatatc tggtctgcat ctaccacagt ccttagacgg tgtgcaatca
    12661 tacagctcac ggcccagccg ttgattgttc tggctgtaac tttccgattg gccccgtgtg
    12721 cggccatccg tctgcatgga gatcgtagcc ttgcccagcc agttctcgga tatttccttg
    12781 atggtgctgg actcccggcc gccgagaaaa atcacgctgt ccatatttcc caaaatcgtt
    12841 tcagcgtgct tatcataaat ggccttgcat tgggccaact gttgatacag gagaaccaag
    12901 gacacttccc gagaacggat cacagccacc agcttttcca gccccggcac ctgtcccgtg
    12961 ttggccgcct catcccaaag tacccgcaca tgatggggca ggcggcctcc gtgaacatta
    13021 tccgcccgtt cacacaagag gttgaacatt tgggaaaaag ccagagccac caaaaaattg
    13081 taggtgctgt ccgtatcgct gatgcagaaa aaggttgccg tgcgcctgtc gcccatgcgg
    13141 tcaagctcca gctcgtcata ggacataatt tcccggagct gggggatgtc aaagggggcc
    13201 agccgagcgc cgcaagagat caaaatactt ttggccgttt ttccgctgct caacttgtac
    13261 tttttgtact gctttacggc gaagcaatcg ggcttgcgct gctccagccc cttgaacata
    13321 tagtccacgg cgttgaggaa gtcctcgtca tcctccttga cctccatgct ggagatcata
    13381 tccaccagcg tgttcatatt gcgctcctcc tcggccccct caaaaatgat gtaccccagc
    13441 agagcgcaat acagcagcgt ttcggccttc gtccaaaacg gatcgccctc tttgccctcg
    13501 cccttggtgt tggagatcag cgcattgaca aactttagaa tgtcggcctc gtttttgatg
    13561 taggccagcg ggttatagtg catggatttt gaaaaatcaa tgctgttgaa taccttaatc
    13621 ttgtacccac gcccttgtag aaaagaacca acttgggaca agacgctgga ttttgggtct
    13681 acacagacat acgaggaatg ggcttgaaga agctggggcg taagccagaa gcgggtcttg
    13741 ccggagccgg acgatccgat gatacaggcg ttgaggttgc gggcgttggc tggattttta
    13801 ggccgggtgt tcatggtgag ccgttctgtg cctgtaagaa tcacattgtt ttcaaacttt
    13861 ggatcggcaa aaggctggat gtctttgggg cagccccaac gagaactacc gtattcttca
    13921 tcccggcgat attttttggc gttcttgctt ttgaagtaga tcagcagccg aaaggccacg
    13981 gcacccacaa taccaatgag ccagtctgcc gggttaagcc ccggcgagaa gtccgaaaaa
    14041 gccacgctga tggtctgcat cagccccagc agcttttccc cgaagtttgc gccagcggcc
    14101 agacggtagg ccgtacccat tttcaagcag gcccagccga tgaacagata cgggatattg
    14161 gggaggacat attttcggat cttatctgtc ggcatgggac acctcctgta cccgctcttt
    14221 gggccggggc tgctcacggg agagctgctc cgacgcccgt ttgagctgat cccggattgg
    14281 gatgcgccgg gacttggttt tgttcagtac cttgcgggaa tattcagaaa gacaggcgct
    14341 catggcgtca gcctgtccag acttgaagaa cagcagatac ttgtccggcc cggttttaaa
    14401 aaaggcgtag tctacattcc acttccgggc cacccggtca aacagcttgg tatcgccaga
    14461 cagctcaatg ctgttggccg ccgtaccgtg tgccatgagc tttttcacgc tctgtctgcc
    14521 gtggggcgtt tgggccttgc ggtgttcctt ggcgattttg cggccaacgg cccggagtgc
    14581 ataggccagc ccccgggcgg tcagcttgga tgcccgcatg gaaatagcga ttgtgcgccg
    14641 ggaaatatct tcatctacca ataacagcac cctcctttct gccaccttgg gacaacttgt
    14701 cccaaggtgg cgttatcgct ccgcatgggc agggccgatg taatgtttac ctgcgtccag
    14761 agcggagcgg tcaattacct ccttataggc cgccatctgc tcccggatat tcagcttggg
    14821 ataggaaaaa atgcggtgtt catcggggat gtcctcccgc ccggaatagt gttcaatgaa
    14881 gcggctgcgg ttgttcatca catagccgcc gggggcgtag tgtccgtcct cgttgatccg
    14941 cacatcccgg ccatagccgg aatagtcgat gtagtcgatc agatgctcgg ggatttgcag
    15001 ggcttcaaag tcttggatat acatccggcc caattcctcg tcatcccgta ccccgctgta
    15061 aaactcaaaa cagtcgaggt tttgggtcag attgattaaa tccttgacgg tgccgctgta
    15121 ctcgccgctg tccaccacag cctcaaactt ctccagatcg ctgctgtcca tttccgacaa
    15181 cagggcggcc agatagttga gttcgtccaa gttctcatac tcgcccaagt gatcgcacag
    15241 gcccagcaca tcgctgtcaa agctggtaat gaatatctct ccatagcgga taccgtcaac
    15301 gccgatccgc ttcaagagtg cctggacttc ctccggcgtg gtgggaaact tcaatgtttc
    15361 acccacaagc tgcccctcca catatttgcc gaggttggta atgtaggctt ccagcgtgga
    15421 tgtcatatca gcggcggccc tgccccttga cggtgaggat gccctccaag gtggtggcgg
    15481 tgatccccag ccgctgggcc acggcgatgt catttttcat ggcctcggtc acggtgctgc
    15541 cgcagactac cagcacatgg gagcaccgaa gcaggtcacg gcccatgtcg atgccgctct
    15601 tatgctcctc ggggatagcg tcattgagaa acagcgggtg atacaggggc gggcagatgg
    15661 gagagaatcc cgcatcgtac acgaagcggc aatactgcgc cgcttgcttg gcgttctcac
    15721 aatcgctgcc gcaccatgcg gcggtgatat aggcaagggg tcttttcatt ttgaaatcct
    15781 ccgtttctgt atggtaggtg ggtcaacctt ttccccccgc ccttttccag tcttggaaaa
    15841 gggggcggct ctggaggata tacccccgtc acgcctccgg aaatagcaca gccggggcca
    15901 gccgtaaagg gcaagccgcc cttggcggtg ctgacgcacc cttgacggcc agcgcccgac
    15961 tatgccgcaa tacgggcggc gacgggggat aaatccaaag agcctcgtgt gaggggacga
    16021 aaaagacctc gggacaagtt gtcccaaggt cggttacttc tccatatcct ttttcttgtc
    16081 gggcttaccc agctcggggg gctgcttggc cttccagtca tccagcaggg agatgatctt
    16141 gtccttcatc tcacgggggg acttgtcctt gccgaaatac ttttccagtt ccacgctgtt
    16201 gataatcacc ttgtctacct cctttttctg ctcactcaaa ataccgtcaa tgacatcgcc
    16261 gttgagcgcc ccctgtttat ccaactcccg cagtttctgc gcttgggaca gggacggaga
    16321 ggactgctgc ccctcaatgg caacggcgat ataccgctga tgcttgggac ggataaagga
    16381 aatctccacg gcaggggtaa acgccaactg cttttcgtcc agcattttct tcaaatccgg
    16441 gacgagttca gtcaagcgga tataccgctg cacctgctta tagttcatgc cgttgcgatc
    16501 cccgacaacc tgcgtggagc gctttccggc gtccttatcg tcctcaccgg gccgagcgcc
    16561 ctggtgcttg atagcctcca cctgctgctt caacgctttg gctttctccg tgggcaaaat
    16621 cttctcacgg tggcgcaggt tgtcatcagt catggcgagg atggcctcgt catccgtcat
    16681 tttgcggacg atacagggca tattggaaaa tccggccagc tcgctggccc gctggcggcg
    16741 gtgtccggcg atgatctcat agccgccgcc ctcacgggga cgcaccagcg caggctgatt
    16801 aacgccagcc gccttgacag actccaccaa cccctgcatt tccgcatcgt cacggacgcc
    16861 aaaggggtgg tcttggaatg ggtgcagctc cgaaagattg agatatacga tctcctcttt
    16921 ttcggctcgg gtagcgtcac ggggctgggc gggctgctct ggctcggcag gagcggcggc
    16981 ctcctccttg ggggtgggag ccttactttg ggacattttg tcccgcttgg gcttttcggc
    17041 cttggtggga gtggccttgt ctttcttggc cggatcagcc ttgctggggg ccgccttgtc
    17101 agccttggac gggcggccac ggcggggctg ctccggcttt ttgtgttcct tatcgggagg
    17161 gtcaacctct tttgccgggg gtgtagcctt accagtctcc tcacgggcgg cggcaaaatc
    17221 caccacctta ccgggggtgg aggcctgctg ttccggctta tccggctcag gctgctccgg
    17281 gattgtcacg ccgggaaact ccggcgcatc cgggatggcc tcgcccattt caaagagggc
    17341 ggcctgtccc tcatgctcca aaatgagctg ttcctccacg gtcagcgcct ctggcccctg
    17401 cggggcgggg gcggcggtgt cggccagatc gggaacgggg ctgggctgct ccggggcctc
    17461 ggtgggaata cccgcctcgt ggctaatggt ctttttatct tctgccactt aaaaacctcc
    17521 tttgtcgtga aatgaaaaaa gccagcccga tggctggccc gtggggatgt ccccctcctt
    17581 tcagttttct atatgaaaac gccgcccgtt gtcctgttgg gcggcgtaat tcgcaaaatt
    17641 aaatttttct aactaaaaaa tgatgtagtt agctcttgct aacatacatc attttacttt
    17701 ttatatttat ttgcttctac tccatagcta tatatctatc caaaaaatag cccaaaagtg
    17761 ttaattttct gcctttcgat aatctttagg taaaatacca tataccgatt gaaatgcaat
    17821 agaaaattta cttgcattac tatatccaag acttaacgca atatcattta ttttacgctt
    17881 tgaatttctt aattcattag acgctatatt catcttgtat ttttttatgt aagaataagg
    17941 agtatctcca tatacttgtg caaagacttt atacagtaac gacaagttaa ttcctttttc
    18001 ataagctaat tgttccagag atactttttc ttctaaatgt tctgtcatat atttgcaaac
    18061 atcttttgtt atttgtatat attttttgtt gaaatatcga aattcagttt cttcattgcc
    18121 cgacagtttg ttgatgaaat ataaaaattc gattgcttta acacgaaaat aggtaatact
    18181 ttccttatct ttagcattat aaaattcttc aaaaagatgt cctaactcaa agtctgcatg
    18241 acttaaatat ccatttttat ttaactttaa tctttcactt attttgtcca tatctaagca
    18301 aaaatcattt agaatttttt gtgtatctgc actaagggcg tgtttatcta tgactaagct
    18361 aaatgcgtaa cattttttta ggggaaagga aaaagatata ggcaaatgtt tagtccccat
    18421 aatactgaaa tatccttctg acaaataaaa catctgatga ttagaaaatt cacattcata
    18481 acgccccgct tgacaatgga caatagaaat tatatcagga ttaaattttt gtgagggcat
    18541 aatttcatct gtataaaaat caagaaaaca aagtgtgata ccgtcataaa gattataact
    18601 tgtaataata ccttttcctt tacagccata atctataata acacaatcat tatcactatc
    18661 gactaattgt gctttatctc cataccaaga tttattaaat ctattatcca taccaatcat
    18721 ctctttttgt taatctattc taattttaat attaacatat atctgaaacg tgagcaacgt
    18781 tttctgcttt tagggtaaag ggggctatct ttttttgata accccttaat acttatccta
    18841 taatcttcca gttgctatcc ttatgtagca caagctcata ttgcgatacc tgcgttgcct
    18901 ttgtctgatt atcaaggaat ttcacagcaa ccttgacttt cacattctcc ccgtcctttg
    18961 taaagatagg gtttatcagt tcagaataaa ggtaatctct gccgataggt tcaagtacat
    19021 taccagatac ataataggca agttcttttt ctgtggctgt tgggtacagc ttaaagaatg
    19081 tttccagaaa tgcggtagcg tcgtttacag tatcagcgtc tacacttgcg tctgcttctg
    19141 gtgtcttagg ctcatagtct gatttttcga ttgctggtgc aagggtaggg ttctgaacga
    19201 ttaccatatc cccgtcagcg tctatatgga cttttacggt ataggttgct ttcacattgc
    19261 ttgtcttttc tccctctttt atctgctgat ctacttcgta ggtagcagaa aaagtgttcg
    19321 ttcccgattg ttcgatactc catacaatca catttgtagc tgtggagctg gtcggtatat
    19381 ccgttctgat tgtatcaaca ttcaagtcct gcaattcctt tgtcagataa ccgctgattg
    19441 cctgcgtcct tgcttcgata gcttctttgc tgttattcca tgtgtagtag gacttcgcaa
    19501 aattcttcac gaaattttct atcccgttgg tgtcctgcaa gcaaagttca atgatttctt
    19561 tttcatgggt cgtgtgctgg tcgatagcag taaaattctt atacactcca aagctcacgc
    19621 ttgcgataag caccacccac aacgcaatca cggttttctt atgtgtgcct accttaacag
    19681 tacgcacctt tttttctttt ggttctttga tagtttctgt ctgtttctta ttcttcttaa
    19741 acatattttt caagtccttt ctattgtttt actcgtcctg caccgattaa gtgctgttgc
    19801 cagtaactat tacttaggtc tgcatatcct atcgggt
//
LOCUS       DAEOTL010000077        19714 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEOTL010000077 DAEOTL010000000
VERSION     DAEOTL010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19714
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.077"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            48..917
                     /locus_tag="KRH82_003022"
     CDS             48..917
                     /locus_tag="KRH82_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBG8656288.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITSEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            1721..2428
                     /locus_tag="KRH82_003023"
     CDS             1721..2428
                     /locus_tag="KRH82_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBG8656289.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3040..3540
                     /locus_tag="KRH82_003024"
     CDS             3040..3540
                     /locus_tag="KRH82_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656290.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3790..4569)
                     /locus_tag="KRH82_003025"
     CDS             complement(3790..4569)
                     /locus_tag="KRH82_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656291.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANDVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4566..5045)
                     /locus_tag="KRH82_003026"
     CDS             complement(4566..5045)
                     /locus_tag="KRH82_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656292.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAINNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            5854..6555
                     /locus_tag="KRH82_003027"
     CDS             5854..6555
                     /locus_tag="KRH82_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBG8656293.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            6581..7237
                     /locus_tag="KRH82_003028"
     CDS             6581..7237
                     /locus_tag="KRH82_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656294.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            7342..8982
                     /locus_tag="KRH82_003029"
     CDS             7342..8982
                     /locus_tag="KRH82_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBG8656295.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHVSHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            9340..10662
                     /locus_tag="KRH82_003030"
     CDS             9340..10662
                     /locus_tag="KRH82_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656296.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIGTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            10859..11866
                     /locus_tag="KRH82_003031"
     CDS             10859..11866
                     /locus_tag="KRH82_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBG8656297.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            11904..13316
                     /locus_tag="KRH82_003032"
     CDS             11904..13316
                     /locus_tag="KRH82_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBG8656298.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTKKNKKVIF
                     KGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKIT
                     HNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIL
                     SNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDN
                     LWIVTQLGLNPQEVAKGMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEM
                     MLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYE
                     VERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKE
                     EWITFDGMDVLKQMYMGVEE"
     gene            13458..14723
                     /locus_tag="KRH82_003033"
     CDS             13458..14723
                     /locus_tag="KRH82_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8656299.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            14765..16363
                     /locus_tag="KRH82_003034"
     CDS             14765..16363
                     /locus_tag="KRH82_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBG8656300.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            16398..17420
                     /locus_tag="KRH82_003035"
     CDS             16398..17420
                     /locus_tag="KRH82_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBG8656301.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(17903..19306)
                     /locus_tag="KRH82_003036"
     CDS             complement(17903..19306)
                     /locus_tag="KRH82_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8656302.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
BASE COUNT         7114 a         2245 c         3482 g         6873 t
ORIGIN      
        1 tgaaatttct atattaatat gtagtaattc aatattatta taaaggagtg gttattatta
       61 aggcaattga actttataaa aaattagatt tagaatttaa tattaaaaat attaatgatg
      121 attggagttt tatgaatttt gaaaatgatt ttatcacttc agaatttaga aaaaaataca
      181 taggattagt attagataat gctcaaaata ttaataaagt atacacaact acttttcctg
      241 ataaagaaat aattaagcag gttatagata aagatgaaaa agatatttta attttttcac
      301 atcatgcaat gggatacata gcatcagatg aaggttttcc atttcacgac ataccactat
      361 cttatatgga agagatgaaa aatcgtagaa tttcttttta tgtattacat tctccactag
      421 acaactatag tgactattca acttctgtta gttttgcaaa agctatgggt ttagaaatag
      481 tcaaaccatt ttgtaaatat gacgataaaa ttgaggtagg agttatatgt aaaacatcac
      541 taaaatcaat agaagagatt aaggaattaa ttaaaaaatc tgttggtcat gatgtgaaat
      601 tgtatgatta tggagattct gtattaaaag atggtttagt tgctattgca gcagggggag
      661 gaagttatcc atttgtagca agagaagttg ctgaacttgg tataaatcta tatattactg
      721 ggtttactaa gcctttaaaa cattttgaac cagtattaga gtttcatcaa atagcaaaag
      781 ataatttaat taatgttata ggtgctactc attattctac agaaaaattt gcgtgtatgg
      841 gcatggtcga ttattttaaa aatctaggtt tagaatcaga atttttgcaa ggaaaatatt
      901 acttagagga tttataggac atattaaaca ataaaaataa acagttagta aaaatttatt
      961 ttactaactg tttatttttt tacctattta tccagtgttt tgaaaaaatc tatctttatt
     1021 ttttaaacta agaaaataga cttttaattg ctgattagaa gatttagttt tgatgtcttt
     1081 taaattattt ttcgatattt tttagtttat tttttgatgt attttagatt attatttagg
     1141 attgattaga atttataaat atttatttta gattattata aatatttatt ttaaaaaaat
     1201 agaattatta tatttatgat aataaatggt ataataaaag gtaaagtgtc aaatatgcac
     1261 taaattaaat aagttaatta gtatataggt taaagtggaa gtaattaaaa cttattaagt
     1321 attagaaaat gacttcttat tagagtaagt atctaaaatg atataaaaat tatgattact
     1381 cattaaagtg actattatag agtggataag attactcatt aaagcgatta ctgtagagta
     1441 gataaaatta ctcactaaaa taactatcat agagtggata agattactca ttaaagcgat
     1501 tgctgtggag tagataaaat tacccatcaa agttaactat cacagtagat aagattattc
     1561 attaaagtta ctatcacaga gtggataaaa ttacacatta aaattgtctg ttaaagaatg
     1621 aataaaaaag agattgctca atataagaag catataaaaa ataaaaaatc aaacgtataa
     1681 aatttaataa ataataactg atagggaaag gaaagataga atgatattta caaaaagtaa
     1741 taaatacgat aaggactttc tcatgaaaaa tatgatggga cctaattgta taaaaatatt
     1801 ggaagaatta acaagtaaga taaaactaga aaagggaatg cgtattttag acttaggttg
     1861 tggtaagggt atatcttcga tatttttagc aaaggaattt gatgctactg tatttgcaac
     1921 agatttatgg atagaaccaa ctgaaaacta taaaagattt aaagagttta aattggatga
     1981 taaaatattt ccaatacagg cagaggcaca tgaactacct tatgcagaag gtttctttga
     2041 tgcggtgata agtatcgatt cttatcacta ctttggaaac aaagaaggat ttttagacaa
     2101 tcatatatca cctcttgtaa aagagggagg aatacttgct atggcaatgc ctggattaaa
     2161 agaagatttc gtggattgta taccagatga actcattcca ttttggcaag ataatatgaa
     2221 cttccattca attacatggt ggaataaact ttggtctgaa tcggagtctg tgattgtaga
     2281 gaaatgtgaa gctttaaatt gtcatgatga agcttggaag gattggataa attgtgataa
     2341 ttcatatgct ataaatgaca aaaaaatgat ggaagtagag aatggaaagt attttaatac
     2401 aatttctttg atagcgagaa ctaaataatt gtgatgaatt tataaaagta taagataagt
     2461 agaaatataa gttgaatgag agtataagaa gcatagaaat ataagttgaa ttaaagtaga
     2521 aggtaaataa aaatgtaagt taaataaaga gtttatacaa aaatgatttt ttagattatt
     2581 tatacccaat cgagttgctt aggtcagttg ggtattttta tttttttaaa gttaaattgc
     2641 aaatactatt gtgtgatata tattttaata ctaaatgttt gttttataag aaataaacta
     2701 atagaaaaaa tagctttaac aatgaaagca aaaaaggtat tgatgaagac taaaaatttt
     2761 atagtaccat tttatatatt tttttatata ttttattata ctttaaatca aatttcaaaa
     2821 tgattaagta tatatactca aaagattaaa gagctatatt tattatacta ttaaaaatta
     2881 ttttaataga gatacaagag atagatatat tggttttaat tttatagaaa tatacaaaga
     2941 tattttaagc taatatatag taatttatat agcattataa aatagaatca tataaaataa
     3001 gttaactaca atcaaaaatt aaaaagggga aatgttaagt tgatagaagg cataaaattt
     3061 ataaaggcag aagaaaagta tatttattcg tattggcaaa cttttgataa aatagcaaaa
     3121 gagaggaaat atctagctat ggatgaagcc tttccttttg aagaaacagt tgaatttata
     3181 aaaaatatta taaataaaaa cttaccacaa ctgtttataa ttgatttaga atcagataac
     3241 tgtattggtt ggtgtgacgt tttacctaaa actgaaaaag ttggttatct aggcatgggt
     3301 attcttaaag agtataggga aaaaggtatc ggaagtagtc ttttaaaaca aattattgat
     3361 ttatcaaaag aatatgggta tgaaaaaatt gagcttgatg tatttaaaag taatagtaga
     3421 gctattcatg tttataaatc tttagggttt gtagaggtaa atacaatatc tagtggtttt
     3481 acatggaatg atagacctgt aaaagaagaa gtaattcaaa tggagcttac acttatataa
     3541 aataaagtta aagtctttaa aattccatat acacttgtat aaaataaagt taaagccctt
     3601 aaaattccat ataaaagaaa tatttttaag ggctttttaa taatggttct tttgaaggta
     3661 gctaaatatc taaaatttta tatattaaat ttaaagaaaa tataaagatg gaagatacaa
     3721 ccatgtttac taataaaaaa attaaagtca taaataataa actcataaac aacttattat
     3781 tacttatgtt tattttgcat ctattacttc atgagccatt ttaactaagt cattcataga
     3841 taaatttgag tcttgaactg taaaagaata gtaaactcca tcttgtttcc atgtcaaaaa
     3901 cttaaattta ttaacttcaa ctttgtctga ttcattattt ggccccacac taaatgtgta
     3961 tttgcctgat ttttcatcaa ttttatcctg ttctgtcatt ttataacctt ctggtacaaa
     4021 cttttgtgcg aatgcttcat aagaaatatt aatatctttg taagtatcta caacttttag
     4081 attgtcagaa ctcttcccaa gtacatcatt tgctgtgtca agagatattt catcattgcc
     4141 atttttatat tcaaaactaa gtgcttttga ttttcctaaa acattatttt ctttgtcaaa
     4201 tgctttttta tttacagtat atgctccttt aaatttatat ccattactaa attcagaaac
     4261 tatattaggg gtaaagttaa agtctttttt tacttgttct gtagttggga tagatgtata
     4321 ggtagcctta gtacttgatt ttccaactaa actatatata tgtcctactg caagggctgt
     4381 tgtgctcaat atcaaagtaa tggctaaagt tgcaactaag ccttttctaa atggtaattt
     4441 gtgtgtttta ttattaatca ttttataatt ttcctctctt tctggtaaac tatttagtgt
     4501 tttgcttaaa ctattatgaa aactttctgg aacttctgga aacgaattat ttaatatatt
     4561 tttattcata tgattacctc cgtgttttct aatttagttt ttaataatct tcttcctctt
     4621 gataatctac tttttacagt tccttgaggt atatctaata tttccttaac ttcatctact
     4681 gaataacctt caatatagta aaggactatt ggaattttaa tttttttagg tagactttga
     4741 atagcagtat acaaatcgct atagtcatct ttttcatcaa tttttttgtt tttgaagaca
     4801 tcttcaaatg atagagattt taatcgtttg cgtcttaatg aattacattc atttatgact
     4861 attctaatca gccatgtttt aaagtattgt tcttccttaa gagaatccaa cttttcatat
     4921 gcttttaaaa tagcattgtt gatggcatct tcacagtctt ggtcgtttcc tagaatagac
     4981 ttagatactc gatacaaagt ctgttctgat tcaagtatat tgtttgtaaa tgtagtttta
     5041 tccaactaag ttccttccct tctatgcaaa tcgtagcgct acttttttgc ctttcactta
     5101 ttagataaaa ttttactata gatggttcac tttttttatg attatttgat aaatttaagt
     5161 ttgaaagttt tgcctattct atacaaatat tctataatat atttttttct agtattttcc
     5221 cctcatatat aaagccatgt agatatatta aactttagaa gccatttata tatttagttt
     5281 tatagtaagt gtttatattg agtaaattag aaaatagtaa gtatttaatg ttgagtagtt
     5341 agaataacaa tgcttttgga ttatttactt catgtacaga tttaaaataa gttttttaaa
     5401 taatgagtaa agataacagt atcttgacta aaagtaggct tttaagaaaa aacaatgaaa
     5461 cttaaatgag aattaagagt tagaaatgtc attattttag atagagatga acataaataa
     5521 acttaaaaaa tataaattat aaaaataata atttttttta aaataataaa gttttttgat
     5581 taaaagtttt atattgaaat gtcaaaataa taaaagacct tataagttaa ttacaggtta
     5641 aaaaaataat atgtgaattt tctgatattt actaattatg aataaaatat ttaagtatta
     5701 atgtttttag tgagacttta agacagataa tctcctatta aagatactat atcttagata
     5761 aaataaatta aaacaatata aaaacataac aagattacag aaagaaagct cacaataaaa
     5821 tgctgaaaaa tttattttaa ggaggaataa agtatgaagt ttcaagaaat gattaatagc
     5881 ccaggtcttt ggattgtttc tagtttttta gtaattattt cagttgttca agcaatcgta
     5941 tttatgaaag aggcactaaa agaggcttca aatcttggta ttgaaaggaa aggaattaaa
     6001 gcagcaattc gctcagctag tgttacagcc attggacctt ctctatctcc tgttattaca
     6061 ttattatcac tggtagctgt gattggcgct cctacgactt ggatgaggct ctgtgatgtc
     6121 ggagcagcta gaacagagct tggagtaata tctcttacat ccaatttatc tggggtagaa
     6181 gtaggtagtg ctgcatttgg agcagaagct ttttcgtatg cactatgggg gatggcttta
     6241 aataacttag gttggctatt tgttgtattt attttgggtc atagaatgcg tggaattgtt
     6301 gaaaagatga acatgaagta taatcctact tgggttaaaa aactacttgc aggagctaca
     6361 gttggattat ttgcttacct tctttcaaat caaataaaaa catttgaaat accaaaactt
     6421 acaccagcaa ttatttcagc tatagttatg ctagtattga caactttatt taaaaagaat
     6481 caacgattac aagaattatc cttaggtatt gccatgttaa ttggtatgtt tggtacacag
     6541 attatattat cgtgattaaa acggataaga ggtgataatt atgtatgata aaaagatgat
     6601 aaaaataggg agaatttcta taggtcttgc aattattgca aactttattc ccgctatcta
     6661 tgtaggtatt cgctttggtc agatgccaat gctttctgtt atatttcaaa tttgggggtt
     6721 agtcgctgcg acttatgggg ttagttggat tgttcaacct atagcttatt atcctacact
     6781 aggagctcca ggttcttata taggttggct tgcaggttct gttggagata tacgtatgcc
     6841 tgcagcatca atggcacaga aaattgcagg tgtagaagca ggaactcatg agggtgaagt
     6901 tgttggaaca attggtacat gttgttcaat ctttgtatca gcttctatga ttaccatttt
     6961 taccattgta ggctataaag taattccttt gttacctgaa tttgttacta attcatttaa
     7021 ttatatactt ccagcattat ttggagcaat ttatgttgat attgcacgta aggatattcg
     7081 agctggtgga tgtacgattg ctgtagcgtt agcaattatg tactttggtg aaaaaattgg
     7141 tataccaggt ggattattaa cattgtttat tgtgttaggt gggatactta tcacaagggt
     7201 cttctttgta attgataaca ataaaacaaa agaataggat tgcttattaa ggagaaagac
     7261 tagaattatt tgttgagaaa aaagaatagg attgtttatt aagaaatatg aatataaata
     7321 agtcttgaaa ggagaaaaag catgtttgat gttaaaattg tcaatggaat aatcgttgat
     7381 ggtacaggaa attcaagata taaaagtgat gtagggattg taggagacaa aatcatggct
     7441 attggagatt taagtcaaaa agaggctaaa gagactatag acgcaactgg aaaatttgta
     7501 tcacctggtt ttatagattt ccatactcat tctgatttat ctcttgtgta tgataaatac
     7561 acaagaagcc gtatccatac aggtgtaaca acagatgtta ttgcaaactg tggtatagga
     7621 gttgctccga taagagaaga gaagaagcaa gagttaattg attatcttgg aactaggata
     7681 attggtacaa ttccaacaaa attagagctt cattggaata caatgcaaga atactttgat
     7741 tacttaactg aaaattctcc agcagtcaat gttgtagctt atgtagcaca aggacctgta
     7801 cgtatcaatg aaatgggatt ttcaaaggaa ccagctactt tagagcaact taaaaatatg
     7861 aagttggaag ttagaaaagc tatggaagct ggatgtgtag ctctttcatc aggattagtt
     7921 tatttaccag gagcatacac aaagaaagaa gaaatggctg aattatgtaa ggaattgata
     7981 ccatacaatg gatactatat atctcatatt agagatgaag gtgatgaaga aatggaagct
     8041 cttgatgaag caatttatat agctaagact gcaggagttc ctctacatgt ttctcattta
     8101 aaagttatgg gtcataagaa ttttggaact attgatgagg tatttaaaaa gctagatgaa
     8161 gctgaggcag atggtttgga agtaactttt gattgttacc catatacagc tggaatgaca
     8221 tctttgggtg cacttttacc tccttgggct tttgaaggcg gtgtagaaaa tatggtaaaa
     8281 cgattagaag tacaagaaaa tagagacaga attataaaag agttggagga agggattcct
     8341 ggatggcaat gtttctacca attagcaggt gggtggaacg gtgttgtact agcctctgta
     8401 atgactgaag caaataaata tgtagagggt aaaactttaa tggaggtagc caaaatcaat
     8461 ggtgaaaatc catttgatac gttctttagg cttttgattg aagaaaaaag taaaattcaa
     8521 gtagttgttc atacacaagg tcaagaggat acagataagg ttgtttgcca tccaaagtca
     8581 tgtataggtt ctgatagtat ggacctttct acagaaggtt tactttctct tggaaagcct
     8641 catcctcgtg catttggtac ttttggacga attttctctt actatgttag agaaaaaggt
     8701 atgttgactt ttgaggaagc agttaaaaag ataacttatc tttcagcaaa acgcttaggc
     8761 atttataaag aaaggggtct acttaaagaa aattattttg ctgacattgt ggtatttgac
     8821 ccagatacaa tagaagataa agcgacttat agtaatccta aacagtatac agtgggagtg
     8881 gaatatgtgt tggtgaatgg taaaattgca ttggcaggag gaaagcaaac tgatgtatgt
     8941 gctggacgtg taattaaaaa tcctcttagc atagcaaaat agaatacatt aagaactttt
     9001 ataaaaatag tctttctttg aatattaagg aaggctattt ttgttaaatt aataaagatt
     9061 actctacttg tgttttctaa agaatttaac tttaagtaga aaaaacaata tattaattgt
     9121 aaaatgtaat taatattaat gaataagatt taaatacaaa aatttaaata caaaaatgtt
     9181 tcaacagata gtcgtaatta aaaaacttaa agtaactttt tatattaggt ataattgatt
     9241 attcaaaatt ctatgaatca ggagtcctgt gcctttagtc atggtaggtt tagaaaatgt
     9301 tttaagagat aatagtatca ttaggaaagg agagacgaaa tgaaaatact ttatgtagga
     9361 ccaggtatgg taatcgataa aatactagca gtaagtaaaa agaattttcc taatattgaa
     9421 gcagattttc ttagatatga tagatatatt gaagtacctg atttattgga aaaatataga
     9481 ggtagagtgg atgcagttct ttttacaggt aagtcgccat ttaaattttt tgaaaaaaga
     9541 caaaaagatt ttgtattgtc tgattatatt cctagacatg aaacaacatt gtacagagtg
     9601 ttgcttgaaa ttacatattt gcttaaattc gatattagta gacttagtat aggtacttat
     9661 gataaggcta tgatgaagag attgtataaa gaaattggag ttgaatttaa ggatgaacat
     9721 atgttttttg cagagcaaaa gtatttagaa gaggactata taaagtttgt gcttgaattt
     9781 cataaatata attatcaaaa taatgatgta tgttgttgta ttacaggtct tgaagaggcc
     9841 tatcatataa tgaaaaaaga taatattcca gtagttttag ccttgccttc tgaggacgta
     9901 atggtgcaaa gtataaaaaa cattcagatg cgttatattg caaagaaaaa caatgagaat
     9961 cagattattg ttcttgctat taaactgaac atgccttcag aatattcact aatgaaggaa
    10021 gatgagtacg cttatctttc acaaaggatt aagattcttg ataaactata ccatttcaat
    10081 agccgtatag atggtgtttt ggtagagcag agtagaagtg aatttatgat ttttacaact
    10141 aaaaaaatac ttgagttaga aacaaagaaa tacagagata tttatttgtt ggatatgatt
    10201 cgtgaagttt cagttataaa cacttatata ggaattggtt atggaaaaac agcaaatgaa
    10261 gctaaattta acgcttatga gagtattaag atggctcaaa gtcaaaaaaa tgatgcagca
    10321 tatgtagttt ttgaaaatgg agaaattatg ggaccactaa agccaaatcc tactgtcaaa
    10381 gagaaaaata gttttgatga acgtttttat caaattgcta cagagacagg gctaagtgct
    10441 aatactgtat ataaagtatt caataaaata ataaatagtg gaaaaactga atttacatca
    10501 aaggaattag ctactatatg tggtgtaagt attagaacta tggacaggat tatacttaga
    10561 ttgtgtgatt ctggttattg tgaggtagtg agtgaacagc ttatgagcaa gtatggtaga
    10621 cccagtagaa tattacgttt taaacctttt ctgttgtttt aaatagatat aagtcaaaaa
    10681 ttaaattttt atgataacat tttctttaca actttttaga tatatgttaa tatttagaaa
    10741 aatgcatatg tattcataaa ataaactcaa aacagctaaa aaatcattaa aaaggaaata
    10801 gtatgcataa aatgagaaag ttaatttata acttaaataa atctgggagg agataattat
    10861 gggaaaatat caggattcaa aaaaagttgt aagaaattat tttgaagcat tagaaaatgc
    10921 tactggggat gaggttgaaa atgtcttaaa gcaacatatg aaatcagatt ataactggaa
    10981 aggtgtgtat ccatttcgtg aacaagaagg cactgaaaat gtagcagatg tattttggaa
    11041 gcctttaaaa aaatcattga gtaatatgca aagacgacaa gatattttca ttgcaggaac
    11101 aaatgagatt gacaatagtg aatgggtaat gagtatgggg cattttatgg gactttttga
    11161 taaggattgg cttggcatta aacatactcg caaaatgatt agtttaagat atgcagaatt
    11221 taactgtgtt caagatggta aaattgctaa aactggatta tttgtagata taattgggtt
    11281 tatgattcaa gcaggagtta atccattgcc accacaaaca ggttcatatt ttgtatatcc
    11341 agggccaatt gaccataatg gattactttt tgaagatgca gatgaagttg aaggagtaaa
    11401 aactttagca ctagtaaata aaatggtaga tgatttatct gaattaaatg aaagtggtgc
    11461 tatgggatgc ccaccagaaa tacttgaaaa atcttgggct aaagatatga tttggtatgg
    11521 tccaggtgga attggtgctt cttatactat acctagatat caagagcaac accagctacc
    11581 atttagaaat aatttaaaag gaaagacttt taatgggcat gtatgtagat ttgcagaagg
    11641 taattttgct tgtttctttg gatggcctaa tctgactaat gtaccatgtg gaggtttttt
    11701 aggattacca ggtggagagg ttaaagcaga tatgcaagtt gttgatgttt attatcgtaa
    11761 gggcgataaa cttcaagaaa actgggtgtt aattgatatt ccttattggt tgaaacaaca
    11821 agggcttgat attcttgaga gaactaaaag tatttttaat gcttagttat gcatacgtat
    11881 tctaaaacaa agggggatat aaagtggcat ctaccaacaa aaataatgca acaagtaaag
    11941 aggaagaaaa agaagtttct acaagtgggc ttgaatcatg tacggttaaa gaaaacaaag
    12001 ctaaaatgaa tcaaactaat tttagtaata taaatgaaaa tcaaacaaat gagaataaaa
    12061 cgaacacata taaaggaaat atagataaag ggaatataga taaaacaaac acaaataaat
    12121 ccgacataaa taaagttaac atagatacag tggatacaga taaattaaat acaaatactc
    12181 ttactaaaaa aaataaaaaa gttatattta agggggaaga taatatgtca tctacaaaaa
    12241 tttactatgg agattcatta gaagtaacgc ctgttggagt aatggattac aatgattttt
    12301 caaaacagac aaaaagggaa caggaaatac ctggatttga ttctaagtat agagattttg
    12361 tagattatat tatgaagatt acacataata tctgggaaga aaaaggtata ggtgttattt
    12421 atgatacata tcacaataat gttacaatgc attgtggctc ttcaaattta gttggtatta
    12481 aagatgttat ttccaatact cttcaaacat tacatgcgtt tcctgataga agattaattg
    12541 gtcaaaatgt aatattgtct aactttggtg ctgatggttt tttatcttct caccgtgttt
    12601 tgtctacagc aactaactta ggtgatagta attttggacc agcaacaggt agaaaaataa
    12661 actttagaac tgtaattgat tgtgccacaa ctaacaatag aatccacgaa gaatggttgg
    12721 ttagagataa tttatggatt gttactcaat taggattaaa ccctcaggaa gtagcaaagg
    12781 gtatggcaaa ggcaagtgaa tctaaagtgc ttagtttaca atcaacttat ggtatctgtg
    12841 aatctatgga tggtcaattt atgccaacta agtatcaagc aaaagatgat tctgttggcg
    12901 aaatgatgct tgaaatgaca agccgcattt ataattataa gtatataaat gaagttaaaa
    12961 aatactatca tgataatgca gtagtacatt ttatatgtga taaagattta aatggctatg
    13021 atgagattca aggaatgatt gtaagtttac ttgcatcaat tccaaatgga agttatgaag
    13081 tggaaagagt aacttgtaat caaagagaaa aaaatgaagg ttatgatgta tctgtaagat
    13141 ggagattacg tggaataaat gaaggtatag gattttttgg acagccttct ggaaagcata
    13201 tagaagtaat gggaatcaat cattatcata tactacaagg taaagtaaag gaggagtgga
    13261 taacttttga tggtatggat gtattaaaac aaatgtatat gggagtagaa gaataaagct
    13321 gtttagagta taaatagttt tgaaatatat agggaagtat tgctttataa aatttaagtg
    13381 gggaatgtat atgaaaaata gatgtttaaa cttttagcaa aattatgact aaatttaaaa
    13441 gggggaatta taaaaatatg aaaacaacgg ttgaaataga aaatgatatc atattaggaa
    13501 aagactattc aaacctaaaa agaggaattg catttttttc aattgcttta atatactttt
    13561 tttattgcta caattttatg gtgggtactt ttattaaacc aacaatgatt tatgctttag
    13621 cagatggggg atttggtttt tcattaaaac aaacagaaga aatatttgca gttatgtctt
    13681 ttggtacaat tccaggtaca tttatttttg gggtgatttc tacaaaaatt gggaagaaga
    13741 ggactttaat tagcgttgct ttactgattg gattgacaac atttatacca atgttatctc
    13801 ctacaaatat tatgttatgg aaaatagcac gtttgtgtac aggagtagtg ttgggaggcg
    13861 tatttggaac agctatgcct ttagttgcag atatgtttcc aagtaaatat cgtggtaagt
    13921 tagctgctat attaactgct ttattttcat tagcaatgat ttttggtggg aaagtatatg
    13981 gcgttttagg tgatgcaaat tggcaaatat tgatgtatac tgcgattata ccacctatag
    14041 ttggagctat cttagcaatc ttctttgtgc cagatgattt ggagtataca aaggaattag
    14101 ttaaaaaggg aaaagaaact ggtgaaaaga ttagctatat aagtatgtat aagggaaaat
    14161 acttatggat tggattggga acgattcttt tatcaggtgc aaattttaca gcatattcag
    14221 cattttcaaa taatgcaact acatacctag tgacaggaat aggaatgtca gcagcagtgg
    14281 ctgggtctat atatagttta caaggaattg gtcaattagt aggatattta ttctggggtt
    14341 caattgcaga taaatttgga agaaaaatac cttttatagg tatggcatta gcagcagtgt
    14401 ttgtttttat atatacaaaa ttaggtggag ataatacaac aacattctat atgatatcag
    14461 tattactagg tgttgctgtt ggatattctg gagcatgggg agcatactac acagagttgt
    14521 tcccaagtaa atatcgttcg ttgtcatctg gtatgtcatt taatggagga aggattatat
    14581 ctacgtttgc aatacctgct atagctggta cagcttctgg tactttaggt atgatgacta
    14641 tcttttacat atcaatcgca gtctttgtag caggtgctat tgtatggtta ttcttaccag
    14701 agacgttaaa taataaaaaa taaaatacta ggaatttatt ttgttactta gaaaggggtg
    14761 gcttatgatt tcatcaattg atgtatgtat tataatagga tatttgctat taatgttagt
    14821 tattggttat tattcaggaa aagataataa aaatcaagaa gattatttct tggcaggtag
    14881 gtcaatgcca tggattccaa ttgctttatc agttgcagct actatgatta gtgcaaatgg
    14941 ctttataggt ggtcctggat gggcatatgt agatggaatg tatccagtaa tggttaatat
    15001 tacagtacct ttagcaatat tttttgcact gagcattacc accccagtta tctataaatt
    15061 aaaaataacc tctatatatg aatatatggg acttcgttta ggaaattatt caagaggatt
    15121 aactattatt caatttttta ttaattcatt gattcaagct agttctatgg tatatattcc
    15181 agtgcttatt attcaaatga ttactggctg gtcactttat gctttagtcc caatagttgt
    15241 acttgtatca attatatata ctctattagg tgggattaag gcagttatat ggactgatag
    15301 tattcaaatg atagtagtaa taagtgctgt atttatagta attattgtag ccttaaaagg
    15361 aatgaatcta agtttctttg atacattaca aattgcacaa cagagtggaa aattaaatac
    15421 atttgatttc agtagggata tttcagtgac aaatactttt tgggctactt taattggtgg
    15481 aactgtaatg tggataagat acttttgttt tgaccaatct caagtacaaa gagttttaac
    15541 atctaaatct ttaaaatgtg caaaaaattc ttttgtagtt agtgcatttg ttatgaattt
    15601 agtttactac tttatgctat tggtaggagt aattttattt gttttttatg ggggaaggac
    15661 atttgaaact tcaaatgaaa taatgattac ttttatttta aatgaacttc cagtaggagc
    15721 cattggaatt attattgcag gtgtgtttgc agcagcaatg tctagtatcg actctatatt
    15781 aaacagtatg acaactgttt ttacgaagga tatttatgag ttttatttca aaaaagataa
    15841 caaagaatca tcattaaaag ttacaatgat tataactgta gttataggag ttgttatgac
    15901 aggttttatt attatgggat ttggaggaag catcaaatca attcttgacc ttgttggtaa
    15961 ctatatctca tactttgctg gaccagctac aggtgcattt gtactagcaa tgtttacata
    16021 taaagctaat gataaaggag tatctattgg ttttattgta gggttagttt taggattttt
    16081 tatttctaat aaatataatg tgagttggtt gtggaatcca gcaataggtg ctacaataac
    16141 attgatattt ggatatattt ttagtgtcat tttaaagaaa aatcataatg cagatgatat
    16201 taaaaaatac actgcatttg gtatgagaaa tcaccttatt tctcaaggaa tggataaagt
    16261 agatggagta tctatagtgc cattttcttt aggtaaacaa gaactaattg tattagcttt
    16321 ttttattatc caatatatta tattattttt gatacaattt taagaagaaa tactagatat
    16381 ttaaggagaa atactaaatg aatcaaaaga aagttcatta taataaatcg gctacctcaa
    16441 aagatgttgc aagattggca ggagtatctc aatcatctgt ttcaagagca tttggtagtg
    16501 caaatggaaa gggcgtaaaa cctgaagtaa gagaaagaat ttttcgtgta gcaaacgaaa
    16561 taggatatgt tcctaatttg gtagcacggg gaatgattag tggaaaaact aatgttatag
    16621 gattgatagt tggtgatagt ctaggtccat tttacaatag aattatcaat ttatttgtag
    16681 aaaaaattca agagataggt aaacagtgtc tcgtttttaa agttcctaga caacaaagta
    16741 tagatagtat aatttcaaaa gtaattcagt ttcaagtaga agctgtgatt attacagctt
    16801 cggccatgaa taaggtgatg gctgagactt gtgaagaaaa caatattcct gtgattcttt
    16861 ttaatcgttt tatacctggt ataaaaataa gtacagtcta tgtagaccca attgaaggtg
    16921 ggggaatggc tgctgaatat ctgcttaaga aaggtcataa gaatatagga tatattcaat
    16981 ttacgagaga aacaagtgaa gaaatggaaa agaaaattgg attttattct aagttaagac
    17041 aaagtgggat tcataatctt aaagaagaat ctgcaaacta tgattatgat tctggatatg
    17101 aagcaggtaa gagaatgtta gcattatcaa atcctccaac agcaattttt tgcacaagtg
    17161 acttgatagc tattggtgta atggatgctg caaggtttga gtacaagttg agggtgccag
    17221 aggatttatc agtgatagga tatgatgata ttcaaatggc ttcatggaag agttataatt
    17281 taacgacgat tagacagcca ctagatttgt tgattgaaaa aacaattaac atacttaagt
    17341 ccttattaaa tgaagaaaat ccagagtcag tcgttgaaat gttaaaacct gaattgattg
    17401 aaagaggttc tacactttaa gtggtagata tttaattaag tgatagatat ttaattaagt
    17461 ggtagatatt taattaaatg gtagatattt aattaagtgg tagatattta attaagtggt
    17521 agatatttaa ttaagtagta gatacctaat taagttgtag atatctgata agaaattttt
    17581 aagttttcaa tcgttctaaa ttgtgagtat aaaaatctac taaatttagt tatgtaaaat
    17641 ataaattata ggtgtagaaa ctaggctact agcttttata ccacttcaaa cattactgga
    17701 ggtagttaag tttacagcag tttagtttta tgtagatata atattctgta aatagacaaa
    17761 attaaaatat gtaagtgtct caaaatgaaa tttttagttt atgaggcact tttttgtata
    17821 aaatcaaatg tatttttata actttaacaa taaaaagagg cttatctcta ttttgagaca
    17881 gcctcaaatt tttaaaacta tattagttta cagcttcttt tcctatcaaa tcttttaact
    17941 cttcatgagt catagtttct ttttcaaata agaatttaga aacagaatgt aaatcttcaa
    18001 gattatcctt taacatctct aaagtctctt tataacaaat ttcaactata cgatttgctt
    18061 ccttttgaac cttatcacat aagaaagtct tatcatttcc atcaatagtc ataaatccta
    18121 agttactcat accatattca caaaccattt ggttagctat ttcagtgact ttctttaagt
    18181 cgtcctttgc accagtagat ttatgattaa atattaattc ttctgaagcc tttccagcaa
    18241 gtaatatttt tatttttcca atcaactcat ccttagtata aatatatcta tcttcatcag
    18301 gtaattgaag aacataacct aatgcttgtc ctctaggaac tatagatatt ttttgtatag
    18361 gacaaattcc tactatatca cttacaagag catgtccagc ttcatgatat gctactattt
    18421 ttttctcttt ttcaaccaat gcagagtttt tagattctag ccctgcaata actctttcaa
    18481 gtgccttgtc aaaatgttct gatgtaatac actcactgtc atctctaact gcaaatatag
    18541 ctgcttcatt tgctatattt gaaagatgag ccccattgaa accatgagtt tttttagcta
    18601 aaagttctag atttacagat ttgtctatag gtttgtcatc tgtatgtacc tttagaattt
    18661 caaatctagt gtgatagttt ggtgcaccta tatgaatgtg tctgtcaaat cttcctggtc
    18721 taagtaaagc ttcatctaat aagtcaagtc tattggtagc acctattatt aatacattgg
    18781 aatctttatt aaatccatcc atttcaacta aaagttggtt tagtgtttgg tctttttcgt
    18841 tgttactttc aagatgtctc tttgctccta cagcatctat ttcgtctata aatattatac
    18901 ttggagcttc ttttctagct ttttcaaata gagttctaac tctttttgct cccacaccta
    18961 catatttttc aacgaactct gaaccagtaa cattaaaaaa tgatgagttt gtttcaccag
    19021 ctacagcaga tgcaagtagg gttttacctg ttcctggagg accataaaat aatactcctt
    19081 taggtatttt tgcacccatt ttttgatatt tttgtggtga cttcataaaa tcgactattt
    19141 caaatagttc ttcttttact tcgtctaatc cagcaacgtc tctaaatgta gtctttggtt
    19201 ttgtagaaag tgaatcatct gtttgattat ctctttccat ttttgtctgt gcaaagacag
    19261 gagctggatt gttgattttc ttaaaaaagt tgtttagcat tttcatattc acacctcagg
    19321 taattaatta ttgttaatca attttatatt ttccatattt actatttttt attatttatt
    19381 tttcatggaa aaaatataca tgttatctaa ataaaaataa atttgtaaga tgtatgaaaa
    19441 aatgaattta tgtatataga gatttctact tatgtattga ataaagtatt acaaattata
    19501 aattataaat tatgtattga ttatatattg agtaaagtat tataaagcat gtattgatta
    19561 agtatttatt aagtattgaa taaaatatta caaatttagt tgaaatgaaa atgataaaaa
    19621 atgttgtact atattttaca aatcatataa atagagaaat tgttgtagca caaagtagta
    19681 ggtagtatat tagaatataa ttataggatt tgtt
//
LOCUS       DAEOTL010000078        19574 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEOTL010000078 DAEOTL010000000
VERSION     DAEOTL010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.078"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            55..360
                     /locus_tag="KRH82_003037"
                     /pseudo
     CDS             55..360
                     /locus_tag="KRH82_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            373..1278
                     /gene="truB"
                     /locus_tag="KRH82_003038"
     CDS             373..1278
                     /gene="truB"
                     /locus_tag="KRH82_003038"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBG8656303.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYCNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            1409..2338
                     /locus_tag="KRH82_003039"
     CDS             1409..2338
                     /locus_tag="KRH82_003039"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBG8656304.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            2442..2699
                     /gene="rpsO"
                     /locus_tag="KRH82_003040"
     CDS             2442..2699
                     /gene="rpsO"
                     /locus_tag="KRH82_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBG8656305.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            2939..3784
                     /locus_tag="KRH82_003041"
     CDS             2939..3784
                     /locus_tag="KRH82_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBG8656306.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            3909..6020
                     /gene="pnp"
                     /locus_tag="KRH82_003042"
     CDS             3909..6020
                     /gene="pnp"
                     /locus_tag="KRH82_003042"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBG8656307.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            6286..7029
                     /locus_tag="KRH82_003043"
     CDS             6286..7029
                     /locus_tag="KRH82_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBG8656308.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            7187..8434
                     /locus_tag="KRH82_003044"
     CDS             7187..8434
                     /locus_tag="KRH82_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBG8656309.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            8469..8714
                     /locus_tag="KRH82_003045"
     CDS             8469..8714
                     /locus_tag="KRH82_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBG8656310.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            8724..9947
                     /gene="dapG"
                     /locus_tag="KRH82_003046"
     CDS             8724..9947
                     /gene="dapG"
                     /locus_tag="KRH82_003046"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBG8656311.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            10060..10794
                     /locus_tag="KRH82_003047"
     CDS             10060..10794
                     /locus_tag="KRH82_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBG8656312.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            10917..13328
                     /locus_tag="KRH82_003048"
     CDS             10917..13328
                     /locus_tag="KRH82_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBG8656313.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDDEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            13331..14389
                     /gene="mnmH"
                     /locus_tag="KRH82_003049"
     CDS             13331..14389
                     /gene="mnmH"
                     /locus_tag="KRH82_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBG8656314.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            14383..15717
                     /gene="rimO"
                     /locus_tag="KRH82_003050"
     CDS             14383..15717
                     /gene="rimO"
                     /locus_tag="KRH82_003050"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBG8656315.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            15704..16246
                     /gene="pgsA"
                     /locus_tag="KRH82_003051"
     CDS             15704..16246
                     /gene="pgsA"
                     /locus_tag="KRH82_003051"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBG8656316.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            16534..17580
                     /gene="recA"
                     /locus_tag="KRH82_003052"
     CDS             16534..17580
                     /gene="recA"
                     /locus_tag="KRH82_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBG8656317.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            17756..19297
                     /gene="rny"
                     /locus_tag="KRH82_003053"
     CDS             17756..19297
                     /gene="rny"
                     /locus_tag="KRH82_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBG8656318.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
BASE COUNT         8002 a         1986 c         3790 g         5796 t
ORIGIN      
        1 tatgcaaaat tctgtgaagc aggaaccctg tgactttagt catgggaggt tcagtcaaag
       61 gtatctagta tagttttaac tcaagacatg atgaatagaa ataatattag ctttaatgat
      121 gttgatggaa taacaacata tacaagagac ataaaaggta tagaagttgg aattttattt
      181 aaagagaaaa aacaaaatga aattaaagtg agttttaggt caaaaaatta tgttgatgta
      241 agtgaaatag ccaagttatt tggcggtggt ggtcatgtaa gggctgctgg atgtactatt
      301 agagatagta ttgataatgc aaagaaaatg gtactagagg cagtgttaaa atcaatttaa
      361 ggtgacagta aaatgaataa gattataagt atattgaaac ccacaggtat gacatctcat
      421 gatgttgtaa gtagagtgag aaagatttta aatataaaaa aagttggtca tacaggtact
      481 cttgacccag atgcttcagg tgttttacca atctgtatag ggaaagctac aaaagtatgt
      541 gaagttattt taaacaaaga taaatcgtat atatgtgagc ttactttagg tataagtaca
      601 gatacttatg atgcttcagg tgaaatttta aaaaaagttg atgattttaa atttagtaat
      661 gaagacatag aaagagcttt tgacacacaa agaggagaga taaatcaact tcctccaatt
      721 tattcagctt taaaggtaaa tggaaagaga atgtgtgatt tagtaagaag tggtagacaa
      781 tctgaaatta ctttaaaaac aagaagagta aatataaaag acataaaaat actaagtata
      841 aaaggtaata aagtaatgtt ttatgttgag tgttctaaag gtacttatgt gagaagtatt
      901 tgccatgata taggagaata tctaggttgt ggagctcata tgtcgttttt gaatagaaca
      961 tcttctggta aatttgactt agataattca ataacattag aagaattaga attattttat
     1021 gaaaataaaa ctttagacaa atacttatat gatatagatt atgtccttga ttcgtttaat
     1081 tatgttgtat taaaccctaa tgctataaaa tattattgta atggtggctc aatagatgat
     1141 aaaaggtttt taaaaaataa tttcgataaa gatgatgaat ttgtaagagt atacagtaca
     1201 gataatttct taggattagg aaagttatca aaacacaata atacaataag tgttaaaagt
     1261 gataagatgt tcatataacc aatgtattta aaaaaacaac aaaagagata gtactataat
     1321 aacttctata gtctatctct tttacttatg ctataatagt ttgtgaataa gttaagagta
     1381 aattatattt tagcggggaa catttattat ggtgattata aaatctataa aagaaatagc
     1441 aaacataaaa gaaagtgtca ttaccatagg aaattttgat ggtgtacaca aaggacatca
     1501 agttcttata ggaaaaacag ttgaacatgc aaaaaaagaa aatatacaga gtattgtatt
     1561 tacatttgca aatcatcctg taaattactt tagaccaaac tcaacaaaaa atattataag
     1621 caatgatgat aaaataaaat tattagaaga tttgggaata gatatagttg taatcatacc
     1681 atttgatgag tatatgacta aaatacctgc aaaggatttc gtagatgaga tactagtaaa
     1741 aaaattaaaa gctaaaaaga tagtaattgg acatgacttt acatttgcaa gggcaaaaga
     1801 aggcaatgtt aatctattaa aaagcttaga acatgaattt ggttttgagg tagaagtaat
     1861 aaaacccatc aaaatcaatg atgtaagagt gagtagtact tatattagaa gtttagtatc
     1921 ccagggtgat atggctaatg tcaaggaata tttgggtaga aattacaagt tagaaggttg
     1981 tgttatacat tctaaacacc ttggaagaac tataggattc ccaacggcaa atattgacct
     2041 taagaataat atgctcgttc caaagagagg tatttatgct tctattgtac atattggaga
     2101 tgagacttat tttggtgcta caaatgtagg ctataaccca acagttaatg gaaaaacttt
     2161 gtctattgaa acaaatattt tagagtttga tagagatatt tatggggaaa atataattgt
     2221 tgaatttttg gaaagaataa gagatgaaag aaagtttaat tcaatagatg acttaaaaaa
     2281 tcaattgtat aatgatacaa attatgtgta tgaaaactat gtttgcaaaa acaagtaatg
     2341 tatgataaaa tgattaagga aaataaccat tactcggcat ttgaatactc caatcaatgc
     2401 ttagtaatag gcgtttctaa aaaaatacgg aggtaatcta aatgataaac aaatcagaaa
     2461 taataaaaga atatggaaga gctgaagggg atactggttc tccagaagta caaatagctt
     2521 tattaacagc tagaataaac gagttaaatg gacatttaaa aactcataag aaagaccacc
     2581 attcaagaag aggactatta aaaatggttg gtagaagaag aaacttatta gcttacttaa
     2641 aggaaaaaga tcttgaagga tatagagcat taatagctaa attaggatta agaaagtaat
     2701 ttcattcttt ataaaaaagc aggtatagtg tatacctgct tttttatagt taattcatta
     2761 taaagtaaaa tagttaataa taaaagtagt ttatatgtta taaaaaatta taaaatgaat
     2821 aatattgggt aagaatatta aaatagtata caaatacata atcaatttaa aaggaaagac
     2881 aggataaata tagaaatttt ataacaggat aattagttgg aataaggagg atattatttt
     2941 gaaaataaag ttagtatgcg atagtttgtg cgatattcca gatgaaatat cagaaaaaga
     3001 ttatatagag atagttccac ttacagttat ttttaatgat agggaatata tagaaggagt
     3061 agatataaag aaagaagagt tttataaaaa agtaaaagaa atcaagcaaa tacctaaaac
     3121 ttcacaagct acatatatgg agtttaaaga agtgtttgat aagttcataa cagaaggtta
     3181 tcatataatc tgtatgacag gggctgcaaa cgcatcagga acttttcaaa gtgctatgat
     3241 agctaaaaat gatgtaaatg aaaatgaaaa aatacatata tttgatacta gaaatttatc
     3301 tctaggtagt ggacaatatg ttataaaggc atgtgaactt cttgaagaag gactgggatt
     3361 tgaagaaatt atagatgaat tagaaaatac tcgcagtagt gtaagattgc tttttgcacc
     3421 atatacactt gattttttaa agcagagtgg aagagttcca gttgcaactg ctttgatagg
     3481 aaatatgtta aatataaagc ctatattttt ctttgataat ggggaagcta agttggtaaa
     3541 taaggttaga ggaataaaga atatagcaag taaattggtc gatataattt tagaaatgaa
     3601 tgaagggtct ttagaaggaa aaatcgtcac aataggttgt ggagataatt tacacgattg
     3661 tgaaatatta aaagatgaag taaataaaag aataaaagca agaagagtat tatttactcg
     3721 aggaggagtt tctatttgct ctcatacagg gccagatata ttggctataa gttgttctaa
     3781 ttagtagtaa tataaggttt ttgcatatat atgtgaatat aattttatat tgttaattta
     3841 tagtattttt gataatatag taaatagagt gatatacgtg ttttttaata agaggaggac
     3901 aagcattaat gtttgaacat aaaatattta aaatggattt tgcaggaaga gaactttctg
     3961 tagaaatagg aaagatttgt gaaatggcta gtggtagttg tatagttcga tacagtgata
     4021 gtatggtaat ggtaaataca actaaatcag ccaaacctag agacggaata gacttttttc
     4081 ctttaagtgt ggattatgaa gaaaaattat actctgtagg taagatacct ggaggttttt
     4141 taaagagaga aggcaagcct tcagagaaag ctatacttac atcaagattg atagatagac
     4201 caataagacc tttattccca aaaggattta gaaatgatgt tcaggtagtt gcaacagttc
     4261 tatcagtaga ccaagattgt acaccagata tagtagcaat gataggttct tcaatagccc
     4321 tttctatatc agatatacca tttaatggac caacaggttc agtatgtgtt ggccttgtag
     4381 atggtgcatt tgttgtaaat ccaaacgcag agcaaagaga aaaaagttca atgcatctag
     4441 ttgtttcagg tacaaaggaa gcaataatga tggttgaagc cggagctgat gaagttccag
     4501 acgaggtaat gcttgatgct attttatttg ctcaccaaga aataaaaaaa atagttgagt
     4561 ttatagaagg tatagttgca gaagttggaa aagaaaaaat gcctgttgaa ttataccatg
     4621 caggagaaga aataactcaa ttggttcgcg aatttgcaac tgataagatg aaaaaagcag
     4681 ttcagacttt tgaaaagtta gagagaatgg aaaatatgga tagagttaaa gaagaaactt
     4741 tagctcactt tgaagaaact ttagaagatt ttgaagattt tgttggagat atagaagaag
     4801 tattacaaga tataataaaa gaagaagtaa gaaaacttat agtacatgaa aatgtaagac
     4861 cagataatag aaaacttgaa gaaataagac ctatatggtg tgaaactggc atgataccta
     4921 gagctcatgg ttcagccata tttactagag gacaaactca agtacttaat gttgctactt
     4981 taggtgcttt aggagatgtt caaaaactag atgggttaga tgaagaagaa aacaagagat
     5041 atatgcatca ttataatttc cctgcatata gtgttggaga agctagacca tcaagaggac
     5101 caggaagaag agaaatagga catggtgctt tagcagaaag agctttatta ccagtaatac
     5161 catctcaaga agaatttcct tatgctatca gattagtttc tgaagtatta agttcaaatg
     5221 gttctacatc tcaagcaagt gtatgtggct caacattatc tttacttgat gcaggtgtac
     5281 ctataaaaga tatggttgca ggtatagcaa tgggacttat aaagcatgat ggtaaggttg
     5341 cagtgctttc agatatacaa ggtatggaag accatttagg cgatatggac tttaaagtag
     5401 ctggaacaga gtatggtata acagcaatac aaatggatat aaaaattgat ggtatagata
     5461 aagaaattct acaacgtgct ttaaaacaag ctaaagaggg tagaatccat atactaggag
     5521 agatgagaaa aactatatct cagccaaaac cagaactttc accatatgca cctaagattg
     5581 ttaaaatgca aataaatcct gacaagataa aagatgtaat aggacctggt ggaaagataa
     5641 taactaagat aatagacgaa actggagtta agatagatat tgaacaaact ggggaagtat
     5701 ttatatcagg tattgagatt gatatgatta agaaagctca agaacttata aataatatag
     5761 tagttgaacc agaagtagga aaaacttata aaggtaaggt aagtagaata atgaactttg
     5821 gagcatttgt tgagatactt ccaggaaaag aaggattact tcatatatct catatagctc
     5881 atgaaagagt tgccaaagtt gaagatgtat tgaatatagg ggatgaagtt gaagttaaag
     5941 ttacagagat tgatgaaaaa ggaagagtta atttatcaag aaaagttctt ttaccaaaac
     6001 cagaacataa aaataaataa cttattatat aattaaaagc aaagtcttag gattttgctt
     6061 ttttaaatac aaaaaagtag ataattttaa aatgatagtt atggatggct tatagttctt
     6121 tttctgtcag gctttactct tataaagaag ctatttaaaa gctgattaat agagagcttt
     6181 attgatatat atagaatcac ttaagttata tttagtgcat aaacagagct tatttttaat
     6241 agtattaaat aagaaacaat ttgtacataa ttagggggag ttttaatgat aatgatggta
     6301 cttaataaga gtaagctcaa aaaaatcata atactaattt tagtagtgtt attagtatta
     6361 tcaggagggg taatggtatt aaagttattt aacaacaagc cagtatttaa tttatttaat
     6421 ggtgtagatt taccatatga aagaggtaca aaggataaaa gtggatatgt tgcattaacc
     6481 tgtaatatag accttggatg ggaaacagag tacgtagaat ccattttaga aacacttaaa
     6541 aaagaaaatg taaagattac atttaatgta actggaaaat gggcagaaaa gaataaggat
     6601 gaattattaa agataaaaaa acaaggacat gaaataggta atcatggata caaacattta
     6661 gattattcta cattatcata tgaagacaat tatgagcaaa tagagacctc taaaaagata
     6721 attgaagaaa ttataggtga aaaaactaaa ttttttcaag caccagcagg ttcttttggt
     6781 ccagaaacag taaaggctgc taaagcatta gggtatactt ctatcaaatg ggatgccgat
     6841 actatagatt ggaaatacaa agaccaacca gaggtaatca ttgatagaat gaagaaaaaa
     6901 gacattaaag atagtagtat aattttaatg catccaacca acgcaacgac aaaatgtata
     6961 gatgatatta tagctattgt aagagaaaaa ggactaaaac caggaaaact tagtgatgta
     7021 tttaagtaga caaagtataa atatttggtt aagattgtat aagttgtagt tgaattaatt
     7081 aaaagactga cttataatgt aatacatata aaaaataaat ataattaaaa catagtgttt
     7141 tcaataatcc aatatgaaac aaagaataaa ttgttaggag aatgtaatgt ataagacaaa
     7201 aatactggaa aatgggctta caataattgg tgaagaaata ccatatctaa agtcaataac
     7261 attaggtatt tggataaatg caggctctag gatagaagaa gcacaggtga gtggaacttc
     7321 tcattttata gagcatatga tgtttaaagg aaccaaaaac agaacatcaa aagagattgc
     7381 tagttcaata gataatttgg gtggtcaaat aaatgcattt acaagtaaag aatgtacatg
     7441 ttattatgta aaactaatag atgagcatat agatacagga attgatgtat tgagtgatat
     7501 gatactaaat tctaaatttg ataaaaatga tatagataag gaaagactta taatattgga
     7561 agaacttaag atgtatgaag actctccaga tgacttatct tatgatttat tagtggaaaa
     7621 tatatatgct aatgatggat taggaatgaa tataattggg acaaaagaat ctctatacaa
     7681 tataactaga gaatccatgt tagaatactt aaataagtat tatattccaa ataacgctgt
     7741 tatttctata gctggaaatt ttaactttga tgatatggtg gagaaaatca aatcaaaatt
     7801 tggacactgg gaaaagaaaa atttaagtat agacataagt gaggctaagt ttaatccttg
     7861 ctttatatca aaaaataaag acactgaaca ggtgaactta gctatgtgcc taaaaggtat
     7921 tccttttgaa aatgatgaag aagtctattc aatggcagtg gtaaataata ttttcggtgg
     7981 aagtataagc tcaaggcttt ttcagaaaat aagggaagaa aaaggtttag tatattcaat
     8041 atactcatca cagacattat ataggaaatg tggtgaatta ggtatatttg caagcatgag
     8101 tacagaaaat ttacaagatg tatataattt aataaagaaa gaaattgaaa atataagaga
     8161 aaactatctt acagaaaaag aaatatctga aagcaaggaa cagttaaaag gaaattatat
     8221 attggattta gaaagtacta gcagtagaat gatgtctact ggtaaatcta tgttacttag
     8281 taaaaaagta aaaactacag atgaaatact tgaatgtata aataatgtta atattaattc
     8341 aataaagaag gttgttgata aggtattcaa tatcgaaaat attggtacat gtatagttgg
     8401 aagagatgta gaaaagattc tacacttgga ttaatattga aaaaagtaaa tctctggagg
     8461 tataaaatat gaatttatct gaaatagcag gtaaggaaat agttaacttg gtcacaggag
     8521 aaagattggg ggtcattgga gaatgtgacc ttatactaga tgaaactaca ggcggtatat
     8581 tagcgcttct aattccaaaa gaaaaaggat tttttgccag aagaaaagat aagtcatttt
     8641 tagaagtacc atggagaaat gtaaaaaaaa taggtaatga catgataatt atagaatatg
     8701 agggatatat ttaggaggaa aaaatgagta ttttagtgca aaagtttggt gggacatcag
     8761 tagaatcata tgaaaaaatg aatgaagtat gtaagatagt aaaagcatac aaaaaaaatg
     8821 atgaagaatt acaattagta ttagtagttt cagcaatggg aagaaaagga gctccatatg
     8881 ctacagatac acttataaat ttgtgtagtg cagtaaatga tgagccaagt aaaagagaac
     8941 ttgatttaat aatgtcttgt ggagaaataa tatcaggaac aattcttgct aatttattga
     9001 atgcacaggg gatagattct gttttcttta ctggtcagca agcaggtata attacaagtg
     9061 atgaatattc taatgcaaag ataaagtata taaatcctaa aaaggtaaaa agagctttag
     9121 atgatggtaa ggttgtagtt atagctgggt tccagggtgt aacagatgat ggagaaataa
     9181 ctactcttgg aagaggcgga agcgatacat cagcagttgc tattggtaaa gctttagaat
     9241 gtgaaacagt tgaaatttac actgatgtgg atggtataat gactgcagac cctagagtag
     9301 aaccaaacgc taaagtattg agttttatag actatgagga agtattccaa atggctgaca
     9361 aaggtgcaaa agtaatacat ccaagagcag tacagttggc taaaagtgga aatataactt
     9421 tagccataaa gaatacaatg aatccaactt ttgaaggtac aaaaataggt tctttatgta
     9481 gacacttaga agacaatata gaatatgaac aagaaagaga ttttaaggtt gctgttgcaa
     9541 ataaagatag cgtagcacaa gttaagatta agtcagcaga agaagtgttt acagaagtat
     9601 taaatgagat agaaaagaaa cttataacta tagatatgat aaatttcttt atatcagaaa
     9661 aagcatttgt tgtagaagat gctgatataa aatcattaaa ggaaatacta gataaatttg
     9721 aattagatta tgaagtaaat agagactgtg ctaaggtaac attgatatgt tcaagaattg
     9781 ctgatgaaat gtctggtatc atgtcaaagg tagttagagg attatcaaaa gcaggggtat
     9841 ctcttttaca aacatcagac tcaaatatga ctatatcttg tttagttagt gaagaagata
     9901 tgcatacagc agtacatgct atacatcaac aattttattt aaaataaact gtataataca
     9961 attatttttt aatcaaattt aagaatttca tatatatctt aatatatttg atttatttgg
    10021 taaaactaaa ttaaatataa ttttgatagg agttttttta tgaaagatta tagagaagat
    10081 aatgaaagat ttgataaaga taattgtagt gaagaatcta gttgcgaaga gagagaatgt
    10141 ataaagcaat ttggtaccaa tgaaatgcca cctcaacctc ctaaagatat tcaatgtata
    10201 actataattg gagaaattga gggacatttt ataggaaatc ctcaaaaaaa agctacaaag
    10261 tacgagcata taattccaat gctatactca attgaggaaa gcaatgatgt taaaggagtg
    10321 ttagttgttt taaacactgt tggaggagat attgaagcag gtttagctat tgcagaactt
    10381 ttaaacagta catctaaaaa agtagttact cttgttctag gaggaagtca tagtataggt
    10441 gttcctcttg ctacagcagg agattactca tttatagcac caacagcaac catgattata
    10501 catccagtgc gaactactgg tcttgtgatt ggtataaatg agacttttga gtattttaaa
    10561 aagatgcaag atagaataat tcaatttata ataagaacat caaatatcaa aaaagatgta
    10621 cttgaaaaac ttatgcatga aaaagatgaa cttgtaagtg atgttggtag tgtattaata
    10681 ggaaaagaag ctgtggatta tggtcttata gatgaagttg gaggactaaa agaagcactt
    10741 aaaaaattaa gagagcttat aaaagaatct gaggaagaaa aaaataatga ttaaaatttg
    10801 tttaaataat aaaatttatg atataatgat gtaataaagt aggagtgtta gtgttaaggc
    10861 attagcactt tttgctgtga aggggtaaaa cttgctaaaa ataaggagtg atattaatgg
    10921 ccacgaaaaa gaagaaaaaa aagaaggtaa ataccttaag ttttaatgca gaatatcata
    10981 atttaataac aatatttata ggtgtatttt tattatatag tttaaattct aattctatgg
    11041 gatggatacc tgtgttaatg caaaatcttt ttaagggact atttggaggg ctttcaatag
    11101 caataccatt tatagtaatt ataacaggac ttttaggatt ttttgatgga aatgaatata
    11161 tatataggct aagaaagact aaactatact acataattat tttatttata tttgtatttt
    11221 atggattatt aaatgcagga actcttcctg tagatagccc actaaaaggt aacatgtttg
    11281 atgatgttat gaaattgggt gtaagtggac aaggtagtgg tttgatagca acaactattg
    11341 cgtattatat gagtaaaata tttggtatag caggtggatg gttaataagt atcttcgcac
    11401 ttatactttc tgtaatgttt atatttaata tttctataaa agatttggtg tcaaatgcaa
    11461 aatcaaaatc taaagcatct aaagacagca atttaacgtt taaagataaa attgcaaata
    11521 tgaaaaaatc tgcaatagat atgatgactg atgaagtaga tgatactact ataaataaaa
    11581 aaccaggttt ctttaaaggg ttaatgtcaa aaggtcttaa taatgatgat gatgaagatg
    11641 aatattttga agaagaaaat agtgatggtg tagatgataa aactataaaa atagttggat
    11701 ttaataaggc agaagatgag tatttagaaa tattagaagg aactcaaagt atgccagagt
    11761 tagatgtttt aaaagaatta caaaaagcta ccaatgaaaa tccagttgta gatactaaac
    11821 cagaaaaaaa agttgatata gctaaaccta atttaaatat agaaaaaact caacctatga
    11881 gtattgtagc agagccagtt aatgaggatt attcaaacta taaaaagcct agcattgagc
    11941 ttttaaataa agtaaataag aagtctgatg aaaatggtaa aaagaaagtg ttgaaaaatg
    12001 cttctctttt agaaaagaca ctatcagatt ttggagtgga agcaaaaatt aatcaagtta
    12061 cagtcggacc tactataaca agatatgaaa tacaaccaag tccaggagtc aaggtaagta
    12121 aaattgtaaa tttaactgat gatatagctt taagtttagc agctaaaagt ataagaattg
    12181 aagccccaat tcctggtaaa agtgcaattg gaatagaagt tccaaatgaa gaagctcaaa
    12241 tggttggtgt gagagaagtt ctagaaagtg aagaatttaa taattttaac tctcctcttg
    12301 caatgggact tggaaaagac gtagcaggaa aaattataat tggagatata ggtaagatgc
    12361 cacacttact aatagctggt tctacaggtt caggaaagag tgtttgtgta aatacattaa
    12421 taagtagtat tttatataag gcaaatcctg atgaagtaaa attactatta atagacccaa
    12481 aagtagttga acttgcaaat tataatggaa taccacatct attgatacca gtagttactg
    12541 accctaaaaa agctgcaaat gctttaaatt gggcagttac agagatgaat agaaggtaca
    12601 aattatttgc agatgctcaa gtaaaagatg taacaagtta taatgagaaa gcggaagaaa
    12661 aacttcctaa aatagtaata ataatagatg agttagcaga tttaatgatg gcaagtgcaa
    12721 atgatgtaga agattatatt tgtagattag ctcaaatggc aagagctgct ggaatgcact
    12781 tgattgtagc aactcaaaga ccatctgttg acgttataac aggggtaata aaggctaata
    12841 taccatctag aatagcattt gcagtatcat ctcaaactga ttcaagaaca atccttgata
    12901 tgggtggtgc agagaagctt ctaggtaaag gtgatatgtt attctatcca cttggtgcag
    12961 caaaaccagt tagacttcaa ggggcattca tatcagagag tgagtcggaa aaagtaatcg
    13021 attttgtaaa aagtcaggtt aaagatggaa taaaatatga agaagatata attgaaacta
    13081 tatctaaggt taatacttca aagggtagtg atgaggatga gtttttgagt gaagcgatag
    13141 aatttgtcgt ggaaagtggt caagcatctg cctctatgct acagagaaga tttaaaatag
    13201 gattcaatag agcagctaga cttatagatt ctatggaaga aagaggaata attggagcaa
    13261 gtgagggaag taaaccgaga aaggtattaa taagcaaaca ggatttgcag aatttagaag
    13321 gtgaatagaa ttgtcagtta taaaaataga aaaagcactt aagctagata aagtaatatt
    13381 tgtagatgtg agaactgaag gagaatatga agaagaccat atattgaatg caatcaatat
    13441 gcctcttttt aaaaataatg aacataatga agttggaaca atttataaga tgcagggaaa
    13501 acatgaagca atacaaaaag ggtttgacta tgtatcgtat aaattaaagg atatatattt
    13561 acaagcagca gaacttgcat taaattatga taatattgtc atatattgtg caagaggcgg
    13621 aatgagaagt ggcagtatag taaatttatt atcatcatta ggtgtaaatg tatatcaact
    13681 tgaaggtgga tataaggctt atagaaattt tgttttagag tatttaaggc atgtaatgga
    13741 tacaaaaaac tttgtatctg ttcatggatt gactggtaca ggaaagactg atttgttaca
    13801 tttattagat gaaaaaggaa tagacgtact ggatttagaa ggcatagcta aaaacagtgg
    13861 ttctaccttt ggttttataa cttttgataa aaagccacca tctcaaaaga actttgaaac
    13921 aaaactattt gaaagtatat ttttttcgaa agagaattat atatttgtcg agagtgaaag
    13981 caaacgagtt ggaagtgtta cagttccaaa tgaaattttc gaggcaatga cacgagaagg
    14041 acatcatata ttattagaat gtgatattga aaatagagtt gatagacttt gtagagatta
    14101 tatttatgat aaagatgaag gtaatatatt gattttaaaa gaatgtataa acaagtttag
    14161 aaaaagattg ggtaataaag tagtagatga ttatattgat ttattagaat caggtgaata
    14221 taaagaactt gtaaaaagat atcttttaga atactacgac ccactttata tgcattcagt
    14281 agagaaatat aagtatagta agattataaa ttttaatgat acacaaaaag ctttagaaga
    14341 tgttatagac ttatatgaga gtatattgga aggagaaagt gaatgttaaa aatagcattg
    14401 gaatcattag gatgctcaaa aaatttagta gatgcagaaa taatgatggg aattttaaat
    14461 aacaaaggct ataaattaat tggagatttt gaagaagctg atgtaattat agtaaataca
    14521 tgtgggttta tagagtcagc taaacaagaa tctatagata cgataataaa ctttgcagag
    14581 ttaaaaaaaa ctggcaattt aaagttgttg atagtaacag ggtgtctagc ccaaagatat
    14641 tctgaagaat taaaaactga aattcctgaa atagatgcta tagtaggaac aggaagctat
    14701 caaaatatag ataaaatact taaagaatta agtgaaatgc atcaaattgt aagccttaat
    14761 gatatagagt ttgtatttaa tgaagattta ccaagatata tatctacacc tagctatatg
    14821 gcctatttaa aaattggaga aggatgctcc aataattgta cttattgtat aataccaaaa
    14881 ctaagaggta aatatagaag tagaaaattt gaagatataa ttaaagaagc taagaaatta
    14941 gctgaatctg gagtaaaaga acttgtggtt atagcacagg atacgacaaa gtatggtttt
    15001 gatttatatg gaaaagaaag attatcagaa cttttagaag aacttgcaaa aatagatgga
    15061 tttaagtgga taagggttat gtattcatat ccagaatcta taacagaaga attgatacaa
    15121 gttataaaga aatatgataa tatatgtagt tactttgata tgccaataca gcatgcaagt
    15181 aacaatattt taaaattaat gaatagaaaa actactaaag aagatatatt aaataaaatc
    15241 aatctgataa gaagtaatat accagatgct atacttagaa ctacaataat agtagggttt
    15301 cctggtgaaa cagaagatga cttcaaacaa cttgtggact ttgttgaaga ggttaaattt
    15361 gatagacttg gtgcatttgc atattcaaga gaagaagata caccagcaga tagattacca
    15421 aaccatatag atgaagaagt aaaaatacaa agaagagata ctttaatgat gattcaacaa
    15481 aaaatatctg aagaacttaa tgacaaaaag ataggaaaaa cttatgaggt gttaatagaa
    15541 gaacagatag aagataatgt atatacagga agaacacaag gtgatgcaga agaaattgac
    15601 agtatagtgt atgtaaaaag tgtagacaat cttgaagtag gagaatttgt aagtgttcaa
    15661 ataaatgatg caatggaata cgatttaatg ggagatgttt tatatgaact tgcctaacaa
    15721 gttaactttg tttagaatat ttttaatacc agtatttgtt ttaattatgt tgctcaatgt
    15781 accaaataaa tttttaatag cttgtattat ttttataata gcttcaatta ctgatgcttt
    15841 agatggaaaa atagctagaa aatacaatct agtcactgac tttggaaaat ttatggaccc
    15901 attagcagat aagttattgg ttatttcagc acttacatgt atgatagaag accatcttgt
    15961 aagtagttgg atggtaatta taatagtggc tagagagctt acagttagca tattaagagc
    16021 tatagctgct gctgatggaa aagtaattgc tgctggaaac agtggaaaac ttaaaacgat
    16081 aactcaaatg gtatctatag tgtttttatt gttaggtgct cagtttgaaa atgtattgat
    16141 attaaatatt ggtgaaattc tcattcttat agctacacta cttacattat attctggatg
    16201 ggaatatcta tataaaaata aagagctttt tatgtcttct aagtaaaaaa ttatgcttta
    16261 ataaataaaa actaatgatt aataaataaa aaataacaac ttaaaatttt aaaaatgtaa
    16321 aaaagggtat actattatag tatacctctt ttcattttaa gaatattttc ttttgtgtat
    16381 ataattatta ataatggttt ataaataaaa tgtaatgaat aaaaatataa tcattagtag
    16441 cgtttttaaa ttgactaggt ttgatttatg ttatataatt aatatataac aagagaacaa
    16501 atgtttgtag ataaatgaag ggatggtata gagatgagtg tagatcaaga aaaattaaaa
    16561 gcgttgaatg aagctttagg taaaattgaa aaagattttg gtaaaggttc agtaatgaaa
    16621 ttgggagaag caacatctat gtctatagat gttatatcaa caggagcgat tggtttagac
    16681 atagctattg gtataggagg tctacctaga gggagaatag ttgaagtata tggtccagaa
    16741 tcttctggta agactactgt tgcgcttagt tgtgtagcat cagctcaaaa agatggagga
    16801 atagctgcat ttatagatgc agaacatgca cttgacccag tatatgcaaa agctttgggt
    16861 gtggatgttg ataacctaat aatatctcaa ccagatacag gtgaacaggc tttagagata
    16921 gcagaggcat tgataagaag tggagcgata gatataatag taatagactc agtagcagca
    16981 ttagttccaa aggctgaaat agatggagat atgggtgatt ctcatgtagg tttacaagct
    17041 agacttatgt cacaagcact tagaaagtta actggttcaa ttaaaaaatc aaattgtgtt
    17101 gctatattta taaaccagtt aagagagaaa gtaggaataa tgtttggaaa cccagaaact
    17161 actactggag gacgtgcact aaaattctat tcatcagtta gattggatgt tagaaaaata
    17221 gatacaataa aacaaggtga taaagttata ggtagtagaa ctagagttaa agttgttaaa
    17281 aacaaagtag caccaccatt taagcaagct gaatttgata taatgtatgg agaagggatt
    17341 tcaaaaattg gagacctttt agatatagct gctgatgtag atatagttaa aaaatcaggt
    17401 tcatggtata gttacaatga tactaaactt ggacaaggaa gagaaaatgt taaaaaattc
    17461 ttggaagata atttagattt aactactgaa atagatgaga aagttagagc attttacaat
    17521 ttaaatgaag aacatgaaga atcaggtact tcagtatcaa aagaaattgt agaagaataa
    17581 gtaaaaatac aaaaaaataa ctagtaatta aagacatgcc acgctcccta ttagcttgac
    17641 acaatgttga aaaaattata aaattaagtg aggataaaat atctaaattt aattttaatt
    17701 attaggaata ttttttaatc atagtgatga cattttggga ttattaacga aggaggtgga
    17761 tgtcatagat agtgtagtaa tgattgtaat aggtgcagct gttggtatta tagctggata
    17821 ttttgttaga aaaaatatat ctgaagcaaa aattggacaa gctgaaaact tggccaaaga
    17881 aataatagat aaagcacacc acgactcaga aacagtacaa aaagaaaaat tactagaagc
    17941 taaagaagag atccataagt ggagaacaga agctgaaaga gaaaacagag aaagaagaac
    18001 agaagtacaa aagtatgaaa aaagagtagt acaaaaagaa gaagtcttag atagaaaatt
    18061 acaaaattta gaatctaaag aagtaaacct aagtgaaaaa ttaaaggtag tggaaaagaa
    18121 agaagaagaa gttgaagtaa taaaaactca acagttagaa aaattagaaa gtatatcagg
    18181 aattacttct gataaggcca aagaaatcat cttaaccaat gcggagagag atgtaagacg
    18241 tgaaatgtct ataatgataa aagagataga aagtcaagct aaagaagaag ctgataagaa
    18301 atcaagagaa attataggat atgcaattca aaaatgtgca gcagatcacg tagccgaaac
    18361 tactgtaaca gtagtaagct tgcctaatga tgaaatgaaa ggtagaataa taggtaggga
    18421 aggtagaaat ataaggactt tagaaacctt aacaggtata gaccttataa tagatgacac
    18481 tccagaagcc gtaattttat caggatttga tccaataaga agagaaattg caagaattgc
    18541 tctagaaaaa ttaatagcag atggaagaat acatccagct agaattgaag aaatggttga
    18601 aaaggcgaga aaagaagttg acaatattat aaaagaatat ggtgaacaag ctgcatttga
    18661 aactagtgta catgggattc atccggaatt aataagatta ttaggtagac ttaactatag
    18721 aactagttat ggacaaaatg tacttaaaca ttctatagaa gttgctcata tagctggtat
    18781 aatggctgct gaaataggag cagatattag attggctaag agggcaggtt tattacatga
    18841 tataggtaag gctgtagacc atgaaatgga aggtacacat gttgaaatag gtatggattt
    18901 acttagacgt tataaagagt ctaaagaagt tatacatgcc atgagtactc atcatggaga
    18961 ttacgagcct caaacagtag aggctgtatt agttacagca gcagatgcaa tatcagctgc
    19021 tagacctggt gcgagaagag aaactttaga agcatatata aagagacttg aaaaattaga
    19081 agaaatagct aattcatatg aaggtgtaga aaaatcattt gctatacaag ctggtagaga
    19141 aataagaata atggtaaaac cagaagctat aaatgatgaa gaaatacatc tattggctag
    19201 agatatgact aagaaaatag aggatgaact tgaatatcct ggacaaataa aagtgagcat
    19261 aataagagaa acaagagcta tagaatatgc aaagtaaaag aaataatatc taaataataa
    19321 gaaaatattt ttagaaattt aaatttgcca caagatatga taatatatct tgtggctttt
    19381 aaattgttta agtttaattt tatataatgc aaaaataatc taagtgctaa aagtgctact
    19441 tacaaaagat taataaaata aagatttata tatggattat ttatataatt atccaagttt
    19501 gtttgatata atgaagttgt aaaatcaata ctttactaca aaataaatag taaatactac
    19561 agtaaaatct aaaa
//
LOCUS       DAEOTL010000079        19089 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEOTL010000079 DAEOTL010000000
VERSION     DAEOTL010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19089
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.079"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            58..636
                     /locus_tag="KRH82_003054"
     CDS             58..636
                     /locus_tag="KRH82_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8656319.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            675..1253
                     /locus_tag="KRH82_003055"
     CDS             675..1253
                     /locus_tag="KRH82_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8656320.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            1339..1968
                     /locus_tag="KRH82_003056"
     CDS             1339..1968
                     /locus_tag="KRH82_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8656321.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            1958..4717
                     /locus_tag="KRH82_003057"
     CDS             1958..4717
                     /locus_tag="KRH82_003057"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBG8656322.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGRDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            4804..6366
                     /locus_tag="KRH82_003058"
     CDS             4804..6366
                     /locus_tag="KRH82_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBG8656323.1"
                     /translation="MGDSKVFEKIFSNQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            6367..7503
                     /locus_tag="KRH82_003059"
     CDS             6367..7503
                     /locus_tag="KRH82_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBG8656324.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            7567..8643
                     /locus_tag="KRH82_003060"
     CDS             7567..8643
                     /locus_tag="KRH82_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBG8656325.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHFITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIVETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFADALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            8621..9859
                     /locus_tag="KRH82_003061"
     CDS             8621..9859
                     /locus_tag="KRH82_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBG8656326.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENKYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            9913..11001
                     /locus_tag="KRH82_003062"
     CDS             9913..11001
                     /locus_tag="KRH82_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBG8656327.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESMNYIKTIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            11029..11820
                     /locus_tag="KRH82_003063"
     CDS             11029..11820
                     /locus_tag="KRH82_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBG8656328.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYTNIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(11935..12489)
                     /locus_tag="KRH82_003064"
     CDS             complement(11935..12489)
                     /locus_tag="KRH82_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBG8656329.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            12685..13887
                     /locus_tag="KRH82_003065"
     CDS             12685..13887
                     /locus_tag="KRH82_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBG8656330.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            13963..14943
                     /locus_tag="KRH82_003066"
     CDS             13963..14943
                     /locus_tag="KRH82_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBG8656331.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKYILK"
     gene            15191..16144
                     /locus_tag="KRH82_003067"
     CDS             15191..16144
                     /locus_tag="KRH82_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBG8656332.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRANIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            16134..17090
                     /locus_tag="KRH82_003068"
     CDS             16134..17090
                     /locus_tag="KRH82_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBG8656333.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKMLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            17087..17842
                     /locus_tag="KRH82_003069"
     CDS             17087..17842
                     /locus_tag="KRH82_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8656334.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            17934..18899
                     /locus_tag="KRH82_003070"
     CDS             17934..18899
                     /locus_tag="KRH82_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8656335.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDDKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         7566 a         1939 c         3402 g         6182 t
ORIGIN      
        1 aaagataaat aattagcaag atttgtttag ctaaaattaa caagggagcg ataaattatg
       61 ggtataacat tatcaaaagg ccaaaaggtt gatttaacta aaggaaatcc aggtcttaaa
      121 aatattttag taggtttagg atgggatact aacaagtatg atggtggatt tgactttgat
      181 ttagatacag cagcattttt aacaggagca agtggaagtg ttactaatga tggagatttt
      241 gtattttaca acaatttaaa acatacatct ggagcagttg agcatctagg agataacaga
      301 actggcgaag gtgatggaga tgatgaacaa atagttgttg atttatctaa gattcctgga
      361 gaaataagca agatttcttt tactgttaca attcatgatg caacagaaag aagacaaaat
      421 tttggacaag taagtaattc ttatataaga atagtagata aagacacaaa tgaagagtta
      481 ataaagtatg aattaggaga agattttagt atagaaacag ctatagtagt agctgaaata
      541 tataagcaca atggagaatg gaagtttaat gcactaggtt ctggctttga aggtggtctt
      601 gctgcattat gtggaaactt tggaataaac ttataatttc aactataaca ataaactaaa
      661 gggggatatt ttccatggct atagtattaa aaaaaggaca aaaaatcgat ttaactaagg
      721 gaaatccagg tcttaaaaat ataaaacttg gactaggatg ggatacaaat tcatttgata
      781 gtggctatga ttatgattta gatgtaagtg ttttcatggt tggagaatct caaagagttg
      841 aaaaagatga agattttata ttctacaata acttaaaaca tccatctgga gcagttgaac
      901 acttaggtga taatagaact ggtgaaggtg atggagatga tgaggaaata ttagtgaatt
      961 tagagacaat gccaaagcat atacaaaaga tagctgtaac agttacaata tatgaggctg
     1021 ctgaaagaag acaaaatttt ggacaagtaa gcaactcata tataagagta ttaaattctg
     1081 aaaatgatga agaaatatta agatatgact taggtgaaga atttagtata gaaactgcaa
     1141 ttacagtatg tgagatatat aagtataatg gagaatggaa gtttagtgca gttggagcag
     1201 gatttgaagg tggcttagaa gcactttgta gaaactatgg cttaaatgtt taatttaagc
     1261 aatataatat attaaatata aataacctat acaaataatg tataggttat attatataaa
     1321 attttgtgga ggtttagtat gtcgattaat ttatcaaaag gtgataaaat agatttaaaa
     1381 aaatctaacc caggactgag taacatactt gtaggtctag gatgggaccc tgtgcaacaa
     1441 tctggaggag gtttttttaa atcgttattt ggtggaggac aagctgatat agattgtgat
     1501 gcatctgtat ttatgcttaa tcaagaaggt aaattaagtg gaataaaaga tttaatttat
     1561 tttggaaatc taaaaagtgc ctgtaaatca gttttgcata caggagacaa tctaactggt
     1621 gagggtacag gtgatgatga acaaatccta gttaatttgg ataaagttcc atcaaatatt
     1681 cataaattat tgtttgtagt aaatatatac aattgtgtag atagaaaaca acactttgga
     1741 atgatagaaa atgcctatat aagagttgaa gaccaaggta ataagaaaga gatagcaaaa
     1801 tacaatctat ctgataatta ttctgaaaaa actactctta tagtaggagc tatatataga
     1861 aaagatggaa gttggcaatt taaagcaatt ggtgaaggaa caaaagatgc gggtcttaaa
     1921 gaagtaatgc aaaatttaga caggattgag tgtgcatatg gaatttaata atgatatcaa
     1981 atattataat gtagataaag aagaagttac aaaagactta tctgttaatc ctgaaaaagg
     2041 tttatcagaa tcagaagtca agactagaag agaaaaatat ggtttgaatg aatttactcc
     2101 aaaagaagag ggtagttttt gggatgattt aaaggaaagt ttaagtgaac caatgatagt
     2161 tatcttgatt attgcagcag tagtaagtgc agtaattggg gaaactcatg atgcaatagg
     2221 gattgtaggt gctatagcaa taggtatagc aataggtatg attacagaag gtcgttctaa
     2281 gaaagcagca gaggctcttt ctaagttgac tgaaaacata gaagtaaaag tattgagaga
     2341 tggggaagta catcaaattt ctaagagtga attggtacca ggtgatatag tatatattga
     2401 aactggtgac atggtacctg ctgatggtag acttatagaa agtataaacc ttaaaattag
     2461 agaagatatg ttaacaggag aatctgatga cgtatctaaa aagtgtgatg tagtagtttc
     2521 tatggaagag atagaatcta aaggagcagt agtagtacag gagccaatac ctgcaaaaca
     2581 gataaatatg gtgtttggtg gtacacttgt agcttatggt agaggagctc tagttgtaac
     2641 ttcaattgga gataatagtg aaatgggtaa aattgctcaa aacttatcag aaacagatga
     2701 gcaaactcca cttcagataa aacttggaaa tttaggtggt ttgatagcca aagtttctag
     2761 tgcagtagca ggattactat ttatatttat ggttttccaa atgataagta agaatgtatt
     2821 aaatgtagat atgtctggaa tattaccgtt tttagaatca atagacccag ttaaaacagc
     2881 atttacagta tgtgttgcgt tgatagttgc agcagtgcca gaaggtcttc caactatgat
     2941 aaatatgaca cttgcaataa caatgcaaaa aatggctaaa ataaatgcat tagttaccaa
     3001 aaaagaagct tgtgaaacga taggttctgt ttctgtaata tgttcagata aaactggtac
     3061 attaactgaa aatagaatga ctgtagaagt tgcatatgtt gatggcagat atattgaaag
     3121 ttcagaagag gaaataaata gttattttga agaaaactgt atgataaact ctacagctga
     3181 tgtagagcac aatgatggtg atattaagta tttaggaagt gctactgaat gtgcattgct
     3241 tttatattac aaaaacgtag attatagaca agttagaaaa aattctaata tagtagctca
     3301 aaatcctttt acttcagatt caaagagaat gacttctgtt ataggtcgag ataatcatca
     3361 tgtgctatta tcaaaaggag caccagaagt attacttgaa ttatgttcac atattcaaag
     3421 aggaaaagac atagttccat taactgaaaa tataaaacat gagattttag aagaaataaa
     3481 gaaattgcaa ataaaatcaa tgagaacttt agggtttgca tataaagaaa tctcacaagc
     3541 tgaagaagaa gcagcagtaa ctgctgaaag tgatgctatg aatgtaagtg caatggaaaa
     3601 caatttagta tttagtggtt ttgttggtat aagagaccca cttagaaaag atgttataga
     3661 gtctgtaaat acagcaaata aagctggtgt ttctgtaaaa atgcttacag gagataatat
     3721 aaatacagca agagctatag gtgaagagtt aggcctatta aaaaataata tgagagtggt
     3781 tgaagcttca tatatagata ctttagatga tgaagaatta aaacaagaga tacaaagtat
     3841 ttcaatcgtg gcaagaagta aaccagatag taaaatgaga atagtttcag ctctgcaaaa
     3901 gagcggagat gttgttgcag taacaggtga tggtataaat gatgctccag cactttcaaa
     3961 agcagatgtt ggtatagcaa tgggtatatc tggtacagag gtatctaaaa acgcagcaga
     4021 cataatttta actgatgata gttttagtac cattgtaaaa ggtattaaat ggggtagagg
     4081 aatttatgat aacttccaaa gattcgttca attccaatta actgtaaatg taattgcatt
     4141 tttagtggct ataatatctc aagttatggg acaagagatg ccatttacta caatacaatt
     4201 attatgggta aacatcatta tggatggacc accagcacta gcattaggtt tagagccagt
     4261 tagggaccat gtgttaaaca gaaaacctgt tgatagaaaa gccaatataa tttctaagtc
     4321 aatggtgtat acaatagtat taaatgcatt ttatataaca gcaatactaa tgttacaatc
     4381 tacatttaat ttcttaggag ttgatgaagc gcataaggga acagtaatgt ttgcgttatt
     4441 tgcttttagt gcactgttta atgcatttaa ctgtagagag tttaatgcag atagtatctt
     4501 ccctaatttt acacataaca aattagcact acaaataata gtgttgacag gaattgcaca
     4561 agtaatattt actcagctat tccaagattt ctttaactct gtagcaatgg attttatgac
     4621 atgggtaaaa gttttatgtg tagcagcaag tgtaattgtg gttaatgaag ttgtaaaatg
     4681 tataataaga ctggtaaaac caaaaaagac tgcttaaaac aaatttttta gaagaaaaca
     4741 gactgactca aaatatgaat tttgggtcag ttctgaataa acatttaaat tgggaggata
     4801 gttatgggtg actcaaaggt atttgaaaaa atattctcca accaatcaga tagaggaaat
     4861 tacactcctt caaagggata tctaagttat tttatttcgt atattggttt agaagatgaa
     4921 gttttgtaca atctcgagat atttaaaaca aaacaaaata ttgatagcaa aaaagatatt
     4981 gctttattta ctgatgttat agcaaatcct agtgattttg atattataaa ttattttaaa
     5041 agtggacttc aaaaatatag aactagcatg gaagatgtag atataaatat tttgggattt
     5101 gaagagattg attataaaat aaagcaagca atggatagag tgttaaaaga agaggaaaaa
     5161 gaatttacta atgatagagt taaacaaaat tttatagtga aaataatggc atggataaaa
     5221 atttatatcg gtgctttaga tataaataaa aatgaagctc caaaagtaat attttatgga
     5281 gatataaaaa aacatgaagt ttatttactc ttaatattat acttggcagg ttttgatgtt
     5341 ttatatctta atccaaattc aaagagtaat atagatattt taaaatcaga aagatacaat
     5401 atagagtttg aagaagccaa cataatagaa gaaaaaattt cttttgaaga aagggttatt
     5461 ttaggggaaa aaatagataa aagttctgta aaaaaagctt ttactgttgg ggcagaagca
     5521 tcaaagcgta taagtgagga attgttaaat gatgcaggat ttataaaacc ttggcaactc
     5581 caagatagaa aaataaaaaa tctacttcta agttcaactg ttgatgaaat atcaatatac
     5641 tggaatcaac cacttaaatt aagaccagga tttaagttta atgatgctat tgtagaagct
     5701 ccaaattttc tttctaagat taatggaata tataacgata agaatgaata tattaagttt
     5761 ttagatttat taagagattc ggaaagttca acatttattg aatttaatgg agatgtagat
     5821 agattttcaa aagcttttac aagagaagct tttagtttat cctttttatt ggattcaaaa
     5881 ggtgcaatag ataaaaactc tgttttaaat aataaagatt attccatatc aacactagca
     5941 ttgaatcaac aaattatgat tttagagaaa gtggaagagt tgttagaagg aagtatgttt
     6001 ttgaatggtt taagtggaga agacaagata aaaggtctat ttacagtact tcacatggat
     6061 aagaaatttg ttcatatgat gaacaatttc gattactcac ttataaaccc aaaattgatt
     6121 atatacatgt acaagagtat tgtatttgat aaagaaatag tttttcttat gcttttactt
     6181 agtaagattg gatttgatat tatcatatta tgtccaggag gagaaaacaa tatagagaat
     6241 gttataaata accaattgat tgatgtacac agattggata aaatggtata tgaccttaaa
     6301 ttaaattcgc ttgaaaatga tataccttta cttaaaaaaa tttttggaaa gaggagacga
     6361 ttttagatgg ggataaatat aaatagtttt tcaaaagata agaactctgt agaggttact
     6421 gagaatttgc ctacagcagt tcaagaagaa aacttcgata taatggaata tacaaataat
     6481 aaaaaaaatg aactgagaaa gtctaaggaa gttgaggcat tgacatctct tatagaagta
     6541 gaaaatccag atacgatttt acagtttggt aggaaagcat ctgaaggagt agcaagagtt
     6601 tctgatagcc ttttaaatac aataaaatta aatagaaatg aagaaaattc taaaatgctg
     6661 gttcatttaa ctaaaataat ggataagttt gatttagacg attttcaaga aactaaggaa
     6721 ccaaatttcg ttcaaaaact tttcaaaaaa gctaataatg ccattgaaat gatgtttcaa
     6781 aagtatgaaa cattgggagg agaagttgag aaaattcaaa ttgagcttga gcaatacgaa
     6841 agagatatag cactttctaa taagcaaata ggtgctatgt taaatgaaaa ctttgagttt
     6901 tataatgaac ttcaaaaata tattgttgct ggagaaatgg caatagaaga aatggataat
     6961 gaaatactac ctttctttaa acaaaaatca gagactagtg gagatcaaat ggatgttgtc
     7021 aattatcaag aactattaaa agtttatgat atgttaaatc aaagagtcta tgatttaagg
     7081 atagcagaaa atatagctat ccaaacaata cctatgctta gaggtatgca acataataat
     7141 tatggtttaa ttagaaaaat aaatagtgca tttgtcgtaa ctttaccagt atttaaacaa
     7201 tgtttatctc aagctatatt acttaaaaag caagaattac aagcaaaatc tctaaaagca
     7261 cttgatgaca aaactaatga attattgctt agaaatgcac aaaatgtaag tactcaaagt
     7321 gcacaaatag ctagaatggc tggaacaagt tctgttcaaa tagaaacatt ggaaaaaatg
     7381 tacaatacta tcaaatctgg tatagatgaa actatgagaa tagaagaaaa caatagagct
     7441 ttaattaagg ataatacaaa gagattggaa gaattaaata cgactataat ttataataag
     7501 tagtattata ttaagggcta atttgtataa agttggccct ttctatgtat atgaggaggc
     7561 tagacattga aatatttcga ttatatctgc aaagatgatt tagagagaat ttttttgaag
     7621 gagccagaag attttagtgc taagactgaa aaagatgtgt tgaaatatgc actgggcgct
     7681 tttttatacg ttccagctac tcaatataat atgatttata agagtattat aggggatgtt
     7741 aagggagtta gaccattagc tatttgttta gaagatgctg ttggagtaaa tggagagtta
     7801 gaggctatag agaatcttag attaatttta aaaaatatta gcaatgaaag tataactaat
     7861 aaagatggaa taccactaat ttttgtaaga ataaaagatg tggagcaact gttgagaatt
     7921 aaagagatta taattaaaaa tagtcatttt ataacaggaa tattaattcc taaagcaaat
     7981 tcggagttaa ttgaaaattg tatagaagct ttagattcta tgaatcttca agatatgtat
     8041 gttattccga tagtagagac aaaagaattt atatataatg aaaaaaaaga acttagtttt
     8101 actaatttgt acaatgctat tttaagacat aagtcaagaa tattaagcat tagagtaggc
     8161 ataactgata tattagggat gtatggtata aggagagata aaaacttctc tatatataat
     8221 aatttgattt gttcttcatt tatattagat ataatcacat atcttcaaag accagagtta
     8281 gatataccta taagtggtgg agtatcagaa ttttttgata tgacgaataa ggatataaga
     8341 aataagtata tagaagaaat attattggat aaatatcatg gattaattgg aaagaccgta
     8401 attcatccaa tgcaaattca aattgtacaa gcgctatcta cagtatcata tgaagatttt
     8461 gctgatgctt tggatatact ggatagtaca gacagtaagt atggtgtgag caagggtgta
     8521 ttaggagaga gaatgaatga aacaaatcca cattttttat gggctaaaaa aacattgatt
     8581 ctatctaaaa tatatggtgt attaaataaa ggagtagact atgaagaatt gcttaaattt
     8641 taattgtgag attgacatta ttgataatcc attgaattta gaactaaatg attttttaga
     8701 cgtaggaata agaaataata gcaaaagacg ttttttgttt atctcaaaga aactcggtaa
     8761 acatttagca tgtaagccaa gtgagatgga taatttggga aaattaatgg ctacaattta
     8821 taatgaaaaa aataaggaag aatcaaatgg tactgttata gcttttgctg aaactggtac
     8881 agctgttggg catagttttt ttgattactt atgtggagat tatgaattta ttcatactac
     8941 tagagagcag tttgacgagt tagaaaatct ggaattttta gaggaacatt cccatgcaac
     9001 agaccagaat ttatactttg gtatgcttaa caactttaaa tttggagatg agataatatt
     9061 ggttgatgat gagattacca cagccaatac atgcatgaat ataattagga aaattcaaag
     9121 catttatcct aaaaagaaat acactatatg ctcaatactc aattgggtaa gtgatgaaaa
     9181 tttaagtaaa gttactcgtt tagaaagaga gctagattgt aagatagatt ttgtatactt
     9241 atttaaagga aactttaaat tttatataga tgaagatatt atttcaaatt acaacgataa
     9301 ttatagtatt actaaattag agactatttc aagtgataaa gtaaatttag tagtaaatca
     9361 tatttatgtt gatttagaag attatattgg aaataagaaa tatgtaaaat atacaggaag
     9421 atttggaatt aatagaagag aacaatttag attaaaagaa atcgttaaga gagaaagtaa
     9481 aaaaataact atggccagta aagaatcttt aaaaaatgaa aaagaaaaga ttctattttt
     9541 aggtactgaa gaatttatgt atatacctat gctgtttgca aaagaaaaag aaaataaata
     9601 tgatatatac tatcattcaa caacaagaag tccaattatt aatattgata agaataatta
     9661 tcctattaaa agtaaattta tgctaaagag tttttataat atagatattc aaaattatat
     9721 ttacaatata gataaacata atttttctaa gtgttattta tttgtagagc tgaataaaag
     9781 tgaaaattct tatctagaat ttattgatat aattaaaaaa acaagtataa aagaattaac
     9841 tatagtatgt tgtagctaaa gtgttttaac aggataaaat atatcacgat tttaagatag
     9901 gagttgagtc atatgagaga ttttagcacg tattctaaag atgatgttat ttttttatta
     9961 aaagatatat caaatttaat tgaagaagaa ggaaataaag aaagagaatt aaaaatacaa
    10021 aatggtagac attattcaga aatgatacca atagagtatg aagttagtga agattatctg
    10081 aatttatatc atgagaaact aagagaaaat aaagataaac ttgcattttc tataggagtt
    10141 atgtgtgaaa aaataattaa aaaaaatgga aatgatgtag tactagtttc acttgctaga
    10201 gcaggaacac ctattggtat tttggcaaaa agatatataa gaagcaagta taatataagt
    10261 ttacctcact atacaatctc tataataaga gataagggaa tagatatgaa tgcaattgaa
    10321 tatatagtaa agaatcatcc gagctcaaaa attcaatttt tagatggatg gactggtaag
    10381 ggaactatat caaaagaact tgaaaaagca tgtgatgaac ttaatgttaa atttaaaaaa
    10441 tattttgact caacacttgc tgtattagct gaccctgctg gatattcagg actttatgga
    10501 attagagaag atttcttaat accaagtgca tgtttaaatt caaccgtttc tggtttagta
    10561 agtagaactg tactaagaga ggatttaatt ggtaaaaatg actttcatgg agctaagttt
    10621 tatagacatt taaaagataa agatgaatct atgaactata tcaaaactat agaagaatgt
    10681 tttaaaaatc aatttaagaa tatatctgat gaagttgaaa actgggaaag tgacattata
    10741 acaagagatg gatactttga tgttttaaat ataaaagaaa agtataacat aacagatatt
    10801 aactttatca aaccaggtgt aggggaaacg acaagggttt tacttagaag agttccgtat
    10861 aagattcttg ttaaagactt aaatgataaa tctttagacc atatattcat attagctaag
    10921 gagaaaaatg ttgaagttga acaaatggat ttaaaagcct ataaatgttg tggaataata
    10981 aaaaatatga aagatattta ggaaatatat tagacaggag aatattgaat gattgttttt
    11041 tcagatttag acaggagtat catttactcc aataaatttt taaatgctga tagtaaatat
    11101 actaatatag aaatttatag ggaaaaagaa atatcttata tatctttaga tactataaat
    11161 ttaataaagc aaatacaata ttatggtatg tttataccta caactactag aacagtggag
    11221 caatttaagc gtatagaatt taataaatat gggatttatt ttccttggag tataacttca
    11281 aatggaggag ttatacttaa agataatgaa atattgaaat catggagtga aaaaatagat
    11341 aaactaaaat ctgattatga gcccattgaa agtatgattc ataaatttaa agactatttg
    11401 aatgtagatg gaataactaa ttttaaagtt gcagaagata cattttttta tatagttgtt
    11461 gatttatcaa gatttaattt ggattcaatc aaagaatata caaatatatt ggaatcaaaa
    11521 aattggaagt tttatgtgag tggcagaaaa atatatttta taccaaaaga aatttcaaaa
    11581 gaaaatgcta taaaatactt gactaaagaa ttaggaatag aatattttta tgcagttgga
    11641 gattctatta tggactatgg tatgcttaat atctcaaata aatcctatgt attgaagcat
    11701 ggtgatataa ataaaaatga aatagaaaat tcatttatat caagttcttt caatggaatg
    11761 agtggaactg aagagatact atctaacatt ttagacgaga actgcctact taacatataa
    11821 tgactgatat ataaataata aactagaaaa atctgaaata aattatagta aagtttatca
    11881 tactaattta tttcagattt ttatcaattt atatttaagt aagaactcaa tatgttaaaa
    11941 tgaaggtgga gtcattgccc agactgagat acatacctca tcatcataat tttcatacac
    12001 atgtggtata gtactgttaa aataaaaact atctccttcc tccaatagat attccttatt
    12061 tccaagtgtt atcttcattt taccttttat tatatagcca cattcttctc cttcgtgtgt
    12121 cacaaattca ctgttttttt gtgtatgacc atctagcgta acaagtataa attctatttt
    12181 tttcccagat aaattaggaa caagaagttc ataaaatttt gtagaatcat tagttactat
    12241 tttttttcga ttatttttct ttactactat atcagagtct tctcttccaa tctcttcaaa
    12301 aaaataacct atatttatat caagagcttt tgatattttc cacattgcta caatagatgg
    12361 aacaaccata ttacgctcaa tttgacttat taagcctgta cttaaatctg aattttttgc
    12421 taaagtagag atacttatat ttttagattt tctaagagat ctaattttgc ttccaacatc
    12481 tatattcatt agatacaaac cccctcagac atgattataa catataattt ataaagatta
    12541 ataaaataaa aaaaaagttt tacaatacaa gtatttttta tgctatattg aattttctga
    12601 aaagatgcat tataatagta ttaatattca atatattgaa tattgataac gatattttaa
    12661 tttaatgaaa tggaggtaat taagatgaag agttttgtaa gtcctgataa tatttgggta
    12721 ttatgggcag ttgtaactgg atgggcagca tttagtattt atttggaaca aaagtacaat
    12781 tgggcatcaa aagtgtcggg agcaataata gctcttgtag gagcaatgtt attatcaaat
    12841 ctaaatatta taccagtaga gtctgttgta tatgaccaag tatggggata tgttgttcct
    12901 ttagccatag ctttattgtt atatcaatgt aacattaaaa agatatggaa agaaagtgga
    12961 agattgctca ttatatttct tgtaggttct gtaggaactg tacttggagc tatgattgga
    13021 tttttggcat taaaaaatgt agtaccagat ttaaatattg ttgcagctat gatgacaggt
    13081 tcttatatag gtggaaatgt aaactttgct gctatgtcag gcgcgtttga tgcgccagga
    13141 gaattagtat cagcaacagt tgtagcagat aatcttttaa tggcattata tttctttgtc
    13201 ttaatagcta taccatcaat tggatttttt agaaaacatt ttaaacatcc acatgtagat
    13261 gaaatggaaa gtataggtat aactgaagga gaaacagtag cagcaaatta ttggggaaga
    13321 aaagaaatat ctttaaaaga tatagcaata gccattggta gtgcttttat aattgtcgca
    13381 gtatctgtag aactatcaac ttggtttaaa gctataatac cattatcaaa tcctttttta
    13441 gcaatgttaa atactttatt tggaaatcaa tatctaataa taactacttt gactatgttg
    13501 tttgccacat ttatgcctaa tttctttggt gatataaaag gagcacagga attgggtaca
    13561 tttttaatat atatattctt tgttgtagta ggtgttcctg cttcaataac attaataatt
    13621 caaaaatcac cattactact tttatactgc ggaataatgg tactaataaa catgctagtt
    13681 acatttatag ttgcaaaaat atttaagttt agtttagaag aagctattct tgcatctaat
    13741 gcaaatattg gtggtcctac aacagcagca gctatggcaa tatcaaaagg atggtctaag
    13801 ctagtagggc caatacttat agttggaaca tttggataca tagtcggtaa ttattttggt
    13861 cttttagtag gaaatatttt gatataattt tacgtgaaaa aaagttgttt tttagaaaga
    13921 tttttattta ttagaaagat ttttatttaa ttggaggttg ttatgatttt cgatggacat
    13981 tcagatactt gggcagatgt aacaataaga aggcttaacg gggaaaaaga tgtatttaga
    14041 agaatccatc ttgataattt taaaagagca aatatagaag gagctatttt tgtaatatgg
    14101 atagacccac catatgataa agagcctgaa aaaagagtta aacaaattat aagctctata
    14161 aaagatgaaa ttgaagatat gaaagatgtt gtaaacatag taaaaaaata ttcagatata
    14221 gataaaggta taagtgaaaa caaaataaat attttaattg gtcttgaagg attaagccat
    14281 attggaagaa atatagattt actagattat ttttataaag aagttggtgc aagacatgca
    14341 tcattaactt ggaatgaaca gaatgaactt gctacaggat gtttagggga tgaaaatcgt
    14401 ggtttaactg aaataggtaa aaaagcagtc aataaaatgg aaaaattggg catgatagta
    14461 gatgtgtcac atttaaatga aaaatcattt tgggatttaa tgtctgttgc aagtaagcca
    14521 gttatagctt ctcattctaa tgctaggagt ttatgtgatg ctaaaagaaa tcttacagat
    14581 aatcaattaa aagaaatttc aaatacaggt ggattagttg gaataaatag ttttagagga
    14641 tttactaata gtaatcctaa gaagcaagat ttaatacatt tggttgacca tatagactat
    14701 atggtaaatc ttataggtat agaacatgta tcttttggtt ttgattttag cgattactta
    14761 gggaaagaga ctataggttc ttttactgga aatgctagtg tgccaagtgt agatggtctt
    14821 gaaagcacac atacagcaca gaacatagta gtagagcttg aaaatagagg ttataaaaag
    14881 aaagatatag agttaatctc tagtggtaat ttttataggc tctttaaata tatactaaaa
    14941 taatataata aagaacttaa atttataaaa tagtatattt atacaaataa tatctacata
    15001 tttaaattgg cgttcataat ttattaaatt aaattttaat gttactagaa gtttcaattc
    15061 tagtaacatt ttttatgtta aaaacagata tagatatgta ttgacaatga taattattat
    15121 tgataaacta taaaagtgaa aatgataata attttcattt taattaataa aagattttta
    15181 aggagggaga atgaagaaaa ggtatttagt cataggaata ataattttgt cttatttttc
    15241 tttatttata ggagctgaag atataaatat aatgcatata tttgccaaaa atcagcataa
    15301 acttatgata tttatcatga gtagaatacc aagattaata agtatattga ttgctggtgt
    15361 aggaatgagc atagcaggtc ttataatgca acagataagt aagaataaat ttgtatcacc
    15421 tacaacaggt gctacaatag atgcagcaca atttgggata gtaatatgta tgcttttagt
    15481 accaactgcc tctattttta caaagacaat aatagcattt gtattttctc ttgtagggac
    15541 ttttacgttt atgaaaataa tagggaagtt acaatttaaa aatataatct ttgtaccatt
    15601 agtaggtata atgtttggaa atataatagg ttctatgacg gattttatcg cgtataaata
    15661 cgatttgagt caaaatgtta gttcttggat gcaaggtgac ttttctatga tacttaaagg
    15721 aaattatgag atattatata tcacaatacc ccttataata ttagcatata tttatgcaaa
    15781 taaatttact gttgttggta tgggtatgga ttttgcgaca aacttaggtc ttagttacaa
    15841 aagaattgtc aatataggtc tgataatagt agcacttgtt acagtatgtg tagtcgttac
    15901 agctggtaat atccctttta taggtctaat agttccaaat atcgtatcct tgtatatggg
    15961 tgataatata agagcaaaca tatggtatac tggtttactt ggagcgatat ttgtacttat
    16021 atgtgatatt tttggaagaa ttattattta tccatatgaa atatctatag ggcttacagt
    16081 tggagttata ggaagtatac tattccttta tttaatatta aggaggaatg taaatgaagc
    16141 ttagtctcaa tcaaaaaatt tactttgtaa gtatattact attcatatca atagcacttt
    16201 ttataattta tggaatagac atgaatcatt tagaatatgc attatcacaa agaataccaa
    16261 aaatatttgc tatggtatta ggtggaggat gtatagcatt tactactgta gtgtttcaaa
    16321 caattacaaa caatcaaata ttaacaccaa gtgtactagg tttagattca ttgtatgtaa
    16381 tgattcaaac tataatagta ttcatatttg gttcaagcag tagtctgatt ataaatgaaa
    16441 attataattt tattattaat gtagctatga tgattggagc ttcattgtta ttatataaga
    16501 tgttatttga aaaaaataaa aataatattt tctttttaat cctagtagga atgatatttg
    16561 gaaccttatt taaaagtgca acaacattta ttcaggtaat gatagacccg aatgaatttt
    16621 tagctttaca aactagtata atggcaagtt taaacaatat aaacactaat gtattgttaa
    16681 tagcatttat aataattatt gccataatac cttttatata tgatgaaata aagtatttag
    16741 atgtattgtc gttaggtaaa gaacaagcaa ttaatttagg tgtagatttt gataaagcag
    16801 ttaaaaaaat gataatatta atagcaattt tagtctcaat atcaacagca cttattggac
    16861 ctatgacatt tttaggactt ttacttgcta atataacaag agaaattttt aaaacatata
    16921 agcatacata cttgatttcg ggttctatgt tgatagggat gattacattg ataataggtc
    16981 aattttttat acaacatgta tttaagtttg atacaacttt aagtgtagta ataaatttta
    17041 taggaggaat ttactttatt caattactat taaagggggc aaatagatga tagagataaa
    17101 aaatatattt aaaagatata agaataaaaa tgttgtagat gatgtctctt ttagtataga
    17161 aaagggaaag ataacatctt ttataggacc aaatggagct ggaaaaagta cagtactatc
    17221 aatagttaca agacttatag gaggtgatgg tggagaagta ataatagaag gaaaaagctt
    17281 gactaattat agcaataaag aattagcaaa aaaaatagct attcttaaac aatctaacaa
    17341 tataacttta aagcttacaa taagagaatt agttggattt ggaagatttc catatagtga
    17401 aggtaatcta actaaagagg atgaaaatta tattgatgaa gcaatagaat atatgaagtt
    17461 gactgatata caacataagt atttagatga attgagtgga ggtcaaagac aaagagctta
    17521 tatagcaatg gtaatagctc aagatacaga gtacatatta cttgatgaac cactgaacaa
    17581 tttggatatg aaccattccg tacagatgat gaaggtactt agaagtcttt gtgatgagtt
    17641 agataagact atagtattag taatgcatga tataaatttt gcatcatgtt attcagataa
    17701 tatagttgca ttaaaaaatg gaaaagttga aaaagtaggt cgtacagatg agatagtaaa
    17761 tgaaaaagtt ttagaagata tttatgagat gaattttaac attaagaata taaatggaaa
    17821 tcgaatctgt atttattttt aaaatattgt atatgaaaat aaacttgcta tataattttt
    17881 tataaagttt ttaaattaaa ataaagatta ataggagaga ggaaaatatt gatatgaata
    17941 aaaaagcagc aatagtagca gcagtagcta ttataggatt agtgacagtg tttgcattag
    18001 gtggaagtaa aaagaatgaa tcaaaaacat cagaaaattc aaataatacc ataaagataa
    18061 ctcataactt gggagaaaca gatgtaaaat taaatcctaa aaaagtagta gtatttgatt
    18121 attcggcttt agatacaatg gatgcattag gtgtagctga gaatttagta ggacttccaa
    18181 aagcgagttt accagcatct ttagaaaaat ataaggatga caagtatgca gatttaggag
    18241 gattaaaaga accagattta gaaggtataa agtcggcaaa tccagattta attataataa
    18301 atggaagaca agaagatttt tatgagcaat tgtcaaaaat agcaccaaca ataagtacaa
    18361 gtaaagatga taagaagtac ttagaatctg ttaaaaataa tatagacaaa atagcaaaaa
    18421 tatttggagt agaagaaaaa gcaaatcaag aatttagtaa aattgaaaag aaaatagaaa
    18481 ctttgaataa aaaagtaaca gataaaaatt taaatgcttt aactataatg gtaaatgaag
    18541 gtaatttaag tgtatttggt gaagaatcaa gatttagtat attatacaat agttttggat
    18601 ttgaaaataa agataaaaat ataaaagaat caagtcatgg acaaaatatt acttttgaat
    18661 atatagctaa acaaaatcca gaagttatgt tcgttataga tagaggaata gctactggca
    18721 gtgatgtaaa agaaagctca actgcaaaat ctgttttgaa caatgatata ataaaatcta
    18781 tggatgcata taagaatgat aatataatat atttagattc accaacatgg tatgtaaatg
    18841 atggtggtct aacatcttta aataaaatga tagatgatgc ttcaaaagcg gtaaattaat
    18901 aatccgatat aaccaaaatg tattttttat aaaatgatta tcaaataaac taggagtttt
    18961 taagaactcc tagtttattt tttgcataaa aaagatatag tttaaacaat aatattatct
    19021 ataataagat aaatctattc aaaatctaat aaaatatgaa gttatactag acaaaaagaa
    19081 taactctta
//
LOCUS       DAEOTL010000080        18555 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEOTL010000080 DAEOTL010000000
VERSION     DAEOTL010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18555)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18555)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18555
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.080"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            204..1364
                     /locus_tag="KRH82_003071"
     CDS             204..1364
                     /locus_tag="KRH82_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBG8656336.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1706..1867
                     /locus_tag="KRH82_003072"
     CDS             1706..1867
                     /locus_tag="KRH82_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656337.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2060..2689
                     /locus_tag="KRH82_003073"
     CDS             2060..2689
                     /locus_tag="KRH82_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBG8656338.1"
                     /translation="MKIVTYNIHKCMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            2928..4187
                     /locus_tag="KRH82_003074"
     CDS             2928..4187
                     /locus_tag="KRH82_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBG8656339.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4446..5441
                     /locus_tag="KRH82_003075"
     CDS             4446..5441
                     /locus_tag="KRH82_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBG8656340.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5687..6754
                     /locus_tag="KRH82_003076"
     CDS             5687..6754
                     /locus_tag="KRH82_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBG8656341.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFVEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7288..9198
                     /locus_tag="KRH82_003077"
     CDS             7288..9198
                     /locus_tag="KRH82_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBG8656342.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9261..9884)
                     /gene="ytaF"
                     /locus_tag="KRH82_003078"
     CDS             complement(9261..9884)
                     /gene="ytaF"
                     /locus_tag="KRH82_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBG8656343.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10072..10716
                     /locus_tag="KRH82_003079"
     CDS             10072..10716
                     /locus_tag="KRH82_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656344.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
     gene            10930..11988
                     /locus_tag="KRH82_003080"
     CDS             10930..11988
                     /locus_tag="KRH82_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBG8656345.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            12092..13276
                     /locus_tag="KRH82_003081"
     CDS             12092..13276
                     /locus_tag="KRH82_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBG8656346.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKGDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            13483..14196
                     /gene="rpsB"
                     /locus_tag="KRH82_003082"
     CDS             13483..14196
                     /gene="rpsB"
                     /locus_tag="KRH82_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBG8656347.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            14275..15186
                     /locus_tag="KRH82_003083"
     CDS             14275..15186
                     /locus_tag="KRH82_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBG8656348.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            15271..15975
                     /locus_tag="KRH82_003084"
     CDS             15271..15975
                     /locus_tag="KRH82_003084"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBG8656349.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            16001..16558
                     /gene="frr"
                     /locus_tag="KRH82_003085"
     CDS             16001..16558
                     /gene="frr"
                     /locus_tag="KRH82_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBG8656350.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            16561..16764
                     /locus_tag="KRH82_003086"
     CDS             16561..16764
                     /locus_tag="KRH82_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656351.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            16793..17527
                     /locus_tag="KRH82_003087"
     CDS             16793..17527
                     /locus_tag="KRH82_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBG8656352.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            17540..18319
                     /locus_tag="KRH82_003088"
     CDS             17540..18319
                     /locus_tag="KRH82_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBG8656353.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         7623 a         1854 c         3227 g         5851 t
ORIGIN      
        1 aaagatttta aattcagatt attcatttct aaagtaatta atgtgcaaat ctttattaat
       61 atatgtcaat agttaggtat atatgtattt aattagtatg atatagataa aagtatttat
      121 tttaattgtc tattatctga aaaagtcttt acttagaaat cataaaaatc aaattaatta
      181 ggaaaagaaa gggtgtgtat aatgtgattg agactggatt tgtatattgt agtttcttgg
      241 ttgtattcgt aggtgtaatt ttttttatgg ttgataaatt gaaatggaag gtatttgatg
      301 ttattaatcc aatgctttta atatacttag gttcagctat acttggatca tttggtttat
      361 ttgcacagaa tgaagatgtt ggaacgtatc aaaacataat aacagtgaac ttccttccat
      421 taatgttagt gtttttgtta attcaatgtg atttaagaaa aatattaaag atggggccta
      481 aaatgttatt atcatttttc tgtgctacat ttacatttat gcttggattt gttatagcat
      541 tcataatttt taaaaattca atgggtgcag attcatggaa aattcttggg gcagcatctg
      601 gttcatggat aggtggctca tcaaatatga ttgcagcagc taatgctcta ggagttgcag
      661 aagaaggact tagttatgca atacttatgg gttctatagg atatacagta tggatgtctg
      721 tttgtctaat gtctgtgaaa tttggaccta aatttaacaa atggacaaag tgcgatacaa
      781 gttttataga tgaggttaca tcaaaacttg aaaaagaaaa taaagataat acggcaccta
      841 cgtttgtaga acttatgatt ttactttctg ttgggtttgg agttgcgtct tttgcacaaa
      901 ttgtatccaa gatacttcca acttcaggta tacttaatga aactatgtgg gtagtacttg
      961 ttgcatctac agtatcaata ttattgggta tgacaaaaat atcaaagctt aaagggagta
     1021 cactggtagg aaatgtgttt atgtatttac tccttgcagc tacaggtagt aaagcaaatt
     1081 tctttggatt gtcagaagca cctgtttaca taatgtttgg attggtagta gtccttgtac
     1141 atgctatttc atttataggg cttgctaaac tatttaaact tgatttattt acttgtgaag
     1201 taggaagtat agctaatata ggaggagtaa ctacagctcc aatgattgct ggggttcaca
     1261 atcctgtatt aataccagta ggtgtactta tggggcttct aggaaatatt atagggactt
     1321 attgtgctct tatggtaact caaatattac atatgttagc ttaataaaaa tatggtataa
     1381 aattaataat ttaaataaga aaagtcattt caatttaagc agaagctttt actgaaatgg
     1441 cttttttgtt tgacaagata atctatttca agaagatgtt ttgacatatt tagtgtataa
     1501 tattgtaaaa tttactaaaa acgagatata tttaattttt atattgaatc gaacgtctgt
     1561 atgatgtata ataaatatac agaacgaatg tttgcagaac gggtgttttt tgaatttatt
     1621 ttaataattt atgaatatat atcagaatgc ataaatatat ttaaatataa agattaaaaa
     1681 gaatttaaag gagtgttgat aacttatgat aattccatca agaagaatac aagatataac
     1741 attaacaaat ttaaaaaatg gtgaagtaac tttaattgaa ttggatgaaa tatacaagaa
     1801 gatgggattt ttatttgttg ttagtgaagg caaattgaaa aagataaaaa aggagaatca
     1861 tcattagaaa tgaatgaaat aataaatatt ataatagttt ataaaaccta acttatgtag
     1921 aatataaata cttaagttag gtttttttgt gataaagttt ataagtactc aattttataa
     1981 gataaataat ggtcttaagt gaaaagtaaa taagtttaaa ttttagtaag tattatattg
     2041 cataagaggt gatattatta tgaaaatagt aacctacaat attcataaat gtatggattc
     2101 aaataataga ttaactctaa ctaaaatggg gttatattta aaacaattgg attgtgatgt
     2161 aatttgtttg caagaagtat tatatcctca atttttagct ttaaaagctg ttttaaatat
     2221 ggatggtgtc tttgcgacaa atgtaaaaaa agtaaatatg atatatggta tttgtacatt
     2281 tacaacatct aaaatgttaa acagtaatca ttttttctta actagcaaaa aagaacaacg
     2341 gggagctctt tgtataacta tagatgcata tggaagaatt ataaatgtaa taaatactca
     2401 cttgggactt gataggcagg agagagcaaa acaattagac gaaataatag actataggaa
     2461 cagattagtg gggatagtta ttttatgtgg tgattttaat gagaaaaatg tctttttaag
     2521 tatgtttaat gatatggcta tttcactaaa caagtcttac ttaccaacat ttgaaaaatc
     2581 aaactctaga atagattaca tttttgttaa taaaaatact gaactaaaag gatacacagt
     2641 agaaaaaatt tacctgtcag accattatcc tgtaataggt tacatttaaa tttcaatata
     2701 aatgaaatta gttgttataa aataaacaat tttttgttaa gaaatagtaa aagaaatata
     2761 ataaaaaata tcaaaaataa aactaattat aagacataaa tttacaataa agttacattt
     2821 gattaaattc cttgtttaac aaaagctatt caaatataat ctaaggtagt tttgaaatgg
     2881 gaactctatt atgcaaattt aagctagtgt taaaatgagg tgaagttatg ggcagaagaa
     2941 caacaagagt ttcaagatta ggtaaagaaa aaaaacgaag tgttttaatt gtattggcag
     3001 ctttagttct aataatgggt ggatttactt atttttttaa cagtaaattt ctgtacaatg
     3061 ggaaaatcgc taaaaatgta tatatagaag gagtaaatgt atctgatatg actaaagcag
     3121 aggcattaaa agctataaca gataagtata ctccagaaga tttaaatctt gcttatgatg
     3181 ggaaaaaata tacaatatca ccaaaagata ttgatttaaa atatgataca gaagatgttg
     3241 taaaagatgc ttatgaaagt acaaaaaaag ggtcctattt tcaaaactta aaaaaatata
     3301 ttgatataag agtgaataag gcaaatatga agataaaagc tgaatatgat gaggcaaaac
     3361 ttagttccaa agtgtcttct atagcagata gtataaatgt taagatgaaa aatgcttcta
     3421 ttagtgttgg aagtggtgga ctaagttata cagactctgt tgtaggtaga gaatttgatt
     3481 tggcagcaaa taaagagtct atatataata tgataaaaaa taaagagcat aaaactttag
     3541 aacttaaagt aaatcttcaa aaaccagata taacaactga acaagtaaaa actgtaaatt
     3601 ctgttatagg tcaatattca actacttatt cacaagctgt agagggtagg tcatataatg
     3661 taggattatc agcaagaaaa actagtgatg tattattaat gccaggtgaa gaattttcat
     3721 acaataaact tacaggacct agtaataaag caaatggtta caaagatgca cctgttatag
     3781 tttatggtaa gctagaacaa tcagcaggag gaggtgtttg tcaaacatct tcaacagttt
     3841 ataatgcggc tcttctttcg ggtatggaga taactcaagt tacaaatcat tcatctgcat
     3901 ctacttatgt gcctaaaggg agagatgcta ctgtgagcga tggaggatta aacttaaagt
     3961 ttaaaaatcc atataagcat cctgtatata ttaaaaatta tgcaggtgga ggaagtgtat
     4021 catcagtaat ctatggtaat tctggtgaca aaccaaatat atctatagag gtaaaacaaa
     4081 ctggtcagaa taaatattct acatatcgaa tatttaaaga ttcaagtgga aaggtcataa
     4141 aaaaagaaca tatatcaaat agttcttata aagaattaaa aaaatagata attttttaga
     4201 gaaatatttg taatataaaa gggagtgtct caaaatgaac tttttagttt atgaggcact
     4261 ctttttctgt gaaatcaaat atattttcat catttcaaca atacaaaaga agcgtatctc
     4321 tattttgaga cagccttttt tgtaaaaatt aacactatta gttcttgttt taatattaca
     4381 atcattaata tatagaaaat attcctatat attggtataa ttgtaaatag atttagttat
     4441 ataaaatgta tgaggaggtg acatggttga attttatagg caatagatat gaggtagtaa
     4501 attctgacga cgttttagaa attaacaaaa tctataaagc tagagatgtt ttttacagga
     4561 aaaatgtgtt aataaaagtt ataaagcaca ataattatat ctgtgaagat tttgtttcaa
     4621 atttaattga tgaaagtact gctttagatg agataaactc tccttatata ctaaaaataa
     4681 tagatgttgg gattcactgt acagaagaaa caacattata ttatgttgta agtgaagact
     4741 ttaatggtat cggactagat gaattaattc taggtaatta tcttcattta gaagcaattg
     4801 taaacataat gatacaagtt ttaaaagctt tagaaatgat acataggaat cattcatatc
     4861 atggtagttt aaaatcgagt agtataatag tagatacaga atacaatata aaaatttgtg
     4921 attttggaat tacaaaagca aataatgggg ttaatacaag aagctatgga aacaggagat
     4981 atttatgccc acatcaacta tgtataaatt atactgataa agaaagtgat ttttttgcaa
     5041 caggtcttat tctatttgaa tctatattta aaaaattgcc ttttggagaa tcaaattcag
     5101 aagaaaaaat gctacaatct attgataagg gattagattg gaatagtata aaagcaatta
     5161 atggaaatac tgaacttata aatgttataa aaaggcttct tggaagaaat aataagtata
     5221 ccagagccaa tgatattatt attgatttaa gtaaagtaat gtatgaaaaa gcatatatag
     5281 aagttgaaga tgagaaagaa gaagagcaga aacaagacaa agttatacaa gttaaaaaag
     5341 aatataaaag taaaatgaga aaaaaattac ataaaaaact tgttgttgcc ggtctagcta
     5401 tagtcatgat ttcaatgatt attattagtt ccataatata aaaattgtat attaagtatt
     5461 ttaaaatcaa tgtctataaa ggatatacat agaaatttta gtgtagtctt aaattatgaa
     5521 aggaagtggt tattatgtta acaaaaaata atgaggtatt aaacgtctag gagtatttta
     5581 acaaatagcc acctgctttt acagtttaga ataaaaaagc tgtggctaaa ggtcacagct
     5641 ttttgctact ttttaaaggc aggagaatat taaaaaggag caaattatga gcaatataaa
     5701 aataatagca agtaataaat gttggattga agatatagca aggaaacaac ttgaagatat
     5761 ttcaaagtta aatggaattt taagagtagt aggattacct gacttacatg caggtaaaat
     5821 acctgtaggt ttagcagttg agactaaaaa tattatttat ccacatataa ttggaaatga
     5881 tataggatgc ggaatgactt tatttaaaac tggagttcta aaaaagaaat ttaaaaaaga
     5941 caaatggatt aagtcactta gtaagattaa agatttgtct gatatagaaa taaaaaacac
     6001 atataaagaa gaatgtccaa ttttaaattt aggaactata gggagtggaa atcattttgt
     6061 agaaattcaa tgtataagtg aaatttataa taaagaacaa tttgaacaat taaaattttc
     6121 atctgatgat attatgatgt tagttcactg tgggtcaaga aattatggag aagatatttt
     6181 aaaaaaattt tatgataaag atggacttga agttgaaagt gagaaagcta tagattatat
     6241 taaaaaacat gataatgctt taatgtgggc agagcgtaat cgtgaagcta tcagtaaaaa
     6301 aattatgcag tcaataggta catctggaga tgttgaaaca atattctcta taaatcataa
     6361 ctttgtagag aaaagggaag ataaatttat acatagaaaa ggtgctgttt caagtgaaag
     6421 aggagctgtg attataccag gttcaagagg cagtctatca tatatagtta tgcctactga
     6481 aaatacagag atatctttat attctctatc acatggagca ggtaggaaat ggtctcgttc
     6541 agtttgtaaa tctcgcctta aaagtaagta tagtaaagat actataaaac aaactaaatt
     6601 taaaagtcag attatatgta atgatgtaaa tttattattt caagaagctc cagaggcata
     6661 taagaatata gagcagatta ttgaaagttt gatagaatat gaacttattc aagtagtggc
     6721 aactatgaag ccattgatta cttataaagg ataattttta aagttaaaaa agattaaaat
     6781 tatattataa atagctaatt ttatggaaca tttaaaagtg ttttattatt agctattttt
     6841 ttattttgta gagacgataa tttatagagc taaattcttt gatatataat gattacaaag
     6901 ttagactgta ttggaaactg cacatacatg aattgatgac aatataagtg attccaaaat
     6961 ataaatgaaa gtataagctt attttcacta taaaaatttt cactgtacaa aaacattaat
     7021 gacattattt ttattgacat aaatatataa tttatggaat aatattagaa gcactgatat
     7081 aagtgtttaa ataaggatag aaaaggagaa gtgttttatg aaaaaaaata ctaacattaa
     7141 tgagtccgga gttaaacttc ttaataaata aggagtttga tatataataa ctccttattt
     7201 attaagttgt tcgcaaaata actattatca aagtaaatga tagggtgatt taaaagacga
     7261 taacttataa ataaaggaga aaaaataatg aatagtaata catttgaaag attacaacta
     7321 aatgaagtta aagaattaat aaaaatacat tgtgtaagtt cactaggaaa aaatttaata
     7381 gataaattaa ctcctagtgg gaatattgga gtagtaagaa ggaaattagc agaaaataaa
     7441 gaagctagaa agataattga aaatagtaat cacataccac ttgaaggatt gtttaatgca
     7501 ggttctacaa tagataaaat tgaaaaagga atgataatag aacctgttga acttgtaaat
     7561 attgaagatt ttttaagagg ttgtaggaag atgaaagctt ttatgttaga aaaagaattt
     7621 tattcaccta cattaagttc ttatgcctta aatataacag aatgtaaaag tatagaagat
     7681 gagataaatt actgtataaa atctaataaa gttgattcta atgctagtaa agaattaaaa
     7741 aagataagac gaaatataga aattacagaa ggaaagataa aagatagatt aaataaattt
     7801 ataacatcaa ctgtaaataa aaagtatata caagagttta taataagtaa aagaaatgat
     7861 agatatgtaa taccaattaa atcttcttat aaaaatgaag ttaatggtac tatattagat
     7921 acatcatcaa aaggaaatac tgtatttatt gaacctatta gtgtttcaaa tttaagtaca
     7981 gagttaacta tgctaaaagc tgatgaaact attgaagaat acaaaatatt atcttattta
     8041 acagaactta tatttgagaa gataagtcag ataaaattaa atatagagat actttcagaa
     8101 tacgatatgg tatttgcaaa agctaagtat agtcaaaaaa taaaaggaat tactccaaaa
     8161 ataaataata atggctatat aaaaataatt aaaggtaaac atccacttct aacaggagat
     8221 gcagtacctt tagattttga aataggcaaa aattatagaa gtcttataat aacaggtcct
     8281 aatgcaggag gaaaaactgt aacccttaag actgttggtt tactaacttt aatggttcaa
     8341 tgtggatttg atatttctgc aaaagaaggt agtgaattta gtgtatttga aaaagttttt
     8401 gtagatatag gggataatca aagtattgaa aatgccttaa gtactttttc atcacatata
     8461 aaaaatattg cagagattat gagtttatca aataattcta ctcttgttct gtttgatgaa
     8521 ataggaagtg gaactgaacc taatgaagga gctggtttag caatatcatt attagaagag
     8581 ttttacaaaa tgggatgtat aactatagca tcaactcatt atggagagat aaaaaagttt
     8641 gctacattgc atccagaatt tgaaaatgct ggtatgatgt ttgataaaga aacgttagaa
     8701 ccattgtata agttaactat tggaaaatct gaagatagta atgctctttt tatttctaaa
     8761 aaaatgggaa taaaaaatag agttttagat agagctaaag aatatgtaat tgatagaaac
     8821 tacaatttag atttagttaa aagaagtaag ctacaatcta atattgaaga taaaaatagt
     8881 tctgaagtca ttttaaacta tacagattat aatgtagggg ataaggtaaa attactagat
     8941 gaagatgatt ttggaattgt atataagcct atggacaagt ttaataatgt agaagtattg
     9001 tttaatgata attttatttc agtaaatata aaaagattac aacttagcat aaaagcatca
     9061 gaattgtatc cagaagggta tgatttagat gtattattta ctagttttaa agaaagaaaa
     9121 ttagaaaaag atattcaaag aggttcaaaa aaagctctta aaaagattca gaaagaaatt
     9181 agagagaata gaaaataaat ataaaaagca caaaagaaag caatctaaag agaaaagttt
     9241 atctttagat tgctttctta ttaacatatc ttcataaatc caatgactaa caagattaaa
     9301 ccacttaacc aagataagtt taaatttacg tttttaacaa acatatttcc tagtaaacaa
     9361 ccaagtaata ctgcaattat atttgatatt aaagaaaata gaataacttg tatataattc
     9421 acacctacaa ggccactacc aaaaccgata gctaatccat ctaaacttaa agcaagtgca
     9481 agtgtaaatg cttcagcaga tttaagcact ttagatttac ttgtatctaa gacatcaggt
     9541 tcgatactta cattaaaatt taatttaagg tctaacatat taaaattata attctttgag
     9601 tgtatagatt ttttcttaaa ataagattta aaaaaacttt caattagtct agcacttcct
     9661 aataaaaata aaataaagaa acatattaac attgttatat tttgaggtaa aaaatctcta
     9721 actattgtac ctgcaaaaag cgatattgct aaaatagctg aacaaactac gctgataatt
     9781 atatttgaat ataagggaac tttaacttta tttacaccat atccaaagct tgtcacaaag
     9841 gcatctatac aaagagaagt aactaataaa attgattcaa tcacagtaga ttaacatcct
     9901 ttctcttaaa ttttgtactt atattagtta tagtattgta aaaatggata aattgttaca
     9961 gataatccaa taaattgttg ataaaattcc aacatcatac aacacctaaa taacaaaaga
    10021 atcatatcat ataataatat aaaaccaatc ataataaagc gggtgaaaat aatggaacaa
    10081 aataataagg ttgggaattt cggtgatttg ttgaagattt tattagatga aaaagaatta
    10141 tcaatgggag aactaagtaa aaaaagtgga attgataaat ctactatatc tcgtatagct
    10201 aataataaac aaaagccaaa tataaatcat ttagaaaaga tggcaataca tttaaatatt
    10261 aacctagaag aactgttgaa agcttcagga tatgaattta gaaacagcaa taatcaaata
    10321 tttaatgcag atagtgattt tagtaacttt gatgatattc ttggatttgc aaatttaatc
    10381 aatgataaga actttaatgg aaatattgaa aaagagttaa gtaagtgtaa gttatatgtc
    10441 caaacagatg aaggtaaaaa attacttttt gataatttta ataaaaaaat agattctatt
    10501 gaaaaacaag gtcaatttac agatagatta agacaaatgt atgctgattt ttgtacagat
    10561 ggacttacaa taaagaaata tttattgatt ggaagtatgc tactttactt tgttatatca
    10621 acagatgtga ttccagactt cgtgttccca ataggattta tggatgattt agtagcatta
    10681 aatatagtta caaaattact taaaaatgat aagtaagttt tagaatcata tttaatatat
    10741 aaataaatca aagtatataa aatttattat tttttatatg aaacaaatta aaagcacaat
    10801 gaagtagatt aaaaatttaa aactaagaat ctaatatata ttttgtaact atttaagtat
    10861 ataaaataaa ataatatcca aactaataca aaatagtaat aattgttttg tactggagga
    10921 tatatattta tgaattgtaa atggatatct aaaatagatg agagaaaaaa atgtcataga
    10981 gaagcagatt cttctggata ttgtatcttt cataaagaaa ataagtctga tgaagagata
    11041 cagttgatga tggatactct tcataaagaa gagataagtg aatttaatgg atttgttttt
    11101 gaaaatgaat ttaatgcgga agaaatatta acttacaatt ataaaatact ggatttttct
    11161 gaatccatat ttaaacaaaa agcaaatttt aaaaaatata tttttaaaaa gaatattatt
    11221 tttaactata cagaatttag agataaagtt ttatttaatg gttgtgtatt cttagaaaac
    11281 tgtgatttta atagaaccat atttagtaaa cactatataa atgaccgtat atttgaaaaa
    11341 gtgaaattta aaggacctga tttggtagtt aataaagtag aaaattttcc acgaatggat
    11401 ggaataattt ttagcatgtg tacaaaattt gtgttaaaga atgttgaata tggaaaaagt
    11461 gagtatgagc atggcaagat aaattataga atagctagaa atcaagcaac aaaaattgga
    11521 gaatatgaga tgataggatt ttactattat aaggaaagaa tttatagtag taaaataatg
    11581 aaacgttcta attatcctac tttcagtgat tatttagttg aaaaattttt tgaccaaata
    11641 gcacgttaca caacaggtta tggagaaaag ccatggaata tattattagt tattatagca
    11701 ataataagtg tttttgcttt attatactta tttgtaggca tagaaagttc aaatagcaca
    11761 cttgtagctt tagatataaa taatataggt gattactcac taagtgagat tttcaaaatg
    11821 tatatggatt tatggtattt tagcatggct acatttagta cagtaggata tggagatatg
    11881 gttgctacaa gtttgattgg gaaagcattg gcaggtatag aagtattttt tggagttaca
    11941 ataggagcaa tttgggcatc tgtgattatt aaaagaatga taaggtaata tttgtgtaaa
    12001 tatggatagg tattaattac tagatataaa ttggactaaa tagggaaaat ttaaatataa
    12061 atatacttaa taatccaaga aggtgaaaaa tttgaaaaat gcactaaaaa aaattatatc
    12121 attagccatg attctagttt ttataatacc aaattattca tatgcagatg ataaatctgt
    12181 agacaagtat tcaaaaacat ctatacttat agaccaagaa acaggtagag ttttatatag
    12241 taaagaacct gatatgaagg taccattagc tagtttaagt aagatgatga cttttttact
    12301 tgcaatagaa gctattgaaa ataaagaagt aaaagaaact gataaagtaa aaatagacaa
    12361 atctattgca tcagtaaaag ggtcaagtta taaacttaaa gatggtgaag aagtgccact
    12421 tatagagctt atgagaggtc ttatgattgt atcaggaaat gatgcggcaa ttgctatagc
    12481 aaaacatatt tgtaaaacga aagaagcatt tgtagataga atgaataaaa aagcaaaaga
    12541 aataggaatg agtaatacac attttctaaa tccaaatggt cttccaatat acgatttaag
    12601 caaccccaaa aaaccagcaa aagaaaatat ctctactgca aaagatatag ctattcttgg
    12661 aaaatacatg tttgaccatt atgaaaaaca agtaacagct ataactgata tggagacata
    12721 tacaaattca gatagaagtt ttgaaaaaag caatacaaat gcattattaa gaattatacc
    12781 agaagtagat ggtataaaaa ctggatatac tggcaatgct ggatattgct tatcattttc
    12841 tatggttgta aataaaaatg ataaaaatga gaaaaaacgt agagtaatag gggttgtatt
    12901 aggtactaac cataaaaata aaagaacctc tgcttcatta gctctactga aatatggaaa
    12961 agaaaatttc aatatgaaaa aagtaattga taaagatagc tttattggta agaaatatat
    13021 aaaaggaatg aaagagttag aggttacatt aaaagcaaaa gatgaacttt atacaatatt
    13081 aaaaggtgat gaaagtataa aatcagaagt taagattaaa aatatagagt accctgttaa
    13141 aaaaggtgat actatgggta ttataaaata ttatactaat tcaggtgact tacttggaag
    13201 tgtagatata gtaagtaata atagtataga taacgtatca ttaaaaacaa aattaaaaat
    13261 gaaatttgca aattaaattc aaaaaatggt ataaaataca caaaaaaata taaaaataga
    13321 aaatatggaa aaaatattgt tatttcttca cctctgtgat atactactag aggtgaaaaa
    13381 ataaaataaa tcacacacag cattgggatc cttaaaaggt gcctattaca tggtttttta
    13441 gggagaagat caagctggag gtataaaacc aggaggtaag atatgtcagt aatatcaatg
    13501 aaacaattat tagaagcagg tgttcacttt ggtcaccaaa caagaagatg gaaccctaaa
    13561 atggctaagt atatattcac agagagaaat ggaatatata taatcgactt acaaaaaaca
    13621 gttaaaaaag ttgaagaagc ttacaagttc actaaagagg tagctgaaac aggaaagcca
    13681 atcttattcg taggaactaa aaaacaagct caagatgcga taaaagatga agctgaaaga
    13741 tgtggaatgt actttgttaa tgaaagatgg ttaggtggaa tgttaacaaa ccacaaaact
    13801 ataaaaacaa gaataaataa attaagagaa ttagaaaaaa tggaagaaga aggcgtattt
    13861 aatgttcttc ctaaaaaaga agttataaaa ttaagagctg aaaaagaaaa actagaaaaa
    13921 tacttaggtg gaataaaaga catgcctgaa ttaccaggtg caatgttcgt agttgaccca
    13981 agaaaagaaa acatagctat tcaagaagct catagattag gtataccagt agttggtata
    14041 gttgatacta actgtgaccc agaacaatta gactttgcta taccaggaaa tgatgacgct
    14101 ataagagccg taaaattaat aactggtgct atggcaacag ctgtaattga aggtagacaa
    14161 ggtgctgagg aagaagtagc tgaagaccaa gaataataat ttgacaatta aatggtaagg
    14221 gtcgccctta ccatttataa tatggaatag aataagtagg aggaaactta aaaaatggct
    14281 aatataactg ctcaaatggt aaaagagtta agagaaagta caggcgcagg aatgatggac
    14341 tgcaagaaag ctttacaaga agctgaagga aacatggaaa aagcagtaga tttattaaga
    14401 gaaaaaggat tatcaaaagc tgctaaaaaa gctggtagag ttgctgctga aggtctagtt
    14461 gcaatagaaa tgaatgatga taatacagtt gcttctatgg tagaagttaa ctcagagaca
    14521 gatttcgttg ctaaaaacga agacttcaaa gtgttcgtta aagatgctgc ttgtatggca
    14581 ttagctactg ataaagaaga tatagcttct ttattaggtg aaactcataa agagggaata
    14641 actttacaag aagttttaaa taatagagtt gcaaaaatag gtgagaaatt agactttaga
    14701 agatttgcta aagttgtaac taatggacaa gttgctggat acattcacgg tggtggaaaa
    14761 ataggtgttc ttgttgaaat ggaaacagaa gctagagatg ctaaagtttt agaattaggt
    14821 aaagatgtag ctatgcaagt tgctgctatg aatcctaagt atgtttcaag agatgaagta
    14881 gatgctgaat acatagcaca tgaaacagaa gtattaactc aacaagcttt aaatgaagga
    14941 aaaccagcta atatagttga aaaaatggtt aaaggaagat tagaaaaaga attaaaagag
    15001 gtttgtttat tagagcaaac tttcgttaaa aatccagata taactgttaa acaattagtt
    15061 gctgatgttg ctaaggcagt aggttctgat ataaaagttg ttaaagttgt gagattcgaa
    15121 gttggtgaag gtatacaaaa gagagaagaa aactttgcag aagaagttgc taagcaactt
    15181 aagtaataac caaagagaga acacgcaggt gttctctttt ttaaaaaata gaaaaaattg
    15241 gatatgaagg attgaaatag gaggtttctg atggataaac caatgtacaa aagggtattg
    15301 ttaaaattaa gtggagaagc attagcagga gaaagaggtt ttggtataaa taatgatgta
    15361 gttaatgata ttgctattgc tataaaaaaa atacaagaaa taggtgttga agtagctgta
    15421 gtagtaggtg gaggaaactt ctggagaggc agaaccagtg aaggaatgga cagaactact
    15481 gctgactata taggaatgtt agctacagtt atgaatgcaa tggcgctaca ggatgcacta
    15541 gaaaatatag atgttgctac aagagttcaa actgctatag acatgagaca aattgcagaa
    15601 ccatatataa gaagaagagc agttagacac ttagaaaagg aaagagttgt tatatttggt
    15661 gcaggaacag gaaaccctta ctttacaaca gatacaactg ctgctttacg tgctgctgag
    15721 atggaagcag aagttatatt gttagctaaa aatgttgatg cagtatatga caaggatcca
    15781 aaagtacatg cagatgctaa gaaatttaca gaattaagtt acatggaagt tatacagaaa
    15841 gaattaaaag taatggattc tacagctaca tctttatgta tggataataa aattccaata
    15901 aaggtatttg agcttacaac agagaatata ataagagcag taaaaggcga aaatatagga
    15961 actactgtaa aataatgaag aatgaaggag gagtaaaatt atgaaactgg aaatacataa
    16021 gcaattagaa gagaaaatga atgggacaat tgatgcttta aagtttgaat ttggaactat
    16081 aagagcagga agagctaatg cacaaatgct agacaaaata agagttgatt attatggaac
    16141 tccaactcca ataaatcaaa taggtgctat atctgtacca gaaccaagaa tattaatgat
    16201 atctccttgg gataaatctg ctatgcatga aatagaaaaa gcaatagcta actcagactt
    16261 aggattaaat ccatcaaatg atggtgaggt tataagactt tctgtacctg ctttaacaga
    16321 agaaagaaga aaagaattag ctaaaaaagc tagtaaagct gcagaagaat ttaaagttag
    16381 aataagaaat gaaagaagag acgccaatga gaagattaaa aagatggaaa aaggcggaga
    16441 attaactgaa gatgaattaa aaaaagcaca agatgaagtt caaaaaatga ctgataaatt
    16501 tataaaagaa atagatacat tattatctaa aaaagaaaag gatataatgg aggtataata
    16561 ttgaaaaaat attataacct tttaggtctt catgtagatg aggtaaaaca atattttgat
    16621 gagcaaaata taaattatac cgtaaaatct attgaaggta aaaaggataa agaaaaactt
    16681 gtagttccta gagttataaa aatatctgag ataggtgata gtgtagaact gataatcaca
    16741 tacttttctg actccttagt ttaaggagtc agaacaatat tggaggcaaa atatgaataa
    16801 caacattata tatgatatag acttaaataa catacctact catattgcta ttataatgga
    16861 tggaaatgga agatgggcaa aagctagatt tcttccaaga actgcaggac ataaggctgg
    16921 agtagaaact ataagagata tagtaaaaga atgctcaaaa ttaggtgtta agcacttaac
    16981 attatatgca ttttcaacag aaaactggaa aagaccgaaa cttgaagttg acacacttat
    17041 gaacttatta tctacatact taagaaatga aatagctgaa cttcaccaaa acaatgtaaa
    17101 agtaactgct ataggagata taagtgcttt accaaaaact tgtataagag aattaaactc
    17161 agctaaggaa ctgacaaaaa acaatacagg agttaactta aatttagcat taaactacgg
    17221 aagtagagca gatataaaaa atgctcttat agatatagta aaaaattgtg aaagtggtaa
    17281 aatagatata aacaatattg atgaagatat tataaaaaac tatttaagca caaagtctat
    17341 accagatcca gacttggtaa taagaacaag tggtgaacaa agattgagta actttttact
    17401 ttgggaagtt gcttattctg agttttactt tactgatata cattggcctg attttaaaaa
    17461 agaagaacta cagaaggcta tatacgtata tcaaagaagg gatagaagat ttggaggact
    17521 taagtaagga gattatttta tgcttacaag aattattgct tcactagctc tggttccatt
    17581 atttctattt gttgtatatg gaggtattcc tctatatata gctgagacag caatagttta
    17641 tattgcattg catgagtttt ataaggcatt taaaataaaa gatgtacatc caatattcat
    17701 tataggatat ttattttcta tttatttagc tgtaaaaaat atttttaatt taccattaga
    17761 atatacttat gcagtaattt ttattttatt tttagcaagt ataatttata tgttgatggg
    17821 caaaaacaat gttatagatg tttcgattac gtttttagga gttttttata taggagtatt
    17881 tttagatttt ataattataa ctataaatgg atttgaaaaa ggtagtatat atgtatggct
    17941 tatatttgtg atatctttta tgacagatat atttgcatat tttagtggtt atttacttgg
    18001 aaaacataag ctaattccta aagttagtcc taaaaagact atagaaggag ctattggagg
    18061 aataatagga agtacacttt gttgtatttt atttggatat ttatttggca ttgatttgct
    18121 tcaattagcg ataataggaa gtataggaag tgtaatagct caattaggag atttatttgc
    18181 atcttctata aagagatatg tagggataaa ggattatgga aagataatac ctggtcatgg
    18241 gggtatatta gatagatttg atagtgttat attagttgca ccttttgtat atagtgcgat
    18301 taaatttttt attagataaa gattggttgg atttaaaaga gcaatctata attgctagta
    18361 atgaaaatag ctatgtaact tttaaatgca gagatattct gcagttatta gttacatggc
    18421 tattttcatt gttcaaaaat ttagaagacc ttggggaatt gtataagaat aggtattact
    18481 ttataatagt atactatatt tgtagtgagt atatttttta tactataact atcattaaaa
    18541 aatatttttt tgttt
//
LOCUS       DAEOTL010000081        18499 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEOTL010000081 DAEOTL010000000
VERSION     DAEOTL010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18499
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.081"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            205..1422
                     /locus_tag="KRH82_003089"
     CDS             205..1422
                     /locus_tag="KRH82_003089"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBG8656354.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1517..1897
                     /locus_tag="KRH82_003090"
     CDS             1517..1897
                     /locus_tag="KRH82_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBG8656355.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2181..2663
                     /locus_tag="KRH82_003091"
     CDS             2181..2663
                     /locus_tag="KRH82_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8656356.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2684..3499
                     /locus_tag="KRH82_003092"
     CDS             2684..3499
                     /locus_tag="KRH82_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8656357.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3552..5102
                     /locus_tag="KRH82_003093"
     CDS             3552..5102
                     /locus_tag="KRH82_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBG8656358.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5199..6551
                     /locus_tag="KRH82_003094"
     CDS             5199..6551
                     /locus_tag="KRH82_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBG8656359.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGLHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6682..7440
                     /locus_tag="KRH82_003095"
     CDS             6682..7440
                     /locus_tag="KRH82_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656360.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNN
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7487..8206
                     /locus_tag="KRH82_003096"
     CDS             7487..8206
                     /locus_tag="KRH82_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBG8656361.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8330..9730)
                     /locus_tag="KRH82_003097"
     CDS             complement(8330..9730)
                     /locus_tag="KRH82_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBG8656362.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9734..10642)
                     /locus_tag="KRH82_003098"
     CDS             complement(9734..10642)
                     /locus_tag="KRH82_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8656363.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10903..11550
                     /locus_tag="KRH82_003099"
     CDS             10903..11550
                     /locus_tag="KRH82_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBG8656364.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11875..14514
                     /locus_tag="KRH82_003100"
     CDS             11875..14514
                     /locus_tag="KRH82_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBG8656365.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14572..15675)
                     /locus_tag="KRH82_003101"
     CDS             complement(14572..15675)
                     /locus_tag="KRH82_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBG8656366.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16035..16856
                     /locus_tag="KRH82_003102"
     CDS             16035..16856
                     /locus_tag="KRH82_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8656367.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16935..17146
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17233..>18499
                     /gene="argH"
                     /locus_tag="KRH82_003103"
     CDS             17233..>18499
                     /gene="argH"
                     /locus_tag="KRH82_003103"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBG8656368.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDF"
BASE COUNT         7057 a         2142 c         3283 g         6017 t
ORIGIN      
        1 aaaaaatatt tttaaattat catttaatgt aatttaaatg aattgaagat atatgtttat
       61 tgtatgcaat tgttgtattt ttaggttttt tgtgattaat taaaaaatta taaaaatcgt
      121 ttacatgttg atttttaaaa aaaaaagata tagaattata tagaaagtaa taaacaaaaa
      181 ttggatttac gggagtggaa tgaaatgatg aatgttacct taacagatgt aaaagaggct
      241 agagagacca ttaagaacat agtaaaaaga actgacttac ttgaaagtgt taaacttagc
      301 gaaaaaacag gagcaaatgt gttctataaa tgtgagaatc ttcaaaaaac aggttctttt
      361 aaattaagag gagcttgtaa caaaatagcg agtttaacag atgaagaaaa ggcaaatgga
      421 gttatagctt caagtgcagg gaatcatgct caaggagttg cattgggagc aaaaatgact
      481 ggtataaaat ctacaatagt aatgccagca actgcgcctt tagcaaaagt tagtgcaact
      541 aaaggttatg gagcagaagt agttttaaat ggtgcggttt atgatgatgc atatgcaaaa
      601 gctgttgaaa tacaaaaaga aacaggagca actttcttac atccattcaa tgataagtat
      661 gttatagcag gacaaggaac tatatctctt gaaattttcg aacaattaga caataaagtt
      721 gatactatac tatgcccagt tggtggagga ggaatcatct ctggtgttgc tgttgcagca
      781 aaagcattaa atcctaatgt aaaaatagtc ggtgttcaaa ctgcaaatat accttcaatg
      841 aaagagtcaa taaaaaatgg aaaagtaaca acagcattta atgatactac aatagctgat
      901 ggtatagctg ttaaaactcc aggagattta acttttgaaa taataaatga attggttgat
      961 gaaatagtag tggttgaaga gacagaaatt gcagaatcaa tattatttat gatggaaagt
     1021 caaaaaatag tttcagaagg tgctggtgct gtatgtacag ctgctatatt aagtggtaag
     1081 tatgtaccag caaaagatga aaatgtagtt tgtataatat ctggtggtaa tatagacata
     1141 aatacgttat atagaataat aggtgttgct ttagctaaag aaggaagaag atattcattt
     1201 agtacaatta tggaagataa gccaggaaac tttgctgagt taactagaat aataagtgag
     1261 aatggtggaa acattttaag tgctaatcaa ggtaaattat cagcagggga agctctagga
     1321 aaacaaagtg cggaatttat attagagaca atagattatg accatatagc tagaataaag
     1381 aaagctatag aagaaaaagg ttttaaaatt atagaattat aataaaaagt gtatataata
     1441 tacaagaaaa atagtataat agtgtatgaa gatacatttt atgtgtatta gattaacgaa
     1501 ttaggaggat tttaaaatga aacatgaagt aatacatact aatgatgcac cagcagcttt
     1561 aggaccatat tctcaagcta taaaagctgg aaacttgtta tttgtatctg gacaagttcc
     1621 tcttgtacca gagactatgg aagtagttga aggagatgta caagctcaaa ctgctcaatc
     1681 tttaaaaaat cttaaagcta tattagctga aagtggagct gatttttcaa atgtagttaa
     1741 gactacagta tttataaaag atatgaatga atttggggct ataaacgaag tttatgctga
     1801 atattttgga gaaaataaac cagcaagagc ttgtgtagaa gttgctagat taccaaaaga
     1861 cgttaaagtt gaaatagaag taatagctgt attataaaaa tacaatattt ttaatttgaa
     1921 aaggctgaaa aactatattc tagtgattca gcctttttat aaaaaaataa atcacaataa
     1981 agaacatgat aaatattgtc gaattaaaaa ataaaattaa aataaatatt gcaatatttt
     2041 tgagaaggtt ttataatgag tatataattt gaaacgtgta actattaaat taggcatgag
     2101 ttcttggata tttttatcct gaggattcat gccttttttg tattgaaatt caaaaatcta
     2161 tttaataagg aggaagtact gtgttaaatt ttttcaagaa aaataaaagc tataagttac
     2221 atgcagtagt gagtggtaac agcattaata ttgagaaagt aaacgattct gtgttttcaa
     2281 aaaagttaat gggagatgga gttgcaatta ttcctaatag tgatgttgtt gtagcccctt
     2341 gtaatggtaa agtaactgtg cttacagaat caaagcatgc ctttggtatg gtctcagatg
     2401 agggtgttga aatattagtc cacataggaa ttgatacagt tagtttacag ggtgaggggt
     2461 ttaaaaatga agtgtctcaa ggagatactg ttaaaaaagg tagtccaata ataagttttg
     2521 aaagagaaaa aataaattct cagggaattg attgtacaac aataataatt gtattaaatc
     2581 atagcgaatt ttcagaaata aattgcatgg tagaaaatga agttgttgca gggcaagata
     2641 ctgttattga aattatgaaa taataggaag ggattaattc aatatgagag tagtaaaaat
     2701 ctttaataat aatgcattat ctacagtaac taatgatagg aaagaagcta ttttactagg
     2761 tcttggtata ggttttaata aacgtccagg agataaagtt aatgaagata aaatagaaaa
     2821 gatttattat gttcaagacc acatgcaaac aaaattttta gaattattaa aaaatgttag
     2881 tccagaagtg atggatgctt cacaacaaat tataagtctt ataccaggaa atgagggaaa
     2941 atttaataat aaagggatat tatctttagt ggaacatatt agttttgcaa tagatagaat
     3001 gaaaaataat gtttttttac ctaatttaat gcttttggat ataaagatga tgtattcaaa
     3061 agagtttgaa ttaggagtaa aagctttaga aattatatat agagtatgtc atatccattt
     3121 gcctgaagat gaagcaggtt acatagcttt acattttgtc aatttacaat caaatgataa
     3181 tttggcatat gatactttaa aatttgtaaa aggtagtatt gatttgatta aagaatgtta
     3241 tggattagaa ttagacgaat cgagtttaag tacattacgt tttagaactc atcttaaatt
     3301 tcttgctcaa agaattttta agaatgaaat ttgtcaggat gataaaatga ttgaaatgta
     3361 tgattattta attaacaatc atcctaaaaa taaagaatat ttagaaaagt taaatgtata
     3421 tattgaaaag gagtttaggt ataaattaga taaacctgaa aaaatttatc tactactaca
     3481 cctaacaaaa atcttataag aatgagatga attagtaata gaaatatata taattttagg
     3541 gggggataag attgaaagaa aaactacttg gaggactgga aacatttgca aaggcaatgg
     3601 ttcagccatt aatgtattta tcgagtgcag gaatattaat ggtggtaggt gtactactta
     3661 caaatgatat gttattagga gtacttccat tttttaaatg ggagccaatt caaatatttg
     3721 gaagcctaat ttataactgt ataatggcta ttattaataa tcttgctgtt atatttgcta
     3781 taggtattcc tgctgcacta gcaaaaaaag agaagcacaa agcagcgtta ataggattta
     3841 tgagttatat aatatacctt acagcttcca acactatgtt aacatcacta ggtcaactag
     3901 caaaagaaag caagatgctt ggactgatag ggactggaca agctactatt ttaggtattc
     3961 aagttgtaga tacaagtgta tttggtggaa ttattttagg gtgtatagct ggatatgtat
     4021 ttaatcgtac aagcaacaaa acatttaaag gagctttaca gatatactcg ggagcaaatt
     4081 ttagttttat atgcatgttc tttgtatcca ttttaattgg agttgtgagt aactttatat
     4141 ggccattagc tcaacaagga atagcttctc ttgcaaatgt catcaaagat acaggtacat
     4201 ttggtttatt cttatatggt tttttagaga gaatattagt accaactgga cttcatcatt
     4261 taatttatac accatttcag ttttctgatt taggaggagt gcttaaagtt ggtgcagata
     4321 cagtttcagg agcctatgct atagttatga cagaaatgaa tttaccagtt gagcgtttct
     4381 cagatagtat atactatatg gcaactggat ttacaaagat gtttggttat ataggtatag
     4441 gagctgcctt tatttatact gcatataagc aaaataagaa gaaggttaag gcaacgatta
     4501 ttccactaat aattacagca gtattagcct ctgtaacaga accattagac tttatgtttg
     4561 tattctgtgc accactttta ttctttgtac atgcagttat agctggtctt tttatagctt
     4621 tattaaaaat atttgatgtt actgcattat gtggagggaa cttattagta tcaattataa
     4681 tgaatactac agtaggcgta gaaaaaacac actggccagt aatgatgata ttaggacttg
     4741 cacaaattat tgtatatttt gtagtattta gttttttaat taagaaattt aattataaaa
     4801 ctccaggtcg tgaagatgag agtacagcta caggcgaaga acaatcaaaa caacttaatt
     4861 tagatgcagg gatagaaaat ataattgatg ggttaggcgg aaaagaaaat attaatacag
     4921 tagaaaattg catcactaga ttacgtgtta atgtaaaaga tgaaagtaag attaatgaag
     4981 atataattaa tttaacgcca aatagcggga ttgtaaggaa aggaaaagat atacaaataa
     5041 tttttggact tcatgtgcat gaggtaagac gtgcagtaga agatttttta gaagcttatt
     5101 aaagatatat atttatatag caagggtaaa taacagcttt aagtgctgtt tactatttat
     5161 taaagataca tataatttat agaggaggaa taattattat gattattact attgttggtg
     5221 gaggaagcac atttactcca ggtattgtta agtcaattgc attaagagaa aaagagttag
     5281 agcttgagga aattcgttta tttgatattg ataaaaaacg tcaagataaa gtagctgtag
     5341 ttgtcaactg gatactaaaa gaagatgtta aaacagatgt taaactaact gtaactaatt
     5401 gtgaaaaaga agcgtataca gatgctacat ttatatttgc acaaatgcgt gttggtaaat
     5461 atgaaatgcg tgagcaggat gaaaaaattc cattgaaata tggttgtgta ggtcaagaaa
     5521 cttgtggttg tggagggatg gcatacggac tgcgtacaat acaaccaatg ataaaggtta
     5581 ttgatgatgt agagaaatat gctaaaaaag attattggat attaaattac tctaatcctg
     5641 ctgcaatcgt ttctgaagct tgtcgtaagt taagaccaaa tgcaaggatt ataaatatct
     5701 gtgatatgcc aatagctatt atagatatga tagcggggtc attaaatatc aatgacgttc
     5761 ataatatacg ctatgattat tttggtctaa atcattttgg ctggtttact tcaatagatt
     5821 ataaacatag agacttaatg gaagagatta aggaatacat aaaagaaaat aaaatattat
     5881 taccaaaatc ttatatagaa aacttaaata aaagtcgtag tacaggaaat cgccatgctg
     5941 taagtagctg gatacatgtt tgggaatctg tttatacaat gttagaaagc ttcccaaaat
     6001 atctgccaaa cacttattta acatactatc ttttaagtaa agaaacagtg gaacattcaa
     6061 acataaatcg tactcgtgca aatgaggtta tggaaagccg tgaaaaagac ttatttgaag
     6121 gtgtgagaca ttacttagaa actggagaaa tttctgaaaa agcattttat gcaggtttac
     6181 atggagattg gattagtgat ttggcagttt caattaaaaa tgatacacgt agtcgttttt
     6241 tagttataac tgaaaatcgt ggagctatac caaacatgcc atatgatgca atggtagaaa
     6301 ttccagcata tattggtaaa gatggtccag aagttattgc tcgaggtcca atacctctat
     6361 ttcaacaagg attaatgatg caacaactta acagtgaaaa attgatagta gaagcttata
     6421 tagaaaatag ttatgaaaaa gctttacaag cattcacatt aaataaaact attccaagta
     6481 tgaatgttgc taaagaaatt ttggatgaaa tgatagaagt taataaggaa tactggccag
     6541 aattaagata gtaggataaa agaaagggtt tttatttaat cattagatat gttttcagag
     6601 tcttttatca aaatgtattc acaaacatat ggcaatatat taaaataaag agtgatattt
     6661 ttagaagaat ggggtgatgc aatgaacatt ataaataaaa ttttttggca agaagatagg
     6721 attggcatga ttacaaataa tttagaggca gatacacata gtcactgtat gttacaactg
     6781 ttcttaggga tagaagacag cattgaaata acagttaatg aaaaattagt taaatgtaat
     6841 tgtatcatag tagataaaaa tatctctcat tcattttcag caagaaaaaa agtttattac
     6901 tctgctatta ttgaacctac atctatatat gcagaacagc ttacctcaaa aatgaatgat
     6961 tttggctact ggatatgtga caataatgga ttagagaaat tacgtcaaca aggaactttt
     7021 ttgatagata actctagtaa agaacaatat ttaagattta tggaaatgct taataactat
     7081 ttgaatatac ctataactct aaaacattat gatgacagaa ttactgaatt gctcaattta
     7141 ttacgtactt gtaattgtga taatcatact atttcaagtt ttgcagataa agtgtctcta
     7201 tcagcaagta gattatcaca tctgtttaaa gaacaaatag ggataccttt aaaaagctat
     7261 atcttatttc atcaaatgga gtgtgctttt agagaattac tttctggaaa aaatgttacc
     7321 gaagcttcta tgactgctgg attcgatact ccatcacact ttgcagggac agttaagcga
     7381 atgatgggaa tgcctgtttc tttatctttg aaagatagcg agtttttgaa agtatattaa
     7441 atattctcgt tatataatga agttgtacta agaaaggggc tttgttatga ataaagaata
     7501 tttagaagaa acaaaaatgt taaattataa tgaaccacaa cttaagcttt tggtatcatc
     7561 aaagaattgg ttggaattag atgattttca taaaataaaa tctatttatg agtttgtaca
     7621 gaatgatatt ttatttggat ataatgcttc tgatatgtta agcgcaacac aggtattaaa
     7681 tgatggtatg ggacaatgca atacaaaagc tactctttta atggcattat tacgtgcagt
     7741 gaatatcccc tgtaggcttc atgcttttga tgtaacaaaa gattttcaac gaggagctac
     7801 atccaaattg atttcactat tagcaccaaa atatattctt catacttggg tagaggtatt
     7861 ttatcaagat aggtggattg ctctggaggg tgtcataact gataaaaaat atttagaagc
     7921 aattcagaag aaatttttta atcatggtgg aacgtttaaa aagtatgcaa tagctacaaa
     7981 tgatttgaaa aatacatcta ttgattggga tggtaaagat acttttatcc aaaaagaagc
     8041 tatcgtgtat gattatggta tttttccatc accagacgta tttttttcta ctcattcaca
     8101 acatatgtca aaattaaaaa atttcatata tgtacatctt atcagaaaaa taatgacaaa
     8161 aaatgtatgt aaggctagaa acaattatat tgataaaaat gaatgagtgt ttaagaggta
     8221 actatatagg aaatatatag aataattaaa actgtactgg ttaaaatgaa taaaaaggag
     8281 ttatcacaga gcaaacttaa attgttcata ggataactcc ttttctgtat taacttctaa
     8341 taatttgatg tctttttata aaacatatag atacaattaa accagtaaat gcaagagtag
     8401 ctgctattga aaatgcaaca tctattccat gaatgttaga cagcatgttt gaactcatat
     8461 gagctttctt agtagcactt gtcattatag taataagtat agcagaacct atagctccag
     8521 atatctgacg gagtgtgtta ttaattgctg tggcatgaga tataagttct ctatctaatg
     8581 ttttaattcc ccatgtagtt aatggcatta aaaccattga aataccaatc atacgaatac
     8641 aatacatcaa tgacacatga attaaagatg tatctctgcc taaaaaagcg aaggataaag
     8701 ttcctaaaaa caaacatcct gttcctaata ttgatagagc atgaggtcca tatttatcta
     8761 aatgacgtcc tgcaattgga ttgagtacaa ccatcaatat agcaccaggt aacattaatg
     8821 aacctgaaga taatgcagaa aatcctctta cagattgaac gtacagagga atcattaatg
     8881 tagcagacat cattgaggca tatacaatca taattaatat tgtagaaata agaaatggtt
     8941 tatttttaaa aaccctcaat tctaaaaaag gttctttaga ttttaattga cgcaatgtaa
     9001 ataaaattaa tgacataatt cctattaata ttggtaaata tgtggcaata ttagtccacc
     9061 cataattacc ttgattagta aatccaatta ataaaccacc aaaacctaga gatgatagta
     9121 ctattgaagg tatatctaat tttagttttt gagtttcccc aacatttctt aataaaataa
     9181 atgatagtat aacatctaat atagcaatag gggaaagaaa cagaaataaa ctatgccaac
     9241 caaatgaatc tactaaccat cctgataaag ttggacctat tgctggagca aatcctactg
     9301 taataccaac taaactcata gctgcaccac gtttttcctc agggcataaa tagagtataa
     9361 taacttgtaa aagtggcatt agagaaccag aacccattgc ctgcaacaca cgagcaatca
     9421 acatagttga aaaattatta gaaaaaagtg caataataca tcctatagaa aagatagaca
     9481 ttgatgtaat aaataacttt ctagtactaa atcgatttat taaataagct gttgtgggta
     9541 caataatacc tgcaataagt agataaattg ttgttaacca ctgaccaaca tcagcagtaa
     9601 ttttaaaatc tgacattata ttaggtaatg ctgttgacaa tagtgtttga ctgagagaac
     9661 ttataaaagc accagtcatt acaattgcta ttattaaatt tcctttttta ttgttacttt
     9721 gggtttccat aatttataac gtctcctttt ttaattgatt tttaatgctg ttcaataaaa
     9781 gtacttttgg tcttaaagtg tcttcttttt ctaaatatgc aatcattgca tccataatta
     9841 aagaatcata ttgttgattt tttccctcga cgtataattt ttttattgct tctagtaatt
     9901 taggattttc aaggagagaa gtatccgttt tgattagttc ttctatatct tgtatcgttt
     9961 taaaaaatag cgatttatta tgaagggaaa agtaaacttc atcttcttgt ttatgtaaaa
    10021 acattgattt ttcaattaaa ggatttagat tatccatatt ttctacaact aaatctagaa
    10081 tttgtatagt aaatttggca ataaagtata catttatttc tcttttttgt acatgaataa
    10141 tgtatataaa ctgatgaatt agagcatcca ataagaaaac taaatcaaat ataatttttt
    10201 ctattttatc accatagtta tcaaataagc ttagtttgta ttcattcaat aagttagctc
    10261 ttgattttgt ttgcaattta cttgtagcct tacgttgctc ttcagaaaag ttttctctta
    10321 tataggtatt tatggtagtt ctagaaaaaa tatttttcca tacagcaatt atctttctgt
    10381 ttaacttttc tgatgatgga atgtcattat tttcatttat ggaatgtata atttctaaaa
    10441 acttttcatc ataataattg attatttcgc agataaaact ttccttagtt tcaaaatgct
    10501 tgtaaaaagt agctttagac attttacact cttttacaac atccgatatt gaagtatttt
    10561 gaaaaccttt ttggtcaaaa attttttgtg caatagttat aatgagcctt tgtttttctg
    10621 tcactttatt atctcctttc acgcaaaaac gtttagtact atatagtacc tacaagtttt
    10681 gataaatata ttatacatca tttggaaaaa aaatcaatat atagactgta atatgaaatt
    10741 tttgaaaaat ttgttgttat ttttagtcgt ataaaaaaga aacttaagag tttcttaaga
    10801 attgtttaaa gaagttgcaa taaattagtg gtatgattat agtatgaaag agaatgtctt
    10861 gaaatttttc tgtatcaaat tccaattatg gaggtgtagt atatgaaaaa gaaaatttgt
    10921 gtagcaataa tttttgctct atttatagtt tttgtagaaa tgtttattga tagctctagc
    10981 gaaggaagta aaattatgac agctgaatta agtaaataca ggaaaggcgt aaatgtatta
    11041 tcaataaaca atattatagt agcgaataaa aaatatagtt tgcccaaaga ttattctcct
    11101 caggaaagca gtgaagcgag agatgctttt tataaaatga ataaagatgc tcaaaagtca
    11161 ggattaaatt taaaagcttt tagtacatat agaagttatg aatatcaaga tagattattt
    11221 aagtcatatg taaaagaaca tggagaaaaa gaagcaaata gattttcagc taaacctgga
    11281 gagagtgagc atcaaactgg acttgctttt gatattggag gagatgacca gtcttgttgg
    11341 gcaaataaaa agttcaacaa tacaaaagaa gctaagtggt tgtatgaaaa tgcatataaa
    11401 tatggtttta tacttagata tccagaaggt aaagagaata taacaggata tatgtatgaa
    11461 tcttggcact atagatatgt tggaactgaa catagcaaaa actttgcaat gaataatttg
    11521 actttagaag aatatttaca tataaattaa gagatggttt gttaaaatta ggttaaaata
    11581 aaaaataacc tagactatta gctgtgtaaa gtgatataat gtaaatacaa tttaagataa
    11641 ctactcgaag gggagtagct tacacgaaag tggtaattaa tcgtcaagac agtagaaata
    11701 ctcggttaat tagcaaggga ttccttgata gcaagacctt caaaataagc attaggtatg
    11761 tttgttttgg ggtctttttt tattcaagga atttttattt aaaaaaattt aaatttcaag
    11821 tatacataag agcccccaaa cataaaataa atttattgaa gaggagggca acaaatgtct
    11881 tacaaaagta cttatcaaga agtaattaaa aatttagact caagtttatc tggtttgagt
    11941 aaagaaagag cagaagagtt gttagaaaaa aatggagcta atgaattaaa agaagcagat
    12001 aaggttccta cttataagct tttcctagaa agttttaaag acccattagt aataattcta
    12061 ttgatagctg ctttagtaca aatattttta ggtgaaacag tggagtctat aataattttt
    12121 gcagttatta ttataaactc tgttctgggt gttgtacaaa caaaaaaagc agaaagttca
    12181 ttagaaagtt tgaaaaattt atctgcacca aacgcaaagg taataagaga caataaaaaa
    12241 atgacaattc cagcaaaaaa tttagtagtt ggagatattg tattcttaga agctggcgat
    12301 tacataccag cagatggaag gcttatagaa gcacaatctc tcaaggttgt agaagggatg
    12361 ttaactggag aatcagaacc agttttaaag catacagaaa aaataagtga agatgtaagt
    12421 ttaggtgacc agaaaaatat ggtatttagt ggtgctgtag ttgtttatgg tagaggttct
    12481 tttgtagtga ctggaacagg tatggatact gagatgggta aaatagctgg gcttttagaa
    12541 agtgctgaaa ataaacttac accattgcaa caaaaaatag aggattttag taaaaaactt
    12601 ggtgtaggta ttgtaatact tgctctttta atatttataa ttcaagtagc aagaaattac
    12661 tttatggctg gaaatggaga aatgacacaa attattttag attcattcat gttctctgta
    12721 gcagtagcag tagcagctat accagaagct ctatcatcaa tagtcactat agtattggct
    12781 gttggaacaa atagtatggc aaaaaaacaa gccataataa gaaaattacc agcagtagaa
    12841 actttaggtt caacaagtgt aatatgtact gataaaacag gtactcttac acaaaataaa
    12901 atgacagtag ttgattatta tatgtatgga actaataatg atgagttaga taaagaaaaa
    12961 gtaaactatt cttatcatgc taaattattg actatggttt ctacattgtg taatgactct
    13021 catataacta gtgatggtaa agaagttggt gacccaacag aagtggcttt aataaattat
    13081 tcaagtaaaa atgatttaga ttatgataaa ttaagaagta agtatatcag aataaatgaa
    13141 ataccatttg actcagacag aaagcttatg tctactgtaa atagtatata tggagattat
    13201 ataatgttta caaaaggtgc tccagatatt gtgtttagta gatgtaaata tgctttgaaa
    13261 aatggttcaa aagtagatat aacagatgag ataatagaag aatataaaca taaaaatgaa
    13321 gagttctcaa atagagcact tagagtatta gcttttgcaa taaaagatgt cccagaagaa
    13381 gattttatac cttcaattga tgacgaacat gacatgacat tggttggaat aatggcaatg
    13441 atagacccac caagagaaga agtaatggat gcagtaaaag aggcaaagag tgctggtata
    13501 aaaactgtta tgataactgg tgaccataaa acaacagcag cagcaattgc aaaagagatt
    13561 ggtataatgg aagaaggaga cttggctctt actggaaaag agcttgatgc tttgagtgaa
    13621 gaacaactat atgaaaaact agaaaatata agtgtatatg ccagagtctc gccagaaaat
    13681 aaaattcgta tagtaaaagc atggcaacat aagaataata taacagcaat gactggtgat
    13741 ggtgttaatg atgcacctgc attaaaacaa gcagatatag gaatcggtat gggaagtggt
    13801 actgatgtag caaaagatgc ttctgctatg gtattggttg atgataactt tgcaagtata
    13861 gtaaatgctg ttgaagttgg tagaacagta tacagtaata taataaaatc aattacttat
    13921 ctatttgcag gaaacttagg agctatagta tccatagtat ttgcagtgtt tgcaggttgg
    13981 tcaaatccat ttacagcttt acaacttttg tttataaact tagtaaatga ctctttacca
    14041 gcaattgcat tagggtttga aaagtcagaa aaaaatataa tgaataaacc tcctagacac
    14101 ccggatgaaa gtatactagc aggaggaaca ttgaaggcag ttgctataag aggttgtata
    14161 ataggtgtag ttacaataat tgcacaatat ataggattac aagtatctcc agaacttgga
    14221 gtagcaatgg cattttcaac attgatatta gctagaataa tgcaaacatt acctgcacgt
    14281 tctaataatc aaacagtaat aaaattaggt tttttcagca ataaatacgt tataggagca
    14341 gttttagtct gtcttgggct ttactcttta acactaatac cagtgctaag aggaatattc
    14401 tctataccaa caacgtttgg attgtaccag ttggggattt gcctagggtt agcattaatt
    14461 tcatcaatat taatggaact taacaaatta ataaatagaa gtgaagtaaa ataatcaaaa
    14521 aattaaaggg catattgatt ttaacaatat gccttttata aatagtctaa tttattctat
    14581 attatcgatt atttggaatg cttttataac ttcaggtaat tctttttctt caggcattct
    14641 aaatcttatg aaatttttat caagtccagt aaaatcactt ccagatataa ctcttatttt
    14701 taatttagca aactcttgtt gtaaatctat gtccttgttt ttatgttcaa ctgtcataat
    14761 tgatacagta tcactagttt cagctatatt aaggtttttc catggaatta ataattgatt
    14821 ttttatatct tttgtttttt cttttaattc ttctataaat tgaacatcat ctaataaatt
    14881 tgctgcaata ctacgagata tttcagacac ttcgtaagga gtagaaatct ttttaatagg
    14941 gctaacaagt tgttctggaa gaactgcata tcctgctctt agtcctgcta aaccaaatcc
    15001 ttttgaaaat gtttttaaag caattacatt atcataatta tttagaagct tgacagctga
    15061 attttctttt ggcatgtatt caccataagc ttcatctacc ataactgcta tatcatattt
    15121 agctgcttcc tttactatat tttcaattga tgataaaggt ataatttgtc ctgtaggatt
    15181 gtttggattg tctatgtaaa ttactttata ttctggattt attttttcaa taaattcttt
    15241 ttcattaaac ttgaaattat cctctttctt taaaagaaca taatcataag ttgcaccatg
    15301 catttttata tctgtctcat attctgagaa ctgaggtgaa tatcctaaaa ctttatctcc
    15361 cttttcaata aatagtctat ttaaaaggta aataacatgt atagaaccat ctgccaaaca
    15421 aattctgtca gtatctaatg ctataaaatc tttccaataa tcgactatat tatcttttaa
    15481 agcaattgaa tgaggatatc ctcttatcat atcaaatttt aaagcattaa aagcttctac
    15541 agctttgttt gagtaagaca cggtatttat accttcacca cagtctatct cgaatacatc
    15601 ttctgaatgt ccagattcta ttgcataact ttttttcaac tgcatttcaa tagctttgtt
    15661 aatttttagt ttcatacttt atcactcctt atttagtcaa taataaatgt tataaaagtt
    15721 gctagattta aaatattatg aaaatatata atagtaaaaa tgaatataaa tattataata
    15781 gctcacttta tttaatatga ttatatatca tatattgtaa aatttctagc attataagac
    15841 tataaattga aaatattcag aaaaatacta caagaaacga tttattttgc tcttaaaata
    15901 agttaaatga atgttattaa ttttgtaaat tgaaatagtt taagtataaa gttatgatat
    15961 aatctaataa gggtaattct ttagattata ttaaggaaat ataggtatac aataaaaagt
    16021 tatggagttg gattatggga tataaattaa ttgtaacaga tatggatgga actttattag
    16081 gcaataatca taaagttaca gatgaaaata aaactgcact acaaaaagtt ataaaaagcg
    16141 gtattaatgt aactttagca acaggaagag ccttcgattc agctaaatgc aatgtagatt
    16201 ttcttaaaga ggacatgcca ataatagctt gtaatggttc attaataaga gagcaaaatg
    16261 gaaatataat atattcaaat aagattgata caagaacatg tttaaacatt ttagatgtat
    16321 tagataaata cgatatttac taccaatgta atagtataga ttctatgctt tcgaaaaaaa
    16381 tagaaggacg tgaagataga ttaagtgtat ttttaggctc tgaaacagaa gtaattgtaa
    16441 aagatgattt gagagaagaa atctttaaaa aagatatact aaaatttgta atcatagaag
    16501 aaaaaaatcc atctattttg gatgaaataa gaaaagaatt gagaaaagtt caaggaataa
    16561 agataacttc ttcatggcca aacaatattg aagtcatgaa tgaaggtgtt gataaaggta
    16621 atgcagttaa aattttagct gaaaaaatga atatagacag agaagatata attgcatttg
    16681 gagacaatta caatgacata gaaatgataa agtttgctgg tcttggggta gctatgggaa
    16741 atgcagaaga attgattaaa caagaagctg attatgttac agatacaaat caagacagtg
    16801 gagttgcaaa ggcaatttat aaattcctag agttaaaaga atcacttagc tcttaaaaca
    16861 gtatataata ggaaaaaata ggttgactat tttgtagata gtaattataa tacaaataga
    16921 taaaacataa aaatttagat tcagtgaaaa agagagtaga tatagagaaa atctcagcga
    16981 attgggggat ggtgtgagcc taatgataac actttatatt gaaaagaact ttggagaata
    17041 ctacttgaaa ttcagtatgg tagtaggtaa tctcgcctta agagaataga gtgggtaaac
    17101 attgtttacc aactagagtg gtaacacgga atatttcgtc tcttggtctt tttgaccaag
    17161 agatttttta gtttcattga gttacaagac ttataattaa aatacaaaaa attaaaatat
    17221 gaggtgaaag ttatgaaatt atggggcgga cgctttagaa aagcggaaaa tcaacttatg
    17281 gaagaattta ataaatcttt tggctatgat tgtgtactgt acaaaaaaga tatcgaagga
    17341 agtgtagcac atgttcatat gcaagtaaaa tgtggacttt taacagaaga agaaggaaag
    17401 tctataacag aaggtttaaa agggatactt gaagatgtag aaaatggaaa gttagtattg
    17461 gatggagagt atgaagatat acatagtttt actgagataa atttaattca aagaattgga
    17521 gatgttggca agaagcttca tacagcacgt agtagaaatg accaagttgc agttgatatg
    17581 agattgtatg ctaaagaaaa agcaaatgat ttggtggatt taatatctga atttaaagct
    17641 actataaaag atgttgctga caaaaaccca gtgatgatgc caggctatac tcatcttcaa
    17701 agggcacaag tagtgacatt taagcatcac ttaatggcat attatagtat gtttgataga
    17761 gatgagaaaa gaataaaaaa tgctatagaa atattagatg aatcaccttt aggctgtgga
    17821 gctttagcag gaactacgca tgatatagat agaagtataa cttgtgaaca attaggattt
    17881 aaaaaagtag tagataattt tatggatgga gtaagtgata gagattattt actagagcta
    17941 atgagtgatt tttcaattat aatgatgcac ttaagtagat taagtgaaga gttgatactt
    18001 tggagttctc aagaatttgg atttgttgag atagatgatt tatatacaac tggaagtagt
    18061 ataatgcctc agaagaaaaa tccagatggt gcagagctta taagaggtaa gactggtaga
    18121 gtatatggaa acttatttgg tctttttaca gtaatgaaag gaataccatt agcatataat
    18181 aaagacatgc aagaagataa agaaggtttt ttcgatagtg tacatactct tgaaatgtgt
    18241 atacaaataa tggatagaat gatagccaca ctaaaggtaa atgaggataa aatgaaacaa
    18301 gcagtaaaaa atggtttttt aaatgcaaca gaagttgcgg attatttggt taaaaataat
    18361 gttgctttta gagatgcaca tggtatagta ggaagtatcg ttatatattg tgaagataat
    18421 aaaaaagcaa tagaagattt aacattagaa gaattacata agttttcaga tgcttttaag
    18481 gaagatattt atgatttta
//
LOCUS       DAEOTL010000082        18286 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEOTL010000082 DAEOTL010000000
VERSION     DAEOTL010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.082"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            136..2007
                     /locus_tag="KRH82_003104"
     CDS             136..2007
                     /locus_tag="KRH82_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBG8656369.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            complement(2099..3034)
                     /locus_tag="KRH82_003105"
     CDS             complement(2099..3034)
                     /locus_tag="KRH82_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBG8656370.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            3554..4066
                     /locus_tag="KRH82_003106"
     CDS             3554..4066
                     /locus_tag="KRH82_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBG8656371.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            complement(4221..5282)
                     /locus_tag="KRH82_003107"
     CDS             complement(4221..5282)
                     /locus_tag="KRH82_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBG8656372.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(5406..6299)
                     /locus_tag="KRH82_003108"
     CDS             complement(5406..6299)
                     /locus_tag="KRH82_003108"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBG8656373.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            complement(6309..7790)
                     /locus_tag="KRH82_003109"
     CDS             complement(6309..7790)
                     /locus_tag="KRH82_003109"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBG8656374.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     misc_binding    complement(7898..8129)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8931..9839
                     /gene="trxB"
                     /locus_tag="KRH82_003110"
     CDS             8931..9839
                     /gene="trxB"
                     /locus_tag="KRH82_003110"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBG8656375.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     gene            complement(9929..11752)
                     /gene="typA"
                     /locus_tag="KRH82_003111"
     CDS             complement(9929..11752)
                     /gene="typA"
                     /locus_tag="KRH82_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBG8656376.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            11964..12206
                     /locus_tag="KRH82_003112"
     CDS             11964..12206
                     /locus_tag="KRH82_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656377.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            12354..12545
                     /locus_tag="KRH82_003113"
     CDS             12354..12545
                     /locus_tag="KRH82_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBG8656378.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            12829..15330
                     /locus_tag="KRH82_003114"
     CDS             12829..15330
                     /locus_tag="KRH82_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBG8656379.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAEAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            15490..16158
                     /locus_tag="KRH82_003115"
     CDS             15490..16158
                     /locus_tag="KRH82_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656380.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            16142..17419
                     /locus_tag="KRH82_003116"
     CDS             16142..17419
                     /locus_tag="KRH82_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBG8656381.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            17820..18041
                     /locus_tag="KRH82_003117"
     CDS             17820..18041
                     /locus_tag="KRH82_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656382.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EIKKDEMMERYEQKKFSKELEKQMKNEMK"
BASE COUNT         7013 a         2234 c         2844 g         6195 t
ORIGIN      
        1 attataaaat ttaaaattta atgttacaat atagtgacaa aaggtaaaaa ttcaatatta
       61 tagcattaat tgtagattat aatgtataat aatgtttgag agaatatatt ttataaaatg
      121 ggtaggtagc gaataatgaa aaatacaaaa ttttctataa aaaaaataaa aaatatatct
      181 aatgacccga aagtcgtaca tactaagggt gccctccttg aaaagatggg taagatggaa
      241 agcgcaatag agttgtataa gagtgctgca ttggataatt acgtaaaatc tcaatatact
      301 ttaggaaata tatatgaaag taaaaaacaa tttaaagaag cagaaaagtg gtattcaatg
      361 gcatataaaa gtggaagtga agatgctgct tttgatttag gtaatatgta ctataagtta
      421 gatggctatg aatatgctat atattggtat gaaaagatag caaatttagg ttatttacaa
      481 gcacaaaata atttaggtgt atgccatttt aaaatgaaag attttgtaag gtgtgaaaaa
      541 tggttaaaaa cagcagcaga caagaattta ggtaaagctt gttttaattt aggggtatta
      601 tatacttttt tggagaaaga tgatgaagcg tatgaatact ataaaaaagg ttctgtgctt
      661 ttagatgatg atgcaaaata taatttagca atattaaatg gaaaaaagaa agataataaa
      721 tcaacagtaa gtttatataa acagttgtac aagtcaggtc atatgaaagg ttgctttaac
      781 ttgggtatga ttatggaaat aaatgataat ttagaagatg cagagaagta ttataaaaag
      841 agtgctgata gagatgatgt gaagtctgag tataggcttg catatgtata tgatagaaaa
      901 gaagagctgg gagatgcaat ttattattat gagaaagcaa tagaaaaaaa tcatacactt
      961 tctaagtata gacttgctaa tttatataat agagaaaatg agatagagaa ggcaaaaact
     1021 tattataaaa tggctgctga agatgatata acagaggcaa aaaataatct ggcaggtata
     1081 tattttgaag aaaaagatta tgaaaatgct attaaatatt atgaggatgc tatagctgtt
     1141 ggatgcaaaa gttcccttga aaatctaggg gatttatatt atcagaatca agatatagaa
     1201 aaagcgattt cgtattattc gaggattcca aataatgtat cttgtcaaat caaattagga
     1261 aatatctatg aagatttaaa taatattgaa gaagccataa gttggtataa gaaagcatct
     1321 gaaaatggag atacgaggtc tagttataga ttggggtgta tatatgagag cttaggaaat
     1381 acaaaaaatg ctagaaagta ttttgaaatg gcaagtagca aaaaccatat gaatgctcgt
     1441 atacatctag gtagaattta ttttagagaa ggtaaattgg aagagtctaa aatgatgttt
     1501 gatacacctg ccaatgaaaa taatgtgtat gctcaacata tggtaggatt aatttatgat
     1561 atgttctata aagattatgt aaattctaaa ttttggtatg aaaaggctag agcacaaggt
     1621 tgtgttgaat caatatataa tttaggtcaa atttatttaa aattaaatga tgacgcagaa
     1681 gctgagaaat attataaaga aggtattaaa tatggaagta agaagtgtga gtatatgctt
     1741 gcaggtcttt attataaaaa gagcctagat atgtacgttt ctttagcaaa tgaagagtac
     1801 gataattgtg aagagatagt agaaggcttt cctaatttaa atatagactt tgatgaagta
     1861 ttaattcctc catttaagtt gcaagaagag gtaatagatg aagaagagta tgtaccaatt
     1921 tatatactaa atataaaaga aagtttagat tcaatgctag aagggcttga aactgaaatg
     1981 attatagatg aagaacatga tagttaaaaa gtattatagg attatataga tttaaatata
     2041 taaaagccat taggataaat gtaaatcaat taattctaat ggctttttta ttaatatttt
     2101 ataatagctt atttcttgac atgaaaaatg taatcactat acatattata gaggtaataa
     2161 gaagtattat ccaaaatccg tttgggttat tagaaaatgg catgttgatg acattcatac
     2221 caaagaatcc tgatattatt gtaggtattg agaaaattag tgtaactact gttaaaattt
     2281 gcataacatt attctgatta ttacttataa ttgcactgaa agcatccata attctactca
     2341 atatatctcc atatatttta gccatatcaa gagcctgtct attttcaact ataacatctt
     2401 ctaataggtc ttcatcatct ggatacttct ttataccagc agttctaacc attttgttta
     2461 aaacaagttc attagatttt agtgaggtag agaagtatac caaagatttt tctaattcca
     2521 ataattgaac caattctttg tttttcattg atttgtaaat ttctcgctct attatgattg
     2581 tcattttatt tatttttctt aagtaatgca agtaataagc tgcatttttg tgaagaattt
     2641 gaagcaaaaa gcgagtcttt ttaaacgtaa aaaaatcttt aatatgacca actataaagt
     2701 catttaaaat cttagtttgt gcatcacaaa ctgttacaat agcttcttca gttagtataa
     2761 tacctaaggg tattgtagta taatgagaag aattagagtc actttcgtct actggtatat
     2821 ctataagtat aagagtatga ttgtcttcaa catctattct tgagcgttct tcttcatcta
     2881 gtgcagattc tatgctttct acatctatat ttaataaatt agaaatttcg ttgatttcac
     2941 tatgattagg ttcaacaaga tttatccaac agccatcttc aaaaaaacta agtttctcta
     3001 attttgaatc tatagttttg taatatctta tcatggcaac acatccttta ttcagtttta
     3061 tataaatctc atcatttaat agtatctatt aattaactaa tttatataac tgaatatatg
     3121 tattagtttt gattttagat attattaagt gatgaaaatg taaaaaattc tctccgcaac
     3181 ggactagtat ccattgccca tcactctcct tatttattat tttatatata gctatttatg
     3241 aaatgcgtat tttaagcact ctttaatata ataccttttc caggtatata aatcaagttt
     3301 tgatttgatt aaataatatt tttaccacaa tttacacata aagtatataa gttatattta
     3361 atttgagtaa agaatatata tattctgagt gaaattatta aatatattaa aaaataagag
     3421 tgtatatata tatttactta tttgcaataa tatatttaaa aaagtatttt attttcaaaa
     3481 ctagacttca tttataattt atcacgaaaa taaaaggaat ataaatataa gagaatgaga
     3541 ggttattaga gatatgagtg attttaaaga aattttggca gaagagatta aaaataatcc
     3601 atttggattg ataggtaaag attggacact tataacagca gaaaatgaag gtaaagtgaa
     3661 tacaatgact gctagctggg gagggcttgg agttatgtgg ggaaaagatg ttgcttttgt
     3721 agtaataaga ccacagcgtt atactaagga atttatagat aatacagata aattttctct
     3781 tacatttttt gatgaagatt ttcgtaaaga gctttcatat tgtggaaaag tatctggtag
     3841 agaagaggat aagatatcac agattggatt taatatagaa cacttaaatg atacacctta
     3901 ttttaaagaa tctaaaatgg ctattatatg caaaaaaatg tatagtcaga aacttgaacc
     3961 tcaatgtttt attgctgaag gtatagatgg aagatggtat ccacaaaaag attatcatac
     4021 tttatatata gctgaaataa ccaatgtact tgtaaaagaa gattagttat aaaggttaat
     4081 actatttcta attaaattaa aatttccata aaagtaaatt gacacaaaaa agctaaggac
     4141 ataaatatgt ttataaagat taataaataa cgtatttaaa ctccttagct tgataaaatc
     4201 ttaatttagt tttctttaaa ttataattca gaaatcaatt cattgataac atcttcaaca
     4261 gtacttaatt tatcaatttt ataggcatca tttccacaaa ataaaagtga attttcaaca
     4321 tctcctttaa ctgcattgat tagagcttga gaaatacagt aaggagtttc ttttggatta
     4381 caaggaatca aacaattata gcacttcttt atttctggac gatttatttt aacttcttct
     4441 ataaatttgt ttcttatggc gcgtccagga agacctacag gacttttaac tatatgaaca
     4501 tcttcttcac tagcatttat gtatgccatt ttaaagttct catgggcatc acattcgtaa
     4561 gtagcaacaa atcttgtacc aacttgtaca ccacttgcac ccatatctat atatttttta
     4621 acatcactac tagaagttat accaccagca gcaactactg gtatgtttct accaaatttt
     4681 tctccataag tatttgcaac ctttaaaatt tcaacaaatt ccttatcata gtctatagaa
     4741 tctatgttat caagttcctc gttagagtat ccaaggtgac caccagcttt tggaccttca
     4801 acaactatta agtcagcagt agttttctct tttctatccc acatttttaa aattacatta
     4861 gcagcttttg cagttgaaac tatgggtgct atttttacat tacttccctt tactaatgat
     4921 ggtagcttat taggtaatcc agctccagat attataaggt ctacaccagc tttaacagct
     4981 tcctttacgt atgtttcata ttctttcata gctaccataa aattaatacc aataatacca
     5041 ccatttgaga tttctttggc cttagaaata tgttttttta tagctcttaa atttgcattt
     5101 atagtattag tttcaaaatc ttcctcatca tatccaattt gaactccaga aattacacca
     5161 acaccaccaa gcttagcaac tgcaccagct agtgatgacc tagatatacc aacgcccatt
     5221 ccaccttgaa ttataggaac ttttgcaact aaatctctaa ttattaactc ttttatgata
     5281 atccctcctc aatgtaaaca tgtttaaaga actagattat aatacttaat attattacct
     5341 agtcctaatt attatactac aaattataat aaaagagtag ttatattttg tatagaagac
     5401 gataattata ttatatttaa aacagctcca ttagaatcgc aacataactc ttttatttcc
     5461 caatcagatt ttagtttttg taggtaattt ttcatattat ccacaaaact atcatcattt
     5521 tcttttatta aagacattat agtaggtcca gctccactta aaaatactcc aatactattt
     5581 aattgttcag atttttcaac aatatcattg tagttctcaa ttagagttcc tctataatct
     5641 tgatgcaatt tgtcttgaca agctacttta agtaggtcaa agtttttgtt tagtaaggca
     5701 gatattagta aagcaactct actaacattg aataccccat cagaatatgg tatttccttt
     5761 ggtaaaacac ctctagcttt ttctgttgat aacttaaaat taggtatcat tgcacaaaat
     5821 ttaagttctt caggaatttt tataatatca taatgtatgt tctcattatc agtaacagat
     5881 acaatcatat ttcctaaaat agcaggagca acattatctg ggtgaccttc tatttctgaa
     5941 gctatattta gtaattgatt tttatctaaa ttagcacctg atagagcatt tgcagctata
     6001 actccagcta ctatacaaga ggcactactg ccaagacctc tacatatagg tacttcactt
     6061 tggattttta ttttgatacc agcaggtatt ttttctggtt taactctatc aaaaaagtac
     6121 ttcatagatg tataaactaa gttgttttcg tttttgtaag catcttcaca accttctatt
     6181 tcaagaccac tttcaatttc ttcaacataa aatttattgt atatatttaa cgcaattcca
     6241 agacaatcaa atcctggacc tatattagca cttgttgcag gaactataat ctctaacata
     6301 ataatcacct atacctttaa gaattttttt atagctagtt ttaattcatc tttttcataa
     6361 atatctttat gtagtatttc tgcattttta agatttttaa taggttttgg aatatctatt
     6421 ttagaaatac ttgataatct atcaattata gcaaagtcat caaggtcttt aaaatcacaa
     6481 tctatagact ttagaacatc ttcagaaaac ttgaatggac ttgcagtact tacaataaca
     6541 gtttttgtgt tatcagaagt ttctttttta tatttttcat aacaattgta tgcaacagca
     6601 gtatgagtat ctatcaaata attataattt ttaaacacat tgtttatcgt gcttttaact
     6661 tcttcttcat ttgaatattc tccatagaat gaggctaaat ttttttccat atcatcactt
     6721 attttgtaga ctcctttatc actaaggtct gataaaagct tatttacaat atcagtattt
     6781 ctatttgata tttcaaacag taatcgttct aaattacttg aaattaatat atccatagaa
     6841 ggagaagtag ttaatttcaa tgttctattt ttatcatata caccagtttt aaagaaatca
     6901 taaagaacat tattatcatt tgatgcacat atcaatttgt ttattggaag acccatttgt
     6961 ttggcataat atccagctag aatattacca aaattaccag ttgggacaac aaaatttatt
     7021 ttatcattta aatttatctc actattgcta actaatttca tatatgaata aaaatagtat
     7081 gcaacttgtg gaagaagtct tcctatatta attgaatttg cagaagataa tatataatta
     7141 ttatccaata gtttttgatt aaattcttta tcagaaaaaa tcttctttac acctgattgt
     7201 gcatcatcaa aatttccttt tataccaact acatatgtat tttttccagt ttgagttttc
     7261 atttgaagtt tttgtactgg gcttacacca tcttctggga agaatacaat tatctttatt
     7321 ttatctatat ctttaaatcc ctcaagtgca gctttacctg tatctccaga tgtagcagta
     7381 agaatcacaa catctttctc taaattatct ttctttatag atgttttaag aagatgaggc
     7441 attatagtaa gtgccatatc tttaaatgct aaagttggac cgtgatatag ttctaagaaa
     7501 taagtatcat ttactttatt taatggagct atactactac aatcaaactt ttcatcatat
     7561 gcattttcta tacaattttt aatttcatct tcagtaaaat cacataaaaa tttactaagt
     7621 acaaaaaatg ctatctgaga atacgttaaa tttactaaat ttataagttc attttttaca
     7681 ttgggaaatt cacttggaac ataaagacca ccatcacttg atattccttt tattattgct
     7741 tgtgatgcag ttactttttc ttcggtgcct ctcgtacttg aataatacat tttttataat
     7801 cctccatata ttttaaattt ttaattagct aattaaatta gatacagaat attttaaaaa
     7861 ctgaatttag gtaataaaaa aagaccctca tccctaaaaa agggacgaga atctgtttcc
     7921 cgcggttcca cccaaattga ttttaaaaaa tccacttgat actttaacgc aagtaataaa
     7981 aacgtctatt cctactaaaa tcattaagat aacttcggat agaagctcct aggtagtttt
     8041 caatccttct aattagggaa acatttcagc tagtagtttc cttctctggt aatcgattca
     8101 gatttactct tcctaatcaa tgcctttcaa tattcttaat attattaatt attctagttt
     8161 ataaaacaga caaagtcaag tattaatata aaaatttgga aaaaatattt tttaaattgt
     8221 aaaaaaattg taatcaaatt gagtattaga aaaatatttt tttaactttt ttaaaagttt
     8281 aaaaacctag attttcatag tgatgaagct gtttttaatg aaagtaatta aaagataact
     8341 attaaatatc tgtaatatta caattttata ctacactata ttacaaaaaa agtttacaaa
     8401 actttaattt gaaaaatgta attatatggt atatcatata aatataagta aatagtgcta
     8461 atatttaaac tattaatcat aattggttca acaaaagtat atagttaata atgtttaatt
     8521 tgaagaaatt gttagtgtga aattacatat atattcaaat taaattcata aatatttcac
     8581 ataataatag tatactgtaa acaaaaggag gtattaaata tgggaatagt acttataaca
     8641 gcagcattag ttttggttat gtatggactt tcaattctat catatatatc agaaagcaat
     8701 atattagaag acactgtaaa tgataaccaa taaggttttg aattatataa ataagtgaga
     8761 actgtaaata aaagttaatt tttatttgca gtttttttat atatatgtaa aataaagtta
     8821 attaataaaa aataatgttt tgtttatagt atatatggat aataatagta aagtataaga
     8881 atgatgagaa taatatataa gaaataataa tataaagaga ggtaaacgtt atggtagata
     8941 tcattgtaat tggtgctgga ccagcaggtt taacttcagc aatttatgct atgagagcag
     9001 ggttaagcgt tacagtattt gaaaaaaata tttatggagg tcaagttgca agtacctctg
     9061 aggtagaaaa ttatccagca gttcaaaaga tttctggggt agaattttct aataatatat
     9121 acaatcaagc agttgctcaa ggtgttgata ttcagtttga tgaggttgaa gagataaatt
     9181 tagagggaaa agtaaaggtt gtaaaaactt cttcaggtga acataaagca aaggctgtta
     9241 ttcttgcaaa tggagttgaa agacgtaaat taggttgtgc aggggaacaa gaatttacag
     9301 gtagaggagt atcttactgt gcaacatgtg atggagcctt ttttaaagat aaagaagttg
     9361 ctatagtagg tggaggaaat actgcactag aagatgcttt atttttagct aataattgta
     9421 caaaagtgta tttaattcac agaagagata gttttagagg tgaagaagtg ttggagaaat
     9481 ctgtgaaagc aagagagaat attgagatac tttacagtca tggtgtagaa aaaatagaag
     9541 gagaaaagac tgtatcgaaa atagaagtaa aaaacttaaa gactgaagaa aaaagaacta
     9601 tagatgttag tggtattttt attgctatag gtcttaaacc taataataaa atgtttgaaa
     9661 atgttcttga tttggatgaa ggtggatata taatttcaga tgagtcttgt acaacatcag
     9721 tagaaggtgt atatgtagca ggagatagta gaactaagtt tttacgtcaa ataataacag
     9781 cagcatcaga tggagctatt gcagccgttc aagcagctaa ttatataaat gttgaataat
     9841 ataaatttca aataaaaata gccatataaa ctgaaataat ttttcagtac tatatggcta
     9901 ttttgttaat tagaggtaaa tgtacgtttt atttaccttg tctagatttg ttatatctta
     9961 atctatcatg ttcatttaag aatctttttc taagtcttat agaatcaggt gtaatttcaa
    10021 ctaattcatc atcttctata aactctagtg cttcttcaag agtaaatatt ctaggaggag
    10081 ataattttat agcatcatct gaaccagaag cacgtacgtt actcattttc ttgtttttac
    10141 aagggttgac taccatatca tcttttctgg aattcatacc aattatcata ccttcgtaaa
    10201 cttctacacc agggtctaca aacattacag ctctatcact taaggcatta agagaatacc
    10261 ccatagtaac accaggtcct tgtgctatta aaacaccatt tcctcttgaa ggtatttctc
    10321 ctttaaattc ttcaaatttt tcaaatgaac gaactaaagt accttctcca cgagtagcgt
    10381 ttataaattc acttcgatat cctaaaagac cacgagtagg tgctaagaac tctattttta
    10441 catagtctcc ttctattgac atagactcca tcataccttt tctcatgttt aattcattta
    10501 taatagtacc agagtaaact tcaggacagt ttacaacaac tctttctatt ggttccatta
    10561 gttttccatc ttctttatgc attaaaactt caggtttaga aacaccaact tcataacctt
    10621 cacgtctcat attttcaagt agtatagata agtgaagctc tccacgtcca gaaactttgt
    10681 atccatcagt agtatcaaga ggttcaactt taagaccaac atttacttca agttcctttt
    10741 caagtctatc tttcaaatgt ctagttgtaa cgaattttcc actttttcca acgaatggag
    10801 agtcgtttac taagaagttc atagaaagag taggctcttc tatttttatc atttccatag
    10861 gtagtggact atctaaatcg catatagttt cacctataga tatatcagga ataccagcta
    10921 taacaactat ttctccacta gtagcttcat caacttcaac ttgttttaaa ccttcataca
    10981 cagaaagttt tgatactttt cctttagata caacagaatc ttctctacat atagcaactt
    11041 gtgtattgtt tttaagagta cctttgtaaa ttctacctat accaagtcta cctacataat
    11101 catcatatgc aagagctgat atttggaact gtagaggttc attatcgtaa ttaggataag
    11161 cttcaacgtg atttacaata gttttaaata gaggagaaag gtcttcacta tcatcatcca
    11221 tttcaagttt agcaatacct tgtttagcaa taccatatat tataggaaat tcgcattgct
    11281 catctgttgc atttaagtct acaaataaat cgaaaacttc attaactact tcttccgctc
    11341 tctggtcttt tttatcaatc ttgtttataa ataatattgg ttttaaaccg aactctaaag
    11401 atttttgtaa aacgaatcta gtttgaggca ttgggccttc actagcatca actaatagaa
    11461 taactgtgtc aacagttttc ataacacgtt caacttcaga agaaaagtca ctgtgtcctg
    11521 gagtatcaac tatgtttatt ttgtaatctt catagtttat tgcacagttt tttgaatata
    11581 tagttatgcc tctttctttt tcaaggtcgt tactgtccat aacgcagtct ttaactactt
    11641 cgttctttct aaaaacaccg ctttgagaaa ggaaagcatc aaccaatgtt gattttccag
    11701 cgtcaacgtg ggctataact gcgatattta taattttatg tttttgtgac atttttgttg
    11761 ctcccttcga ttaaaataac ttattaatta tagcacaata tattattagg tacaaggagg
    11821 aatatattaa attgtattaa tatagtttaa attggataaa actgttagtt ttgcatctga
    11881 aaattattct gtttaaaaaa attttttaga caaataataa ccttaataga taaaaagatt
    11941 aataaaagag taaaggatga tatatgttgg aagtaaccaa aataataatt aaatattttg
    12001 caagtgaaag tgatactttt gtaaaagaag aagtttgtaa ttttgaagaa cttcttaagt
    12061 ggtctcataa atttattgaa ggtaaaaaga tagaagatgt tttgtatata aagtctaaag
    12121 aaaactataa agtaaatgtg attaagtctt tagaaattaa ggaattggaa atagtgagaa
    12181 aacaacagat accaccgtac atgtagtatt aataatatat aaaattaata tgtaatactc
    12241 gcaataggat ataaatggta tatatggtaa taatttatat taaaaaaact tttataaagt
    12301 ttatatttgg gtataaaagt attaattaga cattaattag gaggaactta aatatgataa
    12361 gagtatgtcc aaactgttca aatgtggatg taaataagct aaaaactttg gttggagaag
    12421 aaaatgtaaa gactggttgt ataggtcagt gtagagcatt taaaaaagaa gctgttggaa
    12481 taatagacaa tgagcttgaa ataaaggaaa cagaagcaga gttttttgaa gcatgtaaag
    12541 aataaatttt aaataaaata taataaatag agcatctaaa ttgtataagt attaaacaat
    12601 ttagatgctc tatttttata tatacattta attatgagta tacttttcta ttaaatacaa
    12661 ataaatataa ctaatacatt tatttattaa aaaaatattg atttaatata cctatagggg
    12721 gtataataaa aatatagatt tctaaataag taatttatca atattacata tcaaaataaa
    12781 acgttacaaa ttagctgaaa atatattgaa agaaaggaag attttattat gagttcaaat
    12841 aaagtggtag aaagttataa aattacaggt atgacatgtg cagcttgtgc aaaggcagta
    12901 gagagagtaa ctaagaagat ggatggagta tatgaccaaa gtgtaaatat agctactgaa
    12961 aaacttaaaa tagaatatga taattctaag gttaattttg atgatataaa gcaggttgta
    13021 gaaaaagcag gatatggaat tataaaggaa gaaagtaata aaaaaattga tatgaaaatt
    13081 gatggaatga catgtgcagc ttgtgcaaaa gctgtagaga gagtggtaaa aaaattggat
    13141 ggagtagaaa gtattagtgt gaatattgca acagataaag ctaatataga ctatgaccca
    13201 tcaaaagtaa aattatctca aataaaagca gctattgaaa aagctggata taaaccaata
    13261 gaagaggtaa gaaataaggt tgatgtggat gaagataaat tgagaaaaga aagagaaatg
    13321 aagtctttat ttgttaaatt tatagttgca atagtatttg cagtacctct gttttatata
    13381 gcaatgggac ctatgataat aaagcctata gggccatggc ctttgccaga aattataaat
    13441 cctatgacaa atacttttaa ttatgcatta attcagttaa ttttagtaat accagtaatg
    13501 atagctggtt ataaatttta tataaatggg tttaaatcac ttttttcttt aagccctaat
    13561 atggattctt tagttgcaat aggaacatta gccgcatttt tatatagtct atatacgaca
    13621 ctacaaatag ccaatggaca aattcaaggt atgcaccatc atcagttgta ttatgaaagt
    13681 gcaggaataa taatagcact tatcttactt ggtaaatatt tagaatcaaa atcaaaagga
    13741 aaaacatcag aagcaattaa aaagcttatg gggctacaac ctaaaactgc aatagtgtta
    13801 gttgatggta aagaagttga aactcctata gaagaagtag agataggaga tatactatta
    13861 gtaaaaccag gaactaaaat acccgtggat ggagttgtaa tagaaggata tacatcagtt
    13921 gatgaatcaa tgcttacagg tgaaagtata ccagtagaaa agaatgttgg aagtaaggtg
    13981 acaggagcta gtattaataa aaatggtgtt attaagttta aggctgaaaa aattggtgga
    14041 gatactgctc ttgcccaaat aataaagtta gttgaagatg cacaaggtac aaaagcacct
    14101 attgctaaac ttgccgatac tgtatctgga tattttgtac caatagtaat tgcaatagct
    14161 gtagttgcat cattattgtg gtttttaata ggaggaaaag atatagtatt tgtacttact
    14221 atatttatat cagtacttgt aattgcttgt ccttgtgcat taggattagc aacaccaact
    14281 gctataatgg ttgggactgg aaagggcgca gaaaatggaa tcttgataaa aggtggagag
    14341 gcactagaat ctgcacataa agtaaataca gtgatatttg ataaaacagg tactataaca
    14401 gaaggaaagc caaaagtaac agatatagta ttaaataata atgtaaaaga agaatatctt
    14461 atcaagattg cttcaagtgc agaaaaaggt tcagagcatc ctcttggaga agcaatagtt
    14521 aagtatggag aagagaagaa tataaaattt gaaaaagttg ataattttaa agccatacca
    14581 ggtgctggta tacaagttac tattaatgat gaaagtatat tacttggaaa tagaaagctt
    14641 atgaatgaca ataatataaa gcttggggat ttagaagaaa aatcaaatat attggcaagc
    14701 caaggtaaaa cacctatgta tatagctgta gatggaaatt tatcaggtat aatagcagtt
    14761 gcagatgtag tcaaagaaag tagtaaaaaa gcaatagaaa tacttcatga tatgggaata
    14821 aaagttgcaa tggtaactgg agataatgcg aaaactgcaa atgctatagc aaatcaagta
    14881 ggtatagata tggttttggc agaggtttta ccagaagata agtcaaaaga agttgaaaaa
    14941 ctacaaaatc aaggaaagtt tgttgcaatg gtaggggatg gaataaatga tgccccagct
    15001 cttgcaaaag cagatatagg gatagcaata ggaagtggaa cggatgtagc cattgaatct
    15061 gcggatatag tacttatgaa gagtgattta attgatgttc caacagcaat taaacttagt
    15121 catgaaacta taaaaaatat aaaacaaaac ctattttggg catttggata taatacaatt
    15181 ggtatacctg tagcagcagg aatattatat gtatttggag gacctttatt aaacccaatg
    15241 attgcagcag aagcaatgag cttaagttca gtttcagtcg tatcaaatgc acttagactt
    15301 aaaaacttca aggcatataa gagagattag attaataaat taaataaaat gtatccaaaa
    15361 gagctatctt taaattaaaa ggattaattt acaaattaag atagctcttt tttcatgtaa
    15421 aattcacaac aataagataa aatataagta atatacgaaa ttttaaataa aatagaaagg
    15481 attgatagaa tgaattcgtc aatacttgta attgaagatg attcaaatat acaagagtta
    15541 atatcagaat ttttaagtgc agaaggttat caagttgata cagcaaatga tgggttggaa
    15601 ggtatacaaa agtttaagca aggaagttat gatttagtca tattagatat aatgatgcca
    15661 aacttagatg gttatggagt ttgtaaaatg ataagaaagt catcgagcgt tccaattata
    15721 tttttaactg ctttaaatga tgaaggagac caacttaaag ggtttgactt agaatgtgat
    15781 gattatataa caaaaccatt ttcatttaat cttcttataa aaagagtaga agcaatttta
    15841 aggcgaagta acaagactat aaatgacaaa tttatagttt ttgaaaaatt aaaattagat
    15901 ttaaacacat atattgcaga gatagatgga gaacctatag aacttacact aaaagagttt
    15961 aatatattaa aagctttgat agaaaagtat ccacaagtta taactaggga aggtcttttg
    16021 gatagtatat ggggttatga ctattatgga gatactagga ttgttgatgc acatataaaa
    16081 aatataagaa aaaaaatatc attaccatat attaaaactg taaaaggaat aggatataca
    16141 cttgagaagg atatttgata agtgggaaaa gttaagtata aagtataagt tattttcaat
    16201 aacgacatca ttattaatag cattagcttt aataatatat ctaattttat attttttatt
    16261 gccatcatat tatcatgagt ataaaattga gtctcttcaa gaaagtttga aatctttagt
    16321 agatagttca attcatttcg atacatatac tttagaagaa agactttatt atatggctaa
    16381 agaccaaaat ttggctattt tattaaaaga taaccaaggt aaaattgtat atggtaagaa
    16441 tgaagtagtt attttaagat atagtaagta catgattaat agtcttgagg atgagtatag
    16501 aacttctata cctatatata ctaaagatgc aaaagatggt ccatatactt tagaactcgt
    16561 tatgccatta caaccaattg acgaagcaaa cgaagttata agaaaactaa tgccatacat
    16621 catatcaata gcaatattga tagcgattat tggagcatat atatattcaa ttgtaataac
    16681 aaagcctctt ataaacataa tagagagtga gagagaacag gaatatagaa ggaaggattt
    16741 tgttgctaca atatcacatg aactaaaaac tccaataacc ataataagtg gtcaaattga
    16801 aggtatgatt tatagtgtag gtaagtataa ggatagggat acttatctga aaaaatcgta
    16861 tgagtgtaca caagaattaa aagatttagt aaatgaaatg atagaggttt caaaatcaga
    16921 aatacttgaa aaagatttga aattggtatc aataaatata agtgaattat taaatagact
    16981 tgtaaagaga caagtatttt taatagaaga aaaacatatg aaaactattt taaaaataga
    17041 agaaaatttg gaaattaagg cagaccaaga gagaataact aaggcaatca ataatataat
    17101 aaataatgcc ataaaatatt ctcctgaaga atcagagctt ataattagac tctatgataa
    17161 aaataaacga ataagtaaaa agacttctaa tcaaagagtg gttttagaaa ttgaaaatac
    17221 tggtgtaact atcgagaaac gttatttaga agaaatattt aatccatttt atagaataga
    17281 aaaatctcgt tcaagaaaaa ctggaggaag tggacttgga ctttatatag tcagccaaat
    17341 ttttaaaagt catgggtttg attatagcat aaaaaacaaa gaaaactctg tagtattcac
    17401 agtagaattt aaaaattaat tacttattat aaagaatata taactttcaa taatagttca
    17461 ttttaaaatc acaaaaaatt cataatgaaa ctgtattata taaatataaa gaagcttaaa
    17521 accataaaat acaccaacta taatgatgag atttccttac atcctccata taagtcatca
    17581 ttatagtaac ccaacaatta agttactatg aatttaaaaa ataacaccga gcatataatc
    17641 tatgcttagt gttattttta ttttgaaata aaaaatattt aatttattga aatgtataga
    17701 tttagatagt ttaaactata tttaagactt aaaaattata attgatatta caaataaata
    17761 tatgtacttt gggaaaaata aatataggaa gtattatatt tacagaggag gtagttttga
    17821 tggatagatt aaaaagagat atgaaaaata tgaaagaaga tttaaaagaa ggtgttaaaa
    17881 agacagctta tgttatgaaa aatacagctg aagatttgaa agatgatgca caaggtgcta
    17941 tggtaaactt agaaataaaa aaagatgaaa tgatggaaag atatgaacaa aagaaatttt
    18001 ctaaagaatt agagaagcaa atgaagaatg aaatgaaata agcttttatt tatgaataac
    18061 aaattattgt attcatataa aaagtagcca gtaatattaa atagtttatt taaggaaata
    18121 gactttctaa aaataactgt attagattta gaaagtctat ttcaaattag ttttataaat
    18181 agacataagg ataaagtaga tgttatagaa ctagatttta aaaaatagat actaaggata
    18241 aaataaatat tatagaaata tgtttttaag aatatttatc aaataa
//
LOCUS       DAEOTL010000083        18273 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEOTL010000083 DAEOTL010000000
VERSION     DAEOTL010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.083"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            56..1249
                     /locus_tag="KRH82_003118"
     CDS             56..1249
                     /locus_tag="KRH82_003118"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBG8656383.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            1455..2573
                     /locus_tag="KRH82_003119"
     CDS             1455..2573
                     /locus_tag="KRH82_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBG8656384.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYLKLLKYKEAID"
     gene            2704..2949
                     /locus_tag="KRH82_003120"
     CDS             2704..2949
                     /locus_tag="KRH82_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBG8656385.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            2936..3682
                     /locus_tag="KRH82_003121"
     CDS             2936..3682
                     /locus_tag="KRH82_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBG8656386.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLAKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            3965..4840
                     /gene="hslO"
                     /locus_tag="KRH82_003122"
     CDS             3965..4840
                     /gene="hslO"
                     /locus_tag="KRH82_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBG8656387.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            5231..6031
                     /locus_tag="KRH82_003123"
     CDS             5231..6031
                     /locus_tag="KRH82_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBG8656388.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGIHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            6558..8798
                     /locus_tag="KRH82_003124"
     CDS             6558..8798
                     /locus_tag="KRH82_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBG8656389.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEAEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            9210..10745
                     /locus_tag="KRH82_003125"
     CDS             9210..10745
                     /locus_tag="KRH82_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBG8656390.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIATIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMKNGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            10761..11522
                     /locus_tag="KRH82_003126"
     CDS             10761..11522
                     /locus_tag="KRH82_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656391.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            11860..12729
                     /locus_tag="KRH82_003127"
     CDS             11860..12729
                     /locus_tag="KRH82_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8656392.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            13058..13309
                     /locus_tag="KRH82_003128"
     CDS             13058..13309
                     /locus_tag="KRH82_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBG8656393.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            13421..14200
                     /locus_tag="KRH82_003129"
     CDS             13421..14200
                     /locus_tag="KRH82_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8656394.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(14335..14985)
                     /locus_tag="KRH82_003130"
     CDS             complement(14335..14985)
                     /locus_tag="KRH82_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656395.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIAFPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(14982..15485)
                     /locus_tag="KRH82_003131"
     CDS             complement(14982..15485)
                     /locus_tag="KRH82_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8656396.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILSNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(15534..16049)
                     /locus_tag="KRH82_003132"
     CDS             complement(15534..16049)
                     /locus_tag="KRH82_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBG8656397.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            16329..16856
                     /locus_tag="KRH82_003133"
     CDS             16329..16856
                     /locus_tag="KRH82_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656398.1"
                     /translation="MHEQIDYCERKKIRTINIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            16840..18243
                     /locus_tag="KRH82_003134"
     CDS             16840..18243
                     /locus_tag="KRH82_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8656399.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFIFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPGQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
BASE COUNT         6974 a         1960 c         3315 g         6024 t
ORIGIN      
        1 tatgtgcgta aaatctaaca ataagcaata ataccgtaaa tttaggagga ataatatgga
       61 tactttaaag gaacttttta aaataggaag tggaccttca agttctcata ctatgggacc
      121 acaaagagca gcagagagat ttaagaatga aaacccagat gcagaaagtt ttagagcaat
      181 attatatggt agtttggcag ctacagggaa aggtcactta actgactata taattgaaaa
      241 aactatagca cctaaaaaag tcgaaattgt ttgggaagaa gatattataa aagattttca
      301 cccaaatggg atgaagtttg aagctttaga taaagataaa aatgtaacag ctgaatggac
      361 tgtatattct gtaggtggag ggactatagc agaagaaggt caaagaaaca gtaaaagcaa
      421 tagtatatat cacttagata ctatggatga gatagtaaaa tggtgcaaag aaaataataa
      481 gactttggta gattttgtgt tggaatgtga accaaaagac ataaaagatt atataaaaac
      541 tataaaagat gctatgagaa aatctattga tgatggacta agtacagatg aaataatacc
      601 aggcaagtta ttattaaaaa gaagagcaag tacattttat aatgcatata aaaaagataa
      661 gagcttctca acacttgtat atgcatatgc actagcagct tcagagcaaa acgcttctgg
      721 taatataata gttacagcac caacttgtgg ttctgctgga gtaataccag gaatattctt
      781 tgcaatgcag gatttctata attatgatga cgaaaaaata attgaagcac tacttgtagc
      841 tggaataata ggtaatataa taaaaactaa cgcttcaata tctggagcag aggtagggtg
      901 tcaaggtgaa gttggagccg cttgttctat ggcagcagca gcagtagcat acttaaaagg
      961 tggaactata gaccatattg aatatgcggc agaaatagca cttgaacatc atttaggaat
     1021 gacttgtgac cctgtatatg gatatgttca aattccatgt atagaaagaa atgcaatggc
     1081 agctcaaaga gcttatgatg cagctaatta tgcattacta actgatggct cacattctgt
     1141 ctccttagac caagttgttg aaacaatgaa agaaactggt atagatatga tggataagta
     1201 caaagaaaca gctaagggtg gacttgctaa acatttcttc tcttgctaaa aataaaattt
     1261 tccaataata attcctctgt tttgatttat gaaacagggg aattattatt aatggtgaat
     1321 tatttaataa tgcaaaatat ttttatattc aatttagctt tttattttta attagtataa
     1381 catgctatat aatattttaa ttataaagaa atatagaaat attttttaat aaattagaaa
     1441 ttggaggaga ttacatgaga gaggcatcat atttacaaga acaactttat aaacatagga
     1501 agtcattaaa tcctattgca gagattggga gaaaagagta taagacttca aaatatataa
     1561 gagattatct tgataaatta ggaattgagt atgaagttta tttagaaaca ggtatagtag
     1621 gtgtaataga aggtaaaaga cctaaaaaag atattgcttt tagagctgac atagatggtc
     1681 ttcatagtga agaaggggta aaacatttat gtggtcatga tggacatgct actatattac
     1741 ttggattaat tgagtattta aatgataata aagaagactt aaatgataat atagtattta
     1801 tattccaacc agcagaagaa ggtcctgggg gagcaaaagc tttaatagat gaaggagtgc
     1861 ttagaaaata caatattgat gaaatatatg ggcttcatat atatccagag ttaccagaag
     1921 gttatgtagg tacaagagag ggctatttta tggctcaaat aggagatatt gacatagaaa
     1981 tagtgtctaa aagtggacat ggggctatgc cacaaaatgg tattgatggt atagtgatag
     2041 cttcaaactt tgtaagctca cttcaaacta tagtgtctag aaatataagc ccaatagaca
     2101 atgcagtgtt gactattggt agaattgaag ggggagctag aagaaatata atagctgaaa
     2161 atataaagat ggaaggtact atgagatgtt tcagcccaga agtgtatgag aaaatgaagc
     2221 ttagagttag agaacttgct agagggtttg aattggctta taactgtaag gttaatataa
     2281 atattataga tgattatatt gctgttaaaa atgacaagga tttgtatcaa gagtttgtag
     2341 aggctattgg aagtgatact gttgtagagt tagagccact tatgatatca gaagattttt
     2401 cttattatca aaaagaagtt ccaggattat tttttatgtt gggttcaaga aacgaagaaa
     2461 aaggatttgt aaatggtctt cataatataa actttaattt tgatgaaaag atatgtgtaa
     2521 atgcattgaa tgtttattta aaattattaa aatacaaaga agcaatagat taggaaaata
     2581 aattataaag attaaaaagc ataaatacct aaatttaaaa aaagtgtatt aataaatacc
     2641 ccttacatat ttgtataaat ttattttaat tgacaaaaat acaaataaga aggggtgatt
     2701 tttttgaaag aaaaagtaca aagagaaaag aagataacta atggcaagaa tactaaaata
     2761 ttgacaaatg atgatataat gaaatatgag atagcctcag aactaggtct tatggataaa
     2821 gttggtgaac gtggatgggc aggacttaca gctaaggaag caggaagaat tggaggtatg
     2881 cttacatcac gcaaaaagag gcttaaaaag attgtggagg agcagaataa aaaggatgag
     2941 tcaatatagt gattttgcgt ttgtatatga tgaacttatg aatgaagttg attataatgg
     3001 ttgggttaaa tatatagaag atataataga tagtgaaggt gtaaaagtaa aaaatatatt
     3061 ggaattggca tgtggtacgg gtaatcttac aattccattg gctaaaaaaa attacgatat
     3121 agctggtata gatatatctg atgagatgct tagtgtagca agagaaaagg cagaaaaaga
     3181 aggagtagaa ttagttttac ttcaacaaga tatatcagag cttgattttg aaatatctga
     3241 tttggactgt gtactttgtg cttgtgatgg atttaattat ataacttatg atgatgattt
     3301 ggaaaatgta ttttcaaaga catatgaatt attaaagaaa gatggaatat tcatatttga
     3361 tataagttct ttttataaat tagccaacat attgggaaat aacatgtatg gagaaaatag
     3421 agaagatata gcgtatatgt ggcaaaatta ctttgatgaa gaagagaatc taattgaaat
     3481 ggaacttaca ttctttatta aagatgaatg tggaaagttt gaaagatttg aagagataca
     3541 ccaacaaaga gcatatactg aagatgagat agttgatatg cttgaaaaat ctggatttaa
     3601 ggatataaaa tattatgggg attttacatt tgacaaacct agtgaagaaa gtcaaagaat
     3661 cttctttgta tgtaaaaaat aagatattct tgactatata agataattat taaaaataac
     3721 catgatataa aaatatagaa aatgcagttt tatagattaa aagtaaagtg atgatacttt
     3781 atgactttta ttttttaata attataaagt tctatagata aaaattaaaa tatagtaact
     3841 attacttagt aaaattaaaa taaaatgggt tttgcccaag gttaagatag ataagtattt
     3901 atagataaat taaggtagta atataataaa aataagacaa ttaacgggac atggaggaat
     3961 attaatgaga gattatgtac taagagcgac atcaggaaat ggtcaagtta gagcatttgt
     4021 cgcaactact agaaatacag tagaagaagc tagaagatta catgaaacta caaaagtagc
     4081 aacagcagca cttggaagaa cattaacagc cacatctata atgggattaa tgatgaaaaa
     4141 tgatagtgat aaattgactg taataataaa aggtggaggt ccaattggaa ctattatcgc
     4201 cacatcagac tctaagggaa tggtaaaagg atatgtagga aatccacaag tagaggttga
     4261 agactatcca aatggaaagt taaatgtagc agcagcagta ggtacagaag gtgttgtaaa
     4321 agttataaaa gacttaggtc ttagagaacc atataatggg acttatccat tggtaagtgg
     4381 agaaattgca gaagacttta cttattattt tgctgtatca gagcagactc catcagtagt
     4441 agctttaggt gttcttacaa aagaagatga agtagagttt gctggaggat ttatagttca
     4501 attaatgcca gatgcagaag aagagactat tgctaagtta gaggaaaatg tagctaaatt
     4561 accttctata actaacatgt taaaagaagg aaaatcacca gaggatatat taaatattgt
     4621 tttggatggt ttggaaccta aaatacttga tacctgtgaa gttgggttta tgtgtgaatg
     4681 ttcaaaagaa agagtaaaaa ctgctttggt tgcaattggt aaaaaatcat tggctcaaat
     4741 aatagaagaa gataaaaaag cagaagttgg ttgccagttc tgtaataaga agtatatgta
     4801 tagtgaagaa gagttgcttg aaattttaaa ggaaatgtag actataaaaa tagttgtatt
     4861 gatataagta atgttatagt aatatagtaa agtcgtattg atatagtaat taaagtataa
     4921 tttattaata atagacatat ttatattaaa aaataagttt aataaatttt taagcttaat
     4981 aaattttaag aattaagaag ctttctggct gtaatgtttg caatgttgca gttagaaggc
     5041 ttttttattt tattatagtt cgtgtcaaag attgtatgaa acaataaaat attgtaaaat
     5101 aatttgtata tttagacttg atttacacaa aggtttataa gatatttgag ttgattatac
     5161 gaaattctat gaagtagtaa ccctgtgact ttaatcatgg gaggttcaga agaaggagaa
     5221 aattttaaat atggaaagta aaacgaagta cataggaata agtatattaa tattattgat
     5281 gatattttta attgcaaaga attttaacgg aaaacttgaa atacctattc ctgagagtaa
     5341 tagtagaaaa tttaaatcag cagcagtgtt ttatcctcaa catcaagatg atgaggtttt
     5401 atggggagga agtgccattg tagatgctat aaaacagtgt ggtgttgata atgtatatgt
     5461 ggtattagta tcagatggtt ctggagttaa cgttttcaaa gctaacacaa aatttagaaa
     5521 tttaactagg aagcaaaagg aagaacttag aaataacgag tttaaatcag ctttgagaga
     5581 gcttggagtg aaacctcaaa atgtgattat acttgcagat atagataaaa aggaaggcat
     5641 acattatgaa ttaatggaaa agactatatt ggattttgaa cataagttta aaggcaatgt
     5701 gacccatata gcccatcact ataagtatga tgaccatata atgcatagaa agaatgggga
     5761 agttttaaag aaacttaaac gtgaaggtaa gataaaagat gacttgtatt ttgttaagcc
     5821 aaaatatgta aagtatatac caagaaatga aagagctatc tataaagcaa tggattttga
     5881 tgactacaat aaggttaaga gtgcttgtta tgaatataag gttgtaaatt caaagcgtaa
     5941 aatgtatggt ataggatata tttcggcaca tagttatttt gaacatcttc taaatgaccc
     6001 tgaacttacg tctgtattaa gtgaagatta atttcttata agtagtaagt tatgtttgat
     6061 aagttgattg gaattttcta tagttttgaa ggtattggaa atttagtttt atttaaagat
     6121 ttaaagatag aggtttttag tgtttaaaat tttaaagtta agttgagtaa ttgtatagaa
     6181 ttatttgtga aagaagaaac agtgtaaaac atagtatctt atttatggtt ttaaaatcat
     6241 aggcaagata ctttttttat gtaactaata ccattttgag attattaact taagaatttt
     6301 atataattta acactcatat ataatgatga tatttaggta gaatagatgc aattacgctt
     6361 aaataaaata actgtatttt ttataaaaat caaaccctac actatactac cagataaaat
     6421 ctacatgcta taatttgacc tgtgtttata aaaaaaggag taatctaata aaatagtatt
     6481 tcacttatgt ataactaaca actattatta cgattttctc taaataattt aaagaaaaat
     6541 aatgcaggag gtaaaatatg aacaatgaat ttataatttt aaaaggttgc aaagagaaca
     6601 atttgaacaa tatttcctta aaaataccaa aaagaaaaat aaccatattc acaggggtgt
     6661 cgggttctgg aaagtcatct attgtatttg agacaattgc aaaagaatca caacgccaac
     6721 taaatgaaag gtttagtaca tttgtaagaa gttttttacc taagtatgga gaggttaaag
     6781 ctgattgtat agaaaatttg tcaacaccaa ttatcataga ccaaagtaga cttggtggaa
     6841 attcaaggtc aaccctaggt actattacag atgtaaattc ctttttaaga gctttatatt
     6901 caaggtttgg tagtgagtat ataggtaatg ccaatatgtt ttcttttaat aatattgatg
     6961 gtatgtgccc acactgtcat gggcttggaa aaaagctagt tcctaatatg aaccaaattc
     7021 ttgatatgaa taaatcatta aatgaaggtg ctatattgct ttcagggttt ggagtgggtt
     7081 cttggcattg gaatatattc gctgaatcag gattttttga tattaataag aggatatgtg
     7141 attattcaga agtagaattg gaaaagtttt tgcatggtaa agcagaaaag attaagatag
     7201 aaaatgctgg tcaaactaac atgacatatg agggactaat ggttaaattt aatcgcctat
     7261 acttaagtag agagggagaa atatctgaag ctactaagaa aaaattgagt aaacttctta
     7321 tagaagatag atgtcctata tgtgatggaa gaagacttaa tgaaagagta tataggtctt
     7381 taattaatgg ttataatata gcagatttaa ctagtatgca aattgatgaa ttggctgaag
     7441 ttattaaaag tatagatgag gcagaagcac aacctttaat taaaggaata atagaaaagt
     7501 taaacagtat catagatata ggtcttggat atttaacact ggatagagag acatcttctc
     7561 tatcaggagg ggaatctcag cgtataaaga tggttaagta tttaaatagt aatcttgtag
     7621 atttaatgta tatttttgat gaaccaagtg taggacttca tccaaaagat gtgtataaat
     7681 taaataatct tttaaaaaaa ttgcgtgata aagggaatac aattatagtt gttgaacatg
     7741 acccagatgt tattaagatt gcagaccata ttgtagatgt aggaccaaag gcaggtaagt
     7801 atggtggaga agttgtgtat gaaggcagtt atgaaaatct acttacaagt ggtactttga
     7861 cagggaatgc tttaagtaaa tttcttccta ttaaagaaag tgtaagagaa catagtggat
     7921 atttagaagt taaaaattgt aataaaaaca atttaaaaaa tgtatcgatt aagataccta
     7981 aaggtgtatt gactttagtt actggagtag caggagcagg taaaagtacg ttgattaagg
     8041 atgaattttt aaagcaaaat cctagtgctg tacttataga ccaaagccct gtttcagcaa
     8101 attcaaggtc gagtttggca acatatagtg gaattatgaa caacataaga agcatatttt
     8161 caaaaacaaa tggcgtaaat gcttctttat tcagttcaaa ttcagaagga gcttgtgata
     8221 actgtaaggg ttctggaata gtagaaatga atcttgcttt tatggagagt ataaagagta
     8281 cctgcaatgt ttgtgaaggt aaaaaattta aaaaagaagt tttagaatat aggtttcaag
     8341 ggaagaatat aattgaagtt cttgaaatgt ctgttttaga cgcaattgag ttttttaatt
     8401 taaaacagat taaaacgaaa ttacaatgta ttgaaaaaat gggtattgga taccttactt
     8461 taggacaaac tcttgatact ttgtctggag gagagtgtca aagattaaag cttgctagtg
     8521 aattaaataa ggaaagttca gtgtatatat tagatgaacc aacaacaggt cttcatatgg
     8581 ctgatattga gaattttata agtataattg aagagattgt agataatgga aatacggtca
     8641 taataattga acacaatata gatgtaatta aaagagctga ttggattatt gagctgggac
     8701 ctgaaggagg aacaaaaggc gggagagtaa tatttgaagg tattccaaaa caattatgta
     8761 acaataaaat atcattaaca gcaaaatata tagtataata aataaaatat aataaaatta
     8821 taatgatatt ttaataaata taatgggtat ataaaatgat aattaaactt aacagtaata
     8881 aataatgtga gaaatattca aatttaatta aataaagtgt cagaaatttg tttaaatttt
     8941 agtattttaa cggttctgac cttttttctt atttttatgg agaatatcga ggatggagtc
     9001 tctaatagtt acttttttgt gtctacttgc aagtttgatt aaaaaatggc tatacacact
     9061 tgtgacttca gtcatgggag gttccgatta taatcttaat ataatttgtg aaataatttg
     9121 atgacgattt gctgatgtat aaacaataaa gattaactac attaaaattt aaatcttgtt
     9181 aagtaaaact tataaaagga gagagatgga tgataaatga tattctaacc ttattatctg
     9241 aaagaagtga tttttttata aagctatcca tagaacattt gatgatttct attatttcta
     9301 taataattgc gattgttttg ggtggtataa ttggtattat tgtaagtgaa tttcataatt
     9361 cttctaaacc tatattggga actatcaatt ttctatacac cattccatct atttctatgc
     9421 taggatttct gataccattt tccggaattg gaaatactac tgctgttatt gcacttacca
     9481 tttatgcatt attgccaatg gttagaaata catatactgg aattactaat gtggataaaa
     9541 atattcttga agcagctagg ggaatgggaa gtacagattt tcagatattg tataaaataa
     9601 aacttccgtt agccctacct gttattatgt ctggtattag aaatatggtg attatgacaa
     9661 ttgcattagc tggtatcgct tcatttatag gtgctggagg cctaggtgta gccatatata
     9721 gaggaatcac gacaaataac acaataatga caattactgg aagtatactt attgctctat
     9781 tagctttaat atttgatttt attttagggc tggtagaaaa attttttcaa cgaaaaagaa
     9841 aaaagaaaaa tagaaaaaaa gtttttgcca ttctaggaag ccttattctt atagcaacta
     9901 tctttacgtc ttatttattt aatccttcaa agactcaaac tattcatatt gctactaaac
     9961 ctatgactga acaatatatt cttggtgaga tgttggatat tttaattgaa aaaaacacag
    10021 gtctaaacgt ggaaattaca caaggtgtag gagggggaac atctaatatc cagccagcta
    10081 tgaagaatgg agaatttgac atttatccag agtatacagg tacaggctgg aatatggtac
    10141 ttaagaaaaa tgaattatat actgaaagta tgtttagtaa actacagtcg gaatacaaaa
    10201 ctaaacttaa aatgcaatgg actggtatgt atggtttttc taatagctat gcattagcag
    10261 ttagaaaaga agttgcagat aaatacaatt taaaaaatat aacggactta aaagatgtat
    10321 cttctaaatt gacatttgga gctgaatatg acttttatga gagagaggat ggatatactc
    10381 cattgtgtaa tacatatgga ctgaacttta aagatacagt tgatttagat attggattaa
    10441 aataccaagc tatcaatgaa ggtaagattg acgtaatgcc tatatttaca actgatggtc
    10501 agtatagtgt ttcagatgtt gtagttctaa aagatgataa aaatttctac ccatcttatc
    10561 aatgtggaaa tgttgttcgt ttggaagtat tagaggaaaa tccagaacta tcaaaggtat
    10621 ttaagatggt tggagatatt ttgactgata aagaaatggc taaaatgaat tatgacgtag
    10681 aaaacaacaa tttagaacct agagaagttg ctcgtgagtt tctgaataag aaaggtcttt
    10741 tataaattgg aggaaatata atgacaccta ttatacaatt taaaaatatt aaaaaacaat
    10801 ataatgataa aactataata gataatctta atttagatat agaaaaagga gagtttttga
    10861 ctgtaattgg ttcatctggt tctggtaaga caacactctt aaaaatgatt aatggtctga
    10921 ttttgccaga tggaggaaat attttgataa accaaacaga tatcaaaaac gaggacttaa
    10981 ttaaattaag aagaagaata ggatattgtg tacagggaag tgttcttttt cctcatatga
    11041 ctgttgaaga aaatatttca tatgtaccaa atctcctaag taaaaagaat aaattagaag
    11101 taaaaagtgc tgtaaacaaa tggatggaaa tagtgggatt gccaaatgat atgaaagtgc
    11161 gttacccatc agaattgtca ggtggtcagc aacaacgtgt agggattgca agagctttag
    11221 cttcttctcc agaaatttta ttaatggatg aaccttttgg tgcagttgat gagattacac
    11281 gaaagcaatt acaaaaagag ataaaagaaa ttcataaaaa aacaggagtt acgattatct
    11341 ttattacgca tgatatttat gaagctttga ttttgggaac aaagactttg gtattaaatc
    11401 atggagttgt tcaacagtat gatactcctg agaatatttt aaatactcct gctaaccaat
    11461 ttgtagacca gttattgaat ataagaaaat ctataataga tgatgataat ttaaaagaat
    11521 aaatttaaat ttaaaatcaa attgttgtga taaaaactat tgatttagag ctaacttcaa
    11581 gttgtatact tgaagtggaa aagttagatt aaggtataga agggaattta gcagttggct
    11641 gtagacaagg taactgctga aggtgatttc aataaatggc tagaacctgt atctgttgaa
    11701 gattataata aattgaaata agaagctcaa tatacagagt agataggcac ttcaaataga
    11761 agtgtctttt gtgtgccata aaataaatca aaatattagc aaagaatgtg aaaaacaaaa
    11821 taaaataata tgctatcttt aaaataggag gggtgctata tggataacaa tttgattacc
    11881 attgaaaaaa ctttagatta tatagaaaaa catcttttag atgagatgtt agatttaaat
    11941 gtaatttcta aagagatagg ctattcaaaa taccatttac atagaatgtt tacatcagtt
    12001 gtcggattta gtgtacataa ttatatacaa agacgtagac ttactgaagc agcgagaatg
    12061 ctaattttta cagaaaaacc aattattgag attgctttaa tctcggggta tgacacacaa
    12121 cgctcttttt caagagggtt taaaaaaatg tttaaacgta gtcctaattt ttttagaaga
    12181 catcaagatt ttttaccact acaattaaaa tttgatattc ataatagaaa aaaattacgt
    12241 ggagatatgg ttttagatgt taaaaaagtt aattgtgcag atataaatat tgttggctat
    12301 tctggtaaag taagaaaagg atttcatatt attggaaaat gttggaggga tttgcataaa
    12361 aataaagaga tgatagaaaa taaggtagat ttaggttttt taattggagt tagtgattat
    12421 agcaatttta aagagattga gaatactcct acatttacat acattgcagg tgctcaagta
    12481 gctacttttg gcaaattacc taatggaatg gaaaaattcg tattaccgaa aagtaattat
    12541 attgttttta cttttattgg gaaaaatgag gatagtatgc aaaatgttgt agaatatatc
    12601 tatcaagaat ggttccctaa ttcaagttgc cagtttaatg aaaataattt atatgacttt
    12661 gtaaaatatg gagaaaaaac tgatgagaat ggtttgagtg aaattcagtt ttgggttcca
    12721 atcatttaaa agaaggtatt atgtataaag tagatggatt tatataggca aagttttaca
    12781 gcagtatgta tttataaata atttatagtt tgtaggaaag aaataatttt actataagat
    12841 tatgataaaa tacacaatac tatgacaaaa tagtgttaaa taatagattt aattttgcat
    12901 aggaaaagtt ctataatggt gtgtattcat aaataattta taatctgtag gaaagaaata
    12961 gttttactat aagattatga taaaatacac aatactatga taaaatagta ctaaataata
    13021 gatttaattt tgcaaaggat aaggtgtttt aataaaaatg aatgtagaaa acgaattact
    13081 taaaaaccta gatagattgc atacaacaga gttaggcgtt gtaagaatta agaaaaatct
    13141 ttctttggag acaaatgatg tagtaaactg gtgtaaaact aaaatagaat ctccaaatgc
    13201 cattattaat agaaagggaa aaaactggta tataagtgta tatgattgta ttataacagt
    13261 aaacgctcac agttatacaa ttattacagc tcataaagaa aagaaatgaa ttgcaaaata
    13321 caaaggtcaa aagtattttc cactgtttgt agtacctatg aagaagtata taaaataata
    13381 ttacttttga ataataattt aaattttgga ggttgaaaaa atgaatgata ctgtaaaaga
    13441 aaaattggca gagtcactaa cttctgatac tactgatatt ttaccttatt tgccttattt
    13501 attacaagat ttttgggaat taggaagttc accagaacaa atgttacaat tatttagaaa
    13561 gcatatacct tttaatgagg atacaaaagt tttggattta gcttgtggaa aaggtgctgt
    13621 atctgtgaag cttgcaaaag agttgaatat acatatcaaa ggtattgatt tgatacctga
    13681 atttattgat tatgcgagaa gaaaggctat tgaatataag gttgatgctt tgtgtgattt
    13741 tgaaatgaat gatgctaata gttctgtaaa aattgagcac gattatgatt gtgtgatttt
    13801 tggagctgta ggggatattt taggtaatta taaagaaact ataagtaagc tattacctac
    13861 aataaaaagt aaggggttca ttttaattga tgatgcatat gtagtagata aatctacaaa
    13921 tgaacagctt aattttgaga gggtgtatcc cacttacaat gagtggtgta tattgttcaa
    13981 agaattaggt ctgaaactaa ttgaatgtat accatgttta gaacttgaaa atgatgttga
    14041 agaggaaatg aactggatta taactcgtgc aaatgagcta attaaaaaat atccttctca
    14101 aaaagatatg tttgaacaat atgttattag ccaaaaaaat gaatatactg atttacagca
    14161 ggaccttgtt ggagcaactt ggattttaca aaaagaataa gataaatatt agactagata
    14221 atcaatgttg tagtgaatta tcccatgtct agtgaatata aataacataa aaaaccgtca
    14281 agatgaatag tttattcgtg cttgacggtt tttagtattt gttgaagtaa aattttattt
    14341 ctttagtata tcacttttag tcaatccatt tgatttagcc tgagtattcc attgatgatt
    14401 ccccataagt ttatatagga atctagggaa gttaggtgaa ataaaaatag tacttttgtt
    14461 ggaatcatct atatgtatat tatcactaag tatatttttt gaaagttctt ttaatgcaat
    14521 tcctaaatct tttttaggtc ctttacccaa aggtacggat tctagtgaac caaacatctc
    14581 cccagctcca attccaatac cttgaaccca tgtaaagttg atttttttac accaatgctc
    14641 tatcatttga attgccaaat gattatgttc accttcattg aatccacagt taactattgc
    14701 atacactgga ataggttttt tattttgtgt ttttaaaaat ttttcacatt tctctaaaaa
    14761 atgaagtaaa tgagacggaa taccatctac ataaagagga aatgctatta ttaatctatc
    14821 acaattaagt atggcattaa gagcgtcagg atacttagat gtgctatcta ctttaaatgt
    14881 aaaaacttta ttatcatttt gaataagttg ttttaattca gataaaaaat actgtgaatt
    14941 atttttattt acttttggac taccatttat cattactata ttcatatgga ttcacctctt
    15001 atatcctgta tattttcata gaaacaaaca gagtgttctt ttatattgaa atttatagca
    15061 tttccattta ctaatttcgt agcagtttct ttttcagctt ctgtaataca atctccatag
    15121 aatatagctt ttaaatttat ctgtttatca tatctgcttt tatgacgcat catattatct
    15181 tttattacaa agtatggaag aatataatta atgcttttat caagtacgtt tttgacaaaa
    15241 gggctaaacc ctccgtaaca gcatctgctt attataataa ttccatcaga ttcatttata
    15301 agtttaccca tgttgctgta ataatctttt acaacacatt cagaaggagt tttaatccag
    15361 caaccaaaac aaccaataca tttatggatt tcttttgtgt ttgaaagtat ttttatattg
    15421 tcatcaagtt tgggtaataa cttttctaat tctttgtcag ttaaatcatg tattaaaagc
    15481 ctcataaagt ccatctcctt ttattatgta tgtttacttc taaaaattat atcttataga
    15541 tttttcagta aatctttaca ccaattaata acaaaattat aatagtcaac tccataaatc
    15601 attgttgcat acatatatgt atattggtca acacaatgat tttcttctgc atcatttttt
    15661 tgtttactta atttatttag aagtaattct acttcagtta ttaacatttt taagtttgtt
    15721 tcaattattt ctttgggtag atacttgtaa aagaatatat taacaaggtg gtcttgcttt
    15781 gttttagaaa aatttatagg tttctttaac cattcaagaa atacttcttt accagtatta
    15841 gttatggaat atagtttttt taatttgcta ccatctataa cttcgtgata gtgtatatat
    15901 ccttttgttt ctaatctttt aagtgcagga tagatacttc caaagctggc gtcaaaaaag
    15961 tacgaggtac tttctgacat tatttgtttt aagtcgtatc cacttaattc tttttccatt
    16021 aaaaatccta aaataatgta ttctaacata ttacctcctg atatcaatta gatatatatc
    16081 gattcgatat atttattatt acagataata aatcttacgt caagatgctt tttaaaataa
    16141 gctaaaaaga attaggagtt attgataaat atgcaaaaaa attaatataa aaggtaatta
    16201 aatatcaatg aagatttaaa aatagttaaa tcaaagtaag agtctaatat ataaaattta
    16261 tagtaacttt atggtttaaa tataaacttg tgtgctattg acaaagtata aaattagcag
    16321 taaaataatt gcatgagcaa atagattatt gcgaacgcaa aaaaataagg acaataaata
    16381 ttaaaggaga gaatatgaga gagctattaa aatgggtttc cattataaat agatacaata
    16441 caaattatat tgacaggaaa ttggcggata ttggaatcaa taatagccaa tatttttatg
    16501 tattacacat atgtaataat ccaggtatta cacaggacac tatatttgag aaaattcttg
    16561 tgaatcctag taatataaca agagctttgg caaatttaga aaaagaaggc tttataacaa
    16621 gagaaccagg tgtaaaggat aaaagaacat ggcatttata tcctacagaa aaatctttag
    16681 aatgttatga tgaaatacta aaaataacaa atgggtatgt tgaggagttg ttgagttcat
    16741 ttgagaaaga agagcaagag ttgtttatgt caatgttaaa gaaagttgca tttttggcta
    16801 ttgatatgaa tgaagaagca aaattggagg cgaaggaaaa tggaagaaaa atataaggag
    16861 ccattggaat atgaaaaggt ttcaaagtta ttaactaagt acgcaattcc tagtattata
    16921 gcaatgttag taagtgcttt atataacatt gttgaccaaa tatttattgg gcaaggtgtt
    16981 ggtgtattgg gtaatgctgc tacaaatgtc acttttccac taacaacaat atgtaccgca
    17041 attgcattat tgttaggaat tggaggagcg tctaagtgtt cattggaatt aggtgctaaa
    17101 aattcagaaa aagctacaaa agcagcagga aattctatat gcttgatggc tgtttttgga
    17161 ataagtttat ttatagtagt atcaatattt ttaacaccac tattaaaatt ctttggctct
    17221 acatcagaaa tactacctta tgcacacaca tatacaaaaa ttacatcaat tggattacca
    17281 tttcttataa tgtccactgg aatgagtaag ttgatacttg cagatgggag accaaaagct
    17341 tctatgtttt gtatgttaat aggagcagtt attaatacaa ttttgaatcc attattcatt
    17401 tttattttta atatgggaat tgctgggtct gctttagcaa ctgttattgg gcaacttata
    17461 tcttttggaa taagtgttca ttatataaag aattttcaac atattaaatt acataagaaa
    17521 agttttaaat tagatagtat aatttataaa catatatttg cgctaggttc aagctcatgt
    17581 tttaatcaat tagcaatgac tgtaacacag atagttatga ataatacatt ggcatattat
    17641 ggggctaggt cagtttatgg aagtgagatt ccacttgctt gtgtcggtat cattattaaa
    17701 gtaaatatga tttttatatc tataattatt ggtatatcac aaggtatgca accaattata
    17761 gggtataatt atggggctga aaagtataat cgtgtaaaag aagcatataa gtttgcagtg
    17821 ggaagtgcaa ctattatatc tgttattgca ttcttatgtt tccaattctt cccaggacaa
    17881 attacgtcta tatttggtaa cggaaatgag acttatttta tatttgcaga acattatttt
    17941 agaactttct tgttcttaac atttataaat ggtgttcaaa tagtatcatc aactttcttt
    18001 acatcaattg gtaaatcagt gttgggactt tttacttctt tgactcgtca aattttattt
    18061 ttaattccat tgatagtaat tttaccaatg tttatgggaa ttgatggagt aatgtttgca
    18121 ggaccaatag cagatgcagc agcggcaatg gtatgtatat actttgcagt tcatgaaatg
    18181 aaatcattga ctataaagca aaataatttg atgagtaacc ataataagat tgcagaggta
    18241 taagacaata tttaagaagt atagaaaatt aat
//
LOCUS       DAEOTL010000084        18216 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEOTL010000084 DAEOTL010000000
VERSION     DAEOTL010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18216
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.084"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..224)
                     /locus_tag="KRH82_003135"
     CDS             complement(<1..224)
                     /locus_tag="KRH82_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8656400.1"
                     /translation="MEMKYVVPDMTQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKL"
     gene            complement(463..3507)
                     /locus_tag="KRH82_003136"
     CDS             complement(463..3507)
                     /locus_tag="KRH82_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBG8656401.1"
                     /translation="MKKMLKRLCTGFLALATIVTALPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGMMKVEGETAYCIDINTDFKNGYKTRTDASSRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSISGATYGVFSDKDCTKQLATLTTDENGNTNVVEVKAGTVYIKELSAPAGYKVDKT
                     VYPLTIKAGETATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAKFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDETTHYITKLANAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPKGYLLDGAYMQAGDKSEQIKGVYVTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGNFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMCCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADEEEMKVEISYTFNASALGGKNPVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LKGLEVGTKYKLVGWQMLKAENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDKPKKVTEHKDIEDEGQTITFKEKPEEPEKPETPQTPEKPN
                     RPSDSPKTGDSTNVMAFIVMLFASAGGLAGTYLYKRRKMKKS"
     gene            complement(3752..5116)
                     /gene="rlmD"
                     /locus_tag="KRH82_003137"
     CDS             complement(3752..5116)
                     /gene="rlmD"
                     /locus_tag="KRH82_003137"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBG8656402.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIQDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSENLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETCVLLQ
                     RRTM"
     gene            complement(5291..7051)
                     /gene="pyk"
                     /locus_tag="KRH82_003138"
     CDS             complement(5291..7051)
                     /gene="pyk"
                     /locus_tag="KRH82_003138"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBG8656403.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(7103..8062)
                     /gene="pfkA"
                     /locus_tag="KRH82_003139"
     CDS             complement(7103..8062)
                     /gene="pfkA"
                     /locus_tag="KRH82_003139"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBG8656404.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(8271..11840)
                     /locus_tag="KRH82_003140"
     CDS             complement(8271..11840)
                     /locus_tag="KRH82_003140"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBG8656405.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(11997..12944)
                     /gene="whiA"
                     /locus_tag="KRH82_003141"
     CDS             complement(11997..12944)
                     /gene="whiA"
                     /locus_tag="KRH82_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBG8656406.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(12961..13386)
                     /locus_tag="KRH82_003142"
     CDS             complement(12961..13386)
                     /locus_tag="KRH82_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBG8656407.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(13455..14561)
                     /locus_tag="KRH82_003143"
     CDS             complement(13455..14561)
                     /locus_tag="KRH82_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBG8656408.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(14573..15430)
                     /gene="rapZ"
                     /locus_tag="KRH82_003144"
     CDS             complement(14573..15430)
                     /gene="rapZ"
                     /locus_tag="KRH82_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBG8656409.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(15461..16174)
                     /locus_tag="KRH82_003145"
     CDS             complement(15461..16174)
                     /locus_tag="KRH82_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBG8656410.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(16178..17092)
                     /gene="murB"
                     /locus_tag="KRH82_003146"
     CDS             complement(16178..17092)
                     /gene="murB"
                     /locus_tag="KRH82_003146"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBG8656411.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(17365..18135)
                     /locus_tag="KRH82_003147"
     CDS             complement(17365..18135)
                     /locus_tag="KRH82_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBG8656412.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKVDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT         5192 a         3762 c         2260 g         7002 t
ORIGIN      
        1 agttttactt tctgctcata cttgaaatgc ttttcaccag cctgcacggg aatttctacc
       61 acaacatttt cacctttctg tacgtcagaa taaaggttat agcttcgtct ggctaaaacc
      121 ctgcggttat ttttatctct ttcaaagact ggctcacttt cgcctgcaaa ttcaagagtt
      181 ccaaaagact gtgtcatatc tggcacgaca tatttcattt ccatagtgtt ttacctcgtt
      241 tctttctatt tttgataagt tgattgattg tgatttctta ttctggcggt tgggtaagta
      301 ccagcaatcc cccagatagt aaagggtaaa atcaatgctt acgcaccctt gactatccgt
      361 gttcttgcag gttgtagaca gacaagccag aataagcgga agtctaccgt ttgaccgctt
      421 cggcggagaa cgtgattttt ctttcatcat accgttaccg ccttatgatt tcttcatttt
      481 acggcgtttg taaagatatg ttccagccag tccaccagca gacgcaaaca acatcacgat
      541 aaatgccatt acatttgtac tgtcgcccgt tttgggactg tcgctaggtc tgtttggctt
      601 ctctggtgtc tgtggtgttt cgggtttctc tggttcttct ggcttttcct taaaggtaat
      661 cgtctgtccc tcgtcctcaa tgtctttatg ctcggtaact ttcttcggct tgtctggatt
      721 gcttaaatcg tataattcct caaaagttac aagctgtttg ccgtcaaggg aagtagcgtc
      781 aaaggtaaag gcaacttcca ctttcatagt ttcgctgtca gcggtaaagg tataatcact
      841 ttccacacgt tttccattga taagaagctc tgcattttct gctttcaaca tctgccagcc
      901 tacaagttta tactttgtac cgacttctaa gccctttaag gttacggtat caatgattgt
      961 aacgtctttt cctgcttcaa gctctttgtt gccgtccttg tccgtagcag ttgtatgaat
     1021 tttgatgata cgctctgtga ttaaaacagt ttgcccgtcg tcctcaatgt ccttatgttc
     1081 cgcaactttc acgggttcgt ctggattgct caaatcatac aattcttcaa aggtaacagg
     1141 gttcttgcca cctaaagcag acgcattgaa tgtataggaa atttccactt tcatttcttc
     1201 ctcatcagcg acaaaggtat aatcattttc tacacgtttc ccgtcaatga taagctcggc
     1261 gttttcttcc tttaacatct gccagccttt gagctgatat tttgtgcctt ttgtaagtcc
     1321 gtctaatttg acagtatcaa caatcgtaac ctcttttcct gcaaggatag tcttttcgcc
     1381 gtccttgctg gttgctgtgg tatggataga gatttctttt tcgtattcat cagtcaaagt
     1441 ccctaaatca atcacaagat tatttcttga taccacgatt tcaaaaggtg ggataagctc
     1501 aaagcctttg ttactatcac aacacatttc ttcaattatg taggtatcat aaggtaacgc
     1561 acccttgctg tcgtctggtt cagaagtccc aaaccataca ccgtcctcgc tggtctttcc
     1621 tgcgttggta ttgtgcttgt gagaagccca gtcagcagaa gtggagaatt gcccgttatc
     1681 gtcagttact acgacatgac tttctcccgt cgtcttgctt gtgatccgaa acggaacatc
     1741 agcaagacgc ttgtgtgtgc ctgcaccgat ttttacgccc tcaatatctc cacgcttaat
     1801 ctgattgtag atagaatggg cttcgtcggt taagtccacg atttttccat tttctgtgat
     1861 tgcaaaatca atcggttttg caccgtctgt caaatatccg tcgggtgctt cactctcaac
     1921 gatacggaag tttccataag gtaaaaggtc agcagaagta gaagcgacac cctcaatatc
     1981 tgtacgaata gtttttacca cttcattttt cttgtataac ttgccttcaa ccaatactgc
     2041 attatcattt aaggaaatga tgtcaaaggc agtatctttc aaggtagcac ttccttgtgg
     2101 tttcgtatcg cctgtttcta aatctcgttt ctggattttc acaccgccac ggataacctt
     2161 gtctgatacg gaaaactggt tacttccagt caatacggca aggtcgccgt cctcagtaat
     2221 ctgtgttaca tatacgccct ttatctgttc ggatttatcg ccagcctgca tatatgcacc
     2281 gtcaagtaag tagccttttg gagcttttgt ttcctcaacg gttagtgttc ctaaaggaag
     2341 aaccgccttg ccgtcctgca tatagaaact gtcgccagat accttgtatg cgttcgctaa
     2401 ttttgtgatg tagtgggttg tctcgtcgct gtcagtttca gcgattgtct ttgtaaccca
     2461 tgtacgagta gcttcggcag ggagattgtc tttgttatag aagcctgcat aatacttcca
     2521 tgtaaatttc gcacctgcta gagaagcgtt cccttgcgga ttgtctttct gtgtttccat
     2581 atcaatcttg aaaagctcaa tcaaagtatc cgttaccttt ggtgtatcag atacttttaa
     2641 ggttgctgtt tcgccagctt tgattgtcaa tggatagact gttttatcca ctttatatcc
     2701 tgctggtgca gaaagctctt tgatatatac tgtccctgct ttgacttcta caacattcgt
     2761 atttccgttt tcatcagtcg taagggtggc aagctgtttt gtgcagtcct tatcagaaaa
     2821 gacaccataa gttgcaccag agatagagta atttccgtta ccgtctgtaa tgctggtatt
     2881 actggaagtc ttttgcagct tcgcatttcc gacattcagc ttcgcccaga attgtcccaa
     2941 ttcctgcccc tcgccagagt agatataacc gccacattca tagcgtcctt tattttcttt
     3001 gacaaaggct tttgcaccag cgaaaacttc gtcctgcgta gcttttggta tttcatcata
     3061 agaagctcgc acgttgtcgc attgccagcc aagatgtacg cttaatctct gccagacaac
     3121 acattgttcc aacagataaa cttgtttgta attcaattcc ttgtgagctt cgccatactg
     3181 tttgacatac tctaaggata acgccacatc tgaaatctgg tcggcactca tgcgtgagct
     3241 tgcgtcagtt ctggtcttgt aaccattctt gaaatctgta ttgatgtcaa tacaataggc
     3301 agtttcgccc tcaactttca tcatgccctc attgaatgta gaaccgatag aaccgtcatt
     3361 cattactttt tcaacgatac cgacacgctc ttttgactcc gtccagtatt gcttgctttc
     3421 tgcatgaacg ggtgtagtcg gtaaagcagt aacgatagtt gcaagagcta agaagcccgt
     3481 acacaatcgt tttaacatct ttttcataaa tctaatgctc ctttcatttt gggtataaaa
     3541 atagacgctc atttctgaac gtcttacatt taaaaaggga tactatttta acaagtaccc
     3601 ctaaagttta gtatttaatt gtttgtgttc ccacactcta tatcaactac taccgaaaca
     3661 ttgatatagt tttttatctc tttatttctg attttatcgc cctcgctcgt aaagacgata
     3721 tgcttgaaaa agtgcctaaa attaaggatt tctacatagt tcgtctttgt agcaacacac
     3781 aagtctccac atgtgtagaa tgagggaaca tatctacagg ttgtgcctca acacatttaa
     3841 atccgtgaac atttagatag tctaaatccc ttgctaaagt agaaggatta caagaaacat
     3901 agacaattct ttccggattc attgaaacaa tagtctctaa taccttttcg tcacatccct
     3961 ttctaggtgg gtctacaact actacattgg cagtcttacc ctctctatac atcttaggta
     4021 caatttcctc tgcctttcca acataaaatt cagcattatg tatattgttt aatttagcat
     4081 ttattttagc atcttttatg gcatcatcta taatttctat tccataaacc tttttagcct
     4141 tttgtgccaa aaataaagat attgtaccta tcccacagta aatatcaaaa acagtatcag
     4201 tatcatttaa atttgcatat tcaagagcct tatcatacaa tactttagtt tggacagggt
     4261 ttacttggaa aaatgataat ggtgaaatct caaacactaa gtcacctata taatcgttta
     4321 tttttccatc tccatatata actatatttt ctcttcctag aatagcattc gtatcttttt
     4381 gatttacatt tacaaccaaa gtcttaaatc caggtatatt ttccttaagc actgaagcta
     4441 attctttaag atatggaagt ttgtttccat ttgctactaa tacaaccatt acttctttag
     4501 ttgtaaaacc tatttttgtt actaaatgcc taatcaaccc cgtgtgagtc ttttcatcat
     4561 atatacttac cttataggcc cttatatatg tttttattat tttaacaatt ttatcattta
     4621 tctcatgttg tattacgcat ttttctgtcg atattacatc atgagtcttc tttttataga
     4681 agccaataat tggaatacca ttattctttt gtattggaaa ttgtgcttta tttctatatc
     4741 tatatggatt atccattcct atagtgtcat gaacttctac atcctctaac ttacctattc
     4801 tcgaaagtac ttgtttaact tcatttgttt tcatttcaag ttgtttatta taatctaagt
     4861 cttgtatctg acaccctcca caatccctaa gattctcact acacactctt ttcaccctga
     4921 atggagactt ttctattatc tcaacaatat ctcctacagc ataatttttc tttactttat
     4981 taatcctaac tttaacttta tcctgtatta atccgccctc tacaaaaact gtaataccat
     5041 tgtactttcc tactcctact ccgccttgac caatgtctac tatatctaca atatacatct
     5101 cgtttttcga aagcataaat caccctccaa tcaatctatt atatttaaat ctttacaaac
     5161 ttttttcttt aaatttatat taaaatattg ctattaatta aactatattt tttactaagc
     5221 tacaatattt tattttacca aaaaaaaagg agcttataaa gccccttagt aaataaattt
     5281 attatttttc ttataaaact ctagttgaac ctctatatac cacacctctt gatgcatcca
     5341 cagttacaac ttctccatct tttactagat ttgttatatc agttgcagac acaataactg
     5401 gtatatctaa atttatacct acaatagctg tatgtgatgt cattccacca ttctcagtta
     5461 ctacagctcc tgctttttct atataattgt tcatttcagc atcagtagca gtagaaacaa
     5521 gtatgtcgcc ttcattaaag tctacacaag catttccatt ctttattata cgaactttac
     5581 cttctaccgt ttgagtacct acacctatac cttgcacgat ttcttcgctt attacatgaa
     5641 cctttattaa attagtagtt ccacttactc ctactggtac tccagcagtt ataactacta
     5701 attccccatt atctatataa tcagcttgtc tagctgcctc aattgccttt tctataactt
     5761 catctgtatt tcctgcaaca gaagacttaa ctggatatac tccccatgta agagctaatt
     5821 tattcatagt cttttcatta tttgtagtag ctattattgg agattttggt ctaaatttag
     5881 ataccattct agcagtatat cctgaagaag tagatgttat tatagctgat gcatttaaat
     5941 ctactgctgt tgtacaagtt gcatggctta ttgcatctgt tacagtaaca ttgttagtac
     6001 cattttcctt taataatcta tcataatcta aagtctcttc tgttcttttt gctattgtag
     6061 ccatcatttt tactgcctct acaggatatt ttccagcagc agtttctcca gataacatta
     6121 tcgcatctgt tccatcatat atagcattgg caacgtctgt aacttctgct cttgttggtc
     6181 ttggatttct tatcatagaa tcaagcattt gagtggcagt aacaactggc tttgctaatt
     6241 cattacattt ttttatcatc attttttgaa ctattggcat ctcttcagtt ggtatctcaa
     6301 cacctaagtc acctctagcc accattatac catcagaaac ttttaatatt tcatctaggt
     6361 tctctacacc ttcttggttt tctattttag atattatttg tatatcagtt gcattattgt
     6421 tctctaatac ttctcttatt gctagtacat cagatgcctt tcttacaaaa gaagcagcta
     6481 tataatctat tccttgactt attccaaact ctatatcact tatatcttta ggagttattg
     6541 ctggtaaatt tatcttaaca ccaggtacat ttactccttt atgattttta actattcctg
     6601 aattttcaac aacacaaact atatcttctc catttatttc ttttactctt aagccaacta
     6661 aaccatcatc tattagtata gaatctcctg atttaacgtc ctcagcaaga cctttatagc
     6721 ttactgtaca catttcttta gtccccataa tatctttcat agttatagtg aacttttgcc
     6781 cttcttctaa aaatacctct gggtcttcaa agttacctgt tctaatttct ggacctttag
     6841 tatctaataa tatagcaact ggcttattta atttttctct aactttcttt gccatatcaa
     6901 ttctttcttt atgttcttca tgcgaaccgt gagaaaagtt aaatctacac acatttagac
     6961 cattttgcat aagttgagtt aaaacttcct cactttgtga tgctggacct agtgtacaaa
     7021 caatttttgt cttctttaca ttatttaaca tatttgctcc tcctgagata ttattccaca
     7081 gatttatttt taatactaaa acttatatag ataatatttt tgccatctca taagcttctt
     7141 tatcaaatac tttcttttga gctaaagctt cacttatttc taaatcaatt attttgtttt
     7201 cttttattcc tacaactcta gctgattttc catctaataa taattctact gctcttactc
     7261 caagtctact tgctagtatt ctatcagata cagttgggct tcctcctctt tggacatgcc
     7321 ccaatacagt gactcttaaa tctgctcctg actctttttt aagttccttt tctaaatcac
     7381 tagcacttcc gactccttct gctaaaacga ttatactatg tctcttacct cttttttgag
     7441 tagtctttaa tcttagagca acttcatcta ctgtaatttc tacttctggt actattatag
     7501 tttccgctcc tcctgcaaga cctgcatata aggctaaatc tccacagtgt cttcccataa
     7561 cttctactat gttaactctt tcatgagatg atgatgtatc tcttatctta cctatagcat
     7621 ctataatagt attcattgca gtatcaaatc ctatagtata atctgtatat gctaaatcgt
     7681 tatctatagt tcctggtatg cctatagctg ggaatcctaa gtcactaagt ttttgggctc
     7741 ctgcaaatga accatctcca ccaattacaa ctaagcaatc aattttatac tttttaagaa
     7801 tttttactgc ttttaatcta ccttcttctg ttttaaattc ttcacatctg gaagatttta
     7861 atatagttcc tcccctgtgt ataatatctc caacagaaga taagttcatt tcagttaaat
     7921 cttcttctag taatccctta tatcctctat tgattccata tactttgcat ccataatata
     7981 ttgctgatct tacaaccgct ctaatcgcag cattcattcc tggagcatct cctccacttg
     8041 ttagtaatcc tatagttttc attttttacc tccttggatt ttatgtcaat tttttattat
     8101 aatcattgtt attgtattct aatggacttt ttttgtccct atatcacttt ttaatcccat
     8161 caagactaaa aaaattaaat gtccttaaat gtccattttg tgatattata tcacaaaacg
     8221 gacaatattt ttcatattat tataatatat ttagattttt atataaaaaa tcaagctttt
     8281 acttttatgt tatctttagg aagtaactct tctaagttat ttataaattc atcacatata
     8341 caagtcaatg ccccggtcat tttatatgct ttacgtttac catttatatt ttcatccata
     8401 gggtacaagt atatactgtc attacctgga tattgtttgg ctatttctac aatattatta
     8461 gttgtatcag tatcagacat actatctatt ttcaaataca attttttacc actttctggc
     8521 ttaatatttt ctacatttct agttcttcct gaattgtagt ttctatctgc aaagtcagta
     8581 tcatcattta tatcttttat ctctctagct ataagttttg cattttcgcc ttcttttata
     8641 cttaatgttc cttttacata tattatatta tcttcattca aaatgacatt atacttttgt
     8701 aataattgag gaaaaactat tatttctata gcaccataca aatcttctaa ttcaataaat
     8761 gccataattt catttcgttt tgttgtttta atagttttag ttacaatcat tccacccatt
     8821 ataacatctg tttcattcat ttgtaggtat gactcttctt cctcttttaa tgaatttaat
     8881 tttccattat ccatagatgt tttttcttgt agttcttttt caaattgtga taaaggatgt
     8941 ccacttacat acattcccaa gacttctttt tcaaggttaa gtctctctct ttcttcgtac
     9001 tcttgccttt taggcaaact gtatatttgt tgaaaatcac tatcttcctc actatctcca
     9061 aaagcatcaa ataaagaaat ttgaccttga acatttttct ttctatccat agatacactt
     9121 tctaataaac tttcataacc agccatcaga ctagctctat tttcacttat attatcaaaa
     9181 gctccacatt ttattagact ttctattact ctcttatttg tatctttttg gtctaatctt
     9241 ttgactaaat ctactaaatc tacaaataat ccattagatt ctctttcagc gattatattg
     9301 tttattatat ttacaccaac attttttaca gctgctagac caaatcttat attgtcgcct
     9361 tcaactgaaa actttgaaaa acttttgttt atatctggag gtaatacatc tatttctagt
     9421 gctttacatt ctcttatata ctcaactacc ttatcagtat ttcccattac actggttatc
     9481 aatgctgcca taaattcaac tggataatat gtttttagat aagctgtctc atatgctaaa
     9541 accccatatg cagctgcatg tgatttatta aatgcatatc tagcgaagtc tatcatgtca
     9601 tcaaatattt tattagctat ttcctcttct acaccatttc tgatacaccc tgcaatttct
     9661 atattaccat cttcatcaaa tttaccatga ataaaatatt gtctttcttc ttccatcacg
     9721 tccatctttt tcttactcat ggctcttcta actaggtcac ttcgtccata actataacca
     9781 cctaaatctc taacgacctg cataacctgc tcttgatata ccaaacaacc atatgtaact
     9841 tccattatag gctttaattt ttcatgtaga tatgttacat cttttgggtt gcttttattt
     9901 tttatatatg caggtataga atccattgga cctggtctaa atagggatat tcccgctaca
     9961 atatcttcaa aattgtctgg ttttagctgt ttcataaaac ttctcatgcc agcactctcc
    10021 aattgaaaca cccctagtgt atttcctgat gaaagcattt catatacttt cgggtcgtca
    10081 taatccatct ttgaaaagtc tattttttct gtgtagtttt ttataactct atttttttct
    10141 attaaatcaa gagtatctct tataactgta agagttctta gcccaagaaa atccatcttt
    10201 aaaagcccaa gttcttcaag tgttgtcata gtaaactgtg ttgtgattgc atcttgatgt
    10261 ttgtacaaag gtacatattc atctacggga ttttttgata taacaactcc tgctgcatga
    10321 gtagaagcat gtcttagcat tccttctatc tgttttgata tatttattat ttcttttgtt
    10381 tccgggtctt ggtcatacaa ttctttaaga ttaggatttg tatctagggc cttatctatt
    10441 gtcattccta aagcaaatgg tatttccttg gctaccttgt caactttatt gtagcctata
    10501 tccaataccc ttccaacatc tcttattgca gcttttgcac ccattgtacc aaaagttatt
    10561 atctgggcta catggtcatc accatatttt ctctttacat aatctataac ttcttctctt
    10621 ctctcataac aaaaatctat atctatatct ggcatggata tacgttctgg atttaaaaaa
    10681 cgctcaaata atagagagta ctttattggg tctatgtcag ttattttaag tgtatatgct
    10741 actatagaac cagccgcact gcctctacct ggtcctacta taatattatt ttctttagaa
    10801 aaatttataa aatcccaaac aattaaaaaa tactctacat aacccatttt ttcaattaca
    10861 tctaattcat aatttaatct ctccagtatc tcattgctag gattatcata tctctctttt
    10921 aatccattaa aacacaactc ccttaaataa gtttctggtg tatatccttc tggaacatca
    10981 tacttaggaa gatgtatagt attaaaatca aactccacat tacacatatc agctattttc
    11041 acagtattgt caatagcctc taatgcatat ggaaataatt cttccatttc ttctcttgat
    11101 tttaaataaa actcatcact accaaatctc attctatttg ggtcatttaa tgtttttccc
    11161 atttgaatac acataagaac atcatgtatt ttcgaatctt ctttatttac atagtgaaca
    11221 tcattagtag caactagtgg tataccagtc tcttttgata attttactaa accagagttt
    11281 acttcttttt gctcaggtaa attgtgatct tgaatctcca aaaagaaatt ttcttctcca
    11341 aatatgtctc tgtagtcaag agcaaattgt tttgcttttt cataatttct attcattaaa
    11401 gcacgtgcta catctcctgc aaggcatgca gaaagtgcta taatcccttt gttatgcttt
    11461 ttaagttctt ccatgtcaac tctaggctta tagtaaaaac cttctacgta tgaagttgaa
    11521 actattttta ttaaattttt atatccttcc atattcttag ctaacagaac taaatgtcct
    11581 tgatatttgt catagtttgg gtctttatct ctcaatccac gtgcagctgt atagacttcg
    11641 caccctataa ttggctttat tccttctttt atagctgttt tgtagaaatc tataacacca
    11701 aacatacaac catggtcagt tatagctatt gagctcatgt ttagttcctt agcccttttt
    11761 ataagttttt tcaccctcga aaacccatca agtaaactat actcagtatg tacatgaaga
    11821 tgagcaaaat ctttgttcat taaatcacct cctgctttat aattttaatt ttaccacaaa
    11881 tatatgtcct aaaacaaaaa cagagacttt tatctcaaaa taggaattaa cttcaacgta
    11941 taccattata tgttataaat taatgcttat tctgagattg tcccctcaat ttattgctat
    12001 gatttttttt tcaaatctgt tgcaatttct tctatttttc taagtctatg attgactcca
    12061 gattttccta ttggtggttc taacatctct ccaagttctt tgagagtcat atcctcatac
    12121 tcgattctaa tcttagctat ctcttgtaaa ttttctggca aactgctaat tcctatagtc
    12181 tcttgtatga gcttaatatt ttctacttgt cttactgctg catttactgt tttagaaagg
    12241 ttagctgtct cacaatttac tatcctgttt acattatttc tcatttcttt tactatttta
    12301 gtattttgaa gacttaaaag agcgtggtgt cctcctataa tactcaacaa atctgatatt
    12361 tgttcactct ctttgatata aacaacgtga ttattttttc tagccacaat tttactatta
    12421 aaacctaaag agtttataag ttcttttaga gaatctgcaa actcctcatt attagttaca
    12481 aattccatat gatagttctt ttctgggtcg cttatagaac ctccaccaag aaaagctcct
    12541 cttatgaaag ctctcttaca tccttcatgc ttaattaagt tctctgaaat tttgtttata
    12601 gtaaaaaatc cttctttatc ttcaagtata cctaactttt ttaataacat ctctgaaccc
    12661 atttcgcttg ttaccattaa tacataactg ttatttctct ttagcatttg attcttattt
    12721 actgagattg tagtattaat attaaaattc ttttttaata atttaaatac tttacgggct
    12781 attgaattta actctgttgt tatctttaga tttagcttct tatatccaac aatttgtata
    12841 cttccccctg atttaactag agctgacaat tcagctatat tacaacattc attcccagat
    12901 ataactcttg ctagttcatt tttggtttca gttgaaaaag acatatctat cacctattaa
    12961 ctaatttttc tttaaccttt tttttatttc ttgtaaggca acctttatta tctccttttc
    13021 atcatcatac ctagctaagt ctactactct atctaggtgg ataaatttag catcaataaa
    13081 gccttcctct ttttgtggaa tagtatccat attctttgct tgcatcaaat accaaaaaac
    13141 tgttttatga actgctctat tttcatccca gttttctttg aatgtatagt gtatttcacc
    13201 taaatatttc aatatatctg cttttactcc agtttcttca cttacttcac gtaatgctgc
    13261 ctcttggtta ttttcccctt cttctacttt tcccttgggt aacacccaat ctccattgaa
    13321 cttccttagt aaaagaatcg tattgccaaa caggactaca ccaccagcac taacctcttc
    13381 tctcatcgat gttcactcct taaaactaac ataatgataa ggatttctac acaatttttt
    13441 aaaatccttt tttactaact tttgttgtaa ttatgattta gggctaactc aataactatg
    13501 ttagatatat actttgcatc atgtcttata taattatttt ttatttcaat taaattcttc
    13561 tctacagttt ttatacccat ctcttttaat ttatcttttt gctttttatc taacaagact
    13621 tgctctgctc catcttgttt atataagtca agcatttctt ctggcaatat ctcattattt
    13681 gcgattacat aatctattaa attctcatca gtgtgtttta ctatagcatt aacatgctct
    13741 aatacattgt acccttctgt ctcacctggt tgagtcatta tatttgctat atatactttt
    13801 ggagctacag acgatttaat agcgtctaca atcccctcta caagtaaatt gggtattata
    13861 cttgtatata aacttccagg acccataatt ataatgtcag catcataaat agatgcaata
    13921 acatccttta atggttttac atcttttgga tttaaaaaaa ttttatcaat agagcttttt
    13981 tgaatttttg actcttcagg tatactagat tctccattta ttatattgcc attttctaat
    14041 ttggcaacta aatttacatc ttccaaagtt actggtaaaa ctcttcctgt tatagcaaaa
    14101 atttcactta atttatatac agctttttca aagtttccat acaacccatt catagcagcc
    14161 aaaaacaaat ttccaaaact ctgacctttt aaaagccctt ctgtaaacct atattgcata
    14221 acttcattca ttgttggctc tatatttgca agtgctaata aacagtttct tatgtctccc
    14281 ggtgggagca ttcctaagtc ttctctcaat acacctgaac ctccaccatc atcagcaaca
    14341 gttacaattg cagttatatt ttgcgtagtg tgtttaaggc ctcttaaaaa taccgattga
    14401 ccagtacctc cacctatcac aaccacattt ggttctctat tttcaacaat agacctttga
    14461 aatagtttta ctttttcatt ttttgctttt ttatatataa ataacgatac aattaatgca
    14521 atccaaccta aaattcctac aataataagt aatttagcca tgtttgcctc cattatcgca
    14581 acatagagtc tctatgtttc tttacaactc tatatccctt attagataaa tcctccgcta
    14641 taagatttgt tatagtaact gacctatgtc ttccacctgt gcatccaaca ccaattacta
    14701 gatgttgttt tccttcctct atatattgag gtactaaaaa atgaatcata tctaaaagtt
    14761 tcacataaaa ttcttcactg attttagaat tcataacata atctctaact tctttatcat
    14821 caccagtttt agctcttaac tcttcaacat aatagggatt tggaagaaat cttacatcaa
    14881 atactaaatc tgcatcagca agtataccat gtttaaatcc aaaagatact acagaaatag
    14941 ttaggtttgg attatcttca ccagaagaat atattttctt tatttcttcc ttaaggtctt
    15001 taggtttcat gttagttgta tcaattatac atgtagataa ctcctttaaa ggttccatta
    15061 tctttctttc catttttata ccttctggaa tctgcatatc ttttgccaat ggatgatttc
    15121 ttcttgtcat tttatatctc tttaacaata catcatcatt acaatccaaa tataccattt
    15181 catattcata attttctttt tctaaataat ttaagctttc atgaagcgct tcaaaaaact
    15241 ttctccctct tatatctatc cctagagcaa ctttatcaat acttgaattt ggttgataac
    15301 ataattctgc aaatttagtt atcaaagcag gaggtagatt atctacacaa taaaatccca
    15361 tatcctctaa agctctcatt gtctcacttt ttccagatcc tgaaagacct gtaactataa
    15421 caaatttcat tgctaactcc tcccttttat cttatgttta ttatattata atgttttcta
    15481 ctaacgatat atccagatta gagtcagata tagtcttcat agctagttca aaatcaccaa
    15541 ctctttctgg acaatgtgca tctgagccta ttataaattt attttctagc ccttttattt
    15601 tatttaattg atttacattc aaaaaagaat ggctactatt tatctcaagt ctagtatttg
    15661 tcttttttgc tgtctttgct acttcttcta tatacacatc gcctttatct cctggatgag
    15721 taattataaa aatatcatta ttacttatcg catttattac agcttttgta ttatattctt
    15781 ttgctttttc agttttaaaa atatagttat tacaatgatt taataagctt cttaatgatg
    15841 ttggagtaga accaaagtga tatccagcca taatataatc aaaatctcta ataaatttat
    15901 catccatatc tatatttcct ttatcatcta atatgttaca ctccatacct aaaagtatat
    15961 ttatatcagt gtacttatca tttaaataat ctacttcttc tctcattttg agaatatctt
    16021 ttttctttac accatatgca atatgtttat aactatggtc agatattcct attgttttta
    16081 ttcctttaga aatggctacc tttacattat cctcaatagt ccctttgcca tgactatata
    16141 atgtatgtgt atgataatca gccagtattt tcatttgtta atcctctcca agtattttga
    16201 cttcttcttc caacataacc ccaaacttgg catatacagc actttttata acatatatta
    16261 aatccaaaat atctttagca cttgcttctc cttgattgac tacaaatcca caatgcttct
    16321 cagatacttg tgctcctctt aaagtaagac ctctcaatcc agtttcttct attaatttac
    16381 ctgcaaaata tcctgttggt ctcttaaatg tacttcctgc actagcaaaa tttaatggct
    16441 gtttagttat tcttctcgtc gctaaatcat ccattaaact ttttatttca tcataatttc
    16501 cttcttgtaa ctctaattct gctgataaag ctatatatcc gtttttcgat attatacttt
    16561 ttctataccc aaattccatc tgttcatttg ataattcaaa tatattgcct tccatatcca
    16621 tcagtcttac tgacttcact atgtccttca tttcaccacc atatgctcca gcattcatgg
    16681 ctaatgctcc tcccaatgtg ccaggtattc ctgatgcaaa ctcaaaccct tttaattctt
    16741 gcttttggag agctttccct aaaactgata ataaagctcc tgactgagca gtcatcctag
    16801 tatcatttat ctcataagaa ttgaaattat cagctaattc tattaccact cctcttattc
    16861 caccatcttt aattaaaatg tttgaaccat ttccaattat taaatacgga atagattctt
    16921 tttttaccaa cttaagtaca ttttttaatt gttcttcagt tctaggtcta actaatatat
    16981 ctgctggtcc tcctacccta aatgaaatat gttttttcat aggttcatcg acttttatat
    17041 cctctttact taatatattt aataaattta tatatatatc ttgattattc attgtatttc
    17101 ctcccaaatt atactgaact ttagctgtca ttattattta aattacatta gtatatagta
    17161 ttaactatat tcaataatat atgattttgc ttatcatata gattttatat tttaagcttc
    17221 ttaattacaa actatattca ataaatatat aataaagtaa aaaaaaaaaa ataacaacat
    17281 ataaaagaat ataaataatt taaaaaaagc atcaatatca ctgatatcaa tgctttaaaa
    17341 ggcaatttaa ttcgtattat ttatctaact atttttgaca tagcaaagat aataaatccc
    17401 tccaactact atggaacctc caacgatatt tccaagcgtt acaaatacca aattagttat
    17461 aaattgaacc atagttatat ttgctcctaa tgccattccc attggtataa aaaacatgtt
    17521 tgcaacacta tgttggaatc cacataatac aaatagcatt attactgtcc aacatgaagc
    17581 caattttgac attatatctt gagatgctgt agccatccat acagctaaaa cgactagaat
    17641 attacaaagt attgctttta aaaacattga tgctatagtt gaattaacct tagcttctgc
    17701 cacagctata gcttttgtag ctgcatctcc tgtcaatgta gaagaataaa acacaagtgc
    17761 aactagcaaa attgaaccta ctaaatttgc aaaataaacc agtccccagt ttcttaacat
    17821 ttttcctaat gttatttttt tgtccataag tgcaatagcc attaatgtgt ttccagtgaa
    17881 taattctgct cctgccacta ctacaagcat aagacctact ggaaagacca tagcacttaa
    17941 aaagctagct acccctgggt ctaccttgcc aaaagtttga ctaactatca tactccccaa
    18001 tgccccaaaa cctataaatg ctcctccaaa taaacctaat agaattgcat tttgtgtcga
    18061 aatatttgct tttttaatgc ctgcacttat agttgcttgt gcagtttccc caggtgtcaa
    18121 gaatccttta ctcataaatc cttccccctt aaaaattata ctttcccttg tctttttatg
    18181 gcaataatta tataataaca atatgatata taataa
//
LOCUS       DAEOTL010000085        17733 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEOTL010000085 DAEOTL010000000
VERSION     DAEOTL010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17733
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.085"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(59..1663)
                     /locus_tag="KRH82_003148"
     CDS             complement(59..1663)
                     /locus_tag="KRH82_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656413.1"
                     /translation="MKEKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            2049..2975
                     /locus_tag="KRH82_003149"
     CDS             2049..2975
                     /locus_tag="KRH82_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBG8656414.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(3095..4093)
                     /locus_tag="KRH82_003150"
     CDS             complement(3095..4093)
                     /locus_tag="KRH82_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBG8656415.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            4197..4634
                     /locus_tag="KRH82_003151"
     CDS             4197..4634
                     /locus_tag="KRH82_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656416.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            4720..5307
                     /locus_tag="KRH82_003152"
     CDS             4720..5307
                     /locus_tag="KRH82_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBG8656417.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(5607..6227)
                     /locus_tag="KRH82_003153"
     CDS             complement(5607..6227)
                     /locus_tag="KRH82_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBG8656418.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(6235..7002)
                     /locus_tag="KRH82_003154"
     CDS             complement(6235..7002)
                     /locus_tag="KRH82_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBG8656419.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVVNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(7043..7864)
                     /locus_tag="KRH82_003155"
     CDS             complement(7043..7864)
                     /locus_tag="KRH82_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656420.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(8223..10133)
                     /gene="phnW"
                     /locus_tag="KRH82_003156"
     CDS             complement(8223..10133)
                     /gene="phnW"
                     /locus_tag="KRH82_003156"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBG8656421.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     DYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDIEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(10412..11197)
                     /locus_tag="KRH82_003157"
     CDS             complement(10412..11197)
                     /locus_tag="KRH82_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBG8656422.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPMSIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(11414..11644)
                     /gene="dltC"
                     /locus_tag="KRH82_003158"
     CDS             complement(11414..11644)
                     /gene="dltC"
                     /locus_tag="KRH82_003158"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBG8656423.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(11663..12811)
                     /gene="dltB"
                     /locus_tag="KRH82_003159"
     CDS             complement(11663..12811)
                     /gene="dltB"
                     /locus_tag="KRH82_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBG8656424.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPSVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEIIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(12811..14325)
                     /locus_tag="KRH82_003160"
     CDS             complement(12811..14325)
                     /locus_tag="KRH82_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBG8656425.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYRELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGRIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(14446..15636)
                     /gene="dltD"
                     /locus_tag="KRH82_003161"
     CDS             complement(14446..15636)
                     /gene="dltD"
                     /locus_tag="KRH82_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBG8656426.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(15924..16943)
                     /locus_tag="KRH82_003162"
     CDS             complement(15924..16943)
                     /locus_tag="KRH82_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBG8656427.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(17119..17658)
                     /locus_tag="KRH82_003163"
     CDS             complement(17119..17658)
                     /locus_tag="KRH82_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBG8656428.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
BASE COUNT         5820 a         3068 c         1838 g         7007 t
ORIGIN      
        1 ctacctaact tattatataa aactattttt tatagattat aaaatatcta actttcatct
       61 acttcaaaga atacaatact tctccttctc ttatagtctg caatacttta atatctttta
      121 ttttcatagg gtcgattgta agtgggtttt catctaatat tatcaaatta gctaatttcc
      181 cttctttaat tgaacctttt ttatcttctt caaaatattg atatgctgca tttatagtaa
      241 caccctttaa agcatctaat gggcttatct tttcattttc tcctatttgt ataccttttt
      301 ttgtaattct attgacagca caccatactg tttccagcat attaggtgct attactggtg
      361 tatcctgatg aagagtgtaa attaatccct tttctatagt tgttttaagt gggctaatct
      421 taaacgctct atcttctcca aggtttttga tatgaatatc accccaataa tatgtgtgag
      481 ctacaaagta tgaaggtatc atatttatta ctttcatatc atcaatctgg tctgctctta
      541 ctgtttgagc atgtatcata actggtctta tattattttc actactttgc tcttttaagt
      601 ttaaaacttt ctcaaacgca tctatcaact ggtctgctgc tgcatctcca ttacaatgag
      661 ttaatagttg catcttttct tttagtgaaa tatctataaa cttttctact tcttcatctt
      721 tgtatatagg atatccacaa taaccatcat ctgaattttc atatggtcta ctcaaccatg
      781 ctgtcttacc ttgtggagaa ccatctaaga aaatcttata acctcctatt ttaaatctat
      841 ttatatattt ttttataaac tccctattat tatctactac agacttactt tttttcaaat
      901 ttacatatcc tacaacatcc atttttaatt tattttgatt tgccattgct tttaaaatgt
      961 taaattgatt ttcttccatt aaaccttctt gtgctgttgt aataccatag cttagatata
     1021 tgttctgtgc tttttcaatt gaattaaaaa tctcatttga tgatggttgt tttattttag
     1081 atgctacatt aaaaaatgca ttttcttcta aatatccatt tggttcttca ctgccttcta
     1141 ctctacctat atgtccacct tctgggtcac gtgtttcatt ggtaacacca agctgtttta
     1201 accccaatgt atttgcaact cccatatgac cagaagcatg tgaaattagt attggatttt
     1261 ctgaagatgc actatcgagt acactcttat ctggatgctt attttcttct aaaaaattat
     1321 tatcatatga aaatccaatt atccagtctc ctttttttat attattcgac tctttgaaat
     1381 cctgtatttt ttttactatg tctttaaaac tggttgcatc ttctaaagga actagcttta
     1441 gagtagtagc aaaagctatc aagtgactat gtgaatctat aaaagatggc atcaatgtct
     1501 taccttgtaa atctataatt tctgtatctt tatttttcaa agcaaatact tcttcttttg
     1561 ttcctatctt ttttattatt ttgtctttta taagaatagc atctccacat attgaatctt
     1621 ccattgtgat gatatttcca ttgtaataaa ttttttcttt cataaaattc tccttacgtt
     1681 gtctacttta ataaattttt ttcattattt tctgcttaat tatattatct tctttataaa
     1741 ctttttcttt agagtttaat catataaaag ttttattttt aattattgtt tgccaagaag
     1801 taaatactat tcattgtaaa taagacaaat taataggctt tatactaatt gaaaaaatat
     1861 tataagttgt taaatttaaa tatctaaact caattatatc tgtacaattg taatttttta
     1921 aatcatgatg tattatttta aatatacagt tacattatta ttcacaatat aagtatctta
     1981 gttctcaaat aacatctcat gtaatctatt caatgcaaaa aatttaaata ttttttagga
     2041 ggttttttat gagcaaggaa aataaaaatg taagaattgc tgttgtccag gcgtcaccag
     2101 tcataatgga tttagaaaaa actgttgaaa aagcattagg attaattaaa gaagctggta
     2161 gaaaaggggc aaatatcgta gttttccctg aagcattcat acctgcatat ccaagaggtc
     2221 tttcatttgg atttgttgtt ggaagtagaa caatggaagg tagagaagat tggaaaagat
     2281 actatgataa ttctgtacca gttcctagtg ctacaacaga tttattagga aaagcagcac
     2341 aagaagcagg agtatatcta tcaatgggta taacagaaag agatggtaat gatataaatt
     2401 gtacccttta ttgcacaaac ttatttttct ctccagaagg taagctaatt ggtaaacaca
     2461 gaaaacttaa acctacagga acagaaagat gtatttgggg agaaggagat ggaagtactc
     2521 ttacagtagt tgatactcca tatggaaaaa tgggttcgtt gatttgttgg gaaaattata
     2581 tgccattagc tagaacagct ctttatgcta agggtgtaaa actttacata gcccctactg
     2641 cagattcaag agaagagtgg caagcaacta tgaagcatat tgctttagaa ggaagatgtt
     2701 ttgtaattgg atgcaatcaa tatgttgaaa aaaatatgta tccaactgac cttaactact
     2761 ataaagagct agatgcagaa ccagaaatta tgtgtccagg aggaagttgt atagttgacc
     2821 cttttggaaa atatgtagca ggtcctattt tcaataaaga agaaatgcta atagctgatt
     2881 tagacctaga aaaaatagta cttagtagac tagattttga ttcagaaggt cactattcaa
     2941 gaccagatgt atttgaatta attgttcatg aataatcttt ttacacaaac atctacataa
     3001 atctttttac ataaaaaaat gagatactca caagtaaatt tcaagtatct catttttgct
     3061 taaaacctat aatcctaatt ataaatttat tcacctatat tttttctaaa tcaactactg
     3121 ttcttccaac atgttttcct gccattattg aatctatact atcatttaac tcttccaatg
     3181 atactacatt taccatatca tctaaatcat ctaatttcca ttcatttgat aataaatccc
     3241 atatttttaa tcttaagttc attgggcaat ccacagaatc tataccatat aaagtaattc
     3301 cctttaatat aaatggatat actgaacttg taaaatcaac tcctcctgca ttaccacaag
     3361 ttgttactgc tccacaataa ttagttgtct ttattgctgt tgctagagta tttcctccta
     3421 ctgtatctat tactccagcc catcttggtc taagcagagg tcttcctgag ttatcatcca
     3481 cttctgacct atgtataaca tctttaacac ctaagtttag taatacttct ttttgttctt
     3541 ctaattttcc tgttgaaact acaactgaat aacctaattt aatcaatatt ttagttgcaa
     3601 ttacagcaac tcctccagta ccaccagtga ctaatacatc tcccatattc ttgtctacag
     3661 aatctataaa tttatacaca gataaagctg ctgtaaaccc tgctgtacca taatccattg
     3721 cttcttttag tgaaagattt ttaggaagtt taactaccca actagaagga actcttatgt
     3781 attctgaaaa accaccagaa gtattcattc ccaagtcata acctgttact aaaacttctt
     3841 ctccaatttt aaaatcatca caactactag attctactat accagatgca tcaattcctg
     3901 gtgtatgagg atactttctc gtaacaccct tattaccatt tgcagaaagt gcatccttgt
     3961 aatttaaaga agaatatttt acttttatta gaacttcgcc ttctggcaat gtatctactt
     4021 ctctttcaac tatatttctt ctaaaatttc cttcttcttc tgtaatatat agtgatttaa
     4081 attttttatt cataaatttc ctcccaatac atttagtttt atgttaaact aattatagtt
     4141 tataaatagt tttatgtcaa actaatttaa atagattaaa gattggagaa taatttatgg
     4201 aagataaata tattgtacat ttcataagta aaacaaaggc tagtatgatt aaattcattg
     4261 aaaataaact cagtaaaaat ggtttaggtg agttaatacc tactcatgga aatattttaa
     4321 ctgcacttta tgaaaataat ggaatactta caatgaaaga aattgcagct aaaataggaa
     4381 aagataaatc cactgttaca gtgttggtta ataaacttat aaacctagga tatttagaaa
     4441 gacaaaaatg tacaaatgac aaacgtatca cgtatataaa gcttacaaaa aaggcactgc
     4501 ttatagaaga tacttttaat agcatctcaa cacaagttaa agagacagca taccataata
     4561 ttacagaaaa tgaaaaacaa gaatttctta gaattttaaa aaaaattaat gataatttta
     4621 aaaatgctga ctaaattgag cataattata tctcctattg gaataataaa taaaaagaat
     4681 caaatattgt aaaaatttat tatgatagag aggtagaata tgaatttaaa agatagtaaa
     4741 actaaagaaa atttattaag agcttttgca ggtgagagtc aagctagaaa tagatacaat
     4801 atttctgcat ctgtagcaaa aaaagaagga ttatatataa tagagtcttt atttaattac
     4861 actgctgacc aagaaaaatc acatgcaaaa caattctttt ctaaattaaa agaatttgct
     4921 ggtgaaaata taagtatatc aggagcatac cctgtagatt tatatgacaa gacagcacaa
     4981 caccttaaag ctgcacaaca taatgagctt caagagtggg atgatgtata taaaaacttt
     5041 ggaaaaacag cacgtgaaga aggatttgaa tctatagcta agttatttga aaatatagct
     5101 gaaatagaaa aagttcatgg tgatagattt ggtagatatg ctactgattt agaagaaggt
     5161 actttattca gaagaaatga agatatacaa tggatatgta cacattgtgg ccatatacat
     5221 ataggtaaag aagctccaaa agcttgtcct gtatgtcttc atccacaagg atatttctta
     5281 gattttaaaa actcattatt tgaataaatt aaggcaataa ttctatttaa acaatttact
     5341 atatttatat caagtatttt tataaatact gtattatctt aataacaata aaatgaacca
     5401 ttgatattac tataagtaga aaatgtagtt taaatacaat ttatagtaat tcatcatggt
     5461 tcattttatt atttactaat ccctataacc tacttaaatc tatctttaac ttttacacac
     5521 tcacataaaa tcttatcttt aaactaaata tttaaataaa gtgtatttta agtatattat
     5581 tataatacat tatataagat aatacactat gataacttta tacttatatc atttatttct
     5641 tttgtcaagt caatctcaat aatcttaact acatcttttt caaactttac ttttttataa
     5701 tccagacatc ctactacgaa tggaactcca aactttctaa acaaataaat ctttccactt
     5761 tcattgtata ttgatgtaaa attttcttct attatattca ctatcaattt taactcttca
     5821 aaagttatta tagatttaac taaaaacttc tctattatgc tcaatataag cagttctttt
     5881 ttacctatgc tttgctcttt tttatataaa ttttgaaata tttctttggt ataattacat
     5941 ataacttctt tactgagaat aaaatcaatg tcaaattctt tattaatatc ctttttcata
     6001 aacatatttg caatatcatc aagagaagtc tcctctttca tagacaatat taactctatt
     6061 ctttctagta ttttatctct tggaaagaaa gtctcttgac ctgtaaaagc tgattttttt
     6121 ataaaccatt cctctggtat tatgtttttt cttttccatc tatataattg accataagat
     6181 atattagttt tgctcaataa atctttctta gatattaatt cttccataac ttttctagcc
     6241 cacctttata ctgtttttta cagtagaatt atctgaaact gataaattat cactgtattc
     6301 aatatttaca acgtcacaat tatctactag agatatgctt ttgcctcgta tatcttttat
     6361 tgatgcatct tctaattcaa tagtatctcc ctctatcaaa ttacatttaa actttcctga
     6421 aaaaatatta atgattttaa ttaatgaaaa agcatctttg cttcttccta tttttatatt
     6481 agttgcccct atctctttac aataagaacc tcctcctgaa taaacatata tattttctcc
     6541 atttaaaaga ccatcacatt ttattgctcc atataccttt atatcttcac attctatatt
     6601 tgatttattt ctcatttcgc catagatttt tatatcttgt gcatacatat tttcatttac
     6661 acttaattgt cctcttattg taacattatt acatttaagt ttgccatcca ctttctgttg
     6721 agcagttata actaagtcat ctatttctgc atctccctct atattaagtt gaccattcac
     6781 tcttacacgc tctgctttaa gattgcctct tataatagtt tttccgttaa caacaaaatt
     6841 ttttatattg atgtcacctt caaattttgc atctccaagg acttttactt cgttactttt
     6901 aacatttcct tttgatttag agcttcccac gatttttata ttttcatact caccactact
     6961 tataaagcct tctccaagta tttttataga ccctttttcc atattattac ctcattttaa
     7021 attttatttt taaacctact tattacttat ccttctttaa ttttattttt tcacttatat
     7081 tctttatttc accaactatt gaatcttcat caatctctat actttcactg tactccaaac
     7141 tttctacata acatcccttg cctattttaa tattttttcc tcttacaact ttgacttcac
     7201 tattttctaa gcttatttca tctgcttcta taatatttgc aaacaattta ctttctgtat
     7261 actttctaat tgataataga cctaaactta ttaaatttga agacactttt tcaaagttga
     7321 tatgcttttt ttctagcata cgaaattttt tgcaataatc tccatgcccc ttttttatat
     7381 ttatactact tgctccaact tcattaaaat tagaagttcc atttaaacta atattaactt
     7441 cttcacaatt caaaaatcca ttacactcca agattccact taaattgata ttttcacaat
     7501 ctatattctc atttgctttt aaatatcctt ctccatgaat aatatccgat tttatacttc
     7561 cttctacatt aataattcca ctagtatcaa tttcaacaga attaatattt cctgtacatc
     7621 taagaagtcc cgatatctca acttttgatg ccagtatgtt tccttctact ttacttaaac
     7681 cagatgtaaa aaattcatta cattctgttg tcccaaaaac ttttgctgaa ccagaagaat
     7741 caaatttact acattttaca cttccttcta ttttgcctgt tcctgatata ttaacattat
     7801 caaaaattcc acctttacat tttccaacac catcaaatct tagtgaactt aattcttcat
     7861 tcataatgat atcctttctt taccgtattt tatctctaaa cctaatataa caaaacattg
     7921 ttacgttgtc aagtatgata ataatactta ataaagcaac tatcatttat tttctataaa
     7981 taggcataaa aataataggg aaattcttta tttaaactat aaatctaatt tcttagattg
     8041 tggtttaaat aaaatatatc cctattactc aatctttata tattcattgt ataaacttct
     8101 aaaatataaa tctttaaatt ctactgtcaa tactttttat acactgtttg tgctatcatc
     8161 tcacacacct aaaggagtgg gctttccaca ctattctgta acctacaaga cactatcttc
     8221 ttctatctat tgataaattt ttctattaca tcagctagtc tctccatatc agttggataa
     8281 acttcaccta tgctacctat tctaaatgta tctatatcag tcaatttacc tggatagata
     8341 acaaatccat tatcttttaa ataagtataa aattccataa attcaaactt tgcattttta
     8401 ggatataaga aagttgttat tacaggtgat tgagcattat cattcaccaa agtatcaaat
     8461 cctaaagatt ttaatcttga agctattgta aactgatttt ctttatatct agcatatctt
     8521 ttttcaacag aaccttcttc ttccaattct aataaagctt gataaaaagc tcttacaaca
     8581 tgtgtaggtg aggtaaatct ccatttacca ttatttttct ccatagtctc ccattgcgca
     8641 tacacatcaa gagataatga tttagctata cctttacatt tagataattt ctctttatta
     8701 gctattataa aaccaaatcc aggtactcct tgtatacatt tgttagaact actaactaaa
     8761 aaatctatat taaaatcttc aacatcaatc tcaattcccc caaaactact catagcatca
     8821 actatataaa ttttgttata ttcttttgca agtttcccta cctcttgtat aggatttaat
     8881 ctacctgtag tagtttcaca gtgaaccatt gatatatgtg ttatatcctt gttttctttt
     8941 aataaatttt ctactacatt taaatccact gcttctatat ctttaaaagt gcagtcaaca
     9001 aattctatgt taagataatt acatatatct ttcattctct ttccatatgc tccatttgca
     9061 attacaagaa gtttaccatc ttttgaaata gtacttccta ttatagcttc tactgaaaaa
     9121 gtcccacttc cttgcattaa tacacttgtg tatttatctg tattttgggt tgctagagat
     9181 actaatcttc ttctaacatc ttgtactagg ttattatatt caatatccca agtacaccaa
     9241 tcttttaaca tagatgctct tactgattta gtagtagata gtggtcctgg tgtaagtaat
     9301 atgtaatcat tttctggtac aaaatctgat ttaatagttt cattctctat ttttattagt
     9361 atatcttcta actcagccat agtttctatt acaaaatgtg cacctgcctc tttaaatttc
     9421 tttgaaacta tactcatctt agcttttaat tcttccttat ccatgttctc tacttcttct
     9481 tgtgtaagcc ctaactcact tgaacctttt attacagcaa cactccacat tcctgcattt
     9541 acgccttctt ttacatcact tattgtatct cctactttta ccatagaact cataggagac
     9601 acccctaaag cttcagcatt tttatagcac atccaaggat atggtcttcc ttgagatact
     9661 tctgatggtg ttacaagaaa atcgggtgag tatcctttct ttgctgcatt tggttcaact
     9721 atgttcatca tctctcttgt ataacccgtt gtagaaccta tttttaatcc attttttctc
     9781 aacttttcaa tagtttcaac aacatgagga attggagtcg tataatcttc taatgtctca
     9841 aataacattg gctcaaattc agcataaagt tcatttacat catcttcagt tggcacttta
     9901 ccaaatttat ctgaccaaat attctttatt ctatccattt cacacatttc tcttatatgg
     9961 tctattttta attttcccat aggttttctt gcttcttcca ttgttacatc tatacctctt
    10021 cttttaaata tctctataaa tacattaaga ggtgcaaaac atccataatc tactgttgtt
    10081 ccagcccaat cgaatactac tgcttttatt ttttctccat atatcttttt catatttata
    10141 gcctccatag attcttttta gaatttttgt gtttttaatt gtttttactt ttaaagtata
    10201 actttcatat gttaattata catcatattt aggttaaata tatattaaat ttctgttttt
    10261 agttgtattt agttgttttt attttgtatc atattcccat aaaatcctaa gttacaatct
    10321 aaaatttact ttctaatctt aatctatgaa ctgactatat tttatgaatt tagttgtatt
    10381 gagcatagtt gtattatata aaactaaggg tttattttgc ttctatccat gttatattta
    10441 tctcatttaa cttatccttc cattcattcg gaggttctac atcacaaata acaaaatcta
    10501 attcctctaa atctgctatc ttatacatac tagcaattcc tattttagaa ctatcacata
    10561 atacaaaact ttcctttgaa ttttttatat attcttttga caacaatgcc ttattttggt
    10621 ctatactact aattccaaaa ctatcaagta taccttcact agatataaaa gctttatcta
    10681 cgtataagtt tttcatagta tctattgaca ttggacatgc tgtcctttgg tgttttaaat
    10741 ttacttttcc accaataaat ataacttctc catcaaacaa accttgattc tcataagaaa
    10801 tcaattttga tagaactgga taagagtttg taataatttt taaattgttt acagatatta
    10861 tataatctac aatctgcaaa ttggtagtac cttcatctat gataattgac tcattgtcat
    10921 ttacaaattt agctgcatat ttagcaatac tttgcttttt atctaggtta gtattgtttc
    10981 tctttatatg ttctggttca atcactccat aatttatttt tatagcacca ccatatacct
    11041 tttttaattt attttcattt tctaattctt ccaaatatct tcttattgtt tctgatgata
    11101 cttctaatct ttttactaat tctttagtgt ttaccttccc ttttgaatct aataatttaa
    11161 gtatttcttt ttttctatct atcgaattta aagacattca ttttcctcct aaatataata
    11221 tatttttctc ctataatatt acaatgatac ctaagattta tgaaatcata tttatgtatt
    11281 aaatttttta cttaattaaa gttattttca aaagactttg tattatcatt aaaaaagtcc
    11341 atcaaatatt agtatcagat ggactttgta aaattttatt ttataaatta atatttaaag
    11401 tctaactact aatttatttt cttgtctcca agaattttac taaattattt acagtagaca
    11461 tatcttttct ctctaaatca gttggttgaa gctctatccc taatctattt tcaatttcaa
    11521 gtaaaacttc aattatagct aatgagtcta aaagttccgt ctcaaataaa ttaaggtcta
    11581 aatcttctct tatctcatca gttcctaata catcttcaaa tatttctata actgtttctt
    11641 gcataaattt tcctccttaa aattaagcta aataacctga gaatatcagc aatccaaaac
    11701 acacaatatg gaatgtaatg aaaatctgca ctctctcgaa ccatttatct tttttatgtt
    11761 ttttataaaa tttagatttt cgctgatata tatcagttaa cacaagtgcc aatccttggt
    11821 atacaccata agcaacataa taccaagtta gaccatgcca aaatcccatt gttatcatgg
    11881 ttatcatctg agccacatga gcagcagtag tccttttctt aaatcttttc tttctcattg
    11941 atgacataac aaatctagaa aaaatataat ctccaaacca tcttgaaaga cttatatgcc
    12001 atcttgtcca gaactctttc atatctttgc tgataaatgg cttgtcaaag tttataggta
    12061 cttgtattcc aaatatgtac cctgtaccta tagcaaataa actatatccc gcaaaatcaa
    12121 agaacaggta taaactatat gcgtacatat aacttaaaat atttataaaa ctcatatctt
    12181 taggtattct tgatacccaa tatgtattta tcaaaaatgc tataacaaac ttataaccta
    12241 ctcccatgac aatatttttt attcctggca gtaagtattc ttctatatac tcttttctag
    12301 agatttgttt ttccaagtcc tgttcaaatc ttcttgacct atcaataggt ccagaactta
    12361 aagttggaaa aaataacata aaataaagca tctttgaaat tttaacttct tttatagctc
    12421 catcataaat ttcaataacc atttgtatag ttctgaaatt taagtatgat attccaataa
    12481 atccaattat tccaaaagaa gtaactggag atattttatt tattattatt gggagcattg
    12541 atgcaaacaa gaatccccaa tatatgtatt tatttttagt ttttcttctt acatattcat
    12601 atcctttaac tattattatt tcaagaataa taaatattac caagtacttt agttggacat
    12661 caattcctac tattaagaat atcataaaca aacttgccaa cataccataa tactttatat
    12721 tcttgcccat tagacctaaa attactgatg gtattgatgt taataataat atataaagat
    12781 aaaaataatc tccatattgt gaaaaaatca ttaaatttcc tccataagtt tctttctgtc
    12841 tattttacca ttgatatttg ttggaaactc agagattatt gaaatatttc ttggaatcat
    12901 atatgaaggt atatactttc caagttcctt ttttattatc ctcccatttt taatattact
    12961 taaatcattc ttttcattta actcaacaat accttttaag taagcaattt tttcgtcctt
    13021 atatactggt aaaactactg cattttttac attatgtact tttctcaaat tattttctat
    13081 atcttctatt tcaattctaa atccatttaa tttaatctga aaatcttttc ttccacaata
    13141 atatatattt ccatctaaaa gatatcccat atctccagtt ttataagctc tccactttac
    13201 accatctatt tcatcataga aaaatacttc atcagtcttt tctttattat tgaagtaacc
    13261 tttagaaact gatggtccaa ttattataat ttcacccttt tcattttctt taagctcatt
    13321 tccatcttca tcaagtattt ttattttaca atttgacata gggtatccaa ctggaagact
    13381 tttttcatca tctatagcct tttgagtcat atcatttaca cttacaccaa cagtagcctc
    13441 ggttggtcca tatccattga taattcttgt gtttggaaat ctactcataa gttctttagt
    13501 aagatttttt gaaagtgctt ctcctatgaa tatcattgac tcaaggttag gaagcatttt
    13561 actattaaac tctttttcag ttatacatac tcctgcaaaa gaaggagttg acacccatac
    13621 agctatatct gagatactaa attgtctaaa tagttctcta tagtctgcta atacatcttt
    13681 tgatattgaa aataatgtag ctccatggat aagaccaggg tatattgttg taactgaaag
    13741 gtcaaaagaa tatgctggtt ggttcattat tactttttca cttccatcta tgtttagata
    13801 tgggcttatc caatctgaaa agctatctaa attgtttgaa cttatttgaa ccccttttgg
    13861 ctttcctgta cttcctgaag taaatagtat atatgcattt tcatcatctt ttacccagtt
    13921 ttctttatct aatgattttc cctgatattc atttattata taatttaatt tatccatatc
    13981 aattacattg atatctccaa aatttctttc atcactaaag ttaaataata cctttggttt
    14041 tatctcttta gtgacttcaa aaactctatc aattggaaaa ctaatatcaa gaggcacata
    14101 cgctctgcct gattttaaag ctcctatcat acatgccatt atcatgtttt ctttatttcc
    14161 ataaattact ataggagtat cttcttcttt gtatacatcc tttagaaata ctgatatagc
    14221 atctgaatat tcatttaaat ctttataaga aagtttatct ccattacaca ttagtgctgt
    14281 tctatctgta tttgaatatt tttttattcc ttcaataatt ttcatataag aatgctcctt
    14341 taaaatccgt tataaataaa tggcaattct ttaaatggag taaatgttag aactcctatc
    14401 gccaatatta taaccatagt taaacaaata ctagttaaca aatctttatt gttctttaaa
    14461 tattttaaat aatctctcac agacatctac ccatcctttc gtaccaagat gcattacatc
    14521 ccttaaataa tacttatctg accctttatc tttaaggttt agaacttcaa agcctttgct
    14581 ttctgctatt ttttgtgctt tatcgtagta ctgatttctt tctttttcag aaataccagt
    14641 caaattatag aatttatcca tacttgggat taatacaaca actggcttaa tacctaagtc
    14701 agtacataca tttagcatca atttataatt ttcaaactcc ttagatgtta ataaatttac
    14761 atctttgtct cttcctttgt attgctctat accatcttta aaatgctctt tataatagta
    14821 cttatcaata tttagtggat ttttaccaac tcttttttta gcatcttcaa tggctttctt
    14881 tctctcatat gaccaattta ttggtctttt tctttttgtt gctctctttt tatctagctt
    14941 aattaatcgt ttataaagaa tacccttttc tttaagagct atacaatact ttcttccttg
    15001 aaaataaggc tctaaaagca ccttttcagc tttttcagga aatgtcttag gctcatatag
    15061 cttagcatat aatgcttctg ctttatactc atcacttccc cataataact tacttgattt
    15121 ttttgcatat tcaatcttat tttgtttaga tatttttgga ttatctaaaa atcgataaaa
    15181 ttgtattggt gaaaatctag actgataatg gtgacttgtg actccgtctt tttccataaa
    15241 ccattgcata gaaattaaca agacaacttt cttattatca atattaggat tcatacttcc
    15301 taatattgca gcatcttgta atgtctgagt ataggctctt ccaattgcaa acaccttatt
    15361 tttactccta tttgtattaa aatagtactt tggatgttgt tttgttgaat tactaagttc
    15421 tgatgacccc aaaatcataa tatccttttc tcttaaaaaa tgattatttg ctgtaacccc
    15481 tttatctttt atatcactta aagtatcatc cataattgga agtagatttt tctccctcaa
    15541 aagttcatca gttttagaat caagaaattt gtctagccca aataaaaata ctacgcctat
    15601 tataaaaggt gtaataaagt atatcaattt tctcatattt tctctcctct aaaaatattc
    15661 aaatttatgt tattattaat catattagtt ttgatatgta tattcaacta caaaattgta
    15721 ataaaatcgt caaaactttt tttgatactg ttacaaaatt gtaaaaaaaa agaaaaaaac
    15781 gccaaaaata aatttctttt tagcactttt tcatacttat aatttgacat tttaacactt
    15841 ggttaagtat acgccttacc ttaacttaaa attaaattta tttaagaata tatattataa
    15901 attcttatat tttctaatat aaactatata ctatcagctg gataaacaat actactttgt
    15961 cttcttatct catccataat ttccattact attattgaat tttcatgaga atttatattt
    16021 gattctattt tattgttatt tataagactt ataaactcta caagttcata atacattcct
    16081 tctatttctc taggcttttc ctctgctttt tcttttggaa tagatatatc ttcttctctt
    16141 ccatctctgt atttaataat agctttttca aatagattaa gcttttcaat tattatactt
    16201 ccctcttctc cttgtatttc agatggtata taagaatcag ctactttaga atactgaatt
    16261 atcgcatcca tatcatcata ttgaaataca gctgaacctt ctccatccac tccagtttga
    16321 agtatatgag aaactgcctt tacagttttt ggagcaccaa ataaattcac cataggatgt
    16381 atacaataca ctcctatatc cattaaagct ccatttgaca actctttttt aaaggcattt
    16441 tctataattc catttttata tttatcatat cttgaagaat actgacaata gcttccaaaa
    16501 aatcttctta ttttccctat tttatataag ttttctttaa ctgctttaaa gtttggaaca
    16561 catgtaattc tcatagcttc cataagcaat acattattat ctttggctgt ttttatcatt
    16621 gatttgactt cttttaaatt agatgctaac gacttttcac aaagcacatg ttttttgtgt
    16681 tttaaacaag taatggtttg ctttgaatgt aatgcatttg gagaagctat gtatacagca
    16741 tctatatcct tcgatttagc catttgttct aaatcatcaa aaaaaatact tgctccatat
    16801 agagttccaa attctctagc tttttctaaa tttctagaat atacagcaac caattcaaag
    16861 tctttaaccc tagatgcagc tcttagaaat atatttgcta tattgcttgt cccaacaata
    16921 ccaaatctta ttttacccat cataaatcac tccccatttt ctacacttta ttttaatttt
    16981 aataaaaaac tttacaactt atagatatat tataaaataa ttttatcaaa taaaaaagaa
    17041 agctaatttt aaatgatttc accattttaa catagctttc ttttaactac aatctaaatt
    17101 caacttatat ttttaaagtt atctttctac tatatcttta tttcccctca aaaattttat
    17161 agtaagaatt tcatccacaa acaatgttac taaaagtata gttacaacaa ttggccaata
    17221 aggtattata agactatata aactatcaac tatatacact tgaaaatatc taactccaat
    17281 aaatgtcaat atagtccaat atacagaaaa ctttagacat actattcctc tactattgta
    17341 cttataatct gaataatccc aatagacctt attaaaatat actttcataa gtattcctgt
    17401 aatatattct actactgtcg gcactactag acataataaa agcaatgcaa atatattatt
    17461 ggggtcaata aatcttgaga cctctattat aatcgacatt gcaattgcat acattggttt
    17521 aaatggacca tttaaaaatc catcttcttg aaaatgccct tgtttataat aactatataa
    17581 gttttcaatt atccaaccta taaaaccata caagaaaaaa ttaaataaaa aatataatag
    17641 agaacctaca ttatccatga atattcctcc tagctgttta tacttatttt ttctcatatt
    17701 catggattta ttctaaatca aagaaattat att
//
LOCUS       DAEOTL010000086        17581 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEOTL010000086 DAEOTL010000000
VERSION     DAEOTL010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17581
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.086"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            38..931
                     /gene="era"
                     /locus_tag="KRH82_003164"
     CDS             38..931
                     /gene="era"
                     /locus_tag="KRH82_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBG8656429.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCEKDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            943..2322
                     /gene="mgtE"
                     /locus_tag="KRH82_003165"
     CDS             943..2322
                     /gene="mgtE"
                     /locus_tag="KRH82_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBG8656430.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            2395..2550
                     /locus_tag="KRH82_003166"
     CDS             2395..2550
                     /locus_tag="KRH82_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBG8656431.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            2516..3289
                     /gene="recO"
                     /locus_tag="KRH82_003167"
     CDS             2516..3289
                     /gene="recO"
                     /locus_tag="KRH82_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBG8656432.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            3282..3881
                     /locus_tag="KRH82_003168"
     CDS             3282..3881
                     /locus_tag="KRH82_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBG8656433.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            4041..4919
                     /gene="glyQ"
                     /locus_tag="KRH82_003169"
     CDS             4041..4919
                     /gene="glyQ"
                     /locus_tag="KRH82_003169"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBG8656434.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            4919..6985
                     /locus_tag="KRH82_003170"
     CDS             4919..6985
                     /locus_tag="KRH82_003170"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBG8656435.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVTLLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFNKEEVVEQIMSFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(7151..8698)
                     /locus_tag="KRH82_003171"
     CDS             complement(7151..8698)
                     /locus_tag="KRH82_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBG8656436.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            8978..9745
                     /locus_tag="KRH82_003172"
     CDS             8978..9745
                     /locus_tag="KRH82_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBG8656437.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            10028..10225
                     /locus_tag="KRH82_003173"
     CDS             10028..10225
                     /locus_tag="KRH82_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656438.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            10254..11330
                     /gene="vorB"
                     /locus_tag="KRH82_003174"
     CDS             10254..11330
                     /gene="vorB"
                     /locus_tag="KRH82_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBG8656439.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            11333..12052
                     /locus_tag="KRH82_003175"
     CDS             11333..12052
                     /locus_tag="KRH82_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBG8656440.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            12065..12604
                     /locus_tag="KRH82_003176"
     CDS             12065..12604
                     /locus_tag="KRH82_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBG8656441.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            12761..13819
                     /gene="buk"
                     /locus_tag="KRH82_003177"
     CDS             12761..13819
                     /gene="buk"
                     /locus_tag="KRH82_003177"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBG8656442.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            13837..14730
                     /locus_tag="KRH82_003178"
     CDS             13837..14730
                     /locus_tag="KRH82_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBG8656443.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNVLL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            14760..15968
                     /locus_tag="KRH82_003179"
     CDS             14760..15968
                     /locus_tag="KRH82_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBG8656444.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            15992..17251
                     /locus_tag="KRH82_003180"
     CDS             15992..17251
                     /locus_tag="KRH82_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8656445.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT         6841 a         1960 c         3271 g         5509 t
ORIGIN      
        1 aattaaaaca agaagataaa aagttaggag acagttaatg ttcaaatcag gttttgtcag
       61 tatagtgggt agaccaaatg taggaaaatc tactttaatg aataatgtag ttggagaaaa
      121 aatagctata atgagtgata agcctcaaac tacaagaaat acaatacaag cagtatatac
      181 agatgaagaa atgcagatag tattcttaga tacaccaggt attcacaaac caaaaaataa
      241 attaggtgaa tttatggtaa aggcagcaac agaagctttt aaaaatgtag atttaatatt
      301 atttgtagtt gatgattcta aaaaaatagg tcctggagat agaaagataa tagaggattt
      361 aagaagtgtt aagacaccaa taattttagt tgtaaacaaa atagaccaac tagaccaaaa
      421 agatgagcta tttgatataa tcaaaatgta tgatagagaa ggtattttta aagaaatagt
      481 accaatatca gcattaaaag gaaagaatac ggatacctta ataaaagtta tacaaaatta
      541 tttagaagaa gggccaaagt attttccaga ttatatgatt acagatcagc cagaaagagt
      601 attaatagca gaacttataa gagaaaaagt tcttcactat cttaatgatg aaatacctca
      661 tggtgtagct gttgaaattg aaaaaatgaa agcgagaaat gataaggaaa tagtagatgt
      721 atctgctgta atatactgtg aaaaagattc acataaggga ataataatag gaaaaaatgg
      781 taggaaacta aaaggaatag gtaagtcagc aagacaagat atagaattgc ttttaggttc
      841 acaaataaat cttcaattat gggttaaagt caaagaaaat tggagaaatt tacaaaatta
      901 tataaataat tttggatata atgataaata aaggtgggtt atatggatag gaaactggat
      961 gcttcccaag atttattata tgaagtaaaa tcattaattg ataataataa agtattggag
     1021 ttaagagaat taatagagga atatcatata attgatatat tcgatataat ggaaaattta
     1081 gaggaagaca tgaaaattca attatttgaa gtacttcctt tagatatggc atcttctata
     1141 ttagaagaag gtagtgtaga gttttttatt agtattttat ctaaactgga tgtagaacac
     1201 tcgaaaaata tacttgaact tatgtctctt ggagatatgg cagacaagtt gagtgaactt
     1261 gaagaagaag aaagagaaca cataataaat cttttgaatc aagagaatgc cgattatgta
     1321 aaagagttac tattctatga tgaagattct gctggtggaa caatgaccac tggatatatt
     1381 tctataaata aagatatgac agctcttgag gctatagacc atatgagaga agaagctgaa
     1441 gaagctgaaa ctatttatta tatatatgtg gttgatgatg aagaaaaact agttggagta
     1501 ttgtcattaa gagaattaat aatagctaga gacgcaaata tagtagaaga tttgatgagt
     1561 gaaaatataa tctctgttta tgtagatgaa gatagagaag aagcagtaag attagtatct
     1621 aaatacaatt taatagcaat tccagtagta gacagacaag aaaaattaaa aggaataata
     1681 acagtagatg atataattga tgtaatggaa gaagaagcaa ctgaagatat gtataaattt
     1741 gcaggaagtt cagaacatga aagagaagtt gctgaaaaag aaaaccctac attgagagag
     1801 caaataatat cagcacttag aggacgatta ccttggttaa ttattacctt agttggaggg
     1861 ttgttggctt cgttaatact ttctaactta gactatataa tgaatcctgt atatgctcca
     1921 ttagtatttt ttatacctgt agtaattggt atgggtggaa atattggaac tcaatcatca
     1981 tctgttacag taataacatt atctaataag gatttaaatt ttagcaatgt ggttagagaa
     2041 ggtattgtag gtattattac aggtcttttg tgtagtataa taacaggtat tgtaatttac
     2101 tttgttatga gaaagttaga cattgtatta attgtttcaa tatcattatt tataaatatg
     2161 gttttaggtg caacaatagg tgcgtttatg cctgttttat taaaaaaaat ggatgcagac
     2221 ccatctacag tttcatcacc aattatatct acagctcttg atataactgg tatagcagtt
     2281 tactttataa taacaacggc attattgtca aaaattgttt aataacttta tgtatgattt
     2341 atcctcttct tactaaaaat ataagtataa atgtaagaag ggggtttttt aaaaatgaac
     2401 aatatcagtt gggaagtttt taaaaaaaca ggtagtatag atgcatattt atatttctgt
     2461 gattgcaaaa acatacatga agaaattgaa gaagtaaggg agaaaaaaga agacgatgat
     2521 aatcctgaac acccagggga tagtacttaa agctataagg tataaggaaa gtgacataat
     2581 acttacacta tttacaagaa agcttggaaa agtatctgca atagcaaaag gagctaaaaa
     2641 aaataagagc tctttgcttt catcatcaca gttattttct tatagcaatt ttaccttaaa
     2701 aaaacaaggt aatatgtaca aggttactca aagtgaaata ataaaaagtt tttataatat
     2761 atcctatgat atagaggcat tttcttatgc tacatatatt acaaaattag ttgaaaattc
     2821 tatacttgaa aatcagacta ataataggct atttatatta cttgcgcaga ctctgtattt
     2881 gtatacacag gataatacag acaataggtt tataacagca gcattcgagt taaaattttt
     2941 agactatata ggatttaaac ctatagtaaa taaatgcatt aattgtgaat gtaaaatttt
     3001 acaaaattct gtgtttaata tctacgaagg tggtatacta tgtagtaagt gtagtaaact
     3061 ttttgataat aatataaaat tagacttaac aactataagt cttatggaat atgtattaag
     3121 aaatgatatt ttaacatgta gtaaagctaa agtatcaaaa tatataacac atgaacttga
     3181 gaatattcta gacaagtatt tgaaagttta tgttgataat attaatttta aatcattaca
     3241 cgtattgcaa agtgtaaaaa ataataaggg agtggataat gatgagtagt aatataacta
     3301 ttgaaatggt tgattcagtc tttgaaagag ttccaggagc aacttatgca gaagcaaaag
     3361 aagcattagt aatgtgcaat ggagatgtaa ttgaggcagt aatatattta gaaaataaaa
     3421 aaaatacttg taattgtaaa gcaaaatctg ctaaagaaac tatggaagaa gtatttggca
     3481 aagatggaga aaatataaag tttcaattaa aagagcttct tagaaaaagt agtgtagtga
     3541 gaataatagt tgaaaaagat ggaaaaacta tgatgaacat tcctttaaca gttggagttg
     3601 ttggattagc ttttgtacca ttagctactt tagttggatt atcagctgct gttataagta
     3661 aatatcgtat aaaagttcaa aatgaagaag atggagaaat tgtagattta ggtgaattga
     3721 atgaagaaaa acttcacgtt ttgaagaata tgataactaa tgcagcaaaa gatgtgaagg
     3781 atgtagtagt tgacaaaaaa gaagatgaca aagatgtaac tgctgacctt atgaaagaag
     3841 aatctgaaaa gaataaagaa gacgaagacg aaaataaata gatataaagt gacttttaaa
     3901 aaatgaagag aagataatta taagaattat cactaacatt gacaaatttt atagaatttg
     3961 atattctaaa agttgtagaa gaactattaa aatagccttt cgtgtagacg agaggcttta
     4021 ttgttatagg agggattttt atgaattttc aagagatgat actggcgttg caaaaatact
     4081 ggtcaaagca aggttgtatc atgatgcaac cttatgatat tgaaaaaggt gcaggaacta
     4141 tgaatcctaa tactttttta agatcattag gacctgagcc ttggcaagta tgttatgtag
     4201 agccttcaag aagaccagca gatggaagat atggtgaaaa cccaaacaga ctataccaac
     4261 atcatcaatt ccaagttata ctaaaacctt ctccagataa tatacaagaa ttatatttgg
     4321 aaagtttaaa agagattgga attgacccaa gtgagcatga cataagattt gttgaagata
     4381 actgggaagc tgctacagtt ggtgcttggg gacttggatg ggaagtttgg ctagatggta
     4441 tggaaataac tcaatttacg tattttcaac aagtaggtaa tattgaatgt gagcttgaga
     4501 caggagaaat tacatatgga ttagaaagat tagctatgta cattcaagaa gttgatagtg
     4561 tttatgattt aaaatggaat gataaaataa cttatggtga agtatttaat aaagctgagt
     4621 atgaaaactc aatgtacgca tttgaattat gtgatgcaga tatgttgttt aatctgtttg
     4681 atatatatga aaaagaagca ttaagactta tggaaaatgg acttgtaata ccttcatatg
     4741 actatgtgtt aaaatgctct catgcattta atacattgga tgcaagaggt gcaataggag
     4801 ttagtcaaag agcttcattt ataggtagag ttagaaatat ggcaaagact gttgcagaaa
     4861 cttttgtaaa acaaagagaa gaaatgggat tccctctttt aaaggacggt gacaaataat
     4921 gaaaaattat cttttatttg aaatcggtgt tgaagaaatg ccatcaagat ttgtaggcag
     4981 tacactagaa caattaaaaa acaatcttag taaattattt gatgaaaata gaatagcttt
     5041 tgataaaata aatgcgtatg ggacaccaag aagacttact ttagtagtcg aaggattgag
     5101 tgatagacaa aatgatttag aagaggaaat aaagggtcct gctaagaaaa ttgctgttga
     5161 tgcagaaaat aatttaacaa aaccagcatt aggatttata aaaagcaaag gattaagcga
     5221 atctgacata tattttaaac aagttggaaa agaagaatat atatttgcga ctataaagca
     5281 agatggaaaa gaaacttcag aagtactaaa agacatatta ccagagacta taaaatctgt
     5341 agtattccca aaagctatgc gttggggagg aaaaaatctt aaatttgcaa gacctataag
     5401 atggatagtt acattgttaa atgataaagt attagagttt gatttagaag gaataatatc
     5461 ttctaatgta acaaaaggtc atagattttt aggtgaaagt acaatagaag ttgattctat
     5521 agaagattat tttgaaaaat tagaaaaaaa ttatatagtt ttagaccaaa acaagagaaa
     5581 agaaatgata agaaaacaat gtatagaagt agcaaattct ttaggtggag aagttgaatt
     5641 tgatgaagat ttacttgaag aggtaactta tttagttgaa tatccaactg ctttttatgg
     5701 agaatttgat gtggattata taaaactacc aaaagaagtt gttataactc ctatgaaaca
     5761 acatcaaaga tattttccag tacttaaaga aggaaaactg ttacctaact ttatagctgt
     5821 tagaaatggt gattcttaca gaatagacaa tgttaaagct ggaaatgaaa aagttttaga
     5881 agcaagactt gcagatgctt tatttttcta tagagaagat actaagagaa acttagaaag
     5941 ctacatagaa aaattaaaaa ctgttgtatt ccaagtaaaa ctaggaacta tttacgacaa
     6001 aactttaaga cttgaaaaat taagtgctga tatacttgat agtttaggtt tagtagatga
     6061 aaaggcagat actataaggg ctgctaaatt atctaaggca gatttagtta ctggaatggt
     6121 aggagaattt gatgaattac aaggttttat gggaaaagaa tacgcaaaag ttggaggaga
     6181 gaatgatgtt gtaagtgaag ctatttttga acattatctt ccaagatttg caggagatat
     6241 acttcctaag actaatgcag gggttgcctt atcaatagct gataagttgg attcaatagc
     6301 aggtttcttt gctataggaa tacaaccaac aggttctcaa gacccatatg ctttaagaag
     6361 acaagcttta ggtatactta gtatacttat ggacagaaaa gttgctgtgg atataaaagt
     6421 acttattgaa catgctttag ataattattc tgaattagat tttaataaag aagaagttgt
     6481 tgagcaaata atgagtttct tcaatgagag agtaaaaaat ctatttaaag atttaggaat
     6541 aagatatgat gttgttgatg ctgttttaag ttctgatata aatgatgttt ctgatatgca
     6601 tatgagagct ttagagctta ataattggct agaaaaagat gaattagtgg agatgcttac
     6661 tgcatttaat agagtttcta ctctagctca aaaagcagaa agtgataaaa ttgatgaatc
     6721 tttattaaaa gaagatgctg aaattaaact ttacaatgaa tttaaacaag taaaggtaaa
     6781 agttaatgaa ttattaaagg ataagaaata tggtattgct ttagatgaat ttgcatcttt
     6841 aagaccagta gttgataatt tatttgatac agttatggtt atggataatg atgaagctat
     6901 taagaacaat agacttgctt tacttaaaca agtatatgat actatgctag aaatttgtga
     6961 tttatctaaa attgtttata aataaaattt aaactattta taagaaataa ggctgtctca
     7021 aaatagagat agtcttattt ttcattgttg agatgatgaa aatatatttg atttcataga
     7081 aaaagagtgt ctcataaact aaaaagttca ttttgagaca cccatgtttt ttgtaagtaa
     7141 atataataaa ttatatttta tacttatcag ttattttgtt taaaatatta tcatttgaat
     7201 ttacccattc ataaaaattg cctgatgatg cgtccgatat tttataaagc atttcaggaa
     7261 tatcactagc tttaaaatct ccaagtgatt ttcccaatct agtcttacct atttcaaaac
     7321 tgcctccaac aaataattca aatgcatctg tagatatacc atcaacattc ttctttttac
     7381 cacataaacc tatgctacca acttgatgaa caccacatga atttaaacat cctgatatat
     7441 ataacttagg tgctttattt aaaatttctt cattattttg taatctaaaa taatctatga
     7501 tttcatgtaa cattttctga ctattttgta tgcccatttg acaaattgga acacctatgc
     7561 aagatatact ttgttctaat tgagaattac aactaatagt tttacttatt tctaatattc
     7621 tttttgcttc atttccattt aaatttaaaa tatataatcc ctctgtcatt cctagtctaa
     7681 tcataggatt ttcaacatta tctaattctt taagtaaagt acttaaatcc tttgttaaca
     7741 aaatacctcc aactggatgt atatatacag tgtataaacc atcctgtttt tgaggtatta
     7801 gtctagaatc ttgtatatct attttaactc caggtttaga gtaatctatt tcttcaatat
     7861 tgagttcaag actaccattt tctttttcta atttatagta ttctttaaat ttttctaaga
     7921 atagttcttc accaagtgat tcgaccatat atctaaccct agctctattt ttattttcat
     7981 aatttccata atccataaag aatttaatca taccttcaac acaatataag gcgtctttcg
     8041 gctttataag ttcatcaagt tctaaagcaa ctttgggctg tttacctaga cctccaccta
     8101 agaaaactct gaaatatggt tcatcatttt tcaaagtagc aacaaatcct aagtcttgta
     8161 tactacaatg agcagtatct gtgtaacaat tagaataaga aacttttaat tttctaggta
     8221 aatggtatgt agtagcattt ttgataaaat atttatcagt agcaactgca tatggagtaa
     8281 catcaaagac ttcactaggg tcaactccag ataatggaga taatccgaca tttctaggat
     8341 aattaccacc accacctcta gtgaatatat cattttttat tccttcttcc atgatatcaa
     8401 caattgaatt tatagataaa tcgtgtaatt gtatagcttg tctagttgtt aagtgtatct
     8461 tatctaagtt gtgtttaata gctatttcat agattttatt aagttgatac tgagataaaa
     8521 ctccagcaga tactctaagt cttatcataa aagatttttt gtctctttga gcataaacac
     8581 catatccacc agaaaatccc ttatattgca ttttatttat ttctccattt aaaaattttg
     8641 aagaatattc tttaaaatta ggtagttcat ttaacaatat ctttttaaaa ttatccatta
     8701 tttcacctca ttgttagtct tgtataaaaa tatatctatt gtataataga tatatatatt
     8761 attatctagt caggataaaa atataacaga ataattctat taaaagtaag aataataagg
     8821 acatagtgag tattttgttt ttattttaca aattaagtat aatatttttg ttttataaaa
     8881 tataattaag ataaatagat aattttgtaa ttttaatata taatatttag tagagtgtgg
     8941 gagtagcact taatatttgc aggaggagtt tttgtatatg ggagaaataa taaatgcatt
     9001 agatagagcc ctagacataa ttttgctgtt atatcatgaa aagagagaaa tgggaataac
     9061 tgaaataagc aaggctatgg gagtatataa aagtactgta catagaactt tggttactct
     9121 tgaaaacaaa ggttttgtta tacaaaatgc agagaatggt aagtattggc taggaataaa
     9181 tttatatgca ataggtatgg ttgtgggaga aaaaatgtca ttgactgaaa tagtaaaacc
     9241 atatacgaaa aaattaaatc aagaatttaa cgaagtagtt aatgtatcta tattagaaga
     9301 aagagctcaa gattctccaa gaagtatcat aatacataaa gagtatggtt caaatcaatt
     9361 actttcagta aatccatccg ttggttcaag tagtgaatgt tattgttcag cagttggtaa
     9421 atgtcttatg gcatttaatg attctataga ttttgaaaaa tatagaaaaa caccaataca
     9481 caagtataca gaacatacaa ttgataattg ggatgatatg atgctttttt tagcaaaaat
     9541 aaaagaacaa ggatatgcta tagatgatga agaactagaa catggactaa cttgtattgg
     9601 agcacctatc ttagataaaa ataataaagc tattgcagcc ataagtttgt caggtccaac
     9661 tataagaatg agagaagggg actttgagta taagattaaa agagttatag aaactgcaaa
     9721 aagtatatct gaacttttta gatgattttt aatcttgata ataaaaatag gctatattta
     9781 aattgttatt tgtaaatatc aatttaaatg tagcctattt ttctttaatc taaaattaaa
     9841 tattcttaaa atttaaaatg ttattgaaat atataagcga atgtgttatc ttttaattaa
     9901 gcaataaaaa tagaacaagg ttctatacta tagaacaaaa ttgatgcata tatagtattt
     9961 atacaaaata taaatattat atatttaaaa ttaagtaaaa atattacata aaggggagat
    10021 ttgagaaatg gaaaaagtca agttgagtgt tgaaagatgt aagggatgct atctttgtat
    10081 tgaagcttgt aaaaaagatg caataagtct ttctgactac acaaataaaa aaggctttgt
    10141 aactattaaa gtcgatgaag aaaaatgtat tcaatgtggc gcttgttata caatgtgccc
    10201 tgatttagta tttgagatat tataaattat ttttattaga ggggagaaaa ggtatgcaaa
    10261 gtttattaat taaaggaaat gaagctttag cagaaggtgc tatacgtggt ggctgcagat
    10321 tttatgcagg ttatccaata acaccacaat cagaaatatt agaaatgatg gcatggagac
    10381 aaaaagaagt tggaggagta tttatccaag gtgaatcaga aatagccagt gtaaatatgg
    10441 ttatgggagc aagtgcactt ggagcaagag ctatgacttc ttcatctggt ccaggatttt
    10501 cattaaaaca agaaggtatt gcatattggg tatcagctgg tttgccagca gttgtagcat
    10561 gtgtgcaaag atatggtata ggtgatggat ttataggagc tggtcaagat aattattggc
    10621 aagcagtaaa aggcggtgga aatggagatt atcatttaat cgtgttagca cctaatagtg
    10681 ttcaagaaaa tatggatatg gcatatgaat cttttgaatt ggctgaaaaa tatatgcatc
    10741 cagtacttat actttctgat gctacaatag gtcaaatggt agaaccttgt atagcaccac
    10801 caatgaaaga atacgatatg gataaagctc catgggctgc aaaaggaaca cctgtaggag
    10861 aaaaaaataa agtaataact gatataacat attttgaaga ccaagataca tggcaaaaag
    10921 ggtatataga aaaaatgaga aaagttcaag aagatgaaca aagatgggaa gagatagaaa
    10981 tagaagatgc tgaagtggta tttgtggcat acggtatttc atcaagaata gcagaaggtg
    11041 cagttagaga tgctagagca aaaggaatga aattaggtct aataagacca aaaacattgt
    11101 ggccttaccc aagaaaagca tttaagaaat taagtgattc attgaaggga cttgtaacag
    11161 ttgaaatgaa catgatggca cagatgaagg aagatgtaat tatagcatgt gataatagat
    11221 ttccagtata ttcagtagca acagctcaat atatggcaga agtaaatcaa ttaatagatt
    11281 ttgctcaaca gattatagat ggaaaagcta agcaagagga ggtattttaa ttatggctaa
    11341 aaaagcacca gcaataatga tgtgtgaaaa tatgttctgt ggaggctgtg gacactctat
    11401 agtcgataga attattggag aagtattaac agaaatggat atatgtcaag atacaattat
    11461 atgttcagat ataggttgta atcatatgtt tcaatttagt atgaatgtag atgttgtcgt
    11521 tccacctcat ggtaaaatgg gagcagcaat ggcagctatg aaaagagtta gaccagataa
    11581 atatatattt acaatagctg gagatggtgg agcttatgca atagggcttg gagaaactat
    11641 gtcagctgct actagaaatg ataatgtaat atttcttgtt atgaacaata atatgtttgc
    11701 aatgacagga gggcaaatgg ctccaactac tatagaaggt caatatacag cttctactcc
    11761 agcgggtaga aattacgcag atcatggttc aacatttgat gttgtaaaag ttatgggaaa
    11821 tttagatata gcatatctag caagaggaac aataactaac cctaaagaaa taaatacaac
    11881 aaaaagatac atcaaaaaag ctctagaaaa acaaaaagaa aagaaaggtt tttgcttaat
    11941 agaagtgctt gtaccatgtc caacaaactg gggattaaag ccagtagatg ctatgaagag
    12001 aattgaaaat gaacttgttc caaagtatcc acttggagaa tttattgatt agggaggaaa
    12061 taatatgttg aatgaaatta tatgtgctgg ttttggagga cagggagttc ttacagcagg
    12121 aaaaattata atgtatgttg catataaggc agaaaagaaa attacatggt tcccatctta
    12181 tggaaatgag atgaggggag gaagtgcaaa ttgcaatgtt gttgtaagtg atgaaaaaat
    12241 tgcaaatcct tgtgtaaaaa atccagatat actattggga atgaacagcg tatcagtaga
    12301 taagtatgaa agtttaatga aaaaaaatgg ttatatgttt gtcaatgaat cactagtaag
    12361 taaggataga aagtacagag aagacattaa tgttataaaa gtacctgtta ctgaaatagc
    12421 acaaaattta ggcaatgaaa aagctgctaa catttgcatg ttaggtgcta tggtaaagag
    12481 tttggattta tttacaaaag aagaatttga aagtggtatg tgtgaatact ttgaaaatca
    12541 aggcaaaggt aaattcaatt ctaaaaatgt agaagcattt gaagctggat acgactacga
    12601 atgaatattt taaatattta aaataattat tgaaatactt atttttatat gttagtattt
    12661 aattaataaa atatagaacg tcgttctgga caataggacg aagtctttag gtcggaatac
    12721 aagaacggcg ttctgtatag tagaactagg gggtgttaaa ttgaaagttt tagtaataaa
    12781 tcctggtggt acatccacaa aaatttctgt tttccaagat gaaaatgaaa ttttgaaaaa
    12841 aaatataacc catacaagag aagatttaaa aaatttttct aaagtatttg atgaatatga
    12901 ttatagaaaa caactgatag tagatatttt aagtagtgag aatcatagta taaattcttt
    12961 tgacgcagta gttggtcgtg gtggacttat gaaggctata aaaggtggta cctatactgt
    13021 gagtgaagaa atgattgagg atatgagaaa tgaaataaat ggggaacatg catcaaattt
    13081 aggtgcatta ttagctaaaa ctatagctga tgaaatagga gtacaatcat ttgtagtaga
    13141 cccagtttct gtagatgaat ttgatgatgt atcgaggatt acaggaatat cagacataga
    13201 aaaagcaagt tggttacatg cattaaacca taaagctgtt tcaagaaaaa ttgcacaaaa
    13261 actaggggga aaatacgagg attataactt tattgtagct catttaggtt caggaatatc
    13321 gattgtagca cataaacaag gcaaaatgat tgatggaagt ggtggtaggt ctgatggtcc
    13381 attttctcca gaaaggagtg gtggattact tgcatatcct cttatagaat tgtgttactc
    13441 cggaaaatat actcatgatg aaatggtcgc aaaagtaagt tcgattgggg gaatgtacga
    13501 ttatttagga acaaaggaca tgatagaaat tgaaaacaga atcaaggagg gtgatgaaaa
    13561 ggcaaaactt ataatggatg catttattta tcaagtagca aaagaaattt ctatgtatgg
    13621 agcttcactt tcagggaatg tagatagagt tatcttgaca ggagggatat ctcactcaga
    13681 aatggtagtc aaaggagtag cagaaaaagt ttcatatcta gctccaatag agatagtacc
    13741 aggagagatg gaaatggagg cacttgctct aggggcactt agagtactta atggagaaga
    13801 aatagcaaaa acttattaat atttaggaga aagagtatgt taaaagattt taataattta
    13861 ttagaagagg ctaaaaagct tgaacctgtt attgtaagtg ttgctgttgc agaagacaaa
    13921 gaagtattaa aggctgtgaa atcagcaaca gatttaaaca ttataaagcc aattcttgta
    13981 ggagacaagg ataaaataga aagtatatca agagaaattg gattaaaagg tcatgaaata
    14041 ataggttgtc aaaatcccga tgaatcagtt aaaaaagctg tagagatagt taaaaataag
    14101 gaagctaaag ttcttatgaa gggattagta aatacaagtg tctatatgag agctatatta
    14161 aataaagaaa cgggtcttag aacaggaaga ttattaagtt tgcttgcagt atatgaatta
    14221 cctcaatatc ataaacttct ttattgtact gatagtggaa taaatgtatc gccaaactta
    14281 aatcaaaaaa aagatataat gacaaatgta cttcttacta tgaaaagtat aggcatggaa
    14341 aatcctaaaa ctgcgatact tactgcaaat gaaatggtag accctaagat acaatctaca
    14401 gtggatgcca acctacttgt agagatggaa aaatcgggag aaataccaaa gtgtatagtg
    14461 gaaggtccaa tagcatttga tgtagcattt gatgcacatg cagcagaaca taaaggtatt
    14521 aaaagtaata ttgctggtga tgttgattta ttagtatttc caaatataga agcagggaat
    14581 atattaggaa agtcatggct tagatttaat aaagctaagt gggcaggtat agttttagga
    14641 gcaacaaatc cgataatttt aggttcacgt tctgacacag ctgaaataaa aataaattca
    14701 atagcattag cgtgcctagc atcacaataa gaaattatta ttaaggagga aaaagtgtta
    14761 tgaaatatgc aaaaagaatg gatatggtaa aagcttcagc tataagagat tctcaaaaga
    14821 aaatagctca gaaggtagca agtggtggaa ctgttatatc ttttgctgca gggcttcctg
    14881 acccaaattt atttccaata gaagagataa gtgaaataac tcaaaaagta cttaatgaaa
    14941 ggggaaaatt tgccctagca tatggaccta ctaaaggtga agatgagttg ttagatctat
    15001 tagtaaaaag aatgaaagaa gaagaaaata ttgatacaaa agcagaaaat attataataa
    15061 ctactgggtc acaacaaggg atagcattaa gtgctatgat tttattagaa aagggagatg
    15121 tagtagttac agaaaatcca agttacttag gtgcaataaa tgcatttaga ccttatgaat
    15181 gtgatttttt aggagtagat acagatgaag aaggaatggt aacagatgat ttagacaaat
    15241 tattatctga aaattctaac ataaaggtga tatatgtaat accaacattt caaaacccta
    15301 caggaaaaac atggtcttta caaagaagaa aagattttat ggaagtcgtg aataaatatg
    15361 atgtcatagt aatagaggat aatccttatg gagaaataag atttacacca gaacctctac
    15421 ctacacttaa atctcttgat actaaagata aagtattgta ccttgggtca ttttcaaagg
    15481 tattatgtcc aggatttaga gttgcttgga tgtgtggtaa tgtagacatc atagataagg
    15541 cagaactttt aaaacaaggt atagatttac agtcaaatca attttcgcaa gtacaagtaa
    15601 tagaattttt aaagaaatac aacttaaatg aacatataga aaaaataaga gcagagtata
    15661 agaaaagatg tctgctaatg ttagatgcta tgaagaaaca tttcccagag gaagctaaat
    15721 atacagaacc agatggagga atgtttatat gggttgaact tcctgaaagt ataaatgtag
    15781 atgatttatt agataaagcc attgatgctg gagttgctta tgtttctgga gagtccttct
    15841 ttgcaaataa tggtccaaaa aatactatga gacttaacta tacaacaatg tcagaagaac
    15901 aaatcgttaa aggtgttgag atacttgcag aagttataaa aaaagaactc aattatgctt
    15961 gtgaataaat ataaaaagtg agggtttaaa tatgggagaa aaagaaaacg gtataaagtt
    16021 tggaaagtta atgtttcaac ttgttattat agcaatatct tgggaattag tttatattat
    16081 accatttatc caatatacat tatatgatcc aatcctaaaa gcattagaat gtacaaacac
    16141 tcaactaggt tttctactta caatttatgg gttaggtaat atatttggag ctcctatagg
    16201 aggctggtta gcagatagat ttgattatag aaagataatt ttaggttctg tatttcttaa
    16261 tggagtagta tcatttttat ttgcatttaa tatgaactat ccatttgcag ttgctacttg
    16321 ggtaggttgt gcaatcacat cattagttat gaactatcct tctatggtaa aaatacttag
    16381 agttatagga aaagataatc aaggtaaggt ttatggattt aatgaagcta tggttggagt
    16441 ttctggagta gtaatgggag caatattctt atatatttat acatgctttg caactcctac
    16501 attgggtatg agatgggtaa tgatatcttt aggaatatta tcaatagcaa tgtgtccagt
    16561 attatggttt gtaattaaag atgtagatat taaagaagaa agagaagaag caggtgaaaa
    16621 aatgtctgct ggtgatttta taacagtact aaaatcacca aatacttggc tagtaggaat
    16681 aagtatattc tgtgtatatt cattcacagt tacaatgtct tattttacac catatataac
    16741 atctgtactt ggaggttctg tagcattatc tggtgcatta gcaataataa gacagcatgg
    16801 tctaaaatta tttggagcac catttggagg atattgtgca gacaaattaa aatctcctac
    16861 aaaagtactt ttaccaatat atgtatttgg tatagcagta atagttttat tcctagtatt
    16921 acctgcatca actccaatga ctatattcat agctttaaca tttgtagtag gtatattagg
    16981 ttacatggga aaaggtatat attatgcagt acaagatgaa gtaaaagttc cagttaaata
    17041 ttcagcaact actataggta tagctgcagc tttaggattt tcaccagatg tattccaatt
    17101 tgcattaata ggacactgga tagatactta tggcaataaa ggttacacat atacatttat
    17161 attccaaata gcaattctag ttattggaat actatcttgt ttatatatat taaaggttaa
    17221 aaagagaaga gcaagtaaat tagaagctta aatattcaat ttggtaatta agtatatata
    17281 aatacaatac ttattttgat gaatgtgatt gtataaataa cataaaaaat atcaatagat
    17341 taagttttat aataatgttt agagaataaa gtataaaaat caaaatgtta tcaagttttc
    17401 taggttttaa cataaagtta cccctgaagg tgtaaaattg agtggcaatt attatctatt
    17461 ttcttaccta cataaaccta tttaatttaa attctaagag attttcaaaa tagatggtag
    17521 ttgtactcaa ttttaaacct cataataaat acgaaaattt aaaatctaac tagatactat
    17581 t
//
LOCUS       DAEOTL010000087        17388 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEOTL010000087 DAEOTL010000000
VERSION     DAEOTL010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.087"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..855)
                     /locus_tag="KRH82_003181"
     CDS             complement(<1..855)
                     /locus_tag="KRH82_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBG8656446.1"
                     /translation="MKAGEIEFLSYLEGSNKSFVVPVYQRNYNWKKEQCKRLFDDLED
                     IIDSGFRTHFLGSVVSIYSMGKEYLIIDGQQRVTTVSILLIAMCQIIKEFGESKGIIT
                     TEEQIKECYLINKHSRDKDGKIKLKPIAEDRKAYYELFEEEMNTDRNSNIVSNYLYFY
                     NRIKEDNISIDDLFDAIQKLTIVEIELKNGEDDPQLIFESLNSTGLDLSEADRVRNFV
                     LMGRSSKLQEEFYNNYWYKIEKNTSSNVSSFIRDYLTIKERSIPNKNKVYFSFKRYVS
                     DNGIDIEIL"
     gene            complement(1236..4571)
                     /locus_tag="KRH82_003182"
     CDS             complement(1236..4571)
                     /locus_tag="KRH82_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBG8656447.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYANDSDLVLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLYGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTVNYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIGEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLSSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKAETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEYRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRRLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(4620..5048)
                     /locus_tag="KRH82_003183"
     CDS             complement(4620..5048)
                     /locus_tag="KRH82_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656448.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDYLLACEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(5038..5418)
                     /locus_tag="KRH82_003184"
     CDS             complement(5038..5418)
                     /locus_tag="KRH82_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBG8656449.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTEALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(5451..5759)
                     /locus_tag="KRH82_003185"
     CDS             complement(5451..5759)
                     /locus_tag="KRH82_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656450.1"
                     /translation="MNQIELDLYHNMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(5792..6976)
                     /locus_tag="KRH82_003186"
     CDS             complement(5792..6976)
                     /locus_tag="KRH82_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBG8656451.1"
                     /translation="MVDEAKILDVVSISGENVKKFDGERSYLSTGNLDFNKISNLEIV
                     TYENKPSRANQTVNIGEVIFAKMKDTKKTLVINKTNKNIIVSTGFYVLKPSKEILPQY
                     LYHYLNSSYFLNQKNRLSKGATQSALNNEGLANIKIRMYNLKVQEKVVRVLDKAQELI
                     DKRKEQIEVLDELVKSRFIEMFGTPSKNEKNWEISEIGKYLDVLTDYHSNGSYETLRD
                     NVTLLDTKGYALMVRTTDLENNNFEKGVKYIDEHAYNYLEKSKVFGGEVIINKIGSAG
                     KVYLMPFLNKPVSLAMNQFMLRFNEDKVNHIFLYNLLLTSYMESKIKEKVRGAVTKTI
                     TKDAVRKINIIVPPIRLQNQFANFVKQVNSLKFEMETSLKELEDNFNSLMQKAFKGEL
                     FN"
     gene            complement(6980..8443)
                     /locus_tag="KRH82_003187"
     CDS             complement(6980..8443)
                     /locus_tag="KRH82_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBG8656452.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFNDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIMGRVKALEKEIVDGLEELERMLEV"
     gene            complement(8953..9822)
                     /gene="gatY"
                     /locus_tag="KRH82_003188"
     CDS             complement(8953..9822)
                     /gene="gatY"
                     /locus_tag="KRH82_003188"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBG8656453.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKNVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIETVKC"
     gene            complement(9842..11758)
                     /locus_tag="KRH82_003189"
     CDS             complement(9842..11758)
                     /locus_tag="KRH82_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBG8656454.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNATKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(11761..12681)
                     /locus_tag="KRH82_003190"
     CDS             complement(11761..12681)
                     /locus_tag="KRH82_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBG8656455.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(12783..13535)
                     /locus_tag="KRH82_003191"
     CDS             complement(12783..13535)
                     /locus_tag="KRH82_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8656456.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(13927..15372)
                     /locus_tag="KRH82_003192"
     CDS             complement(13927..15372)
                     /locus_tag="KRH82_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBG8656457.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDDVEEAKYQ
                     AIHHQFMATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRIQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVIEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(15394..15747)
                     /locus_tag="KRH82_003193"
     CDS             complement(15394..15747)
                     /locus_tag="KRH82_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBG8656458.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEADGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(15776..17023)
                     /locus_tag="KRH82_003194"
     CDS             complement(15776..17023)
                     /locus_tag="KRH82_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8656459.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTIVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(17031..17348)
                     /locus_tag="KRH82_003195"
     CDS             complement(17031..17348)
                     /locus_tag="KRH82_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656460.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
BASE COUNT         5430 a         3331 c         1738 g         6889 t
ORIGIN      
        1 taaaatttct atatctatac cattatctga tacatacctt ttaaaactaa aatatacttt
       61 atttttattc ggtatacttc tctcctttat agtcaaatag tctcttataa aactacttac
      121 gttgctactt gtattttttt caattttata ccaataatta ttataaaatt cctcttgtaa
      181 cttagagctt ctacccatta acacaaagtt tcttactcta tcagcttcac ttaaatctaa
      241 gccagttgaa tttagacttt caaagattaa ttgagggtca tcttcaccat tttttaactc
      301 tatttctact atagttaatt tctgtatagc atcaaacaaa tcatctattg atatattatc
      361 ttcttttatt ctattataaa aatataaata atttgaaact atattagaat ttctatctgt
      421 attcatttct tcttcaaata gttcatagta cgcttttcta tcttctgcta ttggttttaa
      481 ctttattttt ccatctttat ctcttgagtg cttgtttata agataacact ccttaatctg
      541 ttcttctgtt gtaataattc cttttgattc cccaaactct tttattattt gacacatggc
      601 aatcaataat attgacacag tagtcactct ttgttgtcca tctattatta aatattcttt
      661 tcccatacta tatatagata caactgaccc taagaaatga gttctaaatc cagaatctat
      721 tatatcctct aaatcatcaa acaatctttt acattgttct ttcttccagt tataatttct
      781 ttgatataca ggtactacaa aacttttgtt tgacccctct aaataactaa gaaattcaat
      841 ttctcctgct ttcatattaa ctccccctat aagttaaata aattccattc ataactccat
      901 gtatctatat attatatcaa aattttgact cataaatgta tatgaaagcc ttattatata
      961 cctttttata cctgttttta ttttattaaa gtaaatacat gattattcta taaaatatac
     1021 aaatacttaa ttttaaaaat tattatttaa tcttcttcat gagtaattca tagttattta
     1081 tcaattaaaa agagatattg cataattatt caatacctct ctttgtatat ttacattatc
     1141 catatctagt tatctatttc aacccaatat tagactacct actaataaat ttattctcta
     1201 catcattaac aataattttg cactaaataa catcattagc ctatctctga tgcattttct
     1261 ttaattttat ttatagtttt aatcaattta tttctctctt caatatgatt ttcaaataaa
     1321 tcaattatac ttccaacagt tctaaatggg tcttccatca acactttgtt atcctctata
     1381 aatccattct tgactacata atcgactata agtttaacaa aatgtatttg cttagtatta
     1441 aagctcttat tatttaaaaa ctctgaaaaa gcttcatttg cagcttctct atccaatccc
     1501 actagtcttc tcactaattg gcttactgga gtatctccaa actccttctt ataatcatca
     1561 caattaccta actgttttaa gagtatttcc tccaacgttt caacatcttg ctttgttatc
     1621 tttttattat ttcttaattt aaatattgct aattcatctt tatggctatt taaataatac
     1681 tctaccttct ttttataatt cttaagattg tttgcattat atacagaatc atttctatat
     1741 tctgctacaa tcatatcttc aaaacttgta taatatatct tttgactaga cttttcaaga
     1801 tacttaataa gctctcttaa tgatatacgt acttcttcta cctcaaatat atctgaatct
     1861 tcccaaaaat cctctgtcat tgctttttca atagtatatt tttgttgctg aatctgtggt
     1921 atagtcccaa gttttgaaag tttttctgct gtagccatta catgccttat acctttactt
     1981 gcattattat tttgtaagta tgcaagttgt atattataca taactacatc aaatctttta
     2041 gccaattcat catcactata tgaagttatg agtggtgata tatattctct tatctcattt
     2101 tgtgctactg ctccaatatt gctccaaaca ttttcatttt tatacttatg tacataactt
     2161 aaattcatcc taactatata actatcctca tttaaagctt ttacagaagt tataagttct
     2221 tctaacaatt cttttctaag ttctgcatac tcaccttcta tatatttaat atcttgaagt
     2281 tctttaacca tacttacctt tatattaaat aatttttcag taagtgtttc tgctttattt
     2341 ccctcaaatc ctttaggatt aaatttaaaa aattcaaaat tattacaaaa atcaaatatt
     2401 aagaatctct ccttatccat atcaacacct aataaatctg gacataatct agttcctcta
     2461 cctatcattt gccaaaactt agtcttactt ctcactttct tgaaaaaaac aagatttagt
     2521 atttcaggta tgtcaattcc tgtatcaagc atgtctactg aaactgctat ttgaggtaat
     2581 ttattcttat cagaaaaatc atctattata gaatctacat aatttatact atagtcaact
     2641 gcttttacaa agttcccacc atactttgga tacagcttat taaatctttc aactattgcc
     2701 ctagcatgct ttgtattctt tgcaaaaatt atagtcttac caatcttttc ttctccttct
     2761 attttcaacc cctctgtcat tagcttattt aaaactaaat ctattgtgtc agaattaaat
     2821 agccactcat ttactgcatt attccctatt tcgtctccaa tactctcatc atcattaaat
     2881 gtattttcat attcttcctt ctcttcatca gaaagctcat catacttaat tccatcttcc
     2941 ataatcttag tcttaaactc aatactagta taatctacta aatatccatc ctcgactgcc
     3001 ttattatact cataagcata tgtaggtact ccattttcca tgtcaaaaac tgaataagta
     3061 tttttatcta tctcatcctt tggtgtagca gtaagaccca ttaagtaaga atcaaaataa
     3121 tcaaagattg acttatattt tttataaata cttctatgcg attcatctat tataattaaa
     3181 tcaaaatggc caggtgtaaa caatctcttt ccatccttag acttcgtatc atcaattgca
     3241 ttcatcattg ttggatatgt agaaaatatc atcctagcat cttctgggct gtctttgcta
     3301 tccaataaat tacataacgc caagttaggt aatagcttag taaaactttt tttagcttgc
     3361 tttaccaatg cttttctatc tgctagaaat aatatatttt taatccaatt atgtcttgaa
     3421 agtacatcaa ctatagatat agcaattctt gtttttcctg taccagtagc acataccaaa
     3481 agagttttgc gttgcttatt ttcaagagcc tcacatacag ccctaatagc ttctttttga
     3541 taatatctat tggatatttc atcatttatt gttacagaac ttaaagactt cttactcttt
     3601 cttctatcta tcataagttg taattctgat tttttataaa atccataaac ttttctatct
     3661 gaatagtcat cccaaatata catatcaaaa ccattagtca aaaatattac tggtctttga
     3721 ctatatctct tttccaaaca atctgcatat aatttagctt gttgttgacc aatttttgga
     3781 tctttactcg ttcttttcgc ctcaactact gctaatggct taccattttc accataaaga
     3841 acataatcta catatcctac accactttca ttaggcatac cttgtacttc tatttcctcc
     3901 cctatatctt ttccaaattc ccaacctgca agctttaatt ctatatttat atatcttttt
     3961 cttgtctcaa attcgcttac ttcgtctatc ttgaaatcat agtttacagt attaactttt
     4021 ctcttttcag ttagtgactt tcttaattcc tcattttctt ttattacttc ttcaagcttt
     4081 ttatcttttg aacttaatct ctcataaaga tttttaagtt cgtccggtct cgtccttttc
     4141 tcttccccat aaagtaataa atcttcatta aagtcttctg ctgtatattc atctgaataa
     4201 caatagtcta tccaactaac aaattgatgc aaattgttaa gtgaaagtat tgcttctcct
     4261 ctctctatgt tcgcactagt atgtacagat aaattaccta atttaactat atattttaat
     4321 aaaggtaaca tatcatagtc tataagttct ataaaactat tattatgaat caacgtactg
     4381 agattatctt gataaggcaa tactaaatca ctatcattag catatagcca ttttactgca
     4441 agctctaaag ctcttcttgt tatagttgca caagtagatg gactaactag tatacttttt
     4501 tctgcttcta agcaagcagt attaaaacta ttgaaatttt tcttcttttg taaaaaatca
     4561 aaattaccca agcttttatc ccccttttgt cccttagtta aaataaatct ctctaaaaac
     4621 tatttcttac agctgtttct tatactaaca aatacttctt cattttctgt aaacaattcg
     4681 tacatatctt caaactgtgg tatatcatat ccatgagaat catcatttct caattttcta
     4741 agtgtttcta taactataga agaattttta ggtaataaat tgtgatactc acaagctaaa
     4801 aggtagtcat aaaagttttt agattttatg tttaaatcaa ttgatttata atacaacatt
     4861 gcttttgtta attctagaaa tgataccata tagcttttaa agccttcttt tatgtatcta
     4921 gcccataact caggcatttc ttccttatca tataagattt tgaagttttg caggtcatac
     4981 aagcaagaac caaaatccct atttacttct tctattgagt tccaagataa tttgtttcta
     5041 attaccatac atgtccctcc aatctaagat atctattaca tcactgtttt caaaatagaa
     5101 tttatttata taatccttaa aatctttaga ttcataaata acttcacctt ctaaaatagc
     5161 ttttttaagt gctattgtat aattatctgt aacaattttt aggtctacat caatgtctaa
     5221 tatatttctt agagcttctg tcttagttgc aagttctgta attggtactt ttttgatagg
     5281 aatccaagct atgtctatat cactttctga tgtatgttta tctgttccat aactaccaaa
     5341 tattatgatt gctagagtat tttcttttgg aaatacattt attattgagt ttttaatctc
     5401 atttggtata tttctcattt aatcacctct tgtttattag gtaatattac ttaattaaat
     5461 ttatatccat aatcttttaa tctatttata catatttctc tttcttcatc agtaaacaac
     5521 tctttatact tttcttttaa tactaatact tctaatgata aatctaatct cttacactcc
     5581 catagtcttg taaatccttc agtagctcct tctttattga ttaattcttt agcagctaat
     5641 aaggctcctt tgttatttat cagttgtaaa aatcttgttg gcttatagtt acattgtaaa
     5701 tcagcttctt tatagatatt taccatgtta tggtataaat ctagctctat ttgattcata
     5761 gattttattc ccccatttta ataattgtat tttagttgaa taactctcct ttaaaagctt
     5821 tttgcattaa tgagttaaag ttgtcttcta gttcttttaa gctagtttcc atttcaaact
     5881 tcaaagagtt tacttgttta acgaagttgg caaattgatt ttgaagtcta ataggaggta
     5941 caataatatt tatttttcta acagcatctt tagttatcgt ttttgttaca gctcctctta
     6001 ctttctcttt tattttactt tccatatagg atgttagtaa aaggttatat aagaatatat
     6061 gattcacttt atcttcatta aatctaagca taaattgatt catagctaaa gatactggtt
     6121 tatttaaaaa tggcattaaa taaactttac ctgcactacc tatcttattt attataacct
     6181 caccaccaaa cacctttgat ttttcaagat aattatatgc atgttcatcg atatacttaa
     6241 cacctttttc aaagttatta ttttctaaat ctgtagttct taccattaag gcataacctt
     6301 ttgtatctaa aagagttaca ttatctctta aggtttcata actaccattt gaatgataat
     6361 cagttaaaac atctaaatat ttccctattt ctgaaatttc ccagtttttt tcattctttg
     6421 atggagtacc aaacatctca ataaatcttg atttaactaa ttcatccaat acttctattt
     6481 gctcttttct tttatctatt aactcttgag ccttgtctaa aacacgcact accttttctt
     6541 gcacttttaa attatacatg cgtattttta tattagctaa tccttcatta tttaaagctg
     6601 attgtgtagc acctttactt aacctatttt tttgatttag aaaataacta ctatttaagt
     6661 aatggtataa atattgaggc aatatttctt ttgatggttt taaaacataa aatccagtcg
     6721 atactattat atttttatta gttttattaa taactaatgt tttctttgtg tccttcattt
     6781 ttgcaaatat aacttctcct atatttacag tttgatttgc tctagaaggt ttattttcat
     6841 aagtaactat ttctagattg cttatcttgt taaaatctaa gtttccagta ctaagatatg
     6901 agcgttctcc atcaaacttt tttacatttt ccccgcttat actaacaaca tctaaaattt
     6961 ttgcttcatc aaccatactc tacacctcta acattctttc tagttcctct aatccatcca
     7021 ctatctcttt ctctaacgcc ttaaccctac ccataataac actaggagca tcataaacta
     7081 cttcttcata cactacctct ttatacttat taatagataa atcataccca ttctctctta
     7141 tctcttccac atcaacaaaa aaactttgct ctgttctttt tctatctact tcaccatcaa
     7201 gattatcaaa tctcttaata atatcctcta tatcactatc ctttatctca tttctcttat
     7261 catccaaaga ataaccatca gctttcatat catagaacca taccttatca gttccacctg
     7321 ttcctgtttt agtaaatatc attatagctg tagatactcc tgcataaggc ttaaacactc
     7381 cacttggcat tgatattata gcttccaatt tatgattatc aactatttct tttcttatcg
     7441 atttatgtcc acctgttgaa ccaaacaata ctccatctgg cactatacat gcgcatcttc
     7501 caccaatttt taaaactctt aaaaaaagtg ccaagaataa taactctgtt ttctttgtct
     7561 tagtcacttt taataaatct gctgacactg cttcataatc taaacttccc ttaaaaggag
     7621 gatttgctaa caccaatgta aacttatctt tatctgtatt aacctccgat aaagaatcct
     7681 tatactctat attaggattg tcaacgccat gcaacatcat attcatagca cctattctaa
     7741 gcatagttct atccatatca aatccataga acataccatt attaaaatgc tccttcagcc
     7801 cttgcactaa gaaaagactt gaatgattat cccttaagta ttgttgtgat gatactaaaa
     7861 aacctgctga acctgctgcc gggtctacta taatatcttc tggtgttggt ttaataagtc
     7921 ttactatcat atctattatg tgtcttggag tcctaaattg accattagta cctgctgtag
     7981 ccactttgga taataaatac tcatacaaat ctccctttgt atctctatcc ttacttaatt
     8041 ctaaattact aataccatca actattttag ataacataag aggcgtagga attttaaata
     8101 ttgcatctcc catgtacttt gcataagctg agtctttatt tccatgtaat ttttttatga
     8161 aaggaaacac ttcattttgt actatttcat acattttttc tgaatttcct tcattagaaa
     8221 acttactcca tcttaaatgt tgatgttcat cattaaatat cctttcaaaa gaaactccca
     8281 aaagagttgc ttctgcttca ttttttgttt ctacttcatc caatccttta ataaataaaa
     8341 gatatgtaaa ttgttctata acttctaatg gattagttaa tccaccagtc caaaatgtct
     8401 cccaaatctt gtctactttg ctccttaatt ctcctgtaat catatatgac tttccctcca
     8461 gtgttcataa aataatttaa atatatattt tagtcgtacg ccttaatagt tagtgtctta
     8521 tgttaaatcc aagtttttac tacacagtta ttaaattatt tttcctattt acatgtttta
     8581 gttaaaaaac taatgcaata ctcttatttt atgattatta tatataccat acaaaattat
     8641 tttatcatat atccatcata gaagtcatct acctggataa ttcttaccat attataactt
     8701 tttaatatta atttaaactt agaaagaact tttttattta attatatcat cttccttatt
     8761 tcaaatttct caattacaat attaatcaaa aaataaaata agatgctgtc tcaaaataga
     8821 tataatcttc ttttttattg tcagaatgat gaaaatatat ttaatttcat acaaaaaaga
     8881 gtgcctcatg aactaaaaag ttcattttga gacacccctt aatttaatct tacttattct
     8941 ttccctttat tattaacact tcactgtctc tattgctttt cctacacatc cacaaacttc
     9001 catcctactc ttaacaaaat ctttaactga ctctaaacct tttttaccat atttcttagg
     9061 gtcaattacc tctgggtcag aattaagcac attcttaact ccattgctat aagcaatcct
     9121 taattcagtt gcataattaa ccttgcaaat ccctcttttt atagattcct taataacttc
     9181 atctggtatt ccagacccac catgtaatac taatggaact gatacaacat ctctaatttc
     9241 agataatcta tctaaatcaa gctttggctc tcccttatat aatccatgtg ccgtacctat
     9301 tgctactgct aaagatgata cccctgttct ctctacaaac tcttttgctt ctaatgggtc
     9361 tgtatatgct cccccatcac caccatctaa atcgtcttcc ttacctccaa ctttacctaa
     9421 ttcagcttca acaggtatat ctgaaggcat acatgcatct acaacagatt tagatattga
     9481 aatattatct tcataacttt catgagaacc atcaatcata atagaagtat atccaactct
     9541 aagtgcctgc atagctagtc caaagcttga accatggtct aagtgcattg ccacaggaac
     9601 acttgccttc tctgatgcta cctttacatt cgctaaataa taatctagtc ctgcatactt
     9661 tattgttgaa ggtgttgttt gcaatattac tggtgattta agttcttcag cagcctctat
     9721 tactgccata accatctcca tattttcaac attaaatgca cctactgcat aatgcccttc
     9781 ttgtgcatct aataatattt gtttagttgt cactaatgcc ataatttctc ctcctatatg
     9841 tttatactga tttaatttct tcgttattta attttgatac tatttctcta cttgttttgc
     9901 tatttaataa ctcatttaaa aattcttcat tcattaattt tgaagatagt tgagataatg
     9961 tttttaagtg taaattatca ccattatctg tagctgctat cataaatata atatgtgcca
    10021 agcttccatc ttctgattca aagtcaaacc cttcttttga tacacctact gctacacgtg
    10081 gtacctttac tgcatctgtt tttgcatgtg gtatcgctat ccccatacca aaacctgtag
    10141 atgatatttc ttctctttta aggatttctt ctttaaactt ctttttatct aaaagaacac
    10201 cagatttatc aagtattcca atcatttcat caattacatc tgttttattt tttcccttaa
    10261 catctaaaat tactgtttct tcgctatata aagagatatt attagatacg ttttccgatt
    10321 ctgcactttc atttttatgt tcatcttttg ttgcatttgt attttctata gtatttttct
    10381 catttactac tttaggtgta accatcatat aaagtacagc acctactaat gaacctacaa
    10441 atatacaccc tacccataaa agtggcttat tgactaatcc tagaaccaaa aaccctccat
    10501 gtggagctgg tacttctatt ttcattatat aagttaaaat tgatgatatt gatgatgcaa
    10561 tcataagtac tggcaacact tttaatggat tttttgctgc aaaaggtatt gccccctctg
    10621 ttatatgagt actacctagt atataattga ttaatcctgc tgctctatct tcttctgtaa
    10681 atctattttt aaataaagta gatgctattg ctattaccaa tggtggtgtt atacaagctg
    10741 cagatacacc tgccataaat aaataatttc cctgtcctag aagcatagtt ccagttacat
    10801 atgctgcttt atttactgga cctcccatat caaatgctga catacatcct attactattc
    10861 ccaaaattat agggcttgaa ttttgtaacc ccgatagaaa gttcatcata gcattgttaa
    10921 gtgctgaaca tggcccacca agtaacaaca ttgctacacc cacaagacct acgctgacaa
    10981 taggaattat aaaaatcgat ttaagacctt ctaattgtcg tggtaatttt cttaacaaat
    11041 gtacaaatag tttaactaag taacctgcta aaaatcctga tatgattcca cctaaaaacc
    11101 ccgaacctgt atcaaatgat atcattcctc caacaagtcc tgccaacata ccagctcttc
    11161 ccgatataga ttgagctata aatgctgcca atacaggaac catcaagttc atagaatatc
    11221 caccaacaga ttttaatgta gctgctattt gattatattg ttctgaattt gggtcaaatg
    11281 aataaatccc ccataaaaat gatatagcag taagtactcc acctgctact actaaaggta
    11341 acatgtgaga tacaccattc attaagtctt tatacaactt ttgaccaaac gataagtttc
    11401 cttcttctgc aattttactg cttgataagt ttccttttct aatagctact tttccatcaa
    11461 tacatctttg tataagttca ttagctttat gtataccttc tttgacaggt acttctatta
    11521 ctggctttcc attgaatctg tccatatcaa catttttatc acaagcaact attattgcat
    11581 ctgccatttc gatatctttt gctgttaact tattttctac acctatagct ccattcgttt
    11641 caacttttat gtcacaccct aattccctgg ctgaattttt taatgcttct tctgccataa
    11701 aagtatgagc tattccagtt ggacaacctg ttacccctag aatcattttc tttcccattt
    11761 ttataccacc tttctgactc ttatattttt tatataatct tccacattct ccaaattacc
    11821 tataccatta ctttcagcca cacttgctcc tgttgctgct gaccttttta atgcttcttc
    11881 aatatgttct ggattttcca accatatact taaaaaagca gctaatgcag aatcaccagc
    11941 acatgcagag ctgactactg taactggttg agcactagca taataaattg attttccatt
    12001 ataaaaataa gaaccttttt ctcctaaagt tagcaatata ttttgagcac cttttaaatg
    12061 tagtaattta agtacatcct taatatcttc ttcatctctt acaataattc caaatatatc
    12121 tttgatttct tcatcatttg gttttatcaa atatggatta tactgtagta actcctttaa
    12181 ttttggtgaa cttatatcga gtattgtctt tatactttta tttttacaaa ttttaaatat
    12241 atcctcatag taattatcat caataccagg aggtagactt ccacttattg ataagtaact
    12301 tatatctgct aatgactgta tcttatctag catatctagt ttttgttttt catttacata
    12361 tgacccagag tttacaaatt taaattcatc acttccatca tttaaaaata tatttatacg
    12421 agttgtatct tctacccaag taggcaatac gtcaaatcct ctcttttcgc tttcttcaac
    12481 tatatatttt cctgaaaatc ctccaaaaaa tcctaatatc ttagattcta taccataatg
    12541 acctagtaca aaagttacat ttaatccctt tccattagga gaatatacag catttgatgt
    12601 acgatttact aattttctct ttatcccatt agtagatata ttcatatcta ttgcaggatt
    12661 tgtagttaat gtatatatca ttgtcttccc ccttgcttgt gctgtgtatg ttttcattat
    12721 aataaaaaag tctatgaaaa tcttttcaca aatagaaaat cgattttcat agacttttca
    12781 atttaatttt cagaattatt atatctgacc atataatcta taattatcct agatataata
    12841 tacaagggca atctggaaga tacttcatat tcagaaattg atatatgttc atgtttgtat
    12901 cctacaatat ataaatccga atactttata agttttgcac tttcactaca acagcaagtt
    12961 ataaccttag ctccaactaa attggcattc tgtgctgatt ctacaagctc tatggtattt
    13021 ccattcaatg aaaatataat tataagttca tcttttttta ttgatttaga ttttattttc
    13081 attatgttgg ggtcatttat aaaaacaaca ttaaaatcaa gtaattgcaa tttaagacta
    13141 aactcttttg ctacatattc agtaagccct cttgctaaaa tatatatctt actagattta
    13201 tttatagttt ttattatatt gattagtgta gttaaagata tttgttctat aactctctgt
    13261 gcttctataa aggatttatt tattatatcc cccatatttt gtatatcatc attttcatct
    13321 tttactgtta atctatacct aagttcattg aatccattta aaccgcattt tctaattgct
    13381 cttgaaacgg ttgctggaga tgaatatgtt tcatgagcaa tctctactat agataattct
    13441 ggtaatattg attcattttc atttataaat ttaattattt caagttccgt cttcgttaga
    13501 ttttcagaat tacttttgtt tagctcaatt atcatatgtt atctcccctt atataagttt
    13561 tatttgtcta aatttatcga gtaatataat atattacctc ttaactactt atttttatat
    13621 acaattaaga tttagtcaat gtctatatat gtaaatttat aatataataa ttttttgctt
    13681 aaagtttatt atgttatctt atagcatttt aaaataaaaa agaattgtac ctctaccaaa
    13741 atttggatga agtacaatag atattcctca tactgatatg tttatgatta aaagtataaa
    13801 tataaatttc gctatgaatc atataattaa taaatcattt tatttacaat tataaccccc
    13861 cttataaaac tatattaata atatatacag tatttataag gggggttgtt tatatttaaa
    13921 aactatttac ttttctctta attcttctcc attagttctt attacatttt gataccaata
    13981 aaaactatct tttttataac gttctttact tccatttcca ttgttatcta tatccacata
    14041 tataaatcca tatctttttt ccatttcttg agatgaacaa cttactatat ctattggcga
    14101 ccacatacaa taagctaata tttcggttcc atcagctata gcttcaccta tttgttctat
    14161 atgttttcct aaataatcta ttctgtaact atcatgaact tttccatctt caaatttatc
    14221 atgcattcca aatccatttt cagctatcat tattggcttt tggtatctat cataatattg
    14281 agataaagta ttgtataatc cttttgggtc aattgcccac ccccaaggat ttgcttttaa
    14341 atatggattc tttatattat cagttggatt catggtgttt ttacttgctg atactgttgt
    14401 agaataatag tatgataaag ctagaaaatc catagtattt tcttttaaga ttttatcatc
    14461 tccttcctct ataactatat ttatgttatt ttctttgaaa aatctcttaa tatagactgg
    14521 atactctccc ctaaaactta catcagtgaa aaaatattgt attctatttc tttttaaagc
    14581 aaacaccaca ttttcagggt cgcaatcttc tggataagat gtacaatctg ccatcatcat
    14641 ccctatcatc atatctgaat ttatttcttt tccaagcttc ttagttaaag ctgtagccat
    14701 gaattgatga tgaatagctt gatatttggc ctcttctaca tcatctacct ggtctacaca
    14761 aaatgcaact gaattaaatg attcataatg tattaaattt atttgattta taactatcca
    14821 atatttaact ttatttttat atctatttag tattaattct gcatatctaa caaagaaatc
    14881 taccactttt ctattagacc atcctttata ttttaatact aaattcaaag gagtctcata
    14941 gtgaagtagt gttacaatag gttccatacc attatctatt acttcattta taagattatc
    15001 ataaaacttt aatccctctt cattaggctc taaatcatct ccatttggaa atattctagc
    15061 ccaatttatt gaaaatctaa aacactttaa ccctagctct ttcaaaagct ttaaatcttc
    15121 tttgtatgta tgataaaagt ctattccact acgcttagga taatatccat tattatcttt
    15181 catagcaaac tttattcttt ctatagtcat atcagactca taaggtttag atatatctct
    15241 atctttatca tacatatgta catcagctaa acaccaacct ttgccacctt cattccatgc
    15301 accttctaat tgattagctg ctacagctcc tccccataaa aaacctttag gaaacttacc
    15361 caatttaatc actccttatt ttatttattt aaatcattta ctattattta ccttatattc
    15421 tatagacttt actattccta ctaaagacat agttatattt aactcgctga atatggtcat
    15481 aagagtatct tgagcatgtg caaataacag cgaatgtgct cttttctctc catcagcttc
    15541 cccttgtata atcttggttt gagctctatg tgcttctgtc ataaaccctt ttgctttagc
    15601 tagttttaaa tcagcatttc tataatcaaa cttttccaaa tcattaagag catgtttaat
    15661 ttctgttcta gcctcacctg cacgaagtat tatttgcatt gccacctcta ctaattcttc
    15721 atctattata tgttcttcaa ttgtcatatt tataatttcc tttcaatttc taaatttaaa
    15781 cctcttggct ctctaatttt atctcttctt tctcataagc tttaaaaaat ggataccata
    15841 tcataaatag caatactata tttattgcta aaacaataag acctctaaca tcttgattta
    15901 ccataaaagt agatatacca aaaggaacat accataaatt aaacacctta cttggaattg
    15961 taacaaatcc catactcatt gataaataag tagttattga tattactatt gtacctatcc
    16021 acataggtaa cattaaaaat gggttccatg ccactggagc tccaaatatt actggttcat
    16081 ttatattcat tatagaaggg acaatacatg ctcttcctat tgcttttatt cttccaactc
    16141 tggataaaca catcattata actaatggta atgtagcacc caaccctcct aaagttatcc
    16201 aacctgtttg aataacttcg taaacatata tattagttgc tactcctcct gatgctactg
    16261 ctgctgcatt agctgcaatt gcaccaagtt gaattgaata agttataggg gatagtaccc
    16321 acccacttat tcctaaagaa tatataaata ctactaaaaa gtttaagagt acaaatccag
    16381 gtaatgtctg tgctatatct gatactggtt taaatactct aactattatt tcaaacatgt
    16441 caaagttgag tccataaatt aatccccagc ctacaaacat tatcactgtt ataggtaaca
    16501 tattatcaaa ccacttgctt acaaaatccg gaagtgctga atcttctccg aaaaatgaaa
    16561 aagaaccaaa taaggacatt attaatccag agaataatcc tgcaactagc gatacaagca
    16621 ttccttctcc tccaaacctg ttgaagttaa atatagctcc ttcattcgta atctctggac
    16681 gaatcatcat taacattaat ccagcacctg caagaccagc gactacactc atactttcaa
    16741 atttcttatt cttcattatt tccataggca ataaaaatgc tataaataat cctaaaagtc
    16801 caaatgtata ttgatttatt ggacttaaat caggtaaaaa gcttatgtaa ttcttcaaga
    16861 cagaaactat agttactaat gagcctacaa ataccattgg caaaactttc attatagttg
    16921 attgaactga ttgtacccat atattcttag tcatattatt tacaacagga gtaaattttt
    16981 cacttaaaaa atctataaat ttattcataa acactctccc cataaatatt ttatttgttt
    17041 gatattagtt ctagtgcttc ttccaaagcc tttgcaccat ctagtcttcc atatgcagtt
    17101 ttagatatac atgctactgg aacgttatat tcattagcct tttgttgaat ttcttccttc
    17161 atataatcta aatgtggtcc tagtaataaa caatctattt ctgataaata cttatctatc
    17221 tctgactcac ttctcgcttt tatatctgct tctatacctt ttttctttgc actctttctc
    17281 atactagttg ccataaaacc tgtacttgct cctgaaccac acgccaaaag cactcttata
    17341 tttttcataa taatacctcc aatattttta tccattaatt tatttctt
//
LOCUS       DAEOTL010000088        16906 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEOTL010000088 DAEOTL010000000
VERSION     DAEOTL010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16906
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.088"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            133..840
                     /locus_tag="KRH82_003196"
     CDS             133..840
                     /locus_tag="KRH82_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBG8656461.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(982..1818)
                     /locus_tag="KRH82_003197"
     CDS             complement(982..1818)
                     /locus_tag="KRH82_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8656462.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENKKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            2006..2911
                     /locus_tag="KRH82_003198"
     CDS             2006..2911
                     /locus_tag="KRH82_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBG8656463.1"
                     /translation="MFFKDIELNSKKELDSYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            2920..4104
                     /locus_tag="KRH82_003199"
     CDS             2920..4104
                     /locus_tag="KRH82_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656464.1"
                     /translation="MEIRYAKEEEIESIKDIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            4219..5520
                     /locus_tag="KRH82_003200"
     CDS             4219..5520
                     /locus_tag="KRH82_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBG8656465.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTLIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            5474..6517
                     /gene="holA"
                     /locus_tag="KRH82_003201"
     CDS             5474..6517
                     /gene="holA"
                     /locus_tag="KRH82_003201"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBG8656466.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(6704..6970)
                     /gene="rpsT"
                     /locus_tag="KRH82_003202"
     CDS             complement(6704..6970)
                     /gene="rpsT"
                     /locus_tag="KRH82_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBG8656467.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            7569..8090
                     /locus_tag="KRH82_003203"
     CDS             7569..8090
                     /locus_tag="KRH82_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656468.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            8124..8900
                     /locus_tag="KRH82_003204"
     CDS             8124..8900
                     /locus_tag="KRH82_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8656469.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            9243..10196
                     /locus_tag="KRH82_003205"
     CDS             9243..10196
                     /locus_tag="KRH82_003205"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBG8656470.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            10214..11233
                     /locus_tag="KRH82_003206"
     CDS             10214..11233
                     /locus_tag="KRH82_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBG8656471.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            11264..11515
                     /locus_tag="KRH82_003207"
     CDS             11264..11515
                     /locus_tag="KRH82_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656472.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            11797..13602
                     /gene="lepA"
                     /locus_tag="KRH82_003208"
     CDS             11797..13602
                     /gene="lepA"
                     /locus_tag="KRH82_003208"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBG8656473.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDERRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            13751..15088
                     /locus_tag="KRH82_003209"
     CDS             13751..15088
                     /locus_tag="KRH82_003209"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBG8656474.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIHCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEAIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVGLFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            15321..16634
                     /locus_tag="KRH82_003210"
     CDS             15321..16634
                     /locus_tag="KRH82_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8656475.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
BASE COUNT         6664 a         1769 c         2800 g         5673 t
ORIGIN      
        1 ttaattaaaa gatacctttt taaatttatt ttaagataat ttatttttaa taatatataa
       61 tgttttgtat tatataatgt aaattttcta atactattat atatttagat aaaaatctag
      121 gagtgtggaa agatggaaaa taattttaca acgagaacta gttttctagt tggagatgat
      181 gggataaaaa aacttaataa ttcaaatata atagtatttg gagttggagg agttggtagt
      241 tttactgttg aagctttagc aagagctgga gtaggcaata ttactattgt agattttgat
      301 gatgtagata taaccaatat aaatagacaa ataccagccc tacattcaac tgtaggaaga
      361 tacaaagttg atgtcatgga agaaagaata ttagatataa atcctaatat caatataaaa
      421 aaaataagga gtctttataa taaagatact agtgacgaaa tactaactga aagatatgat
      481 tatgttgtgg atgcgataga catggtaagt tccaaaatac atctaattga aacttgtgaa
      541 aaaaaaggat tgaaaataat aagttctatg ggtatgggaa ataaattaga cccaactaaa
      601 atagtcgtta cagatataca caaaacaagt acttgtcctc tagctaaagt tatgaggaaa
      661 gaacttaggg atagaggtat caaaaagtta aaagtagtat attctactga acaaccaata
      721 gaacttaaga agaaagtaat gaatggtaga aaagtaacac ctggtagtgt atcatttgtc
      781 ccatctgtag gaggtttaat aatcgcatct gtaatagtaa atgaactatt aggacaataa
      841 gttttaaata ttttaattta taaattttat atacaaattt gaaggctaga agcatgaata
      901 caaagcaatt ttatattcat acttttagcc taattatttt atattacctt attttatgta
      961 gttgtagttt tattttttag attatgtatc tatttcataa ttatattttg taaatataat
     1021 ttctccatca ctataaaaaa caatatctcc tattctatct gttctataaa ttgatacatg
     1081 gttttgtttt agattattaa taacctccct atgtggatga ccatattgat ttttatatcc
     1141 acatgatatt gcagctatat ctggactaat tttttttata aattctaaag atgaagaaga
     1201 attacttcca tgatgaccta tttttataaa attaatatta tttaatttaa aagaatgtaa
     1261 aatttctttt ttattttctt cttcagcatc acccataaat aaaaaagaat tatcattaaa
     1321 agttaattta aaaactatag aatttaaatt agattcttct tgtatatatg atggacttaa
     1381 tacatatata tttatattgt tatctatgtt taaaacatca tttttataga gatgctgaat
     1441 agataagttt ttatccgtac aagaatttat tagattttga taagcctcac tatcagttga
     1501 ttgttcaggc atatatatgg agtttacatt aaattttttt ataatattat caagacttcc
     1561 tatgtggtct gaatctggat gagttgctat tataatatca atagttttta ttcttttttg
     1621 tctaagataa ctaataatta tattttcgct atcttcatca cctccatcaa ttaatatatt
     1681 cttatttgtg ggtgtttgaa ctaaaatact atcaccttgt ccaacatcaa tcatatgtat
     1741 agatagtaga gattttttgt cacagccgat taaaagtgat attataataa gtattgataa
     1801 aaaaatttta tttctcaata aaaaatcact ccattcatta catgtttata taaatttatg
     1861 atgggtaata taagatatat atgacttatt atattttata ttttaaacaa tataaatgaa
     1921 attaatacca taataaaatt ggagtttttt atatatacaa aataaaattt ttaaaattaa
     1981 gcaataaaaa aggtaggagg attttatgtt tttcaaagat attgaactaa attcaaaaaa
     2041 agagttagac tcatattttg atttagtaga ttatgaagct tgtgagtact gttttagtac
     2101 tttatatatg tggcaacatg tttataagac aggatattat ataggtgaag attttgccgt
     2161 tttagttggg gaatacgaag gagatagctt ctcaatatta ccacttgcta aaaaagataa
     2221 acttccagaa gttgtagatt ttgtccttga atatttttct aaaaataata aaaaaatata
     2281 cttaagaggt attactactg aagtagtaga gtttttaaaa gaaaaatatc caggtagatt
     2341 tgagtatata gaagaaagag atttatttga ctatatttat gatgcagaaa gtttaagaac
     2401 tctagctggt aaaaagaatc aaaagaagag aaaccatata aactatttct taaaagagta
     2461 tgcaggtaga tatgaagcta aattattaga taaagaaaac tttgatgagt gtttagtact
     2521 aatgaaggaa tgggaaagta ataaggaaga aaataatgaa tttgatgaaa gtatggatga
     2581 tgaattaata ggtatcaaaa agatatttaa ccattatgac atattaaaag ataaggtaaa
     2641 agtgtttggt gtttatgtag atggaaaatt agaagctttt agtataggag agcttttaaa
     2701 tccaaatatg gcattgattc atatagaaaa agctaatccc gatataagag gtctgtatcc
     2761 atttataaat caacaatttt tggtaagtga atttaaggac gttgagtttg taaatagaga
     2821 agaagattta ggtattgaag gattaagaaa agctaaactt tcttatcatc cttgcagatt
     2881 tgttgaaaag tacagtgtta gggaggctta atagactata tggagattag gtatgctaaa
     2941 gaagaagaga tagaaagtat aaaagatatt tggagttatt gttttaacga tacggagagt
     3001 tttatgaagt actattttaa tgataaatat aaatctgaaa atactgtagt agctttagat
     3061 gaaggaaaaa ttatttcttc tcttcagcta aatcagtata agttattact aaatagcaag
     3121 gtatataata catcatatgt ggtaggagtt tctacacttc cagagggaag aggagctgga
     3181 tatatgaaca aagtaatgaa atttacttta aacgaattgt ataaaaaagg gcaattagtt
     3241 tctatattga tgcctattga ctatagactt tatagaagat ttggatatga gcattgttac
     3301 gaccagattg aatatactat taacacagat gatttaaaaa attttaagtc aagtggaaaa
     3361 atgataaagt ctaatttatc acaaattgat gatttgatac aaatagatag aactttttta
     3421 aatgaggtta atggtaatgt gttaaaagat gaacattatt atgaaaactt atttaaagag
     3481 attcaaagtg aagatggatt tttatacatt catgaaggaa atgaaaaaga tggatatata
     3541 gtttattttc ttcaggaaga taaaatgttt gtcagagagt tattttataa aaatatagat
     3601 gcccttaaat caatgcttaa atttatatat aatcacaata ctcaatgtaa gatagttact
     3661 atatctactc ctacaataga taagataagg tttatattag acaaccctaa agatagtgat
     3721 ataaaaataa aaccttttat gatgggaaga gttataaatg taaagaagtt tattgaagat
     3781 atagatattg agaatgatat taatagctca tttaatttat taatagaaga caagtttata
     3841 gatgaaaata atggtctatt taaaatttct atacagaata agaaggtatc tgtagagcag
     3901 ttagataaaa aaggtgcaga aaagcctcaa gaagattttg atattaaatt agatataaat
     3961 accttaacac agttatcatt ttcttatata gatgtaaatg aagctatttt cttaaatgat
     4021 ataaaagatg tttcagaaga aacactagaa acacttaatt gtattttttc taaaaaaaat
     4081 aactatataa atgaatatat ataggtagag tacgttaaaa gattttaaaa atcttttgac
     4141 gtattttttt gtttagataa caatttatct tgtttaaaaa ttttctattt gaaaataatc
     4201 taaataatat acttttatat gggagtgatt ataattcaaa taagaagacc attattaatt
     4261 atattaatgt ttgtggtagc tatatcattt atcattacaa ataacacaaa aaacgacgaa
     4321 gaacttaatg ataagataat aactatacaa ggagttgtca aaggaaaaat tgaaaagaaa
     4381 agatacaatc agtacaaggt aggggttttt ctaataaatg attatacaaa aaataaaaat
     4441 ttgaagattg gtcagaaagt taatattaca ggtaaattca aaagtttaga taaaatgaag
     4501 tatgatgatt ttgattatgg aaggtatata aaaagtactg gatataaagg tatagtgtat
     4561 ataaataact ataaaattat tgataaaaat aaactttact ctttaatagg ggaaataaag
     4621 ttttatatta gtaaaactta taggtactta tataagaaaa actcagattt tataaattct
     4681 atactattag cagaagttga aaatttgact gaggaacaaa aagaaatttt taccagaact
     4741 ggaactagtc atgtaatatc tatatcaggt cttcatacag gaatattatg tgtaattata
     4801 tcctttctat taagaggtat aaataaattg tataaattat taatactgtc gatttttata
     4861 actttatatt gtataatggt aggtgcgtct ccatccataa ttaggtctat agcatttgtt
     4921 atgatttttt atttatcaat atttattgat agaaagaaag atggaatatc ggcattgtct
     4981 ctaattggga taattttaat tatgaataac ccctatgtta tatataatgt aagttttcaa
     5041 ttgtcttttt tagctacact ttctatatta atattctata ataaaataaa tagtattata
     5101 aaattaagta tggtatcatt gacaatatca tcaaatatat taactttacc tataatttat
     5161 tatacattta aaggtatacc attgctttca attataggaa atttaattat agtaccattt
     5221 gtgggagtaa taatgtattt aagtattgca agtttaatcg tatttaaagt aagtgtagta
     5281 atagctaaaa ttatatcttt ttttaatagt acattgatag aaagcatatt ttttttacta
     5341 gaaaaaatca gcaatttaag ttttgcatac attaatatag aaaatcctaa attttatatt
     5401 gttgttattt attacatagg agtgtttttt tacatatttt acatagaagg aaaagagata
     5461 aaggagcaag agaatgaatt acaaggatat tataaggaat gtaaaagaga aaaactttga
     5521 aaaaatgtat cttttttatg gaagagagta ttatttaatt gagaatgcaa taaaagcatt
     5581 taaagatagt ctaaacgagg gaatgcttga ttttaattta gatataatag atgggaagga
     5641 aatagtctta aatcagctta taagctctat agaaacactt ccatttatgg atgataggaa
     5701 gatagtaata ataaaagact ttgaactatt aaaaggaaag aaaaagaatt ttacagatag
     5761 tgatgagaaa tacttaatag agcatttaga caatattcca gacaccacaa ctatagtttt
     5821 tgttgtatat ggagatgtag acaaaagaaa atcattagtt aagaaaatag gaaacaatgg
     5881 aattgttttt gattgtgata agctttctga tatggatttg tttaaatgga taaaaaaatc
     5941 ttttgcttta aatgatgtta taatagataa ttctcaaatc atgtatttta ttgaacaaga
     6001 aggatacaga gataagagta gtgaaaaaac attatctgat ttagaaaatg aaataaataa
     6061 aataagttca tttgttggta aagggaataa tgtaaccaat gatgtaattg ataaattatc
     6121 tcaaaaaaaa gttgagaatg atatattcaa attaatcgat tatattggag aacaaaatgc
     6181 ttctaatgca atgaaaatat taaatgatat gatacaagaa ggcgaatctg tattaggtat
     6241 attttctatg atagcaagac aatttaaaat aattatgcaa gtaagacagt tacaacttga
     6301 tggatattca acaaaactta tagctgataa attaaaaatg catcaatttg ttgtaggaaa
     6361 agcattaaag caaactaaaa atttttctga tgatataatt gtggaaatat taaactatat
     6421 attagaaagt gattacaaaa taaagacagg tcttataaga gatactttag cagttgaaat
     6481 gttggttagt agatactgta aaagagaagc aatttaaaaa atctatatat taataaaaaa
     6541 taaatagcaa gatatgttat agttcagagt agatgtaagc taaattaagt ttgatataca
     6601 atcaactata atatgtctaa ctatttattt tttattgtat aaatttacaa aataaaaaac
     6661 ccctacatag gggttattat atataagaaa tataaactgg taattaagcg ttcataccgt
     6721 ttaatttttg agctaattta gctacttttc tagctgcagc attcttatgt atagttcctt
     6781 tagaagctac ttggtatatt cttttttgag cgtattggaa cttagcaaca gcatcctctc
     6841 tgtttccagc tgcaacagca tcttcgaatc ttcttattgc agtttttatt tgagattttc
     6901 taactctatt taaagcagtt ttcttttcga taacacttat tcttttctta gctgatttta
     6961 tatttgccac cgtgttcacc tccctgtatt tttttatcat attcatcgtc aacatattag
     7021 attttaacag aaataaatct aaaaatcaag gattattatt tatatatttt aataatgttt
     7081 tttattttga ttttttagac tgtaaattgt gtataaataa tttgcaatat cttgttttta
     7141 aattggtata ttttgtgttt taaatatttt gacatatata aattaatatt ttatttttga
     7201 aacaaatatt ttgagataat acaaactatt aacatacatt ttgatagtat ttccaataat
     7261 tataagataa tacaagaaat tactcatttt tgtaaattta atgaaaaatt ataaaaatat
     7321 aaatttatat gcttaattaa gataattttt ccaataatca agataatttt tttcattagt
     7381 atgtatgata gatgcatcaa acaatataac taatatgtta gaaggttata tgtaattaat
     7441 ctcagtgttt atatagaata gcatttgtag catttattat agttgtaatt actacttata
     7501 tcatagactt gaatagtcta aaaaaataga ctataatatt tttatagact aaagaaaggg
     7561 ctgataagat ggacatagca aaactaattt taaatcctgc aaggcttcgt atcttacaat
     7621 atattcgact tcatggcagt gttcgtacat ctgatattgt aaagtattta aatgatattc
     7681 ctcgtgcaac agtttatcac catgtaaaaa ttttagaaga gaacaatatg attgaagtaa
     7741 ttaaagaaaa tcgtgtgcgt ggtactattg aaaaggttta tgcactaaag gaatatacaa
     7801 catctatgga aggagagacc ttcgttgcac tttctacagc attttatgta ggtctgatgc
     7861 aggaaatgaa tgaatacttt agcagaaaag agcaagacca taaaaaggat aatgtatttt
     7921 tctcttcagc attactatat atgagtgata atgaatatga aaatcttctt aaaagtatag
     7981 ctgatttatt gaaaccatat atagaacaaa agcctaaatc aaatctaaaa cttagaaaac
     8041 tttcaattat atcttctcca cctgtagctg ataatgataa aacaaaataa catgcaaccc
     8101 atttttataa aaggaggtta tatatgaaat ttcatgagtt tggaaataaa aacagaccac
     8161 atattatgtt gattcatggg ggagggaatg catggtggaa ctatttgcga caagcagaag
     8221 ttttgtctaa caaatatcat gtgatacttc ctacattgga tggtcatgga gaagaatatg
     8281 aaacaacata catttctaca gaggatacag cagataagtt gatatcatat atagatgaaa
     8341 attgcagtgg acatcttttc gctttgtgtg gggtatcact tggtggtcaa attgtcatgg
     8401 aacttttatc tcgaaaacct aatattacta aaaaagcaat tattgatggt agtatttgct
     8461 acccaagacc tcttatggca aggttttgta ttgctggtat tcgatttttt ggaggacttt
     8521 tgtttagtga gaaggcttgt cgctttcaaa ttgctatgat gccaaaattg ttacctgaaa
     8581 atatgcaata tccagatgaa ataaaagcat attatatgac agatatgcca catgtaagaa
     8641 aagaaacatt ctataatatg tatcgtactt atatgatgaa ctatacactt aaagagaatg
     8701 ttaaaaaaac cacagcacaa gtaatgtact ggtatggaga aaaagaaatg aagtgtgtca
     8761 aaaaatctgc aaaactgttt cagtcttatg tgccctcttg tgagatttat gaagctaaga
     8821 gctataatca tgggtattta tcactttatc ttccaaatga atggttggaa attgcagaac
     8881 catttttcca aaaggaataa aggtgttagg tgattattgt ataattattg ctgtttttta
     8941 atatagtaaa taaattaggt ataaatataa aaaagttatt ttagttaata tattagtgaa
     9001 agcttaatag gaaaattata aatagattaa aggtagcgcc tatataaata gttgctacct
     9061 ttttctgttt gtaaataaat gatagataag aaggtttact gacaaatcac tgactaaacc
     9121 caattttctt acattgaaag ccttaatttt acttgtttta aataaattta caatttcttg
     9181 ttataaaata ctaaattttg ttaacaatta taattagcat ttaatttata ctggaggttt
     9241 atatgattag tgtaagaaca gatttagctt tagaagctag tgaaatgtgt gaaaagtctc
     9301 aagaaggaag tagtattcct ggtgtaaaaa tagaaactaa agaattagaa aattgcattg
     9361 taactaaagt tgaagtaata gacaggcaag gcgcagagat aatgaataaa gatataggaa
     9421 agtatataac tctggaaagt aatcttatga agtttgatga tgatgagtca agagaagaaa
     9481 tgataagtta tttaaaagag gagttagtag atatatttgg ccaagacaaa aataaaaaaa
     9541 ccctggtaat tggtcttgga aatagaaata ttacttctga tgcgttagga ccaaagagtg
     9601 tatcaaaaac acttgtaact agacatcttt ttaaaaatta taataaagac tatgatgatg
     9661 atttcactga ggtatcagct ttaagcccag gagttatggg tgttactgga atagaaacta
     9721 gtgaaatagt aaaatcattg gttgagaagg ttaagccaga tagagtagta gcaatagatg
     9781 cattggcttc aagaaaaatg gagagagtaa actctactat acagatatca acagcaggaa
     9841 tatcacctgg tggaggtgtt ggcaatacta gaaaatctct aactaaagaa actttaggcg
     9901 tggatgttat tgcaataggc gttccaacgg tagttgatgc agcaactctt acaatagatg
     9961 tcttagatat ggcaatagac aatttaatag ctcaatcaga agaaacagaa agtttttatg
    10021 aaatgttgaa aaaacttaaa gaagaagaaa aatatcatct aataaaagat tcgttagacc
    10081 catatgacaa gaacttaata gtaacaccaa aggatataga tgatacaatc gaaaatctat
    10141 ctataataat aagtgaaggc ttaaataggt ctttacatcc aggtagattg gtataaaata
    10201 aggaggagca attatgttta aaaaatgcat taaagtagta accttgactt ttatattagt
    10261 atgcatttta ccaggaaaat cattagcttt gaatcaagat gattttttaa agtttttagt
    10321 aaattcatct tatccagaag ctaaagtcga aggaaatgat acagaaaata aaaagaataa
    10381 taaaaataaa gaaacaagta aggaaaataa ggaagaaagt aaagaagaaa acactaaatc
    10441 taaagatgca agtaaagtcg ataataaaaa agagagtgaa aaagaatata taaaacttta
    10501 tgttggtaaa gaaaatgttc cagatattga gtcaaaaaat tcagacacaa ctgaaactaa
    10561 cacaacatct agttcagatt ataaggatga tttaagagta accaaagaaa atccaagaat
    10621 tttgatatat catactcatg gatgtgagac ttattcaaat tcacctgatg gaaattatca
    10681 ttcaagagat aagaaaaatt cagtaatgga agtaggaagt gcattaacta gtgctttaga
    10741 tagcaaagga tggggtgtag tccatactac taaataccat gactatccat cttataataa
    10801 ctcttatgca agtagcttaa aaacaataca aagtatatta cctaaatata actcagtgga
    10861 tatagcgata gacttacata gagatgctag ggatttaact aatccagcca ctaaggaaaa
    10921 agaccattta aaatatacaa ctatgataaa tggagagaga gtatcaaagt tcttctttgt
    10981 tgtaggaggt aaaaatacaa atagaaaaca acttagagct ttagcagaag atataactgc
    11041 ttttgctgag aaaaagtatc ctggtctagt atctccaata gtagaaaaag actatgctag
    11101 attcaatcag tttgcagtta agaatcatat gttagtagaa atagggaata acgcaacaag
    11161 tgtagaagaa tctaaggcta ctacaaagta tttagccgag attttggatg aatattttaa
    11221 acaaaaaaat tagagcttta agttataatt aggagcatgc taaatgagcc gattagaaaa
    11281 aaatatagaa agtaaaagta aactaagaaa atacaagtat attatgagaa tcttattttt
    11341 gattactatg attatatgta catcagtttg tgtatttata gtggacagta atgcaaaaag
    11401 tatgctagga atgaaacaat atgattttcc aagtattaaa tttgatataa caaaatttga
    11461 ttttgacata ccaaattttg atatacatga aatcataaaa aaatttaata agtagtaata
    11521 agtgaataag gtttattgat taaaataagc cttattttag ttatatattt ttaatgtata
    11581 aaataaaaat tcattaactg tattttatag gatttacttt aagtttacga tattatataa
    11641 tatttagtgt tagacttgat aatccacata taatgtggat aattttgttt agtgccaatt
    11701 agtttatatt caaaaatttt aaatttggta tataaagagt ttttagataa tgtaaaataa
    11761 taactataag aataatcaag aggagggaat tttaaggtgg acaataaaca aagtagaact
    11821 agaaatttta gtataattgc acatatagac catggaaagt ctaccttagc tgatagatta
    11881 atacaacaaa ctgggcttgt tagtgaaaga gacatgaaaa gtcaattact tgacaatatg
    11941 gaccttgaaa gagaaagagg aatcactata aagcttcaaa acataagatt aatgtataaa
    12001 gcgaaggatg gaaatgaata ttatttaaat cttatagata cacctggaca tgtagacttt
    12061 aactatgagg tatcaagaag tttagctgca tgtgaaggag cactattagt agttgatgca
    12121 gctcaaggtg ttgaggcaca aactttagcc aatgtttatc ttgctataga ccaagattta
    12181 gaaatattac caataataaa taaaatagat ttaccaagtg caagaccaga ggaagtaaaa
    12241 aatgaaatag aagatttaat agggcttgat tcaagtgaag ctcctcttat ttcagctaaa
    12301 actggtttaa acatagaaga tgttttagaa gatattgtaa aaaatgttcc tccacctaaa
    12361 ggagataatg aagctccatt aaaggcatta atattcgatt cttactatga tgcttacaaa
    12421 ggtgttgtag cttatgttag agtatttgaa ggaactgtta aaaagggtat gacaataaaa
    12481 atgatgaata ccaataaaaa gtttgaggta actgaagttg gtgtcatggc tccaggtcaa
    12541 actgaactta gtgaattatc agcaggtgat gttggttata ttgctgctag tataaaagat
    12601 ataagaagtt gtcgtgttgg tgatacaata acagattcaa ataatcctac agaagaacct
    12661 ttaccaggat acaaaaaagc tactccaatg gtatattgtg gtatatatcc aggagaagga
    12721 gaaaagtatg agaatgttag agatgctctt gaaaagcttc aagtaaatga tgctgcactt
    12781 gaatatgaag ctgagacttc agcagcacta ggatttggtt ttagatgtgg tttcttaggt
    12841 cttttacata tggagataat gcaagaaaga cttgagagag aatttaacct tgatataatt
    12901 actacagctc catctgttat atatagagtt acaaaaatgg atggagaggt tgtaatgata
    12961 caaaatcctg caaacttacc agaaccatct gagataaaga tgatagaaga gcctatagta
    13021 aaaggagata taatagttcc taaagactat gtgggtgttg ttatggagct ttgccaggaa
    13081 agacgtggaa atatgttaaa tatggaatat atagatgaga gaagagtaat gcttcactat
    13141 gaccttcctc tcaatgaagt tgtttacgat ttctttgatg ctttaaaatc gagaactaga
    13201 ggttatggtt ctcttgatta tgaggttaaa ggttatgtag catctacact tgtaaaactt
    13261 gatatattaa tcaataaaga gcaagtggat gcacttagtt ttattgtcca tgagacacgt
    13321 gctttcccta gaggaaaggc aatgtgtgag aaattaaaag gagaaattcc aagacatcag
    13381 tttgctatac caatacaagc tgctgttggt aataaggtta ttgcaagaga aacaataagt
    13441 gctctaagaa aagatgttct tgctaaatgt tatggtggag atatatctcg taagaagaaa
    13501 cttcttgaaa aacaaaaaga aggtaagaag cgtatgagac aaattggttc tgttgaagtt
    13561 cctcaaaaag catttatgtc tgtgcttaaa ttagatgagt aaatccttat aaatttagat
    13621 aaagatattt aaaagctaga gtgattttag aattatttct aaattagtct agctttttta
    13681 tggtatattt taagtaaact catagagaat ataagtaaga atattaaaga agaataaaaa
    13741 ggtgatattt atgattaata tagaaattcc taaaaaagta gactatataa ttaaagaatt
    13801 agaaaagaat ggttatgaag cttatatagt tggaggatgt gttagagatt gtttattaga
    13861 aagagttcca aacgattggg atataacaac tagtgctaga ccagaagtgg tagtagaatt
    13921 atttgaaaaa acaattccaa ctggtataca acatgggact gtaacagtta tgattgaaca
    13981 tgaaccattt gaagtgacaa cttatagaat tgatggaaat tatagtgatg gtagacatcc
    14041 agattcaata gaatttacaa ataacatagt taaggacttg tcaagaagag attttactat
    14101 caattcaatt gcatacaatt caaagacagg attagtcgac ccatttaatg gctatgaaga
    14161 tatacaaaat aagtatatac attgtgttgg aaatccagta gatagatttg aagaagatgc
    14221 acttagaatg cttagagcag ttagattttc agcacaactc aattttaaaa tagctgaagg
    14281 tactaagcaa agtattcata aaaaagcaga tttgataaaa aatgtttcta ttgaaagaat
    14341 ccagacagag tttaataaaa tattagtatc tgattcatct aaattaaact tattaaaatc
    14401 aacaggtttg ttgaaattta taattcctga aatatgtgaa ttagaagatg ttactcaaca
    14461 caatccatat cacatctatg atgtacaaaa acatacttta atagctacag aagcaattga
    14521 agatgaactg tatttaaaac ttacaatgtt gtttcatgat ttaggtaaaa aagtaactaa
    14581 aacaactgat aaaaatggtg ttgaccattt ttatactcat agtagagaat ctgtaaagat
    14641 tgcaaagaag attttgaaaa gacttaagta tgataattat actattaata aagttttaat
    14701 attaatacaa tatcatgatt atagaataga acctaaaagg aagataatta aaaagttatt
    14761 aaataaactt gaagatgttg gattatttga agatttaata aaagttaatt gggctgatac
    14821 acttgcaaaa aatccaaagt atgcaaaaca aaagatatta aatcttattg agtgtgaaaa
    14881 agaatttaaa catataataa atcaaaagga gtgctttaat cttaaagatt tagctattaa
    14941 tggaaaagat ttgatatcta taggtataaa accaggtaaa gatataggat atattttaaa
    15001 taagatgctt gaaatagtca taaataatcc agagttaaat gaaaaagaaa tactaaaaga
    15061 aaaagcatta aatatatata cattttagat tcaaatataa aaaatttaat tactttaaaa
    15121 aacatagaat aaaatactta tttagataaa ataaataatt tttagagaat attttagaag
    15181 ttacgattgt atgattttta aatgcatagg catttactct aggactatag actaatataa
    15241 aaaaaaactt tgggaatact aaaaccataa atttataaaa ttaatatttt atatactgta
    15301 aaacagtgag gagggacagt atgcatactc aactacaaaa gactattggt ctttcagcag
    15361 ctctttctac tgttgtaggt atggttatag gttcgggagt tttttttaag ccacaagcaa
    15421 tatacactac aactaatgga gctccaggtc taggtattat agcgtggctt ttaggtggtt
    15481 ttataacaat aactgctggg cttacagcta cagaaatttc agctgctata ccaaaaactg
    15541 gtggtatgat gatttatatc gaagaaatat atggagaaaa gttaggtttt ttaactggat
    15601 ggatgcaaac tgtattattt ttcccaggta catcagcggc attaggagta atatttgctc
    15661 aacaagcatc tgaactttta ggaatgagcc caaataatat ggcaaatgta cttcctatag
    15721 caattggagt tatactattt ttagcgttat taaatataat aggttcatcc ttaggaggaa
    15781 aagttcagac agtagccact attggaaaga tgataccttt aattttaata atagtctttg
    15841 gatttattaa aggtcaaagt agtgaagtat taaatccatt tgtaggagat ggtgtaaatg
    15901 catcaaatgc acttggacaa gtattaatag ctactttgtt tgcatatgat ggttggataa
    15961 atgttggagc tatatcagga gaaatgaagt ctccagagaa agatttacca agagcaatag
    16021 ttggtggttt atcattagtt atggcagttt atattataat aaatatagct tatctttggg
    16081 tagtaccagc aagtgaatta gcaacagtta cttccccagc tacattagta gcaacaagat
    16141 tgtttggaaa tataggtgga aaagtaataa ctgtgggtat attaatatca gtatttggga
    16201 cattgaatgg atatttatta acaggttcaa ggatacctta tacattagct gaaatgggaa
    16261 ctttaccagc atctaaaact cttttaaaag taaattctgg aggttctcct gtaaattcaa
    16321 tactacttat aactgtgtta gcctgtgtat atgcattatc tggtcaattt aatcttttga
    16381 cagacttaac aatattttca atatgggtat tttatgtatt gacttttata ggtgttatga
    16441 ggcttagaag acaaaagcca gatttacaca gaccatataa agtcccttta tatccaataa
    16501 taccaattat agctatatta ggtggactgt ttgtaataat aaatcaaata ttgacttcaa
    16561 cagtcatatc tttaggcgga atatttataa cactattagg tttaccagtt tattattata
    16621 tgaaaaaaag ataactactt aatttaagtt agataaattt gggtaaaggt gaaaattaac
    16681 ttttatccaa attttttata ctgttataca atataagtat tatatattgc ttgatgtgct
    16741 attttgtttg atttataatt tagtaattga tgttttaaga taatttaaga aatgaggagt
    16801 gaaagatgct aggactttat gtacatattc cattttgtgt gaaaaaatgt aagtattgtg
    16861 attttaattc ttataaaatg gacatagatt caaaaaaaag atatat
//
LOCUS       DAEOTL010000089        16694 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEOTL010000089 DAEOTL010000000
VERSION     DAEOTL010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16694
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.089"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            172..840
                     /locus_tag="KRH82_003211"
     CDS             172..840
                     /locus_tag="KRH82_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656476.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            842..1327
                     /locus_tag="KRH82_003212"
     CDS             842..1327
                     /locus_tag="KRH82_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBG8656477.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1388..2509
                     /locus_tag="KRH82_003213"
     CDS             1388..2509
                     /locus_tag="KRH82_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBG8656478.1"
                     /translation="METNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGIAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTAVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2790..3980
                     /locus_tag="KRH82_003214"
     CDS             2790..3980
                     /locus_tag="KRH82_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8656479.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4114..4369
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4428..5429
                     /locus_tag="KRH82_003215"
     CDS             4428..5429
                     /locus_tag="KRH82_003215"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBG8656480.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5533..5922
                     /locus_tag="KRH82_003216"
     CDS             5533..5922
                     /locus_tag="KRH82_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBG8656481.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVITKKDKHSNIIENVEFSIKDEEE"
     gene            6083..7291
                     /locus_tag="KRH82_003217"
     CDS             6083..7291
                     /locus_tag="KRH82_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBG8656482.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7377..8453)
                     /locus_tag="KRH82_003218"
     CDS             complement(7377..8453)
                     /locus_tag="KRH82_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBG8656483.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8682..9209
                     /gene="hpt"
                     /locus_tag="KRH82_003219"
     CDS             8682..9209
                     /gene="hpt"
                     /locus_tag="KRH82_003219"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBG8656484.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9298..10230
                     /locus_tag="KRH82_003220"
     CDS             9298..10230
                     /locus_tag="KRH82_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBG8656485.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIAAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNMSD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10292..11518
                     /locus_tag="KRH82_003221"
     CDS             10292..11518
                     /locus_tag="KRH82_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBG8656486.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTRFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11602..11823
                     /locus_tag="KRH82_003222"
     CDS             11602..11823
                     /locus_tag="KRH82_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBG8656487.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            12012..12182
                     /locus_tag="KRH82_003223"
     CDS             12012..12182
                     /locus_tag="KRH82_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656488.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(12275..12736)
                     /locus_tag="KRH82_003224"
     CDS             complement(12275..12736)
                     /locus_tag="KRH82_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656489.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILRKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            12919..13386
                     /locus_tag="KRH82_003225"
     CDS             12919..13386
                     /locus_tag="KRH82_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656490.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            13429..15192
                     /locus_tag="KRH82_003226"
     CDS             13429..15192
                     /locus_tag="KRH82_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBG8656491.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            15200..15808
                     /locus_tag="KRH82_003227"
     CDS             15200..15808
                     /locus_tag="KRH82_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8656492.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            15880..16449
                     /locus_tag="KRH82_003228"
     CDS             15880..16449
                     /locus_tag="KRH82_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBG8656493.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         6540 a         1686 c         2935 g         5533 t
ORIGIN      
        1 atattatatt tttaaacttg aaaagtaagt aattataagc tatttaatca ctggaataaa
       61 tttacaataa aaaaataaat acaaaggctt tatcattaag gtattggcat aagttttgct
      121 tattaaacaa gtatactaat aaaattcatt taaacaggag ggagaattta tatgagtaaa
      181 ttagaatcaa caacagaaaa agttgaggta aaatggtatg ggtatgtagc attaatattg
      241 ggagcattat ttttttcagg aatatttaaa gatgcaccag gaccattaaa agtattggat
      301 tttaacaatg tattaggttc ttttggaaca ttgggaacaa ttaatgatgg tgtaggtaca
      361 ttagctgcaa actttagagg tgatggaggt actggccctc gagatggatg gctatatgca
      421 ttgacattaa taccatcagt tatgtttgca cttggagtag ttagagttat agaccactta
      481 gatggaatga aggcagctca aaagcttctt agtccactat taaagccatt attagggtta
      541 cctggatttg caggactaac tttgatagct agtttacagt ctacagatgc agctgcatct
      601 atgactaaag aacttaaaga tgatgggtat atagatgaaa aacaaaaagc tgtattttgt
      661 gcatttcaat tttcaggtgc gtctgcaatt acgaatttct ttgcttctgg agcagcacta
      721 tttccattta taggagatgt accaatattt ataccacttg ctttaatatt aattatgaag
      781 tttgttgggg cgaacttact tagattatat ttaaataaat ttgacaaggg ggaagcttaa
      841 catgagtgag gtagcaaaaa aagaagtaaa agttaaaaaa ggaaatgtga tagatgcgtt
      901 tattggagga gctagaaatg gattccaaat aagtacaaat tcaatggctc caaatgtcat
      961 cttcggtttt gctataattt ctgtgttcaa tttaacaggt cttttggatg taatagggac
     1021 aatatttaca cctgtaatga gtatctttgg acttccaggt gttgcagcaa cagctataat
     1081 gacaatattt atatcaatgg gaggagcatc tggagtaatc gcaggtttat ttacagcagg
     1141 tcaaataagt caagcacatg ttgcaattct attgccaatg ttattgcttt caggagcgca
     1201 gatacaattt atggggagac ttttaggaac agctgagtta aaaactaaat attatccaca
     1261 tatgtttgtt atagcaactt taaatggttg tattgcaatg cttataatga attatttcgt
     1321 agtataggta attataataa agatttaata taaatggaaa gtttaaattt taaggaggag
     1381 ctagattatg gaaactaaca aagactatat tgagtatgta cataaagtgt atgattatct
     1441 acacactata ccagaaaaag gatttgaaga atataagaca tcagagtttg ttttaaaaga
     1501 gcttgaaaaa atggggtttg aaaatattaa taaaggaatt gcaggaactg gtattatagt
     1561 aactatagat tctaaaaaag aaggaccagt atttgctata agagcagata tggatgcatt
     1621 ggaatttatc atagatggag aaaagaaaat gatacatgct tgtggtcatg atggtcatac
     1681 ttctatgctt ttaacagctg caaagttaat aaaagagaga aatttagtaa aaagaggtaa
     1741 gttaaaaata ctttttcaac caggtgaaga aaaattatat ggagcattaa gagtaattga
     1801 ttctggtttg ttggatgatg tagaagaaat ggtagggatg catttaagac ctggacaaga
     1861 ttgtaggttg ggaaaggcga tacctgcaat gtaccattgt gctagctgta taatggaatt
     1921 tacgattaaa ggtatcactt gtcatggttc taaaccacat ttaggagtaa atgcagtaga
     1981 tgctgtctgt ttagcagtga atgcaataaa tgcaataaga gtaaatccag ctataccaaa
     2041 ttctataaaa gtaacaaata tatcagttaa gggagaaact tataataata taccagatga
     2101 agcatttatg gctttagata taagggcaga aagtaatgat ataatagaag aattaaaaga
     2161 aaaagcaata catgctgtaa aaactgctgt aagttctata aatgcagaag ctgtactaat
     2221 ttccaaagat ggagtaccag cagcagaatt tgatgaagaa cttgtaaact tggctgaaga
     2281 aactataaaa gatgtattgg gagctgatgc atctataggt atatttaaaa attctggtgg
     2341 agaagatttc cattattata cacaaaaact aaaatgtaaa actacatata ttggattagg
     2401 agctgatgct acaccaggat ttcataatcc aaatgtaaca tttgatacga aagctttaga
     2461 atatggtgta gatatatggt gtagattggt tgaaaagaga ttgggataac atccaaacta
     2521 ataattctac atttaaaatt ataattatag aagttataga aaaagattgc ttatgttaat
     2581 tagaaaataa ttaatatgag caatcttatt ttgatataat gaaactgatt ttggaatatt
     2641 gaaaaaatat gatgggaaag taattatatt ttaaatctat tggacaaaaa agtgatatta
     2701 ttataatatt aagaattgta aaataatacc aaagtgcatc tagtaataga cttaacaatt
     2761 ataaaaattt tattcttagg agggaaaaaa tgagtaagta taattttgac agagtaatag
     2821 atagagtagg aacagattgt gtaaaatggg attttagaac taattgttca acaaaagcac
     2881 aaaaagatgg tttgcctttt tggattgctg atatggattt tgaatgtgca gaaccaataa
     2941 tagaagcatt acgtaaaaaa gttgaacata aaatatttgg atatagttca aatgatagtg
     3001 ataaatactt taatgcagtt tgtgattggt ataaaaggag atttaactgg gaaataaata
     3061 gaaaagatat tatttttagt cctggtgttg tacctgctgt tgctatttta gtaagaatat
     3121 taactaattc taatgaaggt gtaatagtcc aaaaaccagt gtattaccca tttgaagcta
     3181 agataaagag caataatagg gatgttgtaa acaatcctct gatatatgag aatggtactt
     3241 ataggatgga ttatgatgat ttagaagaaa aagctaagtg tagcaacaat aaagtactga
     3301 tactttgtag tcctcacaac cctgttggaa gagtttggag agaagatgaa ttaaaaaagg
     3361 ttgtagaaat atgtaaaaaa tatgacctat ggataatagc tgatgagata cattctgatt
     3421 taattagaaa aggatttaaa catactcctt tacagtcatt atgcccagag tacaaggata
     3481 aaatagttac atgtatagct ccaagtaaaa catttaatct ggcaggaatg cagttgtcta
     3541 atataatagt gaataatgat gaactaaaaa agaaatatca agaagaggtt acagctgttg
     3601 gagttgcaac ttcaccaaat ccctttgcta ttgtagctac aatagcagca tataatgaaa
     3661 gtgaagactg gcttaatgaa ttaaatgatt acttagataa taatatacaa tttattgatg
     3721 aatacttaaa agaaaaccta ccaaaagtaa aacttgttta tccagaagga acatatctag
     3781 catggttaga ttttactgct tatggattaa atgaagtaga acttgaggat ttaatgttta
     3841 aaaaagctaa tgtattattt gatgaaggtt atatatttgg aaaagaagga ataggatttg
     3901 aaagaataaa tgtagcttgt ccacagtctt tattaaaaga atgtatggac agattaaaga
     3961 ctatatttga aaatttataa agtataggta aaaatttata aagtgtttaa aaataaaaaa
     4021 ataataaact tgacaaattt taactaatca cttatcatac tattatgaat aaatagaaaa
     4081 cataagagag ctaaatttta ttgaattaaa ctcttaaaga ctttgaaagg aagagtagtt
     4141 atagaatgta attaaagcga gttggtgatg gtgtgagacc aatatgaagt ctataatgaa
     4201 gaacatcctg gagttgctaa ccgaaatttt aaaagagtag gcttagtcgg aaccaaaccg
     4261 ttatcatatt ggggtgtatc gagtaatatc tgtacattgt gagctgggtt tgaatttatt
     4321 tcaaactaat cagggtggta ccgcggaaaa gcaacctttc gtccctttta tatagggatg
     4381 aagggttttt ttaatggaaa aatatataaa tatagggagt gaatgatatg agcacaataa
     4441 taccaaagga ttataaaagt agtttgaacg taattgatac acaaatagct ataaaaaaat
     4501 taaaagattt ttttgaaatg agactaagta atgaattaaa tcttataaga gtttcttctc
     4561 cgttatttgt attgccagaa acaggtgcaa atgataattt aaatggagaa aaggctgtaa
     4621 gctttgatat accatttatg aataaaaatg cagaaattgt tcaatcactt gcaaaatgga
     4681 aaagattagc ccttaaaaaa tatgggtttg aagttggtag tggtttatat acagatatga
     4741 atgcaataag aaaaaatgaa gaattagaca atatacattc tctttatgta gaccaatggg
     4801 attgggaatt ggttatagat aaaagtagta gaaatgaaaa gactctaaaa gatgttgtaa
     4861 aaagattgta tggagtattt aaagatactg aaatttttgt atgtagtatg tatgaaggta
     4921 taaaagaaat attaccagaa gaaataactt ttataacatc acaagagtta gaagatatgt
     4981 atccagaatt atcaccaaag gaaagagaag ataaaattgt aaaagagaag aaagcagtat
     5041 ttataactca aataggaaaa acattaatat caggagaaaa acatgatgga agaagtcctg
     5101 attatgatga ttgggaattg aatggggata tattatttta caatcctgtt ttagattcag
     5161 cattagaatt atcttcaatg ggaattagag ttgatgaaga atctcttgat agacaattga
     5221 aacttgctgg atgtgaagag agaaaagagt ttgactatca taagatgctt ttaaatggcg
     5281 aacttccgta tacaattggt ggaggaattg gtcagtcaag aatatgtatg tatttcttac
     5341 aaaaagctca tataggagaa gtacaagttg gagtatggcc acaggatatg attcaaaatt
     5401 gtagtagtgc aggaattgaa ttattataat ttaaatataa actaattgat aaaatttata
     5461 tctaatatgt tcatcaaatt aattatatcg gttataatgt agaataacct ataattataa
     5521 gaggtgataa atatggagtt tttaaaaata atcattaata tagttttaga tattttaaaa
     5581 aaaattttgg tcagatttaa aaatgctaaa tttggtttgg tttttgtatt tgatttactt
     5641 aaactacctg attttatgac agataaaaga atcaatatag ttgataaaat aaaggtaatt
     5701 tctgtattaa tttttactat atcctacttt gtatctgggg ttgatataat tccagagatg
     5761 attgcagggg catttggttt tatagatgat gctatagttt taatttggag tataggtata
     5821 gtgaatgaag aaattaataa gtatagagtt atcacaaaaa aagataaaca ttcaaatata
     5881 attgaaaatg tagaattttc tataaaagat gaagaagaat aacaatttat atatgttatt
     5941 ctttttttta ttaacaaaaa atggttaaat tgttgacgga gaggtaaaac tctattatca
     6001 taataagtgg atatccaata tttaactaag tattcaatgt gcaagaatgc ttaatttaaa
     6061 aaagttatgg agggtaaata ttatgaagaa aaaaataggt ttagtgccca aactaatcat
     6121 cggtatcata gtcggtattt taatcggaag ttatgcacca gaaataatag tacaaatatt
     6181 agtaacagtt agtactttat tctcagcatt cctaaaattt gttataccat ttataattat
     6241 aggttttgta acagcaggta tagctgattt agcaacaggt gcaggaaagt tattggggat
     6301 aactacggga atagcatatg gttctacctt aatagcagga ttattatcat ttgcagtatc
     6361 tacattaatc ttcccaaatt ttattgatgc aagtgttgca agtcaaattg gagacccaga
     6421 ggcaggaatg ttagctccaa tattcacaat tccattagag cctatggtag atgtaacagc
     6481 tgcaatcgta tttgcatttg taatgggact tggaatatca gctttaagaa atcatggaaa
     6541 aggagagact ttatttaatt tcttccaaga atttcaagga atcgtaacga aaacgttgtc
     6601 aacagtgatt atacctttat tacctttata catagcagga acttttgcaa atataactat
     6661 agcaggggaa gtatggacaa tattaggggt attctggaaa gtatacttag tagtaatacc
     6721 tttacatttt gtatatatgg catgtcaatt cacagcagca ggtgtatttt caggaaaaaa
     6781 tccagtaaga atgttaaaaa atcaagtacc tggatattta acagctatag gaactcaatc
     6841 ttcagcagca actataccag ttaatgttgg ttgtgcagaa aaaaatggag taagtaagca
     6901 aataagagaa tttgttgtac ctctttgtgc aacaatacat ttatcaggta gtatgatatc
     6961 aataacagga tttacaactg cagttttaat gatgaatggt atgccacatg gaataggtgt
     7021 attattccct tatattgcaa tgttaggtat agcaatggtt gcagcaccag gagcaccagg
     7081 tggggctata atgagtgcac ttcctttcct accaatggtt ggaataccat cagatggtgg
     7141 gcttgcaagt ttaatgatag ctttatactt aactcaagac agttttggta cagcatgtaa
     7201 tgtatcagga gataatgcaa tagcagtagt agtagataaa ataaatgatg gaatgagtaa
     7261 aaaaggaaac aaagaagagc aaagtgctta gttttttaat aatcaaaaat gagttatctc
     7321 aaatagagat agctcatttt ttatggtata aaaaattata aaataaagtg atttttttat
     7381 ttaaaaattg ctttaagaga tgatattaat aatttatttt cattaggttt taatatacat
     7441 actctaaaga aatactcatc tagaccttca aatgaacaac aatctcttat tattattttt
     7501 tgtgggagca gttgctctcg aagagattta gcagtcaatt cctttgtctt gattttacac
     7561 aatatgaaat tacctttagt attgtatata tctaagcttt ttatattctt aagctcttta
     7621 agcaggtaat ctctttcagt gttcattaag gaaatagtat ttgatataaa atctaaatca
     7681 ctaaacatga tttcacccat tttagaagct attatgttta tattccataa atctagattt
     7741 ttatttattt catttttgac attagtgtta gatataagac catatccaag ccttattcca
     7801 ggcgttgaaa aaaattttga tgtacctctt ataacgaata aattagaata atcatcaact
     7861 aattgagtac aagagtatgt atctgtatca gtaaactcta cataagtctc atcaatcatt
     7921 aaaaatgagt ctgtattttt taaaatttct ctcacttcta ctttagtaaa tgcaaatcca
     7981 gttggattac taggattaca gattactacc aaatcataat ctttagcatt gatagttttt
     8041 ataagatttt ctaaatttat atgaaaatta tcttcttctt ttgcaaagta tttttctata
     8101 gaacaattaa ttttagataa ctctttttca tactctgaat aggctggaga gagtaaaaga
     8161 gcttgtttag gattaattgt atgtataaat gatgaaatta gttctgtagc tccactgcca
     8221 agtactatat tatctataga acatttgcag taattggata tagaagtttt taagtctatg
     8281 taatcagggt caggatacat agataccata tctatattgt ttacaatgta ttgtttggct
     8341 aaacttgatg taccaaaagg atttatattt gagctaaaat ccataaattc ttcctttgaa
     8401 aagccatact tactagataa actatataaa ttagctccat ggtttgtgct cataaaagta
     8461 cctccaaaaa taaaattata taatcgataa aaataactga ttaatatatg tacatataga
     8521 ttataataca aaggaatcgt tattccaaat ttttaatgta aaaagcaaaa aagtatggat
     8581 aagctgttaa tttaggttta aaaatgatga aaaagatttt aattgatatt ttggtatgct
     8641 ataatatata agttaataga aggaaagcgg gaggatacaa aatgtacaaa gttacaggaa
     8701 aaatgttgac agaagaacaa ataaaagaaa aagtttatga attaggaaaa aagatagaag
     8761 aagactttaa aggcgaagat ttactagtgg taggtatact taaaggagct agtgtatttg
     8821 tttcagattt aataagatgt atagatttgg atgtaaatat agattttatg agtgttacaa
     8881 gttatggaaa ctcaacagag tcttctggaa cagttaaaat attaaaagat ttagatgtag
     8941 atattgaagg aaagaatgtg ttgattgtag aggatataat agattctggt ttaacattaa
     9001 gtaatctagt tgcagcttta aaaactagaa atccaaaatc tttaaaacta tgtactctac
     9061 ttgacaaacc tcagagaaga aaagctaata tacctgtaga ctatgttgga tttgttatag
     9121 aagacaaatt tattgttggt tatggaatag actatgctga aaagtataga aatttacctt
     9181 atataggtat agttgaggat gtagaataga tttaaatgtg aatcaaaagc actaatttct
     9241 aagggagtta gtgcttttta gttaattata taaaatttta gtaaaggaga catctatatg
     9301 gatattcagt taaatatatt attatttttc caaaatttaa gaaatccaat tttgaacttt
     9361 atatttcttg tctttacaat aagcacagaa gcaccgttat taatattaat tacaacaatt
     9421 atatactggt gtataaataa aaaatgtgga cagaaaatac tgtttgctat aattggaaat
     9481 tttgttgtaa atttaggcat caaagagttt gtaaaagctc ccagaccaat aggaataaaa
     9541 ggtcttgaat cattgagagt ttctactgct ggtggttatt cttttccaag tgctcatact
     9601 caaactgcaa caacattttg ggttagtatt atgactatat ttaaaaagag atatcttcat
     9661 ttaatagctg cagttatggt tttaggagta ggattgtcta ggctgtattt agctgttcat
     9721 tggccaatag atgtgatagc gggttggata ttaggaatat tttttacagt tgtatttgta
     9781 aaaatatttg actatattga tgataataaa aattatattt tacttgtagt tttacttata
     9841 ccatttataa tagtggctat atttctaaat agccctgaat attttgaaaa atttggtata
     9901 atagtaggat ttgtatttgg atatatggtt gaggatagat ttgttaaatt taatacagat
     9961 aataataaca aaaaaataaa ttttagtaat aaaaataagg ggagtaaaaa tataattttt
    10021 tcaagaatat gtaggttttt ggttgggata gtaacaatag gaatgttata tattggcatt
    10081 aagttgttta tttcaatgtt aatagtcact ttaaatatga gtgactctac tatgagtata
    10141 atttttatga attttattaa gaatacagta gttgtttttt atggaatagc aggagctcca
    10201 gcattattta aacttttaaa attaaattga ttttaaggta tagagtcaat agtttaaatt
    10261 aaaaaaatta agggtagaaa agagtgatta tttgaagaag gtagtaataa taggtggtgg
    10321 accagcaggg atgatagccg catcaactgc atgtgagaaa ggctatgatg taacattaat
    10381 tgagaaaaat cataaattag gaaaaaaact tgcaataaca ggaaaaggta gatgtaatat
    10441 tactaacgct tgtgaaatag aggaattaat agaaaatgta cctacaaatg gaaaatttct
    10501 ttatagtgct ttttatactt ttacaaatga tgatgtaata agtatgttta ataatcttgg
    10561 agtaaagact aaaacagaaa gaggaaaaag ggtttttcca gagagtgata aagcatttga
    10621 tattgtaaat gctcttgaaa gacaacttaa aagtaagaaa gtaaatatat tattaaattc
    10681 gaaagtagaa aaaataatat ctaaaaataa taaaattgaa aaagtaattt taaacgataa
    10741 aaaagaaatt aagtgtgatt cagttgtagt agcaactggt ggattaagtt atccacttac
    10801 tggttctact ggtgatggat ataaatttgc aatttcacag gggcacacaa ttatagatac
    10861 aaaaccatct ttaattggta tagaagtaca agaaagtttt acaaaagatt tagaaaaatt
    10921 atcattgaga aatgttgaaa taagggtgtt taatagcaaa caaaagaaag tttatagtga
    10981 ttttggagaa cttgaattta ctagatttgg tttagatgga cctataatca agtctgcaag
    11041 ttgtagaatg aaagatacaa ggaaagaaaa ttacactata ttattagatt taaaacctgc
    11101 attagatgag gaaaaattgg ataaaagagt tcaaaaagat tttcagaagt atacaaataa
    11161 aaaatttgaa aaagcattag atgatttact tccaaaaaaa ctaataccta taataataaa
    11221 cttaagtgaa attaatccaa atacggttgt tcaccaaatt tctagagagc agagaaaaaa
    11281 cttagtccat ttattaaaaa atttaaagtt tacagtaaag agatacagac ctattgaaga
    11341 agctataata acttctggtg gtgtaaaagt aaacgaaata aattcaagta caatggaatc
    11401 aaaattagta gaaggtttat tttttgctgg agaagtaata gatatagatg catatacagg
    11461 tggattcaat ttgcaaatag ctttttctac tggatatttg gcaggtttta attgctaaaa
    11521 attacctgaa ttaaaaatgt ttaaaatcac ataatattat cagcaacaca aaataaatta
    11581 aacagaagga aggtaatcaa catggcaagt aacaataaca acaacagaac agtagtacca
    11641 ggagcaaaag aggctttaaa ccaaatgaaa ttagaaatag ctaatgaact tggtatgagt
    11701 aattatcaac aagttgataa aggaaacctt actgcaagag aaaatggtta tgtaggtgga
    11761 tacatgacta aaaaattagt tgaaatggct gaacaacaaa tggctggaaa aagcaacaga
    11821 tagttataaa taattattta taactattgg ctattagttt agctagagct atctcaaata
    11881 tagaaagtaa tttctaaatt gagatagctt ttttttatta aattattaaa tagatatatt
    11941 tttatgtaat aaattttatg tatttggata aaataataca aatgaatatg ttacataagg
    12001 agtgatgtaa aatgagtagt gtaaattttg aggatttaaa aaacaaattt attaatagtg
    12061 acttagatga aaaaataaga atatatacaa caacagaagg tttatcagta gaacaattta
    12121 aagagctact aaaatattat ccaatacaac atttatctaa actagaaaaa gcacttggat
    12181 agcagtattt aatccaaaat taaaaaggca atttatttaa tattaaaaat attttttatt
    12241 aaataaattg cctttttata ataggtttaa attattatgc ttttgatata taattataga
    12301 ttctctcatt tccaagttca atagacccag tattaataag agtaactatt ccttctatat
    12361 ctctagcagt taagtattta tatggaatta ataaattata accagtatta cttagtaagt
    12421 tttttaattg ggttatttga gagatattga aacattttgc agttttagta gatttttttc
    12481 ttaagttaga taaattttca ttttgaatat ttattaaagt ttctatatag tttctataag
    12541 atatcttaaa gtttgtctca ttgactattt tttcattaag tatactactg ataaaatctt
    12601 gagacaatat attatctgca aatttatctg ctgttaattt tccagatgtt atgccttttt
    12661 gatattttct aagaattttt ttagtatagc agtatatttt atttctcgtt tctaaatcga
    12721 gttgttctat ttgcacaaaa ccacttcctt ctaattataa aaatatttat taaaaatcta
    12781 tacttaacta ataaagcttc aataacttat ttacaataaa tactaaatca taaaatattt
    12841 gttatttttt attattacca agtataaaaa atattataat tgtaaaactt acaaatatat
    12901 gtaaaatatt taggagtgat gaaaatgtta aatgggataa taaagctttt ttattctgaa
    12961 attgtaaaaa caaagattaa taacttagat tcaagtggat attctttaag agatgaatgt
    13021 aaagaaatca gaaatataac tctaaagata gatagtgtat tttttaagct tttaaagtta
    13081 gcttttggtt caatattgct tatggtagct tttaatttaa acatggtttt aggtatagga
    13141 gtgtttttag ttggtgtagt ttatatacta tataaaagaa atatggaaga acaagtaaaa
    13201 gagcatataa ataatgtgaa aaataatatc gacatctcta aaataacttt tatggatgaa
    13261 aaagggagaa caggtctaaa tgcattaatt acattacttc ttataggatt attgacagga
    13321 tttaactgga tattagttgc tagttttgtc gttgtttttg tttttactat aaagaatgta
    13381 tgttaaaata ctaataaata gtttaatata tagggggaga aattgagtat gactaatggc
    13441 agttataaaa tgaagaattt agtggaaata tccgctatgg tgactgaatc tacagatttt
    13501 tttaatataa aagatgacat aatagaaaaa atgttagaag ttgttcaccc tacaaaggca
    13561 tgtgtgaatc tattttataa aaatgattct aaatatgcct acttagtatg ttcgcaaacc
    13621 ttagaatatg tacctcaaat ttttccaata aatagtctta aaggtgcaaa aattgatttt
    13681 gacacatatc cagagtatat acatgaggct gtaaatgaaa aaaagataat atatgtggaa
    13741 aatgtatttg aagattctag agcagaaggt gaacgagatt tagcaaaagc tgaaggttat
    13801 attgggagaa tagtttttcc ttttataata aataacgtag ttgttggatt tatgacttgt
    13861 tttttaaaag aggatgatta tataacagaa caagatatag attttatatc atctgttgca
    13921 tcactcttaa gtttatcaat agaaataact aataaaaata ataatgtaca aattttaatt
    13981 gataaactaa gaggctcaat aagtgccata aatgaagcta ctaaaaaact ataccttaat
    14041 aagagtattg atggattttt ggaaaattta agtaaacaag cgtgtaatat tactaatagt
    14101 aaagaagctt taataattat aaatagtcat cataataagg atgctatagt tagttgttat
    14161 aatgttgagc aaaaaaagaa aacaaattta tatcctatga ttgatatgtt tttaaagaaa
    14221 gagtcattgg gggggtattt aaataattta aaaccatgct caaaaaaggg aataaatttg
    14281 gaaagttata tatattacaa acttcaggat aaaaatgata ctataggatg tatagtttgt
    14341 gcaaatagca aaaactatac tagtgatgat ttaaatattc ttagtatatt gtccaaacaa
    14401 gtttctgttg gtatgcaatt atatgaacat aatgaaaagg aagtaaaaca caaagttctt
    14461 gaaaatgagt tgaacatatt aaataaacaa caacagctta ttatggataa aggtaaaatg
    14521 gattgtaatg atgagaaaga actttatttt taccataaac cagcaagggt agtaggtgga
    14581 gatttttatt atgctacaaa agtggatgac gaacatatag tttatattgt tgctgatgta
    14641 atgggacatg gaatggtatc aaattatgtt gttgcaatga taaaaggtgc ttttaaagta
    14701 ttatgcaatc aatacaatac accaagagaa ataatgacaa atttaaatag gatgttatat
    14761 gatgaatttg acaagatggg agtatttaca acttgtttga taggtattat agatactaaa
    14821 gaaaatatga ttactgtgtc taatgcaggt cactatagtc ctgtagttgt aaagaaagat
    14881 ggcacaatag aaaataattt aaattgtaaa aagggcatac ctattggaat aatggaagat
    14941 gctacttatg aaaataatac tctttcaatg gaagattatg caatggtatg tatgtacact
    15001 gatggaattt tagagataaa aaattcatca aaagaagagt atggtataaa ccgattagaa
    15061 aactttctaa aagaaaattt tagattaaat caacagttaa tagtagaaaa tctaaaattg
    15121 gatttaaaga acttctcatc aaaagataat tatgatgatg atattttaat agttatgtta
    15181 aaggataggt agattgatta tggattcaaa cgataaaaaa ggacttaaaa gtccagagat
    15241 tataataata aatggaagtc caagaattaa taaaaattgc agttttatag caaatgaagt
    15301 aaaagctatg ctagaagagt gtggattaag ttgtaaaata tttaatatct acaatatgga
    15361 tattgaatat tgcacagcat gtggattttg tgaaaaaaca gggtattgca agtttaatga
    15421 tgatatgaag ccattatata aaatgtttga tgattcaaaa ggaactatag taataagtcc
    15481 tgtacatttt gattcaatat cagctaaatt aaagactgtt gttgatagaa ctcaagctat
    15541 atatgcaagt aaatatgtat taaataaacc ttcaattgat agaagtaaga aacggatagg
    15601 aatgtatatt gcagtgggag ggagtaaatc atatgattca cagtttaaag gtggacagat
    15661 tgttatggat tttttcttta agagtataaa tactaaactt ttacacaata tatatttaaa
    15721 caatacagat gatgtatctt atatagataa tcaagaattt aaagatataa tatataaaaa
    15781 tttaaagata tatattgatt caatataatt tgattttgta ggtaatatta tgtataattg
    15841 tattgcaata atttaaataa ttaaaaggag ggaatttcaa tgaaattacc aatagcatta
    15901 tctaataaac atgttcattt gagtcaagct gatatagacg tattatttgg agcaggtcat
    15961 gagttaacta aatttaaacc attatctcaa ccagggcaat atgcctgtga agaaaaagtg
    16021 gatttagtag gaccaaaagg aactttaaaa ggagttagag tactaggacc agctagagct
    16081 catactcaag ttgaaatatc tttagcagat ggtttcccat taggagtaaa agcaccaata
    16141 aaagaatctg gtgatatagc tggaactcca ggtgttaaat tagtaggacc tgctggagaa
    16201 gttgaaatga aagaaggagt tatagttgct tctagacata tacatatgag caatgaagat
    16261 gctgctaaat ttggtgtaac tgataagcaa atagtaaaag ttaaaacatc tggaccaaga
    16321 gcattagtat ttgaaaatgt attagtaaga gctagtgaca gctttaatct agaaatgcat
    16381 gttgatatgg aagaaggaaa tgcagcaggc gttaaaaatg gagatttagt agaattaata
    16441 gttgattaat attataaata gactttatgc tagtagatat tttatttgct agcatatttt
    16501 taaatgtaat aaatttctat aggataaatt taatcgatta gattaattta taaaataaag
    16561 gggtattata aaaaatgtaa taaaaactta caaaaatatg atgtaatatg gtaaaattat
    16621 atatataaaa atttacatat aataaagata attattttac tttttgtact aatataaaca
    16681 aatagataaa aaag
//
LOCUS       DAEOTL010000090        16415 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEOTL010000090 DAEOTL010000000
VERSION     DAEOTL010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16415
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.090"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(75..2141)
                     /gene="fusA"
                     /locus_tag="KRH82_003229"
     CDS             complement(75..2141)
                     /gene="fusA"
                     /locus_tag="KRH82_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBG8656494.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
     gene            complement(2190..2660)
                     /gene="rpsG"
                     /locus_tag="KRH82_003230"
     CDS             complement(2190..2660)
                     /gene="rpsG"
                     /locus_tag="KRH82_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBG8656495.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            complement(2784..3206)
                     /gene="rpsL"
                     /locus_tag="KRH82_003231"
     CDS             complement(2784..3206)
                     /gene="rpsL"
                     /locus_tag="KRH82_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBG8656496.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            complement(3495..6980)
                     /gene="rpoC"
                     /locus_tag="KRH82_003232"
     CDS             complement(3495..6980)
                     /gene="rpoC"
                     /locus_tag="KRH82_003232"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBG8656497.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            complement(7022..10738)
                     /gene="rpoB"
                     /locus_tag="KRH82_003233"
     CDS             complement(7022..10738)
                     /gene="rpoB"
                     /locus_tag="KRH82_003233"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBG8656498.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            complement(11209..11997)
                     /locus_tag="KRH82_003234"
     CDS             complement(11209..11997)
                     /locus_tag="KRH82_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBG8656499.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            complement(12388..12753)
                     /gene="rplL"
                     /locus_tag="KRH82_003235"
     CDS             complement(12388..12753)
                     /gene="rplL"
                     /locus_tag="KRH82_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBG8656500.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            complement(12811..13317)
                     /locus_tag="KRH82_003236"
     CDS             complement(12811..13317)
                     /locus_tag="KRH82_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBG8656501.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     misc_feature    complement(13360..13488)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(13540..14238)
                     /gene="rplA"
                     /locus_tag="KRH82_003237"
     CDS             complement(13540..14238)
                     /gene="rplA"
                     /locus_tag="KRH82_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBG8656502.1"
                     /translation="MAKKGKRYAGALEKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     gene            complement(14309..14734)
                     /gene="rplK"
                     /locus_tag="KRH82_003238"
     CDS             complement(14309..14734)
                     /gene="rplK"
                     /locus_tag="KRH82_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBG8656503.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            complement(14773..15315)
                     /gene="nusG"
                     /locus_tag="KRH82_003239"
     CDS             complement(14773..15315)
                     /gene="nusG"
                     /locus_tag="KRH82_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBG8656504.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            complement(15335..15556)
                     /gene="secE"
                     /locus_tag="KRH82_003240"
     CDS             complement(15335..15556)
                     /gene="secE"
                     /locus_tag="KRH82_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBG8656505.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            complement(15582..15731)
                     /gene="rpmG"
                     /locus_tag="KRH82_003241"
     CDS             complement(15582..15731)
                     /gene="rpmG"
                     /locus_tag="KRH82_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBG8656506.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            complement(15981..>16415)
                     /gene="tuf"
                     /locus_tag="KRH82_003242"
     CDS             complement(15981..>16415)
                     /gene="tuf"
                     /locus_tag="KRH82_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBG8656507.1"
                     /translation="PRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQRNEIERGQVLA
                     KTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVM
                     PGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
BASE COUNT         4578 a         3354 c         2041 g         6442 t
ORIGIN      
        1 atcttgtgct agatgagaga tatctctcat ctagctgatt attttttata tttatattat
       61 taattatttt taaattattt tccttcagct attttcttag caactgaagc tggaacttgc
      121 tcatagtgat cgaatatcat tgtgtaagtt gcacgacctt gagttgaaga tcttaggtct
      181 gttgagtatc caaacatttc tgaaagtgga acgaatgcat ttataacttg tgcaccactt
      241 ctagcttcca taccttggat taatcctctt cttgagttta agtcacccat aacatctccc
      301 atgtaatctt ctggagtaac aacttctact ttgaagtaag gctctaaaag aactgcatta
      361 cctttcttca tagcatcttt gaatgccatt gaaccagcca tcttaaacgc catctcagaa
      421 gagtcaacct catggtaaga accatcatat aactcaacag caacgtctac aactggatat
      481 ccagcaacta taccagattg catagctcct tgtataccca tgtcaactgg accaacatat
      541 tcttttggta ctgatccacc aacagttttg tttgtgaatt tgtatccttc acctggctct
      601 tgaggagcaa ctctaatctt aacgtgaccg tattgtcctc taccacctga ttgcttagag
      661 tacttgtatt caacatcaac tggttgagtt atagtctctc tatatgcaac ttgtggtgca
      721 ccaactttag cttctacttt aaattctctt aataatctat ctactattat ctctaagtgt
      781 aattcaccca taccagatat tatagtttgt cctgtttctt ggtcagtctt aactgtgaaa
      841 gttgggtctt cttcagctaa tttttgaaga gctataccca ttttttcttg agctgcttta
      901 gaacttggtt ctatagcaac agatataact ggctcaggga attccataga ttcaagtatt
      961 attggattag cagggtcaca taatgtgtct ccagtagtag tatcttttaa tcctactgct
     1021 gctgctatat ctccagcata cactttagtt atttcttctc ttgtattagc atgcatttgt
     1081 aatatacgac caattctttc tctcttattc ttagttgcat ttaaaacata agaacctgat
     1141 tctaatgttc cagaataaac tctgaagaac gctagttttc caacgaatgg gtcagtcatt
     1201 attttgaatg ctaatgcaga gaatggctct tcatcagaag aatgtctttc agcttcttct
     1261 ccatctgcta atataccttt tatagctggt atatcagttg gcgctggtaa gtaatctaaa
     1321 actgcatcta ttactaactg aacacctttg tttctataag ctgtaccaca gaaaactggg
     1381 ttcatttcac aagctatagt agcttttctt atagcaactt ttaattcatc tatagtaagt
     1441 tcttcacctt caaggtattt catcattaat tcttcatcag tttcagctac tgattcaact
     1501 aatttttctc tccactcagc agctaattct ttcatatctt ctggtatatc tgtttcttcc
     1561 atttcaaccc ctaggtcgtc tttgtatata acagcatcca tttttaataa gtctattata
     1621 cctataaatg aatcttcttt acctattggt aattgcatag gaactgcatt agaatttaat
     1681 ctagatttca tcatgcttac aacattgtag aaatctgcac ctaatatatc cattttattt
     1741 acaaaagcta ttctaggtac tccataagtt tcagcttgtc tccatacatt ttctgattga
     1801 ggctcaaccc caccttttgc acagaataca gcaactgaac cgtcaagaac tcttagagat
     1861 ctttcaacct caactgtgaa gtccacgtgt ccaggagtat ctattatgtt tattctatgg
     1921 tctttccatg aagcagtagt agcggcagaa gttattgtta tacctctttc cttttcttgc
     1981 tccatccagt ccatttgaga agctccttca tgagtttctc ctattttatg agtttgccca
     2041 gtataaaaca ggattctttc tgtagtagta gtttttcctg catctatatg agccatgatt
     2101 cctatattcc tagttctttc caaaggaaac tttctagcca tggttatcct ccttatgata
     2161 tcctcaattt tataagatat ctatatatcc taccatctgt aatgagcaaa tgctttatta
     2221 gcttctgcca ttttatgagt atcttctttt ttcttaactg aagctccagt gttgttagct
     2281 gcgtccatta tctctttagc tagcttttca accattcctt tttctccacg agctctagta
     2341 tattttacta gccatcttaa acctaatgtt tgtcttcttt caggtctaac ttcgattggc
     2401 acttggtagt ttgccccacc aactcttctt gcttttactt ctaaaacagg cattatatta
     2461 tccattgctt tattaaatac ttctaaagct tcttctcctg tcttttcagc aacaattgcg
     2521 aaagcatcat aaactattct ttgagacttt cctttttttc cgtctaccat tagattattt
     2581 attaatttag taactacctt actcccatac ataggatctg gtaaaacttc tctttttgga
     2641 atattacctt ttcttggcat ttcgcttccc tccttaatta tttaacttaa atcataggta
     2701 ctcgacataa atcatttaat gccgtgatgc cgtaaatata tatatattta aagcaccgaa
     2761 ctataatcaa tcattaattg tttttacttt ttagcttctt taggtctctt cgcaccgtat
     2821 ttagatcttg attgtcttct cttatcaaca cctgctgtat ctagagtacc tcttagtata
     2881 tggtatctaa cccctggaag gtcttttact cttcctcctc ttataagaac aacactatgc
     2941 tcttgtaagt tgtgtccttc tcctggtata taagcagaaa cttctatacc attagttaat
     3001 ctaactctgg caacttttct taaagctgag ttaggcttct taggagtaac tgtttttact
     3061 gaagtacaaa cccctctttt ttgtggggca ctagcgtcag ttactttctt atttaaagag
     3121 ttgtaacctt tttgtaatgc tggagcagta gatttcttct ctagcgcttt tctactttta
     3181 cgaactaatt ggttaattgt tggcatcatc tgcacctcct tccaaatttt cgatcttatc
     3241 agtgaccgcc aactacatca atatgaatat tcatactgac tgattgtaac attcgttact
     3301 tacaatttaa tgtctataac acataaatat gtgatattag cacttttcta gcttgatgct
     3361 ttttagttct catttattgc catctaaaag tcactaagaa cttgttcaag cccttagtgt
     3421 acttttaaac aacacacttt actattttaa caccacaaat aatggttgtc aagatttctt
     3481 tactctatat gctattaatc ttcaattttt tcaacagcta tatttctata tttcttcatt
     3541 cctgttcctg ctggtattaa cttacctaat ataacatttt ctttaagtcc tattaagtgg
     3601 tcttctttac cttttattgc tgcctctgtt aatactcttg ttgtttcttg gaaagaagct
     3661 gctgataaga atgaatcagt tgcaagagat gctttagtta taccaagtaa aactctttta
     3721 gcaactgctg gtcttagacc tttatctata gcatctttat tacattcatt gaatgttaat
     3781 acatcttcat atccacctgg caataaatct gtatctcctg ggtcttcaac ttttacttta
     3841 gatagcattt gtcttactat aacttctata tgcttatcat taacatcaac cccttgaagt
     3901 ctatacactc tttgaacttc tttaactata tattcttgaa ctcccttaac accatttact
     3961 cttactatat catgaggatt tataaatcct tgtgttagag ggtctccagc ctctagcatt
     4021 tgaccttgct taacttttaa tctagaacca tatggaatta catatgtttg agtctcgcct
     4081 tcttctggta ttacatttac ttcttttctc tttcctgttt catcaatttc aactctacca
     4141 gatacttcag ttattacagc taatcctttt ggttttctag cttcaaataa ttcttcaacc
     4201 cttggtagac cttgagttat atcagctcct gcaactcctc cagtatggaa tgtacgcatt
     4261 gtaagctgag tacccggctc accgatagat tgagctgcta ttataccaac tgcttcacct
     4321 atattaactt cttttcctgt tgccaagttt ctaccataac acttagaaca aactccatga
     4381 ttagttttac agttaagaac tgttcttatc ctaatttttt caattcctaa agctactata
     4441 gtttctgctt catcttcttg tatcattgaa tcagcctcaa ctataacttc tccagtttca
     4501 ggatttaata tagggtctat agtatatctt cctacaattc tatcatatat ctcttctata
     4561 acttcatttc cttcttttat agcataaatc tctgtagtat cttctgttcc acaatctatt
     4621 tcccttacaa taacatcttg acttacatca acaagtcttc ttgttaaata tccagattca
     4681 gctgtacgta tagctgtatc ggcaagacct tttctggcac catgtgaaga tgtaaagtat
     4741 tctagtactg ataaaccttc acggaaatta gatttaactg gtatctcaac tgttttacca
     4801 gatgcatttg ccataagacc acgcatacct gccagctgtc taatttggtt tttagaacct
     4861 ctggctcctg aatgtgccat tatatatata ttatttaatc tatctagtcc acccataaga
     4921 gcatcagtaa ctttatcagt tgtttctgtc catgtctcta taactttttc atatctttct
     4981 tcatcagaga ttagacctct tctgtatgct ttttcatact tatcaacttt agcttctgcc
     5041 tcagctataa atactttctt ttcttctggg acactcatat catcaacagc aactgttatg
     5101 ccacctaatg tagaatattt aaatcctaga gcttttatat aatctagtaa ttcagctgtt
     5161 tctgtatttc cgtgttttct aaagcattta tctattattt taccaagaga ttttttatct
     5221 gctaagaaat caacttcaag tgcaaatgga ttttcttttc tatctacaaa acctaagtct
     5281 tgaggtatat tttcattaaa tataaatcta ccaacagtac tttcaaccaa tgaacttctt
     5341 ccatcttcaa gtgttacctt aagtttcact aatgcatgta gatgaactga tttattgtaa
     5401 taagcaagta atagttcatt aaagtcttta aataccatac ctgttccttt agctccatct
     5461 tgggcttcta ttgttagata atagcaacct aaaaccatat cctgagatgg agtagttata
     5521 ggtgaaccat ctttaggagc aagtatatta tttacagaaa gcattaagaa tcttgcttct
     5581 gcttgtgctt ctactgataa aggtacatga actgccattt ggtcaccatc aaagtctgca
     5641 ttataagctg tacatacaag aggatgtagt tttatagcct taccttcaac taagattggt
     5701 tcaaatgctt gtatacctaa tctatgtaga gtcggtgcac ggttaagaag aactggatga
     5761 ctttttataa catcttctaa aacatcccaa acttctggct taactttttc tactatagat
     5821 ttcgcacttt ttatattatg tgcataacct tctttaacta atttatccat aacaaatggc
     5881 ttgaataatt ctaatgccat cttctttgga agtccacatt gataaaattt aagttctggt
     5941 ccaacaacta taacagaacg tcctgagtag tcaacacgct taccaagtaa gttttgacgg
     6001 aaacgacctt gcttaccttt taacatatct gataaagatt taagtggtct atttccaggt
     6061 cctgttacag gtctacctct tctaccatta tctatcaatg catcaacagc ttcttgaagc
     6121 attctttttt catttcttac aattatatct ggagctccaa gctctaataa tcttttaagt
     6181 ctattgtttc tatttataac tcttctatat aaatcattta ggtctgaagt cgcaaatctt
     6241 ccaccatcaa gttgtaccat tggtcttaaa tctggtggta ttactggtat tgcatctaaa
     6301 atcatccatt ctggtttatt tccagacttt ttaaatgcct ctacaacttc taatcttctt
     6361 attgttctaa ctttcttctg ccctgtacta tcttttaact ctgctcttag gtctttactt
     6421 tgttgctcta aatctatatt ttgtagtaat gtctttacag cttcagcacc cattcctaca
     6481 gtaaaagtat atccatactt ttcaagagca gttctgtatt ctttttctgt aagcaattgt
     6541 ttttcgttta atccagtctc tcctggatca actaccacat atgaggcaaa gtataatatt
     6601 ttttctaacg atcttggtga catatcaagt aaaagtccca ttctacttgg tatacctttg
     6661 aagtaccaga tgtgagacat aggagcagct agctctatat gtcccattct ctctcttctt
     6721 acttttgatt tagttacttc tactccacat ctatcacaaa ctacaccttt atatctaact
     6781 cttctatatt taccacagtg gcactcccag tctttttgtg gtccaaatat tctttcacag
     6841 aaaagaccat ctttttctgg ttttaaagta cggtaattta tagtttctgg ctttttaact
     6901 tctcccctag accattgtct tattttttct ggagaagcca atgctatttt tatcgactcg
     6961 aaattgttta attcaaacaa ggagttctct cccttctatt tgagatttac attaattaaa
     7021 tttacatatc aaagtcatca ctatcaaaat ctatttcttc ttcaaataaa tcatcttcag
     7081 tgaattcttc taaattctct atatcctcat cttctgcatt ttctgcaaaa tcatcttcaa
     7141 tttcttctat tatattactt tcttcaactt ctcccatatg atttacaaca tctagctcaa
     7201 attcacctat tgtatcatct tcatccacag attctcttac ttctatttct tggtcttcat
     7261 ctgtcaatac ttttacatct aagcataaac tttgaagttc ttttataaga accttaaatg
     7321 attctgggat tcctggttca ggtatatttt cacctttaac tatagcttca tatgttctaa
     7381 cacgacctac aacgtcatca gacttaacag taagtatttc ttgaagtatg tgagcagctc
     7441 catatgcttc cagagcccaa acctccatct ctccaaatct ttgtccacca aattgtgctt
     7501 taccacctag tggctgttga gtaactaatg agtatggtcc agtacttctt gcatgtagtt
     7561 tttcatctac taagtgatgt agtttcaagt agtacatata tccaacagtt attctgttgt
     7621 caaaagactc acctgttcta ccatcatata aagttaattt accatctcta ggatacccag
     7681 cttcttcaag agcatccatt atgtcatact cattagcacc atcgaatact gatgttgcta
     7741 cataccatcc taatgtctta gcagcaagtc ctaaatgaac ttctaaaacc tgaccaatgt
     7801 tcatacgtga tggtatacct tgtgggttaa gtattatgtc tagtggtgtt ccattttcca
     7861 tgaatggcat atcttcttca ggtaatactc ttgatataac ccctttatta ccatgacgac
     7921 cagccatttt atctccaact tttatttttc tctttttagc tatatagcat cttactaatt
     7981 catttactcc tggagataaa tcatctccat tttctctagt aaatactttt acatcaacta
     8041 ttataccaga ttcaccatga ggcactttaa gtgaagtatc tctaacttct ctagcctttt
     8101 ctccaaatat tgcacgaagt aatctttctt cagcagtaag ttcagtttct ccttttggag
     8161 ttactttacc aactaatata tcacctgagt ctacttctgc acctattctt attatacctc
     8221 tgtcatctaa gttcttaatt gcactatctc caacattagg tatatctcta gttatttcct
     8281 ctggccctag ttttgtatct ctagcttcac attcatattc ttctatatga attgttgata
     8341 atctatcttc tttaactaat ctttcattta ttaatatagc atcctcgtag ttataacctt
     8401 cccaagtcat gaatgctata agacagtttc ttccaagtgc aacttctcct aaatcagttg
     8461 ctggaccatc tgctataaca tcacctttta ttatctggtc acccttattt attataggtg
     8521 tttgatttat acaagtacct gagtttgaac gtttaaactt aagtagatta tatctatctc
     8581 tgtttccatc ttctcttttt ataattattt catctgctgt tactctttct gctataccag
     8641 aatttctagc aacaacaact gctccagagt cttttgctgc tctgtattct ataccagttc
     8701 ctataattgg tgcttctctt ctaactagag gcactgcctg acgctgcatg ttcgctccca
     8761 taagggcacg gttggcatca tcattttcta agaaaggtat catagcagtg gcaacagata
     8821 caacctgctt aggagatata tccatgtaat ctactctact ttcaggaacc atttcaacag
     8881 caccatttac agttctacaa acaactctat ggtttacgaa tttaccatct tctgttaatg
     8941 gctcatttgc ctgagctctt acgaataaat cttcttcgtc agcagttaaa taatgtattt
     9001 catcagtaac tgttgatgtt tctttatcaa attttctata tggtgattct ataaatccaa
     9061 attcatttat ttttgcataa gttcctagag agtttataag accgatattt ggtccctctg
     9121 gagtctctat tggacacatt ctaccatagt gtgaatggtg aacgtcacgc acttcgaatc
     9181 cagctctttc tcttgaaaga cctccaggcc caagggctga taatcttctc ttatgcgtta
     9241 actcagatag aggatttgtt tgatccatga actgagataa ctgagaacta ccaaaaaatt
     9301 cttttattgc agctgaaact ggtcttatgt taactaacgc ttgaggcgtt atagcttcca
     9361 tatcttgaac cgtcattctt tcttttataa ctctttccat tcttgaaaga ccaattctaa
     9421 cttgattttg taacaattca cctacagatc ttattcttct gtttcctagg tgatctatat
     9481 catcaatatt tcctatatta tagaatatat tgaactcata acttattgaa gctattatat
     9541 catctaataa tatatgtttt ggtataagtt ctttaattct tgattttata gcctctttta
     9601 tttcttcttc atcactatat ccatctaaaa tttcttttaa agttggataa tgtacttttt
     9661 cttttatgtt taaatcatct atgtcaaaat caatgtgaga cttaatatcc acaaaattat
     9721 ttcctataac tctaactttt ttatcatcat ccattagtag atttactaca tttatacctg
     9781 cattttgtat ggctttagcc aaatcatagc ttattttttc tccagctttt acaaatactt
     9841 ctccagtttc tggatttatt atgtcttctg ctgaaatttt attcattatt ctataacata
     9901 aagcaagttt cttattgaat ttatatctac caacttttgc taggtcatat ctttttgggt
     9961 caaagaataa agcatttaat aaagatgatg cactttctac agtaggaggt tcacctggtc
    10021 ttaatttttt gtatatctct acaagacctt cttctactgt cttagtatta tctttttcta
    10081 atgtagcaga taatctctca tcttctccta aaaggtcaat tatctctgca tctgttccta
    10141 ttcctaaagc tctaagtaaa actgtaactg gttgttttct tgttctatca actcttacag
    10201 atattacatc attagaatct gtttcatatt ctaaccatgc tcctctatta ggaattacag
    10261 tagatgaaat caatctctta cctgttttat ctctttcttc cgcatagtaa acaccaggag
    10321 atctaactaa ttgacttact ataactcttt ctgctccatt tataacgaaa gttcctcttt
    10381 ctgtcattaa agggaagtca cccataaaca cttcttgttc ttttatctca cctgtttctt
    10441 tatttataag tcttacctta acctttagag gtgcacaata tgtagcatct ctctctttac
    10501 actcttctat atcgtacttt ggtttatcat ctagagaata gtcgacaaat tccaatataa
    10561 gattaccagt ataatcttct attggtgaaa tatcatcaaa cacttctttt aaaccttctt
    10621 ttaaaaacca ctcataggaa tctacttgaa tttctataag atttggcaca tcagctattt
    10681 ccttaatttt agaaaagctc attctagttc ttttacctat cgtgacagga tgtggcattc
    10741 acttttcacc tctcaataat taaaaataaa acaatagttc attctaacgc atctaataat
    10801 tttagcataa tgtcaagtat ttttcaatat attttttatc ttatatgtaa actatgcatt
    10861 atttttgatt ttttgtaaat tattttaagc atatattatg tattatgtac aattttccaa
    10921 tataaaatcc atatttttca tttataggtc taattttcta taaaaaattt tatacaagta
    10981 ccatcccccc tatttaatta taattccata ttaaaatgat tgtaaataat tacatttata
    11041 caaatatata caatttatta aaatatacaa aataaagacc ataaataaat ttaacttgga
    11101 attttgaacc tcaaaccttt ccaatataaa ttatatctat ggcctttata aaaatatcat
    11161 ttctactata actaatgcat aagctttcat tgcatattag taatttaatt atcctaatat
    11221 attatctgca aattgtggag taggtaaacc aaatcctcct gcaacttcaa gtaaatcccc
    11281 tgttataaat gatgagtcat cactagcata gaatagaaca gcttttgcta tatcatctgg
    11341 ttcccctata cgatttaaag gaacatgctt taaaaattct tttatgaact ctggagacat
    11401 attgtctaat gctgctttag ttgcaataag ccctggaagt acagcattac atctaacatt
    11461 gtctttagca tattgtgtag ctatgttttg agttaatgag ttgattgctg cttttgatac
    11521 acagtaagct attctagata aatcaggtaa tactgaacct atacttgata tatttactat
    11581 acttcctttt ccattcttta tcatatgagg aattgctgct ttacatggta aatacacact
    11641 ttttaaatta gtatttactg tgtcaaagaa attatctgta tctccagtta caaggtcttt
    11701 gtcaagagaa gggtttgttg aaccaaaatt gtttacaagt atatctatct taccttcttt
    11761 tttaactacc tcttctatca ttgaggtaaa ggtctcttct tcacgagcat taaagtaaac
    11821 aaacttagca caaccacctt ctgcacttat tttatttata acttcattag ctaattcttc
    11881 tgaacgagct gctaagtaca cagttgctcc attttttgct aatatctctg ctgatgctaa
    11941 tccaatacct tttgttgctg cagtaactac tgcaattttt ccttgtaatt tttccattat
    12001 taactcctcc ttgaatatgt cctttaaatc ctacaaattt cgatttttct aaatatctaa
    12061 cttattttaa aatttatatt tgttaattaa ttatttatta cattttattt ataaaacact
    12121 cgtgtatttt tttaaactaa aatgtaaaat tttacatttt agtttaatta tatactttat
    12181 atacagacat tacaacaatt gtttatattt taatttgata ataatgttaa attaaaatac
    12241 cattacacca tatatgatac ccttaattta gtactattat ataaattttt ttattttata
    12301 aaaatacttt ctttataatt ccaaatactt tctttatagt tttttataaa taaaaaaaga
    12361 tacccaatgg gtatcttttt aaagaaacta cttaacttct actttagctc cagcagcttc
    12421 taatttctct tttatttgat cagcttcttc tttagaagct ccttctttaa ctgtcttagg
    12481 agcattgtca actacttctt tagcttcttt taatcctaat cctgttattt ctctaactgc
    12541 ttttataact ccaacttttg aagaaccaac gtcagttaat actacatcaa actcagtttt
    12601 ttcttcagca gctggtccac cagcagctgc accagctacc attactggag ctgaagctga
    12661 tacaccgaat ttttcttcag cagctttaac taattcattt aattctaaaa ctttcatatt
    12721 ttctatagct tctaatattt gttctattgt catttttagc acctccgaat tttatttcaa
    12781 attaatattt ataatttttt agttaagcaa ttaagcttct tcttgacctt ctgccttttt
    12841 cgctattgca tctattaagt atgcgaagtt tgatactgga gcttttaagc taccaagtaa
    12901 tttagcgata agaacttctc ttgatggtat gttagccatt tcaacaatct tagattcatc
    12961 atagaatgca ccttccacaa tacccatctt taatttcatt tttggatgag aatccatgaa
    13021 tccttttaat attctagctg gagcaactgg atcatcatat ccaaatgcta tggcattagt
    13081 tccaactaat aattcatcat taaattgctc tataccaact tctttagctg ctcttctaac
    13141 taaagtattt ttgtatactt tgtaatctac accagcttct ctcatttgtt ttcttaactc
    13201 agttacttct tcaactgtta atcctttgta atctacaaca acagcagcag aagatttttg
    13261 taacttttca actatctcag aaacaacttc tgatttaatt tctatagctt ttctcatata
    13321 gatgtgcacc tccttcacca aataggctta gtatttaccg caacattata aaaagctttt
    13381 gttgccaaaa gtagacatca aaagctttag taatctcaat ttatctaaaa cctcggcggg
    13441 atattaagct ttcgcaccca ctatctacgg caaatctatt cttttttaca ttgacaagtg
    13501 atataataac atttttgtca acctgtgtca acagttttat tattcagctg ttcttgctgg
    13561 gtttatttta actccaggtc ccattgaaga agctactgtt atacttctta aatattgtcc
    13621 tttagcagca gctggtttag cttttattat agcatccatt aatgcagtaa agttttcagt
    13681 taatttttct ccaccaaatg atacttttcc tactggaacg tgtattatgt tagttttgtc
    13741 taatctgtat tcaactttac cagcttttat ttcatctata gctttagcta catcaaatgt
    13801 aactgttcct gatttagggt ttggcattaa acctttaggt cctaatactc tacctaatct
    13861 acctactaca cccatcatat ctggagtagc aactactata tcaaagtcaa accagttttc
    13921 accttgtatt ttttgaacta attcttcagc tcctacaaag tcagcaccag cttgttcagc
    13981 ttctttagct ttttcacctt tagcaaaaac taaaactctt tttgttttac cagttccatg
    14041 aggtaataca actgcacctc ttacttgttg gtcagcatgt cttgagtcaa cacctaattt
    14101 aatgtgtgct tctactgtct catcaaattt agctccagct atatctgaaa ctaatgttaa
    14161 tgcttctgat gcatcataaa atttagttct atctactttt tctaatgcac ctgcatatct
    14221 tttacctttt ttagccattt tattttcctc ctcgtggtta atttcggctt ctagcctccc
    14281 actttataaa aaaaagtgta tcttttaatt agtcttcgat tacaacaccc atgcttctag
    14341 cagtaccagc tatcatactc atagcagctt ctactgatgc agcatttaag tcaggcatct
    14401 ttaattcagc tatttctctt acttgagctg aagtcatttt agcaactttt ttcttgtttg
    14461 gttctccaga acctgatttt aagtttaatg cttttttaat taaaactgca gctggtggag
    14521 tttttgttat aaaactgaat gatctatctt gatatacagt tataacaact ggtattatca
    14581 ttccagcttg atctgcagtt ttagcattaa attcttttgt gaatcccatt atattaacac
    14641 catgttgtcc taatgctggt ccaactggtg gcgctggagt agcctttcct gcaggtattt
    14701 gtaattttat ttgacctata acttttttag ccattttgag cgcacctcct cagatttttc
    14761 tataatatag tattagattt tttctatacc ttcaagctct attacaaata gagtcctttt
    14821 accaaatgca tttatgcata ctttgacttc tctattttct aagtcaattt cttctatgtt
    14881 acctatttgt ccactaaatg gtccttgaga tacttttact gtatctccta tttcaaaatc
    14941 aatatcgcta tttactactt taggatctgt tgtgtctatc cccatagctt tgacttcgtc
    15001 ttcacttaat ggcactggtt ttgaaccagg tccaacgaaa cctgtaactc ccttagtatt
    15061 tcttactaca taccaagatt catcagttat tatcatttta accaaaacat aacttggata
    15121 aactttacgt tgtctagttt tttcttttcc agttttagta gtttccacta cttcttctgt
    15181 tggaacaact acttgtctta tgcagtcttc catacctctt gttttaactg ctttctcaat
    15241 tgtagcttta actttatttt catgtcccga ataggtatga actacatacc aacttgcttc
    15301 ttgtaattct gacatttaac ttacctcttt tcgtctattt tagtaataac gctagtgcac
    15361 cagataatat agtgtctata ccccatacta atatagtgca tgaaataact acagttaaaa
    15421 ctatacttgt gtttttaaac agttcctttt ttgtcggcca tgtaactctt tttaattctt
    15481 gtttagtttc ttttaagtat ccaaacaaac taaacctttt tttagttttt gcaccgtcat
    15541 ttttttgggc agccattcca tactcacatc cttataaaaa actattttgt ttctttatga
    15601 gttgtatgct ttttacagaa tctacaatat ttttgtaatt ctattctgtc tggattgttt
    15661 ttcttattct tagtagtgtt gtagtttctt tgcttacact ctgtacatgc taaagttact
    15721 ttaactctca tctgatacac ctccaacttt gtaatacaat aatatatatt gttaatatat
    15781 gtgaatataa tatctttaaa atatgtattt attaaaaatc tacagtattc aagatattat
    15841 taacttccta taatcattac cttgtataag ttatcacaaa atcctatgct gtgtcaatgt
    15901 ttttgtattt ctatgttaaa aaaagaggag cataacccct ctttttgtta ttccttttaa
    15961 tccatcagtt tagtaaagaa ttactctatt attgtagcaa caactcctga agctactgtt
    16021 cttccacctt ctcttattga gaatcttaat ccctcttcta caactattga gtttattaag
    16081 tctacttcca ttgttacgtt atctccaggc attaccatct ctattccttc tggtaactta
    16141 caagctcctg ttacgtctgt tgttctgaaa tagaattgtg gtctatatcc atcaaagaat
    16201 ggtgtatgtc ttccaccctc ttctttttta agtacatata cttctgctgt aaactttgtg
    16261 tgtgccttta ctgatccagt ctttgctagt acttgtcctc tttctatctc gtttctttgt
    16321 actcctctta ataatgctcc tatattatcc cctgcttgtg cttggtctaa taattttctg
    16381 aacatctcta ctcctgttac tactactttt cttgg
//
LOCUS       DAEOTL010000091        16040 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEOTL010000091 DAEOTL010000000
VERSION     DAEOTL010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.092"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            34..576
                     /locus_tag="KRH82_003243"
     CDS             34..576
                     /locus_tag="KRH82_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBG8656508.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            904..2397
                     /locus_tag="KRH82_003244"
     CDS             904..2397
                     /locus_tag="KRH82_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBG8656509.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2471..2704
                     /locus_tag="KRH82_003245"
     CDS             2471..2704
                     /locus_tag="KRH82_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656510.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPSTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2860..3624
                     /locus_tag="KRH82_003246"
     CDS             2860..3624
                     /locus_tag="KRH82_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8656511.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(3909..7088)
                     /locus_tag="KRH82_003247"
     CDS             complement(3909..7088)
                     /locus_tag="KRH82_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBG8656512.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPTNLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMKLENFDVILTTYGTLRNDLDKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7369..9546
                     /locus_tag="KRH82_003248"
     CDS             7369..9546
                     /locus_tag="KRH82_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8656513.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKNLIDREYIE
                     KYVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9560..9982
                     /locus_tag="KRH82_003249"
     CDS             9560..9982
                     /locus_tag="KRH82_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656514.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10390..11193
                     /locus_tag="KRH82_003250"
     CDS             10390..11193
                     /locus_tag="KRH82_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBG8656515.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADAVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11186..11854
                     /locus_tag="KRH82_003251"
     CDS             11186..11854
                     /locus_tag="KRH82_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBG8656516.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12090..12752
                     /locus_tag="KRH82_003252"
     CDS             12090..12752
                     /locus_tag="KRH82_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBG8656517.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAMGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12812..13609
                     /locus_tag="KRH82_003253"
     CDS             12812..13609
                     /locus_tag="KRH82_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8656518.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13727..14917
                     /locus_tag="KRH82_003254"
     CDS             13727..14917
                     /locus_tag="KRH82_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656519.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15026..15775
                     /locus_tag="KRH82_003255"
     CDS             15026..15775
                     /locus_tag="KRH82_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBG8656520.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
BASE COUNT         6232 a         1680 c         2662 g         5466 t
ORIGIN      
        1 aaaaattggc ttaaaagaag gtgaaaaaag taaatgaaaa tatgcataac agtaggtcat
       61 agtatactaa aaggtggtaa aagtacaggt gtaaatggta tagttgatga atacaattat
      121 aataaaaaat tagctcctat gttagctgag atgcttataa gtcaaggtaa tacagtagat
      181 gtaataattt gtccagaaag gcactttatg tcagaaagag aagaattttt ctatagagtt
      241 ccaaaagtaa acagtggtaa atacgattta ttagtagagc tacatttaaa taaagctgat
      301 ggaacacaat gtggtacaga agtgctttac tatggcactg aaggattaga atatgctaaa
      361 agagtatcta atagacttgg agaattattt gaaaatagag gagctaaaaa aagagaaaat
      421 ttatatatat tgagaaatac aaatccagtt gcaatacaga ttgaaagttt tttctgtgat
      481 aatgtgaatg attgtaacaa agcaaatgaa tcaggttatg attatatagc acgattgatt
      541 acagaaggta tattgaataa agatataaat atgtgagatt atggtgattt aggtattgat
      601 taataccttt taatattaga tataaataaa aatacaatgt attagtataa tttaaacttt
      661 caaaagatag attagtttga ttattgacaa gagatacctc cttgaaaata ttgatttatc
      721 agtatattta aggaggtatt taaatataaa aatttaatta atttgctact aaactatagg
      781 tttatagagt atatattttt atcttcagtc taataaataa tataaaaata gtagaacctt
      841 gtattataat aatataatgt agaaaaatat atagataaga taaatataat aaggtggtaa
      901 tatatgaaat atacatttga aaaatttaag ttaaatgaaa agatacttaa gtcattgaag
      961 agtttaggat ataatatacc ttctagagta caaagagaag ttattccaaa attattaaaa
     1021 ggtcaaaact tagtagttag gtcaaaaaca ggaagtggaa agacagcaag ttttgcaata
     1081 cctttatgcg agaatataaa tgtagattac aataatattc aagctcttat agtggttcca
     1141 acaagagaat tagccttgca agtaaaagat gagatatcag atatagggag actaaagaag
     1201 gtgagatgta gtgctatatt tggcaaacaa tctataaaag accaaatagc tgaattgaaa
     1261 caaagggttc atattgttgt agctactcca ggcagaatac ttgatcatat aaatagaggt
     1321 tctattaagt tggaaaatgt aaagtattta gtaatagatg aggcagataa aatgtttaat
     1381 aaaggttttg ttgaacaaat ggaaaaaata ttattaaatt tacctaagga gaaaatagta
     1441 agtctttttt cagctacaat agatgaagag ataaaatata tatgtgaaaa atatatgcta
     1501 gattacagtg ttataaatat agaagaaaat gagagcgata ctaatcaaaa aacaagacaa
     1561 atagatgaca aaataatcaa ggcaaatgga agagagaagt acatcctttt aaaagaatta
     1621 atatacagcg aaaatccaaa gagtgtgata atattttgta ataccaaaga gaaagtatct
     1681 aaattatata acaagatgag taaagagggt tttttaataa gagagttaca tgcagattta
     1741 tcacaagaaa gaagaatttt tgtaattaag gattttaaaa accaaaaatt taatatatta
     1801 gttagtagtg atgtagcgtc cagaggaata catattgatg atatttcttt agtaataaat
     1861 tatgatgtgc cacaagataa agaaaactat atacatagaa taggtagaac tgggagaaaa
     1921 ggaaatagtg gaaaggcaat tactatagta actgaaaagg atgaaaaata tatagagaat
     1981 atagaaacgt atataggata taaaataaat gaattaaaag atatagaaaa aagtagaatt
     2041 acacatggca aagttttgtt tgaagaatat tcaaaaggaa tcctaaaaaa agtatcaaag
     2101 agaaaaaaag ttgataaaaa ttcttacaaa agtaaagata taaaactaaa tatagaaagt
     2161 gaagttgtta aattatattt aaatgctggt aagaagaaga aaataagagt tttagatata
     2221 gttggtgcat ttagtaatat aaaaggtata actaatgatg atataggtgt aattgaagtt
     2281 caagatttat gttcatatgt agatatatta aattataagg gagatttgat attaaaaaaa
     2341 tataaggaga tacctataaa gaaaaaaatg gttaaagtga aaagagatat acgataattt
     2401 agtcaatatt gatgaattgc tttgttatcg aaatgaagtt gcaaaaaaca caatagaagt
     2461 tgttaaggat ttgaaagctg aagatatgaa acgaaaggtc tctccaattg acttagaaag
     2521 gattttggtg actggaggag taataaagca tgaagattct atttggttgt tggacttttg
     2581 ggggaataaa gatattgctg gaattttgct tatgccttct actcgtcatg ttatacttca
     2641 tttgaatgat tgttgtaaat ggaaggaata ttttcgtaca aaaaagaaat tttacagaag
     2701 ttaaattata ataaattaga caaacaatag ataaattagc aaggaatgtt gattttatct
     2761 acattctaag ttatactatt tttaagtggc taatggaata gtcattttaa atataagtaa
     2821 taaatatata cctataggga tattaaaggg gggaaatata tggcatattt taactataac
     2881 gacaaacagt gctactataa tgaaattggg gatggtacac cattactttt tttacatgga
     2941 aatacagcct cttccaagat gtttaatgat ataatcgatt tttataaaga tgaatataaa
     3001 gtaatattaa ttgattttgt aggtcatgga aaatctcaaa tggtcgataa attttctgct
     3061 gacttatggt ttgatgaggc tatgcaagtg atatgttttt tagaagcaat gaactataaa
     3121 aaagtaaaca taattggtag tagtggaggc gctcttgttg cattaaatgt tgcacttgag
     3181 agacctgatt tagtgaataa ggtaattgca gatagttttg aaggagaagt tcctctagag
     3241 tcatttgtac aaaatgtgaa aatagagcgt gaagcatcta agcaagatga tggtgcaaaa
     3301 gctttttata tttataatca aggagaaaac tgggaaaaag ttgtagataa tgatacagaa
     3361 gctatttttg aacattataa aactatagga aagttttttc ataagcctct agaaactatg
     3421 caaccagagg tgcttttaac aggaagtaga gaagatgagt ttgtatctct aatatctagt
     3481 gatttttttg aaaatacttt ttcattactt cttgaaaaga ttaaaaatgg taaaatgtat
     3541 ttgtttgata aaggtggtca tcctgcaatt ttatcgaatg gattagattt ttcaaatgta
     3601 gcaaagaaat ttttagagga ataatttaac caaaatttac aataatgaaa actgtaaaat
     3661 ggattgcaaa acttacaaaa gtgagtgtac atatacttca ttattatgat gaaatagtat
     3721 tgttaaaaca aaatattcta atagtcaagt tattacattt gtatatgcaa tatgtataga
     3781 aagagatatc attagattgt aaagttggga ttaaataaca atattaaatt ttatttattc
     3841 agatatttta gcttaactat ataaatgtta gaacaaattt atatagttaa gctgtaggat
     3901 taaataattt agttaaataa gtttattatc tcctcatcag atagactttt taatacacct
     3961 tcattagaaa gttctccatt tataaattga tttataagct cttttttact ttcttgtaat
     4021 tttattattt tttcttctat agtcccttta gcaatcaatt ttataacttg tactgaattt
     4081 ttttgaccaa atctatgagc tctatcacta gcttgatttt ctactgatgg attccaccat
     4141 gggtcaaagt gaattaccat gtcagcagat gtaagattta aaccagttcc gcctgctttt
     4201 aaagatatta aaaaaacttt tttatccata ctattattga actcatctac aagttcaagt
     4261 ctttctttgg cattagtttt accatctata taatggtatt taattttata cttatcaagt
     4321 tccttactta tgttcttaag cacagaagta aattgtgaaa acaataatat tttgtggttt
     4381 tcgtttatac tatccctaag tatttctaaa catgtttcaa tttttgaact ttttttattg
     4441 taatctttta ctactatact tgggtctaaa caaagttgtc ttagtttagt taaataagaa
     4501 aatataacta ttttatcttt ctttagattt ttatctttca ttttatcttg tatatctttt
     4561 gaatatacac tatatatctt tttctgctct ttattcaatt caacaaaaaa gtttttttca
     4621 atcttatctg gaagttcttt cataacttgt tttttacttc ttctaagaat aaaaggtttt
     4681 atcaattttt tcaggttttt aacattatct tctttattta taaacaattc ctgaaacttt
     4741 gctttactat atagatagcc aggcattata aaatcaaata tagaccataa ttctagtaga
     4801 ttattttcca taggtgtacc agtgagtgca aatttatttt ctgcatttat actttttaca
     4861 gactcagtta ctaaagctac tggatttttt atattttgag cttcgtctaa tatacaataa
     4921 tcaaacttta tttcactata tttgtctaaa tcatttctaa gagtaccata tgttgtaagt
     4981 attacatcaa aattttctaa tttcataaaa catttttctc tatctctttt atttccatgt
     5041 atcaataaaa cttttatatc tggagcaaac ttttcaaatt catttttcca attataaatg
     5101 agtgatgtcg gtgtaacaat aagacttttt ttattagata atgataataa aaatgcaata
     5161 gtctgtattg ttttaccaag acccatttca tcagctaata taccaccaaa tttataataa
     5221 tctaaaactt taaaccaatt gaggccattt atttgatagt cacgaaggtt tgcatttaaa
     5281 tttgtgggaa tttctaaatt tatgctatca aaatttctaa atttttcaca tatactgtct
     5341 agttcttttt taccatctat aaactttaaa tttttactac gtattacatc atttatatat
     5401 agagctttat ttttatgaat tttattattt tttgatttat ccattatatc tagattttca
     5461 actaattcaa aaaaatcttt tgtttctctt tctgataaat ctataaagtt tccatcttta
     5521 agtttataaa aagtacgttt ttcttgaaaa gctttcaaaa tatccttgta ctcttttgga
     5581 tttatatcag atatattaaa attaaattct aggtaattct ggttagtctg attgattgaa
     5641 gcttgaattg atgaagcgtt atatattttt ttcaatttaa acttctcaga ataatatata
     5701 tctccaaatt cctttagaga ttctaattgt aaatctaaaa atgtaaatag gtcatggtca
     5761 gttcctttaa acacataatg attattttcc tttgtaaatt gtgaagaagt aagtttattt
     5821 tcaatagtgg cttccttttg tatgttgggg agcacaaatt ttttatcttc atcatcatat
     5881 atatacttta catcacaaca tatgttgcca tcaatcatat caaagtagaa ctcagattta
     5941 aaatcttttg ttatattatt ttttatgtta tcatctaaat gaacttcttg agatatagat
     6001 tttaatctag gaactagcaa tcctaaaaca tccttagaat cctctttatc aaattttaac
     6061 tctttagtct ttgataatat ttgatatatt tttgaataat catgagcttt tttatgtgat
     6121 aataaataga tattgccatc atataaaagt acatcatttt ttttagtaag tggaacaggt
     6181 agtgaatctt tagaatataa gactatttta tcttctatat ttttaaaatc aaaccttaca
     6241 ggtagagtat catttaatat ctttggatga tattcctctt tagaaaaaat aagggtaaaa
     6301 tccttgtact taatagcatt taaaaattgt tttaaagagc ttgcatttat ctccataaat
     6361 ttttttgaat gtgatgaaga aaagttgtat gaaagatttg tcccatattc ttctataata
     6421 tctactaact tctcatcttc atcagcaaaa taatgagtgt tggggttgta agtaaatttc
     6481 ttcccaaaat ctaattcata tccattaagt tttgaatatg caaattcagt aatgtttttt
     6541 aaaatgtaca ttttatcaat tcctatttta aattcagcaa ttgctttatt tgaatccaca
     6601 tttatcaata catctaaatt aaccctttct cttttagtat tgtctaacaa agaaagtaat
     6661 tgcttgctta aatctaagct ggttttagaa tttgtattag aaagcttatc cttatctgca
     6721 cctaatatat ctattagaat aggaggaaca tcttttttat tttttatttg ttttaagctt
     6781 tttatcacaa tagcaactat atgcttacat ataaaaatac ttttgccctt tgattgacag
     6841 tcagcgcaac tacaatcatt ttcaattatc ttaaagtgct ttatatctat agttattgaa
     6901 ttaaaataaa agctataatt atcttcagaa ttgactccac cacgaaatgt caacaggtta
     6961 ttttgtaggt catcaatatc tatgtctata taatcaacta attgattagt ataatatttt
     7021 acacctcttg accatcttga tggttctgta tttcttctta ttagtttata tatcatatct
     7081 attttcatat tattcacctt acctcactgt atatattata atctaaatgc attcaattta
     7141 cactctaaat ttaagactaa aattaaggca gatatgaata gcttttatct atcacaatat
     7201 atgtgtaaat aacaatttac tattagattt ttattgaatt atcttataaa ctatgaatga
     7261 aaaataatta tataaataga ttattaataa atataaaatc ttattattaa aaatattctt
     7321 agaaattaca ctatataaaa tataaagtat gatatttgaa taaaaagaat gtataataag
     7381 tataataatt tgtatttatt attgggaaag gaaaatgtta atatggatag ttatagacaa
     7441 cttaaagcta aaataccctg taaggaaaca ggtatagaaa taaagaggac tttatgtgat
     7501 atttgttctc caggagtaca ttgtggaatt gatgcatatg ttaaagatgg taaagtaata
     7561 aaaatagaag gtacaaaaga acatccaatg aataaagggt tgttatgtac caaaggtctt
     7621 tgcaatagag aatatatcta tagagaagat agaataaaaa cacctctaaa aagaattgga
     7681 aaaagaggtg aaggaaaatt taaaccaata tcatgggatg aagcttatag agaaatagca
     7741 gaaaaattaa atagagtaaa atctgagtat ggagcaaagc atgtagcttt ttttacgggt
     7801 tatggaaagt ggtatagacc ttttttacaa aggtttgcat cttcatttgg ttcacctaat
     7861 tatggtacag aatctagttc atgttcaaca tcagcacaga tggctggaaa tgttgctact
     7921 ggaagaaact ttacaatgca agatatggag aatgcaaaaa cttatttagg gtggggattt
     7981 aatccatact actctaaatt tttaaatagt gtgaatctaa taaaattaaa agaaaaaggt
     8041 ctaaaattta taattgtaga ccctagaata acaccgacaa ctcaaaaact agcagattta
     8101 catttaagaa ttaaacctgg aactgatgga gctttagctc ttggaatggc gaatctattt
     8161 atacaaaaga atttaataga tagagaatac atagaaaagt atgtacatgg atttaatgaa
     8221 tataaagaat atgtaaaatt atttgattta gatactgtaa gtagaattac aggagtttct
     8281 aaagataata tagtaaaagc tgtcgagatg ttgtcacaag gtccattttg tataaatgaa
     8341 agtgcagctc caatagttca tcatcaaaat ggatttcaaa actatagagc aatgatgtct
     8401 ttatccgcta taacaggtaa ttatgataga ataggtggaa acataccaaa acaagattac
     8461 tttgctggta agataggtgg attccaaaca ctagaaaaag agtttgtaaa agaagttcta
     8521 cctaaaaata taaatgaaag aattggtgga gaaagatttc ctctatggaa tgaaatggtg
     8581 actcaatttc aagctatgga tttacctagg caaatagaag aaaagacacc atatgaaata
     8641 agagctttgt tttgtcatgg gataaatgct agaatgtttc ctaattcagg gagacttttt
     8701 aaagcgttga atagtgtaga tttttttgtg aatatagatt tatttatgac agatacatca
     8761 aaatatgcag atatactttt acctgcatgt acatcatttg agagagaaga atgtaagagt
     8821 tatccaggag ggtatattac atataccaaa aaagttattg ataaattata cgattcaaaa
     8881 tcagatgtag aaatactttc agatttagca aatgctatga atatagatga tgatttatta
     8941 aaagcaggtt atgaagcaag tgtaagacat atgtttaaaa atacatgtgt agatgtagat
     9001 aaacttaaag aaagtgattt accattaaaa tgtaaagatt ttaagccata tatagtaggt
     9061 tcatatacaa gagaagggta tgatactagc acttctaggt ttgaattaaa atctacaatt
     9121 attgaaaaat ataaagattt tgggctggat gcactaccaa catatagagg atttaatgat
     9181 aatatagatg atgaatatac tcatttattg acatcaggag caagaatttc aaatgcacta
     9241 cattcaagac ttcatgacat caaactttca agaatattaa aaaatgaagc tagttgtgat
     9301 atttctagct tagatgcaaa agaattgggt gttatcagtg gagattatat aaaaataact
     9361 actaagatag gaagtttgga tgtaaaagtc aatgttactg atagagtctt atataagaat
     9421 atacatatgt atcatggata tagagaagct gatataaata gtattatttg tgataatttt
     9481 gacccttata gtggattccc tgcgtataga agttgtaagt gtaagattga aaaaatgaat
     9541 agataaatgg agagatataa tgaaaagttt atttaaattt aataaagaat tatgtacagc
     9601 atgtggagca tgtttgcttg catgtataga ccaaaatgat aataatatag acaatggtga
     9661 actttttaga catgtattta caatagagga aggtgaaaat atagaatatt tttcattagc
     9721 atgtatacat tgtaatgagc caaaatgttt aggtgtatgt cctaaaaatt gttttaaaaa
     9781 agaagaagga ttcgttgtat tagacaatca aaactgtata gggtgtaaac tttgtgaaaa
     9841 agcttgtgaa tatggagcct taatttatgg aaatgatggt aaggcaaata agtgtaatgg
     9901 ttgtattgag agatataagt gtggtatgga ttcaccttgt gtaatggtat gtcctacagg
     9961 agcattaaaa tttaataaat aaattaaata tagagaatga cttatactta ggtataagat
    10021 atttttacaa aaagctgtat tgagtttgtt ataatgaaaa ctcaatatag cttttttatg
    10081 gatatagttg gatactataa tgtgattctt agtaatagtt ttttgctatt ggacaaagac
    10141 tgtaaaacat attaaactta tgttgttcaa agtcgaagta taatataata actagaaaat
    10201 tggtttatag tgctataaaa gcaaatttag taaggtataa aatcagaggc aatcctttac
    10261 tataatatca atatttggga gttctgttat tgcagagcta ttaaacaatt ataatggtac
    10321 aagtgattca acctttgaaa atgtattata taaaaaatta aaataagatt aaaaaggaga
    10381 gaataaatta tgaaaaaact taaattaatt attatgtttg ccttggtatc agcactgtta
    10441 gttacaggat gttcatcagg aaataataaa aataaagaag aacaaaaagt tataagagtt
    10501 gcaacatcag gaacatatta cccttttgct tttaaagata aagataaact taaagggttt
    10561 gaagtagatt tttgggatga atttgctaaa cgaactaatt gtaaagttga atgggtatta
    10621 actgatttta gtggattatt tggattatta gaagctgata aagcagatgc tgtatctgct
    10681 caacttactg caacacctga aagagagaaa aaatatgctt tttcagatgc ttataattat
    10741 agtggaacaa acattattgt tagagaagat gatactagta taaaatcaat agatgattta
    10801 gttggcaaga aagtaggtgt gggtactgga gcagtagcaa atgaaatatt aaaagaaaaa
    10861 tacccaaatg atgaaataaa aatagtaaat tattcaagtg cgactcttaa agggaattat
    10921 caagacctag aaatgggaag attagatgca gtagttgcgc aggatgttga ggctttaata
    10981 gctataaaag aacaaaaatt aaatcttaaa atgatagaac ctccaattca atttggtgcc
    11041 tgttcttttg cgcttcaaaa aaatgaaaaa ggtgaaaaat ggacaaaaga aattaacgaa
    11101 gtaattgaag agatgtataa agatgggact ttgactaaaa tatctgaaaa ctggctagga
    11161 aaagacatta ctaaggagcc tattaatgag taattttaat tttgaatttt gtctaagtat
    11221 atttccattt ttgattaaag cattgggaat aacaatacta atatctattg ttgcattttt
    11281 tttatcaata ttattaggtg taatacttgc ctttttcaca cagacaaaat caaaagtttt
    11341 acaatacata acaagagtgt atgtttcatt ctttagagga acaccacttt taattcaaat
    11401 atttttcttt tattttggat ttccaatgat attttctttt atgaaagatt gttcacctta
    11461 tttagcaata gtaatttgtt taggtgtaaa ttcatctgca tatatggctg aaattatacg
    11521 agcatctatt gagagtgttg ataaaggaca acaggaagca tgttatgctt ttgggttaag
    11581 taaatatcag tcaatggtta aaataattct acctcaagca gctacatctg cagtacctcc
    11641 tattgtaagc tgtacactgg acataattaa aggttcttct ttaggtttaa ctataggaat
    11701 acaagattta atgggagtag ctcaagtaga ggctgcttca agttttaaat attttgagat
    11761 atatatgata acgatattaa tttactgggc agtatctata atattgagta atatacaaag
    11821 caaagttgaa aaaagaataa gaagagcata ttagatttca atatttaaaa atgggatgat
    11881 atagatatat tattacttgt aaataaattt ttaattttag aaaaataaac ttagtaatct
    11941 aaattattga gaaaatatag tatcaaaatg gactgtataa tcaagttaaa aaatagtttt
    12001 tctattgaaa aaataaataa aattctattg taatttaata tgcgataaag ttttataaaa
    12061 aacaacatta agctaggggg acttatttta tggcttttaa tatgaaatat tttttagaat
    12121 tatttccaac aataatgaaa tcgttcaatg taactgtgat tttggcaata agttcattag
    12181 tattttcatt aattataggt acaatagtag cgttatcatc ttattacaaa gtgaaagtat
    12241 tgaatcaaat atgtaaagta tatgtatcta tttttagagg tacacctctt atgccacagt
    12301 tattcttttt atattttgga ctagcatata tgagtgattt tgttaaaaat atggacccag
    12361 tatttgcaac atctatagta cttagtttaa atatgggagc ttatatgtct gaaacgataa
    12421 gggcatctat actttcaatt gatacaggtc agatagaagc agcatatgca atgggattaa
    12481 caaatttaca aacaatgaaa aggatagtga taccacaggc cgtaagagtt gcactgccat
    12541 cattattcaa taattttata gatttaatta aagggtcttc tgtagctttt gttgttggag
    12601 taaatgatat aatgggtgct gccaaatcac aaggagcgtt gagttttaag ttttttgaag
    12661 tgtatggagc agttatggta atttactggt gtataataac tcctttaggt tgggggcaaa
    12721 aaaaattaga aaagaaaata agcaattatt aagttattaa gaaaatacat aaaagtattt
    12781 ttatataaaa aatggtgtga ggagaagaga tatgataaaa agaaatatta taaaatgttt
    12841 agtggcagtt ttatcgttaa cgtttgtaat tactggttgt tcaaaaaaag aggaagtaaa
    12901 gaatgaaaaa gttataactg tagcttcatc taattcagct gacccatatt cttatgttga
    12961 taatggtgag cataagggtt ttgaagttga catgtggaaa gagattggta aaagaagtgg
    13021 atataagata aaaatggaac caacaggttt tagttctata tttggtatgt tagattctgg
    13081 taaagttgat gtggcagcca acttctttgg aatgtctaaa gaaagattag aaaaatacga
    13141 tgcttctata ccttatggtt ctgattctgt gtgtatagct gtaaaagatg gaaataacga
    13201 aattaataag cttgaagatt taaagggaaa agttgtagca gtttcagaag gttctcaagg
    13261 tcaacaggtt gcaactagtg ttaataaaga taatttgttt caagaaaagg tttacggtga
    13321 tggaactagt ggtcttcaag atttagattt gggaagagtt agtgcatgga ttgatgcaga
    13381 gcttactatt gtgggagacg ctaaaaaagc taatatgaaa gtaagagtat tagataaaaa
    13441 attatcagct actaatatag catacttctt taagaaaaac gatgataaat ctaaaacgat
    13501 aaaagaagat gtaaacaaag caatagaaga aatgcttgca gatggaacag tgaaaaaaat
    13561 atctgaaaaa tggtttggaa tggatgtaag tgctgatata caaaaataaa tactttaaaa
    13621 ttaaaatgta aaactgtgat aactatagat aagtatacta aatttatcta tagttatctg
    13681 tgtattacaa tgtatttaga ttagtcttta taaatcaaaa tgagttatgg aggtattgca
    13741 aatgattgaa actaaaataa aatccattgc actaaaaaat agagaaaaaa ttataaaaat
    13801 aagacgacag atacacagta atccagagtt agcatttaaa gaatataaaa catctaaact
    13861 tataaaagaa gagctaaata aacttaatat agaatacata aatattgctg gtacaggagt
    13921 attagctact ataaaaggaa aaaataatgg tggaaaaact atattactca gagcggatat
    13981 ggatgctctt ccaatcaaag aggaaaatga tttagaattt aaatcaataa atgataatat
    14041 gcatgcttgt gggcatgatg cacatgtttc atggttgtta ggaacagcaa tgattttaaa
    14101 tgacataaaa gaagaattga atggaaatgt aaaattacta tttcaacctg gcgaagaaaa
    14161 aggtggttct gatattgtaa ttaaagaaaa tgtacttgaa ggtgtggatg cattagcgac
    14221 tggtcattgt tggccaacta ttgagtcagg aaaaattgga atcgctagaa attgtgctat
    14281 ggcagcgact aatacttttg aaataacaat aattggcaag ggtgggcatg gagcagagcc
    14341 tcataattgt atagacccaa ttgcagttgg aaatgcagta tattcatcca ttcaacagat
    14401 agtttcaaga aaaattgacc cagttgtacc tgtagtagtg tctgtttgtt cttttaattc
    14461 tggtgtttct aaaaatataa taccagatgt atgtacactt caagggacta ttagagcgat
    14521 aagcaaggaa caagtaattg aagtaagtaa aattctagaa tatatagtaa aaaatgtatg
    14581 taaagcacat ggagcagatt gcaaatttga aaagagtaca ggaggagatg ctgttataaa
    14641 tgacaaaaac atgatagaga taggaagaga aagtgcttgc aaaatacttg gagctgaaaa
    14701 tgttgaaata attgattttc ctgcaatgac aggtgaggat tttgctattt atatgaaaga
    14761 aaaacctggt ttatttatgt atataggtgt aggagataaa gaaaaaaata taaattacag
    14821 attgcatagt aacaagttta atatagatga aaaatgtctt agtatagcac cttcattatt
    14881 ttcacaactt acagtagatt atttatgtca actatagagt acattcataa aaatatattt
    14941 agcctatttt taaatttaat gctagtatat taattttgat gtagaacata ttatttatta
    15001 tatttattta aaaaggtgga taacaatgat aaaagtagaa aatttacata aaagttttaa
    15061 agggacagaa gttcttaaag gtataaattt agagataagt caaagtgaag tagtagctat
    15121 acttggatca tctggaacag gtaaatctac gttacttaga tgtttaaatt atttagttga
    15181 gcctacaaaa ggaaagataa tgattggtga tgtaaaagta gatgtagaaa aagcaacaaa
    15241 aaaagatata accaatttaa gaaaacatac atctatggtg tttcaaaatt ataacttatt
    15301 taaaaataaa acagcattag aaaatgtaat ggaggcattg atagtagttc ataaaaagag
    15361 taagaaagaa gctagagaaa tatctttaaa attaatagat aaagtaggta tgttggatag
    15421 gaaagatttt tatccatcaa agttgtctgg gggacagcaa caaaggatag gtatagcgag
    15481 agcgatggca gtaaatccaa atgtaatatt atttgatgag cctacatctg cacttgaccc
    15541 agaacttgtt ggagaagttt taagcgttat aaaatctctt gcaaaagaag gtataacgat
    15601 gcttattgta actcacgaaa taaattttgc aaaagaagtt gctgataaaa ttatatttat
    15661 ggataatggt gtaatagctg aagaaggaac tcctgatgaa atatttaata atcctaaaaa
    15721 tgaaagaaca gcaaaatttt taaatatcat taggaaagaa gaagtattta gttaaaagtg
    15781 tataaattaa gcattagaag atatgtaaga tacccccatt aaatttataa gttagataat
    15841 aaatttaatg ggagtatatt tttattatta gatttattat ttaatttaaa attagaaatg
    15901 taactatttg aaaattcttt ttaaaagtat atcaaaatat caaatacata aaaaaataat
    15961 atttgacaaa gtatcatatg tgtttacaaa atcaacttta tggagttata tagtatagga
    16021 attacaatga atatactaaa
//
LOCUS       DAEOTL010000092        15296 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEOTL010000092 DAEOTL010000000
VERSION     DAEOTL010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.093"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            243..797
                     /gene="tcdR"
                     /locus_tag="KRH82_003256"
     CDS             243..797
                     /gene="tcdR"
                     /locus_tag="KRH82_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBG8656521.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1115..8215
                     /gene="tcdB"
                     /locus_tag="KRH82_003257"
                     /gene_synonym="toxB"
     CDS             1115..8215
                     /gene="tcdB"
                     /locus_tag="KRH82_003257"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBG8656522.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8337..8837
                     /gene="tcdE"
                     /locus_tag="KRH82_003258"
     CDS             8337..8837
                     /gene="tcdE"
                     /locus_tag="KRH82_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBG8656523.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            8916..9077
                     /locus_tag="KRH82_003259"
     CDS             8916..9077
                     /locus_tag="KRH82_003259"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656524.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYIDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9166..9348
                     /locus_tag="KRH82_003260"
     CDS             9166..9348
                     /locus_tag="KRH82_003260"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656525.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9565..>15296
                     /gene="tcdA"
                     /locus_tag="KRH82_003261"
                     /gene_synonym="toxA"
     CDS             9565..>15296
                     /gene="tcdA"
                     /locus_tag="KRH82_003261"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021414120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBG8656526.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANT"
BASE COUNT         6198 a         1573 c         2390 g         5135 t
ORIGIN      
        1 tttactttaa taaaatgatt tgtttttaca atactttatt aatataaagt ttattgctaa
       61 aatactttat ttattagaaa aagattacta attaattatt aaaattaatg tattcataat
      121 gcatattttc atataaaatt taatttattt gccgattata taattataat gactgattta
      181 attccgatgt tgtcaaaatt ttcaaataaa tcatcattat aaatataaga gaggatgatt
      241 ttatgcaaaa gtctttttat gaattaattg ttttagcaag aaataactca gtagatgatt
      301 tgcaagaaat tttatttatg tttaagccat tagtaaaaaa acttagtaga gttttacatt
      361 atgaagaggg agaaacagat ttaataatat tttttattga attaataaaa aatattaaat
      421 taagtagctt ttcagaaaaa agcgatgcta ttatagtcaa atatattcat aaatcattac
      481 tgaataagac ttttgagttg tctagaagat attctaaaat gaagtttaat tttgtagaat
      541 ttgatgaaaa tatcttaaat atgaaaaata attatcaaag taagtctgtt tttgaggaag
      601 atatttgttt tttcgaatat attttgaaag aattatctgg tattcaaaga aaagttattt
      661 tttataaata tttaaaagga tattctgata gagaaatatc agtgaaatta aaaatatcta
      721 gacaagctgt taataaggct aaaaatagag catttaaaaa aataaaaaaa gactatgaaa
      781 attattttaa cttgtaatta atgagcttaa agaaatattt acaatagaaa tcaaatttta
      841 gaattaactt tattgtaaaa tcaataactt aatctaagaa tatcttaatt tttatatttt
      901 atatagaaca aagtttacat atttatttca gacaacgtct ttattcaatc gaagagcaaa
      961 ttaatcaact gagtgtctta aatttaaaat gttaggaagt gaatgtatat gaaaacctaa
     1021 gtagatatta gtatatttta taaatagaaa ggaggatata taaaagagtt ttagcattta
     1081 gatgtaaaaa tattatagta aaggagaaaa ttttatgagt ttagttaata gaaaacagtt
     1141 agaaaaaatg gcaaatgtaa gatttcgtac tcaagaagat gaatatgttg caatattgga
     1201 tgctttagaa gaatatcata atatgtcaga gaatactgta gtcgaaaaat atttaaaatt
     1261 aaaagatata aatagtttaa cagatattta tatagataca tataaaaaat ctggtagaaa
     1321 taaagcctta aaaaaattta aggaatatct agttacagaa gtattagagc taaagaataa
     1381 taatttaact ccagttgaga aaaatttaca ttttgtttgg attggaggtc aaataaatga
     1441 cactgctatt aattatataa atcaatggaa agatgtaaat agtgattata atgttaatgt
     1501 tttttatgat agtaatgcat ttttgataaa cacattgaaa aaaactgtag tagaatcagc
     1561 aataaatgat acacttgaat catttagaga aaacttaaat gaccctagat ttgactataa
     1621 taaattcttc agaaaacgta tggaaataat ttatgataaa cagaaaaatt tcataaacta
     1681 ctataaagct caaagagaag aaaatcctga acttataatt gatgatattg taaagacata
     1741 tctttcaaat gagtattcaa aggagataga tgaacttaat acctatattg aagaatcctt
     1801 aaataaaatt acacagaata gtggaaatga tgttagaaac tttgaagaat ttaaaaatgg
     1861 agagtcattc aacttatatg aacaagagtt ggtagaaagg tggaatttag ctgctgcttc
     1921 tgacatatta agaatatctg cattaaaaga aattggtggt atgtatttag atgttgatat
     1981 gttaccagga atacaaccag acttatttga gtctatagag aaacctagtt cagtaacagt
     2041 ggatttttgg gaaatgacaa agttagaagc tataatgaaa tacaaagaat atataccaga
     2101 atatacctca gaacattttg acatgttaga cgaagaagtt caaagtagtt ttgaatctgt
     2161 tctagcttct aagtcagata aatcagaaat attctcatca cttggtgata tggaggcatc
     2221 accactagaa gttaaaattg catttaatag taagggtatt ataaatcaag ggctaatttc
     2281 tgtgaaagac tcatattgta gcaatttaat agtaaaacaa atcgagaata gatataaaat
     2341 attgaataat agtttaaatc cagctattag cgaggataat gattttaata ctacaacgaa
     2401 tacctttatt gatagtataa tggctgaagc taatgcagat aatggtagat ttatgatgga
     2461 actaggaaag tatttaagag ttggtttctt cccagatgtt aaaactacta ttaacttaag
     2521 tggccctgaa gcatatgcgg cagcttatca agatttatta atgtttaaag aaggcagtat
     2581 gaatatccat ttgatagaag ctgatttaag aaactttgaa atctctaaaa ctaatatttc
     2641 tcaatcaact gaacaagaaa tggctagctt atggtcattt gacgatgcaa gagctaaagc
     2701 tcaatttgaa gaatataaaa ggaattattt tgaaggttct cttggtgaag atgataatct
     2761 tgatttttct caaaatatag tagttgacaa ggagtatctt ttagaaaaaa tatcttcatt
     2821 agcaagaagt tcagagagag gatatataca ctatattgtt cagttacaag gagataaaat
     2881 tagttatgaa gcagcatgta acttatttgc aaagactcct tatgatagtg tactatttca
     2941 gaaaaatata gaagattcag aaattgcata ttattataat cctggagatg gtgaaataca
     3001 agaaatagac aagtataaaa ttccaagtat aatttctgat agacctaaga ttaaattaac
     3061 atttattggt catggtaaag atgaatttaa tactgatata tttgcaggtt ttgatgtaga
     3121 ttcattatcc acagaaatag aagcagcaat agatttagct aaagaggata tttctcctaa
     3181 gtcaatagaa ataaatttat taggatgtaa tatgtttagc tactctatca acgtagagga
     3241 gacttatcct ggaaaattat tacttaaagt taaagataaa atatcagaat taatgccatc
     3301 tataagtcaa gactctatta tagtaagtgc aaatcaatat gaagttagaa taaatagtga
     3361 aggaagaaga gaattattgg atcattctgg tgaatggata aataaagaag aaagtattat
     3421 aaaggatatt tcatcaaaag aatatatatc atttaatcct aaagaaaata aaattacagt
     3481 aaaatctaaa aatttacctg agctatctac attattacaa gaaattagaa ataattctaa
     3541 ttcaagtgat attgaactag aagaaaaagt aatgttaaca gaatgtgaga taaatgttat
     3601 ttcaaatata gatacgcaaa ttgttgagga aaggattgaa gaagctaaga atttaacttc
     3661 tgactctatt aattatataa aagatgaatt taaactaata gaatctattt ctgatgcact
     3721 atgtgactta aaacaacaga atgaattaga agattctcat tttatatctt ttgaggacat
     3781 atcagagact gatgagggat ttagtataag atttattaat aaagaaactg gagaatctat
     3841 atttgtagaa actgaaaaaa caatattctc tgaatatgct aatcatataa ctgaagagat
     3901 ttctaagata aaaggtacta tatttgatac tgtaaatggt aagttagtaa aaaaagtaaa
     3961 tttagatact acacacgaag taaatacttt aaatgctgca ttttttatac aatcattaat
     4021 agaatataat agttctaaag aatctcttag taatttaagt gtagcaatga aagtccaagt
     4081 ttacgctcaa ttatttagta ctggtttaaa tactattaca gatgcagcca aagttgttga
     4141 attagtatca actgcattag atgaaactat agacttactt cctacattat ctgaaggatt
     4201 acctataatt gcaactatta tagatggtgt aagtttaggt gcagcaatca aagagctaag
     4261 tgaaacgagt gacccattat taagacaaga aatagaagct aagataggta taatggcagt
     4321 aaatttaaca acagctacaa ctgcaatcat tacttcatct ttgggggtag ctagtggatt
     4381 tagtatactt ttagttcctt tagcaggaat ttcagcaggt ataccaagct tagtaaacaa
     4441 tgaacttgta cttcgagata aggcaacaaa ggttgtagat tattttaaac atgtttcatt
     4501 agttgaaact gaaggagtat ttactttatt agatgataaa ataatgatgc cacaagatga
     4561 tttagtgata tcagaaatag attttaataa taattcaata gttttaggta aatgtgaaat
     4621 ctggagaatg gaaggtggtt caggtcatac tgtaactgat gatatagatc acttcttttc
     4681 agcaccatca ataacatata gagagccaca cttatctata tatgacgtat tggaagtaca
     4741 aaaagaagaa cttgatttgt caaaagattt aatggtatta cctaatgctc caaatagagt
     4801 atttgcttgg gaaacaggat ggacaccagg tttaagaagc ttagaaaatg atggcacaaa
     4861 actgttagac cgtataagag ataactatga aggtgagttt tattggagat attttgcttt
     4921 tatagctgat gctttaataa caacattaaa accaagatat gaagatacta atataagaat
     4981 aaatttagat agtaatacta gaagttttat agttccaata ataactacag aatatataag
     5041 agaaaaatta tcatattctt tctatggttc aggaggaact tatgcattgt ctctttctca
     5101 atataatatg ggtataaata tagaattaag tgaaagtgat gtttggatta tagatgttga
     5161 taatgttgtg agagatgtaa ctatagaatc tgataaaatt aaaaaaggtg atttaataga
     5221 aggtatttta tctacactaa gtattgaaga gaataaaatt atcttaaata gccatgagat
     5281 taatttttct ggtgaggtaa atggaagtaa tggatttgtt tctttaacat tttcaatttt
     5341 agaaggaata aatgcaatta tagaagttga tttattatct aaatcatata aattacttat
     5401 ttctggcgaa ttaaaaatat tgatgttaaa ttcaaatcat attcaacaga aaatagatta
     5461 tataggattc aatagcgaat tacagaaaaa tataccatat agctttgtag atagtgaagg
     5521 aaaagagaat ggttttatta atggttcaac aaaagaaggt ttatttgtat ctgaattacc
     5581 tgatgtagtt cttataagta aggtttatat ggatgatagt aagccttcat ttggatatta
     5641 tagtaataat ttgaaagatg tcaaagttat aactaaagat aatgttaata tattaacagg
     5701 ttattatctt aaggatgata taaaaatctc tctttctttg actctacaag atgaaaaaac
     5761 tataaagtta aatagtgtgc atttagatga aagtggagta gctgagattt tgaagttcat
     5821 gaatagaaaa ggtaatacaa atacttcaga ttctttaatg agctttttag aaagtatgaa
     5881 tataaaaagt attttcgtta atttcttaca atctaatatt aagtttatat tagatgctaa
     5941 ttttataata agtggtacta cttctattgg ccaatttgag tttatttgtg atgaaaatga
     6001 taatatacaa ccatatttca ttaagtttaa tacactagaa actaattata ctttatatgt
     6061 aggaaataga caaaatatga tagtggaacc aaattatgat ttagatgatt ctggagatat
     6121 atcttcaact gttatcaatt tctctcaaaa gtatctttat ggaatagaca gttgtgttaa
     6181 taaagttgta atttcaccaa atatttatac agatgaaata aatataacgc ctgtatatga
     6241 aacaaataat acttatccag aagttattgt attagatgca aattatataa atgaaaaaat
     6301 aaatgttaat atcaatgatc tatctatacg atatgtatgg agtaatgatg gtaatgattt
     6361 tattcttatg tcaactagtg aagaaaataa ggtgtcacaa gttaaaataa gattcgttaa
     6421 tgtttttaaa gataagactt tggcaaataa gctatctttt aactttagtg ataaacaaga
     6481 tgtacctgta agtgaaataa tcttatcatt tacaccttca tattatgagg atggattgat
     6541 tggctatgat ttgggtctag tttctttata taatgagaaa ttttatatta ataactttgg
     6601 aatgatggta tctggattaa tatatattaa tgattcatta tattatttta aaccaccagt
     6661 aaataatttg ataactggat ttgtgactgt aggcgatgat aaatactact ttaatccaat
     6721 taatggtgga gctgcttcaa ttggagagac aataattgat gacaaaaatt attatttcaa
     6781 ccaaagtgga gtgttacaaa caggtgtatt tagtacagaa gatggattta aatattttgc
     6841 cccagctaat acacttgatg aaaacctaga aggagaagca attgatttta ctggaaaatt
     6901 aattattgac gaaaatattt attattttga tgataattat agaggagctg tagaatggaa
     6961 agaattagat ggtgaaatgc actattttag cccagaaaca ggtaaagctt ttaaaggtct
     7021 aaatcaaata ggtgattata aatactattt caattctgat ggagttatgc aaaaaggatt
     7081 tgttagtata aatgataata aacactattt tgatgattct ggtgttatga aagtaggtta
     7141 cactgaaata gatggcaagc atttctactt tgctgaaaac ggagaaatgc aaataggagt
     7201 atttaataca gaagatggat ttaaatattt tgctcatcat aatgaagatt taggaaatga
     7261 agaaggtgaa gaaatctcat attctggtat attaaatttc aataataaaa tttactattt
     7321 tgatgattca tttacagctg tagttggatg gaaagattta gaggatggtt caaagtatta
     7381 ttttgatgaa gatacagcag aagcatatat aggtttgtca ttaataaatg atggtcaata
     7441 ttattttaat gatgatggaa ttatgcaagt tggatttgtc actataaatg ataaagtctt
     7501 ctacttctct gactctggaa ttatagaatc tggagtacaa aacatagatg acaattattt
     7561 ctatatagat gataatggta tagttcaaat tggtgtattt gatacttcag atggatataa
     7621 atattttgca cctgctaata ctgtaaatga taatatttac ggacaagcag ttgaatatag
     7681 tggtttagtt agagttgggg aagatgtata ttattttgga gaaacatata caattgagac
     7741 tggatggata tatgatatgg aaaatgaaag tgataaatat tatttcaatc cagaaactaa
     7801 aaaagcatgc aaaggtatta atttaattga tgatataaaa tattattttg atgagaaggg
     7861 cataatgaga acgggtctta tatcatttga aaataataat tattacttta atgagaatgg
     7921 tgaaatgcaa tttggttata taaatataga agataagatg ttctattttg gtgaagatgg
     7981 tgtcatgcag attggagtat ttaatacacc agatggattt aaatactttg cacatcaaaa
     8041 tactttggat gagaattttg agggagaatc aataaactat actggttggt tagatttaga
     8101 tgaaaagaga tattatttta cagatgaata tattgcagca actggttcag ttattattga
     8161 tggtgaggag tattattttg atcctgatac agctcaatta gtgattagtg aatagataaa
     8221 aatatgttaa atatatcctc ttatacttaa atatataaaa ataaacaaaa tgatacacta
     8281 cataaagtgt tctatctaat atgaagattt accaataaaa aggtggacta tgatgaatgc
     8341 acagtagttc acctttttat atttctaatg gtaacaaaat atttttttat ataaacctag
     8401 gaggcgttat gaatatgaca atatcttttt tatcagagca tatatttata aagttagtaa
     8461 ttttaactat atcatttgat acattattag gatgtttaag tgcaataaaa agtcgtaaat
     8521 ttaattctag ttttggaata gatggaggaa tcagaaaagt agcaatgata gcatgtatat
     8581 tttttttatc agtagttgac attcttacaa agtttaactt tttatttatg ttaccacaag
     8641 attgtatcaa ttttttaaga ctaaaacatc ttggaatatc tgaatttttc tctattttat
     8701 ttattttata tgaaagtgta agtatattaa aaaatatgtg cttatgtgga ttaccagtac
     8761 ctaagagatt aaaggaaaaa atagcaattt tactagatgc aatgacagat gaaatgaatg
     8821 ctaaggatga aaagtaagta atggtagata taataaagat attaacaaat aaaaagtgtt
     8881 atccaaataa gaatagctga aagttatcat aattcatgaa actaataatg aaaacgaggg
     8941 agcagatgcc aagagacaca caagtattaa atacatataa tttcgaagca agtgttcatt
     9001 actatataga tgacaaggta gtatatcaaa cattggttca caaagatggt gcatggtcag
     9061 ttggtaaaat ctattaagct acattagtta cagatatcac aaactataat agttaaacat
     9121 agaaatatgt gtaaattgtg atggaaatta ttcaaaaaca caaaaatacg tgatgaagga
     9181 caaaatgata tagaaaataa gtatcaaacc ttaataaatg atttaattga tagtttaaaa
     9241 gttataggaa aaatatataa agaaataaaa acattaaaaa aatataagat atgtttacaa
     9301 attactatca gacaatctcc ttatctaata gaagagtcaa ttaactaatt gagtatcttt
     9361 aaattgaaat gttaggaagt gatttaaata tgaaaactta aattataaaa aatcaatatt
     9421 aatttatttt taaaaaatag aaaggagtgt ataagattta ttttcaaagt ttaaaaacaa
     9481 gaaaatcaat ttaaatttca gaaggaataa atgtggttat agaagtggat ttattatcaa
     9541 aaataataat actaggaggt ttttatgtct ttaatatcta aagaagagtt aataaaactc
     9601 gcatatagca ttagaccaag agaaaatgag tataaaacta tactaactaa tttagacgaa
     9661 tataataagt taactacaaa caataatgaa aataaatatt tacaattaaa aaaactaaat
     9721 gaatcaattg atgtttttat gaataaatat aaaacttcaa gcagaaatag agcactctct
     9781 aatctaaaaa aagatatatt aaaagaagta attcttatta aaaattccaa tacaagccct
     9841 gtagaaaaaa atttacattt tgtatggata ggtggagaag tcagtgatat tgctcttgaa
     9901 tacataaaac aatgggctga tattaatgca gaatataata ttaaactgtg gtatgatagt
     9961 gaagcattct tagtaaatac actaaaaaag gctatagttg aatcttctac cactgaagca
    10021 ttacagctac tagaggaaga gattcaaaat cctcaatttg ataatatgaa attttacaaa
    10081 aaaaggatgg aatttatata tgatagacaa aaaaggttta taaattatta taaatctcaa
    10141 atcaataaac ctacagtacc tacaatagat gatattataa agtctcatct agtatctgaa
    10201 tataatagag atgaaactgt attagaatca tatagaacaa attctttgag aaaaataaat
    10261 agtaatcatg ggatagatat cagggctaat agtttgttta cagaacaaga gttattaaat
    10321 atttatagtc aggagttgtt aaatcgtgga aatttagctg cagcatctga catagtaaga
    10381 ttattagccc taaaaaattt tggcggagta tatttagatg ttgatatgct tccaggtatt
    10441 cactctgatt tatttaaaac aatatctaga cctagctcta ttggactaga ccgttgggaa
    10501 atgataaaat tagaggctat tatgaagtat aaaaaatata taaataatta tacatcagaa
    10561 aactttgata aacttgatca acaattaaaa gataatttta aactcattat agaaagtaaa
    10621 agtgaaaaat ctgagatatt ttctaaatta gaaaatttaa atgtatctga tcttgaaatt
    10681 aaaatagctt tcgctttagg cagtgttata aatcaagcct tgatatcaaa acaaggttca
    10741 tatcttacta acctagtaat agaacaagta aaaaatagat atcaattttt aaaccaacac
    10801 cttaacccag ccatagagtc tgataataac ttcacagata ctactaaaat ttttcatgat
    10861 tcattattta attcagctac cgcagaaaac tctatgtttt taacaaaaat agcaccatac
    10921 ttacaagtag gttttatgcc agaagctcgc tccacaataa gtttaagtgg tccaggagct
    10981 tatgcgtcag cttactatga tttcataaat ttacaagaaa atactataga aaaaacttta
    11041 aaagcatcag atttaataga atttaaattc ccagaaaata atctatctca attgacagaa
    11101 caagaaataa atagtctatg gagctttgat caagcaagtg caaaatatca atttgagaaa
    11161 tatgtaagag attatactgg tggatctctt tctgaagaca atggggtaga ctttaataaa
    11221 aatactgccc tcgacaaaaa ctatttatta aataataaaa ttccatcaaa caatgtagaa
    11281 gaagctggaa gtaaaaatta tgttcattat atcatacagt tacaaggaga tgatataagt
    11341 tatgaagcaa catgcaattt attttctaaa aatcctaaaa atagtattat tatacaacga
    11401 aatatgaatg aaagtgcaaa aagctacttt ttaagtgatg atggagaatc tattttagaa
    11461 ttaaataaat ataggatacc tgaaagatta aaaaataagg aaaaagtaaa agtaaccttt
    11521 attggacatg gtaaagatga attcaacaca agcgaatttg ctagattaag tgtagattca
    11581 ctttccaatg agataagttc atttttagat accataaaat tagatatatc acctaaaaat
    11641 gtagaagtaa acttacttgg atgtaatatg tttagttatg attttaatgt tgaagaaact
    11701 tatcctggga agttgctatt aagtattatg gacaaaatta cttccacttt acctgatgta
    11761 aataaaaatt ctattactat aggagcaaat caatatgaag taagaattaa tagtgaggga
    11821 agaaaagaac ttctggctca ctcaggtaaa tggataaata aagaagaagc tattatgagc
    11881 gatttatcta gtaaagaata catttttttt gattctatag ataataagct aaaagcaaag
    11941 tccaagaata ttccaggatt agcatcaata tcagaagata taaaaacatt attacttgat
    12001 gcaagtgtta gtcctgatac aaaatttatt ttaaataatc ttaagcttaa tattgaatct
    12061 tctattggtg attacattta ttatgaaaaa ttagagcctg ttaaaaatat aattcacaat
    12121 tctatagatg atttaataga tgagttcaat ctacttgaaa atgtatctga tgaattatat
    12181 gaattaaaaa aattaaataa tctagatgag aagtatttaa tatcttttga agatatctca
    12241 aaaaataatt caacttactc tgtaagattt attaacaaaa gtaatggtga gtcagtttat
    12301 gtagaaacag aaaaagaaat tttttcaaaa tatagcgaac atattacaaa agaaataagt
    12361 actataaaga atagtataat tacagatgtt aatggtaatt tattggataa tatacagtta
    12421 gatcatactt ctcaagttaa tacattaaac gcagcattct ttattcaatc attaatagat
    12481 tatagtagca ataaagatgt actgaatgat ttaagtacct cagttaaggt tcaactttat
    12541 gctcaactat ttagtacagg tttaaatact atatatgact ctatccaatt agtaaattta
    12601 atatcaaatg cagtaaatga tactataaat gtactaccta caataacaga ggggatacct
    12661 attgtatcta ctatattaga cggaataaac ttaggtgcag caattaagga attactagac
    12721 gaacatgacc cattactaaa aaaagaatta gaagctaagg tgggtgtttt agcaataaat
    12781 atgtcattat ctatagctgc aactgtagct tcaattgttg gaataggtgc tgaagttact
    12841 attttcttat tacctatagc tggtatatct gcaggaatac cttcattagt taataatgaa
    12901 ttaatattgc atgataaggc aacttcagtg gtaaactatt ttaatcattt gtctgaatct
    12961 aaaaaatatg gccctcttaa gacagaagat gataaaattt tagttcctat tgatgattta
    13021 gtaatatcag aaatagattt taataataat tcgataaaac taggaacatg taatatatta
    13081 gcaatggagg ggggatcagg acacacagtg actggtaata tagatcactt tttctcatct
    13141 ccatctataa gttctcatat tccttcatta tcaatttatt ctgcaatagg tatagaaaca
    13201 gaaaatctag atttttcaaa aaaaataatg atgttaccta atgctccttc aagagtgttt
    13261 tggtgggaaa ctggagcagt tccaggttta agatcattgg aaaatgacgg aactagatta
    13321 cttgattcaa taagagattt atacccaggt aaattttact ggagattcta tgcttttttc
    13381 gattatgcaa taactacatt aaaaccagtt tatgaagaca ctaatattaa aattaaacta
    13441 gataaagata ctagaaactt cataatgcca actataacta ctaacgaaat tagaaacaaa
    13501 ttatcttatt catttgatgg agcaggagga acttactctt tattattatc ttcatatcca
    13561 atatcaacga atataaattt atctaaagat gatttatgga tatttaatat tgataatgaa
    13621 gtaagagaaa tatctataga aaatggtact attaaaaaag gaaagttaat aaaagatgtt
    13681 ttaagtaaaa ttgatataaa taaaaataaa cttattatag gcaatcaaac aatagatttt
    13741 tcaggcgata tagataataa agatagatat atattcttga cttgtgagtt agatgataaa
    13801 attagtttaa taatagaaat aaatcttgtt gcaaaatctt atagtttgtt attgtctggg
    13861 gataaaaatt atttgatatc caatttatct aatactattg agaaaatcaa tactttaggc
    13921 ctagatagta aaaatatagc gtacaattac actgatgaat ctaataataa atattttgga
    13981 gctatatcta aaacaagtca aaaaagcata atacattata aaaaagacag taaaaatata
    14041 ttagaatttt ataatgacag tacattagaa tttaacagta aagattttat tgctgaagat
    14101 ataaatgtat ttatgaaaga tgatattaat actataacag gaaaatacta tgttgataat
    14161 aatactgata aaagtataga tttctctatt tctttagtta gtaaaaatca agtaaaagta
    14221 aatggattat atttaaatga atccgtatac tcatcttacc ttgattttgt gaaaaattca
    14281 gatggacacc ataatacttc taattttatg aatttatttt tggacaatat aagtttctgg
    14341 aaattgtttg ggtttgaaaa tataaatttt gtaatcgata aatactttac ccttgttggt
    14401 aaaactaatc ttggatatgt agaatttatt tgtgacaata ataaaaatat agatatatat
    14461 tttggtgaat ggaaaacatc gtcatctaaa agcactatat ttagcggaaa tggtagaaat
    14521 gttgtagtag agcctatata taatcctgat acgggtgaag atatatctac ttcactagat
    14581 ttttcctatg aacctctcta tggaatagat agatatatca ataaagtatt gatagcacct
    14641 gatttatata caagtttaat aaatattaat accaattatt attcaaatga gtactaccct
    14701 gagattatag ttcttaaccc aaatacattc cacaaaaaag taaatataaa tttagatagt
    14761 tcttcttttg agtataaatg gtctacagaa ggaagtgact ttattttagt tagatactta
    14821 gaagaaagta ataaaaaaat attacaaaaa ataagaatca aaggtatctt atctaatact
    14881 caatcattta ataaaatgag tatagatttt aaagatatta aaaaactatc attaggatat
    14941 ataatgagta attttaaatc atttaattct gaaaatgaat tagatagaga tcatttagga
    15001 tttaaaataa tagataataa aacttattac tatgatgaag atagtaaatt agttaaagga
    15061 ttaatcaata taaataattc attattctat tttgatccta tagaatttaa cttagtaact
    15121 ggatggcaaa ctatcaatgg taaaaaatat tattttgata taaatactgg agcagcttta
    15181 actagttata aaattattaa tggtaaacac ttttatttta ataatgatgg tgtgatgcag
    15241 ttgggagtat ttaaaggacc tgatggattt gaatattttg cacctgccaa tactca
//
LOCUS       DAEOTL010000093        14971 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEOTL010000093 DAEOTL010000000
VERSION     DAEOTL010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.094"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(43..579)
                     /locus_tag="KRH82_003262"
     CDS             complement(43..579)
                     /locus_tag="KRH82_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBG8656527.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(597..1910)
                     /locus_tag="KRH82_003263"
     CDS             complement(597..1910)
                     /locus_tag="KRH82_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBG8656528.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2265..2705
                     /locus_tag="KRH82_003264"
     CDS             2265..2705
                     /locus_tag="KRH82_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBG8656529.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2890..3078)
                     /locus_tag="KRH82_003265"
     CDS             complement(2890..3078)
                     /locus_tag="KRH82_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656530.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTVIKNSNKKE"
     gene            4099..4494
                     /locus_tag="KRH82_003266"
     CDS             4099..4494
                     /locus_tag="KRH82_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656531.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4537..6636
                     /locus_tag="KRH82_003267"
     CDS             4537..6636
                     /locus_tag="KRH82_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBG8656532.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6861..12071)
                     /locus_tag="KRH82_003268"
     CDS             complement(6861..12071)
                     /locus_tag="KRH82_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBG8656533.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKRLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDDSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKDGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVNLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12086..14581)
                     /locus_tag="KRH82_003269"
     CDS             complement(12086..14581)
                     /locus_tag="KRH82_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8656534.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLERTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGKNGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
BASE COUNT         4897 a         2696 c         1675 g         5703 t
ORIGIN      
        1 aattttcttt tttaataaat ctttttcttt taataaatct atttaatttt cttcttctat
       61 atcagagcca aagggaatcc atgcattacc aaactcttta tctttaaata aataagctaa
      121 tccagttatt tgcttcaatc taagaatttc atcaacttcc atacccaggt gctttgatat
      181 ccattcatca gattttccaa tttcacaaag ttcagttata attttactca ttaaatccac
      241 attatgagaa cctcttgcac gattgtgtcg aatagtactt gccattcttt catcaagaga
      301 tttatcaatt actgaaacag gaagaagtcc attttctcta tcatatatat cctcattttc
      361 aagcattact ctatatctat gaaaaccatc tacaataata tacttatcct tttcctcatt
      421 ataataacag acaattggca ttgtataccc atcttctttt atacttttat acaacaactg
      481 catttctggt ggggctactg catttggatt atagtcgtta gattctatct tttcgattgg
      541 cactgcgatg attccatata caggactttt atattccata gcatcttaac tcctatctaa
      601 tgaatttttt catatttctt cttaatatat tccgttctaa ttctctgttc ttttgtagga
      661 ccaaatccca taaatctaca catatggtca ttttttaaaa tacaataaca cattcttttc
      721 caacttggta tatctttggt aaatttaata tcatccgtat catcaggtat atcatccaaa
      781 aatatgactc tactcttttt atcttttgta tgatttgaaa ctccatttaa ttctatttta
      841 taaccttttc tcaacaattc acgtataact atttctgaca aaccaccacc tgtattctgc
      901 caaaactcaa tagatgttga aaatttttta atatagctat tccttatatt ttcaggtaag
      961 gtatcaagca aaaaatatgt gaaacttttc catgtgtgtc catatggcaa tttaacacta
     1021 cgatatccca tagcttttgt tttgccataa atagaagtaa aattaactcc ttgtactcta
     1081 gcaaccaatt tcacccatac atctgggtcc aatattctgt ataaatttaa actctctttt
     1141 gctgaatcat taaaaggtga tgccactctc atttttcttg gagctactcc agctttatag
     1201 aataagtcat aaattttatt atagtcatag tcaaatttat agtgtgctaa ccatatatct
     1261 tctatttccc aatcatatat aggagatgcc gtccagacat ttttaaattc cttagttatc
     1321 cagcactttc ctttatatcc atgctgttta ttcacaatag aacaataacg ttgtagagat
     1381 tctgctgctc gtgttcctaa taagcaaaca acttttgcac cttcatgtat atctctaatc
     1441 catctaccaa attgttttgc caaactttct tgtctcattt tatatttata ataagtaaaa
     1501 ggattatttt tttgatttat tatgtattct ttgactggca tttcccttac ccataactct
     1561 tctttctcat catcccatgg ataccaatac atttcataat ttcctacagc agttcttgta
     1621 gccattggta aacacaccca atatggttca atatcttcaa tattatcttc aaatactttt
     1681 tcaacatatt cagtagtcaa actatattga gcctcaaaat cttgatgaaa tactcctatt
     1741 ttggaactta tattattctt tctcttataa tccaaaacta aatttagcag taaaccacta
     1801 tcttttcctc cgctaaaaga tacatagata taatcaaatt cattaaaaag ataagaaagt
     1861 ctttcttgaa aagcttcaaa tacatcggat tctaaatatc tcttatccat ttgaattatc
     1921 ccctttcaat tagaagttta taaaacctta caatgcaata ttattatgct tttttagcag
     1981 taatcagcat aaattataca ttatttaaat acacaaatcc aactaactac atataattat
     2041 aatgtaatta tacttttgta ttataaacta tattttatca ttattttaca tttttttcca
     2101 atatatataa atatcatatt tttctattag ctaaaactaa ttactttata tttctacgta
     2161 ttagtataat aatacataaa aacttgaata atgcataaaa acttgacata ctgttgtcat
     2221 aattactttg ctataattaa aagtaaaaat ggaggtaaat tctaatgtat gaacgtatgc
     2281 ttgataaaag caataaaccc tgtttgtctc aaataataga atatataggt aaagatggat
     2341 atgcacgatt gtgtaagttg gaaacttact tgaaaactca atataattta tcaagagaac
     2401 ttcgatttcc ttttggaaac aattatggtt ggggttacaa atatagccat aaatcttttc
     2461 atttatttta tgcttttttt gaaaaaggtg catttactgt tctgattcag ataggtgaca
     2521 agcaagttcc agcagtagaa aaaacgttgg tagctttgac accaaaagct aaagagctct
     2581 gggtcactcg ttatccttgt ggcaataatg gaggctggat taagtatcgt attttagaag
     2641 atgcagactt acttgatatt attcaatata taagagcaaa aaaatctcca cctaaacaaa
     2701 attaactttt attttttgtg atttaaatat agtgtatata aattccattc ttttcatata
     2761 aaaaaaataa tataaaaaat atctattagt ataacttatt tagtatgtct tattctactt
     2821 tttacagata attaaaaagt tttatcataa ataaatcata actagacatc ctagtaaatc
     2881 aaaattaatt tattcttttt tattagaatt tttgataaca gtccctatac atatgccaat
     2941 tatcattcca aaaattagac cataacacat tgtgatacct acatttcctt tagaaatacc
     3001 tatagcacaa cctatagcca ttccaagtat catgcctata aacatacata taataactaa
     3061 attgttgttt ttattcatag ttttctccat tcaatatatt ttaaattgcc tagctcgcct
     3121 tcttagctta aaacaaagaa atataaatta actttctttc attctaatat ctgcttgtat
     3181 aaatgtcaaa caacacattt cttgtcataa cctcctcttt ttgaagtaag tacaatctcc
     3241 cagacgcaat aatatcaatt tcctaaaacc atttaagtaa cttttatatt tacataatat
     3301 ttacaatcat aaactatatt gttattcatt tatacatcat aaacactccc tcctaatcat
     3361 tattatactt aaaataatgt tcatttataa taatatatct aacgcacttt aattgaaaaa
     3421 actaaaactt tgcctttcat tcccatatat aaataagtat actttttgat gctctattac
     3481 aaatcaacca aattaattga tataaattat cattttctgt tgaaaatacc attcgcacat
     3541 gctatactta attgcataaa tggtaataaa tgtcatatga ttttacaaat ctattaataa
     3601 caattattac ttttactgta ttttaaattt tttggactaa atatcaagaa ctttctaaaa
     3661 tacaaagtac aaaaaattta tataagttat aaatttatat gaactagata agctcaaaca
     3721 atatgttatg tataaactgt gtagtattcg gttataaatt tatataaatt atataagcta
     3781 gataaagtat tacctcaact atataagcta gatatataaa ttgcttatat aagctagata
     3841 agaattattt caactatata aactacatat ataaattaca tacataagct agatatataa
     3901 actgcatata taagctatat aagaattatt tcaaccatat aaactacata tgtaaaattc
     3961 atgtaaattt actaatataa atcaaataaa attactaaac tctctaaact aattttgtaa
     4021 aacatactct atttttaaca tttgttacct tatacataag tacaaacaaa atctaactaa
     4081 atgaaaggat aatgtaaaat gaatatttta aaaatgaaaa aaacagggat atttttagga
     4141 ggagtacttt ttggtactgt aggtgttaag atactttcaa gtgattgtgt taaaaaaact
     4201 tgcactcgtg caacagcagg agcattgaaa gttaaagatt ctgttcttga aacaactacg
     4261 aaaattcaag aaaatgtaga agatatttta gctgaagcaa aagaaatcaa cgagcaagaa
     4321 gacttatcta catctaaggt aaacgttgta caagatactc ttaaatgcga acaagaagtt
     4381 cttaaaactg aaactataaa aactgtagaa gatactaatt ctaatagcat taaatgtgaa
     4441 gaaatcaaag ataacgtaat tgaagaaaaa aatagtactt gtacaacaga ataaatttaa
     4501 tgattattat gattaataat atcaggagga agtaaattga atttttatat aaaacacgaa
     4561 ataagaggtc gtatacgctt tgacttacaa cttggcaaat taaacaacaa gcagtccgat
     4621 actctcttat attatttaac ttctataaat ggtattacca aagcaaaagt ttacgataga
     4681 actggtgatg cagtcattta ttacactggt gaaagagaat acataataag agaaatcact
     4741 aaattcagtt ttaacaatag caaaatagaa aacctagttc ctgaacatac cagcagggaa
     4801 ttaaacaatt attatagaga caaattagca aataaactgc tagtcaaaag tatctccaaa
     4861 atattttttc caaagtcctt aagatttttt ttaattggac ttcattctat aaaatatttt
     4921 aaaaaaggtc tctcttccct gctaaataaa aaaatagaag tttctgtttt agatgccact
     4981 gctataggta tttctatttt tagaaaagat atcaatacgg ctggttcagt tatgtttctt
     5041 cttggtatcg gtgaactatt agaagaatgg actagaaaaa aatctataga cgacttggct
     5101 caaagtatgt cactaaacat tgaaaaagta tggttaagaa aaggtgacac tgaaatctta
     5161 attccaattt cagagataaa ggaaggagat ttagtaagtg taactatggg aaatatgatt
     5221 ccattggatg gagttatagt atcaggagaa acaatggtca atcaggcatc acttacaggt
     5281 gaatcccttg cagttaacaa aaaagaaggc tcttacatat atgctggaac tgtaatagag
     5341 caaggcaata ttgttatgtg cgtcaaggaa aaagctggta ctactagatt ccagaaaata
     5401 gtaactatga ttgaggaatc tgaaaaacta aaatcttctg tagagagtaa atttgaacat
     5461 ctagcagata cattagttcc atacagcttt ttaggaagta tattaaccta tgcaattact
     5521 agaaacccta taaaatcact ctctatatta atggtagatt tctcttgtgc attaaaactc
     5581 tctatcccta tttcagtact atcagccatg agagaatgta acaataacaa cattactgta
     5641 aaaggtggaa aatttcttga aggtgttgca tgtgcagata ctattgtatt tgataagaca
     5701 ggcacattaa caaaagctca accaactgtt tcagatataa ttacattcca aaattataat
     5761 aaggaggata tgttaagact tgcagcttgc ttagaagaac acttcccaca ctccatagca
     5821 aatgcagtag tttatgaagc tgaaaaacaa gggcttagtc acaaagaaat gcatacagaa
     5881 gtagaatata ttattgctca tggcatttca acaaaagttg atgataaaaa ggttgtaata
     5941 ggtagcaaac attttgtatt tgaagatgag aagtgtacta tcccagacgg tgaggaggat
     6001 aagtacaata atctatcaga tgagtattca cacctattta tggcaatatc aggtaaatta
     6061 tcagcagtta tttgcataaa tgacccttta cgaaaagaag caaaatatgt aatttcaaat
     6121 ttaagagaat gcggaataaa aaagattgtg atgatgactg gagatagcga aaaaacagct
     6181 aaatctatag caagtaaagt tggtgttgat gaatattatt cagaagtctt accagaagac
     6241 aaagccaatt ttgttaaaag tgaaaaactc aaaggtcgca aagtaattat gattggtgat
     6301 ggaatcaatg attctcctgc tatttcagaa tcagatgtcg gaattgcaat gagtgaaggt
     6361 gctgaaatag caagagagat ttcagatatt accatatcag cagataattt gaataattta
     6421 atcgttttaa agcagattag taataagctt atgaaaagag ttgatttaag ttctaagttt
     6481 attatcggct ttaatttagg tttgatttta cttggtgtag gtggatttgt tagaccaagt
     6541 acatctgcct ttttacacaa cgcatctact gtcggaataa gtttaaacag tatgacaaat
     6601 ttattggaaa acaccaatac ttataactac cattaatctc cattacataa aacatatgat
     6661 ataaaaaatt tataattcat cttttaaaaa gaatatgtct taaaattagc ttttttctaa
     6721 tcaaaattat ataaagcata ctttacaaat tttaaactca acttatttct attttttaca
     6781 aaaaaggaga tgattcaaat tttcattttg aaacatcccc ttttgtaaat ttctttaaaa
     6841 tttatatatt aattatattt tcaaccaata attgtatttt caaccaatct ttcttcatag
     6901 cattttaaat cattttgctt tagataatta aattcagact ctacataaat accacagcct
     6961 accaattcaa ttgtcaaatt aggtatattt tcctttagta tactagtctg ctcataaata
     7021 attctttcca ataaattaac ttgtaatata gaaaaatgct tcataatctc cccatcacta
     7081 tctatatctt tcttgatttc ataccaactc tttgacaaaa ttcccttcaa atcaatatac
     7141 cctagactcc tcaatatatc tatactatcg ctccatgcat acttactagg tttatcaaag
     7201 tatgattcta gtttcttctt ctgctcattt gtaagtgaat cataagaaag cttcctatta
     7261 aaatgtgcct tcaaagaaat cttagccata gaatatggac ttctaccaga gtttaatcct
     7321 gcatttttga acttttcaat tcctttatct tctactgaag accatattga gtttattgaa
     7381 tctgaatcat tgtatttaat atcaagacca tgtgtaatat ttatatagtt ttgtggaaat
     7441 acatattgat aatagacatc ttttttatca tcatatagag agaagtatcc actatcatat
     7501 aaatgaatat gcacctttac ttttaaacta tcctctaaaa tatttcgtct aaggttcggg
     7561 atatttgcat acatggttac atattttatg gcatcaaagt ttttatttaa tggaacttca
     7621 aaactaattt catctcctgt caaaagcttt ttcacttctt cttcattaca atcatataga
     7681 gaatatgtat tttcaaatcc cacacgtgat ttcccatcta aactgcctgt taatgctacc
     7741 ttcaaaatat ggttatctgt tttttgccat tggtaagcat cttggtcaag aaactctcta
     7801 atctgtctat tttgctcttt cgcctgattt ataacctcgt tttcatcttc tgtaatccct
     7861 acatggcatc tatttaagat atttactata ttgcttccaa atgggaatgt ccatagttga
     7921 aaagctgctg cctcaacctg acacaaatat ctaacctgat ttaattcaat ttgatggata
     7981 agttttttct gatattcatt catctgatta ccactatctg acatttgata aatcaattct
     8041 cccattgcaa gattatcttt tttcttatca atcttatcag taatgataat ttgagtttcc
     8101 atcatatcct gtactttttt aaatattata gaaatctcct ctgaattttc catttttaag
     8161 cttccaaact ttgtgcttaa ttcagttaaa acttccttca tctttaattt acttatctca
     8221 ttttcaaaaa tatcttgatt tttaactgta ctatcgaatt tttctacaaa tggtataaca
     8281 gattctttca aagttttatc tttaaattcc accatttgag tattcaattc atctaatttc
     8341 ttaatattat tttctttatc tttaattgcc tctttaacta cctctatttt actctcaaaa
     8401 ctagatttta cattaagaca attattaaca ccactaatcg cagtatttat aagagaacaa
     8461 gcagaacttc caatactcaa tgcattttta attttagatg tcttttgctg tctttcaata
     8521 gcttgtttac ttttctctag tgcagctaac ttatcttttt gctgtttatt attgtaattt
     8581 gcctccaaca tacctatttc ttttttctgg atttttgtgt aaatttcctt atactcgctt
     8641 tcacttaacc cctcttttgc tctttgaata tcgtcagctt tgtctgcata gttatcatca
     8701 tctatagact taactataat ctccttaatt tggtcaaatt tagttcttct ttcttcatca
     8761 acacctgcca aattataagt cattttatct aaagcatttt ttctatcttc acttagctgt
     8821 tctccaagta caaatctcat accatcagaa tccaatttaa aatctgaaaa atcaaccatc
     8881 ctgttagtcc atttgtattc ctcttcttta gctgaaagat tttccttcaa agattttgca
     8941 ctgtcaaatg cccctagaca agcttgacca acaccactaa atgcagtcag taaactcaat
     9001 gcgctttgta ttccagaaag aattaactgt gttttcattt gttcctcaag ttttgcctgt
     9061 ttctttttta gttcctctat gtcttcttgt tcatcttctt tcatctttat aatttcttga
     9121 atcaacaggt tcatttttgc attaacagaa agcattttat tctcaagttc attttttaaa
     9181 acctctattt gttgatttcc agattcaatt tgagttagga tactttcctt atatgtattg
     9241 aaatatcctt cttttaactc atctttcttt ccttgttcca attctcttaa ggtcttatcc
     9301 agataatctg tcaaagaacg aatatctgta acacgatttc ctccaatttc actttcttca
     9361 atcatctgca cataaaatgc tgtcttctgc tcaagtgcaa ataaaatcat actccattcg
     9421 ctaaaattct gattttttcc tacaaaagat tctattctat cagactgcat caatttattt
     9481 ataaggtatt catagatttc ctttgcctct ttataaaatt ctttctttgt attcatatca
     9541 tccagagaaa gtactgcttt atttttcttc tcaaaactat agtacttctg aagtatttct
     9601 ctatttaatt gcatctctat tttctcaact gcataaaaaa tttcataaat atgtgaaaat
     9661 tctaaaatat cagcttctaa aattcctact gcacacaaca gtctaagatt tctataacct
     9721 ttaattccag aaaaaccaaa tctctcgaaa aattcataga agaatgtatc tattgacaaa
     9781 gaatactcct gctttaacaa ttccttttct tttagtgcat ctccagagtg accgtctttt
     9841 ccctctgctc cggctgaacc tgaatcttca cgtttgctaa ttgtccagtc cttatgttct
     9901 tcataaagag tatttaattt ctctccatca tctgctgctt gcttctgatt taaagcatga
     9961 ttaaacacat atctatcaaa ataatagtag tttctatcac tatcatccat tggaggagag
    10021 gtacctatat atcttattgt ttcttcatat atacctctaa ttccaccaag acctcctgca
    10081 ccaccagctc ctccagagcc tccttttcct gctaaaccat gatttccatc ttttttactt
    10141 atagcacttt ttaataaagg agcttttcca aggagataaa cctgtccaga cttgcttcca
    10201 agacctgcat ttccaccatt acctcctgtg cctccagttc caccttgttt tcctttttct
    10261 gcttttacca catagtattt tgtaccttta acattagcaa attcttttga ctctttttta
    10321 gaacctattt tagcatttgc cccagcttct ccagttatcc ctgtatctcc tttttttcca
    10381 tcttgtccat ttccaccacg tccaccatct acgtaaagtt taagttctcc tcttttttct
    10441 atttctttaa aagataatat gatatcacct gaagtacctg cattatttcc atttcttcca
    10501 ttcattccgt cgtaaataga actttctcca accaattttt ctgcatcctt accagatacg
    10561 ttgattgaat aagtcccttc tggtatatgt aatttttctg taagtagtac aatattctta
    10621 cctgagaaga cttctttctc catattacag tcaattttca actcacaatc tccatacata
    10681 tatatagatg acaaaatatt aagttgataa ccagatatta ttttagtcaa atccgataaa
    10741 ttcactttag gtataggaat atatatagaa agtacatttt ctttctcata tgattttata
    10801 tatgtacaac tttgaatctt ctctatccta tactctgcat cttcaagcct tttggcttct
    10861 tcttccctat attcttcttc tgctatccaa tatttgatat ctttcaatgt atcttctaaa
    10921 gtatttttta gcaatgattt taacaactca cttagaccaa caatatgagt ctcactacag
    10981 taactattta actctaaaag aagacgtgtt tcttctaata tattcacttt ctgtacgcca
    11041 tcaccatatg aaagttcttg tacaaactcc ataagctctt tcatattatt agtcctacta
    11101 cataaatctg tatacatctt atctaattga atctttttat cttttagact atttatagaa
    11161 gatagaatgg aaatagaatc ttccatacct tttttaacac tttctatata aggaactaaa
    11221 agtttttcta ggtctttata ggttacatca acagcttttt gtatttctat tttacaagaa
    11281 gcagtaagca tcaatcccaa atctgttttt tcaaatgttt caggtagatt tttcatttca
    11341 ttcaacaact tttctggctg tttatctagt ggattacata atttaataga tacaccatct
    11401 gataatgcta catttaataa gtacactaat tccttacaac cgtcgtaatc tttctcttga
    11461 ctatctaggt cttcttttgc tttttccaat atatttctta ttttttcttc tgttacatta
    11521 ccaattagtg ttttaggtat tttattgata agaaagaaga aattttcttt atactttgca
    11581 taatcaccaa gcatatcttt caaatttttg cctgtttcta tcaataatgt atgtctagag
    11641 tccagtaggg attgatagtc taaaataact accatccctt ttacctttga agatgtggaa
    11701 atagtttccc ttacaagcat agcaccagca atcatatact ctgctccacg gttgtcaaaa
    11761 aaacctgggc aatcacataa tgaaaaatct ctatttgcaa tatctacaac ttctggacat
    11821 aaagtcttag aatatacacc atttccaatt tcgacagctg aatcttttgc agttatatat
    11881 atttgtccag tctcttcatc cgttttttct tccatcacac agccttttaa ataatttata
    11941 caagtactct ttccaacgcc tgaagcacct aggaataaca aaattgactt ttcttttaag
    12001 tcatattttc taagctcgtc tcttccttct tccaaaaggt ttacgatttc actataaagt
    12061 ttatttgcca tacatccatc cctttctata tttcggaaca atagccttga tatttttctt
    12121 taataagatt ctcttctacc tttgaaacag ctgttgataa cttagtattt ggagcattaa
    12181 atcctccatt gtctcctcta tctccatatt cagcgtattc tcttgctggt cctgttttac
    12241 cttcattcca gcttccacca ctaaattcta tatgatattt aattatacta tctaacttat
    12301 aatcccaact tgtaaaatat cctgtatagt atacagtctt atctatacca cttggagaaa
    12361 atgaaagtgt attatatccg tgatagccac cacttcctcc atatccacct aaacctggtc
    12421 taccatttgg acctgcttct ccatctttca ctgttatatc acaatgatta attattctat
    12481 ttttttgttc ctctgaatct gaaatgaagt aaatattacc tttcttacca gcatttccac
    12541 ctcttccagc atttccacca gctccacctt tttcaccttt tttgccactt gtaccttttt
    12601 caaaataccc tttaaacatc tgtccgtgga aataacttgt atatcctgca tcagctccat
    12661 tacttccaga agctcctgtt tcaccatttt tcccatctat tcctttagaa ccatttcctc
    12721 catttgcaat cagtgttaga cgataatttc taatttcttc tttaatatat aagtaaatat
    12781 tacctgcatc tctaccatct tcaccatttt tcccatacat agaattatct acaagttctc
    12841 cgctctttcc acttacatta atttttacat tactacctac atcaagattg ttagaagcaa
    12901 gaataatatt tttctctgat gcaaagttca ttccaaggtt atcatccata taaatagtat
    12961 ctttagcaaa gaacataaat gtagaaacat tgtcatctac ttttctattt ttgaaatatt
    13021 ccaatacact gctaattact aagtttggaa ttaatgctct tatttcaata cctttcttat
    13081 cattaatatt aattgttttt actataaatg gatttaaaat gtatttacca ataaattctc
    13141 taattatctc attaccttct tctccatatg cacttaatct tgttatactg tcttctaact
    13201 cttcattttg tgtaactgta acatttgtca aaattgaatt aaaatcactt acactatata
    13261 cataatcctt tttatttgca acttccatta atttttctct atttggtaat gtaaatacct
    13321 gtttttgcac ttcataagaa actaaaactt tttctaaatt ctttcttatt ataatgaagt
    13381 tttgttccat tatcttctta cttgcctttt ctataataaa ttccatatgt acagaaggta
    13441 ataaaatttc cccagttcca tgttctgtat atttacttaa agcatcaatt atatctaagt
    13501 ttccttttat cttattttgt aatttcatgc aactatcttg taagaataag ccactttgtt
    13561 tggctaatac gttgataaaa ctctctatag taagacttgt tgtactttcc aaccagtttt
    13621 taaatacttt tacaacctca tcatattttg ctatttcttg aatcattgtt atacttccaa
    13681 taatattgat aaaatcttct gtatacgcct taacataatc ttctaggcta gatacgatat
    13741 tgttttgaat ttcttttatc aacgtatcta aaactaatct tgcatctgca ctaattggat
    13801 attggaatgc tgatgtctta tctttaactt catctaattc tagtacttgc tttaataagc
    13861 cttccctctc atctgatgca agtggcttac aaagatgaat attttttcca ttatctttta
    13921 gcaattcttc aaataaccaa gctttttcct ctatattact gtctaaattt tcgcataatt
    13981 gttcatattt tctttttata acattatata tttgtttttc tgttctttct aagaaacttt
    14041 ttgaaatgaa aaaagttata ctacccttaa aattttcttt atgaagacac atatttaact
    14101 gttggaacag gtctagtact tttgtaagtc tagaatctaa tatatctgct tctggtatca
    14161 atacaattac tgcacatata gatgcagaat ttttaaatac ttcacctaat gaaactgctg
    14221 cactaatatc atgggctact cccctattgt cgctaaaacc tgcagtatca cataattttg
    14281 catccattcc ttctattggt tttctcatat ttacaatgtt cgggtataaa gtttgagaaa
    14341 cagctcctga accaatctct gccacagggt ctaagcaatc aatatatgat ataccagtat
    14401 cttcatcttc tacttccatc attacacatc ctgcaagata gttaattgca gtacttttgc
    14461 cacatcctgt cccaccaaga attagaatta aattttgatt ttcagcctta tttattgcta
    14521 cttttccttc atttaataag agtgttattt cttctaaaag ttgattgtta ttttctggca
    14581 tttattttcc cccttggtta tatattttat ttaaataaag tttaatccct taagtagatt
    14641 acaaagtttt tagactatat ttaaatttgt tttttatttt ttatttttaa taaatttgct
    14701 ttttcactaa atttgcattt tcactcaata attattcttc tttgtttatt aaaataactg
    14761 tgttgtataa tataatcttt accaacacag ttattctatt taatgcgctt attttattgt
    14821 attttatgta atacagttgt tttttatatt atacgtccat tattttccta tggttattac
    14881 atatagattt ttaattatat ttgtaccatt aatttaaaca ttcctatact actgcttaag
    14941 ttttacacct ataccagctt gaatatttta t
//
LOCUS       DAEOTL010000094        13787 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEOTL010000094 DAEOTL010000000
VERSION     DAEOTL010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13787
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.095"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(413..964)
                     /locus_tag="KRH82_003270"
                     /pseudo
     CDS             complement(413..964)
                     /locus_tag="KRH82_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
     gene            1172..1262
                     /locus_tag="KRH82_003271"
     tRNA            1172..1262
                     /locus_tag="KRH82_003271"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1206..1208,aa:Ser,seq:gct)
     gene            1350..2138
                     /locus_tag="KRH82_003272"
     CDS             1350..2138
                     /locus_tag="KRH82_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBG8656535.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            2159..2899
                     /locus_tag="KRH82_003273"
     CDS             2159..2899
                     /locus_tag="KRH82_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBG8656536.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            3075..3449
                     /locus_tag="KRH82_003274"
     CDS             3075..3449
                     /locus_tag="KRH82_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656537.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            3541..5001
                     /locus_tag="KRH82_003275"
     CDS             3541..5001
                     /locus_tag="KRH82_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBG8656538.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFENFKAELENAIKK"
     gene            5054..8083
                     /locus_tag="KRH82_003276"
     CDS             5054..8083
                     /locus_tag="KRH82_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8656539.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            8160..10226
                     /locus_tag="KRH82_003277"
     CDS             8160..10226
                     /locus_tag="KRH82_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBG8656540.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDENDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDIWKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    10609..10819
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11045..11860
                     /locus_tag="KRH82_003278"
     CDS             11045..11860
                     /locus_tag="KRH82_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBG8656541.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            11888..12565
                     /locus_tag="KRH82_003279"
     CDS             11888..12565
                     /locus_tag="KRH82_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBG8656542.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            12624..13346
                     /locus_tag="KRH82_003280"
     CDS             12624..13346
                     /locus_tag="KRH82_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBG8656543.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
BASE COUNT         5577 a         1369 c         2420 g         4421 t
ORIGIN      
        1 gaaaatatta aatgactgaa taaaaaacga ttgtgtcaaa aacaaaaaat aattaagtgt
       61 aagaatgatt gtatcaagaa tataaaatga ttcaacaaaa aacgattgtg tcaaaaataa
      121 aaaataatta agtgtaagaa tgattgtatc aagaatataa aatgactgaa taaaaaacga
      181 ttgcgtcaaa aataaaaaac aattaaatgt aagaataatt atgtcaaaaa tataaaataa
      241 attaaaagaa aaagattata ttgaaggaaa aagatttgaa ataggggtga actttacata
      301 ttatagttca cccttataca aaaatataaa atataattta ttataggaaa atttaaaaaa
      361 atcagtctat ttaatttata ctgatatatt gtaggatttt acaaacaaac tgttatataa
      421 ctttttttat ctccaatttt gattttaaga tatctaagaa tttataacaa tcttctggat
      481 atatttctcc catatttgct acttggaata tgttagcatc taggaatttg ccttttcctg
      541 gatagacaac atagccactt tccctttcta gccctaatat aaactcattt acattgattt
      601 ctttaggtag aaatacagat gttactgtat tagacatata cttatctgga agtaaaaatg
      661 ttagacccaa ttcttccata ccattcctta aaatagcaga acattctttg tatctttcta
      721 ttttactgtc atcttccaaa aactcagtta aagcttcatt aagggcaaat attaaagtaa
      781 cattaggtgt atttggtgtt tgagaagatg atttagcaac tttatagtgt ttataaagat
      841 taagatacac attcttacat tgattttctt taatattttg taaaatactc tctttagcac
      901 aaaggtatgc agaacctgga aatgctccaa gagctttacc accaacacct gttattatat
      961 ctattaagtc agagtttagg tatatttgtt aatgtatgta tatttatcaa ataatattat
     1021 aagtgttatg caagataatt ttaccatatt taaaacttac atttaagcaa aaaagtaaaa
     1081 atagatgttt aataattcaa aataactcaa attttataaa acaattgact aaaatatgat
     1141 tttattatat aatttactag tatagagata tggagaagta ctcaagtggc tcaagaggat
     1201 cccctgctaa gggattaggc tgggtaaccg gtgcgagggt tcgaatccct ccttctccgc
     1261 caattattaa aggctatttt tattaaagat agtcttttta taatgtcata aatgattaga
     1321 tatgtataac taaagaaagg agggaataga tgacaacttt aatttttttc atagtgggga
     1381 tagcatcttt ggtagttgct tttgttattg atgggggaca tgttggagca ttatttgtat
     1441 tttcatcagc acttgttgtg tttggtggaa ctataggagc tgttggagct tcgactccat
     1501 tccctgtgtt taaaaagtct ataaagataa tgttattagc ttttaaaaat aaaaagccta
     1561 ataacataga aaatataatc tatttcaaag aaattgcaac aaaggctagg aaagaggggc
     1621 ttcttagtat tgacaaagaa ataagtgaga atgatgaatt agaccctttt attagaaaag
     1681 ggcttgaact tatggtagat ggagtggatg cagttactat aagaaatata ttggaatcac
     1741 agatacagat aacatcaaaa cgacataaag aaggaatagc aatttttgat tcagcaggtg
     1801 gatatgcacc tacactgggg ataataggta cagttatggg attagtacat attttaggta
     1861 atctttcaag taatccagat gcattaggac ctcaaatttc tgttgcattt ttggctactt
     1921 tgtatggtgt tggttctgcc aatttaatat ggttaccaat agcatcaaaa cttaaggcta
     1981 taaatcaaca agaagtaagt gaaagacttt tggtgataga agcaatatta tccatacttg
     2041 agggtgataa ttctaattta atgacagaaa aattaaaaat atttttaaat tcaaaagaac
     2101 taattgaact tgaagaaatt ggtggtagag ctgaataata taaaaggatg gaatgtttat
     2161 gttgtatgat gaagatgaaa aagaagaaaa caatgagcga tggcttttaa cttattcaga
     2221 cctcataaca ttacttatga ttttctttgt aataatgtat tctatgagta atgttgatgc
     2281 ggagaaatat aaacaattat ctcaatctct aaattctgct tttggtggtt cttctggagt
     2341 tattgaaggt ggtaatagca agatagaacc agtagttgaa ccaggaagta atgatttaga
     2401 tactttacaa aatgctaagt ttaaaaaaat tggtgaagaa attcagaagt atttaaacga
     2461 aaatggtatg gctaattcag tatcattaag agttcaagat agaggattag taataagcct
     2521 taaagataca atactatttg atacagggaa agctattgtg aaggataatt ctagagataa
     2581 gattattcaa ataggtaaga tgttaaatga aatgaatagt tacatgagag tagaaggcca
     2641 tacagacaat atgtctataa aaaattcaga gtttaagtca aattgggatt tatcagttat
     2701 gagagcaacc aatgttgttc aacttcttat tgacaatgca ggtatagcac cagataaatt
     2761 atctgctgta ggatatggtg agtttagacc aatagcagaa aattcatctg aagaaggtag
     2821 gtcaaaaaat agaagagttg atatagtttt agttgatagt aaatatgata atgtagaaaa
     2881 tgtttcaaag gataaatagt taaattagct gtctcaatac agaattaatt ctaaaggaga
     2941 tggctttttt atgcgaaaat caaaaataga tacatagtaa gttacctttt tgtaggaata
     3001 tatggtatct taaatatata atatttaaat aatgtataag ctcaattaaa aaatttatag
     3061 aggatggaaa ataaatggga aataaaaata aaaatactaa atataaagat aaaacaagag
     3121 aaaggtataa taaaaaagtt gagaatttaa ataaagaaaa attaaataaa attaataagc
     3181 aatctaagaa ggtagataag attgatgata ttattaataa atctagtatt gtattatgtg
     3241 tacttctagt agtgttttca ttgctttact tatttaaact ggttcaactt aatataataa
     3301 tgatactttt agtaattaca gtagctattc aacaaggatt ggtgtcattt ggtgcattta
     3361 gaaataaaaa ttatgtaaaa gctttatttt ctatatttgt aatagtatgt ttcttaattg
     3421 cttttaaata tgttgtaaat cctgtttaaa tatatcaata aacgttctat aattaatata
     3481 aatagtgaag ttacagtttt aatgctatta taaattttat aatttgaagg agtagatttt
     3541 atgaataggt gtaagtttgc aaaattaatt atcacatcaa tgattgtttt attacttaca
     3601 ggatgtagtt taaagaagga agataattat aagttagacc cagaaaatcc gacatcaata
     3661 caaatttggc attattataa tggacagcag aaaatggctt ttgataagct tgttaaggaa
     3721 tttaatgaca ctgtaggtgc tgaaaaagga attattgttg aagcattcag tcaaggtaat
     3781 gtagttgatt tatcagagaa agttttagat tctgcaaata aaaaagttgg ttctgaagat
     3841 gtaccaaata tatttgcagc atactcagat actgcatatg aaatggataa attagggtta
     3901 ctagtagata tggataagta cataagtaaa gaagaattaa atgaatacat agacgaatat
     3961 gtagaagaag gcagaataaa ttctaaggat gagtttaaac ttttcccaat tgcaaaatca
     4021 actgaaattt tgatgttaaa taaaactgat tgggataaat ttgcaaaagc tacaaattca
     4081 aatataaatg atataaaaac aattgaagga ttagtagaga catcaaaaaa atattatgaa
     4141 tggacagata gtttaacgaa agagcctaat gatggtaaag cattttttgg aagagatgct
     4201 ttagcaaatt atattattat aggaagtaaa caactaggag tagaaatttt ttctgttaaa
     4261 gatggtaaag ttacactaaa tattgatgaa aaagttatga aaaaactatg ggataatttc
     4321 tatgtaccat atataaatgg atattttgct tcttatggta agtttcgttc tgatgatgca
     4381 aaaacaggtg atatattagc tcttgtaggt tctagttcag gagcagcata ctttccagat
     4441 agagtaatgc taaatgataa tgagagttat aatattgaaa catctgtttt tcaagcacca
     4501 cgttttaaag gagaaggaaa atatgctgta caacaaggtg caggaatggc tgtaacaaaa
     4561 tctactaaag aagaagaata tgcatcagta gaatttttaa aatggtttac agataaagaa
     4621 cctaatataa aattctctat tgcttctgga tacttaccag taaagaaaaa aacgaatgat
     4681 ttggatgtta taaaagaagt tatgaagaaa gataatttga gtttatctga taaagttgaa
     4741 ggttcaatag cctcatctat tgaacagatt aacagttgta atttatatac taataaagca
     4801 tttgatggtg gaactaaagc tagacaaata cttgaatatt caatgcttga taaagctaaa
     4861 gaagattcaa ataaaataaa tgaattagta aaaagtggaa cttctaagaa ggatgcagta
     4921 gcacaattta ataatgataa aaattttaaa acttggtttg aaaattttaa ggctgagctt
     4981 gaaaatgcta taaaaaaata gatgaattgg cagttagtgt gttgacgagc acaaaggtat
     5041 aggtggaatg ggtatggaaa acaatctaag aaaaaacaat tcaataatga aaaagatgat
     5101 atttccccta attattgtta tgctaattca aacaagttta ttttgtgcca caattttatg
     5161 gggaggaact attaagaaat taaatgataa ttcgtttgac atcttaaatg aaagagtaat
     5221 taatcgtaaa aattatatac aaaatgaaat gttacaaaga tggtcaaata caagtgaaac
     5281 ggaagctaca attaattcct ctgtaaaaaa agtattaaat gaaaaaaatg ccttaattga
     5341 ggatgtaggc aacaatgaag aaattaacaa agatattata aaaagcatat caaatgattt
     5401 aatatatctt ttgagaaaaa attctgttac aggagctttt ataatcctaa gtgacaaaaa
     5461 tattaacgat aagtcaatag atagtaaagg tgaaataagt aggacaggat tgtatataag
     5521 ggatttagac cctaagttta atccaaatga taattctgat ttgttaattg agagaggttc
     5581 atcagatata gcaagaagtt ttggaatatc tatggacagt tattgggaac ctaagttttc
     5641 atttaaaagt gaaaatgagc aagatggaga tgattttttt tataaaccat ttagagctgc
     5701 aattgataat ccaaatgtat caagttctaa tttaggatac tggggaagta agtttttatt
     5761 gacaaatgca ggtgataggc ttatgacata tacagttccc cttatttatg aagatggaac
     5821 tgtatatgga gtacttggaa tagatttaag tgtaaattat ttaagagaat tacttccata
     5881 ctcagagata aatgggaata aaaagggtaa ttatatttta ggtgtagata gaaataatga
     5941 tatggccttt gaaaatgtaa tttcaaatgg atactcatta aaagaaaaat tttgggatgg
     6001 tttacattct aatttagagc agaaggaatc gtataaaaat atatataaga ttaaaaataa
     6061 agataatgaa tgtggtaatg gcaacattta tgctagtgta caatacttag atttatataa
     6121 ctccaatact ccatttgaaa atgaacgttg ggctcttttg ggtattattg aagaaaaaag
     6181 tcttttgtca ttttcaaaaa gggtagagaa attagttata atatctatag caatttcttt
     6241 attaataggt ctaataggta tttatattgc atcaagatta tttacaaaac caattgttct
     6301 tttagccaac aaagttagaa acagtaatcc atcaaaacca gtaaatcttg ataagataaa
     6361 tatatctgaa atagatgaat tatcttcagc tatagagttg ctcagtgcaa atgttgcaga
     6421 ttcttcgtca aaattatcac agattattga aatggtagat atgccaattg gagcttttga
     6481 gttatacaaa aacgcagaga atgttttttg tacaaaagaa ttttttagcg tgtttactac
     6541 tgaaatcaaa tttgaagaat atggatatat ggaaaaaaat aagttcctga aaaaattaag
     6601 gggactagat aaatatttgc aagaaagtta tgaaacagaa aatacatata tatataagtt
     6661 tgaatctaaa gataaaaaac ttaagtggat aagaatgaat atctttgaag atgagctaaa
     6721 ggttcttggt gttgttgttg atgtaacaaa agaatttatt gagaaaagga agatagaata
     6781 tgaaagagat tttgatattt taacgaatct tttaaatagg agagcttttc attcacagat
     6841 acaagaaaaa tttaagaata aagatgaact taagatagca gcatttatta tgtgggattt
     6901 agataatcta aaatatatta atgatacata tggacatgat gctggtgatg aatatattag
     6961 gtgtgctgca gacatactta agaagtttat atcatggaat ggtatagtat ctagactttc
     7021 aggtgatgag ttttatgtat ttatatatgg atatgaaagt aaagatagta taagagatat
     7081 tattaattct gttaagaaac agatgaataa taccttatta aaacttcatg atggaacaga
     7141 atttaaaata agggcatcag caggaatttc ctggtaccct gatgattcaa ccaactatga
     7201 tgaattaatg agatacgcag attttgctat gtatcaaatt aaaaatacaa tcaagggtga
     7261 agttagtgaa tttgatatta atatatataa taaggattca ttcttattga gtaatagaga
     7321 agaattaaac aagttaattg atggtcaatt agttgagtat gcatttcagc ctattgtaga
     7381 ttgtaaaggt aaagtttttg catatgaagc acttatgaga cctaaaataa aaacttttag
     7441 ttcaccaata gatgtcatta gattagctcg ttcacagtct aaattatatc aaattgagcg
     7501 tattacatgg tttaaagcac ttaaatcatt taaaaaatac aaagaaaaat ttggcgattg
     7561 caaactgttc ttaaattcta ttcctaataa taatttgtca aaagtagatt ttgaggaaat
     7621 tgaagattta tatggtgaat atttaaatag agtagtacta gaaataacag agaatgataa
     7681 gattaatgaa gattttattg agaaaaagaa agcatatata gaccattgga atatagaaat
     7741 tgctttagat gactttggga caggttacaa cggagatgct gtactattat atataatgcc
     7801 agactatgta aagattgata tgtctattgt aagaggtatt gataaagatg aaaacagaca
     7861 gaaaatatta aaaaatctta tctcatattc taacgaaaga aatattaaag tgatagcaga
     7921 aggtgtagaa acaaaaggtg aaatggaaac actaattaat cttggagtag attatatgca
     7981 aggctactat attagtaaac catcatttat acctgaagat ataagcgaca aaattaaaaa
     8041 agaactcaag atatgtcatg aaaataggaa tgatgtggtt taatagagga aaaattaaat
     8101 ttatttttat gaacttttag tttataatta aaaagaaaat aatataatta taaatcaagg
     8161 tggtggagct aataatcaca acaaatatag atataagaaa gttaaatgaa aatcaattag
     8221 aagcagttga gcatatagat gggccttgca tgatacttgc agggcctggt tcaggtaaga
     8281 ccagagtaat tacatataga atagccaata tggttgtaaa caaaaacata gcaccaacaa
     8341 gaatcttggc aataagtttt accaaggcat cttcaataga aatgaaaaat agagctttga
     8401 atttaagtga tgatataaga cttaataagg taacctatgg tacttttcac tctgtatttt
     8461 ttaaaattct aagatacttt gaaagataca acttagacag tatatttgat gaaaagtcaa
     8521 agcgaatgac aatcaaggca atcctaaaaa gtttaaatat agagaatgct gatgatgatg
     8581 agaatatagg acaagttata aatgaaattt cctatgtaaa aaatgaactt atggataaaa
     8641 atgaatttaa ttcagaagta ttaacaaaag atgagttttt aaaagtatac aacttatacg
     8701 aagaacaaaa atctaaagtt aataaaatag attttgatga tatgcttata agaacttatt
     8761 atttactttt gaacaataag tctgcactag aaatggttag aaatgtgtat aaatatatat
     8821 tgatagatga atttcaagat ataaataaag tacagtttga agttttaaag ttaatttgta
     8881 gcccattaaa caatatattt gcagttggag atgaagacca aagtatatat ggatttagag
     8941 gtgctagacc agattttttg cttgaatttg aacaatactt taataatact aaaaaaataa
     9001 tattagatat aaattacagg tctaaaagtg agatagtgca tactgcaaat agacttatcg
     9061 acaaaaataa aaatagatat gaaaaaatca ttaagtgtag tcagggggat ggaggaagtg
     9121 ttacctatat ttctccgcat gattcagagg aagaagcctt atatattgcc agggaaataa
     9181 ttgacgaaat acaaaaagat tatgtagagt attcagattt tgcagtaatt tatagaacta
     9241 atatacagtc aagagcatta gtagatgtat ttatggatat gaggattcca tttgtagtaa
     9301 aagactcagt aattacaata tatgaccatt gggcaagtca agacatacta gcctatttaa
     9361 gaataggtat taatccaaaa tcaaataaag attggttgag aattataaac aagcctttta
     9421 gatatatatc caaagacagt ataaatatgg ttaaggatga aaatgacttt ataacagcat
     9481 taataaataa gtgtaatctt catcctaaac aagttaaaac aataaatgat ttggaaatag
     9541 atttaagtta tttaaatact ttaaatccta aaaatgcaat atcttatatt agaactagtc
     9601 ttgattatga tagatatgtt ttagattatt gtagcaacag aaagataaag actaatggac
     9661 ttgtagagat attaaatgaa cttgagagtt cagcaactaa ttttaatact gttacagagt
     9721 ttttagagca tattgataga gtaaagactg agttaacgga aaataacaag aataagcaga
     9781 ctgagggtgt catatttaca actatgcata gtgcaaaagg attagaattt agaaatgttt
     9841 atattatagg tgtaaatgaa ggaacaatac ctcatgaaaa atcatatgat atttggaagg
     9901 aagagaaaaa agaagaacaa ttagaagaag aaagaagact tatgtatgtt gctattacaa
     9961 gagctgaaga aaagttatgt ataagctcta ctttaaataa gtatggtaag aaagttgata
    10021 aatcattatt tattaatgat ataaaatctc caacgaaaaa agaaattgac agtattggtg
    10081 taggagataa ggtataccat aaaaaatttc atgaaggaga aataattaaa aaagatggaa
    10141 ttatgtttac aataaagttt aaagatagag agcgaatcct ggatttgaaa acttgtttat
    10201 tgaagaatat aatttatact atttaattta gaatctaaat ttagatagaa atataatgta
    10261 ttatttatta tgtgcaagac aaatagatat gtgtaaagtg tattatttaa cttattagaa
    10321 aaagaaataa gggtttaata tattatttat agttgtttag aaaaagcaac aatgtggaaa
    10381 atattattta gtattattaa agaaaagcaa caatgtgaaa gatattattt agtattattt
    10441 aagaaatagc taaaaatatg aaatatacta tttataatta cacaaataat atcaataaat
    10501 ataaacagta gtatttagat aatttacaag taaaaattat taaaaaaata aaaaacttat
    10561 tgacaaaaat attataagga agtacaattg tattaacaat ttaaggaaac aaatccaatg
    10621 atagagaaag tagcatatat ggatttacag cgagttaggg gttggtgtaa gcctagcaat
    10681 gaagtctatg tgaagagagc tctggaggag attatcagaa actttagtat gataattggt
    10741 ttacccgcct taagggattg agaggataag tacttactta tcaaaaagag tggtaacgcg
    10801 gatataattc gtctcttagc tgtaaagcta agggactttt ttgattttaa aataaaaata
    10861 tccatacagc ttaaaagcta acagtcacaa attttgaaag taatataagt atttatcaat
    10921 aagagtggta acgcggtaaa gtcgtctctt agtcattaaa gactgagaga ctttttttgt
    10981 aactcgaaac atttaagtat taaaatctga gggaaattat aattaaaaga gaggggtagt
    11041 taaaatgaaa gtatttaaaa aattattaag tttaggatta gtattaggat tgacattatc
    11101 gctagtagga tgtagtggtg gaggagaaaa aacaaagtta gaacaaataa aagacaatgg
    11161 aaaattagtt gttggtacta gtgcagaatt tcctccattt gaatttcata aggtagtaga
    11221 tggaaaagat tcaataaaag gattcgatat aatgttggct gaagaatttg caaaagagct
    11281 tggtgtaaag gttgaaatta aggatatgtc atttgatgga ttaataggtg ctttaaatgc
    11341 agaccaagtt gatattgttc ttgcaggtat gtctccaaca ccagagagag aaaagagtgt
    11401 tgatttttca gaattatatt atttaagtag aaatgcagtt atagttaaag atgcagatat
    11461 agacaaagta aaaactgaag atgatttaaa gaaacttaga gttggagttc aagcaggaag
    11521 tatccaagaa gaatatgtag ttaacacttt aaaaatgaca actacaaaat ctttgaaagc
    11581 aatacctgat ttaattacag aattaaaaaa tggaaacata gatgcagttg ttactaatga
    11641 agcagtttct ttaataaatg ttaaaaaata tgatggaata aaaatggcaa atactgaagt
    11701 tgggaaagat gtaacagaag gtatggcagc agcaatcaaa aaatctgaca ataacaaaga
    11761 ttttatagaa ttattaaaca aaaagataaa agaattacaa gatggcaaga agatagaaga
    11821 atttttaaat gaagcatcta ctgaagctgc ttcaaattag taagaaagtt atgtgggaga
    11881 tgaaattatg agtttagatt ttagtttttt aagtagattt gggacttctt ttttggaagg
    11941 aacaggtgtg acagtatcaa tttctcttgt ggcattatgc tttggattta taataggtat
    12001 aattatctgt atggcaaaaa tatcaaagag caaagtatta agagcaatat catcaatcta
    12061 tattgaggtt ttaagaggga caccattatt agtacagata tatatagtat ggtttggttt
    12121 acctcaatta ggaataagat tccctatgtt gtttggtata ccaagtgaat ttatagctag
    12181 tgcatttgca ttatcagtaa actctggtgc atacgtggca gagatactta gatcaggtat
    12241 acaatcagtt gataatggac aaatggaagc aagtagatca ttaggattaa attattggtc
    12301 aactatgaga tatataataa tacctcaagc tataaaaaat atattacctt cattagcaaa
    12361 tgagtttatt acacttgtaa aagaatcttc aataatatct gtaataggag ttgttgagat
    12421 aatgcgtact gctgatatag taaaaaatgc agcatttaga gcattagagc cattaatagt
    12481 agcagcagca atttactttg ttataacatt tactctatca agattagttg gattattaga
    12541 aaagaaacta tctgtgtcta actagatgag agcatgttta gcatttaggg aaaacataga
    12601 atagtaaaaa ggaaagtgat aatatgatta caataaaaaa tttaagtaaa tcttttggag
    12661 atttaaatgt attaaaaaat atagacttag aaatcgctaa aggcgaaata atggttatag
    12721 taggtccaag tggttctggt aaaagtacac ttcttagatg tatgaattta ctagaaatac
    12781 ctacaggtgg agaaataata tttgaaggaa aaaatttggt cgataaaaaa actaatattg
    12841 atgaggttag acaaaatata ggtatggtgt ttcagaactt taatttattc ccacataaga
    12901 ctattttaga taatataaca ttagcaccaa ttaaattaaa aaagatgact aaggaagaag
    12961 cagaaaaaaa agcagaaatt ttgttgagta gagttggtct tttagataaa aaagattcat
    13021 atccatcaca attatctgga ggacaaaagc aaagaatagc aatagctaga gcacttgcta
    13081 tggaaccaga tatgatgttg tttgatgagc caacatctgc tcttgaccca gaaatggtaa
    13141 acgaagtttt ggatgttata aaagaacttg ctaaagaagg tatgacaatg gcaattgtaa
    13201 ctcatgagat gggatttgct aaggaagttg cagatagagt tatttttata gatggaggaa
    13261 gtatacttga agataatact ccagaagaag ttttcggaaa tccaaaacat gaaagaacaa
    13321 aagcattttt agcaaaagtg ctataatata taaaaaggat gttattgata ttagaaattc
    13381 aatacatcct tttttagtga tggttaatat taattttaaa attaaagtta tattaatatt
    13441 aactttattt ttacgatttt ttgcagaaaa aaaaagagct cggggtaagc tctttttttc
    13501 caccgaatta atttccgtta ctaatccgat ttttaataaa tataaaatat atccttatga
    13561 aagggtattg ggaatagata tattaactaa ctagggttac cagggggata accttaattt
    13621 attataacaa aatgcgacac aaaaatcaat attttttttg aaataaatta taaaagttat
    13681 ttttataaca agtaagctta taaatttaac ttttatagta aaaataagta tatgtataat
    13741 ataatatatt tattttatat aatatattat tttatcatat attgtat
//
LOCUS       DAEOTL010000095        13755 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEOTL010000095 DAEOTL010000000
VERSION     DAEOTL010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13755
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.096"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(611..1354)
                     /locus_tag="KRH82_003281"
     CDS             complement(611..1354)
                     /locus_tag="KRH82_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBG8656544.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHKWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
     gene            1520..4087
                     /locus_tag="KRH82_003282"
     CDS             1520..4087
                     /locus_tag="KRH82_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656545.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            4317..4721
                     /locus_tag="KRH82_003283"
     CDS             4317..4721
                     /locus_tag="KRH82_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8656546.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            4745..5242
                     /locus_tag="KRH82_003284"
     CDS             4745..5242
                     /locus_tag="KRH82_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656547.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            5245..5646
                     /locus_tag="KRH82_003285"
     CDS             5245..5646
                     /locus_tag="KRH82_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBG8656548.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            5664..6152
                     /locus_tag="KRH82_003286"
     CDS             5664..6152
                     /locus_tag="KRH82_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656549.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            6179..6934
                     /locus_tag="KRH82_003287"
     CDS             6179..6934
                     /locus_tag="KRH82_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8656550.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            6934..7797
                     /locus_tag="KRH82_003288"
     CDS             6934..7797
                     /locus_tag="KRH82_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBG8656551.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            7844..8323
                     /locus_tag="KRH82_003289"
     CDS             7844..8323
                     /locus_tag="KRH82_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBG8656552.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            8388..9695
                     /locus_tag="KRH82_003290"
     CDS             8388..9695
                     /locus_tag="KRH82_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656553.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            10005..10145
                     /locus_tag="KRH82_003291"
     CDS             10005..10145
                     /locus_tag="KRH82_003291"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBG8656554.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            10655..11749
                     /locus_tag="KRH82_003292"
     CDS             10655..11749
                     /locus_tag="KRH82_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656555.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            11754..11954
                     /locus_tag="KRH82_003293"
     CDS             11754..11954
                     /locus_tag="KRH82_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBG8656556.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            11954..12871
                     /locus_tag="KRH82_003294"
     CDS             11954..12871
                     /locus_tag="KRH82_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656557.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            12868..13626
                     /locus_tag="KRH82_003295"
     CDS             12868..13626
                     /locus_tag="KRH82_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656558.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
BASE COUNT         5292 a         1425 c         2501 g         4537 t
ORIGIN      
        1 taaaatatat ttttatatgt tttaagtttt ataataagta atattgtatg ataaattaaa
       61 tttaaatatt tagagataag ctattataga atttgcttag tttaagttaa attttaaaat
      121 attcaaaaag gggctagagt ctggaaattt ttatttaaag aatacacata aaaatttcta
      181 gactctcatc atttaaaaga agtattctaa atttattatt tataattaaa tattatctga
      241 aaaaatggta tttttatacc tttgtttgtt atgcataatt ttacttagaa cataagcttt
      301 atataaaata attaaaaata tacctaatta aaataagtaa aaaaagagct atcatagaac
      361 aaatttaatt tgctcatgtg acagctcctt tttagatgat gcttttttag atttatacta
      421 taaggtatat aaaactaagt ttattaaaaa tgttataatt tctattgcta tcatagacca
      481 tatcaatcca tcaagttcat aaaagtaatt aagctttatt aaatagcttc tttattataa
      541 tttctttatt tcatataata taaatagtat taaaattttt atgggagtta aagtaagcat
      601 gtattattac ttagatattt gtataatcaa catctagtaa tttacctttt tggtgaaaat
      661 gattaataag ttttttagga taattcatta ttaattcatc tggaaaatta atttccttta
      721 agatattttc agaatactca tagttaccta tgtcaaaaca aatgtgagca tctgaagtca
      781 gtatgatttt agcaccatat tttttgcaaa gtgtagcaat atacttacag ttatccgagc
      841 taccatttct tgacacgcct ttaatagaac aattatttat ttctattaag atattctttt
      901 ctatagctaa tttaatgatt aattcatagt cgattgggta gtttgggttt ccaaggtgtc
      961 ctaatatttc aatattatca tgcttattta ttgcatttat taaagcttta gtattattct
     1021 ctaatgtatt tggagaaaac acagcttcgt gaaatgacaa gataagataa tctaaccgag
     1081 gaattacaaa aggctctagg tctatgtttc ctttaatatc tagtatattt gcttcacagc
     1141 ctcttaaaat tataatgtta tttatgattc ttgggatatt ttgaatgttg tgaaagtacc
     1201 atttgtgggg agaaccaggc atcttaggac catgttcaga tgtacctagt atcttaattc
     1261 cattttcttt acaataatta atattttcta gtaaagtgct atagccatga ccactgacta
     1321 tagagtgtgt gtgtaaatct gataaaaaat tcatataaat tcctcctcta taaaagatga
     1381 gggtaacgta atttatatta taaaacgaat aggaaagaaa atcaatagtt acataattag
     1441 acaaaaatat taaaatattg tagaattaag cttaataata aatgtttaac agtattactg
     1501 cttatagggg aggttaacta tgacacaaaa gaagctatca aggaaagaaa aagttttaat
     1561 ttgcttgaaa aggttaacag aagaacactt gaactttaat aatggcatta gatttggatt
     1621 tgatgcagaa tatatagcta ctgaagtagg tataaataga agtaatgcta gtaaggaatt
     1681 aaatcaatta ataaaagaaa gtattattat aaagataaag ggtaagcctg ttcagtactt
     1741 atataaagaa agtattgaga gtattttagg aaagaaacta aataaaggga tatttgataa
     1801 tattaactct ataaacgaat atagtgaaaa tgattctatc aaagatgagt atattttaga
     1861 gagtataaaa aaagagaaca atatttttaa tttagtagga tgtgatggaa gtttaaggtc
     1921 ccaaatagaa caggctaaag cagcagtaat atatccacct aaggggttga gtacattaat
     1981 aataggacct acaggagttg gtaaatctat atttgcagaa tatatgtata agtatagttt
     2041 aactataaaa gaagatagtg ataatgcacc atttatcata tttaactgtg ctgattattc
     2101 tgataatcag caattattat tagcgcagct ttttggatat gtaaaaggag catttactgg
     2161 agctgataaa gataagtatg gtattgtaca tgaagctaat aatggagtat tgtttttaga
     2221 tgaagttcat agattatctg cagagggaca agaaatgcta tttctgctta tggataaagg
     2281 gatatataga aggttaggag aggctaataa ggtacacgag tgtagagtta tgataattgc
     2341 agccactaca gaagacccag aaacagcaat gttggaaacg tttttaagaa gaatacctgt
     2401 aactataaag attccgtctt tagaggaaag aggctttcaa gagagaatga agcttatatg
     2461 ttattttttt aaagaagaga gtgttaggat tggtgttaag ttaaaggttt caaaagaagt
     2521 tattaaggca tttattttat ataagtgtaa gggaaatata ggccaattaa aaagcgatat
     2581 acaattaatt tgtgcaagag cttttttaga ttatatgacc tataaaaggg aatgtgtata
     2641 tgtaaggctc tctcttctac caaataatat tagagaatca ttatatggaa ataatagaaa
     2701 agaggagttt gtacaaaatt tcagttttat tggaaaagat gatattattt ttttaccaga
     2761 agaaaaggat tttgaaagtg aaaatttatt aatagaaaat aaaaaatatg atttagattt
     2821 ttatggaatg ataaaagaaa cttggaataa acttcaacaa gaaggtatta aagagtcaca
     2881 aattagaagt gttatagatg gagacataca gaagtattcc tataatttaa tgaatacttt
     2941 tatatataat agtagtaatc aaacagctta taacaacatt gttaatgatt caattgcaac
     3001 tactgtaaaa tatattttac aaaagcatga taaatggagc aaaagagaag gattagataa
     3061 attaataaaa gctatagctt tacatattca gaatttaatt gaaagaataa agattggaaa
     3121 tatagtaaag catcctaata aagatgaaat tatgaaggaa agagcatatg aatataacat
     3181 agcaaaagaa atattatcta acatgtcatt aatgtatgga gtagagtttc cagaagatga
     3241 agcaattttt ttagcaacat ttctttattt atcgtatgtg ggattaaatg aggagagtat
     3301 agcaatatta gtcataatgc atggtgaatc tacagcatct agcatggtga atgtagccaa
     3361 tactttactg gattgtaacc atgcagtggc aattaatatg ggattagaag atagagttca
     3421 ggatatttta gtacaagctg tagaaatagc caataaaatt gataaaggaa aaggaatttt
     3481 aattttaact gatatggggt ctattttaac atttgctaaa gttattcgtg atgctacagg
     3541 aaaagaagta aaagcaatag atatggtaag tacacctatt gtaatagaag caactagaaa
     3601 ggctctaact ccagaaatga cattagagaa attatatttt aatattatag aatctataaa
     3661 gaaacattat ggagatatgg aagttacata tgctgaaaaa gataatggtg gtagatattt
     3721 tgatagatta ctaattgata atattagtaa aactttgact tttttaaatg gggaaaaggc
     3781 ttattttata ttaaaagaag taattaatag aattagtgaa cactattctt tagtaattca
     3841 agatgaactt ttagtaaagt ttatatttca ttgttcatgt atgattgaaa gagtaataat
     3901 aaaagagtct ttagtttata aatcatatga agaaagaatt agtagaaata aagaattata
     3961 tttagttata aaagaaagtt ttaagctagt agaagagaca ttcgatataa ttatttcaga
     4021 tatggaatat gcaaatatat tagatatatt tgaatcacaa tatgatacag ataaattcaa
     4081 aagttgatac aaaatttaaa aatagccaaa aggctatctt ttttttactt tttttgatac
     4141 agatttgata caggttgaaa aaatcttttg atacatatcg aaataataag tttttaaaaa
     4201 aaattgagta aaaagttttg attaaatcct gtaaaatagc catttgttat tgatacacat
     4261 aagttggcac ggcaattgct tatataaaaa gtgacaagaa aagtgaggtg aaattggtga
     4321 taggaataat agttatgact catgggagtt ttagtgaaga aattataaaa agctgtgaac
     4381 ttattgcagg accagcagaa agaacagcag caattaaact aaataggaat gataatattg
     4441 aagacttaaa taaaaatttt gtagaaaagt taaatgaatt agatgaaggt gacggagttt
     4501 tagtattagc tgacctatta ggaggttcgc caagtaatgt tgcaagttta aaccttaaaa
     4561 aaggtggcaa gtttcatgca cttactggag taaatcttcc aatgctactt gaagctttaa
     4621 ttaatagaga gggaaaaagt ttagaagagt tagcagaagc atgtattgaa gcaggacaaa
     4681 ctggtataaa caatattaat aaagttctta gctcaatgta atagaaaaag gagtttgatt
     4741 aaaaatgtct ttagtaaaat attgcagatg tgatgataga ttaatacatg gtcaagttat
     4801 atataaatgg gttaagcatc taggtgtaaa aaagatagta gtagtagatg atgaaacaac
     4861 caatgatgtt attgctaaag gtttgataaa aatggcagca ccaaagaata ttgatttatc
     4921 aatattaact gtaagtgaat caaggagata tttttataat aatcaagctg atgataacgt
     4981 ttttgtatta attaaaaatt tagatactgc aaatagaatg atagaagaag ggattaatat
     5041 caaaaaactt attgttggaa gaatacctac aggaatagga aaaaagaaaa tatctcaaaa
     5101 tgtatacatt aataaaaaag agtttctttt aatagatgaa tttattaaaa agaatattaa
     5161 tgtatcaatt caaatggtac ctgatgaaga agaagtagaa ttaaaccaaa atattaatcg
     5221 ctataaagga gagtttattt agcaatgaat aaatataagg taatcatact gtgccatgga
     5281 acttggggaa aagtcttagt agaagaaaca aataaaaact ttggattgtc aaatcaatat
     5341 gaagttttat cactaagttc tgaaaaagat gtttctgtat ttatgaaaga ggttgaagaa
     5401 gtagtagata aagaagatgt gaaaattata atatcagatt tatatggagg atctacatca
     5461 agtgttgcaa tagctgttgc tataagaaga ggaatagatg caataaatgg acttagctta
     5521 cagacaattt taatcgtaga tgaagaatta agcaaagaag ataaattaca tacattacca
     5581 gaaagaatcg tcaaaaaaaa taataacctt tgtgtggatt taattaaaga atttaaaaaa
     5641 atataaatta tgaggtgaat ataatggcaa aaataacatt agtaagagta gaccacagat
     5701 taattcatgg gcaagttata acaaaatggg taaaaatcgc tcaagctcaa aaaataataa
     5761 tagttgatga cttcttaggt caagatgaat ttatggctga catatataaa atggcagcac
     5821 catcaggagt agaagtagtt attttaacag cagaagatgc gggacaagca ttccaaaaca
     5881 acactttagg agataaaaat atatttattc tatttaaaaa tgttgatatg gcaaataagg
     5941 cttataaagc tggacttaaa tatgaaaaga ttcaattagg aggtattcca aatgaagcag
     6001 gaaagaaaat ggtgtttaca gctgtttcat taggaaatga ggatgtagaa caacttaatg
     6061 aacttaatga aaatggggtt gaaatagtcc tacaagttat accagaggaa tcatctatga
     6121 catatgaaaa tgcgttaaag aaatttaaat aaaaaatata aattaggagg aattataaat
     6181 ggaatctgtt ttgatgttgg caattgtaac aggattatgg tattggtttg cagcaggtct
     6241 tgcagggtat acccttttct caacactaaa gtctccttta tttataggtt ttagccttgg
     6301 attactttgg ggtgatgtaa caactggtat gattgttggt gcaagtatag aaatggttta
     6361 tctaggaatg gtcgcagcag ggggaaatat tccatcagat aaatgtctag ctgctcttat
     6421 tgcaatacca gtagcacttc aaactggtgt taatgcagaa gttgcagtat ctattgcggt
     6481 acctttaggt gttataggag tattagttaa taacttaaga agaactggta atgctgtatt
     6541 ggttcataag gcagataagt atgctgaaga aggtaataca aaaggcatct ggagatgtgc
     6601 aacactttat tctttaatat ttgggtttgt tttaaggttt ccaatagttt ttgtatgtaa
     6661 cttttttgga gcagatttag ttcaatcatt attagatgtt ataccacaat ggttaatgaa
     6721 tggattaaca gtaatgggcg gtatattacc tgcattaggt tttgcaacaa caatatttac
     6781 tataggtaaa aataaatttt taccaatgtt tattatagga ttttttatgg ttcaatattt
     6841 tgaaatatca attactgcag ctgcaatatt tggtgtttgt atagctcttt taattacctt
     6901 tatgaaagaa gacaaaaggg taggtgaagt ataatgcaag aaataaaaaa taaagaagtt
     6961 aaaaatggac aaggtccaac tgaagttaat aagacaagag tacttacaaa gaaagatgta
     7021 acaaaaacat atctaagatg gtggtggaca gcagaattat ccaactcttt tgaaagaatg
     7081 caagcattag cagtttgtgc aagtttcact ccggctttag aaaagttata taagagaaaa
     7141 gaagatttag tagatgcgtt aaagagacac ttacaatttt ttaatactca agctatatgg
     7201 ggaggattaa ttcacggtac agttttagct atggaagaag agaaagctac tgaaggaaaa
     7261 atcccaggag aagttatttc aggtgttaag aatggtctta tgggaccttt ggctggaatt
     7321 ggagatactt tagattttgg tacatttcaa acaatattct tagctttagg tgcttcattt
     7381 ggagcagaag gaagtgttat aggtgcattt ttcccaataa tgtttagtat attactattt
     7441 tgcgaaggtt attacttatt tcatttagga tattctttag gtagagattc aattaagaaa
     7501 attctatcag gtggtattgt caataagata attgatggtg cttcaattct aggaatgttt
     7561 atgatgggag cattatctgc aactacagtt aagctttcaa ctccgctatc atttgatatt
     7621 ggtggtaaag caattgttgt tcaagataca ttaaatatga ttgctccagg tttattacca
     7681 cttggtgttg tattcttcgt atattgggga atgaaataca agaagtggac aataactaag
     7741 ttattagtaa ttttagttgt attagcattg gtagggtcat tcattggaat attctaattc
     7801 acagtgatta aaatatagaa tttaatttta ggaggagaaa gaaatgtcag aaaaaatgta
     7861 tacagaaaag gaatatttag aaggaattag aggagcaaca ggagaaagag cagtatggtt
     7921 ctatcttctt atgaaagaag ctgaaaaatt aggagctaat ccagatgata tatgtaaaga
     7981 agcaatatat ggatttggta aaatgagagg tcaaaaatat aacgtagcag atactccagg
     8041 aaaaatggca gaaatgttat ataacagtaa aggacaaaaa gtgtttgaaa tggaattagt
     8101 agaaaataca gatgagaatg gcgttttaaa attccatcac tgtccattag atgctgcttg
     8161 gaaagaatat ggattaacta aagaagaaag aaaagaaatt tgtagattag cttgttatgg
     8221 ggattatgga agagttgact gcgcacaagg tgttaaatta gattttgctc aaaaatgtgc
     8281 tcatgatgat gaagtttgtg aattagtatt tacaaaaaaa taatttttaa tgctaaaagc
     8341 ctgttcttta aggacaggct ttaaaaagat agaaagtagg ttgatttatg gatataagca
     8401 gaagtgtaga taatagttta aatagaacca tagaatttct aaaagaattg ataaaaattg
     8461 attcacaaca aggtgaacct atttcacaat gtccttttgg tataggacct aaaaaatctt
     8521 tagataaaac tttagattac tgtgctagtt taggttttag tgttaaaaat attgataatt
     8581 atattggata tgcagaaatt ggagagggag aggaattaat agggattcca atgcatttag
     8641 atatagttcc accaggagag gggtggagtg tagacccatt ttcgggagca gtaattgaca
     8701 atattattta tggaagaggt gtcatagata ataagggtgc tgtatctatg cttatacatg
     8761 tattgaaaaa catagaggat atgtatccta caattaataa aagaataaga ttaatttttg
     8821 gtacaaatga ggagacaggt atgaaatgta tcaaatatta cttagataaa ggtgaagaaa
     8881 ttccaagtat gggatttact ccagatgcta tgtatccagt ggttaatgga gaaaaaggaa
     8941 gggttcatat aaggatagaa aaagaaatta aaattgacaa aagtaaacct tacataatag
     9001 taaggggagg aactaaagaa aatgttgttc catctcattg tactgcaaaa attattaatg
     9061 gaattatttc agagttaact actaaaggag tagctgtaca tgcaagtaat cctgaaaagg
     9121 gagaaaatgc tatatctaaa atggtaataa agatagttga ggataatatg gattttcagc
     9181 atagagaaga tatagaatta gtttcaaaat acctttgtag tgattattat ggagatgcat
     9241 tggggattaa tcaatatgat gaggtattca aaaacactac cttaaattta ggaatattaa
     9301 aagtaaatga ggaaaaaatc gtatgtgagt tagatataag gtatggtaaa aatatagttt
     9361 taaataacat aatagataga ttcaaaaagg ttttttgtaa tggttggaaa atagaggtta
     9421 ttgctcataa agacttacat tatgtggatg agagtaattt agtacttaaa aaattattag
     9481 aagcctatga agaagtaaca gatgaaaatg gatatacaat tgctatgggt ggtggcacat
     9541 atgcaagttg gtttaaagat atggtggcgt ttggacctaa gttcttagcg tataaaactg
     9601 gtggtcatgg agtagatgaa agagtaccaa taaatcatat acgaaagaat atggagatat
     9661 atactttggc tttaataaaa ctattagaat tgtaaaagaa gaagagactt tatgtgcaaa
     9721 tttacagata tcttaaaaag agagataaaa cgagttcaac cttatttaaa tgttcaacac
     9781 catcaaatgg ggctgtctca aaatagagat aagcctctta cttattgttg aaatgatgaa
     9841 aatatatttt acttcataca aaaaagagtg ccttatgaag taaaaagtta attttgagac
     9901 accctcattt gatgatgttg aagagaaaat aagtatgaaa ttattaaaaa agatgatttt
     9961 aaaaaagtta aggttgaaaa gaaaagttaa ttaaatggaa ttagataaat ggagaaggat
    10021 gtatactatc taataaaata acaaaagagt gttataaagt tggttatatg attagagaaa
    10081 agtctattga tacttatcca gatagtggat ggggatttat gacttgggat gaaaatggag
    10141 aataataaaa attatagttt atacagttta ataagatata tgtacaagca gttaatctaa
    10201 atgattgact gcttttcttt tatagatttt tatataatag acaaatacca atacatgata
    10261 gttgcctgtt ataattagag gaataaatac gaataataac tttataaaag aattaaatgg
    10321 aaaatcgaag agttatattc agtattttaa aaagaatatg aaatgagaaa tgaaaataag
    10381 gtgtttatat taaaagaggt tttacacaaa atatttaaaa acgtgataaa taaaaactgt
    10441 atttagatag attaactatt agttttatat aatatggatt ttatttacaa agtttacata
    10501 ttttacaaaa gagattaaag ataaatttaa atatatattt tatatacttg tttatttgtt
    10561 tctctgtggt tgattttttc gtcaaaagtc aacttcaaat cgcttgttag ctttacatgt
    10621 ttaaggatat aattatacat aaggagggat tgacatgaat gaattaaaca tcgcaaaaac
    10681 gctgatttta aagcgtaaag aaaaaggaat tacacaagat gaacttgcaa attatatagg
    10741 cgtttctaaa gcttctgtat ctaaatggga aactggacaa agctatcctg acataacctt
    10801 tttaccgcaa ctcgcgacat atttcaacat taccgttgat gagttaatat gttatgaacc
    10861 tcaaatgatg aaggaagata ttaataaact gtataataaa ctgtgcaaag actttacggt
    10921 taaaccattt gatgaagtca tggatgaaat aagagaaatc ataaaaaaat attattcatg
    10981 ttttcctttg atttttcgga tgggtctttt aatagttaat cactatgata ttgtagatga
    11041 aaaaaagcgt gaactattaa ttagtgaagc attagaaata tttattcgta tacaggaaac
    11101 ttgtaatgac atagatattt gccgtcaagc aaaaagtatg gaggcaactt gttatatatt
    11161 gttaaatcaa cccatacaag tgattgattt attgcaaaac agcaattttc ccatgataaa
    11221 tgaatctata cttcttgcac aggggcaaat gatgaatggc caaatggatg aagcaagaga
    11281 aacatttcaa cttggtgcat atcagaacct tatatcatta gtccaaaacc tagtgggtat
    11341 tttgcaaaat gcagataaat tacaaatgaa ggaaatagaa agacgtattc tagcaatttc
    11401 agatatattt gagcttgata cattatctcc tgctattatg ctttcttcat atttaacaca
    11461 ggcacaaatt aatttaatac atggtgataa tgaaggagct attaaatcat tacgaaaata
    11521 tgtagattta gcaacacgtg atatataccc aattataata catggggatg acttttttaa
    11581 taaacttgac agatggattt ctgaaattgg aacaggtatt acacgtgatg atacaatcgt
    11641 aaaagcaggt attgttgctg ctattaaaaa taatccaatg ttttctgtat taagtgaaaa
    11701 caaagaatac aaatttctta tagaaaaatt atctttattg gaggaataag attatggaaa
    11761 atttgatgga atacttacca cttttggttc ctgttattat tttagattta atacttataa
    11821 ttactgcact tgttcatgtg ttgagacatc caaattataa aattggaaat aaggcaatat
    11881 ggattattgt agtactgttt attagtttaa taggaccaat tttgtatttt acaataggaa
    11941 gaggtgaaga atgatgaata ttgtctcaat aaatggatta tcaaaaggtt ttggtaatcg
    12001 aaagataata gataatttaa attttactgt accagaaggg tcagtctttg ggtttgtagg
    12061 taagaatggt gcaggtaaga ctacaacaat gaaaatggta cttgggttac ttaaaccaga
    12121 tagtggaact atagatgttt gtggtgagaa agtgacctat gggaaaacaa gttctaatcg
    12181 tcatgtaggt tatctgcctg atgttccaga gttttacaat tatatgagac cacttgaata
    12241 tctttctctt tgtggtgaaa ttacgggact ttcaaaaaaa gaaatacaga taaggagtga
    12301 agagttgtta tcacttgtgg gtcttagaaa tgaaaagaga cgaataggtg ggttttctcg
    12361 tggaatgaag caacgacttg gtatagctca agctttgctt tcacgcccca aattacttat
    12421 ttgtgatgaa ccaacaagtg cacttgaccc tgttggtcga aaagaaatat tagatattat
    12481 gcttaaaatc aaagactcaa caactgtaat attttcaaca catatactat cagatgttga
    12541 aagaatctgt gaccatgttg ctatattaaa caaaggaagc attgccctta gtggtacact
    12601 ttcagaaata aaaagtatgc acggaaagga tagactttta ctggagtttg caagtaatga
    12661 tgaaattcaa aagtttaagt ctagtgatgg tattaaatcc ttactaaaag attcagaaga
    12721 aactaatatg gaaattgttt tgcatggtaa agatataaaa gcaatacaaa aaacagttat
    12781 atctacactc gcagaaatga atctttgtcc agtaaagatg gaactaatag aattatcact
    12841 tgaaaattta tttttggagg tagtaaagtg agagaataca tagcatttac aaaaaaagaa
    12901 tttaaagaga atttaagaaa ttataaatta tttagtttaa ttattttatt tctaatattt
    12961 ggtataagta gtcctatttc tgcaaaattt atgccagact tgattgctca ttttgcaccg
    13021 actttaaaag ttactgctgc accaactgct ttagattctt ggacacaatt ttttagcaat
    13081 atctctggtc ttggtatgag tttaactcta attatttttt gtaatatttt atcaaatgaa
    13141 tattctaaag ggacacttgt tattatgctg actaaaggtt tatcacgttc atctatagta
    13201 ttgtctaaat tctctgttac ggtgattatt atgacaattg gtttttggtt gagtttttta
    13261 tttgcttatg gatatacaat gtatttttgg ccaactgcaa atcttaatca tattatattt
    13321 tcagcattta atttatggct tataggaatt atgtatatta gtgtattaat tcttgggtgt
    13381 gtactattta gaccagcatt tgccagtgtt ttacttgtat tggtggcaac tcttttattg
    13441 agtttaattt ctattcctaa acagattgca ccttatactc ctaatttctt gatgtcaaaa
    13501 aatatagact tgatttcagg gaaagtggca atgccagaat ttattattcc aattattata
    13561 acagttctta tttctgtagt atgtttacta gcagctgtta ttttatttaa taaaaaacca
    13621 gtttaataat acctttatca caaggtaaag taatcttatg ttgttaaaaa ctacacctaa
    13681 aaatcaaaaa gacttggact taagtttcaa gtctttttga tttttaatat atagaattaa
    13741 gtgtagaaaa taata
//
LOCUS       DAEOTL010000096        13676 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEOTL010000096 DAEOTL010000000
VERSION     DAEOTL010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13676
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.097"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            60..200
                     /locus_tag="KRH82_003296"
     CDS             60..200
                     /locus_tag="KRH82_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656559.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(375..695)
                     /locus_tag="KRH82_003297"
     CDS             complement(375..695)
                     /locus_tag="KRH82_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBG8656560.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(815..1552)
                     /locus_tag="KRH82_003298"
     CDS             complement(815..1552)
                     /locus_tag="KRH82_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBG8656561.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1767..3590
                     /gene="acd"
                     /locus_tag="KRH82_003299"
     CDS             1767..3590
                     /gene="acd"
                     /locus_tag="KRH82_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBG8656562.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3805..8103
                     /locus_tag="KRH82_003300"
     CDS             3805..8103
                     /locus_tag="KRH82_003300"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBG8656563.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8307..8768
                     /locus_tag="KRH82_003301"
     CDS             8307..8768
                     /locus_tag="KRH82_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBG8656564.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8798..9952
                     /gene="nusA"
                     /locus_tag="KRH82_003302"
     CDS             8798..9952
                     /gene="nusA"
                     /locus_tag="KRH82_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBG8656565.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            9959..10240
                     /locus_tag="KRH82_003303"
     CDS             9959..10240
                     /locus_tag="KRH82_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBG8656566.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10230..10541
                     /locus_tag="KRH82_003304"
     CDS             10230..10541
                     /locus_tag="KRH82_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBG8656567.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10563..12503
                     /gene="infB"
                     /locus_tag="KRH82_003305"
     CDS             10563..12503
                     /gene="infB"
                     /locus_tag="KRH82_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBG8656568.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12546..12926
                     /gene="rbfA"
                     /locus_tag="KRH82_003306"
     CDS             12546..12926
                     /gene="rbfA"
                     /locus_tag="KRH82_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBG8656569.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            12907..13584
                     /locus_tag="KRH82_003307"
                     /pseudo
     CDS             12907..13584
                     /locus_tag="KRH82_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5458 a         1554 c         2576 g         4088 t
ORIGIN      
        1 agatattata attaattaac agtttttgta agtatttgac aatagagagg gtgtaacaaa
       61 tgggaataat agagtcagca tcaaaattgg ctgagatggt tcatttattg gctgttgaaa
      121 aggggataac tgatatagaa gcatgggatg aagctgtgaa agaatacagc aaaatttatg
      181 aagaaagaag aaatgaatag aatgataaaa aatgaaaact tgatgataaa aaataacttt
      241 atttaaagaa attcaatttt tatagaagta ttaaaaataa tataaataaa aagatggtat
      301 ttcaaatgta agtaaaaaat cattttggga taccatcctt attatttatt ttaataatat
      361 ataagtaata aatcttactt atccatattt tttatgtaac ctcttttttc tagctttttt
      421 atatgctcct tacgtatttc atcaagatta ataccatatt gttcttctag cttaaacatc
      481 atagtaacac atgtctgcgc tacatccatt agttccttag cagttttctt tataatatca
      541 acttcatcta aatcattatt ttctccactt agatttctga atttacctat acattcagct
      601 aattcacctt gttcttcacc cattttgata aatgtagatt ctagtgttgg gtctaaatta
      661 ttaagctctg gtaaagatat agtttttagt ttcataaaag ctcctttcaa gttattcgta
      721 tttatactaa aacatcataa caaaaataat actaaaaaaa aactttaaat tcaacataaa
      781 aacttacata tataataaaa atcgtgaaat aaatctatat ttgtcttaat acagcctcat
      841 ataaaacttc tccaataggt ttatttatta caagagaagc tgacttatca tagactgtat
      901 ttgctttatt aataagagca atataatcac ctttgtaata atctataaaa cttgctgctg
      961 ggtacacagc taatgatgta cctcctataa tcaataaatc agcattactt atagcagaaa
     1021 ttgttttagt aatgacatca ctgtcaagag cttcctcata aagtactaca tctggtttta
     1081 ctatagaacc acagttgtca cagtaaggaa tattacctcc cagatttaac atagattcta
     1141 agtcaaaaaa cttaccacat ttagtacaat aatttctatg tacagaacca tgaagttcta
     1201 gcacattttt acttccagcc atttgatgaa gtccatcaat attttgagtt atgacagctt
     1261 taagcttacc catttcttcg agttttgcta aagctatatg agcattattg ggttttgcat
     1321 taggatatat taatttatcc ttataaaatt caaaaaattc ttctggatat ctaacaaaaa
     1381 aagtatgtga aactaattgt tcagcagtaa attgtttatt gagtttttgg ctaaataatc
     1441 cagtagaact tctaaagtct ggaatattag attcagttga aacacctgct ccaccaaaaa
     1501 atacaatatt attgtgatta gctattaagt cttttaagct atttgcatcc atagttacac
     1561 ctccaaatta ttatatataa attgtactac atattaggtc gtttatgttt tattaattta
     1621 aataaatata tagtttaata agttaaataa agggaatata aataaaatgt atacagagta
     1681 taaatagaca atatttacta aaataacaag ttgtcgtata attatattaa aattgtttta
     1741 gtgtataaga agggcggggg aagtacgtga agaaaaaagc agctttagca acattggcta
     1801 tgttaccctt aggtgtggta aatgcacatg ctgatggaga tataggtata gtgactataa
     1861 attatttaaa tgtaagaaat gaaccaactg ccgaaagtag catagccttt gttgctaaaa
     1921 aagatgataa agttttgatt aaagactctt ctaatggatg gtataaaata aaagctgaat
     1981 ctggacaaga aggttgggct tcatcaaaat atatagcaaa atcaaatagt gactctttaa
     2041 gaacgtctac aaataaagaa aaacaagtta tttcaaatag tttaaatatg agaaatggag
     2101 caggtacaag ttacagagta ataactgtac taaaaaaagg tcaaaaagta gaagtaatat
     2161 cagagagtaa tggatggtct aaaatcaaat atgatggaag actaggatat gtatctagct
     2221 cttatttagg agacgtttca aactcaacta ataaatcaaa aactaaacaa gtgaatacaa
     2281 cttcactaaa tgtaaggagt ggaccaaata caagttatgg tttgttaggc aagttgccaa
     2341 aaggaagtaa agtagaagta atatcagaaa gtaatggatg gtcaaaaata aagtataatg
     2401 gaaaagatgc ctatgtatct agtatgtact tatcggatgt aagtcaaagt aattcagaca
     2461 attctagtca aagcaatgat aaaaagaata ctgataaggt tgtaaataca gcttctttaa
     2521 atgtaagaag tggaccaggt tctacatata gtaagttggg aaaagtttat aaaggaagta
     2581 aagtaactgt actatcagaa agtagtggat gggctaagat taattttaac aataaagaag
     2641 catttgtagt aggcaattat ttatctactt cagcagatac ttcaaataat aactcaaata
     2701 gtaactctga taacagttct aatagtaatg gcaataattc ttcatcatca ggtcaagtaa
     2761 atggtatgtc aggtataagt ggggctaaaa ttgattataa atctttgagt tatactttag
     2821 aatctcatat aagtaaacaa gttgagaaag cagcatcagg aggaaatgtg atagctccaa
     2881 gtaataggaa aagcactcca agtcctgaat ttagtacttt ttcagctcaa agaacaagct
     2941 catttgtaaa tgcaagttca agtgatatag aatattattt aaatcctaag aattttacaa
     3001 atactactaa aggtatgatg cagtttttaa agattaacag ttatagagat ggtatttcag
     3061 aatcaagtct taactcgtat cttaatggtt tatcttctag tgtatttaaa aaccagggag
     3121 cagcctttat aaatgctgcc aagaagtata atatagatgt tgtatatcta gtatctcatg
     3181 ctatgtggga aactgcttat ggtaagtcta cacttgccca aggtcaaaca ttaacatctt
     3241 ataagggaca acctcttagt aagccagtta aagtatacaa tttttttggt ataggagcaa
     3301 tagataaaag tgctaatgtt tcaggtgcag aagcagcgta ttccaatggc tggactagtg
     3361 tagaagctac aatagatggc tctgcaaagt ggatatcaca aaattacgta aatagttcta
     3421 agtacaatca gaatactatt tacaagatga agtggaatta tgattataca tggcatcagt
     3481 atgcaactga tgtaaactgg gctaatggaa tttctggaat tatggaaaat ttaattggtc
     3541 tttatggagg aggaagtagt ttggtttttg aagttcctca atataagtaa tacataaata
     3601 aaaaatatag actatgggta gttttcattt tatttaaatt atctatagtc tttttgtata
     3661 taatttataa tctgtaaatt taatgttaac aaaactttta tgttataata ttaattctaa
     3721 gtaaatataa gtgagtaatg ggtagaaata gataaaaagt ggtaataata tatataaaga
     3781 taattttgag aaaggaggat atatatggaa agtattaagg aatatttgga taagttagaa
     3841 attaataata gtggtcttgg aaagcaactt aaagaagttt atataaatag agtagtttat
     3901 tttaaggaag ataagatagt ttatttttat ctaacttcta aagatattgt ttctcatgaa
     3961 cttttagata aatttaaaga agaattgatg tataaactcg attattttaa agatatgagg
     4021 atgaagataa gatttactgg tcttgaaaga aaatccaata aagatgttat aaaaaaatat
     4081 tggaataata tattgtatat attaaagtat ctttgtccat ctattgcagg gtggtataaa
     4141 caagtagaat ttctttgttt agaagaagaa ttaaaaataa aacttccaaa aggtatattt
     4201 tatgagcgat taatgaaaaa aaatgtaact tatgtactta aaaccgtgct tagcgaagag
     4261 ttgggattag atttaaatat aacaatagaa aaagctgttg atgaaaaggt aaataaagaa
     4321 agactcataa gaatcaatga tagagaaatg gaagaaaaaa ttagggcttt agaaattgga
     4381 aaagttaata actgtgaaga aaatgaagag gaaagttatg tcattaagtc tgatgtagat
     4441 gaaaatttaa tctatggaga taatgcaaat gctatgattg aaaatatagt tgaattaaat
     4501 gcatcttctg gaacagttgc agttgttgga gatatatttg atgttgacac taaagaactt
     4561 aaaaacggaa aaatacttat gatagcttca attacagatt atactagctc aataagctgt
     4621 aaactttttt taacagatac aaataaggat ggagtacttg aaaatgttaa aaaaggagca
     4681 tacttaaaaa tcaagggtga catagtttat gatacatatc aaagagaaat tagtatgatg
     4741 attagtggga taagaaaaga aactagaata gagagagaag ataaatcaga ggaaaaaaga
     4801 gtagaactcc atgcacatac acaaatgtct tctatggatg ctatttgttc tgttaaaaag
     4861 cttgtagagc gtgcagccaa atggggtcat tctgctattg ctataacaga ccatggtgtt
     4921 gtacaaggat ttccagatgc tatgaatgca ggtaagtcaa ataatataaa aatactttat
     4981 ggagtagaag ggtacttggt tgaagatgat tctctcatta tagaggatgc aaatgataaa
     5041 gaactttcgc agacatttgt tgtatttgac atagagacaa ctggcttttc taatacaaat
     5101 gataaaataa ctgagattgg tgctgtaaaa atagaaaact ttaagattgt agatagattt
     5161 agtgagttaa taaatcctga aaaagatatt tcttataaga tacaggaatt gacaggaata
     5221 actaatgaat taattaaaga caagccaacc attgaagaag ttcttcctaa gtttatggaa
     5281 tttgttggag atagtgtatt agtagcacat aatgcagagt ttgatactgg atttatatcg
     5341 caaaaatgta gggaacaagg cttgttatat aataacaaaa aagtagatac acttatgtta
     5401 gcaagagtaa tgttaccaaa cttaaaaaga catagattaa atgtcgttgc aaaagaactt
     5461 ggtattcctc ttttaaatca ccatagagca gtggatgatg ctgaagctac agcacttata
     5521 tttaataagt ttttgcagat gcttacagaa aaaggtgcaa aaactctaag tgatgtaaac
     5581 aatatacttg gaaagattga ttacacaaag cttagcacaa atcatataac cttgatagca
     5641 aaaaattcta taggtataaa aaatttatat aaaataattt cagatgcaca tgtaaatcat
     5701 ttttttagag caccaagaat ccttagaagt gtattaaatg aatataaaga aggattaata
     5761 attggttcgg cttgtgaagc tggggtggtt tttcaagctg taaagaaaaa cgtgtctgat
     5821 gaggaaatga aaaaaataat agatttatac gattatattg aagtaatgcc tatagataat
     5881 aatagattta tgattgataa aggagaagta aaggacgaag aagagttaag ggagttgaat
     5941 aggaaattaa ttgatacagc caaaaaattt gacaaaattc cagtagctac tggggatgtt
     6001 cattttttag acaaacatga agctgtctta agaaaagttc ttaaatattc tcaaggtttt
     6061 aaagtagatg aagaagaaac ttatttacat tttagaacaa cagatgaaat gttggaagag
     6121 tttagttatc ttggagaaga attggcatat gaagttgtag ttgaaaatag taatctgatt
     6181 gccgatatgg ttgaagatat aaaacctata ccagatgata cttatcctcc aattatagag
     6241 ggctcagatg tggagttaag agaaatgtgt tacaaaaaag ccaaacgaat ctatggagac
     6301 ccaataccag aaatagttca aaaaagactg gatagagaat taaattcaat aataagcaat
     6361 gggtatgcag ttatgtatat tatagctcaa aaactggttg caaaatctct ttcagatgga
     6421 tatttagttg gttcaagagg ctcagttggc tcatcttttg cagctactat gagtgatata
     6481 acagaagtta atcctcttcc agcacattat atttgtgaaa acgaagactg taaatattca
     6541 ttcttttatg aaataggtga atggggctca ggtgttgatt taccagacaa ggattgtcca
     6601 aagtgtggaa gaaaacttgc taaaaacggt catgatattc catttgaggt tttcttaggt
     6661 tttgaaggtg ataaggaacc agatatagac ttaaatttct caggaaatta tcagccaaca
     6721 attcataaat acacagaaga actatttgga gaggggtatg tatatagggc tgggactata
     6781 ggtactgtag cagaaaaaac agcttttgga tacgcaagaa aatatgtgga agaaaataat
     6841 ataagtgtac caaatgcaga agtacttagg ctttcaaatg gatgtactgg agtaaaaaga
     6901 acctcaggac aacatcctgg tggagttatg gttataccag actataaaga tgtatacgat
     6961 tttacaccta tacagtatcc agcaaatgat acttcttgtg gtgttataac tactcacttt
     7021 gattatcatt caataagtgg tagaatactt aaacttgata tacttggaca cgacggtcct
     7081 accattataa ggatgcttga agatatgact ggaataaata taacagaaat tcctttagat
     7141 gataaagaga ctatgtctct atttacatct acagaagcat taggtgttac accagaagaa
     7201 ataaactgtc ctataggttg ccttgctgta ccagagtttg gaactaagtt tgtacgacaa
     7261 atgttacttg acacaaaacc tactacattt gcagaacttg tacgtatatc tggtctctct
     7321 catgggacag atgtttgggt aaataatgca caagacttag ttagagaaga tatagttgga
     7381 ttaaaagatg ttatatctac acgagatgac ataatgaact atttaatatt taaaggatta
     7441 cctcccaaaa tgagttttac aataatggag agcgtaagaa aaggtaaagg tttaaaacca
     7501 gaacacattg aagaaatgaa aaaaaataat gttccagaat ggtatatagg ctcatgtaaa
     7561 aagataaagt acatgttccc aaaagcacat gctgttgctt atgtaatgac atcatttaga
     7621 attgcatatt gtaaagttca ctatccagaa gcattttatg cgacttattt tacgacaaaa
     7681 gttgaggatt ttgatgcaga tttaattgtt aaaggattag atgctataaa atcaaaaata
     7741 aatgaaattg agtcactggg aaatgatgca accacaaaag aaaaaggtat gttgaccgtt
     7801 ttagaagttg ctcttgaaat gtatgctaga ggaataaaat tattaccagt tgatatatat
     7861 aaatcagatg caactgagtt tatagttgta ggagaaaaaa cattacttcc accaatggca
     7921 gcaatacaag gtcttggagg aaatgcggct ataaacatcc aaaatgaaag aaaaaatggt
     7981 gaatttatat caaaagaaga tttgagaaag agaacaaaaa tatcaaaaac ggtaatagaa
     8041 actcttacta atcatggttc acttgagaat atgagtgaga gaaatcaatt gtcattgttt
     8101 taagttagcc caaaaagttg caaataaaag aattttatga tatcatagta tagaaaatag
     8161 tatactttgc agaaactaag agtgagacag ctgttctcac tcttttattt taaatatatt
     8221 attaaaaagc tggtttattt ttattaaata tattttattt aagattatat aaactggtca
     8281 tttacaattg aataggagga actttaatga aaaaaaattt agaagctaca attgaggaga
     8341 ttgtaactaa aataacggat gaacatggat ttgaaatggt tgatgttgaa tatgtaaaag
     8401 aagcaggaga atactactta agagtataca tagataaaga agaaggaata tctttaaatg
     8461 aatgtgaatt agttagtaga gaattaagtc caatactaga tgaaaaagac cctataaaag
     8521 aaaattactt tttagaggta tcttctccag gacttgatag agcattaaaa aaagacagag
     8581 attttgttag atatcaaggt agagatgtag atttaaaatt atataaacca ttaaatggat
     8641 gtaagcaatt tgaaggtgaa cttgtaggat taacagaaga taataatata aaaatcattg
     8701 caaatggtaa ggaaatggaa tttaatagaa aagatgttgc tattgtcaga ttagcaataa
     8761 agttttagtg gtatattaaa tagggaggat ataaaaaatg aatcatgaat ttatggaagc
     8821 attagatgaa ttagtagttg acagaggtat agataaagaa atacttatag atactataga
     8881 acaagctctt ttaactgcat acaagaaaaa ctttggttca gcacaaaatg ttagagttga
     8941 atttgataga gacaagggag atataaaagt attttctcaa agagttgttg ttgatgaatc
     9001 agatttatat gatactttct tagaaataga gttagcagat gctagagaga taaaccctaa
     9061 ttatgaatta ggtgatatta tagaacatga agttacacct aaaaactttg gaagaattgc
     9121 agctcaaaca gcaaagcaag tagttgttca aagaataagg gaagctgaga gagaaatagt
     9181 gtataatgaa tttatagaaa aagaaaatga aatagttaca ggagaggttg ctagagcaaa
     9241 taaaaatgtt gtttatgtaa atcttggaag aatagaaggt ataatgactc aaagtgaaca
     9301 aataccattt gagaattata aagcaggtca aaaaataaaa ttctatatac ttgaagttaa
     9361 aaagactaac aaaggacctc aaatagttgt atcaagaagt catccgggtc tagtaaagag
     9421 attgtttgaa gaagaagttc ctgaaatata tgaaggaata gttcaaataa aatctgtagc
     9481 aagagaagca gggtcaagaa ctaaaatggc agtaagatct atagatgaaa aaatagaccc
     9541 aattggagct tgtgttggac caaaaggact tagagtaaaa aatatagtgg atgaacttgg
     9601 cgatgagaaa atagatataa taaaatatag tgaagaccca gcagagttta tatcagcagc
     9661 acttagccca tcaaaagttg ttagagtaga tatagatgaa gatgaaaagt ctgccttagt
     9721 aatcgttcca gattatcagt tatcgcttgc tataggtaaa gaaggtcaaa atgcaagact
     9781 agcagcaaaa ttgactaact ggaaaataga tattaagagc gaatctcaag cagaacaaga
     9841 aatgttaaat cttgaaaatt ccaaagaaat agaagctgag gatgttgaag ctgaatttat
     9901 cgaccaagaa gagttagata cttcagagga taattttagt gaagaagagt aaggagggat
     9961 gattttgaaa aaagtaaaaa aagtgcctca aagaaaatgc atagcatgtc aagatagaga
    10021 ctctaaaaaa gagcttataa gaatagttaa aaataaagaa ggaaaaatat ttttagaccc
    10081 aacaggaaga gccaatggaa gaggagcata tgtatgtaaa agctctgaat gtctaaaaaa
    10141 agctataaag agtaaagcat taaataaagc ttttaaaata gatgttcctg atgaagtcta
    10201 tgataatcta cttatggagt tagaagaata tgaaaaataa taaagaaaaa gtactttcgt
    10261 tcttagggct cgcaactcgt gcagggaaaa tagtgtctgg tgatgattca actttgcttg
    10321 accttaaaaa aggaaaagta aatttgattt taatcgcaga agatgcatca aataatacta
    10381 aaaaactttt taaagataaa tcaactttta gaaatattcc atatctattt ttttcaacaa
    10441 aagaggaaat aggatttgca ataggaaaat ctccaagagc agttgtagga ataaaagatg
    10501 aaaatttttc taaaaagata attgaactaa tagaaattta aaataaaata gggggtgatc
    10561 ttgtgtcaaa aacaagagta taccaaatag cagaagaatt aaatatatca aatgaagagc
    10621 ttataaataa gttagctgaa ttagatataa atgtaactga caaagattca gtattagaag
    10681 gtgaagagtt agaattagca cttgaaatgt taggtgaaga tttatctcaa gaaaatggaa
    10741 atgttataga aatagatgga aagttgacag tacaagtatt agcaacgaaa ttagataaat
    10801 ctccatcaga aataattatg aagcttatga aaatgggaac tatggcaaca ataaatcaag
    10861 agataagttt tgagattgct gccttggctg ccaaagacta tggctttgaa ttaacagtag
    10921 ctgaaagtga tgatacagaa gctttagaaa tagaagcttt aatggaaatt gaagaagata
    10981 aagaagagga tttaaaacct agaccaccag ttgttacagt tatgggacat gttgaccatg
    11041 gtaagacatc tttactagat gcaataagaa aaactgatgt gatttcaggt gaagctggag
    11101 gaataactca gcatataggt gcttcagaag ttaaaatcaa tggacacaaa atagtatttt
    11161 tagatactcc aggacatgag gctttcacat caatgagagc aagaggagca caagttacag
    11221 atatagcaat attagtagtt gcagcagatg atggtataat gcctcaaaca gttgaagcta
    11281 taaaccatgc taaagcagca ggtgtacctt taatagttgc tattaataaa atagataaac
    11341 caggtgcaaa cccagataag gttaaacagg aattagcaga ccaaggatta ttagttgaag
    11401 actggggtgg agaagtaata gcagttccag tatcagctaa gaaaaaagaa ggaatagata
    11461 cacttttaga aatggtatta ttggttgctg aaatggaaga gttaagagct aatccaaata
    11521 aaagagcagt aggaactgtt atagaagctg agcttgataa aggaagaggg ccagttgcaa
    11581 cagtacttgt tcaaggtggt actttaacag taggtgaccc aatcgttgca ggtgttgcat
    11641 gtggtaaagt tagagcaatg ataaatgcaa aaggtaagag agtaaaaaca gcaggaccat
    11701 ctacagcagt tgagatatta ggtctatcag aagttccaca aggaggagac caatttgtcg
    11761 aagttccaac tgataagatt gctagaagtg tagcagcaag aagacaacaa atagttagag
    11821 atgaaatgtt aaaatcaact caaagattat cactagatgc tctatttagt caaatgagtg
    11881 aaggttctat aaaagacctt aatatagtta taaaagcaga tgtacaaggt tcagtacagg
    11941 cagttaaaca atctttagaa aaattatcaa atgaagaagt tcaagttaaa gtaatacatg
    12001 gtggtgttgg agctgtaaca gaatcagaca tattacttgc agcagcttct aacgcaataa
    12061 taataggatt caatgtaaga ccagttccag gtgcagaatc tctaggagaa aaagaaaatg
    12121 ttgatataag aacatatact ataatataca aggcaataga agatatacaa gcggctatga
    12181 ctggtatgtt agaccctgaa tatgttgatg aagaaacagg aaaagctgaa ataagagaaa
    12241 tatataaaat atctggtgtt ggaacagtag ctggatgtta tgtgactaat ggtaagatat
    12301 ttagaaattg taaagtaaga ttagttagag atagcataat aatacatgaa ggtgagcttg
    12361 cagcacttaa gagatttaaa gatgatgtaa aagaagttaa ttctggatac gaatgtggta
    12421 tgagttttgt aaattataac gacataaaag aaggcgatat agtagaagct tatataacta
    12481 aagaagtaga aagaaaatta taaattcgta tcaaagaaaa tcagttagta aagaaggtcg
    12541 atggtatggc atcatataat agaacaagaa ggatagcaga agaaataaga aaagtcgtaa
    12601 gtactatgct tataaatgga gtaaaagacc ctagaataac atctatggtg agtgtaactg
    12661 atgtagaagt tacaaatgac ctaagatatg cttatgtata tgtaagtatt ctaggtggag
    12721 atgaagaatc cacactaaca ggtcttaaaa gtgctggagg atatataaga agagaagtag
    12781 gaaaaaatat aaaacttaga tatattcctg agatagtatt taaacttgat gattcaatag
    12841 aaaaaggaat gtatatggat agccttataa aaagagttaa tgaaaaaaat gctcaacaaa
    12901 atgaggatga aaattatgat gaataatatg gatagtatta taaactatat ttatgagggt
    12961 gactatttta tagttacctc tcatatcagt ccagatggag acaatattgg ttctacactt
    13021 tcaatgtatt atacattgaa gaatttagga aaaaatgtat attatgtact tgatgatgaa
    13081 gctccattaa atttaaggtt tttggttgaa ggtgtaaaaa tctataagtc taatgaattt
    13141 aatatgaaga actattctct aattgcactt gattgtgggg ataagatgag aatatgtgtg
    13201 agtgatgaaa tcaaaaataa tgcatcaaaa ttaatctgta ttgaccatca tgctagtaat
    13261 gattcatatg gagatttaaa ttatgtagat attgatgcat cttctacatg tgaattagtt
    13321 tataatttat tagttagatt tcagcaaata aaagatatta atattataaa tgaagatata
    13381 gcaacatgtt tatatacagg tcttgtaact gatactggaa acttttcgta ttcaaatgta
    13441 catgcaagta gctttgaaat ggcaaaaaat ttacttgttt taggtgcaca aaaaaatact
    13501 ataatacaaa atatatatca aagcaattct tctggttatt acaaattatt aggagaagct
    13561 ctaaagggtt tggagatatt tgattaaaaa atagttacgc acactcgtga ctttagtcat
    13621 gagttagtag ctaaaatagt cagcatatag ggaaacttat atgtagagat aggata
//
LOCUS       DAEOTL010000097        13442 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEOTL010000097 DAEOTL010000000
VERSION     DAEOTL010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13442
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.098"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            220..2079
                     /locus_tag="KRH82_003308"
     CDS             220..2079
                     /locus_tag="KRH82_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8656570.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2371..2970)
                     /locus_tag="KRH82_003309"
     CDS             complement(2371..2970)
                     /locus_tag="KRH82_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBG8656571.1"
                     /translation="MAIELKKGQKINLTKKENSNLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3073..3870)
                     /locus_tag="KRH82_003310"
     CDS             complement(3073..3870)
                     /locus_tag="KRH82_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8656572.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3983..4088)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4180..5166)
                     /locus_tag="KRH82_003311"
     CDS             complement(4180..5166)
                     /locus_tag="KRH82_003311"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBG8656573.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5650..7380
                     /locus_tag="KRH82_003312"
     CDS             5650..7380
                     /locus_tag="KRH82_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBG8656574.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7490..7570
                     /locus_tag="KRH82_003313"
     tRNA            7490..7570
                     /locus_tag="KRH82_003313"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7524..7526,aa:Leu,seq:tag)
     gene            7905..8420
                     /locus_tag="KRH82_003314"
     CDS             7905..8420
                     /locus_tag="KRH82_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBG8656575.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YKNYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8912..9016
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9226..11700
                     /gene="gcvPA"
                     /locus_tag="KRH82_003315"
     CDS             9226..11700
                     /gene="gcvPA"
                     /locus_tag="KRH82_003315"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBG8656576.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11700..13157
                     /gene="gcvPB"
                     /locus_tag="KRH82_003316"
     CDS             11700..13157
                     /gene="gcvPB"
                     /locus_tag="KRH82_003316"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBG8656577.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDPDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         5052 a         1592 c         2207 g         4591 t
ORIGIN      
        1 aaagtttata aattacatta agagtaataa tctataagaa cttatatatt agaaaaaatt
       61 ttgtatatat agaggactct aaagatgaac tatgtaaaac aaggtttata tattctaatt
      121 gtatagaaaa tttattgtaa acgcatgtat attattagaa aaaatagttt gaaggtattc
      181 aataaacata aaaaacaata taggggataa aggtgtttta tgaagagatt tttgaggaga
      241 attatcttag ttttatttat tttgttgatt tttataagtt ttatttctat taaattaatt
      301 cataatgttg gagattatgg aaaattgatt aattatgttg ggattgttcg tggagctagc
      361 caacgtctaa ctaaactaga gatgaatcat caaccaaatg atgaattaat agaatatatt
      421 gatgaaatcc tacaggagtt gattacaggg catggagatt atggtttagt aatcactgat
      481 tgtaatgaat acaatgagga cttactttta ttagaaaaaa agtgggaaga tttaaatatt
      541 gaaattaaaa aagtaagaat gaaagaacag aataaccagt tattaagtat aagtgaagag
      601 tttttttctc ttgcaaatga tacagtgttt aaaatagaaa acttttctaa agaaaaaagt
      661 aattacttaa tgactttaat aataattata tctattatag gtatattagc atgtatcata
      721 ttgattttac aatatagtaa aaaaatggtt agactggaaa aattaaatgt agatttaaaa
      781 aatattgcat ataaagatga actaacagga gtaaatacta tagaaaaatt taaattggat
      841 gcaaatcaaa atatttgtat acataaggat aagaaatttg ctgtattcta tattgatttt
      901 gaaaacttta aatacattaa tgatatattt ggatatgatt atggtgacat gatactgaaa
      961 agatatgcta atcttatgat gaatgacata gggaaatatg aaatatttgc aagagaaatt
     1021 gcagatagat ttgttgcgtt aagatgctat gtagataagg aagatttagt ggtaagacaa
     1081 cgagatgtag acaatgaact aattaatata acaaatgaaa ttaaaaataa acatagtatt
     1141 actgttgtta gtggaatttg ttgtattgaa gatgtaaatg aaaaattaag tatagatggt
     1201 ttaataaata gagcaaattt tgcacaaaaa actgttaaga ataaaccagg tactaattat
     1261 gctttttata atgacagtat tcgtaaaaaa atgattgaag aaaatactat caagagtaga
     1321 atacatgaag ctattgaaaa aagagaattt atagtttatt tacagcctaa agttaattta
     1381 catagtcaaa aaataaattg tgcagaagct ttagttcgtt ggcttactcc ggataaaggt
     1441 attatatctc cagcaatatt tattccagta cttgagaaga atttttttat tgccttagta
     1501 gataagtatg tttttgagga ggtttgtaaa tggattagaa agaggttaga tgaaaataaa
     1561 ccttttgttc agatatcagt taatgtttca agaatacaat tttataacac taaatttgta
     1621 gaaacttatt ccaatataca aaataaatac aggataccta aaaatactat agaaattgaa
     1681 tttacagaga gtgttgcttt tgagaatcaa aaacatcttt tggaaattat acatgatttg
     1741 catgaaaatg gatttacttg ttctttagat gattttggaa aaggttattc gtctttaagt
     1801 gttttaaaag atttaccatt tgatgtttta aagcttgatt ctatgttttt caaggctagt
     1861 ttagataaag ataaagagaa aatagtaata aaaaatattg tacatatgtt aaaagaactt
     1921 aatatcacaa ctgttgctga gggcattgaa tgcaaggaac aagttgaatt tcttagggat
     1981 attgggtgtg atttagttca gggatttgta ttttataaac caatgccaat attagaattt
     2041 gaaaaaatat tggataaaga gtttgtttat aatagctaaa atgtacttta taaaatatga
     2101 actaattaag taaaattatt ttgtactgaa taaattttta ctttatttac agaataatga
     2161 ttatttacag aaaagcgcga aaagtgtatt cctttaagtg tgggatggat agcacaaata
     2221 gaggagaaaa aatattggcc atataagaat gcataataat ataaatattt gaaaggtcag
     2281 cattatataa aaattaaaaa gaaaataaat aatttttcta taaaaaagag actatgagaa
     2341 aatttactca tagtctccta aataatgtat ttattttctt cctgcaaccc attttaatcc
     2401 ccaatgaaat tcagtatcca tttctctatg acctttgaag tatttaacta ctttttcaac
     2461 actgaatgtc tcatcattta cattttctat caatgctatt gaacacatat tatagccatt
     2521 tttatgttca tcaagtttga caactaagtc tgaatcttgt ttttgtttga ttgttacaat
     2581 tccatcagct tcagaccagt tagctacacc ttcgtatata aaagcataaa taagtattct
     2641 ttttatatct tttattttat taccatttat tcttaaattt tctccttgtg tattacttcc
     2701 tgttctgtca tctccatcta attgagcaaa aggtggattg tctaaactac caaaggcatt
     2761 tcctaatgct tgaacagcac cttttacacc atttttcatc tcaaataggc aacccaaatc
     2821 taaatctata ttactgcttc ttaaagagcc aaaaaaaccc tttttttgta ctttttgatt
     2881 ccaatttaaa ttaactaaga tttcacctaa attgctattt tccttttttg taaggtttat
     2941 tttttgtccc ttttttaatt ctatagccat agtaatcttc ctccacaaac atagatttat
     3001 ttaaatggta gcacttaata agtcaatatt caacaagatt agaataataa tattaaaatt
     3061 atactaaata tactaaaaag taggaatcac aatacctttg tatttttctt caattaagct
     3121 tcttgcttta tctgatgtaa gaacatcttg tagaacttta atcttttcac tgtctttatc
     3181 ttcagttcta aatgctaaaa gatttgcata ctcgtcattt ataggagctg tataaattcc
     3241 gtttttcttg gcatcaagac cagcaggtac agcataagta gtatctataa atgcagcagt
     3301 cacatctgga agagaagatg gaatttgagc aatatctaac tctttgaatt gtattccctt
     3361 tggattttct attatgtcct taggactaac taatccatcc cctttaggta acgttaaaag
     3421 tccaatactt tcaaggtatc taaggttctt agaacaagaa gatgggttat tgcttattgc
     3481 aattgtatct ccttttttaa attcatcaac agattttatc ttataagagt aaagtattgc
     3541 tgggcataca tatagttttt taccagccat tattttgtaa cctttggcct taacagcttc
     3601 ttttagataa ggttcatgtt gaaatagatt tgcatcaatt tcaccattat ttaaagcttc
     3661 gtttggaagt atgtaatcat caaagttttt aacttctaaa gtatatcctt tttctttaat
     3721 aagtggtttt aattcttcta ataactctcc tcctggaact aaagtagcac caacaacaat
     3781 ttttttatca tctttagctt tagaacatcc aaccacagct aaagttagta ctagacataa
     3841 taacaaacat aataattttt tgaatttcat ataaattccc tcctgaatat aattgattag
     3901 ttaaaaataa aataccattc tttatcacac tgcaaaataa aaataagcct gagtttaaac
     3961 tcaggcttta aaagctaatt tagactcatc tttcagtata atactgcagg atttagcacc
     4021 aatgtatata aaaatatact ggttgctggg tttcataggg ccagtccctt caccactctg
     4081 gataagaagt atcaattttt aattatgtta taaatattat catgattttt tacgtctgta
     4141 aacataattt tataaatatt ttaaaatctt taatgtattt tatttaacac ctaaaattcc
     4201 agaaactaga atatcagtat cagcacctaa gaaatagtca tttatttcaa tagaatccag
     4261 agtatttctc aaagcatttt cttcatgcct tataccaata agtttatttt ctacaaatgc
     4321 aacatcacat tttccaaaaa aatctccaaa aaattttata ctagttatta tgcctttatc
     4381 aacatttaaa ttaaactcaa catttccacc agaatatttt aattcatttg aaagagtata
     4441 ttttggtgaa ttaccaaaat tccaatccca agtttcgtat tttgatttag taagcttttc
     4501 tatttgtttt atatcatgct cactcaaaca ataattagta ttatcagtat ttgttttaga
     4561 aagataatcc attatagcat ctttaaattc taatatgtcc atttttgaat gtaaatgttc
     4621 acttatattg gttacacgag attttacaga ttttattcct tttccttcaa attttatagg
     4681 tttaaccttt aatgcttttg agaggtcatt tatttcagat gaaaataaaa gagtcccatg
     4741 atgcattact ttgtttttgt agttgtattg agcatttcca gaaaatttct tgccatctat
     4801 aagaaggtca tttcttccag aaaattcggc attgacatct agtgttttaa gtaaatctat
     4861 tatgggctga gtgaatcttc taaaatcact aaaattatta ttgttacaag ctataaatgt
     4921 aaaatttata tttcccaaat catgaaatac agctccacca ccagactgtc tcctaacgac
     4981 aggtatagaa tattctttta tatattctaa atttatttca gaaagtgtgt tttggttttt
     5041 tccaacaatt atagaaggtt cattcctcca taaaataaat aagtcttcat caaaattttt
     5101 tagaagatat tcttccattg ctaaattaaa ataagggttt gttttttcat tataaattaa
     5161 taacattaaa gtagttcctc catagaattg ataaaatttt tattatgaat acaattaatt
     5221 ttataattcg acaataatat aaaaactcct ttaaattaga aattttaaaa actaccttgc
     5281 aaagtttaaa taaataatat atactcaaaa tatgtttaat aaaagtgaat agaagggtag
     5341 aggcgcaata atctatcagt actaataagg agttaagcac agagagttat taggaaagga
     5401 gatattgccg aagttttata atcgatgctt taagattata ttgctggggg tacatagaaa
     5461 atatgtacaa ctgtcacagg tttatttgtg gtgagctatc atttaaggaa ttatattata
     5521 tttattttta ctattgttga tatattgtaa tgtttaagcc ttgagtgttt accactcaag
     5581 gcttttttag ttttattgta acataatacc ccgtacagtt cacaaaatta aaaggagagg
     5641 gagatttata tgaggaacaa aaaaattaat attatttttc tgacgacaat catgttcata
     5701 atgtcaacag taatggtttt tgcagaagaa gatatagaca ctattgcact agccaatgca
     5761 gaaaaatttg ggattttaac tttaatacca ccattagttg ctataatact cgcatttata
     5821 actaaaaacg taataatttc tttacttata ggtattcttt ctggtagttt tataattaaa
     5881 gctagtggta ttaatgtttt tgcgacattt atacaggcat ttttagattt agtagacaga
     5941 gctttagtat ctttagcaga cccttggaat gcggggataa tattacaggt tttggcaatt
     6001 ggaggagtaa taaatcttgt tgctaaaatg ggaggagcta aagctatagc tgaagcactt
     6061 gctaaaagag caaagtcagc aaaagggaca cagcttataa catggttttt ggggctttta
     6121 gtattctttg atgattatgc caattcacta atagtaggtc ctatgatgag acctgttgca
     6181 gataaaatga aaatatcgag agaaaagcta gcatttataa tagatgccac agcagcacca
     6241 gttgctggtt tagctataat atctacatgg ataggtcttg aggttggttt aatacatgat
     6301 gcttttgaaa gtataagtat agatgtagat gcatttggta tatttttaaa tacaatacca
     6361 tttagatttt acaatatatt aatattagct ttcattgtaa tatcagcatt attattaaaa
     6421 gaatttggtc caatgagaaa agctgagata aaatctagaa gtagaaaaat tagtatagac
     6481 cttgatgaag gcgtagaaga gttggatgat ttagctccaa aaaatggagt aaaattgagt
     6541 gtatggaatg ctataatccc aataggaaca ttgataatag ttgcattagc atcattttat
     6601 tatagtggat atacatctat aatgggagga gacgataagg ctctgataca actatttaca
     6661 aattctccat attcttttga agcaataaaa gaagcattta gtgcatctga tgcatctaga
     6721 gcattattcc agtctgcact tgttgcaagt ttagttgcta ttataatggc tgtagtaaaa
     6781 aagattttta caatatcaga agcaattgat gtttggatag atggaatgaa aagtttagta
     6841 atcactggtg taatattaat acttgcatgg tcattaagtt cagtaataaa agagttaggt
     6901 acagctaaat ttttaataca cctattatca ggttcactac caccattctt attaccaagt
     6961 ttaatatttg gtttaggagc aataatatct tttgctactg gaacagctta tggaacaatg
     7021 ggtatactta tgccacttgc aattccatta gcatactcat taaatcctga tatgtcttat
     7081 gtaatagtaa gtactagtgc agttttaaca ggtgcaatat ttggagacca ttgttctcca
     7141 atttcagata caacaatact ttcttcaatg ggagctggct gtaatcatat agaccatgtt
     7201 aacactcaaa tgccatatgc tatatttaca gcagtaatca ctattgtatt tggatatata
     7261 ccagctggac ttggattgcc aatatatata gtattaccag tggcaatagc tgctatattt
     7321 gtaggtattc aaataattgg taagaaagtt gatgaagcgg aaatagaact tgtagaataa
     7381 agatataaat aagtttcacc ttttattatc attattttgt tagtttttag ataattttaa
     7441 aaagttattg aaaataatgg cgaaatatag taaaataaaa gagtgataag cggatgtggc
     7501 ggaattggca gacgcactag acttaggatc tagcgccatt ggcgtggggg ttcgactccc
     7561 ttcatccgca ctttacagta cttaattgta ctgaaaaaaa ctggggttgc tggctttcgg
     7621 agtgggctat cccgttttta tttttttgta tatataatag attggcactt tagtacaaag
     7681 tgcttttttt ataggcaaaa acagtacatt tatttctgtt ttattatcat tcatctatta
     7741 gaatatactt tagttaagaa tgtgttaata agcagtgttc acattcttga taaaatgtgg
     7801 aataatatgt atttttacta agacggaaat gaaataatta aaccattaaa taatattata
     7861 agatgatgaa taagtagata aatcaaattt tgtaggagga tattatggaa aaatatatat
     7921 ggttgtttcc attacttttt atttttcatg atatggaaga gataataggt tttggaatat
     7981 ggcttaaaaa aaataaatca atgcttgata agaagtatcc atttatcagt aaagtttata
     8041 aaaattatag tactgaaggc atggcatttg ctgtgtttga agaatttatt ttatgcatta
     8101 ttttctgtat acttacagtt ataacagaga atcagtatgt atatctacta tggttaggta
     8161 gttttatagc atatacctta catttggtaa ttcatatagg gcagtcaatc ataataagaa
     8221 aatatatacc ttcacttatt accagtatca tatgcttacc aataagcatt tggtgtataa
     8281 gtaagagtat ttatatagtt gattgtgaaa tgagtacaac aattctgtac agtataattg
     8341 gcattataat tgtagcattg aatttaaagt ttgcacagtc gctgattgga aaatttacaa
     8401 agtggatgtc aaacatataa attttagttt attggacagt tcaaggaatc agaaattgga
     8461 attttatagt attaatattt tatagtatta atataatgta taaaatttta tagcaatgta
     8521 tttcataagt ataaagtgac tagaatttta agaaatatac aaattctata aaaactaaat
     8581 aatttcaagt atattttaaa aatcttattt ttcacaagtt taaaattgta aacgatttca
     8641 tcaagtctat gaatatactt ttaacatgtt atagtaaatc tcaatataaa tttacatttg
     8701 gttctttgtg tgttatttta ataataaatt aagtgaaaat gttattttac attaatatat
     8761 aatatctttg cataagagtg aataatataa aagagaaata attgataata aaaacttaac
     8821 aaaaaaatta atacataaaa aaaaataaat ataatgtgtt gacatttaat tgaaatattc
     8881 atacaataaa attgaaaata aatatttcca aatgagatta gcgagagagt cctttatacg
     8941 aaaaggcgcc gaagaagaaa tttaagaaat gccaattttt agagaagctt tcaggcaaaa
     9001 atatcgctaa ttgatgggac tctggagaga cttaagttaa gatactataa gtcaccgaag
     9061 aagcaaaata atattaaatt attaaatctt tcaggtatac aaacagggat atataggcta
     9121 ggattatttt ccatgctgat atatcttttt tttatgaaaa agtacaggaa ataatatcaa
     9181 agttacttaa atacagtagg tctaattttc tagggagggt tatatatgaa tgaattgaaa
     9241 agagtatctt tgtacaatat acacaaagag cttggagcaa aacttgttga atttgctggt
     9301 tgggaaatgc ctttagaata tgagggtata aataaagagc atgagaaggt cagaaaaagt
     9361 gcaggtatat ttgatgtatc tcatatggga gaggtacaga taaagggagc agagtcagaa
     9421 aaatttatac aaaacctagt tacaaatgat ataagcacat taaagataaa tgacattata
     9481 tatacaccta tgtgttatga aaatggtgga gtagttgatg atttattaat atataaattt
     9541 ggtgaagaag attatttatt agtaataaat gcaggtaata tagataaaga tgtagcatgg
     9601 ataataaaac aaagtgaagg atacaatgta gatataaaaa atatatctag tgaagtgagt
     9661 caattagcaa ttcaaggacc taaagcagaa gaaattcttc aaaaaatcac agatatagac
     9721 ttaaactcaa taaaatttta taagtcaatt ccatcaacaa aagtatgtgg ttgtccttgt
     9781 ttagtttcaa gaacaggata tactggggaa gatgggtttg agatatactg taaaaataaa
     9841 tatgtagaaa taatttggaa tgaagttcta aaggttggag gagaagatat atgtccagct
     9901 ggtctaggtt gtagggatac tttgagattt gaagcagctc tacctctata tggacatgaa
     9961 ataaatgaac acatatctcc aattgaaggt ggtttatcta tctttgtgaa aacaaataaa
    10021 gaatcattta ttggcaaatc aattttatca aaagaaaaag aaagtggagc taaaagaaag
    10081 ttagtaggat ttgaaatgca aggtaaagga atgcctagaa atggatatga tataaggatt
    10141 ggtgataaaa cagttggatt tgtaacaaca ggatgtgcat ctccaacgac aggaaaaatt
    10201 ttaggtatgg gaattataga ttctgaatat gcaaaagtag gaaatgaaat aggtatagca
    10261 atcagaaaaa aagttgttcc tgctgtgata gttaagaaac ctttttataa aaaacaatat
    10321 aaaaaagata atattatatt aaacaaagaa aataaatttt catatatacc tgctacaagt
    10381 gaagataaat caaaaatgtt aaaagtagtt ggattaaatt cagttgatga attattttca
    10441 gatataccag aagaagtaaa attaaaaaga gatttaaatt tggaaattgg aaaatctgaa
    10501 ttagaggtaa gcaaaatagt aaaaagattg tcagaagaaa atttaagttt agaagacttg
    10561 acttgttttc ttggtgctgg tgcatatgac cattatatac catcaattat aaaacatata
    10621 acttcaagat ctgaatttta tacagcatat actccatatc aagctgaaat aagtcaggga
    10681 actttacaag tagtttttga atttcaatct atgattgcag aaattacagg tatggaaatt
    10741 gcaaatgcat caatgtatga tggagcaact gctgcaatag aagcatgtat aatggcaatg
    10801 aatcagacta gaaaaagtaa aatagtagtg tcaaaaacta ttcatcctga aactctgtca
    10861 gtattaagaa cttacttaca atataaagat tgtgagatag tagaaattga cttttgtaat
    10921 gaatatggga ctacagatat agaaaaatta aaagcttctg tagacaaaga tacagcatgt
    10981 gttcttatac aaactcctaa tttctttgga attattgaag aaatggaaga aatagaaaag
    11041 ataactcatg aaaataaggc tatgttaatt atgagtgtag acccaatatc attaggagtt
    11101 ttaaaaacac caggtgagat aggtgcagat attgttgttg gagaagctca atcacttgga
    11161 aaccctctta attttggagg tccttatgta ggatttttag ctagcaaatc taaatatact
    11221 agaaaaatgc caggaagaat agttgggcaa agtttagatg tagaaggtaa aattgcatat
    11281 gtattaactt tacaaactag agaacagcat gtaagaagag aaaaagcaac ttctaatata
    11341 tgttcaaatc aagctttaaa tgctcttgta gcttcaatat atatggctac tatgggtaaa
    11401 gaaggattta aagaggttgg tatgcagtct atgaaaaaag cacattatac ctacaataaa
    11461 cttgtacaaa ctggaaaata taagccaata tttaaaggta agtttttcaa agaatttgct
    11521 gtacaaggaa atcttaatat agaaactata aatgataaac tcttagaaga aaatatatta
    11581 ggaggttata atttagaata caattatcca gaattaaaaa attcaacttt gctttgtgtg
    11641 actgagaaaa gaagcaaaga ggaaatagat aagttagttg gaataatgga gggattataa
    11701 tgaaagaata caatagtttg ttgatagata tatctaaaaa aggtaggaaa gcatactcac
    11761 ttccaaagtt agatatagat gatataaaaa tagaagatat gattgaccca gatatggcaa
    11821 gacaaagtga gttgaatttg ccagaagttg gtgaattaga attagttaga cattatacat
    11881 tattatcaaa taaaaacttt ggagttgata caggttttta tcctttgggt tcttgtacta
    11941 tgaaatataa tcctaaaata aatgaagata tggcagcact tccaaacttt actggaatgc
    12001 atccatacca atcttcggat acagctcaag gttctctttc tttgatgtat gatttatcaa
    12061 gaagacttgc agaaattaca ggtatggatg aagttacact acaaccttca gcaggttctc
    12121 atggtgagtt tacagggctt atgattataa aagcatatca tgaaaataga ggtgaccata
    12181 agagaaccaa agtgataatt ccagattctg cacatggaac aaatccagca agtgcagcta
    12241 tggcaaactt tgatgtgatt caaatagcat ctgataaaaa tggagctgta gacataaatg
    12301 cattaaaaga ggttttgaat gatgaagtag cagctcttat gcttactaat ccaagtactc
    12361 ttggtttatt tgaaaaaaat ataaaagaaa tagctactct tgtacatgaa gcaggaggac
    12421 ttttgtacta tgatggtgca aacatgaacg ctattatggg gataacaaga cctggagata
    12481 tggggtttga tgtggttcat cttaatcttc ataagacttt ttcaactcct catggaggtg
    12541 gaggtccagg agctggtcct gttggagtta aaaaagaatt agtacctttt ttaccaatac
    12601 cagtaattga aagaaaagaa gataagtatg tactaaatta tgatagagaa aaatctattg
    12661 ggaaaattaa aaatttctat ggtaattttg gagttcttgt aagagcttac acatatatac
    12721 taactatggg aagggatgga cttaaagagg ctagtgaaat ggcagtttta aatgctaatt
    12781 atataaagga aagtataaaa gatgattata ttttgccaat agataccttg tgtaagcatg
    12841 agtttgtatt aggtggattg ccaagaggag aggccaatat aaaaactatc gatattgcaa
    12901 aaagactact agattatgga taccatcctc caacaatgta ctttcctctt attataaatg
    12961 aggcacttat gatagaacct acagaaagtg agagtataga gacattagat agttttatag
    13021 aagctatgaa aagtgttgct aaagaggcaa aggaagaacc agaactattg aaaactgctc
    13081 cacataatac tttggtcaaa agagtagatg atgcaagggc agtaaagaaa cctatactaa
    13141 catggtcaca aagataaata gttaaaaagt agagatttaa agtataaaga gaattaaatt
    13201 tgtaagaaaa agctatctaa cttaatctag tttagatagc ttttttgtat attagtatgt
    13261 atggtatttt ctatataaag ttttaaattg tattagtgct tatatagaat attgatatga
    13321 tgattatgta tagatattaa taagaattgt tgaatttatc ttgccttaac tttatttact
    13381 cttttatatt aagaaaaact taactaaaat atagcgaaat tcataaaaat ttaggaaatc
    13441 tt
//
LOCUS       DAEOTL010000098        13301 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEOTL010000098 DAEOTL010000000
VERSION     DAEOTL010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13301
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.099"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(60..2060)
                     /locus_tag="KRH82_003317"
     CDS             complement(60..2060)
                     /locus_tag="KRH82_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656578.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKNIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            complement(2091..3809)
                     /locus_tag="KRH82_003318"
     CDS             complement(2091..3809)
                     /locus_tag="KRH82_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBG8656579.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDSIRVAIANKKWNDDVTVTISAGVAHISDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            complement(4035..5273)
                     /gene="fabF"
                     /locus_tag="KRH82_003319"
     CDS             complement(4035..5273)
                     /gene="fabF"
                     /locus_tag="KRH82_003319"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBG8656580.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            complement(5302..5526)
                     /gene="acpP"
                     /locus_tag="KRH82_003320"
     CDS             complement(5302..5526)
                     /gene="acpP"
                     /locus_tag="KRH82_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBG8656581.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            complement(5580..6329)
                     /gene="fabG"
                     /locus_tag="KRH82_003321"
     CDS             complement(5580..6329)
                     /gene="fabG"
                     /locus_tag="KRH82_003321"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBG8656582.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            complement(6329..7279)
                     /gene="fabD"
                     /locus_tag="KRH82_003322"
     CDS             complement(6329..7279)
                     /gene="fabD"
                     /locus_tag="KRH82_003322"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBG8656583.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAVLGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            complement(7295..8224)
                     /gene="fabK"
                     /locus_tag="KRH82_003323"
     CDS             complement(7295..8224)
                     /gene="fabK"
                     /locus_tag="KRH82_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBG8656584.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            complement(8333..9319)
                     /locus_tag="KRH82_003324"
     CDS             complement(8333..9319)
                     /locus_tag="KRH82_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBG8656585.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            complement(9345..10367)
                     /gene="plsX"
                     /locus_tag="KRH82_003325"
     CDS             complement(9345..10367)
                     /gene="plsX"
                     /locus_tag="KRH82_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBG8656586.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            complement(10378..10935)
                     /gene="fapR"
                     /locus_tag="KRH82_003326"
     CDS             complement(10378..10935)
                     /gene="fapR"
                     /locus_tag="KRH82_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBG8656587.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            complement(11142..11318)
                     /gene="rpmF"
                     /locus_tag="KRH82_003327"
     CDS             complement(11142..11318)
                     /gene="rpmF"
                     /locus_tag="KRH82_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBG8656588.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            complement(11343..11867)
                     /locus_tag="KRH82_003328"
     CDS             complement(11343..11867)
                     /locus_tag="KRH82_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBG8656589.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            complement(11960..13156)
                     /locus_tag="KRH82_003329"
     CDS             complement(11960..13156)
                     /locus_tag="KRH82_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBG8656590.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
BASE COUNT         3910 a         2615 c         1386 g         5390 t
ORIGIN      
        1 tttattatta tttaaatatc taaattcaaa atatgtgatt tcaatatcaa atacttagct
       61 taatttatat tattataaag ttttatcccc tctgaggtta tttgacttcc tcctctacca
      121 gatttagatg atatgtatcc acattcactt aaataagata gcacctttct aactttgctt
      181 tcagaaatct caataccttc ctgtataagc ttttcgatta taaaccctct tccaattcca
      241 gaggatgact ctcttctttc atatagaatc ctcagtattt cctcaaattc ttttcttgta
      301 taaccaaatc catcttcata attgttagca cattctaccc ttatatatgg tggtaagtca
      361 tctctaaaaa ccatactatc acacattaga cttacataag aagcaacatt ttgtaactct
      421 cttatatttc ctggccaatt atatttttct aaaatagtta taacttctgg cgaaagtctt
      481 atattgtttt tcaaaaagaa attcataagt gttattatat cttcttttct attcctcaat
      541 gatggtacat ctattggcaa tacatttagt ctataataca ggtcctctct aaattttcct
      601 tctctaatca tctttagtaa gtttttgttt gttgctgcta tgaccctaac atctatgttt
      661 ataacattat gggaacctat aggcataacc tgcttttctt gtaataccct tagtaacttt
      721 gtctgtagca atggaggcat atctccaatt tcatccagaa atatagttcc attattagca
      781 agttcaaata gacccttttt tccttctctt aaagctcctg taaaagagcc tttttcatat
      841 ccaaacagtt gactttctaa tagactatct ggaactgctg cacaattaac tgctataaac
      901 ggttgattac ttctattgga agcattatga attgattgtg ataataattc tttaccagta
      961 ccactttctc ctattattaa tacagaaagg tctgatttag atattttttt agccaattct
     1021 acacacttta ccatattttt atttttagtt tttatatctt taaatgtata tcttgctatc
     1081 tgaccttgtt ctcttaattt attagtaaga ttttgttcta atttttttat atacgttatt
     1141 tcttgtaagt tataatatat cccagcttta ttccccatag aaaaaatatt ttttttattt
     1201 acatttatat attttttatt tgtaaatacc acttcatcaa ttatttcttt gtcttcaagt
     1261 aaaatattta aatcttcaga aatgatatct tctatgtttt tgccttgtgg attttcattt
     1321 atacctaaaa tttttaaagc ttctttatta aatgtgttta ttataccatc tgctgaagta
     1381 aatattattc catcttttga tagattcaat ataacatctt gttcttctat ttttaaaaac
     1441 agttgcctat aattatcttt aactccatta tctaaactta ttaaactctc agaatatgcc
     1501 attaaatttt tacgtatttc tttaacatct attctaagac catttattat ttctataaag
     1561 gtagatatat caatatatct atttccaagg tcgattactt tatttatata acttggtact
     1621 tttcccttta ctccaggcgt tatagctatg tctatatttt tataaatttt tccttcaata
     1681 tatggagtaa actttaaatt ttttactcct attttgtaaa ataagcttat cgtttctaag
     1741 gtagtttctt ttgtatcatt tacaaccaat acttcagttc catttggtat tgaaaataat
     1801 ccatatattt cattttcttt aagtgttctc cttatcacta taatcttact atcttgtact
     1861 aaatgctttc tcatactgtt taatctatcg tcattcatta ctagtacaaa atcaccttgt
     1921 attttatcat tctcttttaa aacttccaga taatagtggt ttatatcaat ataattacct
     1981 aaaaccaaac gtatattttc ttctaagaaa gatgatagtt tagttatttt atcagttact
     2041 atagctattg attgtttcat atttatacct cttatttata tagtatataa ttacttatat
     2101 actactttat ttctaccaag ttgttttgct ttatataaat ttttatcagc ttcttctagt
     2161 acatctttgc tatctgaaat atgagctaca cctgcactta tagtcacagt cacatcatca
     2221 ttccactttt tatttgcaat tgcaaccctt atactgtcaa ttatatctgc tacttcctca
     2281 ccagatttat ttcttattaa tacagaaaat tcttctcctc cgtacctaaa gactttatca
     2341 tcttgttcta acataacaca aatggtattt gttattccct ttataacagt gtcaccaaat
     2401 ttatgtccat aattatcatt tatgagcttg aaattatcaa tatctatcat cacaagtgca
     2461 aaattatcat ctttctctct gtacttttca tacataatat caaaactttt tctattataa
     2521 acatttgtaa gaccatcatg taaattttgt gctttaaaat acttcaatcg gttgtataaa
     2581 aaagtagacc ctaatatagc aattaaaatt acggtaaata atattttata atattttatt
     2641 tcttttttag ttttttcaaa tagcttactt tcgtttgata ctttatcaat tatatagaaa
     2701 ctagtctctg aatctcttat acttttgttc tctttatatt catttattaa catcttttga
     2761 tactcattta aagattctat atttccttgt ttttcatata tatttaatat cttatttaaa
     2821 ttttttattt tctcctgggt taactttctt ttggtagata tctctaaact ttttttataa
     2881 ttatctattg cagaattata attttcgctt ttatattcta agtttcccat tgccatataa
     2941 tagtacatat ctttatctaa tatataaact gttctatctg attttataag ataatcagct
     3001 ttttctaaaa aagtctttgc cttttgtata ttatttttgc ccacatacgc atttgactgc
     3061 attatagagg ccattatatc aaaatcattg taattatccg tatttacaaa ctttttataa
     3121 tcttttatcc tgctacttat ttcaatagct ttatcatatt ctccctcttc tacatatatt
     3181 tctgctagat ttataatagc atataatcta accattccat ttttttcacc ttcatcaata
     3241 tctattttaa aagaatcctt tattaatttc tctcctgttt catagccacc tatctttaaa
     3301 aatatgctcg ccaaatcaac atctagtctt gctttttcat aattattccc caatttctca
     3361 gccaacttta tagactttac agttaaatct actgccttag aataattatt atccattata
     3421 tacactgatg ctaatctttt ttctatatta aatctacatt catcagataa tttcacatct
     3481 gattctctca tcttttctaa agaatcaatg actatcttcg ttccatctgg aacatatgaa
     3541 atagtcttta acatatccca aacttcatta tatactttat tgtatttttt ttctggaata
     3601 gattcaaaag aagtcttaac cacttttttt gcttcatcat actccttatc tgccacaagg
     3661 ctttcagaca tatattttcc cttatttata atttctcttt ctttcaatcc attttggtca
     3721 tactttataa acaaaataat actaataagt attatacata taaaaattat ctttttgggt
     3781 aaccttttct ttggtagtct aaaattcaaa attttagtcc tccttttgta tattgtagaa
     3841 tgaaaacttg catatataaa taacctctta ataattaata atacaatata tcaaaatgat
     3901 ttacaacata tcctagactt aaatcttaat aaaaaagtct cctaaaataa tttaggagac
     3961 tttaaattta agctaatata aatttataca gttaaaacaa gtgcttgttt tttagtttta
     4021 tatttaatat ttatttatac atattttttt agtactattg tagcattatg cccaccaaat
     4081 cctaaagaat ttgatagtgc atatctaata tttttttctt taccttgatt tggaacataa
     4141 tctaaatcca aatcttcacc aacttcttgt atgtttatag ttggaggcac aaaactatct
     4201 tctatactca tagcacaaac aacagcctct atagcacctg atgctcctaa taagtgacca
     4261 gtcatagatt ttgttgatga cacacataag tcatatgcct tttctccaaa tacagttttt
     4321 atagccatag tttcatataa atcattgtaa taagttgaag ttccatgagc atttatataa
     4381 tctacttctt ctaatggaac atttccatct ttcaaagcca tattcataga cctagctgct
     4441 ccctctccat tttcagctgg agttgtcata tggtatgcat cagcagttaa accatatcca
     4501 actacttctg catatatttt agcgcctctt gctaaagcat gttctaagtc ttctaagata
     4561 acaatacctg ctccttctcc cattacaaaa ccatctctgt ctttatcaaa tggtcttgat
     4621 gcagttttag ggtcatcatt tctagttgac atagccttca tgttacagaa tccagcaaaa
     4681 gcaagacctg ttacagcagc ttcagaaccc cctgctacca taatgtctgc atcacctctt
     4741 tgaattacct taaaagcatc acctattgaa tgagttcctg atgcacaagc tgtacataca
     4801 ttagtgttag gcccttttgc tcctaaaaat attgaaactt gaccagctgc catatttcct
     4861 atcatcatag gtacaaaaag tgaacttact cttttatttc ctttttccaa aagaatttta
     4921 tgttgagttt ctatggcttc aactccacct attccagaac ctattataac accaaaacgt
     4981 tctctatcaa ctttatctaa atcaagattt gcatcttcaa ctgctaattt agcagatact
     5041 attgcaaatt gagcaaattt atctaatctc ttcaattctt ttttacttat atattcttct
     5101 ggatgaaaat tcttaacttc tcctgctatc tgagtttgat atgtgctagc atcaaaatta
     5161 gttattttat ctataccaga tactccagat tttatattac tccagaactc ttcttttcct
     5221 gttcccaacg gcgtaacaca tccaagtcct gttattacta ctcttttatt catcggatac
     5281 ctccactttt ttaaagctcg actatttatt agcttctata tacttaacta tatctcctat
     5341 agatttgaag ttttctgctt ctgtatctgg tatttctata ccaaattcat cttcaagtgc
     5401 cattattatt tctactgcat ctaatgaatc tgcttctaaa tccttcatta atgatgtttc
     5461 catagttatt tctttatctt ctactcctaa ttgctctatt attatttcta caactttatt
     5521 aaacattgtg tacctcctaa aattttttat tttaatagat ttctctactt tttaaattat
     5581 tattgcatta ccattccacc atctacattt attacttgtc ctgttatata acttgacatg
     5641 tcactaacta aaaatgctac ggcattggct acatcttctg gtttaccata agatttcttt
     5701 ggtatgtttg ctagtgttga ttcttttaca tcatcactta gtactttagt catatctgtt
     5761 tctataaatc caggtgctac tgcatttata tttatgtttc ttgatgctaa ctctcttgca
     5821 gaagcttttg taaatccaat tacacctgct tttgatgcac aataattagt ttgccctgca
     5881 ttacccataa ttccaactac tgaagtcata tttattattc ttccatactt ctttttcatc
     5941 ataggtttag taactgcttt tgtacaatta aagacacctt ttaagtttat atctataact
     6001 ctatcaaaat cttcttcttt cattctcata agcagaccat ctttagttat gcctgcatta
     6061 ttaaccaata tatcaatttt tccaaattcg cttacaacag aatctatcat ttgattcact
     6121 tcatcaaatt tagatacatc acattttata gaggtacact ttacccccat actttctatt
     6181 tcatttttag tttttagtgc ttcatcttct ttagaagtat aattgattac tacatcagct
     6241 ccaaaagatg ctagtttttt tgctatttct tttcctatac ccctagagcc accagtaaca
     6301 actgctactt gtcctgtaag atttatcatt atatctctcc atttctataa ttttgtacaa
     6361 attcattaag agaatctata ccatctatat tataaatatt gacatttgct tttttattgg
     6421 aagctatctt cttaataaat gcttttaaag tttttccagg tcccatttct ataaaagtat
     6481 catatccatc atttaaaagt ctttctatag aatcttccca aagaacagat gaacttactt
     6541 gttttataag caggtcttta ccttcgtttt tatagtaatc tgcatttaca tttgccacca
     6601 catcaacttt aggtttagtt atgttaactt tttctaattc actggccaat tttacaccag
     6661 cttcttttaa cattgatgag tgaaaaggtc cacttacatt taatttaact gccctttttg
     6721 ctcctgcttc tttgcatttt accattgctt cttctatctt ttcattttca ccagatataa
     6781 ctatttgtcc aggagaattg taatttgcta cttctacaat acctccttgt atatctttaa
     6841 ccacattttc aagtacattt ctatctaaac ctaaaactgc tgccatagct ccaacacctg
     6901 ctggaactgt ttcctgcata aacttacctc tttttttaac taaacataca gcatctttaa
     6961 agtcaattgc atctgctgca accaacgcac tatactctcc taaggataat cctaagcatg
     7021 cattatattt taaatctatt tgagcttgta ccgcttttaa tactgctaca ctatgtgtaa
     7081 ccatggcagg ttgagtgttt tcagttttag aaagttcttc ttcatttcca ttaaacataa
     7141 ggttttttaa atccatattt aaggcatcac tagcctcatc tattacactt ttagcaacag
     7201 cattattttc atataaatcc ttggccatac ctacatattg agctccttga ccagggaata
     7261 ctagtgcaac ttttcccatc ttgctcctcc tgatttacag ttctattgct ggcataatct
     7321 ctcttgcttg atttaccata gcctctataa tttccttaca aggtgttatt tcttttacca
     7381 tagcagcact ttgacctgcc ataaatgaac ctttttctat gtctccatct actgttgcaa
     7441 atcttaaagc tcctgtacct tttttatcca gttcttcagg agtagctcca ttttgttcca
     7501 tctttaaaaa ttcttttgat agtttatttt ttaatgttct tactggatga ccagtacttc
     7561 ttcctgttac aattgcatct ctatcttttg cttttagtac taagttttta tagtttgaat
     7621 ggacagaaca ctcttcactg caaataaatc tagttcctac ttgaactgca ctggcaccta
     7681 atgcaaatga tgctgcaatt cctctaccat ctacaattcc tccagcagct attacaggta
     7741 tgtttacagc atcagcaact tgtggaacta agaccatagt agtaagttct cctatatgtc
     7801 ctccaccttc agtaccttct gctattactg ctgtagctcc tagcttttcc attctttgtg
     7861 ccaaagctat tgtaggtact acaggaataa cctttgttcc agcttccttt aatctatcca
     7921 tatactttgc aggatttcca gcaccagtag taataacttg aactttttct tctataatca
     7981 aatcaattat atcatcaaca aatggcgaca taagcattac atttactcca aaaggtttat
     8041 ctgttaattt tttacactca acaatttctt tctttatagc ttcttttggt gcgtttcctg
     8101 ctgctattat gccaagtcct cctgcattag atacagcact tgctaatgat gcagtagcta
     8161 cccatgccat tcccccttgg ataactgggt attttatatt taatattttg caaattttat
     8221 tcatacaatt ctccttcatt tgaaatcata aaagtaaact ttttattatt aatcaacttt
     8281 attttgtgta taagtttaat tttgttaatt aaatcatttt agatatttta tactataaag
     8341 tccacttgac aactgaagcc ccccaagtta gacctccacc aaagccaact aaaactacat
     8401 tatcaccctt tttaatttta ccttctctat aagcttcatc taatgctact ggtatagatg
     8461 cagcagacat atttccatat ttgtctatat ttacataaac ttttttcata tcaagctcta
     8521 atctcttaga agaagcttgt atgattctta tattagcttg atgtggcact aagtagtcta
     8581 tatcagttgt atttagattt gctttttcaa gagctcttaa agaagtttct gccatctttc
     8641 taactgcaaa tttaaacaca tcactacctg ccatttctat tgtatgtaga ttagcttcta
     8701 cagtctcttt acttgcctta agtcttgaac ctccagcagg tacttttaaa caatcttttc
     8761 ctttaccatc agagcccata tgtgtagaca gtattccacc ctcatttaca gggccaataa
     8821 cagctgctcc agctccatct ccaaacaata ctgctgttgt tctatcatca taatttaaaa
     8881 acttagaaca agtttctgct cctattacaa gcacattttt atagcaacct gtttccacaa
     8941 attgctttgc aatagttact ccatatacaa atccagaaca agctgctgat atatcaaatg
     9001 cagtagcatt cactgctcct attgcatctt gtactataca tgcagttgaa ggcaaagaca
     9061 tatcaggagt aattgtagct aatataatca gctctatatc ctctacgttt aactttgcac
     9121 attctatagc ttttaaggca gctttagatg ctaagtcaga agttgcttca gactctttgg
     9181 caaatcttct ttccttaata ccagttctag tacttatcca ctcatctgat gtatccatta
     9241 ttttttcgaa gtgaaaatta tcatatgatt gctcaggtag ataacttcct actcctaata
     9301 ttccagcctt tgtattcatt atatattaaa cctccaaaac gagtttattc atcttcgtta
     9361 tttttatttt cttcattgta tttgcttata aattggttaa tatcttcaac gacttttccc
     9421 tttgaaaatt ttattccttg atttatagca ttttttatag ctttagcatc agaactacca
     9481 tgagctttta taactcctcc atttagacct aaaagtggag ctcccccata ctcagaataa
     9541 tctataaaac tttttaattt tcttaaatca tcctttataa gtaatgctcc tattttactt
     9601 tttgtactgg ccataaaagt ttcctttata agactcataa ctgaaagtgc tacaccttca
     9661 gcagatttaa gtaatatatt acctgtaaat ccatcacata tgattatatc tgtgtatgca
     9721 tttataactt ctctagcttc tacattccct ataaaattta aatctaattt tttaatttct
     9781 tcatatgacc ttttgactaa atcattgcct ttgccttctt ctagtccaac atttgctaat
     9841 gctaccttag gattttcaag acctaaaact tttcttgaat aaatattact catagctgca
     9901 aattcaacta gattcttagg tttacaatct gcatttgcgc cacagtctgc tataagtgtc
     9961 attcctcgct ttacatttgg tattgctgaa cataagcaag gtctatcgat tccttttatt
    10021 ctaccaacaa caaataatcc accagcaagt aaggctcctg tatttccagc tgatattata
    10081 gcatctgcct ttccttcttt tacaagattt aatgctacta ccatagatga atctttttta
    10141 cttcttatag cctttactgg tttatcttcg ttttctataa tctcagtagt atgaactatc
    10201 tctaatttat ttctatcaaa ttcataattt gaaaattcct tttcaagtaa atctttatct
    10261 cctgtgatta ttaaatcaac ctgatattct tttatagcat ttactgcgcc ttctacatta
    10321 gatttaggtg cattatctcc acccattcca tcaattacta ttttcataat ttccctccta
    10381 atctaattct tcaaagataa actttcctct aaatatttgc tcttgggctt tattgttgat
    10441 aacaactttt acataatgct ttttatctat atttctatac acttctgctt ttgctataag
    10501 tctatcttgt tgttctatca acttaaaact ttttacattt gcaactctca taataacctt
    10561 aggtgcatct attatagcca ttgccaatga atctgctaga gaaaaaatat acgtatcttt
    10621 taaagtatta gtcttagagt aaatcatgtc ctgtgtaact tctaacatag atatacctaa
    10681 tcgccctaca gataaatcaa tgatttctcc tgtaatttcc tttactccta aagtctttac
    10741 ttttgaactc tgagtttctg ctattgattt gactctttct cttagctctg gtatgtttag
    10801 actcattcta tctaatctta tggtctgtat acttacatca aacagacttg ataattcttc
    10861 atcagtataa aaaggatctg tctttagcat atctataagc tctttttgtc tttgggcttt
    10921 acttttcttt ttcatgttcc ctccaaattt tatagctgta attagtacca gctactaata
    10981 gtagtatata gtaacacaca aaaattttca atacttatat tattattttt ctatttttta
    11041 atatgcataa aatccactta ttttctctag taaatcatct tattttttta tatgtacaaa
    11101 aaaaacatgt agagtatact ctacatgctt tttagaagct attacttaga cacaacttct
    11161 ttacctttat aatatccaca gtctggacac actctatgtg gtaattttgg ctcatgacat
    11221 tgtgggcaac ttacaaatcc tgttgcttcc atctttgagt tagctgctct tctcattttt
    11281 gtgtttgatt tagacgtttt acgctttggt actgccattt acgccacctc cttagtcaaa
    11341 atttaattaa ataaatcttt taatttagca aaacgaggat ctatgtattc ctcatcgttt
    11401 gtaatttcac tgcaagaaca ctcttcttca tttaagtttg ccccgcatac ttgacaaaga
    11461 cctttacagt tttcactaca aagaacttta tgaggtacat taaaatctaa tgtctgttct
    11521 attatatcaa taaggtcgat ttcttcacca tcgaatataa aaggatcaaa ttcctcaaac
    11581 tcatcttcat cataatcttc ttcttttact aaaaaacctt gtatagaata ctctagtggt
    11641 atttctactt ctttaagaca tcttgaacaa ttgtcaacaa ttgtaaaatt gacatctata
    11701 tctagataca aacctttatt agtctttgac actttccctt ttaaatttac aggtgatact
    11761 aatttgtaaa tctcatcaca ataactaata gtatcaattt tttcacaaaa attcaagtct
    11821 attttgtcag tttcttttct atttattttt tctatgctaa ctttcattaa gttcacctca
    11881 acatatcacc aaatttatta tacaaatcta gcatttgttt gtcaagtatt tttacttgat
    11941 aggcataggt ttaatttaat tattttacca atcttaatgt atctctagct atcattaatt
    12001 cttcattagt tggtattaaa agcattttta ctttagaatc agcagtagat attactgttt
    12061 cttttcctct aacatcatta gcttctttat ctaatttcat tcctaaaaac tccatgttag
    12121 aagcaatatc tgctcttata gcctttccat tttcaccaac gcctgcagta aatactacaa
    12181 catccaatcc attcatttca gcagcataag cgcctatata tttttgtact tttttaacat
    12241 acgcttctaa tgtagcttga gctctttcgt ctccattttt agctgcatct tctatatctc
    12301 tgaagtcact agaaattcca gtcattccat atactccaga ttctttattc attaatttat
    12361 ccaatccatc agcatctaaa ccttcttttc tcattaagaa tggtaatata gctgggtcta
    12421 tatctccaca tctagttccc attattaatc cttctaatgg agtgaatccc atagatgtat
    12481 ctacacattt tccaccatca acagcagcta tagaagcacc atttcctaag tgacaagtta
    12541 ctatttttaa atcttttata tcttttccta gtatctctgc tgctctttga gatacataat
    12601 tatgagaagt tccgtggaat ccatatcttc ttaccccata tttagtatat agctcatgag
    12661 gtaaaccata taagtatgaa gatttaggca ttgtttgatg gaaagcagta tcaaatacac
    12721 ctaccattgg tacatctgga agtatagctt tacaagcatc tattcccatt atgtttgctg
    12781 gattatgaag tggagctaaa tctatacatt cttttaaagc ttcttctact tctggagtta
    12841 ttactactga agttgcaaat ttttctccag catgtacaac tctatgtcct actgcatcta
    12901 tttctttcat ttctttaact gcaccaaatt ctggatgagc aacagcttct aaaactaatg
    12961 ctattgcatc tttgtggtcc ttcattggtt gttcaacaac gtatttatca tctctacctg
    13021 ctttttcatg ttttaatata gaaccttcta ttcctattct ttcaaccaat cctatacata
    13081 aaacttcttc attattcata tctattaatt gatattttaa tgaagaactc ccacagttta
    13141 atactaatat tttcattatt atttcctcct tagatttttt tataaataat atgtaataaa
    13201 ttttgatttg taataaatgt ctaaataaaa ctctatcttt tattattttg ttatagatat
    13261 gttattgtat acattaaacg attttcataa ataatatatc a
//
LOCUS       DAEOTL010000099        13296 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEOTL010000099 DAEOTL010000000
VERSION     DAEOTL010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.100"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(146..799)
                     /locus_tag="KRH82_003330"
     CDS             complement(146..799)
                     /locus_tag="KRH82_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656591.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPMEEMKKEKLL"
     gene            complement(1044..2909)
                     /locus_tag="KRH82_003331"
     CDS             complement(1044..2909)
                     /locus_tag="KRH82_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBG8656592.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDS
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(2914..5334)
                     /locus_tag="KRH82_003332"
     CDS             complement(2914..5334)
                     /locus_tag="KRH82_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBG8656593.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMIKELLPRIYMIIEEINRRYVE
                     ELNNKGYEQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(5348..6790)
                     /gene="glgA"
                     /locus_tag="KRH82_003333"
     CDS             complement(5348..6790)
                     /gene="glgA"
                     /locus_tag="KRH82_003333"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBG8656594.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSID
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(6819..7949)
                     /gene="glgD"
                     /locus_tag="KRH82_003334"
     CDS             complement(6819..7949)
                     /gene="glgD"
                     /locus_tag="KRH82_003334"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBG8656595.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(7951..9111)
                     /locus_tag="KRH82_003335"
     CDS             complement(7951..9111)
                     /locus_tag="KRH82_003335"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBG8656596.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(9882..10925)
                     /locus_tag="KRH82_003336"
     CDS             complement(9882..10925)
                     /locus_tag="KRH82_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBG8656597.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(10946..11392)
                     /locus_tag="KRH82_003337"
     CDS             complement(10946..11392)
                     /locus_tag="KRH82_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBG8656598.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(11566..13146)
                     /locus_tag="KRH82_003338"
     CDS             complement(11566..13146)
                     /locus_tag="KRH82_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBG8656599.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
BASE COUNT         4222 a         2430 c         1268 g         5376 t
ORIGIN      
        1 ttgatttata tatgttaatt taaatacatt attctatcgt agtgccttag agtttttatt
       61 tgtatttaaa gttaaattta ttcttgtttt tcctttaata tttaatagta aaacaacaaa
      121 attataaaaa aaataaagag aaactttata aaagcttctc ttttttcatc tcttccatag
      181 gtatcgtttt ccaatgttct ctcaaaactc tttcaacatt ttctaaatca ttctccctca
      241 tagattttac tacttcaata tgttgattat tgctgtatgt caacatttta tataactcat
      301 cttcattatc actagtatat gactttgaca taaaattata tcttaaagag ttcaatagat
      361 ttactaacac ctgattatct gatttagtta tgtatatatc gtgaaattca ttacttaatt
      421 ttaaatagct attgtaattt ttatacttta tagagaccgc catcatttcc gttaattctt
      481 ccatttttac taggtctgat tcagttaaat tttgtaatgc tgaagaaccg gctaacgcat
      541 ccaatactcc aattacggaa taggtgtcta atttctcctt ttcctgaaat tcttttacta
      601 caaatccctt attaggtatt ttttctagta aattttcacc tgctaaccta gttaatgctt
      661 ctctcgctgg tgttctacta actccgatag atttacaaat ctcagattca gtaattctct
      721 gattagcttc atattctcca ttttggattt tctttgatat atagtcatat acttgagttg
      781 taagtggatc taccttcata agacgttcct ccatattaag attataaaag ttaaatctcc
      841 ctacaacttt ggtagagagt tcagttttat cttactaatt tatataatat cacaattatg
      901 atatttttta tacttctttg taatattttg aaatactaaa attcttatga taatttatac
      961 aaaaaaagta gaaaaagttt tgataaaaca aaactctttc cacattcacc ttattttcta
     1021 tttatttttc taaaaaaaga tatttaattt actctaaaaa ttctaaatga tttagagtct
     1081 aaatctactt tcaactcatt attttcaatt tgtatagtac tatttgcatt tttaagacta
     1141 tactttatag gtatttcctc aataaaacta ctctctatac ataatgatat actttccaca
     1201 ttttcacttc tatttactaa aattaacatt ctatcattat tttcattaac tctaataaaa
     1261 gaaaatacag aatcattatt agtatatata aattctgtat ttccagaact taaaagttta
     1321 ttcttatttc taatttttat aacatctcta taaaaattaa gcatatcttc gtcttcattt
     1381 ttccatggat aagttcttct attatctggg tcaacacctc cacaaagacc tgcttcatct
     1441 ccataatata tatatggtac tccttcaaat gtcatctgta tagctacagc aagcttcact
     1501 aaatctacat catcatttaa ttccgtttta gctcttgtaa catcatgtgt tccaattaaa
     1561 tttaaattag acctaaatga ttcttttgga taattttctt taatctgcat atatctatta
     1621 caaagttcat atgaattaat ttctcctttt aagaaagaaa acatgttatt tctaaaagga
     1681 taacccataa cagaatctaa ttcttcacct aataaataac ttcttctctg accatagcta
     1741 atcttatttg atgcatcttc ccatacttca cctataagaa ttgagtcatc atctgccttt
     1801 tttaattcct tttttaactc tcttataaac ttagttggta attcgtctgc aacatctagt
     1861 ctccagccct taatacccat atttacccat ttatttataa cgctatcatt gtcatatatt
     1921 atataatcca tatagctatg ttctaattca tttatatttg gcaatgtctt aacatcccac
     1981 caacttttat atttttgagg aaattcttca aacatatacc atgaataata tggagattct
     2041 ttagattgat atgcccctaa actattatag tttccataca tattaaaata tttactatct
     2101 gctccagtat gactaaaaac tccatctaat actattgata tacctttttc ttttgcttta
     2161 tcaataagtt ctttaaatgt atcttcatcc ccaaacattg ggtcaatttt tttatagtca
     2221 cctgtatcat acttatgatt actagaggct tcaaatatag ggcttagata tagtatactt
     2281 acacctaatt tttttaaata tccaagttta ttgattatcc ctcttaaatt tccaccatgg
     2341 aaatcccatc ttataacatc cccttgacta tcctttatgt acataggtgt atcttcccaa
     2401 tttccatata tgaaactatt ttttttagga ctatcaacct taccactacg atttccatta
     2461 ttgaatctat ctacaaatat atgataaagt attccttctt tgtaccatgt tggtacttta
     2521 aaatctttat aaacagtgat ttgatattta ttaatatcac tataattata ttcacaagaa
     2581 tatccattat ctctgttttt tccataaaat aaagtcttta tctgaccatc catttcaaca
     2641 tcaactttaa agtaataaaa ataaacacct gtaccatcaa acttttcaat cttaccacaa
     2701 aagcactttc caagtttatc attatctaat tcttcattta aagttattgt tctcatttct
     2761 tcttctctat ttatttctag ggaaatagac ttgatattgt atccctcatt tactttaaca
     2821 caaatggtca attcctcatc aaattttaaa gctccaaacg gagccttaaa atttttatcc
     2881 caagagttat attctattac actttgcatt taatcacacc cttttaaacc aaatgtcttt
     2941 tgcatactca gaaattgttc tatcagaaga aaaaaatcca gagttagcta tattaactaa
     3001 agacatttta ttccattttt ctttatctct atataacctg tttatatctg cttgagcttg
     3061 accataattt tcaaaatctc tcaatacaaa atactcatca ttgtaagtag tgagtgaatt
     3121 ataaatactt cttccttctt cgccaagatt aggaataaat ccatttatta aatcatctac
     3181 tacccttttt atatccatat tagaatgata taggtcaagt gaagaatatc caccatattt
     3241 attataattt agtacttgtt ctgcactaag tccaaataaa aacatatttt ctttaccaac
     3301 ctgttcacat atctctacat ttgcaccgtc aagtgtagcc aaagttatag caccattcat
     3361 cataaacttc atattacttg ttccagatgc ttccttagtt gtagttgaaa tttgctcact
     3421 aacatttgct gctggtatta ttatttctgc taatgatact ccataattct ctaaaaatac
     3481 tacttttaac ttgtccttta ctctaacatc attatttata gtacttgcaa cagaatttat
     3541 aaatttaatt atacatttag ccaaataata tcctggtgct gcttttgcgc caaatataaa
     3601 agttcttggg tcaagattca aattaggatt atcaagtaat tcatgataca tatgaagtac
     3661 attaaatata ttcagtaact gtcttttata cgcatgcaat ctcttaactt gaacatcaaa
     3721 tatcgaactt gggtctacat ttaaatcgta tttatctttt ataaactttg ctagatttgc
     3781 tttattattg tattttatat catcaagtct ttgtaaaaca gaggaatcat ttttaaattt
     3841 ttcaatattt tttaattgta atgtatcttt cttccatgaa tcaccaatta aatctgtaat
     3901 taaattgcta agttgaggat ttgaacttat aagccatcgc ctatgtgcaa ttccattagt
     3961 cttattatta aatttatttg gttcatcttg atagaaatct tttaatacct ctgtttcaag
     4021 aatatgagta tgaagcttag caactccatt tacactatga cttgtgacaa tacataagtt
     4081 tgccatattg atattgtcac agtctattat actcattctt tttattctat cctgctcata
     4141 tcctttatta tttaattcct ctacatatct tctatttatt tcttctatta tcatataaat
     4201 tcttggtaat agttctttaa tcatacttac aggccatttt tccattgctt ctgacattat
     4261 agtatgatta gtataggaca ctgttttttt agttatttcc catgcttcat cccaagataa
     4321 attttcttca tcaagcaaaa ttctcataag ttctggtatg cataaggtag gatgtgtatc
     4381 atttatatga attgctacct tatcgaataa attattaata tttaatttgt tctttttata
     4441 ttttcttatt atatcttgta tccctgcact tacaaaaaag tattcttgtt tcaacctcaa
     4501 caacttacct gcataatttg aatcatcagg atataatacc tgtgatattt cctcagtata
     4561 atacttatgt tttaaagcct cttcatagct accagaataa tttagagcat ttgaagtaag
     4621 ttcaccaaaa tctctctttg gtatttcact cttaaacaat cttaaagtat ttatacattg
     4681 gttttggtat ccgattattg gtatatcata aggcattgcc attacaggaa ggtagttttt
     4741 atgaattact tttaaatgac taccttcctt gattaattct acctcaccac caaacttcac
     4801 cattgttgct tcatttggtc ttacagtttc ccatgcatat cgtccttctg taagccagtt
     4861 atcaggcact tctacctgat aaccatttac aaatttttgt tcaaacagac catatttata
     4921 ccttattcca tatccttgac cacttatgtt caaagatgcc atagaatcta aaaagcaagc
     4981 tgctaatcta ccaagtccac catttcctaa ggctgggtct acttcagctt caattaaatc
     5041 atccaagttg attcctaatt cagatagacc ttctctaact tcttcttcaa tatttaaatt
     5101 taataaatta gattttaact gtctccctat taaaaattct aaactaaaat aataaacttc
     5161 ttttttctta tctaactttg tagcaaccca tttttttgct atctcatctt tcaatagact
     5221 acataataca tttaacaatt gttcatcagt agcttccttg atagattgtg catataagct
     5281 atacattttt acttcaaatt tttgcttgaa tttctttttg cttattgtta ccaaaaaaac
     5341 cactccttta atcacatatg tctctatatg tttctatata ctccttagct gattttttcc
     5401 aactattatc tgttttcatt gcattttcaa ctaatttaat ccatttttct ttgtccttaa
     5461 atactttgat tgcatttttc aaacagaaaa acatctcatg agcattgtaa tttttaaaac
     5521 taaatccatt gccttctcca gtaaatttat tataaggtgt tactgtatct ctaagccctc
     5581 cagtctctct aactattggt aaagaaccat atctcatagc taacatttga cctataccac
     5641 aaggctcaaa taatgatggc attaagaaca tatcacttgc agcatatatc tgttgagcca
     5701 atgatgcatt aaaagtaatt ctagctgata ctttatctga aaaattagaa tcgtaatagt
     5761 tgaacattga ttgatattga tgttctccag ttcctaaaac gacaatctgt aaatcttctc
     5821 tcataagttc tggcatcatg tatgctatta aatcaaatcc tttttgagaa actaatctcg
     5881 aaactatacc tatcaacgga atagatgaat ctttttttag tcccaatata tcttgtaatc
     5941 tcaatttatt ttctactttt ttgtcaattg agtctacatc ataatgaaca aatatatctt
     6001 tatcttttgc agggtcattt aaatcataat ctataccatt taatatacct tttaattttc
     6061 ctgactcttt tctaagtaat ccatctaatt gttcgccata aaaagatgtt tgtatttcat
     6121 ttgcataagt agggctaaca gttataattt tatctgcaaa atttatacca gctttcataa
     6181 aatttattga gccataatac tctatatctc cattatcaaa gtatttttgt ggtaaatcca
     6241 atatatcata taaaacatgc ttatcaaata caccttgata ttggagatta tgtatagtat
     6301 acatagtttt tatattttta tacccctcaa gggttgcata tctttctttt agaattaatg
     6361 gtaacatccc tgtatgccaa tcatttatat gtattacatc tggataaaaa tcaattctac
     6421 ttatagcttc taaaactgca tctgtaaaga aagtatatct ttctgcatca tctccatatc
     6481 catagatact ctttctttca tcttctcttc taaaataaaa ttcattatct ataaagtaaa
     6541 attttacacc atctaattcc atttctaaaa gaccacagta ttgatttctc catccaacac
     6601 gtacactaaa cacagctatt tcttttagtt gatcttttaa ataacttggt atagttgaat
     6661 atttgggcat tattaccctt acatctacac cttctttttt taattcttta ggcaatgcat
     6721 aagaaacatc tcctaatcct ccagtttttg caaagggcca acactctgct gttacataaa
     6781 aaaccttcat tagtcattcc cccttctaaa aaatttattt atatatttgt attcttttcc
     6841 actacaagag gatatttttc atctcctctt aattctttcc catttgatac actcgtattt
     6901 ttatctaata ttgcattata tagttttgca tttgacttta ttacacaatt ttgcattact
     6961 attgagttct ctataactgt tcctttttca acatttacct ttctaaatat gatactatct
     7021 tttacagtac cttctattaa acaaccagat gctataaagc tattttctac tttagcacta
     7081 tctgtataaa ttgtaggtga ttcattcttt tcttttgtaa atatctttct ttcagaatat
     7141 aataattcat ctgcaacttc taaatttaat aaatctttgc tcatttcaaa atatgattca
     7201 acagaattta cacattttag atatcctgta tattcatagg ctcctatttt catgttttct
     7261 gcttcttcaa taataaattc ttctaaataa caataattgc ctttatttac aatgttatat
     7321 atacattcaa caaaatcttc acgcttcata atatatgtct ccatacatat gtttgctcta
     7381 gggaacttac ctaaattatt tcctacattt attaccctat tgttactatc taaatttaga
     7441 gttaagttac cagcaaaatc tttatttgca ttatttacat ttttatatat tatagttata
     7501 tcattatgag attttttatg gtattccaat gcttgagaat aatttaaatt gcatagcata
     7561 tagcttggag ctattaaaat atattcttct tcactctttt ctatataatc tagattagct
     7621 aagatagtat atatatcacc ttctctatgt gagtaagtat ttctatactt agtgttttct
     7681 ggactaaaaa ttgataggcc accttttttt ctacttaaat cccaatcttt accactacct
     7741 atatggtctg ttaatgatct gtatttttct tttgcgaata ttccaacttt agtgattcct
     7801 gaatttatca tattagataa agcaaagtct attattctat atcttccagc tattggtgta
     7861 gatgctattg gtcttccata gttaagtttg tttattgctg ggtctccttt tttgtttaaa
     7921 tttattatcc ctaaacattc atttctcatc ttaaagacct ccttctatta atacgcatct
     7981 aggttcgata ttttcatact cagaaactac atttatttca ttatttacat tctttatctg
     8041 aacattatca tttatagttg cacactcacc tatcatagct ttttctatag ttacattttc
     8101 acctattaca acatttggca ttattactga atcaattact ttacttcctt ttccaacaac
     8161 aactccatgt gataatacag agttacctac ttcacctaaa attctacaac catcagctat
     8221 cattgatcta tgaacatttg catttttacc tatatattgt ggaggcattg ccatagtatt
     8281 tgtatatatc ttccatttag ggtctgctaa atcaagtgtt tctggagatt ttattatatc
     8341 catattagca tcccatagac tttgtatagt tcctacatct ctccagtatc ctttaaatgg
     8401 ataagcatac attccaacat tatcttctaa cattttaggt attaaatttt ttccaaaatc
     8461 atcataattt atttctggat ttttttctgc ttccttaaaa taatttctca acattttcca
     8521 atcaaatatg tatactccca tagatgccaa attgctctta ggttcacttg gtttttcttc
     8581 aaattcatag atacttgaat cttcatttgt attcattatc ccaaatcttg aagcttcatc
     8641 ccaaggaact tcaatcactg ctattgtagc tttagagcct ttttccttat gaaattttaa
     8701 cattttgcta taatccatct tgtatatatg gtcaccagat aatatcaata catattctgg
     8761 attataggta tctacaaagt ccatattttg atatatcgca tgtgctgtac cattatacca
     8821 atttccttct ttttcattca taaatggttg taaaacatag acaccaccat ttattctgtc
     8881 caaatcccaa tgacttccca ttcctatatg tgaatttaat atcaacggtc tatattgagt
     8941 taaaacacct acagtatcaa taccagagtt tgaacaattg cttaacacaa aatctataat
     9001 tctatactta cctccaaatg atacagctgg tttggcaatt ctttttgtaa aaacacctaa
     9061 tcttgaacct tgccctcctg ccaaaatcat agctaacatc tcttttttca tttaatgaca
     9121 ctcccctcat ctagtaatta atatttataa ttgcattttt acttttataa actttatcag
     9181 tcaataaatg tcgtgtataa atgttgctta aataatacct taataaaaat aaaataatat
     9241 caactataca attgatataa tgtatacccc ataatgaact taccgacgta tacattattt
     9301 tccataagca ctatagtatt tattaatatt caattatcgg ttaaaaaata atacaaattt
     9361 tattttataa atataaaaac attttttata aatctcttgt gtcatatgaa catgcttatt
     9421 ttttaatttg ttaaattcgt aatagcaaaa tataatctaa tatttgttaa ataattatcc
     9481 aaggaaaatc aagtaattat taatcaactt tattttttaa ttgatacttc tttgtctata
     9541 atttaaacaa aaggatataa acttttaaat tatttattag ttttcttagt attaatgttt
     9601 atatttttat aaatatatat taataatata aatagactaa ctaaaaccat gcttatttgc
     9661 tatatgtttt atataatatt atataacact ttttacatta gtaaaggata aattgtataa
     9721 agattctgtt aatttatttt tataatttca tctttctaat aaaaacaaag aagaagactt
     9781 aaaaatttat aagtcctctt cttttcaacg tgcatttttg tgctatattt aattaattcg
     9841 acctttaatt tccatatcct tcctatgata acaaaactct tttatttttt taatgattca
     9901 ttatcattta aaacttcttt tatatcaagt acttctttgt tatcatcact cataacttcc
     9961 tttattcctt tgaatgttcc taggaaatta actgcttctg aaggtaaaac cagttttgtt
    10021 gacttacctt cagccatttt ttcaagagct tccatagatt ttaatgctag aatattattg
    10081 tctatatcag cctctttcat tgctgaaaaa actaatttta aaccttctgc tgttgccatt
    10141 tgagttcttt ttatcatttc agcttcacct tgtgccttag caatagctgt ctgtcttata
    10201 gcttcagctt caccttctgc cactaatata gcagattctt tttcaccttc tgctacacgt
    10261 accatagctt cttttttggc ttctgctgtt aatatagcag attgtttttc accttcagct
    10321 tgaagtattg cagctgactt attaccttct gcttgaagta ttgcctctct tctttctctt
    10381 tctgctctca tttgtttttc cattgcaact tgaatatcct gaggaggcat tatatttttt
    10441 aactctactc tatttacttt tataccccat ttatctgttg cttcatcaag gatagttctc
    10501 atttttacat ttattatatc tcttgatgtt aatgtttcat ctaaatcaag ttcaccaatt
    10561 atatttctta gtgttgtagc tgttaaattt tcaatagcag ctattggatt agctatctca
    10621 aacacatatc taactgggtc tgtaacttta taatatacaa ctgtatcaat ctgcatagtt
    10681 acattatctt tagttataac tggttgaggt ggaaaatcta ttacaatttc tctaaggtca
    10741 attacatatg ccattttatc taaaaatggt attaagaaat gtacacctgt ttcagctact
    10801 ttttgaaact taccaagtct cattattata cctactttag attgttttat aactcttata
    10861 caagttaaac ttattgctac gactactact attaatacaa tacttaaaac aattttagta
    10921 cccatactat aaatcctcct ttattctatt ggtttgtcac attaactgtg gcgtctactt
    10981 ttttaacaac taattttacc ccttcaattt ttaatacttc tactgtagaa cctttttcta
    11041 tcttttcacc atctatagaa atagccgtcc atgtttcatg ttcaactaca actagacctg
    11101 tgttatttgg agaaatctct tctgtaacaa tacctttttt agacatcatt gcttgtaaat
    11161 tagtgttaga tttatagcct ttatcttttt ttactatttt tttagtagct acgactaaca
    11221 ttgctataga aattactgca aatattaaaa tttgtaagaa aatactctct ataaagctac
    11281 ttaaaaatat aagtattaca gctcctacac taaaccatat caatgttaag cttggtgtta
    11341 acatttctgc tattccaaat aagactgcta ctatcaacca tattaacttc atactatcta
    11401 ccctcttttc atatgaatta taaaacccta tataaattat atgtttatac aatgtttttg
    11461 aatataaatt taaattacaa aacaataaaa taaataaatt aattaatagt attatatcaa
    11521 catactttgt taaaattgtt acaaagtagt atcaaatatc accaattata tatccaacaa
    11581 ctctttcatt gttaatgaaa tgttacttat taaatccgta gcatttaccg tatacattgc
    11641 tttgctcaat ttatctccta tatagccatg tatatatgct ccactaactg tagcttccaa
    11701 tatatccata ccttgaccta taaatgaagt aatcattcca agcaaacaat cacccattcc
    11761 accagttgcc atacagctat ttcctgtagg atttatatat gtttttttac catctgttat
    11821 gacagtttga taacctttta aaagcaccac cagattatat ttttgagcaa attcttttgc
    11881 aacatctact ctatgttctc ttatataccc aattgaatct cctgtcaacc tggccatttc
    11941 tcccaaatga ggtgtaatta caaatctatt tttccattct aaaaacttat aacatctgtc
    12001 cttcataacg ttcaatccat ctgcatctaa tactattggg caattagaat tttctactat
    12061 cttaagtaat ttatcaaatg tttgactatt atctcccata cctggaccaa aaccaattgc
    12121 atcactagaa ttaagtaatt tatttaatct ttcttcttca aaatttaaag tcattgcttc
    12181 tgtaagtcta atagatacct tttcttgcac atcttcacta ctaattaatg ttacaagtcc
    12241 actcccactc ttaacagcag attcagttgc tatgaaactt gcaccataaa atccttttga
    12301 acctgcaact atagatactt ttccaaaatc acttttaaaa ccatgcttat ctcttcttct
    12361 aatattattt tttacaaaag tcttatcagt tatgaactct tcatcatggt attttcttgt
    12421 aataaaatct ggaacaccta tcttttctac aactacatca cctataagtg tgctagtgtc
    12481 atagtttaga aaacctcttt tataaaactc aaagctaatc gttttgtttg ctctaataca
    12541 agttcctaat acatttccat tatcgctatc tatacctgaa ggaatatcta tagaatatgt
    12601 atttttacta ttatcgttta ctatgtcaat aacttcttta aaaataccag ttatatcacg
    12661 ttttaatcca gtcccaaata tagcatctac tacaacatca cttttagata ctctatcttt
    12721 aaaaattgtt aaatttttat tttttataat attttgtttc tcaactttaa taattttatc
    12781 tacttcattt tcatctccat aatttttttc acttaaatca tttttattaa tatttataat
    12841 attaattccc atatttaaaa gtacattgta atttatttta gagcattcac ttagtttttc
    12901 aagattacct actaaaaata cgtttacttc ttttccatat gtatttagat gtcttgctat
    12961 tccaagacca tctcctccat tatttccaac accacataca actgtgtaac tattatacat
    13021 gtctatatcc atatttttca ttgcagatat aaccgcattt tccatcaata caatcattgg
    13081 aatccctact tcttctacac atgcagtatc aacatttctg cttaatttag atgtacctat
    13141 tagcataaat tatcactcct ataaagttaa agacttctta aatacttacc aaaaatatct
    13201 attgaaatct ttttaatccc ataaatatca taaataaaat cactaaaact aagagttttg
    13261 aaataattta aaataacaaa aaattttgaa ttaaaa
//
LOCUS       DAEOTL010000100        13225 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEOTL010000100 DAEOTL010000000
VERSION     DAEOTL010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13225
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.101"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            816..1478
                     /locus_tag="KRH82_003339"
     CDS             816..1478
                     /locus_tag="KRH82_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656600.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1487..3994
                     /locus_tag="KRH82_003340"
     CDS             1487..3994
                     /locus_tag="KRH82_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656601.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQIMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4325..4669
                     /locus_tag="KRH82_003341"
     CDS             4325..4669
                     /locus_tag="KRH82_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656602.1"
                     /translation="MYCLSVVLVIYGIYVFINCTEYIYTMLSTKQLTVTGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGSIENSILKK"
     gene            4907..5593
                     /locus_tag="KRH82_003342"
     CDS             4907..5593
                     /locus_tag="KRH82_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656603.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
     gene            5604..6845
                     /locus_tag="KRH82_003343"
     CDS             5604..6845
                     /locus_tag="KRH82_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8656604.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            6916..7599
                     /locus_tag="KRH82_003344"
     CDS             6916..7599
                     /locus_tag="KRH82_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656605.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            7596..9929
                     /locus_tag="KRH82_003345"
     CDS             7596..9929
                     /locus_tag="KRH82_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8656606.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEATHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(10037..10599)
                     /locus_tag="KRH82_003346"
                     /pseudo
     CDS             complement(10037..10599)
                     /locus_tag="KRH82_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10713..12062)
                     /locus_tag="KRH82_003347"
     CDS             complement(10713..12062)
                     /locus_tag="KRH82_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBG8656607.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSSWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            complement(12099..>13225)
                     /locus_tag="KRH82_003348"
     CDS             complement(12099..>13225)
                     /locus_tag="KRH82_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656608.1"
                     /translation="IRRELHKIPELALEENLTKQKVISYLKEIGIDYMEFTKHNGIMA
                     YILKESADKTICIRADMDALPIEEENNIPYKSIHSGKMHACGHDAHTTMLLGACKVLH
                     SIKDKLNVNVKFLFQPAEEGFGGAKFLVEDGCLENPKADYIFGLHVMPHIETGLIETK
                     YDTLNASVDTIKISIKGKRAHGAYPENGIDAIVTASQIVTSLQTIISRNLEPNNAAVL
                     TIGKIYGGDTHNVICEDVKLEGTLRTLNSKTRNFMIDKIAKIVGDTASAFGCVGTLHV
                     SDENYPAVINEKELVDTVISNTKELLGEEKFILRPNPSLGGEDFSFYTEHCKGAFFHL
                     GCKNEEKGLISPLHTSSFNIDEDCLPIGVMMHVMNTLYFN"
BASE COUNT         5238 a         1503 c         2018 g         4466 t
ORIGIN      
        1 atttcaagta aaataatgtt taaatcagaa atataaataa atattattat aatcgttatt
       61 aaagaccaaa aatcccatct tagaagtttg tatcatatga aacctttata gattatgaaa
      121 gcaataatat agtgtatgat atataaaata agttataaaa gtattttttt agatattcaa
      181 aaagacattg taagttatat taataatatg ggtatcaacg aattttggat ataatgagtt
      241 ttttaactta aagttatgta ataatgaatg taaagaatat ttaatgaaat cattttgttg
      301 gttatgtcta gctgaataca ataatctttt agataaagat tttatatttg aagataggtg
      361 tgaaaaaatt aagaagatat taacatcagc agtttagagg caaagcatgt aaagtaaagt
      421 ctgggtaact aaaagtagta atttagattg taactattgt tataaatatg aaaatgagga
      481 aacaggaaat ataagttagg atgtagaaaa taggttacta aataaaaagc ttaattatat
      541 aatcaaagaa ataggtatat actgtacaat ttcatggtga agaacttttc ctaaataaaa
      601 aggttggtaa aagagatata agaaataaaa ttcaattata agatatggta tgataactaa
      661 aggcactata tggagtgaat aggcggaaga attttttgaa aattataaaa atagtttctg
      721 ttgctacata tcaataagta tagatagaga ttgcaaaatc catagcaaaa atcgaattta
      781 taagtgtaaa taacatgtaa gacaaggagt aaattatgag tattttagag ataaaaaacc
      841 taaataaaat atatggtaaa tcggaaacag aggtgaaagc gttaagtcaa ataaatctaa
      901 aaataaatag tggagaattt gttgtgatag taggtaaaag tggaagtggg aaaagtactt
      961 tactacacat aatggcagga cttgaaactc caacaaatgg tgatgtgatt attgataata
     1021 taaatatatc atctcttgat gaaaagaaaa gatctgcatt acgtaaagaa aagttgggat
     1081 taatatttca atcatataat ttgattccag ttttaactgt tgaagaaaat ataaaactac
     1141 caactataaa tataaaaaat aaagatgaag cttatattaa tgaattgatg gagttactag
     1201 gaataaaaga tagaagaatg tatttgccaa atcaattatc aggtgggcaa caacaaagag
     1261 tagcaatagc aagggctctt gtaaataaac catcaattgt atttgctgat gaacctactg
     1321 gaaatttaga tacaaagaca gagtcagatg tattaagttt attaaaagaa tctcaaaaaa
     1381 aatataatca gacaataata atgataacac ataatataga tataacaaaa tatgctgata
     1441 gagttataga aatagaagat ggatttataa gagagtaggt agatttatga aacttaatta
     1501 tattgtaaaa aaatatataa tgggaaataa gaaaaataca ttattaataa ttgtaagtat
     1561 tgtaatttca acagcgttgt ttttaattat gaatataata agtgaagatg cgacaaactt
     1621 aatgataaat caagctaaaa atgaatttac attaaaacat gcacaatata tcaatccaaa
     1681 agacgaagaa ataaaatata tagaaaataa cacaagtata gataaagttg gaaaatcaat
     1741 gcttttagga attagtgata ttggtaaagg tcaaacacta caaattctat ctcaggataa
     1801 agttgctgaa gaactaaatg atatttacac actagaaaaa ggtaaattac cagtagctga
     1861 aaatgaaatc gctatagatt catggtatat taaacaaaaa aagataaaaa accctatagg
     1921 aaaaaggata acattagatt atagaagaca agggatagat caagaagatt tatatactgg
     1981 ggaaaaagaa tttaaaataa ctggtatctt aaatagtaat cctattttaa aagctcaagg
     2041 aacatcaatt ggccttataa gtaacgattg tgctatcaag aatattccta ctaaaaataa
     2101 atatgatcaa attatgttta cttttaaaaa ggaaaaaaat atacagagac aatcacaaaa
     2161 acttattaaa aatggaaatt tgaatgagaa taacatttat tttaataatg aattattaat
     2221 agctatatct gatagtatga atttaaaaat accttatata atagttaata tagtactagc
     2281 actagcaact atattattaa tttataatat tttttatata ttagtatcaa atagaataaa
     2341 ggattttggg atatttaggg ctttagggtt taatccaaat gatattttta aaataatgat
     2401 tttagaagta tctatatact ctattataag tatttctata ggtctaattt taggtgggat
     2461 aatagctagt ttatcaaggg agtatgttat aggagtaata tacaatgtca actatataaa
     2521 ttctataaaa aaccagaact atataaacac atacataatt tctatattat taagtttagg
     2581 aactataata atatcagttt caaaacctct tatgttatca gttaaaactg atccaatgat
     2641 ttgtataaga agaaataatg aaaaagtgga tataaaacaa aattccttta taaataaatt
     2701 tatgataaaa cttttcaaag actatggtaa catagcatca aaaaatatac aaagaaataa
     2761 gaaacgtaca aatttatcta tagcatcaat ggtaattata tttttcttaa tggcaacaat
     2821 atacacaaag tctactagta actttttaag tgatggtgta ttaaaatatt ggatacaagg
     2881 agattattta ttacataata ttgatataag tactatacgt tcaaataata aaggttatga
     2941 taaaaatgta ctacaagaga taaaggcaat tgatggtgta acaaaagtaa actcatatag
     3001 gcataagtgg tttaatataa aaattgatga taaaagtata aataagaact ctgattattg
     3061 gaaaaaaaat aaagataata ttgaagctag atcagaagta aaagatggaa ttaaggtata
     3121 taataattct tttgaatttt taggaataga agatacagat atactagagg atttcttgat
     3181 aaatggaaag gaaaatatag ataaatttag taaacaacca tatctgtata taacaaagaa
     3241 atccagtgat tcgcttaata taaaaaaagg agatagaata aaagtatact ttgatattat
     3301 agattcaaaa acaaataatt ttaccaaaac aatatctcaa gaatttatag tatgtggaat
     3361 tataactaca ttaccagtaa cctcacaagt gggagctgaa tttggcggag taatatcaac
     3421 aaatcaattt aataagttta caggaatatc atcttatgaa agatttgaca tatggacgag
     3481 taaactagcc aatgataaat atgttgaaag tgagttaaac aaaataacag aaaaaacaaa
     3541 taaaggaatt ttaattccat acaaagctga aacagctgaa tatgaaaaaa ttgataatca
     3601 aaaaacacta attatggtat tagtaactgg aattatagtt atattatctt tatttaactg
     3661 ttgcaatact atagttacta gtattaatag cagaagtagg gaatttgcac tatttagagg
     3721 aataggaata tcaaaacatg aaataaataa aattgttaaa ttggaaagtt atatatatat
     3781 tatagtaagc ttttgtatat ctataatacc tattttaatt gtaagaagta taataataaa
     3841 accttttgaa agtatcaatt taataaattg gaaatttata ggggctatta tcctaatagt
     3901 atttatttta gtatctataa tcatgataac tacactaaaa acattgaata aaattcaaaa
     3961 tgaaaatttt atggaagaaa taaagacttt atagtgaaca gcctataaat taaagaggtt
     4021 ttatatgaat ttaattgcaa ttatcgataa tggtgtagat attgatttta aataatttag
     4081 aaataaaaat aaaataagtt atccaagtta tatgtatgat gtaatagggg tacaatgtat
     4141 agcaaatata aatattggct taataaaact ctactcttaa gtctactgtc gttttaacac
     4201 aagactaata ataagtgtaa cctaaaaatt attgataata caataacctt gtttatgata
     4261 aataacaaat attaagtgtt gtaaagatag taagtttaaa aaaatatcaa agatttcaat
     4321 cacaatgtat tgtttatctg tagtgttggt tatttatggt atatatgtat ttataaattg
     4381 tactgaatat atatatacta tgctatctac aaaacagtta acagtcacag gaaatgaata
     4441 taccattata aattattata tgagtaactt tagtcagtat ataatatttg ctattttact
     4501 tgcatcaatg ggatttgtaa tacaaaagat agtgcatatg catttcagtg agatagaact
     4561 tagtggtaac tattcaacaa ctgttagaaa tataagtgat atctctttag ataatgataa
     4621 tgaaatgttt aatagaggca gtattgaaaa tagtatttta aaaaaataaa taatataaat
     4681 atataaaatg tgattgaata aagcttagaa tacttagtgt attttaagct ttttttatta
     4741 ttaagatttc aaagtattaa attaactata taaaatcata taaaaataat tttaaaatat
     4801 ttaaatcatt gatttcaagg tattgtattt ttaaaagagt aaaaatataa taagttaggt
     4861 atataatata tataaagtaa aaaataaaaa aatggaagtg attgagatga gtagtatatt
     4921 gttggttgaa gatgatttaa gtttgatata tggattagaa tattctatac aaaagaatgg
     4981 atttagtgtt gatgtagcaa gaacagtaga agaagcattg caaatttata aagaaaaaaa
     5041 ttatgattta ctgcttttgg atgtatcctt acctgatggt gatggttttg atatttgtaa
     5101 aagggtaaga gaagcttcta atgtaccaat catattttta actgcttctg atgaagaagt
     5161 aaatgtagtg atgggacttg atatgggtgg agatgattac ataacaaaac cttttaaatt
     5221 aaatgagtta atttcaagaa taaaagcttt acttagacgt tataatttta caagtgaaaa
     5281 tgtaactgaa ctaaaatcaa ataatattac tgttaaatta cttgaaaatc gtgtttttaa
     5341 aaatgaaatt gagcttgagc ttactacagc agaatataaa ttattatgct tacttatgaa
     5401 aaataaaaat attgtactta caagaaaaaa tatattggat aagttatggg atggaaatgg
     5461 tagttttgta gatgataata ctctgtcagt atatgtaaga aggttaagaa ataagattga
     5521 agataatcct gaaaatccaa aaaatctatt aacagttaga agaatgggtt acaaatggaa
     5581 tgttataaag tgagggtgtt aatatgaagg tattttctaa taaagacata aaaatatttt
     5641 ttttggtgat tatatccgtt ttattgatgt ttatagtagt aggtcaaata gtagttataa
     5701 atataactaa tgattataaa agtgcactgt tagaacatga ttataatata gctggatact
     5761 taaatagtat gggtgttgat aaatcaaaaa taccagcagt atttactact aatgaagata
     5821 aatatacttt aaaaggaaaa gaaatcttaa atacagctag atatgacttt ggtacagatg
     5881 atagttttat gccaagtgtg aaattgtttc aaggtaaata tataaaaact atgtttttgt
     5941 atttatttgt gttctttact atgattattt ttatattgta tgtgtatttt tttaggcaac
     6001 agaacaagat agaagaagct agttataaaa ttgattcatt tatgaatgga aatataaatg
     6061 tacggttaaa tacttatgaa gaaggtagtt tatcaaagtt atttggttca atagatgcta
     6121 tgtcaacatc tctaaacaca catatattga aagaaaagca gaataaagaa tttcttaaaa
     6181 atacaatttc agatatatca catcaactaa aaactccact tacagcattg atgatgtata
     6241 atcaaatatt gcaggaagag agtcataata gtgaaattgt tgagaatttt gtgcagaaga
     6301 gtcaaaatga attagagcgt atagaatcat tgatacaaaa cttgttaaag attacaaaga
     6361 tagattcaaa gacaataatt cttaacaaag ctagtgttaa cgtaaaaaag ttgattacta
     6421 aaattttata tagttttgaa actagagcag aaaaagaagg aaagagtatc tctataagag
     6481 gtctagaaaa tacaaacttg ttttgcgatt atgaatggat atcagaagct ttaagcaacc
     6541 ttataaaaaa tgcattagat aatacaaaag agaacgataa aataatgata gaatgggttg
     6601 aaacacctat aacaactatt atttcagtga gtgataccgg aaatggaatt catattgaag
     6661 atatacatca tatatttaaa agattttata ggagtaagtt ttcaaaaagt aatcaaggcc
     6721 ttggattagg gttgccacta gttaaatcta tcatagaaca gcacaatgga accataactg
     6781 tagaaagtaa ttttttacaa ggaagtacat ttactctaag ttttttaaag cttactaata
     6841 tgtaagatag gatacatctt acagtaaggt gtatgaatta ttcttatatt aatcatcaga
     6901 aaggagatag agcaaatgga tattcttgtg gttaataatt tatgtaaaac atatggaaat
     6961 ggatatacaa aagtagaggc attaaaagat gtatcattta cagtttcaaa gggagagttt
     7021 gttactgtag ttggagaatc tggctcaggt aagagtacat tattaaatct tttaggaggt
     7081 cttgatactc caacctcagg aaaaatattt gttgatggta aagaaatatg ttcaatgaaa
     7141 gaagaaaaac agactatttt tcgacgtcgt aatataggtt ttatctttca atcatataat
     7201 cttatacccg aattaactgt ggaacaaaat ataatatttc ctttactact agattacaaa
     7261 aaaccagaca ctatttatct agatgaagta ttgacaattt taggtcttaa agatagaaaa
     7321 agtcatcttc caaatcaatt atctggtggt cagcaacaaa gggttgcaat tggaagagca
     7381 ttgattacaa agccatcaat tatattggca gatgagccaa caggaaatct tgacagtaaa
     7441 aatagcagtg atgtaatttc acttttaaaa gtgacagcag aaaaatataa ccaaactatt
     7501 attatgataa ctcataatac aaatatagct tctacagcag ataggatact acaggtttct
     7561 gatggaatgc ttaaagacct aggggtgaat agagaatgag aagctattta gaactagtac
     7621 cacaatatgc aaaggtacat aagaaaaaaa atagaactac aattttatgt attgtcattg
     7681 cagtatgttt agttactgct atttttggac tagcagacat ggctatacaa tgtcaaaaag
     7741 tacaatttat aaaagatgat ggaaattggc acatagtact taaaaatctt aatgaagaag
     7801 ctatatcaga aataagtagt agagtagata tagctcacta tggtagagga caagtcattg
     7861 ataatggaga gtttaaatca aaggagattt tgatacaagg tttagatgaa gatttagcaa
     7921 aacaattagg tctagaaata ataaaaggtc gttatcctgt tgtggagaat gagactttaa
     7981 tagatgtaga tgcagttaaa agctttaatc taaaagtagg agattttatc aaaataaaat
     8041 tagcagatgg tagaaataaa aattataaga tagtaggtga atattcatca ttatcaagct
     8101 taagagcctc agataagcat ggattaatgc tttcaatatt aggtacacaa gctatcaaaa
     8161 aatcagaaac atatgattat tattatatta catttaaaga caaggttaat attagaaaag
     8221 ctacttctga tattaagaat acctttaatt taagtgataa acaaatcggt aaaaatgaaa
     8281 aattactttc tattataggt caaggtgact ctgattattc taaaccactt tacttaacag
     8341 caggaggact ttttatactt gtgttaatag caagtattat catgatatat aatagcttta
     8401 atatgggtgt aatagagaga ataaagtttt ttggactatt acgttgcttg ggagcatcaa
     8461 aactccaagt caaaaaattt gttgttttag aaagtttaat tctaagtgta aaggctattc
     8521 cactaggatt gttattagga tgtattgtaa ccattatatc ctctatattt ctcaaatatg
     8581 tgaatacaga gttatttggt tcgatgccaa ttttaaaggt tagctttatt ggtattgtgt
     8641 ttggaataat agtaggattt ttaacagtaa tattatcagc tattgttcca gcaaaaaaag
     8701 cttctggggt gtctccacta agtgctatac gtggtaatct aatgttcaaa gaaattttaa
     8761 ctagtggaaa agcaagtaaa attgctaacg caggaagttc taaaattgat gtttctatgg
     8821 gaataaatca tgccttttca agaaaaaaat cttttatact tatgacttct tcatttgcta
     8881 ttagtattgt attgttttta ggttttagtg tatttataga ctttatgtat caggcactta
     8941 aacctataaa accagaagct actcatatat ctattgttga cgctgacttt aagtctgttc
     9001 ttactaaaga cgatattaat gaaataagta atatcaaagg aataaaaaaa gtatacagta
     9061 gaatgatgac ggatgtagag gctacataca ataataagga ggcaacatct cagctaattt
     9121 cttatgaaaa aaatcaattt gactgggcca aaaagtatct agtaaaaggg gaaatcaatg
     9181 aagataaatt agagtcagaa aatatcggat tggtagaaga aggtcatggg tttaatattg
     9241 gagataagat atatattaaa aatggaaatt ctaagaaaga gatagaggta gcaggtatac
     9301 tttcttcaat ttcatttgat gttaaagaca aatatattgg aaatattata acatctgaaa
     9361 atacttttac tagtataaca gatataaaag actatataat aattgatact caagttgatg
     9421 aagatgctcc tgaagattta atccaaaata taagaaatgt tctagatgat aatttagagg
     9481 ttcgagataa gcgacaaggt aacttagagg ctaaaaattc attttacact atggcagttt
     9541 ttgtatatgg gtttgtattt ataattgcga ttataagtat gtttaatatc ataaacagta
     9601 tgaatataag cgttacaagt agaataaatt actatggtat tatgcgtgca ataggcatgt
     9661 ccaataagca attaagaaaa atggtaatag tagaatcaag tacatatgct gtaagtggct
     9721 gtttattggg gagtgtactt ggattaatat tacatagata tatatttgta tccttagtaa
     9781 cattaaaatt ccatatagac tggcaaatac cttttgattt actgtttatc attgtagtaa
     9841 ctatgataat aataactttg cttgcagtaa gaaaacccat taaaaagatt tgtgaattag
     9901 acataataga ggtagtaaat gcacaataaa tataagtagt aatttaaata gaggtagtaa
     9961 tttaaataaa aaatcgaagt aaatatgaaa tagaaaatat ctttcataat ttacttcgat
    10021 ttttgtgtta tataatttac tttagataag ttccatcttc atcttgataa attaagtctt
    10081 tcttcataag tactccaaga gcacgtttaa aattttctta cttgaattaa ataagataga
    10141 aatatcttta ggatcagatt tatcattgaa tctcatatat ccatctgaac cttctaaata
    10201 gcttaaaatc ttattttcta aggtatcaag ttcatctttt ctgtttcctc taggagaaag
    10261 tcctaattta ccatcatcgt atatttttat aacatgtaaa ttttcaagaa catccccagc
    10321 ttttaattct gtaaagtatt cattatgaag gattacacca gcatatttat tgtcaacaca
    10381 tatcatagca gagttgttgg tttggaatcc atatacaact ccatttacaa catctcctac
    10441 attgtaagta tggtctgttt ctaaatatga atctatgtct gtagtagcag ctattcttcc
    10501 gcttttatcc aagtatatat agaataaata tttttcatct ctaaacaatg gataagtctt
    10561 agctttaaaa ggaactagta tgtcttttgt aagtcccata tctataaaag taccaatatc
    10621 cgtgttatca actactttta gatacgtaac atctccattt ctaattattt ctatagtatt
    10681 agaaaaataa tttttaaata gtttgtaaaa tattattgaa ttttttctct cgaaatatat
    10741 aatttagaat cttctgattt atttttatgc tcgatttcct tatttttttt cataaatata
    10801 tatagaggag ctattaacaa cattgcccct aatcctatta aaactctatt ttgagttata
    10861 ggttttgaaa tatcttctgc ccaagcttgt tgtaacaacc atgagctacc taaaatagct
    10921 accattggta taacaggacc aaatggaatc ttaaaagagg ccttaacatc tgttcttttt
    10981 cttaaaacta ttactgataa acaagttggt atgtactgag caaatcttgc aattacactc
    11041 attactgcaa gttgttcaaa acttccagtt agcacaagtg gtatacaaca aattaaagat
    11101 attattattg ctacatatgg agcaccatat ttatttgttt ttcctataaa tgcaggaaga
    11161 gaaccttctt ctgctagaga agaaccacat ttaggagtta ctattgatga acctatattt
    11221 ataccaaata tagatattaa tgttgctaca gatatgaaaa ctttaccata attgcctaaa
    11281 aatacacttg aagcatctgc aattggaata ctgttttcaa atagtctatc tccaagtata
    11341 cccatacaga caatttgaat taatatataa attattgcac atataaatat tgtggttatt
    11401 aatgcgactg gaagattttt tttaggattt tccatttctc cacttgccac aataaatgat
    11461 tcaaagccgg taaatgcgta aaatactaat ataatggctg gacccatact agagttaact
    11521 acatttcctg aaggaacaat atttacaaat tttataaaga atattccaac tattataaaa
    11581 actattaatg gtactaattt agctatagtt attacattat tcattatctt tgtgctttta
    11641 attccaaata agctatttat tgaaagtagt gttacgagta ttgcagctat ataacctttg
    11701 tattcagtgg cagattctgg ccaaaatgaa cctaaagctg ttgcaaatcc tactgctaga
    11761 gtagaccatg atataattct aataacccaa gacattgtac caacttcaaa tcctataaaa
    11821 tctccaaaag cttttttgga gtatagatat gctcctccat tcttatcaaa catgcttcca
    11881 acttctgcaa aacataaaag tattgataga actaagagtg tagcaaaaat gtatataaac
    11941 atactgtttt gacctgctag attataaact ttacctggta gtaagaatat acctgaacct
    12001 attatgctat taatccctaa taatatcata ctaaatagac ctaatttctt agctttttcc
    12061 atattaattt atctcctatt cttttattaa ttactgtact aattaaaata caaagtattc
    12121 attacatgca tcataacacc tattggtaaa caatcttcat ctatattaaa gctagaggta
    12181 tgaagaggtg aaattaagcc cttttcctca tttttacatc ctaaatggaa gaatgctcct
    12241 ttacaatgtt ctgtgtaaaa agaaaagtct tcaccaccta aagacgggtt tggtctcaat
    12301 ataaattttt cctctccaag taattcttta gtatttgata taactgtatc tactaattct
    12361 ttttcattta taacagcagg atagttttca tcacttacat gtaaagtccc aacacaacca
    12421 aatgcagatg cagtgtctcc aacaatttta gctattttat caatcataaa gtttcttgtt
    12481 ttgctattta aggttcttaa agtgccttct aattttacat cttcacatat tacattgtgt
    12541 gtatcaccac catatatttt acctatagtc aaaacagcag cattatttgg ttctaagttt
    12601 ctacttatta tagtttgtaa tgatgtaaca atttgtgaag ctgtaactat tgcatcaata
    12661 ccgttttcag gatatgcacc atgagctctt ttacctttga tacttatttt tatagtgtct
    12721 acactagcat ttaatgtatc atattttgtt tcgataaggc ctgtttctat atgtggcata
    12781 acatgaagtc cgaatatata atcggccttg ggattttcta aacacccatc ctcaactaaa
    12841 aattttgctc ctccaaaacc ttcttctgct ggttgaaata agaattttac atttacatta
    12901 agtttatctt ttattgaatg taaaacttta catgctccaa gtagcatggt tgtatgtgca
    12961 tcgtgaccac aagcatgcat ttttccagag tgtattgatt tataaggtat gttgttttct
    13021 tcttcaatag gaagagcatc catatctgct cttatacaaa tcgttttatc tgcactttct
    13081 tttaaaatat atgccataat tccattgtgt tttgtaaatt ccatataatc aattccgatt
    13141 tcttttaaat aagaaattac cttctgttta gtaagatttt cttcaagagc taattctgga
    13201 attttatgta attctcttct tatgt
//
LOCUS       DAEOTL010000101        13107 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEOTL010000101 DAEOTL010000000
VERSION     DAEOTL010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13107
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.102"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            9..473
                     /gene="bcp"
                     /locus_tag="KRH82_003349"
     CDS             9..473
                     /gene="bcp"
                     /locus_tag="KRH82_003349"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBG8656609.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            483..1226
                     /gene="yaaA"
                     /locus_tag="KRH82_003350"
     CDS             483..1226
                     /gene="yaaA"
                     /locus_tag="KRH82_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBG8656610.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            1354..4011
                     /locus_tag="KRH82_003351"
     CDS             1354..4011
                     /locus_tag="KRH82_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBG8656611.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      4065..4167
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            4277..5542
                     /locus_tag="KRH82_003352"
     CDS             4277..5542
                     /locus_tag="KRH82_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBG8656612.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            5572..6462
                     /gene="metA"
                     /locus_tag="KRH82_003353"
     CDS             5572..6462
                     /gene="metA"
                     /locus_tag="KRH82_003353"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBG8656613.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            6953..7396
                     /locus_tag="KRH82_003354"
     CDS             6953..7396
                     /locus_tag="KRH82_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656614.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            7427..9244
                     /gene="ftsH"
                     /locus_tag="KRH82_003355"
     CDS             7427..9244
                     /gene="ftsH"
                     /locus_tag="KRH82_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBG8656615.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            9422..12124
                     /locus_tag="KRH82_003356"
     CDS             9422..12124
                     /locus_tag="KRH82_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBG8656616.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            12158..12856
                     /locus_tag="KRH82_003357"
     CDS             12158..12856
                     /locus_tag="KRH82_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656617.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         5140 a         1510 c         2392 g         4065 t
ORIGIN      
        1 agatatttat gttgagtata ggaacaaaag caccagaatt tacactagaa gataaagatg
       61 gaaataaggt aagtatgtca gattttaaag gtaaaaaagt agtagtatat ttttatccta
      121 aagataatac accaggatgt acacgtcaag cttgtgcttt tagaaatgca tatgatggat
      181 ttaaaaagga agatatacaa gttattggga taagtaaaga tagtataaaa tcacatcaaa
      241 aatttgcaga aaagcatgaa cttcctttta ttttactttc tgaccctgac ttagttgcta
      301 taaaagcttt tgatgtatgg aaagagaaaa aaatgtatgg aaaaactgca ttgggagttg
      361 tacgtgcgac atatattata gatgaaaatg gaattattga aaaagtcttt gaaaaagcaa
      421 aaccagacac aaatgcacaa gagattcttg aatatttgga aaaacaggag taataagaat
      481 ttatgattat aatgttatca ccagctaaaa atatgaagaa tatagaagta tttgatagag
      541 atttgagttt gccttgcttt atagataaca caaaagaaat agtggaaaat ataaagacat
      601 ttggtataga agattttaaa aataaaatga aaattaatga aaaattagct gtattaaata
      661 aaaatagatt tgaaagcatt aaatttgata gattaggaaa ccctgcaatc ttaacttatg
      721 atggaataca atataaaaat atagaagcag aaaattttac aaggaaagat gaagagtttg
      781 caaatagctg tattcgaatc ataagtggat tgtatggtgt tgtaaaacca tatgatagta
      841 tatatgaata tagattagaa atgcagacaa aattacaagt aggtgagttt aagaatttat
      901 acgaatattg gggaaatcgt atatataaag aactaatcaa agaaaaaaca gctatcgtta
      961 atctttcatc aaatgaatac agcaaatcca tagaaaaatt tattaaagat agtgatacat
     1021 atattacatg tacttttaaa gtaaataaaa atggcatatt gaaagtggaa tctacacaag
     1081 caaagaaagc tagaggtatg atgacaaaat acattgtaaa aaataggata agagatattg
     1141 aagaactgaa aaagtttgat ttagaaggtt ataagtataa agaaaactta tctaacaata
     1201 gtgaatacat atttgtaaaa gagtagaagt tttgttaaat attaaatggc attgttaaat
     1261 ttaggtaaaa tatacttagt gtgtattgaa ttgaacttga ttttaaaata taattattct
     1321 taaattaaaa aaagaaagga gtggtcttcc aaaatggaaa atcacaaaca gatgccttgg
     1381 cattcaagag caacgcatga aattttagaa agtctagatt catcagagga ggggctcacc
     1441 gataccgagg cggaaaaacg gcttaaagag aatggcttaa atgaacttag aaaaaaacca
     1501 cctagaacaa ctttacaaat gctttggagt caaattacag atgctatggt tatgatacta
     1561 ataggagcag caatattatc tttgatattt ggcgaattta cagaagcttt tgtaatacta
     1621 ataattgtaa cagtaaatgc agttattgga attgttcaag agaaaaaagc agaatcatca
     1681 ttagaagcat taaaaaatat gaattcacct acagctcgtg ttatgcgtga tggtgaagaa
     1741 aatgttattc cagcaagtaa tcttgtagta ggagatattg tttttttaga agatggagct
     1801 atggttccag cagaccttcg tttaatagaa acatcaagtt taaaaattca agaggcttct
     1861 ttaacaggag aatctgttcc atcagaaaaa gatgcagata caatcttacc taaagaatgt
     1921 gtattaggag accgtagcaa tatggcgtat acatcttcaa tagtcacata tggtagaggt
     1981 gtaggtgttg tagtagcaac tggtatggat acagaagtgg gtaacatagc acatctttta
     2041 gattcacaag atgattttga tactcctata aaacgtaaac ttaatactgt tggaaagaca
     2101 ttaagtgtca taggtattat tgtatgcgtt gttatatttg caataggtgc attttatcag
     2161 agacctctct tgccaatgtt tatgattgca atttcccttg ccatatcaat tattccagag
     2221 ggattacctg caacagctac tattgtaatg gctttaggcg tacagcgtat ggctaaaaga
     2281 aatgctttaa ttagaaaatt acctgctgtt gaaacattag gaggagctac agtaatatgt
     2341 tgtgataaaa ctggtacatt aaccttaaat aaaatgactg ttacacatat tgctgtcaat
     2401 ggagattttg aatctggaaa agtgacatca atagatactg catctgaaaa acatccatta
     2461 gtgtataaag agattgttta tgctggtgca ctttgtaatg atgcatgtat taatccagat
     2521 aaaacagatg aaatattagg tgacccaaca gagggcgcat taatttttat ggccaaaaaa
     2581 tttggaatag atcaagaagc tcttgaagaa gaatatccac gtgtatttga acagcctttt
     2641 gattcagata gaaaatgtat gacaactgtt cataatatag atgaaaagat tattgcttat
     2701 actaaaggag cagtagacga aattcttgac ctatgtacta aaatattaac ttcaaaaggt
     2761 gaaagaaaca ttaccgaagt ggataaaaag aatatacacg aattatgtct taacatgtct
     2821 aaagatgcat tgcgtgtact tggttttgct aagcgtgaga tttcatctat accaaaagaa
     2881 gatagtgaaa atatagaata tgatttaaca tttataggta tggttggtat gattgaccca
     2941 ccaagaactg aggtaattga tgcagtaagt acttgtaaag aagcaggtat aagaaccata
     3001 atgataacag gtgaccataa agttactgcc acaacaatcg ctcatgagtt aggaatatgg
     3061 agtgaagaaa atactgtgat atctggtgat gaacttgata atttgagtga tgatgaacta
     3121 gatgaagctg ttaaaaatac tacagtattt gctcgtgtat ccccatttga taaacttaga
     3181 attatacaat ctctaaaaag aattggagaa gtaccagcaa tgactgggga tggtgtaaat
     3241 gactctcctg ccttaaagtc tgctgatatt ggtatagcca tgggtataag tggtacagat
     3301 gttgcaaaag attcttctga catgatttta atggacgata gttttacaac aattgcttat
     3361 gcaataaaag aaggtagacg tgtatataga aacatacaaa aagttataca atttttgctt
     3421 gttggtaata tagcagagat acttacgttg tttgtagcaa tattattaaa ttgggatact
     3481 ccgcttcttg ctgttcatat tctatgggta aaccttgcaa ctgctacgct tccagccctt
     3541 gctcttggag ttgacccacc aagcagaaat ataatgaagc accagccagt gaaatcaacc
     3601 actttgtttg aaaaaaatct tatacaaaga gttgttaccc aaggtatatt tgtggcaata
     3661 atgactattt tagcatataa aattggtctt aatatagaaa atcattctgt aggtcaaaca
     3721 atggcatttt gtgtattagc attttcacag atgttacgag catttagtca gcgttcaaat
     3781 acagattcaa tgtttaatag aaataatggt aaaaatccat ttcttttaat ctcattttta
     3841 acttctgcat ttttaatagc agtaatacta tttgtacctg tttttagaaa tgcttttaac
     3901 ttaacagttt taaataactt agagtggctt ataacgattg ttttagccat aatgtctgta
     3961 attcaagtag aggttgggaa aattattaaa agaaaaaaat taaaaaaata gttgacaaaa
     4021 ttaggaaaaa tatataagat ataaaacata gaaaaattaa ataaatctta tccagagagg
     4081 tggagggact ggccctatga aacccggcaa ccagtatatt tatatacatt ggtgctaaat
     4141 cctgcggcga aagctgagag atgagtataa ttaagcttat acagagcctg agttatatac
     4201 tcaggcttta tttattttaa ctctcatctg gtaaatagtt taattttttt tactaaaatc
     4261 taagggggat acaagaatgt ataataaaga aacaatatgt gtgcaaggaa attataaacc
     4321 aggtaatgga gaaccaagag tactaccttt atatcaaagt acaactttta aatatagcag
     4381 tatagaccaa cttgctgaat tatttgattt aaaagttgat ggacatatat attcaagaat
     4441 aagcaatcct actattcaag cttttgaaga aaaaataagt ttactagagg gtggagtatc
     4501 ttctgtagct gtatcatcag ggcaatctgc aaatatgttg gcagttttaa atatatgtaa
     4561 atcaggagat agtatacttt gttcttcaaa agtatatgga ggaacattca atttactagg
     4621 acctagtctt aaaaaatttg gtatagattt aatatcgttt gacttagatt caagtgaaga
     4681 tgagatagta gaacttgcaa aggaaaatac taaggttgtg tttgcagaaa cacttgcaaa
     4741 tccaactctt gaagtcatag attttgaaaa aatagcaaat gtagctaaga gaattaatgt
     4801 tccatttatt gttgataatt cattagcatc tccagtgctt tgtaaccctt taaagtatgg
     4861 agcaaatata gttactcatt ctaccacaaa atatttagat gggcatgctt caagtgttgg
     4921 aggaattata gtggatggtg gaaactttaa ctgggataat ggaaaatttc cagaattagt
     4981 tgagccagac ccaacatatc atggtataag ctatactcaa aaatttggaa atgccgcata
     5041 tgcaactaaa gcaagagttc agttgcttag agactatgga aattgtttaa gcccattcaa
     5101 tgcatatctt actaatttaa atgttgaaac actacatctt agaatggaga gacatagtga
     5161 aaatgcactt aaaatagcta gatttttaga aaaacatgaa aatgtagatt ggattaatta
     5221 cccaggactt gaagataaca agtattatga gaatgccaaa aagtatttat caagaggatg
     5281 tagtggtgtt ttatcatttg gagtaagagg tgggttagaa aatgccaaaa aatttgtgga
     5341 aaaattacag atagcatctt tggttacaca tgtttcagat gtaagaactt gtgttataca
     5401 tccagcttca actactcata gacaattaac agaagaacaa ttaattgcat ctggagtatt
     5461 gccttcacta ataagattat ctgttggaat agaaaatgta gaggatttaa tagctgattt
     5521 aaatcaagct ttaaatttct aatattctaa gagaaagaga agtgaaaaga tatggcttta
     5581 atactaccaa agggattacc tgttattaat aaattattag atgaaggaat agatgtaatt
     5641 tataaagaag attttaaaaa ggaattaaaa tatgaagaaa acatagacac taagatagct
     5701 atactaaatc taatgcctat aaagatagat acagaattag atttactaag aaggatagat
     5761 aaaacaggat tcaacgtgtc tgtggaattt attaaaattt caacaagaga aagtaaaaga
     5821 agttgtaatg aatatgttaa agaattttat aaaacatttg atgaagccaa aggagagtat
     5881 tttgatggct ttataataac aggagctcca gttgaacaaa tggagtttga agaagttgat
     5941 tattggaatg aactagaaga aattatggat tattctaaga gaaaaactaa atctacatta
     6001 tatatatgtt gggcagctca agcaagtctt tacaaatact acaatgtaaa aaaacttcca
     6061 ctaagtcaaa aatgttttgg agtatttaag cataaggtag ataaagatag taaaatagta
     6121 gatggatttg aaaatgaatt ttttgctcca cattcaagac atactactgt aaatattgaa
     6181 gctttgaaag agaataaaga gttgagcatt gtgagtcatt ctaaagaagc tggtccctat
     6241 ataattacaa attcaagaga tgtgttcgta atgggtcata gcgagtatga caaatacact
     6301 cttgataaag aatataagag ggatataaat aaaggagata aaatatctat acctcaaaat
     6361 tactatatta atgatgaccc ttcagaagag ccaactgtaa aatggaaaaa acattcagaa
     6421 ttgttgttta gaaattggat aaaaaactat ttgatacaat aaattttaag agtatataaa
     6481 tgttaactaa aaaaatatag aaatttatag gtataaagtt aatcttaatg atactttata
     6541 ccttattttt ttaaaatttg accttataat agtagtttta tattttaaga aaatcacttt
     6601 aggtgtatgt agatagaggt ggctttaatt ttatatatgg tgcgataatg ggagactaaa
     6661 cctttatagt atcaataaat ttgtatttta acttttaaaa gagattaaaa agggagaaat
     6721 cagtgtaaaa tatatatata gattttttat taaattttat taaaaatatc ctgtataaaa
     6781 ttaaatatca ataagataac aaaatttcaa ttgaagttac aatattgtaa ttgacaataa
     6841 atacttaata ctataatatt taatacatta aacattatag tgttaagtat ttatttacag
     6901 tatgcacttc agcctaaatt tgaaataaag tattttcgta gggagcgttt gtatggatga
     6961 gatgagtttt aagaaagagc tactagagtt gactagagat ataaatatga aatttacaac
     7021 tttattaagt gatttttatc agccacttgg tattacagca gtgcaagctt tgattttatc
     7081 tgagttatgt gaacatggag aaaaaaaaat aagcgattta gggaagaact taaacatgac
     7141 aaatagtaat gtatcagtaa tctgtcaaag gcttgaaaaa aatggctttt taaatcgcat
     7201 aagagatata gaagaccaac gaattgtaaa agtaaaagtt acaaataaat cattggatat
     7261 acaagaacat atttcaagta gtatttttga tagttatttt gaaaatatga ccagtgaaaa
     7321 attgcaagat atggaagata taatagaagg tttagagaaa ttaaataaac ttttaactta
     7381 cattgattgc aaataacata aaaataattt aaaggagaat aaaattatgg atgaacataa
     7441 accccaaaaa aggtcagcac tctattatta tacagttata ataatagtag taatgttttt
     7501 aaatgcttta atatttccaa gtttaatgga taaaaaaatg gttgagattg actatggaaa
     7561 gtttctcaca atgttggata caggaaaggt taaatctgtt gagatagaaa ataatagaat
     7621 agcaataaat ccatctagta gcaaggataa gaatatatac ataactggta gaatggatga
     7681 cccagaattg gtagatagac taaaaaatgc aaaagtagaa tttactaagg ttattcctaa
     7741 ggaaaattca cctcttttaa gtattttact tacatggata atacctatag gtattcttat
     7801 gctatttggt aacttaatga tgaagtctat gcaaaagcga atgggtggta atgctatgca
     7861 atttggaaaa agcaacgcca aaatgtatgt atctgctcaa agtggaaaaa gatttaatga
     7921 tgtagctggt caagatgagg caaaagaagc tttaactgaa atagtagatt tcttacacaa
     7981 tccagaaaag tataaaaaga taggagcaca aatgcctaaa ggagcacttt tagtaggacc
     8041 tccaggtaca ggaaaaacac tccttgcaaa agctgtagca ggtgaagcaa atgtaccatt
     8101 tttctcaata tctggttctg agtttgttga gatgtttgta ggaatgggag cttctaggat
     8161 tcgtgattta tttaaacaag caaaagaaaa agctccatgt atagtgttta tagatgagat
     8221 tgatactatt ggtaaaaagc gtgataatgg aagtggatta ggtggaaatg atgaacgtga
     8281 acaaacttta aatcagttgt taagtgagat ggatggtttt gatggtggaa ttggagtagt
     8341 aatacttgct gctacaaata gacctgacag tcttgacaaa gcattacttc gtccaggaag
     8401 atttgataga cgtataccag ttgaacttcc agaccttgga ggacgtgaag ctatattaaa
     8461 ggtacatgct caaaatgtaa atgtaagctc agatatagat tataatgcaa ttgcaaggtc
     8521 tacatcagga gcatcaggtg cagaacttgc aaatattgta aacgaagcag cacttttagc
     8581 agttaagtct ggcagagata tagtagaaca acaggatttt gatgaatctg ttgaaactgt
     8641 aattgctggg tatcaacgta aaggagctgt aatttcagat aaggaaaaga aaattatagc
     8701 atatcatgaa ataggtcatg cacttgttgc tgctatgcaa aaacattctg cacctgtcca
     8761 taagattact ataataccta gaacttcagg agcattggga tatactatgc aagttgctga
     8821 agatgagagt gtacttatgt ctaaagaaga agcaattgat aaaataacta cttttacagg
     8881 tggtcgtgct gctgaagagg ttatctttaa cacttgtaca tcaggagcat caaatgatat
     8941 agaacaagct actaaaattg caagagctat ggttactcgc cttggtatga gtgaagagtt
     9001 tgatatggtc gctcttgaaa ctgtaagcaa tcaatattta ggaggagata cttctcttgc
     9061 ttgttcttcc gacactgctg ctaaaataga tgaagaggta tttaaaatag taaaggcttg
     9121 tcacaaaaat gcaattgaaa tcttagaaaa taatattgat aaattgcatg aacttgctaa
     9181 ttatttatta gaaaaagaaa ctattacagg tgatgagttt atggaaatac ttaacttaaa
     9241 ctaaaatgat tatacacaag ataaaaatgc ctattgttag gcatttttat tttacaacta
     9301 aattttttaa attcatattt aaatctttac ataatcttaa tcattaaaaa tacatcttaa
     9361 ctacaatttt atatcggaat tgatattata atagtaatga atggtgtaag gaggtttttt
     9421 aatggataga cctaatcctg atattctatt agaaaaaatt aaaaatgaag aagaaaaact
     9481 aagtagaggt caattaaaaa tattctttgg ttatgcagct ggagtaggaa aaacctactc
     9541 tatgttggaa tctgcacaaa atttaaaaaa agtgggtgta gatgtagtag ttggatatat
     9601 tgaaccacac actagaccag aaacattggc tttacttgat ggcttggaaa ttcttcctgt
     9661 aaaggagata gaatataaat ctataaaact aaaagaattt gatttagatg ctgctttagc
     9721 aagaaaacca gaagttatat tagtagatga atttgcccat tctaatgttg ctgggttaag
     9781 gcatacaaaa agatggcaag atatagaaga attgctgtta gcaggcataa atgtctacac
     9841 tactgtaaat gtacaacatt tagaaagtct aaatgacatt gttgagataa ttacaaacgt
     9901 atcagttaaa gagactatac cagataagtt tttggataca aatacacagt tagaacttat
     9961 agatgttgaa cctgatgtac ttcttgaaag gttcaatgaa ggtaagatat ataagaaaga
    10021 acaagctact agagcaaaaa ataatttttt tataaaagat aacctggttg cacttagaga
    10081 aatcgcactt agaaaaactg cagagagagt taataaagaa gttcaaatga ccagactatc
    10141 aaagggtgat gtaactgtaa tacctacatc agatacactt cttgcatgta taagtccatc
    10201 tccatcttca gcaaaagtta ttagaactgc atccagaata tcagacagta catttgcaaa
    10261 atggatagct ttatatgttg aaactccaaa cacagcaaga cttccatttg atgaacaaaa
    10321 acaactacaa aataacctaa aattagctaa gaaattaggt ggagaaataa ttgttttaca
    10381 tggtgaaaat ataatagagc aaatacttag aattgcaaag ctgagaaatg taacaaaaat
    10441 tgtaataggt agaaatcatt caagtaataa aagatttagt aaaagattta aaaaagatat
    10501 agttgacaaa ttaattgatg aagttgatta tatagatata catataattc catataaatt
    10561 tgcctcagat gttaaataca aacctaaaaa ggataaatca tcaataaaat ctaaatttaa
    10621 aattagcaaa gttgatttta taaaacttat atttattact ttgatgataa gtattttagc
    10681 atatgcagta caaagcatgg gatttataag agaaaatata ttgttaatat atatgttggg
    10741 tgtagtttta gtttctatgt ggactaaagg gtatagtaca ggtataataa gttctgtatt
    10801 taatatagtt cttttaaatt atttttttac agcaccatta tatacattat ctatagcaga
    10861 ttcaaactat atagtaacac tggttgtatt ctcaatagta ggtataataa ctagcactct
    10921 tacgtctaag atacagcatg aagcagaaac tgctgctaaa agagaagaaa atacaaaaat
    10981 gatatatcaa ataattaagg gatttttaag attatcaaat aaagatgata tagtaaacaa
    11041 aggtatagaa cttttgtctc ttagcttaag tagagatgta atttgttatt taaatgtaga
    11101 taagcataat aaatcaaagc tttacaaaaa aaatactaat aataaggata aaaatgattt
    11161 ggatagtgaa gatgaaaaag ctgttgcaag ttgggtttta tccaattcaa cagtggcagg
    11221 aaatgacacg gatacacttc ctggttcaaa gggatactat ataccaattg taggaatgaa
    11281 tttaacttta ggagtagtgg gaatatcatg tattgattca aaattggata cagaagatat
    11341 aagcttaatt gaaacaataa ttgctcaaat ggcaatagcg cttgatagag aaatcttgtc
    11401 agaagctaaa gaaaatacca atcttgagat tgaaagggaa agattaagaa gtaatctttt
    11461 aagagcagtt tcgcatgacc ttagaactcc actagcagga atatctggtg cagtaagtac
    11521 aattataaaa aacaagggca ctataggtca agatataata gatgaattac ttagtggtgt
    11581 atatgaagat actcagtggt taataagact tgttgaaaat ttacttagta tgaccaagat
    11641 agatgaaggg aaattggaag ttaaaaaaca ttctgaactg gttgaggaaa ttatatcaga
    11701 agcgttacaa aaaataaaaa aaagaattga aaatgcactt atagatatta atataccaga
    11761 acagatatta tttgttccta tggatgcaaa attaatagaa caagttttaa ttaatttaat
    11821 agataattct ttgaaatatt caaaggaaga ttgtaagata gagataaatg tatatgagaa
    11881 agatgattat gtttggtttg aagtatctga taatggtcct ggtatatcaa aggaacttaa
    11941 aaagcatatc tttgacagat tttttactgg agaagaagga gctaaagatt ccagaaaggg
    12001 tgttggactt ggattatcaa tttgtaaatc tataattcaa gctcataaag gtgaaattat
    12061 ggtagaaaac aataaagata agggttcaac ttttaagttt agtttgccta aggaaaatga
    12121 atagttttaa attttaaaat tagttttgga ggaagaaatg agtaaaaaac ttatattgtt
    12181 agtagaggat gataagacaa taagaaaatt tatatctact gcacttttaa cacaggatta
    12241 tgatgtcaag gaggctataa ctggaaaaga aggtatatct atagctgtct catattctcc
    12301 agatgttgtt cttttagatt taggcttaga agatatggat ggaatagagg taataaaagc
    12361 tatcagacaa ttttcaaata taccaataat tgtagtttca gctagagagc aagatagaga
    12421 caaggtagaa gtatttgatg caggggcaga tgattactta acaaaaccat tttccatagt
    12481 agagttatta gcaagagtaa gagtagcatt tagacattca caagtagaag ctcaacaaaa
    12541 agatgatgtt aaatctacgt ttgaagtaga taaattattg attgattttg ataaaagaaa
    12601 agttattgtt gatgatgttg aagtccattt gacacctatt gaatataata ttctttcatt
    12661 acttgcaaag catcatggaa aagtgcttac tcataatttt ataataaaag aaatatgggg
    12721 tagtgttata gggaatgaga ctaagtcttt aagggttttt atggcaacgt taagacgaaa
    12781 aatagaaaaa caacctgcaa acccaagata tataattaca gaagttggtg taggatacag
    12841 attaaatgat gaatagttgt aatatattaa ttattagatt atgtgcttat taatatatat
    12901 taaaattata tagtttagtt aaaataagaa tgaagtgtat gtgcttgttg tcagtttagc
    12961 acatgcattt tattttttag cttttttagt atcaataatt ttttagtatc aataatatga
    13021 aatatgtttt aaaataagta tatagtgtaa tctgtaataa aaactttggt taaataataa
    13081 atgtatttaa cacttacctt ataataa
//
LOCUS       DAEOTL010000102        12867 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEOTL010000102 DAEOTL010000000
VERSION     DAEOTL010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.103"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            131..319
                     /locus_tag="KRH82_003358"
     CDS             131..319
                     /locus_tag="KRH82_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBG8656618.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(479..631)
                     /locus_tag="KRH82_003359"
     CDS             complement(479..631)
                     /locus_tag="KRH82_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBG8656619.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(729..1205)
                     /locus_tag="KRH82_003360"
     CDS             complement(729..1205)
                     /locus_tag="KRH82_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBG8656620.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1424..2185
                     /locus_tag="KRH82_003361"
     CDS             1424..2185
                     /locus_tag="KRH82_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8656621.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2445..4373)
                     /locus_tag="KRH82_003362"
     CDS             complement(2445..4373)
                     /locus_tag="KRH82_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8656622.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4607..5059
                     /locus_tag="KRH82_003363"
     CDS             4607..5059
                     /locus_tag="KRH82_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8656623.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            5062..5370
                     /locus_tag="KRH82_003364"
     CDS             5062..5370
                     /locus_tag="KRH82_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBG8656624.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5484..6590
                     /locus_tag="KRH82_003365"
     CDS             5484..6590
                     /locus_tag="KRH82_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBG8656625.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENIEFDEIELDIM"
     gene            6665..9343
                     /gene="mngB"
                     /locus_tag="KRH82_003366"
     CDS             6665..9343
                     /gene="mngB"
                     /locus_tag="KRH82_003366"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBG8656626.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEYSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9660..11993)
                     /locus_tag="KRH82_003367"
     CDS             complement(9660..11993)
                     /locus_tag="KRH82_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8656627.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKAISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTMTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(11968..12684)
                     /locus_tag="KRH82_003368"
     CDS             complement(11968..12684)
                     /locus_tag="KRH82_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656628.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
BASE COUNT         4792 a         1794 c         1675 g         4606 t
ORIGIN      
        1 tatgataata agaaattctt caatatgtgt aaggcaaata tatatttcta ttgcaaattt
       61 ttgttattta tgataatata aatatgtttt tagtctttaa atagttatca ttttaaggag
      121 gtgtgcgtag atggcaaaag tatgtagcgt atgtggtaaa ggtaaggttt ctggaaacca
      181 agtatcacac tcaaataaac ataataaaag aacatggtca gctaacttaa gaagcgtaag
      241 agcgattata gatggagctc ctaagagagt aaaagtttgt actagatgtt tacgttctgg
      301 taaaattgaa agagcttagt aaccacgttt aaaagcctac ttccgtaagt aggcttttta
      361 atttaatcat ttttactctt tctcataaat tttaggatta tacttgaaat ccattttggt
      421 aattttattg ttactacttt catcaatact caccccacac tttatagtta aaactatttt
      481 aacaaaaaaa taataatgct ccacatccaa taagtattaa tgcggtaagt gctgaccaaa
      541 tccagccagg aagcaacatt gacagaatta cagccattcc tgttgctaga caaagtattc
      601 ctagcaatac cttagacttg ttatttctca tggaacacct ccacatagaa cctgtatcta
      661 taaatatttt catattcaag tttatgcgac agttttccat tttagaccaa taaacacatt
      721 atgtaatttt aatttttcat actagaatta ttactgaact ccgatataga ttctacaata
      781 tccaaaattc ctttttttct acttaacctt tcaggtccac tatataaaac aactggtata
      841 actttaggaa gtttaaaatt tttatcttct atttcttcaa ggcttttttt cataataaaa
      901 cttttccaaa tttgttctct atacgatttc aatcttggga caatttcagt atccatttct
      961 gtttgaaatt ctaacactat ataatgtgat actttgccgc ttttagaaaa taccttataa
     1021 attatatcaa cttcttttcc tttatattca catataaaag atgtttctaa ctctatattt
     1081 ttaagagtta attcttttgc tattgagaca cttgtaaaat tttgaatcaa acttaaaaaa
     1141 ctttctttat ctgaatacat tcttctgtac tcttctcgtt tttcattgct tctttttaaa
     1201 ttcatacagt tcctcctaga ctatagaccc tctatttttt agtaaagata gtctataaat
     1261 tttatttttt aattttcatt agtgagtatt gacagttgtg tgtaaaatat ccagtaaaga
     1321 tattttttta tatttttatt aaaagatata aatttttata ttttaatgta ttgacattta
     1381 cgttgcgtaa aagtgtatat ttaatttata ggaggtacta cttatggaat atacagttca
     1441 aaaattaagt aaactagctg gtataagtac tagaacactt agatattatg atgaaatagg
     1501 tcttcttaaa ccacttaaaa taaattcttc aggttatcgt atatatggtc aaaatgaagt
     1561 taataaactt caacaaatac ttttttatag agaattagga attaacttag aaaatataaa
     1621 aaacattata aattcaccaa acttcgatag tttaagtgcg ttaaaagaac accataataa
     1681 attactagcc aaaagaaagc aaattgattt actaatagaa aatgtaacta aaactatagc
     1741 tctgaaggag ggaaaataca ctatgacaga tatagaaaaa tttgaaggtt ttaaagaaaa
     1801 gatgattgat gaaaatgaaa aaaattatgg aactgaaatt agagagaaat atggtaaaga
     1861 tattatagat acatcaaaca aaaaacttaa aaatatgtct aagcaagatt atgaaaattg
     1921 gcaaaaccta aatatcgaaa taattagtaa acttaaaaaa gcttttaaaa ctggtgatgc
     1981 ctctagtgaa ctggctcagg aagttgcaaa attacatcat aaatggttga gttacacttg
     2041 gaacacatac tctaaagaag ctcattcctc tctagcacag atgtatgtat atgatgaacg
     2101 ttttacatca tattatgata gagaacaacc tggattagct aagtttttaa gggatgctat
     2161 agtaatatat acaagagata aataatataa aataataaag gtggtgtctc aaaatgaact
     2221 ttttagttca tgagacactc ttttttgtat gaaatcagat atatttttat cattttatca
     2281 atgaaaaaca ggtttctctc tctattttga gacagaatct ttattgtata ataattataa
     2341 tcaatacaaa ataataacaa attatacaaa acttacttat actatttatg ctaaaaacaa
     2401 aaaatatttt attaaagttt ttaaaactta tgtaatataa aaatctatac tatagacttg
     2461 attatggaaa gaaaattatc aaaatcatta caattagata tactatctct aatatcattg
     2521 tcatgaatta tctttaaaag gatatcataa atggagttta tttttatata atcatcttta
     2581 tttatagcca acatcatgat taatttaaca gtagaatctt cactccaata tattggttca
     2641 tccaatatgg aaatacaaat cttagttctt atagagctta attccatagg atgaggtata
     2701 gctaaaaaat catctatatt ggtagaagat aaactttctc tgtaaaatac agattcagca
     2761 aatgatggaa atacaatttc actttgagtt aatttgttgc acatcaactt tataagctca
     2821 tctttatctt tgattttagg attaacaata aataaatttt tatcaaagaa attgtccaaa
     2881 agattactat aaatatggga attattagtg attgacttag atatattctc tatatctttt
     2941 tttaatagtt ttaaatccac taatacaata ggaatactat catgatttaa aggaattgtc
     3001 gatattatta tatctacatc tgacaattca ctagctaaaa attgattaaa tgatagacat
     3061 tgaagtatat ttattttatc atgaaaaact ttgtttaatt gaacctctaa taacctactt
     3121 gaaccatacc ctgaaccaca tactaatact acgtttttac acttaatatt actttgaaaa
     3181 aatctctcta ttccagcacc tatatgcagg gatacatatc caatttcatc ttctgttaaa
     3241 gagtaaatac tatttttaaa aactttttct atagcattta aagttatttc aaatgctaaa
     3301 ggataattac tctttattgt atttataagg ggattcacct tatttaaatt ataagattta
     3361 gaattgagaa ttgatttaaa gtgcagtact aaatcatcaa ataatacact atcatttcta
     3421 aggtcaaaag tatattgatt gttgattact tctaaaattt cttcaacata ctctataatt
     3481 ttagtatcta ccctattgga aacgttatcc aaaagagaac ttttagttat aaaatgatta
     3541 tatagataaa ctctgtctgc ctttgaaata attatagtat atttgctctc aatataatta
     3601 aatatatttt caacagttgt attcgattga aaatctgtta aaacaacatc taaaacatta
     3661 tctaagcagt aaccatcaag tattctactt acagtaatag ctaaatggat aataaagttt
     3721 tttagattaa aatctaggaa attgatatta aatttattaa tttcacttaa cactaccctt
     3781 tgaagctcta ttaaatctac attattaaat aattctattt ctctatctgt aattccaatt
     3841 atatagtttt caaaattcct atttatcata ttattagaaa tacatcttcg aatatctatt
     3901 tccttccctt caactttaac tccataatat ggcttagaaa ctaatattaa attatacttt
     3961 gacaaaatag gctttattct ttttatgtca tttagtattg taaatttact cacatacaag
     4021 ctattagcta aatcttctag ttttatatat gtattgttat agagaatata ttttaaaata
     4081 tattgatttc tttctatagg agaatctggt atttcacttg aatccataat atcatcagat
     4141 attaatgcta gatactgttg gtataatgct aaattaagaa tatctatata atatccttct
     4201 ccttttttta ttttaataat agcaccattt ttctctaaag ttccatttat agaagtaata
     4261 tcatttctta tagttctctc actcactttt aaatgattac ttaaagtttt acaagtaatt
     4321 ttatcatcac tttcatttaa taatttaaac aacgtgagca atctcttgtg cataaatatc
     4381 cccccttata gaatttcttc taaattatac tatttacact aatataatac aattactcta
     4441 ataaaattgt attataataa tttatttcca cttctatatg gaaattagtt attatcataa
     4501 tataaatttc catgtcgaag tggaaattag ttatatttaa tttaattagg ataatgatta
     4561 caatataaat ataagttaag acattatgaa tggagtggaa aaatatatgg tactacaaga
     4621 aaaatatata tttatagata aagacttaaa aagcaaagaa gaagtattaa attttattgc
     4681 agatagtgct tatatactag gtattacaac taataaagag gctcttttaa aagaccttct
     4741 aaaaagagaa aatgaatttc caacaggaat aaaagatgga tttgcgatac ctcatacaaa
     4801 gagtgtaaat gtaaaggaag cttccatact ctatattaaa acaactaacg agttagagtg
     4861 gaaaacttta gatgatagta aggttagata tgtatttagt ttgttagccc cacataaaaa
     4921 tgaaggaaat atacatttga aaactctatc taaattagcc acatgtttaa tggaggatga
     4981 ttttacaagt gaagttaaaa atgctagtga tgcaagtcat ttagtaaaat atataactaa
     5041 taaaatgaag gaggaataat tatgaaaata gtagcaataa catcatgtat agcaggatta
     5101 gcacacacac ctatggcagc aaaagcttta gaacaagctg catcaaaaat gggtcatgaa
     5161 atcaaagtag aacaacaagg tgctatggga cgagtaaata ctataacaaa agaagaagca
     5221 caagatgcgg actttatact tatagcatct gaccaaacta tatctggaat ggaaagattt
     5281 gatggtaaaa aagtgataaa agtcaaaata ggtatagcgt taaaaaaacc agaagctgtc
     5341 ttaacaaagt gtatagaagc tatttcttaa taaaaaaatc tcactctaat atagaatgag
     5401 aaaaatcaaa aattaaaaaa ttgtctaata taattataac atattatcaa aaaatataac
     5461 aaacttatat aggaggatta aaaatgagta aaaaaaataa atctctttta agtgaactta
     5521 agggacactt aatgacaggt atctcatata tgttgccact tgtaataggc tcatctttag
     5581 ttgtagctat cccaaagctt acagctttag cagtgggtat aacaagttta gatgcttata
     5641 aaaatgtatc tggtttttat catattcttt acttaatgga acaagttggt tggactggca
     5701 taggtctatt aaatacggta ttagcaggat ttatagcatt ttcaataggt gagaaaccag
     5761 ctatgggtgc aggttttatt ggtgggctca tagcaagtaa tactaatgca ggattcttag
     5821 gagcagtaat agcaggtttc tttgctgggt atgtttgtaa gtttttaaag aaaaaaatta
     5881 aaatatctgg gtcagcatca ggaatgatgc cacttataat aatgccactt ataacagttg
     5941 gattaactgg ttttttaatg agtgttgtat tagcaggacc tttaggaaac ataaatactt
     6001 cattaaatgc ttgggtagct gaaatgtgtc aaaatggaac aaattcggtg gtattggctt
     6061 taattttagg cgcaatgata ggattcgatt taggtggacc agtaaataaa gcagcttgga
     6121 tggcaggaaa tgcattattg ttagagggaa tctatctacc agcgatattg gtaaactgcg
     6181 caatagttat acctccacta ggatatggtt tagctacatt cataagaaaa tcaaaatttt
     6241 ccaatgcatt agctgaaaca ggaaaaggca atatagttat gggtataatt ggaataacag
     6301 aaggtgcaat tcctttcact ttaacaaatc cattaaaatt agttcctgtt aatatgatag
     6361 gatgcgcttt gggtgtagga ttatcagctt tgttaggtgt acatgctata atgcctccag
     6421 ttggtggatt atatggattt atatcaatag gttctggatg ggcttactta gtaggtgcaa
     6481 tatttggagc tttagtaata gcaatactat caacaacttt agtagacttc aatgaagatg
     6541 aaactacgga aaatatagaa tttgatgaaa tagagttaga tataatgtaa attaaaaact
     6601 taattttaga taattgagaa ttgagtgtac tctcaattct caattaaatt ttgggaggat
     6661 ttttatgaaa aagacaaaag tacatgtagt tccacacagt cattgggata gagaatggta
     6721 ttttacaaca tcaaggtcaa aaatatattt aatgaaagat tttcaagata tattagacat
     6781 attggaagaa aaagaagact ttaaatactt tactatggat gcacaagctt ctctcttaga
     6841 tgattattta aaatggagac ctcaggatga atatagaata agagatttag ttcaaagaag
     6901 aagattagtt attggacctt ggtatactca aacagaccaa ttggttatat caggagaatc
     6961 tataattaga aacctttact atggaataga tagatgcaat gaatttggtg aacctatgag
     7021 ggttggatat gtaccagatt cttttgggca atcagctcaa atgccacaaa tatacagagg
     7081 ttttggaata gatagttcat tattttggcg tggagtttct gatgatatgg tagatacaac
     7141 agagtttata tggaaaggtt ctgatggttc aaaagtatta gcagttcaaa taccatttgg
     7201 ttattactat ggaggtaata taccagaaga tgattcagat ttaaaagaat atttaaaaga
     7261 tataatcgga aaacttaagg ttaaagcttc tactaataac gtatattttc caaatggatt
     7321 tgaccaagca ccaataagaa aaaaccttcc tgatatatta aaaaaagcta atgaaataga
     7381 taatgaaaat gaatacgaaa taagtgatat agaaaactat atagattcag taagaaatga
     7441 aagaaatgaa tttacagagc ttaaaggtga atttttaaat gctaaacata tgagaataca
     7501 caaatccata ttctcctcaa ggtcagacct taaaataatg aataacaaat tagaaaatta
     7561 tattacaaat gtacttgaac cattattaac attaagttat tcacttggaa atgaataccc
     7621 tcatctagtt ataaaagata tatggaaact tatgtttgaa aatgcagctc atgacagcat
     7681 aggttcttgt aatagtgaca caacaaatga ggatgtatac acaagataca aacaagccag
     7741 agatttgagt ataaatttat tagatttgca tatgagactt ataagtactc aaatcaaaaa
     7801 taataatgaa gaaataacat taacagtatt caatggattc ccagaagtca gaaatgaagt
     7861 tgtagaattt gatacttata ttccaggtca agattttgtg ataaagaata aaaatggaga
     7921 aattcttaat tatataataa aagaaaaaga agatattaca aattatatat taactcaaac
     7981 aataagatta aacccaagta aaaaaatata tatacccaaa actgtatata gagcaaaaat
     8041 tgcactttca gtaaaagata taccaccaat gggatatact caactagttt ttgaattgga
     8101 tactaaaaat aaatgtgaaa tagaaacaag taattgcaaa gaaatagaaa acaaatacta
     8161 caaaataaca gccaataaaa atggttcatt agaaatatta gataaagaat ctaataagac
     8221 ttataaaaac caagctgtaa ttgaagataa tggagatgat ggagattcat acaactattc
     8281 tcctccaaga aaagatattt atgtttcatc tttagattct gtatcttcag tagaagtgct
     8341 aaaatcaaac attcaagaag aaatgatact taaatattca ttgaccatac cagcttcact
     8401 ggaagaaagg gctataggta aagtttctgt gaaaatgcca gtaacaatga aaattacctt
     8461 agaacctaaa gaacaaataa ttaagtttaa tgttaatata aaaaataacc aagcactatc
     8521 tcatagagta agagttttat ttaatacaga aatagcatct aagttttcta tagcagatca
     8581 acaatttgga ataatacaaa gaccaacagt attagaaaaa gaccttgcat tgtggaaaag
     8641 agacaattac tcatggcaag aaaaacctat aactatcgaa ccaatgcaaa gttttgttac
     8701 tttagaggat ggacaaagag gaatagcatt aataactggt tgtgtaagag aatatcaaat
     8761 agttggtgat aatttagata caatagcatt aacactattc aggtcatttg gatatatggg
     8821 aagagaaaat ttactttata gaccaggaag agcttctgga gaaaaaataa tagcaacacc
     8881 agatgcacaa ttacttaaag agttaaactt tgactttggt ctttacatat ataacaataa
     8941 atttgatgaa gcaaatgtag ctaatacagc taagagattc ttaacaccta tacaaatata
     9001 tgaatatgct gattttttaa atggtagact tatatttgca ttcaatgacg aaaaacaaat
     9061 atatgaaaat gaatatagtt tgatgaatgt aaataattca aatttcacag taagtgcaat
     9121 aaagaaagaa gaaaaaggag atggaattgt agttagaatc ttcaatggta tgaaaaatga
     9181 ggatgctaag ggaagtctta acatcaataa aaatgtcaat gatgcttata gtgcaatgct
     9241 cgacgaaatc tatgataata ctagcaagct taaagtaaat actaaaactg tagaggtaaa
     9301 ttctttatca cattgtaaag tacaaacaat agtaattaaa taatataaaa tagcttatac
     9361 aagatttcaa aataaattgc tagtactatg ttaatagtaa acccagatat tatgctattt
     9421 ataagctctg taacactaaa taacattttg taaaataaaa aggtgaacct tgtatattag
     9481 gattcacctt ttttaaataa atcaacattc tgttttaaaa taacatttat aagctgtttt
     9541 gaaataatgc ttacaaatta ttttaaaaca atacctataa atttttattt aaagaataca
     9601 cataaatatt tccagactct tttattctat agactttata attattaaat aagtctaatc
     9661 taatttttgt taaaagtaat tgtaacttta aataaatcac catccacact tatattcatc
     9721 ttaccaccct gtaattctat aaaacttttt gctatcgcta aaccaagacc agaaccttct
     9781 gtgttacgtg atttatctcc tcttacaaat ctctccatta tatcatctac actaaaatca
     9841 atctcagatg cagacatatt tttaagcata atatttactt tattatctgt ttctaaaata
     9901 tcaatataca ctcttgaatt tggcattgca tatttgctta tatttattat aagattttca
     9961 aatactctaa atgtacgctg actatctaat ggtaatatta ttttttcatt agaaaagtta
    10021 ttctttacta ttagagatga atctgcaagt ttgtcatcta attctaaaag tgtctgcttc
    10081 attagagata caatatccac atttactata ttcaaataaa catctccact atttgccttg
    10141 cttacttcaa acaaatcttc tattagatgt tgcaatcttt gtgactttct gtctaatgta
    10201 tcaatataca acttacgatt ttcatctgtt atactttcat cttttaataa atctatataa
    10261 gtgattatag atgttagagg tgtttttaag tcatgtgata catttgatat aagctctgtt
    10321 ttcatctttt gactcttaac ctcttcgtca acagcttttt taaatccagt ttgaatattt
    10381 cctaattcgt cttttatagg attaaaaaat cctaaatctt tttccatatt tacatctaag
    10441 tttccatctg aaattttctt tgtaacatct aaaagttgat tatattcata tattgtcttt
    10501 ttagagtaat ctgacagtat cttaaataat actactgaat atattaatgc gagtattatt
    10561 ccaaagaacc acatactaca cattataact ataatcaata aatttattcc caaaattgta
    10621 actatagttt tatttggctt ttcttttaga tttattgttc taatttgatt aataactgtt
    10681 tttcctgctt tttttagcca tacaaaaaac attcctgtca tagtatgttt tgtaaaatac
    10741 tctcttattc caacatttaa aatgtgtttt aaaagtatta taaatacaaa tattattgag
    10801 aatattacaa accaataagt taaattcatt aaacttacca atatgctagc cattttagca
    10861 cttatgtcat tgtttataag gtactctaca taattcccac tcaaggtatt acttattata
    10921 acagtaggat ataaatctac aagcccctgt ataatagcaa gagcaataaa gagtatctct
    10981 aacggtattc ttgataatgt atcaaatcct agcaactctt tagattttct atatgggaat
    11041 gctaaagcta caataacaac tatagctaat ataattttta aaatcattcc agaaatctta
    11101 taataagaat tattttctac attgcttata tatgaaatta taccatcatc aaaataagta
    11161 tttccataac catactctac actatcacct ttacttattg ctttaggtac agcatatact
    11221 aatgttatat tttttattgg agataactta tatgaaattg aatttcctcc taaacttgta
    11281 tccattaaat cttctcttgc tttagataac aacatttgat taataacttt ttgatttact
    11341 ccataagaat ctacaatatt tacttttcca tctttatcaa aattcattac aacgtagaat
    11401 ctatagtttt cttttatatc tgtaatctgc ttttgtcttt cctcatcatt catttctgta
    11461 ttttttgact gattttcatc agaattttct tttgaagcat cattctttgt tgtatcaagt
    11521 actcctaatt ctttattatc attaaaaaat tcaaaattgc tttctttatc aactaaatag
    11581 tactttaaat tctttcctga cgctttaatg aaatgctccc aattttcaaa gttttcatta
    11641 aaatctgcat taatactatc atctgtatag taagtttctg aaccatcata agtatctttt
    11701 tctttactta cattttttat atagttcata gtttcttcat tgataaatag ctttgatggt
    11761 tgtatcatct taccttcttg ttcttccttc atattatgat ataaaacata acttccttta
    11821 tatatactat ctacaaagct ttcctgttca aatggattct ctgctccacc tttagcactt
    11881 gcttgtatag tagaatattg actaatcata cctaatgatg ctgataacat aagtataaaa
    11941 actataatag taactatata tttatcttta aattttttca attttgtatc caacacccca
    12001 caccaccttt aaatatttag gattttttgg gtcaatttct atcttttccc ttatattcct
    12061 cacatgtacc ataactgtat ctgtatttac agcattctca ttccaaactc tttcatatat
    12121 ttcatcagca gaaaaaactc ttcctgcatt tctcataagt aaacttagta ttttaaattc
    12181 tataggagtt gtttttatat actttccatc aatactaact tcttttgtat tttcatttaa
    12241 ttctaatccg cctattgcaa acacactatc gtcactttct accttttgct ctttatttcc
    12301 aaccatgttt agatacttag tgtaccttct aagttgtgaa ttaactctag ccaatagttc
    12361 taatggctta aaaggttttg ttacataatc gtctgctcct atattaagcc ccattatttt
    12421 gtcaacttcc tctgattttg cagatagcat tattactgga aaattatagt tttctctaag
    12481 cttcattgta agtgttatac catccatttt aggcatcatt atatcaacta tagctaaatg
    12541 tatttcttgg ttttctataa ccttaagacc ttctaatcca ttgtatccct taaaaacatt
    12601 atatccttga tttaatagat atatttctat agcatctgct atctcctttt catcttctac
    12661 caccaaaata ttatatgaat tcattctaat ctcctttata ttaatttata aattttcttt
    12721 acatatatga ttatacaata tgatagaagt ttttccattt atatatatat ttatatcttt
    12781 tgttctggtt atttgtattt aatgtccatc ttagaaacct ccttctagtt taaatttaat
    12841 attttttcat tttgttttat atactta
//
LOCUS       DAEOTL010000103        12756 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEOTL010000103 DAEOTL010000000
VERSION     DAEOTL010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.104"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..618
                     /locus_tag="KRH82_003369"
     CDS             <1..618
                     /locus_tag="KRH82_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008819588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore surface glycoprotein BclB"
                     /protein_id="HBG8656629.1"
                     /translation="ADGATGPTGATGATGVTGATGPTGATGATGATGASAIIPFASGI
                     PLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAAGTLTNFAFSMPRDGTITS
                     ISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGATVTLAPPLTGILSVGSIS
                     SGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASAGIAIN"
     gene            787..1548
                     /locus_tag="KRH82_003370"
     CDS             787..1548
                     /locus_tag="KRH82_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBG8656630.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            1857..2135
                     /locus_tag="KRH82_003371"
     CDS             1857..2135
                     /locus_tag="KRH82_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656631.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            2428..3003
                     /locus_tag="KRH82_003372"
     CDS             2428..3003
                     /locus_tag="KRH82_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBG8656632.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            3442..4152
                     /locus_tag="KRH82_003373"
     CDS             3442..4152
                     /locus_tag="KRH82_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656633.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            4146..5462
                     /locus_tag="KRH82_003374"
     CDS             4146..5462
                     /locus_tag="KRH82_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBG8656634.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDNKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            5474..5614
                     /locus_tag="KRH82_003375"
     CDS             5474..5614
                     /locus_tag="KRH82_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBG8656635.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            5673..6250
                     /locus_tag="KRH82_003376"
                     /pseudo
     CDS             5673..6250
                     /locus_tag="KRH82_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
     gene            6507..6881
                     /locus_tag="KRH82_003377"
     CDS             6507..6881
                     /locus_tag="KRH82_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656636.1"
                     /translation="MNLKKKIKKLGVTFAIGTIIVSSLGTSVFADEVSTYALISKAFS
                     GKNNIISSSVYTSGSRTFKTTDSQGGFSCRLTERFSGSSPDRIVKRHEANASSKVSLS
                     GGTYYIRYEGSTNNAKTYATLN"
     gene            6964..8673
                     /locus_tag="KRH82_003378"
     CDS             6964..8673
                     /locus_tag="KRH82_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656637.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITVIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNIKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSYMAYKINLSSKSNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            8688..9560
                     /locus_tag="KRH82_003379"
     CDS             8688..9560
                     /locus_tag="KRH82_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8656638.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            9561..10349
                     /locus_tag="KRH82_003380"
     CDS             9561..10349
                     /locus_tag="KRH82_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656639.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(10445..11083)
                     /locus_tag="KRH82_003381"
     CDS             complement(10445..11083)
                     /locus_tag="KRH82_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBG8656640.1"
                     /translation="MIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGYASDIRMQ
                     KTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLNKESKLDK
                     AVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNCAKKNNRFL
                     EALKILESKMIGNKIVVESVVPKLSKLSFCKKGESSEIAKTHYYEILKNLEK"
     gene            complement(11110..11739)
                     /locus_tag="KRH82_003382"
     CDS             complement(11110..11739)
                     /locus_tag="KRH82_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBG8656641.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPNGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMV
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            12050..12709
                     /gene="cprR"
                     /locus_tag="KRH82_003383"
     CDS             12050..12709
                     /gene="cprR"
                     /locus_tag="KRH82_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBG8656642.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
BASE COUNT         5110 a         1253 c         1969 g         4424 t
ORIGIN      
        1 gcagatggag caacaggtcc aacaggagca acaggggcaa caggagttac aggagcaaca
       61 ggcccaacag gagcaacagg agcaacagga gcaacaggtg ctagtgcaat aatacctttt
      121 gcatcaggta taccactatc acttacaact atagctggag gattagtagg tacacctgga
      181 tttgttggat ttggtagttc agctccagga ttaagtatag ttggtggagt aatagacctt
      241 acaaacgcag caggaacatt gactaacttt gcattttcaa tgccaagaga tggaacaata
      301 acatctattt cagcatactt cagtacaaca gcagcacttt cacttgttgg ttcaacaatt
      361 acaattacag caacacttta ccaatctact gcaccaaata actcatttac agctgtacca
      421 ggagcgacag ttacactagc tccaccactt acaggtatat tatcagttgg ttcaatttct
      481 agtggaattg taacaggatt aaatatagca gcaacagcgc aaactcgatt cttactagta
      541 tttactgcaa cagcttcagg tctttcatta gttaatactg tagcaggata tgcaagtgca
      601 ggaattgcaa taaattagat tagataagaa aaggcttcta atatcgtatt gatattagga
      661 gcttttttaa gaatgattga tgaacatagt tttaatatta attagtgcgc atattataaa
      721 atactattat ataatataaa ataataacat taaattggaa atatagaatt atctaggggt
      781 gatactatga aaaataagat tgaaatatca atgaacaact ttgtaaaaaa ttatcataaa
      841 tcaaataata taactacaaa gtggcaagaa cttttgtttg cttatgcatc tgctgaagat
      901 gatatgtttc agaagctaaa aagtgttgta ggaacatctc atgctatgcc aaaagatttt
      961 ctggaaaatg gaaaaactat aattacatat tttatacctt ttgatgaaag tgtaaataat
     1021 agtaatattg gagggtttga atgttctgaa atatgggcaa gagcgtacat agaaactaat
     1081 atgttgattt caaatttaaa tgatttctta tgtgaagaac tagagaagat aggggctaat
     1141 tcatatgcta ttcctgggtc gtataatttt gacagtgaaa aattggtaag tgactggtca
     1201 caaagacatg tagcattcat agcaggtctt ggaacttttg gtttaaataa tatgcttatt
     1261 acagaaaaag ggtgttgtgg aagaatagga agcataatca caagtttaga attagagcca
     1321 actaaaagac cagaaaatga atactgcttg tataaacata ataatagttg caaaaaatgt
     1381 gtcaataaat gcgtgaaaga agctttaaaa gaagatggat ttaataggaa taagtgttat
     1441 gaaatgtgta tgataaatga aaaaaaatac acttatatag gtggatgtga tatttgtgga
     1501 aagtgtatag ttggagttcc ttgttcagta ataaacccat caagataatg gacttaagtt
     1561 gactaataat tttaaagata gtttataatg aaaaaatttt agttatcaaa ataaatataa
     1621 tataaaaact aaataaatgt gtttaaaaaa tggataaata atttgtgttg attgacaacc
     1681 agttatactg ttgatagact tatatgtatc gctgtgatat ataaggaggg ttgagatttt
     1741 atgtttgatt taatctttat ttttgcatag caagggctat tgcaactatg aaatttaata
     1801 tataaatagc cctttgctat tcctaatgaa aaattactat ttaataggag agcaaaatga
     1861 gctataaaaa agcaatacat atattaccag aagaattact tgaattaata caggaatatg
     1921 tagatggtga atgtatctat attcctagaa aatctaataa taaaaaagaa tggggaagta
     1981 atacacctac tcgtgaagag ttgtcaatta gaaatatgca gatttacgaa gactatcaag
     2041 ttggatatga tttgcaatat ttatcggaaa agtattattt atctttgaaa agtatccaaa
     2101 gaattgtatt acaagaaaaa agaaaagata tctaaggatg agccagtata gttttataat
     2161 tatactggct cattttcttt tgataaaagt gtttgaggta tagtttcttt taagtggatg
     2221 atataattta agtaatttca ataacttata cagtagctaa caaagctggt tgtaaagtat
     2281 ctaataagaa gtagtagctt tttatatgtt tgaaattaaa atttattaaa attaggaggt
     2341 cttgttttga aaaaaatact tgattatatt ccaccttttc ataactttct attaatttag
     2401 taatcttata gaaaggaaat tgcatttatg aaaaaaatta cttgggaggt ggaatatatc
     2461 tcccagttac ctgtaattag gtattgtaaa aaatgtggaa aaaagactga atatatttgt
     2521 tcaggtttat ttagggttaa tgctcaacat aaatatttgg atatatggtt aatatacaag
     2581 tgttcaaatt gtgattcaac atggaactca actatatatt ctcgtgttaa tccaaaaagc
     2641 ttaaatccag aaatactaga acaattccat acaaatgatt ataatcttgt taagcaatat
     2701 gctatgaata tggaactttt acatagaaat ggagcagaag ttggtattcc agagtataaa
     2761 atagtaggac aagaaattaa tattaatgac cttacacaag ttcatattat tagtaaatat
     2821 ccatgtcagt taaaggtatc aacattatta cgtgagaaac taggtttatc taggaaggta
     2881 tttgacgaaa tgttggattg tgggattatt agaagtaact caggagttga tttaaagaaa
     2941 ggtaaattaa attatgaaat tatgttagat ataggcaagg agaagcaaaa gtcttcaaat
     3001 tgattagaat aactaactta atatattttc aggaacatca tttaaaaaaa tagtgacttt
     3061 aaaaaattta aagccactat tttttaatat gttttatatg agtatttaaa ataaagtgtg
     3121 tattcttcaa atttatagcg ataattaaaa cattactata aaaaggaagg tgcatacttt
     3181 ttatttaaca aaaactagat attaaaaact tttcgaggaa tattttatta aaatccctaa
     3241 atatatttaa tatatattaa aaaattgtat tataatgaaa atcaaaatag attgcaaatc
     3301 caaaaagtaa tacttaatgt ccaaaaagct aaaattaaaa tctaaatagc tatttactac
     3361 agaagtatgt taaaatatgt aaaatgaata gaaatttata tatttttatt aaaaatatat
     3421 aagaaaggat gtttaagaat tgtgattaat ataggaatat gtgatgatga actacattat
     3481 cgaataaaaa taaaagatat attaagtgaa atattaagtt catatcctat aaattataac
     3541 atatatgaat tttcagcagg agaagagtta ctaaataact atcctaaaga tttagacata
     3601 ttaattatgg acatacaaat gaaaacaata aatggtatgg atactgctag gaagataaga
     3661 gagtttgatc ataagttaga aataatattt gttacttcat ttgtagagtt tatgcaagaa
     3721 ggttatgagg taaaagcata cagatatata ctaaagccaa taaataaaga aaaaatttct
     3781 aaaagtgtat taccttgtat aaatgagatg atgaaaaaga gaaataatta cttaactata
     3841 aatgtaaaaa attatgtaga ccgaattaaa atagattcta ttacttatat agaaacagat
     3901 agaccgaata tattgattta tacacatgat gatatgtata ttactaaaat gagtatatct
     3961 aaaatagaaa agatattaaa tgaatatgga ttttttagat gtcataatag ctatatagtt
     4021 aacttaaaat tagtagaatc aatgagtgga agtactgtta tagtagatgg aaaaagtatt
     4081 ccaataagta aatatagggt taaaggcttg aagcttgcga taactaatat attaggggac
     4141 atagtatgct aacaaattta agtgtaggat tttggaatat tattaattta gtttcaggta
     4201 ctatagattg gattatattt tttttagtaa tccacttagt tggaaagagg aaaatatcta
     4261 atataagata tatatttaca acaataatta taattatatt tatggcatac ataaatgtag
     4321 ttaaagtgtt tccaaatatt aagattcttc tatgtatggt aataggaata tcattttata
     4381 taacatcata tgaagataaa atctataaaa gtataatagt tagtttattg ttttggctag
     4441 gattaatggt tgctgaaggt tctgcagtag gtctagtagt atttataaat aaattaaata
     4501 atattaacat aacacaacat gaaaacttat ttagaataca agctattatt atgtcaaagg
     4561 tatttttatt tataggtttt atattgttta agtattttaa attatcttta gattttaaac
     4621 ctaaagatat gatactaata ggaataccta tattatctaa tatagttagc ttattactta
     4681 tatttgaata taatttaaga gtcaatacaa ttactacaga aaacttattt atatttatat
     4741 ttgcaatttt attgatttta tcatcaagta taatactttt aatagtaata gggaaaattg
     4801 tacaagacga taaattaaat ctagagtatg aacttataaa tgaaagaata aaaacaaact
     4861 acaggaatta tgaaaatata aacgaagttc atgatagatt aaaatatgtt tatcatgact
     4921 tgaaaaacca tatgatttgt ataaaaaatt atgacactaa agaagaaatt atatcatata
     4981 taaataactt agagtttcag ataagtgaat ttgaacattt taaaaatact ggaaataaaa
     5041 cattagattt aattttagca gaaaaaataa gtatttgtaa aaagtatgat attcaaattg
     5101 aagataacat aaatatatct aaattaaact ttattaaaaa taatgatata tgttcaatat
     5161 ttgcaaattc actagataat gcaattgaag catgtatgga tataaataat gagatagaaa
     5221 aaagaataga agttaaagct acatatataa ataaatttgc aataataaaa tttataaata
     5281 ctaaggtaaa tgatattaaa cttattgata aacgtattca aactagtaag gatgataata
     5341 agatacatgg aataggactt gctagtatta aatatatagt aaataaatat ggtggtgaaa
     5401 caatagttaa ttactcagat aatgagttta tattaaaaat aatgatacca ataaaaagtt
     5461 aggagagtac aaaatgaaaa aaatagcgtt aaacttactt aaaaacatct cagcattaag
     5521 ttttgggata gctgtattat cagcaaacag tgcaagttct tgggtagcac atcaggcaaa
     5581 agagccacaa gctttacaaa aactaaaaaa ataacattaa taaaaggacc tcttcttatt
     5641 aaaggagagg ttttacatgt tgaggaggaa atatgtttaa aagattatca tataaatttg
     5701 ccaatatatt agttaataat gagattgtag aaagtgaaga ttttgaaata tatagatatg
     5761 gatttgaaac tttgatttat ttcatagtta atattttggt agcattattt ataggaatta
     5821 tttttgatag atttatacat acagttatat ttttaagttg ttattgcact ttaagacagt
     5881 tcacaggagg ttatcatgct aggaattata aagagtgtac attaacattt gcagttattt
     5941 atttgataac tattttttca gctaataata tagatataaa tataagtatt tattagtatt
     6001 attaatgatt attagtatac taacaattta caagttagct cctttagaac atagaaacaa
     6061 acctcttagt gaaagtgaga aaaagcatta tagaaagact gtgcaaaaaa tactattcgt
     6121 aataatatgt ttaattattt tatgtaaaat acttaatatt tttcagcaat atatgattta
     6181 tgcaataatt tctatatatt ggattgctat attaatatat attggaatga aggttaatag
     6241 tgatcagtaa gattataaaa cattttctaa attaattaac ttcactaatt aatattaact
     6301 ttaaaaaaat aatgtcaagg taagtatttg aacttattaa atatagttga atctattgtg
     6361 ggttgtatca aaggacaaat agattcactt aataaccagt ttgtaacaga gtattgaatt
     6421 gtaaaagtta atacgatagt atgaaaatgt aatttgaaat tacattttta taaaaattat
     6481 attaactaag gggagggata catacaatga atttgaagaa aaaaattaaa aagttaggag
     6541 ttacatttgc aataggaact ataattgtat caagtttagg gacatctgta tttgcagatg
     6601 aggttagcac atatgcttta atatctaaag ctttttcagg taaaaacaat attatatcta
     6661 gttcagtata cacttctgga agtagaacct ttaaaacgac agattctcaa gggggatttt
     6721 cttgtaggct aacagaaaga ttctcaggat ctagcccaga tagaattgta aaaagacatg
     6781 aagcaaatgc ttcttcaaaa gttagtttat caggaggaac atactatata aggtatgaag
     6841 gttcaacgaa taatgctaaa acatatgcaa ctttaaatta gtattaaaag catcctataa
     6901 ttatttttat aggatgtttt tgtaattgtt ataatcaaaa gactggctag gaggggcata
     6961 aatatgagta gtattaaggt tatatcagac tttataacca aaataattag aaaaaatatt
     7021 ttatttgcaa taacagttat tattataaat taccatctca tacaacgatg gacacatata
     7081 tccaatagag gaatttcatt taatgattac ttatccttga gtgtatatac ttgtatgaca
     7141 attagtattt taaccatgtt aaatgtaatt ttttatatga gaaaaagtta tgatactgta
     7201 aaaatattat gtagaaataa ttttgattat tttttaggta tttctgttgc tgtaactaga
     7261 aacaacttta tattttgttg cataccaatt atatatgcta tagcatactc aagtttaata
     7321 agaacattgt caattgtaac gattaaatca actatattta tattgatatt tgaatggttt
     7381 ttaccactta ctattttatc tatagtgata tcatttattt cagttattat aaataattta
     7441 atactaaaga ttaccttatc atcagtattt ttatatttaa catcaactaa tatgttggat
     7501 agagttattg atattaaaga accatttttt aaagcattat ttaaatcact taacatattt
     7561 gaagatcaat catatgctta ctattctgat tttgtaggga aagttaataa ttcagcatat
     7621 gttatagata agattatacc tacactattt gcaattactt taataatagt agcatatctg
     7681 atattaaatg atattagaaa gaaacagatt aaatcattaa tagttatagt agtgtacagt
     7741 attttattta ttggattaaa ttatatatca atagatatgt caacatatag agatgaggag
     7801 cgtagttatg gagagtattt aaagaaatct aatattagtg atattaaaat aaaatcgcat
     7861 gatatgaaga ttgactttaa aagcaagtca aatataaaag atagaattgt tttattaaac
     7921 acatcaaatg aagagttaac aaatattaat atgattttag atgaaatatt tgatataaaa
     7981 tatataaaag taaattcgga aaatataaaa tttaacataa aaaaggattt aattgaagtt
     8041 aatttaaagg aaagtttaga gcctaatgac gaggtgacat tagatataga gtatgaaggc
     8101 tatattaatg tgttgacatc ttggaatcaa aataaatata tagctactaa agatgatatt
     8161 atgcttccac caggttcttt agcgtggtac ccaaaagtaa atcaatcaag ttatatggct
     8221 tataaaataa atttaagttc taaaagtaat gtctattcaa atttaccttt actgaataag
     8281 actagtaatt ttttaaaaaa agattatata tttgaaggaa agtcaaatga tattgcaata
     8341 tatgcaggtg agtttaaaga agaggtaaaa gatgatataa aaataatcta tccatcagat
     8401 agtaatgtaa atatggatat agaggaaaaa attaaatttt taattgaaac aagaaatgaa
     8461 atattaggtg atagcaaagc atctgtagat gctaaaaaat atgtagatga agtagataat
     8521 gttatggaat caataaaaag aaaaaaaatt aatatgatat tagttgctga cttacctagc
     8581 aatgaatttt tatatgaaga ctcaaaggga gagaaaatta gcataactat ttatcattgg
     8641 ctttcaggaa atatccttat aatagataaa taataaagga ggttaatatg ataaacaagt
     8701 tagaaataag aaatctaaat tttaattaca aaaataaaaa agctttggat aatataaatt
     8761 taaccctaac agatggagta gttgcattat taggtcctaa tggtgctgga aaatcaacat
     8821 taatgaggtt attagtgact ctttatgaaa cttcaattgg agagatagaa ttaaataata
     8881 taaagtatag caaaaacaat gagaaaatca aggcaaatgt aggatatgta cctcaagatt
     8941 ttgatatgta taataatata aatgggcaag aatacttaga atttgtagct aaaatgagag
     9001 gtgtatctaa gaatgattta aagaaacata tacaaaaagt agtatcaaaa gttaatctgg
     9061 acaagtttat aaataaaaaa ataggtacat actcaggtgg tgtaaagaga cgactaggta
     9121 tagcacaggc tttaataggt gattctaagt taatagttat ggacgaacct acagttggtc
     9181 ttgatccaga gcaaaggaat gaatttagaa gattgttacc agaaataagt aaaaattcta
     9241 tagtattaat ttcaactcac atagtagaag acatacaatt taactgtgac aaattaatta
     9301 tattaaatca aggcaaaata ttatatgatg gtacaattaa taagtttatt gatatggttg
     9361 aggtgtattc ggtagtagtt tctaatgatg aatttgaata tttagaacgt aatattgata
     9421 ttattgatta taggagagtt aaagatggtg tgcaagtaaa gtatataggt aaaaatacag
     9481 agaaacttaa agatagctta aggatagata caactttaca agatgcttat ataaactttt
     9541 tacataagga gttaaaataa atgtgtatat tggagttaat aaaatttgag cttaaaaaaa
     9601 tagagcttaa acatgtgtta atatttgtaa ttatttctat attatgcata tttattacag
     9661 gcatattaga ttataatgag ttaatatttt ataatgatgt acctataatg gatacatatt
     9721 ctatagcagg atggttagga attataaaga tatcagatgt ttttatacca ataatgtcag
     9781 caatcacaat aatttatgtg ttttcaaaag attattcggg taatataaat gagatactta
     9841 ctttatataa taaaaaaaaa tataatcaat ttatagtatt tagatggtgt gttatattag
     9901 ctatatatac tgtattatta ttaatttcaa ttacaatagt atatacattt acgtcagtga
     9961 aaggttttaa catagacaaa atagattttg tttatagtgt aaagccaata gatgtgtttt
    10021 taaagacgtt tcctacatta ttatggtata caacatttcc actaatgata ttaacattaa
    10081 caaaaaatag atttacaaca atagcaatat taattacata tacatttgct gatatatttt
    10141 ttattttaca tatgtaccca tttgttagta tgattaatgt aaatggattt tatattcaaa
    10201 agatgtttta tatgcctaac aatatagatg ttagatttaa tgaattaaag aattatttct
    10261 ttataaatag aggttctcta gtagttattt ctataataat agttttttat atagcaagaa
    10321 aatcaacggt tttaaaaaag agtaaatagt ttaatatatt ttttatattg ttatatttat
    10381 atagaatagt gactttaaaa aatttaaagc cactattttt taatatgttt tatctatata
    10441 actattattt ttctaggttt tttaatattt cgtaatagtg tgttttggct atttcacttg
    10501 actcgccttt tttacaaaaa gataatttgg atagttttgg aactacactt tcaacgacaa
    10561 ttttattacc tatcatttta gattcaagta tcttcaatgc ttctaaaaat ctattattct
    10621 tttttgcaca attataaaat gataaaacgt agacataaag gaataggtta taattacgga
    10681 aaggatattc aacttgcata aataaggttc caattccata gtgacaaggg ccgattggtt
    10741 ttttaatagt ccaatggtca agtagaaaat ctacagcttt gtcaagtttt gattctttat
    10801 ttagataatt actaaaacgg aatgcattta atatattaag agttggtagt ggatttgagt
    10861 attcagtttc tggacctcga ccaaaactaa atttattgca acgccaccca ccatcagtat
    10921 actgtgtatc taaaaaatgt tgaaacgttt tttgcattct aatgtcagat gcatatccca
    10981 tatgacagag tacgttagca gcatttgcag tatgacaagg gtaaatacct ccatttggat
    11041 atagtttgaa acgtccatct tctcgccatg tgctaaatat caaaaacttt attataatat
    11101 tatttatatt tataattgat ttattttatt taaaattgca tttatagctg tatcaggaac
    11161 aactgctaaa tcttctgcat tgaagtaata aactatatta gaatcaaata atatatttga
    11221 atttggagga aattcatcat ctccaaacca aagtataaat accatagatg tattacccat
    11281 atatgtaaac ctataagcta aatctcccat gtttactttt tcagctccaa ttttctccat
    11341 aactaactta tatttgtcta tttgagatgt aaaaacttct gaaagcctat atagagtcct
    11401 gtttaaaaaa tttggataat aaacattgcc tcctggtatt tctttaaaag ttacatattt
    11461 attagttcta ggaatacctt tagcattgat taaatatcta actatcaaga ttttaagctc
    11521 aaagttattg caaaggctac cattactatt ccaaacttct ccatttggat agtctataat
    11581 atattgtcta tcaaaaaaat tgagtgtgaa tctatttaaa tcattattga aaggtatatt
    11641 acttaaatta ctaattgtat gagggtctaa ttctttgagt ttttttcgaa catagtcaaa
    11701 tggaacatta taattatttt ttgttatctt ttcatccata attttttcct ccaatttaaa
    11761 caattaaaag tatatttata aaaagttttc ttattattaa ttttattata tattcaaaat
    11821 attacaataa taaattgtta aataaatttt tatatttaag taaatacgtg taaaatgaat
    11881 ataaagtttt tgaaatataa agtttttgta tctaaaatat tttatttgta aaatagtaat
    11941 taattattgt aagctataat ataagagtat tatggttaat gtgaatttta aagatattat
    12001 taaatatata aattagaatg ctattagatg gataaatgga ggagttatta tgtctaagat
    12061 attagtagta gatgatgagt tagatatgtt aaagttgatt gaaaatgtgt tgaaaagaga
    12121 tggacatgaa gtaaaggtaa ttagtgatgt agaaaaggct atgaacatgg attttaatta
    12181 ttttaatcta ataatattag atgttatgat gcctaagatg gatggttttg aagtatgtaa
    12241 aactataaga aataaggttg attgtccaat actgtttttg acagcaaaaa atatggaaag
    12301 tgatattatg tacggtcttg gtataggtgc agatgactat ataaccaaac cttttggtgt
    12361 aggagaatta agggctagga taactgctca tttaaggcga gaaagtagag aaaaaaagaa
    12421 tttattaact atctcaaatg ttcaatttaa ctttttaggc aaagaagttt caattgatgg
    12481 taaaaaaatt aattttacta aaagtgaata tctaatatgt gaatttctag caaaaaataa
    12541 gggacaagta ttttcaaaag aaagaatata tgagtcggta tatggttttg atggagaaag
    12601 tgatataagt actatcacag agcatataaa aaatatacga agcaaattaa aacaatatga
    12661 tatttataca atagaaactg tatgggggat agggtataaa tgggtgtaat aagtataagt
    12721 gttgtttagt gaaaatatta tatatatcta caaaat
//
LOCUS       DAEOTL010000104        12453 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEOTL010000104 DAEOTL010000000
VERSION     DAEOTL010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12453
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.105"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(91..378)
                     /locus_tag="KRH82_003384"
     CDS             complement(91..378)
                     /locus_tag="KRH82_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656643.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(398..673)
                     /locus_tag="KRH82_003385"
     CDS             complement(398..673)
                     /locus_tag="KRH82_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656644.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(1310..1489)
                     /locus_tag="KRH82_003386"
     CDS             complement(1310..1489)
                     /locus_tag="KRH82_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656645.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGHAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(1774..3240)
                     /locus_tag="KRH82_003387"
     CDS             complement(1774..3240)
                     /locus_tag="KRH82_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656646.1"
                     /translation="MKRKPQYLIIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLLTYM
                     YKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIGDCL
                     PSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYINTEEGAK
                     RLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDFVLL
                     CKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYLKKG
                     DVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            4228..5406
                     /locus_tag="KRH82_003388"
     CDS             4228..5406
                     /locus_tag="KRH82_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8656647.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYRLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHHRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYINNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
     gene            5756..6637
                     /locus_tag="KRH82_003389"
     CDS             5756..6637
                     /locus_tag="KRH82_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBG8656648.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESIKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            6828..6995
                     /locus_tag="KRH82_003390"
                     /pseudo
     CDS             6828..6995
                     /locus_tag="KRH82_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(7255..9822)
                     /locus_tag="KRH82_003391"
     CDS             complement(7255..9822)
                     /locus_tag="KRH82_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBG8656649.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSNP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(9825..10430)
                     /locus_tag="KRH82_003392"
     CDS             complement(9825..10430)
                     /locus_tag="KRH82_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8656650.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(10804..12264)
                     /locus_tag="KRH82_003393"
     CDS             complement(10804..12264)
                     /locus_tag="KRH82_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBG8656651.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
BASE COUNT         4241 a         2133 c         1569 g         4510 t
ORIGIN      
        1 agttcaacta tactggttta aataggtttc ctttagttta aataattcac ctatacctac
       61 ttgaatagtt cacttttatt tgcttaaatt ctataccaat actggcttaa acattatact
      121 accatgattg tattgtctat cttcaactac aataaaaaca ggttctaaat ctttagtaga
      181 tgttattttt aattctaaaa aaacattatc agttggtaat atttttacat cataattatt
      241 taaattatta ttcgtgatac tattaaatac atcaccttga cgttcaaaaa aaacattatc
      301 aactattaca aaataaacat cttcttttct actattttca acctctatag tattttgttt
      361 agttacattt agtctcatct tccacctcct attaatatta cttaattata ttaatacttg
      421 taattgttgc attatgttca tcacaaggaa gaggtttaaa aacaactatc tctgctaaat
      481 aattctgtgg aggatttgta actgaagtag cattgcaaat aaatttaaaa tttgttcctg
      541 ctacaacttg agtagaaaca ataagtggtt cataaccaac cccttctaac attcctacag
      601 cttcattaaa tacttttaaa tcttcttctt cgacagctct gaattttgac catccaccaa
      661 caaaaagact catataaaaa cctcctttat atatatattt atttatatat atagtagtac
      721 caattttctc aatattcaat attttctgtg taactggtca atgaaaatgc ataactggat
      781 aaaaatactt ataaaataac ttaactttac atataaatag cttactttac atgtaataag
      841 attattctac aatatgaaat gcatcttgtt ttgaatatat tctaaataca ataatggata
      901 ttttcaatta ttataattag aaaatatcca ttacttaact tgttttattt aaaatcacat
      961 agagacttta ttattttttt tattgcatga atagctattt caggtatcat aagttgatat
     1021 accccctcct tgaaaccaca aaaaacataa caaactttac gaatcttgtc ttaaaagacc
     1081 acaggtacat tccttatttg tggattggag tagccataac aagcaaattt tacaattttt
     1141 atgatgacaa aaatcaataa aatcgcttag tatataacac gaaacactac ttgttactat
     1201 taagaatagt tagataggaa gtatgcatta taccaataaa ggaatcaata aagaaagtta
     1261 aaacatccct acaaatcaaa aatctgttac atttttctat atttaaacgt tatttactta
     1321 caattggaga aataacaggt tttccttctc ggtcaagtaa aggcgtaaat ccggctgcat
     1381 ggccataata gtggaataca tagttcacac ctgtttcttt atccacccaa atctccgttg
     1441 catttatttt tccttgtgaa tatacttttt caaatctatc ttttcccatt ttataatcct
     1501 ccatattttt gattggtcta tgccttcttc acttaagtag aaaaaataca taacttattt
     1561 ttttaattct aatatgagca cgtaaaaatg tcaaacagct tatttaattt cataacttca
     1621 tgttactgtt cgtaaccttg tctgtttact tacactgcat tacagcacca ttttatcctt
     1681 tacattattg tattgcacac agtaaaaatg cttactttat gggatttttc aactaaaaaa
     1741 aggattttat ctccacaaaa catttactat ttgttacaat atacctaatt ttaatctcat
     1801 atcaacattt aatgaagata taaccttttt caaatattgt aaagactcct taaaaatatt
     1861 agaaaaagat tctgcaaatc tctcaacatc tccttttttt aaatacctaa gtatctcaaa
     1921 acatacatca aaacgtgttt tcaaaatttc attatattct tcatgaaaaa atctctctaa
     1981 atagattcca aatatcatat attgttttaa atgcaaaaat gtttcctgta atacataaat
     2041 ttgtgtataa tctactatct tacaaagtaa aacaaaatct ggataaacct tacactcttc
     2101 acaattattt tgtaagtacc ttaaatgagt ttctatttta tctacagcta tcaaatccat
     2161 tttatttcct agtaaaagta ctacatcctc aagagtaatc gtaacaaact ccatagcatc
     2221 caaaagcaaa ctcaaccttt tagctccttc ttctgtattt atataatcat catcatattc
     2281 agaaaaaagt gttacatatg ttcccttgcc attaattgtt ttagcaattc ccaattcatt
     2341 tagctcatta taggcacttc taactgttgg aagagataca ttatatctat taattatcga
     2401 agtaattgat ggtagacaat ctcctatttt aatattgcct tcaaaaattt gacaaattac
     2461 atctgaaaca attaagtcat ataaataaca tttttccaac gttacagaat taaaactact
     2521 tgtatctata ctttgtggag cacgattttc taccatttta agtatggatt ctctacaagc
     2581 tttatacata tatgttaata gttttttaaa ttcaattaga ttcccgtcca atccatataa
     2641 gtaagttttt cttacctgct ctatgtattt attacgaaaa aagtctatac aacaattatc
     2701 caagttatcg aaattatagg ccaattgtga aataatgaca tcatgctgaa taatctcaca
     2761 aaaatggtga atcaggaaat tatttgtttt acttattagt ttatttatat attttagcct
     2821 ttgttcttta aagactaaat aattagaact atttttttcc atacaatcga taatctcgtt
     2881 taattcttca aagtctttag atgtaaatct tttaatattg tacatagcaa tagaaggaaa
     2941 tattaaacta aaaatcttat atatttctga tatttgtaaa atcttctcat ataataagtc
     3001 agattctatt gattgtttac tcgtactctg gattaaaact ggtctagaac cagcttttgt
     3061 ctctataaag cccttttctg agagcatttt tattacagtt tttatagtat tttttgatac
     3121 catatattct tctgacatgc tttttataga atcaagccta tctccaatag taattttacc
     3181 agtataaatt tgttgaatta tatgctcaaa aataattaaa tattgtggtt ttctcttcat
     3241 atttttcctc ttcgataaat tagatttatt gttttttgta aggtatattt acttttattt
     3301 aatagggcaa aatagttgct tattttttcc tcataatcta taattaatat aaaccattta
     3361 tatatatggt ctaagtttta taatactgta atgcagtaaa atagcatatt gtagctatac
     3421 tacagcaaat taacatacca ttgtagtata ttaattggaa taattttaag tacttcaaaa
     3481 ttccagcaaa acatatatgt gtttttgata ttatgtatat tcgttaatag aatagctata
     3541 cttgttttac ataataaatt atatgatact tgctatatgt aattactata tttaatacac
     3601 ataactatta tacttactat atgtaattac tatatttgat acacataatt attatactta
     3661 ctatatataa ttactatact tggacacata actattatac ttgctatatg taattactat
     3721 actttataca catagttatc atacatgcta tatataatta ctacacttgg acacataact
     3781 actatattta ctatatgtaa ttatactata cttggacata tagttatcat acatactata
     3841 tgtaattact atacttggac acataattat tatatttgct atatgtaatt atactatact
     3901 tggacatata gttatcatac atactatata taattactat acttggacac atagttatca
     3961 tacatgctat atgtaattac tatacttata cacataacta ttatactttc catacataat
     4021 tactatattt ggacacatag ttatcataca tactgtatat taagatataa tactttttaa
     4081 attttatata acacagacac atgcaataaa aaagaaggta tccataataa gctctttgca
     4141 tgtacctaaa taaaaactgt aaaatagaat atataaaatc taatctattt taagtaaata
     4201 caatttcact ttaaaagagg atgtactatg aaataccata tatttttaat cataactact
     4261 atattaataa tcgaactatg taacatttac atatgcaaaa tagcatcttt tggaaacaaa
     4321 aatataacta tacataagaa ttacaaatat atttttttaa taaaaccatt aaccttcttg
     4381 ataataatat tcacaaaatt accattacca ctatattata tattgtttta catagtaagt
     4441 cataaattgc tcttaagcag aaaaagttct actaacaacc attttattcc caatatggca
     4501 gtaataagtt tttgtatttt acaccttatt actgtaagta caatatcact tgttaaaaat
     4561 acaagtccag atataatatt tgcaaatatg acctataggt taattagtat tttaatagct
     4621 tctattttag attttatctt atggtactct atgaataaaa taaaagagca tatttatata
     4681 ataactcaaa atcaaataga gttcagtcta tttttaaaat ttatctggtt cactttagga
     4741 tatatattat ttgatagtat acaaattaca tttgctccac caagttctct aacttcctac
     4801 tttatattgg gaagtaacat attattaatc ttacaactaa ttatattcat caatcatata
     4861 tattccattg aaaaaaatat ttatttagaa aaagaacatc atagactaaa aatgataaaa
     4921 caagaacaat tactaaaagt aaatttatta aagaaaaaag ctaacattga tgaattaaca
     4981 tcagcatata atcgaaaatt tgcttttgaa aaaatacagc attacattaa taacaattta
     5041 ttattttcat tgatatatat cgatttggat aaattaaaga cgataaatga tacatatgga
     5101 catttagctg gggataacta tattattaac ttctcaagta tagttattga aaacttagga
     5161 atagatgaca tatttgctag aataggagga gatgagttta tagttattat gcctaaatct
     5221 aatgaaaaca ccacaaaaga atttatagag aaaataagta aaattatgga taatacgata
     5281 tcttttagct atggtattgt agaagtttct agcgaaaaca aaatgactgt agaagaaatt
     5341 attaatattg ctgatattag aatgtacact aataaacaaa ataatcataa aaggaacaat
     5401 aactaaaatg aatatttaca tgagcttact tgtagtctca ctatgttttt tatcttatta
     5461 tctctatcat tataattttt ttaaatatct ggacataatg attaataact ctaaaaataa
     5521 atacacagta tatattatat attctatatt taattattta atttttatta tttgtactta
     5581 tttaaagttt catctaatta taaattggac aatttttatg ttgattttat tcatacaaat
     5641 taaagtaact tataaaatct ccacaataaa aaacattttt tattcactaa actgctccat
     5701 cattggttta gcaataaata tattttttag gtctttaatg tcaatagtgt taaatatgcc
     5761 agcatattta tttgatagta attctattgc aaatatttac agagtatttc ctatatcatt
     5821 tagctttata gttacaggac tatatttcag ttataaaaat aataaaaata ataagattaa
     5881 ctttgaggca gttttagagg acaaaaaaaa cttaattttc ttattgagcc ttatgtttgg
     5941 aatgtacttg tatctatgtt tgagtttgtc aatatactat actgttggaa atgtattgat
     6001 tttaaaatta tatggaatca agtctgccat aatagttttg gtaggtaact atattgcaga
     6061 aagatatagc tttagaatta ctcaaataaa aggttatgat attaaaaatc aaatagaata
     6121 tgtagaaagt ataaagacag agtatgaaat taataaattg aatgatattg tatatacaga
     6181 tttactgaca ggcttctaca atagaccttt tgtaaatcaa aaactatcag agtggacatc
     6241 aaatcactac aaatttacct tatgttttac tgatttaaat agcttaaaac ctgtaaatga
     6301 taaatttgga caccaatttg gtgataaata catatccact actgctcaaa taataaaaaa
     6361 acttataaat gtagaaaatt ccttactatt tagatatggt ggagatgaat ttttattcct
     6421 tttacagaat acaagttgtg tagaagcaga aaaaataatg attaatataa attatgaatt
     6481 atcaaaatta agtaatactg acgagtatcc ttatgctctt tccataagct atggattagt
     6541 tgagtgggat ggaatatccg atattgaaac tttaatatca aaggcagatt ctttgatgta
     6601 tgaaaataag cttaaaaata aatctacttt aaactagcta gttcagatat tctacaaaat
     6661 atatgttata agagagtact aagaatgtca aaatatatag attttgcaaa tattgaatac
     6721 agtttactaa tgaatgcact ggatgtaagt gttagtaaac acctattaga tgaacacttt
     6781 actgttgttt gggctaatga ccattattat gaaatgttcg gctataccta gctaaaaagt
     6841 taaaaatgac cactgtagcc gagggaatag agaccagttt tcaaaaagat ttcttacaag
     6901 aaatagactg tgatatgtta caaggatacg tgttctctag acctttacca ataaaagact
     6961 ttgaaaaact tatgtttcaa aactcctcca attaacaata taaaattgct tattataagt
     7021 gatattattg tatcaacaaa taaaggaatt gtctcaaaat tgattttttc taatcaaatt
     7081 tttattttga gacattctca tttttttgca taagaaaata cccaccaagc tacggttttt
     7141 cttaccgctg ttcggtgggt attagtagta ttatgaaatc tgaaaacttt aagtattact
     7201 acttccgcta gcgcaatcac aaaggtcgaa agcttcaaag cgaaaatagg ctttttactc
     7261 atcaaacgtc accgtacctg ccaacccatc caccgttatc atttgtccgc tcttaatagt
     7321 tcgtgtggca atgtgtgtag ccataacggc tgggatgcca tattcacgtg cgacaatgct
     7381 tgaatggcta agaggaccac caatgtccgt tacaatcgca cttgcagatg aaaataatgg
     7441 tgtccatgct ggagttgtgg taactgcaac caaaacactt ccaggttgaa agctttcaaa
     7501 atctgctgga ctattcagta cacaagctgg agccgtcaca acaccagtac tggtaccaat
     7561 gcccgtcaac acaattttcc catctttctg cttctgtggt gcttgtgata tagttttttt
     7621 gtttttttct ggcaacttgg atggtgacac ataacccatg tattttttaa gttcagcttt
     7681 tcgaacaggt attatcccgt tcatatcaga tagagacttg tttttatcca actgctctat
     7741 aagtacctcc aattccgatt ttgtgagcca ataaatatca tctaaatgtg aaatagctcc
     7801 tcctcgtatg aatcgttctg agatttcctg aaacatacaa cgaatcagag gatgtcccat
     7861 tcccatcaaa taaatagcat tttcacgcat aggagaggtt tcctgtgccc aatggagcaa
     7921 cttaaaaaat agttttttac gcaatccacc tatgtgttgt aaaatctctt cttctgcatg
     7981 ttttctacgc ttttcaaacg tggtctggcg taaaaaagga ctttcccctt ttccttccac
     8041 aaatgttttt acggattcaa aagttggtgt aagtgtttcc tgcggtgtgg aatgcgcaaa
     8101 atcaaactca taagcggtac gaccaaactc tttaaagtac ttattgattc gatttttcca
     8161 ttctatccat acttcctgtg aaactccaac aggcacaact gaagacatga aatcttctgc
     8221 tatctttatt gcaggactgt tttgcagata aaggttgatg ctgttatttt gctttaccca
     8281 ttctgaaata ccccacaact ccttttccga ttgcagaaca atcgtatcaa acccaagcag
     8341 gaaaacggaa gtatccgtta taccagcacg tcgaactgct ccttgaaata attttgtaaa
     8401 taatgtttca ctgatagaag cagcaggcaa tgtaagctga atccttgtga aataaataca
     8461 tgcggcataa aatattgtct gaataccctc cataatttga tgggcgttca tagtatgcag
     8521 gggcttttct tcccattgtt taatagcatc ctcatatcct tttcgtgccg tttcccagcg
     8581 tgcaacgctg ttcataagtg tcctacgtaa agagcgtggg gaaagggatt tgatagcaat
     8641 caaaagtgga tttgatttag cagaaagata aacatatcca ttaataaccg tatatgcccc
     8701 gttttttggt aataattttt tcgcactttt accaaacata tctatccata aaagctctga
     8761 tgcacggttt acgatttcaa gaccaagcgt ggcgaacaaa ggtgtaacag gatttggcaa
     8821 atgttctgcc aaacttccct ttgtgtatac aacatcctgt tctggcaata cccattctgg
     8881 tggcagaaca gtaattggac gagcctgaac aatgtacaat ttatcttttt ccagtgccca
     8941 ctctacatcc ataggcattt gataatactt ctcaattttc tttccaagct gtatcagttg
     9001 cattacctga ttacgagtaa gagcatattt ttttctcaac ctttcaggaa ccatggtttc
     9061 ttctgttcct tctgaagtac gaaccgtcat aatctcttta tttgccactt catacgatat
     9121 aattcgttcg gaatccttat ccactacgat tgtatcgggt gtaactaagc tagaaaccac
     9181 cgcttcacca agcccccatg cagcgttaat aatcatttcg ctacgtctac cattgattgg
     9241 gtttaacgta aacataatac cagatgaatc ggaaaatgca agcttttgta ctacaacagc
     9301 aagtgcgaca atctcgtgct ttatattatt cttcacacga taagcaatag cacgagctgt
     9361 ccataaggaa gcccagcatc tctttacagc gtcaataact ttatcttcac cttgtatgtt
     9421 aagataagtt tcctgctgac ctgcaaaaga agcgtcaggt aaatcttcag cagtcgcaga
     9481 cgaacggaca gccaccgata tgttccctaa tccggcataa gctgttttaa ttgcgtccga
     9541 cacttcctgt ggcatttctc cattatggaa aagctcccct attttcttag atacatcttc
     9601 aagttggctg gtattattgg aatcaatacc atctagcagt ttattaattc gagactgaat
     9661 atggttcgtc tcaacaaaaa tctggtatga agcagtcgta acatgaaaac cgtctggcac
     9721 agggatgcct gctgtcaata gttttgataa agacatccct tttccaccaa caatttcaat
     9781 ggttgcttgt ttatgttcca gtggcaagac ataataaatc ataatcattc acctccatca
     9841 ttcataattc cgtgcagaaa tatattcatt gtttcatcca acattttttc cgaactatcc
     9901 aatggtcttg acgtgtaact gattgataac atggagttaa ttaacaaacg tgtcacaaga
     9961 gcggtatccg ttttgcgaaa gatgcctgtg gtcacaccat tatcaattac cgattttata
    10021 atatcttgat atgcataacg agcatcttta agtctctttc gatactcttc ttctaaataa
    10081 tcagattctg tatttaacca catcagtaca gttctatact gctctggaaa tctaagatga
    10141 ttaagcatga tttttctaag gcactgttgt ggtgaaggtt caccatcaat aatcctatga
    10201 acttgttgga tagttttttc tatttctttc tcaactgcat atacaacaat ctcatctttc
    10261 gttttgaaaa aatcgtatag acttgacttt cccatgttgg ctaaaactgc aatttctctc
    10321 attgatgttt tttggaatcc attttcagcc atgagactca aagcaacagc aactattttt
    10381 tctcggcgtt ctgcttgttg ttcgggtgta agcacaattc cttttggcat agggcgatac
    10441 ctccttttag cgaccactgg tcgtttcttt tttatttatc atacagcgac caacggtcac
    10501 ttgtcaaggt taattttttt cattgtatat ggtactcgag ataaaaatgt tcattttaga
    10561 aattgctcta tttaagtaga aataggcttc atcattagaa aacaagacta taaatttgag
    10621 atatttatca tgttcaaatt tcatcaatat caaagtttaa aatattaata aaaaaagaat
    10681 tactaagaaa taacatataa agattcaaaa aaggagttga acttaaaatt taattacaaa
    10741 aaatcaaatt taagacaact cctttattct ttatctctac tattctttat ctctatttat
    10801 ttattacaac tccctaacat ttaccactac tgccttaggt ctagtcatag cctcaattga
    10861 atacttaaca ccttgagttc ccataccaga tgcctttaca cctaaaaatg ggaagtggtc
    10921 tggacctctt tcagtcttat tatttatttg aacagtacca acttcaagtt tatcagctat
    10981 ataaaatgcc ttatcaatat cacttgtaaa tactgatgat tgaagcccat actctgattg
    11041 attagcaatt tcaattgctt gatttatatc tttaactctt ataattggaa gtactggacc
    11101 aaatggttct tcccaagcaa ttttcatatc aacatttaca ttatctaaca atgttggata
    11161 gaataaatta ttttttctaa cattgcctgt tattaacttt gctcctttat gtaatgcatc
    11221 atcaaccaac ccttgaacaa aatcagttgc tttattatct ataagaggag tgataactac
    11281 ttcatccatt ggatttccaa ttgtcaactt ctctaccaat ggctttattt ttccgactaa
    11341 tttatccgcc acactctctt gtactaaaat tctctttact gccgtacatc tttgtcctga
    11401 atatgaatac gctccagata ctatattctt agctgcaaaa tctaagtctg catcttctaa
    11461 tactatagcc gcatcttttc caccaagctc caataataat ggtaccattc cagatatttt
    11521 agatatatgc tgaccaactt cagtactacc agtaaagtta ataaaattaa ttcctttatg
    11581 cgttacaaca taatctccta tctcactacc cctacctgta atagtattaa gtactccatc
    11641 tggtatccca gcttttctca taatttctac cacatgaagt gcgctaatag ccccttgtgt
    11701 agcaggtttt aatacgactg catttccacc aataagtgct ggagcaatct ttgacattga
    11761 taaatttaca ggataattaa aaggagatat agctaaaaca gtacctaatg gaacccttga
    11821 aacataagac atcttatttc ttgttccacc agggaaatta tctccactaa tggcttcacc
    11881 ctccatattt tttcccacat cagctgtgta tcttaaaaaa tctgctgttc tctcaacttc
    11941 tgcccttgca gattttatgt ctttggctat ttcaagtacc agtatattag ctatctcatc
    12001 tatattttct aacaataaat cagcagcctt atgaaatata ttggctctct tgtatacagg
    12061 catttcagcc catactttta tactctcttt tgtgtttttt ataacctcat ctacctcatg
    12121 ttttgtcata gattgtactt tcccaacaag agaattatct attggtgagt aaatttctat
    12181 tggctttctc gaattagatt ctacccattt tccatttatt aaatttttat atacattttc
    12241 ttttgtttta agttcattaa acatattttt attcctctct ctgatataac tttgtgtatt
    12301 taaattatag ccatttattc gttatgtaaa catttctttt ttccataaac gtttacctat
    12361 aaaaaaaatt ttaagttaac gtttttctac attcttctat tttaataaca tactcgctcc
    12421 aaatctatat aggtcacact ttaatatcaa tat
//
LOCUS       DAEOTL010000105        12124 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEOTL010000105 DAEOTL010000000
VERSION     DAEOTL010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12124
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.106"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..147
                     /locus_tag="KRH82_003394"
     CDS             <1..147
                     /locus_tag="KRH82_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBG8656652.1"
                     /translation="AGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKS
                     VYKK"
     gene            163..1746
                     /locus_tag="KRH82_003395"
     CDS             163..1746
                     /locus_tag="KRH82_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBG8656653.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            1774..3102
                     /gene="ssnA"
                     /locus_tag="KRH82_003396"
     CDS             1774..3102
                     /gene="ssnA"
                     /locus_tag="KRH82_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBG8656654.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEIAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIISGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            3301..4653
                     /locus_tag="KRH82_003397"
     CDS             3301..4653
                     /locus_tag="KRH82_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBG8656655.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            4845..5954
                     /locus_tag="KRH82_003398"
     CDS             4845..5954
                     /locus_tag="KRH82_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656656.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            6237..7628
                     /gene="hydA"
                     /locus_tag="KRH82_003399"
     CDS             6237..7628
                     /gene="hydA"
                     /locus_tag="KRH82_003399"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBG8656657.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQDKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNPAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            7622..10183
                     /gene="xdh"
                     /locus_tag="KRH82_003400"
     CDS             7622..10183
                     /gene="xdh"
                     /locus_tag="KRH82_003400"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBG8656658.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLVGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEEDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            10335..11681
                     /gene="rpoN"
                     /locus_tag="KRH82_003401"
     CDS             10335..11681
                     /gene="rpoN"
                     /locus_tag="KRH82_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBG8656659.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         4840 a         1401 c         2458 g         3425 t
ORIGIN      
        1 gcaggtgagg ctggaataag aactatagga tttggtcctt ctaaggaaaa tcttgctcat
       61 acaatagatg agtatataga attagaccaa ttattcaaag gtgcagaagg atattatggt
      121 atattaaaat cagtttataa aaaataatta ggagatggtt ttatgagaac tttaataaaa
      181 catgggctta tagtagatgg aaataaaaca ccagcatatg aaggagatat tttaatagaa
      241 aacgagaaaa tattaaaaat atcacaagat ttaaacgaag aagctgacaa agttatagat
      301 gcaaaaggta gagttatatg tccaggtttc atagatactc atagccattc agacctagtt
      361 attttagtta atccatataa tgaggtaaag attagacagg gaattacaac agaagtgttg
      421 ggccaagatg gtatatctat ggcccctcta cctcaagagc atatatcttc ttggagaaaa
      481 aatttagcag gtctagatgg tgaaagtgat gaaattgatt ggaaatatga aacaacagag
      541 aattatttaa aaatgatgga ttacaatggg gtaggtttaa atgaaactta tttagtacct
      601 catggaaacg ttagaatgga agctatggga cttgaagata gacctgctac taaagaagaa
      661 attcaaaaaa tgtgtgaaat cacagagaga gaattaaaag caggagctat aggattgtct
      721 actggactta tatatatacc ttgtgcatac tcattgactg aagaaattat agagatgtgt
      781 aaggtagtag caaaatatga cggagtattt gtagttcacc aaagaagtga agcagataca
      841 attttaactt caatggaaga aatcatagaa attggaaaac aatcaggagt aaaagttcat
      901 ttttcacatt ttaaggtttg tggtaaagca aactggaagt atataccaca agttatagag
      961 cttttagaaa aagcagaaaa ggaaggaata agagtatctt ttgaccaata tccatatgca
     1021 gcaggaagta caatgcttgg agtagtttta cctccttggg cacattctgg aggaactgat
     1081 aagttaatag aaagattaag tgatgaaaac gaaagagcaa aaatgaaaaa agatatagca
     1141 aatggaatag aaggctggga taattttata gaatttgctg gaatagacca aatatttgta
     1201 acaagcgtaa aaacagaaaa gaataaagat acaattggta agagcttatt agaaattgga
     1261 aaaatgagag gaaaagaccc attagatgca acgtttgatt tattaaaaga agaagaaaat
     1321 gcagttggga tggtagattt ctatggatta gaagaacata taataggatt catgaaaaga
     1381 gacgagcaaa atgtgtgtac agatggtctt ttagcaggta aaccacatcc aagagcttat
     1441 ggttctttcc ctaaaatact aggaagatat gttagagagt tgaatgtgtt aacaatcgaa
     1501 gaagctgttt ataaaatgac taaaaaggca gctacaagct ttagtataaa agatagaggc
     1561 gaattaaaag aaggatattt tgcagatata gttatatttg acaaggatac agttagtggt
     1621 tgtgatgatt ttatcaactc tatgcagtac cctacaggta tagattacgt aattataaat
     1681 ggaaattgtg ttgttgaaga aggaaaatac aataaaatta aagcaggaaa agtacttaaa
     1741 aattaaatct tagctttaag gaggaataaa tttatgattt tagtggggaa tgggaggcta
     1801 ataagccaag attctttaaa tccctatatg gaagatggat gtgtagtaat aaatgataat
     1861 ctaattgaag atataggtac tacagaagaa atgaaagcta aatatccagt acatgaattt
     1921 atagatgcag gcaagaaaat aatcatgccg ggtctaataa attcacatat gcatatatac
     1981 agctcatttg ctagaggaat ggcagttcca ggaaaacctt ctgagaactt tttagagata
     2041 ctaaacaatt tatggtggag acttgacaaa cagcttacac tggaagatac aaaatacagt
     2101 gcatatgcaa cgtatataga atgtataaaa aatggtgtaa caacagttta tgaccatcat
     2161 gcaagtccaa atgcaattga aggcagtttg tttacaatat cagatgttgc aaaggatttg
     2221 ggaattagaa cgtgtctttg ttatgaagtg tctgatagag atggtggaaa tacaatccaa
     2281 caaggtatca atgaaaacgt aaactttata aaatacgctc aaaaagatga tacagacatg
     2341 ataaaaggaa tgtttgggct tcatgctgca tttacactat ctgatgatac attaaataaa
     2401 tgtgcttcag agatagctgg tcttgataca ggttaccatg tacatgttgc tgaaggacta
     2461 gcagacttac aatataatgt agataaatat ggaaaaaggg ttttagaaag attcaatgat
     2521 tttggagtac taaaagaaaa aacaatagca gttcattgta tatatataag tgcagaagaa
     2581 atcagtcttt taaataaaac aaatacattt gtagttcata atccagaatc taatatggga
     2641 aatgcagttg gatgttctcc tgcaatagag ttattaaaaa ggggagttac agtaggatta
     2701 ggaactgatg gatatactag cgatatgttt gaatcattaa aagttgccaa tataattcac
     2761 aaacatcact taaaagaccc aagagttgga tttgaagaat cacaaacaat gttatttgat
     2821 aacaatagaa aaatagctaa agcttattat aaaaatgacc taggagtact taaaaaaggt
     2881 gcttatgcag atgttatagt agttgattat ataccacata ctccattgac agaaaataca
     2941 atagggggac acactatttt tggaatgagt ggaagaagcg tagatacaac tattataagt
     3001 ggaaaggtac ttatgaaaga tagaaagtta ataaacatag atgaagaaag tattctagca
     3061 aaaagtagag aattaagtca aaatctatgg aatagaattt aaataattga ttatgcaaaa
     3121 ttctatgaag caggaaccct gtgactttag tcatgggagg ttcagattaa tatacaagta
     3181 agaaacaaga atttagatgt taaaaacaga gcttaaacaa aaataggaat ttaaatgaag
     3241 tatataaata aaaaatatac ggaatagaat attaaattaa atatagaagg gagacccaaa
     3301 atgtctcgag ataaaagccc taaaatagct ccagtagatg aaaggttacc tgtatccaaa
     3361 tcttgggtat tttcactaca gcacgtttta gcaatgtgtg caggagcagt agcagttcct
     3421 atgatgatag gaagtgctgc acgactagat catgctagta ttgttttttt aataaatgct
     3481 tgcttgttta tggcaggtat aggaacactc atacaaagtg ttggtatagg aaatattgta
     3541 ggtgctaaaa taccagtaat agaaggaact agttttgccg ctgtggcagg tatgacagca
     3601 atagcctcat catatagtga ttcacaagtt gcaatacaga cagtatttgg ctctgtaata
     3661 gtagctggat tgttttgtat attacttgct ccagtatttg aaaaattaat aagatttttc
     3721 cctagtgtag ttactggaac agttgttatg gtaataggta tttcactatt tccagttggg
     3781 ataaaatgga taactgacaa caaattggaa gcggttgaac caaactcatt agcattagct
     3841 ttagcagtat tggcaataac tttactttca tttaaattct taaaaggaat ttggaatagc
     3901 acagctatat tggtaggtat agtacttggt acactacttt ccatggcagt tggaatggca
     3961 gattttagtg cagtaaatgg agttggttgg cttaacttaa atgtaccttt aaaatttgga
     4021 atgcctagat ttgaaccatc tgcaatacta tcattgtgtt tgattatgtt ggtacttatg
     4081 acggaatcag ttggtaatat gatagctatt catgaaatgg tagacaaaga agtaacaggt
     4141 aaaaatatta aaagaggtct atttggagat ggaatatcta cagcattatc tggaatattc
     4201 aattcatttc caataactcc atttggtcaa aatacaggaa tagtaggtct tacaggtata
     4261 aaatcaagat ttatagcagt ttacgcaggg gttatattgc tagtacttgg attcttacca
     4321 aaatttgcag caataatagg agcaatacct aagcctgttc ttggaggcgt aggatttgca
     4381 atgtttggaa tggtaatggt tggaggagta aaaactttaa gcaaagtgaa atttgatgga
     4441 actaaaaatg gggttatagt agcagttagt gttggtttgt ctatgatacc actaacaaat
     4501 cctgatttct atcataattt cccaacttgg gtacaaacaa tattccatag tggaataaca
     4561 acaggtagtt tatcagcagt gcttttaaac atattcttca atgaactagg ttctaaaaaa
     4621 gaaaaaaata ataaagttga agaagcaaaa taaaaataaa acaagtaaaa atctatattg
     4681 acttaaagtc attaagtatt aataaaaata attcagagat attaataatt caacaaaact
     4741 atcttatatt ttaaataata taaaaaagta aataaataac aaatacaaat aaaagaatac
     4801 aatctaaata ttaaaaatat ttaatttaag ggagagataa taatatggct aatttaaaag
     4861 ttaatttata tggaatggaa tttttaaatc caattatgac agcggcagga cctggagcaa
     4921 aagatggtgc tctctgtcaa gaggcagcaa aaggtggagc aggagctata tgtacaaaaa
     4981 ctatatctgt attaccagct gatgtaccaa gaccatgtat ggcaaaaact aatagtggtt
     5041 ttttaaacac agaattatgg tcagagcttc caaaagagca atggatagag gaagaataca
     5101 aaaaggtaaa agaaacaggg cttccagtaa tagtaagtat gggatattca gcagagcaaa
     5161 tagctgaggt tgctccttta gtaaagcctt atgcagatgc agttgaatta tctactcatt
     5221 atgtaggtac agacgttgca ccaatagtaa atgctttaaa agctgcaaaa gctgttttag
     5281 atgtaccagt atttatgaaa atgagtcctc atactgacat tcaaactatt gcaaaagctg
     5341 ttgaagaagc aggtgcagat ggacttgtaa tgataaactc atttggacca tgtatggcaa
     5401 tagatgtaaa tacaggatac cctataatgg gaagtaaagc tggatacgga tggttatcag
     5461 gtgcaccaat aagacctcta gcaataagat gtatatatga agcttctcaa gttgtaaata
     5521 taccaataat cggtgttggt ggaatcactt gtggaaaaga cgtggctgaa atgatgatgg
     5581 ctggagcaag tgctgttcaa gtatgtacag aagcaatcct taaagggcct tctatctatg
     5641 gaaaaattgc taaagaatta aatgaatttt tagatgagaa tggatatgct gatgttaatg
     5701 aaataaaagg attaactcat aagaaaatgg cagctagagg gtttagaact cattcagtag
     5761 ctccagtagt ggatgataac aagtgtatca aatgtaagca atgtgtaaca agctgtgtat
     5821 acgaagcttt agaagttaca gataagttga acatagatgc agacaagtgt tttggatgtg
     5881 gattatgtgt aactagatgt ccaaaaggag ctttaagcat ctgctacaat caagtagaag
     5941 ctatgaatga gtaataatta tatagaattt tggtaattaa cttagagtaa taggtattag
     6001 gataataaaa tatatcagat aaacaaacac acattatgca ttaataatac agtctaaagt
     6061 taataatttt attatattga tttaactaaa tattagttta gctgaatatt aatttaatta
     6121 ggtattggtt taatcttaat atagatttac tgcgtataag tgaactaact agattacttt
     6181 aagttaattt tttcatataa aataaattga tacattacaa gtaaggtgga gtctatatgg
     6241 gaattgtttt aaaaggtggg aaagtagtaa caagtgaaaa aacttactgt gcagatgtaa
     6301 gaatagaaga tgaaaaaata gtcgatatag gtcttgatat atcaaaagaa aatgatgaaa
     6361 tagttgatgt tagtgattct tatgttatac caggaggtat agatacacac acacactttg
     6421 acttagatac aggcgttact aagacagcag ataactttga gacaggaaca aaagctgcta
     6481 tagtaggagg aactactact atattggatt ttgctacaca agataaagga tgttctttga
     6541 aagacggatt agaagaatgg catgaaaaag ctaaggataa atcctattca gattatggct
     6601 ttcatatggc tataacagat tggaatgact cggtttgtaa tgaaatggag gatatggtga
     6661 aagagggagt atcttcattt aaactgtata tggcgtataa aggaagcctt caagttgatg
     6721 atggtgtaat ctttgaagca ttgagaaaag cagaagagat aggagggatt attggtttcc
     6781 attgtgaaaa tggggacata atatgtgaac ttgtggataa agcaaagtca gaaaataatt
     6841 tatctccaaa atatcatcaa ttaactagac cagctataat ggaggcagaa gctacatcaa
     6901 gacttatgaa gatagctgaa gttgcaaact ctaaagtata tgtagttcac ttaagctgta
     6961 aagaatcctt agaggaggtt ttaaaagcta agcaaagagg tgtggatgta atagttgaaa
     7021 cttgtcctca ataccttcta ttaaatgatg aattatatga tttagatgga tttgaaagtg
     7081 ctaagtatgt aatgtcacca cctttaagaa ataaagaaaa taatgaaata ttatggaatg
     7141 ctattttaga taatcaaata gacactatag gaacagacca ttgttctttt aattataagg
     7201 gacagaagga acttgggata aacgatttca gtaagatacc aaatggttct ccaggtgtag
     7261 aacataggat gagtctttta tacacatatg gagtctgtaa aaataaaata tctatcaaca
     7321 agatggtaga agtaacatca actaatccag caaagttgtt tggaatgtat cctaataaag
     7381 gaactataga aataggcagt gatgcagata tattagtctt aaatccaaac aaaaaatcca
     7441 aaatagaagc aaaaaaacaa ttacaaaatg tagattatac accttatgaa gggtatgaag
     7501 tggattgtca aatagaacat gtttatttaa gaggaaaaga agtagttaga gatggagaat
     7561 taatctgtaa tactccaagt gggagatata taaataggcg tctaacaaag ggggctagag
     7621 aatggtagaa tttatattaa atggagagaa agttgttgca aaagaaggca aaaaactttt
     7681 agacttcctt agagaagata tgaatataac ttcagttaaa aatggatgtt cagaaggtgc
     7741 ttgtggaaca tgtatggtta taatagatgg taaagctact aaagcatgtg tatttaaaac
     7801 tgataaatta gttgggaaaa acataacaac tatagaggga ttatcagaga gagaaagaga
     7861 tgtttttgca tattcttttg ctagtcaagg agctgtacaa tgtggatttt gtattccagg
     7921 tatggtaatt agttcaaaag cacttataga cgttaataat aatcctactg aagatgatat
     7981 aaagaaagct ttaaaaggta atatatgtag atgtacaggg tatgtaaaaa taattaaagc
     8041 tgtcgattta gcagcaaaga tttttagaga aaatatagat gtgccaaaag taaactgtaa
     8101 aggtctagta ggtgaaaatc ttcctagagt tgatgcagtt ggcaaagcac ttggatattc
     8161 tgaatatgta gatgatatga gaattgaggg tatgatttat ggctcagcag ttagagctaa
     8221 gtatcctaga gctttagtta aaaaaataga tatagaagaa gcaaaagctt atccaggagt
     8281 tgttgcagtt ctaacagcta aagatattcc aggaactata aaggtaggac acttaaagaa
     8341 ggattgggat actttaatac cagaaggtga aataactaga tacttaggag atggaatagt
     8401 tttagtagca gcagaaacta gagaagcgtt agaagaggcc aaaaagctag ttaagataga
     8461 ttatgaggaa ttaacaccat taagtactac agcagatgca cttagagaag atgctccaaa
     8521 gatacatgag acagggaata tacttgttaa ggaacattta gtaagaggaa acgctaaaga
     8581 aaagatagaa aattcaaaat atgttgtaac taaaagatat actacacctg ctacagaaca
     8641 cgcattttta gagcctgaat gtgcagtagc tggtccttat gaagaggatg gagtaataat
     8701 ctattcaaca gaccaagggg tgtttgccac tcaacatgaa tgtgcagata tgttagggtt
     8761 accatatgag aaggtaagag ttataaacaa aatggtagga ggagggtttg gtggaaaaga
     8821 agacatgagt gttcaacacc atgcagcctt acttgcatac catacaaaga gatttgtaaa
     8881 agtacagtta acaagaaaag aaagtattat tgttcatcca aaacgacatg ccacagaaat
     8941 ggaatttacg acagcatgtg atgaaaatgg atacttaaca ggtatgaagg caacgataat
     9001 atctgacaca ggtgcatatg cctctcttgg aggaccagtg ctacaaagac tgtgtactca
     9061 tgcagcagga ccatacaatt atcaagatat tgatataaca ggaacagcag tatatactaa
     9121 taaccctcct ggaggagcat ttagaggatt tggagttaca cagagttgtt ttgcaactga
     9181 atgtaatcta aatttacttg ctgaaatggt tggaatatct ccttgggaga taagatataa
     9241 aaatgcaata agacctgggc aagttttacc aaatggtcaa tttgcagatg aaggaacagc
     9301 aatggcagag acactagaag ctgtaaaaga agagtatgaa aagcatccac gtgcaggtat
     9361 agcttgtgct atgaaaaata gtggggttgg agttggtata cctgatgttg gaagatgtag
     9421 attggtgata aaagatggca aagttcacat aagaacaagt gcttcttgta taggtcaagg
     9481 gcttggtact gttatgactc aagtagtttg tgaaactgct aacctacttc ctgaaaatat
     9541 agtgcatgaa gttccagata ctcatttaac accagactct ggtaatacta cggcttcaag
     9601 acagacagta tttacgggag aagctactaa ggttgcatca aataagttaa aagaagcttt
     9661 agactctggc aaaactttac ttgatttaga gggagaagag ttttatggag aatatgaaag
     9721 tattacagat aaaatgggtt gtgacaaaga aaatccagta agtcatgttg cttatggata
     9781 tgcaacacaa gttgtaattc tggatgaaaa tggaaaacta gaaaaagtag tagcagcaca
     9841 tgatgttgga agagctataa atccaatcag tttagaaggt caaatagaag gtggagtagt
     9901 tatgggtctt ggatatgctc taaccgaaga ttacccagta gtcaactctg ttcctacagc
     9961 taagtttggt acattaggtt tatttaaatc tacagatata ccagaaatac aagctttaat
    10021 agttgaaaag aacaaagatt tattggctta tggggcaaaa ggtgtaggag aaatttgtac
    10081 agttcctact gcaccagcag tacaaaatgc ctattatgta tttgataaag aatttagaac
    10141 tgagctacca ctacaaaata ctccatatag taaaaaaaag taacaaaaaa aagaaatatt
    10201 aaataaaaaa atagatgaaa ttgtaaataa aaaaaaccct tttgcataag gtatatttta
    10261 aatgatagaa tatacatata caggagggtt tttcttttat aaaataagtt taataaaatt
    10321 gagaggtgag cagaatgaat tttaataata gtctagaatt aactcagtct cagaagctaa
    10381 taatgactac acaacttaag caatcattat caatattaaa tatgagtaag ttagagttag
    10441 aagaagagat aaaaagagaa gcagagaata acccattagt tgaagtcgag aaaagtgggg
    10501 agataaattg ggaagagtat ataaaagaca tggataggtc aagacgttta gatagaacag
    10561 agataagcta taatcctgat aatgaagtta atctagaaaa tttagttaaa tattcgtcaa
    10621 atttatatga agatttaaaa tttcagataa gcctgtataa acttacagac aaagaattgg
    10681 aagtctgtga gtatataatt gatagtttag atgaggatgg atatttaaga actgaggaaa
    10741 aagtaattgt tgatacctta aagatagatg aagaactttt tgaaaaatgt ttaattagtg
    10801 ttcagcagtt ggaacctagt ggagtagggg caagaagtct ttcagaatgt ctgatgatac
    10861 aaatggctag tttaggaata tataatgaaa ttttagagga aatcgttaca aaagacttaa
    10921 atttaattgc aaataataaa tataaagaga taagtaaaaa gtacaatatg tcattacaaa
    10981 aatgtgttga actaataaac ataattaaga cattagaccc caaaccagga agaacttgtt
    11041 cagtagagaa aagtgtatac attcaacctg atgtaacagt agaaaaaatt gatgatgaat
    11101 ttattgtata tttaaatgag aaagattctt atcaaataag aatcaatagt tattataaag
    11161 acatattaaa aaattcacag tctgatgaaa gtgcaaaaga atttataaaa gaaagactaa
    11221 attcagcaac aggacttatg aaaaatatag agagtaggaa aactacagta cttaagattg
    11281 cagaagagat agtaaaagct caagatgaat ttttgagaaa agggacaaaa tatataaaac
    11341 ctttgaaaat gaaagacata gcagaaaaat tagaatttca tgaatctact ataagtagag
    11401 gtgtaaatgg taaatatatg ctaacacctt ttggcgtata tgaatttagg tactttttca
    11461 gtagcgccat tgagactgag aataatgaaa tggcatctag tacaagcata aaaaaaatta
    11521 taaaggaaac aataaaagac gaaaataaaa agaaaccttt aagtgatgac catatatcta
    11581 agttattaaa agaaaaagga atcaatgttg caagaaggac agttgccaaa tatcgtgaag
    11641 aattaggaat cccatcttca agtaagagaa aagaatacta ataagtaaaa gacaaatatc
    11701 agtatggtaa ggggaaaagg ctaattaaga gatgaatgta gattgggcta aaaattttat
    11761 aaagtaaaat aatagaatat ggaaaagtat taaaatgcta taaggtatta aaaaactggg
    11821 gaacattaaa acattaagat agcaaagagc ataaaaaact aaagaagatt aaaacattaa
    11881 agaacattag agctttgagg aatattagaa ctttaaagaa tattaaaatt tataaaatat
    11941 aaaaatacta aaaagaattg aaaaactggg gaacattaaa atattgtaaa atgctaaaaa
    12001 actagaaaac ataattaaat aagtgcttat aaagaatgat taaattaaat aagtgtttgt
    12061 aaagaataat tagatattag aaaaagaaga atacctagat aaataaacta ttattaaatt
    12121 taat
//
LOCUS       DAEOTL010000106        11851 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEOTL010000106 DAEOTL010000000
VERSION     DAEOTL010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11851
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.107"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            29..577
                     /locus_tag="KRH82_003402"
     CDS             29..577
                     /locus_tag="KRH82_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656660.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            839..1147
                     /locus_tag="KRH82_003403"
     CDS             839..1147
                     /locus_tag="KRH82_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656661.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(1309..3099)
                     /locus_tag="KRH82_003404"
     CDS             complement(1309..3099)
                     /locus_tag="KRH82_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656662.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(3099..4826)
                     /locus_tag="KRH82_003405"
     CDS             complement(3099..4826)
                     /locus_tag="KRH82_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656663.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(5071..5337)
                     /locus_tag="KRH82_003406"
     CDS             complement(5071..5337)
                     /locus_tag="KRH82_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBG8656664.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            5635..6747
                     /locus_tag="KRH82_003407"
     CDS             5635..6747
                     /locus_tag="KRH82_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBG8656665.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLAGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(7120..7629)
                     /locus_tag="KRH82_003408"
     CDS             complement(7120..7629)
                     /locus_tag="KRH82_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBG8656666.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(7631..8278)
                     /locus_tag="KRH82_003409"
     CDS             complement(7631..8278)
                     /locus_tag="KRH82_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656667.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(8292..9464)
                     /locus_tag="KRH82_003410"
     CDS             complement(8292..9464)
                     /locus_tag="KRH82_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8656668.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSAGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            9732..11108
                     /locus_tag="KRH82_003411"
     CDS             9732..11108
                     /locus_tag="KRH82_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656669.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(11359..11718)
                     /locus_tag="KRH82_003412"
                     /pseudo
     CDS             complement(11359..11718)
                     /locus_tag="KRH82_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
BASE COUNT         4175 a         1890 c         1452 g         4334 t
ORIGIN      
        1 atattgtaac taatacttat tctaaggagt gatttttttg aacgaagatg ttgtaactaa
       61 tgaaactatt gacaaagatt atgctattga agaagttcgt atggcatgca aacattttgg
      121 tgatttatat ttttattttt ccaaagtgtt atttgaagag tttggtgaag ataaaactag
      181 cgaaatatta agaaaagttt tatttgaaag gtctgaagaa agagctattg ctatgagaga
      241 gagagctcat gaaaatggag atgaattaat tgcagacaat attattagca caactgatgt
      301 tccatttcta ggatgggttc ctgaatttga agagttacat tgcccctatg gagcttcctg
      361 gcttttaaga tttgaggaaa atccttggtt taaaaaattt gcttctcttt actgtgatgt
      421 tacagatact actgtagctg aagtatttac aggagatact tcccataaaa taacaaaaaa
      481 cattctatgg ggagataaaa gttgtgaaag aatatatttc catgatgaca aggtatctga
      541 aggtaaatat acttatggaa ataaaaactg taaataaata atttaaattt tctatattca
      601 tatactatat tttgtacttt ttcatataaa tattataact agtcttttat tttacttttg
      661 tttaacctaa agataattta cttttaatct atatgaatta tcatataaat aatcagaaag
      721 ttatctttat aaattatagt tttagattta taatttataa aatatttatg ttctttgtaa
      781 aattttttag aagcttctaa tgttatgcta taaaactatc ttgagaaggg ctgattgaat
      841 gtttaataaa atatatgaaa agaaagaatt tatagttttt caagttaaaa aaggttatgt
      901 agtttataat actagaaaga gttttgaaga aggtcataca catttaaagc attttgaagc
      961 agcaaagaca gctattgatt tagcaataaa taaaaagatt cctagaagca aagatggata
     1021 ttatctgact agtttaattc gcataagtga tgatggttat tacattgata agttaagcga
     1081 attgttatat gttagagaac aaaaaggtaa aaaagaaaag tactgtaatt ctggttatca
     1141 gatgtaacaa gactagttgt gaattataag taccaatcat aaataccttt agtcttaaaa
     1201 tcaaagagta tcagtaaatc tataaaaaaa caacttactg atactctttt taattatatg
     1261 attaatattt gaatttgata caaaatttta tacaaaagtt tatgttatct attctgattc
     1321 tttgtctgca aattggctat tataaagctt ctcataaaat ccaccctttt ccattaattc
     1381 atcatgattc ccctgctcta taatacttcc attattcata actaaaatca agtcagcatt
     1441 gcgaattgta gaaagtctat gtgctataac aaaactagtt ctaccattca taagatttct
     1501 cattgctttt tgaagcataa gttccagcct agtatcaaca gaactcgtag cttcatcaag
     1561 tatcaatatt gaagggtctg atataaaagc tctagctatg gttaaaagct gtttttcccc
     1621 tagagatata ttagatgctt cttcatttaa aaacatattg tatccatctg gaagagtggt
     1681 tataaagtga tgaacatttg ctacttttgc tgcttgtata atttcttctt tagtagcccc
     1741 aaatctacca tattctatat tttcaaaaat ggttccatta aataaccatg tatcttgaag
     1801 caccatacca aacattgaac gcaaatcttt acgtttcata tctcttatat ctactccatc
     1861 aattttaata gcacctttct ttacatcata aaacctcatc aataagttta ttaatgttgt
     1921 tttacctgct ccagtaggtc caacaatagc taccatctga ccacttttta cttctgcatt
     1981 taaatcttct attaaagttg aattttctcc atatccaaaa ttaacatgct caaatgtaac
     2041 atttcctttt acattttcta tcttaactgg attttcaaca tcaggtattt cctcttcttc
     2101 gtctaaaatt tcaaatacac gttctatagc tgcaaaagaa gattgtatta ctgtagataa
     2161 ctgagtcatt tgtgaaagtg gctgatttat ctgccatata taacgcacaa atgcttgtaa
     2221 atttcctact gttattcctc cacttactgc atatatagaa ccgacaactg ccacagctgc
     2281 aattccaaag taagttacta atgaaaccat aggattcatc atacttgata taaattgtgc
     2341 cttaaatcca ttttcacaaa gttcttgatt tactttttta aattctttta tagaatcttc
     2401 ttctttacca tatagtttta tttcattaaa tccagtatac atttcttgta ctttcccatt
     2461 taattttcca agagcatttt gttgcaatga aaatctactt tgagattttt ttactacaaa
     2521 tttagataca aaataactaa ttggaattat aaaaagagct ataagagcca tatatatatt
     2581 aattgtaaac atcattgaaa gtgccaaaat tatgactaag attgagttta caatttgcat
     2641 aaaactctgt tgcaatgcat ttgatattgt atctacatca tttgatatac gacttaatac
     2701 atctccaaaa ctattactat caaaataact aataggcaat cttcttattt tattttcgac
     2761 ttcatttctt aaatctctca ttgtgttttg aatagcattc gtaagtagaa aacttgaagt
     2821 atacgtaaaa attgcattgg caaaatatat acatgctaaa atcaccaata tttttgttac
     2881 ataatcaaaa tttacggaag cccctggtac tccttttgcg atactaatta catctttagt
     2941 caattgtgtt attatcaatc cttcagtttt aggtgcaagt gcattcatag tagctgctga
     3001 aattatacat ataatagcta taataaagga aaatttatat ttctttacaa atggaagaag
     3061 tctaccaatt gttttcttaa aacctttaga ctttttcatt attctaattc ctcctttttt
     3121 aactgagatg ttgcaatttc atagtatatt tcacagtttt ttaataattc tttatgagtt
     3181 cccattccta caacttgtcc ttcattgagt actataatct tatcagcatc aataatagaa
     3241 ctaattctct gggcaacaat caatacaatt gcatcttttg tttccttctt caatttagca
     3301 cgaagtattg catcagtttt aaagtcaagt gcagaaaaac tatcatcaaa aatgtatatt
     3361 tcaggtcttc ttataatagc ccttgcaata gaaagtcttt gtttttgacc tcctgataca
     3421 tttgctccac cttcactaat caattcatca aactttctag gtttttttga tataaactca
     3481 tatgcttgtg caacttttgc ggaatattct aattctgact ctcctgcctt atgtttccca
     3541 aatctaatat tatttgctat gctaccagta aaaagcagtg atttttgagg tatgaatcct
     3601 atcttttttc ttaaagcttt taaatcatat tctcttatat ctactccatt tatcttaatg
     3661 ctaccttctg ttacatcata aaatctaggt atcaagttaa ttagagtact tttcccacta
     3721 ccagtacttc ctataaaagc gactgtttca cctgtttttg cagtaaatga aatatcctta
     3781 agtacagaag cttctccatc tggataggta aaagttacat tatcaaattc tatgataccc
     3841 ttattttcag tatccttaat tccattttca ggatttttta tcaatggttc ttcatttaat
     3901 agttctttta ttctatttgc agatacctct gctcttggat acataataaa taccattgaa
     3961 aaaagcataa ttgaaaacat ggcatggaaa agatattcca aaaatgcaac caactgtcca
     4021 acttgaagct ctccaatatt tatcttctca cttgaaatcc aaaatacagc caaaacagct
     4081 atatttaaca gtaaaaagaa tgctggttga gtaattgaca taagcttaaa tagtttctta
     4141 gaaacattag cataatatgt atttgttttt tcaaatcgct ctgtttcata atcatcattt
     4201 ccaaaagctc taattactct tattccagtt aaattttctc tcgatataag gtttaattta
     4261 tctagtcctt tttgttgttt tgaagatatt gcctgagata cttttgctat tattgctact
     4321 ccaataatta taaaaggtac tgatatagcc aatactatag aaagttccac actggttcta
     4381 attgtcatta ttatacttat aatgaacata actggagtta ataaggcagt ccttagtagt
     4441 atattaacaa attgttgaat ttgaaatgca tcattcgttg ttcttgtaat cattgaagaa
     4501 attccaaatt tattgtattc agtatgtgaa aattcttgtg atttctcaaa tatgtcattt
     4561 cttatatctc tggttacact tgttgatacc ttagcagaac aataacccaa caatatacta
     4621 cctacaaccc ctataataga aataataaca atcactattc ccatttgttt tatgtaagct
     4681 atattctgat ttgcaatacc attgtcaatt attttagcta ttatagttgg aatccccaac
     4741 tcgactaatg caaaactaaa tatagccagt atgtttaata ctattaataa cttataattc
     4801 tttaaataac ttaaaattaa tttcatattt ttctcctttc ttaatttttg agatagtgta
     4861 atcatgtaat aatactaaat ttataaatgc ttaattttat aaaaaaagga gaaaagagtt
     4921 aacgcactct cttctccagc atattctttt taatacaccc tccgacaagt cgcttatatg
     4981 ttaacatatt tgacaagtaa tgtcaattca tatagccaaa agtcttttaa atgcttcgtt
     5041 tcataacatt gtaacaaatt ggcatgtaat ttatttttgt tttttactgt attccaattt
     5101 tacaagttct ccaatattac tagctttctt aaaattcaaa ttagtcttgt ctataccaga
     5161 cttaaatagt gaaatccctc tccccaatat tattggcaat atatatatat aataatcatc
     5221 aattaagtta tctttcataa ataattttac tatatcgcct ccaccaacta tccaaatatc
     5281 ttttttatcc ttctcttttc caatttgctc aattaatttt ttaggttcta aattaattta
     5341 tagtgtgatt attctatgta aacatcactt ttttactcat tcaataatac cctattaata
     5401 aatcctcaaa ctaatttaaa taaactttgc ataaaattaa aaatatatta tataaataat
     5461 ttaaaactac actaacttat tgaaaattct aattattaca aataaatatt gctctctgtt
     5521 aacgctagtt ctataatata attataagct attaatatta taaagccgat attactaata
     5581 taataattat aatacttata gttaatttac ttttgttgaa aggtggtaaa taacatgaaa
     5641 atttcagaag tcgctactcc aaattttttg ctagatttag accagttaga aaagaatata
     5701 gataaaattc aacaaatttg tacaaataat aataaacaac tttggcctat gcttaagaca
     5761 cataaaagta cttacatagc gagacttcaa aaaaatgcag gtgctagtgg ttttctagct
     5821 ggaacacttg atgaaggtga agctctgata aaagcaggtt ttgaagatat tatgttggct
     5881 tatccttaca tgggagaagt aaatataaat agaattgtga ctatggcatc aaaaataaat
     5941 ttaatctgtg ctacagataa tatagaatgt gctaaggctt atagtgaagc tttttctaaa
     6001 tcaaaaatag agtgcaagct acttattatt gtagattgtg gcttacaccg ttttggggtt
     6061 gaaccagaaa aagtggttga acttgctact gaaatttcta agctagaaaa catcaagatt
     6121 gttggtataa gttcgcatcc aggtcaagtg tatggttgta gttctccaga aggtgttcca
     6181 gatgtttgtg ttcaagaaga ttcttctatg gagaaagcat acaaagctct aactgataat
     6241 ggatttaata tagaaattgt cgcttctggt agtactccaa cagttgaatc tgaagctgct
     6301 tctaaaacta taactgctgt aagacctgga aactatgtat actatgatgc tatacagata
     6361 ggtttaggtt gtgctactga agatatgtgt gctcttactg ttgtgtgcac tgtaatctca
     6421 aaaaatagca gtggatacta tttaattgat tgtggaagta agtgccttgg acttgataaa
     6481 ggtgcacatg gaaatagtag tattgttggt tatggtaggg tatgtggaca tccagaactt
     6541 actattgatt cactttcaga agaagttgga aaaattaaag taaatggtga aactgatata
     6601 aaaattggtg atagaataag aattatacct aatcattctt gttccactgc aaacttgaca
     6661 agtaatttat taggttttag aggagataca atagaaaaag tcatagaagt agatattcgt
     6721 gaaaattcaa aacaaatcat cctttaaaaa cacatttatt ctgatattaa catgaaagta
     6781 tatttttctt aaaattattt ctaataacta atgttaatgt tggataaata aaaaacataa
     6841 attctagaaa tataaattta aaagaagagg ctgtctcaaa atagagataa gcctctcttt
     6901 cattgttgaa attatgaaaa tatacttgat ttcatacaaa gagagtatct catgaactaa
     6961 aaagttcact ttgagatact ctcttctttt ttaattgata tacaatatac atattaatta
     7021 ctatattatt ttattactat atatcaatta ctattcatca attcttgcat atattaattc
     7081 ttatatatca tttataatta ggctataatt ttatgttatt tacattaatc ccataacagt
     7141 gagtaaaact cttactatta acatccccac tattgcatca aatataggaa ctgccaacag
     7201 taacattcta tacttagtac tggcatttgc tacaagcact attctggcat aatgaccaac
     7261 tagagtaccc attaacatac atggcataat taatatggtt gcttgtggtg cagtgattag
     7321 accttgtgca aataagtttg cagctgtagc tgctcctgct gccttagcaa agaatgctgc
     7381 tatcaaaact acaacagatt ccccaggtag tccaaaaata cccattactg gtccaaaaat
     7441 atttcctaaa atatcaacta aaccagttaa ttgtaaaaac tgcactatta cataacccat
     7501 tatcatggct ggtaatatct gttcaacacc tatgtaaaaa cctttttttg ctccccccat
     7561 aaatatctca acagcagttt tcttaggttt actatttaca attgcatttc cagtattttg
     7621 ttgactcata ctacacagcc tccttagcct tattcttttt atttcttaca cctatgatta
     7681 atctaactag attagcacca agtattttac agaatatctc tataaggatt attggaccta
     7741 atgccaataa tgctattggt aaaagtggag cttgagtatt tattgtgttc agtataacag
     7801 ctgaaccagc atattgatat gctacaaata tagttctttc atcatctgtt atttccccac
     7861 tttcaaataa ttctttcgtc attattgagg ctacatctga actagtaaat gaagatacaa
     7921 atgctattcc tgctattcca ggtataccaa gcagaggtct aagcaatgga ttaaatatct
     7981 ttgatgccgc tttcattcct cccatagatt caactacatc tataagacct acagcaaaac
     8041 agacagttgg aatcaaagtc agagcaaata agaaaccatc ttttgctccc gttcctcctt
     8101 tacccataaa gtctacacca tctgcaatag taccaaatga acctgtcaga ttagcaaaat
     8161 ctaatgcttt aaggaagcct tgactatctt taaacactcc tgaaaataat actatcaata
     8221 caaataaaga taaataccct ttccatgtta ccttattatc tccagctgtt acatccatat
     8281 aaaatccccc tttatacctc aaatttatct aagtttaaaa taactgtaga aattaatttc
     8341 accctctcaa acatagaatc tactactgca tattctcttg atgtgtggtt ccattcccct
     8401 cttacaccaa atgaacagat tgtaggaacg tttgcaatag ttaaataact tgcatctgaa
     8461 ctacctccaa gtctcttagc atttaattct ccaaatccat tttcttttga cacttcattt
     8521 acaaatgtat gaaatctcat aacatcttct gtagtttcaa atggcatcat ttcacttata
     8581 aaattaactt ctgtagaagt tccttctatg taagtttctt tacatatctc tctaacttgt
     8641 tctttaacat tctccatttc ttctactttt tcaaatctaa ggtctacttt tatactacaa
     8701 tcttctggaa tagaattttc cactcttcca cccttaatca cacttacact tactgtagtt
     8761 ccaacatcta aattagtcaa tttttgtatg cgtagtatct tattagccat ttcttctata
     8821 gcatttcttc caccttcaaa atcattacct gcgtgtgttt ctacaccttt tacatgtata
     8881 ttacatccga ttcttccttt tctacctaca cacaaactat tatctactaa tccagtttcc
     8941 atattaaaag cacaaagacc accttttgct tccctcaata taacatctgc acctgctgaa
     9001 tccttatgtc ctatctcttc atctccagaa aatactattt ttattggtct ttctttgtat
     9061 cctattttat ttaaagcttt aataacatat aaggaaatta ttataccacc cttcatatct
     9121 aaaacacctg ggccatatgc ttttccttct attattttaa atggattctc tccaaatgta
     9181 cctgtttcaa agacagtatc catgtggcct gaaaaaatta taggcttttt atttatatta
     9241 gaaccaagtg tacctatcaa tgtactacca ttatctccaa catctactaa ttcgcaatct
     9301 aaaccttctt tttcaaactc aaactttaat ctcttagcca atttatttac gctttcttta
     9361 caatgtgtat agctttccat attaacaatc tctttccata atgaaactat ttcttctcta
     9421 ttctcatcaa caaacttaga aatttcattt aaatatgtat tcataatctt ctcctttatt
     9481 ttcaaataaa atgtatttct ttcctaaaac ctaagtttat tttaggaaat cttaaaagac
     9541 tagtccttaa ttacaaaata gcacaattat tcttgacagt caacatattt ttcagtcttt
     9601 tttatatttt ctgatttttc tttcaattat ccttttgtaa aataaattga cgcgttttat
     9661 ctactattat aaaatgaggt tataaattga ttgattagtt acaatactct cgaaatttta
     9721 aaggaggttt tatgaaatat aaaattggtt ttttgacaac atcttatttt atgtcagata
     9781 agtttaaaca agctcttaaa gaattaaatg atacttgtga aattacattt attgagctca
     9841 aaggggagaa tccttttaat aatttaccta atatatacta tgagcaagta gataattttg
     9901 atggatttgt atgcagtggt atagttccat atagtgaact tataataaat ataaaagaca
     9961 taaaagttcc attaaatttt ttaaagcttg atgaaagaga tttttataaa tacttattca
    10021 aattattaaa tagccaaaaa gatattgact ttacaaaatc atttatggat tttttaagag
    10081 aggacaacaa ttattatgat atatattcat taatagactc taataaatgt ccatatacaa
    10141 ttaaagattt taatatccct caacctgtat atgactttaa aaaattaaat gataaattat
    10201 tggaaataca tttagactta ttgcgagata ataagattaa cctttctttt actagaaatt
    10261 acatcattag ttgtgaactt aataagcttg gatatgattg tatttacatg gttccatcta
    10321 cagaatcaat cctgaataca tttaaatctc tggtgaatga aataacatta caaaacttag
    10381 acaaaaataa atctgcaact tgtatagtta cagtaaatag ttcagagtac ataaatgaag
    10441 atttgatatt taaaaatgat gagatacaaa atcaaatata taacactata ttaaattctc
    10501 tatcaagaca tggattctat ggagttcagg tcaaaaaaaa tgatatgaaa atagagatac
    10561 acactactaa agaaatgtta aacaatatga ccaataacta tacagatttt tttatttcag
    10621 aagatttaaa agaaattaaa tatagcttaa atataggttg gggcattgga aatacaaata
    10681 ttcatgcaga gcaaaatgct cgtcaagcta atggtaaatc tgcttctttg aatggaaact
    10741 gtacttttat agtaaatgat actaatgata caataggtcc tttatattca aataaaaatt
    10801 ctaataatat tgaagatagc tcaatagcca ataaagttgc ttcttttata cctctatcta
    10861 atacaaatgt atctaaaatc atgtgtatga ttaatgatag aaattcaaat aatgtgtcag
    10921 cagaaatatt agcagactat atgaacataa ctcttagaag tgctaataga atattgagta
    10981 ttttatataa agcaggaatt gcaactattg taaatacaaa actcgataat caaagaggaa
    11041 ggccaaaaaa aatatataaa gttgatttct tatcttttct aaataagatg cagaaattaa
    11101 attcttaata tttaattttt taataaaagc aatgtatttt ctctaatttt aaagaatcaa
    11161 aatgtttaaa ttttattaga atatacaact ttttacttta aaatacctaa accttttatc
    11221 agtgaaataa accataatat atcgtaactt attagaaaaa caaaataatt tcatatacaa
    11281 ataataaaat agccactaca atccataatt tgcagtggct actttttaca ctatcactta
    11341 ttacttaatt tttaaaaatt aattgtattt tttaaataat ttatacatac ctattatcag
    11401 taaagcaata aatacaagta tatctataaa aataattatt gtaacatgtc tggcaatatt
    11461 gtaaataaaa agtatagaga agatttctat agacaacgct acaaaacaca taaaattcgt
    11521 taaataatct gcaatagtat cactataaaa agcatgtatt tgtaaccatc tccatataaa
    11581 tggacgtaaa agtattctga atacaacaca aatgacaggg taggcataaa taaatttttt
    11641 atctacataa ttagctacac cattattcca ttggatagga atttgaggtg gcaactttgg
    11701 aaatactgtt attgcaattt aaacactacc tctctattct attaatttat aactataata
    11761 tagtcttaaa tattttcact ctataaaatt gtatatttag tatatcttaa aatcaaacta
    11821 attatctttt ataagttttc atacaataat a
//
LOCUS       DAEOTL010000107        11714 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEOTL010000107 DAEOTL010000000
VERSION     DAEOTL010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11714
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.108"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            428..1702
                     /locus_tag="KRH82_003413"
     CDS             428..1702
                     /locus_tag="KRH82_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBG8656670.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVID
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENIFKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRH82_003414"
     CDS             complement(1909..2226)
                     /gene="trxA"
                     /locus_tag="KRH82_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBG8656671.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2493..3245
                     /locus_tag="KRH82_003415"
     CDS             2493..3245
                     /locus_tag="KRH82_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBG8656672.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGEKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3232..4113
                     /locus_tag="KRH82_003416"
     CDS             3232..4113
                     /locus_tag="KRH82_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBG8656673.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4339..5694)
                     /locus_tag="KRH82_003417"
     CDS             complement(4339..5694)
                     /locus_tag="KRH82_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBG8656674.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
     gene            complement(7601..8110)
                     /locus_tag="KRH82_003418"
     CDS             complement(7601..8110)
                     /locus_tag="KRH82_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBG8656675.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(8321..9730)
                     /locus_tag="KRH82_003419"
     CDS             complement(8321..9730)
                     /locus_tag="KRH82_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656676.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(9734..10864)
                     /locus_tag="KRH82_003420"
     CDS             complement(9734..10864)
                     /locus_tag="KRH82_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8656677.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(10876..11679)
                     /locus_tag="KRH82_003421"
     CDS             complement(10876..11679)
                     /locus_tag="KRH82_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656678.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
BASE COUNT         4213 a         1814 c         1258 g         4429 t
ORIGIN      
        1 tatacttgta catcttttat aacatataaa atcttttttt ctaattatat acaatatatt
       61 ttccattatg ttctaatcaa tttctttact atttttacaa ctttattagt catattcata
      121 attatttcta attagtgttt aacattttat gtaaaattta taaaaaaatg tatataaatt
      181 aaaataagtg actatactaa aaatatgata cggataaaca ataagttcaa cctatctccc
      241 ccaaaatcaa gtgagctaca gtttccccca actgtagctc attttcgtgt aatttaataa
      301 acatctcaac aagaattaat taacgaaacc ccttataaaa acataacata tattaaacaa
      361 gctcttgatt aaaacttgag cttttttaat aaaaaacaga atagtttatt agataagggg
      421 tttttttatg caattcatgg atgtatctaa atacattgaa ggtgcaaatc ttaaagttaa
      481 aactaaaaat ggtgaaactg ttaaaagaat atattttaac aactctgcca ctccattagt
      541 tttaaaaaac gtaatagata acttaaactg tgagattcct tggcttactt atattaatgc
      601 tccaggaata atctcagaaa aaaatacttt aaaatatgaa aatgtacgct ctactatcct
      661 caaacttatt gatggagacg aagaaaagga ttctgttatt tatgtcaaaa atgctacaga
      721 aggaataaac ttcttagcaa aattttttaa agatgaaaat ccagataaat ttgttattac
      781 cacagcaatg gagcatatgg ctaattacct gccttttaaa gttaattttc ctacaaaagt
      841 tgttggaatt acagaaaaag gagaacttga tttatgtcaa ttagagaata tatttaaaaa
      901 ttatgctggt aatgtatctc tcgttacagt tacaggagct agtaatgtca caggtataac
      961 cactcctata tatgaaatag caagaatagc tcataagtat ggtgcaaaga tattggtgga
     1021 tattgtgcaa gtaattcagc ataaaccttt ttcaatgatg ccacatgaat gtgatgagca
     1081 tatagatttt gttgttttta gtgctcataa atgttattct ccactaaatg gaggagctct
     1141 ggtaggacct aaaaaattct ttgaaaaatt taatcctgta ctatatggct caggttctac
     1201 caaatttgta aatgataaca aaatactata tgcaaacgta ccccaacgtt ttgaagcagg
     1261 atacccagag tattttggaa ctcttgcaat gggaaaagca ctgaacactt taaataaaat
     1321 tggtctaaac agaatttcaa aatacgaaag agaattattt ttatatgcta aagaagaaat
     1381 gagtaaaata cctaatataa taatatatgg agataaatca aataatgtaa ttatcccaaa
     1441 tatatctttt aatataagta atatgtatta caaagatgta gcaaaatatt tagttgataa
     1501 ctttggaata gaaactggag ctggagtagt aggtgcagat atttatgtac aaaaattatt
     1561 aggtataaat ccaaaagagg catacgtcag atttatgagg gaaaatcctg taggtcttgt
     1621 taggataagc ttaggaatgt acaatacttt tgatgaggtg gatagcttta tacatgctat
     1681 taaaactttg gcttttaaat aagctttttc tattcttttt tatcaataaa tagagagtag
     1741 ttttgttttc acaaaaaagc aaattatatc aacagtcaat ttcattagca attagacact
     1801 catttgtaac tatacaaact attttacact atacaaacaa aaaactcatt acaatgagtt
     1861 tttttgttta tatatgagat ttattttaat tacttcaatt tactttaatt acatatatga
     1921 ttcaattttg ttttttaaat tctccttagg cataaaacct attaatctat ctacaggttt
     1981 tccatcctta aatattagca tagttggtac tgtagatact tcaaatttct gagctaattc
     2041 tatactttgg tctatgtcca ccttcaagaa gtttgctttt tcaaccatct catttcctaa
     2101 agcttcatat attggtgata gcatcttaca aggtccacac caagtcgcaa agaaatctac
     2161 aactactaaa ccatctttat tttctacttc atttataaat tcattattat ttattatttt
     2221 taccataata tacatctcct ttattatctt cttgatatta atatactacg ccctatataa
     2281 cagttcaatt aggcactttt ttgtaaccgc ctatttttaa taggtttaat attatgataa
     2341 atagatttat aagattaaat atttataaga ctaaatattt ctaatatatt ttattttttt
     2401 cttaatatag ttgacatttt ttcccttaaa ttataaaatc aaattaataa ctacataggt
     2461 agttactaat cttttatcaa aggagtttct atatggataa tataattaat gaattacaaa
     2521 atataggatt tactaaatac gaatctcaaa tatacatatc attattaaag gaaagccctt
     2581 taacaggata tgaaataagt aaattatcag gtgtaccaca atcaaaagtc tatgaaaata
     2641 taacaaagct attaaacaat aatataatta tcaatgttgg aactgaccct attaagtaca
     2701 taccaataaa ccctaatgaa ttattaaaaa ataagaaaaa agaatttgac aattctatgg
     2761 ataatctaaa gaatagctta cagatattaa ataaaagtaa aagtgtagaa tatgttttaa
     2821 acataaaagg agaaaaaaat atattaaaaa aagcaataga aatgataaaa aatgcaaaac
     2881 aagaaattat aatttcttgc ccttatgaag aaattcttga attaaaaaaa gaactcctaa
     2941 ttgcttacaa aaaaaatatt aatattgaaa tactactttt agaaaacaaa agtctgaaag
     3001 gtcttgataa tattcatatt catggaggta ataaaactac acttgaaaat aaaatgcttt
     3061 acaaaggaat tattttgatt gtagataatg atgaaatatt gacaggaaac ttatcagaag
     3121 gcagtgaggc catttcaatt tggacaaaaa actctaacat tttatatatt ggagttcaat
     3181 acataaaaca tgaaatttat atttcagaac aaataaaagg aggttataaa aatgaacaaa
     3241 attaagatta aacaagttga tgcttttaca actatacctt ttggtggaaa tcctgctggt
     3301 gtcgttactg atgcctctaa catttctgat gaaattaagc agaatgtggc taaagaaatg
     3361 aatttatcag aaactgcatt tgtttcagag tcaaatattg cagattttaa agtacaattt
     3421 ttcacaccag gtttagaagt tgatttatgt ggtcatgcaa caataggtac tttccatgca
     3481 cttttggaag aagggaagct taatactaat aagagtatat tttatcaaga aacaaaagct
     3541 ggtgtattat ctgtagagct taagaaaata aataatgaaa atatatttat gatggaacag
     3601 aatacacctg aatttgaaaa tttagataat tgcagaaaag aacttgcaca aatgataggt
     3661 gtgcatgaag atagacttct tgaatatcct attataaagg taaatactgg actttggtgg
     3721 cttgtatttg gtctaaaatc tttagatgat ttaaaaaata tctctccaga tttaaataaa
     3781 atcaaaaaat ttagtggtga taataatata attggtataa ctccattttg tatagaaact
     3841 atagataaaa agtgtgacta ccatttaaga tctatagcac catatgttgg agttacagaa
     3901 gaccctgtat gtggaactgg gaacgcttgc gtatcatctt atatagtaca tcacaatatt
     3961 ttagataaaa ctagttttat tggtgagcaa ggtaacttta taaacagacc tggaaaggta
     4021 tatgtaaata taactagaga aaacaatgac ataacttctg taaaaattgg aggaagtgct
     4081 tatactgttt taagtggtga aattatgtat taatcccata cctaataaaa acaaataaaa
     4141 atactagcta actaaagcta gtatttttat ttgttatttt tatttaataa tcatactcta
     4201 acaaatatta taattatata tatcataata ttgtatttag aagtaaaatt ttatttttat
     4261 tattaattag ttataaatca atctaataca acataattac agtagattaa cctataaaac
     4321 ataataattg cttactaatt atttatcatc ctcaacaagt ctacttaatg tcttatcaga
     4381 taagaataat aatatcgctg caacaaatag tattactgga attatagtat atactttaat
     4441 catatcaaat ttaagagtaa atgcatatat atatccatat cctttaccag ctataaaagt
     4501 agcaaatgtc catactccca taagaacacc tagaagcttc ttaggtgcat acttacttac
     4561 aaaagagtta ccaagtggtg agaataacat ttcaccaaga cttaaaagaa taccaaacat
     4621 gattatccat agtatactag ctttagcagt ttcaggagct ccaactcctc ttgaaaattc
     4681 tgcaccaaca agcattaaga atgcaagacc taagaatatt aatccaagac ctgtcttttt
     4741 aaataaactc atatctcctt gtggtctact agcaagttta aaccataatg ctccaagaac
     4801 tggtcctaat actatacata caagtgaatt taatgagtca aaccaagcaa gaggaacatc
     4861 aaatcctcca acattcatgt ttacaaatgc tgcaccataa tcataaactg caagataagt
     4921 tagataccag aatacccaga aaattacaga gaagaatgat ataagtataa tagcccaaat
     4981 tctcttctta tccatgcttg taagaggaga cttatctttt tcttcaattt tttcagcaac
     5041 tacaccttct ttaaaaggtc tctttcctgc attcccaagg aatctccatc catatatgaa
     5101 ccatattgca cctattacac aaagtacagc tgctataaag aaacattgag aaaatccaag
     5161 tacaccattt tttgcaaatg ttttaaggta aagaatacca actgctatag taccaataaa
     5221 agaacctata ttaacaaaag aatactgtac tgaaaatgct gtatcaagtt cttcttgact
     5281 atcaaaaagc tgtccattta ccgcagatac gttaccttta aagaatgcag taccaattga
     5341 aactaagatt atcattgcat ttaccataga aactgtagtt gcaatagaac caagatagta
     5401 tcctactccc atgataagca tacctatagg tatagtatat ctagctccta tccatctatc
     5461 tgatatatat cccccaatta taggtgcaag gtatgtgaat gcaacaaggt tggcttgcat
     5521 tatagcagct tgtcctttat ctattccaag accaccatga actatagctg ttgtaaggaa
     5581 tatatatatt aagtactttg aagcataata tgctgctctt tcaaatgaga aagttgttga
     5641 gcagatataa aatcccatag gaaatttacc cttctttttt actgttgagc tcataatttt
     5701 aaatcctttc ttaattgtat ttttattttt tacgttttgt ccaaattctt tcttttatga
     5761 aagatataat attattattt tgtaaaacaa tttgtaatta ttattaagat aattgcgcat
     5821 ttatttgtag agtacatatt ctcatggaat aaaattaata cacttcttaa tcataaattt
     5881 aaattatata aattcactat tttcagatat agttataaat taatatattc tcatctaata
     5941 ccatgaaaaa accttcgcca tatgcaattc ttatttttta cgtgatagta ttttacaaac
     6001 taaaatcccc cttttgtagc aacttatgta attacatttt agtgcttttt taaaggagtc
     6061 tcgaataaag caacatatat tttgttcaaa taatgttttt atttattttt taaatttata
     6121 tattacttca cccaaccaat tctcaactta aataactaaa ctactatcta ttcacagatt
     6181 aggcttattt cttacacatt agtttataat aaacactgtg aatctaaaca taaaaactgt
     6241 tattttaaag taattaccca tatattcgct ttgatactat ttattgaggt tatactcttt
     6301 atgtataata tattatttat aaaatacctc aaaatatatt attcataaaa tacctcaaac
     6361 tgaaaacttt ttcacgaata tttatttttc acctcccctt ttttatttca ccatgtaaat
     6421 cgtaccataa atatgcactt atatgcaaga aaaaaatcta ttaatcgaca gtaaataatt
     6481 agaaaaattc aaattatatt tatcaagtat attatataaa atatttccta tgaaaatata
     6541 aattaaatta atgttcagaa ttgtttttag atatgaaatc ttgatttttt tattacttta
     6601 cttatttgct caaatatatt tttgtatgca gtatataata atcaaattat acacttctta
     6661 taactgcatt gatttgaaaa taatattaat aattaataga ataaaaaatt taaattaaat
     6721 ttaaaaaaat ttgttaagtt gattgaatac ttttttatgt atttaattaa ttttataaat
     6781 tcaattattt tctaaattta ggtatgcttt actatataaa aatgattttt tatcttaatt
     6841 ttctaaatat aagtgaatgc tatcatttta agtatcttat aagcaatgta actatatatc
     6901 tctaataact acttttttaa catgcttaaa ctatttataa gctattatat ttatgtatta
     6961 acctaataac tttttcacta aaaaataaca atctattcaa agataaacta tagtacttct
     7021 tctactttgt ttcaataaaa tactaaataa atttcgtaca ttcacaattt ttcaggctac
     7081 actataaata tacaatattt atcttagtta taagtttaag aatattttta gtcttatttt
     7141 gtcgaatatc tttttaataa aacttcataa ttctaagcat atttttacac tgtgttttca
     7201 tgtacaaaaa taatgcttac aaataaacaa cataaataaa acttaaataa gatggattct
     7261 attcaacata gtatccatct tattcattca aaacctaaaa ggatttttta taatattata
     7321 tattttaaaa tctaagtaac tcattatagt atcaatttca cttaaagctt acaatacact
     7381 tattaatctt gttttatatt aaaaacatct acaataacaa tttaaatctt taagtgatat
     7441 ccatctcaca cctaaaggag taggctctcc gcactattct gtaattcttc aatacaatca
     7501 ttattatttt ttatataatt taattatata ttttatttta ccaaaaccag catacataaa
     7561 taatacttaa aatagattaa ataaaggata ctaaaacact ttattgaggt atatgacttg
     7621 aaatatatga actaacttca ttaggagaaa tatctaaaat agttgcaaat tcttcattta
     7681 ataacctttc agcttctttc attatattat catctgcttg atgtgttttt ttaccaatag
     7741 attttacata ctctctgtta ttatctatac ttcttactaa ttttattaac tcttcacatt
     7801 taccacctct gagtattttt ttaaattgct cacttctcaa tttttcatta tctatccatg
     7861 atgtatccat attaggaata tcatttatta atgaaagcac attaatttta gaaagtaact
     7921 ttctcattgg tactttttca ttatctacag gaatttttat tactgtatta ttagaataaa
     7981 taggactcaa tacataatac tcttttttta ttccatttgt aaatcgttca tttgttatat
     8041 ccatgacttt gcagactcct gtcataccat acattatata atcatcaatc ttaaacaaaa
     8101 acatcaccat ccttaataaa aaaaatagtt ttgacaacta aatccacctt gccaaaacta
     8161 tctgctatat attatatttt aacacatttt aagacttaaa tgtaagtaaa acttatatta
     8221 ttaaaattaa aaaatacatt aaccattgat taatgtattt tttagatttt tataacaagc
     8281 atatcaaaat aaattaataa agcttatctc ctgtgaatac ctataaaatt ggtgcttggc
     8341 tattcattga gtacccatca tttcttacat catttatttc taatatttca tcatttgttt
     8401 taaccttagt aagtttttta actgctccat aaggttcttt taatgaaatt ttatctcctc
     8461 ttccagaaat aacccataaa attttatacc ctctaggtat tacttgtagt ttattttcac
     8521 ctttaccatc agtaaagtag actaacaaat taatcttttt attattcgca tactcaaaga
     8581 ctggagaaaa tctagtgcct ccacctatcc taattctatc ttttatatct ttttcagttc
     8641 tcactttata tacacgtcta atttcattat cacattctat aattgtaatt tcatgattat
     8701 agtttttcac tatactaaga acttctttaa tagcttgttt aaactcttca tcactaatac
     8761 ttccacttac atcaagtgca actgctattt ctgacttatg acttctaagt tctcccctca
     8821 aatctaaacg atttggttgt cttctatttc ttcttgttat agtcttcttt ttattatttt
     8881 caactgttcc cattattcta ttaagatata aattccatgg caattcaccc ttactatttt
     8941 taagtgatga tatcatactt tctaaataag caggaacttt acctttttga gaactgttaa
     9001 taaatttttc agtaaattct ctaagggtat tttcatctat ctcattggat tcatcccata
     9061 tatcatgagt tctttcgggg ctataatcaa tttctatatc tccatattta tcactatcat
     9121 cttcctcacc atcttcatcc acttccatca aatctaattc agtctgaatc ttttctacat
     9181 aatattcaaa aggttcatat ggttcaagtt ttaaggaata ctttaaattt acccactcta
     9241 aggtagttgc atatggtggt aaattgttta gaaatttatt tactactata tccattgcca
     9301 tattaattgc taatgtacta tactttcctt ttaactcctt tgctctcatc aaatgcatag
     9361 ataatatatg atgaatttca tgtttaattg tagtctccat ttgctttatg tcaagcgtta
     9421 aaaagattat tggattaaaa tatataacat atttagctcc cttaaaattc acacctgtag
     9481 gactacttat atcaaatctt atttctcttg acatctgaaa caaaaaatat ccataaaaat
     9541 tatcttcttc ttccataaga cttaaattca ctttatctac aagactaaaa aactcatact
     9601 taaaatcttg tggtatatct atatcaaatt tctcattagc acgatttgcc tttagcatag
     9661 aatgagtatt tataatttca cttgctttat tataaagctc ttttgcttgt ttatcaaaat
     9721 aattttccat acattatccc cttattaaac tataagattc aaaatatgat tttacaaact
     9781 cttcattttc tatagctttt ttatatactt caatataact gtttctaata tccttcataa
     9841 tacctatcat taaatctaca ggatacattt ttaaaaattc aataaatcta ttaatatagt
     9901 ggtttgattc atatttatca ttcttaatat ttaattctaa gtcttttaga atgttcatag
     9961 ctgatagata aagtcttgta tgactctcat tttttactct ttctacaata gactcatcaa
    10021 tagattctcc taaaaaaaca tcttcatagg atattaatgg ttcagagttt gattcaataa
    10081 aacttataaa ttcttctgca ataactttac ctacattacc ctttacaaca tttaaaaata
    10141 ctgctctagg aatagaatta tttttttctt tataaacttt ataaatttta gatactctct
    10201 cataacttct aggagtggct cttacatcat cttcatttat tttatgcaga tattctggaa
    10261 aagtggaaat aaactcgata acttttcttt caataccctc atctattgcc cattttatcc
    10321 attgtgtatg gtcactctcc atatttaacc aaacaaacct attttcttgg gctgcatcca
    10381 tatctaccac ttgataatca aaatctgaac catatttact tgatggattc attgctgcta
    10441 aaatctttac atcatcatgc agtttatatc cattaatttc tctatttaaa attaaattca
    10501 taagttcttg ctgtactgta tgctcacaac gatttatctc atctataaat aaaagaactg
    10561 tcttactttt agatatctct tcatcaattt ctcttaattt gttatgaaca gcatacactg
    10621 ttgttttctt ttcagtctta tatccattag aattaactcc tacataagat tctatagttg
    10681 gaagaccacc tatttcaccc tctttaagta agtttccatc aataacaatt aaactccaat
    10741 cattttcttt ggcaagctta tttgctaaag ctgtttttcc tattccactt tcacctacta
    10801 ttaaaggtac ttctccagtg gataatatta agtcaacgct ttttaatgtg tctataaaat
    10861 tcatttttct ctctcctaca taatctttaa tttctcatct acagctattt tttttgctgt
    10921 cttacttcca tatttataaa taaacataat tttatctatt ggtatacttt cgctatttct
    10981 atctataaca ctacaattca aaaaatctct aatatacttt tcctcaacat cttctttgga
    11041 taatacttct tttaatacac tctctaattc atctttagat acttttttca gaatgtactt
    11101 aatcactaaa atattcactt ttaaaaattc caacatttta tttttatcta aatcagttat
    11161 aaagctaata gctgcttcat tattttttat agctataagt tctgcattgt aactaggtga
    11221 atctatatat ctcaaggcat cataacttat tctcactgcc tcctcttgta cactttcata
    11281 aggttgtttt ataaacttta tcgaatcata attttttctt actgctaata gttgtaattc
    11341 ttcacttgga tttttagcat atttaattgc ccatcctgct tgatttatag ccatttcaat
    11401 aactttatca gttgggtttt tgatataatc cagtatactc catccctcat ttactgcttt
    11461 tatcatcata tcttctgttg gattatctat aaatttaatt gctctaatat tattatctat
    11521 tgctagttct tgcatctctc tggttggatt atttatatat tctagtacaa gcccattttc
    11581 tttaatagct aacaatttca tttcatcagt tggattatct attgtagcta taatattggg
    11641 attatttttt atcatttcaa taactctcaa tttttccata atgtgccttt ccttctataa
    11701 ttatttttat atct
//
LOCUS       DAEOTL010000108        11692 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEOTL010000108 DAEOTL010000000
VERSION     DAEOTL010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11692
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.109"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            161..1147
                     /locus_tag="KRH82_003422"
     CDS             161..1147
                     /locus_tag="KRH82_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBG8656679.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1316..1464
                     /locus_tag="KRH82_003423"
                     /pseudo
     CDS             1316..1464
                     /locus_tag="KRH82_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1483..2964
                     /locus_tag="KRH82_003424"
     CDS             1483..2964
                     /locus_tag="KRH82_003424"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBG8656680.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENLYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NDGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            2990..3961
                     /locus_tag="KRH82_003425"
     CDS             2990..3961
                     /locus_tag="KRH82_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBG8656681.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            4423..7470
                     /locus_tag="KRH82_003426"
     CDS             4423..7470
                     /locus_tag="KRH82_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBG8656682.1"
                     /translation="MKKILKRLCTGFLAFATVVTALPSSTVHASNTQYWTESKERVGI
                     VEQVMNDGSISSTFNEGHLTVEGKDAYCIDINTAFKNGYKTRTDASSRMSADRISDVA
                     LSIEYVKQYTDSHSGISSKHAYLLRQLVVWQRLSVQLDWQCDNVRASYDEIPKAVQDE
                     VFAGAKAFVKENKGRYDCGGYIYSGEGQELGQFWAKLAVGNAKLQKTSTNANITDGNG
                     IYSIAGATYGVYSDKDCTKQLATLTTDTSGNTEAVEVRATTVYIKELSAPAGFKIDKT
                     VYSLSVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKSNPQGNASLEGAEFTWNFYA
                     GYYNKNNLPAQPTRTWVTKTIAEKDSDGAIHYITRLANAYKVSGDSFYMQDGKNVLPL
                     GTLTVEETKSPSGYLLEGAYMQGDGSEEQIKGIYLTQITEDGDLAVLSGSNQYHVSDK
                     VIRGGVKIQKRDLETGDTKAQGGATLKDTTFEIISLNDNAVLVEGKLYKKNEVVKTIY
                     TDIEGIASTSADLLPYGKFRMSEQKPPEGYLTEGAKEIDFEITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGSHKRLADVPFRITSKTTGESHVVVTDDNGQFSTASDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALLYDTYIIEELRCESNKGFKIIPPFEIVISRN
                     KVVVDLGTLTDEYEKEITIHTTATSKDGEKTILAGNDVTIIDTVKLDGLVKGTKYQLK
                     GWQMLKEENAELLVGGKRVESDYTFVADDEAMKVEIAYTFNASALGGKNLVTFEELYD
                     LSNPEEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGKKEIEAGKDVTIVDTVK
                     LEGLEVGTKYQLVGWQMLKEENAELIINDKKVENDYTFTSDSETMEVKIAFTFDASAL
                     GGKQFVTFEELYDLSNPDKPIKVTEHKDIEDDGQTVTIKEVPETPTPEEPEKPTTPDT
                     PTKTDSPKTGDNTNILAFAIMMFVSAGGLAGTYFFKRRKMKKS"
     gene            7692..8015
                     /locus_tag="KRH82_003427"
     CDS             7692..8015
                     /locus_tag="KRH82_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8656683.1"
                     /translation="MELKYIVPNVAQTFGNLEFAGENKVDQQRINGRYTPVSRSYNLY
                     SDIQRADDIIVVLPAKAGEKHFKPEQKVKLINPRITAEGYNVKGRGFTNYILMADDML
                     PAESK"
     gene            8030..8443
                     /locus_tag="KRH82_003428"
     CDS             8030..8443
                     /locus_tag="KRH82_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8656684.1"
                     /translation="MRLANGIVLDNEKTFGVLKFSALRHEVRVENEDGTTSDEIKRRT
                     YDLKCSVQERMIQVSIPADVPVKDFPYNAEVELINPVADTVANANFRGADVDWYIKAD
                     DIILKNKGNQPAGNPQNNNPQNLAPQGQQKNKLAN"
     gene            8524..8982
                     /locus_tag="KRH82_003429"
     CDS             8524..8982
                     /locus_tag="KRH82_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBG8656685.1"
                     /translation="MKFKNPMLVVTDIDKSVEFYKKVFGLRVIMDFGANKTLTGGLAL
                     QTSETYKEFIGTSDISFGGKNFEVYFEEDDFDKFADRLKEYDIEYVHPIIEHSWGQRV
                     VRFYDPDKHIIEVGENMKIVCKRFLNSGMTPEQVAERMDVPMKFINACMR"
     gene            9046..9459
                     /locus_tag="KRH82_003430"
     CDS             9046..9459
                     /locus_tag="KRH82_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBG8656686.1"
                     /translation="MLDKIPNAEEMTALVGQSLYAIWNKLCALIDEKYDMECLWNKGG
                     KAWTYEYKYRRGGKTLCALYARENCVGFMIILGKDERLKFDTDRNSYSKEVQKIYDET
                     KTYHDGKWLMFEPTDTILFNDLVKLLGIKRKPNRK"
     gene            9514..10116
                     /locus_tag="KRH82_003431"
     CDS             9514..10116
                     /locus_tag="KRH82_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8656687.1"
                     /translation="MDKVVIYIHGKGGNAEESSHYKPLFSDCDVVGLNYTAQYPWEAK
                     EEFPSLFDLICKHYKSVQIVANSIGAYFAMNALSDKQIEKAYFISPIVNMEKLIADMM
                     YWANVTEDELRDKKEIKTTFGETLSWEYLCYVKENPTTWKIPTNILFGEKDNLTSYAT
                     ISEFTKQTNATLTVMRNGEHWFHTEEQMKFLDEWINKSAR"
     gene            10177..10719
                     /locus_tag="KRH82_003432"
     CDS             10177..10719
                     /locus_tag="KRH82_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBG8656688.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNYCGGCGNGNQSCRIAKC
                     SLEHGQIEYCYECKQYPCEKYQHIDDYDSFITHKRRKADLERAKNIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQGAMKQIQSNDELTLLPFKAQCLYVV
                     EVFQKIAERRNIKLKLIKKK"
     gene            10755..11282
                     /locus_tag="KRH82_003433"
     CDS             10755..11282
                     /locus_tag="KRH82_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcxB family protein"
                     /protein_id="HBG8656689.1"
                     /translation="MTNGGIPLETVELRFQYTQSEYIKAERQYLISSKTIHKYDIALV
                     AVFLLLSVVYMLFSSFSVFSILIFGLIIVVTALGSYLYILMPILKFKQTAKYHEEYTL
                     VFSKENIKFKTQSIDSEVKWDIYSALWESHDFYYLIQAPRLYTLIPKRVFKDLNEKQL
                     FEEIAQSRVKTTKHI"
     gene            11393..>11692
                     /locus_tag="KRH82_003434"
     CDS             11393..>11692
                     /locus_tag="KRH82_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8656690.1"
                     /translation="MRIIWNKGHRIRASDKNLVYRFSLGTLLIVFVAVLLLLNIKQLI
                     RTDWEHFSLLDNGLTLSPYNFITILIATGVCALVAFLYYRFCYDNFKKLLHRQKLA"
BASE COUNT         4471 a         1659 c         2291 g         3271 t
ORIGIN      
        1 aaaattacaa ttaatttaat gttaaagact caattatttg gatgtggaat ggatagtaca
       61 agtagtatat aaaaagtatt gactggacaa ataactatat tttattttaa atatataata
      121 taatgtaata aaatatatca aatgtagaag gtgataacct atgaaaaaaa taacaataaa
      181 tgatattgct aacttggcag gagtatctaa aagtactgta tcaagatatc taaacaataa
      241 agatatcagt gattctacta aagagaaaat aaagacaata atagatgaat atggatatga
      301 gccgaatgca tttgctcaaa gtttgagagc taaaaaaaca tactttattg gtattataac
      361 accgtgttta gattcttttg taaaatctaa aattatgatg gcaatagatg aagaactcaa
      421 agaattaaaa tatacatcac taattattaa tactaataga aaaataaggt cagaaataga
      481 tagtatatca aagttagcta gtctaaaagt tgatggaata atactaattg gtaccgaaat
      541 aactaaagaa cataagaatg aaattgaaaa gttagatata ccgatagttg tagttggaca
      601 aaaagttgat ggtatcaata gcatagtgaa tgatgattat ggagcaggat ataaaatggg
      661 tcaatatatt gctaataaag gttacaaaaa cattgtatat ttaggtgttg atgaaagtga
      721 tatatcagtt ggtttaaata gaaaaaatgg agtacttaat gggttaaaag ataaagggta
      781 tgatgcaaaa gtattttata ctgactttga ccaagaaacg tctatacaaa gaagtggaga
      841 aatgctagaa agtgaaaatc cagatataat aatatgtgca actgataata tagcaatagc
      901 aacaatgaaa gaaatcaata agagaggtaa aagtatacca caagatatat ctgtagctgg
      961 atttggggga tatgatgtat tgtctattat aagccctaaa cttacaacaa taaagtttga
     1021 aaataaaaat gcaggtaaag tagcagcaaa tacgatagta aacttaatac aagaaagaaa
     1081 agaaccacta ttaaaggaga ttaaatttga attaatagaa ggtgaaagta caataaataa
     1141 aaattaagat acacattaca tatattagta atgtgtattt ttttactaaa aaaactataa
     1201 ttctaaaaat taggaaaact tttttgaaag aaatattgca tctgaaataa atttatgcta
     1261 atctttaatt aaaccggttt cgaaaccggt ttaattaaac cgatagaata gcaaaatgag
     1321 tgcaaaaata actgattgta acaaagtatc aaagtaatta ttggagtaca taggaataaa
     1381 caaaatataa aagatgtagc acattgtgta ataagactaa gaattgtttt agatagcaat
     1441 aataaagcaa atataaaatt ataaaagaaa aggaataaaa atatgtacaa agagcctaaa
     1501 tatagaacca tattagaatc gacaaaagaa gaattaaata aattaagaaa tatatcttta
     1561 aatgataaat ataaaccact atttcatata catccacaac atggactact taatgaccca
     1621 aatggattag catattataa tggtaagtat catgtatttt atcaatggta tccatatgat
     1681 gcaactcatg gaatgaagca ttgggcttat gtaagttctg atgattttgt aaactggaat
     1741 agagaagatg tagcattaat accaatcgaa agttatgaat ctcatggagc atattcaggt
     1801 aatgcgatag aggtagatgg aaaattgcat atgtattata cagggaatat aaaatatagt
     1861 gcagaagata gatatgcata tcaaaactta gctataatga acaaggatgg taaaataact
     1921 aaatatgaaa ataatccaat agtaagtgaa ataccaaaag gatatacagg acatgtaaga
     1981 gacccaaaag tatttaaaag aaaggataaa tactttatgt tacttggagc acaaacaagt
     2041 gataaaaaag gagttataat agtatatgaa tctaaaaact ctatagattg gaattttaaa
     2101 ggagaattaa atgtaaaaaa catagatgaa gattttggtt acatgtggga atgtccagat
     2161 tatattaata tagatgaaaa agatatatta atattttcac cacaaggagt agaacctaaa
     2221 ggatttgatt atcaaaatat atataatgta gtatatgcta ttggtaatat ggatttagat
     2281 aatttaacat ttgaaataga tacaatgaaa gaactggaaa aaggatttga tttctatgct
     2341 ccacaaacat ttataaagga ctcacaaata atactatttg catgggctgg aatgggagaa
     2401 gttttatacc ctacagataa aaacaaatgg gcacattgtc taactgttcc aagaaaatta
     2461 aatataaaaa ataataagct attgcaaatg cctgtagatg aattaattaa attaagatat
     2521 gatgaaacaa gtgggcaaaa tactataaag aataatatca atattataga aaataatgaa
     2581 aatttatatg agcttaatat taatataaaa aatattgaca gcaataaatt tgggctggaa
     2641 ttattttcat cacaagatga aggtgtaaaa ttagaattta acaaattagg aaacattgta
     2701 actttagaca gaagcaactt taaaaaagtt ttcggtgttg aatatggaac aaatagaaaa
     2761 gaatatataa atattgatga aaatactaat atcaaagtac tagcggatag aagtatttta
     2821 gaaattttta taaatgatgg agaagtagta tttactagta gaatatttgc taaagaaaat
     2881 tctaatcaaa taagggttta tagtgataaa atagtagagt atgagtatac taaatttaaa
     2941 ttaaagcaag gtattgaatt ataaaaacac attataaggg gtagaaaaga tgaaaaaagt
     3001 aattagcata ggagaagctt taatagactt tataccgaat caaaatggtg gtaaattaaa
     3061 aaatgtatca gaatttagaa gagtagcagg aggagctcca gcaaatgtta gtgctgttgt
     3121 agcaaagctt ggaggaaaat cgagttttat atctaagtta ggaaaagatg catttggtga
     3181 ttatataata gatgtattaa atgaagtaaa tgtaaatact gattatgtat tgagaacaag
     3241 taaagcaaat acaggacttg cttttgtatc attaaaagaa gatggtaatc gtgatttctc
     3301 attttataga aatccaagtg cagatatgct tttagaagct gatgaagtta aaaaagagtg
     3361 gtttaataat tgtcatatcc tacatttttg ttcagtagat ttaatagata gtccaatgaa
     3421 attagcacat aaaaaagcaa tagaatacgc acttgaaagt aatagtataa taagctttga
     3481 ccctaatata agattacctt tatgggatag tgagcaatct tgtaaaaagg caatatcaga
     3541 atttttacct tttgctcata ttgttaagat atctgatgaa gaattagaat ttataacagg
     3601 agaaaatgat atagaaaaat cattacataa actctttgtg gggaatgttg aactagtatt
     3661 atatacaaaa ggaaaagatg gagtagatgc atacactaaa aaagtaaaag gtatgtgtaa
     3721 aggggttaaa gtaaatgcaa tagatacaac cggagcagga gattcttata taggttcatt
     3781 tttatacacc ttattgtata aacaaataac attgaatgat ataaaagaaa tgaaacaaga
     3841 aacgttaaat gagtatttag aattttctaa ttattatgca gctcgtagta caactattaa
     3901 aggtgcgata agttcatatg caacaaagga agaaataact gaatttataa aaaatttata
     3961 gtaggaatga gtaataggtt ttgaaggaag taacatgtaa agagttttta aggatgttta
     4021 ctatgaaaat aattaacata taaaaagcaa taaagaggct gtctcaaaat agagataagc
     4081 ctctttatca ttgttgaaat gataaaaaat attttaatta ttgttacttt ttagaagaaa
     4141 aacacactaa aaatttgatt atccgctaaa acgctgtatc tatcggcatt atcaaggagc
     4201 taaacacatc aaaatactac taatttacta cgattgaatg agccttgata cgtcctattt
     4261 cccagatatg caaagatacg gtacagcaca tcagtattga aacaagaaaa attgaatact
     4321 tcatagacta cggaacgcac aatatcagcg ttccttttct atttccagcc gttcctagtg
     4381 gacggctatt ttactaccaa aatgaaagga gcatttagaa ttatgaaaaa gatattaaaa
     4441 cgattgtgta caggctttct tgcctttgca actgtcgtta ccgctttacc gagttcaacg
     4501 gttcatgcgt ctaatacaca gtattggacg gaaagtaaag agcgtgtcgg tatcgtagaa
     4561 caagtaatga atgacggttc tatcagttct acctttaatg agggacattt aaccgttgag
     4621 ggcaaggacg cttattgtat tgacatcaac acagcgttta aaaacggcta taagaccaga
     4681 acagacgcaa gctcacgcat gagtgccgac cggataagcg acgttgcctt atctattgag
     4741 tatgtgaaac agtacacaga cagccacagc ggaataagca gtaaacacgc ctacctatta
     4801 agacagcttg ttgtctggca gagattaagt gttcagcttg actggcaatg cgataatgtg
     4861 cgagcttcct atgatgaaat cccaaaagcc gtacaagatg aagtattcgc aggagcaaaa
     4921 gcctttgtta aagaaaacaa aggacgttat gactgtggcg gatatatcta ttctggcgag
     4981 ggtcaagagt tagggcaatt ctgggcgaag ttagctgtcg gaaatgccaa acttcaaaag
     5041 acttccacca atgccaatat tacagacggc aacgggattt attcaatcgc tggtgcaaca
     5101 tacggtgtgt attctgataa agactgcacg aaacagcttg ccacccttac gactgatacc
     5161 agcggaaata cagaagccgt tgaagtaaga gccactacag tatatatcaa ggaactttct
     5221 gcaccagcag gatttaaaat tgataaaaca gtttactctt tatctgtgga agctggaaaa
     5281 acagcgactt taaaagtatc tgatacacca aaagtaacag ataccttgat tgagctattc
     5341 aagattgaca tggaaacaca gaaatccaat ccgcagggaa acgcttcttt agagggagca
     5401 gagtttacat ggaacttcta cgctggatat tacaacaaga ataatcttcc agcacagcct
     5461 acaagaacat gggtaacaaa gactatcgct gaaaaagaca gcgacggagc tatccattac
     5521 attacccgtt tagctaacgc ttataaagta tctggggaca gcttctatat gcaggacggt
     5581 aaaaacgtgc ttcctttagg aacactaacc gtcgaagaaa caaaaagtcc gtctggttac
     5641 ttattagagg gtgcatatat gcagggagac ggtagcgaag aacagataaa aggaatatat
     5701 ctgacacaga ttacagagga cggcgacctt gccgtattgt ctggaagtaa tcagtaccat
     5761 gtatcagata aagtcattcg tggcggtgtg aaaatccaaa aacgagattt agaaacgggt
     5821 gacacgaaag ctcaaggcgg tgcgactttg aaagatacca cctttgaaat catttcctta
     5881 aatgataatg ctgtcttggt tgagggcaag ctatacaaga aaaatgaagt agtaaagaca
     5941 atctataccg acattgaggg tatcgcttct acttctgctg atttgttacc ttacggaaaa
     6001 tttaggatgt ctgaacaaaa accgccagag ggatatttga cagagggtgc aaaagagatt
     6061 gactttgaaa tcacagaaaa tggaaaaatc gtagatttga ctgacgaagc ccactctatc
     6121 tataaccaga ttaaacgtgg cgatattgag ggcgtaaaaa ttggtgcagg ttcgcacaag
     6181 cgtcttgcag atgttccgtt taggatcaca agcaagacga cgggcgaaag tcatgttgtt
     6241 gtaactgatg ataacggaca attctctact gcttctgatt gggcttccca caagcacaat
     6301 accaatgcag gaaaaacaag cgaggacggt gtgtggtttg gtacttctga accagacgac
     6361 agcaaaggtg ctttgcttta tgatacctac atcattgaag aattacgttg tgaaagcaac
     6421 aaaggcttca aaattattcc accgtttgag attgttattt ccagaaataa ggttgtcgtt
     6481 gatttaggta cgctgactga tgaatacgaa aaagaaatca ctatccatac cacagctacc
     6541 agcaaggacg gcgaaaagac tatccttgca gggaatgacg ttactatcat tgatacggtc
     6601 aaattagacg gtcttgtaaa aggtacaaag tatcagttaa aaggctggca gatgttgaaa
     6661 gaagaaaatg ccgagcttct tgtaggtggt aaacgagtgg aaagtgatta tacctttgtc
     6721 gctgatgatg aagctatgaa agtggaaatc gcttatacat tcaatgcgtc tgctcttggc
     6781 ggtaagaacc ttgtaacttt tgaagaattg tatgatttaa gcaatccaga agaacccgtg
     6841 aaagttgcgg aacataaaga tattgaggac gacggacaaa cggtacttat cacagaacgt
     6901 atcatcaaaa tccataccac agctacggac aaggacggca agaaagagat tgaagctggc
     6961 aaggacgtaa cgattgttga tacggtcaag ttagagggct tagaagtcgg tacaaagtat
     7021 cagcttgtgg gctggcagat gttaaaagaa gaaaatgcag agcttatcat caatgataaa
     7081 aaagttgaaa atgactacac atttacgtct gacagtgaaa ctatggaagt aaagattgca
     7141 tttacttttg acgcttctgc tcttggcggt aaacagtttg taacttttga ggaattatac
     7201 gatttaagca atccagacaa accgataaaa gttacggagc ataaggacat tgaggacgac
     7261 gggcagacgg ttactattaa ggaagtacca gaaacaccta cgccagaaga accagagaag
     7321 ccaactacac cagatacacc aacgaaaaca gacagtccaa aaacgggcga caatacaaat
     7381 attcttgcct ttgcgattat gatgtttgtt tctgctggcg gtctggctgg tacatacttc
     7441 ttcaaacgcc gtaagatgaa gaaatcataa ggcggtaact gcatgagaaa agaaaaatca
     7501 cgctctccgc cgtaacttaa ataggcagac tacttctatt ctggcttgtc tgccgattac
     7561 ctgcaagaac ccagatcgtc aagagtgcgt cagcatacag tttacccttt actgtctggg
     7621 cttgctggta tctcattaac tgccagaata caaaacaatc aaactaatag aaagaaacga
     7681 ggtaaaacaa tatggaatta aaatatatcg tgccgaatgt ggcacagact tttggaaact
     7741 tggaatttgc aggggaaaac aaagtagacc agcaacgtat caatgggcgt tacactcccg
     7801 tatcaagaag ttacaacttg tattcggata ttcagagagc cgacgacatt atcgttgtat
     7861 tgcctgcaaa agctggcgag aagcatttta agccagagca gaaagtaaaa ctgattaacc
     7921 cacgcattac cgcagagggt tacaacgtca aaggacgtgg atttacaaac tacattttaa
     7981 tggctgatga tatgttacca gcagaaagca aataaggggg tatttgatta tgagattagc
     8041 aaatggaatt gtattagata acgaaaaaac ttttggagta ttgaaattct ctgcacttcg
     8101 acatgaggtg cgtgtagaaa atgaggacgg aacgacaagt gatgaaatta agcgtcgtac
     8161 ttatgatttg aaatgtagtg tgcaggaacg catgatacaa gtgtcaatcc ccgctgatgt
     8221 tcccgtaaag gactttcctt ataatgcgga agtggagtta atcaatcccg tagctgatac
     8281 ggtggcaaat gccaacttta gaggggctga tgtggactgg tacatcaagg ctgacgatat
     8341 tatcttgaag aacaaaggca accagccagc aggaaatcca cagaacaaca atccacagaa
     8401 ccttgcacca caaggacaac aaaaaaataa actggcaaac tagattttca ttgtagcaaa
     8461 tacaagtgac tgttataata tgggtatgga aacagataat ttgaacttgc ggaggtagcg
     8521 aaaatgaaat ttaaaaatcc tatgttggta gtgactgata tagataaatc agttgagttt
     8581 tataaaaaag tttttggact tcgtgtaatt atggattttg gagcaaataa aactttaaca
     8641 ggtggcttag ccttacagac aagtgaaaca tacaaagagt ttatcggtac aagtgatatt
     8701 tcttttggcg gtaaaaattt tgaagtctat tttgaagaag atgattttga taaatttgct
     8761 gataggctga aagaatatga tattgaatat gtccacccta ttatagaaca ttcatgggga
     8821 caacgtgtag tccgctttta tgacccagat aaacatatta tcgaagttgg agaaaacatg
     8881 aaaatagtat gcaagcgttt cttaaatagc ggaatgacac cagaacaagt tgcagaacgc
     8941 atggacgtgc ctatgaaatt tataaatgcc tgtatgagat aaattcttgt ttgtagaagt
     9001 caataaatac aaagataaat aagaagttat aaaggagaaa tgagtatgct ggataaaata
     9061 cctaatgcag aagaaatgac tgctttagtc gggcaatcat tatatgctat atggaataaa
     9121 ctgtgtgcct taattgatga aaagtatgac atggaatgtt tatggaacaa aggtggtaaa
     9181 gcgtggactt atgagtataa atatcgtcgt ggcggaaaaa cgctttgtgc attgtacgca
     9241 agggaaaact gtgtaggatt tatgattatc ttagggaaag atgaacgatt aaaatttgat
     9301 acagatagaa atagttattc aaaagaagtg caaaaaattt atgatgaaac aaaaacctat
     9361 catgacggaa aatggttgat gtttgagcca acagatacaa tcttatttaa tgatttggtt
     9421 aaattattgg gaataaaaag aaagcccaac aggaaatgat gattttatac ttcaatttag
     9481 tatacaaatc ggaagttgag gaggacaact attatggata aagtagttat ttatatacat
     9541 ggtaaaggtg gaaatgcaga ggagtcttca cattacaaac ctctttttag tgattgtgat
     9601 gtggttggac tcaactatac tgcacaatat ccatgggaag caaaagaaga atttccatca
     9661 ctttttgatt tgatttgcaa acattacaaa tctgttcaaa tagttgcaaa tagcataggt
     9721 gcctatttcg ctatgaacgc cttatcagat aagcaaatag aaaaagcata ttttatttca
     9781 cctattgtga atatggaaaa actgattgca gatatgatgt attgggcaaa tgttacagaa
     9841 gatgaacttc gagataaaaa agaaattaaa acaacttttg gagaaacact ctcatgggaa
     9901 tatctctgtt atgtaaaaga aaatccaact acatggaaaa ttccaacaaa tattttattt
     9961 ggtgagaaag ataacttgac ttcttatgca actatatctg aatttacaaa acaaactaat
    10021 gcaacactta ctgttatgag aaacggagag cattggtttc acacggaaga acaaatgaaa
    10081 tttcttgatg agtggataaa caagtctgcc agataaatcc cagtttgtaa aagtcaataa
    10141 atacaaagat aaatttgaag ttaggagact ggtactatga aaggatttga acgaaaaaac
    10201 caattatttt ctctttgcgg attgaattgc ggactatgcc ctatgctttt gggaaattac
    10261 tgtggcggtt gtggcaatgg taatcaatca tgcagaattg caaaatgtag tcttgaacat
    10321 ggacagattg aatattgcta tgaatgcaaa caatatccat gcgaaaaata tcaacacatt
    10381 gatgattatg attctttcat cacgcataaa cggcgaaaag cagatttaga aagagcaaaa
    10441 aacataggca ttgagcaata taatcttgaa cagcaggaaa aaacacaaat tctttcttac
    10501 ttactttcta actataatga cgggcgtaga aagactttct tttgtgtggc agtcaattta
    10561 ttagaacttt cagaattaca aggagcaatg aaacaaatac aatccaatga cgaattgacc
    10621 ttactaccat ttaaggcaca atgcttgtat gtggtggagg tgtttcagaa gattgctgaa
    10681 aggagaaata taaaactgaa acttatcaag aaaaagtgat tttcaaattt gaaattgtag
    10741 caaagattat ttatatgacg aatgggggaa tacctttgga aacagtagag ttaagatttc
    10801 aatatactca aagtgaatat ataaaagcag aaaggcaata tttaatttct agtaaaacta
    10861 tacataaata tgatattgct ttagtcgctg tatttttgtt gctgtcagtc gtttatatgc
    10921 tgttctcatc ttttagcgta tttagtattt taatatttgg attgataatt gttgtaactg
    10981 cattgggaag ctatttatat atcctaatgc ctatactgaa attcaaacaa actgcaaaat
    11041 atcatgagga atatacgctg gtattttcta aggaaaacat taaatttaaa acacaaagca
    11101 ttgactcaga agtgaagtgg gacatttact ctgcactatg ggaaagccat gatttttatt
    11161 acttaattca agcaccacga ttatatacgt taattcccaa aagagttttt aaagacctaa
    11221 acgaaaaaca gctatttgaa gaaattgcac aatcaagagt taaaacaaca aagcatatat
    11281 aatgaacata ccctacaatg taacaacttc atattcatac acacaaagcg gtcagtcttt
    11341 taagattgac tgcttttttc atacttaaat ttaagattgg agtgattgat ttatgcgaat
    11401 aatttggaat aaaggacacc gtatcagagc cagcgataag aacctcgtct atcgcttttc
    11461 attgggaacg cttctgattg tattcgtggc ggttctcctg ctactgaata taaaacagct
    11521 catacgtacc gattgggaac atttcagctt gttagacaac ggcttgacgc tttcccctta
    11581 caacttcata actatactga tagcgactgg tgtttgtgca ttggtcgctt ttctgtatta
    11641 ccgcttctgt tacgacaatt tcaagaagct cctgcaccgt caaaagctgg ca
//
LOCUS       DAEOTL010000109        11553 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEOTL010000109 DAEOTL010000000
VERSION     DAEOTL010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11553
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.110"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            333..479
                     /locus_tag="KRH82_003435"
     CDS             333..479
                     /locus_tag="KRH82_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656691.1"
                     /translation="MTAYIASLKEYYSFIETQIGDFIKKYGEDVVELCLHRVMILLCE
                     CGLA"
     gene            1311..2225
                     /locus_tag="KRH82_003436"
     CDS             1311..2225
                     /locus_tag="KRH82_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBG8656692.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2615..3262
                     /locus_tag="KRH82_003437"
     CDS             2615..3262
                     /locus_tag="KRH82_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBG8656693.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3429..3998)
                     /locus_tag="KRH82_003438"
     CDS             complement(3429..3998)
                     /locus_tag="KRH82_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBG8656694.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(4003..4902)
                     /locus_tag="KRH82_003439"
     CDS             complement(4003..4902)
                     /locus_tag="KRH82_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656695.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4913..5062)
                     /locus_tag="KRH82_003440"
     CDS             complement(4913..5062)
                     /locus_tag="KRH82_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656696.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(5055..5639)
                     /locus_tag="KRH82_003441"
     CDS             complement(5055..5639)
                     /locus_tag="KRH82_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBG8656697.1"
                     /translation="MKRFFIVVLGCIFVLGMISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            6028..7353
                     /gene="cdeA"
                     /locus_tag="KRH82_003442"
     CDS             6028..7353
                     /gene="cdeA"
                     /locus_tag="KRH82_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBG8656698.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKCRYKY"
     gene            complement(7448..8242)
                     /locus_tag="KRH82_003443"
     CDS             complement(7448..8242)
                     /locus_tag="KRH82_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656699.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8243..9118)
                     /locus_tag="KRH82_003444"
     CDS             complement(8243..9118)
                     /locus_tag="KRH82_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656700.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLSFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSESDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9122..9490)
                     /locus_tag="KRH82_003445"
     CDS             complement(9122..9490)
                     /locus_tag="KRH82_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656701.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9673..10332)
                     /gene="deoC"
                     /locus_tag="KRH82_003446"
     CDS             complement(9673..10332)
                     /gene="deoC"
                     /locus_tag="KRH82_003446"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBG8656702.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIEDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10368..>11553)
                     /gene="murJ"
                     /locus_tag="KRH82_003447"
     CDS             complement(10368..>11553)
                     /gene="murJ"
                     /locus_tag="KRH82_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBG8656703.1"
                     /translation="KQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSIP
                     YNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSLI
                     KLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIVS
                     VMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAFD
                     ARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLVL
                     IKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVLS
                     YFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMTIFKVEEVDMILNIAKRKLHL
                     KK"
BASE COUNT         4060 a         1759 c         1298 g         4436 t
ORIGIN      
        1 aaattaaatt ccttaaaagt atgattaatt ataattatat aagtatattc ttattacact
       61 tatattaatt tatattaaat atctactaac tcaaatattc ataattaaac tttaaactgg
      121 ataaattttc ttttaagaat gaaagtttat ccagttttgc gattataata accagtttta
      181 catatccact tgtaaaatat atctaagcaa tatatcatac tatatagatt tatgagtgaa
      241 ataatatctg ctatttactg aatattttta tttttcgttt tttaggggga ttagttgtct
      301 ttaaagataa gattgatgaa tgtgttcata taatgactgc atatattgct agtttaaaag
      361 aatactattc attcatagaa actcaaattg gtgattttat taaaaaatat ggagaagatg
      421 ttgtagagtt atgtctccat agagtgatga ttctactatg cgaatgtggt ttggcataaa
      481 attaaatgta ttaaaatggg taagaagaat cctatataat attcttctta cccattttaa
      541 tatatcaatt tcatagctta tcgtttaaaa tattttacat ccattactag acaactttac
      601 attctctttt taattctagt atatttaaat cattttagtt gctccttatt tattcttatt
      661 acttgtttta ttttataaat aaaataattc ttcttaataa tgttttttat tgatattcct
      721 atcacacatc caattattta tcattgtctt gaaattgttt gcatacttaa tttaatccaa
      781 ttgaaacacc ccagcataga atcccctgta aaatagaagt tggattaaat cctaacatct
      841 atacagaaaa tactactcca agcacaagca atataatgga atatatttat cacttaattt
      901 tttatacttt ttaaatccca tacctaaaac attaagtgca gctattagaa ttaataattg
      961 ttgtggtata aaattatgct tgcttcatat ttattcattt tttgctataa aagttcttgt
     1021 tttacaaaaa acatttgttt tgtatcaaaa taatacttat aaattacata attctcataa
     1081 aaatttctag tattacttgt actcttaata aataatagcc aacaagtacc ttaaatcatt
     1141 atatctatat ctaataagaa acacagtaag ataatttttt cgcccataac ttaataaaaa
     1201 ctgttgatat tagtagcaat tgaatttagt taatttattt ataatataca taaatttaaa
     1261 tattacgaat aaagtattat aaataggata ctttctaaag ggaggaaatt atgatagata
     1321 atcaaaaata tgttatttta tcactagaat tacatttatt tttttcaaga attatgaaag
     1381 agcatgctct ttttttagaa gcaggattca caaataaaaa ttataatctt gctatggaag
     1441 ctgaccacta taaaaagcaa tttgaagatt tattatcata cactgttagt gctagtaatg
     1501 gtataattag acctgatata ttatattcag aagagcttgt aactactctc acatcagttg
     1561 cagaacaaaa aacagaagag tttacaggga tagaaataaa caaaaacatc actacaagag
     1621 aattaaatct acaaagtggt gtaaacccac aagttggtca agacttagtg aactatgtag
     1681 ctcaacttaa ctctgatgca ataagattac ttgatgggct tattaatttt aaagaaagag
     1741 tcttagatgg tgtactatca tgtactatat ttacatcaaa ctaccctcta cttcttgaac
     1801 atataataca tgaagcaaat ttatatcgtt cttatgtagt tgaccttgaa aataaaatag
     1861 atattgagtc aaaaaacgct aaagaaatag aattattctg ggaccatatt atgatggaac
     1921 atgctctgtt tatgagagga ttactagacc cctcagaagg tgaactaata aatacttcaa
     1981 atgattttgc tataaaattt aatgaattaa ttgaaaaaac aaacgaaatg actgattcta
     2041 atatcaagaa cattacagaa gaaactctaa atgaaactgt tgagtttaaa gattttaaag
     2101 aagcaggagc atcaggaata gaacagtgta agataaaatc tataatatta ccacttttag
     2161 cagaccatgt tttaagagag gcaaatcatt atattagaat attggagagt tataaaaaca
     2221 tgtaattaaa aattactttt aaaataatct ttgcatattt agataaaata aaggtacagt
     2281 taactgtacc tttatttttt ataaacttat aaaatttaaa caagttattc ataaaataaa
     2341 ataataatca tctataaccc acaactttat tttatattaa ataaaaagta ttagtgatta
     2401 tgttttatag gtatttcttt attcagttat ttattaaaaa ctaatagtaa atcttatact
     2461 aatcgcatat ttatgttata actatattgt aactattttc gtaatcttag gaaaaggtta
     2521 cttataaaat taaccttata caataatata tcgtataatc ttaattagca taatagttac
     2581 aatattaaaa tttaaatatg ggagtgattt tagtatgata agacaaacac cattagagaa
     2641 acgatatgac aagctaggtc ctcatattgt aacagcactc aaaaaacgtt attttgatgc
     2701 ttattactgt aaaactagaa atgaagcttt gcaacaaatt ttagatttaa ttcctcaaaa
     2761 tcatgtagta tcatggggag gatctgaaac acttaaagaa atgggcgtac aaactgctgt
     2821 tagagagaaa ggatttaaag ttattgatag agatttagca aaaactccag aagaaagaac
     2881 tgaaattatg cgtcaagcac ttctatgcga tacttttttg atgagtagca atgcaattag
     2941 tgaagatgga caactcttta atattgatgg aaatggcaat cgtgtagctg caatgatatt
     3001 tggtccaaaa aatgttatag ttgtagctgg tatgaataaa attgtaaaaa acattgatga
     3061 tgcaatacaa agaactagaa caattgcatc tccagcagtt gttcagcgtt ttcaagatgt
     3121 caatacacca tgctatatta atggaagttg tatagattgc acaagtcctg aaagcatttg
     3181 tgcatacatg gttactacaa gaatcagtcg tccagcaaaa aaaataaagg taatattggt
     3241 aggagaaaat cttggtctat aaaatataca tacatgtaaa tagctctata aataataaaa
     3301 tcatatgaaa taacttattt ctaaaagtgg tagaataaaa gcttctacaa gactttcatt
     3361 ctaccacttt tatattcttt taatttgtgt ttctatatta ttaattgctc cgattttcat
     3421 atatattact aactattttt attttcataa tttttttgtt cttcatcaag ctgtttataa
     3481 taatctttat tatagtcagc tagataatct ataccacctc ctgtaatcac atttaataat
     3541 ttcattgcag attcttgatt aactttacaa acataattat caccagattt aacaagctct
     3601 aatgtaatat taaattcttt tttctttgca gaatcaatat ctttcatagt tggatttggc
     3661 atcatttctc ctagtttagg aggattcttt tttaaaatag aaaccatatc agtattgtta
     3721 atttttaaat ctacagtcac tttatcctta ttattcttta tatctgaaat ttcccaagtc
     3781 atatttttag aatacatttt aaatccttct ttatcttcgt atataagatt acctaaccct
     3841 gattttggga aatacttatc aacagtatct gcatcttgtg tttttattga attaaacata
     3901 ctatccactt cattttttat cttattatca ttagtacaac cagctaacac cagtactgat
     3961 attgcaaaca ttataataca tataataaat ttcttcatta aattatatcc ccctatactt
     4021 ttttgcacaa atattattct cttttttatc ttttgaaaaa gttgtagtaa ttgcattttg
     4081 tggacaaact tttatacatt caccacacct aatacagtct ggactattta catctttata
     4141 tattggtata tcaagcttac attttgtttg acatgctgta caatttgtac atttatcttt
     4201 atcaatttta aatctatata ttgaaatagg attaaaaaaa ccatagattg ctcctaaagg
     4261 gcatatatac ttgcaaaatg gcctataagt aatgattgac atcaataata tcaatagcaa
     4321 aatacttaac ttccagctaa ataaaaatcc tattgattct cttaaattct catttcctaa
     4381 aataagtggt attcctccca aaagtgttcc tgaagggcaa atccatttac aaaaccaagg
     4441 atttccaccc cctgctacat ttacaatagc aactggcaaa ataattacaa acattattaa
     4501 gactatatac tttagatatt ttagatattt atcaccataa acttttttta tctttactgg
     4561 aaagggtact ttatgtagta aatcttgtac aagtccaaag ggacaaagcc aaccacaaac
     4621 aaatctgcca aaaaaagcac caaatgccat taaaaaacca acaacataaa atgagaattt
     4681 atactctctg cttgataaaa ctgcttgtaa tgaacctatt ggacatgctc caagtgcacc
     4741 tggacatgaa taacaattca atccaggtac acataatttt ttactttctc ctccatatat
     4801 agttccttct aaaaatccat ttacatatcc atttgttaat gctgtaaatg caacttgagt
     4861 aataagtctt atattattat ttactttaga taataacttc attcctcttc tcctaaccaa
     4921 taccaataca ctcaagacaa atcataattg ctttagttaa tactgtattt gtttctccac
     4981 gatatgtacc taatgcaata aatataatac taattgcaat aatagaaatg ccttttttat
     5041 tatctttaat aaaattactc attggctttt accattttta gtctttcatc tataattttt
     5101 ttccaatctt ccttactatt tgcacctaca accttctcac ccacaaagtt tcctttcttg
     5161 tctacaaaat aagttgttgg aaactccata actcttttaa aatcagtttt tttaagttct
     5221 tcagatacag tcaattgttg gtaagttgca tctgactttt tcataatgtc tttaactaaa
     5281 tttttctctt catttgaaag accagttctc atatcagttt tatcaacttc tacaactaat
     5341 ccctttatag ctacattgga attattactc tcatattctt ttgataatgc ttcaagctct
     5401 ggcatttcac ccacacatgg tccacaccaa gtagtccaga cattaataag agtaagttct
     5461 ttatttgaaa atatctcttt tgttacctta tttccatcaa catcctccgt atctaaatta
     5521 ctaaaccatt cactattatt cttgtttttt tctactggct tagattcttt tttgctacat
     5581 ccagaaatca tacctaaaac aaaaatacat cctaaaacta ctatgaaaaa ccttttcata
     5641 tctcacactc ctagaattta tatagtatat aaaatcgctg cttgaaataa aaataactta
     5701 tcttctatat taaagtaatt atatttaata aataagagct aatttaaaaa aagatataca
     5761 gttaaaatct atttcttttc agacaaaatc ttatatatat ataatagctt gtaaatctta
     5821 agattatata catatatttc taaagatttt cttaagaaac agttagattt tactaatata
     5881 agtttattaa ttagcattat actaatttat cttaatatga ttttttgttg attttaagct
     5941 gtttatcgta taaataaaat ttttcttgac tatatagtta ctatatagct tattatatat
     6001 agagagtaat aaaaggaggt aaaatttatg gaaaatttat ttacaagaaa attcactact
     6061 tttgaatttc taaaatttgt ttctcctgca attatatcca tgatatttat atctttgtac
     6121 acaataatag atggcatctt tgtatcgaca ttagttggtt ctgatgctct tgctagtata
     6181 aatattgtac tacctataat taaccttgtt tgtggatttg gaataatgat ggcaactggt
     6241 ggaggtgcta tcgtttctat acgtatgggt gaaaatagac aggatgaagc caactctaca
     6301 ttttctttta tagttttgtt ttcattgatt gttgggattt tattcacagt aatctcatat
     6361 ttctttatca aagaaatatc tattttgctt ggtgcaacag ataagttatt accatattgt
     6421 ataacttatg gtaaagttat gattttatgt acaccatttt atattttaaa atttatattt
     6481 gagtactttg caagaactga tggaaattct aaatttagtt tatttctatc agtcattggt
     6541 ggtgtaacaa atataatatt ggattatgta tttattaaat attttggaat gggtctttta
     6601 ggagctgcag ttgcaactgc tataggtatt attttaactt gtgttttagg tattatttac
     6661 ttcttatcta ataaatctac actaaaatta agaaaaccaa aaaccgattt tagacttata
     6721 agagatacta tgataaacgg ttcttctgaa atggttacag aattatctac aggaattaca
     6781 acattcttat ttaatgtagt agctttaaaa ttagcaggag aaaatggact tgctgctctt
     6841 actatagtat tgtatgctca ttttttaatg acatcagtct atctaggatt cgctgctgga
     6901 gtgtctccat taataagcta taattttggt gctgaaaaca gtgataaatt aaaagaaaca
     6961 tttaaacatt ctctaaaatt tatatttgtt tcttctcttt tagtgtttat tattgcttta
     7021 gtatttgcac catttattgt tagggtcttt gtaagtccag ataacacagt atttaaacta
     7081 gccttacaag gattaaaaat atttgcattt gcttttttgt ttgttggtat aaatatattt
     7141 gcatcaggat tttttacagc atttcacaat ggaaaaattt cagctattat atcttttagt
     7201 cgtgcctttg tttttataat cataggaatc ataattcttc ctcctatgtt aaacatgact
     7261 ggattatggc ttacagttcc atttgctgag gttataacca tatttatatc tattctattt
     7321 ataaaaaaat ataaatgtag atataagtat taaaaattaa tacttaaaat caacatttat
     7381 taaaactaat aaacctgctt taaaatacaa atttacaaat ttgattttta agcaggtttt
     7441 attttagtta taataagtca tttgcatact ctttaattgg tgcttttcta agtaataaaa
     7501 ttataaatat tatgcaaata actataattc ctacctttgt tccaaataaa ataaaaggat
     7561 tctgaaatga ataaataatt ttttctaaat acagtagcat tttatgcata tttttagttg
     7621 caaaattaac tatataaatt accattaata tcggtaatcc tatcaatata gtaatactag
     7681 taacttttct aactctatat gtaaaagctc caagtaacac tcctataaaa cctatacata
     7741 tttcatttat acatatttgt acaaaataat ttaaataagt tagtggcata cttgatgttg
     7801 aaggatctat cagtgctgat atagatgtcc aaatcatatc tctctttagt aaaactgata
     7861 gttctatact gtaacctgtt ataatttcta taaataactt cgataaaaaa atcaaaacta
     7921 tacctaaaat agaaatcaca aagcttaaaa taattaaatc tatgacaata gcttttatac
     7981 aactttttct atctgctctt atacttaaag ctcctgaaaa gtctttattt gctatattta
     8041 ctccatacac aaatagcagt atagttatat atgttaaaat aggattcaca atcgtggata
     8101 aattagtttt agatgcttct ccaaaaatct tgagaataaa cactggcaaa atattcataa
     8161 caattcccac aatcataaat ataattatat acaatttagt atttttatta aaaaatttta
     8221 tatatggctt taattcattc aattacaatt cctccttctt agtcatgtta acaaacatat
     8281 cttgtagccc tatgtatcct acatcaatat ttgaattttt aagtattttt tcatcacttt
     8341 cactaaaatc accatagtaa aaataagcaa ctgcatttcc aaatgccttt ttaggtttta
     8401 tattttttat acattctaat ttttctaact cttctttatt tccagtaata taatgagctt
     8461 tttgttttat gacatcaatt tcttcatcta taataatttt tccctcattt aatattatta
     8521 catgctccag taaatcatct atttcatcaa tcaaatgagt tgatattatt attgtccttg
     8581 gattttttat ataactatct aaaattatgt tataaaactc ttgtctattt actgcatcca
     8641 aaccaattgt tggctcatca aatatggtga tagctgaatt agaacaaata cctattatat
     8701 ttgaaagtat agttttcata cctcttgaca gttgtttata ctttttttta gtatttaaat
     8761 caaaatattt gcataattct ttttctaagc ctttatcata acttttataa aaactagaag
     8821 aaaattcaaa tatctgacct actttaaaat ctggactata aaattctttt tccctgacaa
     8881 tacaaacttc ttccaaaact tttatatctt cttttgggtt ctttcctaat atttctatct
     8941 caccttcatt ttgaattaac tgatttacca ttatatttaa taatgttgtt tttccagctc
     9001 cattcttacc taataaacca tatatcttat ttttttcaaa gcttagagac atattattaa
     9061 aaatattttg cttcttaaaa ctgtgagata aattttctat cttaatagaa ctactcatat
     9121 attaatcctc cttgaaatta attataatat caaccaattc ttctctattt atttctaatt
     9181 tgttagcttc ttgaagtagg ttttttacaa aattatgttt aaaattttct tttctagctt
     9241 cttttataat agtttttgca ccatctgata caaacatccc tatccccctc ttcttatata
     9301 aaatattttt atcaaccaat atatttatac cttttaatac tgtagctgga ttaattttat
     9361 aaagctttga aagctctgtt gttgatggaa cctgttcttc ttcttttatt ccatttgata
     9421 gtatctcatc ttcaattgct cgtgctatct gaataaatat aggttcttca ttatttaata
     9481 ctaatttcat aggttcctcc tttctccatc agttagttac tcaactaatt aactatataa
     9541 cttataatat cttgaaaaat attttctgtc aatactaaat aaaaaacaga gggaaaattc
     9601 cctctgtttt ttgttcttta tatttataat taaattttaa tttttgtaat cctatcccat
     9661 aagttaaaaa ctttaataat ctgttgtatc ttcatttttt aatattttac atattgagct
     9721 agttcctaac ctttctgctc ctgcctctat aaatttttct gcatcagaaa ttgatttaac
     9781 tccccctgca gcttttattt ttacattttt tccaacatgc tctttcataa gctttatatc
     9841 ttctaaagta gctccacctg ttcccattcc agtagatgtt tttataaaat ctgaacctga
     9901 cattgttact atttcacaca tttttatttt ttcatcttca tctaaataac atgtctctat
     9961 aatgactttt aatactttat cttctatagc tttttttatt tcttttattt cttttcctat
    10021 attatcataa tctttatttt ttatatctga aatgtttaca accatatcaa cttcatctgc
    10081 tccattttca atagcatctt ttgcttcaaa tacttttgta gcagtagttt gatatcccaa
    10141 agggaaccct atcactgtac atatctttat tttacctttt agatattctg atgctctttt
    10201 cacatatgat ggtggtatgc aaactgatgc tacactcata tctacagctt catcacataa
    10261 aattttaata tcttcccatg tagttgtagc ttttaaaata gtatggtcta ctgtttttaa
    10321 tatatgtttc ataaaatcct cctaaattta taattaatat aattagatta cttttttaaa
    10381 tgcaattttc tctttgcaat attcagtatc atatcaacct cttcaacttt aaaaatagtc
    10441 attagtagtg tataaattcc acctccaact ataactgaaa tagctagtga tacaaactca
    10501 ttaaatgttc ctactcccaa aattccaaat ataaatttat acgtaaagta tgataaaaca
    10561 cccataatta aagatgcaac taccgatttc aaagttgctt ttattatttt atcttgtcca
    10621 aaatatccaa cttttctctt taggttcaag aagagtaaca atatacatgc aattgatgat
    10681 gaactagttg caagagcaag accaccatga gccattggtt ttattaaaac taagtccaat
    10741 actatattta cccctacaga tataatccca tttaccatag gtgtttttgt gtcttgtaat
    10801 gaataaaaaa cctttcccaa aatatctctt aagccaaatg cagtcatacc aactgcataa
    10861 aaaattaagg cagttgctgt catttgggtt gccctcgcat caaaagcacc tctctcaaaa
    10921 atgattctaa caacaggagt tgcaaaaaaa atagaagcaa ctgaaatagg aatcatagaa
    10981 attattatca tatttatact agatttaact gaactagtaa acttcttttg attattttct
    11041 gcacttaact tagataacat aggatacata acagatacta ttgaagctgt aaatgtccct
    11101 gtaacaaaac catttaatct atctgcataa gtaagtgctg gaatgcttcc tttaactaat
    11161 gttgaggcta aagttgtatc taccaatgag ttcacttgat taacagcaac acctataaat
    11221 actggtgaaa gtaatgctag taatttaata aggctatcat ctttaaagtt taagtagtat
    11281 aagtatttgt agttcgtttt tttaacaaaa aacatgtaaa agagcagttg aactaccata
    11341 gcaaccacag caccaattgg aagtatgtat ggtccaaata tggtacttaa cattattgaa
    11401 ataattatta ctatattata gggtatactt ccaaatccaa ctacaataaa gttctcttta
    11461 atttgtaaaa atgctgacat aacacttgta atacctatga atattattcc tgttctgaac
    11521 ctcccatgac taaagtcaca gggttcctgc ttc
//
LOCUS       DAEOTL010000110        11308 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.111, whole genome shotgun sequence.
ACCESSION   DAEOTL010000110 DAEOTL010000000
VERSION     DAEOTL010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11308
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.111"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1582)
                     /locus_tag="KRH82_003448"
     CDS             complement(<1..1582)
                     /locus_tag="KRH82_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein CwpV"
                     /protein_id="HBG8656704.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSGGSSGGSSSSKVGQIKF"
     gene            complement(2580..3719)
                     /locus_tag="KRH82_003449"
     CDS             complement(2580..3719)
                     /locus_tag="KRH82_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBG8656705.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEGIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(4256..5095)
                     /locus_tag="KRH82_003450"
     CDS             complement(4256..5095)
                     /locus_tag="KRH82_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBG8656706.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKDELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(5119..5877)
                     /locus_tag="KRH82_003451"
     CDS             complement(5119..5877)
                     /locus_tag="KRH82_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBG8656707.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIAPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(5924..6397)
                     /locus_tag="KRH82_003452"
     CDS             complement(5924..6397)
                     /locus_tag="KRH82_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656708.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIIIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(6426..6842)
                     /locus_tag="KRH82_003453"
     CDS             complement(6426..6842)
                     /locus_tag="KRH82_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBG8656709.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(6889..7941)
                     /locus_tag="KRH82_003454"
     CDS             complement(6889..7941)
                     /locus_tag="KRH82_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBG8656710.1"
                     /translation="MKSVRFYGIRDLRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKVIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGIWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            8337..9017
                     /locus_tag="KRH82_003455"
     CDS             8337..9017
                     /locus_tag="KRH82_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBG8656711.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9150..9470)
                     /gene="sugE"
                     /locus_tag="KRH82_003456"
     CDS             complement(9150..9470)
                     /gene="sugE"
                     /locus_tag="KRH82_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBG8656712.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            9852..10679
                     /locus_tag="KRH82_003457"
     CDS             9852..10679
                     /locus_tag="KRH82_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBG8656713.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
BASE COUNT         3745 a         1951 c         1245 g         4367 t
ORIGIN      
        1 taaattttat ttgacctacc tttgatgaag aacttcctcc actacttcct cctgaagaac
       61 ctccacttga tgaacttcct cctgatgaat tagaacttgg actatttcca cttattgttg
      121 gagaattatc tcccttaaca ctacttattg tacctttatt atctatagta gtccctttag
      181 aattatttgt aactgtagtt atcttaccac cattagtcac ttttacttga cttgctccag
      241 atgctactgt taaactacca atctcacctt tagaattatt ttctatcttg gctccatttt
      301 tatcattaac ctttaagtta gttatttttc cgtagttaac aaaagttcca tcttttacat
      361 catctataac tacatcatcc acttttgcat agttatttac atcaccatta ggcatgttga
      421 tagtcacagt ctttgtatat gtaccattta agtttactgt tactgcttta tcagtttgta
      481 ttgtaaatgc ttctttaacc tcactagttg gcttaaagtt tataacatca ttagcagtag
      541 ctttatctat agctgatttt aattcagaaa ttgttttagc ttcaactgtt tttacttctt
      601 gtaatgactt catttcatta aatgctgtct cattaccatt cccaccaact ttagttatct
      661 tatcaaaact cttagagtta actagagatt tttgtgaagc tgataagttc tttccaacta
      721 aaactactgg tgattgattt ttagcaccta atacacctac tgctagtgca tctataagtt
      781 ggtcttgttt attcatacca tctttagtta cataagcatt ttttaaatct gtctttttat
      841 aaaattcttt tattactttt gcatttgtat catttctatc tgttccacct agtcttgtac
      901 tatttggtag tttattttta acagcttcag aaattgaact ctctccacct actacataag
      961 attgagttat tccagcatct tttataaatt tgtctgcaac tgctgttcca tttttagaat
     1021 cagcaagtat tactggcata ttgttttgtg cagctggtgc tcctacactt acagcatctg
     1081 caagtccttt ttcaccatta actacagcta ttttcttaac atcacttata gcatctaatt
     1141 tctttgctaa ttctaaggat gtttgatatc tctcagctcc agagattctc tcaaaagata
     1201 tttttaaatc ttttatttct ttttctatat ttgtacttaa tacagaagtt ccacctatta
     1261 agtatacttt tttagctttt aatctttgta tttctgcttt cgtcttatca tttaatttat
     1321 ctttacttgt taaaagtatt ggagcatttt ttgcttttgc aaatggtgtt gcagatagag
     1381 catctgctat agatgagtcg tttacgatta ctacctcatc agcatttttc catccatctt
     1441 gacttatttt aacagcagtt tcatatcttt cttgccctgt taaatttgtt gccacagttt
     1501 gtgcactagc tatgcctgct gttgaacttc cagctatcat tgtaactgta agcattgcag
     1561 caatcttctt tggtattttc attttatttt cttccccctt gtccatttga tattacttaa
     1621 ttttttaact ttgttcccgt tctaattcta aaggatactt aatatctaat tttaaagagg
     1681 tttctaacta taatgatttc ataattaatt tgtaattatt ttgttacatt gcagtcatta
     1741 tgtaaggaat aaagaaattt tcttattgat tgaaaaattt gtaaatttat attttaaggt
     1801 aagtttgatt tttatgttaa tgaattgtta taaaaaatag ggttttgtat aaaaaaagta
     1861 gcctttagaa ttaaaagcgc tactcttttt acaaataaat tttattattt atacttgtaa
     1921 ttatatatta aataaccaat tttatccata tgaaaaacaa ataattgcga tattttttta
     1981 attattcttt atatttacat tttaattcga attactttta taaagattat atctgttgca
     2041 tatactactt taagtgctaa tatatctccc cctcaattag aatcctcgtt atctcaatag
     2101 acgttttcta ctgtcaaagt taccaacatt tgaaacttat taaattttta tataaaaaag
     2161 acctagaata taaattccaa gtcatttttt attaaattta ttttttacaa tataatattg
     2221 tcatgattaa agaacacaaa tcatacacaa attggtcata aatcttacat aaatcatcta
     2281 caaaaaatac attatttata ttaaatctat ataactaaat taagagcata ttgtacaata
     2341 tgctcttaga aaagatattt cttgtttata gtttatagta tttctctatg atttttattt
     2401 ttatcatttc aaaaataaaa attaagatta cagttattat catattttgt gtactatttt
     2461 ctataatatt ataatgaaac aatgaaaaaa caataattaa tgaaattacg tttatagccc
     2521 cagaaatcaa aaatgccttt ttcttattat ttatatattc cctctccaga ttatctaaat
     2581 tagtctatat caagcatttt taagtactta tcattaactt tatatatatt tttttcttta
     2641 gacaaaatct ctatcccttc aagattatta aacacttcca tcaactggtc aactaattca
     2701 atttccttta ttccagcctt taagtatcta cttttattct tttttatata attttctaat
     2761 gtcatagaat agttatcttt attgcaaata tattttaata tatgttcttc tgttgctgat
     2821 agagttatgt cattttcaaa caattcttct tttaatatac tttctaaaga ttttctatca
     2881 tgcatattac gcatctcatt aatagattgt attatagact tgagcataaa ctctataaat
     2941 acagttaaat tatttccttt gttttctaca tcaagtatag ccttataata cttagttctg
     3001 tttttagata tcatatatga tattgaaaac tccttgaaag tatcatatcc tttatcaatc
     3061 aaatatagat atgataaggc tcttgatgtt cttccattac catcactaaa aggatgaaca
     3121 tatacaaagt aaaaatgaat tatagcactt ttaattaaat tacttacttt gctattttcc
     3181 ataaaatcta ttaatttact cataaagtca tatatcttca aaggttcaag ccctatatgt
     3241 ataatctcac cttttgaatc acatacatat actttttcag ttctatactc atattcttct
     3301 gaatccaagc agttttcgcc caatatatga tgcaaatcat atataaattt gtgactatat
     3361 aatttatcta agttgtctaa tccatattct aaggctctat gattattgta aatcatatat
     3421 tcacttttat tactaggttt catctttcct ctaattatag attttgcaat ctttctattt
     3481 gaaaaagcac cttctattac actagaataa taagactcta gtgccaaatc atttttatct
     3541 tctattattt taaatatctt acttgatgtt aatttatcta tttcatttat taaatttaat
     3601 atattttcag tttcatgata gtatagttct ttattatcaa aactatttat agaaagtacg
     3661 attttatttc cagtaaagta tttgtttttg tattcttcta ttgtcagttt aatcaccacc
     3721 ttagattatc tttatctatt aatattaaca aaaagtatta atttttacac tatttttgat
     3781 tatttgtttt ataattatca aactcaattt agcgttaaag cataataaat tttaataaat
     3841 aatgcaaaaa tttaagaata agcatttaaa atatatggca caggaagttt acaactatta
     3901 tttataatac attagttaca tattataata tctcgacaat gtcttaacaa tatctcgatt
     3961 atatatttta atatgtaact aatatgttat aatattttaa ttaaattaaa taaatttata
     4021 tttttttgaa attacttaat attttatata aaaatgaaaa agcacctcat tctgattaaa
     4081 aatctttctg agatactttt taaaatatta aatactacat atagcttaca taagtttaaa
     4141 atttaatcta ttataaaatt accctaattg ccaaactttt taatataaat tttccaacat
     4201 cctacaaata taatcaatag atatagaatc ctaacttaca ccaatatata tttatttaaa
     4261 atagtcctaa aatacctgta atagctccca ctactatcag tataaacatt atttttattg
     4321 gagaaagacc tttttttaaa gcaaagagta ctaataaagt aagtaccaaa ggaattaatc
     4381 ctggaaatat cttatcaagt aaatccgttt gaagactaaa tttaaaatca ccactagtat
     4441 aacttattgg tgtagataaa ttaataaacc tacctacaag tccccccatg actaaggtac
     4501 ctagtataga agccccttct ataaccttat ttactattcc accttgaagt atactttcaa
     4561 cagctttttt cccatactta tatccatttg tccacattcc aaaagaaatt gaagtcatta
     4621 ttatatattg agctattaca aataatatag gtcctgcaat tgatgctcct ccctcagtta
     4681 aaccaataca aacagccaac actataggag ttataactcc ttgagttaaa gtatcgccaa
     4741 ttcctgctag tggacccatc aagcctgttt tgatagcatt cataccatct ccacttattt
     4801 catctgctcc attagctttt tcttcttcca tagctattgt tattccatgt ataacacatc
     4861 cacatatagg ttctgtgtta aaaaatgcta gatgagtctc cacttcttgt tttaactcat
     4921 ccttatctgg atataatttt ttaagtactg gcaacattga atgtgaaaaa gctgttgatt
     4981 gcaatctttc ataattgtaa ttagattgtg caaagaaaaa ccatcttaac catgatttta
     5041 ttacatcttt cttgcttaac gttttcttag atacttcatt ttttatatct gacataatat
     5101 tttccccctc acatgtattt aagatgtagc actatctttt ccgtacttaa ttgaagtaat
     5161 tgtaagagca agtattactc caataacaga tattactatt atatctactt taaaataaac
     5221 agccattagt attcctaata tgaaaaaagg catagtaaac ttgtttccaa tcaattttaa
     5281 attcatagca atcccaagtg ctggcaacat agccccaatt acattaaata catgtaacac
     5341 attatcattc attacttcca acataccatc tatcgcattt ggaccaaaat aaacaactaa
     5401 taatgctggt ataaaactca ttgcaaataa cagtatctgt ggtggtgcta tatttataaa
     5461 tgctactcta tcaacattcc ctttttgaac ctctctatca gcccaatgtg caaaaaaaga
     5521 atttactgtc atctttccaa tccaaagtac agttgcaaca gttcccaatg gtacagctat
     5581 tgccattgca gtacttacat ctagcttaga tgctatagct aaagcagtac ctacatatcc
     5641 tgcaaaagct gggtccccca tctgagctcc ccctgctgat ataaagccta gatatatcat
     5701 atttatacct gctcctataa ttgctccttg aacagggtct cctaatataa ttcccgttac
     5761 aaatccagcc aatagaggtc tattccatgt aaaaaatcca acataagtca accacggact
     5821 ccaagaaaga taataaaaaa ttgctattaa tactgcttga attagtgaaa tgtgcatatt
     5881 cttcctccct attttctttt aaagatttac aagatagtct tctttataat aatgttccta
     5941 catcaatttt ctttgcatct ggtactattt gtataaagca tttaacatct tttgatatta
     6001 gctctctaaa tatttctttt tcttcatctg acacagatat atttttataa aaactttttc
     6061 taccaagccc tgctcccata cctccaacat tcaattcctt taaatctacc ccgctattta
     6121 ctaaacctaa gacagtttta gggtatttga ccaatactat taaattttca tctccattat
     6181 gtgattttaa gacttcagca cctgattcta catcatgtac ttcaacctta acagttgatg
     6241 gagctgccat ttgtaaaact tgaactataa atgggtcctt tactactaaa tcatccacga
     6301 ttattatcct ttttgctgat gtaatcttac accaagcagt aataacttgc ccatgtatta
     6361 atctatcatc aattcttgtt aatgctatat tactcataat tattcctcca gatttttaat
     6421 ttattttaca actttaaaac agttttaaca tctttgattc ctgatatccc aacttcctca
     6481 cataaattct tcaagtcttt taacttcata gtatctctgt ttaaaaataa ctctaaaagc
     6541 ataggtaaat ttacacctgt caaacattct aactcacata ccttagcaaa tttatttatt
     6601 ataatagcag atgtattaaa tggagttccg ccataaaaat caagcaatac taaaacccct
     6661 tcatccttat atttctcaat tccatcttct aactttctac taaactcatc tatgctgtca
     6721 ccatggttta atcctaaagt ttctacattt tcctgtttgc ctactattaa ttcagcactt
     6781 tctaacattg ctttagccat atttccatgt gtggctataa ttattcctgc catatgaatc
     6841 atacctttct taaccttttt tatatggatt attatttagt actctaatct aattatctat
     6901 attaatcatt atcttaccaa agaaaatatc ccttttgtat actttttcaa aataagctgg
     6961 tacttcttct aaatttattc tatgtgttac taatttttca acattcatat cacccttttg
     7021 catatgatac aatccagcac tccattcttt tcctgggaat ggaaaggagt ttccaaacca
     7081 aattcccttt acagttaatt cacttcttac tatcttttca aattgctctc tagtcaaagc
     7141 tacatcccca tatggtacac ctgcatacaa tactgtacct ccctttttag ctagcaacag
     7201 tacttgacca catgtcagtg gagtaccagc cgattcaata acaatatctg ctccatctcc
     7261 atcagttaac ctttttattt cttctacaat attcttttct tttgcattta tacaaatatc
     7321 tgcccctaac tcttttgcca agtctaactt ctcatcaaat acatccacag ctattacttt
     7381 tgtagaacca aatatttttg cccattgtat tgaaaataat cctattggac ctgtaccaag
     7441 tactacaaca gtatctccaa ctttagcttc tgacctaaaa agaccatgtc ctgctataca
     7501 tactggttct agtgcagcgg cagtctcata acttatctca tctggtattt ttattaaatt
     7561 tctctctttc acctttgtat actctgcaaa acaacctcca agttctttat ttcctattat
     7621 tgctacatta ttacatcttg aatacaagcc ttttttacat tcatcacatt caaaacatgg
     7681 catagctgga caaacagcaa ctctatctcc tattttaaaa ctccttactt ctttaccaac
     7741 ctgtgccact tctccagaaa attcatgccc taaaatttct ccaaccatat gtggacctgt
     7801 ctttgaatat tttgatatat cagaaccaca tattccagct acttttactt taattattac
     7861 atcatctttt tctaatattt ttggtacatc cacatcctcc actcttaagt ctcttatacc
     7921 atagaatcta actgacttca ctattaacca cccctacttt ttatttgaga atatattcct
     7981 attgtttata tgttaaatat ctaaagcaac tttcatgcca atatatgtaa gcattgtatt
     8041 catgcatttt acaaaattat cattaaatgt gtgtcaaagt gtgtcaaaag tttcttatat
     8101 taaaacttat gtgtgtcaat ataaacgaca ctaacatttt atattagttc tcttattata
     8161 agttttataa aatgtacttt ttttgttatt tttataaaat tgttcggaaa tttcccttct
     8221 atttgtgata taatattaaa tataaggtat caatataaat tttcatgcga atatcagaac
     8281 ttttttgaca ctaatgcctt attcaatata ataatttaac tttttggagg ttgtttatga
     8341 aaaaagtgta tcaaggaaag actaaagatg tttttgaatt agataatgga aattacttac
     8401 ttaaatttaa agacgatgta actggtaaag atggagtatt tgacccaggc gaaaatagtg
     8461 taggtctaag tatagatgga attggtagag ctaatttaga gacatctgtt aagttctttg
     8521 aaattctaaa caatgctgga attaaaactc attatgtaag tgctaattta gaagaagcaa
     8581 ctatggaagt tctaccagca aaagtttttg gtaatggatt agaagttatt tgtcgttata
     8641 gagctgtagg tagtttctta cgtcgttatg gttcatgtgt tgaagaaggt gctaaactag
     8701 attgttatgt agaagcaact ttaaaagatg atgaccgttg tgaccctctt ataacatctg
     8761 aaggtttaga agctttaaac attatgactc aagctcaatt tgattcaatg aaaagcatga
     8821 ctcaaaaaat ttctaacata gttcgtgata ctatagctga aaaaggtctt gagctttatg
     8881 atattaaatt tgaatttgga ttctacaatg atgaagtaat cttaatagat gaaatagcat
     8941 ctggaaatat gcgtgtctat aaagatggtg taatagttga ccctatggat ttaactgctc
     9001 ttttattaga taaatagtat atacatataa tttacaaata taataaactt ataaataaga
     9061 taagctatga agtaaagact ttttaaatgt tgattatttt taaacatttt ctcgccttta
     9121 atttcatagc ttatttaaat taatatactc taattagtag ataatagctt taaccctaca
     9181 attcccacca caataaaacc tatacatgca attcttgata tactaatagg ctcatttaaa
     9241 atagccatgc ctacaatagc tgtaccgacg gtaccaattc cagtccatat tgcatatgaa
     9301 gttccaagtg gaagatgttt tagtgctaat gacaaaaaat aaaaacttac aatcattcca
     9361 acaacagtaa gtatacttgg agttaattta gaaaatccat gtgaattttt tagttgaaaa
     9421 gcccaaaaca cttcaaacaa acctgcaaca aacaaaaata accatttcat aaattcatcc
     9481 ctcttttcaa atatgtctct tatttttcca ataaaataac ctgagaaata ttataaaata
     9541 tctcccaggt ttttgtcctt ccgtgttcac aacaaaaact atgttgtggg ttttatctcg
     9601 gaccagacca atcattaata attgcggaac cctataaaac tctattaatt attctatttt
     9661 atctataata atactatcaa catatataaa aaaagtcaat atatgggttc catctataat
     9721 aaaaataact tttatatacc ttttaatatt cttattcact tctctccata cccatttagg
     9781 tcaatctaag aatatctaat ttttatttaa tatgttataa taacataaaa atattgaaag
     9841 gagtaatttc tatgaatttc tataaaattg cagtatgtca gatgattact acagaaaata
     9901 aaattgaaaa tatcaatcat gctgtagata tggtaacaga agctgccatc aatggagcta
     9961 aaattgtagt tttgccagaa atgtttaact gcccatatga aaataaatat tttcctaaat
    10021 ttgctgaaga atatccaggt gaaacaacaa cgatattaag taaattagct gagaaacatg
    10081 gaatttatct agtttctggt agtattcctg agttagaaga tggaaaaatc tataatactt
    10141 gctatgtatt tgataaaaat ggagctctaa ttggaaaaca tcgtaaaatg cacttatttg
    10201 acattgaagt tacaggaaaa gttagtttta aagaatcaga tactcttaca gctggaaatg
    10261 atgtcactgt aatagatacc gaatatggaa aagttggtat agctatttgc tatgatattc
    10321 gtttccctga gttatcacgt ttaatggctc ttaaaggtgc tgaaatcgtt atcttacctg
    10381 ctgcatttaa tatgactact ggtcccgccc attgggagtt atctataaga atgcgtgctt
    10441 tagataatca gatattctat gttggtgctg cacctgctag aaatatgaat gcttcttata
    10501 tagcttttgg aaattcaaga atttcagacc cttggggaag aataattgct caagctgatg
    10561 aaaaagaatg tattatttat gctgacattg atagagattt aattcctgac ataagacaac
    10621 agttaccact tcttaagcac agaagaactg atttatatga acttaatact ttgaaataaa
    10681 acagaacata accccataaa tcgtaaatta agtgttaaaa aaatttatgg ggttctcatt
    10741 aatttgattt aaaattaatt tcataaaaat aatgctaaaa ttaatttaat taaataatac
    10801 taataattac taatgattat gctaattatc agcatttact aatttaatca ctattagtta
    10861 tttcttttat taaatatctt tactttttta cttattatgt cttctagctt tacatttgga
    10921 ttatggtatt tctttctatt tttagtcaca tctttctatt gaattacttg cttaaaacac
    10981 caatgcacac atgccagata atgttcacaa ttatgtagaa atcttgctct accttcttca
    11041 atgttgatat tatctctcct agttgatatt atctttccta aaatttcttt taattaaaaa
    11101 acaacattag ttgatatatc aagtatattt taagcaactg aaaaaaacaa taataattga
    11161 tatatcaact aattaatgta gattaattca tttttataat ttatatactt tttaattaat
    11221 ctaccttatt taattaaaat ccttcctttc tatttatcca ttttcaactt aaattataag
    11281 atttcatcag ctatattttt gcatacca
//
LOCUS       DAEOTL010000111        11135 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEOTL010000111 DAEOTL010000000
VERSION     DAEOTL010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11135
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.113"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..599)
                     /locus_tag="KRH82_003458"
     CDS             complement(<1..599)
                     /locus_tag="KRH82_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBG8656714.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIK"
     gene            complement(671..1024)
                     /locus_tag="KRH82_003459"
     CDS             complement(671..1024)
                     /locus_tag="KRH82_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBG8656715.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1102..1305)
                     /locus_tag="KRH82_003460"
     CDS             complement(1102..1305)
                     /locus_tag="KRH82_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBG8656716.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            1434..1643
                     /locus_tag="KRH82_003461"
     CDS             1434..1643
                     /locus_tag="KRH82_003461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656717.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLPIKNHNSLWAFIDK"
     gene            complement(1695..1925)
                     /locus_tag="KRH82_003462"
     CDS             complement(1695..1925)
                     /locus_tag="KRH82_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656718.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(1927..2334)
                     /locus_tag="KRH82_003463"
     CDS             complement(1927..2334)
                     /locus_tag="KRH82_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656719.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(2694..3143)
                     /locus_tag="KRH82_003464"
     CDS             complement(2694..3143)
                     /locus_tag="KRH82_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656720.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AIKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            complement(3157..4083)
                     /locus_tag="KRH82_003465"
     CDS             complement(3157..4083)
                     /locus_tag="KRH82_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656721.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESNLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4208..4990)
                     /locus_tag="KRH82_003466"
     CDS             complement(4208..4990)
                     /locus_tag="KRH82_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBG8656722.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5146..5766)
                     /locus_tag="KRH82_003467"
     CDS             complement(5146..5766)
                     /locus_tag="KRH82_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBG8656723.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5854..6417)
                     /locus_tag="KRH82_003468"
                     /pseudo
     CDS             complement(5854..6417)
                     /locus_tag="KRH82_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729092.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            6653..7468
                     /locus_tag="KRH82_003469"
     CDS             6653..7468
                     /locus_tag="KRH82_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBG8656724.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIGNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMESDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDHQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNAKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PYIFMHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSARAEMERL"
     gene            8140..8907
                     /locus_tag="KRH82_003470"
     CDS             8140..8907
                     /locus_tag="KRH82_003470"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBG8656725.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9235..9912)
                     /locus_tag="KRH82_003471"
     CDS             complement(9235..9912)
                     /locus_tag="KRH82_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656726.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10062..10379)
                     /locus_tag="KRH82_003472"
     CDS             complement(10062..10379)
                     /locus_tag="KRH82_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656727.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10401..10739)
                     /locus_tag="KRH82_003473"
     CDS             complement(10401..10739)
                     /locus_tag="KRH82_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656728.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3703 a         1740 c         1577 g         4115 t
ORIGIN      
        1 tgcttaatgt ttgattgaat ttttttatat ggccaatccc accatttaat ttctaataat
       61 tttgaaattg tatcattatt aaatctcttt tttataattt ttgcaggtac tcctccaaca
      121 atagaatacg gtgggacgtc attagtaact actgctcttg ttccaataat tgcaccatca
      181 ccaatattta cacctgacat aattatagaa tcataaccta tccacacatc atttccaatt
      241 ataatgttac ccttattgtc ccaagcgtcc gttatatggt tgatatcgag tttccattct
      301 tcataaaaga tgggaaaagt atatgtggat tttgatttca ttgagtgatt tccactagtc
      361 attagaaatt ttgcattaca tgctattgag caaaacttac caattattaa tttatcattg
      421 tttatagggt aatgatacaa tacattgttt ttctcaaaat ctcttgggtc attataaaag
      481 tcattatata ttgtgtaatc tccaacttct atattttccc ttgttattac atttttaaga
      541 tatacagttt gataatcatt acttcttgga tataccttat ttgaacttgg aatagtcata
      601 tttaaatctc tcctttaata tatattatgt ttttgactat tccactacta caatacatct
      661 cttcacagaa tcactccttg ttaagaatct tcataagata atggcgtcct tttttagtgt
      721 taagtcggat attctttctt agtacattct ttttagcgta taactgacaa actgtcattt
      781 tcttaccaat agtgtcaatg ctatcatcaa ggtcattttg tattgctttt tccttatccc
      841 ttaatgatat atcatcacgt tttccctttg ggggtttatc agtaggtaca agtttccaag
      901 agtaaacaaa ttgtggttta ccaaatgaat atacatactt atatgcgtat cttccatctt
      961 ttctctggct ctctccagtt cttaaaattc tatctttatt atctcgtctt ttttcagttg
     1021 acatgataag aagctcctct caataaccga attgagcttg atacgtcata tgaatattat
     1081 aacatataag gctcaatttc attagataac gtcaagtgta tcaacgattt tctcaaattg
     1141 ttttctcttt atttgaatgc gattgctatt cataatgacc cagccagaat caaggttttc
     1201 atcagcaagt ttacgtaatt ttttctctcc aatacgaaag tattttgacg cttcttcaat
     1261 cgtcaaggta tatttttccc aaataggtac atcagtattg ttcatagaat gtatcactcc
     1321 tttctatgtt cgtagttcag aagtagatag atggctttgg taagctccat tggtatttca
     1381 accaatccca ttcttatggg cagaaccgtg tcatacaggt gtatcattat actgtggtac
     1441 aggttacggc aaaacaaccg ttccaaaggt tattcacaaa tcactatata gtagctctct
     1501 tgattaaggt catggcgtat agtatttgtt ggctatctgt atcacaaacg tatctatcta
     1561 ctttattcag ttgtcaaaga acagtcggca ttgatttgcc tataaaaaat cacaatagct
     1621 tgtgggcttt tatagacaaa taattagtga ttctccatgt accaaatagc ttgatacatg
     1681 gagagagggc gagattaaga caaattaaat ctcaaaatag cagtgattag ttttgttcct
     1741 agcattcgct ttgtttcttc ttctacatga atatagggat ttccgtattc atcaaataaa
     1801 gttttctgtg aaagacgaat gatatagtgt tcaaaatgtt taagtattcc gtttattgca
     1861 tttacatcgc catgtacagc aagtaaaata attgtaaaag gtaatacttc tttagtaggt
     1921 ttcatttcaa tgttcctcca tgagttcttt caactctttt agtgcatttg ttttgtgata
     1981 atgtatggta ttttctgcta aatccatcaa tgttgctatg tcagcatttg tcatgttgag
     2041 aaagaatgaa agtagaatta tatcttgttt tctttttgta agttttccga ttgcttgtgc
     2101 cattaataca tcttcaattc gtatgttgta gtcgtaagaa accatacaga tgtagttaga
     2161 atcataatca tctaaaatac tcaatttact taattctgca agtgacaaag attcgagaga
     2221 taccaaataa tcatttctgc gtttattttc gtcataaata tctctagcat agttacgcaa
     2281 aactgtttta cagaaactgt cgaattgatg ttcaattgtc ttttcatcaa ccataagatt
     2341 tcaccctctt tccatcgcaa ggagttaaat aaccttgctt actcctatca cggtgggagg
     2401 gaattaaatc ttcgataaat ttcaaaaaaa agagaaaaaa atacacactc tgcctatagg
     2461 gcaaaaatgt gtattcttta aaacgtattt aatttatatt ggttgtaagc caccaccata
     2521 ttgatgtatg gaaatatgca ttggctagct tttcataaaa atacaaagat gcataagaaa
     2581 ttaatagagg ggaaaaactt attctgttat taaaaagtag gttaattcta ataaatgcta
     2641 ttgcggtcga attaaactat atacatggca atcaatcatg tttctattct ttattatgaa
     2701 ttgtgacagt attcttcaat cttaaaacca catttttcca atactttact tgaccctcta
     2761 ttgtaggaat atacattagc atgaattttg ttaaggttgt atttttcaaa ggcaattttg
     2821 catatttctt ttattgcatt tgttgctatc cctttgcccc aatagttcct agcaagccag
     2881 taacctaatt cagcattttt attaatagag gtatcttctt caaatgttag gctgatactt
     2941 ccaatagccc tttcttgata aaaaatagca tagctaagtt gtttaacatc tggagttgcc
     3001 aaacaaaaac taataaaatc tctagcgttt tgctccctat aagggtgggg gaagttgtca
     3061 cgaagattgt ttgcaatttc tttatcattc gcaaactcaa ctaactcggt aatataagca
     3121 taattccact ctataagttc catttttctt ctccttttat gaaacagcta caagaaatct
     3181 ttctaagcca ataccactta tcaaacagcg ttctttttta tttccaagca tttgataagt
     3241 ccagtcaaca aatccaccgt cagctatttc aacggtttca tttccttgtt tgaccgatat
     3301 tttgaaattg atacctttat aataattatt atcaacatca tcattatgaa ttgataactc
     3361 tatattagga aaaataagtt tgatagtttc aaccattctg tcgaaaaatc cgtcattatc
     3421 tttgtatccg tttcttttgc gtagaataat agagaaacga acattttcta tttcacttaa
     3481 tatatcttta taatagttta agtgcttttc taacaacatt ttttcacaag tgtaagaccc
     3541 tgtatctata ccagatgaaa ccatacaata taagccaaaa tgtgaatata aacctttacc
     3601 tacaaaattt tgtgctctta ttaccctagc agtagtagcc atgtggatag gtatggtatt
     3661 attttcttct tttcttttta atttatcagc aataattatt gccaacatat ttgaggggtc
     3721 tgcaagtgtt tctgtccctc gtagagcact tactacgtta tattgatcta cggagccaaa
     3781 aacgctacag ctacctaatg gggcagaggg agaaagcata atcgtcttga tatccatatt
     3841 gaatgctttt ctcaataaat ttgattccaa agcatgaatt tcttctggat ctataccgct
     3901 agggatagta aatctattta gttggtatga ctttagaata tcagttgcag ttaaagtatt
     3961 tgcttgtcta tcaaacactt ctaatagaag tgagttcaaa tctgattttg atagagctga
     4021 taacttatca actatattct tatccccaat tttatttgta attctactta aaatatcact
     4081 catagttatc ctccatactg ttactttcaa aataattata gaattgttac aacaactaat
     4141 ctaggtcatt tgaccaaaaa tgaaaaaaca ctgaatattt actattcaat atttttttac
     4201 tttgggttta tttgattaaa tcttgaaaat actgtaatgc aaccctttca gcttcaacct
     4261 ttcggacaat aggactttgt gataattcct ctcttaactc aagatacagg ttgatagtag
     4321 cctgcaatgc attaacacag cttttatatt catggttagc aaccgtcttt tctaatgctt
     4381 caatatattg gggtgcgtcc aattcaattt ttctaactcc acgaggtaat ttacctaaga
     4441 gaagttgtat taatggggca agtactgatt gtcttaaaaa agataaaaaa tcaattgttt
     4501 caaatagttc tctacgtcca atcttagtgc aagcgtaatg aacccaaatc caaaatctat
     4561 cttcaatcca ctgtaagtct ggagttggga agtatgcttc ttttttagaa taaatttctg
     4621 ttatgcagtt gttttcttca tagagaatag ctgaatcttc aaccctatct agtaaaccat
     4681 ctaaggttgt aaacttaaaa tcaacatgaa gaacagggga atcatagagg gaaattatca
     4741 atcgaggttc tccaacatgt tcgccagtaa aagcagaaac taatgttcca aactgttcca
     4801 caataagtaa tctctcttcg ataacttctt cataggattt atcatctgct acaatcagaa
     4861 aatccaaatc agaatattca tctaacgatt ttgtgatata agaaccgcta attgcaagtc
     4921 ctattatcct actatctctt tttgaaaatt ctaatacgtt ttgtatcatt ttctgttgtg
     4981 ttttagtcat aatataacac ctctcactgt cttttattag ctatcaatcc aacataatta
     5041 tgcataggag tattatataa tgaagaaata aaaaaaaata ggtcacttga cccgaaataa
     5101 aaaagcattg aataattatt attcaatact tttttgaaat tatacttatg ttgtaggaag
     5161 attctttaat acctctcgct gattaattac actaaatctt ttgttttcat aagcaattag
     5221 atgttcttgt acacattcat ttatagcacg attaatgctt ctaattggag cgtttacttc
     5281 gctagcaagc tgttttttgg taagcagatt taattcactt ctataatagt gtaaggatat
     5341 acacctcaga agtcgttctt taacacttaa agatgataat tcttcaatta attcagcatt
     5401 tacaactaat ttactagata tttctcgaat cagaaatttt gtagcttcaa aatctcccct
     5461 taaccagttt aaaaaatcat ctctatgaag tttatataca ttacaatctg tgaaagcgac
     5521 aatttcaacg ggttttttcc catcattaaa ttgttccatt tctccaaaaa aactaccact
     5581 tctataaaga tgaatcgttg agatgtttcc tttcacattt aagatgaatg cttctgcaat
     5641 accgtcaatc ataagaatta catattcatt ttcttgctca gcaaaaagaa tagtctcttt
     5701 ctttttatac gtttttttaa caagcttctt tttaatatct tcattcataa aatcaattaa
     5761 atgcatattc atccctcctt accaaatctt tgattaaatt atatcatctt tcaattagtt
     5821 aggtaagata gtaaaaatat atttacatag aaactattcc attattattt tccagttgtc
     5881 atttttctgc aaaaacttat cactgtcacg actggagata ccagtaagaa atgttaggat
     5941 atcaatcgct aaactttcag aatccttttt acggctcaaa atgacgtaat ggtcaagcaa
     6001 tcctttgttt tcatcatcac tggttaaatt gacaatgttt atctcatggg ctatttctgg
     6061 tagcgtttct ttccatttgc cgcgttttgc tttagggtca actatgaccg cctatccgcc
     6121 gaatagtacc gcatagtaaa caagcatatt gttactgaat aatttaccac cacccaatga
     6181 accgataaac gcagacgcta acgcattggt aatagaaccc tttacccctt gactagcaag
     6241 ggcaggtttt agatagacat tctttccagt gtccagattg tagctaacat agatatcctc
     6301 atgttcgcca agggtttgtg tcgctccaaa accaagtcca gccaaaaaat ccgaagtgac
     6361 atattgaata taatcattga tgtaacgttt gctgacagga ataaattcgc catgcaatcc
     6421 caacatatcc ccaaagggat gcacgagctt gattgataag tcgtcgtaaa agtctttgac
     6481 ttcatcacaa tgccttttta gctcgtcaag atcctttgta gatacacgga caacatagct
     6541 aagtttatac atagattctt tacagttaaa agtctgtttt taaaaaaatg tataaattat
     6601 aaatcaaaat atagatacta tcaatgaccc actaggtgca aaaagcattg atatggttaa
     6661 attatcagac gctaaaagct gggctatccg aatgagtgaa gatgggtgtg cttataaatc
     6721 cattggcaat tataagcgct cactgaaagc gtcgtttttc atggcaattc aagacgactg
     6781 tattagaaag aatccattta attttcagtt aagtgatgtt ttggaagata caacagaacc
     6841 aaaaatcgct ctaacaccag aacaggaaat gggcttatta tcctttatgg agagcgataa
     6901 gacttattgt aaatattatg atgatgttgt tatcctctta gaaacaggac tacgcatttc
     6961 tgaattatgc ggtttgactt tagaattgga tatgaaaaat aaagccatta tggtagacca
     7021 tcaattgttg agtgatacta agattggcta ttatgtagaa gttccaaaga ccacacaggg
     7081 taagcgagaa attccaatga ctgaaagagc ttatcaatca tttgaacgta tcgttgaacg
     7141 gcgtaagaac gctaaagcag aaccaatcat tgttgatggt taccagaact tcctatttct
     7201 taaacaagat ggattaccaa aacaagcaac tcattatcaa agcatgttaa gagcgttagt
     7261 caagaagtat aacaagaccc atgaggacaa gctaccaaag attacgccat atatctttat
     7321 gcatacactc tgtacaaata tggctaacaa aggaatgagt cctaatatat tgcaatatat
     7381 tatggggcat aaaaacatta ctatgacgct tggctattat gcacatggtt catttagttc
     7441 tgcgagagct gaaatggaac ggttataagc ctagtagtat gactagagtt tactacttat
     7501 ttactacttt tgatggcatt cttatacggt taaatgccaa cttatgcaaa gtatcttcca
     7561 aaaagaaaat gtcgatactc cttgtagata caggatatat cgacatttac caacttatga
     7621 aaagataatc aaatttaata taagtttttc aaataaaaag atactaaatt ctttttcgag
     7681 aatctatata acattactta agcttggttg gggtataaac aattgagtag ctacttttgt
     7741 atggtgttca actttagtca aaactcttaa ataatgcaaa tgatttagat tcattaatat
     7801 tcaatctctt cataagtagt gaaattcgag ttatttctgc ataattatac tatgatttat
     7861 agattaattc tattagcatc cagaataata ttgtttatat gaataaaatt taaagaatat
     7921 tatgaaaatt ataggatgtt aaaataaatt taggtaaaaa agaagtgttt gtatattata
     7981 gagtaccttt tctaaaatat gtgggattgt tttaagaatt agaataaaaa ttatttttaa
     8041 attagtattt ttataatgta tagtattttt aatgtataat taaattgtgc agaaaataga
     8101 atttaaagtc ctatagaatt tctgattatg gaggagaata tgaaaagaaa agttcaagta
     8161 aaaaatatta ctattggaga aggtagacct aaaatttgtg taccaattat tgggaaaaat
     8221 aaaaaagata ttataaaaga ggctaaagag ttaaaagatg catgtttgga tattatagag
     8281 tggcgagttg atttttttga gaatgtagaa aatattaaag aagttaagga agttctctat
     8341 gaattaagaa gttatataca tgatatccct ttattattca catttagaag tgtagtagaa
     8401 gggggagaaa aattaatatc aagagattat tatactactt tgaataaaga aatttctaat
     8461 acaggtttag tagatttaat agatgtagag ttatttatgg gagatgaggt catagatgaa
     8521 gtagttaatt ttgctcataa aaaagaagtg aaagtaatta tatctaatca tgattttaat
     8581 aaaactccaa aaaaagaaga gattgtatct cgtttatgta gaatgcagga attgggcgca
     8641 gatttaccca aaatagctgt tatgccgcaa aatgaaaaag atgtgttagt gctacttgaa
     8701 gctacaaatg aaatgtttaa aatttatgca gatagaccaa taataacaat gtcaatgtca
     8761 ggaatgggtg ttataagtag attgtgtggt gaaatatttg gttctgcatt gacttttgga
     8821 gctgcaaaaa gtgtttcagc accagggcaa atatcattta aagagttaaa ttcagtactt
     8881 aatctattac ataagagtat taattaaatt aattatatag aaatattaga cggtattttt
     8941 gaagatataa attaaatata aaaaactttt cagatagtaa aatttaaatt gggcaattat
     9001 atctgaaaag caactattta gtgtgtattt tgaaagtgat atagaaaatc ttataaatca
     9061 actatggcat atttaaaata tgccattaaa acctactaga cattagatta tagatggtat
     9121 actagcattt ctattattta tagatagtaa gttttcataa taactgtttt atctaaagta
     9181 gaagatatat ttgtattatg tatatttgtc attatttttt tgtaattatg tatattaatg
     9241 gttatatatg taatataata ttatcactct attttttgta tattgtacat tacaacattt
     9301 atatctatca tcatcaatta cagtagaatg tatgggatac ttattttcac ttaaccaata
     9361 tttttgcata ttctttgtcc aagactttgg aaacttcaat actttcttgt ttattataac
     9421 atcctcatct tcaaaaatat taacttctct ttctattttt atttttctgt tgtatatctt
     9481 attgatagat tctttgtcga gttttatgtc tctatacata tcagggcaat agcaacaaac
     9541 ataatttctt ttttttcgac gtttaaattt cacaactttc tctatgctaa tttctaattt
     9601 ttttgtacca tcttttataa atttaatatc ttctatgttc tcgcttgaaa aaatttctgt
     9661 caatcttaaa gtatctacag tttctctaat tatttgcttt ttataagaag agaatccata
     9721 tccaaaagaa aggtttaatt tattagggat gtagccattt ttatatttaa acatcttaat
     9781 tttttccaat tcagcattat ctttaaattt caacttttca tacctaaaag ttactttgct
     9841 aaaaagagta tattctacat caatatattc ttttgcaatc ttaaatttat cgctaccttc
     9901 aatcacaatc atagcctatc tccaatcgtt ttatattaaa ataaggccat agaacatggt
     9961 ctaatagtac tcattagcac tataagacaa tgttaacaca aaaagacaaa aaaaggttat
    10021 ttatttcaaa taaccttttt ttttatataa aatataaaga attatatttt attctttttt
    10081 atgatgtcta taatctgtga tatcagattt agttctcttg aatttaagtc ttttaactct
    10141 tcatttatat cattttctaa atatgttttt ccagtggaag taatatcttt tataagaaca
    10201 tctgcagaaa tatttaatat atttacaaat tttatgaatg ttttaagact tggattcttt
    10261 ttaccacttt cgatttgagt tatataccaa ggcgatactc caaccatatt tgcaaattct
    10321 tttgaagtta aatttgcttt tttccgttct tctttaagtc ttttacctat ataattcatt
    10381 attgttacta tttccctcac ttatatttct ttgtatttaa tgatgcactt tattaactct
    10441 agcattgcaa tttgttcttt ttcagttaat ttattaatca tttcataaca ttctaaaggt
    10501 acagagttat caacgccttc tgttgtaata atatttgcaa ataacaattc aagtggtatg
    10561 tctaaagcag tagcaatttt cattataata ttgatagatg tatttgtctc agctctttca
    10621 atctgaccaa tatatgttgg atgtaaacct gccttttctg ctagaaactc ttgactatat
    10681 cccaattttg ttctatagac ttttattcta tctcctatta tttttcctat atttgccaat
    10741 tattatccct ccactttaga ttatattcat agtttaagtt gttttatata gactatttat
    10801 acttttttag tctaaatata gactatatat gtttttatac tgaaataagt gctatttatt
    10861 tttgtatagt ctgtatctac aataaacaaa tatggataaa tcatattttt aattagagaa
    10921 atattttcat aatttcatag ccatactaca ataataaaac gaattaataa tatgttaatt
    10981 atagcatttt ttattgtaat tacatattag atatgtagaa tatattttga aaattaaaaa
    11041 aattttctat tttatatatt gaacaattta tgtaaataga aaatttttca ataagacttt
    11101 tgagtttaat cattatattg gtaaggtaaa cattt
//
LOCUS       DAEOTL010000112        11109 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEOTL010000112 DAEOTL010000000
VERSION     DAEOTL010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.114"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(93..1082)
                     /locus_tag="KRH82_003474"
     CDS             complement(93..1082)
                     /locus_tag="KRH82_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBG8656729.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLRMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLIVLCGNKDAQPVVNSSSIY"
     gene            1522..2277
                     /locus_tag="KRH82_003475"
     CDS             1522..2277
                     /locus_tag="KRH82_003475"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBG8656730.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(2708..4366)
                     /gene="bclA2"
                     /locus_tag="KRH82_003476"
     CDS             complement(2708..4366)
                     /gene="bclA2"
                     /locus_tag="KRH82_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBG8656731.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGVNGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFNSSFING
                     TNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAKAVNTLT
                     SSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(4724..5263)
                     /gene="hpt"
                     /locus_tag="KRH82_003477"
     CDS             complement(4724..5263)
                     /gene="hpt"
                     /locus_tag="KRH82_003477"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBG8656732.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(5591..6898)
                     /locus_tag="KRH82_003478"
     CDS             complement(5591..6898)
                     /locus_tag="KRH82_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBG8656733.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDVAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(7322..9097)
                     /locus_tag="KRH82_003479"
     CDS             complement(7322..9097)
                     /locus_tag="KRH82_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656734.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKVDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(9094..9231)
                     /locus_tag="KRH82_003480"
     CDS             complement(9094..9231)
                     /locus_tag="KRH82_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656735.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(9309..9878)
                     /locus_tag="KRH82_003481"
     CDS             complement(9309..9878)
                     /locus_tag="KRH82_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBG8656736.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(10062..10697)
                     /locus_tag="KRH82_003482"
     CDS             complement(10062..10697)
                     /locus_tag="KRH82_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBG8656737.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT         3389 a         2060 c         1283 g         4377 t
ORIGIN      
        1 taaagcgaac cattaatctt tctataattt aataaaatga actactaaat tttctatata
       61 tcaataaaat aaactattaa actttttata atttaataaa tagaactgct gtttactact
      121 ggttgtgcat ctttattgcc acaaagcaca attaacagat tacttaccat agctgcttta
      181 cgttcttcgt ccaaagtcac aacattattt tcacttaaat tagtcaatgc catctctacc
      241 atacttacag ccccctcaac aatcttttta cgtgctgcta ttatagcctc tgcttgttga
      301 cgttgtaaca ttgctgctgc aatctctggt gcataagaaa gatgagtaat tctcacttca
      361 cacacttcaa ttcctgcaat gtcaaccctt gattgtaatt catcttttaa tctatctgct
      421 atttcctgac tactaccacg aagagatttt tcatctccat cttcagatac atcatatgga
      481 taaagtcttg aaacattgcg aatagtagaa tcacactgaa tagataagaa tgtattataa
      541 ttatccacat taaatactgc ctttgttgca tctataacct tccaaattac aaccactcct
      601 attataattg gatttcccaa taaatcattg actttctgct tttcattatt aagagtcatt
      661 gtttttaaag atactttttt gccccttgaa ttagttgata tatctacctt ttcatcagat
      721 gaagatttcg atacattaat tcttgatact gctgggttta ttgctgaaca aaatggattc
      781 acccaatagt acccttcttt ttttatagtt ccataatagt taccaaacaa aactagaact
      841 atagcttctt taggattaat cattcttagc ccaaaaaata ggataaaatc tactactata
      901 aatacaagtc ccaaaattaa cataagtgaa cctattccag taaatccact atcaagtttt
      961 actatcccaa aaaccatgat acctattgaa actactaaaa ataataaaat cattatcaaa
     1021 gctgccactc cattgaatac ttttgcgtct ttctcttgat aagttttttc ttcttttaac
     1081 atatctatca ctcccatctc agtatattaa gttaagatat ctctaattta ataataacac
     1141 ttttaacaat taaattgttg aatttaaaat taatactata tgtttatata ttttttatac
     1201 atctttatgc atacatgtat ttagttattt taatgtatta atattgattt ccaaataaat
     1261 catatgatat atgaatatgg tatttcaaaa ttaacttttt agttcatggg gcactctttt
     1321 tggtatgaag tcaaatatat ttttatcatt taaacaatga aaaagaaatt tatctatatt
     1381 ttgaaaaatc cacttaaatt ttttaatgta agataaattg taagcttatt atcactaata
     1441 ttattttata taaattatat tagtgataaa ataaacttat agaaatataa caaattttta
     1501 ttaatttcat aggaggaatt tatgttgaaa gttataatta gtggctataa tggaacaatg
     1561 ggaagagttt tagcagaatg tgtaaaaaaa gataatgaat tagagttggt ttgtggtgta
     1621 gctaggtctg ctgatgaaaa aggtcatcat agtgatacaa agctttacaa aacaatgact
     1681 gatgtaactg aaaaaactga tgtcataata gacttttcac atcatgagac tttagagcca
     1741 atattgtcat atgctctaaa aaataataca cctgtagtat tagctactac tggatatgac
     1801 gaaaatgact taaataaaat agaagaagca tcaaaaaaca ttcctatatt attatcatca
     1861 aatacatctc ttggagtaaa tatattaata aaattagtta aggatgcttc aaagatgtta
     1921 gaaggttttg atattgaaat catagaaaaa catcacaata gaaaagaaga tgcccctagt
     1981 ggaactgcta ctatgatagc taatgcaatt agagaagtct tgcctgaaag tgaaaataca
     2041 catggtagat atggtagaga ttgtaaaaga aaaccaaatg aaattggaat acactctata
     2101 agaggtggca atataatcag cgaccatgat gttatatttg caggtgataa tgaagttctt
     2161 acattaagcc atcattctca atctgatgaa gtatttgcaa acggttctat agttgcagct
     2221 aaatttttaa ttggtaagca atctggactt tataaaatgt cagatatact aggataagtt
     2281 ttgtacataa taaatctcaa tctatttagg tattcatatt catcaatttg aatatctaat
     2341 tgattgagat ttctattcta aaagtttata aattttatgc ttacctttta aatataatca
     2401 tttttcttaa agattatctt atttattggt atatggaatt atattgttta ttattttata
     2461 atctcttcat catataaacc tattaaatat tatcctattt attggtatat ggaatcatat
     2521 tgtttattat tttataatct tttcatcata taaacctatt aaatattatc ctaatttatt
     2581 ggtatatgaa atcatattgt ttattatttt atagtctttt catcatataa acctattaaa
     2641 tattattcta tttattggta tgtggaatta tattgtttat tattttatag tcttttcatc
     2701 atataaacta ttgtattcta taaactgata catatccagc tgcagaagta cctgtcgtgc
     2761 ctgaaccaaa tgtaaaactt aaagtaacag ctgctgctct agcatcaact aaaaagctta
     2821 aacttacact tacatctgat gaagtaagtg tatttactgc ttttgcaata aagttatttt
     2881 gagctactcc attaaagtta gtagtaattg acataaatcc tgcaagtgaa agtgtggcac
     2941 gtataccgaa agatacattg tatatccctc caactgcaag atttatagta ctacttgttg
     3001 gaaaagttat attagttcca tttataaatg atgaattaaa tgtcactaat gtattattca
     3061 ctaaacttga agaggacact gtaaattgtg cattgtttgc tgctaacact cctgttgctc
     3121 ctgtcgcccc tgttggacct gttgctccat ttgctccggt tgctcctgtc gctccatttg
     3181 ctccggttgg gcctgttggt cctatcgctc ctgctactcc atttgctccc gttgctccta
     3241 ctgctccggt tgggcctgtt gctccatttg cacctgttgc tcctgtcgct cctgttgctc
     3301 ctgctactcc atttgctccg gttggaccgg ttggacctat tggacctgct actccattcg
     3361 ctccggttgc tcctactgct cccgttgggc ctgttgctcc atttacacct gttgctcctg
     3421 tcgctcctgt tggacctact gctccatctg ctcccgttgg gcctgttgct cctactgctc
     3481 cggttggacc tattgcccca gctactcctg ttgctcctgt cgctcctgtt ggacctacca
     3541 aaccatttgc tccggttgct cccgttgggc ctgttgggcc taccaaacca tttgctccgg
     3601 ttgctcccgt tgggcctgtt gggcctgttg gacctaccaa gccatctgga cctgttgctc
     3661 ctactgctcc tgttggacct acctctccat ctgctcctgt tggacctgtt gctcctattg
     3721 ggcctgttgc cccagttgtt cctgttgctc cagtcgctcc tatacttcct gttggacctg
     3781 ttgctcctgt atttcctgtt gggcctgtag cacctgttac tccatttgct ccggttgctc
     3841 ctgtatttcc tgttggacct gttattccat ttgctccggt tgctccggtt gctccagtta
     3901 gtccggttgg acctgttgct cctgttgctc ctgtattccc tgttggtcct gttattccat
     3961 ttgctccagt cgctcctgta tttcctgttg gtcctgtaga gcctgttatt ccatttgctc
     4021 cggttgctcc tttgtttcct gttggtcctg ttattccatt tgctccggtt gctcctgtat
     4081 tccctgtcgg acctgttatt ccattcgctc cagtcgctcc tgtatttcct gttggtcctg
     4141 tagaacctgt tgttccattt ggtccagtcg ctcccatatt tcctgttgga cccgttattc
     4201 cattcgctcc agttgctccc gtatttcctg ttggtcctgt tattccattt gctccggtcg
     4261 ctccggttgc acctctaggc cccgtcggtc ctgttggacc agtagcacct gttggccctg
     4321 ttggacctac atcttgatat aaacttggac ctgaaatatc actcatataa ttaatcctcc
     4381 ttttttaaag ttagagtaat actctataaa tattgagtat taccctatat aattatatga
     4441 atcgacaatt tcttatgtga taatgtatct atttgcttat atcaacatat atgctttgat
     4501 tcttgaattt cattactttt ttgtaaaatc ttttacaatt attaatacaa ttaaaaaact
     4561 catttcccat caattattta aaattttttt attatgttat aaaaaataga taattaaatt
     4621 gcataaaatt aatttaatac tactttaatt actttttaaa taaaaaaacc tcaacacgat
     4681 taataaaaat catattaagg catccacaaa attatataat tgcttatcta tcttcatcag
     4741 taacattgaa tatataagga acatttctat aataatcacc aaaatcaaac ccatatccaa
     4801 ccacaaactt atcttctatt tcaaatccac aataatctgg cactaaatcg acttttcttc
     4861 tgcttggttt atccaaaaga acacagcatt ttaaactagc aggattttta gcttttaaat
     4921 gttttaacac aaaatccata gtaagtgcag aatcagtaat atcgtctaca accaaaacat
     4981 catatcctgc tatatcagta gtcacatctg aaactacttt aacctttcca gtactttctt
     5041 cattgtttcc ataactagat gtagtcataa aattaactct aagtggtaag tttatatttc
     5101 taactaagtc tgcacaaaat ataaagctac cttttaatag agaaactacc ataagatttt
     5161 tatctttata atctttttct ataattgctc ctaattccct taatttatct ttaatttttt
     5221 cttctgaata caatacttcc catttttttg tttctatatc cataaaaaga cctccaattg
     5281 taataatcct tcttaatttt ataagagatt gctcactttt tcaatactct tattcaatat
     5341 tagtcaatat tattgagttt ttatgttcat tcaacaatta ttaacaatgt atcttatatt
     5401 ttaagtagtt catatatcca cactaaatta catactatat attttagaca aaaaaagaaa
     5461 aaacttgcac taacaagttt tttctattat acataaattt atacataatc atattttatt
     5521 agagggtact aattaaattt atttatgcta tttttgttat ccctcataat acaaaacata
     5581 ttataaagta ctagtcaact ttattcatat cattcattac atttaagatt atctcatctg
     5641 ttatagacat acctttgtca cttactctac ctaagttttg tatactttgc tcaacacttg
     5701 aaccaactat accatttagt ggtggtacaa aacaatcttg cttagctatt atagcacttt
     5761 gtatagctgc agatgctgca gaagataatt ttaatgcaca accagctttc gcaccgtcac
     5821 atatcattcc acttaagtca gctatcatat tttctatagc tccttctatt tgcttttcag
     5881 taccattcat aagccaagag ataccagcag ttgctccagt agaagcagca acaccacatc
     5941 cacatacagc agataatctt cctgtatagt tcttaatata accagttact agatgagata
     6001 tagctaaagc ttttgctagt ctttcatcag attgtgggaa ttttttatta taagcaacga
     6061 ttggaagaat tgctgttaat ccatgatttc cacttccatt tgaactcata acaggcattt
     6121 ttacccctgc cattcttgca tccgaagctc cagcagttaa catcattgca taatttataa
     6181 catcattacc taaaagacct tcttctatag actttttaat tccatatccg acaccaatac
     6241 cagttttttg ttttaatcca tattcagcca tctcttcatt catttttact ccatctagta
     6301 aaaattctat atctttaaaa tcaattcctt ctacattttt tattaattct tgtatagtta
     6361 ctgtatccat taaactttca gctttttctg ccacatcatt tgaagctgat acttttggtt
     6421 cattgtctaa taatacttct ccatcttttt ctaagaacgt aaaattatca tgtttagttc
     6481 ttattctcac tttagcaata tgattttttc cttttaacac aacttctata aatactttct
     6541 ctcttgtatc agcaggtgtt attgatagtg gagtattatc catataatcc tcagctattt
     6601 taacttcctc ttttgttaga gtttctaaca cacttaatcc attttcagaa tgtccaccta
     6661 ctatacctag agctgctgca atttttaatc ctaatctttc agtacctggt atacctacgc
     6721 acataccatt tttatagata ctaggactaa ctaacatacg attttcaact atttcttctc
     6781 ctaataattc ctttgccttt gcacatgcta gagctaaggc tactggttca gtacacccta
     6841 ctgctggttt aacttctgcc tttaacattt ccactaattc ttttcttata tctctcatta
     6901 tatataaacc tcccaattaa gtttagattt agtactcaaa taattaatta aataatttct
     6961 tatctatatt tatagcaaaa tacatgccat attttttata tctttttata tttttagtct
     7021 tatattctat aaccattggt atgactgctt ctatttatgt atttttttat ttacatagag
     7081 tatttatatt ctttaaaatg gataaacata tgacaatttc gcaaaaagac aaaaaaaagt
     7141 ctcaaaatga gattctatat cattttgaga cggctcaaat gtattatttt ttaacttata
     7201 aaaaccattt tttaattcat aaaaaaagat tctgcaaaac acttatagta taagtttaaa
     7261 gctttcttta aagttatgaa tttagaaaaa tttaaatttt atatagcttt ttattatatt
     7321 actatgaaat tatattgtat ttttcaattt ttctatataa tgtagctctt gatattccaa
     7381 gtgctttagc tgttaattct ttatcttttt tataatcttt gtacttattt aaagctttta
     7441 ttatctcaat cttctctagt tcatcaagtg gaattatcct atcgctttta acttctaact
     7501 cttctacaga ggtattctta attttttgag gaattacatt cattgtgatt attgaagaag
     7561 aagacatatt cacactatat tcaataatat tctgcaactc tcttatattc cctggccact
     7621 tatattccat catagcatca acaaccctgc tatctatgtc aataacattt ttatctaatt
     7681 tttttgaata ctctttaacc atatgcttga ttataagtgg gatatcttct tttctctctc
     7741 ttaaacttgg taattttata ggtataacat ttaatctata gtataaatct tctctaaaag
     7801 tgccattttg aaccattttt tctaaatctt tatttgtagc agcaataatt cttacatcta
     7861 ttgaaacatt tgatttactt ccaattttat taagttcctt ttcttgtaat actctcaata
     7921 actttgactg taaatgcaaa ctcatatctc ctatttcatc taaaaatata cttcccttat
     7981 gagctacttc aaacattcca agctttccac cttttttagc tccagtaaaa gctccctctt
     8041 catatccaaa taattcactc tctaataaat tatccggtat agcagcacag tttacagcta
     8101 taaaaggatt atctactcta ttgctatggt tgtgtatggc tcttgcaaat agctccttac
     8161 ccgttccact ttccccagta ataagtactg ttgatgttga tttagaagct attagggctt
     8221 cctttttaga atttcttata gctacacttt ctccaattat gttttccaat tttattctat
     8281 aatctttatt catcttattg tagtttttta tagcatctct tttatctata aaatcaataa
     8341 catatccctt taactcattt tttaatacta ttttattgat attgtatatt cccttcgaat
     8401 catatccata tcttttataa aaaaaactac aggatttgtc cttcttaaag ttatttatag
     8461 aaggtttctt tataaaatct aattcgacaa atatgttttt gccagttata ctatctttta
     8521 tattgaaaag ctctttaaat tttgaattat atttatcaac ttttccatcc acatcaatag
     8581 acacaacagc tttgtccata ttgtttaata gtgtctctaa ttttttcttt tctaattcaa
     8641 gctcataagt tttaatttgt gcttttaatt tattagatat taggtctgcc attttgccta
     8701 aaaagtttat aagaccactt ttattatttt ctataatttg tgcttgttct tttgtaaagg
     8761 ctataaggcc tataacacca tgagaatcgc catcacatat aataggacaa cacacctctg
     8821 caaactctac acaagcccca cttttatagc attccctaca tatatcacta ctctttgggt
     8881 catcaattag tattgtaatc tgttctgtaa gtgatttttt aaaagccgta tatttatcta
     8941 ctttctcacc tattttgtct atatatactc ctgtacctgc aatcctaaat aactccttat
     9001 ttactatagt tacatctata ttgagtactg atactatagc ttcagctata ttttgaatat
     9061 cagattttat atattctaaa cctatcataa tcatcattcc ttatttttct ttaacataag
     9121 tatttgtctt atttctttaa gaatcaagta tatcttattt aaagtaaatt ggattgacat
     9181 caggattaca aagagcataa caattattat taactcataa tttatttcca tctaaacatc
     9241 tccttataac aaaagactag gcttaaccta gtcttttata ttatatccat atttatattt
     9301 taactcattt atcttctttt tcccacataa atatatttta atttatttga ctctttaatc
     9361 ataccatcaa agtttaatct tgaaaatata ttaaatactt catgtggata gtgaatcttt
     9421 gcaacagaac cacaaaattt atgtttaaga tagtttaact taacttttaa attctttaaa
     9481 tttaaatcct ctaatataac ctctccattg ccctttaaca ctctttgtat ttcagatgaa
     9541 gctttttcac aatctgtaat aacattaaat tggtcaacta ttattatctt gttgaactga
     9601 ttatcatcaa atggtagaaa ctctaactta cctttaacta cattgcaatt ttcattatac
     9661 actagagaat aacagacatc ttcataatta ctattctcca gtatagttac agaagttcca
     9721 agacctctca atctcttgcc taggtttcct atatgaccaa caagcaatat tttatcacct
     9781 acattatact caattgtatc caaaaaacat tctaattcat cagatgtata tttagcttta
     9841 accggctgtt tatttatctg acataatatg cttttcacaa tgcttcacct cttcatttcc
     9901 tcaattataa attatgtaca gattacatta taataaatgg cgagcaacta ttcaagagat
     9961 atttcattag tattttttta aacaatcttt atacatttta atatgatatt ataccaaatt
    10021 tattaggatt ttattcataa aaatcagtct atttttcatg tttattcatt gttattttca
    10081 tccaattttt ttattttcga tatggatact tcatatgcca tttttttgac cacattattt
    10141 tcatctattt ttttctcata ttctctactt tgaaccctac cccaaagctg tattctatca
    10201 ccaaccttta gattctttgc aaatttagca tttctacccc aaactattga tggtatataa
    10261 tcagatttat tataaggtct gtttatagca actaataaat cggttatttc ccttcctaaa
    10321 ggtgtcttcc tatacacagg ttccttacat acatatccat ctaaaaatat actattaggg
    10381 tctttatttt cctcgtctat gctttttatt tctctgacaa acactgtaag cactaatcta
    10441 tttttattat ttaatgtttt gttatatgat cttaattggc ctacgacatt gactaaattt
    10501 tgtttatcaa ggtcaatatc ttggagaagt ctttctgata cagtcattgg aagtatatca
    10561 aaagaatcgc ttagtctgtt tatttttatt ttcatattat aaaatttttc tccaaatatc
    10621 tcatggctaa attctagctt attgtctaac tcccctctta agtttactac gttattctca
    10681 tctttaacag ctatcatatt ttatccctcc acaattgtta attcttatat ttctggtatc
    10741 agcttatata ataaatatat ttataaggga tgtattttat tacaaatctt tgattgctgt
    10801 ttaaaagttt ttatttagtt ataaatttca tttaatattt cacttttata attataaaat
    10861 tattatcttt ttgtaccaca tatactaatt aaactaccta tttcagtttt atattaatta
    10921 taaaaatcct attatatagt taataagtca tatataactt aaatttattc actctatata
    10981 agcaacttca acgaattaaa tttattcaaa taattcagat gaatattgag tcattataaa
    11041 cttatttttc ttaattataa gttatattag acttattaca ggttatattt ttattaatct
    11101 gtattaata
//
LOCUS       DAEOTL010000113        10720 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEOTL010000113 DAEOTL010000000
VERSION     DAEOTL010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.115"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            160..1311
                     /locus_tag="KRH82_003483"
     CDS             160..1311
                     /locus_tag="KRH82_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBG8656738.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1357..2532
                     /gene="thiI"
                     /locus_tag="KRH82_003484"
     CDS             1357..2532
                     /gene="thiI"
                     /locus_tag="KRH82_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBG8656739.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2688..3491
                     /locus_tag="KRH82_003485"
     CDS             2688..3491
                     /locus_tag="KRH82_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBG8656740.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3734..4375
                     /locus_tag="KRH82_003486"
     CDS             3734..4375
                     /locus_tag="KRH82_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBG8656741.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
     gene            5788..7458
                     /locus_tag="KRH82_003487"
     CDS             5788..7458
                     /locus_tag="KRH82_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBG8656742.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHVDIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(7580..8314)
                     /gene="pflA"
                     /locus_tag="KRH82_003488"
     CDS             complement(7580..8314)
                     /gene="pflA"
                     /locus_tag="KRH82_003488"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBG8656743.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(8474..10705)
                     /gene="pflB"
                     /locus_tag="KRH82_003489"
     CDS             complement(8474..10705)
                     /gene="pflB"
                     /locus_tag="KRH82_003489"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBG8656744.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
BASE COUNT         4065 a         1293 c         1764 g         3598 t
ORIGIN      
        1 ctataaaaat ttgtaataaa gtgaaaaaac tagcttttca tgaaataata ttttataatt
       61 taagattgtc tttttaataa agattaacaa aaaaaatact ataattagtg gtataatagt
      121 tagagttgaa gattttaaat aaaggtaggt gtaattaagt tggaaatata cttagacaat
      181 agcgcaacta caaaacctta tcaagaagtt atagataaaa tggtttatgc acttaatacg
      241 gaatatggaa atccttcttc tgtccataga aaaggtgtag aagttgaaaa agctataaaa
      301 gaagtaagac aagatatagc taaatctcta ggagcgaaag aaaaggagat ttattttaca
      361 tcaggtggta cagagtgtaa taatactata ataagaggta ttactagttt aaataaaaaa
      421 agaaaaaatc acataatatc tactaacata gaacatcctt ctgttttaaa tacattaaaa
      481 gatttagaag aagatggttt tgaagtaact tatttagagg tcggaaaaga tgggaaaata
      541 aatatagagg atttaaaaaa tgcgataaag tcaactacat gcttagtaag catgatgcat
      601 gttaacaatg aaataggaac tatacagcca ataggtgaag ttggaaagta tttgaagggt
      661 ttaaaagaaa aaatttattt ccatgttgat gctattcaat catatggaaa aattaacttt
      721 agaccatcta aatacaatat agattttatg agtgtaagtg cacataaatt tcatggtcca
      781 aagggaattg gatttatgta tataaaagaa aataatcgcc ttaagcctat gttaacaggt
      841 ggtggtcagg aaattggaat taggtcggga acagaaaatg tacctggaat atatggtctt
      901 ggagaagctg ttagaatact aaacaaagat ttagatgctg ttatttcgaa agtagataac
      961 ttaaaaaata tattaaaaaa tgaaataatt gataatatag aagatataaa aatcaattct
     1021 ccagaagatg gagtatgtca tatattaaat gtatcattta gagggacaaa aggagaagtt
     1081 ttacttcatt acttagagca aaaaggtatt tatgtatcaa ctggctctgc atgttcttct
     1141 aaaaagaaag gtagttacgt attaaatgct ataggtctta caaatgaaga aataaatgga
     1201 acaataagat ttagtttatc tgatatgaat acagaagaag aaatgttaga agctgtgaaa
     1261 gttttgaaag aatcaatttg tgacttaagg tcaataatga aaagaaaata aagaatactg
     1321 tataaatagt gataataaat tagtttaaga ggtgaaatgg tgtataatat attaatagta
     1381 aagtatggag aaattggagt aaaaggaaag aatagatata tatttgagaa taggcttata
     1441 agaaatataa gaaatatgtt aaaaccaatt ggaagattta atgtatataa agagtatgga
     1501 agaatatatg ttgatttaga agactatgat tatgaagaag taattgaaga agttagaaaa
     1561 gtatttggga tagtgggtgt gtgccctgga gtaagagcta aaaaagatta tgatacatta
     1621 aaagaaatag ctttaaaaat gttagaagaa aaaatagagg ctggatataa aacttttaag
     1681 gtagagtcaa gaagaggaga taagtctttc ggattgactt ctcaagaaat gagtatggat
     1741 ataggtggat acttattatc aaaggtagga gataggatta atgttgatgt aagaaatcca
     1801 gaagttaaaa taaagtgcga atacagagaa tttcatacta tggtctatag tgatactata
     1861 cctggatatg gtggattgcc acttggaacg aatggtagag ctatgtctct tttatcagga
     1921 ggtatagata gcccagtagc tacatggatg gttgcaaaaa gaggtatgga agtagaggca
     1981 gttcactttc atagttatcc atttacaagt gaaaggtcac aggaaaaagt taaggattta
     2041 gctaaaatac tggcaaaata ctgtggtaga gtaaggcttc ataaagttaa tatcttagaa
     2101 atacaaaaag caattggcga gaattgtaat gaagaagaag ctactattct ttcaagaaga
     2161 tttatgatga ggatagcaca gagactttct gaaaaaagac attgtgatgc tttaattaca
     2221 ggtgaaagta ttgggcaggt tgcatctcaa actatacaag gacttacttg tactaatgcc
     2281 gttgtagact taccagtgtt tagaccactt atagcaatgg ataaatcaga tatagttgat
     2341 atagccaaaa aaatagggac ttttgaaaca tctatagtgc ctgaagaaga ttgttgtagt
     2401 gtattttctc ctagaaagcc cgtcactaaa cctagattag agaaaataga aaaatctgaa
     2461 acagcacttg acattgaaaa attagtacag gatgctattg acaaaataga ggtagaggat
     2521 attgagtttt agcatacaag ttatttaatt attaaattga atattgagta tattagtagt
     2581 tctgtaagta tattagtagt tctgttgaaa ggatttatgt agacaattta ttaatatgta
     2641 gtatttaaaa ataagtacta taattttatt taatgggaat gattattatg aataaaaagg
     2701 gttttacatt aattgaattg ttggtagtta tatctataat aggaatttta gttatagtag
     2761 ctgttccagc gttatttaga aatatagaaa aaagtaaagc agttacatgt ctttctaata
     2821 gagaaaatat aaagactcaa attgttattg caatggctga ggaatcaagt aaagacaaga
     2881 atgaagtcat aaaagaggta ttagaaaaca aagatggtaa gtactttgaa acagaaccaa
     2941 agtgtaagtc aggtggaata tattcagcaa cgtttgatga tggttatgat ggaataactg
     3001 gaatagaaag cattgcaaaa gtgtatgtta cttgtacaaa acatccagac ggtgttgaaa
     3061 tggctaggga tgtgcatcaa agtatgaaag atttgattgc atcatttgca caagaccctt
     3121 ctataatacc aggagcttca aagggcaatg atgattttag aaaatattta ttagacaata
     3181 aatataaaaa tgggtggcct acaattccag atgaatttaa ggcaaaatat ggattaagta
     3241 aggatacact atatatacaa ccatatgcat ataatcctac taaatctgat gctactgtag
     3301 ttgtatttgc aaataataag actggaggta attggtatac ttccctagtt tacgattatg
     3361 atgaaggtag atggtataaa ggtaaaaatg gtatttctgt tgcaggtagg tcatgggatg
     3421 ttgacacaga tagtgttaag tctgtaaaaa cagagattca ttctaaagag ggatggggtc
     3481 ctttaaatta atatatcatg ttttattaat ctggtattga ttaaactata gaaaagagca
     3541 gtttctatag atgacgaata ccagattttc atttatatat ataattgaga tatattaaaa
     3601 gtgtttatat ttttaagtct tcacatacaa gctaaaaata attataataa tattgtaaag
     3661 aaatttaatt ataagattaa ttttctgaag atttagtatt tgtactaaga aatacataaa
     3721 aaggggaata gatatgaata ataattttca agacaaccaa acaataaatt taatacaaag
     3781 tcgtagaagt atacgaaaat ttacgacaga acaaattagt gatgagcaag taaacacatt
     3841 attacactgt gcatttgcag caccttcagg atgtaataaa cagccttggc acataactgt
     3901 tgtgcaagac cagaaacttt taaaagagat tagtgatgat actttatcta ggattcatga
     3961 ggtgagtaat gttgagataa ataaaaactt taagttattt tatggtgctc caaccgtttt
     4021 atttatttct tatgatgaaa gtagttcatg ggctccatat gatataggaa tacttacagg
     4081 gaatataaca acagctgcac aagcactagg gcttggaagt tgtataatag gaatggttag
     4141 aggtttattt acacctgttg aacaagggga tattgaaggt cttgtgagtg tattggataa
     4201 agaagatgta aaagaatcag agtcaataaa gatgaagttt gatacaaata aaaaatatag
     4261 agaactactt gatataccag aagggtattc tgtaccattt ggtattgctg taggtattcc
     4321 agatggaaat ttaccaaatg ctagagaggt agtttataaa gtttccagag tttaggatga
     4381 agtattgcaa gaaacaatca gttacttgaa gaattaaatc agtaatatac aaataaattg
     4441 atggaagagg aagctattta aaaagtagtt tagatttttc gttgtaaaat aattaaataa
     4501 agaataaggt gataagtatt ttatttatta tcttattctt ttttattttt gttttgtaga
     4561 atgataaaaa taaggattaa gtgtaataaa atagaaaaca agtatgttaa ttttaagtat
     4621 atgctttaaa atttatccaa gttaaaaatt taagatatct tttcagtata atggaaaaaa
     4681 tgtcaaaata ttgaaatagg gaaaaaatag tgatataata agaaaaaata gagaaaaaaa
     4741 gtaaccctta gttataaaaa agttactatt tattgaaaat ttagatattt ttctaaaaat
     4801 tatctatgtt aatagttaaa tttatgaaca ttttttgttt ttatgttagg atatttctta
     4861 gaaatgaaat acttcttaat ttgatttgat atgtatattt ttatagctat tttattataa
     4921 aaaaaaagaa ccctttttat aacaaatgga aactatggat gtaataatta aaataaaaaa
     4981 tattattttt atttataaac attgacattc taattttgta gtgtaatcgt attttttatt
     5041 aattcttaca aaatcaatga aaataagtat atccatttta aagtacataa atttaaaaat
     5101 ccagaaaaat atacttaaat tatgtaagta aaagaggggt tgaatcagtt gaaaatgtaa
     5161 tattagtaaa tagtacatca atcctatata ccctgtaagc aactctattt tcatgtacta
     5221 aaaatgtacc tattttatta actgaaaaga ataaattaaa tgtaagtaca taagaagata
     5281 gaaaaaatta aaaacaaaaa atatttatat aaataaatat aaaaaatgat ataatcccta
     5341 ttaaaaaatt tatagatgat gaagaaatat caaaatctta tattatagga agagacactt
     5401 ctttgccaaa atctatagaa aaacaatacc aaatccaaag agaataggcg gagaaaaaaa
     5461 taaaataaat tcaagagtaa tagaaaagtt ttatagaata aagaactgat aactctttat
     5521 ataacgaaaa atagaatttt aagagaaaat gatttaataa atgatttaac atggtgtttt
     5581 agcaggtaaa aataaatcac cagtaatgat tatagaaaaa ttactttatg aatctcaaaa
     5641 aacttagtta agagtaagag atttgataag ataactaaag ttggggaaat gtgtttgatg
     5701 agacaaaaaa ttagtaaaat agtataatct agataaggat attttgttga ttaaactaca
     5761 ctaatagtaa tattgtaggg ggaaaagatg agagaagaat cgaactcttt aagtttagac
     5821 catatagaaa ttttctttga acttttatct caaagtacag aagattatat atttttttgg
     5881 gatataaata ggaataaatt taaaatttct tcagcaattt ttgatgaatt taacttaagt
     5941 aaagagatag aatctgattt agtcaattgt tggagtaaaa ttgtttatcc ggatgatgtt
     6001 caaatatgga aagatgatat acaagaatta ctacatggaa aaaaaggtga gcacaattta
     6061 gaatataggt tgattaataa atataaagaa atagtatgga tttcttgtag aggtaaagtt
     6121 tatgtgtcgg atgacccaaa aactatattt ctagttggga gaataaagaa tattggtgaa
     6181 aaaaataaat ttgattctat cacaggaacg tggaatagag aacaatttga acatagaatg
     6241 aattatctta taaaagagaa aatttataaa aatggtgcta tgtttattat ggatattgat
     6301 aattttaaaa atataaatga aaaatatgga cattcttatg gtgacaaagt attgcgtgca
     6361 attgctactg aagtattaga atatcttcca aaagatgtaa gattgtatag gttagatgga
     6421 gatgaatttg cattttttta ccctatgtgt actaaagaaa ctatagagaa aatatatgaa
     6481 aagatacaga tgtatacaaa tactcagcat gaaattgaat caaataagta ctattgcaca
     6541 gtgactgcag gcgttgctat gtatccagaa gatggagata attatttaga tttatttaaa
     6601 catgttgata ttgcattgga tatagcaaaa attagtggta aaaatagaat taagtttttt
     6661 tcacaagagc tctatgaaaa taaactaaag gtaatttcaa tgcaacaaaa actaagagag
     6721 tgcgttgaaa ataattttaa tgactttgag ctgttttttc aaccccaggt aaatgctgtt
     6781 acaaaagagg taataggggc agaggtactt ttaagatggc attcgagtac ttatggagaa
     6841 gtatctcctg ttgaatttat accaatacta gaacagagta atttaattat accagttggg
     6901 aagtggatta taaaagaagc tgtaaaacag tgtaaagaat ggcataaaat aaatccagac
     6961 tttaaaatat ctgtaaatgt atcgtatatt cagttaaagg aagatttttt tagagatttt
     7021 atagtagaat gtttagtaga gtatcaatta agacctgaat ttttaatttt ggaattaaca
     7081 gagaattgtt ggataccaga tataaattta ctaaatgata aatttattag tttaaagggt
     7141 ataggagtat atattgcgat agatgacttt ggtacaggat attcatcttt aaattacctt
     7201 aaagaactgt ctgttaatat aataaaaatt gaaagaagtt ttgttaagaa tattacatat
     7261 aatagttatg aatatacttt tcttgaatat atcattaaat tagctcatat tataaattta
     7321 aaagtttgtg ttgagggaat agagtcttat gaagagtatg atatagtaaa aagcttaggt
     7381 gtagatatta ttcagggttt tttatttgga agacctgtaa gtgcctctga attttataaa
     7441 tttcagctat caaagtgatg tatataaaat gagatatata gtatataaaa atagggcaaa
     7501 gtggaagttt tgaagtttat taaaaattta cactttaccc tattttgtta tgtcttctat
     7561 aaaggattaa tatactacac taactattat atactttcac tccaaattta gagattattt
     7621 cactagcttt ttggacatct tccttagtgg catcaggaac atcttttagt tcataatcga
     7681 tacctaaact ttcccatttg tgtattccca tagaatggta tggtagcaat tcaaatcttt
     7741 ctacattttt caatgtagct acaaattgac ctagtttttc taaattatct atatcatcag
     7801 taatgccagg aactaaaaca tgtcttatcc atacaggaat atttcttgat tctaagtgtc
     7861 tagcaagttt taatgcctta tccataccaa caccagtcaa atcaatagat ttttcctcaa
     7921 ccatatgttt taaatcaagt aaaaccaaat cagtattatc taaaactggg tctatagttt
     7981 ctatatctac aaatccagat gtatccaagc aagtgtgtat atcattttct tttgcttttt
     8041 taaataattc acttaaaaat tctggttgaa gagtggattc accaccagag gcagttatac
     8101 ctccaccaga aaacttcata aaagaagtat acttaagagc atccgttatt atttcatcaa
     8161 ctgtgtattc ttttcctgat ttaatatccc atgtatccct gttatgacag tatttgcatc
     8221 taagaggaca cccctgaaaa aataatatat atcttattcc tggtccatct acagtaccaa
     8281 acgtttctat agaatgtatc tttcccttaa tcatagagtt cacctcacaa tatattttaa
     8341 taaccttatc aatagttata atatttctct aaaaaaggcc atcttatacc agaaataatt
     8401 caaatataag atagcctttt atttttattt tttacacagt agtaatctta gttaaagtat
     8461 aaaaatttaa agactaagcc attttaccgt ggaatgttct gtttataaca tctaattgtt
     8521 gctctttagt taattttatg aagttaactg catatccaga tactcttata gttaattgtg
     8581 gatattcttc tggatgttcc atagcatctt ctaaagtagc tctatcaaat acatttacat
     8641 ttaagtgatg agcattttga gcgaagtatc catccatcat tgcagaaaga ttgtttattc
     8701 tttcagtcat atcttttcct aaagcagcag gtactataga gaaagtatta gatataccat
     8761 cttgagcatg ttcatatggt aatttagcaa ctgaagataa tgaagctaaa gcaccattag
     8821 tatctctacc atgcattggg ttagcaccag gagcaaatgg agcaccagct cttctaccat
     8881 ctggtgtatt accagttttc ttaccataaa caacatttga agttattgta agtatagatt
     8941 gagttggata agaatttcta taagttttat tctttcttat tttattcata aagctttcaa
     9001 ctaactctac agctatacta tcaactctat catcattatt tccgtatttt ggataatctc
     9061 cttctatttc aaaatcaaca gctattcctt gttcatttct aatagtttta accttagcat
     9121 gttttatagc agataatgag tctgcacaaa ctgataatcc agccatacca caagccatag
     9181 ttctaaatat atctctatca tgtaatgcca tttctaatgc ttcataagaa tatttatcat
     9241 gcatataatg tattacattt aaagtattta catataatgt tgctaaccaa tcagtgaatg
     9301 gttcaaattt actcataact tcatcataat ctaagtactc agaagttata ggttcaaatc
     9361 ttggtccaac ttgaacacca gatttctcat ctacaccacc atttatagcg tataataaag
     9421 ttttagctaa gttaactcta gctccaaaga actgcatttg tttaccaatt ctcattgcag
     9481 atacacaaca agctatacca tagtcatctc cccagtatgc tctcattaaa tcatcatttt
     9541 catactgtac tgaacttgta tctatagata ctttagaaca gaaatctttg aatccttgag
     9601 gtaatttagt tgaccataga actgttaagt ttggctctgg agaaggtcct aatgtatata
     9661 gagtatttaa cattctaaat gagtttttag taactaatgt tctaccatct attcccatac
     9721 ctcctataca ctcagttacc caagttgggt ctccagagaa taggttattg taatcaggag
     9781 ttcttaggaa cttaaccatt cttaatttca taacaaaatg gtccatatac tcttgtaatt
     9841 cttcttctgt tacgattcca gcttttaaat ctctttcaaa gtatatatct aagaaagtag
     9901 atgttctacc taaagacatt gcagcaccat tttggtcttt aacagcacct aaataaccaa
     9961 agtataacca ttgtacagct tcttttgagt tagttgctgg ttttgagata tcaaatccat
    10021 aagattcagc cattttttta agttcattta aagctgatat ttgctcagtt atttcttctc
    10081 ttaatctgat aacttcctca tccatgcaag aaacttctaa tgatttcttt tgctcatttt
    10141 tatcttctat taaagcatca acaccgtata gagcaactct tctgtagtca ccaattattc
    10201 tacctctacc ataagcatct ggaagacctg ttattatacc agattttcta gcagctctca
    10261 tttctggagt ataaacatca aaaactcctt ggttgtgtgt ttttctgtat ttagtaaata
    10321 tatcttttat ttctgggtct aattcatatc caaaagcttc gcatgaattt tcaaccatct
    10381 ttataccacc atatggcatg acagctcttt ttaaaggggc atccgtttgt aacccaacta
    10441 ttgtttctaa ttctttatct aaatatcctg gagcatatgc agctattcca gaaacagttt
    10501 ttgtatcaac atctaaagta ccaccatttt ctctttcttt tttaaatagg accattgctt
    10561 cgtcccataa ttttttagta ttttcagtgg caccagctaa gaaagagtca tttccctcat
    10621 atggagaata gtttaattgt ataaactctc taacatttat ttctttagtc catcttcctg
    10681 ttttaaatcc ttgccatgca ttcattaagt atttcctcct
//
LOCUS       DAEOTL010000114        10689 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEOTL010000114 DAEOTL010000000
VERSION     DAEOTL010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10689
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.116"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            162..512
                     /locus_tag="KRH82_003490"
     CDS             162..512
                     /locus_tag="KRH82_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBG8656745.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            531..2174
                     /locus_tag="KRH82_003491"
     CDS             531..2174
                     /locus_tag="KRH82_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBG8656746.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFTKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2255..4312
                     /gene="recG"
                     /locus_tag="KRH82_003492"
     CDS             2255..4312
                     /gene="recG"
                     /locus_tag="KRH82_003492"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBG8656747.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4371..4925
                     /gene="rsmD"
                     /locus_tag="KRH82_003493"
     CDS             4371..4925
                     /gene="rsmD"
                     /locus_tag="KRH82_003493"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBG8656748.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4927..5424
                     /gene="coaD"
                     /locus_tag="KRH82_003494"
     CDS             4927..5424
                     /gene="coaD"
                     /locus_tag="KRH82_003494"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBG8656749.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5428..5952
                     /locus_tag="KRH82_003495"
     CDS             5428..5952
                     /locus_tag="KRH82_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656750.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6296..8215
                     /locus_tag="KRH82_003496"
     CDS             6296..8215
                     /locus_tag="KRH82_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBG8656751.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINKQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8228..8515
                     /locus_tag="KRH82_003497"
     CDS             8228..8515
                     /locus_tag="KRH82_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBG8656752.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8648..9907
                     /locus_tag="KRH82_003498"
     CDS             8648..9907
                     /locus_tag="KRH82_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBG8656753.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9910..10650
                     /locus_tag="KRH82_003499"
     CDS             9910..10650
                     /locus_tag="KRH82_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBG8656754.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
BASE COUNT         4312 a         1131 c         1989 g         3257 t
ORIGIN      
        1 tatatactat agaagaaatt ttatccaaaa acttttctag gtttaaatta taccatattt
       61 atagtatgat atgattataa ttttatataa taaataagta aaaatagtaa aaaataaatt
      121 aagaaatgtt tttaataaaa ataagcttaa gggggtcaac catgagtgca aaggtaacga
      181 atcaatatgg aaatatagaa atagataatc aagtaatagc tcaagtcgta tatagagctg
      241 caatggaaag ttatggctta gtaggtttag catataagtc taaaggaata gtagagctat
      301 taaaaggcga gaacgcaact aaaggtgtaa gagttgagga agtagaagaa gatgccatag
      361 caatcgaact ttatgttata atacaatatg gtacaaatat atctactgtt gccaataata
      421 taatagatag agtaaaatat gtagttgaaa aaatgactgg cgtaagagtt actagaattg
      481 atattaatgt acaaggaata agagttaagt aatttcatag gaggaaacaa atgattcaat
      541 atatagatgg taaaaggtta agggagatgt ttatttcagg tgcaaacaat ctccaaaaca
      601 ataaagagtt agttgacaag ttaaatgtat tccctgtacc agatggagat acaggaacta
      661 atatgtcatt aacaatatct tatgccttaa aagaattagc aaaagttgaa aatgataata
      721 tatcagatat cggaaaagca ttatctaaag gttctttaat gggagctaga ggaaactcag
      781 gagttatact ttcacaaata atcagaggta tagctaaatc tatagaagga aaaagtaaat
      841 tatcaacaga agatttagca aaagctttta aaaatggttc agacacagca tataaagctg
      901 taataaaacc aattgaagga actatactta ctgtagttag agaaagtgga gagtttgcaa
      961 taaaaactgc gaaaaaagag aaagatgtag taaagttttt aagtatgctt gtgaaggaat
     1021 caaattcttc attagaaaga actccagacc ttctaaagaa tctaaaagaa gctggtgtgg
     1081 ttgactctgg tggaaagggt cttgtactta tatatgaagg aatgttagct tctataaaag
     1141 gcgataacat agaaataaaa aatgttgacc tagatactaa tatttcaaca agtatggatt
     1201 ttacaaagag tactactagc acagatgata taaaatattg ctattgtaca gaatttattt
     1261 tagaaagttc taaggtagaa gatactaaaa taagagacat aatgatggct tatggtgata
     1321 gcctagcagt agttggagat gatggagtca taaaggtaca tgtacacact aatgacccag
     1381 gaaatgtact tcaagaagct ctaaagtacg gtcaattatt aactataaaa atagaaaata
     1441 tgaagttaca acatgaaaat acattactgg atgtagaaga aaagaaagaa aatgatagtg
     1501 aacctttaga agaagaaaaa gagtttgggt ttatagctac ttctatgggt gaaggtttgg
     1561 caaatatatt taaagatttc ggagttgacc atataataga aggtggtcaa actatgaatc
     1621 caagtactga agattttatg aatgctataa agcatataaa tgctaaaaat atatttattt
     1681 tcccaaataa cagcaatata ataatggctg ctaatcaggc aaaagaattg agtgataaaa
     1741 atataatagt tatacctaca aaaaatacgc ctcaaggatt tgctgcatta gtaactttta
     1801 atggagaatt aagtgaagat gaaaataaag aagctatgat gaatgcttta aactcagtta
     1861 aatcaggtca agtaactttt gctgttaggg atacagtgat gaacgaaatt gatgttaaag
     1921 aaggtaatat aattggaatt gcagaaggga atttattatc agcaggagat tatgtggatg
     1981 aagtaacatc aaaccttatt gaaaagttgg ttgatgaaga tactgctata ataacattat
     2041 tctttggtga agatgttaca gaatctcaag caaatgaact acgtacttct ttagaagaaa
     2101 agtttgaaga tgtagatgta gagttatatt atggaggaca acctctttat tattacttaa
     2161 tttcagttga ataatgatta taagaacctg tatgaccaag tagcttttat aaaattggtt
     2221 gtacaggatt tttgtgtagt aggtgatata tttgttggat ttatataaag atgttcaata
     2281 tgttaaggga ataggaccta aaaaagcaga taaattaaat aaactgggta tatttacact
     2341 aaaagaccta ttgtattatt ttccaagaca atttgaagat agaaataatc taaagaaaat
     2401 agcacaatta gaagatggtg agaaagttac gataaaagca gtaatatcaa gtataaatac
     2461 atttagccca aaagaaggta tgactttaac aaagattgat gtaaaagatg agacaggctc
     2521 ggctaaatta gtgtttttta ataagagtta tataaaaaat acttttcgtc caggagattc
     2581 aatattagtt tttgggaagg ttaagaaaaa atttaataac ttagaactta catcatgtga
     2641 attagaatat cttactaatt cacctaagaa tacatgtaga tttatgcctg tgtaccagct
     2701 tacatacggt gttacaaata aagaaattat gagtataatt agaacagtac ttgaagataa
     2761 agaattaatt atacaagaat atatgccaca aagaattata gaaaaatata ggctatgtag
     2821 tatagatttt gcagttagaa acatacattc accaagtagt aaggaatcat taaaaatagc
     2881 tttatataga attgtatttg aagaattact tatactacaa ctagggttgt ttgtatttaa
     2941 aagtggcaga aataaagaag atggaataaa gtttgaaaca agtaaagact taaaaaaaat
     3001 aataagtgct ttaccattta aactgactaa agctcaaaac agggcattag atgaaattat
     3061 acaagatatg aatttagaga aaataatgaa tagattggta caaggtgatg tagggagtgg
     3121 taaaacagta gtagctctct tagcacttgc aaattgtgtt ttaaatggtt atcagggcgc
     3181 tttgatggca cctacagaga tattagcagg gcaacattat atttcactta ctgagtctct
     3241 aaaagatttt ggaataaatg taggtctatt aataggtagt cttacaaaaa aacaaaagga
     3301 tacagtattg gaacaaataa agaataatga gattgatata ttaataggta cacatgcact
     3361 aattgaagat aaggttgaat ttaataatat tggtttagtt ataacagatg aacaacatag
     3421 atttggtgtt atgcaaagga gcaaactttc attgaaagga gcaaatcctg atatattagt
     3481 aatgacagca acaccaatac caagaacttt agcacttata ctctatggag atttagatat
     3541 ttctattata gatgaacttc ctccaggaag acagccaata gaaacaattg ctattgaaaa
     3601 aagtaagcga gatagagcat ataataacct tgtaagaaga gaggttgaat caggaagaca
     3661 agtgtacatt gtatgtccct tggtagaaga aagtgaagcc atagaagcca aatcagcagt
     3721 tgaacttgtt gaggagttaa gagcagaata ttttcacgac ttaaggcttg ggttgcttca
     3781 tggtaaaatg aagtcaagtg aaaaagatga agtaatgaga ctttttaaaa ataaagaaat
     3841 agatatttta gtttcaacaa cagtaataga agttggtgtc aatgtgccaa atgcaacatt
     3901 aatgataata gaaaatgcag aaagatttgg acttgcacaa ttacatcagc ttagagggcg
     3961 agttggaaga ggtagtcata aatcgtattg tgtactaatt tatgattcta aaacagatgt
     4021 atgtagacaa agaatggcta taatggaaga gaccaatgat ggttttaaga tttcagagaa
     4081 ggatttagaa ataagaggac ctggggaatt ttttgggaca aggcagcatg gtcttccaga
     4141 acttaaggta gcaaacttgt ttaagcatat aaaaatactg aagttagcac agcaagaagc
     4201 tcgatatata ttgggtgaag ataataatct acaattaaaa gaaaacatgg cactcaaaaa
     4261 agaaattata gataaattta aagatacatt gaaagaaatt tcattaaatt aattttaaat
     4321 tgtgttaaaa tattactaat gtaataatgt gctgaaggga gattgtcata ttgagagtaa
     4381 tttcaggaaa agcgagagga ttaaaactaa atactccaaa aaatgaagat gtaaggccaa
     4441 ctacagatag agtaaaagag tctctattta atatgataaa ttcatatata atggaaagtg
     4501 aagttctgga tttatttgct gggactggtt ctttaggaat agagtgctta tctaggggtg
     4561 ccaagtcatg tacttttgta gatatcagta aggaaagcat agatattgtt aagtccaata
     4621 taaaaaaggc aagagttgaa agtgaaagta ttattttaaa ccttgatttt aagactgcaa
     4681 tagataaact taaattacaa aatagtaaat ttgacataat ttttatggac cctccgtatt
     4741 ataaaaatat gtttatagaa gctattgaaa aaattgataa ttctaatcta ttgaacgaag
     4801 atggaataat agttgtagaa catgatacga atgatttatt tccagataag atatgtaaat
     4861 tggagaaaac tagagataag aaatatggaa atactacatt aactttttat aagatggagg
     4921 cataatatgg aaaataaacc tagaaaagct atatttgcag gaagttttga cccaattact
     4981 aatggacatt tagatattat ttgcagggct tcgaagttat ttgacgaatt acaaatagga
     5041 gtattaaata atcctaataa aaagggtcta tttagctttg atgaaagagt aaaacttata
     5101 gaaaaaagta caagccattt aaataatata aaagttgtga cttttgatgg tttattaata
     5161 aattactgtc aggaaaatgg gattggagca ttagttagag gtgtgagaag tggtgctgat
     5221 gttgattatg aacttcagat ggcacatatg aatagagagc ttaatccaga tatagagact
     5281 ataattttac caagttgtac aaaatattca tttataagtt catctttaat aaaagaggtt
     5341 ttgctctttg atgctgatat aaaaaatttg gttccaaaga ttgttttgga agaattaaag
     5401 aaaaaaacta gtgggggtaa ttgatatatg aagatagatt tagaaatgat tgaactattt
     5461 gagcagttag aggagatatt tagaagtgct tctacaatcc ctttctcaca taaatgcaca
     5521 gtggataaag atgaggtttt agcaataatt aatgatataa gaactttaat accagaagaa
     5581 gtaacacagg cagtatggat taataaagaa agaaataaaa taataagtca agctaagcaa
     5641 gatgctacaa atatagttga acaagcgaaa aaagaagctg agagaataca acaagaatat
     5701 caagataata tagaggaatt aaagaaaaat tctgaagatg tagtaaaggc atatgtagaa
     5761 tccagcgaac ctgttgttca agcagaccaa agagcaaaag atatagttga tagagctgag
     5821 agaatagcca atgagataag aattgggtca attgaatatg cagaggatgt gctttctagt
     5881 gttgagtata atttaagaga aatattagaa gaagtaaaaa gagataaagc tgaacttaga
     5941 cctaaaaaat aaattttaaa taaataaaaa tggagctatc acacaaaaaa ttccaattta
     6001 tgtgtgatag ctctctttta atatagcaat tttttgttat ataattgtgc tttttagatt
     6061 acttatatct tattttgata ttataatgta gtttaatctt ttatttgttg aaatcaactt
     6121 atttatttgt ataaataata taggttattt tcaaattttt ttaataattt taccactgtc
     6181 ttcttttaga ttagagttag actgtgcaaa attataaaat aatactaaat catgtgcaat
     6241 tatttggtat ggcactacat gtagaaaata tagataataa aattaaggag gtagtatgaa
     6301 ggaaagggct aaaaaaatat tagattttat tattaaaaat aacaatgtaa catcacaaga
     6361 actacaagaa aagtttaatg tttcaaagag aactatttat tacgatattc tagctataaa
     6421 taaacaacta ggaaaaagtg gtaatataaa aaatgtaaaa cacaaattta tatttgaagg
     6481 taatttatgt gatgcaagga aaataatttc aactgaagaa gataaatttt tagatagtga
     6541 ttacagaaaa acttttatat taaacaagat attacttggc gaaaaaatat caatagaaaa
     6601 actaacaaat gaaatgttac tttcaaaaaa cacagtagta caaacaataa ctgatgtaaa
     6661 aaaatacctt caaacaatgg gattaagatt agagtataag ggaaagtaca aaattatagg
     6721 tgatgaatac gttattagag agctgtttct gataattgtt caagaaaacg tactggaaat
     6781 taattctata agtgaggaag taagtagttt cgatacaaaa ggacatataa aacttactga
     6841 ttattcttta ttaaatctaa ctaagtttgt ggaatttcta aataaaagga taagagatgg
     6901 gaaaacatta tactcatata aatatctaaa tgaagctaaa aaaattagtt actttagtaa
     6961 ttgtaaagaa cttttatgtg aagaagctaa tgaaaatgaa caagcctata tatgcactta
     7021 cataagctca cttcccagct taaatagtga agttaaggaa gatgttgttg aagaatatgt
     7081 agataaactt atagataagt ttgaagtaaa tacagcaata aaattagaaa gtaagcatga
     7141 gtttaagaaa aatattttaa ggcacctcca ctcttcttac aacagaatac gatttaagtt
     7201 tcctattaga aatccaatgt tagatgagac taagtataaa catgagtcac tttataaaat
     7261 tataaaatca attatagaga atgaagaaga gtttcctgta tttgagggga taagagaaga
     7321 agaaatagga tttatagcag cgtattttgg aggatattta agagggtcta gggataatgg
     7381 tctaagaaga aataaagtct tactagtttg tcctaatggt cttatggtat caaagagttt
     7441 ggaaatacaa ctatataaat acataccaac catagaaata gtaggtatag tatccattaa
     7501 gcaactaaaa gaagtaaatg tatactacga ttacataatt acaactatag atatacaaaa
     7561 tgtaaacaac gtaattgttg taaatcctct tttaacatca tcagatgttc aattacttat
     7621 gaacaaacta ataagtgtaa aagaaaacga gaagtatttc aatcttgaat taataataca
     7681 agctataaga aaaaatggag ttatcaataa tgaagaagca ctaaaagctg atttattaaa
     7741 cataatacac aagatagatg aaggagagat gtatcaacca atgttaaagg aattaattaa
     7801 tgcagaaagg gtcaatataa taaaaaatgt tagagattgg aaagaagcaa taaaaatagc
     7861 ctcaaagcca ttgttagaag ataactctat agaagagtta tatatagaaa atatgataaa
     7921 gtcagttgag aaatatggac catatattgt tttagctgat agatttgctc taccacatgc
     7981 aagttctaaa gaaggagtaa acaagcttgc tatgtcttta ctaatagtag aagatgaagt
     8041 tgatttatta ggaaaaccag taaatatatt tatggtatta gctgctgtag ataacactac
     8101 tcacattaga gcattagcat cactatcaga gatgatgtac gaggaagaaa atgtaaaact
     8161 aataattaat ggtgataaaa gttcaatact agaacttata aataagcaaa attaggagga
     8221 atgaaaaatg aagatattag cagtatgtgg ttttggtgta ggttcatcaa tggtattaaa
     8281 aatgacaata caaaaggctc taaagcagtt aggtatagaa tgtgaagtag aaaatacaga
     8341 tataaattca gctagaggtg ctgattgtga ctgtatattc acaagtcaag aattgttaaa
     8401 tgaattaaaa ggaacttgta atgtagatgt atatccagtt aaaaagtaca tggatttagc
     8461 agaagtcaca gaagttgttc aaactttttt aagtgataaa aatgataaga aatagtataa
     8521 gttttaaaaa gtaaatttaa gttaatcaga ataaaataaa aacttactaa gttcaaaaat
     8581 agtaagaaag agaggaggga tttagtggta gaaaacttaa acagttgact tatcactaaa
     8641 aaatataatg cttgatttta tttcaaataa tattttacgt aatccatcta tgttaattgg
     8701 attaatagca gcatttggtc ttgtactaca gaagaagaaa gcatctgatg ttataaaggg
     8761 gtcactactt gcagctttcg gaattataat tatggagact ggaacaggta tgttagttag
     8821 ttcaatagca ccaattaatg gagctttcca aagtataagt ggtggtgcag taacaaaagg
     8881 tttaagtgat gttactttta ctgcaagtta tggtggaatt ataggtttag caatgtttgc
     8941 gggtttagct attcacctaa tgatagcaag atttactcct attaagacaa tcttcttaac
     9001 aggtcacatg ctttattggt tcccattcat atttgtagct tcaggagttg aagctggatt
     9061 aaatggtgga gtattaatag cttttgcagc agtattatca gcactctatt ggtcaataat
     9121 gccttggtta ttaagaaaat atgtgtttga tgttatagga gatgattctt ttacattagg
     9181 tcatccatct ggttgtttag cacttatatc aggatttgtt gctaaattag taggaaataa
     9241 agaaaaatct acagaagata taaacatacc tcaaagttta tcatttttta gagaaatatc
     9301 tataagtggt ggaatggcag tgtttttaat gtttatagtt gttgggatag taataccagg
     9361 tgcgtttaaa gatagtaatg agtttattgg aacgtatgca ataaagcaag gtctttcttt
     9421 tggagcaggt cttataataa tgcttcatgg ggtaagaatg ctaataaatc aaataatgcc
     9481 agcatttcaa ggtatatctg aaaaagttgt gccaaatgca ctacctgctt ttgactgtcc
     9541 aatattattt aattataaac caaatgctgt attaatagga ttcttagttg ctatgctaac
     9601 atctacagct atgattttaa tatgtaacta ctttaatgta tttaatttgc tacttatacc
     9661 acttgttata acttcattct ttgagtgtgg agcagcagca gtaataggag aatcacaagg
     9721 tggtatacgt ggagctataa taggtacagc tatagctgca atatttatgg tagttttagt
     9781 aggaatatct gctgtaattt actcaggaac tattcaaaat tggatactaa tatttggagg
     9841 taatgacctt tcattatttg gtataatcag taggtttata ggttcactat ttggaggaat
     9901 attatagata tgaaatttaa atacatagat gagataagaa gattaattga tataatagaa
     9961 aacgaagaaa aagtcaatat ggaaaaagca gtacaaatcc ttgttgaagc aatagaaagt
    10021 aaaaatgcta tattttcatt tggagcttca catgcaggaa tattaacaga agaattattc
    10081 tatagagcag gtggctgtgt tcttataaat ccagtatttg caaaatctct aatgttagat
    10141 acagcaccta taactcacac aagtaagatg gaaagattag aaggatatgg tacagctcta
    10201 gctgataaaa ctccaattaa aaaaggagat gtagttatag ttcattcagt atctggtaga
    10261 aatccagtaa gtatagagtt tgctatgaaa gctaaggaaa ataaggcaat agtaatatgt
    10321 ataactaatt taagttactc aaaaagtgta tcttcaagac attcttcagg aaaaaaactt
    10381 tatgaagtat gcgatttagt gatagataat catggtcaaa agggagatgc ctgtgtagag
    10441 atagatggat taaaccaaaa agttagtcca acttctactg taatagcaac tactgtgatg
    10501 aactctatta tagctcaagc tactcaggaa ttagttaata aagggctaaa gaatcctccg
    10561 attttctata gtgccaatat tgatggtgga gatgagttaa ataagaagat ttttgatgaa
    10621 tataaaagtg taattcatta tgaatattaa ggttaaaaaa atatgttaat gaactttgaa
    10681 gtttatcaa
//
LOCUS       DAEOTL010000115        10665 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEOTL010000115 DAEOTL010000000
VERSION     DAEOTL010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.117"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(206..2101)
                     /locus_tag="KRH82_003500"
     CDS             complement(206..2101)
                     /locus_tag="KRH82_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBG8656755.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKGGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGLSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(2728..2871)
                     /gene="scfA"
                     /locus_tag="KRH82_003501"
     CDS             complement(2728..2871)
                     /gene="scfA"
                     /locus_tag="KRH82_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBG8656756.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(2937..3299)
                     /locus_tag="KRH82_003502"
     CDS             complement(2937..3299)
                     /locus_tag="KRH82_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBG8656757.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEIGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(3357..3650)
                     /gene="yajC"
                     /locus_tag="KRH82_003503"
     CDS             complement(3357..3650)
                     /gene="yajC"
                     /locus_tag="KRH82_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBG8656758.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(3784..4905)
                     /gene="tgt"
                     /locus_tag="KRH82_003504"
     CDS             complement(3784..4905)
                     /gene="tgt"
                     /locus_tag="KRH82_003504"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBG8656759.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(4984..5469)
                     /locus_tag="KRH82_003505"
     CDS             complement(4984..5469)
                     /locus_tag="KRH82_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656760.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(5481..6506)
                     /gene="queA"
                     /locus_tag="KRH82_003506"
     CDS             complement(5481..6506)
                     /gene="queA"
                     /locus_tag="KRH82_003506"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBG8656761.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(6824..7843)
                     /gene="ruvB"
                     /locus_tag="KRH82_003507"
     CDS             complement(6824..7843)
                     /gene="ruvB"
                     /locus_tag="KRH82_003507"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBG8656762.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(7950..8552)
                     /gene="ruvA"
                     /locus_tag="KRH82_003508"
     CDS             complement(7950..8552)
                     /gene="ruvA"
                     /locus_tag="KRH82_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBG8656763.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(8545..9054)
                     /gene="ruvC"
                     /locus_tag="KRH82_003509"
     CDS             complement(8545..9054)
                     /gene="ruvC"
                     /locus_tag="KRH82_003509"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBG8656764.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKVIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            complement(9382..10011)
                     /locus_tag="KRH82_003510"
     CDS             complement(9382..10011)
                     /locus_tag="KRH82_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656765.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGTKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            10214..10537
                     /locus_tag="KRH82_003511"
     CDS             10214..10537
                     /locus_tag="KRH82_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBG8656766.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
BASE COUNT         3277 a         1941 c         1156 g         4291 t
ORIGIN      
        1 aatttttgca atatgaattt ctcaacatta taatcaaaaa ataaaataag gtatctcaat
       61 ctaattctaa atgagacacc ttatttttat tattttatct tgttatttgt atattttata
      121 atatctacac tatgtcttac atattaacgc attgtataat catatattat ctaaataaac
      181 ttttaatatt aattcctata tcttattagt tcttagtaaa taagtttatt ttttctgcta
      241 ttttttcaat agcgttttta gctattcctt cacctatttg tactaactta gtagcattct
      301 taagtcttaa ctcaactact tcttcttgtg atttagaaag ttcttctgta gttaatacta
      361 ttggagcctt tgaactagct gcaagtggtg ctgctgtaag tgcatcaact aattgtccat
      421 ttccacctac ataaccatct tttgctacat atgctttagt tgcacctgca tagtatttat
      481 tgattacttt agcattagta tcttttctat tttctccagc taatctttca actttattat
      541 ttaaatctat atcaactaat ttgtcttcaa cttcttttga tacagaattt tctccaccca
      601 ctatttctaa ttcttttcct tttaataatt tttcagcatt tgcatctaat tcgttacctg
      661 taactattat tggagcacca aattgagcag ctctagctga tatactcata gcatcagctt
      721 ctccatttcc acctactaca aaagcagtct taaatgtatc ttttaattgt tttgctattt
      781 ctaaagaagt ttcaaatcta tcttctccag aaactctctc aactttactt aaacctaatt
      841 tagaaagttt ttcttcagtt tcttttgata ctttagattc tccacctact atatatattt
      901 tcttagaaga tagattactt ccaagtactc ttaatatttc agcttctatt tctgatggta
      961 gtgaatcttt tttagataat aatattggtg catttttttg agaggcaagt ggtgctgatg
     1021 ctaatccatc aactatagca tcttctccaa ctaaaattat agcttctgct tctccatctt
     1081 tgaatctctc tttactaact tctactgctg ttgtaaatct tgaatcacca gataaaactt
     1141 ctacttttaa ttcttttcca ccttttacat cagttaatac tttgtgtaag tctctaacta
     1201 acttatggtt tttacttgaa acacttattg tttctggctt ttcatttgcc ttgcttaaaa
     1261 ctatatcaaa gcttgatttt tctggtttat ctttatcatc actatcttct tgttcttgag
     1321 taaggattgc ttcattttca aatgttaaag catatccatt tttaacttta ttaactattt
     1381 ctcttcctaa tgtagttaat ctaattccat caaataattc ttctgctgat atgtcttgta
     1441 aatctgcgtt tttaactgtt atcgtatgta attcttttga atctatgtca ctataactct
     1501 tttcataacc ttcaaaagta ccttcttctg atgttatcac ttttgagaaa tctaaatgtt
     1561 ggtctcctac atttaatgta ataacatttg ctgaatcttt tgctcttttt acttcaactg
     1621 tatttgtaga ttttatagtt gctgttaact tgttatcaga atcttctgct aaagttgcat
     1681 tgtaagcatt aactgcatct actatttctt gagcagtttt gtagttttca attttatagt
     1741 caactacttt tccacctaac acttgatgtc ctttatcttg aatagtaact tttaaacttt
     1801 gcccttctgt taaagagttt atcttatttt gtaattgagt tgcattagtt aagtttacat
     1861 tgtctacttt tatatcgtaa actctatcat ttacatttgc tcctgctttt gtatcttcaa
     1921 acttaacttc taatgctttt ctaacctctt cgattagttt agcagaatct ttcgcactta
     1981 ctgtgtaatt tttatcaaca ttttctgtca cagtattgtc tgcgaatatt ggtgctgctg
     2041 cactcataac tgtagcacct gccattacta ttgccatact tctctttttg ttgcttaaca
     2101 tatttatgtc ctccgaatat tattttttat tttttatatt cgtatttccc acacataaat
     2161 aatattatat ataatattat ttttcaatat attttatgtg tttacataat ttactaacac
     2221 aaacactaat aatatcttct tgaacccctt ccccctactt agctctctat aattatgctc
     2281 aaagatagaa atccctattt tatagtgatt ttctactaaa caatcatata ctaacaaaag
     2341 tattcaaact ccatttttat atactactat gcactaattt ttgctttact cttattactt
     2401 aaatatatat cactaaatta atatctatct ccatatatta aaatatataa catattataa
     2461 aaatcatcat aaattagagt ttaaaattaa aaattattct aatacatgta attgataaaa
     2521 aataaaatat aagagtagct actttaaaat aaatgttctt atatgattag atatttttgc
     2581 ataattaaac gataagaaat caaatttaat tttacataaa tagaatatat atttttatat
     2641 aataattgaa aataaaagag gatacctcat aatgataaaa gaatcacttt gagataccct
     2701 cttacaaaca actaaatcaa taattttcta tctttcacac tcttgatttg caactgtaca
     2761 agaagtttta caagctgatt gacaagaagt ttgacactct ccacatccac cttttgcagc
     2821 actttgcttt aaagtagctt gagataaagt ttttacatgt ttattttcca ttttcaacgc
     2881 ctccatttct aattgtttcc tattgattat atcataaaac tactttaata taaactctat
     2941 ttaaagttga cacccaatac gcctccaatg cctcctgctg ctgatattag caataactta
     3001 taaatcatcc ctatttcaaa tacaaacttt tcttgtgcta aaaacacagt caaaaaaata
     3061 catactatgt acaaaagtcc tactaaaagc ccatacataa gtcctttttc tttcatgtgt
     3121 tttgaagtgt aaaaccctcc tatagctgca gaaatagtag ttataaatga tgagaccata
     3181 gttatattat ctccaccaat atctgtaaat gtcaaaaata agttatacac taataaaaca
     3241 gccaaagtta ttatatatgc atatcctaga cctttaaaaa tataattaga ttttcccata
     3301 aaaaaacctc ctctcaaatt aatatatatt cgagaaaagg cttttaaatt actaatttag
     3361 tcttcttcta tttcttcttt tttagattta acagttccta tagcccattt ttcaaatgga
     3421 actttagttc tatttggtcc taattctaat attacaacat catcttcaac tttagctaca
     3481 ttagctacta ttccacctat tgtaatgacc ttgtctccta cacttaggct acttctcatt
     3541 tcttttaatt gtttgtcttt tttcttttga ggtctaatca ttaggaaata aaagattgcg
     3601 attactacta cccatagacc tatactcata attatttgtt gctgtggcat taatttttca
     3661 ctcctttgta aattatactc ttttgtaaat cataataaat gtttatataa caatttactt
     3721 tctctatctt tgagtactat tgaatattat atattaaaat gattataatt aatagtgcaa
     3781 aacctatatt tcatatccat attttgcaaa aaattcattt ctaaaatcaa gtaatctatc
     3841 ttccattatc gcttgtctta tttgtttcat taaatttaat aaaaagtgaa gattatgagt
     3901 agttattaat cttgcaccca gtatttcatt tgcttttata aggtgtctta tataagctct
     3961 tgaatagttt ttacaagcat aacaatcaca ttcagggtca agtggagtaa agtcttcagc
     4021 ataagttgca tttctaacta ctactttacc ttggctagtc attgcagttc catttctagc
     4081 gatacgagta ggtaggacac aatcaaacat gtctactcct cttataacac cttctactaa
     4141 gtcatctgga ctaccaactc ccattaggta tcttggttta tcctttggca taagtggagt
     4201 tgtatgctct aacacgtcat acataagtgg ttttggttct ccaacactaa gtccaccaat
     4261 agcatatcct ggtaaatcaa tattagttat ttctttcgct gattgttccc ttaagtcttt
     4321 atacatccca ccttgtatta taccaaataa agcttgcttg tcggtattat tatgggcatc
     4381 tttacatctt tttaaccatc ttgttgttct ttctaaagaa ttttttacat attctctatc
     4441 tgatgggtat ggtgcacact catcaaatgc catcattatg tctgaaccca atgcattttg
     4501 tatttccata gctttttctg gagttagaaa atgttttgaa ccatctaagt gtgacctaaa
     4561 ttctacacct tcttctttta tctttcttaa aggccctaga ctaaatacct ggaaccctcc
     4621 actatctgta agtattggtt tatcccaatt cataaactta tgaagaccac cagctctttt
     4681 tataagttca tgacctggtc tcatatataa atggtatgtg ttactaagta ttatttgtga
     4741 accaatctct tttaattctt ctggtgtcat agattttaca gttgcttgag ttccaactgg
     4801 catgaatatt ggtgtttcaa taatcccatg tggagtgtgt aatcttccta accttgcacc
     4861 actctgctta caagtcttta tcaattcgta tcttactgcg tacataaagt tctccttaat
     4921 catatttatt tctcattatt tcttaagata tatttgtaat aagctattca tataatttat
     4981 tgtctaaata gatttatctt cgtcttcttt gttctgttgt tccttaattg cttcttcatc
     5041 atgaatactc attatattaa gagcactctt gtcttttgtt actaaaaact tttttatagc
     5101 aaatagtcct gctatagcta taactcctat taaaacatct atcatacctt catttttagg
     5161 cagtagcaac atttttctag ctattgcgta aagtaatgcc tcaataaatg ctcctggtat
     5221 atgaagagat agcattacta caagttcaac acctattact aaaagtaata tttgtgctaa
     5281 aaaatcatta agctgactgt attgtactgg attttgaaaa tcaactatat atgctcccca
     5341 cataagtctt agaacatcta tagttcctaa aaatactgct attagaacta ctactgctaa
     5401 aacacgttca aatataaaag caatctttaa tatagggtta ttcttttttt gtttttgtaa
     5461 actatgcatc cattacctcc ctactttata atcatagcat ctccaaaact gaagaatcta
     5521 tatctttctt ttactgcctc attatatgca tttaaaacat tatcctttcc acaaatagca
     5581 cttactaaca ttattagtgt agactctggt aagtgaaaat tagtaataag tttatctaaa
     5641 actttaaatt tataacctgg atatataaat atttctgtcc atccactagt ttctttcatc
     5701 tttccatcct cattacaagc tgattctata gttctacaac tggtagtacc aacacatatt
     5761 acattttttc cattttcctt tgctctattt attttgtcag ctgcttcttg gctaaccata
     5821 taatattctg aatgcatctt gtgatttaaa acatcctcta cttttactgg tctaaaagtt
     5881 cctaaaccaa catgtagagt tacaaaggct atatctacac ctttttcttt tattttattt
     5941 aacaattctt ctgtaaaatg taatcctgct gtaggtgctg ctgctgaacc attatgcttt
     6001 gaataaacag tctggtatct ttctttttca tctagtctag cagtgatata tggaggtagt
     6061 ggcatatttc caagttcatc caatatttct tcaaaaattc catcataatg gaattttata
     6121 attcttgaac cttcatctga taaatctaca acttctccaa ttagctttcc atttccaaaa
     6181 gaaaatttag tccctacttt tgctcttttt cctggtttta ctaaagcctg ccaagtatct
     6241 tcctctgttc tttttaataa taaaaactct attttacctc cagtttcaag cttctctcct
     6301 attaatctag ctggtataac tctagtatta tttaatacta agcaatctcc tggatttaaa
     6361 tattctatta tatctctaaa tactttatgt tcaatattac ctgtctcttt atctaatacc
     6421 atcaatcttg agctagctct atcttctata ggaacttgag ctataagttc ctgtggtaag
     6481 tcaaatttaa aatcacttgt tttcaatgtt aaacttcctc tcttaaaatt tctccagcta
     6541 caataatatc aaaaaaacaa cttattttcc acaatattac cataatctat caagaaattg
     6601 ctatttttaa cagacaccat atccacaata tatagatatt tttccacgat atacatgtct
     6661 tatccacaat atatagatac aatacacaca atttttatcg tgtttatcca cagtatctac
     6721 agatataatt accattttgt ggatatgttt gaatttttag ccattttaga aatattttaa
     6781 tttaatgact cttttatttt ataaatactc gtataatcta tttttatttt tcattaggat
     6841 atggaatttt taagtgttca tatgctaatg gcatggctac tcttcctcta ggacctctat
     6901 ttataaatcc taattgaagc aaatatggct catatacatc ttctattgta tttctatctt
     6961 ctccgataga agctgccaat gtatctaaac ccactggtcc tcctctaaat ttttctatta
     7021 tagtcataag aagcttctca tctacaaaat cgagacccaa actatcgact cctaaaagtt
     7081 ccagagcatc ttttgccacc ttatcagtta tttttccatc agctctaact tgtgcaaaat
     7141 ctctaactct ttttagtaat ctatttgcta tccttggagt ccctcttgaa cgttttgcaa
     7201 gttctaatgc tccattagac tgtatctctg catctaagat gcttgaagac ctaagtacta
     7261 tttttgaaag ttcatcaact gtataatagt ccaatttaca aataacacca aatctatctc
     7321 taagtggatt tgtaagcata ccagctcttg tagtagctcc aataagtgta aatttaggaa
     7381 ggtcaagtct tatgcttcta gcagatggcc ctttcccaat tattatatct aggcaaaaat
     7441 cctccattgc tggatataaa acttcttcaa cacttctatt gattctatga atctcatcta
     7501 taaataaaac atcattttca tttaaattcg taagtatggc tgccaaatct ccagctcttt
     7561 ctattgcggg tcctgacgta attcttaaat ttacccccat ctcatttgct attatacttg
     7621 ctagtgtagt ttttccaaga cctggtggtc catataaaag cacatggtct aactgctcat
     7681 ttctcgattt agctgcttct ataaatatac taagttgttc tttggatttt tcttgaccca
     7741 aataatcttc taaagttttt ggtcttaaac tgttttctat atctatatct tccatcttca
     7801 ttgtagaagt tattatccta ttttcatctt caaaaccttg catttatacc cctcctctca
     7861 tacttttgaa aatctacttt atatattttc aaatttacat aaactcctta aatattgttt
     7921 taaaatccaa atattataaa atccaaatac tatttcaaag atttactcat tatatatgta
     7981 agtgctttct ttataatagc ttctgtattc ataccatctt ttttacattt ttgaactgcc
     8041 tcttttgatt ccgacaaagt atagcctaaa gctacaagtg catctacaga ctcatcttgt
     8101 gatatcaagg taggtttttg tgataataac gttggttcaa actctatgtt atttttgtct
     8161 accttatcct taagctctaa gacgattctt tctgctgtct ttttaccaac accaggagct
     8221 ttggataatt ttccaatgtc ttcacttaaa atatatgctc ctaactgtgc tggtgatgca
     8281 aatgatagta ttgaaagcgc caccttaggt cctattttag atacagatgt tagtaattca
     8341 aacatcttaa gttcttccct acttacaaaa ccacaaagac tcatatcatc ttctcttaca
     8401 attaatttag tatatatttt tgtggcttct cccacttgta aattcattat tgtattggat
     8461 gatacattta ttttatatcc tatcccatta ttttcaacaa ctatactgtc tatataaatt
     8521 tcttctactg taccttttat ataactatac atacttacca cctatattct ttagagtttt
     8581 ttcaagtttg tttgaatgag catggcaaat agccacagct aaagcatctg caacatcatc
     8641 tggttttgga acttttttta gacttaaaaa tgaagttacc atctgttgaa cttgtgcctt
     8701 atctgctctc ccatatccaa ctacaccttg ttttacttga agtggagtgt attcatatac
     8761 aggcttccca ttatgagcac atgcaagcat agtaacacct ctagcttgtg caactgttat
     8821 agctgttttt acattcttgt taaagaataa ttcttccatt ccaacttcat ctatattgta
     8881 attctttact attgtatcaa ttcctttata cacaagttcc aatcttctcg atatattcat
     8941 atgggcaggt gttgtaactg ctccataatc gattacttta aacttgctat ttttgtattc
     9001 aattatacca tatccaacta tggctatacc tgggtcaatc cccaatatta tcatttttta
     9061 aaattccccc taaaaataaa agaaatacca aaatgtattt ctcataaaaa cttatgttct
     9121 aaatcattat atcataaata atattaacaa atcataaaat gctctatgta aaatataaaa
     9181 tcaaataaaa aagttatatc aaagcaagat tttacctcaa tataactttt atatttatta
     9241 caaataaatt attgtatttt tataggaatt aaatgtgact acaattttaa tactaatcta
     9301 tttaatatta aattatttat tattaattta cttagtattt aacttactta gtatttaact
     9361 taaaataata ttaatttact attaacttgc aaagtcttct aatcttgaat aggcctcttc
     9421 ttcagtatcc ataactacac cttttttgat ttcatcttga actgttttag gaagtgaatc
     9481 tactcttatt tttgtttttt ctactaatgt tttagttcca ctatcatcat atttatatag
     9541 tgctatattt ccattatcat tttcaatagt atatttacct tttatagtaa catccattgc
     9601 ttgtacatct ttattatcac tatatttaga ttctaccaat atgatttcat ttttatccat
     9661 actctttatt tttttagttg gatattcttt tttaaaatat gatactattt ctgacttcgt
     9721 cttatctaat aatgactctg gaactattcc tgccattgta agtgttctct tatagttagt
     9781 ttcattttcg ccttcacttt gaagccaaac ttcacaattt ttatttaatc caaaagcttc
     9841 ttttgacttt tcattcatat tcgcactagt acttacaact tcaccagttt gaactccatt
     9901 gtgttttaat cttgtcccta tataaactcc gctacttaat acaaatactc caaccagtat
     9961 taaggcagat attttccaag gaaataattc ttttttcttc ttttcaaaca ttgattacgc
    10021 ctcctttttc tattattttc tccaagctgt aagtttttat acaatttagg taaattttag
    10081 aagaaaatat atttatattt caaattactc taagaataga tattttctaa aaggtagttt
    10141 tctcttaatg gttatattct tgtaattata tggacataat ttataataaa taatcgttta
    10201 ggaggtaata actttggaaa gaataaactg taatgtaatt aactgttcac ataacaacag
    10261 ccatatatgt tatgcagata aaatttttat aaatggtgaa aaagctcaca atgatagaca
    10321 tacttgttgt agttcatttt tagatgaatc tatttatagt aatttatcta gcaacgttaa
    10381 taatagaaat tgtgaggaat tagtttgtac tgtaaaaaat tgtaaataca acaaagatgg
    10441 tagcttatgt acacttgata atatattggt tgctcctgaa actgatagag taaatcttta
    10501 tattgaaaca tgttgctcta gcttcgaatg taaatagtca tagtataaat ataagggtgt
    10561 caaatgtaat taaactaaca tagtgtagag tatctacaac tattagtttg attatacttg
    10621 acacccttat ttattttaaa taaaatttca ttattataac catgt
//
LOCUS       DAEOTL010000116        10430 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEOTL010000116 DAEOTL010000000
VERSION     DAEOTL010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10430
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.118"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            24..422
                     /locus_tag="KRH82_003512"
                     /pseudo
     CDS             24..422
                     /locus_tag="KRH82_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            410..1348
                     /locus_tag="KRH82_003513"
     CDS             410..1348
                     /locus_tag="KRH82_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBG8656767.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFRLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1732..1956)
                     /gene="secG"
                     /locus_tag="KRH82_003514"
     CDS             complement(1732..1956)
                     /gene="secG"
                     /locus_tag="KRH82_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBG8656768.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2561..3853)
                     /gene="eno"
                     /locus_tag="KRH82_003515"
     CDS             complement(2561..3853)
                     /gene="eno"
                     /locus_tag="KRH82_003515"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBG8656769.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            complement(4441..5973)
                     /locus_tag="KRH82_003516"
     CDS             complement(4441..5973)
                     /locus_tag="KRH82_003516"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBG8656770.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQVSMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
     gene            complement(5982..6725)
                     /locus_tag="KRH82_003517"
     CDS             complement(5982..6725)
                     /locus_tag="KRH82_003517"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBG8656771.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            complement(6751..7953)
                     /locus_tag="KRH82_003518"
     CDS             complement(6751..7953)
                     /locus_tag="KRH82_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBG8656772.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            complement(8175..9182)
                     /gene="gap"
                     /locus_tag="KRH82_003519"
     CDS             complement(8175..9182)
                     /gene="gap"
                     /locus_tag="KRH82_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBG8656773.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            complement(9242..10264)
                     /locus_tag="KRH82_003520"
     CDS             complement(9242..10264)
                     /locus_tag="KRH82_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8656774.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
BASE COUNT         3219 a         1915 c         1191 g         4105 t
ORIGIN      
        1 atataaaatc ttaaggagtt gccatgataa aaaaaataga gcatgtggtc attactaata
       61 ataatataga aaattatatc aatttttata aaaaatttgg tttttcatct aaagaaatga
      121 gcaaaaatta taaacttaat gctagaaatg ttaagataaa tcttaacata aaaggttata
      181 aatttttacc ttatgttaaa aattcaaaag caagtagaga taacttatgt tttaaaataa
      241 acacaaatat tgatgagcca aaaaaatact tagaacaaaa tgagattcaa attaagtgag
      301 gaattgtaga atgtacaggt gtctttggta atatgaaatc tatttatttg aaaaaaacta
      361 atggaaattt aattgaatta tcaaatcata gaatcacgga gagtaaacct tggaaaattt
      421 aatcctatca ataaatgttg ttcttccttt gtttctcaca atgtcacttg gatatgttct
      481 aaaaaaatta ggtctatttg atactcatac tttaaataaa atgaataatg tctgcttcaa
      541 gtctttcttg ccattattat tattttttaa tatatacaat acagatttag atggttctct
      601 taattttagg cttatggctg tagctgttat aattattttt tcaatcttct taatcttagt
      661 ctttattatt cctaaaattg aaaaagataa taagacaagg ggtgcattaa tacaaggtgt
      721 atttcgtagc aatttcgtta tatttggtat tcctgtgaca atttcactat ttggcgataa
      781 gagtattgga gtcacatctt tattaattgc agttattgta cctatgttta atgtattatc
      841 tgttgtaatt cttgaaattt ttagaggtgg caaagtaaat ataaaacata tgattaaaag
      901 cgtcttaaca aatccactca taatcgcctc ttttatagga ttgacaatgc taattttaaa
      961 tattaatata cctacatttt tacacaaaac tattggtgat atttctaaaa tagctactcc
     1021 tttatcactt ataattctag gtggctcttt tagtttttct gctataaagg ggcatataaa
     1081 ccccattata ttgggcgtat gtggaaaact tatacttgta cctgctatat ttttaccaat
     1141 tagcattttt cttggattta gaaatgtaga attagcttca cttatgataa tgttatctgc
     1201 tccaactgca gtttcttcat ttacaatggc acaacagatg gattctgaca gtgaattagc
     1261 tggacaaatt gtagtattta cttctggatt ttctataatt acagtatttt taataatatt
     1321 tattttaaag cagaataatc ttatttaatg atatttgata acacaaattg gtattatgag
     1381 aaacatatat aaaatcgatt taattgcgta aaaacatatt attatactat ttttactata
     1441 taatataact ttgtgtatat tatctcatta aacatggtga aagtagtgtt gctatatatt
     1501 ttttagtttg aaaaaaatat ataaatacaa acaatatata aatacaaata ataaacgcca
     1561 acaaatagtc aatctataaa ataaaaactg gactaatcat ataaaatcat tagtccagct
     1621 tttattttac gtacttttta tgttgatgta cttttattaa aaactaaatt taatttttaa
     1681 atgtctagca aatgcactaa ttaaataatg gccagttatt caacaatatc actacttctt
     1741 aactataagt aatgccaatg catttataaa aaataatact gctgttatct ttgtaactct
     1801 agcaagaaat gcttgttttc cttttggttt aaagtaagct tgacttcctt ctccaccaaa
     1861 ttctgaaggt aaagcattct tagaatcttg aggcattatg ctaattacta gtaaaatccc
     1921 tagtactact tgcacaccca ttaaaatgtt gctcattctt gcccctccta tctgtttatt
     1981 acttaaattt cattactctt tagtgtatca caataatata gccatttcaa gactattatg
     2041 ctataaataa catacaaaaa aatatattgt tactataata tattactata ttctcaatat
     2101 aaaaatgaat aaaacttaga agagaaaact atttaaatta atacataaat taatgcataa
     2161 attaacactt aaaataatct actctcattg catatattat aaatagccac caaaataaaa
     2221 caatcatttt aaaatattga tataactttt aatttcaaca taatttaaaa taaataatcc
     2281 acatttagca ataatacttt aatgacaatt atgattaaat caaaatatgt cttcactttt
     2341 attttttaat aaaaacctcc tatgcaatta gataaaaatg agatagaaac atttattcat
     2401 attttttctg aatctatgaa taaaattaag taataaaata taaaaaagga taagtgaatt
     2461 gaaaaatcaa ttaacactta tctcttttat atcttataag atgagcttaa atatcttata
     2521 ttctctcttc attaatcttt tttagtaacc attttaataa ctattttttt aagttataga
     2581 aagattttaa tccacaatat ctagcttgct ctccaaccat ttcttctatt cttaataatt
     2641 ggttgtactt agcaactcta tcagttcttg atggagcacc agtttttatt tgaccagcat
     2701 ttactgcaac agctaaatct gctatagtag aatcttcagt ttctcctgat ctgtgagata
     2761 taacagcagt atatcctgct ctcttagcca tttctatagc atctaaagtt tcagttattg
     2821 tacctatttg attaacttta actaatatag agttagctac tccattttca attccttttt
     2881 ctaatctctc tgtgttagta acaaataagt cgtcaccaac taattgtaat ttatttccta
     2941 atttttcagt taataatttc catccatccc aatcttcttc gtctaaacca tcttctatag
     3001 ttattattgg gaagttgttt gaccaatctt catataaagc aaccatttca gcagccgtta
     3061 actcttttcc ttctcctgct aaaacgtatt ttttagtttc tttgttgtac atttctgtag
     3121 cagcaacgtc aagacctaac ataacgtctt cacctggctt atatccagct tttgttatag
     3181 cttcaactat taattctaaa gcttctctgt ttgaacctaa gtttggagca aatccacctt
     3241 cgtcacctac accacaagct aatccttttt ctcctaaaac tttctttaat gaatggaata
     3301 cttctgctcc cattcttaaa ccttctttga aacaacaagc tcctactggt aatatcataa
     3361 attcttgaac atcaacgttg ttatcagcat gctctccacc gtttaatatg ttcatcattg
     3421 gaacaggtaa ttgtttagca tttactccac ctaagtattg gaataatggt aaacctattt
     3481 catcagcagc tgctctagct actgccattg aaacacctaa tatagcatta gctcctaatt
     3541 tacctttgtt tggagttcca tctaattcta tcatgattgc atctatagct ggttggtcaa
     3601 atgcatccat tccttctatt tcaggtgcta ttatttcatt tacgttagca acagctgttt
     3661 ctacaccttt tcctaagtat cttcccttat ctccatctct taattcaaca gcttcaaaag
     3721 ctcctgtaga tgctcctgat ggaactattg ctcttcccat tgctccatct tctaatacta
     3781 cttcaacttc tacagttgga tttcctcttg agtctaatac ttctctagca tatactaatt
     3841 caataactga catttgtata tctcccttcg attttctatt agttaaattt tcatttactg
     3901 taaacatccg tctactattt taatctactt tctatattat agtacataaa gttgcttttg
     3961 aaaattaggt acaaatttat ttgatgggta aatttgtaaa agttcctatt tttattttat
     4021 tttttataat attttaattt atataatata aaaaaacttg tctaaaatcc aaaaccaatc
     4081 ttaaatacac aaatattata actagattta aaacattaaa cataaaatgt acaactaatg
     4141 attctaaaat ttttgcttat ataatatata ttaattatta ttatttatat tgttattgtc
     4201 tatcttgtta ttatttatat cattatttac attattatct atattgtaat tttttatttt
     4261 ataaattgtc tatcttgtaa attttataaa acatatcttc atctacacct tacaatatcc
     4321 agaacttaca aaatttaaat cttatgtcat aaagtctaaa ctttacaaaa taaacctaaa
     4381 ctgcattatt tttaaattta tattgtagtt tatatattat tctctactta tcaaaatcga
     4441 ctattttgaa ataagtgaat gaccagtcat ttcttctggc ttttctaact tcatcatatc
     4501 taaaacagtc ggtgctatat cagataatct tcctccatcc aataattttg cactttcata
     4561 ttcttgacca actacaataa atggtactgg attaatagag tgagccgtta cagtttttcc
     4621 tgtttctggg tctaacatat attcagcatt tccgtggtca gcagttatta ttgcacttcc
     4681 acctaactct actattttat ctatcaattt tcctacacaa gtatctacag tttcaacagc
     4741 ctttatagcc gcttctatac ttcctgtatg acctaccata tcaggatttg caaagtttaa
     4801 tactataaag tcaaacttat cttctcctag tttatctaaa gctttatctg tcaattcata
     4861 tgctgacatt tctggtttta aatcataagt tgcaaccttt ggagaaggta tcaatagtct
     4921 ttcttcacct ttatttggct cttctactcc accattgaag aagaaagtta catgtgcata
     4981 cttttcagtt tcagcagctc taagttgagt ttttccattt ttagctagat actcacctag
     5041 agtgttggct aaagattgag gtccaaatgc tatatgcaca ttctctatag ttatatcgta
     5101 ctctgttaag catacaaaga agtttttaat atcttctctt ttaaatccat caaactcttc
     5161 acaaactaaa gctctagtta tttgtctagc tctatctggt ctaaagttga agaatataat
     5221 tgaatcattt tcctttatac ttccaactgg tttatcatct ttcataataa ctgttggcat
     5281 tataaactca tcattttttc catcatcata agagttttga atagcttcct caatagaatt
     5341 tgctttttca ccaatacctc taaccatggc attgtatgca agttctactc tttcccatct
     5401 cttatctcta tccatagcgt agtatctacc agaaactgta gcaaattcac ctactccaat
     5461 ttcatccata ctaacttgta cttctttggc atattctaat gcactttgag ggtcagtatc
     5521 tctaccatca gtaaatgcgt gaacatacac cttttgtacg cctttatctt ttgccatttt
     5581 gattatagcc ttaagatggt ctatatgtga atgtactcct ccatcagaca aaagtcccat
     5641 tacatgaaga gagttttctt ttgcattatc cattgcttca cataaaactt tattagtaaa
     5701 aaagtcacca tcttttatag attttgttat tctagttaaa tcttgatata ctattctacc
     5761 tgcacctatg ttagtgtgtc caacttctga atttcccatt tgaccatcag gtagaccaac
     5821 atcaagacca ctagcattta tcaatgtgtt tggatactct ttttttattc tatctaaatt
     5881 aggagttttg gactcagcaa ttgcatttcc cttaacatcc ttattgtatc caaacccgtc
     5941 cataataatt aaagcaactg gttttttcat catttcactc cttagaaatt aacaaggtct
     6001 aggtaatcat tactagctaa actagctcca cctactaaag ctccatctat atcactttga
     6061 cccattattt cggctacatt tgaaggttta acacttccac cgtattgtat tctaacttca
     6121 ttagctaatt ctccatataa tccttttata acttctctta tataagatat aacgtcatta
     6181 gcatcttcag cagttgcagt tttaccagtt ccaatagccc agattggctc atatgcaaca
     6241 actacttttg ctaaatcatc tttaagaaca ttttctaaag ctttttcaac ttgaacttta
     6301 caaacatctt tagtttttcc agcttctctt tgttctaaag tttctccaac acataatatt
     6361 gggtctattc ctacttctaa tgcttttaaa actttcttgt ttacagtttc atcagtttca
     6421 ttgaagtatt gtcttctttc tgaatgtcct attacaacat agtccatatc tatttctttt
     6481 aacataagag gtgaaacttc tcctgtaaat gctccttttt cttcaaagtg catattttga
     6541 gcacctatct ttatatttgt acccttagta gcttctttta aatcctttaa taaagtaaat
     6601 ggtgcacata taacagcttc tactttatca gaatttactt tatctttaac ttcatttaca
     6661 aattctaaag cttcttttat tgttttatgc attttccagt ttcctgcaat tataggtttt
     6721 ctcattttac aatctcctct atatattagt ttatttatta tctaatgctg caatacctgg
     6781 taattcttta ccttctaaaa attctaatga tgctcctcca cctgttgata cgtgagtcat
     6841 cttgtcacca aatcctaatt gattaactgc tgctgcacta tctccaccgc caattacagt
     6901 agttgcatca gtcaactctg ccatagctct agctactgat aatgtaccat ttgcaaagtt
     6961 ttcaaattca aatactccca ttggcccatt ccatactaca gtttttgatt cttttatagt
     7021 ttttacaaag tttgctatag tcttaggtcc catatctagt cccatgtaat cttcttttac
     7081 attagcatct tctgttacta ttggagtagc atctggtgca aagtggtctg ccataacaac
     7141 gtctactggt aataataagt taacaccctt attcttagct ttttccatca tttctttagc
     7201 atattcaact ttatctattt caagtaaaga agttcctact tcataaccct gagcttttaa
     7261 gaatgtataa gccattcctc cacctattat tagattatca actttttcta ataattcgtt
     7321 tataacagct aatttatcag aaactttagc tcctccaagt atagctgtaa atggtcttac
     7381 agggtttgca acagcttctc ctaagaattt taattctttt tgaattaagt atccacaaac
     7441 tctctcttgt aaaaactcgc ctgcaccaac tgttgagcaa tgtgctctat gagcagttcc
     7501 aaatgcatca tttacaaata tttcagcaag tgatgctagt tctttagaga aattctcttc
     7561 gtttttagtt tcttcttttc tatatctagt attttctaat aatactacat ctccgttttc
     7621 cattttttca gttgctttct ttgcattttc tcctacaaca ttatcgtctg ctgcaaatac
     7681 aacttctttt cctaacatct cagataatct ctttgctact ggtgctaaag ataattctgg
     7741 tttagcttct ccttttggct ttcctaagtg agagcataat ataacttttg cccctttaga
     7801 aattaaatat tgaatagttg gtaaagctcc gttcaatcta ttttcatcag taattacacc
     7861 atcttgtaat ggcacattaa agtcacatct tactaatact ttttttccgc acacatcaat
     7921 atcttctata gtttttttgt taagcattga cataaatatc tctcctttta ataaagtaat
     7981 tttttattgc caagtataat atagtacata cttttaccct attaaatata tcatattatc
     8041 atatttttat atatagtatg taacattatt taggtgtatt ttatatattt tttcttaaaa
     8101 aaagtcctga gtccgtagta ttaaactaca aactcggact ttgtcaatct acttttctat
     8161 tttctcaaaa ctgactattt tgctaattgt gcaaagtatc ctaaagttct tattaattga
     8221 gaagtataag acatttcatt atcataccaa gaaacaactt taactaattg ttttccatct
     8281 acttccataa cttttgtttg agtagcgtca aataatgaac cgtagcttat tccgattatg
     8341 tcagaagata ctaacatttc ttcagtatat ccgaaagatt cgtttgaagc ttctttcata
     8401 gctgcattta tttcttcaac tgtaacattt tttcctaatg tacaaactaa ttcagttatt
     8461 gaaccagtta caactggtac tctttgtgct gccccatcta attttccttt taatgaaggt
     8521 attactaagc ctattgcttt tgcagctcct gtagtgtttg gaactatgtt tccagcagca
     8581 gctctagctc ttcttaaatc accttttgga tgaggaccat ctaaagtatt ttggtcatta
     8641 gtgtatgcat gtatagtagt cattaatcct ttttctatac cgtatttatc atttaatact
     8701 ttagccattg gagctaaaca gttagtagta caagaagctc ctgatataac tgtttcagaa
     8761 ccatctaata tgtcactgtt tgtgttgaat actattgttt ttaaatctcc agtagctggt
     8821 gcagatataa caactttctt agcccctgct tgtatatgag cttcagcttt atctttagat
     8881 gtaaagaatc ctgtacattc taatactata tctactccta attcagccca tggtaggtca
     8941 gcaggatttc tttctgctgt tacttttatt tcttttccgt ttactacaaa agcaccttct
     9001 ttaacttcta tttctccgtt aaatcttcct tgagctgtat catatttaaa taaatgagct
     9061 aacattttag cgtctgttaa gtcgtttatt gcaacaactt cgaacttatc ttgttgctcc
     9121 atcatttttc ttaatgctaa tcttcctatt cttccaaatc catttatagc tactttaacc
     9181 attttcgcta cctcctataa agtaaatgta tgttttctag ctctgtgcta ggtcttgact
     9241 tttataataa tgacaatatc ttataagcac tttcttcatc tgttacaaga accatgtttt
     9301 tatgcatatt tgatatagct aataaggctt ctactttttc agtccctgca aagattgcaa
     9361 tagtttcttt tacttgttta actgtttcta aatcaattcc aacagtgttc agtttgtaaa
     9421 ctatttctcc atctttgttg aaataatatc caaatgcttc tccaactgca tttttagata
     9481 atatctcatc aaccttgtct tctggaagtt ttcttctctt tgccatgaca tctgctctac
     9541 ctatactaaa aactaaaatg tctgttcttt taatatactc caaagttgtc ttaatctctg
     9601 gcacttggct aagagttttc attgcacttt catccaactc atctggtata tgtaaaagtt
     9661 tgcaattaga atgtaatttc ttacttattg aagcaactat attgttagat tgcatctcta
     9721 catcagttcc catacttcct ctagctggaa ctattgtaga gtttggatat ctcttatcag
     9781 ttttaataac gtttgaaaac tccaacatag tgcttcctcc tgttattgaa acgatatctc
     9841 catcttttaa aatgcctaag aaatattcgc atccatatct agttacatct tttagtaaac
     9901 ttccattttc atcacagctt ccaggaacta atattaccct ttttattcca agcttttctc
     9961 tgactctatc ttgtaactta gacaatccca tgatgtcact catgatgtcc ttaagtttat
    10021 ctaacaaatc agaaccttct ttagtgatag tcatcccaga tacagctacg tctataagtc
    10081 cttgttcttt taaaaactca gtttctgacc tgattattct ttcactaatc tctaatacat
    10141 ttgataatgt tctcctacct attggttcac ttaaagatat ttgtcttaaa atagagtatc
    10201 ttctttccat aagttcaatt gcctgtggaa tcaatttctt ttgaatttct aataagttct
    10261 tcataacata ctccttattg ctttcctttc gggacttttt ttgtccctag tgtttattta
    10321 agtcccacaa gatattttta ttttatagga tttgcgtata gatttcaata gtttttcaaa
    10381 aactttttta tttttttatt ttataaaata tttctccacc attttcaaat
//
LOCUS       DAEOTL010000117        10122 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEOTL010000117 DAEOTL010000000
VERSION     DAEOTL010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10122
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.119"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(97..1977)
                     /locus_tag="KRH82_003521"
     CDS             complement(97..1977)
                     /locus_tag="KRH82_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBG8656775.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISIKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTLDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGADRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(2187..8150)
                     /locus_tag="KRH82_003522"
     CDS             complement(2187..8150)
                     /locus_tag="KRH82_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBG8656776.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNIQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEANSNTNQDKNNDKENSSMDKPNSDEDTPKEGDNISKDDNFTTSTYSRSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKISFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPINN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIMVDMKETLPIVGLKYTKPEAEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADETRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(8274..8359)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(8531..9934)
                     /locus_tag="KRH82_003523"
     CDS             complement(8531..9934)
                     /locus_tag="KRH82_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBG8656777.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
BASE COUNT         2771 a         1876 c         1159 g         4316 t
ORIGIN      
        1 ttattagatt gttaagataa tgaaaataaa ataagaatgc atttaaatat ataactttat
       61 atctaaatac attcttattt tctatttact taatatttat ttttcaatta aactcttaat
      121 cttgtctatt acagatgagg ctattcctcc acctacttca aacaactttg atgaattttt
      181 accttttaat gacgattctt gtgatttatc taacgtattt gtagcaagta taactggtga
      241 attgttttta gctgctaatg gtccaactgc taaagcatct ataagtttat cttgatttgc
      301 aactacaact ccatctagct tagattgaga gtagaattta tctattactt tggcattcgt
      361 ctcttgtcta gtttgacctg ccaccctatt gtttgatata tctttgtttg ctatttttcc
      421 aacttgttca atagccttgt tagatatttt ttctactcca ccaataaaat atatatttga
      481 caccttattt gatttaataa attgttcagc ttcattatct acaccatctt tttgtgtaag
      541 tactattgga gttttttctt taccagccag tgatgctatt gataatgaat cagcttctcc
      601 atttcctgct cctatataca acttgcttac attattcgtc ttatctattt cttttgctat
      661 attaatagaa gtttgatatc ttgtatctcc acctattctt tgtactgata tttttgaatt
      721 tacagctttg atagcttcaa caactgaatt tggcattgag ttgtttccac ctatcacaat
      781 tacttttgat ggatttagcc ttttcaattc ttctacagtt ttttgaggaa gcttttcatt
      841 tgatgataaa agaattggtg agttttttac actagcaagt ggtgtagctg taagcccatc
      901 caccatactt ttatcttctc catttactat tacaactgta tctgattttg tccaaccact
      961 ttgagatatt ttgatagctg tctcaaatct atcagcacct tttaattttt tgactgtgac
     1021 attagatgta gaatcacttg aatttcctcc tccagagctt ccaccactag atgagccgcc
     1081 tgaattactt cctccgccat tatttccacc attgccatta tctggtggta attcatccgg
     1141 ttttgataat tcattttcaa ctatgtattc taaacttttt ggaagtgtaa cttcaacata
     1201 tttgtttatt gtagcttttc ttcccttagt tgttttttgt gctaatccaa gttttaatat
     1261 tacatttgaa ccactttctt gtgtttcttt actaacaata gaatagttta tcctaatatt
     1321 gtttaataaa tattcaagtg cttcactttt ctctacctta tacttttcag ggtcgttttt
     1381 actagaacca gttccaccaa tcggttttac ttcactctca ttaataaggg taaatattaa
     1441 tccttcatca gagcttatat tttcataatc caatgttttg ttgttatatg ttacaatttt
     1501 taaagctggt ttatcgcttg ttccttttcc taaaacttta tagtcagcat ttgagttact
     1561 gccagatttt tttatagata ttcttcctat attcaatcta tttccgtcta gtaaatcttc
     1621 atttgatgta acatatatat ctaatgtagt tgtattactt gatttgttgt attctgctct
     1681 acaagtagca tttgcatttc cactttttat ctgagatttt atattatcag accaagtaat
     1741 cttttctttc tgctcattat ctactacttc aacctcacct tgtactttta tactggcttg
     1801 aaatgaatat actatgtttt ctactgagtc cacagatata tctatagtat ttactttctc
     1861 atacgttttt gttccttgta aaactggagc tgcatatgca catgtagcac taccagttac
     1921 agctactgcc atagttgata ctgctatagt tcttataaaa gattttcttt tactcattaa
     1981 cacccgtcct tatctatcat taactaagtg gataaattta cttatccacc tagcttttat
     2041 atttaattta taaattaccc taaacttata gttacattta tatactttac ttttaatatc
     2101 tactatttta aaactattct agtacctaat cttattagat atacaatgtt agtgttagta
     2161 tttttacgtt tttagagttc cacctactat ttatctctaa caatattacc ctttacttta
     2221 ttgcttacag ttataacctt cttattactg atatcaatag aatttcttgt agcttttcta
     2281 gctttactat tactatcagt aagacttatt gtctttaact catcataatt cttagctcct
     2341 acaggtacat acattgtatc acttacaaat ctttgaccta ctggagtatc tccttgaagg
     2401 tcattgtatc tatatagttc agccttaacc ttatcactta aagaatcaaa gttttctttt
     2461 ggcatatagt aaacccatgt acctttactg atttcaccta gttcaccttt ttctggaact
     2521 tctgcaaata aaagcgcttc tccagatata gtcttattgt ttttatctat aagtagtggt
     2581 aaattaaatg ctggatttcc actgtattca cctgtaataa ctattgaacc cgctggaatc
     2641 ttacctgttt catcttcact tgtgctagag tcatcacttt gatatacata atcttctgct
     2701 aattttccaa ttccattagt acgagtttcg tctgcattat tcattgtgcc aatttctata
     2761 ttatcacctg gaggtcctat tatatctaat tctgcaactt ctatattaga cttattattt
     2821 gagattagtt ttacatatct agcttggtat gtccaaagtt taccatcttt attaaatgta
     2881 actctagctt cattatcttg gtcttttcct ccaccaacta aatcttgtcc atattcaaaa
     2941 gttccttgac ttacatcttc ccagttcttt ttatcattac ttacttgtat tttgtaatta
     3001 gttaaaggat tgtatgttgt gctagtattt tttctaaagt taaataatcc ttttaatgag
     3061 aacttcctag cttctgcctc tggttttgta tattttagtc ctactatagg taatgtttct
     3121 ttcatgtcta ccattatata tggattttct tctacattta tatcagggtc tttttgaggg
     3181 tctttgttcc actctgcttt acttattatc tttcctttat atgtagtact tgcatcatta
     3241 tcttttatat tatcaatttc aggattttgt aatggtccat gtgagtcatt ttcagttcta
     3301 acatcaccgt cagaaacagt atttgttatg aatgaccatg ctgatttatt tattttccct
     3361 tcatctgata attttacagt accaacttca aattcttctg ttggatttag gtgataatca
     3421 tatgcaacta ccttatatgt aaatgctctg ttattaagag gagatatatt atcagtaaat
     3481 ttagtcttac tatttccttt tgcatccaca aatccaactg ttctgtattt tacctgtgtt
     3541 ccattttcac catctaaata atttccatca cttcttatta tttcgtatcc tagtatctta
     3601 tctttatcct tatctacatc taggtctata gatattttat tagatttaac tagagaacca
     3661 ctttgtattc catcagaaaa actagcactt actttagtat cttttgccat actagctata
     3721 ttttcattta aaatctttct tctagcttcg tcatttacat attgtatctt tcttgattct
     3781 ttttcgtagt tcttactatc cattatactg tttaattctg gtgtaatttc tactccccat
     3841 gccttaaagt aatctcttaa atctttttca acaacacttg atgccattgc tactagcatt
     3901 tggtcttttg gtaaactatt aattgggtca ctacttgaaa gtgctctgta ttttcttgaa
     3961 atctttgcat agaatgtatc attacttaaa tcagcatctg agttattctt taacattgaa
     4021 cccgtaaaat catcatcata agctagatgt aattgccata acattccaag cctttcaaat
     4081 acattgcttg gtatacctaa gctatttgaa gttacatgct catatatctt atccattgtt
     4141 gaaccttcaa gtcttgaatg tgtcttatca tcaaaggtct gagcaagtaa agcaagtaca
     4201 ttgttactag tttcgctata tgtcatcttt ccaatatctg taacatgtcc tatctcatga
     4261 cctattcccc atccaaataa gtttcctcct gtagcttttc cactatcatc tatttggaaa
     4321 ggtactccat tcataagccc tggaactgaa ccatattcta ctcctacatg taatccagaa
     4381 gcatacataa atgctccaat aaacattctt tggtatttta tgttcatacg agattttgga
     4441 gccatatcat ttttagttaa gttaaattca ttatcatcta cagttccatt accatctaaa
     4501 tcttgtgttt taaatactcc tctttctgag taaactaaat ccattatttg ttcccatgca
     4561 agcatactat tatataatct atctacttgt gtatttaaat cagcatttcc ttttgatatc
     4621 ccttgatata cagctgttgc aggaacattt aatgttactt tatcactttc aatatctgta
     4681 gtgtttaaca caccagtttt ttctgaatat ccatatgaat taccaacatt tgttcctgga
     4741 taatatggtt ctccttttac agcatcttta tatttagcta attcttctat atatgctttt
     4801 atctttttct tagattcaga aactcccgca ggactcttat catttattgt tccatttaga
     4861 ttaagatgtg gtatcttagt agctcctgct acacgtactt ttatatctcc tccacttgga
     4921 gtatcttcag cgtatcttat gtataaactt cctccacatt ctatatctaa actatgaagt
     4981 ttgcttaatt gaattacatt ttttccagtg ttaagattta tttctccact cttatatgca
     5041 ccagattctc catagtactg tgtatatatc aacttaggag tttttccact tttacttcca
     5101 acatatactg tgatttcatc tcctgctcta gcagctactc ctaatgcctg ccagtcattt
     5161 tgcataccta aattattgga atttacagta tactgtccat ttttatcttt atattttcct
     5221 aatttattta tttcttgatt tacagtagtt acatcagtaa gtgtggctct atcattatat
     5281 aagtcttgag ctaattttaa ttctctctca ataactgtct tatatggatg atattctcca
     5341 ctagctttat ctggagtatt taatctatct tttaattcag ttattttttc ttgagttaca
     5401 tcttctttta attcaacttg taggtcatcc ataaatagat ttcttacatc atcttctata
     5461 ctgtcatact cataaaactt aagttctgat atattagact tatatgaata ggatgagcaa
     5521 acacttactt gtattttggt agcagttatt ggttctttta atctaaccat tacatactta
     5581 ttattattta tagggtctgt ctttgtttca aaaggaacat cccccagatt gtgtaattga
     5641 ccattttcat cccaatatcg tacctcaaag tcatttattg tcttatcaga aacatcaaaa
     5701 cgaggtgtag ccataaaagt atccatagta taagatttat caaaagttat tattggtcct
     5761 ctattcgttc cctcagctgc attatatgtt gggaatgtcc aatgtgttgt aaagtcccca
     5821 tctactacat tgaatttatc aaatggattt ttatcactat attcgctttt gtcatatcct
     5881 gctggataag taacatctac aatgtgattt gttggtattc caaatccacc attctcttta
     5941 ggagtattaa ttaatctata gttaggtgtt gttggtgcat ccatgctttc agttgtacct
     6001 atatatgttt tagacattcc actagttccc aagtggttag tagctgtcat tctaacttca
     6061 tatgttgtat tatccttaag accttctatc tttgaacttg tcccacgaat aagcttatca
     6121 ttgtatttta tccaagaccc attagaacct ttttctttat agtacaagtc aaagtcttta
     6181 gcttgtttat gatttttcca gcttacatca agagatttaa atttaccttt aacatttata
     6241 ccttctggtg gttctggttt tgtgtctgga acaacttgaa attctaatat actatctggg
     6301 ctaaattgta taggtttata gtttgaatct acattttctg gtactccgtc taagttttct
     6361 ggtgttgcat ctttataacc actagaccaa tctccattta aagattgtat gctaacccta
     6421 tatagtccat atgcttctat atctctaact tctattgtat ttttactagt ttgtaatttt
     6481 ttagtagata atacttttcc cttactatca attttgtcta gtataagttc gtatgctgat
     6541 acatttactt cattattcca ataaaaagat attttttcat ttccaacagc agtgctagtc
     6601 gatattttat ttattttagg tatattcatc tctggttttg gtatttcttt atatacattg
     6661 tttaaaaatt caacttttga tatttctgca agatttctat catttgctgt tgtagctgtt
     6721 atttttatag ttatcttttt tactgctact tgtttaccaa gatttattac tatatcacta
     6781 ttttgaacat ctgcatatgt ttctaatgct gacctactat atgtagatgt tgtaaagtta
     6841 tcatctttac tgatattatc cccttctttt ggagtatctt catctgaatt aggtttatcc
     6901 attgatgaat tttctttatc attattttta tcttgattgg tattagagtt tgcttcttgt
     6961 ttatcgctat tttcctgttg tttatcatta ttttcatctt tattatttga gttattatca
     7021 gtctggttta tattttcatc tttattattt acttcttctt gatttacttc ttcttgttcg
     7081 ttatttactt cctcttgttg ctcctcatct tttaagtttt tcatatattc tttgttttca
     7141 taaggaatct gttgaatatt accatctttg tcagtaacct caactattcc ttttgctgga
     7201 gcagtacctt ctggagcttt tatattgatg acttccatat taagtgcttc tgataaagct
     7261 atatccatta ctgctggttt ttcctcagat atttcatcat tttttgaaga tattgtaact
     7321 ccattatttt ctccactaaa taaattttct acattaccat taatatctac atcactattt
     7381 ccttttaatt caaccttact tgtatctact ataggattgg tagatactat actttctagg
     7441 ctttttgcat cttcactttg tcctaaattt ttctgtacat aatctaagtc aacaatatct
     7501 acctttccat ctctatttaa atcaaattct cttttatttg aatctatatt ctctaaaacc
     7561 ttattataat cactcttatc tactttaccg tctccattta catcacccat taagaataat
     7621 tcataattta aaggtttatt tttattatct acacttgctc tattgcttaa taagactctt
     7681 tgtgaataac ttgatatatc aatgtcttta atttctttgt tcttaaatcc agctccagag
     7741 acttctacat tgtattttcc aacaggtaaa ttattaaata caatattata atatgatata
     7801 ttctcatctt tattttttat ttcacttcta cttgcagata atttttttat agtatattct
     7861 atattatctg tcccaacatt tactgttcct gaatcttttt ctccaagctt tattattcca
     7921 ctattgttac tatcatcttt taatcgtaac tgcatattag tcatactttc tgactcgcta
     7981 ttttttattg gcagtgaaaa atttaaatct acttcaagac tcccccttaa cttttctgta
     8041 actgattttt caactgccct tagcttcccc tctaatatag gttctgcaaa aacgtttagt
     8101 ggtgcactac acatagatac tgctagtaca caagatattg cctttttcat gaaataacaa
     8161 tcctccctta ataaatatct aatttttcat gaatttaaat actataagtt tcagacaata
     8221 aaaaaagaca ctcaaagaga atcttaatta taaaataaaa agactttact ctttttagca
     8281 actggctgat atggctttaa aagctttaat ccctatagtt ttgcgtcatt agatttccct
     8341 aattttgcca tttaattttc actactttct tacccatttt atactatatt taaacttttt
     8401 aatacaattt ttttagatta aattataaaa aaataacatt tatattaatt tattaatata
     8461 aatgttattt tccattataa tttaattatt tatatagctt ccttacaagc ataattttgt
     8521 gtatattttc ttattcttta tatcttccat aaaattcatg tgtagcatat agattcttat
     8581 ctcctgttat agctatacca aatcccatta tttcataccc tttatgcaac atattagttc
     8641 cttcttctgg atttgtcttc cactcattaa aaataaagtt tcctatatca tctgcatctc
     8701 tatttgtata tacaggttta tctggaattt tatatttaat tatattttca ccttgaactg
     8761 ctatatatcc aggtttaatc tcactccaat ctaagtattt caaaaaagta gaatatgaat
     8821 tttttccatt tatcgtatga gataaagtct tcttatttgc cattaaatta gaccaatcat
     8881 ttgctagacc ctctaatctg cttgctacag ataacgctct tactccattc tcttttctat
     8941 actgctttgt aagagcatat actttaccct ttattctctc tttaaatgct ctatcatttg
     9001 gattgtaata taaaccttgt tgatttggtg aagcttgatt tatacattgc ttgataacat
     9061 tctgatttat gcctcctagt acagtcaatt tgtctgcacc acttaaaata ctcttgttac
     9121 tgccattttc aactaaaact acaggagcat tttttgctat tgtagaggca gccaaagcgt
     9181 ctgttaattg taagccttta cttagataaa attctttact atttttataa aactcttgta
     9241 taactatctt attagtttca aatctatctg tgccacccaa tctaatagaa tttgtgctct
     9301 taactaattc gtcgctgatt atttcactag aaccaagcgc ataactcttt aagcctgtcg
     9361 tgtcaaatcc cacactattt ccatctgtaa gtattatagg tactccatct ctagcagcta
     9421 ctggtgatgc acttatcgca tctgcttctc ctgtaaatcc attggctata attactttat
     9481 ctattggctt aatttctttg attttttcag ctatttttat acttgtatca aatctatttt
     9541 caccaaatat tctttgtaca accttctttt tggatagtaa ctgattctca acatttttac
     9601 ttattgttga ttctgagcct attatataca cagtctttgc tttgtttaat ctttccatag
     9661 ttgtgtttgg aatctggttt tgttttgtca tcaaaatagg cgcatttaag gctccagcta
     9721 aaccacttgc acttagacca tctgctaagc tattatctga gttgattagt attgctgtat
     9781 tgtagttttg cttatctgct atttttgctg ctgtctcata tctgtcattc ccttttattt
     9841 gctcaactga tgtcaacgca tttaccatag gagtatttac cattactaaa aatagtgtaa
     9901 gtcctatagc taatatcttt ttactattct tcatattatt ttctaccccc aatgtacttt
     9961 tcatattttt tattagtact catacttatt tttaatcaaa agttacaatt ttgttaccat
    10021 attttatata tgataccata gttatccata caactcaaac aatataccta aagtttttat
    10081 tctctataaa ttcaaaacat tataatttat tttatttaat ta
//
LOCUS       DAEOTL010000118         9934 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEOTL010000118 DAEOTL010000000
VERSION     DAEOTL010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.120"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            298..2175
                     /locus_tag="KRH82_003524"
     CDS             298..2175
                     /locus_tag="KRH82_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8656778.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQENQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEIIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFDFGQVVSCKSSYVSTNDNIISLVLAG
                     N"
     gene            2485..3891
                     /locus_tag="KRH82_003525"
     CDS             2485..3891
                     /locus_tag="KRH82_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBG8656779.1"
                     /translation="MNTGFPKDFLLGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHSFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            3919..4767
                     /locus_tag="KRH82_003526"
     CDS             3919..4767
                     /locus_tag="KRH82_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBG8656780.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            5428..6120
                     /locus_tag="KRH82_003527"
     CDS             5428..6120
                     /locus_tag="KRH82_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656781.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            6117..7052
                     /locus_tag="KRH82_003528"
     CDS             6117..7052
                     /locus_tag="KRH82_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8656782.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            7200..8123
                     /locus_tag="KRH82_003529"
     CDS             7200..8123
                     /locus_tag="KRH82_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656783.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            8107..8877
                     /locus_tag="KRH82_003530"
     CDS             8107..8877
                     /locus_tag="KRH82_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656784.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVPKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            8887..9669
                     /locus_tag="KRH82_003531"
     CDS             8887..9669
                     /locus_tag="KRH82_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656785.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
BASE COUNT         3476 a         1295 c         1868 g         3295 t
ORIGIN      
        1 taccatttag attttttaat caagtacttt ctctattaaa aaaaatttaa atatataatt
       61 attatttaca aaaaaattat actttatagt tgaattaaga aaacgcttat gatactataa
      121 agttaacaaa tttgaatata taacagtaga cgtgttactg gtaatgcagg caagatcgaa
      181 tcaattttta tagattatct atagagtact atgggtataa tctatttatt tggttcgatt
      241 tttttgttta attggccata aaacaaaaag cctatagttg aaaatggagg attttttatg
      301 gattataaaa atatagctca agaaattcta ctaaatgtag gaggaaaaga gaatgtaaat
      361 gaagtgactc attgtatgac aagacttaga tttaaagtca aaagcgcttc taaagtgaat
      421 aaggataaat tatctaaaac tgaaggagta ataactgttg ttgagagtat gggtcaaata
      481 caagttgtaa ttggaaataa agtaaaaaaa gtatatgacg aggttataaa aattgtacct
      541 caatcaaata acgtaggtaa aaagaatgaa agtcaagaaa accaaggtat aattaattct
      601 atattatcag cagtagctgg tatatttaca cctacaatac ctgctatagc aggggttggt
      661 atgattaaag gtattttatc agttcttgct atgtattata tgaataaaaa tggagtagat
      721 ataaaagaaa cgcaaagcta tattatctta aatgctatgg ctgattctat attctatttt
      781 atgcctatta tactaggata tactgcggct aaagtattta atgcaaataa aataatatct
      841 atggtattag gagctacact ttgttatcca acttttactg ctttgatggc aggtgaagaa
      901 tctgttagat ttttaggatt ggcagtaaca aaagctacgt atacatcatc tgttattcca
      961 ataattattg ctatatgggc tctttcatac gttgaaaaag tattagaaaa gtatatacct
     1021 gagataatta aaataataat ggttccaact ttatcattgg ttgtaatgtt acctgcaaca
     1081 ttatttttat ttggaccaat cggaatttat ataggaaatg tcataaactt ttcttataag
     1141 tatatttatg aattaagccc agcattgtgt ggagcatttg taggtgggtt atggtgtgtg
     1201 ttggttatat ttggtgctca tagagcatta ttaccaatag gtataagtga tgttgctcaa
     1261 acaggaagac agaatctatt ggcgtttgca ggagctgcaa acttttcaca agcaggggct
     1321 gctctaggag tattctttaa aactaaaaat caaggactaa aaacaatttc tatgtctgca
     1381 actataacag ctttatttgg tataactgaa cctgcaatat acggtgccaa tcttagatta
     1441 aaaaaaccta tggtatgtgc cgtaatatgt ggtgcatttg gaggtgcgat aatgggaatg
     1501 ggtggagctt atggtaatgc atttgcaaac caaggtgttt taactatacc tgtatatgct
     1561 gaagcaggtg cattaggttt cttaagttat ctaggtggtt gtgctatagc attttttggt
     1621 tcagctattt caacttatct agttggattt gaagatttgg aagagtcttc taataaggaa
     1681 aattcatcta taaaagtaga aacgaaggat ggtgttattg atataacttc acctgtagag
     1741 ggcgaatgta tagaattgtc agaagtaaag gatgatgtat ttgcttcaaa agctatggga
     1801 gaaggtatag ctgtgttacc tacaaaagga gtaataacag cccctactga ttgtgaagta
     1861 gcttctttat ttccaacatt acatgcaata ggattaaaat tagataatgg agcagaaatg
     1921 ttaatacatg ttggaatcaa tacagtagag ttaaatggta aatactttac aaaacatgtt
     1981 aatcaaggag atttagtgaa aaaaggtgat aaacttatat cctttgatat agataaaata
     2041 aaaaaggctg gttatgatgt aactacgcca gttatagtaa acaatacatt tgattttggg
     2101 caagtagttt cttgtaaatc tagttatgtt tcaaccaatg ataatataat ttcattagta
     2161 ttagctggta attaagttaa tttgactaga gataagtaaa ttgatttaaa aggaaataag
     2221 taaatcaaca attaaataca tctaaaagta agtttattgc aatgaattgt taaagaaaat
     2281 aattaatatg gagtaaatct attgcaatga agtaacaaag aaaataatta atatagagta
     2341 agtttattgt aatgaattgt taaagaaaat aattaatata gggtaaatct atctcaatga
     2401 aataacaaag aaaagagtta atatagagtg aacttattgc aatgaatcaa caaagaaaat
     2461 aattaataaa aaggagaaat atttatgaat acaggatttc caaaagactt tttattggga
     2521 gcatcatctt ctgcatttca agtggaagga gcttgggata aagacaataa aggaaaaacc
     2581 gtagccgact ataattcttt taaaaagtct catttacagg cagatactaa agtcgcatca
     2641 gacttttacc ataattatga agaagatatt gaattaatga aagaattagg gatgaaaaca
     2701 tatcgttttt caatttcatg ggcaagaata ataccagatg gtgaaggaga gataaaccag
     2761 aaaggtttag aattttataa taagataata gacaaactaa tagagtgtga tattgagcca
     2821 ttcgtaactt tataccattt tgaccttcca tttaaattag tagagaaata taatggttgg
     2881 gaaagtagag aaactgtcta tgcttttgaa agatttgcta aaatatgctt taagcatttt
     2941 ggagataggg taaagtattg gcaacctcat aatgaacaga atttaattgt tagagtggag
     3001 gagagaatta atatatatga tgaaacagat tcatggaaga tagataaaat gcgtgctcag
     3061 atggattata atctttgctt agcacatgca ttagcagtca atgcatgtca tgagatgata
     3121 aaagaaagta aaattggagc agcagtatca tcatctgtaa catatcctct tacttctaag
     3181 ccagaagatg tatatgcagc tagaatgaat gataatttta aagtgtacta tatgcttgat
     3241 atgcatcatt atggagaata tccagggtat tatatgaagt atcttgaaaa aagaaatata
     3301 gttcctcaca tggaagatgg ggataaagag atacttaaaa aagctaaaat ggattttata
     3361 gctgtaaatt attataggac aaattgtgca gaagctttac ctgaagattc acaacattca
     3421 tttggattaa gagaaggaac tgttgatttt agtatgtatg gactatttaa aatgtcaatg
     3481 aatcctaact tagaggcctc tgagtatgga gcagcaatag acccatcagg tcttagagtt
     3541 gccttaaatg aatattggca aagatatcac ttacctgtta taataacaga aaatggtcta
     3601 ggagctaaag atatattaga agatggaaaa attcatgatg actatcgtat agactattta
     3661 agaagtcata taaatgcatg taaactagct attgaagatg gtgtagagat gattggatat
     3721 tgtccatggt catttacaga ccttttaagt tcttctcaag gttttaataa gcgttatgga
     3781 cttgtttata taaatagaac tgaccatgaa attttagatt taaaaagaat caagaaagat
     3841 agtttttact ggtataaaga agttatagag aacaatggaa tagtaaaata aacataaata
     3901 tatattgagg gttttagtat gtacattaca aaggtattaa ataattcgtt gctacttgca
     3961 aaggatgata atgatgaaga aataatattg atggggaaag gcattggcca taattataag
     4021 gccgggtctg agttaaataa aaaagatata gaaaagattt ttgttcttca tgatgaaaat
     4081 ataaaaaaga gtattataca attggcaaca gaaatagatg cagaatattt tggtatagct
     4141 caaatgataa ttgcatatgg aatagaaaaa tataacttaa aacttatgaa ccatatatat
     4201 ttggccttaa ctgaccacat tgcctttgca gtgagacgtt ttaaagaagg tataatgatt
     4261 gaaaatcact atttgttcga aatcaaggaa tttaatccaa aagagtatga tataggaaaa
     4321 tatgctatta ctgtttttaa ggaggttctt ggtttagacc taccagaaga agagattggt
     4381 aatatagcag gccattttat aaatgcacaa caagataatc cttatagtga tagaaataag
     4441 agaagtgcta aaattgtaaa tgctattttg caaatagttc attatcactt ttctattgta
     4501 tataataaag agtcatttta ttataggaga tttgtaatgc atctaaaggc cttttcacaa
     4561 agatttctgg ctaatgaacc atcaagagaa aaaatagatt ttatatatga gcaagttcaa
     4621 aaaaattgta aggaagagta tgaatgtgtg aaaaaggtag gagcttatat gtataaggaa
     4681 tactccagag aattaccaag acaagaggag ttatatttga tgattcatat tcataagatt
     4741 ttaggagaat tatgcgaaaa tagttagaat atcttaatat gctagtaata ttataaaaaa
     4801 ttaaaaatta actgcacttt aaatatgaat aattgcatta cttaaggggg ttgtcttaaa
     4861 attgattttt ttaattaaat ttgaagctca actccttttt taaaccttta tatcattaca
     4921 actttaatgt ttatacgcct gtactttaga tgtatatcta ctttttacat ttctcaacat
     4981 gcaaacctac cattttttgc agtatgttaa ttgaaataaa ccattgagtt aaccctaaat
     5041 ttattctgga cttataggaa tagttccaaa gatactttaa aatattttct ggaataattg
     5101 cttatttcac atatgtttta ttgtgatgtt ttgatttaat aaattcttca actctgtata
     5161 tagtaaatgt attatcatgt ttgttttatt caagcacact tataatacgc ttgatttttt
     5221 cacaatgatg aaatatacta atgggtgtta taggtataag aatcgcatta cacttgaaga
     5281 agtaagtgat aaatgagata taaatcctca tatgataaac tactatttca ttgaggaaca
     5341 tattctaagt gatgtcaaga tactacaata tgactaaatt cctagtgata aaaaagtcta
     5401 cgaatgagtg tagaaagggg aactaagatg aataaagttt taattataga tgatgataaa
     5461 gatctttgta ttttgttaaa aaagagtatt tcaattgaac agattgaagc aaactattgc
     5521 cattctggga gagatggact ggttgaactt tcaaaacaag attatcagtt agtagttcta
     5581 gacgtgatga tgccaggtat ggatggtttt gaaactatgg aacaaatacg aaaatatagc
     5641 agtattccca tcttaatgct gacatcaaaa agcgataatt acagcaaagt gcatggattg
     5701 cgagctggtg cagatgacta tctaaccaaa ccatttgaaa ttacagaatt tactgctcgt
     5761 gtactgtctt taatccgacg ttacacccgt tttaatccaa aaaatgagga gccacagcaa
     5821 ctttctttca aaggtttgtt gattgacctt gaccagcata cagttactac caatggcgaa
     5881 cctatgttgc ttccacccaa ggaatttggt gtacttcttt actgtgcaag gcatcagggt
     5941 aagattttga caaaacagca gatttatgaa gccgtgtggg gtgagccata tgtatatgat
     6001 gacagcaata tcatggctat tatcagtcgc ctaagaaaaa aaattgaact agacccatca
     6061 tctcccatct atttgcaaac aataaaagga attgggtatc aattcaacac ggaggtatga
     6121 aaatggatga acaaacgata attcttttct tactcttgct gtcgattggt ctactttttc
     6181 tttccatatt tgctttttcc aagcttgggc atatttacaa gcgcctaaaa gatatagagg
     6241 agatactggc tgatgtacaa attggagacg aaaatcgtaa aatactaatt aagccatgtg
     6301 atgttatggc tccattggtt tatcagctta atgagattgt ctacgattat gaaaataagt
     6361 tactttctct gaaaaagtcg gataaagcta gcaaacaact tatgacaagt ttatctcatg
     6421 atgttcgtac accattaaca actctgattg gttatctgga tgctgtacac agtggtatag
     6481 ttatcgaaca agagcgggag gaataccttg aaatcgctag gcgtagagcc tacgacctca
     6541 aggattacat tgatgttctt tttgactggt ttcggttgaa ctctgatgaa tttacgctgt
     6601 caatagaatc tgtggaaatt gcagagttgt cacgcaatat tttgaaagac tggattccta
     6661 tattccatga aaagaaactg aattttgaaa ttgatattcc agaaaatcga ctaatggtaa
     6721 acctcgaccc agatggatat tcccgtgtgg tcaataatct ggttcaaaat gttcttgctc
     6781 acagtaaggc tcggcaaatc aaaattacca tgagtgagga ttccagaatg gtattactcc
     6841 gtgttgagga tgatggtgtt gggattgcca gagaaaattt accacatatt tttgagcgac
     6901 tgtataagtg tgataaagga cgttcagaaa aaggaagtgg tcttggtcta tctattgtca
     6961 gtcaaatggt ggagcgaatg ggtggtcagg tttccgtaga aagtgagatt ggaaagtata
     7021 ccgtatttac agtgagctta ccattaatat aaaattgttt ttcccccatg tgacatgtat
     7081 acacaggggg attttttgta agttataaag ttgcaaggtt aatacaaggt tgttgcaagg
     7141 ttaatgtaag attgaggtgg tatgataact ttaataaaca aaggaggctt ttattattta
     7201 tgaataattt aattattgaa acaaaaaatc tcactaagca atatggtgct caaaagagcg
     7261 tttctaattt gaatattcac gttcagaaag gtcgcattta cggattgcta ggaagaaacg
     7321 gtgcgggtaa gacgacaact atgaaaatgt tattgggtct aacaaaacca actactggag
     7381 aaattaaaat atttggtcag gacattcaca ataacgagaa gaagcttctt cctcgaattg
     7441 gatgtttgat tgaatcacca gggttttatc ctaatctgac aggaacagaa aatctcaaaa
     7501 tctttgcaag gcttagagga ataccaaaaa aaaatgcagt agaatcagca ctggatgtag
     7561 tcggtttgcc aaacaatgac aaaaagttat tttctcaata ctctcttggt atgaaacaga
     7621 ggttggcgat tgctcttgcc attatgcatg acccacaact gttgattttg gacgagccta
     7681 tcaatggact tgatcctatt ggtattgcag aagtaagaac atttattcgt gatctctgca
     7741 cagaacgagg taaaactatt ttgatttcca gtcacattct ttctgaaatt gccttgttgg
     7801 cagatgacat tggcattatt gaccatggta ttttgttgga ggaagaaagt cttgcccaat
     7861 tagaagaaaa aaacagtaaa tacatacatt ttgctgtatc tgatgcagca caggcagcaa
     7921 ggcttctgga aacccaactt aacctgaaaa atttcaaagt agcagataat tacaatatta
     7981 tgctatatga tacagatgtt tctgttgcag aaataaatcg tgctttcatt ctaaacaaca
     8041 ttgaggtatc agaatctcat ttatgcgaag atactcttga agattacttc aagaaagtaa
     8101 cagggggtga aggaattgct tgatataatt tcatgtgaat tttcaaaact caagcggtta
     8161 aaatttatac tgatttctat tttaggtgct tgcttatttc caattcccgc aacaattttg
     8221 attgcaaagg ataacttgcc ctttgagcaa ttgttcaaat tagttgtcaa ttttggatat
     8281 tttttgctat taccaattgt attaagtatt gttgctagcc aactattttt tatagaaaga
     8341 gataatgatg tattaaaaaa tcttgcaaca gtgccagtgc caaaaggaaa actggctctg
     8401 gcaaaattgg ctgtgttgct gtttatatca ttgttctact ctgttgcagg gttaggagct
     8461 actatcattg gaggtttcat tgttggaata gtagaggggg ttgctgtaaa attaggaatg
     8521 agcattgctt ttggaattat gttttttgtt actgtacttc ctgttgtggt actcattgta
     8581 tatttcaatc gcagctatat tttttctatt atactttctt ttgtatatgc tattttcaat
     8641 tttagtatat ccttaaatat tatcaatttt gaaccaaata acccaatatt aagtgtatta
     8701 cctgctcctg ttataatgcg ttggtggatg gcattttggg gagatcccac tggcgaatac
     8761 acggcactta gacagccata tttgctctca actcctgctt gtgtaggtat tttatgtttg
     8821 ataaccatta tagcagtcct gctgatttgt atgatataca aaaagcagga gaattaggag
     8881 gtatctatgc ttgatataat tactacagaa tttcaaaaaa taaaaagata taatattcta
     8941 tggattggtg ttgttgctgt tctgttttca gcactattgg cagtttttca ggttgtaagt
     9001 tcacacggca gtgaccctct aacgtatgag agctttgcaa acggagttat ctggaataat
     9061 ttcagtctta gttttccatt tgggattaca cttattggag gatatcttat taaccgtgaa
     9121 tatacagacc aaaccttaaa aaacatccta actgttccta tttcattacg caaattgcta
     9181 gtgggaaaat taattgcggt tggaggaatt actgtattgt taagtctttt cagcttctta
     9241 tgcacattta ttttggggtt gttattttgt aatatcaata tatctgttac actcgttgta
     9301 aaatccttag ttcagatttt gtctgttaat ctgtattgtt atgttgctgt tttgccgatt
     9361 attgcttatt ttggtcgtaa acaaaatgca tttctgacag gtgtagggat tgcatttgta
     9421 tacggttttt gtggtgtgtt tgttgctgga agaaatctga cagactttta tccaatcaca
     9481 gcaggtcttg gtctagttgg atacaacaat ggtgctggta ctgtttatca gccacttatc
     9541 ggtgctatga ctttgattgt aattctaatc ttgacaacta ttctacttgt atttacacct
     9601 aattatgata aagttatgac catatctaag aaaaaaggga taaagcataa aaagtattct
     9661 cataaataac ataaatattg tttctattat ttaagttgct agacagtgaa aagaaaaaat
     9721 ctgtcgtaca gtggctatat gctcatgtat tcaagaagct acagttttga tttttcataa
     9781 ctgtagcttc tttttgtatt tattaaatca cgactatcat aatacttgca ataggtatag
     9841 cgacaagaga gagtactgtc atatgtgttt tatatattac attaagtata ttctaaaata
     9901 tatgttttaa ataatatatt tgaaaatagg aata
//
LOCUS       DAEOTL010000119         9433 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEOTL010000119 DAEOTL010000000
VERSION     DAEOTL010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.121"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(739..2145)
                     /locus_tag="KRH82_003532"
     CDS             complement(739..2145)
                     /locus_tag="KRH82_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8656786.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKEILHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2190..2897)
                     /locus_tag="KRH82_003533"
     CDS             complement(2190..2897)
                     /locus_tag="KRH82_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656787.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     KVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKEGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3068..3982
                     /locus_tag="KRH82_003534"
     CDS             3068..3982
                     /locus_tag="KRH82_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656788.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3982..4743
                     /locus_tag="KRH82_003535"
     CDS             3982..4743
                     /locus_tag="KRH82_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656789.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4755..5492
                     /locus_tag="KRH82_003536"
     CDS             4755..5492
                     /locus_tag="KRH82_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656790.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
     gene            6370..6639
                     /locus_tag="KRH82_003537"
     CDS             6370..6639
                     /locus_tag="KRH82_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBG8656791.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
     gene            complement(6857..7102)
                     /locus_tag="KRH82_003538"
     CDS             complement(6857..7102)
                     /locus_tag="KRH82_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBG8656792.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            7528..8226
                     /gene="tcdC"
                     /locus_tag="KRH82_003539"
     CDS             7528..8226
                     /gene="tcdC"
                     /locus_tag="KRH82_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBG8656793.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPSCSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            complement(8561..>9433)
                     /locus_tag="KRH82_003540"
     CDS             complement(8561..>9433)
                     /locus_tag="KRH82_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C80"
                     /protein_id="HBG8656794.1"
                     /translation="FAPANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRT
                     IDGKKYYFNTNTAVAVTGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQI
                     GVFKGPDGFEYFAPANTDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDG
                     NRYYFEPNTAMGANGYKTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQ
                     AIRYQNRFLHLLGKIYYFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIY
                     FFGVDGVKAPGIYG"
BASE COUNT         3346 a         1319 c         1244 g         3524 t
ORIGIN      
        1 actttctaaa tttcttgctt cttaagaata atgttaattt taattttaag attatagttt
       61 ttaccttgtt taattgaaac attctatata attatatcct tctattttag agttttttta
      121 tttatatatt acaaagttta aattttttca ttaattatat tataaatttt ccatatattt
      181 caacataaat acatatatat atatgttatt tctaaaaata ctacacaaaa actctacttt
      241 agtagaactt aatggcgcaa aatacttcaa tttaaaacat ttatcgtact ttaaataaat
      301 aactataata atatacttac aatagttaca tagaagctat tataactaca cagaacagcg
      361 tataattaaa acttttttag gatgtcatta tattttttct taaaattaaa aaacactata
      421 ccataattct attttagtag aatttttttg tcaataataa aattaaatat taactaaaaa
      481 ataaaaaaaa tggaattatc taaagaattt aataacctta caataattcc aaaatattat
      541 ttctatgaaa attttgatac catgagtaac tcagccataa gcgcataaag cacaagttac
      601 tctttacttt aataaaactt gacaagaaaa gaatttatcc ttattctact ctaatagagt
      661 taatttgtca ataaagaata aaattatttt caaaatattt tcattcttca ttcttatctg
      721 ttattatttt ataaaatatc acttaattag aggtaatttt agtattgttt ttagtccctg
      781 actatcaatg ctcgtaatat ctaatttacc tctatgtgca ttaataatgc cagatactat
      841 caaaatacct agaccatgat tttgaccttt ggcatatgcc tcacttagtc cattttggct
      901 ctttaataaa ctattaattc tttcttgact catacctttt ccatcatctt caacaattat
      961 atagcaaaaa tctaaatcag acttagaggt aacccttata ttacatcctt gttggttatg
     1021 agttatacta ttttgtatta aattactaat agcccttttt aataattttt tatctgcatc
     1081 tataataata tcttcattta gtatatcaag ttcaacgtaa aagtcattat ccaaattatt
     1141 atttataaac tcagaaataa gctctctcaa aaacgcagaa actctaatct tatcacaatt
     1201 caatgcttgc atattatatt caagtttaga cactaaattt aggtcattta ctaattctct
     1261 gattttaatc ccttgattgc atataataga cacttgctct tgttctctat ttgaaaggct
     1321 actgctttct tcaagttctc cagcatatcc aattatcatt gaaagtggag ttcttatatc
     1381 atgagatatt cctgcaatcc agttagacct agcttcctct ttcttcctaa gtttttcatc
     1441 tttcatttgc aactctttag atacagtatt aatagatttt gaaatatcac ttagtattcc
     1501 tttttcttgt aaaagtactg gctctccttt tgacataagc tttatgccag taataattgg
     1561 ttttatagat ttcaccattt ttaaacctat gaatagagct attaaaaaag taactattgc
     1621 attaaccaaa aacataccta ttattaacat aggaaattgt tctatttcct taaccgtata
     1681 agtaaggtta aacttagtgt acttgtcttt tggataacct gttactaata ttccatttgg
     1741 atgttcccat acatacacag gatagtcctt taaaaagaac cttgaaaact ttgctacatc
     1801 tgtcaaagta taatgacttg gaatttcttt tggtaaatca aatccccata ttctatctcc
     1861 attgttatca attaacattg cccaaacttt atttttatgt agtatttcct tactagaatc
     1921 atctaaaata aactttccat cttttaaaac caaattatct tcaatcataa tcaagtttga
     1981 ttttatttct ctgctatcac ttgtatctaa attatcagag tatttagata caaataacat
     2041 atatgaaaac agaagaaaac ctgctatatt taatacaata aaaagtaatg aaatcaagat
     2101 acttgaacct ataaatcgcc tcaatatgta ctttacacta tccaaaatta aatcactcct
     2161 cttgatttct tttattctaa tatctaaaat taattaatca tcaacttata tccaagacct
     2221 cttactgtaa taagatgttt aggtgtagat ggagtttttt ctatcttctc tctaaccctt
     2281 ctaacatgaa ccataagggt attttcatat ccatacatat catctcccca aatggcttga
     2341 catagtgaat cattagtaac aattctccct ttattttcat acaactttaa aagcaacgaa
     2401 tgctctttag ctgttaaaga aatctcttgc ccttctttct caacacatgc actatttaaa
     2461 ttcacaacaa cagaatctcc cagtttaaat actggcaact cctcttcttc tataggcaca
     2521 tatacacgat ttaatatacc cacaagcctt aaagtaagtt cctttggtaa aaatggcttt
     2581 actatataat cgtcagcccc taagcccaaa ccaatcaatc tatcttcatc ttcacctctt
     2641 gcagagagaa aaatcactgg tattttagat gtctctctaa tttttctcat aatagaaaaa
     2701 ccatctccat ctggcaatac aacatctaaa attgcacaat ctggctttac atttctaaat
     2761 accttaacag cttcctcata acttgatgct aaaaatactc tactaaatcc ctcttttctc
     2821 aggatttcat ctatcatttt taataattcc ttgtggtcat caaccacaag tattttttta
     2881 tcttttattg actccataat catcaccctc ctttagtata ccatataccc attttcacaa
     2941 ctttgcctaa atagactttt aaggttattg taaggtaaat ttcagctaat tgaaatgtaa
     3001 ccaagttatt atactgatat aagttaaaag aatcaataag cacagattaa aaaaggggat
     3061 gaaacatatg gaaatgataa ttagaacaca aagactttca aaggaataca ataaaatatt
     3121 tagagtaaag gatatagacc taagagttcc acaaggagct gtatatggtt ttttgggtcc
     3181 taatggagct ggaaaatcta ccactcttaa aatgcttctt ggacttgcta aacccacaca
     3241 aggaaatatt aatattttag gtaaagagtt aaatgaaaaa aatagaatat caattttaaa
     3301 agatataggt tctttgatag aatctccatc atactatggt catcttacag ggcttgaaaa
     3361 catgaccata atgcaaagac tcttagattt acctaaaaaa aatgtaaatg aagcattaaa
     3421 aattgtaagg ttagaaaatc aaaaaaataa aaaagttagt caatattctt taggtatgaa
     3481 gcaacgtctt ggtattgcta tggcaataat gaagtttccc aaattattaa tacttgatga
     3541 acctacaaat ggactcgacc cagcagggat tgaggaaatt agagaattaa taaaatctct
     3601 accagaaaaa tacgggatga ctgttctaat ctctagccat cttttaagtg aaattgacca
     3661 aattgccaca tcaataggaa taataaatca tggcgaactg gtttttcaag atagcataaa
     3721 agaacttcat aatagaggtc aaagtcagat tgctatcaaa actaagaatg ttgtatctgc
     3781 acaaaaacta ttaaatacta aaggatatat gtcacttata caagatgggt acttgactat
     3841 tgaaaattta aaagactcag atgtggctaa aataaatggt atgcttgtcc attcaaatat
     3901 agatgtattt agaatagaag aacataaaaa aagcttggaa gatatattct tagaacttac
     3961 tggtaaggcg gtgactttat aatgaaatac cttggtctag aattttataa acttaaaaga
     4021 aagaagatta ttctgatgac ctttttattt gcagctgttg aaataatgtg gtgtatcgta
     4081 aattcaaata gagctattac acgtaatcca gatatgttag gtggatttga atattcctat
     4141 atgcttatga gttttgcaag tttaaatggt ctattctttc ctatcttaat atcaataatc
     4201 acatcacgta taagcgatat agaacataaa ggagatacat ggaagctttt aaaatcttct
     4261 gtgacatctt taaatagtat ttatttatct aaatttttat gttctgctat tttggtatct
     4321 atacctgtat tgatgcaagt gttatctatt gtgttgtttg gacattttag aggggttatt
     4381 gagtcaattt ctgtatcttt acttttaaaa tacacattag gaacaattct tgtaagtatt
     4441 gctatcattg cactacacct atggattgca actgtaattc caaatcaaat gattgcaatt
     4501 acatttggca tgattggtag ttttataggt ttgacatcag gtttgtttta tcaaggtatt
     4561 cgtagattgt ttatatggtc ttattaccta gagttatcac ctttaagtta tgcttatgat
     4621 aatgttttag gttcatctgt ctatagaatt gatatgaatt tttctatcac gattttagtt
     4681 ttcttaattg gaatgctaat ttattatatt ggaagaaatc atttattaaa aaaagaagta
     4741 taggagggat ttaaatgtta aggaagtcag tcttgggaga aattctaaag ttaaaaaatt
     4801 cttttatatg gtatgtatta ttagctttgc cacttataag tgtgttgatt ggttctggta
     4861 atttttatct aaatcaaggc atactcaaaa aagaatggta cagcttatgg actcaagtta
     4921 gtctttttta tggggaattt ttctttccta tcttaattgc aatcttttgt gcatatattt
     4981 gtaggcttga acatatgaat cataattgga ataatgtaat gacactgcca gttaatttaa
     5041 aaaatatctt tttatctaaa cttacagtag tttcaatact tacagctatt acacaagttt
     5101 tctttgttat cttttatata gttgcaggaa atatgtttgg tttttctggt agtgtaccta
     5161 aagaattgac tggttggatt gctaaaggtt ggattatttc tatttcaata gcttctatac
     5221 aattatacat gtctataaag attagaagtt ttgcaactcc tattggtatt agtctttgcc
     5281 tttctctatt tggtatggga ttaatagtag caaaacctgc tgttggtata tttttccctt
     5341 attctatgtt aggtagtgct atgggggtta taaagcaatc tgctttaaat gttaatgaca
     5401 ctatagttac aatatgtgtt gcatttatta ctactatagt attttctgaa attgccaata
     5461 gaaattttag aaagaatgat gttatttctt aatggtaaat gctagatatt tttgggtttg
     5521 aaatttatat tctttttagt tgaaatctat atccatttta tttaaaaata tatatctttt
     5581 atttgaattt tatatgtttt atctactcgc tatataatag atatactcct aaaatttaaa
     5641 aatatataat aatattatta tttaaaatta ttatgtatta tattaaaact taatgcaaaa
     5701 acaattttta tattatataa tgaaacttaa ttaaatatag gtaaaaaatc attcaatata
     5761 ttaaataaat atttaacttt aataatctat atttaattat agctataaca tagaattatc
     5821 aaatatattg aatgaatatt tgaatcttgg aatgtgtaat taaattaagt ttggttattc
     5881 gatggaaggc aaatttgata taaaactcca tttaaagtgc cagataaaaa ctttatggtt
     5941 atataaaagt taaaagtaat ttatagtgtt atagaacatt caaagggatt taaagtaatc
     6001 tatggtgttt tgaaatattc aaagggattt aaactaatct atagtcttgt agaatattca
     6061 aagagattta aaacaatcta taatgttgta aaatatattc aaagggattt aaactaatct
     6121 atagtcttgt agaatattca aagagattta aagcaatcta taatgctgta aaatatattc
     6181 aaggggattt gaagtaattt attgtgtttt gaaatattca aaaagatttt tggaatagtt
     6241 tttataaatt taccagtact aataatttta tgtttaacat ttagatgacc taaaatcaac
     6301 tatttgcact tttgtattca tctaaaatca ttttataata tttttaaata atggaaagga
     6361 tgtttgaata tgtttgaatc aagatgtggt gtctgttgtg acagttgtac aaaaaaagaa
     6421 caagtaaatt gcactggttg cccaactatg gaaaaaccat tttggggtgg agaatgtaag
     6481 gttaaaactt gctgtgaaag taaggaactt aatcattgtg gtgaatgtga tactttccct
     6541 tgtgatatgc ttttaaataa gggaaaagac caaggttttg accctatggt aaatattgag
     6601 caatgtagaa aatggcttga agaaacagtt tctaattaat tgttttagaa tgctttgtta
     6661 aggaatttat ttaatccttt gttaggtagt atgtttagtc atttgttgat tagtatattt
     6721 atacatttat tgatgggtat atttagccat acaaatagat ttacataaaa tttacgacta
     6781 aaaaagagtt gagtattagt ttttattatt taaaacggat attcaactct tttttatgtc
     6841 taactttttt gattttttaa tctttccaat accaccactt taatttttct ggttctggat
     6901 tttcagttga tgcaaaatat actgcacatc tgtatacata taactgacat ctgtctatgt
     6961 gctgtccacg cattaaacat tccttttcat acatttgtgc tgggtttgca tctttaagtg
     7021 atttaatagt tgtatatcct aacatgatta aagatttttc tgttgctttc cctacccctg
     7081 gaattttttg tagttctccc atacttcacc ttctttctgg tatattcttt ttatattata
     7141 cctattacca gatatttttt tattatagtt aatatttaat atttaatttt ttattatatc
     7201 aatttattta tgctctttca tatatatata ttttaccacc tctaaatcac tgagtcactt
     7261 aattacatca taatatagtt ttatacaaat aaaatacttt atgtttaatt taatatataa
     7321 aattcacctt caagaaaatt atattataat ctgacatttt tatcttattt tttcaaaata
     7381 tattgaatct tcttacttta ttttgtaaaa ttatgcttag gggaaatata ttttaggaaa
     7441 atatgaatat ataattttta gtcaactagt tattttaagt ttttaacttt taaaataaaa
     7501 tatatctaat aaaagggaga ttgtattatg ttttctaaaa aaaatgaggg taacgaattt
     7561 agtaatgaag gaaaaggaag ctctaagaaa ataattaaat tctttaagag cacaaagggt
     7621 attgctctac tggcatttat tttaggcgtg ttttttggca atatatcctc accatcttgt
     7681 tctgaagacc atgaggaggt catttctaac caaacatcag ttatagattc tcaaaaaaca
     7741 gaaatagaaa ctttaaatag caaattgtct gatgctgaac catggttcaa aatgaaagac
     7801 gacgaaaaga aagctattga agctgaaaat caacgtaaag ctgaagaagc taaaaaagct
     7861 gaagaagcta aaaaggctga agaacaacgc aaaaaagaag aagaggagaa gaaaggatat
     7921 gatactggta ttacttatga ccaattagct agaacacctg atgattataa gtacaaaaag
     7981 gtaaaatttg aaggtaaggt tattcaagtt attgaagatg gtgatgaggt gcaaataaga
     8041 ttagctgtgt ctggaaatta tgataaggtt gtactatgta gttataaaaa atcaataact
     8101 ccttcaagag tattagagga tgattacata actataagag gtataagtgc tggaactata
     8161 acttatgaat caactatggg tggaaatata actataccag ggatagctgt agagaaaatt
     8221 aattaatatt gttttgtatt atagttaata ttttatatta tagtcaatat gtttaaagat
     8281 gtttttataa ttgcaaataa acagttacaa ggctctaaat tagtttttgc ttttagcata
     8341 ttatctattt tttatcaact attaattatt tagtattaat atttccatat atgaatttta
     8401 ttataaaata gtcaagaata atagattatt aaatgataga aaaattttaa ctaaaagtca
     8461 tgtattacaa taacacatga cttttaatta aatctcaata tttattatat aaaaataatt
     8521 tcttagtagc acaggaataa ttttttatca aacatatatt ttagccatat atcccagggg
     8581 cttttactcc atcaacacca aagaaatata taacaccatc aatctcgaaa agtccaccag
     8641 ctgcagccat agcagtatca ggcataaagt aatatacttt accattaata gtttgccatc
     8701 cagtaactgc ttttgaatta ttaccaaagt aatatatttt tccaagtaaa tgtaggaatc
     8761 tattttgata acgtatagct tgaccttcta tattgttagc atccgtatta gcaggtgcaa
     8821 agtattcaaa tccattagac cctttaaaca ctcctatctg aggtaaacca tttctaaagt
     8881 aaaaattttt attatcaata gttttataac cattcgcacc catagctgta ttaggctcga
     8941 agtaatatct attaccatca atagttaccc aaccagtagc cgcttttgaa ttattaccaa
     9001 aataatatat attgtcatgt aaatatagga atctattttg ataacgtata gcttgacctt
     9061 ctatattgtt agcatctgta ttagcaggtg caaagtattc aaatccatca ggtcctttaa
     9121 acactcctat ctgcataata ccatcagtat taaaataaaa atgtttacca ctaataattg
     9181 tataaccagt tgaagctata gaagtgttag tattaaagta gtatttttta ccattaatag
     9241 tttgccatcc agtaactgca acagcagtgt tagtattaaa gtaatatttt ttaccatcaa
     9301 tagttcgcaa tccggtaact gcttttgagt cactaccaaa gtaatatttt ttaccattca
     9361 aagttaagaa tttattttgg taaagtatag cttgaccttc tatgttatta ttatgagtat
     9421 tagcaggtgc aaa
//
LOCUS       DAEOTL010000120         9251 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEOTL010000120 DAEOTL010000000
VERSION     DAEOTL010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.122"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            227..883
                     /locus_tag="KRH82_003541"
     CDS             227..883
                     /locus_tag="KRH82_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656795.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDDM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(1391..2662)
                     /gene="sleC"
                     /locus_tag="KRH82_003542"
     CDS             complement(1391..2662)
                     /gene="sleC"
                     /locus_tag="KRH82_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBG8656796.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            2907..3623
                     /locus_tag="KRH82_003543"
     CDS             2907..3623
                     /locus_tag="KRH82_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBG8656797.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            3702..5012
                     /locus_tag="KRH82_003544"
     CDS             3702..5012
                     /locus_tag="KRH82_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBG8656798.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTRKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            5112..5648
                     /gene="lepB"
                     /locus_tag="KRH82_003545"
     CDS             5112..5648
                     /gene="lepB"
                     /locus_tag="KRH82_003545"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBG8656799.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            5814..6350
                     /gene="lepB"
                     /locus_tag="KRH82_003546"
     CDS             5814..6350
                     /gene="lepB"
                     /locus_tag="KRH82_003546"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBG8656800.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            6360..7115
                     /locus_tag="KRH82_003547"
     CDS             6360..7115
                     /locus_tag="KRH82_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBG8656801.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KDRISKLGLSIGIHLPMELNTCENIEYIRDSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            7189..8856
                     /locus_tag="KRH82_003548"
     CDS             7189..8856
                     /locus_tag="KRH82_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBG8656802.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
BASE COUNT         3461 a          938 c         1730 g         3122 t
ORIGIN      
        1 tagataatta aagggttagg gtgaaagagt aatcgtaaaa taaatatata gataatggtg
       61 gatagagtag taagaaaata aatagataaa gggatagaat aaatttaaat atggaaaatg
      121 aatatctaat aataagtgat taataaataa ttgtagatag attgtaaatt aaataaatct
      181 ttaatagaaa ggagaactat ttatatatta aatagtattt ataaatatga aaaaaggcga
      241 ttttatatgg agtggagttc ttatttgtat tattgctgtc ttagcaatac caagtagtag
      301 agaagtattt atggaagcaa caggtgcaca tccatatatt ggaggttttt taaagtttgc
      361 tgtattagct acaatgggag atttacttgg tgctagaatt ttgtataagg attggaaaat
      421 accagtagga gtattttata gagcaatagt ttggggaata ataggtgtag ttaccacata
      481 tggaatgtca atctactcat caggtgtagg tcaagcacaa gtggatgata tgcttccatt
      541 tgagggaata gcttttgcaa atgctctatt taagagtgca actatgaata tactaatgtc
      601 accaactgta tttttattcc ataaggttat ggactgtttt atagataaaa aatatgaggt
      661 tggaaagggg attaaggtaa aacttaaaga tgtggtaaat attgtggact ggaatgctta
      721 ccttggtttt agtgttttaa aaactatacc atttttctgg ataccatgtc atacaattgt
      781 attcttattc cctgctgagt atagagtaat tgcttctgca tttgcatcta tagctttagg
      841 tctaatattg gctttagcta ataagtctaa agttgcagtt taggttcact gatgaagata
      901 gtagtattat ttaaattagg aataactttt taaattaata ttatttgtat ttataataaa
      961 taataattta tataagaagt aatattctaa gtgatggata gtgttttaaa taataagaag
     1021 taatattcta agtgatagat agtgttttaa ataataagga gtaatactct aagtgagaag
     1081 tagcatttta aataataagt gagattttaa ataaaaagta ggtttttcgt tagaatagca
     1141 ttttattaaa cttaaaaata aatataatat tttaaagaaa tctaagttgc taagcactgt
     1201 ttttaagaag cttaaaatcc cccatttaaa gttttaagat tctaaaaaaa caagttataa
     1261 ctaaaaaatg gctgttaaga ctacaatact tataagtaat acttatggta tatattagtt
     1321 cataacagcc atttttattt taaattaata attttattca ataatttgag tttatgttct
     1381 aaatcaagct ttaaattaaa ggatttaaag aagctattct agttgtagct acataaactc
     1441 tggatatttc ataccatgtt ttaaaatcta ctactccgct ttgaggtaaa ccaaagattc
     1501 cttggaatat cttaacagcg ttttctgtat ctgttccata gataccatct tctataactt
     1561 ttggtacagc tggataagaa ttagatatag catttaactg attttgtatg gttctaacat
     1621 actgcccaga agaaccaact tgtagtgtag taccagggaa tgacactggt acaccactta
     1681 ctataggtgc tctttcaaat actatttcat ctccatagaa atatcttagt atactctcat
     1741 agtcatatcc ttggtcacct aagtctttac tgccccattg agtcatttgg tcaggacatt
     1801 gggatttttg tccatcacaa tattgtgcta atagtggctg tcttgatgta ggaggtcttt
     1861 ttataaaagt attaaaaata gcatctacaa ctacgttaat tggttcaaat aagtttctat
     1921 tatttataaa cttatggtcg tatgctgttg ttgaagttat tgtaaagtta tatcctttat
     1981 ttctatacca ttcagtaaag actctattta aagtaaatga tattatagct attacatttg
     2041 cataaattgt ctgttcaggc caagttgaat atatttcaga tgacgctatg tttttaatgt
     2101 actctttaaa tggaatccaa tagtttggag ctgatgaatc ttctggcaaa ccatcatgaa
     2161 ctactataaa ttcaggcact acagggttat ctaatacaac gaaaccagta ggaggaggta
     2221 atggttttaa gttactttct ggaatcttag gaggataagt accatataga gtatgttctc
     2281 ctatatcaaa aatcaactca ctttgtcttg agaaagaacg cttacttctt gttctaggag
     2341 acatgggaac tccttgtctt gcttcaattg tagctaacaa ctgtgttcct tctatgacaa
     2401 ctgtctcata tccatctgct atggcttcca ctatatactg gctataaggt ctaacatcag
     2461 atggttgtag agagtaatct acatctggtg ctggtaatac taaaccagtc acttgaccag
     2521 attcattact tcttaggttt tggtataaag ttgatgagct ttggctacca ttagacattg
     2581 aatatatgtt tactactgca ttttgaatag gtctattgtt agtagcatca attatgctta
     2641 ctgttaagaa accatcttgc atcaaatcac cctttcttta aatgaattta gttcccttat
     2701 atttcaagat atgaatatag cttgaaattt gttaaataat atagatataa atttaaattt
     2761 ttttgagtat ttgagtatat ttgtatttaa ataatttaaa ataatttaat gtatatttta
     2821 gtatgtattt aaaacacgaa taagttaaaa ataagtagat gatataaatc ataaataaat
     2881 caaaaatttt gaaaggaaaa taatctatga agctagattt atttttatta gcaatagttc
     2941 ctatattgat agggatgttt tggataaggt ctaaagatag atattgcaga gaacccctaa
     3001 tccatctaat taaatttttt ttaataggtg cttttctaag tgttataatt atacttttag
     3061 aaaatttact gatgaagttt aatgtatttg aagggtattc agaactaata tatgtatcat
     3121 ttgtagttgc aggacttgta gaagaaggtg taaaagctct gatactgatt cctgccctaa
     3181 ttaaagaaaa acactttact gaaaagttag atggtattat ttactctgta tttttagctt
     3241 taggatttgc aacaattgaa aatatggttt atattttttc tgaaagtaga aatctagcac
     3301 tgcaagttgg tattaatagg gcagttatct ctataccagc tcatgtaatg tttgcaatta
     3361 ctatgggcta ctatatttct aagtataaat ttgagggaaa taaaaataaa agacgtgagt
     3421 atttgtttat ggcagtgtta attccaattt tattacatgg agtttttgat ttcatattga
     3481 tgatagaata tagatgggct attatattac ttatagttta tgtaataatt ttgtggaaga
     3541 taaatcttga taaacttgag aaatatatga atcactctaa aaaagtgttt ttcggtaatc
     3601 ttaggaaaaa gaagaagaaa taaaatttaa aggaaagaca taaataatta aagtataata
     3661 aatgacacac aagtaaagca gattgaaggg ggattataga tttgacagaa ttaccaaagg
     3721 aatttttaga agatattgaa gaaatactaa aagatgaata tgatgatttt ataaaaagtt
     3781 atgaggaaag taagactact gggcttagaa taaatacttt aaaaattgac aagaaaaaat
     3841 tatttgattt ggagttgttt gatttgaatc aaataccatg ggcagaagaa ggtttttatt
     3901 atgatgataa aattgacaga cctggtagaa atccactgca tgaggctgga gcatactatt
     3961 tgcaagagcc ttctgcaatg agtgtaatac caaaggcaga tattaaagag ggtgaaaaag
     4021 ttctcgatat gtgtgctgct cctggtggaa aatctacata tatactatct aagctaaacg
     4081 atacaggttt attggtttct aatgaaatta atgctagtag aattaaggct ctaggggaaa
     4141 atttagagcg atttggagcg agaaattgta ttataacaaa caccgattct aatagcttaa
     4201 gaaagacgtt taatgggtat tttgataagg ttattataga tgcaccttgt tctgggcaag
     4261 gtatgtttag gaaggatgag gttgccatat cagattggag ttatgcaaag gtagtagaat
     4321 gtcaatccat ccaaaaagag attataagag atggatataa aatgttaaag aaggatggca
     4381 ttttaattta ctcaacttgt actttttcaa gggaggaaaa tgagcatgtt ataaatgagt
     4441 ttatcagtga atatccacat gcagaactta ttgaaatgga aagattatgg cctcataaga
     4501 taaagggaga aggtcatttt gttgccaaaa taaaaaaatt agaagaagaa gaatgtaatg
     4561 tcaaagaatt aaaaataaaa aatttagata aagaaataaa ggattatagg gagtttgaaa
     4621 agaaattttt aaaggttgat ttttatagta ataaaaaaaa taaattttat ttaagaggag
     4681 aaaatttgta cctacttcct gaaatatatc cagatacgag aaaactaaaa gtattgagat
     4741 atggtttgca tttaggggtt ttaaagaaga atagatttga gccttctcat gcactatctc
     4801 attacttaaa agttgaagat gtaaaaaatg ttgaaaactt cagtgtacag agtgaatcaa
     4861 ttcttaaata tttaaaaggg gatgttgtaa attctaatga tagtagagga tgggttttgg
     4921 tttcggttga aggaatacct ttaggttggg gaaaagaatc ttctggtgta attaagaatc
     4981 attatcctaa aggtcttaga aaagtatttt aaactattag aaaaaagaag tataatattt
     5041 atattgtagg tttatggtag attattttgc tgtagattga cttaatattt aacacagagg
     5101 agacgatttt agtgggtgaa gcagttaaaa aagaagttgt agaatggata aaagtgattg
     5161 tcatagctct tgttttggca tttgcaataa ctcgttttat agtgccaaca atagtcaaag
     5221 gagaatcaat gtatcctaca ttagttgaac gtgattattt gatagttaac agaattgcgt
     5281 acaaggtagg agagccaaaa tacaaagata taatagtatt caaaaccgac ttaacagagg
     5341 aaaatggaaa gaaaaaagat ttagtaaaaa gagttatcgg ggttcctggt gaccatgtaa
     5401 aaatacaaga ctccaaggta tatgtaaatg ataagttgtt agatgagact tcctatatac
     5461 ataataatcg tactgatgga gatattgata tcgtagttcc agaaggaaaa ttatttgcaa
     5521 tgggagataa tagagaaaaa agtttagata gtagatacga tgaggttgga ttggtcgacg
     5581 agcataccat tttaggaaag gttctagtca gattgtatcc attttctaag ataggaacta
     5641 ttgactaaac atataaaatt tggagcaatc gctgattagc tgaaatcacc agaccataca
     5701 caatagttgt ctatataaaa aagacaacac cttatttagt agacttatct aaaagatagt
     5761 gtttaagaga cattatcaat aaagataata taactataaa ggagaatttg tgaatgaatg
     5821 aaactattaa agaagagatt gtagagtgga taaaaataat tattactgca cttttttttg
     5881 catttattat aactcgtttt ataaaaccaa cattagtaaa tggagaatca atgtacccaa
     5941 cacttaaatc acatgattat ttggtagcaa acaggatgac atataagtta tcagaaccaa
     6001 aatgtggaga tataatgata tttaagactg atttattaca agagaatgga aggaaaaaag
     6061 agcttgtaaa aagggttata ggtgttcctg gtgaccatct aaaaattaag gattctaagg
     6121 tttatataaa tggtaagtta ttaaatgaag tttcatatat acatgataat tatactgaag
     6181 gtgatattga tatggtgatt cctaagggaa aagtatttgc gatgggagac aatagagaag
     6241 ttagtttaga cagtagatat aaagaagtgg gattagtaga tgaagaaaat attaaaggaa
     6301 aagttatttt aagagtattt ccttttacag atataggtat ttttgagtag gtgacttgta
     6361 tggcagttgg tatagcgtcc ttattgttta atattgagga ggctttaaac atttgtgaga
     6421 gtataaagca aataactcat ttagagattg gaattgacaa tatatctgaa tgtagtgagt
     6481 tatgtaaata taaagacaga atttctaagt taggattatc tatagggata catttgccta
     6541 tggaattaaa tacttgcgaa aacatagagt atatacgaga ttcatggata aattttattg
     6601 agaagataga atttgaacta aaaggatttg atttaaggta ttttaacctt catttgggat
     6661 atgttatgac aaatagagtt agaaagaata gagacaaata tttaggaaat agtgtggatt
     6721 ttttagataa attaaataca aattcatatg tatgtataga gaatacttat tcaaaaggtg
     6781 gggatttttc aaatattgga aatatatctt atgattttga atatatattt aagaggatta
     6841 aaaattctaa gatttgtttt tgttacgata ctggacactg tttaattgat gaggatgctt
     6901 atgtaaagaa cttaaaggat aaaataagac tgatacactt aagtgataat gatggtatca
     6961 atgatacaca tgttggtata ggaagaggaa ttttatctga agaggggatt aaagaggtct
     7021 taacattaga tgcagaatat ttagtattag aaataaatta cgaagacatt gaagatacta
     7081 taagtaaatt gaataatatt gtaggagagg gttaaatacc tctctttatc ttgttgatat
     7141 gcctcattaa ttaaaattta tattcatcaa aaggaaggag atgttgaagt gaaaaaaata
     7201 aacttaaaaa tagaaggaaa agataaggaa tattcattag aagaaaattc ccctggaatc
     7261 agattgggag atatagcaaa agaattttgt gatgagcata agggttatat aacacttgca
     7321 gttgtagaca ataaactaaa agagctaaat tgtagagtta agaaggattg tgagataaat
     7381 tttttagata ctactaatga agatggagag agagtttact ttagagtcat gtcatttata
     7441 tttgtaatgg catgtagaga aatcttttgg gatagcagag ttacaataga acattcacta
     7501 tcagatgggc tatattgtga agttcatata gatagaaagc ttaaagaagc agatgttgaa
     7561 aatataaaaa acaagatgaa agagatagta aacaacgatt atgttataga aaaaattgaa
     7621 gttacaagaa atgaagctat ttctatcttt gaaaataatg aaatgtatga aaaggcagag
     7681 cttttgaaat acaaagagta tgatagtgct aaagtatata agtgtagaaa ctatatagac
     7741 catttttatg gttatatgtt gccatcaact ggttatataa aatcatttga tattaagctt
     7801 tataatggag gcgttataat tttaggacct agtgaagaag ataagactct tcctatgaaa
     7861 tttgtacctc aacctaagct atcaagtgta tattatgaag cagaagaatg gtcaagactt
     7921 atgggaattg acaaggtagt atctcttaat aaaataatag aaaacaatga atatggagat
     7981 ataataagga catttgaagc attgcatgaa aagaagttat cccaaatagc ggatatgata
     8041 aaggatggca ataagagagt agttttaata gcagctccat cttcatctgg aaaaacaagt
     8101 tttgctcaca gattatcaat acatcttaga gtaaataatt taaatcctat ttcaatttct
     8161 ttagatgatt attttataga tagaaaacat actcctttag atgaatatgg aaattatgat
     8221 tttgaatcaa tttatgcaat agatttagag aagtttaact tagacttaaa gaaactttta
     8281 gctggtgaag aaattgatga tataagattc aattttaaag aaggtaagag agaatacact
     8341 ggtaaaaaga taaagataga ttcaaatcag ccaattatat tagaaggtat acatgggcta
     8401 aatcctattt taacatcatc tataccagat gaagataaat ttaagatata cataagtgcc
     8461 cttactcaaa taaatttgga tgaccataat cgaatcccta ctgctgattt gagaatgata
     8521 agaagaattg ttagagacta taattttaga ggatatagtg ctgataatac tattttacaa
     8581 tgggcatcag ttagaagagg agaaaagaag aatatattcc cgtaccaaga ggaggcagat
     8641 gctatattta actctgcttg tgtatatgaa ttggcagttt taaaacgatt tgcgaaacct
     8701 ttgttggaag agataaagga agataatcct gcacatattg aagctactag attactaaag
     8761 tttttgcagt attttgttga attggacgat acttctgaca taccaggtat ttcaattctt
     8821 agggaattta ttggaggaag taaaatagtt gattaatatg tgtattatag attgttttat
     8881 gaagattaaa tggcatagca agtagtgtga ttggtttatg ttaagtatat taagtgtaaa
     8941 gtggagaatt aaattgatac agattttaaa gtttgagttg atatataaaa aggcttgttt
     9001 tatacttttg tatgaagcaa gctttttatt ttaaatttta cttttttgtt taatattttg
     9061 ttagtttatg tgattatttt ttaaaagagt aaaagagtaa aagagtaaaa gagtaaaaga
     9121 gtaaaagagt aaaagagtaa aaggtgttgg gttagaaatt tttggtgtta taaaaattta
     9181 aattactgga ttattagatt gctggattgc taaattacta ggttgttaaa ttattgaatt
     9241 attaggttgt t
//
LOCUS       DAEOTL010000121         9191 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEOTL010000121 DAEOTL010000000
VERSION     DAEOTL010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9191
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.123"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            393..1598
                     /locus_tag="KRH82_003549"
     CDS             393..1598
                     /locus_tag="KRH82_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBG8656803.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="KRH82_003550"
     CDS             complement(1669..1890)
                     /locus_tag="KRH82_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656804.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="KRH82_003551"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="KRH82_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBG8656805.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="KRH82_003552"
     CDS             complement(2643..2993)
                     /locus_tag="KRH82_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBG8656806.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="KRH82_003553"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="KRH82_003553"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBG8656807.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="KRH82_003554"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRH82_003554"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="KRH82_003555"
     tRNA            complement(5068..5159)
                     /locus_tag="KRH82_003555"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="KRH82_003556"
     CDS             complement(5160..5615)
                     /locus_tag="KRH82_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBG8656808.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="KRH82_003557"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="KRH82_003557"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBG8656809.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="KRH82_003558"
     CDS             complement(7666..8547)
                     /locus_tag="KRH82_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBG8656810.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="KRH82_003559"
     CDS             complement(8559..9068)
                     /locus_tag="KRH82_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBG8656811.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2941 a         1599 c          975 g         3676 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttatttttt ttatttatca tgtattcttt atatttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt gtcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa gcttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgaa ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaagatattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ttacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatgatact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatttcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataacg tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctacaataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctcttttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttca ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcgccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tatttgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt tttttaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctacatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tatcgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatccct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtagc
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaattgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta agaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaagtata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggtgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta caatgacatc ttttataata ccacctaaat ctacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaag a
//
LOCUS       DAEOTL010000122         9164 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEOTL010000122 DAEOTL010000000
VERSION     DAEOTL010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.124"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(199..807)
                     /locus_tag="KRH82_003560"
     CDS             complement(199..807)
                     /locus_tag="KRH82_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBG8656812.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(916..3654)
                     /locus_tag="KRH82_003561"
     CDS             complement(916..3654)
                     /locus_tag="KRH82_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBG8656813.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3802..4593)
                     /locus_tag="KRH82_003562"
     CDS             complement(3802..4593)
                     /locus_tag="KRH82_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8656814.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4629..5285)
                     /locus_tag="KRH82_003563"
     CDS             complement(4629..5285)
                     /locus_tag="KRH82_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656815.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5278..6243)
                     /locus_tag="KRH82_003564"
     CDS             complement(5278..6243)
                     /locus_tag="KRH82_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBG8656816.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6349..6455)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6745..7689)
                     /locus_tag="KRH82_003565"
     CDS             complement(6745..7689)
                     /locus_tag="KRH82_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBG8656817.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7800..8267
                     /locus_tag="KRH82_003566"
     CDS             7800..8267
                     /locus_tag="KRH82_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656818.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8437..9036)
                     /locus_tag="KRH82_003567"
     CDS             complement(8437..9036)
                     /locus_tag="KRH82_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656819.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2993 a         1508 c          872 g         3791 t
ORIGIN      
        1 atacacaaaa aaattaattt ttatagctca tttcgccaaa atatatcttt ctttatatca
       61 ttaaaataat tataaattta ttaaatatgt ttgtaattct ataaagttat ttttatcaaa
      121 ctaaaaattc tataaaaaaa taagatacat acctataaaa taccttccta tagatacata
      181 tcttacctat ataaaaactt attctatata aaaacgccat aaaaaatctt ttgcttcttc
      241 tgcataatct atatttatac gtttactagt ttttatatct aactcatcct tactaaatac
      301 tttttttcct ttatcatcat aataaaaatc acttatatat aattcttcac ccattatact
      361 cttactattt agacttctat ctatttttaa agctttgcaa agttttcctg gtccgttagt
      421 aatatttttt acttgatatt tactcaactc agtgtaagct ttgttgtatc tattcataga
      481 tatctcatct aaagaagtta taggctctac ccctcttatt aatacacact ctggcacatt
      541 ttctatattt gcagataaat tcaagcaatt atacatacca taaattaaat aaacatatat
      601 atgtccacca tctaaatata atggcttagt tctatctgtc tttttattgc catatacatg
      661 tgctccttta tcatttacac ccatgtatgc ttctgtctct atgattttgg taacaattac
      721 tttattttca tatttcctta ttagatattt acctaatatt gatttggcta aatcaattcc
      781 attttttcta aaaaaatcct tttccaaaat ttcacctcat aaaatttatt taaaacgcat
      841 caaatacaac taaagtaata aataaaatta actcttatta atgtgatata tataaacaat
      901 aaatttagac atttattatt tatatatatc aaaaaattct atctcaaact tttcaatatt
      961 atcattgtaa tttgaattat catatacttc ttcaacaacc tctttaattg ggaatataac
     1021 ttttacatta gttccttctc ctaccttact atctatgtaa atcttcccat tttgaatttc
     1081 aatcaatgat tttgtaaggc ataaacctat accacttcca aattcatttg atataccact
     1141 gttttcaatt tgtttaaatc gattaaatat atcatttaat ttttctttgt ctatgcccac
     1201 tccagtatct tttataatta tctctactgt ttcgtctttt ttatatatac ctacaaggat
     1261 ttctcctcct tctaaagtaa attttatagc atttgataat atatttagta ttattctttc
     1321 tatcgattct gggtcaagcc ctaccataac agtttcttca tctgtatcaa aaattaaatc
     1381 tattccttta gacttagcat aactactaat agatgtaact attctttctg ttatgtcaat
     1441 aatatcaaaa ttaactgctt taatcttata tatgtctgac ttaacttgag aaatatttat
     1501 tatattatct attaatctca ataatctaaa catattttgt ttagttattt ttatatgttc
     1561 ttttagtata tcctgaaaat caattatttt tcctttttta taaaggtttt caataagttg
     1621 aactgaacta tatatattat ttaaaggtgt cttaagttca tgagatatat tagcataaaa
     1681 ctccatcttc atttggtcat actgtctttg ttttattaat gcttttttaa gtctttcaga
     1741 ctctctttgc acacttaaat ctttaataat tctcactcta cttcttttct gtccaaagta
     1801 taatgttctt gatatcattt ttacttcttt aatgtgatta ttttcattta ctatatggat
     1861 actcttctct ctttctccta tatttaaatt gtttatgtat ttttttacta atatatttct
     1921 atatttttgt gttgtaactc ctaatacatc actagaaatt ccgaacaact ctctaaatgc
     1981 tctatttgta tatagtactc ttgatgtact taaatcctca agaaaaatag cctctggtat
     2041 aacatccagt aatttttcat atattatttt ttgttcattt actgttctaa gaatatttat
     2101 ctctttagtt atatctctaa atgtaagcaa tttaaagagt ttattatctg accaatagtc
     2161 tccaactcta acttcttcaa catgctcttc accttctgag tcagacatca caaaattaac
     2221 tatacagttt gctgtgtcat tgtaacttac tatttcagct ttcttttctt gtgttagatt
     2281 taatctttta aactccctat tgtcaaagaa atctatgtta aaagtttcaa aatattgttc
     2341 taatgtcata tcgactaaat cacttgaaac acatttaaaa ctcttttcat attttttatt
     2401 tatacttatt accttattct tctttatgcc accttcagca cttcttacaa gtataggaga
     2461 tggaatattt agtataatgt tttcatagtc tttatttata tttcttattt cttcatctat
     2521 tttgatttca tttgtaatat catttaaact tattaagtaa ttgctttcat ctttattatt
     2581 acttaaactt aacaaataaa ttttatcatt taactctacc agtttatcaa ttatacttat
     2641 atcgttatca aatttcttca atttttcagc aactttttca tcttccttta taaaagttaa
     2701 tattttataa taattattca tatcctttga aaattcatct ttaaatttat tatttgtgta
     2761 acttatatta aaatcatagt ctgttactat ccatacattt ggtattgtat ccagagcttg
     2821 tctaagtaat tcttttctct ggtctatgta gttttttaat gttctttgta taatcatatc
     2881 cttttctatt gctaaattta tctttcctaa ttgctctgac tttttactta attttttatt
     2941 gattgaatca agttcataat atggatacac tactctatta ttaagactgt atacatatac
     3001 ataataagta tggttacata atagtaaata tattactcct attaatctat ctgaatctac
     3061 tatattaatc ttagaaattg ctacaaaaca tataatagtt gtaaaaaaaa caaaatatgt
     3121 taaatctttt attaacttat agtgctcaat gttactatca agtttattca acaaatatag
     3181 taaattaaac atagatatac aaatattaat taatataata atcatattcc agttaatatc
     3241 actaaaaata tttcttataa agtaatctaa tatcacaaaa gcactataaa aaattagtat
     3301 tgggcttatt cttagttttt ttactttaga aatggttaag tatataaaag tagacatatt
     3361 aattatgctt aagttaagca atacaatttg gaatttttga atttttaaat ttactactcc
     3421 taaaatactt acaaaaacta atacaagaca ccctactttc aatatattta taaattcatc
     3481 cgttttaaag ctacttatat aaactataga atatccaaat atccaaagta aaattattct
     3541 atacatattt atagaaactg tatacaaatt tatatttaaa agtgcaataa ccaaaaataa
     3601 cccattagct agtatataga ccttattctt acttaaagtt cctttagatt ccatattccc
     3661 caccacttct tcatttttat atagttttac ctataaatat gttaccacaa ttcttccaaa
     3721 aaatttgtca ctttctagtt ataaaaaaaa atgagtaaat atttttaatt ttactcattt
     3781 tgtagatttt gtatattcag tttaaaaagc tggaactata cttcctttat attcatcttg
     3841 tataaatttt ttaacttctt tactattcat agcctctgat aaagccttaa tcttatcact
     3901 atctttatta ttttctctac aagctattat atttacatat ggagaatcac ttgattctat
     3961 tactattgca tccttagtag gatttaagtt agctgttaaa gcataattag aatttattac
     4021 tgctccgtca acatctttta atactgttgg taattgctct gcattcattt cttttattac
     4081 tatattttta ggatttttag ttatatcttt tttagttata agctctccat cttttacttc
     4141 tatcaattta ttttttgcta ataatttaag tgctctagct ccattagttg catcatttgg
     4201 cacagctata acagctccat cttttaattc atctaatgac ttaacttttt ctgaatagaa
     4261 tcccattggc tctatatgaa ctttagatgt ataagtaagt ttatatcctt tctccttcac
     4321 agtttcctct aaaaatggaa tatgttgaaa gaagttagca tccaaagacc cttcatctaa
     4381 agctgtattt ggaagtacat aatcatcaaa tatttttact tctaaatcat atcctttttc
     4441 ttttaacaaa ggttttgcaa cttccaatat ctttgcatgt ggatttgatg aagctcctac
     4501 tagtattttt ttatcctctt tgtttgaaca acctactgct gatattgcta ttgctgacac
     4561 caatgctact gataataatt tctttaattt catttttact ccccctcttt aaaatgttta
     4621 taattaattt attttagttt cttataagcc agatttccta ctccctggat tatctgaact
     4681 aatattataa gtgctattac agtatatacc attactgctg tatcaaatct ttgatatcca
     4741 taaataagtg ctatattacc taatcctcca gctcctactg cacctgccat agctgtataa
     4801 ccaagtatag atattattga taatgtaatt ccagatacta ttgaaggcat agcttccttt
     4861 atcataactt taaatactat ttgtcttttt gtagctccaa aagattttgc tgcttctatc
     4921 aatcctttat caacttcatt taatgagctt tctataattc tagcgataaa cggtgctgcc
     4981 ccaatagtta ttggcactat tgcagcagtt tcccctatac ttgttccaac gattaatcta
     5041 gttattggaa tcattgcaac tataagtatc ataaatggga aacttctaaa tatatttact
     5101 ataaatccta atgcactatt tattgtgcta tttggtttta atccatctgg ttttgtaact
     5161 actaatatga ttgctaatat aaatcctaat attgttgcca ctatagttgg tactataacc
     5221 atatacaaag tttgtaacaa tgcatttgga aatagtgttg ttaaaaagtc aattaaacta
     5281 ttcatttatc atttcctccc atcttatgcc cttactagtt agatattgtt ttacttgctc
     5341 tccactttta tctgaaatgt ttataataag tgaacctaaa atatcatctt taaattgttc
     5401 taatttccca aatattatag acacatctat atttagttct cttgccatag tcgtaataat
     5461 agcttcatta gaaatatctt tagggaatag tatctttata tttgttcctt ttggcaatat
     5521 tatactttct tcacctatta attttctaag tcctttagta tttcttaaga atatttcttc
     5581 tgtatctcct acctctaata cttctccatt ttccattatt gctactcttc cacaaatctg
     5641 ctttataact tccatttgat gagttacaac tattattgtt attcccaatt ttttatttat
     5701 atcttcaagc aatgaaagaa ttgactttgt agtatttggg tctaatgctg aagtcgcttc
     5761 atcacaaaga agtacttgtg gatttagtgc taaagctcta gcaattgcaa ccctttgttt
     5821 ttgtccgcca cttagatttc tgggtttatc atttttcttt tcagatattc caactacttc
     5881 taataactct aaaactcttt ttttaatttc tgcctttgag tatccaaaac attctaatgg
     5941 caatgctaca ttatcaaata cagtttttct ttcaagcaat gaaaagtgtt gaaaaatcat
     6001 tcctaactct tttcttaaat ctctcatttg cttttcattc aatgacttta cttctttatc
     6061 agaaacaagt acactgcctt cttggtattc ttctaatccg tttatacatc tcagtagtgt
     6121 tgatttccct gcaccactat gacctattat tccaaaaatt tctccagatt ctatttcaat
     6181 acttacatct ttaagcactt gaatctttcc ataatactta ttaacatttt ttatgctaat
     6241 cataaaattt cctcccatat attctgctca gtttttatgt ttatcctctc ttatgtatta
     6301 caacaaaata aaagcccgag tataaactca ggcttagaaa gctatttata ctcatctatc
     6361 aactatatta gttgcaggat ttagcaccaa tgtatataaa atatactggt tgccgggttt
     6421 caaagggcca gtccctccac cactcttgat aagacgttat ttaatttaat tctattatca
     6481 tttgttgcta tgttatatat gatatattca ttaatagtat ttgtcaataa atttatttaa
     6541 attttttatt ttttattatc gttaattaac tatttttaat tagttttcta gctcctaaca
     6601 ctttatattt taatgtctat ataactatag aacatcatta taagaaataa attaaataac
     6661 atcaatctat ctaaatcatc tgtaaagtaa attaagaaaa ttaacatttt atccaaactc
     6721 tatcctacta ttaaataaaa taatttaaat acaatgatga ttatatagct ctagtacttt
     6781 agactttatc aaatgtttaa gttctatagg ttctattatt gtagcatttt tcccaaaagt
     6841 taaaaaatat tcagccaccc agttaagtgt agattttggt atatacatat ctatgtatcc
     6901 acctttagac aagattttca accctcttgc caacaaaaat tctgtttcac aacgttttac
     6961 tccctcatct gtcaaattaa ttttaatatg ataatctgta cctacttcca tattcttaag
     7021 ataatcatgt atagaagata aaaccttata tttcttactt gataagtttt ctatactcaa
     7081 aatcttcaca attctgtcta cacgaaattc cttaatagat tctgatttta tacagtaagc
     7141 tggacaatac caaagtccat tcatggcata caaaccaata ggaacaatgg tacgtacact
     7201 atttttttgc tttgatgaat attcaatttt aattgtagat tcattcatta ctatattaaa
     7261 caattctttc aataatggtg ttgaacagtg cctatctggt gtccaaaaaa caaatttacg
     7321 ccttatattc tcaatattat attgaatatc atttggtata caatttaaaa atttttttaa
     7381 aacagaaata gtttcttgct caaatggcaa atcattataa tattctagtg actgatatgc
     7441 aaagaatata gattttacct cactttctga aaatgcaatc ggtggaagta tacgctcttt
     7501 aagtacatga tatccaccag ccgctccaac ttttgaatat aatggaaatc caatactctc
     7561 cagcacctgt aaatctctta gtatagtacg ttttgataca gaaaattctt ctgctaattc
     7621 tcctgctgta aaacttcttt ttgcatttat tgttatcatc agttcaatta aacgctcagc
     7681 tcttgacata tttatactcc taatttaaat atagtgacaa taattgtcac tattatatga
     7741 taagatattc ttacatttaa atcaataata atagtaaaga aagaagggac tgatacttta
     7801 tggaaaataa tactattaag gctgatgata ttatcaatta ttgtctatca aacttagatg
     7861 atgttttatt aatgaatagt tggggggaac gagcaattta ttacaatcct aatggtattt
     7921 taaaacgagg agtatatgtt cttaccatta aagaaaaaga cagtaatcat gataaaggtt
     7981 cgttagttag tcgtccaaat gtataccgtg tgaatatagg attaaaaaaa gaaactttta
     8041 ttgaaatgtt tggatatatt ccaaagcgtc caggtgtagg tcaaatagtt gatatggatt
     8101 ttgattttac aaaattggac acaatcatgc cacatcctat ctactcatgg atgggatgga
     8161 tatgcgtcct aagccctact gaaaagacat ttgagaactt taaaacttta ataggagaat
     8221 cttacaattt tgcaaaacaa aaatttaaaa agagaaaaaa caagtaaaaa catatgaaaa
     8281 taatccctaa ataaatcata ataaaaatat taaggttaca agataaaaat taatatctta
     8341 ataacatgca aaaaagcgaa gccaaaaaat gtattattta taaggcttcg ctatatctca
     8401 aataatttat ttcaaatttc aaaactattt attctattat ttcttattat ttcctgttat
     8461 tcctaatcta tcattcatat cttttatcat ttttctaaaa ccactaccta tatcatttcc
     8521 aacatcttca gttccatgaa ctaattttat aaagtcattt tgaccttttt tcatatcttc
     8581 atcagatacc ttatctaatt tttctattct cttatctata tcttttacta atctttcccc
     8641 ttcagcgatt aggtcatcat tcattttctt taactctgta tcttctgttt taccgtcttt
     8701 tttaagagat gttacaaatg attgtatttt atctctacta tctttatatg cagcctttac
     8761 atcacttaga tatttttcat ttcctggata ttctttatct ttaaactgat tatttatact
     8821 ttctggagta tcataaatag aatatctatt tagacctgct atataatcat tatagcttgt
     8881 tgaataataa ttcatatatc cttcattatt atttacagat tcattaggat tttttcctgt
     8941 attttcactt ggtttttcat tatttttagt acatgcagtt atacctatag ctaatactag
     9001 tgctaatcct acaaataaag ttctttttaa tttcattttt attaccctcc tagatgtttt
     9061 atactataaa aaattttaat aattttcttt cttaatttag tatttctata tttttatatt
     9121 ttatttacta aaattaaaca agttataatt tatttttttg gaaa
//
LOCUS       DAEOTL010000123         9134 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEOTL010000123 DAEOTL010000000
VERSION     DAEOTL010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9134
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.125"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..381
                     /locus_tag="KRH82_003568"
     CDS             <1..381
                     /locus_tag="KRH82_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBG8656820.1"
                     /translation="SGELAQKVMNEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKA
                     GISLPRTAQAQYDATQHLPLSQAKAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGD
                     PIGFADLSSSYWQQHLIGAGRVKQ"
     gene            397..1308
                     /locus_tag="KRH82_003569"
     CDS             397..1308
                     /locus_tag="KRH82_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8656821.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYTWNNSKEAIEARTQA
                     ISGYLTKELQDLNIDTIRTDIPTSSTVTDVIVWHIEQSGTDTFSATYEVDQQIKEGEQ
                     TSNVKATYTVKVHVDADGDMVIVQNPTLAPAIEKSDYDPKTPETDASVDADTANDATA
                     FLETFFKLYPTATENELAYYVSGNVLEPIGRDYLYSELVNPIFTKDGENVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDSNWKIVG"
     gene            1429..1806
                     /locus_tag="KRH82_003570"
     CDS             1429..1806
                     /locus_tag="KRH82_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8656822.1"
                     /translation="MEIFINNHASIPIYEQISSQIKALIINGELKAGEALPSIRGLAK
                     SLHISVLTVQKSYDVLQKDGFIETTAGKGCFVSAQNQDFYIEEQQKKIEDRFVEAIEI
                     ARASGINLDKLIGLLKLLYEEDE"
     gene            1807..2670
                     /locus_tag="KRH82_003571"
     CDS             1807..2670
                     /locus_tag="KRH82_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656823.1"
                     /translation="MAENILEVKNLTKDYGDFVLNDLSFSIPRGVIMGLIGENGAGKS
                     TTVNCILNEIKKNSGNILIFGKDHIIDECEIKDKIGIVFDENHFPDIFTPKEIEKYMS
                     GIYTNWDSIAFRNYLKQFELPAKKKIKDFSKGMKVKLAFAVALSHKAELLILDEATSG
                     LDPIIRDDILDILIDFVQDENYSILFSSHITSDLEKIADYITFIHKGRLVFCSLKDDL
                     IDNYGVVSCGASVFDTLDKTEIISYQKEDYQYKVLVRDRNKIAKDFPKALVEPATIEN
                     IMLFYVKGELQ"
     gene            2667..3311
                     /locus_tag="KRH82_003572"
     CDS             2667..3311
                     /locus_tag="KRH82_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBG8656824.1"
                     /translation="MKGLLMKDLLVIQKKYGITRIIMDIFIIVALMLFLKGTGAIYIS
                     LLLIPVEIMTMIISLTTCDEQWKWGKYVVALPVSKTTIVKSRYIVALIMTCIGFGVAL
                     LVNTITYFIFPQFAFGYYMFIACASFAVTLVFLSFVLPSNYSLGVNAGFAVMFTLVII
                     LVVLAVWTNVTNNSILWFVVDNFELSIGIAFIIVIALAFSSYLLSKAFFTRKYN"
     gene            3324..3515
                     /locus_tag="KRH82_003573"
     CDS             3324..3515
                     /locus_tag="KRH82_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleic acid-binding protein"
                     /protein_id="HBG8656825.1"
                     /translation="MRKCLRCHEEMVENLDVKVDMQGYGIRITTKGVFGTTVEKPKVA
                     VCPKCGEVSLYIENFKSIK"
     gene            3720..3908
                     /locus_tag="KRH82_003574"
     CDS             3720..3908
                     /locus_tag="KRH82_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBG8656826.1"
                     /translation="MDKQLWVLCPICNNKTRTKVREDTELINFPLFCPKCKTETLINI
                     KHGKVTIIKEPDAKTQSR"
     gene            complement(4016..4375)
                     /locus_tag="KRH82_003575"
     CDS             complement(4016..4375)
                     /locus_tag="KRH82_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656827.1"
                     /translation="MRKAKETQTFDFRPLGLAIREARERAGLSRNDLGDKVFYGERHI
                     ADIENVGSHPSFQLFHDLVTMFNISVDEYFYPAENVVKSTARRQIETSLDLLSDNELK
                     IIQGTIDGILNSRESKK"
     gene            4562..4777
                     /locus_tag="KRH82_003576"
     CDS             4562..4777
                     /locus_tag="KRH82_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBG8656828.1"
                     /translation="MVVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDKALEEYIRKYLPDKL"
     gene            4794..5066
                     /locus_tag="KRH82_003577"
     CDS             4794..5066
                     /locus_tag="KRH82_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBG8656829.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            5068..5217
                     /locus_tag="KRH82_003578"
                     /pseudo
     CDS             5068..5217
                     /locus_tag="KRH82_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405294.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            5278..5619
                     /locus_tag="KRH82_003579"
                     /pseudo
     CDS             5278..5619
                     /locus_tag="KRH82_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578721.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            5744..6481
                     /gene="erm(B)"
                     /locus_tag="KRH82_003580"
     CDS             5744..6481
                     /gene="erm(B)"
                     /locus_tag="KRH82_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBG8656830.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            6627..6911
                     /locus_tag="KRH82_003581"
     CDS             6627..6911
                     /locus_tag="KRH82_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBG8656831.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECTFTLAEHFR
                     KKKLTKTNVKELLEGKETLVKGIKTKDRKSYNAVVKIGEKGYIDFISFSK"
     gene            7014..7892
                     /locus_tag="KRH82_003582"
     CDS             7014..7892
                     /locus_tag="KRH82_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBG8656832.1"
                     /translation="MIQYYYTKKEWGVVMEKEELKILEELRRILNSKNEAIVILNNYF
                     KGGVGKSKLSTMFAYLTDKFNLKVLMIDKDLQATLTKDLAKTFKVELPRVNFYEGLKN
                     GNLASSIVHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSTTIKSNLEELYKQHKEDNLVFQNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMLAYSMQ"
     gene            8340..8756
                     /locus_tag="KRH82_003583"
     CDS             8340..8756
                     /locus_tag="KRH82_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656833.1"
                     /translation="MKPSDFQKTVQCRFESCLKKVVRHVVKDYQKKLKRRQKGETLFC
                     ELPEIVVENLAVWDDYDTDYTIFNVCGSDIRICDDELAEALKHLSERNRENLLMYYFL
                     EMSDTEIAKRQNISRSGVFQNRHNSLELMKKILKEK"
     gene            8763..9011
                     /locus_tag="KRH82_003584"
     CDS             8763..9011
                     /locus_tag="KRH82_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656834.1"
                     /translation="MKHTMKKPSYYLLSQAMDGDEKAIEKILAFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGLIREALIKMILGFDIALEIEEE"
BASE COUNT         3250 a         1402 c         1773 g         2709 t
ORIGIN      
        1 tcgggagagc tggcacaaaa ggtaatgaat gaagcgttga agtatcaagg ctggaagtac
       61 gtctatggtg gtagtaatcc caacacttcc tttgactgtt cgggactgac acaatggtgt
      121 tatggaaaag ctggtatctc cttaccgaga acggcacaag cacagtatga tgctacccaa
      181 catctcccac tctcgcaggc aaaggctggg gacttggtat ttttccattc tacctataac
      241 gctggttcgt atgtaaccca cgtcggcatt tatgtaggaa ataaccagat gtaccatgca
      301 ggcgacccga taggatttgc agacctaagc agtagttact ggcaacagca cttaatcggt
      361 gcaggacgag taaaacaata gaaaggactt gaagatatgt ttaagaaaaa taagaaacag
      421 acagaaacta tcaaagaacc aaaagaaaaa aaggtgcgta ctgtcaaggt aggcacacat
      481 aagaaaactg tgattgcctt gtgggtggtg cttatcgcaa gcgtgagctt cggggtgtat
      541 aagaatttta ccgctatcga ccagcacacc acccatgaaa aagaaatcat tgagcttcgc
      601 ttgcaggaca ccaacgggat agaaaatttc gtgaagaact ttgcgaagtc atattacaca
      661 tggaataaca gcaaagaagc gattgaagca aggacgcagg caatcagcgg ttatctgaca
      721 aaggaattgc aggacttgaa tatagatacc attagaaccg acataccgac cagctccaca
      781 gttacagatg tgattgtatg gcatatcgag caatcgggaa cggatacttt ttctgctacc
      841 tacgaagtag atcagcagat aaaagagggc gaacagacaa gcaatgtgaa agcaacctat
      901 actgtaaaag ttcatgtaga cgctgacggg gatatggtaa tcgttcagaa ccctactctt
      961 gcaccagcaa tcgaaaaatc agactatgat ccaaagacac cagaaacaga cgcaagtgta
     1021 gacgctgata ctgcaaatga cgctaccgca tttctggaaa cattctttaa gttgtaccca
     1081 acagccacag aaaacgaact tgcttattat gtgtcgggga atgtgcttga acctatcggc
     1141 agggactacc tttattctga actggtaaac cctatcttta caaaagacgg ggagaatgta
     1201 aaagttaagg ttgctgtaaa attccttgat aatcagacaa aggcaacgca agtatcgcag
     1261 tatgagcttg tgctacataa ggatagtaac tggaagattg taggataatt gtaaaaggct
     1321 tgtatcatat ttttatgctc tgcaagcctt ttaatattga caactgtatt tttaagtatt
     1381 atgctgtact tgtataagct atacagtata gaacaaggcg gtgtttaaat ggaaatcttt
     1441 atcaataatc atgcaagcat acctatttat gaacaaattt cttcgcaaat aaaagcattg
     1501 attataaatg gggaattaaa ggctggcgaa gctctaccat caataagagg acttgcaaaa
     1561 tcattgcata taagtgtatt gactgttcaa aaatcttatg atgtgcttca aaaagacggt
     1621 tttatcgaaa caacagcagg caaagggtgt tttgtatctg ctcaaaatca agatttttat
     1681 atagaagaac aacagaaaaa aatcgaagat agatttgtag aagctattga aatagcccgt
     1741 gcaagtggca taaaccttga taaattgatt ggattattaa aattattata tgaggaggac
     1801 gagtaaatgg ctgaaaatat tttagaagtt aaaaacctta caaaagatta tggcgatttt
     1861 gtattaaatg acttaagttt ttccattcct agaggtgtaa ttatggggct tattggcgaa
     1921 aatggagctg gaaaatcgac cacagtaaat tgtattttga acgaaattaa gaaaaacagt
     1981 ggaaacattt tgatttttgg aaaagaccac ataattgatg aatgtgaaat aaaagataaa
     2041 atcggaattg tatttgacga aaaccacttt ccagatattt ttacaccaaa agaaattgaa
     2101 aaatatatgt cgggaatata taccaattgg gacagtatag catttcgtaa ttatttgaaa
     2161 cagttcgaat taccagcaaa gaagaaaatt aaagattttt ctaaaggaat gaaagtaaaa
     2221 cttgcattcg ctgttgctct ttcacataaa gcagaattac ttatattaga tgaagcaaca
     2281 agtggattgg accctattat tcgagatgat attcttgata tactgattga ttttgtgcaa
     2341 gatgaaaatt actctatttt gttttcatca catattacaa gtgatttaga aaaaatagca
     2401 gattatatta cttttattca taaaggacgg ttagttttct gctcattaaa agacgactta
     2461 attgataact atggtgttgt aagttgtgga gcaagtgtct ttgatacgct agataagaca
     2521 gaaattattt cctatcaaaa agaagattat caatataagg ttcttgttcg tgatagaaac
     2581 aagattgcaa aagattttcc aaaagcactt gtagaacctg ctactattga aaatattatg
     2641 ttgttttacg taaaggggga attacaatga aaggcttatt gatgaaagat ttattagtaa
     2701 ttcagaaaaa atatggaatt actagaatta ttatggatat attcattata gtagctttga
     2761 tgttattttt aaaagggaca ggagctattt acattagttt attgttaatt ccagttgaaa
     2821 taatgacaat gataatttcc ttaacgactt gcgacgaaca atggaaatgg gggaaatatg
     2881 ttgttgcact acccgtttca aaaactacga ttgtaaaaag cagatatata gttgctttga
     2941 ttatgacttg tattggcttt ggggtagctt tgcttgttaa taccataaca tattttatat
     3001 tccctcaatt tgcatttggt tattatatgt ttattgcttg tgcttctttt gccgtaacct
     3061 tagtattttt gtcatttgta ttgccttcaa attattcact tggagttaat gcaggttttg
     3121 cggttatgtt tactctagtg attattcttg ttgtattggc agtttggaca aatgtgacta
     3181 acaattctat tttatggttt gtagtcgata attttgaatt gagtatcggc atagctttta
     3241 taatagttat agctcttgct ttcagttctt atcttctatc aaaagcattt tttactagaa
     3301 aatacaatta gtgaggtatt gttatgagaa aatgtcttag atgtcatgaa gaaatggtcg
     3361 aaaatttaga tgttaaagtt gatatgcagg gatatggtat tagaataact actaaaggcg
     3421 tttttggaac tacggtagaa aaacctaaag ttgcagtttg tccaaaatgt ggcgaagttt
     3481 ccttatatat tgaaaatttt aaatcaataa aataaatgat taaaatctgc atatagactg
     3541 agggtttatt gtttgctaac gtccgagcgg atattgaaga atttatgaat agtacatacc
     3601 cagagatgca agcaaatttc aaaaggtatt ttggaaatag acattttacg ccgaaaaaat
     3661 atgtttatat cactacgaaa aagcaaaaat taaatttctt aaaagaataa gggggggcta
     3721 tggataagca attatgggta ttatgtccta tttgcaataa taagacacga actaaagtgc
     3781 gagaagatac agaactgata aattttcctt tgttctgtcc gaagtgcaaa acggaaactt
     3841 taatcaatat aaagcatgga aaagtaacta ttatcaaaga gccagacgca aagacgcaga
     3901 gccgataatt tgtaggttat tatgacttat agattgttgg ctcttatttg ttacctgcgg
     3961 agcagatcag caaatagata atgcagaata gcaaaaaggg aaaacaagaa gctgattact
     4021 tcttgctctc cctgctgttc aagataccgt caatcgtacc ttgaatgatt tttaattcgt
     4081 tatcactcaa taaatcaaga gaggtttcta tctgacggcg agctgtactt tttacgacgt
     4141 tctctgctgg atagaaatat tcatcgaccg atatattgaa catggtaact aaatcatgga
     4201 ataattgaaa actagggtgt gaaccaacat tttcaatatc tgcgatatgg cgttctccat
     4261 agaacacttt atcgcctaaa tcattacgag aaagccctgc tctctcacgg gcttctctga
     4321 ttgccagtcc taaaggtctg aaatcaaaag tttgtgtttc ttttgctttt ctcattttaa
     4381 atcacctagc atgagtttat acttcatgct gtatatttag aatgtgttaa aattgagcga
     4441 atcattcaat tagaaaacga aaaagaatag aatcacaaat cacaagtgat taatcacaaa
     4501 tcacttgtga tttgtgattg ttgatgataa aataagagta agaagaaata gaaagaagtg
     4561 agtggttgtg ggaaatttag gcgcacaaaa agcaaaacga aatgatacac caatcagtgc
     4621 aaaaaaagat attatggggg ataagacggt tcgtgttcgt gctgacttgc accatattat
     4681 aaaaatcgaa acagcaaaga atggcggaaa cgtaaaagaa gttatggata aagccttaga
     4741 agaatatatt cggaaatatt tacctgacaa actttaaaag gagtgaaaat gaaatggcag
     4801 ttacttatga aaaaacattt gaaatagaga tcattaacga attatcggca agcgtttata
     4861 atcgagtatt aaactatgtt ttgaatcatg aattaaataa aaatgactct caattattgg
     4921 aagtcaattt attaaaccaa ttaaagcttg caaaacgtgt aaatcttttt gattattctt
     4981 tagaagaatt acaagccgtt catgagtatt ggcggtcaat gaatcgctat tcaaaacaag
     5041 ttttgaataa agagaaagtg gcttaatatg gcaaatatag tcaattttac tgacaaacaa
     5101 tttgaaaatc gcttaaatga taatttagaa gaattggttc aaggaaaaaa agcggttgaa
     5161 tcgccaaccg cttttttact tggtgggcaa ccagggtcag ggaaaacgag tttgcgaaga
     5221 agatgattga gcaggcagga acaaagtgat aaattcaaat tgtgagggaa aatatagatg
     5281 aatcaaggaa gaattattgt gattacaggc tcaccgggga caggaaaaac aacaactgcg
     5341 tcaattgtcg caaaggaatc agatatggat aaatcagtgc atatgcacac cgatgacttt
     5401 tttcattact taagcaaagg cgcaatacca ccacatttgc cagaatccaa caagcaaaat
     5461 ctggttgtca ttgaagcctt tttagaggct gcaaagcgat atgctcgtgg cggatatgat
     5521 gtaattgtag atgggattgt cgggccatgg tttttggagc catggaaagc tcttgcccaa
     5581 gaagattacg aggtacacta tattgtatta agagcgagta tggaaataag acttagaagc
     5641 aaacttaaga gtgtgttgat agtgcagtat cttaaaattt tgtataatag gaattgaagt
     5701 taaattagat gctaaaaatt tgtaattaag aaggagtgat tacatgaaca aaaatataaa
     5761 atattctcaa aactttttaa cgagtgaaaa agtactcaac caaataataa aacaattgaa
     5821 tttaaaagaa accgataccg tttacgaaat tggaacaggt aaagggcatt taacgacgaa
     5881 actggctaaa ataagtaaac aggtaacgtc tattgaatta gacagtcatc tattcaactt
     5941 atcgtcagaa aaattaaaac tgaatactcg tgtcacttta attcaccaag atattctaca
     6001 gtttcaattc cctaacaaac agaggtataa aattgttggg agtattcctt accatttaag
     6061 cacacaaatt attaaaaaag tggtttttga aagccatgcg tctgacatct atctgattgt
     6121 tgaagaagga ttctacaagc gtaccttgga tattcaccga acactagggt tgctcttgca
     6181 cactcaagtc tcgattcagc aattgcttaa gctgccagcg gaatgctttc atcctaaacc
     6241 aaaagtaaac agtgtcttaa taaaacttac ccgccatacc acagatgttc cagataaata
     6301 ttggaagcta tatacgtact ttgtttcaaa atgggtcaat cgagaatatc gtcaactgtt
     6361 tactaaaaat cagtttcatc aagcaatgaa acacgccaaa gtaaacaatt taagtaccgt
     6421 tacttatgag caagtattgt ctatttttaa tagttatcta ttatttaacg ggaggaaata
     6481 attctatgag tcgcttttgt aaatttggaa agttacacgt tactaaaggg aatgtagata
     6541 aattattagg tatactactg acagcttcca aggagctaaa gaggtcccta gcgcctacgg
     6601 ggaatttgta tcgataaggg gtacaaattc ccactaagcg ctcgggaccc cttgtaggaa
     6661 aatgtcctaa gtgtggcaac aatattgtat taaaaaaatc gttttatggt tgttcaaatt
     6721 atcctgaatg taccttcact ttagctgaac attttagaaa gaaaaaactc accaaaacaa
     6781 atgtaaaaga attactagag ggaaaagaaa ccctggtaaa aggaatcaaa acgaaagata
     6841 gaaagtccta caatgccgtt gtaaaaatcg gagaaaaggg atatattgat tttatctctt
     6901 tttcaaaata agcataaaag ccctttaaag agggctttta tatattaatc acaaatcact
     6961 tatcacaaat cacaagtgat taatcacaaa tcacttgtga tttgtgattc ctaatgatac
     7021 aatattacta tacaaaaaaa gaatggggcg tagttatgga gaaggaagaa ctcaaaatac
     7081 ttgaagaatt aagacgtatt ttaaacagta aaaatgaagc gattgttatc ttaaacaatt
     7141 attttaaagg tggtgttgga aagtcaaaat tatcgactat gtttgcttac ttgacagaca
     7201 aatttaattt aaaagtttta atgatcgata aggacttaca agcaacattg acaaaagact
     7261 tagcaaaaac atttaaggta gaattgccac gtgttaattt ttatgaagga ctgaaaaatg
     7321 gaaacttggc ttcttctatt gttcatttga ctgataattt agacttgatc cctggcacgt
     7381 ttgatttgat gttactgcca aaattaactc gctcatggac ttttgaaaat gaaagtagat
     7441 tgcttgctac tcttttagca cctttaaaaa gtgactatga tctcattatt attgatactg
     7501 taccaacgcc aagcgtttat acaaataatg caatcgtggc aagtgattac gtcatgatcc
     7561 ctttacaagc agaagaagaa agtacaaaca acattcaaaa ctatatttcc tatttgattg
     7621 atttacaaga acagtttaac cctggactag atatgatcgg ttttgttcct tatttagttg
     7681 atacggacag cacaacgata aaatcaaacc tggaagaact gtacaagcaa cataaagaag
     7741 ataacttggt tttccaaaat attatcaagc gaagtaataa agtaagtacc tggtctaaaa
     7801 acggcattac agaacacaaa ggctatgaca aaaaagtttt atctatgtat gagaacgtat
     7861 tttttgaaat gcttgcatat agtatgcagt aataattcaa aagctgttat cgtgtgcggt
     7921 aaataaaaaa aaccgttcct agataataca cttttgtgcg tcttgaaaaa taacgggacg
     7981 gttttggata taaccagaac tgtccttttt tcttaggagt aaataaggca tagctctggt
     8041 taaagggggc tataccatga ttgcatacgg aagaacgttc tgccgttctc aactgaataa
     8101 atatttcagt ccactattac aatcattaca ccctttacaa gaattaaaaa ttcatatcaa
     8161 tagaatttat aaaacagtct gtttgtgtaa ttacacatta tcgggctgtt tttgttttgt
     8221 taaaaatttt tttcaacttt tttcggtttc aacttagcaa atcacacctg tcgttcccta
     8281 tatggtgcgg aaagagggat aaccactttt catatcgtaa cggaaagggg gtgagattga
     8341 tgaaaccatc tgacttccag aaaacagttc aatgccgttt tgaaagttgt ttgaagaaag
     8401 ttgtccgaca tgttgttaag gactatcaga agaaattaaa gcgacgacaa aagggagaaa
     8461 cgcttttttg tgaacttcca gaaatcgttg tagaaaatct ggctgtctgg gacgactatg
     8521 atacggacta tacgattttc aatgtatgtg gtagtgatat tcgtatttgt gatgatgaac
     8581 tggcagaagc cttgaaacat ttgtctgagc gtaatcgaga aaatttgttg atgtattatt
     8641 tcttggaaat gagcgatacc gagattgcaa aaagacaaaa tatttcaaga agtggtgttt
     8701 ttcaaaaccg acacaattca ctagagctta tgaaaaaaat actaaaggag aaatgatagc
     8761 aaatgaaaca cacaatgaag aagccgtcct actacttgct ttcgcaggca atggacgggg
     8821 acgaaaaagc gattgaaaag atactggcat tttatgaccc ttacatatca aagtgctgtc
     8881 tacgaccact ctatgatgaa tacggcaatg tctatattgt tgtagatatg gaattaaagg
     8941 gacttatcag agaagcactt attaaaatga ttttagggtt tgatattgcc ttagaaatcg
     9001 aagaagaata acaagcagta accgcagagc atgatttgtt caatcccctc tttcctgctc
     9061 tgcccctgct tttatatgaa agcaacacgc tttcgccaca gctctttgac aactgaataa
     9121 agcagacaga tacg
//
LOCUS       DAEOTL010000124         9059 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEOTL010000124 DAEOTL010000000
VERSION     DAEOTL010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9059
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.126"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            164..505
                     /locus_tag="KRH82_003585"
     CDS             164..505
                     /locus_tag="KRH82_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBG8656835.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            656..1069
                     /locus_tag="KRH82_003586"
     CDS             656..1069
                     /locus_tag="KRH82_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBG8656836.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1271..1912
                     /locus_tag="KRH82_003587"
     CDS             1271..1912
                     /locus_tag="KRH82_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBG8656837.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1936..3189
                     /locus_tag="KRH82_003588"
     CDS             1936..3189
                     /locus_tag="KRH82_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBG8656838.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3235..3885
                     /locus_tag="KRH82_003589"
     CDS             3235..3885
                     /locus_tag="KRH82_003589"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBG8656839.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNAKEVIQIAENSDIDFKDNNIYLDNEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3936..4532
                     /locus_tag="KRH82_003590"
     CDS             3936..4532
                     /locus_tag="KRH82_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBG8656840.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4545..5384
                     /locus_tag="KRH82_003591"
     CDS             4545..5384
                     /locus_tag="KRH82_003591"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBG8656841.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKRYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5629..6783
                     /locus_tag="KRH82_003592"
     CDS             5629..6783
                     /locus_tag="KRH82_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBG8656842.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNSKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7089..8786
                     /gene="ade"
                     /locus_tag="KRH82_003593"
     CDS             7089..8786
                     /gene="ade"
                     /locus_tag="KRH82_003593"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBG8656843.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKVYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         3715 a          871 c         1583 g         2890 t
ORIGIN      
        1 ctttttaact ttaaaaatta atgttaaaaa ataaacttat acattaatat taataataat
       61 tatttaaata tcttaagtaa atcagtctta catatatttc cgatagatta tattgataaa
      121 aaacactaaa attaaattaa taaaagtact tggagggatg gaaatgaaag aggaaaattt
      181 tattaatgtt gaatacgagg ataaacgttt ttcaattaat agtaaagaag ttttgtacat
      241 agaaaagcaa gagtatgaag taaagattta tactgaaagt ggtaattatg aagttggaga
      301 aaatgctcct tgtataagaa aactattgaa agaagaaaat tttttcaaat gcagtaatag
      361 ttatattgta aatctagaca agtgtgaatt ttatctcagc aataattgta tttttgtgaa
      421 taataatttt ataagaattt taggttcaga aagaaaaaag aaattaaaaa agaaattaga
      481 aaaattatat gattatgaag attaatattg ggaggctgta ttttatacag cctctttatt
      541 tattgattgt attattaata aattttaaat tatgataaaa tataaaacaa gtaacttatt
      601 tcagaataaa atacttttta aaagaaaggg acgagatatg ggagattata ataaaatgat
      661 tgaattaaag aataacttag gtatcagtga aagaaagtta aaatatcctt gtatctataa
      721 acattttaaa ggaaaatatt atgctacaat gggtcttagc aaggctattg atgatataga
      781 aaacatatgt gaaatatatg gtaaagaaaa tttaatccaa aacagaaata aatataaatt
      841 agttattaga catactgaaa gagaagaaga tatctatgtt tatagggatt tagatggaaa
      901 cttttatcat aaaaaagaag aagatactaa tgatttagtt ttatacaaga ccttatatga
      961 tgatacagga atatttgcaa gacctttgga tatgttttta gaaaaagtag atacagataa
     1021 gtatgtcaat tcaattcaag aatacagatt tgaagaagta tataaataat atgagagaaa
     1081 tatgcttata aatttagaaa aattctttaa cagtacaata atttgcagaa atacaaatga
     1141 gatttattgt aaataatatg ttagattaga ttataaaata gaaacaaagt aaagtattat
     1201 atgatataat taagttttga gaagtgataa tttatattta ataaaaaata ggcatatatt
     1261 aggaggacat atgggaaata ctttttatat agtaagacat ggacaaacgg attggaatat
     1321 attgggaaaa acacaaggtc atggtaattc tgaccttacg cctcaaggta tagaacaggc
     1381 aaaagaactt tctgaagata ttggcaagta ttcaattgat tatattttta gtagcgacct
     1441 tgggagagca atgcaaacag ctcaaatttt aggagataag ctcaatattg aagttcaaaa
     1501 aactgaggca cttagagaaa tgggattcgg agtttgggaa ggccttttaa taaaagaaat
     1561 tcaaaaagat tattcagata tatatgcaac atggagaaat gaaccacact tagtaaatat
     1621 accagaaggc gaaactctta agattataaa ggaaagagta gatgctttta taaaggaact
     1681 aaatgaaaaa tatgataata aaaatataat tcttgttaca cattcaatta cattgagggt
     1741 tatgttgttg tcatttttag aatcaggtat ggaaaatata tatagaatta agcaagataa
     1801 tactgcttta aatatagtag aatttaaaga ttatggacct gttatagtaa aaatgaatga
     1861 tacaagtcat ataaaaaatc atgtaaagat aaataattct gcactggagt aggaatcaat
     1921 tataaggaga aatttatgag taaagttata gtagttggtg gaggagcttc tggaatgatg
     1981 gcagctttgt cagcttcaaa aaacaataat gaagtaatat tagttgagag aaatggagaa
     2041 ttaggaagaa aacttagggc aactggtggc ggtagatgca attttaccaa taatagagag
     2101 atagaagatt tttttgataa agttgtcagt aataaaaaat ttctctatag tagtttctat
     2161 acatttacaa ataaagacct tatttcgtat tttgaaagta gaaatttgga atataagatt
     2221 gaagaagaaa atgaccacaa agtatacact aaaaatgata aatctataga agtaatagaa
     2281 gtattaaata aagatttact caatcacaat gtaaagataa tgtataataa gaaagttata
     2341 gatattataa ctgaagaaat tgctctaaaa gatgattcta ataaggacaa gtcaaagtat
     2401 ctaataaaag ggattatttt agataatgga gataaaatac taggagacaa ggttattata
     2461 tcaactggag gagtgagtta ttcaaagacg ggttcagatg gttcaatgta taagattctt
     2521 aaaaagcatg gacatacatt aaacaaacta tatcctgctt tagttccact tacaatagag
     2581 gaaaaatgga ttaaagattt acaaggaata tccatgaaga atgtggaaat atcttgtaag
     2641 attaagaaaa ggaaaatatc aaaatctgga gacatgctat ttgcccattt tgggataaca
     2701 gggccttgtg ttcttataat gtcttcttat attaacaaga ttattgaaaa ggaaaaggta
     2761 gaattaaata tagatttctt accaaattta agtactgatg aaatctctag tataatcaga
     2821 gcatttccaa ataaaaatgt tctaaataat cttaagcaaa tactacctca aaatttctta
     2881 aaagagattt tttctctatt atctttagtt gataaaaagg caagtgattt gtctaaggca
     2941 gatgaaatta gaattattga gtatataaaa aatatgaagc taacttgtaa tgggactaca
     3001 ggtataaaca ctggtatggt tacttctggt ggtatttcag ttaaagaaat taattcttct
     3061 actatggaat ctaaattagt taagaactta ttttttacag gtgaagtaat tgatatagat
     3121 gcagaaactg gtggatataa tttacaaata gcattttcaa ctggatatct tgcgggtata
     3181 agtgtataaa tataattttt taataattaa atatgaataa atagaggtgt atatatgggt
     3241 aatttagtta tagctgtaga tggtccagca ggagctggaa aaagtacaat agccaagata
     3301 gtagcaaaaa agctaaatat aaattatata gatacaggtg ctatgtacag agcagttact
     3361 tataagtgtt taaaaagtgg tattgatgtc aataatgcaa aagaagttat tcaaatagct
     3421 gaaaattcgg atatagattt taaagataac aatatatatt tggacaacga agttataaat
     3481 gaagaaataa gaacaataga agtaagcaat aatgtttcta atgtagcaaa aataaaagaa
     3541 gtaagacagt tgatggttga agttcaacga aaaataggaa tgaaaagttc agtaatacta
     3601 gatggtagag atataggttc atatgttttc ccagatgcag attacaaatt ctttttagta
     3661 gctactccag aagaaagagg aaatagacgc tataaagaac tttgtaataa aggatataat
     3721 actactttag aagaagtaat tgaggatata ataagacgag atgaaattga ttcaaataga
     3781 gaatttgcac cattggtaaa agctaatgat gcactagaaa tagatactac aggaaaaact
     3841 atagaagaag ttgtagaaga agttgtatct aaaataaatc tttagttttt tatgcatcat
     3901 aatgaaaata aatgtagtgt tgaagggaga taaacgtgaa tttttataga tttgtaataa
     3961 atatttttaa gggtttttct aaaatatttt ttaaatatga agttataggt gcagaaaata
     4021 ttccagatag aggaaatata gtaatagcat caaatcataa atcgaatctt gaccctatat
     4081 tcttggctgc tgccatagaa aatagagaaa tagctgcaat tgcaaagaaa gaattgttta
     4141 aagtaaaacc cttgggattt atattaaaaa aattgcatgt tatgcctata aatagagaaa
     4201 aaccagatgt atctacaata aaaactattt taaggtcagt tagagatggt tatgtattag
     4261 gaatatttcc agagggtact agaataaaag gagattcttt tggtaaggct aaggcaggtc
     4321 tttctgtatt tacaataaaa agtaaatcta aagttgttcc agtatcaata atatctaaat
     4381 ataaactttt tagtaaagta attgtatata ttggagaacc aatatcattt gaagaacatt
     4441 ttaaggaaaa attgagtaat gatgaccatg aaaggatatc acaagagatt ttagaagtga
     4501 taaaacaaaa ttactttaaa tattcaaaat aagggggtaa agttatgaac ataaaaatag
     4561 caaaaaatgc tggcttttgt tttggagtaa aaagagcaat gaaaatggca tgggatgaag
     4621 ttgaaaaaaa tgattctggc atatatgctt taggtcctct tattcataac aagcaagcag
     4681 tagcaaaata tgaagaaaaa ggtcttaaga ctgtgaatga aattgataca ataccaaatc
     4741 atgaaaatat gataataagg tctcatggag ttcctgaaaa tatatataag gaagccaaag
     4801 ataaaaaatt aaaaattgtg gatactacat gtccatttgt aaagaaaata catacagtag
     4861 taagtgaata tcataataaa ggctatgaaa taatagttat tggagatatg aagcatccag
     4921 aagttatagg tataaatgga tggtgtgaaa attcagctat aataataaag accttagaac
     4981 aaatggaaaa tatggaattt gataactcca aaagatattg tcttgttgca cagactacaa
     5041 taaatccaga gttgtatata agtatagtta ataaactatc agataaatta gaagaaatag
     5101 tatttaatga tacaatttgt tcagctacaa aaacaagaca agaatcagct aaagagttag
     5161 ctaaagaagt tgattgtatg atagttatag gaggtaaaca cagttcaaat actcaaaagt
     5221 tagtaaaggt ttgtgaagac ttagtaccaa cttttgcaat agagactaaa gatgaattgg
     5281 atgtaaatac gcttaaaaaa tataaaaatt tgggtattac agcaggggca tctacaccta
     5341 attggataat agaagaagtt gtaacattcc ttgaaaattt ataatttgat aggtaataaa
     5401 aataggtgga cattgttata atttatcata atatccacct ttgatttcat attacatgtg
     5461 gtaaatagat aacctaatat caaaaagtgt gtatcttaag atgaaaaact aatagtataa
     5521 gatgcgcact ttttaatatt agaaattcaa aagaaatgtt gatattgatt atcaatagaa
     5581 aataaaatat aatataattg ttgcaaaatt agtctaggag gtaaattaat ggaaatgttg
     5641 atatctgctt ctgaagaggc gtttttacat gtaggttcta tgattggatt ttttattttg
     5701 ttatttggat atattaatta taaaactagt ggaaatttta ctaatatcat atcaaaaaac
     5761 agaaaatttc aaccattaat aggtgcttta attggagcta taccaggttg tggcggaagc
     5821 ttggcaataa tgccattgta tataaatgga aaattaagct ttggagcaat aattgcaagt
     5881 ttaatagcta gtatgggaga tgcagcattt gtacttattt catcaaatat taaaatgtat
     5941 ttttttgtca ctatagttag tacaattaca ggaataataa ctggacaatt agtggattac
     6001 tttaaactag aagaaaaatt agggttaaaa aaccgtagaa aatcagataa atacgatata
     6061 agtaaaaata actctaaaga aaataaagaa caacataatc atgatgaaat aattttagac
     6121 actctagcta aatctcatgg aaatacaaat agacttgcat ttataataac acatggaaag
     6181 ggatataaaa tttatatagg aattatagta atcggtttta tatttatgtc acttgctcac
     6241 tctggactta atcttcctat aattgagaag ttacattcat tggaagaggt aatagcagtg
     6301 attggaatat tattttcaat aatttatatg tggtgtttta aaaaggtatt taaaaattct
     6361 aatcaaaaag aggaagaaaa taaaaagatt tctttgcgag aaatgcttat ccattctgtt
     6421 ggagaaatat catttgtaat tacatggatt tttattgcat atcttattta cgatttgata
     6481 atattaattt taggtggaga tgaatactta gttaaattag tattatcaac aggtgtaata
     6541 agtgtattta taggtgcagg tcttggactt attccaggtt gtgggataca aattgtgctt
     6601 atgtcatttt atttgaaggg aactatacca cttggtgcag tgatagccaa ctctatttct
     6661 caagatggag atgcactttt cccactttta gcaatggata aaaaatcttc tttatgggct
     6721 atgattatta ctactatacc agcaatactt gtaggtatga tagtttatgc atttttaggt
     6781 taaatataat tatgaataaa gaagtattaa aaaaataata aagcacataa atttatttat
     6841 aagaatagtg aagattaaat ataaaaataa aaaattcaat atgaattaaa ttattgctta
     6901 aatattaatg agaacatggg agataatatt attcctcatg ttctctctat ttaattaaag
     6961 gaattatgga acaaatttca agtgatactt tctatcaaaa ctcatatata atatatatta
     7021 ataaattaaa ctataatacg taatacagcc agtatattga tataaaaaac ttaggaggag
     7081 ttgtaaaaat gggtaattta aaaagacagt gtgatgtttc aagtggaaga gaaaaagctg
     7141 acattgtact aaaaaatggg acaatcataa atgtatttac agaagagtta ataacaggag
     7201 atgtagcaat agtaggagac actatcgttg gcattggcga ttacaagggc aatgtagaaa
     7261 ttgattgtag taacaaatat atatcacctg gctttattga tgcacatatg catattgaat
     7321 ctacaatggt aatgccaatt gaattatcga aaaaattatt aaaatcaggt acgacaacta
     7381 tcatagccga cccacatgag ttggtcaatg taaaaggagc tagtgcaata gattttttat
     7441 tagaatcgac aaaagatata ccacttaatg tatatattat ggtgccttca tccgtacctg
     7501 caacaagttt tgaaactaat ggagttggta aatttagtgc aaaagacatg gagagttatg
     7561 taaataatcc tagaatttta ggtttaggag aggtaatgtg ttttaatgat gttataaatt
     7621 ctgaaaatga aatcttggat aaactagagc tttttaaaaa taaagttgta gatggacatg
     7681 cacctaatat aaatggtaaa tcacttcaga catatgtatg tgcaggaata gaaaatgacc
     7741 atgaatgtat aacttttgat gaagtatatg aaaaattgag agcaggatta aaaattttaa
     7801 taagagaagg aagcgcagca aaaaatttaa agtctatagt aagtggtatg ctaaagcata
     7861 acttgccaat tgaagaattt atgttttgca cagatgataa gcacttagat gatatagaaa
     7921 aacaaggtca cataagatgg aatataaaat gtgcgattga tttaggtatg gaacctgtta
     7981 gggctataaa agttgcaact tataattctg caaaagcata tgggttaagg aaaattggag
     8041 caataggtgc gggttataag gcagatattg ttgtattgaa tgatttagac aaaatggaag
     8101 tggatagtgt atataaagat ggtaatttgg taaacgaaga gatgttttct aattacaatt
     8161 atgagattaa agataaagaa ttgcttaata cagtcaagtt taaatatatt aataaagaaa
     8221 aaatacagtt aaaagtaagt gaaaaaaatt atgtaatgga gattgtacct tatcaaattt
     8281 tgacaaataa ggtatatgaa tctttaccat gtgcagatgg atattttgtt ccaaataaag
     8341 agtattcaaa actttgtgtt gttgagagac atagaatgac tggaaatgta gcaattgctc
     8401 cattaaaagg atttggcata aaaaatggag caattgctac tactgtggcc catgattctc
     8461 ataatattat agttgcaggg gataatgatg atgatattct agtagctata aattacttaa
     8521 aggaaataca aggtggttat gtaattgtat caaatggaaa agttcttgca cacctaagtc
     8581 ttcaagtagc tggattaatt agtactttta cagctgaaga agtacaagaa attactgata
     8641 atatgttgga gatagcaaga aaaatgggag ttccagagta tgtagaccct tttattacac
     8701 tttcttttat ggcacttcca gttgttccac aaataagact tacagattta ggtctatttg
     8761 atgttgagga atttaaattt atatagataa tataaaagta ataataaatg aggctttctc
     8821 aaaataggga taagtctctt tttattgttg aaatgatgaa aatatatttg atttcataca
     8881 aaaaagagca tctcatgaac taaaaatttt atttttagat atccttattt taattaatct
     8941 atcatttaac cttgttttaa gcatagatat cttaataaaa ctattttcag tctattttaa
     9001 catataaata catgaaaatt atatatttat gaaactttat acataaaaaa taaaatatt
//
LOCUS       DAEOTL010000125         9005 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEOTL010000125 DAEOTL010000000
VERSION     DAEOTL010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9005
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.127"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            94..660
                     /locus_tag="KRH82_003594"
     CDS             94..660
                     /locus_tag="KRH82_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBG8656844.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            965..1426
                     /locus_tag="KRH82_003595"
     CDS             965..1426
                     /locus_tag="KRH82_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656845.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1494..3740
                     /locus_tag="KRH82_003596"
     CDS             1494..3740
                     /locus_tag="KRH82_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656846.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3733..5565
                     /locus_tag="KRH82_003597"
     CDS             3733..5565
                     /locus_tag="KRH82_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656847.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6284..7561
                     /gene="hflX"
                     /locus_tag="KRH82_003598"
     CDS             6284..7561
                     /gene="hflX"
                     /locus_tag="KRH82_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBG8656848.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7794..8291
                     /locus_tag="KRH82_003599"
     CDS             7794..8291
                     /locus_tag="KRH82_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8656849.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVEEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8341..8865
                     /locus_tag="KRH82_003600"
     CDS             8341..8865
                     /locus_tag="KRH82_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBG8656850.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
BASE COUNT         3573 a          898 c         1623 g         2911 t
ORIGIN      
        1 atttaataaa tataaattaa attatatgtg tatatattgt actttaatag tgatataata
       61 ataaaaaaat ttttaaagag ggtgatatta catatgagaa aacttgaaga gatattagaa
      121 tataataaat catttgtaga gaacaaagaa tatgaacaat atgtgacatc aaaacatcca
      181 aataaaaaaa tagtagtctt atcttgtatg gatacaagat taactgagct tttgcctaag
      241 gctatgaatt tgaaaaatgg agatgtgaaa ctaataaaaa atgcaggagc tactataatg
      301 catccttttg gaagtattat gagaagtgtt ttagttgcaa tttacgaatt tgatgtagat
      361 gaggttatgg ttgtagggca tcatggatgt ggtatgtgta atgttgatac ggataagtta
      421 cttggtaaaa ttttagatag aggaatatct aatgatgtaa tacttacact tcgtagtgct
      481 ggaattgata caaaacaatg gttacatgga ttcgattctg cagaagaatc tgtaaaagat
      541 agtattgatt taataaaagg gcatccttta attccagatg gtattattgt acatggtcta
      601 attatatcac ctgaaactgg gaagttagat gttgttgtaa atggatatga agataagtag
      661 agtatcataa tgttatataa tcaagatact gttgaatatg atgttgtttc aaaatttatt
      721 ttgggacaac ttttttattt aaaaatatat gaaaaggttt attttaagct ttacaataaa
      781 aaatataagt agctgactaa ttaaaaatct tactattatt tattaaaatt ataactatat
      841 gatataaaaa tatttaataa atgaaattta tatgaatttt ttataaatat attgaaaaaa
      901 tgcatgcagt atagtaaaat aatacttagc tgactaagta atataaaaaa taaggagggc
      961 aagtatgaat agcaattctg aagaaaaatt aaatgatgtt ttcttgcaat taatgcgaat
     1021 atattttata agaactcatt tttattttga taaattaggc ttatatcatg gtcaacccca
     1081 aatacttttt tctttaaaga tgaaagatgg gcaaagtcaa aaagaattag cagataaaag
     1141 gaaagtaaaa gcatctacaa ctacagttat gataaagagg atggaaaaag ctggacttgt
     1201 ggaaagaaaa caagatgaaa aggaccaaag agtatctagg atttttttga cagacaaagg
     1261 tttagaaata tgtaataaag ttgaagaatt taacaaggaa ttggaaagag agtttttttt
     1321 aggatttagt gaagaagaaa aaatagtact tagaagactt ctaatgcaag tacgagataa
     1381 tttaaaagca ggatgtcata agcatgaaga tgaaaaatat ttttaaagtt taaaataatg
     1441 tttttcaatt taatgttatt agactaatta atattacaga agggaagaaa tgtatgttta
     1501 aattaattaa atatttaaag aaatcggcat tatcaatagt aataatagtc tgtctattgg
     1561 taattcaagc ggtatgtgac ctttctttac cagaatacac atccaatata gtaaatgtag
     1621 gtatacaaca aggtggagta gaaaactctg ttccatctgt gattagagag agtgaattaa
     1681 ataaaattac tttatttatg gataaaagta gtaaggataa agtactagat aattatactt
     1741 tgctgaataa aaaggattat gttaagtata aagataagta cccaggtcta aaagatgaat
     1801 ctctttatga gttaaatact aaagacaaag acactataga tgatttaaat gttatttttg
     1861 gtaaagctat tttaatagta tcagggcttg agggcgatag taaagaggta aaagctatga
     1921 aagctcagtt aatgagtaaa cttccaccac aagctactca aagtggagat gttgatatat
     1981 ttaaattgtt atcagcaatg ccaaaggaac agttagatac attgactaaa gagatgagca
     2041 aaggctttga aagtatgcca gagagtatga taacacaaag ctctgtttca tatgtaaggt
     2101 cagaatatga gaaaataggt attgatacag aaaaaactca aaataattat atattattta
     2161 ctggtgctaa aatgcttggt atagcaatga ttagtatggt agctacaata acagtaggat
     2221 ttttagcagc aagagtagcc gcaagtgtag gtagaaattt aagaagtgga gtatttagaa
     2281 aagttatgtc attttcaaat actgaaatga atgaattttc tacagcttca ttaattactc
     2341 gtagtacaaa tgatattcaa cagatacaaa tgttgatggt tatgttgctt agaatagtat
     2401 tctatgcacc tataatggct ataggtggag tgataaaggt tttaaacaca aatacttcaa
     2461 tggcctggat tatagcagta gcagtagttg ctatcttatc attaattgta gtgttattct
     2521 cagtggttat gcctaagttt aaactggttc aaaagcttgt tgataagtta aacttagtaa
     2581 gccgtgaaat aattactggt attccagtta tcagagcttt tagtactgaa aaacatgaag
     2641 aagaaagatt tgataaagca aataaaaatt taactaaaac aaatcttttt gtaaatagag
     2701 ttatgacatg tatgatgcct gctatgatgc ttataatgaa ccttatcaca gttcttatag
     2761 tttggagagg tgcatacagt gttgattctg gagcaatgca agttggagat atgatggcat
     2821 ttatacaata tacaatgcaa ataataatgt cattcttaat gatatcaatg gtatctatta
     2881 tgcttccaag agcatccgtt tcagctacac gtatagatga agtattagtg tcagatataa
     2941 gcataaaaga cccagaaaaa tcagaggcac aagagtttaa ggaagataaa aagggtcttg
     3001 ttgaatttaa aaatgtttcg ttcatgtatc cagacgcaga agaacctata ttaacaaata
     3061 tatcttttac agcaaagcca ggagaaacaa ctgcctttat aggaagtact ggtagtggta
     3121 agtcaactct tataaattta attcctcgtt tctttgatgt tactgaagga gaaatattac
     3181 ttggtggagt taatataaaa aatgtttctc aacatgattt aagggaaaaa attggatatg
     3241 tacctcaaaa gggagtattg ttttctggta ctatagaatc caacttaaaa tatggtagaa
     3301 aagacgcaac agatgaagaa atgagaacag cagctgaaat agctcaagct acagaattta
     3361 tagattctaa accggaagct tttaaaactg aaatttctca aggtggaaca aatgtatctg
     3421 gaggtcaaaa acaaagactt tctattgcaa gagcaatagc aaaaaatcca gaagtttata
     3481 tatttgatga tagtttttca gcacttgact taaaaactga tgcagctctt cgtaaggctt
     3541 taaaatcaaa aactgctgaa agtacagttc taatagttgc acaaagaatt agtactatct
     3601 taaatgcaga acagataatt gttttaaatg agggagaaat agttggaata ggaacacata
     3661 aagagcttct aaaaaattgc gaagtttatg agcaaatagc tttatcacaa ctttcaaagg
     3721 aggagctagc taatgagtag aatgggaaga ggtcctatgg gaaaatctat gggagcagga
     3781 caaaaagcaa atgactttaa agggactatg cgaaaactaa ttgcatattt atctaaattt
     3841 aaaatatcaa taattctagt aattgtattt gctattggta gtgcgtcgtt ttctatagta
     3901 ggtccaaaaa ttttaggaaa ggcaactaca aagatatttg aagggctagt gagtaaagtt
     3961 tctggaggaa acgtaggtat agattttaat gcaattggaa aaatcttaac ctttttactt
     4021 ttcctttatt tgataagtgc actgttctct tttatacaag gatttataat gagtggaatt
     4081 tctcaaaaag tatcctataa tttaagaaaa gagatttcag caaaattgga tagattgcca
     4141 atgaagtatt ttgatactaa gacacatggt gaaatattat cgagaattac gaatgatata
     4201 gatactttaa atcaaagttt aaatcaaagt atgacacagc ttataacatc agtaacaact
     4261 atgataggtg ttttgataat gatgttatct ataagtggaa ttatgacatt agtggcagtt
     4321 ttaatattac caatatcaat gtttgtaatt tcaagaataa taaagaaatc acaaaaatac
     4381 tttagatatc aacaagaata tttaggaaat gtaaatggtc aagttgaaga aacttacagt
     4441 ggccaaacaa tagtaaaagc atttaatcgt gaagatgaag taattgagga gtttgataaa
     4501 ttaaatgata gcctgtataa ttcagcgtgg aaatctcaat ttttatcagg tataatgcaa
     4561 ccacttatga tgtttattgg aaacttggga tatgtaatgg tatcaatctt aggaggttgg
     4621 cttgcaatta agaaaacaat tgaggttggt gacatacagt catttataca atatgtaaga
     4681 aactttacac agccaatgac tcagattgca caggttgcca atttattgca atcaacagca
     4741 gcagcttctg aaagagtatt tgagttttta gaagaggaag aagaagtcca aattgttgaa
     4801 aatgcagttt caatagatgg tttagaaggt aaaattgatt ttgaaaatgt caactttgga
     4861 tataacccaa acaagactat aataaatgat ttctcagtaa atgttaaacc tggtcaaaaa
     4921 gttgctattg ttggacctac aggagcaggt aaaactacaa tagttaaact gttaatgaga
     4981 ttttatgatg ttaatagcgg ttcaatactg attgatggtc ataatattaa agattttaat
     5041 cgtagtgagc ttagagaaat gtttggtatg gttcttcaag atacatggtt atttagtggt
     5101 tcaattatgg aaaatataag atatggtaag ttgaatgcta cagatgaaga agttatagag
     5161 gctgctaaat ctgcacatgt tcatagattt attaagacat taccagatgg atataagatg
     5221 aaattaaatg aagaagcaag taatgtttct caaggtcaaa aacaattatt gactatagct
     5281 cgtgctattt tagctgatcc taaaatttta atattagatg aagctacaag ttctgtcgat
     5341 actagaacag aagtattgat tcaaaaagct atggataatc ttatggaagg tagaacaagt
     5401 tttgttatag cccacagatt atcaactata cgtgatgctg atatgattct tgtaatgaat
     5461 gaaggagata tagttgaaca aggaaatcat gaggaacttc taaagaaagg cggattctat
     5521 gccaatcttt acaattctca atttgaagaa gatgaagcaa tgtaacaaaa aactatctta
     5581 gcatagacat gtaattaata agataaaata aatgagggtg ccttaaaatg aactttttaa
     5641 ttcataaggc actcttttgt gtatgaaata aaatgtattt ttatcatttt aacaatgaaa
     5701 aagaggattc tctatatttt gagatagcca cataatttta tgtctttaca aagtgtttat
     5761 tttattataa tatgtagtaa ggaaaatgtt ggaggtgatt atcaaaatgt atatttaatt
     5821 ttattcttta aattttatta taaatagaat ttaattttaa tagttgatga ttatattgaa
     5881 gtatatgttt ttattacttt tattaatcat gcaaataact acttaaattt aagaataggg
     5941 ttaaatataa aatgataatt acatataagt taattaaact aatgtatttt taatatatat
     6001 ttagaatttt aatccttctt atgatataag tagcttgttt tgtattactt agatttgtaa
     6061 ggagtttttt tattgaaaaa actgcataat atatttggga ggaggtgtaa gaaagtgatt
     6121 ttttatataa gattgagaaa ataatgcacg attatggtta ttataatagt aaataagaag
     6181 tgtcatttaa ggataagata aaaagcaaaa ttcttgatga atttaattat agagccataa
     6241 tctcgtgcta tagattaaat aaaaaatagc agataaggag aatatggata tggcgaaaaa
     6301 aggaataaca gtaggattaa acataaataa taaatctgag gactttaatg aactaatgat
     6361 tgaacttgaa aacttatgtt cagcatgtga tattgatgtt gtagggagta taactcaaaa
     6421 tgcaaagcag gttaatagag cattttacat tgggacaggt aaagttgagg aaatattaaa
     6481 cttaataaag aaagaaaata tagagatagt tatattttac aatgaacttt ctacatcaca
     6541 actaaaaaat cttgaagaaa agcttaattg tgaaattata gatagaacgg cattgatact
     6601 tgatatattt gcacaaaggg caaaaactag agaagctaaa cttcaagtag aagtagcaag
     6661 tttaaaatat atgttaccaa gacttatagg ttcaaatgaa aatttaggac gtcaaagtgg
     6721 tggagttggt actaaaaata gaggttctgg tgagaaaaaa ttagaacttg accgtagaag
     6781 aatagaagaa aagataacat ctttaaatag ggagttggat gatttaaaat tccaaagaga
     6841 aactcaaaga agtatgagaa gaaaatcaaa tcttccaaat gtagctctag tcgggtatac
     6901 aaatgctggt aaatcttcaa taatgaataa actagtagat atatttaaaa actctgaaga
     6961 aaagaaagtg tttgagaaaa acatgttatt tgctacactt gaaacttctg tcagaaatat
     7021 agttcttgca aataacaaag aatttttatt atctgatact gttggttttg taagtaatct
     7081 accacatgac ttagtaaaag catttaggtc aacattagaa gaagcatgtg aggcagacgt
     7141 actgttacat gttattgata tttcaaatcc aagctataaa agtcatatta aagtgacaga
     7201 agatacttta aaacaaatag gtgcagatgg tatacctatg atacatgtgt ataataaaat
     7261 tgatttaata gatgtagaag tattggatag aattttagat agtatcgata aagaaggtat
     7321 atttgtttca gttaaaaaag atataaatat agataaaatg ataaaatgta tttgtgatag
     7381 catatttaaa gattatgtaa gatgtaagtt cttaattcca tatgataaag gtcatgtagt
     7441 ttcttatttt aacgaaaata cgagcattat aaatacagaa tacagagaag atggagctat
     7501 tttagatgta gaatgtagca atatagaata taataagtat aaaaagtatg ctttagagta
     7561 aattttgaaa aacttattat agcctaaaat atatttaatt tataatttat tataaattga
     7621 ttgtaaatat gattttatga aacggtatag ccataatgct atgccgtttt gccatttata
     7681 ataaaaataa atttattgac acaatagtaa ctaattacta taatataaag taactaatta
     7741 ctatttaaaa ttatcaaaaa attaaaatct aagataaaga gaagtgtata ataatggatg
     7801 cagaaagttt aatgaaaaaa tatatggtag atgatgatag tagaaaacaa gctatatttg
     7861 caagtatatt tgtaatgcaa aataaacttc aaactacatg tgataaatta gacccagaat
     7921 taacaatgaa acaatggtta cttttagcta ttgcggactc tgtagatgaa actcttacat
     7981 taaccaaact tggagaatta atggggtgtt caagacaaaa tgtaaaaaaa ctagctattg
     8041 ctttagaaaa gaaaggtttt atagaaattg agcaaaatga aaaagattca agagctatct
     8101 gtcttgtgac aaaagataga gtggaagagt attctaaaaa agtaagaggt atgcaggaaa
     8161 aagtattaca gcttttattt gaagatttta cagagaaaga agtggaacag ttattttttg
     8221 gaattatgaa attaagtata ggaattgaaa atgtgaaaaa ttatgtagaa aataatgacg
     8281 ttggagaata agcaagtatc aaatcaactt tgtatgacat cagagagggg ggtaatttat
     8341 atgaaaaatg tagtagtgat ttataagagt aagtatggtt caacaaaaaa atatgctaaa
     8401 tggctttcag aattattgtc ttgtgatatt tttgaaacta agaatattaa tatagaaaag
     8461 gttatgaagt atgatacgat tattttagga ggaggtcttt atgcttgtaa tatagcggga
     8521 atttctttct taaaaaaaaa ttataaagaa ttgcagaaaa aaaatttagt agtatttggc
     8581 gtaggagctg ctccatatga tgatgaagta ataaagaaat taagagaagt aaattttaag
     8641 gatgaattaa acaaaattcc ttgcttttat tgtcgtgggg catgggatga gacaaaaatg
     8701 tcttttatag attatactct ttgtagtttt tttaaaaaat ctatagctaa aaaagaacgt
     8761 caaggtctta aaccagcaga agcaccttta ttgtctggag aagcatttga ttggtgtaat
     8821 aaagaaaatt taactccaat acttgattat ataagagaac tttaagaggt atatatttat
     8881 aattatttat tatctaaagt tagatttcat agaaacttac tagacattat ttataaaata
     8941 atattattaa agatggataa tttaattttt tcaataaggt tataatttta aaaaatgttt
     9001 atttt
//
LOCUS       DAEOTL010000126         8998 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEOTL010000126 DAEOTL010000000
VERSION     DAEOTL010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8998
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.128"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            235..1557
                     /locus_tag="KRH82_003601"
     CDS             235..1557
                     /locus_tag="KRH82_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBG8656851.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            1854..3215
                     /locus_tag="KRH82_003602"
     CDS             1854..3215
                     /locus_tag="KRH82_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBG8656852.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            3288..4682
                     /locus_tag="KRH82_003603"
     CDS             3288..4682
                     /locus_tag="KRH82_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBG8656853.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            4744..5214
                     /locus_tag="KRH82_003604"
     CDS             4744..5214
                     /locus_tag="KRH82_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBG8656854.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            5217..7433
                     /locus_tag="KRH82_003605"
     CDS             5217..7433
                     /locus_tag="KRH82_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBG8656855.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            7516..8187
                     /locus_tag="KRH82_003606"
     CDS             7516..8187
                     /locus_tag="KRH82_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8656856.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            8550..>8998
                     /locus_tag="KRH82_003607"
     CDS             8550..>8998
                     /locus_tag="KRH82_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="HBG8656857.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGS"
BASE COUNT         3367 a         1057 c         1809 g         2765 t
ORIGIN      
        1 aaatttaaaa gaatttaaaa aaataaatgc tttaataaat tatcaaatac taacaaatat
       61 aataaaaatt atatatgtaa aacaattatg ttaaaaaatt ggcattataa ttgcttcata
      121 ttaaattgag atgacaaaat aaaaaaagaa aggatgttgt gtgagataat aataactgtc
      181 attaaaaaat agttgggagt gataaccttg agtaaatatc aaaagaatgt ttctatgttt
      241 gatattgatg gaaggccacc aattttaaag tgtttgccac tatcaatgca acatatacta
      301 gcaatgatag ttggaactgt tacagtacct atagtcgtag gaggagctgt gggtgttagc
      361 cctacacaaa taacactttt agtgcaatat gcattaataa tagctggtat atcaacactt
      421 atacaactat atccaatagg aaatattggt tcaagattgc ctataatttt tggagttggt
      481 tttacttatg taccaacact tgtagcagtc ggaggaaatt atggattagc aagcattttg
      541 ggtgcacaat taataggggg agtggctaca gtattaatag ggatattcat aaaaaagata
      601 agaaaatttt ttccgaatat agttgcagga acagtggttt ttacaattgg attatctttg
      661 tatcctatag caataaatta tatggcaggt ggtgtaaata gtcctactta tgcctctatg
      721 caaaactggg cagtagcggc tataacatta gtggtagtta taggtcttag tcaatttgca
      781 aaaggatatg caaaattggc agcaatattt ttgggaatta tagttggata ttgtgtatct
      841 ttagttctgg gtataataaa ttttgaccct attagagagg caacttggtt tgcgatacct
      901 aaaccgcttg aatttgggat ggaatttgat atgcctgtaa taatctcagt agtaattgta
      961 agtataatca atgctgttca agcaattgga gatttatcag ctactacaat gggaggcatg
     1021 gataggaata tcacagataa ggaattatca agtggagtaa taggaagtgg aatttgtact
     1081 atgataggag ctttgtttgg aggtttacca ccatcatcat atagccaaaa cgtggggatg
     1141 gtagctatga acaaagtaat aagtagattt gtgcttggaa tagctggtat atttatgtta
     1201 ttgtcggggt ttgtgcctaa atttggtgca ttaatgacta ctataccata ttctgtttta
     1261 ggaggagcta caatatctat atttagtatg ataacaatga caggtataaa gttaattatt
     1321 acagaagagt tgtcatcaag aaatattacc attgttggtt tggcaattgc cttaggcatg
     1381 ggaataacat cagtaccagc agcccaagag gcatttcctt catttgtaaa gttagtattt
     1441 ggagaatctc caatagtaat tgcaacattg gttgcattcg ttttaaatct aataatacca
     1501 aataaaagtc tagaggatga ggctaaagaa agagctgtta tggaagagac taattaagat
     1561 ataataattt aaaagaattg tttaaattat ttagtatgag attgttagat tatttttgat
     1621 agctattcat tttaataaaa aatttaacaa ataaatatat accaggcaat taatgttcat
     1681 ttaagttgaa aatcggggag ggaatattta gaaatttgtt aattttttat aaaaatagct
     1741 cagtttagct gtgtttatcg gttgagcaat aaattcatgg tcataaaaat atttatagaa
     1801 aataattata aaaatattta gtcaagatat ttatgtatgg gaggatttat tttatgaaaa
     1861 cacgtaatac ttcaaaatat gatgtcgatg ggataccacc actaaaggaa tcaatacctt
     1921 tggccttaca acatctgtta gcaatgatag taggaaatat ggtacctgcg atattaatag
     1981 caaacgtggt aggacttaac caggggcaag caacaatgtt gattcagggt tctatgttag
     2041 cagcaggttt agcaacgttt ttacagttat atccaatacc tttatttaaa ggatttaagt
     2101 taggttcaag attacctgta atgatgggaa tgagttatgt atttttagga gcttgtcttt
     2161 cagtagcagc taaagatggt ttagcagctc tatttggagc acagattgct gctggggtaa
     2221 tcgtattctt tgtaggattt ggagttaaga aaattagaca tatattcact ccaatagttt
     2281 ctggaactat aatagcatgt atgggacttg gactattcgc aacagctata aagaatttag
     2341 ctggaggaga aggcacacaa acatttggaa gcccaataaa cttcacagta ggagttatag
     2401 ttgcttttgt aataataatg ataaataaat acggtaaagg tttagtaaaa aattcttcaa
     2461 tattaatagg aatattagta ggttatgcta tatctttagt tttaggattg gttgatttct
     2521 cagccgttca aggagcagct atagtatctt taccaacacc agcagctttt ggattagaat
     2581 ttagaccaga gttaatagta atgtttacta ttatttacat aataggtata gctgatatga
     2641 tgggtgcctg tacaatagct acagtaggag caatggatag agaggtaact gacgaagaat
     2701 tagcatcagt tgttttagga aattctataa cttctataat ttcatcacta tttgcagctc
     2761 ttccaactgg agtatttagc caaaatacag taattgtatc tatgaacaaa gttacaagta
     2821 gatttgtaat agcactaggg gcacttgtat tattactagc agggatatct ccagcattgg
     2881 gtgcaataat gacaactata ccatcttgtg ttgttggtgg agcaacttta gtagttttct
     2941 catcaatagc aatgtctggt ttctctatta tgagtatgga tggattcact gaagaaaaca
     3001 atcttatagc aggtgtatct atagcaacaa gtatgggtct tacaactgct ccacaagttt
     3061 tagaccaatt cccagaaaca attggaactg tccttggagg gtcaagtata gtttctggag
     3121 caataatagc tatattactt caaacattat ttaaattaaa gtcacgtaaa agtgctgaaa
     3181 acgttacttc aaatcttgag gaaaatattg gataaatgta ttagatataa tatgagaaaa
     3241 ccatatggta aaatgttgta atgaaagtat tcaaaggggg atttaagatg attgatatac
     3301 taataaaaaa tgcaataatt gttacagtta ataaagacag agatgttata tttgatggag
     3361 caatagctat tcaaggtgac agaatcttgg acataggaaa tacagttgat attgagccta
     3421 agtatcttga tgctaaaaaa gttatagatg ctaatggaaa agtaatattc cctggcttta
     3481 taaatactca taatcacctg ttccaagtgt tattaaaagg tttaggtgat gatatggcac
     3541 ttcatgagtg gttaaataca atgatgtttc catcagcaaa attcttaaca gaacaagata
     3601 cttatgatgc tgcaatgctt ggatgtatgg aaggtttaaa aagtggtata actacaatgg
     3661 ttgattatat gcatactcac aatagaccag gacttacaga tggaatagta aaggcatata
     3721 aagatttagg cataagaggg gttgtaggta gaggttgtat agatttaggt attcacaaag
     3781 agcttataga agatgtggaa acggttgaaa aagatttgag aagggtattc gaaaaatatc
     3841 ataattcaga aaatggaaga ataaaaatct gtgtagctcc ttcttcaatg tgggctatat
     3901 ctgaagaaat gggtaagatg ctttggaata tagttaaaga atatgattca tattttacag
     3961 ttcatatatc tgaaacagaa tttgcaagaa cagcaacaaa ggatatacat ggagaaatag
     4021 atataaaatt acttgaaaaa tggggtatag taggtccaga agttgtagca gtacattgtg
     4081 tatgtataac tgatgaagac atggaaatgc ttaaaaagta tgacataaaa gtttctcata
     4141 atgtagcaag taatatgtat cttgcttctg gtgttgcacc tgtgccagaa atgttaaaaa
     4201 aaggtataaa tgtgagttta ggtcttgacg gtgcagcaag taataacgca caagatatgg
     4261 tagagcttat gaaactaaca gctttacaac acaaagtaaa taattgtgac cctctggcaa
     4321 tttctgcaga gaaagttctt gaaatggcta caattgaggg agcaagaact cttagaatgg
     4381 aagatgaaat aggttctttg gagattggga aaaaagctga cctagtaata tttaactcaa
     4441 tgctttctcc aaaatcaata cctcttcaca atcctgtatc aactttggta tactcagcta
     4501 gtatgcacaa tgtagagagt gttttagttg atggaaatgt aatacttgaa aatggaaaag
     4561 taactacaat tgaaagtgaa gaacaagtgt tgcttaatgc acaacatgca gcagaagaat
     4621 tatgtaagag agctaatgta actaatagaa tggaaggaca taagtggaat agcttatact
     4681 aatattaaaa taagattgta ataatattct attacaacat tagtttatct gtaggaggag
     4741 aaaatggaaa aaataaaatt aaatattaat gattacatgt atgaaataga agttgaaaag
     4801 aatgaaactc ttttgcatgt acttcgtgaa aaattaaatc taactggagc gaaacaaggt
     4861 tgtaatagtg gcagttgtgg agcatgtaaa gttttgatag atggagttga catgaaatct
     4921 tgtaaacttc ttgcaaaaaa ctgcgaaggt aaagttatat acactataga aagttttgct
     4981 aatggagaaa atcttcatcc aatacaagaa gcttttatag aagttggagc tgtacaatgt
     5041 ggatattgta ctcctggtat gattataaca acacaagctc ttttaaatag aaatgcatct
     5101 cctaatgaag atgaaattag agaagctttt aaagaaaatc tctgtagatg cacaggatat
     5161 gtaaagatta tagaagctgt aaaattatct gcagctagat tagggggtag ataattatgg
     5221 aaaaggtaat aggaaaatca taccctctaa aagatgcagc tttaaaagtt actggtcaaa
     5281 tgaaatacgt ggctgatatg aaaccacaaa atgtacttta cgctaagatg cttttaagcc
     5341 ctgtagcaca tgcaaaaata aaaagtatag atacaagtga agctgagaaa gtagtaggtg
     5401 ttagagctat agctacttat ctcaatacat cacaaagaaa atacaatggt tcattaagat
     5461 tttatgagca caaaatacct gaaaatgaag ttatattttc agatacagtt agatttgttg
     5521 gtgaccgtgt tgcagcagta gctgcagaga ctccagaaat agcagagaaa gctgtaaaac
     5581 ttataaaagt tgaatatgaa gaattgccag ctgtatttac tatacaagat gcaataaaag
     5641 aagatgctat ctgcatacat ggagattcaa atatagtttc tcaaaacaac ataaatgggg
     5701 gagatgtaga aaaaggcttc aaggaatgtg actatatatt tgaagatgaa tactctactc
     5761 cagcaataca tcatagtgca atagagactc atagtgtaat tgcacactat gattataatg
     5821 ataaattaac tgtacataca ccttgccaaa atacatttgg atttagaata atactatctc
     5881 aaatttttgg gatgtcatta aataaagtaa gagttataag acctgctatt ggaggctcat
     5941 ttggtggaaa attagaactt acaattgaac cagtagcagc cgcattatca aaaatgacaa
     6001 gaagaccagt taaaatggtt cttacaagaa aggaatctat gatatcaaca agaactcgtc
     6061 atgggtcttt tgtaaaatta aaaactggtg taaataaaga tggtgaagta atagcacaag
     6121 acataaaaat atatacaaat acaggagcat atgcatcaag tgctttaaat gttataggag
     6181 cacttagtca taaagtattt aaagtttata aaataccaaa tataaagttt actgggatgc
     6241 ctgtatatac aaatacacca atagcaggag ctatgagagg ctatgggtca cctcaaatat
     6301 ttatggctca acaagctcaa tttgcgaaaa tagcaaagga aataggtatg gatttagtcg
     6361 attttcaaaa taaaaatgca gtagagccag atgatgtcga tataatcttc cacggttctc
     6421 ttggaaatcc tagagtattg gattgtatag agcaaggtaa gaagatgttt aagtgggatg
     6481 aaaagaaaaa acttccaaaa gaagaaggaa aatatttaag aggtataggt atggcaatag
     6541 gtgcacatgg taatggagtt tttggtgcac atagagatgt tgttacattg actcttaaat
     6601 taaatgaaga tggtacgttg acactactaa caggagctca tgatatgggt aatggtgttg
     6661 taactatgca aacaatgatg gtagctgaag ttttaggaat aacacctgat aaagttgata
     6721 catttgaaac tgatacggat gcatgtacat tcaaccttgg tgactatgca agtagagggg
     6781 tatttgtaga aggtggagga gctaaaaaga cagcagagaa attgaaaaat cttatattag
     6841 aagaagcaga aaaattactt gaaacatcaa aagaagattt atatctagac aatggatgtg
     6901 taattagtaa acttgatgaa aatgtaaaag catcactttc tgatgtcgca gtatatagtc
     6961 aaagtaaatc attaagagag ttaactgttg ttgaagatta ttcttcacca gctggacgta
     7021 cttcttatgg tgtacatttt gctgaagttt tagtagataa agaaactaag gatataaaag
     7081 tagttgattt tgtagctgta catgatgttg gtagagttat aaatcctcta aatttagaag
     7141 gacaattaga aggtgggatt catatgggtc taggatacgc attgagtgaa gaattggcat
     7201 ttgatgaaca aggtagacct aaagctactg attttaaaac atataaatta tttagaactg
     7261 tagatatgcc aaaatgtcaa gttgcatttg tagatggtta tgaaaaagct gggccttttg
     7321 gtggtaagag tattggagaa tgtgccgttg taccagttgc gccagctgtt gcaaatgcag
     7381 tatataatgc aactgatgta gagatacatt cattaccaat aaaattaaaa tagtagaaat
     7441 taaagcagaa ataacaattt attgtatttg taaatagata ataaaaatag atttatttgg
     7501 tgaggagata ttattatggc aaagatatta ggtatttgtg gaagtccacg taaaggagca
     7561 acagaatatg cagtgttaga agctttgaaa gaagcagaaa ctatacctgg tatagaaact
     7621 gagtattggt cagttagagg gaaaaaaata agtccttgtg tacattgtga tgcatgtata
     7681 agaaaagaaa ctatgtgtat tataaaagat gatatccaag aattagagca aaaaatattg
     7741 gaggcagatg gaattatagt aggttctcca gtttatgata tgaatataac tgctcaactt
     7801 acagcagtat ttaatagact tcgtccaatg tatttagttc atccaggaaa acttcaaaat
     7861 aaggttggtg cagctataac tactggtgga actagatatg gtggccaaga attgacaaaa
     7921 cttcctataa taaatttctt cctaatgcat gaaatgttag tgtctggagg tttaggtgga
     7981 tgctatatag gtggtacaat atggagtaaa gatggaaaag caaaaggtgc ccaagaggat
     8041 gagacaggta tggacacagt aaaaagactt ggaaaaggtg cagcagaggc agttatggtt
     8101 tctaagtttg gtcttgaaaa atggaatgtc gtaaaagaag aattagatgt taaaaaagat
     8161 gaaaaatcac ctcttagaga ccactaaaga tttattatat tattgaatat atacaaatag
     8221 tgatgtaata gattattgca tcactatttt atgttttaat ttagatttta taaattttat
     8281 attaaaaaat atagaaacaa agtgttttga gatttatttt taaattttaa aaatgagaat
     8341 taaaaagtga gaagatagaa aaggtttttt agttattaaa ttctacatac attgtatgaa
     8401 ctaaagatag aaaagaaaaa ataataaaag cattgcaatt tctatactaa agagtcatgg
     8461 aaaaatatct agtatatatt tagtattggc atgttaattg cttatatatt aaagtataaa
     8521 aatttaacaa taatttggag gtattttaga tgttaaaaga aattaaatgg aaagtaaata
     8581 atttgccaaa gggcgataag gaaaattgta tcaaattttt aaatgaagaa gaaataacta
     8641 aggttagaaa ttttcacaaa agctttcctc aatataaaga aactccatta gcaaacctag
     8701 aaggtttagc aaaaaaatta ggtgttgcag gagtatatgt aaaagatgaa tcttatagat
     8761 ttggattaaa tgcatttaaa gtattaggtg gttcttattc tatgggtaga tacttagctc
     8821 aaagattaga tacagatata tctgagttag ggtatgacaa attaacttca aaagaaataa
     8881 aagaaaaatt aggagaaata actttcttta cagctacaga tggaaatcac ggtagaggag
     8941 ttgcttggac agctaataaa ttaggtcaaa aatctgttgt attaatgcca aaaggttc
//
LOCUS       DAEOTL010000127         8922 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEOTL010000127 DAEOTL010000000
VERSION     DAEOTL010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8922
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.129"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            9..935
                     /locus_tag="KRH82_003608"
     CDS             9..935
                     /locus_tag="KRH82_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBG8656858.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDEHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            1074..1220
                     /locus_tag="KRH82_003609"
     CDS             1074..1220
                     /locus_tag="KRH82_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656859.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(1325..1849)
                     /locus_tag="KRH82_003610"
     CDS             complement(1325..1849)
                     /locus_tag="KRH82_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656860.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGGKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(1902..2126)
                     /locus_tag="KRH82_003611"
     CDS             complement(1902..2126)
                     /locus_tag="KRH82_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656861.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            2323..3447
                     /locus_tag="KRH82_003612"
     CDS             2323..3447
                     /locus_tag="KRH82_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBG8656862.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFIVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(3921..4745)
                     /locus_tag="KRH82_003613"
     CDS             complement(3921..4745)
                     /locus_tag="KRH82_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656863.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(5093..6148)
                     /gene="ispG"
                     /locus_tag="KRH82_003614"
                     /gene_synonym="gcpE"
     CDS             complement(5093..6148)
                     /gene="ispG"
                     /locus_tag="KRH82_003614"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBG8656864.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(6330..7334)
                     /gene="rseP"
                     /locus_tag="KRH82_003615"
     CDS             complement(6330..7334)
                     /gene="rseP"
                     /locus_tag="KRH82_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBG8656865.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(7347..8501)
                     /locus_tag="KRH82_003616"
     CDS             complement(7347..8501)
                     /locus_tag="KRH82_003616"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBG8656866.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(8665..8868)
                     /locus_tag="KRH82_003617"
     CDS             complement(8665..8868)
                     /locus_tag="KRH82_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656867.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT         2929 a         1524 c          929 g         3540 t
ORIGIN      
        1 gacattttat gaatttcagc aatattttta tccaagttgc agttttattt ataattattt
       61 tagttggata ttttgtcaga aaattcaact tattagatga gcactgcaca tctaagcttt
      121 caactttgac aatgacagtt tttttaccat caatgataat tagctccatg caaattaact
      181 ttgatagtaa aatgatacaa aaaatactat tgttattatt tacatctttg attatgtata
      241 tagtttcaat tataattgca tttttattga aatacatttt aaaatgtaat gataaaaaag
      301 atttgggaat atatcagtat atagttgttt tttcaaatgt tgcttttatg ggttatcctg
      361 taattgaagc agttttaggt catgaagcaa tattctatac tgcaatattc aatttgcctt
      421 ttaacttatt ttctttcact ttaggaattt atcttttatc taaaggcagt acaagtagag
      481 gtttttcaat aaaatcactt ataagccctg ctacaatagc tattgttatt ggactttttt
      541 tatttgtaac aggacttagg ttaccccaat ttataaacga gccacttgag atgttgggaa
      601 gtataactac accaatatcc atgattatca ttggaagctt acttgctaat tcttcagctc
      661 tcgattgttt tgtcaacaaa aaattatata tagtcacttt tataagatta ttggtacttc
      721 ctgtgattgt gtattttatt ctaaaaggat ggataaatga taagatgatt ttagctatac
      781 cagtagtaat ttcttcaatg cctgctgctg caaatactgc tataatggct aatcaatatg
      841 actccaatat aacactagct tcacaatgtg tgttttttac aacactattt tcagttatat
      901 ctataccttt tataagtatt ttactcttat cttgatttat ttttttatgt attatataat
      961 aacatattca ataaattaca aatataaaca ttttattgta gtatattgat ggaatttttt
     1021 cctagatatt tgtcaataat atctatatgt attatagaat aggaggctta aatatggata
     1081 tggatttact ctttaaaata gtatttgcta tagttgctat aggtgtttct gtaaaaatca
     1141 ttaaaactgt tgctagttta gcttttaaaa tagcgttgat attgctaata attttatttg
     1201 tatatagaat gtttttgtaa acatttaaaa ataagttttt taacacaata gagaagtaaa
     1261 atagattatc tttaatgtaa attttttatt aaagacactc tattttactt ctctattagc
     1321 ttctttaaat taaattttta ttatatcttc ccataatata aacatcttca aattttccat
     1381 ctctgattac agcatatttt ttagttccct ctatttcaaa acctagcttt ttatataaat
     1441 ttaatccctt ttcattatcc acaattactt ctaatcctac tctagttaac ataatccaat
     1501 tatctgctat atctaaaagt tgttccataa gcttcttacc tactcctctt ccctgataat
     1561 tctctgcaac acttattcct atttctgcgc tatgtctcaa tcgtggagaa gaatttacat
     1621 gtaacccagc aaaacctatt acatcttttc ctccattatt attagtttca gctacaaaca
     1681 tataatcatt ttctcccaaa gaagctaaca tagcttcagt tttatcgact ctgtcactca
     1741 ttaatgccaa agtatttctc ataacactgt atgttcttct aatttcatta aaagcttgtg
     1801 catcttctct tcttataggt cttattgtta tatctatagg cttactcata ttagattccc
     1861 cctcaaacat aatctttatt tttaattaaa attttacatc tttattttat actgttcaaa
     1921 tctatgtatg cttctacctg aggtacatat atcatattat cttttatatg tgtacttcca
     1981 aattctttta attctgtacc ttctttatcc ttagttattt tatatctaat ggattccata
     2041 ccttcaacta cttcagcatg aaaaaacata ccttcatatt gtttaaatct aaaattaaaa
     2101 ttgtctttag taagttttat tatcatattt ttatctactc cttatataat tgatattttt
     2161 cttattatta gttgtatata tactgcttat tcatattaat atattataac ttatcattta
     2221 tttagtataa agttataaat agatatattt atacttattt tacaatcttt cttcaattga
     2281 tatataatat gtttatataa actaatgtat gtgaggtgaa atatgagcaa aaaaacaaaa
     2341 tatttttctt taattctctt tcctattgct ttgcttttaa attttatagc cagtaaagtt
     2401 ccaaatattg ttgaaaaata ttactcccaa ttcatagata aaataattgt acaaatattg
     2461 agtaaagttt ctggaatttt cccattttct ctctatgaga ttacaatgta cataatagtt
     2521 atatctatct tcttattttt atgttgtact ttatctacaa tttttaataa gaaaaaaaaa
     2581 ttaaacatat atttaaaaaa ttccatttta aatatattat ccattgtatc aatagtctac
     2641 tttcttttta tagtgctttg gggaataaac tataatagga ttccactaga aaccacactt
     2701 ataaataact ataatttaaa aaacaatacc tctatccaat caaaacaata tagtgttaaa
     2761 gagcttacta aattatataa attccttgta attaaagcaa atgaaactag aaaactcaca
     2821 ttacaagata aaaatggtat tgtaaaatct aatacagatt ataatggtgt cataaataga
     2881 gctcaactag gatacgataa tatcttggat atattaccta gtgttagtgg tagttattct
     2941 aagcctaagt atattatttc atcaaatcta atgtgctata caggaataac tggtatatac
     3001 tttcctttta caggtgaggc aaatgtaaat atagcaatac ctgacttata tattccttgt
     3061 acagttgaac atgaaatggc acatcaaagg ggatttgcta gtgaagatga ggctaatttt
     3121 atagcgtatc ttacttctat aaaacacccc aatattgatt ttaactattc tggatatatt
     3181 ttagctttaa attatactgc ttctgcttta agtaaggttg attataatgc atatgttgat
     3241 atttctgctg gcatttcaga ttctgtccgt agagatttaa aaaatgaaag tgaattttgg
     3301 caaaaatatg aaggtaaaat taatgaaatt tctaatgagt ttaacaattc ttacttaaaa
     3361 gctaatggcg ttactgaagg tactcagagt tatggtaaaa tggttgattt attgctaact
     3421 tattatgaat tatatccata taactaaaca ctacaattca aaattttatt catatacagc
     3481 tgatattaaa tcagctgttt tctatttaaa taaattattt aacttcaagc aatcttatat
     3541 aatttgatag tacttatact atctgtataa catttcaatt ctaactattt tagttaaaac
     3601 atttctatta tcttttttaa taaatgtttt aactaaaatt tttaaaacat aaaacttcca
     3661 cattatttca ctatctatat aaaaatctaa aaattcacat ataaaattac ataactaaaa
     3721 aatcataaat ttatagaaaa catatattca aaataaaaaa gcatgtatca aaacttgaca
     3781 catgcttata atcttatgta tatatatcat tttgtcacaa taaaaattta cttgtaacac
     3841 tgatattttt aaacaaaata gtccttattt aattaaatta acattaatta aattcgtact
     3901 cattttgcta tcattaaaca ttacttatag taattttcta atacactatt tgaaacttcc
     3961 ttcccttgaa aacttttcaa ccaattctca tatgctgagt ttttccatac actaccatca
     4021 ttaaatgtta cttgttttac acaagatata atgtacttta caccatgctc tccagttgat
     4081 tgtttccatt tatcaaacaa tagaaaggca tcattttgat tcttacctgg tgctattgca
     4141 ttttgctttg catattcttt ctccatttgt ttccattctt tcaaccaatt ttctacccat
     4201 gccttgcctt gttgtttttc aaacatactt attatatcct gtggtggtga ttgttgcatt
     4261 tttctataag tatgtgaata tgattttgga gacacaggag atatgcctgt aacaatacca
     4321 tagtctacac cagctgggct aaatccaaca cttcctactt cgccatctgc tgccacattt
     4381 tgagcatccc aatatagctc aagtggtttt ccatttttat catatgctaa gcatgtaatt
     4441 tcataatcca taattgcctt ttcactgcta tttgttaagc ttataacatt gctaggccaa
     4501 tgatatggag tatcatcata ctgtattttg ctattattta taaataatgg aatattctca
     4561 ttataaacaa gacctttact actttgaata tctgatacct tctttgtgac agtacttacc
     4621 gtatttgcta agtatacatt tgttttttct gaattggtcg tactaagaga aaatgttgtt
     4681 gtcgttccag taatcagcaa agcaacaact aaaataggta agctagatat ttttttatat
     4741 ctcacagttc ttcacctctt tttctattaa cttataataa aacaatttac caaaacatta
     4801 aaatctatgt taacataatt taccaactgt tctagtaact atatcctatc atagttacta
     4861 tcaagtttca atactattga tggaaatttt cactatatta aatctttttt taattttata
     4921 aatttacaat atgatttaac tcatacatat atagtcaaat tagaatataa gtttcttaca
     4981 tttaatgaag tttataaaat aaaaaatgac tagataatta aatactgtaa ataaaaactt
     5041 attacaaaag tatttaaaaa tctagtcaat taatatatat atgaattgta tactataatt
     5101 tttcaatctc ttctagcaac tcatcaacta atttgttacc atcaatcatt ctaactattt
     5161 cacccttttt aaataaaaga ccttcacctt tacccccagc aatacctata tctgcctctc
     5221 tggcttcacc aggtccattt acagcacagc ccataattgc aacagtgata tttttttcca
     5281 tactaccaat cttttcttca acctcattta caacactaat taagtctata ttacatctac
     5341 cacatgtagg gcatgatata actttaatct tatcatttaa aagtcccaaa cttcttaaaa
     5401 tctgtttacc aacaataacc tcttcaacag ggtcgcctgt taaagatatt ctaacagtat
     5461 ctccaattcc tttaagaaga agtgctccta cccctataga agactttatt gttcctttgt
     5521 gaacacttcc agattctgta attccaatat gaagaggata atcaactttt tttgatatta
     5581 attcatatgc atcaacagtt ttataaatat cggatgattt tagagatata actatattat
     5641 gaaaatctaa gtcttcaaga atcttaatat gtcccattgc actttcaact aatgcttcag
     5701 cagttgcaga gccatacttt tttaaaagtt ctttctctaa agaacctcca ttaactccaa
     5761 ttctaatttt taaatttctt tccttgcatt tctcaactac catcttaact ctctctatac
     5821 ttccaatatt accaggattt attcttattc catccacacc ttgttctata gcttcaaggg
     5881 ctagcttata atcgaaatgt atatctgcaa taattggtat atttacacta gactttatct
     5941 ttgctatatt tttagcagct ttaatatcag gaacagcaac tctaactata tcacaaccag
     6001 cttcctctaa tctctttatt tgagctattg tagcatctgc atctcttgta tcagtatttg
     6061 tcatagattg tatacttata ggattttctc ctcctatttt tacagttcct acacttactt
     6121 ctctcgtctt tcttctctcg taactcatat tccacctcta tatattattt tatattgaat
     6181 ctctttaaat attaaaatat tataacctac atgtatatta taaattaaaa agctatctag
     6241 ttaaataaga ataaatttca tatataaaaa ttaatttatt cttatttaaa actacatagc
     6301 ctattttctt aaaatctcta aaaactaaat cattgaaata atcttagtat atctttatat
     6361 gtgataaaaa gcataaataa cattaaagct ccaaaaccaa caacatttat catgccttct
     6421 ttatttgggt cgagtttttt accacctcta acagcttcta gtaacagcat aagtattctc
     6481 catccatcaa gtgctggtat tggtaataga tttactatac ctaaatttaa gcttatgaca
     6541 gctgctaaat acactacatt tatgatgcct gtacgagcag catctgatac cataccaata
     6601 acacctactg gtcctgctac agcattgcca atccctcctg gtacacgtcc tgtaatcatt
     6661 tgacctagaa atgttagcat ctgttttgtc atatctacag tagttttaca tgcatttact
     6721 attgacccca aaaagtcttt ttctctttgt ggttgaatcc ctatttcata ctttccattg
     6781 ttatttttag gtgttacatt tacaacttta tcacttccat ctctagttat actaagtttt
     6841 aattctccac cagaagaagt atttattata tttgcaactt catcccaagt cttaacagaa
     6901 ttaccattaa ttttatttat cttatctcct acttgaagcc ctacagcctg tgcaggagta
     6961 tctggcatta tctttcctaa tttagtcgtt ggagaaccta tatacaaaaa tactggaact
     7021 aaaagtattg ctgctaatat tatattgaat attggtcctg ctacaatagt actaaatctt
     7081 tgtaatatag acttgtttcc aaaagaattt ggacttattt gttcttcatc ttcaccttcc
     7141 atgctgacat atccaccaat tggaagtgct cttatagaat actctgtatc tttttttaca
     7201 ctatatatct taggccccat acctatagaa aactcattta ctttgatacc acttcttttt
     7261 gcaaatataa aatgtcctaa ctcatgtatt aatacaatta tactaaatag tattaatgcg
     7321 gctattatag tcataaattc accttcctat ttttttatca gatttgcaac ataagctcta
     7381 ctccatctat ctgtttctaa gatttcttct aatgttggtt cacttatgct actatgaact
     7441 tctaaagtct tctctatgta atatggtatg tcatagaaac caattttatc ctctaaaaat
     7501 tcacttacta aaacttcatt tgctgaattt aaaacagaag aataagttcc tcccattttt
     7561 aaacactcat atgccaattt taaacatgga aaagtttcta aatctggttc ttcaaaagtt
     7621 aaagtactaa attttgaaaa attcattctt tcaaagctac tttccattct atctggatat
     7681 gtaagagcat actgtattgg tagtctcata tctggacatc ctaattgagc aattattgag
     7741 ctatctgtat actgcaccat tgaatgaatt atgctttgtg ggtgaactac tacatctata
     7801 ttttcttgtt ctactccaaa taaccatcta gcttctatca cttcaagtcc tttattcata
     7861 agcgttgaag aatcaatact tatttttctt cccatactcc aatttggatg cttcaaagct
     7921 tcatttttag ttatatttgc aagttctccc tttttctttc ctctaaatgg accaccagat
     7981 gctgtaagta ttatcttttc tatatttttt ttattttctc catttagaca ttgaaatata
     8041 gcactatgtt cactatcaac aggaagaata tttacattgt atttttctgc ttctttcatt
     8101 acaagttcac cagcagttac caacgtttct ttattcgcta atgctatgtc tattcccttc
     8161 tttatagcac aaagagttgg gactaatcct atcataccta ctacagcagt taaaaggaca
     8221 tccacttcat caagtgatga tattattttt aatccttcca ttcctgctaa aacttctatt
     8281 tctatatttt taggcaacat ttcttttaat ttcaatgctt tattttcctc aaaaactgtt
     8341 acatatttag gtttaaactc tactatctgt tctagcaata attcaatatt actgttagct
     8401 gatattgcaa ctatctcaaa cttatctcta ttatctctaa ctacatccaa agtttgttta
     8461 cctatagagc ctgtagaacc taaaattgat atctttttca tataataatc ctttctaata
     8521 ataaatatac cctgtcaaaa cattataaca ctactaaaac aattattttt actattcata
     8581 gaaatttcat atattattcc acagattaaa attaatctat tattttttgt attttgtgga
     8641 atattataaa atattctagt attattaaat gccctttttt atttccacaa catcttctat
     8701 tttacagtct agtgctaaac atatcttctc cattgtatcc atagaaacag atttatcatt
     8761 tcctagtctg cctaaaacag aaatacttat acctgatata tttacaaatt ccattttctt
     8821 tatttttttg tcaattaaca atttccataa tggagcgtat gaaatcatgt tatcacctcg
     8881 caaaatatat tctatcacat tttatctatt ttggaaaatt tt
//
LOCUS       DAEOTL010000128         8880 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEOTL010000128 DAEOTL010000000
VERSION     DAEOTL010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8880
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.130"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            91..261
                     /locus_tag="KRH82_003618"
     CDS             91..261
                     /locus_tag="KRH82_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8656868.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            complement(437..976)
                     /locus_tag="KRH82_003619"
     CDS             complement(437..976)
                     /locus_tag="KRH82_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBG8656869.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAKKYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FEMDREGYKRYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFDKYERFYEEY"
     gene            complement(1115..1747)
                     /locus_tag="KRH82_003620"
     CDS             complement(1115..1747)
                     /locus_tag="KRH82_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBG8656870.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            1883..3796
                     /locus_tag="KRH82_003621"
     CDS             1883..3796
                     /locus_tag="KRH82_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBG8656871.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            3812..5188
                     /locus_tag="KRH82_003622"
     CDS             3812..5188
                     /locus_tag="KRH82_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8656872.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(5328..5978)
                     /locus_tag="KRH82_003623"
     CDS             complement(5328..5978)
                     /locus_tag="KRH82_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBG8656873.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            6449..8461
                     /locus_tag="KRH82_003624"
     CDS             6449..8461
                     /locus_tag="KRH82_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656874.1"
                     /translation="MKKSVALVNDSRKDLIDFLENNLKLVFGDSININRYFINEINDN
                     DIINDDVILVMSVERLDKIINNILDKKKVIVVRRTFREDKIYNLLSLPQGTNVLIVND
                     SDETTLETISLFYKIGVTNIRPIPYMNDNNYKNIKIAITPGVPEKVPSFISDIFDLGH
                     RYIDISTFIEIINLLQIDSKEIQSNLVKYSEEIISLDTGIKDKYKELFLKIEELDTIL
                     NLSKDGILFTSKDGEINTYNSKVKDILDINEDIYGKYIEDIFVDSLKVLLSEKEILDK
                     VVVFNKKYINVNKKNIYNRDEKMGTYYSLQEITYIKKLEQNLTKKLREKGQIAKYTFK
                     DIKTNSPKMFECIDLAKKVSKSDLSILIRGESGTGKELIAQSIHNNSNRKNQPFIAVN
                     CAAVPENLLESQLFGYDKGTFTGGLKDGKQGLFELANNGTIFLDEIGDMPLELQTKLL
                     RVLQEKQIMPVGSHNVINIDVRIISATNKNLEQMIDNSQFREDLYYRLNTIPINIPPL
                     RERKEDILIIMEDLINKKLIITPEAKKLIQNYMWKGNIRELQNVTSYLNIMCEDIVLE
                     KDLPPNLRSSDNKNTSLKLKYSKNDILNILEILILNKESDVGIGRGLILKALLDKNLQ
                     ITEGKIKKIFEYLKKEELIICSSGRYGSKITQKGEDFYNKLKYKGL"
BASE COUNT         3371 a         1120 c         1221 g         3168 t
ORIGIN      
        1 tttgttgtag aattaattta attgttatat tcaataatat ttgttataat gttattgaat
       61 tacaatacat ataaaaggga ggatttcaaa atggcatata aaattactga cgcttgtata
      121 agctgtggtg cttgtgaggc tgaatgccct gttagctgta tatcagctgg agacgacgca
      181 tatgttatag atgctggttc ttgtatagac tgtggttctt gtgcaggagc ttgtcctgta
      241 gatgcacctc aaccagaata ataattcgtt attcataaag agactgattt tattttataa
      301 atactaatca gcctcttttt aattatgtat gattcaatta atattattta tatactttat
      361 tatgttgcta cctaattcat cttaaaatac tgttagcaca tatctaatac ttttaacttt
      421 aatctaattt ataattttaa tactcttcat aaaatctttc atatttatca aaacaatcaa
      481 gacatacttt ctttccttct tcaatcctta tatattgctc agatgcaaat tcaccacaca
      541 cttcacattt aagggattta aatattcttg ctttttcagg aagtcttaac ttagtatctg
      601 taatctcaaa tatttcttca aaatcacttt ctaataaata tcttttgtat ccttctctat
      661 ccatctcaaa tggttttgac tttacatata tccttataga ttttccattt tctctattaa
      721 agaaatgata tactgatttt ccagtcatcc taagtagtaa atttccctta cccattgtgc
      781 aacttagcac tacttgtata ccatctattc cacaagcatc attttcagaa atacatacaa
      841 tttcctcatc tcctgactgt ttacatccta aatatttttt tgctgcaagt gctgctttaa
      901 atcctatagc taaccctgga cattcatgac catgaaattc aattgccttt ttccataatt
      961 cctccacaaa aaccactctc cttaatattg tttatttcca tacattattt aaatttttat
     1021 cctaatattt caaaaagcca gaggatttaa tattaaatct tctgactttc tcaatactct
     1081 ttacaactgc tcattattaa tatgtttaag ttgtctactt tccttctttc attaaatacg
     1141 ataaggtaaa taaactttct gttaagttta cattctcaac tataacacct ttcggaactt
     1201 ctaaatctaa aggtgcaaaa ttccatacac ctttgattcc agcttttaca actctattaa
     1261 taacttcttg tgctccattt ttaggtatac ataatacagc aatatctata ttattgtttt
     1321 ttataaagtc ttctaaagta tctgaatcta atacttcaaa ctctcttatc tttaaaccta
     1381 tcattctagg atttgcatca aataaagctt ttatctcgaa tccagctttt ctaaatcctg
     1441 cataattggc tatagcttgt cctaagttac ctgctcctac aagaactgcg ttgtatggtc
     1501 gatccaaccc aagaatttta cctatctcag tatgaagagc ttctacatta taaccatatc
     1561 cttgttgtcc aaatccacca aagttgttta aatcttgtct tatttgagaa gcggtaaacc
     1621 ctattatatc actcaattct ttagaagata ttctttgtat atccctatct aataagtctc
     1681 caagatatct atgatatttt gggagccttc ttataactgc cattgatata tttttatttc
     1741 ccaacatctt cacctcctaa aagtgtcctc ttttttgttt gattcacaat aaaatatttc
     1801 tttttcaaaa ctaatacata taaccttgat tatattatat caaaacatta taattttaga
     1861 tagttcaagg aggtagaaat ttatgattgt tttgtcatgt aataacttaa ataaaagttt
     1921 tggtatagat tctatattag aaaatattag ttttacagta aatgaaggcg ataaaattgg
     1981 tataatcggt gttaatggta ctggaaaaac tactttattt aaaataattt caggaattta
     2041 tggatatgat agtggagata tttacacttc taaagattgt gaaatcggat atttagaaca
     2101 aaataccaat ttttattcgg ataatactat tttggaagaa gtactagaag tttttaaaaa
     2161 tttgatagaa atggaatcct atttaagaga attagaggtt aaaatatctg aagaaagtac
     2221 aaaaacaaac tctccaatta tagaaaaaat catggatgaa tattcacata aactagaatt
     2281 attttcagat ttaaatggat atggatataa atctgaagcc aaaggagttc taaagggatt
     2341 aggatttagt gacaatgata tggataagcc aataagcata ctttctggtg gtgaaaaaac
     2401 tagagttctt ttaggaaaat tacttcttaa gaaaccaact ctattgttac ttgatgaacc
     2461 tactaaccac ttagactctg aagcgataga atggttagaa gtatttttaa aacaatataa
     2521 agggactgtc atgttaatat ctcatgatag atatttctta gaccaatccg taaatagaat
     2581 ttttgaagtt cacaacaaaa aacttaaagt atataatggt aactactcta aatttgttga
     2641 gttatctaaa atagaaaaag aactagagct taagaaattt gaagaccaac aaaaagaaat
     2701 aaaaaagcaa gaagaatcaa ttgaaagact aaaagcttat ggtagagaaa aacacctaaa
     2761 gcgtgcaaga agtaaagaaa aagcattaga caaggtagac gttttagata aaccagaagc
     2821 ttataggaaa aaagctcgta tacaatttac gccttctgtc cagagtggta atgatgttct
     2881 tcaaattaga gatgtatcta tgggttatgg agaaagaata ctttttaaag acttggattt
     2941 agatatatat agaggggaaa aagttgcact tataggtgca aatggtgttg gcaaatctac
     3001 attatttaaa ataataacta atgaactaca acctcttagt ggcaatatta aatttggaac
     3061 taatgtacat gtttcctact tccatcagga acaaaaaact cttaatttag ataacacaat
     3121 aattgatgag atttgggaaa ataatactca tcttactcaa actactttga gaaatatgtt
     3181 aggggcattt ttatttgtag atgaagaagt ttttaagaag atttctacat tgagtggtgg
     3241 agaaagagct agagttgcca tacttaaact tatactatca aatgcaaact tattgttatt
     3301 agatgagcct actaatcacc tagatattga ttctaaggaa gtccttgaag aggcattaac
     3361 taattatgat gggactatat ttacaatatc acatgataga tactttctaa atactgttgt
     3421 tgataaaatt ttagttttag atgaaaatgg aattactgaa tatctgggaa attatgatta
     3481 ttatatagat aaaaaaaggc aaatccaaga gatgagtatt atagaagaaa aagaagaaaa
     3541 aactagaact caaataaaag atgaaaaaag aaaagagaga gaacaaagag aaatagaaaa
     3601 gaaaaataga ataaaaagac aaaatataga aaaagaaatt gaaaagttag agattgaaat
     3661 tgaaaaatta gatatacttt tatgtcaaga agaagtatac tctaatccag ataaagctaa
     3721 agaagttagc caagaaaaaa ttaatttaga aaataacctt gcctctctat atgatgagtg
     3781 ggaagaattt atgtaaaaag gagaggatta tttgcaagaa ctattttctt taaaagacga
     3841 aaataaaaga ttttataaaa tacttctatc tttatgtata cctattatca tacagaactt
     3901 aatttctact tctgtaaatg taatagatac aattatgata agtagtttgg gggaaacatc
     3961 tgtagcttca gttggagttg caaaccaatt tttctttctt tttaatatgt ccttatctgg
     4021 tatcacagga ggtgctggag tttttatttc acagttttat ggaaagaagg atgtgagtaa
     4081 tataagaaaa gtcacaggtc ttacttgtgt attggcaatt gttttaagtt ttgtatttgt
     4141 tattcctgct ttactaacac caaagccaat tatacacata ttttcgtatg attctgaggt
     4201 ggtaaaactt tgtatagatt actttagtat tgcagtattt agttatccat taattgctgt
     4261 aagtactgta tttagtactg gttcaagagg tgttagaaat cctaagttag gtatgatttg
     4321 tagtgcattt gcacttgtaa caaatgttat tttaaattat ggatttatat ttggtaactt
     4381 cggtcttcct gcattgggtg taaaaggtgc tgctctagct actgttattg ctagaatatg
     4441 tgaattaatt ttaatgatta cttatgttta cctttataaa aaagactata tattaaagtt
     4501 tggtctaaaa aatctaaaag ctattgataa aatttttata aaatcttttt catcaaaaag
     4561 ctttcctata tttgtaaatg actctgtatg ggcaattgga actgtcctgt attctgttgc
     4621 atatgcaaga gctggtactt ctgctatagc agctagccag atagcaacca gtacaggtaa
     4681 tttcttcata atgacagctg tatgtattgc atctggtgca tctattatgc ttggaaatga
     4741 acttggagct gaccatatta aaagagccat tgaatatgct aaaaagtttt ctatacttgt
     4801 attttcagct ggtttaatac ttggaattat tttaatttta aatataccat tattattaaa
     4861 aatgtttagt gtttctgata gcttagcttc tgatataact aagatattct ttataatggg
     4921 aatactaatg gctcttaaat cttttaatac attggttata attggtattt taagaagtgg
     4981 aggagatact aaatatgctc tatttttaga attaggatgt atgtggttag cttctattcc
     5041 tctaactttt atagctgcat ttaaaggtgc acctatattt gtactcgttt tgctcactta
     5101 tagtgaagaa gtggttaagt ttatatttgg tgttcctaga gcattatcta aaaaatgggc
     5161 tattaatata gtaaaggaaa ttgattaata attatactat acattataag tatacaatat
     5221 ttctaaacag tctcattgaa aataactaaa gtatttttga ttttcagtga gactatttct
     5281 attttttaca gaaattatta tactttattt tgattaagta acaattttta ctcatcttcc
     5341 aaaaattctt ttacttcaaa tgccaattta tgtaattcat catagtttaa aatttcatat
     5401 gtattaccca ttttttttac tatctccttt tcagttaact ttagcagaga atggtatcta
     5461 ctttttctac taattgaata gatttcactg aaattacgaa tagcttttat attgcagaca
     5521 ttattttctt gtttatttga tatacaatag gcaataactt ctgtgcaaga aaatagttct
     5581 cttaccattc tggttttata taattcatat attcttcttg tacattttct atgaaatagt
     5641 gcaataaaat ctggtttgag ataaaactct tcaaatacat ttttttcaaa tcgaaataat
     5701 tttatattag tctttgcaaa tatatcacat ttcaaattat gttcatatat gtaactgatt
     5761 ttgcctataa attcattttc aggtacaatg tcaacaagaa atttatttcc tcctctagta
     5821 gtacactcca ctaatgcaac tccctctatt ataaagaaca cttcttgtaa gtctttatct
     5881 gatgctacaa atctttgacc ctttttatat tcaacaattg atattttgtt taaattattt
     5941 ttaataattg gatatatact tgttttttct gctttcatca aagttacctc ctttacaata
     6001 tattgtataa aatattttat ttatatgttt taatttatat tatttttaat aaaagataca
     6061 attacaacta aattaaactt gacaaattca ttctactcac gcagaataaa cttatacata
     6121 tatattttca tatataattt attttaatat aattctatat ttacaaaatt atattatcaa
     6181 tagaatttat taaaataaat ttttttgggt gtatattata atttaatcga atagaaatga
     6241 aaaatataca tacagtttaa gttttaagca acaattaggg ggatttggtg acaagatttt
     6301 taattataag aaagaaagtg tcttaatgca acttttataa agtcattata gacactttct
     6361 tttttatttg ataaatttaa attatcaaaa ttatattgct ttatacaact attttgttgg
     6421 aaactattta ttatataagg agaaataaat gaaaaaatca gtagctctgg taaatgatag
     6481 tagaaaagat ttaatagact ttttagaaaa taatttgaaa ttagtttttg gagattctat
     6541 aaatattaat agatacttca taaatgaaat aaatgataat gatattataa atgatgatgt
     6601 gatattagta atgtcagtag aaagattaga caaaattata aataatatac tagataagaa
     6661 aaaagtgatt gtggtaagaa gaacttttag ggaagataaa atttataatc tactatcttt
     6721 accacagggt acaaatgttc taatcgtaaa tgattctgat gaaactactc tagaaactat
     6781 aagtttattt tataaaattg gagtgactaa tattagacca attccatata tgaatgataa
     6841 taactataaa aatataaaaa tagctataac tccaggagtt ccagaaaaag tacctagctt
     6901 tatctcagat atatttgatt taggtcacag atatatagat atttctacat ttatagaaat
     6961 aataaattta ttacaaattg attcaaagga aatacaatct aatctagtta aatactcaga
     7021 agaaataata agtttagata ctggtataaa agataaatat aaggaattat ttttaaaaat
     7081 agaagaatta gatacaatat tgaatttatc aaaagatggt atattattta cttcaaaaga
     7141 tggtgaaata aatacatata atagtaaagt aaaagatatt ttagacataa atgaggatat
     7201 atatggaaaa tacattgagg atatatttgt agatagttta aaagttttat tgagtgagaa
     7261 agagatacta gataaagttg tcgtattcaa taagaaatat ataaatgtaa ataaaaaaaa
     7321 catatacaat agagatgaaa aaatgggcac atattatagt ttacaagaaa taacatacat
     7381 aaaaaaatta gaacaaaatc tcactaaaaa attaagagaa aaaggacaaa tagcaaaata
     7441 tacatttaag gatataaaaa caaatagtcc taaaatgttt gaatgtatag atttagctaa
     7501 gaaggtttct aaatctgatt taagcatact tatcagaggt gaaagtggaa ctggtaaaga
     7561 actcatagct cagtctatac ataacaactc aaatagaaaa aatcaaccct ttatagcagt
     7621 aaattgtgca gccgttcctg aaaatttatt agaaagccag ctattcggat atgacaaggg
     7681 aacttttact ggaggtctaa aagatggaaa acaaggatta tttgaacttg ctaataatgg
     7741 aacaatattc ttagatgaaa taggcgatat gcctttagaa ttacaaacaa aactacttag
     7801 agttcttcaa gaaaagcaga taatgcctgt tgggtctcac aatgtaatta atatagatgt
     7861 tagaatcata tctgctacaa ataagaattt agaacaaatg attgataata gccaatttag
     7921 agaggattta tattatcgat taaatacaat tccaataaat atacctcctc taagagaaag
     7981 aaaagaagac atattaatta ttatggaaga tttaattaat aagaaattaa taatcacacc
     8041 agaagcaaaa aaacttatac aaaactatat gtggaaaggt aatataagag aactccaaaa
     8101 tgttacatcc tatttaaaca ttatgtgtga agatattgta ttagagaaag atttacctcc
     8161 aaacttaagg tcttcagata acaaaaatac atcattaaaa ctaaaatata gtaagaatga
     8221 tatattgaat atattagaga tactaatttt aaataaggaa tcagatgttg gtattggtag
     8281 aggattaatt ttaaaagcac tactcgataa gaaccttcaa attacagaag gaaaaattaa
     8341 aaaaatattt gaatatctaa aaaaagaaga acttataatt tgtagttcag gaagatatgg
     8401 aagtaaaata actcaaaaag gagaagattt ttacaataaa ttaaaatata aaggtctata
     8461 aaattataat ttatcaaaca aagaaatcta ttcaggatta aagtactcct tcaataggtt
     8521 tttttatttt tcaagtaccc taaaattata atttattttg tacataaata ataggaatta
     8581 ataggaatag gataattttt ttatttccta ttttttttat ataaactagc atataaaata
     8641 tattttcttc aaaataatat tttttactga aaattgaaac tatgcaatca ttttttatac
     8701 tatacatata gataaatgat tatatttatt caatattctt ataaaaaaca aaattctcca
     8761 tcgaaaatta tggcataata attgcttatt atattaataa aacaataaaa agcaattgga
     8821 ggaataaaaa tgcaacaggc tttgaaatta aaatatcaaa ccaaagaatt aggaaaagat
//
LOCUS       DAEOTL010000129         8856 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEOTL010000129 DAEOTL010000000
VERSION     DAEOTL010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8856
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.131"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            80..1681
                     /locus_tag="KRH82_003625"
     CDS             80..1681
                     /locus_tag="KRH82_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBG8656875.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNLLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEIDEKVIQQCISASKSNGQPPTITVGSTEVYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEDSL"
     gene            1900..3489
                     /locus_tag="KRH82_003626"
     CDS             1900..3489
                     /locus_tag="KRH82_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBG8656876.1"
                     /translation="MKVNKRVLSIGLAISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYNLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDARELANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            3701..5971
                     /gene="slpA"
                     /locus_tag="KRH82_003627"
     CDS             3701..5971
                     /gene="slpA"
                     /locus_tag="KRH82_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBG8656877.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFADDTKVETGDQGYTVVQSKYK
                     KAVEQLQKGILDGSITEIKVFFEGTLASTIKVGSELNAADASKLLFTQVDNKLDNLGD
                     GDYVDFLITSPGQGDKITTSKLVALKDLTGASADAIIAGTSSADGVVTNTGAASGSTE
                     TNSAGTKLAMSAIFDTAYTDSSETAVKITIKADMNDTKFGKAGETTYSTGLTFEDGST
                     EKIVKLGDSDIIDITKALKLTVVPGSKATVKFAEKTPSASVQPVITKLRIINAKEETI
                     DIDASSSKTAQDLAKKYVFNKTDLNTLYKVLNGDEADTNGLIEEVSGKYQVVLYPEGK
                     RVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDRIE
                     TAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSKDK
                     LDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAGDD
                     RYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATPIV
                     VVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQAT
                     NAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNSDG
                     KPVDKDGKVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQVGK
                     GIATSVINKLKDLLSM"
     gene            6207..8552
                     /gene="secA"
                     /locus_tag="KRH82_003628"
     CDS             6207..8552
                     /gene="secA"
                     /locus_tag="KRH82_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBG8656878.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
BASE COUNT         3645 a          935 c         1692 g         2584 t
ORIGIN      
        1 taatatatgg aaaataaaga gaaaataaat ggaaaataat tacaatataa atataaaata
       61 taaaaatcat cagggggata tgaaaatgaa caaaaaaata ttatcattag gtctagcagt
      121 atcattaatc ttagtaaact tcaaaagtgt aaatgcatca tcagtagtag aaaaaatata
      181 cggtaaagat agatatgaaa cagcagcaaa gatagctgat aaacagactt atgaaacagt
      241 aattttagta aatacagaaa aatcacttgc agacggatta agtgcaagtg gattatcggg
      301 agctacaaaa gctccaatac tatttacaca acaaaataag ataccagcag acacaaatag
      361 atgtctaaaa aatatcaaaa aagcatatat aataggtaca gaagatacta taagtaaatc
      421 agtagaaaaa gaactagatt ctaaaaatat agaagtcaaa agaattggtg gagaagatag
      481 actaaaaaca agctatttaa tagctaaaga aatagcaact ataaaaaaag tggataaagt
      541 actattaact aatgcatata gtggagaagc agatgcaatg agtgtatcat cagtagctac
      601 tagagatgga gctccaatca tacttacaga tggaaagagt gtgccttttg atgtaaaaaa
      661 tattcaatca tattgtatag gttcagagga gataatgagt aatcttctag ttaaaaatac
      721 aaactcagta agaatagaag gaactgaccg atttgaaact aacaaaaacg taatagacta
      781 cttttttaat agtgcagatg gattctatgt atcagatgga taccaattag tagatgcaat
      841 agcagccgca ccacttacta aaaactctcc aatggtacta gtaaatgatg gaagcgataa
      901 aactgtatta gaaggagcta agaatataac ctctgtaggt gaaatagatg agaaggtaat
      961 acaacaatgt ataagtgctt caaagtcaaa tggacaaccc ccaacaatta cagttggaag
     1021 tacagaggta tataagggtg aaaagtttga cactggcaag ttaaatatag tagctaaaga
     1081 taacactggg aaggtattac caatagaagt tgatgggttt atagatacaa atagagtagg
     1141 tacatacata ttgacattaa aagctacaga cgaatgggga aaaagtacag gaaaaagagt
     1201 agaaataaaa gtgttggatg acaaatctca tgattacaac agcccagaat ttaaaaaaat
     1261 ggtatctact gaaatgtata acttaatcaa ttcctataga aaagaaaaag gcaaagagcc
     1321 tttggtagtg tctagtaggc tagaaggtat ggcaaatgca tggtctaagt atatgatgga
     1381 taaaaaagta tttgcacatt atatagatgg aaaaaatgct ccacaagtat tttctgaatt
     1441 tggaatgaga agtgaggaaa atatagcata tatttatata gattctaaga acgttcaaac
     1501 gacacaagat gcaaaagact tggcaaaggc tatatttgaa gtgtggaaga agtctccaga
     1561 atacaatgca aacatgctta gtgatgagtt ttatagtact ggatttgggc tttatatatt
     1621 atctgatggt caagtgcatg ctactcagga gtttttaaat ggaaatgaag atagcttgta
     1681 aaaaattcca taaatcttgt ttttttgtta atttactgat attataaaat gaaaatcaca
     1741 tctaaagtac tttttgtaat ctgttttgtt attgctttac aggttatggt attttaggtg
     1801 ttttttgttt tagtagttta tagattttga gggaatcact actgaggatg taatttatga
     1861 ttagctgaat tatataaaaa aattagtagg aggagtttga tgaaggtaaa taagagagta
     1921 ttatcaatag gattggcaat atcattaata atggcaggag caccaaatat caatgcactt
     1981 tcaagtatag aaaagataca agggaaagat agatatgaga cagctgccaa aattgcacag
     2041 aaacaaacat atgaaaatgt agtattagta aatacagata atacactagc tgatggatta
     2101 agtgcaagtg gattagcagg aacagttaaa gcacctatat tattatcaca aagaaacagt
     2161 ataccatcag atacagaaaa aatgttaaaa gatgtaaaga aggtttatat aataggaact
     2221 gaagattcaa taggaaaatc agttgaaaat gaattaaagc aaaaagggat agaagttaaa
     2281 agaataggtg gtaatgatag aattgaaaca agttatctta tagcaaaaga aatagcttca
     2341 ataaaaccta tagataaggt ttttataact aatggttata caggtgaagc agatgctatg
     2401 agtgcgtcat cagtagcatc aagagatgga gcacctataa ttttaactaa tggtaaaaat
     2461 gttccatttg agaaaaaaga aggtgtgcaa tgctatgctc ttggttcaga ggagataata
     2521 agtaatgatt tagttaaaaa aactaatgca gttagattag ctggagaaga tagatttgag
     2581 actaataaaa aagttataaa acatttttat agttcagcaa aagaatttta tctttctaaa
     2641 ggttatcaat tagtagatgc agttgctggt tcttctatag ctaaaaatgc acctattgta
     2701 ttggttgatg gaaatagtga taagtctgta cttagaagtg ctgataaaat cacagcacta
     2761 ggaggaatag atgaaaagac actagaacaa tgtttaagtg catcatcact ggatgcaagt
     2821 gcaccaacaa taactgttgg aaatttaaat atttatcaag gtgataagtt tgatataagt
     2881 aaacttaata tagtagcaaa ggatagcaat ggtaacgatt tgacaccaga gcttatagga
     2941 aatatcaata ctgataaggt tggtaaatac aaagttacta taaaagctac tgatattggt
     3001 ggaaagacta cctcaataag tgtagaagta aatgtacttg aatataagac taatgatatg
     3061 aatagtagtg agtttaaaag aatggtttct agtgaaatgt ataatttggt aaattcatat
     3121 agaaaagaaa aaggtaaaga gccattacaa gtttctaaaa acttagaagg gctttctaat
     3181 tcctggtcta agtacatggc agataaaggc caattttcac atgtaataga tggtaaaaaa
     3241 tctgttgaag tatttactgg atatgggttg agaagtgaag aaaatatagc ttttgtacca
     3301 cttgttacaa agagcactta tacaacaaaa gatgctagag aactagcaaa tgtaatattt
     3361 acagtttgga aaaagtcaga taaatataat gaaaatatgt taaatagtga ttttgtatat
     3421 actgggtttg gattatatat attgcctaat ggagaagtgt atgctactca agaattttta
     3481 aataagtaaa attaaatttt ttaagttatt aaatattgaa atttaagggt ataaaaactc
     3541 atatgcttgg gaaaaataat aatttcaaaa aaatgccttg caaaaagaat aaaaatggat
     3601 tattatagag atgtgagaaa tattaggaat atatggatga ttattctatg tacataataa
     3661 gagatgtaat tttaatataa tgttgggagg aatttaagga atgaataaga aaaatatagc
     3721 aatagctatg tcaggtttaa cagttttagc ttcggctgca cctgtatttg cagatgatac
     3781 aaaagttgaa actggtgatc aaggatatac agtggtacaa agcaagtata agaaagctgt
     3841 tgaacaatta caaaaaggaa tattagatgg aagtataaca gaaattaaag ttttctttga
     3901 gggaacttta gcatctacta taaaagtagg ttctgagctt aatgcagcag atgcaagtaa
     3961 attattgttt acacaagtag ataataaact agataattta ggtgatggag attatgtaga
     4021 tttcttaata acttctccag gtcaagggga taaaataact acaagtaaac ttgttgcatt
     4081 gaaagattta acaggtgctt cagcagatgc tataattgct ggaacatctt cagcagatgg
     4141 tgttgttaca aatactggag ctgctagtgg ttctactgag acaaattcag caggaacaaa
     4201 acttgcaatg tcagctattt ttgacacagc atatacagat tcatctgaaa ctgcggttaa
     4261 gattactata aaagcagata tgaatgatac taaatttggt aaagcaggtg agacaactta
     4321 ttcaactggg cttacatttg aagatgggtc tacagaaaaa attgttaaat taggggacag
     4381 tgatattata gatataacta aagctcttaa acttactgtt gttcctggaa gtaaagcaac
     4441 tgttaagttt gctgaaaaaa caccaagtgc cagtgttcaa ccagtaataa caaagcttag
     4501 aataataaat gctaaagaag aaacaataga tattgacgct agttctagta aaacagcaca
     4561 agatttagct aaaaaatatg tatttaataa aactgattta aatactcttt ataaagtatt
     4621 aaatggagat gaagcagata ctaatggatt aatagaagaa gttagtggaa aatatcaagt
     4681 agttctttat ccagaaggaa aaagagttac aactaagagt gctgcaaagg cttcaattgc
     4741 tgatgaaaat tcaccagtta aattaactct taagtcagat aagaagaaag acttaaaaga
     4801 ttatgtggat gatttaagaa catataataa tggatattca aatgctatag aagtagcagg
     4861 agaagataga atagaaactg caatagcatt aagtcaaaaa tattataact ctgatgatga
     4921 aaatgctata tttagagatt cagttgataa tgtagtattg gttggaggaa atgcaatagt
     4981 tgatggactt gtagcttctc ctttagcttc tgaaaagaaa gctcctttat tattaacttc
     5041 aaaagataaa ttagattcaa gcgtaaaagc tgaaataaag agagttatga atataaagag
     5101 tacaacaggt ataaatactt caaagaaagt ttatttagct ggtggagtta attctatatc
     5161 taaagaagta gaaaatgaat taaaagatat gggacttaaa gttacaagat tagcaggaga
     5221 tgatagatat gaaacttctc taaaaatagc tgatgaagta ggtcttgata atgataaagc
     5281 atttgtagtt ggaggaacag gattagcaga tgccatgagt atagctccag ttgcatctca
     5341 attaagaaat gctaatggta aaatggattt agctgatggt gatgctacac caatagtagt
     5401 tgtagatgga aaagctaaaa ctataaatga tgatgtaaaa gatttcttag atgattcaca
     5461 agttgatata ataggtggag aaaacagtgt atctaaagat gttgaaaatg caatagatga
     5521 tgctacaggt aaatctccag atagatatag tggagatgat agacaagcaa ctaatgcaaa
     5581 agttataaaa gaatcttctt attatcaaga taacttaaat aatgataaaa aagtagttaa
     5641 tttctttgta gctaaagatg gttctactaa agaagatcaa ttagttgatg ctttagcagc
     5701 agctccagtt gcagcaaact ttggtgtaac tcttaattct gatggtaagc cagtagataa
     5761 agatggtaaa gtattaactg gttctgataa tgataaaaat aaattagtat ctccagcacc
     5821 tatagtatta gctactgatt ctttatcttc agatcaaagt gtatctataa gtaaagttct
     5881 tgataaagat aatggagaaa acttagttca agttggtaaa ggtatagcta cttcagttat
     5941 aaacaaatta aaagatttat taagtatgta atataaatat aataatataa aaaggcttct
     6001 tatatgagaa gtctttttat attatgtttt cgaatacaaa aaaagagact aaatttagtc
     6061 tcttttttat gtgagaaata cttaaatata taaagatgta atttatttaa gtatgattat
     6121 tatactatac aataaaataa ttgtctacta ttctataatt ttaaggtata ataataattg
     6181 tatgataaaa aaggaggtca aaaaatatgt cagttttaga tgcaatctta gataaagcgg
     6241 atgaacaaga aattaaaaaa ttaaatttaa tagtagataa aatagaatct ttagaaaaag
     6301 atatggaaat caaagagaat gaacaattaa aagaaatgac aaatactttt agacttagat
     6361 tagacaaagg tgaaagtttg gatgatatac ttccagaagc atttgctgtt gttagagagg
     6421 tctcaaaaag agttttagga atgcgtcaat ataaagttca gttaattgga ggtatagtaa
     6481 ttcatcaagg aaagatagct gagatgaaga ctggtgaggg gaaaacttta gttgaggtag
     6541 ctccagtata tctaaatgct ttaacaggaa aaggtgtaca tgtaattaca gtaaatgatt
     6601 atttggcaga acgtgataaa gaacttatgc gtccagtata tgaattttta ggattgactg
     6661 taggtgtaat tttatctaac caagacccaa gtataagaaa agaacaatat aaatgtgata
     6721 taacttatgg aacaaatagt gaatttggat ttgactattt aagagataat atggtgccag
     6781 atttgtctca taaagtacaa agggaactaa actttgccat agtagatgag atagactcaa
     6841 tattaataga tgaagctaga actccactta ttattgcagg agatggtgat gaagatttaa
     6901 aactttatga gttagcaaat aactttgtaa aaactgttaa agaagaagac tttgagatgg
     6961 atagaaaaga taaaactata gcattaacag caagtggtat aagcaaagct gagtcatttt
     7021 ttggtataac aaaccttact gatataaaga atatagaatt atatcatcat ataaatcaag
     7081 ctttaagagg tcataagctt atggaaaaag atgttgacta tgttatctca aatggagaag
     7141 taatgatagt tgacgaattt acaggaagag taatggatgg tagaagatat acagatggac
     7201 ttcaccaagc tatagaagcc aaagaaggtg ttgagataaa gaatgaatct aaaactatgg
     7261 ctactgtgac ttatcaaaat ttcttcagac tatatgaaaa actttctggt atgactggta
     7321 ctgcaaagac agaagaaggg gaatttgagt caatctataa attaaatgtt gtccaaatac
     7381 caactaatag accagttatt agagctgatt tgcatgataa ggtatttaaa acagaagaag
     7441 aaaagtatag tgctgttgta gaagaaataa taaggataca taagactaga cagccaatac
     7501 tcgtgggaac agtttctgtt gaaaaatctg agaagttatc taaaatgctt aagaagcaag
     7561 gtattaagca tcaagtctta aatgctaaac aacatgataa agaggcagag gtaatttcta
     7621 aagctggtaa attagatgct ataacgattg ctacaaatat ggcaggtaga ggtacggata
     7681 tttctctagg tgcaggagat aaagaagaag aagaaaaagt taaaaattta ggtggtcttt
     7741 atgttatagg aacagaaaga cacgaatcaa gaagaattga caatcagctt agagggcgtt
     7801 ctggtcgtca aggagaccca ggtacatcaa gattctttgt aagtcttgaa gatgatgtaa
     7861 taaagcttta tggtggaaaa actatagaga aacttatgaa gagaacaagt tcaaaggaaa
     7921 atacggctat tgaaagtaaa gcacttacaa gggctataga aagagcacaa aaaggtgtag
     7981 aaggtaaaaa ttttgaaata agaaaaaatg ttcttaaata tgatgatact attaatgagc
     8041 aaagaaaggt tatatataat gaaagaaata aagtgttaaa tgatgaagat ataaaagaag
     8101 atattcaaaa aatggttaaa gacatcatac aagaagcagg agaaacttat ttaattggaa
     8161 gaaaaagaga ttattatgga tattttaaac atttatatag tacatttatg cctgcagata
     8221 cattactaat acccggtgta gataaaaaaa gtgtccaaga gataattgat agcacatatg
     8281 aaatttcaaa aagggtttat gacttgaaaa agatgatgat tggtattgat aaagttgcgg
     8341 agttagaaaa aacagtactt ttaaaagtgg ttgatcaata ctggatagat catatagatg
     8401 ctatggaaca gttaagacag tatataggtc ttaaatctta tgctcaaaaa gatccgttta
     8461 aagaatatgc tttagaagga tatgatatgt ttgaagcttt aaataaaaat ataagggaag
     8521 caacagtaca atacttatat aaatttaact aaaaaagttc atgtaatttt tattaaatga
     8581 aaaataaaat attttgattc tttatattgt aattacaatt aaataattaa ggaatacaaa
     8641 tgaaaaagaa gctgaaaatc agcttctttt tctgtgtgag aaatacggaa aaaagagatg
     8701 cttgaaattt ctttcttcca tttaatatta tactataaag aagatgaaaa gtctattagt
     8761 tataaactgg attattaaaa aaaattacaa ttttgttact tttttgtata cataaatatt
     8821 aaaaaaataa aatataagaa aaagtttata tctttt
//
LOCUS       DAEOTL010000130         8665 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEOTL010000130 DAEOTL010000000
VERSION     DAEOTL010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8665
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.132"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(151..3048)
                     /locus_tag="KRH82_003629"
     CDS             complement(151..3048)
                     /locus_tag="KRH82_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBG8656879.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTEADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(3375..3983)
                     /locus_tag="KRH82_003630"
     CDS             complement(3375..3983)
                     /locus_tag="KRH82_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBG8656880.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(4243..4788)
                     /locus_tag="KRH82_003631"
     CDS             complement(4243..4788)
                     /locus_tag="KRH82_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBG8656881.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(4906..6729)
                     /locus_tag="KRH82_003632"
     CDS             complement(4906..6729)
                     /locus_tag="KRH82_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656882.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(6742..8517)
                     /locus_tag="KRH82_003633"
     CDS             complement(6742..8517)
                     /locus_tag="KRH82_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656883.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         2896 a         1480 c          778 g         3511 t
ORIGIN      
        1 attattgtat tctcttgatt ttttttctca tttgatttat tttattaata aaatcgtaaa
       61 aattaataca aaaataaaga tgctctaaaa tagtatactc aactaatatt aaagcacctt
      121 tattatatat gtcattattt acacattgct ttattctttt ttaaaagcga ttttttcaaa
      181 ctcttttaca ggcattggct tagaaaacaa atatccttgt accatatcac acccaatttg
      241 ctttagaaat tctacttgcg aaatagtctc tacaccttct gatattactt tcattttcag
      301 ttcctttgcc attttaatga cattagatat aacaattttt tcattattac tctcatcttt
      361 ttctgtaaaa aatgctctat ctagttttaa tatgtcaaca ggcaattctt ttaaaagatt
      421 aagagaggaa tatcctgtac caaaatcgtc catagagatt acaaatccct tttctttcaa
      481 attgttcatt gtatcaagta atccttctat attatctaat actgctgttt ctgttagctc
      541 taattctata agtcttgtcg gaattttgta tttatctaca attaatttaa actcctctat
      601 aaaattacta tttacaaaat gcattcgaga caagtttaca gatataggta ctactttttg
      661 tccttcatcc atccattctc taatcttttt acacacttcc tcaaatacat agaaatcaat
      721 atttacaata aaaccattcc tctcaaatac aggaataaat tctattggtg gtattagacc
      781 tttttgtgga ttatcccaac gaacaagagc ctctgcccct ataatttgat aatctgaaag
      841 gctatattta ggttgaaaat aaacaataaa ttctccatta ttaagagcat ctaccattga
      901 attttcaatt tctttctctt ttaatatttt tttgtgcatt tccttatcgt aaaaagcaaa
      961 tgaattttta tgaccacctt ttatagtttt tcttgcagta ttagctctat ccataatagt
     1021 atttatgtca ttatcacttt tacttatttt atatatacca caatctaaaa tcaatttata
     1081 atagtttatt ttaggattac taagtatttg aaccttattg taaatattgt ttaaccttgt
     1141 tttaatatca tcatctgtct tatacttaat aagaagaaca aaatggtcag cagaaactct
     1201 tgcaaaaatt tcatcttcct ttaattcact tgcaatagta tttgatatat gtatcaaagt
     1261 atcatttccc atatcatatc caaacatatc atttatatat ttaaatttgt caacatctat
     1321 ataaaacaac gcatattctt ctggattatt cttagcaaac agtttattag aatttatttt
     1381 aaatttatct atactatctg cttctgtcaa tgggtctgta tatgctatct tccttagata
     1441 atcctctttc ttctttttat tataaattat atatttaata gcaattaaga ataaaataca
     1501 tacaaaagaa ataatttgta ttgaatattc tttaaaaatc acaccaaatg gtactttata
     1561 aggtttgtca atagtattag aatatataca atcacttaat tcttcttcag taattttgtc
     1621 tattgattta tttaaaatag acactaatat agggtcagtt ttatttgata cccctatacg
     1681 catcccatag cttgtatcta aaacagatat aacagataaa ttctcactct ttccttctct
     1741 taaaagttca tcaaactgat aagaactaag tatcattaag tttgctttac cttcatttat
     1801 agcgtttaga caactttcta cactcttata agatgttgtc ttagcatttt caaaactctt
     1861 ttctatataa gaatcaatag acttataact actagttaaa gcaatattta aatcattatt
     1921 gagattggta tccaattttc ctaccataat cattggaata tttatgtatg gatttgtcaa
     1981 tttcatatta aatcgttttg ccttatcatt ttcattgatt gagccacata gcatagttgc
     2041 cttaccactt tttatgtaat caagactctc attataattt tttgttttaa tatattcaaa
     2101 ttttatacca catttttttg atataattga cattaaatcg gaacttatac ctttaaatga
     2161 attgctttct ttatcataat actctacagg agaccactct gaatcatata ccatagtaag
     2221 ttttgggttt gctttaataa aattcatttc ttgccgagta aatgctatgg aattattgac
     2281 ctctcttttg aaatattttt tatataattc caactcataa tacatatcat ttatttttaa
     2341 ttcttttaaa gcataatcta attcttttac caaattaggt ttatcttttg cagtagcaaa
     2401 ataaaaaggt tctactgaaa atttgctaac tattttcatt cctttagcat ttataatact
     2461 tccacaaaca aatgcatctg cctttttttc attgacggac tcaattaatt catcaataga
     2521 attacagtat atatattcaa ctgaaaaatt attttcttct ctatacttct caaatgcagt
     2581 attatgaaag tttcctctaa gtacagctac tctcattccc ttaaaggaac ttatatcttc
     2641 ataaaacata ttattgttac tatcctttgt atatagtgca ctatattcat atcctgaact
     2701 tagtttagga aaattaaata gtttatttct ttcatcattc ttctgtaaag gtccgagtaa
     2761 gtctatttca cccttttcta gtctgtctaa acattcttcc caagaccctt ttacaaattc
     2821 atattcccat cttgtatatt ttgagatttc tcttagataa tcataaccat atcctgtata
     2881 agaatgctct tttgatgagg atattattcc gtagtcatca caatatccaa ctcttatttt
     2941 ttttgaattt tcagactcat cagcaaagca tagtatattg ttaaaacatg atataataag
     3001 taaaaatatc aaagaaagta tcaagaagtg ctttttaaat gctttcatat ttaaaaacct
     3061 ccaatttgcc aacttacttt aacttatttc gttttctagt tgtaactact tttattgtaa
     3121 tggtaaatat atcaaattgc aatattctca tataatattc ttattcaact ataatgaatt
     3181 tattattatc tatttaaata cactatctaa tattagtttc ttataagtca taaaagcaca
     3241 actaacacta taattctagt gattaatttt atttcaaaaa atataataac actactaata
     3301 ttttaaatat caatagtgtc ataaaaactt ttcagattaa ttaaatcttt ctatatattt
     3361 tataataatc taaatcatgc taaatattta gacagaaaac ttttttcttt aatagtaaat
     3421 acttttgttt gaatatcaga ataattattt gaatatctat ctataaaacc atgatttgca
     3481 tctaaaatct caatttggat attttgtttc ctagaaagtt ggtaagaaat agaatcaaca
     3541 tcaaatgaat cgtgctttgc aaatactaat aaggtaggac attttggaat tacatccatg
     3601 taatctctaa tccgagagcc ataacaacaa attatgccat cacaaaaaga atcttcactg
     3661 catctccatg caatagttgc tcccacgcta tacccagcaa caaatacata tttatactct
     3721 gattttaaat catttataag cttttcaact tttttataaa tatcaaaacc aacattattt
     3781 ataaaaaaat catatgcctc ttggactttt gaatatggaa aaactctttt ttctcccaga
     3841 agttcaggac aaaatacatc atatccatat ttataatact tttgacaaac atcttctata
     3901 aagctattaa tcccatagat ttcatgcaaa acaacaatag ctacatcact tttatgtata
     3961 tactttatca gattatccac cacctttaca aaacagcaaa ttttttatac ttagtttaat
     4021 atattcttct ttacatgtca atttactttt ctaaaatcaa atttattttt ggattaatca
     4081 tttattttta aaagttgtgc attattacta ttaaattatt ctctattatt aaaaatataa
     4141 tcgttagaaa taaaaaataa agtacaaata attaaaaaat atctcactca taactttaaa
     4201 aattataagt gagatactcc taaaatctac tttatattaa atttattttc caaaatatct
     4261 atttaataat cctaaaaatg ctttaccatg tctagcttca tctttacaca tttcatgtac
     4321 tgtatcatgt atagcatcta atcctaattc ttttgctttc ttagctaatt ttaattttcc
     4381 atcagttgca ccatactcag catcaactct aactcttaag ttttcttttg tatctgcaac
     4441 tacaacttct ccaagaagtt ctgcaaattt agcagcatgt tcagcttctt caagagctat
     4501 tctcttataa gcttctccta cttctggata accttctcta tcagcttgtc tactcattgc
     4561 taaatacatt cctacttctg tacactcacc aacaaagtta gctcttaatc cttcgattat
     4621 ttcttcatct acaccttgag ctactcctat tctgtgctca tcagcccaat ttttttcgcc
     4681 tttcatttct tcaaatttat cagctccaac tttacatact ggacattgtg ctggtgcagc
     4741 atctccttca tgtatatatc cacatactgt acaaacaaat ttcttcataa ttactttcct
     4801 cctaaatttt atatatcaaa ttaaattttt tatttattaa gttagtctat atatacccgc
     4861 accatatacc tttaaacaat ttttttaaaa gttttttcta aatacttatt ttccctgtgt
     4921 caataatatg tttctataat aatgtccctt taattttatc aattctttat gatttcctga
     4981 ttccacaatt ctaccatttt ctaaaactat tatattatca caatttgata tagtacttaa
     5041 tctatgagct ataattatac ttgtctttcc ataagttaaa ttatttattg cttcttgaat
     5101 tttagcttct gttgctatat ctatgttact tgtagcctca tccaaaataa gtattggagc
     5161 attttttaat actgctctag caatacttat taattgtttt tgaccttcac ttaaatcttc
     5221 acccctatcc gataatacag tactatatcc ttcacgcatt ttaactataa atttatgtgc
     5281 atttgctatt ttactagcat atataacttc ttcatcagta gcctccagat ttccatacct
     5341 tatattttcc ataactgtat cattgaatat ataaccttct tgtggaacta ctccaaaaca
     5401 agttctcaaa tagtttctgt taatagagta tatatcctta ccatctaaaa atatacttcc
     5461 ttcatctata tgataaaaat ttgtaattag atttataata gttgtttttc cacttcccgt
     5521 ctctcctatg atggcatttg atgtgccaga tttgattttt aggtttatat tatctaaaat
     5581 tttctttttt gaatcataag aaaaacttac atctttaagc tcaatttctc cctttacaaa
     5641 atgagagttt aaattaccat ctttattatc gttaatctca cttttaaaca tgttatgcac
     5701 ttcttgctct tcttgttcat ctataatttc aaaaactctt tcacatccag ctatggctga
     5761 aagtaatgta ttaaatagat ttgctaattc atttaaaggt cttgtgaatt gtcttacata
     5821 acttaaaaaa ctagctataa cccctatggt tataatatct ttagatgcaa gaatgcctcc
     5881 tataatacat atagttgcaa atcctatatt actaatcaca ttcataatag gcattaaaag
     5941 agaagtgtaa atttgcgatt taagggaaat atttagaagt ctatcattga cttctttaaa
     6001 atcatttaca gattttcttt cataattaaa agattttact acatttatgt ttgatatcat
     6061 ttcttcaata tgtgcattta gttttcccaa ctcaacttgt tgttgcttaa aaaaaactct
     6121 agttctcttt gcaataaaat tactcacaaa cattactatc ggtattaata ttacactgca
     6181 aaaggttaaa attgggctta atacaaacat cataataaaa gtcatcaata tgtttaagat
     6241 tcctgtaatt aactgtacta atgaatttga tattcctgta ctgatattat cgacatcatt
     6301 tgtcactcta ctcataatat ctccagtaga acttttatca aaaaaggtta ttggtagatt
     6361 tttaaatttt aaaaataaat tacttctcat ttctctgact atactttgag ataatctagc
     6421 tgtacatatc cccttagaca gtttaactga aaactcaatt atataaaatg aaagtaaaat
     6481 aattattcct tttaagaaaa tggattttga ataagtatcg atatctatta tgtcaactac
     6541 ctttccaata gtatatggta ttacagttga tataattgaa tcaattatta ctagcaaaaa
     6601 aataaatcta gtaatcttct tatctttttt aaagtacata aaaattcttt taaacgtttt
     6661 tttaaaatct ttaggctttt cttttttctt taatctactg accttctgat ttccagtact
     6721 taaattcaat atacttcctc cttaatttac atcttcactt actaaatttt gcaacgcaaa
     6781 aattttttta taaattggag aactaaccag taaatcttca tgtgtagcaa atccaaccac
     6841 ctcaccctca tccaagacta aaatcttatc acagtcaatt atagaactaa tcttttgtga
     6901 aatagttatt acagtacatt tcttactttc cttttctctt aaattactta tatactcttt
     6961 tatattcttt cttataattg tctctgtatt aatatccatt gcactaaaac aatcatcaag
     7021 aattaatatt tgtggttttt tggctatagc tctagctata gtaattcttt gtctctgtcc
     7081 tcctgataaa tttttacccc tttggaataa aacttcatca taagtatttt cgagttttgt
     7141 tataaattga tttgcatttg ctatttcaca tgattttaca acatcctctt tgcatatatc
     7201 tctatttccc ataactacat tctccaatat actttttcca aacacactac tattttgaaa
     7261 tactacacct attcttgccc ttaaactttc ttcagaaata ctgtatatac tacgtcctcc
     7321 aatcttaata tcacctttat caattatata taatttttga attaaattta ctaaagaagt
     7381 ctttcctgaa ccagtttgac caatcacacc aatattttga ccttcttcta ttttaaagga
     7441 tacgtttttt aatatttttt catctgtatt tttgttatac gaaaaatcta cattttcaaa
     7501 aattatatca cagtttacaa actttaaatc tttttctcca acatctaaac tttcttctct
     7561 ctcaattact tcttcattct catcaaccaa aacctcactt attctctcat aagatgcttt
     7621 tgccctaaca aaaacattaa aaacatgtga aatcattata agagatgtta atattctagt
     7681 catatagttt acataagcaa ctataatccc aattttaatt tctcctgaat aaattaaatg
     7741 ccttccaatc agtaatatta ttattatgga aacattaatg attattgtaa ttgtcggtct
     7801 aaaaaatgac atcatagttg tagcttttct actattttta aaaagttcat catttaactc
     7861 ttcaaagctt tggttctcat aatcgtatct acaaaatagt ttaactactt ttattccact
     7921 taaaaactgt cttaattttg aatttacttt atctgtactt tcttgtacat ttttaaataa
     7981 tctataccct atcttcatat taagcaatat tataataaat ataattaaaa ctgcaattag
     8041 aataattatt gacatcttta aatttaattt tatagctata attaaacttc ctatacacat
     8101 tattggtgac tttataaaaa ctctcatcat tccattaacg aattgttgca tttgattgat
     8161 atcattagta attcttgtta ttaatgaagc tctaccaaat ttatctattt gttttaatga
     8221 gtatgtattt atcttttcaa atacatcctg tcttaaatca taagaaaaat gctgagaaac
     8281 tcttgccgag attacacttc ttattattgc aaatattgca cctaaaaaag ttatacctat
     8341 cattatagct cctgttgata gtatgtagtc taagttctta tttgaaaccc ctatatctat
     8401 tatttttgcc attatagttg gttgagctaa atcacaaaaa gcttccaatg ttaaaaaaaa
     8461 tactgctgtt agaaataata ctatatattt ttttatgtat tttttaaaat acctcattca
     8521 atcatccctt catagaattt tctcattacc aaaagtatat cataatggct aatttaattg
     8581 attatatcaa ttataaatat ttgatttatt attaattttt ataccatata ttttataaat
     8641 tatttgtttt tatttcctat attta
//
LOCUS       DAEOTL010000131         8626 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEOTL010000131 DAEOTL010000000
VERSION     DAEOTL010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.133"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1732)
                     /locus_tag="KRH82_003634"
     CDS             complement(<1..1732)
                     /locus_tag="KRH82_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBG8656884.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFS"
     gene            complement(1746..2675)
                     /locus_tag="KRH82_003635"
     CDS             complement(1746..2675)
                     /locus_tag="KRH82_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8656885.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            2903..3091
                     /locus_tag="KRH82_003636"
     CDS             2903..3091
                     /locus_tag="KRH82_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656886.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            3084..3785
                     /locus_tag="KRH82_003637"
     CDS             3084..3785
                     /locus_tag="KRH82_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656887.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            3787..4710
                     /locus_tag="KRH82_003638"
     CDS             3787..4710
                     /locus_tag="KRH82_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBG8656888.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            4867..5790
                     /locus_tag="KRH82_003639"
     CDS             4867..5790
                     /locus_tag="KRH82_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656889.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            5783..6520
                     /locus_tag="KRH82_003640"
     CDS             5783..6520
                     /locus_tag="KRH82_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656890.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            6531..7304
                     /locus_tag="KRH82_003641"
     CDS             6531..7304
                     /locus_tag="KRH82_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656891.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            7320..7472
                     /locus_tag="KRH82_003642"
     CDS             7320..7472
                     /locus_tag="KRH82_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656892.1"
                     /translation="MKKIKKLIILIVFLFLFGMLHCYTEWKFNNDPPKGVIERINEWT
                     DKIGLD"
     gene            complement(7845..8453)
                     /locus_tag="KRH82_003643"
     CDS             complement(7845..8453)
                     /locus_tag="KRH82_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBG8656893.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFAISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
BASE COUNT         2852 a         1428 c         1249 g         3097 t
ORIGIN      
        1 cagaaaatct agttatatct cttgaatata taaaatcatt tccatatatt aatctttcag
       61 cttcaagttc tgattctttt cctgtaaata ctcctaatac taatatattt tgctttctag
      121 cttttctcac ttcattggct gtatctctca aaccaactat acccctataa gccttttctc
      181 ctcttaatgt tctctcacta ctttttccta tctttacatc atttggtctt ccatcgctga
      241 gaactatcag gattttattt tcttcatctc tatttattag accactacat atagatttta
      301 ttgccaaacc atctctatta ttaccagcac aaaaatattc aaatatattt tcactatttt
      361 ttatactatc atcataatct ttaaatcttt ttaatattgt atagtctaaa aaactagaaa
      421 atcccatcac tctatttggt atgccaactt ctgttagagc atttgcaatt atgtaagctt
      481 gaattgccac atttccctga tttctacttt gagagccact tgcatccaat aatatatcaa
      541 taacgtattt ccctttttca ttttctatat ctttataaaa tattttatta ttattacttc
      601 taccaactct ccaagctcta tttgctaata tagtaccaca atcagaatat actctacttt
      661 tagcattttc ttctattaaa attcttgaca gactttcttt taatctcttt atttgctgtc
      721 tatacattct agcatgttct ctaaattttc ctaaattatt ttctttttgt cttgttacat
      781 attttagttg aaatacatta ttacactcac ttctaagaac tccatctgta aagtgtattc
      841 tacaaccttc atgaacattt ctacaatttt gtgtctcaat ttttttaatt tcacctttac
      901 tcaaataagt ttttccataa taatgttcta tttttgaata tatcttattt gcagtgtctt
      961 catcaacata tataactcgg tctgctgaat tgctacattt agaatcatca aaatccccta
     1021 caccttctac aagcatggat gaagatattg aatctatatc actttcaata atattttctt
     1081 cttcatcact ataaagttct tcatacatga aatcagcaaa tgtatcaaaa tttacttcta
     1141 cactttctac attattttca tcaataagac tattttcttc tccatttaat atgtattcaa
     1201 aataagttaa atatataaca tctaatgctt ttaaaatctc cataatatct tgattggtat
     1261 ctatatttct tatatcatta actattcttc tagtcatact atctaatgct gggtgcttgt
     1321 ccatactata aagtacaaat gtgtatttaa ttttatccat aatattatca ttgtgtattt
     1381 tggtaaaacg tgaaacaata tctttataag catttcttct tatgtcttct atccctggcc
     1441 tatctttaat gaccttttct tcaactattg tatttaatat gacttgaatt agacccagta
     1501 taatatcttt gttgtatcct tttcttattc tatttgtaag atatttttta actatatccc
     1561 aatctacata ctttcttcta gcacctgcaa ttattgcgaa atatagacct atttcttttg
     1621 aagagtaatc tttttctgat atatctatac tttcattgta atcaccagct attgtccatg
     1681 ataggttatt agctctattt tcaaattcat aatcatcata tatccatttc ataatctcac
     1741 ctatattaaa tatgacttat tggaaacaca tctatactct cccatttatt aggtattcta
     1801 gttttaatta catctccaac catttctttc tcatatacat caaaagtctt tcctgtaagt
     1861 cccatattaa ttgcaagagt tggttttaat cctcttctta tagtcttaag agatgccata
     1921 agaccacgta aatcaatagc tttactagat atctctccat tttgagactt caattgtaaa
     1981 tctaaaaata ttcctgcaaa gtgtattaat ttttcttcat cagcatctga aaattcattt
     2041 tttaaaatca tcattaactt atcttcttct ataggaggaa tatctattac cataaatcta
     2101 gataccagtg cttcattaag ttcttttgtt cctgcatatt cataattcat agtcccaata
     2161 aatcttgttg ctggatgtag attgactctc tcatacccag gtacatcaat tattcttcta
     2221 tagtctaaag ctgaatgtac cacaactata gcatcatttt ttgccatatt aatttcatca
     2281 aataccccaa aacctccatt aatagcacac tcataaactg agcctcttct aagtttaact
     2341 tcattgtcta taaatgtatc tgtacctata agtgttgaac tgtctgtatt tatatgaaat
     2401 gatgtattcc actgaggtct attaaatatt tcccctagat tatcagcaag taagtttttt
     2461 cctgttgcct ttggtcccga taataatata ttttcttctt ctaaaatagc tgctatacac
     2521 atagacaaga tatctttacc ataaaaataa gttttagact ttgttactct gtattctaaa
     2581 tctttttcta atccataata atttctaaaa tacagtacat cttcaataag tttttcatct
     2641 accccttgca cccttagatt atctattata tccatatttt tacccctttt atataaatag
     2701 tatttgtttc atttcttatc accattttag cataaaagga tataagctaa aattgatttt
     2761 ttaatctccc cattttaagt aaaaccatgc accattttat cactacaaaa ttaagagtac
     2821 tacttactga tatttcttga ttttgttcgt ctatacgtat ataatatatg ctgataaatt
     2881 atgaggaaag gatgattgaa atatggaata tatgtcttgc ccagaagtag caaaaaaatg
     2941 gggtatttct gaaagaagag tacaaaaact atgtgaagaa agtcgcatac caggagtttc
     3001 aaaactcggg tatatgtggc tgataccaaa gaacgcagaa aagcctgttg atggtagaac
     3061 aaaaagaaga aaggaagtac aatatgaata gcgttttaat tatagatgat gacaaagaac
     3121 tttgtgctct tatgaaaaaa tgtgttgagc aagaaaattt atctgctatt actgcacatt
     3181 gtggtgcaga aggtctacat ttggtcgata aaaatagaca cacactctct cttgtaattt
     3241 tggacataat gatgccagat atagacggtt ttcaagttct gaaaaaaatt agagaaacaa
     3301 gtaatattcc agtaattatg cttactgcta aaaatgacga ggatgataaa gtttccggac
     3361 tacgtttagg tgctgacgat tacctaacaa aaccgttcag cataaacgaa cttatggctc
     3421 gtgtcaattc tcttattcgt cggtatacta tgttaaaccc tgcttttata acagacacag
     3481 attgcataat aataaatggc atgattattg acaagacaaa ccgaattgtt tctgtcaata
     3541 atattcctgt tcaacttaca agcaaagaat ttgatttact tgcttttctg gcttctaata
     3601 agggacgggt gtttaccaaa aaacagattt atacacaagt atgggaagaa gaatatgctt
     3661 ttgacgatag taacatcatg tctttcatca gtaaattgag aaaaaagatt gaaccagacc
     3721 ccaaccatcc attttatatt ttgacagttc gtggtgtcgg ttatcgtttt aataaggagg
     3781 cttaacatga atacaagtgt ctatctgctt ttgatattgg ttcttagcct gattattata
     3841 gcgtaccttg tttctgtcct gctacgtgtc cgaatacaac ttacacttat aaaagatgct
     3901 ttagaggata taaaaaatgg aaaccttaat cgacgtattt taacagatga aaacgacatt
     3961 acaaaacaaa tttgctatga tattaacgaa atagcaatca atagccaatt tcaacttatt
     4021 cagcaaaaac aatcagaaca agcctacaaa cagctaatga caagtctctc ccatgatgta
     4081 aaaactccac ttgcttcttt ggtcggttat ttggaagcag tagaaagtaa aattgttgta
     4141 ggagaggaaa aagacgagta tatccatgtt gcgtctaata aggctcatta cttaaagaat
     4201 tttgtagaaa atctatttga atgggtaaaa ttggattcta aggaacaagt ttttcatttt
     4261 gatatttttg acttgaatga attatcccgt aatattatat ctgattggat acctgtttta
     4321 gaaagcagtc attttgaata tgaatttgat ataccagaaa tagagtactt cttacgtata
     4381 gacgcaaatg catatacccg tatcattaat aacctattac aaaatattat tacccatagt
     4441 agtggcaaca aaatgacatt gagaattttt gaaaacaaag agcaagctca aattataata
     4501 acagataatg ggaaaggtat atcttcagac aatctcccac atatttttga aaggttgtac
     4561 caatgcgacc attcacgagc ttcaaaggga aatggtttag gcttggcgat tgcaaaggaa
     4621 cttattaacg ctcataaggg aaatattacc gccaacagca ctcccggtat gggaacagaa
     4681 tttacaatat tgcttcctaa agccctgtaa aagtacgagg ctttcttact ctaaaacaag
     4741 ataaaagcaa gattatggca aggttttggc aaggttcatg ttttataatt ctaattgtag
     4801 ttgattttga cgttgtatca actatctttt gtagaaacaa atttattaaa agtgaggaaa
     4861 ttatatatga atgattttgt gattgaaaca aagcaactta caaaaattta tgggaatcaa
     4921 acagtagttg acaaagtcaa tctccatgta aaaaaaggcc gaatatatgg tctgttagga
     4981 cgcaacggag ctgggaaaac cacaattatg aaaatgattt taggattgac ttcaatcacg
     5041 tatggcgagg tagatgtatt tggagagaat attaagggac gtgaaaaaca ggtatatccc
     5101 cgtatcggtg caattatcga aacgccagga ttttatccta atctgacagg aacggagaac
     5161 ttggagattt ttgcaaaact gcgtggtaca gccgccccta attctgtaaa aagagcattg
     5221 gaaattgtag gcttacctta taaaaataaa aagctgttta gtaaatattc acttggcatg
     5281 aaacagcgac ttggtattgc caacgctatc ctgcatgacc cagaactgtt agttttagat
     5341 gagccaacca atggtcttga ccctattggt attgcggaga tgagaaagtt tattagggac
     5401 ttgagcgttg agcatggaaa gacaattctt atttccagtc atattctttc agaaatctca
     5461 ttgttggctg atgatattgg aattatcgac cacggtgttc ttttggaaga aagtagtatg
     5521 agtgaactag aaaagaaaaa cagtaaatat atcctgctac aagtttcaga tattccgaag
     5581 acatcactta ttttagagcg tcaatttaac acgaaggatt attccgttca agatgactac
     5641 acgttacacc tttataacac taatctggat atgggtgaaa tcaataaagc acttgtaatg
     5701 cagaatgtaa ttgttattag ttctcaactt tgtaatgata ctttagagga ctactttaaa
     5761 aaaatcacag gaggagaggg cattgcttaa acttattcaa acagaatttc ttaaactgcg
     5821 tcgtaggaaa cttatttggc tgatgttgtt gtctgctctc attatgccgt ttttcgcact
     5881 actatacttc aattattttg gtaaaacagg tgttgagcca acaaagtttt ataaatggtc
     5941 tgcatttggt tatacacttt ggattatttt gcccgttgtt ttgggtatat tttgcaccat
     6001 gcttatacac gaagaaaacc agtatgatat gctcaaacag ctttggattg tacctattag
     6061 taaaatggga tactttttta gtaaattttt cgttgttttg atttactcta tttgttttat
     6121 gctgattaca gccgttgctt ctgtgttatt tagtgtactt tctggatatg tcgtatttag
     6181 ctgggcaagc attttatatt tgttgaaaaa atgtctagaa attggtgtaa tcactgcttt
     6241 tgtaatgttg ccgattttgg caatcgctac atctcaaaaa ggatacattc tcccaatttg
     6301 tatcacattg gtatatgcct tttccggttt tgttataatg acaataaata tgtatttaca
     6361 ccctttatcc agtatgggag ttattatcat gagaaataaa gacattccag gtcttatatt
     6421 ttcacaggaa attaatgtcc cattagcatt tctttgtatt tgtatttgga gtattgtatc
     6481 agtattgttt gcaaacattg cactaggaag aagaaagtga ggtgtagata atgtggaaat
     6541 tactttgggc tgaatgtcaa aaaattcgtc gttcaaaaat tgtttggatt acagtttttg
     6601 catccattat gatagcagtc atagtttttg caggagggca ggatgtatat aatgacccag
     6661 atttacatta tggcttaaag agcgtttatg acggttcacg gtatatagac aatgcaggtt
     6721 ggtatatgga cgcagtacaa ccttggtcaa ctttttttgt tcttcctgct gtcattgcct
     6781 tattaggaag ctatattatt tgtcgtgaag aagaggagga cactattaaa tccctgcgtc
     6841 ttattcccat aaatgaaaca aatttaacca tagcaaaaat gattattact tttatattca
     6901 gtatacttct ttatttgtta ctctttacta taacattttt gactgaatcc gttttacatt
     6961 tttccgattt atcgacaaaa ctggttttaa gttgcatgaa agagtatttt cttgatggca
     7021 taggtgtatt ctttgcaatt tctcccatta ttgccttggt atcgcgcatg aaaaaaggat
     7081 attggcttgc attagtattc acagaagttt attctattgc tggactattt gcgggtatgt
     7141 caaatgtctt acaaaccttt tttcctattg cggcaatatt taatatttct ggatactata
     7201 taactactgg agaaaaaatt atggggagta tcataagttt attactttgt gcctgccttt
     7261 ctgcatttat actgaaaggg ctaaaacaca atgaaaaaaa ttgaaatatg tatatcaaaa
     7321 tgaaaaagat aaaaaaactg attattctaa ttgtattctt gtttcttttt ggcatgttac
     7381 actgttatac tgaatggaaa ttcaacaatg acccacctaa aggggtaata gaaagaataa
     7441 atgagtggac tgataagatt ggactggatt agtaacttat gttaattata gtgaatgtaa
     7501 tattagcaag ttattgtttc gtattttaat actataactt taaatatttg gttttaatct
     7561 tccaaacgaa tataaaaaaa ctgtcacaga ggcaacatat ttttgaatat ttataaagtg
     7621 gtagttttga ttttcaaagc tgccgccttt tcttctatat aagcaaactt atcctcaaca
     7681 aagtgtaaaa catggtacat tttaagaaaa aagtaccaca gacacaagca ataaaagaaa
     7741 cgccgagaac ctacaaaaac gtagtgctta tgcagattta cgacgccttc tattttctca
     7801 accgtcttaa tgaccttgta caaaagaaat ttttctaata ttttttataa tcttatcttg
     7861 tgatgttttt tatgtataaa tgacttaata acaaatccaa taaaaattat ggatattggt
     7921 ataattagaa cgaggaattt ataatcatta taatgtgaca ttattcttac ccaactctca
     7981 gaaaaaatat atcctatact gattaatgaa gtattccata tggttattcc cacgatagat
     8041 gatattgcaa aagttataat attttgacct gctatacctg ctataaaaga tatgtatgtt
     8101 ctacataaag ggattaatct acatacacaa acagaaatag aagagtattt attaaaataa
     8161 tcttgagatg caaatattcc tttctttgcc tttggacata tctctattat tttatttatg
     8221 atagatttac ctccccaatt tcccactgta taacaaaata tcgaaccaag tatacctgca
     8281 attatactta aaattaaaat tgtcagaaat ccaaaatgat ttcttgcagc aattgctcca
     8341 cataaaggta aaacaacttc gctaggtaat ggaaaacaag catactcaat cataattaat
     8401 acaaatacag agattaatcc atattgtaaa ataaaactat tgattacaga cacttactta
     8461 tctatctcct ttcttattta aaggttttaa gggtacatat tctaaggatt ctcaccctat
     8521 atttaaagaa tcaatctctt taaactatta tatgtattta cacaaagcat ttataacata
     8581 ctttaaaaat agtaccttaa aataagaaac ttaataaata aaaaaa
//
LOCUS       DAEOTL010000132         8526 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEOTL010000132 DAEOTL010000000
VERSION     DAEOTL010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.134"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(240..1109)
                     /locus_tag="KRH82_003644"
     CDS             complement(240..1109)
                     /locus_tag="KRH82_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8656894.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(1206..2063)
                     /locus_tag="KRH82_003645"
     CDS             complement(1206..2063)
                     /locus_tag="KRH82_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8656895.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(2278..4296)
                     /locus_tag="KRH82_003646"
     CDS             complement(2278..4296)
                     /locus_tag="KRH82_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBG8656896.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            complement(4567..5343)
                     /locus_tag="KRH82_003647"
     CDS             complement(4567..5343)
                     /locus_tag="KRH82_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBG8656897.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            complement(5400..6371)
                     /gene="asrC"
                     /locus_tag="KRH82_003648"
     CDS             complement(5400..6371)
                     /gene="asrC"
                     /locus_tag="KRH82_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBG8656898.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEDINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKKPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            complement(6384..7175)
                     /gene="asrB"
                     /locus_tag="KRH82_003649"
     CDS             complement(6384..7175)
                     /gene="asrB"
                     /locus_tag="KRH82_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBG8656899.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            complement(7176..8183)
                     /gene="asrA"
                     /locus_tag="KRH82_003650"
     CDS             complement(7176..8183)
                     /gene="asrA"
                     /locus_tag="KRH82_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBG8656900.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDLKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
BASE COUNT         2771 a         1525 c          762 g         3468 t
ORIGIN      
        1 aataaaaagt tactttactt tttattattt aaattcctgt ttttattata ataggtaaaa
       61 ttctattaaa ctagttcaca ttttcattat tattgatata ttatatatga atataccatt
      121 ttgtttttta ataaaaaaat catgctacat caatagtaag caactattaa tgtagcatga
      181 ttttttgtat ctaaataatc ttagtattta cctatcaata tagattgata tatcaaaaac
      241 tatagtcttc tatattcttc tctttttagc ttttggttac ttagatagta atcaatttca
      301 tcaattaaac gttgtttatc atcaggtaat acacctttta aattagcata atttgatgca
      361 tgattacttc taaatacaat tttttcatta gcatctatat tctttatcat ctctttaatt
      421 tcttgtaaca cagccttatc ctctagtatt gtaaactctc ctgccttaag taaatcgtaa
      481 agttcagtat taggttctac cattaaacta agtacaccca cataatctgg tgaaattgct
      541 cctaacattt ttcctgtatc aactgcatgc tgatgtgttt ttttagttcc tccaagacct
      601 gctattacag tggctgataa tttaatccca ctttttttaa cttttctacc aacttttatt
      661 aattgttcac tactaaaacc tttcttaata tcttctaata cttcattgct tccactttca
      721 agccctagat aaatcatttt aacaccaagt tttcttaatt ctttaagttc atcatcagat
      781 tttttctcta tagatttagg agagccgtac atagtaattc tttcacactc tggaaaaact
      841 tcttttatat ataaaataat atctcttaat ttctccattg gtattatcaa tgcatctcca
      901 tctgctaaga atattctttc tacatgctta taatatcttc taaatatatc aatttcattt
      961 tttattactt ctagtggctt tattttaaat tttttagatt tgtacatact acaaaacgta
     1021 catttgttat gagaacatcc tagtgtgact tgtattataa gactataagc ctcacttggt
     1081 ggtctgtaaa gtggcatatc gtattccata ttaaaatccc ccttgtaata aaatattcat
     1141 tctattatat tattaatatt tactttaaat aataacttat aaaattatat tttttaaatt
     1201 ttagtttaag atatattctt taaaaattta atgatactat tggcagtaat attaagttgt
     1261 ttttcttgac ttataatagc atcattatct cccttttgtt ttccataatc tccaaattgt
     1321 gcatgatttc ctccttcaat ctcaacataa gttgtatcat caggaagttt ttgttttgat
     1381 tctacaagac ttttaaaatt gactactcca tctttgctcc cccatataga tataactttt
     1441 tttcctaatt ctttcaactc atcacccatt ggataagaag ctaaaaatac aacgccttca
     1501 attaatttat tatcacgtgc aaaatttgat gctgcaactc ctcctaatga atgacctcct
     1561 attacccaat gttctatgtt gttgtaagaa tccataactt tctgtgcctt attagttcca
     1621 agtatagcta gattaagtgg catctttacg attacaacct catatccact ttctgctatt
     1681 tttcttgcaa gtggagcata agattctatt tctactttag ctcctggata caaaattaaa
     1741 cctttagaaa cttttcttcc ttttggtgta aatgaaatgt tttcatttac agttacttca
     1801 actttactat tgctgactag agcttctttt gccagctttt gaggttcata tgttttattt
     1861 atccatatga aaaagccaag caaaatcaat acaaatagta tacctattcc cttaaatatc
     1921 ttattcttta tgttaaattt tctattatta tttttatcat ctttgttctc aacctcatca
     1981 taaagtaaag gtctctcaag ttccatagtt atactaaatg tatcatattt cttattacgc
     2041 tttaccttta catctttact cataaatcta acccccataa tatttgaata ctattatagt
     2101 ttatcctaag taaattgttt tttcaaccaa tgaaaaaaat caatatttta actattttca
     2161 tataaaattc ataaatatat gttttttgtt ttttatatat tattttcttt tagtatttta
     2221 taaaacaaat agccatatac tttattttaa atatatggct attctataat ttaatatcta
     2281 agctgcttct tttattgaaa ctttagttat attacttatt ctatacattt ctttgacacc
     2341 atttagagtt tgcagtaagt ttagacatat tatcttgtca cctagacttt tagtatttac
     2401 aatactctct aaaattacac ttcttccttc atcatactta tctacattgt aatttgaaat
     2461 ataattagta tctctcaata ttttttcaac atcttcatct tttattttat ttttattaac
     2521 atttatatat agattataca tattacttat tagtaatttc tgattttcta aaaaatcctc
     2581 ttgatgttta tctttatata tagcatttat caacataagt ctatcttcaa taagtgatgg
     2641 tatcaataat aaatttttta tatagtaaac atcagctaca ttttctatag acttattgac
     2701 ttcatcaatt atatttttaa ctattccttt atacatttct ataacatgtt gatagcctgt
     2761 tttagcatca tatggtaata taaacttatt tactattaat gcaataattg ctcctaatgc
     2821 tacatatgaa atcctgctta tggttaaaac atttgggtct cccataacta ctgctgaacc
     2881 aagagctgaa acagttacac ataccattaa ttttctataa tcaaccacat aagagtttat
     2941 ataccctgct aaaagaacta ttaacgacct taatgtacta tcttttatta ttgaaaataa
     3001 tacaataaat attacagctc ctataaatgt accttctatt ctttttctag acctttgtat
     3061 acaattttct gcgtaaggtt gtgttaatga aaagacagtt aacattatcc atcttccatc
     3121 tcttaaatgg aaataatcca taataaaacc cgctacagct gtagctaaag caatctttac
     3181 tgcataagaa aatcttatag aatttaaatt aaagtttttc ttatatattg atagtcgttt
     3241 aaattcatga ggtatctttg attttctttc agctttcttt tcgtctcttg attttacttt
     3301 tttataatct actaaaaact catataaatt ttctaaaaca ctataaattt cttttaaatt
     3361 tatattttta gtatcctgag caataacata atctctaaat cctaatatct ctttatcagt
     3421 tatggtatct ttattttcta aacacatctt aatatagttt atttctttcg ttgctacaac
     3481 taaaacatct gatttactat ttatgctact ttcttctaaa atatttttta tatcttcatc
     3541 ttcaaattct ttactatcct ttttgtatct ttccaggatt aaacttattc tttctaatga
     3601 aaataaaata ttcattatgt ctatacctct aatactgata taaaagtcat cttttctatt
     3661 atcaaaaata accattttca aatttttaga tatagaattt attctataat tacagctatc
     3721 tatttttctc atactagatt taattataga actatcatca ttaatagtat tttttaaaag
     3781 actaattttt tctaataatt catcacatat agatatcagt tctttatctc cgacattttt
     3841 catcctattt ctattcataa caaattgagc aatcattatt ataactgctc caacagctaa
     3901 agccgacaat ctcataggaa attcactttt tcctacaggt atacttacca taaatatata
     3961 cattagacca aaaggtacat atactgctct ttttaagtca taactaaata cataccctat
     4021 tataaataat gctataaaat ttaataaaac tcctaaatac atattttgta ctgcaaaaaa
     4081 tgatagtatt cctaagatta tatttattgc taaatacttc agtaaatttt taattggaga
     4141 aatagttaaa tctctttcca agagtgttag catagctgtt actataccta cacctataag
     4201 tgtattttta cttccaaata aatatataaa tatagaaata aatgctatta taaaaataaa
     4261 caactttgtt tttgatatta ctagtttctt tgtcatcata tcccccctaa aaatttcaac
     4321 aagaccaatt ttatcatatt tgttatctta ttcaaaatgc gcttttttac ggtaggactt
     4381 taactttttt tatatttaga actatataat tcatatataa acgtattttt tatatatata
     4441 accgatatat tttcgtatgc tcccatattt tttttgtttc aaatattttt tcaaaaatat
     4501 aaaaataact ctctcaataa tactaaaaat gcatttatca agagagttat aatttataca
     4561 ataaatttaa ttaagctttt ctttacctaa tatataagtt ccaagaccca taaataaagc
     4621 tcctccaaca atatttccaa gtgttacagc tactaaatta taaatagctc ctccaatagt
     4681 aactgtactt attgttggtg aaaataatga aacactataa attgtcatat ttgctacact
     4741 atgctcaaag cctgatgtta taaaagcaaa taaacataag aatatcataa ttatttttgc
     4801 agtatcacta ttagttctaa acgaacacaa cactgataca catactagaa tattacataa
     4861 aatccctcta aagaaaagag ctgtaaatgg catggatgct ttactagctg ctgtatttgc
     4921 aaaaaattca gctacaggtc ctttgtctac tagaccagtt cctacaaata taatgcctaa
     4981 aaccaaagct ccgattaaat tacctaccca actgtatgcc catattttag aagtatcttt
     5041 tatacttaca cctttattta acataccagc agacataacc atattgtttc cagtaaataa
     5101 ctctgttccc gtcattataa ccaaacttag tgctattgca aatgataacc ccattactat
     5161 cttagtcata ggtgaacctg catcagtcaa aagtcctcca atagtaaata tcaaaagtat
     5221 acctatacct acataaagtc ctgcaaacgc agaagatacc aaatatttta ctttacttgt
     5281 gtttaataaa tttatcttat ttatagctgc attagttaat ttatccaaag tttctttatg
     5341 cataattccc tcttccttct attaaatttt aatttattca aatatatgtt ttactcaatt
     5401 tatagatatt taattccact ccagtatatg ttttcgtaca ttttagttat ttctggaagc
     5461 tctacacctt caagtgccca ttttttaaat tccataaatc ctgttctatc aattatatat
     5521 cctatatgtt cttttcctcc tggtgcatct ttatctatat acttttctac atatctataa
     5581 gtattaagta ttatctttat tatgctgtcc tcatctaccc ataaaagaaa atcttctgct
     5641 agtctaggtt ttttctttcc tgttctaccc attatagcta atctatagta ttttttctca
     5701 tctctagtcc atgcatttgt tgggcaattt agtacacact ctccacagcc tatacactta
     5761 tctttatctc ttaccacctt attattttct gtttttaatg ctccaacaga tatcttagaa
     5821 cattttttta cacatgctcc acaatttaca catctatcct tttcatatat tggtaaagcc
     5881 ataccaataa ttccaaagtc attcattcta gcttttatac aatcatttgg acaaccagtt
     5941 aaagccactt taaaatgtaa atcatttgga aatatagctt tttctattct tttagcaaat
     6001 tcagttgtat tatattgagc ctttggacag actttatttc ctatacaagc tgctatattt
     6061 cttgtacctg ccgctggata acctgcgttt ttctcacttt gatttatatt cattttttca
     6121 ataacaggtt gtataatttt atttatatct tccatatctt ccatatttat tcctaatatt
     6181 tcaaacccct gtcttgtagt tatgtgcacc tgtccattgc cgtactcact tgcaatttta
     6241 gaaactatag ctaaactttc agggtcaata agaccaccag gtactctaac tcttaaagaa
     6301 gtctcatatt ttgtttttgt aattctataa gcatttttca ttactttttt ggtatttaaa
     6361 tctcttatca caaacttcac cccctaatca ataagatttt tagcatatga ataatcaaat
     6421 actggtccat ctaaacatat gtaagtatca tccattttac aatgtccaca tttacctatt
     6481 ccacaacaca tttttctttc ataagaaacc caaatgttct tttcatctaa atctcttttt
     6541 aaaaattctt ctactgtaaa tttcatcatc attggaggtc caactacaac tatagaagta
     6601 ttgtttatat ctttcatatc caattctggt atgtattttg ttactaatcc tacattacca
     6661 ctatatcctt cctctgctcc atctacagta actaaaatat caagtttttt actccatctc
     6721 tttaaatcat ctgcaaataa aatatctttt ggtgatttaa atcctactat taatttaaac
     6781 ttttcgcatt tttctttatt attataaaaa tattcaacta ttcctcttac aggggctaat
     6841 gcacttcctc ctgccactac tacaatttct cttccttcat aaagggatac atcaaatcca
     6901 tttccataag gacctcttat aaaaaaagaa tctccttctt tataattaaa caactcgcta
     6961 gttacttttc ctacatttct tattgtaaag tcaatataat cctctccata tcctgatact
     7021 gatattggac tttcaccgta tttaggtata gatatctcat aaaactttcc aggcaataca
     7081 ccttttgtat tgcagtttac tctaaaagtc cattctttat cagtatgttt aactatatct
     7141 agtatttttg cacttactgg tatatatggg ttcatttata cttcctcctt actaattact
     7201 aaatcattta ttttttctat acactttgaa aatgatatgt attgcggaca ggcatcatca
     7261 catcttccac agccaacaca catatgatat ccgaatcttt ttttaaaatc atgtatttta
     7321 tgcatagttt taaatctcat tctttcgcct tgtttttttc taaaagaatt tccacctgct
     7381 atatctgtat atccatctac ttgacaagaa gcccaaaccc ttcttctctc acctacattt
     7441 tcgttttcct tatagaaaat atcctgcatt gtaaaacatg aacatgttgg acatacaaaa
     7501 ttacatctac cacatcctat acatcttgta tcatattcat cccatattga atttcctatc
     7561 atttcatttg aatcaatatt ctctggcaca tctacagata ttaaattatc agttacataa
     7621 tcaacattaa attcagttgc ttctccatta aatacttcaa attcactatc ctttaaatct
     7681 aagtacagtg tatctccttc tatatttaat ccaattgaat aattatcagt tttgttagaa
     7741 tccatgctca cacaaaaaca gtttctaaaa ctttccttac accctacaag tgcaaacttt
     7801 actttatctc tgatattttt ataaaaataa tctttttctt caccattatt tagatatatt
     7861 tcatcaagtc tttttatacc atttatgtca caagctctta agaaaattaa aattttcttg
     7921 ttgtctaaat cgctttcctt aaactctttt tcagtaaaat aaaacaatac ttgatttatg
     7981 ggaagtacaa cttcttttgg tgaaaagttt gctttcttag caaattccat ttcttcaaaa
     8041 gcgtttacct ccttgtatct tataacatca gtatctgaaa aagtaccttt aaatgggatt
     8101 aaaactggtg caaatatctt gtagtctttt tttagataat tcagaccttc attgaactta
     8161 gatgaatcta attttagttt catttttatc acctttctta tattttagtt ttacttactt
     8221 gctatcttgt ttaaatctta acactttatt ttctatgctt ccgtgataat tatcacagtt
     8281 tcaaaaataa taaaaaaaat attaatggag tttattaagt tctgttaata tttttttatt
     8341 atctacatta ttcaatttca aatctaatca cttaaataca atcattaagt acaataaaac
     8401 tactatctac tcaatttttt gaataaaaaa gaatcttatt tgttttttta tacaattcaa
     8461 tagggtaaaa taaaaattaa taaattagac aataaaaaag aatctataaa tagattctct
     8521 taataa
//
LOCUS       DAEOTL010000133         8458 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEOTL010000133 DAEOTL010000000
VERSION     DAEOTL010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.135"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(212..736)
                     /locus_tag="KRH82_003651"
     CDS             complement(212..736)
                     /locus_tag="KRH82_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBG8656901.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(801..1553)
                     /locus_tag="KRH82_003652"
     CDS             complement(801..1553)
                     /locus_tag="KRH82_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBG8656902.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1584..2882)
                     /locus_tag="KRH82_003653"
     CDS             complement(1584..2882)
                     /locus_tag="KRH82_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBG8656903.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEDIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMDDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINVSQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2899..5163)
                     /locus_tag="KRH82_003654"
     CDS             complement(2899..5163)
                     /locus_tag="KRH82_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBG8656904.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5418..6236)
                     /locus_tag="KRH82_003655"
     CDS             complement(5418..6236)
                     /locus_tag="KRH82_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBG8656905.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6229..6927)
                     /gene="cbiQ"
                     /locus_tag="KRH82_003656"
     CDS             complement(6229..6927)
                     /gene="cbiQ"
                     /locus_tag="KRH82_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBG8656906.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6930..7214)
                     /locus_tag="KRH82_003657"
     CDS             complement(6930..7214)
                     /locus_tag="KRH82_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8656907.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7204..7956)
                     /locus_tag="KRH82_003658"
     CDS             complement(7204..7956)
                     /locus_tag="KRH82_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBG8656908.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8138..8330)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
BASE COUNT         2662 a         1527 c          904 g         3365 t
ORIGIN      
        1 ataaatatat aaacaatcat aataaaattt ttttaataaa actttatttt ttagttaaaa
       61 tcatacaata tatagatttc cacaatacaa ataaattaaa aagtgaaatg tatttgtcta
      121 aaaacataat aacatttcac tttatcctca tttttaagta atatatattt ttaattttta
      181 tttataacta aatctagttt ttatataaat tttagttttt ttctacatct gagtaatcta
      241 ttccaaaagt ttctacagta acagatttca taacttgtgg agtttgtggc ttatcagctg
      301 aatctgttct aactgatgct atttcatcaa ctgtatccat accttctatc actctaccaa
      361 aacctgcata ctgaccatct aagtgtggtg agtttttatg cattatgaaa aattgagaac
      421 cagctgaatt aggtgccata gttctagcca ttgatatgac tcctctttca tgttttaaat
      481 tgttagtaaa tccattacca ctaaattcac cttttattga gtgacctgga ccacccattc
      541 ctgtaccatt tgggcatcct ccttgtatca taaatcctgg tattactcta tgaaatatta
      601 ttccattgta atatccttca tttactaatg atacaaagtt tttaactgta tttggagcta
      661 tatttggata taactcaatt ttgatttctt ttccattttc catttctata gttactatag
      721 gatttttatt ttccataatt tattaccttc cttttcatta gttaaattac ataattacat
      781 ttattatatt atactctaaa ttaaagtcta tcaagtatat tttttcctat ttcatatcct
      841 tcttgataaa tagttttaca aaactcatca tcaaagttaa gcgtgtcttt aggagcaaat
      901 tgagtattag gtctaactac tattatttta tcttcatcat atactttttt aatatcttct
      961 ggcaactcat aattatattt tgtggatatt aaaataattt tatccacatt atccccaatt
     1021 aatggttcaa ttaatgcact cctaattaaa cctccatcta atttgaaacc atcataaatt
     1081 ccttcttgca catctttcac aaattgttct ttaaatccaa gagttgcgtt tggatttgat
     1141 ggtaacaacc cactgtatga aatgctgata atggcttcat tacgaggcat ttttgatacg
     1201 tcaacaatct tttctgatac tactttatta tcaacttcaa cataattaac ataaaagttc
     1261 atttcttcta tattactatc atctagttcc cttaggttgt ctatagcagg agaattatcc
     1321 acagtattat ttactatttt tacatttcca ttctggatat cttttatatt tgtccacatt
     1381 ttctccaagt tatcaacatt ccctgtgtac aaataatatc catttattgc tcctattgat
     1441 gtccctgaaa tcgaataaaa tttatttatt cctccatcat acaaggcttt aactactcct
     1501 gcttgataag ccccttttgc tcctccacct tctaaacata atcctaattt catagtctca
     1561 tctccaaatt gtttatctta tatttatatt tcaaaaaact tactaaatgt tttatatata
     1621 ctatagtggt cctcaacatt tcctaattct cttatagaat gcattgctaa aattggactt
     1681 cccacatcca cagatggtat atctatatga gtagaagata ttggacctat agtacttcct
     1741 cctctttcat ctgacctatt aacaaattct tgatactcaa cattagcttc tctacatata
     1801 tttttataaa tagctataga atatccatca ctagtatatg cctgactaac atttatcttt
     1861 ataaccggac cttttcccat tattggttta ttagttgggt catgcttttc tggaatgttt
     1921 ggatgaatag catgagctaa atctgatgat atcataaaag atgaataaat agactcaaag
     1981 aatccctctc tatccttacc cattgatatg caaattctct ccaatatatt taacaacatg
     2041 tttgaatctg caccttgttt agtagagcta ccaacttctt cattgtcaaa tacagccatt
     2101 acatttacac catgttgacc tttagtatta acaagagcat tcaaactagc atgtaccatt
     2161 gcaagattat cttgtctccc aatagatata aattcatcat tagcccctat taaacttcct
     2221 ttttcaaatt catataaaaa taaatcaaaa tctataatat cgtccatatt tacatctaag
     2281 ttagatgcta tttgctttat aagaaaatta tctttttcta atgtatcatt taacatccca
     2341 actaaaggta acatatcttt ttgcttatta tatgaatgac catcatttat acttctattt
     2401 aaatgtattg ctagatttgg tattatacaa attggctttt taaagtctat aagcctttca
     2461 tttggtttta atatactatc accttttaaa actactctac cagctatccc aagaggtcta
     2521 tccaaccatg tacttaatat tgctcctcca tagcattctg tatttaactt caaataagat
     2581 ttttcagctt ctatttctgc atttggttta atactaaatg taggagaatc tgaatgagag
     2641 cctattattc taaatccatc tctttctata tcttctgaat ttactacaaa agctactata
     2701 gctgataaat tcttagtaac ataatacttt ccaccaactc ttagattcca tctttgattc
     2761 aaaactaatt cttcaaatcc atttttatct aagatttcct tagtactctc gactgcatga
     2821 aaagacgacg gactatcata tatgaagtct attaagtttt tagcaaagtt tatactatcc
     2881 attcctcatt tacctccatt ataaaatatt tagtgttgta tattctttat ttattttttt
     2941 aattccctgt tggtcaaaag ctatagtaac atctgtacca attatagaaa ccactgtccc
     3001 aaccccaaat ttaggatgat gtaccttaga accaagtttt atatcatctg gattagtttc
     3061 tttattagaa tcttttattg tagcattaac tttatctgca actttagatt tgcttatagt
     3121 actcatatac tttttagtat atttatctaa catattataa cttgctttag aatagcttag
     3181 ttcttttttt actttgtaca atctttctat acattcttct ggcagttctt ccataaatct
     3241 tgaagctatt gcaacatttg ttttaccata taatgttctc ttctctgtca atgacatata
     3301 tagctcttct ttagctctag ttataccaac ataacaaagt cttctctctt cttctatttg
     3361 tgaatcactc atagatttta tagctcttga tataggaaat aacccttctt ccatacctgt
     3421 taaaaacaca acagggaact ctaaaccttt ggatgtatga attgtcataa gcgaaaccct
     3481 atcattgtct tcttcatcat ttgattcaga tgtaagtgct atacttgtta ggaatgtctc
     3541 taagtcttta ttttcataag tatcatcatt actactttca aactccaaag ctatagaaat
     3601 aaattctctc aaattatcaa ttctgtcttg agcttcttca cctttgcctg ttaaatcttt
     3661 ttcattttta tttcttatct ctacaagctc gtccatatat cctgtagtat ccaagacttt
     3721 ttctataagt ttgctaacag gataaacttc ttttatagtt ctaagagtcc ctataatatc
     3781 aacaaatcca cttatacttg cccttgcctt agtagatata tctgaatttg tttctatatc
     3841 aattaatact gagtatatac tttcctgttt taagttagct ctatcttcaa ttttttctat
     3901 agttctaagc cctatacctc ttctaggaac atttataatc ctttttatag atatatcatc
     3961 ttgtggattt tgaataactc ttaaatacgc caacaaatcc tttatttctt ttctctcata
     4021 gaattttgta ccaccatata tattgtatgg aatttgactt ctatttaaag cgtcctctac
     4081 aggtcttgcc tgtgcatttg ctctataaag tactgcaaaa tccttataag gtctattttc
     4141 ttttctagct atttgtgcaa ttgaatcagc aatgaaatca gcctcttcta tttcgctacc
     4201 agttaattgt atctttataa gttctccttc ttttttttca ctccaaagct tttttctttt
     4261 tctttctata ttattagata tgactttatt agctgcatct aatatcactt gtgtagacct
     4321 ataattttgt tctaacttta caacatgtac attgtcataa tctttctcaa attcaagtat
     4381 gtttcttata tctgcacctc tccatccata aatactttgg tcatcatctc caacaacaca
     4441 aatattttga tgttctcttg ctaataattt tatcaattca tattgagctt tacttgtatc
     4501 ttggtactca tctaccatta tgtatctaaa tctacttctg taatatgcta acacttcatc
     4561 attagccttg aaaagttcta cagttttaag tattaaatca tcaaagtcaa gtgcactatt
     4621 tctttttaaa cggtcttgat atagcgcata aatatctgca atcttaacca ttctattatc
     4681 tgccatattg atatctttaa actgctttgg agtataaagt ttgtcttttg ctcctgaaat
     4741 tgcacttata actgcttttg gttcaaacac tttatcactt aaatttaatt cttttagaca
     4801 gtctttaacc aatgtaactt ggtctgctga atcataaatt acaaaacttc tattgtaacc
     4861 aatcttattt atatcttttc ttagtatacg aacacagcaa gaatggaatg tacttatcca
     4921 catatcctta gtttcaggac ctatattttg ttcaactctc tctctcattt catttgcagc
     4981 tttgtttgta aatgttatag ccaatatatt tggtgcttgt acacctttat cttctataag
     5041 atatgctatt cttgttgtta ataccttagt tttacctgaa ccagcaccag ccagtataag
     5101 tactggacct tcagtctttt ctactgcttc tctttgagca ggatttaatg tatctaaatt
     5161 catatttctc ctcctgttaa cagccataaa tatattttaa tctaaaatat gaattacttc
     5221 aaattataat tatgtattat attaatagat tatttccaat atattacaat taaataacat
     5281 ttttccatat aatttatttc attgtttaat aaaaaaaata accttatgat ttggggaatc
     5341 ataaggcacc tttaaggggt ctaggttaag ggttattata tataaatcta tttttttaaa
     5401 ataggtttag ggcttaatta tttatttgta ttaagttctc tttccttcca atacttatac
     5461 aaatcttctt ctttcttaaa taagggtaaa ttcatatttc tatgtacttt tactaaccat
     5521 ggggattcta gaccagcttg tataatatta ttttcattta taaacacatt ttctgccttt
     5581 ccttcatcaa tcaaaatccc cttatccaat acatatatgt aatcacatat ttcatacatt
     5641 aaattcatat catgactgga tattactatt tttatattat ttttatttaa tccctttatt
     5701 atatctacaa tagacctagt acttactggg tctaaaccag ctgtaggttc atcaagtaat
     5761 acaatttcat tttccattgc tataactgat gctattgcca ctcttttttt ctgtccatag
     5821 ctaagaaaat gtactggcct gtctataaaa tctattccat taacagctac tagagctttg
     5881 tttattctct ctttaattgt tttttcatcc ataccaatgt ttctcattgc aaaggctata
     5941 tcatcatata cttttgaata aaaaatttgt ttttctgggt cttggaacac aatacctaca
     6001 ttttttctaa ggttgtataa acttctctta tcatatttta acttttcttc tttaaaaaga
     6061 atttctccag atgtaggctt taatataccc attaaattca taaataatgt tgattttcct
     6121 gaaccatttg aacctattat acctataaca tttccctttg aaaaatccat attaatgttt
     6181 aatagtgcat tggtattttt ttcatattga tacgttaaat tatttatttt aaacatcatt
     6241 atcccctact atgtgaaatt taccatcata caattttatg tctaatgata tacacatatc
     6301 atcatacctt gtcataagtc ttttgtacag catacttcca agaataccta aggatttata
     6361 tgaagttttt aaatttatat atccaaatct tagctcttgt gacttgtata tttctgaaaa
     6421 ttcttctaaa aatatgaata taaacctata tattaacatt gataactcga caaaagtgtc
     6481 aggtaaatga agttttttaa aaaagaatat taattgatta aaaggtgttg taagtataca
     6541 aaaatacaca caagtcaaac aagacatcgc tctaaataac acatgaatag acatgtcaat
     6601 agacgccttt gatattccta cattaaaact aaaaaattca aaactatata ataaatctgc
     6661 tttattaaaa gatatattta caagagttat tcctatacta agaaataaaa agtacattgg
     6721 tattctaagt aattttaaat aattttttaa atctattcca gccacacaaa caaccaaaat
     6781 actcattaaa atcataattc cacttaaaat aaatatattt tgtattacca tagaagcaat
     6841 cagaaaaatt actcctatgg ctactttttt gtttggattt actttactca atctatttgt
     6901 atatgcatat ttatcaatta taagcatgat taacttctct ttcctttttg aagacctaat
     6961 atgtatccta ttacaccagc ccctaaagct gcttgtgcag agaataataa actttctatt
     7021 tctccacttg gtggctcata tggactgcta aaccatggtt tgtaatttgg atttatctta
     7081 gtaatttcac tttcagcttg accatctgct cctccatatt cagcacctga gttgacaagt
     7141 aatgggaata taataagagc tactactaat aaaagtaata atatgttagt ttttgttttt
     7201 gttttagcac tcattagctt taactccttt atcattattt tctagtatgc ttttttctcc
     7261 gttttctgta attaaattat atacaattac agtaagtata ccttctgcta ttgctattgg
     7321 tatttgagtc ataaagaaaa ttcctaaaaa tttaattgct gaagccatta ccccacctga
     7381 tgggtctggg aaagccagtg ctaattgtat tgaagttatt gtatatgtgg ctaagtctcc
     7441 tattgctgct gcaagaaata ctggaatagc attatttcca tcttttttct ttaaagcctt
     7501 aaatattagg aatgatacga ttggccctat tatcgccatt gaaaaagcat tagctcctaa
     7561 agtagttatt cctccatgtg ctaataacaa tgcttggaat attaaaacta tagttccaag
     7621 aacaaacatt acgcttggtc caaacattat tgctccaaga cctacaccag taggatgtga
     7681 acaacttcct gttactgaag gtatttttag tgctgataat acaaacacaa atgctccaca
     7741 taaagctaat aatactttct ttttagggtc ttgctttact attttaccta ttgattttaa
     7801 tccgaataag aaaaatggta taaatataac tccccatgct atagaccatt ttactggtaa
     7861 gtaaccttcc attatatgca ttgcatttga tgtaactgga gttaaaatga ttaacataag
     7921 tgcagctata acccctaatt taatattctg tttcatctta gtatccctct ctccctttct
     7981 aataattaaa acataataat acatgtctga tttatttaat aaaataaaaa agcctaactc
     8041 gatggttagg cttctaattt tccacaatct aaatacaaac acataaaaca aacatatctg
     8101 tataattatt ataagaaact ttctccatcc ccgaagaaat tactttaata ttttaggcag
     8161 gtctcctgac ttagcttcat cctactcctc ttccttccca tgagatataa aaaatatcat
     8221 catagtggct aacaaaagtt tcgtctgcat cacagtagcg ggggctgtaa aggaatttaa
     8281 cctttttccc tattaatctt gcttaaagaa cctataatat tatatattta atttttaaat
     8341 tattcttaaa tcattttcta tataaatcat tgtatacctt ttctgtgaaa atttctacat
     8401 tttttataaa ttttattcat ttttatattt ttatgtatat aaattctttt ttgtaagt
//
LOCUS       DAEOTL010000134         8199 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEOTL010000134 DAEOTL010000000
VERSION     DAEOTL010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.136"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            137..1030
                     /locus_tag="KRH82_003659"
     CDS             137..1030
                     /locus_tag="KRH82_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8656909.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIRIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            1208..2032
                     /locus_tag="KRH82_003660"
     CDS             1208..2032
                     /locus_tag="KRH82_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8656910.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            2131..2739
                     /locus_tag="KRH82_003661"
     CDS             2131..2739
                     /locus_tag="KRH82_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8656911.1"
                     /translation="MKKLLRGKIMKADSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            2843..3019
                     /locus_tag="KRH82_003662"
     CDS             2843..3019
                     /locus_tag="KRH82_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656912.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            4213..4965
                     /locus_tag="KRH82_003663"
     CDS             4213..4965
                     /locus_tag="KRH82_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656913.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            4955..7066
                     /locus_tag="KRH82_003664"
     CDS             4955..7066
                     /locus_tag="KRH82_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656914.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCTVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISVVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYRLPSVWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            7399..8109
                     /locus_tag="KRH82_003665"
     CDS             7399..8109
                     /locus_tag="KRH82_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBG8656915.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT         3103 a         1048 c         1095 g         2953 t
ORIGIN      
        1 aattaatcaa aatataaaaa ataggatatt attataggca ataactaaca tcaagcgata
       61 acttaataca tataaaaata aataaacaat taataaaaat taaaacttca ttataaaacg
      121 gaaggatagt gaaaaaatgc aactatataa cacccccttt aatacaaaca aacacttaat
      181 ctatttcttt acatttacgc tagtattgaa ctggatattc agtcttacac ctgcgttgct
      241 cggaattaca aatacaatac ttggagaaat cattttttat cttgcatata catcaccagc
      301 tattgtaggt ctatttttta tttctacaat ctatccacaa agtgcaaaac aagattttat
      361 ttatagatac ctaagcttta aagaaattag aataaaatgg atactattaa caatattatt
      421 ttttgcttta acttttatta cttcgttaat aatcggaaat tactttaatg taaaaacttc
      481 tgatatagat tggatacaca tagcagtgtt tagaccttct aaaatagctt atatgctatt
      541 agcaagtttt atattgagta tacttagtca agaagctgga tggagaggat atgccattga
      601 caaattatta gttagatttg gatttatagg ctcttcaatt attttagggc ttgtttgtgg
      661 aatctggtat ctagggtcgt attttacacc taatcaaata ccatataatt tggcacaata
      721 ctccctattt gatgcttttt tatttatacc aaacattgta cttttaaact ttataattaa
      781 ttttgtatat atcaatacaa gtagaagcat tttatcagct gggttagttc atatgatgta
      841 ctattttttc aacattcaat tacttctaca ctaccctatt aaattatgtg taatagctca
      901 atatgtacaa ataatatttg gtttaatatt tcttgtatat atgatttctt ctaataaatt
      961 taaacagaag gtaaattctg aaattgaaca gataaagtcg gatgattttg aatttgagtt
     1021 agactggtaa ttttaatatg aattataaat taagataatc tatgatttga tacgattact
     1081 acttaaatat aatttactct ctataattta ttgtaacatc tggaaaataa ttgtatttcc
     1141 acaaacgctt gaagtatata aaaacaaaat atatactgat tataagtgaa aaggaggtca
     1201 tattttcatg tttaaaatag gagaggtttc aaaactaaca caaatttcta ttcgtatgtt
     1261 gcgttattat gatgaacttg gtattttaaa acctgcaaaa acagacaaat atacaggtca
     1321 tagattatac tcagttgaac agatttcaat attacaaaga attgtattat tgagagattc
     1381 aaaatttagc gttgcagaaa tagcaaatat cgtacataat tggaatgatg aatttgtaat
     1441 taaggaattg aatagaaaaa agaatgaaat acaaaaggaa ataaagcagg aacaacaaag
     1501 aataaataaa attgataaat ttatagaagc tataaactgt gataaagatg aaattcatta
     1561 caatgttgtc tttaaaaaga ttccaagtta taaaatcata tcacttagag agataattcc
     1621 agactaccaa tctgaaggta tactctggga aaagctatct aaatttatca aagaagaaca
     1681 tatagaagta tcacgtcaat ccaacaataa catagctttt taccatgatg aagaagtcaa
     1741 agataatggt gtagatattg aagttggaat ggttgtaaag aagattggaa agaacaaatc
     1801 tggatttata tatcgtgaga cagaagaaat tgatatgatg gcatgtacta tggtttatgg
     1861 tccatatgaa aatatagctg gtgcatatga atcgttctgt tattggttag ataaaaatag
     1921 tgattatcaa atatcaggta taaatagaca aatcggtcat aaaggtgaac ataatgaaat
     1981 aaatcctgaa aattatctta cagaaattca aatccccctt ataaaagtct aatcgattag
     2041 tacttaaata cttaagtact aatcacccat tgacatccca aaattttcat gatagtatct
     2101 aaacgtgtat taaacatgtt taattttttt atgaagaaac ttttaagggg aaaaattatg
     2161 aaagcagatt caacaaagga acaattaatt aatgccacaa tccagttact atcttcacat
     2221 agagatgttt caagcattac ggctagagaa attgtagcta aagcaaatgt caatttagct
     2281 atgattaatt attattttaa atctaaagag gagttaatta atatttctat taaaaaattt
     2341 ttaaagcgtc atatggatga atataaggct acacatgata ctaaaaattt agcacctaaa
     2401 cagcaattaa gggaaatact aattgcattt tttgatttta taggtgaaca tagtcaattt
     2461 ataaagattt ctgtacccta tatattgata caggaagaaa ttgtttatcc atttgagata
     2521 ctacctttaa ttaaggctca ctatgaaaat cagaataaca aaaaaactga agctgaatac
     2581 agaactattg cgtatcaaat aacttcattt attcagttgc tttttcttcg ttctaatgct
     2641 tttttcaagt atagtggtat tgatattctt aatgttgaac agagaaatgg tttaatagat
     2701 tttcaattag atttattatt ggtagatatt acaaaataat actatattaa ttttttatgt
     2761 acattttttt attttatggt aacgtttgaa aatattctca ttgactaaaa atacttgcat
     2821 taaataaggg ggaggaattt taatgttttt tacatttata ggagtaatat cagcaatttt
     2881 attgttgtgt acaattatat gtggtttatg gataaaactt aataatcgta ataatgactc
     2941 taattctcac tttacttttt caatactttc aattgctttt tcactgttaa ttgtggtggc
     3001 ctttttagta agaaattaat gtctttgtta tgctgaggtt tattattata gatttttatt
     3061 attgcatgat ttttactata ttatagtatt tttattatat tacagggtct tatttattat
     3121 agtgttttgt tgttacagca ttttattata ttacagagtc ctatttatta taggattttt
     3181 attatattgt aaaatcttat ttattatagg attttgttat attacaatct cttatttatt
     3241 gcagtgtttt gttattacag tatttctatt atattgcaaa ctcttattta ttatggtatt
     3301 ttgttattgc aacatttcta ttatattgta aagtcttatt tattacagtt ctttattata
     3361 ctacagacct ttattattac agcatttcta ttacattgta aagtcttatt tattacagtt
     3421 ctttattata ctacagactt ttattattac aatctcttat ttattacagt tctttgctat
     3481 actacagacc tttattatta cagcatttct attacattgc aaagtcttat ttattacagt
     3541 tctttattat actacaaacc tttattatta caacatttta ttattttaac ttctttacta
     3601 taatatagta atattttaat atctcaaaat catatcaatc acttttcagc atagtctaaa
     3661 atacttccac tttctaaaat tatctatcat acctatacta ataatacttt ttaacctttt
     3721 tattataaat ttcaattgtt tttaacaacc tatttatttc caaaactcca atatattttc
     3781 tcaattacat tgtgttaata gcccctaaat cctttcaaat tatttacaat acattccatt
     3841 aaataatctt actgctctat aattcttttt ttctttttaa ccctactata cattatttac
     3901 atcatttttt tcaatacaac attcgttatt ctataacctt tttactttta ctatatactt
     3961 cttttctaac tacaccttca atgttccaca tcatattact ttagcacaac aattaatacc
     4021 taaaaataac cctctaaatc ctccaataat ataatcaatt taactataat aataacctct
     4081 cacactatcc aaacaatata ttttcaaaca ttacaaaaaa acatccaact attacaatat
     4141 agctcatatc cctcctcccc tttcaaatgc tatcattgac ttacaagata aatgaaagtg
     4201 aggatgatat atatgcttaa agtaaaccaa ttatgtaaat catataaaac aggcagtaaa
     4261 acatatcctg tattaaaaaa tatttctttt gaaatcaaca aaggagaatt tgtcgcaatc
     4321 atgggttcat caggaagtgg aaaaactact cttttaaatt gtatttcatg ttttatccca
     4381 attgataatg gggaaataat tcttggaaat aataatataa gaaatttaaa agaaaaggaa
     4441 ctttcagaag ttagaaatca acaactagga tttgtattcc aagacttcat gctatttgat
     4501 ggtcttagtg tctttgaaaa tatatgtgtt ccacaaatta tcaaaggtag tcaagtctta
     4561 caaatggaaa accgtgcaat taatctatgt gagctatttg gtattgaaca tatcagaaaa
     4621 aaataccctg ccgaaatatc tggtggagaa aaacagcgta cagcagtagc aagagcactc
     4681 atgaacaacc cagatttaat attagcagat gaaccaactg gtaaccttga tagtaagtct
     4741 tgtcgtacag tcattgaatc atttttaaaa gcaaagcaag aattagatgc tactatactc
     4801 atggttacac acgatagctt tgcagcaagc ttctgtgacc gagttattgt gcttaaagat
     4861 ggaataattt ataaagaagt tgtaaaatca aattcaagac ataaattcct agatgaatta
     4921 ctagaagttt taaaagaaat gggaggcgct caagatgaca attaataaat tatacagtaa
     4981 acttcgagcc tataattgga agaactatac aactttattc ttttgtataa tactttctgt
     5041 ggtattagta acttcatatg ctctaattta ttttagccca acaatacaaa acatacttcc
     5101 aactggtgga gatagcagaa aacaggctac aatgatattc tcagttgcta tattaggatg
     5161 cactgtcttt actacatacg catcttccct ctttttaaaa tttaaaagca aggaaattgg
     5221 tattttcatg gctctaggaa cagataagaa gaaattaaaa aaacttctat tttcagagat
     5281 attgttaatt tcagtagtat gctgtttttt aggtcttata ttaagtattc ctgtatcttt
     5341 tggtatatgg aaaatatttc aattagtgat tattgatacc agagaaatga catatcattt
     5401 tggaactcaa ggattcatat atggatttat atttagtgta tttgtgacat tatgcatatt
     5461 tatactttct gtaaaattta ttaatcgtac aaatataatt gatatattaa atgaccagag
     5521 aatatctgaa ccaatacagg atgtaaagga ctggtatggt atattaggta taatttttat
     5581 tatactaggt atttttctag gatatctcgt accttcacta actataaaca aattaaatta
     5641 tagactacca tctgtatgga gctttactta tctactctct cttattggaa tatatatgat
     5701 tatgacatac atagttgtac atgctaaaag aggaaaacat ccagagaaat actataaaaa
     5761 catcatatca actagcatga tgagatttat gggaagacaa acagtaaaaa acatgtgtgt
     5821 tatttcattt ttgattgcag gagcattatt tgctgtattc tatgttccta atatggttac
     5881 aggtatctat gatactctta aaaataaccc tatagattat acttttacct acaatcaaag
     5941 agataaacag gtatcaaaaa aagatattga acaattagca gataaacaca atataaaaat
     6001 tcaaaactat atggaaattc cttctataga attaattgtt gatggtgtag aatcaatata
     6061 tcataaagat ggaactatcg aaaaggtata tatgaaaaaa agctcctatg atatgttctt
     6121 taattctaaa gatttttcca agctaattgg caaaccaata actataaaaa atggtgaata
     6181 tcttgctgtt gtaaataaag gaaatgaaaa tcaagattat aaatatacca aatttatatc
     6241 aagcccagtc acagaaaaag aaatcccctt tagatatgct ggaaaaataa tatttaatgg
     6301 ttcttttttt caaaatagaa gtatgaacgc ctatgtcctt aatgatgagg attataaatc
     6361 atttactaaa gatttatcca taaaaaatta caataattct atactattta atgtagataa
     6421 agatacctat gcttttgcca atgacttaaa gaaagaaatt ataaaaagaa catctaagga
     6481 aatgggcatg ttcagtggtt atgatgaata cgtaaaaaaa cgttatgaat caactggaag
     6541 aaaatatttt atggatgaag aatatccaag tggtgaaggt catttaaaac tagacccaaa
     6601 caacaatcag ttgtatctta attggaaata ctatcctaac tttaaaattt tacaaagcca
     6661 agatatgata aaaaacatgg cagtcttctt aatgttattc atatatgtgg caatcatatg
     6721 ttttacagca gtaggaatca ttgcatatac aaggggtgtt actatagcta taaatcacaa
     6781 gcaggtcttt atggatttaa atcgattagg agcaaacaat gattatataa agttctgtat
     6841 tagaaatcaa ttaaagaaag tattttcata ccctcttatt gcaggaagtt ttttaattta
     6901 tctgtttaat tttatgatta tgttaaataa tgatggtaga atcgtcaata gtgaggtcaa
     6961 tgctcttttg ataaacttag gttttatagg gatttgtggg gtttatatgt accttatata
     7021 tctattaact tataagaaat tcaaaaaaat tattggtatt ttataataaa aaaggttatt
     7081 agatttttaa agtaataaaa tcattggtgt tttataataa gaaaggttat tagattttta
     7141 aagtaataaa atcattactt tttataataa taaaagcatt tgtattttat aataagaaag
     7201 attgttagat tttttaataa gaaaatcatt agcacttcag aataagttta atagaatagt
     7261 tttaagtgta agtatactaa tataaaaaat tttattttgc tatctggata taattgttat
     7321 ttcattttat atatctaggt agcaaaatat attatatact taactatata aatataaaat
     7381 ttgaaaggag ataaaaaatt gacttcgatt tgtatttgtg atgatgaaaa acaacaaaga
     7441 aacatgctga ataaaatcat tacaagagaa atggatttgt ggggctaccc ctaccaaata
     7501 aaagaatatt caaatggaga aagtctagta tacaatctag aacacgaaaa ttattacata
     7561 gatattattt ttttagatat tgaacttgga aaaagtaatg gcgttgacat agcaaaaact
     7621 atacgaaaac attcaaagga tactataatc atctttgtca caggtttttc tgactatgta
     7681 tttcatggat atgatgtagg agctttgaac tacatcttaa aaccttataa aactgaaaaa
     7741 atatgtaaag tattaaaaga agcactaaaa aaattagaac aatggaaaga aaactttatt
     7801 acagttcaga ttggaactaa tctttgtaaa attaatacaa aagatatcct ctactttaaa
     7861 agtgagctaa gaaaattaac tgtagttacc tttgataaaa cattagaata ctacggaaaa
     7921 ttaaatgata tggaaactgt tcttccctct aattttatac gtacgcatca aaggtatatt
     7981 gtcaatctaa accatgtaga tagtataact caaacttatg ccaaagttca gaatgaaaaa
     8041 attcctataa gccgtaaaaa atatcaagag gttgtaggaa aatttacaag gtatatgtta
     8101 gaatcttaat ttttgaagtt caatctctag aattttattt ttgaaactta attttttaaa
     8161 gcttagtttt tagagttttg ttttttcaaa tttaatttt
//
LOCUS       DAEOTL010000135         7950 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEOTL010000135 DAEOTL010000000
VERSION     DAEOTL010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.137"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(479..1297)
                     /locus_tag="KRH82_003666"
     CDS             complement(479..1297)
                     /locus_tag="KRH82_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBG8656916.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQVFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            1465..2046
                     /locus_tag="KRH82_003667"
     CDS             1465..2046
                     /locus_tag="KRH82_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8656917.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCIINGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            2043..2237
                     /locus_tag="KRH82_003668"
     CDS             2043..2237
                     /locus_tag="KRH82_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656918.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTILLIIYIKK"
     gene            complement(2401..4143)
                     /locus_tag="KRH82_003669"
     CDS             complement(2401..4143)
                     /locus_tag="KRH82_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBG8656919.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKIQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQNGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            4572..5948
                     /locus_tag="KRH82_003670"
     CDS             4572..5948
                     /locus_tag="KRH82_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBG8656920.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            6259..6930
                     /locus_tag="KRH82_003671"
     CDS             6259..6930
                     /locus_tag="KRH82_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBG8656921.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            7119..7916
                     /locus_tag="KRH82_003672"
     CDS             7119..7916
                     /locus_tag="KRH82_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBG8656922.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRVVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         2937 a          972 c         1221 g         2820 t
ORIGIN      
        1 aaattctagt catttaaaca taaaatcata attgatttat ctgacaaatt gagataatat
       61 cctaattaaa ttgtaggtat ttaaacataa cattataaat aatttatctg acaaattaag
      121 ataatatcct aatcaaattc tagtcattta aacacaacat cacaagtgat ttatctgtca
      181 aattaagata atatcctaat taaattgtag gtatttaaac ataacatcac aagtgattta
      241 tctgtcaaat taagataata tcctaattaa attctagtca ttcaaacata acatcacaag
      301 tgatttatct gacaaattaa gataatatcc taattaaatt gtagatattt atacataaca
      361 ctaaaagtaa tttgtttaac aaattaagat aatatcctaa tcaaattgta ggtatttata
      421 cataacacta aaagtaattt gtctaacaaa ttaaaatatt atccaattaa tataaaaatt
      481 acttcttttt aactgggaag catacctctg ttacccaatt atcaggatta ctatcgttgc
      541 caggacttac atgataaata ttaaacatag gaccatctac atcatagtta ttatctgata
      601 tccaattacc aatagcctca caagcgtctg caacttgatt gaaatttcca ttaacaattg
      661 cagttgcagc agtcacactt ggaacagtct taaatttaac atgttcagta tctttatact
      721 ttccagatac agcaacttgt acttcaacat ctacataatc ttctttatat ccagtatcat
      781 aaaaaactgc tttagaatac tttgggggtt caatttgaac attctggtct tttgtctcta
      841 aaaatacttg atgccataac attccttcgt cttgataagt tggtataacc cttctaagtg
      901 tcatcatata ttttggtgca aaattcttta tagttacatc ataatttttc ataatatcat
      961 ttcctccaat tcttttaata gtggtttcta tttttaatag ttttttctgt gtatcttcta
     1021 attgttcttt tacttgagaa tggtggatat ttagatattt tatgagactt tctttatcgt
     1081 tatattctgt caaaatttct tttatagaat acaagccaaa gcccatatct tttagtgcat
     1141 ggattctgtt tgtagtagaa agttggtctg cactatagta tctatatcca ttagttttat
     1201 tcgtatgaga aggagttaaa agtcctattt catcataatg acgtaacata cgaatactaa
     1261 ttttacttag ctttgaaaaa tcgcctatct taaacatgtt tttgtctcct ttataaaggt
     1321 acttttagct taatattaat ataaaccata tcataatgtt agagtcaact aaaattataa
     1381 ttaaattata ttgacatatg atgaaaaaaa tattatactg aacatgttca gaactgaaaa
     1441 tgttaattgt tttggaggtc tattatgaaa agtaatgata aagatgctag agaacgtata
     1501 attgaagtta cattgaatct tttaaatgaa gtagatgata ttgaggagat tacagttaga
     1561 aaaattgctg agcgtgcaaa tgttggagtt ggtttaataa attatcattt taaaacaaag
     1621 gataatttgt tgagtactgc cataggagat gtgatgtcaa atataatagc agagttatat
     1681 gacgatagtg tatatactct aagacctatt gaagatttga aaaatttatt aaaaaaattg
     1741 tgtgatactg gattacatta tgaaaaagtg cttccttttg tgttgaatca atgtataatc
     1801 aatggagata tgcaagcaga acttgatatt gtccctatgc ttcgtaaaat ttttggaaat
     1861 aaaaaagatg aaatgagtct aagaatcatt gccctgcaaa ttattttacc aatacagatt
     1921 tctgctttat ctacagaatc atttcagtta tacagtggta taaatataaa gaataaatat
     1981 gagcgagata aattcattga tattttaata gaaaatatta ttggagagga tgttgatgta
     2041 agatgaaaat tataactatt ggttcaagtc ttatcactgt tttacttttt ctttcaacta
     2101 tggtttgtgg gttctggatt aagaataata aggtaacaga tgcaagttct attaagttcc
     2161 atatgaatag tgctattttt acagggatat ttttattgat ttccacaatc cttttaatta
     2221 tatatataaa aaaataataa tattattaat aaataaagta tcagaaatta taaagacaag
     2281 agtcttaaaa atttctgata ctttaccata taattttatt aaacattaat tgtgtgtgaa
     2341 aaaatatcac ttatttcaat ctaatactaa atcttaagaa tgagtataaa gtattagaaa
     2401 ttaagaagca ttttttagtt caagtggatt atctatacca aaataatcat ataaagtaga
     2461 gcttatttcc tctaaatttc cattttggaa aggtaattgt aaatttacct tttctaccac
     2521 atctttaaat ccagcatcag tattttgatt taaaaaatcc atatatacat caacagcttt
     2581 tctgtaatct tcttgtgata attgccatat ctgaagtgat acatcagatg caagaccata
     2641 actcaagtaa taaaaaggaa cttggaagtt atgagataca agtatccaaa aaggagcatt
     2701 tttttctcta agtatattat tggaaactcc atattcttcc tctaaatcaa aaaacaattt
     2761 attgatatca tttagactca tatatggatt cttgtatata atttcttgaa attcatcata
     2821 aagacaagca tcaataatag tatttaaaac aatcgataag tgttcttttt ttatagcttc
     2881 agattgttta ccaaaaaaat catcaaaata tttataaaat agaatttcta aagatgttga
     2941 atgaacttca catacatcta tacttggttg tatcttatta tttaagttaa tactgttgta
     3001 gtaattataa aaatgaccaa actcatgagc aaaactagta acacctaaaa aagaattgtc
     3061 ccatgtatta aacaagaaag gtgctttata tttatttata taagtagtat atcctccagg
     3121 tgatttgttt tttccagaag aataatcgta caagtcatat tttttcatat agtcgaagct
     3181 ctcttttagt tttggagata tatcttcaag tactttatca aacttcctaa atgagcgatt
     3241 tttatatact ttaatataaa tagaagaatc agatggttta gatgaaatct ctctatataa
     3301 tggaactatg taatctttta cgtcttgtct aaatttttta gcttcttctt gagaatagtc
     3361 tttgtttagg ttcatatagg cataatctat ataattctta aatccttgct tacttgctat
     3421 ttcagttctt gtctgtataa gttctaagaa tatgttacca aatataggat tgtatttttt
     3481 taagtaatct gaataaattt tcacatattc ttcagggcta agatttggtc ttgacaaggc
     3541 ttcttcaaag tctacctcta taccatctat tgatactgta gatttagcta ataagtcttc
     3601 atattttaca actaggtctt gctctttttt aagcaaacct tcaacttctt tagaattaag
     3661 ttttccaatg ttctttagat aattaaatgt atcctttcca agttcttttt ctaattcttt
     3721 agagaattta gaagttacaa atctatcttg aaagtctttg tatgacatgt caacatctac
     3781 tgatttactc ataagatact tatattcctt agagtaaaat tcgtctgatg aatctatgtt
     3841 atttctaatt tttgctatag taagtgtact gtaaaaatct tgataaattt tatcaacttc
     3901 attaaataaa tttaattgtt ccttagctgt tttagctgtt aaaagtttgt cgttgcactt
     3961 gttaatgttt tcgcaaattg actgtatatt aggacgctta tattccattt tttcaaaagg
     4021 aatagttcct ctaacagaat ctttttttgt atcattagta taatttctta tgtatgatgc
     4081 aaatataata aaaactgcaa ttaaaattag aaaaacaaat attttcttct tggatttaac
     4141 cataaaaatc ctccaatcat ggatatagtt attaattatt ttactatatt aaatataaaa
     4201 aatgcatgtt aagaaaattt aacataaaga tatagataag attataaata atataaaaaa
     4261 tttaacttca aaaaagtata tgaaatttat actggtaaaa tgataaataa attttaagta
     4321 caaaatagta aaagctatga tagttttaga cctattatat gtaaaaaata tagatgtttt
     4381 tggtgcaatt taaattaaaa gatatatata aaaatttaaa atattccaaa cagaaattat
     4441 aaaaattact atcattgtct ttatacaata tttatactat aatagaataa taatttagag
     4501 gaaagctcta aaaataaaca aattaagggt cttaacagta gtgattttat gttaaggagg
     4561 tataaagaaa gttgaaaaca atagttagaa gacttattct ctacgcagat ggaatgcgtc
     4621 ctactcaaat aatggtatct gggtttgctg cgattattgt aatcggagca ttgttgttaa
     4681 cactcccgat agcgtcgcag agtggagaga gtataggctt attaaatgct ctatttacgg
     4741 ctacttcagc ggtttgtgtt actggtctag ttatggtaga tacagcaact tattggagtt
     4801 tatttggaca gatagttata ataacattga tacaaattgg tggtcttgga tttatgaccg
     4861 tagccacaat gttttcactt atggcacgaa aaaaaataca actaagagaa agattattaa
     4921 tacaagagtc attaaatcaa gctgatttat cgggacttgt aagacttaca agatttgtat
     4981 taataataac cataacaata gagggaatag gtgcactggt tttatcaact gtctttattc
     5041 cacaatttgg tttgtctaaa gggatatggt atagtgtatt tcacgcaata tcagcgtttt
     5101 gtaatgccgg atttgacttg atgggcagtg taagtggccc atttacatcg ttaaattctt
     5161 atgtaaacaa ctttacagta tcaatgactg tttgcgcact tatagtgctt ggagggctag
     5221 gattccctgt tgtacttgat attgtaagaa aaagaagatt ttcaaaatta aatgtgcatt
     5281 ctaaggttgt attgttttca actgctacac ttatttttgt gggtgcatta tttatttttc
     5341 ttatagaatt taatcaaaaa gctactatgg cggacttgcc tttaaaggga aaagtactat
     5401 cagcaatatt tcaatcagta acagcaagaa ctgctggttt taatacgctt gatttagcta
     5461 ctttacgaga aagtagtgta tttgtaatga taattttgat gtttattgga gcatcacctg
     5521 catcaactgg tgggggtata aaaacaacaa cactagctgt tttaatcatt acagttagaa
     5581 gttttctatc aggaaaatca gatatagaag cttttgaaag aagattagct ccatcaacta
     5641 taaaaaaatc tcttggtata tttgtaatca gtatatcagc agttattttt ggaacattga
     5701 ttatttcaat aactcagcct aattttacat tagttcaatc agcttttgag gttacatcag
     5761 cacttgctac agttggttca agtttagctg gaactccaaa cttaaatgct ttaggtaaga
     5821 ttataataat aatctttatg tttatgggta gagttggttc tcttacttta tttatggcta
     5881 tactttctgg tggtagaaga aagagtcaac caatcagata tgcagaaggt aaaattatgg
     5941 ttggttaagt taccaagaag tagtataaat ttataatgga tttagagtag cactgtaaat
     6001 ctgttgataa aataaatgag cctagatgta attatatgaa gaaataaaat cgactaatga
     6061 acaaaattaa ttaatgaaat aaaaaaacag ggaaataaaa tacaaataaa aaggtaaatc
     6121 aaaattaaat taatctgtgt atataaaatt atatattgtg tataagtttt gtatgtgtaa
     6181 agtatataag ttttgtatgt gtaaacaatt aatttaagag atattatata aattgtgtat
     6241 tagggaggaa gtttcgagat gaagcaatat atagtcattg ggtgtgggag atttggaagt
     6301 tcagttgcgt ctactatgca tcttttagga catcaagtaa tggcaataga caaaaatgaa
     6361 gattcagttc aaagtatatc tgacaaggta acccattcac ttatagtgga tgttactgat
     6421 gagcaagcgt taaggtcatt aggtttaggt aactttgatg tagcagtagt tgcaataggt
     6481 tctgatataa gggcatctat aatggcgact cttatagcca aagaaatggg tgtagagttg
     6541 ataatatgta aggcaaagga tgaattacaa gctaaagttc tttataaaat tggtgcagat
     6601 agagttgtat ttccagaaag agatatggga gtaagagttg cacacaattt agtttcggat
     6661 aatatattag accatattga acttgaccca gagtattcaa ttgttgaaat cgtaactcca
     6721 aatagttggg ttggcaagac acttatagag cttgaattaa gagctagata tgagataact
     6781 gtacttgcta taaaaacagg taaaaatata aatgttacac cttctccaga tgaggaactt
     6841 acagccggaa gtatcctagt tataatcggt caaaatacta gtataacagc gataacatct
     6901 ggaaataagg ggataattag aagaagataa tttactattt aatatatatt taattgcaat
     6961 gaaagtagat agtatcatat aattatgaat agttatatga tactattttt ttaatcgaag
     7021 gtagtattta tttgtaagat tagataaaga gaaattaaat taaaagtaag gaggctgtgc
     7081 taatataaaa atttataagt tattagcatt tagataaaat gattacaaat ataaacagta
     7141 aggataatga aaagttaaag tatacaagag cactattaaa atcaaagaat aggaataaag
     7201 agtcaaagtt cataatagaa ggatacagag tagtaatgct tgcacttgaa tgtatggcaa
     7261 accttgatta tgtatttatc aatgaagaat ttgaaaataa gaaagaacat gtaaaactat
     7321 tagaagattt ggataaaaaa aacacaaaga tatacaagac tactaataaa aactttaaag
     7381 aattagtgga tacagaaaat actcaaggaa taataggtgt agtttcattt aagaaaaaaa
     7441 aattaagtga aagtataaat aaaaaagata aatttgtatt gattttagac agaatacaag
     7501 acccaggaaa tatggggact ataataagga ctgctgattc tgctggagta gatgccataa
     7561 tagcactaaa gggatgtgtc gatatataca acccaaaagt aattaggtct actatgggtt
     7621 ctatttttga tatgaatata attgatgctt cacaagatga aactgtggac atgcttaaat
     7681 cattggattt taatatagtt tcaagttact taaatacaga aaatttttat gacaaaatag
     7741 attatggctc aaaagtagca ttggtgatag gaaacgaagc aaatggaata aatgaagaac
     7801 ttgtatcaaa gtctgatatt ttggttaaga tacctatata tggtaaagcc gagtcgttaa
     7861 atgctgcgat aagctctgct atactgatgt atgaaataaa aaaatactta atttaatgta
     7921 ttgtaataaa tataatgtca tgttataatc
//
LOCUS       DAEOTL010000136         7335 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEOTL010000136 DAEOTL010000000
VERSION     DAEOTL010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7335
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.138"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(22..684)
                     /locus_tag="KRH82_003673"
                     /pseudo
     CDS             complement(22..684)
                     /locus_tag="KRH82_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(844..1380)
                     /locus_tag="KRH82_003674"
     CDS             complement(844..1380)
                     /locus_tag="KRH82_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBG8656923.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1453..1866)
                     /locus_tag="KRH82_003675"
     CDS             complement(1453..1866)
                     /locus_tag="KRH82_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBG8656924.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIIFIHDRECSECQEKVK"
     gene            2359..2997
                     /locus_tag="KRH82_003676"
     CDS             2359..2997
                     /locus_tag="KRH82_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBG8656925.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISGMNGTISDMQGSISS
                     MDGTINSMQDSITDMQVEIKEVNSRLDNMEPDIKDLKTGQVETSSRLDTIQSDVTEIK
                     SDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3605..3784)
                     /locus_tag="KRH82_003677"
     CDS             complement(3605..3784)
                     /locus_tag="KRH82_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8656926.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4010..4543)
                     /locus_tag="KRH82_003678"
     CDS             complement(4010..4543)
                     /locus_tag="KRH82_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBG8656927.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQITVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIVPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            4860..5210
                     /locus_tag="KRH82_003679"
     CDS             4860..5210
                     /locus_tag="KRH82_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656928.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVNRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYMYEALVSVSFLWLIMIKNIVLPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            5179..5498
                     /locus_tag="KRH82_003680"
                     /pseudo
     CDS             5179..5498
                     /locus_tag="KRH82_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(6046..6618)
                     /locus_tag="KRH82_003681"
     CDS             complement(6046..6618)
                     /locus_tag="KRH82_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBG8656929.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(6680..6943)
                     /locus_tag="KRH82_003682"
     CDS             complement(6680..6943)
                     /locus_tag="KRH82_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBG8656930.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(6943..7164)
                     /locus_tag="KRH82_003683"
     CDS             complement(6943..7164)
                     /locus_tag="KRH82_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBG8656931.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         2586 a         1243 c          881 g         2625 t
ORIGIN      
        1 agtgtgcgta gctatttttt aatcaaactg gaatacagac tccattccta ggaaattggc
       61 tgaaatatag tctgctgtca aagatgctgt catcacagaa attaaaacag atactgaaaa
      121 gtttttatgg acttcttcaa gtgaaaacat aacacccgcc agtggtgcat gaaaggctgc
      181 tgataatcca gcacttgccc cacaggttaa caggaatttt tcctctgtct tccctcggtc
      241 aagagctcta gaaatacctt tacctgccat agcaccaagc tgaatggaag gaccttccct
      301 tcccaaagca agaccaccca tgagtgataa gaatcctcca ataaattttg ttggcaacac
      361 tcgccaccat acttgtttta ttttccctgt catttccccc tcaagctgag ggataccact
      421 tccagaaatc attggctccc agtccaccaa ctttgataca atccatgcaa gtactgcaag
      481 tactgcaaac caagctatta tttttattgt agaaccttct acaaatttta aaatttggct
      541 aagccaagta ccagcctgcc ctaaaagtat cctgtataaa agcacaatca aaccagccac
      601 agccccaacc ataagtcctt caccaatcaa aattacctga aagtgctctg cccgtttgat
      661 aatatgagat gtatcctttt tcatactatt cctccttcat ccaataattc tacacaatct
      721 gaatctccaa tgactaaagt catgagtgtg tacagatatt ttttaatcaa caaaaataga
      781 tttttactta ctaaatataa gaaaataatt gctcaatttc tcaataaatg tgaatttatt
      841 cttttaggta tttattctcc acagtcgtgc ttcttccagc aaaatattta ttaattcttg
      901 ctttctctgt gtatagattt tacgattgtc ctcaaactgt aatgctaatt tttgtttatg
      961 actatcatag agttttgctt tgtctgtaaa agtatttaga taatctcgaa aattgatata
     1021 attattccat gcaacactat tccattcaac aacatgaata tggtgagtac gagtattttt
     1081 ctcaaaatct cccatagcaa aaagtaattg ttttggtaca tcctgacctc gaaaaacgat
     1141 tccacattgc tctaaccttt cgaggtataa tttagcttcc tctaaagaag caacacctac
     1201 aacaatatca ataataggct ttgcgctaat actgggaata gaagtgcttc caatgtgttg
     1261 aatatcaata gcagtcttat cccatatact tttcaataat ataatgacat cttttgcact
     1321 tttatcccat atcatctgat gttccaataa tttaaccata ccacatttta aacctatcac
     1381 tatataccac ctcaatataa tccaccttta tatatattac aattttttct atcttgataa
     1441 acagtgattt agctatttca ctttttcttg acactcgcta cattctctat catgaataaa
     1501 tataattcct ccacatttag aacaagtata tctctccttc tgcttttgca taaacttctc
     1561 taaaccgtac tgctgaacaa atttactatt ttccataagg cttgcttgat atctcttgtt
     1621 ataacttttt tcaagatttt ttatgagttt acaaggaaaa ttgaaacatt caaaacaata
     1681 aaacaaccct ttttgacaga cacaatcctt tattttacac ttacggcagt gttctggctt
     1741 tcctgtatcg ccattcaaac aaccagcaca tggctttttg tgataacaat gcttatagca
     1801 aaccatacaa ttcattccac aaggagcaaa cataatcgta tcaatactct cttttggcat
     1861 tttcataaca ttttactcct ttcaaaaatc caatttgtcg aattgttata tattcatatt
     1921 gtaacataaa aaatagctaa aaaattcatg cactttcatt gccaataaat tttcaaggaa
     1981 atatgaaagt ttaaaactaa gaataaaaag agataaaaag gaagctacta atcaaaatat
     2041 tcaaatacaa gtaatcaata taaataactt aaggtatatt taaaagtata tgatattacc
     2101 agcagtttta aatacaaata taaccacaca tgcctcaaaa acacttatta cagtatctta
     2161 gaaacttaga caatacataa gattcattaa taaaaaagtt ctcaatatag tcattaataa
     2221 aaacgttctc aatatagata tatttaacca tgttttgaat agcagataat tatatgatta
     2281 aaaattaaat atgacatagc gtttgtggaa tataacacct aaattatgtt ataataataa
     2341 aacaggagtg tgatagtgat ggatgaaaaa atattagagt tattacagga aatgcaaggt
     2401 aatattagta atatgcaagg tagtatcagt ggtatcgaag gcactattag cgatatgcaa
     2461 agcaatatca atggtatcga aggcactatt agcgatatgc aaagcaatat caatggtatc
     2521 gaaggcacta ttagtagtat gcaaggcaat atcaatggta tcgaaaacac tattagtggt
     2581 atgcaaggca ctattggcga tatgcaaggt agtatcagtg gtatgaatgg cactattagc
     2641 gatatgcaag gcagtatcag tagtatggat ggcactatta atagtatgca agacagtatt
     2701 actgatatgc aagttgaaat taaagaagtc aatagtaggt tagacaatat ggaacctgat
     2761 attaaagact taaaaactgg acaagttgaa actagtagta gacttgatac tattcagagt
     2821 gatgttacag aaattaagtc agatgtaaaa attaacagaa atacattaga tacagtgatt
     2881 aaacatacct cttcattagt aaaagataca tcagatatta aaaatgattt aaataatata
     2941 gagatagtca catctaagaa ttcgaatgat attgctaaat taaaatcagt taaataatat
     3001 actatagtaa aaaatacctg aaaatttcac atacttcttt aaagttatac caaattttat
     3061 acagaaatac tgattatccg acaacacact ttacttataa ataatttatt aaaaaaatac
     3121 tcattttatc ctaaaattaa cacgactaaa tgagtcttga tataataata aaaaataagg
     3181 gagattggac actaaaaagt tgtgtatctc ccttatatcc tataatatag ttatataatt
     3241 tttcagccta aaataaaagt ccatctttga ttaaaacaca tccccttatc acttataaaa
     3301 ggataaaatc ttgttttcat ttttccattt atatcttctt gcttaagagt aataattttt
     3361 tcttttgata ctttaagtgt ttggttaaat ttaaccaatc gactaagttt tgttcaacat
     3421 ctatttttca tattttccaa tacttaatct attttttata aataattctt tcatttctaa
     3481 ctcacttaca ttttttacat aaaacgaagc atataaattt caaccttatc ttgtatggtt
     3541 cttaatactt aatgagtagc ttaagtatca aacattataa attttcccct tacatttaac
     3601 actcttacca tttccaaaat atacaaaata tattttgaac atttgtacaa tgatgaaata
     3661 caatacatga aaatacaata tcataactgt tgtctaaaaa tagaagttct tcaacataac
     3721 ctttcacaaa aaacatatta tctaaatatt ttttgtctgc tccttgtttt cctgtttgta
     3781 gcatataaat tactgcatct aaacatataa ctactcacac gaaaaatgaa aataaacttc
     3841 caaaatacaa gctctaaaaa ctacctctaa agttgtataa tgtttactag gaataaggtt
     3901 gtataacata tagtttaaat aatcattttt taaaattgca agttattgct ttcaaaatta
     3961 gatgtttgta tatcaaataa atgattaaga atttctaaat ttaatggctt tataatgcac
     4021 tccctttctt tgggataaaa taatgttgca cagatacttt ttctaaagat aacaatttta
     4081 tttttctatc aattccacca gcatacccag tcaaactccc atttgttcct acaacacgat
     4141 gacatggaac aataatagag attccattat gccctactgc accaccgatt gcttgtgctg
     4201 acattttaga tattcctttt tgttgagcaa ctttatatgc aatttctcca taagtgattg
     4261 ttttaccata tggtatttgt tgtaaaattt tccacactgt aatctgaaaa ggagtaccta
     4321 ccatatggag tgatggtgta aaattgggtt cttttcccga aaaataaata tctaaccatt
     4381 tctttgtctg ctcgaaaatt ggcaattctt tttcttgatg ttcttggtca agattataag
     4441 cataatactt ttgattctca aaccaaagac cagttaaccc aatattatct gatgctaaaa
     4501 gaatatttcc aattggacta tggtaatagc taatatattg catacaattc ctccttatat
     4561 tctgaaaact tcactcaaat cattagacac ttcttttcta tctaccatta tgtaaaaaca
     4621 tactaatata atttccttct aactacactt tcgttataat atctatcctc atatcatatt
     4681 agttttatat ttacctgcat ctgttcatcc ttttttccct ttccttttga tgaatataaa
     4741 attcatacat ttaagcttcc tactgtatta acttttatag aagtgtatat tataatttta
     4801 tcactaaata gaccaaaaaa atatcgatat aacatcaagt aatatcataa tactttcaaa
     4861 tgggaaaagt aagaataggc tgtaaaaaag aaaagtattt ttatgttaga aatccagtaa
     4921 aatcgttagt aaatagaata acagaaaacg aacaattcgc tatttatcat tttacacata
     4981 aatataattg gcgcaataaa gtgttttcta ttctacaacg attaataagg ttagaaaaaa
     5041 gtaaaaatga actgtatatg tatgaagcat tagtttctgt ttctttcctt tggcttatta
     5101 tgataaaaaa tattgttttg ccaccaataa aacacaaaaa tataattaat atccatatgc
     5161 aaaaaatttt acgttatatt gaaaaatact attgttttac attatattga agggtactat
     5221 tgtgaaaact taattttgga gtactatcaa gcagtgataa tatcaataaa tcagagtgtt
     5281 ccagaggatt tgaactaagt ttaaatacta taccttgtaa atattttact gagttttgtt
     5341 tactaaaagc aactcaattt ctaaaaggca caaatgagct aataagtgac attgctataa
     5401 aagttgtttt tcatcaaata atctatttta gtaaatgttt taaagaaaaa acgggatatt
     5461 ctccaaaagt gtacagaaat ataaaaaaag agatatgatt ttttatttct tttgattatc
     5521 caaagagtaa ataaaaaata ttgtaaaaaa cttactaaca acggcaatgc tttgaactat
     5581 ggtaatactt tgaacttttg attggacttt ttttgctaaa ataatatatt taaatagcaa
     5641 agtaatctgt ttaatcaata aaaaataaga gataaaagaa atcaactaaa acttttacct
     5701 cttattttga tagtttatta gagctaatat ttacactctt tttatttttg atacttcatt
     5761 aaaaatgatg cttattctct tttcattttt aatacttcat tagaacttat gcttattctc
     5821 ttttcacttt taattcttca ttagaactta ttcttactct ccattcactt ttaattcttc
     5881 attagaactt attcttactc tccattcact tttaattctt cattaaaaat gatgcttatt
     5941 ctccattcac ttttgatact tcattaaaaa tgatgcttat tctctgttca cttttaattc
     6001 tttattaaaa ctgatgctta ctctccattc acttttaatt attcattaaa actgatgctt
     6061 gcactctgta aactcataaa catccattaa tgcttcacca aatctttgat agtgaactac
     6121 ttccctctca cccaaaaatc tcaatatatc tttcaaatca gggtcatcag ttaaatttat
     6181 taattgatag tacgtagcca atgctttttg ttcagcagcc atatcctcat gtaaatcagt
     6241 taccgaatcg ccaaagacat taatataact tgtagtaaag tttactccat tagaatctac
     6301 tggctgaaga ccatgtccaa aattagcata attactacca agtccagcag ccttaagctc
     6361 ttctggagta caattgccta ttaattgata taacactgaa gaaattatct caacatgagc
     6421 catttcctct gtacctatat cagttaaaag tgcacgagat tttccagttg gcatagtata
     6481 tctttgttga agatatctag ttgcagctgc caactcacca ttaggtcctc ccaactgagt
     6541 catgatatat tttgccattc tagggtctgc ttgtcttatg ttaactggat gttccagtgt
     6601 tttttgataa atccacatat tatcttactc ctccttaata tatatttaat aataaatcta
     6661 attttaaagt ttaataattt tatttataaa atgatttgtc ccatggccaa ggttcagata
     6721 tccatgacca aggatattca cttgattcat atccaaaatt agttaatgct ccatatttag
     6781 attcataatc acacacagct tgtgtaaatt tatcgcagta tctgttgtat gaatcaagag
     6841 ctttcttatc ccttggattg ttatctaaat ataaatttaa ttctatacag gcaaattgat
     6901 attctgaaat tctctctaaa agttctcttc tatttaatga cattagtaca tgttaccccc
     6961 ttttttagct ctaactctat ttttaggatt tgcatatagc caatcattat agttatttga
     7021 ctctattaaa tctaattcag gaaataaagt acctcttttt aatgctgttt ttggattgta
     7081 tgtgtcatca taaatttgac gattgatgta tggtctagca aattcacaac aatagtcttg
     7141 tttatcctct tttaaatatc ccattaatta tcctccttaa tttttagaat tttaaaatag
     7201 cattattttt aaaaattgta tactggttct atattataac tggtagtttt aataggtctt
     7261 taataagatt aaatgattaa ataagtatct ttttttctta ttttacctct aaaatttttc
     7321 taattaatct ttcat
//
LOCUS       DAEOTL010000137         7237 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEOTL010000137 DAEOTL010000000
VERSION     DAEOTL010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7237
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.139"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            467..976
                     /locus_tag="KRH82_003684"
     CDS             467..976
                     /locus_tag="KRH82_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBG8656932.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1004..1198
                     /gene="rpmI"
                     /locus_tag="KRH82_003685"
     CDS             1004..1198
                     /gene="rpmI"
                     /locus_tag="KRH82_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBG8656933.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1254..1610
                     /gene="rplT"
                     /locus_tag="KRH82_003686"
     CDS             1254..1610
                     /gene="rplT"
                     /locus_tag="KRH82_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBG8656934.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1920..2465
                     /locus_tag="KRH82_003687"
     CDS             1920..2465
                     /locus_tag="KRH82_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656935.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            2452..2625
                     /locus_tag="KRH82_003688"
     CDS             2452..2625
                     /locus_tag="KRH82_003688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656936.1"
                     /translation="MKGNKSDLHGVEPIYTENRFMIYICIQSKVSLLGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            2900..4825
                     /locus_tag="KRH82_003689"
     CDS             2900..4825
                     /locus_tag="KRH82_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8656937.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYINEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFISNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDELTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5226..7130
                     /locus_tag="KRH82_003690"
     CDS             5226..7130
                     /locus_tag="KRH82_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBG8656938.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVNVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3046 a          720 c         1361 g         2110 t
ORIGIN      
        1 tagtatatta gagtacaata tagaatttgt tatgtagtat agtagtatat tagaatacaa
       61 tatagaattt gttgggtagt atagtgttat attagaatac aatataggat ttgttatgta
      121 gaatatatag agtcatgtag aatatacata tataaaagga ttttgggtat aaatttaaaa
      181 attaatagca aaatgagtag tatagacata taatgagtag taggaagtaa ttaaattttt
      241 cctaaacaaa aaaaatagtt gcaaataatt tgattaagtg atatagtaaa taaggtaaga
      301 ataaaacaaa gaagaagtcc gcttctcacc ttacgccgga ggttagtaag gtaaatataa
      361 gttaaagctt aattttaatt taagtttgtt taaatttggt aacttatatt gcggatgatt
      421 acgtcatccg ctttttattt tataaaaatt ttggaggtgt cctacaatta gcaaagaatt
      481 agcaatcaat gaacaaataa aagataagga aataagagtc ctttcaccaa caggtgaaca
      541 acttggagta atgcctacta aagaagctca agcaatggct aatagcaaaa acttagattt
      601 ggttcaaatc tcgccgaatg caaatccacc agtatgtaag ataatggatt atggaaagtt
      661 tagatatgag caagcgagaa aagagaaaga agctaagaaa aaacaaaaaa ctatagttgt
      721 aaaagaagta agacttagac caggtattga acaaaatgat ttaaatacga aagctaataa
      781 tgctataaag ttccttaaaa aaggggataa agtcaaagtt gaacttagat ttagaggaag
      841 agaattagga cataaagaca taggtaaaga agttatgctt aagtttttag atataataaa
      901 agagtttgga gaaccaacaa aagcccctgc atttgagggt aataatatgg ttgtaattat
      961 agatccaaaa aaatagatga ttaactgaga ggaggaattt gtcatgccta aaatgaaaac
     1021 tcatagaggt gcagcaaaga gattaaagaa aacaggaact ggaaagttaa agagagctaa
     1081 agcttttaaa aaacatatat taactaaaaa atctgcaaaa actaaaatga acttaagaaa
     1141 atcaacttta gtaagtgatg gagatgctaa gagaatagca caattattac catactaaga
     1201 tacagattgt aaataataac tatagaagag ggatataaaa ggaggtcata acgatggcaa
     1261 gagttaaaaa agctatgaac gctcgtaaaa agcataagaa aatattaaaa cttgcaaaag
     1321 gattcagagg atctagaagc aaattatata gaccagcaaa tacattcgta atgaaagcat
     1381 taaaaaatgc ttatatagga agaaagttaa agaagagaga cttcagaaaa ctttggatac
     1441 aaagaataaa tgcagctgct agaatgaatg gaatatctta ttcaagatta atgaatggat
     1501 taaaattatc tggtgttgaa gttaacagaa aaatgttatc tgaaatggct atacaagacc
     1561 cagaaggatt tgcaaaatta gcagaagttg ctaaagcaaa attagcttag tattgaatca
     1621 tgagatgtaa agtctttgag ttatgtaaat aattcaagga cttttttatt ttttgaaaaa
     1681 tacttattag tgtcatgtac aaccaatttt ataatgataa ataaaataag caatacaata
     1741 gaattttatg agatttatta taagaattgt tacaattatt tatgatagct ataaaaagtc
     1801 atagtaaaaa tgatattgat gtatgttgat atatgtataa agctttcaat caatcttgaa
     1861 ttaatattat caacatgata atattatctt attaataata taaataaggg ggagataata
     1921 tgaatgaaaa actaatggat tgttttgtaa acccaattaa atgcaagtta ttgattgaaa
     1981 ttttttcaaa taatcgaact acagctaaac aattaggaga aaagtttcaa gatatatcaa
     2041 aggcaacact ttatcgttac cttaataaaa tgttgaaaga tgatattata aaagtggttg
     2101 aagaaaataa aataagggga actgttgaaa aagtatatgc tatgaagtta gatatagctg
     2161 atgatgtgaa caaaattata gatgagaact ctggagaaga atatgctcaa ctgtttactc
     2221 aatatatgat gggattttta agagaatttt atgaatacgc tgaaagaaag gaaaaggata
     2281 tcctaaaaga tggttcagga ttttctgtct gtccagtata tgctagtatt gatgagatag
     2341 ttgaagtgag taaaaaaatt gctagtatac tagaacctct aagaaataac tcacatgaag
     2401 aaggtagaag aatgcattct ataggagtga taattactcc acctaaagag gatgaaggga
     2461 aataaatctg atttacatgg ggtagagcca atttatacag agaatcgttt tatgatttac
     2521 atatgtatcc agagcaaagt atctctgctt ggattgtact tcattgtacc atttcatcca
     2581 atgacttgga gtggtacaat gaagtttttt aatttttcat attaatgcta aagaaatgaa
     2641 ctttagacca catatgcaat taggttgcat tatacaatta gaccacatat acaaaataaa
     2701 aatcagtatt tttatagcag ataaattgac tgttattctt cttaaaaatc atctattagt
     2761 tattgttagc atattgaaag aaattatagt aatctattga ataaatgaat attgcccata
     2821 atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata gtaatctaaa
     2881 aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg tgatattttt
     2941 aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag caaaagatac
     3001 agaaattaaa atattaggga caggtgattt acattcaatt ttgacagact ctatggtttc
     3061 atatataaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg cgggagattt
     3121 ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt taattaatat
     3181 taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag atgaagtacc
     3241 tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag ataatgaatt
     3301 tatttcaaat gataagcaaa gtcttgataa actggtttct gattttaaaa ataataatat
     3361 gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac aaccatatgt
     3421 aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag gtcttactat
     3481 aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa aagctagaga
     3541 gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag tagaagatgc
     3601 aaagaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg cagttgtaca
     3661 ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag agttagcaac
     3721 tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa tagatgaaca
     3781 caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt ggcatggaga
     3841 tagagtatca gagattaatt tcaaattaaa taaagagaat ggaaagtggg acataaagga
     3901 aaagtctagt aaattaaaaa taattgataa agaagtaagt atagttgcta ctgcagattt
     3961 acattcacat ttctctgatg aattaacagt tgaccttgtt aatgaacgta gtaacccaat
     4021 tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg aaatgactca
     4081 atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga ttagtagatg
     4141 cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg gaaatcatga
     4201 atttgtatct gaaaaagatg aattttggtc agatgaacgc cttttagatg ctgttataga
     4261 ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc aatctggtaa
     4321 aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta atgtaaaagt
     4381 aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg taaacttaca
     4441 agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag atgcaaagaa
     4501 atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg tacattcagg
     4561 agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag caactacagt
     4621 agatggtatt gatgcaattg ttgctagtca tactcatgaa aaaatagatg agcatgaata
     4681 taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg gtaaatatta
     4741 ttctaaaatt acctttaaag taaataaaga aaagggttcg tggactatta atgataaatt
     4801 cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta aattatctga
     4861 tattgacatg atatataaga taaagtttct aatattggta taatgcataa tgtgaaatat
     4921 tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa gatatagtat
     4981 gaactattat actaatgctt actttataat ttgaacatgt tagaataagt cttatttgaa
     5041 aattttagtg tattagagta agtattattt tactagtaaa aaatattgag aactatatgt
     5101 agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata gtacaatctt
     5161 atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct aaggaggagt
     5221 ctcttatgaa aataaaattt attatagtag catcaataat atttttaata gtattacttg
     5281 tggggtgtca aagcactaaa gatacagaaa tcaatgtact cgccacaagt gatttacatt
     5341 caattattcc agataattta atttcctatg tagaagagga gagaaaatat gatgagaatc
     5401 tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg aataagtggt
     5461 ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa aaaatagctg
     5521 aaccacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag tatgatgcag
     5581 ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat aaattggttt
     5641 ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa caatctggag
     5701 aaaactacgt aaagccatat gtaatgaaaa atataaatac tgacaaggga actgtaaagg
     5761 ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt aaaagttttg
     5821 aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg aaattatatg
     5881 caaatgattt agtagaagat gcaaataagt gggtaaatgt tatggaaaaa aaagaaaagc
     5941 cagatataat agttgccatt gtacattcag gtgaagagcc aaaaaatcct aaaaatccag
     6001 gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt gtagcaggtc
     6061 atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa gaagtaatag
     6121 taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag ttggataaga
     6181 agaatgataa gtggtttata aaagacaaat atagtgaatt aaaggttttt ggaaaggaag
     6241 taaatataat tacaacttct ggtctgaatc caaaattttc agatgaaatg gcagttaatt
     6301 tgtttaatga aagagataga gatgttcaac ctatctttat agatactgga gattttttaa
     6361 atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat gaaaataaag
     6421 gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat gctgtagtac
     6481 ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa tctacattgg
     6541 attatattat agaaaacttt gaagaaatga agataccagt attatcagct aatatatatg
     6601 atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa actagggaag
     6661 gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgaa gaagacttaa
     6721 gtaactcaag cttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa acaggaaagt
     6781 tatatactaa taatctagta aaagatgcaa gcgaatgggt aaaagttatg caaaaggaaa
     6841 gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta aaaaatccaa
     6901 gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt gttgtaggtc
     6961 atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat gaggttatag
     7021 taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga aaagaaaatg
     7081 gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga atttattgat
     7141 atataaacca ttattaacac tgatttttat aatataataa atactgattc tacaatataa
     7201 ttaacactga tttttataat ataataaata ctgattc
//
LOCUS       DAEOTL010000138         7206 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEOTL010000138 DAEOTL010000000
VERSION     DAEOTL010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7206
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.140"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            136..348
                     /locus_tag="KRH82_003691"
     CDS             136..348
                     /locus_tag="KRH82_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBG8656939.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            361..582
                     /locus_tag="KRH82_003692"
     CDS             361..582
                     /locus_tag="KRH82_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBG8656940.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            682..2838
                     /gene="feoB"
                     /locus_tag="KRH82_003693"
     CDS             682..2838
                     /gene="feoB"
                     /locus_tag="KRH82_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBG8656941.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            2864..3016
                     /locus_tag="KRH82_003694"
     CDS             2864..3016
                     /locus_tag="KRH82_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBG8656942.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            3196..3906
                     /locus_tag="KRH82_003695"
     CDS             3196..3906
                     /locus_tag="KRH82_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBG8656943.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            3991..4761
                     /locus_tag="KRH82_003696"
     CDS             3991..4761
                     /locus_tag="KRH82_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656944.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            4754..5485
                     /locus_tag="KRH82_003697"
     CDS             4754..5485
                     /locus_tag="KRH82_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656945.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            5519..6478
                     /locus_tag="KRH82_003698"
     CDS             5519..6478
                     /locus_tag="KRH82_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8656946.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(6576..7172)
                     /locus_tag="KRH82_003699"
     CDS             complement(6576..7172)
                     /locus_tag="KRH82_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBG8656947.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
BASE COUNT         2695 a          782 c         1358 g         2371 t
ORIGIN      
        1 atcaaaatta ggaattgtaa aaagaaggaa aaaataggat gttattttaa tagattaaga
       61 tttaaggtat tgtaatttat atataagata acgattgctt gtagatttaa attactttaa
      121 gaggagggat attatatgat gccattgata ttatcaaata caggtgaaga agtagttata
      181 aagaaaattt cgggaagtga taagacgagg acttttttaa atagtatagg ttttgtagtg
      241 ggtacaaatg ttaaaatagt ttctaagata gatggtaact taataataga cgtaaaagat
      301 actagagttg cattagataa aaaaatggca agtagaataa taatataggg aggtaatgac
      361 atgaacagac tgaaggatat taagtgtgga gagactgtaa aagtcaaaaa gttagaggga
      421 gaaggagcta cacgaagacg tataatggat atggggatta caagaggtgt taatatattt
      481 ataagaaaag tagctcctct tggtgaccca attgaggtaa cagtcagaga ttatgaacta
      541 tcaattcgta agtcagatgc agaaaaaatt attgtggaat aataaagatt aattagagta
      601 gggttaatgt aattatataa tgagaatgat tttctgtatc acaaacagtg atgtatttaa
      661 ataataatgg agggaatgga aatgtcaata aaaataggtc tcataggaaa tcctaactgt
      721 ggtaagacaa caatgttcaa tgggcttaca ggatcatcac aatatgttgg taactggcca
      781 ggagtaacag ttgaaaaaaa aggtggaaaa ttaaaaggaa ataaagatgt ggaaatagta
      841 gatttaccag gtatttattc tttatctcca tatacattag aagaagtagt tacacgtaat
      901 tttatgctag atgataagcc ggatgcagta ataaatattg tagatgcatc aaatatagag
      961 agaaatttat atcttacaac tcaagtttta gagctaggta taccgaccgt tatagctctt
     1021 aatatgatgg atattgtaaa taagaatggt gataagataa atattaaaga actatctgaa
     1081 gttataggtt gcccagtggt agaagtaaca gcagttaaag gtcaaggaat tatggaggct
     1141 gctgaaaagg cagttgaact tgcaagtagt aacaataaat taaatttcaa attacccttt
     1201 gttgatgaaa gtaaggatgc aatagaaaaa attgaaaaaa taatagaaga aaagactcca
     1261 tatatagatg tagaaacacg ctggttagct ataaagctat ttgagagaga tgaaaatgtt
     1321 atacaaaaac ttgatatttc taaaacaata ttgaatagta ttgaagaaat aactagaaat
     1381 tgtgaagatg aattggatga tgatagtgaa agtataataa cagccaatcg ttatgaattt
     1441 attagttcaa taatttcaag tataataaag aagaatcgaa aaggtaagga aactgtatca
     1501 gataagatag ataagattgt aacaaatcgt atactagcat tacctatttt tgcacttata
     1561 atgtggggag tttactatat agcagtaagt tcattgggta ctatagcaac tgattggaca
     1621 aatgatgtac tgtttggaga aattattcaa ggcaatgtaa gtaattttct agcttcttta
     1681 aatgtagcag agtggttaca aggacttgta gttgatggtc taattggtgg agttggagca
     1741 gtactaggat ttgtaccaca aatcatgctt ttattcttat tattatcaat attagaagat
     1801 tgtgggtaca tgtcacgtgt agcttttata atggatagaa ttttccgtaa gtttggtctt
     1861 tcaggaaaat catttatacc aatgcttata agttcaggtt gtggagttcc aggagttatg
     1921 tcaactcgta ctatagagaa tgatagagat agaaaaatga ctattatgtt aactacattc
     1981 attccatgtg gagctaagat tccaataata gcattatttg caggggcatt atttggaggt
     2041 gcttcatggg tagctccatc aatgtatttc ttaggtattg caatgataat catttgtgga
     2101 attatattaa agaaaactag tttatttgca ggagaaccat ctccatttgt tatggaatta
     2161 cctcaatatc atattccaag tgcaaaaggt gttttaatac atatgtggga tagaggaaaa
     2221 gcatttataa tcaaagcagg aacaattata tttgttgctt gtggagtaat ctggttctta
     2281 caatcattta attggtcatt acaaatggta gatgctggag atagtatatt agctagctta
     2341 ggaaatatag ttgcaccaat atttgctcct cttggatttg gaaattggca atcatcagta
     2401 gcaacagtta caggtctagt agctaaggaa aatgtagttg gaacatttgg agttttattt
     2461 ggtatatcag atgcaacaga gcaagaccca acacttcttg cttcagttgc aagcatgttt
     2521 acagtagcta gtgcgtttgc atttatggca tttaatatgc tttgtgcacc ttgttttgca
     2581 gctattggag ccataaaaag agaaatgggt tcatggaaat ggacatggat tacattagga
     2641 ttccaaactt taacagcgta tataattgct cttcttataa atcaagttgg aagtttagtt
     2701 ttaggtactg gaggaagtat tgctggggca ataatatcta tatttatagc agtagcagta
     2761 gtctttgtag ttttaactta ttcaaataaa aatatgaaaa aagaaaaaat gggtaaatta
     2821 agttatatga aaaattaatt catataaata aggagtgatg aatatggcta catttattat
     2881 agcagctatt gtagtagtat taatggcact agctgtaatg tatatggtta aaaattcaaa
     2941 aaagaatggt agcagttgtg gatgtggttg ttctggatgc tcaagtagta agagttgtca
     3001 tagcgctaag agataaatag gataagagcc tgataaaaag ttaaattgct ttattatcag
     3061 gttcttattt tttgtataaa taacaaattt catatttgaa gtaggttaga ctatgctgta
     3121 attttactgt ataattatat ataaatatat gattaggagg gattattgct aaattaagca
     3181 atataagtga atattatgtt taaatttgat gttacaaacg agcttatgtg tatagcaagg
     3241 ggaagtggta aattttttgc aaaaaaaggt gctatggtag cctttaaagg aaattttaat
     3301 tttgaaaaat tgctgttagg tccaagtaat ggcggtggat tgggaagagc attattaggt
     3361 catgttcaga ggtcattgac aggagaacaa atgccaataa tggtggttga aggtgaaggt
     3421 gaaatttacc tagctcaaaa tgcttaccat gtagatgtaa tatcaattga cccaggtgat
     3481 tccatttatg ttgagagtga aaacttattg gcattttctg aacaattaaa ttacagtgta
     3541 aaattgattg gttcaggggt aatatctcaa aaaggtcttt ttactacaca tttagtaaat
     3601 aaaacaggtc aaaatcaaga tgttgctata ataacagatg gtaatcctct aattcttgaa
     3661 ggaccttgtt gtgttgaccc agatgcatta gtagcttgga ctggaagaga accatatcct
     3721 aaagtatcaa aactatcatg gaagactttt attggtcaga cttcaggaga atcttatcat
     3781 atggaatttg ttgaacctgg acaaatagtc attatacaac catctgaaag attgtctggc
     3841 ttaaaaacag attctacacc ttctgataga atgagttcag gtggattaag acttggcata
     3901 gattaaatct tatgatatag cttaattatt atttaagata ttaaaaaata aaaagggtag
     3961 cagggataga tatgttaaaa ggagttttat atgtttgaga aaattcataa aaggcttaaa
     4021 ggatattata tttttttaat aattttaatt ttatggaaga tagtatgtgt tttgggtata
     4081 tggagtagct atattctgcc tcctcctgaa atagtcttag atacttttat aaaaatgata
     4141 tatgacggtt ctattttctt aaatgtttat gccagtgtaa gaaggatatt aataggtttt
     4201 ttaataagtt cattgatggc tataccactt ggagttttat ttggagtaaa taaaaaaatg
     4261 tatgaatatt tcaaaccact atttgaattt atgcgaagta cacctccact agctttggtg
     4321 ccaatgctta ttttatggtt tggtataggt gaagaatcta aaattataat tattattttg
     4381 gcatcctttt ttccaatatt tttaaataca ttgaaaggta taaaaaattg tgacaataaa
     4441 ttaatagaag taggtaaatc ttttaattta tctaaaaaga gaatttttta taaaataata
     4501 atccctaatt ctatgctgga tattgttgtt ggacttagtt tagggcttgg gtatagtttt
     4561 agggctataa ttggagcaga gcttattgca gcttcttcag gactaggata tttgatttct
     4621 gatggaaaag atatgtctag aactgatgtt gtattggtag gaatttttgt tattggattt
     4681 ttaggtatac tttcagatta tctattttca aagataataa caaaatttag caaagggaag
     4741 caggttgatt taaatggtta gaagtggatt tttgctagag aatatatata agaaatattt
     4801 agttgataat aaagagcatt tagttcttga taatatatct ttaaatatat ctagtgaaga
     4861 gataactgtt atattaggtg aaagtggatg tgggaaaaca acgctactta gaattttagc
     4921 agggcttgaa aatgctacta gtggaaacat atattttttt aataatgata aaaagtgtac
     4981 tccaaaagta ggaatggtat ttcaagaaag tagacttatg ccatggctga atgtaagtga
     5041 aaatatactt ttacatactg aaaaagataa tagaaataaa gttgatttag acaagtattt
     5101 aaaaatgatg aagcttgaaa agtttaaaaa ctcatatcca aatgaattat caggaggaat
     5161 ggctcacaga gtaagtatag caagagcact ttccttcaat cccgatattt tgctgatgga
     5221 cgaaccattt gcagcactag attacttcac aagaagaaaa atgcaaaaag aagttgtaaa
     5281 tatccataaa aatactaaaa aaggtgtagt atttgtaact cacaatattg aagaagctat
     5341 ggaaatagca aagaaaataa ttgtttttag taaaaataaa aggattaaac aatttagtgt
     5401 cgaagatgaa tataatagag atttaactaa aaactattat ataaacttga aaaaagaaat
     5461 attaagggaa ttgggggagt tttaattgat taaaagaaac aaaaagattt tagcagtaat
     5521 gacatcttta ataatggtgt tggttgggac tgtaggatgt tcaacaacaa atgataagaa
     5581 agatgaacct gcaaaaaaag aggctagttt acctaaggaa ataaatttaa cttatgtaaa
     5641 atcaccactt aatgttccta gtatattaga aaaaaaggat gatttatttg gaaaggaatt
     5701 taaaaaggac aatataaaag tcaatttcca tgaattgaca acaggaccag agcaaactca
     5761 agcattagca gcaggtgagc tagacttttt acatgcatta ggaggaacgt ctgcaataat
     5821 agctgcatca aatggtgttg gtcttaaaat tacgaatatt tatagccgtt caccaaaagg
     5881 atatatgctt ataactaata atgataatat taaatctata aaagacttaa aaggtaaaaa
     5941 aattgtaggt ccaaaaggga ctatacttca tcaactgttg attgctgcac ttgctaaaga
     6001 aggctatact atagatgatg ttgaatatgt aaatatggat attcctagtg ctgcttctgc
     6061 attagaaagt aaaagtgctg atgtagcaat gcttgcaggt ccagtggcat tgaaaacgat
     6121 aaattcaggt gccaaaatga ttgtaaatgg agaaggatta gtaagtggaa taatagttac
     6181 tgctgtaagt gatgactttg ctgaaaaata tcctgaatta gtaaaaagat ttatgaaggt
     6241 tcatgaagaa actttaaaat atatgaatga aaacaaggat gaagtgatgg atgttgtatc
     6301 taaagaagtt ggtttatctt tagatgaaac aaaagaaatg tattcttggt atgactttag
     6361 ttctaaaata acggacaagg atataaaaga attagaagat acacaggaat ttttgatgtc
     6421 taatggaatg caacaaaaga aaataaatat taaagatatg ttgtacaatc aaaattagaa
     6481 tactttaaaa tattaaagtg gaaaatacac ccttatttat tatggaaact gtatggtaaa
     6541 agagggtgta tttttattat tatacaaaaa cacaattaaa aacagcttac tattttatct
     6601 acacttatgt agtctagtaa ttttctcatt ttcttacggt gaagtaaaaa cttcgaatat
     6661 gtgtcctcgg attgttttgt gtcaccataa actttccaat atttaatcat agaaacttca
     6721 taattactat atcccataaa tccaatcaca tctttaagag gatatcctaa aaaaatacct
     6781 atttcatcag gaaaaacatc actcttaagt ttatctacta aatgctctaa ataagcatta
     6841 acattcgtat tttgtttgta tcctaaaaac tttaaaaagt ttactgtttt tttacatttt
     6901 aatttttctg ataatgcttt tttatttaca aataagattt ttaatccctt tttttcttta
     6961 tcaataacta taaaatctat tttcttacat ttatatagat atttataaat atcattaatt
     7021 ttttcctctc tatttacatc agtaaacgaa atatttatta tttcagcagg tttagagcct
     7081 aaaaagactg gacctaaaac ttctaaaagc cattttatat atgatgattc aattttattt
     7141 ttacaacaaa attgtgaatt acaacaagac ataaaagata acctccttca aatgaaaatt
     7201 aatatc
//
LOCUS       DAEOTL010000139         6940 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEOTL010000139 DAEOTL010000000
VERSION     DAEOTL010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6940
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.141"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            112..2469
                     /locus_tag="KRH82_003700"
     CDS             112..2469
                     /locus_tag="KRH82_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBG8656948.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMVLAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2555..2872)
                     /locus_tag="KRH82_003701"
     CDS             complement(2555..2872)
                     /locus_tag="KRH82_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBG8656949.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            complement(3456..4727)
                     /locus_tag="KRH82_003702"
     CDS             complement(3456..4727)
                     /locus_tag="KRH82_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBG8656950.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            4939..5178
                     /locus_tag="KRH82_003703"
     CDS             4939..5178
                     /locus_tag="KRH82_003703"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656951.1"
                     /translation="MECYLKRTLIIFSEAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYVGVLKLINYSILIL"
     repeat_region   5374..6784
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5374..5402
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
BASE COUNT         2567 a          783 c         1027 g         2563 t
ORIGIN      
        1 ctatagaata ataaaatata aaaattgaga attttataat atatttgtag atttgagtat
       61 aaaaaagtgc taagttgaaa ggagtaaaag ctaagttgaa aggagtaaaa tatggataag
      121 gttaatttag aaaggtatag ttgtgatata aatgttggtt taaataaaaa tcaacttcaa
      181 agtagaatag atgataattt aattaatgca tttgataatg gaaaaaccaa aacatataaa
      241 caaattttta aagacaatat atttacactt tttaatctca taaatattgt tttagtctgt
      301 ttattagttt cagttggttc ttttaaaaat accttattta tatttattgc tgtaattaat
      361 actattatag gagtaataca agagataaga gctaaaagat tattggacaa tctatctgtt
      421 atagtttcaa ataaggtatc tgtcataaga gaaaaagaga aaaaagagat tgatgtacaa
      481 gaattagtat tagatgatat tatgatttta aaaacaggta atcaaatttg tgcagattca
      541 aaagttttaa atggaaaatt agaggtaaat gagtccttgg ttacaggtga atctgatatt
      601 attataaaaa ataaaggcga ttttttatat tctggaagtt ttgtagtttc tggagaagct
      661 tttgtaagag ttgaaaatat aggaaaagat aactatgcaa ataagatagc taatgatgca
      721 aagatttcta aaaaacataa ttctcaactt agaaattcat taaatgcaat attaaaaatt
      781 gtaggtataa taataattcc tctaggaatt atattgtttg caaaacaaca ttttggaaat
      841 ggagattcta tagctacatc tgtagtaggt acagtggcag ctgtaaatgg tatgatacca
      901 gagggattaa cattacttac gagcattgct ctagctgtag gaactataaa acttgctagt
      961 cataaaactt tagtgcaaga actgtactgt gtagagactc ttgctagagt tgatacacta
     1021 tgtcttgata agacaggtac aattacagaa ggtaaaatgc aagttgatga tatagtaatg
     1081 ttggaagaag tggatattaa tgaaataatg gggaatatat gtaattctct caaagatgat
     1141 aatgcaacac taaatgcaat aagagataag tataatgttt tagatacgta taaagctaag
     1201 aatttaatac cattttcttc agaaagaaaa tacagtgggg ttacctttga aaataaaggt
     1261 acatatttat taggtgcatt tgagtttata tttaaggaaa aaaataaaaa acttaggata
     1321 gaagttgaaa gatattctaa aaaaggaaac agagtaatag ttttagctca tagtgattct
     1381 tatatggaag ataataatat tcctgaagat ataaagccac tagcttttat attgatattg
     1441 gataaaatta gagatgaagc taaggaaact ttagaatttt tttacaatga aggtgtagat
     1501 ataaaaatta tatctggtga caatcctata acagtaagtg aggtagctag aaaagcaggt
     1561 cttaaaacag ctagtaattt tattgatgca acaacactta aaaatgatag tgatatatac
     1621 aaagcagttg ataaatacag tgtttttgga agggtaagcc cacaacagaa aaaacaaatg
     1681 attttagcat taaaaaaaca aaatcataca gtagctatga ctggagatgg tgtaaatgat
     1741 gtgctagcac ttaaagaagc ggattgtagc attgccatgg catctgggag tgatgttact
     1801 aagaatgtgt ctaatttagt cttattagat tcaaactttg catcaatgcc aaaggttgtt
     1861 atggagggaa gaaaagtaat taataacatt caaagagcat cttctttgtt tttagtaaag
     1921 acaatttttt cattcttctt gtcgttatta acattattct tcttcagtag acagtatcca
     1981 tttgttccta tacaattatc actcattggg gctgtaacag tgggtatacc atcattcttc
     2041 ttagctcttg aagcaaacaa aagtagaatt tcaggaaatt ttttactcaa tatattaaaa
     2101 aatgctttac caggagcact atgtgtgaca gtaaatgtaa ttattgttta caatatagtt
     2161 gaatatttag gttatagttc aagtgtattt tccacaatgt gtgctatatt aactggtgta
     2221 tgtggtcttt taatattaag acaacaatgt ttgccattta ataaagaaag attattttta
     2281 atagtaagta tgactattgc atttgttatt gggattctat ttttaggtgg attattctca
     2341 tttgtagcat tgagtagaga attaattctc ataactatgg tattagcaat attaatgcca
     2401 attatgataa aagttatgtt atttgtctta gatgagatat tagagacaat tgttccagat
     2461 ttaaattaat tttaaaatga tataaataag agcagtttta gttgaactgc tctttttaga
     2521 tgtgtttaat tttatgtaag aatatgtatt tttattaatc agctatatat gagcaacagt
     2581 agtcaacaac ttcattaacc tttaagtcaa aacttgaatc actaggaaca ttaaattttt
     2641 gcccttcttt ataagttaca aactcattgc ttccaggcag ttttacatcc atacttccag
     2701 caagcatctc cattatttct tcttctctag tagaaaaagt gtattctcct ggcaacatta
     2761 atcctaaagt ttttctttct ccattaggca gtattattac tctgctactt accttaccat
     2821 caaaataaac gtttgccttc tttactgcag taacattctt aaattcactc attagataaa
     2881 acctccaaaa ttatttgtac atatatatta tataaaaata atgtaaaaaa tgctatatat
     2941 ttacaaaaaa atttagtatt tattaaaaaa attaataaga ataaaaaaga gatgaaattg
     3001 cttaaattga taaaaaatat aaaataaatt gcaaagtaag caagaaaaga ataagttgaa
     3061 gagttatata ttataaatat taaaaatttt agtattaata aaagagatat tacattaata
     3121 tgaaaatata ggagattaga agtgtttgat aattacagta catgttagat atatcattgt
     3181 aaattaacat agctttgaat ataataatgt tcaaaaggca atatttttga ggtctgaatc
     3241 caataataat atagtcttat gattgtagat atcaaaaaat ataagttact aagaatacgt
     3301 tttgtagatt tatatatgat taataactaa agctataaat aaacaaaata aaaagagtat
     3361 gtttcaacct atagctttta gatttaaaat atactctttt attaattata gttgtataaa
     3421 ttaaccataa tatataatta aaatttttat tataattata tattaggttc ttcaattagt
     3481 tttccacata catatctatg aatgatattt ctatcatcac caacatagat aaatctttca
     3541 agtctttcaa gtatagaata attgtcatga tttaaatttg aatcatcaat aatcaatgca
     3601 tcaaaatcat aaccttcttc aaagctacca acttttccaa agaaacttcc accacttttg
     3661 gttgcaatat aaaaagcctc agataaagat aagaaattat acttcttacc agaattaacc
     3721 caatataatt tagataattg tattgcagat accattgctt taaatattga caatgtatgt
     3781 ccaccgctta tatctgatcc aagtgctaat ctaatattat tatcgattaa ttttctgata
     3841 ggcatagcac cactaccaac attaaagtta gaagctggac agtgaactgc cataacatta
     3901 ttttctctca ttaaatctat ttcatcctga gaacaatgaa cacaatgagc cattaaagta
     3961 ggagtttgac caaataaatt atatctatta tatgcatctc catagaattt agattcaggt
     4021 tctagacttc taacccattc aatctcatca taattttcag ataagtgtga ttgaatagga
     4081 atattatatt ttaaacataa atctcctaaa ccttttaaaa gttcacttgt acagcttggt
     4141 ataaatctag gtgttattat tggttttaca atagaatctg tatcactata cttatttata
     4201 atttcttctg tatcagtaat agaatcctga gtgttttcta ataaagtatc agggcaattc
     4261 atattcatat ttactttacc aacgtatgct ccaagaccaa cttctttgaa tatatccata
     4321 agtttcatag aggcttcttt atgtactgtt gcaaacactg ctattcttgt agttccagat
     4381 ttccaaagtt cttttacaaa ttttttatac atttttgttg catattctat atctttataa
     4441 tttgattctt ctggaaatgt ataagtttca agccatggca aaagctcttt atccatagcc
     4501 attccaagat ttttaaattg agaggcatgg gcatggaggt cattcatacc aggtattata
     4561 agcttatcag tgtaatctac tacttttagg tttttgtatt ccttaggtat ctctttaaat
     4621 attcccttta ctttaccttt ttccagtata atataactat tttcaaatac tgtgaaagtt
     4681 tctgaagttt ttgtaaaaat tatatttcct tttaatactt ttaacatata ggtctcctta
     4741 gttttaaatt tgttttaata tatgtaggta aaattttgtt ttacaaatca aaattttacc
     4801 acatgtatta tatcaaatct aaactataaa tactattaga taatagcaaa tattagtgca
     4861 atacagttgt ttactattat tatatataac tgacatttaa gtgacattta agaaaaatat
     4921 aatgcctact tacataaaat ggaatgttat ttaaagagaa ctttgattat attttcagaa
     4981 gcttttttat ccatatcgtt taaaacaaga aaatatctat tcatagttat ttttatatta
     5041 gtatgtccta atctttcaga gatgattttt atattagttc cagctagaag aagaattatt
     5101 agaatagata atatagtaag tatttacaaa tatgtaggtg ttcttaaatt gataaattat
     5161 tccattttaa ttttatagtt tgaattttat gatataataa aaatatataa attttgcagt
     5221 gagcgatatt tttgataaag tagggtttaa cagttgcaat gtaagggatt gagggtgtgt
     5281 gataaatgtt atcaattgca ctactcatgg ttcactgcaa atttgagaga gttgtatgtg
     5341 tgtaagtact gaaaatactt agtttatttt ggggttttat attaactaag tggtatgtaa
     5401 atcaaagaag ctccacccca tctgtttttt attatagcgt tttatattaa ctaagtggta
     5461 tgtaaattgt tttccatgaa catttcgagc tgacttttat tgtgttttat attaactaag
     5521 tggtatgtaa ataacttctt gttttttctt taaaacacgt acttggtcgt tttatattaa
     5581 ctaagtggta tgtaaataaa tcaatgccaa ctataggaac gtcgggatta attggtttta
     5641 tattaactaa gtggtatgta aatggagtat aaggtaaatc gtaagcaact ccagaaagag
     5701 gttttatatt aactaagtgg tatgtaaatg aattacaata ttatctccag catcaagact
     5761 aggatgtttt atattaacta agtggtatgt aaatctgata gaaaaagaag attatttgaa
     5821 agttgagact agttttatat taactaagtg gtatgtaaat aaagattgca atagatttcc
     5881 tgttaaaata ggtacaggtt ttatattaac taagtggtat gtaaatactg aacctactag
     5941 cattgtaggg ttgaagtcta caagttttat attaactaag tggtatgtaa attctttttc
     6001 aaattgcata gttggttata cttattataa gttttatatt aactaagtgg tatgtaaata
     6061 aatatgtaag ttttaattta aaatgatatt caactgtttt atattaacta agtggtatgt
     6121 aaataatatt tagagatggc gtagagtgtt aaaagtttca gttttatatt aactaagtgg
     6181 tatgtaaatg aaataataaa tagcattgtc gaatggtttg caagccgttt tatattaact
     6241 aagtggtatg taaattatag ctaattatta gattcaattt taatttcgtt aagttttata
     6301 ttaactaagt ggtatgtaaa tattgcaaca cttcatcagt tgataaatat agtatattgt
     6361 tttatattaa ctaagtggta tgtaaattta tacatatttg tagctccttg ctgaactgtt
     6421 gcagttttat attaactaag tggtatgtaa attggttaaa tctccaacag aacatttatc
     6481 taaattacaa gttttatatt aactaagtgg tatgtaaatc ttgttaatgc aaataaacaa
     6541 catagcacta ttaatagttt tatattaact atgcggtatg taaatagggt ttctgataaa
     6601 atcttcaaac atgtaaaata tgtgttttat attaactatg aggtatgtaa atcttatact
     6661 tagttagaac tatatatcga cacaaatatg ctttatatta actatatggt atataaattg
     6721 caatttttat tcgttgtcca atctctttga aatttgtttt atattaacta agtggtatgt
     6781 aaatttgcaa caagtatagg taaaataccc caataattta tacagcattt tctcctttaa
     6841 aatataatta ttttttagca tttgtagtaa ataattacca gataacattg actttagttt
     6901 taatgattaa aatataaaag tagaataatt ataaaaagta
//
LOCUS       DAEOTL010000140         6897 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEOTL010000140 DAEOTL010000000
VERSION     DAEOTL010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6897
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.142"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..1432
                     /locus_tag="KRH82_003704"
     CDS             <1..1432
                     /locus_tag="KRH82_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBG8656952.1"
                     /translation="LFIFVILIIPLVNTVLISGFIGKIQIPEYILDYIKSDIILNIIY
                     MIFLLIIYISVIRWIFSIHEITLNTENFKRARKESVNLIKGKIIRTIIYSLILSLVVA
                     IIGYAIYHSGIIFIGIWTKYCTDMEFLKNVFINRCIAFEEYFRLILSIFIFILDIGFI
                     SATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILLISYIESVAFSSHINGMFNTSFS
                     FYTTAIAHRAGAEMAPENTLAAIKEASHAKADYAEIDVQEAKDGELIVLHDSNFKRTT
                     GVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVGEKIPTLKEMIKYSKGKVKLLIE
                     IKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKTILQKVKKLDENLLTCYFMAIAY
                     GDFSKLNYVDMYGIESTFVNKTVVEKIHKMNKKIFVWTVNSDSLIEKMLDLNVDSIIT
                     DNPYLIESAIYWKKNGFISQVSDYLF"
     gene            1754..2338
                     /locus_tag="KRH82_003705"
     CDS             1754..2338
                     /locus_tag="KRH82_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBG8656953.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
     gene            complement(3441..3617)
                     /locus_tag="KRH82_003706"
     CDS             complement(3441..3617)
                     /locus_tag="KRH82_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656954.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            4192..5214
                     /locus_tag="KRH82_003707"
     CDS             4192..5214
                     /locus_tag="KRH82_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656955.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFIAPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGTMSLCFLVIK
                     SDYISR"
     gene            5228..6115
                     /locus_tag="KRH82_003708"
     CDS             5228..6115
                     /locus_tag="KRH82_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656956.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDINSIVLRIVSEDILSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            6121..6894
                     /locus_tag="KRH82_003709"
     CDS             6121..6894
                     /locus_tag="KRH82_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656957.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNEPIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
BASE COUNT         2730 a          638 c         1053 g         2476 t
ORIGIN      
        1 attatttata tttgtgatat taataattcc attagtaaat acagttttaa tttcagggtt
       61 tataggaaaa atacaaatac cagagtacat actagattat ataaagtctg atataatttt
      121 aaatataatc tatatgattt ttcttttaat aatatatatt tcggttatta gatggatttt
      181 tagcattcat gagataactt taaatacaga aaattttaaa agagcaagaa aagaaagtgt
      241 taatcttata aagggaaaga ttataagaac aattatttat tcattaatat tatctttagt
      301 agtagctatt attggatatg cgatttatca tagtggaatt atatttatag gcatatggac
      361 taaatattgt actgatatgg aatttttgaa gaatgtattt ataaatagat gtattgcatt
      421 tgaagaatat tttagattga ttttatcaat attcattttt atattggaca ttggatttat
      481 ctcagcaact tattatcaat ataaaggagt aagtatttct aaaaataata ttaaaaaaga
      541 gaaaaaatct atatcaaaaa ttgtttttaa tttagtatta atattattga tttcttatat
      601 agagtcagtt gcattttctt cacatataaa tggtatgttt aatacgtcat tttcatttta
      661 tacaacagca attgctcata gagcaggagc tgaaatggct ccagagaata ctttggcagc
      721 aataaaagaa gcttcacatg ctaaagctga ttatgcagaa atagatgttc aagaagctaa
      781 agatggagaa cttattgtac ttcatgattc aaactttaag agaactacag gagtagataa
      841 aaatgtttgg gatgtaaatt ataatgaagt aaagacatat gatgcgggaa gcttttatta
      901 ttatggaaaa ggttattatg atgaaaagtt tgttggggaa aagataccaa cactcaaaga
      961 aatgataaaa tattctaaag gtaaggtgaa attattaata gaaataaaac ttaatggaca
     1021 tgaaaaggga gacgtagtaa aaaaagttgt tcagttaatt aaagaaaata attttgaaaa
     1081 tcaatgtata gttgcatcta tggataaaac tatattacaa aaagtaaaaa aactggatga
     1141 gaatttattg acatgctatt ttatggcaat tgcatatggt gatttttcaa agttaaatta
     1201 tgttgatatg tatggaattg aatcaacttt tgttaataaa acagtagtag aaaagattca
     1261 taaaatgaac aaaaaaatct tcgtttggac tgttaatagt gacagtttaa ttgagaaaat
     1321 gcttgaccta aatgtagata gtattattac agataatcca taccttatag agagtgcaat
     1381 ttattggaag aaaaatggat ttattagtca agtgtcagat tatttatttt aaatattcta
     1441 taattgtatt atccagtaaa agagatatta ttaaaatcaa taatatctct ttttaacata
     1501 aataaggttg ttaaattaag gttattctta taaaaattgt gcttatcagc tataaacaag
     1561 gaataaaagt gaaaaaattg ctctgagatt attacagtta aaagagtttt aagatgacag
     1621 agagatagat tgtcaactgt atatttaata aatcttgtta tttattaaat tttatataag
     1681 taaaatatat aaattaataa atcttatgct agaatatata tgaaaaacaa tataaatttg
     1741 gaggattaaa aacatgacag agcgagaaaa aatgttggca ggagaacttt acgattgtgg
     1801 tgatattgag ttgttaactc aatggcataa agcaaaagac ctagtaagag attataacca
     1861 aacagattcc tcggatttgg aaaaaaaaga aaaaatatta aatgagttac ttggtggtaa
     1921 gggtaaaaac ttatggatta ctgcaccgta ttatgtagat tatggaaata atatttattt
     1981 tggaaataat tgtgaagtca atatgaattg tacgttttta gatgataata aaattatcat
     2041 tggggataat gcactaatcg caccaaacgt acaaatatat actgcatttc atccaactaa
     2101 tgctggtgat agatttggta atgccaaaga agatggttca tttgaatttt gtaaaactca
     2161 aacagctcca gttactattg gagataatgt ttggattggc gggggtgcta ttatcatgcc
     2221 aggtgttact attggagata atgtagttat aggtgcagga agtattgtta caaaagatat
     2281 tccaagtaat atgattgcat acggaaatcc atgccgtatt attcgagaaa ataaataaag
     2341 ttaaattttc ttgcaaaatc tcaaaaaaca cctttcttac tttatacata gggtattttc
     2401 taatactttc acatccatat tcatttgtta aatttttgtg gaatgtagtt tttatcactt
     2461 ctatcttaca tttccaccat ttttttataa aagtcattcc tttatatatt tatttataat
     2521 agtatatatt ctatttgatg tttgaataag cacttatttt taagtaaaat actaactttt
     2581 aggttagtat tttactatag tatgatgatt aagtaagaat aaaatactat aatacataaa
     2641 gcttaataaa tataattttt attttactta gatattttct tttgattagt aatcaaaagt
     2701 ggttataatt tttttaatta ataagagtaa catttatttt atgaaagagg attatattaa
     2761 tatatattta aataggaaaa attgtaaaaa gcataaaaat aatataatta attaatgaga
     2821 taaaagtgga taaaaatatt gggagtttaa tttttgtgaa attaaaaata ttaaagataa
     2881 tctacaaata tagaatatat tctaagacga atttttataa ttactaaata aaataaatta
     2941 atcaatatag ttttttaata taaacaaaaa ataaaaaact tatataaata aaatgcttgt
     3001 ttttcttgta ttatttatat aaatattgaa atttgtctag ttatacgttt ttattgacca
     3061 gttatgcagt tgatattgaa tattctaaat attggtgtta ttttataggt ggtttaaaca
     3121 tattaggggg attttatata tgatttgtat gatttataga gaatgtataa aatagtaaag
     3181 gtttagagcc atgtttagtg gattgcagaa tatgcatata gaatgattct tgtaaattaa
     3241 gttagacata ggaaatatat aatttgtatt ggatgattga ttttatggtg tatgctttta
     3301 acttctataa tgggaaagta aagatgtact cccaatacat ctttacttta gcagaagtta
     3361 tagttactta taaagtacaa aaaattatat atttattaga gtagataaat ctaaaaaggt
     3421 ttttctagaa aaatttagtt ttaattgtat ctacttacta ataataagac ttgatgtaag
     3481 caggtttcaa ctaccgtttc tccatattct gatataaaat catctaactg tgtatctaaa
     3541 aaattacaat aatcatatga actactgatg taagcagtta gtatatgtgt acatttgtct
     3601 atttctccaa taaacatatt atccatcccc ctaaaaaatt tagtaaaaat aaaaagtcgc
     3661 attctattag tcaattaaca taatttataa aattttttag tactagtttc tataacttaa
     3721 ctccttaagg ttaaatattc ccagttttac caatttagtt ttattctaca agtatataat
     3781 actagaagat gcttcattat tcaacatgct tgtttgagaa tagaaaatat tctaaaatta
     3841 taattgtttt taaaaataag attcaagata aataaagtta tatgcaacta tttaataatc
     3901 tttccataat aaggacagta ggttctattc ttaaaaaact ccatctttaa atttaaagaa
     3961 taactacaat ttgaacaaca ataaaatttc caatcaataa aaatatcaaa aataataaaa
     4021 ataattgaaa atgtataatt tcccagaaaa ataataaatg taactccaat aataaacaca
     4081 cctataaatt ataaaataat ttaagcttta tttaaggtta gtattatatt tatataagat
     4141 ttaagtttta atatatatgt gtaattaaaa tgatttagga ggagaaatat attggtaaat
     4201 tgggaaataa aaaaattggc taaatctaag agtatgttta tatctctagg catattagtg
     4261 ttaatactaa tgattagtat ctttattgcg cctgttttag aaacagaaag ttattatata
     4321 gataaagaaa aaggacgtat agaagatacg agaagtggta tcgacatagg taatgagaaa
     4381 tttcaaaata agattaatgt tttaaagcag ttttcaaatc aaacagatac aggtgaattt
     4441 tctaaaaaaa ttgaattaat gtcaaagaaa aaacttgata atctaagtgt gaatgaatat
     4501 aaggatatta gtttttggaa agtatttaac tatagagtta caaattcact tataaatgta
     4561 ggaatgttaa tcattatatc tataattata tccaatattt acgtagatga agtcgttact
     4621 tcggtaaaag atatcatact atcatcaaaa gagaagaaaa aagcattaaa gtctaaaata
     4681 tttgttgctt tattagttcc attagtaatt tattctgttt atttaatggg aatatttatt
     4741 ataacttgta tgcaacaagg agtacctgtt aatggagact tagaatcttt tagaatagta
     4801 gacaatgtag ttgcattgaa aactaattta agtataacaa agtatgtaat attaaatata
     4861 ggcatagagc ttttgatgtt tgaaggatgg gccatgatag ccatatttgg gtcttttata
     4921 agtaagtctt caatatcttc aataagtttt tttatattta ttatatctat aactaagata
     4981 atgtcggtaa tccatatatt acctaaaaaa ttactttcag ttgtatcaaa tgtaaattat
     5041 tatgatttga tatttggttt taataaaata ataggaaatt atctaggtga tattatgata
     5101 tttaaagtga atatagacat tgtcaatata gcaataggac ttttgatggc aatattgata
     5161 ggtactatgt cattatgttt tttagtaata aaatcagatt atataagtag ataaaagggg
     5221 agttaagatg aataaattag aaatagaaaa tctttcaaag atatatggta aaaaagtagc
     5281 aaacgacaag attacagtaa ctctggaaaa tggagtttat ggtcttctag gaccaaatgg
     5341 agcaggaaaa tctacattaa tgaaacaaat aacaacgttg ataaaacctg atgaaggtca
     5401 gatactttat aatggtgagg atatatttaa aatggatgct gattatagaa atattttagg
     5461 atatttgcca caagaatttg gagtttataa aaattttaca gcaaaagaat ttttacagta
     5521 tattggagct ttaaaaggtt taaggggaaa atatttaaat agtaagatag gagaattatt
     5581 agatttagta ggtctttatg atgtgagaaa taagtctata ggaaaattct caggaggtat
     5641 gaagaggaga gttgggatag cacaagtttt actaaacgac cctaagataa tagtccttga
     5701 tgagccaaca gcaggtcttg acccacaaga aagagctaga tttaggaatt taatagcaaa
     5761 aatgtctaga gataagataa taatactttc tactcatata atttccgata tagaatcagt
     5821 tgcaaaggaa acaataatga ttaaagatgg caaactccta atgaaaggaa cacacaaaga
     5881 catattaagt cacatggaaa ataaagtata taatgttcaa gttaaaaatg aatgtgaagt
     5941 tgatgatata caatctaaat ataaggttgt aagtattcaa agtgatatta attcaatagt
     6001 acttagaatt gtttcagagg atattctaag cgaggataat atacaaccag ttcaagcaaa
     6061 attcgaagat gtatacatgt tttattttga tttagaagat gcaagggagg tgtagtagaa
     6121 atgatgtatt tagttaaagc tgaaatgata aaaatattaa aatcaaagag tgtttggata
     6181 atttggctgt ttttaatatt ttttggattt tttctgatta gaaagtttga tgttttagat
     6241 acttatgcag atatatttta caagatagaa ggctcaatac ctctaatagg tttgataatg
     6301 tttataataa cttctggaaa ttacattaaa gaatatgatt ctaatatgac aggtttaata
     6361 aatacaacta aaaagggaaa aaaatcagta gtattatcaa aactagtagc taatggatta
     6421 attttatcta ttattaatat ttcttttata ttgttagtag gaattagagg ttttagtttt
     6481 tttgatttta aaaatttaaa tgaaccgatt cataacttat ggtactttgg aaatagtaat
     6541 ttaaatctta cagtaataca aatgtatata attgttatat tgactactat ttttgcttct
     6601 tttatatttg cacaaatagg cttaacactt tcatctatat ttaaatcggc tgtaattcca
     6661 tttatactag gtggattgat aatggcaatt ccatacttta gtgtaggttt tataccagat
     6721 aaagctataa aatttatgtc agtgactcca aattggatta tgatgagcca acaaatggtt
     6781 aagtataatg taccaagtat tttgatagtt ttttctatag taatctcaat tatattaatg
     6841 atagtgttaa ctaaaataac atatgaaaat tttacatcaa gcaaaaggtt ttaacta
//
LOCUS       DAEOTL010000141         6860 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEOTL010000141 DAEOTL010000000
VERSION     DAEOTL010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6860
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.143"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            5..1261
                     /locus_tag="KRH82_003710"
     CDS             5..1261
                     /locus_tag="KRH82_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBG8656958.1"
                     /translation="MRDLNVSEYLFIFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            1284..3365
                     /locus_tag="KRH82_003711"
     CDS             1284..3365
                     /locus_tag="KRH82_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBG8656959.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            3402..4487
                     /locus_tag="KRH82_003712"
     CDS             3402..4487
                     /locus_tag="KRH82_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBG8656960.1"
                     /translation="MRKYMNKFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            4541..5665
                     /gene="wecB"
                     /locus_tag="KRH82_003713"
     CDS             4541..5665
                     /gene="wecB"
                     /locus_tag="KRH82_003713"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBG8656961.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENIKSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLV
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            5743..6717
                     /locus_tag="KRH82_003714"
     CDS             5743..6717
                     /locus_tag="KRH82_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBG8656962.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNGKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQALENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         2855 a          642 c         1145 g         2218 t
ORIGIN      
        1 atttatgaga gatttaaatg tatcagagta tttgttcata tttagtctgt ttagtatatg
       61 gtctttattg cttataaata ttattttagc tatgggtgga tatatatttt attttaaaaa
      121 ctttgataaa gaaataaaag aaattgatga atatcctatg atatcaatac ttgttcctgc
      181 tcataatgaa gctaaagtga taggtagaac tgtggagtct ttgctattac tcaattatcc
      241 taagagtaag atggaactta ttgttataaa tgacaattct tctgataata gtaaagaaat
      301 tttagaaaat ataaaggata ggtacaacaa ttataatttc actataataa atacagatag
      361 tttaacaggt ggaaaaggaa agtctaatgc attaaatatt ggatatacga tttcaaaagg
      421 agattttata gctgtttatg atgcagataa cacaccagat aaaaatgcac ttagatattt
      481 agtacaaact atagtaatga atgatgaatt aggtgctgtt attgggaaat ttaggactcg
      541 aaataaaaat aaaaacctat taaccaaatt tataaacata gaaacattaa gctttcaatg
      601 gatgtcacaa gctggtagat ggcaactttt taatctatgt acaataccag gaactaactt
      661 tatattgagg agaagtatca tagaagaaat tggaggatgg gatagtaaag caattgcaga
      721 agatacagaa ataagtttta ggatatataa attgggatac aagataaagc ttgtaccaca
      781 atctataaca tgggaacaag agccagaaac tgttaaggtg tggataaagc aacgtactag
      841 atgggcaaaa gggaatatat atgtattaat gaaatatata aaaaatatat ttaaacaggg
      901 aagaaataag attgtgtttg atatagctta ctttttttct gtatattttc tatttttaac
      961 atctgtaatt atatccgata ttttatttgt tttaagtata tctaaactag tagaaatttc
     1021 tattccaatt aacttttttc taatatggat actatcttat cttttattta ttatagaagt
     1081 gagtataagc cttactatag aaaaaggtga agcaacaatt gaaaatatat tcatagttgc
     1141 aataatgtat tttacatact ctcaactatg gctgtttgta gctataaaag gaatgataga
     1201 gtatctaaaa gatataattt ttaaaagaga ggttaaatgg tataaaacag aaagattttg
     1261 attcatgtac aggaggaatt aacatgaaaa aatttattat atcaattata tctttagtat
     1321 tgtttttttc aaatatatca cttatataca aagtaaatgc tgatgagact aaagttaaaa
     1381 attataagtt tgaaagagat ataactattg atggtgttat aggaagtaat agtacttttt
     1441 ttgaagtaaa taaaaattgg gatattgaag aagttttatt gcatcttaat tttagtaaga
     1501 gccaaatatt aaatggagat gtttcaagtt taactgtatt gataaataat gtaccaataa
     1561 aatctattaa attaaatgct aagacaaatt ataaaaatac attagaagta ttagttccaa
     1621 aagattatat aattcaagga tataatgaaa taaaaataaa aacatacaaa acaatatctg
     1681 ataaaatttg ccaagatgat tccaatactg ggaactggat ggttattcac aaagaatcat
     1741 atatatcaat tagatataag cagaaaaagg tggaaaactc aataaatgaa tatccgtatc
     1801 catatgcaga aattgaaaat aatcataaat tagatacaac tatagtagta ccagataata
     1861 tgactagagg agagactaca gcagtgttta atttggcatc agcatttgga aaaataacaa
     1921 aaaatgatga tttaaagtta gatgttaaat tatattcaga aatgaaaaat tggtcagatg
     1981 ataatattat atatattggt aaacctgaaa atacagcaga agaaattttg gatattttaa
     2041 gtataaagga acaaacccta ttatcttcaa actgtataat caagcaagta gattcaccat
     2101 acaataagaa taagaagatg atggtggtaa ttggtagtaa tgaagatgat ttaataaagg
     2161 catcaaattt attaatagaa aatagacttt ctaaccaagt tttatcatca tcagtacttg
     2221 taaacaaaga gactaatata aaaattaata gggaacaaaa attaaattta ggtcatttaa
     2281 cattaaaaga cttaggatat tctgactttt tgttggaagg agcatttaat caacaagctt
     2341 tgtttgatgt caaaatacca acgggtaagg tattagatga tggttcaaag attatcttaa
     2401 atttaagata ttctgacaat ttagattttg aaaaatcttt agttacagtg tctataaatg
     2461 atgttattgt gggaagtaaa aaattggata ggtcacattc taataatgat aagttagaat
     2521 taaaaatacc taaagatata gataataaaa actattatca agttaaattg acatttaatt
     2581 tgagtataaa aaattcgaat tgtgttacta gagagagtaa taatccttgg gcatatgtat
     2641 caaataattc ttatttggcg ttatctacga aagaaaatga aaccttatct tttgaaaatt
     2701 atccgtatcc atttgttaga gatgatgaat ttaatgattt aactgtgata atgccagatt
     2761 attcagggtc acaagctatg acctggatgt ttagattagg tgttacttta ggtgcgaata
     2821 taaattcaca taatggaaat ataaatgtaa ttagaggaaa agaatttagt gacaagtata
     2881 aggatactaa tattgtagtt tttggagtgc cacataataa ttctgttata aagatgttaa
     2941 ataataattt aaatataaag ttcgataaaa attactccaa ttttatatca aatgataaga
     3001 taagctttat tgatgattat ggaaaaaata tttctaccat tcaattaata aaatcaccat
     3061 ataataatca aaaaaatatc atggtaatta gttcaatgaa tgaaaaaaac ttatatttag
     3121 gaatggatta tttgttgaat aaaagtaaag ttaatgattt aaaaggagat acattgataa
     3181 ttgatgaata cggagaggta gaagatttag cttataattt aaaatctaag aaagaagtaa
     3241 aagattcaag ttggaatatg agtataaata agacaactaa agtattttta atgatttctt
     3301 ttattactat aattgtagtc atgatattat caatgctata tataaaaaaa tataaaagaa
     3361 gataatatga taaatttatt attttaaaag aggtatataa tttgaggaaa tatatgaata
     3421 aatttaaatt aaaaagaagt attttaatct cattaataat cttaattttt atatttatag
     3481 tttactttgt aagtattgag ttaaaagata ggagtctagt aaataatcaa tataaaggta
     3541 agattaaatc ggccaattta tctgtagatt atgaaataaa tcaagttatg aaggatatag
     3601 ataaattggg attgaataca gtaaatgtac ctataattat aaatgtagag tccattaatt
     3661 ctgatattat gtcaatagat aataatagta aagaaaaggc aattaagtta ataaaaaaat
     3721 taaataaaaa aggtatttca acaatattag aggcatatcc atggattgaa aatggaaaat
     3781 tgtatgagac tgactggaac cctataaata aaaaaagatt tttttatact tggcaaaatg
     3841 ccatattaaa tgaacttata attgatgtag caaatccact ggatgtaaat gttttaaata
     3901 ttggttctaa ttttgtacat ttggaagaat atcaacaaaa ttggggtgaa ataatagatt
     3961 ttgtacaatc caaatttgac ggtcttgtaa cgtacagaac taattggtgg tatacaaaaa
     4021 aagatgattt aagtagtaag ttgttttatg aacaaaagtt gaacaataat ttttttgata
     4081 agttagattt tatatctata gcagcatatt ttgagttaag taataaacct gttaatacag
     4141 tggatgaatt aatttctgcc ttacactcat ctactgtaaa caatagagga caaaatataa
     4201 aacaagaaat atataacctt tataaagctc atagaaaacc tatatttttt ggagaattag
     4261 gtttttcaaa tagagaaagt gcaagttctc agccgtggaa tcatactcct tcaaaagctg
     4321 taaatggcga agaacaagca aggtgttttg aggcatataa gaaagttttt gaaaatgaag
     4381 actggataaa tggtttttct gtgttttgtg taggtaaaat agatgacgaa aaaaattttt
     4441 acccatcaaa agagagtata aaagttatta agtcttggta tgaataattt tgaaagtgta
     4501 gaatttatat agattaaata gatgattagg agagatataa atgaatgaca tcaaggttat
     4561 gactgtattt ggaactagac ctgaagctat caaagtagca cctttaataa aggaacttga
     4621 aaaaagagag aatataaaaa gtattgtttg cgttacagct caacatagag aaatgcttga
     4681 ccaagttata gaaaccttta atataaatgt agactatgat ttggatataa tggaaaaagg
     4741 acaaagcctg aatgatataa catgtaagat tttaaataaa cttccgttga ttttaaacaa
     4801 ggaaaatcca aatataatat tggtacatgg agatacaacc acaactctag ctacaagttt
     4861 gactgcattt tataataaaa ctcttgttgg tcatatagaa gctgggctta gaacctatga
     4921 taaatattct ccttttccag aggagttaaa tagacaactt acaggtatta ttgctgatat
     4981 gcactttgct cctactaatt tggctagaaa aaacttggtt tctgaaggaa aacctaataa
     5041 taatatattt gtaactggta atactgctat tgatgcttta aagatgacaa taaaagaaaa
     5101 ctataatcat cctataattg atgagattgg taacgatagg atgattttgt taacctctca
     5161 cagaagagaa aatttgggta aacctatgaa aaatatattc agagctataa agcgaatagt
     5221 agatgacttt gaagatgtac agatagtata tcccatacat ttaaatccta aaatacgaac
     5281 tatagctgat gagatatttg gaaaatttcc tgaaaaaatt catattatag agcctttaga
     5341 tgtagctgat tttcataact ttttaaataa atcttatatg ataatgactg atagtggagg
     5401 aatacaggaa gaagctccat cattaggtaa gccagttctt gtgttgcgtg ataaaacaga
     5461 aagaacagaa ggaattgaag caaagacact taaattagta ggtactaatg aagatagaat
     5521 atataattca gtgagcgatt tattaataaa taaagataac tatgttcaga tgagtaaagc
     5581 atctaatcca tatggagatg gaaatgcaag caaatatata gtggatataa taattaaaaa
     5641 atttaattgc aaatatttaa attagataag gcctaaaaca ttaactaatt gatataagat
     5701 ttatgataat attaaggaat acaattttta agggggagta atatggctag aaaattaata
     5761 aaaaatttgg gtaaaagtaa aagtgtaaag agagtgaaac ttttatttaa gaagattttt
     5821 attactgtat tcatagtagc aagtatagtt gctattttta atataacgaa atattttgag
     5881 gaattataca aagtaaggga tttaaaaagt actaaaattg aatactatat ggatgtggct
     5941 gatgaagcag gagatggaaa ggtccaatta agttggaagg ccttacttgc tatagacatg
     6001 gtaatacatg atgaagattt aagtaatata aaaaagaaag acacattgga tataggggaa
     6061 aagtttatag tagaagataa aaatggtaaa ggcgaaaagg tgtataaggt aaaaaagttt
     6121 aataaggtat taagcgaatt gaaatttgac tcttctcaaa aaagtagagc aagaaaatac
     6181 atgaaagatt tagaatacac ataccttgga aataaacaat tagatagtag tgatgaaaaa
     6241 attaaattta taaagaagtt agaagactca gctataagag aatatattga ttatggaata
     6301 ttgccctcta taacaattgg acaagctata ttagaatctg gttggggaaa ttctaaactt
     6361 acaaaacaga gtaataattt atttggtata aaagcagata aagcatggaa aggaaaaagt
     6421 gtagaaattt caacttcaga gcattataat gaaaaaattg tagctagttt taggtcgtat
     6481 aattcattac aagattctgt caaagatcac agtttatttt taattaataa taaaagatat
     6541 agaaaacatg ggttgtttga ggcaaaagat tatattagtc aagctcaagc attagaaaat
     6601 gcaggatata gtacagcaga agataaaaaa ggaaatcgta tatatgcaga gctattaata
     6661 gatgttatta ggagttataa tttgcaattg atagataata aagttgagac aaaataattg
     6721 ttaactttat atgaggagat aacaagataa gatttttttc tacaaaaaga atagaaaaat
     6781 tgtaaaaaaa actaaaaaaa tgtattgact tgttatttaa aaggtgatat tattattact
     6841 gtactcgaaa gagaacaaaa
//
LOCUS       DAEOTL010000142         6571 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEOTL010000142 DAEOTL010000000
VERSION     DAEOTL010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6571
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.144"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            477..1421
                     /locus_tag="KRH82_003715"
     CDS             477..1421
                     /locus_tag="KRH82_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBG8656963.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            1443..2069
                     /locus_tag="KRH82_003716"
     CDS             1443..2069
                     /locus_tag="KRH82_003716"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBG8656964.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            2103..3152
                     /gene="hisC"
                     /locus_tag="KRH82_003717"
     CDS             2103..3152
                     /gene="hisC"
                     /locus_tag="KRH82_003717"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBG8656965.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            3155..3733
                     /gene="hisB"
                     /locus_tag="KRH82_003718"
     CDS             3155..3733
                     /gene="hisB"
                     /locus_tag="KRH82_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBG8656966.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3735..4340
                     /gene="hisH"
                     /locus_tag="KRH82_003719"
     CDS             3735..4340
                     /gene="hisH"
                     /locus_tag="KRH82_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBG8656967.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            4337..5059
                     /gene="hisA"
                     /locus_tag="KRH82_003720"
     CDS             4337..5059
                     /gene="hisA"
                     /locus_tag="KRH82_003720"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBG8656968.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETALNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            5041..5799
                     /gene="hisF"
                     /locus_tag="KRH82_003721"
     CDS             5041..5799
                     /gene="hisF"
                     /locus_tag="KRH82_003721"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBG8656969.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5827..6495
                     /locus_tag="KRH82_003722"
     CDS             5827..6495
                     /locus_tag="KRH82_003722"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBG8656970.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
BASE COUNT         2685 a          553 c         1269 g         2064 t
ORIGIN      
        1 tttttttaaa ttattacaat ttttcccgaa atttcatttt ttatacataa aatttccaaa
       61 ttaggtaaag attaaatttt ttattgtata aacaaaagtt acatataaaa tattttattc
      121 aattttttaa ataactattg ccaatttttg aaaaatatat tattattaat agtaacaaaa
      181 aactgtaaat ttagaatatt aataaaaatt atttgggagg aaattatcat ggtgagatta
      241 aatatagtaa aattaaatac aaaattaaat catcaccatc atcatagatt aaagggattg
      301 taatatgaaa ttaattcata gacacaagcc ctgtttttag tgtaattggt cttgtatcta
      361 tgatgggaag taattttaag agaaaattat agccatatag gtataaagcc tatatggctt
      421 ttttattgtt ttaaatttgc aaatataaga gtaaatttaa tgaagagggt gagaatgtga
      481 aatttttgag gattgaagat gaggttattt attctaaaaa aagatataaa ttaaaaaggg
      541 aaatagataa actttttttg gatgaagaat attttcaaat agaaccacaa ttatttgaag
      601 aatatgatga atttacaact ataaataata aaattccaga agaatctatg gtaaaggttg
      661 taaatggaaa agtaatggta cttagagctg atataactac aagtataata aaaagccttg
      721 taccaagatg ggaagatggt ttaaagctta agctttttta taattcatca atatataaaa
      781 ataaaaatac agttggaata aaagagataa gacaaatagg ttgtgagtat ctaggagaag
      841 cctctgtaga agcagataga gaagtagtga aattagctct taagatactt gaaaaataca
      901 ataataattt tattctagag gttgggagta gcaagtatat tcatggtttg ttagaagaat
      961 taaatttaaa taagaattgt gaaaatcaaa ttaaaaattt actatatacg aagaacactc
     1021 atgaactaaa agtatatatt gaagaattaa aaattaagcg tgaagtaaaa gagttattat
     1081 caaatatttt aagtttacaa gggaatttat ataatgttat tgaaaaatca aacaagttct
     1141 attgtaataa taagatgaag caagctcttg aagaattaaa gcaagtaaat aatttaattg
     1201 aggaatgtaa ttttttagat aaggctagat ttgatttatc aatgattact atgcttgact
     1261 attatgaagg aattatgttt agaggatact acccaaactc atataaagaa attcttagtg
     1321 gcggaagata tgattcttta actaaagagt atggaaaaga aattccagcc attggattta
     1381 cactaagtgt tgatgagtta atgaagtatg tatataagta aagtttataa ggagggattg
     1441 ttttggatta tttgactata gcactagcaa aaggacgaat tgaaggggaa tcatttaaaa
     1501 aatttaaaaa aatgggtcta ggagatagta tagacacaga tacgagaaaa ctaattttta
     1561 aagatgaaga aaataaaatt atatatatac atgtaaagcc atcagatgta gttacatatg
     1621 ttgaaaaagg agtcgctgac ctcggtatag caggtaaaga tactatttta gaaaatgaga
     1681 cagatgtata tgaaatatat gatttaggtt ttggaaagtg taaatttgct gtagcaggat
     1741 taaagggaga tagcatatat agagaagatg aatatttaaa agtggcaaca aagtatccca
     1801 atatagcaaa aaagtatttt aaagagaaag gtcaaaaaat tgaaataata aaattaaatg
     1861 gttctgtaga actagctcca atagtagggt tgtcagatgt aattgtagat atagttgaga
     1921 ctggcaatac acttaaagca aatggtcttg aaatattaga agacatatgt aatataagtg
     1981 ctagaattat atcaaataga gctagctata gatttaaata tgaacaaatt cagaatataa
     2041 ttcgtttatt tgaagaactt gataattaaa atataattga gctttataag gagggattta
     2101 agttgagaga aaaagaaagc ataagagagt taaggggata tgaaccaaat cacgtaaact
     2161 gtaaagtaaa acttgatgca aatgaaggaa gtaagaggtt gtttaaatac cttattaaag
     2221 aaatttcaga tagtgatata gatttaaatt tatatcctga agattcttat agtgatttga
     2281 aagaatctat aatagattac ataaatattt ctggagtaaa taagaaaaat cttctagtag
     2341 gaaacggttc aagtgaaata attgatttaa taatacatac ttttgtagat aaagatgaag
     2401 taatattgag tttctctcca agttttagta tgtattctat atatagtcag ataaatgggt
     2461 ctaaatttat aggtgttgaa agtgatgaaa atttagttat aaatatagat aatgtgattg
     2521 aaaaagtaaa ggagaataat cctaaaatag taattgtatg taatcctaat aatccaacgg
     2581 gaacaatatt aaagagggaa gagataataa agcttttaga ttcaactaat agtctagtgg
     2641 ttttagatga agcatatatg gattttggag aagaaagcat gttaagtgat gtttttaagt
     2701 atgataatct aatagttctt agaactttat caaaggcatt tggattggct ggaataagaa
     2761 caggatatat gttatctaat agtagtttaa taaattctgt tgagaaagta agacctccat
     2821 ataatttaaa ttcattatca gactttattg ctacaagagc acttagaaat aaagatgtgg
     2881 taaaggctta tataaaggaa gtaaaagagg aaagagaagt tttatatgaa gaaatgattg
     2941 gtatgggaat taaagcatac aaatcacaag caaattttat attattttat tctgaaatcg
     3001 aaaatttatc acaaaaactt attgatagag gtgttttaat aagaaaattt ggtggaaagt
     3061 tagaaaatta ttacagagtt acaattggtg ataaagaaga aaattctatg tttgttggag
     3121 ctataagaga tattttgaaa aaggagaaat aggtatgaga atttggaagg tagaaagaaa
     3181 tactcttgaa acacagattt tagtagaatt aaatattgat ggttctggta aagctgaaat
     3241 agatactgga ataggatttt tagaccatat gcttacctta atgtcatttc atggcaagtt
     3301 cgatttaaaa gtgatttgta agggtgatac atatgtagat gaccaccata gtgtagaaga
     3361 tataggtata gctataggtg aagcatttaa aaatgcacta ggtgacaaaa aaggaatacg
     3421 aagatattct aatatctata tacctatgga tgaatctcta tcaatggtag caatagatat
     3481 aagcaataga ccttatcttg tatttaatgc taaatttgat acccaaatga ttggtagtat
     3541 gagtactcaa tgctttaaag aattttttag agcttttgta aatgaatcga gagtaacatt
     3601 acatatcaat ctcttatatg gggaaaatga ccatcataag atagaaagta tttttaaagc
     3661 atttgcaaga gctttaaaag agggtagtga aatagtttct aatgagatag catcttcaaa
     3721 gggggttttg tagaatgaat ataatagtag actatggtct tggaaatata gattctgtgt
     3781 ctaggggttt tagaaaagct ggaatagaaa ctaaaatttc tagtgatata gatgaaataa
     3841 aacaggcaga ttcacttata cttccaggtg ttggagcttt tagagattct ataagtgcct
     3901 tagataaact aggattgata ccaataataa aggagcatgt ttctaagggt aaatttatga
     3961 taggtatatg tctaggaatg caattacttt atgaaaaaag ttatgagtat ggagaatatg
     4021 aaggattagg acttataaaa ggaagtattg ataaactgga tataagttta aaagtgccac
     4081 atatgggatg gaataatcta aaatttaata aggcaaatga tgatatactt aaatatataa
     4141 atgaagatga ttatgtatac ttcgttcact catattatgc aaattcatca aatgaagaac
     4201 taattgcatt ttcagaatat gaaaagaaaa tccctgctat tgttagaaaa ggcaatgtat
     4261 atggtataca atttcatcct gaaaaaagtg gagaagtagg gttaaatata ttaagagcat
     4321 atggggagat gataaaatga taatatttcc agcaatagat ataaaagata ataagtgtgt
     4381 aagactcaca caaggagaat ttgacaaagt aaatgtatat tatgataatc cattagaagt
     4441 agcatataaa tggaaaaatg aaggagcaga atatatacat atagtagatt taaatggtgc
     4501 tagaagtgaa tttggtgtaa atacaaaaat aattgaggac atagcaaaca atatagatat
     4561 acctattcaa gttggcggtg gagttaggga taaggaaaaa gtcaaaagtt taataaatgc
     4621 tggtgttact agagtaatat taggcagtat agcgattgaa aatttgaatt tagttgaaga
     4681 attggtcaat gaatataaag agaaaattgt agtttctata gatgctaaag atggaaaagt
     4741 agcagttagg ggatgggaag ttgtaagcaa tgtagactca ttaacattat gtaaacaact
     4801 tgaaaagata ggtgtacaaa ctattgttta tacagatata tcaaaagatg ggatgttgca
     4861 aggtccaaat tttgacatat atgaaagaat agcaaaggaa acagcactaa atgttattgc
     4921 ttctggaggt gtaacttcta tagaagacgt aaaaagacta aaagctatga acttatatgg
     4981 tgcaataata ggtaaagcgc tttatgataa aaagatagac tttaaggagg cacaacaatt
     5041 atgcttacta ggagaataat accttgtcta gatgtgagaa atggaagagt tgtaaagggg
     5101 aaaaaattta aagatatagt agatgttgat agtccagaag tacttggaaa attttatagt
     5161 gattgtggtg cagatgaact tgtattctat gatataactg catcaaatga agagagaaag
     5221 acatctttag aatttgtgac aaaagttgca gaaaatataa atataccatt ttgtgttggt
     5281 ggaggagtaa ataaattaga agatttcact gatattttaa gaaaaggtgc tgataaagtt
     5341 tctataaatt catcagcagt caaaaatcct gaattaataa gggaagcttc attaaaattt
     5401 ggagcacaat gtgttgtttt atcgatagat gcaaagaaaa atgaagaggg ttcatggagc
     5461 gtatacgtaa aaggtggaag agaaaaaact aatctggatg caattgaatg ggctgttaaa
     5521 ggtgtagaac ttggagcagg agaaatcgtt gtaaatagta tggatgaaga tggaatgaaa
     5581 aatggatatg atatagaatt attatcaaag ataacttctt tagtaaatgt acctgtcata
     5641 gcatctggag gcgctggaaa aaaggaagat ttttatgagg cggttaataa atccaatgta
     5701 gatggaattt tagcagcatc tgtttttcat tttggcgaga taaaaataaa cgatttaaag
     5761 aaatatttaa aagacatggg tgtagaagta agattataag ttaaatacta aaaggagatt
     5821 agaaatatgg ataataagtg taacaatgta tacagtgatg aagtagagaa atttataaga
     5881 agtataaagt ttgatgataa agggttagtc cctgttgttg ttcaagaggt agttagcaaa
     5941 gatgtactga tgttagcata tatgaataaa gatgctataa agaaaacctt aaaagataaa
     6001 gtagcttgct attttagtag aagtagacaa gaactttggg ttaaaggtga gacatctggt
     6061 aatactcaaa aagtagttaa gatgtcttat gattgtgatg tagatactat actacttttt
     6121 gttgaacaaa ctggtgtagc ttgtcataca ggcaattatt cttgttttta cagagacttg
     6181 tttgatgata gttcaaaaat ggagcttgaa gtacaaacaa atatattgaa agaattatat
     6241 gatttaatca atgaaagaaa aaataatcca gttgaaggtt cttatactaa ttatcttttt
     6301 gaaaaaggaa tagataagat tcttaaaaaa gtaggtgaag agagtagtga ggtaattata
     6361 gcatcaaaaa atactgataa aagtgaactt atttacgaaa ttagcgattt agtatatcat
     6421 acattggttt taatgataga aaaaggtgtt gaaattgatg aaataaaaaa agaattactt
     6481 aaaagaagaa aatagaataa gatagattaa tgggtaataa gaaaatatac cacttttaat
     6541 aaaaagtggt atatttttta ttttatattt t
//
LOCUS       DAEOTL010000143         6144 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEOTL010000143 DAEOTL010000000
VERSION     DAEOTL010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6144
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.145"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(113..520)
                     /locus_tag="KRH82_003723"
     CDS             complement(113..520)
                     /locus_tag="KRH82_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656971.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(994..1878)
                     /locus_tag="KRH82_003724"
     CDS             complement(994..1878)
                     /locus_tag="KRH82_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8656972.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2169..2645)
                     /locus_tag="KRH82_003725"
     CDS             complement(2169..2645)
                     /locus_tag="KRH82_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBG8656973.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDENCGCGCNHHHEN"
     gene            2912..4087
                     /locus_tag="KRH82_003726"
     CDS             2912..4087
                     /locus_tag="KRH82_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBG8656974.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4168..4971)
                     /gene="proC"
                     /locus_tag="KRH82_003727"
     CDS             complement(4168..4971)
                     /gene="proC"
                     /locus_tag="KRH82_003727"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBG8656975.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5011..5595)
                     /locus_tag="KRH82_003728"
     CDS             complement(5011..5595)
                     /locus_tag="KRH82_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8656976.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2047 a         1037 c          684 g         2376 t
ORIGIN      
        1 ccagcaattc aagtagtatt ggataggttc tatcctatct ctacatatag gtttccctat
       61 atgctgacta ttttagctac taactcatga ctaaagtcac gagtgtgcgt agctattttt
      121 taatcaatat tttagtaaat tttacggtaa gtaaaaacct ctctccttca aatcctatag
      181 caaatatact tacaagttgc tttgagaaaa taactcctaa tatagctaca actatgcata
      241 taccaactat tatatttaaa acattgttta aaaactttag tgcttgcttt tcaccttgtt
      301 tactacttat atcttgatac attggaataa aagtagtaac tatagcagta cctattgctg
      361 caaatataat atttggtata ttcatagctg ttaaataact ctctgtatat aagcctgtac
      421 cataaattga tgataatact aattctctac ccattccaag aatcttagag attatagtaa
      481 ctatcatcaa ataaaaagtt gctttagcta ccttgctcat tttatcactc cacttctaac
      541 atacctcttt ttaatcaagt aaaatttagc tcattagata taattctatc aactaatttg
      601 ccttgcttag ccctatcaaa atataattaa cacctatttc ttaatatatc acaaactaca
      661 ttattcttca tattttttta tttctccaat aagttttaca tttttcctat ataaattgta
      721 tagcttcaat tatattcaaa gaaatggagt tgctacccga taactttaaa agtaaaaaac
      781 agattttatt atctttttaa actatattct aacatatttt gtccatattg agaaatttta
      841 ctaaactatt atgtacttta ttaaataaat aaaataacag cacacctata aaatacaagt
      901 gtgctgttca taaacagatt ttataaaaaa ataattccta agtagagatt aacatgcttt
      961 ctcatactct catatataat gtgtctaaaa atattaataa aaatgcttta attgttttaa
     1021 cttacttgga tgtcttaatt ttcttattgc tttagcttct atctgtctta ttcgttctct
     1081 ggtaactcca aatacctttc caatctgttc tagtgtttta gggtcatcat catcaattcc
     1141 aaatctcatt cttaaaactt gctgttcttg ctctccaaga cctgtaagta gttcttctat
     1201 cttttctttt aaattatgct gttcaacttc gtgtattaca acatctttaa aatcagcatc
     1261 tgatggtata aattcaacta aactactatc ctcatcttct tttaatggag tatccaaaga
     1321 tacaacattt ttatctcttc ttaataattc caacactttg tcaacttcta agccacatgc
     1381 atctgcaatc tcatctatag ttggctctct taataacaca tttaaaagtt cttgtttctt
     1441 tttctttaca aaatttattc tctgatgaag atgtataggt atcctaatag tattttcgca
     1501 atcgtcgata tatcttgtta tactttgttt tatccaccaa gttgcataag tgctaaattt
     1561 gtatcctttt ttataatcgt acttttctac agcttttata agtcctatat ttcctgcttg
     1621 aattaaatcc aacatatcaa tactatctct tttatatctc tttgctatgc tcactaccaa
     1681 cctataattt gaatttataa atttttcttt tgctactgaa gatgagttga ttatttcctt
     1741 agccagctct acctcttctc ctgctgacaa cattttgtat tcctctattt cctttaaata
     1801 cattttcatc gcatttgata catttgatga acccacacaa atataatttt cataattatt
     1861 ttctttttta gtatccataa tcaaacccct tctattcata gaatttgcta aaacaaaaat
     1921 aaataattta aacctacata atctacaatt acataatatc ccattcttta aatgaattgt
     1981 tttgtatatt atgtatacaa atttataaaa actataccta taatattatt ctacttctaa
     2041 cagcaatatc ctccttatat atataattta ttttattata tgttgttata ttcttagttt
     2101 tttgaatgat atatgtctaa aaaaagactg tttactaaac agtctttttt tatatatatg
     2161 ctcaatattt aattttcatg atgatgatta catccacatc cacaattttc atcatggtga
     2221 tgatgttctt ctaaatcttt tgcctgttgt tccatttcat gaaactcttt taccattata
     2281 tcataagttg gaagagctgc ctcagtatcg tattcttccc ctctccaatc agcgtacatc
     2341 atagcatctc cattagttaa aaccaatcta cctgacatag ttatattatc cacttcttct
     2401 aaaaattcta tttgtttttg taaaacttct ccttctaact ccacatcttc atctaaacat
     2461 tgcactatca ttacaggtgc ataataatct tcttcatctt taacatttac aacaatatct
     2521 aaaattcctt ctgcaccttc ttcaaattct gccaactcaa catttgtatc aatcatatct
     2581 tgaggtacta ataaatcttc tattaaatat tttattactc tatcttttac taattctttt
     2641 gacatttatt tttctccttc cgattctata acattatcat aatcatttct atattatagt
     2701 atactacatt aattgttttt tcaatctctt acaaaaatta tttttttatt atcttcctta
     2761 tattcccttt tttattacaa agttgtaatc gcattgattt aaaaaatagt ttatatttag
     2821 tataatagaa atgtagcaca tatttttatt caatatatta ataaaaaaat agattgaaaa
     2881 tgtaatgtat gttaaatcta ggaggaatat tatgaagttt aaaaaacaaa ttagttctat
     2941 tgttgtgtct actatgcttg tacttgggag tatgaacctt tcttatgcag acggtacaaa
     3001 tgtagttaca cttggagcta acttatcaga gtctcaaaag cagcaaatgc ttaattactt
     3061 tggagtaaaa aaagaccaag tcttagtttt agatgtaaca aatgcagaag aaagacagta
     3121 tttacaaggt gttgcaacag agggtcaact tggaaaagtt actatctctt gctcatacgt
     3181 tgaacctact aaaaaaggaa atggaattaa tgttaaaaca gcaaacttaa cttgggtaac
     3241 tagttcaatg attgcttcaa cccttacaac agctggtctt gaagatgcaa atgttattgc
     3301 tgctgctcca tatcctgtaa gtggtactgg agcattgaca ggaatcatga aagcatttga
     3361 ggatgcttca ggaaagaaac ttgatgaaac taagaaagaa attgcttctg aagaattggt
     3421 agttacaggt gacttaggag atgatatagg gcaagaaaaa gcaacaggtg taatgaatga
     3481 tataaaaaca gaaattgtaa agaatggtac aaaagatacc aatcaaatag caaatacaat
     3541 aaataatgtt gtaaataatt acaatattac tattacacca gaacaaaaag aacaaattaa
     3601 aggtgtaatg aaaaaaatag ctgaccaaaa ttacgattac aatagcatga aaaatacact
     3661 agataatgta tcagataatg taaatgaaca attaaagaaa ttaggtgaaa gtgttaaggg
     3721 ttctggtata ctagatacta ttggtggatg gtttagtgga ataggagact ggttctctgg
     3781 tttattctca ggcggagata aaaaagattt gggaatctta aataacacta atgatgagtc
     3841 tcttggctct gatgctgtaa taaattctac agaaggtgtt caaataaatc cacaaaataa
     3901 tactaattct aacaatgata gtgatacaaa tagctcaaaa aatgatactt caagtaataa
     3961 tgaaaataac gatagttctc aaacaaatga aaacaacaca acaaataatt cagaaaatca
     4021 atcaaataat aatgactcag ttggtttctt tgaaaaaata aaaaattggc tttcaggctt
     4081 attttagaaa ttaaacaaat aaaaagaatt gcctaaaatg gaaattttct ataaaaggca
     4141 attctcttta tttacaataa atttttatta ctcactcatt tttttagatt tttctataca
     4201 tgcacatatt gcttttatca cagaagctct aaaaccttct tcttcaagta ctttaactgc
     4261 ttctatagta gttccaccag gtgaacatac catatctttt aattcaccag gatgttttcc
     4321 tgtctcaagt accatttttg cagaacccat aacagcctgt gatgcaaact tatatgcttg
     4381 tggtcttggc attcctgcaa ttactgctgc atctgctata gcttctataa ataaaaatac
     4441 atatgctggt gcagaaccac ttgcaccaat tacagcttct ataagatact ctggtactac
     4501 ctcagtattt ccaaaagaat taaatacttc tgtaactgct tctaagtctt ctttgtttat
     4561 atttttattt atagaaagag aagacatggc ttcatttaca agagctggag tatttggcat
     4621 agttctaact atttttttat cttctcctat aatagactct atatctttta tagattttcc
     4681 tgctgctatt gtaactataa ttttattgtc atctataaag tcttttatct cttccaaaat
     4741 atcatcatat atatctggtt taacagctac aattactata tcagaggttc tagttacttc
     4801 cttcgagtct tttgtagtat ttattccaaa atttgcatct attctatcga gagttccttg
     4861 actatatgct gatgctataa ccatattagg ttcaactaat tttgaattta ctattccccc
     4921 tatcatagcg cttgccatat ttcctgcacc tatgaatcca atttttttca ctttagtacc
     4981 tccttattga ctaatagtaa tcgttaaaat ttaagcttct ttaactgcat cagacttttc
     5041 aaatggattt ggtatactta ctaccaaaat tttcactacc ttattagtat agttgaccca
     5101 attatgattg ttcttttcac tattatagtg tattgtgtct cctggataca tttctatttg
     5161 ttcatctccc aaaaacactg taagagtacc ctctaataca tacacaaact cctcaccttc
     5221 atgtacgtaa caacaaattt cctcactact cttacttgga agaatttcaa ttaatcttgg
     5281 tagcattgtt ttttccttta aactagatga taaatgataa tgtataaatg ttgagttttc
     5341 tacatcaaat acttcttttt cataacttct taatacagct cttttatgct cttttggctt
     5401 cataaaaaag taagttaatt ctacatctag tacacttgct atttttccta aggaatctgt
     5461 tgccacactt gttaatcctc tttcaagttg tgataaaaaa ccaattgaca agtttgtttt
     5521 ttcactcata tccttcaacg tcatttgctt ttgagttctg agttgcttta tttttgctcc
     5581 tatgtcctta ttcaaaacca tcacccctaa ataattttaa ttttttcata atataaatac
     5641 aaaaatataa atataggtac tgaacctatc tttatttcat ttaaaaaaat ttttataagt
     5701 attactataa tttatcaatc tttttttgtc tacattttta cgattattta cgatttattt
     5761 ttcacatatg tatatttaat cttgccaact aaatatacat tttttataag catttactct
     5821 ttatataata aaacttaagt tgttcatgta gtcttcttct ggtttaatta ttaaaatttc
     5881 aaattatatt attatttcta cacattatta catcctttag tacaattata acataatttt
     5941 acaatttaat gatatctatt caatgtcttt ttttactcta caacatattt tattttagag
     6001 tttaatacta tatatatttt ttatatacag ccttgtcatt ttttagattg tcaagagtta
     6061 ttgaagtatt ttatgtagat ttagatttta tttcctaatt tctcatttaa caagaattgc
     6121 ttatgataaa aaataatatc atct
//
LOCUS       DAEOTL010000144         6139 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEOTL010000144 DAEOTL010000000
VERSION     DAEOTL010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.146"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            215..1027
                     /locus_tag="KRH82_003729"
     CDS             215..1027
                     /locus_tag="KRH82_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBG8656977.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(1116..1307)
                     /locus_tag="KRH82_003730"
     CDS             complement(1116..1307)
                     /locus_tag="KRH82_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656978.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            1610..1816
                     /locus_tag="KRH82_003731"
     CDS             1610..1816
                     /locus_tag="KRH82_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8656979.1"
                     /translation="MFKKKSGYTFTNFLSKVRVEKSKKYILKKDLSTLDVAVLIGFNS
                     QNYYSIIFKKFNNFTPIEYKNIYN"
     gene            2125..3744
                     /locus_tag="KRH82_003732"
     CDS             2125..3744
                     /locus_tag="KRH82_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBG8656980.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            4118..4312
                     /locus_tag="KRH82_003733"
     CDS             4118..4312
                     /locus_tag="KRH82_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8656981.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(4871..5194)
                     /locus_tag="KRH82_003734"
     CDS             complement(4871..5194)
                     /locus_tag="KRH82_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656982.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(5239..5493)
                     /locus_tag="KRH82_003735"
     CDS             complement(5239..5493)
                     /locus_tag="KRH82_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656983.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(5757..6038)
                     /locus_tag="KRH82_003736"
     CDS             complement(5757..6038)
                     /locus_tag="KRH82_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656984.1"
                     /translation="MASKQTPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDIVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT         2261 a          769 c          744 g         2365 t
ORIGIN      
        1 tatatgacta agttctataa ctaaattgaa ataatcactt tttcaagaat gttataattt
       61 ttttattgta ttctttttgc tatagtctat gaataaatca atagaaaatc ttctaagttg
      121 cttttaaata atgactttat ggttcaattg tactaaaata gtatatgtag gttacaaata
      181 atctaataaa tattaaagtt tggaggtaat agatatggca gattgtaatt catgtccatc
      241 aaagggaaat tgtaatagtc aatcaaattg ttctattgaa aataacccta acaataaatt
      301 tggaaaaata attggtgtta tgagtgggaa gggtggagtt ggaaaatcaa ctgtaactgc
      361 tttacttgct aataagctaa acaaaatggg atataaggtt ggtatattag actcagatat
      421 aactggacca agtattccta gacttatggg tgtaaaaaat gtaaaagctt attctgatgg
      481 ctcttatatt taccctgtag aaaactcaaa taacataaaa gtaatgtcta taaaccttat
      541 gatagatgat gaaaatgaac ctgttgtttg gagaggacct ttacttggag gggttgtaaa
      601 gcaattttat actgatgtac tttgggaaga attagactat ttattaatag atatgcctcc
      661 tggtactgga gatgttgcct taacagttat gcaatctatt cctataagtg gaatagttat
      721 ggtttcagta cctcaagatt tggtatctat gattgtatca aaagctgtta atatggctaa
      781 aaaaatgaac ataaatgtcc ttggagttat tgaaaatatg agttatatcc aatgtcctga
      841 ttgttctaaa aaaatcaagt tatttgaagg agaatctact gaaaagtttt tagatgattt
      901 agacttagaa cttttaggag aacttcctat gactaaagaa attatagata ttactcataa
      961 tggagttaca gaaattagtg atgatttaga ttcaatattg actaatgttg ttgaaaaaat
     1021 taaataaata aaaattttat aattttatat ttatcaaaaa aagaggcttg tatttatttt
     1081 ataatcatac aaataaatat aaacctcttt tatgtttatc tatgttttaa atacacaaaa
     1141 tattcttcta cttcatctcc attttttact tttactaaat attcattata atgagcatta
     1201 tatggctgtg tcattttgca ttctattaca ttttctatgt cttctaattc taaaagttct
     1261 acatccttta aaaattttct ttctatgagt tccattaatc tttccataat atatcctcac
     1321 ttcccctata attaagataa actatatatc ctcttaatac agagtttatc ttaattatat
     1381 tatatccaat atattacagt ttctaacatc attcataaat tattttaaca aatagagatt
     1441 gattttttaa taaatatgcc ttgataaaat gaaacataga ccaactctta gttttatgta
     1501 aagaaaactt aaagaaaact atagattata ttcacaaaaa ttactcagaa gatataacag
     1561 taagtaatat atgtaatgaa ttacaactta ataaaagttg tttttttctt tgtttaagaa
     1621 aaaaagtgga tatactttta ctaatttttt aagtaaagtt agagttgaaa aaagcaaaaa
     1681 gtatatatta aaaaaagact tgtctacttt agacgttgct gtactaattg gattcaatag
     1741 tcaaaattac tatagtataa tttttaaaaa gtttaataac tttacaccaa ttgaatataa
     1801 aaatatttat aactaaaaaa tatcattcta aaaagatgtt atttttttac atatttttta
     1861 caattatagt taattctttg ttaaattgat tgtacataaa atactaaaaa tctaagttca
     1921 agtatttaaa ttgctatata tcataaattt tctaaaatta acaacaactt aaaaatttaa
     1981 cattctctta acgtatactt aacaaaacat taatattttt attgacaaaa tttgttattc
     2041 tatattatgg aaacaataaa ttttagttaa taaagtttat aattcagata aaaaaattat
     2101 taatttctta agggaggaaa tatcgtgaat atagtaatta gccttatcgg tggacttgga
     2161 ctttttcttt acggaatgag tttaatggga gaaggtttac aaaaatcagc aggagacaaa
     2221 ttaaaaaaaa ttattgaact cttaacaagt aatgttgtta tgggtgtact ggtgggtaca
     2281 gtcgttacag gtattataca aagttcaagt gctactactg ttatggttgt aggatttgta
     2341 aatgcaggta taatgaatct aagtcaagct attggtgtaa taatgggggc aaatataggt
     2401 actacagtta ctgctcaatt agtttcattt aatcttgaag gaattgcacc aattgcttta
     2461 ggtataggta ttttattcta tttatttaca tcaaatcaaa aaacaaagca tttatctgag
     2521 atacttatag gtttcggtat attatttaca ggaatggagt ttatgaaaga tgcagtagct
     2581 ccacttgctg aatacaaagc attcactgat gcacttttat attttagtaa aaatcctgta
     2641 ttaggtatat tggcaggatt tgccataact ggtattgttc aaagttcaag tgcatctatg
     2701 ggtatgttaa tagcactagc ttctcaagga atacttcctc tatcatctgc tttacctatt
     2761 ctttatggag ataatatagg tacttgtgtt acttcacttt tatcaagtgt tggtgcaagt
     2821 agaaatgctc gacgtgcagc tgtaatgcat ttaagtttta atgtaattgg tacaataata
     2881 tttatgcttg ttttaaataa acctatatca gccatagtta ctcattttga cccaactgat
     2941 acagctagac aaatagcaaa tgcacatact ttatttaatc ttacaaatgt tataatatta
     3001 ttaccatttt ctaaatacat agttaaatta gcaaatagac ttatacctat taaagaaact
     3061 gaatcagaaa tagtaaataa tactaagtac ttagatgaaa ggatgtttag cactccatct
     3121 atagcacttg gtaatactgt acaagaagtt gtaagaatgg gtcataaagc tacaaactct
     3181 ttggaacatt caattgcagg atttttaaat aagagcaatg aagatattaa taaagctttt
     3241 gagtcagaaa aagttgtcaa taagttacag aaagatatat tgaactattt gttaaaactt
     3301 tctaaagaac ctcttagaga tgatgaacgc tttagaacag atttgctttt taatactgta
     3361 aatgacattg aaagagtctc tgaccatgca gaaaatatag ctgaattggc catgagtgtt
     3421 aaggaaatga acattagttt ttctgatagt gcgataagag aaatatacga aatatacaat
     3481 aagacaatta ctaattttaa ggatgcctta atagttttag atgttaaaga ttttgagtta
     3541 gcaaataaag ttttagaagt tgaaaatgaa gtaaattatt tagaaaaaac ttttagaaat
     3601 tcacatatga ttagactaaa taatggaagt tgtacaattg atgctggtgt actttatctt
     3661 gacttactta ctaatctaga aagaatttct gaccactcaa caaatatagt aaaacaagta
     3721 ctaaaactta aacaaaaaat atagtgatta tttttatata taatcttaat caatgagaag
     3781 taagaagcta tagataatgc ttatatcatt tatggcttct tattttttat gtaatactca
     3841 aatttttata gtattctctt attattaaac agtttctgcc tagaatattc catatatata
     3901 tgacttcttt cataaaactt gaactgccca taaataaagt cacaagtata cataactatt
     3961 ttttaatcaa ttataaccaa tatttgtttt atttatcttc attttaattc ttcattcaat
     4021 aatgtaataa gattattttt tatttggata ctattatatc atctaaatat gttattatat
     4081 atttggatat tttcatatta ataggaggga ttctacaatg ataaattata tggtagaaat
     4141 tatatatagc gaaaaaataa gcgaagtaga aaacatgttg aaaattgaaa atatacaata
     4201 tgaatttact tctcgtgatg gctttatatt ttttggtttt tatgatatga cagacgcata
     4261 tagatttgag actttatgtt cagatgaaaa aattcgattt aaaagaatat aatagataaa
     4321 aaagtacata tttctaaact atttgttttt caaatttagg ttgtgtttta atgtagtgtt
     4381 gatattataa acaattttaa taataaaaaa gtagggacat tatattaata tgctcctact
     4441 ttttactcat acttattaat attatttatc aaaattaccc tacaaactgg aatttatcat
     4501 tctttcataa ttttaaacta tcatatttaa aatatataaa attctacatg atttttgtat
     4561 aaacataata tcaaccatta tccaatttaa aaatattttt tagtaatttc catttcattt
     4621 tctcttaaca tattaattaa acttttatat gtaaatggtg tatttacata ttatttaata
     4681 tccaacaatt atataaagaa atgtgctctt tgccttataa agaattataa agccaattcg
     4741 ttttattata ttatttttct ttatacctta aaaactttac cttcaaattc ttatttatct
     4801 atatattata aaaatgttct taacctcttt tacgagattt tcttgacata ttatcagtta
     4861 gataaaataa ttaaataata taatcagcaa gtatgttttt tactctttta agtaaatttc
     4921 cacctgcacc ccaatcaatt tttaaaattc caattgcact gcctgttgaa gtagctttaa
     4981 taactgtttt tcctgtggta ttttcataaa ctactattaa tcctgcatca ctattatttc
     5041 ttgcataata cttctcaaaa gttgtaatta gtataaattt atcatctcct aaattataag
     5101 aatcactaaa aactaaatct gcatcaagat tttcttttat cattttttgt gcctctaagg
     5161 gtgtaatttt tacagtaaat atttctgttg ccatttttta tctcctcata agaatttatt
     5221 ttagacaaaa cataatctct agtattttct gatatattta tcaaacaata tccctattcc
     5281 tcctaacaga gctaatatag aaccaaaatt tctatattga gaaatagatt ggtctagata
     5341 aatattatat tggtcagtat ccatgattcc accattttgt tgaataatat gctctgcact
     5401 aaattcacct aaacctatac aacagaataa tactactact ccaattacaa aagcaaatat
     5461 acatattgtt aatttaaaat ccttattttc catagttatc cctctcataa gctaaattta
     5521 tttgattatt tttactagat tttatattac tcttattata caatacaaca tatatttaca
     5581 tctatttcca aaattgtaac ctttatagtt ttatatattt aaatttttta aacaaaaaat
     5641 acacatctat aaattataaa tgtgtattct gtaccattac taataatata ttatactttt
     5701 ttacaaattt ctaattattt ataactattc aaaaataaaa ttcatataaa ataattctat
     5761 tgtacaattg aaactttaat aatgtctcca ttttttctct ccaagtgaac tacttctcca
     5821 gttaaatcat agtcaaatgc tttaactaat atttcagtaa cttttttacc atctactata
     5881 tcatcttttc cattaaataa atccaaagca ttattctcaa tcattctctt tgcaaaattt
     5941 acaggtaact ttatatgtat tttatcgcct gtatgtgata agactcttat tcttaaaaac
     6001 ttttctaaat tgtttcttgg tgtttgtttt gatgccatgc tattaaatca ctctccttta
     6061 ttttttattt aataataaat tttattctta aaaatatctt tatatgtatt tattatgaaa
     6121 gtaacactat tattttcta
//
LOCUS       DAEOTL010000145         6087 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEOTL010000145 DAEOTL010000000
VERSION     DAEOTL010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6087
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.147"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            146..1327
                     /locus_tag="KRH82_003737"
     CDS             146..1327
                     /locus_tag="KRH82_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBG8656985.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(1469..2386)
                     /locus_tag="KRH82_003738"
     CDS             complement(1469..2386)
                     /locus_tag="KRH82_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8656986.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            2639..3433
                     /locus_tag="KRH82_003739"
     CDS             2639..3433
                     /locus_tag="KRH82_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656987.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIELARKEDI"
     gene            3434..5494
                     /locus_tag="KRH82_003740"
     CDS             3434..5494
                     /locus_tag="KRH82_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBG8656988.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLILLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSILLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         2371 a          665 c          962 g         2089 t
ORIGIN      
        1 gtttttgtgt ataattataa caatttaatt tatattaatg cacttaaatt tgaaatagaa
       61 tgcttatagt ggtaaaatta attattagaa tattagaaat aataaataaa taatacattg
      121 tacttaaaag ggggagaaat ttaagatgaa caaaaaatat attaaagcag ggaatttaat
      181 tgatggaacc ggaaatagta ttatgcaaaa taagggtata attattgatg gagatactat
      241 agttgaaatt gaagatataa gagatgattt aaatggatat gatgtgtacg attacttaga
      301 taaaactgtt atgccaggca ttatgaattg tcatgttcac ttgacaatgg agccagttgg
      361 aaatccaaag atatattatg ataatgtatc agatgtagag cttgtagtaa atacgataaa
      421 acaacttgat gcttatttgg attcaggagt aacatatatt agaagcttag gttgtcccaa
      481 atatgtggat gtacaactta aaaatcttat agacaaaggg tctatagatg gtcctggtat
      541 agttacttca ggtccagtta tatgtatgac aggagggcat ggatattatt ttggtattga
      601 aagtgatgga gtggatgaat gtagaaaatc agccagaaca gttttaaaaa atggagtaga
      661 ttgtgtaaag ataatggcaa ctggaggtgt aacaactgat ggagttgagc cagggtcacc
      721 acaattaact ttggaggaaa tgaaggctgc tgtagatgaa gctataaaag caggtaaaat
      781 aactgccaca catgcacaag gaagaactgg tataaaaaat gcagtgcttg caggaattac
      841 ttctatagaa catggtgttt atttagatga tgaaataatt gatttgatgc ttgaaagagg
      901 aacttactta gttccaactg tggctgcacc atattttatt ctaaatgcag gaaaagaaag
      961 tggaataact gaagctactc ttagaaagtg tgagattgtt gccattccac acaaagagtc
     1021 attcctaaaa gcatataaaa aaggaattaa aattgcagtt ggttctgatg caggaacttc
     1081 ttataatgaa catggaaaaa catattatga aatgaaacta atgtcagatt atggtatgga
     1141 taatatggat ataatagttg ctgctacaaa aacagcatct gaacttttaa gaattgataa
     1201 aaattatgga actctagaaa aaggaaagaa agcagatgtt atagttgtaa atggaaatcc
     1261 agtagagaat atagacgtac ttgcagatgt gttagcagta tttaaacttg gtaaaaaagt
     1321 tagataaata gtataaaaat aaaaaagagt gtctaaagaa atttttaaat aattatagac
     1381 actctttttt attagtaata attaaatctt ttatacttta gaaaatagat tctattttat
     1441 atttagatat aactctttaa aatcattctt atgcaatata atctatagaa tctacacata
     1501 caaagtatat tcttgaatca ttagaatttc caagtactat aacatcattt ttcttaccta
     1561 gaacttcaac accagttaga accaaactac cagctactac agtaacttga ttatttatat
     1621 ttgacatata aagattatct aggatacctt tattacaaca gcaatcatca caatcgcagt
     1681 tacaattaca ttctttgtaa tgttttttat caagatagta acctaaagat gctatgaaat
     1741 cttcataatc tgcaggtgta atatcaaatg caacagcttt aagattacac aatgatgcta
     1801 aatctacgtt tgctaatgga gtagatgcag caagtataaa atcaattata gcagcaagta
     1861 ttgcatctaa tatagcccca aggtctatcg taggaggaat aactgcatca ataagtgcaa
     1921 ttaattcagc tactcctggt atagttccta tagtattaat taatccctca agagttaaag
     1981 ggactggaat aggataagat actctaccag ctatatctat taaatcacag ttacaagcag
     2041 aaaatctttc aaaagtacca tcaagtccag ataaattatc ttttggagga gctgaaagat
     2101 ctatacctac caaattagca cctactataa agaaatctga gataaaagca aattgattaa
     2161 agtttacaaa aggtcttaga gcatcatatc ttagaagttc taaggcctct ctcatacttt
     2221 ttttacaaca acattgtttt attttaggtt ctttatattt atttggataa ttatagtatc
     2281 tatcagctac ttgataattt tcatagtatc tttcatttgt atttggataa tcttcctcat
     2341 attcttgtgt aaatctaaag tcctctctac atttattatt ttccactaaa tacactcctt
     2401 ttatatttta atttaaatgt atagataatt aagcttatct atatagtaat attatattta
     2461 taatgtaaaa aaatgttaca aaagatatta taaacaaata aaaaataata atttgtcaga
     2521 taaacttgta aatttttatg aataatccat tctaaaacaa aaaactgtgt ataaaaaagg
     2581 tttatatgtt atatttatat aaatataaca tatgaacgag aaaggagtgg tttgataaat
     2641 gattgaggta gataaattgt gtaagtcttt tacaagggtt gtaaaagatg ataagaataa
     2701 aagttcaata agaaagctaa agaaagtaaa aactaaaaaa gaagaatttt ttgctgtaaa
     2761 taatgtttca tttaaagtta tggaaggtga aattgttgga atattaggtc caaatggtgc
     2821 aggaaagact acattactta gaatgttagg tggcatatta acaccaacat caggaagtat
     2881 aaatatttct ggatatgatt attcaataga tagaaattca gcaaaaaaag aaataggtta
     2941 tctctctgga aatacaaaac tatatggaag gctttctccg agagaacttc taacaacttt
     3001 tgcaagtcta tatgagatgt caaaagaaga tatagaagaa tcaattgaaa atattgtaaa
     3061 aataatggat atgagtgaat ttatagataa tagaattgaa aatctatcaa ctggtcagac
     3121 tcaaagaaca tctatagctc gttgtttaat acattctcca aaagtatata tttttgatga
     3181 gccaacacta ggtctggatg ttttaagtag tgcatctatt atagatttta tgaagaatga
     3241 aaaactaagg ggaaaaactg ttctttactc aactcattat atggaagaag cagaaacttt
     3301 atgtgacaag atttttatga ttcacaatgg gaaaataatt gcatcaggaa caccacagag
     3361 tttaaaagag gaatctggag taaataattt gagagatgta ttcatagaac ttgccagaaa
     3421 ggaggacatt taaatgagaa gtaagattgt aaaatacata tttaaaaaag aaatgttaga
     3481 catattgaga gataaaaaga ctttatttat gatgattgtt gtgccacttc ttttatatcc
     3541 tttacttatg ttattaatga ttcaagtaat gaatatgtct gcaagtagta tgaatagtaa
     3601 ggacattaat atagctttta ataataaacc taataaggtt ttagtatcca tgattgaaga
     3661 tgataattta gaaaaagata ctaaaaatac ttcaaatgat aaaggcaaaa taagagtgtt
     3721 agatgtagat aactataaaa agtcattaga agaaaataaa attgatgctt atataaagat
     3781 ggaagaaaaa aaatcatcta taaattatca aatatatata aattcttctc aagaaaattc
     3841 ttctaatgca ctaaaaagaa ttgaaactgt tttggataaa tataaaagat ttaccataga
     3901 aaaaacttta tctgaaaaag gattagatgt acaagctact ttagaaccaa taacatatag
     3961 cactgtagat gttgcaaaga cggaagaagt ggcaggatac tttttaggtc agatacttcc
     4021 atttatatta ataataggag ttttactagg ttcaatatat ccagcaatag atgttatggc
     4081 tggagaaaag gaaagaggta cattagaaac attatttaca ctcccaatat caaacttaga
     4141 actggttatg ggaaaatata tggcagtttc tcttagtgca atagtaacag caattttaaa
     4201 cattttatct atgggactga ctatggcatt tattttagtt agtggaggta ttagtagcca
     4261 atttggtttt ggaaacttta attatggaga tttagtctta ccaattataa ctactttaat
     4321 ttgcatatgt cttttttcaa tggtagtttc agcaataagt atgtgtgtat gttcattagc
     4381 aaaaagtttt aaagatgctc aaaactacat aacacctctt atgttaatta ttatgatacc
     4441 atcatatgtt tctatgatac caaatatagt attagataga gtaacagctg taatacctgt
     4501 agtaaatata tctttactta taaaaagtgt attatctttt aaaagcgatt taaatttaat
     4561 agccttagtt ttagcatcaa atgtagcctt tgttatattg gcaatcatac tactgtctaa
     4621 gatgttcaat tctgaggaaa tactttttgg taatagtaag agtttctctt tcttagagaa
     4681 aagaagtaat ataaaaaaag ggtctatacc aactgtaagt gatggtgtta ttttatatgc
     4741 agtaggatta attctattga tttatgttgg ttctttagtt caaattaaat ttggtatggc
     4801 aggtattata atgacacaat tcatgataat ttctttacca ttattatttg catactatat
     4861 taaagctgat tttaaagagg tatttagctt gacagttcct aaattaaagc atgtgtttgg
     4921 gagcattgtt ctttggattg gtggatacat acttattatg attataacac agctaatttt
     4981 attcttattt cctcaaaata tggaagttgc tgaaagttta aataaggctc tttttatcaa
     5041 agatagtgtt ttactgaatt tactagcaat agctttatta ccagctatat gtgaagaaat
     5101 gttttttagg ggatttatat tttcttcatt tagtaaatca aaagataaaa ataagtctat
     5161 caagctagct ataatatgca gtggggtact atttggtatt atgcatatgg attttattag
     5221 aataattcca acatcaatat taggtattat atttgcatat agtgtgtata aatctggttc
     5281 aatatttgta tcaatattat tgcatttttt aaataatagt gtagcagttg tgttaaatca
     5341 ttatacaact ggaaatataa ccaacttata taaatttgtt gaagttgatt tttcgaactt
     5401 aaatgtactt aaatttgcct taattcttct aataagtctt atattaatta tgttaggatt
     5461 aagagtttta gatagaaagt ctttaagaaa ttaagtataa agttattata tagattaaaa
     5521 tattaataag cactaaagta tatggatata tcttgtatat aaaaatactt tagtgctatt
     5581 ttatatattt taattatatg aattatttat cgtttcattt atgtaatgaa aatgttatat
     5641 aaatgaaaca ataaataatt tttattttag aaatttatat ttaaataatc aagttgaaag
     5701 tgagatacta aaaaaattaa tttaggaatt atttgattta ttcatttata aaaattaatt
     5761 actgatttgt cgaaaccatt gtaataagaa aaaaatgaaa aaataaagtg tgaatatgtt
     5821 gcaaatactg tattttaata aaaagtagtc atttcttgta aaatggatag ttttgaaaag
     5881 aaaatattaa aattataata taaaaataaa atttttcaga caatttaaac aaaaataatc
     5941 accttttaat aaataattat atgccaaaat aatccaattt attttctatt atacctatat
     6001 gaaatatata aatcaatagt taagacaatg aatatgctac attctataat tatagtagca
     6061 gaaaatttta caaaattaaa gtagata
//
LOCUS       DAEOTL010000146         5908 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEOTL010000146 DAEOTL010000000
VERSION     DAEOTL010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5908
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.148"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            35..688
                     /locus_tag="KRH82_003741"
     CDS             35..688
                     /locus_tag="KRH82_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBG8656989.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNSFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     gene            829..2100
                     /gene="brnQ"
                     /locus_tag="KRH82_003742"
     CDS             829..2100
                     /gene="brnQ"
                     /locus_tag="KRH82_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBG8656990.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            2302..3489
                     /locus_tag="KRH82_003743"
     CDS             2302..3489
                     /locus_tag="KRH82_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBG8656991.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(3719..5743)
                     /locus_tag="KRH82_003744"
     CDS             complement(3719..5743)
                     /locus_tag="KRH82_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBG8656992.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLGLDEKLIKSPSLMEYMPNSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCIEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
BASE COUNT         2071 a          706 c          928 g         2203 t
ORIGIN      
        1 atcaaaaata atataattta tagtggaggg gaaaatgact aaaattatta aagtgcaaaa
       61 acctaaattt acaggagaat tagaaattat tgaaaatctt gaagatatac ttgaagatat
      121 atttaatgat gaaaaaatat ttaataaaat tatagaaaat gaagttataa gtgatttaga
      181 ttctgtaaga gttagctttg aatcttgtat atttagaaat gtgtcttttg aaaattgtaa
      241 tttaaaaaag attgatttac ttgatgtggt atttgaaaac tgcaatttat caaattcatt
      301 ttttgatgga ggaagtatat acagagttga atttaaaaat agtaaattga taggagttag
      361 atttgatgat tgtatactta aaaacgtttt gttcaaggat gttttaggta agtattctaa
      421 cttttcattc tctaaattta agatagtttc tatcttagat tcaaattttg aaaattctgt
      481 atttcaagaa gtaaaaggtg acaatctagt atttgagtat acaaatttaa aaaaagcaaa
      541 ctttaatgga actaaacttt ctggcataga ttttactact aataatattg agggaattga
      601 gattggtata gatgatatta gaggagcaat ttttgatgtg tcacaagcaa ttgatttaac
      661 gaaattgatg ggaattatca taaaatgaaa aaaaaattca taaaacaaat tgggaaaacg
      721 ttaacaatgt gtgaattttt accagattga catttttctg aaaataaagt aagattatct
      781 taatattcaa aatattttca aagggggtaa tttagtgtga gtaagcagat gagagatatt
      841 tttatagttg gttttgcttt attttctatg ttctttggtg caggaaatct tatgtttcct
      901 ccatttttag ggatggaatc cggcaaagac tggttaattc ctcttattgg atttgttgtt
      961 gcagatgctg gtatagcaat gcttgttatt atagcaacag caagatgtaa gggaagcatg
     1021 gatgatgtac ttaggagagc tggtaaaggg ttagcaagag taatgagtgt agctgctcta
     1081 gcatgtttag cacttcttgt aataccaaga acttgcgcaa caacatatga aatgggtatt
     1141 atgcctatat ttggagacca tggtccagta gctaaagctg tattttcaat aatcttcttt
     1201 gggttaactt tagcatttac tattaggtct tctaaggtta tagacataat aggtaagtat
     1261 ttaactccag cgttattatt agtattattt gttttaatag taaagggtat aatttctcca
     1321 gcaggaccta tgagtcctga gcatatgata gataaaaatc tatttggtga aggtatatca
     1381 caaggttatc aaacaatgga cgctctaggt gcagcatcta tggcaactat aatgttgatg
     1441 tctataatag ctaaaggata tacatcagat aaagaccaaa taggaatgac tattaaagct
     1501 ggttttgtag cctgtgtatt tctagcagta gtatatggtg gtcttactta tttaggtgca
     1561 acagtttcaa ctttatatga tactagtata cctcaagcat ctttattagt tgaaataact
     1621 agtatattgt tatatggtca agtaggaaag gtaattttag gtgtaattgt ggcacttgcc
     1681 tgtctgacta cttctacagg tttaacagca tcaatatcaa cttattttga aggaataagt
     1741 aaggcgagtt ataaacaact ggttataggt atatgtgtag ctagtatgct tatatcaaat
     1801 ttaggtgttg attctataat agccatatca gttccaatcc tacaaactat atatcctgtt
     1861 ttattagcaa tagttgttat ggagttggct ggtaaacata taaagaatga taatgctttt
     1921 aaaggtgcag catatgttac attagtgatt agtttattat cagctataaa tggaatgaca
     1981 ggagctgttc catttataca aagcttgcca cttgcaggtt tgggctttaa ctgggtaata
     2041 ccagctatat tgggtggaat agttggtaac tttataaaaa gcaacaaaca agtagcataa
     2101 taatttgtaa ttaatttaat tttataatat attaattttt agtactatgg gtaggtttaa
     2161 tctaaaccta atctacccat agtacttttt agattggatt ataatagcat gtatataatt
     2221 ttttataata taatttttct ttgaagtatg ataaaattag taatagtgat aagaatgtac
     2281 aaatttagga ggttttaatt aatgcttaga aaaataacag catttatgct atccatatgt
     2341 ttaattattg gacttacagg ttgtagttta cttgtaggca agaaagataa agagaaaatt
     2401 atagatgatt ttaaagttgc agtggtaact caaccattat ctgaaaataa agtacaatac
     2461 aatatggtgg aagagatggc aaaagaatat gaggaagaga ataaaattga taaagacaaa
     2521 gatggtcaaa ctaaagttaa acaaactata aagcatgttg tattgccaga gaattttact
     2581 tctaatatag acagtgctat taataagata gtaaagttgg ctgacgataa agaagttcag
     2641 gctattgtag tttcaactga ccaagcaggg cttttacctg ctttacaaaa ggtaaaggaa
     2701 aagcgtccag aaataataac tatttctgcc cctatgggag atgataaaaa ccaattaagc
     2761 caatttgttg atgtgaatct aggggttagt gcagaggaaa gaggaaaagt attagctgaa
     2821 cgttcaaaag aaatgggagc aaaagctttt attcattatg cctctacaga tgatttgaaa
     2881 gatgttaata tagccaaaag attagaaatg attaaagaga cttgcaaaaa tataggattg
     2941 ccatttgtac aagttaatac tccaaatata aatactgaag aagacaaaaa caaagttaaa
     3001 cagtttttaa atgaagatat tgaaaaacaa gttaaaaaat atggaaaaga tataaatgta
     3061 tttggtgtaa atgagtatat ggatgaagtt atattgacta aggctttaga attaaagtat
     3121 atagttgcag agcaaagcaa tccatcacca atacaaacat atcctagtgt tatgggtcta
     3181 aaaatatctg aaaaagatgc tcaaaattat gataaaataa acgacatgat aagtgaaaag
     3241 gctaaggctt ttggcatgtc aaatagactt ggtggatatc ctatgccaat ggatgctttt
     3301 ctaccatcag tagcaattta tcttgctact gaaatggtga aacaagattt aacacaagaa
     3361 gatgtatgtg acccagatta tttagaggcg tttacagaat taagatttgg aatcggttca
     3421 gaatttactc ctttaacaga ggtactttat aattatcaat cagtaatttt aagccaatta
     3481 atttattaat attaaggaag tgtctcaaaa tgaacttttt agtttatgag gcactctttt
     3541 tctattaaat caaatatatt tttatctttt taacaattaa aaagaagctt atccctatat
     3601 tgagatagct tcgtttttaa tataaataag ttttattatt ttataaaaaa tttatagaaa
     3661 aataaaaaat tataattata tataaatttt gataaagtaa agatgaatta ctataggttt
     3721 aaattatatt attttctatt atttttatgc ctttctcagt tattgatgag ccttttcttc
     3781 ctttactaga aattaagtat ccattgcgtg tcaaatattc tagcatattt cttacttcgt
     3841 attctgtgac attatattcc ataaatttca ttaactttgt cctccccatt ggtttcatgt
     3901 gcaatgattt taggatagaa atgcatatgt ttttgtcata ttggtttaaa tcattgaata
     3961 tggacatatt acttgacata tgattattat ttaattttga agatatgttt tgaggtaaat
     4021 catttattgt aagataattg gaacccatgt aagccatata ttcaatacaa tttctcagtt
     4081 ctctaatatt ccccatccaa gtgtatgaat ttaaagcttc taaaagactc ttatcgagtt
     4141 ttatgttttt atagggaagt tcttttaaaa atgattctaa aagaagaggt atatcttcta
     4201 atctctttct aagaggaggt aaatctaaag tgaacatact tatcctataa aataaatcca
     4261 tcctaaattt attttctata attaatttct ctaaatcttt atttgtggca gctaatattc
     4321 tcacatcaat tggaataata cttgtaccac caatttttct aatttctttt tcttgtaaga
     4381 ctcttaaaag tttaacctgt aaatcatgtg gcatatctcc tatctcatct aaaaatatag
     4441 tgccagtgtg agctaattcg aataatcctt tttttccacc tttttttgct ccagtaaaag
     4501 aaccatcttc atatccaaat agttcacttt caagtaattc acttggtaat gaagcacaat
     4561 ttattgctac aaaaggttta ttttttctat ttgaatgatt gtgtattgac tgagtaaagg
     4621 cttctttacc tgttcctgtt tcacctgtta ttaatatagg attatctgta agagccattt
     4681 tttttgcctt tttaatacaa tcttttataa tagaactatt tccaataata ttattaaatt
     4741 tatatttagc tacataacct cttttgacag aatcacttct tattttttgt tctaatattt
     4801 ctatattgtt tacatctttc aatgtaatta agcaaccctc tatattttta taaagataaa
     4861 atggtttttt agaaagtatg aattttttat ctatttcgtc tatgtatata atcatattat
     4921 cgatatttaa gttctttgta attttatcta agaaactatt tggcatatat tccattaagg
     4981 aaggtgattt tataagtttt tcatctagtc ccaacatatt aagtaaagac ttatttacaa
     5041 aagtaacctt gttaaaggtg ttgaaaaata ttagaccatc acctatttca tcaatggtca
     5101 tgtaaagtat agtttttaat ttagatatat tatctaatga tgtatttaag aaatcatgac
     5161 ttagtgtctc tttggacaat ttgtatagtt tttctataaa tttctcattt tttagtttta
     5221 atactactaa taatgacata tatgtatcta atgagatttt tctccaacct aaatcaacaa
     5281 tattttttat gtattttggt ataaatctaa tctgacctgg tgttatagct gtatctaaat
     5341 catatatttc atcacaatct ggatatgtcg gtacaaaatc tatatgattt ataccaattt
     5401 tatatagata agtagccatc tcaaatgctg aagttttatt ggttgtcata agtaacgatt
     5461 ttgtacctgg aggtagtttc atcatttttt catatccaag ttttgaaagt gctttcgttc
     5521 catgaataat ttcaatatct tccttaaaat gttttattaa aaaattacta gttaaaggtg
     5581 atagagaaag cactacatct ccctctaaat tttcttttat tccatcaagt atattttgtg
     5641 tttctatgat tatttcgtct ccaaaaaagt ttgttaattc ttctttgtag tggtcactat
     5701 tcaatttatc atatgttata aggattaact tctttttatc cattttattt ctcctaacaa
     5761 aatagtattt atttttaaag tatttaaagt ataaggcaag ttatattata caacaaatag
     5821 tagtataaat ttatatattt gattaaataa taggtttttt taggatttta tcctataaaa
     5881 acctatttta aaattatttt tgcaagat
//
LOCUS       DAEOTL010000147         5683 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEOTL010000147 DAEOTL010000000
VERSION     DAEOTL010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5683
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.149"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            240..1067
                     /locus_tag="KRH82_003745"
     CDS             240..1067
                     /locus_tag="KRH82_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBG8656993.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
     gene            2089..2553
                     /locus_tag="KRH82_003746"
     CDS             2089..2553
                     /locus_tag="KRH82_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8656994.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFISLLDEGSSVFFGIGMKPNYCGMGIGKEIIGLGLQEC
                     RNKYSTKPIVLNVRTWNMRALKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(2820..3464)
                     /locus_tag="KRH82_003747"
     CDS             complement(2820..3464)
                     /locus_tag="KRH82_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656995.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGGVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(3394..4683)
                     /locus_tag="KRH82_003748"
     CDS             complement(3394..4683)
                     /locus_tag="KRH82_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8656996.1"
                     /translation="MNLFIKECKNILKSMIYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWFYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIIINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(4680..5552)
                     /locus_tag="KRH82_003749"
     CDS             complement(4680..5552)
                     /locus_tag="KRH82_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8656997.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQSLIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEEKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
BASE COUNT         2057 a          781 c          706 g         2139 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacgaatg ataaataata ctcaaaatgt
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattacttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttatttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acaccttttt aaaattatat ctgtagaaaa
     1561 tatcatttag agctataatt aaattaactt attaaatttt agaaaattta ttaaaaaata
     1621 taagttaaat taatattttt aaagattctt tttgtaacta ctagaatact aatttagtag
     1681 ttattgtatc tctaaagttt aagcatggat agatatacat ttgataattt gcctataatt
     1741 tacctactac ttggagtatt ggagcaaata caatatatta ataataagtt cctaaagcca
     1801 ataaattaac taatacacat aaagatattg atgttgatta tacaactata agaaacggat
     1861 ttaacagaat ttaatcaagc taagaaatta tatatatcgt gatgtttttg aattagaagg
     1921 taattcaaaa ttagtttata gtcttctgtg aatccaataa aaagtacagg gtacaagaat
     1981 tgttagtaaa atttttaaag attttatgga taaatataaa tagttttact tattttctaa
     2041 aactttaaaa taccattaat taccttaaat attttaatag gaggacatat gaatttaaat
     2101 aaagttaaat ttactgaaga acatgctatt gaagttacta attggaaata tgaaggtaaa
     2161 tattcaatat acaatctacc tccatgggag gaaattaaaa agaagaattt ttcactagca
     2221 aaagaagata aaagaaaaaa ttttataagt tttataaatg acaataaaga attgataggt
     2281 tttataagct tattagatga aggaagctct gtattctttg gtattggtat gaaaccgaat
     2341 tattgcggaa tgggaattgg taaagaaata attggcctag gattacaaga atgtagaaat
     2401 aaatatagta ctaaaccaat tgtattaaat gtaagaacct ggaacatgag agctttaaaa
     2461 tgttatgagt ctcaaggatt taaaatagtt gagactaagg tacagaaaac gcatttagga
     2521 gatggagaat tttttgttat gaggtatcaa tagtttataa caatagtctt attgttaata
     2581 caacaattaa aataaaaaaa tacatatgtg taggtcatag caataagtgt ctttgaaata
     2641 taaatttgag agcttttgat aaaatttggt atacatatat attttatact acggatatat
     2701 aaatctatct acatacataa agagattgta agtaggtttg tgtatataaa aatagattta
     2761 tatttcataa atgtaccttt tatttgtatt acctttattt tatctaagct ctcattttat
     2821 tatctaatct tcctttttac tggttttatt aagagagatg caattatcaa cacaacactt
     2881 ccaagtatca gccaatattt ctcatcaaaa ctaccttgac tcatagacat tataaaaaat
     2941 tttccaacat acttgccttt agtcatcata tttaaaatta aatatcctat agatatcata
     3001 taacctatga ttgtattatt aaataaattt gagaaaaaca ttcctaaact tcctataaac
     3061 atagctgatg cgaaacttcc aataatatac tcaactactg gaaaattaca tccaagatat
     3121 attaaaacat ttacaaaacc tatgattaat accactatac ctataattga catcagtatc
     3181 ctaattaatt gtacaataac ttgagataat gcttttgaag atactatctc atcaatttct
     3241 tttgattgct ctagcgaaaa tacaggtacc aacattactc cccctattat tgcaacataa
     3301 ttttctaaac atatagctgt tgaaattctg tctaaattag ctactccttg tattagagga
     3361 atcatacata gcaatataat tgaacatatt aaattagtta aagtgcttaa tttgaagttt
     3421 tcttttatta gaactaaaca gttttgaaaa ctttgcccaa acatcaagat tcccccttct
     3481 tttttgctca tataagaata tagctaacaa aacaagcacc aatgctccca agcttatcac
     3541 aattctatta attataattt gattgaagtt ttgtataata atatctccat ttaatacact
     3601 attatgtctt atcattagcc ccattgttga ataatcacct ttgagtcctg tagaatttat
     3661 actgtaaaac caccaaatta attgcacaat aattgctact ggtgtatctg ttaatatagt
     3721 aatactcatt cctacagcgg taactatcat aagagttggt agtatccacc ataatgtata
     3781 ttttataaat gctaagttat caatagatat acctttatct ttagcaaaga aaatcaaagg
     3841 aagtaaatct ttcataccta aaattaatac aggcaatatc atcataaaga caagtgcaaa
     3901 atatcttgat aaaactattt tgcatgaaga tacttgtttt gaataaataa tctctctcat
     3961 tcttgaacgc ttatctttaa gtgacataaa aactgccaca aatactggaa atatacttaa
     4021 aactatacct atataatcgc aaaaaattct tgcataccca ttactaactt tatctttttg
     4081 tattgtatag ttgtaattct tcatagcttc atcataggta actggaacta ctccaaatct
     4141 ttgtaacttg tcaaaagcat atgcagaccc tcctcctaaa atgtcgtcta ctctttgcat
     4201 tatttcttca aatctttcaa gagatacttt agaataatct atttttatac tttcatcagt
     4261 tttccaaagt gaatttattt cgctaatact tttaccagtt atttcttcta tatatttttc
     4321 tatggtcttc gttttatttt ggtctaattt tatatactta actacccctg ttggatacgt
     4381 tgtatatgtg tttttttgat attctctaat taggtttata gttgcatttg gaatgacctt
     4441 ttctgttttc atagattctt tttgaccata tggatattga ttgtgtacag aataatattc
     4501 ctcaatattc tctacttttt gtggagcaac taatggattt ccatcattag gaatattttt
     4561 acttacatca tttgaaactg aacttccaag ttgagaaata tagaaaaaaa ctaaaactac
     4621 aataaaaata taatatatca tactctttaa tatattttta cattctttta taaatagatt
     4681 catatattat ctcctcccat tataagcata tagccatctt caatagttgg attacaattt
     4741 actgctgtct caaaaggttt atcatctgat ataatcctaa gtatagcctt tccaccatga
     4801 gtcaacattc ctataactat aaatctactt tttatatttt caatatcttt tttatctact
     4861 tcaatactat atactttctc ttcagctagt tttgctaatg cttctgttga gccattgtat
     4921 atgacttttc cactattcaa tatagctacg ttttcacatg tagcttctat atctccaaca
     4981 atatgtgtag ataaaataac gattctatca tttgcaattt cgcatagtaa atttctaaat
     5041 cttatacgtt cttctgggtc aagacctgct gtcggctcat ctactattaa aactctggga
     5101 ttatgaatta atgattgtgc tatcccaagc cttctattca tacctccaga taaagatttt
     5161 actttcacat tttgataatt agtaaggttt actttgctta ataactttgc tataattttt
     5221 cttctttttc ttagtggtat atccgataaa actgctaaat aatccattgc tttatatact
     5281 gtcatgttag gatacattga aaagtcttgt ggcaaataac caaccatatt tctaatttcc
     5341 ttagtattct caataggaac tccacacata tgtattgaac cttctgtttt tgataataaa
     5401 gtggctaaaa ttctcataaa tgtggttttt cctgctccat ttcttcctaa aagaccaaac
     5461 ataccactgt cgatttcaag atttatatta tcaagtgctt gttttttccc aaatcttttg
     5521 ctaagattgg atactgctat tttcatttcc atatataaat acacccccag aaacaatttt
     5581 atagaatttt atttttataa atttttactg tattttcata ataaattcta aaacttaaga
     5641 tattatttat aaatttctaa attttttcta aagattttaa ttt
//
LOCUS       DAEOTL010000148         5645 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEOTL010000148 DAEOTL010000000
VERSION     DAEOTL010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5645
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.150"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            455..859
                     /locus_tag="KRH82_003750"
     CDS             455..859
                     /locus_tag="KRH82_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBG8656998.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(1116..2111)
                     /locus_tag="KRH82_003751"
     CDS             complement(1116..2111)
                     /locus_tag="KRH82_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBG8656999.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(2395..3231)
                     /locus_tag="KRH82_003752"
     CDS             complement(2395..3231)
                     /locus_tag="KRH82_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBG8657000.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(3719..4282)
                     /locus_tag="KRH82_003753"
     CDS             complement(3719..4282)
                     /locus_tag="KRH82_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657001.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(4380..5309)
                     /gene="glsA"
                     /locus_tag="KRH82_003754"
     CDS             complement(4380..5309)
                     /gene="glsA"
                     /locus_tag="KRH82_003754"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBG8657002.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
BASE COUNT         1887 a         1028 c          545 g         2185 t
ORIGIN      
        1 ttaactcttt tagatactta gcctttttaa tctattcaac cttttttacc cacttaacct
       61 tcttaccttt taatataaac tctaaaactt caaatatcat tagttatatt ttgacattct
      121 tcctatagtt aatgcaaaaa gattgatttt ttcttataat taatatccca tttacattgc
      181 catttattaa gtctttactt gacttatatg gatttctttt tactctcttt actaaactat
      241 acttattaat attatgaagg tcttataata gtctaatatg aatatgtcca tcatatatca
      301 aattttaaaa tttgtaagca aaatacttat cttatattac tacatctaaa gtggaaaatt
      361 ttacaaacaa gctctgtaaa aacactttaa ataacaattt gcttttaaat catatacaga
      421 ttataataaa tactgtataa ggatggtgaa aaatttgatt aaaataacaa ttccaggtag
      481 acctattagt aaatctaatt ttaagcttca taacataaat ggtcaagcat ggatgccttc
      541 aaagggaaaa tattctaagt atcttgcata cgaaaacatg attgcaggtt ttataaacca
      601 acagtatcaa ggggaaactg ttgaagaaaa tctaataaca gtcttgaaat tattcttccc
      661 aaataagaga atgggggatt tacataatta tccaaaaagt atttgtgatg gtattgaaaa
      721 aagtggaata ataaaaaatg ataaacaact taagccagta cttttatttg attttataga
      781 taaagataac cctagggttg aaattgaact ttatccagta tctaaatacg atatatccta
      841 taatattttt gaaaaataaa gattttatgt gttattcgac attatattga tactccagta
      901 tttgaaacta tactaataca acaataataa ttgtgttatg tctatactca aacaaatgtt
      961 tttaaaaagc attaagtaaa tatttaataa gtattaaaca aatattaaat ttatataata
     1021 gctataacta tgtaaattta atatttgtat ataagaccac atctaataaa aagaaatcgg
     1081 agtaaattta atacaccgat ttcaataaat aaaatctatc ctagcttttc aacaacagtc
     1141 ttaagcattt ctcttatagg aagttcatat ggacatctac tctcgcaaag cccacagtca
     1201 atacactcag taggtttaac atccataacc tcatattttt ctttagccca ctcttttaat
     1261 ccatatctag tataataacc ttcacataaa aaactcaatg gtatatttat tcctacagca
     1321 caaggcatac aatattcgca tcttctacag aattttttac ctaaagaatt tcttatttct
     1381 tcaatttcct tattatcttt ttcatctagc acaagatttt caagtacagc gacattttgt
     1441 ctaacctgtt caacactctc catacctggt ataactacat ctatgtaatc tttagatagt
     1501 atatatttaa tagccagtgt tgcattgtct aaagcacctc cagctaaagg tttcattact
     1561 attatcccaa ttcctttttc atgagctttt ttaaacactt catctgcttg tccttcaact
     1621 atattgtaag ggaattgtat agtgtcaaat tttccatctt ctatagcttt ttctatagta
     1681 tttaaattgt gactagttat accaatatgt tttatcttac cttgctcctt tgcctctaaa
     1741 agggcactat aagccatttt atctttaaaa agattatcat actcctcttc tttaacatta
     1801 tggaattgat ataaatctat aaaatcagtt ttaaaattat ttaaacttat ttcaacatct
     1861 ctcttcattg aatcataatc tctggacata cttttagtag ctaagaaaaa tttatctctt
     1921 tttccttcaa tggcaattcc gattgcttcc tcacttattg tataccctct tgcactatca
     1981 ataaagttta ttccttgttt ttctaactca tttataacta agttagtatc atcttgagta
     2041 atcctttgta ttggaatgcc cccaaagcca actctcttta ttttcatgtt agtattgcct
     2101 aaatttctca tatctttccc cacctaactt ttaataattt tttatataat ataaatatgt
     2161 catctttaat tatacaacaa attatgagaa tctttgcaat atatttacat actattcata
     2221 atataattat attttatatc agtctattca taatataatc atactttata cccagttaat
     2281 ttgtatacaa tttttgttat tcctatccat taatttaaat tatcacattt gataattgta
     2341 tctccaccct aattatgttg agggcggagt atttcacata tttttaataa aggtttattt
     2401 actagatagt atttctttta tcattttaag ctctctcttg tgaccttcat catcaaaagg
     2461 agtttctaag aaaaatggta aatgttttag actaggatgt tccataaaat caattaatgc
     2521 ttttaatcct atctttcctt cccctatagg agcatgtctg tcttttttgt ctccaaatgg
     2581 catcatacta tcatttagat ggacagtttt caatctttct atgcctataa ccttatcaaa
     2641 ttcttccaaa accccatcta aatcattcac tatatcataa ccagctgaaa aaatatgaca
     2701 tgtatcaaga cacacaccta ttttttcttt atgctcaatt ttgtctatta tactttttaa
     2761 ttgctcaaat ttaaaaccta tttcagttcc ctttcccgac atagtttcaa gaagtatagt
     2821 tatattttca tcacccttta tggcattgtt caatcctttt actattctat ctatgccaaa
     2881 atctacacca ccacctacat gacttccagg atgaaaacac atgtattcaa ttcctaatga
     2941 gtccatcctt cttatatcct catctatcac ccttgttgca aattcgtata catcatcctt
     3001 tgtaccaccc agattcatag tatatggtgc atgtgcaagc agtggtgcaa aattattttc
     3061 ttttctaatt tcttgaaatt taattatatc tttttcatca aattctttag catttcctcc
     3121 tcttggattt ctactaaaaa attgaaatgt atttgcacca atatatacag ctgtctcagc
     3181 cgcattagca aatccttttg ctattgaaag atgtgttcct aatttaatca tattaatctc
     3241 cttttatttg tactactact tgtactcaat tttaattttg aactactcca ccttaactac
     3301 atttagccaa catatgaaga tggagattcc tatttgatag tactttttca ctaaaaattc
     3361 ataagctcta agggatgttc tatcccaact aatctcattc ctcttttaac atatttctag
     3421 cattgattta atttatatta atttttaatt ttaatattta cactttaatt atacccattt
     3481 taatcaattt caaatattat aatcttacat actttgtata ttatctaagc acttctcaga
     3541 tagtgtatac atcttatact atacatatta tttacaaata caataggtat aagaaaacaa
     3601 aaaaatagag attaaaaatc attgttttac ccataccaaa aactattttt tgattattaa
     3661 gtaaattttg atgttcaatc tctaatatta tatctttaat taatccataa ttaattctct
     3721 aactaggaca ttcctcctca agagtaggaa ctataaccat agctatatca tacttagaac
     3781 cttcaacatt gtgttgtctt ttatttaaaa tttcatctat ctttgacttc atagtgtcac
     3841 taagttcaac taattcatca tgagtaagag aaatatcatg ataatcaact atattttcat
     3901 tttctaaaac atcttcctct gctgccttat aaaaaacttc actcatattt tcaaattttg
     3961 atatgtacaa ttcttctttt tcttccccat tgtctaaaga aaaattaagt atcctattcc
     4021 ctataaccac attttttgca cttggataat agtacttttc cacaatcccc gactttattt
     4081 tttcctcaac taattctaaa ataccaactt tgtataacat ttttatatgg tagtttattt
     4141 ttgcatgagg ttcttccaat aattgagata attgttttgc tgacaatggc gatttgtcaa
     4201 atgcttttag aatatctatt ctacgtggat gcgcaatagc ctttatgcac tccaaatctc
     4261 gtaataccaa tacctctttc attgacccct cctaaaaaat ttatttaatt catatttctt
     4321 tacaatttaa ttatatatta aattatatgt tgttgtcaaa aaaatccttt cttaatattt
     4381 taaaaaatat ttaatttgag tttatttgac aactcctcta aaactttaac tcctgcgacg
     4441 ctgttacctt ttttgtcaag cgcaggtcca taaacaccaa tccccatgcg tcccggcaca
     4501 gaagccatta taccaccccc aactccagat tttgcaggaa tgccaacttt aatagcaaat
     4561 tccccagaag catcatacat tccacaagtc atcataaatg tcttgacaat cctagaaacc
     4621 atttcactca ttaaatgctc accattttct atatctactc cataatttgc aagatttatt
     4681 ccaattctcg ctaaatctac agaatctatc tcaattgagc attgtttaaa ataaaggtct
     4741 agaacatctt ctacattccc tctgataaat ccatcacttt tcaataagta agccatagct
     4801 ctgtttctat ctccagtcat tttttcagac ttatagacat catagtttat tcctatatta
     4861 tcattttttg ctaactttct aaagaaacta agcattcttt cttctttttc ttctaaacaa
     4921 ctcccattta taagggaagt ggttactata gcccctgcat ttatcattgg attacagggt
     4981 ttttttgtgt cattaatttc aagtttcatt attgaattaa atgggtcccc acttggctcc
     5041 attccaacgt ttgaaaaaac gtcttcccaa tcattatcca taagtgccat agcaagcaca
     5101 attggttttg aaatactttg tatagtaaac tttgtgctac agtttccagc actataaaga
     5161 ttattttcgc tatctatgat acaaattcct aaatcatttc ttctagcgtt ttttaattct
     5221 ggtatgtaac tagcgacttg tccataatta gtatacttct tattagaact tataatttct
     5281 tttaataatg tctcatctaa cgtattcata tgcacctctt atattatgtt atatattcta
     5341 ttttagcaca agtttatact ataataaaac aatgttaaaa aaaattatac tttaaaatta
     5401 ttttctacaa gaatcaattc atttttcaaa caatttaaat agtttaaaga gcttaataat
     5461 ttagtaattc aataatttaa caacctagca atttagtaat ctaataatcc agtaatttaa
     5521 caacctaata atttagcaat ctaataatct aactatctaa taatccagta acttaacaac
     5581 ctaataattt agtaattcaa caatctaaca attcaataat ttaacaacct agtaatctaa
     5641 ctatc
//
LOCUS       DAEOTL010000149         5533 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEOTL010000149 DAEOTL010000000
VERSION     DAEOTL010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.151"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(260..976)
                     /gene="dapD"
                     /locus_tag="KRH82_003755"
     CDS             complement(260..976)
                     /gene="dapD"
                     /locus_tag="KRH82_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBG8657003.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYDDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(1200..1949)
                     /locus_tag="KRH82_003756"
     CDS             complement(1200..1949)
                     /locus_tag="KRH82_003756"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBG8657004.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(2016..2903)
                     /locus_tag="KRH82_003757"
     CDS             complement(2016..2903)
                     /locus_tag="KRH82_003757"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBG8657005.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(3020..4021)
                     /locus_tag="KRH82_003758"
     CDS             complement(3020..4021)
                     /locus_tag="KRH82_003758"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBG8657006.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(4446..5327)
                     /locus_tag="KRH82_003759"
     CDS             complement(4446..5327)
                     /locus_tag="KRH82_003759"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBG8657007.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
BASE COUNT         1851 a          976 c          663 g         2043 t
ORIGIN      
        1 aaattataaa aagtttaata gtttattaca ttgatatatt gaaaaattga aggaaataaa
       61 aatacttgtc agcaagaaat aaaaatgata taagaatgaa taagagaatt gtaaaaaaat
      121 aaaatgatta taaataaaag ataaaaatat tgtaaaaaag agggtgcctc tggtgaatta
      181 aattcacaca gagacacctt tttaattaat tttttaaatt agtatattat tgtttaatta
      241 atagtatagt actatttaat tagtctaaat ttctaaggtc ttccataagc ttagttttgt
      301 cagccgtttt ttcatctttc atttttataa ctttagcagg agaaccagca acaacagcac
      361 cagcttctac atcagtagtt acaacagcac cagctgcaac aacagcacct ttaccgattc
      421 taacaccttc aagaataact gcattagctc ctattaaaac atcatcttca actataacag
      481 gagtagcaga aggtggctct aaaacaccag caacaacagc accagcacct aagtgaacat
      541 ttttaccaag agttcctcta gctccaataa cagcattcat atctaccata gaaccttcac
      601 caataacagc tcctatattt ataacagctc ccatcattac aacagcattt ttttctatag
      661 taaccatgtc tcttattatt gcacctggct caattcttgc atgttcactt aaagtatttt
      721 ttagaggaat agcagaattt cttctatcat attctacatg agtatctgtt atatcatttc
      781 catgtttatc taatacttcc attatatcat catagtcacc tacaaatata taagaaccat
      841 tatttccaaa taccttaaat ttatcagttg attggaagtg taaagagtta gtatttacat
      901 ataccttaac aggtgttttc tttttaactt cttttatata ccttgctatt tcataagcat
      961 cgtttaaatt taccatttgt taattctcct tgtatttcat tatatttctt ttattatata
     1021 cttatttgtc aattttagta tatacttact tcttattatt tatattttat tttagttagt
     1081 ttttattgta tagacatagt attaaataaa tttattatat atgtttgatt tgtattgcat
     1141 attattatat atatattgta tatgtttaat ttatattgtg tattattata tttatactat
     1201 tatcccaaca tgctgtccat attataaaat cctggttttt gcttaactaa gtatttggca
     1261 gcagctatag aaccacttgc aaagatacca cgagattgag cttgatggct tattgtaaga
     1321 acctcattgt ctccagcaaa tagagcatca tgttcgccaa caatatttcc acctcttata
     1381 gcatgaatac caacttcatt tggttgtctt tttgcactac gaccatatct accataatta
     1441 ttttcaacgt ttggcaaaac ctcttttata gcgttagcaa tcataacagc tgtgccactt
     1501 ggggcatcta cttttctgtt gtgatgtttt tctattattt ctatatcaaa tccttctagt
     1561 aatttagctg catctttaac caattttact aatacattta caccaagaga catattatat
     1621 gattggaata caggaataac tttagccgct tcacgtattt tgttcatttc gtcatcatta
     1681 tatccagtag tagcaattac taaaggtgtt ttagtcttta aaacgtaaga taagatatta
     1741 tctaaattag agtgatgaga aaaatctata actacatcag cttcctcaac tatagtactc
     1801 atatcttcat aaattttaag gtcgccttca tagctatcca gacctctagc tgcaacacaa
     1861 accaattcta attcattatc ttctcttata gtatcggcta aaatcttacc catttttcca
     1921 tcataaccag ttgctataac ttttaacata atttcctcct atgattaagg gctaactttt
     1981 gaccaaactt actttttacc atgcattaat ctttactatg cattaacttt tagcccaaag
     2041 ttaactaatt ctttctttaa tacttctaaa tttgctgggt ccatttctgc tagaggtaat
     2101 cttaaatctc caacattgaa tcccaataaa ttcattgcag tcttaactgg tataggattt
     2161 acttctataa ataaagctgc gattagagca tccataccaa gttgtaattt tctagaacct
     2221 tcaatatcgc cttcaaagaa tttagctacc aaatcgtgag tttcttgagg gcaaacatta
     2281 gcaagtactg atataactcc ttgacctcct aaagataata aaggaagtat agtatcatca
     2341 ttaccagagt agatagcaaa gtcatctgga actaaactag ctatttctgc aacctgtcct
     2401 aggtctccac tagcttcttt tacagcaact atgttatcaa ttttagcaag ttcaactata
     2461 aggctaggac ttatatttac acaagttctt ccagggacat tgtaaagtat aattggaagt
     2521 ttaacactgt tagctattgt ttcaaaatga cgcttaagtc cagctttatt agctttattg
     2581 taataaggtg ttattattaa tagagcatct actcctaatt tttcagcttc ttgacttaag
     2641 ttaactgagt gcatagtatc attagaacca cttccagcta taacaggaac tcttttatta
     2701 actttttcaa caacatactt aatagtagca agttgttctt catcagtcat agtattagct
     2761 tcaccagtag taccacaaga tactatagca tcagtaccat tagctatttg gtattcaact
     2821 aattcaccta atttgtcaaa atcaactttg ttatcctttg taaatggtgt aactagagca
     2881 acagcagaac ctttaaatat catataaaat caatcccctc ttttttattt ttgtgtttta
     2941 tattacagtt acttctaatg cttgtttttg agttactatt aatattttac aaaattatat
     3001 atttatacaa gtttgtatat tatactaaat cgtatgataa agccatttca gctatttgaa
     3061 ttgcgttagt tgcagcacct tttcttatat tatcagcaac aacccaaaga tttacaccat
     3121 tatcaacact aaaatctctt cttattcttc caacaaatac ttcatctcta tcatcaaatt
     3181 ctacagcagt tggatattcg tttttagcag gattatcaac tactacaaca cctggagctt
     3241 cttcaagtgt ttttactaaa tcatctaact caaatggatt gttaaactca acatttatag
     3301 attcactatg accatttttt actggaactc ttacagtagt tgcagttatt tttaaatcgt
     3361 agttatcaag tattttcata gtttcattta ccattttcat ttcttcttta gtgtatccat
     3421 tttcagtgaa tgaatctata tgaggaagac agttgtaaga aatttgatga gggtagaatc
     3481 cagtaggatt accgttcatt cctttctcta aatcttcaac acctttaaca ccagaaccag
     3541 atacagcttg gtaagtagag taaacaactc tcttaatttt gtatttatca tcaagagctt
     3601 taagaggaac catagcttgt atagtagagc agttaggatt agctattata cccttatgat
     3661 tttttatggc ttctggatta acctcaggaa ctactaaagg cacatctgga ttcattctcc
     3721 attgactaga gttatctact actaagattc catttgaagc agctattgga gcatactttt
     3781 cactaatact tccaccagca gagaataatg ctatttgtat gcctctatca gtaaatgaag
     3841 tttcctttaa ttcttctact atatattctt taccacaaaa cattacttta gaaccagctg
     3901 atttagaaga agagaataaa aatagatttt ctattggaaa atttctttct tctaatactt
     3961 ttaaaaatgt tctacctacc attccagtag caccaactat tgctacattt acttttttca
     4021 tataaattca ccccaatttt aaattattaa aacattattt tattttagtt atacaagtaa
     4081 gatatgttaa tatttttata tatccaaaaa ctttaatatt atattaacaa ctttaattat
     4141 atacaaaaaa cgtacaaagg tatactttgt acgtctaatt tatcactcaa agtaaaccct
     4201 gtagctcatc acctacaaaa ataagtgaca gtattacaca tgttatgtgc aatcccagaa
     4261 aatattattg caagaaatat tttcttcggc tgtaaatcct ttttccaatc attaacacct
     4321 gccagctact attggatact cttagttaca gctacctcta ccctaggtta ataggatatt
     4381 aaaatttgat tattctaata ataatacata tttaagaaaa aatcaactta tttatataaa
     4441 tattgctaaa atttaaatcc aaaatttgtc aattcttgtt ttaacacatt aagattagtt
     4501 tcttccattt cagctagagg aagtcttaaa tcaccaacat taaaacctaa aatgttcatg
     4561 gcagttttaa caggaactgg atttacttct ataaataagg cagcaattaa agcatccata
     4621 tcaagttgta atttttttga gccttcaata tcaccttcaa agaatttagt tactaaatca
     4681 tgtgtttctt taggacatat gttagcaagt acagagataa caccacttcc acctaatgat
     4741 aatagtggta gtatagtatc atcattaccg gagtatatag caaagtcttt aggtactaat
     4801 ttagctattt ctgcaacttg agctaagtct ccacttgctt ccttcacagc aactatatta
     4861 tctattttag caagttcagc cacaacagat ggctttatat tcactttagt tcttcctggt
     4921 acgttgtata aaataattgg caacttaacg ctatttgcta ttgtttcaaa gtgaagttta
     4981 agacctttct cattagtctt attatagtaa ggagttatta ttaaaagacc atccacccct
     5041 aatttttcag cttcttgact catatgaaca gacaacatag tattgtttga accagtacct
     5101 gctataacag gtattctctt attaactttt tcaactgtat attttattac agcaaaaatt
     5161 tcagattcac tcatagtagt cgcctcacct gttgttccac aaacaactag tgcatctgtg
     5221 ccattctcaa tgtgatattc gattaattca cctaattttt caaagttgac attattatcc
     5281 tctgtaaatg gggtaactaa agcaacagca gaacctttaa ataacatata atcaaatctc
     5341 cttttttatc taaatttaat tttttaagta caataataat tatagtacaa attaattaat
     5401 tttaataggt atagttaata tcttaactgt ttaaataaga tatttatatt atattaatat
     5461 tagaaaaatt ttaaataaat gttttattct caaaatatgc atattaattt aataaaatat
     5521 accaaaatgg aaa
//
LOCUS       DAEOTL010000150         5412 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEOTL010000150 DAEOTL010000000
VERSION     DAEOTL010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5412
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.152"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            8..910
                     /locus_tag="KRH82_003760"
     CDS             8..910
                     /locus_tag="KRH82_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBG8657008.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGIVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            1522..2535
                     /locus_tag="KRH82_003761"
     CDS             1522..2535
                     /locus_tag="KRH82_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBG8657009.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKIFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            2887..3456
                     /locus_tag="KRH82_003762"
     CDS             2887..3456
                     /locus_tag="KRH82_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBG8657010.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(3792..5129)
                     /locus_tag="KRH82_003763"
     CDS             complement(3792..5129)
                     /locus_tag="KRH82_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBG8657011.1"
                     /translation="MGIYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
BASE COUNT         2022 a          532 c          874 g         1984 t
ORIGIN      
        1 tggaaatgtg ttgccacaag attattatgg attaatagtg attttaggtg ttattcttgg
       61 agttatgggg gcattttaca actggtttac tctatatgtg cagtctttat acaagaagat
      121 tcctaaaatt ggtacctttg gaaaactgtt gattccattt ataatggctg gtattcttgg
      181 gattgttatg cctgatgttc tggggagtgg acacaattta gttgaagaac ttacaagtca
      241 tgaatatatt tttggaatgg ttgttttgat ttttgttata cgttttatat tttcggctgt
      301 tagttttggg tcaggtgcac cagggggaat attttttcca ttgcttgttt taggagcatt
      361 tataggtgga atatttggta tggtaggtgt taaagttttt ggaatgaatc ccgattatgt
      421 aaataacttt gtgcttttgg ctatggcagg atattttaca gctattgtgc gtgccccttt
      481 gactggtatc atattaattt ttgaaatgac aggttctgtt agtcaaatgc tttcactatc
      541 agtaatttca attgtggcat atattgtggc tacacttatg aagtctaaac ctatttatga
      601 aagtcttctt gagaggttac ttgaaaaaaa tggagaacct gtacataaag agaggggcga
      661 aaagatacta gaccagttct ctgttatgtt tggctctcct gttgcgaaca aggcaattca
      721 ggatgtacag tggcctgaaa attgtctttt ggtagcaatt caaagaggtg gagaagaaat
      781 tattcctagg ggtaagacaa ttcttagacc aagtgatgta attgtgacta tgacagatga
      841 gagagatagt ggtgctgtgt atgataaaat ggaaaatttg tgtaaagaac atacggcaca
      901 tattttttag ggataatgat gaatgtttaa taatgataga atatttaatg aagatttgat
      961 taaaaaattg gtaatttgaa agagagttaa ggaattaata taagaaaatg aaaatgtgat
     1021 atcttagatg taaaagagtt tgaagaaaat aattgtatat atttgttaat gagattatat
     1081 ggactaatgg tatatttata ctgtgctaaa agttgcacta ttgtatgagg aatgggaata
     1141 aagggtttga aaaaataggt agaagatttt tcagatattc ttattgggat attttaatta
     1201 atatatttta attgcgatat tttgggaaga atagaattta tttataaatg aaaataatta
     1261 aaaggggtta aggttgtatt agcccctttt gcttatagag tttggaaatg gtatcttgat
     1321 agtagttgtt tcatgcttat tatattttat tacatatttt aaaattgacc ttattactcc
     1381 taaatcattg ttatatcaac ttttaaaaca ctttcaagac aatcgcctat tgaaaacaaa
     1441 gttaattaaa aacctacata tcagtttagt attcgtgtag atgattatat aaatataaaa
     1501 gtataagaaa ggtgagtatc tgtggttagt tcatttttaa atgatatctt tagaacaatt
     1561 ttagtaagtt gtatttttat agttatttta ttagtcttta gaataacttt atttaagatt
     1621 ttcagtaaaa aatttaatta ctatatatgg cttattgtga ttattaagct atcattacca
     1681 tttatgaatt atacttttat atttaatgag tcaaaatata atggtaatat taataagata
     1741 agtttaggca attttaatag tatttctatt gtatatagta ctgttttagt ctctgtttgg
     1801 attgctatta cgatatttta tttagtttat actttattga aatatattaa gcttaaaaat
     1861 atgataaatg atttgtctta tgatgttgag gatgataaga taaaaaatct ttatgaaaat
     1921 ttattaaaag agcttaagat aaataaaaaa atacggctta aatattcata tgaagttgaa
     1981 agtccagtat tttttaattc gtgtgtcatt ttaccaccat gtgattatac attgaaagag
     2041 ttaaactgga tatttaggca tgagttgatg cattttaaga gtaaagacct ttatattaag
     2101 tatttggtga tatttttaaa atgtgtttat tggtttaatc cttttgtgta tataatggag
     2161 aagtttatag atttggattg tgaattttat tgtgatgaaa gagttttgaa gaattgtacg
     2221 atagaagaga agcaggatta tgcattgaca ataattagtg caatgagaaa aggttcaaat
     2281 agttcaaata aatttgtggc tggattacat aaggagtcag atattaaaaa aagagtgttt
     2341 agtatgttta atgaaaagta cagaaatggt attttgatag cagttatttt atgtttatta
     2401 tcttctatta catattttaa aattgattta attactacta aatcaatatt ttatccactt
     2461 tcaaaacaaa cacctattga aaacagaact aattcaaaac ctacatatca gattaatgtt
     2521 tatatagata attaaaaaat acaaagttta acaagagatt aatataaata attttaataa
     2581 gtatctttca catatgttaa atttacttta attatattaa agccaatgaa ttattcttta
     2641 gaagctccaa tgccagtaaa tacaggtaaa gaaaaaatta ctacaattgt agattaaaaa
     2701 tgttctaata tttaaaaaaa tgcaaaagtg taagaagggt aaaaatctat tataatacat
     2761 taaaaactaa atttagaaaa atttacataa ttagaaaaat gatttgataa aaaataaagt
     2821 taaatattaa ctaagtaaat ttgaaaaaga aaaaatataa agtacaaatt taaaaggagg
     2881 taactaatga aaaagaagtt ggaagatatg actttagagg agttatggaa cttgtttcct
     2941 atatttttga ctactcacaa agaatgttgg aaaaattggt ttaaagaaga acaatataga
     3001 ctaactggaa tattgccaat gcaaaaaatt gttagaataa gtcatattgg aagtacttct
     3061 gtgagtacga tttatgccaa gcccattgtt gacatactga ttgagataat tcctgattat
     3121 aatatgaaag atattaaaga tttgattgag tcgaatggat atatttgtat gtctgagagc
     3181 agtagtaggc tttcacttaa taaagggtat acagtagatg gatttgaaga acgagttttt
     3241 catttgcata taaggtatgt aggtgataat gatgagttgt tttttagaga ttacttaatt
     3301 gaccacccag atgttgcaaa ggagtatgaa aaacttaagt tggacctttg gaagaagtat
     3361 gagcataatc gtgatgctta tacagatagt aaactagatt ttgttaggga gtttactgaa
     3421 aaggcaaagg tgttgtattc taatagatat aattagaaat aggtacaatt agatatttat
     3481 cttatatatt gtattatatt ttttaagaaa gtaattaata gaaaaagggc ttgtttcaaa
     3541 atggagagat aaatcccttt ttcattgttg aaaggataaa aatatatttg atttcatgta
     3601 aaaaagagtg cctcatcaac taaaaagttt attttgagac acacacattt ttactaaggt
     3661 aaataaaata tcacatttga ttaaatttta agttaatgaa tatatgtgta aatatttaat
     3721 tataagttat tataatttta catagtatca aacaatctaa tttgtattat ataagataat
     3781 ctaattttag actaaaataa tctaatataa agaaataaag aaaattcact ctcagtataa
     3841 gagatatcca attttccatt gtacttatta acaatttctc taatattctc aataccatat
     3901 ccgtgagaat tactatcttt tttatctgaa ataaatagtt cttgttttct attgatagga
     3961 tttaccttgt tgtttgtcaa taaatagcta aaatactcct tctcacaacg tgcctttaat
     4021 accacttttc tatttgacaa atcaggaatt ttcaaagatg cttctatagc gttatctaaa
     4081 gaatttgaaa aaatagtaca taaatctata ggttctatac ccaagtgatt gtctatatct
     4141 atattaaagt gcacatcaac accattttct tctaaacttg tatgacgaag atttaaaatt
     4201 gagttaagag cttggttttt gcaaaattgt tttccactaa gagtacctat acctattttt
     4261 aactgattaa aatacttttt agctccagca atatcttcaa tttctaaata cgattcaatc
     4321 atttgaaagt gattattcat atcatgtcgc attttgcgta tttgaatttg ttgattttct
     4381 agtaagttat agtatttttc ttttaggtga tttgcttgtt tttctatctt catctttaca
     4441 ttttcaatca atggctgtaa aagaagtatc acaccgatat ttgccagaat tgctgacaag
     4501 atgattagat aagtgccata aggtaagttg cctaagataa tattcttatt actacccata
     4561 gggattaaat tagtaggtgg cagaataata gcaattaata ttgataaaaa tgaagatata
     4621 cataccatat caataaaaat ccatatttta tttgataagt attgttttat attgaccaat
     4681 ctattcttta ggaaaatatg tattaaaaac caaaataata atttaattag agcagaaatt
     4741 atctggacta ttgaaagtat taaaatatac tcttttgagt gtataagttc ctcatatata
     4801 gggttgttta taaaaagaaa attaagccca attataatag gataaagtat catgacaact
     4861 gatattatag gaattaattt gcttttgcta catattataa gtagtataaa atatccaaat
     4921 agtgtaaaca aaatatttac ggggtcggaa agccatatta tcatttgact aataatagag
     4981 tagcccaaaa tcaatatgat tttgaaaatc caatgattcc taaagtctat aaaataggaa
     5041 gtcaacttat aaagaaaaaa ggctatgaaa atattgatta atattagaat aaaatttatg
     5101 cttgtagaga ttaaagaata aatgcccatt taatatacct ttctattaat taagattctg
     5161 gaaactaagt tttaaaaaat taaatcttaa aaattaaaat tctggaaatt agatttcaaa
     5221 gaattgattt tgaaaaataa aattctagaa attaagcttc aaaaaattga gttttaaaag
     5281 attgaaattt taaaaattaa gtttcaaaaa attaaatttg aaaaaaaact ctaaaaacta
     5341 agcttcaaaa aattgaattt tgaaagattg aaattctaga aactaagctt taaaaaatta
     5401 agtttgaaaa aa
//
LOCUS       DAEOTL010000151         5405 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEOTL010000151 DAEOTL010000000
VERSION     DAEOTL010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.153"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            180..911
                     /locus_tag="KRH82_003764"
     CDS             180..911
                     /locus_tag="KRH82_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657012.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
     gene            complement(1068..1274)
                     /locus_tag="KRH82_003765"
     CDS             complement(1068..1274)
                     /locus_tag="KRH82_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657013.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(1677..2072)
                     /locus_tag="KRH82_003766"
     CDS             complement(1677..2072)
                     /locus_tag="KRH82_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBG8657014.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            2213..2605
                     /locus_tag="KRH82_003767"
     CDS             2213..2605
                     /locus_tag="KRH82_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657015.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            complement(2705..3121)
                     /locus_tag="KRH82_003768"
     CDS             complement(2705..3121)
                     /locus_tag="KRH82_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBG8657016.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(3136..4047)
                     /locus_tag="KRH82_003769"
     CDS             complement(3136..4047)
                     /locus_tag="KRH82_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8657017.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            complement(4229..5251)
                     /gene="splB"
                     /locus_tag="KRH82_003770"
     CDS             complement(4229..5251)
                     /gene="splB"
                     /locus_tag="KRH82_003770"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBG8657018.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
BASE COUNT         1944 a          817 c          600 g         2044 t
ORIGIN      
        1 ttttctatct aaaaaatatt gatattaaat atctaataag aaaatttaat aagaaaaata
       61 tagattatat caaaaaaata ttctattata atctttagaa caaacagtag taaatgttat
      121 cttcataaac aaatttattt ttcacaagta caatacttat ttaaaaaagg aggtttaata
      181 tgttaagtaa aaaaaatgta agtttaatta ttttagtaat aattttaagt ttattaactg
      241 ctatatttat tttcaataat aaaaatacta acaataaatt gaaagaagtt actaagaata
      301 atgaagaaat agtacctaaa aacttagaag gtttaagtat agaacaatta atagagatta
      361 gagataaagc cattgataaa aatttagaag gtcttaggga atttggagaa gattcagtaa
      421 aaaaacgtaa agattcaatt ttaaactttg aatttggatt agtagctttt gttaacaaga
      481 attatagcaa cttaacagaa aaagagaaat taataagaca aattaatatt gttaactatg
      541 aaaactctat aaatgatata atggatcctt caggttcatt ctttgaatta gcaaatcaga
      601 attaccaagt gaatgagttt ctattaaaaa acggaaaaga ttataaagaa tggtcatatg
      661 aaggtctaga ttttctaatt gatcatctag aagaactgtg caaatttgtt gattttgatg
      721 taaaagatgt aatagatatt attgatccta caataaaaac agacctttca gaggaacaaa
      781 agaaatcttt gaatgataaa ttaaagaaaa tatcttcaag tgatacttta agtgaagaag
      841 ttaaaaagga gataaaaaac tgggaaaaca atttaaataa tttaaatatg aataaaaata
      901 attctaatta attttctcat aagaaaaatg cttatatcgt gataatgtga aatgtacata
      961 attataaaca aaaaaggggc tgtgacacta aaaaatagtg ctacgccctt ttttatttgt
     1021 aataatcatc aatacaaatt attttattat atgtaattat ttatgtctta accaatttta
     1081 tcgaaaataa cagtcttctc ttttaaagag atttttccta cttgatatcc atattcattt
     1141 aattcctttt tatatttcaa aaacgaatgg tctatctcta tcccagcaat atcttttatt
     1201 tcttcaaaag ttaatttaaa cgattgacta ttgtttttct taacatattc ccataaagaa
     1261 ctatatttac tcatcttata tcactccttt taaaatcata tcttatctat taatttatat
     1321 tctatcatta ttaatgtata aagtcatgct acttattatt tatatataaa aatatccaaa
     1381 taataagtag caatttttta tagtcataat atttttttca gattaaataa aaatcaatta
     1441 tagttaaaat attttttaaa agaaatctat cccattataa agtaaatttt aattatctta
     1501 tttctagtat gtaattattc aaaatagtat atcattattg aaatacacat ctaataacta
     1561 aaaattttta catattcatt atttaaaaat ctttttattg catttaaatt aaatctatca
     1621 acatttcagt aataacgttt tcttaatttt cactatggat gtcgattcaa ttataattaa
     1681 agctctacat caatcttttt accactcatt gaacaacaac taacttttgc cttatcaata
     1741 gagaatattt caaacttacc atctcctaca gagtacatct gacctaaact tggcattatt
     1801 tcaagtgcct tagcttgtgt ttcttttgat gtaacaaata ctgcttcacc taaaatacgt
     1861 agagtattaa ggttttggtc tatacaacaa agttcaacct ttggattaaa aataagttgc
     1921 ttaaacatat ccttttgatt agatgtgcaa aatgtaagtt taccattgta ttccataaca
     1981 aatcctaaag gacgcacatg tgcttgattg ttctcatcaa ctgttgctaa ataataaact
     2041 cgtgccttgt tcaaaaattc taatgctttc ataattctta cacccctttt aaatacttgt
     2101 attaaggatt atcctttgat ataattttaa tataaaatac agaaaaaaca agtatgcagt
     2161 tttttctgat aaagtataaa aaagatacta ctataactaa ggagtaatta aaatgagtat
     2221 aaatactgaa aaaaatataa ctaaaaacgt tgaagaatta acctgtccaa tccgttatgc
     2281 attagacatt gtcggtggta agtggaaatt acctattata tgtatgttag cagttgaaaa
     2341 tccaattaga tatagtagca taaaaagaaa attggatggc attacaaata ctatgctagc
     2401 tcaatcatta aaagatttag agtctactgg tattgttcat cgtaaacaat ataatgaaat
     2461 tcctccaaaa gttgaatata cattaacaag taaaggtaaa agtattgtgc ctattttaca
     2521 acaatttgct aattggggtg ctactaatat gcaagaaaaa aacacatgtg gacttagttg
     2581 caaagaatgt agaaagataa agtaaattta aatttactaa attattcata ttatagacta
     2641 tatattaatt tatctgattg aatataaaaa caggatgact tatatattca tcctgttcta
     2701 tatgttaagc tctaaattta attagttcaa gcatatcgtt taataccaat aaactatcta
     2761 cttgaatcat tagccattta cttccattaa aaaagtttac ctcattatat atttttttga
     2821 tataatcaca acaagtatta ataaataaat caacctctac tctattgctt tcacttacaa
     2881 taaccaaagc tttaaaataa ccttcttgtg gatataaagt acatagtgat ttacctcttt
     2941 ttttatattt tacattccaa cctctttgca ttgaacattt actgtattca agcttaggtt
     3001 ctacattata agtagaaacc aaagttttat ttaacttgtc ccataatgga ttattaataa
     3061 attcattaat ttgctcaaat gtaggtttag tatcttgaaa aaacgcatct tgccaattca
     3121 tattcatcat cctttctatt gttcaatagg aaccggaaca atccaatgtt ccagatatgc
     3181 tgcttcaggt gtagtggggt aatacatctc aattgcaaaa tcagtagttg ttaaattatg
     3241 tttcttcatc catctttcca taaatttatc tgctttaaaa acagctgaat taactaactc
     3301 attaaagttt tctgcctcaa atccacatac taaatattct ttagctggca actcaaaagt
     3361 actatatcct tctactgatg tacctgactc tacctctaca cctgccatat acatacaatt
     3421 tccttctttt gcatttccca tataaagagc agcaaattca tttccacctg gaatttgatt
     3481 tggtatatta tgtctttgac ttccaagttt catccataat tcctctacta ttgcaattcc
     3541 agttgtttca ccgcccacca actggcaaat aggtacttct atttctattc caacaaatgt
     3601 ccttggatta ctcaatgtct tacgattgac ttcaatcact atatcatctg caatcagtgg
     3661 aacaccttca tcaaccatag cataatttaa aattaattct ggcttaataa agtgattgag
     3721 ttttactgga tttgctctat atttttctgg agttaatcca tatgcttttt taaaggaacg
     3781 tgtaaatgtc tcatgactag caaatccaaa atttaaagct acatcaagta tacgattctt
     3841 atgttctgct aagtattcag aagctcttgc aagacgacga agctttatat actccattac
     3901 agtcttattt accaatcttt taaatagtct ttgatagtaa aatggtgata aatttgcttt
     3961 atttgctaat tcattaattg atatttcttc tgataaattt gcttctatta aatccaatgt
     4021 aatttgaata gactcccatg catgcatact ataactcctc ctgatatttt tgttactctt
     4081 atcctttata gtatcaaaac tagaaaaaat gttcttgata gatagtgccc tttttaattt
     4141 tcttatatga tagtgctaaa tctcattgct ttattataaa cataaaatat ataaaaataa
     4201 aatatagcaa atctttaggt aagatttgct atattatata ttttattaaa ctatttttaa
     4261 atactccatt tatttcctta agaaagaact ctttcatatc atctaattgt tctttatcat
     4321 acacgtactt accatatcca aattgaccgt atttaaactt tctatcttca ttttccattg
     4381 gcaatagtgt atctggataa atctctagta ttctattttt tgctttagtt gtatatctat
     4441 gagatataac ttcaaatata atttttttat caaaatcctt tggtaaagct tcttttatac
     4501 ttataatcag atttttatac tcttctttcc aaccttcata taaaaacaca ggtgctatta
     4561 tgaaaccaat ctgataacca gccctagcaa gttttacagc tgactctatt cttttatttg
     4621 cagaggctgt ataatgctca tgttcattta taattctagg agtattgata ctaaatcgta
     4681 tttctgtatg attattatgt tcagcatcca ataagctatc cacatcactg tatttagtaa
     4741 caaatctaaa tcttcctttt tcctctcttc caaaaaactc tattgttttc ttcaaagaat
     4801 tagtatatgg ctctactgga actgggtctg atgtagctgc cccttcaaat atggttacct
     4861 gtggctttct atcttcaata tatttttttg tctgttcaag tatttcatct acatttacaa
     4921 atacccttat aaatggttta tcacctaatt gtgtgttcaa ataacaatac tcacatcttc
     4981 ccatacatcc actgacaagt ggtagttgat aattagcaga aggtttacat gtttgaaact
     5041 tcagactttt tctaatccca actaccatag tctgcttccc acttctatat tgttcatata
     5101 gattttcacc tggaatatgt tctttaatcc tatttgatga tatattaatt atctctacat
     5161 ctttattatc tctaaattta ttgtatattt ttttacccac atcagtgtct aaagttcctt
     5221 tttcgaatat tattcttttg ggattaaaca tttatttcac ctctacttaa agtttttaaa
     5281 tcgaagaatt ttataaaata ttacttaatt aatcttccct tttttaaact cctttattta
     5341 ttagaaagta aaataaaagc ttaagacaaa tttattatat atataacttc tatacacaat
     5401 ttttt
//
LOCUS       DAEOTL010000152         5364 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEOTL010000152 DAEOTL010000000
VERSION     DAEOTL010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5364
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.154"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(75..758)
                     /locus_tag="KRH82_003771"
     CDS             complement(75..758)
                     /locus_tag="KRH82_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBG8657019.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(978..1568)
                     /gene="zapA"
                     /locus_tag="KRH82_003772"
     CDS             complement(978..1568)
                     /gene="zapA"
                     /locus_tag="KRH82_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBG8657020.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(1593..3986)
                     /locus_tag="KRH82_003773"
     CDS             complement(1593..3986)
                     /locus_tag="KRH82_003773"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBG8657021.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(4003..5022)
                     /gene="pheS"
                     /locus_tag="KRH82_003774"
     CDS             complement(4003..5022)
                     /gene="pheS"
                     /locus_tag="KRH82_003774"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBG8657022.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(5072..5306)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1621 a         1060 c          595 g         2088 t
ORIGIN      
        1 ttaatctata caatatttgc tatatataaa gtatatcaaa taacagcttc atttttttgt
       61 aaatttacag aaagttaatt ttcattaaat gaatcatctt tattgataaa cataattcca
      121 aagaccactg ccaaaataaa aaaacatatt agtattgatt tttccacgaa aatttttgta
      181 aaaaaagttc ctaaaatagc tccagatata aagaatataa taatagcata atactgtaaa
      241 ctctttttta tcataaaaat attcttagta tgtatataat gaaataaagt ttctgtagca
      301 cttcttaaat ttccagtaca cattgtcgtt gcaaaactat tcccatttac ttttctaaaa
      361 ctctctactt gcattgaaca aataaaagaa atagcaacat ttacaaacat attaaatctt
      421 cctctaggaa taaatgaaac aataagtatt gtaatcattt caattataat gataacctga
      481 cgccaatgaa tctttgtctt attatttgta aaatactttc ttatcttctc ggctataaat
      541 acacctaaca taaatgccaa aataggaatc aaataataaa atgattcctt tacattacct
      601 tctgctatat taagcccaaa caaaactata tttccagttt gtgcattagc aaagacttta
      661 cctcttacca cataagtata aatatccaaa aatcctcctg ttattgccaa caaagaacat
      721 aaaaagaatg attcagacat ctgactcttg cttgtcatat ataaacctct cgctttctaa
      781 tgatagatac aaaatcaaaa tcattttaga ttctattttt cattgatata aaaaaattat
      841 ttatatttaa atattgtcta tatttataca tcatttatat ttatttatat ttaaacatta
      901 tctatatcta tatagcattt atatttatac attaaaagaa gctgtctcaa aaaacaagag
      961 acagcaaatc ttttagttta ttccacattt tttgcatcat tatttaaccc tgtacatttt
     1021 aactgtaaat cataagcttt gttttgaaac tcagaagcta agttttcagc tatagtagct
     1081 ctttcatttg cttcttcaag ttgagtactt aactcctcaa tcttgttttt ataagcatct
     1141 aactctgctc tagaaccttc tgtcgtatta ctaagttcga atatttcttg ctttttattt
     1201 tctataatct caattaactc tttcatctta gtttcagctt cacgattttc tgcttctttt
     1261 tctgctatcg taagctttaa agatttgatt tctaattgaa gctcttcatt agatgctcca
     1321 accttcttac tcaattcttc attcgcttta atcaacttct cattctcatc tgaacattca
     1381 aataaaaggt ctgatatatt taatgcagtt aatatcgcag caactgataa gctcaatttc
     1441 gggttttgac gtgttatttt atccatttct ttgtctacaa aatcagcaat actaatcata
     1501 aacttctctg atttgtctcc aaccattgga tattcagcgc catggatttt aaccattact
     1561 ttgttcatcc taacctcccc cgacattagt tgttaatttg atcttaagtt agcatttaat
     1621 ttttcgctta attcacttaa tatcttatca tgcaccttag ctacatcttc atctgttaga
     1681 gttttatctt tacttctata agttattgaa tatgcaattg acttgtatcc agcttctatt
     1741 tgagaacctt tgtaaacatc aaataacttg tagctttcta ctaatccttg accattttcc
     1801 tttattatat cttctatttg ttttacaaat acatcatctt taacaataag agctatatct
     1861 cttgatgtag atggatattt tggtaatggc acataattct ttgttctatc agaattatca
     1921 aatacaaagt caatatctat ttcagcgaca taaactcttt gacctagatt gtagttttct
     1981 ataacatctg gatgcaattc acctaatgta cctacatatt tattattata cactatttta
     2041 gcacatctac cagggtggaa ggtagtatta ttatcttgag gttcaatttc ataaccttta
     2101 aatccgacat ttacaagtat agtttctata gttcctttta gtgcaaagaa gtcaacatct
     2161 ttaccataca tacctacaca cattctattt tcttccttag gtaattctga atcttgtggg
     2221 atgaatatat gtccacactc aaatgcagat acttcttcta ttttatgaga tacattagtt
     2281 gataaaacat ctaacatatt tggtattaaa gtagttctca ttacagaagt ttcttctcct
     2341 aatgggttaa gtaatttaac aaaatttctc tttgcattac cttctggtac tcttatctta
     2401 tctactccct tagggcttac aaatgaatat gttaatattt catttaatcc tacagcagtt
     2461 gaattatctt ttaaagcatc catgaatttt tgttttgaag ttttaattcc tgctgtcgta
     2521 tttccttcta attgtacaga aggtatattc tcaaatccat aaattctagc tatttcttcc
     2581 catacatcag cttcttgttc catatctgtt ctaaagcttg gtacatctat ttctaattta
     2641 tcattagcta ccaaattaca tttaaactct aatgattcta aaattcctac aaactgctcc
     2701 attggtacat ctacacctaa taggtggtta attctttgag gatttactac caatttttta
     2761 ggttctggtt tatttggata tacatctaca acacctttta aaacttttcc tgctcctaac
     2821 atttcaacaa gttgtgcagc tctatttgct gctatctctg caagattagg gtctaagtct
     2881 ttttcatttc ttgaagatgc ttctgaccta ataccaactt ttttagctgt cattcttatg
     2941 ttttctggtt tgaaattggc actttcaaaa agtacagtct tcgtattaga agttatttct
     3001 gagttagcac cacccattac accagctaaa ccaagtgatt tttctccatt tgttataact
     3061 agcatatctt tgtctaatgt tctctcaaca tcatctaatg ttacaagttt ctctccatct
     3121 ttagcatttc ttactactat tcttccagtc tctacttgat ttatatcaaa agcatgaagt
     3181 ggttgaccaa gctctaacat tacgaagttt gttatatcga ctatgttact tataggtctt
     3241 actcctgctt ctgtaagtct tctttgcatc caatatggag aaggttctat ttttacatct
     3301 gtaaccattc tagcaacata tcttctacat aaatctggat tatctatctc aactttgaaa
     3361 tctatctctt cgtcactttc ttttacttcg atttcaggat attttacttt tgttcctata
     3421 gttgcagctg cttctctagc tatacccatc atgcatttac aatcaggtct gtttgaagtt
     3481 aattcaaaat ctattaaagc atcttttaat cctaaaacat cttttatatc ttttcctaat
     3541 tcataagaat cttcgtggtc taaaatatat ataccacctc ttttatactc ctcaatgtaa
     3601 tgttcatcta tacctagttc agctgctgaa cacatcatac catctgataa ttcacctctg
     3661 aaatcagtct gtttgatttc aactcctcca ggtaacttag aaccatttac agctactgga
     3721 atataatctc cttctgatat atttgtagct cctgtaacta tttgaacaac tttatctcca
     3781 atatctactt tggttacaac caacttatca gcatttggat gttgttttat ttctaaaatc
     3841 tttccaacca atatattttc tatttcttca ccataataat ctattgtttc aactttagtt
     3901 cctgtcattg tcattttatc agcgaactct tttacatcca tgtctatatc aacatagtct
     3961 ctaagccatt ttaaagatac taacatctac ataccctcct aattaaaatt gatttaagaa
     4021 tctcatatca ttttcgaata ataatctaat atcatctatt tcgtatttaa gcattgcaag
     4081 tctttcaacc ccaactccaa atgcaaatcc actgtaaact tctgggtcta ttccacaatt
     4141 tctaagcaca tttggatgaa ccatacctga acctaatatt tctatccaac cttcatattt
     4201 acacattggg caacctttac caccacattt gaaacaagta acatcaacct ctgcacttgg
     4261 ttctgtaaat ggaaagttgt gaggtctaaa cttagttttg atatcagaac caaacaattt
     4321 ttcaacgaag atatccatag ttcctttaaa ttctgccata gtaacatctt ttccaacaac
     4381 aagcccttct atctgatgga acattggtga gtgtgtagca tctggcgagt ctgacctaaa
     4441 acatctacct ggtgcaatta cttttattgg taactcttga cttctcatag ttcttacttg
     4501 aactggagat gtttgagttc taagtaatac cccatcattg atatagaatg tatcgctcat
     4561 atctcttgat ggatggtctt taggagcgtt taatgcgtca aagttgtttt caacagtctc
     4621 aacttctggc ccttctgcta tagagaatcc cattccgata aatatatctg ttacttcatc
     4681 tataatttga gttattggat gcttcttccc aacctttaaa acttttcctg gttgagtaac
     4741 atctatcact tcctctttta attttctttc tttttcaata gcatttattt cttctttttt
     4801 ggaatttatg ctaagttcaa tgttttctct tacctcattg gcaaccttac caactactgg
     4861 tctttcttca gcagataatt tacccatttc tttaagtatg gcagttatct cacctttttt
     4921 tcctaagtac ttaactctta aactttctac actttctatg ctttgtgctt cttttatttc
     4981 agccaaagct gcttcacgta aagcaagtaa tttttcttgc acacatatca ccctttcgtt
     5041 tttttgtata aaaaaagccc ctcaatccct gtctagggac gaaaggctat agtttcgcgg
     5101 taccacccta gtagtttaac aatttaaaaa tcatcaaacc acctctaaca aacttaacgc
     5161 gtttttaacg tcaaagccta ctgtaaaatt tcagctctgt tactccagag ggaacttctc
     5221 atgacctctt agaaaacact cccagcctag gtgtttatct ctttactaag tttaatcaaa
     5281 atactttcct ctttcattgc atttacaata ttatattgtt tattttagta ttatatcatt
     5341 tccattcaaa ttatgtgact attt
//
LOCUS       DAEOTL010000153         5352 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEOTL010000153 DAEOTL010000000
VERSION     DAEOTL010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5352
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.155"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(204..1388)
                     /locus_tag="KRH82_003775"
     CDS             complement(204..1388)
                     /locus_tag="KRH82_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBG8657023.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            1761..4112
                     /locus_tag="KRH82_003776"
     CDS             1761..4112
                     /locus_tag="KRH82_003776"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBG8657024.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDNLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4134..4673
                     /gene="nrdG"
                     /locus_tag="KRH82_003777"
     CDS             4134..4673
                     /gene="nrdG"
                     /locus_tag="KRH82_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBG8657025.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2093 a          601 c          853 g         1805 t
ORIGIN      
        1 ttataataaa tttagaattt aacttatata gtttaatttg ataatttgat gaaaaaaata
       61 aaagacttac tgatttttaa atctataggt cttttatttt ttatctaaca tttaaattaa
      121 gttgttgaat atatcttata ttacttacct tatatattaa ttaccattaa tacattatat
      181 ctaattacta ttcatctaaa ttactatgcc attattttat atacaaattc ttttaattta
      241 tctaatccag ataagaaagt attttcactg caagcatagg atatacgaat atatttatcc
      301 ataccaaatg ctatgccagg aacaactgca acattatatt cttctaaaaa ttgattacaa
      361 aattctatag aaaaactatc tttatattca aatttctcag atactttaga aagatctata
      421 aatatataga atgcgccatt tggattcaca tatcctacat tatcaataga gtctagtttt
      481 gatttaatta aatctcttct tgatttatat gttttaacca tattgtctat gtcaattgag
      541 caatctttca aggctccata ggctatgtat tgtgctgtta gacttgggtg agatataaga
      601 tgtccttgta tagaactcat tgctttagca atcgttttat tagatgcagt atatcctaat
      661 cttaatccag tcattgcagc tgacttagaa aaaccattta tagttattgt tatatcttta
      721 gcttcttcgc ttaatgatgc aattgatgta aattcaccag tgtagcatat tttttcatat
      781 atttcatctg ctaaaatata tattttattt tgtatgcata catctactat ttctattaat
      841 tcatcttttg tataaacact accagtagga tttgaaggat tgtttattac aagaattttt
      901 gttttatctg ttatagattt ttcaagttct tcttttgtta acttaaatcc attttctttt
      961 ttagtatcaa taaaaactgg aacagcatta actaacttaa tcatttcagg ataactaacc
     1021 caataaggct ttggtaataa gacttcatct ccttcgtctg ttaaagctag taaagtattt
     1081 gttattgagt tttttgctcc acttgataca actatttcgt ctattgaata gttacagtta
     1141 ttttcttcaa taagtttttt acagatttcc tctctaagta tttttaatcc tggaactaaa
     1201 tcatatttag tgtaatcttt atttaaagaa tcaataccat aagattttgc gttattaggt
     1261 acattaaaat cgggttctcc tatactaaga tttattactt taactccatt actttccatt
     1321 tctttaactt tagaactaat acctattgtg taggatggtg ttataaagtt tagtcttttt
     1381 gataacataa aatgcctcct tttaaattat tatttatatt atacgacaaa tttaaagaat
     1441 ttacataagg aaatttgtag atatatacat taatatatat aatagcctac actttttgcc
     1501 taaaattagt gtaaaaaaaa gagaaaaaaa ttttaacttt caaagttgtt agaaacgctg
     1561 ctgttcaaaa tatccacata gtatttgcaa tgatttgcgc aagtttgact attatgtaca
     1621 aatttggtaa tcttaatata gcaattatta agataatccc tttaacttag ttgaagggga
     1681 tttttttaga cttaacatac tacatatagt ggtatgggga ttaataaaat acaatatata
     1741 gtaacaggag gtttttttaa ttggttgaat tcgtaaaaaa aagagatgga agagtaattc
     1801 catttaatga agatagaata acaagagcta tatttttagc agcaacgaat gttgcagaaa
     1861 gagaaggaat agtacctgat tataaattat ctgagcaatt aactcaagaa gtaataaagt
     1921 ttttaaatca taaatactca gaatcagttc caagtgttga agatatacaa gattctgtag
     1981 ttaaggttct tatagaaact ggccatgcaa aaactagtga agaatatata atatacagaa
     2041 ctgaaagaag tagaataaga aattcaaaaa caaggttgat gaaggcaata gaggaaatta
     2101 cctttgaaga tgcagaagat gctgatataa aaagagaaaa tgcaaatatt aatggtaata
     2161 cagcaatggg aactatgtta caatatggaa gcactgtatc taaagaattt tgtaaaacac
     2221 atatattaaa accagagcat tcttttgctc atgataatgg agatatacac atacatgata
     2281 tggatttttt aaatatggga acattaactt gttgtcaaat agatgttaaa aaactattca
     2341 atggtggatt ttcaacagga catggctttt taagagagcc acaagatata ataagttatg
     2401 gtgcattagc tgcaattgct atacaaagca atcaaaacga tcaacatgga ggtcaaagta
     2461 taccattttt cgattatgga ttggctgaag gtgtatataa gacatttaag aaattctaca
     2521 taggaaattt agctaaagca ttgaagttat ttaaaggaat tgaaaataat gatgtgataa
     2581 agaacatagt atataataca gagaaagaaa caaatcaaaa agttggtctt aagagagatg
     2641 aattgtatct aaacttagaa aaagagaaat taatacagac ttttgatata gatgatgaac
     2701 ttgtaaataa gatgcaaaac tttgcatttg aagaatcgta tagagaaact gataaaaaaa
     2761 catatcaatc tatggaagca tttatacaca atctaaacac aatgcactct agagcaggtg
     2821 cacaggtacc attttcaagt gtaaacttcg gaacagatac ttctgaagaa ggaagaatgg
     2881 taactaagaa tcttctatta tctcaagaaa gaggtttagg taatggagag acaccaattt
     2941 ttccaatttt aatatttaag gtcaaagaag gcataaattt aaatcctgaa gaccctaatt
     3001 atgatttatt taaattatca tgcagagtat cagctaaaag actattccct aattttagct
     3061 ttttagatgc gccttttaat gcaaaatatt ataaaaaagg tgaaccagat acagaggcta
     3121 catatatggg ttgtagaaca agagtactta gtaatgtgtg tggttcagaa acagttagtg
     3181 gtagaggaaa catatctttt actacagtaa atttaccaag attgggtata aaacatggta
     3241 ttataaataa tgaaaaggct aatttagatg gtttctttga agaattagat gagaagataa
     3301 acttaattat agaacaatta ttggagcgcc ttgaggttca aggaaataaa aagatgaaga
     3361 attttccatt cttaatgggg caaggtgtat ggaaaggttc tgataattta ggaccagaag
     3421 atacactaaa agaagtaata aaacaaggaa cattgacaat tggatttata ggtttagcag
     3481 agtgccttat tgctcttata ggtaaacatc atggagaaag taaagaagct caagaattag
     3541 gattaaaaat agtgtcacat atgagacata aaatggatga agcaacggac aaatataaat
     3601 taaatttctc cttaatgggt actccagcag aaggtctttc aggtaggttt actaaaatag
     3661 ataaaaaagt ttatggagaa attaaaggta tcacagataa agaatattat actaattcat
     3721 tccatgtacc agtttattac aatataagtg catatgataa aattgagata gaagctccat
     3781 accatgaatt gactaatgca ggtcatataa catatgtaga gttagatgga gatccatctg
     3841 ataatttaga agcttttgaa actgttataa aagctatgaa agatttgggt ataggatatg
     3901 gaagtataaa tcatcctgta gatagagacc caatatgcgg tttttcaggt gtaataacaa
     3961 gtaatatatg ccctgtatgt ggaagaaatg aagatgaaag tgacatcaaa ttcgaaagaa
     4021 taagaagaat aacaggatac ttagttggta cagttgatag atttaataat gctaaaaaag
     4081 cagaagtaag agatagagta aaacatagat agttttattt gggggaataa gttatgaaaa
     4141 taagaatgtc atctactata agttatgaca gcatagttga tggaccagga ttaagaatgg
     4201 taatatggac tcaaggatgt attcataatt gtaaagagtg ccataatcct cagacacatg
     4261 atttatgtgg aggattttat atggatacag aagaaattat aaataaagtc aaatcattga
     4321 aattacaaaa aggcattacg ctatcaggag gagaaccatt tttacaacca gaaccattag
     4381 aagaaatagc aagagaagct aaaataaatg ggttagatgt atggtcatat actggattta
     4441 cgtttgaaca actgttagat aaaaaaaata gagcgtattt taaaaattta aatttactaa
     4501 agcaaattga tattttagtg gatggaaaat ttatagctga aaaaaaagat ataagcttaa
     4561 agtttagagg gtcatcaaat caaaggataa ttgatgttca aaaaagtttg aaatataaaa
     4621 aagtgttttt ggttgagcaa tatatgaagg atgatttatc tatagcagaa taaaatataa
     4681 ataaacagga ttaaatatat gcatatattt aatcctgttt attttcatat aatatttcaa
     4741 gcttgtataa tgtaacaatt aaaccaaaag actcattgta tatttgaaat taagtttttt
     4801 atagtttata ggtgttttat gtggattacg aatgatatag tatcgataca ttatttaata
     4861 gattcttatg ccaagaaaca attaatttat agaaattctt aattgttaca atataaatat
     4921 ctagataagt tataagatac tgataaataa tttataaagt ttattaatct aatattgtgt
     4981 gtgaatatta agtggtcaag tagtctaaaa aatgaaaaag atttaaaaaa gtgttttaac
     5041 taaacacata agtgttaaat tcatgtataa gtataggtta gatacataag aaataattat
     5101 gtaatatcta tctttgtaaa aaaatattaa attttgtaat ttgtggataa atatgtttat
     5161 aatgtggata atatttaatg taataagtta aagcaatatg aatcaactgt ttataatgtg
     5221 gataatatta taaatgtatg aataattgca gtatttaaaa acaaaaaaag ttaaaaaagt
     5281 tgttgactct aaaagaaaaa gttggtatag taatacttgt cctcaagaaa agggcaaaca
     5341 aataaagcac aa
//
LOCUS       DAEOTL010000154         5322 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEOTL010000154 DAEOTL010000000
VERSION     DAEOTL010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5322
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.156"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            268..1731
                     /locus_tag="KRH82_003778"
     CDS             268..1731
                     /locus_tag="KRH82_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBG8657026.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKLFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKKIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            1787..2923
                     /locus_tag="KRH82_003779"
     CDS             1787..2923
                     /locus_tag="KRH82_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBG8657027.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            3159..4274
                     /locus_tag="KRH82_003780"
     CDS             3159..4274
                     /locus_tag="KRH82_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBG8657028.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTIMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAVIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLDPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLFCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            4426..5295
                     /locus_tag="KRH82_003781"
     CDS             4426..5295
                     /locus_tag="KRH82_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBG8657029.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGNLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
BASE COUNT         2047 a          547 c          991 g         1737 t
ORIGIN      
        1 tttcaggctt ttcattatat gtattccaat ttatattgtt tgattattat tcaaacacac
       61 gtcgttaaaa attttataaa tttatgttta gatatgatta atactcttga ttttagaaat
      121 aaatatttgt agattgtaga ttaaagataa tataaataaa tagaaggtag attttttaga
      181 tatattaata taaagattat ataaaatatt gaaatatagc tgtttaaatt attgtctata
      241 aatataaaat gaatggtggt gagttaagtg accgatttag ttaacaccat taatggaatt
      301 gtttggtcac ccgtattagt tgcaatgtgt ttgtgtatag gattatattt ttcattgaaa
      361 ttaaaacttt ttcaaataag agatgtaaaa gaaatgttta ctctcttgct tgaaggagat
      421 agttctcatg ttggtatatc atcatttcaa ggttttgcta catctatggc tggaagaata
      481 gggactggaa atatagctgg tgtagctgta gcaatagcaa tgggaggtcc aggagcatta
      541 gtatggatgt gtataatggc tacattaggt tcagcaactg catttgtaga atctacttta
      601 gctcaaatat ataaagatga gcatgatggg cagtatagag gaggacctcc atattatttt
      661 gaaaaaggtc ttgggtggaa aaagtgttca gttttatttt caatagttgc aataataagt
      721 tatacatttt ttatgcctgg tacacaatca aacactttat atctagcaat gaatcaagca
      781 tttggatttt caaaaatgac aatagcagta gcatcttcta ttgcattagc gataataatt
      841 tttggaggaa ttaaaaagat tggtttattt gctgaaaaag tagtacctat aatgggtgga
      901 gcatacctta ttatgacatt agtaataatt ataacaaata ttagtttagt tccagaggct
      961 attgtaacaa tgtttaaatc tgcatttgga tttggttcag tttttggagg aatgctaggt
     1021 tcagcaatat cttggggagt aaaaagaggt atatactcaa atgaagcagg agaaggttct
     1081 gggacttatg gtgcggcagc agcagaagta agtcatccag ccaaacaagg attagttcaa
     1141 gcattttctg tttatgtaga cacattatta atatgtatgg ctacaggtat tatgattgta
     1201 ataacaggaa tgtataatgt tacaggtgtt tgcacagcac taccaggtgt agaaccggga
     1261 ccacaatatg tacagagtgc aataaataca ttacatccac aattaggtga tatttttata
     1321 gcaatagttt tattattatt tacatttaca actttattag ccttctcata tatgatggag
     1381 actaatgtat cttacttagt aactagaatt aaagcagaaa aacatgaaaa gtacataatt
     1441 aatgtctgta gatttatgct tatagcatgt gcagcaatgt gttgttttat agaaccactt
     1501 acaagctggg cattaggtga tatatgtata ggtgtattaa catatataaa tttaattgcc
     1561 atctttacac taaaaaaacc agctataaag gcatattatg attatataag acagaagaag
     1621 atgggaataa aaaggagtga tagaactttt aaccctatag agttagatat aagaaatgct
     1681 gagttttggg aaaatagata cttaaaagag gataagcatg agttaaatta aagttataat
     1741 aaaatataaa aattactaaa taaatttagt gggaggtaag attggtatga aagaaagaat
     1801 aatacaagtg gctgattcaa agaaagaaaa aattctaggg ctatgtcaat ctttatatga
     1861 tgaaccagaa attgctttgc aagaatataa atctgctaaa aaaatatcag aatttctaag
     1921 agaagagggt tttgatgttg aggaaaactt ggcaggtatg gctacagctt ttaaagcaac
     1981 caagaaaaat ggagatggtc ctaaaatagc atttatagca gaatatgatg ctcttccagg
     2041 caatggacat gcatgtggac atcatttaat tgcatctatg ggagttggag ctggaatagc
     2101 tctttcaagt atactggata cttacaaggg agaagtaagt ataattggaa cacctgctga
     2161 agaaactgga gatggaaagc cttacttgat agaacatggt gtatttgatg gctatgatgc
     2221 agcaatgatg atacatccaa attcaaaaac ttgtgtaaca cctgaaatta tagcaatagg
     2281 aggtctagat ttcatattta ctggaaaagc atctcatgca ggagctaagc catataacgg
     2341 aataaatgct ttagatgcag tagtactact atataataat ataaatgcac taagacaaca
     2401 attagtagat ggaacgagaa tacatggtat tatattagaa gcaggaactg ctgcaaatgt
     2461 aatacctgat atgggaaaag taagattaga gataagggca aaagaacaaa attactttga
     2521 tgaagtagta gaaaaagtga aaaattgtgc tagaggtgct gcaatagcca ctggatgtga
     2581 acttgaattt tatcactttg aaccaacttg ccaaggatta aatgaaaata aagttttggt
     2641 agatatattt acaaagatta tggaggaatt tggaatatat gaagatgaac aagtaatgtt
     2701 aggttcaaca gatatgggaa atttaagtca aataatgcca tgtatacatc ctttgatgaa
     2761 gttttctgaa aatggagaag aactacatac aaaagaattt ttggaggctt ctataaattc
     2821 atatgcaaaa gatagagtaa ttgatggtat aaaaatatta gctttaacag gatttaattt
     2881 atttgaaaat ccagaattat tgaaaaaaat gaaggaagag tagaacttag actattttta
     2941 attatactct ttaaaataag aagagtgtct caaaatgaac tttttagttt atgagacact
     3001 cttttttgta tgaaattaaa tatattttta ttattttaaa catgaaaaag aggcttatct
     3061 gtttttatat gacctttttt aacttgtagc acaaaatatc atgaatgatt acaattcgaa
     3121 tgataaaatc gattataaga tatataggag gggtacatat ggaaacttta gaagtaagaa
     3181 atattgaatt gagtggtaca aattatgaga taggatacag actaggagaa ttggttgcta
     3241 atatgccaga gataatagaa ggtcagatta ataaatctaa tctggtaagc aaaaaagaag
     3301 aaaaagagat gatagagttg tttgataaat attgtccagg tcttaatgaa gaattgcaag
     3361 gttttgctga tgcaattcaa gtgaattgta atcaaatttt atattatact atgacttatc
     3421 ttaaaccagg ttgtagtcaa gttgcattag caccagaatt aactgaaaat gggcatgtac
     3481 tatttgcacg taatttcgat ttctcacaca atatggagga ttttgtttta tgtaaaacta
     3541 aggtaaatgg aaaatatgca catataggta ctaccattat gcaatttgga agaggtgaag
     3601 gtatgaatga atgtggctta ggtgtaagtc agtcatcatg tggtattcct gtaggcaatt
     3661 cagatggttt aagaaaacca gcaattgtag gtttacagtt ttgggctgtt attagatatt
     3721 tgttagaaaa ttgcaaagat gtagatgaag cattagaata tttaaaagat atgccaattg
     3781 catacaatat taatttattg cttgcagata agtctggaaa cattgcactt gtggagactt
     3841 tagatgggaa aaaagaagta aatataatca acagtttaga aagtaaaaga gaatattttt
     3901 tacactctac taatcataca catattgata aacttcataa attagatcca caatcaatga
     3961 aaaattctat tcatagatat aaattaatta aagaatatat aaataagtct aaaaaaattg
     4021 gagagaaaga gttaatgaat ttattgtctt caaaatatcc aaatggctta ttttgtaatt
     4081 actataatga tttttttgga actttaaaaa gtatagttat ggatttaaat ataggaaagt
     4141 ttaatatttt atggggtgga ctagagaata aatgggagag ctactattta aaaaatgaca
     4201 ttaaatctat aacacagagg ataaacataa atattgaaaa agcaccatct gacttttttg
     4261 atttcattga ataaaaaatg tattcaatta ttctaaataa ttaggatata taaatcaact
     4321 aaaagttttt atttatcgta ttgaattagt tataatattt tagtatagta aaaaatagtg
     4381 ctattttaca tatttaaaga gtttaagtaa aagagaggtg ccatattgga ttacttaaag
     4441 tattttgaaa aagctgtaat gtatattgag aataatttac atgaaaatat aactgtaaat
     4501 gatgtggcaa aagaaactgg atattcttat tatcatttaa cacgcttatt taagtctatg
     4561 tttggtgaga gtgtaggaag ttatataaaa aaaagacgat tagtaagtag tacaaaagaa
     4621 cttttatata gtgataaaaa agtgatagat atagctattg gtagtggatt tgaatcttca
     4681 gaagcattta gcagagcatt taaatctata tacaaggtta gccctataga atatagaaaa
     4741 aatagaattg atgtatttgt tggtaaaaag aaaaaattag agttagattt tatgagacat
     4801 cttgttggaa atataacgat taaaccagtt ataaaagaaa tagaaaaaat aaaggtaata
     4861 ggtataaagg ataaagtaat tttagaaaat aattcattac ctgacttgtg ggagaaattc
     4921 agaaaagtac atcatattgt cccaaatact ttgccatcaa agagagtttt tggaatctgt
     4981 gaagcaatct ctgaaataca cctagttagt gaaagtatgg aatttaatga gataatagga
     5041 cttgaagtta atagttatga tgtgattcca aattcatttg tttcaaaaac tattaaggaa
     5101 ggaaagtatg ctatatttac tcatactggt aacttagata atttagacaa aacttatgaa
     5161 tatatatggg gtacttggtt tttaagttca aaagaagaac ttgatataag agatgatttt
     5221 gaagtatatg atgaacgatt tttaggtcct agtaatgtga actcacaaat tgatatttat
     5281 atacctataa aataatctat aagaaaacta aaaaataatt tg
//
LOCUS       DAEOTL010000155         5216 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEOTL010000155 DAEOTL010000000
VERSION     DAEOTL010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5216
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.157"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            60..1064
                     /locus_tag="KRH82_003782"
     CDS             60..1064
                     /locus_tag="KRH82_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8657030.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGIKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            1190..2302
                     /locus_tag="KRH82_003783"
     CDS             1190..2302
                     /locus_tag="KRH82_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBG8657031.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAES
                     KQNESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            2791..3552
                     /locus_tag="KRH82_003784"
     CDS             2791..3552
                     /locus_tag="KRH82_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657032.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            3555..4373
                     /locus_tag="KRH82_003785"
     CDS             3555..4373
                     /locus_tag="KRH82_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBG8657033.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            4553..5155
                     /locus_tag="KRH82_003786"
     CDS             4553..5155
                     /locus_tag="KRH82_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBG8657034.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIKPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         2186 a          480 c          933 g         1617 t
ORIGIN      
        1 taggatgtaa aaataaatag gatataaaaa tatcgtaaat gtatgaggag tgaaatttaa
       61 tgcgtttcaa aagaatattg atattgatgt taactgtagc aatgatagct ggaatgttgg
      121 ttgggtgtgc taataaccca agcaataatc ctagctctag caaagataat aaaagtgata
      181 taagcgataa aagtaattca aaaaaatctg tatcaatgat actagatatt gaaggaacaa
      241 ataatgaagc tatgaataat tcagctttat tagcattaaa caatgctcaa aagaaactta
      301 atatagatac aaacaaagtg gaatcagatg attcctcaac tttttctaat agtatagata
      361 ttttatgtaa tgacaattac gatttaatta tagctgtagg agctagattt gcaaaaccat
      421 tggagatggt agccaagaaa tatccaaagc aacaatttgc aattatagac tatgagtatg
      481 acaagcaacc ttctaatata acttcaattt cttatgaaga taataaatct ggatatctag
      541 ctggattaat tgctggaaaa atgactgaaa gcgataaggt tggttttata ggaggaataa
      601 agagctctag tagggataaa tttgaatcag gttttagaga gggtgttaaa ttttctaata
      661 gtagtataaa ggatatttca gttgagtatg cagatgtttt taaagatagc aaatcagtag
      721 aatctatagc taaaaaaatg atggataatg gagtggatat tattttttct actactgaag
      781 atgattcaaa agctgtaata gatgcagtaa gggcaaaaaa taaaaaagtt atagcaacga
      841 ataaagacca acatgagtta gctccagaaa atgttataag ttctattgta aaagattttg
      901 agaatcctac ttataatctg atacaaagtt ttgtaaaagg aaattataaa ggcggaaaag
      961 ttatagaaaa cacagttaag tctggaagta ctgggcttgc ccaaaatagt tctcaaaata
     1021 ttcctccaga tgtgttagaa tatgttaata agaacaataa ataatctact ataatatcca
     1081 agaatactta tgactttagt tatgaggtga attggatgtt ataatagaca tatatagaaa
     1141 gacatatgca gaggtaggtc agacctatct aaatcaggga gtgaattttg tgaaaataaa
     1201 aaggatattg atggcttgct ttgtagtagt ttttacaatt tttatattag ctatatgtaa
     1261 ttttgatttt ggatttgata aagtaaataa gaataattct aatatagata gtgctgaatc
     1321 gaaacagaat gagtctaaaa gtttgccaac ttcagcagaa aaggataaat caaatagcaa
     1381 aagtaagaat aaagaagatg acacagaaga tgattcatat gtaagaaaaa ctattggagt
     1441 attgttagat accgaaaact taaataacga atcatataat aacaatgtac tatcagcctt
     1501 aaaaagggct gacgaagatt ttgatgttag gataaaactt gaaaaaccaa agacttctaa
     1561 aagttttaaa gagagtatag aaaaactgca taagtatgaa ccagatttga taatagcagt
     1621 tggagccaga tttgcagagc caattaaaga agctgctact aaatatccca aacagcaatt
     1681 tgcaatagtt gactatactt ataaagttca gccagctaat gtaatttctg tatcatttca
     1741 agataatgtt actggatatt tagcaggact tattgcaggt aaaatgactg atactgggaa
     1801 agtcggtttt ataggaggag ttgagggttc tagtagagat aagtatgaat ctggatttag
     1861 aaaggggctt aaaacttcaa ataaagatgc tgagttacta gttaagtatt caaatatatt
     1921 tgaaaaccct gaatcagcta gaactattgc aaaggaaatg agagattctg atagagatgt
     1981 tgtattttca gctacagaag atgatagtaa aagagctatt caggtagcaa gagaaaatgg
     2041 tggtaaagtt atagctatta ataaagacca atacgatatg gctccagata atgtaataag
     2101 ttcaattata aaagatgtag aacaacctgt atatgaactg ataaagaacg ttgcaaaaga
     2161 tggttttaag ggaagtaaag taatggaatt taaaataaaa gatggagaac ttggcttgac
     2221 ttcaaagagc agtagaaata taccaccaga tgttttggaa tacataaaaa aagagtataa
     2281 caaagtgaaa gatacatatt aattattgag tagaagatta taaaaatata ctgattaagt
     2341 ttagattggt gataaaagga tatatttatt aaatttgtgc taactgtaca aaatatattg
     2401 attaagttta gattagtgat aaaaagatat atttattaaa tttgtgttaa cagtatggaa
     2461 tatactgatt aagtttagat tggtgataaa aggatatatt tattaaattt agtctaactg
     2521 tacaaaatat attgattgag tttagattag caataaaaag atatatttat taaatttgtg
     2581 ctaactgtac aaaatatatt gattaagttt agattagtga taaaaggata tatttattaa
     2641 atttgtgcta actgtacaaa actatactaa ttaagcttag attaactata taaaattata
     2701 acaataagtg tgtgggcaga aaaattctgc tacacacttt atttatattc acataaaaaa
     2761 tttatcaaaa aaaagaaaaa ggagtaaaaa atggaattta caagagaacc atttatacta
     2821 gatgacgatt tgtgtctagc tttggtggac aaaagaatta gttatctaat ggaaaatgaa
     2881 ttaaaattaa gaaatataga gataataaaa acaatagaat gtaaagaatt atatgaaagc
     2941 ataaaatatc acccggatat atgtatttgt aatttaggaa aaggagatat aattgttgcg
     3001 ccgaatgtat ataatcaata caaagagtta ttaagtagat ataaatttaa tataattaag
     3061 ggagaagcta atttattaaa tagataccct tatgatatac cttacaatat tgcgatagtt
     3121 ggtgactatg ctatacacaa ttttaagtat actgacaaag caatattaga ttatattgaa
     3181 aataataaac ttaaaaagat aaatatagag cagggctatt ctaaatgctc aatctgtata
     3241 gtagatagaa cgtctataat aacatcagat aaaggtattt ggaaaagtat gaagaataca
     3301 gaaatagagt gtttattgat agaaaaaggt cacataaatt tatttgagat gaattatgga
     3361 tttataggtg gatgtacagg gttgatttct aaggataaac tagctttttg tggagatgtt
     3421 aaaaaacatc ctgactatga acgtataaaa agttttgtag aaagtaaaaa caaggagata
     3481 gttacactta gctgtgaaaa tttactagat ataggttcta tagttcctct catgacaaga
     3541 aaggagcgat aactttggtt gagaaggata atatttcttc catgaaattt ttgaggaata
     3601 ataatgtaaa cgatagatta atatatacga atgacattgt agaagtagtg atagattctg
     3661 caaagcaaga agtgttaaat aaaaaaatac ttaatggtac taaagctgaa caaagagctt
     3721 taaatattga tgagatatca acggaaataa ctagtatgat aataagtata atgaaagaga
     3781 aacttttgaa agaatacatt ctaaaatgct atgggcgtac atatcctgaa gataaaaata
     3841 atatatacat atattcactg aacatatttg ctaaaaaaga gatttttatg agagaaacag
     3901 tatttactag ggtgagaaat tatatagaag aaaatgattt tataaatgta gaaggtttta
     3961 ttagatttag aatgagagaa tttatgaaat atatttctgc tataggtgat attgcagttg
     4021 aggagtattt aataaagaaa gaccaagatg aatttataag agttttaaaa tactttatag
     4081 atactcaaga agaaaagatt gatttgctta aagttcatat aatggaagat aatacatttg
     4141 ttttatacga taaaaatgga aataagatag acagtataga tgatgaagaa attataaata
     4201 tggtaataag agaaaattta aattatgagg actttttaat aagtacctta ttaactctat
     4261 gtcccaaaaa aatagaaata ttggatttgt taaataataa ttgctcaaag gaaattatag
     4321 atactgtaga agcaattttt gaaaataaag ttagtataat tatggaaaac tagaatctaa
     4381 gcatataaaa gctatccata taaaattaaa aaaattcttt ttaaatcgac acaaaagact
     4441 tataattgta tataaagcta tagtataact agaattatta agtataaaga atatctactt
     4501 gattaataca atatagctgg caaatataca attgataagg agtaatttta taatggataa
     4561 tttaattagg atactgatat tagctgttat tggtggattt ataggttatg ttacgaatgt
     4621 agttgctata agactgatat ttagaccaat aaagcctatt aaaataccta ttttaaatat
     4681 agaaatagta ggtcttatac caaagagaag agcagaaata gcagcaaatg taggagaaat
     4741 aattcaagaa gaatttcttt ctatggacga aatacttgca aatatcatta ctgacgaaga
     4801 taaggaagaa gttgtaagat acataaaagc aagggtaaaa attataatac atgagaaagt
     4861 ttcatttatc ccgagtggta taaaaaacat gatacaagat tatctaggag agataattga
     4921 gtctgaagtt aagcaaagta tagatgaatt gagtaaaaat ataataaata aagcaaatga
     4981 acgtatagat atacaaaaaa tggtcgaaga taagattaat gaactagatt tatatgaatt
     5041 ggaagagata ataataagaa tagctaagaa agaattaaaa catatagagt ttttggggct
     5101 tgtcttaggg tttttaatag gtatagctca agggttaatt actatgttta tttaaatata
     5161 tgagaagtag catttattta agtactaatt atatttacct atttgagtga attact
//
LOCUS       DAEOTL010000156         5181 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEOTL010000156 DAEOTL010000000
VERSION     DAEOTL010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5181
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.158"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            776..1006
                     /locus_tag="KRH82_003787"
     CDS             776..1006
                     /locus_tag="KRH82_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8657035.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            999..1580
                     /locus_tag="KRH82_003788"
     CDS             999..1580
                     /locus_tag="KRH82_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBG8657036.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(2158..2835)
                     /locus_tag="KRH82_003789"
     CDS             complement(2158..2835)
                     /locus_tag="KRH82_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBG8657037.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAIQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(3024..4388)
                     /locus_tag="KRH82_003790"
     CDS             complement(3024..4388)
                     /locus_tag="KRH82_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBG8657038.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLIVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            4516..5037
                     /locus_tag="KRH82_003791"
     CDS             4516..5037
                     /locus_tag="KRH82_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBG8657039.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         1960 a          670 c          837 g         1714 t
ORIGIN      
        1 gtttaacttg tgattaatag agtagggtgt aactaaagat aaacttcaat atgagtttaa
       61 cttgtgatta atagagtaag gtgcaactaa agataaactt caatatgagc ttaacctatg
      121 attaatagag taagagtgta actaaagata aacttcaata tgggtttaac ttgtggttaa
      181 tagagtaaga gtgtaaatag agataaactt caatatgggc ttaacttgtg attaatagag
      241 taagagtgta actaaagata aacttcaata tgagcttaac ctatgattaa tagagtaaga
      301 atgtaaatag agataaactt caatatgagt ttaacttgtg gctaatagag taagagtgta
      361 aatagagata aacttcaata tgggtttaac ctgtggttaa tagagtaggg tgtaactaaa
      421 gataaacttc aatatgagtt taacttgtgg ctaatagaat aagattgtga ataaagttat
      481 agttttagat gggtattaac ctgttactaa tagaatatga ttaggtgtaa aattatagag
      541 ctgtataaga aaatattata gatatattaa atattagata ataaatattt atatagatac
      601 acaaaagaaa aggcgatatg aagctaaact taatgacttc atatcgtttt ttatttgaaa
      661 ctcctttgta tttagagtgt gatttttaat attgaggttt tatgtgatta agtcacagat
      721 aaaaagtaag tatcttgata taattcttat agattaataa tatagggagg ttattatgtc
      781 taataaaaaa aagaagtatg caaatatttt agcaaatgag tgcgttgctt gtggtagctg
      841 tataaaagca tgtccaagaa gtgctatctc agttccatgt ggcattagtg caaaaattaa
      901 tagagattta tgtgttggat gtgggatttg tgaaaagata tgtccagcat ctgtaattga
      961 gattataaca atattaaaag aggaagaagg taagtgtcat gaataataaa aaacattggt
     1021 atgactattt atggattttt tcttcaatat atttgatatt gggatttgta aatattattt
     1081 tcgcttggat tgggctaatt tgtttctttg ttccactagc tatttctatt gttaagggaa
     1141 ataaagctta ctgtaataag tattgtggaa gagggcaact gtttaatttg cttggaaata
     1201 aattgaagct gtcaagaaat agagatattc ctaaatttat tagaagtaag tggtttagat
     1261 atgggttttt gacatttttt atggtaatgt ttgctaatat gcttttttca acttatttag
     1321 tgtttgaagg aagtagaaat tttaaagaag tagtgacttt gttgtggact ataaaaatgc
     1381 cttggcaatg ggcgtatcat ggaactttag tttcaccttg ggtggtacag tttgcatttg
     1441 gtttttatag tgttatgctt acatcaactg ttcttggttt gattactatg atattgttta
     1501 aacctcgttc atggtgtgtt tattgcccta tgggtactat gactcagatg atatgtaagg
     1561 caaagagtaa gtctgtatag aaaggcctta tgtgatattt acagttttgt tcaagtagag
     1621 atgagtagta ggtttgaata tatatgacaa atatatgagt ataggggcat agatttagtt
     1681 tgtgtaaggc aaactgattt atgcttcttt tttatgtctt agattattgg ctaagtagaa
     1741 acaatgaatt tagatattaa gaattattca gttatttgaa gaaaatagaa taataattaa
     1801 cattatatga atggatattc attacatata agcagttaat agcaagattt atttaatatg
     1861 aaataggtca agtatttaaa ctaaataagg tcatgacaat taatataagt atagatataa
     1921 aaagattaga agttataact tataaaaggt attctatata agtagtatgt ggaaaatagt
     1981 caaattaact tattagaaac aaaaaatata cataaaaaat aaatgtaaat atcaaataag
     2041 atactatata aaaatagata taagtatctt ttttattatt gaaattatga aaatatattt
     2101 tattttacac aaaaaagagt gcctcatgaa ctaaaaagtt cattttgaga cacactttta
     2161 cagtgtcaaa gaacgaagtt tatccttatc caatactttt ataccaccac gagataaaga
     2221 cacaatacct tctctagcaa aatatttcaa cattctcgat acaacttctc tggcactacc
     2281 catatactta gcaatttgct catgagtcat atttatagtg ctactgccat ttttagctat
     2341 ctcatcaatt aaaaaagatg ccaaacgctt atcaaaactc ataaaaagaa tttgttgtat
     2401 agcccacata acatcagaaa aacgttcggt agctaattta tatgaaaata actctgcatg
     2461 aatattttct gtagataatt ttgcaaaaac agaggaacta atctgtataa tatcgcagtc
     2521 cgtttcagca tctacataga catcaaaagt tattgttttt agaatacagg aagctgataa
     2581 aatacataca tctccatcat caagtcggaa cagtgtaacc tctcgacctt catctgaaag
     2641 tatgtatgta cgcactgttc cagactttat aatcaaaata ccaatacagt cactatcacc
     2701 acaatgtact ggattccctt ttttgtaatg cgaggtattt gctgaagaaa ttaataattc
     2761 tttttgtaag tcagtaagtt tatcccaaaa aggcaagcta tgtgtaagta tatcaatttc
     2821 attttgtgaa atcatacaat atctcctttc ttaaattgtt ataatcccat gatacaagtg
     2881 aatagataaa ttgacaagta gtttgttaag aggattattt agtcagatag taatagtatg
     2941 atttatgtag aaaaaatatg ataatatgta ttcttgctat taatgagaaa gtaatatgtt
     3001 ttgatgatag taggtttgta taactaatgc ataccgttta tttttaaaag attaagttcc
     3061 ttatgtaacc ttatagacat aaaaccagca attatagcag ccatcaaatc ggctattggt
     3121 tgtgcatata agataccatt taacccatag aatacaggaa taatcaaaat tatagggata
     3181 aaacagacac cttgtctaca catacctaaa aatccacctt cctttgcttt tcctagtgcg
     3241 aggaataatg tagaatacac tgtatagaat ccaaatagca taaatgaaaa cccatttgcc
     3301 ctaagagctt tactaccatt ttctattaat aaaatgtcac cacttgtaaa ttgtgaaatt
     3361 atagattttg ggaagagtat caatataaga ccaagcacta cacaaaatac tgtagtccat
     3421 aatatggaag tttttattgc tatatgtaat ctatcgtagt tctttgaacc aaaattataa
     3481 ccagcaattg gttggaaacc ttttataaaa ccaaatacaa taagactacc taaagatgtt
     3541 attcgtgtta cagcacccat tccagctatc acagaatcac catactttgt agcctccata
     3601 ttagttaatg taatggcaag actagtcaat aattgaaata ttaaggtagg tatgccaatt
     3661 tttaggattt ctgaaaaaat ttcttttgaa aaacagcatt cgttaattct aaaactaaat
     3721 atacttttct tgcttaaaat atatcctaca taaacaagtg ttgaagcaat ctgtgagata
     3781 gctgttgcaa tagaagcacc ccttaccccc agaccaaaag tataaatgaa tatcgggtct
     3841 aaaatcatat taagcaaagc acctaataac atagcacaca tagttgtttt agcagctcct
     3901 tcacttgtga caatattagt catagtgaca ttgaatatat taaaaataga tgacacgaca
     3961 taaatgctag cataagatat tgcataaggc ataatacttt ttgtagctcc taacaatttt
     4021 aaaattggat tgagaaaaat cataatcaca ataataacta atgtacccac tataatacta
     4081 ctgtaaatag atgtacttac cacttttcct gctttttcat tatcaccatg ccctaaaagt
     4141 ctggcaatat atgaagcagc tccatttcca aacaataatc ctaatcccac aacaagctga
     4201 cctaatggaa atgcaacgga tatagctccc atttgacttg ttccaagtcc acccacaaag
     4261 tatgcatcaa ccaaattgta taatgcagtt atcatcatac ctatcatggt aggtaatccc
     4321 atagataaca atgcttttga gattggggca gaccctaata attcaattct tttgttactt
     4381 tctttcatac ttaacactcc ccttctattg acattaagtc taaattataa tactataaat
     4441 tatagtaagt atggaaaata gtactataat ttatagtatt tgtcaatagt aagaaaacta
     4501 aaggagatga tttttatggc tacaatagat ttaattgtat tgggaatagt aaagcaacaa
     4561 cccaagagtg cttatgatat tcaaaaggca gtggaataca ggaatatatc acgttgggtt
     4621 aaaataagta caccatcaat ttataaaaaa gtaattcaat tagaacaaaa gggatatatt
     4681 gaaagtaaaa ctgtgaagaa tggaaaaatg ccagaaaaag cagtttattc attaactgaa
     4741 ttaggtgaga cacatttttt agatttaatg tttgatacat ctagcaaacc aataaatatt
     4801 cttttagatt ttaatgctgt tatagtaaat ttaaatagcc ttacaccaga aaaacagaaa
     4861 ttatgtctca ataatattga agagaatgtt caagagttaa agaaaactat tgaggaaaat
     4921 ataagtataa agacagaagt accagagaca gcaaaagcag tgttggagca acagttggtg
     4981 ctagcacaag cattggaaac ctggataaat tctttaaaag ataatatggg aaattagaat
     5041 tagagaagct aacttaataa tcattaaaca aaaaccagca tatttaataa tgagatatta
     5101 gaaaaaataa aacaaatgat ataaactgaa aagtatattt aaaataaagc tcacttaatt
     5161 gagggagaat gttaaacttt t
//
LOCUS       DAEOTL010000157         5151 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEOTL010000157 DAEOTL010000000
VERSION     DAEOTL010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.159"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            62..1933
                     /locus_tag="KRH82_003792"
     CDS             62..1933
                     /locus_tag="KRH82_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBG8657040.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADIDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            2040..2747
                     /locus_tag="KRH82_003793"
     CDS             2040..2747
                     /locus_tag="KRH82_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBG8657041.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSENEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELATNKIQYVHAP"
     gene            2780..4615
                     /locus_tag="KRH82_003794"
     CDS             2780..4615
                     /locus_tag="KRH82_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBG8657042.1"
                     /translation="MKISKKIVSLLTITFLTIMLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWTKSESAVLVNDNSIADALSATPFAKAKDVPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(4663..5058)
                     /locus_tag="KRH82_003795"
     CDS             complement(4663..5058)
                     /locus_tag="KRH82_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBG8657043.1"
                     /translation="MILKKYKETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
BASE COUNT         2197 a          584 c          903 g         1467 t
ORIGIN      
        1 attataattg gtaaataagg aaaaaataat aaaaatttga attttttagg gggaaaatac
       61 catgaataaa aaaaatcttt ctgtaattat ggctgctgca atgataagta catcagtagc
      121 tccagttttt gctgcagaaa ctacacaggt aaaaaaagaa acaataacta agaaagaggc
      181 tacagaatta gtttcgaaag ttagaggttt aatgtctcaa aagtatacag gaggttctca
      241 agttggacaa ccaatatatg aaataaaagt tggtgagact ttatcaaaat taaaaataat
      301 aactaatata gatgaattag aaaaattagt aaatgctttg ggagaaaata aagaacttat
      361 tgtaactata acagataaag ggcatataac aaatagtgca aatgaagtag ttgcagaagc
      421 aactgaaaaa tatgaaaatt cagcagacct ttccgctgaa gctaattcta taacagaaaa
      481 agctaaaact gaaaccaatg gaatttataa agttgcagat gtaaaagctt catatgatag
      541 tgctaaagat aagttagtta taactttaag agataaaaca gaaacagtaa cttctaaaac
      601 tatatatgta ggtattggtg atgaaaaagt tgatttaaca gcaaatccag ttgattcaac
      661 tggaacaaat ttagaccctt ctgcagaagg atttagagta aataaaatcg ataaactagg
      721 tgtagcagga gctaaaaata ttgatgatgt ccaattggcc gaaataacta taaaaaatag
      781 tgacctaaat acagtttcac cacaagattt atatgatgga tatagattga ctgttaaagg
      841 taatatggta gcaaatggta catcaaagtc aattagtgat atttcagcaa aagattcaga
      901 aacaggaaaa tataaattta ctattaagta tactgatgca tctggaaaag caacagagct
      961 tactgtagaa agtactaatg aaaaagattt aaaagatgcc aaagctgcat tagaaggtaa
     1021 ttcaaaggtt aaattgatag ctggagatga tagatatgca actgcagtgg ctatagcaaa
     1081 acaaacaaaa tatactgaca atatagttat agttaattca aataaactag ttgatggatt
     1141 agcagctaca ccacttgctc aatctaaaaa agcacctata ttattagcat ccgataatga
     1201 aataccaaaa gtaactttag attatataaa agatataatt aagaaaagcc catcagctaa
     1261 aatatatata gtaggtggag aatcagcagt atcaaataca gctaaaaagc aattagaatc
     1321 agtaactaag aatgttgaaa gactagctgg agatgataga catatgactt ctgtagcagt
     1381 agcaaaagct atggggtctt ttaaagatgc atttgtagta ggtgcgaaag gggaggctga
     1441 tgctatgagt atagctgcca aagctgctga acttaaggct cctataatag taaatggctg
     1501 gaatgatctt tcagcagacg ctatcaaatt gatggatgga aaagagattg gtatagttgg
     1561 tggttctaac aatgtatcta gtcaaattga aaatcaactt gctgatattg ataaagatag
     1621 aaaagttcaa agagttgaag gagaaacaag acatgatacc aatgctaagg ttatagaaac
     1681 atattatggc aagctagata aactatatat agcaaaagat ggatatggaa ataatggtat
     1741 gctagtagat gcattagcag caggacctct agcagcaggt aaaggtccaa tacttctagc
     1801 taaaactgat ataacagact cacaaaagaa tgcacttagt aaaaaattaa atcttggtgc
     1861 agaagtaact caaataggta atggagttga attgacagta atacaaaaga tagctaaaat
     1921 actaggttgg taataactta tactgtggag aagattcctt aattaataca ggaatctttt
     1981 tctataatta tgctatttat tgtaaattat aacattttat aaagtaggag gatgtagtag
     2041 tggtagatgc aactttattt tttacaccac atcaagatga tgaaacctta agtatgggaa
     2101 gtgctataat tgaacatgtt gaaaaaagtg atacacatgt catattatgt acagatggta
     2161 gtaaatctat aataagaaaa gttttggatg atggagggtc atgttcttat catattaaag
     2221 atgttcataa atactcttta tcagaaaatg aattttcaaa agatagagat gaagaattta
     2281 aggatagctg tgaagcaatg ggtgtaaaag aaagtaatat acatatagaa gataatagag
     2341 cacatgatgg tgagttaagt aaagaaaagg caagggaaat aatacttaag tacttagaag
     2401 aatatccaga tgcaaaagta aaaactgtta ctccgtttaa agctagtgga atacatgaag
     2461 accatagggc attaggagaa gctgcactag agttatataa agaaggcaaa ataaaagatt
     2521 taagatttta tgtagaacca tatgactata aggattttaa aaaagttaat ccaaatgtag
     2581 aggtatggaa ggtattacct agtcaagaag agaaattatt aagtgcaatg aatgcatata
     2641 aaaaatggaa tcctgaaagt ggacattatg ctataggata ccattcagta aaatctcatt
     2701 ttgatgagct agctacaaat aaaatacagt atgtacatgc tccataaaat attatgaaag
     2761 aattaggagg taagaattaa tgaaaatatc aaaaaagata gtgtccttgt taactataac
     2821 atttttaact attatgttat atggaaatac atctaatgca tctacaaaag atacattaac
     2881 aggttctgga agatgggaaa cagcaataaa aataagtcaa gctggatgga caaagtctga
     2941 aagtgctgta ttagtaaatg ataattcaat agcagatgct ttatcagcta ctccatttgc
     3001 aaaggcaaaa gatgtaccaa tattattaac tcaaagtaat aaattggata gtagaacaaa
     3061 agcagaatta aaaagacttg gtgtgaaaaa tgtatattta ataggtggtt caattgcatt
     3121 aagttcagag attgaaaagc agttaaatgc agaaaatata agttttgaaa gaatatctgg
     3181 aaatagtaga tatgatactt ctttaaaatt agctgaaaag ctagataggg aaaaatctat
     3241 atctaaaata gtagtagtaa atggagaaaa gggtcttgct gatgcagtga gtgttggagc
     3301 tatagctgct caagaaaaca tgccaataat actttctgat tcagagaatg gaactgaagt
     3361 agctgataat tttatagata gtaaagatat agaaaaatcg tatgtaatag gtggtacata
     3421 ttctatttct aattctgtag aaagaagttt accaaatgca acaagaatag caggtagtag
     3481 tagaagtgag acaaatgcaa aaattataga agaattttac aaagatactg atataaaaaa
     3541 tatttatgta acaaaggatg gtacaaggag taagcatgat ttaatagatt ctttagctgt
     3601 gggtgtatta gcttctaaaa atggttctcc aatactttta gcaggaaata agctagatag
     3661 ttctcaaaaa gatgtgttaa acactaaaat tatagataaa gttattcaaa ttggcggatt
     3721 gggtaatgaa aatgttgtag aagatgtaat agatatgcaa gaagaaacta agtatactgt
     3781 tgaaactatt gatgaactta atgttgctat aaaaaaatca gatgcaaatg acatcataag
     3841 atttaagcca gaaaaagata aaaatataac taattctttt aaaatagaaa caaataaagc
     3901 tataactatt gaatttgatg gtatatataa acaatcaata actatagata tgccaaatgg
     3961 agatataaaa aactttgggg acatagataa tgatctagta ataaataata taaaaaatga
     4021 gactttagtt aacgaaggaa gtatacaagg gatagatgtt tatgatgaga atggatgtaa
     4081 aatagagaat gaggattctg gagaaatatg gcttataacg atacttaaaa attcaaaaga
     4141 tgtatatatt ttgaatcgtg gagaaataac taaaatatct aataattctt ctagtgtaac
     4201 aataaaaaat tcaggtaata ttaatactat aagtggaagt gaagaaccat caataagtgg
     4261 taaaaaacct ataactaatg atacagataa agatgaagat aaaaaggcac gtggtttata
     4321 tcctaaagta gaatcttgta tacctgcttt aaaagattat gtaagaataa ctatatcaac
     4381 aaaaccagag agttcaaagt ataaaattta ttatagagta gttgatgaaa aaccatctgc
     4441 gaaatatgtt ggagaaaaaa ttagtactaa aggttggagt atggttacaa tatcaaatca
     4501 atcttttatt gaaagagcca aagatggatc atatatagaa gcagtagaaa tagatacctc
     4561 aaataatgaa gtttcacgat ggggaaaatc tagcattaca gatgatggaa tttagacatt
     4621 aaacttattc attttgcaga ttactattta gtaatctgct atttattttt taaaaattat
     4681 catcttgcta aacaagtaat ttaaaactat aacaactata ttagtaaata tttttacaat
     4741 aacatcattt acaaaaagca aatcaatcat tacatacata attaacattt caacgacacc
     4801 agaaagtagc ctaaaactaa caaaagacaa aaattcctta aataagaact ttatttcaat
     4861 tcttttactt tcaaacacaa aaaacttatt agtaacataa gcaaataaaa cagcaagtat
     4921 ccatgccaaa gcatttgcaa ccataaaatt aaataaaata actctagtaa aaaataaata
     4981 cgaaactata tttacaagag tagtaaatgc tccaaaaaat aaatataata ttgtctcttt
     5041 atactttttt aaaatcaaat ataatcctcc taagctaatt taatataaat atacttaaag
     5101 atactaacaa acattagtat agcacatcta ttaataaatc aatatatctt a
//
LOCUS       DAEOTL010000158         5067 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEOTL010000158 DAEOTL010000000
VERSION     DAEOTL010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.160"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(4..675)
                     /locus_tag="KRH82_003796"
     CDS             complement(4..675)
                     /locus_tag="KRH82_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBG8657044.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEP
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            1071..1976
                     /gene="garR"
                     /locus_tag="KRH82_003797"
     CDS             1071..1976
                     /gene="garR"
                     /locus_tag="KRH82_003797"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBG8657045.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGFNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDVKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHNN"
     gene            2112..3494
                     /locus_tag="KRH82_003798"
     CDS             2112..3494
                     /locus_tag="KRH82_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBG8657046.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKAPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMILLLSV
                     INGIIPLPGL"
     gene            3565..5001
                     /locus_tag="KRH82_003799"
     CDS             3565..5001
                     /locus_tag="KRH82_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBG8657047.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
BASE COUNT         1862 a          576 c          937 g         1692 t
ORIGIN      
        1 atactaaaat aacttattgt tacaaaaatc ttctaaatta atgtatttag gagtttccat
       61 atgaatgaga gtagttctgt aaatatcttc aatacatcca tttgcaatat tattaaaaat
      121 atctgtgtgc tcttttaatg ttgtttcaag ccttccttca tgtgacaatg aatcgagagc
      181 taattttttt attctgtaca tataattgtt aaacattttg tcaaattcag tattttgagc
      241 atatgaaact atagttgtgt gaaataatgt atcgtattct gcaaatgagt ttaaattttt
      301 atcacctaat aaaatatctt tttgtttatc taaaagatgt tttaatttac ttatagtttc
      361 tactgctcta ggttctttgt attgacttgt aattaaaaaa gtacaaaatc cttctattgc
      421 agagcgtatt tggaatatct ctacaatttc atttgctgta atttgatgga ttctaaatcc
      481 tttgcttgga attatatcta taaatccatc ttgactaagt ctttgaagag catctcttat
      541 aggtgttcta gagataccta tttcactagc aagttttgtt tcagaatata tttcattttc
      601 tatcatttct ccagatagta tcaattcttt taagtagtca tatgcttgtt cttgtaatct
      661 tttaaatgta gccatactta ataatacccc cctaaacaat ataaaaatac aaaaacttat
      721 ataattttaa gcatacaaca tagtgaaaat aaggtcaatc ttttgcaatt taaattgcag
      781 ataagattaa aaaatataaa aaattattga agtgtgaagc atgattaaca ttaaaggcag
      841 attaattaaa actaattgaa attagttaaa atacaaaact gtaaaagtag tatattatat
      901 ttgaaaacaa tagtatgtat taaaacttat ataggatgac taaatataat aaatgacttt
      961 aaaaattact atttattgtt aaaataaata cttttatatt ttatattgac cggtatactg
     1021 gtatgtagta tactctaaaa cataaaaaac gttttcaaaa atgtgaagat atggagggtt
     1081 ataaaatgaa attgggattt attggattag gaataatggg aaagccaatg gcaaaaaatt
     1141 tattaaaaga tggatttaat cttttggtgt atgacattaa taaatctgct gtggatgaac
     1201 ttatatcatg tggagcaaaa tacgcaagtg ttttagaaat gggtcaagaa tgtgatattg
     1261 tatttacaat ccttccaaat ggaactattg tgcaggatat attgtttggg atggatggat
     1321 tggcaaaaac tttaaaagaa ggaagtatag tagtcgatat gagttcagtt actcctacag
     1381 aatcaatatt gtgtgcaaat aaattaaaag atatgggctt agaatttata gactcaccag
     1441 taagtggagg ggagccaaaa gcgattgatg gtacacttgc ttttatggct ggtggtaagg
     1501 aagaaattta taagaaagta gagccatttt ttaatataat gggaagctca tctattttaa
     1561 ttggagataa tggtagtgga agtgttacaa aacttacaaa ccaagtaata gttaatttga
     1621 cgatagcagc agtttctgag gcatttgtac ttgcagcaaa agcaggtgca gacccagaaa
     1681 aagtatataa ggcaataaga ggaggcctag ctggtagtac aatattggat gtgaagatac
     1741 caatgattat gaatcgtgat tttaaaccag gtggaaaaat atctattaat ttgaaagata
     1801 ttaagaatgt aatgcaaaca gcacacaatt tagatgtacc actacctatg acaagtcaat
     1861 tattagaaat tatgcagaca ttaaaagtac atggacattt ggaagatgac catagtggaa
     1921 tagcacagta ttttgaaaag ttggcaggtg ttgaaataaa aaaacacaat aattaatatt
     1981 taaatatatc aatataatta aatacatatt attaggatta gattatataa atacagcgag
     2041 gttaagttat catagtaaaa gaaaaataaa attgataaat aataaagtag aatgataaag
     2101 gggtaaagat tatgattaca ggatatggac ttttgatagc atttgttata tctataggaa
     2161 ttttacttgt atcgattatt aaatttaaag taaatccatt tttggcatta ctgataacat
     2221 ctataattac aggctttatg gttagaatgc ctataaatga aatatcaacc acaatatcga
     2281 ctggatttgg aaatacatta ggtagtatag gtattgtaat tggacttgga ataatatttg
     2341 gaaatattct ttcagaatca agagcaacag aatctattgc aaaggggttg ttagctaaga
     2401 ctggagaaaa aaacagtgct ttagcagtaa ctacagcagg ttttttaatt tcaattccag
     2461 tttttatgga tgcagctttt gttataatga tgcctataat taagtatgtt tcgagagtaa
     2521 ctaagaaatc tctaatggtt tttgtatgtg cattaggagt tgggactata gtaggtcatg
     2581 cacttgtaat acctacacca ggacctttag cagttgcagc aaatgtaaat gcaaatgtag
     2641 gtagttttat actttattct ataattgttg cttttccagc agctcttata ggtggatgga
     2701 tttatggaaa acgttttgaa aaatatccag cttatgctat tgatgagaat gatagagaaa
     2761 aaaatttaga gcagggaaaa gatagcataa aaattgaaga tgatgattct tctaaagcac
     2821 caggttttgg aatttctatg ttttctttat tgttcccaat acttcttata cttatatcaa
     2881 atgtatttag tatgttctta gaaaaaggtt ctacaatgag tggagtactt gcatttatag
     2941 gagataaaaa catagcaata cttcttggaa tattggtggc aataggattt ttaaagaaat
     3001 acataaataa acctatggga gatgtagtta ttgaagctgc tgattcagca gggctaatat
     3061 tattgataac aggttcaggt ggtgcgtttg gcagtgttat aaatgcaagt ggtataggta
     3121 acttcttagt tgatactatg tctggtctta gtatatcagt tgtagtgctt ggattcttat
     3181 taagtgcctt gcttagaatt tctcaaggtt ctgctactgt agccttagta acaacatcat
     3241 caattttagg acctacaatt ttggcaactg gaatgtcacc agttttagta gggcttgcta
     3301 tatgtgctgg aggagttggt ttctcccttc caaatgattc tggattctgg gtactttcaa
     3361 gatttagtgg attatcagtt aaagatactt taaactcttg gacaattgga ggaaccattg
     3421 ctggagttgt agcatttata atgattttat tgcttagtgt tataaatgga attataccac
     3481 ttccaggtct ataaataaca aactattgtt tatatcatat aaattacatt tagactatac
     3541 aaattacata aaggggcgtt ttaaatgaga gaagtaaaac caattagcat agatatactt
     3601 aatactttta aacaagtaga tgaggacaga ttaaataaac ttcttgcaga tgagcttaag
     3661 catttagata gaaaaattgt tgtattagat gatgacccaa caggtgtaca aacagttcat
     3721 gatatttctg tttatactga ttgggataag gatagtatgg aacaaggttt taatgagaaa
     3781 aatagtatgt tttttatact taccaattca aggggattta ctgttgctca aactacaaaa
     3841 gcacataaag aaatttcaaa gaatattgtg gatgtatcaa agaaagttaa taaggatttt
     3901 ataatcataa gtcgtagtga ttctactatg agaggacatt atcctcttga aactaattta
     3961 ttaaaaagtg aagtagagag attatcgggg aagttatttc agggtgaaat aataatgcca
     4021 ttttttaaag aaggtggtag gtttactata gataatgtac attatgttaa agaaggagaa
     4081 atacttgtac cagcaggaat gactgaattt gcaaaagata aatcttttgg atataaatca
     4141 tctgatatag gtgagtggtg tgaagaaaag acaaatggaa agtacaaatc tagtgatatg
     4201 atatatattt cgtcaaaaga acttagagag ctaaatattg aagctataac agaaaaactt
     4261 aaaaaagctg aaggattcaa taaaattatt gtaaatgcaa ccgattatgt agatgtaaag
     4321 gtatttacaa ttgcgtttat acgagcagta aatagtggta aggaatttat gtttagaagt
     4381 gctgctgcca taacaaaagt acttggcgga gtgagtgaca aggaactact tactaaggat
     4441 gaattagtat caaaaggtaa taccaatgga ggaattatac ttgttggttc acatgtgaat
     4501 aagactaccc aacagttaga agaacttaaa aattgtaaat atccgataga atttatagaa
     4561 tttaatcaac atttagttct tcaagaaaat ggtctaaaaa atgaggtaaa aagagttata
     4621 aaagttgtag aggaaaaaat aagcaggggt aaaactgttg ctgtttatac tagacgagag
     4681 cgttttgact tggatacgaa tgataaagat aaacagctta tgatttctgt agaaatatca
     4741 gatgcagtta ccagtataat tggtatgctt aatgtaagac caaattttat tatagctaag
     4801 ggtggaatta cttctagtga tgttggtact aaagcactaa gagtaaaaaa agctacagta
     4861 atgggacaga taaaacctgg tataccagta tggatgacag gcaaagaaag caaatttcct
     4921 aatatgccat atataatttt ccctggaaat gtgggagaga ttagcacact tagagaatca
     4981 gttgagatat tgatggggta gtatattagt gtattgaagt ttaaacgctt aaatttactg
     5041 agttaaaatt aaaataaact aaaatta
//
LOCUS       DAEOTL010000159         4862 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEOTL010000159 DAEOTL010000000
VERSION     DAEOTL010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4862
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.161"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     misc_binding    357..595
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            659..2578
                     /gene="thrS"
                     /locus_tag="KRH82_003800"
     CDS             659..2578
                     /gene="thrS"
                     /locus_tag="KRH82_003800"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBG8657048.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3346..4437
                     /locus_tag="KRH82_003801"
     CDS             3346..4437
                     /locus_tag="KRH82_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBG8657049.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSSLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
BASE COUNT         1917 a          481 c          864 g         1600 t
ORIGIN      
        1 ttatttgatt gtgttactta ttaatagtat ttactgtact acttattaac tatattaagt
       61 attgattgta tttaagtata caaaacctaa aaagagtaca aaaattagaa gttagtttta
      121 ataaaaatta gttttagtat ttatctagtc atatctatca tgcatgtgga tacgttttaa
      181 aaattttaaa tttatgaaaa tattataata tcactataaa tcaagagatt aatttaatat
      241 aaaaatataa gaatattggt ttacagctga ttgagatgaa aaataatggg taattaatat
      301 attacattaa tgttgattga tgtataacta tctgttataa tgaaaatata ttaaaaatca
      361 tagtgttgaa gaggaagagt agagtagaaa ccattctcag agaatttggg tctatggctg
      421 agagcccatg taataggtct atttgaaaac taccttggag ctgagcttat tagcagtatt
      481 tgtatttgta ctatacgtga aagtgctcgg gtgacgacct tatagtcatc aagagggttg
      541 tatatacttg tatacgccaa cttgggtgga accgcgaatt aatatcgtcc caaacatatt
      601 tggggcgatt ttttattaca aaaaatctaa aaattatttc aataaggagg aaaaaataat
      661 gattaaagtt gctttaaaag atggctcaat aaaagaattt gaaaatgcta tttctgttat
      721 ggatgtagct aaatccatta gtgaaggatt agctagaaat gtggtagcag cgtctgtgaa
      781 cggagaggtt gtaggtctgg accacattat agatactgat tgtgacttga atttatttaa
      841 gtttgaagat aaagaaggta aggaagtttt tagacataca tcagcgcata tattagctca
      901 agctataaaa agactttacc cagaagcaaa gcttgctata ggaccaagta tagaaaatgg
      961 attctactat gatatagatt tagaccatag attagttcca gaggacctag agaaaataga
     1021 agctgaaatg aaaaaaatag ctaaagaaga tttaaaaata gaaagatttg aacttcctag
     1081 aaatgaagct ttagagctta tgaaagaaca aggagaagac tataaggtag aacttatatc
     1141 tgatttacct gaaagtgaaa taatatcttt ctacaagcaa ggtgatttta ctgatttatg
     1201 tagaggacca catttaccat ctactaaaaa ggtaaaagct gttaaattac aaagtgtagc
     1261 aggtgcatat tggcgtggtg acgaaaataa taagatgctt caaagaatat atggaacttc
     1321 ttttgagaaa aacaaagact tagaagagta cttacattta ctagaagaag ctaaaaagag
     1381 agaccacaga aaattaggta aagaattagg attatttatg atacctgaag aaggtccagg
     1441 attccctatg tttttaccaa aaggtatgga acttaaaaat gaattattaa aattctggag
     1501 agaaatacac agaaaagctg gatatattga gatagaatct ccaatcatat taaatagaaa
     1561 attatgggag acttcaggac actggtatca ttacaaagaa aatatgtata cagttaaaat
     1621 agatgatgag gattatgcta taaaacctat gaactgtcct ggtggattaa tttactataa
     1681 ctctcaacta cattcatata gagatttccc aatgagagtt gcagagcttg gtagagttca
     1741 tagacatgag ttatctggtg cattacaagg attaatgaga gttagagcat ttactcaaga
     1801 cgattcacat atattcatgt taccagagca aattaaggac gaaataaaag gagtagctaa
     1861 cttaatagat ggtatctaca aaacttttgg atttgaatat aatttagaat tatctacaag
     1921 accagagaac tctatgggaa gcgacgaaga gtgggaagca gcagaaaatg gattaagaga
     1981 agctttagaa gagttaggtc taccatatac tattaatgag ggtgatggag cattctatgg
     2041 tcctaagata gacttccatc taaaagattg tttaggaaga acttggcaat gtggtactat
     2101 ccaattagat atgcaacttc caagacaatt tgataatact tatattggtc aagatggtga
     2161 aaagcataga ccagttatga ttcatagggt tgcttttggt agtatagaaa gatttatagg
     2221 tatattaata gagcattatg ctggtaaatt cccagtttgg ttatctccaa ctcaagttaa
     2281 gatacttcct atatctgata aatttatgga ttatgcaaat gaagttaaga aagagttatt
     2341 tgataagggt ataagagttg aattagatga tagagctgaa aaaattggat ttaagataag
     2401 agaagctcag cttgaaaaag tgccatacat gttaatagta ggtgaaaaag aagtagctga
     2461 taataatgtt tctgttagat caagagataa aggtgaaata ggtagtatta aattagatga
     2521 atttatagct agtatttcaa aagaaattga atcaagagaa agtattattc aagactaata
     2581 tatattattt tagtagctaa gatattgtta tataagataa gtttaatcaa tatgttgata
     2641 tgttgatgca tagtgattaa atttatgaaa agatgagtat aattagaggt acagttaatc
     2701 atatttttat gattaatgta cctctagttt tttgtatggt agatttatta ataaatatat
     2761 catagaagtg ttttgaacaa ggaaatattt atgtgcattc tttaaataaa agtttatttt
     2821 ttgagtgata attaagtgct tgttggtaag gttatggctg taaaaatcat aactttattt
     2881 tcatatttgt tccattttca taaaaattat tataccttta agaaaatttc ttaatcctct
     2941 tgaaatattt cctttttagt ctaaagttaa atttctttct tcaaaatgaa tatttaaatg
     3001 aactaaaatt taagtacatt ttctaatctt atgagtctat ttttcataga taattgccct
     3061 ataatagaag aatctatgtt ggtgctatgt ggtgacaata acagcattgt cagtgattaa
     3121 ttaatgcttt ataaatgatt aattagtgtt ttatgttatt tttggactta ccctctatac
     3181 atagattaat ttatttaact ttagatagag agagaatgtc aagtacatac acagacatta
     3241 gagtttaaga aagtgtttat ggagcaagaa cttttaaaag aggtagtgac ttagtttaat
     3301 ttcaagaaat gataaataca aaagaggaaa aagagaggtg ttgaaatgat agaaaaagta
     3361 gaagaaaaat ctaagattat taaaacatca aaagaatata agcgaactat aattgaagaa
     3421 aaagataaag aatggaccaa aaaattaaat gatatactta gtagaagtag tttttctaat
     3481 gatgaattag ataaaatcaa ggcgttaatt ccaaaagaga ttttgactaa tgaaaatgtt
     3541 ggagaagttg tgactgaaga tggatatgct aagcccgagt atgatgaggt atttaaatca
     3601 ttgttcactt taaataatga atatgattta cttgtaaatt ttataaatga tatcctaaaa
     3661 gatgctccat atgctaacag gaatatcaaa ccgttcactc aaataaagag aataattaga
     3721 gttgaaactg acccaacaat taattacatt ggagagaaaa gacctagact tgatattttg
     3781 gctgaagatg aagaaaataa tcatataaat attgagatgc aaagagcttt tgagaacgat
     3841 tatttggaaa gagctgaata ttatcttagt cgtgtacatg gtagaaagtt agaagaaggt
     3901 aaagagtata aagaaattgg aaaaactatt ggaatacata tactaaatca tgtaaaatat
     3961 aatcacatag aagattatgt aaattgcctg agattaacaa tggacgggca tccagatatt
     4021 tattctagta aaactgcatt atattttata gagcttccaa aaattcataa atctgactat
     4081 atagtaaata gaattatgct atggggaaaa cttattagta atccttctag cttagatgta
     4141 agagttatag ctaagaatga ttctattatt aaaaaagcac ttgatagatt aaaagaatta
     4201 ggtagcaatg aagaatattt attaaatctg aaaagaggtg cttatatcat gaataaaagt
     4261 agaaatttta aagaagagat tgaaagagag acagcaatta gagttgcaaa agaaaaagat
     4321 tataaaataa ttataatgtt gaaaaaaaat ggttttaaat tagatgacat attaaataaa
     4381 tttaatgatt ttgacttaag tgaagatgag ataaaagaag tatatgaaaa taattgatga
     4441 taaaaagtga acttatataa gtttgctgaa tcggagtctg gaaatattta tgtgtatttt
     4501 ttaatgaata aaaatttatt ttaaaaacaa taatttagag gtacagttaa ttatattttt
     4561 atgatactgt acttctagtt ttttctattg tagatttatt atttactaat aaatctacaa
     4621 tagaagtgct tttgttgtaa gaatcatttt atctaatgat tgttttttat aatagttaaa
     4681 tttccatttg tagtgtttaa atataaatct ataacagcat ttctataaat gttataaatc
     4741 actataatga ttcaactcaa agttactgct taaagaagca gagattttat caaggtatat
     4801 catggaaaaa aatattttat tgtaatattt ataagatttt attatggaaa taatgtaaaa
     4861 ac
//
LOCUS       DAEOTL010000160         4792 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEOTL010000160 DAEOTL010000000
VERSION     DAEOTL010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4792
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.162"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            143..1312
                     /locus_tag="KRH82_003802"
     CDS             143..1312
                     /locus_tag="KRH82_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBG8657050.1"
                     /translation="MNKLCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(1475..2017)
                     /locus_tag="KRH82_003803"
     CDS             complement(1475..2017)
                     /locus_tag="KRH82_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBG8657051.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(2165..2449)
                     /locus_tag="KRH82_003804"
     CDS             complement(2165..2449)
                     /locus_tag="KRH82_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8657052.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(2512..3276)
                     /locus_tag="KRH82_003805"
     CDS             complement(2512..3276)
                     /locus_tag="KRH82_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBG8657053.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSITQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(3558..3824)
                     /locus_tag="KRH82_003806"
     CDS             complement(3558..3824)
                     /locus_tag="KRH82_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBG8657054.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(3866..4675)
                     /locus_tag="KRH82_003807"
     CDS             complement(3866..4675)
                     /locus_tag="KRH82_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657055.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         1638 a          660 c          661 g         1833 t
ORIGIN      
        1 aattcaaaat aaataactta tgtaagaacc gtaggaacta ctgggatagc ctgtggagaa
       61 ttagtaagac atattttagt atgcaaaatt ctgtgaagca ggaaccctgt gactttagtc
      121 atgggaggtt cagggtagaa agataaataa actttgtaaa gatgaagttg tagagttttg
      181 caatagaata aaaggtaaag tggaaagtgt tgcaataagt ggagtatttg ctccagtaaa
      241 taaacaacaa gaagaagaag ttgcaaaatg ggttagagaa attttagggg atattcctat
      301 atctttatca aatgaaatag gtaatatagg tatattagaa agagaaaatg gagctatttt
      361 aaattctgca ttgtctcaag taggtaaagc tgtatcttta ggatttgaaa aagcacttaa
      421 agacttaggt atagatgctc aaatatattt cagtcaaaat gatggaacat taatgaattt
      481 agagtataca atgaaatacc caatttttac aattggatgt ggaataacaa attctataag
      541 aggagcttcc ttcttatcaa aagtaaaaaa tgcaatagta ttagatgttg gtggaactac
      601 aagcgacttg ggtgtactat ataatggatt ccctagagaa tcatctattc cagttacaat
      661 tggaggagta catacaaact ttagaatgcc agatgtttta actattggtc ttgctggtgg
      721 tacatgtgta aaaggcgaaa aagataatat aaagataggt cctgaaagtg tgggatatag
      781 aataactgaa gatgcaataa tatttggtgg agacactcta actttatcag atgttgttac
      841 aaaattagat atggcgtttg aagatagaaa aagcaatgtt gaaaacttag ataaagagta
      901 ttgtaatgag gtatataaga aggttatttt aaaattagaa gatgctgtag accaaatgaa
      961 gactagtcaa gatgatgttg aattggtttt aactggtgga ggaagtataa ttgttcctga
     1021 aaaactaaaa ggcataagca atgttataag acctcctcat tatactgctg caaatgctat
     1081 tggtgcagct ttaggacaaa taagtggaga tgtagaaaaa gtatacagtt tagataaaat
     1141 gtcgagagaa gatgccatag aagatgcaaa aaaagaggct gtaaataaag ctctaaaagc
     1201 tggtgctaaa gaagatacta tagaagtatt aaatatagaa gatgttccac ttgcatacct
     1261 tcctggtaat gcacttctta taaaagtaaa agttgttggt gatttaattt aaagaataaa
     1321 tataagtatt tccagaatta tataaatatt tctggactca tttttaaact tattttatca
     1381 ataaaaacag cataactttt gactatattc ttataagttt ccgaacagcc gatatatacc
     1441 tattttttga ggtttatcgg ctgtttgtta tcttttatcg cattccaact atttttctta
     1501 ccgtatttgc tgtacgaatt gtaatcttat cacttacatt tgaactggca gtctttgacc
     1561 accaatttgt ctttttataa tctttacgac taaaagacca aaagatagca tttttataat
     1621 gatatacttt ttcatactct tctttaggat ttccaacctc atcataaaac tcgtcataag
     1681 ataagtcagg aaacataaaa ataagattat catatatttc tttgttgtta tctccccacc
     1741 aattaggagc attatttagt atatctttta actcttcttg tgaaataata aaaactggta
     1801 tttccaattc aaactgtttt tttatcatta atcttattgt atttgagata accttgctgt
     1861 catctacatc acttaaaaag acaacattac cactattaag gtatgtagaa acttctgaat
     1921 aaccaagttc tacaaagctt gcttttaatt cagacataat tatcttgttc ttaccactta
     1981 tattgatacc tcttaataat gcgatataac ttttcatata ataatttcac ctctaaatat
     2041 tcacattttt ctatgtagta caaactggaa tttgcatctt ttataattct ttcaaaactt
     2101 cttcatatgt aattttttta atataaaaaa atcggtgctt aatttgtacc gatttttgtt
     2161 tttcttagta aagaactcgt ttttttgctt ctgctatagc tctagcagca ctttttgctt
     2221 gcattctttt ttcttcttct tttttaaatt catttattgt ttcatttaga ttcttatcat
     2281 gttcattttt ttctttatct tcgttttctc tgtatactaa tatataatct attattgatt
     2341 cgtttattat ctgagatata cttttatttt cattaattcc tattctctta acttccttaa
     2401 gtagagtctc atcaatatga accgttgttt gctttgtatt ttttgccacc ttaatcacct
     2461 cttaaaaaaa attctaacat taaaattttt tttagtcaat aaattttaat attaaaattc
     2521 tttaaatgtt ttatttgatt ttctaaaatt ttctattgta tttatcatct tattttttat
     2581 attttcacct agtacagaag actttagtct aggattttcg atatggtcat aaattggttc
     2641 taaaaattcg acttcgacag gaacagagtt aattttacca ataggttggt atccttcata
     2701 agtatctttt gaatttttta ttactagtgg aacaataggg cattttgctt tatatgctat
     2761 ctttaaagct ccacttctaa actccgaaac caatgaattt ggttctttaa tccatgttaa
     2821 atctccttct ggaaacactg ccatactttg acctgtaagt atattttgag aggcttgggt
     2881 tatactcttt ataccctcac gattgttttt tctgtttaca tatacacatc ttagtaattt
     2941 tgcccattct ttaaatatag gtatatttct ccaaactggt tcatctgcaa ttacacatcc
     3001 aattggtctt tctacacttg ctgttagtat gaagctgtca agcatactag aatgatttac
     3061 aacaaataga agtggttctt ttggcagtgt ttccttacca attatattaa gctctatgtt
     3121 cactatatct aaagattttt tagcttgttt ttgcataaat tcaaattttt cctttaagct
     3181 aaatttatca ggattctttt taattttaat aagcctaggt atagaagatg taaaacctat
     3241 aagttgatat gtagcaaatt ttaagtaatt attcataaaa ttatctcctt aaaataaaat
     3301 tatttattac tgtaaagatt ttaacataaa ataaaattta agtctatttt aattcaattt
     3361 tgtaacatat attttaaata tacagagatt gagattttat atttccaatt ttagtaatca
     3421 gattttatca ataaattact attctattaa tttaattaaa taacctttaa atttaattat
     3481 aaaaactgtt gcagaaattt ctacaacagt ttaaaaaatt taccttacaa aaacttattt
     3541 tataacaaga gagtatatta taaggctagt acagcccatt ttttgcactg agaaattctt
     3601 ttgccatcat caccttgttc tttgtcatat gcaaattgat taagcatttc acatggaaat
     3661 gtatcacata gaccacaatg tgtaaggttt ttatcttcac aacaagattt tacaggacat
     3721 tgttcacccc aaaatggttt ctcaatctct gtacaacctt tacaattgac tttttccttg
     3781 tatccacatt cataacataa aattccacat cttgattcta tcattttaag tcactcctta
     3841 aatataaatt ttatatgatt gtatatcaaa atttatactt ttcattgtaa aaatcggaca
     3901 aattttttat ataggttgtt ggattaacac cacaaataga tttaaaatca tttataaaat
     3961 gagattggtc gtaataacca atatcttgtg ctaaagttgc aaatggtatt ttattatttt
     4021 gtatttcttg taatacaagg tttatacgaa gtaatctaag gtatgattta acactcatac
     4081 caagagaatt attaaaaatt ctatttaaat gtcgttcact ataacaacta atttgtgaaa
     4141 tgtttttaac agacataata gagttttgtt ttctagcatt ttcaagaatt ggtatagtca
     4201 tatctactat atttgatttc aataagtatg ataagaataa catatctaat tgttctacta
     4261 attcctttat agtacttgtt ctttcaaaaa tggaattaac ctctaagcta aataatgtgt
     4321 taaaatcttc aagtgaaatt tttaaatctg tagattctct ttgagaaaga cctgtcaaat
     4381 aatatactcc acctgggcga aactcaacga atactctaaa aagtacattt tctatatcat
     4441 tttttacaat agtagttttt gttgtggctc cccagaatgc gctttctata ccttttttgt
     4501 caaatttaaa tatcatacat ccactagcat caggtattaa tgtaagattt tctttaatac
     4561 ttgtatctgg aatagatatt gtatagtgtg ctatatactg tcttaacaat ttatgtggca
     4621 aaatatatgt atactgtttg caggtattta aaatgttatt gattatttta ttcataagta
     4681 tatcctcctg atatataaaa aataagtata ctaatttatt ttttatataa taaaccagtt
     4741 ttgttttaat tgaaatattc taataagata ttttgttaaa tttagataca at
//
LOCUS       DAEOTL010000161         4750 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEOTL010000161 DAEOTL010000000
VERSION     DAEOTL010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.163"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(269..2404)
                     /gene="rnr"
                     /locus_tag="KRH82_003808"
     CDS             complement(269..2404)
                     /gene="rnr"
                     /locus_tag="KRH82_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBG8657056.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQIGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            3000..3614
                     /locus_tag="KRH82_003809"
     CDS             3000..3614
                     /locus_tag="KRH82_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBG8657057.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            3632..3994
                     /locus_tag="KRH82_003810"
     CDS             3632..3994
                     /locus_tag="KRH82_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657058.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            4100..4597
                     /locus_tag="KRH82_003811"
     CDS             4100..4597
                     /locus_tag="KRH82_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBG8657059.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
BASE COUNT         1551 a          719 c          597 g         1883 t
ORIGIN      
        1 ttatttttca gttggctttt tctattaaat gtttcttaat tacttatctt tcagttagct
       61 ctttctatta aacatttctc aattacttat ttttcaatta gctactttca ttaaatattt
      121 cttaattatt tatctttcag ttaactattt ccattagata tttctcaatt acctattttt
      181 atcatttatt ttatagagta ttgtgcacta tatatttata catatcataa atactacaac
      241 ttgttatctc ttattttagc tgttttatct actcctctat tttttcaact atctcaaagt
      301 caatttcttt aaaatctaca ttaacacttt caacctttat cttaacaagg tctcctatct
      361 tatatgactt cttagttctt tctcctaaaa cactataaga actctcatca taaatatagt
      421 aatcatcatt catatttgca agtcttatca acccttctat agtattatct aactcaacaa
      481 atattccaaa tgaagttacg ctagatacaa caccctcaaa ttcttgacca actttatcct
      541 tcatataaag agccttatag aaatcatgta catctctttc agctaactct gcctttcttt
      601 ctttctcgga tgattgaaca gatgcataat ccactatagt agtaagctgt tcttgtcttt
      661 ttccacttat tttattattt aaagattctt ttattattct atgaatttga aggtcaggat
      721 atcttcttat tggtgaagta aagtgacagt agaatttagc tgctaatcca aaatgtccac
      781 tacattctgg tgagtactta gcttgtttta aagaacgaag cattatagta ctgatagctc
      841 cttcttcttt tttgcccttt attttctcta ttataccttg taatgctttt ggatgtactt
      901 cctctttatc accttttatt atatatccaa atgtagatat aaacttactc aattcttcca
      961 ttttttccaa agatggtgtc tcatgtattc tatacacaaa cggtattccc atccagtaaa
     1021 aatgttcggc aattgtctca ttacttataa gcataaattc ttctattatc ttattagata
     1081 ttcttctttc atatggcttt atatctacaa cttcgccttt tccatttaga attatctttg
     1141 cctctgggaa attgaagtct atagctcctc ttttttccct tcttgacata agaatcctag
     1201 ctaaaatttc agcattttta aaatcttcaa caacatgttc aaaagtcttt ttaagttttt
     1261 catcatcctt ttctaatata tcagatactt ctgtataagt cattctagct tttgaattta
     1321 ttacagattc acatatttca tgtttaacca catttccttt atggtctatt tccataaata
     1381 tagaaagagt taacttatct tcaaatggat ttaagctaca tactccattt gaaagagttt
     1441 ttggcaacat tggaattact ttatctacta aataaactga tgtagctctt tttaaggctt
     1501 ccttgtcaag tttatttttc tctcttacat aatgtgtaac atcagctatg tgaactccta
     1561 gtttgaagtt tccattaggt aatacttcta ttgatatggc atcatctaag tcttttgcgt
     1621 catctccatc tatagtaaat atgtttaaat ctcttaaatc tcttcttctt tttatctctt
     1681 cttgaggaat ctcaacagct acagcttctg cttcttgcaa tactttcttt ggaaattctt
     1741 ctggaagacc atgttctctt attatagaat ctatttctac gcctctttca cctttttgac
     1801 ctagtatctc tataattttg ccttctggtt ttctatcctc ttgtggccat actgtaattt
     1861 cacatactac cttatcatta tctactgctc cactaaaatg ttttttaggt atatatatat
     1921 ctttagtaaa tttcttgttg tctggtgtta caaatccaaa agttttactt gattggaagg
     1981 tacctactat tctagttatt tctctcttta ttacttttac tattcttcct tctgctctct
     2041 tttcttcagt tgcaggtact actatttctg ccataactct atcattatgc atagcaccat
     2101 ttatattgtc acttgagata aataaatcct gtgtatattc aacatcagat tctacaaatc
     2161 caaaaccctt tttgtgtgat acaaattttc caacaaagta tccaatttga ttgggagata
     2221 ctatttttcc ttttttagta aagcagatat aaccatcttc ttctaattca tttaaaaaat
     2281 tataaaacat tggcatttct gatgaatgta tatcaaatat ttctgctaat tcttcttttt
     2341 ttagaggatt atatgcactt tcatttatta atcctagcaa actttcttta agtcctggta
     2401 tcatttttcc ctcctgtttt acttttcatt atattattat ttatattgtc ttttatattt
     2461 cttcagacaa aacatttttt acttatcaca taattttcta tatttcctta ttattattac
     2521 aagttaaaat tacttattta tatttttgat ttaatgtaag ctttgtcata ctaacttcaa
     2581 acaaattatg atgttttata aattatttgt aaatatcatt ataattactt aagttattct
     2641 ttatcataat tgcttaaatt actctttatc acctaattat acaccatcaa ataggattgg
     2701 taaaatattc atctcatata agtattacta tataataatt tattctatta gtatactcaa
     2761 atcatgtaaa atttatataa ctcaattaat tttttaaata caactttata atataaaact
     2821 tataataaaa gtaaatttat atgttaaatg aggttgattt tttattattt tttatttatg
     2881 ctagtactaa agacttgcaa acgttttttg acaagtcttt attttgtcta aattaaacaa
     2941 acttttttac aaataaatac ataaaattta aactaatcta tttattggag gagataaaat
     3001 tggaagaagt aattgcaaaa attattacta tagaaaatgg attcaaagaa attgaaaaca
     3061 ttgctaaaaa aattgtaaaa aataatgact caaaaaagtg ttattatcta tcaatctact
     3121 tatataggtc agaatattat caagtaagag aattggctgt gtttatactt ggttttatat
     3181 cagtaactat ttctgaagct ttgttatttt taaaagataa tgtgagtaaa gatgaaaact
     3241 ggagagtaca agaaatacta gctaaatcat ttgattatta ttgcagtgaa gtaggatatg
     3301 aaaaggctct tcctgttata aaagaatggc ttaattctga tagtccaaac ataaaaaggg
     3361 ctgtgacaga aggtcttcga atttggacta gtagagacta ttttaaatct aatcctgacg
     3421 ttgctatatc actactttct agtttaaaag aagatgatag cgaatacttg agaaagtctg
     3481 taggtaatgc tcttagagat ataagtaaaa aatatccaga tttagtaaaa aaagaattag
     3541 attcatggga tatatcaaat aaaaaagttg agtttgtata taagcttgct tcaaaatgta
     3601 tcttggcaaa gtaaaatgga ggtgaactta tttgaaactt cgtgatgagt atacttgccc
     3661 attagaacta acacatgata tgataaaagg caaatggaaa tctattatat tatggagatt
     3721 acgtatagga ccaacttcct tatcaaaact tgaaaaggaa atcaatggta ttaatcaaaa
     3781 gatgttactt gaacaactta aagaattaat tgaatttggt cttgtagata aaaagacata
     3841 tgaaggttac ccacttaaag ttgaatactc acttacacct attcgaggga aacaaatatt
     3901 ggatgctttg gctataatgc aagatatagg aattagcttt atgttggata atggtatgga
     3961 agatattctt aaggaaaaag gtgttttaaa gtaaatagat acccacaaaa aagtaagtaa
     4021 tttaccatta ttttcaactg gtatataatt aaattataga tatattctat taatttatta
     4081 taataggagg taaattatta tgaaagtaac tagtacaggt atagtaaatg gtgttataga
     4141 agataaatac ggtaaaagag gaactcagtt caatgaaggt ggtatgccta catattcact
     4201 acctctaaag tttgaagatg ctccaaagaa tacagtatcc tttgctgtat ttttagaaga
     4261 taaagactct gttcctgtat gtgggtttgc atggatacat tggttagctg taaatataac
     4321 aaaagatgag ttaaatgaaa atgaaagtgt aacagctact gattttgtac aagggactac
     4381 tagttggcat ggtaaactag gaggtcttga cagattagag gccagtgtat atggtggaat
     4441 ggctcctcca gacagacctc atgtctatga aatacatgta tttgcacttg atactatcct
     4501 tgaccttgaa aaaggattct atatgaatga atttttcaaa gctattgaag ggcatgtttt
     4561 agatacattt acactaaaag gaagttattc taattaatta ggttgactat agctaatcat
     4621 taattaaatg ctacatttaa ttgatgatta gcttaattgt tattagaata ttttctgcac
     4681 tttatcttaa tatatatttt agttgactgg tattttaatt tctattagat tattatcaat
     4741 ttatataaat
//
LOCUS       DAEOTL010000162         4568 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEOTL010000162 DAEOTL010000000
VERSION     DAEOTL010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.164"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            69..605
                     /locus_tag="KRH82_003812"
     CDS             69..605
                     /locus_tag="KRH82_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBG8657060.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            637..1026
                     /locus_tag="KRH82_003813"
     CDS             637..1026
                     /locus_tag="KRH82_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBG8657061.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            1063..1449
                     /locus_tag="KRH82_003814"
     CDS             1063..1449
                     /locus_tag="KRH82_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBG8657062.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            1576..3018
                     /locus_tag="KRH82_003815"
     CDS             1576..3018
                     /locus_tag="KRH82_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBG8657063.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            3315..4130
                     /locus_tag="KRH82_003816"
     CDS             3315..4130
                     /locus_tag="KRH82_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8657064.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         1791 a          466 c          841 g         1470 t
ORIGIN      
        1 gcaaatgaga tactatataa atatagaaat agtaatcatt actattatta aaaagggagg
       61 aattaattat gaacttaaaa ggaactaaaa cagaaaagaa tttaatggca ggatttgcag
      121 gagagtcaga agcaagaaat aaatatacat actacgcttc aaaagcaaga aaagaaggtt
      181 ataatcaaat agctgctata tttgaagaaa ctgctaacaa tgaaaaggaa catgctaaat
      241 tatggtttaa acttttacat gatggtatgc cttcaacaga ggaaaattta aaggatgcag
      301 cagcaggtga aaactatgaa tggactgata tgtatgcaaa atttgctaaa gaagctagag
      361 aagaaggatt tgacaagata gcttatttat ttgaagctgt tggaaaaata gagaaagagc
      421 atgaagaaag atacttaaag cttttagaaa acttaaatga aggaaaaata tttaaaagag
      481 atgaagaagt tgtttggcaa tgtcaaaact gtggtcatgt gtatgtaggt actgaagcac
      541 cagaaaaatg cccagtatgt gaccatccaa aagcatattt caatataaaa gctgaaaatt
      601 attaaaaatt atcattatta aaaaggaatg ttaactatga aattttctaa acaacgagaa
      661 ctgattttaa atgaaatatt aaataatccg gttcatccta ctgcggatta cctatatgaa
      721 aacttaaaaa aagataatcc aaatttaagc ttaggaactg tgtatagaaa tttagctcag
      781 ctaacggaac atggctttat aagaaaggtt agtattccag ggtatccaga tagatttgat
      841 ggtcgaatag ataatcacta tcatatcata tgtgaagtat gtggagaggt atacgattta
      901 gaatccgaag ttcttaataa tttacaagaa ttaatatctg aggagacaga cataaaaata
      961 acatcttata acataagttt taaagggatt tgtaataatt gtaaaaggtg tagccaagta
     1021 ggttagtttt caaattctaa aaataattaa tgaggtgagt ttatgtgtag tgaacaaaaa
     1081 ttttttatat gtgagacttg tggaaacctt gtaggaatga tacaaagtgg tggtgtacct
     1141 attttctgtt gtggaaaacc tatgaaggaa cttgttccta atacaacaga tgcagcagtt
     1201 gaaaaacatg tacctgtaat tgaagtggat ggaaataatg ttactgttaa agtaagtagc
     1261 acaactcatc caatgactaa agaacatcat atagcatggg tgtatcttat gactgaacaa
     1321 ggtggtcaac gcaaatgtct agcagtagat ggagaacctg tagttaaatt tgctttgaat
     1381 gatgatgata aagtgatttc tgcctatgct tactgtaatt tacatggatt atggaaggct
     1441 gaactgtaat atttaaataa attgagtcaa aaaggaggct ataaatgtat tttcatacaa
     1501 atagcctcct ataaatttat ataaattcaa gttttaattt tgtttaatgt caatataata
     1561 taaggagaaa ataatatgtc aatttataaa tgtagtgttt gtggatatat ttatgatgaa
     1621 tctaagaatg ataaaacatg ggatgaatta agtgaagatt gggaatgccc tgtatgtaca
     1681 aaaggtcgta gttattttgg aaagataagt actgtttact atgaagaaga tgaaaagata
     1741 gcagaagaca tagttgaaga tgaatctaaa ttaaatactg aaaaagaggg agatttaaat
     1801 tacttaagta catatttaag aagagatgat gaagttgaga aacatatgga tataattcac
     1861 gaaatggctg ttacaggaaa atctataata gaacctatga gaactaaact accagtaatt
     1921 tcttgggatg atattttaat tatgggtgct caattaaatc cattaccttt aaatgagcat
     1981 gatgaagtaa atacaacaac aataatagga aaaaaagcaa agaaacctat gattatagaa
     2041 aatccagttt atatttccca catgtcattt ggagctttgt ctaaagaact aaaaatagct
     2101 ttagcaaagg gtgcagccca aaataagaca gctatgtgta gtggtgaagg aggtatatta
     2161 ccagaagaga aggaagcttc atacaagtat atttttgagt atgtaccaaa taaatatagt
     2221 gtaactgaag aaaatcttaa aaattctgat gctatagaga taaaaattgg tcaaggaaca
     2281 aaacctggta tgggaggtca tcttcctggc gaaaaagtaa ctgaagaaat agcaaaagta
     2341 agaaataagc ctgtaggtca agatgtaata agtccatctt gttttgagga aatacaatcc
     2401 aaagaagatt taaagaaact tgtagatgaa cttagagaag tttcagaagg gcgtccaata
     2461 ggtgttaaaa tttcagcagg tcatattgaa aaagatatgg aatttatagc ttatgctaaa
     2521 cctgattttg taactattga tggtcgtggt ggagctactg gagcaagtcc aaagttgctt
     2581 aaagatgcaa cttcaattcc aacaatattt gctctttatc gtgctagaaa atacatagat
     2641 acacatggat tagatataga tttggttata acaggtgggc ttcgtatatc tactgatttt
     2701 gctaaggcaa ttgctatggg tgctgatgca gttgctattg caagttctgc tcttatggca
     2761 gcggcgtgtc aacaatatcg tatatgtggt tctggtaagt gtcctgtagg agtagctact
     2821 caggatgagg aattgagaaa aagattacat atagaaaaca gtgctaatag agtggcaaac
     2881 tttttaaatg taagtttaga agaacttaag acttttgcta gaatttctgg tcataaagat
     2941 atacatgatt taagtgttga tgatttatat actgttaact ctgaaatatc aaattataca
     3001 aacatacagc atgtatagat tgaagtttga aactattaga ttttagatag ctataaaagt
     3061 aaatgataaa tatattttat aaaagagagt gtcttaaaat gaacttttta gttcataagt
     3121 cactcttttt ttgatgaagc caaatatatt tatcatttta gcaatgaaaa agaatcttat
     3181 ctctttattt tgagatagac tccttctatt tatgaaaatt aaagatatta aattgtaaaa
     3241 tattctgtga tgtcgtacta ttaaactaaa gattctgtac tttaaagtaa ataaaaattt
     3301 aaggagtgat tattatggaa agattgaaga tacaagtttt agttgacaat aatacttata
     3361 ttgatagata ctttgttgga gaaccagcag taagctatta tattgagatt gatggaaata
     3421 ggattttgtt tgactcaggg tattcagatg tattcatatc aaacgctgaa aaattaaata
     3481 tagatttagg aaatttaact catgttgttt tttctcatgg gcataatgac catacaagag
     3541 gtatccagtt tctagaaaat aggtatgatt tatctacagt tgaacttatt tcacatccta
     3601 actgttttat acctagaaaa catggagaga aaagcatagg agctccattt tctgctgagg
     3661 aaattaaaaa tatttttatg tataatccta aggataagcc atttaatcta agtaagaatt
     3721 gtgtgttttt aggtgaaata ccttctataa atgattttga aaaaagagct aaaattggta
     3781 aatgtaaaat aggagatttg tgggaagatg attatgtttt agatgattct gctatagttt
     3841 gtaaaactga taaaggtatt tttattgtta caggatgttc tcatagtgga atttgtaata
     3901 tagtagagta tgctaaaaag gtatgtggag atgatagagt tattggtata ctaggtggtt
     3961 ttcatctttt tgaattgaat aataggttag atagtacaat acaatatttg gataaagaag
     4021 aaatgagaat gttgtaccct tgtcactgtg tttcttttaa ggtaaaagcg aagatgaatg
     4081 aaatattgaa tataaatgaa gttggagtag ggctgaccat aagtatatag tatttgaaag
     4141 tatataagat ttaagttgaa ggttaaaaag atattttcta tagaaaatat cttttttgtt
     4201 acgtttattt taagagaaat caatatactt ttatatgaaa tattgtaaaa aaatttattt
     4261 ttaatgagaa tatattttca ttaataaaca attttattat gtattaataa tgttagaata
     4321 aatataaata aatcaaagtt acttacatta cagtatattt tttcacaaaa tatattgatt
     4381 tattctttta aagtttgata attccaatga atgtaataaa agaaggaatt ttatactata
     4441 cgattattat tatataataa taaagaaaaa attatataat aataaagaaa aaatgtataa
     4501 tatttaacat taaaaaagat atttcataaa attaaaaaac aaagtgaatt tgaatactat
     4561 ttaaaaaa
//
LOCUS       DAEOTL010000163         4522 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEOTL010000163 DAEOTL010000000
VERSION     DAEOTL010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4522
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.165"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            30..2441
                     /locus_tag="KRH82_003817"
     CDS             30..2441
                     /locus_tag="KRH82_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBG8657065.1"
                     /translation="MRKYKLKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATEPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDAYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            2738..4315
                     /locus_tag="KRH82_003818"
     CDS             2738..4315
                     /locus_tag="KRH82_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBG8657066.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTTSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         1818 a          539 c          846 g         1319 t
ORIGIN      
        1 aaaaattaaa tacatataag ggggtaaaca tgagaaagta caaattaaaa aaattgtcaa
       61 agctactagc attgttgaca gtttgctttt taatagtgtc aacaatacct gtctcagcag
      121 aaaaccataa aactctagat ggagtagaaa ctgcagagta ttctgaaagc tatcttcaat
      181 acctagaaga tgtcaaaaat ggagacacag caaaatataa tggagtaata ccttttccac
      241 atgaaatgga aggtacaaca cttcgaaata agggtagaag tagtcttcca tcagcatata
      301 aatcaagtgt agcatacaac ccaatggatc ttggtcttac tacaccagca aaaaatcaag
      361 gaagtcttaa tacatgctgg tctttttcag gtatgtcaac tttagaagca tatcttaaat
      421 taaaaggata tggaacgtat gacttatcag aagaacattt aagatggtgg gcaactggtg
      481 gaaaatatgg atggaactta gatgatatgt cagggagttc aaatgtaaca gctataggat
      541 atctgacagc atgggcaggt cctaagttag aaaaggacat accatataat cttaaatctg
      601 aggcacaagg tgcaactgaa ccttcaaata tggatactgc acctactcaa tttaatgtaa
      661 cagatgttgt tcgtcttaat aaagataagg aaactgtaaa gaatgctata atgcaatatg
      721 gttcagtgac atcaggttat gcacattatt caacatattt taataaagat gaaacagcat
      781 ataactgtac aaataagaga gctccattaa atcacgctgt agcgatagta ggatgggatg
      841 ataattattc aaaagataat tttgcatctg atgtaaaacc agaatcaaat ggagcatggt
      901 tagtaaaaag cagttgggga gagtttaact ctatgaaagg attcttctgg atttcttatg
      961 aagataaaac tctactaaca gatacagata actatgcaat gaaatcagta tcaaaaccag
     1021 atagtgataa aaaaatgtac caacttgaat atgctggtct tagcaagata atgtcaaata
     1081 aagtaacagc agcaaatgta tttgatttta gcagagactc tgaaaaactt gattctgtta
     1141 tgtttgaaac agactctgta ggagcaaaat atgaagtata ttatgcacca gtggtaaatg
     1201 gagttcctca aaacaattca atgacaaaac ttgcaagtgg aacagtatca tattctggat
     1261 acataaatgt acctactaat tcttacagct taccaaaagg taaaggagca atagtagtag
     1321 ttatagacaa cacagcaaat cctaatagag aaaaatcaac tttagcatat gaaactaata
     1381 tagatgcata ttatttatat gaggctaaag caaacttagg tgaaagctac atacttcaaa
     1441 acaataagtt tgaggatata aatacatata gtgaattttc tccttgtaac tttgttataa
     1501 aagctataac aaaaacatct tctggacaag ctacttcagg agaatcttta actggagcag
     1561 atagatatga aacagcagtt aaagttagtc aaaaaggatg gacttcttca caaaatgcag
     1621 tattagtaaa tggagacgca atagtggatg ctttaacagc tacaccattt acagcagcaa
     1681 tcgactctcc aattcttttg acaggaaaag ataacttaga ttcaaaaact aaggcagagt
     1741 tacaaagatt aggaactaaa aaagtttatc taataggtgg agaaaattct ttaagcaaga
     1801 atgtacaaac tcaacttagt aatatgggta tatcagtaga aagaatttca ggtagtgata
     1861 gatacaagac tagtatatct ctagctcaaa agttaaatag tataaaatct gtttcacaag
     1921 ttgcagtggc aaatggtgta aatggacttg cagatgcaat aagtgttggt gcagcagctg
     1981 ctgataacaa tatgccaata atacttacta atgaaaaaag tgagttgcaa ggtgctgatg
     2041 agtttttaaa ttcatcaaaa ataactaagt cttatataat tggtggaaca gctactttat
     2101 catcaaattt agaaagtaag ctttcaaatc caacaagact tgcaggaagt aatagaaatg
     2161 aaactaatgc taagataata gataaattct atcctagctc agatttgaaa tatgcttttg
     2221 ttgttaaaga tggttcaaag agtcaaggag acttgataga tggactagca gtaggagcat
     2281 taggtgctaa aactgattca ccagtagttc tagttggaaa taagttagat gaaagtcaaa
     2341 aaaatgtact taagtctaag aaaatagaaa ctcctattag agttggtgga aatggaaatg
     2401 aaaatgcttt taatgaacta aatactcttt taggaaaata gtgaatggaa agatagtaag
     2461 gatatacatt ttattattaa aaaatgttca atagaagttt ataaatataa aataacaaaa
     2521 aggggtgtct caaaatgaac tttttagttc atgaggcact cttttttgtt gttttatatt
     2581 tttatcattt aaataatgaa aaataggctt gtctatattt ttagatagtt ttcttattat
     2641 tgatgaaaaa tgtaataatt ttaaactgta aaatagtgta aagttatttt ataatataaa
     2701 tatagtaaga ttttaaacaa aataaggggg aataataatg aaagcaccaa aaactatttt
     2761 aacaatactg acaatagcgc ttactttaag tagcatttct ataataccat catatgcact
     2821 tacagaggaa aaattaatag gtaatggtag atatgaaact gctgtaaaga taagtcaaaa
     2881 ggcatacagt tctagttcta atgtagtgtt agttaatgac aattcattag ctgatgcact
     2941 ttcagccaca ccatttgcaa aggctaaagg agcaccaata cttttgacag aaagtgataa
     3001 gctagatgat aggactgaaa aagagataaa acgtctagga gctaaagata tttatttgat
     3061 aggaggtact gctgtactta ataaagatat agagaacaag ttaaaaggta atggacttaa
     3121 tgtagaaaga attaatggta aggatagata tgaaacttca ctgattttgg ctaataagct
     3181 taaggatata aaagatatta aggaagttgc tgtagtaaat ggtgaaaaag gattaagtga
     3241 tgctgttagc gttggagcac cagcagctca aaataagatg cctataattt tgtctagtcc
     3301 taaggacgga gtagaagcat ttgataaatt tataagggat gagaaagtta taaaagcata
     3361 tgtaattgga ggtacgactt cagtttcaag agctgtagaa aagagtcttc ctaatgcaga
     3421 aagagtgagt gggaaagata gaaatgagac taatgctaag gtcatagaaa agttttacac
     3481 tgatacaaat ttaagtaatt tatatgtaac taaggatggt agtaaaaatg agaatcaact
     3541 aatagactcg ttagctgttg gagtattggc tgcaaaaaat gagtctcctg ttgttttggt
     3601 tggtaataaa ttaaacacaa aacaaaggga catacttagt actaaaaaat taaatactat
     3661 aacacaggta ggtggaaatg gaaatgaaga agcttttgat gaaattaaaa gtctacaaga
     3721 aaaaactgtg tttgaagcaa aaactgttga ggaattaact gatatgataa atatagcaag
     3781 tcctaatgat attataaact ttaaaccaaa agagaatact gtaaatgaag cttttagaat
     3841 ggtaacaaat aaaccaataa ctgtgaatat aaagggtgat tgttcaaaga ctcttacagt
     3901 agatatgcct aatggtgaag tgaataacta tgctactttg gtaaatgtta tagttagaaa
     3961 tattggagaa ggtggattta ataaccatga tacaatcact atattgtcag ttcgtgacaa
     4021 aaatggtaga gttatagaaa atactagaaa ttcagatata gatacgttga tgatattagc
     4081 ttctgctaat gatacaaaat tgattaatga tggatatata ggaaaactta tagataattc
     4141 atctaatagt gatataacta ataatggtac tatagataaa aaagttaatc aggttgaaga
     4201 tttagaggct aaagtagatt caattgaaaa agctatagat tctataagtc aaaaagtcaa
     4261 taaaatacaa gatatactag ataagcttgg atttctaaag aaatttctta gctaagaata
     4321 tatatattta agtgaagtgt gtgttgtaat tgttctaaat ttatgtagtt aaacaggttt
     4381 atatacaaat agatttatag ataaatatgt agtttagtat atatttgaat aagctttggg
     4441 gaggtaacat ggggattgga attgaatgta acaaaaaaat aaataaaagt attgacaaaa
     4501 ctagaataaa gaaaaataat ct
//
LOCUS       DAEOTL010000164         4506 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEOTL010000164 DAEOTL010000000
VERSION     DAEOTL010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4506
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.166"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(892..1302)
                     /locus_tag="KRH82_003819"
     CDS             complement(892..1302)
                     /locus_tag="KRH82_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657067.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(1518..2900)
                     /locus_tag="KRH82_003820"
     CDS             complement(1518..2900)
                     /locus_tag="KRH82_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBG8657068.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSSIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(2911..3270)
                     /locus_tag="KRH82_003821"
     CDS             complement(2911..3270)
                     /locus_tag="KRH82_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8657069.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(3475..4254)
                     /locus_tag="KRH82_003822"
     CDS             complement(3475..4254)
                     /locus_tag="KRH82_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBG8657070.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         1572 a          754 c          402 g         1778 t
ORIGIN      
        1 tatctatttt ttcttactat tcttatccac atcatccata tatttatttt acgattactc
       61 tttcactcta accctttaac tatctatttt ttctgatatt cttatccacc atcacccata
      121 tatttatttt acaattactc ttttacccta accctttaac tatctatttt tttctggtat
      181 tcttatctac tattatctgt atatttattt tatgattact cttttaacct accccctata
      241 ctttatagta atatgttttt aacctttttc attattccca atatgcttta taactacaaa
      301 tactctcccc ccttaaaaat aataataaaa ttaatcaata aatttataat catattatta
      361 ctctatgtat taagcaatta ctatgccaat aaactttgat ttttttaaac aaatcttaaa
      421 aatcctaaaa tgctaatttt ctttaacttt taatgaatct aatagataac atttaatttt
      481 cgttatattt ttcagaatat ttctattatt atttttaaga aaaaaaaata atgttaacat
      541 ttcttaacat acattaaaaa atgttaacat tataaattgg gtttaatact tttactttga
      601 ctcgatttac ttttattcta cttcttactt tatttttaac ttagacttta tttttttatt
      661 acttatttga gtcttattta ttttattctc actccatatg ttcaattaca tttgtctaaa
      721 ttctttgata cttttattac ataattttaa caagcttaag tgttatttgg gtagtgcagt
      781 tgataattat ttaaataatc atcaactgca tgtttatatc attacagtag cttaatgtat
      841 ttaatcatac ttacttagga ttttgaaata tcttagagat tatatttaac attagtcaat
      901 tgctgcataa ttgtaagcaa ttgaaatttg agacccatct tcattttcta tagtgatagg
      961 cttcataatt tttaatcctt cagtttttat cttttctaat tcttgttcca ttttcttaat
     1021 tgtttcctca aggtcttttt gacttacatc tttgactgca ttagggtctt tagcatagtc
     1081 ttttaattct tgaatatgtt tagcatactc ttcataagta taatgctcaa caccatactt
     1141 ttccaattca gtagggtcag ttattcctga ttttattaga gattcaaatt taggtaaagc
     1201 aatattagat gaatcatttc catttgcaaa tactgctcca gttcctccta gtaccattgc
     1261 agataccatc attgcactta taagggattt ttttattttc ataaccaatc ttcctttctt
     1321 agagatttat ttgggtagtg tagtttaaaa tgactattgc aatagttatc aactacactc
     1381 ttagactatc acagtagtca tgtttatgtc aagccttttt aaaaaacttt tcaataaaaa
     1441 atactatctc aaagcaaaat taattatttt gagatagtat tttaattcta aatcttttat
     1501 attactaaga tttatggtta ttctatccat gttctatatt gttctttatt aactgctaac
     1561 aaattccctt ttcttgatat gacaaagcga ttatcattat agccacttcg ctcaattgaa
     1621 acttctcctg aatcagtata aagtacatcc ttactattac tagatttatt tacatacgtt
     1681 tcttcactat tctcagaatt agttactttg ctcatagatg attcttcatg ctctctaaat
     1741 tcaattacag atacttttgc cgtactaaaa tgagtctctc catcactttt agctttacta
     1801 acaagaatat cagattctac tttgggagaa tataaatcag ttgatttact acttattgaa
     1861 aatccaattt tatcactttg ttcatttttt gttaaaccaa aagattcaac ctcattaatc
     1921 tctttatttt ctgttgcaaa aacaagacct gtcccacaaa ctaatacagt tgaaactaaa
     1981 aaagtaacat aagttgattt tttaaatttc ataatattaa ctattctctt ttctattttt
     2041 gtctttccaa atccactaca tattgtcatt gaaaatggat tattctcctc tgctagactt
     2101 attagtgtgg ttgcataatc agccctatat tcttcaccaa gtatactcat aaccttttca
     2161 tcacaactaa attctatgtc tttatttagt aaaaaaaaca tcacccaaac taagggatta
     2221 aaccaatgga caacaagagc tacaagcata aataacttta acagattatc aaagctatta
     2281 atatgaacca tttcatgagt taaaacaaag tctaaagttt gattattagc ataattcatt
     2341 tgctttggca aaataattcg tggttttaaa ataccagatg taagtggtgt cctagtaaat
     2401 tcagatatgc aaacaataaa tcttctaaaa cggctattct tacacatcca ttttttaatg
     2461 aactcatgat tttttatatg aattgaagtt ttaaaaagat taattatttt aaaatatcta
     2521 aagcataaaa gtatgctaaa cataatagta actataaaag acaaaatgcc caacatttcc
     2581 aacatcataa tattttcaat actagacatt atttcaaatt cgtcagaatt gtttttacct
     2641 gtagagtcac tagctttctt aagagtataa ttttctgttg atgtattacc caattccaca
     2701 tcaaaagtcg attcaattat actataaata ctaaaaccag aatttaaact tactggtatt
     2761 agaagtttaa ataaaacaat caaccacaat aatacaaata cctttttagg taatttttta
     2821 aataaacatg ctcttataaa aataactatt aaaagtaata ctccagaagt aaaactcatt
     2881 tctaacaatt taatgaacat aaatcttacc tcactttaat ttttcaacaa tttgtttaag
     2941 ttttgtaatc tcatcacttg aaagattttc tttattaata aaagctgaaa gaaatttttc
     3001 tgaagaccct ccaaacattt tattaattaa agtttctgtt tcctgttttt gtacttcctc
     3061 tttgcttatt aaagctttac aaacaaaatt cggctcaatt ctctctattg caccttttga
     3121 cactaatttt tttataacgg tatacgtagt gtttctattc catcctgttt cttcttttaa
     3181 aatttttact aactctccag ccttgctttc tcctctctcc catagaactt ccattacttt
     3241 aagttctgaa tcaaataatt ttatctccat ataaaatcgc tcctcaaata tagttatcac
     3301 aatagtcatt actataataa aaaactatca tagtagtcta tactatgtca atcatttatt
     3361 ttttaataat aaaaactgtc tttttaaaaa attcttataa aagacagttt tatcaatgtt
     3421 atactttaat gtttaattaa agccatattt tatttaaata tataactatc tatcttagta
     3481 catagtataa gatttttctt tatctaatag tatatcctct acatctgggt tttcttttac
     3541 taattgtcta taaaaattac aattagtaac acccacatat ggaattagcc atagtagacc
     3601 tattccaaga gtagctattg aaagtatata ccatcctata aagctaaagt ttagtacaaa
     3661 taatttaagt acatttcctt tcatcatatc taaactagca cccattgatt taaatacacc
     3721 catattatcc ttgtcttcac aaattaagaa agtagcttga gaaacatata atagcaatat
     3781 ataaactggt aacataagaa caagtattat aagaactaga gttattccag tagaaataat
     3841 agtccctatt ccaacattat cacttgataa atattcaatt gctccactag taagtaaaac
     3901 tccaaatgat aaaaacgctc ctataattgt gattataaaa gaataaatat acacaataat
     3961 tgattcaaat aaataaaaac caaaacttct taaataaatt ctcccactta caaagatatc
     4021 tcctatcttg actttttcat ctttagtaat tttcaagaac atacatgtaa atcctgctga
     4081 aacgcaaaaa gctattacag ccactacaat agtagtcaat ggttcaaaag gtaatcctac
     4141 aattgatatt aatactatca atgcaatata tactgccata gaaattgcac atatccccca
     4201 gtttccagat aactgagctt tagatactcg ttttaattct tgccttgata ccataaaaaa
     4261 cacccctttc attttataaa aaaactttta aaaatataaa taatctttta acgtataata
     4321 ttaatatatc atattttcga ctatataaga tacaattatt caccatgttt tatcaagata
     4381 tgccataatt gtattactag ttttatatag tcaacattac caaatacatc aaataaattt
     4441 gattaattat tcaacaagta ataaaataat ttctattaat tatactttat ttagtaaaca
     4501 aattat
//
LOCUS       DAEOTL010000165         4504 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEOTL010000165 DAEOTL010000000
VERSION     DAEOTL010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.167"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            268..1743
                     /locus_tag="KRH82_003823"
     CDS             268..1743
                     /locus_tag="KRH82_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBG8657071.1"
                     /translation="MDSEFANVVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1830..2243
                     /gene="speD"
                     /locus_tag="KRH82_003824"
     CDS             1830..2243
                     /gene="speD"
                     /locus_tag="KRH82_003824"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBG8657072.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2273..3124
                     /gene="speE"
                     /locus_tag="KRH82_003825"
     CDS             2273..3124
                     /gene="speE"
                     /locus_tag="KRH82_003825"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBG8657073.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3114..3992
                     /gene="speB"
                     /locus_tag="KRH82_003826"
     CDS             3114..3992
                     /gene="speB"
                     /locus_tag="KRH82_003826"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBG8657074.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4172..4372)
                     /locus_tag="KRH82_003827"
     CDS             complement(4172..4372)
                     /locus_tag="KRH82_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBG8657075.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
BASE COUNT         1800 a          501 c          760 g         1443 t
ORIGIN      
        1 aaaaaccaaa ataataaaaa ataagaaagt ttataaatac taagttttaa aaaaattaat
       61 ataaacaaca aaaaattaaa aagtttataa atattgatat agctaatgta tatgtttttg
      121 agtaacttca aaaaaacact tgtaaaaatg ctgagatgtt aatataataa atatcatgag
      181 tttaataaaa gtaaaaataa aaaatagaaa taataaataa taaatattaa aaatatttga
      241 atatagagag gagatgaatt tgaaatcatg gatagcgagt ttgcaaatgt agttgaatta
      301 agctatgagt gtgctccatt attagagtcg ttaaaggaat actcagagaa agatatagct
      361 tgttttgatg tgcctggaca tgtaaaaaat agaggtgtag ctatattaaa taaatatcta
      421 ggtgaaagtc tcatgaaaat ggatataaat tcatcaccaa ctatggataa tgtatctgcg
      481 ccaaatggga ttataaaaaa tgcacaagat ttgttagcac aagcatatat ggctgatgag
      541 gcattcttta taacgaatgg cacaactcaa gcaatacatg caatgatttt gagtgttata
      601 aaaccaggtg aaaaagtatt acttccaaga aacatacata aatcagtaat aaatgcgtta
      661 atactttgtg gaggaatacc aatatttata caaccagaat ttgatgaaaa actaggtata
      721 agtttaaata ttactcttga aaaagttaga acagagatag aaaaagattg taatataaaa
      781 gcattatttt tccttaatcc aacttactat ggagtttgtg cagaccttga gagtattata
      841 gaactatgcc ataaaaataa tgttttagtg ttagttgatg aagctcatgg tgcacatttt
      901 ccatttcatt tagatttacc tccttctgca ataagtttgg gagctgatat ggtagctgta
      961 agtatacata aaactggagg agcattgaca caatcttcag cactcttatt gaatagagat
     1021 aatgtaagtt ttgaaaaggt tcttcaatca atcaatatgc tacaatcaac atcagcatct
     1081 tatttgctta tggcaagtat agatggtgct agagttaatc tagttgagaa tggtgaaaag
     1141 caactgtcaa aagcattaaa tctatctagg tatgcaaaat ctaaattaaa caaaattgat
     1201 ggaataaaag ttttatctac agaaatattg aaacaaaaag gtgttaaatt tatagatgaa
     1261 acaaaattgt gtataaatgt aaaagaatta aatttgactg gatttgaagt atacgattta
     1321 ttatataaaa atttttcaat tcaagtagaa ttgggagatt catataatat actggcactt
     1381 gtgtccattg gaacaaataa atcagatata gatagattag taaaggcact ttctataatt
     1441 gcaaagattt atagaaaaga atcaacatta aatgaattta atatggttca aataaatcca
     1501 attattaaac ttaatccaag agaagctttt tatgcaccaa aggaaagtgt agaaatcaat
     1561 tcatgtatag atagaatttg tggagaatca ataatggcat atccaccagg tataccgatt
     1621 attgctccag gagaattgat aacagaagaa attatggagt atattatttt cttaaaaaat
     1681 agcaatgcgt atcttacaga tgtacaagat aaaaacttag atagaatact agtaataaaa
     1741 taaattactt tattttgcaa gggcaagtat ttgttaagta gagtttatca aatagaactt
     1801 attaaaagta taaaggagtt ggggttgaaa tgaaatttga aacactagga agacatatac
     1861 tagtagaata ctataattgt gatgaaaacg tacttaaaga cccacgtctt atagaaaatt
     1921 ttatgaatga ttcagcatta aatgcaaaag cgacaattgt ggattctgta ttccaccatt
     1981 ttaatccttg gggggtttca ggagctgtta taattgctga atctcatttg acaatacata
     2041 catggcctga atatggttat gcagcagcag atttttttac ttgtggtgat atagacccat
     2101 ggaaaagttt tgaattatta gagcaacttt taaagtctga aagaagcgag tctacagaaa
     2161 ttccaagagg cttaactaca aaaattaaaa aatattcaaa aaaagattta ggtaagatta
     2221 ctcataaacc agaagcagta taaaacatac aagagaaagt gaggattatt atatggaact
     2281 ttggtataca gaagaatgga cagaaaatgt aagattttct ataaaagtaa ataaacatct
     2341 atttgaagga aagtctcaat ttcaaaggat agatgtattt gatagtgatg aatttggaaa
     2401 atttctaaca atagatggat taatgatggt aacatataaa gatgaattta tataccatga
     2461 gatgataact catgttccta tggctacaaa tttaaacata aagaaagtat tagtcatagg
     2521 tggaggtgat ggaggtacag taagagaatt aagccgttat cctcaaatag aaaagattga
     2581 catggttgaa atagataaaa tggttgtaga tgtatctaag gagtatatgg atatatgctc
     2641 atgtaaatta gatgataaaa gagtgagttt atattttgaa gatggtgtta attttgttaa
     2701 gtgtgcacat gataaatcat atgacctgat aatagtagat tcaactgacc caataggacc
     2761 aggcgaaggg cttttctcaa ctgattttta taaggattgt tatagaatac tgactgatga
     2821 tggaatttta gtaaatcaaa gtgaaagtcc gtattttgac tttaatgcta aagagatgaa
     2881 aagagctaat aaaaaattaa aacagatatt tccaatatca gaagtttatc aagcacatat
     2941 accaacatat ccatctggtc actggttgtt tggatttgct tcaaaaaaac ttaatccagt
     3001 aaaaaatcaa gatagaaatg gatgggagaa attaagttta aaaactaaat attataatag
     3061 tgatatacat ttaggttcgt ttatgttacc tcaatacgtg aaggagatgc tagatgaaga
     3121 ataatttcta tcatatgaac acttttatga gtatggacaa aaattatgaa gaatctaatc
     3181 ttatagtatt tggtgttgga tttgatggaa ctacttctaa cagacctggg gctagatttg
     3241 caagtagctc tatgagaaaa gaattttacg gtcttgagac atatagtcct tttttagatt
     3301 tggatttaga ggattataat atatgtgatt atggagattt agaaattagt gttggaagta
     3361 cagaacaagt cttaaaagaa atctatcaag agacatataa gattgttaga gattcaaagg
     3421 taccctttat gattggagga gagcatttag ttacattacc agcctttaaa gcagtacatg
     3481 aaaagtacaa tgatatatat gtaattcatt ttgatgccca tactgatttg agggaagaat
     3541 ataataatag taaaaattct catgcaacag taattaaaag aatatgggat attgtaggtg
     3601 ataataaaat atttcaattt ggtataaggt ctgggacaaa agaagaattt aaatttgcta
     3661 cagaagaaaa acacacatac atggaaatag gaggaataga tacgtttgaa aatatagtta
     3721 atatgctaaa tggaaagaat atttatctaa ctatagattt agatgtattg gatgcatctg
     3781 tgtttccagg aacaggtaca ccagaacctg gtggtgtaaa ttatagagag tttcaagaga
     3841 tttttaagat tataaaaaac tctaatataa atatagttgg ttgtgacatt gtagagttaa
     3901 gccctgatta cgatacaaca ggtgtatcga cagttatagc ttgtaaaatc ttaagagagt
     3961 tatgcttaat aatatctgat aaaattaaat agagtatttt atataaatag tatatattat
     4021 aatataagaa gttattttaa aaaagttagt ttaagtttga cgcttttcta aagtaacttc
     4081 ttatttttgt aattaaaaat aaatataata aacaacaaaa aagagccctc gatagctcct
     4141 tttctaaaat atatatattt aaattaaata attatattct atttacgttt tcagcttgag
     4201 gtcctctatt accttgagtt atatcaaagc taaccttttc gccttcttct aaagttttgt
     4261 atccatcatt ttgtatagct gagaaatgta cgaaaacatc atcttctccc tctacagata
     4321 tgaacccaaa tcctttttca ttgttaaacc attttactat tccgtttttc attataagaa
     4381 aacctccgca ttattaaaaa atacaaacta aaaaaataag tctgttctat taatataaca
     4441 taaattttaa ataaaagcaa ataaaatttt taaaaaaatt aattactttt agaatttaat
     4501 aaaa
//
LOCUS       DAEOTL010000166         4432 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEOTL010000166 DAEOTL010000000
VERSION     DAEOTL010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4432
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.168"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            31..699
                     /locus_tag="KRH82_003828"
     CDS             31..699
                     /locus_tag="KRH82_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657076.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKGEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            858..1364
                     /locus_tag="KRH82_003829"
     CDS             858..1364
                     /locus_tag="KRH82_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBG8657077.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            1492..2508
                     /locus_tag="KRH82_003830"
     CDS             1492..2508
                     /locus_tag="KRH82_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBG8657078.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2861..3565
                     /locus_tag="KRH82_003831"
     CDS             2861..3565
                     /locus_tag="KRH82_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBG8657079.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLGDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            3860..4339
                     /locus_tag="KRH82_003832"
     CDS             3860..4339
                     /locus_tag="KRH82_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBG8657080.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT         1856 a          373 c          760 g         1443 t
ORIGIN      
        1 ttaaataaat tttttaaagg gtgatttttt atggaaaata taactagtta ttttacaaca
       61 atactatgtg tatttatatg cttatcatct gtatttatat ttactcaact agctagagta
      121 tttattaata agaagaagat taatcaaaaa attaaatcaa gaaacggatt taggtatgat
      181 agagatttta ttgaagccag aagagaagaa atacatataa aggataacaa taataataaa
      241 aataagagta acaataagaa attaaaggga gaaaaagtat ttaaatacga taatggtgat
      301 ttatataaag gtgagtttgt tgatggaaag aaaaatggat ttggaatata tattttttca
      361 agtaaggaaa agtatgaagg attatggaaa gatgacaaga tgcatggaat aggaaaatat
      421 acttatagag atggttcaat atatacaggt gaatttaaat acggattaaa aaatggtttg
      481 ggaaaattaa catatcccaa taatgacatt tataagggat attttttaga taataagaaa
      541 aatggtaagg gtgtattata taaaaatgat ggaaataaac aagcaggaat atgggaagat
      601 gatgaacaat gtaaaagttt agattttaaa gatttaaata ataataaaat aaataatgtt
      661 tatcaaaata gattaaataa caataaatta aaagtttaat tattctaata aaaaaatctt
      721 tatttatgat ggaatatagg atatatctat gttgtaattt gtaaaatctt cctatatcat
      781 ataaaattaa gtattgatta gtctattaca taaatataga atataaatat atccatttaa
      841 taataaggag aagagatatg aaagagtatg tagttgtgga tttagaaact acaggattag
      901 atccatataa aggttgtgaa ataatagaaa taggaataac agaaataaaa aatgaacaaa
      961 ttgtaaaaaa ctattcaagg ttgataaaac ctaaggggat aatttcttca tttataacag
     1021 aattgacaca tataagtaat gaaatggtag aaaatgaaga accactagaa ttagttttac
     1081 ctagatttag aaaatacata ggtgatagaa ctataattgc acacaatgcg aaatttgatt
     1141 taaaattttt aaattactat cttagaatgt tagatttaga accaataaac aattatatat
     1201 gtacagtaga gttattaaaa aaatgtaaaa gttataaagg aaaaaacaag aaacttgaaa
     1261 cagcttgtgc ttattacaac atagagaata taaatgctca tagagctgac agtgatacat
     1321 tagcaactgc aaaactattt ttgaaaataa aagatgaata ttaattataa atatagagaa
     1381 aattagtgaa aatatccttt ataaaattga cccttaagct tacaattttg ttctttgatt
     1441 tattttgtag aacaatgtat aatgtacctt atatgaagaa gggagactaa aatgggttat
     1501 tacaatgata atgataataa taaaataaga cgtaaaaaaa ttagtaacaa caaagatagt
     1561 aataaaaaat ctaaacattc ttatacttcg gcaaataaaa aaaataaaag tcctaataca
     1621 agttccagta aaagaatgag tgaaaaagta gattcacaga atcttataaa aagagataga
     1681 gatagtttta caagagataa tgtaagacct ttaaatacag attacaatca aagagaaaga
     1741 agaagagtcg agtataaaca aagagagaaa aaattaaaaa gtaaaaaaag aaaaaaacaa
     1801 aaaaggatta gaatagttag ggcattatta tctattatgt tagttgcact aattatattt
     1861 tcagtggcag gtgcaatatt tacagtttca gctataaaag ggtcaccaga agttactaaa
     1921 aagttaatta ggtctaaata tataagtagt gaggttgtaa gtataaaaca aatgccaaat
     1981 gatttaaaac atgcaatagt ttccatagaa gatgagagat tttataagca taaaggagta
     2041 gatgttattt ctctagttag gtcagtatta aacaatgtgt ttacagatac aacacaaggt
     2101 gcaagtacta tagatatgca agtttcaaaa aacctgctta ctagtaatga taaaactatg
     2161 aagcggaaaa taagggatat gtataatgct aagcagatga ataagattat gactaaggat
     2221 gaaattcttg aagcatattt aaataatatg tatctaggta aaaatgcata tggagctgca
     2281 aagggagctg aagtctactt tggtaaaaag gttagtgaat taaatttagc tgagtgtgct
     2341 atgttagctg gtatgacaaa taatcctgca aggtatattg accatggaga ggctaagaag
     2401 agacaagtga ttgtgttgta taagatgcat cagcttggtt atataactga taaggagtat
     2461 agaatagcaa aagctgatga cactccattt aaatcagaaa ttgattaaaa ttgtaagaat
     2521 atagtatttc aatagtttaa acaaacgaaa atgtaataaa aaaggtgatt tgccacccat
     2581 ttgccaccat aattataatt taatagcaaa ttgttttaat gtacaaatcc gataatataa
     2641 tattgtttta aatactacat tatgctaaaa tttaattgta ttttgtaaat taaaaaactt
     2701 ataatttagt tttctagggt tccgcatttt ataatggtca ggtccaagag aaaacgcaca
     2761 attgttgtgt acacggaagg ataaaagcct gggagatatt taataatatt tctataggct
     2821 tttttatttt tacatatttt aaatttgagg aggttttcta atgaaaaaat ttgttattga
     2881 ggatgcattt tggaatctat ttcctagtgc aaaaattgga gttgttattt gtaatgatat
     2941 agataactct ataaaagatg aagactataa gaaaataatt ttgaagggag aagaagaagc
     3001 attaaaatac ttgggggact cagaatttag caacaaccaa gtgattaaag tatggagaga
     3061 agcatttaaa aaatttaaaa cgaaaaaagg agcaaggtct tctattgaag cattattaaa
     3121 aagagttcat aatggaaata atataggaac tattaaccct ttagtggata tctacaattt
     3181 tatctcatta aaatatgcat taccttgtgg aggggaggat atagataaat ttataggaga
     3241 tattaggcta actagagcaa ttggtaatga ggagtttatc ccactaggga cagatgaaaa
     3301 ttcatttcca tatgaaggag aaataattta taaagatgat ggtggagcaa tttgtagatg
     3361 ttggaattgg cgtgaagcag tgagaacaat gcttactgaa gatactaaca atgccttttt
     3421 atgcattgaa ttagtagatg aaagtagatt taaagaattt gaaaatgctt taaatgaatt
     3481 agctaaaata gttcaagaaa aattgggtgg gaattgtaaa atttcaattt tagatattga
     3541 taataaagag gtatcagtgg attaatatgg aggtgctgtt gtaatggact attctagtta
     3601 taaagatact tatatttagg gtaagaaggt ctattttaga tataacgatt atcaaaggat
     3661 ataatataga aaataaaaat gtagaatata aaaagccttt aaaataagaa aaaaatgtat
     3721 tttaaaggct tttattatac tcttttttat ttgcataatt aacaataaaa atatattgtt
     3781 aattataata tttttattga aaaacgatat aatataatgt attatactat atataaaata
     3841 ttttaaagga gttggcatga tgtctaataa acttataaaa aatttactaa gtggtatatt
     3901 acaaatttta ttttttcttt taggattagt aattgttgca ggaggattta aaagttttat
     3961 gtacctctgt tttagtggag aagcaactct acaaggtact atttatggaa tattaatgtt
     4021 tattttaggt gtatcatatt ttatcattat aaaatcattg atagaagtat taggtagttc
     4081 tgaatatagc ctatttgtaa aagagaatgt aaaaagattt aggattattg gatatctttt
     4141 gcttttaaac tctctaattg agtttatttc aacttttggt actactggaa aaggaatgag
     4201 atttctagat ttaggatttg gattttattt tactgttcca gtatttgtat attttataac
     4261 ttctctgatg agttttgtaa ttgcagatgg atttgtaaag gcaataaaga taaaagagga
     4321 taatgattta actatttagg tgtgacactt taatatatag gagataaata acccgaaaag
     4381 agtgattaac tagtaattta aaatatatta gggtataata cataaactat aa
//
LOCUS       DAEOTL010000167         4353 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEOTL010000167 DAEOTL010000000
VERSION     DAEOTL010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4353
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.169"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..857)
                     /locus_tag="KRH82_003833"
     CDS             complement(<1..857)
                     /locus_tag="KRH82_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBG8657081.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITV
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCQNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKYTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLMQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHS"
     gene            complement(854..3064)
                     /locus_tag="KRH82_003834"
     CDS             complement(854..3064)
                     /locus_tag="KRH82_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8657082.1"
                     /translation="MKERIKGAFTKKKIFHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTANGFSSSGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGADRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLFIFNIGITIFVFLLM
                     GIMMLSQILFIIFAMFLPISFLLSMIPSQENLAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISKDYPFFMVAFLQIVCFAGIFIKLGDLMNMFSLNAGDSQNMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRAERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQRRQNIADKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTIPKPSVEKMQEVKRPATATTSKISEPVKTSVIKERPLSSGASDRKASQPIQP
                     AHRQNVEKVVSQETHQNYKAERTTKAQTFEQSKRTTEHTEKNRNLVMKKGQKKK"
     gene            complement(3064..>4353)
                     /locus_tag="KRH82_003835"
     CDS             complement(3064..>4353)
                     /locus_tag="KRH82_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657083.1"
                     /translation="DMLGLHSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETT
                     GIYMGYSVDTGRNVYLQPSLASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVL
                     FGGQALLLDPKSERGNWKETLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESL
                     AIDILTFLTGISSRDGEKFPVLRKAVRSVTQSDSRGLLHVIDELRREDTPVSRNIADH
                     IDSFTDYDFAHLLFSDGTVENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVS
                     MLIVISTFALDFIHSDRSIFKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFV
                     TQSSGDVAKESLKNNIGLKFAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQC
                     LLQDLYGRVGVVQIHPVFEELLHAFDTRPPVQRNEVE"
BASE COUNT         1123 a         1071 c          895 g         1264 t
ORIGIN      
        1 gaatggaaaa ataccaagtc cccagccttt gcctgcgaaa gcggaagatg ttgggtagcg
       61 tcatattgtg cttgtgctgt tctcggtaag gagataccag cttttccata acaccattgc
      121 atcagtcccg agcagtcaaa ggaagtgttg ggattgctac cgccatacac atacttccag
      181 ccttgatatt tcaacgcttc attcattacc ttttgtgcca gctctcccga tacctgcgga
      241 acagttaaat actgattgac taattccaca tagaacatat ttccatagcc ataccgccag
      301 cccccgttct ttgcaacggc tatcgggttg gtgtaggtta ctttctttcc acccgatttc
      361 tcacgggcga agctctctgc aagattaaag gtatatttct ttccttttcc tgccacatat
      421 cccacataac caccgccata attataggac tgtatcgcta cattcaagtc gtcgatacct
      481 tgattttggc aggaagaaag cagggacgca aaatatttac acccctgctt gattgaactt
      541 tcggtatcta aagagttggg tggtagtccc aaactttccg aactctgcat aacatcttct
      601 gccgtaccgc cactttctac ttgaataata gcaagtagca cattgacata ctcggagata
      661 ccgttttctc tggcgtattt ttccaccata ggctgatgtt tcaaaacttc tgcggataaa
      721 ttcataaccg taatgccaga agaaaagttg ctgttttcgt cgtcgctgtc cgcactaatg
      781 aggacaccaa agaacagcac cagagaaaag aggataggaa acagactgcc aataagagcg
      841 atatgtttca gtttcatttt ttcttctgtc ctttcttcat tacaaggtta cggttctttt
      901 cggtatgttc cgttgtacgc tttgattgtt caaaggtctg tgcctttgtg gtacgctctg
      961 ctttgtaatt ctggtgtgtt tcctgcgata ccactttttc tacattctgc ctatgtgctg
     1021 gctgtatagg ctgggacgct tttctatcag aagcaccaga agataacgga cgctctttga
     1081 taacacttgt cttgactggc tcacttatct ttgaagtggt cgctgtggca gggcgtttga
     1141 cttcctgcat tttttccaca ctcggctttg gaatggtcga agctgtggct ggtcgctcat
     1201 ggggacgggt agctcccgtt gtcgctgatc cgtcagcctt tcgctgtgcc tgccttgctt
     1261 cttgtgcttt ttgaagctcc atacgcttgt cagcgatatt ctgcctgcgt tgctcctgct
     1321 tttccaatcg tcccgtctgt ctggactgct gttcctgcac catgccacgc ttgaaatctg
     1381 atacgctgga ctttgccttt tcctttgcgg aatataccgc ataagcggtc tgtgtcggca
     1441 tatccttgat gttttctttg acagcgtttg ccttgtcttt cactttattt ttcgtatcta
     1501 agacagcacc cacctttgag cctgctcgct gtcccatgct ggaagtggta ttgccccgat
     1561 tttctttaga agctgtattt tttctttccg ctcgtttgcc agcaacggca cttccagcca
     1621 ccgcaccagc cacaccaccc gaaataccgc cagcacttac tgcccttgca atacggtgtt
     1681 ccatacgcct agctctatgt cgcataaaca gatacggtct gcggaatatc ctgcgtccca
     1741 tattttgact gtcgccagcg ttcaaagaga acatattcat taagtcgcct aacttgataa
     1801 agatacctgc gaaacacact atctgtaaga acgccaccat aaaaaacggg taatctttgg
     1861 agatgttata aaacatactg gaaatactga acgccaccgt tacaatgagc gttattcctg
     1921 cccgtgtcat tatggtatta aacaccctca cgattgcctg ctttgccaga ttttcttgac
     1981 taggtatcat ggaaagaaga aaactgatag gcaaaaacat tgcaaagata ataaaaagta
     2041 tctggcttaa catcattatc cccatcagta agaatacaaa gattgtgata cctatattaa
     2101 aaatgaatag gaagaacacc atacccaagc ggtttaccac ctgcggtatc gtcagattgt
     2161 tgttgtcgtt atcctcgatt tctgttttca cgacttcctc tctggtcttt ccgtcctcgt
     2221 cctctgggct tgccgataca agagcttcta cacggtctgc cccgatttct tctgcgttgc
     2281 tgttcccgaa ttgtaagagt aaccacggct gttccacttg aatagaaaat agactgtccc
     2341 gtatcaagtc tacgctgtcc ttgccctcgc tgtcagagtt tgggagcatg atttttgttc
     2401 ccaagtcaag tgaagcggta ctgatgtctg atgaaaactc atttatcttc ttgatgtagt
     2461 cgggagcata ggcaataaac gaagcggaca gcacgaacac caccacaaag ttgataacgg
     2521 catgaagtgc tttactggtt tcccgtttga taagtcccgt atatgcaaca taaagtccca
     2581 ccactaagat aatgagaagc aggaaaccaa catagaagcc agagctggaa aaaccgtttg
     2641 ccgtaacacc tgcaagggtc tgtatgcttt ttccgatact gtctgccata tcgttaataa
     2701 aatcaagttt gtaggcttcc tgcaccacat agcccgtagc attgcttaaa tataggctta
     2761 tcgtccagac aaagttggta atgcagtaaa gcccgtactg caccgatttt ccgataccgt
     2821 ccagccagtt ccacggaagc cacgaccagc tattatccac ataaaaatca agctggtagt
     2881 tggaaagggg atattttgag taaagatttt ctgcgtttat ggtatcgtcc acaagccccg
     2941 tcgcatgagc caccgtcccc aaaagtgaaa gcaggataag ggagagtgcc accacgaaca
     3001 gagccatttt aagaaagtgg aaaatcttct tttttgtgaa cgcacctttt atcctttctt
     3061 tcatcactcc acctcatttc tctgtacggg cggtcttgta tcaaaggcgt gtagcagttc
     3121 ttcaaaaacg gggtgtatct gcaccacacc gacacgcccg tataaatcct gtaataaaca
     3181 ttgtccgttc tccaaatcac gcaagcgttt ctggttattt tcgtcgtcct tgtcaatgcc
     3241 gaaaaattct aaggtctgct ttatctcgtt gatgtcagta gaacgaaagg caaacttcaa
     3301 gccgatattg tttttcagac tttcctttgc cacgtcccca gaagattgtg taacgaaata
     3361 aacgcctgcc tgcatagctc gtccagcacg aaccagcttg tttgataagg tttcgccttg
     3421 tgccacattt aagaacgccc acgcttcgtc aaggtctaca atcttaaaaa tacttctgtc
     3481 agaatggata aaatcaaggg caaaggtact aatcacaatc agcatagaca ccgacaataa
     3541 ttcaatggtc gtgtattcct caaaagttgt gtccttatct ggcaacacaa ggtcagctac
     3601 ttgaatgata ttgagctgat tatccagact gatagcattt tccaccgtac cgtctgaaaa
     3661 cagcaggtgt gcaaagtcgt agtccgtgaa gctgtcgata tggtctgcga tatttcttga
     3721 tactggcgta tcttcacggc gtaactcgtc tatcacatgg agcaagcccc gactgtcgct
     3781 ctgggtaaca gaacgtaccg cttttcgtaa cacgggaaat ttttcgccgt ccctagagga
     3841 aatacccgta aggaatgtta agatgtcgat tgccagactt tcagcgtcct taacattctt
     3901 cataatcacg aatgggtcaa gaagtcctgc attgtccttg tcgcttgtta ggtttacgat
     3961 attgatttca tgggcgattt ctgggagcgt ttctttccag ttgccacgct cacttttagg
     4021 gtctaacaga agtgcttgac cgccaaacag caccgaataa tacaccagaa gattgttaca
     4081 gaacgatttc ccaccgccaa gcgaaccgac aaaagcagac gctaaagcgt tggtaactgt
     4141 accttttaca ccttgactgg caagggacgg ttgcaggtac acatttcttc ccgtatcaac
     4201 agaatagccc atatagatac ccgtagtttc tcctaactgc tgggtagcac caaaaccaag
     4261 ccctgctaga aaatctgatt ttacatactg cacataatca ttgatatatc gcttgctggc
     4321 aggaagaaat tctgaatgaa gccccagcat atc
//
LOCUS       DAEOTL010000168         4285 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEOTL010000168 DAEOTL010000000
VERSION     DAEOTL010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.170"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            224..1303
                     /locus_tag="KRH82_003836"
     CDS             224..1303
                     /locus_tag="KRH82_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBG8657084.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEDRMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRRH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1627..1995
                     /locus_tag="KRH82_003837"
     CDS             1627..1995
                     /locus_tag="KRH82_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBG8657085.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2112..2909
                     /locus_tag="KRH82_003838"
     CDS             2112..2909
                     /locus_tag="KRH82_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBG8657086.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKLLRNIISK
                     MCGDTSEGRRSMMKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            3308..4198
                     /locus_tag="KRH82_003839"
     CDS             3308..4198
                     /locus_tag="KRH82_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBG8657087.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFDAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVFKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
BASE COUNT         1638 a          479 c          806 g         1362 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaatttat atagtttaac agtaggaaat atcgtatgag
      121 taagactatc gtattttaca taaagattta gcaatatgac acactgttgt cgtgttctgt
      181 agggtatgat taataaatca gatatgaaag gagagtgagt aatatgccag aattactaaa
      241 aaatatgtat aatcgtgagt cactttatga agttgcagta gctatccaat cagtttataa
      301 ctcatttaag gtagacgagt tcataaaatc tacaatggat gagacatgga ataacttaga
      361 attaaaagcc agatgtcgaa agataagtat gagtttagga atgtatttac cagaagacta
      421 taaggaagct ctttccattc ttgaaaaatc agttacaggt ttttattttg cttttttctt
      481 tccagatttt gttgaagttt atgggcagga cgacataaat tgggatttat ctataagtgc
      541 attagaaaga aatactgagt attggtcttc agaatttgct gtaagagcat ttatcatcaa
      601 ggatgaagat cgtatgatgg cacagatgcg taaatggtct aagcataaga gcgaacatgt
      661 acgaagactt gcaagtgaag gttgtcgtcc ccagttgcct tggggacaag caatatccaa
      721 atttaaaaaa gaccctacac ctgtactgcc tatattggag caacttaaaa cagatacatc
      781 aacgtatgta caaaagagtg ttgctaataa tctaaatgat atctcaaaaa cacatccaga
      841 tttagtcata agcattgcaa aggattggta cggtaaaaat aaatccacta actggattgt
      901 aaagcatggt tgcagaactc tgctaaaaaa aggcaatcgt gatgtattag ccctttttgg
      961 atatgatgat actacttcta taaatcttca ggactttact ttagaaacaa cgtctatttc
     1021 tattggagag gatttaactt tttcatttaa tattttagca aaaaaagcga caaaaacaag
     1081 gctcgagtac ggaattgatt atattaaatc taatggaaaa aggaatagga agatatttaa
     1141 aatatcggag gtttcattaa aagaaaatga gaaaaagtca tatatgaaaa aacattcatt
     1201 tgcagatgta agtgtaagga gacattatcc aggcatccac tcgattgcta ttattattaa
     1261 tggtatagaa aaagataaac ttgattttga attaggtata taattttact aacagaataa
     1321 tctatatcag atactttgct aaacttatat aatatatttt actaaattta tattaggtag
     1381 tttactactt gtttactgaa tttaaataca aagaaataca ggtgttaatc cctgcccatt
     1441 aaaggaatat gagcataaca caaaagtaga acttatcaat tctgttacaa gtacagtagt
     1501 aaatcctcat aatcacaatt agcaaatgaa gtgtaaaaaa taagttagtg ttgattttag
     1561 ttgctagtga tattgaatag ttatacaata gccatataaa ttagaatttg tagaggagaa
     1621 atgtaaatgg atgtatatag tttttggaat gacactttgg cacaagatgc tgttaagata
     1681 agaaaatatt ttcatgaaga tgcttatatt aattggcatg atacaaatga gcattttact
     1741 ttagaagaat ttattattgc aaattgtgag tatcctgata aatggaatgg taaagtagaa
     1801 aaggtgctag aatttggaaa tttagtaatt acagtgacac atgtttatgc aataaataaa
     1861 ccactatcat ttcatgtcgt ttcatttatc agccttaaag atgataagat tatttctatt
     1921 gatgaatatt ggggagagga tgatgatgtg ccacagtgga gattagataa acatattgga
     1981 aagccaataa aatagtgttt gttctgtttt ataactgaaa ttttgataac atttgatact
     2041 ttgatttgtc attggtcaac atagtcgtta gtgtaataat ttaaaaaagt agaatttgga
     2101 gagtgagcac tatggaagaa aaatacatct tatctgaccg aggtaaagta tattattgga
     2161 taaaagaaag taatagtgtg tttgcaaaga acttaatttt tttgccagga ctaacagcaa
     2221 atcatcatct ttttgatttc caaatacagt acttttcaaa aaatcataat gtattggtat
     2281 gggacgctcc tgctcatgga aaatcaagac cttacttaga tttctcatat tctaacttgg
     2341 tagaagaatt gaaagtaatt ttagataaac aaaatatgaa aaaggttgta cttatagggc
     2401 aatcggcagg gggatttgtg gcacagtcct ttattgtaaa atatccaaat atggtagaag
     2461 gattaatgat gattggaact tgtccatatg gaactgacta ttatagtaag tcagatattt
     2521 tctggttaaa acagactgaa tggatgttaa agttattccc agataaattg ttgagaaaca
     2581 taatatctaa gatgtgtgga gatacgtctg aaggcagaag gagtatgatg aaaatgttag
     2641 aaggctacga aaaaaaagaa ctgtgtcatc tcatgtatct gggatttgct gggttcatac
     2701 cagaaattca agacttaaat atacattgtc cagtttgttt ggtggttgga gataaagaca
     2761 agacgggtaa agtgagaaaa tataatgagc agtggcacaa taagactggg tatccattgc
     2821 acattataaa aaatgcttca cataatgtaa atgtcgataa acctaatgaa ctaaatcaga
     2881 ttatggatat atttattaag caattataat atataaaaat tacataccca ttaggtaaat
     2941 tatgtagtat atgtgtttac agatggttat agaaataaat atgtaataaa ctacttaaca
     3001 cttaaaaagt ggatttgtcc agagcataat acaaagcatg atatatataa atttttaagc
     3061 gaaatacatc aaaagaagga ttagaattag tggagacaga acagctatta tagattataa
     3121 ataaatagtt ttaaaggatg ggtactacga atatagagga aggtaaatca tacgttattc
     3181 aaggattata aatgattagt ttaaaagtac tatcggatag gagtctccat atttaaacct
     3241 tagtaaaggt agttaaagta gtagtttaaa aactaaaaaa ttatataaag gaattaggta
     3301 taagaaaatg attgagagta taccagcaaa acaaatttta caaaaagtga aatttgacaa
     3361 tacaagatgg tttggaattg actataatat gaatctctat cgtggctgtt ctcatggatg
     3421 tatatattgt gatagccgta gcacaatata caacatagag aattttgaca aagttagata
     3481 taaagaaaat gtgatagaaa ttttaagtaa agaattgcgt tcaaaaagaa aaaaaggggt
     3541 agtaggcatt ggagctatgt ctgacacata taatcctttt gaaaagcaac tttgtattac
     3601 aaagcaagca ctagatttga tttcggaaaa tcattttgga gtatctattg atactaaaag
     3661 tagtttggtg gttagagata taccgatttt gcagaaaatt aaaaaaaata attctgctat
     3721 tgtaaagttg actataacca ctgcaaatga tgaattatca aagaaaatag aaccttatgt
     3781 aaatccaagt tctgtacgat ttgacgcagt gaaagaactt aatgattctg gaattttttg
     3841 tggcatatta ttgactccta tgcttccatt tttgactgat aataaagatg aaatacgagc
     3901 aattgtagaa aaagcacaca aggctaatgc aaaatttatt tattgcatgt atggcgtaac
     3961 aatgcgtagt ggtcagagag agttttttta tgagcattta agagatatat caccaaaatt
     4021 ggtatttaaa tatcagaaaa catatggttt aaactatgta tgtactgtac aaaataaaga
     4081 ttgttgtgag aagttgttaa gagaagaatg tgcacgttat ggtattttga cggatatgaa
     4141 agagattata aaagcgtaca agaggtcgga gtcatatatt caaataaaat ttttttaaga
     4201 taggctttgg atgagatata atagtggtga ttgatgtgtt gatattatag ttgattgtta
     4261 gagaggatat tatagatgaa tatta
//
LOCUS       DAEOTL010000169         4114 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEOTL010000169 DAEOTL010000000
VERSION     DAEOTL010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4114)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4114)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4114
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.171"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..613)
                     /locus_tag="KRH82_003840"
     CDS             complement(<1..613)
                     /locus_tag="KRH82_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBG8657088.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKLMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIF"
     gene            complement(1144..1521)
                     /locus_tag="KRH82_003841"
     CDS             complement(1144..1521)
                     /locus_tag="KRH82_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8657089.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            complement(1708..2679)
                     /locus_tag="KRH82_003842"
     CDS             complement(1708..2679)
                     /locus_tag="KRH82_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8657090.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            complement(2713..2910)
                     /locus_tag="KRH82_003843"
     CDS             complement(2713..2910)
                     /locus_tag="KRH82_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBG8657091.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAIFSPI"
     gene            complement(2978..>4114)
                     /locus_tag="KRH82_003844"
     CDS             complement(2978..>4114)
                     /locus_tag="KRH82_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBG8657092.1"
                     /translation="EKCKELKNNILGFDFLYSIKTNPYNKIVKSIAEQGFGADASSTN
                     EVMISSKCGVSKDDIYYSSPGKTEIDIETVLDKCIIIADSITEIELINKISKKHNQKV
                     KIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVFKMLSMCDYVSVVGIHIHIKSQVLDF
                     EKLGHYYEKCFFIALNLNKSKYINIEFINFGSGLGVAYDNLRENPLNLKELSKLTQKI
                     AFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVDIKVSRGKKYLIVKNGLNGFMRPIIS
                     NLIENITCGVELEGQEPLYTSNHAFSLSVLNNLKEEEYVNVVGNLCTSLDVIANNIKL
                     KKANIGDLISISNAGSYSYSLSPLLFSSYEFPKQYYKRKDGYIE"
BASE COUNT         1524 a          620 c          425 g         1545 t
ORIGIN      
        1 caaagattga aatgttagat aatattaata gtaaaactat tactaaaaaa gcagttcttc
       61 tttcaggaga gatttttaca agattaataa tataatcata aagtacaaaa aatgacaata
      121 aatttgctat cataggaata catatgtata tctctttttt acttatttta aaatttttaa
      181 aagaagcctt ataaacataa agtaatatac ctaacattag ctttcccaag aatattgctt
      241 catatctata taaactgcca ctaagtaaaa cattcatatt atccaaattg cttactgttg
      301 ctactaataa catacttaat ccatttatac ctattaatat taaccaataa aaaaatgaga
      361 ttaccagaca tttatatata ttaaccttat agttagactt atagaaaacg aacattacaa
      421 atatacatat caatattcta ctattagctc ctatatttat atataaagaa gaaataatga
      481 gaaaaacaga aaagagaaaa tacatattta gtttttttaa gtcggtcttt gactgactag
      541 tataatcaaa aactttttta catgaccata tttctataat agaagaaaca attgttataa
      601 atgcatctaa cataataata tcctcaaaaa tgattaaatt atatttttta taaaatatat
      661 cataaaaaat acatactaat tatagcataa aaaacacact taaatttaat ataattattt
      721 aatattttta acaactttct atagtacatt ttaaaatatt tacagataag ttaccaataa
      781 taaagtttaa aaatataaaa atcatttctt acttttagtt tacctataat aacaaaagac
      841 aggtttatat tgtaataatt aaaaatagta aaatatattt tgatatggtt aaatagaaat
      901 aatactttag attaatgaat attgacaagt tataaaatta ttttaaattt taaaaatcat
      961 ttcttattta aataagtggt atcatttaac ttgatactcc ctattccaat tattttaggc
     1021 attttactaa ttagagaacc tatttaatat tactttatga atagtgagta gctgattaaa
     1081 taataccatt tatggttttc agccatagat taattaaatt cttagagttc tatcctgata
     1141 taattactct tcttctaaat ttttaaaatg actttcaaat aaatccaaca tatctttatc
     1201 aacaacttca tcatcatgta gtgctgaaat taaactctgt aaagaattgt cgtgtatatt
     1261 gcttaaaaaa tcttttgtct caacacttaa atactcctta tgtccaacaa ctattgtata
     1321 atgagtgtat ctatctattt tttctgcact taaaaaatgt tttttaacaa gtcttgataa
     1381 aagtgtcaat gtagttgttt gtttccaacc atattttcgt tccatagctt caatagtttc
     1441 ttttgatgtt actgtatcat ttttttccca aataaacttc ataactttta attctgcttg
     1501 tggtattttt gaaattgtca taaccttacg cccctctcaa acttttatta aattaatact
     1561 atcgcaatat agtttttaag tcaaagattt tgtcgataat aatattttcc aatttttacc
     1621 atagggttat tttttatata attttatgat aaattacata aaaaatattt attttacatc
     1681 ataaaattag aaatgtaaat agtatgatta tttagtctta tctttaataa acaatccagt
     1741 aaatttatac atccaaagtg cattcataaa caacaataaa cttgttgaaa aaaatactgt
     1801 tctaatacct aaatgtgctg atatttgtcc ccctaaaaat gctcctgatg aacagcctat
     1861 atactgggca gatgcattat atccaaatat ttttcccaca tattcttctg gtgcaatttt
     1921 tttaagcaag ctgttaacag aaggattaag ccctgcaact gacaacccta ataaaaatct
     1981 caacaacatc agttgccatg cagtttttac aaaagcttgt ggtataaata taatcccagc
     2041 ccataaaagt gaaattaaca atactttttg agggcctatt ttatctgaca tttttccaag
     2101 tttttgagct gctaataaat ttgctaatcc tgatgcagaa aatgtcaatc cagctattaa
     2161 agctacattt gatgcaaaat ttgtaagttg tgatatatat atggttacaa ttggttctat
     2221 agagtataaa gctagttgag taatgaatgt ggttacaaaa atagatgcaa ttaaaaattt
     2281 atttggcaat atatttaatt gttctttagg tatagaaatt gattctttta tttctttagg
     2341 tttaaaatta tctactacaa ataaaataga gatgataaat gatacaaaca acaatcctcc
     2401 tgttataata aatgtacttt taagacctaa gattgattct atatatcctc ctactgttgg
     2461 accaattaat gagccagtag ttgatgcagt tgcaagagta cccaaagccc atcctgaatg
     2521 atttttatct gtctgtgttg caataagagt agtacatgca gtagcataac ccgtaaaaac
     2581 tccttgaagt attcttaatc ctaataactg atagacattt tgaacaaacg ccatggtaaa
     2641 tataactatt cccatcccaa tacttgcacg taaaagcatt gattttcttc catatttatc
     2701 agcagctttc cctcaaattg gcgaaaagat tgctgctact acaaaggtac atccaaaaat
     2761 tatacctgaa tactgttgta ttaaactaac atcagttacc cccaactgtt taatatataa
     2821 tggaagtata ggtgctattt ggctcatccc tatagaacta aaaaacatac ctatccaaca
     2881 tacaaataaa tttcttttcc acaattccat atagaattac accccctgca ttttaaattt
     2941 tttcaataat actaagttta ttaatttatg ctattgttta ctcaatatat ccatcttttc
     3001 ttttataata ttgtttagga aattcataac tcgaaaataa tagtggtgat aaagaatagg
     3061 agtaacttcc agcattacta attgaaatca aatctcctat gtttgctttt ttcaatttaa
     3121 tattatttgc aattacatct aatgatgtac agagattccc aacaacattt acatactctt
     3181 cttcttttaa attatttaat actgaaagag aaaaggcatg atttgatgta tataatggct
     3241 cttgaccttc taattctact ccacaagtaa tattttcaat taaattagaa ataataggtc
     3301 tcataaatcc attaagtcca ttttttacaa taagatattt tttccctctt gatactttaa
     3361 tatctacaat tttaacataa taattacctg atttacaaac tatgaaacgt cctgattcaa
     3421 taagaagtct tgattttagt gtgtttgaat tagtaaaagc aatcttttga gttaattttg
     3481 aaagctcttt aagattaagt ggattttctc taagattatc ataagctact ccaagtccac
     3541 taccaaaatt tataaattca atattaatat acttactttt atttaaattt aaagctataa
     3601 aaaaacattt ttcataataa tgtcctaact tttcaaaatc caatacctga gatttaatat
     3661 gtatatgaat accaactaca gatacataat cacacatact taacatctta aaaacactgc
     3721 tcatatcttc tatatctata ccaaatttgc ttgatttagc actatcatca tccatagtaa
     3781 aatcaggatt tattcttatt cctattttaa ctttctgatt atgcttttta gatatcttat
     3841 ttataagttc tatttctgta atactatctg caataattat gcatttatct aaaacagttt
     3901 ctatatcaat ctctgttttg cctggtgatg aataataaat atcatcttta gaaactccac
     3961 attttgatga aatcataact tcattagttg aagaagcatc tgctccaaaa ccttgctctg
     4021 caatgctttt tacaattttg ttatatggat ttgtttttat agaatataaa aaatcaaaac
     4081 ctaaaatatt atttttcaat tccttacatt tttc
//
LOCUS       DAEOTL010000170         4108 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEOTL010000170 DAEOTL010000000
VERSION     DAEOTL010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4108
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.172"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            524..1438
                     /gene="queG"
                     /locus_tag="KRH82_003845"
     CDS             524..1438
                     /gene="queG"
                     /locus_tag="KRH82_003845"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBG8657093.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRNIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYIFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            1544..3781
                     /locus_tag="KRH82_003846"
     CDS             1544..3781
                     /locus_tag="KRH82_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8657094.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            3978..>4108
                     /locus_tag="KRH82_003847"
     CDS             3978..>4108
                     /locus_tag="KRH82_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBG8657095.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDK"
BASE COUNT         1803 a          316 c          775 g         1214 t
ORIGIN      
        1 gagttagtag ataaaaaaat taaatagata aaaagattaa gtatctaaaa gcgttggtag
       61 ataaaaaaat taaataaata aaaaagatta agtattcaaa agagttagta ggtaaaataa
      121 ttaaatagat aaaaagacta attatttaaa ggagttaagt agatagaaaa gttaaataag
      181 taaatgaaaa agacgaagta tttaaaagag ttagtaaata aaaaagatga agtatctaaa
      241 agagttagta ggtaaaaaac taaataggta aaaagatgaa gtatctaaaa gagttagtag
      301 gtaaaaaatt aaataggtaa aaagacgaag tacctaaaag agttagtagg taaaaaaatt
      361 aaatagataa aaagacgaag tatctaaaag agttaagcag gtaagaaaat tgaatagcta
      421 aaaagattaa gtatttaaaa gagttaatag ctagaaaagg ttaaaaagac taaaaaaaat
      481 aaataaattt aaaaagtcaa ttagattaaa aaggaataat tttatggata ataaggaatt
      541 aaaagcattt tgtaatttaa taggattaaa ctgtgtggga gtagcagggg tagataagta
      601 tgataattta gaaaagatac ttaaggacag acaacaaaaa ggttatttaa ctggtatgga
      661 agaaccaata attgagaaca gaattaaccc aagaaatata atgaaggatg ctaactctat
      721 aatagtctgt gcatttccat atcatataaa tagacaagaa aagaataaaa attcaaattt
      781 atcaaaatat tgtcatggaa aggattatca cattgtagta aaggactttt tacaacaaat
      841 ttgtgattat atttctaaaa cagtaacaga ttttaaatac aagttatttg ctgataatgg
      901 accattagtt gacaggtatt tagcttattt atcaggaata ggatattttg gaataaataa
      961 taatatcata actgatgaat atggttctta catatttata gggtatatag taaataatta
     1021 taaatttgaa gaagataaac cactagaaaa aagttgtttt aaatgtggta agtgtgtaaa
     1081 atattgtccg ggaaatgcta tattgggaaa ttatgatatg aaccccaaaa aatgtttatc
     1141 atatataact caaaaaaaag gagatttgtc agagaaagaa aaagttgttt taaagaatgg
     1201 caaaaaggta tttggatgcg atatttgtca agaagtatgt ccacataatg ttgaaatacc
     1261 aacaactcat attttggaat ttaaagaaaa tataatagat tatttggatt atgatgagat
     1321 acaaaatatt tcaaataaag aatttaaaag gagatatgga gatagagctt ttagctggag
     1381 agggagaaat ataataaaga gaaatatgga aataatttta gataagtatg atgactaata
     1441 ataagagtct gtttcatata ctttaatgtg tatttacttt aacacttgtt gtataaaagt
     1501 catattatat cattaaagtt aaatatgggg aggtggggga atattgaaat ataataatac
     1561 atctgaaata aatccactag attatatatt gggtcaagaa agagctgtag aagctatgga
     1621 attagggttg aaaataaata atccagcgta caacatatat atagctggtg aacctggaac
     1681 tggtaaaagt acttatgcct taaaggtttt aaatgagtat gcatccaaaa aaaatacgca
     1741 taaagattgg tgttatatat ataattttga aaaccctaga gagcctatta tagttgaatt
     1801 agaaaagggg tttggaagag aacttaagaa agatatggag aaattaattg aaagtctttt
     1861 agaagatttt aaaaatgcgt ttgaaagtga aaattttgaa atagaaaaaa ataaacttct
     1921 ggatgaatat gaaatagaaa aagatatgct tttgaagcaa attaaaaaat atggagaaga
     1981 aaaaggattt aaattaaaac agagtaaaat gggaatagtt tttatccctt tgaaagaaga
     2041 ggaagatgaa agtgatgagt ctgatgaaga gttttacaaa gctaaaagag aactagaaaa
     2101 tatggcgata caggtcgtat ataaaattag aaacttagaa gaaatagctg aaaaagcagt
     2161 gttagagctt gaagaagaga tagctaaact tgtagtagaa cctcatatca agagattgtg
     2221 tgaaaaatat gaaaattatg ataagattca aacttatctg gaaaatataa agaaagatat
     2281 aatagaatat atgtatttat tctatttaga tgaagaggag ttaaaagata agtatgataa
     2341 agagcatttt attaaatata aaattaacct atttgtagac aatggaagct caaagaataa
     2401 agaatcagca cctgttgtag tagagataaa cccaagtcca gcaaatctat ttggaaaggc
     2461 agagtatgat tatgcaaatg gaaatataaa gactgatttc acaaaactat tatcaggagc
     2521 atttcatagg gctaatggtg gttatttagt actttatgca gaccaattac taaaatatac
     2581 aatgtcttgg gaaattctta aaaagacttt gcagactaaa aaagtaatat tggaaacaca
     2641 aacagcaatt aaaccagaaa atatgccatt ggatgttaaa ttagtactga ttggaagcca
     2701 ctatatatat gatattttat atagatatga tgaagatttt gaaaaatatt ttaaagtatt
     2761 tgtagacttt gatagtgaaa tggataaaaa tgaagataat gaagaaggaa tagcaagatt
     2821 tatagcatac caatgtgata agaataattt aaggcatttt actaaatcag cagttgaaga
     2881 ggttattaaa tttagcacta gattatctgg tgatttagaa aaactatcaa ctaagtttaa
     2941 taaaataatg gaagttgtaa tagaaggaag tgcttatgca gagtttagaa attcggagta
     3001 tacagagcag tgtgatgtta aaaaagcaat aagtgaaaag agaaaaagaa tcaatagagt
     3061 ggaaacacat atggatgaat caattgaaaa tggatttact ctaatagaaa cagagggaag
     3121 aaaagtagga gtgataaatg gtttgtcagt cttaagtaca ggagaatact cttttggtag
     3181 agcttcaagg attacagcga ccactagccc aggaagtaaa ggcatagtaa atatagaaag
     3241 agaagtaaat atgagtggct ctatacataa caaaggagta cttatattag gtggctatct
     3301 ttctgagaat tttgcacagg atttactatt gtcactaaat gcatatgttt gttttgaaca
     3361 aaattatggt ggaatagatg gagatagtgc atcttctgca gaattatatg tactattatc
     3421 atctcttagt ggagtatcaa ttaaacaaaa tattgctgtt acaggttcta taaatcaaaa
     3481 gggtgatata caagtagttg gtggtataag tgaaaagata gaaggatttt attctatatg
     3541 taaaactaaa gggttaaatg gtgagcaagg cgtcataatt cctagaaaaa atcaaagaaa
     3601 tctcgtttta tcagatgaag ttaatgatgc agtgcgagat ggaaaattta agatatatac
     3661 tgttgaaaga gtagaagagg ctatagagat attgacagat gttaaatttg aagaaataaa
     3721 gaaattggta aaagaaaaat taatatcttt cagcaagata caaactgtgt caaaagaata
     3781 agtttattat agaatttaat gggtatttat gtataataaa aagcaagaac tttaataggt
     3841 ttttgctttt tttgtaaata tatataaatt aaattcttat tttgtatgtt ttatatattg
     3901 atgtttattt ttttgttgat atgattaaac catttataaa taggttttat aaattagtat
     3961 tttaaagggg gataattatg aaaaatgtaa atctaaaaga gataaatgaa aaagatgtaa
     4021 ttttggaaga agagataaat aaaaaaggaa tggataagaa aaatataatt gagaaggaag
     4081 agataaataa aaaaggaata gataagaa
//
LOCUS       DAEOTL010000171         3952 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEOTL010000171 DAEOTL010000000
VERSION     DAEOTL010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.174"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(139..357)
                     /locus_tag="KRH82_003848"
     CDS             complement(139..357)
                     /locus_tag="KRH82_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657096.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(358..765)
                     /locus_tag="KRH82_003849"
     CDS             complement(358..765)
                     /locus_tag="KRH82_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657097.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(851..1339)
                     /locus_tag="KRH82_003850"
     CDS             complement(851..1339)
                     /locus_tag="KRH82_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBG8657098.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(1544..2653)
                     /locus_tag="KRH82_003851"
     CDS             complement(1544..2653)
                     /locus_tag="KRH82_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBG8657099.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIAKGKREEKF
                     NIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(3027..3197)
                     /locus_tag="KRH82_003852"
     CDS             complement(3027..3197)
                     /locus_tag="KRH82_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657100.1"
                     /translation="MDSNNNTIKSTVKKGISFDSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(3369..3758)
                     /locus_tag="KRH82_003853"
     CDS             complement(3369..3758)
                     /locus_tag="KRH82_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8657101.1"
                     /translation="MLADPCEEMIDKYLNKGTMYALYDNKELTCIAVVNEISKEICEL
                     KNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSESGVPFYEKFGFVYSHKIKN
                     FFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1349 a          651 c          355 g         1597 t
ORIGIN      
        1 ctttttcatc tataaatcat tcattcttta atccattagc ttggtttttc atctataagt
       61 catttattct ctaatctatt agcttggttt tttacctata attaattcat tctctaatgc
      121 ataagtaata catgaaattt aaatattatt ttcttcaata aattcaaaca actcttctac
      181 agttgtatca aataccttag caatatccat tgccagtttt aaagaaggat tgtagcgacc
      241 attttctaaa tgtacaatag tttcacgtct tactcctact gactttgcaa gttcaccttg
      301 tgtcataagg ttcttttctc tataggattt aatttttgtc tttagtaata ctgacaccta
      361 attgtatatc ccctttctgt caaaatatat aaatagaatt aacttcaaca aggattgaat
      421 aaacaaaatg actaataaag acattcctat atttaaattt gacacattta tgtccaaagt
      481 tacaagaaat atagatacta tagctacaga aaaaaacaat acttttattg caatatcatt
      541 aactcttgat agtatacatt ttgatgcctc atcaattaaa tcatcatact ttttattata
      601 gacccactga gctcccatag ctaataccca aataattata ggaagatatt caatactact
      661 tcctttaaaa aaatacttat ttactaatgt agctccaata caataagaaa ttcccaatat
      721 ttctgaaata agtgttgatt taataccagt ttgttgttta gacatataaa atccccctta
      781 aaaagttatg tatttataac acctcttgtt ataaatatat aacttttttg aataaatttc
      841 aataaaaata ttattttgca acaaattctt ttattaattt tacattagat agaggcactt
      901 tagatgtcac tccttgcaat gtcaaatctt ctatattaac ttcatttaat tttgaacaca
      961 gttctaagtc aaatattctt tcccaactta ccttcttttc aatttgttca tcttcataaa
     1021 gctctacagc aatatccatt aaaggtaaat gccataaatc aaattctgat aataacacat
     1081 tgtcttcact tatttctatt tcaagtaaaa cacctttttt tcctttttct aaataaccac
     1141 tacatcttaa atcaggtctc ttcgtccaaa cccatatcat actatcatca aattcatata
     1201 ttctatttgt catttgacta tacatccatt tgtatggaat atcaaagtct tctaatataa
     1261 aagaataatc atttgataga tatttattgt ttttattgtt attccaaaat tctaaagtct
     1321 gtatagtata aaatttcata tataaatcaa cccctttgtt tttctataag aaggagatgg
     1381 ttcaaacttt tattttgaat tatctccttt atttatacac ctctttgtac ctattattta
     1441 tatatctctt tatatctacc atatttaaat aacaaagttt tatattaatt taaatttaaa
     1501 agaggaagct ttgtatttat ctagtgccat ctcaatcata gtattagttt tgattataga
     1561 ctttttcaac ctctgattta ttcaaatcat ctataatatc gcatatttca ctcaaattgt
     1621 atcctttatt ttttaatttt atgatgatat taaatttctc ttctcttttc ccttttgcaa
     1681 tacctttttc gatacctttt tcaatacctt cttgaaaaat ttcttcttta aaatttctac
     1741 ttttattcat aatatacgca cctctcttta aatttaataa atagtcctca ttactaccta
     1801 attcttttaa tctatcaagt gctcttttaa taacataatc cgttttagat agtattctaa
     1861 tatctatatg agaaggatta tcaataagtt taccccatat tagaactctg tttgctatac
     1921 aactggattt acgaattttt ggaagttcta taaaatataa tgcagtttta ctagaaaaaa
     1981 tatctggatg cccgtccatt gttaatctca ggcaatttac ataatcttct atgtgattat
     2041 attttacatg atttagtata tgtattccaa cagtttttcc aatttcttta tattctttac
     2101 cttcttctaa ctttctacca tgtacacgac taagataata ttcagctctt tccaaataat
     2161 cctcttcaag agctctttgc atctcaatat ttatatggtt acgttcttca tcttcagcca
     2221 aaatatcaag tctaggtctt ttctcaccaa tgtaattaat tgttgggtcg gtttcaacct
     2281 taattattct ttttatttga gtgaactgtt tgatattcct attagcatat ggagcatctt
     2341 tgaggatatc atttataaaa tttgcaagta aatcgtaatc attatttaaa gtaaacaatg
     2401 atttaaatac ctcatcatac tcaggcttag catacccatc ttcagttaca acttctccaa
     2461 cattttcact agtcaatatt tcttttggaa ttaaatcctt gattttatct aatttttcat
     2521 tagaaaaatc acctctacta agtatgtcat ttaatttttt ggtccattct ctgtcctttt
     2581 cttcaattat agttcgttta tactcttttg atgttttaat aatcttagat ttttcttcta
     2641 atttttcttt catatcaaca cctctttttt attattaccc atttcttcat cccaaagtct
     2701 gaacttctaa gtaaaatttg cattattgaa ataagaacct tataaactta tatatcatta
     2761 ctaaagttaa gactttaaag agaagcactt agattacaat agattttaga tagctttctt
     2821 tttaaaactc ttgttgataa atgaatgaat ataagagtat gtattaaaat agagatactc
     2881 atctttttca ttgtttaagt aatgaaaata tattttattt aatacaaaaa agagtgcctt
     2941 ataaactaaa aagttcactt cgagacactc acttacgttt tgtttcttaa acttcacaat
     3001 attacatact tatttattaa tttaatctat gcatacttaa cccaataata aagtacatat
     3061 atccaactca ttaagccatg aaaaatagcc catggaatag atttccatgc agtataagaa
     3121 ataatcattg ctaaacaaga atcaaaagaa ataccctttt taacagttga ttttatagta
     3181 ttattatttg aatccataat taatcctcca aaattcaaaa taaacaagtt attatatatc
     3241 ttatttgaat ctaatacaat ataacagctt ctaaataaat tatactctta ttatacataa
     3301 tttataaatt ataattccga taattatatg aataaattat gtatattaac ctaaaaatat
     3361 tatcctatct aaaagttata tgatagatac aacatgtcaa cacattgtaa ttctccttca
     3421 aagattggtt ctggataatt atctacaaaa aagtttttaa ttttatgtga ataaacaaat
     3481 ccaaacttct cataaaaagg aactccgctt tcagatgtac caacaaccat tgatgaatat
     3541 tttttactat aaacatctaa aagatgataa atcatctttg aggcataacc catattttga
     3601 aaatgctcat atgtagcaat gttttttaat tcacatattt ctttggaaat ttcatttaca
     3661 actgctatac aagtaagttc tttattatca tacaatgcgt acatagttcc tttattgaga
     3721 tatttatcaa tcatttcttc acatgggtcg gctaacatta aaaggtcaat ttgacttttt
     3781 tatttatttc tatagttttt atttctatca taagttctcc accctcactt tattcaaacc
     3841 ttaatttagc aaacttctta cagtacttat ttagttcatt ttgatatata tttttacttt
     3901 ttaaaatata gtgataattc cctagaatat taatactaat aataaattat aa
//
LOCUS       DAEOTL010000172         3937 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEOTL010000172 DAEOTL010000000
VERSION     DAEOTL010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.175"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..282
                     /locus_tag="KRH82_003854"
     CDS             <1..282
                     /locus_tag="KRH82_003854"
                     /inference="COORDINATES: protein motif:HMM:NF014225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657102.1"
                     /translation="NSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGND
                     STRDGFKIRRTAIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            540..1589
                     /gene="carA"
                     /locus_tag="KRH82_003855"
     CDS             540..1589
                     /gene="carA"
                     /locus_tag="KRH82_003855"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBG8657103.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            1782..>3937
                     /gene="carB"
                     /locus_tag="KRH82_003856"
     CDS             1782..>3937
                     /gene="carB"
                     /locus_tag="KRH82_003856"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) large subunit"
                     /protein_id="HBG8657104.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQG"
BASE COUNT         1630 a          400 c          778 g         1129 t
ORIGIN      
        1 aatagcttaa gagaaaatgg aatagaggct gatatagtaa atagagtaga agaatctaga
       61 ccaaacatat tagatgctat aagaaataaa caagttgata tagtaataaa tacaccaact
      121 aaaggaaatg actctacaag agatggattt aagataagaa gaacagctat tgaattttct
      181 actgaaataa tgacatcttt ggatacacta aaagctttag tagaagttaa gaagaaacat
      241 ttaaataaag atgagttaaa agtttacaat atagctgaat agaaattaag ttgattgtat
      301 agtttaagaa tttaattatt aaataaaaaa aaagaggtta ttttttctag gagtttttac
      361 ttttgagata acttcttttt tttaagaaat ttgtagtata atagaaaaag ataaaaaata
      421 aatgtaaata agtataaaac tagaatgtaa aagtgaaaaa tagatataga tatttaaaag
      481 cttatattta gttaatgttc tttagtttgt ctaaagagaa ttataggagg tactgtagta
      541 tgaaagcaag gttaatatta gaagatggaa cagtttttat aggaaaggca tttggatatt
      601 tagaagaaag tgtaggagaa gtagtattta atacttcgat gataggatat ggtgaagttt
      661 taacagaccc ttcttactat ggtcaaatag ttactatgac ttatcctctt gtaggaaatt
      721 atggtataaa tttatcatca gcagagtctg aaaaagttca agtaaaggga ttcatagtaa
      781 gggagaaaag tgattctcca agtaatttta gatgtgaaat tgatatagac caatatttaa
      841 agcaaaataa agttatcgga cttgaaggaa tagatacaag agctttgact aagatactta
      901 gaaataatgg aacaatgaaa ggtataatta cattagaaga cagtaaatta gaagatgtta
      961 aacataaatt ggataagttt tcaaatacag aagcagttag aactgttaca agaaaagaag
     1021 tagagcatat aaaaggaaat ggtccaaaag tggctgttat ggattttgga gtaaaaagaa
     1081 atatattaag atcatttata gctcgtggat gtgatataac aatatttcca gctacaacat
     1141 ctccagaaga tgtattgagt ataaaccctg acttaatatt cttgtcaaat ggacctggag
     1201 acccagaaga cttagaagat gttatagaaa atataaaagc tcttattggt aaaaaaccta
     1261 tagttggaat atgcttagga catcaacttt tagctttagc tcttggagga aaaactgcta
     1321 aacttaaatt tgggcataga ggtggaaatc atccagttaa agacttagaa gaaggaaaag
     1381 tatttataac ttctcaaaat catggttatt atgtttcaga agttcctgaa caaatgaaag
     1441 tgacacatat aaatttaaat gataatactg ttgaaggaat gagacatgag aagctagatg
     1501 tatacagtgt tcaataccat cctgaagctt gcccaggacc aaaagataat gactatattt
     1561 ttgataaatt tttagaatta gtaaaataaa caacattaga atagctaact aaaaaacaag
     1621 aataacttaa atcaaaaagt ctggtttaat taacatagat gtattaaata gatgtattga
     1681 tgagtaaatt tgaacttaag ataaaataaa gtaattaaag ttgattgtat agatgatgaa
     1741 gataagaact gtgaaaattg tttagataag gagaaagagt tatgcctaaa ttagatagta
     1801 taaagaaaac tttagtatta gggtcagggc caataataat aggtcaagct gcagagtttg
     1861 actattcagg aacacaggcc tgccaagcat taaaagaaga gggaattgaa gttgtattag
     1921 taaatagtaa cccagctact ataatgactg ataaagaaat tgcagataaa atatatatag
     1981 aaccattaac aatagaattt atagaaaaaa taatagaaaa agaaaaacca gatagtttac
     2041 ttgcaggtat gggtggtcag acaggattaa acttagctgt agaattacat gatgctggta
     2101 tattagataa atataatgta aaagttatag gaacatctat agaatctata aaaaagggcg
     2161 aagatagaga tttatttaga gaagtaatga aagaaataaa tcaaccagta atagttagtg
     2221 atatagttac aaatttagaa gcaggtcttg agtttgccaa taagatagga tatccagtag
     2281 ttgtaagacc agcatatacg ctaggtggaa ctggtggagg tatagctgat actgaggaag
     2341 aattaagaga aatactttca catggactac agctaagtcc tgttggacaa gttcttcttg
     2401 aaaagagtat aaaaggttgg aaagaaatag aatatgaagt aatgagagat ggaaatggaa
     2461 actgtataac tgtatgtaat atggaaaatg tagacccagt tggagttcat acgggagaca
     2521 gtatagttgt tgctccaagt caaactctaa gtgatgaaga gtatcaacta cttagaaagg
     2581 catcaataga cataataaat gcaatagagg ttcaaggtgg atgtaacgtt caaatagctt
     2641 taaacccaca tagtttagaa tatgcgataa tagaaataaa cccaagagtt agtaggtcat
     2701 cagccctagc atcaaaagct acaggatacc caatagcaaa agtagcagct aagatagctt
     2761 taggttatac tttggatgag atagaaaatg cagtaactaa aaaaacttat gcttgttttg
     2821 agccaacatt agattatgtg gtagtaaaaa taccaaagtg gccatttgat aaatttagac
     2881 atgccaatag aaaattagga actaagatga tggcaactgg tgaaatcatg agtataggaa
     2941 gtaactttga ggctgctatt cttaaaggta taagatcact tgaaacagga aaatattcat
     3001 tggttcatgc tccatcagaa ggtagaacat tagaagaatt aaaggctaga gtagtagtac
     3061 ctgatgatga gagactattt gacttagctg aaatgataag aagaggctat aaagtagaaa
     3121 tgatatcaga aataactggt gttgataagt ggtttataaa taaatttaaa tggatagtag
     3181 aacaagaaga aaaattaaaa gttctaaaaa tagaagactt agataaagaa tatttacatg
     3241 aattaaagaa aaagggattt tctgataaag gtatatctga cttaatgaag ataagcccag
     3301 aaaaattata tgaattgaga agtttatata atatacaacc agtttataaa atggttgata
     3361 catgtggagg agaatttgaa gctctatcac cttattacta ttcaacttat gaacaatatg
     3421 atgaggtagt agttagtgat aagagaaaag ttgtagtatt gggttctggt ccaataagaa
     3481 tcggtcaagg aatagaattt gactattgtt cagttcattg tgtaaaatct ttaagaaaaa
     3541 tgggaataga aactataatt gtaaacaata accctgaaac tgtaagtacg gattttgata
     3601 catctgataa gttgtatttt gaaccattaa cagaagaaga agttttaaat ataatagaaa
     3661 aagaaaaacc agaaggtgta atactacagt ttggtggaca aacagctata aaattggcta
     3721 agtttttaca tgaaaaaaat atacctatac tgggaacaga ctttagagat atagatgcag
     3781 cagaagatag agaaaaattt gatgatttac tagagagact agatataaat agaccaaaag
     3841 gaaaaggtgt atggacaact aatgaaggtg ttgaaattgc taaggagtta ggttatccag
     3901 tattagttag accatcttat gtacttggtg gtcaagg
//
LOCUS       DAEOTL010000173         3574 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEOTL010000173 DAEOTL010000000
VERSION     DAEOTL010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.176"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..2201
                     /locus_tag="KRH82_003857"
     CDS             <1..2201
                     /locus_tag="KRH82_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBG8657105.1"
                     /translation="EAGKTATLNVSDTPKVTDTLIELFKIDMETKKDNPQGNASLAGA
                     EFTWKYYAGFYNKDNLPAEATRTWVTKTIAETDSYGTTHYITKLADAYKVSGDSFYMQ
                     DGKAVLPLGTLTIEETKAPNGYLLEGAYMQAGDKSEQIKGLYVTQITEDDDLAVLSGS
                     NQFSVSDKVIRGGVKIQKRDLETGDMKPQGSATLKDTAFDIISLNDNSVLVEGKLYKK
                     NEVVKTIRTDIEGVASTSADLLPYGKFRIVESEAPDGYLTDGAKPIDFTITENGKIVD
                     LTDKAHSIYNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHIVVTDNNGQFST
                     SADWASHKHNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYVIEELRSESNKGFELIPP
                     FEIVVSRNNLLIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEITIVDTVKLDGLT
                     KGTKYQLKGWQMLKEENAELIIDGKRAENDYTFVADEEEMKVEIAYTFNASALGGKNL
                     VTFEELYDLSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATNKDGNKELEAGKN
                     VTIIDTVTLEGLEVGTQYKLVGWQMLKEENAELLINGKCVENDYTFTADSETMKVEVA
                     FTFDATSLDGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPET
                     PQIPEKPSRPSDSPKTGDSTNVMAFLVMLLASAGGLAGTYLYKRRKMKKS"
     gene            2434..2760
                     /locus_tag="KRH82_003858"
     CDS             2434..2760
                     /locus_tag="KRH82_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8657106.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            2776..3159
                     /locus_tag="KRH82_003859"
     CDS             2776..3159
                     /locus_tag="KRH82_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8657107.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFMQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTFGGADVDWYVKAED
                     IVLKNKGNQNAGNPQNHVPQGQTKK"
     gene            3327..>3574
                     /locus_tag="KRH82_003860"
     CDS             3327..>3574
                     /locus_tag="KRH82_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657108.1"
                     /translation="MEIGKKLKNARVQSGMTQENVAEKINVSRQTISNWENEKSYPDI
                     INVIELSNLYSISLDELLKGDEKMIEHLEESTNVVKSN"
BASE COUNT         1238 a          642 c          837 g          857 t
ORIGIN      
        1 ttgaagctgg aaagacggcg actttgaacg tatctgatac gccaaaagta acggacactt
       61 tgattgagct tttcaagata gatatggaaa caaagaaaga caatccgcaa gggaacgctt
      121 ctttagcagg tgcggaattt acatggaagt attatgctgg cttctataac aaagacaatc
      181 tccctgccga agctactcga acatgggtta caaagacaat cgctgaaaca gacagctacg
      241 ggacaactca ttacatcaca aaattagcgg acgcatacaa ggtgtctggc gacagcttct
      301 atatgcaaga cggaaaagcc gttcttccac ttgggacact aaccatagaa gaaacaaaag
      361 ctccaaacgg ctacttgtta gagggtgcat atatgcaggc tggcgataag tccgaacaga
      421 taaagggctt atatgtaaca cagattaccg aggacgacga ccttgccgta ttatctggaa
      481 gtaaccagtt ttccgtatca gacaaggtta tccgtggcgg tgtgaaaatt cagaagcgag
      541 atttagaaac gggcgatatg aagccacaag gaagtgcaac cttgaaagat actgcttttg
      601 acatcatttc cttaaatgat aattctgttt tggttgaggg caagctatac aagaaaaatg
      661 aagtggtaaa gacaattcgt accgatattg agggtgtcgc ttctacttct gctgacctct
      721 taccttatgg aaaattccgt attgttgaga gtgaagctcc cgacggttac ttaactgacg
      781 gtgcaaagcc gattgatttt acaatcacag aaaatggaaa aatcgtggac ttaaccgaca
      841 aagcccattc tatctataat cagattaagc gtggagatat tgagggtgta aaaatcggtg
      901 caggcacaca caagcgtctt gctgatgttc cctttaggat cacaagcaag acgacaggag
      961 aaagtcatat cgtggtaact gacaataacg ggcagttctc cacttctgct gactgggctt
     1021 ctcataagca caataccaac gcaggcaaga ccagcgagga cggtgtgtgg tttggaactt
     1081 ctgaaccaga cgacagcaaa ggtgcgttac cttacgatac ttacgtcatt gaggaattac
     1141 gctctgaaag caacaaaggc tttgaactta tcccaccttt tgaaatcgtg gtatcaagaa
     1201 ataatctttt gattgattta ggaacgctga ctgatgaata cgaaaaagaa atctctatcc
     1261 ataccacagc gaccagcaag gacggcgaaa agactatcct tgcaggaaaa gagattacga
     1321 ttgttgatac tgtcaaatta gacggactta caaaaggcac aaaatatcag ctcaaaggct
     1381 ggcagatgtt aaaagaggaa aacgccgagc ttatcattga cgggaaacgt gcagaaaatg
     1441 attatacctt tgtcgctgat gaggaagaaa tgaaagtgga aattgcctat acattcaatg
     1501 cgtctgcttt aggtggcaag aaccttgtta cctttgaaga attgtatgat ttgagcaatc
     1561 cagacgaacc cgtgaaagtt gcggaacaca aagacattga ggacgacggg cagaccgttt
     1621 taatcacaga gcgtatcatc aaaattcata cgactgctac gaataaggac ggcaacaaag
     1681 agcttgaagc tggaaaaaac gttacaatca ttgataccgt aaccttagag ggcttagaag
     1741 ttggtacaca gtacaaactt gtgggctggc agatgttgaa agaagaaaat gcagaacttc
     1801 ttatcaatgg aaaatgtgtg gaaaatgatt atacgtttac tgctgacagc gaaactatga
     1861 aagtggaagt tgcttttacg tttgacgcta cttctcttga cggtaaacag cttgtaactt
     1921 ttgaagaatt gtacgattta agcaatccag acgagccgaa gaaagttacc gagcataagg
     1981 atattgagga taagggacag acgattacct ttaaggaaaa gccagaagaa ccagagaaac
     2041 ccgaaacacc acagatacca gaaaagccga gcagaccgag cgacagtccc aaaacgggcg
     2101 acagtacaaa tgtaatggca tttcttgtga tgttgcttgc gtctgctggt ggactggctg
     2161 gaacatatct ttacaaacgc cgtaaaatga agaaatcata aggcggtaac ggtatgatga
     2221 aagaaaaatc acgctctccg ccgaagctgt caaacggcag acttttgctt attctggctt
     2281 gtctgccacc aacctgcaag aacacggata gtcaagggtg cgaagcattg attttaccct
     2341 ttactatctg ggggattgct ggtacttccc aaaccgccag aataagaaat tacaatcaat
     2401 ttatcaaaat agaaagaaac gaggtaaaac attatggaaa tgaaatatgt cgtgccagat
     2461 atggcacagt cttttggaac tcttgaattt gcaggcgaaa gcgagcctat ctttgaaaga
     2521 gataaaaata accgtagggt cttagccaga cgaagctata acctttattc tgacgtacag
     2581 aaaggcgaaa atgttgtagt ggaaattccc gtgcaggctg gcgaaaagaa gttcaagtat
     2641 gaacagaaag taaaacttgt caatccgaag ttgtacggca gaggttacgc aatcggggat
     2701 atgggacata ccgattatgt attagttgct gatgatattg tagcagttga agaaaagtaa
     2761 aggagtgaag aatttatgag attatcaaac gggtttgtta ttgacaaaga gaaaacattt
     2821 ggcgaattaa aatttacagc ggtgcgtgat gtgtttatgc agaatgagga cgggacaccg
     2881 agtacccagc ttaaaaagcg tatctatgac ttgaaatgta gtctgcatgg tggaattatc
     2941 cccgtgtccg taccgccaga agtgccgtta agggaatttc cgtacaatgc agttgtagag
     3001 cttgtcaatc ccgtagccga tacggtatca agaaagacgt ttggtggtgc agatgtggac
     3061 tggtatgtaa aggcagagga tattgtgttg aagaataaag gcaatcagaa cgcaggcaat
     3121 ccacagaacc atgtaccgca gggacagacg aaaaaataaa tctaggtcat agattatact
     3181 ctgaaattac agtataatga gccaaaagag ccgtatttaa gctatgtaaa ataattttga
     3241 caaggaaaaa aaggatttgt cgaagatatt ggatagacat ttgagggtta atatatgaca
     3301 atgacaccga aaggagcaat cggaatatgg aaataggtaa gaaacttaaa aatgcacgag
     3361 tacagtctgg aatgacacaa gaaaatgttg cagaaaaaat caatgtatca aggcagacaa
     3421 tttcaaactg ggaaaatgaa aaatcttacc cagacattat caatgtaata gagttgagca
     3481 acctatattc tataagtctt gacgaattgc taaagggtga tgaaaaaatg attgaacatt
     3541 tagaagaaag tacaaatgtt gtaaaaagca acca
//
LOCUS       DAEOTL010000174         3558 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEOTL010000174 DAEOTL010000000
VERSION     DAEOTL010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3558
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.177"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            137..475
                     /locus_tag="KRH82_003861"
     CDS             137..475
                     /locus_tag="KRH82_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBG8657109.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAKAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            942..1445
                     /locus_tag="KRH82_003862"
     CDS             942..1445
                     /locus_tag="KRH82_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBG8657110.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            1492..2451
                     /gene="moaA"
                     /locus_tag="KRH82_003863"
     CDS             1492..2451
                     /gene="moaA"
                     /locus_tag="KRH82_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBG8657111.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLLENKCSDTNRRMYEIGG"
     gene            2455..2925
                     /gene="moaC"
                     /locus_tag="KRH82_003864"
     CDS             2455..2925
                     /gene="moaC"
                     /locus_tag="KRH82_003864"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBG8657112.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            2961..3392
                     /locus_tag="KRH82_003865"
     CDS             2961..3392
                     /locus_tag="KRH82_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBG8657113.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         1481 a          307 c          677 g         1093 t
ORIGIN      
        1 catattattt tatagtatag attggttaat aaaagtacag attggttaat gaaacattaa
       61 attacaatat ttgttaaaaa aattgtgagt tacatgatat aatgtattaa ataggatact
      121 aaggagttga tatattatgt taatagtaac tacagaaaaa gtagaaggta aaaagatatc
      181 aaaggtttta ggattagtga gaggaagtac aataagagca aaacatgttg gaaaagatat
      241 aggagcaagt tttaagaatc ttgttggagg agaacttact ggatataatg aaatgctcac
      301 tgaagcaaga caaattgcca taggtagaat ggttgaagat gcaaaagcta aaggtgcaaa
      361 cgcagtaata gcatttagac tgtcttcagc ttcagttatg caaggagcag cagaaatgct
      421 tgcttatgga acagcagttg ttttagaaga tgataatagt attcttgaaa aataaaatat
      481 aaatagttaa aaagaggcat cttttaaaaa ttttatggat gccttttttt atttgaaaaa
      541 actaatttga gaagaaattt taactattat gacaataaaa ttagggtgat attatataaa
      601 taagtaaaat tatattatat aatgtatggt atagacttta aaaattttat ttgtagagaa
      661 aaatatggac aatgttataa taattataga aattaaaagt acttacattc attatgtatg
      721 tgacatgtat aattagtttt atatttaata cagttttgaa gtaatatctt cattttgaga
      781 acgttggaat aataaaaaat gtatgtatta taggtgatat aaataaaaaa taaatataat
      841 atgttatatt gctgatagaa aagagaataa aagaaaatag gttttattaa aagagatttt
      901 tatttatagg acttaatcga tgtatagagg ggtgagaaca tatgtttaat gttgcaatta
      961 taacacttag tgataaagga tatgaaggaa aaagagaaga tataacagga aaaaagttaa
     1021 ctgaatttgt tgaaaataca ggagcttata aagttactga atatgtactt ataaaagatg
     1081 ataaggaaat gctaaaggaa aatattataa gactttgtaa tagtaataaa atagatttaa
     1141 ttcttacaaa tggaggtact ggtttttcaa aaagagatat aaccccagaa gcaactaagg
     1201 aagtgttgga aaaagaaata ccaggtctga gcgaatatat gagaatgaaa tccacagaaa
     1261 ttactaaaaa ggccatacta agtaggggtg tgagtggaat aagaaataat tctataataa
     1321 taaatttacc tggaagtcct aaaggtgcag ttgaaaatct aagttttata attgatgttt
     1381 tagaccatgg catagaagtt ttaagaggag aagctacaga atgtgccact aaaaaaagtg
     1441 aatagtatat aatctagata gataaaaaat agacaaagag gtagataaag tatgattgat
     1501 aagtatggaa gaaaaataga ctaccttcgt atttcactta cagataagtg taatttaagg
     1561 tgtgtctatt gtatgccacc agatgtaaaa tttgataaaa attatataaa tgaaaatcta
     1621 agctttgaag actacaagtt tattataaag gctatggctg aacaaggtat aacaaaaatt
     1681 agatttactg gaggagaacc tcttttatat cctaaattaa atgagcttat aaaatttaca
     1741 aaagaagaat gtggaataaa taacatagga atgaccacta atgctattgg gctttctgat
     1801 agaatctttg agcttgaaaa atgtggctta aataaagtta atataagttt agattctttg
     1861 aaggaatata agtataaatc cgtaacaaga ggaggaaact taaaagatgt cttaaaatcg
     1921 attgaatctt gtttaaactt aggtataaaa gtaaagttaa attgcgttgc tataagtggg
     1981 tttaatgatg atgagcttaa agattttatg tttttaacag ttaaatcacc aattgatgta
     2041 agatttatag agcttatgcc attaggtgag gctaatagag tttataagaa gggttatttt
     2101 aatgtaaaag aaatgattga aaaaatatat ggtttatata aagtcaaaaa tgatgaaaaa
     2161 agtacagcag aatattatat gtttaaagga gctaaaggaa gaataggaat tataactcca
     2221 ttaagctgtt cattttgtaa cacttgtaat cgtattagac ttacttctag tggtgcaata
     2281 aaattatgtc tacattcaaa agaagaaata gatataaaac catttttaca taaaccattg
     2341 ttatttagag aatctatgaa agatataata aaacaaaaac cagaaaaaca tcatttacta
     2401 gaaaataaat gtagtgatac aaataggcgt atgtatgaaa ttggaggata agtaatgtta
     2461 acacatataa atgaaaaagg gtatgccaag atggtggaca taagtgaaaa agatgatact
     2521 aaaagaacgg ccgtagctac agctacaatt actcttagta aggaagcatt agaaaaagta
     2581 aaaaatggtc agataaaaaa aggagacgta ttgtctgtag ctcaagttgc aggtataatg
     2641 ggagctaaaa atacatcttc aaacatacca atgtgccatc agattaaatt agttggatgt
     2701 gatttagaat ttgatgtaga tgattctatg tctgctatta agatatacgc aacctgtaaa
     2761 tctcttggga aaactggagt agaaatggaa gctttaaatg catgttcttt agcagcactt
     2821 acaatttatg atatgtgtaa agcagttgat aaaaaaatgg ttataagtaa tatccatctt
     2881 gtagagaaga ctggtggaaa atcaggagat tttaagttcg agtaaattaa taatatattg
     2941 ggttaaaatt tggaggaaat atggcgaagg tagtgtcaat aaatataagt gagaaaaaag
     3001 gtgtaattaa agttcctgta caatgtgcag agctaaaaat aaatcatggg atagttggag
     3061 atgcacatgc aggaaactgg catcgtcaga taagcttact tggaaaagaa agcatagata
     3121 aaatgaaaat gaaaggcttt gaccaattaa aatatggaga ttttgctgaa aatgtaacta
     3181 cagaagggat agaagttttt tccctgcctg ttggtacaaa gttaagaata gggcaatgtg
     3241 aagttgaagt aactcaaata gggaaaaaat gtcacaatgg atgtgaaatt aagaaattga
     3301 caggtgactg tgtgatgcca cgagaaggaa tttttgtaaa ggttctaaaa gaaggaatta
     3361 taaatgtgaa tgattcaata gatgtaatct aatgaagtga ctattaaaat ataattataa
     3421 gtaaatacta ttaagattta aatatatatt ttaagagaga attaatttta ataaaatatt
     3481 ttagttataa attggaatat tggttatata aagctatgaa tgtaaaatca tagctttttg
     3541 tttttgaatt ttaaaata
//
LOCUS       DAEOTL010000175         3489 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEOTL010000175 DAEOTL010000000
VERSION     DAEOTL010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3489
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.178"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1123)
                     /locus_tag="KRH82_003866"
     CDS             complement(<1..1123)
                     /locus_tag="KRH82_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBG8657114.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNSGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHK"
     gene            complement(1511..3448)
                     /gene="htpG"
                     /locus_tag="KRH82_003867"
     CDS             complement(1511..3448)
                     /gene="htpG"
                     /locus_tag="KRH82_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBG8657115.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKHYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLFIEL"
BASE COUNT         1092 a          626 c          344 g         1427 t
ORIGIN      
        1 acttatggta catttccttt atttgttcct tattaaaata ctttggatgt ctcttaatat
       61 ttgcaactga tattttcata caattatcag ttaaccaatc tatatctgat ttttcaatac
      121 ctaaatcact tagctttata tctaaatcta tttttttaag gaaatttcta attgcatctg
      181 aacaatcttc tgcacaagtt cctcctaata cctttgaaat attaccaaat ctttcaatat
      241 cactatccca tgaactttct ataatagtag gagtcaaagc tgcaagtcct tttccatgca
      301 ttacatctct aagaccactt acaggatgct ccattccatg tggcaaggct gtacccgctg
      361 taccaatcgt cattcctcca atagtacttg caagtgttat cttttcccat gcttctaaat
      421 cattaacatc attatatacc tttattaggt tttctgatat aagttcaatc ccataaatag
      481 cttgtacatc tgcaagaggg tttcttccat tagaaagata tgcttccata ttatgggcaa
      541 gtgcatcaaa tccaactgat gcaattatat gttttggcat tgtaaccata agttctgggt
      601 caattattga tgcttttgca tacatactat tcttctttat agatttttta tctttagttt
      661 ctgaatttgt aagtactgca aaacaatttc cttcactacc tgtacctgat gttgttggaa
      721 ctaagattat aggtaaagct tcttcacctt gtctaattcc aaatatataa tcatttaaat
      781 ctcctgaatt tttataagaa aaagctatac tcttggcagc atccataata cttccaccac
      841 caagccctaa aacacaatca catccagttg attttataat ttctactcct gaatatatag
      901 tagttataag aggattttgt tctactctat caaaaacttc atattctatt ttagagtctt
      961 ttagtaaatc tattgtttta tcaagtaatc cagttttctt tgtactattt ttacctgtta
     1021 ctatcaatac ttttttgcca tatttagata cttcttttcc cacatcatta attctgcctc
     1081 tcccaaataa gatatttact ggcaaattat aattaaaatt catgctaaaa cctcctattt
     1141 ctactttagt aataatttta tgtttttaac aaagtgtaat tatgtattta aacataaact
     1201 aaaaaacaat cttttactta attatatgta ttatcttatt atatatcaag ttaactatat
     1261 ttaactaaat agagtttttt attagaacct acttaaatat ttaaaaatta accaaagata
     1321 aaaaaataaa gaatggtctg tctcaaaata gagataaata tatttttcat tgttgaaatg
     1381 attaaaataa atttaatttc acataaaaaa agcgccccat gaactgaaaa gttcattttg
     1441 agacacttct ttatcatcac tgatattgaa tactttttat aaatttgctt caatgtattc
     1501 aaattcaatc ttataattct atgaaaagac tcataagctt attacttctt tgtacaaatg
     1561 aatctaactc atctggcttt aattctttat tagaaagtaa agctaaatct gctatctggt
     1621 tacaaataag cgtaatctta tctttctttt cctcatcatc tttaagagaa accaattttt
     1681 tgattattgg actgttctca tttattacaa gagttttttc ttcctcaaaa ttcattccta
     1741 aatccattcc agcaaatctt gactgcattt ctgccattct aatagattgt tctgatacta
     1801 acaccatagc tggagtgtct tcatttttca atccttctac agaataatgc ttcactcttt
     1861 ctccaacagc ttctttaaac agaccttcta tcttagctat ctcttctttg ttttcttcac
     1921 tatctttatt ttcattttta tcttttaata catcagaaag gtctgcatct attctattaa
     1981 acttaactcc attctcttta tattccataa atgaaataaa atgagtatct attgatgagt
     2041 ttaaaacaac agcacttaag tcgtattctt taaatagttt aatgtattga gattgctgtt
     2101 ccttatcact tacataaaat accttatttt catgtttgtc cttacatttt tctaaataat
     2161 cttgtaatgt tatatactca tcatcaatag ttttgaataa tatacattct tttaccttct
     2221 catagaaact ttcatctttt aagcaaccat atttaataaa tatttgtata tcatcccaaa
     2281 acttattgta ttcttctctt tcatttttac aaagagattt taacttatca gctacttttt
     2341 taattatatg cttagaaatt ttgcttacgt ctctgtcatt ttgtaagaaa cttcttgata
     2401 catttaatgg taagtctggg cagtctataa caccttttaa taaaagtaaa aattctggta
     2461 taacttcttt tatattgtca gctacaaaca cttgattgtt gtataatttt acttttcctt
     2521 cagtcagttc aaactcattt tttaatttag ggaagtaaag tatacccttt aaattgaaag
     2581 gataatctac atttaaatgt atccaaaata aaggttcatc aaatacattg aatacctttc
     2641 tataaaactc tttatactcc tcatcagtac agtcttttgg agattttaac catagaggat
     2701 tagtgtcgtt taaaggctca attacttttg catctacaat ctcttctttt ccatcttcct
     2761 tttgtttttt agctttttct tctgcttctt tagcttctct ttctaatctt tcaacatctt
     2821 ctaaatatat ttctactggt aagaaagaac agtatttatt tattattcct cttacagtaa
     2881 attcatctaa aaattcttta ctatcatcat caataaatag tgttatagta gttcctctat
     2941 catttctagt atctgattca gatatttcgt attctgtacc accttcagat atccatctta
     3001 caggagttgc accttctgta tatgaaaggg tatctatttg taccttttta gacaccataa
     3061 atgcagaata aaatcctaat ccaaaatgac ctattatgtc atttgactct tccatcttat
     3121 ccttatattt attaaagaaa tcttcagcac ctgaaaaagc aacttgattt atgtattttt
     3181 ttatctcttc ttcagtcata ccaattccat tgtcaataaa tttaagtgta ccttctcctt
     3241 tatttacaga tactgtaatt ttataatctg atgacttatt ttctgatatt tctcctagtg
     3301 atacaagtct tttatgttta cttactgcat cacatccatt acttataagc tctcttataa
     3361 atatatcttt atcagagtat aaccattttt taattatagg aaaaatattt tctgtatgaa
     3421 ttgaaatact ccctttttca aattccattt tttatccctc ctcattttat aattaatatt
     3481 ttaaatttt
//
LOCUS       DAEOTL010000176         3462 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEOTL010000176 DAEOTL010000000
VERSION     DAEOTL010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3462
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.179"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            373..627
                     /locus_tag="KRH82_003868"
     CDS             373..627
                     /locus_tag="KRH82_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657116.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            663..986
                     /locus_tag="KRH82_003869"
     CDS             663..986
                     /locus_tag="KRH82_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657117.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1260..1412
                     /locus_tag="KRH82_003870"
     CDS             1260..1412
                     /locus_tag="KRH82_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657118.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            1606..2490
                     /locus_tag="KRH82_003871"
     CDS             1606..2490
                     /locus_tag="KRH82_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBG8657119.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAIT"
     repeat_region   2796..3281
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2796..2823
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaa"
BASE COUNT         1403 a          315 c          597 g         1147 t
ORIGIN      
        1 ttagtatgca aaattctgtg aagcaggaaa cctgtgactt tagtcatggg aggttcaggc
       61 tagtattact cattattgta ttcaaaagct aaagtggaaa cctagtgaat atatgaattt
      121 agaagttaat tagagagcat tagcagccga ctcaatactt attaaaattg aagatgaaga
      181 agaaacaatg aaagaagctg aaagagagaa aaagagaggt agaagaaggt agaatttaaa
      241 gttaaaatag ttacattgct aatatatgaa aatgttacaa atttggaaat agatggatat
      301 atatgttgta tagtataatg tagataatat atcaccaagt aaaaaacaac aaataaatct
      361 aaattatgag gggtggaaaa taaagatatt aaacttacaa tatgtatatt tgcttttgta
      421 attggaataa tagtgttatt ttgctgtata ggtctaggtc aatttaatat ggattgtatt
      481 ataaaacaaa atggtgggtc aatagctacc gaacaataca acatatattt agaacaatct
      541 atttcacaat atagaaattt tggttctata ctggttttac taggaggaat aggaatactg
      601 tttgataaaa gtgtcagaaa atactaaaaa agtatatttt tatttaggat gtgatgaatg
      661 atatggcaag agatgtattt agtgtaaaga tgacaccact agaagcacag aaaatggtag
      721 aaaaaaattt ggaagcagat ttagtttctg ttgatattta taacctagaa aataataagt
      781 ctataatagt tacaatcttt gaaaaatatt atgcaagaag caatagtgat gcaggtttgg
      841 tagtgatttg tgaaaatact acaggaaaaa cacttgttaa aattacctca actggtagtg
      901 caattggact atttcagatt gattggggaa caggtaataa tttgattaaa agagtaaaaa
      961 aaatacttat tgattatatt atttaattat tttatgtaga tattcttagg ttggtatgga
     1021 atttgtacta acctattaag taatcaataa aactaaataa acatagaaag cacttacaaa
     1081 tatgtaggtg ctttttattg aaaaaataga aaataaaata aaaagtaaga tataggaaaa
     1141 atatgtaaga attatatgtt ataataattg tagcaagaag atgtaatcta caatttatag
     1201 agtggagttc atgtattaaa aaattatcct cccaacgata agaagggagg tgaatataca
     1261 tggataattt tttatttaat gtgttagcta gtgtaacagc tagttacata gtttatttga
     1321 ttagcaagtt aatcaaaaaa gtaaaaagcc actctaccgc aaagagtgac ttaaagattg
     1381 atataaattt taaatatcat cgtaaaaaat aactttcagt tatagaactt cactctaccg
     1441 caaatagatt gtagttcttc ttgtttttat tataccacaa attagaaaaa atattgcata
     1501 taatattttt tatagtcaat aaaaatatga aattttttat acacaatgat gatgaatcta
     1561 actagatgaa taaatttaat tgtaaataag aaagtactta cttaaatggt aggtgctttt
     1621 gttttgccaa attatgctat aatattgagt gagatgagta atttgtgggg gaattttata
     1681 atgtggatat tagtaccaat aataacaata gtattactta taatagctgt ttcttctatg
     1741 caatatattt tagttatgat agcttttttg ttgattatat attcttttat agaaaagaaa
     1801 atagttatgg gtcttgtgtc agttcttttt ttcacttatt caatttatct ttgtgcaact
     1861 tgggaagata aatccttgat agcagataat aaagttgaga ctgttaaggc acaaagagaa
     1921 actgtagaaa gagaaaaaga aatggaaaga agaagaatac aagaagaagt agacaaagaa
     1981 agatatattg aaaaacatgg aatggaaata tcagaaaatg atttaaaagt taagctagag
     2041 gctttagtac ctcaagaata taaggggaag aaatatgaat taaaagtagg aaaatttaaa
     2101 agatatagta tgtattttga tttaactgta caaaatgaaa aatttagtaa ttctgaagaa
     2161 tgtaaaaaat ttgtaaaaga aattgctaat gatcttaaaa aaattaaaat aagcaaggcg
     2221 tactttaagt ttcattcaaa agatgacggc ggtatatata attctgttta tattgattat
     2281 tttagaaaca tacaaaataa tgtagataat gttgaaaatt tagaattcaa tgagtttgaa
     2341 cttaaaaccg aagaagaaga gaagcgagaa caagagaaaa tagaacaaga aaaaaacagt
     2401 tataataact acattcaaaa cagagtggtt gacccactag atagaataaa gaaactaaaa
     2461 gagttgctag attcaggagc aattacatag gaagaatata ataaaaagaa aaaagaatta
     2521 ttagaataga taatatagta agcacttaca ggtatgtagg tgcttttaaa tttacaaagt
     2581 attccatttt aattttatag tttagatttt atgatataat aaaaatatag aagttttgca
     2641 gtgtgcgata tttgttacaa agtagggctt aatacttgaa atctaagatg ttgagggtgc
     2701 gtgataagtg ttatcaattg cactattgcc ccctcactgc aattttaaga gtattgtata
     2761 tatgtaggta ttggaaatgc taagtttatt ttggggtttt agattaacta tatggaatgt
     2821 aaaaattttt gacgctatga agaaatttac tacaaaattt gttttagatt aactatatgg
     2881 aatgtaaaaa cttttttcat cctcccaaac ctcttgttcg ctgtcgtttt agattaacta
     2941 tatggaatgt aaaaaagaaa ataagtttaa aaaaaggttt cattattata tcgttttaga
     3001 ttaactatat ggaatgtaaa accaattatg tacagtttag ttactgtgtt aagtcttgtt
     3061 ttagattaac tatatggaat gtaaaatcct tttataaata tcttctgaca tgtgtatatg
     3121 cttgttttag attaactata tggaatgtaa atcggctaca acggtataaa ttaaatttag
     3181 cagggtacat tttagattaa ctatatggaa tgtaaattgc tgtgatttca ataataaaac
     3241 aattaataat tgtgttttag attaactatg tggattcaaa attaaataaa caaagaaagc
     3301 acttacaaat atgtaggtgc ttttattctg ctcaaaattg gtcggttggg taaaataatt
     3361 agaaaaagtt agtaaaaacc tattgactgt aactcgttac aatattgtta ttaatgtaac
     3421 gagttacaga aaagaggtga ataaaatagc aactaaaagt ag
//
LOCUS       DAEOTL010000177         3402 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEOTL010000177 DAEOTL010000000
VERSION     DAEOTL010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.181"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            208..495
                     /locus_tag="KRH82_003872"
     CDS             208..495
                     /locus_tag="KRH82_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657120.1"
                     /translation="MKKILYALYSFIVIIANFRLKEKNYNFILLAIFFILLLIQNGVL
                     KTGYQNRATFYQDNYFNGEDKNDKIKFMTIKIFIFLSLPLCFNILFNYLTS"
     gene            complement(1034..1585)
                     /locus_tag="KRH82_003873"
     CDS             complement(1034..1585)
                     /locus_tag="KRH82_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657121.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            1776..2738
                     /locus_tag="KRH82_003874"
     CDS             1776..2738
                     /locus_tag="KRH82_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBG8657122.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIILTLNDSGLKYLSTDLYEEL"
     gene            3033..>3402
                     /locus_tag="KRH82_003875"
     CDS             3033..>3402
                     /locus_tag="KRH82_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HBG8657123.1"
                     /translation="MQKRILRNFIFTGKNILNKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICLNKSIKYEKIGLFELFKI"
BASE COUNT         1340 a          338 c          507 g         1217 t
ORIGIN      
        1 ttagatataa aaaataatta ccttataaat agattgaaat ttatgaatat tcatactata
       61 atttaaatat aaggagatgc cctttgaaaa taaaaattaa aaaatattta atgctactac
      121 aataggaact agaactacac ttaataaata tacagaaatt agatttggct caatataaaa
      181 tacaaatata gaatttaggt gttttttatg aaaaaaattt tatatgcttt atatagtttc
      241 attgttatta tagctaattt tagattaaaa gaaaaaaatt ataactttat tttattagca
      301 atctttttta tattgctgtt aattcaaaat ggagttttaa aaacaggtta tcaaaataga
      361 gctacatttt atcaagataa ttattttaat ggagaggata aaaatgataa gataaaattt
      421 atgactataa agatttttat atttttgtca ttaccattat gttttaatat actattcaat
      481 tatttaacct cttaaattat atttagatat aggagtctta tgataaaagt aagcttatgt
      541 gttatttgta gtaaatataa agtgcatata gtgataaaac aaaagtttca tataaatgaa
      601 gaaaaaaata taaaataatt tatttaacta cttaaaaata aactaaaagg gataataaaa
      661 tagcttttag gttatggtaa taaaggtatt taaaaagagt gcataagcac tccaattgtg
      721 agaaatacat acacaaatca ttattacaac aatgaaaaat gtacatataa gagacgtttt
      781 gtatttgttt taagtgataa tattttaata ctaactaaat aattatcaca atagtaaaaa
      841 agaaaaagga gtattttgta ctccatttgt caaaaatata aaacttttat ataagcttat
      901 tataacataa ttgataaaag tgtaaagata tataatgaat ttataaagaa aaataaaata
      961 aaaaagataa atcctaatca aaggatttat ctttttgtat agaaaataat tattctatta
     1021 ttaaatggca tggctaaact ggataataat ttattattac tgctttcaat gttttttctc
     1081 cttgattatg gtatgtatga attgattcag ctgaaaaaca aatagagtca ttttctctaa
     1141 gttgataaat agagtcattt acttctaatt ttaattgacc ttctataatc ataatatatt
     1201 cctgtgattt ttcagaatga ccaacagatg tataactatg accttcttct aattccattt
     1261 gaaataattc gaagtttcta gttggtgtat tgggataata acaataaaga cgataatctt
     1321 tattttctga aacttgtaca tctatatcag tttttgatac aataaaagtt tcattttgag
     1381 gttgttccag tattgcagta tatggaacat ttagtccact tgcaattttc caaattgtgt
     1441 ttactgttgg gtttgagtct cccttttcaa tttgagaaag cattacttta cttacgccag
     1501 ataattcagc aagttgacct agacttaagt tacgttcatt acgtaatcta tttaaatttt
     1561 tagcaataac agtattaata ctcatagtaa ctccttaaaa tgtaaattat tgacaaatat
     1621 aatttacgaa tgtataattt atttaacatt atttataatt tacaaatgta taatataatg
     1681 aacgttaaat acactgtaca tccgtaatat aaattatact gcataaagag ttgtttttca
     1741 acggatgata gttgagagat taagggggaa ttgtaatgcg tgtacttaat aatgttacag
     1801 aggctatagg caatactcat atgttacatt tatccaaaat agcagatgaa tttggagttc
     1861 aaggtaatat ttatgcaaag atggaatact taaatccggg atttagtaaa aaggaccgtg
     1921 tagcattaca aatgattacc gaagcagaaa atgcaggttt attagttcca ggtcaagcag
     1981 ttgtggaatt aacaagtggt aatactggaa caggactagc aatagcttgt gcatgtaaag
     2041 gatataaatt tatagcgtgt atgtcaaaag gaaattctat ggaaagagca agaatgatga
     2101 aagctttagg tgctgaagta gttcttgtag accaaatgcc taattcagtt catggacagg
     2161 tatctggtga agatttggca cttgtagaaa ttgaggctca aaaaatagca aaagaaagaa
     2221 atgcatttag agcagaccaa tttaatttag aagcttgtaa tcatgcacat gaaaagtata
     2281 cagcagaaga aatgtgggaa caattggatg gaaatattga tgtatttgta gattttcttg
     2341 gaagtggtag tacttttgca ggatgttcaa aaacacttaa aaaacataat tcttctatca
     2401 aatgttatgt tgttgaacct gaaacagcag caatttattc aggtaaagaa ataactgacc
     2461 aagggcataa aatacaaggt ggaggatatt ctatggattt gccattagta gacaagaaac
     2521 ttattgatgg ttatattcaa gttacagacg aggaggcaac tgatgtagca agaaaattag
     2581 ctaaattaga aggtgtattt gcaggatttt cttcaggggc aaatgtatgt gcagcaatta
     2641 agttgttaaa gagcagtgaa aaaggaaaaa atataatttt aactcttaat gatagtggtt
     2701 taaaatattt aagtactgat ttatatgaag aattgtaata atagcacaat agttatgcaa
     2761 tgttttttaa attaagtata tagatttaaa ttataaaaag tatctcaatg taatttttga
     2821 aagttataaa ggagatactt ttttattttg taaatatgga gtatcctact tataagtatt
     2881 aagctatata gatattgatg attagctatg caataaaaaa gagtatgtgt ttttgcattt
     2941 atacatcata acttggaata atacatatta atgttctaaa tgtatttaaa atatatgata
     3001 aaattagaac aaatagatac aaggagataa aaatgcaaaa gagaatttta agaaatttta
     3061 tatttacggg taaaaatatt ttaaataaac ttgtttttat aataaaatat aattttagta
     3121 cattaatttt atttgaatta tttcataaag gattagcctt attttttata tggccatcta
     3181 ttagatatat atttgatatt ttaataaaaa gtttacatat agtctaccta aatatggata
     3241 attttataaa agttttgacc aatcccatgt caatagttct gataatacta tcagttataa
     3301 tactagcttt ttatgcattt tttgaattta cctctgtaat tatttgttta aataaatcga
     3361 taaaatatga aaaaataggg ttatttgaac tctttaaaat at
//
LOCUS       DAEOTL010000178         3359 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEOTL010000178 DAEOTL010000000
VERSION     DAEOTL010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3359
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.182"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(302..523)
                     /locus_tag="KRH82_003876"
     CDS             complement(302..523)
                     /locus_tag="KRH82_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBG8657124.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            1103..1360
                     /locus_tag="KRH82_003877"
     CDS             1103..1360
                     /locus_tag="KRH82_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8657125.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            1829..3066
                     /locus_tag="KRH82_003878"
                     /pseudo
     CDS             1829..3066
                     /locus_tag="KRH82_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
BASE COUNT         1385 a          300 c          508 g         1166 t
ORIGIN      
        1 agtgtttcaa ttgtcaatat tagtatttta attgttgact ctagttattg ctgatataga
       61 aaatatttaa tttatttcaa ttaattagat taaagtaggg tagcatctaa aatagctaac
      121 atgtttaagt tgaaatacgt ttaatatatt aatttttcaa agcgttaata tattaaagtt
      181 ataaccaaaa ttgaagttat aatctgccaa atctatagcg tattaagtac gttatataac
      241 ttaatctttt atataaagag ttaatttttt aatttgtaaa gcagagtacg tttaaaagat
      301 actatttaga tagtgatgta ctatctaatt ttaaaatatc tacaataggg ttctcttgaa
      361 gacttgctat tgcttctgca acagcataaa catcttcatt taatgcctct gcttttacat
      421 ttgcaaatga tttactttta acaactgcct tacccttatc atcaaaacca gcatccaatt
      481 ttagttttat actagataaa ttttttgttg aaacaacttc cataaaatta cctcctaaaa
      541 atttaatttc aaagatttgt cgactttctt tgttagctat aatactatca tctaagataa
      601 tatcggagtt aaacagtaat ttctaaagat tttttgtgta aatttttata ggaaaaattt
      661 tacttttttg ctgatgaaaa agtttacaag ttatttgtga agatatgttc ttagtgtttt
      721 gaaatagtat ttgtatatat tcctgcttag ttgagatagt tttgtatgga ttttcatatg
      781 tgtagagtta aatgttaggt actaaagttt atgttaaatt aaatgttaaa gcttatgtta
      841 aaaattttat taaatttaat ctgtaaataa aaaagttaaa agtccaatat taacatttta
      901 cttttaaacc attaaaatct ttattaaagc taacaaagtt ataagttatg agaaatttta
      961 ttgaagttaa tacaaaaatt aattttaaag ctaagaaatt atttattaga ttcaataaaa
     1021 ctaataaata tagtttagtc aataatgtat taaataaaaa ctttgttaag tctataaaaa
     1081 tatcttaaag gaggtgtaac ttatgaagat aaaagtggag gatataccag ttcaatttca
     1141 tgcaatggta gaaataattg gaattgataa gtttatagag gttgccaagt tgtatggagg
     1201 aacaaatact tatataccta cgtataaggg gctttttaga tatgctagaa atagggatat
     1261 agtaaaacaa tttaatggag tcaaccacaa tgaattggct attagatata atatgtgtgt
     1321 aagcaatatt aagcgaatac tcaatgaaaa tagtgtttaa atataataaa ataatgttta
     1381 aacataatga aaatagcctt gttaaacgta agagtaaaga caaagaagat gttttataaa
     1441 gtttttttag acaaattaac taaatttact acttattaat ttaaatacat tgtatattct
     1501 ataaaaaaat ttgttaaata ctggagatat attgagaata caaagaaaat ggtcgaaaat
     1561 atttgttggc taaaaaatag ataaaatgat acaattgctt gtataaaggg gaaaaataaa
     1621 caaataaact atataaataa agaaatagca attaatatga cataatatat ttataaaatt
     1681 aagaatataa atagatattt taaggtatta gttgttaaat taggaaatat taaaaaaaat
     1741 atatatttat atttaaacta ttttgttatt tatataaaaa tacttatcta gttactagca
     1801 attattagta gaaatggggg aaatagagat gaataaggga ttttacaaat taaattcagt
     1861 ggtattgaac tttgatatta agaatgatgt taacaagata agatttaatc attatataat
     1921 gagaaaagaa aacatacaaa gacttcaagg aactctgcca aacggacaat tttatatgac
     1981 agtgagaaga gctgctacag atttacaact ttctatttct actataagta ggcttgtaaa
     2041 agagtttttg gatttaggga taataagatt agtgtctaag ggtgtaaaag gtaatcgttc
     2101 tgtatatagt tacgtaagta tagagtttaa tggaagttta tttgatgata gtaaatatat
     2161 ggaacttgac tgtgtatgta atgatgaatt tattgataat agtggcatag agtttgattg
     2221 tgatagcaaa gataattctt ttaatggaga tataaatgta gaaactgtgc attgcattaa
     2281 tgagtatttc tctgatgatg atgtagagca taattataac aatttctata acaaagatac
     2341 tatgaaggat aaagccattt ctaatattag cactatcaaa aaatatattg atgaatcttt
     2401 tgatacaaat aaatcagaaa attctaactt acaacaggag tcaataaatt tcaactttaa
     2461 tgatacatgc aatgaaatag ataaaagaac gaataatagt atagaaaata atcaaaataa
     2521 aaggcctatg agattgagtg acatcagtgt tttaagtgat aaaggtatga caaataaaaa
     2581 gaattacttt aatcataatc atggtataca aaaagggact aaatctgtaa caaagaaaaa
     2641 agaatcctta aataaattta ataaaaaaat atacagcaaa gcattataaa tatgctaaat
     2701 aaaaaatcag gtaagaattt taaaatcgat tctccaataa gcataaaact tatcaatgaa
     2761 aggctaaagg aaggctatgt cttagaagat ttctacaaag ttattgaggt aaaagtggct
     2821 aagtggaaaa ataccataat ggaaatgtat ataagaccag aaaccttgtt tagctataag
     2881 tttgaatcct atgtaaatga aaacatatct atgaaaagtc aaagtaatgt tcacccatgt
     2941 aaagaaggca atagtaatga tagcagtaat tatatacatt ctgattatac aacatatgat
     3001 ggcagtgtgc gtgagagaaa aaaatatgag aatgtaagat actggaatcc tatatgtgaa
     3061 atttaattag tttaagaatg tatttatgat aaataagata ttaatagaga atagtgagct
     3121 atagcaaatg atatatcaat agttggtagt aagttatatt aagcaagata ttactatcag
     3181 gtagtgaatt gtattgaacg atatatcaat aattggtagt aaattatatt aagtaagata
     3241 ttactatcag gtagtgaatt atattgaacg atatattaat aattggcagt aaattatatt
     3301 aaataagata ttactataga gtaatgaatt atattgaacg atatattaat aattggcag
//
LOCUS       DAEOTL010000179         3296 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEOTL010000179 DAEOTL010000000
VERSION     DAEOTL010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.183"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(12..377)
                     /locus_tag="KRH82_003879"
                     /pseudo
     CDS             complement(12..377)
                     /locus_tag="KRH82_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(398..1477)
                     /locus_tag="KRH82_003880"
     CDS             complement(398..1477)
                     /locus_tag="KRH82_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBG8657126.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1531..2820)
                     /locus_tag="KRH82_003881"
     CDS             complement(1531..2820)
                     /locus_tag="KRH82_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBG8657127.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGALLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(2983..3194)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1092 a          660 c          359 g         1185 t
ORIGIN      
        1 gctatttttt aatcaaactc atatccacca gataccaata ttgaatctaa ttctattttt
       61 tctcttaagt cttctggcca atctataaat ggaagaatgg cagtagtggc tggctttcct
      121 attcttatca tagccacatt attaagtctt tttctttcta caatagcatt tgtacaatga
      181 gttgtaccaa gcatagcata ttttattaat gaatggtcaa tcttactttc atctataact
      241 ttttttaagg cattgtaaac accagtttca acatcttttg tagttgccac cttaactgaa
      301 tgaattactt ttaattcccc atccagtata caagcatctg tatttgttcc tccaacgtca
      361 attcctacac gatacatcaa aatttcctcc taaactttta ttttccttgt aattcttcta
      421 ctgttttata ttccacatca tatccaaagt atccaggtcc aactgtctca attccttttt
      481 ctgttctcca cttttcatta caaggaaaag ctactaccat aacacgagag ccatatttta
      541 ttctctctgt agttattgga aatccagttt ctaaatctaa tactgctatt aaatctggtg
      601 taatacaaag tggtgtatca ccttttttgg caattaaatt ctcattttgg aataatatag
      661 aatactctcc atcatactca ttaatcccag caaaaaaggc atgtcctcta gtaaatccac
      721 ctttcaactc tctcttaata tcaattactt ttccttcaaa taacttgtat ccacgcaatt
      781 cttttagtat attctcaaca gcaccttttg aatcagattt attttcaagt aaaaaccctc
      841 ctatagtttc agctattgta agagtattac ctatagcagc ttttttaact tgagctccac
      901 ttaaattata gtcactaata gaagaacttc ctcccatttc tacagttaaa gttctagcta
      961 atctttctga ccaaattcca tccacaggat aaaggatggc agaattacct ttttcatcag
     1021 acattacggc aggagatgcc tcatatcctt caagataaaa agttaccatt tgagcttcag
     1081 ggaaagctct acccatagaa tctgcatcta agataggaag tcctttttta gcagcaactg
     1141 ctataggcat aagtgagttt atccctccta tttctatagg aattataaca tccacttttc
     1201 tatttaataa tttctccatt atttctaaag gggtagttaa ctcaacttct gaaagtaatt
     1261 tttctattgt aattacagga gaacccatac cagatactgg aactaccaaa gcatcatcat
     1321 caagttcatc taaacttatt acttttacag gaccatactt tttaatggct tgttttgcaa
     1381 ccaatttacc tacatatggg tcacctccac ctccagttcc aagcactgct gcaccaactg
     1441 ctattttatc tacactttct tctgttaaaa atctcatgtt actttctcct catatttcta
     1501 atttatttta tactttataa acaaatttct ttatactgct ttgtctattt cttgcttatt
     1561 ttttgttgaa caaagcactt ttccaataat agattgtact acaaaccctg ctataaaacc
     1621 atctaaaggt gctatagtag taagagttat aaatccatat gttgaaaggt aagttattaa
     1681 tataccaatt atccaagaca ctattgaacg tttaactatt ggtttatata atactccttt
     1741 atcaaagcct ttaagttctt gctttactat gtaatattct gctgtatata caccaccaac
     1801 aggtgcaatt acaattccaa gtaaatttaa aaatcctata aaaccttcat atattccaaa
     1861 tacagccaat aatgttgcta taataccaag gactatagtt aatactttct caggagcctt
     1921 cttaagtaca agagctatac ttaatgatgc tgaatataca ttacttgtat ttgtagtcca
     1981 ttgtgctaat gtaagtacta ttatacctgg tatagcaatt cctaatgtaa taaaaattct
     2041 cataatatct gaagttccca tacattttac taatactatc gaaactatta tcataaaagc
     2101 atttccaaat tgtattccca aaaagcttga aagagcacag tctcttctac ttttagccca
     2161 acgacttata tcaggagata caattgcacc aactattatt atactcattg acagagaaac
     2221 tccacctgca aatgtcatag tagatttcat attatcatca actgaaattc catttgctct
     2281 aaaagctaag aatatagtta gcatcataag aactaataaa aatggtactg aatacacact
     2341 caacttctcc attgccttat atccataaat tgcagtactc atcatcaaga gagcacctat
     2401 taggcttaaa atctgcatac ttacatctaa attaaatata tcttttatta ttatctgtgc
     2461 attttgagca aagaaaccta cttgaactcc aaaccaacct aatagagaaa cccctataac
     2521 tagagaaaat atttttgctc cagcttctcc aaatacatac tttgttatca tagatgtaga
     2581 taaacttgta gatgaaccaa ccaaagagca tgtagtatac aaaattgcag aaaaaaatga
     2641 accaacaatt actgacaata ttgcttgttt cattggcata ctctgtgcca actcagcgcc
     2701 taaaataaca gatgataaat ccacacctat tgctactaaa actgaaaaca tagctaccca
     2761 accacgtttt tgattctctg gaatctgttc cagagcatag ttaatttttt cttcttccat
     2821 tttcatccct ccatttaaat cgtaaaacta ctgaccttag catattttac aattttctaa
     2881 tttataaatt tattaactat catattttta taattttcat ttaatatata gttttaaatt
     2941 ttctgaaata agtttataat aaaaaacgcc tcttggaaaa atccaagaga cgaatataaa
     3001 tccgtgttac cactcttatt agtaaaaatt aattttactc actcattttc ttaaggcgaa
     3061 ttaaaccact attctaacat aattacaata gtattctcca aagtcctttt cacataaatt
     3121 ccaatattag ttctcagcca aatctaactc tctgtaaaat tcctttatgc tactttcttc
     3181 ttctacgaat atataatatt gatttgtagt taatttatga tttatatcat aatatatatg
     3241 caatattttg tcaacttaaa aagtcaatta cttgcatttt ttaattttat atgtaa
//
LOCUS       DAEOTL010000180         3177 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEOTL010000180 DAEOTL010000000
VERSION     DAEOTL010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3177
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.184"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            111..689
                     /locus_tag="KRH82_003882"
     CDS             111..689
                     /locus_tag="KRH82_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBG8657128.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNKLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            980..2230
                     /locus_tag="KRH82_003883"
     CDS             980..2230
                     /locus_tag="KRH82_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBG8657129.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            2391..2960
                     /locus_tag="KRH82_003884"
     CDS             2391..2960
                     /locus_tag="KRH82_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBG8657130.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVNELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         1199 a          415 c          458 g         1105 t
ORIGIN      
        1 ataaacataa atcacttgac aaatttataa gtagacaata ttatatatct atgactcaaa
       61 atattttcaa agtcatatat atcatatata gacagaaagg attgataaaa atggctaaaa
      121 gttttacaga aatagaaaaa gacaatataa gaaaaagact aatttcagaa tgtgaaatca
      181 actggtctaa atatggatac aaaaaaacta atattgatga actttgttca aaatcaggaa
      241 ttgcaaaggg ttctttctat acattttttg attcaaaaga aaagttattt tttgaagtat
      301 taaatggaat ccaaaacaaa cttatatcat cagtagatga aattttaagt aacatgcctc
      361 caaaagaagg ctttgcaaaa tccttaaaaa tgttatatcg attatatgat aaaaatccat
      421 ttttatattc accaaataat cctgatttca tcagcctaat aaataaacta cctcaagata
      481 tgtttttaca acttgagtcc aataacatac aaagttttta cgacttaatt gagagacaca
      541 atctcaagtt gaagatagaa aaagaaaaag tttttggtgt ttgtaatgct ctactatcaa
      601 gtctattggt aaaagaaaat attgaatata actatattga agtgtttgac tttatggtgg
      661 ataatcttgt agaacacata cttgaataac aatttaaaat aatttttcta agtatttttt
      721 tatactaaat aggattaata tgattgaatt aatgaaaaaa ataaacaata taatttataa
      781 aataaatgat aaactaaata tcacacaaaa cttatagacc ctagagcaaa cccattccac
      841 tctactctaa gccatctata atagtttgta tatttctaat aatattagat attaaagtaa
      901 gaaaaaaatt ccttataata attgctatta tatcaattat tataaatatt ttaataatct
      961 tagataggta ggtacatata tggtaaaatc ctcgaacact tttaataaaa acttcaactt
     1021 gatgatatta ggtcaaataa tctcattgtt tggtgcatca atactcaagt ttgctttgtc
     1081 tttatacata cttgatataa ctggtaaagc agaaatattt gctactatac tagcagtatc
     1141 ttcaatccca attatagtat tctcccctat tggtggagct attgcggata tattcaacag
     1201 aagaaactta atggttattt ttgatttttc aagtagtctt acagtactaa tcttagcagt
     1261 attcttattc aacaataatg gttcaatatt acttgtagga attattatga ccatattatc
     1321 agtcataagc acaatgtatc aaccaactgt tcagtcaagt acaccccttt tagttgataa
     1381 tgagcattta atgaatgcaa atggtattgt agctggagtt gcatctctta caaatattgc
     1441 aggacctgta ttaggaggtg tcttgtatgg tgtgattgga attaatgcaa ttatagttat
     1501 aagttgtgta agtttctttc tatctgcaat tatggagata tttatacaga ttccttttat
     1561 caaacaagag caaaacagca acattataaa aactatattt actgatataa aggatggtat
     1621 tgttcatata tgtaaagaaa atagatttat actaaaaata ctttttttag ctatagcaat
     1681 aaacttattt ttaagctcta tgttaatagt tggtatcccc tatatagtaa aaatcactat
     1741 gggagctagt aacttcttat atggtctagc agaaggagca atttctttta gttcactggt
     1801 agctgctgtt agtattggta ttttctcaaa acatctaaaa atcactaatt tgcacatttc
     1861 ctttattata tgtgcagtta tgttcatacc aatggcggtt tcagtatatc catttatatt
     1921 aaacacagga tttccagttc catttttaat ctttatagta tcatctatgc taatattttt
     1981 tacaacgact cttatctcaa tatatgttat aacagtcaca caattaaaaa ctccaaatga
     2041 actcttagga aaagtaatgt caattctttt tgcaggaaca gcaattgcaa tgccccttgg
     2101 tcaggttatg tatggtaaac tttttgattt attatcagat agagtgtaca tcattatact
     2161 aggagttgga tttattacat tacttatagc atttgtatca aagataacat tgaggaacga
     2221 aaatctttag atacaaagaa tttagatata aagatttaat tttcactaat ttctgaattt
     2281 aaatgcaaaa ttgtgtatca gtatgttgac gttttagaaa ttgattgata taatcaatgg
     2341 aaaataaact ttataaaaat tcaaaatatt cagctagagg agtgataaaa atgagttaca
     2401 tgccaacttt agaacaagca tgggaaatat taagaaaata caataaggaa gaatttcata
     2461 taagacatgc tcaaattgta tctggagtta tgagatacta tgcaaaggag tacgaccctg
     2521 aaagagtaga attttgggaa atagttggac ttttacatga tttagatttt gaaatgtatc
     2581 ctgatgaaca ttgtgttaaa caaagagaat taatgacaga gcttgattta gataaatcaa
     2641 taatcgattc tacaataagt catggatatg gattaactgg ttcagatgtt aaaccagagc
     2701 aatttatgga gaaagtatta tttgctgtga atgaacttac tggtttaatt ggtgctgctg
     2761 caataatgcg tccttcaaag agcgtttctg atttagaatt aaaatctgtt aagaagaaat
     2821 ttaaagataa atcatttgct gctggctgtt ctcgagacgt tataagaagt ggtgcagaaa
     2881 tgcttggatg ggaacttgat aagcttatcc aaacaactat agaagctatg agaagcttga
     2941 ttccagagat ggcaatatag ctcctccata catataccat agaagttaca tctttaaaga
     3001 gcatttctct ttttgatgca acttcttttt atattttgta gaataaaaag tttaatattt
     3061 taaactcact atataatcta taataaatac tataaataat ataatgtata atagttataa
     3121 actttctaac cttaaaagtt tctaatactc aataaacaat tctaatatac aaatgtc
//
LOCUS       DAEOTL010000181         3064 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEOTL010000181 DAEOTL010000000
VERSION     DAEOTL010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3064
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.185"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..280)
                     /locus_tag="KRH82_003885"
     CDS             complement(<1..280)
                     /locus_tag="KRH82_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657131.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDIPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQIT"
     gene            complement(398..901)
                     /locus_tag="KRH82_003886"
     CDS             complement(398..901)
                     /locus_tag="KRH82_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657132.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GICEIPY"
     gene            complement(919..1422)
                     /locus_tag="KRH82_003887"
     CDS             complement(919..1422)
                     /locus_tag="KRH82_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657133.1"
                     /translation="MQETRVLVETRETTGEETTSYWFDLPIDVAEFEEKLGVGAESTA
                     YRIIEKVLPYADEVHEHTSVYQLNELEFMYRQLSSDMQEEYVSLLTVFENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDSTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(1341..1637)
                     /locus_tag="KRH82_003888"
     CDS             complement(1341..1637)
                     /locus_tag="KRH82_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657134.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWREMKRLSPADYEERQL
                     EDFSKFVFGIPYQTLKDVMKQQKGREEQCRKQGCWWKREKQLAKKQHHTGSTCR"
     gene            complement(1722..2498)
                     /locus_tag="KRH82_003889"
     CDS             complement(1722..2498)
                     /locus_tag="KRH82_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657135.1"
                     /translation="MSLGEKIFKLRKEKGISQEALAEQIGTTRQAISKWENNQGFPET
                     EKLLQLSNIFEVSTDYLLKDEKNVKNSEERGYYVSKEMSVGFIANQKKLGLYLALGVM
                     LCIFAGIPYTLFLDNMTWRYLGMAFCFVAGIIFFVVAIFYEKQEYNILRQEPLLLDYE
                     YLKELKSEYTSKKKKYVIVAVPCTVLFIAGLIFFLFTVKGYISWTEYHSFAFFGLAVG
                     MLGFVYTINVMETYELLVKNEQYSTSFFFKLKRKIKKRLG"
     gene            complement(2702..2923)
                     /locus_tag="KRH82_003890"
     CDS             complement(2702..2923)
                     /locus_tag="KRH82_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657136.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(2924..3058)
                     /locus_tag="KRH82_003891"
     CDS             complement(2924..3058)
                     /locus_tag="KRH82_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBG8657137.1"
                     /translation="MWVLLKDFLLVSMGMGIGIVLMCILNVGKEADYKMKQLEESEDN
                     "
BASE COUNT          925 a          666 c          480 g          993 t
ORIGIN      
        1 aggttatctg tgatttcaaa aagctgtacg gcttctttcc gtcaaaggtt ttctgcgaca
       61 taaaccaagt gagagcaacg ggaataccga agtatttgag aaatgctccc tcaatcatgg
      121 aaagtggggg aatatcccca aacagaatga tgataaattc cgtaatcaca aaccatgtaa
      181 tctgtgtaaa ggtaacggga aaaggcaggt taaagtcatt gattgcatac aagacttttt
      241 ccacgttcca gatacccgta taagatttaa tctttttcaa gttctttcag ctcctttcgt
      301 aagttcttca aagagaaaag gacagccatt ttcagactgt cccttaaaag agaaatacgc
      361 tgtcagtagc aaccatgccg ttgctgatct tccagcgtta atatggtatc tcgcatatcc
      421 ctcggcttgt ttcaataaag caaccgccca tatccaaatc tcgcccgtag gcttcataat
      481 caatgtagtt ctgtaagctg ggtggaatgt ccccaagtgc ctgcaattcg tctatgtagt
      541 aataggcaac atctgtcatg gtttcacagt cgggataata ataaatatcg tccttgtgtt
      601 ccacgacttc ttccagcgtc ccgtagtgac tgataaattc gtccagacac tctacgatat
      661 agtcgggaag ttcctctatc atttcataca tctcattgag ttcttcaatg gaaacatact
      721 cgccaatcgc aatggggaag ttgtcggtat catggatagc gtattcctca tactgttcat
      781 tcaagccgat tttttctttt acatcttcct cgtcaatggg gaacgtgaac caagcaccga
      841 ctaaataacc ctcattgtat ttaccgagat tagcaatgta aaccgccata tcatctatca
      901 taagcaccac ctcatttcct actctggtag ttcaaagata ccgtgttccg ttactaagaa
      961 tttcccgtgt tcctgcaagt gagaagcgta ggcttcaaag tcaaagtagt attcttgaca
     1021 gtcctcggat aaatgtttga acgtcgagtc attcatcagc ttttgccttg caacatctat
     1081 catgcttttg cagtcgggat aaaccgtaat cacgttcctg caaatataaa gtgcttctaa
     1141 attctcaaac accgtaagta gtgatacata ttcttcctgc atatcgcttg aaagctggcg
     1201 gtacataaac tctaattcgt taagctggta cacgcttgta tgttcgtgga cttcatcagc
     1261 ataaggcaac accttttcga taatgcggta cgccgtgctt tctgcaccga cacctaactt
     1321 ttcttcaaac tcggcaacat ctatcggcag gtcgaaccag tatgatgttg tttcttcgcc
     1381 agttgtttct ctcgtttcca ccagcaccct tgtttcctgc attgttcttc acgtcctttc
     1441 tgttgtttca tcacatcttt taaggtctgg tacggaatac caaacacaaa ctttgaaaaa
     1501 tcttctaatt gtctttcttc ataatcggca gggctcagcc gtttcatttc acgccacacc
     1561 ttacgcttgt aagagggcag gtcagaaatg tattcacagc cgacttttgc ctgcatatcc
     1621 ttaaaaatat cgttcatgta atcactccaa tctgaaattt tggtatgaaa aaagcagtca
     1681 atcataagac taactgcttt gtgtgaatat taaattatag cttatcctaa tctcttttta
     1741 atctttcttt ttagtttgaa aaagaaactc gttgaatatt gctcgttttt cactaatagt
     1801 tcataggttt ccataacatt gattgtatat acaaaaccca acattccaac agcaagaccg
     1861 aaaaatgcaa aggaatgata ttctgtccat gaaatatagc ctttcacagt aaatagaaag
     1921 aaaattagtc ctgctataaa gagaacagta caaggaacag caactattac atattttttc
     1981 ttttttgaag tgtattcgct tttcaattct tttagatatt cataatcaag tagtaaaggt
     2041 tcttgcctta aaatgttgta ttcttgtttt tcataaaaaa ttgctacgac aaaaaatata
     2101 attcctgcca caaagcaaaa tgccatacct aaataacgcc aagtcatatt atctaaaaac
     2161 aaggtatatg gtattccagc aaaaatgcaa agcataaccc ctaaagcaag ataaagtcct
     2221 aattttttct gattagcgat aaaccctacc gacatttcct tgcttacata atatcctcgt
     2281 tcttcactat tctttacatt cttttcgtct ttcaaaagat aatccgtaga tacttcaaaa
     2341 atgtttgata attgtaaaag cttttctgtt tctggaaacc cttgattgtt ttcccattta
     2401 ctaattgcct gcctagtagt gcctatttgt tcagctagtg cttcttgcga tattcctttt
     2461 tcttttctta acttgaagat tttttctcct aaactcattg tgtgatacct cctatgattt
     2521 gatgaataaa ttttatcaag ccataatgtt atattctata ttttttgaaa tgcacattag
     2581 caacttcaag ttgcaacctt gtataatata caaaattcat agatttttct ggtaagtaca
     2641 gcgttttatg taatacaaca ttcaaattat aacattcgca tatcagtacc acaataaaat
     2701 tttatgcacc gataatctta ttgaacagct ctaacaatac atctttcaca ccgccagcat
     2761 tgaataccaa accgacagca atcaaggcaa ctaccaagaa gccgataagt ttggaaaact
     2821 cacgcttgaa ccctaagtag ataccgataa ccacaatcgc cataagcact aagctctgtg
     2881 cgttacttaa aaaccattga tacaaatttt gtccgaaatt catttaattg tcctcgcttt
     2941 cttctaattg tttcatttta tagtcagctt ctttgccgac attcaaaata cacatcaaga
     3001 ctatgccgat acccattccc atagatacca gcaggaagtc ttttaataat acccacattt
     3061 ttca
//
LOCUS       DAEOTL010000182         2848 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEOTL010000182 DAEOTL010000000
VERSION     DAEOTL010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.186"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            80..520
                     /locus_tag="KRH82_003892"
     CDS             80..520
                     /locus_tag="KRH82_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBG8657138.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            536..1987
                     /locus_tag="KRH82_003893"
     CDS             536..1987
                     /locus_tag="KRH82_003893"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBG8657139.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVFTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCFVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(2078..2746)
                     /locus_tag="KRH82_003894"
     CDS             complement(2078..2746)
                     /locus_tag="KRH82_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBG8657140.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSITAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
BASE COUNT         1175 a          265 c          493 g          915 t
ORIGIN      
        1 gaagtattat attatagata tataaacgca tttgagatat aagagggagt tataaatcat
       61 tagttttgag gtgaatgtta tgagcgataa agaattatct attttgttgt tagaaagtat
      121 gaataatttt cataatttaa taaagattat taataacgaa agatataaaa aagataaggt
      181 tcttacagaa agacagttct ttgccttagt aaaaataaga aaacatgata aaatagagct
      241 taaaaatcta agtagagatt tgcatgtatc tacttctagt ctgtgtatac tacttaataa
      301 attggttgag caagagtatg tatataggga agaagatagt agagatagac gaaatacttt
      361 ttatggaata actaaaaatg gagaaaagat attggataat gaaatactaa agtttgtatc
      421 tataataagt gataaaatgg attgcctaga tatagataat aaagataaat tatttacttc
      481 tttggaagag tctaaaaata taatagaaca attattttaa aaaggagaat ttattatgaa
      541 tataaagtat tctaaagaga tattaaaaag tttagaaaat gctataacag tagtagctct
      601 atttgaggga gaagatgttt ttacgacatt tgataaaata aatatgataa gcagaaattt
      661 taattctaaa gaaaatagta tagatactgt aacattaatt gaaaataaca atttggtaaa
      721 tgtttgtttt gttggttttg gtaagagaga gttattgaat agagaaaaaa ttagaatcat
      781 aggtgggaat ttgtgtaaaa aattaaaaaa tatattgaaa aatgaagcat ataagagtag
      841 tgatgttaat gtactgaatc ttaatttaaa tagtgatgaa ataggttgtt ttgtagaagg
      901 gatattactt ggaaattata agtttgataa gtataagaca aaaagtaagg attttgaaag
      961 aaaagaagtt gatactataa ctatatttac tgaaaaagaa gttgagtgtc aaatagaaaa
     1021 ggctaaaata ttagctaatt caactataat agctagaaat ctagttaatg aaccatcaaa
     1081 cgtaatatat ccaaaaacat tagcagtaga aacagttaaa cttggtgcag agtttgggtt
     1141 taatgttgat gtttatgaag aagaaaaaat aaaggcattg ggaatggatg cttttttcgc
     1201 tgtttcaaga ggttcaatta ataaaccaag attcatagta atgagatact ttggagataa
     1261 agaaagtaca gatatattag gtctagtagg taaaggattg acttatgata ctggtggata
     1321 ttctttaaaa tcaaatgctt ctatgctaga tatgaagaca gatatggctg gtgctgcgag
     1381 tgttataggt gctatgtgtg ctatatctca aagtaaatta aagaaaaatg ttatagcagt
     1441 agtggctgca tgtgagaatg ctttatcagg aggttcatac aaacctggag atataattag
     1501 ttctatggca aagaaaacta ttgaagtttt aaatacggat gcagaaggta gacttacatt
     1561 agctgatgca atatactaca ttataaacaa tgaaaaagta acaaaggtgg ttgatgtagc
     1621 tacattaact ggtgctgctt taacattgtt aggtaatgtt gcaactccta tagtaacaaa
     1681 taatgatgat ttttattgtg aattagaaaa agctgccact ttatcagggg aaagggtatg
     1741 gaagatgcca atttatgatg aatttaaaga tatgataaaa ggagaagaag cagaccttaa
     1801 aaacactggt ggtaaaaatg ctggatgtat aacagcagga gcttttattg gtgaatttgt
     1861 tgggaatact ccttggatac atatggatat agcggggaca agtacatcat caaaatcaat
     1921 tggatacaaa gcaaaggggg ctacaggaga acctgttaga acattgtact atttggcaga
     1981 aatctaaaaa acaattataa aatataattt ataaagccac gtggatattt ttgtaattta
     2041 agattatcta tgtggcttta ttttttattt aagtaaatta tttactcttt ttcttttttt
     2101 caagtataaa agtatctcta ttaaataaaa gagcaggtat gtacataata ctagtaacaa
     2161 aaataaacgt aaaaatagca gttatgctat gacttaaaaa accataatag tacctagagt
     2221 tggtaaatgt gtttagtaaa aatatgaatg aaaaataaat aaaacatata gctaagttat
     2281 ctctaagtgc atatctgtta actctaaatt ttctaacatc aaccatatat atatctgcat
     2341 aaattatcaa gcacttagag aagataaaga taaaatatat taagctagga aattcatagc
     2401 ccaagttttt agaaaaaatg agttctccaa ctgaacaaac taaactccaa gaaaaaaata
     2461 tattaaaaag atgatactgc ttaaaaatta gtatggctat acacagatat atacaaatat
     2521 aattgattcc aattggtaaa gagtttagag tactataatt acctgaagaa ataagtaata
     2581 attgctctag agccataatt attacaagta atgtacaaat tatcttctca actgtatagc
     2641 tataaggtaa aatatttttg gttagttttg gacaatagta taaaaataat ccaaatataa
     2701 agagacttac aaattgttca ctagaaaaaa gaaaaatttt aaacatataa cattctctcc
     2761 tataataaat ttaatatgta tctatataaa tatattcatt atatctcaat ttaatatata
     2821 aaaaagataa taatagttag atttttta
//
LOCUS       DAEOTL010000183         2749 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEOTL010000183 DAEOTL010000000
VERSION     DAEOTL010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2749
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.187"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            368..2179
                     /locus_tag="KRH82_003895"
     CDS             368..2179
                     /locus_tag="KRH82_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBG8657141.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAVLSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQIENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVRKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2267..2497)
                     /locus_tag="KRH82_003896"
     CDS             complement(2267..2497)
                     /locus_tag="KRH82_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003171502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657142.1"
                     /translation="MKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTNY
                     SILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1038 a          281 c          402 g         1028 t
ORIGIN      
        1 gtaggtaaat agtattttaa ttatttatta aaatatagat tatgtatatg ccaaatttaa
       61 aaagagacat aaagacatta tacaaatata ttattggggt gatattttat aagaaaagaa
      121 gtgatgcagt aaattaattg agcaatttaa aaatgattta atgatagtgt tgatgaatgt
      181 ttaaaaagaa attttagaaa aacgtatatt gctgtttgtg ttggaggtga tgaatttgta
      241 taatttatag gatataaatg attaaactat ttaagataaa tacatatcac tgtaaaatat
      301 tgataatcat tttttataag agattgatta tttgcaaatt atatatatta caaatgaggt
      361 aacaataatg aagaaaaaat atgatttttt aatttattct gctatttggc tagttattat
      421 tattcttttt atattttctc tatatcatag tatagagcat attaaaatta taagtcacac
      481 tggtactatt cgcagtgaaa ctcaaaaggt tgttaagcaa gaattgaata atgaaagaaa
      541 tgatgacttg ataaaacgac tggataatat tctgataaag ctaagaacag gtaatggaga
      601 aaatggattt caaagatgtg ataataaaga atttcaacaa aaactaaatc aaatggattc
      661 tatgtgggaa tctatgaaga aagaaattat aaaagttaga aatggtgctt caggtgataa
      721 attatataaa ttgagtgaag agtattctgt gttgtctaat caaattgttt ttatatctga
      781 aaaacactct aatgcaaaat tgtattcttt tgctactgca ctatttattt atcttatatt
      841 ctcaacaata agtcttttaa tttgggaata ttataataaa aaaaggttta aaagaatatt
      901 ttatactgat aatttaacaa aaataaaaaa tcaggttgca tttgaaaaca gagcgattga
      961 aattttgcac aatgcatcta acaaagagta tgtactgcta aatattgata ttgacaattt
     1021 taaatatatt aatgatacac atggatatga atatggagat aaagttctaa taatagttgc
     1081 agctgtactt tctaaaactt ttaatatcaa agaaacttgt gcaagaattg gttcagataa
     1141 ttttgtaata cttgcaaaat atagagattc tcttttagag gatattcggg aaatgctaac
     1201 taatgctata atctctgaat tagatatgaa tgtaactcaa actatatctt attgtatagg
     1261 agcgtactta gttgaaattg ataatttagg ttataaatcc atcaattcta taatggataa
     1321 ggcaaatatt gcacacaagg taagtaaaac aagaggaatt tcctccacag tatggtataa
     1381 tgaaaatctg ttaaaacagt tacaaataga aaatagtatt tataattata tgtataaagc
     1441 gatagaaaat gaagaatttc atatgtattt gcaacctaaa tttcaaatat cttctttaaa
     1501 tgttgtgagc gcagaagctc ttgtaagatg gttttctcca gaacttggtt ttttatcacc
     1561 agatgaattt attccattgt ttgaaaaaag tggatttatt attgaattgg acttttatat
     1621 gttaaaaaaa gcgtgttcat ttgtaagaaa aacgtttatg aaaaaaaatc aatatacata
     1681 tccgattgca gttaattttt caagggttac tatttaccaa aatagttttt atcaaaggtt
     1741 tttagatact gttaaagaat atgaaattcc ttttaagtat atagagatag aggtaactga
     1801 aagtgctttt aatgaaatat ctcaaccagt tatttcgatt ttagaggagc ttaaaaagtt
     1861 aggattttta atttcaatgg atgattttgg atcaggatac tcttcattaa gtcttttatg
     1921 ttctctatct attaatggat tgaagttaga taaaagctta cttaaagaaa catttaaccg
     1981 ggagaaagta tatagtatta ttcagtgtat tattgaaatg tcacatcgta taggcatgtc
     2041 tgttgtatgt gaaggtattg aaactaaaaa agacttggaa tttttaaata cagttaaatg
     2101 tgatgtagga caagggtttt atttttctaa accgatagaa gaaaaagaat tttttaacaa
     2161 atatgtaact aaaaaataat ataattattt ttatcagtct atacattgag tcattttata
     2221 tctcgttaaa tgactcaatg tattgttatg tattttaaaa tataaattat ttaaaacgtt
     2281 ttttgtactt atatagaaat tcttctatat tttttgattg ttctcttatt tcaactgctt
     2341 ctatatctag taaataaagt atagaataat ttgtaagttc aacatattca ccatcttctg
     2401 aaccgagtgc atgtctctca atttttaatc ctttttcttc ataatatttt tttgtttcta
     2461 tatatagtga ttctcgcttt tgtatgtagt ctttcacttc attatttgga aagttatatg
     2521 aatccactaa tgtttcgcca tttataaaag ttttctcggt agcaactttt tcatcccaac
     2581 aatggatttc ttcccaagta aaaaatatct cagttccatc tggaatgaat gaaaacctgg
     2641 taataatata taaataatta ttgaaattta cttcataata ttcaggaata tcttcaaatt
     2701 ccatatagta atttgtataa ttaaaattac tattatcttt ttttacaaa
//
LOCUS       DAEOTL010000184         2743 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEOTL010000184 DAEOTL010000000
VERSION     DAEOTL010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.188"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            496..1317
                     /locus_tag="KRH82_003897"
     CDS             496..1317
                     /locus_tag="KRH82_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBG8657143.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDTDVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(1627..2406)
                     /locus_tag="KRH82_003898"
     CDS             complement(1627..2406)
                     /locus_tag="KRH82_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBG8657144.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         1013 a          374 c          324 g         1032 t
ORIGIN      
        1 ttataagatt atatactatc cttatactct agttaaatat attttaatca ctaatataaa
       61 ttagtttttt taacaaaaca ataaaagagt aaagtacaaa taattccttt gtgctctact
      121 ctttttaact ttctttagac aatgatataa tgataaatat aaaaaattat atattccatt
      181 ctatagaaat atgctcacca ataacatgta tgttgttaat caatatatta tatcaaatta
      241 tatcaaaatt acataaacct tataggacaa tcatatctta ttacaagaaa aatgtcttat
      301 ccatattgaa taagtcattc agttcatata caaagtcaat ttcattgaga aacatttaat
      361 atatgtttat aaaaatttca tactattctt tcatatttgc atgtgatata atttattaac
      421 tcataatttt gttaatcagt tgtgcttgta tattatttat ataatctaat attttaagaa
      481 ggtggtgtaa taactttgaa attaaaaatt gttggtagtg gcggtatgtc aattattcca
      541 agttcatttt gcaaatgcaa aatatgtgaa gaagccagac aaaaaggcgg aagatatgaa
      601 cgattagggc caagtttata tattgatgat ataaaaatgc tgatagacac acctgaagat
      661 attgcagtag cttgtaacag acaaaaaata tcggaagtaa aacatatttc aatttctcac
      721 catgacccag accatgttaa gggtattaga attgtcgaaa aaataggatg tgactttatc
      781 acaggagaaa ataatccaat tggcttttat gcgcttcctg aagtaattga agatataaac
      841 cgaacgaatc tcgattgtct taaatattat ggtgatgtta taaattgcat ttctattaat
      901 gaaacttcac atgtaaagat aaataatttt gatattgatt tgattaacaa taatccagac
      961 aggaatataa ccttctatgt tatcaaagag aatgaaaaaa aagtcatata tgcctgctgt
     1021 aatcccaagc catttactca tagtgatatg tactttgata ctgatgtttt aataataagt
     1081 ctagtttctg atgatggtat attaaatgat ggtacaaaac ttaaagacac accatttaaa
     1141 gatgaaatat ttactttaga tgagattgtt gaaattaaaa actattatag aattaaaaag
     1201 attatcatta cacatattga cgaaatgtgg ggaaaatcat atggttatta cagtgaatta
     1261 gaaaagaaac ttgataacat ttattttgca tatgatggta tggaaattat agtctaaatc
     1321 attaagtaat aagcataatg caaaataaga aaacttcaat ttaacagtat agttaaacta
     1381 tgtaatatca acatatctca gtttttacaa aatatcatag tatttatctt tataaaattt
     1441 caagtcctac atattttaat acttcaatat ctaaataaag taaaatcaaa aatatatttt
     1501 atatacatta tagacggctt atcggcacta gataagccgt tttgtcacaa ttattatttg
     1561 ctcaacaaaa cttctcataa tatataacag attgaatctc caactgatac ttaattaccg
     1621 aaactcttat tccttaatat gttgttgcat taaccaaacc ttcatcatca ttttttgtgg
     1681 caatagtttt gctaataaat gactggattt tgtatttata ccatacacag aaatatcctt
     1741 atttttcttt gcatccttca atgctttttt ggcaacaatg tctggagaca ctatacctgg
     1801 gaaatttttt gtcccttttt cagctacaac tatacctctc ttaaatagat ttgtactcat
     1861 ccaacctgga catacagcaa ttgcatttat ccctttactc ttaagttcaa catttaatgc
     1921 tcttgtataa tttcttataa acgctttagt tgaactataa atattttgat atggcaatgg
     1981 ctggaatgat gcttgtgaag aaatattcat gatatggctt cccttttgca tatatggaat
     2041 acatataagt cccaatgcta caacagcact aatatttaaa tcaatcatat taatagattc
     2101 atctatactt aaatcattgt atgaacagaa ttttgcaaaa ccagcattgt ttataaggta
     2161 ttttatacat acattttctt tacttaaaaa tgtaccaatt tcttttactt cttctatttt
     2221 tgataaatct tttgaaaaaa tttttacctt acttccaaat tcatctacta attgatttaa
     2281 tctcgccttg tttcttgcaa ctgcccatat ttctgttatt tcttcttcat ttattaataa
     2341 ctttagaaac tctttaccaa aaccactatt agcacccgtt ataattgcaa tcttcttata
     2401 actcataatt attctccttt accataagtt tatacgctca aactgtaaac ttatttttta
     2461 caaataaaac accctctatt cagatgttat attcatatta tttgagatat tatatttata
     2521 tcattttcaa taattgttat atagcataaa aaatagtgtt aatattatag aatcggtatt
     2581 gattatattt aaaaagtagt gttaattata ttatagaatc agtatttatt atattataaa
     2641 aagtagtgtt aatattatag aatcgatatt gattatattt aaaaagtagt gttaattata
     2701 ttgtagaatc agtattgatt atattgtaaa aagtagtatt aat
//
LOCUS       DAEOTL010000185         2725 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEOTL010000185 DAEOTL010000000
VERSION     DAEOTL010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2725
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.189"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            299..955
                     /gene="nth"
                     /locus_tag="KRH82_003899"
     CDS             299..955
                     /gene="nth"
                     /locus_tag="KRH82_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBG8657145.1"
                     /translation="MKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILS
                     AQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLC
                     ELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPN
                     PQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK
                     "
     gene            1149..1619
                     /gene="trmL"
                     /locus_tag="KRH82_003900"
     CDS             1149..1619
                     /gene="trmL"
                     /locus_tag="KRH82_003900"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBG8657146.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            1655..2503
                     /locus_tag="KRH82_003901"
     CDS             1655..2503
                     /locus_tag="KRH82_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBG8657147.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
BASE COUNT         1128 a          262 c          521 g          814 t
ORIGIN      
        1 aatggataag aaagatataa ttgagaagga agagataaat aaaaaaggaa tgaataagaa
       61 agatataatt gagaaggaag agataaatga aaaaggaata gataaaatga ttggtaaaaa
      121 agatgagata attgatgaga aagatataga gaattttatg gatattgaag aagataaaaa
      181 aagtatcaaa gtaagtaaaa aaagtactaa aaaaggtgaa acggagaaaa aaacaaagaa
      241 gagtagttct aataaggcta cacaaaaaac aagtaaagaa actaaaagta agtctaaaat
      301 taaaaatgag tcagcaaatg aaaaagacgt aaataagatt ttagacgagt tagaaaaatt
      361 gtatccagat gctaaatgtg agttaaatta tgggacagcc tttgaacttt taatagcaac
      421 tattttatca gcacaatgta ctgatgtaag agtgaataaa gttacttcag agttgtttaa
      481 aaagtacaac acagctagag actttgctaa tttgagcatt gaagaaatta gtaaagagat
      541 aaagagttgt ggtctttaca aaagcaagtc tcaaaaaata aaggatacat ctgaacagct
      601 atgtgaatta tatgatggtg aagtacctga tagcttagaa aagcttataa aattacctgg
      661 tgttggaaga aaaacagcag gggttgtact tagtaacgct tttaatcatc cagcaatagc
      721 tgtagatact catgtattta gagttagcaa tagaatagga atagtggacg agccaaatcc
      781 tcaaaaaaca gaatttgcac ttatggaagc tataccaaaa gaaagatggt cacactcaca
      841 tcatgtatta atttttcatg gaagaagaat gtgtaaagct agaaatccag aatgtgcaag
      901 ttgcccaata aaagaagatt gtaattatta taaagaactt aatgaaacga aataactttt
      961 agaaagtaag ttgtacaaga gggattttct gatataataa tacttgtgaa aatgttagat
     1021 aaaaaactat tatatacatg aaataaaaat tattattaac attattttat ataatagtat
     1081 aatattattg ttattctgtt tataaaataa aatttgataa ataaaagcga tacttaggga
     1141 ggattaaaat gtcattaaat atagtattag tagaaccaga aatacctcaa aatacaggaa
     1201 atataataag aacctgtgca gcaacaggtt caactttaca tttagtaaaa ccactgggtt
     1261 tttcattgga tgataaacac ctaaaaagat gtgggcttga ctattgggat atagctgata
     1321 tacaatatta cgatagcttt gaagaattac aagaaaagta tccaaatagt aaatactttt
     1381 tttctacaac aaaggctaaa cagtcacatt cagatgtgaa atatgaagaa aattgtttta
     1441 tagtatttgg gaaagaaaca aagggattac cagaaccttt gttgaaagca aatatggata
     1501 cttgtattag agtgcctatg ttggatgttg aaaaggctag gtcattaaat ttatcaaatt
     1561 cagttgctat tgtagtgtac gaggctttaa gacaaatagg atacccaaat atgaggtagt
     1621 ttcaacaagc ctaaatgaga aaggagcata cttaatgaaa aatctaaaga taatctgtga
     1681 cagtttatcg gacgtgccaa aagatttgtt agataaatat gatatagata tagtttcatt
     1741 aacagttata ctggaggaaa gagaatacaa ggatagaatt gatatatctg gagatgaatt
     1801 ttataaaagg cttagagaag aaaatgtata tccaaaaact tctcaagcta cttatgccca
     1861 atttaaggaa atttttgaga aatatacaaa tgaggataga gagatacttt atatagcagg
     1921 gtctgccaca gctacaggta cgtatcaaag tgctgtaatg gcaaagaatg atgtagatgg
     1981 taaaatatat acatatgact ctaacttgct ttgtatggga actggtttac ttgtaataaa
     2041 agcaggagaa cttgcaagtg aaggaaagtc tgttgctgaa atattgcctg ttttggatga
     2101 attaaaagag aaggcttttg ttatattttc agtagataca ttggaatatt tacaaaaggg
     2161 aggtagaata tcatctacta aggcagcaat aggaagtata ttaaatataa aaccgattct
     2221 tgaaataaga gatggattag tttcgcaaat atctcaagta agaggaaaga agaatgtaat
     2281 ttctaagatg atggaattga taaaatcaaa ttgtggtgat gatttatcag accaaattgt
     2341 gtatatagga tatagtgatg attttaagga aaaggaacaa ttatctaagg ttatgcaaga
     2401 tgaattaaga cctaaagaaa ttagattttt ccaaattggt gtgtgtatag gtgcacatgc
     2461 tggtcctggt gttactggta tcatatgctt aaaaaataaa taatatattt ttgggtgaca
     2521 ttatttattt ttttattaaa ttaggataga atattaatta ttgagatgtt aaattggatt
     2581 tattttgtat gaaattaagt gttgatatat tagatttagt ttgtagggaa gtgtgtaaat
     2641 agataagaat ctattgcaca cttttttata gtaagattta ttaaaaaaat ttcaaaatgt
     2701 acttgtaaat tgtatataaa aaaat
//
LOCUS       DAEOTL010000186         2626 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEOTL010000186 DAEOTL010000000
VERSION     DAEOTL010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2626
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.190"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..2063
                     /locus_tag="KRH82_003902"
     CDS             <1..2063
                     /locus_tag="KRH82_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8657148.1"
                     /translation="DDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQ
                     YGLYCITNFVWTISLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTIAGVTQNGFSS
                     TGFYVGFLLLIILVVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIK
                     KINEFSSDISTASLDLGTKIMLPNSDSKGKDSVDLIRDSLFSIQVEQPWLLLQFGNSN
                     AEEIGADRVEALVSASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLF
                     FNLGITIFVFLLTGMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIM
                     TRAGITLIVTVAFSISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAN
                     DSQSMGRRIFRRPYLYLAHRARRMERRLAGAVTAGGVAGAVAGSTISNRKATRNTATK
                     DSRGNTSSSMGQRVGSKVGAVLDTKNKVKDKASAVKENIKDMPTQTAYAVHSAKEKAK
                     SSVSDFKRGMVQEQQSRQSGRMEKREQHRQNIADKRMELQKAQEARQAQRKADGSATT
                     GATRPHERPATASTIPKPSAEKTQEVKRPATATTSKTNEPVKTTVIKERPLSSGTSDR
                     KTSQPTQPVHRQNVEKVVSQETRQNDTKDRRTKVQQTQSVQKNQQTTEKTRNLVMKKG
                     QKKK"
     gene            2060..>2626
                     /locus_tag="KRH82_003903"
     CDS             2060..>2626
                     /locus_tag="KRH82_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBG8657149.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYAREYGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGMDDLNVAIQSYNYGGGYVGYVAGKGNKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRY"
BASE COUNT          793 a          544 c          658 g          631 t
ORIGIN      
        1 tggacgatac cataaatgca gaaaatcttt actcaaaata tccgctgtcg aattaccagc
       61 ttgattttta tgtggataat agctggtcgt ggcttccgtg gaactggctg gacggtatcg
      121 gaaaatcggt gcagtatggg ctttactgca ttaccaactt tgtctggacg ataagccttt
      181 atttaagcaa tgccacgggc tatgtggtgc aggaagccta taaactggac ttcattaacg
      241 atatggcaga cagtatcgga aaaagcatac agaccattgc aggcgtaaca cagaacggtt
      301 tttcttctac gggcttctat gttggtttcc tgcttctcat tatcttagtg gtgggacttt
      361 atgttgccta tacgggactg ataaaacggg aaaccagcaa ggcacttcat gccgttatta
      421 actttgtggt ggtgttcgtg ctgtccgctt cgtttattgc ctacgctccc gactacatca
      481 aaaagataaa tgaattttca agtgatatta gtaccgcttc gttggacttg ggaacaaaaa
      541 tcatgctccc aaactctgac agcaagggca aggacagcgt ggacttgata agggacagcc
      601 tattttctat tcaagtggaa cagccgtggt tactcttaca attcgggaac agcaacgcag
      661 aagaaatcgg ggcagaccgt gtagaagctc tggtatcggc aagcccagag gacgaggacg
      721 gaaagaccag agaggaagtc gtgaaaacag aaatcgagga caacgacaac aacaatctga
      781 cgataccgca ggtcgtgaac cgtttaggta tggtgttctt cctactgttc ttcaacttag
      841 ggataacgat atttgtattc ttgcttacgg gcatgatgtt attcagccag atacttttta
      901 ttatctttgc tatgtttctg cctatcagct ttttactttc catgataccg agctatgaaa
      961 gcatggcaaa gcaggcaatc gtgagggtgt ttaataccat aatgacacga gcaggaataa
     1021 cgctcattgt aacggtggcg ttcagcattt ccagtatgtt ttataacata tccacggact
     1081 atccgttttt catggtggcg ttcttacaga tagtgtgttt cgctggtatc tacatgaagc
     1141 tgggtgactt aatgagtatg ttctctttga acgctaatga tagtcaaagc atgggacgaa
     1201 gaattttccg cagaccatat ctatacttgg cacatagggc tagacgtatg gaaagacggc
     1261 ttgctggtgc ggttactgct ggtggtgttg ctggtgcggt ggctggtagc acgatttcaa
     1321 acagaaaagc gacaaggaac acagctacaa aagatagtcg gggtaataca tcttccagca
     1381 tgggacagcg tgtaggttca aaggtgggtg ctgtcttaga tacaaaaaat aaagtgaaag
     1441 ataaggcaag tgctgtcaaa gagaatatca aggatatgcc gacacagacc gcttatgccg
     1501 tccactccgc aaaggaaaag gcaaagtcca gcgtgtccga cttcaagcgt ggcatggtgc
     1561 aggaacagca gtccagacag tcgggacgta tggaaaaacg ggaacagcat aggcagaata
     1621 tcgccgataa gcgtatggag cttcaaaagg cacaagaagc aaggcaggca cagcgaaagg
     1681 ctgacggatc agcgacaacg ggagctaccc gtccccatga gcgaccagcc acagcttcaa
     1741 ccattccaaa gccgagtgct gaaaaaacgc aggaagtcaa acgccctgcc acagcgacga
     1801 cttcaaaaac aaatgagcca gtcaagacaa cggttatcaa agagcgtccc ttatcttcgg
     1861 gtacttctga taggaaaacg agccagccta cacagccagt acataggcag aatgtagaaa
     1921 aagtggtatc gcaggaaaca cgccagaatg acaccaaaga ccgcaggaca aaagttcagc
     1981 agacgcaaag cgtccagaaa aaccagcaga ccacagagaa aacccgtaac cttgtaatga
     2041 agaaaggaca gaagaaaaaa tgaaactgaa acatattgct attatcggca gtctgtttcc
     2101 tatcctcttt tcactggtgc ttttctttgg ggtgttgatt agtgcggaca gcgacgacga
     2161 gaacagcaac ttttcttctg gcattacggg tatgaactta tccgcagaag tcttgaaaca
     2221 tcagcctatg gtggaaaagt acgccagaga atacggcatt tccgagtatg tcaatgtgtt
     2281 gctggcaatc atacaagtgg aaagtggcgg tacagccgag gacgttatgc aaagctctga
     2341 aagtctggga ctaccgccca attcattaga tacagaaagt tcaatcaagc aggggtgtaa
     2401 atattttgcg tccctgcttt cgtcctgcaa aaatcaaggt atggacgatt tgaatgtagc
     2461 gatacagtct tataactatg gcggtggtta tgtgggatat gtggcaggaa aaggaaataa
     2521 acacactttc aaccttgcag agagctttgc ccgtgaaaaa tcgggtggaa agaaagtaac
     2581 atacaccaat ccaatagctg ttgcgaagaa tggaggctgg cggtat
//
LOCUS       DAEOTL010000187         2574 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEOTL010000187 DAEOTL010000000
VERSION     DAEOTL010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.191"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(226..1476)
                     /locus_tag="KRH82_003904"
     CDS             complement(226..1476)
                     /locus_tag="KRH82_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBG8657150.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRMIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1508..2449)
                     /locus_tag="KRH82_003905"
     CDS             complement(1508..2449)
                     /locus_tag="KRH82_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBG8657151.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          775 a          493 c          239 g         1067 t
ORIGIN      
        1 aatacacatt taaaacctta taaatataca aatacaatta tatgaatttt catcctcaat
       61 tatagcatag aatatgacta tctatatcct aaaattatcc atttctaaaa aaaaggtaac
      121 tattattaag aatatcaact tatagaattt atattccaca tacgattttc aatcaaaaaa
      181 acaagggcta aaaagtgaat tgtgcacttt ttagcccttt attaattatt catttatttc
      241 atgtaagaat agaccacatc ttactttagg ttcaaaccat gttgacttag ctggcattat
      301 cttatttgca tctgctactc ttattaaatc ttcaatacta gtaggataca ttgcaaatgc
      361 tactttcata tcttcattaa ctcttttttc taattcttca agacctctaa ttccaccgat
      421 aaaatcaatt cttttatcta ctctaggatt atcaattcct aaaatagcat caataacata
      481 gtcttgtaat atagaaatgt ctaatgaatc aacagggtct tctatttcta ataaattttt
      541 atttgctttc attttatacc acttatcacc taggtacatt ccgaaagttc cttttttgtc
      601 aggtttatat ttttcttttc cttctatttc ttctagttca aaattttctt ttattttatt
      661 tataaattct tcctcgctta aaccatttaa gtctttgata accctattat aatccaaaac
      721 cattaaattc tcatctggtg caatcattgc tatgaagtaa ttaaattctt cttttccagt
      781 ataatttgga tttttagctc tcatttcttt ggctacattt tctgctgaag ctgtcctatg
      841 atgaccatct gcaatgtata gataatctaa tttttcaaat ttatctacta ggttatctat
      901 tatatcatca ttatcaatct tccatactgt atgctctatc ttgtcatctg ttatgaaatc
      961 atataaaggt tcattattat ccataaaatc attgattata tcatctatca tcctttgatg
     1021 tttgtaagtt acaagtatag ttcccgtatt agcatcacag tattttatgt gtttagttct
     1081 atcaatttcc ttttctggtc gagtgtactc atgttttttt attgttccat tcaagctttc
     1141 atcaactgat atacatgcta ctataccaac ttgagctcta ccatccatga tttgtttata
     1201 tatatatata cactctttgt catcttttac tagaatttct tgttttcgaa actcatctaa
     1261 attttctcgc gcttttaaat aaactttttc atcatataaa tctatatttt catctaaatc
     1321 aatttctgat ttatctatat gcaaaaatga atatggattc ccttctgcaa ttcttctagc
     1381 ttctttacta ttcataacat cgtaaggaag tgctgctact ttatctacta tatatttatt
     1441 tggtctaatc gccttaaatg gtttaatcgt tgccattact aatttcctcc taattataca
     1501 aaatatttta taatgctacc cctattagat tgttgaagtc aagaaagaaa tcttgaatca
     1561 catttactat ttcgtctcct attctttctt gagcttctac tgtagatgcc ccaatatgag
     1621 gtgtaggaga aactcttgga tgatttacta agtctaaatt taatgtaggt tcttgttcat
     1681 aaacatctat agcagctgct gataatttac cttcatctaa tgcttttagt aaatcttttt
     1741 catcaactaa accgcctctt gcacagttta ttaaataagc ccctttcttc atcttattta
     1801 tttctttttc agttattact gcccccttat tcttatcaaa tggtatgtgt aaagataaga
     1861 aatctgcatt ttctaaaact tcttccatat cacagaattt ataattgtta aagccttgcg
     1921 cctcacccat tatgtcagta tatataacat tcatacctaa taattctgct ctctttgcaa
     1981 cttcttttgc aattcttcca aaacctataa gtccaagtgt ctttccatta atttctgtac
     2041 ctttatactt tttcttctcc cattttccat ctctcatagt tacatttgca gtatttatga
     2101 atcttgcaag aacaaataat tgacctattg taagttctgc aacagatata ctgcttgcat
     2161 ttggagtatt cataactttt atgccattag cttgagcata tttaacatct atattatcca
     2221 gacctactcc acctcttact atcaacttca actttttacc ctctaatgct ttatctatta
     2281 catctttagt aactttagta gctgaacgta ctacaagtac atcaacatct ttaagtttat
     2341 ctcctaaaac atctttttca taaaactgct ctatcacatt aaaatctaac tctctcaatt
     2401 ttctcgctgc ttctttctct attccatcag taactaatat attatacata acaaactcct
     2461 ccaattttta ttcacttaat ttttccaatt tttatttttt aaagtatttt catcaataaa
     2521 aaactttact taattcaact ttctgtttat ataattttca aaatattttt ttat
//
LOCUS       DAEOTL010000188         2528 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEOTL010000188 DAEOTL010000000
VERSION     DAEOTL010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2528
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.192"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            121..855
                     /locus_tag="KRH82_003906"
     CDS             121..855
                     /locus_tag="KRH82_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBG8657152.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(998..1489)
                     /locus_tag="KRH82_003907"
     CDS             complement(998..1489)
                     /locus_tag="KRH82_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBG8657153.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            1838..2221
                     /locus_tag="KRH82_003908"
     CDS             1838..2221
                     /locus_tag="KRH82_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657154.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKEYLYV
                     SSMYAIKEAKLESRVNSGRVKQYNG"
BASE COUNT          986 a          277 c          366 g          899 t
ORIGIN      
        1 atattattaa aaaatttatt tatagaaact tttattattt tatataaaag tgataaaaac
       61 ttatattttg tgtttagtag agtgttgcta agtgaatata tttaaaatgg aggaaacttt
      121 atgaaacaaa ataaatatga tgatgataga ttttttaata aatacagtaa aatggaacgt
      181 tctacaaatg gattagcagg tgctggagag tggcatgttt taaaaaaaat gttacctgat
      241 ttcaaaggaa aaagagtttt agatttagga tgtggatttg gatggcattg tcaatatgca
      301 gttgagaatg gagcaatttc tgctgttgga gttgatattt cagagaaaat gttaaaagaa
      361 gctagaaaca aaacgcaact tgataatata aattacatat gtatgcctat tgaagatatt
      421 aattttccaa aagatagttt tgatgtagtt attagttcct tggcatttca ttatattcaa
      481 tcatttgaag atatatgtaa gaatataagt aattgtcttt caaataaagg taattttgta
      541 ttttctgttg aacatcctat atttactgca tatggaagtc aagagtggta ctgtgataaa
      601 gatggcacta atctacactg gccagtagat agatattttg aagaaggagt acgtaagtca
      661 aattttctag gagaagaggt tataaaatat cataaaacat taacaactta tttaaatacg
      721 ttaatgaaaa caggatttga aatattagaa attattgaac ctcaaccaga agaaaaactg
      781 ttagatacaa ttcctgatat gaaagatgag ctacgtagac ctatgatgtt acttgtatct
      841 gcaaaaaaaa gataagtaaa tataaataat cattattgta gaaaaaaagt tgtagaaaat
      901 aattatacta atggagatga ttataccagt ggtattaatt acaccagtag taaggaggca
      961 aaagcattcg ttgcttttgc cattttttaa gttgcaatta tacttctacg tagtatattt
     1021 cgtttccatt ttcttctata agctttttca tatcttcaaa ttttaaaaat acagtagcag
     1081 tattatcatt tggatgtata cctattttat ccatttttaa taaatcctta tcaaatacaa
     1141 cttttacaac agcctcttta tcatttaata taccaaaagg agtcacagct cctttagtaa
     1201 gtttcaagta tttttgaagt ctttcttctg atgcaaaact aagaggttta ctatcaattt
     1261 gttgacgaat atcttttaaa tctgcttttt tgtctttacc taatacaact aaaaaatgtt
     1321 cttttccttt agcatcacga agaaataggt tttttacaac aaattccata tgtaatgttt
     1381 ttaattcttc catttcttca attgtataaa ctggtggatg atttacagcc tcataaggta
     1441 tgcttaactc atctaatttt ttatatactt cctgttgttg attgttcatg atttcctccc
     1501 attagaaatt tattttatat ataaataata ttatcacaga aaactttaaa agaaaacgtt
     1561 ttatataata tagacaatag attatatttt tataaagaag caagaatact caataaaact
     1621 taaagaaatt aaacaatttc taaaaatacc ttgaaaatag aaccttattt gccatttata
     1681 aattatataa aaagggatta tataaagtca tatatgaaaa aactatatta tactatcttt
     1741 tctttttgga ataaactata ctttaaatat agatatttaa tttaaataaa ttttacagta
     1801 ttaatagtaa attatcttag aaaggaatgt gctttatatg tctacagaca aagttgttgg
     1861 aatcatagat gaagaaacgg cagaacttgc aggaattgaa tatactggta aaatttatgc
     1921 ttcttctggt gttataaaac atataaagaa aaaacataga tgtcaactga gtaaagatat
     1981 ttttaatgat ataatagaca ctataaaaat ggtattaaag tcacctgaat atataggaag
     2041 tcatcctaaa aaacctggaa aaagtgtgga gtttataaaa aaaattgatg attatatttt
     2101 agtagctaca gaattagata caaaaaaaga atatttatat gtatcttcaa tgtatgctat
     2161 aaaagaagca aaattagaaa gtagagtaaa cagtggaaga gtaaaacaat ataatggtta
     2221 acataatatt attaattttc cctaaaatat tgaaaaatat tattatataa gttataatat
     2281 taatatacac gtagatattt attagttaga tttgaggttg gaaaaggcac ccaatacgct
     2341 actatagagt agttaataga gatgcaggat acgccgccct gccaaatcta attaaattaa
     2401 aaagagagga ttaattcctc tcttattgtt tttttgagat actaatttaa tctatataga
     2461 aagattgaag gtcatttata ctaaaagttt tcagttatat acattaaact aattaaataa
     2521 gatattta
//
LOCUS       DAEOTL010000189         2484 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEOTL010000189 DAEOTL010000000
VERSION     DAEOTL010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2484
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.194"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            160..606
                     /locus_tag="KRH82_003909"
     CDS             160..606
                     /locus_tag="KRH82_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBG8657155.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            608..1702
                     /locus_tag="KRH82_003910"
     CDS             608..1702
                     /locus_tag="KRH82_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBG8657156.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMTKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLLSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            1790..2320
                     /locus_tag="KRH82_003911"
     CDS             1790..2320
                     /locus_tag="KRH82_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBG8657157.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
BASE COUNT         1033 a          239 c          428 g          784 t
ORIGIN      
        1 ccaatttcta attttatcat gattatttta tataatagtt ttttaaagaa ttaataaaac
       61 atagatttag agaataaaat attcttgact atattaattg tttaatataa tatagttgat
      121 atagtcaaac atattataat tatagaaggg aaatttaaga tggattttaa aaatttacag
      181 tatgaaagtt tgtcatatat tatttgtaac ttgcaaaaaa actttaaact ttattgtgaa
      241 aaatgtttaa aaccatataa acttacgaat ggtctatatt tctatttaat ttatattaat
      301 aaaaatagga attgttcttt aaatgatgtt tctacagaat ttgaagttga taaagctcat
      361 acaacaagaa ctatatctag gttagaacaa gatggataca tagaaaaaat ccaaaaccct
      421 aatgatagta gagcttttca gttgagagta acagataagg gtgaggaagt attaggggat
      481 ataaaaaaca tattttcaaa gtgggataat cacataaaaa aagagttctc ggatacagaa
      541 tataaagaac tggtaaagaa tttacatgtg gtaaaggata taaaaacagc tgtggaggaa
      601 gaataggatg tattgtaatt tattaaaacc aattaaaatt ggaaatttgg aattaaaaaa
      661 tagagtatct tttgcaccta caagcatggg tcttaaattg gaagaaaaaa ttaaaaagtt
      721 ttctgatatt gctaagtcag gagtagctct gattactcta ggagatgtat ctattagacc
      781 tagttttcat aaggtagcta taagcctatc ggatgaagat ggagtcatga aatacaagaa
      841 aattgtagat gaaatacaca attctggtgc aaaggtatca gcacaactat tttgttcaga
      901 ttatgatgtt aatttaatta aagatactat gaagatggga attacttcac atgatgagat
      961 aaaaaaaata atgaatgacg gagtaaaaga ttacataaca aatatgacca aagaagaaat
     1021 taaaaatatt ataaatttat ttaaagtaac agcattgaat gcaaaaaaag caggttttga
     1081 catgattcaa attcatggtg ataggcttgt aggaagtttt tcatcaagta tatttaataa
     1141 tagaaatgat gaatatggtg gaacgtgtga taatagaagt agatttgcaa gcgaaataat
     1201 tagtagtatc cgagatgaag ttaaggacat tccaatagac tataaatttg caataagaca
     1261 agaaaatcct cattatggaa atgcaggagt tttactttcg gaagttgagt attttgttaa
     1321 aaaatttgaa tccctaggtg taaacagttt tcatgtaaca cttgcaaatc attcaaaatt
     1381 agaagatact ataccaacca ataatcatcc ttactttaaa gatgaaggct gttttttata
     1441 tttagctgat gaggtaaaga aacacacaaa tcttccagta tgtggggttg gaaaattgtc
     1501 tagcccagat tttatagaaa gtattatttc aaataataga gtagatatgg tttctatgtc
     1561 aagacaatta ctagcagata gtaattggtt acagaaagta aaagatggaa gagtagatga
     1621 gattaaaaag tgctgttatt gtaataagaa gtgtgcagat gctttacaaa cacgctctca
     1681 gtttggatgt atactagatt agaatatcct tataaaaata aataatttgt taaggttaat
     1741 atatttttgg tgatttagat aagtatttag ataaagagga ggagacatca tgaaaagttt
     1801 agttttatat tcaagtttaa ctggaaatac taaaaagatt gcttatacta tatatgatga
     1861 aattcaagaa gaaaaagaca ttaaagatgt aaatgaatta gttgattata gtattgacta
     1921 tgaaaattat gatatagtat tcttaggcta ttgggtggac aagggaattt gtgataaaaa
     1981 ttcaaaacaa gtgcttgaaa atattcacaa taaaaagata gcactatttg gaacaatggg
     2041 agcaagtaaa aaaggaagtt atggagctag tataatagaa aagatagaat caattatccc
     2101 aaaagataat gaaatattag gttcattcat atgtcaaggt aagatagcag aaggattgaa
     2161 agcaaaatat aaagagatgc taaaactttc tcctgacaac gaacatattc gccaacaatt
     2221 aaataaccat gaggaatctc aaagtcatcc agatgaacaa gaaatatatg aagccagtat
     2281 gtttgcaaaa aatatgatga ttaaagctag tattgtgtag tagttaaaca ataagttcat
     2341 ataagatata gaataaataa tttagtaaaa aagtatagca aataatttgc tatgcttttt
     2401 ttatgaaatc aaaaaaataa taaaaatact tgactgtaaa ccttgtttat acattatttt
     2461 atagaaaata agatagtttt aaat
//
LOCUS       DAEOTL010000190         2450 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEOTL010000190 DAEOTL010000000
VERSION     DAEOTL010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2450
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.195"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..2218
                     /locus_tag="KRH82_003912"
     CDS             <1..2218
                     /locus_tag="KRH82_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBG8657158.1"
                     /translation="VYSLKVEAGTTATLNVSDTPKVTDTLIELFKIDMETQKDNPQGN
                     ASLAGAEFTWKYYAGFYNKDNLPAEATRTWVTKTIAETDGDGTTHYITKLADAYKVSG
                     DSFYMQDGKAVLPLGTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDL
                     AVLSGSNQFSVSDKVIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNENAVLVE
                     GKLYKKNEVVKTIRTDIEGITSTSADLLPYGKFRIVESEAPNGYLTDGAKPIDFTITE
                     NGKIVDLTDEAHSIYNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHVVVTDD
                     NGQFSTSADWASHKHNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMRCDSNKG
                     FELIPPFEIVVSRNNLVVDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTV
                     KLDGLTKGTKYQLKGWQMLKEENTELIIDGKRVENDYTFVADDEEMKVEISYTFNASA
                     LGGKNLVTFEELYDFSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKE
                     LEAGKDVTFIDTVTLEGLEVGTQYKLVGWQMLREENAELLINGKRVESDYTFIADSET
                     MKVEVAFTFDATSLDGKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEE
                     PEKPETPPTPEKPNRPSDSPKTGDNTNLYGLLALLLTSGAGLAGIFFYKRRKMKKS"
BASE COUNT          826 a          487 c          557 g          580 t
ORIGIN      
        1 tgtatattcc ttaaaggttg aagctggaac gacagcaacc ttgaatgtat ctgatacgcc
       61 gaaagtaacg gacactttga ttgaactttt caagattgat atggaaacac agaaagacaa
      121 tccgcagggg aacgcttctc tagcaggtgc ggaatttaca tggaagtatt atgcaggctt
      181 ctataacaaa gacaatctcc ctgccgaagc tactcgtaca tgggttacaa agacaatcgc
      241 tgaaacagac ggcgacggga caacccatta tattacaaaa ttagcggacg cttacaaggt
      301 atctggcgac agcttctata tgcaggacgg caaggcggtt cttccacttg gaacgctaac
      361 cgttgaagaa acaaaagctc caaacggcta cttgttagac ggtgcatata tgcaggctgg
      421 cgataagtcc gaacagatta agggcttata tgtaacacag attaccgagg acggcgacct
      481 tgccgtatta tctggaagta accagttttc cgtatcagac aaggttatcc gtggcggtgt
      541 caaaattcag aaacgagatt tagaaacggg cgatacaaag ccacaaggaa gtgccacttt
      601 gaaagataca gcttttgaca tcatttcctt aaatgaaaat gcggtattgg ttgagggtaa
      661 gctctataag aaaaatgaag tggtaaagac aattcgtaca gatattgagg gtatcacttc
      721 tacttctgct gaccttttac cttatggaaa attccgtatc gttgaaagtg aagctcccaa
      781 cggttactta actgacggtg caaaaccgat tgattttaca atcacagaaa atggaaaaat
      841 cgtggactta acagacgaag cccattctat ctataatcag attaagcgtg gagatattga
      901 gggtgtaaaa atcggtgcag gcacacacaa gcgtcttgct gatgttccct ttaggatcac
      961 aagcaagacg acgggcgaaa atcatgttgt ggtaactgat gataacgggc agttttccac
     1021 ttctgctgac tgggcttcac ataagcacaa tacaaacgca ggaaagacca gcgaggacgg
     1081 tgtgtggttt ggaacttctg aaccagacga cagcaagggt gcgttgcctt atgataccta
     1141 catcattgaa gaaatgcgtt gcgacagtaa caaaggtttt gaacttatcc caccttttga
     1201 aatcgtggta tcaagaaata accttgtggt tgatttagga acgctgactg atgaatacga
     1261 aaaagaaatc tctatccata ccacagcaac cagcaaagac ggcgaaaaaa ctatccttgc
     1321 aggaaaagag gtaacaatcg ttgatactgt caaattagac ggacttacaa aaggcacaaa
     1381 gtatcagctc aaaggctggc agatgttaaa agaagaaaat acagagctta tcattgacgg
     1441 gaaacgtgta gaaaacgatt atacttttgt cgctgatgat gaagaaatga aagtggaaat
     1501 ttcctataca ttcaatgcgt ctgctttagg tggcaaaaac cttgttacct ttgaagaatt
     1561 gtatgatttc agcaatccag acgaacccgt gaaagttgcg gaacataaag acattgagga
     1621 cgacgggcag accgttttaa ttacagaacg tatcatcaag atacatacga ctgctacgga
     1681 taaggacggc aacaaagagc ttgaagctgg aaaagacgtt acattcattg ataccgtaac
     1741 cttagagggc ttggaagtcg gtacacagta caaacttgtg ggctggcaga tgttaaggga
     1801 agaaaatgca gagcttctta tcaatggaaa acgtgtggaa agtgattata cgtttatcgc
     1861 tgacagcgaa actatgaaag tggaagttgc ctttaccttt gacgctactt ctcttgacgg
     1921 caaacagctt gtaacttttg aagaattgta cgatttgagc aatccagacg aaccgaagaa
     1981 agttaccgaa cataaggata ttgaggataa gggacagaca attaccttta aggaaaagcc
     2041 agaagaacca gagaaacccg aaacaccacc gacaccagaa aagcctaaca gaccgagcga
     2101 cagtcccaaa acgggcgata acacaaacct ttacggactg cttgcacttc ttttgacctc
     2161 tggtgctgga ctggcaggta tcttcttcta caaacgccgt aaaatgaaaa aatcataagg
     2221 cggtaacggt atgagaaaag aaaaatcacg ctctccgccg aagctgtcaa acggcagact
     2281 tccgcttatt ctggcttgtc tgccaacaac ctgcaagaac acggatagtc aagggtgcgt
     2341 aagcattgat tttacccttt actatctgtg ggattgctgg tacttcccaa accgccagaa
     2401 taagaaatca caatcaattt attaaaaata gaaagaaacg aggtaaaaca
//
LOCUS       DAEOTL010000191         2417 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEOTL010000191 DAEOTL010000000
VERSION     DAEOTL010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.196"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(798..1835)
                     /locus_tag="KRH82_003913"
     CDS             complement(798..1835)
                     /locus_tag="KRH82_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBG8657159.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNSTKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVFEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
     gene            complement(1932..>2417)
                     /locus_tag="KRH82_003914"
     CDS             complement(1932..>2417)
                     /locus_tag="KRH82_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8657160.1"
                     /translation="LGTCPSMTVRENLSLALNKGKLLNLKKCLRHKTNDLEHLLEGIS
                     LDLKKYLDIKVQYLSGGQRQSLSLIMSSLASPKVLLLDEHTAALDPKTSNEVIELTDK
                     IVREKNITTLMVTHNLKHALQYGDRLIMLHKGEVVLDVKDKEKEDLTVEEILEKFEYA
                     V"
BASE COUNT          799 a          358 c          308 g          952 t
ORIGIN      
        1 cctttgaaaa tatttttata attttaatta tttgctaatt ttgtgtataa aaaaaccaca
       61 tagtgtacaa aactatgtgg taaaaacacg aataagccac atagtttaat ctatgtggct
      121 cttatatagt taaatgaaaa ctttataaac aatatagcca acatagatac aatcccaaaa
      181 ttttagtagt cttaaggggt ctgtatctat gttaaaacgt aggtacaaac cctaaaaata
      241 gtggctataa taataataat attttctatt gtttaataaa gtattcataa ttatctctcc
      301 cttttaatat tttaattagt cagaaaatta tatgtattct cgacttgtta taaattataa
      361 attatacaat aataaaagtc aactgctaaa tttaattaaa atactaaata atgtatactc
      421 agaatacttt taaattaatg tattgtttgc aaaaaaacgt tatcctaagt tataagtgaa
      481 tgtggaaatt ttatcaaaat atttactaaa tatggaataa ctagacatgt atatcaatca
      541 aatatcataa aaaaaagctg tctggagaat attaaaattc ttttggacag ctcaagtagt
      601 gattagaaag ttatataact ttcataatca gtcgtcaata tagacgactt ttatggaaaa
      661 tgaataactt tatatgcaat attcaaattg ctacaataag cacaattttc aaagggttag
      721 ggtggataag agtacttatt atataaagtt ttcatattac ctacttcata ttacctattt
      781 tttgaaatta ataggtttta ttttgcagat tttgcatttt catctgactt tatatacttt
      841 atattatctg ctgataactt ttgcatgtca agtgctttta gtgtatcttc gttaattatt
      901 atttcagttt catctaatgt agtaactggt atatcgccaa cagattttcc ttctaatact
      961 tcaatagcaa gttctccagc cttataacct agtttttcat aatctattcc acaacaagct
     1021 aaagcaccag aagatacaga accttcttca gaggctatta taggaatctt gttttcatta
     1081 gcaactttag aaactattgg catagaagaa actattaaat tgtcagtagg gacatataaa
     1141 acatctattt tgccaactaa actagaaata gcttggttaa cttcacttga agagctgatt
     1201 cctttttcaa atacttcata attatttttc ttagcataat catgtagaga atcaacttgg
     1261 atttttgaat taacttcact agtattgtat ataaccccta ttttctttgc ttttggagtc
     1321 aatgttttaa ccaattctaa tgttttatca attgaaagat aatcagatgt accagaaaca
     1381 tttccacctg gtttttcaag agatttaaca agtccagctt ctacagggtc tgtaacagca
     1441 gtcattatta tcggaatatc tttagtagaa ttataagctg cttgtgcaga tggagtagat
     1501 atagcatata tcaaatcttt tttgtcggat acaaacttac tagcaatact ttgtgtagta
     1561 ggcatatcat tttgtgcatt ttggaaatct atttttatat tatctccatc tttatagcct
     1621 ttatcttcga gtgctttgat gaatcctttc tttgctttat ccagagatgg atgttccact
     1681 aattgactaa tacctatatt tttttgtttt ttgctatctg tttctttatt ttcatttgaa
     1741 gcattggagc catcattttg agaacatcca gtaagcattg atacaccaag tactcctgct
     1801 ataattaaac ttaatatttt tttacttttt atcattttat tttcctccct taaaatttat
     1861 taattatatt tgttcatata ttcatatgat agattataaa tatttctgat taaaactaag
     1921 attttaattt cttatactgc atattcaaat ttttctaaga tttcttcaac tgttaaatct
     1981 tctttttctt tatcttttac atctaataca acttcaccct tatgaagcat tatcaaccta
     2041 tctccatatt gaagagcgtg tttcaagttg tgagtaacca taagtgtagt tatatttttt
     2101 tctcttacga ttttatctgt taactctatt acttcatttg atgtttttgg gtcaagtgct
     2161 gctgtatgtt cgtctagtaa taagacctta ggacttgcta agctagacat aattagtgat
     2221 agtgattgtc tttgacctcc tgaaagatat tgtactttaa tatctaaata tttttttaaa
     2281 tccaaagaaa ttccttcaag taagtgttcc aagtcattcg ttttatgacg aagacatttt
     2341 tttaagttca ataatttccc tttattaagt gctagagata aattttctct aaccgtcata
     2401 gaaggacaag ttccaag
//
LOCUS       DAEOTL010000192         2344 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEOTL010000192 DAEOTL010000000
VERSION     DAEOTL010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2344
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.197"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            206..322
                     /locus_tag="KRH82_003915"
     CDS             206..322
                     /locus_tag="KRH82_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein"
                     /protein_id="HBG8657161.1"
                     /translation="MDDDINMIAIRPEDIRVEFNRDFKEIIDLKLRPYRYKN"
     gene            486..1553
                     /locus_tag="KRH82_003916"
     CDS             486..1553
                     /locus_tag="KRH82_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBG8657162.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEAAKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            1745..2275
                     /gene="rnmV"
                     /locus_tag="KRH82_003917"
     CDS             1745..2275
                     /gene="rnmV"
                     /locus_tag="KRH82_003917"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBG8657163.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRYEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
BASE COUNT          988 a          240 c          450 g          666 t
ORIGIN      
        1 aataaaatat tgagcgatta ttaaaaagat atatatatat aatttaattt gagcagtttg
       61 ttatatatta taaaaaagag aaaaataaaa ggtaaattgt ttctggataa cttaaaattg
      121 gaagtaagaa tatttaacta gagaagaatt atttaagctc aggttagctc taggagtagc
      181 tgattttata ggagcaatag attttatgga tgatgatata aacatgatag caattagacc
      241 agaagatata agggtagaat ttaatagaga tttcaaagaa attatagacc tcaaactcag
      301 accgtatcga tataaaaact aaagctagat gatatagtgt tgtatatagg accatcagct
      361 gttatggcag tattagtgct tttaacaaat ataatagtaa aacttttgta tgaattgata
      421 ataaaaaaat taaaaaccaa gacataaaaa tggcaacaaa aagaagttga ataagggagg
      481 taaaaatgaa atttaagaag ttagtctctt tgggaatatt atcaacactt ttattgagtg
      541 taataactgg atgtagtaat gtttcatcag gttcaaactt aaagtctaat aataagacaa
      601 aaggagagtt aacagtttat acagcaattg aggaagatag tatagataca tacttagcta
      661 catttaaaga gaaatatcca gatattaaat tgaatgtact tagattatca gtaggaggta
      721 taacagcaag attattagca gaaaaagata atcctaaagc agatgtgtta tggggtgttg
      781 cagctacaag tttgataatt ttagatgaca aagaaatgct agagccatac gctccgaaag
      841 gctttgataa ggtaaatcct gcatttaaag atgataagaa agttccttct tgggttggaa
      901 tagatgcttg gatgactggt ataacagtaa atactaaaga attaaaagct aaaaatatat
      961 cagctcctag ttcttatgaa gatttaataa agccagaata taaagatctt atatctatgc
     1021 ctagtccagc ttcttcagga acaggatatt taacagtatc agaactcata caaattatgg
     1081 gtgaagaaaa agcatggcag tacatggata aattacataa aaatattggt gtatacactc
     1141 agtctggttc agcgccagct atattagcag cttcaggaga atatcccatt ggtatatctt
     1201 ttggaaatag aggtataaag ttaaaaggtg aaggttatcc agtagaagta gtatttccaa
     1261 aagaaggttc tggatgggag atagaatcaa atgcacttgt gaaaaaagat aatataaaag
     1321 aagcagcaaa agtattttta gattgggcta taagtaaaga tgcaatgaat gagtattcta
     1381 agaattttgc agttactaca attgacacgg gaaatccggt gccagaagga tttccaaaga
     1441 atccattaga acagatgata gataatgatt taaaatcagc agcaagaaat agagaggcta
     1501 tactaaataa atggatagaa aaatatgatg gaaagacaga aaaagagagc taagccttac
     1561 aataaaattt agtacaaaaa gcgcctagaa tataagtttt atatctaggc tcttttgata
     1621 tatttattta aaatgcatat ttctatataa aaataaatag tttagtacct tgattaaatt
     1681 aaataaaaac cttaaaataa agagatgtaa agaaaaacta aaaacgaata aaaggtgaat
     1741 ttatatgata aaagaaataa tagtagtaga gggtagagat gacgttacag cagttaagag
     1801 agcaatagat gcagaactta taactacagg tggatttgga tttccaaaag gtgtaatgga
     1861 gcgtataaaa gctgctaatg aaagacgtgg tgttataata tttacagacc cagattttgc
     1921 aggtgaaaaa ataagaaaaa aaatagcatc agaagttcca ggatgtaaac atgcatttct
     1981 accgagagag gaagctaaaa aggatggaga tataggtatt gagaatgcta ctcctcaaag
     2041 tataatagca gctctgaata aagttagaac tgaaaataca gaaaaaagat atgaatttaa
     2101 gcaagttgac ttaattagaa atggtcttat aggtaatgaa gaagcatcac ttagaagaga
     2161 tgcacttgga aaaatacttg gaattggata tggaaatgca aaacaatttt taaatagatt
     2221 gaataattat ggagttgaaa gagaagaatt tatagatgca ttaaaacaaa tctaaacgta
     2281 atgtttaatg tatgaaaaat atgtatataa aataaattgt ggaattacgg ttaatttaag
     2341 ataa
//
LOCUS       DAEOTL010000193         2329 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.198, whole genome shotgun sequence.
ACCESSION   DAEOTL010000193 DAEOTL010000000
VERSION     DAEOTL010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2329
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.198"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            107..505
                     /locus_tag="KRH82_003918"
     CDS             107..505
                     /locus_tag="KRH82_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657164.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLVIVLVVLIFIKRKKKKFY"
     misc_binding    941..1204
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1355..1906
                     /locus_tag="KRH82_003919"
     CDS             1355..1906
                     /locus_tag="KRH82_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBG8657165.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          984 a          216 c          320 g          809 t
ORIGIN      
        1 taatattaaa gataataaga tatataagaa acttgaaaaa atttgtaatt tttagttata
       61 tatatattat aatgaactag ttaaaaattt ttatgagggg gaaaatatga ataagaagaa
      121 aaaattgatt gggatagcta tatcttttct acttataatc agcattataa atccattaca
      181 agtagaagca gaagctatta ttgagtctag tgtatacatt tcttcaataa aagagaatta
      241 tacatatgat aatactaaat ttaaaactat taaatctaaa agtagacata aaagtaggaa
      301 atataataaa agtaaagtaa agttgaaaaa acgaagtata agaactaaaa agtatggata
      361 tcaaactata aataaatata aaagacaaaa cgcaagaaga cataatatcc taacaaaatt
      421 aatattgtcc ataatagtca tatttttggt tatagtttta gtagtgctaa tatttattaa
      481 aagaaagaag aaaaaatttt actaaaaata attaaaagaa tatcattttt ttaatcattg
      541 gtatctattt aataatatga tgtaattaaa atggagtaat attctgtttc aaaggaggca
      601 tataaataca ggaatgagta ttaaatgatg gttaattaag taaatttatt gataaatgta
      661 cttaattaac tttgaagaat ttaattcctc atgaatcaaa atataaaatt acatcaacag
      721 ttattcacaa aattaatata agaagaatta gagccaaaga gcagactatt agaccattaa
      781 agtaattatt catagaattt tgtatatgaa aagaaatgta tagtataatt tacttttttt
      841 ataaaaaata gattacaaaa tatatttttt ataaaaaggt attgacattt tttagaaaaa
      901 agaatatcat tattttaaca acaaaattca atacaataaa ttaaatccta tgacaaggaa
      961 gagtagttaa atttaggttc agtatagaga gctgaggatg gtggaatctt agcaagaaaa
     1021 aatttgatga atggccctta gaggaataaa ttgaaatcat agttttgaga gtagacttta
     1081 tcgtcagtcg cacgttatag cgaataaggt atgtaagtac ctgataatga gatgtatgaa
     1141 aattgaattt tatattaatt tttatataat ttaggtggca acgcggataa tctccgtcct
     1201 attagtttag gacggagttt tttattttac tgaaaattta aaagatagaa ggtggtgaga
     1261 aagatgttat gaatttcaaa agctaaagat gatgatatag taggttggca aaaaaataaa
     1321 ttgaaaatta aaaaaatagg aggaagtaca aaaaatgaaa acaaatacaa aaaaattaac
     1381 tttaaatgca atacttttag cgatgggatt attaatacat caaatcacac cagctatagg
     1441 attaccaatg aagccagatg taccactagc aatgttattt gtaatattgg ttttaaatag
     1501 agatgattat aaaacttgtt tgatagcggg tatagtaaca ggaatattta cagcacttac
     1561 atcaagtttt ccgggaggtc aaattcctaa tgtaatagat aaaactctta cagcaaatat
     1621 agtattttta ttaatgaata ttagttataa tatgcctttt ataaaaaaat tagctaagaa
     1681 aacacaagat actgtagtag ttgcaataat aatgccaata ggaactcttg taagtggaac
     1741 tatcttttta ttagcagctc aagctatagt tggtcttcca ggggcttcat ttacagcttt
     1801 attcttagca gtagtattac cagctgtttt aataaatcta gttgcaggaa tatttttatt
     1861 caagattgtt agtctatcaa taagaagagt tagttatcaa gcttaaacac gaaataatat
     1921 tttactttat aaagcattat aataactaaa taacataaga ataaagtaga ttataactat
     1981 tttattctta tgttgtttaa agatttggta ttatatattt atttttaata aaatatttat
     2041 atagtaccaa ttacacttaa tttaacagat aaattatcat acctatataa tattcttata
     2101 tgtatctcat ttgtagttat taaatataag atatatttaa ttgacttttc aagataaatt
     2161 tttatattaa tctcctctga tttctcattt tttgaataca ctaaaatttc caattaaatc
     2221 aattatatat ttataaagtt ttaaaaatat agtaatgtat atattttttg tgaaaaactt
     2281 gcttaaattt agccaaaaaa aatagataat tcataataaa aaataaagt
//
LOCUS       DAEOTL010000194         2283 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEOTL010000194 DAEOTL010000000
VERSION     DAEOTL010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.199"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            265..1566
                     /locus_tag="KRH82_003920"
     CDS             265..1566
                     /locus_tag="KRH82_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBG8657166.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1642..1917
                     /locus_tag="KRH82_003921"
     CDS             1642..1917
                     /locus_tag="KRH82_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBG8657167.1"
                     /translation="MLELTKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
BASE COUNT          938 a          184 c          448 g          713 t
ORIGIN      
        1 gtgaattata ttgaacaata tattaataat tggtagtaaa gtatatcaaa taagatattg
       61 ctattatgta gtaaattata taaaacaatg tatcagaata aatagtatat taataatttg
      121 tagtatatca tgacgaataa tacagtcata acaaatagtg agtcataaca aataatgtat
      181 ttataattga taatgtattt ataattgata atgtatttaa aaatcaaaat ataaaaactt
      241 ataaggaaag agagattaat ttatatgggt aaatcaaaag atgttgaaat agagaagtct
      301 attttaggca caattctttt agacaataaa ttaagctata agctagatga attaaatgaa
      361 aacatgttta tgaatgatat atgtcttgag atatttaaaa ttatgaaaga acttaaaaaa
      421 gaaaacatag tgattgatgt ggccactgtg aaatcaaaga tagatagaaa atctctagca
      481 ataaaaacaa gtgatgtgac taatctaatt acttggggtc agaattttgg tcttgatggt
      541 catattaaaa ttttaaaaga aaatttagct agaagaagca taaatcaaaa ttgccaaaac
      601 cttttacaca gcctaaacct tggagaaaat atcgatactt gtatttacaa atttgaaagt
      661 aatataaagg agattttgga caaggatact tatgaaaatg atgatgtaaa tagtatagca
      721 gggaaggtgc ttgatttttt agaaaacaaa aaagatattg gatttaaatt tggtataaaa
      781 ttacttgata ccactatagg aggtcttttt aaaggagagc taaccacaat agcagctaaa
      841 tcgggggttg ggaagactgc tttggcactt caaataatgt taaattcatt taagcaaggt
      901 aaaaaaactt tatttataag tagagaaatg accagtgagc aagtatttat gagaaatata
      961 tgcagagtaa ctggtgtaag tacaaggaat atgaaatcta aagaaataga tgaaaatgat
     1021 tggaaactta ttgtaaatgc tataggtgat ttaagcgaaa ataacttaat ttatatcaat
     1081 gataagatag atacaattag tgcaattaga aagaggataa ggcaggtaaa gccagattta
     1141 ttaatagtgg attatgtgca actccttaca tctcagaaaa gcatggataa gagagaaagg
     1201 gaagtagcta ctttttcgag agaacttaaa aatatgactt tagattttaa tatacctgta
     1261 atccaattaa gtcagttaaa tgatgaaatg aaagattcaa gaccttatgg agatagacct
     1321 atgagagata gcaaagccat ctaccacgat agcaacaatg tggtttatat acatcaatta
     1381 aaggggagtg attatgaaga agcagtgaga gatattggag aaagtgagga ggcagttaga
     1441 gcatcagaat acaggggaat taagatggtt gatttaatag ttgcgaagtg tagagatgga
     1501 cagactaggc ataagcattt ttgttacttt ggggataagt tacattttca agaactaaat
     1561 tattaggtca ataaagtagt aataacaagc ttattaaaag tcggggaata gcaaatagat
     1621 tataaaatat gaggtgaaaa tatgttggaa ttaacaaaaa ttatagaatt acttgaagaa
     1681 cacaagatag aagtaagtat tccaaaggag ttacataagt atagtttatt ggaatacctt
     1741 gaattgtgtc aacaaagtgg gggaacatat ttttatatta aaacactgga aggggcttta
     1801 aaagaggcta gaaatgagct tatgattaaa ttgtttaatg ggaaaaatta tatggaatta
     1861 gcgaggatgt ttgaaatgag tgttattaat gtcaggcata ttgttagaaa aaaatagata
     1921 tttttggaga atacaagtgt gatatacttc tgaaatagaa gttattatag ttgaaataaa
     1981 attgtggtta ataaattaaa gttgtgtata agtttaagat tatagaggag tataagtgtg
     2041 attaacagca tgattttgtg aataaaattg aggatatata tgagttaaat gtgtgattaa
     2101 taaggtaagg ttgtgtataa gattatgagt atttaaaagg aggggctata attaatagtg
     2161 tagagttgtg tgtttgctta agattatata ataatttaat agattaaact atactaataa
     2221 ggtaaaatcg tgtgtttagt taaagcttat tataaaatct tgatatgtga ttaatgatgc
     2281 aat
//
LOCUS       DAEOTL010000195         2256 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEOTL010000195 DAEOTL010000000
VERSION     DAEOTL010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.200"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..663)
                     /locus_tag="KRH82_003922"
     CDS             complement(<1..663)
                     /locus_tag="KRH82_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBG8657168.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSK"
     gene            complement(692..1981)
                     /locus_tag="KRH82_003923"
     CDS             complement(692..1981)
                     /locus_tag="KRH82_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBG8657169.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMIAEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT          727 a          408 c          214 g          907 t
ORIGIN      
        1 tttagagttt aaacttttta ggtattctct aacttccagt aaattttcaa gtatcttatg
       61 tgattgtgat ttaatttgct catctggctc ttttaaatct ggtacattta tacatcttat
      121 accaccattg tatgcagctt cgactcccat aggcgaatcc tctatgacaa tacaattttt
      181 gggattaaca tttatctttt tagctgcttt taggaatatc tcagggtttg gtttcgagtt
      241 tacaacatca tctccacaaa ctatagcatc aaagtaatct tttaaatttg ccttagctaa
      301 tctctttact gctctttctc tctttgttga tgttgcaaca gccattttgt atccattttc
      361 ttttaaaaaa gagattagtt cattgactcc taatttgata ggagctccct tcctctccat
      421 aaattcaatc atatttttag ttttttcgtc atataaatct attattggta cagaactatc
      481 gtatatatct gtaagacctt ctattattcc tttacgattt cttcccataa ctgatgtata
      541 aatttcctta gtcatagtat atccatactt ttcaaacgtc tccatccaaa attcaagaga
      601 aattctctct gagtcaaaca aaactccatc catgtcaaaa ataattcctt ctactttttg
      661 catacaattc ctccaatatt ttttgatata attatattac actttttatg attaatttta
      721 caaccctcaa tttatccaat tctaatattg taaaattgta attttcaaaa gttacacttt
      781 ggtttacttt aatatttgaa ccaagcatat aggatatcca cccacctata ctgtcaaatc
      841 catcatgctc tatatcaagt ccaaaatact tattaatata gttgatagat tcagttccat
      901 caactaagta agaacctgct cctattttct taatatgagt ctcttctttg tcaaattcat
      961 cttgaatttc tccaactatc tcttctagta tatcttctat tgttaccaca ccagatgtac
     1021 caccatattc atccacaact atagcaagtt gaagtttttc ctttcttatt ctctcaagag
     1081 ctttatctat agttaaattt tcagatatat atataatatc tctcaatatt tcttctagtt
     1141 caattttatt ttcatttatc ttttgattgt ataaatctct tatatgtaca aaacctaata
     1201 tatcatcttt attttttctg catactggat atcttgtaac accttcctct tttaaaatag
     1261 ctaatatctt ttcttcagaa tcactttcat atatacatac catatcagtt ctaggaacca
     1321 ttatctctct aattttcttt tcttcaaatt caaaaatatt atcaactaat ctttgctctg
     1381 attcatctat aagtccactt ttataacttt cttctactaa tagtcttatt tcgtcacctg
     1441 tatggggttc atcaacctca tcagcttgtg aatatccaaa tggtttaaga aataaatcag
     1501 tacttaagtt gaaaaaatat attattggat atgttaactt ataaaatcct actaataaaa
     1561 aagatgtact caacattatt ttttctgtat tataaagtgc taaagcttta ggaaccaact
     1621 ctcctattac aacctccatc attgttataa ttaaaaaaga aatggaaatt gatatagtat
     1681 atataatact ttcactaaga ttaaatacac ttactattgg taaaattaac tctttaactg
     1741 tagattctcc catccaacct aatgcaagtg aacaaagtgt tataccaagt tgacatgcag
     1801 aaagatagga atttaagttg tcttttatta ttttacatct ttttgcatta ttattacctt
     1861 cagctatcat ggtatcaatc ctagaactac gaagttttac catagcaaat tcacaagcta
     1921 caaaaaaagc atttatcaaa acaagcatta ctataagtgt tacttttaat aactcccgca
     1981 taaagtattg gttcttataa tgtaagaaat ctataagaac tcaaagttcc ccccttatat
     2041 ttataaattt aatttataat atatattcta tcatatttat taatatatcc tactttatta
     2101 caaataattt ttataaacta aataacccct ttaatattta tgactggcta tttgataaat
     2161 attaaagggg ttatttagtt atcatttttt atttctaaaa atcttttctc aaatgattta
     2221 gttatctatt tatccaattt tttacataat ttaatg
//
LOCUS       DAEOTL010000196         2254 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEOTL010000196 DAEOTL010000000
VERSION     DAEOTL010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.201"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(101..1393)
                     /gene="brnQ"
                     /locus_tag="KRH82_003924"
     CDS             complement(101..1393)
                     /gene="brnQ"
                     /locus_tag="KRH82_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBG8657170.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNNNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT          747 a          374 c          246 g          887 t
ORIGIN      
        1 gttcttttat ctacaataat ttaataattc ttttaaatat aaaaaggaat tgcctatata
       61 atttaaaggc aattccataa ttatcaatta gtttttatta ttatgcagtt ttactgcttt
      121 tagatggaat aaagtttcct attattcctg ctattacaac tggaactatc cagttaaatc
      181 ctaatgaagc aaatggtaag ctattaacta gaggaatttt tacaccaaaa cttgttgcaa
      241 ctgttaatac acttactaat aatgccatgt atgcagcaca tttgaacacg ttgttatttt
      301 taattttatt actaaataat gctagtataa ctagagttat agttgctgga tataccatac
      361 ttagtatagg agaagagaat tgtattattg tacttactcc aaagtttgat atgattgcac
      421 taaatacaca aactactata actatatgct catactttaa ttttccatct gtaagtgttg
      481 agaaatattg accagctgct gaagaaagac ctatagctgt tgttaaacat gctaatgcaa
      541 ctataatagc caataaaatt ttacctgtag ttccaagtaa agctgctgtt attgcaacta
      601 ttaaagctgt ttgttgaaca tcttgtccat attgttgaga cacagttgct ccaagataac
      661 ataatccacc ataaactaat gccattccta ttactgcaat tacacctgca cttattgtgg
      721 ctttcatctt ttctttctca cctgtataac ctttagctat tactgacatg attataattg
      781 atgcaaatac actagctgcc aatgcatcca ttgtttgata accttgagtt ataccttctg
      841 caaatacatt ttgtattaaa gaactgtctc ttatttctcc taatggagat acgatacctt
      901 taactattaa tactgccaaa gctataagta aagctggagt taatattgac ccaactatat
      961 ctacaacttt tgatggtctt attgttaaaa ccaatactag agcaaagaat actatagaga
     1021 atattactgg gcttattcca gaacctattg taggtaatat acccatttca taagttgttg
     1081 ctgctgttct aggtattgct aaaagtggcc ctatacagat taccattgca catcctaatg
     1141 caatacttaa tcctttgcct gctcttgaga acatcttcga tgtgtctcca ttgaacttag
     1201 ttgctgctat aactgctaat aatgccaaac caccatctgc aaaaaggaat cctatgaaag
     1261 ctactagcca actacttcca gataaaactc ctagatatgg agggaagatt aagttccctg
     1321 caccaaaaaa cattgcaaat agtgcaaatc caattacaat tacatcttta aaattgattt
     1381 gtttctcacc catttaaagc acccccattt gaattttact accttttact aaaaaataag
     1441 tccaatctct taattaaatg aaaacctttt gacgagattt tatttaatta tacatttttg
     1501 acttaaattt gtcaattatg tttcataatt tataaaatct tcacaatatt taatacaact
     1561 ttcttaatta aacaaaatca acctgtatac tttaaacata gttggttttt tgttttttct
     1621 ctaatttttc ttgataaaat taactattcc gaataattaa aatattaaga ctttttagat
     1681 tattcgattt attattaagt tgtattgctt tatatactgt atatatcact ctcctttttt
     1741 acattcatat aatcttttta attcaattta aattttaaat attttgtgtt tattatataa
     1801 tctgaaaaaa aagcagtcaa tagcattttt aattttttta attttcaaaa ttatgattct
     1861 taaaaaatcg ttttcctttt atcataacac ctatttacgt taattcttgt agtattttgt
     1921 atttattttg ctaaattgac agttaacttt attcaatttt tattctactt gcatagattt
     1981 gcctcttgtt ttttactctt aaaaccattt tttctgaaaa ttccttatta tgatttatca
     2041 acttattttt cttcataaca attactctct aacttccaac ttacttaaac tttgcagttg
     2101 ctagtattca cgtttacata cttatatgtc ataattaact aaaaattctt aatatatctc
     2161 tcaatgaaaa caatttactc atttatttaa tacatttata taatcatatg tcttaaattt
     2221 tgttttatta ttttattatt gtcacaattt tatt
//
LOCUS       DAEOTL010000197         2187 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEOTL010000197 DAEOTL010000000
VERSION     DAEOTL010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2187
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.202"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(35..211)
                     /locus_tag="KRH82_003925"
     CDS             complement(35..211)
                     /locus_tag="KRH82_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657171.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(266..363)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            604..987
                     /locus_tag="KRH82_003926"
                     /pseudo
     CDS             604..987
                     /locus_tag="KRH82_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      1343..1436
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1519..2004
                     /locus_tag="KRH82_003927"
     CDS             1519..2004
                     /locus_tag="KRH82_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBG8657172.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
BASE COUNT          948 a          215 c          304 g          720 t
ORIGIN      
        1 aactaaaaag ggttttctag aaatcaatgt ctatctaatt atacttactt accaatacca
       61 ttacttggtg taaacaagac tctactacat tttctccgta ctctaatata aaatcatcta
      121 actgtgtatc taaaaaatta caataatcat acgaactgct aatataagca gtcaatacat
      181 gtgtacattt atccatttta tttccaaaca tataaattat tatcccccta aaaaactttc
      241 ataaaaacaa aaagaacact atctctttgg caactggctg acataactca taagatattt
      301 atataagtct tagtccctat agctttgcgt cactaaattt ctctagtttt gccgatttag
      361 ttttattcta caactaaaat aatacaatag aattagttat tattcaacag gattgtttga
      421 aagttaaata aatttataga tatgaacatt attttacact taaaaacaga ctaaacacgt
      481 agagtacctg gtaaaaatta aatatagttt ttgttctaaa aagctcctat tataatttaa
      541 gctagataaa tttgaagaag tgacataaga agaagtgaca taaattgaaa gaaggaatat
      601 attatgctaa ataaaaaatt accagataca gaattaaaaa ttatgaaatg catatggaat
      661 actggttata aaactgtaat atcaaaagat gttgcagatg aaatagaaaa aacatatggt
      721 tggaagcata caactacaat tatactttta gctagattaa ccaaaaaagg ttttttaata
      781 tcatagagaa ttgggaggca tgtacactat acagtattaa taaaagagag agaatatctc
      841 aaaatagagg gaaaaagagt ttttagaggt ttacataaca atcctttatc agaattaatt
      901 tcaaaattac atgatggaga agaaataact gaagaaaaaa taatagaaat aggaagttgg
      961 ataaaaagct ggaaatataa agattaataa ataaaaggta gctaataata taagtgctac
     1021 cttttttatg tggataatat tggtgataag ttgtggaaaa cttatataaa aattgtggat
     1081 aaagtgtttt gctgacattt tactgacaaa agttaaaaaa ataaatgtta tatatattgt
     1141 aaaatgttga aaaatagcca tatatataaa atataagtaa cactatagat aaattactgt
     1201 cttttatatt gactataaag aacagtaatt gaataaatat aaagatattt tttgattatt
     1261 attaattaaa aatttaattt atatttaaat aatataaaat ttgaggtaat attatttttt
     1321 aattgttcaa attatgttat tattcagata taggcaatat tagataaatc taatgacgca
     1381 aaactatagg gactaaaatc tttatgtaat aaaggtcatg tcagccagtt gccaaaaaga
     1441 taataattct ttttgttaaa agtattttta gagttatata ttttaataac ttaatatttg
     1501 gcaagaggag ggcttaagat gatatctgaa ttaatgttaa aaaattttcg caaatctagc
     1561 atcaatttta agactaaaat taaattgaat ttaagagaaa aaccagacat aaatagtttg
     1621 aaattaaaaa gtataccaga aggtaaaatt gttaagttaa agtgtgtaga tggaatatgg
     1681 gcagaagttg agagtaatta tgacaaaggt tggttacttt ataaatattt agaaagatta
     1741 agtaatgcta aaaacaatag taatgataca ataaaaaata gaaaaaagaa ttacatagga
     1801 aatataagaa caaatggatt aagtttagaa cttagaaatg atagaacatt agaatctaaa
     1861 gttataacta caatccctga tggttttaaa gttgaagtat gttatagcgt tggaaaatgg
     1921 gcaagagtta atatcaataa aaatgaaaaa cgatattctg gatatgtata taatcaatac
     1981 atagaagagc atttaagttt ataatacgat actagcaagc tttaaatata ttaataaatc
     2041 acaaaaaaga atcccattaa tgggattctt ttttgtagaa acattataac agaactaaag
     2101 agaataaatt aactaattta tttttattat aaagtaatta taaatggtaa atttaattga
     2161 aagtagattt aacttatact ttataca
//
LOCUS       DAEOTL010000198         2142 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEOTL010000198 DAEOTL010000000
VERSION     DAEOTL010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2142
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.203"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>2142
                     /locus_tag="KRH82_003928"
     rRNA            <1..>2142
                     /locus_tag="KRH82_003928"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          583 a          461 c          638 g          460 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tactaccgat aaccgtttga gagaagggat
      781 gacacagtag gataagctaa gcacactgtt ggttatgtgt gcccaagcat tgaggcagtc
      841 aaagtaggca aatccgcttt gataatgctg ggatgtgatg gggagcgaaa tttagtagcg
      901 aagtagctga tttcacactg tcaagaaaag tctctatcga ggttaaaggt acccgtaccg
      961 caaaccgaca caggtgggtg aggagagtat cctaaggcca gcgagagaac tgttgttaag
     1021 gaactcggca aaatgacccc gtaacttagg gataaggggt gccaccatca ggtggccgca
     1081 gagaataggc ccaagcgact gtttaccaaa aacataggtt tctgctaagt cgcaagacga
     1141 tgtataggag ctgacgcctg cccggtgctg gaaggttaag gggatctgtt agagcaatcg
     1201 aagcagtgaa cttaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg
     1261 aaattccttg tcgggtaagt tccgacccgc acgaaaggcg taacgatttg ggcactgtct
     1321 caacaacaga ctcggtgaaa ttgtaattcc ggtgaagatg ccggatacct gcgacaggac
     1381 ggaaagaccc catggagctt tactgtagct tgacattggg tcttggtact acatgtacag
     1441 gataggtggg aggctttgaa accaggacgc cagttttggc ggagccatcc ttgggatacc
     1501 acccttgtag tactgggact ctaaccatag gccatgaatc tggtcttggg acactgtcag
     1561 gtgggcagtt tgactggggc ggtcgcctcc caaaaggtaa cggaggcgct caaaggttct
     1621 ctcagtacgg tcggaaatcg tacgtagagt gtaaaggcaa aagagagctt gattgcaaga
     1681 catacaggtc gagcaaggat gaaaatcgga cttagtgatc cggtggttct gcgtggaagg
     1741 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtc
     1801 cacatcgacg gggaggtttg gcacctcgat gtcggctcat cacatcctgg ggctgtagta
     1861 ggtcccaagg gttgggctgt tcgcccatta aagtggtacg cgagctgggt tcagaacgtc
     1921 gtgagacagt tcggtcccta tccgtcgcag gcgtaggaaa tttgagaaga cctgtcctta
     1981 gtacgagagg accgggatgg acgtacctct ggtgtaccag ttgtcctgcc aagggcatgg
     2041 ctgggtagct atgtacggaa tggataagcg ctgaaagcat ctaagcgcga agccaacttc
     2101 aagataagat ttcccaccgc aagggtaaga ccccagaaag ac
//
LOCUS       DAEOTL010000199         2104 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.204, whole genome shotgun sequence.
ACCESSION   DAEOTL010000199 DAEOTL010000000
VERSION     DAEOTL010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.204"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..903
                     /locus_tag="KRH82_003929"
     CDS             <1..903
                     /locus_tag="KRH82_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657173.1"
                     /translation="LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEV
                     RAENGSLKLMNNLVWEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKN
                     ADLADLGTVMGNVYHTKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPC
                     FLIFDEYVAFFEMLGTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRD
                     NFNFRVGLGRISELGYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGH
                     DFLQTIGRLAQERQVMPEQQGKEN"
     gene            907..1323
                     /locus_tag="KRH82_003930"
     CDS             907..1323
                     /locus_tag="KRH82_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657174.1"
                     /translation="MEIKEINKIIQSEDKDEKSKSVKCICINYGDFLADCEGFVQKRY
                     HDFKCNPKHQFEKKADTILENAIHEKNFMPDLFLIRLNRKQSACNSQIDFVFELLDKS
                     FLETDPIRKSEISEETLNLCLSADVSFIMVYIGMNR"
     gene            1568..>2104
                     /locus_tag="KRH82_003931"
     CDS             1568..>2104
                     /locus_tag="KRH82_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8657175.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLALASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGRYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTG"
BASE COUNT          661 a          394 c          495 g          554 t
ORIGIN      
        1 cttttacggt tagaggataa attggaaagt ggcttgtatt gcgagctgac cgacaagacc
       61 ctgcatgacg gctatatcga atataccctg ctttatgata tgatagcgaa ccgcattacc
      121 attgatgaag tacgggcaga aaacggcagt ctgaaactga tgaacaatct tgtctgggaa
      181 tatgacgcac tccctcacgc tctgattgct ggtggaacgg gtggcggtaa aacctatttc
      241 ctgctgacgc tcattgaagc cttactgcat accaacgctg tcctttatat cttagacccg
      301 aagaacgctg accttgcaga cttagggaca gttatgggaa atgtgtatca caccaaagaa
      361 gaaatgatag attgcgtcaa tgccttttat gagggcatgg tacagcgaag tgaggaaatg
      421 aagcgacacc cgaactataa gactggcgaa aactacgcct atctgggact tccaccctgc
      481 tttcttatct ttgatgaata tgtagcattt tttgaaatgc ttgggacgaa agaaagcgtg
      541 agcctgctta gccagttaaa gaaaatcgtt atgttgggac gacaagcagg atatttcctt
      601 atcgttgcct gccagcgtcc agacgcaaag tatttttcag acggtatcag agataacttc
      661 aatttccgtg tgggacttgg gcgtatcagt gaattaggtt acggtatgct gtttggttca
      721 gacgtgaaaa agcagttttt ccagaagcgt atcaaggggc gtggttattg tgatgtggga
      781 acaagcgtga taagtgaatt ttacacgcct ttagtcccga aaggacatga ttttttgcag
      841 actatcggca ggcttgcaca agaaagacaa gttatgccag aacaacaagg aaaggagaac
      901 taactcatgg aaataaaaga aatcaataaa ataatacaat cagaagataa agacgagaaa
      961 tctaagagcg taaaatgtat ctgtatcaat tatggagatt ttctagccga ttgcgaggga
     1021 tttgtgcaga aacgttatca cgattttaaa tgtaatccaa aacatcagtt tgagaaaaaa
     1081 gctgatacta ttcttgaaaa tgcaattcac gaaaaaaact tcatgcccga tttgttcttg
     1141 atacgcttaa atagaaaaca gtcggcttgc aacagccaga ttgattttgt ttttgaattg
     1201 cttgataagt cttttctgga aacagaccct atccgtaaaa gtgaaatatc agaagaaaca
     1261 ttaaatttat gtttatccgc tgatgtttca ttcatcatgg tttacattgg tatgaacagg
     1321 taggataagt tctgcctgca caacggcagg aacggtcggc ggagcaaata cgaccgtgga
     1381 agccgttttg cagagcaggg cttgtccctg ctctgctgat gaacccctcg gtatctaaca
     1441 gaggggtacg tttgcaaata aacaatagac aaaaaacata ggaaacataa ggcttctgac
     1501 atggtttcct agtaaaaatc ggctgtgaag tcgccttaaa aaacttcaca ctttacagat
     1561 tgggggtatg gttctgaatg aagaacaatg gataaaagaa ttacgggaga aacggattgc
     1621 ttatggtatc tcacaaggca ggctggcgtt ggcttctggt atcacaaggg aatatctcaa
     1681 caagatagaa agtggaaaaa tgaagccgtc aaaagaactt ctggaaactc tgcataaaga
     1741 actggcaagg ttcaatccag aagcaccgct taccatgctg tttgattatg tgaaaatccg
     1801 ttttcccacg ctggatatac agcacatcat caaagacata ttaaaactga atatcaacta
     1861 tatgctccat gaagattacg ggcgttacag ttatacggag cattattctt taggggacat
     1921 ctttatctat acgtcggctg acgaagaaaa aggtgtcctt ttagagttaa aggggcgtgg
     1981 gtgcaggcag tttgaaagtt acctgctggc acagcaaaga agctggtatg actttctcat
     2041 ggacgcactc gtagacggtg gcgtgatgaa gcgtatcgac cttgctatca acgaccatac
     2101 gggc
//
LOCUS       DAEOTL010000200         2022 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEOTL010000200 DAEOTL010000000
VERSION     DAEOTL010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2022
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.205"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            96..314
                     /locus_tag="KRH82_003932"
     CDS             96..314
                     /locus_tag="KRH82_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016293139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8657176.1"
                     /translation="MKGVLIVISDTQNAQSPTKEKKTYTVEEIAEQLDISKKVAYSLV
                     KSGQFSYVRAGKAIRVSKVSFDKWLNEI"
     gene            333..1778
                     /locus_tag="KRH82_003933"
     CDS             333..1778
                     /locus_tag="KRH82_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
                     /protein_id="HBG8657177.1"
                     /translation="MASIKQRKSSFSVIYWYLDSAGERKQKWDTLETRKEAKQRKAFI
                     EYYQEKFGYVIVPLEEQFAHQIENSKKELDVVDKDITLRDFLEIFVNLYGTSKWSPST
                     FSSKVGSIENYINPIIGDWKLNEITTKSLSKYYNDLLSVPEVPRANRKATGRCVQPAN
                     IKKIHDIIRCALNQAIRWEYIDTNKRNPASLATLPKIPKTRRKVWSVQTFREAVKATE
                     DDLLSICMHLAFSCSMRIGEITGLTWEDVIIDEESIATNNAKVIINKELSRVNAEAMQ
                     KLKEKDILKIFPTQKPHCTTRLVLKTPKTETSNRVVWLPKTVAELLVQYKKDQQELKE
                     FLGSAYNDYNLVIALDNGNPVESRIVRDRFQKLCEENDYEVVVFHSLRHLSTGYKLKM
                     TNGDVKSVQGDTGHAEAEMVTDVYSEIIDEDRRFNAQKMDKEFYSTLNDDTDNPKQDT
                     DLTDSDMALLELIKSLSPEMKEQFLKQALQR"
BASE COUNT          768 a          309 c          398 g          547 t
ORIGIN      
        1 taattgatag tttcagcaac aaaatctatc tactcttttt atttaggtgt gttataatga
       61 ccttattaga cgagtgtatt ttgttgctgt cacaaatgaa aggggtctta atagtgataa
      121 gtgatacaca aaatgcacaa tctcctacaa aggaaaaaaa gacttataca gtagaggaaa
      181 ttgctgaaca actggacatt agcaaaaagg tagcttattc attagtaaaa agcggtcaat
      241 tcagttatgt tcgtgctggt aaagccatac gggtatcaaa ggtttctttc gataaatggt
      301 taaatgaaat ttaactataa ggagagaaaa ttatggcttc aatcaaacaa agaaaatcaa
      361 gtttttcagt tatttattgg tacttagata gtgcaggaga aagaaaacaa aaatgggaca
      421 cgctggaaac aagaaaagaa gcaaaacagc gaaaagcctt tatagaatac tatcaagaga
      481 aatttggata tgtgatagtt ccattagagg aacaatttgc acatcagatt gaaaattcta
      541 aaaaggagtt agatgttgta gacaaagata ttacattgcg tgatttccta gaaatttttg
      601 ttaatttata tggcacatct aaatggtcgc cgagtacatt tagtagtaag gtaggcagta
      661 ttgaaaatta tatcaatccg attattggag attggaaact gaatgaaata actacaaaaa
      721 gtctatcaaa atactacaat gatttattga gcgttccaga agtaccacgg gcaaacagaa
      781 aagcaactgg tcgttgtgtt caaccagcga acatcaaaaa aatacatgat attatccgct
      841 gtgccttaaa tcaagctatc cgctgggagt atattgatac aaacaaaaga aaccctgcgt
      901 ctttggctac gttaccaaaa attccaaaga ctaggcgaaa agtgtggagt gttcaaacat
      961 ttcgagaagc ggtaaaagcc acggaagatg atttgctttc aatttgtatg cacttagctt
     1021 tttcctgctc tatgcgaatt ggagaaatta caggacttac atgggaagat gttattattg
     1081 atgaagagtc cattgctaca aataatgcaa aggtaatcat caataaagaa ctttcaagag
     1141 taaatgcaga agctatgcag aaattaaagg aaaaggatat tttaaagatt ttcccaacgc
     1201 aaaaaccgca ttgtaccaca aggcttgtct tgaaaacgcc aaaaacagaa acaagtaatc
     1261 gtgttgtctg gttacctaaa acagttgcgg aactattggt gcaatataaa aaagaccagc
     1321 aggaattaaa ggaattttta ggaagtgcct acaatgatta caaccttgtt attgcgttgg
     1381 ataatggcaa tcccgtggaa agccgtattg ttagagatag gtttcaaaag ctctgtgaag
     1441 aaaacgatta tgaagttgtg gtatttcaca gcctacgcca tttaagtacg ggttataaac
     1501 tcaaaatgac aaacggagat gttaagtccg tacaaggcga tactggtcac gcagaagcag
     1561 aaatggttac agatgtatat tcagaaatca ttgacgagga cagacgtttc aatgcacaaa
     1621 aaatggataa agaattttat tctacgctta atgatgatac agacaatcca aagcaagata
     1681 ccgacttaac cgatagtgat atggcgttat tggaactgat taaatcttta tcgccagaaa
     1741 tgaaagagca atttttaaag caggcacttc aaagatagaa tttcaaaagt gttagcaaat
     1801 tccaaaaaaa ccagcgattt ttcttcaaaa ataaaaaagt gttagcaagc ctatttcctt
     1861 aaaagtctta aaaaaatatc gaataaaaaa tgacagattg aaaacaattc gtattcagcg
     1921 taaatagaaa gccataaata aagaaacgct gaaaaccttg taaaataagg ctttcagcgg
     1981 agtttgtggc gtcccagaca ggagtcgaac ctgcgacgtt tc
//
LOCUS       DAEOTL010000201         1990 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.206, whole genome shotgun sequence.
ACCESSION   DAEOTL010000201 DAEOTL010000000
VERSION     DAEOTL010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1990
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.206"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..353)
                     /locus_tag="KRH82_003934"
     CDS             complement(<1..353)
                     /locus_tag="KRH82_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBG8657178.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEA"
     gene            complement(353..>1990)
                     /locus_tag="KRH82_003935"
     CDS             complement(353..>1990)
                     /locus_tag="KRH82_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657179.1"
                     /translation="FYFQQQQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHA
                     YQAGSETSSNVVDALDSVDELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKD
                     FYDDLNVKLVRPAGDMLGLHSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENT
                     GIYMGYSVDTGRNVYLQPSLASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVL
                     FGGQALLLDPKSERGNWKETLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESL
                     AIDILTFLTGISSRDGEKFPVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADH
                     IDSFTDYDFAHLLFSDGTVENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVS
                     MLIVISTFALDFIHSDRSIFKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFV
                     TQSAYDVSKESLKNNIGLKFAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQC
                     LLQDLYGRVGVVQIHPVFEELLHAFDTRPPVQRNEVE"
BASE COUNT          531 a          481 c          409 g          569 t
ORIGIN      
        1 taggcttcct gcaccacata gccagttgca ttgcttaaat aaaggcttat cgtccagaca
       61 aagttggtaa tgcagtaaag cccgtactgt accgattttc cgataccgtc cagccagttc
      121 cacggaagcc acgaccagct attatcgacg aaaaaatcaa gctggtagtt ggaaagcgga
      181 tattttgaat atagattttc tgcgtttatg gtatcgtcca caagccccgt cgcatgagcc
      241 accgtcccca gaagtgaaag caggataagg gaaagtgcca ccacgaacag agccattttg
      301 agaaagtgaa gtatcttcct ttttgtgaac gcactctgta tcctttcttt catcactcca
      361 cctcatttct ctgtacgggc ggtctagtat caaaggcgtg tagtaattct tcaaagactg
      421 ggtgtatctg caccacaccg acacgcccgt ataagtcctg caataaacat tgtccgttct
      481 ccaaatcacg caagcgtttc tggttgtttt cgtcgtcctt gtcgataccg aaaaattcta
      541 aggtctgctt tatctcgttg atgtcagtag aacgaaatgc aaacttcaaa ccgatattgt
      601 ttttcagact ttcctttgac acgtcatagg cagactgggt aacgaaataa acgcctgcct
      661 gcatagctcg tccagcacga accagcttat ttgatagggt ttcgccttgt gccacattta
      721 agaacgccca cgcttcgtcc aaatctacaa tcttaaaaat gcttctgtcc gaatggataa
      781 aatcaagggc aaaggtacta atcacaatca gcatagacac cgacaataat tcaatggtcg
      841 tgtattcctc aaaagtggta tctttatctg gcagtacaag gtctgctact tgaatgatat
      901 tgagctggtt atcaaggctt atagcatttt ctaccgtccc gtctgaaaac agcaggtgtg
      961 caaagtcgta gtccgtgaag ctgtcgatat ggtctgcgat attgcgtgag atagcggtat
     1021 cttcttttct caattcctca ataacgtgta acagtcctct attttcactc tgggtaacag
     1081 aacgcaccgc ttttcgtaac acggggaatt tttcgccgtc cctagaggaa atacccgtaa
     1141 ggaatgttaa gatgtcgatt gccagacttt cagcgtcttt cacattcttc ataatcacaa
     1201 atgggtcaag aagtcctgca ttgtccttgt cgctggtaag gtttacgata ttgatttcat
     1261 gggctatctc tgggagcgtt tctttccagt tgccacgctc acttttaggg tctaacagaa
     1321 gtgcttgacc gccaaacagc accgcataat atacaagtag attgttgcag aatgactttc
     1381 caccgccaag acttcccaca aaagcagaag caagggcatt agtaactgtg ccttttactc
     1441 cctgcgaagc taaagacggt tgcaggtaca catttcttcc cgtatcaacg gaatagccca
     1501 tatagatacc cgtgttttcc cctaactgct gggtcgcacc aaaaccaagc ccagccaaga
     1561 agtctgactt tacatactgc acatagtcat tgatatatcg cttgctggca ggtaaaaatt
     1621 cagaatgaag tcccaacata tcgccagcag gacgcaccag ttttacattg aggtcgtcgt
     1681 aaaagtcctt gacttcatca caacggcgtt tcagctcgtc aagatcgggt gcagacaccc
     1741 gtatgacgta gcttaactta tacatacttt ctttgctctg gtctaaatcg gtttccagct
     1801 cgtccacgct gtctaaagcg tccaccacat ttgagctggt ttcacttcct gcttgatagg
     1861 cgtgattatc caaatctttc aattcctttt tcttgttgcg gactgtcgtt aatgccttac
     1921 ggttctccac gatttctaca ttcatagaag tatcaacggg gaatgtgaat tgctgttgct
     1981 ggaaatagaa
//
LOCUS       DAEOTL010000202         1982 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEOTL010000202 DAEOTL010000000
VERSION     DAEOTL010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.207"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..>1982)
                     /locus_tag="KRH82_003936"
     CDS             complement(<1..>1982)
                     /locus_tag="KRH82_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657180.1"
                     /translation="HTLMNDFVSMPNDEINRYMKMEKLLENKISRRFKVRRLEINDFG
                     YLMEHLYGRNGIAYEDYEYQLPKKKLNKETLIKYYDLIRPTRCVIEESQRYLRLEHED
                     KESYVSYFTVNAIVGELDFPSSEIFYFQQQQFTFPVDTSMNVEIVENRKALTTVRNKK
                     KELKDLDNHAYQAGSETSSNVVDALDSVDELETDLDQTKESMYKLSYVVRVSADDLDE
                     LKRRCDEVKDFYDDLNVKLVRPAGDMLGLHSEFLPASKRYINDYVQYVKSDFLAGLGF
                     GATQQLGETTGIYMGYSVDTGRNVYLQPSLASQGIKGTVTNALASAFVGSLGGGKSFC
                     NNLLVYYSVLFGGQAVILDPKSERGNWKETLPEIAHEINIVNLTSDKGNAGLLDPFVI
                     MKNVKDAESLAIDILTFLTGISSRDGEKFPVLRKAVRSVTQSNSRGLLHVIDELRRED
                     TPISRNIADHIDSFTDYDFAHLLFSDGTVENAISLDNQLNIIQVADLVLPDKDTTFEE
                     YTTIELLSVSMLIVISTFALDFIHSDRSIFKIVDLDEAWAFLNVAQGETLSNKLVRAG
                     RAMQAGVYFVTQSAYDVSKESLKNNIGLKFAFRSTDINEIKQTLEFFGIDKDDENNQK
                     RLRDLENGQCLLQDLYGRVGVVQIHPVFEELLHAFDT"
BASE COUNT          535 a          466 c          396 g          585 t
ORIGIN      
        1 gtatcaaagg cgtgtagcag ttcttcaaag acggggtgta tctgcaccac accgacacgt
       61 ccgtataagt cctgcaataa gcattgtccg ttctctaaat cacgcaagcg tttctggttg
      121 ttctcgtcgt ccttgtcgat accaaaaaac tctaaggtct gttttatctc gttaatgtca
      181 gtagaacgaa aggcaaactt caagccgata ttgtttttca gactttcctt tgaaacatca
      241 taggcagact gggtaacaaa ataaacgcct gcctgcatag ctcgtccagc acgaaccagc
      301 ttgttagaga gcgtttctcc ttgtgccaca tttaagaacg cccacgcttc gtcaaggtct
      361 acaatcttaa aaatacttct gtccgaatgg ataaaatcaa gggcaaaggt actaatcaca
      421 atcagcatag aaaccgataa taattcaatg gtcgtgtatt cctcaaaagt ggtatcttta
      481 tctggcagta caaggtcagc tacttgaatg atgttgagct ggttatccag actgatagca
      541 ttttctaccg tcccgtctga aaacagcaga tgtgcaaagt cgtagtccgt gaagctgtcg
      601 atatggtctg cgatatttct tgatatgggc gtatcttcac ggcgtagctc gtctatcaca
      661 tggagcaagc cccgactgtt gctctgggta acggagcgta ccgctttacg aagtacgggg
      721 aatttttcgc cgtccctaga ggaaataccc gtaaggaatg ttaagatgtc gattgccaga
      781 ctttcagcgt cttttacatt cttcataatc acgaatgggt caagaagtcc tgcatttcct
      841 ttatcgctgg ttaagtttac gatattgatt tcatgtgcga tttctggaag tgtttccttc
      901 cagttgccac gctctgattt tgggtctaag ataaccgcct gtcccccaaa gagaaccgaa
      961 taatacacca gaagattgtt acagaacgac tttccaccgc caagcgaacc gacaaaagca
     1021 gacgcaaggg cgttggtaac tgtacctttt ataccttgac tggcaaggga cggttgcagg
     1081 tacacatttc ttcccgtatc aacggaatag cccatataga tacccgtagt ttctcctaac
     1141 tgctgtgtcg caccaaagcc aagcccagct aaaaaatctg attttacata ctgcacataa
     1201 tcattgatat atcgcttgct ggcaggtaaa aattcagaat gaagccccag catatcccca
     1261 gcaggacgca ccagctttac attgaggtcg tcgtaaaagt ccttgacttc atcacaacgg
     1321 cgttttaatt cgtccaaatc atcagccgat acacgcacta cataagagag cttatacata
     1381 ctttcttttg tctggtctaa gtccgtttcc agctcatcca cgctgtctaa tgcgtccacc
     1441 acatttgaac tggtttcact tcctgcttga taggcgtgat tatccaaatc tttcaattcc
     1501 tttttcttat ttcttactgt ggtaagagcc tttcgattct ccacgatttc tacattcata
     1561 gaagtatcaa cggggaatgt gaattgctgt tgttggaaat agaagatttc acttgacgga
     1621 aaatcaagct ccccgacaat cgcattgacg gtaaagtagg acacatagct ttccttgtcc
     1681 tcatgttcca atcgtaaata ccgctggctt tcctcaatca cacaccttgt cggacggata
     1741 aggtcgtagt attttatcag cgtttctttg ttcaatttct tctttggtaa ctgatactca
     1801 taatcttcat aggcgatacc gttcctgccg taaagatgtt ccatgagata cccaaaatca
     1861 ttgatttcca agcgacgcac cttgaagcga cgggagattt tattttccag taacttttcc
     1921 attttcatgt aacggttgat ttcatcattc ggcatggaaa caaaatcatt catcagcgtg
     1981 tg
//
LOCUS       DAEOTL010000203         1960 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEOTL010000203 DAEOTL010000000
VERSION     DAEOTL010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1960
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.208"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(43..234)
                     /locus_tag="KRH82_003937"
                     /pseudo
     CDS             complement(43..234)
                     /locus_tag="KRH82_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            504..1145
                     /locus_tag="KRH82_003938"
     CDS             504..1145
                     /locus_tag="KRH82_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBG8657181.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            1463..>1960
                     /locus_tag="KRH82_003939"
     CDS             1463..>1960
                     /locus_tag="KRH82_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657182.1"
                     /translation="MKKTLKRLCTGFLALATIVTALPTTPVHAESKQYWTESAERVGI
                     IEKVMNDGSIGSTFNEGMMKVEGKTAYCIDINTDFRNGYKTRADASSRMNANQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGAR"
BASE COUNT          689 a          297 c          328 g          646 t
ORIGIN      
        1 taactcatga ctaaagtcac gagtgtgcgt agctattttt taatcaaagt gtacaacttc
       61 tatacctttt tctattaaat tcaatgtaac tcttttatat aacttgtcta atggctctac
      121 atttggagta gtaactaaca aacatttctt tccatatttt cctattattc taggtaattc
      181 acttaaagtt ccttgtccaa aatttattct tgatggttga taaaagttaa tcatattttt
      241 cctcccttaa attattgcct tcatattcaa attatacata tcataggatt tttaaggcaa
      301 taccttcact gttaactctt atttactaaa gcttatggca attattagac aataaatgtt
      361 ttattattac catatcatta tgtaaatttt attaagtacc catgttataa ttttataatc
      421 aatcttattg tataattgac ttaataataa aaatagagta tatacacttt tttatgacaa
      481 atagcttaaa ggagaattaa attatgaaat atttgataga cagtgctaat cttgatgaaa
      541 ttcaaaagtg tttaaagtat ggatttaagg gaataacagc taatccatct atgtatctta
      601 aagagaaagt aaacttccat gaatttattg agacatgtgc taatttaaat ccagaaatat
      661 taactgctga agtcattgga aataatttat acgaattaat taattcatgt gataagatat
      721 taaatataaa taaaaacact ataataaaaa taaatttctc tgaagttggc ttagaactta
      781 taaacatatt aaatagtaaa ggtgtaaaaa ctgcatgtac cttgattttc aatgtaaatc
      841 aagcatcatt agctataaat gcaggtgctg attacctatt cccttttata ggtagaaatg
      901 atgaaaatgg gaatgatggt ataaaaaacc ttacagaaat atgtaacctt atatcaataa
      961 atggatataa tactaaagtt gttgcagctt ctattaaaaa tgtattccac ttaactcaag
     1021 catctctttg tggatgtgat tatgcagctg taacatatga tttatttaaa aaagcttctt
     1081 ttaaccagct cacaatagat ggtgccaata cttttgaaag agattggtcc aaggttaata
     1141 aatagtaact aagatttagg agttctctgc gaaccgtggt agctagaagt tcgattatcc
     1201 tcttgggagc gtttaatgcc gtaaattaaa gcataagtgc ttgttatgtt taattgttga
     1261 tactctctgg tgtaccctca tacaccgtag agtgttagca ggttgttagc aacaaaggct
     1321 aatttaaagc tttaatttat cagaaaacat tacaaacaaa ctataaatca tttatcacta
     1381 gaaatcaaga tactcgtatg ttatagacgt tcagaaatga gcgtctattt ttataccaaa
     1441 aatgaaagga gtattaaaat ttatgaaaaa gacattgaaa cgattgtgta cgggcttctt
     1501 agctcttgca actatcgtta ctgctttacc gactacaccc gttcatgcag aaagtaagca
     1561 atactggaca gaaagtgcag agcgtgtcgg tatcattgaa aaagtaatga atgacggttc
     1621 tatcggctcg acattcaatg agggcatgat gaaagttgag ggcaaaacag cctattgtat
     1681 cgacattaac acagatttta ggaatggcta caagaccaga gctgacgcaa gctcacgcat
     1741 gaatgccaac cagatttcag atgtggcgtt atccttagag tatgtcaaac agtatggcga
     1801 agctcacaag gaactgaact acaagcaagt ctatctgttg gaacaatgtg tagtctggca
     1861 gagattgagc gtacatcttg gctggcaatg cgataacgtg cgagcttctt atgatgaaat
     1921 tccaaaggca acgcaggacg aagttttctc tggtgcaaga
//
LOCUS       DAEOTL010000204         1924 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEOTL010000204 DAEOTL010000000
VERSION     DAEOTL010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.209"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            157..441
                     /locus_tag="KRH82_003940"
     CDS             157..441
                     /locus_tag="KRH82_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657183.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(1212..1427)
                     /locus_tag="KRH82_003941"
     CDS             complement(1212..1427)
                     /locus_tag="KRH82_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657184.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(1438..1905)
                     /locus_tag="KRH82_003942"
     CDS             complement(1438..1905)
                     /locus_tag="KRH82_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBG8657185.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFFDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGCCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
BASE COUNT          784 a          207 c          235 g          698 t
ORIGIN      
        1 actaatatac atttaaaaat tataatttaa agcattaaaa aataaatttg tattttgttt
       61 tatataaagt aatttgaaga atatggaaaa acttgattag tacattatta attagggtat
      121 aaaatggtgt aaatagaatg ataaggggtg gatgaaatgc ttgtatataa taaaagtttt
      181 tatcctaatg acatatttcc aagattagat ttttcaaaaa taaaaaaaca gttaaaattg
      241 atagataatg acctgtcaga ttttggaagc atatgtataa tagaaaaaga acattataca
      301 ataagtgtaa acagtatagg tgaaataaat gtgtattatg atttagagta cgaaaataag
      361 gtgtatagaa tagtttatga gattgaaaag ttatttaaat ctcaagttgg aaggtttagc
      421 atatctacat acagaaattg ataattaaaa aagtagaaat taaaaaactt aatactaaag
      481 atatagataa atatatgagg taacagctag agagagttgt tacccttttt aaatactaag
      541 tatatattat tcttattaat tttttgtaaa ttcactaaaa gaccttttta tagaatatta
      601 ttttcttttt ttattaaata ggtaaatcag taaaaatgca attccagttc caattattat
      661 tccaatgata ttttctataa ttaatttttt taatataaaa gtaaataata aaaatgctat
      721 acataaacct aaaatatatc ctttaaaata ggttgaaagt tttcttttca tataatcacc
      781 aacttgtatc agatttagtt tacttaatta gagtataaca gtgttgtaac ttcaaagagt
      841 atctaaaaga ttacaaatgt tagataaaat catcaataat gtaatttata acacgtagct
      901 ataaactatg caataatata aatggaggta taagtaaatg aaaaagttcc atgttttgct
      961 aacagtttaa acaaatatta ggtagaaaag aatgtatata ggaatctgtg gtaaaattat
     1021 caatttaaaa gtatgattta gtgtgataca gttcttatag gtaatggata acaaatagat
     1081 aaaggaacag tttctttctt agaacatatt ttgttatgac tttaaacaaa gttaatatta
     1141 atgtcaataa tatagtaaaa gaataaaaat catatagtat aataaaaaag agtgtttcta
     1201 aacactcttt tttaatcatt ttcatcttct acatattcaa gtatatcacc tggctgacag
     1261 tctaaagctt tgcaaatttc gtttagagtg gtaaatctaa tagcttttgc ttttccagtt
     1321 tttaaaattg ataaatttgc atttgtaata tctatttttt ctgccaaatc tttaagtgat
     1381 attttccttt ttgccatcat tacatctagg ttaactacta ttgccataac atcacctcta
     1441 tattgttaaa tcattatctt cttttatttt tatagcttta tcaaatgttt ctgcaattac
     1501 aaagcacatt agtgcaaata taaaagagat aaccataagt ggtgagatac cgccactatc
     1561 agttccaaaa attcttatat tattagtatt taaattataa ccatttatac attcaattat
     1621 agtgtttatc aataaacaac atcccattac cttaaacctt tttacatttt caagtacgaa
     1681 tggggaatac ttagtactat taattataaa tatcaagaat aagatgacta taaagtagtc
     1741 aaaaaaatat agtattcttg caattaaagc gattactttg tcagaactaa aatcatataa
     1801 aaacataggt atcatacata agaatattat accagcaact cctaaaagtg ataatagaaa
     1861 atatagaaat actgataata tattactaaa aaattttgta atcataaaat atcatctcct
     1921 ttat
//
LOCUS       DAEOTL010000205         1923 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.210, whole genome shotgun sequence.
ACCESSION   DAEOTL010000205 DAEOTL010000000
VERSION     DAEOTL010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.210"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            31..480
                     /locus_tag="KRH82_003943"
     CDS             31..480
                     /locus_tag="KRH82_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657186.1"
                     /translation="MSYWFDLPIDVAEFEEKLGVGAESGDYRIIEKVLPYADEVHEHT
                     SVYQLNELDFMYRQLSSDMQEEYVSLLTVYENLEALYICRNVITVYPDCKSMIDVARQ
                     KLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEHGIFELPE"
     gene            498..1001
                     /locus_tag="KRH82_003944"
     CDS             498..1001
                     /locus_tag="KRH82_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657187.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            1119..1517
                     /locus_tag="KRH82_003945"
     CDS             1119..1517
                     /locus_tag="KRH82_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657188.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            1495..>1923
                     /locus_tag="KRH82_003946"
     CDS             1495..>1923
                     /locus_tag="KRH82_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HBG8657189.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHE"
BASE COUNT          609 a          362 c          432 g          520 t
ORIGIN      
        1 gaaacgagag gaacaactgg cgaagaaaca atatcatact ggtttgacct gccgatagat
       61 gttgccgagt ttgaagaaaa attaggtgtc ggtgcagaaa gtggggatta ccgcattatc
      121 gaaaaggtac tgccttatgc tgatgaagtc cacgaacaca ccagcgtgta tcagctcaac
      181 gaattagatt ttatgtaccg ccagctttca agtgatatgc aggaagaata tgtatcacta
      241 cttaccgtgt atgagaattt agaagcactt tatatttgca ggaacgtgat taccgtttat
      301 cccgactgca aaagcatgat tgatgttgca aggcaaaagc tgatgaacga cccgacattc
      361 aaacatttat ccgaggactg tcaagaatac tattttgact ttgaagccta tgcttctcac
      421 ttgcaggaac acggaaaatt tttagtaacg gaacacggta tctttgaact gccagagtag
      481 gaaatgaggt ggtgcttatg attgatgata tggcggttta tattgctaat cttggcagat
      541 acaatgaggg atatttagtc ggtgcgtggt tcactttccc tattgacgag gaagatgtaa
      601 aagaaaaaat cggcttgaat gaacagtacg aagaatacgc tgtccatgat accgacaact
      661 ttcctatcga cataggggaa tatgtttcca ttgaagaact caatgaaatg tatgaaatga
      721 tagaggaact tcccgactat atcgtagagt gtctggacga atttatcagc cactatggga
      781 cgctggaaga agtcgtggaa cataaggacg atatttattt ttatcccgat tgtgaaacca
      841 tgacagatgt tgcctactac tacatagacg aattgaacgc acttggggac attccagcta
      901 acttacagaa ctatattgac tatgaagcct acgggcgaga tttggatatg ggtggtcgat
      961 tcattgaaac aagccgaggt atctgtgaga taccatatta acgctggaag atcagcaaca
     1021 agcattgttg ctactgacag cgtatttctc tttaagggac agtctgaaaa tggctgtcct
     1081 tttctctttg aagaacttac gaaaggggct gaaagaactt gaaaaagatt aaaagctaca
     1141 cgggtatctg gaacgtggaa aaagtcttat atgcaatcaa tgactttaac ttaccctttc
     1201 ccgttacctt tacacagatt acatggtttg tgattacgga atttatcatc attctgtttg
     1261 gggatatgcc cccactttcc atgattgagg gagcatttct caaatacttc ggtattcccg
     1321 ttgctctcac ttggtttatg tcgcagaaaa cctttgacgg aaagaagccg tacagctttt
     1381 tgaaatcaca gataacctat gccttgcgac ctaaaatcac ttatgcagga aaagccgtaa
     1441 aactgcataa gcagatattg aatgaaacaa tcacggcagt aaggagtgtg aactatgttc
     1501 ccgataaaat atattgacaa taaccttgtc tggaacaagg acaatgaggt gttcgcctac
     1561 tatgagctga taccgtacaa ctattctttt ctatccgcag agcagaaatt tatcgtgcat
     1621 gacagttttc gacagctaat cgcacagtcc cgtgagggaa aaattcatgc gttgcagatt
     1681 gccacagaaa gctccattag aagtatgcag gagcagtcaa agaaactggt aacaggcaaa
     1741 cttcgtgagg tggcagtcca aaaaatagac gaacagaccg aagcgttagt atcaatgatt
     1801 ggggacaatc aagtggacta ccgctttttt cttggcttta agctcatggt tacggaagaa
     1861 cagctcaatc tgaagaacat caaaaaatcg gcatggctga cgttcaagga atttcttcat
     1921 gaa
//
LOCUS       DAEOTL010000206         1848 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.211, whole genome shotgun sequence.
ACCESSION   DAEOTL010000206 DAEOTL010000000
VERSION     DAEOTL010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.211"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..741)
                     /locus_tag="KRH82_003947"
     CDS             complement(<1..741)
                     /locus_tag="KRH82_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657190.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLEKGLTLSPYNLITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEA"
     gene            complement(808..1422)
                     /locus_tag="KRH82_003948"
     CDS             complement(808..1422)
                     /locus_tag="KRH82_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657191.1"
                     /translation="MSEKLLDLLKIFLEKYLVPTVIAIVFSFIAYYVTPTDNKLLVKF
                     TIWGYAVFLFCVWFLIIELVIWLVQKIQYHNYSKGVEQRNKQRQAEEWQQSLEFLWTD
                     VDNLSSSDYKLLLRFIKNENQPYCSSGTPMGHCLLNSDWVHKTVSKPAKRVLIKSNQR
                     TSSKAIPIPVYETISETYQYILREDIYQMLKYSYEKYGKISHFK"
     gene            complement(1513..>1848)
                     /locus_tag="KRH82_003949"
     CDS             complement(1513..>1848)
                     /locus_tag="KRH82_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8657192.1"
                     /translation="ELKFTAVRDVFLQNEDGTPSTQLKKRIYDLKCSLHGGIIPVSVP
                     PEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAEDIVLKNKGNQNAGNPQN
                     HTPQGQTKK"
BASE COUNT          545 a          394 c          319 g          590 t
ORIGIN      
        1 ggcttcaatg agcgtcagca gaaagtaagt cttaccgcca ccagtcccac cagcaatcag
       61 ggcgtgaggg agtgcgtcat attcccagac aagatttttc atcagtctaa gacagccgtt
      121 ttctgcccgt acttcatcaa tggtaatgcg gtttgctatc atatcataaa gcagggtata
      181 ttcaatataa ccgtcatgca gtgttttgtc ggttagctca caatacaagc cactttccaa
      241 tttatcctct aaccgtaaaa gctggtcttg atatttcccc agcgtaattt cacagcggat
      301 atgaagcagt cccttttcca tttgataata aatctttgga aaccagacga ttttttccct
      361 tgatctgctt tgcaggtcag taaaaaaacc gctgtcttgt acggtatcgg cttcatacca
      421 cttattttcc agtatcattc ttgccagctt ttgacggtgc aggagcttct tgaaactgtc
      481 gtaacagaag cgataataca gaaaagcgac caatgcacaa acaccagtcg ctatcagtat
      541 ggttatcaag ttgtaagggg ataacgtcaa gcctttttcc aacaagctga aatgttccca
      601 atcggtacgc atgagctgtt tgatattcag tagcaggaga accgccacga atacaaacag
      661 aagcgtccct atggaaaagt gatagacaag gtgcttgtcg ctggctctga tacggtgtcc
      721 tttgttccaa atcttacgca taaatcaatc actcctttct gggtacgaaa aaagcagtca
      781 atcctaagac taactgctag ttacgattta tttgaaatgt gaaatctttc cgtatttttc
      841 gtatgaatat ttaagcattt gataaatatc ttctctaaga atatactggt atgtttctga
      901 gattgtttca tacaccggaa taggaattgc ttttgatgaa gtcctttggt tcgattttat
      961 caacactctt tttgctggct tagatactgt tttatgaacc caatccgaat tcaataaaca
     1021 gtgtcccata ggtgtaccag aactgcaata tggttgattt tcattcttaa taaatctaag
     1081 caataattta taatcacttg aagataagtt atccacatct gtccaaagaa attctaaact
     1141 ctgttgccat tcttctgctt gtctctgttt gttacgttgt tccacacctt ttgaataatt
     1201 atgatactgt attttctgta ccaaccatat tactaattcg atgattagaa accatacgca
     1261 gaataggaaa acagcatacc cccaaatagt gaattttacc aataacttat tatccgtagg
     1321 tgtaacgtaa taagctataa aagaaaaaac tattgcaata actgtcggta ctaaatactt
     1381 ttcaagaaat atctttaata aatctaataa cttttcactc atgcatctat gccccttaat
     1441 taaaaaatca cattaaaaat attatacgat ttcttaattg cagaggcaat caaaatatat
     1501 ttgatgaact aattattttt tcgtttgtcc ctgcggtgta tggttctggg gattgcctgc
     1561 gttttgattg cctttattct tcaacacaat atcctctgcc tttacatacc agtccacatc
     1621 tgcacccgta taggtctttc ttgatactgt atcggctacg ggattgacaa gctccacaac
     1681 tgcattgtac ggaaattccc ttaacggtac ttctggcggt acggacacgg ggataattcc
     1741 accatgcaga ctgcacttca aatcatagat acgcttttta agctgagtac tcggtgtccc
     1801 gtcctcattc tgcaagaata catcacgcac cgccgtaaat tttaattc
//
LOCUS       DAEOTL010000207         1832 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEOTL010000207 DAEOTL010000000
VERSION     DAEOTL010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1832
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.212"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            158..648
                     /locus_tag="KRH82_003950"
                     /pseudo
     CDS             158..648
                     /locus_tag="KRH82_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            676..1623
                     /locus_tag="KRH82_003951"
     CDS             676..1623
                     /locus_tag="KRH82_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657193.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQKGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT          828 a          143 c          245 g          616 t
ORIGIN      
        1 cagaaagact tttacttgta aattgaaatt aatgaagtaa aaaaggattc tttcttaaaa
       61 gtaaataaca actagatagt gaataataaa aaatggtaat ttgaaataat ttttatgaat
      121 agtattaata tatagataca gggagattga tgcgattatg tatgaaaata ataaggtaat
      181 atacaacctt gaaagatgtg aaaaactaga aaagactctt tatttatctc aatttaatac
      241 atataaaaat tttaaattag cttctaaaaa aactgtaata aattcattag agacatatgt
      301 ttacaatatg aatattaaca atataagtct tgttgatact atagaatgta tatcattaga
      361 agatgaacaa cttacaggaa agaagttgat tttagttggt gatatagata ttgatgcaat
      421 attagattat gcaggaaata aaagaaatag aaattctagt aaaaaaatac atttaaatta
      481 aaaataccct ttagtacatt tatacaaatg cctagaaaga tagaaaataa agataaaatt
      541 aatttaaagt atcttataca agatattact tcatctattt tagatgataa tttatttatt
      601 agtgttactg caattataag ttatgaaaat agttccaaga tagagtaatc tttaaattat
      661 agaaaggtgg atgcaatgag aataacgaaa actactttta atgatgtatt ttcaaatgat
      721 gcaaatggaa gtattataaa agtagaaaaa tatgttgata aaaaatgtgc atctgtattt
      781 gagattttga cctacactat tattgttaca aatacaagta ggtacaaaac tggaaatata
      841 tttttcaaag attatatttc taaatatata gagtttataa ataatactgt aaaagttaat
      901 ggcattataa aacgtggatt agacccacag aaaggttttt acatagggag aatagatgca
      961 agttgtaaaa aaataatatc ttttaagagt gtagttttac caaattctgc acataggatt
     1021 ataaagaata gtgctaatat atactattat tataagtgta atctagataa attcccaaca
     1081 agaatatcaa tagaaagtaa tagagtttat actaatgtaa ataaaattgt attcaaacaa
     1141 ttgaatataa gtaatacttt aaaagctcct aaaaatctaa gagatatatt aaaagtaaat
     1201 gtaaatagta aaatatttga tgttaaacct atgaaaaatc ttataaacaa aggtagtaat
     1261 ttgaaattat gtaacttgat agtttttggg tgtatagaag ttgaaataga ctatagttgt
     1321 aaaaatagga gtaattttaa aacagtaaat aagtctaatg acattaaaaa agataagtat
     1381 tataaaaatg atatacaaaa taacaatgaa aatataaacg attgtaaaaa gcaaataagt
     1441 tttggtgata ataaggtaaa aaaaataaca aaaacttttg gattttcttg tttcatttgt
     1501 tctccagttg gaattattta tgaagatatg aaaaatataa atataaaaat tgaacataca
     1561 tcaataaatg aattaaatcc agaagaatta tttgtaaata catcactttt attgtattat
     1621 taagtatttt aaagctaaaa cttaaactta ttaaaatagc atttggttaa aggaaaatag
     1681 atattgatat atttatcata gatataaatg attaattaaa caattataaa taataagtat
     1741 agtataatat ttaaaaaata tagatttatg ataaaataag acaaatatgt taaaaaaatg
     1801 ataatcacgg agaactttta ccttcttcaa tt
//
LOCUS       DAEOTL010000208         1799 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.213, whole genome shotgun sequence.
ACCESSION   DAEOTL010000208 DAEOTL010000000
VERSION     DAEOTL010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.213"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..594
                     /locus_tag="KRH82_003952"
     CDS             <1..594
                     /locus_tag="KRH82_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBG8657194.1"
                     /translation="YKFYQSGELIKHREDDREYMGRTLYLGSLKSDVYFCIYEKDYEQ
                     YVKLGTPLEEADIINRFEIRLRNERAYYAVRDLLTYYDAEQTAFSIINQYVRFVDEEP
                     DKRKNDWKLNDRWAWFIGDNRQSLKLTTKPEPYTLDRTLRWVQRQVAPTLKMLKKIDK
                     GNGTDYMETIEQQAKLTEKHEMIIKQQTTPAKDLVES"
     gene            606..740
                     /locus_tag="KRH82_003953"
     CDS             606..740
                     /locus_tag="KRH82_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBG8657195.1"
                     /translation="MWVLLKDFLLVSMGMGIGVVLMCILNIGKEADYEMKQLEESEDN
                     "
     gene            741..962
                     /locus_tag="KRH82_003954"
     CDS             741..962
                     /locus_tag="KRH82_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657196.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            1039..1512
                     /locus_tag="KRH82_003955"
     CDS             1039..1512
                     /locus_tag="KRH82_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8657197.1"
                     /translation="MDYIIREIKKEEYDLLNDFLYNAIYIPDGVEPPPKSIINCPELQ
                     EYVFEFGKRKDDRALVAEVQGNVVGAIWVRIMNDYGHIDNDTPSLAMSVFQKYRGQGI
                     GTSLLQQLLLVEKTSGYSKLSLSVQKNNYAVKMYKKAGFLVVDENSEEYIMTVNL"
     gene            1613..>1799
                     /locus_tag="KRH82_003956"
     CDS             1613..>1799
                     /locus_tag="KRH82_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657198.1"
                     /translation="MSDIFKDMQVKVGCEYISDQPSYKRKVWQEMKRLNLADYEERQL
                     EDFSKYVFGMPYQTLKDV"
BASE COUNT          595 a          272 c          415 g          517 t
ORIGIN      
        1 tataagtttt accagtcggg cgagcttatc aagcacagag aggacgacag agaatatatg
       61 ggacgtaccc tttatcttgg ttcgctgaaa tcagatgtgt atttctgtat ctatgaaaag
      121 gactatgagc agtacgtcaa gctggggaca cctctggaag aagccgacat tatcaaccgt
      181 tttgagatac ggcttcggaa tgaacgagcc tattatgcag tacgagattt gctgacctat
      241 tatgacgcag agcagaccgc cttttctatc atcaaccagt atgtgcggtt tgttgatgaa
      301 gaaccagaca agcgaaaaaa tgactggaaa ctcaatgacc gctgggcgtg gtttatcggc
      361 gataacagac agagcttgaa gctgacgaca aagccagagc cttatacctt agaccgtaca
      421 ttgcggtggg tacaaaggca ggtagcacca accttgaaaa tgctgaaaaa gattgataag
      481 ggaaacggta cagactacat ggaaacaatc gaacagcagg caaagctcac agaaaagcat
      541 gaaatgataa tcaaacagca gacgacccct gcaaaagatt tagtagaaag ttaggagtga
      601 taaaaatgtg ggtattatta aaagacttcc tgctggtatc tatgggaatg ggtatcggtg
      661 tagtcttgat gtgtattttg aatatcggca aagaagctga ctatgaaatg aaacaattag
      721 aagaaagcga ggacaattaa atgaatttcg gacaaaattt gtatcaatgg tttttatcaa
      781 acgcacagag cttagtgctt atggcgattg tggttatcgg tatctactta gggtttaaac
      841 gtgagttttc aaaacttatt ggcttcttgg tagttgcctt gattgctgtc ggtttggtat
      901 tcaatgctgg cggtgtgaaa gatgtactgt tagagctgtt caataagatt attggtgcat
      961 aaaattttat tgtggtactg atatgcgaat gatataatcg gggtgtgaaa aaagataaaa
     1021 tagattagga gttaagctat ggattatatt atacgagaaa taaaaaagga agaatatgat
     1081 ttactcaatg actttttgta taatgcaatt tatattccag acggtgttga gccaccacct
     1141 aaatcaatca ttaactgccc agaattgcaa gaatatgttt ttgaattcgg aaagcgaaaa
     1201 gatgataggg ctttagttgc ggaagttcaa ggaaatgttg ttggtgctat ttgggtacga
     1261 ataatgaacg attacggaca cattgacaat gatacaccgt cccttgctat gtctgttttt
     1321 caaaagtata gaggacaagg gattggaact tcattattgc aacagttatt gttggtggaa
     1381 aaaacttctg gatattcaaa actttcctta tctgttcaaa aaaataatta tgcagtaaag
     1441 atgtataaga aagcaggttt tcttgttgtt gatgaaaata gcgaagaata tattatgact
     1501 gtaaatctat aacagataat ctagtttaca atttcatatc catacacaca aagcagttag
     1561 tcttaggatt gactgctttt ttcttaccta aatttcagat tggagtgatg aaatgagcga
     1621 tatttttaag gatatgcagg taaaggttgg ctgtgaatat atttccgacc agccctctta
     1681 caagcgtaag gtgtggcagg aaatgaaacg gctgaacctt gccgactatg aagaaagaca
     1741 gttagaagat ttttcaaagt atgtgtttgg tatgccgtac cagaccttaa aagatgtga
//
LOCUS       DAEOTL010000209         1705 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEOTL010000209 DAEOTL010000000
VERSION     DAEOTL010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1705
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.214"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(336..647)
                     /locus_tag="KRH82_003957"
     CDS             complement(336..647)
                     /locus_tag="KRH82_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657199.1"
                     /translation="MKKIIKSFTSWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(703..1296)
                     /locus_tag="KRH82_003958"
     CDS             complement(703..1296)
                     /locus_tag="KRH82_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBG8657200.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT          641 a          211 c          214 g          639 t
ORIGIN      
        1 ctaatttaag aaatatagaa agctaatcta aagaagtata ataaactaat ttaggaagta
       61 tagaaagcta atctaaagaa gtataataaa ctaatttagg aagtatagaa aattaatcta
      121 aagaagtata ataaactaat ttaagaaata tagaaaatta atttaaagaa atacaataca
      181 ttaattttta agtaacatta aattaatgta agtaaaataa tgttcatatg aatatttaaa
      241 ggtgcatttt ctgaagctaa gtatatgttg tagagtgtta tgtctctcta tcctgtgaag
      301 tttaatagct caagaaaatg cactatttat gatgattatt ttgttttatt tccaattttg
      361 gaaataacta ttctaattaa atctaaaatt ataccataaa taagaaaaga aagtatagat
      421 gctatgtacc aataaatcga aattgaccct gtaattgttc tacatgggat ttgcatacct
      481 gaatccataa aaacaaaaaa actatcaact ctggaaataa tagacaaaat aggatttaaa
      541 cctattagaa caatactttt tgagtcttga ccaatttgat gcatataaat ctcaaataat
      601 gcaattaaaa aaaaccaaga tgtaaaagat ttaataattt ttttcatcaa aatacctcac
      661 ataatataaa ttctgtttgc actatttgct tactacaact atttatctcc attcagtcac
      721 atcacttaat tgtaatctag gtcttcttga tggttcttca tcaggataac ctaaagatat
      781 tgctgccact aattgactat ctgtatttaa ccattcacat aattcacgat atgcaaagta
      841 tacatcacaa atccaaagac tacctagacc taattccaca gctgtaagcg acatattctg
      901 aattgcagct ccaattgatt gcatatttgc catttcatag aatcgttctt caggggatag
      961 cttttctaaa ggtgatttac ctaatatatt taaaataaaa attgttactg gagcttgttt
     1021 catgatttca actgtgtaat ttgcaccagc gatatgttga cgacttcctg gaagaagccc
     1081 attatcatta atttcatttt gaataccttt gctcatggct ttaagcatag attctttttc
     1141 cttttcagtg atgacaacaa aacgccatgg ttgcctgttt ttagatgaag gtgcatttat
     1201 tccagcttca attattttct ctatagtttc atgtgaaatg ctttgatttt tatattttct
     1261 gatacttcgt ctttttgata tagaatcact tatcatttta agtaacctcc gtttattttt
     1321 tggaaaaatc tatttaattt ttattttcta ttttaattat tttagcatta atcagaaaaa
     1381 aagtcattga ttttagtata caattattaa tgattatatt aagaattgta tcaaaaagta
     1441 tgtgattata ctaagggatt atattaaaca ttatatttaa aattgtatga aaggttgtat
     1501 ttaatattat attgagatat atatatatta ggatttatat atattcagat ttattattat
     1561 attgagtctt atattaaatt aaggactata atttgaaaat aagctataaa aacttaatat
     1621 tgttttgttc agagataaaa aaagaatact ttaggtgatt tttattaaaa attaagagtg
     1681 ataaaattat atactttata aatgt
//
LOCUS       DAEOTL010000210         1560 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.215, whole genome shotgun sequence.
ACCESSION   DAEOTL010000210 DAEOTL010000000
VERSION     DAEOTL010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.215"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            178..378
                     /locus_tag="KRH82_003959"
     CDS             178..378
                     /locus_tag="KRH82_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBG8657201.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            1061..1243
                     /locus_tag="KRH82_003960"
     CDS             1061..1243
                     /locus_tag="KRH82_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBG8657202.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIIF"
     gene            1314..>1560
                     /locus_tag="KRH82_003961"
     CDS             1314..>1560
                     /locus_tag="KRH82_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657203.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKI"
BASE COUNT          610 a          179 c          203 g          568 t
ORIGIN      
        1 attaatatat agcaatgtaa aacgtttaaa tatattttta atattaagaa taattaaaat
       61 gttaactaaa aaatataatt aagtagacat ttctattaat ctatgataca atagtatttg
      121 tggtaataca caattaaatc aagtatatct tgatataggt taataggagt atttttaatg
      181 aataatggaa tagtgaaatg gtttaataat gaaaaaggat tcggttttat atcaatggaa
      241 ggtagagatg atgtgtttgc tcatttctca gctatacaaa cttcaggatt taaatcatta
      301 gaagaaggtc aacaagtaag ctttgatata gttaaaggtg ctagaggtcc tcaagcagaa
      361 aatataacta tattataata tatagatttt tcgggaaaga ctctttttag agtctttttt
      421 tattgttaat atatgtaaga taatcattgg tgaagtaaat aaggtatatt gagtaatgtt
      481 cttgatagtt tatatgctaa tgaatttcaa aaaaataagc actcctataa aaagagtgct
      541 cttaatgtaa atataaacct tcattggtcc agcctaatac cccgtattct ccaagttcta
      601 actatttttt atatacatta tcactttcat ccatatctaa cacaattatt tcttctttag
      661 aatcaatttg taaaatatga ggactgtgtg ttgtgacaat tatttgtgtt tttaggagaa
      721 ttgtttttaa tgtaataaaa attttacata ccacatagtt gatataaaac gcccagattt
      781 tctacaactt ccatatttct aaacattttt acataccaca tagttgatat aaaacccaaa
      841 ataaacttag catctccaat gtttacacat atacaatgct cttaaaattg cagtgaacgc
      901 gcaatagtgc aattgataat acttatcata tattctcaat accttatatt tcaactgcta
      961 aacctcaatt tatcacaaat atcgctcact gcaaaatttc tatattttta ttatatcata
     1021 gcatataatt aatattttca attaattttt acatttaatt atgtttaaat tctataataa
     1081 tgcaacttta atgtttcttt ctggaactaa tataaaaact atttcagaaa gattaggtca
     1141 tgcagatata aaaataacta tgaatagcta ctctcagttt ttagaagaga tggacagaga
     1201 agcatttgaa aatttgagca aaatactatt tattatattt taaagaagat gacttattca
     1261 atatttgatg ctagaatata attaataaaa atttaattat aggtgattgt attatgaata
     1321 ttattaaaag cataacttta ctcttaacat tattaattgt gatattaatg acaggctgtt
     1381 ccccaagaga aagtgctagt gaagttgcaa aaaaatatat tgataagatg aactctggtg
     1441 actatgaaac agcatatagt ttattaagta aagatagtaa aaaaaaaatt agtatagaaa
     1501 atcttgaaga atttcaaaat attttagtta gtacaaaaag aataattagt tataaaatag
//
LOCUS       DAEOTL010000211         1479 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEOTL010000211 DAEOTL010000000
VERSION     DAEOTL010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1479
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.216"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            44..>1479
                     /gene="cls"
                     /locus_tag="KRH82_003962"
     CDS             44..>1479
                     /gene="cls"
                     /locus_tag="KRH82_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBG8657204.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTY"
BASE COUNT          560 a          180 c          233 g          506 t
ORIGIN      
        1 atataattac ttattttaat aaatatttga aggagggaat tttatgtttg atatatcatt
       61 tttcgaaatg tcaatatatg aaatagcagt tactacaata tatataatta atttcatggt
      121 tatactaaac cttatcttta gagaaaaaag aaacataaat acaactttaa catggcttct
      181 tatattagta ttgattcctg ctcttggatt catactttat atagcttttg gcagaaatat
      241 ttcaaaaaac aatatgttta gattgaaaga aaaggatgat aagataatca aaagtaatat
      301 actagatact caggttaaac tccaatctac atctgaaatt gattcagata tacatcaaca
      361 taaggatatg atttatgcat tggctaattc aaataatgct cattatacca ataataacga
      421 tgtgtggatt tatgctgaat ctagtcaatt ttttaacagt cttcttgaag aacttaaaaa
      481 agctaaaaaa tatataaaca tacaatttta cattttcaaa gatgacaaaa tcggaactga
      541 aataatagac attcttatag acaaagctaa agaaggtgtt gaagtaagac ttttatttga
      601 tgcagttggt ggtagaacac taaaaaatag tacactttcc agacttaaag aaagtggtgt
      661 taaagttgga agcttcttcc catcattctt gaaaattgta aactttaact taaactatag
      721 aaatcaccga aaaattgttg tcattgatgg taaggtagga tttgtaggtg gatataatgt
      781 tggtgatgaa tatttaggta gaaatccaaa atttggtcta tggagagata cacatactaa
      841 gcttactggt gattgcgtaa ttgacctaaa tatgagattc atccttgatt ggagatatac
      901 aactaaagaa gatttagatt tagaaaagta ctttatagaa gaagatacaa attctaatca
      961 tccttctgaa aatattggga ttcagatagt atcaagtggt ccagatatat cagaacttga
     1021 tgagattaaa tatggttacc ttaaaatgat tcagaaagct agaaagtata tatacataca
     1081 gagtccttat ttaatacttg actcaacttt tatagatact ttaaaaatag cttgtttatc
     1141 tggtgttgat gtgagagtga tgattccttc taaacctgac catccctttg tatactgggc
     1201 atcatattca tatgctggag aacttttaaa gtttggagct aaaatctata cttatggtca
     1261 aaatgcattt ttacatgcta agacaatagt tatagatgac tctatatgct ctataggaac
     1321 agctaatatg gatatcagaa gttttgagct taatttcgaa gttaatgcat ttatgtactc
     1381 ttcaaaaaaa gcattggaac aaagaattat atttgaaaat gatattttaa attctaagga
     1441 aataacatta gatatatata attctaggtc tacttatat
//
LOCUS       DAEOTL010000212         1476 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.217, whole genome shotgun sequence.
ACCESSION   DAEOTL010000212 DAEOTL010000000
VERSION     DAEOTL010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.217"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(346..837)
                     /locus_tag="KRH82_003963"
     CDS             complement(346..837)
                     /locus_tag="KRH82_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBG8657205.1"
                     /translation="MGMIGCYTKISEENVFKLQQSEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
BASE COUNT          571 a          185 c          129 g          591 t
ORIGIN      
        1 atgaagttat aatttaatat atatttattt tatttgtgag tctattttta tatataatga
       61 aaaatgtgat aagtatccaa aagaattact ggatataata agatagggta tttagccttt
      121 taagataaat aaaaatatct gcaactatat attgcaaaaa tttaaaacta atttatatat
      181 gctaatataa atatttataa agacataaga caaatttacc tacagattta aatttaactt
      241 atatatttta aaaggctaat ataatatgta ttttcttcta tacaatcaaa aggcttcata
      301 tctaagatat gtgatgacac taatattcac aatttttagt aattatcaca ttataaaaaa
      361 tattacagct agtccatcat tagatgcttc ttgtataaac tttttaagct caattagatt
      421 tgcccataca tattcaaaaa aatcatcttc actctcatca ttcataacag gataaatatt
      481 attttctaac atctcattaa tattaaatct ttttctaaat gcttgttctt ccaaactgtt
      541 cattgctttt gatagttttt ttacatcatt tgctgtaatc aacatgacag gaaattctcc
      601 atcaatttcc ataagtatgt ttccacttag tactaatttg ctaaatatat tatcatcatc
      661 tccaccaaaa ggacaacctg tcaaagtaaa gtgaatggca tgccatgctt tatcaatatt
      721 gatagtacta ttttcgttgg catcttcaaa aacaaaatct tgtaaatttt cttctgattg
      781 ctgtaattta aaaacattct cttcacttat tttagtataa catcctatca tccccataat
      841 tacattcctc ctaagtagcg tttttttaat tgtaacttat aattaaactt agttacaata
      901 aaatatattg agaaaagtat tatttcatct taaatttaaa tacctatatt atcaactaaa
      961 attctgtgtt tatagcgtaa gtattattat tttttcctaa aaattaaatg aatcagaagt
     1021 tctataggca atattgacta taaataagga ctattacttt taaaaaaaat ttaagaaatt
     1081 atactgtaga atcatgctct acttattagc ttcaaataaa aaataaatca tgttctcaaa
     1141 ttaaataata aataacaata aatttaaatt ttaaactata agagtttctg aagtgttaat
     1201 aagcatacca ataattatat gtgtaagaat ttgatttaat agatataaat aatttttaca
     1261 ttaattataa atatattaac ctattgttat aaattctaaa aaagaaaagt tatcttaaat
     1321 aaaaaataag tgtatcttaa attttaaatg atacacttat ttttatattg aaattatatt
     1381 ttttaatatc tattcttaat taggtatttt taaattatct gtttacatta aatatttctt
     1441 aattacttat ctttcagcta gctttttcta ttaaat
//
LOCUS       DAEOTL010000213         1458 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.218, whole genome shotgun sequence.
ACCESSION   DAEOTL010000213 DAEOTL010000000
VERSION     DAEOTL010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.218"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..947
                     /locus_tag="KRH82_003964"
     CDS             <1..947
                     /locus_tag="KRH82_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657206.1"
                     /translation="EITLGKYQDQLLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDM
                     IANRITIDEVRAENGCLKLMKNLVWEYDALPHALIAGGTGGGKTYFLLTLIEALLHTN
                     AVLYILDPKNADLADLGTVMENVYHTKEKMIDCVNAFYEGMVQRSEEMKRHPNYKTGE
                     NYAYLGLPPCFLIFDEYVAFFEMLGTKESVGLLSQLKKIVMLGRQAGYFLIVACQRPD
                     AKYFSDGIRDNFNFRVGLGRISELGYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISE
                     FYTPLVPKGHDFLQTIGSLAQARQDGTATCEAKGDGTD"
     gene            1131..>1458
                     /locus_tag="KRH82_003965"
     CDS             1131..>1458
                     /locus_tag="KRH82_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8657207.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSY"
BASE COUNT          445 a          282 c          362 g          369 t
ORIGIN      
        1 gtgaaattac gctgggaaaa tatcaagacc agcttttacg gttagaggat aaattggaaa
       61 gtggattata ttgtgagctg accgacaaga ccttacatga cggttatatc gaatataccc
      121 tgctttatga tatgatagcg aaccgcatta ctattgatga agtacgggca gaaaatggct
      181 gtcttaaatt gatgaaaaat cttgtctggg aatatgacgc actccctcac gctctgattg
      241 ctggtgggac tggtggcggt aaaacctatt ttctgctgac gctcattgaa gccttactgc
      301 ataccaacgc tgtcctttac atcttagacc cgaaaaatgc ggacttagca gacttaggga
      361 cagttatgga aaatgtgtat cacaccaaag aaaaaatgat tgattgcgtc aatgcctttt
      421 atgagggtat ggtacagcga agtgaggaaa tgaagcgaca cccgaactat aagacgggcg
      481 aaaactacgc ttatctggga ctgccaccct gctttcttat ctttgatgaa tatgtggcgt
      541 tttttgaaat gctggggaca aaagaaagcg tgggcttact tagccagtta aagaaaatcg
      601 ttatgttagg acggcaagca ggatatttcc ttatcgttgc ctgccagcgt ccagacgcaa
      661 agtatttctc ggacggtatc agagataact tcaatttccg cgtgggactt gggcgtatca
      721 gcgaattagg ttacggtatg ctgtttggtt cagatgtgaa aaagcagttt ttccagaagc
      781 gtatcaaggg gcgtggctat tgtgatgtgg gaacaagcgt tatcagcgaa ttttacacgc
      841 ctttagtccc gaaaggacat gactttttgc agactatcgg ctctcttgca caagcaaggc
      901 aggacgggac ggcgacgtgc gaagcgaaag gcgacggcac ggactagccg ttgctggtgt
      961 ggcgtaagcc acgccagcag gtaaaacccc tcggtatcta acagaggggt acgtttgcaa
     1021 atagacaata gacgaaaaac ataggaaaca taaggcttct ggcatgattt cccagtaaaa
     1081 atcggctgtg aagtcgcctt aaaaaacttc acacttgaca gattgggggt atggttctga
     1141 atgaagaaca atggataaaa gaattacggg agaaacggat tgcttacggt atctcacaag
     1201 gcaggctggc ggtggcttct ggtatcacaa gggaatatct caacaagata gaaagcggaa
     1261 aaatgaagcc gtcaaaggaa cttctggaaa ctctgcataa agaactggca aggttcaatc
     1321 cagaagcacc gcttaccatg ctgtttgatt atgtgaaaat tcgttttccc acgctggata
     1381 tacagcacat catcaaagat atattaaaac tgaatatcaa ctatatgctc catgaagatt
     1441 acggacatta cagttata
//
LOCUS       DAEOTL010000214         1440 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.219, whole genome shotgun sequence.
ACCESSION   DAEOTL010000214 DAEOTL010000000
VERSION     DAEOTL010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.219"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(48..485)
                     /locus_tag="KRH82_003966"
     CDS             complement(48..485)
                     /locus_tag="KRH82_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBG8657208.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVYDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            complement(742..891)
                     /locus_tag="KRH82_003967"
     CDS             complement(742..891)
                     /locus_tag="KRH82_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBG8657209.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            complement(904..1134)
                     /locus_tag="KRH82_003968"
     CDS             complement(904..1134)
                     /locus_tag="KRH82_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBG8657210.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
BASE COUNT          480 a          182 c          167 g          611 t
ORIGIN      
        1 caataaattt gcaattagtg atattaataa attactttag atttttatta aatgtttagc
       61 ttttctttaa tattttttat ataacgacga tttataataa ctttttcgtt gttttttaaa
      121 gtagcttgca tgcgattatg tgatattact tttatacttt ttatgtagtc catatttaaa
      181 atcatggatt tagatattcg tgagaaggat gtattagcta ataattttga taatttatat
      241 atttttaaat caatttcaaa tacatcatct tcataataag caaatgtttt atttccaact
      301 gtctcaaagt ataaaatatc atagacattg agtttataaa tctctcctga ttttttacct
      361 tttatatcaa gtaacggtgt actcaataat gaaattattt tttcaatgtt attatctaga
      421 gcagaacatt ttatggttat ttcaatatca tcacaattaa taccttgttc gacatgtatt
      481 ttcattaatc atcacctcat tttattactg tcattagaat agcattatat cttattgagt
      541 ccaactagat gcgttctaaa tttcaaatta agcatagtga aattcaaaaa taaaacagtg
      601 aaattcaaat ttgaggtggt aaaattcaaa aaaatactat ggatatttgg ataaattatc
      661 caaatatcct agcattttac atagaatatg cctaattatt ttacaaatag acctatttta
      721 tgacttacat atattgtcaa attacttctt aaatatcaaa atatttttgg ataatgtatc
      781 aatactgttt gataaagtat ttaatttacc ctcaattcta accaataagt acatggatag
      841 agctatagga aaaccaacat tggttattaa cagttgtaaa ctatcatcca taaaattagc
      901 cccctattct ataactaagt cataaggagt ggtatttgtt tccacaacct tggcttcaac
      961 cacagaagct aggtcaaatc ctccaaccga aaaaatattt ttagatacta tcaaatccat
     1021 gacagatttt atattttctt cagttaaatc atcctttgga ttttctatag aaaaagaaac
     1081 ttgtttatcc tttacatttt taaagctcat gactaatttt ttcttaattt ccatataatt
     1141 acctccgata taataattta tattttaatt gtttgcttgt taatattggt attttaattg
     1201 tcaatattag tgttttgctt gttagtatta atatttcaat tgtcaatatt aatgttttgc
     1261 ttgttagtat taatatttca attgtcaata ttagtgtttt gtttgttagt atcagtgttt
     1321 caattgtcaa tattagtgtt ttgcttgtta gtattgatat ttcaattgtc aatattagtg
     1381 ttttgcttgt tagtattgat atttcaattg tcaatattaa tgttttgctt gttagtatta
//
LOCUS       DAEOTL010000215         1424 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.220, whole genome shotgun sequence.
ACCESSION   DAEOTL010000215 DAEOTL010000000
VERSION     DAEOTL010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.220"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..1097)
                     /gene="bclA1"
                     /locus_tag="KRH82_003969"
     CDS             complement(<1..1097)
                     /gene="bclA1"
                     /locus_tag="KRH82_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBG8657211.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECLPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGNTGV
                     TGNTGVTGSIGPTGATGPTGVTGEIGPTGVTGPTGVTGEIGPTGATGATGVTGSIGPT
                     GATGPTGATGVTGEIGPTGEIGPTGTTGPTGV"
BASE COUNT          357 a          300 c          189 g          578 t
ORIGIN      
        1 actcctgttg ggcctgttgt tcccgttggt cctatttctc ctgttggccc tatttctcct
       61 gtcactcctg tcgctcctgt tggacctgtt gctcctgttg gtcctatact tcctgtcact
      121 cctgtcgctc ctgttgctcc cgttggtcct atttctcctg tcactcctgt tgggcctgtt
      181 actcccgttg gtcctatttc tcctgtcact cctgttgggc ctgttgctcc cgttggtcct
      241 atacttcctg tcactcccgt atttcctgtc actcccgtat ttcctgtcac tcccgtattt
      301 cctgtcggac ctgttactcc tgttggtcct atacttcctg tcgctcctgt acttccggtt
      361 gggcctgtta ctcccgttgg ccctatactt cctgttgctc ctgtatttcc ggttgggcct
      421 gttggtccta tgcttcctgt cgctcctgta cttccggttg ggcctgttac tcccgttggt
      481 cctgtacttc ctgtcgctcc tcttggtccc attggacctg taattctaat tggaagacac
      541 tcacatttag gataacaatt atctataatt ctatcttcaa atgttacaag tatatacggt
      601 ttgttacaac ctctactaga tgtaaattca agaatctgat aagggtaatt taaagataaa
      661 gctaacccat aattaggata tttattcatt gcccatgctt ttatagttcc tgtaatattt
      721 aaacaaatat agttggatgt atcacttatc ccaactggta aatatcccct aatattttcc
      781 atagacactc tatcattcca tgttatagtt cgtaaattat aatattcact tattctttta
      841 atttcaatat ctactttttc tttaaaaata tgattcttat ttgaatcaat atgaataaat
      901 aactctgctt ttaatatact tttgtctttt aatatatctg gtattctcac tttaaaaaaa
      961 gtaatcaact tttcttttac aaaactattt gaacatttac ttcctattaa gcaataatct
     1021 aaattactaa agtttttatc tggatatttt ttagatataa aagtatcatc atttaaataa
     1081 agtataatat ttctcattta taatccctcc attttgggtc tatatcatac tatgtttaaa
     1141 atacatgctt agttacaata taattaaaat ttatagtatt aaatttttat ataataatgc
     1201 tgatttctac aaaaaaagaa catgtcatta gaaatttcta atagcatgtt ctttttcatt
     1261 attatatatt acactttaaa ttattccttg actggcttag ctggtgtaaa ctaaaccagt
     1321 ctttctaaaa tattaagcac ttttttctta ttatgttttt taggatttat tgtctatatt
     1381 attgtaaacc aaagttataa aattgtaaat agaatatatt acca
//
LOCUS       DAEOTL010000216         1377 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEOTL010000216 DAEOTL010000000
VERSION     DAEOTL010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.221"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            1..542
                     /locus_tag="KRH82_003970"
                     /pseudo
     CDS             1..542
                     /locus_tag="KRH82_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(766..930)
                     /locus_tag="KRH82_003971"
     CDS             complement(766..930)
                     /locus_tag="KRH82_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657212.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
BASE COUNT          574 a          175 c          115 g          513 t
ORIGIN      
        1 gttaaattag aagaaacttt taatataaaa aaccttcttt ataaaaaaga tgattctcta
       61 aaagtaaata gatattttgt agttgaaaat aacaaataca agctattatt gtatgaaagt
      121 ttcaaaaaag aatttggtat taatagtatg gaccttgctc aacttaagct taatgatttt
      181 ggactaaaat actttaaaga agttgacctt atactaaaaa agctattgct attaatccta
      241 ctgattcaaa gctttattat gcccaagcat gtaattatat gaattttgat ggatttcctg
      301 gttattcaga tacaacatat aatgctttag attcaattaa taaatcttta aagtatttag
      361 ataaaaatga ttctgactac aaaaaaaatg caagtaatat atataactta aaaggagtta
      421 ttcttatgtt tcacaaaaga tttgatgaag cacaacaata tttaaataaa gccttatact
      481 ttaacaaaga taatgaagac ccaaaatata atctaaatac aataaaaaaa catctaaact
      541 agatatttaa tttttgaatt tataaaatat ttttttatgt ataattcagc actgaatcat
      601 aatctctact aaactaatta caagtttaaa ttataaagac ttatttctat ataaatatta
      661 ctctataaca ataagtttct tatttaaatt ttaaaatatt atctaaaaat cataaaaaag
      721 aaggtataaa gagctaccct caagctcaat ataccttata aatatctaaa cttcattttt
      781 tactaatttt tctatatctt tgataatatg ttctttagat ttttttccag ctatggcatc
      841 aaaaattgca acagcctttt tctctccaaa cttttctgct acatcattaa agtctaaaaa
      901 tctaacactt tcttttggtt taccaaacat ataacacctc tcatacattt ttatatattt
      961 attataactt ctatagactt atttttcacc aataaacgtt agacaaatta gtccctttat
     1021 ttttttaaac tagctttacc ttcaaaattc ttaacaaaaa cagtttattc tactctataa
     1081 ataaaaatag acaatttaat ttgtaggaaa ctgataatag aatacagtaa ataaaacttt
     1141 gtttaatcta tctgaaaaag ttatctatta aaactgctat gaatttataa agaatattct
     1201 agttcataaa aatacaaata tgtaaatata atcaccttaa tattaattta tttaaaataa
     1261 aaaatgtata aaagatttaa taatgacaat atactattct caatacaatc tatgatgtaa
     1321 ataatttaaa actactatat tatttaaaaa tttatattta tatatgcaat tctaaaa
//
LOCUS       DAEOTL010000217         1363 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.222, whole genome shotgun sequence.
ACCESSION   DAEOTL010000217 DAEOTL010000000
VERSION     DAEOTL010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.222"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(476..865)
                     /locus_tag="KRH82_003972"
     CDS             complement(476..865)
                     /locus_tag="KRH82_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBG8657213.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          448 a          223 c           90 g          602 t
ORIGIN      
        1 acttttgttt ctacctcttc agtatcttat atcaatcttt tattttttca atatcttctg
       61 ttaacacttt tatctctatc tctttaatat cttatattaa tcctttattt ttattttttc
      121 aatatcatca ttaattccta tttattttat catcttaaat acgaaaacac tgtgtcatat
      181 ttgcaaaata tatattatca tctatattaa agcttcacaa tttatattta aaaattctct
      241 ttaattacac tacctctatt taaaaagcta ccttaattat acttataagt aaaggtagct
      301 ttttaaattt aattaaatag aatatccact attaatttat atttaattta tttagattca
      361 cattatagta tcataatcca cttataatca tttgtcatat tacttaagta gactaatata
      421 ttacataaat acacttacat acactttata ttgatgctat aagaaatacg tttgcttata
      481 cgtctttctc ctcttctttt agatttttta tccactcttc aataagtaaa atatcatctt
      541 tgctcaaatt aatattttca tgtaatgaca acaataaact ttttatagaa gaatcatgaa
      601 tatttctaaa aaaatctctt gtctcaactc ctatgtattc cttttcttta attaaaactt
      661 cataatgcgt atatttatct atcttttgag aatttagaaa tctttttact actaatctag
      721 ataaaagagt caaagttgtc gtttgtttcc attgatattt ttgctccatt cctaaaacaa
      781 tatctctaga tgttactttg gaatctgatt tccatataaa tttcattatc tttaattctg
      841 attgtggcaa cttttttata gtcatgataa aaccttgcta ctcagaatat agacaagcaa
      901 tatccataat aaaatttttc gattaaatac atcttatacg gatttatata agctcagact
      961 tataagatat ttttcaatct taatcctaaa tttagctatt tgtacacggt aaatatatat
     1021 aaataatgtc aaaattctct tgtattatat tgcttaattt tatgaaatat tttgtactca
     1081 gctatctatt ttggatactt gtccagtagc tctcctttct tttaaactct ttgattttaa
     1141 atatttgtat ttcagtaaat cctacttcct aaatttttta tttactacaa cttattactg
     1201 aacttcctac ttcctaaact ttttatttac tacaacttat tactgaactt ctcacttact
     1261 aaatttctta cttactataa attataacta aacttctcac ttactaaatt tcttacttac
     1321 tataaattac tactaaactt cctactttct aaatttctta ctt
//
LOCUS       DAEOTL010000218         1341 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.223, whole genome shotgun sequence.
ACCESSION   DAEOTL010000218 DAEOTL010000000
VERSION     DAEOTL010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1341
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.223"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..586
                     /locus_tag="KRH82_003973"
     CDS             <1..586
                     /locus_tag="KRH82_003973"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBG8657214.1"
                     /translation="YGTMAQEAIEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIY
                     DECPITVVVEADEADCYYKSAEAGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNH
                     AAAFVSAPDWVSAKGMRTLGNPLNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDL
                     KLDENSRILLISTEGDTDPDKYRSIVWDGEYPSI"
     gene            713..>1341
                     /locus_tag="KRH82_003974"
     CDS             713..>1341
                     /locus_tag="KRH82_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBG8657215.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMASVIQ"
BASE COUNT          510 a          152 c          300 g          379 t
ORIGIN      
        1 atatggaact atggctcaag aagctataga gcaattaaaa gaatatggag tagatagacc
       61 aacacacgta tttgttcaag caggagttgg ttcacttgct ggtgcagttc aagggtatgt
      121 tgcttcaata tatgatgaat gcccaataac agtagtagta gaggctgacg aagctgattg
      181 ttactataaa tcagcagaag ctggagatgg aaaaccaaga tttgttggag gagatatgcc
      241 aactataatg gcagggcttg cttgtggaga accaaatact ataggatttg aagtattaaa
      301 aaatcatgca gcagcatttg tttcagcacc agactgggtt tctgctaaag gtatgagaac
      361 attaggtaat cctttaaatg gtgatgaaaa ggtaatttct ggagaatctg gagcagttac
      421 aactggtctt ttagtagcag ctatggaaag agaagattta gcagatttaa gaaaagattt
      481 aaaattagat gaaaattcaa gaatactttt aataagcaca gaaggagata ctgaccctga
      541 caaatataga agtatagttt gggatggaga atatccaagt atataaggaa ttactaaaat
      601 gcaattatta gatattggtt tacatattta gaagatatat aagttctaaa atttagaaaa
      661 tatataagta tataaaatac atacattata aaaaatctag ggggataatg aaatgttaaa
      721 cgaacaaaga aaacaagaag taactgaaat atgccaaaaa ttaattcaaa atcctagttc
      781 ttctggaaat gaagaaggtg ttgtaaaagc aatagaagag tcttttgaaa aattaggttt
      841 tgatagttgg tcaagagata gatatggaaa tatagtagga tgtataaaag gtaacaagcc
      901 aggtaagaaa atcttatttg atggacatat agatacagtt ccagttccag atgcaagtaa
      961 atggagtgtt cctccttttg aaggaaaaat agttgatgga aagatatatg gtagaggaac
     1021 ttctgacatg aaaggtcaat atactgcaat gatgtctgct gtagcgtatt ttgctaaaga
     1081 cactaataga gattttgctg gagaactata tgtagcaggt gttgttcatg aagaaatatt
     1141 tgaaggtgtt tcagctagag agataagtaa ggctgttcaa cctgactatg ttgtaatagg
     1201 tgagtcttca gagttaaact taaagattgg tcagagaggt agaggagaaa tagtagtaga
     1261 aacttttggt aaaccagctc actctgctaa tccagaaaaa ggtgtaaatg cagtttataa
     1321 aatggctagt gtaatccaaa a
//
LOCUS       DAEOTL010000219         1298 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEOTL010000219 DAEOTL010000000
VERSION     DAEOTL010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.224"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..187)
                     /locus_tag="KRH82_003975"
     CDS             complement(<1..187)
                     /locus_tag="KRH82_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657216.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     EDFSKYVFGMSYQTIKDV"
     gene            complement(270..911)
                     /locus_tag="KRH82_003976"
     CDS             complement(270..911)
                     /locus_tag="KRH82_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBG8657217.1"
                     /translation="MEYKYTKIDLEKWNRGKLFQSYIDDMRIVMSLTVDIDVTNLIEF
                     SKSHDLKFYPAMIWVVSKVVNEHDEFKYSWDNKGNLIKWDYISPSYAEFHKEDENFTK
                     MVTDFSDSIFEFHERFMLDREKHKMERAFVANQPLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELERERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSIS"
     gene            complement(1119..1280)
                     /locus_tag="KRH82_003977"
     CDS             complement(1119..1280)
                     /locus_tag="KRH82_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657218.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
BASE COUNT          433 a          265 c          167 g          433 t
ORIGIN      
        1 tcacatcttt tatggtctgg tacgacatac caaacacata ctttgaaaaa tcttctaact
       61 gtttttcttc ataatcggca gggttcagtc gtttcatttc atgccacact ttacgcttgt
      121 aagagggcag gtcggaaatg tattcacagc cgacttttgc ctgcatatcc ttaaaaatat
      181 cgttcatttc atcactccaa tctgaaattt tggcaagaaa aaagcagtca atcctaagac
      241 taactgcttt gtgtatatct ggtattagat tatgaaattg agtttatcaa ttcttgtact
      301 tcattaaaaa atctggataa atgaaaacca tctgcaacgg catgatgtat attcattgta
      361 agaggcatta tatatctttc tcgctctaat tcgtatttac cccaagtaat aactggtgca
      421 agaaatttcc cttcgtcaaa aacatgaaca tcaaaatgat tgtattttac ccatggcaaa
      481 caagatacat caaaaaagtt caaaggttga tttgctacga atgcacgttc cattttatgt
      541 ttctctctat ctaacataaa tcgttcatga aattcaaata tgctatcaga aaaatctgta
      601 accatttttg tgaaattctc atcttcttta tgaaattcag cataggacgg ggaaatatag
      661 tcccatttaa ttaaattacc tttattgtcc caactatatt taaactcatc atgttcatta
      721 acgacctttg aaacaaccca tatcatagct ggataaaatt tcaaatcatg gctttttgaa
      781 aattcaatta gatttgttac atcaatatct acggttaagc tcataacgat acgcatatca
      841 tcaatgtaac tttgaaacaa tttacctcta ttccattttt ctaaatcaat ttttgtatat
      901 ttatattcca tgtccattct cctttacatt ttgaaattca gtaaaatgca aggctctctg
      961 gataacattt cactccatgc aagtctattc cattaagcct tgtatggaga taatacaata
     1021 cacaatttca taatatccct ccttatccaa taaaccttag tttattgttt tcatactcag
     1081 attataccat tcatatatag gctctacaat aaaaatcatt atgcaccaat aatcttattg
     1141 aacagctcta acagtacatc tttcacaccg ccagcgttga atactaagcc gacagcaata
     1201 agggcaacta ccaagaagcc aataagtttt gaaaactcac gcttgaaccc taagtagata
     1261 ccgataacca caatcgccat aagcactaag ctctgtgc
//
LOCUS       DAEOTL010000220         1257 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.225, whole genome shotgun sequence.
ACCESSION   DAEOTL010000220 DAEOTL010000000
VERSION     DAEOTL010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.225"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            166..1059
                     /locus_tag="KRH82_003978"
     CDS             166..1059
                     /locus_tag="KRH82_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBG8657219.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
BASE COUNT          533 a          118 c          186 g          420 t
ORIGIN      
        1 tttaactatt ttgtgtgata gaaaactata tattataaca atagtagtgc ttttaattaa
       61 atatatttca taaatcttca taaaatcttc aaaatttcgt aaagaatatg tcacaaaagt
      121 aaggtatatt atattcagca gatagtataa gggaggacaa tatttatgaa gaataaaaaa
      181 ttcattgtta taatactgat aatatcaatt ttaataggtg tattagtgaa ggaatattca
      241 tctagagaga taaaaaagga tgatataaat gtcagtaagt atataaaata tgctgattta
      301 gcaagtaaaa ataatgcaca agttaactgg aagtatgtag cttccattgt tgctgtgtta
      361 aataaaaata acttaaaaaa cgttaaggat tcacagatac aagaagtatc agatttattt
      421 gttaagaatt tttctaaaaa taataaaata aataagttaa gtgatatttt ggatgagtta
      481 gaatttagta atagacaaaa aagattggtt gataattata tagacaatct taaggattat
      541 ggtataaaac cagaaagatt gaagtctgat acaaaatata tgaagtttat tgatgaaatt
      601 aaaacagaag caatacaaaa ttataaggat tataaaatac ttccatctat aactattgca
      661 caagctataa tagaatctag ctggggcaag tcaactttgg caaaacaata taacaatcta
      721 tttggtataa aggctgacgc ttattggaaa ggtaagtcag tgactttaga aacgaaagaa
      781 catttagata caattataga tgataaattt agaatatatg atgataaaaa tgaatctata
      841 aaagaccatg caaaattttt agccacaaat aaaaggtata aaaacaatgg tgtatttgat
      901 gcaaaaacgt atatatatca agctaaagca ttagaaaagg caggttatag tactgcgaag
      961 gatgaaaatg gcaatagtat atatgcagct cgtctaatag aattaattca acagtataat
     1021 cttcaattaa tagacagtga aattcaaagt gaaatgtaac tttgattaaa tttttattga
     1081 taaggctatg atttttaaaa tcatagcctt attttgacat gtttttactt ttaattatta
     1141 aatcgatatc attatctttc aaaatttact ttatactgta aattaaatta tttaagttaa
     1201 aacttggaat tatttataaa aggattattt actttatcta aattctgcac ttaaaga
//
LOCUS       DAEOTL010000221         1221 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.226, whole genome shotgun sequence.
ACCESSION   DAEOTL010000221 DAEOTL010000000
VERSION     DAEOTL010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.226"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(317..823)
                     /locus_tag="KRH82_003979"
     CDS             complement(317..823)
                     /locus_tag="KRH82_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBG8657220.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          440 a          173 c          107 g          501 t
ORIGIN      
        1 aattaacttt gaaattattt acattaaaat aaatcaaata caaatgccat aaattaagtg
       61 tttctagtta gcataaaaat acttataaag tatactcaag tatttcaaat aaatactttt
      121 attcaaataa atctctactt atataagtgc ttatataaat aaaaagatga actatagtaa
      181 atatagttca tcttttttat aatagtattt atttaaaatt aatatttatt tagttactag
      241 catctactta gatatcagat aagaaagcac agtcatttac ttataataag ttcttttcat
      301 atatttttta ttataattat tcttttacaa gaacttttat aatttctgaa atgtacatag
      361 tatggtaatc tttctctgga taccattttt tatcattttc tttagcatca aagttttctg
      421 gtggcatatt accatgatat agctttttac atactataat catattagct tcttcaaaag
      481 ctaccgtatc atccacaaaa tatggtgtaa gtcctgcttt ttctatttta tttatatctc
      541 taccagaaat agtgccacaa atatttaaag cttctctata cgtttcatca aagaaggcaa
      601 ctgtaaatgt atcattacta tctacaaatt cttttgtata tctctgtggt cttatgtaag
      661 ttgtaacaac atttttaccc caatagactc caacaccacc ccagctagca gtcattgtgt
      721 taaacttttc tgaatcacca gctgttataa gtaaccattc tttgccaatc ttagtaaatg
      781 gattaaactg taattcctca atttttactt ctctaaaacc catgacttca tcctaccctt
      841 cattttttaa ttatataaat taattgttaa aaatttgaat atatgtactc ttataatact
      901 gacttttgat tgtcctacat aattcatgta aattataata caacaaatca attactttcg
      961 caataagtag ttttcatatt ttataagtgt aaaatataga taaaatatat tgattataaa
     1021 gtatataata tatttttaaa cctaaagcaa tatacaataa aaaaatgtag aaagtaagta
     1081 tctctctaca ttttttattg tatattattt ttatattaat ttaattttat cttgattcag
     1141 ttttataaaa aattgttata attgtcaagt tctactctat tatttataat ttcttatatc
     1201 ttattaacaa catttaagtt a
//
LOCUS       DAEOTL010000222         1190 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.227, whole genome shotgun sequence.
ACCESSION   DAEOTL010000222 DAEOTL010000000
VERSION     DAEOTL010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1190
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.227"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..432
                     /locus_tag="KRH82_003980"
     CDS             <1..432
                     /locus_tag="KRH82_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657221.1"
                     /translation="LPIDVAEFEEKLGVGAESGDYRIIEKVLAFANEVHEHTSVYQLN
                     ELDFMYRQLSSDMQEEYVSLLTVFENLEALYICRNVITVYPDCKSMIDVARQKLMNDP
                     TFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEHGIFELPE"
     gene            450..953
                     /locus_tag="KRH82_003981"
     CDS             450..953
                     /locus_tag="KRH82_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBG8657222.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIEELNSMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIETSR
                     GMCEIPY"
     gene            1063..>1190
                     /locus_tag="KRH82_003982"
     CDS             1063..>1190
                     /locus_tag="KRH82_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657223.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEF"
BASE COUNT          356 a          216 c          281 g          337 t
ORIGIN      
        1 ctgccgatag atgttgccga gtttgaagaa aagttaggtg tcggtgcaga aagtggggat
       61 taccgcatta ttgaaaaggt gttggctttt gctaatgaag ttcacgaaca taccagcgtg
      121 tatcagctca acgaattaga ttttatgtac cgccagcttt caagcgatat gcaggaagaa
      181 tatgtatcac ttcttacggt gtttgagaat ttagaagcac tttatatttg caggaacgtg
      241 attacggttt atcccgactg caaaagcatg atagatgttg caaggcaaaa gctgatgaac
      301 gacccgacgt tcaaacattt atccgaggac tgtcaagaat attactttga ctttgaagcc
      361 tacgcttctc acttgcagga acacgggaaa tttttagtaa cggaacacgg tatctttgaa
      421 ctgccagagt aggaaatgag gtggtgctta tgattgatga tatggcggtt tatattgcta
      481 atcttggcaa atacaacgag ggctatttag tcggtgcgtg gttcacgttc cccattgacg
      541 aggaagatgt gaaagaaaaa atcggcttga atgaacagta tgaggaatac gcaatccatg
      601 ataccgataa ctttcccatt gcgattggcg agtatgtttc cattgaagaa ctgaactcta
      661 tgtatgaaat gatagaggaa cttcccgact atatcgtaga gtgtctggac gaatttatca
      721 gccactacgg gacgctggaa gaagtcgtgg aacacaagga cgatatttat tattatccag
      781 actgtgaaac catgacagac gttgcctact actacataga cgaattgcag gcacttggcg
      841 acattccacc cagcttacag aactacattg actatgaagc ctacgggcga gatttggata
      901 tgggcggttg cttcattgaa acaagccgag gtatgtgcga gataccatat taacgctgga
      961 agatcagcga caagcattgt tgctactgac agcgtatttc tcttttaagg gacagtctga
     1021 aacatggctg tccttttcta ttttgaaagg agctgaaaga acttgaaaaa gattaaatct
     1081 tatacgggta tctggaacgt ggaaaaagtc ttgtatgcaa ttaatgactt taacttgccc
     1141 tttcccgtta cctttacgca gattacatgg tttgtgatta cagaatttat
//
LOCUS       DAEOTL010000223         1133 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.228, whole genome shotgun sequence.
ACCESSION   DAEOTL010000223 DAEOTL010000000
VERSION     DAEOTL010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.228"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            51..1118
                     /locus_tag="KRH82_003983"
     CDS             51..1118
                     /locus_tag="KRH82_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBG8657224.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKVL
                     DGSEKDRVLNKLEKISKDLNK"
BASE COUNT          486 a          111 c          198 g          338 t
ORIGIN      
        1 taaaaaagta tattttattt aaaaatttat taatacaaag gagatttact atgaaaaata
       61 aattagttta catatgtatt atgagtctat tgctatttgt agtaggatgt tctaataatc
      121 caaataagga aagtaccatt aaaaaagact ctaagaataa ccaaagccaa gttaaagaag
      181 aaaaaagaga acctgtgaaa aaagatataa ctataagttt cgctggtgat gtaactatgg
      241 ggaactataa aggttcatca tattatggca gttttgacca tgaatttaaa agacaaggag
      301 aagattacaa ttattttctt aaaaatgtaa aacctgtatt tgaaaaagat gacttaacag
      361 tggttaattt agaaggtcca cttactacag cgtcaaatgc aaaagaaaaa aaatttgcat
      421 ttaaaggaaa gcctggatat gtaaatattt taaaatctgg aagtgtagag gcagtaagta
      481 ttgcaaataa tcattcagaa gattattttg aagaaggaat gaaagataca cagtttatat
      541 tggacgagaa taaaataaat tattttggat tagggaaaga tgctgttgta gatgtcaaag
      601 gaattaaagt gggtctatta gggtataatg gattatcaac tgaatataat gaaaaaaatt
      661 taaaacaaat ggaagatgat attaagtcct taaaaaagaa atcggatgtt gttgtagtgt
      721 actttcattg ggggatagaa ttagattatt atccagataa aaaacaaaaa gattttgctc
      781 attatgctat agacaaggga gcagatttag ttatggggtc tcacccgcat gtgattcaag
      841 gaatagaaaa gtataaaaat aagtatatag cttatagtct agggaatttt tgctttggag
      901 gaaataagaa tccttctgat acagatagtt atatatatca acaaaccttt actttttcag
      961 ataataaatt aacttcaatt aaagagccaa atataatacc aacttcaata acatctagta
     1021 actccagaaa taattatcaa ccaaaagtat tggatggaag tgagaaggat agagttttaa
     1081 ataaacttga aaaaataagc aaagatttaa ataaataaaa tgtaaaaaaa aat
//
LOCUS       DAEOTL010000224         1100 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.229, whole genome shotgun sequence.
ACCESSION   DAEOTL010000224 DAEOTL010000000
VERSION     DAEOTL010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1100
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.229"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            425..892
                     /locus_tag="KRH82_003984"
     CDS             425..892
                     /locus_tag="KRH82_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBG8657225.1"
                     /translation="MKFLNVLVVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRHFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          435 a           74 c          172 g          419 t
ORIGIN      
        1 agaaagaata tgaaaactaa attagaagaa ctaaaaacta tatttttatt aattataata
       61 tttgaataat ctctttaatc atataaaatg catatacttg taatatttaa aggtgatatt
      121 aatattatta gtgtatatta atattccctt gaaattaaaa aaacatagat atttcagtaa
      181 tctaaaatag tctacaaaaa taacagtttt agcaaaatta ataagaatac atatagattt
      241 aaacctaaaa gtatgaacat gtctgttttt tacaagatta aaatttatat tatatgataa
      301 aattaactta actatttcaa taagacttat aatttttttc tttatactag accttattga
      361 aacctttata gtttaattct aattatatat tataaataaa gtatgtgtat attaaggagg
      421 taatatgaag tttttaaatg ttttagtagt agttgaagat attgagaaat caaaaaagtt
      481 ttattatgat gttttggggt taaaggtaat ctgtgatttt ggagaaaatg ttgtactaga
      541 aggtaatata tcattacaag aaaaaaagct ttggttagaa tttattaata agagtgacag
      601 tgaagttaag ttcaatggaa atgatgctga gttatatttt gaggaagata attttgatac
      661 ttttgttgaa agattgagta caatgaaaga tatagattat gttcatctag ctatagagca
      721 taggtggggt caaagagcaa ttagatttta tgatttagat gggcatatta ttgaggttgg
      781 agaaactatg tcatctgtgt gtagacattt tttagatagt ggtctttcaa tagatgaggt
      841 agctaaaaga atggatgtaa ctgtcgaata tattgaatca gttttagaat agatggatta
      901 tattaaagta aaattgaggt gaaggctgta agtaaacttg tgtgaaaaca aatttgctta
      961 cagtttttat ttttctaaaa taaagaatat aatacttgtt tagctttatt tgagttttta
     1021 aaaatattat gatatttctt atatatttat actaaagttt aaatttagaa aaaatatata
     1081 aaagatagtt atatttacta
//
LOCUS       DAEOTL010000225         1040 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.230, whole genome shotgun sequence.
ACCESSION   DAEOTL010000225 DAEOTL010000000
VERSION     DAEOTL010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1040
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.230"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(74..928)
                     /locus_tag="KRH82_003985"
     CDS             complement(74..928)
                     /locus_tag="KRH82_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657226.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
BASE COUNT          381 a          135 c          112 g          412 t
ORIGIN      
        1 ttttacaaaa aatattctaa accttaatct tatgtattag tatttttatt atttaactta
       61 tgtgtttatt ttattattta tcttttttaa ttgatttaat attttctttg attttattta
      121 aaatatctgt atgcttatta gagcttatgt tggggaatgc tttgattata cgtctatgaa
      181 gtaatttgtg gttagacagc aaagtattaa gtttattttt tagctcatca atacgatttt
      241 tagcatagcg ataattttct ttttctttaa gtatttcaaa cctatcttcc aaagtatcca
      301 gtctattttc aactaaagat tcaagtttgt tttctatagt ttcttgtgta ataagtttgt
      361 agtattcttt cttatctttt aattccttaa ttataagatt gatttgtttt aacttaccat
      421 ttaattgtaa aattgtatgg actgtgataa ctaaatctaa aacaaaataa atttctatag
      481 atatagcaaa tataaatagc acatttttgg agatagagtt aataaagtca accacaatag
      541 gatgtactat aagcattaca atcaatgata atacaccaaa cataagtgag ttttccagac
      601 aaactcttcc atgaatatta aatttatgtt tagaataatc ccaccaagtc atattaaata
      661 ttttttctaa aataaagctc gtacaatact ccattatgct agttataatt atactaaaca
      721 aaaataacaa aggaatattg tgtacaaaag gagtcaaggt agcaactatt gctaatgctc
      781 caaatccata tatagggcaa aatggaccat ttaaaaaacc tctatttaca aattgttttt
      841 gtaaaactga acaatatgta gtttcacaac accatcctat aaagctataa attacaaaat
      901 aaagaaattg aatataaaat gtactcataa gcacctcatt tctagttagt ataacactat
      961 atactcgata ttttattttt atgattaatt tactaaattc aatttacata ttgattatac
     1021 caatttatag aaatttatca
//
LOCUS       DAEOTL010000226          973 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.231, whole genome shotgun sequence.
ACCESSION   DAEOTL010000226 DAEOTL010000000
VERSION     DAEOTL010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..973
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.231"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..197)
                     /locus_tag="KRH82_003986"
     CDS             complement(<1..197)
                     /locus_tag="KRH82_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBG8657227.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEA"
     gene            complement(381..962)
                     /locus_tag="KRH82_003987"
     CDS             complement(381..962)
                     /locus_tag="KRH82_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008370407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HBG8657228.1"
                     /translation="MGNVYHTKEEMIDCVNSFYEGMVQRSEEMKQHSNYKTGENYAYL
                     GLPPCFLIFDEYVAFFEMLGTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFS
                     DGIRDNFNFRVGLGRISELGYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPL
                     VPKGHDFLKTIGSLAQARQDGTATCEAKGDGTD"
BASE COUNT          228 a          259 c          187 g          299 t
ORIGIN      
        1 gcttctggat tgaaccttgc cagttcctta tgcagagttt ccagaagttc ctttgacggc
       61 ttcatttttc cgctttctat cttattgaga tattcccttg ttataccaga agccaccgcc
      121 agcctgcctt gtgagatacc gtaagcaatc cgtttctccc gtaattcttt tatccattgt
      181 tcttcattca gaaccatacc cccaatctgt aaagtgtgaa gtttttaggg gcgacttcac
      241 aaccgatttt tgctaggaaa ccatgccaga agccttatgt ttcctatgtt ttttgtctat
      301 tgtctatttg caaacgtacc cctctgttag ataccgaggg gttttacctg ctggcgtggc
      361 ttacgccaca ccagcaacgg ctagtccgtg ccgtcgcctt tcgcttcgca cgtcgccgtc
      421 ccgtcctgcc ttgcttgtgc aagagaaccg atagtcttca aaaaatcatg tcctttcggg
      481 actaagggcg tgtaaaattc gcttatcacg cttgttccta catcacaata gccacgaccc
      541 ttgatacgct tctggaaaaa ctgctttttc acatcagaac cgaacagcat accatatcct
      601 aactcgctga tacgccccaa tcctacacgg aaattgaagt tatctctgat accgtccgag
      661 aaatactttg cgtctggacg ctggcaggca acgataagga aataacctgc ttgtcgcccc
      721 agcataacga ttttctttaa ctggctaagt aggctcacgc tttctttcgt tcccagcatt
      781 tcaaaaaaag ccacatattc atcaaagata agaaagcagg gtggcagtcc cagataggcg
      841 tagttttcgc ctgtcttgta gttcgagtgt tgcttcattt cctcacttcg ttgtaccatg
      901 ccctcataaa aggaattgac gcaatctatc atttcttctt tggtgtggta cacgtttccc
      961 atgactgttc cca
//
LOCUS       DAEOTL010000227          968 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.232, whole genome shotgun sequence.
ACCESSION   DAEOTL010000227 DAEOTL010000000
VERSION     DAEOTL010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.232"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(2..766)
                     /locus_tag="KRH82_003988"
     CDS             complement(2..766)
                     /locus_tag="KRH82_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBG8657229.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
BASE COUNT          348 a          140 c           94 g          386 t
ORIGIN      
        1 cttataaaac atttacatta aattctgata aaatatctac tatatcagga gtaggcgttt
       61 tttctgtaat tatagaacta atatcttcta aatgagcaaa cttgaaattt ccatcaaatt
      121 taaacttttt atcttccata actataaata cttttttact tgaatttatt atagccttct
      181 tcgtaagacc atcttcaatt tcaaaagttg taagtgaaga gttgaataca tctactccac
      241 aacttcccat aaaagtctta tcaaacttat atttcgatat aaactctata gttggagtac
      301 cgacaaaacc gtctaaactg agatttaata aacctccagt ggaaattata tttaaattat
      361 ttggttttga agtaactaca tttagtatat ccagcatatt tgtaacaagt gttacttttt
      421 tattactttc agctaacaac ttcgcaagca agatgttaat tgtagagata tctaaaaata
      481 tagtttctct atcttcaatt aaattaaatg ctttttctgc tattattttc tttgttggaa
      541 tattaatttc ttttctgtct tttgtatcct gattttctag tgtttctcta gctagtacag
      601 ctcctccata aattcttctt attgaagaaa tcttttctat attttttaaa tcttttctta
      661 tacaatcttc tgtaacatta aatttagaac tgagctcttt gacagtaact ctaccttctt
      721 tttttaggat atttaatata gcttggattc tttcttctgc aaacattttc tacctctttt
      781 cgcaatatag tattatagta aatattataa gataaaatac aatatatcaa ctattttaac
      841 atgaaataca aaattaattt aatataaaaa gtatgttttt tctaactata tatttagaat
      901 ttagtaaata aaaaaattat aaaactaaga aggaaaagta aaacaataat aaaaaataaa
      961 aaacaata
//
LOCUS       DAEOTL010000228          924 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.233, whole genome shotgun sequence.
ACCESSION   DAEOTL010000228 DAEOTL010000000
VERSION     DAEOTL010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.233"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>924
                     /locus_tag="KRH82_003989"
     CDS             <1..>924
                     /locus_tag="KRH82_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBG8657230.1"
                     /translation="AYYELIPYNYSFLSAEQKFIVHDSFRQLIAQSREGKIHALQIAT
                     ESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMIGDNQVDYRFFLGFKLMVTEE
                     QLNLKNIKKSAWLTFTEFLHEVNHTLMNDFVSMPNDEINRYMKMEKLLENKISRRFKV
                     RRLETNDFGYLIEHLYGRDGVAYEDYEYQLPKKKLRRETQIKYYDLIRPTRCVIEESQ
                     RYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQQQFTFPVDTSMNVEIVENRK
                     ALTTVRNKKKELKDLDNHAYQAGSETSSNVVD"
BASE COUNT          306 a          181 c          210 g          227 t
ORIGIN      
        1 gcctattatg agctgatacc gtacaactat tctttcttat ccgcagagca gaaatttatc
       61 gtgcatgaca gctttcgaca gctcattgca cagtcccgtg agggtaaaat tcatgcgttg
      121 cagattgcca cagaaagctc aatccgaagt atgcaggagc agtcaaaaaa gctggtaact
      181 ggaaaattaa aggaagttgc ctatcagaag atagacgaac agaccgaagc gttagtatct
      241 atgattgggg ataatcaagt ggactaccgc ttttttcttg gctttaagct catggttacg
      301 gaagaacagc tcaatctgaa gaacatcaaa aaatcggcgt ggctgacgtt cacggaattt
      361 ctccatgaag tgaaccacac gctgatgaat gactttgttt ccatgccaaa tgatgaaatc
      421 aaccgctaca tgaaaatgga aaagttactg gaaaacaaaa tatcccgtcg tttcaaggtg
      481 cgacgcttgg aaacaaacga cttcgggtat ctcatagaac atctttacgg tagggacggt
      541 gtcgcttatg aagattatga gtatcagtta ccaaagaaga aattgaggag agaaacgcag
      601 ataaaatact acgaccttat tcgtccgaca agatgtgtga ttgaggaaag ccaaaggtat
      661 ttacgattgg aacatgagga caaggaaagc tatgtgtcct actttaccgt caatgcgatt
      721 gtgggcgagc tggattttcc gtccagtgaa atcttctatt tccagcaaca gcaattcaca
      781 ttccccgttg atacttctat gaatgtagaa atcgtggaaa atcggaaagc attaacgaca
      841 gtccgcaaca agaaaaagga attgaaagac cttgacaatc acgcttatca agcaggaagt
      901 gaaaccagct caaatgtggt ggac
//
LOCUS       DAEOTL010000229          924 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.234, whole genome shotgun sequence.
ACCESSION   DAEOTL010000229 DAEOTL010000000
VERSION     DAEOTL010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.234"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            80..>924
                     /locus_tag="KRH82_003990"
     CDS             80..>924
                     /locus_tag="KRH82_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBG8657231.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPE"
BASE COUNT          369 a          108 c          192 g          255 t
ORIGIN      
        1 tgaaatgcta ataaattaaa aaagtgaaat atcaaaataa aacgtcaaca aactaaaaat
       61 tatatggggg aatatcaaaa tgttaaatga aacaagaaaa aaacaattaa ctgaagtatg
      121 ccaagactta ataagaaatg ctagttattc aggtcaagaa gaaaacgtag taaaagctat
      181 agaagaaaat tttgctttac taggttttga tagttggtca agagatagat atggaaatat
      241 agtaggatgt ataaaaggaa ataaaccagg taaaaaaata ttatttgacg ggcatataga
      301 tacagttcca gttccagatg caagtaaatg gagtgttcct ccttttgaag cgagaatagt
      361 agatgggaaa atatatggta gaggaacttc tgatatgaag gggcaagtaa gtgctatgat
      421 ggctgctgtt tcatattttg cagaagatac taacaaagac tttgaaggtg aattgtatgt
      481 agcaggtgtt gttcatgaag aaatatttga aggtgtttca gctagagaga taagtaaggc
      541 tgttcaacct gattatgttg taataggtga atcttcagaa ttaaacctaa agataggtca
      601 aagaggtaga ggagaaatag tagtagaaac ttttggtaaa ccagctcact ctgctaatcc
      661 agaaaaaggt ataaatgcag tttataaaat ggctaatgta atccaaaaga tacaacaatt
      721 agtacctcca actcatccag ttttaggtga tggaatatta gttttaacag atataaaatc
      781 ttctccatat ccaggagcat cagtagtgcc agattattgc aaagctactt ttgatagaag
      841 attattagtt ggagaaacaa gagaaggcgt attagctcca atacaagctt tattagatga
      901 aatgatgaaa gaagacccag aatt
//
LOCUS       DAEOTL010000230          807 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.235, whole genome shotgun sequence.
ACCESSION   DAEOTL010000230 DAEOTL010000000
VERSION     DAEOTL010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.235"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>807
                     /locus_tag="KRH82_003991"
     CDS             <1..>807
                     /locus_tag="KRH82_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBG8657232.1"
                     /translation="ISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGASIVAF
                     SLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLRIMGK
                     SNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQMIKSL
                     GINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKK
                     FTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGN"
BASE COUNT          240 a          120 c          131 g          316 t
ORIGIN      
        1 ttatatctgt aatgacgcaa agtttaattt tatcgattat ggcactgggg gtttatataa
       61 cttacaaaat cttagatttt ccagatatgt ctgctgatgg tagctacaca atgggtgctt
      121 ctattgtagc attttctctt actaatggta tttctcctgt agtagcaact ttaatggcta
      181 tcttatgtgg ttgtactgct ggtcttgtta cagggattct tcacattaag tttaagatat
      241 ctaatttact ttctggtatt ttagttatgg gaatgctata ctctatcaat ttaagaataa
      301 tgggaaaatc aaatattcct ctatttagct ttaaacactt attcaatggg gaaatatctc
      361 ctatagtttt agccttagct tttgtattca tctgtaaagt ccttttagat ttattcctaa
      421 aaacaggtct tggatacact ttaaaaggtg ttggtgataa ctctcaaatg attaaatccc
      481 taggtataaa tataggttct ataaaaatac taggacttat gatttcaaat ggacttatag
      541 ctttatctgg tagtcttatg gctcagttct tgggattctc agatgtaaat atgggtatag
      601 gaactttagt tcttggaatt gcctctatca taattggtat tacactattt aagaaattta
      661 cttttatcaa agatactact gcaataattg ttggctcttt tatataccaa ttcactatat
      721 actttgcaat gagtttagga atgttatcaa ctgacttaaa actaataact gccatagtta
      781 taatagcttt cctagctact ggtaact
//
LOCUS       DAEOTL010000231          795 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.236, whole genome shotgun sequence.
ACCESSION   DAEOTL010000231 DAEOTL010000000
VERSION     DAEOTL010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.236"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..703
                     /locus_tag="KRH82_003992"
     CDS             <1..703
                     /locus_tag="KRH82_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBG8657233.1"
                     /translation="VMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGE
                     LIKHREDDREYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLNEADIINRFEIRLR
                     NERAYYAVRDLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQ
                     SLKLTTKPEPYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQATLSEKHEM
                     IIKQQTTPAKDLVES"
     gene            716..>795
                     /locus_tag="KRH82_003993"
     CDS             716..>795
                     /locus_tag="KRH82_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBG8657234.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILS"
BASE COUNT          257 a          141 c          202 g          195 t
ORIGIN      
        1 cgtgatgaag cgtatcgacc ttgctatcaa cgaccatacg ggcattttgg atattccaga
       61 gcttgcggaa aaatgcagga aacgggaata tatcggaaag tccagaagtt ataagtttta
      121 ccagtcgggc gagcttatca agcacagaga ggacgacaga gaatatatgg gacgcactct
      181 ttatcttggt tcgctgaaat cagatgtata tttctgtatc tatgaaaagg actatgagca
      241 gtacgtcaag ttgggtacac cgcttaatga agccgacatt atcaaccgtt ttgagatacg
      301 gcttagaaat gagcgtgcct attatgcagt acgagatttg ctgacctatt atgacgcaga
      361 acagaccgcc ttttctatca tcaaccagta tgtgcggttt gttgatgaag aaccagacaa
      421 gcgaaaaaat gactggaaac tcaatgaccg ctgggcttgg tttatcggcg ataacagaca
      481 gagcttgaag ctgacgacaa agccagagcc ttacacctta gaccgtacat tgcggtgggt
      541 acaaaggcag gtagcaccta ccttgaaaat gctgaaaaag attgataagg gaaacgggac
      601 tgactatatg gaaacgattg aaaagcaggc aactttgagt gaaaagcatg aaatgataat
      661 caaacagcag acgacccctg caaaagattt ggtggaaagt taggagtgat aaaaaatgtg
      721 ggaattagta aaagacttcc tgctggtatc tatgggaatg ggtatcggcg tagtcttgat
      781 gtgtattttg agtat
//
LOCUS       DAEOTL010000232          740 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.237, whole genome shotgun sequence.
ACCESSION   DAEOTL010000232 DAEOTL010000000
VERSION     DAEOTL010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.237"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..162
                     /locus_tag="KRH82_003994"
     CDS             <1..162
                     /locus_tag="KRH82_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF961 family protein"
                     /protein_id="HBG8657235.1"
                     /translation="VEIPVQAGEKKFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVA
                     DDIVAVEEK"
     gene            178..561
                     /locus_tag="KRH82_003995"
     CDS             178..561
                     /locus_tag="KRH82_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBG8657236.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGSPQNHTPQGQSKK"
BASE COUNT          263 a          112 c          184 g          181 t
ORIGIN      
        1 gtggaaattc ccgtgcaggc tggcgaaaag aagttcaagt atgagcagaa agtaaaactt
       61 gtcaatccga agttatacgg cagaggttac gcaatcgggg atatgggaca taccgattat
      121 gtattagttg ctgatgatat tgtagcagtt gaagaaaagt aaaggagtga agaatttatg
      181 agattatcaa acgggtttgt tattgacaaa gaaaaaacat ttggagaatt aaaatttaca
      241 gcggtgcgtg atgtgttctt acagaatgag gacgggacac cgagtaccca gcttaaaaag
      301 cgtatctatg atttgaagtg cagtctgcat ggtggaatta tccccgtgtc tgtaccgcca
      361 gaagtaccgt taagggaatt tccgtacaat gcagtcgtgg agcttgtcaa tccagtagcc
      421 gatacagtat cacgaaaaac ttatacgggt gcagatgtgg actggtatgt aaaggcagag
      481 gatattgtgt tgaagaataa aggcaaccag aacgcaggca gtccacagaa ccatacaccg
      541 caaggacagt caaaaaaata aatctaggtc atagatttta ctctgaaatt acagtataat
      601 gagccaaaag agccgtattt aagctatgta aaacaatttt gacaaggaaa aaaggctttg
      661 tcgaagatat tggatagaca tttgagggtt aatatatgac aatgacaccg aaaggagcaa
      721 tcgaaatatg gaaataggta
//
LOCUS       DAEOTL010000233          715 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.238, whole genome shotgun sequence.
ACCESSION   DAEOTL010000233 DAEOTL010000000
VERSION     DAEOTL010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..715
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.238"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..663
                     /locus_tag="KRH82_003996"
     CDS             <1..663
                     /locus_tag="KRH82_003996"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBG8657237.1"
                     /translation="ADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEAIEQLKEYGVD
                     RPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAEAGDGKPRFVG
                     GDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNPLRGDEKVISG
                     ESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKYRDIVWNGECQ
                     SK"
BASE COUNT          276 a           91 c          168 g          180 t
ORIGIN      
        1 gctgatgacc atggagtaat ggttcaagat acagcatggg acggatatga agaaatacca
       61 gcatggataa tgcaaggata tggaactatg gctaaagaag ctatagaaca attaaaagaa
      121 tatggagtag atagaccaac acacgtattt gttcaagcag gagttggttc acttgctggt
      181 gcagttcaag gatatgttgc ttcaatatat gatgaatgcc caataacagt agtagtagag
      241 gctgatgagg ctgattgtta ctataaatca gcagaagctg gagatggaaa accaagattt
      301 gttggaggag atatgccaac tataatggca gggcttgctt gtggagaacc aaacactata
      361 ggttttgaag tgttaaaaaa ttattcatca gcattcgttt cagcaccaga ctgggtatct
      421 gctaaaggta tgagaatatt aggaaaccct ctaagaggag atgagaaagt aatctctgga
      481 gaatctggag cagttacaac tggagcatta gtttcaatcc ttgaaagtga agatttaaaa
      541 gacttaagag aagctttgaa actagatgag aactctaaag tattattaat aagtacagaa
      601 ggagatactg accctgataa atatagagat atagtttgga atggtgaatg ccaaagtaaa
      661 taaaagactt aaggaaaaga aaaacttaac aaataaatga aaaatttaag gaaaa
//
LOCUS       DAEOTL010000234          696 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.239, whole genome shotgun sequence.
ACCESSION   DAEOTL010000234 DAEOTL010000000
VERSION     DAEOTL010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.239"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            108..578
                     /locus_tag="KRH82_003997"
     CDS             108..578
                     /locus_tag="KRH82_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBG8657238.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTVIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
BASE COUNT          308 a           55 c          124 g          209 t
ORIGIN      
        1 taaaaaagta aaaataaagg attaataaaa ggtactgaag agatagagaa aaaaatgtta
       61 atagaagata ctgaaaaaat agaaataaaa aattaggagg aaaatttatg aaatatcagg
      121 tttcattatt agcagtgaag gatattgaag tatcaaaaaa attttacaaa gaattatttg
      181 agcaagaaat tgaattggac ttaggtaaaa atgtaacatt taaaggagga tttgctatac
      241 aagaagactt cgcatggctt acagggatta atccagatac agttatacaa aaatcaaata
      301 atatggaact ttattttgag gttgatgatt ttgacgaatt tattgaaaaa ctcaattatt
      361 ataaagatgt agagtttgtc cataagccac taaaacatga atggcaacaa agagtagtgc
      421 gtatttatga cccagataag catattattg agataggaga gtctatggaa gttatagcta
      481 gaagatattt atctgaggga tattctgtag aagaaacttc taaaataatt caacatccaa
      541 ttgaatttgt aaagcagtgt gaaaatagta aggaatgatt gtttaaatta taattattta
      601 gtagaaatta attgtggtag aactaattca agataatata taggactagt atttgacaaa
      661 tgtcataaat taaattaaaa taaagaaaat attaat
//
LOCUS       DAEOTL010000235          577 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.240, whole genome shotgun sequence.
ACCESSION   DAEOTL010000235 DAEOTL010000000
VERSION     DAEOTL010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.240"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>577
                     /locus_tag="KRH82_003998"
     rRNA            <1..>577
                     /locus_tag="KRH82_003998"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEOTL010000236          547 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.241, whole genome shotgun sequence.
ACCESSION   DAEOTL010000236 DAEOTL010000000
VERSION     DAEOTL010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..547
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.241"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>547
                     /locus_tag="KRH82_003999"
     CDS             <1..>547
                     /locus_tag="KRH82_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBG8657239.1"
                     /translation="KREYIGKSRSYKFYQSGELIKHSEDDREYMGRTLYLGSLKSDVY
                     FCIYEKDYEQYVKLGTPLEEADIINRFEIRLRNERAYYAVRDLLTYYDAEQTAFSIIN
                     QYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPEPYTLDRTLRWVQRQVAP
                     TLKMLKKIDKGNGTDYMETIEQ"
BASE COUNT          177 a          102 c          135 g          133 t
ORIGIN      
        1 aaacgggaat atatcggaaa gtccagaagt tataagtttt accagtcggg cgagcttatc
       61 aagcacagcg aggacgacag agaatatatg ggacgtaccc tttatcttgg ttcgctgaaa
      121 tctgatgtat atttctgtat ctatgaaaag gactatgagc agtatgtcaa gttagggaca
      181 cctctggaag aagccgatat tatcaaccgt tttgagatac ggcttagaaa tgaacgtgcc
      241 tattatgcag tacgggattt gctgacgtat tacgacgcag agcagaccgc cttttctatc
      301 atcaatcagt atgtacggtt tgttgatgaa gaaccagaca agcggaaaaa tgactggaaa
      361 ctcaatgacc gctgggcttg gtttatcggc gataatcggc aaagtctgaa actgacgaca
      421 aagccagaac cttatacctt agatcgtaca ttgcgttggg tacaaaggca ggtagcaccg
      481 accttgaaaa tgctgaaaaa gattgataag ggaaacggta cagattacat ggagacaatc
      541 gaacagc
//
LOCUS       DAEOTL010000237          497 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.242, whole genome shotgun sequence.
ACCESSION   DAEOTL010000237 DAEOTL010000000
VERSION     DAEOTL010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.242"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..>497)
                     /locus_tag="KRH82_004000"
     rRNA            complement(<1..>497)
                     /locus_tag="KRH82_004000"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          118 a          148 c          110 g          121 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatg
//
LOCUS       DAEOTL010000238          490 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.243, whole genome shotgun sequence.
ACCESSION   DAEOTL010000238 DAEOTL010000000
VERSION     DAEOTL010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.243"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>490
                     /locus_tag="KRH82_004001"
     CDS             <1..>490
                     /locus_tag="KRH82_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBG8657240.1"
                     /translation="FLALATVVTALPTTPVHAESKQYWTESKERVGIVEKVMNDGSIG
                     STFNEGHLTVEGEDAYCIDINTDFRNGYKTRADASTRMSADQISDVALSIEYVKQYTD
                     SHSGISKNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDEVFSGARAFVKE
                     NKG"
BASE COUNT          148 a          103 c          120 g          119 t
ORIGIN      
        1 gcttcttagc tcttgcaact gtcgttactg ctttaccgac gacacccgtt catgcagaaa
       61 gcaagcaata ctggacggag tcaaaagagc gtgtcggtat cgttgaaaaa gtaatgaatg
      121 acggttcgat tggttctacc tttaatgagg gacatttaac cgttgagggc gaggacgctt
      181 actgtatcga cattaacaca gattttagga acggctacaa gaccagagct gacgcaagca
      241 cccgtatgag tgccgaccag ataagcgacg ttgccttatc tatcgaatat gtgaaacagt
      301 acacagacag ccacagcgga ataagcaaaa atcacgctta ccttttaaga cagcttgtag
      361 tctggcagag attgagcgta catcttggct ggcaatgtga taacgtgcga gcttcttatg
      421 atgaaattcc aaaggcaacg caggacgaag ttttctctgg tgctagagcc tttgtcaaag
      481 aaaataaagg
//
LOCUS       DAEOTL010000239          473 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.244, whole genome shotgun sequence.
ACCESSION   DAEOTL010000239 DAEOTL010000000
VERSION     DAEOTL010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.244"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>473
                     /locus_tag="KRH82_004002"
     CDS             <1..>473
                     /locus_tag="KRH82_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021394011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HBG8657241.1"
                     /translation="FAPANTDANNIEGQAILYQNEFLTLNGKKYYFGSDSKAVTGWRI
                     INNKKYYFNPNNAIAAIHLCTINNDKYYFSYDGILQNGYITIERNNFYFDANNESKMV
                     TGVFKGPNGFEYFAPANTHNNNIEGQAIVYQNKFLTLNGKKYYFDNDSKAVTGWQT"
BASE COUNT          182 a           64 c           73 g          154 t
ORIGIN      
        1 tttgcacctg ctaatacgga tgctaacaac atagaaggtc aagctatact ttaccaaaat
       61 gaattcttaa ctttgaatgg taaaaaatat tactttggta gtgactcaaa agcagttact
      121 ggatggagaa ttattaacaa taagaaatat tactttaatc ctaataatgc tattgctgca
      181 attcatctat gcactataaa taatgacaag tattacttta gttatgatgg aattcttcaa
      241 aatggatata ttactattga aagaaataat ttctattttg atgctaataa tgaatctaaa
      301 atggtaacag gagtatttaa aggacctaat ggatttgagt attttgcacc tgctaatact
      361 cacaataata acatagaagg tcaggctata gtttaccaga acaaattctt aactttgaat
      421 ggcaaaaaat attattttga taatgactca aaagcagtta ctggatggca aac
//
LOCUS       DAEOTL010000240          458 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.245, whole genome shotgun sequence.
ACCESSION   DAEOTL010000240 DAEOTL010000000
VERSION     DAEOTL010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..458
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.245"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..299)
                     /locus_tag="KRH82_004003"
     CDS             complement(<1..299)
                     /locus_tag="KRH82_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657242.1"
                     /translation="MRKIWNRGHRIRASDKHLVYHFSIGTLLFLFVAVLLLLNIKQLM
                     RTDWEHFSLLENGLTLSPYNFITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLA"
BASE COUNT          152 a           96 c           94 g          116 t
ORIGIN      
        1 gccagctttt gacggtgcag gagcttcttg aaactgtcgt aacagaagcg gtaatacaga
       61 aaagcgacca atgcacaaac accagtcgct atcagtatgg ttatgaagtt gtaaggggaa
      121 agcgtcaagc cgttctctaa caagctgaaa tgctcccagt cggtacgcat gagctgtttg
      181 atattcagta gcaggagaac cgccacgaat aaaaacagaa gcgtccctat ggaaaaatgg
      241 tagacaaggt gcttgtcgct ggctctgata cggtgtcctc tattccaaat cttacgcata
      301 aatcattcac tcctttctgg gtacgaaaaa agcagtcaat catatagact aactgctttg
      361 taaatgttgc aagatataat cataaatctg catttttagt tatattaagg tcgcacatat
      421 aatgccaatt acaccaatag ccaaaaataa cagtccaa
//
LOCUS       DAEOTL010000241          397 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.246, whole genome shotgun sequence.
ACCESSION   DAEOTL010000241 DAEOTL010000000
VERSION     DAEOTL010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.246"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..238)
                     /locus_tag="KRH82_004004"
     CDS             complement(<1..238)
                     /locus_tag="KRH82_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBG8657243.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     CTDWEHFSLLENDLTLSPYNFITILIATGACVLVA"
BASE COUNT          133 a           82 c           77 g          105 t
ORIGIN      
        1 aagcgaccaa tacacaagca ccagtcgcta tcagtatggt tatgaagttg taaggggaga
       61 gcgtcaagtc gttttctaac aagctgaaat gctcccaatc ggtacacatg agctgtttga
      121 tattcagtag cagaagaacc gccacgaaca caaacagaag cgtccctatg gaaaagtggt
      181 agacaaggtg cttgtcgctg gctctgatac gatgtccttt attccaaatc ttacgcataa
      241 atcattcgct cctttctggg tatgaaaaaa gcagtcaatc gtatagacta actgctttgt
      301 aaatgttgca agatataatc ataaatctgc atttttagtt atattaaggt cgcacatata
      361 atgccaatta caccaatagc caaaaataac agtccaa
//
LOCUS       DAEOTL010000242          360 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.247, whole genome shotgun sequence.
ACCESSION   DAEOTL010000242 DAEOTL010000000
VERSION     DAEOTL010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.247"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>360
                     /locus_tag="KRH82_004005"
     CDS             <1..>360
                     /locus_tag="KRH82_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBG8657244.1"
                     /translation="KKYVAPAIGQLTFDATDKQIKMASGDKTVDPSDNTYILKLTNGT
                     VKDGDVKANVKVAGLPSGLDYTAVGNRSANTITITVSGTASQSIQNDLNNVSVLVKAG
                     AVSGTGATDSIANTTFEI"
BASE COUNT          161 a           51 c           67 g           81 t
ORIGIN      
        1 aaaaaatatg tggcgccagc aataggtcaa ttaacttttg atgcaacaga taaacaaata
       61 aaaatggcat caggagataa gacagtagat ccatcagata acacatatat actaaaatta
      121 acaaatggga cagtaaaaga tggagatgta aaagctaatg ttaaagtagc aggattacca
      181 tcaggactag attatacagc agtaggaaat agatcagcaa atacaataac aattacagta
      241 tcaggaacag caagccaatc aatacaaaat gatttaaata atgtaagtgt gctagttaaa
      301 gcaggagcag tatctggaac aggagctaca gattcaattg caaatacaac atttgaaatt
//
LOCUS       DAEOTL010000243          357 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.248, whole genome shotgun sequence.
ACCESSION   DAEOTL010000243 DAEOTL010000000
VERSION     DAEOTL010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.248"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          137 a           51 c           39 g          130 t
ORIGIN      
        1 cctttgaaaa tattttaaat ggttttttaa atttggtttt aaaaaatgat tttgatataa
       61 aaaaaccaca cagtatatat aactgtatgg caaaaattcg aataagccac acagtataat
      121 ccatgtggct ctatattatg atgataaaat aaaaacttta acaacaatta ctatagccaa
      181 catagataca atccttaaaa atcataatcc taaggggctt gtatctatgt tatgacaatt
      241 tgtcttaact taggtacaaa ccctaactaa attggctact aaaaaatcgt acttgtttgt
      301 ttaataaagt cttcatattt acctctcctt ttaatttaat aattttgaaa attttgt
//
LOCUS       DAEOTL010000244          341 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.249, whole genome shotgun sequence.
ACCESSION   DAEOTL010000244 DAEOTL010000000
VERSION     DAEOTL010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.249"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>341
                     /locus_tag="KRH82_004006"
     CDS             <1..>341
                     /locus_tag="KRH82_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021414120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657245.1"
                     /translation="KKYYFDNDSKAVTGWRIINNEKYYFNPNNAIAAVGLQVIDNNKY
                     YFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKHFYFDSDCVVKIGVFSTS
                     NGFEYFAPANT"
BASE COUNT          115 a           45 c           59 g          122 t
ORIGIN      
        1 aaaaaatatt attttgataa tgactcaaaa gcagtcactg gatggagaat tattaacaat
       61 gagaaatatt actttaatcc taataatgct attgctgcag tcggattgca agtaattgac
      121 aataataagt attatttcaa tcctgacact gctatcatct caaaaggttg gcagactgtt
      181 aatggtagta gatactactt tgatactgat accgctattg cctttaatgg ttataaaact
      241 attgatggta aacactttta ttttgatagt gattgtgtag tgaaaatagg tgtgtttagt
      301 acctctaatg gatttgaata ttttgcacct gctaatactt a
//
LOCUS       DAEOTL010000245          323 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.250, whole genome shotgun sequence.
ACCESSION   DAEOTL010000245 DAEOTL010000000
VERSION     DAEOTL010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..323
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.250"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..>323)
                     /locus_tag="KRH82_004007"
     rRNA            complement(<1..>323)
                     /locus_tag="KRH82_004007"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           65 a           89 c           64 g          105 t
ORIGIN      
        1 ctacttaacg taactcgttg gcccgttcta caaaaagtac gcggtcacac aagaaatgtg
       61 cttccacagc ttgtaagtgc agggtttcag gttctatttc actcccctcc cggggttctt
      121 ttcacctttc cctcacggta ctatacgcta tcggtcacta ggtagtattt agccttggag
      181 ggtggtccct cctgcttccc acagggtttc acgtgtcccg tggtactctg gatcatatct
      241 aaagtcttct cgtttaacat acaggactat taccttctgt ggtgggtctt tccaaacctc
      301 ttcaattacg atacctcttc gtt
//
LOCUS       DAEOTL010000246          315 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.251, whole genome shotgun sequence.
ACCESSION   DAEOTL010000246 DAEOTL010000000
VERSION     DAEOTL010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..315
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.251"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(<1..268)
                     /locus_tag="KRH82_004008"
     rRNA            complement(<1..268)
                     /locus_tag="KRH82_004008"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           77 a           82 c           53 g          103 t
ORIGIN      
        1 ggctaatccg cgttcgctcg ccgctactta cggaatcgaa tttctttctc ttccttcagg
       61 tacttagatg tttcagttcc ctgagttccc ctcattaagc tatgtattca cttaatgata
      121 cttagacatt actctaagtg agtttcctca ttcggaaatc ttcggatcaa agtttacgtg
      181 caactccccg aagcttatcg cagcttatca cgtccttcat cggctcctag tgccaaggca
      241 tccgccctgc acccttaata acttgaccag ttaaaaaggt ttgatagatt agaagctatc
      301 aacttcgata atttt
//
LOCUS       DAEOTL010000247          296 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.252, whole genome shotgun sequence.
ACCESSION   DAEOTL010000247 DAEOTL010000000
VERSION     DAEOTL010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.252"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            167..283
                     /gene="rrf"
                     /locus_tag="KRH82_004009"
     rRNA            167..283
                     /gene="rrf"
                     /locus_tag="KRH82_004009"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          104 a           42 c           56 g           94 t
ORIGIN      
        1 ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta ctaacttcaa
       61 ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact attgacattt
      121 aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg gttataatag
      181 caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta gcgctgatgg
      241 tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt ccaagg
//
LOCUS       DAEOTL010000248          273 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.253, whole genome shotgun sequence.
ACCESSION   DAEOTL010000248 DAEOTL010000000
VERSION     DAEOTL010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..273
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.253"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
BASE COUNT          113 a           19 c           27 g          114 t
ORIGIN      
        1 aaagtaactt ataaaattat atataaataa taaaattaat tttactatat acccatatat
       61 ttagttatat tgcaggcaga atgtggttta ccataaccaa aaggataata aaaaatattt
      121 ttctatattt ttattatctt tttgtaaaag atttattatt tattgaatta aattaatagg
      181 cagtagaggc atagttgata aaattaatga agaaattaaa cttatgaata taaatttatt
      241 attgagtttt aatattacat ttattattct ctt
//
LOCUS       DAEOTL010000249          271 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.254, whole genome shotgun sequence.
ACCESSION   DAEOTL010000249 DAEOTL010000000
VERSION     DAEOTL010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..271
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.254"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            24..>271
                     /locus_tag="KRH82_004010"
     CDS             24..>271
                     /locus_tag="KRH82_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBG8657246.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIV"
BASE COUNT          108 a           31 c           43 g           89 t
ORIGIN      
        1 atcagaaaaa agaggtgttg tagatgttac aaattaaaaa tctttcaaag agtttcccta
       61 atccatatgg tgaacctaat actatctttg aaaatttatc aatcgatata gaagatggtg
      121 aatttgtaag tatcataggt agtaatggaa ctggtaaatc tactttatta aatataatat
      181 ctgggcttat aaaagaatct tctggtcaaa ttactttaga tagtactact ataacaaatt
      241 tagctgagta taaaagaact caaatagtaa g
//
LOCUS       DAEOTL010000250          257 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.255, whole genome shotgun sequence.
ACCESSION   DAEOTL010000250 DAEOTL010000000
VERSION     DAEOTL010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.255"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>257
                     /gene="tuf"
                     /locus_tag="KRH82_004011"
     CDS             <1..>257
                     /gene="tuf"
                     /locus_tag="KRH82_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011793521.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBG8657247.1"
                     /translation="MITGAAQMDGAILVCSATDGPMPQTREHILLSRQVGVPYIVVFL
                     NKCDMVDDEELLELVEMEVRDLLTEYDFPGDDTPIVRGSAL"
BASE COUNT          101 a           34 c           57 g           65 t
ORIGIN      
        1 atgataacag gagcagcaca aatggacgga gcaatattag tttgttcagc aacagatgga
       61 ccaatgccac aaacaagaga gcatatacta ttatcaagac aagttggagt accatatata
      121 gtagtattct taaacaaatg tgacatggta gatgatgaag agttattaga gttagtagag
      181 atggaagtaa gagatttatt aacagaatat gatttcccag gagatgacac tccaatagta
      241 agaggttcag cattaat
//
LOCUS       DAEOTL010000251          254 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.256, whole genome shotgun sequence.
ACCESSION   DAEOTL010000251 DAEOTL010000000
VERSION     DAEOTL010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.256"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>254
                     /locus_tag="KRH82_004012"
     CDS             <1..>254
                     /locus_tag="KRH82_004012"
                     /inference="COORDINATES: protein motif:HMM:NF013550.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HBG8657248.1"
                     /translation="DGATGVTGPTGATGATGANGLVGPTGATGAAGTPGATGPTGATG
                     PTGVGITGATGATGATGPTGADGATGPTGATGNTGADGVAG"
BASE COUNT           98 a           55 c           85 g           16 t
ORIGIN      
        1 gacggagcaa caggagtaac aggtccaaca ggagcaacag gggcaacagg agcaaatgga
       61 ttagtaggcc caacaggagc aacaggagca gcaggaacac ctggagcaac aggtccaaca
      121 ggagcaacag gcccaacagg agtaggaata acaggagcaa caggggcaac aggagcgaca
      181 ggtccaacag gagcagatgg agcaacaggt ccaacaggag caacaggaaa tacaggagca
      241 gatggagtag cagg
//
LOCUS       DAEOTL010000252          245 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.denovo.257, whole genome shotgun sequence.
ACCESSION   DAEOTL010000252 DAEOTL010000000
VERSION     DAEOTL010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..245
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.denovo.257"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..>245
                     /locus_tag="KRH82_004013"
     CDS             <1..>245
                     /locus_tag="KRH82_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657249.1"
                     /translation="YYELIPYNYSFLSAEQKFIVHDSFRQLIAQSREGKIHALQIATE
                     SSIHSMQEQSKKLVTGKLKEVACQKIDEQTEALVSMIG"
BASE COUNT           78 a           49 c           57 g           61 t
ORIGIN      
        1 tactatgagc tgataccgta caactattct tttctatccg cagagcagaa atttatcgtg
       61 catgacagtt tccgacagct tatcgcacag tcccgtgagg gtaaaattca tgcgttgcag
      121 attgctacgg aaagctcaat ccatagtatg caggagcagt caaagaagct ggtaactgga
      181 aaattaaagg aagttgcctg ccagaaaata gacgaacaga ccgaagcgtt agtatctatg
      241 attgg
//
LOCUS       DAEOTL010000253        16272 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.guided.091, whole genome shotgun sequence.
ACCESSION   DAEOTL010000253 DAEOTL010000000
VERSION     DAEOTL010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16272
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.guided.091"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            246..863
                     /locus_tag="KRH82_004014"
     CDS             246..863
                     /locus_tag="KRH82_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBG8657250.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="KRH82_004015"
     CDS             971..3502
                     /locus_tag="KRH82_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBG8657251.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="KRH82_004016"
     CDS             3936..4637
                     /locus_tag="KRH82_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBG8657252.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="KRH82_004017"
     CDS             4687..5769
                     /locus_tag="KRH82_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBG8657253.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="KRH82_004018"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="KRH82_004018"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBG8657254.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNNDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="KRH82_004019"
     CDS             7127..7933
                     /locus_tag="KRH82_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBG8657255.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="KRH82_004020"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="KRH82_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBG8657256.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGVKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="KRH82_004021"
     CDS             10403..11023
                     /locus_tag="KRH82_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBG8657257.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="KRH82_004022"
     CDS             complement(11189..11725)
                     /locus_tag="KRH82_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBG8657258.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="KRH82_004023"
     CDS             complement(11838..12512)
                     /locus_tag="KRH82_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBG8657259.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..14589
                     /gene="asnB"
                     /locus_tag="KRH82_004024"
     CDS             12715..14589
                     /gene="asnB"
                     /locus_tag="KRH82_004024"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBG8657260.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(14681..16117)
                     /locus_tag="KRH82_004025"
     CDS             complement(14681..16117)
                     /locus_tag="KRH82_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBG8657261.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKGSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIVFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
BASE COUNT         6214 a         1772 c         2715 g         5571 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattacat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggt catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtt gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatattaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattattt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatggt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattttttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgtgt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt atgaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt acctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtattgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tattggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acaatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggac
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc ttcctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaaa ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggc
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtgtaa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcaaa tgaattattg agcagagtag gaaggaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttaatctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agctataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ttacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttcc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggtgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttattg
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactctatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaacgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgcaggc tttagtgtca aaggatatag tgaattagaa
    13621 gtagcaaaga aaacagctga taagttaggt atagaaaata tccagattaa tataacacaa
    13681 gatgaatata taaaatcatt accgaatgta atttattctt tggatgaccc tatagcagac
    13741 ccttcagaag taggtcttta tttcttaatt aaagaggcag gtaaacatgt taaagtagca
    13801 ttgtctggag aaggagcaga tgaattattt ggaggatata atatatataa agagtatagt
    13861 actatgaaat cagttgtcaa ttcacctact tatattaaaa gtatattagg aagagtttca
    13921 gaacttatgc caaacataaa aggaagaaat tatctttata gagctacaac accattagaa
    13981 aaaagatata taggaaatgc aaaagttttt gaaaacagcg aagtaaaaag attctttttt
    14041 aagtataagg aaaagaatat atatgaatac ctgttgtcta atttgtatag agatgcacaa
    14101 aaaaataatt acgattatat aagtaaaatg caacatatag atgtgaatac atggcttcaa
    14161 ggcgatatac ttcaaaaaat tagcaaactt tctacagctg agcaggttga acttagagta
    14221 ccatttttat ataaagatgt atttgatgta gcaaaaaatt taagaatgga gcaaaaaata
    14281 aataagaata atacaaaagt tttacttaga gaggcgttta gagaaatagt cccagaacat
    14341 gttgttcaaa ggaaaaaatt aggatttcca actccaataa gagtttggtt aaaagattct
    14401 ctaggggata ttgtaaagga aactatttat aattcaaatg tagatgaatt tatagataaa
    14461 aaatatgcaa taaaactttt agatacgcat cttaaaggtc atagagataa ttcgagaaaa
    14521 atatggacta tatttacatt ttgtctatgg catcaattat ttattgagca taaaaatgtc
    14581 gagtattaat acttttttca atattaatca gagggcaaaa gcatgcaatg ttttcaccct
    14641 cctgattatt atggaatagg ataagtagaa ctttgattga ttagtttact atctcaataa
    14701 aattattggc aaatattttg acaagattac tttcaacagc taaatttaag ttttgtccat
    14761 catcatatcc agcggaaatc aatcctagta agtttccaaa catatctaaa agagctcctc
    14821 ctgaactacc actagagatt ggagctgtaa attgtatcat ttgaaccgtt tcaaaatcac
    14881 gaaaagctga aataattcca tctgaaactg tattaaaaag acctaaaggg cttccaattg
    14941 caactatttt ttgacctctc acaggttttt tactgacttt aacaggtatt ggcttgcatt
    15001 ttctattaac ctttatcaca gctaaatcat aatctgaatg gtattttata atttggtaag
    15061 atgtataaac tttatcatca ttttcaaatc taactaaaaa tgaataccca tcattgacta
    15121 catgaagatt cgtaagtata taaccttcat tatttattac tactccagaa ccgctcttaa
    15181 acggtttatt ttcgttattg cacacaacaa tcataacaac agaagctgat aactttgcaa
    15241 ggtcttcata agaaagttct acttcctcat cttgtacaat ttttttagat gttagatttg
    15301 tgttattaag tgtattttta gagttaggtt tattcgtagt aggagaagtc ttattggtat
    15361 tttcactgta atttatattt gtaatatgcc tttcaaaagg tatttctaat atatttggag
    15421 tcttcctaga aagttcaaat agagtagaaa attttgaaca ttcaggatat aaatcaagaa
    15481 tatctttatt tggatttata tataaaatat cacacccaag ttgtgataaa aaatataaga
    15541 aaaaaagttc ttgcctttta atatttccaa agtatactat ctttggtgaa atagtagtct
    15601 tcaccttgtt ataaaataat ttaggtagaa aatagtccat ccaacacaaa agtttaactg
    15661 caaagttttt gatgatagag gatgtacaat ttggcatact tgtggaaaat aaatctaaag
    15721 tatttttaaa tacaatcttt ttagtccaat ttaaggtgtc attttctatt ttacatggaa
    15781 agtcgatatt atataaatcc caactgttaa acttagaact atcataaata ttaaaaattt
    15841 taagcatctt atctgtttgt tctttgtcaa aatttatttt tagattgttt aatctaatat
    15901 agggaattgt aggattatta aaaaaataag tatctatatt tttaattttt tctatgtatt
    15961 tatcaattga atcatcaaca cctatatatc ttgtaaagta gacttcttta atatatgaag
    16021 aacccttatt tttataggta gtatcagata taaattcaat tagaggttca gtagactttt
    16081 ttattgaaat ctttaatggt ttaatagtac aaatcatatt ttttctccta taataagatg
    16141 atataatcta ttataaaaca acttaaaaca atatagtaca ataattttgt agtttcaaaa
    16201 taaaatatgt acttgtttat ataaatgata tataattaca tattaaacat agcttttata
    16261 catttaataa ag
//
LOCUS       DAEOTL010000254        11147 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.guided.112, whole genome shotgun sequence.
ACCESSION   DAEOTL010000254 DAEOTL010000000
VERSION     DAEOTL010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.guided.112"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            complement(214..2301)
                     /locus_tag="KRH82_004026"
     CDS             complement(214..2301)
                     /locus_tag="KRH82_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBG8657262.1"
                     /translation="MIKVVYMRKNKKTRKMIIFGFLMCLLIVIIVFLAKFILDGLNKN
                     KPDEVFKQYMSFANKKQYEKMYDLLDEKSKSENKKEDFVLRNKKIYEGIDAHDISIKI
                     NDIKKNKNNDKVINYDSKMDTLAGEISFSNEVLLTRDRQKNYKIKWQSNVIFPELEED
                     NTVRVSKLKGKRGRILDRNGVMIAGQGLASMIGLVPGKMSDNIEDLKKLSTLLNVSVE
                     QIEKKLNASWVKENSMVPIKTIEKIKENTDGTVKEEDKELQESLLSIPGVKISNTEVR
                     VYPFGEKTGHLTGYVQNVNADILKEKEGKRYNDNSIIGKIGLENLLEDRIRGIDGYEI
                     IIADRYGDKKETLVTEPKVDGEDVKLTIDSKLQSKLYDQMKNDKGCAVVMNPKTGEVL
                     SLVSSPSYNPNEFILGMSEDRWNELNKNENKPMYNRFKARLCPGSSFKPVTAGIGITT
                     GKINPNENFGHSSLSWQKDSSWGSYKVTTLKDYGNTANMKNALIYSDNIYFAKAALKI
                     GEDVLAKELLKLGFDESMPFEFGLSSSKFGTDNKFETEIQLADTGYGQGKLLVNPVHT
                     ASIYSAFVNDGDMIKPHLEFKKAEFWKKGVFSKEAVKIIRDDLLQVVESPDGTGHSAM
                     IKGISIAGKTGTAEIKASKDDVTGTELGWFNAFTVDENSDKQYIVIAMIEDVKSRGGS
                     HYVIPIVKSVFED"
     gene            2662..3240
                     /locus_tag="KRH82_004027"
     CDS             2662..3240
                     /locus_tag="KRH82_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBG8657263.1"
                     /translation="MPTKGEQTKQFIIDTSIMLFSEKGYSNVTMKDICEACNLSRGGL
                     YRHFNSPKEIFISILNTHKYYSQNLLDKGIKENISAKHMLEYFFQQQKADINGKYCGF
                     DFAIHEFAFVEKDQRDYMNKRYSSAITMLSNLIDYGQSKSEFKKCDSKSVAIHIMFLF
                     DSMKTSASILKLTNKDIDNQINIIKDMVILYE"
     gene            3233..3892
                     /locus_tag="KRH82_004028"
     CDS             3233..3892
                     /locus_tag="KRH82_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBG8657264.1"
                     /translation="MNKQKFHKINLQNWERYTHFYYFSKMTNVGFNLTIEIDITNLLK
                     ETKKRNIKFYPAYLYTITTCLNRYRELKIAYDEDELGYWNTLTPLYAIFHDDNKTFSS
                     IWTEYDENFSIFYENYLADVKEYGKNHGFLAKPNPPRNCYTVSCLPWISFKSFTVHNH
                     GLENYFFPTIEAGKYYQKDEKILLPLSITVHHATTDGYHVSCFIDYIQKMCFNTKIWL
                     H"
     gene            complement(4103..5977)
                     /locus_tag="KRH82_004029"
     CDS             complement(4103..5977)
                     /locus_tag="KRH82_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBG8657265.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMIKDRETINDKK
                     VEKVNEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(5982..7646)
                     /locus_tag="KRH82_004030"
     CDS             complement(5982..7646)
                     /locus_tag="KRH82_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBG8657266.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESEDVIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVCLKPFHAVLLKAR"
     gene            complement(7660..8481)
                     /locus_tag="KRH82_004031"
     CDS             complement(7660..8481)
                     /locus_tag="KRH82_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBG8657267.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(8580..9344)
                     /locus_tag="KRH82_004032"
     CDS             complement(8580..9344)
                     /locus_tag="KRH82_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8657268.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(9341..10090)
                     /locus_tag="KRH82_004033"
     CDS             complement(9341..10090)
                     /locus_tag="KRH82_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBG8657269.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(10594..>11147)
                     /locus_tag="KRH82_004034"
     CDS             complement(10594..>11147)
                     /locus_tag="KRH82_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBG8657270.1"
                     /translation="FIVFDKEIILIDTGLPFMGKNIIKELKTLGIKLTDIKHILLTHH
                     DVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKKFIGKAISRRLIKDVEPYG
                     ENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNGNIVPYPNPWNWDYKKMMK
                     SIRELDNLKYEWICMSHGTPCIK"
BASE COUNT         3795 a         1958 c         1188 g         4206 t
ORIGIN      
        1 tggcaactct ccctcacatc ctcaattgtt gccactattt aattttttgt atgaagttaa
       61 atatattttc atcatttcaa caataaaaaa gaggtctatc tctattttga aacaacctct
      121 ttaattattt tagagtttac taagaagtct aaaaacaatt tatctaaaat attattctca
      181 actgagtaag attaatttcc aaattgagta aatttaatct tcaaacactg atttaacaat
      241 aggaataaca taatgacttc ccccacgact ctttacatct tcaatcatag caattactat
      301 atattgttta tcactatttt catctacagt aaaagcatta aaccatccaa gttctgtccc
      361 tgtaacatca tcttttgatg ctttaatttc tgctgtacca gttttcccag caatgctaat
      421 tcctttaatc atagcactat gacctgtacc atcagggctt tcaacaactt gaagtaagtc
      481 atcacgaata atttttacag cctctttaga aaacacacct ttcttccaaa attcagcctt
      541 tttaaattca agatggggtt ttatcatgtc tccatcattt acaaaagctg aatatattga
      601 tgccgtatgt actggattta caagaagctt accttgtcca tagccagtat ctgctaattg
      661 tatttcagtc tcaaatttat tgtcagtgcc aaattttgaa gaagacaatc caaattcaaa
      721 tggcatactt tcatcaaatc caagcttcag caactctttt gctaatacat cttcacctat
      781 ttttaaggct gccttagcaa aataaatatt gtcagaataa atcaaagcat ttttcatatt
      841 tgcagtattt ccataatctt ttaacgtggt taccttataa cttccccaac tagaatcttt
      901 ttgccaactt agactgctgt gtccaaagtt ttcatttgga ttaatctttc ctgttgttat
      961 accaatacca gcagtaactg gtttaaaaga agacccagga cataatcgtg ctttaaatct
     1021 attgtacatt ggtttatttt catttttatt gagttcattc catctatctt ctgacattcc
     1081 caatataaac tcatttggat tgtacgacgg actacttaca agtgataaaa cctctcctgt
     1141 tttaggattc ataactactg cacaaccttt atcatttttc atttggtcat atagtttact
     1201 ctgtagtttt gaatctatag ttagctttac atcttctcca tctacctttg gctcagttac
     1261 taaagtttct ttcttgtcac catatctatc agctattata atctcatatc catcaatacc
     1321 acgtattcta tcttccagta aattttctaa accaatctta ccaattatac tattatcgtt
     1381 gtacctctta ccctcttttt cctttagtat atctgcattt acattttgaa cataaccagt
     1441 taaatgaccg gttttttcac caaatggata tactctaacc tctgtattag atattttaac
     1501 tccaggaata ctaagaagtg actcttgtag ttccttatct tcttctttta cagtaccatc
     1561 tgtattttct tttatttttt caatagtttt tataggtacc attgaatttt cttttaccca
     1621 agatgcattt aatttctttt caatttgttc aactgataca ttcaataaag tagataattt
     1681 ttttaagtct tctatattat cactcatttt tccaggaact aatcctatca tagatgcaag
     1741 accttgacca gcaatcatta caccgttcct atccaggata cgtcctctct tacctttcag
     1801 ctttgatacc cttacagtat tatcttcttc aagttctgga aatatgacgt ttgactgcca
     1861 ttttatttta taatttttct gtctatctct agttaatagt acttcatttg aaaatgaaat
     1921 ttcacctgct aaagtatcca tcttagaatc atagtttatt actttatcat tatttttatt
     1981 ttttttaata tcattaatct taatacttat atcgtgtgca tcaattcctt catagatttt
     2041 tttatttctt aaaacaaaat cttctttttt attttcagac ttgctctttt catctaataa
     2101 atcatacatt ttctcatatt gttttttatt tgcaaaagac atatactgct taaacacttc
     2161 atctggtttg tttttattga gtccatctag tatgaatttt gctaaaaaaa caataataac
     2221 tataagcaga cacattagaa aaccaaaaat tatcattttt cttgtttttt tattttttct
     2281 catataaacc acctttatca tttaatatat tacatacgta agctttaagg ttaaaatact
     2341 cttatagaca taactaatct atgtttttat tatgttttta agtatctcat aaaaatatgt
     2401 aagcagtata attgatagta acttatatat tacacatgta agttttaaaa gtcaataata
     2461 ttatcattat ttaattattt tttacatcaa cttaaaaata aatcagttcc attatattct
     2521 tttgtattct tcaactattt tataaattaa ccttattcta ttgtaattat tttatagtat
     2581 ataactttaa cttgacaaaa cgacacaagt gtctcataat taaaagtgac acttatgtcg
     2641 ttaaaaagga ggttaaaaca tatgccaaca aaaggagaac aaactaaaca atttatcatt
     2701 gatacatcaa taatgctatt ttctgaaaaa ggatatagta atgtgacaat gaaagatata
     2761 tgtgaagcat gtaatttaag ccgtggtggc ctatatagac actttaattc accaaaagaa
     2821 atttttatca gtatattaaa cactcataaa tactactctc aaaatttgtt ggataaaggt
     2881 atcaaggaaa atatatcagc taagcatatg ctagaatatt ttttccaaca acaaaaggct
     2941 gacataaatg gcaaatattg tggatttgat tttgcaatac acgaatttgc ttttgtagaa
     3001 aaagaccaac gtgattatat gaataaaaga tacagttcag ctatcacaat gctttcaaat
     3061 ttaatcgatt atggacaatc taaaagtgaa tttaaaaaat gtgattctaa atcagttgca
     3121 atacacataa tgttcttatt tgatagcatg aaaacatctg cttccatttt gaaacttaca
     3181 aataaagaca ttgataatca aataaatatt ataaaggaca tggtgatttt atatgaataa
     3241 acaaaaattc cataaaatta atttacaaaa ctgggaacga tatacacatt tttactactt
     3301 ttcaaaaatg acaaatgtag ggtttaattt gactatagaa atagatatta ctaatttgct
     3361 taaggaaacg aaaaaaagaa atattaaatt ttatccagcg tatttatata caataactac
     3421 ttgcttaaat cgatatagag aactaaaaat cgcatatgat gaagatgaac tcggatattg
     3481 gaacacgtta acgccacttt atgcgatttt tcatgatgat aataagactt tctcatcaat
     3541 atggacagaa tatgatgaaa atttctcaat attctatgaa aattatttag ctgatgttaa
     3601 agaatatgga aaaaatcatg gttttctagc aaaaccaaat ccgccaagaa actgctatac
     3661 tgtttcctgc cttccatgga ttagctttaa gagttttact gtacataatc atggtcttga
     3721 aaattatttt ttccctacaa ttgaagcagg taaatactat caaaaagatg aaaaaatact
     3781 tcttcctctt tctataacag tgcatcacgc aactactgat ggataccatg taagttgttt
     3841 tattgattac atacaaaaaa tgtgctttaa tactaagata tggctacact aaaaatttat
     3901 acaatataaa aagaactgtc gcatgagcaa attaaatttg ctatgagaaa gctctttttt
     3961 acttacaata gttaatatga gatgaattat ttcttatact ttgaacttac caatagttaa
     4021 tatgaaatga attatttctc atactttaaa aagattgaat tactcttgat aatcttcttt
     4081 tgtagtcatt acatatcacc tactactcaa cacatattct ttgacctatt tttacatcct
     4141 tgtttatatc caaaatattt accttcttac catctggaaa caataccatt gttaaagtag
     4201 actttcctaa ttcgtgtatt ctctttaaat caacattaac aagaacgtct ccctgtttaa
     4261 ccatatctcc ttgtttaaca gcaacatcaa agccatctcc atttaatgca actgtatcaa
     4321 ttccaacatg aattaatact tctccattag ttcctttaat cccaaatgca tgtccacttg
     4381 aaaatactgt ttctaattta cctgaaatag gagaaacaat ttttccatct ataatatcaa
     4441 tagcaaaacc atcacctaac atttttttag aaaatgtttc atctggtaca ttttctaatg
     4501 caacaatttt ccccttagct ggagacacaa agttttcatt attttcatta aacactaatt
     4561 cttcgtcttc atcttcattt atagcttctt taggcactcc aaataaacat gttacaataa
     4621 agcagaatgc aaccacaaat attgatacta ataagtatgt gattaaatta tatccatcat
     4681 agatatacat taaataagaa ggtaaaactg ctaatccata tgaattagat tgaatatgta
     4741 aaattgataa tattgctgct cctaaacctg aagatgcaca cataataatc aaaggcttta
     4801 aattatatcg aagctgaatc ccaaataaaa caggctcact tataccaaaa agttgagata
     4861 gcattgctcc aactgcagtt tgtttaactt gattattttt agattttttc ataaatgcta
     4921 gacatgttcc aatattcgca aatccataca ttgcacaaag agtaataagg gcattaaatc
     4981 ctgtatttgc taatagtgat gtttcaatca ttacataagt atgatgtaag ccagtaataa
     5041 cagctaatgg atatgtaaat ccaataataa atcctccaat tcctaaaggc aaatcaatca
     5101 ataagctgat gatatcaacc atttttaatt ctattgtatg cattataggg cctacaccta
     5161 ataaaataac taacattgtt attagcataa caaagaatgg tgtgaaaata aggtctaata
     5221 cattaggcat atgtttacgg aaccattttt caagattagc tccaataaat gctgtaacaa
     5281 tagctgttaa aacacttcct tgacaaccta caataggaat aaatccaaat gccataattg
     5341 cttcaatttc atttgatggg tcagcaacag aatatgcatt aggaagtatt ggggaaacta
     5401 acataagtcc aataacaagt ccaataacag gtgttcctcc aaatacttta aatgctgacc
     5461 atacaataat tgctggtaaa aaagcaaatg ctgtttctgt aagaaccgaa acaagtgtct
     5521 gaatatacaa tggaatattt gcagaagaca ttccaaataa tccaagtaca ttatcattaa
     5581 acaaacaacc ctttaatccc aagaataatc ctgttgctgc aataactgga ataataggaa
     5641 caaatatatc tgctagagtt ctcataactt tcttaaatcc agtttcatta tttttaacta
     5701 attcatcttg ttcttttttt gataaagttt ttaatcccat tttttcaact tctgcataaa
     5761 ctttattaac tattcctgtt cctaaaataa tttgatactg tccagaagta aagaaaacac
     5821 ctttaacctc attgaccttt tccactttct tatcattaat agtttcccta tctttaatca
     5881 tcacccttag tcttgttgca caatgtgtaa tagaaataat attatcttca ccaataattt
     5941 taataagctc atttgctatt ttattatatt tattcatttt tctacctcgc tttcaataat
     6001 actgcatgaa atggtttcaa acacactgtt ttatttaata gatttatatc atctaaattt
     6061 tggaatacaa tatcatattt ttcttctact cttatttcta caggtttatc agaaaaatta
     6121 taataacaat caataactac caaatctaat tgccttctat acgcaataac atcttcactt
     6181 tctatatcaa taggttctat tgaaccataa atcaaacaat cagaatactc actatcttgt
     6241 ctcaacttta tcatcttttt ataaaattct aaaatactct ctgaattgtt aatctgactc
     6301 tgtgcattaa tatctttata attttcaata acctttaacc atggtgttgt atctgaaaaa
     6361 cctgcatttt ctttatctgc ccatggaaat ggcgttcttg cattatctcg gcttcttaaa
     6421 ttcacaaatt ctaacgcttc ttcttctgag taaccttcat ctattgaacg atagtattgg
     6481 tcaatgctag ataaatcatt aaaatcattt atggtatctc ttttaaaatt tgtcattcct
     6541 aattcctgcc cctgataaat aaatggggtt cctcttaaaa agaaatacat tgctcccaac
     6601 atttttactg catcatcatt cctttcgtat tgcaaaagat actttgttgt agctcttggt
     6661 tggtcatgat tttcaataaa attagctgcc catccatgtt cctgaacata catttgacta
     6721 tctaaaatgc attttcttaa atctggaatt gtccatgaaa ttcttttaaa ccactcacta
     6781 ccagaagcaa catctaagtc agcatgttta aagtcaaaga ccattgaaaa gaaaccatct
     6841 tctccaataa aatcacctaa ctggtcatag ctaatacctg ctgcttcagc aacagtcata
     6901 caatcatatt ttttaaacgt attttctttt aattcataaa gcattttttc tattccaggc
     6961 tgatttctaa ctgtttttgt acatttaaca agaccatcaa caccatcact ttctaaactt
     7021 tgaaaactta aattcttttt gatgaatgta atagcatcaa ctctaaatcc tgccactccc
     7081 atttgagacc aggtattaat catttggtaa agttcacttc ttaatattgg attttcccaa
     7141 ttaaggtcag gttgtttttt accaaaagaa tgaaaataat attcgtctct attctctacc
     7201 ttttcccaaa cacttccacc aaaaacagac ctccagttat ttggtaaatc gtttcctttt
     7261 ttaaaaatat aataatcatg ataaggactt tctggatttt ttaatgcttc ttgaaaccaa
     7321 ggatgttcat cacttgtatg gttaagaact aaatctaata taattttgat tcctctatct
     7381 ttactttctt taattaactc ttttaaatct tccatacttc caaattcact tgcaatatcc
     7441 aaataatcac taatatcata cccattatcg tccataggtg atttaaaaat tggacataac
     7501 cacaatgatg taatacctaa atcttttaaa taatctaaac gagaaataat tccctgtaaa
     7561 tctccaattc catcattatt actatcttga aagcttcttg gataaatttg ataaacgatt
     7621 tctttttgcc accatttctt ttccataaat tactcctttt tatatgatat ttcttctttt
     7681 taattcttta taaattccat tatcgaatat gtcctcacat atagatgtcg ctatatcttt
     7741 aagttgttga tgactatttt tcattgcaat tgtaacgtct gatgcttgaa acatgacaat
     7801 gtcattttga ccatcaccaa aacatatggt ttctttttga gttactccta atctttcttg
     7861 taatctctta attgctttgc ccttatgaaa atctttttga ataatttcat aatactgact
     7921 agaaatatct ctctgtgcta attccatttt atcttgtagt atatctttca cttcgtcaaa
     7981 taccttttca tttgaccata aacaaatttt atgtatatct tgtgacttat actcttcaat
     8041 gttattttca tatgttattt tttcttggat atgttgttta tttatacaag aattagttcc
     8101 tttcaactga ttcattgttt caaatatttc tttggctttt tgattcatga aaactttttc
     8161 ctgactctca atcgaaaaag caacttccct cttttttaat aaacaaacaa cttcctttat
     8221 caatctttga ttaaaagatt gattataaag taattcacca tgatattgaa tgtaattacc
     8281 tcctcctgca atatatccat caactcctaa tgataaaaca tcatcttgta ttgtacccat
     8341 acttcttcca gtacaaataa caacactaca atgattcttt tgacataaac gtatagcatg
     8401 ctttgcagat tctgggattc catatacctc atctctaagc gtaccatcta tatcaagtat
     8461 taataatttg tacaatttca tcttcctttc ttactatcaa aatcataata gcattcaaaa
     8521 aaaaagatat caatattttg atatctttta aaaaatatgt tcatttttag cacaaatttt
     8581 cattttcggg gaatatgttc actttctaaa tacatcttgt atttaatata aagcagttca
     8641 attaaaataa aataaggtgt tgttacatcg tagtccagtt gtttatctac agaaatagat
     8701 atagattgaa tatacaggtt ttcatcacat aatcttgcta aaggattact tatcattttt
     8761 gtaatagaaa ccatataaat tcctttcatt ctcatttctt tagcaaaatc aataattgta
     8821 gatgcatctc cattcaatga aataaagaaa atcatatcat ctgtttttat aaaatgatta
     8881 agtgcctgaa tcatatcata accataaaca tcatatataa ttttccctgt tggtaagaaa
     8941 atccttttca tctctttagc aactctttcc tgagaataac cttctccaaa gacgattata
     9001 cgatttgcct ttttcattct ttcaaacata atcgaacaat ccttcttctc tatatcatct
     9061 atcaccttat tataacaatc cattaattgg tgtttacttt gatttttata ttctacttct
     9121 gtttcattta agcgtataat aactcttaat tcactatatc caggtaattg tagtttttga
     9181 gcaaaacgag aaagtgcact tgtagatata tggtatttgt ctgcaaattc atctatagaa
     9241 agtttaatac aatcttcttt atgattaaga atacactcac agatatactt atcatttgct
     9301 gtaaatgaat tataatattt attgaaaagt ccttcaattt tcattctttt ctccttctat
     9361 actctatgta attcatatga agcaaatcta atagagcata aaatgctcct acgacttcat
     9421 aagatatagc ttgtaatgta tcaagttttt gagtttcaac atacagatta tactcacaaa
     9481 gtgttgcaat tgtattatta tcaagcctag ttaaagaaat cgtatgtata tgattgttga
     9541 taaattttgc aatttcaatt cctgcttttg tttctccaga taaagaaata ataataaata
     9601 aatcactttt ttgaaatgat tctctcataa attcaatttc acctatatca aataagtcaa
     9661 taacacattt acctactgaa agaaatattc tctttatttc ttgagctaaa cttttctgtt
     9721 cattacctgt cccataaata taaattgttt ctgcatcata tattatttta caaatatctt
     9781 gaaatgatat tttttgtaat tcattcatta atagtcgata attctcgcaa acatcatgaa
     9841 aattattatc attattaaca aattctagtt gattattttt aagtaaatac tttaaatcag
     9901 agaatgaatc taatccaatt tttctacaaa gccttaataa agtagctcta gaaacattac
     9961 attcatttgc aattttttca cacgaaaaat tacggtattc tctttgacaa atcaatattt
    10021 gtttaataat aattttatca ttttcattta aattatcata attttggtta actaacgatt
    10081 ctaatctcat tttttccact ccctaaatat tattttaata tacattagtt gctttttcta
    10141 gggaagagtt ttaaataata aggataaaat aatcatttga ttttattttt attaaaataa
    10201 aaataacctg ctaaaagcag gcaccaaaaa gtacttatcc tttcgaacat gtactttaga
    10261 tattgctttc ttcggaagct tcatctcttc atactctaaa atagagtttt ttctaactca
    10321 aaagtatttt ccatggtaga aattacttta attcatctgc catttatttt ttatcttatt
    10381 taataattac tactacttga atatttactt ctttaagtaa atttcatagt taacaaagct
    10441 aaaactatta ttatagatgt taaaatacaa aattgtaagt attgttataa atatgcttac
    10501 agctacaaat atacatgata tattaaaaag aagctgtaaa ttattatcat acatacaagc
    10561 aactacgcct ctattaatcc atgttaattt ttattattta atacaaggag ttccatgaga
    10621 catacatatc cattcatatt ttaaattatc caattctctt atagatttca tcatcttttt
    10681 ataatcccaa ttccatggat taggataagg aactatattt ccattcttat ttttgactaa
    10741 atcacctgca aataatacat cttcaaaaat catgcagaca tgccctggag tatgaccagg
    10801 agtatggata atttttatat tcccaatctg catattctct ccataaggtt caacatcctt
    10861 aatgagcctt ctggaaattg cctttccaat aaacttctta aacccaggtc tatccttctc
    10921 tcctataata aaaggtatat cctctacatg agcccatact tttgctcctg ttttttcttt
    10981 caataattta atattagata tatggtcaac atcatgatga gttaataaaa tatgcttaat
    11041 atctgtaagt ttaataccaa gtgtttttaa ttctttaatt atatttttcc ccataaaagg
    11101 aagacctgtg tctataagaa taatttcttt atcaaacaca ataaaac
//
LOCUS       DAEOTL010000255         4057 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.guided.173, whole genome shotgun sequence.
ACCESSION   DAEOTL010000255 DAEOTL010000000
VERSION     DAEOTL010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4057
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.guided.173"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            <1..866
                     /locus_tag="KRH82_004035"
     CDS             <1..866
                     /locus_tag="KRH82_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657271.1"
                     /translation="SALSKSDLNSLLLEVFDRQANTLTATDILKSYQLNRFTIPSGID
                     PEEIHALESNLLRKAFNMDIKTIMLSPSAPLGSCSVFGSVDQYNVVSALRGTETLADP
                     SNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNFVGKGLYSHFGLYCMVSSGIDT
                     GSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRNGYKDNDGFFDRMVETIKLIFP
                     NIELSIHNDDVDNNYYKGINFKISVKQGNETVEIADGGFVDWTYQMLGNKKERCLISG
                     IGLERFLVAVS"
     gene            880..1329
                     /locus_tag="KRH82_004036"
     CDS             880..1329
                     /locus_tag="KRH82_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBG8657272.1"
                     /translation="MELIEWNYAYITELVEFANDKEIANNLRDNFPHPYREQNARDFI
                     SFCLATPDVKQLSYAIFYQERAIGSISLTFEEDTSINKNAELGYWLARNYWGKGIATN
                     AIKEICKIAFEKYNLNKIHANVYSYNRGSSKVLEKCGFKIEEYCHNS"
     gene            1689..2096
                     /locus_tag="KRH82_004037"
     CDS             1689..2096
                     /locus_tag="KRH82_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBG8657273.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            2098..2328
                     /locus_tag="KRH82_004038"
     CDS             2098..2328
                     /locus_tag="KRH82_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBG8657274.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(2380..2589)
                     /locus_tag="KRH82_004039"
     CDS             complement(2380..2589)
                     /locus_tag="KRH82_004039"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBG8657275.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLPIKNHNSLWAFIDK"
     gene            2718..2921
                     /locus_tag="KRH82_004040"
     CDS             2718..2921
                     /locus_tag="KRH82_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBG8657276.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            2999..3352
                     /locus_tag="KRH82_004041"
     CDS             2999..3352
                     /locus_tag="KRH82_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBG8657277.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            3424..4056
                     /locus_tag="KRH82_004042"
     CDS             3424..4056
                     /locus_tag="KRH82_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBG8657278.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         1516 a          589 c          700 g         1252 t
ORIGIN      
        1 tatcagctct atcaaaatca gatttgaact cacttctatt agaagtgttt gatagacaag
       61 caaatacttt aactgcaact gatattctaa agtcatacca actaaataga tttactatcc
      121 ctagcggtat agatccagaa gaaattcatg ctttggaatc aaatttattg agaaaagcat
      181 tcaatatgga tatcaagacg attatgcttt ctccctctgc cccattaggt agctgtagcg
      241 tttttggctc cgtagatcaa tataacgtag taagtgctct acgagggaca gaaacacttg
      301 cagacccctc aaatatgttg gcaataatta ttgctgataa attaaaaaga aaagaagaaa
      361 ataataccat acctatccac atggctacta ctgctagggt aataagagca caaaattttg
      421 taggtaaagg tttatattca cattttggct tatattgtat ggtttcatct ggtatagata
      481 cagggtctta cacttgtgaa aaaatgttgt tagaaaagca cttaaactat tataaagata
      541 tattaagtga aatagaaaat gttcgtttct ctattattct acgcaaaaga aacggataca
      601 aagataatga cggatttttc gacagaatgg ttgaaactat caaacttatt tttcctaata
      661 tagagttatc aattcataat gatgatgttg ataataatta ttataaaggt atcaatttca
      721 aaatatcggt caaacaagga aatgaaaccg ttgaaatagc tgacggtgga tttgttgact
      781 ggacttatca aatgcttgga aataaaaaag aacgctgttt gataagtggt attggcttag
      841 aaagatttct tgtagctgtt tcataaaagg agaagaaaaa tggaacttat agagtggaat
      901 tatgcttata ttaccgagtt agttgagttt gcgaatgata aagaaattgc aaacaatctt
      961 cgtgacaact tcccccaccc ttatagggag caaaacgcta gagattttat tagtttttgt
     1021 ttggcaactc cagatgttaa acaacttagc tatgctattt tttatcaaga aagggctatt
     1081 ggaagtatca gcctaacatt tgaagaagat acctctatta ataaaaatgc tgaattaggt
     1141 tactggcttg ctaggaacta ttggggcaaa gggatagcaa caaatgcaat aaaagaaata
     1201 tgcaaaattg cctttgaaaa atacaacctt aacaaaattc atgctaatgt atattcctac
     1261 aatagagggt caagtaaagt attggaaaaa tgtggtttta agattgaaga atactgtcac
     1321 aattcataat aaagaataga aacatgattg attgccatgt atatagttta attcgaccgc
     1381 aatagcattt attagaatta acctactttt taataacaga ataagttttt cccctctatt
     1441 aatttcttat gcatctttgt atttttatga aaagctagcc aatgcatatt tccatacatc
     1501 aatatggtgg tggcttacaa ccaatataaa ttaaatacgt tttaaagaat acacattttt
     1561 gccctatagg cagagtgtgt atttttttct cttttttttg aaatttatcg aagatttaat
     1621 tccctcccac cgtgatagga gtaagcaagg ttatttaact ccttgcgatg gaaagagggt
     1681 gaaatcttat ggttgatgaa aagacaattg aacatcaatt cgacagtttc tgtaaaacag
     1741 ttttgcgtaa ctatgctaga gatatttatg acgaaaataa acgcagaaat gattatttgg
     1801 tatctctcga atctttgtca cttgcagaat taagtaaatt gagtatttta gatgattatg
     1861 attctaacta catctgtatg gtttcttacg actacaacat acgaattgaa gatgtattaa
     1921 tggcacaagc aatcggaaaa cttacaaaaa gaaaacaaga tataattcta ctttcattct
     1981 ttctcaacat gacaaatgct gacatagcaa cattgatgga tttagcagaa aataccatac
     2041 attatcacaa aacaaatgca ctaaaagagt tgaaagaact catggaggaa cattgaaatg
     2101 aaacctacta aagaagtatt accttttaca attattttac ttgctgtaca tggcgatgta
     2161 aatgcaataa acggaatact taaacatttt gaacactata tcattcgtct ttcacagaaa
     2221 actttatttg atgaatacgg aaatccctat attcatgtag aagaagaaac aaagcgaatg
     2281 ctaggaacaa aactaatcac tgctattttg agatttaatt tgtcttaatc tcgccctctc
     2341 tccatgtatc aagctatttg gtacatggag aatcactaat tatttgtcta taaaagccca
     2401 caagctattg tgatttttta taggcaaatc aatgccgact gttctttgac aactgaataa
     2461 agtagataga tacgtttgtg atacagatag ccaacaaata ctatacgcca tgaccttaat
     2521 caagagagct actatatagt gatttgtgaa taacctttgg aacggttgtt ttgccgtaac
     2581 ctgtaccaca gtataatgat acacctgtat gacacggttc tgcccataag aatgggattg
     2641 gttgaaatac caatggagct taccaaagcc atctatctac ttctgaacta cgaacataga
     2701 aaggagtgat acattctatg aacaatactg atgtacctat ttgggaaaaa tataccttga
     2761 cgattgaaga agcgtcaaaa tactttcgta ttggagagaa aaaattacgt aaacttgctg
     2821 atgaaaacct tgattctggc tgggtcatta tgaatagcaa tcgcattcaa ataaagagaa
     2881 aacaatttga gaaaatcgtt gatacacttg acgttatcta atgaaattga gccttatatg
     2941 ttataatatt catatgacgt atcaagctca attcggttat tgagaggagc ttcttatcat
     3001 gtcaactgaa aaaagacgag ataataaaga tagaatttta agaactggag agagccagag
     3061 aaaagatgga agatacgcat ataagtatgt atattcattt ggtaaaccac aatttgttta
     3121 ctcttggaaa cttgtaccta ctgataaacc cccaaaggga aaacgtgatg atatatcatt
     3181 aagggataag gaaaaagcaa tacaaaatga ccttgatgat agcattgaca ctattggtaa
     3241 gaaaatgaca gtttgtcagt tatacgctaa aaagaatgta ctaagaaaga atatccgact
     3301 taacactaaa aaaggacgcc attatcttat gaagattctt aacaaggagt gattctgtga
     3361 agagatgtat tgtagtagtg gaatagtcaa aaacataata tatattaaag gagagattta
     3421 aatatgacta ttccaagttc aaataaggta tatccaagaa gtaatgatta tcaaactgta
     3481 tatcttaaaa atgtaataac aagggaaaat atagaagttg gagattacac aatatataat
     3541 gacttttata atgacccaag agattttgag aaaaacaatg tattgtatca ttaccctata
     3601 aacaatgata aattaataat tggtaagttt tgctcaatag catgtaatgc aaaatttcta
     3661 atgactagtg gaaatcactc aatgaaatca aaatccacat atacttttcc catcttttat
     3721 gaagaatgga aactcgatat caaccatata acggacgctt gggacaataa gggtaacatt
     3781 ataattggaa atgatgtgtg gataggttat gattctataa ttatgtcagg tgtaaatatt
     3841 ggtgatggtg caattattgg aacaagagca gtagttacta atgacgtccc accgtattct
     3901 attgttggag gagtacctgc aaaaattata aaaaagagat ttaataatga tacaatttca
     3961 aaattattag aaattaaatg gtgggattgg ccatataaaa aaattcaatc aaacattaag
     4021 catattcaat caggaaatat tgataaatta gtttaat
//
LOCUS       DAEOTL010000256         3417 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.guided.180, whole genome shotgun sequence.
ACCESSION   DAEOTL010000256 DAEOTL010000000
VERSION     DAEOTL010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.guided.180"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KRH82_004043"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KRH82_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBG8657279.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKCVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KRH82_004044"
     CDS             1575..2258
                     /locus_tag="KRH82_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBG8657280.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTYGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..>3417
                     /locus_tag="KRH82_004045"
     CDS             2255..>3417
                     /locus_tag="KRH82_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBG8657281.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLP"
BASE COUNT         1327 a          372 c          587 g         1131 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacttaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaataa taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtactacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaagga gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atgtaaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaatgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gctacatctg cttgggggag
     1741 tagatagacc tacatatgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac tcttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatttatag accagctatt ttattagcag atgagccaac tggtaatctc gatagaaaaa
     2101 attcagaaga aattgtagat ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg gattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggagatag aatcctaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gagactacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttggggtgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg atttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgcc
//
LOCUS       DAEOTL010000257         2522 bp    DNA     linear   BCT 16-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate CD-15-01019
            SAMEA5849372-rid12486623.guided.193, whole genome shotgun sequence.
ACCESSION   DAEOTL010000257 DAEOTL010000000
VERSION     DAEOTL010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA5849372
            Sequence Read Archive: ERR3473818
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (15-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 15-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001070366.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001070366.1
            Genome Coverage       :: 29x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/16/2021 00:25:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,051
            CDSs (total)                      :: 4,034
            Genes (coding)                    :: 3,974
            CDSs (with protein)               :: 3,974
            Genes (RNA)                       :: 17
            rRNAs                             :: 1, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 7
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 60
            CDSs (without protein)            :: 60
            Pseudo Genes (ambiguous residues) :: 0 of 60
            Pseudo Genes (frameshifted)       :: 25 of 60
            Pseudo Genes (incomplete)         :: 28 of 60
            Pseudo Genes (internal stop)      :: 19 of 60
            Pseudo Genes (multiple problems)  :: 9 of 60
            CRISPR Arrays                     :: 9
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2522
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA5849372-rid12486623.guided.193"
                     /isolate="CD-15-01019"
                     /isolation_source="stool sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /geo_loc_name="Germany"
     gene            83..298
                     /locus_tag="KRH82_004046"
     CDS             83..298
                     /locus_tag="KRH82_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HBG8657282.1"
                     /translation="MVVGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMDKALEEYIRKYLPDKL"
     gene            315..587
                     /locus_tag="KRH82_004047"
     CDS             315..587
                     /locus_tag="KRH82_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBG8657283.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            589..738
                     /locus_tag="KRH82_004048"
                     /pseudo
     CDS             589..738
                     /locus_tag="KRH82_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405294.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            799..1140
                     /locus_tag="KRH82_004049"
                     /pseudo
     CDS             799..1140
                     /locus_tag="KRH82_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002578721.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            1265..2002
                     /gene="erm(B)"
                     /locus_tag="KRH82_004050"
     CDS             1265..2002
                     /gene="erm(B)"
                     /locus_tag="KRH82_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBG8657284.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            2148..2432
                     /locus_tag="KRH82_004051"
     CDS             2148..2432
                     /locus_tag="KRH82_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBG8657285.1"
                     /translation="MPTKRSGPLVGKCPKCGNNIVLKKSFYGCSNYPECTFTLAEHFR
                     KKKLTKTNVKELLEGKETLVKGIKTKDRKSYNAVVKIGEKGYIDFISFSK"
BASE COUNT          956 a          379 c          482 g          705 t
ORIGIN      
        1 tcacaagtga ttaatcacaa atcacttgtg atttgtgatt gttgatgata aaataagagt
       61 aagaagaaat agaaagaagt gagtggttgt gggaaattta ggcgcacaaa aagcaaaacg
      121 aaatgataca ccaatcagtg caaaaaaaga tattatgggg gataagacgg ttcgtgttcg
      181 tgctgacttg caccatatta taaaaatcga aacagcaaag aatggcggaa acgtaaaaga
      241 agttatggat aaagccttag aagaatatat tcggaaatat ttacctgaca aactttaaaa
      301 ggagtgaaaa tgaaatggca gttacttatg aaaaaacatt tgaaatagag atcattaacg
      361 aattatcggc aagcgtttat aatcgagtat taaactatgt tttgaatcat gaattaaata
      421 aaaatgactc tcaattattg gaagtcaatt tattaaacca attaaagctt gcaaaacgtg
      481 taaatctttt tgattattct ttagaagaat tacaagccgt tcatgagtat tggcggtcaa
      541 tgaatcgcta ttcaaaacaa gttttgaata aagagaaagt ggcttaatat ggcaaatata
      601 gtcaatttta ctgacaaaca atttgaaaat cgcttaaatg ataatttaga agaattggtt
      661 caaggaaaaa aagcggttga atcgccaacc gcttttttac ttggtgggca accagggtca
      721 gggaaaacga gtttgcgaag aagatgattg agcaggcagg aacaaagtga taaattcaaa
      781 ttgtgaggga aaatatagat gaatcaagga agaattattg tgattacagg ctcaccgggg
      841 acaggaaaaa caacaactgc gtcaattgtc gcaaaggaat cagatatgga taaatcagtg
      901 catatgcaca ccgatgactt ttttcattac ttaagcaaag gcgcaatacc accacatttg
      961 ccagaatcca acaagcaaaa tctggttgtc attgaagcct ttttagaggc tgcaaagcga
     1021 tatgctcgtg gcggatatga tgtaattgta gatgggattg tcgggccatg gtttttggag
     1081 ccatggaaag ctcttgccca agaagattac gaggtacact atattgtatt aagagcgagt
     1141 atggaaataa gacttagaag caaacttaag agtgtgttga tagtgcagta tcttaaaatt
     1201 ttgtataata ggaattgaag ttaaattaga tgctaaaaat ttgtaattaa gaaggagtga
     1261 ttacatgaac aaaaatataa aatattctca aaacttttta acgagtgaaa aagtactcaa
     1321 ccaaataata aaacaattga atttaaaaga aaccgatacc gtttacgaaa ttggaacagg
     1381 taaagggcat ttaacgacga aactggctaa aataagtaaa caggtaacgt ctattgaatt
     1441 agacagtcat ctattcaact tatcgtcaga aaaattaaaa ctgaatactc gtgtcacttt
     1501 aattcaccaa gatattctac agtttcaatt ccctaacaaa cagaggtata aaattgttgg
     1561 gagtattcct taccatttaa gcacacaaat tattaaaaaa gtggtttttg aaagccatgc
     1621 gtctgacatc tatctgattg ttgaagaagg attctacaag cgtaccttgg atattcaccg
     1681 aacactaggg ttgctcttgc acactcaagt ctcgattcag caattgctta agctgccagc
     1741 ggaatgcttt catcctaaac caaaagtaaa cagtgtctta ataaaactta cccgccatac
     1801 cacagatgtt ccagataaat attggaagct atatacgtac tttgtttcaa aatgggtcaa
     1861 tcgagaatat cgtcaactgt ttactaaaaa tcagtttcat caagcaatga aacacgccaa
     1921 agtaaacaat ttaagtaccg ttacttatga gcaagtattg tctattttta atagttatct
     1981 attatttaac gggaggaaat aattctatga gtcgcttttg taaatttgga aagttacacg
     2041 ttactaaagg gaatgtagat aaattattag gtatactact gacagcttcc aaggagctaa
     2101 agaggtccct agcgcctacg gggaatttgt atcgataagg ggtacaaatt cccactaagc
     2161 gctcgggacc ccttgtagga aaatgtccta agtgtggcaa caatattgta ttaaaaaaat
     2221 cgttttatgg ttgttcaaat tatcctgaat gtaccttcac tttagctgaa cattttagaa
     2281 agaaaaaact caccaaaaca aatgtaaaag aattactaga gggaaaagaa accctggtaa
     2341 aaggaatcaa aacgaaagat agaaagtcct acaatgccgt tgtaaaaatc ggagaaaagg
     2401 gatatattga ttttatctct ttttcaaaat aagcataaaa gccctttaaa gagggctttt
     2461 atatattaat cacaaatcac ttatcacaaa tcacaagtga ttaatcacaa atcacttgtg
     2521 at
//
